Supplementary Table 19. All Sample.count.condition.,,,,,,,,,,,,,,,,,
GeneID,treat1,treat2,control1,treat3,treat4,control2,control3,control4,control5,control6,treat5,treat6,Symbol,Cellular_Component,Biological_Process,Molecular_Function,Pathway
1,71,0,0,0,0,0,50,86,29,107,4,0,A1BG;alpha-1-B glycoprotein,GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005615//extracellular space,-,-,K06512//Osteoclast differentiation;B cell receptor signaling pathway
100,0,0,0,0,0,0,0,0,34,0,0,0,ADA;adenosine deaminase,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0016020//membrane;GO:0030054//cell junction;GO:0032839//dendrite cytoplasm;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005764//lysosome;GO:0060205//cytoplasmic membrane-bounded vesicle lumen;GO:0005829//cytosol;GO:0005615//extracellular space,"GO:0002906//negative regulation of mature B cell apoptotic process;GO:0007155//cell adhesion;GO:0070256//negative regulation of mucus secretion;GO:0002314//germinal center B cell differentiation;GO:0006154//adenosine catabolic process;GO:0046111//xanthine biosynthetic process;GO:0042323//negative regulation of circadian sleep/wake cycle, non-REM sleep;GO:0050850//positive regulation of calcium-mediated signaling;GO:0001821//histamine secretion;GO:0007568//aging;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0060407//negative regulation of penile erection;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0001890//placenta development;GO:0042110//T cell activation;GO:0060169//negative regulation of adenosine receptor signaling pathway;GO:0042542//response to hydrogen peroxide;GO:0046103//inosine biosynthetic process;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0033197//response to vitamin E;GO:0001889//liver development;GO:0010460//positive regulation of heart rate;GO:0048541//Peyer's patch development;GO:0043103//hypoxanthine salvage;GO:0046061//dATP catabolic process;GO:0048566//embryonic digestive tract development;GO:0050728//negative regulation of inflammatory response;GO:0006144//purine nucleobase metabolic process;GO:0001666//response to hypoxia;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0002686//negative regulation of leukocyte migration;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0001829//trophectodermal cell differentiation;GO:0006157//deoxyadenosine catabolic process;GO:0043278//response to morphine;GO:0002636//positive regulation of germinal center formation;GO:0048286//lung alveolus development;GO:0044281//small molecule metabolic process;GO:0030890//positive regulation of B cell proliferation;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0043101//purine-containing compound salvage;GO:0045987//positive regulation of smooth muscle contraction;GO:0032261//purine nucleotide salvage;GO:0042493//response to drug",GO:0005515//protein binding;GO:0004000//adenosine deaminase activity;GO:0008270//zinc ion binding;GO:0001883//purine nucleoside binding,K01488//Metabolic pathways;Primary immunodeficiency;Purine metabolism
1000,0,0,0,0,0,0,0,0,35,0,12,0,"CDH2;cadherin 2, type 1, N-cadherin (neuronal)",GO:0005911//cell-cell junction;GO:0016324//apical plasma membrane;GO:0030027//lamellipodium;GO:0005913//cell-cell adherens junction;GO:0014704//intercalated disc;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005916//fascia adherens;GO:0016342//catenin complex;GO:0005925//focal adhesion,GO:0042692//muscle cell differentiation;GO:0010001//glial cell differentiation;GO:0048514//blood vessel morphogenesis;GO:0016477//cell migration;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0051146//striated muscle cell differentiation;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization;GO:0034332//adherens junction organization;GO:0043410//positive regulation of MAPK cascade;GO:0051149//positive regulation of muscle cell differentiation;GO:0034329//cell junction assembly;GO:0097150//neuronal stem cell maintenance;GO:0090090//negative regulation of canonical Wnt signaling pathway,GO:0008013//beta-catenin binding;GO:0045294//alpha-catenin binding;GO:0045295//gamma-catenin binding;GO:0019903//protein phosphatase binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,K06736//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Cell adhesion molecules (CAMs)
10000,0,181,27,236,714,17,10,0,20,0,53,0,AKT3;v-akt murine thymoma viral oncogene homolog 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0000002//mitochondrial genome maintenance,GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04456//Focal adhesion;VEGF signaling pathway;Glioma;Toxoplasmosis;Osteoclast differentiation;Endometrial cancer;Fc gamma R-mediated phagocytosis;Jak-STAT signaling pathway;HTLV-I infection;Renal cell carcinoma;Epstein-Barr virus infection;ErbB signaling pathway;mTOR signaling pathway;Apoptosis;MAPK signaling pathway;Influenza A;Toll-like receptor signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Dopaminergic synapse;Measles;Hepatitis C;Melanoma;Neurotrophin signaling pathway;Adipocytokine signaling pathway;Non-small cell lung cancer;B cell receptor signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Fc epsilon RI signaling pathway;Tight junction;Chagas disease (American trypanosomiasis);Colorectal cancer;Chronic myeloid leukemia;T cell receptor signaling pathway;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;Prostate cancer;Tuberculosis;Insulin signaling pathway
100009676,0,165,28,161,125,0,0,144,30,0,163,0,ZBTB11-AS1;ZBTB11 antisense RNA 1,-,-,-,-
10001,0,0,0,7,7,0,70,0,25,0,0,0,MED6;mediator complex subunit 6,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016592//mediator complex;GO:0016020//membrane,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression,GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003713//transcription coactivator activity,-
10002,0,0,0,0,0,24,22,3,30,6,0,0,"NR2E3;nuclear receptor subfamily 2, group E, member 3",GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0007602//phototransduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0045872//positive regulation of rhodopsin gene expression;GO:0042462//eye photoreceptor cell development;GO:0007601//visual perception;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0060041//retina development in camera-type eye;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,-
100033413,0,0,0,0,0,0,0,0,1,0,0,0,"SNORD116-1;small nucleolar RNA, C/D box 116-1",-,-,-,-
100033440,0,0,0,0,0,0,0,0,8,0,0,0,"SNORD115-3;small nucleolar RNA, C/D box 115-3",-,-,-,-
100033441,0,0,0,0,0,0,1,0,0,0,0,0,"SNORD115-4;small nucleolar RNA, C/D box 115-4",-,-,-,-
100033445,0,0,0,0,0,0,0,0,21,0,0,0,"SNORD115-8;small nucleolar RNA, C/D box 115-8",-,-,-,-
100033451,0,0,0,0,0,10,0,0,0,0,0,0,"SNORD115-14;small nucleolar RNA, C/D box 115-14",-,-,-,-
100033812,0,0,0,0,0,0,0,0,12,0,0,0,"SNORD115-38;small nucleolar RNA, C/D box 115-38",-,-,-,-
100033814,0,0,0,0,0,0,0,0,14,0,0,0,"SNORD115-40;small nucleolar RNA, C/D box 115-40",-,-,-,-
100033822,3,0,0,0,0,0,0,0,0,0,0,0,"SNORD115-48;small nucleolar RNA, C/D box 115-48",-,-,-,-
100034743,3,0,0,0,0,0,0,0,1,0,0,0,PDZK1P2;PDZ domain containing 1 pseudogene 2,-,-,-,-
100037417,10,1091,325,327,1138,0,23,120,116,1,2037,1,DDTL;D-dopachrome tautomerase-like,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0016829//lyase activity,-
10004,0,0,0,0,0,0,0,0,21,0,0,0,NAALADL1;N-acetylated alpha-linked acidic dipeptidase-like 1,GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0004180//carboxypeptidase activity;GO:0046872//metal ion binding;GO:0016805//dipeptidase activity;GO:0008237//metallopeptidase activity,-
100049076,0,0,0,0,0,0,1,0,0,0,0,2,"GUSBP9;glucuronidase, beta pseudogene 9",-,-,-,K01195//Starch and sucrose metabolism;Lysosome;Drug metabolism - other enzymes;Porphyrin and chlorophyll metabolism;Pentose and glucuronate interconversions;Metabolic pathways;Glycosaminoglycan degradation
10005,0,26,0,45,34,0,0,0,0,0,40,0,ACOT8;acyl-CoA thioesterase 8,GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion,GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0016032//viral process;GO:0044255//cellular lipid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0044281//small molecule metabolic process;GO:0043649//dicarboxylic acid catabolic process;GO:0016559//peroxisome fission;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0036109//alpha-linolenic acid metabolic process,GO:0005515//protein binding;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0033882//choloyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005102//receptor binding;GO:0047617//acyl-CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity,K11992//Peroxisome;Metabolic pathways;Primary bile acid biosynthesis
10006,0,30,0,35,93,0,0,61,18,12,0,0,ABI1;abl-interactor 1,GO:0045211//postsynaptic membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0030175//filopodium;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0030426//growth cone;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005634//nucleus,GO:0001756//somitogenesis;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0072673//lamellipodium morphogenesis;GO:0045087//innate immune response;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0008154//actin polymerization or depolymerization;GO:0006928//cellular component movement;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035855//megakaryocyte development;GO:0008285//negative regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0008092//cytoskeletal protein binding;GO:0030296//protein tyrosine kinase activator activity;GO:0032403//protein complex binding;GO:0005515//protein binding,K05751//Regulation of actin cytoskeleton
10007,12,0,0,18,32,0,0,0,0,0,2,0,GNPDA1;glucosamine-6-phosphate deaminase 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0007338//single fertilization;GO:0006044//N-acetylglucosamine metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006043//glucosamine catabolic process,GO:0004342//glucosamine-6-phosphate deaminase activity;GO:0016787//hydrolase activity,K02564//Metabolic pathways;ABC transporters;Two-component system;Lipopolysaccharide biosynthesis;Ribosome;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
10008,0,0,0,0,0,0,0,0,8,0,32,0,"KCNE3;potassium voltage-gated channel, Isk-related family, member 3",GO:0016021//integral component of membrane,GO:0043266//regulation of potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005249//voltage-gated potassium channel activity;GO:0015459//potassium channel regulator activity,K04897//Protein digestion and absorption
10009,122,8,0,62,212,9,0,0,64,0,0,0,ZBTB33;zinc finger and BTB domain containing 33,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0016055//Wnt signaling pathway",GO:0008327//methyl-CpG binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
100093630,0,0,0,28,27,19,8,0,0,0,0,0,SNHG8;small nucleolar RNA host gene 8 (non-protein coding),-,-,-,-
1001,0,0,0,0,0,15,67,5,31,0,43,0,"CDH3;cadherin 3, type 1, P-cadherin (placental)",GO:0005913//cell-cell adherens junction;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0031424//keratinization;GO:0001895//retina homeostasis;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0051796//negative regulation of catagen;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0007601//visual perception;GO:0010838//positive regulation of keratinocyte proliferation;GO:0048023//positive regulation of melanin biosynthetic process;GO:1902910//positive regulation of melanosome transport;GO:0034329//cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0010628//positive regulation of gene expression;GO:0060070//canonical Wnt signaling pathway;GO:0042060//wound healing;GO:0034332//adherens junction organization;GO:0045216//cell-cell junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0032773//positive regulation of monophenol monooxygenase activity;GO:0042493//response to drug;GO:0060901//regulation of hair cycle by canonical Wnt signaling pathway,GO:0005509//calcium ion binding,K06796//Cell adhesion molecules (CAMs)
10010,0,0,0,0,37,12,22,0,1,0,0,0,TANK;TRAF family member-associated NFKB activator,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0031625//ubiquitin protein ligase binding,K12650//RIG-I-like receptor signaling pathway
100101266,0,0,0,0,0,0,18,0,19,0,6,0,HAVCR1P1;hepatitis A virus cellular receptor 1 pseudogene 1,-,-,-,-
100101267,0,0,0,0,33,0,22,0,65,0,2,0,POM121C;POM121 transmembrane nucleoporin C,GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005643//nuclear pore,GO:0015031//protein transport;GO:0051028//mRNA transport,GO:0005515//protein binding,K14316//RNA transport
100101467,0,30,0,0,107,0,0,0,12,0,12,0,ZSCAN30;zinc finger and SCAN domain containing 30,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
100101938,36,0,0,0,0,0,21,0,49,0,0,0,ANKRD26P3;ankyrin repeat domain 26 pseudogene 3,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
10011,11,1,20,6,8,0,13,96,7,0,0,0,SRA1;steroid receptor RNA activator 1,GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0005886//plasma membrane;GO:0031252//cell leading edge;GO:0015630//microtubule cytoskeleton;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0045171//intercellular bridge,"GO:2000273//positive regulation of receptor activity;GO:0008283//cell proliferation;GO:0042981//regulation of apoptotic process;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006915//apoptotic process",GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0010861//thyroid hormone receptor activator activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,-
100113389,0,0,0,0,0,0,2,0,0,0,0,0,"SNORD127;small nucleolar RNA, C/D box 127",-,-,-,-
100113407,0,21,1,7,13,37,45,25,20,0,2,0,TMEM170B;transmembrane protein 170B,GO:0016021//integral component of membrane,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction
100124533,0,0,0,0,0,0,17,0,0,0,0,0,SCARNA27;small Cajal body-specific RNA 27,-,-,-,-
100124534,0,0,0,0,0,0,0,29,0,0,0,0,"SNORA84;small nucleolar RNA, H/ACA box 84",-,-,-,-
100124536,0,0,0,0,0,0,0,0,6,0,0,0,"SNORA38B;small nucleolar RNA, H/ACA box 38B",-,-,-,-
100124537,0,0,0,0,0,0,0,0,0,0,7,0,"SNORA70B;small nucleolar RNA, H/ACA box 70B",-,-,-,-
100124700,85,0,0,0,0,0,0,0,4,0,0,0,HOTAIR;HOX transcript antisense RNA,-,-,-,-
100125288,17,0,0,0,0,0,0,0,0,0,0,0,"ZGLP1;zinc finger, GATA-like protein 1",GO:0005634//nucleus,"GO:0007283//spermatogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048599//oocyte development;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding,-
100126296,0,0,0,0,0,0,7,0,0,0,0,0,MIR298;microRNA 298,-,-,-,-
100126299,0,0,0,0,0,0,11,0,0,0,0,0,VTRNA2-1;vault RNA 2-1,-,-,-,-
100126316,0,0,0,0,0,0,0,0,10,0,0,0,MIR873;microRNA 873,-,-,-,-
100126318,0,0,0,0,0,0,0,0,0,0,6,0,MIR301B;microRNA 301b,-,-,-,-
100126335,0,0,0,0,0,21,0,74,0,0,0,0,MIR543;microRNA 543,-,-,-,-
100126342,0,0,0,0,0,0,0,0,15,0,0,0,MIR892A;microRNA 892a,-,-,-,-
100126349,0,0,0,0,0,0,0,0,0,0,6,0,MIR921;microRNA 921,-,-,-,-
100126780,0,0,0,0,0,0,0,0,4,0,0,0,SNAR-G1;small ILF3/NF90-associated RNA G1,-,-,-,-
100126784,0,0,0,6,4,0,0,0,6,0,0,0,LOC100126784;uncharacterized LOC100126784,-,-,-,-
100127206,0,0,0,0,0,0,1,0,0,0,0,0,KIAA1024L;KIAA1024-like,GO:0016021//integral component of membrane,-,-,-
100127889,0,0,0,0,2,0,0,0,5,0,0,0,C10orf131;chromosome 10 open reading frame 131,-,-,-,-
100127983,0,0,0,0,0,0,0,0,2,0,0,0,C8orf88;chromosome 8 open reading frame 88,-,-,-,-
100128006,0,0,0,0,6,0,0,0,0,221,9,0,LOC100128006;uncharacterized LOC100128006,-,-,-,K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
100128023,0,0,0,0,0,0,0,0,0,0,10,0,DPPA2P3;developmental pluripotency associated 2 pseudogene 3,-,-,-,-
100128055,0,204,53,81,342,12,0,216,59,0,234,0,SMARCA5-AS1;SMARCA5 antisense RNA 1,-,-,-,-
100128076,0,0,0,0,13,0,19,0,6,0,1,0,LOC100128076;protein tyrosine phosphatase pseudogene,-,-,-,-
100128124,0,0,0,0,0,0,1,0,9,0,0,0,HGC6.3;uncharacterized LOC100128124,-,-,-,K12826//Spliceosome
100128164,0,0,0,0,0,10,0,0,29,0,8,0,LOC100128164;four and a half LIM domains 1 pseudogene,-,-,-,-
100128285,26,0,0,0,0,7,0,45,5,105,0,0,DNM1P35;DNM1 pseudogene 35,-,-,-,K01528//Bacterial invasion of epithelial cells;Endocytosis;Synaptic vesicle cycle;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption
100128327,0,0,0,0,0,15,0,0,28,0,0,0,TRAPPC3L;trafficking protein particle complex 3-like,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0016192//vesicle-mediated transport,-,-
100128338,93,0,0,8,53,4,0,57,42,37,0,0,FAM83H-AS1;FAM83H antisense RNA 1 (head to head),-,-,-,K11447//Transcriptional misregulation in cancer
100128361,0,24,0,13,53,0,0,0,0,0,91,0,LOC100128361;uncharacterized LOC100128361,-,-,-,K10572//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
100128378,0,0,0,0,0,8,42,0,0,0,7,0,LINC00696;long intergenic non-protein coding RNA 696,-,-,-,-
100128385,1,0,0,0,0,9,2,0,11,0,0,0,"FAM225B;family with sequence similarity 225, member B (non-protein coding)",-,-,-,-
100128494,165,6959,5595,4851,13465,1,855,17032,3795,3918,29182,736,LOC100128494;uncharacterized LOC100128494,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
100128553,0,1,99,77,5,0,44,6,2,0,62,0,"CTAGE4;CTAGE family, member 4",GO:0016021//integral component of membrane,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
100128569,0,76,2,31,42,0,0,195,0,0,10,0,C19orf71;chromosome 19 open reading frame 71,-,-,-,-
100128573,0,0,0,0,0,0,0,0,0,137,0,0,LOC100128573;uncharacterized LOC100128573,-,-,-,K11447//Transcriptional misregulation in cancer;K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway
100128627,0,0,0,0,0,0,0,0,18,0,0,0,CDC42P3;cell division cycle 42 pseudogene 3,-,-,-,K04393//Salmonella infection;Pancreatic cancer;Endocytosis;MAPK signaling pathway - yeast;Axon guidance;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection;Adherens junction;MAPK signaling pathway;T cell receptor signaling pathway;Leukocyte transendothelial migration;Shigellosis;Fc gamma R-mediated phagocytosis;Bacterial invasion of epithelial cells;Tight junction;Focal adhesion;VEGF signaling pathway;Pathogenic Escherichia coli infection;Regulation of actin cytoskeleton;Neurotrophin signaling pathway
100128640,0,0,0,0,0,17,0,0,17,0,0,0,ACVR2B-AS1;ACVR2B antisense RNA 1,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
100128675,0,114,0,34,43,14,0,116,50,0,226,0,HPN-AS1;HPN antisense RNA 1,-,-,-,K09057//Circadian rhythm - fly;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion
100128682,0,0,0,0,0,0,0,0,22,0,0,235,LOC100128682;uncharacterized LOC100128682,-,-,-,K11447//Transcriptional misregulation in cancer
100128731,0,1,41,23,70,0,0,0,0,0,25,0,OST4;oligosaccharyltransferase 4 homolog (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,K13355//Peroxisome
100128770,0,100,26,78,111,33,52,1426,413,1,559,0,LOC100128770;uncharacterized LOC100128770,-,-,-,-
100128782,0,72,0,42,189,0,35,148,0,0,163,0,LINC00476;long intergenic non-protein coding RNA 476,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
100128788,0,0,0,0,0,0,0,0,0,0,1,0,SRRM2-AS1;SRRM2 antisense RNA 1,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
100128811,0,57,0,3,0,7,0,72,13,0,12,0,GPR158-AS1;GPR158 antisense RNA 1,-,-,-,-
100128881,0,223,151,94,171,10,67,649,0,1,452,0,VPS9D1-AS1;VPS9D1 antisense RNA 1,-,-,-,-
100128890,0,0,0,0,0,10,0,0,0,0,0,0,"FAM66B;family with sequence similarity 66, member B",-,-,-,-
100128927,0,1,25,6,3,0,9,76,10,0,13,0,ZBTB42;zinc finger and BTB domain containing 42,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K10500//Transcriptional misregulation in cancer;Cell cycle
100128946,0,0,0,0,0,14,40,0,52,0,0,0,LINC01310;long intergenic non-protein coding RNA 1310,-,-,-,-
100128977,0,0,0,0,0,0,0,0,1,0,0,0,MAPT-AS1;MAPT antisense RNA 1,-,-,-,-
100129034,0,898,323,942,1393,26,138,339,90,255,1194,418,LOC100129034;uncharacterized LOC100129034,-,-,-,K02739//Proteasome
100129046,0,0,0,0,10,0,0,0,0,0,2,0,LOC100129046;uncharacterized LOC100129046,-,-,-,-
100129094,0,0,0,0,0,0,0,0,6,0,0,0,BTNL10;butyrophilin-like 10,GO:0016021//integral component of membrane,-,-,-
100129148,1,145,129,217,477,0,0,187,14,85,452,0,LOC100129148;uncharacterized LOC100129148,-,-,-,-
100129196,0,0,0,0,0,0,0,0,0,174,0,0,MATN1-AS1;MATN1 antisense RNA 1,-,-,-,K06238//Focal adhesion;Protein digestion and absorption;ECM-receptor interaction
100129250,0,18,22,36,15,20,30,113,43,0,32,0,TOPORS-AS1;TOPORS antisense RNA 1,-,-,-,K02311//Apoptosis
100129269,0,0,0,0,0,0,0,0,0,0,21,0,LINC01160;long intergenic non-protein coding RNA 1160,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
100129271,162,0,0,0,0,0,0,0,14,0,0,0,C1orf68;chromosome 1 open reading frame 68,GO:0070062//extracellular vesicular exosome,GO:0008544//epidermis development,-,-
100129354,0,0,0,0,0,0,0,5,19,0,0,0,"NRADDP;neurotrophin receptor associated death domain, pseudogene",-,-,-,K02583//Cytokine-cytokine receptor interaction;Neurotrophin signaling pathway;Transcriptional misregulation in cancer
100129361,0,46,3,66,282,1,0,84,38,0,91,0,LOC100129361;chromosome X open reading frame 69-like,-,-,-,-
100129385,0,0,0,0,0,0,0,0,0,0,1,0,C9orf92;chromosome 9 open reading frame 92,-,-,-,-
100129405,107,51,97,95,160,1,34,47,93,0,89,3,"MSTO2P;misato family member 2, pseudogene",-,-,-,-
100129424,0,0,0,0,0,1,0,101,21,0,0,0,RPL19P12;ribosomal protein L19 pseudogene 12,-,-,-,K02885//Ribosome
100129427,0,0,0,0,0,15,0,56,39,1,5,0,DDC-AS1;DDC antisense RNA 1,-,-,-,K01593//Amphetamine addiction;Tyrosine metabolism;Metabolic pathways;Phenylalanine metabolism;Cocaine addiction;Dopaminergic synapse;Isoquinoline alkaloid biosynthesis;Histidine metabolism;Biosynthesis of secondary metabolites;Serotonergic synapse;Alcoholism;Betalain biosynthesis;Tryptophan metabolism
100129460,0,4,0,0,8,0,0,0,0,0,0,0,DPY19L1P1;DPY19L1 pseudogene 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption
100129520,0,0,0,0,0,17,0,0,8,13,0,0,LOC100129520;testis expressed sequence 13-like,-,-,-,K13911//Salivary secretion
100129534,0,0,0,0,0,0,0,0,16,0,0,0,LOC100129534;small nuclear ribonucleoprotein polypeptide N pseudogene,-,-,-,-
100129543,0,0,0,0,0,17,0,0,0,0,0,0,ZNF730;zinc finger protein 730,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
100129583,0,0,0,0,10,0,0,0,0,0,0,0,"FAM47E;family with sequence similarity 47, member E",-,-,-,-
100129654,0,0,0,0,0,12,0,0,0,0,6,0,TCF24;transcription factor 24,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
100129669,0,0,0,0,0,10,0,0,13,0,0,0,IZUMO3;IZUMO family member 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,GO:0042803//protein homodimerization activity,-
100129697,79,0,0,0,0,0,0,0,9,0,0,0,LOC100129697;uncharacterized LOC100129697,-,-,-,-
100129792,0,536,458,1218,898,7,15,0,65,0,527,0,CCDC152;coiled-coil domain containing 152,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
100129842,28,0,0,34,49,0,32,0,50,0,2,0,ZNF737;zinc finger protein 737,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
100129845,0,82,349,111,19,14,1,384,135,1,194,0,PCOLCE-AS1;PCOLCE antisense RNA 1,-,-,-,-
100129858,0,0,0,0,0,24,0,0,9,0,0,0,SCOC-AS1;SCOC antisense RNA 1,-,-,-,-
100129917,0,0,0,0,0,0,0,0,11,0,0,0,LOC100129917;uncharacterized LOC100129917,-,-,-,K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
100129924,0,0,0,0,0,0,0,0,12,0,11,0,LOC100129924;uncharacterized LOC100129924,-,-,-,K01345//Protein digestion and absorption;Pancreatic secretion
100129940,0,0,0,0,0,29,1,0,24,0,0,0,LOC100129940;uncharacterized LOC100129940,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K09057//Circadian rhythm - fly
100129973,0,140,64,382,386,16,0,181,14,0,406,0,LOC100129973;uncharacterized LOC100129973,-,-,-,-
10013,0,7,0,0,8,18,0,0,15,0,19,0,HDAC6;histone deacetylase 6,GO:0030424//axon;GO:0043204//perikaryon;GO:0005875//microtubule associated complex;GO:0005634//nucleus;GO:0005901//caveola;GO:0000118//histone deacetylase complex;GO:0030425//dendrite;GO:0005881//cytoplasmic microtubule;GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0030286//dynein complex;GO:0005829//cytosol;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0016234//inclusion body;GO:0016235//aggresome,"GO:0071218//cellular response to misfolded protein;GO:0070933//histone H4 deacetylation;GO:0016575//histone deacetylation;GO:0070842//aggresome assembly;GO:0006886//intracellular protein transport;GO:0032418//lysosome localization;GO:0060765//regulation of androgen receptor signaling pathway;GO:0090035//positive regulation of chaperone-mediated protein complex assembly;GO:0016236//macroautophagy;GO:0070846//Hsp90 deacetylation;GO:0070845//polyubiquitinated misfolded protein transport;GO:0006351//transcription, DNA-templated;GO:0000209//protein polyubiquitination;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0009636//response to toxic substance;GO:0043242//negative regulation of protein complex disassembly;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0007026//negative regulation of microtubule depolymerization;GO:0006476//protein deacetylation;GO:0070848//response to growth factor;GO:0010634//positive regulation of epithelial cell migration;GO:0090042//tubulin deacetylation;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051354//negative regulation of oxidoreductase activity;GO:0070201//regulation of establishment of protein localization;GO:1901300//positive regulation of hydrogen peroxide-mediated programmed cell death;GO:0010870//positive regulation of receptor biosynthetic process;GO:0040029//regulation of gene expression, epigenetic;GO:0060632//regulation of microtubule-based movement;GO:0070301//cellular response to hydrogen peroxide;GO:0051788//response to misfolded protein;GO:0070932//histone H3 deacetylation;GO:0009967//positive regulation of signal transduction;GO:0010469//regulation of receptor activity;GO:0043241//protein complex disassembly;GO:0034983//peptidyl-lysine deacetylation;GO:0045861//negative regulation of proteolysis;GO:0010033//response to organic substance",GO:0004407//histone deacetylase activity;GO:0051879//Hsp90 protein binding;GO:0001047//core promoter binding;GO:0003779//actin binding;GO:0042903//tubulin deacetylase activity;GO:0019899//enzyme binding;GO:0008270//zinc ion binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0005515//protein binding;GO:0048156//tau protein binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0070840//dynein complex binding;GO:0008017//microtubule binding;GO:0042826//histone deacetylase binding;GO:0031593//polyubiquitin binding;GO:0008013//beta-catenin binding;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific),K11407//Alcoholism
100130015,71,336,168,215,238,1,21,629,43,1,539,0,"URAHP;urate (hydroxyiso-) hydrolase, pseudogene",-,-,-,K07127//Microbial metabolism in diverse environments;Metabolic pathways;Purine metabolism
100130148,0,0,0,0,0,0,0,0,1,0,0,0,MAPT-IT1;MAPT intronic transcript 1 (non-protein coding),-,-,-,-
100130238,0,0,0,0,0,0,0,1,28,0,0,0,LOC100130238;uncharacterized LOC100130238,-,-,-,-
100130264,0,0,47,0,0,0,5,0,10,23,0,0,LOC100130264;uncharacterized LOC100130264,-,-,-,-
100130274,0,0,0,0,0,4,3,0,0,0,0,0,CCDC166;coiled-coil domain containing 166,-,-,-,-
100130301,0,0,0,0,0,11,0,0,4,0,0,0,LOC100130301;uncharacterized LOC100130301,-,-,-,-
100130302,0,0,0,0,0,0,0,0,18,7,0,0,SUPT20HL1;suppressor of Ty 20 homolog (S. cerevisiae)-like 1,GO:0000124//SAGA complex,GO:2001141//regulation of RNA biosynthetic process,GO:0003712//transcription cofactor activity,-
100130311,0,0,0,10,17,0,13,0,11,0,0,0,C17orf107;chromosome 17 open reading frame 107,-,-,-,K04817//Neuroactive ligand-receptor interaction
100130331,1,0,0,0,0,0,18,57,23,142,0,0,"LOC100130331;POTE ankyrin domain family, member F pseudogene",-,-,-,K05692//Influenza A;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phototransduction - fly;Adherens junction;Viral myocarditis;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM)
100130348,0,31,0,0,0,0,0,0,21,0,0,1,TMEM262;transmembrane protein 262,GO:0016021//integral component of membrane,-,-,-
100130357,0,0,0,0,0,0,0,8,9,0,9,0,LOC100130357;uncharacterized LOC100130357,-,-,-,K03914//Regulation of actin cytoskeleton;Endocytosis;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Calcium signaling pathway
100130386,52,0,0,3,0,0,0,0,0,191,8,0,LINC00552;long intergenic non-protein coding RNA 552,-,-,-,-
100130418,160,0,0,0,0,0,0,0,0,0,0,0,"CECR7;cat eye syndrome chromosome region, candidate 7 (non-protein coding)",-,-,-,K01896//Butanoate metabolism;Metabolic pathways;Lipoic acid metabolism
100130449,0,0,0,0,0,0,0,0,0,179,0,0,PP14571;uncharacterized LOC100130449,-,-,-,-
100130480,0,0,0,0,0,0,9,0,6,0,0,0,LINC01387;long intergenic non-protein coding RNA 1387,-,-,-,-
100130519,0,0,0,0,22,0,0,70,8,0,0,0,TMEM221;transmembrane protein 221,GO:0016021//integral component of membrane,-,-,-
100130539,0,0,0,0,0,0,0,0,9,0,0,0,LOC100130539;uncharacterized LOC100130539,-,-,-,-
100130613,0,0,0,0,0,0,0,0,3,0,0,0,PRR32;proline rich 32,-,-,-,-
100130673,0,0,0,0,0,0,0,116,0,0,0,0,LOC100130673;phosphoribosyl pyrophosphate synthetase 2 pseudogene,-,-,-,K00948//Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Thiamine metabolism;Microbial metabolism in diverse environments;Oxidative phosphorylation;Pentose phosphate pathway
100130705,0,0,0,0,0,0,27,0,0,0,5,0,LOC100130705;uncharacterized LOC100130705,-,-,-,-
100130733,0,0,0,0,0,18,0,0,0,0,0,0,LRRC70;leucine rich repeat containing 70,GO:0016021//integral component of membrane,-,-,K06248//ECM-receptor interaction;Focal adhesion
100130742,0,0,0,0,0,13,0,0,5,0,0,0,LRRC69;leucine rich repeat containing 69,-,-,-,K12796//NOD-like receptor signaling pathway;K01768//Purine metabolism;Meiosis - yeast
100130771,0,41,5,105,97,0,0,0,0,0,69,0,EFCAB10;EF-hand calcium binding domain 10,-,-,GO:0005509//calcium ion binding,-
100130776,0,0,5,0,0,0,11,0,26,0,0,0,AGAP2-AS1;AGAP2 antisense RNA 1,-,-,-,K12491//Endocytosis
100130827,51,0,0,0,0,0,0,0,12,0,6,0,"SBK3;SH3 domain binding kinase family, member 3",-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
100130849,0,0,0,0,0,0,24,0,10,0,0,0,"LOC100130849;phosphorylase kinase, gamma 1 (muscle) pseudogene",-,-,-,K00871//Insulin signaling pathway;Calcium signaling pathway
100130855,0,61,1,95,141,0,0,0,0,0,111,0,USP3-AS1;USP3 antisense RNA 1,-,-,-,-
100130890,0,35,1,0,17,0,0,0,0,0,0,0,TSTD3;thiosulfate sulfurtransferase (rhodanese)-like domain containing 3,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
100130894,1,43,32,100,124,0,22,444,53,1,278,0,VAC14-AS1;VAC14 antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K01539//Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K01191//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Pyrimidine metabolism;Cyanoamino acid metabolism;Sphingolipid metabolism;Glycerolipid metabolism;Other glycan degradation;Galactose metabolism;Metabolic pathways
100130899,0,19,0,26,2,0,0,0,14,0,0,0,LOC100130899;uncharacterized LOC100130899,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100130958,0,0,0,0,0,0,0,0,0,0,14,0,SYCE1L;synaptonemal complex central element protein 1-like,GO:0000795//synaptonemal complex,GO:0007130//synaptonemal complex assembly,-,-
100130967,0,0,0,0,0,0,0,0,23,0,0,0,C6orf99;chromosome 6 open reading frame 99,-,-,-,-
100130988,0,0,0,0,0,7,0,0,0,0,0,0,C7orf72;chromosome 7 open reading frame 72,-,-,-,-
100131017,0,0,9,0,4,36,1,1,32,0,16,0,ZNF316;zinc finger protein 316,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100131067,0,0,0,0,0,0,28,9,17,0,0,0,CKMT2-AS1;CKMT2 antisense RNA 1,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways
100131094,1,203,182,179,96,0,0,210,33,0,370,313,DPP9-AS1;DPP9 antisense RNA 1,-,-,-,-
100131137,0,0,0,0,0,1,16,0,0,0,0,0,BSPH1;binder of sperm protein homolog 1,GO:0005576//extracellular region;GO:0009986//cell surface,GO:0048240//sperm capacitation;GO:0007338//single fertilization,GO:0008201//heparin binding,K05717//Focal adhesion;Amoebiasis;Small cell lung cancer;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;ECM-receptor interaction;Pathways in cancer;K01398//Leukocyte transendothelial migration;Bladder cancer;GnRH signaling pathway;Pathways in cancer
100131176,0,0,0,0,0,0,0,0,2,0,0,0,WDR86-AS1;WDR86 antisense RNA 1,-,-,-,-
100131187,0,14,1,7,4,0,0,1,7,0,8,0,TSTD1;thiosulfate sulfurtransferase (rhodanese)-like domain containing 1,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,-,-,K01011//Metabolic pathways;Cysteine and methionine metabolism;Sulfur relay system
100131193,0,85,111,31,50,0,40,205,45,0,113,0,CCDC183-AS1;CCDC183 antisense RNA 1,-,-,-,-
100131211,0,0,0,0,0,0,3,0,21,222,0,1,TMEM194B;transmembrane protein 194B,GO:0016021//integral component of membrane,-,-,-
100131213,0,0,0,0,0,0,0,0,4,0,0,0,ZNF503-AS2;ZNF503 antisense RNA 2,-,-,-,-
100131244,0,0,0,0,0,0,0,0,19,0,0,0,ANKRD63;ankyrin repeat domain 63,-,-,-,-
100131257,0,0,0,0,0,28,63,1,86,95,2,0,LOC100131257;zinc finger protein 655 pseudogene,-,-,-,-
100131303,0,0,0,0,0,0,0,0,0,0,9,0,LOC100131303;uncharacterized LOC100131303,-,-,-,-
100131315,0,0,0,0,0,0,0,0,0,0,40,0,LOC100131315;uncharacterized LOC100131315,-,-,-,-
100131378,0,0,0,0,0,0,0,0,37,0,0,0,C11orf91;chromosome 11 open reading frame 91,-,-,-,K04008//Hematopoietic cell lineage;Complement and coagulation cascades
100131390,0,0,0,0,0,0,0,1,0,322,10,0,SP9;Sp9 transcription factor,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030326//embryonic limb morphogenesis;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
100131439,0,0,0,0,9,0,0,56,26,0,0,0,CD300LD;CD300 molecule-like family member d,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0002376//immune system process,GO:0005515//protein binding,-
100131454,3,0,26,0,10,13,32,0,15,0,38,0,"DBIL5P;diazepam binding inhibitor-like 5, pseudogene",-,-,-,K08762//PPAR signaling pathway
100131496,0,0,0,0,14,0,0,79,6,0,0,0,LOC100131496;uncharacterized LOC100131496,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100131539,0,0,0,0,0,0,0,0,14,0,0,0,ZNF705E;zinc finger protein 705E,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100131626,0,49,5,56,12,0,0,0,29,0,63,0,LOC100131626;uncharacterized LOC100131626,-,-,-,K10596//Ubiquitin mediated proteolysis
100131691,0,19,0,38,43,0,15,69,29,0,35,0,LOC100131691;uncharacterized LOC100131691,-,-,-,K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
100131755,0,0,0,0,7,37,0,37,70,1,4,0,"ARMCX4;armadillo repeat containing, X-linked 4",GO:0016021//integral component of membrane,-,-,K01352//Neuroactive ligand-receptor interaction;K12465//Neurotrophin signaling pathway;K05185//GABAergic synapse;Morphine addiction;Nicotine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
100131801,0,0,0,9,13,0,5,0,0,0,0,0,PET100;PET100 homolog (S. cerevisiae),GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,-
100131825,19,0,1,13,0,13,0,86,1,134,1,0,CADM3-AS1;CADM3 antisense RNA 1,-,-,-,K06780//Cell adhesion molecules (CAMs)
100131827,0,47,1,36,8,0,0,0,0,0,0,0,ZNF717;zinc finger protein 717,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100131897,0,0,0,0,0,0,47,76,10,0,0,1,"FAM196B;family with sequence similarity 196, member B",-,-,-,-
100131980,0,0,0,0,0,22,0,0,17,0,5,0,ZNF705G;zinc finger protein 705G,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
100131998,0,32,1,7,34,0,5,1,30,0,16,0,RRN3P3;RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3,-,-,-,-
100132057,0,0,3,8,0,2,0,0,0,0,1,0,LOC100132057;phosphodiesterase 4D interacting protein pseudogene,-,-,-,-
100132074,0,0,23,0,0,0,0,0,46,0,0,0,FOXO6;forkhead box O6,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K07201//Prostate cancer;Transcriptional misregulation in cancer;Pathways in cancer;Insulin signaling pathway
100132103,0,0,0,0,0,0,0,0,0,2,0,0,"FAM66E;family with sequence similarity 66, member E",-,-,-,-
100132111,0,0,0,0,19,0,0,0,0,0,3,0,LOC100132111;uncharacterized LOC100132111,-,-,-,-
100132163,0,72,1,36,72,0,32,0,11,0,126,319,PHKA2-AS1;PHKA2 antisense RNA 1,-,-,-,K07190//Insulin signaling pathway;Calcium signaling pathway
100132174,0,0,0,0,0,12,27,0,3,0,0,0,LOC100132174;uncharacterized LOC100132174,-,-,-,-
100132215,0,35,110,48,33,0,0,321,11,1,86,0,LOC100132215;uncharacterized LOC100132215,-,-,-,-
100132247,1,0,0,0,0,11,1,6,1,1,0,0,"NPIPB5;nuclear pore complex interacting protein family, member B5",-,-,-,K01896//Butanoate metabolism;Lipoic acid metabolism;Metabolic pathways;K10413//Vasopressin-regulated water reabsorption;Phagosome;Salmonella infection
100132285,0,0,0,0,0,0,2,0,14,0,0,0,"KIR2DS2;killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0006955//immune response;GO:0045087//innate immune response;GO:0050776//regulation of immune response,GO:0004888//transmembrane signaling receptor activity,K07982//Natural killer cell mediated cytotoxicity;Antigen processing and presentation;K07980//Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Antigen processing and presentation;K07981//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
100132288,0,0,0,0,1,0,0,0,0,0,0,0,TEKT4P2;tektin 4 pseudogene 2,-,-,-,K04688//TGF-beta signaling pathway;ErbB signaling pathway;Fc gamma R-mediated phagocytosis;mTOR signaling pathway;Acute myeloid leukemia;Insulin signaling pathway
100132341,0,0,0,0,0,0,7,0,24,0,0,0,CLUHP3;clustered mitochondria (cluA/CLU1) homolog pseudogene 3,-,-,-,-
100132386,0,0,0,0,0,0,31,0,12,0,0,0,KRTAP4-9;keratin associated protein 4-9,GO:0045095//keratin filament,GO:0007568//aging;GO:0042633//hair cycle,-,-
100132396,0,0,0,0,0,0,0,0,9,0,0,0,ZNF705B;zinc finger protein 705B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100132403,0,0,0,0,0,0,0,56,0,0,0,0,"FAM157B;family with sequence similarity 157, member B",-,-,-,-
100132417,4,37,0,11,1,0,0,0,0,0,14,0,"FCGR1C;Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0002376//immune system process,GO:0019864//IgG binding,K06498//Systemic lupus erythematosus;Leishmaniasis;Osteoclast differentiation;Staphylococcus aureus infection;Hematopoietic cell lineage;Transcriptional misregulation in cancer;Fc gamma R-mediated phagocytosis;Tuberculosis;Phagosome
100132526,0,0,0,0,0,3,0,26,17,294,0,0,"FGD5P1;FYVE, RhoGEF and PH domain containing 5 pseudogene 1",-,-,-,-
100132541,0,0,0,0,0,2,1,0,12,0,0,0,GXYLT1P3;glucoside xylosyltransferase 1 pseudogene 3,-,-,-,K13676//Other types of O-glycan biosynthesis
100132594,0,0,0,0,0,0,14,0,14,0,0,0,PGAM1P5;phosphoglycerate mutase 1 pseudogene 5,-,-,-,"K01834//Metabolic pathways;Microbial metabolism in diverse environments;Glycine, serine and threonine metabolism;Glycolysis / Gluconeogenesis;Methane metabolism;Biosynthesis of secondary metabolites"
100132618,0,0,0,11,0,0,0,44,9,0,0,0,ZRANB2-AS1;ZRANB2 antisense RNA 1,-,-,-,K04260//Calcium signaling pathway;Neuroactive ligand-receptor interaction
100132707,93,0,1,2,24,0,0,0,0,0,44,0,PAXIP1OS;PAXIP1 opposite strand,-,-,-,-
100132831,0,0,0,0,0,0,0,0,0,0,22,0,LOC100132831;A20-binding inhibitor of NF-kappaB activation 2 pseudogene,-,-,-,-
100132832,0,0,7,30,0,0,0,0,1,0,0,0,PMS2P9;postmeiotic segregation increased 2 pseudogene 9,-,-,-,K10858//Mismatch repair;Fanconi anemia pathway
100132891,0,0,0,0,0,0,0,0,29,0,13,0,LOC100132891;uncharacterized LOC100132891,-,-,-,-
100132911,131,39,0,45,29,0,20,7,0,0,48,0,DPH3P1;diphthamide biosynthesis 3 pseudogene 1,-,-,GO:0046872//metal ion binding,-
100132916,0,0,0,0,0,0,17,0,20,0,0,0,"FAM159B;family with sequence similarity 159, member B",GO:0016021//integral component of membrane,-,-,-
100132979,0,0,0,0,1,0,0,0,2,15,0,4,"GOLGA8DP;golgin A8 family, member D, pseudogene",GO:0005794//Golgi apparatus,-,-,-
100133077,0,0,0,7,0,12,16,109,38,0,0,0,LOC100133077;uncharacterized LOC100133077,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
100133091,0,56,53,75,182,6,0,0,33,4,543,0,LOC100133091;uncharacterized LOC100133091,-,-,-,K14316//RNA transport
100133121,0,7,1,0,16,0,3,63,8,0,17,0,"FAM27B;family with sequence similarity 27, member B",-,-,-,-
100133161,89,0,0,0,0,0,0,2,3,0,0,0,LINC01001;long intergenic non-protein coding RNA 1001,-,-,-,K10955//Amoebiasis;Vibrio cholerae infection
100133172,4,0,0,0,0,0,0,0,19,0,0,0,"FAM66A;family with sequence similarity 66, member A",-,-,-,-
100133234,0,0,0,0,0,0,15,74,72,0,0,0,SBF1P1;SET binding factor 1 pseudogene 1,-,-,-,-
100133286,107,607,106,459,572,0,50,538,34,1,1030,1,LOC100133286;uncharacterized LOC100133286,-,-,-,K00079//Metabolism of xenobiotics by cytochrome P450;Arachidonic acid metabolism;Metabolic pathways
100133308,0,0,0,0,0,0,1,0,0,0,0,0,RSU1P2;Ras suppressor protein 1 pseudogene 2,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
100133311,0,0,0,51,33,0,93,0,2,0,57,0,HOXA-AS3;HOXA cluster antisense RNA 3,-,-,-,-
100133315,71,0,0,0,0,0,0,0,11,0,0,0,"LOC100133315;transient receptor potential cation channel, subfamily C, member 2-like",GO:0005634//nucleus,GO:0000012//single strand break repair,GO:0003684//damaged DNA binding,-
100133331,0,0,0,0,0,1,0,0,4,0,0,0,LOC100133331;uncharacterized LOC100133331,-,-,-,-
100133545,0,0,0,0,0,0,0,1,0,0,0,0,MRPL23-AS1;MRPL23 antisense RNA 1,-,-,-,-
100133920,3,0,0,0,0,2,0,0,2,0,0,0,LOC100133920;uncharacterized LOC100133920,-,-,-,K13402//Metabolic pathways;One carbon pool by folate
100133941,209,0,21,34,173,0,0,0,0,0,0,0,CD24;CD24 molecule,GO:0009986//cell surface;GO:0016020//membrane;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0043627//response to estrogen;GO:0002237//response to molecule of bacterial origin;GO:0001666//response to hypoxia;GO:0042632//cholesterol homeostasis;GO:0072139//glomerular parietal epithelial cell differentiation;GO:0016055//Wnt signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0030856//regulation of epithelial cell differentiation;GO:0045730//respiratory burst;GO:0016477//cell migration;GO:0007411//axon guidance;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0043408//regulation of MAPK cascade;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0001775//cell activation;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0031295//T cell costimulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042325//regulation of phosphorylation,GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0030296//protein tyrosine kinase activator activity,K11447//Transcriptional misregulation in cancer;K06469//Hematopoietic cell lineage;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
100133991,90,0,0,3,22,0,2,0,32,0,37,1,MAP3K14-AS1;MAP3K14 antisense RNA 1,-,-,-,K04466//NF-kappa B signaling pathway;HTLV-I infection;Intestinal immune network for IgA production;MAPK signaling pathway;T cell receptor signaling pathway;Osteoclast differentiation;Apoptosis;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection
100134391,0,0,0,0,0,0,0,0,25,0,3,0,LOC100134391;uncharacterized LOC100134391,-,-,-,-
100137047,1,0,0,0,1,0,0,0,7,0,0,0,JMJD7;jumonji domain containing 7,-,-,-,K01047//Fc epsilon RI signaling pathway;Long-term depression;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Toxoplasmosis;Arachidonic acid metabolism;Ether lipid metabolism;VEGF signaling pathway;Glycerophospholipid metabolism;GnRH signaling pathway;alpha-Linolenic acid metabolism;Serotonergic synapse;Pancreatic secretion;Vascular smooth muscle contraction;Metabolic pathways;Glutamatergic synapse;Linoleic acid metabolism;MAPK signaling pathway
10014,214,0,31,0,0,30,1,112,38,0,23,0,HDAC5;histone deacetylase 5,GO:0000118//histone deacetylase complex;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0032869//cellular response to insulin stimulus;GO:0006351//transcription, DNA-templated;GO:0040029//regulation of gene expression, epigenetic;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042493//response to drug;GO:0010832//negative regulation of myotube differentiation;GO:0070932//histone H3 deacetylation;GO:0007507//heart development;GO:0042220//response to cocaine;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006342//chromatin silencing;GO:0045668//negative regulation of osteoblast differentiation;GO:0070933//histone H4 deacetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0006338//chromatin remodeling;GO:0033555//multicellular organismal response to stress;GO:0010830//regulation of myotube differentiation;GO:0002076//osteoblast development;GO:0043393//regulation of protein binding;GO:0030183//B cell differentiation;GO:0048742//regulation of skeletal muscle fiber development;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042113//B cell activation;GO:0007219//Notch signaling pathway;GO:0016568//chromatin modification",GO:0001047//core promoter binding;GO:0003714//transcription corepressor activity;GO:0005080//protein kinase C binding;GO:0070491//repressing transcription factor binding;GO:0004407//histone deacetylase activity;GO:0044212//transcription regulatory region DNA binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding,K11406//Epstein-Barr virus infection;Alcoholism
100141515,0,0,0,0,0,0,0,56,0,0,0,0,C17orf99;chromosome 17 open reading frame 99,GO:0005576//extracellular region,-,-,-
100142659,0,0,0,13,10,0,0,0,10,0,8,0,"CTAGE8;CTAGE family, member 8",GO:0016021//integral component of membrane,-,-,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
100144748,51,0,62,0,42,27,0,117,38,97,56,343,"KLLN;killin, p53-regulated DNA replication inhibitor",GO:0005634//nucleus,GO:0007049//cell cycle;GO:0006915//apoptotic process,GO:0003677//DNA binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer
10015,1,176,3,141,444,21,18,241,121,0,102,1,PDCD6IP;programmed cell death 6 interacting protein,GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0042470//melanosome;GO:0001772//immunological synapse;GO:0005815//microtubule organizing center;GO:0005925//focal adhesion;GO:0005829//cytosol,GO:0007049//cell cycle;GO:0015031//protein transport;GO:0019058//viral life cycle;GO:0006915//apoptotic process;GO:0051301//cell division;GO:0016032//viral process,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0048306//calcium-dependent protein binding,K12200//Endocytosis
100151643,0,0,0,0,0,0,0,0,0,57,0,0,KRTAP20-4;keratin associated protein 20-4,-,-,-,-
10016,0,25,0,4,13,0,0,0,9,0,0,0,PDCD6;programmed cell death 6,GO:0031410//cytoplasmic vesicle;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0006508//proteolysis;GO:0051592//response to calcium ion;GO:0097190//apoptotic signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0032007//negative regulation of TOR signaling;GO:0001525//angiogenesis;GO:0006886//intracellular protein transport;GO:0045766//positive regulation of angiogenesis;GO:0051898//negative regulation of protein kinase B signaling;GO:0034605//cellular response to heat;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process,"GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0060090//binding, bridging",K14209//Protein digestion and absorption;K07359//Adipocytokine signaling pathway;Alcoholism;K06264//ECM-receptor interaction;K13510//Metabolic pathways;Glycerophospholipid metabolism;Ether lipid metabolism
100169851,0,0,0,0,0,0,0,0,15,0,0,0,PATE3;prostate and testis expressed 3,GO:0005576//extracellular region,-,-,-
10017,0,0,0,9,0,0,0,0,0,0,35,0,BCL2L10;BCL2-like 10 (apoptosis facilitator),GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0031965//nuclear membrane,GO:0007292//female gamete generation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043066//negative regulation of apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043065//positive regulation of apoptotic process;GO:0007283//spermatogenesis;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K04539//Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling;Cholinergic synapse;Chemokine signaling pathway;Dopaminergic synapse;GABAergic synapse;Morphine addiction;Glutamatergic synapse
100170220,0,0,0,0,0,0,3,0,0,0,0,0,SNAR-E;small ILF3/NF90-associated RNA E,-,-,-,-
100170226,0,0,0,0,0,7,0,0,11,12,0,0,SNAR-C3;small ILF3/NF90-associated RNA C3,-,-,-,-
100170228,0,0,0,0,0,0,0,0,0,0,5,0,SNAR-G2;small ILF3/NF90-associated RNA G2,-,-,-,-
100170229,0,657,206,283,513,0,46,540,135,0,1070,1098,SRRM5;serine/arginine repetitive matrix 5,-,-,-,K12893//Spliceosome;Herpes simplex infection
100170765,0,0,0,0,0,24,37,0,1,0,0,0,ERICH4;glutamate-rich 4,-,-,-,-
100170841,0,0,0,0,1,0,0,17,0,0,0,0,C17orf96;chromosome 17 open reading frame 96,-,GO:0048663//neuron fate commitment,-,K07603//Protein digestion and absorption
10018,75,0,0,39,84,0,31,0,53,0,7,0,BCL2L11;BCL2-like 11 (apoptosis facilitator),GO:0019898//extrinsic component of membrane;GO:0005874//microtubule;GO:0012505//endomembrane system;GO:0097141//BIM-BCL-2 complex;GO:0005741//mitochondrial outer membrane;GO:0097140//BIM-BCL-xl complex;GO:0005829//cytosol,GO:0034976//response to endoplasmic reticulum stress;GO:0045787//positive regulation of cell cycle;GO:0042475//odontogenesis of dentin-containing tooth;GO:0060139//positive regulation of apoptotic process by virus;GO:0007283//spermatogenesis;GO:0097190//apoptotic signaling pathway;GO:0008584//male gonad development;GO:0048070//regulation of developmental pigmentation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043029//T cell homeostasis;GO:0048536//spleen development;GO:0001822//kidney development;GO:0032464//positive regulation of protein homooligomerization;GO:0002262//myeloid cell homeostasis;GO:0060154//cellular process regulating host cell cycle in response to virus;GO:0043525//positive regulation of neuron apoptotic process;GO:0048563//post-embryonic organ morphogenesis;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0007420//brain development;GO:0048066//developmental pigmentation;GO:0006915//apoptotic process;GO:0035148//tube formation;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:0007160//cell-matrix adhesion;GO:0001783//B cell apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0001782//B cell homeostasis;GO:0030879//mammary gland development;GO:0046620//regulation of organ growth;GO:0001701//in utero embryonic development;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0048538//thymus development;GO:0070242//thymocyte apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0043583//ear development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway,GO:0005515//protein binding;GO:0008017//microtubule binding,K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
100188893,0,26,0,13,55,0,0,0,19,0,0,0,TOMM6;translocase of outer mitochondrial membrane 6 homolog (yeast),GO:0005739//mitochondrion;GO:0005742//mitochondrial outer membrane translocase complex,GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion,-,-
100188954,0,70,0,94,91,22,20,6,104,1,219,0,DNMBP-AS1;DNMBP antisense RNA 1,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
10019,39,0,0,4,0,23,16,0,18,157,52,0,SH2B3;SH2B adaptor protein 3,GO:0005829//cytosol,GO:0035556//intracellular signal transduction;GO:0035162//embryonic hemopoiesis;GO:0030154//cell differentiation;GO:0007596//blood coagulation,GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0042301//phosphate ion binding;GO:0032403//protein complex binding,K12459//Neurotrophin signaling pathway
100191040,0,20,0,0,15,0,0,0,8,0,0,0,C2CD4D;C2 calcium-dependent domain containing 4D,-,-,-,K08534//Circadian rhythm - mammal
100192204,0,0,0,0,0,16,0,25,20,0,0,0,PPIAP30;peptidylprolyl isomerase A (cyclophilin A) pseudogene 30,-,-,-,-
100192386,64,0,0,0,0,0,30,0,42,0,19,0,FLJ16779;uncharacterized LOC100192386,-,-,-,K03254//RNA transport
100192420,0,0,0,0,0,0,0,0,28,0,13,0,FLJ41941;uncharacterized LOC100192420,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
1002,0,0,0,0,0,0,0,90,71,0,53,0,"CDH4;cadherin 4, type 1, R-cadherin (retinal)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0045216//cell-cell junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034329//cell junction assembly;GO:0034332//adherens junction organization;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,K06797//Cell adhesion molecules (CAMs)
10020,0,91,1,54,81,29,7,0,14,76,6,0,GNE;glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006045//N-acetylglucosamine biosynthetic process;GO:0006054//N-acetylneuraminate metabolic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0007155//cell adhesion,"GO:0005524//ATP binding;GO:0009384//N-acylmannosamine kinase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0008761//UDP-N-acetylglucosamine 2-epimerase activity;GO:0046872//metal ion binding",K12409//Metabolic pathways;Amino sugar and nucleotide sugar metabolism
10021,21,0,0,0,0,13,0,26,20,0,6,0,HCN4;hyperpolarization activated cyclic nucleotide-gated potassium channel 4,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043195//terminal bouton;GO:0031226//intrinsic component of plasma membrane,GO:0008015//blood circulation;GO:0001701//in utero embryonic development;GO:0034765//regulation of ion transmembrane transport;GO:0071321//cellular response to cGMP;GO:0035725//sodium ion transmembrane transport;GO:0002027//regulation of heart rate;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0006936//muscle contraction;GO:0006812//cation transport;GO:0071320//cellular response to cAMP,GO:0042802//identical protein binding;GO:0030552//cAMP binding;GO:0005248//voltage-gated sodium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005261//cation channel activity;GO:0005222//intracellular cAMP activated cation channel activity,-
10022,0,0,0,0,0,0,0,0,21,0,0,0,INSL5;insulin-like 5,GO:0005576//extracellular region,-,GO:0005179//hormone activity,-
10023,0,0,0,0,9,0,0,0,19,0,0,683,FRAT1;frequently rearranged in advanced T-cell lymphomas 1,GO:0005737//cytoplasm,GO:0016055//Wnt signaling pathway;GO:0000578//embryonic axis specification,-,K03069//Wnt signaling pathway
100233156,8,0,0,0,8,0,0,0,12,0,3,0,LOC100233156;tektin 4 pseudogene,-,-,-,K04688//TGF-beta signaling pathway;Fc gamma R-mediated phagocytosis;ErbB signaling pathway;Insulin signaling pathway;Acute myeloid leukemia;mTOR signaling pathway
10024,0,0,0,0,0,37,0,20,39,0,0,248,TROAP;trophinin associated protein,GO:0005737//cytoplasm,GO:0007155//cell adhesion,GO:0005515//protein binding,-
10025,47,1,0,8,13,0,34,135,53,0,51,0,MED16;mediator complex subunit 16,GO:0016020//membrane;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:2000273//positive regulation of receptor activity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0030375//thyroid hormone receptor coactivator activity;GO:0004872//receptor activity;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0003824//catalytic activity;GO:0042809//vitamin D receptor binding,-
10026,0,0,0,5,0,0,0,0,2,0,17,27,"PIGK;phosphatidylinositol glycan anchor biosynthesis, class K",GO:0016020//membrane;GO:0042765//GPI-anchor transamidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0006501//C-terminal protein lipidation;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006457//protein folding;GO:0016255//attachment of GPI anchor to protein,GO:0003756//protein disulfide isomerase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0003923//GPI-anchor transamidase activity;GO:0034235//GPI anchor binding,K05290//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
100271702,0,0,0,0,0,0,0,0,23,94,0,0,LINC00940;long intergenic non-protein coding RNA 940,-,-,-,-
100271715,0,46,0,7,0,8,15,83,76,1,10,0,ARHGEF33;Rho guanine nucleotide exchange factor (GEF) 33,-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K08878//Pathways in cancer;Chronic myeloid leukemia
100271836,31,0,0,0,2,0,16,81,25,5,0,335,SMG1P3;SMG1 pseudogene 3,-,-,-,K08873//mRNA surveillance pathway
100271846,69,0,0,0,0,0,0,1,0,1,0,0,"ERVV-2;endogenous retrovirus group V, member 2",GO:0016021//integral component of membrane,-,-,K04257//Olfactory transduction;K13962//Gastric acid secretion
100271849,0,0,0,0,0,0,0,0,0,0,1,0,MEF2B;myocyte enhancer factor 2B,GO:0030054//cell junction;GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042826//histone deacetylase binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
100271873,14,0,0,0,0,10,0,0,13,0,0,0,AIRN;antisense of IGF2R non-protein coding RNA,-,-,-,-
100271874,0,0,49,0,0,0,33,92,2,0,17,0,ZNRF2P2;zinc and ring finger 2 pseudogene 2,-,-,-,-
100271927,21,0,1,0,11,2,1,5,0,0,3,0,RASA4B;RAS p21 protein activator 4B,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity;GO:0046872//metal ion binding,K12380//MAPK signaling pathway - fly
100272147,0,0,0,0,19,0,0,0,0,0,0,0,CMC4;C-x(9)-C motif containing 4,GO:0005739//mitochondrion,GO:0008283//cell proliferation,-,-
100272216,0,0,45,0,0,15,0,1,0,33,20,106,LOC100272216;uncharacterized LOC100272216,-,-,-,K14316//RNA transport
100286844,0,166,0,51,99,0,0,45,12,0,185,0,BCDIN3D-AS1;BCDIN3D antisense RNA 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Arginine and proline metabolism;Biotin metabolism
100286922,0,0,0,0,0,0,0,0,18,0,0,0,"LOC100286922;DnaJ (Hsp40) homolog, subfamily B, member 3 pseudogene",-,-,-,-
100286979,2,0,0,0,0,16,0,0,1,98,2,0,ANAPC1P1;anaphase promoting complex subunit 1 pseudogene 1,-,-,-,K03348//Cell cycle;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis;Meiosis - yeast;HTLV-I infection;Oocyte meiosis
100287042,0,41,48,18,0,0,0,157,0,176,39,0,LOC100287042;uncharacterized LOC100287042,-,-,-,-
100287072,0,0,0,0,0,41,20,0,13,0,26,0,"LOC100287072;ribosomal protein S6 kinase, 70kDa, polypeptide 1 pseudogene",-,-,-,K04688//Acute myeloid leukemia;mTOR signaling pathway;Insulin signaling pathway;TGF-beta signaling pathway;Fc gamma R-mediated phagocytosis;ErbB signaling pathway
100287098,0,0,0,0,0,0,0,92,0,1,41,0,LOC100287098;uncharacterized LOC100287098,-,-,-,-
100287102,0,0,0,0,0,0,0,0,4,36,0,0,DDX11L1;DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 1,-,-,-,-
100287114,0,0,0,0,0,0,0,0,2,0,0,0,LINC00421;long intergenic non-protein coding RNA 421,-,-,-,-
100287171,2,0,0,0,0,10,0,1,12,0,13,3,WASH1;WAS protein family homolog 1,GO:0031901//early endosome membrane;GO:0071203//WASH complex;GO:0055038//recycling endosome membrane;GO:0005769//early endosome;GO:0055037//recycling endosome,"GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0042147//retrograde transport, endosome to Golgi;GO:0016197//endosomal transport",GO:0003779//actin binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,-
100287216,0,1,0,0,8,0,83,143,104,0,0,0,SH3RF3-AS1;SH3RF3 antisense RNA 1,-,-,-,-
100287226,7,0,0,0,0,0,0,0,3,0,0,0,ZNF729;zinc finger protein 729,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100287284,0,0,0,0,0,11,0,0,0,0,0,0,MANSC4;MANSC domain containing 4,GO:0016021//integral component of membrane,-,-,-
100287327,0,0,0,0,0,0,2,0,15,0,0,0,USP17L17;ubiquitin specific peptidase 17-like family member 17,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
100287362,0,0,0,0,0,0,0,58,0,0,0,0,"PRSS46;protease, serine, 46",-,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
100287482,0,0,0,0,0,0,40,0,0,0,0,0,SMKR1;small lysine-rich protein 1,-,-,-,-
100287569,17,0,0,0,0,0,0,0,0,0,0,0,LINC00173;long intergenic non-protein coding RNA 173,-,-,-,-
100287596,0,0,5,0,0,0,4,75,14,0,0,0,DDX11L5;DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 5,-,-,-,-
100287718,0,0,0,0,0,25,0,0,41,0,0,0,ANKRD66;ankyrin repeat domain 66,-,-,-,K01395//Protein digestion and absorption
100287722,0,0,0,0,0,0,0,0,39,0,0,0,AP4B1-AS1;AP4B1 antisense RNA 1,-,-,-,K12401//Lysosome
100287898,0,0,0,0,0,0,0,0,26,0,0,0,TTC34;tetratricopeptide repeat domain 34,-,-,-,-
100287932,0,0,0,5,21,0,18,0,0,0,0,0,TIMM23;translocase of inner mitochondrial membrane 23 homolog (yeast),GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005744//mitochondrial inner membrane presequence translocase complex,GO:0071806//protein transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion,GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity;GO:0005515//protein binding,-
100288123,0,0,17,0,0,0,0,14,0,0,0,0,LOC100288123;uncharacterized LOC100288123,-,-,-,-
100288142,0,0,0,0,1,0,0,0,1,0,0,0,"NBPF20;neuroblastoma breakpoint family, member 20",GO:0005737//cytoplasm,-,-,-
100288162,0,154,35,108,128,0,1,774,80,0,801,194,LOC100288162;uncharacterized LOC100288162,-,-,-,-
100288332,0,0,0,0,1,0,0,0,1,0,0,0,"NPIPA5;nuclear pore complex interacting protein family, member A5",-,-,-,-
100288346,77,0,0,0,0,0,0,36,6,0,0,0,NCAM1-AS1;NCAM1 antisense RNA1,-,-,-,K06491//Cell adhesion molecules (CAMs);Prion diseases
100288413,0,0,0,0,0,0,0,0,61,0,0,0,"ERVMER34-1;endogenous retrovirus group MER34, member 1",GO:0016021//integral component of membrane;GO:0019031//viral envelope,-,-,-
100288485,0,0,0,0,0,17,14,0,0,0,0,0,MTRNR2L7;MT-RNR2-like 7,GO:0005737//cytoplasm;GO:0005576//extracellular region,-,-,-
100288486,0,0,0,0,0,20,1,0,11,4,0,0,DDX11L9;DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 9,-,-,-,-
100288520,0,0,0,0,0,0,0,0,1,0,0,0,USP17L15;ubiquitin specific peptidase 17-like family member 15,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
100288524,0,0,0,0,0,11,0,0,2,1,0,0,WI2-2373I1.2;forkhead box L1-like,-,-,-,-
100288527,11,0,1,0,3,31,89,100,83,288,27,30,"REXO1L2P;REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 2 (pseudogene)",-,-,-,K14570//Ribosome biogenesis in eukaryotes
100288615,0,0,0,0,0,0,2,0,0,0,0,0,"WHAMMP1;WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 1",-,-,-,-
100288637,0,0,0,0,0,0,0,34,32,0,13,0,LOC100288637;OTU deubiquitinase 7A pseudogene,-,-,-,-
100288730,0,74,90,84,105,0,12,7,95,0,73,0,PAN3-AS1;PAN3 antisense RNA 1,-,-,-,K12572//RNA degradation
100288797,0,26,0,0,0,0,0,0,1,0,0,0,TMEM239;transmembrane protein 239,GO:0016021//integral component of membrane,-,-,-
100288805,0,0,0,0,0,0,80,24,76,0,16,0,"HYDIN2;HYDIN2, axonemal central pair apparatus protein (pseudogene)",-,-,-,-
100288866,0,0,0,0,0,0,0,0,17,0,0,0,LOC100288866;uncharacterized LOC100288866,-,-,-,K02583//Transcriptional misregulation in cancer;Neurotrophin signaling pathway;Cytokine-cytokine receptor interaction
100288966,1,0,0,0,0,0,0,0,1,140,0,0,LOC100288966;POTE ankyrin domain family member D-like,-,-,-,-
100288974,0,0,0,0,0,0,0,0,1,0,0,0,"LOC100288974;BMS1 homolog, ribosome assembly protein (yeast) pseudogene",-,-,-,K14569//Ribosome biogenesis in eukaryotes
100289017,0,0,0,0,0,1,0,0,11,0,0,0,"MOXD2P;monooxygenase, DBH-like 2, pseudogene",-,GO:0055114//oxidation-reduction process,"GO:0005507//copper ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen",K00503//Tyrosine metabolism;Metabolic pathways
100289019,0,0,0,0,5,0,17,39,0,0,0,0,LOC100289019;uncharacterized LOC100289019,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
100289137,0,0,0,0,0,0,0,0,22,0,0,0,"FAM95C;family with sequence similarity 95, member C",-,-,-,K00490//Arachidonic acid metabolism;Metabolic pathways
100289187,0,0,0,0,0,16,36,0,3,0,0,235,GS1-259H13.2;transmembrane protein 225-like,-,-,-,-
100289341,0,0,0,0,8,0,0,0,43,0,0,0,MAN1B1-AS1;MAN1B1 antisense RNA 1 (head to head),-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
100289388,0,0,1,45,61,0,0,113,6,0,38,0,KCTD21-AS1;KCTD21 antisense RNA 1,-,-,-,K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
100289410,0,0,0,0,10,0,0,79,10,0,35,0,MCF2L-AS1;MCF2L antisense RNA 1,-,-,-,-
100289495,0,0,0,10,0,17,0,0,0,230,0,0,LOC100289495;uncharacterized LOC100289495,-,-,-,K04514//TGF-beta signaling pathway;Shigellosis;Leukocyte transendothelial migration;Salmonella infection;Axon guidance;Chemokine signaling pathway;Focal adhesion;Pathogenic Escherichia coli infection;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Wnt signaling pathway;K00889//Phosphatidylinositol signaling system;Metabolic pathways;Regulation of actin cytoskeleton;Endocytosis;Fc gamma R-mediated phagocytosis;Focal adhesion;Inositol phosphate metabolism
100289574,120,0,0,0,0,23,43,11,60,0,6,0,HERC2P4;hect domain and RLD 2 pseudogene 4,-,-,-,K10595//Ubiquitin mediated proteolysis
100289580,0,0,0,5,19,12,33,322,6,189,35,0,LOC100289580;uncharacterized LOC100289580,-,-,-,-
100289635,0,0,0,0,21,15,1,0,41,0,0,0,ZNF605;zinc finger protein 605,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100289656,0,0,0,0,2,0,0,0,0,0,0,0,LOC100289656;Dexi homolog (mouse) pseudogene,-,-,-,-
100289673,0,0,0,0,0,0,1,0,25,0,0,0,LOC100289673;phosphoglycerate mutase family member 5 pseudogene,-,-,-,-
100289678,0,0,0,0,0,21,0,0,14,0,0,0,ZNF783;zinc finger family member 783,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
100293516,40,1,1,6,25,0,0,0,31,0,5,0,ZNF587B;zinc finger protein 587B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
100294145,0,0,0,0,0,0,0,0,10,0,0,0,LOC100294145;uncharacterized LOC100294145,-,-,-,-
100294362,0,483,87,184,302,0,0,400,282,141,467,0,LOC100294362;uncharacterized LOC100294362,-,-,-,K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
1003,0,0,0,0,0,0,81,28,27,0,7,0,"CDH5;cadherin 5, type 2 (vascular endothelium)",GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0005923//tight junction;GO:0005886//plasma membrane,GO:0034332//adherens junction organization;GO:0045216//cell-cell junction organization;GO:0001955//blood vessel maturation;GO:2000114//regulation of establishment of cell polarity;GO:0034329//cell junction assembly;GO:0008285//negative regulation of cell proliferation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0019903//protein phosphatase binding;GO:0008013//beta-catenin binding;GO:0005102//receptor binding,K06533//Cell adhesion molecules (CAMs);Leukocyte transendothelial migration
100302129,0,0,0,0,0,16,0,0,0,0,0,0,MIR1915;microRNA 1915,-,-,-,-
100302141,0,0,0,0,0,0,25,0,0,0,0,0,MIR1913;microRNA 1913,-,-,-,-
100302144,0,0,0,0,0,0,0,0,22,0,0,0,MIR1912;microRNA 1912,-,-,-,-
100302149,0,0,0,0,0,0,0,0,9,0,0,0,MIR1249;microRNA 1249,-,-,-,-
100302150,0,0,0,0,0,19,0,0,0,0,0,0,MIR1296;microRNA 1296,-,-,-,-
100302153,0,0,0,0,0,0,0,0,3,0,0,0,MIR1298;microRNA 1298,-,-,-,-
100302155,0,0,0,0,0,0,0,0,23,0,0,0,MIR1256;microRNA 1256,-,-,-,-
100302159,0,0,0,0,0,0,0,0,17,0,0,0,MIR548F3;microRNA 548f-3,-,-,-,-
100302163,0,0,0,0,0,0,30,0,0,0,0,0,MIR1278;microRNA 1278,-,-,-,-
100302165,0,0,0,0,0,0,0,0,9,0,0,0,MIR1273A;microRNA 1273a,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
100302166,0,0,0,0,0,8,0,0,0,0,0,0,MIR1322;microRNA 1322,-,-,-,-
100302167,0,0,0,0,0,0,23,0,33,0,0,0,MIR1299;microRNA 1299,-,-,-,-
100302171,0,0,0,0,0,0,0,0,9,0,0,0,MIR1321;microRNA 1321,-,-,-,-
100302177,0,0,0,0,0,0,0,0,0,37,0,0,MIR1269A;microRNA 1269a,-,-,-,-
100302182,0,0,0,7,16,0,0,0,0,0,0,0,MIR1279;microRNA 1279,-,-,-,-
100302184,0,0,0,0,0,0,0,0,17,0,0,0,MIR1272;microRNA 1272,-,-,-,-
100302191,0,0,0,0,0,15,0,0,15,0,0,0,MIR548I4;microRNA 548i-4,-,-,-,-
100302192,0,0,0,0,0,0,0,0,3,184,0,0,MIR548F1;microRNA 548f-1,-,-,-,-
100302193,0,0,0,0,0,0,0,0,2,0,0,0,MIR1255A;microRNA 1255a,-,-,-,-
100302209,0,0,0,0,0,0,2,0,0,0,0,0,MIR1185-2;microRNA 1185-2,-,-,-,-
100302211,39,0,0,0,0,0,0,0,0,0,0,0,MIR1203;microRNA 1203,-,-,-,-
100302223,0,0,41,0,0,0,0,0,0,0,0,0,MIR1302-8;microRNA 1302-8,-,-,-,-
100302233,0,0,0,0,0,0,0,0,15,0,0,0,MIR1268A;microRNA 1268a,-,-,-,-
100302235,0,0,0,0,0,0,0,0,5,0,0,0,MIR1179;microRNA 1179,-,-,-,-
100302246,0,0,0,0,0,0,13,0,13,0,0,0,MIR1301;microRNA 1301,-,-,-,-
100302254,162,21233,7861,12963,24049,1,916,11111,4301,816,20645,933,MIR1282;microRNA 1282,-,-,-,-
100302255,0,0,0,0,0,0,47,0,0,0,0,0,MIR1323;microRNA 1323,-,-,-,-
100302261,0,0,0,0,0,0,0,0,36,0,0,0,MIR1910;microRNA 1910,-,-,-,-
100302270,0,0,0,0,0,5,0,0,0,0,0,0,MIR1305;microRNA 1305,-,-,-,-
100302275,0,0,0,0,0,0,0,0,0,0,16,0,MIR548L;microRNA 548l,-,-,-,-
100302276,0,0,0,0,0,0,1,0,23,0,0,0,MIR1290;microRNA 1290,-,-,-,-
100302277,0,0,0,0,0,0,0,0,10,0,0,0,MIR548I2;microRNA 548i-2,-,-,-,-
100302281,0,0,0,0,0,0,0,0,17,0,0,0,MIR1208;microRNA 1208,-,-,-,-
100302287,0,0,0,0,0,0,10,0,31,0,9,0,MIR548H3;microRNA 548h-3,-,-,-,-
100303728,173,284,163,155,392,0,6,610,29,6,1747,0,SLC25A5-AS1;SLC25A5 antisense RNA 1,-,-,-,K05863//Calcium signaling pathway;Influenza A;Huntington's disease;HTLV-I infection;Parkinson's disease
100303755,0,0,0,0,0,0,0,0,31,85,7,0,PET117;PET117 homolog (S. cerevisiae),GO:0005739//mitochondrion,-,-,-
100306975,0,0,0,0,0,9,0,0,26,0,0,0,"NDUFAF4P1;NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 pseudogene 1",-,-,-,-
100310846,0,0,0,0,0,0,0,0,21,5,1,0,ANKRD61;ankyrin repeat domain 61,-,-,-,-
100313769,0,0,0,0,0,27,0,0,0,0,0,0,MIR320B2;microRNA 320b-2,-,-,-,-
100313773,0,0,0,0,0,9,0,0,0,0,0,0,MIR548H2;microRNA 548h-2,-,-,-,-
100313774,0,0,0,0,0,0,0,0,25,0,0,0,MIR302E;microRNA 302e,-,-,-,-
100313835,0,0,0,0,0,14,0,0,0,0,0,0,MIR1255B2;microRNA 1255b-2,-,-,-,-
100313837,45,169,133,14,219,0,0,1169,202,2,219,1,MIR762;microRNA 762,-,-,-,-
100313839,0,0,0,0,0,0,25,0,34,0,0,0,MIR2114;microRNA 2114,-,-,-,-
100313841,0,121,107,174,267,0,0,137,29,0,211,0,MIR548Q;microRNA 548q,-,-,-,-
100313842,0,0,0,0,0,17,0,0,0,0,23,0,MIR2276;microRNA 2276,-,-,-,-
100313884,0,0,0,0,0,0,28,0,5,0,0,0,MIR548H4;microRNA 548h-4,-,-,-,-
100316904,0,0,0,0,0,0,0,0,12,0,0,0,"SAP25;Sin3A-associated protein, 25kDa",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
100329135,0,0,0,0,0,30,0,0,8,0,0,0,TRPC5OS;TRPC5 opposite strand,-,-,-,-
100335030,73,0,0,0,0,0,0,0,8,0,1,0,LOC100335030;FGFR1 oncogene partner 2 pseudogene,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K12656//RIG-I-like receptor signaling pathway
100337591,0,0,0,0,0,0,0,0,0,0,4,0,"SNORA70F;small nucleolar RNA, H/ACA box 70F",-,-,-,-
10036,0,1,0,1,3,0,44,0,20,0,20,0,"CHAF1A;chromatin assembly factor 1, subunit A (p150)",GO:0033186//CAF-1 complex;GO:0043234//protein complex;GO:0000790//nuclear chromatin,"GO:0006260//DNA replication;GO:0006351//transcription, DNA-templated;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0031497//chromatin assembly;GO:0007049//cell cycle;GO:0006461//protein complex assembly;GO:0006335//DNA replication-dependent nucleosome assembly",GO:0070087//chromo shadow domain binding;GO:0003682//chromatin binding;GO:0051082//unfolded protein binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
100379220,0,0,0,0,12,0,0,0,0,0,0,0,"TMED11P;transmembrane emp24 protein transport domain containing 11, pseudogene",-,-,-,-
100379571,0,22,56,17,0,0,0,39,0,3,186,0,BACE1-AS;BACE1 antisense RNA,-,-,-,K00797//beta-Alanine metabolism;Metabolic pathways;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K11447//Transcriptional misregulation in cancer;K14443//RNA degradation;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
10038,82,18,0,0,16,0,0,0,9,0,0,0,PARP2;poly (ADP-ribose) polymerase 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0006284//base-excision repair;GO:0006471//protein ADP-ribosylation;GO:0006281//DNA repair;GO:0097191//extrinsic apoptotic signaling pathway,GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity,K10798//NF-kappa B signaling pathway;Base excision repair
100381270,0,0,1,39,62,0,0,0,20,0,0,0,"ZBED6;zinc finger, BED-type containing 6",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10039,0,0,0,0,0,11,26,0,0,3,26,0,"PARP3;poly (ADP-ribose) polymerase family, member 3",GO:0005634//nucleus;GO:0035861//site of double-strand break;GO:0005814//centriole,GO:0060236//regulation of mitotic spindle organization;GO:0000723//telomere maintenance;GO:0006302//double-strand break repair;GO:1990166//protein localization to site of double-strand break;GO:0051106//positive regulation of DNA ligation;GO:0006281//DNA repair;GO:0006471//protein ADP-ribosylation,GO:0003824//catalytic activity;GO:0003950//NAD+ ADP-ribosyltransferase activity,K10798//Base excision repair;NF-kappa B signaling pathway
1004,90,0,10,0,0,25,15,0,1,0,10,0,"CDH6;cadherin 6, type 2, K-cadherin (fetal kidney)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization,GO:0005509//calcium ion binding,-
10040,0,46,61,62,205,0,17,0,2,5,25,0,TOM1L1;target of myb1 (chicken)-like 1,GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005795//Golgi stack;GO:0005768//endosome;GO:0005764//lysosome;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0045839//negative regulation of mitosis;GO:0032147//activation of protein kinase activity;GO:0006886//intracellular protein transport;GO:0031954//positive regulation of protein autophosphorylation;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:2000278//regulation of DNA biosynthetic process,GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0043130//ubiquitin binding;GO:0030276//clathrin binding;GO:0030295//protein kinase activator activity,K12404//Lysosome
100419743,0,0,0,0,0,1,0,0,5,0,0,0,DBET;D4Z4 binding element transcript (non-protein coding),-,-,-,-
10042,0,0,1,0,44,0,0,0,13,1,0,0,HMGXB4;HMG box domain containing 4,GO:0016589//NURF complex,GO:0008333//endosome to lysosome transport;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway,GO:0003677//DNA binding,-
100420587,0,0,0,0,0,0,0,0,0,0,9,84,LOC100420587;SHC SH2-domain binding protein 1 pseudogene,-,-,-,-
100421577,0,0,0,0,0,0,3,0,33,0,0,0,"FAM21EP;family with sequence similarity 21, member A pseudogene",-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
100422556,0,0,0,0,0,0,0,0,0,0,4,0,"LOC100422556;Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) pseudogene",-,-,-,-
100422826,0,0,0,0,0,0,0,0,0,0,5,0,MIR4274;microRNA 4274,-,-,-,-
100422828,0,0,0,0,0,0,0,0,2,0,0,0,MIR4287;microRNA 4287,-,-,-,-
100422847,0,0,0,0,0,0,0,0,15,0,0,0,MIR514B;microRNA 514b,-,-,-,-
100422849,0,0,0,0,0,0,0,0,24,0,0,0,MIR548T;microRNA 548t,-,-,-,-
100422850,0,0,0,0,0,0,3,0,0,0,0,0,MIR548V;microRNA 548v,-,-,-,-
100422854,105,0,0,0,0,2,0,0,14,0,0,0,MIR3187;microRNA 3187,-,-,-,-
100422855,0,0,0,0,0,0,0,0,5,0,0,0,MIR4301;microRNA 4301,-,-,-,-
100422857,0,0,0,0,0,0,19,0,13,0,0,0,MIR4318;microRNA 4318,-,-,-,-
100422858,29,0,0,0,0,0,0,0,0,0,0,0,MIR4285;microRNA 4285,-,-,-,-
100422865,0,0,0,0,0,0,0,0,12,0,0,0,MIR4320;microRNA 4320,-,-,-,-
100422868,0,0,0,0,0,0,0,0,5,0,0,0,MIR4270;microRNA 4270,-,-,-,-
100422869,0,0,0,0,0,8,0,0,0,0,0,0,MIR3152;microRNA 3152,-,-,-,-
100422871,0,0,0,0,0,1,0,0,0,0,0,0,MIR3117;microRNA 3117,-,-,-,-
100422873,0,0,0,0,0,0,0,0,1,0,0,0,MIR4297;microRNA 4297,-,-,-,-
100422874,0,0,0,0,0,0,0,0,10,0,0,237,MIR4279;microRNA 4279,-,-,-,-
100422877,0,0,0,0,0,0,5,0,0,0,0,0,MIR3202-2;microRNA 3202-2,-,-,-,-
100422879,0,0,0,18,29,0,0,0,0,0,8,0,MIR3124;microRNA 3124,-,-,-,-
100422896,0,0,0,0,0,0,0,0,4,0,0,0,MIR3140;microRNA 3140,-,-,-,-
100422899,0,0,0,0,0,0,0,0,11,0,0,0,MIR3190;microRNA 3190,-,-,-,-
100422903,0,0,0,0,0,5,0,0,0,0,0,0,MIR4288;microRNA 4288,-,-,-,-
100422911,0,0,0,0,0,23,0,0,0,0,0,0,MIR500B;microRNA 500b,-,-,-,-
100422918,0,0,0,0,0,0,0,0,7,0,0,0,MIR3167;microRNA 3167,-,-,-,-
100422924,0,0,0,0,0,0,0,0,12,0,0,0,MIR4303;microRNA 4303,-,-,-,-
100422926,0,0,0,0,0,0,17,0,0,0,0,0,MIR3137;microRNA 3137,-,-,-,-
100422928,91,0,0,0,0,0,0,0,0,0,0,0,MIR3127;microRNA 3127,-,-,-,-
100422933,0,0,0,0,0,0,0,28,0,0,0,0,MIR378B;microRNA 378b,-,-,-,-
100422942,0,0,0,0,0,0,0,0,22,0,0,0,MIR3133;microRNA 3133,-,-,-,-
100422944,0,0,0,0,0,0,0,0,12,0,3,0,MIR3186;microRNA 3186,-,-,-,-
100422946,0,0,0,0,0,0,0,0,15,0,0,0,MIR3116-2;microRNA 3116-2,-,-,-,-
100422948,0,0,0,0,0,4,0,0,0,0,0,0,MIR4284;microRNA 4284,-,-,-,-
100422952,0,0,0,0,13,0,0,0,0,0,19,0,MIR4271;microRNA 4271,-,-,-,-
100422953,0,0,0,0,0,0,0,0,12,0,0,0,MIR3165;microRNA 3165,-,-,-,-
100422955,0,0,0,24,55,0,0,0,0,0,25,0,MIR4273;microRNA 4273,-,-,-,-
100422957,0,0,0,0,0,0,0,1,0,0,0,0,MIR3131;microRNA 3131,-,-,-,-
100422964,0,0,0,0,0,0,0,0,11,0,0,0,MIR3150A;microRNA 3150a,-,-,-,-
100422966,0,0,0,0,0,0,0,0,0,0,9,0,MIR4277;microRNA 4277,-,-,-,-
100422969,0,0,0,0,0,0,0,0,6,0,0,0,MIR2909;microRNA 2909,-,-,-,-
100422978,0,403,123,242,280,0,0,0,0,0,147,0,MIR3185;microRNA 3185,-,-,-,-
100422980,65,0,0,0,0,0,0,0,0,0,0,0,MIR4323;microRNA 4323,-,-,-,-
100422986,0,0,0,0,36,0,0,0,0,0,0,0,MIR3125;microRNA 3125,-,-,-,-
100422991,0,0,0,18,60,5,51,0,9,0,24,0,MIR1260B;microRNA 1260b,-,-,-,-
100422992,0,0,0,0,0,0,0,0,1,0,0,0,MIR3151;microRNA 3151,-,-,-,-
100422994,0,0,0,0,0,0,0,0,21,0,0,0,MIR4267;microRNA 4267,-,-,-,-
100423009,0,0,0,0,0,0,0,0,0,0,3,0,MIR4329;microRNA 4329,-,-,-,-
100423015,0,0,0,0,0,0,0,0,30,0,0,0,MIR4289;microRNA 4289,-,-,-,-
100423028,0,0,0,0,0,0,0,0,16,0,0,0,MIR4254;microRNA 4254,-,-,-,-
100423033,129,0,0,0,0,0,0,0,3,0,0,0,MIR3158-2;microRNA 3158-2,-,-,-,-
100423036,0,0,0,0,0,0,0,0,22,0,7,0,MIR2355;microRNA 2355,-,-,-,-
100423039,0,0,0,0,0,0,22,0,0,0,0,0,MIR3132;microRNA 3132,-,-,-,-
100423040,10,0,0,0,0,0,0,0,1,0,0,0,MIR3166;microRNA 3166,-,-,-,-
100423041,0,0,0,0,0,0,0,0,1,0,0,0,MIR4296;microRNA 4296,-,-,-,-
100423062,0,0,0,0,0,0,48,0,24,0,16,0,IGLL5;immunoglobulin lambda-like polypeptide 5,GO:0070062//extracellular vesicular exosome,-,-,K06554//Primary immunodeficiency
10043,0,0,0,0,0,8,5,58,21,0,0,0,TOM1;target of myb1 (chicken),GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005768//endosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006897//endocytosis;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0006886//intracellular protein transport,GO:0030276//clathrin binding;GO:0005515//protein binding,K04705//Endocytosis;Jak-STAT signaling pathway;K12404//Lysosome
100431172,50,0,0,0,0,0,0,0,11,0,0,0,"KLRF2;killer cell lectin-like receptor subfamily F, member 2",GO:0005887//integral component of plasma membrane,GO:0050663//cytokine secretion;GO:0043320//natural killer cell degranulation,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0030246//carbohydrate binding,-
10044,178,0,0,0,0,7,5,63,14,0,0,0,SH2D3C;SH2 domain containing 3C,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0009967//positive regulation of signal transduction;GO:0007254//JNK cascade;GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K08889//Adherens junction
10045,0,0,0,0,0,0,14,66,38,0,22,0,SH2D3A;SH2 domain containing 3A,-,GO:0009967//positive regulation of signal transduction;GO:0007254//JNK cascade;GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K07527//Axon guidance
10046,0,0,0,0,0,0,44,0,18,0,14,300,MAMLD1;mastermind-like domain containing 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008584//male gonad development",-,K06061//Notch signaling pathway
100462977,0,0,0,0,0,10,18,0,13,0,0,0,MTRNR2L1;MT-RNR2-like 1,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
100462981,19,0,0,0,0,0,0,0,0,0,0,0,MTRNR2L2;MT-RNR2-like 2,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
100462983,0,0,0,0,0,0,0,0,25,0,0,0,MTRNR2L3;MT-RNR2-like 3,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
100463285,0,0,0,0,0,0,0,0,1,0,0,0,MTRNR2L4;MT-RNR2-like 4,GO:0005737//cytoplasm;GO:0005576//extracellular region,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K11447//Transcriptional misregulation in cancer
100463289,0,0,0,0,0,10,0,0,1,0,0,0,MTRNR2L5;MT-RNR2-like 5,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways;K01539//Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
100463482,0,0,0,0,0,0,0,0,12,0,0,0,MTRNR2L6;MT-RNR2-like 6,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
100463486,0,0,0,0,27,0,0,0,17,0,0,0,MTRNR2L8;MT-RNR2-like 8,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
100463487,0,0,0,0,0,0,0,0,1,0,0,0,MTRNR2L9;MT-RNR2-like 9 (pseudogene),GO:0005737//cytoplasm;GO:0005576//extracellular region,-,-,-
100463488,0,0,0,0,0,5,0,0,14,0,0,0,MTRNR2L10;MT-RNR2-like 10,GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
10047,0,0,0,0,0,0,0,42,0,0,0,0,CST8;cystatin 8 (cystatin-related epididymal specific),GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,-
10048,0,1,101,74,118,11,31,0,8,0,0,0,RANBP9;RAN binding protein 9,GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0005634//nucleus,GO:0007020//microtubule nucleation;GO:0006461//protein complex assembly;GO:0007411//axon guidance,GO:0019899//enzyme binding;GO:0008536//Ran GTPase binding;GO:0005515//protein binding,-
10049,0,0,0,9,69,0,0,0,13,0,0,0,"DNAJB6;DnaJ (Hsp40) homolog, subfamily B, member 6",GO:0005829//cytosol;GO:0016020//membrane;GO:0005730//nucleolus;GO:0030018//Z disc;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045109//intermediate filament organization;GO:0090084//negative regulation of inclusion body assembly;GO:0032781//positive regulation of ATPase activity;GO:0006457//protein folding;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005515//protein binding;GO:0001671//ATPase activator activity;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding;GO:0051087//chaperone binding,-
100499466,201,0,0,0,18,0,23,0,36,0,5,0,LINC00674;long intergenic non-protein coding RNA 674,-,-,-,K11247//Endocytosis
100499483,0,0,0,0,0,0,0,0,0,0,5,0,CCDC180;coiled-coil domain containing 180,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
100499484,24,0,0,0,0,0,29,0,0,0,0,0,LOC100499484;SUGT1-1300002K09Rik pseudogene,-,-,-,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction
1005,103,0,0,0,0,10,26,0,40,0,9,1,"CDH7;cadherin 7, type 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0034332//adherens junction organization;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization,GO:0005509//calcium ion binding,-
10050,0,0,0,0,0,11,34,0,22,0,10,0,"SLC17A4;solute carrier family 17, member 4",GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016020//membrane,GO:0035725//sodium ion transmembrane transport;GO:0006796//phosphate-containing compound metabolic process;GO:0035435//phosphate ion transmembrane transport;GO:0006814//sodium ion transport,GO:0005436//sodium:phosphate symporter activity,-
100500804,0,4,0,1,0,0,0,0,0,0,0,0,MIR3654;microRNA 3654,-,-,-,-
100500813,0,0,0,0,0,13,0,0,9,0,0,0,MIR3646;microRNA 3646,-,-,-,-
100500815,135,0,0,0,0,95,61,117,132,194,5,706,MIR3687-1;microRNA 3687-1,-,-,-,-
100500824,0,65,138,137,112,0,0,85,0,0,197,0,MIR3650;microRNA 3650,-,-,-,-
100500829,4,0,0,0,0,0,0,0,0,0,0,0,MIR3943;microRNA 3943,-,-,-,-
100500841,0,0,0,0,0,0,0,0,25,0,0,0,MIR3678;microRNA 3678,-,-,-,-
100500845,0,0,0,0,0,0,0,0,2,0,0,0,MIR642B;microRNA 642b,-,-,-,-
100500850,0,0,0,0,0,22,0,0,0,0,0,0,MIR3682;microRNA 3682,-,-,-,-
100500851,0,0,37,56,79,0,0,0,10,0,185,0,MIR3918;microRNA 3918,-,-,-,-
100500856,39,0,0,0,0,0,0,0,0,0,0,0,MIR548Z;microRNA 548z,-,-,-,-
100500859,0,0,0,0,0,0,0,0,10,0,0,0,MIR3921;microRNA 3921,-,-,-,-
100500861,0,2,0,11,14,0,0,98,0,0,35,0,MIR3665;microRNA 3665,-,-,-,-
100500862,2,0,0,0,0,42,90,71,24,9,4,298,MIR3648-1;microRNA 3648-1,-,-,-,-
100500866,0,0,0,0,0,0,17,0,0,0,0,0,MIR3941;microRNA 3941,-,-,-,-
100500871,0,0,0,0,0,7,0,0,13,0,0,0,MIR3622B;microRNA 3622b,-,-,-,-
100500872,0,0,0,20,17,0,0,0,0,0,27,0,MIR3911;microRNA 3911,-,-,-,-
100500876,0,0,0,0,0,1,0,0,18,0,0,0,MIR3675;microRNA 3675,-,-,-,-
100500878,0,0,0,0,0,0,0,0,9,0,0,0,MIR3679;microRNA 3679,-,-,-,-
100500894,0,0,0,0,0,1,0,0,0,0,0,0,MIR3690;microRNA 3690,-,-,-,-
100500895,0,0,0,0,0,0,0,0,15,0,0,0,MIR548AA2;microRNA 548aa-2,-,-,-,-
100500896,0,0,0,0,0,0,18,0,10,0,0,0,MIR3666;microRNA 3666,-,-,-,-
100500900,0,0,0,0,0,0,12,0,0,0,0,0,MIR3691;microRNA 3691,-,-,-,-
100500905,0,378,81,466,787,0,0,56,37,0,768,1,MIR3661;microRNA 3661,-,-,-,K03094//Circadian rhythm - mammal;TGF-beta signaling pathway;Ubiquitin mediated proteolysis;Cell cycle;Cell cycle - yeast;Herpes simplex infection;Protein processing in endoplasmic reticulum;Oocyte meiosis;Wnt signaling pathway;K04382//Oocyte meiosis;Wnt signaling pathway;Hepatitis C;mRNA surveillance pathway;Cell cycle - yeast;Tight junction;Dopaminergic synapse;Chagas disease (American trypanosomiasis);Meiosis - yeast;Long-term depression;TGF-beta signaling pathway
100500919,0,0,0,0,0,0,12,0,0,0,0,0,MIR548Y;microRNA 548y,-,-,-,-
100505475,0,36,0,7,0,0,0,0,0,0,0,0,SYNE1-AS1;SYNE1 antisense RNA 1,-,-,-,-
100505536,0,0,0,0,0,0,0,0,0,26,0,0,ISM1-AS1;ISM1 antisense RNA 1,-,-,-,-
100505549,0,45,42,109,103,0,15,0,0,0,58,0,LOC100505549;uncharacterized LOC100505549,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K01530//Purine metabolism;K11447//Transcriptional misregulation in cancer
100505576,30,0,0,0,0,3,0,0,10,0,0,0,LINC00672;long intergenic non-protein coding RNA 672,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
100505591,0,0,0,0,0,0,0,0,14,1,0,0,LRRC3C;leucine rich repeat containing 3C,GO:0016021//integral component of membrane,-,-,K06850//Axon guidance
100505636,73,0,0,0,0,0,27,0,0,0,0,0,LINC01024;long intergenic non-protein coding RNA 1024,-,-,-,-
100505641,0,1,0,0,0,0,0,0,13,153,0,0,FGD5-AS1;FGD5 antisense RNA 1,-,-,-,K11433//Lysine degradation
100505679,0,0,0,0,0,0,0,0,9,0,0,0,UBE2Q2L;ubiquitin-conjugating enzyme E2Q family member 2-like,-,-,-,K10582//Ubiquitin mediated proteolysis
100505696,320,202,0,29,122,0,80,158,39,2,87,306,SH3BP5-AS1;SH3BP5 antisense RNA 1,-,-,-,-
100505724,0,0,0,0,0,0,21,0,0,0,0,0,KRTAP9-7;keratin associated protein 9-7,GO:0045095//keratin filament,-,-,-
100505738,0,0,0,0,1,28,18,0,5,0,0,0,MIR4458HG;MIR4458 host gene (non-protein coding),-,-,-,-
100505746,0,0,0,0,0,0,69,0,24,29,0,0,ITGB2-AS1;ITGB2 antisense RNA 1,-,-,-,-
100505753,0,0,0,0,0,0,0,0,3,0,1,0,KRTAP16-1;keratin associated protein 16-1,GO:0045095//keratin filament,-,-,K02599//Dorso-ventral axis formation;Notch signaling pathway;Prion diseases;K06252//Focal adhesion;ECM-receptor interaction
100505876,0,0,0,39,120,0,0,0,8,0,0,0,CEBPZOS;CEBPZ opposite strand,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100505879,11,0,0,0,0,0,0,0,0,0,0,0,KIF25-AS1;KIF25 antisense RNA 1,-,-,-,-
100505881,0,0,0,0,18,0,0,0,0,0,0,0,MAGI2-AS3;MAGI2 antisense RNA 3,-,-,-,K05629//Tight junction;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100505989,0,51,0,21,25,0,0,0,0,0,0,0,LINC01207;long intergenic non-protein coding RNA 1207,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100506012,0,0,0,0,0,1,0,0,0,0,0,0,PPP5D1;PPP5 tetratricopeptide repeat domain containing 1,-,-,-,K04460//MAPK signaling pathway
100506033,0,108,3,187,244,0,0,18,0,3,269,167,PTOV1-AS1;PTOV1 antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
100506049,0,0,0,0,0,21,0,0,13,0,0,0,LRRC72;leucine rich repeat containing 72,-,-,-,K11092//Spliceosome
100506060,0,0,0,0,0,10,0,0,4,0,0,113,SMG1P7;SMG1 pseudogene 7,-,-,-,K08873//mRNA surveillance pathway
100506071,0,0,0,0,13,0,0,0,8,0,0,0,LOC100506071;uncharacterized LOC100506071,-,-,-,K08132//Protein digestion and absorption
100506127,0,0,0,0,0,0,0,0,24,0,0,0,LOC100506127;putative uncharacterized protein FLJ37770-like,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
100506144,0,0,0,0,0,1,0,0,19,0,4,0,ZMYM6NB;ZMYM6 neighbor,GO:0016021//integral component of membrane,-,-,-
100506233,0,18,0,5,0,0,0,0,6,0,0,0,RAB30-AS1;RAB30 antisense RNA 1 (head to head),-,-,-,-
100506237,0,0,0,0,0,0,0,0,14,0,0,0,NKX2-1-AS1;NKX2-1 antisense RNA 1,-,-,-,-
100506271,0,0,0,0,0,14,0,0,9,0,0,0,LOC100506271;uncharacterized LOC100506271,-,-,-,-
100506365,0,0,0,4,48,9,0,46,64,0,8,0,OTUD6B-AS1;OTUD6B antisense RNA 1 (head to head),-,-,-,-
100506422,0,0,0,0,0,23,1,0,51,0,10,0,LOC100506422;putative deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323,-,GO:0046080//dUTP metabolic process,GO:0016787//hydrolase activity,-
100506540,0,285,20,446,518,0,35,0,11,0,434,0,SPTY2D1-AS1;SPTY2D1 antisense RNA 1,-,-,-,-
100506581,0,0,0,0,0,0,9,0,0,0,6,0,C16orf95;chromosome 16 open reading frame 95,-,-,-,-
100506585,0,0,0,0,0,0,0,0,0,1,0,223,LOC100506585;uncharacterized LOC100506585,-,-,-,-
100506606,0,0,0,0,0,0,38,0,14,0,0,0,LOC100506606;uncharacterized LOC100506606,-,-,-,"K13356//Peroxisome;Cutin, suberine and wax biosynthesis"
100506627,0,24,63,0,0,0,0,71,68,0,3,0,DCDC5;doublecortin domain containing 5,-,GO:0035556//intracellular signal transduction,-,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
100506649,158,118,54,71,262,5,0,1,19,1,711,0,PXN-AS1;PXN antisense RNA 1,-,-,-,K05760//Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Chemokine signaling pathway;VEGF signaling pathway;Leukocyte transendothelial migration;Focal adhesion
100506650,0,0,0,0,0,9,0,0,3,0,0,0,C17orf112;chromosome 17 open reading frame 112,-,-,-,-
100506658,0,0,0,0,0,0,10,0,4,0,28,0,OCLN;occludin,GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane;GO:0005911//cell-cell junction;GO:0016327//apicolateral plasma membrane,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0070830//tight junction assembly;GO:0045216//cell-cell junction organization;GO:0032259//methylation;GO:0046498//S-adenosylhomocysteine metabolic process;GO:0006461//protein complex assembly;GO:0046500//S-adenosylmethionine metabolic process;GO:0006915//apoptotic process,GO:0019904//protein domain specific binding;GO:0008119//thiopurine S-methyltransferase activity;GO:0005515//protein binding;GO:0005198//structural molecule activity,K06088//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
100506660,0,0,0,0,0,0,29,0,6,0,0,0,DDX11-AS1;DDX11 antisense RNA 1,-,-,-,-
100506680,0,0,0,0,0,0,0,0,37,0,0,0,SACS-AS1;SACS antisense RNA 1,-,-,-,-
100506710,0,23,0,46,76,0,0,0,21,0,15,0,EBLN3;endogenous Bornavirus-like nucleoprotein 3,-,-,-,-
100506714,0,0,0,0,0,16,0,0,0,0,0,0,NUP50-AS1;NUP50 antisense RNA 1 (head to head),-,-,-,-
100506736,0,0,0,0,0,0,0,36,7,0,0,0,SLFN12L;schlafen family member 12-like,GO:0016021//integral component of membrane,-,GO:0005524//ATP binding,-
100506742,245,0,0,0,0,0,0,0,15,0,21,0,CASP12;caspase 12 (gene/pseudogene),GO:0097169//AIM2 inflammasome complex;GO:0005737//cytoplasm;GO:0072559//NLRP3 inflammasome complex;GO:0072557//IPAF inflammasome complex,GO:0097194//execution phase of apoptosis;GO:0050727//regulation of inflammatory response;GO:0042981//regulation of apoptotic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006508//proteolysis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,GO:0004197//cysteine-type endopeptidase activity,K04741//Protein processing in endoplasmic reticulum;Prion diseases;Apoptosis;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease
100506747,0,0,0,0,0,0,22,0,14,0,0,0,"LOC100506747;alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515 homolog",-,-,-,K13748//N-Glycan biosynthesis;Metabolic pathways
100506759,0,0,0,0,0,0,0,0,3,0,0,0,"OR7E37P;olfactory receptor, family 7, subfamily E, member 37 pseudogene",-,-,-,K04257//Olfactory transduction
100506826,0,0,0,11,0,0,0,0,0,0,1,0,MYLK-AS1;MYLK antisense RNA 1,-,-,-,K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
100506866,0,0,49,0,36,27,2,0,73,0,38,0,TTN-AS1;TTN antisense RNA 1,-,-,-,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
100506994,0,0,0,0,0,15,0,0,11,0,0,0,PTPRG-AS1;PTPRG antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
100507003,0,0,0,0,0,1,0,0,1,0,0,0,"GFY;golgi-associated, olfactory signaling regulator",GO:0030173//integral component of Golgi membrane,GO:0050896//response to stimulus;GO:0060271//cilium morphogenesis;GO:0007608//sensory perception of smell,-,K09187//Lysine degradation;K04574//Amyotrophic lateral sclerosis (ALS)
100507034,23,333,357,314,690,0,21,44,17,1,581,0,PITRM1-AS1;PITRM1 antisense RNA 1,-,-,-,-
100507043,0,0,0,0,0,0,0,1,18,0,0,0,TUNAR;TCL1 upstream neural differentiation-associated RNA,-,-,-,-
100507055,0,0,0,0,0,0,0,0,14,0,0,0,LRCOL1;leucine rich colipase-like 1,GO:0005576//extracellular region,GO:0007586//digestion;GO:0043085//positive regulation of catalytic activity;GO:0016042//lipid catabolic process,GO:0008047//enzyme activator activity,-
100507096,0,0,0,0,0,19,0,0,21,0,0,0,GIMD1;GIMAP family P-loop NTPase domain containing 1,-,-,GO:0005525//GTP binding,-
100507156,0,0,0,0,0,11,16,0,28,0,11,0,LOC100507156;uncharacterized LOC100507156,-,-,-,K11447//Transcriptional misregulation in cancer
100507178,2,480,826,337,546,59,164,1951,350,1,863,327,SLFNL1-AS1;SLFNL1 antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer
100507203,0,0,0,0,0,0,0,0,42,39,0,0,SMLR1;small leucine-rich protein 1,GO:0016021//integral component of membrane,-,-,-
100507246,0,2,0,56,146,1,0,0,0,0,0,0,SNHG16;small nucleolar RNA host gene 16 (non-protein coding),-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways
100507290,0,1,0,0,0,0,0,0,12,30,0,212,ZNF865;zinc finger protein 865,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
100507321,0,0,0,24,0,0,0,13,32,0,5,0,"ERVK13-1;endogenous retrovirus group K13, member 1",GO:0016021//integral component of membrane;GO:0019031//viral envelope;GO:0005886//plasma membrane,-,GO:0005198//structural molecule activity,K07987//Natural killer cell mediated cytotoxicity;K00709//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
100507331,65,401,87,451,892,0,20,555,138,230,1272,0,ZSWIM8-AS1;ZSWIM8 antisense RNA 1,-,-,-,-
100507346,0,0,0,37,70,0,0,0,16,0,37,0,LOC100507346;uncharacterized LOC100507346,-,-,-,K06225//Basal cell carcinoma;Pathways in cancer;Hedgehog signaling pathway
100507347,94,3432,429,1830,2729,0,207,8868,201,433,3741,6,VIM-AS1;VIM antisense RNA 1,-,-,-,K07606//Epstein-Barr virus infection
100507412,3043,32,212,11,58,881,1149,2106,2222,6158,441,5590,LOC100507412;uncharacterized LOC100507412,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100507421,88,0,0,15,25,0,25,0,86,0,33,12,TMEM178B;transmembrane protein 178B,GO:0016021//integral component of membrane,-,-,-
100507435,0,0,0,0,0,0,0,36,6,0,0,0,DLGAP2-AS1;DLGAP2 antisense RNA 1,-,-,-,-
100507436,0,0,1,14,5,2,0,4,0,18,34,2,MICA;MHC class I polypeptide-related sequence A,GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0009408//response to heat;GO:0019835//cytolysis;GO:0019882//antigen processing and presentation;GO:0001913//T cell mediated cytotoxicity;GO:0042742//defense response to bacterium;GO:0046629//gamma-delta T cell activation;GO:0006974//cellular response to DNA damage stimulus;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0002418//immune response to tumor cell;GO:0042267//natural killer cell mediated cytotoxicity,GO:0046703//natural killer cell lectin-like receptor binding;GO:0030881//beta-2-microglobulin binding;GO:0005515//protein binding,K07985//Natural killer cell mediated cytotoxicity
100507463,0,0,0,0,0,0,0,0,2,0,0,0,PSMB8-AS1;PSMB8 antisense RNA 1 (head to head),-,-,-,K05653//ABC transporters;Phagosome;Herpes simplex infection;Primary immunodeficiency;Antigen processing and presentation
100507495,0,12,0,14,8,0,0,0,0,0,60,0,SDCBP2-AS1;SDCBP2 antisense RNA 1,-,-,-,-
100507500,181,18,0,19,27,18,0,0,11,0,67,1,EGFR-AS1;EGFR antisense RNA 1,-,-,-,K04361//Calcium signaling pathway;MAPK signaling pathway - fly;Non-small cell lung cancer;Endometrial cancer;Melanoma;Regulation of actin cytoskeleton;Hepatitis C;Glioma;Dorso-ventral axis formation;Focal adhesion;GnRH signaling pathway;Pathways in cancer;Gap junction;Endocytosis;Pancreatic cancer;Prostate cancer;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Bladder cancer;Adherens junction;ErbB signaling pathway;Epithelial cell signaling in Helicobacter pylori infection
100507527,0,0,0,0,0,0,32,0,12,0,0,0,THEG5;testis highly expressed protein 5,-,-,-,-
100507537,0,0,0,0,0,0,0,0,12,0,0,0,LOC100507537;uncharacterized LOC100507537,-,-,-,-
100507547,0,0,0,0,0,0,0,0,0,0,21,0,LOC100507547;uncharacterized LOC100507547,-,-,-,-
100507577,0,191,127,240,337,11,0,225,28,142,274,0,LOC100507577;uncharacterized LOC100507577,-,-,-,K04506//p53 signaling pathway;Ubiquitin mediated proteolysis;Wnt signaling pathway
100507588,0,0,0,0,17,0,38,0,0,0,10,0,"TGFBR3L;transforming growth factor, beta receptor III-like",GO:0016021//integral component of membrane,-,-,K04431//Epstein-Barr virus infection;ErbB signaling pathway;Neurotrophin signaling pathway;Protein processing in endoplasmic reticulum;Osteoclast differentiation;T cell receptor signaling pathway;MAPK signaling pathway;Influenza A;Toll-like receptor signaling pathway;Fc epsilon RI signaling pathway;GnRH signaling pathway
100507600,0,0,0,0,0,0,14,0,0,0,0,0,LOC100507600;uncharacterized LOC100507600,-,-,-,-
100507607,1,0,0,0,0,1,0,73,7,0,0,0,"NPIPB9;nuclear pore complex interacting protein family, member B9",-,-,-,K01896//Lipoic acid metabolism;Metabolic pathways;Butanoate metabolism
100507650,57,8,150,128,89,0,0,68,10,1,78,0,RNF212B;ring finger protein 212B,-,-,GO:0008270//zinc ion binding,-
100507661,0,0,0,0,0,0,0,0,0,0,9,0,LOC100507661;uncharacterized LOC100507661,-,-,-,-
100507679,0,0,0,0,0,0,0,40,31,0,0,0,MUC22;mucin 22,GO:0016021//integral component of membrane,-,-,K06252//ECM-receptor interaction;Focal adhesion
10051,72,0,0,30,10,52,41,0,16,0,0,0,SMC4;structural maintenance of chromosomes 4,GO:0005730//nucleolus;GO:0000796//condensin complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0045132//meiotic chromosome segregation;GO:0051383//kinetochore organization;GO:0000278//mitotic cell cycle;GO:0010032//meiotic chromosome condensation;GO:0007076//mitotic chromosome condensation;GO:0000070//mitotic sister chromatid segregation,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005524//ATP binding,K06675//Cell cycle - yeast
10052,0,0,0,0,0,24,32,0,12,0,14,0,"GJC1;gap junction protein, gamma 1, 45kDa",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0005789//endoplasmic reticulum membrane;GO:0005922//connexon complex;GO:0005921//gap junction,GO:0048738//cardiac muscle tissue development;GO:0007268//synaptic transmission;GO:0061024//membrane organization;GO:0086014//atrial cardiac muscle cell action potential;GO:0006936//muscle contraction;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007601//visual perception;GO:0007043//cell-cell junction assembly;GO:0001570//vasculogenesis;GO:0048468//cell development;GO:0016264//gap junction assembly,GO:0005243//gap junction channel activity;GO:0005216//ion channel activity,-
100526767,0,0,0,0,7,0,0,0,0,0,0,0,RNF103-CHMP3;RNF103-CHMP3 readthrough,-,-,-,K12193//Endocytosis
100526773,0,0,0,0,0,0,0,0,2,0,0,0,EPPIN-WFDC6;EPPIN-WFDC6 readthrough,-,-,-,K02268//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;Cardiac muscle contraction
100526833,0,0,0,0,0,66,16,0,11,110,0,0,SEPT5-GP1BB;SEPT5-GP1BB readthrough,-,-,-,K04557//Parkinson's disease
100527960,0,0,0,0,0,0,0,0,18,0,0,0,MROH7-TTC4;MROH7-TTC4 readthrough (NMD candidate),-,-,-,K09553//Prion diseases
100527964,2,0,35,0,0,6,0,0,12,0,0,222,LHX4-AS1;LHX4 antisense RNA 1,-,-,-,-
100527978,0,0,0,0,0,0,0,0,7,0,0,0,TMEM56-RWDD3;TMEM56-RWDD3 readthrough,-,-,-,-
100528018,0,0,0,0,14,0,0,0,0,0,0,0,ARL2-SNX15;ARL2-SNX15 readthrough (NMD candidate),-,-,-,-
100528032,0,0,0,0,0,13,0,0,0,0,0,0,KLRC4-KLRK1;KLRC4-KLRK1 readthrough,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030101//natural killer cell activation;GO:0007165//signal transduction;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0031295//T cell costimulation;GO:0050776//regulation of immune response;GO:0030154//cell differentiation;GO:0045087//innate immune response,GO:0004872//receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding,K06728//Malaria;Natural killer cell mediated cytotoxicity
100529207,0,0,0,0,0,0,0,0,12,0,0,0,RAD51L3-RFFL;RAD51L3-RFFL readthrough,-,-,-,K10871//Homologous recombination
100529209,0,0,0,0,0,0,0,0,0,0,7,0,RNASEK-C17orf49;RNASEK-C17orf49 readthrough,-,-,-,-
100529261,0,0,0,0,0,0,0,0,0,0,4,0,CHURC1-FNTB;CHURC1-FNTB readthrough,-,-,-,K05954//Terpenoid backbone biosynthesis
100532724,0,0,0,0,0,0,0,0,0,0,0,113,NPHP3-ACAD11;NPHP3-ACAD11 readthrough (NMD candidate),-,-,-,-
100533177,0,0,0,0,0,0,0,0,6,0,0,0,KRTAP29-1;keratin associated protein 29-1,GO:0045095//keratin filament,-,-,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
100533195,0,0,0,0,0,0,20,0,0,0,0,0,FAM24B-CUZD1;FAM24B-CUZD1 readthrough,-,-,-,K13912//Salivary secretion
100533955,0,0,0,0,0,0,3,0,0,0,0,0,SENP3-EIF4A1;SENP3-EIF4A1 readthrough (NMD candidate),-,-,-,-
100533970,0,525,204,312,454,0,0,367,123,178,424,0,P2RX5-TAX1BP3;P2RX5-TAX1BP3 readthrough (NMD candidate),-,-,-,K05219//Neuroactive ligand-receptor interaction;Calcium signaling pathway
100534593,0,0,0,0,0,0,0,0,0,0,2,0,STX16-NPEPL1;STX16-NPEPL1 readthrough (NMD candidate),-,-,-,-
100534611,0,0,0,0,0,0,0,0,12,0,0,0,TM4SF19-TCTEX1D2;TM4SF19-TCTEX1D2 readthrough (NMD candidate),-,-,-,-
100534612,0,0,0,0,0,0,21,0,0,0,0,0,C1QTNF3-AMACR;C1QTNF3-AMACR readthrough (NMD candidate),-,-,-,K01796//Metabolic pathways;Primary bile acid biosynthesis;Peroxisome
10054,79,7,0,34,102,22,0,0,42,0,0,0,UBA2;ubiquitin-like modifier activating enzyme 2,GO:0005829//cytosol;GO:0031510//SUMO activating enzyme complex;GO:0005654//nucleoplasm,GO:0019950//SMT3-dependent protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0016925//protein sumoylation;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding;GO:0019948//SUMO activating enzyme activity;GO:0016874//ligase activity;GO:0005524//ATP binding;GO:0008047//enzyme activator activity,K10685//Ubiquitin mediated proteolysis
10055,0,2,0,8,21,0,6,0,25,0,6,0,SAE1;SUMO1 activating enzyme subunit 1,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0016567//protein ubiquitination;GO:0007346//regulation of mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0016925//protein sumoylation;GO:0043687//post-translational protein modification;GO:0019950//SMT3-dependent protein catabolic process;GO:0043085//positive regulation of catalytic activity,GO:0008022//protein C-terminus binding;GO:0008047//enzyme activator activity;GO:0004839//ubiquitin activating enzyme activity;GO:0019948//SUMO activating enzyme activity;GO:0043008//ATP-dependent protein binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K10684//Ubiquitin mediated proteolysis
10056,0,0,1,12,50,0,0,0,36,124,0,0,"FARSB;phenylalanyl-tRNA synthetase, beta subunit",GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0006412//translation,GO:0004826//phenylalanine-tRNA ligase activity;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K01890//Bacterial secretion system;Aminoacyl-tRNA biosynthesis;ABC transporters
10057,0,21,1,0,2,18,42,32,101,116,21,0,"ABCC5;ATP-binding cassette, sub-family C (CFTR/MRP), member 5",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0055085//transmembrane transport;GO:0015711//organic anion transport;GO:0030213//hyaluronan biosynthetic process;GO:0006810//transport;GO:0030212//hyaluronan metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity;GO:0005524//ATP binding",K05668//ABC transporters
10058,136,0,0,0,0,12,0,0,17,0,11,1,"ABCB6;ATP-binding cassette, sub-family B (MDR/TAP), member 6",GO:0005739//mitochondrion;GO:0005740//mitochondrial envelope;GO:0031307//integral component of mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006810//transport;GO:0043588//skin development;GO:0055085//transmembrane transport;GO:0007420//brain development;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0015886//heme transport;GO:0006879//cellular iron ion homeostasis;GO:0006200//ATP catabolic process,GO:0020037//heme binding;GO:0005524//ATP binding;GO:0015232//heme transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0015439//heme-transporting ATPase activity,K05661//ABC transporters
10059,96,0,123,59,183,17,0,40,25,1,21,0,DNM1L;dynamin 1-like,GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005777//peroxisome;GO:0005905//coated pit;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus,GO:0006184//GTP catabolic process;GO:0061025//membrane fusion;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0032459//regulation of protein oligomerization;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0010821//regulation of mitochondrion organization;GO:0070585//protein localization to mitochondrion;GO:0051289//protein homotetramerization;GO:0070584//mitochondrion morphogenesis;GO:0000266//mitochondrial fission;GO:0016559//peroxisome fission;GO:0090141//positive regulation of mitochondrial fission;GO:0006915//apoptotic process;GO:1900063//regulation of peroxisome organization;GO:0006897//endocytosis;GO:0043065//positive regulation of apoptotic process;GO:0050714//positive regulation of protein secretion;GO:0003374//dynamin polymerization involved in mitochondrial fission;GO:0001836//release of cytochrome c from mitochondria;GO:0090149//membrane fission involved in mitochondrial fission;GO:0070266//necroptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0008289//lipid binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,K01528//Endocytosis;Bacterial invasion of epithelial cells;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
1006,0,0,0,0,0,78,24,0,35,0,0,623,"CDH8;cadherin 8, type 2",GO:0043679//axon terminus;GO:0043083//synaptic cleft;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,"GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0009409//response to cold;GO:0035249//synaptic transmission, glutamatergic",GO:0005509//calcium ion binding,-
10060,0,0,0,0,6,0,64,1,87,4,18,0,"ABCC9;ATP-binding cassette, sub-family C (CFTR/MRP), member 9",GO:0030017//sarcomere;GO:0008076//voltage-gated potassium channel complex;GO:0008282//ATP-sensitive potassium channel complex;GO:0042383//sarcolemma;GO:0005886//plasma membrane,GO:0006813//potassium ion transport;GO:0010107//potassium ion import;GO:0051607//defense response to virus;GO:0007165//signal transduction;GO:0006200//ATP catabolic process;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0005524//ATP binding;GO:0005215//transporter activity;GO:0005267//potassium channel activity;GO:0008281//sulfonylurea receptor activity",K05033//ABC transporters
10061,0,21,0,6,21,31,2,1,28,134,20,0,"ABCF2;ATP-binding cassette, sub-family F (GCN20), member 2",GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0016020//membrane;GO:0005740//mitochondrial envelope,GO:0006810//transport;GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0005524//ATP binding;GO:0005215//transporter activity,-
100616110,0,0,0,0,0,5,0,0,0,0,0,0,MIR2681;microRNA 2681,-,-,-,-
100616111,0,0,0,0,0,0,0,0,36,0,0,0,MIR4455;microRNA 4455,-,-,-,-
100616117,0,0,0,0,0,0,0,1,0,0,0,0,MIR4653;microRNA 4653,-,-,-,-
100616133,0,0,0,0,0,0,0,0,7,0,0,0,MIR4699;microRNA 4699,-,-,-,-
100616134,0,0,0,0,0,0,0,0,15,0,0,0,MIR499B;microRNA 499b,-,-,-,-
100616138,0,0,0,0,0,0,0,0,1,0,0,0,MIR4787;microRNA 4787,-,-,-,-
100616144,0,0,0,0,0,0,27,0,0,0,0,195,MIR548AN;microRNA 548an,-,-,-,-
100616145,0,0,0,0,0,0,0,0,2,0,0,0,MIR1273G;microRNA 1273g,-,-,-,K01557//Tyrosine metabolism;Metabolic pathways;K06264//ECM-receptor interaction
100616146,0,0,0,0,0,0,0,0,1,0,0,0,MIR4534;microRNA 4534,-,-,-,-
100616168,0,0,0,0,13,0,0,0,0,0,0,0,MIR4754;microRNA 4754,-,-,-,-
100616172,2,0,0,0,0,0,0,0,0,0,0,0,MIR4719;microRNA 4719,-,-,-,-
100616175,1,0,0,0,0,0,0,0,0,0,0,0,MIR4633;microRNA 4633,-,-,-,-
100616176,0,0,0,0,0,0,0,0,0,0,6,0,MIR4708;microRNA 4708,-,-,-,-
100616177,0,0,0,0,0,0,0,0,5,0,0,0,MIR4419A;microRNA 4419a,-,-,-,-
100616182,0,0,0,0,0,40,0,0,0,0,0,0,MIR4500;microRNA 4500,-,-,-,-
100616184,0,0,0,0,0,8,0,0,39,0,0,0,MIR4477A;microRNA 4477a,-,-,-,-
100616187,0,0,0,0,0,0,0,0,14,0,0,0,MIR4783;microRNA 4783,-,-,-,-
100616194,0,0,0,0,0,17,0,0,0,0,0,0,MIR4477B;microRNA 4477b,-,-,-,-
100616203,0,0,0,0,0,0,0,0,1,0,0,0,MIR4734;microRNA 4734,-,-,-,-
100616207,0,0,0,0,0,0,0,0,0,0,3,0,MIR4439;microRNA 4439,-,-,-,-
100616212,0,0,0,0,0,0,20,0,0,0,0,0,MIR3689F;microRNA 3689f,-,-,-,-
100616216,0,0,0,0,0,0,0,0,10,0,0,0,MIR4797;microRNA 4797,-,-,-,-
100616218,0,0,0,0,0,0,0,0,0,1,0,0,MIR3135B;microRNA 3135b,-,-,-,-
100616221,0,0,0,0,0,0,0,0,0,0,2,0,MIR4662A;microRNA 4662a,-,-,-,-
100616227,0,0,0,0,0,0,0,0,6,0,0,0,MIR4502;microRNA 4502,-,-,-,-
100616233,0,0,0,0,0,0,0,0,1,0,0,0,MIR4459;microRNA 4459,-,-,-,-
100616234,0,0,0,0,0,15,0,0,9,0,4,0,MIR4454;microRNA 4454,-,-,-,-
100616238,0,0,0,0,0,0,0,0,16,0,0,0,MIR3529;microRNA 3529,-,-,-,-
100616239,0,0,0,0,0,0,0,0,15,0,0,0,MIR4705;microRNA 4705,-,-,-,-
100616246,0,0,0,5,0,0,0,0,7,0,0,0,MIR4799;microRNA 4799,-,-,-,-
100616247,0,0,0,0,0,0,0,0,8,0,0,0,MIR151B;microRNA 151b,-,-,-,-
100616260,0,0,0,0,0,0,0,0,14,0,0,0,MIR4663;microRNA 4663,-,-,-,-
100616261,0,0,0,0,0,0,0,0,18,0,0,0,MIR4504;microRNA 4504,-,-,-,-
100616267,0,0,0,0,0,0,0,0,19,0,0,0,MIR4776-1;microRNA 4776-1,-,-,-,-
100616268,78,0,0,0,0,0,0,0,0,0,0,0,MIR4472-1;microRNA 4472-1,-,-,-,-
100616271,0,0,0,0,0,0,0,0,9,0,0,0,MIR4637;microRNA 4637,-,-,-,-
100616272,0,0,0,0,0,0,0,0,18,0,0,0,MIR4422;microRNA 4422,-,-,-,-
100616277,0,0,0,0,0,6,0,0,0,0,0,0,MIR4522;microRNA 4522,-,-,-,-
100616281,0,0,0,0,0,0,0,0,5,0,0,0,MIR4788;microRNA 4788,-,-,-,-
100616284,0,0,0,0,0,0,0,0,0,0,13,0,MIR4489;microRNA 4489,-,-,-,-
100616288,0,133,2,46,86,0,6,1039,110,133,269,0,MIR4665;microRNA 4665,-,-,-,-
100616289,0,0,0,0,0,0,17,0,0,0,0,0,MIR4475;microRNA 4475,-,-,-,-
100616295,0,0,0,0,0,0,0,0,4,0,0,0,MIR4764;microRNA 4764,-,-,-,-
100616301,0,0,0,0,14,0,0,0,17,0,0,0,MIR4674;microRNA 4674,-,-,-,-
100616302,0,0,0,0,0,0,0,0,1,0,0,0,MIR548X2;microRNA 548x-2,-,-,-,-
100616306,0,0,0,0,0,0,0,0,15,0,0,0,MIR378H;microRNA 378h,-,-,-,-
100616309,0,0,0,0,0,0,0,0,6,0,0,0,MIR4472-2;microRNA 4472-2,-,-,-,-
100616316,0,0,0,0,0,0,3,0,1,0,0,0,MIR4524A;microRNA 4524a,-,-,-,-
100616328,0,0,0,0,0,14,19,0,0,0,0,0,MIR4424;microRNA 4424,-,-,-,-
100616339,0,0,0,0,0,0,0,43,25,0,0,0,MIR548AE2;microRNA 548ae-2,-,-,-,-
100616343,0,0,0,0,0,4,0,0,0,0,0,0,MIR4677;microRNA 4677,-,-,-,-
100616345,0,0,0,0,9,0,0,0,18,0,0,0,MIR4426;microRNA 4426,-,-,-,K02927//Ribosome
100616349,0,0,0,0,0,0,0,0,11,0,0,0,MIR4451;microRNA 4451,-,-,-,-
100616353,0,0,0,0,0,0,0,0,7,0,0,0,MIR4532;microRNA 4532,-,-,-,-
100616362,0,0,0,0,0,0,2,0,0,0,0,0,MIR4533;microRNA 4533,-,-,-,-
100616364,1,0,0,0,0,0,0,0,0,0,0,0,MIR4785;microRNA 4785,-,-,-,-
100616367,0,0,0,0,0,0,0,0,0,0,8,0,MIR4467;microRNA 4467,-,-,-,-
100616371,0,0,1,0,0,0,0,1,8,0,0,0,MIR4746;microRNA 4746,-,-,-,-
100616375,0,0,0,0,0,0,0,0,17,0,0,0,MIR4438;microRNA 4438,-,-,-,-
100616378,0,0,0,0,0,0,0,0,7,0,0,0,MIR4784;microRNA 4784,-,-,-,-
100616383,0,0,0,0,0,0,0,0,13,0,0,0,MIR4675;microRNA 4675,-,-,-,-
100616386,0,0,0,0,0,0,0,0,0,0,7,0,MIR4654;microRNA 4654,-,-,-,-
100616404,0,0,0,0,7,0,0,0,0,0,0,0,MIR4515;microRNA 4515,-,-,-,-
100616410,0,0,0,0,0,0,0,54,0,0,0,0,MIR4692;microRNA 4692,-,-,-,-
100616414,0,0,0,0,0,6,0,0,0,0,0,0,MIR4761;microRNA 4761,-,-,-,-
100616415,0,0,0,0,0,0,0,0,10,0,0,0,MIR4535;microRNA 4535,-,-,-,-
100616417,0,0,0,0,0,0,9,0,0,0,0,0,MIR4786;microRNA 4786,-,-,-,-
100616425,13,0,0,0,0,0,0,0,0,0,0,0,MIR4748;microRNA 4748,-,-,-,-
100616426,0,0,0,0,0,7,0,0,0,0,0,0,MIR4694;microRNA 4694,-,-,-,-
100616427,0,0,0,0,0,0,0,0,6,0,0,0,MIR5096;microRNA 5096,-,-,-,-
100616429,0,0,0,0,0,0,0,0,0,107,0,0,MIR4672;microRNA 4672,-,-,-,-
100616435,0,0,0,0,0,0,0,0,2,0,0,0,MIR4801;microRNA 4801,-,-,-,-
100616436,0,0,0,0,0,0,0,0,0,0,1,0,MIR4449;microRNA 4449,-,-,-,-
100616440,0,0,0,0,0,0,0,47,10,0,0,0,MIR548AG2;microRNA 548ag-2,-,-,-,-
100616454,0,0,0,0,0,0,0,0,4,0,0,0,MIR4497;microRNA 4497,-,-,-,-
100616458,0,21,0,0,2,0,0,6,0,0,0,3,MIR5095;microRNA 5095,-,-,-,-
100616465,0,0,0,0,0,0,0,45,8,0,0,0,MIR4656;microRNA 4656,-,-,-,-
100616469,0,0,0,11,0,0,0,0,0,0,0,0,MIR4429;microRNA 4429,-,-,-,-
100616480,0,0,0,0,0,0,0,0,18,0,0,0,MIR4479;microRNA 4479,-,-,-,-
100616485,0,0,0,0,0,0,0,0,11,0,0,0,MIR4447;microRNA 4447,-,-,-,-
100616486,0,0,0,0,0,0,11,0,0,0,0,0,MIR4698;microRNA 4698,-,-,-,-
100616488,0,0,0,0,0,0,0,0,0,1,0,0,MIR548AK;microRNA 548ak,-,-,-,-
100616492,0,0,0,0,0,0,0,0,0,0,11,0,MIR378F;microRNA 378f,-,-,-,-
100616494,0,0,0,0,0,15,0,0,8,0,0,0,MIR1269B;microRNA 1269b,-,-,-,-
100616499,0,0,0,0,0,0,0,0,0,0,2,0,MIR4435-1;microRNA 4435-1,-,-,-,-
100616668,0,162,80,92,155,25,32,258,91,0,250,0,TPTE2P5;transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 5,-,-,-,-
10062,1,1,0,25,9,26,0,0,30,0,12,0,"NR1H3;nuclear receptor subfamily 1, group H, member 3",GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0032570//response to progesterone;GO:2000188//regulation of cholesterol homeostasis;GO:0043031//negative regulation of macrophage activation;GO:0010875//positive regulation of cholesterol efflux;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0032369//negative regulation of lipid transport;GO:0050728//negative regulation of inflammatory response;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0055092//sterol homeostasis;GO:0045861//negative regulation of proteolysis;GO:0055088//lipid homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0043277//apoptotic cell clearance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090188//negative regulation of pancreatic juice secretion;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0010887//negative regulation of cholesterol storage;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0071222//cellular response to lipopolysaccharide;GO:0070328//triglyceride homeostasis;GO:2000189//positive regulation of cholesterol homeostasis;GO:0030522//intracellular receptor signaling pathway;GO:0090341//negative regulation of secretion of lysosomal enzymes;GO:0048550//negative regulation of pinocytosis;GO:0043401//steroid hormone mediated signaling pathway;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0042632//cholesterol homeostasis;GO:0032376//positive regulation of cholesterol transport;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010467//gene expression;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0015485//cholesterol binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0032810//sterol response element binding;GO:0005515//protein binding,K08536//Hepatitis C;PPAR signaling pathway
100631378,0,44,27,14,15,0,0,0,0,0,33,0,LOC100631378;uncharacterized 100631378,-,-,-,-
100652740,0,37,0,6,71,0,0,467,3,0,132,0,PYCARDOS;PYCARD opposite strand,-,-,-,K12799//Pertussis;Legionellosis;Influenza A;NOD-like receptor signaling pathway;Cytosolic DNA-sensing pathway;Salmonella infection
100652748,1,0,0,0,27,27,0,0,0,0,0,0,TIMM23B;translocase of inner mitochondrial membrane 23 homolog B (yeast),GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane,GO:0071806//protein transmembrane transport;GO:0006886//intracellular protein transport,GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K11447//Transcriptional misregulation in cancer
100652759,0,50,26,72,69,9,22,29,13,0,102,0,PRICKLE2-AS1;PRICKLE2 antisense RNA 1,-,-,-,K04511//Wnt signaling pathway
100652768,0,96,99,121,84,0,27,1,51,0,171,0,LOC100652768;uncharacterized LOC100652768,-,-,-,-
100652772,0,20,0,8,45,6,0,0,6,0,0,0,NNT-AS1;NNT antisense RNA 1,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100652781,0,0,0,0,0,0,0,64,8,3,0,0,SNX29P1;sorting nexin 29 pseudogene 1,-,-,-,K15348//Salmonella infection
100652824,163,0,0,0,0,28,0,0,14,0,0,0,LOC100652824;uncharacterized protein KIAA2012,-,-,-,-
100652846,0,0,0,7,0,4,0,44,0,0,0,0,CACNA1C-AS1;CACNA1C antisense RNA 1,-,-,-,K04850//Long-term potentiation;Serotonergic synapse;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dopaminergic synapse;GnRH signaling pathway;Type II diabetes mellitus;Vascular smooth muscle contraction;MAPK signaling pathway;Glutamatergic synapse;Amphetamine addiction;Cardiac muscle contraction;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Calcium signaling pathway;Cholinergic synapse;GABAergic synapse;Alzheimer's disease;Hypertrophic cardiomyopathy (HCM)
100652883,0,0,0,0,0,1,0,0,13,0,0,0,ALOX15P1;arachidonate 15-lipoxygenase pseudogene 1,-,-,-,K00460//Arachidonic acid metabolism;Linoleic acid metabolism;Metabolic pathways;Serotonergic synapse
100653515,0,0,0,0,0,50,0,0,9,0,0,0,LOC100653515;differential display clone 8,-,-,-,-
10066,0,0,0,0,8,13,10,0,13,0,14,0,SCAMP2;secretory carrier membrane protein 2,GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0032588//trans-Golgi network membrane;GO:0005730//nucleolus;GO:0055038//recycling endosome membrane;GO:0030133//transport vesicle;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0005515//protein binding,K08823//Legionellosis
10067,0,0,0,0,0,11,35,54,0,0,9,0,SCAMP3;secretory carrier membrane protein 3,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0032526//response to retinoic acid;GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0031625//ubiquitin protein ligase binding,K08823//Legionellosis
10068,0,109,88,37,148,0,0,30,44,78,111,1,IL18BP;interleukin 18 binding protein,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:1900116//extracellular negative regulation of signal transduction;GO:0042088//T-helper 1 type immune response;GO:0070301//cellular response to hydrogen peroxide;GO:0032496//response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor,GO:0048019//receptor antagonist activity;GO:0042007//interleukin-18 binding,-
10069,106,0,0,13,126,0,0,0,25,0,0,0,RWDD2B;RWD domain containing 2B,-,-,-,-
1007,0,0,0,0,0,0,0,0,59,0,0,0,"CDH9;cadherin 9, type 2 (T1-cadherin)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0034332//adherens junction organization;GO:0045216//cell-cell junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034329//cell junction assembly;GO:0016337//single organismal cell-cell adhesion,GO:0005509//calcium ion binding,-
10071,7,0,0,0,0,45,32,165,134,11,25,0,"MUC12;mucin 12, cell surface associated",GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane,GO:0001558//regulation of cell growth;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0044267//cellular protein metabolic process,-,-
10072,2,92,35,24,57,0,29,162,41,0,1,0,DPP3;dipeptidyl-peptidase 3,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006508//proteolysis,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0008239//dipeptidyl-peptidase activity,-
10073,0,1,0,0,11,6,0,0,0,0,4,0,SNUPN;snurportin 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005643//nuclear pore,GO:0006606//protein import into nucleus;GO:0000387//spliceosomal snRNP assembly;GO:0034660//ncRNA metabolic process;GO:0061015//snRNA import into nucleus;GO:0016070//RNA metabolic process;GO:0010467//gene expression,GO:0008565//protein transporter activity;GO:0000339//RNA cap binding,K13151//RNA transport
10075,42,208,0,122,438,35,89,85,127,143,4,284,"HUWE1;HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0016574//histone ubiquitination;GO:0006284//base-excision repair;GO:0000209//protein polyubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030154//cell differentiation;GO:0006513//protein monoubiquitination,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0003677//DNA binding,K10592//Ubiquitin mediated proteolysis
100750225,0,0,0,0,9,0,0,0,0,0,0,0,PCAT1;prostate cancer associated transcript 1 (non-protein coding),-,-,-,K11433//Lysine degradation
10076,0,0,0,0,0,50,0,0,35,0,0,0,"PTPRU;protein tyrosine phosphatase, receptor type, U",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,GO:0030336//negative regulation of cell migration;GO:0007155//cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0034394//protein localization to cell surface;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0060070//canonical Wnt signaling pathway;GO:0006470//protein dephosphorylation;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0051384//response to glucocorticoid;GO:0034109//homotypic cell-cell adhesion;GO:0030154//cell differentiation;GO:0031100//organ regeneration,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0008013//beta-catenin binding,-
10077,0,0,0,0,0,0,0,0,30,0,0,0,TSPAN32;tetraspanin 32,GO:0009986//cell surface;GO:0070442//integrin alphaIIb-beta3 complex;GO:0005622//intracellular,GO:0007010//cytoskeleton organization;GO:0008285//negative regulation of cell proliferation;GO:0070527//platelet aggregation;GO:0030886//negative regulation of myeloid dendritic cell activation;GO:0050688//regulation of defense response to virus;GO:0007229//integrin-mediated signaling pathway;GO:0042832//defense response to protozoan;GO:0007267//cell-cell signaling,-,K06508//B cell receptor signaling pathway;Hepatitis C;Malaria
10079,0,0,1,0,55,24,1,10,21,0,6,413,"ATP9A;ATPase, class II, type 9A",GO:0055037//recycling endosome;GO:0005802//trans-Golgi network;GO:0048471//perinuclear region of cytoplasm;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0005769//early endosome,GO:0045332//phospholipid translocation;GO:0008152//metabolic process,GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,K01530//Purine metabolism
1008,0,0,0,0,0,0,13,0,44,0,1,0,"CDH10;cadherin 10, type 2 (T2-cadherin)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0034332//adherens junction organization;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization,GO:0005509//calcium ion binding,-
10081,38,0,1,0,0,0,0,0,10,0,0,0,PDCD7;programmed cell death 7,GO:0005689//U12-type spliceosomal complex,GO:0006915//apoptotic process;GO:0070234//positive regulation of T cell apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0008380//RNA splicing;GO:0051384//response to glucocorticoid,-,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
10082,0,0,1,11,36,5,0,0,9,0,39,0,GPC6;glypican 6,GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0005886//plasma membrane,"GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0007603//phototransduction, visible light;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0016477//cell migration;GO:0001523//retinoid metabolic process;GO:0005975//carbohydrate metabolic process",GO:0043395//heparan sulfate proteoglycan binding,-
10083,0,0,0,0,0,29,0,0,7,309,0,0,"USH1C;Usher syndrome 1C (autosomal recessive, severe)",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0032420//stereocilium;GO:0005829//cytosol,GO:0042472//inner ear morphogenesis;GO:0007605//sensory perception of sound;GO:0050957//equilibrioception;GO:0042491//auditory receptor cell differentiation;GO:0030046//parallel actin filament bundle assembly;GO:0045494//photoreceptor cell maintenance;GO:0000086//G2/M transition of mitotic cell cycle;GO:0050953//sensory perception of light stimulus,GO:0005515//protein binding;GO:0030507//spectrin binding,K06095//Tight junction
10084,0,0,0,0,29,0,0,0,27,0,0,0,PQBP1;polyglutamine binding protein 1,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0071598//neuronal ribonucleoprotein granule;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0048814//regulation of dendrite morphogenesis;GO:0043484//regulation of RNA splicing;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0031175//neuron projection development",GO:0003713//transcription coactivator activity;GO:0043021//ribonucleoprotein complex binding;GO:0003677//DNA binding,K12865//Spliceosome
100847000,0,0,0,0,0,0,0,0,5,0,3,0,MIR5579;microRNA 5579,-,-,-,-
100847004,0,0,0,0,0,0,0,3,0,0,0,0,MIR5188;microRNA 5188,-,-,-,-
100847007,0,0,0,0,0,0,0,0,1,0,0,0,MIR5696;microRNA 5696,-,-,-,-
100847008,0,0,0,0,0,0,0,0,0,0,7,0,MIR4524B;microRNA 4524b,-,-,-,-
100847026,0,0,0,0,0,0,0,0,1,0,0,0,MIR5006;microRNA 5006,-,-,-,-
100847029,49,0,0,0,0,0,0,0,0,0,0,0,MIR5003;microRNA 5003,-,-,-,-
100847030,0,0,0,0,0,13,0,0,0,0,0,0,MIR548AT;microRNA 548at,-,-,-,-
100847031,0,0,0,0,0,0,0,0,9,0,0,0,MIR5700;microRNA 5700,-,-,-,-
100847036,0,0,0,0,0,1,0,0,0,0,0,0,MIR5186;microRNA 5186,-,-,-,-
100847043,78,0,0,0,0,0,0,0,0,0,0,0,MIR5682;microRNA 5682,-,-,-,-
100847044,0,0,0,0,0,0,0,0,26,0,0,0,MIR5087;microRNA 5087,-,-,-,-
100847051,49,0,0,0,0,0,0,0,0,0,2,0,MIR5194;microRNA 5194,-,-,-,-
100847053,0,0,0,0,0,0,0,0,19,0,0,0,MIR5702;microRNA 5702,-,-,-,-
100847055,0,0,18,0,0,0,2,0,0,282,0,0,MIR5697;microRNA 5697,-,-,-,-
100847057,0,0,0,0,0,0,0,0,1,0,0,0,MIR5189;microRNA 5189,-,-,-,-
100847064,0,0,0,0,0,0,0,0,19,0,0,0,MIR5694;microRNA 5694,-,-,-,-
100847066,0,0,0,0,0,0,0,0,14,0,0,0,MIR5692A1;microRNA 5692a-1,-,-,-,-
100847084,0,0,0,0,0,8,0,0,0,0,0,0,MIR548AP;microRNA 548ap,-,-,-,-
100847092,0,0,0,0,0,0,0,0,0,0,18,0,MIR548AS;microRNA 548as,-,-,-,-
10085,0,0,0,0,0,13,23,0,11,0,1,0,EDIL3;EGF-like repeats and discoidin I-like domains 3,GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle,GO:0007275//multicellular organismal development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0007155//cell adhesion,GO:0005509//calcium ion binding;GO:0005178//integrin binding,K03902//Complement and coagulation cascades
10086,0,0,0,0,0,0,0,77,0,0,1,0,HHLA1;HERV-H LTR-associating 1,GO:0005576//extracellular region,-,-,K04928//Cholinergic synapse
100861532,3205,365,119,47,144,725,479,1990,1309,5523,275,16702,"RNA45S5;RNA, 45S pre-ribosomal 5",-,-,-,K05692//Focal adhesion;Vibrio cholerae infection;Gastric acid secretion;Pathogenic Escherichia coli infection;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Phototransduction - fly;Adherens junction;Viral myocarditis;Influenza A;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);K05287//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
100861541,0,0,0,0,0,13,0,0,51,0,0,0,DOCK9-AS2;DOCK9 antisense RNA 2 (head to head),-,-,-,-
100861548,86,1132,1279,1523,1550,1,205,2489,909,1,2420,486,PINK1-AS;PINK1 antisense RNA,-,-,-,K05688//Parkinson's disease
100862671,0,0,0,0,0,39,0,0,0,1,0,1,LOC100862671;uncharacterized LOC100862671,-,-,-,K00871//Insulin signaling pathway;Calcium signaling pathway
100862728,0,0,19,0,6,0,0,0,10,0,9,0,UPK1A-AS1;UPK1A antisense RNA 1,-,-,-,-
10087,71,29,1,35,65,11,0,0,0,0,12,0,"COL4A3BP;collagen, type IV, alpha 3 (Goodpasture antigen) binding protein",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0035621//ER to Golgi ceramide transport;GO:0003007//heart morphogenesis;GO:0007165//signal transduction;GO:0034976//response to endoplasmic reticulum stress;GO:0006936//muscle contraction;GO:0006468//protein phosphorylation;GO:0006665//sphingolipid metabolic process;GO:0007029//endoplasmic reticulum organization;GO:0000902//cell morphogenesis;GO:0006672//ceramide metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0001701//in utero embryonic development;GO:0070584//mitochondrion morphogenesis;GO:0055088//lipid homeostasis;GO:0008283//cell proliferation;GO:0006955//immune response,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0097001//ceramide binding;GO:0035620//ceramide transporter activity,-
100873740,0,0,0,0,0,0,24,0,0,0,0,0,"RNU6-31P;RNA, U6 small nuclear 31, pseudogene",-,-,-,-
100873754,0,0,0,0,0,0,9,0,11,0,0,0,"RNU6-19P;RNA, U6 small nuclear 19, pseudogene",-,-,-,-
100873756,0,0,0,0,2,0,0,0,25,0,0,0,"RNU6-28P;RNA, U6 small nuclear 28, pseudogene",-,-,-,-
100873765,0,0,0,0,0,0,0,0,1,0,0,0,"RNU6-57P;RNA, U6 small nuclear 57, pseudogene",-,-,-,-
100873770,88,0,0,0,0,0,0,0,0,0,0,0,"RNU6-66P;RNA, U6 small nuclear 66, pseudogene",-,-,-,-
100873773,0,0,0,0,0,0,0,0,11,0,0,0,"RNU6-69P;RNA, U6 small nuclear 69, pseudogene",-,-,-,-
100873774,0,0,0,0,0,0,0,0,1,0,0,0,"RNU6-71P;RNA, U6 small nuclear 71, pseudogene",-,-,-,-
100873780,64,0,0,0,0,0,0,0,12,0,0,0,"RNU6-81P;RNA, U6 small nuclear 81, pseudogene",-,-,-,-
100873782,0,10,0,0,0,0,0,0,0,0,4,0,"RNU6-83P;RNA, U6 small nuclear 83, pseudogene",-,-,-,-
100873924,0,0,0,0,0,0,0,0,0,0,11,0,HLX-AS1;HLX antisense RNA 1,-,-,-,-
100873935,1,317,0,177,210,0,0,0,23,0,360,312,MTOR-AS1;MTOR antisense RNA 1,-,-,-,K07203//ErbB signaling pathway;Glioma;Type II diabetes mellitus;Adipocytokine signaling pathway;mTOR signaling pathway;Prostate cancer;Pathways in cancer;Meiosis - yeast;Insulin signaling pathway;Acute myeloid leukemia
100873954,0,167,257,235,354,22,48,72,51,104,563,522,SNRK-AS1;SNRK antisense RNA 1,-,-,-,-
100873969,18,0,0,0,0,0,0,0,0,0,0,0,GPC5-AS1;GPC5 antisense RNA 1,-,-,-,-
100873985,0,0,0,6,11,0,0,78,0,0,5,0,MED14OS;MED14 opposite strand,-,-,-,-
100873989,100,0,0,0,0,28,3,0,30,0,0,0,GRM5-AS1;GRM5 antisense RNA 1,-,-,-,K04604//Glutamatergic synapse;Calcium signaling pathway;Retrograde endocannabinoid signaling;Long-term potentiation;Neuroactive ligand-receptor interaction;Gap junction;Huntington's disease;Long-term depression
100874014,0,40,0,0,16,0,0,0,18,0,0,0,NAV2-AS2;NAV2 antisense RNA 2,-,-,-,-
100874092,0,0,0,0,0,0,0,0,4,0,0,0,UBE2E1-AS1;UBE2E1 antisense RNA 1,-,-,-,-
100874095,0,0,0,0,0,0,0,110,14,0,24,0,ADIPOQ-AS1;ADIPOQ antisense RNA 1,-,-,-,K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus
100874122,0,0,0,5,26,0,0,0,7,0,53,0,FRMPD3-AS1;FRMPD3 antisense RNA 1,-,-,-,-
100874214,0,0,0,0,0,0,0,71,8,0,0,0,TM4SF19-AS1;TM4SF19 antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
100874236,140,0,0,0,0,0,0,0,0,0,0,0,COL18A1-AS2;COL18A1 antisense RNA 2,-,-,-,-
100874259,0,32,0,14,21,16,28,1,43,0,63,0,SLC25A30-AS1;SLC25A30 antisense RNA 1,-,-,-,-
100874261,0,0,0,3,0,0,0,0,0,0,0,0,LINC00854;long intergenic non-protein coding RNA 854,-,-,-,-
100874392,12,0,0,1,0,7,79,0,38,0,0,0,"ANKRD20A12P;ankyrin repeat domain 20 family, member A12, pseudogene",-,-,-,-
100874433,0,0,0,0,0,0,0,0,0,0,5,0,IQCJ-SCHIP1-AS1;IQCJ-SCHIP1 readthrough antisense RNA 1,-,-,-,-
100885776,43,0,0,7,0,0,19,0,23,149,0,0,UGDH-AS1;UGDH antisense RNA 1,-,-,-,K06467//B cell receptor signaling pathway;Cell adhesion molecules (CAMs);Hematopoietic cell lineage;K06478//T cell receptor signaling pathway;Primary immunodeficiency;Cell adhesion molecules (CAMs);Fc gamma R-mediated phagocytosis
100885778,0,0,0,23,0,0,11,0,49,0,1,0,NALCN-AS1;NALCN antisense RNA 1,-,-,-,-
100887750,0,0,0,0,0,0,0,0,9,0,0,0,MRPS31P5;mitochondrial ribosomal protein S31 pseudogene 5,-,-,-,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
10089,0,0,0,0,0,16,0,45,20,0,0,0,"KCNK7;potassium channel, subfamily K, member 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006813//potassium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005267//potassium channel activity;GO:0005244//voltage-gated ion channel activity,-
1009,0,0,0,0,19,25,38,0,39,130,0,0,"CDH11;cadherin 11, type 2, OB-cadherin (osteoblast)",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0045216//cell-cell junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034332//adherens junction organization;GO:0001503//ossification;GO:0021957//corticospinal tract morphogenesis;GO:0034329//cell junction assembly;GO:0007155//cell adhesion;GO:0001501//skeletal system development,GO:0005509//calcium ion binding,-
10090,0,0,0,0,9,10,63,0,80,0,16,0,UST;uronyl-2-sulfotransferase,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0006477//protein sulfation;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process,GO:0008146//sulfotransferase activity,K03193//Glycosaminoglycan biosynthesis - chondroitin sulfate
10092,0,0,0,36,102,0,0,0,11,0,0,107,"ARPC5;actin related protein 2/3 complex, subunit 5, 16kDa",GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0005885//Arp2/3 protein complex;GO:0005829//cytosol;GO:0015629//actin cytoskeleton,GO:0006928//cellular component movement;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0045087//innate immune response,GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding;GO:0005515//protein binding,K05754//Regulation of actin cytoskeleton;Salmonella infection;Bacterial invasion of epithelial cells;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis;Shigellosis
10093,0,206,35,56,56,13,18,367,23,1,99,0,"ARPC4;actin related protein 2/3 complex, subunit 4, 20kDa",GO:0042995//cell projection;GO:0005829//cytosol;GO:0005885//Arp2/3 protein complex;GO:0070062//extracellular vesicular exosome,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0045010//actin nucleation;GO:0045087//innate immune response;GO:0030041//actin filament polymerization,"GO:0019899//enzyme binding;GO:0005200//structural constituent of cytoskeleton;GO:0030674//protein binding, bridging;GO:0005515//protein binding;GO:0051015//actin filament binding",K05755//Shigellosis;Fc gamma R-mediated phagocytosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Salmonella infection;Regulation of actin cytoskeleton
10094,0,61,0,74,54,0,12,0,8,0,0,0,"ARPC3;actin related protein 2/3 complex, subunit 3, 21kDa",GO:0030027//lamellipodium;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0016020//membrane;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0006928//cellular component movement;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045087//innate immune response,GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0051015//actin filament binding,K05756//Regulation of actin cytoskeleton;Salmonella infection;Bacterial invasion of epithelial cells;Shigellosis;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis
10095,0,50,31,4,16,0,23,20,22,0,0,0,"ARPC1B;actin related protein 2/3 complex, subunit 1B, 41kDa",GO:0015629//actin cytoskeleton;GO:0005885//Arp2/3 protein complex;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0006928//cellular component movement,GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding,K05757//Fc gamma R-mediated phagocytosis;Pathogenic Escherichia coli infection;Shigellosis;Salmonella infection;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton
10096,0,0,2,56,209,13,0,3,23,0,3,0,ACTR3;ARP3 actin-related protein 3 homolog (yeast),GO:0005911//cell-cell junction;GO:0030027//lamellipodium;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005885//Arp2/3 protein complex;GO:0002102//podosome;GO:0005925//focal adhesion;GO:0060076//excitatory synapse;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030056//hemidesmosome,GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0051653//spindle localization;GO:0016344//meiotic chromosome movement towards spindle pole;GO:0007163//establishment or maintenance of cell polarity;GO:0008356//asymmetric cell division;GO:0046677//response to antibiotic;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0033206//meiotic cytokinesis;GO:0043519//regulation of myosin II filament organization;GO:0045087//innate immune response;GO:0060271//cilium morphogenesis;GO:0006928//cellular component movement;GO:0010592//positive regulation of lamellipodium assembly;GO:0009743//response to carbohydrate;GO:0045666//positive regulation of neuron differentiation;GO:0051491//positive regulation of filopodium assembly;GO:0050775//positive regulation of dendrite morphogenesis,GO:0005515//protein binding;GO:0051015//actin filament binding;GO:0005524//ATP binding;GO:0005200//structural constituent of cytoskeleton,K05692//Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Gastric acid secretion;Pathogenic Escherichia coli infection;Focal adhesion;Vibrio cholerae infection;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Salmonella infection;Phagosome;Phototransduction - fly;Adherens junction;Viral myocarditis
10097,0,67,2,199,354,7,18,0,9,0,0,0,ACTR2;ARP2 actin-related protein 2 homolog (yeast),GO:0016020//membrane;GO:0030478//actin cap;GO:0005885//Arp2/3 protein complex;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0042995//cell projection,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0033206//meiotic cytokinesis;GO:0045087//innate immune response;GO:0016482//cytoplasmic transport;GO:0006928//cellular component movement;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0051653//spindle localization;GO:0042384//cilium assembly;GO:0016344//meiotic chromosome movement towards spindle pole;GO:0007163//establishment or maintenance of cell polarity;GO:0008356//asymmetric cell division,GO:0005524//ATP binding;GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding,K05692//Phototransduction - fly;Adherens junction;Viral myocarditis;Influenza A;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;K12314//Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM)
10098,0,0,0,0,18,0,36,0,20,0,0,0,TSPAN5;tetraspanin 5,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0051604//protein maturation;GO:0090002//establishment of protein localization to plasma membrane;GO:0045747//positive regulation of Notch signaling pathway,GO:0019899//enzyme binding,-
10099,45,0,0,0,6,0,0,0,44,0,2,0,TSPAN3;tetraspanin 3,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,K06497//Lysosome;K06571//Transcriptional misregulation in cancer
100996255,0,0,0,0,0,2,15,0,0,0,0,0,LOC100996255;uncharacterized LOC100996255,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
100996279,0,0,0,0,0,0,0,0,5,0,0,0,LINC00269;long intergenic non-protein coding RNA 269,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer
100996291,0,0,0,0,0,0,0,0,14,45,17,0,LOC100996291;uncharacterized LOC100996291,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome
100996295,105,59,0,26,8,10,0,205,19,0,20,0,DNAH17-AS1;DNAH17 antisense RNA 1,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion
100996307,0,0,0,0,0,19,0,1,13,0,0,0,LIPE-AS1;LIPE antisense RNA 1,-,-,-,-
100996348,0,0,0,0,0,0,0,0,11,0,0,0,LOC100996348;uncharacterized LOC100996348,-,-,-,K01672//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Nitrogen metabolism;Pancreatic secretion;Collecting duct acid secretion
100996351,60,0,43,38,73,0,0,102,44,0,99,0,LOC100996351;uncharacterized LOC100996351,-,-,-,K04637//Chagas disease (American trypanosomiasis);Calcium signaling pathway;Amoebiasis
100996455,0,0,0,0,0,0,0,0,9,0,0,0,LOC100996455;uncharacterized LOC100996455,-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
100996485,0,189,262,380,266,0,50,116,10,0,776,1,C5orf66;chromosome 5 open reading frame 66,-,-,-,K11251//Systemic lupus erythematosus;Alcoholism
100996492,18,0,0,0,0,0,0,0,10,0,11,0,LINC01314;long intergenic non-protein coding RNA 1314,-,-,-,-
100996634,0,0,0,0,0,7,0,0,18,2,0,0,LOC100996634;transmembrane protein FLJ37396,-,-,-,-
100996648,0,0,0,0,0,1,10,0,0,0,0,5,"TCP11X2;t-complex 11 family, X-linked 2",-,-,-,-
100996693,0,24,0,0,0,0,12,9,25,0,6,0,LOC100996693;CAVP-target protein-like,-,-,-,-
100996702,0,0,0,0,0,0,0,0,14,73,0,0,LINC01356;long intergenic non-protein coding RNA 1356,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
100996712,0,0,0,0,0,0,0,0,4,0,0,0,SRGAP2D;SLIT-ROBO Rho GTPase activating protein 2D (pseudogene),-,-,-,K07526//Axon guidance
101,0,0,1,0,0,0,25,55,20,217,11,0,ADAM8;ADAM metallopeptidase domain 8,GO:0071133//alpha9-beta1 integrin-ADAM8 complex;GO:0070820//tertiary granule;GO:0032010//phagolysosome;GO:0002102//podosome;GO:0005887//integral component of plasma membrane;GO:0071065//alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0032127//dense core granule membrane;GO:0005737//cytoplasm;GO:0042581//specific granule,GO:0070245//positive regulation of thymocyte apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0030198//extracellular matrix organization;GO:2000415//positive regulation of fibronectin-dependent thymocyte migration;GO:0001525//angiogenesis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071456//cellular response to hypoxia;GO:2000391//positive regulation of neutrophil extravasation;GO:0002675//positive regulation of acute inflammatory response;GO:0010954//positive regulation of protein processing;GO:0016337//single organismal cell-cell adhesion;GO:2000309//positive regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0035419//activation of MAPK activity involved in innate immune response;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0048247//lymphocyte chemotaxis;GO:0022617//extracellular matrix disassembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0050714//positive regulation of protein secretion;GO:0006954//inflammatory response;GO:0002523//leukocyte migration involved in inflammatory response;GO:0022407//regulation of cell-cell adhesion;GO:0045785//positive regulation of cell adhesion;GO:0045780//positive regulation of bone resorption;GO:0000902//cell morphogenesis;GO:2000418//positive regulation of eosinophil migration;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0008237//metallopeptidase activity;GO:0043621//protein self-association;GO:0005509//calcium ion binding;GO:0050839//cell adhesion molecule binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
1010,0,0,0,0,0,0,0,2,40,50,0,0,"CDH12;cadherin 12, type 2 (N-cadherin 2)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0034332//adherens junction organization,GO:0005509//calcium ion binding,-
10100,0,0,0,0,0,12,0,0,0,0,0,0,TSPAN2;tetraspanin 2,GO:0043209//myelin sheath;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007420//brain development;GO:0014002//astrocyte development;GO:0042552//myelination;GO:0014005//microglia development;GO:0006954//inflammatory response;GO:0061564//axon development;GO:0048709//oligodendrocyte differentiation,-,K06460//Hematopoietic cell lineage
10101,0,0,28,0,1,0,21,0,8,0,0,0,NUBP2;nucleotide binding protein 2,GO:0031616//spindle pole centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0044281//small molecule metabolic process;GO:0016226//iron-sulfur cluster assembly,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0005515//protein binding",-
10102,0,0,0,10,0,0,18,0,20,0,0,0,"TSFM;Ts translation elongation factor, mitochondrial",GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0006414//translational elongation;GO:0032784//regulation of DNA-templated transcription, elongation",GO:0044822//poly(A) RNA binding;GO:0003746//translation elongation factor activity,-
10103,0,0,0,0,4,0,12,0,0,0,0,0,TSPAN1;tetraspanin 1,GO:0048471//perinuclear region of cytoplasm;GO:0005765//lysosomal membrane;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0045807//positive regulation of endocytosis;GO:0050821//protein stabilization;GO:0008283//cell proliferation;GO:0016477//cell migration;GO:0071934//thiamine transmembrane transport,GO:0005515//protein binding;GO:0015403//thiamine uptake transmembrane transporter activity,K06509//p53 signaling pathway
10105,0,0,0,0,13,0,0,59,0,0,0,1,PPIF;peptidylprolyl isomerase F,GO:0005759//mitochondrial matrix;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016020//membrane,"GO:0070266//necroptotic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0010939//regulation of necrotic cell death;GO:0008637//apoptotic mitochondrial changes;GO:0071243//cellular response to arsenic-containing substance;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0010849//regulation of proton-transporting ATPase activity, rotational mechanism;GO:2000276//negative regulation of oxidative phosphorylation uncoupler activity;GO:0071277//cellular response to calcium ion;GO:0000413//protein peptidyl-prolyl isomerization;GO:0043066//negative regulation of apoptotic process;GO:0090324//negative regulation of oxidative phosphorylation;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0032780//negative regulation of ATPase activity;GO:0006457//protein folding;GO:0002931//response to ischemia;GO:0046902//regulation of mitochondrial membrane permeability;GO:0070301//cellular response to hydrogen peroxide",GO:0005515//protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0016018//cyclosporin A binding,K09565//Calcium signaling pathway;Toxoplasmosis;Huntington's disease;Parkinson's disease
101059918,0,0,0,0,0,0,0,0,6,0,1,0,"GOLGA8R;golgin A8 family, member R",-,-,-,-
10106,72,19,2,6,104,0,38,0,3,172,10,0,"CTDSP2;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2",GO:0005654//nucleoplasm,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006470//protein dephosphorylation,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008420//CTD phosphatase activity,-
101060004,0,0,0,0,0,0,0,0,16,0,0,0,LOC101060004;uncharacterized LOC101060004,-,-,-,-
101060146,39,0,0,0,23,15,7,0,3,0,0,0,"CHMP1B2P;charged multivesicular body protein 1B2, pseudogene",-,-,-,K12197//Endocytosis
101060200,0,0,0,0,0,3,0,0,13,0,0,0,ZNF891;zinc finger protein 891,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
101060211,0,0,0,0,0,1,0,0,17,0,0,0,LOC101060211;cancer/testis antigen family 45 member A5-like,-,-,-,-
10109,0,42,2,60,114,0,0,14,28,0,2,303,"ARPC2;actin related protein 2/3 complex, subunit 2, 34kDa",GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0045202//synapse;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0043005//neuron projection;GO:0005885//Arp2/3 protein complex,GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0045087//innate immune response;GO:0010592//positive regulation of lamellipodium assembly;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006928//cellular component movement;GO:0034314//Arp2/3 complex-mediated actin nucleation,GO:0005515//protein binding;GO:0051015//actin filament binding;GO:0019894//kinesin binding;GO:0035650//AP-1 adaptor complex binding;GO:0071933//Arp2/3 complex binding;GO:0005200//structural constituent of cytoskeleton,K05758//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Salmonella infection;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis;Shigellosis
10110,0,0,0,0,0,0,47,51,7,0,8,0,SGK2;serum/glucocorticoid regulated kinase 2,GO:0005634//nucleus;GO:0005829//cytosol,GO:0034220//ion transmembrane transport;GO:0032411//positive regulation of transporter activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0042127//regulation of cell proliferation;GO:0001558//regulation of cell growth,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0015459//potassium channel regulator activity;GO:0017080//sodium channel regulator activity,-
10111,67,62,57,15,162,50,59,47,103,0,12,0,RAD50;RAD50 homolog (S. cerevisiae),"GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016020//membrane;GO:0000784//nuclear chromosome, telomeric region;GO:0045120//pronucleus;GO:0035861//site of double-strand break;GO:0030870//Mre11 complex;GO:0005654//nucleoplasm","GO:0006302//double-strand break repair;GO:0033674//positive regulation of kinase activity;GO:0006310//DNA recombination;GO:0007004//telomere maintenance via telomerase;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:0000019//regulation of mitotic recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0007131//reciprocal meiotic recombination;GO:0000723//telomere maintenance;GO:0000737//DNA catabolic process, endonucleolytic;GO:0031954//positive regulation of protein autophosphorylation","GO:0003677//DNA binding;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0030674//protein binding, bridging;GO:0008408//3'-5' exonuclease activity;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding",K10866//Homologous recombination;Non-homologous end-joining
10112,0,26,23,10,22,17,20,0,5,0,24,0,KIF20A;kinesin family member 20A,GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0005874//microtubule;GO:0005794//Golgi apparatus;GO:0005871//kinesin complex,GO:0000278//mitotic cell cycle;GO:0015031//protein transport;GO:0008152//metabolic process;GO:0001578//microtubule bundle formation;GO:0006200//ATP catabolic process;GO:0000910//cytokinesis;GO:0007018//microtubule-based movement;GO:0016192//vesicle-mediated transport,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0005524//ATP binding;GO:0005215//transporter activity,-
10113,0,35,27,1,49,6,0,0,11,0,15,0,PREB;prolactin regulatory element binding,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,"GO:0043687//post-translational protein modification;GO:0048208//COPII vesicle coating;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006355//regulation of transcription, DNA-templated;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006351//transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0044267//cellular protein metabolic process",GO:0003677//DNA binding,K14003//Protein processing in endoplasmic reticulum
10114,204,20,3,56,359,13,0,0,49,0,18,0,HIPK3;homeodomain interacting protein kinase 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016605//PML body,"GO:0006355//regulation of transcription, DNA-templated;GO:0009299//mRNA transcription;GO:0018105//peptidyl-serine phosphorylation;GO:0043508//negative regulation of JUN kinase activity;GO:0006915//apoptotic process;GO:0018107//peptidyl-threonine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0006468//protein phosphorylation",GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity,-
10116,0,16,0,54,153,7,26,1,9,0,15,0,FEM1B;fem-1 homolog b (C. elegans),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0016567//protein ubiquitination;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0051438//regulation of ubiquitin-protein transferase activity;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000001//regulation of DNA damage checkpoint;GO:0060442//branching involved in prostate gland morphogenesis;GO:0006915//apoptotic process,GO:0005123//death receptor binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
10117,0,0,0,0,0,0,31,0,47,1,0,703,ENAM;enamelin,GO:0005578//proteinaceous extracellular matrix,GO:0097186//amelogenesis;GO:0031214//biomineral tissue development,-,K03006//Herpes simplex infection;Huntington's disease;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase
101180976,0,0,0,0,0,0,0,0,25,0,35,0,"IFNL4;interferon, lambda 4 (gene/pseudogene)",GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0042502//tyrosine phosphorylation of Stat2 protein;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus,GO:0005125//cytokine activity,K05447//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
1012,156,0,0,9,13,60,22,0,54,0,38,0,CDH13;cadherin 13,GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0043005//neuron projection,GO:0034329//cell junction assembly;GO:0030335//positive regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0043616//keratinocyte proliferation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0030100//regulation of endocytosis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization;GO:0016601//Rac protein signal transduction;GO:0034332//adherens junction organization;GO:0001558//regulation of cell growth;GO:0002040//sprouting angiogenesis;GO:0050927//positive regulation of positive chemotaxis;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030032//lamellipodium assembly;GO:0000278//mitotic cell cycle;GO:0007162//negative regulation of cell adhesion;GO:0051668//localization within membrane;GO:0043542//endothelial cell migration;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0007266//Rho protein signal transduction;GO:0050850//positive regulation of calcium-mediated signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0042058//regulation of epidermal growth factor receptor signaling pathway,GO:0042803//protein homodimerization activity;GO:0045296//cadherin binding;GO:0030169//low-density lipoprotein particle binding;GO:0005509//calcium ion binding;GO:0071813//lipoprotein particle binding;GO:0055100//adiponectin binding,-
10120,1,0,0,15,29,0,18,0,18,0,0,0,"ACTR1B;ARP1 actin-related protein 1 homolog B, centractin beta (yeast)",GO:0016020//membrane;GO:0005829//cytosol;GO:0005869//dynactin complex;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0005515//protein binding;GO:0005524//ATP binding,K05692//Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Gastric acid secretion;Pathogenic Escherichia coli infection;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Adherens junction;Phototransduction - fly
10121,0,33,1,16,115,0,0,22,7,0,34,0,"ACTR1A;ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)",GO:0005875//microtubule associated complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005869//dynactin complex;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0016192//vesicle-mediated transport;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0005524//ATP binding,K05692//Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Gastric acid secretion;Pathogenic Escherichia coli infection;Vibrio cholerae infection;Focal adhesion;Tight junction;Bacterial invasion of epithelial cells;Dilated cardiomyopathy;Shigellosis;Leukocyte transendothelial migration;Viral myocarditis;Adherens junction;Phototransduction - fly;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection;Influenza A
10123,0,0,0,0,0,6,0,0,13,0,0,0,ARL4C;ADP-ribosylation factor-like 4C,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030175//filopodium;GO:0005886//plasma membrane,GO:0032456//endocytic recycling;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding,-
10124,0,0,0,0,8,0,0,0,41,0,0,0,ARL4A;ADP-ribosylation factor-like 4A,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0050873//brown fat cell differentiation;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding,-
101243544,0,0,0,0,0,0,1,0,0,0,0,0,ERCC6-PGBD3;ERCC6-PGBD3 readthrough,-,-,-,K10841//Nucleotide excision repair
10125,17,40,34,0,18,0,17,0,9,0,0,0,RASGRP1;RAS guanyl releasing protein 1 (calcium and DAG-regulated),GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0042629//mast cell granule;GO:0005829//cytosol,GO:0007265//Ras protein signal transduction;GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0032252//secretory granule localization;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0047496//vesicle transport along microtubule;GO:0001816//cytokine production;GO:0002437//inflammatory response to antigenic stimulus;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0007596//blood coagulation;GO:0032862//activation of Rho GTPase activity;GO:0043303//mast cell degranulation,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0008289//lipid binding;GO:0005509//calcium ion binding,K04350//T cell receptor signaling pathway;MAPK signaling pathway
10126,0,24,0,1,33,0,0,0,0,0,0,0,"DNAL4;dynein, axonemal, light chain 4",GO:0005886//plasma membrane;GO:0005929//cilium;GO:0030286//dynein complex;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008152//metabolic process;GO:0007017//microtubule-based process,GO:0003774//motor activity,K10412//Huntington's disease
10127,0,0,0,0,13,0,0,0,69,0,9,0,ZNF263;zinc finger protein 263,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10128,75,106,1,65,116,17,0,0,43,0,7,0,LRPPRC;leucine-rich pentatricopeptide repeat containing,GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0000794//condensed nuclear chromosome;GO:0005637//nuclear inner membrane;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005640//nuclear outer membrane;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0005856//cytoskeleton,"GO:0006351//transcription, DNA-templated;GO:0051028//mRNA transport;GO:0000961//negative regulation of mitochondrial RNA catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0047497//mitochondrion transport along microtubule;GO:0070129//regulation of mitochondrial translation",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008017//microtubule binding;GO:0003697//single-stranded DNA binding;GO:0051015//actin filament binding;GO:0048487//beta-tubulin binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
10129,101,0,0,0,0,52,29,0,156,0,22,0,FRY;furry homolog (Drosophila),GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0005737//cytoplasm,-,-,-
1013,100,0,0,0,0,12,27,0,36,0,0,0,"CDH15;cadherin 15, type 1, M-cadherin (myotubule)",GO:0016021//integral component of membrane;GO:0031594//neuromuscular junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005901//caveola,GO:0051149//positive regulation of muscle cell differentiation;GO:0034332//adherens junction organization;GO:0007155//cell adhesion;GO:0045216//cell-cell junction organization;GO:0042692//muscle cell differentiation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034329//cell junction assembly,GO:0005509//calcium ion binding,K06809//Cell adhesion molecules (CAMs)
10130,3,0,3,24,50,11,17,0,37,0,15,0,"PDIA6;protein disulfide isomerase family A, member 6",GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen,GO:0043277//apoptotic cell clearance;GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006457//protein folding,GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K09584//Protein processing in endoplasmic reticulum
10131,0,31,50,35,77,11,14,52,29,1,41,0,TRAP1;TNF receptor-associated protein 1,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0061077//chaperone-mediated protein folding;GO:1901856//negative regulation of cellular respiration;GO:0034599//cellular response to oxidative stress,GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
10133,0,0,0,18,5,11,6,0,50,0,0,0,OPTN;optineurin,GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007030//Golgi organization;GO:0000042//protein targeting to Golgi;GO:0007165//signal transduction;GO:0050829//defense response to Gram-negative bacterium;GO:0016236//macroautophagy;GO:0090161//Golgi ribbon formation;GO:0043001//Golgi to plasma membrane protein transport;GO:0008219//cell death;GO:0001920//negative regulation of receptor recycling,GO:0005515//protein binding;GO:0031593//polyubiquitin binding;GO:0017137//Rab GTPase binding;GO:0008022//protein C-terminus binding,K07210//NF-kappa B signaling pathway;Pancreatic cancer;Primary immunodeficiency;Chemokine signaling pathway;Pathways in cancer;Toll-like receptor signaling pathway;Small cell lung cancer;Prostate cancer;Chronic myeloid leukemia;Herpes simplex infection;MAPK signaling pathway;T cell receptor signaling pathway;Apoptosis;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;HTLV-I infection;Acute myeloid leukemia;Chagas disease (American trypanosomiasis);Shigellosis;B cell receptor signaling pathway;NOD-like receptor signaling pathway;Cytosolic DNA-sensing pathway;Hepatitis C;Toxoplasmosis;Adipocytokine signaling pathway;Osteoclast differentiation
10134,0,0,0,16,0,12,0,12,12,0,17,0,BCAP31;B-cell receptor-associated protein 31,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007283//spermatogenesis,GO:0005515//protein binding;GO:0042288//MHC class I protein binding;GO:0032403//protein complex binding,K14009//Protein processing in endoplasmic reticulum
101340251,0,0,0,0,0,4,0,0,0,0,0,0,"SNORD124;small nucleolar RNA, C/D box 124",-,-,-,-
10135,0,130,4,157,559,0,48,0,29,0,0,147,NAMPT;nicotinamide phosphoribosyltransferase,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0008286//insulin receptor signaling pathway;GO:0060612//adipose tissue development;GO:0032922//circadian regulation of gene expression;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process;GO:0006766//vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0007165//signal transduction;GO:0006767//water-soluble vitamin metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell proliferation;GO:0006769//nicotinamide metabolic process,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0047280//nicotinamide phosphoribosyltransferase activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity,K03462//Nicotinate and nicotinamide metabolism
10137,0,56,1,38,166,0,8,0,34,0,0,0,RBM12;RNA binding motif protein 12,GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
10138,0,0,0,0,0,0,18,113,163,1,0,0,YAF2;YY1 associated factor 2,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity,-
10139,0,0,0,0,0,10,0,1,45,0,0,0,ARFRP1;ADP-ribosylation factor related protein 1,GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0005794//Golgi apparatus,"GO:0043001//Golgi to plasma membrane protein transport;GO:0007369//gastrulation;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0034067//protein localization to Golgi apparatus;GO:0042147//retrograde transport, endosome to Golgi;GO:0007165//signal transduction",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,-
1014,0,0,0,5,0,15,18,44,15,0,6,0,"CDH16;cadherin 16, KSP-cadherin",GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
10140,0,64,0,22,146,5,0,0,18,0,41,0,"TOB1;transducer of ERBB2, 1",GO:0030014//CCR4-NOT complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008285//negative regulation of cell proliferation;GO:2001141//regulation of RNA biosynthetic process;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0045668//negative regulation of osteoblast differentiation;GO:0060212//negative regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0007184//SMAD protein import into nucleus;GO:0017148//negative regulation of translation;GO:0009967//positive regulation of signal transduction;GO:0030514//negative regulation of BMP signaling pathway",GO:0005515//protein binding;GO:0003714//transcription corepressor activity;GO:0030971//receptor tyrosine kinase binding;GO:0046332//SMAD binding;GO:0005070//SH3/SH2 adaptor activity,K14443//RNA degradation
101410538,0,25,0,1,19,0,0,0,11,0,31,0,MMP24-AS1;MMP24 antisense RNA 1,-,-,-,-
10142,0,0,39,35,43,50,39,64,109,0,4,0,AKAP9;A kinase (PRKA) anchor protein 9,GO:0005856//cytoskeleton;GO:0005813//centrosome;GO:0005794//Golgi apparatus;GO:0036064//ciliary basal body;GO:0008076//voltage-gated potassium channel complex;GO:0000242//pericentriolar material;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0007268//synaptic transmission;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007283//spermatogenesis;GO:0060009//Sertoli cell development;GO:0006810//transport,GO:0032947//protein complex scaffold;GO:0005102//receptor binding;GO:0005515//protein binding;GO:0044325//ion channel binding,-
10143,63,0,0,0,0,0,28,0,0,0,0,0,"CLEC3A;C-type lectin domain family 3, member A",GO:0005576//extracellular region,GO:0001501//skeletal system development,GO:0030246//carbohydrate binding,K03991//Phagosome;Staphylococcus aureus infection;Complement and coagulation cascades;K12589//RNA degradation
10144,63,43,0,29,44,17,3,0,110,0,2,0,"FAM13A;family with sequence similarity 13, member A",GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K08773//Pathways in cancer;Pancreatic cancer;K07526//Axon guidance
10146,117,64,0,54,181,0,0,0,51,0,0,0,G3BP1;GTPase activating protein (SH3 domain) binding protein 1,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule,GO:0006200//ATP catabolic process;GO:0032508//DNA duplex unwinding;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007265//Ras protein signal transduction;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006810//transport,GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding,K12741//Spliceosome
10147,48,35,0,43,134,2,30,0,37,0,3,4,SUGP2;SURP and G patch domain containing 2,GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding,-
10148,0,0,0,0,0,0,0,0,7,0,0,0,EBI3;Epstein-Barr virus induced 3,GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0042088//T-helper 1 type immune response;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0006959//humoral immune response;GO:0045078//positive regulation of interferon-gamma biosynthetic process,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0045523//interleukin-27 receptor binding;GO:0004896//cytokine receptor activity,K05059//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;K05056//Amino sugar and nucleotide sugar metabolism;Galactose metabolism;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway;Metabolic pathways
10149,0,0,13,62,65,1,1,0,45,0,92,0,GPR64;G protein-coupled receptor 64,GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
1015,2,0,0,0,0,1,3,0,28,1,0,0,"CDH17;cadherin 17, LI cadherin (liver-intestine)",GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0006857//oligopeptide transport;GO:0007155//cell adhesion;GO:0035672//oligopeptide transmembrane transport;GO:0006810//transport,GO:0005509//calcium ion binding;GO:0005215//transporter activity;GO:0005427//proton-dependent oligopeptide secondary active transmembrane transporter activity,-
10150,0,1,0,22,54,0,1,0,0,0,0,0,MBNL2;muscleblind-like splicing regulator 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043484//regulation of RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
10151,0,0,0,0,0,3,0,0,16,0,0,0,HNRNPA3P1;heterogeneous nuclear ribonucleoprotein A3 pseudogene 1,-,-,-,K12741//Spliceosome
10152,122,20,31,88,153,45,0,148,119,1,37,1,ABI2;abl-interactor 2,GO:0030175//filopodium;GO:0005829//cytosol;GO:0031209//SCAR complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030027//lamellipodium,GO:0016477//cell migration;GO:0008154//actin polymerization or depolymerization;GO:0016601//Rac protein signal transduction;GO:0006928//cellular component movement;GO:0007010//cytoskeleton organization;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0032403//protein complex binding;GO:0048365//Rac GTPase binding;GO:0070064//proline-rich region binding;GO:0031625//ubiquitin protein ligase binding;GO:0017124//SH3 domain binding;GO:0003677//DNA binding;GO:0019900//kinase binding;GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity,K05751//Regulation of actin cytoskeleton
10153,0,125,212,423,1362,0,0,0,48,0,834,7,"CEBPZ;CCAAT/enhancer binding protein (C/EBP), zeta",GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding,-
10154,0,0,0,0,0,54,61,0,74,0,0,0,PLXNC1;plexin C1,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007165//signal transduction,GO:0005102//receptor binding;GO:0004872//receptor activity;GO:0005515//protein binding,K06572//Axon guidance
10155,0,2,3,17,36,53,0,31,4,0,12,0,TRIM28;tripartite motif containing 28,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005720//nuclear heterochromatin;GO:0005719//nuclear euchromatin,"GO:0006281//DNA repair;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0046777//protein autophosphorylation;GO:0016925//protein sumoylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060669//embryonic placenta morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0051259//protein oligomerization;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016567//protein ubiquitination;GO:1902187//negative regulation of viral release from host cell;GO:0010467//gene expression;GO:0060028//convergent extension involved in axis elongation;GO:0045739//positive regulation of DNA repair;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0016874//ligase activity;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0035851//Krueppel-associated box domain binding;GO:0070087//chromo shadow domain binding,-
10156,0,0,0,0,0,0,0,0,7,0,0,0,RASA4;RAS p21 protein activator 4,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane,GO:0032320//positive regulation of Ras GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0035556//intracellular signal transduction,GO:0005096//GTPase activator activity;GO:0005099//Ras GTPase activator activity;GO:0046872//metal ion binding,K12380//MAPK signaling pathway - fly;K08053//MAPK signaling pathway
10157,78,0,0,0,25,0,3,0,44,0,7,0,AASS;aminoadipate-semialdehyde synthase,GO:0005759//mitochondrial matrix;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process;GO:0051262//protein tetramerization;GO:0034641//cellular nitrogen compound metabolic process;GO:0006554//lysine catabolic process;GO:0044281//small molecule metabolic process;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine,"GO:0047130//saccharopine dehydrogenase (NADP+, L-lysine-forming) activity;GO:0047131//saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity",K14157//Metabolic pathways;Biosynthesis of secondary metabolites;Lysine degradation
10158,0,0,0,0,0,51,23,32,25,0,0,0,PDZK1IP1;PDZK1 interacting protein 1,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
10159,82,6,0,19,0,0,0,0,8,0,13,0,"ATP6AP2;ATPase, H+ transporting, lysosomal accessory protein 2",GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0044297//cell body,GO:0006508//proteolysis;GO:0002003//angiotensin maturation;GO:0044267//cellular protein metabolic process;GO:0043408//regulation of MAPK cascade;GO:0030177//positive regulation of Wnt signaling pathway;GO:0060323//head morphogenesis;GO:0008219//cell death;GO:0048069//eye pigmentation;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0021903//rostrocaudal neural tube patterning,GO:0005515//protein binding;GO:0004190//aspartic-type endopeptidase activity;GO:0004872//receptor activity;GO:0019899//enzyme binding,-
1016,126,0,0,0,0,23,0,0,53,0,10,0,"CDH18;cadherin 18, type 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0045216//cell-cell junction organization;GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034332//adherens junction organization,GO:0005509//calcium ion binding,-
10160,84,34,17,29,41,26,44,80,80,132,0,0,"FARP1;FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)",GO:0030425//dendrite;GO:0045202//synapse;GO:0030175//filopodium;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043197//dendritic spine;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane,GO:0048813//dendrite morphogenesis;GO:0010923//negative regulation of phosphatase activity;GO:0032855//positive regulation of Rac GTPase activity;GO:0032321//positive regulation of Rho GTPase activity;GO:0007416//synapse assembly,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0008092//cytoskeletal protein binding,K06082//Adherens junction
10161,0,0,0,0,0,0,32,0,0,0,0,0,LPAR6;lysophosphatidic acid receptor 6,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,K04273//Neuroactive ligand-receptor interaction
10162,0,64,89,119,183,0,1,65,116,1,121,0,LPCAT3;lysophosphatidylcholine acyltransferase 3,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0097006//regulation of plasma lipoprotein particle levels,GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity,K13515//Glycerophospholipid metabolism
10163,53,40,1,19,159,10,64,136,37,0,38,4,"WASF2;WAS protein family, member 2",GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0030027//lamellipodium;GO:0031209//SCAR complex,GO:0010592//positive regulation of lamellipodium assembly;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0051497//negative regulation of stress fiber assembly;GO:0045087//innate immune response,GO:0003779//actin binding;GO:0032403//protein complex binding;GO:0005515//protein binding,K05748//Salmonella infection;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Adherens junction;Shigellosis
10164,139,0,0,0,0,0,33,0,6,0,0,0,CHST4;carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4,GO:0005802//trans-Golgi network;GO:0031228//intrinsic component of Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0050901//leukocyte tethering or rolling;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0007155//cell adhesion;GO:0006928//cellular component movement;GO:0006477//protein sulfation;GO:0006044//N-acetylglucosamine metabolic process;GO:0006955//immune response,GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity,K04746//Glycosaminoglycan biosynthesis - keratan sulfate
10165,0,0,1,1,43,0,0,5,2,0,6,0,"SLC25A13;solute carrier family 25 (aspartate/glutamate carrier), member 13",GO:0005887//integral component of plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0015813//L-glutamate transport;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006754//ATP biosynthetic process;GO:0051592//response to calcium ion;GO:0055085//transmembrane transport;GO:0015810//aspartate transport;GO:0043490//malate-aspartate shuttle;GO:0006810//transport;GO:0045333//cellular respiration;GO:0006094//gluconeogenesis,GO:0005509//calcium ion binding;GO:0005313//L-glutamate transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0005215//transporter activity,-
10166,6,0,2,33,0,0,0,32,47,0,0,0,SLC25A15;solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0044281//small molecule metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000050//urea cycle;GO:0000066//mitochondrial ornithine transport,GO:0000064//L-ornithine transmembrane transporter activity,-
101669764,0,0,0,0,6,0,0,0,25,0,0,0,GPR1-AS;GPR1 antisense RNA,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
10168,0,15,0,75,31,33,27,39,3,0,0,0,ZNF197;zinc finger protein 197,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10169,0,50,2,81,258,0,0,1,8,0,17,0,SERF2;small EDRK-rich factor 2,GO:0005829//cytosol;GO:0005634//nucleus,-,-,-
1017,0,0,0,16,9,0,0,0,0,0,0,0,CDK2;cyclin-dependent kinase 2,"GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0015030//Cajal body;GO:0000805//X chromosome;GO:0000806//Y chromosome;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0000793//condensed chromosome;GO:0005768//endosome","GO:0000082//G1/S transition of mitotic cell cycle;GO:0071732//cellular response to nitric oxide;GO:0051298//centrosome duplication;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0016572//histone phosphorylation;GO:0007596//blood coagulation;GO:0032298//positive regulation of DNA-dependent DNA replication initiation;GO:0006260//DNA replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0060968//regulation of gene silencing;GO:0008284//positive regulation of cell proliferation;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007265//Ras protein signal transduction;GO:0007126//meiotic nuclear division;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0006813//potassium ion transport",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0005524//ATP binding;GO:0035173//histone kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,K02206//Pathways in cancer;Progesterone-mediated oocyte maturation;Small cell lung cancer;Prostate cancer;Oocyte meiosis;Herpes simplex infection;Cell cycle;Epstein-Barr virus infection;p53 signaling pathway;Measles
10170,0,0,0,0,0,0,25,0,10,0,0,0,DHRS9;dehydrogenase/reductase (SDR family) member 9,GO:0030176//integral component of endoplasmic reticulum membrane,GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0008209//androgen metabolic process;GO:0030855//epithelial cell differentiation;GO:0042572//retinol metabolic process;GO:0055114//oxidation-reduction process;GO:0042448//progesterone metabolic process,GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0004745//retinol dehydrogenase activity;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0016854//racemase and epimerase activity,K11149//Metabolic pathways;Retinol metabolism
10171,0,0,0,0,0,11,0,0,30,0,0,0,RCL1;RNA terminal phosphate cyclase-like 1,GO:0005730//nucleolus,GO:0006396//RNA processing;GO:0042254//ribosome biogenesis,GO:0003824//catalytic activity,K11108//Ribosome biogenesis in eukaryotes
10172,132,0,0,12,10,7,37,0,0,0,0,0,ZNF256;zinc finger protein 256,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
101730217,0,0,0,0,0,0,0,0,9,0,0,0,SPECC1L-ADORA2A;SPECC1L-ADORA2A readthrough (NMD candidate),-,-,-,K04266//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Alcoholism;Vascular smooth muscle contraction
10174,2,0,1,2,42,34,0,62,38,147,0,166,SORBS3;sorbin and SH3 domain containing 3,GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005925//focal adhesion,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007155//cell adhesion;GO:0007015//actin filament organization;GO:0006936//muscle contraction;GO:0051495//positive regulation of cytoskeleton organization;GO:0051496//positive regulation of stress fiber assembly;GO:0031589//cell-substrate adhesion;GO:0043410//positive regulation of MAPK cascade,GO:0017166//vinculin binding;GO:0005200//structural constituent of cytoskeleton;GO:0008134//transcription factor binding;GO:0005515//protein binding,K06086//PPAR signaling pathway;Insulin signaling pathway;Adherens junction
10175,0,0,0,1,16,12,0,0,29,0,0,0,CNIH1;cornichon family AMPA receptor auxiliary protein 1,GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0035556//intracellular signal transduction;GO:0007165//signal transduction;GO:0006955//immune response;GO:0016192//vesicle-mediated transport,-,-
101752399,0,0,0,13,17,0,0,0,0,0,29,0,STAG3L5P-PVRIG2P-PILRB;STAG3L5P-PVRIG2P-PILRB readthrough,-,-,-,K15411//Herpes simplex infection
10178,0,0,0,0,1,34,68,0,112,0,4,1,TENM1;teneurin transmembrane protein 1,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane;GO:0016363//nuclear matrix,"GO:0030838//positive regulation of actin filament polymerization;GO:0051491//positive regulation of filopodium assembly;GO:0043406//positive regulation of MAP kinase activity;GO:0090316//positive regulation of intracellular protein transport;GO:0006351//transcription, DNA-templated;GO:0007218//neuropeptide signaling pathway;GO:0006955//immune response;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007399//nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0006950//response to stress",GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0008201//heparin binding,K06252//Focal adhesion;ECM-receptor interaction
10179,0,0,0,8,26,17,0,0,35,0,11,0,RBM7;RNA binding motif protein 7,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0007126//meiotic nuclear division,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
10180,0,33,0,11,52,16,60,0,48,0,0,0,RBM6;RNA binding motif protein 6,GO:0005634//nucleus,GO:0006396//RNA processing,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003677//DNA binding,-
10181,0,25,45,11,10,8,54,0,30,0,0,0,RBM5;RNA binding motif protein 5,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus,"GO:0006396//RNA processing;GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0008380//RNA splicing",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
10184,0,0,0,0,16,0,17,0,5,0,7,0,LHFPL2;lipoma HMGIC fusion partner-like 2,GO:0016021//integral component of membrane,-,-,-
10186,0,0,0,0,0,0,27,0,0,0,0,0,LHFP;lipoma HMGIC fusion partner,GO:0016021//integral component of membrane,-,GO:0003677//DNA binding,-
10188,54,24,0,16,59,20,35,1,6,0,59,0,"TNK2;tyrosine kinase, non-receptor, 2",GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005905//coated pit;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0030424//axon;GO:0070436//Grb2-EGFR complex,GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007264//small GTPase mediated signal transduction;GO:0016310//phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:2000369//regulation of clathrin-mediated endocytosis;GO:0043086//negative regulation of catalytic activity;GO:0007166//cell surface receptor signaling pathway;GO:0006897//endocytosis,GO:0050699//WW domain binding;GO:0004713//protein tyrosine kinase activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005095//GTPase inhibitor activity;GO:0004674//protein serine/threonine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004712//protein serine/threonine/tyrosine kinase activity,-
10189,0,0,0,0,0,0,0,62,10,0,0,0,ALYREF;Aly/REF export factor,GO:0035145//exon-exon junction complex;GO:0005829//cytosol;GO:0000346//transcription export complex;GO:0016607//nuclear speck;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane,"GO:0031124//mRNA 3'-end processing;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0046784//viral mRNA export from host cell nucleus;GO:0006406//mRNA export from nucleus;GO:0031297//replication fork processing;GO:0001649//osteoblast differentiation;GO:0006369//termination of RNA polymerase II transcription;GO:0000018//regulation of DNA recombination;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K12881//Spliceosome;Herpes simplex infection;RNA transport;mRNA surveillance pathway
1019,0,118,0,11,30,13,0,0,2,0,21,0,CDK4;cyclin-dependent kinase 4,GO:0005667//transcription factor complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005923//tight junction;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0000307//cyclin-dependent protein kinase holoenzyme complex,GO:0051301//cell division;GO:0008284//positive regulation of cell proliferation;GO:0042493//response to drug;GO:0031100//organ regeneration;GO:0009636//response to toxic substance;GO:0045793//positive regulation of cell size;GO:0055093//response to hyperoxia;GO:0033574//response to testosterone;GO:0010288//response to lead ion;GO:0048146//positive regulation of fibroblast proliferation;GO:0071157//negative regulation of cell cycle arrest;GO:0045727//positive regulation of translation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007165//signal transduction;GO:0010468//regulation of gene expression;GO:0007623//circadian rhythm;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0032403//protein complex binding,K02089//Non-small cell lung cancer;T cell receptor signaling pathway;Chronic myeloid leukemia;Melanoma;Bladder cancer;Glioma;p53 signaling pathway;Measles;Cell cycle;Tight junction;Pathways in cancer;HTLV-I infection;Pancreatic cancer;Small cell lung cancer
10190,0,0,0,6,37,14,0,0,0,0,12,0,TXNDC9;thioredoxin domain containing 9,GO:0030496//midbody;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,GO:0045454//cell redox homeostasis,GO:0005515//protein binding,-
101926935,30,0,0,0,0,11,1,2,22,0,13,0,LOC101926935;uncharacterized LOC101926935,-,-,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
101926943,1,721,341,562,1475,0,62,639,154,0,1604,3,LOC101926943;uncharacterized LOC101926943,-,-,-,K03121//Herpes simplex infection;Basal transcription factors
101926963,0,0,0,0,0,0,0,0,22,0,0,39,LOC101926963;uncharacterized LOC101926963,-,-,-,-
101926966,0,0,0,0,0,0,0,0,35,0,0,0,LOC101926966;uncharacterized LOC101926966,-,-,-,-
101926978,0,0,0,0,0,0,0,3,0,0,19,0,LINC01111;long intergenic non-protein coding RNA 1111,-,-,-,-
101927034,0,0,0,0,0,1,0,0,15,0,14,0,ROR1-AS1;ROR1 antisense RNA 1,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K06478//Fc gamma R-mediated phagocytosis;T cell receptor signaling pathway;Primary immunodeficiency;Cell adhesion molecules (CAMs);K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer
101927151,0,0,0,0,6,0,0,0,0,0,0,0,LOC101927151;uncharacterized LOC101927151,-,-,-,-
101927233,0,1,0,17,16,0,0,0,0,0,6,0,CTB-118N6.3;uncharacterized LOC101927233,-,-,-,K06842//Axon guidance
101927267,1,10,307,17,16,37,36,474,70,1,12,275,LOC101927267;uncharacterized LOC101927267,-,-,-,K07607//Amyotrophic lateral sclerosis (ALS)
101927318,0,51,0,0,0,15,22,0,0,0,0,0,LOC101927318;uncharacterized LOC101927318,-,-,-,K09865//Vasopressin-regulated water reabsorption
101927322,0,262,6,236,438,0,26,904,206,4,313,0,LOC101927322;uncharacterized LOC101927322,-,-,-,-
101927374,0,0,0,0,0,0,0,0,29,0,0,1,LOC101927374;uncharacterized LOC101927374,-,-,-,K00543//Tryptophan metabolism;Metabolic pathways;K09299//Transcriptional misregulation in cancer;K04257//Olfactory transduction
101927423,0,47,0,0,18,0,0,86,0,0,23,0,PANO;proapoptotic nucleolar protein,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
101927431,0,0,0,0,0,27,0,0,9,0,6,0,LOC101927431;uncharacterized LOC101927431,-,-,-,-
101927492,0,33,44,51,98,0,0,0,21,295,132,0,LOC101927492;uncharacterized LOC101927492,-,-,-,-
101927550,172,0,0,117,111,0,6,163,0,1,273,1,LOC101927550;uncharacterized LOC101927550,-,-,-,K04678//Endocytosis;TGF-beta signaling pathway;Ubiquitin mediated proteolysis
101927572,76,0,0,0,0,15,0,0,9,0,33,0,LOC101927572;uncharacterized LOC101927572,-,-,-,-
101927583,65,0,0,0,0,36,3,0,19,0,0,0,LOC101927583;uncharacterized LOC101927583,-,-,-,-
101927746,0,0,0,0,0,0,0,0,1,0,0,0,LOC101927746;uncharacterized LOC101927746,-,-,-,-
101927770,0,0,0,0,0,8,0,0,31,0,0,0,LOC101927770;uncharacterized LOC101927770,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
101927844,13,0,0,0,0,0,0,0,7,0,0,0,LOC101927844;uncharacterized LOC101927844,-,-,-,K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
101927905,0,36,21,7,31,0,0,0,0,0,55,0,LOC101927905;uncharacterized LOC101927905,-,-,-,-
101927911,0,52,34,127,123,34,26,3,41,0,127,0,LOC101927911;uncharacterized LOC101927911,-,-,-,-
101927917,0,0,0,0,0,0,1,0,2,0,0,0,LOC101927917;uncharacterized LOC101927917,-,-,-,-
101927919,0,0,0,0,0,0,38,0,13,0,0,0,LOC101927919;uncharacterized LOC101927919,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
101927924,0,0,0,0,0,0,0,0,20,0,0,4,LOC101927924;uncharacterized LOC101927924,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
101927948,0,0,0,0,0,0,0,0,20,0,0,0,LOC101927948;uncharacterized LOC101927948,-,-,-,-
101927954,0,0,0,0,0,0,10,43,9,0,0,0,LOC101927954;uncharacterized LOC101927954,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K05722//Regulation of actin cytoskeleton
101928069,0,79,0,22,34,0,0,92,4,1,45,0,LOC101928069;uncharacterized LOC101928069,-,-,-,-
101928085,0,11,0,0,12,0,0,0,13,0,0,0,ERICH6-AS1;ERICH6 antisense RNA 1,-,-,-,-
101928147,0,22,0,9,33,0,0,0,23,0,5,0,C21orf140;chromosome 21 open reading frame 140,-,-,-,-
101928158,0,0,0,0,1,0,0,0,0,0,19,0,LAMA5-AS1;LAMA5 antisense RNA 1,-,-,-,K06240//Toxoplasmosis;Pathways in cancer;ECM-receptor interaction;Amoebiasis;Small cell lung cancer;Focal adhesion
101928336,0,0,0,0,0,0,0,0,0,0,11,0,LOC101928336;uncharacterized LOC101928336,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
101928340,0,0,0,0,0,0,0,0,12,0,0,0,LOC101928340;uncharacterized LOC101928340,-,-,-,K04257//Olfactory transduction
101928371,0,133,87,117,112,0,0,0,24,0,73,0,LOC101928371;uncharacterized LOC101928371,-,-,-,K08860//Epstein-Barr virus infection;Influenza A;Measles;Hepatitis C;Alzheimer's disease;Protein processing in endoplasmic reticulum;Herpes simplex infection
101928381,2,0,0,0,0,0,28,0,2,0,0,0,LOC101928381;uncharacterized LOC101928381,-,-,-,-
101928416,0,0,0,0,0,0,0,0,5,0,0,0,LOC101928416;uncharacterized LOC101928416,-,-,-,-
101928460,0,0,0,0,0,0,0,114,0,77,0,0,LOC101928460;uncharacterized LOC101928460,-,-,-,-
101928525,1,67,111,96,192,0,39,57,25,0,381,1,LOC101928525;uncharacterized LOC101928525,-,-,-,-
101928597,0,0,0,0,0,0,0,2,0,0,0,0,LOC101928597;uncharacterized LOC101928597,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
101928601,0,0,0,0,0,0,13,0,17,0,0,0,MEI4;meiosis-specific 4 homolog (S. cerevisiae),GO:0000800//lateral element,GO:0042138//meiotic DNA double-strand break formation;GO:0007283//spermatogenesis;GO:0048477//oogenesis;GO:0007129//synapsis;GO:0006310//DNA recombination,-,-
101928603,0,0,0,0,13,0,0,0,7,0,0,0,C6orf229;chromosome 6 open reading frame 229,-,-,-,-
101928710,0,0,0,0,0,0,0,0,8,0,0,0,LOC101928710;uncharacterized LOC101928710,-,-,-,-
101928730,0,0,0,0,0,0,0,0,1,31,0,0,LOC101928730;uncharacterized LOC101928730,-,-,-,-
101928766,102,0,0,0,0,9,17,0,30,0,1,0,LOC101928766;uncharacterized LOC101928766,-,-,-,-
101928786,0,1,0,0,0,21,0,0,14,0,0,0,LOC101928786;uncharacterized LOC101928786,-,-,-,K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
101928796,0,0,0,0,0,0,0,0,21,0,0,0,LOC101928796;uncharacterized LOC101928796,-,-,-,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
101928936,0,0,0,0,0,28,0,0,38,0,0,0,LOC101928936;uncharacterized LOC101928936,-,-,-,-
101928999,0,0,1,10,0,3,0,58,31,1,0,574,IQCF5-AS1;IQCF5 antisense RNA 1,-,-,-,-
101929106,35,0,0,0,0,0,0,0,8,1,8,0,LOC101929106;uncharacterized LOC101929106,-,-,-,-
101929215,0,42,0,35,18,0,68,6,19,0,15,0,CTD-2201I18.1;uncharacterized LOC101929215,-,-,-,K04659//ECM-receptor interaction;Phagosome;Malaria;TGF-beta signaling pathway;Focal adhesion;Bladder cancer;p53 signaling pathway
101929231,0,530,264,727,606,2,48,373,85,1,478,504,LOC101929231;uncharacterized LOC101929231,-,-,-,-
101929268,0,0,0,0,0,11,0,0,0,111,0,0,LOC101929268;uncharacterized LOC101929268,-,-,-,-
101929372,0,114,50,60,116,35,27,83,23,0,132,0,LOC101929372;uncharacterized LOC101929372,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
101929387,13,36,0,24,0,15,22,1,0,0,45,0,LMF1-AS1;LMF1 antisense RNA 1,-,-,-,-
101929390,0,0,24,0,0,0,2,4,0,0,0,0,LINC01247;long intergenic non-protein coding RNA 1247,-,-,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
101929439,0,1,0,12,26,15,17,7,6,0,27,560,LOC101929439;uncharacterized LOC101929439,-,-,-,-
101929532,0,4,0,19,0,1,0,0,4,285,2,0,LOC101929532;uncharacterized LOC101929532,-,-,-,-
101929567,0,0,0,0,0,6,42,84,29,0,16,0,LOC101929567;uncharacterized LOC101929567,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
101929680,0,0,0,0,0,0,0,0,0,0,19,0,LOC101929680;uncharacterized LOC101929680,-,-,-,-
101929780,0,0,0,0,0,0,0,0,11,0,6,0,"NBPF25P;neuroblastoma breakpoint family, member 25, pseudogene",-,-,-,-
10193,0,45,1,8,134,0,0,44,49,0,0,33,"RNF41;ring finger protein 41, E3 ubiquitin protein ligase",GO:0005829//cytosol,GO:0045619//regulation of lymphocyte differentiation;GO:0051865//protein autoubiquitination;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0043408//regulation of MAPK cascade;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0030336//negative regulation of cell migration;GO:0010498//proteasomal protein catabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:2000114//regulation of establishment of cell polarity;GO:0008285//negative regulation of cell proliferation;GO:0051896//regulation of protein kinase B signaling;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045637//regulation of myeloid cell differentiation;GO:0000209//protein polyubiquitination,GO:0016881//acid-amino acid ligase activity;GO:0005135//interleukin-3 receptor binding;GO:0008270//zinc ion binding;GO:0031386//protein tag;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005128//erythropoietin receptor binding,K11981//Endocytosis
10194,0,1,0,1,49,0,0,0,27,0,1,0,TSHZ1;teashirt zinc finger homeobox 1,GO:0005634//nucleus,"GO:0060023//soft palate development;GO:0006355//regulation of transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0042474//middle ear morphogenesis;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
10195,1,0,1,0,0,0,0,0,18,0,0,0,"ALG3;ALG3, alpha-1,3- mannosyltransferase",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0097502//mannosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0006486//protein glycosylation,"GO:0052925//dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0000033//alpha-1,3-mannosyltransferase activity",K03845//N-Glycan biosynthesis;Metabolic pathways;Various types of N-glycan biosynthesis
10196,40,0,0,9,1,11,0,0,1,0,6,223,PRMT3;protein arginine methyltransferase 3,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome,"GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0034969//histone arginine methylation;GO:0031397//negative regulation of protein ubiquitination;GO:0006355//regulation of transcription, DNA-templated",GO:0016274//protein-arginine N-methyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008469//histone-arginine N-methyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0072341//modified amino acid binding;GO:0008168//methyltransferase activity,-
10197,0,22,0,32,83,15,15,0,41,134,0,236,"PSME3;proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)",GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0008537//proteasome activator complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0010950//positive regulation of endopeptidase activity;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0061136//regulation of proteasomal protein catabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I",GO:0005515//protein binding;GO:0002039//p53 binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0061133//endopeptidase activator activity,K06698//Hepatitis C;Antigen processing and presentation;Proteasome
10198,0,0,0,24,39,0,0,0,98,0,16,0,MPHOSPH9;M-phase phosphoprotein 9,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005814//centriole;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005813//centrosome;GO:0005737//cytoplasm,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12478//Phagosome;Endocytosis;Tuberculosis
10199,0,65,1,17,60,14,9,0,13,0,24,0,MPHOSPH10;M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein),GO:0005732//small nucleolar ribonucleoprotein complex;GO:0005694//chromosome;GO:0005730//nucleolus,"GO:0000375//RNA splicing, via transesterification reactions;GO:0010923//negative regulation of phosphatase activity;GO:0006396//RNA processing;GO:0006364//rRNA processing;GO:0008380//RNA splicing",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14559//Ribosome biogenesis in eukaryotes
102,0,0,0,10,22,33,0,0,22,0,11,0,ADAM10;ADAM metallopeptidase domain 10,GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005798//Golgi-associated vesicle;GO:0097038//perinuclear endoplasmic reticulum;GO:0005634//nucleus;GO:0005925//focal adhesion,GO:0030307//positive regulation of cell growth;GO:0006509//membrane protein ectodomain proteolysis;GO:0030335//positive regulation of cell migration;GO:0007220//Notch receptor processing;GO:0001701//in utero embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0008219//cell death;GO:0042117//monocyte activation;GO:0030198//extracellular matrix organization;GO:0007267//cell-cell signaling;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0034612//response to tumor necrosis factor;GO:0010820//positive regulation of T cell chemotaxis;GO:0030574//collagen catabolic process;GO:0007162//negative regulation of cell adhesion;GO:0051089//constitutive protein ectodomain proteolysis;GO:0006468//protein phosphorylation;GO:0022617//extracellular matrix disassembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0007229//integrin-mediated signaling pathway,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0004175//endopeptidase activity;GO:0005102//receptor binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0004222//metalloendopeptidase activity,K06704//Alzheimer's disease;Epithelial cell signaling in Helicobacter pylori infection
1020,0,0,0,0,2,0,20,0,27,79,1,11,CDK5;cyclin-dependent kinase 5,GO:0030425//dendrite;GO:0030175//filopodium;GO:0031594//neuromuscular junction;GO:0016020//membrane;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0043204//perikaryon;GO:0030424//axon;GO:0005634//nucleus;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0016533//cyclin-dependent protein kinase 5 holoenzyme complex;GO:0043025//neuronal cell body;GO:0030027//lamellipodium;GO:0005829//cytosol,"GO:0031175//neuron projection development;GO:0030517//negative regulation of axon extension;GO:0001963//synaptic transmission, dopaminergic;GO:0032801//receptor catabolic process;GO:0070509//calcium ion import;GO:0090314//positive regulation of protein targeting to membrane;GO:0022038//corpus callosum development;GO:0007411//axon guidance;GO:0045055//regulated secretory pathway;GO:0051402//neuron apoptotic process;GO:0048167//regulation of synaptic plasticity;GO:0045860//positive regulation of protein kinase activity;GO:0018105//peptidyl-serine phosphorylation;GO:0042981//regulation of apoptotic process;GO:0048511//rhythmic process;GO:0030182//neuron differentiation;GO:0007160//cell-matrix adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033136//serine phosphorylation of STAT3 protein;GO:0021766//hippocampus development;GO:0007049//cell cycle;GO:0009790//embryo development;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0043525//positive regulation of neuron apoptotic process;GO:0032092//positive regulation of protein binding;GO:0008045//motor neuron axon guidance;GO:0048813//dendrite morphogenesis;GO:1901215//negative regulation of neuron death;GO:0006886//intracellular protein transport;GO:0030334//regulation of cell migration;GO:0007416//synapse assembly;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0006913//nucleocytoplasmic transport;GO:0045786//negative regulation of cell cycle;GO:0019233//sensory perception of pain;GO:0018107//peptidyl-threonine phosphorylation;GO:0071156//regulation of cell cycle arrest;GO:0031914//negative regulation of synaptic plasticity;GO:0007519//skeletal muscle tissue development;GO:0030866//cortical actin cytoskeleton organization;GO:2000273//positive regulation of receptor activity;GO:0051301//cell division;GO:0045861//negative regulation of proteolysis;GO:0014044//Schwann cell development;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0048675//axon extension;GO:0035249//synaptic transmission, glutamatergic;GO:0046777//protein autophosphorylation;GO:0021954//central nervous system neuron development;GO:0016310//phosphorylation;GO:0031397//negative regulation of protein ubiquitination;GO:0007268//synaptic transmission;GO:0048488//synaptic vesicle endocytosis;GO:0048148//behavioral response to cocaine;GO:0043113//receptor clustering;GO:0016079//synaptic vesicle exocytosis;GO:0035418//protein localization to synapse;GO:0008283//cell proliferation;GO:0061001//regulation of dendritic spine morphogenesis;GO:0008542//visual learning;GO:0048709//oligodendrocyte differentiation;GO:0021697//cerebellar cortex formation;GO:0046826//negative regulation of protein export from nucleus;GO:0007596//blood coagulation;GO:0001764//neuron migration;GO:0021819//layer formation in cerebral cortex",GO:0004672//protein kinase activity;GO:0050321//tau-protein kinase activity;GO:0002039//p53 binding;GO:0043125//ErbB-3 class receptor binding;GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0046875//ephrin receptor binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005176//ErbB-2 class receptor binding;GO:0030549//acetylcholine receptor activator activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,K02090//Alzheimer's disease;Axon guidance;Cocaine addiction
10200,0,0,0,0,9,0,0,0,15,0,0,0,MPHOSPH6;M-phase phosphoprotein 6,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0000176//nuclear exosome (RNase complex),GO:0000460//maturation of 5.8S rRNA,GO:0005515//protein binding;GO:0003723//RNA binding,K12593//RNA degradation
10201,0,15,0,7,25,0,17,0,13,0,0,0,NME6;NME/NM23 nucleoside diphosphate kinase 6,GO:0005739//mitochondrion,GO:0006241//CTP biosynthetic process;GO:0045839//negative regulation of mitosis;GO:0006183//GTP biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006915//apoptotic process;GO:0006228//UTP biosynthetic process,GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0046872//metal ion binding,K00940//Metabolic pathways;Bacterial invasion of epithelial cells;Pyrimidine metabolism;Nitrogen metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Shigellosis
10202,0,0,0,0,0,8,31,34,0,108,4,0,DHRS2;dehydrogenase/reductase (SDR family) member 2,GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0034599//cellular response to oxidative stress;GO:0008207//C21-steroid hormone metabolic process;GO:0055114//oxidation-reduction process;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0009636//response to toxic substance;GO:0043011//myeloid dendritic cell differentiation,GO:0004090//carbonyl reductase (NADPH) activity,-
10203,0,0,0,0,0,6,0,0,38,0,8,544,CALCRL;calcitonin receptor-like,GO:0005887//integral component of plasma membrane;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005768//endosome,"GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007507//heart development;GO:0001525//angiogenesis;GO:0071329//cellular response to sucrose stimulus;GO:0006171//cAMP biosynthetic process;GO:0031623//receptor internalization;GO:0006937//regulation of muscle contraction;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0050728//negative regulation of inflammatory response;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0015031//protein transport;GO:0006816//calcium ion transport",GO:0001635//calcitonin gene-related peptide receptor activity;GO:0001605//adrenomedullin receptor activity;GO:0005515//protein binding;GO:0008565//protein transporter activity;GO:0004948//calcitonin receptor activity;GO:0004930//G-protein coupled receptor activity,K04577//Vascular smooth muscle contraction;Neuroactive ligand-receptor interaction
10204,0,0,0,3,6,0,0,0,0,0,0,0,NUTF2;nuclear transport factor 2,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005643//nuclear pore,GO:0006611//protein export from nucleus,GO:0005215//transporter activity;GO:0005515//protein binding,K14285//Ribosome biogenesis in eukaryotes;Influenza A;mRNA surveillance pathway;RNA transport
10205,0,43,0,5,0,0,29,0,20,0,0,0,MPZL2;myelin protein zero-like 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005856//cytoskeleton,GO:0009653//anatomical structure morphogenesis;GO:0033077//T cell differentiation in thymus;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016337//single organismal cell-cell adhesion,GO:0005515//protein binding,K06770//Cell adhesion molecules (CAMs)
10206,0,87,26,14,29,0,13,0,71,0,42,292,TRIM13;tripartite motif containing 13,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0097038//perinuclear endoplasmic reticulum,GO:0016239//positive regulation of macroautophagy;GO:0045087//innate immune response;GO:0051865//protein autoubiquitination;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010942//positive regulation of cell death;GO:0009653//anatomical structure morphogenesis;GO:0010332//response to gamma radiation;GO:1902187//negative regulation of viral release from host cell;GO:0032897//negative regulation of viral transcription,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0004871//signal transducer activity,-
10207,66,189,2,69,299,47,90,40,190,225,3,0,INADL;InaD-like (Drosophila),GO:0016324//apical plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0035556//intracellular signal transduction;GO:0070830//tight junction assembly;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization,GO:0005515//protein binding,K06092//Tight junction
10208,0,1,0,10,0,43,11,0,30,0,0,0,USPL1;ubiquitin specific peptidase like 1,GO:0005615//extracellular space;GO:0015030//Cajal body,GO:0008283//cell proliferation;GO:0016926//protein desumoylation;GO:0006508//proteolysis;GO:0030576//Cajal body organization,GO:0005515//protein binding;GO:0032183//SUMO binding;GO:0070140//SUMO-specific isopeptidase activity;GO:0043130//ubiquitin binding,-
10209,0,216,0,67,105,0,0,1,17,0,0,0,EIF1;eukaryotic translation initiation factor 1,GO:0005737//cytoplasm,GO:0006413//translational initiation;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0006446//regulation of translational initiation;GO:0006950//response to stress,"GO:0008135//translation factor activity, nucleic acid binding;GO:0044822//poly(A) RNA binding;GO:0003743//translation initiation factor activity",K03113//RNA transport
1021,34,2,0,12,87,0,21,0,24,0,1,0,CDK6;cyclin-dependent kinase 6,GO:0005730//nucleolus;GO:0001726//ruffle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm,GO:0050680//negative regulation of epithelial cell proliferation;GO:0021670//lateral ventricle development;GO:0007050//cell cycle arrest;GO:0014002//astrocyte development;GO:2000145//regulation of cell motility;GO:0007219//Notch signaling pathway;GO:0060218//hematopoietic stem cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0043697//cell dedifferentiation;GO:0021542//dentate gyrus development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0033077//T cell differentiation in thymus;GO:0042063//gliogenesis;GO:0000278//mitotic cell cycle;GO:0045668//negative regulation of osteoblast differentiation;GO:0003323//type B pancreatic cell development;GO:0045596//negative regulation of cell differentiation;GO:0010468//regulation of gene expression;GO:0048699//generation of neurons;GO:0045646//regulation of erythrocyte differentiation;GO:2000773//negative regulation of cellular senescence;GO:0051301//cell division;GO:0045638//negative regulation of myeloid cell differentiation;GO:0009615//response to virus;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0001954//positive regulation of cell-matrix adhesion,GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0030332//cyclin binding;GO:0005515//protein binding,K02091//Small cell lung cancer;Pathways in cancer;Pancreatic cancer;Measles;p53 signaling pathway;Glioma;Cell cycle;Non-small cell lung cancer;Melanoma;Chronic myeloid leukemia
10210,0,34,61,52,180,0,4,0,0,0,39,0,"TOPORS;topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase",GO:0016605//PML body;GO:0030496//midbody;GO:0016607//nuclear speck;GO:0005814//centriole;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0000922//spindle pole;GO:0005868//cytoplasmic dynein complex;GO:0036064//ciliary basal body;GO:0000930//gamma-tubulin complex;GO:0000151//ubiquitin ligase complex,"GO:0042127//regulation of cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0051457//maintenance of protein location in nucleus;GO:0046548//retinal rod cell development;GO:0035845//photoreceptor cell outer segment organization;GO:0010842//retina layer formation;GO:0016925//protein sumoylation;GO:0034504//protein localization to nucleus;GO:0046549//retinal cone cell development;GO:0070936//protein K48-linked ubiquitination;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006351//transcription, DNA-templated;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006513//protein monoubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity",GO:0044547//DNA topoisomerase binding;GO:0019789//SUMO ligase activity;GO:0008270//zinc ion binding;GO:0003823//antigen binding;GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
10212,0,0,0,0,0,0,0,0,28,0,0,0,DDX39A;DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004386//helicase activity;GO:0005524//ATP binding,-
10213,0,0,0,3,0,0,0,0,2,0,8,0,"PSMD14;proteasome (prosome, macropain) 26S subunit, non-ATPase, 14","GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0008541//proteasome regulatory particle, lid subcomplex","GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0061136//regulation of proteasomal protein catabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0000724//double-strand break repair via homologous recombination;GO:0006915//apoptotic process;GO:0010950//positive regulation of endopeptidase activity;GO:0044281//small molecule metabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0070536//protein K63-linked deubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination",GO:0061133//endopeptidase activator activity;GO:0004221//ubiquitin thiolesterase activity;GO:0070628//proteasome binding;GO:0008237//metallopeptidase activity;GO:0046872//metal ion binding,K03030//Proteasome;Epstein-Barr virus infection
10215,0,0,0,0,0,0,0,0,31,0,8,0,OLIG2;oligodendrocyte lineage transcription factor 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042552//myelination;GO:0006366//transcription from RNA polymerase II promoter;GO:0021522//spinal cord motor neuron differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021794//thalamus development;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0048663//neuron fate commitment;GO:0048714//positive regulation of oligodendrocyte differentiation,GO:0042803//protein homodimerization activity;GO:0071837//HMG box domain binding;GO:0003677//DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
102157402,0,0,0,0,51,0,0,0,11,0,0,0,AK6;adenylate kinase 6,GO:0005654//nucleoplasm;GO:0015030//Cajal body;GO:0016020//membrane;GO:0005730//nucleolus,GO:0006200//ATP catabolic process;GO:0046939//nucleotide phosphorylation,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0004017//adenylate kinase activity;GO:0005515//protein binding,K14535//Basal transcription factors;Ribosome biogenesis in eukaryotes
10216,0,115,42,44,18,0,28,0,21,1,40,0,PRG4;proteoglycan 4,GO:0005615//extracellular space,GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0042127//regulation of cell proliferation;GO:0006898//receptor-mediated endocytosis;GO:0006955//immune response;GO:0071425//hematopoietic stem cell proliferation;GO:0008283//cell proliferation,GO:0030247//polysaccharide binding;GO:0005044//scavenger receptor activity,K06251//Focal adhesion;ECM-receptor interaction
10217,1,15,2,27,46,8,0,0,77,1,3,695,"CTDSPL;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0004721//phosphoprotein phosphatase activity,-
10218,0,0,0,0,0,0,50,0,39,0,0,0,ANGPTL7;angiopoietin-like 7,GO:0005576//extracellular region,GO:0006979//response to oxidative stress,-,-
1022,0,0,0,20,34,0,0,0,22,0,0,0,CDK7;cyclin-dependent kinase 7,GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm;GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0006200//ATP catabolic process;GO:0050434//positive regulation of viral transcription;GO:0007050//cell cycle arrest;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0010467//gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0051301//cell division;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter",GO:0004672//protein kinase activity;GO:0050681//androgen receptor binding;GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0008022//protein C-terminus binding;GO:0008094//DNA-dependent ATPase activity,K02202//Nucleotide excision repair;Basal transcription factors;Cell cycle
10220,0,122,41,34,96,14,0,0,17,0,78,1,GDF11;growth differentiation factor 11,GO:0005615//extracellular space,GO:0001501//skeletal system development;GO:0045596//negative regulation of cell differentiation;GO:0007498//mesoderm development;GO:0040007//growth;GO:0021512//spinal cord anterior/posterior patterning;GO:0060021//palate development;GO:0031016//pancreas development;GO:0048593//camera-type eye morphogenesis;GO:0007399//nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0048469//cell maturation;GO:0001657//ureteric bud development;GO:0001656//metanephros development,GO:0005125//cytokine activity;GO:0008083//growth factor activity,-
10221,0,0,0,1,7,0,0,0,9,0,0,0,TRIB1;tribbles pseudokinase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043405//regulation of MAP kinase activity;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0007254//JNK cascade;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006469//negative regulation of protein kinase activity;GO:0032496//response to lipopolysaccharide;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0006468//protein phosphorylation;GO:0014912//negative regulation of smooth muscle cell migration,GO:0004860//protein kinase inhibitor activity;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0031625//ubiquitin protein ligase binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0004672//protein kinase activity;GO:0008134//transcription factor binding;GO:0005524//ATP binding,-
10223,0,0,0,0,0,0,29,0,11,0,6,566,GPA33;glycoprotein A33 (transmembrane),GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,-,GO:0004872//receptor activity,-
102238594,11,0,0,0,0,12,0,0,12,0,0,0,SPACA6P-AS;SPACA6P antisense RNA,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
10224,69,0,0,0,0,0,13,0,19,0,13,0,ZNF443;zinc finger protein 443,GO:0005634//nucleus,"GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006950//response to stress",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
10225,0,0,0,0,6,2,0,0,64,0,0,0,CD96;CD96 molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0050776//regulation of immune response;GO:0006955//immune response,-,-
10226,224,1,0,24,57,24,2,0,13,0,0,0,PLIN3;perilipin 3,GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005811//lipid particle;GO:0016020//membrane,GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,K08768//PPAR signaling pathway
10227,0,0,0,0,0,0,0,71,0,0,0,0,MFSD10;major facilitator superfamily domain containing 10,GO:0016021//integral component of membrane,GO:0006915//apoptotic process;GO:0006810//transport;GO:0015904//tetracycline transport;GO:0055085//transmembrane transport,GO:0008493//tetracycline transporter activity,-
10228,0,36,0,31,81,0,0,100,13,0,5,0,STX6;syntaxin 6,GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0031201//SNARE complex;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0032588//trans-Golgi network membrane,"GO:0048193//Golgi vesicle transport;GO:0007032//endosome organization;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport;GO:0006906//vesicle fusion",GO:0005484//SNAP receptor activity;GO:0005515//protein binding,K08498//SNARE interactions in vesicular transport
10229,0,55,0,16,119,0,0,0,0,0,8,0,"COQ7;coenzyme Q7 homolog, ubiquinone (yeast)",GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane,GO:0034599//cellular response to oxidative stress;GO:0022008//neurogenesis;GO:0001701//in utero embryonic development;GO:0070584//mitochondrion morphogenesis;GO:0044281//small molecule metabolic process;GO:0001306//age-dependent response to oxidative stress;GO:0006744//ubiquinone biosynthetic process;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0008340//determination of adult lifespan;GO:0001841//neural tube formation,GO:0046872//metal ion binding,K06134//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
10231,0,0,0,10,19,9,2,0,54,24,0,0,RCAN2;regulator of calcineurin 2,-,GO:0031987//locomotion involved in locomotory behavior;GO:0007614//short-term memory;GO:0033173//calcineurin-NFAT signaling cascade;GO:0006979//response to oxidative stress,GO:0000166//nucleotide binding,-
10232,0,0,0,0,0,0,0,39,11,155,11,0,MSLN;mesothelin,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0009986//cell surface;GO:0005615//extracellular space,GO:0007155//cell adhesion;GO:0031016//pancreas development,GO:0005515//protein binding,-
10233,0,0,0,6,0,0,0,0,2,0,9,0,LRRC23;leucine rich repeat containing 23,-,-,-,K11092//Spliceosome;K10159//Chagas disease (American trypanosomiasis);Malaria;Rheumatoid arthritis;Phagosome;Legionellosis;Tuberculosis;Toll-like receptor signaling pathway;Herpes simplex infection;Leishmaniasis;Toxoplasmosis;Measles;Amoebiasis;K10411//Huntington's disease
10234,0,0,0,0,0,17,0,108,25,0,0,0,LRRC17;leucine rich repeat containing 17,GO:0005615//extracellular space,GO:0033687//osteoblast proliferation;GO:0001649//osteoblast differentiation;GO:0045671//negative regulation of osteoclast differentiation;GO:0048539//bone marrow development,-,K06839//Axon guidance
10235,0,0,0,0,0,2,11,50,31,0,2,0,RASGRP2;RAS guanyl releasing protein 2 (calcium and DAG-regulated),GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0032587//ruffle membrane,GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0030168//platelet activation;GO:0007265//Ras protein signal transduction;GO:0001558//regulation of cell growth;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007596//blood coagulation,GO:0005509//calcium ion binding;GO:0008289//lipid binding;GO:0019992//diacylglycerol binding;GO:0005085//guanyl-nucleotide exchange factor activity,K12361//MAPK signaling pathway;Chemokine signaling pathway;K00688//Starch and sucrose metabolism;Insulin signaling pathway
10236,0,17,2,59,361,0,15,0,19,0,0,0,HNRNPR;heterogeneous nuclear ribonucleoprotein R,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
10237,14,0,0,0,12,0,0,0,19,0,0,0,"SLC35B1;solute carrier family 35, member B1",GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0006810//transport;GO:0072334//UDP-galactose transmembrane transport,GO:0005459//UDP-galactose transmembrane transporter activity,-
10238,81,136,20,54,237,16,71,0,21,0,0,19,DCAF7;DDB1 and CUL4 associated factor 7,GO:0005730//nucleolus;GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0043234//protein complex,GO:0016567//protein ubiquitination;GO:0007275//multicellular organismal development,GO:0005515//protein binding,-
10239,0,1,63,7,40,0,0,0,0,0,0,0,"AP3S2;adaptor-related protein complex 3, sigma 2 subunit",GO:0030123//AP-3 adaptor complex;GO:0005794//Golgi apparatus;GO:0030659//cytoplasmic vesicle membrane,GO:0006886//intracellular protein transport;GO:0048490//anterograde synaptic vesicle transport;GO:0008089//anterograde axon cargo transport,GO:0008565//protein transporter activity,K12399//Lysosome
1024,0,0,0,22,22,0,39,0,47,0,0,0,CDK8;cyclin-dependent kinase 8,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016592//mediator complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0010467//gene expression;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle",GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0005524//ATP binding,-
10240,0,0,0,10,1,0,0,0,0,0,2,0,MRPS31;mitochondrial ribosomal protein S31,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005763//mitochondrial small ribosomal subunit,-,GO:0019904//protein domain specific binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,-
10241,0,89,3,39,97,0,14,0,7,0,0,0,CALCOCO2;calcium binding and coiled-coil domain 2,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0016032//viral process;GO:0034341//response to interferon-gamma,GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K15010//Glutamatergic synapse;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
10242,0,0,0,0,19,0,0,0,19,0,0,0,"KCNMB2;potassium large conductance calcium-activated channel, subfamily M, beta member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0019229//regulation of vasoconstriction;GO:0006813//potassium ion transport;GO:0007596//blood coagulation;GO:0005513//detection of calcium ion;GO:0001508//action potential,GO:0015269//calcium-activated potassium channel activity;GO:0008200//ion channel inhibitor activity;GO:0015459//potassium channel regulator activity,K04938//Vascular smooth muscle contraction
10243,0,29,1,8,9,23,0,0,10,0,17,0,GPHN;gephyrin,GO:0005737//cytoplasm;GO:0060077//inhibitory synapse;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0007529//establishment of synaptic specificity at neuromuscular junction;GO:0006766//vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0061599//molybdopterin molybdotransferase activity;GO:0061598//molybdopterin adenylyltransferase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0016740//transferase activity,K15376//GABAergic synapse
10244,0,66,0,0,0,21,0,0,17,0,0,0,RABEPK;Rab9 effector protein with kelch motifs,GO:0005886//plasma membrane;GO:0005768//endosome;GO:0010008//endosome membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0006904//vesicle docking involved in exocytosis;GO:0006898//receptor-mediated endocytosis,-,K14966//Herpes simplex infection
10245,0,239,90,93,94,0,46,0,43,0,189,0,TIMM17B;translocase of inner mitochondrial membrane 17 homolog B (yeast),GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0031305//integral component of mitochondrial inner membrane,GO:0006626//protein targeting to mitochondrion;GO:0071806//protein transmembrane transport;GO:0044267//cellular protein metabolic process,GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity,-
10246,0,0,0,0,0,0,0,0,30,119,0,307,"SLC17A2;solute carrier family 17, member 2",GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0006814//sodium ion transport;GO:0035435//phosphate ion transmembrane transport;GO:0006796//phosphate-containing compound metabolic process;GO:0035725//sodium ion transmembrane transport,GO:0005436//sodium:phosphate symporter activity,-
102464823,43,0,0,0,0,0,0,0,0,0,0,0,MIR6068;microRNA 6068,-,-,-,-
102464824,113,0,0,0,0,0,0,0,0,0,0,0,MIR6069;microRNA 6069,-,-,-,-
102464825,0,0,0,0,0,0,0,0,1,0,0,0,MIR6070;microRNA 6070,-,-,-,-
102464828,0,0,0,0,0,0,0,0,10,0,0,0,MIR6076;microRNA 6076,-,-,-,-
102464830,0,0,0,0,0,0,0,0,26,0,0,0,MIR6079;microRNA 6079,-,-,-,-
102464834,0,0,0,0,0,26,0,0,0,0,0,0,MIR6085;microRNA 6085,-,-,-,-
102464836,0,0,0,0,0,0,0,0,0,0,10,0,MIR6088;microRNA 6088,-,-,-,-
102465134,0,85,3,82,117,0,0,39,0,0,238,1,MIR6126;microRNA 6126,-,-,-,-
102465140,0,0,0,0,0,0,0,0,6,0,0,0,MIR6134;microRNA 6134,-,-,-,-
102465141,1,0,0,0,0,0,0,0,0,0,0,0,MIR6165;microRNA 6165,-,-,-,-
102465247,0,0,0,0,0,12,0,0,0,0,0,0,MIR548AY;microRNA 548ay,-,-,-,-
102465255,0,0,0,0,0,0,10,0,0,0,0,0,MIR6512;microRNA 6512,-,-,-,-
102465432,2,0,2,0,4,0,0,0,0,0,0,1,MIR6723;microRNA 6723,-,-,-,K02256//Cardiac muscle contraction;Metabolic pathways;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease
102465452,0,0,0,0,0,0,0,0,0,0,3,0,MIR6755;microRNA 6755,-,-,-,-
102465507,0,0,0,0,0,0,0,0,10,0,0,0,MIR6842;microRNA 6842,-,-,-,-
102465694,0,0,0,0,0,1,18,0,0,0,0,0,MIR7161;microRNA 7161,-,-,-,-
102465753,0,0,0,0,0,0,0,0,19,67,0,0,MIR7641-2;microRNA 7641-2,-,-,-,-
102465842,0,0,0,0,0,0,0,0,11,0,0,0,MIR7856;microRNA 7856,-,-,-,-
102465856,0,0,0,0,0,0,14,0,0,0,0,0,MIR7974;microRNA 7974,-,-,-,-
102465860,0,0,0,0,0,0,0,0,13,0,0,0,MIR8054;microRNA 8054,-,-,-,-
102465861,0,0,0,0,0,0,0,0,22,0,0,0,MIR8055;microRNA 8055,-,-,-,-
102465862,0,0,0,0,0,0,0,4,0,0,0,0,MIR8056;microRNA 8056,-,-,-,-
102465865,0,0,0,0,0,0,0,0,11,0,0,0,MIR8062;microRNA 8062,-,-,-,-
102465870,0,0,0,0,0,0,3,0,0,0,0,0,MIR8070;microRNA 8070,-,-,-,-
102465876,0,0,0,0,0,0,0,0,20,0,0,0,MIR8079;microRNA 8079,-,-,-,-
102465881,0,0,0,4,0,0,0,0,0,0,1,0,MIR8087;microRNA 8087,-,-,-,-
102465944,49,0,0,0,0,0,0,0,0,0,0,0,MIR6072;microRNA 6072,-,-,-,-
102466081,0,0,0,0,0,0,21,0,0,0,0,0,MIR5739;microRNA 5739,-,-,-,-
102466162,0,0,0,0,0,0,0,0,0,0,0,2,MIR548AZ;microRNA 548az,-,-,-,-
102466225,0,0,0,0,0,0,0,0,1,0,0,0,MIR6077;microRNA 6077,-,-,-,-
102466235,0,0,0,1,0,0,0,0,0,0,0,0,MIR7515;microRNA 7515,-,-,-,-
102466247,0,0,0,0,6,0,0,0,0,0,0,0,MIR1273H;microRNA 1273h,-,-,-,-
102466252,0,0,0,0,0,0,0,0,0,117,0,0,MIR8069-1;microRNA 8069-1,-,-,-,-
102466721,0,0,0,0,0,0,0,0,0,0,4,0,MIR892C;microRNA 892c,-,-,-,-
102466732,0,0,0,0,0,0,0,0,29,0,0,0,MIR6774;microRNA 6774,-,-,-,-
102466737,0,0,0,0,0,21,0,0,0,0,0,0,MIR6793;microRNA 6793,-,-,-,-
102466812,0,0,0,0,0,0,0,0,1,0,0,0,MIR6511A2;microRNA 6511a-2,-,-,-,-
102466866,0,0,0,0,0,0,47,0,17,0,0,0,MIR7853;microRNA 7853,-,-,-,-
102466878,78,36,185,19,9,2,2,1406,270,1,44,24,MIR8078;microRNA 8078,-,-,-,-
102466880,0,0,0,0,0,0,0,0,16,0,0,0,MIR8088;microRNA 8088,-,-,-,-
102466918,153,0,0,0,0,0,0,0,0,0,0,0,MIR8059;microRNA 8059,-,-,-,-
102467003,0,0,0,0,0,0,0,0,1,0,0,0,MIR7851;microRNA 7851,-,-,-,-
10247,39,0,0,5,24,36,0,0,3,0,0,0,HRSP12;heat-responsive protein 12,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006449//regulation of translational termination;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0019239//deaminase activity;GO:0044822//poly(A) RNA binding;GO:0004519//endonuclease activity,K02908//Ribosome
10248,60,0,0,0,0,0,0,0,6,0,0,0,"POP7;processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)",GO:0005655//nucleolar ribonuclease P complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004526//ribonuclease P activity,K14527//Ribosome biogenesis in eukaryotes;RNA transport
10249,0,0,0,0,0,5,0,0,13,0,0,0,GLYAT;glycine-N-acyltransferase,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005759//mitochondrial matrix,GO:0006544//glycine metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0032787//monocarboxylic acid metabolic process;GO:0006637//acyl-CoA metabolic process,"GO:0047961//glycine N-acyltransferase activity;GO:0047962//glycine N-benzoyltransferase activity;GO:0016746//transferase activity, transferring acyl groups",K00628//Phenylalanine metabolism;K15517//Phenylalanine metabolism
1025,0,16,0,0,9,0,0,54,60,0,0,0,CDK9;cyclin-dependent kinase 9,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016605//PML body;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0008024//positive transcription elongation factor complex b;GO:0005654//nucleoplasm;GO:0008023//transcription elongation factor complex;GO:0016020//membrane,"GO:0006282//regulation of DNA repair;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0043111//replication fork arrest;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008283//cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0071157//negative regulation of cell cycle arrest;GO:0010467//gene expression;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071345//cellular response to cytokine stimulus;GO:0006281//DNA repair;GO:0031056//regulation of histone modification;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation",GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0017069//snRNA binding;GO:0005515//protein binding,K02211//Transcriptional misregulation in cancer
10250,0,3,0,59,355,0,52,24,52,0,5,0,SRRM1;serine/arginine repetitive matrix 1,GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0016607//nuclear speck,"GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0031124//mRNA 3'-end processing;GO:0006406//mRNA export from nucleus",GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding,K13171//RNA transport;mRNA surveillance pathway
10251,58,0,0,0,0,7,60,0,30,0,0,0,SPRY3;sprouty homolog 3 (Drosophila),GO:0016020//membrane;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0009966//regulation of signal transduction,-,K04704//Jak-STAT signaling pathway
10252,0,0,0,0,5,23,0,23,0,0,7,0,"SPRY1;sprouty homolog 1, antagonist of FGF signaling (Drosophila)",GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007275//multicellular organismal development,GO:0005515//protein binding,K04704//Jak-STAT signaling pathway
10253,0,0,32,0,1,12,42,0,0,0,0,0,SPRY2;sprouty homolog 2 (Drosophila),GO:0005874//microtubule;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0000132//establishment of mitotic spindle orientation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043407//negative regulation of MAP kinase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0060437//lung growth;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0046580//negative regulation of Ras protein signal transduction;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0034261//negative regulation of Ras GTPase activity;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060449//bud elongation involved in lung branching;GO:0042472//inner ear morphogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0007605//sensory perception of sound;GO:0045165//cell fate commitment;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0030291//protein serine/threonine kinase inhibitor activity,K04704//Jak-STAT signaling pathway
10254,19,95,1,55,86,9,14,55,104,141,22,3,STAM2;signal transducing adaptor molecule (SH3 domain and ITAM motif) 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane;GO:0005730//nucleolus,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016197//endosomal transport;GO:0061024//membrane organization;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006886//intracellular protein transport,GO:0005515//protein binding,K04705//Jak-STAT signaling pathway;Endocytosis
1026,0,1,0,0,2,0,0,33,13,0,0,0,"CDKN1A;cyclin-dependent kinase inhibitor 1A (p21, Cip1)",GO:0005654//nucleoplasm;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070557//PCNA-p21 complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,"GO:0046685//response to arsenic-containing substance;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0030308//negative regulation of cell growth;GO:0048146//positive regulation of fibroblast proliferation;GO:0009411//response to UV;GO:0009636//response to toxic substance;GO:0071850//mitotic cell cycle arrest;GO:0007265//Ras protein signal transduction;GO:0071479//cellular response to ionizing radiation;GO:0010629//negative regulation of gene expression;GO:0045087//innate immune response;GO:0031668//cellular response to extracellular stimulus;GO:0051412//response to corticosterone;GO:0043068//positive regulation of programmed cell death;GO:0007050//cell cycle arrest;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0090400//stress-induced premature senescence;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0055093//response to hyperoxia;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0033158//regulation of protein import into nucleus, translocation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0090398//cellular senescence;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0031100//organ regeneration;GO:0042493//response to drug;GO:0006468//protein phosphorylation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:2000278//regulation of DNA biosynthetic process;GO:0042326//negative regulation of phosphorylation;GO:0010243//response to organonitrogen compound;GO:0045860//positive regulation of protein kinase activity;GO:0006974//cellular response to DNA damage stimulus",GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0030332//cyclin binding;GO:0031625//ubiquitin protein ligase binding;GO:0019912//cyclin-dependent protein kinase activating kinase activity,K06625//Prostate cancer;Transcriptional misregulation in cancer;HTLV-I infection;Pathways in cancer;Epstein-Barr virus infection;Cell cycle;Bladder cancer;Glioma;p53 signaling pathway;ErbB signaling pathway;Melanoma;Hepatitis C;Chronic myeloid leukemia
10260,0,1,0,42,60,54,16,0,111,0,0,0,DENND4A;DENN/MADD domain containing 4A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0032851//positive regulation of Rab GTPase activity;GO:0006355//regulation of transcription, DNA-templated",GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0003677//DNA binding,K12861//Spliceosome
10261,0,0,0,0,0,0,0,0,55,0,0,0,"IGSF6;immunoglobulin superfamily, member 6",GO:0005887//integral component of plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0006955//immune response,GO:0004888//transmembrane signaling receptor activity,-
10262,0,25,1,20,27,0,38,0,45,0,0,0,"SF3B4;splicing factor 3b, subunit 4, 49kDa",GO:0005681//spliceosomal complex;GO:0005689//U12-type spliceosomal complex;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K12831//Spliceosome
10263,0,32,1,0,0,43,45,71,11,0,0,0,CDK2AP2;cyclin-dependent kinase 2 associated protein 2,-,-,-,-
10265,0,0,0,0,18,0,29,0,15,0,0,0,IRX5;iroquois homeobox 5,GO:0005634//nucleus,"GO:0002027//regulation of heart rate;GO:0008406//gonad development;GO:0006351//transcription, DNA-templated;GO:0042551//neuron maturation;GO:0050896//response to stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0007601//visual perception;GO:0060040//retinal bipolar neuron differentiation;GO:0048701//embryonic cranial skeleton morphogenesis",GO:0005499//vitamin D binding;GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer
10266,0,0,0,5,0,0,0,0,0,0,0,0,RAMP2;receptor (G protein-coupled) activity modifying protein 2,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0043235//receptor complex;GO:0005905//coated pit;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome,GO:0070831//basement membrane assembly;GO:0007565//female pregnancy;GO:0045766//positive regulation of angiogenesis;GO:0002040//sprouting angiogenesis;GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0007507//heart development;GO:0006171//cAMP biosynthetic process;GO:0072659//protein localization to plasma membrane;GO:0034333//adherens junction assembly;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0043116//negative regulation of vascular permeability;GO:0030819//positive regulation of cAMP biosynthetic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0006816//calcium ion transport;GO:0015031//protein transport;GO:0032870//cellular response to hormone stimulus;GO:0006886//intracellular protein transport;GO:0070830//tight junction assembly;GO:2001214//positive regulation of vasculogenesis;GO:0097084//vascular smooth muscle cell development;GO:0032570//response to progesterone;GO:0031623//receptor internalization;GO:0032355//response to estradiol;GO:0001666//response to hypoxia;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0008217//regulation of blood pressure,GO:0015026//coreceptor activity;GO:0008565//protein transporter activity;GO:0005515//protein binding,K08448//Vascular smooth muscle contraction
10268,0,0,0,0,0,0,2,25,0,0,0,0,RAMP3;receptor (G protein-coupled) activity modifying protein 3,GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0009986//cell surface,"GO:0071392//cellular response to estradiol stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0001921//positive regulation of receptor recycling;GO:0072659//protein localization to plasma membrane;GO:0006816//calcium ion transport;GO:0015031//protein transport;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0086103//G-protein coupled receptor signaling pathway involved in heart process;GO:0031623//receptor internalization;GO:0006886//intracellular protein transport",GO:0008565//protein transporter activity;GO:0015026//coreceptor activity;GO:0004872//receptor activity;GO:0005515//protein binding,K08449//Vascular smooth muscle contraction
10269,0,27,0,0,12,0,0,19,22,0,47,0,ZMPSTE24;zinc metallopeptidase STE24,GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005637//nuclear inner membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0071586//CAAX-box protein processing;GO:0030327//prenylated protein catabolic process;GO:0006998//nuclear envelope organization,GO:0008235//metalloexopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,K06013//Terpenoid backbone biosynthesis
1027,0,1,0,0,16,0,0,0,15,67,1,0,"CDKN1B;cyclin-dependent kinase inhibitor 1B (p27, Kip1)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005768//endosome;GO:0005829//cytosol,"GO:0048102//autophagic cell death;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0033673//negative regulation of kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0048839//inner ear development;GO:0032355//response to estradiol;GO:0007050//cell cycle arrest;GO:0010942//positive regulation of cell death;GO:0071407//cellular response to organic cyclic compound;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0071285//cellular response to lithium ion;GO:0048015//phosphatidylinositol-mediated signaling;GO:0030308//negative regulation of cell growth;GO:0009749//response to glucose;GO:0031116//positive regulation of microtubule polymerization;GO:0045087//innate immune response;GO:0045930//negative regulation of mitotic cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0071850//mitotic cell cycle arrest;GO:0051271//negative regulation of cellular component movement;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001666//response to hypoxia;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0043200//response to amino acid;GO:0042326//negative regulation of phosphorylation;GO:0043434//response to peptide hormone;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0046686//response to cadmium ion;GO:0006813//potassium ion transport;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071236//cellular response to antibiotic;GO:0007605//sensory perception of sound;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042493//response to drug;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045732//positive regulation of protein catabolic process","GO:0032403//protein complex binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019903//protein phosphatase binding;GO:0051087//chaperone binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0030544//Hsp70 protein binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0005515//protein binding",K06624//Pathways in cancer;Small cell lung cancer;Prostate cancer;Transcriptional misregulation in cancer;Chronic myeloid leukemia;Epstein-Barr virus infection;Cell cycle;Measles;ErbB signaling pathway
10270,0,1,0,3,9,0,2,0,14,0,3,0,AKAP8;A kinase (PRKA) anchor protein 8,GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005730//nucleolus;GO:0001939//female pronucleus;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0000793//condensed chromosome;GO:0016020//membrane,GO:0007165//signal transduction;GO:0007067//mitotic nuclear division;GO:0007076//mitotic chromosome condensation,GO:0003690//double-stranded DNA binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,K15978//Epstein-Barr virus infection
10272,0,23,0,0,0,1,0,0,0,0,0,0,FSTL3;follistatin-like 3 (secreted glycoprotein),GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0044306//neuron projection terminus;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030514//negative regulation of BMP signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045671//negative regulation of osteoclast differentiation;GO:0030324//lung development;GO:0090101//negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0071248//cellular response to metal ion;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0022409//positive regulation of cell-cell adhesion;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0001503//ossification;GO:0002244//hematopoietic progenitor cell differentiation;GO:0001822//kidney development;GO:0006351//transcription, DNA-templated;GO:0030325//adrenal gland development",GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0048185//activin binding,K04661//TGF-beta signaling pathway
102723426,0,0,0,0,0,0,0,0,1,0,0,0,LOC102723426;uncharacterized LOC102723426,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K14443//RNA degradation
102723508,0,0,0,0,0,0,0,0,22,0,0,0,KANTR;KDM5C adjacent non-coding transcript,-,-,-,K05692//Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Phototransduction - fly;Adherens junction
102723631,0,0,0,0,0,0,0,2,19,0,0,0,LOC102723631;cancer/testis antigen family 45 member A-like,-,-,-,-
102723775,0,0,0,0,0,0,27,0,0,0,0,0,LINC01315;long intergenic non-protein coding RNA 1315,-,-,-,-
102724153,0,16,46,2,0,37,7,99,155,148,35,0,LOC102724153;uncharacterized LOC102724153,-,-,-,-
102724316,0,0,0,0,17,0,26,17,13,0,0,0,LOC102724316;uncharacterized LOC102724316,-,-,-,-
102724368,0,2,0,0,0,0,0,0,0,0,0,0,CELSR3-AS1;CELSR3 antisense RNA 1 (head to head),-,-,-,-
102724558,0,0,0,0,0,0,0,0,4,0,0,0,LOC102724558;uncharacterized LOC102724558,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
102724631,3,0,0,0,0,0,2,0,7,0,0,0,"LOC102724631;POTE ankyrin domain family, member B-like",-,-,-,-
102724814,53,949,475,636,1008,20,34,971,181,0,1135,2,LOC102724814;uncharacterized LOC102724814,-,-,-,K12391//Lysosome
102724855,87,0,0,0,0,0,0,0,21,0,0,0,CTD-2151A2.1;uncharacterized LOC102724855,-,-,-,K01195//Starch and sucrose metabolism;Drug metabolism - other enzymes;Lysosome;Porphyrin and chlorophyll metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Glycosaminoglycan degradation
10273,90,514,189,466,689,0,0,733,175,1,1127,3,"STUB1;STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0042405//nuclear inclusion body;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0031371//ubiquitin conjugating enzyme complex;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0000209//protein polyubiquitination;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0090035//positive regulation of chaperone-mediated protein complex assembly;GO:0031398//positive regulation of protein ubiquitination;GO:0006281//DNA repair;GO:0071218//cellular response to misfolded protein;GO:0070534//protein K63-linked ubiquitination;GO:0031943//regulation of glucocorticoid metabolic process;GO:0051604//protein maturation,"GO:0001664//G-protein coupled receptor binding;GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0051787//misfolded protein binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046332//SMAD binding;GO:0019899//enzyme binding;GO:0030911//TPR domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0030674//protein binding, bridging;GO:0051879//Hsp90 protein binding;GO:0030544//Hsp70 protein binding;GO:0016874//ligase activity;GO:0034450//ubiquitin-ubiquitin ligase activity",K09561//Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum
10274,0,0,0,15,34,21,32,0,20,0,0,0,STAG1;stromal antigen 1,"GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0005694//chromosome;GO:0030054//cell junction;GO:0005829//cytosol",GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle,GO:0005515//protein binding;GO:0003682//chromatin binding,K06671//Meiosis - yeast;Cell cycle;Cell cycle - yeast
10276,0,32,1,53,189,0,39,120,61,60,10,0,NET1;neuroepithelial cell transforming 1,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0007165//signal transduction;GO:0071479//cellular response to ionizing radiation;GO:0007264//small GTPase mediated signal transduction;GO:0001558//regulation of cell growth;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0070301//cellular response to hydrogen peroxide;GO:0051451//myoblast migration,GO:0017049//GTP-Rho binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K07532//Tuberculosis;Axon guidance;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12365//Chemokine signaling pathway;K12331//Vascular smooth muscle contraction
10277,0,47,0,20,177,0,2,1,86,5,0,0,UBE4B;ubiquitination factor E4B,GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0009411//response to UV,GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0019899//enzyme binding,K10597//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis
10278,0,1,1,1,10,0,0,60,0,46,7,0,EFS;embryonal Fyn-associated substrate,GO:0005737//cytoplasm,GO:0007155//cell adhesion;GO:0035556//intracellular signal transduction,GO:0017124//SH3 domain binding;GO:0019904//protein domain specific binding,K05726//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Leukocyte transendothelial migration;Focal adhesion
10279,110,0,0,0,0,0,14,0,15,0,0,0,"PRSS16;protease, serine, 16 (thymus)",GO:0005768//endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005764//lysosome,GO:0030163//protein catabolic process;GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity,-
1028,0,1,0,22,0,0,0,1,0,0,44,0,"CDKN1C;cyclin-dependent kinase inhibitor 1C (p57, Kip2)",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0033673//negative regulation of kinase activity;GO:0007568//aging;GO:0030099//myeloid cell differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0007050//cell cycle arrest;GO:0071514//genetic imprinting;GO:0042551//neuron maturation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001501//skeletal system development;GO:0042326//negative regulation of phosphorylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060065//uterus development;GO:0060669//embryonic placenta morphogenesis;GO:0001822//kidney development;GO:0043010//camera-type eye development;GO:0055123//digestive system development;GO:0035264//multicellular organism growth;GO:0030325//adrenal gland development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity,K09993//Cell cycle
10280,0,0,0,0,0,0,1,1,14,0,0,0,SIGMAR1;sigma non-opioid intracellular receptor 1,GO:0005637//nuclear inner membrane;GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005811//lipid particle;GO:0016021//integral component of membrane;GO:0030426//growth cone,GO:0006869//lipid transport;GO:0007399//nervous system development;GO:0043523//regulation of neuron apoptotic process;GO:0008219//cell death;GO:0038003//opioid receptor signaling pathway,GO:0008144//drug binding;GO:0004985//opioid receptor activity,-
10281,0,0,0,0,0,0,0,0,6,0,13,0,DSCR4;Down syndrome critical region gene 4,-,-,-,-
10282,0,0,0,26,87,0,5,0,0,0,0,0,BET1;Bet1 golgi vesicular membrane trafficking protein,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031985//Golgi cisterna,GO:0048280//vesicle fusion with Golgi apparatus;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0019905//syntaxin binding;GO:0005515//protein binding,K08504//SNARE interactions in vesicular transport
10284,0,31,1,28,48,0,0,0,1,0,0,0,"SAP18;Sin3A-associated protein, 18kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0061574//ASAP complex;GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0000118//histone deacetylase complex;GO:0016607//nuclear speck,"GO:0006351//transcription, DNA-templated;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0043065//positive regulation of apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0006397//mRNA processing",GO:0003714//transcription corepressor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14324//RNA transport;mRNA surveillance pathway
10285,0,0,0,5,0,7,0,0,16,0,0,0,SMNDC1;survival motor neuron domain containing 1,GO:0045111//intermediate filament cytoskeleton;GO:0005681//spliceosomal complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015030//Cajal body,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions;GO:0006915//apoptotic process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12839//Spliceosome
10286,0,13,0,14,30,0,0,0,0,0,14,0,BCAS2;breast carcinoma amplified sequence 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005681//spliceosomal complex,"GO:0000375//RNA splicing, via transesterification reactions;GO:0008380//RNA splicing;GO:0006397//mRNA processing",GO:0005515//protein binding,K12861//Spliceosome
10287,0,0,0,0,0,3,0,0,12,0,0,0,RGS19;regulator of G-protein signaling 19,GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005834//heterotrimeric G-protein complex;GO:0005903//brush border;GO:0005737//cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0006914//autophagy;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0001965//G-protein alpha-subunit binding;GO:0005096//GTPase activator activity,K07524//Axon guidance
10288,64,0,0,0,0,0,16,0,42,0,9,0,"LILRB2;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2",GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0006955//immune response;GO:0002578//negative regulation of antigen processing and presentation;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0007267//cell-cell signaling;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0006968//cellular defense response;GO:0002666//positive regulation of T cell tolerance induction;GO:0042130//negative regulation of T cell proliferation;GO:0034113//heterotypic cell-cell adhesion;GO:2001198//regulation of dendritic cell differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0051926//negative regulation of calcium ion transport;GO:0050776//regulation of immune response;GO:0042102//positive regulation of T cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0007165//signal transduction,GO:0023029//MHC class Ib protein binding;GO:0050839//cell adhesion molecule binding;GO:0008157//protein phosphatase 1 binding;GO:0005515//protein binding;GO:0032396//inhibitory MHC class I receptor activity;GO:0042288//MHC class I protein binding;GO:0004872//receptor activity,K06512//B cell receptor signaling pathway;Osteoclast differentiation
10289,0,0,1,15,38,0,0,0,4,0,0,0,EIF1B;eukaryotic translation initiation factor 1B,-,GO:0006446//regulation of translational initiation;GO:0006413//translational initiation,GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding,K03113//RNA transport
1029,0,0,0,0,0,0,0,0,9,0,6,0,CDKN2A;cyclin-dependent kinase inhibitor 2A,GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0035985//senescence-associated heterochromatin focus;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol,"GO:2000774//positive regulation of cellular senescence;GO:0048103//somatic stem cell division;GO:1902510//regulation of apoptotic DNA fragmentation;GO:0008637//apoptotic mitochondrial changes;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007050//cell cycle arrest;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0033235//positive regulation of protein sumoylation;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0071158//positive regulation of cell cycle arrest;GO:0000075//cell cycle checkpoint;GO:0007265//Ras protein signal transduction;GO:2000111//positive regulation of macrophage apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090399//replicative senescence;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0042326//negative regulation of phosphorylation;GO:0031648//protein destabilization;GO:0046825//regulation of protein export from nucleus;GO:0070534//protein K63-linked ubiquitination;GO:0000278//mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030889//negative regulation of B cell proliferation;GO:0001953//negative regulation of cell-matrix adhesion;GO:0035986//senescence-associated heterochromatin focus assembly;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0031647//regulation of protein stability;GO:0050821//protein stabilization;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090398//cellular senescence;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0006364//rRNA processing;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0006469//negative regulation of protein kinase activity",GO:0019901//protein kinase binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0051059//NF-kappaB binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008134//transcription factor binding;GO:0055105//ubiquitin-protein transferase inhibitor activity;GO:0097371//MDM2/MDM4 family protein binding,K06621//Bladder cancer;Glioma;p53 signaling pathway;Cell cycle;Non-small cell lung cancer;Chronic myeloid leukemia;Melanoma;Pathways in cancer;HTLV-I infection;Pancreatic cancer
10290,80,0,0,0,12,57,37,41,98,0,16,443,SPEG;SPEG complex locus,GO:0005634//nucleus,GO:0001701//in utero embryonic development;GO:0060541//respiratory system development;GO:0007517//muscle organ development;GO:0055013//cardiac muscle cell development;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell proliferation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
10291,0,51,0,33,191,20,1,0,25,23,6,0,"SF3A1;splicing factor 3a, subunit 1, 120kDa",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005684//U2-type spliceosomal complex,"GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000389//mRNA 3'-splice site recognition;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding,K12825//Spliceosome
10293,102,0,0,0,0,0,0,0,27,0,20,0,TRAIP;TRAF interacting protein,GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination;GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:0006915//apoptotic process,GO:0008270//zinc ion binding;GO:0005057//receptor signaling protein activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
10294,0,0,0,21,99,0,0,0,55,1,0,0,"DNAJA2;DnaJ (Hsp40) homolog, subfamily A, member 2",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0008284//positive regulation of cell proliferation;GO:0042026//protein refolding;GO:0009408//response to heat,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding;GO:0051087//chaperone binding;GO:0005524//ATP binding,K09503//Protein processing in endoplasmic reticulum
10295,0,0,0,4,42,0,0,44,12,0,0,0,BCKDK;branched chain ketoacid dehydrogenase kinase,GO:0005739//mitochondrion;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0009083//branched-chain amino acid catabolic process;GO:0016310//phosphorylation;GO:0009063//cellular amino acid catabolic process;GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0047323//[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity;GO:0005524//ATP binding;GO:0016301//kinase activity,-
10296,0,27,1,2,27,0,18,42,53,0,0,0,MAEA;macrophage erythroblast attacher,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005826//actomyosin contractile ring;GO:0005819//spindle;GO:0016363//nuclear matrix;GO:0005887//integral component of plasma membrane,GO:0051301//cell division;GO:0043249//erythrocyte maturation;GO:0007346//regulation of mitotic cell cycle;GO:0007049//cell cycle;GO:0048822//enucleate erythrocyte development;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0007010//cytoskeleton organization;GO:0007155//cell adhesion,GO:0003779//actin binding,-
10297,82,241,174,65,183,16,17,252,77,73,572,0,APC2;adenomatosis polyposis coli 2,GO:0016342//catenin complex;GO:0048471//perinuclear region of cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005884//actin filament;GO:0031258//lamellipodium membrane;GO:0005737//cytoplasm;GO:0005881//cytoplasmic microtubule;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane,GO:0016055//Wnt signaling pathway;GO:0035414//negative regulation of catenin import into nucleus;GO:0090090//negative regulation of canonical Wnt signaling pathway,GO:0008013//beta-catenin binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K02085//HTLV-I infection;Regulation of actin cytoskeleton;Wnt signaling pathway;Endometrial cancer;Pathways in cancer;Colorectal cancer;Basal cell carcinoma
10298,42,16,0,16,28,0,14,0,8,0,20,0,PAK4;p21 protein (Cdc42/Rac)-activated kinase 4,GO:0005794//Golgi apparatus;GO:0005925//focal adhesion,GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006928//cellular component movement;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0016477//cell migration;GO:0016049//cell growth;GO:0007165//signal transduction;GO:0007049//cell cycle,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding,K05734//ErbB signaling pathway;Focal adhesion;Renal cell carcinoma;Axon guidance;T cell receptor signaling pathway;Regulation of actin cytoskeleton
10299,45,1,0,0,6,16,0,0,47,0,0,0,"MARCH6;membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase",GO:0016020//membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0070936//protein K48-linked ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding;GO:0019899//enzyme binding;GO:0031624//ubiquitin conjugating enzyme binding,K10661//Protein processing in endoplasmic reticulum
103,0,183,1,73,359,26,1,0,48,56,7,0,"ADAR;adenosine deaminase, RNA-specific",GO:0005730//nucleolus;GO:0044530//supraspliceosomal complex;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0019221//cytokine-mediated signaling pathway;GO:0031054//pre-miRNA processing;GO:0045071//negative regulation of viral genome replication;GO:0006611//protein export from nucleus;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0016556//mRNA modification;GO:0006606//protein import into nucleus;GO:0051607//defense response to virus;GO:0006382//adenosine to inosine editing;GO:0060337//type I interferon signaling pathway;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0009615//response to virus;GO:0006397//mRNA processing;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0035455//response to interferon-alpha;GO:0045070//positive regulation of viral genome replication;GO:0016553//base conversion or substitution editing;GO:0045087//innate immune response;GO:0001701//in utero embryonic development,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity,K12968//Cytosolic DNA-sensing pathway;Influenza A;Measles
1030,0,0,0,2,0,16,21,0,44,0,0,0,"CDKN2B;cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)",GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0042326//negative regulation of phosphorylation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0034097//response to cytokine;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle;GO:0031668//cellular response to extracellular stimulus;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0007568//aging;GO:0031670//cellular response to nutrient;GO:0014070//response to organic cyclic compound;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007050//cell cycle arrest;GO:0050680//negative regulation of epithelial cell proliferation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0030219//megakaryocyte differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0007093//mitotic cell cycle checkpoint;GO:0030858//positive regulation of epithelial cell differentiation;GO:0048536//spleen development;GO:0001889//liver development;GO:0007179//transforming growth factor beta receptor signaling pathway",GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,K04685//Small cell lung cancer;TGF-beta signaling pathway;Cell cycle;Pathways in cancer;HTLV-I infection
10300,0,0,0,0,1,7,25,0,44,56,0,0,KATNB1;katanin p80 (WD repeat containing) subunit B 1,GO:0016020//membrane;GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030424//axon;GO:0030496//midbody;GO:0008352//katanin complex;GO:0000922//spindle pole;GO:0005874//microtubule;GO:0005634//nucleus,GO:0006605//protein targeting;GO:0007026//negative regulation of microtubule depolymerization;GO:0010942//positive regulation of cell death;GO:0051013//microtubule severing;GO:0006200//ATP catabolic process;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0010976//positive regulation of neuron projection development;GO:0031117//positive regulation of microtubule depolymerization,GO:0008568//microtubule-severing ATPase activity;GO:0046982//protein heterodimerization activity;GO:0045502//dynein binding;GO:0008017//microtubule binding,K01062//Metabolic pathways;Ether lipid metabolism;Biosynthesis of secondary metabolites
10302,0,425,303,367,509,0,0,86,27,1,510,0,"SNAPC5;small nuclear RNA activating complex, polypeptide 5, 19kDa",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter",GO:0003700//sequence-specific DNA binding transcription factor activity,-
10307,0,35,0,10,0,17,0,82,27,0,9,0,"APBB3;amyloid beta (A4) precursor protein-binding, family B, member 3",GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,-
10308,0,0,0,11,0,17,14,0,18,0,0,0,ZNF267;zinc finger protein 267,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1031,0,0,0,0,7,0,0,0,0,0,0,0,"CDKN2C;cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)",GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008285//negative regulation of cell proliferation;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0030308//negative regulation of cell growth;GO:0000278//mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0042326//negative regulation of phosphorylation;GO:0007050//cell cycle arrest;GO:0048709//oligodendrocyte differentiation;GO:0000082//G1/S transition of mitotic cell cycle,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity,K06622//HTLV-I infection;Transcriptional misregulation in cancer;Cell cycle
10311,1,0,16,0,60,9,0,0,2,0,34,0,DSCR3;Down syndrome critical region gene 3,GO:0005634//nucleus,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction
10312,96,0,0,0,0,34,41,0,8,0,0,1,"TCIRG1;T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3","GO:0005739//mitochondrion;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0016324//apical plasma membrane;GO:0005765//lysosomal membrane",GO:0015992//proton transport;GO:0006968//cellular defense response;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0008284//positive regulation of cell proliferation;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity,K02154//Tuberculosis;Synaptic vesicle cycle;Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Lysosome;Oxidative phosphorylation;Metabolic pathways
10313,0,0,0,8,25,0,0,39,6,0,0,0,RTN3;reticulon 3,GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane,GO:0071786//endoplasmic reticulum tubular network organization;GO:0016032//viral process;GO:0006915//apoptotic process;GO:0016192//vesicle-mediated transport;GO:0006950//response to stress,-,K00688//Starch and sucrose metabolism;Insulin signaling pathway
10314,0,57,3,23,80,25,30,0,88,0,14,0,LANCL1;LanC lantibiotic synthetase component C-like 1 (bacterial),GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process;GO:0007186//G-protein coupled receptor signaling pathway,GO:0043295//glutathione binding;GO:0004930//G-protein coupled receptor activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017124//SH3 domain binding,-
10316,0,0,0,0,0,0,0,0,34,0,8,0,NMUR1;neuromedin U receptor 1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006821//chloride transport;GO:0048016//inositol phosphate-mediated signaling;GO:0019722//calcium-mediated signaling;GO:0006939//smooth muscle contraction;GO:0007202//activation of phospholipase C activity;GO:0006816//calcium ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0001607//neuromedin U receptor activity,K05052//Neuroactive ligand-receptor interaction
10317,0,0,0,0,0,25,1,0,0,0,0,0,"B3GALT5;UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5",GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006486//protein glycosylation,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity",K03877//Glycosphingolipid biosynthesis - lacto and neolacto series;Glycosphingolipid biosynthesis - globo series;Metabolic pathways
103171574,0,0,0,0,0,0,0,74,0,2,0,0,LOC103171574;uncharacterized LOC103171574,-,-,-,-
10318,0,34,36,4,16,16,0,1,40,0,0,0,TNIP1;TNFAIP3 interacting protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005622//intracellular,GO:0045071//negative regulation of viral genome replication;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050729//positive regulation of inflammatory response;GO:0006412//translation;GO:0007159//leukocyte cell-cell adhesion;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0085032//modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0009101//glycoprotein biosynthetic process;GO:0006952//defense response,GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0051019//mitogen-activated protein kinase binding,K06669//Oocyte meiosis;Meiosis - yeast;Cell cycle;Cell cycle - yeast
10319,88,8,0,0,0,15,10,202,68,0,11,122,"LAMC3;laminin, gamma 3",GO:0005578//proteinaceous extracellular matrix;GO:0016020//membrane;GO:0005604//basement membrane;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0060041//retina development in camera-type eye;GO:0000904//cell morphogenesis involved in differentiation;GO:0007601//visual perception;GO:0014002//astrocyte development;GO:0007155//cell adhesion,GO:0005198//structural molecule activity,K06247//Pathways in cancer;Toxoplasmosis;ECM-receptor interaction;Focal adhesion;Small cell lung cancer;Amoebiasis
1032,0,0,0,0,14,0,0,0,0,0,0,0,"CDKN2D;cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)",GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0009411//response to UV;GO:0008285//negative regulation of cell proliferation;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030308//negative regulation of cell growth;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007605//sensory perception of sound;GO:0048102//autophagic cell death;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0042326//negative regulation of phosphorylation;GO:0000731//DNA synthesis involved in DNA repair;GO:0000278//mitotic cell cycle;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0032526//response to retinoic acid;GO:0033280//response to vitamin D;GO:0007050//cell cycle arrest,GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0005515//protein binding,K06623//Cell cycle
10320,10,0,0,0,0,77,18,0,53,0,14,0,IKZF1;IKAROS family zinc finger 1 (Ikaros),GO:0005721//pericentric heterochromatin;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007498//mesoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0045660//positive regulation of neutrophil differentiation;GO:0006351//transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0007049//cell cycle;GO:0048541//Peyer's patch development;GO:0048538//thymus development;GO:0048535//lymph node development;GO:0051138//positive regulation of NK T cell differentiation;GO:0016568//chromatin modification;GO:0040018//positive regulation of multicellular organism growth;GO:0060041//retina development in camera-type eye;GO:0030183//B cell differentiation;GO:0001779//natural killer cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10321,0,0,0,0,0,0,0,0,26,0,0,0,CRISP3;cysteine-rich secretory protein 3,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0042581//specific granule;GO:0005578//proteinaceous extracellular matrix,GO:0006952//defense response;GO:0045087//innate immune response,-,-
10322,0,1,0,0,0,0,4,108,0,0,0,0,SMYD5;SMYD family member 5,-,GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0046872//metal ion binding,-
10324,0,0,0,0,0,18,0,0,11,0,0,0,KLHL41;kelch-like family member 41,GO:0031143//pseudopodium;GO:0001726//ruffle;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0031430//M band;GO:0005856//cytoskeleton,GO:0030239//myofibril assembly;GO:0045661//regulation of myoblast differentiation;GO:0016567//protein ubiquitination;GO:2000291//regulation of myoblast proliferation;GO:0031275//regulation of lateral pseudopodium assembly;GO:2001014//regulation of skeletal muscle cell differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0006941//striated muscle contraction,GO:0005515//protein binding,-
10325,0,0,0,3,19,0,12,0,9,0,0,0,RRAGB;Ras-related GTP binding B,GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005765//lysosomal membrane,GO:0071230//cellular response to amino acid stimulus;GO:0034613//cellular protein localization;GO:0032008//positive regulation of TOR signaling,GO:0005525//GTP binding;GO:0005515//protein binding,-
10326,0,0,0,0,0,0,0,26,0,6,0,0,SIRPB1;signal-regulatory protein beta 1,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0045087//innate immune response;GO:0007166//cell surface receptor signaling pathway;GO:0007165//signal transduction,GO:0005515//protein binding,K06551//Osteoclast differentiation
10327,0,23,1,8,47,0,0,0,20,0,1,0,"AKR1A1;aldo-keto reductase family 1, member A1 (aldehyde reductase)",GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0042840//D-glucuronate catabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0046185//aldehyde catabolic process;GO:0019853//L-ascorbic acid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006006//glucose metabolic process,GO:0009055//electron carrier activity;GO:0047939//L-glucuronate reductase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity,K00002//Metabolic pathways;Tyrosine metabolism;Naphthalene degradation;Glycerolipid metabolism;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Caprolactam degradation
10328,0,0,0,4,22,0,0,0,53,0,0,0,EMC8;ER membrane protein complex subunit 8,GO:0005739//mitochondrion;GO:0016020//membrane;GO:0072546//ER membrane protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
10329,0,0,1,0,0,0,0,53,7,0,0,0,TMEM5;transmembrane protein 5,GO:0005887//integral component of plasma membrane,-,-,-
10330,0,0,0,34,11,0,29,0,0,0,0,0,CNPY2;canopy FGF signaling regulator 2,GO:0005887//integral component of plasma membrane;GO:0005783//endoplasmic reticulum,GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0010629//negative regulation of gene expression;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process,GO:0005515//protein binding,K01647//Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Citrate cycle (TCA cycle);ABC transporters;Pyruvate metabolism;Methane metabolism;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments
10331,0,0,0,0,0,18,37,0,17,0,2,0,"B3GNT3;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3",GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane,GO:0044267//cellular protein metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,"GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity;GO:0008378//galactosyltransferase activity",K07970//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
10332,83,0,0,0,0,0,0,0,3,230,0,0,"CLEC4M;C-type lectin domain family 4, member M",GO:0016020//membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0046968//peptide antigen transport;GO:0035556//intracellular signal transduction;GO:0075733//intracellular transport of virus;GO:0009988//cell-cell recognition;GO:0019048//modulation by virus of host morphology or physiology;GO:0019079//viral genome replication;GO:0006897//endocytosis;GO:0010468//regulation of gene expression;GO:0019882//antigen processing and presentation;GO:0019062//virion attachment to host cell;GO:0007159//leukocyte cell-cell adhesion;GO:0030193//regulation of blood coagulation;GO:0045087//innate immune response,GO:0046872//metal ion binding;GO:0042605//peptide antigen binding;GO:0005537//mannose binding;GO:0030246//carbohydrate binding;GO:0046790//virion binding;GO:0030369//ICAM-3 receptor activity;GO:0004872//receptor activity,K06563//Phagosome;Measles;Tuberculosis
10333,0,0,0,0,0,0,25,0,72,0,0,0,TLR6;toll-like receptor 6,GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0035355//Toll-like receptor 2-Toll-like receptor 6 protein complex;GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0034150//toll-like receptor 6 signaling pathway;GO:0006954//inflammatory response;GO:0042496//detection of diacyl bacterial lipopeptide;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0043507//positive regulation of JUN kinase activity;GO:0050707//regulation of cytokine secretion;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042088//T-helper 1 type immune response;GO:0045087//innate immune response;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0042742//defense response to bacterium;GO:0002282//microglial cell activation involved in immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0046209//nitric oxide metabolic process;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0006955//immune response,GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0042498//diacyl lipopeptide binding;GO:0046982//protein heterodimerization activity;GO:0071723//lipopeptide binding,K10169//Phagosome;Chagas disease (American trypanosomiasis);Toll-like receptor signaling pathway;Tuberculosis
103344718,0,0,0,0,0,12,31,0,29,0,0,299,HOTS;H19 Opposite Tumor Suppressor,-,-,-,-
10335,41,56,68,12,17,15,1,102,54,30,2,363,MRVI1;murine retrovirus integration site 1 homolog,GO:0005789//endoplasmic reticulum membrane;GO:0031095//platelet dense tubular network membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0016529//sarcoplasmic reticulum,GO:0060087//relaxation of vascular smooth muscle;GO:0007596//blood coagulation;GO:0019934//cGMP-mediated signaling,GO:0005515//protein binding,K12337//Vascular smooth muscle contraction
103352539,70,10,0,0,0,59,1,0,80,0,5,1,LINC01410;long intergenic non-protein coding RNA 1410,-,-,-,-
10336,0,63,20,101,147,0,11,70,65,1,135,0,PCGF3;polycomb group ring finger 3,GO:0031519//PcG protein complex;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0008270//zinc ion binding,-
10342,0,48,0,45,118,22,35,0,28,2,0,0,TFG;TRK-fused gene,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction;GO:0008219//cell death,GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0042802//identical protein binding,K09292//Thyroid cancer;Pathways in cancer
10343,84,0,0,10,0,14,19,0,69,0,10,0,PKDREJ;polycystin (PKD) family receptor for egg jelly,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0050982//detection of mechanical stimulus;GO:0007340//acrosome reaction;GO:0070588//calcium ion transmembrane transport;GO:0060046//regulation of acrosome reaction;GO:0007218//neuropeptide signaling pathway,GO:0005262//calcium channel activity;GO:0005509//calcium ion binding,-
10344,0,0,0,0,0,0,0,0,15,0,1,0,CCL26;chemokine (C-C motif) ligand 26,GO:0005615//extracellular space,GO:0032855//positive regulation of Rac GTPase activity;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0030335//positive regulation of cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006954//inflammatory response;GO:0030838//positive regulation of actin filament polymerization;GO:0007267//cell-cell signaling;GO:0060326//cell chemotaxis;GO:0007165//signal transduction,GO:0008009//chemokine activity,K05514//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
10345,0,0,0,0,0,47,30,0,122,7,0,0,TRDN;triadin,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0033018//sarcoplasmic reticulum lumen;GO:0005737//cytoplasm;GO:0030314//junctional membrane complex;GO:0016529//sarcoplasmic reticulum;GO:0005891//voltage-gated calcium channel complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0034704//calcium channel complex,GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0006874//cellular calcium ion homeostasis;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0055085//transmembrane transport;GO:0031122//cytoplasmic microtubule organization;GO:0010649//regulation of cell communication by electrical coupling;GO:0060047//heart contraction;GO:0014070//response to organic cyclic compound;GO:1901846//positive regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0014902//myotube differentiation;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0090158//endoplasmic reticulum membrane organization;GO:0034220//ion transmembrane transport;GO:0006936//muscle contraction,"GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0030674//protein binding, bridging;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding",-
10346,4,0,0,0,29,0,0,0,40,0,0,0,TRIM22;tripartite motif containing 22,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015030//Cajal body,"GO:0016567//protein ubiquitination;GO:0009615//response to virus;GO:0006955//immune response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016032//viral process;GO:0070206//protein trimerization;GO:0051607//defense response to virus",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
10347,0,0,0,0,0,0,0,46,29,0,36,285,"ABCA7;ATP-binding cassette, sub-family A (ABC1), member 7",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0001891//phagocytic cup;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0010008//endosome membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0032587//ruffle membrane,GO:1901076//positive regulation of engulfment of apoptotic cell;GO:0055085//transmembrane transport;GO:1902430//negative regulation of beta-amyloid formation;GO:0032780//negative regulation of ATPase activity;GO:0033344//cholesterol efflux;GO:0018149//peptide cross-linking;GO:1902995//positive regulation of phospholipid efflux;GO:0017121//phospholipid scrambling;GO:0032781//positive regulation of ATPase activity;GO:0033700//phospholipid efflux;GO:0034504//protein localization to nucleus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0050766//positive regulation of phagocytosis;GO:1900223//positive regulation of beta-amyloid clearance;GO:0007613//memory;GO:0034380//high-density lipoprotein particle assembly;GO:0006200//ATP catabolic process;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0010875//positive regulation of cholesterol efflux;GO:0006909//phagocytosis,GO:0016887//ATPase activity;GO:0034188//apolipoprotein A-I receptor activity;GO:0005524//ATP binding;GO:0005215//transporter activity;GO:0005548//phospholipid transporter activity,K05645//ABC transporters
10349,0,0,20,0,0,13,0,0,105,0,18,0,"ABCA10;ATP-binding cassette, sub-family A (ABC1), member 10",GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process;GO:0006810//transport,GO:0016887//ATPase activity;GO:0005524//ATP binding,K05652//ABC transporters
10350,76,0,0,0,0,33,6,0,32,126,9,0,"ABCA9;ATP-binding cassette, sub-family A (ABC1), member 9",GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006200//ATP catabolic process;GO:0006810//transport,GO:0016887//ATPase activity;GO:0005524//ATP binding,K05651//ABC transporters
10351,1,0,0,0,0,43,10,46,36,0,0,0,"ABCA8;ATP-binding cassette, sub-family A (ABC1), member 8",GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0006810//transport,"GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05650//ABC transporters
10352,0,0,0,0,28,0,0,0,37,83,0,0,"WARS2;tryptophanyl tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0001570//vasculogenesis;GO:0006418//tRNA aminoacylation for protein translation;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0010467//gene expression,GO:0005524//ATP binding;GO:0004830//tryptophan-tRNA ligase activity,K01867//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;Aminoacyl-tRNA biosynthesis
1036,0,0,0,0,5,0,7,0,0,195,11,0,CDO1;cysteine dioxygenase type 1,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0000098//sulfur amino acid catabolic process;GO:0045471//response to ethanol;GO:0000097//sulfur amino acid biosynthetic process;GO:0042412//taurine biosynthetic process;GO:0006534//cysteine metabolic process;GO:0033762//response to glucagon;GO:0051591//response to cAMP;GO:0006954//inflammatory response;GO:0007595//lactation;GO:0019448//L-cysteine catabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0055114//oxidation-reduction process;GO:0043200//response to amino acid,GO:0017172//cysteine dioxygenase activity;GO:0008198//ferrous iron binding,K00456//Taurine and hypotaurine metabolism;Cysteine and methionine metabolism;Metabolic pathways
10360,0,11,0,0,17,0,0,37,17,0,9,0,NPM3;nucleophosmin/nucleoplasmin 3,GO:0005730//nucleolus,GO:0006364//rRNA processing;GO:0009303//rRNA transcription,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
10361,0,0,0,0,6,0,0,2,0,0,0,0,NPM2;nucleophosmin/nucleoplasmin 2,GO:0000789//cytoplasmic chromatin;GO:0005634//nucleus;GO:0000790//nuclear chromatin,GO:0007338//single fertilization;GO:0009790//embryo development;GO:0051260//protein homooligomerization;GO:0007096//regulation of exit from mitosis;GO:0045836//positive regulation of meiosis;GO:0009994//oocyte differentiation;GO:0045740//positive regulation of DNA replication;GO:0006338//chromatin remodeling;GO:0043085//positive regulation of catalytic activity,GO:0042393//histone binding;GO:0003676//nucleic acid binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding,-
10362,0,19,0,27,97,6,0,2,26,1,0,321,HMG20B;high mobility group 20B,GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0045666//positive regulation of neuron differentiation;GO:0007049//cell cycle;GO:0016568//chromatin modification;GO:0033234//negative regulation of protein sumoylation;GO:0006355//regulation of transcription, DNA-templated;GO:0035914//skeletal muscle cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007596//blood coagulation",GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
10363,0,0,0,0,3,44,0,1,35,0,0,0,HMG20A;high mobility group 20A,GO:0005634//nucleus,"GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,K10802//Base excision repair
10367,0,2,0,9,18,26,0,50,0,0,0,0,MICU1;mitochondrial calcium uptake 1,GO:0032592//integral component of mitochondrial membrane;GO:0034704//calcium channel complex;GO:1990246//uniplex complex;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005622//intracellular,GO:0006851//mitochondrial calcium ion transport;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0006952//defense response;GO:0051260//protein homooligomerization;GO:0070509//calcium ion import;GO:0051560//mitochondrial calcium ion homeostasis,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,-
10368,0,0,0,0,0,28,0,0,25,0,17,0,"CACNG3;calcium channel, voltage-dependent, gamma subunit 3",GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0005891//voltage-gated calcium channel complex,GO:0007268//synaptic transmission;GO:0006816//calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,GO:0005245//voltage-gated calcium channel activity,K04868//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Cardiac muscle contraction;Dilated cardiomyopathy
10369,61,0,0,0,0,0,0,13,25,0,9,0,"CACNG2;calcium channel, voltage-dependent, gamma subunit 2",GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0007528//neuromuscular junction development;GO:0051899//membrane depolarization;GO:0060081//membrane hyperpolarization;GO:0070588//calcium ion transmembrane transport;GO:0007268//synaptic transmission;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0006810//transport;GO:0019226//transmission of nerve impulse,GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0035255//ionotropic glutamate receptor binding,K04867//Dilated cardiomyopathy;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
10370,0,0,0,14,22,0,12,0,22,105,1,0,"CITED2;Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2",GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,"GO:0008283//cell proliferation;GO:0021602//cranial nerve morphogenesis;GO:0006351//transcription, DNA-templated;GO:0035802//adrenal cortex formation;GO:0030851//granulocyte differentiation;GO:0030336//negative regulation of cell migration;GO:0003197//endocardial cushion development;GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0003156//regulation of organ formation;GO:0010628//positive regulation of gene expression;GO:0035914//skeletal muscle cell differentiation;GO:0010629//negative regulation of gene expression;GO:0007507//heart development;GO:0048536//spleen development;GO:0001889//liver development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002089//lens morphogenesis in camera-type eye;GO:0060136//embryonic process involved in female pregnancy;GO:0060349//bone morphogenesis;GO:0070986//left/right axis specification;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0008584//male gonad development;GO:0022409//positive regulation of cell-cell adhesion;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0061156//pulmonary artery morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0045787//positive regulation of cell cycle;GO:0007530//sex determination;GO:0001843//neural tube closure;GO:0048596//embryonic camera-type eye morphogenesis;GO:0001892//embryonic placenta development;GO:0007368//determination of left/right symmetry;GO:0001947//heart looping;GO:0007422//peripheral nervous system development;GO:0034405//response to fluid shear stress;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060971//embryonic heart tube left/right pattern formation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0001570//vasculogenesis;GO:0061308//cardiac neural crest cell development involved in heart development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0048821//erythrocyte development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007569//cell aging;GO:0001666//response to hypoxia;GO:0009612//response to mechanical stimulus;GO:2001141//regulation of RNA biosynthetic process;GO:0046697//decidualization;GO:0043627//response to estrogen;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001829//trophectodermal cell differentiation;GO:2000020//positive regulation of male gonad development",GO:0001105//RNA polymerase II transcription coactivator activity;GO:0035035//histone acetyltransferase binding;GO:0046332//SMAD binding;GO:0050693//LBD domain binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0001102//RNA polymerase II activating transcription factor binding,-
10371,82,0,0,0,14,0,0,35,17,0,0,0,"SEMA3A;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A",GO:0005576//extracellular region;GO:0030424//axon;GO:0030425//dendrite;GO:0016020//membrane,GO:0010633//negative regulation of epithelial cell migration;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0048813//dendrite morphogenesis;GO:2001224//positive regulation of neuron migration;GO:0071526//semaphorin-plexin signaling pathway;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0007411//axon guidance;GO:0007413//axonal fasciculation;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0048485//sympathetic nervous system development;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:0097491//sympathetic neuron projection guidance;GO:0048880//sensory system development;GO:0061549//sympathetic ganglion development;GO:0050919//negative chemotaxis;GO:0001764//neuron migration;GO:0006915//apoptotic process;GO:0021675//nerve development;GO:0021772//olfactory bulb development;GO:0021612//facial nerve structural organization;GO:0097490//sympathetic neuron projection extension;GO:0048846//axon extension involved in axon guidance;GO:0002027//regulation of heart rate;GO:0060385//axonogenesis involved in innervation;GO:2000020//positive regulation of male gonad development;GO:0048841//regulation of axon extension involved in axon guidance;GO:0021785//branchiomotor neuron axon guidance,GO:0038191//neuropilin binding;GO:0004872//receptor activity;GO:0045499//chemorepellent activity;GO:0030215//semaphorin receptor binding,K06840//Axon guidance
10376,0,1,0,3,36,0,41,0,21,0,0,0,"TUBA1B;tubulin, alpha 1b",GO:0005881//cytoplasmic microtubule;GO:0070062//extracellular vesicular exosome;GO:0005874//microtubule,GO:0071353//cellular response to interleukin-4;GO:0051084//'de novo' posttranslational protein folding;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0000226//microtubule cytoskeleton organization;GO:0007017//microtubule-based process;GO:0044267//cellular protein metabolic process;GO:0006184//GTP catabolic process;GO:0006457//protein folding;GO:0051258//protein polymerization,GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07374//Gap junction;Phagosome;Pathogenic Escherichia coli infection
10379,0,32,1,11,15,0,0,0,0,0,0,0,IRF9;interferon regulatory factor 9,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0060337//type I interferon signaling pathway;GO:0045351//type I interferon biosynthetic process;GO:0051607//defense response to virus;GO:0006355//regulation of transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway",GO:0000975//regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K04693//Influenza A;Measles;Hepatitis C;Jak-STAT signaling pathway;Herpes simplex infection;Osteoclast differentiation
1038,60,0,0,23,117,0,0,0,0,0,0,0,"CDR1;cerebellar degeneration-related protein 1, 34kDa",-,-,-,K05730//Regulation of actin cytoskeleton;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Focal adhesion;Fc epsilon RI signaling pathway;Chemokine signaling pathway;Leukocyte transendothelial migration;B cell receptor signaling pathway;Fc gamma R-mediated phagocytosis
10380,0,0,0,0,12,11,0,0,11,0,0,0,"BPNT1;3'(2'), 5'-bisphosphate nucleotidase 1",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006139//nucleobase-containing compound metabolic process;GO:0016311//dephosphorylation;GO:0007399//nervous system development;GO:0006805//xenobiotic metabolic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0044281//small molecule metabolic process,"GO:0000287//magnesium ion binding;GO:0004441//inositol-1,4-bisphosphate 1-phosphatase activity;GO:0008441//3'(2'),5'-bisphosphate nucleotidase activity",K01082//Sulfur metabolism;Metabolic pathways;Microbial metabolism in diverse environments
10381,0,0,0,0,0,0,0,0,0,0,11,0,"TUBB3;tubulin, beta 3 class III",GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0051084//'de novo' posttranslational protein folding;GO:0006184//GTP catabolic process;GO:0006457//protein folding;GO:0051258//protein polymerization;GO:0007411//axon guidance;GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome
10382,5,0,0,0,0,12,2,0,0,0,0,0,"TUBB4A;tubulin, beta 4A class IVa",GO:0005634//nucleus;GO:0033269//internode region of axon;GO:0005874//microtubule;GO:0005929//cilium;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0070062//extracellular vesicular exosome,GO:0051084//'de novo' posttranslational protein folding;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006457//protein folding;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005200//structural constituent of cytoskeleton,K07375//Pathogenic Escherichia coli infection;Phagosome;Gap junction
10383,0,62,0,7,93,0,0,0,0,0,0,0,"TUBB4B;tubulin, beta 4B class IVb",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0031982//vesicle;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005874//microtubule,GO:0051084//'de novo' posttranslational protein folding;GO:0042267//natural killer cell mediated cytotoxicity;GO:0006457//protein folding;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process;GO:0006928//cellular component movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0051082//unfolded protein binding;GO:0003725//double-stranded RNA binding;GO:0005200//structural constituent of cytoskeleton;GO:0042288//MHC class I protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome
10384,0,0,0,0,0,11,0,0,9,0,0,0,"BTN3A3;butyrophilin, subfamily 3, member A3",GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0002456//T cell mediated immunity,-,-
10385,0,0,0,0,0,0,0,0,34,54,0,0,"BTN2A2;butyrophilin, subfamily 2, member A2",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0031324//negative regulation of cellular metabolic process;GO:0050710//negative regulation of cytokine secretion;GO:0046007//negative regulation of activated T cell proliferation,-,-
10388,0,0,0,0,18,13,5,0,22,0,12,0,SYCP2;synaptonemal complex protein 2,GO:0000800//lateral element;GO:0000795//synaptonemal complex;GO:0005634//nucleus,GO:0007130//synaptonemal complex assembly;GO:0007143//female meiotic division;GO:0009566//fertilization;GO:0007140//male meiosis;GO:0043066//negative regulation of apoptotic process;GO:0048808//male genitalia morphogenesis,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K09880//Cysteine and methionine metabolism
10389,41,0,0,0,0,0,10,0,39,0,0,0,SCML2;sex comb on midleg-like 2 (Drosophila),GO:0005634//nucleus;GO:0031519//PcG protein complex,"GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
1039,0,0,0,12,18,0,38,7,22,0,0,0,"CDR2;cerebellar degeneration-related protein 2, 62kDa",GO:0005737//cytoplasm,-,GO:0005515//protein binding,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
10390,0,33,0,30,91,0,17,0,18,0,77,0,CEPT1;choline/ethanolamine phosphotransferase 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006629//lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0044281//small molecule metabolic process;GO:0006656//phosphatidylcholine biosynthetic process,GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0046872//metal ion binding;GO:0004307//ethanolaminephosphotransferase activity,K13644//Metabolic pathways;Ether lipid metabolism;Glycerophospholipid metabolism
10391,84,0,0,0,0,14,36,0,47,1,3,0,"CORO2B;coronin, actin binding protein, 2B",GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0016020//membrane,GO:0030036//actin cytoskeleton organization,GO:0003779//actin binding;GO:0051015//actin filament binding,K13882//Phagosome;Tuberculosis
103910,127,155,1,108,135,0,1,0,0,0,0,0,"MYL12B;myosin, light chain 12B, regulatory",GO:0030018//Z disc;GO:0045177//apical part of cell;GO:0016460//myosin II complex;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006936//muscle contraction;GO:0008360//regulation of cell shape;GO:0007411//axon guidance,GO:0005515//protein binding;GO:0005509//calcium ion binding,K12757//Tight junction;Regulation of actin cytoskeleton;Focal adhesion;Leukocyte transendothelial migration
10392,0,0,0,0,14,0,0,0,48,11,0,0,NOD1;nucleotide-binding oligomerization domain containing 1,GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,"GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000187//activation of MAPK activity;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0009595//detection of biotic stimulus;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035556//intracellular signal transduction;GO:0046330//positive regulation of JNK cascade;GO:0042742//defense response to bacterium;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0006952//defense response;GO:0042228//interleukin-8 biosynthetic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0016045//detection of bacterium;GO:0007254//JNK cascade",GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005524//ATP binding;GO:0042834//peptidoglycan binding;GO:0050700//CARD domain binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K08727//NOD-like receptor signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Shigellosis;Pertussis
10393,0,59,10,97,128,0,13,0,29,0,131,0,ANAPC10;anaphase promoting complex subunit 10,GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex,GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division,-,K03357//Cell cycle;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Oocyte meiosis;HTLV-I infection;Meiosis - yeast
10394,0,0,14,0,0,17,25,0,0,0,0,0,PRG3;proteoglycan 3,-,GO:0045575//basophil activation;GO:0001694//histamine biosynthetic process;GO:0042554//superoxide anion generation;GO:0006955//immune response;GO:0042119//neutrophil activation;GO:0019370//leukotriene biosynthetic process;GO:0017148//negative regulation of translation;GO:0045416//positive regulation of interleukin-8 biosynthetic process,GO:0030246//carbohydrate binding,K10786//Asthma
10395,159,0,0,0,0,67,60,0,87,0,0,12,DLC1;DLC1 Rho GTPase activating protein,GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005901//caveola,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0030336//negative regulation of cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0030900//forebrain development;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0035024//negative regulation of Rho protein signal transduction;GO:0035307//positive regulation of protein dephosphorylation;GO:0021575//hindbrain morphogenesis;GO:0003007//heart morphogenesis;GO:1900119//positive regulation of execution phase of apoptosis;GO:0001843//neural tube closure;GO:0048041//focal adhesion assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0032321//positive regulation of Rho GTPase activity;GO:0006915//apoptotic process,GO:0030675//Rac GTPase activator activity;GO:0005100//Rho GTPase activator activity;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0042169//SH2 domain binding,K08773//Pancreatic cancer;Pathways in cancer;K12490//Endocytosis;K07526//Axon guidance
10396,96,1,1,15,24,13,0,0,17,12,8,0,"ATP8A1;ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1",GO:0042584//chromaffin granule membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:0055085//transmembrane transport;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,-
10397,0,585,21,529,1837,21,11,4,15,0,12,0,NDRG1;N-myc downstream regulated 1,GO:0005913//cell-cell adherens junction;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0055038//recycling endosome membrane,"GO:0045576//mast cell activation;GO:0008219//cell death;GO:0090232//positive regulation of spindle checkpoint;GO:0010038//response to metal ion;GO:0032287//peripheral nervous system myelin maintenance;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0071456//cellular response to hypoxia",GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0017137//Rab GTPase binding;GO:0043015//gamma-tubulin binding,-
10398,0,0,0,0,17,0,0,0,43,0,0,0,"MYL9;myosin, light chain 9, regulatory",GO:0005829//cytosol;GO:0030018//Z disc;GO:0001725//stress fiber;GO:0005859//muscle myosin complex,GO:0006936//muscle contraction;GO:0070527//platelet aggregation;GO:0007411//axon guidance;GO:0006937//regulation of muscle contraction,GO:0008307//structural constituent of muscle;GO:0005509//calcium ion binding,K12757//Focal adhesion;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Tight junction;K12755//Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Focal adhesion
10399,0,270,1,107,590,0,0,0,0,0,0,0,"GNB2L1;guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0015935//small ribosomal subunit;GO:0043204//perikaryon;GO:0030496//midbody;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005856//cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0001891//phagocytic cup,GO:0051302//regulation of cell division;GO:0051898//negative regulation of protein kinase B signaling;GO:0048511//rhythmic process;GO:0016032//viral process;GO:0007369//gastrulation;GO:2000543//positive regulation of gastrulation;GO:0017148//negative regulation of translation;GO:0030178//negative regulation of Wnt signaling pathway;GO:2000114//regulation of establishment of cell polarity;GO:0043065//positive regulation of apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0051901//positive regulation of mitochondrial depolarization;GO:0010629//negative regulation of gene expression;GO:0032880//regulation of protein localization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0032464//positive regulation of protein homooligomerization;GO:0030822//positive regulation of cAMP catabolic process;GO:0090003//regulation of establishment of protein localization to plasma membrane;GO:0050765//negative regulation of phagocytosis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0030335//positive regulation of cell migration;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0030308//negative regulation of cell growth;GO:0051726//regulation of cell cycle,GO:0005102//receptor binding;GO:0032947//protein complex scaffold;GO:0042169//SH2 domain binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0008200//ion channel inhibitor activity;GO:0019899//enzyme binding;GO:0030971//receptor tyrosine kinase binding;GO:0019903//protein phosphatase binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005080//protein kinase C binding,K14753//Measles
104,75,0,0,14,31,0,4,19,49,0,0,0,"ADARB1;adenosine deaminase, RNA-specific, B1",GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0030336//negative regulation of cell migration;GO:0051726//regulation of cell cycle;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0006397//mRNA processing;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0006382//adenosine to inosine editing;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0006396//RNA processing;GO:0016553//base conversion or substitution editing;GO:0045070//positive regulation of viral genome replication;GO:0016556//mRNA modification,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004000//adenosine deaminase activity;GO:0003729//mRNA binding;GO:0003725//double-stranded RNA binding;GO:0003723//RNA binding;GO:0003726//double-stranded RNA adenosine deaminase activity,-
1040,0,0,0,0,46,9,0,115,18,0,0,0,CDS1;CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006657//CDP-choline pathway;GO:0007602//phototransduction;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0004605//phosphatidate cytidylyltransferase activity,K00981//Glycerophospholipid metabolism;Ribosome;Shigellosis;Phosphatidylinositol signaling system;Metabolic pathways;RNA degradation
10400,0,0,0,0,12,10,0,0,0,0,11,0,PEMT;phosphatidylethanolamine N-methyltransferase,GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,GO:0008283//cell proliferation;GO:0006629//lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0032259//methylation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0044281//small molecule metabolic process,GO:0004608//phosphatidylethanolamine N-methyltransferase activity;GO:0080101//phosphatidyl-N-dimethylethanolamine N-methyltransferase activity;GO:0000773//phosphatidyl-N-methylethanolamine N-methyltransferase activity,K00551//Glycerophospholipid metabolism;Metabolic pathways
10401,3,36,1,7,35,6,0,0,9,0,0,516,"PIAS3;protein inhibitor of activated STAT, 3",GO:0030425//dendrite;GO:0045202//synapse;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0006355//regulation of transcription, DNA-templated;GO:0045838//positive regulation of membrane potential;GO:0033235//positive regulation of protein sumoylation;GO:0010628//positive regulation of gene expression;GO:0009725//response to hormone",GO:0019899//enzyme binding;GO:0047485//protein N-terminus binding;GO:0019789//SUMO ligase activity;GO:0015459//potassium channel regulator activity;GO:0003676//nucleic acid binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K16064//Ubiquitin mediated proteolysis;Jak-STAT signaling pathway
10402,0,51,0,0,0,0,0,0,4,0,19,0,"ST3GAL6;ST3 beta-galactoside alpha-2,3-sialyltransferase 6",GO:0070062//extracellular vesicular exosome;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0097503//sialylation;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006664//glycolipid metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0071354//cellular response to interleukin-6,"GO:0052798//beta-galactoside alpha-2,3-sialyltransferase activity",K03792//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
10403,0,0,45,0,0,35,27,0,52,0,0,0,NDC80;NDC80 kinetochore complex component,"GO:0005829//cytosol;GO:0031262//Ndc80 complex;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0000942//condensed nuclear chromosome outer kinetochore",GO:0000070//mitotic sister chromatid segregation;GO:0000132//establishment of mitotic spindle orientation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007052//mitotic spindle organization;GO:0007059//chromosome segregation,GO:0005515//protein binding,-
10404,0,18,0,1,0,0,19,0,0,0,0,0,CPQ;carboxypeptidase Q,GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0006590//thyroid hormone generation;GO:0006508//proteolysis;GO:0042246//tissue regeneration;GO:0043171//peptide catabolic process,GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0070573//metallodipeptidase activity;GO:0004180//carboxypeptidase activity,K14592//Vitamin digestion and absorption;K06503//Phagosome;Hematopoietic cell lineage;Endocytosis
10407,0,0,0,0,0,0,2,0,0,0,0,0,SPAG11B;sperm associated antigen 11B,GO:0005576//extracellular region,GO:0007283//spermatogenesis,-,-
10409,0,140,43,69,229,0,31,58,83,85,149,1,"BASP1;brain abundant, membrane attached signal protein 1",GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0008180//COP9 signalosome,"GO:0021762//substantia nigra development;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0072075//metanephric mesenchyme development;GO:2001076//positive regulation of metanephric ureteric bud development;GO:0060421//positive regulation of heart growth;GO:0060539//diaphragm development;GO:0008406//gonad development;GO:0007356//thorax and anterior abdomen determination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060231//mesenchymal to epithelial transition",GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0044212//transcription regulatory region DNA binding;GO:0003714//transcription corepressor activity,-
1041,62,0,0,0,0,0,0,0,16,0,16,0,CDSN;corneodesmosin,GO:0001533//cornified envelope;GO:0005911//cell-cell junction;GO:0030057//desmosome;GO:0070062//extracellular vesicular exosome,GO:0016337//single organismal cell-cell adhesion;GO:0007155//cell adhesion;GO:0030216//keratinocyte differentiation;GO:0008544//epidermis development;GO:0043589//skin morphogenesis,GO:0042803//protein homodimerization activity,-
10410,0,0,0,0,38,15,2,0,0,0,0,0,IFITM3;interferon induced transmembrane protein 3,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031902//late endosome membrane;GO:0005765//lysosomal membrane,GO:0006955//immune response;GO:0045071//negative regulation of viral genome replication;GO:0046597//negative regulation of viral entry into host cell;GO:0034341//response to interferon-gamma;GO:0032897//negative regulation of viral transcription;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0035456//response to interferon-beta;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0035455//response to interferon-alpha,GO:0005515//protein binding,K06566//B cell receptor signaling pathway
10411,0,44,48,23,11,32,8,0,48,0,5,0,RAPGEF3;Rap guanine nucleotide exchange factor (GEF) 3,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005952//cAMP-dependent protein kinase complex,GO:0007596//blood coagulation;GO:0071320//cellular response to cAMP;GO:0006112//energy reserve metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0030168//platelet activation;GO:0032486//Rap protein signal transduction;GO:0045859//regulation of protein kinase activity;GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:0050796//regulation of insulin secretion;GO:0019933//cAMP-mediated signaling;GO:0032854//positive regulation of Rap GTPase activity;GO:0061028//establishment of endothelial barrier;GO:0045766//positive regulation of angiogenesis;GO:0001525//angiogenesis;GO:0030822//positive regulation of cAMP catabolic process;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0044281//small molecule metabolic process,GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0030552//cAMP binding;GO:0005515//protein binding;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K08014//Serotonergic synapse;Leukocyte transendothelial migration;Long-term potentiation
10412,0,164,47,168,184,0,17,0,0,0,65,0,NSA2;NSA2 ribosome biogenesis homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
10413,0,22,2,65,104,6,0,0,21,0,13,0,YAP1;Yes-associated protein 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006974//cellular response to DNA damage stimulus;GO:0060242//contact inhibition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048368//lateral mesoderm development;GO:0035019//somatic stem cell maintenance;GO:0030857//negative regulation of epithelial cell differentiation;GO:0030216//keratinocyte differentiation;GO:0071480//cellular response to gamma radiation;GO:0035329//hippo signaling;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0001570//vasculogenesis;GO:0010837//regulation of keratinocyte proliferation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0030903//notochord development;GO:0072091//regulation of stem cell proliferation;GO:0008283//cell proliferation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0003143//embryonic heart tube morphogenesis;GO:0046622//positive regulation of organ growth;GO:0010467//gene expression;GO:0048339//paraxial mesoderm development,GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0044212//transcription regulatory region DNA binding;GO:0070064//proline-rich region binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0005515//protein binding,K10591//Endocytosis;Epstein-Barr virus infection;Ubiquitin mediated proteolysis;K05632//Ubiquitin mediated proteolysis;Endocytosis;K05633//Ubiquitin mediated proteolysis;Endocytosis;K13305//Ubiquitin mediated proteolysis;Aldosterone-regulated sodium reabsorption;Endocytosis
10417,0,31,46,21,29,0,0,36,51,0,173,1,"SPON2;spondin 2, extracellular matrix protein",GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix,GO:0045087//innate immune response;GO:0007155//cell adhesion;GO:0007411//axon guidance,GO:0046872//metal ion binding,K03995//Prion diseases;Systemic lupus erythematosus;Complement and coagulation cascades
10418,0,0,0,0,0,42,13,7,66,0,3,0,"SPON1;spondin 1, extracellular matrix protein",GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion,GO:0005515//protein binding,K04596//p53 signaling pathway
10419,0,52,25,20,19,10,0,130,35,0,0,0,PRMT5;protein arginine methyltransferase 5,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0034709//methylosome;GO:0005829//cytosol,"GO:0008283//cell proliferation;GO:0034660//ncRNA metabolic process;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0000387//spliceosomal snRNP assembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043985//histone H4-R3 methylation;GO:0010467//gene expression;GO:0042118//endothelial cell activation;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0035246//peptidyl-arginine N-methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0007088//regulation of mitosis",GO:0008168//methyltransferase activity;GO:0005515//protein binding;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0043021//ribonucleoprotein complex binding;GO:0008469//histone-arginine N-methyltransferase activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0001046//core promoter sequence-specific DNA binding,K02516//RNA transport;Cell cycle - yeast
10420,0,0,2,8,153,0,37,0,43,0,1,0,TESK2;testis-specific kinase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0030036//actin cytoskeleton organization;GO:0048041//focal adhesion assembly;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007283//spermatogenesis,GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity,-
10421,0,1,0,5,47,24,26,0,30,0,0,0,CD2BP2;CD2 (cytoplasmic tail) binding protein 2,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0005682//U5 snRNP;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0010923//negative regulation of phosphatase activity",GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding,-
10422,0,0,0,0,0,17,9,82,34,0,0,0,UBAC1;UBA domain containing 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
10423,0,0,28,0,1,0,0,27,0,0,0,0,CDIPT;CDP-diacylglycerol--inositol 3-phosphatidyltransferase,GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0046341//CDP-diacylglycerol metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0044281//small molecule metabolic process,GO:0003881//CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity;GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0043178//alcohol binding;GO:0019992//diacylglycerol binding,K00999//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Glycerophospholipid metabolism
10424,1,113,1,5,28,20,10,0,16,0,0,0,PGRMC2;progesterone receptor membrane component 2,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0043401//steroid hormone mediated signaling pathway,GO:0003707//steroid hormone receptor activity;GO:0020037//heme binding;GO:0005496//steroid binding,-
10425,0,0,0,9,67,19,0,0,12,0,19,0,ARIH2;ariadne RBR E3 ubiquitin protein ligase 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071425//hematopoietic stem cell proliferation;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0048588//developmental cell growth;GO:0000209//protein polyubiquitination;GO:0007275//multicellular organismal development;GO:0070936//protein K48-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination,GO:0003676//nucleic acid binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
10426,62,21,0,5,26,17,21,0,29,0,0,103,"TUBGCP3;tubulin, gamma complex associated protein 3",GO:0016020//membrane;GO:0005814//centriole;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005827//polar microtubule;GO:0005819//spindle,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007338//single fertilization;GO:0007020//microtubule nucleation,GO:0043015//gamma-tubulin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005198//structural molecule activity;GO:0005515//protein binding,K01769//Purine metabolism
10427,0,0,0,0,1,0,0,0,0,0,0,0,SEC24B;SEC24 family member B,GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0030127//COPII vesicle coat;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0048471//perinuclear region of cytoplasm,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044281//small molecule metabolic process;GO:0016192//vesicle-mediated transport;GO:0060463//lung lobe morphogenesis;GO:0060088//auditory receptor cell stereocilium organization;GO:0021747//cochlear nucleus development;GO:0001843//neural tube closure;GO:0006886//intracellular protein transport;GO:0048208//COPII vesicle coating;GO:0035909//aorta morphogenesis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0003151//outflow tract morphogenesis;GO:0043687//post-translational protein modification;GO:0060982//coronary artery morphogenesis;GO:0044267//cellular protein metabolic process;GO:0061156//pulmonary artery morphogenesis;GO:0061024//membrane organization;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0005215//transporter activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K14007//Protein processing in endoplasmic reticulum
10428,0,0,0,14,13,0,0,0,0,229,0,0,CFDP1;craniofacial development protein 1,-,GO:0007155//cell adhesion;GO:0008360//regulation of cell shape;GO:0007275//multicellular organismal development;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0042127//regulation of cell proliferation,-,-
1043,0,15,0,0,1,0,0,30,4,0,0,0,CD52;CD52 molecule,GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0031225//anchored component of membrane,GO:0045730//respiratory burst;GO:0007204//positive regulation of cytosolic calcium ion concentration,-,-
10430,0,0,0,0,0,15,32,0,0,0,0,0,TMEM147;transmembrane protein 147,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
10432,0,0,0,0,11,9,0,0,21,0,0,0,RBM14;RNA binding motif protein 14,GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex,GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0006260//DNA replication;GO:0042921//glucocorticoid receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0009725//response to hormone;GO:0006310//DNA recombination,"GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0030674//protein binding, bridging;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003723//RNA binding",-
10434,0,72,0,28,79,19,0,0,3,0,25,0,LYPLA1;lysophospholipase I,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0050999//regulation of nitric-oxide synthase activity;GO:0002084//protein depalmitoylation;GO:0006631//fatty acid metabolic process;GO:0046209//nitric oxide metabolic process;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0044281//small molecule metabolic process,GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0004622//lysophospholipase activity,K06128//Glycerophospholipid metabolism
10435,0,0,0,0,0,8,0,0,50,0,0,0,CDC42EP2;CDC42 effector protein (Rho GTPase binding) 2,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm,GO:0007015//actin filament organization;GO:0031274//positive regulation of pseudopodium assembly;GO:0008360//regulation of cell shape;GO:0031334//positive regulation of protein complex assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0030036//actin cytoskeleton organization;GO:0032321//positive regulation of Rho GTPase activity,GO:0001515//opioid peptide activity;GO:0017049//GTP-Rho binding;GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity,-
10436,0,36,0,10,70,12,0,0,13,0,17,137,EMG1;EMG1 N1-specific pseudouridine methyltransferase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0031167//rRNA methylation;GO:0006364//rRNA processing;GO:0042274//ribosomal small subunit biogenesis,GO:0003723//RNA binding;GO:0070037//rRNA (pseudouridine) methyltransferase activity;GO:0019843//rRNA binding;GO:0044822//poly(A) RNA binding,K14568//Ribosome biogenesis in eukaryotes
10437,4,0,0,0,0,0,1,0,15,0,0,0,"IFI30;interferon, gamma-inducible protein 30",GO:0043202//lysosomal lumen;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0030054//cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0055114//oxidation-reduction process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050821//protein stabilization;GO:0019221//cytokine-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0048147//negative regulation of fibroblast proliferation;GO:0060333//interferon-gamma-mediated signaling pathway,"GO:0016667//oxidoreductase activity, acting on a sulfur group of donors",K08059//Antigen processing and presentation
10438,0,0,0,18,23,0,0,0,8,0,0,0,C1D;C1D nuclear receptor corepressor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000176//nuclear exosome (RNase complex);GO:0005730//nucleolus;GO:0017053//transcriptional repressor complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0000460//maturation of 5.8S rRNA",GO:0003714//transcription corepressor activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003677//DNA binding,K12592//RNA degradation
10439,0,0,0,0,0,1,0,51,13,0,0,0,OLFM1;olfactomedin 1,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0030054//cell junction;GO:0045202//synapse;GO:0005615//extracellular space,GO:0007399//nervous system development;GO:1902430//negative regulation of beta-amyloid formation;GO:2001223//negative regulation of neuron migration;GO:0051259//protein oligomerization,GO:0001540//beta-amyloid binding;GO:0005515//protein binding,-
1044,0,0,0,0,0,0,0,0,19,0,0,0,CDX1;caudal type homeobox 1,GO:0005634//nucleus,GO:0009887//organ morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060349//bone morphogenesis;GO:0009952//anterior/posterior pattern specification,GO:0005515//protein binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
10440,0,7,0,27,27,0,0,0,0,0,0,0,TIMM17A;translocase of inner mitochondrial membrane 17 homolog A (yeast),GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0031305//integral component of mitochondrial inner membrane,GO:0006626//protein targeting to mitochondrion;GO:0071806//protein transmembrane transport;GO:0044267//cellular protein metabolic process,GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity,-
10443,0,0,0,80,56,20,0,0,1,0,0,0,N4BP2L2;NEDD4 binding protein 2-like 2,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0017053//transcriptional repressor complex,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902037//negative regulation of hematopoietic stem cell differentiation;GO:1902035//positive regulation of hematopoietic stem cell proliferation,GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0001106//RNA polymerase II transcription corepressor activity,-
10444,0,37,1,24,79,11,23,35,52,0,61,0,"ZER1;zyg-11 related, cell cycle regulator",GO:0031462//Cul2-RING ubiquitin ligase complex,GO:0051438//regulation of ubiquitin-protein transferase activity;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity,-
10445,0,0,0,0,14,0,33,37,32,0,1,0,MCRS1;microspherule protein 1,GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0005737//cytoplasm;GO:0031011//Ino80 complex;GO:0005634//nucleus;GO:0000123//histone acetyltransferase complex;GO:0005730//nucleolus,"GO:0006464//cellular protein modification process;GO:0043982//histone H4-K8 acetylation;GO:0006310//DNA recombination;GO:0043984//histone H4-K16 acetylation;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0006325//chromatin organization",GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0005515//protein binding,K11674//Herpes simplex infection
10446,114,0,0,0,0,36,14,0,11,0,13,1,LRRN2;leucine rich repeat neuronal 2,GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007155//cell adhesion,GO:0004872//receptor activity,K07523//Axon guidance
10447,0,46,2,1,43,0,20,0,0,0,0,0,"FAM3C;family with sequence similarity 3, member C",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0007275//multicellular organismal development,GO:0005125//cytokine activity,K09666//Other types of O-glycan biosynthesis
10449,0,1,0,1,0,0,0,0,1,44,0,0,ACAA2;acetyl-CoA acyltransferase 2,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0071456//cellular response to hypoxia;GO:1902109//negative regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0006631//fatty acid metabolic process;GO:0006695//cholesterol biosynthetic process,GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,"K07508//Fatty acid metabolism;Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;Metabolic pathways;Fatty acid elongation;Microbial metabolism in diverse environments;Benzoate degradation"
1045,0,0,0,0,0,0,0,0,30,0,5,0,CDX2;caudal type homeobox 2,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome,"GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045597//positive regulation of cell differentiation;GO:0060711//labyrinthine layer development;GO:0008333//endosome to lysosome transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0035019//somatic stem cell maintenance;GO:0001568//blood vessel development;GO:0001829//trophectodermal cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0008284//positive regulation of cell proliferation",GO:0003714//transcription corepressor activity;GO:0003690//double-stranded DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10450,0,0,0,0,1,0,29,0,28,0,11,0,PPIE;peptidylprolyl isomerase E (cyclophilin E),GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome;GO:0045070//positive regulation of viral genome replication",GO:0016018//cyclosporin A binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity,K09564//Spliceosome
10451,0,0,0,0,0,10,22,0,96,270,0,1,VAV3;vav 3 guanine nucleotide exchange factor,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0001525//angiogenesis;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0009967//positive regulation of signal transduction;GO:0030890//positive regulation of B cell proliferation;GO:0050853//B cell receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0030593//neutrophil chemotaxis;GO:0032855//positive regulation of Rac GTPase activity;GO:0006974//cellular response to DNA damage stimulus;GO:0032314//regulation of Rac GTPase activity;GO:0030168//platelet activation;GO:0007229//integrin-mediated signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0007596//blood coagulation;GO:0006906//vesicle fusion;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0030032//lamellipodium assembly,GO:0046872//metal ion binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005096//GTPase activator activity;GO:0005070//SH3/SH2 adaptor activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005154//epidermal growth factor receptor binding,K05730//Focal adhesion;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;B cell receptor signaling pathway;Chemokine signaling pathway;Fc epsilon RI signaling pathway
10452,0,1,0,11,8,0,10,0,24,0,0,0,TOMM40;translocase of outer mitochondrial membrane 40 homolog (yeast),GO:0031307//integral component of mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0046930//pore complex,GO:0006626//protein targeting to mitochondrion;GO:0006811//ion transport;GO:0044267//cellular protein metabolic process;GO:0071806//protein transmembrane transport,GO:0015288//porin activity;GO:0008320//protein transmembrane transporter activity,K11518//Amyotrophic lateral sclerosis (ALS)
10454,88,1,0,5,1,0,55,0,14,104,5,1,TAB1;TGF-beta activated kinase 1/MAP3K7 binding protein 1,GO:0005730//nucleolus;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043234//protein complex,"GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0000187//activation of MAPK activity;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007254//JNK cascade;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0000185//activation of MAPKKK activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0001701//in utero embryonic development;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0030324//lung development;GO:0003007//heart morphogenesis;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway",GO:0019209//kinase activator activity;GO:0032403//protein complex binding;GO:0003824//catalytic activity;GO:0008047//enzyme activator activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0005515//protein binding,K04403//NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway;Osteoclast differentiation;Toxoplasmosis;Leishmaniasis;MAPK signaling pathway;Herpes simplex infection;Epstein-Barr virus infection
10455,0,88,0,37,58,4,0,0,0,0,0,37,ECI2;enoyl-CoA delta isomerase 2,GO:0005782//peroxisomal matrix;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005730//nucleolus,GO:0009062//fatty acid catabolic process;GO:0008152//metabolic process,GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0000062//fatty-acyl-CoA binding;GO:0005102//receptor binding,K13239//Fatty acid metabolism;Peroxisome
10456,0,9,0,20,97,0,0,0,0,0,0,0,HAX1;HCLS1 associated protein X-1,GO:0016529//sarcoplasmic reticulum;GO:0005739//mitochondrion;GO:0015629//actin cytoskeleton;GO:0005635//nuclear envelope;GO:0005667//transcription factor complex;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005783//endoplasmic reticulum;GO:0031965//nuclear membrane;GO:0030027//lamellipodium,GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0042981//regulation of apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0030833//regulation of actin filament polymerization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030854//positive regulation of granulocyte differentiation;GO:0071345//cellular response to cytokine stimulus,GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0019966//interleukin-1 binding,-
10457,0,0,0,0,0,0,0,0,52,0,0,0,GPNMB;glycoprotein (transmembrane) nmb,GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane,GO:0001649//osteoblast differentiation;GO:0030282//bone mineralization;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion,GO:0008201//heparin binding;GO:0005178//integrin binding,-
10458,0,55,0,0,5,32,64,76,99,0,2,0,BAIAP2;BAI1-associated protein 2,GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030175//filopodium,GO:0032956//regulation of actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0008286//insulin receptor signaling pathway;GO:0051764//actin crosslink formation;GO:0048167//regulation of synaptic plasticity;GO:0016358//dendrite development;GO:0051017//actin filament bundle assembly;GO:0046847//filopodium assembly;GO:0007409//axonogenesis;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0009617//response to bacterium;GO:0045087//innate immune response,GO:0008022//protein C-terminus binding;GO:0008093//cytoskeletal adaptor activity;GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0017124//SH3 domain binding,K05627//Regulation of actin cytoskeleton;Adherens junction
10459,0,0,0,0,3,0,0,5,29,0,10,0,MAD2L2;MAD2 mitotic arrest deficient-like 2 (yeast),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0016035//zeta DNA polymerase complex;GO:0005680//anaphase-promoting complex,"GO:0006302//double-strand break repair;GO:0007067//mitotic nuclear division;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0006281//DNA repair;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0042177//negative regulation of protein catabolic process;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007015//actin filament organization;GO:0007094//mitotic spindle assembly checkpoint;GO:0060564//negative regulation of mitotic anaphase-promoting complex activity;GO:0001558//regulation of cell growth;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042772//DNA damage response, signal transduction resulting in transcription;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000678//negative regulation of transcription regulatory region DNA binding",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005515//protein binding;GO:0008432//JUN kinase binding,K13728//Progesterone-mediated oocyte maturation;Shigellosis;Cell cycle;Oocyte meiosis;Bacterial invasion of epithelial cells
10460,75,0,15,0,0,45,23,76,14,16,0,0,"TACC3;transforming, acidic coiled-coil containing protein 3",GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0032886//regulation of microtubule-based process;GO:0051726//regulation of cell cycle;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0030097//hemopoiesis;GO:0001666//response to hypoxia;GO:0021987//cerebral cortex development;GO:0030953//astral microtubule organization;GO:0022027//interkinetic nuclear migration;GO:0022008//neurogenesis,GO:0005515//protein binding;GO:0019904//protein domain specific binding,K14283//RNA transport
10461,0,0,0,0,0,0,0,0,40,0,0,0,"MERTK;MER proto-oncogene, tyrosine kinase",GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0001750//photoreceptor outer segment;GO:0005886//plasma membrane;GO:0016028//rhabdomere;GO:0005615//extracellular space,GO:0051250//negative regulation of lymphocyte activation;GO:0043277//apoptotic cell clearance;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0060068//vagina development;GO:0043491//protein kinase B signaling;GO:0007267//cell-cell signaling;GO:0007596//blood coagulation;GO:0007166//cell surface receptor signaling pathway;GO:0007283//spermatogenesis;GO:0006468//protein phosphorylation;GO:0032940//secretion by cell;GO:0060041//retina development in camera-type eye;GO:0001779//natural killer cell differentiation;GO:0006909//phagocytosis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030168//platelet activation;GO:0050766//positive regulation of phagocytosis;GO:0050900//leukocyte migration,GO:0005515//protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding,-
10462,0,0,0,0,0,17,29,0,0,105,0,0,"CLEC10A;C-type lectin domain family 10, member A",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0045087//innate immune response;GO:0006897//endocytosis,GO:0030246//carbohydrate binding,-
10463,0,26,1,103,317,0,35,0,10,0,2,0,"SLC30A9;solute carrier family 30 (zinc transporter), member 9",GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0016021//integral component of membrane,"GO:0006829//zinc ion transport;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0008324//cation transmembrane transporter activity;GO:0003682//chromatin binding,-
10464,0,0,1,10,8,25,16,0,11,0,0,0,PIBF1;progesterone immunomodulatory binding factor 1,GO:0005813//centrosome,-,GO:0005515//protein binding,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
10465,0,23,35,0,20,18,0,0,17,0,2,0,PPIH;peptidylprolyl isomerase H (cyclophilin H),GO:0016607//nuclear speck;GO:0071001//U4/U6 snRNP;GO:0005681//spliceosomal complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0005737//cytoplasm,"GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome;GO:0045070//positive regulation of viral genome replication;GO:0006461//protein complex assembly;GO:0000413//protein peptidyl-prolyl isomerization",GO:0005515//protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0043021//ribonucleoprotein complex binding;GO:0016018//cyclosporin A binding,K09567//Spliceosome
10466,0,458,360,559,750,0,63,88,60,0,313,1,COG5;component of oligomeric golgi complex 5,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0017119//Golgi transport complex,GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0005515//protein binding,-
10468,0,0,0,0,0,0,0,0,7,0,0,0,FST;follistatin,GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0002244//hematopoietic progenitor cell differentiation;GO:0051798//positive regulation of hair follicle development;GO:0031069//hair follicle morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007389//pattern specification process;GO:0030509//BMP signaling pathway;GO:0007276//gamete generation;GO:0008585//female gonad development;GO:0045596//negative regulation of cell differentiation;GO:0043616//keratinocyte proliferation;GO:0001501//skeletal system development,GO:0043395//heparan sulfate proteoglycan binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0048185//activin binding,K04661//TGF-beta signaling pathway
10469,40,0,0,0,12,0,0,64,18,43,0,0,TIMM44;translocase of inner mitochondrial membrane 44 homolog (yeast),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0071806//protein transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion,GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
1047,0,0,0,10,0,0,0,0,11,0,0,0,CLGN;calmegin,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope,GO:0006457//protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0006461//protein complex assembly;GO:0007338//single fertilization,GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding,-
10472,0,0,0,0,25,0,0,0,18,3,0,0,ZBTB18;zinc finger and BTB domain containing 18,GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0000228//nuclear chromosome;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus,"GO:0001701//in utero embryonic development;GO:0021549//cerebellum development;GO:0051302//regulation of cell division;GO:0048666//neuron development;GO:0021766//hippocampus development;GO:0007519//skeletal muscle tissue development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021987//cerebral cortex development;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048872//homeostasis of number of cells",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10473,0,15,0,1,91,0,32,0,0,0,0,0,HMGN4;high mobility group nucleosomal binding domain 4,GO:0005634//nucleus;GO:0000785//chromatin,-,GO:0031492//nucleosomal DNA binding,-
10474,83,312,194,285,627,7,35,363,91,1,625,133,TADA3;transcriptional adaptor 3,GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0030914//STAGA complex;GO:0072686//mitotic spindle;GO:0005730//nucleolus;GO:0033276//transcription factor TFTC complex;GO:0005622//intracellular,"GO:0030520//intracellular estrogen receptor signaling pathway;GO:0031063//regulation of histone deacetylation;GO:0090043//regulation of tubulin deacetylation;GO:0006351//transcription, DNA-templated;GO:0001932//regulation of protein phosphorylation;GO:0006325//chromatin organization;GO:0010628//positive regulation of gene expression;GO:0031647//regulation of protein stability;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007067//mitotic nuclear division;GO:0043966//histone H3 acetylation;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0019904//protein domain specific binding;GO:0004402//histone acetyltransferase activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0005515//protein binding,-
10475,0,34,0,55,75,44,0,0,5,0,0,0,TRIM38;tripartite motif containing 38,GO:0005622//intracellular,GO:0032648//regulation of interferon-beta production;GO:0070936//protein K48-linked ubiquitination;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0046598//positive regulation of viral entry into host cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0050687//negative regulation of defense response to virus;GO:0045070//positive regulation of viral genome replication,GO:0004871//signal transducer activity;GO:0008270//zinc ion binding,-
10476,0,51,0,11,100,0,14,0,0,0,0,0,"ATP5H;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome",GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process,GO:0022857//transmembrane transporter activity;GO:0016887//ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity,K02138//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
10477,0,0,0,0,5,0,19,3,0,0,0,0,UBE2E3;ubiquitin-conjugating enzyme E2E 3,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0040008//regulation of growth;GO:0070979//protein K11-linked ubiquitination,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0004842//ubiquitin-protein transferase activity,K06689//Shigellosis;Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum
10478,0,21,0,0,31,0,0,0,25,0,13,0,"SLC25A17;solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17",GO:0005739//mitochondrion;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome,GO:0044255//cellular lipid metabolic process;GO:0015866//ADP transport;GO:0035349//coenzyme A transmembrane transport;GO:0044281//small molecule metabolic process;GO:1901679//nucleotide transmembrane transport;GO:0006635//fatty acid beta-oxidation;GO:0080121//AMP transport;GO:0015867//ATP transport;GO:0043132//NAD transport;GO:0001561//fatty acid alpha-oxidation;GO:0015908//fatty acid transport;GO:0035350//FAD transmembrane transport,GO:0080122//AMP transmembrane transporter activity;GO:0005515//protein binding;GO:0051087//chaperone binding;GO:0051724//NAD transporter activity;GO:0015228//coenzyme A transmembrane transporter activity;GO:0044610//FMN transmembrane transporter activity;GO:0005347//ATP transmembrane transporter activity;GO:0015230//FAD transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity,K13354//Peroxisome
10479,0,0,0,0,0,14,2,0,47,46,0,0,"SLC9A6;solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6",GO:0043679//axon terminus;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0005789//endoplasmic reticulum membrane;GO:0055038//recycling endosome membrane;GO:0005739//mitochondrion;GO:0031901//early endosome membrane,GO:0006885//regulation of pH;GO:0048812//neuron projection morphogenesis;GO:0097484//dendrite extension;GO:1902600//hydrogen ion transmembrane transport;GO:0051386//regulation of neurotrophin TRK receptor signaling pathway;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0050808//synapse organization;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0048675//axon extension;GO:0060996//dendritic spine development;GO:0006810//transport,GO:0015385//sodium:proton antiporter activity,K12041//Cardiac muscle contraction
1048,0,0,0,0,0,0,2,61,13,0,2,0,CEACAM5;carcinoembryonic antigen-related cell adhesion molecule 5,GO:0031225//anchored component of membrane;GO:0071575//integral component of external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane,GO:2000811//negative regulation of anoikis;GO:0010832//negative regulation of myotube differentiation;GO:0043066//negative regulation of apoptotic process;GO:0034109//homotypic cell-cell adhesion,GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0034235//GPI anchor binding,-
10480,0,42,0,36,69,0,4,3,49,0,0,0,"EIF3M;eukaryotic translation initiation factor 3, subunit M","GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0033290//eukaryotic 48S preinitiation complex",GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0002183//cytoplasmic translational initiation;GO:0006413//translational initiation,GO:0031369//translation initiation factor binding;GO:0005515//protein binding;GO:0003743//translation initiation factor activity,-
10481,0,172,1,64,273,10,20,2,9,0,0,0,HOXB13;homeobox B13,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0009611//response to wounding;GO:0006355//regulation of transcription, DNA-templated;GO:0001525//angiogenesis;GO:0008544//epidermis development;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0033574//response to testosterone",GO:0043565//sequence-specific DNA binding,-
10482,0,0,0,0,1,5,31,0,25,0,12,30,NXF1;nuclear RNA export factor 1,GO:0042405//nuclear inclusion body;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0000346//transcription export complex;GO:0005643//nuclear pore;GO:0005654//nucleoplasm,GO:0016973//poly(A)+ mRNA export from nucleus;GO:0010467//gene expression;GO:0006406//mRNA export from nucleus;GO:0016032//viral process,GO:0005487//nucleocytoplasmic transporter activity;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding,K14284//Influenza A;Ribosome biogenesis in eukaryotes;mRNA surveillance pathway;RNA transport;Herpes simplex infection
10483,94,131,2,39,240,45,38,8,49,0,3,0,SEC23B;Sec23 homolog B (S. cerevisiae),GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030127//COPII vesicle coat;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm,GO:0016192//vesicle-mediated transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport,GO:0008270//zinc ion binding,K14006//Protein processing in endoplasmic reticulum
10484,6,0,0,12,62,10,30,0,36,39,0,0,SEC23A;Sec23 homolog A (S. cerevisiae),GO:0005829//cytosol;GO:0030127//COPII vesicle coat;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030868//smooth endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane,GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0044281//small molecule metabolic process;GO:0048208//COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0043687//post-translational protein modification;GO:0016192//vesicle-mediated transport;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I,GO:0008270//zinc ion binding;GO:0005515//protein binding,K14006//Protein processing in endoplasmic reticulum
10486,0,0,0,0,0,0,0,0,54,296,2,0,"CAP2;CAP, adenylate cyclase-associated protein, 2 (yeast)",GO:0005886//plasma membrane,GO:0007163//establishment or maintenance of cell polarity;GO:0007010//cytoskeleton organization;GO:0007411//axon guidance;GO:0007165//signal transduction;GO:0007190//activation of adenylate cyclase activity,GO:0003779//actin binding,-
10487,0,84,1,112,210,4,3,0,1,0,0,0,"CAP1;CAP, adenylate cyclase-associated protein 1 (yeast)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0030864//cortical actin cytoskeleton,GO:0030036//actin cytoskeleton organization;GO:0007190//activation of adenylate cyclase activity;GO:0007596//blood coagulation;GO:0006898//receptor-mediated endocytosis;GO:0007411//axon guidance;GO:0002576//platelet degranulation;GO:0007163//establishment or maintenance of cell polarity;GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0001667//ameboidal cell migration,GO:0003779//actin binding,-
10488,63,128,28,16,147,0,0,22,29,0,8,0,CREB3;cAMP responsive element binding protein 3,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0043025//neuronal cell body;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016604//nuclear body,"GO:0006351//transcription, DNA-templated;GO:0050930//induction of positive chemotaxis;GO:0051928//positive regulation of calcium ion transport;GO:0090026//positive regulation of monocyte chemotaxis;GO:0030335//positive regulation of cell migration;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0090045//positive regulation of deacetylase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001558//regulation of cell growth;GO:0019043//establishment of viral latency;GO:0019046//release from viral latency;GO:0006366//transcription from RNA polymerase II promoter;GO:2000326//negative regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0006935//chemotaxis;GO:0002230//positive regulation of defense response to virus by host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045786//negative regulation of cell cycle;GO:0006986//response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0016032//viral process;GO:0042127//regulation of cell proliferation",GO:0031726//CCR1 chemokine receptor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0008140//cAMP response element binding protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding,K09048//Melanogenesis;Amphetamine addiction;Vasopressin-regulated water reabsorption;Prostate cancer;Alcoholism;Dopaminergic synapse;Cocaine addiction;Huntington's disease;Cholinergic synapse
10489,1,5,0,2,50,0,0,0,34,0,0,0,LRRC41;leucine rich repeat containing 41,GO:0016020//membrane,GO:0016567//protein ubiquitination,-,-
10490,1,567,204,641,1093,1,89,4875,441,255,1337,3,VTI1B;vesicle transport through interaction with t-SNAREs 1B,GO:0005765//lysosomal membrane;GO:0043025//neuronal cell body;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0031201//SNARE complex;GO:0048471//perinuclear region of cytoplasm;GO:0031902//late endosome membrane,GO:0008283//cell proliferation;GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion;GO:0006904//vesicle docking involved in exocytosis;GO:0000046//autophagic vacuole fusion;GO:0006886//intracellular protein transport,GO:0000149//SNARE binding,K11152//Retinol metabolism;Metabolic pathways;K08493//SNARE interactions in vesicular transport
10491,11,37,0,9,42,8,19,0,16,0,0,0,CRTAP;cartilage associated protein,GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005578//proteinaceous extracellular matrix;GO:0032991//macromolecular complex,GO:0007283//spermatogenesis;GO:0018400//peptidyl-proline hydroxylation to 3-hydroxy-L-proline;GO:0061077//chaperone-mediated protein folding;GO:0050821//protein stabilization;GO:1901874//negative regulation of post-translational protein modification;GO:0030198//extracellular matrix organization,GO:0032403//protein complex binding,-
10492,0,89,3,124,517,0,20,72,26,30,0,0,"SYNCRIP;synaptotagmin binding, cytoplasmic RNA interacting protein",GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005783//endoplasmic reticulum;GO:0097452//GAIT complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0070937//CRD-mediated mRNA stability complex;GO:0071204//histone pre-mRNA 3'end processing complex,"GO:0001649//osteoblast differentiation;GO:0006396//RNA processing;GO:0016032//viral process;GO:0071346//cellular response to interferon-gamma;GO:0017148//negative regulation of translation;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0070934//CRD-mediated mRNA stabilization",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008143//poly(A) binding;GO:0003723//RNA binding,-
10493,0,8,1,5,60,17,1,0,13,0,0,0,VAT1;vesicle amine transport 1,GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0010637//negative regulation of mitochondrial fusion,GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity,K10133//p53 signaling pathway;K00344//Metabolic pathways;Tyrosine metabolism;Naphthalene degradation;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites
10494,99,62,0,11,64,15,0,1,12,0,18,0,STK25;serine/threonine kinase 25,GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0050772//positive regulation of axonogenesis;GO:0051645//Golgi localization;GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0007163//establishment or maintenance of cell polarity;GO:0006979//response to oxidative stress,GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity,-
10495,0,42,0,7,0,20,17,0,21,0,0,0,ENOX2;ecto-NOX disulfide-thiol exchanger 2,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane,GO:0016049//cell growth;GO:0040008//regulation of growth;GO:0055114//oxidation-reduction process;GO:0007624//ultradian rhythm,GO:0003676//nucleic acid binding;GO:0000166//nucleotide binding;GO:0015035//protein disulfide oxidoreductase activity,-
10497,1,215,41,89,320,0,50,62,123,92,28,444,UNC13B;unc-13 homolog B (C. elegans),GO:0005829//cytosol;GO:0043195//terminal bouton;GO:0048786//presynaptic active zone;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005737//cytoplasm,"GO:0016082//synaptic vesicle priming;GO:0035556//intracellular signal transduction;GO:0007588//excretion;GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0035249//synaptic transmission, glutamatergic;GO:0060384//innervation;GO:0006915//apoptotic process;GO:0097151//positive regulation of inhibitory postsynaptic membrane potential;GO:0007528//neuromuscular junction development;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0007165//signal transduction",GO:0004872//receptor activity;GO:0019992//diacylglycerol binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity,K15293//Synaptic vesicle cycle
10498,0,16,0,44,50,0,0,0,46,0,40,0,CARM1;coactivator-associated arginine methyltransferase 1,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0051591//response to cAMP;GO:0016032//viral process;GO:0003420//regulation of growth plate cartilage chondrocyte proliferation;GO:0045600//positive regulation of fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0034971//histone H3-R17 methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0032091//negative regulation of protein binding;GO:0044255//cellular lipid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0009405//pathogenesis;GO:0016571//histone methylation;GO:0044281//small molecule metabolic process;GO:0034970//histone H3-R2 methylation;GO:0006355//regulation of transcription, DNA-templated",GO:0042054//histone methyltransferase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0016274//protein-arginine N-methyltransferase activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0070577//lysine-acetylated histone binding;GO:0035642//histone methyltransferase activity (H3-R17 specific);GO:0003713//transcription coactivator activity;GO:0008276//protein methyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0008013//beta-catenin binding;GO:0008469//histone-arginine N-methyltransferase activity,-
10499,0,47,0,68,160,38,25,48,71,0,0,0,NCOA2;nuclear receptor coactivator 2,GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010906//regulation of glucose metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0016573//histone acetylation;GO:2000273//positive regulation of receptor activity;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated",GO:0004402//histone acetyltransferase activity;GO:0004871//signal transducer activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0003682//chromatin binding;GO:0030375//thyroid hormone receptor coactivator activity;GO:0008134//transcription factor binding;GO:0005515//protein binding,-
105,12,0,1,0,0,0,1,0,77,12,14,0,"ADARB2;adenosine deaminase, RNA-specific, B2 (non-functional)",GO:0005634//nucleus,GO:0006397//mRNA processing,GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0004000//adenosine deaminase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
1050,0,0,0,15,2,20,0,0,11,0,16,0,"CEBPA;CCAAT/enhancer binding protein (C/EBP), alpha",GO:0035189//Rb-E2F complex;GO:0016363//nuclear matrix;GO:0005634//nucleus,"GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045600//positive regulation of fat cell differentiation;GO:0050872//white fat cell differentiation;GO:0048839//inner ear development;GO:0007005//mitochondrion organization;GO:0030099//myeloid cell differentiation;GO:0001892//embryonic placenta development;GO:0050873//brown fat cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030324//lung development;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0031100//organ regeneration;GO:0048469//cell maturation;GO:0000050//urea cycle;GO:0051384//response to glucocorticoid;GO:0045669//positive regulation of osteoblast differentiation;GO:0001889//liver development;GO:0030225//macrophage differentiation;GO:0006953//acute-phase response;GO:0006091//generation of precursor metabolites and energy;GO:0006351//transcription, DNA-templated;GO:0071285//cellular response to lithium ion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033274//response to vitamin B2;GO:0071407//cellular response to organic cyclic compound;GO:0008203//cholesterol metabolic process;GO:0008285//negative regulation of cell proliferation",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0071837//HMG box domain binding;GO:0003677//DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0032403//protein complex binding,K09055//Transcriptional misregulation in cancer;Pathways in cancer;Acute myeloid leukemia
10500,0,33,0,9,0,0,0,104,22,0,0,0,"SEMA6C;sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007411//axon guidance,GO:0004872//receptor activity,K06842//Axon guidance
10501,0,0,0,0,0,19,21,0,66,13,1,0,"SEMA6B;sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007399//nervous system development,GO:0030215//semaphorin receptor binding;GO:0004872//receptor activity,K06842//Axon guidance
10505,0,0,0,0,10,69,0,0,23,0,0,327,"SEMA4F;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F",GO:0005887//integral component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0007267//cell-cell signaling;GO:0030517//negative regulation of axon extension;GO:0007411//axon guidance;GO:0031290//retinal ganglion cell axon guidance;GO:0007399//nervous system development,GO:0004872//receptor activity,K06521//Axon guidance
10507,317,50,0,46,59,0,23,83,53,0,12,0,"SEMA4D;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D",GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0001934//positive regulation of protein phosphorylation;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045668//negative regulation of osteoblast differentiation;GO:0007162//negative regulation of cell adhesion;GO:0048814//regulation of dendrite morphogenesis;GO:0031344//regulation of cell projection organization;GO:0032321//positive regulation of Rho GTPase activity;GO:0043066//negative regulation of apoptotic process;GO:1900220//semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0008360//regulation of cell shape;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071526//semaphorin-plexin signaling pathway;GO:0006955//immune response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0070486//leukocyte aggregation;GO:0043931//ossification involved in bone maturation;GO:0048672//positive regulation of collateral sprouting;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0030215//semaphorin receptor binding;GO:0004872//receptor activity;GO:0005102//receptor binding,K06521//Axon guidance
10509,0,0,0,3,0,0,0,0,0,0,9,0,"SEMA4B;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B",GO:0045202//synapse;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007399//nervous system development;GO:0030154//cell differentiation,GO:0004872//receptor activity,K06521//Axon guidance
1051,0,0,0,0,19,0,0,0,0,0,4,0,"CEBPB;CCAAT/enhancer binding protein (C/EBP), beta","GO:0000779//condensed chromosome, centromeric region;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm","GO:0045892//negative regulation of transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0050873//brown fat cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001892//embryonic placenta development;GO:0045600//positive regulation of fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0034976//response to endoplasmic reticulum stress;GO:0043524//negative regulation of neuron apoptotic process;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0006955//immune response;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0033598//mammary gland epithelial cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0006953//acute-phase response;GO:0045669//positive regulation of osteoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0060644//mammary gland epithelial cell differentiation;GO:0071230//cellular response to amino acid stimulus",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0035259//glucocorticoid receptor binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K10048//Transcriptional misregulation in cancer;Tuberculosis
10512,0,16,1,19,77,50,3,1,88,114,14,0,"SEMA3C;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005615//extracellular space,GO:0001974//blood vessel remodeling;GO:0009791//post-embryonic development;GO:0001756//somitogenesis;GO:0021915//neural tube development;GO:0003151//outflow tract morphogenesis;GO:0042493//response to drug;GO:0007411//axon guidance;GO:0001755//neural crest cell migration;GO:0003215//cardiac right ventricle morphogenesis;GO:0003350//pulmonary myocardium development;GO:0060174//limb bud formation;GO:0006955//immune response;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching,GO:0030215//semaphorin receptor binding;GO:0004872//receptor activity,K06840//Axon guidance
10513,0,58,1,43,144,4,9,79,67,0,0,0,APPBP2;amyloid beta precursor protein (cytoplasmic tail) binding protein 2,GO:0005875//microtubule associated complex;GO:0030659//cytoplasmic vesicle membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0006886//intracellular protein transport;GO:0046907//intracellular transport;GO:0008152//metabolic process,GO:0003777//microtubule motor activity;GO:0005515//protein binding,K10407//Salmonella infection;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
10514,0,0,0,0,0,39,15,1,44,77,10,0,MYBBP1A;MYB binding protein (P160) 1a,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005730//nucleolus;GO:0042564//NLS-dependent protein nuclear import complex,"GO:0006261//DNA-dependent DNA replication;GO:0042149//cellular response to glucose starvation;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0022904//respiratory electron transport chain;GO:0071158//positive regulation of cell cycle arrest;GO:0006913//nucleocytoplasmic transport;GO:0001649//osteoblast differentiation",GO:0008134//transcription factor binding;GO:0044822//poly(A) RNA binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003887//DNA-directed DNA polymerase activity,-
10516,0,0,0,0,0,0,0,0,18,0,0,0,FBLN5;fibulin 5,GO:0005578//proteinaceous extracellular matrix;GO:0071953//elastic fiber;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:2000121//regulation of removal of superoxide radicals;GO:0030198//extracellular matrix organization;GO:0001558//regulation of cell growth;GO:0007160//cell-matrix adhesion;GO:0034394//protein localization to cell surface;GO:0048251//elastic fiber assembly,GO:0008022//protein C-terminus binding;GO:0005509//calcium ion binding;GO:0005178//integrin binding;GO:0005515//protein binding,K08023//TGF-beta signaling pathway
10517,0,0,0,0,0,14,43,0,35,0,0,0,FBXW10;F-box and WD repeat domain containing 10,-,-,-,-
10518,0,37,0,0,0,0,0,0,0,0,0,0,CIB2;calcium and integrin binding family member 2,GO:0001917//photoreceptor inner segment;GO:0005927//muscle tendon junction;GO:0042383//sarcolemma;GO:0072562//blood microparticle;GO:0031594//neuromuscular junction,GO:0055074//calcium ion homeostasis;GO:0045494//photoreceptor cell maintenance,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005178//integrin binding,K06268//HTLV-I infection;B cell receptor signaling pathway;Calcium signaling pathway;Alzheimer's disease;Osteoclast differentiation;VEGF signaling pathway;Axon guidance;Long-term potentiation;Tuberculosis;Oocyte meiosis;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Apoptosis;Glutamatergic synapse;Amphetamine addiction
10519,1,378,121,262,494,19,35,504,189,0,1150,0,CIB1;calcium and integrin binding 1 (calmyrin),GO:0016020//membrane;GO:0043005//neuron projection;GO:0032433//filopodium tip;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0071944//cell periphery;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0031982//vesicle;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0005813//centrosome;GO:0032587//ruffle membrane;GO:0042383//sarcolemma;GO:0048471//perinuclear region of cytoplasm,GO:0051898//negative regulation of protein kinase B signaling;GO:0042127//regulation of cell proliferation;GO:0030220//platelet formation;GO:0038163//thrombopoietin-mediated signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0007155//cell adhesion;GO:0001934//positive regulation of protein phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0001525//angiogenesis;GO:0001954//positive regulation of cell-matrix adhesion;GO:0001933//negative regulation of protein phosphorylation;GO:0002931//response to ischemia;GO:0030307//positive regulation of cell growth;GO:1901313//positive regulation of gene expression involved in extracellular matrix organization;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0048554//positive regulation of metalloenzyme activity;GO:0051302//regulation of cell division;GO:1990090//cellular response to nerve growth factor stimulus;GO:0007286//spermatid development;GO:0006302//double-strand break repair;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045653//negative regulation of megakaryocyte differentiation;GO:2000256//positive regulation of male germ cell proliferation;GO:0071363//cellular response to growth factor stimulus;GO:0007026//negative regulation of microtubule depolymerization;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0097191//extrinsic apoptotic signaling pathway;GO:0090314//positive regulation of protein targeting to membrane;GO:0051301//cell division;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0007113//endomitotic cell cycle;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0010977//negative regulation of neuron projection development;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0030335//positive regulation of cell migration;GO:0031122//cytoplasmic microtubule organization;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade,GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0043495//protein anchor;GO:0017016//Ras GTPase binding,K06268//Osteoclast differentiation;Alzheimer's disease;VEGF signaling pathway;HTLV-I infection;Calcium signaling pathway;B cell receptor signaling pathway;Glutamatergic synapse;Apoptosis;T cell receptor signaling pathway;Amphetamine addiction;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;Axon guidance;Tuberculosis;Long-term potentiation
1052,111,0,0,0,0,0,0,0,5,0,0,0,"CEBPD;CCAAT/enhancer binding protein (C/EBP), delta",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
10520,0,0,0,19,0,0,15,0,0,0,0,0,ZNF211;zinc finger protein 211,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
10521,0,139,6,125,519,0,23,0,22,0,0,0,DDX17;DEAD (Asp-Glu-Ala-Asp) box helicase 17,GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,"GO:2001014//regulation of skeletal muscle cell differentiation;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0006200//ATP catabolic process;GO:0006396//RNA processing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0008186//RNA-dependent ATPase activity;GO:0030331//estrogen receptor binding;GO:0003724//RNA helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity,-
10522,0,49,2,4,1,0,0,64,49,0,62,119,DEAF1;DEAF1 transcription factor,GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005576//extracellular region,GO:0009653//anatomical structure morphogenesis;GO:0048706//embryonic skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007281//germ cell development;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001843//neural tube closure,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K10053//Transcriptional misregulation in cancer;Acute myeloid leukemia;Pathways in cancer
10523,106,33,24,16,129,14,49,59,115,99,65,0,CHERP;calcium homeostasis endoplasmic reticulum protein,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0033017//sarcoplasmic reticulum membrane;GO:0016020//membrane,GO:0051533//positive regulation of NFAT protein import into nucleus;GO:0006874//cellular calcium ion homeostasis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0006396//RNA processing;GO:0008285//negative regulation of cell proliferation;GO:0007399//nervous system development,GO:0044325//ion channel binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12841//Spliceosome
10524,72,169,0,90,252,0,50,80,0,5,348,0,KAT5;K(lysine) acetyltransferase 5,GO:0048471//perinuclear region of cytoplasm;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0000812//Swr1 complex;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0032777//Piccolo NuA4 histone acetyltransferase complex,"GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0071392//cellular response to estradiol stimulus;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010212//response to ionizing radiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032703//negative regulation of interleukin-2 production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006302//double-strand break repair;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0030521//androgen receptor signaling pathway;GO:0016032//viral process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator",GO:0003713//transcription coactivator activity;GO:0032403//protein complex binding;GO:0050681//androgen receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004402//histone acetyltransferase activity;GO:0070491//repressing transcription factor binding,K11304//HTLV-I infection
10525,7,0,0,0,22,0,17,128,75,131,10,0,HYOU1;hypoxia up-regulated 1,GO:0005788//endoplasmic reticulum lumen;GO:0071682//endocytic vesicle lumen;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0005576//extracellular region;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0002931//response to ischemia;GO:0044267//cellular protein metabolic process;GO:0006950//response to stress;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0005524//ATP binding,K09486//Protein processing in endoplasmic reticulum
10526,0,0,0,31,129,0,31,0,34,0,0,0,IPO8;importin 8,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0006886//intracellular protein transport,GO:0005515//protein binding;GO:0008536//Ran GTPase binding,-
10527,0,67,1,78,292,8,1,0,52,246,0,0,IPO7;importin 7,GO:0016020//membrane;GO:0005643//nuclear pore;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0045087//innate immune response;GO:0006606//protein import into nucleus;GO:0016032//viral process,GO:0042393//histone binding;GO:0005515//protein binding;GO:0005215//transporter activity;GO:0005083//small GTPase regulator activity;GO:0008536//Ran GTPase binding,-
10528,0,26,0,11,7,0,0,0,0,0,3,0,NOP56;NOP56 ribonucleoprotein,GO:0070761//pre-snoRNP complex;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0031428//box C/D snoRNP complex,GO:0006364//rRNA processing;GO:0008219//cell death,GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030515//snoRNA binding,K14564//Ribosome biogenesis in eukaryotes
10529,36,35,0,11,48,13,20,0,141,0,7,0,NEBL;nebulette,GO:0031674//I band;GO:0030018//Z disc;GO:0001725//stress fiber;GO:0070062//extracellular vesicular exosome,GO:0071691//cardiac muscle thin filament assembly,GO:0008307//structural constituent of muscle;GO:0008092//cytoskeletal protein binding;GO:0005523//tropomyosin binding;GO:0051015//actin filament binding;GO:0031005//filamin binding;GO:0005515//protein binding,K06106//Shigellosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction;K06086//Insulin signaling pathway;PPAR signaling pathway;Adherens junction
1053,0,0,0,0,0,0,0,0,4,0,0,0,"CEBPE;CCAAT/enhancer binding protein (C/EBP), epsilon",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006909//phagocytosis;GO:0006952//defense response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071222//cellular response to lipopolysaccharide;GO:0042089//cytokine biosynthetic process;GO:0030225//macrophage differentiation;GO:0006351//transcription, DNA-templated;GO:0042742//defense response to bacterium",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K10051//Transcriptional misregulation in cancer
10531,0,1,1,10,67,4,0,0,79,102,1,0,PITRM1;pitrilysin metallopeptidase 1,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006508//proteolysis;GO:0043085//positive regulation of catalytic activity,GO:0046872//metal ion binding;GO:0008047//enzyme activator activity;GO:0004222//metalloendopeptidase activity,-
10533,95,484,199,437,966,2,3,664,236,1,1124,3,ATG7;autophagy related 7,GO:0005930//axoneme;GO:0005737//cytoplasm;GO:0000407//pre-autophagosomal structure;GO:0005829//cytosol,GO:0006464//cellular protein modification process;GO:0050877//neurological system process;GO:0010508//positive regulation of autophagy;GO:0021955//central nervous system neuron axonogenesis;GO:0071455//cellular response to hyperoxia;GO:0045732//positive regulation of protein catabolic process;GO:0031396//regulation of protein ubiquitination;GO:0039689//negative stranded viral RNA replication;GO:0034727//piecemeal microautophagy of nucleus;GO:0061025//membrane fusion;GO:0007628//adult walking behavior;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0016239//positive regulation of macroautophagy;GO:0032446//protein modification by small protein conjugation;GO:0055013//cardiac muscle cell development;GO:0006497//protein lipidation;GO:0021680//cerebellar Purkinje cell layer development;GO:0043065//positive regulation of apoptotic process;GO:0021860//pyramidal neuron development;GO:0001889//liver development;GO:0031401//positive regulation of protein modification process;GO:0043066//negative regulation of apoptotic process;GO:0030163//protein catabolic process;GO:0009791//post-embryonic development;GO:0006995//cellular response to nitrogen starvation;GO:0007005//mitochondrion organization;GO:0044805//late nucleophagy;GO:0009267//cellular response to starvation;GO:0021987//cerebral cortex development;GO:0000422//mitochondrion degradation;GO:0006520//cellular amino acid metabolic process;GO:0006501//C-terminal protein lipidation,GO:0004839//ubiquitin activating enzyme activity;GO:0019778//Atg12 activating enzyme activity;GO:0019779//Atg8 activating enzyme;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008134//transcription factor binding,K08337//Regulation of autophagy
10534,0,0,0,0,0,0,0,0,24,0,0,0,SSSCA1;Sjogren syndrome/scleroderma autoantigen 1,-,GO:0007067//mitotic nuclear division,GO:0042802//identical protein binding;GO:0005515//protein binding,-
10535,0,0,0,0,0,0,19,0,0,165,9,0,"RNASEH2A;ribonuclease H2, subunit A",GO:0032299//ribonuclease H2 complex;GO:0005634//nucleus,"GO:0006260//DNA replication;GO:0006298//mismatch repair;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0006401//RNA catabolic process",GO:0003723//RNA binding;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0046872//metal ion binding;GO:0004540//ribonuclease activity,K10743//DNA replication
10536,0,0,0,0,0,0,22,0,45,0,9,0,LEPREL2;leprecan-like 2,GO:0005788//endoplasmic reticulum lumen,GO:0019511//peptidyl-proline hydroxylation;GO:0008285//negative regulation of cell proliferation;GO:0030198//extracellular matrix organization;GO:0055114//oxidation-reduction process,GO:0031418//L-ascorbic acid binding;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0005506//iron ion binding,-
10538,0,0,0,0,0,0,0,87,15,0,0,1,"BATF;basic leucine zipper transcription factor, ATF-like",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0002320//lymphoid progenitor cell differentiation;GO:0072540//T-helper 17 cell lineage commitment;GO:0001816//cytokine production;GO:0072539//T-helper 17 cell differentiation;GO:0006974//cellular response to DNA damage stimulus;GO:0045064//T-helper 2 cell differentiation;GO:0060218//hematopoietic stem cell differentiation;GO:0045190//isotype switching;GO:0043011//myeloid dendritic cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0042832//defense response to protozoan;GO:0030330//DNA damage response, signal transduction by p53 class mediator",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
10539,0,0,24,26,31,28,0,0,5,0,0,0,GLRX3;glutaredoxin 3,GO:0005938//cell cortex;GO:0030018//Z disc;GO:0070062//extracellular vesicular exosome,GO:0045454//cell redox homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0002026//regulation of the force of heart contraction;GO:0055114//oxidation-reduction process,GO:0005080//protein kinase C binding;GO:0051536//iron-sulfur cluster binding;GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
1054,0,0,0,1,126,0,17,0,0,0,0,0,"CEBPG;CCAAT/enhancer binding protein (C/EBP), gamma",GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0016071//mRNA metabolic process;GO:0042267//natural killer cell mediated cytotoxicity;GO:0043353//enucleate erythrocyte differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001889//liver development;GO:0030183//B cell differentiation;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045739//positive regulation of DNA repair;GO:0006955//immune response;GO:0043388//positive regulation of DNA binding;GO:0006351//transcription, DNA-templated",GO:0003690//double-stranded DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding,K10049//Tuberculosis
10540,0,11,35,45,59,16,3,50,5,3,0,0,DCTN2;dynactin 2 (p50),GO:0005869//dynactin complex;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0000776//kinetochore;GO:0030286//dynein complex;GO:0031982//vesicle;GO:0030426//growth cone;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005874//microtubule,GO:0007067//mitotic nuclear division;GO:0032402//melanosome transport;GO:0007052//mitotic spindle organization;GO:0008152//metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0003774//motor activity;GO:0005515//protein binding;GO:0030507//spectrin binding,K10424//Vasopressin-regulated water reabsorption;Huntington's disease
10541,37,0,0,14,19,11,0,0,28,0,0,0,"ANP32B;acidic (leucine-rich) nuclear phosphoprotein 32 family, member B",GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045596//negative regulation of cell differentiation;GO:0060021//palate development;GO:0001944//vasculature development;GO:0006334//nucleosome assembly;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046827//positive regulation of protein export from nucleus;GO:0048839//inner ear development;GO:0021591//ventricular system development,GO:0070063//RNA polymerase binding;GO:0042393//histone binding,K11092//Spliceosome
10542,0,13,3,14,83,0,0,0,0,0,14,0,"LAMTOR5;late endosomal/lysosomal adaptor, MAPK and MTOR activator 5",GO:0005829//cytosol;GO:0071986//Ragulator complex;GO:0005764//lysosome,GO:0019079//viral genome replication;GO:0043066//negative regulation of apoptotic process;GO:0009615//response to virus;GO:0071230//cellular response to amino acid stimulus;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008361//regulation of cell size;GO:0043547//positive regulation of GTPase activity;GO:0032008//positive regulation of TOR signaling;GO:0061462//protein localization to lysosome,GO:0032947//protein complex scaffold;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
10544,0,0,0,0,0,11,2,0,11,0,0,0,"PROCR;protein C receptor, endothelial",GO:0005813//centrosome;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0009986//cell surface,GO:0050819//negative regulation of coagulation;GO:0007596//blood coagulation;GO:0006955//immune response;GO:0019882//antigen processing and presentation,GO:0004872//receptor activity;GO:0005515//protein binding,-
10548,0,0,0,0,0,0,0,0,20,0,31,0,TM9SF1;transmembrane 9 superfamily member 1,GO:0005765//lysosomal membrane;GO:0000421//autophagic vacuole membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane,GO:0006914//autophagy,-,-
10549,0,1,0,0,0,0,0,0,9,0,0,0,PRDX4;peroxiredoxin 4,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0045454//cell redox homeostasis;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0055114//oxidation-reduction process;GO:0072593//reactive oxygen species metabolic process;GO:2000255//negative regulation of male germ cell proliferation;GO:0007252//I-kappaB phosphorylation;GO:0030198//extracellular matrix organization;GO:0022417//protein maturation by protein folding,GO:0008379//thioredoxin peroxidase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K03386//Amoebiasis
10550,0,0,1,23,0,0,0,0,0,0,0,0,ARL6IP5;ADP-ribosylation factor-like 6 interacting protein 5,GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0043065//positive regulation of apoptotic process;GO:0015813//L-glutamate transport;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0051051//negative regulation of transport,GO:0008022//protein C-terminus binding,-
10551,0,43,0,0,2,12,0,0,14,0,0,0,AGR2;anterior gradient 2,GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005576//extracellular region,GO:0060480//lung goblet cell differentiation;GO:0070254//mucus secretion,GO:0005515//protein binding;GO:0002162//dystroglycan binding,K05360//Glutathione metabolism
10552,0,15,41,37,205,16,20,0,19,3,2,26,"ARPC1A;actin related protein 2/3 complex, subunit 1A, 41kDa",GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0045087//innate immune response;GO:0030833//regulation of actin filament polymerization,GO:0003779//actin binding,K05757//Shigellosis;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Salmonella infection
10553,0,0,0,13,48,0,0,0,18,0,3,0,"HTATIP2;HIV-1 Tat interactive protein 2, 30kDa",GO:0005737//cytoplasm;GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0016020//membrane,GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0051170//nuclear import;GO:0055114//oxidation-reduction process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0045765//regulation of angiogenesis;GO:0016032//viral process;GO:0030154//cell differentiation,GO:0016491//oxidoreductase activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity,-
10554,0,0,0,0,0,0,0,0,2,0,0,0,AGPAT1;1-acylglycerol-3-phosphate O-acyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0044281//small molecule metabolic process;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0031325//positive regulation of cellular metabolic process;GO:0001819//positive regulation of cytokine production,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13509//Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption;Glycerophospholipid metabolism
10555,0,0,1,0,0,27,0,0,14,0,11,0,AGPAT2;1-acylglycerol-3-phosphate O-acyltransferase 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0006654//phosphatidic acid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0008544//epidermis development;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13509//Glycerolipid metabolism;Fat digestion and absorption;Metabolic pathways;Glycerophospholipid metabolism
10556,0,30,0,1,16,0,0,0,0,0,0,0,RPP30;ribonuclease P/MRP 30kDa subunit,GO:0005634//nucleus;GO:0005655//nucleolar ribonuclease P complex,"GO:0008033//tRNA processing;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0004526//ribonuclease P activity;GO:0044822//poly(A) RNA binding,K03539//Ribosome biogenesis in eukaryotes;RNA transport
10557,0,0,0,1,6,0,0,0,0,29,0,0,RPP38;ribonuclease P/MRP 38kDa subunit,GO:0005634//nucleus;GO:0005655//nucleolar ribonuclease P complex,"GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0008033//tRNA processing",GO:0004526//ribonuclease P activity;GO:0005515//protein binding,K14523//RNA transport;Ribosome biogenesis in eukaryotes
10558,0,0,0,0,0,0,7,1,23,175,6,0,"SPTLC1;serine palmitoyltransferase, long chain base subunit 1",GO:0017059//serine C-palmitoyltransferase complex;GO:0016021//integral component of membrane;GO:0035339//SPOTS complex;GO:0005789//endoplasmic reticulum membrane,GO:0046512//sphingosine biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046511//sphinganine biosynthetic process,GO:0005515//protein binding;GO:0004758//serine C-palmitoyltransferase activity;GO:0030170//pyridoxal phosphate binding,K00654//Metabolic pathways;Sphingolipid metabolism
10559,0,0,0,0,0,0,0,51,76,0,7,0,"SLC35A1;solute carrier family 35 (CMP-sialic acid transporter), member A1",GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane,GO:0015782//CMP-N-acetylneuraminate transport;GO:0008643//carbohydrate transport;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0015992//proton transport;GO:0055085//transmembrane transport;GO:1901679//nucleotide transmembrane transport,GO:0005351//sugar:proton symporter activity;GO:0005456//CMP-N-acetylneuraminate transmembrane transporter activity,-
1056,0,0,0,0,1,0,0,0,16,70,0,0,CEL;carboxyl ester lipase,GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030299//intestinal cholesterol absorption;GO:0006641//triglyceride metabolic process;GO:0030157//pancreatic juice secretion;GO:0006707//cholesterol catabolic process;GO:0044241//lipid digestion;GO:0018350//protein esterification;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0009062//fatty acid catabolic process;GO:0044258//intestinal lipid catabolic process,GO:0003824//catalytic activity;GO:0016787//hydrolase activity;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0004806//triglyceride lipase activity;GO:0004771//sterol esterase activity;GO:0047372//acylglycerol lipase activity,K12298//Steroid biosynthesis;Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption;Pancreatic secretion
10560,65,0,0,0,9,0,2,0,2,0,1,0,"SLC19A2;solute carrier family 19 (thiamine transporter), member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0042723//thiamine-containing compound metabolic process;GO:0006766//vitamin metabolic process;GO:0071934//thiamine transmembrane transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0015884//folic acid transport,GO:0005515//protein binding;GO:0015403//thiamine uptake transmembrane transporter activity;GO:0008517//folic acid transporter activity,K14610//Vitamin digestion and absorption
10561,0,0,1,10,0,13,0,0,57,0,0,410,IFI44;interferon-induced protein 44,GO:0005737//cytoplasm,GO:0009615//response to virus,-,-
10562,0,0,0,0,0,0,0,0,25,0,0,0,OLFM4;olfactomedin 4,GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0030141//secretory granule;GO:0005615//extracellular space,GO:0051260//protein homooligomerization;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042981//regulation of apoptotic process;GO:0050777//negative regulation of immune response;GO:0010939//regulation of necrotic cell death;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0008152//metabolic process;GO:2000389//regulation of neutrophil extravasation;GO:0050764//regulation of phagocytosis;GO:0007155//cell adhesion,GO:0045296//cadherin binding;GO:0042803//protein homodimerization activity;GO:0003824//catalytic activity,-
10563,0,0,0,0,0,0,0,0,17,0,0,0,CXCL13;chemokine (C-X-C motif) ligand 13,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0002920//regulation of humoral immune response;GO:0007267//cell-cell signaling;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0006955//immune response;GO:2000545//negative regulation of endothelial cell chemotaxis to fibroblast growth factor;GO:0032861//activation of Rap GTPase activity;GO:0002544//chronic inflammatory response;GO:0042742//defense response to bacterium;GO:0035769//B cell chemotaxis across high endothelial venule;GO:0033625//positive regulation of integrin activation;GO:0045765//regulation of angiogenesis;GO:0002467//germinal center formation;GO:0007166//cell surface receptor signaling pathway;GO:0048535//lymph node development;GO:0010820//positive regulation of T cell chemotaxis;GO:0035754//B cell chemotaxis,GO:0031735//CCR10 chemokine receptor binding;GO:0048018//receptor agonist activity;GO:0048248//CXCR3 chemokine receptor binding;GO:0008009//chemokine activity;GO:0017134//fibroblast growth factor binding;GO:0046982//protein heterodimerization activity;GO:0008201//heparin binding;GO:0031724//CXCR5 chemokine receptor binding,K10032//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
10564,4,38,0,34,124,41,25,113,67,0,18,0,ARFGEF2;ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited),GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0043197//dendritic spine;GO:0032280//symmetric synapse;GO:0005879//axonemal microtubule;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0005815//microtubule organizing center;GO:0055037//recycling endosome;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0032279//asymmetric synapse,GO:0007032//endosome organization;GO:0043547//positive regulation of GTPase activity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0016192//vesicle-mediated transport;GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0035556//intracellular signal transduction;GO:0001881//receptor recycling;GO:0032012//regulation of ARF protein signal transduction;GO:0006887//exocytosis,GO:0017022//myosin binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0005515//protein binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0050811//GABA receptor binding;GO:0005085//guanyl-nucleotide exchange factor activity,K12495//Endocytosis
10565,90,27,0,49,140,49,14,0,23,0,15,0,ARFGEF1;ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited),GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm,GO:0016192//vesicle-mediated transport;GO:0043547//positive regulation of GTPase activity;GO:0030837//negative regulation of actin filament polymerization;GO:0090284//positive regulation of protein glycosylation in Golgi;GO:0034259//negative regulation of Rho GTPase activity;GO:0006887//exocytosis;GO:0032012//regulation of ARF protein signal transduction;GO:0015031//protein transport;GO:0007030//Golgi organization;GO:2000114//regulation of establishment of cell polarity;GO:0090303//positive regulation of wound healing,GO:0008060//ARF GTPase activator activity;GO:0017022//myosin binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0005515//protein binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K12495//Endocytosis
10566,0,0,0,14,12,0,14,0,18,20,0,0,AKAP3;A kinase (PRKA) anchor protein 3,GO:0035686//sperm fibrous sheath;GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0097228//sperm principal piece,GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0008104//protein localization;GO:0007338//single fertilization;GO:0007340//acrosome reaction;GO:0006928//cellular component movement,GO:0005515//protein binding;GO:0051018//protein kinase A binding,-
10567,0,0,0,1,0,0,0,0,0,0,0,0,RABAC1;Rab acceptor 1 (prenylated),GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005794//Golgi apparatus,-,GO:0042802//identical protein binding;GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding,-
10568,70,0,0,0,0,38,14,28,15,0,12,0,"SLC34A2;solute carrier family 34 (type II sodium/phosphate contransporter), member 2",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0031528//microvillus membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007568//aging;GO:0001701//in utero embryonic development;GO:0035435//phosphate ion transmembrane transport;GO:0009750//response to fructose;GO:0044341//sodium-dependent phosphate transport;GO:0032355//response to estradiol;GO:0006817//phosphate ion transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0030643//cellular phosphate ion homeostasis;GO:0043627//response to estrogen,GO:0031402//sodium ion binding;GO:0019904//protein domain specific binding;GO:0015321//sodium-dependent phosphate transmembrane transporter activity;GO:0042301//phosphate ion binding;GO:0005436//sodium:phosphate symporter activity,K14683//Mineral absorption
10569,0,0,0,0,130,0,22,0,77,0,0,0,SLU7;SLU7 splicing factor homolog (S. cerevisiae),GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0030532//small nuclear ribonucleoprotein complex;GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0006886//intracellular protein transport;GO:0000389//mRNA 3'-splice site recognition;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0034605//cellular response to heat;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions",GO:0008270//zinc ion binding;GO:0030628//pre-mRNA 3'-splice site binding;GO:0000386//second spliceosomal transesterification activity;GO:0005515//protein binding,K12819//Spliceosome
1057,0,0,0,0,0,24,0,0,0,0,0,0,CELP;carboxyl ester lipase pseudogene,-,-,-,K12298//Metabolic pathways;Fat digestion and absorption;Steroid biosynthesis;Glycerolipid metabolism;Pancreatic secretion
10570,0,0,1,0,0,0,0,0,29,0,0,0,DPYSL4;dihydropyrimidinase-like 4,GO:0005829//cytosol,GO:0006208//pyrimidine nucleobase catabolic process;GO:0007411//axon guidance;GO:0007399//nervous system development,"GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides",K07528//Axon guidance
10572,0,0,0,1,0,0,0,0,15,0,0,0,"SIVA1;SIVA1, apoptosis-inducing factor",GO:0005739//mitochondrion;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0009615//response to virus;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006924//activation-induced cell death of T cells;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0016032//viral process,GO:0001618//virus receptor activity;GO:0005175//CD27 receptor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
10573,0,0,0,5,35,0,0,0,0,0,0,0,MRPL28;mitochondrial ribosomal protein L28,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005761//mitochondrial ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,-
10574,180,83,2,61,180,6,18,81,0,0,5,0,"CCT7;chaperonin containing TCP1, subunit 7 (eta)",GO:0005874//microtubule;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0002199//zona pellucida receptor complex;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex;GO:0070062//extracellular vesicular exosome,GO:0044267//cellular protein metabolic process;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0007339//binding of sperm to zona pellucida,GO:0051082//unfolded protein binding;GO:0042802//identical protein binding;GO:0005524//ATP binding,-
10575,0,1,1,45,178,0,31,0,37,0,8,0,"CCT4;chaperonin containing TCP1, subunit 4 (delta)",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0002199//zona pellucida receptor complex;GO:0005874//microtubule;GO:0005634//nucleus;GO:0005832//chaperonin-containing T-complex;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0044267//cellular protein metabolic process,GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
10576,0,26,1,61,82,0,0,0,8,0,0,0,"CCT2;chaperonin containing TCP1, subunit 2 (beta)",GO:0002199//zona pellucida receptor complex;GO:0070062//extracellular vesicular exosome;GO:0005832//chaperonin-containing T-complex;GO:0005829//cytosol;GO:0044297//cell body;GO:0005874//microtubule,GO:0051131//chaperone-mediated protein complex assembly;GO:0007339//binding of sperm to zona pellucida;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0005524//ATP binding,-
10577,0,0,0,4,0,0,0,0,7,0,4,0,"NPC2;Niemann-Pick disease, type C2",GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0030301//cholesterol transport;GO:0033344//cholesterol efflux;GO:0019747//regulation of isoprenoid metabolic process;GO:0008203//cholesterol metabolic process;GO:0009615//response to virus;GO:0015914//phospholipid transport;GO:0046836//glycolipid transport;GO:0032367//intracellular cholesterol transport;GO:0042632//cholesterol homeostasis,GO:0019899//enzyme binding;GO:0015485//cholesterol binding;GO:0005515//protein binding,K13443//Lysosome
10578,0,0,0,0,0,0,0,0,19,0,0,0,GNLY;granulysin,GO:0005615//extracellular space,GO:0050832//defense response to fungus;GO:0006968//cellular defense response;GO:0042742//defense response to bacterium;GO:0031640//killing of cells of other organism,-,-
10579,38,196,5,125,357,56,1,111,29,6,35,0,"TACC2;transforming, acidic coiled-coil containing protein 2",GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032886//regulation of microtubule-based process;GO:0030953//astral microtubule organization;GO:0022027//interkinetic nuclear migration;GO:0021987//cerebral cortex development;GO:0022008//neurogenesis,GO:0019904//protein domain specific binding;GO:0035257//nuclear hormone receptor binding,-
1058,69,0,0,0,0,0,0,0,0,0,0,0,CENPA;centromere protein A,"GO:0000786//nucleosome;GO:0000939//condensed chromosome inner kinetochore;GO:0000778//condensed nuclear chromosome kinetochore;GO:0005654//nucleoplasm;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region","GO:0000278//mitotic cell cycle;GO:0051382//kinetochore assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0006334//nucleosome assembly;GO:0016032//viral process;GO:0071459//protein localization to chromosome, centromeric region;GO:0000132//establishment of mitotic spindle orientation",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,-
10580,0,13,0,7,0,22,29,0,71,0,0,0,SORBS1;sorbin and SH3 domain containing 1,GO:0005899//insulin receptor complex;GO:0005913//cell-cell adherens junction;GO:0045121//membrane raft;GO:0005634//nucleus;GO:0001725//stress fiber;GO:0005915//zonula adherens;GO:0016363//nuclear matrix;GO:0005925//focal adhesion;GO:0005829//cytosol,GO:0015758//glucose transport;GO:0043149//stress fiber assembly;GO:0032869//cellular response to insulin stimulus;GO:0046889//positive regulation of lipid biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0007160//cell-matrix adhesion;GO:0006936//muscle contraction;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0008286//insulin receptor signaling pathway;GO:0048041//focal adhesion assembly;GO:0009967//positive regulation of signal transduction,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0003779//actin binding;GO:0008092//cytoskeletal protein binding;GO:0005158//insulin receptor binding;GO:0005070//SH3/SH2 adaptor activity,K06086//Insulin signaling pathway;PPAR signaling pathway;Adherens junction
10581,0,0,0,0,0,21,0,0,0,0,0,0,IFITM2;interferon induced transmembrane protein 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0035455//response to interferon-alpha;GO:0045071//negative regulation of viral genome replication;GO:0006955//immune response;GO:0035456//response to interferon-beta;GO:0034341//response to interferon-gamma;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0046597//negative regulation of viral entry into host cell,-,K06566//B cell receptor signaling pathway
10584,0,0,0,0,0,0,0,0,25,0,0,0,COLEC10;collectin sub-family member 10 (C-type lectin),GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005737//cytoplasm,-,GO:0005537//mannose binding,-
10585,60,0,40,1,1,8,45,0,54,119,2,0,POMT1;protein-O-mannosyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0016529//sarcoplasmic reticulum,GO:0007275//multicellular organismal development;GO:0006493//protein O-linked glycosylation;GO:0097502//mannosylation;GO:0030198//extracellular matrix organization;GO:0005975//carbohydrate metabolic process;GO:0035269//protein O-linked mannosylation,GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0046872//metal ion binding;GO:0000030//mannosyltransferase activity,K00728//Other types of O-glycan biosynthesis
10586,0,0,0,0,0,0,0,0,0,105,0,0,MAB21L2;mab-21-like 2 (C. elegans),GO:0005634//nucleus,GO:0007399//nervous system development;GO:0043010//camera-type eye development;GO:0001654//eye development;GO:0010172//embryonic body morphogenesis;GO:0008284//positive regulation of cell proliferation,-,-
10587,0,7,0,1,2,6,0,172,21,0,112,201,TXNRD2;thioredoxin reductase 2,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0000305//response to oxygen radical;GO:0055114//oxidation-reduction process;GO:0030097//hemopoiesis;GO:0007507//heart development;GO:0045454//cell redox homeostasis,GO:0005515//protein binding;GO:0004791//thioredoxin-disulfide reductase activity;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding,K00384//Two-component system;Pyrimidine metabolism;Selenocompound metabolism
10588,88,2,0,1,14,0,0,0,0,0,0,0,"MTHFS;5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)",GO:0005737//cytoplasm,GO:0046653//tetrahydrofolate metabolic process;GO:0015942//formate metabolic process,GO:0005542//folic acid binding;GO:0030272//5-formyltetrahydrofolate cyclo-ligase activity;GO:0005524//ATP binding,K01934//Nucleotide excision repair;Metabolic pathways;One carbon pool by folate
10589,0,64,1,0,1,12,0,0,4,147,0,0,DRAP1;DR1-associated protein 1 (negative cofactor 2 alpha),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,K08066//Tuberculosis;Antigen processing and presentation
1059,0,21,0,2,32,0,0,63,0,1,2,0,"CENPB;centromere protein B, 80kDa","GO:0005694//chromosome;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus","GO:0006355//regulation of transcription, DNA-templated",GO:0003696//satellite DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0019237//centromeric DNA binding,-
10590,0,0,0,4,0,16,0,42,30,0,0,0,"SCGN;secretagogin, EF-hand calcium binding protein",GO:0005737//cytoplasm;GO:0030658//transport vesicle membrane;GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,K14757//Endocrine and other factor-regulated calcium reabsorption
10591,0,22,0,4,6,1,0,53,0,0,0,0,DNPH1;2'-deoxynucleoside 5'-phosphate N-hydrolase 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0009159//deoxyribonucleoside monophosphate catabolic process;GO:0009116//nucleoside metabolic process;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0030855//epithelial cell differentiation;GO:0009117//nucleotide metabolic process,GO:0050144//nucleoside deoxyribosyltransferase activity;GO:0070694//deoxyribonucleoside 5'-monophosphate N-glycosidase activity;GO:0042803//protein homodimerization activity,-
10592,53,0,0,9,12,0,65,10,57,215,0,0,SMC2;structural maintenance of chromosomes 2,GO:0005829//cytosol;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000793//condensed chromosome;GO:0005654//nucleoplasm;GO:0000228//nuclear chromosome;GO:0005737//cytoplasm,GO:0000278//mitotic cell cycle;GO:0051383//kinetochore organization;GO:0045132//meiotic chromosome segregation;GO:0007076//mitotic chromosome condensation;GO:0010032//meiotic chromosome condensation,GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K06674//Cell cycle - yeast
10594,0,62,39,69,446,27,21,0,50,0,30,0,PRPF8;pre-mRNA processing factor 8,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005682//U5 snRNP,"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006397//mRNA processing",GO:0017070//U6 snRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0030623//U5 snRNA binding,K12856//Spliceosome
10595,3,0,0,0,0,0,28,0,63,0,39,0,ERN2;endoplasmic reticulum to nucleus signaling 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,"GO:0006468//protein phosphorylation;GO:0006397//mRNA processing;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007050//cell cycle arrest;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0016075//rRNA catabolic process;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0030263//apoptotic chromosome condensation",GO:0004674//protein serine/threonine kinase activity;GO:0004540//ribonuclease activity;GO:0004519//endonuclease activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
10598,0,1,0,2,44,7,15,20,12,0,3,206,"AHSA1;AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)",GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006950//response to stress;GO:0032781//positive regulation of ATPase activity,GO:0051087//chaperone binding;GO:0005515//protein binding;GO:0001671//ATPase activator activity,-
10599,0,0,0,0,0,0,39,0,22,0,1,0,"SLCO1B1;solute carrier organic anion transporter family, member 1B1",GO:0005887//integral component of plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0008206//bile acid metabolic process;GO:0044281//small molecule metabolic process;GO:0015721//bile acid and bile salt transport;GO:0015711//organic anion transport;GO:0043252//sodium-independent organic anion transport,GO:0015347//sodium-independent organic anion transmembrane transporter activity,K05043//Bile secretion
1060,0,0,0,21,22,0,0,0,41,0,0,0,CENPC;centromere protein C,"GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0005721//pericentric heterochromatin;GO:0000780//condensed nuclear chromosome, centromeric region",GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0051382//kinetochore assembly;GO:0000278//mitotic cell cycle,GO:0019237//centromeric DNA binding;GO:0003677//DNA binding,-
10600,9,30,0,25,89,5,23,0,43,0,11,0,USP16;ubiquitin specific peptidase 16,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0070537//histone H2A K63-linked deubiquitination;GO:0007067//mitotic nuclear division;GO:0007049//cell cycle;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051289//protein homotetramerization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045901//positive regulation of translational elongation;GO:0016578//histone deubiquitination;GO:0006351//transcription, DNA-templated",GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity;GO:0003713//transcription coactivator activity;GO:0042393//histone binding;GO:0004843//ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding,-
10602,0,0,0,15,30,41,0,66,67,0,9,0,CDC42EP3;CDC42 effector protein (Rho GTPase binding) 3,GO:0005737//cytoplasm;GO:0012505//endomembrane system;GO:0015629//actin cytoskeleton;GO:0016020//membrane,GO:0008360//regulation of cell shape;GO:0007165//signal transduction,GO:0005519//cytoskeletal regulatory protein binding,-
10603,0,0,0,0,0,0,36,0,10,119,0,0,SH2B2;SH2B adaptor protein 2,GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0050851//antigen receptor-mediated signaling pathway;GO:0007596//blood coagulation;GO:0050873//brown fat cell differentiation;GO:0030036//actin cytoskeleton organization;GO:0019222//regulation of metabolic process;GO:0035556//intracellular signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0001922//B-1 B cell homeostasis;GO:0019221//cytokine-mediated signaling pathway;GO:0007399//nervous system development;GO:0046578//regulation of Ras protein signal transduction;GO:0009967//positive regulation of signal transduction;GO:0007165//signal transduction;GO:0046425//regulation of JAK-STAT cascade,GO:0005070//SH3/SH2 adaptor activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0004871//signal transducer activity;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K07193//Insulin signaling pathway;Neurotrophin signaling pathway
10605,0,34,0,22,157,0,22,0,40,79,0,0,PAIP1;poly(A) binding protein interacting protein 1,GO:0005829//cytosol;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006413//translational initiation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0045727//positive regulation of translation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0048255//mRNA stabilization",GO:0003723//RNA binding;GO:0008494//translation activator activity;GO:0005515//protein binding,K14322//RNA transport
10606,0,24,0,35,73,31,10,68,40,0,0,0,"PAICS;phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase",GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0006144//purine nucleobase metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0009113//purine nucleobase biosynthetic process,GO:0005515//protein binding;GO:0004639//phosphoribosylaminoimidazolesuccinocarboxamide synthase activity;GO:0042802//identical protein binding;GO:0004638//phosphoribosylaminoimidazole carboxylase activity;GO:0005524//ATP binding,K01587//Purine metabolism;Metabolic pathways
10607,1,1,0,0,0,0,0,0,22,1,7,644,TBL3;transducin (beta)-like 3,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0032040//small-subunit processome,GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0035556//intracellular signal transduction;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005057//receptor signaling protein activity;GO:0005515//protein binding,K14555//Ribosome biogenesis in eukaryotes
10608,69,0,0,6,6,0,0,0,3,0,7,0,MXD4;MAX dimerization protein 4,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0003714//transcription corepressor activity,-
10609,118,0,0,0,0,10,0,0,6,0,0,0,LEPREL4;leprecan-like 4,GO:0000795//synaptonemal complex;GO:0000794//condensed nuclear chromosome;GO:0005730//nucleolus,GO:0007130//synaptonemal complex assembly,-,-
10610,0,57,0,2,5,0,0,0,9,0,18,0,"ST6GALNAC2;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",GO:0030173//integral component of Golgi membrane;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0097503//sialylation;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0008373//sialyltransferase activity,-
10611,88,145,5,466,888,30,18,161,55,0,0,0,PDLIM5;PDZ and LIM domain 5,GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0045211//postsynaptic membrane,GO:0061001//regulation of dendritic spine morphogenesis;GO:0051963//regulation of synapse assembly,GO:0005080//protein kinase C binding;GO:0042805//actinin binding;GO:0008270//zinc ion binding;GO:0003779//actin binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K05760//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway;VEGF signaling pathway;Leukocyte transendothelial migration;Focal adhesion;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K05631//Tight junction;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K06112//Tight junction;K11447//Transcriptional misregulation in cancer
10612,0,0,0,0,0,22,0,58,19,0,9,186,TRIM3;tripartite motif containing 3,GO:0005769//early endosome;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0007399//nervous system development;GO:0015031//protein transport,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008022//protein C-terminus binding,-
10613,90,0,1,0,8,0,0,0,76,0,0,0,ERLIN1;ER lipid raft associated 1,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0005789//endoplasmic reticulum membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0005515//protein binding,K04467//Pancreatic cancer;NF-kappa B signaling pathway;Pathways in cancer;Chemokine signaling pathway;Small cell lung cancer;Toll-like receptor signaling pathway;Prostate cancer;Chronic myeloid leukemia;Apoptosis;T cell receptor signaling pathway;MAPK signaling pathway;Herpes simplex infection;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;Acute myeloid leukemia;HTLV-I infection;Chagas disease (American trypanosomiasis);NOD-like receptor signaling pathway;B cell receptor signaling pathway;Shigellosis;Hepatitis C;Cytosolic DNA-sensing pathway;Toxoplasmosis;Adipocytokine signaling pathway;Osteoclast differentiation;Measles
10614,0,60,2,48,122,0,0,2,42,269,95,312,HEXIM1;hexamethylene bis-acetamide inducible 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007507//heart development",GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0017069//snRNA binding;GO:0005515//protein binding,-
10615,0,0,52,25,0,1,0,113,27,0,10,0,SPAG5;sperm associated antigen 5,GO:0005815//microtubule organizing center;GO:0035371//microtubule plus-end;GO:0000922//spindle pole;GO:0030496//midbody;GO:0005737//cytoplasm;GO:0000776//kinetochore;GO:0072686//mitotic spindle;GO:0000777//condensed chromosome kinetochore,GO:0007059//chromosome segregation;GO:0007051//spindle organization;GO:0000070//mitotic sister chromatid segregation;GO:0051988//regulation of attachment of spindle microtubules to kinetochore,GO:0005515//protein binding,K05291//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways;K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
10616,60,1,0,0,1,0,0,0,14,0,0,0,RBCK1;RanBP-type and C3HC4-type zinc finger containing 1,GO:0071797//LUBAC complex,GO:0000209//protein polyubiquitination;GO:0050852//T cell receptor signaling pathway;GO:0097039//protein linear polyubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0016032//viral process;GO:0060546//negative regulation of necroptotic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0043130//ubiquitin binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10617,229,26,0,7,159,13,36,58,117,0,15,0,STAMBP;STAM binding protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032154//cleavage furrow;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0006508//proteolysis;GO:0000281//mitotic cytokinesis;GO:0008284//positive regulation of cell proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0016579//protein deubiquitination;GO:0046580//negative regulation of Ras protein signal transduction;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0007259//JAK-STAT cascade,GO:0008237//metallopeptidase activity;GO:0004843//ubiquitin-specific protease activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K11866//Endocytosis
10618,0,32,0,3,54,0,0,0,73,0,4,0,TGOLN2;trans-golgi network protein 2,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005802//trans-Golgi network;GO:0030133//transport vesicle;GO:0005634//nucleus,-,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K04574//Amyotrophic lateral sclerosis (ALS);K11447//Transcriptional misregulation in cancer
1062,61,0,0,0,0,20,93,0,85,0,4,1,"CENPE;centromere protein E, 312kDa","GO:0016020//membrane;GO:0000779//condensed chromosome, centromeric region;GO:0000776//kinetochore;GO:0005694//chromosome;GO:1990023//mitotic spindle midzone;GO:0005737//cytoplasm;GO:0000778//condensed nuclear chromosome kinetochore;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0030496//midbody;GO:0000940//condensed chromosome outer kinetochore;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus",GO:0007275//multicellular organismal development;GO:0008152//metabolic process;GO:0051382//kinetochore assembly;GO:0000278//mitotic cell cycle;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007080//mitotic metaphase plate congression;GO:0006200//ATP catabolic process;GO:0007079//mitotic chromosome movement towards spindle pole;GO:0045860//positive regulation of protein kinase activity;GO:0007018//microtubule-based movement;GO:0030071//regulation of mitotic metaphase/anaphase transition,GO:0043515//kinetochore binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
10620,0,0,0,0,0,0,49,0,71,0,26,0,ARID3B;AT rich interactive domain 3B (BRIGHT-like),GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003677//DNA binding,-
10621,13,0,0,8,0,12,0,0,23,0,0,0,"POLR3F;polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa",GO:0005829//cytosol;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm,GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0045089//positive regulation of innate immune response;GO:0006386//termination of RNA polymerase III transcription;GO:0032728//positive regulation of interferon-beta production;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production,GO:0003677//DNA binding;GO:0001056//RNA polymerase III activity;GO:0005515//protein binding;GO:0003899//DNA-directed RNA polymerase activity,K03025//Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Pyrimidine metabolism;Cytosolic DNA-sensing pathway;Metabolic pathways
10622,0,0,0,1,1,0,0,0,23,0,5,0,POLR3G;polymerase (RNA) III (DNA directed) polypeptide G (32kD),GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex,GO:0045089//positive regulation of innate immune response;GO:0008283//cell proliferation;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0032481//positive regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0006386//termination of RNA polymerase III transcription;GO:0006384//transcription initiation from RNA polymerase III promoter,GO:0003899//DNA-directed RNA polymerase activity;GO:0001056//RNA polymerase III activity,K03024//Metabolic pathways;Cytosolic DNA-sensing pathway;Pyrimidine metabolism;Epstein-Barr virus infection;RNA polymerase;Purine metabolism
10623,3,0,51,8,61,21,18,33,30,0,0,0,POLR3C;polymerase (RNA) III (DNA directed) polypeptide C (62kD),GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0006386//termination of RNA polymerase III transcription;GO:0032728//positive regulation of interferon-beta production;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0045089//positive regulation of innate immune response,GO:0003899//DNA-directed RNA polymerase activity;GO:0003677//DNA binding;GO:0001056//RNA polymerase III activity,K03023//Metabolic pathways;Cytosolic DNA-sensing pathway;Pyrimidine metabolism;RNA polymerase;Epstein-Barr virus infection;Purine metabolism
10625,0,16,27,20,88,13,0,0,11,0,0,0,IVNS1ABP;influenza virus NS1A binding protein,GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0016032//viral process;GO:0006383//transcription from RNA polymerase III promoter;GO:0008380//RNA splicing;GO:0009615//response to virus,-,K15046//Influenza A
10626,0,0,0,0,0,0,0,0,28,0,0,0,TRIM16;tripartite motif containing 16,GO:0005737//cytoplasm;GO:0016605//PML body,"GO:0060416//response to growth hormone;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045618//positive regulation of keratinocyte differentiation;GO:0032526//response to retinoic acid;GO:0043967//histone H4 acetylation;GO:0046683//response to organophosphorus;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0043966//histone H3 acetylation",GO:0032089//NACHT domain binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0019966//interleukin-1 binding,-
10627,0,53,0,110,249,0,0,1,0,0,0,0,"MYL12A;myosin, light chain 12A, regulatory, non-sarcomeric",GO:0070062//extracellular vesicular exosome;GO:0001725//stress fiber;GO:0016460//myosin II complex;GO:0030018//Z disc,GO:0070527//platelet aggregation;GO:0008360//regulation of cell shape;GO:0072661//protein targeting to plasma membrane,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0035254//glutamate receptor binding,K12757//Leukocyte transendothelial migration;Focal adhesion;Tight junction;Regulation of actin cytoskeleton
10628,0,106,4,61,229,0,0,52,10,0,0,0,TXNIP;thioredoxin interacting protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol,"GO:0006606//protein import into nucleus;GO:0042127//regulation of cell proliferation;GO:0051782//negative regulation of cell division;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0043086//negative regulation of catalytic activity;GO:0030216//keratinocyte differentiation;GO:0009612//response to mechanical stimulus;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0051592//response to calcium ion;GO:0043065//positive regulation of apoptotic process;GO:0071228//cellular response to tumor cell;GO:0045087//innate immune response;GO:0042493//response to drug;GO:0009749//response to glucose;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042542//response to hydrogen peroxide",GO:0004857//enzyme inhibitor activity;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,-
10629,0,170,1,104,85,0,0,368,97,0,251,1,"TAF6L;TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa",GO:0030914//STAGA complex;GO:0000118//histone deacetylase complex,"GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0006352//DNA-templated transcription, initiation;GO:0006338//chromatin remodeling;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,K03131//Basal transcription factors;Herpes simplex infection
1063,72,0,0,0,0,11,70,0,68,71,0,0,"CENPF;centromere protein F, 350/400kDa","GO:0000776//kinetochore;GO:0045120//pronucleus;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0005730//nucleolus;GO:0030496//midbody;GO:0000940//condensed chromosome outer kinetochore;GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0000785//chromatin;GO:0000922//spindle pole;GO:0016363//nuclear matrix","GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0051310//metaphase plate congression;GO:0042493//response to drug;GO:0008283//cell proliferation;GO:0051382//kinetochore assembly;GO:0051726//regulation of cell cycle;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0007067//mitotic nuclear division;GO:0007094//mitotic spindle assembly checkpoint;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0007517//muscle organ development;GO:0016202//regulation of striated muscle tissue development;GO:0007059//chromosome segregation",GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0045502//dynein binding;GO:0008134//transcription factor binding;GO:0003682//chromatin binding;GO:0008022//protein C-terminus binding,-
10630,0,0,0,0,0,13,0,0,0,0,0,0,PDPN;podoplanin,GO:0030027//lamellipodium;GO:0016324//apical plasma membrane;GO:0001726//ruffle;GO:0031527//filopodium membrane;GO:0030175//filopodium;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0032587//ruffle membrane;GO:0031258//lamellipodium membrane;GO:0031528//microvillus membrane,GO:0000902//cell morphogenesis;GO:0030324//lung development;GO:0007399//nervous system development;GO:0006928//cellular component movement;GO:0006954//inflammatory response;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0001946//lymphangiogenesis;GO:0006865//amino acid transport;GO:0035239//tube morphogenesis;GO:0007165//signal transduction;GO:0006833//water transport;GO:0015884//folic acid transport;GO:0008283//cell proliferation;GO:0030335//positive regulation of cell migration;GO:0016337//single organismal cell-cell adhesion;GO:0051272//positive regulation of cellular component movement;GO:0008360//regulation of cell shape;GO:0010572//positive regulation of platelet activation;GO:0009790//embryo development;GO:0048286//lung alveolus development;GO:0055093//response to hyperoxia;GO:0006693//prostaglandin metabolic process,GO:0015171//amino acid transmembrane transporter activity;GO:0015250//water channel activity;GO:0005372//water transmembrane transporter activity;GO:0008517//folic acid transporter activity,K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways
10631,0,0,0,0,0,13,18,0,55,0,0,0,"POSTN;periostin, osteoblast specific factor",GO:0005802//trans-Golgi network;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0001501//skeletal system development;GO:0009888//tissue development;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0008593//regulation of Notch signaling pathway,GO:0008201//heparin binding;GO:0005515//protein binding,-
10632,0,77,1,28,183,0,0,0,19,0,0,0,"ATP5L;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome",GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0044237//cellular metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0022904//respiratory electron transport chain,GO:0016887//ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity,K02140//Metabolic pathways;Oxidative phosphorylation
10633,0,0,0,0,0,0,0,0,25,0,0,0,"RASL10A;RAS-like, family 10, member A",GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity,-
10634,0,0,0,7,1,15,0,30,51,0,0,0,GAS2L1;growth arrest-specific 2 like 1,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0005856//cytoskeleton,GO:0045647//negative regulation of erythrocyte differentiation;GO:0009267//cellular response to starvation;GO:0007050//cell cycle arrest;GO:0097067//cellular response to thyroid hormone stimulus;GO:0010629//negative regulation of gene expression;GO:0051726//regulation of cell cycle;GO:0030308//negative regulation of cell growth;GO:0007026//negative regulation of microtubule depolymerization;GO:0001578//microtubule bundle formation,GO:0046966//thyroid hormone receptor binding;GO:0008017//microtubule binding;GO:0008093//cytoskeletal adaptor activity,-
10635,0,0,0,0,0,20,1,0,16,0,0,0,RAD51AP1;RAD51 associated protein 1,GO:0005634//nucleus,GO:0000724//double-strand break repair via homologous recombination;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0071479//cellular response to ionizing radiation,GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding,-
10636,56,0,0,7,4,0,11,60,0,170,59,0,RGS14;regulator of G-protein signaling 14,GO:0016605//PML body;GO:0005634//nucleus;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016604//nuclear body;GO:0014069//postsynaptic density;GO:0005819//spindle,GO:0007051//spindle organization;GO:0006979//response to oxidative stress;GO:0007059//chromosome segregation;GO:0031914//negative regulation of synaptic plasticity;GO:0060291//long-term synaptic potentiation;GO:0043407//negative regulation of MAP kinase activity;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0007067//mitotic nuclear division;GO:0050769//positive regulation of neurogenesis;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0010070//zygote asymmetric cell division;GO:0007616//long-term memory;GO:0008542//visual learning;GO:0006913//nucleocytoplasmic transport;GO:0035556//intracellular signal transduction;GO:0007612//learning;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0043547//positive regulation of GTPase activity;GO:0051301//cell division,GO:0008017//microtubule binding;GO:0005057//receptor signaling protein activity;GO:0019901//protein kinase binding;GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0030159//receptor signaling complex scaffold activity;GO:0032794//GTPase activating protein binding;GO:0001965//G-protein alpha-subunit binding,K13765//Cocaine addiction;Phototransduction
10637,0,0,0,0,6,25,0,0,15,0,5,0,LEFTY1;left-right determination factor 1,GO:0005615//extracellular space,GO:0016049//cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0003007//heart morphogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007368//determination of left/right symmetry,GO:0005160//transforming growth factor beta receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity,K04668//TGF-beta signaling pathway
10640,0,61,0,91,168,33,24,0,43,0,49,0,EXOC5;exocyst complex component 5,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0048278//vesicle docking;GO:0044267//cellular protein metabolic process;GO:0015031//protein transport;GO:0061024//membrane organization,-,-
10641,0,0,1,2,25,1,0,0,0,0,2,0,NPRL2;nitrogen permease regulator-like 2 (S. cerevisiae),-,GO:0033673//negative regulation of kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0006468//protein phosphorylation,GO:0005096//GTPase activator activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,-
10642,90,0,0,0,0,0,0,0,38,12,36,233,IGF2BP1;insulin-like growth factor 2 mRNA binding protein 1,GO:0005829//cytosol;GO:0030424//axon;GO:0070937//CRD-mediated mRNA stability complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule;GO:0030529//ribonucleoprotein complex;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0043197//dendritic spine,GO:0042035//regulation of cytokine biosynthetic process;GO:0051028//mRNA transport;GO:0010610//regulation of mRNA stability involved in response to stress;GO:0017148//negative regulation of translation;GO:0070934//CRD-mediated mRNA stabilization;GO:0010467//gene expression,GO:0045182//translation regulator activity;GO:0005515//protein binding;GO:0048027//mRNA 5'-UTR binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding;GO:0003729//mRNA binding,-
10643,0,0,0,0,4,14,1,0,37,0,7,1,IGF2BP3;insulin-like growth factor 2 mRNA binding protein 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006412//translation;GO:0042035//regulation of cytokine biosynthetic process;GO:0051028//mRNA transport;GO:0009653//anatomical structure morphogenesis;GO:0017148//negative regulation of translation;GO:0010467//gene expression,GO:0045182//translation regulator activity;GO:0003723//RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0048027//mRNA 5'-UTR binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
10644,29,0,25,0,0,0,2,105,14,0,0,0,IGF2BP2;insulin-like growth factor 2 mRNA binding protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005829//cytosol,GO:0051028//mRNA transport;GO:0009653//anatomical structure morphogenesis;GO:0042035//regulation of cytokine biosynthetic process;GO:0010467//gene expression;GO:0017148//negative regulation of translation,GO:0045182//translation regulator activity;GO:0003730//mRNA 3'-UTR binding;GO:0048027//mRNA 5'-UTR binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
10645,53,28,1,35,59,8,33,74,72,91,0,0,"CAMKK2;calcium/calmodulin-dependent protein kinase kinase 2, beta",GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0042995//cell projection,"GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation;GO:0045859//regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0000165//MAPK cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0019722//calcium-mediated signaling",GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005509//calcium ion binding,K07359//Alcoholism;Adipocytokine signaling pathway
10647,0,0,0,0,0,0,0,0,9,0,0,0,"SCGB1D2;secretoglobin, family 1D, member 2",GO:0005615//extracellular space,-,-,-
10648,0,0,0,0,0,12,0,0,0,0,0,0,"SCGB1D1;secretoglobin, family 1D, member 1",GO:0005615//extracellular space,-,GO:0046982//protein heterodimerization activity,-
10650,0,0,0,0,0,0,0,0,27,0,0,0,SLMO1;slowmo homolog 1 (Drosophila),GO:0005758//mitochondrial intermembrane space,GO:0015914//phospholipid transport,GO:1990050//phosphatidic acid transporter activity,-
10651,0,0,0,0,27,0,0,0,9,0,0,0,MTX2;metaxin 2,GO:0005741//mitochondrial outer membrane,GO:0006839//mitochondrial transport;GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process,-,K11447//Transcriptional misregulation in cancer;K03351//Meiosis - yeast;HTLV-I infection;Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
10652,156,2,1,50,19,0,0,0,15,0,3,0,YKT6;YKT6 v-SNARE homolog (S. cerevisiae),GO:0005887//integral component of plasma membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0031201//SNARE complex;GO:0005794//Golgi apparatus;GO:0005768//endosome,"GO:0015031//protein transport;GO:0008152//metabolic process;GO:0042147//retrograde transport, endosome to Golgi;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006904//vesicle docking involved in exocytosis;GO:0006903//vesicle targeting",GO:0005484//SNAP receptor activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K08516//SNARE interactions in vesicular transport
10653,0,7,0,0,0,0,0,0,4,0,0,0,"SPINT2;serine peptidase inhibitor, Kunitz type, 2",GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0010951//negative regulation of endopeptidase activity;GO:0006928//cellular component movement,GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K15619//Transcriptional misregulation in cancer
10654,1,0,0,2,0,25,0,0,0,0,2,0,PMVK;phosphomevalonate kinase,GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane,"GO:0016310//phosphorylation;GO:0070723//response to cholesterol;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0016126//sterol biosynthetic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway",GO:0004631//phosphomevalonate kinase activity;GO:0005524//ATP binding,K13273//Terpenoid backbone biosynthesis;Metabolic pathways;Peroxisome
10655,83,0,0,0,0,11,0,0,3,0,0,0,DMRT2;doublesex and mab-3 related transcription factor 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0048706//embryonic skeletal system development;GO:0014807//regulation of somitogenesis;GO:2000287//positive regulation of myotome development;GO:0006355//regulation of transcription, DNA-templated",GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding,-
10656,0,1,0,0,14,0,20,0,9,0,0,0,"KHDRBS3;KH domain containing, RNA binding, signal transduction associated 3",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006351//transcription, DNA-templated",GO:0003723//RNA binding;GO:0017124//SH3 domain binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
10657,0,97,2,57,212,0,0,0,44,0,12,0,"KHDRBS1;KH domain containing, RNA binding, signal transduction associated 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005730//nucleolus,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0031647//regulation of protein stability;GO:0006397//mRNA processing;GO:0008283//cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0009967//positive regulation of signal transduction;GO:0007165//signal transduction;GO:0046833//positive regulation of RNA export from nucleus;GO:0007050//cell cycle arrest;GO:0045948//positive regulation of translational initiation;GO:0046831//regulation of RNA export from nucleus",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0017124//SH3 domain binding;GO:0003677//DNA binding;GO:0008266//poly(U) RNA binding;GO:0032403//protein complex binding;GO:0003723//RNA binding;GO:0005070//SH3/SH2 adaptor activity,-
10658,63,26,0,15,23,0,14,36,32,100,0,0,"CELF1;CUGBP, Elav-like family member 1",GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006397//mRNA processing;GO:0017148//negative regulation of translation;GO:0016246//RNA interference;GO:0009790//embryo development;GO:0007281//germ cell development;GO:0043484//regulation of RNA splicing;GO:0040018//positive regulation of multicellular organism growth;GO:0007286//spermatid development;GO:0006376//mRNA splice site selection,"GO:0031369//translation initiation factor binding;GO:0003729//mRNA binding;GO:0042835//BRE binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding",-
10659,0,0,0,5,9,14,0,66,39,0,0,0,"CELF2;CUGBP, Elav-like family member 2",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006397//mRNA processing;GO:0008016//regulation of heart contraction;GO:0006396//RNA processing,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
1066,0,0,0,0,0,18,0,42,35,0,0,0,CES1;carboxylesterase 1,GO:0005788//endoplasmic reticulum lumen,GO:0008152//metabolic process;GO:0009636//response to toxic substance;GO:0030855//epithelial cell differentiation,GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity,K01044//Drug metabolism - other enzymes;Metabolic pathways
10660,0,0,0,0,0,13,0,0,0,0,11,0,LBX1;ladybird homeobox 1,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0021920//regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification;GO:0048664//neuron fate determination;GO:0045665//negative regulation of neuron differentiation;GO:0001947//heart looping;GO:0021522//spinal cord motor neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell proliferation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
10663,94,0,0,0,0,0,0,0,0,0,0,0,CXCR6;chemokine (C-X-C motif) receptor 6,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0006935//chemotaxis;GO:0019079//viral genome replication;GO:0070098//chemokine-mediated signaling pathway;GO:0006954//inflammatory response,GO:0015026//coreceptor activity;GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity,K04191//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
10664,46,1,0,38,99,24,19,0,0,0,0,0,CTCF;CCCTC-binding factor (zinc finger protein),"GO:0005654//nucleoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0000793//condensed chromosome;GO:0005730//nucleolus","GO:0045893//positive regulation of transcription, DNA-templated;GO:0006349//regulation of gene expression by genetic imprinting;GO:0040030//regulation of molecular function, epigenetic;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0006351//transcription, DNA-templated;GO:0040029//regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:0010216//maintenance of DNA methylation;GO:0016568//chromatin modification;GO:0035065//regulation of histone acetylation;GO:0006306//DNA methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016584//nucleosome positioning;GO:0031060//regulation of histone methylation;GO:0007059//chromosome segregation",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0043035//chromatin insulator sequence binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003714//transcription corepressor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
10665,133,0,0,0,0,5,0,0,22,0,0,0,C6orf10;chromosome 6 open reading frame 10,GO:0005634//nucleus;GO:0016021//integral component of membrane,-,-,K00907//Focal adhesion;Gastric acid secretion;Calcium signaling pathway;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
10666,9,0,0,0,0,18,0,0,36,0,0,0,CD226;CD226 molecule,GO:0045121//membrane raft;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0060369//positive regulation of Fc receptor mediated stimulatory signaling pathway;GO:0050776//regulation of immune response;GO:0033005//positive regulation of mast cell activation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0007165//signal transduction;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0008037//cell recognition;GO:0007155//cell adhesion;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0001816//cytokine production,GO:0050839//cell adhesion molecule binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0005178//integrin binding,K06567//Cell adhesion molecules (CAMs)
10667,0,0,0,6,1,20,38,0,34,0,0,0,"FARS2;phenylalanyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0008033//tRNA processing,GO:0004826//phenylalanine-tRNA ligase activity;GO:0000287//magnesium ion binding;GO:0000049//tRNA binding;GO:0005524//ATP binding,"K01889//Biosynthesis of secondary metabolites;C5-Branched dibasic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;ABC transporters;Aminoacyl-tRNA biosynthesis"
10668,0,0,0,0,0,0,0,0,0,2,0,277,CGRRF1;cell growth regulator with ring finger domain 1,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,GO:0006950//response to stress;GO:0007050//cell cycle arrest;GO:0008285//negative regulation of cell proliferation,GO:0008270//zinc ion binding,-
10669,0,0,0,4,0,0,14,0,14,0,0,0,CGREF1;cell growth regulator with EF-hand domain 1,GO:0005576//extracellular region,GO:0006950//response to stress;GO:0030308//negative regulation of cell growth;GO:0007155//cell adhesion;GO:0007050//cell cycle arrest;GO:0008285//negative regulation of cell proliferation,GO:0005509//calcium ion binding,K00846//Metabolic pathways;Fructose and mannose metabolism
10670,0,15,2,7,10,4,37,0,0,0,0,0,RRAGA;Ras-related GTP binding A,GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus,GO:0034613//cellular protein localization;GO:0008219//cell death;GO:0006915//apoptotic process;GO:0071230//cellular response to amino acid stimulus;GO:0019048//modulation by virus of host morphology or physiology;GO:0032008//positive regulation of TOR signaling;GO:0045919//positive regulation of cytolysis,GO:0005525//GTP binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0051219//phosphoprotein binding,-
10671,0,0,0,1,20,0,0,0,0,0,0,0,DCTN6;dynactin 6,GO:0005813//centrosome;GO:0005869//dynactin complex;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore,GO:0007052//mitotic spindle organization;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0045502//dynein binding,K10428//Vasopressin-regulated water reabsorption
10672,0,25,0,0,87,19,21,0,44,0,8,0,"GNA13;guanine nucleotide binding protein (G protein), alpha 13",GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex;GO:0031526//brush border membrane;GO:0016020//membrane;GO:0042470//melanosome,GO:0001701//in utero embryonic development;GO:0030154//cell differentiation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001569//patterning of blood vessels;GO:0007266//Rho protein signal transduction;GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0031584//activation of phospholipase D activity;GO:0030334//regulation of cell migration;GO:0007596//blood coagulation;GO:0006184//GTP catabolic process;GO:0006928//cellular component movement;GO:0008360//regulation of cell shape;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0004871//signal transducer activity;GO:0031702//type 1 angiotensin receptor binding;GO:0003924//GTPase activity;GO:0031752//D5 dopamine receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K04639//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Long-term depression
10673,0,0,0,0,0,0,0,0,32,154,0,0,"TNFSF13B;tumor necrosis factor (ligand) superfamily, member 13b",GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0001782//B cell homeostasis;GO:0031296//B cell costimulation;GO:0002636//positive regulation of germinal center formation;GO:0006955//immune response;GO:0048305//immunoglobulin secretion;GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0030890//positive regulation of B cell proliferation;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation;GO:0008284//positive regulation of cell proliferation,GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005102//receptor binding,K05476//NF-kappa B signaling pathway;Rheumatoid arthritis;Cytokine-cytokine receptor interaction;Intestinal immune network for IgA production
10675,0,0,0,0,0,0,16,0,0,0,0,0,CSPG5;chondroitin sulfate proteoglycan 5 (neuroglycan C),GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0030660//Golgi-associated vesicle membrane;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0050804//regulation of synaptic transmission;GO:0046907//intracellular transport;GO:0040008//regulation of growth;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0031103//axon regeneration;GO:0007399//nervous system development,GO:0005515//protein binding;GO:0008083//growth factor activity,-
10677,114,27,26,53,35,0,37,0,2,0,35,0,AVIL;advillin,GO:0042995//cell projection;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0015629//actin cytoskeleton;GO:0030424//axon,GO:0060271//cilium morphogenesis;GO:0051693//actin filament capping;GO:0007010//cytoskeleton organization;GO:0007399//nervous system development;GO:0010976//positive regulation of neuron projection development,GO:0003779//actin binding,-
10678,0,0,0,0,0,0,14,0,23,0,3,0,"B3GNT2;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0007411//axon guidance;GO:0044267//cellular protein metabolic process;GO:0007608//sensory perception of smell,GO:0008378//galactosyltransferase activity,K00741//Glycosphingolipid biosynthesis - lacto and neolacto series;Glycosaminoglycan biosynthesis - keratan sulfate;Metabolic pathways
1068,0,0,0,0,0,5,0,0,25,0,0,0,"CETN1;centrin, EF-hand protein, 1",GO:0005814//centriole;GO:0005813//centrosome;GO:0032391//photoreceptor connecting cilium;GO:0000922//spindle pole,GO:0007067//mitotic nuclear division;GO:0006200//ATP catabolic process;GO:0034605//cellular response to heat,GO:0005524//ATP binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0008017//microtubule binding;GO:0003676//nucleic acid binding;GO:0032795//heterotrimeric G-protein binding;GO:0005509//calcium ion binding;GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding,K10840//Nucleotide excision repair
10681,0,1,0,1,0,3,45,1,46,0,0,0,"GNB5;guanine nucleotide binding protein (G protein), beta 5",GO:0005634//nucleus;GO:0005886//plasma membrane,"GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0006184//GTP catabolic process;GO:0007165//signal transduction;GO:1901386//negative regulation of voltage-gated calcium channel activity",GO:0051087//chaperone binding;GO:0003924//GTPase activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0031682//G-protein gamma-subunit binding,K04539//Alcoholism;Retrograde endocannabinoid signaling;Serotonergic synapse;Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Morphine addiction;Glutamatergic synapse
10682,0,0,1,0,0,0,1,0,10,0,0,0,EBP;emopamil binding protein (sterol isomerase),GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0006695//cholesterol biosynthetic process;GO:0001501//skeletal system development;GO:0030097//hemopoiesis;GO:0006855//drug transmembrane transport;GO:0044281//small molecule metabolic process;GO:0008203//cholesterol metabolic process;GO:0007165//signal transduction,GO:0000247//C-8 sterol isomerase activity;GO:0004888//transmembrane signaling receptor activity;GO:0047750//cholestenol delta-isomerase activity;GO:0004769//steroid delta-isomerase activity;GO:0015238//drug transmembrane transporter activity,K01824//Biosynthesis of secondary metabolites;Steroid biosynthesis;Metabolic pathways
10683,0,0,0,0,3,0,0,0,4,0,8,0,DLL3;delta-like 3 (Drosophila),GO:0016021//integral component of membrane,GO:0050768//negative regulation of neurogenesis;GO:0001501//skeletal system development;GO:0048339//paraxial mesoderm development;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0007386//compartment pattern specification,GO:0005112//Notch binding,K06051//Notch signaling pathway
10686,61,0,0,0,0,0,0,0,14,0,0,0,CLDN16;claudin 16,GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0015693//magnesium ion transport;GO:0006875//cellular metal ion homeostasis;GO:0007588//excretion,GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Cell adhesion molecules (CAMs);Tight junction
10687,0,0,0,0,0,0,0,0,22,0,0,0,PNMA2;paraneoplastic Ma antigen 2,GO:0005730//nucleolus,GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding,K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
1069,0,30,2,27,142,0,0,0,0,0,0,0,"CETN2;centrin, EF-hand protein, 2",GO:0005813//centrosome;GO:0032391//photoreceptor connecting cilium;GO:0005622//intracellular;GO:0071942//XPC complex;GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005829//cytosol,GO:0006289//nucleotide-excision repair;GO:0000278//mitotic cell cycle;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007283//spermatogenesis;GO:0032465//regulation of cytokinesis;GO:0007067//mitotic nuclear division;GO:0006200//ATP catabolic process,GO:0005509//calcium ion binding;GO:0032795//heterotrimeric G-protein binding;GO:0005515//protein binding;GO:0008026//ATP-dependent helicase activity;GO:0003676//nucleic acid binding;GO:0008017//microtubule binding;GO:0005524//ATP binding;GO:0031683//G-protein beta/gamma-subunit complex binding,K10840//Nucleotide excision repair
10690,0,0,0,0,0,0,0,46,39,0,0,0,"FUT9;fucosyltransferase 9 (alpha (1,3) fucosyltransferase)",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0042355//L-fucose catabolic process;GO:0007399//nervous system development;GO:0036065//fucosylation,GO:0046920//alpha-(1->3)-fucosyltransferase activity,K03663//Other types of O-glycan biosynthesis;Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways;Glycosphingolipid biosynthesis - globo series
10691,0,0,0,8,1,1,0,0,2,0,25,0,GMEB1;glucocorticoid modulatory element binding protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K11447//Transcriptional misregulation in cancer
10692,0,0,0,0,0,0,0,0,0,70,0,0,RRH;retinal pigment epithelium-derived rhodopsin homolog,GO:0005887//integral component of plasma membrane,GO:0007602//phototransduction;GO:0018298//protein-chromophore linkage;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007601//visual perception,GO:0009881//photoreceptor activity;GO:0004930//G-protein coupled receptor activity,-
10693,0,0,0,10,44,0,0,0,18,0,0,0,"CCT6B;chaperonin containing TCP1, subunit 6B (zeta 2)",GO:0005832//chaperonin-containing T-complex,GO:0006457//protein folding;GO:0051131//chaperone-mediated protein complex assembly;GO:0015031//protein transport;GO:0007283//spermatogenesis,GO:0051082//unfolded protein binding;GO:0008565//protein transporter activity;GO:0005524//ATP binding,-
10694,0,0,0,4,117,0,10,0,0,0,0,0,"CCT8;chaperonin containing TCP1, subunit 8 (theta)",GO:0045111//intermediate filament cytoskeleton;GO:0002199//zona pellucida receptor complex;GO:0005829//cytosol;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005832//chaperonin-containing T-complex;GO:0044297//cell body;GO:0005813//centrosome;GO:0016235//aggresome;GO:0005737//cytoplasm,GO:0044267//cellular protein metabolic process;GO:0006200//ATP catabolic process;GO:0007339//binding of sperm to zona pellucida;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding,"GO:0005524//ATP binding;GO:0042623//ATPase activity, coupled;GO:0051082//unfolded protein binding",-
10695,0,0,0,0,14,0,0,91,0,0,0,0,CNPY3;canopy FGF signaling regulator 3,GO:0005788//endoplasmic reticulum lumen,GO:0002224//toll-like receptor signaling pathway;GO:0045087//innate immune response,GO:0005102//receptor binding,"K00552//Glycine, serine and threonine metabolism"
10699,2,0,0,10,0,40,32,0,40,0,12,0,"CORIN;corin, serine peptidase",GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0008217//regulation of blood pressure;GO:0007565//female pregnancy;GO:0016486//peptide hormone processing;GO:0003050//regulation of systemic arterial blood pressure by atrial natriuretic peptide;GO:0035813//regulation of renal sodium excretion;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0070008//serine-type exopeptidase activity,-
107,101,23,0,3,64,10,57,60,144,10,25,47,ADCY1;adenylate cyclase 1 (brain),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0006112//energy reserve metabolic process;GO:0042752//regulation of circadian rhythm;GO:0007268//synaptic transmission;GO:0007623//circadian rhythm;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007616//long-term memory;GO:0006833//water transport;GO:0007165//signal transduction;GO:0034199//activation of protein kinase A activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0007202//activation of phospholipase C activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0010226//response to lithium ion;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007409//axonogenesis,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0008294//calcium- and calmodulin-responsive adenylate cyclase activity,K08041//Salivary secretion;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Calcium signaling pathway;HTLV-I infection;Cholinergic synapse;GABAergic synapse;Chagas disease (American trypanosomiasis);Bile secretion;Melanogenesis;Gastric acid secretion;Long-term potentiation;Progesterone-mediated oocyte maturation;Pancreatic secretion;Gap junction;Chemokine signaling pathway;GnRH signaling pathway;Purine metabolism;Amoebiasis;Oocyte meiosis;Morphine addiction;Vascular smooth muscle contraction;Glutamatergic synapse
1071,90,0,0,0,0,23,0,0,55,0,0,0,"CETP;cholesteryl ester transfer protein, plasma",GO:0034364//high-density lipoprotein particle;GO:0031982//vesicle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0043691//reverse cholesterol transport;GO:0034374//low-density lipoprotein particle remodeling;GO:0008203//cholesterol metabolic process;GO:0055088//lipid homeostasis;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0010874//regulation of cholesterol efflux;GO:0044281//small molecule metabolic process;GO:0042632//cholesterol homeostasis;GO:0006898//receptor-mediated endocytosis;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0015914//phospholipid transport;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0046470//phosphatidylcholine metabolic process;GO:0042157//lipoprotein metabolic process;GO:0055091//phospholipid homeostasis;GO:0070328//triglyceride homeostasis;GO:0034375//high-density lipoprotein particle remodeling;GO:0030301//cholesterol transport,GO:0005548//phospholipid transporter activity;GO:0017129//triglyceride binding;GO:0031210//phosphatidylcholine binding;GO:0005319//lipid transporter activity;GO:0017127//cholesterol transporter activity;GO:0008289//lipid binding;GO:0015485//cholesterol binding,K08761//PPAR signaling pathway;K05399//Toll-like receptor signaling pathway;Tuberculosis;Salmonella infection;NF-kappa B signaling pathway
10712,0,0,0,0,4,0,18,0,33,0,11,0,"FAM189B;family with sequence similarity 189, member B",GO:0016021//integral component of membrane,-,GO:0050699//WW domain binding;GO:0005515//protein binding,-
10713,0,0,0,0,29,20,28,1,22,0,0,0,USP39;ubiquitin specific peptidase 39,GO:0005681//spliceosomal complex,GO:0008380//RNA splicing;GO:0007049//cell cycle;GO:0006397//mRNA processing;GO:0051301//cell division;GO:0000245//spliceosomal complex assembly;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity;GO:0008270//zinc ion binding,K12847//Spliceosome
10714,0,22,0,0,0,0,0,0,27,1,0,0,"POLD3;polymerase (DNA-directed), delta 3, accessory subunit",GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0043625//delta DNA polymerase complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0000722//telomere maintenance via recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000278//mitotic cell cycle;GO:0000723//telomere maintenance;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000731//DNA synthesis involved in DNA repair;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006284//base-excision repair;GO:0006298//mismatch repair",GO:0005515//protein binding;GO:0003887//DNA-directed DNA polymerase activity,K03504//Nucleotide excision repair;HTLV-I infection;Mismatch repair;Pyrimidine metabolism;Homologous recombination;Base excision repair;DNA replication;Metabolic pathways;Purine metabolism
10715,0,0,0,0,0,0,0,1,7,51,1,0,CERS1;ceramide synthase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle,GO:0051974//negative regulation of telomerase activity;GO:0072721//cellular response to dithiothreitol;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0035690//cellular response to drug;GO:0036146//cellular response to mycotoxin;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0071492//cellular response to UV-A,GO:0050291//sphingosine N-acyltransferase activity,K04710//Metabolic pathways;Sphingolipid metabolism
10716,0,0,0,8,0,6,0,37,31,0,4,0,"TBR1;T-box, brain, 1",GO:0005634//nucleus,"GO:0007420//brain development;GO:0007411//axon guidance;GO:0010975//regulation of neuron projection development;GO:0010092//specification of organ identity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0030902//hindbrain development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding,-
10717,0,0,0,12,1,8,0,0,0,0,0,0,"AP4B1;adaptor-related protein complex 4, beta 1 subunit",GO:0005905//coated pit;GO:0005802//trans-Golgi network;GO:0030131//clathrin adaptor complex,GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport,GO:0008565//protein transporter activity;GO:0005215//transporter activity,K12401//Lysosome
10718,0,0,15,0,0,6,10,120,84,0,11,0,NRG3;neuregulin 3,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0035556//intracellular signal transduction;GO:0007389//pattern specification process;GO:0060596//mammary placode formation;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0001558//regulation of cell growth,GO:0008083//growth factor activity;GO:0030971//receptor tyrosine kinase binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity,K05457//ErbB signaling pathway
1072,0,75,0,42,124,0,0,0,16,1,32,0,CFL1;cofilin 1 (non-muscle),GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0016363//nuclear matrix;GO:0030864//cortical actin cytoskeleton;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0032587//ruffle membrane;GO:0031258//lamellipodium membrane;GO:0005925//focal adhesion,GO:0006606//protein import into nucleus;GO:0022604//regulation of cell morphogenesis;GO:0030836//positive regulation of actin filament depolymerization;GO:0007266//Rho protein signal transduction;GO:0030168//platelet activation;GO:0045792//negative regulation of cell size;GO:0030042//actin filament depolymerization;GO:0043200//response to amino acid;GO:0007596//blood coagulation;GO:0006468//protein phosphorylation;GO:0001755//neural crest cell migration;GO:0002576//platelet degranulation;GO:0000281//mitotic cytokinesis;GO:0030010//establishment of cell polarity;GO:0045087//innate immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0001842//neural fold formation;GO:0030036//actin cytoskeleton organization;GO:0007010//cytoskeleton organization;GO:0009615//response to virus;GO:0043066//negative regulation of apoptotic process;GO:0007411//axon guidance,GO:0003779//actin binding;GO:0005515//protein binding,K05765//Regulation of actin cytoskeleton;Axon guidance;Pertussis;Fc gamma R-mediated phagocytosis
10720,0,0,0,0,0,0,12,0,23,0,0,0,"UGT2B11;UDP glucuronosyltransferase 2 family, polypeptide B11",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0008210//estrogen metabolic process,GO:0015020//glucuronosyltransferase activity,K00699//Metabolic pathways;Pentose and glucuronate interconversions;Drug metabolism - cytochrome P450;Retinol metabolism;Bile secretion;Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Starch and sucrose metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis
10721,0,0,0,0,0,22,33,0,80,14,4,0,"POLQ;polymerase (DNA directed), theta",GO:0005654//nucleoplasm,GO:0006281//DNA repair;GO:0006261//DNA-dependent DNA replication;GO:0006200//ATP catabolic process,GO:0043142//single-stranded DNA-dependent ATPase activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0003684//damaged DNA binding;GO:0005524//ATP binding,-
10723,226,0,0,0,0,0,61,0,5,0,0,1,"SLC12A7;solute carrier family 12 (potassium/chloride transporter), member 7",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006810//transport;GO:0006811//ion transport;GO:1902476//chloride transmembrane transport;GO:0006813//potassium ion transport;GO:0055085//transmembrane transport;GO:0006821//chloride transport;GO:0006884//cell volume homeostasis,GO:0019901//protein kinase binding;GO:0015379//potassium:chloride symporter activity,K13627//Collecting duct acid secretion
10724,0,60,0,87,320,24,0,0,93,0,24,0,MGEA5;meningioma expressed antigen 5 (hyaluronidase),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane,GO:0007568//aging;GO:0032024//positive regulation of insulin secretion;GO:0016573//histone acetylation;GO:0006612//protein targeting to membrane;GO:0060051//negative regulation of protein glycosylation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0043243//positive regulation of protein complex disassembly;GO:0045862//positive regulation of proteolysis;GO:0031343//positive regulation of cell killing;GO:0048545//response to steroid hormone;GO:0051901//positive regulation of mitochondrial depolarization;GO:0006044//N-acetylglucosamine metabolic process;GO:0046060//dATP metabolic process;GO:0051054//positive regulation of DNA metabolic process;GO:0006516//glycoprotein catabolic process;GO:0060124//positive regulation of growth hormone secretion;GO:0046326//positive regulation of glucose import;GO:0010616//negative regulation of cardiac muscle adaptation;GO:0070265//necrotic cell death,GO:0004402//histone acetyltransferase activity;GO:0004415//hyalurononglucosaminidase activity,-
10725,0,6,0,39,140,29,34,0,89,0,13,0,"NFAT5;nuclear factor of activated T-cells 5, tonicity-responsive",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007588//excretion;GO:0070884//regulation of calcineurin-NFAT signaling cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0001816//cytokine production,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding,K04446//T cell receptor signaling pathway;Osteoclast differentiation;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;VEGF signaling pathway;Axon guidance;HTLV-I infection;B cell receptor signaling pathway
10726,0,41,0,11,48,0,0,1,16,0,7,0,NUDC;nudC nuclear distribution protein,GO:0005829//cytosol;GO:0005874//microtubule;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0008283//cell proliferation;GO:0007275//multicellular organismal development;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion
10728,0,86,0,228,590,11,1,0,6,0,22,526,PTGES3;prostaglandin E synthase 3 (cytosolic),"GO:0005697//telomerase holoenzyme complex;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000781//chromosome, telomeric region",GO:0060430//lung saccule development;GO:0006278//RNA-dependent DNA replication;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0019371//cyclooxygenase pathway;GO:0005978//glycogen biosynthetic process;GO:0019369//arachidonic acid metabolic process;GO:0008283//cell proliferation;GO:0001516//prostaglandin biosynthetic process;GO:0000723//telomere maintenance;GO:0043588//skin development;GO:0070389//chaperone cofactor-dependent protein refolding;GO:0042921//glucocorticoid receptor signaling pathway,GO:0003720//telomerase activity;GO:0051082//unfolded protein binding;GO:0050220//prostaglandin-E synthase activity;GO:0005515//protein binding,K15730//Metabolic pathways;Arachidonic acid metabolism
1073,46,0,0,0,66,0,0,0,17,0,0,0,CFL2;cofilin 2 (muscle),GO:0070062//extracellular vesicular exosome;GO:0015629//actin cytoskeleton;GO:0005615//extracellular space;GO:0016363//nuclear matrix;GO:0031674//I band,GO:0061001//regulation of dendritic spine morphogenesis;GO:0030042//actin filament depolymerization;GO:0046716//muscle cell cellular homeostasis;GO:0045214//sarcomere organization;GO:0030836//positive regulation of actin filament depolymerization,GO:0003779//actin binding;GO:0005515//protein binding,K05765//Regulation of actin cytoskeleton;Axon guidance;Fc gamma R-mediated phagocytosis;Pertussis
10730,0,154,2,111,271,0,0,1,25,0,0,0,YME1L1;YME1-like 1 ATPase,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008283//cell proliferation;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0007005//mitochondrion organization,GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,-
10732,0,0,0,0,0,0,0,1,0,0,0,0,TCFL5;transcription factor-like 5 (basic helix-loop-helix),GO:0005634//nucleus;GO:0001673//male germ cell nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0045595//regulation of cell differentiation;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
10733,0,0,0,0,0,23,22,58,0,250,0,0,PLK4;polo-like kinase 4,GO:0005730//nucleolus;GO:0098536//deuterosome;GO:0032154//cleavage furrow;GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome,GO:0007099//centriole replication;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0046601//positive regulation of centriole replication;GO:0006468//protein phosphorylation;GO:0098535//de novo centriole assembly;GO:0060707//trophoblast giant cell differentiation,GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
10734,169,182,183,279,427,30,0,235,36,101,534,0,STAG3;stromal antigen 3,"GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0000800//lateral element;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0001673//male germ cell nucleus;GO:0034991//nuclear meiotic cohesin complex;GO:0000802//transverse filament;GO:0030893//meiotic cohesin complex",GO:0007130//synaptonemal complex assembly;GO:0007059//chromosome segregation,-,K13055//Oocyte meiosis
10735,0,39,0,77,141,50,0,0,17,0,10,0,STAG2;stromal antigen 2,"GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005694//chromosome;GO:0005654//nucleoplasm;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0000785//chromatin;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus",GO:0007067//mitotic nuclear division;GO:0019827//stem cell maintenance;GO:0032876//negative regulation of DNA endoreduplication;GO:0000278//mitotic cell cycle;GO:0007062//sister chromatid cohesion;GO:0007126//meiotic nuclear division,GO:0005515//protein binding;GO:0003682//chromatin binding,K06671//Meiosis - yeast;Cell cycle - yeast;Cell cycle
10736,0,0,0,0,0,4,0,0,0,0,0,0,SIX2;SIX homeobox 2,GO:0005634//nucleus,GO:0048701//embryonic cranial skeleton morphogenesis;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0048557//embryonic digestive tract morphogenesis;GO:0001822//kidney development;GO:0009653//anatomical structure morphogenesis;GO:0008283//cell proliferation;GO:0002062//chondrocyte differentiation;GO:1902732//positive regulation of chondrocyte proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042474//middle ear morphogenesis;GO:0016477//cell migration;GO:0006606//protein import into nucleus;GO:0007501//mesodermal cell fate specification;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0072028//nephron morphogenesis,GO:0032403//protein complex binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K15614//Transcriptional misregulation in cancer
10738,0,38,48,59,1,0,0,23,28,0,66,0,RFPL3;ret finger protein-like 3,-,-,GO:0008270//zinc ion binding,-
10739,12,1,2,27,37,29,11,108,15,0,0,56,RFPL2;ret finger protein-like 2,-,-,GO:0008270//zinc ion binding,-
10740,1,144,2,34,83,0,0,0,58,0,59,0,RFPL1S;RFPL1 antisense RNA 1,-,-,-,-
10741,0,30,0,5,104,0,9,0,0,0,0,0,RBBP9;retinoblastoma binding protein 9,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0042127//regulation of cell proliferation;GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
10742,0,0,0,1,0,12,0,0,47,0,2,0,RAI2;retinoic acid induced 2,-,GO:0009790//embryo development,GO:0005515//protein binding,-
10743,94,11,0,0,1,14,38,23,8,199,0,0,RAI1;retinoic acid induced 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0040015//negative regulation of multicellular organism growth;GO:0032922//circadian regulation of gene expression;GO:0001501//skeletal system development",GO:0035326//enhancer binding;GO:0008270//zinc ion binding,K09188//Lysine degradation;K09186//Transcriptional misregulation in cancer;Lysine degradation
10745,0,0,0,0,13,0,0,0,12,0,22,0,PHTF1;putative homeodomain transcription factor 1,GO:0005634//nucleus;GO:0005801//cis-Golgi network;GO:0005783//endoplasmic reticulum,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10746,109,26,1,43,194,18,10,52,54,0,0,0,MAP3K2;mitogen-activated protein kinase kinase kinase 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0071260//cellular response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0007257//activation of JUN kinase activity;GO:0000186//activation of MAPKK activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000187//activation of MAPK activity",GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity,K04420//GnRH signaling pathway;MAPK signaling pathway;Gap junction
10747,119,0,0,11,21,0,29,0,40,0,7,0,MASP2;mannan-binding lectin serine peptidase 2,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0001867//complement activation, lectin pathway;GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0006956//complement activation",GO:0008233//peptidase activity;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0001855//complement component C4b binding,K03993//Complement and coagulation cascades;Staphylococcus aureus infection
10749,0,38,13,23,115,19,42,33,15,150,0,0,KIF1C;kinesin family member 1C,GO:0005874//microtubule;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0005871//kinesin complex,"GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0016192//vesicle-mediated transport;GO:0007018//microtubule-based movement;GO:0008219//cell death",GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0008017//microtubule binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
1075,0,0,0,0,0,0,14,0,25,0,0,0,CTSC;cathepsin C,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005764//lysosome,GO:0006915//apoptotic process;GO:0001913//T cell mediated cytotoxicity;GO:0006955//immune response;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0006508//proteolysis;GO:0010033//response to organic substance;GO:0007568//aging;GO:1903052//positive regulation of proteolysis involved in cellular protein catabolic process,GO:0051087//chaperone binding;GO:0008234//cysteine-type peptidase activity;GO:0042802//identical protein binding;GO:0031404//chloride ion binding;GO:0019902//phosphatase binding;GO:0043621//protein self-association;GO:0004252//serine-type endopeptidase activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0005515//protein binding,K01275//Lysosome
10750,0,0,0,0,0,0,0,0,10,0,0,0,GRAP;GRB2-related adaptor protein,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0007267//cell-cell signaling;GO:0009967//positive regulation of signal transduction;GO:0007265//Ras protein signal transduction,GO:0005070//SH3/SH2 adaptor activity,K04364//Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Renal cell carcinoma;ErbB signaling pathway;Insulin signaling pathway;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Alcoholism;Prostate cancer;Neurotrophin signaling pathway;Hepatitis C;Osteoclast differentiation;MAPK signaling pathway - fly;Non-small cell lung cancer;Endometrial cancer;Dorso-ventral axis formation;Focal adhesion;Glioma;Jak-STAT signaling pathway;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway
10752,0,54,0,1,0,59,43,59,112,0,2,0,CHL1;cell adhesion molecule L1-like,GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0005578//proteinaceous extracellular matrix,GO:0008344//adult locomotory behavior;GO:0043524//negative regulation of neuron apoptotic process;GO:0007165//signal transduction;GO:0001764//neuron migration;GO:0050890//cognition;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0035640//exploration behavior;GO:0031103//axon regeneration,GO:0002020//protease binding,-
10753,0,0,0,0,0,0,10,50,37,0,4,0,CAPN9;calpain 9,GO:0005737//cytoplasm,GO:0007586//digestion;GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
10755,0,0,0,1,9,0,0,0,30,129,12,0,"GIPC1;GIPC PDZ domain containing family, member 1",GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0008021//synaptic vesicle;GO:0070062//extracellular vesicular exosome;GO:0043198//dendritic shaft;GO:0005903//brush border;GO:0012506//vesicle membrane;GO:0030139//endocytic vesicle;GO:0005829//cytosol,GO:0014047//glutamate secretion;GO:0048167//regulation of synaptic plasticity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0031647//regulation of protein stability;GO:0007268//synaptic transmission;GO:0006605//protein targeting;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032467//positive regulation of cytokinesis;GO:0043542//endothelial cell migration,GO:0005515//protein binding;GO:0017022//myosin binding;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding;GO:0030165//PDZ domain binding;GO:0003779//actin binding,-
10758,0,2,0,15,6,0,15,0,33,70,6,1,TRAF3IP2;TRAF3 interacting protein 2,-,GO:0048305//immunoglobulin secretion;GO:0006959//humoral immune response;GO:0001783//B cell apoptotic process;GO:0035556//intracellular signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer
10761,0,0,0,0,0,0,0,0,2,0,0,0,PLAC1;placenta-specific 1,GO:0005576//extracellular region,GO:0001890//placenta development;GO:0090214//spongiotrophoblast layer developmental growth,-,-
10762,0,28,1,25,43,13,18,0,29,0,8,0,NUP50;nucleoporin 50kDa,GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0046907//intracellular transport;GO:0044281//small molecule metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0015758//glucose transport,GO:0005515//protein binding,K14295//RNA transport
10763,0,0,0,0,0,16,1,0,35,0,10,0,NES;nestin,GO:0005882//intermediate filament;GO:0045111//intermediate filament cytoskeleton;GO:0005737//cytoplasm,GO:2000179//positive regulation of neural precursor cell proliferation;GO:0048858//cell projection morphogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0072089//stem cell proliferation;GO:0031076//embryonic camera-type eye development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007420//brain development;GO:0007417//central nervous system development;GO:0032091//negative regulation of protein binding;GO:0030844//positive regulation of intermediate filament depolymerization;GO:0043086//negative regulation of catalytic activity,GO:0019215//intermediate filament binding;GO:0005198//structural molecule activity,-
10765,0,38,24,104,118,0,61,1,77,0,0,230,KDM5B;lysine (K)-specific demethylase 5B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034721//histone H3-K4 demethylation, trimethyl-H3-K4-specific;GO:0055114//oxidation-reduction process;GO:0034720//histone H3-K4 demethylation","GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0034648//histone demethylase activity (H3-dimethyl-K4 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0003714//transcription corepressor activity;GO:0034647//histone demethylase activity (H3-trimethyl-K4 specific)",-
10766,0,8,1,0,33,9,37,5,36,50,1,62,"TOB2;transducer of ERBB2, 2",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0010468//regulation of gene expression;GO:0007292//female gamete generation;GO:0045671//negative regulation of osteoclast differentiation;GO:0045778//positive regulation of ossification;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding;GO:0042809//vitamin D receptor binding,K14443//RNA degradation
10767,0,22,0,37,13,59,18,61,60,64,0,0,HBS1L;HBS1-like translational GTPase,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0006414//translational elongation;GO:0007165//signal transduction;GO:0006412//translation;GO:0006184//GTP catabolic process,GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity,K14416//Legionellosis;mRNA surveillance pathway
10768,10,63,1,35,225,17,20,0,60,0,1,243,AHCYL1;adenosylhomocysteinase-like 1,GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0006611//protein export from nucleus;GO:0010765//positive regulation of sodium ion transport;GO:0006730//one-carbon metabolic process;GO:0032412//regulation of ion transmembrane transporter activity;GO:0031440//regulation of mRNA 3'-end processing;GO:0044070//regulation of anion transport;GO:0006378//mRNA polyadenylation,GO:0005515//protein binding;GO:0004013//adenosylhomocysteinase activity,K01251//Metabolic pathways;Cysteine and methionine metabolism
10769,137,0,0,0,22,0,24,23,14,0,0,1,PLK2;polo-like kinase 2,GO:0005813//centrosome;GO:0005814//centriole;GO:0005622//intracellular;GO:0030425//dendrite,GO:0060291//long-term synaptic potentiation;GO:0048167//regulation of synaptic plasticity;GO:0043066//negative regulation of apoptotic process;GO:0060292//long term synaptic depression;GO:0007052//mitotic spindle organization;GO:0006468//protein phosphorylation;GO:0007093//mitotic cell cycle checkpoint;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007265//Ras protein signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032486//Rap protein signal transduction;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0046599//regulation of centriole replication;GO:0007613//memory,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0004674//protein serine/threonine kinase activity,-
10771,0,163,0,98,238,31,21,3,34,7,0,285,"ZMYND11;zinc finger, MYND-type containing 11",GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005694//chromosome,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046329//negative regulation of JNK cascade;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0034243//regulation of transcription elongation from RNA polymerase II promoter;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0016568//chromatin modification;GO:0007049//cell cycle;GO:0016032//viral process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling",GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding;GO:0003677//DNA binding,-
10772,0,0,0,0,1,0,0,0,14,0,0,0,SRSF10;serine/arginine-rich splicing factor 10,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck,"GO:0006406//mRNA export from nucleus;GO:0006376//mRNA splice site selection;GO:0016482//cytoplasmic transport;GO:0006355//regulation of transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0048025//negative regulation of mRNA splicing, via spliceosome",GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0051082//unfolded protein binding,K12900//Spliceosome
10773,0,1,0,21,78,20,0,0,13,1,0,0,ZBTB6;zinc finger and BTB domain containing 6,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10775,0,4,0,1,11,22,0,0,19,0,0,0,"POP4;processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)",GO:0005655//nucleolar ribonuclease P complex;GO:0000172//ribonuclease MRP complex,"GO:0006379//mRNA cleavage;GO:0008033//tRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0006364//rRNA processing",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0004526//ribonuclease P activity;GO:0000171//ribonuclease MRP activity,K03538//Ribosome biogenesis in eukaryotes;RNA transport
10776,0,48,1,93,282,1,1,1,18,0,0,0,"ARPP19;cAMP-regulated phosphoprotein, 19kDa",GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0045722//positive regulation of gluconeogenesis;GO:0050790//regulation of catalytic activity;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043086//negative regulation of catalytic activity;GO:0046326//positive regulation of glucose import,GO:0005102//receptor binding;GO:0051721//protein phosphatase 2A binding;GO:0004864//protein phosphatase inhibitor activity;GO:0015459//potassium channel regulator activity;GO:0019212//phosphatase inhibitor activity;GO:0008601//protein phosphatase type 2A regulator activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K11447//Transcriptional misregulation in cancer
10777,0,0,0,0,0,10,0,0,42,0,0,0,"ARPP21;cAMP-regulated phosphoprotein, 21kDa",GO:0005737//cytoplasm,GO:0034605//cellular response to heat,GO:0005516//calmodulin binding;GO:0003676//nucleic acid binding,K02360//Dorso-ventral axis formation
10778,0,38,0,36,152,0,0,0,20,0,9,0,ZNF271;zinc finger protein 271,-,-,-,-
10780,0,0,0,10,48,14,0,0,30,0,14,0,ZNF234;zinc finger protein 234,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10781,94,0,0,8,39,5,0,0,46,0,0,0,ZNF266;zinc finger protein 266,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10782,0,0,0,4,14,0,0,0,8,0,1,0,ZNF274;zinc finger protein 274,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity,K12458//Neurotrophin signaling pathway
10783,0,62,0,1,84,0,36,39,36,0,3,160,NEK6;NIMA-related kinase 6,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0016607//nuclear speck;GO:0005829//cytosol,GO:0007077//mitotic nuclear envelope disassembly;GO:0000910//cytokinesis;GO:0051225//spindle assembly;GO:0046777//protein autophosphorylation;GO:0007067//mitotic nuclear division;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031572//G2 DNA damage checkpoint;GO:2000772//regulation of cellular senescence,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004871//signal transducer activity;GO:0004674//protein serine/threonine kinase activity;GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,-
10785,0,0,0,9,5,0,1,0,32,85,0,0,WDR4;WD repeat domain 4,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030488//tRNA methylation;GO:0006400//tRNA modification;GO:0036265//RNA (guanine-N7)-methylation,GO:0008176//tRNA (guanine-N7-)-methyltransferase activity;GO:0005515//protein binding,-
10786,0,0,0,0,0,20,0,0,43,0,0,0,"SLC17A3;solute carrier family 17 (organic anion transporter), member 3",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0015849//organic acid transport;GO:0015893//drug transport;GO:0015747//urate transport;GO:0035435//phosphate ion transmembrane transport;GO:0006814//sodium ion transport;GO:0015711//organic anion transport;GO:0035725//sodium ion transmembrane transport;GO:1901998//toxin transport;GO:0044070//regulation of anion transport;GO:0015760//glucose-6-phosphate transport;GO:0055085//transmembrane transport;GO:0006855//drug transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006817//phosphate ion transport;GO:0046415//urate metabolic process,GO:0005436//sodium:phosphate symporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity;GO:0015238//drug transmembrane transporter activity;GO:0008308//voltage-gated anion channel activity;GO:0015143//urate transmembrane transporter activity;GO:0019534//toxin transporter activity,-
10787,0,42,0,41,96,23,1,33,102,0,7,0,NCKAP1;NCK-associated protein 1,GO:0031209//SCAR complex;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0070062//extracellular vesicular exosome,"GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0001756//somitogenesis;GO:0016601//Rac protein signal transduction;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0045087//innate immune response;GO:0032880//regulation of protein localization;GO:0001701//in utero embryonic development;GO:0045175//basal protein localization;GO:0050821//protein stabilization;GO:0007417//central nervous system development;GO:0007492//endoderm development;GO:0048340//paraxial mesoderm morphogenesis;GO:0008078//mesodermal cell migration;GO:0048570//notochord morphogenesis;GO:0001843//neural tube closure;GO:0045176//apical protein localization;GO:0035050//embryonic heart tube development;GO:0048617//embryonic foregut morphogenesis;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0010172//embryonic body morphogenesis;GO:0030032//lamellipodium assembly;GO:0010592//positive regulation of lamellipodium assembly;GO:0006915//apoptotic process",GO:0005515//protein binding;GO:0032403//protein complex binding;GO:0048365//Rac GTPase binding,K05750//Regulation of actin cytoskeleton
10788,0,0,21,55,72,0,0,3,2,0,2,0,IQGAP2;IQ motif containing GTPase activating protein 2,GO:0070062//extracellular vesicular exosome;GO:0015629//actin cytoskeleton;GO:0005902//microvillus;GO:0005874//microtubule,GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0032320//positive regulation of Ras GTPase activity,"GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005099//Ras GTPase activator activity;GO:0005095//GTPase inhibitor activity",K05767//Regulation of actin cytoskeleton;Adherens junction
10793,0,0,0,0,0,33,0,3,0,0,0,0,ZNF273;zinc finger protein 273,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
10794,0,1,0,25,107,2,38,0,45,0,19,0,ZNF460;zinc finger protein 460,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
10795,90,0,1,5,40,4,22,28,31,0,0,0,ZNF268;zinc finger protein 268,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045732//positive regulation of protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0090073//positive regulation of protein homodimerization activity;GO:0008284//positive regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0030335//positive regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071157//negative regulation of cell cycle arrest;GO:0006351//transcription, DNA-templated;GO:0007346//regulation of mitotic cell cycle;GO:0071356//cellular response to tumor necrosis factor;GO:0046022//positive regulation of transcription from RNA polymerase II promoter during mitosis;GO:0043497//regulation of protein heterodimerization activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0043065//positive regulation of apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0045597//positive regulation of cell differentiation",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
10797,0,2,0,11,30,15,14,21,20,0,0,0,"MTHFD2;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase",GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0006730//one-carbon metabolic process;GO:0055114//oxidation-reduction process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0046653//tetrahydrofolate metabolic process,GO:0000287//magnesium ion binding;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0042301//phosphate ion binding,K13403//Metabolic pathways;One carbon pool by folate
10799,28,0,1,0,37,0,0,0,14,215,29,0,RPP40;ribonuclease P/MRP 40kDa subunit,GO:0005655//nucleolar ribonuclease P complex;GO:0005634//nucleus,"GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0008033//tRNA processing",GO:0004526//ribonuclease P activity,K14530//Ribosome biogenesis in eukaryotes;RNA transport
108,0,0,0,0,0,11,1,0,82,0,0,0,ADCY2;adenylate cyclase 2 (brain),GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045121//membrane raft;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0006112//energy reserve metabolic process;GO:0034199//activation of protein kinase A activity;GO:0007165//signal transduction;GO:0006833//water transport;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0008294//calcium- and calmodulin-responsive adenylate cyclase activity;GO:0008179//adenylate cyclase binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0046982//protein heterodimerization activity,K08042//Retrograde endocannabinoid signaling;Dilated cardiomyopathy;Calcium signaling pathway;Salivary secretion;GABAergic synapse;HTLV-I infection;Cholinergic synapse;Gastric acid secretion;Melanogenesis;Bile secretion;Pancreatic secretion;Progesterone-mediated oocyte maturation;Gap junction;GnRH signaling pathway;Chemokine signaling pathway;Purine metabolism;Glutamatergic synapse;Morphine addiction;Oocyte meiosis;Vascular smooth muscle contraction
1080,60,0,0,0,0,60,0,0,116,196,0,0,"CFTR;cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)",GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030659//cytoplasmic vesicle membrane;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0043234//protein complex;GO:0031901//early endosome membrane;GO:0016323//basolateral plasma membrane;GO:0034707//chloride channel complex;GO:0031205//endoplasmic reticulum Sec complex,GO:1902476//chloride transmembrane transport;GO:0015705//iodide transport;GO:0032870//cellular response to hormone stimulus;GO:0030321//transepithelial chloride transport;GO:0006200//ATP catabolic process;GO:0030301//cholesterol transport;GO:0006833//water transport;GO:0045909//positive regulation of vasodilation;GO:0030324//lung development;GO:0034097//response to cytokine;GO:0042311//vasodilation;GO:0071320//cellular response to cAMP;GO:0006810//transport;GO:0006695//cholesterol biosynthetic process;GO:0015701//bicarbonate transport;GO:0043627//response to estrogen;GO:0043434//response to peptide hormone;GO:0060081//membrane hyperpolarization;GO:0042493//response to drug;GO:0007585//respiratory gaseous exchange;GO:1902943//positive regulation of voltage-gated chloride channel activity;GO:0048240//sperm capacitation;GO:0051454//intracellular pH elevation;GO:0055085//transmembrane transport,GO:0005224//ATP-binding and phosphorylation-dependent chloride channel activity;GO:0005524//ATP binding;GO:0005254//chloride channel activity;GO:0005260//channel-conductance-controlling ATPase activity;GO:0019899//enzyme binding;GO:0019869//chloride channel inhibitor activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0015108//chloride transmembrane transporter activity,K05031//ABC transporters;Bile secretion;Vibrio cholerae infection;Gastric acid secretion;Pancreatic secretion
10800,0,0,52,0,0,37,60,0,34,222,0,0,CYSLTR1;cysteinyl leukotriene receptor 1,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007585//respiratory gaseous exchange;GO:0006952//defense response;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0005515//protein binding;GO:0004974//leukotriene receptor activity,K04322//Calcium signaling pathway;Neuroactive ligand-receptor interaction
10801,100,1,1,15,5,19,19,2,21,0,13,0,SEPT9;septin 9,GO:0015629//actin cytoskeleton;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process;GO:0051301//cell division;GO:0007049//cell cycle;GO:0051291//protein heterooligomerization,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K04557//Parkinson's disease
10802,0,32,0,37,96,0,11,0,57,0,0,0,SEC24A;SEC24 family member A,GO:0030127//COPII vesicle coat;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0048208//COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0043687//post-translational protein modification;GO:2000189//positive regulation of cholesterol homeostasis;GO:0050714//positive regulation of protein secretion;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0008270//zinc ion binding,K14007//Protein processing in endoplasmic reticulum
10803,0,0,0,0,0,0,0,0,15,0,12,0,CCR9;chemokine (C-C motif) receptor 9,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface,GO:0007186//G-protein coupled receptor signaling pathway;GO:0006968//cellular defense response;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070098//chemokine-mediated signaling pathway,GO:0004950//chemokine receptor activity;GO:0016493//C-C chemokine receptor activity,K04184//Chemokine signaling pathway;Cytokine-cytokine receptor interaction;Intestinal immune network for IgA production
10804,0,0,0,0,0,5,0,30,4,0,0,0,"GJB6;gap junction protein, beta 6, 30kDa",GO:0005922//connexon complex;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0007154//cell communication;GO:0007605//sensory perception of sound;GO:0006915//apoptotic process;GO:0042471//ear morphogenesis;GO:0048839//inner ear development;GO:0008285//negative regulation of cell proliferation,-,-
10806,0,0,1,58,71,0,0,0,24,0,0,0,SDCCAG8;serologically defined colon cancer antigen 8,GO:0005911//cell-cell junction;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005814//centriole,GO:0030010//establishment of cell polarity;GO:0035148//tube formation;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0005515//protein binding,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
10807,0,0,0,2,19,0,0,38,0,0,5,0,SDCCAG3;serologically defined colon cancer antigen 3,GO:0005737//cytoplasm,-,-,-
10808,0,38,1,9,158,0,23,0,56,0,13,0,HSPH1;heat shock 105kDa/110kDa protein 1,GO:0005737//cytoplasm;GO:0071682//endocytic vesicle lumen;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0051135//positive regulation of NK T cell activation;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0006986//response to unfolded protein,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0043014//alpha-tubulin binding,K09485//Protein processing in endoplasmic reticulum
10809,0,48,2,0,15,7,26,2,0,3,0,0,STARD10;StAR-related lipid transfer (START) domain containing 10,GO:0005829//cytosol;GO:0016020//membrane;GO:0046581//intercellular canaliculus;GO:0005902//microvillus,GO:0032782//bile acid secretion;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway,GO:0008289//lipid binding;GO:0005515//protein binding,K01067//Pyruvate metabolism
1081,0,0,0,0,0,0,0,0,18,0,14,0,"CGA;glycoprotein hormones, alpha polypeptide",GO:0005576//extracellular region,GO:0008406//gonad development;GO:0046621//negative regulation of organ growth;GO:0044267//cellular protein metabolic process;GO:0030335//positive regulation of cell migration;GO:0016486//peptide hormone processing;GO:0030878//thyroid gland development;GO:0008284//positive regulation of cell proliferation;GO:0032870//cellular response to hormone stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046884//follicle-stimulating hormone secretion;GO:0007267//cell-cell signaling;GO:0048589//developmental growth;GO:0032275//luteinizing hormone secretion;GO:0006590//thyroid hormone generation;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0005179//hormone activity,K08522//Neuroactive ligand-receptor interaction;GnRH signaling pathway;Autoimmune thyroid disease
10810,101,0,0,10,33,11,12,0,48,0,2,0,"WASF3;WAS protein family, member 3",GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0008360//regulation of cell shape;GO:0031643//positive regulation of myelination;GO:0030032//lamellipodium assembly;GO:0007010//cytoskeleton organization;GO:0014003//oligodendrocyte development;GO:0030041//actin filament polymerization;GO:0006461//protein complex assembly,GO:0003779//actin binding,K06083//Adherens junction;Fc gamma R-mediated phagocytosis
10811,63,0,2,0,0,2,0,0,23,0,0,0,NOXA1;NADPH oxidase activator 1,GO:0043020//NADPH oxidase complex;GO:0005737//cytoplasm,GO:0043085//positive regulation of catalytic activity;GO:0060263//regulation of respiratory burst;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0006801//superoxide metabolic process,GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0048365//Rac GTPase binding;GO:0019899//enzyme binding;GO:0016176//superoxide-generating NADPH oxidase activator activity,K08010//Phagosome;Osteoclast differentiation;Leishmaniasis;Leukocyte transendothelial migration
10813,112,0,0,11,0,0,6,0,52,0,2,0,"UTP14A;UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)",GO:0032040//small-subunit processome;GO:0005730//nucleolus,GO:0006364//rRNA processing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14567//Ribosome biogenesis in eukaryotes
10814,35,0,0,0,0,0,0,0,21,0,2,0,CPLX2;complexin 2,GO:0043025//neuronal cell body;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex;GO:0005829//cytosol;GO:0042629//mast cell granule;GO:0030425//dendrite;GO:0045202//synapse,GO:0017157//regulation of exocytosis;GO:0031915//positive regulation of synaptic plasticity;GO:0030154//cell differentiation;GO:0006904//vesicle docking involved in exocytosis;GO:0043303//mast cell degranulation;GO:0016079//synaptic vesicle exocytosis;GO:0007399//nervous system development,GO:0017075//syntaxin-1 binding;GO:0048306//calcium-dependent protein binding,K15294//Synaptic vesicle cycle
10815,0,0,5,13,0,0,0,109,18,0,42,0,CPLX1;complexin 1,GO:0005829//cytosol;GO:0030425//dendrite;GO:0045202//synapse;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex;GO:0043025//neuronal cell body,GO:0016079//synaptic vesicle exocytosis;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0014047//glutamate secretion;GO:0030073//insulin secretion;GO:0017157//regulation of exocytosis;GO:0006887//exocytosis,GO:0017075//syntaxin-1 binding;GO:0005326//neurotransmitter transporter activity,K15294//Synaptic vesicle cycle
10817,0,0,0,0,0,12,4,0,18,0,0,0,FRS3;fibroblast growth factor receptor substrate 3,GO:0005886//plasma membrane,GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0005104//fibroblast growth factor receptor binding;GO:0005158//insulin receptor binding,K12461//Neurotrophin signaling pathway;K08328//Phototransduction;Olfactory transduction
10818,137,0,0,44,60,1,0,0,37,1,0,0,FRS2;fibroblast growth factor receptor substrate 2,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,"GO:0050678//regulation of epithelial cell proliferation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0070307//lens fiber cell development;GO:0008286//insulin receptor signaling pathway;GO:0007405//neuroblast proliferation;GO:0042981//regulation of apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0003281//ventricular septum development;GO:0008595//anterior/posterior axis specification, embryo;GO:0001702//gastrulation with mouth forming second;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0000186//activation of MAPKK activity;GO:0000187//activation of MAPK activity;GO:0030900//forebrain development;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0001759//organ induction;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0046619//optic placode formation involved in camera-type eye formation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis",GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005158//insulin receptor binding;GO:0019211//phosphatase activator activity;GO:0005515//protein binding;GO:0005104//fibroblast growth factor receptor binding;GO:0005168//neurotrophin TRKA receptor binding,K12461//Neurotrophin signaling pathway
10819,0,0,0,0,0,53,0,0,0,0,0,0,"OR7E14P;olfactory receptor, family 7, subfamily E, member 14 pseudogene",-,-,-,K04257//Olfactory transduction
1082,0,0,0,0,0,1,0,0,0,0,0,0,"CGB;chorionic gonadotropin, beta polypeptide",GO:0005576//extracellular region,GO:0007292//female gamete generation;GO:0016486//peptide hormone processing;GO:0006915//apoptotic process;GO:0007267//cell-cell signaling;GO:0044267//cellular protein metabolic process;GO:0007165//signal transduction,GO:0005179//hormone activity,-
10821,0,0,0,0,0,0,0,0,12,0,0,0,"OR7E12P;olfactory receptor, family 7, subfamily E, member 12 pseudogene",-,-,-,K04257//Olfactory transduction
10825,0,71,0,13,24,42,75,0,30,0,0,0,NEU3;sialidase 3 (membrane sialidase),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006689//ganglioside catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0006665//sphingolipid metabolic process,GO:0052796//exo-alpha-(2->8)-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity,K12357//Other glycan degradation;Sphingolipid metabolism
10826,119,0,0,0,0,0,0,0,0,0,8,0,FAXDC2;fatty acid hydroxylase domain containing 2,GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process,GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity,K07750//Metabolic pathways;Steroid biosynthesis
10827,0,0,0,14,27,25,22,0,18,0,0,0,"FAM114A2;family with sequence similarity 114, member A2",-,-,GO:0017076//purine nucleotide binding,-
10838,133,39,0,0,3,0,73,0,42,44,0,0,ZNF275;zinc finger protein 275,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1084,0,0,0,0,0,0,0,0,31,0,4,0,CEACAM3;carcinoembryonic antigen-related cell adhesion molecule 3,GO:0016021//integral component of membrane,-,-,-
10840,0,0,16,0,36,0,26,82,9,130,12,0,"ALDH1L1;aldehyde dehydrogenase 1 family, member L1",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0032259//methylation;GO:0009058//biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0055114//oxidation-reduction process;GO:0009258//10-formyltetrahydrofolate catabolic process,"GO:0016742//hydroxymethyl-, formyl- and related transferase activity;GO:0008168//methyltransferase activity;GO:0003824//catalytic activity;GO:0016155//formyltetrahydrofolate dehydrogenase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor",K00289//One carbon pool by folate
10841,0,0,0,0,0,33,4,66,25,0,0,0,FTCD;formimidoyltransferase cyclodeaminase,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005814//centriole;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0007010//cytoskeleton organization;GO:0006760//folic acid-containing compound metabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0019557//histidine catabolic process to glutamate and formate;GO:0034641//cellular nitrogen compound metabolic process;GO:0006548//histidine catabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0044281//small molecule metabolic process,GO:0030409//glutamate formimidoyltransferase activity;GO:0030412//formimidoyltetrahydrofolate cyclodeaminase activity;GO:0005542//folic acid binding,K13990//One carbon pool by folate;Histidine metabolism;Metabolic pathways
10842,0,0,0,0,0,24,0,0,24,0,0,0,"PPP1R17;protein phosphatase 1, regulatory subunit 17",-,GO:0035556//intracellular signal transduction;GO:0007417//central nervous system development;GO:0010921//regulation of phosphatase activity;GO:0043086//negative regulation of catalytic activity,GO:0004865//protein serine/threonine phosphatase inhibitor activity,K08067//Long-term depression
10844,187,284,97,245,500,0,21,569,196,195,497,0,"TUBGCP2;tubulin, gamma complex associated protein 2",GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005881//cytoplasmic microtubule,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007020//microtubule nucleation;GO:0006461//protein complex assembly,GO:0005515//protein binding,K01769//Purine metabolism
10845,53,0,0,17,37,26,0,0,35,0,0,0,CLPX;caseinolytic mitochondrial matrix peptidase chaperone subunit,GO:0005743//mitochondrial inner membrane;GO:0009368//endopeptidase Clp complex;GO:0009841//mitochondrial endopeptidase Clp complex;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006457//protein folding;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006200//ATP catabolic process;GO:0010952//positive regulation of peptidase activity,GO:0016887//ATPase activity;GO:0051082//unfolded protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016504//peptidase activator activity;GO:0004176//ATP-dependent peptidase activity,K03544//Cell cycle - Caulobacter
10846,0,0,0,60,132,4,86,0,94,37,1,0,PDE10A;phosphodiesterase 10A,GO:0005829//cytosol,GO:0010738//regulation of protein kinase A signaling;GO:0007596//blood coagulation;GO:0046069//cGMP catabolic process;GO:0007165//signal transduction;GO:0043949//regulation of cAMP-mediated signaling;GO:0006198//cAMP catabolic process,"GO:0046872//metal ion binding;GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity",K01120//Morphine addiction;Purine metabolism
10847,102,30,1,53,41,77,0,53,74,0,18,0,SRCAP;Snf2-related CREBBP activator protein,GO:0005794//Golgi apparatus;GO:0043234//protein complex;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0016573//histone acetylation;GO:0006351//transcription, DNA-templated",GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0004386//helicase activity;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding,-
10848,101,0,0,0,0,0,18,0,9,0,0,0,"PPP1R13L;protein phosphatase 1, regulatory subunit 13 like",GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0035264//multicellular organism growth;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031076//embryonic camera-type eye development;GO:0003215//cardiac right ventricle morphogenesis;GO:0042633//hair cycle;GO:0003229//ventricular cardiac muscle tissue development;GO:0060048//cardiac muscle contraction;GO:0048871//multicellular organismal homeostasis;GO:0009791//post-embryonic development",GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0008134//transcription factor binding;GO:0003714//transcription corepressor activity,K06270//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Long-term potentiation;Focal adhesion
10849,1,750,357,508,1166,0,137,1027,279,403,1719,1280,"CD3EAP;CD3e molecule, epsilon associated protein",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000120//RNA polymerase I transcription factor complex;GO:0005730//nucleolus;GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0005736//DNA-directed RNA polymerase I complex,GO:0009303//rRNA transcription;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0044822//poly(A) RNA binding;GO:0003899//DNA-directed RNA polymerase activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
10855,0,0,0,0,0,4,34,0,33,0,0,0,HPSE;heparanase,GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane;GO:0045121//membrane raft;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0010575//positive regulation vascular endothelial growth factor production;GO:0007160//cell-matrix adhesion;GO:0030200//heparan sulfate proteoglycan catabolic process;GO:0033690//positive regulation of osteoblast proliferation;GO:0006027//glycosaminoglycan catabolic process;GO:0051797//regulation of hair follicle development;GO:0030194//positive regulation of blood coagulation;GO:0051798//positive regulation of hair follicle development;GO:0005975//carbohydrate metabolic process;GO:0006029//proteoglycan metabolic process;GO:0061042//vascular wound healing;GO:0051897//positive regulation of protein kinase B signaling;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process,GO:0046983//protein dimerization activity;GO:0004566//beta-glucuronidase activity;GO:0045545//syndecan binding;GO:0030305//heparanase activity;GO:0005515//protein binding,K07964//Glycosaminoglycan degradation;Metabolic pathways
10856,0,0,1,1,2,0,13,0,15,0,0,0,RUVBL2;RuvB-like AAA ATPase 2,GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0031011//Ino80 complex;GO:0005737//cytoplasm;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005622//intracellular;GO:0005719//nuclear euchromatin;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0016363//nuclear matrix;GO:0000812//Swr1 complex,"GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0006310//DNA recombination;GO:0043967//histone H4 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071733//transcriptional activation by promoter-enhancer looping;GO:0071899//negative regulation of estrogen receptor binding;GO:0043968//histone H2A acetylation;GO:0006338//chromatin remodeling;GO:0006325//chromatin organization;GO:0032508//DNA duplex unwinding;GO:0071169//establishment of protein localization to chromatin;GO:0035066//positive regulation of histone acetylation;GO:0034644//cellular response to UV;GO:0071392//cellular response to estradiol stimulus;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0006457//protein folding",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0031490//chromatin DNA binding;GO:0042802//identical protein binding;GO:0003678//DNA helicase activity;GO:0016887//ATPase activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0043141//ATP-dependent 5'-3' DNA helicase activity;GO:0051082//unfolded protein binding,-
10857,80,0,0,0,13,0,0,0,0,0,0,0,PGRMC1;progesterone receptor membrane component 1,GO:0005789//endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0007411//axon guidance,GO:0005515//protein binding;GO:0005496//steroid binding;GO:0020037//heme binding,-
10858,0,0,0,0,0,16,0,0,0,0,0,0,"CYP46A1;cytochrome P450, family 46, subfamily A, polypeptide 1",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0016125//sterol metabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006707//cholesterol catabolic process;GO:0055114//oxidation-reduction process;GO:0007399//nervous system development;GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process,GO:0008395//steroid hydroxylase activity;GO:0020037//heme binding;GO:0033781//cholesterol 24-hydroxylase activity;GO:0005506//iron ion binding,K07440//Primary bile acid biosynthesis
10859,70,0,0,0,0,0,31,46,35,0,4,0,"LILRB1;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1",GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,"GO:0010628//positive regulation of gene expression;GO:0035548//negative regulation of interferon-beta secretion;GO:0009615//response to virus;GO:0042536//negative regulation of tumor necrosis factor biosynthetic process;GO:2001186//negative regulation of CD8-positive, alpha-beta T cell activation;GO:0032689//negative regulation of interferon-gamma production;GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0046636//negative regulation of alpha-beta T cell activation;GO:0032609//interferon-gamma production;GO:0002230//positive regulation of defense response to virus by host;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0031623//receptor internalization;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0072643//interferon-gamma secretion;GO:0071222//cellular response to lipopolysaccharide;GO:0002740//negative regulation of cytokine secretion involved in immune response;GO:0050776//regulation of immune response;GO:2001199//negative regulation of dendritic cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0051926//negative regulation of calcium ion transport;GO:2001183//negative regulation of interleukin-12 secretion;GO:2001202//negative regulation of transforming growth factor-beta secretion;GO:0002309//T cell proliferation involved in immune response;GO:2001180//negative regulation of interleukin-10 secretion;GO:0097028//dendritic cell differentiation;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:2001193//positive regulation of gamma-delta T cell activation involved in immune response;GO:2001189//negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:2001205//negative regulation of osteoclast development;GO:0043065//positive regulation of apoptotic process;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0014063//negative regulation of serotonin secretion;GO:0045806//negative regulation of endocytosis;GO:0007165//signal transduction;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0045919//positive regulation of cytolysis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus",GO:0042803//protein homodimerization activity;GO:0032393//MHC class I receptor activity;GO:0030107//HLA-A specific inhibitory MHC class I receptor activity;GO:0008157//protein phosphatase 1 binding;GO:0030109//HLA-B specific inhibitory MHC class I receptor activity;GO:0042169//SH2 domain binding;GO:0042288//MHC class I protein binding,K06512//Osteoclast differentiation;B cell receptor signaling pathway
10861,0,0,0,4,32,21,0,86,30,0,83,1,"SLC26A1;solute carrier family 26 (anion exchanger), member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008272//sulfate transport;GO:0006805//xenobiotic metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006821//chloride transport;GO:1902476//chloride transmembrane transport;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0019532//oxalate transport;GO:1902358//sulfate transmembrane transport,GO:0015116//sulfate transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0008271//secondary active sulfate transmembrane transporter activity,-
10863,1,0,0,0,16,29,64,0,70,0,5,0,ADAM28;ADAM metallopeptidase domain 28,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0007283//spermatogenesis,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
10864,0,0,0,0,0,0,34,0,14,0,0,0,"SLC22A7;solute carrier family 22 (organic anion transporter), member 7",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane,GO:0015711//organic anion transport;GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:0035634//response to stilbenoid,GO:0015347//sodium-independent organic anion transmembrane transporter activity,K08204//Bile secretion
10865,87,0,0,9,0,0,0,0,21,0,0,0,ARID5A;AT rich interactive domain 5A (MRF1-like),GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0002062//chondrocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035066//positive regulation of histone acetylation",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0003677//DNA binding,-
10866,0,0,0,0,2,0,2,0,0,0,0,0,HCP5;HLA complex P5 (non-protein coding),-,GO:0006952//defense response,-,-
10867,0,0,0,0,0,13,21,0,0,36,0,0,TSPAN9;tetraspanin 9,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0097197//tetraspanin-enriched microdomain,-,-,-
10868,0,0,0,1,10,0,18,67,75,125,36,0,USP20;ubiquitin specific peptidase 20,GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0071108//protein K48-linked deubiquitination;GO:0006897//endocytosis;GO:0070536//protein K63-linked deubiquitination;GO:0016579//protein deubiquitination,GO:0001664//G-protein coupled receptor binding;GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
10869,67,0,2,3,8,43,0,86,26,1,22,177,USP19;ubiquitin specific peptidase 19,GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0016579//protein deubiquitination;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0090068//positive regulation of cell cycle process;GO:0014732//skeletal muscle atrophy;GO:1900037//regulation of cellular response to hypoxia;GO:0034976//response to endoplasmic reticulum stress;GO:0031647//regulation of protein stability;GO:0048642//negative regulation of skeletal muscle tissue development,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004843//ubiquitin-specific protease activity,K06243//ECM-receptor interaction;Toxoplasmosis;Pathways in cancer;Focal adhesion;Small cell lung cancer;Amoebiasis
1087,23,0,0,0,0,10,16,0,43,0,0,0,CEACAM7;carcinoembryonic antigen-related cell adhesion molecule 7,GO:0031225//anchored component of membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
10870,0,0,0,0,0,0,0,0,5,0,0,0,HCST;hematopoietic cell signal transducer,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0050776//regulation of immune response,GO:0005102//receptor binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005515//protein binding,K07988//Natural killer cell mediated cytotoxicity
10871,4,0,0,0,0,0,0,0,40,0,0,0,CD300C;CD300c molecule,GO:0005887//integral component of plasma membrane,GO:0002376//immune system process;GO:0007165//signal transduction;GO:0006968//cellular defense response,GO:0004888//transmembrane signaling receptor activity,-
10873,0,71,0,0,0,0,24,0,7,0,41,0,"ME3;malic enzyme 3, NADP(+)-dependent, mitochondrial",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0006108//malate metabolic process;GO:0009060//aerobic respiration;GO:0006090//pyruvate metabolic process;GO:0072592//oxygen metabolic process,GO:0004470//malic enzyme activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0051287//NAD binding;GO:0008948//oxaloacetate decarboxylase activity;GO:0048037//cofactor binding;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0046872//metal ion binding,K00029//PPAR signaling pathway;Microbial metabolism in diverse environments;Pyruvate metabolism;Metabolic pathways;Carbon fixation in photosynthetic organisms
10875,0,0,0,0,0,0,0,0,1,0,0,0,FGL2;fibrinogen-like 2,GO:0070062//extracellular vesicular exosome;GO:0005577//fibrinogen complex,-,-,-
10876,0,0,0,0,0,0,0,0,1,0,0,0,EDDM3A;epididymal protein 3A,GO:0005615//extracellular space,GO:0007321//sperm displacement,-,-
10877,92,0,0,0,0,0,1,1,27,0,0,0,CFHR4;complement factor H-related 4,GO:0005576//extracellular region,GO:0006869//lipid transport,GO:0005319//lipid transporter activity,K04004//Staphylococcus aureus infection;Complement and coagulation cascades
10878,0,0,0,0,0,0,0,0,19,0,0,0,CFHR3;complement factor H-related 3,GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005615//extracellular space,-,-,K04004//Staphylococcus aureus infection;Complement and coagulation cascades
1088,0,0,0,0,0,0,0,75,26,0,0,0,CEACAM8;carcinoembryonic antigen-related cell adhesion molecule 8,GO:0005887//integral component of plasma membrane;GO:0031225//anchored component of membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006955//immune response,-,-
10880,0,0,0,0,0,0,20,0,6,0,0,0,ACTL7B;actin-like 7B,GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm,-,GO:0005200//structural constituent of cytoskeleton,K05692//Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Adherens junction;Phototransduction - fly;Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion
10881,0,0,0,0,0,0,0,0,62,3,7,0,ACTL7A;actin-like 7A,GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0043234//protein complex;GO:0031514//motile cilium;GO:0005794//Golgi apparatus,-,GO:0005200//structural constituent of cytoskeleton,K05692//Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction
10882,0,0,0,0,0,0,0,0,6,0,0,0,"C1QL1;complement component 1, q subcomponent-like 1",GO:0005737//cytoplasm;GO:0005581//collagen trimer;GO:0005576//extracellular region,GO:0007626//locomotory behavior,-,K07296//Type II diabetes mellitus;Adipocytokine signaling pathway;PPAR signaling pathway
10884,0,12,0,0,32,0,0,0,0,0,10,0,MRPS30;mitochondrial ribosomal protein S30,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0006412//translation;GO:0006915//apoptotic process,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
10885,0,0,0,12,16,0,41,0,44,0,0,0,WDR3;WD repeat domain 3,GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,K14556//Ribosome biogenesis in eukaryotes
10886,0,0,0,0,0,0,0,0,2,0,0,0,NPFFR2;neuropeptide FF receptor 2,GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0005887//integral component of plasma membrane,GO:0009582//detection of abiotic stimulus;GO:0007218//neuropeptide signaling pathway;GO:0045761//regulation of adenylate cyclase activity;GO:2000479//regulation of cAMP-dependent protein kinase activity;GO:0043408//regulation of MAPK cascade;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0008188//neuropeptide receptor activity;GO:0031628//opioid receptor binding,K08375//Neuroactive ligand-receptor interaction
10887,0,0,0,0,22,0,0,60,0,0,6,0,PROKR1;prokineticin receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway;GO:0043066//negative regulation of apoptotic process,GO:0004983//neuropeptide Y receptor activity,-
10888,0,0,0,0,0,0,0,0,45,0,0,0,GPR83;G protein-coupled receptor 83,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0051384//response to glucocorticoid;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004983//neuropeptide Y receptor activity,K04210//Neuroactive ligand-receptor interaction
1089,0,0,0,0,0,0,0,46,29,0,0,0,CEACAM4;carcinoembryonic antigen-related cell adhesion molecule 4,GO:0016020//membrane;GO:0005887//integral component of plasma membrane,-,-,-
10890,0,90,0,70,244,19,0,0,22,0,0,0,"RAB10;RAB10, member RAS oncogene family",GO:0005802//trans-Golgi network;GO:0000145//exocyst;GO:0030659//cytoplasmic vesicle membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0055037//recycling endosome;GO:0032593//insulin-responsive compartment;GO:0005789//endoplasmic reticulum membrane;GO:0071782//endoplasmic reticulum tubular network;GO:0055038//recycling endosome membrane;GO:0072372//primary cilium;GO:0005925//focal adhesion,GO:0043001//Golgi to plasma membrane protein transport;GO:0030859//polarized epithelial cell differentiation;GO:0016197//endosomal transport;GO:0061024//membrane organization;GO:0006893//Golgi to plasma membrane transport;GO:0007409//axonogenesis;GO:0045200//establishment of neuroblast polarity;GO:0071786//endoplasmic reticulum tubular network organization;GO:0061467//basolateral protein localization;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:0072659//protein localization to plasma membrane;GO:0019882//antigen processing and presentation;GO:0032869//cellular response to insulin stimulus;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0031489//myosin V binding;GO:0019003//GDP binding,-
10891,0,0,0,0,0,5,0,69,6,65,0,0,"PPARGC1A;peroxisome proliferator-activated receptor gamma, coactivator 1 alpha","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005829//cytosol","GO:0006355//regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0045893//positive regulation of transcription, DNA-templated;GO:2001171//positive regulation of ATP biosynthetic process;GO:2000507//positive regulation of energy homeostasis;GO:0019395//fatty acid oxidation;GO:0008380//RNA splicing;GO:0071873//response to norepinephrine;GO:0050821//protein stabilization;GO:0001659//temperature homeostasis;GO:1901857//positive regulation of cellular respiration;GO:0032922//circadian regulation of gene expression;GO:0071250//cellular response to nitrite;GO:0042594//response to starvation;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0030521//androgen receptor signaling pathway;GO:0001678//cellular glucose homeostasis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006012//galactose metabolic process;GO:1901863//positive regulation of muscle tissue development;GO:0045722//positive regulation of gluconeogenesis;GO:0046321//positive regulation of fatty acid oxidation;GO:0010822//positive regulation of mitochondrion organization;GO:0050873//brown fat cell differentiation;GO:0006461//protein complex assembly;GO:0006397//mRNA processing;GO:1901215//negative regulation of neuron death;GO:0006094//gluconeogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045333//cellular respiration;GO:2000272//negative regulation of receptor activity;GO:0009409//response to cold;GO:0035066//positive regulation of histone acetylation;GO:0007005//mitochondrion organization;GO:0051552//flavone metabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0034599//cellular response to oxidative stress;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0097067//cellular response to thyroid hormone stimulus;GO:0022904//respiratory electron transport chain;GO:0043524//negative regulation of neuron apoptotic process;GO:0007586//digestion;GO:0071871//response to epinephrine;GO:0043201//response to leucine;GO:0036273//response to statin;GO:0071398//cellular response to fatty acid;GO:0045820//negative regulation of glycolytic process;GO:0008209//androgen metabolic process;GO:1901860//positive regulation of mitochondrial DNA metabolic process;GO:0014850//response to muscle activity;GO:0042752//regulation of circadian rhythm;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity",GO:0008134//transcription factor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0050681//androgen receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding,K07202//Huntington's disease;Insulin signaling pathway;Adipocytokine signaling pathway
10892,0,1,1,49,132,17,21,95,24,89,1,0,MALT1;mucosa associated lymphoid tissue lymphoma translocation gene 1,GO:0005829//cytosol;GO:0032449//CBM complex;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0005737//cytoplasm,GO:0009620//response to fungus;GO:0042981//regulation of apoptotic process;GO:0031398//positive regulation of protein ubiquitination;GO:0051168//nuclear export;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0050852//T cell receptor signaling pathway;GO:0006508//proteolysis;GO:0032743//positive regulation of interleukin-2 production;GO:0006952//defense response;GO:0050870//positive regulation of T cell activation;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0042098//T cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002726//positive regulation of T cell cytokine production;GO:0001923//B-1 B cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination,GO:0004871//signal transducer activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0043621//protein self-association;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0002020//protease binding;GO:0019209//kinase activator activity,K07369//B cell receptor signaling pathway;Tuberculosis;NF-kappa B signaling pathway;T cell receptor signaling pathway
10893,0,1192,377,850,1176,13,165,1305,578,312,2493,697,MMP24;matrix metallopeptidase 24 (membrane-inserted),GO:0032588//trans-Golgi network membrane;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane,GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0043085//positive regulation of catalytic activity;GO:0098609//cell-cell adhesion;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0010001//glial cell differentiation;GO:0006508//proteolysis;GO:0097150//neuronal stem cell maintenance,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity,-
10894,0,0,0,0,0,7,0,0,51,0,4,0,LYVE1;lymphatic vessel endothelial hyaluronan receptor 1,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030214//hyaluronan catabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0009611//response to wounding;GO:0030203//glycosaminoglycan metabolic process;GO:0030212//hyaluronan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006928//cellular component movement;GO:0009653//anatomical structure morphogenesis;GO:0007160//cell-matrix adhesion;GO:0006810//transport,GO:0005540//hyaluronic acid binding;GO:0004888//transmembrane signaling receptor activity;GO:0004872//receptor activity,K06256//Hematopoietic cell lineage;ECM-receptor interaction;Shigellosis;Epstein-Barr virus infection
10896,21,0,0,0,0,0,36,0,0,0,0,0,OCLM;oculomedin,-,GO:0007601//visual perception,-,-
10898,0,0,0,0,0,0,0,0,0,169,0,0,"CPSF4;cleavage and polyadenylation specific factor 4, 30kDa",GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex,GO:0019054//modulation by virus of host process;GO:0019048//modulation by virus of host morphology or physiology;GO:0019058//viral life cycle;GO:0006397//mRNA processing;GO:0046778//modification by virus of host mRNA processing,GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,K14404//Influenza A;mRNA surveillance pathway
10899,0,122,170,302,383,0,0,44,7,0,247,0,JTB;jumping translocation breakpoint,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005819//spindle;GO:0030496//midbody;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0042127//regulation of cell proliferation;GO:0000910//cytokinesis;GO:0008637//apoptotic mitochondrial changes;GO:0045860//positive regulation of protein kinase activity;GO:0007067//mitotic nuclear division,GO:0019901//protein kinase binding,-
109,68,60,36,84,179,17,0,96,45,0,142,0,ADCY3;adenylate cyclase 3,GO:0005929//cilium;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0006112//energy reserve metabolic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034199//activation of protein kinase A activity;GO:0006833//water transport;GO:0007165//signal transduction;GO:0007608//sensory perception of smell;GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0045087//innate immune response;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0004016//adenylate cyclase activity;GO:0046872//metal ion binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding,K08043//Purine metabolism;Oocyte meiosis;Morphine addiction;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Glutamatergic synapse;Progesterone-mediated oocyte maturation;Pancreatic secretion;Gap junction;Chemokine signaling pathway;GnRH signaling pathway;Bile secretion;Vibrio cholerae infection;Melanogenesis;Gastric acid secretion;Salivary secretion;Dilated cardiomyopathy;Olfactory transduction;Calcium signaling pathway;Retrograde endocannabinoid signaling;HTLV-I infection;Cholinergic synapse;GABAergic synapse
10900,0,0,0,5,0,0,0,0,105,91,6,312,RUNDC3A;RUN domain containing 3A,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0031284//positive regulation of guanylate cyclase activity;GO:0030828//positive regulation of cGMP biosynthetic process,GO:0030250//guanylate cyclase activator activity;GO:0005083//small GTPase regulator activity;GO:0051428//peptide hormone receptor binding,K12482//Endocytosis
10901,0,427,168,333,528,0,0,236,20,0,245,0,DHRS4;dehydrogenase/reductase (SDR family) member 4,GO:0031965//nuclear membrane;GO:0005777//peroxisome;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0005778//peroxisomal membrane;GO:0070062//extracellular vesicular exosome,GO:0042180//cellular ketone metabolic process;GO:0006066//alcohol metabolic process;GO:0051262//protein tetramerization;GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process,"GO:0005102//receptor binding;GO:0004090//carbonyl reductase (NADPH) activity;GO:0018455//alcohol dehydrogenase [NAD(P)+] activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0000253//3-keto sterol reductase activity",K11147//Metabolic pathways;Peroxisome;Retinol metabolism
10902,0,0,0,0,0,0,1,0,25,0,0,0,BRD8;bromodomain containing 8,GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0000812//Swr1 complex;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0043967//histone H4 acetylation;GO:0030522//intracellular receptor signaling pathway;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043968//histone H2A acetylation;GO:0006325//chromatin organization",GO:0004887//thyroid hormone receptor activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
10903,0,0,0,0,14,0,33,0,0,0,3,0,MTMR11;myotubularin related protein 11,-,GO:0016311//dephosphorylation,GO:0016791//phosphatase activity,K01112//Fructose and mannose metabolism
10904,102,14,0,0,0,0,15,0,3,0,5,0,BLCAP;bladder cancer associated protein,GO:0016021//integral component of membrane,GO:0030262//apoptotic nuclear changes;GO:0007049//cell cycle,GO:0005515//protein binding,-
10905,0,81,0,72,164,32,24,0,54,137,19,0,"MAN1A2;mannosidase, alpha, class 1A, member 2",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0043687//post-translational protein modification;GO:0006491//N-glycan processing;GO:0007585//respiratory gaseous exchange;GO:0048286//lung alveolus development;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,"GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",K01230//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis;Protein processing in endoplasmic reticulum
10906,128,32,0,33,18,0,27,0,0,0,4,0,TRAFD1;TRAF-type zinc finger domain containing 1,-,GO:0045824//negative regulation of innate immune response;GO:0034097//response to cytokine,GO:0005515//protein binding;GO:0046872//metal ion binding,-
10907,0,0,0,1,15,0,0,0,33,0,0,0,TXNL4A;thioredoxin-like 4A,GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0007067//mitotic nuclear division;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0000245//spliceosomal complex assembly",GO:0005515//protein binding,K12859//Spliceosome
10908,106,0,0,0,0,0,0,56,28,0,13,0,PNPLA6;patatin-like phospholipase domain containing 6,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0001525//angiogenesis;GO:0009887//organ morphogenesis;GO:0016042//lipid catabolic process;GO:0008219//cell death;GO:0046470//phosphatidylcholine metabolic process,GO:0004622//lysophospholipase activity,K14676//Glycerophospholipid metabolism
10910,77,8,0,8,55,2,0,0,47,0,0,0,"SUGT1;SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)",GO:0005829//cytosol;GO:0000776//kinetochore;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045087//innate immune response;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0007067//mitotic nuclear division",GO:0005515//protein binding,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction
10911,0,0,0,0,0,18,0,0,0,0,0,0,UTS2;urotensin 2,GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0045777//positive regulation of blood pressure;GO:0048146//positive regulation of fibroblast proliferation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0033574//response to testosterone;GO:0003105//negative regulation of glomerular filtration;GO:0045766//positive regulation of angiogenesis;GO:0010459//negative regulation of heart rate;GO:0010460//positive regulation of heart rate;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042493//response to drug;GO:0007268//synaptic transmission;GO:0046676//negative regulation of insulin secretion;GO:0006936//muscle contraction;GO:0001666//response to hypoxia;GO:0008217//regulation of blood pressure;GO:0045597//positive regulation of cell differentiation;GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep;GO:0035811//negative regulation of urine volume;GO:0045776//negative regulation of blood pressure;GO:0010763//positive regulation of fibroblast migration;GO:0045909//positive regulation of vasodilation;GO:0032224//positive regulation of synaptic transmission, cholinergic;GO:0035814//negative regulation of renal sodium excretion",GO:0005179//hormone activity;GO:0005102//receptor binding,-
10912,0,0,0,6,22,0,0,0,0,0,9,0,"GADD45G;growth arrest and DNA-damage-inducible, gamma",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051726//regulation of cell cycle;GO:0006950//response to stress;GO:0043065//positive regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:0046330//positive regulation of JNK cascade;GO:0000186//activation of MAPKK activity;GO:0006915//apoptotic process;GO:0006469//negative regulation of protein kinase activity;GO:0030154//cell differentiation;GO:0000185//activation of MAPKKK activity;GO:1900745//positive regulation of p38MAPK cascade,GO:0005515//protein binding,K04402//Cell cycle;p53 signaling pathway;NF-kappa B signaling pathway;MAPK signaling pathway
10913,69,0,0,0,0,0,17,0,44,0,0,64,EDAR;ectodysplasin A receptor,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0045177//apical part of cell,GO:0042475//odontogenesis of dentin-containing tooth;GO:0030154//cell differentiation;GO:0001942//hair follicle development;GO:0043473//pigmentation;GO:0007165//signal transduction;GO:0008544//epidermis development;GO:0006915//apoptotic process;GO:0060662//salivary gland cavitation;GO:0042346//positive regulation of NF-kappaB import into nucleus,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004872//receptor activity,K05162//Cytokine-cytokine receptor interaction
10914,0,49,2,77,261,32,0,0,29,19,22,0,PAPOLA;poly(A) polymerase alpha,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0031124//mRNA 3'-end processing;GO:0043631//RNA polyadenylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome",GO:0030145//manganese ion binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0000287//magnesium ion binding,K14376//mRNA surveillance pathway
10915,0,25,0,6,36,0,34,0,62,0,0,0,TCERG1;transcription elongation regulator 1,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0070064//proline-rich region binding;GO:0044822//poly(A) RNA binding;GO:0001106//RNA polymerase II transcription corepressor activity,K12824//Spliceosome
10916,65,65,1,4,130,0,0,0,38,0,11,0,"MAGED2;melanoma antigen family D, 2",GO:0016020//membrane,-,-,K12464//Neurotrophin signaling pathway
10917,0,0,0,0,0,0,0,14,7,0,0,0,BTNL3;butyrophilin-like 3,GO:0016021//integral component of membrane,-,-,-
10920,4,13,0,5,18,0,0,0,15,0,13,0,COPS8;COP9 signalosome subunit 8,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0008180//COP9 signalosome,GO:0010388//cullin deneddylation;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0008285//negative regulation of cell proliferation,-,-
10921,0,30,0,12,57,0,1,0,0,14,20,0,"RNPS1;RNA binding protein S1, serine-rich domain",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0035145//exon-exon junction complex;GO:0061574//ASAP complex;GO:0005829//cytosol;GO:0016607//nuclear speck,"GO:0000398//mRNA splicing, via spliceosome;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0043065//positive regulation of apoptotic process;GO:0006406//mRNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031124//mRNA 3'-end processing;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding,K14325//mRNA surveillance pathway;RNA transport
10922,0,0,0,0,1,0,4,0,0,0,16,0,FASTK;Fas-activated serine/threonine kinase,GO:0005739//mitochondrion,GO:0043484//regulation of RNA splicing;GO:0097190//apoptotic signaling pathway;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0033867//Fas-activated serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity,-
10923,0,45,0,17,138,0,2,0,61,0,0,0,SUB1;SUB1 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003697//single-stranded DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
10924,0,43,0,31,24,16,0,80,56,0,64,0,"SMPDL3A;sphingomyelin phosphodiesterase, acid-like 3A",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0006685//sphingomyelin catabolic process,"GO:0005515//protein binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0004767//sphingomyelin phosphodiesterase activity",-
10926,0,1,0,22,58,13,13,0,16,0,62,319,DBF4;DBF4 zinc finger,GO:0005654//nucleoplasm,GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0043085//positive regulation of catalytic activity;GO:0000082//G1/S transition of mitotic cell cycle,GO:0003676//nucleic acid binding;GO:0008047//enzyme activator activity;GO:0008270//zinc ion binding,K06629//Cell cycle
10927,0,38,1,84,213,0,0,0,73,0,0,0,SPIN1;spindlin 1,GO:0005634//nucleus;GO:0005819//spindle;GO:0005730//nucleolus,GO:0016568//chromatin modification;GO:0007275//multicellular organismal development;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0009303//rRNA transcription;GO:0007126//meiotic nuclear division;GO:0007276//gamete generation,GO:0035064//methylated histone binding;GO:0005515//protein binding,-
10928,3,20,0,43,306,69,0,65,49,0,4,0,RALBP1;ralA binding protein 1,GO:0016020//membrane;GO:0005829//cytosol,GO:0006810//transport;GO:0006935//chemotaxis;GO:0032855//positive regulation of Rac GTPase activity;GO:0043087//regulation of GTPase activity;GO:0043089//positive regulation of Cdc42 GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007165//signal transduction;GO:0006200//ATP catabolic process,"GO:0030675//Rac GTPase activator activity;GO:0016887//ATPase activity;GO:0043492//ATPase activity, coupled to movement of substances;GO:0005515//protein binding;GO:0048365//Rac GTPase binding;GO:0005096//GTPase activator activity;GO:0017160//Ral GTPase binding",K08773//Pancreatic cancer;Pathways in cancer
10929,0,29,0,1,102,0,0,0,0,0,15,0,SRSF8;serine/arginine-rich splicing factor 8,GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K12891//Herpes simplex infection;Spliceosome
10930,0,0,0,12,0,11,0,38,0,0,0,0,"APOBEC2;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2",-,GO:0006397//mRNA processing;GO:0080111//DNA demethylation;GO:0016556//mRNA modification;GO:0009972//cytidine deamination,GO:0004126//cytidine deaminase activity;GO:0003723//RNA binding;GO:0008270//zinc ion binding,K01500//Atrazine degradation;Microbial metabolism in diverse environments
10933,7,62,24,119,360,8,20,0,30,0,8,0,MORF4L1;mortality factor 4 like 1,GO:0035267//NuA4 histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex,"GO:0043967//histone H4 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0016575//histone deacetylation;GO:0043968//histone H2A acetylation;GO:0006325//chromatin organization;GO:0000724//double-strand break repair via homologous recombination",GO:0047485//protein N-terminus binding;GO:0003682//chromatin binding;GO:0005515//protein binding,-
10936,0,0,0,0,0,0,0,0,23,0,0,61,GPR75;G protein-coupled receptor 75,GO:0005887//integral component of plasma membrane,GO:0070098//chemokine-mediated signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:1901214//regulation of neuron death,GO:0004930//G-protein coupled receptor activity;GO:0016493//C-C chemokine receptor activity,-
10938,0,49,27,14,14,11,11,136,31,0,16,1,EHD1;EH-domain containing 1,GO:0048471//perinuclear region of cytoplasm;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0055038//recycling endosome membrane;GO:0031095//platelet dense tubular network membrane;GO:0010008//endosome membrane;GO:0005811//lipid particle;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0042632//cholesterol homeostasis;GO:0007596//blood coagulation;GO:0006184//GTP catabolic process;GO:0006897//endocytosis;GO:0034383//low-density lipoprotein particle clearance;GO:2001137//positive regulation of endocytic recycling;GO:0032456//endocytic recycling;GO:1990090//cellular response to nerve growth factor stimulus;GO:0051260//protein homooligomerization;GO:0010886//positive regulation of cholesterol storage;GO:1901741//positive regulation of myoblast fusion;GO:0031175//neuron projection development;GO:0006886//intracellular protein transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,K12483//Endocytosis
10939,0,164,0,41,137,0,25,134,17,0,121,0,AFG3L2;AFG3-like AAA ATPase 2,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0042407//cristae formation;GO:0060013//righting reflex;GO:0042552//myelination;GO:0021675//nerve development;GO:0007528//neuromuscular junction development;GO:0007409//axonogenesis;GO:0048747//muscle fiber development;GO:0008053//mitochondrial fusion;GO:0008219//cell death;GO:0034982//mitochondrial protein processing;GO:0040014//regulation of multicellular organism growth,GO:0008270//zinc ion binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004222//metalloendopeptidase activity,-
10940,0,0,0,7,0,16,0,0,40,98,22,0,"POP1;processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)",GO:0005615//extracellular space;GO:0005655//nucleolar ribonuclease P complex;GO:0000172//ribonuclease MRP complex,"GO:0016078//tRNA catabolic process;GO:0001682//tRNA 5'-leader removal;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0090501//RNA phosphodiester bond hydrolysis",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004526//ribonuclease P activity;GO:0000171//ribonuclease MRP activity,K01164//RNA transport;Ribosome biogenesis in eukaryotes
10942,0,0,0,0,0,0,32,0,0,0,0,0,"PRSS21;protease, serine, 21 (testisin)",GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0006508//proteolysis;GO:0007283//spermatogenesis,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity,-
10943,0,0,0,0,0,0,0,0,9,0,10,0,MSL3;male-specific lethal 3 homolog (Drosophila),GO:0005634//nucleus;GO:0072487//MSL complex;GO:0005654//nucleoplasm,"GO:0006366//transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0043984//histone H4-K16 acetylation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0035064//methylated histone binding,-
10944,104,44,0,85,199,5,43,48,59,0,13,0,C11orf58;chromosome 11 open reading frame 58,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
10945,0,0,0,16,2,9,0,0,0,0,0,0,KDELR1;KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1,GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0030663//COPI-coated vesicle membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:0006621//protein retention in ER lumen,GO:0005046//KDEL sequence binding,K10949//Vibrio cholerae infection
10946,0,54,0,9,64,0,41,0,10,0,27,0,"SF3A3;splicing factor 3a, subunit 3, 60kDa",GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0000389//mRNA 3'-splice site recognition;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions",GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12827//Spliceosome
10947,0,0,0,4,13,1,14,0,25,0,19,0,"AP3M2;adaptor-related protein complex 3, mu 2 subunit",GO:0030659//cytoplasmic vesicle membrane;GO:0005794//Golgi apparatus;GO:0030119//AP-type membrane coat adaptor complex;GO:0030131//clathrin adaptor complex,GO:0006886//intracellular protein transport;GO:0048490//anterograde synaptic vesicle transport;GO:0008089//anterograde axon cargo transport,-,K12398//Lysosome
10948,0,0,0,0,0,0,0,0,32,0,9,0,STARD3;StAR-related lipid transfer (START) domain containing 3,GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0031902//late endosome membrane,GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0006701//progesterone biosynthetic process;GO:0008202//steroid metabolic process;GO:0006629//lipid metabolic process;GO:0006839//mitochondrial transport,GO:0015485//cholesterol binding,-
10949,0,13,2,0,53,61,46,1,18,0,0,0,HNRNPA0;heterogeneous nuclear ribonucleoprotein A0,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex,"GO:0000398//mRNA splicing, via spliceosome;GO:0006954//inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0006397//mRNA processing",GO:0017091//AU-rich element binding;GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0019901//protein kinase binding,-
10950,0,0,0,5,0,0,0,0,11,0,0,0,"BTG3;BTG family, member 3",GO:0005737//cytoplasm,GO:0045930//negative regulation of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding,K14443//RNA degradation
10951,0,70,2,37,137,0,0,0,19,0,0,0,CBX1;chromobox homolog 1,"GO:0001939//female pronucleus;GO:0005721//pericentric heterochromatin;GO:0001940//male pronucleus;GO:0000785//chromatin;GO:0000775//chromosome, centromeric region;GO:0005720//nuclear heterochromatin;GO:0010369//chromocenter;GO:0005819//spindle;GO:0005654//nucleoplasm","GO:0045892//negative regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:1990226//histone methyltransferase binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
10952,0,1,0,49,54,10,1,0,20,0,0,0,SEC61B;Sec61 beta subunit,GO:0031205//endoplasmic reticulum Sec complex;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0000060//protein import into nucleus, translocation;GO:0030970//retrograde protein transport, ER to cytosol;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0048408//epidermal growth factor binding;GO:0043022//ribosome binding,K09481//Protein processing in endoplasmic reticulum;Phagosome;Protein export;Vibrio cholerae infection
10953,0,0,0,0,0,0,14,52,29,0,1,0,TOMM34;translocase of outer mitochondrial membrane 34,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005741//mitochondrial outer membrane;GO:0005730//nucleolus,GO:0006626//protein targeting to mitochondrion,GO:0031072//heat shock protein binding,K09553//Prion diseases
10954,0,0,0,0,0,19,33,2,21,0,2,0,"PDIA5;protein disulfide isomerase family A, member 5",GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,GO:0055114//oxidation-reduction process;GO:0034976//response to endoplasmic reticulum stress;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045454//cell redox homeostasis,GO:0003756//protein disulfide isomerase activity;GO:0016491//oxidoreductase activity,-
10955,0,0,0,2,0,0,54,51,11,0,0,0,SERINC3;serine incorporator 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0006665//sphingolipid metabolic process;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0015825//L-serine transport;GO:0006658//phosphatidylserine metabolic process,GO:0015194//L-serine transmembrane transporter activity,-
10956,0,0,0,0,12,9,0,0,28,0,10,0,"OS9;osteosarcoma amplified 9, endoplasmic reticulum lectin",GO:0005788//endoplasmic reticulum lumen;GO:0000836//Hrd1p ubiquitin ligase complex,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0006605//protein targeting;GO:0016567//protein ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0034976//response to endoplasmic reticulum stress;GO:0006621//protein retention in ER lumen,GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0001948//glycoprotein binding;GO:0002020//protease binding,K10088//Protein processing in endoplasmic reticulum
10957,0,50,4,34,84,35,0,0,30,0,0,0,PNRC1;proline-rich nuclear receptor coactivator 1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
10959,0,0,0,51,51,24,0,0,16,0,0,0,TMED2;transmembrane emp24 domain trafficking protein 2,GO:0030663//COPI-coated vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0030137//COPI-coated vesicle;GO:0032580//Golgi cisterna membrane;GO:0005789//endoplasmic reticulum membrane;GO:0042589//zymogen granule membrane;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0072661//protein targeting to plasma membrane;GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0035459//cargo loading into vesicle;GO:0006886//intracellular protein transport;GO:0034260//negative regulation of GTPase activity;GO:0048205//COPI coating of Golgi vesicle;GO:0007030//Golgi organization;GO:0001893//maternal placenta development;GO:0048598//embryonic morphogenesis,GO:0005515//protein binding,-
10960,0,9,1,0,2,9,17,0,20,0,0,0,"LMAN2;lectin, mannose-binding 2",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005615//extracellular space,"GO:0050766//positive regulation of phagocytosis;GO:0015031//protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER",GO:0001948//glycoprotein binding;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0005537//mannose binding;GO:0031072//heat shock protein binding,K10082//Protein processing in endoplasmic reticulum
10961,103,47,2,36,66,18,0,0,25,0,20,0,ERP29;endoplasmic reticulum protein 29,GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane;GO:0009986//cell surface;GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0009306//protein secretion;GO:0006886//intracellular protein transport;GO:0006457//protein folding,GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K09586//Protein processing in endoplasmic reticulum
10962,4,41,1,0,14,0,30,0,41,0,0,0,"MLLT11;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11",GO:0005622//intracellular,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0051901//positive regulation of mitochondrial depolarization;GO:0097193//intrinsic apoptotic signaling pathway",-,K11421//Lysine degradation
10963,194,127,1,57,113,25,23,709,41,35,201,1,STIP1;stress-induced phosphoprotein 1,GO:0005794//Golgi apparatus;GO:0005634//nucleus,GO:0006950//response to stress,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K09553//Prion diseases
10964,0,0,18,0,1,3,15,0,4,0,0,0,IFI44L;interferon-induced protein 44-like,GO:0005737//cytoplasm,GO:0006955//immune response;GO:0051607//defense response to virus,-,-
10965,0,19,1,36,8,0,0,82,39,0,169,1,ACOT2;acyl-CoA thioesterase 2,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0001676//long-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0000038//very long-chain fatty acid metabolic process,GO:0047617//acyl-CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0005102//receptor binding;GO:0052689//carboxylic ester hydrolase activity,K01068//Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites
10966,0,0,0,0,3,0,0,0,9,0,0,0,"RAB40B;RAB40B, member RAS oncogene family",GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0016567//protein ubiquitination;GO:0015031//protein transport,GO:0005525//GTP binding,-
10969,1,0,0,13,0,0,30,0,0,0,0,0,EBNA1BP2;EBNA1 binding protein 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane,GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding,-
10970,0,0,0,0,12,1,0,0,27,0,4,0,CKAP4;cytoskeleton-associated protein 4,GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005856//cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005811//lipid particle,-,GO:0044822//poly(A) RNA binding,K13999//Protein processing in endoplasmic reticulum
10971,0,147,2,209,581,0,2,1,0,0,0,0,"YWHAQ;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta",GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006605//protein targeting;GO:0097193//intrinsic apoptotic signaling pathway;GO:0061024//membrane organization;GO:0007264//small GTPase mediated signal transduction;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0021762//substantia nigra development",GO:0019904//protein domain specific binding;GO:0047485//protein N-terminus binding;GO:0005515//protein binding,K06630//Neurotrophin signaling pathway;Oocyte meiosis;Pathogenic Escherichia coli infection;Epstein-Barr virus infection;Cell cycle
10972,0,0,0,28,24,0,29,63,15,0,0,0,TMED10;transmembrane emp24-like trafficking protein 10 (yeast),GO:0042589//zymogen granule membrane;GO:0070062//extracellular vesicular exosome;GO:0030140//trans-Golgi network transport vesicle;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0030658//transport vesicle membrane;GO:0070765//gamma-secretase complex;GO:0030667//secretory granule membrane;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030137//COPI-coated vesicle;GO:0005789//endoplasmic reticulum membrane,"GO:0051259//protein oligomerization;GO:0043279//response to alkaloid;GO:0048208//COPII vesicle coating;GO:0001822//kidney development;GO:0035459//cargo loading into vesicle;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0001101//response to acid chemical;GO:0048205//COPI coating of Golgi vesicle;GO:0034205//beta-amyloid formation;GO:0045055//regulated secretory pathway;GO:0007030//Golgi organization",GO:0005515//protein binding;GO:0019905//syntaxin binding;GO:0032403//protein complex binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
10973,78,0,0,37,201,45,50,0,56,208,0,0,ASCC3;activating signal cointegrator 1 complex subunit 3,GO:0005794//Golgi apparatus;GO:0005622//intracellular;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0032508//DNA duplex unwinding;GO:0006307//DNA dealkylation involved in DNA repair;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated",GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0043140//ATP-dependent 3'-5' DNA helicase activity,K01529//Purine metabolism
10974,0,40,2,9,18,35,0,0,0,0,4,0,ADIRF;adipogenesis regulatory factor,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001023//regulation of response to drug;GO:0006351//transcription, DNA-templated;GO:0072719//cellular response to cisplatin;GO:0045600//positive regulation of fat cell differentiation;GO:0071478//cellular response to radiation",-,-
10975,0,22,1,9,2,7,0,0,0,0,0,0,"UQCR11;ubiquinol-cytochrome c reductase, complex III subunit XI",GO:0016021//integral component of membrane;GO:0070469//respiratory chain;GO:0005743//mitochondrial inner membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0006091//generation of precursor metabolites and energy;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,GO:0009055//electron carrier activity;GO:0008121//ubiquinol-cytochrome-c reductase activity,K00420//Cardiac muscle contraction;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease;Metabolic pathways
10978,0,0,0,0,0,11,0,0,0,0,0,0,CLP1;cleavage and polyadenylation factor I subunit 1,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005849//mRNA cleavage factor complex;GO:0005730//nucleolus;GO:0000214//tRNA-intron endonuclease complex,"GO:0021695//cerebellar cortex development;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0031124//mRNA 3'-end processing;GO:0008219//cell death;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0016310//phosphorylation;GO:0035087//siRNA loading onto RISC involved in RNA interference;GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome",GO:0005524//ATP binding;GO:0046404//ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0051736//ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity,K14399//mRNA surveillance pathway
10979,37,0,0,1,16,0,8,0,43,0,0,0,FERMT2;fermitin family member 2,GO:0031941//filamentous actin;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0031674//I band;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0005938//cell cortex,GO:0033622//integrin activation;GO:0034329//cell junction assembly;GO:0008360//regulation of cell shape;GO:0007160//cell-matrix adhesion;GO:0072657//protein localization to membrane;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0016055//Wnt signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0048041//focal adhesion assembly,"GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005515//protein binding",K06271//Focal adhesion;HTLV-I infection
10980,0,30,0,9,55,0,0,0,13,0,0,0,COPS6;COP9 signalosome subunit 6,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0008180//COP9 signalosome;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0010388//cullin deneddylation;GO:0016032//viral process,GO:0005515//protein binding,-
10981,0,0,0,0,0,0,0,0,45,0,0,0,"RAB32;RAB32, member RAS oncogene family",GO:0005739//mitochondrion;GO:0016020//membrane;GO:0042470//melanosome;GO:0005769//early endosome;GO:0030670//phagocytic vesicle membrane;GO:0045335//phagocytic vesicle;GO:0031905//early endosome lumen,GO:0019882//antigen processing and presentation;GO:0035646//endosome to melanosome transport;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0090382//phagosome maturation;GO:0015031//protein transport;GO:0032438//melanosome organization,GO:0032403//protein complex binding;GO:0035650//AP-1 adaptor complex binding;GO:0005525//GTP binding;GO:0035651//AP-3 adaptor complex binding;GO:0003924//GTPase activity;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding,-
10982,0,0,0,8,9,14,0,0,59,250,0,0,"MAPRE2;microtubule-associated protein, RP/EB family, member 2",GO:0035371//microtubule plus-end;GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm,GO:0008283//cell proliferation;GO:0007067//mitotic nuclear division;GO:0007165//signal transduction,GO:0008017//microtubule binding,-
10983,0,76,2,63,243,0,0,2,4,0,0,0,CCNI;cyclin I,-,GO:0007283//spermatogenesis;GO:0051726//regulation of cell cycle,-,K10146//p53 signaling pathway
10985,530,3,1,0,3,43,0,0,49,0,4,0,GCN1L1;GCN1 general control of amino-acid synthesis 1-like 1 (yeast),GO:0005840//ribosome;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006412//translation;GO:0006417//regulation of translation,"GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding",-
10987,0,47,0,0,44,41,11,4,2,0,0,0,COPS5;COP9 signalosome subunit 5,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus;GO:0008180//COP9 signalosome;GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0030054//cell junction,GO:0016579//protein deubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006508//proteolysis;GO:1990182//exosomal secretion;GO:0051726//regulation of cell cycle;GO:0046328//regulation of JNK cascade;GO:0006413//translational initiation;GO:0010388//cullin deneddylation;GO:0000338//protein deneddylation;GO:0006412//translation;GO:0006366//transcription from RNA polymerase II promoter,GO:0008237//metallopeptidase activity;GO:0004843//ubiquitin-specific protease activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003743//translation initiation factor activity,-
10988,0,1,0,13,115,31,0,0,7,0,0,0,METAP2;methionyl aminopeptidase 2,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane,"GO:0006508//proteolysis;GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0018206//peptidyl-methionine modification;GO:0016056//rhodopsin mediated signaling pathway;GO:0031365//N-terminal protein amino acid modification;GO:0016485//protein processing;GO:0070084//protein initiator methionine removal",GO:0004177//aminopeptidase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0008235//metalloexopeptidase activity;GO:0070006//metalloaminopeptidase activity,-
10989,0,22,1,26,71,0,0,0,17,0,0,0,"IMMT;inner membrane protein, mitochondrial",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0009409//response to cold;GO:0051560//mitochondrial calcium ion homeostasis,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K06267//ECM-receptor interaction
10990,0,0,0,0,0,0,0,0,8,0,0,0,"LILRB5;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5",GO:0016021//integral component of membrane,GO:0002376//immune system process;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response,GO:0004888//transmembrane signaling receptor activity,K06512//Osteoclast differentiation;B cell receptor signaling pathway
10991,0,0,0,0,0,0,27,0,19,0,0,0,"SLC38A3;solute carrier family 38, member 3",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006811//ion transport;GO:0015817//histidine transport;GO:0006867//asparagine transport;GO:0006868//glutamine transport;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0006865//amino acid transport;GO:0015808//L-alanine transport,GO:0015293//symporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0005290//L-histidine transmembrane transporter activity;GO:0015297//antiporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0015182//L-asparagine transmembrane transporter activity,K13576//Glutamatergic synapse;GABAergic synapse;Proximal tubule bicarbonate reclamation
10992,0,50,1,15,69,22,0,1,1,0,19,0,"SF3B2;splicing factor 3b, subunit 2, 145kDa",GO:0005730//nucleolus;GO:0005689//U12-type spliceosomal complex;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0016032//viral process;GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12829//Spliceosome
10993,0,0,0,0,0,26,0,0,16,50,10,284,SDS;serine dehydratase,GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0006094//gluconeogenesis;GO:0033590//response to cobalamin;GO:0043200//response to amino acid;GO:0042866//pyruvate biosynthetic process;GO:0006565//L-serine catabolic process,GO:0042803//protein homodimerization activity;GO:0003941//L-serine ammonia-lyase activity;GO:0004794//L-threonine ammonia-lyase activity;GO:0030170//pyridoxal phosphate binding,"K01752//Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Cysteine and methionine metabolism"
10994,0,0,0,0,9,36,0,0,18,165,3,0,ILVBL;ilvB (bacterial acetolactate synthase)-like,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008152//metabolic process,GO:0000287//magnesium ion binding;GO:0030976//thiamine pyrophosphate binding;GO:0016740//transferase activity,-
10998,128,26,20,6,47,13,0,214,13,43,29,0,"SLC27A5;solute carrier family 27 (fatty acid transporter), member 5",GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0009925//basal plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043234//protein complex,GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006642//triglyceride mobilization;GO:0046951//ketone body biosynthetic process;GO:0015721//bile acid and bile salt transport;GO:0015911//plasma membrane long-chain fatty acid transport;GO:0044281//small molecule metabolic process;GO:0000038//very long-chain fatty acid metabolic process,GO:0032403//protein complex binding;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0015245//fatty acid transporter activity;GO:0047747//cholate-CoA ligase activity,K08748//Bile secretion;PPAR signaling pathway;Primary bile acid biosynthesis;Metabolic pathways
10999,0,0,0,0,10,0,0,0,0,0,15,0,"SLC27A4;solute carrier family 27 (fatty acid transporter), member 4",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005902//microvillus;GO:0005789//endoplasmic reticulum membrane,GO:0042760//very long-chain fatty acid catabolic process;GO:0043588//skin development;GO:0007584//response to nutrient;GO:0006810//transport;GO:0015908//fatty acid transport;GO:0055085//transmembrane transport;GO:0001579//medium-chain fatty acid transport;GO:0044539//long-chain fatty acid import;GO:0015909//long-chain fatty acid transport;GO:0006629//lipid metabolic process;GO:0001676//long-chain fatty acid metabolic process,GO:0000166//nucleotide binding;GO:0015245//fatty acid transporter activity;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity,K08745//Fat digestion and absorption;PPAR signaling pathway
11000,0,0,0,0,11,0,0,41,18,0,0,0,"SLC27A3;solute carrier family 27 (fatty acid transporter), member 3",GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006631//fatty acid metabolic process,GO:0004321//fatty-acyl-CoA synthase activity;GO:0000166//nucleotide binding;GO:0016874//ligase activity,-
11001,0,0,0,0,0,0,0,0,0,0,1,530,"SLC27A2;solute carrier family 27 (fatty acid transporter), member 2",GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0044539//long-chain fatty acid import;GO:0097089//methyl-branched fatty acid metabolic process;GO:0001561//fatty acid alpha-oxidation;GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006635//fatty acid beta-oxidation;GO:0042760//very long-chain fatty acid catabolic process,GO:0070251//pristanate-CoA ligase activity;GO:0050197//phytanate-CoA ligase activity;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0015245//fatty acid transporter activity;GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005102//receptor binding,K08746//Peroxisome;PPAR signaling pathway
11005,0,1,0,0,0,0,36,51,58,0,0,0,"SPINK5;serine peptidase inhibitor, Kazal type 5",GO:0005938//cell cortex;GO:0097209//epidermal lamellar body;GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol,GO:0030855//epithelial cell differentiation;GO:0042640//anagen;GO:0009913//epidermal cell differentiation;GO:0030155//regulation of cell adhesion;GO:0010951//negative regulation of endopeptidase activity;GO:0050777//negative regulation of immune response;GO:0045580//regulation of T cell differentiation;GO:0035315//hair cell differentiation;GO:0016525//negative regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0045861//negative regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity,K06254//ECM-receptor interaction
11006,0,0,0,0,0,16,0,0,1,150,1,0,"LILRB4;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0045671//negative regulation of osteoclast differentiation;GO:0007165//signal transduction;GO:0002376//immune system process,GO:0005515//protein binding;GO:0003823//antigen binding;GO:0004872//receptor activity,K06512//B cell receptor signaling pathway;Osteoclast differentiation
11007,0,0,0,0,0,0,0,0,26,0,11,0,CCDC85B;coiled-coil domain containing 85B,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome,"GO:0030154//cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation;GO:0030308//negative regulation of cell growth",GO:0005515//protein binding,-
11009,0,0,0,0,0,2,10,0,17,0,0,0,IL24;interleukin 24,GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum,GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071353//cellular response to interleukin-4;GO:0008284//positive regulation of cell proliferation;GO:0071222//cellular response to lipopolysaccharide;GO:0042060//wound healing;GO:0033136//serine phosphorylation of STAT3 protein;GO:0006915//apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0030336//negative regulation of cell migration;GO:0043065//positive regulation of apoptotic process,GO:0005125//cytokine activity,K05444//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
1101,0,0,0,0,0,0,21,0,0,0,10,0,CHAD;chondroadherin,GO:0005578//proteinaceous extracellular matrix,GO:0060348//bone development;GO:1900155//negative regulation of bone trabecula formation;GO:0001502//cartilage condensation,-,K06248//Focal adhesion;ECM-receptor interaction
11010,0,39,292,347,318,17,36,0,0,0,187,1,GLIPR1;GLI pathogenesis-related 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process,-,-
11011,0,0,0,6,11,20,11,0,0,0,1,0,TLK2;tousled-like kinase 2,GO:0005730//nucleolus;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0006974//cellular response to DNA damage stimulus;GO:0018105//peptidyl-serine phosphorylation;GO:0007049//cell cycle;GO:0016568//chromatin modification;GO:0006468//protein phosphorylation;GO:0001672//regulation of chromatin assembly or disassembly;GO:0007059//chromosome segregation;GO:0071480//cellular response to gamma radiation;GO:0035556//intracellular signal transduction;GO:0010507//negative regulation of autophagy;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
11012,0,0,0,0,0,3,0,32,36,0,0,0,KLK11;kallikrein-related peptidase 11,GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005615//extracellular space,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
11013,0,0,0,0,15,0,0,0,0,0,0,0,TMSB15A;thymosin beta 15a,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0042989//sequestering of actin monomers;GO:0030036//actin cytoskeleton organization,GO:0003779//actin binding,K05764//Regulation of actin cytoskeleton
11014,89,41,1,19,61,0,15,0,6,0,0,0,KDELR2;KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005801//cis-Golgi network;GO:0005789//endoplasmic reticulum membrane,GO:0006621//protein retention in ER lumen;GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport,GO:0005046//KDEL sequence binding,K10949//Vibrio cholerae infection
11015,0,0,0,0,0,13,27,0,0,0,1,0,KDELR3;KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0016192//vesicle-mediated transport;GO:0006621//protein retention in ER lumen,GO:0046923//ER retention sequence binding,K10949//Vibrio cholerae infection
11016,0,55,0,61,108,14,15,0,64,0,15,0,ATF7;activating transcription factor 7,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0034399//nuclear periphery;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0016032//viral process;GO:0006355//regulation of transcription, DNA-templated",GO:0051019//mitogen-activated protein kinase binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
11017,0,23,0,0,56,0,0,0,9,0,0,0,SNRNP27;small nuclear ribonucleoprotein 27kDa (U4/U6.U5),GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0003676//nucleic acid binding;GO:0005515//protein binding,K12846//Spliceosome
11018,0,1,0,7,4,8,24,0,1,0,56,0,TMED1;transmembrane emp24 protein transport domain containing 1,GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0007267//cell-cell signaling;GO:0015031//protein transport;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0005102//receptor binding,-
11019,0,0,0,0,8,33,0,0,17,0,9,0,LIAS;lipoic acid synthetase,GO:0005739//mitochondrion,GO:0009249//protein lipoylation;GO:0006979//response to oxidative stress;GO:0001843//neural tube closure;GO:0009107//lipoate biosynthetic process;GO:0006954//inflammatory response;GO:0032496//response to lipopolysaccharide,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016992//lipoate synthase activity;GO:0046872//metal ion binding",K03644//Lipoic acid metabolism;Metabolic pathways
1102,0,1,0,2,73,0,15,0,93,0,0,0,RCBTB2;regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2,GO:0001669//acrosomal vesicle,GO:0032853//positive regulation of Ran GTPase activity,GO:0005087//Ran guanyl-nucleotide exchange factor activity,-
11020,0,0,0,0,1,0,0,0,1,0,0,0,IFT27;intraflagellar transport 27,GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B;GO:0005813//centrosome;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
11021,0,0,0,0,0,0,31,0,14,0,1,0,"RAB35;RAB35, member RAS oncogene family",GO:0045334//clathrin-coated endocytic vesicle;GO:0005739//mitochondrion;GO:0045171//intercellular bridge;GO:0031253//cell projection membrane;GO:0010008//endosome membrane;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005905//coated pit,GO:0000910//cytokinesis;GO:1990090//cellular response to nerve growth factor stimulus;GO:0007264//small GTPase mediated signal transduction;GO:0036010//protein localization to endosome;GO:0031175//neuron projection development;GO:0019882//antigen processing and presentation;GO:0006184//GTP catabolic process;GO:0048227//plasma membrane to endosome transport;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0008104//protein localization,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019003//GDP binding;GO:0005515//protein binding",-
11022,0,0,2,8,1,0,22,0,13,0,1,0,TDRKH;tudor and KH domain containing,GO:0005739//mitochondrion;GO:0071547//piP-body;GO:0071546//pi-body,GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0007140//male meiosis;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation,GO:0003723//RNA binding,K15979//Epstein-Barr virus infection
11023,0,0,0,0,0,12,0,0,62,0,12,0,VAX1;ventral anterior homeobox 1,GO:0005634//nucleus,"GO:0007420//brain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0060021//palate development;GO:0001764//neuron migration;GO:0006351//transcription, DNA-templated;GO:0043010//camera-type eye development;GO:0007406//negative regulation of neuroblast proliferation;GO:0035914//skeletal muscle cell differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding,-
11024,0,0,0,0,0,0,0,0,34,0,7,0,"LILRA1;leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response;GO:0006952//defense response;GO:0002376//immune system process,GO:0003823//antigen binding;GO:0004888//transmembrane signaling receptor activity,K06512//B cell receptor signaling pathway;Osteoclast differentiation
11025,0,20,0,0,0,17,0,120,15,0,5,1,"LILRB3;leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3",GO:0005887//integral component of plasma membrane,GO:0002376//immune system process;GO:0006952//defense response;GO:0007166//cell surface receptor signaling pathway;GO:0045671//negative regulation of osteoclast differentiation,GO:0004872//receptor activity;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity,K06512//Osteoclast differentiation;B cell receptor signaling pathway
11026,0,0,0,0,0,0,18,60,0,0,0,0,"LILRA3;leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3",GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0006952//defense response;GO:0007165//signal transduction;GO:0002376//immune system process,GO:0003823//antigen binding;GO:0004872//receptor activity,K06512//Osteoclast differentiation;B cell receptor signaling pathway
11027,104,0,0,0,0,0,34,2,2,0,0,0,"LILRA2;leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2",GO:0016021//integral component of membrane,GO:0006952//defense response;GO:0007165//signal transduction;GO:0002376//immune system process,GO:0003823//antigen binding;GO:0004872//receptor activity,K06512//B cell receptor signaling pathway;Osteoclast differentiation
1103,97,0,0,0,0,0,18,0,3,27,0,0,CHAT;choline O-acetyltransferase,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0030424//axon;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0042136//neurotransmitter biosynthetic process;GO:0016358//dendrite development;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0007274//neuromuscular synaptic transmission;GO:0006644//phospholipid metabolic process;GO:0007622//rhythmic behavior;GO:0007517//muscle organ development;GO:0007628//adult walking behavior;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0006656//phosphatidylcholine biosynthetic process;GO:0007529//establishment of synaptic specificity at neuromuscular junction;GO:0043179//rhythmic excitation,GO:0004102//choline O-acetyltransferase activity,K00623//Glycerophospholipid metabolism;Cholinergic synapse
11030,0,17,0,4,19,11,0,80,0,0,0,0,RBPMS;RNA binding protein with multiple splicing,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0060391//positive regulation of SMAD protein import into nucleus",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003713//transcription coactivator activity;GO:0008143//poly(A) binding,-
11031,0,0,0,5,96,33,36,0,58,0,2,0,"RAB31;RAB31, member RAS oncogene family",GO:0045335//phagocytic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0005769//early endosome,GO:0032869//cellular response to insulin stimulus;GO:0043001//Golgi to plasma membrane protein transport;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0090382//phagosome maturation;GO:0031623//receptor internalization;GO:0045055//regulated secretory pathway,GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07892//Endocytosis
11033,0,0,0,0,0,7,30,1,79,0,0,0,ADAP1;ArfGAP with dual PH domains 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0007166//cell surface receptor signaling pathway;GO:0043087//regulation of GTPase activity,"GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding",K12489//Endocytosis;K12486//Endocytosis;K12491//Endocytosis
11034,0,173,5,241,706,0,5,0,27,0,9,0,DSTN;destrin (actin depolymerizing factor),GO:0030864//cortical actin cytoskeleton;GO:0015629//actin cytoskeleton;GO:0070062//extracellular vesicular exosome,GO:0006928//cellular component movement;GO:0030836//positive regulation of actin filament depolymerization;GO:0051014//actin filament severing;GO:0030042//actin filament depolymerization;GO:0008154//actin polymerization or depolymerization,GO:0003779//actin binding,-
11035,0,0,0,0,0,0,26,0,11,0,11,0,RIPK3;receptor-interacting serine-threonine kinase 3,GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0097342//ripoptosome;GO:0005829//cytosol,"GO:0090312//positive regulation of protein deacetylation;GO:1990000//amyloid fibril formation;GO:0001914//regulation of T cell mediated cytotoxicity;GO:0070266//necroptotic process;GO:0048535//lymph node development;GO:0033077//T cell differentiation in thymus;GO:0097190//apoptotic signaling pathway;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032481//positive regulation of type I interferon production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0046006//regulation of activated T cell proliferation;GO:0048536//spleen development;GO:0043029//T cell homeostasis;GO:0051353//positive regulation of oxidoreductase activity;GO:0002819//regulation of adaptive immune response;GO:2000452//regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0032147//activation of protein kinase activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction;GO:0046777//protein autophosphorylation;GO:0010922//positive regulation of phosphatase activity;GO:0060545//positive regulation of necroptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0032649//regulation of interferon-gamma production;GO:0051260//protein homooligomerization;GO:0048538//thymus development;GO:0006464//cellular protein modification process;GO:0038061//NIK/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051351//positive regulation of ligase activity;GO:0070235//regulation of activation-induced cell death of T cells;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0002224//toll-like receptor signaling pathway",GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0004704//NF-kappaB-inducing kinase activity,K08847//Cytosolic DNA-sensing pathway
11036,0,0,0,0,0,0,0,0,4,0,0,0,"GTF2A1L;general transcription factor IIA, 1-like",GO:0005672//transcription factor TFIIA complex;GO:0005737//cytoplasm,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050890//cognition;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,K03122//Basal transcription factors
11037,0,2,1,24,91,0,0,0,16,0,0,0,STON1;stonin 1,GO:0030131//clathrin adaptor complex,GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0030100//regulation of endocytosis,-,K12393//Lysosome;K11447//Transcriptional misregulation in cancer
11039,0,0,0,3,0,0,2,0,27,0,0,0,"SMA4;glucuronidase, beta pseudogene",-,-,-,K01195//Porphyrin and chlorophyll metabolism;Glycosaminoglycan degradation;Metabolic pathways;Pentose and glucuronate interconversions;Starch and sucrose metabolism;Lysosome;Drug metabolism - other enzymes
1104,0,1,0,0,2,14,36,53,39,0,0,0,RCC1;regulator of chromosome condensation 1,GO:0000794//condensed nuclear chromosome;GO:0005730//nucleolus;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin,GO:0007067//mitotic nuclear division;GO:0007088//regulation of mitosis;GO:0016032//viral process;GO:0051225//spindle assembly;GO:0000082//G1/S transition of mitotic cell cycle;GO:0032853//positive regulation of Ran GTPase activity;GO:0007059//chromosome segregation;GO:0007052//mitotic spindle organization,GO:0003682//chromatin binding;GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0031492//nucleosomal DNA binding;GO:0005515//protein binding;GO:0042393//histone binding,-
11040,88,0,0,1,0,8,0,0,0,0,10,207,"PIM2;Pim-2 proto-oncogene, serine/threonine kinase",-,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0000082//G1/S transition of mitotic cell cycle;GO:0008637//apoptotic mitochondrial changes;GO:0007140//male meiosis;GO:0010508//positive regulation of autophagy;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008283//cell proliferation;GO:0009615//response to virus;GO:0050821//protein stabilization;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process",GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K08806//Acute myeloid leukemia
11041,0,0,0,0,10,0,0,56,39,0,0,0,"B3GNT1;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1",GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0030173//integral component of Golgi membrane,GO:0006486//protein glycosylation;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0030311//poly-N-acetyllactosamine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007411//axon guidance;GO:0030203//glycosaminoglycan metabolic process,"GO:0008532//N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity",K00741//Glycosphingolipid biosynthesis - lacto and neolacto series;Glycosaminoglycan biosynthesis - keratan sulfate;Metabolic pathways
11043,122,2,0,67,126,17,0,0,38,0,0,167,MID2;midline 2,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome,GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:1902187//negative regulation of viral release from host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035372//protein localization to microtubule,GO:0016874//ligase activity;GO:0008017//microtubule binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding;GO:0008270//zinc ion binding,-
11044,2,0,0,0,0,30,18,57,22,0,0,0,PAPD7;PAP associated domain containing 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006302//double-strand break repair;GO:0006261//DNA-dependent DNA replication;GO:0042493//response to drug;GO:0007076//mitotic chromosome condensation;GO:0007062//sister chromatid cohesion,GO:0003887//DNA-directed DNA polymerase activity;GO:0004652//polynucleotide adenylyltransferase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0043221//SMC family protein binding,K03514//RNA degradation
11045,0,0,0,0,0,8,0,0,9,0,0,1,UPK1A;uroplakin 1A,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0051259//protein oligomerization;GO:0030855//epithelial cell differentiation,GO:0042803//protein homodimerization activity;GO:0048029//monosaccharide binding,K06497//Lysosome
11046,0,0,0,0,32,13,0,0,35,0,0,0,"SLC35D2;solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0008643//carbohydrate transport;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:1901679//nucleotide transmembrane transport;GO:0006024//glycosaminoglycan biosynthetic process;GO:1901264//carbohydrate derivative transport;GO:0055085//transmembrane transport,GO:0005338//nucleotide-sugar transmembrane transporter activity,-
11047,0,0,0,7,30,13,55,0,6,0,1,0,ADRM1;adhesion regulating molecule 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0000502//proteasome complex;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0010950//positive regulation of endopeptidase activity;GO:0043248//proteasome assembly;GO:0006368//transcription elongation from RNA polymerase II promoter,GO:0070628//proteasome binding;GO:0061133//endopeptidase activator activity;GO:0002020//protease binding;GO:0005515//protein binding,-
1105,106,32,0,4,40,52,0,75,45,1,11,0,CHD1;chromodomain helicase DNA binding protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0032508//DNA duplex unwinding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification",GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0035064//methylated histone binding,-
11051,0,28,0,53,230,47,0,0,8,0,0,0,NUDT21;nudix (nucleoside diphosphate linked moiety X)-type motif 21,GO:0042382//paraspeckles;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0005849//mRNA cleavage factor complex,"GO:0006366//transcription from RNA polymerase II promoter;GO:0051262//protein tetramerization;GO:0000398//mRNA splicing, via spliceosome;GO:0006378//mRNA polyadenylation;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0031124//mRNA 3'-end processing",GO:0017091//AU-rich element binding;GO:0016787//hydrolase activity;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0042826//histone deacetylase binding;GO:0003729//mRNA binding,K14397//mRNA surveillance pathway
11054,0,1,0,0,0,0,0,0,105,0,0,0,OGFR;opioid growth factor receptor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,GO:0001558//regulation of cell growth;GO:0038003//opioid receptor signaling pathway,GO:0004985//opioid receptor activity,-
11055,0,0,0,0,0,1,20,0,21,0,0,0,ZPBP;zona pellucida binding protein,GO:0005576//extracellular region;GO:0002199//zona pellucida receptor complex;GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0044297//cell body,GO:0001675//acrosome assembly;GO:0007339//binding of sperm to zona pellucida,-,-
11056,0,0,41,21,1,24,0,0,39,0,6,0,DDX52;DEAD (Asp-Glu-Ala-Asp) box polypeptide 52,GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0044822//poly(A) RNA binding,-
11057,0,0,1,25,37,80,74,124,27,3,22,1,ABHD2;abhydrolase domain containing 2,GO:0016021//integral component of membrane,GO:0030336//negative regulation of cell migration;GO:0009611//response to wounding;GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
11059,0,28,1,61,121,38,0,0,35,0,0,0,WWP1;WW domain containing E3 ubiquitin protein ligase 1,GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0055085//transmembrane transport;GO:0016567//protein ubiquitination;GO:0007417//central nervous system development;GO:0034220//ion transmembrane transport;GO:0046718//viral entry into host cell;GO:0045892//negative regulation of transcription, DNA-templated",GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K05633//Endocytosis;Ubiquitin mediated proteolysis
1106,97,146,1,90,299,18,33,0,100,1,0,0,CHD2;chromodomain helicase DNA binding protein 2,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0032508//DNA duplex unwinding;GO:0016568//chromatin modification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0060218//hematopoietic stem cell differentiation",GO:0044822//poly(A) RNA binding;GO:0042393//histone binding;GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding,-
11060,0,58,12,6,5,9,25,20,25,104,9,0,WWP2;WW domain containing E3 ubiquitin protein ligase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination;GO:0051224//negative regulation of protein transport;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0010629//negative regulation of gene expression;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042391//regulation of membrane potential;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0034765//regulation of ion transmembrane transport;GO:0070534//protein K63-linked ubiquitination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046718//viral entry into host cell;GO:0032410//negative regulation of transporter activity",GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0001085//RNA polymerase II transcription factor binding,K05630//Ubiquitin mediated proteolysis
11061,0,0,0,0,0,0,44,0,13,0,0,0,LECT1;leukocyte cell derived chemotaxin 1,GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005578//proteinaceous extracellular matrix,GO:0001501//skeletal system development;GO:0016525//negative regulation of angiogenesis;GO:0006029//proteoglycan metabolic process;GO:0051216//cartilage development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001886//endothelial cell morphogenesis,-,K01099//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
11062,0,35,0,0,18,0,14,69,11,0,7,0,DUS4L;dihydrouridine synthase 4-like (S. cerevisiae),-,GO:0002943//tRNA dihydrouridine synthesis;GO:0055114//oxidation-reduction process,GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding,-
11063,0,60,0,27,56,61,0,207,60,0,21,0,SOX30;SRY (sex determining region Y)-box 30,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0031960//response to corticosteroid;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis",GO:0043565//sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
11064,0,29,1,9,30,17,33,0,44,0,17,0,CNTRL;centriolin,GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0051301//cell division;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
11065,0,0,0,0,0,0,0,0,8,0,3,0,UBE2C;ubiquitin-conjugating enzyme E2C,GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol,GO:0051488//activation of anaphase-promoting complex activity;GO:0010994//free ubiquitin chain polymerization;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0008054//cyclin catabolic process;GO:0007094//mitotic spindle assembly checkpoint;GO:0010458//exit from mitosis;GO:0031536//positive regulation of exit from mitosis;GO:0000278//mitotic cell cycle;GO:0070936//protein K48-linked ubiquitination;GO:0016567//protein ubiquitination,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K06688//Ubiquitin mediated proteolysis
11066,0,0,0,0,25,0,0,0,0,0,0,0,SNRNP35;small nuclear ribonucleoprotein 35kDa (U11/U12),GO:0005634//nucleus;GO:0005689//U12-type spliceosomal complex,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0003723//RNA binding;GO:0000166//nucleotide binding,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
11067,0,0,0,0,0,0,15,34,13,0,0,0,C10orf10;chromosome 10 open reading frame 10,GO:0005739//mitochondrion,-,-,-
11068,0,68,75,15,61,0,0,0,65,0,49,0,"CYB561D2;cytochrome b561 family, member D2",GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding,K04859//MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy
11069,0,0,0,7,0,3,0,0,93,211,16,0,RAPGEF4;Rap guanine nucleotide exchange factor (GEF) 4,GO:0005952//cAMP-dependent protein kinase complex;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane,GO:0017156//calcium ion-dependent exocytosis;GO:0017157//regulation of exocytosis;GO:0007596//blood coagulation;GO:0050796//regulation of insulin secretion;GO:0032320//positive regulation of Ras GTPase activity;GO:0006112//energy reserve metabolic process;GO:0019933//cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0030073//insulin secretion;GO:0045859//regulation of protein kinase activity;GO:0030168//platelet activation;GO:0043547//positive regulation of GTPase activity;GO:0044281//small molecule metabolic process,GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0030552//cAMP binding;GO:0005515//protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0005085//guanyl-nucleotide exchange factor activity,K04351//Leukocyte transendothelial migration
1107,98,218,9,103,456,25,33,2,43,131,9,306,CHD3;chromodomain helicase DNA binding protein 3,GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0005813//centrosome;GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006333//chromatin assembly or disassembly;GO:0032508//DNA duplex unwinding;GO:0007051//spindle organization;GO:0051297//centrosome organization;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
11070,0,0,0,2,13,0,17,0,0,0,24,0,TMEM115;transmembrane protein 115,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005634//nucleus,GO:0008285//negative regulation of cell proliferation,-,-
11072,0,12,0,0,4,0,0,0,19,0,0,0,DUSP14;dual specificity phosphatase 14,-,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0000188//inactivation of MAPK activity,GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0044822//poly(A) RNA binding;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
11073,0,2,0,9,69,0,0,0,104,139,0,311,TOPBP1;topoisomerase (DNA) II binding protein 1,GO:0000794//condensed nuclear chromosome;GO:0016605//PML body;GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus,GO:0006974//cellular response to DNA damage stimulus;GO:0006259//DNA metabolic process;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0008022//protein C-terminus binding,-
11075,0,0,0,0,0,47,0,0,2,0,0,0,STMN2;stathmin 2,GO:0030424//axon;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0043005//neuron projection;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0031982//vesicle;GO:0005737//cytoplasm,GO:1990090//cellular response to nerve growth factor stimulus;GO:0031115//negative regulation of microtubule polymerization;GO:0010977//negative regulation of neuron projection development;GO:0010976//positive regulation of neuron projection development;GO:0031117//positive regulation of microtubule depolymerization;GO:0007026//negative regulation of microtubule depolymerization,GO:0048306//calcium-dependent protein binding;GO:0005515//protein binding,K04381//MAPK signaling pathway
11076,0,0,53,4,26,18,0,113,34,0,38,1,TPPP;tubulin polymerization promoting protein,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0046785//microtubule polymerization;GO:0032273//positive regulation of protein polymerization;GO:0031334//positive regulation of protein complex assembly;GO:0001578//microtubule bundle formation,GO:0015631//tubulin binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
11077,0,0,0,0,0,0,0,0,35,0,0,49,HSF2BP;heat shock transcription factor 2 binding protein,GO:0005829//cytosol,GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter,-,-
11078,0,25,0,0,11,24,78,3,120,84,1,0,TRIOBP;TRIO and F-actin binding protein,GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0005925//focal adhesion;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007067//mitotic nuclear division;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0051016//barbed-end actin filament capping;GO:0030047//actin modification,GO:0045159//myosin II binding;GO:0031625//ubiquitin protein ligase binding;GO:0017049//GTP-Rho binding;GO:0051015//actin filament binding,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
11079,1,482,296,488,1172,0,62,438,174,2,1254,332,RER1;retention in endoplasmic reticulum sorting receptor 1,GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0030173//integral component of Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0071340//skeletal muscle acetylcholine-gated channel clustering",GO:0033130//acetylcholine receptor binding,-
1108,77,45,0,37,153,5,2,90,12,0,13,0,CHD4;chromodomain helicase DNA binding protein 4,GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0016581//NuRD complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016020//membrane,"GO:0032508//DNA duplex unwinding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0043044//ATP-dependent chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0051225//spindle assembly",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0031492//nucleosomal DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
11081,93,0,0,0,0,0,40,0,11,0,0,0,KERA;keratocan,GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen,GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0061303//cornea development in camera-type eye;GO:0042340//keratan sulfate catabolic process,-,-
11082,0,0,0,0,0,0,22,0,0,0,0,0,ESM1;endothelial cell-specific molecule 1,GO:0005576//extracellular region,GO:0002040//sprouting angiogenesis;GO:0001558//regulation of cell growth;GO:0008284//positive regulation of cell proliferation;GO:1902204//positive regulation of hepatocyte growth factor receptor signaling pathway;GO:0001525//angiogenesis,GO:0005178//integrin binding;GO:0005171//hepatocyte growth factor receptor binding;GO:0005520//insulin-like growth factor binding,-
11083,0,37,19,31,15,52,26,26,95,239,1,270,DIDO1;death inducer-obliterator 1,GO:0005819//spindle;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0097190//apoptotic signaling pathway;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,K13911//Salivary secretion
11085,0,0,0,0,0,9,27,0,1,0,0,0,ADAM30;ADAM metallopeptidase domain 30,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0032504//multicellular organism reproduction;GO:0007339//binding of sperm to zona pellucida;GO:0007338//single fertilization;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity,-
11086,0,0,0,0,0,0,0,0,7,5,0,0,ADAM29;ADAM metallopeptidase domain 29,GO:0005887//integral component of plasma membrane,GO:0007283//spermatogenesis;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity,-
1109,0,0,0,0,0,0,19,0,27,0,0,0,"AKR1C4;aldo-keto reductase family 1, member C4",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,"GO:0008209//androgen metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0044597//daunorubicin metabolic process;GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process;GO:0007603//phototransduction, visible light;GO:0044598//doxorubicin metabolic process;GO:0015721//bile acid and bile salt transport;GO:0044281//small molecule metabolic process;GO:0071395//cellular response to jasmonic acid stimulus;GO:0001523//retinoid metabolic process","GO:0009055//electron carrier activity;GO:0047743//chlordecone reductase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0047023//androsterone dehydrogenase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0015125//bile acid transmembrane transporter activity;GO:0001758//retinal dehydrogenase activity","K05295//Steroid hormone biosynthesis;K00212//Primary bile acid biosynthesis;Metabolic pathways;Arachidonic acid metabolism;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00092//Metabolic pathways;Primary bile acid biosynthesis;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00100//Metabolic pathways;Linoleic acid metabolism;Two-component system;Fructose and mannose metabolism;Naphthalene degradation;Limonene and pinene degradation;Chloroalkane and chloroalkene degradation;Butanoate metabolism;Microbial metabolism in diverse environments;Bisphenol degradation;Benzoate degradation;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Methane metabolism;K00089//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Metabolic pathways;Primary bile acid biosynthesis;Arachidonic acid metabolism;K00037//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Metabolic pathways;Primary bile acid biosynthesis"
11091,0,25,1,0,45,0,0,0,10,165,14,0,WDR5;WD repeat domain 5,GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0035097//histone methyltransferase complex;GO:0071339//MLL1 complex;GO:0048188//Set1C/COMPASS complex;GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex,"GO:0006351//transcription, DNA-templated;GO:0001501//skeletal system development;GO:0051568//histone H3-K4 methylation;GO:0043981//histone H4-K5 acetylation;GO:0006325//chromatin organization;GO:0045722//positive regulation of gluconeogenesis;GO:0043982//histone H4-K8 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated",GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0005515//protein binding,-
11092,20,0,0,0,0,0,0,0,23,0,0,0,C9orf9;chromosome 9 open reading frame 9,GO:0005881//cytoplasmic microtubule,-,-,-
11093,1,9,0,6,7,11,16,0,28,59,17,61,"ADAMTS13;ADAM metallopeptidase with thrombospondin type 1 motif, 13",GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0007160//cell-matrix adhesion;GO:0009100//glycoprotein metabolic process;GO:0034612//response to tumor necrosis factor;GO:0006508//proteolysis;GO:0034341//response to interferon-gamma;GO:0043171//peptide catabolic process;GO:0016485//protein processing;GO:0070670//response to interleukin-4;GO:0007229//integrin-mediated signaling pathway;GO:0030168//platelet activation,GO:0008237//metallopeptidase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0004222//metalloendopeptidase activity,-
11094,0,0,0,0,0,0,0,65,82,0,0,0,CACFD1;calcium channel flower domain containing 1,GO:0030285//integral component of synaptic vesicle membrane,GO:0070588//calcium ion transmembrane transport;GO:0048488//synaptic vesicle endocytosis,GO:0005262//calcium channel activity,-
11095,49,0,0,9,2,1,0,76,18,0,66,0,"ADAMTS8;ADAM metallopeptidase with thrombospondin type 1 motif, 8",GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,GO:0035435//phosphate ion transmembrane transport;GO:0008285//negative regulation of cell proliferation;GO:0006508//proteolysis,GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0009673//low-affinity phosphate transmembrane transporter activity;GO:0004222//metalloendopeptidase activity,-
11096,0,0,0,0,0,15,27,32,63,0,0,0,"ADAMTS5;ADAM metallopeptidase with thrombospondin type 1 motif, 5",GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0006508//proteolysis;GO:0042742//defense response to bacterium,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding,-
11097,0,0,0,0,13,13,6,0,0,0,0,0,NUPL2;nucleoporin like 2,GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0019221//cytokine-mediated signaling pathway;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0006611//protein export from nucleus;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005049//nuclear export signal receptor activity,K14321//RNA transport
11098,125,35,19,78,147,0,0,0,55,0,187,1,"PRSS23;protease, serine, 23",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K02354//Pathways in cancer;HTLV-I infection;Wnt signaling pathway;Basal cell carcinoma;Melanogenesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption
11099,0,0,1,0,15,0,0,0,37,126,11,0,"PTPN21;protein tyrosine phosphatase, non-receptor type 21",GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding,-
111,0,0,0,0,0,0,35,27,60,12,1,0,ADCY5;adenylate cyclase 5,GO:0072372//primary cilium;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006112//energy reserve metabolic process;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0006833//water transport;GO:0034199//activation of protein kinase A activity;GO:0001973//adenosine receptor signaling pathway;GO:0055085//transmembrane transport;GO:0035556//intracellular signal transduction;GO:0007202//activation of phospholipase C activity;GO:0050885//neuromuscular process controlling balance;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007626//locomotory behavior;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0006171//cAMP biosynthetic process;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0046982//protein heterodimerization activity;GO:0005524//ATP binding;GO:0008179//adenylate cyclase binding,K08045//Alcoholism;Serotonergic synapse;Pancreatic secretion;Progesterone-mediated oocyte maturation;Chemokine signaling pathway;GnRH signaling pathway;Dopaminergic synapse;Cocaine addiction;Gap junction;Purine metabolism;Amphetamine addiction;Glutamatergic synapse;Vascular smooth muscle contraction;Oocyte meiosis;Morphine addiction;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Salivary secretion;GABAergic synapse;Cholinergic synapse;HTLV-I infection;Gastric acid secretion;Melanogenesis;Bile secretion
11100,89,31,2,22,103,46,14,0,13,0,6,2,HNRNPUL1;heterogeneous nuclear ribonucleoprotein U-like 1,GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0009615//response to virus;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0003723//RNA binding,K15047//Influenza A
11101,9,1,0,30,156,67,0,2,52,0,25,0,ATE1;arginyltransferase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0016598//protein arginylation,GO:0005515//protein binding;GO:0004057//arginyltransferase activity,-
11102,0,0,0,6,4,4,0,0,0,0,0,0,RPP14;ribonuclease P/MRP 14kDa subunit,GO:0005634//nucleus,"GO:0008033//tRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0004526//ribonuclease P activity;GO:0003723//RNA binding,K14529//RNA transport
11103,0,0,40,39,205,65,81,0,80,0,16,0,"KRR1;KRR1, small subunit (SSU) processome component, homolog (yeast)",GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
11104,0,0,0,7,20,0,4,0,11,0,6,0,KATNA1;katanin p60 (ATPase containing) subunit A 1,GO:0005886//plasma membrane;GO:0005811//lipid particle;GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0030496//midbody;GO:0030424//axon;GO:0005634//nucleus;GO:0000922//spindle pole;GO:0005874//microtubule,GO:0010977//negative regulation of neuron projection development;GO:0007067//mitotic nuclear division;GO:0051013//microtubule severing;GO:0006200//ATP catabolic process;GO:0031122//cytoplasmic microtubule organization;GO:0008104//protein localization;GO:0001764//neuron migration;GO:0001578//microtubule bundle formation,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0045502//dynein binding;GO:0008017//microtubule binding;GO:0046982//protein heterodimerization activity;GO:0008568//microtubule-severing ATPase activity,-
11105,0,0,0,0,0,0,28,0,26,0,0,0,PRDM7;PR domain containing 7,GO:0005634//nucleus;GO:0005694//chromosome,"GO:0034968//histone lysine methylation;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity,-
11108,0,26,1,1,62,10,0,0,65,183,0,0,PRDM4;PR domain containing 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0032259//methylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045786//negative regulation of cell cycle",GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,K12463//Neurotrophin signaling pathway
1111,10,0,52,49,92,22,19,236,53,0,186,69,CHEK1;checkpoint kinase 1,"GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0000794//condensed nuclear chromosome;GO:0005730//nucleolus;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0005813//centrosome",GO:0042127//regulation of cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0046602//regulation of mitotic centrosome separation;GO:0006281//DNA repair;GO:0035407//histone H3-T11 phosphorylation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006975//DNA damage induced protein phosphorylation;GO:0090399//replicative senescence;GO:0018107//peptidyl-threonine phosphorylation;GO:0006260//DNA replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0071260//cellular response to mechanical stimulus;GO:0000077//DNA damage checkpoint;GO:0031572//G2 DNA damage checkpoint;GO:0010767//regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0071313//cellular response to caffeine;GO:0045839//negative regulation of mitosis;GO:2000615//regulation of histone H3-K9 acetylation;GO:0048096//chromatin-mediated maintenance of transcription,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0035402//histone kinase activity (H3-T11 specific);GO:0005524//ATP binding,K02216//Meiosis - yeast;HTLV-I infection;Cell cycle - yeast;Cell cycle;p53 signaling pathway
11112,0,26,1,33,85,8,0,0,0,0,6,0,HIBADH;3-hydroxyisobutyrate dehydrogenase,GO:0005759//mitochondrial matrix,GO:0009083//branched-chain amino acid catabolic process;GO:0006574//valine catabolic process;GO:0006098//pentose-phosphate shunt;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process,GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity;GO:0051287//NAD binding;GO:0008442//3-hydroxyisobutyrate dehydrogenase activity,"K00020//Glutathione metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;Pentose phosphate pathway"
11113,0,0,0,0,6,37,49,49,105,137,33,600,CIT;citron rho-interacting serine/threonine kinase,GO:0031985//Golgi cisterna;GO:0043025//neuronal cell body;GO:0005773//vacuole;GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0001726//ruffle;GO:0005886//plasma membrane,GO:0000910//cytokinesis;GO:0008064//regulation of actin polymerization or depolymerization;GO:0007067//mitotic nuclear division;GO:0050774//negative regulation of dendrite morphogenesis;GO:0050790//regulation of catalytic activity;GO:0048699//generation of neurons;GO:0016358//dendrite development;GO:0000070//mitotic sister chromatid segregation;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0035556//intracellular signal transduction;GO:0007283//spermatogenesis;GO:0007030//Golgi organization;GO:0006468//protein phosphorylation,GO:0030165//PDZ domain binding;GO:0005524//ATP binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0017124//SH3 domain binding;GO:0046872//metal ion binding;GO:0017048//Rho GTPase binding,-
11116,0,0,0,12,32,0,0,0,0,0,0,0,FGFR1OP;FGFR1 oncogene partner,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005829//cytosol,GO:0008284//positive regulation of cell proliferation;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0006469//negative regulation of protein kinase activity;GO:0034453//microtubule anchoring;GO:0030307//positive regulation of cell growth;GO:0030335//positive regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0030292//protein tyrosine kinase inhibitor activity;GO:0004713//protein tyrosine kinase activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K11447//Transcriptional misregulation in cancer
11117,0,28,0,0,25,19,0,112,10,1,0,0,EMILIN1;elastin microfibril interfacer 1,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix,GO:0010811//positive regulation of cell-substrate adhesion;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization,GO:0030023//extracellular matrix constituent conferring elasticity;GO:0042802//identical protein binding;GO:0005515//protein binding,-
11118,0,0,0,0,7,11,0,0,0,0,0,0,"BTN3A2;butyrophilin, subfamily 3, member A2",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0072643//interferon-gamma secretion;GO:0002456//T cell mediated immunity,-,-
11119,0,0,0,0,0,21,0,51,51,0,0,0,"BTN3A1;butyrophilin, subfamily 3, member A1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0072643//interferon-gamma secretion;GO:0050663//cytokine secretion;GO:0050852//T cell receptor signaling pathway;GO:0050798//activated T cell proliferation,GO:0005515//protein binding,-
1112,1,76,1,52,264,0,0,41,32,1,0,269,FOXN3;forkhead box N3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007095//mitotic G2 DNA damage checkpoint",GO:0008022//protein C-terminus binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
11120,0,1,0,0,15,0,5,0,4,0,0,0,"BTN2A1;butyrophilin, subfamily 2, member A1",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006629//lipid metabolic process,-,-
11122,279,0,0,0,0,37,0,0,111,0,6,0,"PTPRT;protein tyrosine phosphatase, receptor type, T",GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155//cell adhesion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0045296//cadherin binding;GO:0045295//gamma-catenin binding;GO:0070097//delta-catenin binding;GO:0045294//alpha-catenin binding;GO:0008013//beta-catenin binding,-
11123,0,62,5,198,788,18,0,1,19,0,80,0,RCAN3;RCAN family member 3,-,GO:0009653//anatomical structure morphogenesis;GO:0019722//calcium-mediated signaling,GO:0003723//RNA binding;GO:0031013//troponin I binding,-
11124,0,46,1,14,103,35,0,0,33,0,0,0,FAF1;Fas (TNFRSF6) associated factor 1,GO:0005829//cytosol;GO:0034098//Cdc48p-Npl4p-Ufd1p AAA ATPase complex;GO:0031265//CD95 death-inducing signaling complex;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope,GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0008219//cell death;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031334//positive regulation of protein complex assembly;GO:0045859//regulation of protein kinase activity;GO:0042176//regulation of protein catabolic process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0006915//apoptotic process;GO:0030155//regulation of cell adhesion;GO:0043065//positive regulation of apoptotic process,GO:0043130//ubiquitin binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0019904//protein domain specific binding;GO:0051059//NF-kappaB binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0019887//protein kinase regulator activity,K04649//Ubiquitin mediated proteolysis
11126,49,0,0,0,0,0,0,0,0,0,0,0,CD160;CD160 molecule,GO:0005886//plasma membrane;GO:0046658//anchored component of plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response;GO:0006968//cellular defense response;GO:0008283//cell proliferation;GO:0050829//defense response to Gram-negative bacterium,GO:0032393//MHC class I receptor activity;GO:0004872//receptor activity;GO:0005102//receptor binding,-
11128,72,0,0,19,34,70,34,0,31,0,0,0,"POLR3A;polymerase (RNA) III (DNA directed) polypeptide A, 155kDa",GO:0016020//membrane;GO:0005829//cytosol;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0006386//termination of RNA polymerase III transcription;GO:0032728//positive regulation of interferon-beta production",GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0003682//chromatin binding;GO:0032549//ribonucleoside binding,K03018//Metabolic pathways;Cytosolic DNA-sensing pathway;RNA polymerase;Epstein-Barr virus infection;Purine metabolism;Pyrimidine metabolism
11129,0,1,0,0,0,29,0,0,53,0,11,0,CLASRP;CLK4-associating serine/arginine rich protein,GO:0005634//nucleus,GO:0006397//mRNA processing;GO:0008380//RNA splicing,-,-
1113,0,0,0,0,0,0,0,0,28,0,0,0,CHGA;chromogranin A (parathyroid secretory protein 1),GO:0030141//secretory granule;GO:0005576//extracellular region;GO:0030658//transport vesicle membrane;GO:0048471//perinuclear region of cytoplasm,GO:0008217//regulation of blood pressure,-,-
11130,106,0,0,0,0,18,0,0,1,0,0,0,ZWINT;ZW10 interacting kinetochore protein,GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007093//mitotic cell cycle checkpoint;GO:0000070//mitotic sister chromatid segregation;GO:0051649//establishment of localization in cell;GO:0000278//mitotic cell cycle,GO:0005515//protein binding;GO:0047485//protein N-terminus binding,-
11131,0,0,0,0,0,0,0,0,18,0,0,0,CAPN11;calpain 11,GO:0005737//cytoplasm;GO:0001669//acrosomal vesicle,GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
11132,0,0,0,22,0,1,0,0,26,0,12,0,CAPN10;calpain 10,GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005623//cell,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0032388//positive regulation of intracellular transport;GO:0032024//positive regulation of insulin secretion;GO:0006508//proteolysis;GO:0097050//type B pancreatic cell apoptotic process;GO:0031532//actin cytoskeleton reorganization;GO:0032869//cellular response to insulin stimulus;GO:2000676//positive regulation of type B pancreatic cell apoptotic process;GO:0046326//positive regulation of glucose import,GO:0008092//cytoskeletal protein binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0000149//SNARE binding,-
11133,0,0,0,0,0,0,0,0,0,0,0,182,KPTN;kaptin (actin binding protein),GO:0015629//actin cytoskeleton;GO:0005815//microtubule organizing center;GO:0032420//stereocilium;GO:0030426//growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0007605//sensory perception of sound;GO:0007015//actin filament organization;GO:0006928//cellular component movement,GO:0003779//actin binding,-
11135,0,0,0,0,0,0,0,0,26,107,0,0,CDC42EP1;CDC42 effector protein (Rho GTPase binding) 1,GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton,GO:0007266//Rho protein signal transduction;GO:0031274//positive regulation of pseudopodium assembly;GO:0008360//regulation of cell shape,GO:0005515//protein binding,-
11136,70,0,0,0,0,0,0,0,0,0,0,0,"SLC7A9;solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9",GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane,GO:0050900//leukocyte migration;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0006461//protein complex assembly;GO:0055085//transmembrane transport;GO:0015811//L-cystine transport;GO:0006520//cellular amino acid metabolic process;GO:0007596//blood coagulation;GO:0015804//neutral amino acid transport;GO:0006810//transport;GO:0006811//ion transport,GO:0015184//L-cystine transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0042605//peptide antigen binding;GO:0005515//protein binding;GO:0015171//amino acid transmembrane transporter activity,K13868//Protein digestion and absorption
11137,0,0,0,50,37,13,0,47,61,0,0,1,PWP1;PWP1 homolog (S. cerevisiae),GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated",-,-
11138,0,36,9,65,92,25,29,74,17,52,60,0,"TBC1D8;TBC1 domain family, member 8 (with GRAM domain)",GO:0016020//membrane,GO:0008015//blood circulation;GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly;GO:0008284//positive regulation of cell proliferation,GO:0005509//calcium ion binding;GO:0005097//Rab GTPase activator activity,K15014//Alcoholism
1114,0,0,0,0,0,0,0,0,6,0,0,0,CHGB;chromogranin B (secretogranin 1),GO:0005576//extracellular region;GO:0030141//secretory granule,-,GO:0005179//hormone activity;GO:0005515//protein binding,-
11140,0,38,0,8,10,0,0,0,80,0,0,0,CDC37;cell division cycle 37,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0070062//extracellular vesicular exosome,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0006605//protein targeting;GO:0060338//regulation of type I interferon-mediated signaling pathway,GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0051087//chaperone binding;GO:0051879//Hsp90 protein binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0043422//protein kinase B binding;GO:0051082//unfolded protein binding,-
11141,0,0,0,0,0,0,22,0,75,0,0,0,IL1RAPL1;interleukin 1 receptor accessory protein-like 1,GO:0005737//cytoplasm;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030424//axon,GO:0010975//regulation of neuron projection development;GO:0007165//signal transduction;GO:0045920//negative regulation of exocytosis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0070588//calcium ion transmembrane transport;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0030182//neuron differentiation;GO:0097105//presynaptic membrane assembly,GO:0005102//receptor binding;GO:0019966//interleukin-1 binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding,-
11142,66,0,0,0,3,33,16,0,33,0,0,0,"PKIG;protein kinase (cAMP-dependent, catalytic) inhibitor gamma",-,GO:0007165//signal transduction;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042308//negative regulation of protein import into nucleus,GO:0004862//cAMP-dependent protein kinase inhibitor activity,K15985//Alcoholism
11143,0,1,0,15,117,0,47,0,23,0,1,0,KAT7;K(lysine) acetyltransferase 7,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0000123//histone acetyltransferase complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0043983//histone H4-K12 acetylation;GO:0043966//histone H3 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0006260//DNA replication;GO:0006325//chromatin organization;GO:0043981//histone H4-K5 acetylation;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0004402//histone acetyltransferase activity,-
11144,0,0,0,0,0,8,0,13,7,0,0,0,DMC1;DNA meiotic recombinase 1,"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0000794//condensed nuclear chromosome;GO:0005694//chromosome",GO:0007126//meiotic nuclear division;GO:0001556//oocyte maturation;GO:0001541//ovarian follicle development;GO:0007129//synapsis;GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0007286//spermatid development;GO:0007292//female gamete generation;GO:0006200//ATP catabolic process;GO:0007141//male meiosis I,GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0005515//protein binding;GO:0003677//DNA binding,K10872//Meiosis - yeast
11145,0,0,0,0,0,0,0,1,9,0,0,0,"PLA2G16;phospholipase A2, group XVI",GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm,GO:0016042//lipid catabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0045786//negative regulation of cell cycle;GO:0006644//phospholipid metabolic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process,GO:0004623//phospholipase A2 activity;GO:0052740//1-acyl-2-lysophosphatidylserine acylhydrolase activity;GO:0008970//phosphatidylcholine 1-acylhydrolase activity;GO:0052739//phosphatidylserine 1-acylhydrolase activity;GO:0005515//protein binding,K00678//Retinol metabolism;Vitamin digestion and absorption
11146,0,0,0,4,0,0,1,0,0,1,0,0,"GLMN;glomulin, FKBP associated protein",GO:0031461//cullin-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005622//intracellular;GO:0031463//Cul3-RING ubiquitin ligase complex,"GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042327//positive regulation of phosphorylation;GO:0001570//vasculogenesis;GO:0001843//neural tube closure;GO:0042692//muscle cell differentiation;GO:0050715//positive regulation of cytokine secretion;GO:0042130//negative regulation of T cell proliferation;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0040029//regulation of gene expression, epigenetic;GO:0031397//negative regulation of protein ubiquitination",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0005171//hepatocyte growth factor receptor binding;GO:0055105//ubiquitin-protein transferase inhibitor activity,-
11147,0,0,0,0,0,0,20,0,1,0,0,0,HHLA3;HERV-H LTR-associating 3,-,-,GO:0005515//protein binding,-
11148,9,0,0,0,1,0,12,0,4,0,0,0,HHLA2;HERV-H LTR-associating 2,GO:0016021//integral component of membrane,GO:0042104//positive regulation of activated T cell proliferation;GO:0031295//T cell costimulation;GO:0001819//positive regulation of cytokine production,GO:0005515//protein binding,-
11149,20,0,23,0,0,22,42,0,0,0,0,0,BVES;blood vessel epicardial substance,GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0034446//substrate adhesion-dependent cell spreading;GO:0032314//regulation of Rac GTPase activity;GO:0090136//epithelial cell-cell adhesion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0040017//positive regulation of locomotion;GO:0016192//vesicle-mediated transport;GO:0043088//regulation of Cdc42 GTPase activity;GO:0042391//regulation of membrane potential;GO:0007517//muscle organ development;GO:0008360//regulation of cell shape;GO:0060931//sinoatrial node cell development;GO:0002027//regulation of heart rate;GO:0001921//positive regulation of receptor recycling,GO:0005198//structural molecule activity;GO:0030552//cAMP binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
11151,0,0,0,0,0,0,0,0,14,0,0,0,"CORO1A;coronin, actin binding protein, 1A",GO:0005884//actin filament;GO:0005634//nucleus;GO:0030864//cortical actin cytoskeleton;GO:0001772//immunological synapse;GO:0030027//lamellipodium;GO:0043234//protein complex;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0001891//phagocytic cup;GO:0045335//phagocytic vesicle;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane,GO:0051126//negative regulation of actin nucleation;GO:0030833//regulation of actin filament polymerization;GO:0050918//positive chemotaxis;GO:0045087//innate immune response;GO:0043029//T cell homeostasis;GO:0030036//actin cytoskeleton organization;GO:0001845//phagolysosome assembly;GO:0048873//homeostasis of number of cells within a tissue;GO:0006816//calcium ion transport;GO:0030335//positive regulation of cell migration;GO:0008360//regulation of cell shape;GO:0071353//cellular response to interleukin-4;GO:0031589//cell-substrate adhesion;GO:0042102//positive regulation of T cell proliferation;GO:0032796//uropod organization;GO:0006909//phagocytosis;GO:0030595//leukocyte chemotaxis;GO:0006928//cellular component movement;GO:0007015//actin filament organization,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity;GO:0051015//actin filament binding;GO:0008092//cytoskeletal protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0008022//protein C-terminus binding,K13882//Tuberculosis;Phagosome
11152,0,1,0,1,1,13,27,0,33,0,10,0,WDR45;WD repeat domain 45,-,GO:0008219//cell death;GO:0006914//autophagy,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00797//beta-Alanine metabolism;Metabolic pathways;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K11447//Transcriptional misregulation in cancer
11153,0,0,0,0,0,0,1,0,26,0,0,0,FICD;FIC domain containing,GO:0016021//integral component of membrane,GO:0018117//protein adenylylation;GO:0034259//negative regulation of Rho GTPase activity,GO:0005524//ATP binding;GO:0070733//protein adenylyltransferase activity,-
11154,84,0,0,0,8,22,1,131,37,0,7,0,"AP4S1;adaptor-related protein complex 4, sigma 1 subunit",GO:0005794//Golgi apparatus;GO:0005905//coated pit,GO:0015031//protein transport,GO:0008565//protein transporter activity;GO:0005215//transporter activity,K12403//Lysosome
11155,0,0,0,10,9,0,25,0,49,50,21,0,LDB3;LIM domain binding 3,GO:0048471//perinuclear region of cytoplasm;GO:0005856//cytoskeleton;GO:0030018//Z disc;GO:0031143//pseudopodium,GO:0045214//sarcomere organization,GO:0051371//muscle alpha-actinin binding;GO:0008092//cytoskeletal protein binding;GO:0005080//protein kinase C binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,K05760//Leukocyte transendothelial migration;VEGF signaling pathway;Focal adhesion;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Chemokine signaling pathway
11156,0,0,0,0,1,21,0,0,0,0,0,0,"PTP4A3;protein tyrosine phosphatase type IVA, member 3",GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004727//prenylated protein tyrosine phosphatase activity,-
11157,84,0,0,0,0,0,0,0,27,0,0,0,"LSM6;LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005681//spliceosomal complex;GO:0070062//extracellular vesicular exosome;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol,"GO:0006364//rRNA processing;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0008033//tRNA processing;GO:0006397//mRNA processing;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12625//RNA degradation;Spliceosome
11158,0,0,0,3,4,0,0,61,3,1,0,0,"RABL2B;RAB, member of RAS oncogene family-like 2B",-,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
11159,0,19,0,0,18,0,13,1,0,3,10,0,"RABL2A;RAB, member of RAS oncogene family-like 2A",-,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0003924//GTPase activity,-
1116,0,0,0,0,0,13,0,0,6,0,0,0,CHI3L1;chitinase 3-like 1 (cartilage glycoprotein-39),GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space,GO:0070555//response to interleukin-1;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response;GO:0071356//cellular response to tumor necrosis factor;GO:0070741//response to interleukin-6;GO:0034612//response to tumor necrosis factor;GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030324//lung development;GO:0009612//response to mechanical stimulus;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0045766//positive regulation of angiogenesis;GO:0006032//chitin catabolic process;GO:0051216//cartilage development;GO:0072606//interleukin-8 secretion,GO:0005201//extracellular matrix structural constituent;GO:0030246//carbohydrate binding;GO:0004568//chitinase activity;GO:0008061//chitin binding,K01183//Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Biosynthesis of secondary metabolites
11160,0,0,0,3,16,0,50,0,9,0,19,0,ERLIN2;ER lipid raft associated 2,GO:0005789//endoplasmic reticulum membrane;GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0008219//cell death,GO:0005515//protein binding,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
11161,0,0,0,0,12,0,0,0,10,0,13,0,C14orf1;chromosome 14 open reading frame 1,GO:0030133//transport vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0016126//sterol biosynthetic process,-,-
11162,0,0,43,0,0,19,11,0,0,0,0,0,NUDT6;nudix (nucleoside diphosphate linked moiety X)-type motif 6,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0008083//growth factor activity;GO:0016787//hydrolase activity,-
11163,0,0,0,0,0,9,11,0,0,0,0,0,NUDT4;nudix (nucleoside diphosphate linked moiety X)-type motif 4,GO:0005622//intracellular;GO:0005829//cytosol,GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction;GO:0009187//cyclic nucleotide metabolic process;GO:0046831//regulation of RNA export from nucleus;GO:0019935//cyclic-nucleotide-mediated signaling;GO:0019722//calcium-mediated signaling;GO:0044281//small molecule metabolic process;GO:0046907//intracellular transport,"GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0046872//metal ion binding;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0030515//snoRNA binding;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity",-
11164,35,2,0,6,2,0,0,19,10,0,34,278,NUDT5;nudix (nucleoside diphosphate linked moiety X)-type motif 5,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005829//cytosol;GO:0005634//nucleus,GO:0009117//nucleotide metabolic process;GO:0009191//ribonucleoside diphosphate catabolic process;GO:0019303//D-ribose catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0044281//small molecule metabolic process,GO:0017110//nucleoside-diphosphatase activity;GO:0030515//snoRNA binding;GO:0047631//ADP-ribose diphosphatase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0000287//magnesium ion binding,K13987//Purine metabolism
11165,0,0,0,0,0,0,0,0,12,10,0,0,NUDT3;nudix (nucleoside diphosphate linked moiety X)-type motif 3,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0071544//diphosphoinositol polyphosphate catabolic process;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0015961//diadenosine polyphosphate catabolic process;GO:0007267//cell-cell signaling,"GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity;GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0000287//magnesium ion binding;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity",-
11166,0,1,0,0,22,12,0,0,14,0,9,0,SOX21;SRY (sex determining region Y)-box 21,GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0048863//stem cell differentiation;GO:0001942//hair follicle development;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
11167,0,62,0,25,57,3,56,64,61,0,2,0,FSTL1;follistatin-like 1,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0042594//response to starvation;GO:0030509//BMP signaling pathway,GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0005515//protein binding,K04661//TGF-beta signaling pathway;K06254//ECM-receptor interaction
11168,109,31,22,55,97,0,49,148,23,0,92,1,PSIP1;PC4 and SFRS1 interacting protein 1,GO:0005634//nucleus;GO:0034399//nuclear periphery;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0005720//nuclear heterochromatin,"GO:0006979//response to oxidative stress;GO:0009408//response to heat;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0000395//mRNA 5'-splice site recognition;GO:0075713//establishment of integrated proviral latency;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0097100//supercoiled DNA binding;GO:0003682//chromatin binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0033613//activating transcription factor binding,"K00020//Valine, leucine and isoleucine degradation;Metabolic pathways;Pentose phosphate pathway;Glutathione metabolism"
11169,65,0,0,0,0,22,31,0,25,0,0,0,WDHD1;WD repeat and HMG-box DNA binding protein 1,"GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm",GO:0033044//regulation of chromosome organization;GO:0070829//heterochromatin maintenance;GO:0006396//RNA processing,GO:0005515//protein binding;GO:0003677//DNA binding;GO:0070063//RNA polymerase binding;GO:0003723//RNA binding;GO:0003682//chromatin binding,-
1117,0,0,0,0,0,0,0,0,16,0,0,0,CHI3L2;chitinase 3-like 2,GO:0005615//extracellular space,GO:0005975//carbohydrate metabolic process;GO:0006032//chitin catabolic process,GO:0008061//chitin binding;GO:0004568//chitinase activity;GO:0030246//carbohydrate binding,K01183//Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
11170,0,0,0,0,0,58,46,0,53,41,0,0,"FAM107A;family with sequence similarity 107, member A",GO:0043005//neuron projection;GO:0005634//nucleus,GO:0001558//regulation of cell growth,-,-
11171,0,54,28,24,96,0,0,0,14,0,0,0,STRAP;serine/threonine kinase receptor associated protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0005829//cytosol;GO:0034719//SMN-Sm protein complex;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0010633//negative regulation of epithelial cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030277//maintenance of gastrointestinal epithelium;GO:0000387//spliceosomal snRNP assembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation,GO:0005102//receptor binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K13137//RNA transport
11172,0,0,0,0,0,0,20,0,0,0,0,0,INSL6;insulin-like 6,GO:0005576//extracellular region,GO:0007286//spermatid development;GO:0030317//sperm motility;GO:0043066//negative regulation of apoptotic process;GO:0008584//male gonad development;GO:0009566//fertilization,GO:0005179//hormone activity,-
11173,30,0,0,0,0,34,46,17,65,0,19,0,"ADAMTS7;ADAM metallopeptidase with thrombospondin type 1 motif, 7",GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix,GO:0032331//negative regulation of chondrocyte differentiation;GO:0071347//cellular response to interleukin-1;GO:0071356//cellular response to tumor necrosis factor;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0071773//cellular response to BMP stimulus,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0005515//protein binding,-
11174,0,0,0,0,0,78,92,107,63,350,0,0,"ADAMTS6;ADAM metallopeptidase with thrombospondin type 1 motif, 6",GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
11177,0,50,78,37,99,0,59,0,55,179,51,0,"BAZ1A;bromodomain adjacent to zinc finger domain, 1A",GO:0000228//nuclear chromosome;GO:0016590//ACF complex;GO:0008623//CHRAC,"GO:0006261//DNA-dependent DNA replication;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling",GO:0008270//zinc ion binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding,-
11178,0,0,0,0,0,3,0,128,22,0,0,0,"LZTS1;leucine zipper, putative tumor suppressor 1",GO:0005829//cytosol;GO:0043197//dendritic spine;GO:0016324//apical plasma membrane;GO:0044297//cell body;GO:0005654//nucleoplasm;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0043198//dendritic shaft;GO:0045211//postsynaptic membrane,"GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression;GO:0048814//regulation of dendrite morphogenesis;GO:0006351//transcription, DNA-templated;GO:0006386//termination of RNA polymerase III transcription;GO:0006355//regulation of transcription, DNA-templated;GO:0016242//negative regulation of macroautophagy;GO:0007049//cell cycle;GO:0006383//transcription from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
11179,0,25,0,11,18,18,0,0,46,0,0,0,ZNF277;zinc finger protein 277,GO:0005634//nucleus,"GO:0070301//cellular response to hydrogen peroxide;GO:0006351//transcription, DNA-templated;GO:2000772//regulation of cellular senescence;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding,K11447//Transcriptional misregulation in cancer;K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
1118,0,0,0,0,0,0,48,0,47,71,10,328,CHIT1;chitinase 1 (chitotriosidase),GO:0005764//lysosome;GO:0005615//extracellular space,GO:0009617//response to bacterium;GO:0000272//polysaccharide catabolic process;GO:0006955//immune response;GO:0006032//chitin catabolic process,GO:0008061//chitin binding;GO:0004568//chitinase activity;GO:0008843//endochitinase activity,K01183//Metabolic pathways;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism
11180,11,71,3,117,196,0,0,11,54,1,148,0,WDR6;WD repeat domain 6,GO:0005737//cytoplasm;GO:0008180//COP9 signalosome;GO:0005886//plasma membrane,GO:0010507//negative regulation of autophagy;GO:0008285//negative regulation of cell proliferation;GO:0007050//cell cycle arrest,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K03130//Herpes simplex infection;Basal transcription factors
11182,1,0,0,0,0,40,23,0,21,112,0,690,"SLC2A6;solute carrier family 2 (facilitated glucose transporter), member 6",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0015758//glucose transport;GO:0055085//transmembrane transport,GO:0005355//glucose transmembrane transporter activity,-
11183,68,1,0,17,32,12,0,0,18,0,13,0,MAP4K5;mitogen-activated protein kinase kinase kinase kinase 5,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007257//activation of JUN kinase activity,GO:0005524//ATP binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0004672//protein kinase activity,-
11184,0,0,0,0,0,11,7,58,29,0,0,0,MAP4K1;mitogen-activated protein kinase kinase kinase kinase 1,GO:0016020//membrane,GO:0018105//peptidyl-serine phosphorylation;GO:0046777//protein autophosphorylation;GO:0000185//activation of MAPKKK activity;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0007257//activation of JUN kinase activity;GO:0008283//cell proliferation,GO:0005083//small GTPase regulator activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0008349//MAP kinase kinase kinase kinase activity,K04408//MAPK signaling pathway
11185,181,0,0,0,3,0,0,0,0,0,0,0,INMT;indolethylamine N-methyltransferase,GO:0005829//cytosol,GO:0009308//amine metabolic process;GO:0009636//response to toxic substance;GO:0032259//methylation,GO:0004790//thioether S-methyltransferase activity;GO:0030748//amine N-methyltransferase activity,K00562//Selenocompound metabolism;Tryptophan metabolism
11186,0,0,0,0,1,0,0,55,11,0,13,0,RASSF1;Ras association (RalGDS/AF-6) domain family member 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005886//plasma membrane,GO:0006974//cellular response to DNA damage stimulus;GO:0050821//protein stabilization;GO:0007050//cell cycle arrest;GO:0031398//positive regulation of protein ubiquitination;GO:0007265//Ras protein signal transduction;GO:0071157//negative regulation of cell cycle arrest,GO:0047485//protein N-terminus binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K09850//Pathways in cancer;Non-small cell lung cancer;Bladder cancer
11187,0,1,0,0,0,0,1,147,37,0,0,0,PKP3;plakophilin 3,GO:0030057//desmosome;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005634//nucleus,GO:0090002//establishment of protein localization to plasma membrane;GO:0002159//desmosome assembly;GO:0016337//single organismal cell-cell adhesion,GO:0050839//cell adhesion molecule binding,K12642//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
11188,0,0,0,0,21,30,8,0,68,182,0,1,NISCH;nischarin,GO:0055037//recycling endosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005769//early endosome;GO:0005886//plasma membrane,"GO:0032228//regulation of synaptic transmission, GABAergic;GO:0030036//actin cytoskeleton organization;GO:0006915//apoptotic process;GO:0008217//regulation of blood pressure;GO:0048243//norepinephrine secretion;GO:0030336//negative regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006006//glucose metabolic process;GO:0016601//Rac protein signal transduction",GO:0042802//identical protein binding;GO:0008227//G-protein coupled amine receptor activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0035091//phosphatidylinositol binding,K10411//Huntington's disease
11189,0,0,0,1,0,21,34,0,32,73,15,0,"CELF3;CUGBP, Elav-like family member 3",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0030317//sperm motility;GO:0007283//spermatogenesis;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding,-
1119,0,0,1,18,8,0,0,0,4,0,0,0,CHKA;choline kinase alpha,GO:0005829//cytosol,GO:0006869//lipid transport;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0019695//choline metabolic process;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006629//lipid metabolic process,GO:0004305//ethanolamine kinase activity;GO:0042803//protein homodimerization activity;GO:0033265//choline binding;GO:0004103//choline kinase activity;GO:0004871//signal transducer activity;GO:0005524//ATP binding;GO:0008144//drug binding;GO:0004104//cholinesterase activity,K14156//Glycerophospholipid metabolism;Metabolic pathways
11190,112,0,0,6,7,25,0,0,58,80,14,76,CEP250;centrosomal protein 250kDa,GO:0070062//extracellular vesicular exosome;GO:0031616//spindle pole centrosome;GO:0005813//centrosome;GO:0043234//protein complex;GO:0005929//cilium;GO:0005814//centriole;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005815//microtubule organizing center,GO:0030997//regulation of centriole-centriole cohesion;GO:0000278//mitotic cell cycle;GO:0033365//protein localization to organelle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0010457//centriole-centriole cohesion;GO:0008104//protein localization,GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,-
11191,0,0,0,2,38,0,16,0,0,0,16,0,PTENP1;phosphatase and tensin homolog pseudogene 1 (functional),-,-,-,K01110//Prostate cancer;Small cell lung cancer;Pathways in cancer;Phosphatidylinositol signaling system;Tight junction;Glioma;p53 signaling pathway;Focal adhesion;Inositol phosphate metabolism;Endometrial cancer;Melanoma
11193,0,0,0,0,34,0,0,0,2,0,0,0,WBP4;WW domain binding protein 4,GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0045292//mRNA cis splicing, via spliceosome",GO:0003676//nucleic acid binding;GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
11194,0,0,0,0,0,2,31,0,61,0,0,7,"ABCB8;ATP-binding cassette, sub-family B (MDR/TAP), member 8",GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016020//membrane;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0016021//integral component of membrane;GO:0005740//mitochondrial envelope,GO:0006810//transport;GO:0006200//ATP catabolic process;GO:0055085//transmembrane transport,"GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05655//ABC transporters
11196,0,24,0,37,292,1,0,0,47,0,0,0,SEC23IP;SEC23 interacting protein,GO:0005801//cis-Golgi network;GO:0043231//intracellular membrane-bounded organelle;GO:0070971//endoplasmic reticulum exit site;GO:0012507//ER to Golgi transport vesicle membrane;GO:0097038//perinuclear endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0001675//acrosome assembly;GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0007338//single fertilization,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
11197,102,0,0,0,0,1,5,0,21,4,9,161,WIF1;WNT inhibitory factor 1,GO:0005576//extracellular region,GO:0016055//Wnt signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0007165//signal transduction;GO:0007275//multicellular organismal development,GO:0005515//protein binding,K01691//Wnt signaling pathway
11198,0,90,0,69,136,45,37,55,47,0,12,0,SUPT16H;suppressor of Ty 16 homolog (S. cerevisiae),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005694//chromosome,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0010467//gene expression;GO:0006337//nucleosome disassembly;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0050434//positive regulation of viral transcription",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
11199,63,0,0,0,0,0,0,0,34,0,10,0,ANXA10;annexin A10,GO:0005739//mitochondrion,-,GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,-
112,0,0,0,1,0,11,8,61,85,13,5,0,ADCY6;adenylate cyclase 6,GO:0005886//plasma membrane;GO:0005929//cilium;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007212//dopamine receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007202//activation of phospholipase C activity;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0010977//negative regulation of neuron projection development;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0071870//cellular response to catecholamine stimulus;GO:0006833//water transport;GO:0007165//signal transduction;GO:0034199//activation of protein kinase A activity,GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding,K08046//Cholinergic synapse;HTLV-I infection;GABAergic synapse;Salivary secretion;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Endocrine and other factor-regulated calcium reabsorption;Melanogenesis;Bile secretion;Gastric acid secretion;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Progesterone-mediated oocyte maturation;Pancreatic secretion;Vascular smooth muscle contraction;Vasopressin-regulated water reabsorption;Morphine addiction;Oocyte meiosis;Taste transduction;Glutamatergic synapse;Purine metabolism
11200,0,0,0,5,0,0,14,0,15,0,9,0,CHEK2;checkpoint kinase 2,"GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0016605//PML body","GO:0045893//positive regulation of transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:0006355//regulation of transcription, DNA-templated;GO:0044257//cellular protein catabolic process;GO:0010332//response to gamma radiation;GO:0006351//transcription, DNA-templated;GO:0072428//signal transduction involved in intra-S DNA damage checkpoint;GO:0050821//protein stabilization;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006974//cellular response to DNA damage stimulus;GO:0006302//double-strand break repair;GO:0046777//protein autophosphorylation;GO:0042770//signal transduction in response to DNA damage;GO:0090399//replicative senescence;GO:0006975//DNA damage induced protein phosphorylation;GO:0042176//regulation of protein catabolic process;GO:0006468//protein phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0090307//spindle assembly involved in mitosis",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding,K06641//HTLV-I infection;p53 signaling pathway;Cell cycle - yeast;Cell cycle
11201,0,0,0,13,20,14,0,0,97,0,0,0,POLI;polymerase (DNA directed) iota,GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006281//DNA repair;GO:0006261//DNA-dependent DNA replication,GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding,K03510//Fanconi anemia pathway
11202,0,0,0,0,0,0,0,0,24,0,0,0,KLK8;kallikrein-related peptidase 8,GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0009611//response to wounding;GO:0031642//negative regulation of myelination;GO:0007613//memory;GO:0048812//neuron projection morphogenesis;GO:0043616//keratinocyte proliferation;GO:0048681//negative regulation of axon regeneration;GO:0006508//proteolysis;GO:0050808//synapse organization;GO:0050807//regulation of synapse organization,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,-
11209,60,0,63,0,3,43,2,18,50,0,25,0,MST1P2;macrophage stimulating 1 (hepatocyte growth factor-like) pseudogene 2,-,-,-,K05460//Renal cell carcinoma;Focal adhesion;Melanoma;Cytokine-cytokine receptor interaction;Malaria;Pathways in cancer
1121,0,0,0,14,70,0,10,48,7,0,6,0,CHM;choroideremia (Rab escort protein 1),GO:0005968//Rab-protein geranylgeranyltransferase complex;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0018344//protein geranylgeranylation;GO:0007601//visual perception;GO:0006612//protein targeting to membrane;GO:0050896//response to stimulus;GO:0001568//blood vessel development,GO:0005096//GTPase activator activity;GO:0017137//Rab GTPase binding;GO:0004663//Rab geranylgeranyltransferase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
11211,0,0,0,0,0,0,0,0,0,0,10,0,FZD10;frizzled class receptor 10,GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0042995//cell projection;GO:0005737//cytoplasm,GO:0071300//cellular response to retinoic acid;GO:0034259//negative regulation of Rho GTPase activity;GO:0060070//canonical Wnt signaling pathway;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0032855//positive regulation of Rac GTPase activity;GO:0008406//gonad development;GO:0030182//neuron differentiation;GO:0001944//vasculature development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007420//brain development;GO:0032956//regulation of actin cytoskeleton organization,GO:0004930//G-protein coupled receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding,K02842//Wnt signaling pathway;HTLV-I infection;Pathways in cancer;Melanogenesis;Basal cell carcinoma
11212,0,0,0,10,10,20,0,0,14,0,0,0,PROSC;proline synthetase co-transcribed homolog (bacterial),GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005737//cytoplasm,GO:1901605//alpha-amino acid metabolic process,GO:0030170//pyridoxal phosphate binding,-
11213,0,0,0,0,0,6,20,0,12,0,0,0,IRAK3;interleukin-1 receptor-associated kinase 3,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042177//negative regulation of protein catabolic process;GO:0045824//negative regulation of innate immune response;GO:0006468//protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032494//response to peptidoglycan;GO:0046777//protein autophosphorylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0070555//response to interleukin-1;GO:0070498//interleukin-1-mediated signaling pathway;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0032695//negative regulation of interleukin-12 production;GO:0043330//response to exogenous dsRNA;GO:0032496//response to lipopolysaccharide;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0010936//negative regulation of macrophage cytokine production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0010933//positive regulation of macrophage tolerance induction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043242//negative regulation of protein complex disassembly,GO:0004674//protein serine/threonine kinase activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K04732//Neurotrophin signaling pathway;Apoptosis
11214,0,17,24,31,88,20,25,22,59,0,28,0,AKAP13;A kinase (PRKA) anchor protein 13,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane,GO:1900169//regulation of glucocorticoid mediated signaling pathway;GO:0051168//nuclear export;GO:0006468//protein phosphorylation;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0010611//regulation of cardiac muscle hypertrophy;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0045859//regulation of protein kinase activity,GO:0032947//protein complex scaffold;GO:0051018//protein kinase A binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004691//cAMP-dependent protein kinase activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0017048//Rho GTPase binding;GO:0004871//signal transducer activity,K12791//Pathogenic Escherichia coli infection
11215,364,35,0,40,113,54,26,0,67,100,20,1,AKAP11;A kinase (PRKA) anchor protein 11,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,GO:0035556//intracellular signal transduction,GO:0008157//protein phosphatase 1 binding;GO:0051018//protein kinase A binding,-
11216,0,0,0,16,4,34,76,0,9,0,0,0,AKAP10;A kinase (PRKA) anchor protein 10,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007596//blood coagulation;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0008104//protein localization,-,-
11217,0,0,0,0,0,0,3,0,0,0,0,0,AKAP2;A kinase (PRKA) anchor protein 2,-,-,-,-
11218,0,0,0,18,37,0,29,120,38,0,8,0,DDX20;DEAD (Asp-Glu-Ala-Asp) box polypeptide 20,GO:0005829//cytosol;GO:0005634//nucleus;GO:0017053//transcriptional repressor complex;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0005654//nucleoplasm,GO:0043065//positive regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0048477//oogenesis;GO:0010467//gene expression;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0016070//RNA metabolic process;GO:0006200//ATP catabolic process;GO:0006396//RNA processing;GO:0050810//regulation of steroid biosynthetic process,GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005515//protein binding,K13131//RNA transport
11219,0,0,0,0,0,0,0,0,13,0,0,0,TREX2;three prime repair exonuclease 2,GO:0005634//nucleus,"GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0000738//DNA catabolic process, exonucleolytic",GO:0008853//exodeoxyribonuclease III activity;GO:0042803//protein homodimerization activity;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0000287//magnesium ion binding;GO:0003676//nucleic acid binding,-
1122,0,0,0,14,25,32,47,0,13,0,0,0,CHML;choroideremia-like (Rab escort protein 2),GO:0005968//Rab-protein geranylgeranyltransferase complex;GO:0005829//cytosol,GO:0006886//intracellular protein transport;GO:0018344//protein geranylgeranylation;GO:0043547//positive regulation of GTPase activity,GO:0004663//Rab geranylgeranyltransferase activity;GO:0017137//Rab GTPase binding;GO:0005096//GTPase activator activity,-
11221,0,0,0,0,0,0,0,104,33,0,0,0,DUSP10;dual specificity phosphatase 10,GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0048709//oligodendrocyte differentiation;GO:0007254//JNK cascade;GO:0000188//inactivation of MAPK activity;GO:0032496//response to lipopolysaccharide;GO:0043508//negative regulation of JUN kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0002819//regulation of adaptive immune response;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0006950//response to stress;GO:0046329//negative regulation of JNK cascade,GO:0033549//MAP kinase phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0016791//phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity,K04459//Transcriptional misregulation in cancer;Serotonergic synapse;MAPK signaling pathway
11222,0,48,1,0,179,19,0,1,6,0,2,0,MRPL3;mitochondrial ribosomal protein L3,GO:0005762//mitochondrial large ribosomal subunit,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,-
11223,86,0,0,3,30,94,0,1,124,0,5,0,MST1L;macrophage stimulating 1-like,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K05460//Focal adhesion;Renal cell carcinoma;Cytokine-cytokine receptor interaction;Melanoma;Pathways in cancer;Malaria
11224,0,90,0,10,69,0,0,0,1,0,1,0,RPL35;ribosomal protein L35,GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016032//viral process",GO:0003735//structural constituent of ribosome;GO:0003729//mRNA binding;GO:0044822//poly(A) RNA binding,K02918//Ribosome
11226,0,0,0,0,0,19,36,53,80,0,0,0,GALNT6;polypeptide N-acetylgalactosaminyltransferase 6,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006493//protein O-linked glycosylation,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
11227,0,0,0,0,0,0,0,0,35,0,0,0,GALNT5;polypeptide N-acetylgalactosaminyltransferase 5,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006024//glycosaminoglycan biosynthetic process,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
11228,0,60,0,52,162,36,1,0,36,0,0,0,RASSF8;Ras association (RalGDS/AF-6) domain family (N-terminal) member 8,-,GO:0007165//signal transduction,-,-
1123,6,0,0,0,15,18,0,0,18,178,0,0,CHN1;chimerin 1,GO:0005829//cytosol,GO:0050770//regulation of axonogenesis;GO:0008045//motor neuron axon guidance;GO:0032314//regulation of Rac GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0046872//metal ion binding;GO:0046875//ephrin receptor binding;GO:0005096//GTPase activator activity;GO:0005070//SH3/SH2 adaptor activity,K02649//Endometrial cancer;Toxoplasmosis;Osteoclast differentiation;Glioma;Focal adhesion;VEGF signaling pathway;Bacterial invasion of epithelial cells;HTLV-I infection;Jak-STAT signaling pathway;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Apoptosis;mTOR signaling pathway;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;Chemokine signaling pathway;Pathways in cancer;Pancreatic cancer;Toll-like receptor signaling pathway;Influenza A;Non-small cell lung cancer;Hepatitis C;Melanoma;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Measles;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Acute myeloid leukemia;Cholinergic synapse;B cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Chronic myeloid leukemia;Type II diabetes mellitus;Amoebiasis;Colorectal cancer;Phosphatidylinositol signaling system;Insulin signaling pathway;Prostate cancer;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;K04450//Dopaminergic synapse;Cocaine addiction;HTLV-I infection;Alcoholism;Influenza A;Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;K13736//Bacterial invasion of epithelial cells
11230,0,0,0,0,0,0,0,0,35,0,0,0,"PRAF2;PRA1 domain family, member 2",GO:0016021//integral component of membrane;GO:0010008//endosome membrane,GO:0015813//L-glutamate transport;GO:0015031//protein transport,-,-
11231,0,0,0,26,32,0,16,0,116,84,0,0,SEC63;SEC63 homolog (S. cerevisiae),GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0006612//protein targeting to membrane;GO:0001889//liver development;GO:0072001//renal system development;GO:0010259//multicellular organismal aging;GO:0006807//nitrogen compound metabolic process;GO:0031204//posttranslational protein targeting to membrane, translocation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006620//posttranslational protein targeting to membrane",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0008565//protein transporter activity,K09540//Protein export;Protein processing in endoplasmic reticulum
11232,0,0,0,7,18,0,0,0,76,0,10,0,"POLG2;polymerase (DNA directed), gamma 2, accessory subunit",GO:0070062//extracellular vesicular exosome;GO:0000262//mitochondrial chromosome;GO:0042645//mitochondrial nucleoid,GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0006261//DNA-dependent DNA replication,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0042802//identical protein binding,K02333//Metabolic pathways
11234,0,9,0,10,0,39,15,0,70,0,15,0,HPS5;Hermansky-Pudlak syndrome 5,GO:0031084//BLOC-2 complex,GO:0006996//organelle organization;GO:0043473//pigmentation;GO:0007596//blood coagulation,-,-
11235,0,0,0,8,27,0,0,0,23,0,0,0,PDCD10;programmed cell death 10,GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0008284//positive regulation of cell proliferation;GO:0006915//apoptotic process;GO:0001525//angiogenesis;GO:0043066//negative regulation of apoptotic process;GO:0043406//positive regulation of MAP kinase activity,GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
11236,0,22,0,1,0,24,0,0,15,0,0,0,RNF139;ring finger protein 139,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0017148//negative regulation of translation;GO:0070613//regulation of protein processing;GO:0016567//protein ubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0031396//regulation of protein ubiquitination;GO:0060628//regulation of ER to Golgi vesicle-mediated transport,GO:0019787//small conjugating protein ligase activity;GO:0004872//receptor activity;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
11237,0,0,0,0,7,0,0,0,0,0,0,0,RNF24;ring finger protein 24,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,-,GO:0008270//zinc ion binding,-
11238,5,0,0,13,35,0,2,0,22,0,0,0,"CA5B;carbonic anhydrase VB, mitochondrial",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0015701//bicarbonate transport;GO:0044281//small molecule metabolic process;GO:0006730//one-carbon metabolic process,GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding,K01672//Collecting duct acid secretion;Pancreatic secretion;Nitrogen metabolism;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion
112398,0,0,1,0,0,0,0,0,1,0,0,0,EGLN2;egl-9 family hypoxia-inducible factor 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0045732//positive regulation of protein catabolic process;GO:0071456//cellular response to hypoxia;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0001558//regulation of cell growth;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0045454//cell redox homeostasis;GO:0001666//response to hypoxia;GO:0043523//regulation of neuron apoptotic process;GO:0055114//oxidation-reduction process;GO:0030520//intracellular estrogen receptor signaling pathway,"GO:0031418//L-ascorbic acid binding;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005515//protein binding;GO:0019826//oxygen sensor activity;GO:0008198//ferrous iron binding",K09592//Pathways in cancer;Renal cell carcinoma
112399,0,0,0,0,0,20,4,0,0,0,0,0,EGLN3;egl-9 family hypoxia-inducible factor 3,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042127//regulation of cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0055114//oxidation-reduction process;GO:0043523//regulation of neuron apoptotic process;GO:0001666//response to hypoxia;GO:0006915//apoptotic process,GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding,K09592//Pathways in cancer;Renal cell carcinoma
1124,0,0,36,7,11,38,17,0,13,0,9,0,CHN2;chimerin 2,GO:0016020//membrane;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0009967//positive regulation of signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005070//SH3/SH2 adaptor activity;GO:0005096//GTPase activator activity,K02649//Acute myeloid leukemia;Cholinergic synapse;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;Melanoma;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Hepatitis C;Non-small cell lung cancer;Measles;Insulin signaling pathway;Phosphatidylinositol signaling system;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Prostate cancer;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Colorectal cancer;Amoebiasis;Type II diabetes mellitus;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;Toxoplasmosis;Osteoclast differentiation;Endometrial cancer;VEGF signaling pathway;Focal adhesion;Glioma;Pancreatic cancer;Pathways in cancer;Chemokine signaling pathway;Influenza A;Toll-like receptor signaling pathway;mTOR signaling pathway;Apoptosis;Epstein-Barr virus infection;Renal cell carcinoma;ErbB signaling pathway;K04450//Alcoholism;Influenza A;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;Epstein-Barr virus infection;Amphetamine addiction;MAPK signaling pathway;K13736//Bacterial invasion of epithelial cells;K06068//T cell receptor signaling pathway;Adipocytokine signaling pathway;Vascular smooth muscle contraction;Neurotrophin signaling pathway;Measles;Type II diabetes mellitus;GnRH signaling pathway;Chemokine signaling pathway;Tight junction;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis
11240,0,0,0,0,0,9,1,0,64,0,0,0,"PADI2;peptidyl arginine deiminase, type II",GO:0070062//extracellular vesicular exosome;GO:0035327//transcriptionally active chromatin;GO:0005737//cytoplasm,GO:0018101//protein citrullination;GO:1901624//negative regulation of lymphocyte chemotaxis;GO:0021762//substantia nigra development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0048096//chromatin-mediated maintenance of transcription;GO:0010848//regulation of chromatin disassembly;GO:0036413//histone H3-R26 citrullination,GO:0004668//protein-arginine deiminase activity;GO:0030331//estrogen receptor binding;GO:0005509//calcium ion binding,-
11243,0,0,0,0,13,0,0,0,12,0,0,0,PMF1;polyamine-modulated factor 1,GO:0005829//cytosol;GO:0005667//transcription factor complex;GO:0000444//MIS12/MIND type complex;GO:0005634//nucleus,"GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0043522//leucine zipper domain binding;GO:0005515//protein binding,-
11244,0,39,1,32,98,19,0,0,37,0,0,0,ZHX1;zinc fingers and homeoboxes 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
11245,2,0,0,29,96,6,0,0,24,0,0,0,GPR176;G protein-coupled receptor 176,GO:0005887//integral component of plasma membrane,GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
112464,0,0,0,0,0,0,36,87,10,0,0,0,"PRKCDBP;protein kinase C, delta binding protein",GO:0043234//protein complex;GO:0005901//caveola,GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030866//cortical actin cytoskeleton organization;GO:0051898//negative regulation of protein kinase B signaling,GO:0005080//protein kinase C binding;GO:0005515//protein binding,-
11247,0,1,0,0,0,0,0,0,0,0,4,0,NXPH4;neurexophilin 4,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway,-,-
112476,0,0,3,0,0,0,0,0,8,0,1,0,PRRT2;proline-rich transmembrane protein 2,GO:0045202//synapse;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0009607//response to biotic stimulus;GO:0050884//neuromuscular process controlling posture,-,-
112479,0,109,2,344,259,46,40,1,24,0,364,0,ERI2;ERI1 exoribonuclease family member 2,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0003676//nucleic acid binding;GO:0004527//exonuclease activity;GO:0008270//zinc ion binding,-
11248,73,0,0,0,0,5,0,0,41,0,0,0,NXPH3;neurexophilin 3,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway,GO:0005102//receptor binding,-
112483,36,1,0,9,30,17,0,0,0,0,0,0,SAT2;spermidine/spermine N1-acetyltransferase family member 2,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0046204//nor-spermidine metabolic process;GO:0032918//spermidine acetylation;GO:0032920//putrescine acetylation;GO:0032919//spermine acetylation;GO:0009447//putrescine catabolic process,GO:0004145//diamine N-acetyltransferase activity,K00657//Arginine and proline metabolism;ABC transporters;Metabolic pathways
112487,0,11,0,1,30,0,11,0,53,0,0,0,DTD2;D-tyrosyl-tRNA deacylase 2 (putative),GO:0005737//cytoplasm,GO:0019478//D-amino acid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0005515//protein binding",K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
11249,0,0,0,0,0,3,0,0,1,0,0,0,NXPH2;neurexophilin 2,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway,-,-
112495,0,122,1,104,214,0,0,1,4,0,3,588,"GTF3C6;general transcription factor IIIC, polypeptide 6, alpha 35kDa",GO:0000127//transcription factor TFIIIC complex,"GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0042797//tRNA transcription from RNA polymerase III promoter",GO:0005515//protein binding;GO:0003677//DNA binding,-
11250,0,0,0,15,0,0,0,0,0,0,0,0,GPR45;G protein-coupled receptor 45,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
11251,0,19,0,0,0,23,23,58,24,0,0,0,PTGDR2;prostaglandin D2 receptor 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006955//immune response;GO:0019722//calcium-mediated signaling;GO:0006935//chemotaxis;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004958//prostaglandin F receptor activity;GO:0001785//prostaglandin J receptor activity;GO:0004956//prostaglandin D receptor activity;GO:0004930//G-protein coupled receptor activity,-
11252,0,57,16,27,116,0,0,96,27,0,26,0,PACSIN2;protein kinase C and casein kinase substrate in neurons 2,GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0055038//recycling endosome membrane;GO:0032587//ruffle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005901//caveola;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0030659//cytoplasmic vesicle membrane;GO:0005856//cytoskeleton;GO:0019898//extrinsic component of membrane;GO:0005911//cell-cell junction;GO:0005737//cytoplasm,GO:0030036//actin cytoskeleton organization;GO:0036010//protein localization to endosome;GO:0097320//membrane tubulation;GO:0072584//caveolin-mediated endocytosis;GO:0048858//cell projection morphogenesis;GO:0070836//caveola assembly;GO:0045806//negative regulation of endocytosis,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0070300//phosphatidic acid binding;GO:0005215//transporter activity;GO:0008092//cytoskeletal protein binding,K12804//NOD-like receptor signaling pathway;K10408//Huntington's disease;K04705//Endocytosis;Jak-STAT signaling pathway;K06106//Shigellosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction
11253,0,0,0,0,0,32,5,49,15,0,0,0,"MAN1B1;mannosidase, alpha, class 1B, member 1",GO:0031982//vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0044322//endoplasmic reticulum quality control compartment;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0006487//protein N-linked glycosylation;GO:0009311//oligosaccharide metabolic process;GO:0043687//post-translational protein modification;GO:0006457//protein folding,"GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",K01230//N-Glycan biosynthesis;Protein processing in endoplasmic reticulum;Various types of N-glycan biosynthesis;Metabolic pathways
11254,0,0,0,0,0,36,0,0,40,0,8,0,"SLC6A14;solute carrier family 6 (amino acid transporter), member 14",GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle,GO:0009636//response to toxic substance;GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0006520//cellular amino acid metabolic process;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006810//transport,GO:0015171//amino acid transmembrane transporter activity;GO:0005328//neurotransmitter:sodium symporter activity,-
11255,0,0,0,0,0,19,0,0,9,0,0,0,HRH3;histamine receptor H3,GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0043209//myelin sheath;GO:0005887//integral component of plasma membrane,"GO:0007612//learning;GO:0007269//neurotransmitter secretion;GO:0014061//regulation of norepinephrine secretion;GO:0007420//brain development;GO:0007194//negative regulation of adenylate cyclase activity;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0014050//negative regulation of glutamate secretion;GO:0014063//negative regulation of serotonin secretion;GO:0042755//eating behavior;GO:0045776//negative regulation of blood pressure;GO:0014053//negative regulation of gamma-aminobutyric acid secretion;GO:0007613//memory;GO:0042756//drinking behavior;GO:0014070//response to organic cyclic compound",GO:0008144//drug binding;GO:0004969//histamine receptor activity,K04151//Neuroactive ligand-receptor interaction
112574,240,0,0,37,54,0,41,0,24,0,13,0,SNX18;sorting nexin 18,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0030659//cytoplasmic vesicle membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0030426//growth cone;GO:0043025//neuronal cell body,GO:0007067//mitotic nuclear division;GO:0006886//intracellular protein transport;GO:0043547//positive regulation of GTPase activity;GO:0016197//endosomal transport;GO:0036089//cleavage furrow formation;GO:0006897//endocytosis;GO:0000281//mitotic cytokinesis,"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K11247//Endocytosis
11258,0,0,1,12,3,0,0,0,27,0,2,0,DCTN3;dynactin 3 (p22),GO:0005829//cytosol;GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0000777//condensed chromosome kinetochore;GO:0032154//cleavage furrow;GO:0005869//dynactin complex;GO:0005819//spindle;GO:0005813//centrosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0000910//cytokinesis;GO:0007017//microtubule-based process;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0005515//protein binding;GO:0005198//structural molecule activity,-
11259,0,0,0,0,0,71,0,0,63,0,0,0,FILIP1L;filamin A interacting protein 1-like,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12478//Tuberculosis;Endocytosis;Phagosome;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K06267//ECM-receptor interaction
11260,0,33,1,67,119,26,34,0,30,149,0,213,"XPOT;exportin, tRNA",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0005654//nucleoplasm,GO:0006409//tRNA export from nucleus;GO:0006886//intracellular protein transport,GO:0008536//Ran GTPase binding;GO:0000049//tRNA binding,K14288//RNA transport
112609,0,0,0,0,0,16,0,0,7,0,0,0,MRAP2;melanocortin 2 receptor accessory protein 2,GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0030819//positive regulation of cAMP biosynthetic process;GO:0034394//protein localization to cell surface;GO:0007631//feeding behavior;GO:0097009//energy homeostasis;GO:0006112//energy reserve metabolic process,GO:0070996//type 1 melanocortin receptor binding;GO:0031783//type 5 melanocortin receptor binding;GO:0031780//corticotropin hormone receptor binding;GO:0042802//identical protein binding;GO:0031781//type 3 melanocortin receptor binding;GO:0005515//protein binding;GO:0031782//type 4 melanocortin receptor binding,-
11261,0,24,26,36,223,0,10,0,73,0,0,0,CHP1;calcineurin-like EF-hand protein 1,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0051222//positive regulation of protein transport;GO:0022406//membrane docking;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0031397//negative regulation of protein ubiquitination;GO:0031953//negative regulation of protein autophosphorylation;GO:0061024//membrane organization;GO:0006611//protein export from nucleus;GO:0071468//cellular response to acidic pH;GO:0006469//negative regulation of protein kinase activity;GO:0042308//negative regulation of protein import into nucleus;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0045056//transcytosis;GO:0007264//small GTPase mediated signal transduction;GO:0090314//positive regulation of protein targeting to membrane;GO:0010923//negative regulation of phosphatase activity;GO:0051259//protein oligomerization;GO:0050821//protein stabilization;GO:0031122//cytoplasmic microtubule organization;GO:0051453//regulation of intracellular pH;GO:0061025//membrane fusion;GO:0060050//positive regulation of protein glycosylation;GO:0006813//potassium ion transport;GO:0001933//negative regulation of protein phosphorylation;GO:0017156//calcium ion-dependent exocytosis;GO:0001578//microtubule bundle formation,GO:0008017//microtubule binding;GO:0015459//potassium channel regulator activity;GO:0005215//transporter activity;GO:0019900//kinase binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity,K06268//Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;T cell receptor signaling pathway;Apoptosis;Amphetamine addiction;Glutamatergic synapse;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Long-term potentiation;Tuberculosis;Axon guidance;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation;B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection
112611,0,18,2,14,73,0,18,64,0,0,1,0,RWDD2A;RWD domain containing 2A,-,-,-,-
112616,0,0,0,0,0,13,0,0,13,0,0,0,CMTM7;CKLF-like MARVEL transmembrane domain containing 7,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
11262,143,0,0,0,0,0,0,41,59,0,11,0,SP140;SP140 nuclear body protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006952//defense response",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K15413//Herpes simplex infection
11264,5,0,0,7,29,0,37,0,26,0,14,0,"PXMP4;peroxisomal membrane protein 4, 24kDa",GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K13350//Peroxisome
11266,0,0,0,0,14,0,0,0,0,0,12,0,DUSP12;dual specificity phosphatase 12,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006464//cellular protein modification process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0033133//positive regulation of glucokinase activity,GO:0008270//zinc ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019900//kinase binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
11267,35,28,0,22,49,0,0,0,0,0,13,0,"SNF8;SNF8, ESCRT-II complex subunit",GO:0031902//late endosome membrane;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0006351//transcription, DNA-templated;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0061024//membrane organization",GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K12188//Endocytosis
11269,0,30,0,7,21,19,15,1,8,0,47,0,DDX19B;DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0005635//nuclear envelope,GO:0006406//mRNA export from nucleus;GO:0015031//protein transport,GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0004386//helicase activity,K13025//RNA transport;mRNA surveillance pathway;Spliceosome;K03257//RNA transport;K01529//Purine metabolism
112703,5,47,53,26,91,11,4,0,7,0,70,0,"FAM71E1;family with sequence similarity 71, member E1",-,-,-,-
112714,0,0,21,0,6,10,0,0,21,0,3,0,"TUBA3E;tubulin, alpha 3e",GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0007017//microtubule-based process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton,K07374//Gap junction;Phagosome;Pathogenic Escherichia coli infection
112724,0,0,0,0,0,0,28,0,0,0,15,0,RDH13;retinol dehydrogenase 13 (all-trans/9-cis),GO:0005739//mitochondrion,GO:0042462//eye photoreceptor cell development;GO:0010842//retina layer formation;GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
11273,107,38,0,8,12,13,44,5,32,1,8,0,ATXN2L;ataxin 2-like,GO:0016020//membrane;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule,GO:0010603//regulation of cytoplasmic mRNA processing body assembly;GO:0034063//stress granule assembly,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
11274,0,0,0,0,18,2,0,2,54,0,6,0,USP18;ubiquitin specific peptidase 18,GO:0005829//cytosol;GO:0005634//nucleus,GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,-
11275,0,42,0,19,96,36,0,2,11,0,0,270,KLHL2;kelch-like family member 2,GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0001726//ruffle;GO:0015629//actin cytoskeleton;GO:0005829//cytosol,GO:0016567//protein ubiquitination,GO:0003779//actin binding;GO:0005515//protein binding,-
112752,0,0,0,0,0,0,27,71,9,0,4,0,IFT43;intraflagellar transport 43,GO:0030991//intraciliary transport particle A;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton,GO:0035721//intraciliary retrograde transport;GO:0060271//cilium morphogenesis,-,-
112755,0,0,0,0,0,0,0,0,26,75,25,0,STX1B;syntaxin 1B,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005819//spindle;GO:0005815//microtubule organizing center,GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006836//neurotransmitter transport;GO:0017157//regulation of exocytosis;GO:0010468//regulation of gene expression;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007268//synaptic transmission,GO:0019904//protein domain specific binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0019901//protein kinase binding;GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity,K08486//SNARE interactions in vesicular transport;Synaptic vesicle cycle
11276,26,0,0,22,86,15,49,0,54,0,6,0,"SYNRG;synergin, gamma",GO:0005794//Golgi apparatus;GO:0030121//AP-1 adaptor complex;GO:0005737//cytoplasm,GO:0006886//intracellular protein transport;GO:0006897//endocytosis,GO:0005509//calcium ion binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
11277,0,23,48,4,0,0,0,0,3,0,0,0,TREX1;three prime repair exonuclease 1,GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006259//DNA metabolic process;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0008219//cell death;GO:0006298//mismatch repair;GO:0035458//cellular response to interferon-beta;GO:0006260//DNA replication;GO:0000738//DNA catabolic process, exonucleolytic",GO:0003697//single-stranded DNA binding;GO:0008296//3'-5'-exodeoxyribonuclease activity;GO:0032407//MutSalpha complex binding;GO:0008408//3'-5' exonuclease activity;GO:0042803//protein homodimerization activity;GO:0032405//MutLalpha complex binding;GO:0008853//exodeoxyribonuclease III activity;GO:0046872//metal ion binding;GO:0032558//adenyl deoxyribonucleotide binding;GO:0003690//double-stranded DNA binding,K10790//Cytosolic DNA-sensing pathway
112770,0,127,1,29,75,35,0,158,0,0,77,0,C1orf85;chromosome 1 open reading frame 85,GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005829//cytosol,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030522//intracellular receptor signaling pathway,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0044212//transcription regulatory region DNA binding,-
11278,0,0,0,0,1,31,40,0,104,94,7,0,KLF12;Kruppel-like factor 12,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003714//transcription corepressor activity;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
11279,0,0,0,0,0,0,8,0,27,0,0,0,KLF8;Kruppel-like factor 8,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1128,0,0,0,10,28,31,0,0,1,0,94,0,"CHRM1;cholinergic receptor, muscarinic 1",GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043679//axon terminus;GO:0032279//asymmetric synapse;GO:0005887//integral component of plasma membrane,GO:0050890//cognition;GO:0090316//positive regulation of intracellular protein transport;GO:0046541//saliva secretion;GO:0043270//positive regulation of ion transport;GO:0008283//cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0007399//nervous system development;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007274//neuromuscular synaptic transmission;GO:0008284//positive regulation of cell proliferation;GO:0006464//cellular protein modification process;GO:0007165//signal transduction;GO:0040012//regulation of locomotion;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0016907//G-protein coupled acetylcholine receptor activity;GO:0008144//drug binding,K04129//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Regulation of actin cytoskeleton;Cholinergic synapse
11280,135,0,0,0,0,32,20,59,83,0,0,0,"SCN11A;sodium channel, voltage-gated, type XI, alpha subunit",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0001518//voltage-gated sodium channel complex;GO:0044299//C-fiber,GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0042493//response to drug;GO:0008219//cell death;GO:0051930//regulation of sensory perception of pain;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0019228//neuronal action potential,GO:0005248//voltage-gated sodium channel activity,-
112802,0,0,0,0,0,10,0,0,27,0,0,0,KRT71;keratin 71,GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament,GO:0031069//hair follicle morphogenesis,GO:0005198//structural molecule activity,-
11281,0,0,0,0,0,0,0,0,23,0,0,249,POU6F2;POU class 6 homeobox 2,GO:0005634//nucleus,"GO:0007402//ganglion mother cell fate determination;GO:0007601//visual perception;GO:0007417//central nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
112812,0,0,0,5,1,0,0,0,1,0,0,0,FDX1L;ferredoxin 1-like,GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0009055//electron carrier activity;GO:0046872//metal ion binding",-
112817,4,0,0,0,15,0,0,0,18,0,24,0,HOGA1;4-hydroxy-2-oxoglutarate aldolase 1,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0033609//oxalate metabolic process;GO:0046487//glyoxylate metabolic process;GO:0042866//pyruvate biosynthetic process;GO:0019470//4-hydroxyproline catabolic process;GO:0009436//glyoxylate catabolic process,GO:0042803//protein homodimerization activity;GO:0008700//4-hydroxy-2-oxoglutarate aldolase activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01639//Amino sugar and nucleotide sugar metabolism;K11447//Transcriptional misregulation in cancer
11282,0,83,30,52,50,1,34,0,26,0,76,0,"MGAT4B;mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006491//N-glycan processing;GO:0043687//post-translational protein modification,"GO:0046872//metal ion binding;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",K00738//Metabolic pathways;N-Glycan biosynthesis
11283,0,0,0,0,0,0,0,0,18,0,0,0,"CYP4F8;cytochrome P450, family 4, subfamily F, polypeptide 8",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006693//prostaglandin metabolic process;GO:0055114//oxidation-reduction process,GO:0018685//alkane 1-monooxygenase activity;GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0020037//heme binding,K00490//Arachidonic acid metabolism;Metabolic pathways
11284,0,0,0,0,0,0,0,0,1,0,10,0,PNKP;polynucleotide kinase 3'-phosphatase,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0016311//dephosphorylation;GO:0009314//response to radiation;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006979//response to oxidative stress;GO:0006261//DNA-dependent DNA replication;GO:0042769//DNA damage response, detection of DNA damage;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0046939//nucleotide phosphorylation;GO:0098506//polynucleotide 3' dephosphorylation",GO:0019201//nucleotide kinase activity;GO:0017076//purine nucleotide binding;GO:0005524//ATP binding;GO:0046404//ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0046403//polynucleotide 3'-phosphatase activity;GO:0005515//protein binding;GO:0004519//endonuclease activity;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding,-
112840,5,0,0,0,3,7,74,0,32,0,0,0,WDR89;WD repeat domain 89,-,-,-,K02084//p53 signaling pathway;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;Apoptosis;Small cell lung cancer;Legionellosis;Tuberculosis;Huntington's disease;Parkinson's disease;K14005//Protein processing in endoplasmic reticulum;K14305//RNA transport
112849,0,0,0,0,0,0,0,0,11,0,4,0,L3HYPDH;L-3-hydroxyproline dehydratase (trans-),-,GO:0008152//metabolic process,GO:0018112//proline racemase activity;GO:0050346//trans-L-3-hydroxyproline dehydratase activity,-
11285,0,0,0,0,0,0,0,29,7,0,0,0,"B4GALT7;xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7",GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane,GO:0030204//chondroitin sulfate metabolic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0006487//protein N-linked glycosylation;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0043206//extracellular fibril organization;GO:0006029//proteoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process,"GO:0008378//galactosyltransferase activity;GO:0046525//xylosylprotein 4-beta-galactosyltransferase activity;GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0030145//manganese ion binding",K00733//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
112858,0,0,1,27,51,0,16,0,14,0,0,0,TP53RK;TP53 regulating kinase,GO:0016020//membrane;GO:0005634//nucleus,GO:0008033//tRNA processing;GO:0006468//protein phosphorylation;GO:0009103//lipopolysaccharide biosynthetic process,GO:0004674//protein serine/threonine kinase activity;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0005524//ATP binding,-
112869,16,18,0,0,0,0,0,40,5,237,46,0,CCDC101;coiled-coil domain containing 101,GO:0070461//SAGA-type complex;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,"GO:0071169//establishment of protein localization to chromatin;GO:0006351//transcription, DNA-templated;GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated",GO:0035064//methylated histone binding;GO:0005515//protein binding,-
112885,36,0,17,0,0,0,0,0,60,0,0,0,PHF21B;PHD finger protein 21B,-,-,GO:0008270//zinc ion binding,-
1129,0,0,0,0,0,0,0,0,32,0,0,0,"CHRM2;cholinergic receptor, muscarinic 2",GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0005887//integral component of plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0008016//regulation of heart contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0009615//response to virus;GO:0007399//nervous system development;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway",GO:0016907//G-protein coupled acetylcholine receptor activity,K04130//Regulation of actin cytoskeleton;Cholinergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction
112936,2,2603,1459,1747,3024,0,497,5729,1011,190,7276,3,VPS26B;vacuolar protein sorting 26 homolog B (S. pombe),GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane,GO:0015031//protein transport,-,-
112937,28,1,2,31,67,11,35,417,0,19,168,1,"GLB1L3;galactosidase, beta 1-like 3",-,GO:0005975//carbohydrate metabolic process,GO:0004565//beta-galactosidase activity,K12309//Lysosome;Sphingolipid metabolism;Metabolic pathways;Galactose metabolism;Glycosphingolipid biosynthesis - ganglio series;Glycosaminoglycan degradation;Other glycan degradation
112939,0,13,0,2,10,0,0,145,19,0,0,1,"NACC1;nucleus accumbens associated 1, BEN and BTB (POZ) domain containing",GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016604//nuclear body,"GO:0008284//positive regulation of cell proliferation;GO:0051260//protein homooligomerization;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",-,-
112942,0,1,27,17,7,0,0,48,52,0,18,0,CCDC104;coiled-coil domain containing 104,-,-,-,-
112950,0,56,142,41,37,0,0,0,26,0,12,304,MED8;mediator complex subunit 8,GO:0005654//nucleoplasm;GO:0016592//mediator complex,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0016567//protein ubiquitination,GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity,K15129//Herpes simplex infection
113,0,38,0,42,17,14,0,85,59,0,97,1,ADCY7;adenylate cyclase 7,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0006171//cAMP biosynthetic process;GO:0045087//innate immune response;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007202//activation of phospholipase C activity;GO:0071361//cellular response to ethanol;GO:0055085//transmembrane transport;GO:0035556//intracellular signal transduction;GO:0034199//activation of protein kinase A activity;GO:0006833//water transport;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0060135//maternal process involved in female pregnancy;GO:0006112//energy reserve metabolic process,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity,K08047//Purine metabolism;Vascular smooth muscle contraction;Oocyte meiosis;Morphine addiction;Glutamatergic synapse;Progesterone-mediated oocyte maturation;Pancreatic secretion;GnRH signaling pathway;Chemokine signaling pathway;Gap junction;Bile secretion;Melanogenesis;Gastric acid secretion;Salivary secretion;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Calcium signaling pathway;Cholinergic synapse;HTLV-I infection;GABAergic synapse
1130,0,0,0,1,0,0,0,0,11,0,6,0,LYST;lysosomal trafficking regulator,GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton,GO:0006644//phospholipid metabolic process;GO:0033299//secretion of lysosomal enzymes;GO:0051607//defense response to virus;GO:0002446//neutrophil mediated immunity;GO:0055091//phospholipid homeostasis;GO:0032816//positive regulation of natural killer cell activation;GO:0007596//blood coagulation;GO:0033364//mast cell secretory granule organization;GO:0030595//leukocyte chemotaxis;GO:0032438//melanosome organization;GO:0007017//microtubule-based process;GO:0042493//response to drug;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0043473//pigmentation;GO:0002456//T cell mediated immunity;GO:0042267//natural killer cell mediated cytotoxicity;GO:0042832//defense response to protozoan;GO:0007040//lysosome organization;GO:0042742//defense response to bacterium,GO:0005515//protein binding,K10599//Ubiquitin mediated proteolysis;Spliceosome;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
113000,0,0,0,0,0,0,0,0,37,0,16,0,RPUSD1;RNA pseudouridylate synthase domain containing 1,-,GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0003723//RNA binding,K01718//Pyrimidine metabolism
113026,0,0,0,0,17,1,0,1,19,1,0,650,"PLCD3;phospholipase C, delta 3",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0032154//cleavage furrow,GO:0042127//regulation of cell proliferation;GO:0060716//labyrinthine layer blood vessel development;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0001525//angiogenesis;GO:0035556//intracellular signal transduction,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004871//signal transducer activity;GO:0005509//calcium ion binding,K05857//Inositol phosphate metabolism;Calcium signaling pathway;Metabolic pathways;Phosphatidylinositol signaling system
11309,0,0,0,0,0,1,20,1,13,0,9,0,"SLCO2B1;solute carrier organic anion transporter family, member 2B1",GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0001889//liver development;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport;GO:0043252//sodium-independent organic anion transport;GO:0071718//sodium-independent icosanoid transport,GO:0015125//bile acid transmembrane transporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity,-
1131,0,0,0,0,0,0,0,59,18,0,0,1,"CHRM3;cholinergic receptor, muscarinic 3",GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043679//axon terminus;GO:0032279//asymmetric synapse;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007399//nervous system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0046541//saliva secretion;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0006464//cellular protein modification process;GO:0003056//regulation of vascular smooth muscle contraction;GO:0006939//smooth muscle contraction;GO:0045987//positive regulation of smooth muscle contraction,GO:0005515//protein binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0042166//acetylcholine binding;GO:0016907//G-protein coupled acetylcholine receptor activity;GO:0008144//drug binding;GO:0004872//receptor activity,K04131//Cholinergic synapse;Regulation of actin cytoskeleton;Pancreatic secretion;Gastric acid secretion;Calcium signaling pathway;Salivary secretion;Neuroactive ligand-receptor interaction
11311,0,28,0,28,46,6,0,0,17,88,16,0,VPS45;vacuolar protein sorting 45 homolog (S. cerevisiae),GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006904//vesicle docking involved in exocytosis;GO:0007596//blood coagulation;GO:0006886//intracellular protein transport,-,K12479//Endocytosis
113115,0,0,0,0,5,0,17,0,11,0,0,0,MTFR2;mitochondrial fission regulator 2,GO:0005739//mitochondrion,GO:0009060//aerobic respiration;GO:0007005//mitochondrion organization;GO:0000266//mitochondrial fission,-,-
11313,0,0,0,0,1,14,0,19,9,0,0,0,LYPLA2;lysophospholipase II,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006631//fatty acid metabolic process,GO:0016787//hydrolase activity,K06130//Glycerophospholipid metabolism
113130,87,3,0,0,0,13,0,22,0,0,6,1,CDCA5;cell division cycle associated 5,"GO:0005886//plasma membrane;GO:0005694//chromosome;GO:0008278//cohesin complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0000790//nuclear chromatin;GO:0005634//nucleus",GO:0000082//G1/S transition of mitotic cell cycle;GO:0007076//mitotic chromosome condensation;GO:0007067//mitotic nuclear division;GO:0006302//double-strand break repair;GO:0071922//regulation of cohesin localization to chromatin;GO:0007064//mitotic sister chromatid cohesion;GO:0007080//mitotic metaphase plate congression;GO:0000278//mitotic cell cycle,GO:0003682//chromatin binding;GO:0005515//protein binding,-
11314,65,0,0,0,0,2,0,0,34,0,6,0,CD300A;CD300a molecule,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0048147//negative regulation of fibroblast proliferation;GO:0007155//cell adhesion;GO:0050856//regulation of T cell receptor signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0002376//immune system process;GO:0007165//signal transduction;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0030889//negative regulation of B cell proliferation;GO:0051134//negative regulation of NK T cell activation;GO:1902569//negative regulation of activation of JAK2 kinase activity;GO:0043305//negative regulation of mast cell degranulation;GO:0060101//negative regulation of phagocytosis, engulfment;GO:1902567//negative regulation of eosinophil activation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:2000417//negative regulation of eosinophil migration;GO:1902564//negative regulation of neutrophil activation",GO:0005515//protein binding;GO:0038023//signaling receptor activity;GO:0001786//phosphatidylserine binding;GO:0008429//phosphatidylethanolamine binding,-
113146,66,0,0,7,11,27,43,33,75,0,27,211,AHNAK2;AHNAK nucleoprotein 2,GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane;GO:0043034//costamere;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0042383//sarcolemma,GO:0001778//plasma membrane repair,GO:0005515//protein binding,K14398//mRNA surveillance pathway;K13911//Salivary secretion
11315,0,155,1,172,412,0,18,0,0,0,0,0,PARK7;parkinson protein 7,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045121//membrane raft;GO:0005634//nucleus;GO:0000785//chromatin;GO:0005747//mitochondrial respiratory chain complex I;GO:0016605//PML body;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0045560//regulation of TRAIL receptor biosynthetic process;GO:0001933//negative regulation of protein phosphorylation;GO:1901215//negative regulation of neuron death;GO:1900182//positive regulation of protein localization to nucleus;GO:0032091//negative regulation of protein binding;GO:1903094//negative regulation of protein K48-linked deubiquitination;GO:0043066//negative regulation of apoptotic process;GO:2000825//positive regulation of androgen receptor activity;GO:0060081//membrane hyperpolarization;GO:0010629//negative regulation of gene expression;GO:2000157//negative regulation of ubiquitin-specific protease activity;GO:0042743//hydrogen peroxide metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0051881//regulation of mitochondrial membrane potential;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0006914//autophagy;GO:0060548//negative regulation of cell death;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0032757//positive regulation of interleukin-8 production;GO:0046826//negative regulation of protein export from nucleus;GO:0043524//negative regulation of neuron apoptotic process;GO:0008344//adult locomotory behavior;GO:0051899//membrane depolarization;GO:0034599//cellular response to oxidative stress;GO:0007005//mitochondrion organization;GO:0060765//regulation of androgen receptor signaling pathway;GO:0007338//single fertilization;GO:0043523//regulation of neuron apoptotic process;GO:0070301//cellular response to hydrogen peroxide;GO:0050727//regulation of inflammatory response;GO:0019249//lactate biosynthetic process;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0050821//protein stabilization;GO:1903073//negative regulation of death-inducing signaling complex assembly;GO:0006469//negative regulation of protein kinase activity;GO:0090073//positive regulation of protein homodimerization activity;GO:0033234//negative regulation of protein sumoylation;GO:0055114//oxidation-reduction process;GO:1901984//negative regulation of protein acetylation;GO:0031397//negative regulation of protein ubiquitination;GO:0006508//proteolysis;GO:0006954//inflammatory response;GO:2000277//positive regulation of oxidative phosphorylation uncoupler activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0019955//cytokine binding;GO:0019899//enzyme binding;GO:0001047//core promoter binding;GO:0051920//peroxiredoxin activity;GO:0042802//identical protein binding;GO:0044390//small protein conjugating enzyme binding;GO:0070491//repressing transcription factor binding;GO:0003729//mRNA binding;GO:0016532//superoxide dismutase copper chaperone activity;GO:1990381//ubiquitin-specific protease binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008233//peptidase activity;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0003697//single-stranded DNA binding;GO:0005102//receptor binding;GO:0097110//scaffold protein binding;GO:0003690//double-stranded DNA binding;GO:0044388//small protein activating enzyme binding;GO:0004601//peroxidase activity;GO:0042803//protein homodimerization activity,K05687//Parkinson's disease
113157,99,61,48,11,21,0,0,5,15,282,187,0,"RPLP0P2;ribosomal protein, large, P0 pseudogene 2",-,-,-,K02941//Ribosome
11316,0,0,0,1,2,0,0,12,17,0,0,0,"COPE;coatomer protein complex, subunit epsilon",GO:0030126//COPI vesicle coat;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,"GO:0048205//COPI coating of Golgi vesicle;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0015031//protein transport",GO:0005198//structural molecule activity,-
11317,0,0,0,0,0,22,57,9,43,0,0,0,RBPJL;recombination signal binding protein for immunoglobulin kappa J region-like,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K06053//Epstein-Barr virus infection;Notch signaling pathway
113174,0,52,0,0,0,9,0,0,0,257,0,0,SAAL1;serum amyloid A-like 1,-,-,-,-
113177,0,0,0,0,0,20,0,0,0,0,6,0,IZUMO4;IZUMO family member 4,GO:0005576//extracellular region;GO:0005634//nucleus,-,-,-
113178,0,3,1,0,12,9,18,0,1,0,0,0,SCAMP4;secretory carrier membrane protein 4,GO:0016021//integral component of membrane,GO:0015031//protein transport,-,K08823//Legionellosis;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
113179,0,0,0,0,0,0,19,0,0,125,1,0,"ADAT3;adenosine deaminase, tRNA-specific 3",-,GO:0008033//tRNA processing,GO:0008270//zinc ion binding;GO:0016787//hydrolase activity,-
11318,0,0,0,0,0,0,0,0,14,0,4,0,GPR182;G protein-coupled receptor 182,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004888//transmembrane signaling receptor activity,-
113189,0,0,0,0,0,32,0,0,38,0,0,62,CHST14;carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0030204//chondroitin sulfate metabolic process;GO:0044281//small molecule metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0005975//carbohydrate metabolic process,GO:0042301//phosphate ion binding;GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity,K08105//Glycosaminoglycan biosynthesis - chondroitin sulfate
11319,0,0,0,17,32,0,0,7,25,70,0,934,ECD;ecdysoneless homolog (Drosophila),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006110//regulation of glycolytic process;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003713//transcription coactivator activity,-
1132,0,0,0,0,0,0,12,0,18,0,0,0,"CHRM4;cholinergic receptor, muscarinic 4",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0007197//adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0040012//regulation of locomotion;GO:0007165//signal transduction,GO:0016907//G-protein coupled acetylcholine receptor activity,K04132//Cholinergic synapse;Regulation of actin cytoskeleton;Neuroactive ligand-receptor interaction
11320,71,0,0,0,31,19,18,0,56,0,0,0,"MGAT4A;mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A",GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0006491//N-glycan processing;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,"GO:0046872//metal ion binding;GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",K00738//N-Glycan biosynthesis;Metabolic pathways
113201,0,4,80,48,147,24,0,0,9,0,0,0,CASC4;cancer susceptibility candidate 4,GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
11321,141,36,49,68,56,33,0,0,0,0,11,1,GPN1;GPN-loop GTPase 1,GO:0005737//cytoplasm,-,GO:0005525//GTP binding,-
11322,0,0,0,0,0,12,0,25,28,0,0,0,TMC6;transmembrane channel-like 6,GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0006811//ion transport,GO:0005515//protein binding,-
113220,0,0,6,0,0,0,0,0,7,0,0,0,KIF12;kinesin family member 12,GO:0070062//extracellular vesicular exosome;GO:0005871//kinesin complex;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding,-
113230,1,0,0,0,23,0,0,0,1,0,0,0,LOC113230;uncharacterized protein LOC113230,-,-,-,-
113235,69,1047,489,727,978,5,55,826,211,0,1483,1,"SLC46A1;solute carrier family 46 (folate transporter), member 1",GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0051958//methotrexate transport;GO:0015886//heme transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0046655//folic acid metabolic process;GO:0015884//folic acid transport;GO:0006879//cellular iron ion homeostasis;GO:0006766//vitamin metabolic process;GO:0055085//transmembrane transport,GO:0005542//folic acid binding;GO:0015350//methotrexate transporter activity;GO:0015232//heme transporter activity;GO:0008517//folic acid transporter activity,K14613//Vitamin digestion and absorption;Mineral absorption
11325,97,0,0,8,177,0,0,4,26,133,8,0,DDX42;DEAD (Asp-Glu-Ala-Asp) box helicase 42,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015030//Cajal body,GO:0008104//protein localization;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity,K12835//Spliceosome
113251,0,1,1,76,345,28,48,0,38,0,1,0,"LARP4;La ribonucleoprotein domain family, member 4",GO:0016020//membrane,GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization,GO:0044822//poly(A) RNA binding,K11090//Systemic lupus erythematosus
11326,0,0,0,0,0,0,0,0,31,0,0,0,VSIG4;V-set and immunoglobulin domain containing 4,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,"GO:0042130//negative regulation of T cell proliferation;GO:0032703//negative regulation of interleukin-2 production;GO:0006957//complement activation, alternative pathway",GO:0005515//protein binding,K06089//Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Epithelial cell signaling in Helicobacter pylori infection
113263,0,0,25,0,19,0,0,47,0,0,0,0,GLCCI1;glucocorticoid induced transcript 1,GO:0005737//cytoplasm,-,-,-
113277,0,0,0,0,0,0,0,0,25,0,0,0,TMEM106A;transmembrane protein 106A,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
113278,0,0,0,0,1,0,14,0,26,0,0,195,"SLC52A3;solute carrier family 52 (riboflavin transporter), member 3",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006771//riboflavin metabolic process;GO:0034605//cellular response to heat;GO:0032218//riboflavin transport;GO:0006766//vitamin metabolic process;GO:0007605//sensory perception of sound,GO:0032217//riboflavin transporter activity,K14620//Vitamin digestion and absorption
11328,0,0,15,0,4,3,0,36,69,158,14,1,"FKBP9;FK506 binding protein 9, 63 kDa",GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding,GO:0005528//FK506 binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding,-
11329,27,20,0,0,6,31,15,0,34,0,2,0,STK38;serine/threonine kinase 38,GO:0070688//MLL5-L complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043407//negative regulation of MAP kinase activity;GO:0006464//cellular protein modification process;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005524//ATP binding,-
1133,0,0,0,0,0,13,0,0,29,0,12,0,"CHRM5;cholinergic receptor, muscarinic 5",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0019226//transmission of nerve impulse;GO:0060304//regulation of phosphatidylinositol dephosphorylation;GO:0008283//cell proliferation;GO:0008152//metabolic process;GO:0001696//gastric acid secretion;GO:0007197//adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway;GO:0015872//dopamine transport;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0016907//G-protein coupled acetylcholine receptor activity,K04133//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Cholinergic synapse;Regulation of actin cytoskeleton
11330,0,0,0,0,0,0,19,0,0,0,0,0,CTRC;chymotrypsin C (caldecrin),-,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity,-
11331,0,26,0,6,42,13,0,2,0,0,0,0,PHB2;prohibitin 2,GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0043234//protein complex,"GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0060744//mammary gland branching involved in thelarche;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060749//mammary gland alveolus development;GO:0006351//transcription, DNA-templated",GO:0030331//estrogen receptor binding;GO:0005515//protein binding,-
11332,77,0,0,0,0,0,0,0,15,0,0,0,ACOT7;acyl-CoA thioesterase 7,GO:0005737//cytoplasm;GO:0044297//cell body;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0036116//long-chain fatty-acyl-CoA catabolic process;GO:0009062//fatty acid catabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0051792//medium-chain fatty acid biosynthetic process;GO:0036114//medium-chain fatty-acyl-CoA catabolic process;GO:1900535//palmitic acid biosynthetic process,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0000062//fatty-acyl-CoA binding;GO:0036042//long-chain fatty acyl-CoA binding;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity,K01068//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
11333,0,176,129,206,272,0,0,146,41,0,166,0,PDAP1;PDGFA associated protein 1,-,GO:0008283//cell proliferation;GO:0007165//signal transduction,GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
11334,0,0,1,15,6,0,0,0,33,0,0,0,TUSC2;tumor suppressor candidate 2,GO:0005739//mitochondrion,GO:0007049//cell cycle;GO:0007267//cell-cell signaling;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0048469//cell maturation;GO:0006954//inflammatory response;GO:0001779//natural killer cell differentiation;GO:0006909//phagocytosis;GO:0071609//chemokine (C-C motif) ligand 5 production;GO:0032618//interleukin-15 production;GO:0032700//negative regulation of interleukin-17 production;GO:0032733//positive regulation of interleukin-10 production;GO:0051881//regulation of mitochondrial membrane potential;GO:0008283//cell proliferation,-,-
11335,0,67,0,31,77,6,0,61,26,0,8,0,CBX3;chromobox homolog 3,"GO:0031618//nuclear pericentric heterochromatin;GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0000785//chromatin;GO:0005637//nuclear inner membrane;GO:0005719//nuclear euchromatin;GO:0005819//spindle;GO:0005720//nuclear heterochromatin;GO:0000779//condensed chromosome, centromeric region","GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process",GO:1990226//histone methyltransferase binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0042802//identical protein binding,-
11336,0,0,0,21,34,0,2,0,49,0,0,1,EXOC3;exocyst complex component 3,GO:0000145//exocyst;GO:0030667//secretory granule membrane,GO:0061024//membrane organization;GO:0015031//protein transport;GO:0044267//cellular protein metabolic process;GO:0006887//exocytosis,GO:0005515//protein binding,K06110//Tight junction
11337,0,169,23,63,312,0,1,0,3,318,0,1,GABARAP;GABA(A) receptor-associated protein,GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0044297//cell body;GO:0015629//actin cytoskeleton;GO:0005875//microtubule associated complex;GO:0005764//lysosome;GO:0005874//microtubule;GO:0005790//smooth endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0000421//autophagic vacuole membrane;GO:0005930//axoneme;GO:0005776//autophagic vacuole,GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0007268//synaptic transmission;GO:0000226//microtubule cytoskeleton organization;GO:0006605//protein targeting;GO:0006914//autophagy,GO:0050811//GABA receptor binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0048487//beta-tubulin binding,K08341//GABAergic synapse;Regulation of autophagy
11338,0,10,0,5,81,0,10,0,28,0,59,0,U2AF2;U2 small nuclear RNA auxiliary factor 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0016607//nuclear speck,"GO:0031124//mRNA 3'-end processing;GO:0006406//mRNA export from nucleus;GO:0006369//termination of RNA polymerase II transcription;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome",GO:0019899//enzyme binding;GO:0070742//C2H2 zinc finger domain binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12837//Spliceosome
11339,0,0,29,0,16,5,0,0,32,0,5,0,OIP5;Opa interacting protein 5,"GO:0010369//chromocenter;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region",GO:0006334//nucleosome assembly;GO:0007154//cell communication;GO:0034080//CENP-A containing nucleosome assembly;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
1134,0,0,0,0,0,0,10,0,0,8,6,0,"CHRNA1;cholinergic receptor, nicotinic, alpha 1 (muscle)",GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0007528//neuromuscular junction development;GO:0048630//skeletal muscle tissue growth;GO:0007274//neuromuscular synaptic transmission;GO:0007268//synaptic transmission;GO:0019228//neuronal action potential;GO:0042391//regulation of membrane potential;GO:0003009//skeletal muscle contraction;GO:0006812//cation transport;GO:0050905//neuromuscular process;GO:0046716//muscle cell cellular homeostasis;GO:0070050//neuron cellular homeostasis;GO:0034220//ion transmembrane transport;GO:0050881//musculoskeletal movement;GO:0006810//transport,GO:0015464//acetylcholine receptor activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0005216//ion channel activity;GO:0042166//acetylcholine binding,K04803//Neuroactive ligand-receptor interaction
11340,0,0,0,0,8,0,0,0,0,0,10,0,EXOSC8;exosome component 8,GO:0005634//nucleus;GO:0000178//exosome (RNase complex);GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006364//rRNA processing;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression",GO:0004532//exoribonuclease activity;GO:0017091//AU-rich element binding;GO:0005515//protein binding,K12586//RNA degradation
113402,0,1,0,0,0,16,0,0,0,0,0,0,SFT2D1;SFT2 domain containing 1,GO:0016021//integral component of membrane,GO:0016192//vesicle-mediated transport;GO:0015031//protein transport,-,-
11341,65,0,0,0,17,0,23,0,0,0,7,2,SCRG1;stimulator of chondrogenesis 1,GO:0005615//extracellular space,GO:0007399//nervous system development,-,-
113419,1,0,0,1,10,0,26,1,0,0,9,0,TEX261;testis expressed 261,GO:0016021//integral component of membrane,-,-,-
11342,0,0,0,33,135,0,0,0,13,0,0,0,RNF13;ring finger protein 13,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005637//nuclear inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane,GO:0051865//protein autoubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
11343,0,0,1,2,0,0,23,62,20,0,6,0,MGLL;monoglyceride lipase,GO:0005886//plasma membrane;GO:0045202//synapse;GO:0005789//endoplasmic reticulum membrane,GO:0060292//long term synaptic depression;GO:0019369//arachidonic acid metabolic process;GO:0007596//blood coagulation;GO:0009966//regulation of signal transduction;GO:0036155//acylglycerol acyl-chain remodeling;GO:0051930//regulation of sensory perception of pain;GO:0030168//platelet activation;GO:0006633//fatty acid biosynthetic process;GO:0006954//inflammatory response;GO:0006644//phospholipid metabolic process;GO:0019433//triglyceride catabolic process;GO:0050727//regulation of inflammatory response;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:2000124//regulation of endocannabinoid signaling pathway,GO:0042803//protein homodimerization activity;GO:0047372//acylglycerol lipase activity;GO:0004622//lysophospholipase activity;GO:0008289//lipid binding,K01054//Retrograde endocannabinoid signaling;Glycerolipid metabolism;Metabolic pathways
11344,0,0,0,0,3,0,31,56,52,0,17,0,TWF2;twinfilin actin-binding protein 2,GO:0030016//myofibril;GO:0070062//extracellular vesicular exosome;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005856//cytoskeleton;GO:0032420//stereocilium;GO:0048471//perinuclear region of cytoplasm,GO:0030030//cell projection organization;GO:0030837//negative regulation of actin filament polymerization;GO:0010976//positive regulation of neuron projection development;GO:0042989//sequestering of actin monomers;GO:0071300//cellular response to retinoic acid;GO:0051016//barbed-end actin filament capping;GO:0071363//cellular response to growth factor stimulus;GO:0045773//positive regulation of axon extension;GO:0010592//positive regulation of lamellipodium assembly;GO:0032956//regulation of actin cytoskeleton organization;GO:0032532//regulation of microvillus length,"GO:0003785//actin monomer binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005080//protein kinase C binding",-
113444,0,7,79,10,17,0,0,57,51,19,31,0,SMIM12;small integral membrane protein 12,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
11345,0,41,3,26,43,0,0,0,0,0,0,0,GABARAPL2;GABA(A) receptor-associated protein-like 2,GO:0000421//autophagic vacuole membrane;GO:0005776//autophagic vacuole;GO:0005829//cytosol;GO:0005622//intracellular;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,GO:0032781//positive regulation of ATPase activity;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0006914//autophagy;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0000149//SNARE binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0051117//ATPase binding;GO:0050811//GABA receptor binding,K08341//Regulation of autophagy;GABAergic synapse
113451,0,0,0,0,0,3,25,0,0,0,3,0,AZIN2;antizyme inhibitor 2,GO:0043204//perikaryon;GO:0030424//axon;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0030425//dendrite;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005801//cis-Golgi network;GO:0030133//transport vesicle;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle,GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0097055//agmatine biosynthetic process;GO:0042177//negative regulation of protein catabolic process;GO:0006591//ornithine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0007283//spermatogenesis;GO:0043085//positive regulation of catalytic activity;GO:0006596//polyamine biosynthetic process,GO:0005515//protein binding;GO:0016831//carboxy-lyase activity;GO:0042978//ornithine decarboxylase activator activity,K01583//Arginine and proline metabolism;Metabolic pathways
113452,0,0,0,12,0,0,0,1,0,0,1,0,TMEM54;transmembrane protein 54,GO:0016021//integral component of membrane,-,-,-
113457,0,0,0,36,7,12,0,1,23,0,22,1,"TUBA3D;tubulin, alpha 3d",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005874//microtubule,GO:0007017//microtubule-based process;GO:0044267//cellular protein metabolic process;GO:0051258//protein polymerization;GO:0051084//'de novo' posttranslational protein folding;GO:0006184//GTP catabolic process;GO:0006457//protein folding,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,K07374//Pathogenic Escherichia coli infection;Gap junction;Phagosome
11346,124,0,0,0,0,61,35,0,27,201,17,0,SYNPO;synaptopodin,GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0001725//stress fiber;GO:0015629//actin cytoskeleton;GO:0043204//perikaryon;GO:0005923//tight junction,GO:0032233//positive regulation of actin filament bundle assembly;GO:0051492//regulation of stress fiber assembly,GO:0003779//actin binding;GO:0005515//protein binding,K06237//ECM-receptor interaction;Pathways in cancer;Focal adhesion;Protein digestion and absorption;Small cell lung cancer;Amoebiasis
1135,85,0,0,0,3,40,18,0,8,3,0,179,"CHRNA2;cholinergic receptor, nicotinic, alpha 2 (neuronal)",GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0006812//cation transport;GO:0051291//protein heterooligomerization;GO:0007165//signal transduction;GO:0007268//synaptic transmission,GO:0042166//acetylcholine binding;GO:0015464//acetylcholine receptor activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0008144//drug binding,K04804//Neuroactive ligand-receptor interaction
113540,0,0,0,0,0,0,0,0,2,0,0,178,CMTM1;CKLF-like MARVEL transmembrane domain containing 1,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
1136,0,0,0,1,0,22,0,0,14,0,0,0,"CHRNA3;cholinergic receptor, nicotinic, alpha 3 (neuronal)",GO:0030054//cell junction;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0005892//acetylcholine-gated channel complex;GO:0043025//neuronal cell body;GO:0014069//postsynaptic density,"GO:0007271//synaptic transmission, cholinergic;GO:0035095//behavioral response to nicotine;GO:0006940//regulation of smooth muscle contraction;GO:0007626//locomotory behavior;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0042391//regulation of membrane potential;GO:0014056//regulation of acetylcholine secretion, neurotransmission;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0006811//ion transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0048814//regulation of dendrite morphogenesis;GO:0034220//ion transmembrane transport;GO:0060084//synaptic transmission involved in micturition",GO:0015276//ligand-gated ion channel activity;GO:0015464//acetylcholine receptor activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0042166//acetylcholine binding,K04805//Neuroactive ligand-receptor interaction;Cholinergic synapse
113612,0,0,0,5,26,35,1,0,35,36,0,0,"CYP2U1;cytochrome P450, family 2, subfamily U, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0019369//arachidonic acid metabolic process;GO:0008219//cell death;GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0097267//omega-hydroxylase P450 pathway;GO:0044281//small molecule metabolic process,GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0020037//heme binding,K07422//Arachidonic acid metabolism;Metabolic pathways
113622,0,0,0,0,1,0,0,4,44,0,6,0,ADPRHL1;ADP-ribosylhydrolase like 1,-,GO:0051725//protein de-ADP-ribosylation,GO:0003875//ADP-ribosylarginine hydrolase activity;GO:0000287//magnesium ion binding,-
113655,0,0,0,7,16,0,0,0,1,24,0,0,MFSD3;major facilitator superfamily domain containing 3,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
113675,0,0,0,0,0,18,0,0,18,0,5,0,SDSL;serine dehydratase-like,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0006520//cellular amino acid metabolic process,GO:0003941//L-serine ammonia-lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0004794//L-threonine ammonia-lyase activity,"K01752//Biosynthesis of secondary metabolites;Cysteine and methionine metabolism;Glycine, serine and threonine metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis"
113691,0,56,1,0,0,0,0,104,0,0,3,0,"TUBA3FP;tubulin, alpha 3f, pseudogene",-,-,-,K07374//Pathogenic Escherichia coli infection;Gap junction;Phagosome
1137,0,0,0,0,0,11,0,101,39,22,2,1,"CHRNA4;cholinergic receptor, nicotinic, alpha 4 (neuronal)",GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005892//acetylcholine-gated channel complex;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0009897//external side of plasma membrane;GO:0030054//cell junction;GO:0043025//neuronal cell body,"GO:0042113//B cell activation;GO:0035094//response to nicotine;GO:0006281//DNA repair;GO:0007165//signal transduction;GO:0051899//membrane depolarization;GO:0019233//sensory perception of pain;GO:0035640//exploration behavior;GO:0006979//response to oxidative stress;GO:0007268//synaptic transmission;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0050890//cognition;GO:0001666//response to hypoxia;GO:0034220//ion transmembrane transport;GO:0007271//synaptic transmission, cholinergic;GO:0035095//behavioral response to nicotine;GO:0007585//respiratory gaseous exchange;GO:0007626//locomotory behavior;GO:0001508//action potential;GO:0050877//neurological system process;GO:0042391//regulation of membrane potential;GO:0014059//regulation of dopamine secretion;GO:0006816//calcium ion transport;GO:0006811//ion transport",GO:0015276//ligand-gated ion channel activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity;GO:0042166//acetylcholine binding,K04806//Neuroactive ligand-receptor interaction;Cholinergic synapse;Nicotine addiction
113730,0,0,0,0,0,0,0,0,6,0,11,0,KLHDC7B;kelch domain containing 7B,-,-,-,-
113746,0,0,0,0,0,0,0,0,31,0,0,0,ODF3;outer dense fiber of sperm tails 3,GO:0001520//outer dense fiber,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,-
113763,3,0,0,0,0,0,1,50,29,0,0,0,ZBED6CL;ZBED6 C-terminal like,-,-,-,-
113791,0,16,45,31,32,0,2,55,9,0,15,0,PIK3IP1;phosphoinositide-3-kinase interacting protein 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity,GO:0036313//phosphatidylinositol 3-kinase catalytic subunit binding,K01343//Transcriptional misregulation in cancer;Complement and coagulation cascades
1138,70,0,0,0,0,0,17,0,90,0,0,0,"CHRNA5;cholinergic receptor, nicotinic, alpha 5 (neuronal)",GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0035095//behavioral response to nicotine;GO:0007165//signal transduction;GO:0007268//synaptic transmission,GO:0015276//ligand-gated ion channel activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity,K04807//Neuroactive ligand-receptor interaction
113802,0,0,1,0,18,15,1,0,31,0,1,0,HENMT1;HEN1 methyltransferase homolog 1 (Arabidopsis),GO:0043186//P granule,GO:0034587//piRNA metabolic process;GO:0031047//gene silencing by RNA;GO:0001510//RNA methylation,GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0008173//RNA methyltransferase activity;GO:0008171//O-methyltransferase activity,-
113828,0,0,0,1,1,0,0,30,14,0,7,0,"FAM83F;family with sequence similarity 83, member F",-,-,-,-
113829,0,0,0,0,11,0,0,85,11,0,0,0,"SLC35A4;solute carrier family 35, member A4",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0008643//carbohydrate transport;GO:0015992//proton transport,GO:0005351//sugar:proton symporter activity,-
113835,0,0,0,0,1,0,0,0,33,0,0,0,ZNF257;zinc finger protein 257,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
113878,0,0,0,0,0,14,16,0,11,0,0,0,"DTX2;deltex 2, E3 ubiquitin ligase",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005730//nucleolus,GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,K06058//Notch signaling pathway
1139,0,0,0,0,2,0,0,0,17,0,0,0,"CHRNA7;cholinergic receptor, nicotinic, alpha 7 (neuronal)",GO:0030054//cell junction;GO:0043198//dendritic shaft;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0009897//external side of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0014069//postsynaptic density;GO:0030424//axon;GO:0032279//asymmetric synapse,"GO:0042113//B cell activation;GO:0042416//dopamine biosynthetic process;GO:0007165//signal transduction;GO:0032715//negative regulation of interleukin-6 production;GO:0060112//generation of ovulation cycle rhythm;GO:0050728//negative regulation of inflammatory response;GO:0007268//synaptic transmission;GO:0001666//response to hypoxia;GO:0034220//ion transmembrane transport;GO:0035095//behavioral response to nicotine;GO:0006874//cellular calcium ion homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0030317//sperm motility;GO:0032691//negative regulation of interleukin-1 beta production;GO:0000187//activation of MAPK activity;GO:0032094//response to food;GO:0035094//response to nicotine;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0007613//memory;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006897//endocytosis;GO:0050890//cognition;GO:0007271//synaptic transmission, cholinergic;GO:0008284//positive regulation of cell proliferation;GO:0001988//positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure;GO:0019228//neuronal action potential;GO:0014061//regulation of norepinephrine secretion;GO:0008306//associative learning;GO:0006816//calcium ion transport;GO:0042110//T cell activation;GO:0048149//behavioral response to ethanol;GO:0006811//ion transport",GO:0051117//ATPase binding;GO:0019901//protein kinase binding;GO:0017081//chloride channel regulator activity;GO:0015464//acetylcholine receptor activity;GO:0008144//drug binding;GO:0022848//acetylcholine-gated cation channel activity;GO:0015643//toxic substance binding;GO:0042803//protein homodimerization activity;GO:0042166//acetylcholine binding;GO:0008179//adenylate cyclase binding;GO:0097110//scaffold protein binding;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0001540//beta-amyloid binding,K04809//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Cholinergic synapse;Nicotine addiction
114,0,0,0,0,0,0,30,0,32,0,18,243,ADCY8;adenylate cyclase 8 (brain),GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007611//learning or memory;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0007616//long-term memory;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034199//activation of protein kinase A activity;GO:0006833//water transport;GO:0007165//signal transduction;GO:0006112//energy reserve metabolic process;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0008294//calcium- and calmodulin-responsive adenylate cyclase activity;GO:0005524//ATP binding;GO:0004016//adenylate cyclase activity;GO:0046872//metal ion binding,K08048//Purine metabolism;Taste transduction;Glutamatergic synapse;Vascular smooth muscle contraction;Oocyte meiosis;Morphine addiction;Pancreatic secretion;Progesterone-mediated oocyte maturation;Long-term potentiation;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Gastric acid secretion;Melanogenesis;Bile secretion;Retrograde endocannabinoid signaling;Dilated cardiomyopathy;Calcium signaling pathway;Salivary secretion;GABAergic synapse;Cholinergic synapse;HTLV-I infection
1140,0,0,0,6,0,0,16,0,32,5,0,0,"CHRNB1;cholinergic receptor, nicotinic, beta 1 (muscle)",GO:0005887//integral component of plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane;GO:0045202//synapse;GO:0030054//cell junction,"GO:0042391//regulation of membrane potential;GO:0006936//muscle contraction;GO:0055085//transmembrane transport;GO:0006812//cation transport;GO:0034220//ion transmembrane transport;GO:0035095//behavioral response to nicotine;GO:0007271//synaptic transmission, cholinergic;GO:0007165//signal transduction;GO:0007274//neuromuscular synaptic transmission;GO:0048747//muscle fiber development;GO:0050877//neurological system process;GO:0001941//postsynaptic membrane organization",GO:0015276//ligand-gated ion channel activity;GO:0015267//channel activity;GO:0042166//acetylcholine binding;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity,K04812//Neuroactive ligand-receptor interaction
114034,81,0,7,71,48,0,38,135,25,0,94,0,"TOE1;target of EGR1, member 1 (nuclear)",GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005730//nucleolus,-,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
114044,0,69,67,61,181,0,0,375,29,0,507,1,MCM3AP-AS1;MCM3AP antisense RNA 1,-,-,-,-
114088,0,0,0,0,0,18,0,0,31,0,12,0,TRIM9;tripartite motif containing 9,GO:0008021//synaptic vesicle;GO:0030425//dendrite;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016079//synaptic vesicle exocytosis;GO:0016567//protein ubiquitination;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0035544//negative regulation of SNARE complex assembly,GO:0042803//protein homodimerization activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0000149//SNARE binding;GO:0008270//zinc ion binding,-
1141,0,0,0,0,0,0,1,0,36,0,2,0,"CHRNB2;cholinergic receptor, nicotinic, beta 2 (neuronal)",GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0005892//acetylcholine-gated channel complex,"GO:0006811//ion transport;GO:0008306//associative learning;GO:0006816//calcium ion transport;GO:0001508//action potential;GO:0007626//locomotory behavior;GO:0042220//response to cocaine;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0007271//synaptic transmission, cholinergic;GO:0050890//cognition;GO:0035176//social behavior;GO:0042053//regulation of dopamine metabolic process;GO:0021771//lateral geniculate nucleus development;GO:0051899//membrane depolarization;GO:0008542//visual learning;GO:0006939//smooth muscle contraction;GO:0019233//sensory perception of pain;GO:0021562//vestibulocochlear nerve development;GO:0007613//memory;GO:0007601//visual perception;GO:0045759//negative regulation of action potential;GO:0035094//response to nicotine;GO:0042320//regulation of circadian sleep/wake cycle, REM sleep;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0001661//conditioned taste aversion;GO:0007612//learning;GO:0045471//response to ethanol;GO:0021952//central nervous system projection neuron axonogenesis;GO:0014059//regulation of dopamine secretion;GO:0050877//neurological system process;GO:0033603//positive regulation of dopamine secretion;GO:0007605//sensory perception of sound;GO:0030890//positive regulation of B cell proliferation;GO:0035095//behavioral response to nicotine;GO:0060084//synaptic transmission involved in micturition;GO:0001666//response to hypoxia;GO:0034220//ion transmembrane transport;GO:0048814//regulation of dendrite morphogenesis;GO:0045188//regulation of circadian sleep/wake cycle, non-REM sleep;GO:0007268//synaptic transmission;GO:0051963//regulation of synapse assembly;GO:0051291//protein heterooligomerization;GO:0021631//optic nerve morphogenesis;GO:0007165//signal transduction;GO:0042113//B cell activation",GO:0015276//ligand-gated ion channel activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity;GO:0008144//drug binding;GO:0042166//acetylcholine binding,K04813//Cholinergic synapse;Nicotine addiction;Neuroactive ligand-receptor interaction
114112,109,0,0,0,13,0,0,0,0,0,0,0,TXNRD3;thioredoxin reductase 3,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process;GO:0030154//cell differentiation,GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0004791//thioredoxin-disulfide reductase activity,K00384//Selenocompound metabolism;Pyrimidine metabolism;Two-component system
114131,0,0,0,0,1,0,0,0,5,0,0,0,UCN3;urocortin 3,GO:0005615//extracellular space;GO:0043196//varicosity;GO:0043679//axon terminus,GO:0071456//cellular response to hypoxia;GO:0031669//cellular response to nutrient levels;GO:0035902//response to immobilization stress;GO:0007586//digestion;GO:0009749//response to glucose;GO:0032024//positive regulation of insulin secretion;GO:0045838//positive regulation of membrane potential;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0042594//response to starvation;GO:0051412//response to corticosterone,GO:0005179//hormone activity,-
114132,82,0,52,0,0,9,0,0,23,0,9,0,SIGLEC11;sialic acid binding Ig-like lectin 11,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
114134,5,0,0,0,23,0,60,0,47,0,0,0,"SLC2A13;solute carrier family 2 (facilitated glucose transporter), member 13",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0022891//substrate-specific transmembrane transporter activity,-
1142,1,0,0,0,0,0,0,0,12,0,11,312,"CHRNB3;cholinergic receptor, nicotinic, beta 3 (neuronal)",GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0005892//acetylcholine-gated channel complex;GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0030054//cell junction,"GO:0006812//cation transport;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0051291//protein heterooligomerization;GO:0055085//transmembrane transport;GO:0007271//synaptic transmission, cholinergic",GO:0015267//channel activity;GO:0042166//acetylcholine binding;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0008144//drug binding,K04814//Neuroactive ligand-receptor interaction
114294,0,0,0,0,42,2,0,71,32,0,0,0,"LACTB;lactamase, beta",GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
114299,77,0,0,7,0,13,13,0,0,0,9,371,PALM2;paralemmin 2,GO:0005886//plasma membrane,GO:0008360//regulation of cell shape,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
1143,0,0,0,0,0,0,0,57,50,0,0,1,"CHRNB4;cholinergic receptor, nicotinic, beta 4 (neuronal)",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0005892//acetylcholine-gated channel complex;GO:0016021//integral component of membrane,"GO:0007268//synaptic transmission;GO:0060084//synaptic transmission involved in micturition;GO:0006812//cation transport;GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0006940//regulation of smooth muscle contraction;GO:0007165//signal transduction;GO:0007271//synaptic transmission, cholinergic;GO:0035095//behavioral response to nicotine;GO:0001508//action potential;GO:0006939//smooth muscle contraction;GO:0046928//regulation of neurotransmitter secretion;GO:0007626//locomotory behavior",GO:0015464//acetylcholine receptor activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015276//ligand-gated ion channel activity,K04815//Cholinergic synapse;Neuroactive ligand-receptor interaction
114327,23,0,0,7,0,12,0,0,63,0,0,0,EFHC1;EF-hand domain (C-terminal) containing 1,GO:0005930//axoneme;GO:0043025//neuronal cell body,-,GO:0008022//protein C-terminus binding;GO:0005509//calcium ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
114335,0,0,0,0,0,0,0,0,16,0,0,0,"CGB1;chorionic gonadotropin, beta polypeptide 1",GO:0005576//extracellular region,-,GO:0005179//hormone activity,-
114336,0,0,0,0,0,1,0,0,0,0,0,0,"CGB2;chorionic gonadotropin, beta polypeptide 2",GO:0005576//extracellular region,-,GO:0005179//hormone activity,-
1144,0,0,0,0,0,0,0,0,74,92,12,0,"CHRND;cholinergic receptor, nicotinic, delta (muscle)",GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane,GO:0048630//skeletal muscle tissue growth;GO:0007165//signal transduction;GO:0006810//transport;GO:0050881//musculoskeletal movement;GO:0050905//neuromuscular process;GO:0006812//cation transport;GO:0006936//muscle contraction;GO:0042391//regulation of membrane potential;GO:0007268//synaptic transmission,GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0042166//acetylcholine binding,K04816//Neuroactive ligand-receptor interaction
1145,0,285,163,246,485,0,36,533,38,154,733,0,"CHRNE;cholinergic receptor, nicotinic, epsilon (muscle)",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0005892//acetylcholine-gated channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction,"GO:0042391//regulation of membrane potential;GO:0006936//muscle contraction;GO:0007271//synaptic transmission, cholinergic;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0006810//transport;GO:0006812//cation transport",GO:0008324//cation transmembrane transporter activity;GO:0015464//acetylcholine receptor activity;GO:0004889//acetylcholine-activated cation-selective channel activity,K04817//Neuroactive ligand-receptor interaction
114548,0,0,0,0,0,0,0,12,60,140,0,1,"NLRP3;NLR family, pyrin domain containing 3",GO:0005829//cytosol;GO:0072559//NLRP3 inflammasome complex;GO:0005737//cytoplasm,"GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0032611//interleukin-1 beta production;GO:0006952//defense response;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002674//negative regulation of acute inflammatory response;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009595//detection of biotic stimulus;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0051607//defense response to virus;GO:0032621//interleukin-18 production;GO:0006954//inflammatory response;GO:0044546//NLRP3 inflammasome complex assembly;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0071222//cellular response to lipopolysaccharide;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:0006915//apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0050728//negative regulation of inflammatory response",GO:0005524//ATP binding;GO:0042834//peptidoglycan binding;GO:0005515//protein binding,K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
114569,0,0,0,19,70,0,0,1,28,320,7,0,"MAL2;mal, T-cell differentiation protein 2 (gene/pseudogene)",GO:0012505//endomembrane system;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0048471//perinuclear region of cytoplasm,-,GO:0005515//protein binding,-
114571,1,0,0,0,0,27,23,0,12,0,0,0,"SLC22A9;solute carrier family 22 (organic anion transporter), member 9",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport,GO:0015301//anion:anion antiporter activity;GO:0015347//sodium-independent organic anion transmembrane transporter activity,-
1146,1,0,0,0,0,57,0,16,0,234,13,0,"CHRNG;cholinergic receptor, nicotinic, gamma (muscle)",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0005892//acetylcholine-gated channel complex;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0042391//regulation of membrane potential;GO:0006936//muscle contraction;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0006810//transport,GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity;GO:0015267//channel activity,K04818//Neuroactive ligand-receptor interaction
114609,0,0,0,0,27,0,1,0,61,0,0,0,TIRAP;toll-interleukin 1 receptor (TIR) domain containing adaptor protein,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0032587//ruffle membrane,GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0071221//cellular response to bacterial lipopeptide;GO:0006954//inflammatory response;GO:0045088//regulation of innate immune response;GO:0032738//positive regulation of interleukin-15 production;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090073//positive regulation of protein homodimerization activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0030890//positive regulation of B cell proliferation;GO:0044130//negative regulation of growth of symbiont in host;GO:0032648//regulation of interferon-beta production;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:2000340//positive regulation of chemokine (C-X-C motif) ligand 1 production;GO:0032496//response to lipopolysaccharide;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0030099//myeloid cell differentiation;GO:0050830//defense response to Gram-positive bacterium;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0032757//positive regulation of interleukin-8 production;GO:0032735//positive regulation of interleukin-12 production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0071223//cellular response to lipoteichoic acid;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0035665//TIRAP-dependent toll-like receptor 4 signaling pathway;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0046330//positive regulation of JNK cascade;GO:0034142//toll-like receptor 4 signaling pathway,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0035663//Toll-like receptor 2 binding;GO:0035662//Toll-like receptor 4 binding;GO:0030674//protein binding, bridging;GO:0005080//protein kinase C binding",K05403//NF-kappa B signaling pathway;Pertussis;Tuberculosis;Toll-like receptor signaling pathway
114625,0,119,97,68,126,0,48,0,0,0,35,0,ERMAP;erythroblast membrane-associated protein (Scianna blood group),GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
114659,0,0,0,0,0,0,3,0,37,0,7,0,LRRC37B;leucine rich repeat containing 37B,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,-,-,K06838//Axon guidance
1147,0,0,0,28,13,0,0,0,14,0,0,7,CHUK;conserved helix-loop-helix ubiquitous kinase,GO:0005634//nucleus;GO:0008385//IkappaB kinase complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex,"GO:0050852//T cell receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007252//I-kappaB phosphorylation;GO:0071356//cellular response to tumor necrosis factor;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042475//odontogenesis of dentin-containing tooth;GO:0007595//lactation;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0009615//response to virus;GO:0002011//morphogenesis of an epithelial sheet;GO:0048015//phosphatidylinositol-mediated signaling;GO:0060749//mammary gland alveolus development;GO:0006955//immune response;GO:0033598//mammary gland epithelial cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009636//response to toxic substance;GO:0032481//positive regulation of type I interferon production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0006468//protein phosphorylation;GO:0033194//response to hydroperoxide;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0003009//skeletal muscle contraction;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0030316//osteoclast differentiation;GO:0043200//response to amino acid;GO:0007266//Rho protein signal transduction;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0034166//toll-like receptor 10 signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0002224//toll-like receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042493//response to drug",GO:0008384//IkappaB kinase activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0097110//scaffold protein binding,K04467//Chronic myeloid leukemia;Apoptosis;T cell receptor signaling pathway;Herpes simplex infection;MAPK signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;NF-kappa B signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Small cell lung cancer;Toll-like receptor signaling pathway;Prostate cancer;Hepatitis C;Cytosolic DNA-sensing pathway;Adipocytokine signaling pathway;Toxoplasmosis;Osteoclast differentiation;Measles;Acute myeloid leukemia;HTLV-I infection;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;NOD-like receptor signaling pathway;Shigellosis
114757,0,0,0,0,0,0,0,0,7,0,3,0,CYGB;cytoglobin,GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0043025//neuronal cell body,GO:0015671//oxygen transport;GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process,GO:0005344//oxygen transporter activity;GO:0005506//iron ion binding;GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0019825//oxygen binding,-
114769,0,0,0,0,0,0,0,0,8,0,0,0,"CARD16;caspase recruitment domain family, member 16",-,GO:0042981//regulation of apoptotic process;GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,K01370//Salmonella infection;Cytosolic DNA-sensing pathway;Amyotrophic lateral sclerosis (ALS);Legionellosis;Pertussis;Influenza A;NOD-like receptor signaling pathway
114770,0,0,0,0,0,1,0,0,35,0,1,0,PGLYRP2;peptidoglycan recognition protein 2,GO:0016020//membrane;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome,GO:0050727//regulation of inflammatory response;GO:0009253//peptidoglycan catabolic process;GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production;GO:0044117//growth of symbiont in host;GO:0045087//innate immune response;GO:0001519//peptide amidation;GO:0002221//pattern recognition receptor signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response,GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0016019//peptidoglycan receptor activity;GO:0008270//zinc ion binding;GO:0042834//peptidoglycan binding,-
114771,0,0,0,0,0,18,0,66,17,0,10,0,PGLYRP3;peptidoglycan recognition protein 3,GO:0005622//intracellular;GO:0005576//extracellular region;GO:0016020//membrane,GO:0044117//growth of symbiont in host;GO:0045087//innate immune response;GO:0002221//pattern recognition receptor signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response;GO:0009253//peptidoglycan catabolic process;GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production,GO:0008270//zinc ion binding;GO:0042834//peptidoglycan binding;GO:0016019//peptidoglycan receptor activity;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity,-
114780,0,0,0,0,0,3,64,0,63,123,7,0,PKD1L2;polycystic kidney disease 1-like 2,GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0007218//neuropeptide signaling pathway,GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding,-
114781,63,0,0,0,27,16,30,0,45,0,27,68,BTBD9;BTB (POZ) domain containing 9,-,"GO:1900242//regulation of synaptic vesicle endocytosis;GO:0007155//cell adhesion;GO:0042748//circadian sleep/wake cycle, non-REM sleep;GO:0050951//sensory perception of temperature stimulus;GO:0042428//serotonin metabolic process;GO:0060586//multicellular organismal iron ion homeostasis;GO:0008344//adult locomotory behavior;GO:0007616//long-term memory",-,-
114783,17,0,0,1,0,0,0,26,43,0,14,0,LMTK3;lemur tyrosine kinase 3,GO:0016021//integral component of membrane,GO:0010923//negative regulation of phosphatase activity;GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
114784,285,0,0,0,0,61,29,0,164,149,57,0,CSMD2;CUB and Sushi multiple domains 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K04011//Complement and coagulation cascades;Tuberculosis;Legionellosis;Hematopoietic cell lineage;Malaria;Leishmaniasis;K14616//Vitamin digestion and absorption
114785,0,0,0,16,0,18,0,1,10,1,8,302,MBD6;methyl-CpG binding domain protein 6,GO:0005634//nucleus;GO:0010369//chromocenter,-,GO:0003677//DNA binding;GO:0003682//chromatin binding,-
114786,0,0,0,0,0,0,0,0,19,0,0,0,"XKR4;XK, Kell blood group complex subunit-related family, member 4",GO:0016021//integral component of membrane,-,-,-
114787,0,29,0,10,0,13,0,0,18,0,0,0,GPRIN1;G protein regulated inducer of neurite outgrowth 1,GO:0005886//plasma membrane;GO:0030426//growth cone,GO:0031175//neuron projection development,GO:0051219//phosphoprotein binding,-
114788,0,0,0,0,6,43,101,0,98,226,0,350,CSMD3;CUB and Sushi multiple domains 3,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K04011//Tuberculosis;Legionellosis;Complement and coagulation cascades;Leishmaniasis;Malaria;Hematopoietic cell lineage
114789,0,0,0,1,0,22,0,62,24,0,17,0,"SLC25A25;solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25",GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle,GO:0070588//calcium ion transmembrane transport;GO:0060612//adipose tissue development;GO:0046034//ATP metabolic process;GO:0002021//response to dietary excess;GO:0014823//response to activity;GO:0035264//multicellular organism growth;GO:0045333//cellular respiration;GO:0032094//response to food;GO:0043010//camera-type eye development,GO:0005509//calcium ion binding,-
114790,0,0,0,0,0,24,35,0,38,0,18,0,STK11IP;serine/threonine kinase 11 interacting protein,GO:0043231//intracellular membrane-bounded organelle;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm,GO:0008104//protein localization,GO:0019901//protein kinase binding,K06841//Axon guidance
114791,0,0,0,12,43,28,0,0,28,0,0,0,"TUBGCP5;tubulin, gamma complex associated protein 5",GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0008274//gamma-tubulin ring complex;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007020//microtubule nucleation,GO:0008017//microtubule binding,K01557//Metabolic pathways;Tyrosine metabolism;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01769//Purine metabolism
114792,0,0,0,0,0,11,36,0,59,0,9,0,KLHL32;kelch-like family member 32,-,-,-,-
114793,0,0,0,0,0,0,25,0,1,0,0,0,FMNL2;formin-like 2,GO:0005737//cytoplasm,GO:0030866//cortical actin cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization,GO:0017048//Rho GTPase binding;GO:0003779//actin binding,K04512//Wnt signaling pathway
114794,0,42,24,0,0,0,33,82,33,27,14,0,ELFN2;extracellular leucine-rich repeat and fibronectin type III domain containing 2,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0010923//negative regulation of phosphatase activity,GO:0004864//protein phosphatase inhibitor activity;GO:0019902//phosphatase binding,K06850//Axon guidance
114795,0,0,0,0,0,35,17,39,43,0,0,266,TMEM132B;transmembrane protein 132B,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
114796,0,18,0,0,17,0,88,42,76,13,0,0,PSMG3-AS1;PSMG3 antisense RNA 1 (head to head),-,-,-,-
114798,0,0,0,0,0,0,0,0,34,0,0,0,"SLITRK1;SLIT and NTRK-like family, member 1",GO:0016021//integral component of membrane,GO:0042592//homeostatic process;GO:0007409//axonogenesis;GO:0030534//adult behavior;GO:0035264//multicellular organism growth,-,K06839//Axon guidance;K06838//Axon guidance
114799,219,0,0,0,63,6,0,0,39,0,20,1,ESCO1;establishment of sister chromatid cohesion N-acetyltransferase 1,GO:0000785//chromatin;GO:0005654//nucleoplasm,GO:0006275//regulation of DNA replication;GO:0000278//mitotic cell cycle;GO:0034421//post-translational protein acetylation;GO:0007062//sister chromatid cohesion,"GO:0046872//metal ion binding;GO:0016746//transferase activity, transferring acyl groups",-
114800,0,0,0,0,0,20,0,0,50,0,0,0,CCDC85A;coiled-coil domain containing 85A,-,-,-,-
114801,0,0,0,0,0,0,0,0,31,0,0,0,TMEM200A;transmembrane protein 200A,GO:0016021//integral component of membrane,-,-,-
114803,96,2,0,22,21,0,26,0,20,146,0,4,"MYSM1;Myb-like, SWIRM and MPN domains 1",GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0006508//proteolysis",GO:0003677//DNA binding;GO:0032403//protein complex binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0008237//metallopeptidase activity;GO:0046872//metal ion binding;GO:0042393//histone binding;GO:0004843//ubiquitin-specific protease activity;GO:0004221//ubiquitin thiolesterase activity,-
114804,0,0,1,10,7,0,21,56,13,0,22,0,RNF157;ring finger protein 157,-,-,GO:0008270//zinc ion binding,K10604//Ubiquitin mediated proteolysis
114805,0,0,0,0,0,14,0,0,0,137,0,0,GALNT13;polypeptide N-acetylgalactosaminyltransferase 13,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
114814,194,552,779,1459,2258,30,105,79,60,0,976,0,"GNRHR2;gonadotropin-releasing hormone (type 2) receptor 2, pseudogene",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0097211//cellular response to gonadotropin-releasing hormone,GO:0004968//gonadotropin-releasing hormone receptor activity,K04280//GnRH signaling pathway;Neuroactive ligand-receptor interaction
114815,96,0,0,0,0,15,42,0,63,115,0,0,SORCS1;sortilin-related VPS10 domain containing receptor 1,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity;GO:0005515//protein binding,K12388//Lysosome;Neurotrophin signaling pathway
114818,0,0,0,0,0,8,11,0,52,0,0,1,KLHL29;kelch-like family member 29,-,-,-,-
114819,0,0,0,28,11,0,0,0,13,0,10,0,"CROCCP3;ciliary rootlet coiled-coil, rootletin pseudogene 3",-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion
114821,0,0,0,0,0,0,20,0,42,0,9,0,"ZBED9;zinc finger, BED-type containing 9",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0015074//DNA integration",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity,-
114822,42,0,0,0,0,10,32,1,0,0,0,0,"RHPN1;rhophilin, Rho GTPase binding protein 1",-,GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction,GO:0005083//small GTPase regulator activity,-
114823,69,76,19,89,122,0,50,40,0,0,31,0,LENG8;leukocyte receptor cluster (LRC) member 8,-,-,GO:0005515//protein binding,-
114824,0,0,0,0,0,0,43,0,8,0,0,0,PNMA5;paraneoplastic Ma antigen family member 5,-,GO:0043065//positive regulation of apoptotic process,-,K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction
114825,93,29,17,6,47,21,0,0,8,0,0,0,PWWP2A;PWWP domain containing 2A,-,-,GO:0005515//protein binding,K00558//Folate biosynthesis;Cysteine and methionine metabolism;Metabolic pathways
114826,0,0,0,0,40,0,16,0,50,0,16,0,SMYD4;SET and MYND domain containing 4,-,GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0046872//metal ion binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
114827,129,32,78,16,75,0,1,0,81,4,36,0,FHAD1;forkhead-associated (FHA) phosphopeptide binding domain 1,-,-,-,-
114836,0,0,0,0,0,1,0,0,40,0,3,0,SLAMF6;SLAM family member 6,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,GO:0004872//receptor activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
114876,0,1,1,1,29,2,27,0,53,0,0,0,OSBPL1A;oxysterol binding protein-like 1A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005730//nucleolus,GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0016192//vesicle-mediated transport,GO:0015485//cholesterol binding;GO:0005515//protein binding;GO:0005543//phospholipid binding,-
114879,0,0,0,3,1,0,40,67,41,0,5,0,OSBPL5;oxysterol binding protein-like 5,GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008203//cholesterol metabolic process;GO:0030301//cholesterol transport;GO:0006893//Golgi to plasma membrane transport,GO:0015485//cholesterol binding;GO:0008142//oxysterol binding,-
114880,0,1,0,5,15,14,21,0,68,0,13,0,OSBPL6;oxysterol binding protein-like 6,GO:0097038//perinuclear endoplasmic reticulum;GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0006869//lipid transport,GO:0008289//lipid binding;GO:0005515//protein binding,-
114881,0,0,1,0,0,0,1,98,52,0,7,0,OSBPL7;oxysterol binding protein-like 7,GO:0005776//autophagic vacuole;GO:0097038//perinuclear endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0071397//cellular response to cholesterol;GO:0006869//lipid transport;GO:1901800//positive regulation of proteasomal protein catabolic process,GO:0015485//cholesterol binding;GO:0005515//protein binding,-
114882,85,43,0,29,54,1,0,0,36,0,11,0,OSBPL8;oxysterol binding protein-like 8,GO:0016020//membrane;GO:0031965//nuclear membrane,GO:0006869//lipid transport;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0030336//negative regulation of cell migration;GO:0090204//protein localization to nuclear pore;GO:0045444//fat cell differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0010891//negative regulation of sequestering of triglyceride,GO:0015485//cholesterol binding,-
114883,182,2,86,32,164,30,23,60,50,0,1,0,OSBPL9;oxysterol binding protein-like 9,GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0031902//late endosome membrane,GO:0006869//lipid transport,GO:0008289//lipid binding,-
114884,0,20,0,41,44,14,0,171,26,0,94,1,OSBPL10;oxysterol binding protein-like 10,-,GO:0006869//lipid transport,GO:0015485//cholesterol binding,-
114885,0,0,0,7,11,0,0,0,80,0,0,0,OSBPL11;oxysterol binding protein-like 11,GO:0005794//Golgi apparatus;GO:0031902//late endosome membrane,GO:0010890//positive regulation of sequestering of triglyceride;GO:0006869//lipid transport;GO:0045444//fat cell differentiation,GO:0008289//lipid binding,-
114897,0,0,0,0,0,0,54,0,43,0,3,0,C1QTNF1;C1q and tumor necrosis factor related protein 1,GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0005887//integral component of plasma membrane,GO:0010544//negative regulation of platelet activation;GO:2000860//positive regulation of aldosterone secretion;GO:0051897//positive regulation of protein kinase B signaling;GO:0043410//positive regulation of MAPK cascade;GO:0090331//negative regulation of platelet aggregation;GO:0051260//protein homooligomerization;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070208//protein heterotrimerization;GO:0010906//regulation of glucose metabolic process;GO:0010628//positive regulation of gene expression,GO:0005518//collagen binding;GO:0005515//protein binding,K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus;K01227//Other glycan degradation
114898,0,0,0,0,0,0,0,0,27,0,11,0,C1QTNF2;C1q and tumor necrosis factor related protein 2,GO:0005581//collagen trimer;GO:0005615//extracellular space,GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0000187//activation of MAPK activity;GO:0051260//protein homooligomerization;GO:0070208//protein heterotrimerization;GO:0046321//positive regulation of fatty acid oxidation,GO:0005102//receptor binding;GO:0042802//identical protein binding,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
114899,0,0,0,0,0,0,25,0,0,0,0,0,C1QTNF3;C1q and tumor necrosis factor related protein 3,GO:0005581//collagen trimer;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane,GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:1900165//negative regulation of interleukin-6 secretion;GO:0070206//protein trimerization;GO:0045444//fat cell differentiation;GO:0010629//negative regulation of gene expression;GO:0035356//cellular triglyceride homeostasis;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0050728//negative regulation of inflammatory response;GO:0050715//positive regulation of cytokine secretion;GO:0070165//positive regulation of adiponectin secretion;GO:0045721//negative regulation of gluconeogenesis,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus
1149,0,0,0,8,0,0,0,0,19,0,0,0,CIDEA;cell death-inducing DFFA-like effector a,GO:0005739//mitochondrion;GO:0005811//lipid particle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005740//mitochondrial envelope,"GO:0032720//negative regulation of tumor necrosis factor production;GO:0006915//apoptotic process;GO:1900118//negative regulation of execution phase of apoptosis;GO:0019915//lipid storage;GO:0042981//regulation of apoptotic process;GO:1902510//regulation of apoptotic DNA fragmentation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0001659//temperature homeostasis;GO:0050995//negative regulation of lipid catabolic process;GO:0008219//cell death;GO:0050710//negative regulation of cytokine secretion;GO:0006629//lipid metabolic process;GO:0035634//response to stilbenoid;GO:0006355//regulation of transcription, DNA-templated;GO:0010890//positive regulation of sequestering of triglyceride",GO:0042803//protein homodimerization activity,K02310//Apoptosis
114904,0,0,1,0,0,0,0,0,9,0,0,0,C1QTNF6;C1q and tumor necrosis factor related protein 6,GO:0005615//extracellular space;GO:0005581//collagen trimer,GO:0070208//protein heterotrimerization,GO:0042802//identical protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K07296//Type II diabetes mellitus;Adipocytokine signaling pathway;PPAR signaling pathway;K01227//Other glycan degradation;K11447//Transcriptional misregulation in cancer
114905,0,0,0,0,18,0,30,99,0,0,0,0,C1QTNF7;C1q and tumor necrosis factor related protein 7,GO:0005615//extracellular space;GO:0005581//collagen trimer,GO:0051260//protein homooligomerization,-,K07296//PPAR signaling pathway;Adipocytokine signaling pathway;Type II diabetes mellitus
114907,0,0,0,6,42,0,15,65,29,0,8,0,FBXO32;F-box protein 32,GO:0030018//Z disc;GO:0005730//nucleolus,GO:0071549//cellular response to dexamethasone stimulus;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
114908,0,2,0,7,47,6,0,199,17,0,19,0,TMEM123;transmembrane protein 123,GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0070267//oncosis,GO:0004872//receptor activity,K06546//Lysosome
114926,7,21,0,27,48,22,9,107,13,0,12,0,SMIM19;small integral membrane protein 19,GO:0016021//integral component of membrane,-,-,-
114928,0,0,0,0,0,0,0,8,0,0,0,0,GPRASP2;G protein-coupled receptor associated sorting protein 2,-,-,-,K04574//Amyotrophic lateral sclerosis (ALS)
114932,0,83,0,63,267,0,21,0,0,0,0,0,MRFAP1L1;Morf4 family associated protein 1-like 1,-,-,GO:0005515//protein binding,-
114960,0,0,0,0,0,16,0,0,20,0,0,0,"TSGA13;testis specific, 13",-,-,-,-
114971,64,411,213,362,455,23,40,182,41,312,394,139,"PTPMT1;protein tyrosine phosphatase, mitochondrial 1",GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0046855//inositol phosphate dephosphorylation;GO:0032049//cardiolipin biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process,"GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008962//phosphatidylglycerophosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity",-
114984,0,27,0,0,0,0,0,0,0,0,0,0,FLYWCH2;FLYWCH family member 2,-,-,GO:0044822//poly(A) RNA binding,-
114987,0,0,0,1,17,53,0,2,41,0,6,0,WDR31;WD repeat domain 31,-,-,-,K12857//Spliceosome
114990,0,0,0,0,0,4,0,0,4,7,0,0,VASN;vasorin,GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0010719//negative regulation of epithelial to mesenchymal transition,GO:0050431//transforming growth factor beta binding,K07523//Axon guidance
114991,100,0,1,5,1,11,0,49,75,0,23,0,ZNF618;zinc finger protein 618,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
115,0,0,0,0,9,17,15,1,51,0,4,0,ADCY9;adenylate cyclase 9,GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0045087//innate immune response;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034199//activation of protein kinase A activity;GO:0006833//water transport;GO:0007165//signal transduction,GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0005524//ATP binding,K08049//Gastric acid secretion;Vibrio cholerae infection;Melanogenesis;Bile secretion;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;GABAergic synapse;Cholinergic synapse;HTLV-I infection;Purine metabolism;Glutamatergic synapse;Vascular smooth muscle contraction;Vasopressin-regulated water reabsorption;Oocyte meiosis;Morphine addiction;Pancreatic secretion;Progesterone-mediated oocyte maturation;Chemokine signaling pathway;GnRH signaling pathway;Gap junction
115004,0,0,0,0,0,0,0,0,11,0,0,0,MB21D1;Mab-21 domain containing 1,GO:0005829//cytosol,GO:0071360//cellular response to exogenous dsRNA;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0032481//positive regulation of type I interferon production;GO:0009190//cyclic nucleotide biosynthetic process;GO:0002230//positive regulation of defense response to virus by host;GO:0002218//activation of innate immune response,GO:0003677//DNA binding;GO:0061501//cyclic-GMP-AMP synthase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005525//GTP binding,-
115019,0,0,0,0,0,0,24,0,114,0,22,0,"SLC26A9;solute carrier family 26 (anion exchanger), member 9",GO:0016324//apical plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:1902476//chloride transmembrane transport;GO:0006821//chloride transport;GO:0006885//regulation of pH;GO:0006811//ion transport;GO:1902358//sulfate transmembrane transport;GO:0006820//anion transport;GO:0010628//positive regulation of gene expression;GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport,GO:0051117//ATPase binding;GO:0015106//bicarbonate transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity,K14706//Mineral absorption
115024,0,21,0,10,21,0,0,0,26,0,0,0,"NT5C3B;5'-nucleotidase, cytosolic IIIB",GO:0005737//cytoplasm,GO:0016311//dephosphorylation;GO:0009117//nucleotide metabolic process,GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008253//5'-nucleotidase activity;GO:0000287//magnesium ion binding,K01081//Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
115098,0,0,0,0,0,18,0,0,10,0,0,0,CCDC124;coiled-coil domain containing 124,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0030496//midbody;GO:0005886//plasma membrane,GO:0051301//cell division;GO:0007049//cell cycle,GO:0044822//poly(A) RNA binding,K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
115106,0,0,0,11,0,0,11,11,10,0,0,0,"HAUS1;HAUS augmin-like complex, subunit 1",GO:0070652//HAUS complex;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0051297//centrosome organization;GO:0007067//mitotic nuclear division;GO:0051225//spindle assembly,GO:0005515//protein binding,-
115110,0,29,16,26,97,0,0,59,56,0,89,0,LOC115110;uncharacterized LOC115110,-,-,-,K13744//Bacterial invasion of epithelial cells;K06236//Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction;K06641//HTLV-I infection;Cell cycle - yeast;Cell cycle;p53 signaling pathway;K11447//Transcriptional misregulation in cancer
115111,0,0,0,0,0,19,19,0,59,0,18,0,"SLC26A7;solute carrier family 26 (anion exchanger), member 7",GO:0005737//cytoplasm;GO:0055038//recycling endosome membrane;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:1902476//chloride transmembrane transport;GO:0008272//sulfate transport;GO:0006821//chloride transport;GO:0006811//ion transport;GO:0019532//oxalate transport;GO:0006820//anion transport;GO:1902358//sulfate transmembrane transport;GO:0015701//bicarbonate transport;GO:0001696//gastric acid secretion;GO:0055085//transmembrane transport,GO:0015106//bicarbonate transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0005254//chloride channel activity,K13962//Gastric acid secretion
115123,0,0,0,0,0,0,0,0,1,4,0,0,"MARCH3;membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase",GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0005768//endosome;GO:0005764//lysosome,GO:0006897//endocytosis;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
115196,81,0,0,3,0,0,12,0,24,1,19,0,ZNF554;zinc finger protein 554,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1152,0,96,6,11,115,0,5,128,29,0,0,0,"CKB;creatine kinase, brain",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0030644//cellular chloride ion homeostasis;GO:0006600//creatine metabolic process;GO:0016310//phosphorylation,GO:0005515//protein binding;GO:0004111//creatine kinase activity;GO:0005524//ATP binding,K00933//Arginine and proline metabolism;Metabolic pathways
115201,0,1,1,1,18,0,31,0,21,0,0,0,"ATG4A;autophagy related 4A, cysteine peptidase",GO:0005737//cytoplasm,GO:0006508//proteolysis;GO:0015031//protein transport;GO:0006914//autophagy,GO:0008234//cysteine-type peptidase activity,K08342//Regulation of autophagy
115207,0,0,0,12,0,9,26,26,19,0,0,584,KCTD12;potassium channel tetramerization domain containing 12,GO:0043235//receptor complex;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0070062//extracellular vesicular exosome;GO:0045211//postsynaptic membrane,GO:0051260//protein homooligomerization;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0044822//poly(A) RNA binding,-
115209,0,25,42,29,136,0,0,70,55,0,23,0,OMA1;OMA1 zinc metallopeptidase,GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0006006//glucose metabolic process;GO:0034982//mitochondrial protein processing;GO:0097009//energy homeostasis;GO:0002024//diet induced thermogenesis;GO:0006629//lipid metabolic process;GO:0042407//cristae formation;GO:0006950//response to stress;GO:0010637//negative regulation of mitochondrial fusion,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
115265,72,0,0,0,0,32,24,0,29,0,0,0,DDIT4L;DNA-damage-inducible transcript 4-like,GO:0005737//cytoplasm,GO:0009968//negative regulation of signal transduction,-,K08270//mTOR signaling pathway
115273,0,0,0,0,0,0,0,0,8,0,0,0,"RAB42;RAB42, member RAS oncogene family",GO:0016020//membrane,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
115286,66,0,0,1,0,0,0,0,17,0,0,0,"SLC25A26;solute carrier family 25 (S-adenosylmethionine carrier), member 26",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:1901962//S-adenosyl-L-methionine transmembrane transport,GO:0000095//S-adenosyl-L-methionine transmembrane transporter activity,-
115290,169,15,2,0,0,3,13,9,28,0,2,0,FBXO17;F-box protein 17,GO:0019005//SCF ubiquitin ligase complex,-,GO:0001948//glycoprotein binding;GO:0005515//protein binding,-
115294,0,139,1,132,236,16,36,0,8,0,4,0,PCMTD1;protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1,GO:0005737//cytoplasm,GO:0006479//protein methylation,GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,-
1153,0,0,0,0,0,0,0,0,0,0,17,0,CIRBP;cold inducible RNA binding protein,GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0009409//response to cold;GO:0048255//mRNA stabilization;GO:0045727//positive regulation of translation;GO:0009411//response to UV;GO:0017148//negative regulation of translation;GO:0034063//stress granule assembly,GO:0070181//small ribosomal subunit rRNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030371//translation repressor activity;GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding,-
115350,0,0,0,0,0,0,2,0,42,0,4,0,FCRL1;Fc receptor-like 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
115352,0,0,0,8,0,0,31,7,8,0,0,0,FCRL3;Fc receptor-like 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
115353,0,23,0,6,30,1,0,60,40,0,0,0,LRRC42;leucine rich repeat containing 42,-,-,-,-
115361,0,0,0,0,20,0,20,0,32,0,3,40,GBP4;guanylate binding protein 4,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
115362,93,0,0,0,0,0,0,0,20,1,4,0,GBP5;guanylate binding protein 5,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process,GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
115399,11,0,7,0,17,0,12,212,50,0,14,0,LRRC56;leucine rich repeat containing 56,-,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
1154,0,0,0,0,0,29,0,2,27,0,0,58,CISH;cytokine inducible SH2-containing protein,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0016567//protein ubiquitination;GO:0009968//negative regulation of signal transduction;GO:0035556//intracellular signal transduction;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0001558//regulation of cell growth,GO:0005515//protein binding,K04701//Jak-STAT signaling pathway
115416,111,11,0,24,31,0,0,0,2,0,0,0,MALSU1;mitochondrial assembly of ribosomal large subunit 1,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0042273//ribosomal large subunit biogenesis;GO:0070130//negative regulation of mitochondrial translation,-,-
115426,0,38,1,24,70,30,0,0,83,0,2,0,"UHRF2;ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase",GO:0005720//nuclear heterochromatin;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0051865//protein autoubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0071158//positive regulation of cell cycle arrest;GO:0030154//cell differentiation;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0016567//protein ubiquitination;GO:0051726//regulation of cell cycle,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0042393//histone binding,-
1155,0,0,0,0,0,24,0,0,0,0,0,0,TBCB;tubulin folding cofactor B,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton,GO:0051084//'de novo' posttranslational protein folding;GO:0030154//cell differentiation;GO:0007399//nervous system development;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding,K04648//Vasopressin-regulated water reabsorption;Huntington's disease
115509,5,0,0,0,9,13,15,77,28,0,1,0,ZNF689;zinc finger protein 689,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0035914//skeletal muscle cell differentiation;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
115548,93,41,0,5,32,19,0,1,2,0,4,550,FCHO2;FCH domain only 2,GO:0030136//clathrin-coated vesicle;GO:0005886//plasma membrane;GO:0005905//coated pit,GO:0048268//clathrin coat assembly;GO:0072583//clathrin-mediated endocytosis;GO:0072659//protein localization to plasma membrane;GO:0010324//membrane invagination,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0001786//phosphatidylserine binding",K12804//NOD-like receptor signaling pathway
115557,0,0,0,0,0,0,17,0,18,0,6,5,ARHGEF25;Rho guanine nucleotide exchange factor (GEF) 25,GO:0030017//sarcomere;GO:0005886//plasma membrane;GO:0030016//myofibril;GO:0005829//cytosol,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
115560,0,0,0,0,28,14,36,0,40,0,0,0,ZNF501;zinc finger protein 501,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
115572,0,0,0,0,9,0,7,0,16,0,0,0,"FAM46B;family with sequence similarity 46, member B",-,-,-,-
115584,71,0,0,0,0,2,0,0,20,0,12,0,"SLC5A11;solute carrier family 5 (sodium/inositol cotransporter), member 11",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008643//carbohydrate transport;GO:0006814//sodium ion transport;GO:0006915//apoptotic process;GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
115653,0,0,0,0,0,0,26,0,13,0,0,0,"KIR3DL3;killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K07980//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
115677,143,0,0,0,12,11,0,0,3,7,0,0,NOSTRIN;nitric oxide synthase trafficking,GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005634//nucleus;GO:0005856//cytoskeleton,"GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0046209//nitric oxide metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006897//endocytosis;GO:0050999//regulation of nitric-oxide synthase activity",GO:0003677//DNA binding;GO:0005515//protein binding,K04710//Sphingolipid metabolism;Metabolic pathways;K05729//Regulation of actin cytoskeleton;Pancreatic cancer;K07365//T cell receptor signaling pathway;Axon guidance;Pathogenic Escherichia coli infection;ErbB signaling pathway
115701,72,0,0,0,1,0,20,26,44,272,1,0,ALPK2;alpha-kinase 2,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
115703,0,0,0,0,0,20,0,0,0,0,21,302,ARHGAP33;Rho GTPase activating protein 33,GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0032855//positive regulation of Rac GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0030675//Rac GTPase activator activity;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K08878//Pathways in cancer;Chronic myeloid leukemia;K04450//Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Influenza A;Alcoholism
115704,0,0,0,0,0,13,0,85,25,0,9,0,EVI5L;ecotropic viral integration site 5-like,-,GO:0033126//positive regulation of GTP catabolic process;GO:0032851//positive regulation of Rab GTPase activity,GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K06102//Tight junction
115708,0,1,0,0,2,0,20,0,53,0,8,0,TRMT61A;tRNA methyltransferase 61 homolog A (S. cerevisiae),GO:0031515//tRNA (m1A) methyltransferase complex;GO:0005634//nucleus,GO:0030488//tRNA methylation,GO:0016429//tRNA (adenine-N1-)-methyltransferase activity,-
115727,316,0,0,0,25,25,2,0,19,0,4,0,RASGRP4;RAS guanyl releasing protein 4,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0016049//cell growth;GO:0007264//small GTPase mediated signal transduction;GO:0046579//positive regulation of Ras protein signal transduction;GO:0009991//response to extracellular stimulus;GO:0030099//myeloid cell differentiation;GO:0032320//positive regulation of Ras GTPase activity;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0008283//cell proliferation;GO:0007202//activation of phospholipase C activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0019992//diacylglycerol binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0005509//calcium ion binding;GO:0030742//GTP-dependent protein binding,K12363//MAPK signaling pathway
115749,0,0,0,0,0,19,0,0,0,69,7,0,C12orf56;chromosome 12 open reading frame 56,-,-,-,-
115752,0,58,1,37,78,16,41,0,28,0,5,0,DIS3L;DIS3 like exosome 3'-5' exoribonuclease,GO:0000177//cytoplasmic exosome (RNase complex),"GO:0016075//rRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic",GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003723//RNA binding;GO:0019899//enzyme binding,K12585//RNA degradation
115761,0,0,0,0,0,0,0,0,25,0,0,0,ARL11;ADP-ribosylation factor-like 11,GO:0005622//intracellular,GO:0002244//hematopoietic progenitor cell differentiation;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding,-
115795,0,0,0,0,0,0,0,0,32,0,0,0,FANCD2OS;FANCD2 opposite strand,-,-,-,K10891//Fanconi anemia pathway
1158,0,0,0,0,0,0,0,0,18,0,0,0,"CKM;creatine kinase, muscle",GO:0005829//cytosol,GO:0016310//phosphorylation;GO:0006600//creatine metabolic process;GO:0044281//small molecule metabolic process;GO:0046314//phosphocreatine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0005524//ATP binding;GO:0004111//creatine kinase activity,K00933//Metabolic pathways;Arginine and proline metabolism
115811,0,0,0,0,0,18,0,0,0,0,0,0,IQCD;IQ motif containing D,-,-,-,-
115817,0,26,26,0,12,0,0,0,25,0,36,0,DHRS1;dehydrogenase/reductase (SDR family) member 1,GO:0005783//endoplasmic reticulum;GO:0005743//mitochondrial inner membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
115825,0,20,0,12,33,0,23,0,31,154,13,316,WDFY2;WD repeat and FYVE domain containing 2,-,-,GO:0046872//metal ion binding,K12182//Phagosome;Endocytosis
115861,0,0,6,0,0,0,0,18,0,0,0,0,NXNL1;nucleoredoxin-like 1,GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane,GO:0045494//photoreceptor cell maintenance,-,-
1159,0,0,0,0,2,0,19,0,2,0,0,0,"CKMT1B;creatine kinase, mitochondrial 1B",-,-,-,K00933//Metabolic pathways;Arginine and proline metabolism
115908,0,0,0,0,0,0,16,1,0,0,0,0,CTHRC1;collagen triple helix repeat containing 1,GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,"GO:0060122//inner ear receptor stereocilium organization;GO:0032092//positive regulation of protein binding;GO:0090177//establishment of planar polarity involved in neural tube closure;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0033690//positive regulation of osteoblast proliferation;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0043932//ossification involved in bone remodeling;GO:0016477//cell migration;GO:0045669//positive regulation of osteoblast differentiation;GO:0090103//cochlea morphogenesis",GO:0005109//frizzled binding;GO:0017147//Wnt-protein binding,K06823//Protein digestion and absorption;K06237//Pathways in cancer;ECM-receptor interaction;Focal adhesion;Protein digestion and absorption;Small cell lung cancer;Amoebiasis;K13649//Endocytosis
115939,0,13,19,28,12,0,11,51,11,0,102,0,"TSR3;TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)",-,GO:0006364//rRNA processing,-,-
115950,0,0,0,0,0,18,39,0,24,0,0,0,ZNF653;zinc finger protein 653,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K09234//Transcriptional misregulation in cancer
115992,0,0,0,0,0,14,0,0,15,0,14,0,RNF166;ring finger protein 166,-,-,GO:0008270//zinc ion binding,-
116,0,0,0,0,0,10,0,0,11,66,0,0,ADCYAP1;adenylate cyclase activating polypeptide 1 (pituitary),GO:0043195//terminal bouton;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0021983//pituitary gland development;GO:0031175//neuron projection development;GO:0007267//cell-cell signaling;GO:0070445//regulation of oligodendrocyte progenitor proliferation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045471//response to ethanol;GO:0019933//cAMP-mediated signaling;GO:0007218//neuropeptide signaling pathway;GO:0042594//response to starvation;GO:0007190//activation of adenylate cyclase activity;GO:0060253//negative regulation of glial cell proliferation;GO:0045909//positive regulation of vasodilation;GO:0001662//behavioral fear response;GO:0045860//positive regulation of protein kinase activity;GO:0010976//positive regulation of neuron projection development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001541//ovarian follicle development;GO:0060124//positive regulation of growth hormone secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell proliferation;GO:0032880//regulation of protein localization;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0032854//positive regulation of Rap GTPase activity;GO:0043267//negative regulation of potassium ion transport;GO:0071385//cellular response to glucocorticoid stimulus;GO:0045786//negative regulation of cell cycle;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0019233//sensory perception of pain;GO:0001821//histamine secretion;GO:0046034//ATP metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0034259//negative regulation of Rho GTPase activity",GO:0005184//neuropeptide hormone activity;GO:0016521//pituitary adenylate cyclase activating polypeptide activity;GO:0051428//peptide hormone receptor binding;GO:0005057//receptor signaling protein activity;GO:0005102//receptor binding,-
1160,0,0,0,8,0,0,0,1,23,0,11,0,"CKMT2;creatine kinase, mitochondrial 2 (sarcomeric)",GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0006600//creatine metabolic process;GO:0016310//phosphorylation;GO:0034641//cellular nitrogen compound metabolic process;GO:0006936//muscle contraction;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0004111//creatine kinase activity,K00933//Arginine and proline metabolism;Metabolic pathways
116028,0,0,0,0,0,0,17,0,0,0,0,0,RMI2;RecQ mediated genome instability 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006260//DNA replication,GO:0003677//DNA binding,K15365//Fanconi anemia pathway
116039,0,0,0,0,0,0,0,0,44,0,0,0,OSR2;odd-skipped related transciption factor 2,GO:0005634//nucleus,"GO:2000543//positive regulation of gastrulation;GO:0030501//positive regulation of bone mineralization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042474//middle ear morphogenesis;GO:0030154//cell differentiation;GO:0042476//odontogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0048793//pronephros development;GO:0060349//bone morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0033687//osteoblast proliferation;GO:0001656//metanephros development;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0072498//embryonic skeletal joint development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0009790//embryo development;GO:0061029//eyelid development in camera-type eye;GO:0010628//positive regulation of gene expression;GO:0060021//palate development;GO:0002062//chondrocyte differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042733//embryonic digit morphogenesis;GO:0060322//head development;GO:0001823//mesonephros development;GO:0060272//embryonic skeletal joint morphogenesis",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
116064,0,0,0,59,99,14,0,0,36,0,0,0,LRRC58;leucine rich repeat containing 58,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
116068,0,0,0,0,16,0,30,0,0,0,0,0,"LYSMD3;LysM, putative peptidoglycan-binding, domain containing 3",GO:0016021//integral component of membrane,-,-,-
116071,65,0,0,0,0,0,0,0,19,0,0,0,"BATF2;basic leucine zipper transcription factor, ATF-like 2",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0042832//defense response to protozoan;GO:0006355//regulation of transcription, DNA-templated;GO:0043011//myeloid dendritic cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
116085,0,0,0,0,0,0,30,0,11,0,7,0,"SLC22A12;solute carrier family 22 (organic anion/urate transporter), member 12",GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane,GO:0015747//urate transport;GO:0015849//organic acid transport;GO:0019725//cellular homeostasis;GO:0055085//transmembrane transport;GO:0042493//response to drug;GO:0046415//urate metabolic process,GO:0015143//urate transmembrane transporter activity;GO:0030165//PDZ domain binding,-
116092,0,0,0,0,0,0,0,4,0,0,0,0,"DNTTIP1;deoxynucleotidyltransferase, terminal, interacting protein 1",GO:0005730//nucleolus;GO:0005634//nucleus,-,-,-
116093,0,0,0,0,0,0,0,0,20,0,0,0,DIRC1;disrupted in renal carcinoma 1,-,-,-,-
1161,0,24,0,0,17,0,0,0,0,0,0,0,ERCC8;excision repair cross-complementation group 8,GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0000109//nucleotide-excision repair complex;GO:0005634//nucleus;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex,GO:0006974//cellular response to DNA damage stimulus;GO:0051865//protein autoubiquitination;GO:0006281//DNA repair;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006289//nucleotide-excision repair;GO:0045739//positive regulation of DNA repair;GO:0009411//response to UV;GO:0000209//protein polyubiquitination;GO:0010165//response to X-ray;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006979//response to oxidative stress,GO:0032403//protein complex binding;GO:0008094//DNA-dependent ATPase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0003678//DNA helicase activity,K10570//Ubiquitin mediated proteolysis;Nucleotide excision repair
116113,18,0,0,0,8,6,0,56,28,1,10,0,FOXP4;forkhead box P4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0048617//embryonic foregut morphogenesis;GO:0007507//heart development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901250//negative regulation of lung goblet cell differentiation;GO:0061140//lung secretory cell differentiation",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
116115,0,1,0,0,0,0,0,0,79,0,8,0,ZNF526;zinc finger protein 526,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
116123,0,0,0,0,0,0,54,0,5,0,0,0,FMO9P;flavin containing monooxygenase 9 pseudogene,-,-,-,K00485//Microbial metabolism in diverse environments;Drug metabolism - cytochrome P450;Methane metabolism
116135,0,0,0,0,0,0,0,61,23,0,0,0,LRRC3B;leucine rich repeat containing 3B,GO:0016021//integral component of membrane,-,-,K06839//Axon guidance;K06850//Axon guidance
116138,0,63,1,23,41,0,0,1,22,0,2,0,KLHDC3;kelch domain containing 3,GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0007131//reciprocal meiotic recombination,GO:0003682//chromatin binding;GO:0005515//protein binding,K14966//Herpes simplex infection
116143,0,0,0,0,0,0,0,0,52,0,8,0,WDR92;WD repeat domain 92,-,GO:0006915//apoptotic process;GO:0034968//histone lysine methylation,GO:0035064//methylated histone binding;GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism
116150,1,62,0,24,78,26,0,0,32,0,0,1,NUS1;nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0055092//sterol homeostasis;GO:0001525//angiogenesis;GO:0030154//cell differentiation;GO:0006486//protein glycosylation;GO:0032367//intracellular cholesterol transport,"GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0005515//protein binding",-
116151,0,85,2,150,367,9,0,0,5,0,1,0,"FAM210B;family with sequence similarity 210, member B",GO:0016021//integral component of membrane,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
116154,32,0,0,0,6,31,0,80,61,0,9,3,PHACTR3;phosphatase and actin regulator 3,GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0005634//nucleus,GO:0043086//negative regulation of catalytic activity,GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity,-
116159,0,0,0,0,0,2,0,0,38,0,0,0,CYYR1;cysteine/tyrosine-rich 1,GO:0016021//integral component of membrane,-,-,-
116173,0,0,0,0,0,0,0,51,24,49,3,0,CMTM5;CKLF-like MARVEL transmembrane domain containing 5,GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
116179,0,0,0,0,0,0,0,0,2,0,1,0,TGM7;transglutaminase 7,-,GO:0018149//peptide cross-linking,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding,-
116224,0,0,0,2,12,8,0,0,35,0,12,0,FAM122A;family with sequence similarity 122A,-,-,-,-
116225,0,53,0,0,1,49,9,124,10,0,3,0,"ZMYND19;zinc finger, MYND-type containing 19",GO:0005737//cytoplasm;GO:0045202//synapse;GO:0005886//plasma membrane,-,GO:0046872//metal ion binding,K02870//Ribosome
116228,0,17,0,9,50,0,0,0,0,0,6,0,COX20;COX20 cytochrome C oxidase assembly factor,GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
116236,0,0,0,0,0,46,18,29,33,0,1,0,ABHD15;abhydrolase domain containing 15,GO:0005576//extracellular region;GO:0016020//membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
116238,0,0,0,0,0,0,44,0,0,0,7,0,TLCD1;TLC domain containing 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
116254,0,26,0,8,1,16,0,0,9,0,0,0,GINM1;glycoprotein integral membrane 1,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
116255,0,0,0,0,0,0,0,0,26,0,0,0,MOGAT1;monoacylglycerol O-acyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006651//diacylglycerol biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0006071//glycerol metabolic process,GO:0004144//diacylglycerol O-acyltransferase activity;GO:0003846//2-acylglycerol O-acyltransferase activity,-
116285,66,10,0,6,0,0,2,0,19,0,0,0,ACSM1;acyl-CoA synthetase medium-chain family member 1,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle,GO:0042632//cholesterol homeostasis;GO:0019605//butyrate metabolic process;GO:0015980//energy derivation by oxidation of organic compounds;GO:0018874//benzoate metabolic process;GO:0019395//fatty acid oxidation;GO:0006633//fatty acid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0015645//fatty acid ligase activity;GO:0003996//acyl-CoA ligase activity;GO:0005525//GTP binding;GO:0005524//ATP binding,K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
1163,0,18,0,0,13,0,0,0,0,0,0,0,CKS1B;CDC28 protein kinase regulatory subunit 1B,GO:0005654//nucleoplasm,GO:0000082//G1/S transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0051301//cell division;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle,GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005515//protein binding,K02219//Cell cycle - yeast;Small cell lung cancer;Pathways in cancer
116328,2,132,86,84,66,24,2,21,80,59,51,0,C8orf34;chromosome 8 open reading frame 34,-,-,-,-
116337,0,0,0,0,0,0,4,0,0,0,0,0,PANX3;pannexin 3,GO:0005921//gap junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0034214//protein hexamerization;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0007267//cell-cell signaling,GO:0055077//gap junction hemi-channel activity,-
116362,0,36,0,0,0,0,0,0,0,51,0,0,"RBP7;retinol binding protein 7, cellular",GO:0005737//cytoplasm,GO:0006810//transport,GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0005215//transporter activity,K06210//Metabolic pathways;Nicotinate and nicotinamide metabolism
116369,26,0,0,0,0,30,0,0,21,0,0,0,"SLC26A8;solute carrier family 26 (anion exchanger), member 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:1902476//chloride transmembrane transport;GO:0030154//cell differentiation;GO:0008272//sulfate transport;GO:0006821//chloride transport;GO:0019532//oxalate transport;GO:0007126//meiotic nuclear division;GO:1902358//sulfate transmembrane transport;GO:0006820//anion transport;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0005515//protein binding;GO:0015116//sulfate transmembrane transporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0015301//anion:anion antiporter activity;GO:0005254//chloride channel activity,-
116372,64,0,0,8,0,0,0,64,25,0,9,0,LYPD1;LY6/PLAUR domain containing 1,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,-,-,-
116379,4,0,0,0,0,13,30,0,20,1,13,0,"IL22RA2;interleukin 22 receptor, alpha 2",GO:0005615//extracellular space;GO:0005829//cytosol,GO:0050728//negative regulation of inflammatory response;GO:0019221//cytokine-mediated signaling pathway;GO:0042516//regulation of tyrosine phosphorylation of Stat3 protein,GO:0042018//interleukin-22 receptor activity;GO:0042017//interleukin-22 binding,K05139//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
1164,0,0,0,4,0,0,0,0,0,0,0,0,CKS2;CDC28 protein kinase regulatory subunit 2,-,GO:0008283//cell proliferation;GO:0007127//meiosis I;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity,K02219//Pathways in cancer;Cell cycle - yeast;Small cell lung cancer
116412,66,0,0,0,1,0,0,1,8,0,3,0,ZNF837;zinc finger protein 837,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
116437,0,0,0,0,0,0,0,0,16,0,0,0,LINC01257;long intergenic non-protein coding RNA 1257,-,-,-,-
116441,0,0,0,0,0,0,0,0,34,0,0,0,TM4SF18;transmembrane 4 L six family member 18,GO:0016021//integral component of membrane,-,-,-
116442,0,0,0,1,13,33,0,0,17,0,0,0,"RAB39B;RAB39B, member RAS oncogene family",GO:0005794//Golgi apparatus;GO:0005622//intracellular;GO:0005886//plasma membrane,GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0050808//synapse organization;GO:0015031//protein transport,GO:0005515//protein binding;GO:0005525//GTP binding,-
116443,0,9,0,22,7,0,35,0,49,0,4,0,"GRIN3A;glutamate receptor, ionotropic, N-methyl-D-aspartate 3A",GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body,"GO:0070588//calcium ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0045471//response to ethanol;GO:0006816//calcium ion transport;GO:0060134//prepulse inhibition;GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport;GO:0016358//dendrite development;GO:0048511//rhythmic process",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding;GO:0016594//glycine binding;GO:0042802//identical protein binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0042165//neurotransmitter binding,K05213//Nicotine addiction;Cocaine addiction;Amphetamine addiction;Glutamatergic synapse;Neuroactive ligand-receptor interaction;Alcoholism
116444,0,0,0,0,0,0,30,76,17,0,0,0,"GRIN3B;glutamate receptor, ionotropic, N-methyl-D-aspartate 3B",GO:0043025//neuronal cell body;GO:0045211//postsynaptic membrane;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0030425//dendrite;GO:0030054//cell junction,"GO:0051205//protein insertion into membrane;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0051924//regulation of calcium ion transport",GO:0042165//neurotransmitter binding;GO:0005261//cation channel activity;GO:0030594//neurotransmitter receptor activity;GO:0016594//glycine binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005262//calcium channel activity,K05214//Neuroactive ligand-receptor interaction;Alcoholism;Nicotine addiction;Cocaine addiction;Glutamatergic synapse;Amphetamine addiction
116447,57,0,0,0,0,0,14,0,32,0,7,224,"TOP1MT;topoisomerase (DNA) I, mitochondrial",GO:0005634//nucleus;GO:0031298//replication fork protection complex;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005730//nucleolus,GO:0006265//DNA topological change;GO:0006260//DNA replication;GO:0007059//chromosome segregation;GO:0006200//ATP catabolic process;GO:0006338//chromatin remodeling,GO:0003917//DNA topoisomerase type I activity;GO:0003918//DNA topoisomerase type II (ATP-hydrolyzing) activity;GO:0003677//DNA binding,-
116448,0,0,0,0,0,0,8,0,13,0,0,0,OLIG1;oligodendrocyte transcription factor 1,GO:0005634//nucleus,"GO:0048663//neuron fate commitment;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
116449,0,0,0,0,0,0,0,122,21,0,0,0,CLNK;cytokine-dependent hematopoietic cell linker,GO:0005622//intracellular,GO:0006955//immune response;GO:0009967//positive regulation of signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07361//Fc epsilon RI signaling pathway;Osteoclast differentiation;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity
116461,0,0,0,0,0,28,0,0,0,0,0,0,TSEN15;TSEN15 tRNA splicing endonuclease subunit,GO:0005730//nucleolus,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006397//mRNA processing;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation",GO:0000213//tRNA-intron endonuclease activity,-
116496,58,206,37,288,471,60,0,1,18,0,12,0,"FAM129A;family with sequence similarity 129, member A",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0034976//response to endoplasmic reticulum stress;GO:0045727//positive regulation of translation;GO:0001933//negative regulation of protein phosphorylation;GO:0001934//positive regulation of protein phosphorylation,GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
116512,0,0,47,0,0,0,0,64,0,0,0,0,"MRGPRD;MAS-related GPR, member D",GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
116519,0,0,0,0,0,0,0,0,57,0,0,0,APOA5;apolipoprotein A-V,GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0034362//low-density lipoprotein particle;GO:0005615//extracellular space;GO:0034361//very-low-density lipoprotein particle;GO:0005576//extracellular region,GO:0010898//positive regulation of triglyceride catabolic process;GO:0019433//triglyceride catabolic process;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0031100//organ regeneration;GO:0050996//positive regulation of lipid catabolic process;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0042632//cholesterol homeostasis;GO:0006869//lipid transport;GO:0006641//triglyceride metabolic process;GO:0042246//tissue regeneration;GO:0042157//lipoprotein metabolic process;GO:0010902//positive regulation of very-low-density lipoprotein particle remodeling;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0070328//triglyceride homeostasis;GO:0009725//response to hormone,GO:0031210//phosphatidylcholine binding;GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0008047//enzyme activator activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0070325//lipoprotein particle receptor binding;GO:0060230//lipoprotein lipase activator activity;GO:0035473//lipase binding,K09025//PPAR signaling pathway
116534,0,0,0,0,8,0,20,66,4,0,0,0,"MRGPRE;MAS-related GPR, member E",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
116535,0,0,0,0,0,23,9,0,0,0,0,0,"MRGPRF;MAS-related GPR, member F",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
116540,0,36,0,0,4,0,0,0,0,0,0,0,MRPL53;mitochondrial ribosomal protein L53,GO:0005840//ribosome;GO:0005739//mitochondrion,-,-,-
116541,91,0,0,10,28,0,18,0,13,0,0,0,MRPL54;mitochondrial ribosomal protein L54,GO:0005840//ribosome;GO:0005739//mitochondrion,-,GO:0044822//poly(A) RNA binding,-
116832,0,0,0,0,0,0,0,0,50,0,0,0,RPL39L;ribosomal protein L39-like,GO:0022625//cytosolic large ribosomal subunit,GO:0007283//spermatogenesis;GO:0006412//translation,GO:0003735//structural constituent of ribosome,K02924//Ribosome
116835,0,0,0,0,11,0,25,62,18,0,10,0,HSPA12B;heat shock 70kD protein 12B,-,-,GO:0005524//ATP binding,-
116840,1,0,0,0,1,13,0,0,8,0,0,0,"CNTROB;centrobin, centrosomal BRCA2 interacting protein",GO:0005814//centriole;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0000910//cytokinesis;GO:0051299//centrosome separation;GO:0007099//centriole replication,GO:0019904//protein domain specific binding;GO:0005515//protein binding,-
116841,0,117,22,42,57,12,11,348,35,0,241,1,"SNAP47;synaptosomal-associated protein, 47kDa",GO:0030425//dendrite;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0031083//BLOC-1 complex,GO:0060291//long-term synaptic potentiation,GO:0005515//protein binding,K08509//SNARE interactions in vesicular transport
116842,0,0,0,0,0,0,44,0,11,0,0,0,LEAP2;liver expressed antimicrobial peptide 2,GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
116843,0,0,0,0,0,4,0,0,19,0,0,0,"SLC18B1;solute carrier family 18, subfamily B, member 1",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,K08155//Amphetamine addiction;Dopaminergic synapse;Cocaine addiction;Parkinson's disease;Serotonergic synapse;Alcoholism;Synaptic vesicle cycle
116844,0,0,0,0,0,0,8,0,18,0,16,0,LRG1;leucine-rich alpha-2-glycoprotein 1,GO:0005615//extracellular space;GO:0016020//membrane;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045766//positive regulation of angiogenesis;GO:0050873//brown fat cell differentiation,GO:0005160//transforming growth factor beta receptor binding,-
116931,91,21,0,0,28,15,41,25,132,0,1,0,MED12L;mediator complex subunit 12-like,GO:0016592//mediator complex,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0001104//RNA polymerase II transcription cofactor activity;GO:0008134//transcription factor binding;GO:0008013//beta-catenin binding,-
116966,87,0,0,0,0,18,13,0,111,0,6,0,WDR17;WD repeat domain 17,-,-,-,K04508//Wnt signaling pathway
116969,0,0,0,0,0,0,0,0,0,0,6,0,ART5;ADP-ribosyltransferase 5,GO:0005576//extracellular region;GO:0016020//membrane,GO:0006471//protein ADP-ribosylation,GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0003953//NAD+ nucleosidase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
116983,0,1,0,0,0,0,15,2,2,161,36,1,"ACAP3;ArfGAP with coiled-coil, ankyrin repeat and PH domains 3",-,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12489//Endocytosis
116984,0,25,0,5,69,66,0,18,82,0,0,0,"ARAP2;ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2",GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity,"GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding",K12490//Endocytosis
116985,196,30,37,0,7,56,44,9,15,25,8,0,"ARAP1;ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1",GO:0031410//cytoplasmic vesicle;GO:0005802//trans-Golgi network;GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0001921//positive regulation of receptor recycling;GO:0051270//regulation of cellular component movement;GO:0030037//actin filament reorganization involved in cell cycle;GO:0043089//positive regulation of Cdc42 GTPase activity;GO:0008360//regulation of cell shape;GO:0051497//negative regulation of stress fiber assembly;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051491//positive regulation of filopodium assembly;GO:0032312//regulation of ARF GTPase activity,"GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005100//Rho GTPase activator activity;GO:0005515//protein binding;GO:0031702//type 1 angiotensin receptor binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding",K12490//Endocytosis
116986,0,30,58,23,72,0,17,129,24,120,177,0,"AGAP2;ArfGAP with GTPase domain, ankyrin repeat and PH domain 2",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005634//nucleus,GO:0043524//negative regulation of neuron apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport;GO:0042177//negative regulation of protein catabolic process;GO:0007411//axon guidance,GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding,K12491//Endocytosis
116987,44,32,9,26,34,41,26,50,70,23,12,582,"AGAP1;ArfGAP with GTPase domain, ankyrin repeat and PH domain 1",GO:0005737//cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport;GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0005543//phospholipid binding;GO:0008060//ARF GTPase activator activity;GO:0005525//GTP binding,K12491//Endocytosis
116988,0,0,0,0,5,0,44,0,39,97,15,0,"AGAP3;ArfGAP with GTPase domain, ankyrin repeat and PH domain 3",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0071944//cell periphery;GO:0016020//membrane,"GO:0000060//protein import into nucleus, translocation;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0034614//cellular response to reactive oxygen species;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0008270//zinc ion binding;GO:0031593//polyubiquitin binding;GO:0008060//ARF GTPase activator activity,K12491//Endocytosis
117,0,0,0,0,0,6,0,55,38,0,0,0,ADCYAP1R1;adenylate cyclase activating polypeptide 1 (pituitary) receptor type I,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0007166//cell surface receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030154//cell differentiation,GO:0004872//receptor activity;GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0005515//protein binding,K04587//Neuroactive ligand-receptor interaction
117143,0,1,0,0,0,33,24,4,37,0,9,0,TADA1;transcriptional adaptor 1,GO:0030914//STAGA complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated",GO:0004402//histone acetyltransferase activity;GO:0003713//transcription coactivator activity,-
117144,91,0,0,5,7,19,12,0,8,155,0,0,"CATSPER1;cation channel, sperm associated 1",GO:0036128//CatSper complex;GO:0031514//motile cilium;GO:0005886//plasma membrane,GO:0007338//single fertilization;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0030154//cell differentiation;GO:0034765//regulation of ion transmembrane transport;GO:0035036//sperm-egg recognition;GO:0030317//sperm motility;GO:0051924//regulation of calcium ion transport;GO:0007275//multicellular organismal development;GO:0070588//calcium ion transmembrane transport;GO:0007283//spermatogenesis;GO:0032504//multicellular organism reproduction;GO:0007342//fusion of sperm to egg plasma membrane,GO:0005227//calcium activated cation channel activity;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity,K04856//Calcium signaling pathway;MAPK signaling pathway;K05315//MAPK signaling pathway;K04857//Cardiac muscle contraction;Dilated cardiomyopathy;Serotonergic synapse;Retrograde endocannabinoid signaling;Calcium signaling pathway;Cholinergic synapse;GnRH signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);GABAergic synapse;Vascular smooth muscle contraction;Alzheimer's disease;Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
117145,0,23,0,2,6,0,30,5,24,0,0,0,THEM4;thioesterase superfamily member 4,GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005739//mitochondrion,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0043491//protein kinase B signaling;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006631//fatty acid metabolic process,GO:0016290//palmitoyl-CoA hydrolase activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
117153,0,0,0,0,0,34,0,0,4,0,0,0,MIA2;melanoma inhibitory activity 2,GO:0070971//endoplasmic reticulum exit site;GO:0005576//extracellular region,GO:0042632//cholesterol homeostasis;GO:0070328//triglyceride homeostasis,-,-
117154,0,0,0,0,0,0,0,0,28,0,0,0,DACH2;dachshund family transcription factor 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0046545//development of primary female sexual characteristics;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
117155,1,0,0,0,0,7,0,0,35,0,0,0,"CATSPER2;cation channel, sperm associated 2",GO:0036128//CatSper complex;GO:0031514//motile cilium;GO:0005886//plasma membrane,GO:0007338//single fertilization;GO:0030154//cell differentiation;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0007283//spermatogenesis;GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035036//sperm-egg recognition;GO:0007275//multicellular organismal development;GO:0030317//sperm motility;GO:0032504//multicellular organism reproduction,GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0005227//calcium activated cation channel activity,K04849//Taste transduction;MAPK signaling pathway;Morphine addiction;Type II diabetes mellitus;Dopaminergic synapse;GABAergic synapse;Cholinergic synapse;Nicotine addiction;Serotonergic synapse;Synaptic vesicle cycle;Retrograde endocannabinoid signaling;Calcium signaling pathway
117157,0,43,0,0,0,0,0,0,26,0,0,0,SH2D1B;SH2 domain containing 1B,GO:0005622//intracellular,GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002366//leukocyte activation involved in immune response;GO:0002717//positive regulation of natural killer cell mediated immunity;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032814//regulation of natural killer cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0045089//positive regulation of innate immune response,"GO:0005515//protein binding;GO:0030674//protein binding, bridging",K07989//Natural killer cell mediated cytotoxicity
117166,0,0,0,0,0,14,1,0,0,0,1,0,"WFIKKN1;WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1",GO:0005576//extracellular region,GO:0060021//palate development;GO:0032091//negative regulation of protein binding;GO:0048747//muscle fiber development;GO:0010951//negative regulation of endopeptidase activity;GO:0001501//skeletal system development;GO:0043392//negative regulation of DNA binding,GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades
117177,1,2,28,87,382,14,18,0,134,0,46,1,RAB3IP;RAB3A interacting protein,GO:0036064//ciliary basal body;GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005634//nucleus,GO:0042384//cilium assembly;GO:0032851//positive regulation of Rab GTPase activity;GO:0006893//Golgi to plasma membrane transport;GO:0033365//protein localization to organelle;GO:0006612//protein targeting to membrane,GO:0005515//protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
117178,0,2,0,9,34,0,0,0,79,0,15,0,"SSX2IP;synovial sarcoma, X breakpoint 2 interacting protein",GO:0031252//cell leading edge;GO:0034451//centriolar satellite;GO:0043234//protein complex;GO:0005913//cell-cell adherens junction;GO:0005634//nucleus,GO:0007155//cell adhesion;GO:0051297//centrosome organization;GO:2000145//regulation of cell motility;GO:0035020//regulation of Rac protein signal transduction,GO:0019904//protein domain specific binding;GO:0005515//protein binding,K06085//Adherens junction
117194,0,0,0,0,0,0,0,0,7,0,9,0,"MRGPRX2;MAS-related GPR, member X2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0030431//sleep;GO:0019233//sensory perception of pain;GO:0032467//positive regulation of cytokinesis,GO:0004930//G-protein coupled receptor activity;GO:0042923//neuropeptide binding,-
117195,0,0,0,0,0,0,0,0,19,26,0,2,"MRGPRX3;MAS-related GPR, member X3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
117196,0,0,0,0,0,3,0,0,0,0,0,0,"MRGPRX4;MAS-related GPR, member X4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
117245,74,0,0,0,0,0,0,0,0,0,5,0,"HRASLS5;HRAS-like suppressor family, member 5",-,GO:0008152//metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K00678//Retinol metabolism;Vitamin digestion and absorption
117246,80,0,0,0,30,0,0,0,31,0,12,0,FTSJ3;FtsJ homolog 3 (E. coli),"GO:0005730//nucleolus;GO:0030688//preribosome, small subunit precursor;GO:0005634//nucleus",-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008649//rRNA methyltransferase activity,-
117247,0,0,0,0,0,9,19,22,12,0,0,0,"SLC16A10;solute carrier family 16 (aromatic amino acid transporter), member 10",GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane,GO:0006865//amino acid transport;GO:0015801//aromatic amino acid transport;GO:0006811//ion transport;GO:0055085//transmembrane transport,-,K08187//Protein digestion and absorption
117248,70,0,0,0,0,0,0,0,18,0,0,0,GALNT15;polypeptide N-acetylgalactosaminyltransferase 15,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle,GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030246//carbohydrate binding;GO:0046872//metal ion binding,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
117283,0,0,0,0,0,0,34,0,29,0,0,0,IP6K3;inositol hexakisphosphate kinase 3,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0046488//phosphatidylinositol metabolic process;GO:0006468//protein phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0032958//inositol phosphate biosynthetic process,"GO:0000831//inositol hexakisphosphate 6-kinase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0005524//ATP binding;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity",-
117286,0,0,0,0,0,0,12,0,0,0,0,0,CIB3;calcium and integrin binding family member 3,-,-,GO:0005509//calcium ion binding,K06268//B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation;Long-term potentiation;Tuberculosis;Axon guidance;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;Apoptosis;T cell receptor signaling pathway;Glutamatergic synapse;Amphetamine addiction;MAPK signaling pathway;Natural killer cell mediated cytotoxicity
117289,0,0,47,8,0,11,36,0,11,0,0,0,TAGAP;T-cell activation RhoGTPase activating protein,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity,K08773//Pathways in cancer;Pancreatic cancer
1173,10,34,4,25,97,0,21,52,26,0,0,0,"AP2M1;adaptor-related protein complex 2, mu 1 subunit",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030131//clathrin adaptor complex;GO:0005905//coated pit;GO:0005765//lysosomal membrane,GO:0006897//endocytosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007411//axon guidance;GO:0061024//membrane organization;GO:0007268//synaptic transmission;GO:0050690//regulation of defense response to virus by virus;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016032//viral process;GO:0006886//intracellular protein transport,GO:0005515//protein binding;GO:0005215//transporter activity;GO:0008289//lipid binding,K11826//Huntington's disease;Endocytosis;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
1174,0,28,0,2,19,0,0,0,35,0,0,0,"AP1S1;adaptor-related protein complex 1, sigma 1 subunit",GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0030121//AP-1 adaptor complex;GO:0070062//extracellular vesicular exosome;GO:0005905//coated pit;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0032588//trans-Golgi network membrane,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006898//receptor-mediated endocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0009615//response to virus;GO:0050690//regulation of defense response to virus by virus;GO:0016032//viral process;GO:0006886//intracellular protein transport,GO:0008565//protein transporter activity,K12394//Lysosome
117531,0,0,0,0,0,9,29,0,21,0,4,0,TMC1;transmembrane channel-like 1,GO:0032426//stereocilium bundle tip;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0060117//auditory receptor cell development;GO:0060005//vestibular reflex;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0070588//calcium ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
117532,26,0,0,0,0,24,0,45,50,0,11,0,TMC2;transmembrane channel-like 2,GO:0032426//stereocilium bundle tip;GO:0016021//integral component of membrane,GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0070588//calcium ion transmembrane transport;GO:0060005//vestibular reflex,GO:0005245//voltage-gated calcium channel activity,-
117579,0,0,0,0,0,0,0,0,1,0,0,0,RLN3;relaxin 3,GO:0005576//extracellular region,-,GO:0001664//G-protein coupled receptor binding;GO:0005515//protein binding;GO:0005179//hormone activity,-
117581,0,0,59,0,0,0,1,0,0,0,0,0,TWIST2;twist family bHLH transcription factor 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation",GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
117583,0,0,6,16,48,2,0,0,55,18,20,0,PARD3B;par-3 family cell polarity regulator beta,GO:0012505//endomembrane system;GO:0005923//tight junction;GO:0016020//membrane,GO:0007049//cell cycle;GO:0051301//cell division,-,K04237//Adherens junction;Neuroactive ligand-receptor interaction;Tight junction;Chemokine signaling pathway;Endocytosis
117584,0,0,0,0,0,0,0,0,4,0,0,0,RFFL;ring finger and FYVE-like domain containing E3 ubiquitin protein ligase,GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0010008//endosome membrane;GO:0002947//tumor necrosis factor receptor superfamily complex;GO:0005737//cytoplasm;GO:0055038//recycling endosome membrane;GO:0005829//cytosol;GO:0005764//lysosome,GO:0010762//regulation of fibroblast migration;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis;GO:0032006//regulation of TOR signaling;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0070936//protein K48-linked ubiquitination,GO:0002020//protease binding;GO:0061630//ubiquitin protein ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0016874//ligase activity;GO:0002039//p53 binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K10871//Homologous recombination
1176,0,0,0,8,75,0,0,0,0,219,12,0,"AP3S1;adaptor-related protein complex 3, sigma 1 subunit",GO:0005794//Golgi apparatus;GO:0030659//cytoplasmic vesicle membrane;GO:0030133//transport vesicle;GO:0030123//AP-3 adaptor complex;GO:0030119//AP-type membrane coat adaptor complex,GO:0008089//anterograde axon cargo transport;GO:0048490//anterograde synaptic vesicle transport;GO:0008286//insulin receptor signaling pathway;GO:0006886//intracellular protein transport,GO:0005515//protein binding;GO:0005215//transporter activity;GO:0008565//protein transporter activity,K12399//Lysosome
117608,0,0,0,0,1,0,0,0,34,0,0,0,ZNF354B;zinc finger protein 354B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
1178,0,0,0,0,0,0,0,0,17,0,5,0,CLC;Charcot-Leyden crystal galectin,GO:0005829//cytosol,GO:0002667//regulation of T cell anergy;GO:0002724//regulation of T cell cytokine production;GO:0007275//multicellular organismal development;GO:0070231//T cell apoptotic process;GO:0046006//regulation of activated T cell proliferation,GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0004622//lysophospholipase activity;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process,-
117854,0,0,0,0,0,17,19,0,0,118,0,0,TRIM6;tripartite motif containing 6,GO:0005737//cytoplasm,GO:0070206//protein trimerization,GO:0008270//zinc ion binding,-
1179,0,0,0,0,0,27,0,0,81,179,0,0,CLCA1;chloride channel accessory 1,GO:0042589//zymogen granule membrane;GO:0005615//extracellular space;GO:0005902//microvillus;GO:0005887//integral component of plasma membrane,GO:0071456//cellular response to hypoxia;GO:0006821//chloride transport;GO:0006816//calcium ion transport;GO:0006810//transport;GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity,K05027//Pancreatic secretion;Olfactory transduction
118,0,14,1,43,165,20,0,344,22,0,0,4,ADD1;adducin 1 (alpha),GO:0005886//plasma membrane;GO:0008290//F-actin capping protein complex;GO:0043197//dendritic spine;GO:0014069//postsynaptic density;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0048873//homeostasis of number of cells within a tissue;GO:0020027//hemoglobin metabolic process;GO:0035264//multicellular organism growth;GO:0030036//actin cytoskeleton organization;GO:0051016//barbed-end actin filament capping;GO:0032092//positive regulation of protein binding;GO:0001701//in utero embryonic development;GO:0030218//erythrocyte differentiation;GO:0045766//positive regulation of angiogenesis;GO:0044267//cellular protein metabolic process;GO:0045807//positive regulation of endocytosis;GO:0006884//cell volume homeostasis;GO:0006915//apoptotic process;GO:0071300//cellular response to retinoic acid;GO:0000902//cell morphogenesis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0051017//actin filament bundle assembly;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005198//structural molecule activity;GO:0051015//actin filament binding;GO:0030507//spectrin binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0042608//T cell receptor binding;GO:0008134//transcription factor binding,-
1180,0,0,0,0,0,0,61,0,16,1,13,0,"CLCN1;chloride channel, voltage-sensitive 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0042383//sarcolemma;GO:0034707//chloride channel complex,GO:1902476//chloride transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0044070//regulation of anion transport;GO:0055085//transmembrane transport;GO:0006936//muscle contraction;GO:0019227//neuronal action potential propagation;GO:0034220//ion transmembrane transport;GO:0006810//transport,GO:0030554//adenyl nucleotide binding;GO:0005254//chloride channel activity;GO:0005247//voltage-gated chloride channel activity,-
1181,59,0,0,0,0,6,0,59,40,0,0,0,"CLCN2;chloride channel, voltage-sensitive 2",GO:0034707//chloride channel complex;GO:0005886//plasma membrane,GO:0044070//regulation of anion transport;GO:0055085//transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0060689//cell differentiation involved in salivary gland development;GO:0060041//retina development in camera-type eye;GO:1902476//chloride transmembrane transport,GO:0005247//voltage-gated chloride channel activity;GO:0030554//adenyl nucleotide binding,K05011//Mineral absorption
1182,43,41,0,1,44,0,0,0,17,0,0,0,"CLCN3;chloride channel, voltage-sensitive 3",GO:0030658//transport vesicle membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0031902//late endosome membrane;GO:0031901//early endosome membrane;GO:0012506//vesicle membrane,GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0044070//regulation of anion transport;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0006885//regulation of pH;GO:0048388//endosomal lumen acidification;GO:1902476//chloride transmembrane transport,GO:0005515//protein binding;GO:0005247//voltage-gated chloride channel activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0030165//PDZ domain binding;GO:0015297//antiporter activity;GO:0005254//chloride channel activity;GO:0005524//ATP binding,-
1183,0,0,0,0,0,48,31,66,59,0,39,0,"CLCN4;chloride channel, voltage-sensitive 4",GO:0010008//endosome membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0031902//late endosome membrane,GO:0006821//chloride transport;GO:0044070//regulation of anion transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006810//transport,GO:0015297//antiporter activity;GO:0005524//ATP binding;GO:0005254//chloride channel activity;GO:0005247//voltage-gated chloride channel activity,-
1184,26,0,0,0,0,17,15,0,45,0,0,0,"CLCN5;chloride channel, voltage-sensitive 5",GO:0045177//apical part of cell;GO:0005887//integral component of plasma membrane;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0010008//endosome membrane,GO:0044070//regulation of anion transport;GO:0055085//transmembrane transport;GO:0006897//endocytosis;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007588//excretion,GO:0005254//chloride channel activity;GO:0005524//ATP binding;GO:0015297//antiporter activity;GO:0005247//voltage-gated chloride channel activity,-
118424,103,0,0,0,1,36,17,54,29,0,0,0,"UBE2J2;ubiquitin-conjugating enzyme E2, J2",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K04554//Protein processing in endoplasmic reticulum;Parkinson's disease;Ubiquitin mediated proteolysis
118426,0,0,0,0,0,0,0,0,28,0,2,0,"LOH12CR1;loss of heterozygosity, 12, chromosomal region 1",-,-,-,-
118427,0,0,0,0,0,0,120,0,11,190,4,0,OLFM3;olfactomedin 3,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0005794//Golgi apparatus;GO:0045202//synapse;GO:0030054//cell junction;GO:0005615//extracellular space,GO:0042462//eye photoreceptor cell development,GO:0005515//protein binding,-
118429,70,152,42,68,99,16,0,302,64,193,157,71,ANTXR2;anthrax toxin receptor 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0022414//reproductive process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004872//receptor activity,K06238//ECM-receptor interaction;Protein digestion and absorption;Focal adhesion
118432,0,0,0,0,0,19,0,0,0,0,0,0,RPL29P2;ribosomal protein L29 pseudogene 2,-,-,-,K02905//Ribosome
118442,0,82,2,31,114,0,41,5,13,0,101,0,GPR62;G protein-coupled receptor 62,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
118460,118,18,0,12,7,0,31,0,0,0,3,0,EXOSC6;exosome component 6,GO:0000178//exosome (RNase complex);GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0006364//rRNA processing;GO:0016070//RNA metabolic process;GO:0045190//isotype switching;GO:0016071//mRNA metabolic process;GO:0045006//DNA deamination;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0004532//exoribonuclease activity;GO:0044822//poly(A) RNA binding,K12587//RNA degradation
118461,0,0,0,0,0,0,3,18,41,0,0,0,C10orf71;chromosome 10 open reading frame 71,-,-,-,K15184//Transcriptional misregulation in cancer
118471,0,0,0,0,0,13,0,0,0,0,0,0,PRAP1;proline-rich acidic protein 1,GO:0005576//extracellular region,-,-,K09254//Transcriptional misregulation in cancer;K06641//p53 signaling pathway;Cell cycle - yeast;Cell cycle;HTLV-I infection;K11447//Transcriptional misregulation in cancer
118472,0,0,0,11,62,0,26,40,0,160,40,0,ZNF511;zinc finger protein 511,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
118487,0,0,0,0,23,0,29,0,0,0,12,0,CHCHD1;coiled-coil-helix-coiled-coil-helix domain containing 1,GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
118490,39,0,0,0,0,15,0,1,36,1,10,0,MSS51;MSS51 mitochondrial translational activator,-,GO:0035176//social behavior,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
118491,98,1,0,8,15,0,4,49,52,1,20,0,TTC18;tetratricopeptide repeat domain 18,GO:0070062//extracellular vesicular exosome,-,-,-
1185,0,0,0,0,0,0,0,0,38,66,0,0,"CLCN6;chloride channel, voltage-sensitive 6",GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane,GO:0044070//regulation of anion transport;GO:0006821//chloride transport;GO:0055085//transmembrane transport;GO:0006884//cell volume homeostasis;GO:0007165//signal transduction;GO:0009612//response to mechanical stimulus;GO:0034220//ion transmembrane transport,GO:0005247//voltage-gated chloride channel activity;GO:0015297//antiporter activity;GO:0005524//ATP binding,-
1186,105,0,0,0,0,16,13,2,61,0,14,0,"CLCN7;chloride channel, voltage-sensitive 7",GO:0005765//lysosomal membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0055085//transmembrane transport;GO:0044070//regulation of anion transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0006810//transport;GO:0009268//response to pH,GO:0015297//antiporter activity;GO:0005524//ATP binding;GO:0005254//chloride channel activity;GO:0005247//voltage-gated chloride channel activity,-
118611,0,0,17,0,20,33,0,0,63,0,0,0,C10orf90;chromosome 10 open reading frame 90,GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0010212//response to ionizing radiation;GO:0030308//negative regulation of cell growth;GO:0050821//protein stabilization;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0009411//response to UV,GO:0042826//histone deacetylase binding,-
118663,0,0,0,0,0,0,22,28,26,0,0,0,BTBD16;BTB (POZ) domain containing 16,-,-,-,-
118672,92,0,0,0,0,0,0,0,19,0,0,0,PSTK;phosphoseryl-tRNA kinase,GO:0005739//mitochondrion,GO:0016310//phosphorylation;GO:0001514//selenocysteine incorporation;GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process,GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0016301//kinase activity,K10837//Aminoacyl-tRNA biosynthesis;Selenocompound metabolism
1187,66,0,0,0,0,0,33,17,38,0,0,0,"CLCNKA;chloride channel, voltage-sensitive Ka",GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0006810//transport;GO:0007588//excretion;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0044070//regulation of anion transport,GO:0030554//adenyl nucleotide binding;GO:0046872//metal ion binding;GO:0005247//voltage-gated chloride channel activity,K05018//Collecting duct acid secretion
118738,86,0,0,0,0,0,11,1,13,0,3,0,ZNF488;zinc finger protein 488,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0014003//oligodendrocyte development",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
118788,0,44,41,3,0,26,33,63,48,0,18,1,PIK3AP1;phosphoinositide-3-kinase adaptor protein 1,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane,GO:0034154//toll-like receptor 7 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0050727//regulation of inflammatory response;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0034162//toll-like receptor 9 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway,GO:0042802//identical protein binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding,K12230//B cell receptor signaling pathway
1188,0,0,0,0,0,8,10,1,43,0,0,0,"CLCNKB;chloride channel, voltage-sensitive Kb",GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0044070//regulation of anion transport;GO:0034765//regulation of ion transmembrane transport;GO:0007588//excretion;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport,GO:0005247//voltage-gated chloride channel activity;GO:0046872//metal ion binding;GO:0030554//adenyl nucleotide binding,K05018//Collecting duct acid secretion
118812,66,16,0,18,0,5,0,0,37,0,0,0,MORN4;MORN repeat containing 4,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K04575//Amyotrophic lateral sclerosis (ALS)
118813,0,0,0,0,1,27,2,0,12,0,0,0,"ZFYVE27;zinc finger, FYVE domain containing 27",GO:0005789//endoplasmic reticulum membrane;GO:0032584//growth cone membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0055038//recycling endosome membrane,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008219//cell death;GO:0072659//protein localization to plasma membrane;GO:0031175//neuron projection development,GO:0005515//protein binding;GO:0046872//metal ion binding,K04679//Endocytosis;TGF-beta signaling pathway
118856,0,0,0,0,0,0,1,42,18,0,0,0,MMP21;matrix metallopeptidase 21,GO:0031012//extracellular matrix;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0002244//hematopoietic progenitor cell differentiation,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
118924,0,0,0,6,39,0,0,0,34,0,0,407,"FRA10AC1;fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1",GO:0005634//nucleus,-,GO:0005515//protein binding,-
118932,0,0,0,0,0,0,17,0,23,0,4,0,ANKRD22;ankyrin repeat domain 22,-,-,-,K01052//Steroid biosynthesis;Lysosome
118980,0,0,0,2,15,0,10,29,0,0,0,0,SFXN2;sideroflexin 2,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0055072//iron ion homeostasis,GO:0008324//cation transmembrane transporter activity,K11447//Transcriptional misregulation in cancer;K03351//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
118987,78,0,0,0,2,0,1,0,41,0,0,0,PDZD8;PDZ domain containing 8,GO:0016020//membrane,GO:0016032//viral process;GO:0022604//regulation of cell morphogenesis;GO:0035556//intracellular signal transduction;GO:0007010//cytoskeleton organization,GO:0046872//metal ion binding,-
119,0,0,0,0,0,11,8,0,67,0,30,0,ADD2;adducin 2 (beta),GO:0008290//F-actin capping protein complex;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0051017//actin filament bundle assembly;GO:0006461//protein complex assembly;GO:0030097//hemopoiesis;GO:0030036//actin cytoskeleton organization;GO:0051016//barbed-end actin filament capping;GO:0032092//positive regulation of protein binding,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0030507//spectrin binding;GO:0051015//actin filament binding;GO:0005198//structural molecule activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
119016,0,0,0,7,0,1,0,0,0,72,2,0,"AGAP4;ArfGAP with GTPase domain, ankyrin repeat and PH domain 4",-,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12491//Endocytosis
119032,0,7,2,40,28,0,0,0,15,0,26,0,C10orf32;chromosome 10 open reading frame 32,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer
1191,0,34,5,13,9,21,0,0,34,0,18,0,CLU;clusterin,GO:0034366//spherical high-density lipoprotein particle;GO:0042583//chromaffin granule;GO:0005783//endoplasmic reticulum;GO:0097440//apical dendrite;GO:0048471//perinuclear region of cytoplasm;GO:0031012//extracellular matrix;GO:0097418//neurofibrillary tangle;GO:0005829//cytosol;GO:0031093//platelet alpha granule lumen;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031966//mitochondrial membrane,"GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0051788//response to misfolded protein;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0043691//reverse cholesterol transport;GO:1902847//regulation of neuronal signal transduction;GO:1902430//negative regulation of beta-amyloid formation;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0097193//intrinsic apoptotic signaling pathway;GO:0050821//protein stabilization;GO:0001836//release of cytochrome c from mitochondria;GO:0000902//cell morphogenesis;GO:0061518//microglial cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0061077//chaperone-mediated protein folding;GO:0032463//negative regulation of protein homooligomerization;GO:1902949//positive regulation of tau-protein kinase activity;GO:0006629//lipid metabolic process;GO:0045087//innate immune response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:1902998//positive regulation of neurofibrillary tangle assembly;GO:0006956//complement activation;GO:0006958//complement activation, classical pathway;GO:0017038//protein import;GO:1901214//regulation of neuron death;GO:0009615//response to virus;GO:0032286//central nervous system myelin maintenance;GO:1901216//positive regulation of neuron death;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030168//platelet activation;GO:0001774//microglial cell activation;GO:0007596//blood coagulation;GO:0051131//chaperone-mediated protein complex assembly;GO:1900221//regulation of beta-amyloid clearance;GO:1902004//positive regulation of beta-amyloid formation;GO:0002576//platelet degranulation",GO:0016887//ATPase activity;GO:0031625//ubiquitin protein ligase binding;GO:0051787//misfolded protein binding;GO:0005515//protein binding,-
119180,0,0,1,0,0,0,0,0,0,0,0,0,LYZL2;lysozyme-like 2,GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process,GO:0003796//lysozyme activity,-
1193,0,0,0,0,0,0,0,0,32,0,0,0,CLIC2;chloride intracellular channel 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0034707//chloride channel complex;GO:0005622//intracellular,GO:1902476//chloride transmembrane transport;GO:0007165//signal transduction;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0055114//oxidation-reduction process;GO:0006810//transport;GO:0051099//positive regulation of binding;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0044070//regulation of anion transport,GO:0004602//glutathione peroxidase activity;GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding;GO:0005254//chloride channel activity;GO:0004364//glutathione transferase activity,-
119369,0,0,0,0,0,0,0,0,9,0,0,0,NUDT9P1;nudix (nucleoside diphosphate linked moiety X)-type motif 9 pseudogene 1,-,-,-,K13988//Purine metabolism
119385,0,0,0,0,0,29,0,0,0,0,0,0,AGAP11;ankyrin repeat and GTPase domain Arf GTPase activating protein 11,-,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity,GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K12491//Endocytosis
119391,0,35,0,5,1,0,16,0,50,0,0,85,GSTO2;glutathione S-transferase omega 2,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:1901687//glutathione derivative biosynthetic process;GO:0019852//L-ascorbic acid metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0071243//cellular response to arsenic-containing substance;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process,GO:0050610//methylarsonate reductase activity;GO:0016491//oxidoreductase activity;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0004364//glutathione transferase activity,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
119392,0,0,0,0,1,0,0,0,28,0,0,0,SFR1;SWI5-dependent recombination repair 1,GO:0032798//Swi5-Sfr1 complex;GO:0005634//nucleus,GO:0000724//double-strand break repair via homologous recombination,GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;K11447//Transcriptional misregulation in cancer
119395,15,0,0,0,0,0,0,0,8,0,0,0,CALHM3;calcium homeostasis modulator 3,GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
119437,0,0,0,0,0,0,0,95,16,0,0,0,"CTAGE7P;CTAGE family, member 7, pseudogene",-,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
119467,0,0,0,0,0,0,0,0,21,0,0,33,CLRN3;clarin 3,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
1195,0,0,0,15,17,0,0,0,31,0,0,0,CLK1;CDC-like kinase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0018107//peptidyl-threonine phosphorylation;GO:0046777//protein autophosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0008283//cell proliferation;GO:0043484//regulation of RNA splicing,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity,K08823//Legionellosis
119504,0,1,0,2,82,0,0,1,15,107,0,0,ANAPC16;anaphase promoting complex subunit 16,GO:0005680//anaphase-promoting complex;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0007067//mitotic nuclear division,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
119548,0,0,0,0,0,0,0,0,16,0,0,0,PNLIPRP3;pancreatic lipase-related protein 3,GO:0005576//extracellular region,GO:0016042//lipid catabolic process,GO:0004806//triglyceride lipase activity,K14076//Glycerolipid metabolism;Metabolic pathways
119559,0,1,0,0,0,14,0,0,43,0,0,0,SFXN4;sideroflexin 4,GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055072//iron ion homeostasis,GO:0008324//cation transmembrane transporter activity,-
119587,0,0,0,0,0,0,0,0,55,0,0,0,"CPXM2;carboxypeptidase X (M14 family), member 2",GO:0005615//extracellular space;GO:0031012//extracellular matrix,GO:0006508//proteolysis;GO:0007155//cell adhesion,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,-
1196,69,0,2,0,0,69,0,81,29,0,0,0,CLK2;CDC-like kinase 2,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0010212//response to ionizing radiation;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043484//regulation of RNA splicing;GO:0032526//response to retinoic acid;GO:0045721//negative regulation of gluconeogenesis,GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity,K08823//Legionellosis
119679,0,0,0,0,0,0,0,0,5,0,0,0,"OR52J3;olfactory receptor, family 52, subfamily J, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
119682,0,0,0,0,0,19,0,0,0,0,0,0,"OR51L1;olfactory receptor, family 51, subfamily L, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
119692,0,0,0,0,0,0,0,0,6,0,0,0,"OR51S1;olfactory receptor, family 51, subfamily S, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
119695,0,0,0,0,0,6,0,0,0,0,0,0,"OR52R1;olfactory receptor, family 52, subfamily R, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1197,0,0,1,0,0,0,9,0,11,0,8,0,"CLK2P;CDC-like kinase 2, pseudogene",-,-,-,K08823//Legionellosis
119710,0,0,0,2,9,0,0,0,0,0,0,0,C11orf74;chromosome 11 open reading frame 74,-,-,-,-
119764,0,0,0,0,0,0,0,0,8,0,0,0,"OR4X2;olfactory receptor, family 4, subfamily X, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
119765,0,0,0,0,0,0,27,0,0,0,0,0,"OR4B1;olfactory receptor, family 4, subfamily B, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
119772,0,0,0,0,0,0,20,0,0,0,0,0,"OR52M1;olfactory receptor, family 52, subfamily M, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
119774,0,0,0,0,0,0,1,28,0,0,0,0,"OR52K2;olfactory receptor, family 52, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
1198,0,0,0,0,15,0,0,70,28,0,26,0,CLK3;CDC-like kinase 3,GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0001669//acrosomal vesicle;GO:0005634//nucleus,GO:0043484//regulation of RNA splicing;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity,K08823//Legionellosis
120,0,43,0,182,538,13,0,0,53,0,10,16,ADD3;adducin 3 (gamma),GO:0005886//plasma membrane;GO:0016020//membrane;GO:0000794//condensed nuclear chromosome;GO:0005938//cell cortex;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction,-,GO:0005200//structural constituent of cytoskeleton;GO:0005516//calmodulin binding;GO:0003779//actin binding,-
1200,0,0,0,0,0,13,0,96,89,107,0,0,TPP1;tripeptidyl peptidase I,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0042470//melanosome;GO:0043202//lysosomal lumen;GO:0005764//lysosome,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0007040//lysosome organization;GO:0006508//proteolysis;GO:0045453//bone resorption;GO:0007399//nervous system development;GO:0044267//cellular protein metabolic process;GO:0030855//epithelial cell differentiation;GO:0050885//neuromuscular process controlling balance;GO:0043171//peptide catabolic process;GO:0008219//cell death;GO:0006629//lipid metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030163//protein catabolic process,GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0008240//tripeptidyl-peptidase activity;GO:0042277//peptide binding;GO:0004175//endopeptidase activity,K01279//Lysosome
120066,0,0,0,0,0,0,0,0,12,0,0,0,"OR5P3;olfactory receptor, family 5, subfamily P, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
1201,1,1,0,0,0,0,0,0,0,0,0,1,"CLN3;ceroid-lipofuscinosis, neuronal 3",GO:0005795//Golgi stack;GO:0005739//mitochondrion;GO:0005776//autophagic vacuole;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0005901//caveola;GO:0005634//nucleus;GO:0005764//lysosome;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm,GO:0007042//lysosomal lumen acidification;GO:0030163//protein catabolic process;GO:0042133//neurotransmitter metabolic process;GO:0035752//lysosomal lumen pH elevation;GO:0016236//macroautophagy;GO:0043524//negative regulation of neuron apoptotic process;GO:0016485//protein processing;GO:0006684//sphingomyelin metabolic process;GO:0061024//membrane organization;GO:0006520//cellular amino acid metabolic process;GO:0047496//vesicle transport along microtubule;GO:0001575//globoside metabolic process;GO:0006678//glucosylceramide metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0006898//receptor-mediated endocytosis;GO:0042987//amyloid precursor protein catabolic process;GO:0016242//negative regulation of macroautophagy;GO:0006672//ceramide metabolic process;GO:0000046//autophagic vacuole fusion;GO:0045861//negative regulation of proteolysis;GO:0001508//action potential;GO:0008219//cell death;GO:0043066//negative regulation of apoptotic process;GO:0015809//arginine transport;GO:0008306//associative learning;GO:0051480//cytosolic calcium ion homeostasis;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:0007040//lysosome organization;GO:0007034//vacuolar transport;GO:0006681//galactosylceramide metabolic process,GO:0005515//protein binding;GO:0051082//unfolded protein binding,K12389//Lysosome
120103,0,0,0,4,0,18,3,0,68,83,6,0,"SLC36A4;solute carrier family 36 (proton/amino acid symporter), member 4",GO:0016021//integral component of membrane,GO:0015808//L-alanine transport;GO:0015827//tryptophan transport;GO:0055085//transmembrane transport;GO:0015824//proline transport,GO:0015293//symporter activity,K14209//Protein digestion and absorption
120114,148,39,0,0,0,18,134,0,128,1,0,5,FAT3;FAT atypical cadherin 3,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
120146,0,0,0,0,0,1,1,0,0,0,0,0,TRIM64;tripartite motif containing 64,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
120224,1,0,0,0,0,0,25,0,24,0,0,0,TMEM45B;transmembrane protein 45B,GO:0016021//integral component of membrane,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
120227,118,0,0,0,38,0,0,0,0,0,0,0,"CYP2R1;cytochrome P450, family 2, subfamily R, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0008202//steroid metabolic process;GO:0042359//vitamin D metabolic process;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0044281//small molecule metabolic process,"GO:0004497//monooxygenase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",K07419//Metabolic pathways;Steroid biosynthesis
120237,0,0,0,0,0,13,0,0,7,0,0,0,DBX1;developing brain homeobox 1,GO:0005634//nucleus,GO:0021521//ventral spinal cord interneuron specification;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding,-
1203,17,0,0,23,63,1,0,0,10,0,53,0,"CLN5;ceroid-lipofuscinosis, neuronal 5",GO:0005775//vacuolar lumen;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005765//lysosomal membrane,GO:0007420//brain development;GO:0006465//signal peptide processing;GO:0007042//lysosomal lumen acidification;GO:0030163//protein catabolic process;GO:0042551//neuron maturation;GO:0007601//visual perception;GO:0008219//cell death;GO:0022008//neurogenesis;GO:0070085//glycosylation,GO:0005537//mannose binding;GO:0005515//protein binding,K12390//Lysosome
120376,0,131,21,38,103,0,0,98,34,0,27,0,COLCA2;colorectal cancer associated 2,GO:0005737//cytoplasm,-,-,-
120379,0,0,17,11,16,0,0,0,1,0,0,0,PIH1D2;PIH1 domain containing 2,-,-,-,-
120400,0,0,0,0,11,6,6,0,0,0,0,0,"NXPE1;neurexophilin and PC-esterase domain family, member 1",GO:0005576//extracellular region,-,-,-
120425,0,0,0,0,0,0,1,0,28,0,0,0,"AMICA1;adhesion molecule, interacts with CXADR antigen 1",GO:0016021//integral component of membrane;GO:0005923//tight junction;GO:0005886//plasma membrane,GO:0050900//leukocyte migration;GO:0072672//neutrophil extravasation;GO:0035696//monocyte extravasation;GO:0050776//regulation of immune response;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0046629//gamma-delta T cell activation;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0007596//blood coagulation;GO:0030593//neutrophil chemotaxis,GO:0005178//integrin binding;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding,K06770//Cell adhesion molecules (CAMs)
120526,1,49,14,124,130,1,20,0,35,77,56,0,"DNAJC24;DnaJ (Hsp40) homolog, subfamily C, member 24",GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process;GO:0032781//positive regulation of ATPase activity;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0061077//chaperone-mediated protein folding,GO:0001671//ATPase activator activity;GO:0008198//ferrous iron binding;GO:0008270//zinc ion binding,K11447//Transcriptional misregulation in cancer
120534,0,0,0,11,8,0,0,0,0,0,0,0,ARL14EP;ADP-ribosylation factor-like 14 effector protein,GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
120586,0,0,0,0,0,0,0,0,14,0,0,0,"OR8I2;olfactory receptor, family 8, subfamily I, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1207,144,52,0,20,45,0,2,0,9,0,0,0,"CLNS1A;chloride channel, nucleotide-sensitive, 1A",GO:0005634//nucleus;GO:0034709//methylosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0034715//pICln-Sm protein complex,GO:0010467//gene expression;GO:0006884//cell volume homeostasis;GO:0006821//chloride transport;GO:0016070//RNA metabolic process;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K05019//RNA transport
120775,0,0,0,0,0,11,0,0,2,0,0,0,"OR2D3;olfactory receptor, family 2, subfamily D, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
120776,0,0,0,0,0,0,28,0,0,0,0,0,"OR2D2;olfactory receptor, family 2, subfamily D, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
120787,0,0,0,0,0,0,0,0,0,0,14,0,"OR52W1;olfactory receptor, family 52, subfamily W, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
120793,0,0,0,0,0,0,0,2,15,0,0,0,"OR56A4;olfactory receptor, family 56, subfamily A, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
120796,0,0,0,0,0,0,0,0,19,0,0,0,"OR56A1;olfactory receptor, family 56, subfamily A, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
1208,0,0,0,0,0,0,0,0,10,0,0,0,"CLPS;colipase, pancreatic",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0044241//lipid digestion;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0007603//phototransduction, visible light;GO:0043085//positive regulation of catalytic activity",GO:0008047//enzyme activator activity,K14460//Fat digestion and absorption
120863,0,0,0,0,0,0,0,0,0,0,8,0,DEPDC4;DEP domain containing 4,-,GO:0035556//intracellular signal transduction,-,-
120892,0,0,0,12,0,14,5,0,35,0,1,0,LRRK2;leucine-rich repeat kinase 2,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0043195//terminal bouton;GO:0045121//membrane raft;GO:0016234//inclusion body;GO:0005783//endoplasmic reticulum;GO:0032839//dendrite cytoplasm;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0043025//neuronal cell body;GO:0005615//extracellular space;GO:0031966//mitochondrial membrane;GO:0030424//axon;GO:0043204//perikaryon;GO:0005764//lysosome;GO:0008021//synaptic vesicle;GO:0043005//neuron projection;GO:0005768//endosome;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,"GO:0061001//regulation of dendritic spine morphogenesis;GO:0000186//activation of MAPKK activity;GO:0032092//positive regulation of protein binding;GO:0001933//negative regulation of protein phosphorylation;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0032091//negative regulation of protein binding;GO:1901214//regulation of neuron death;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0007264//small GTPase mediated signal transduction;GO:0051900//regulation of mitochondrial depolarization;GO:0072593//reactive oxygen species metabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043547//positive regulation of GTPase activity;GO:0035641//locomotory exploration behavior;GO:0043068//positive regulation of programmed cell death;GO:0006914//autophagy;GO:0006897//endocytosis;GO:0018107//peptidyl-threonine phosphorylation;GO:0001934//positive regulation of protein phosphorylation;GO:0035640//exploration behavior;GO:0006979//response to oxidative stress;GO:0034599//cellular response to oxidative stress;GO:0031398//positive regulation of protein ubiquitination;GO:0040012//regulation of locomotion;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0071287//cellular response to manganese ion;GO:0048312//intracellular distribution of mitochondria;GO:0034260//negative regulation of GTPase activity;GO:0000165//MAPK cascade;GO:0006184//GTP catabolic process;GO:0000187//activation of MAPK activity;GO:0042391//regulation of membrane potential;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0007528//neuromuscular junction development;GO:0048812//neuron projection morphogenesis;GO:0010508//positive regulation of autophagy;GO:0043406//positive regulation of MAP kinase activity;GO:0034613//cellular protein localization;GO:0021772//olfactory bulb development;GO:0008340//determination of adult lifespan;GO:0006468//protein phosphorylation;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000172//regulation of branching morphogenesis of a nerve;GO:0010738//regulation of protein kinase A signaling;GO:0010955//negative regulation of protein processing;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0070997//neuron death;GO:0051966//regulation of synaptic transmission, glutamatergic",GO:0030276//clathrin binding;GO:0004708//MAP kinase kinase activity;GO:0003924//GTPase activity;GO:0042803//protein homodimerization activity;GO:0044325//ion channel binding;GO:0004674//protein serine/threonine kinase activity;GO:0001948//glycoprotein binding;GO:0016301//kinase activity;GO:0005525//GTP binding;GO:0003779//actin binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0017048//Rho GTPase binding;GO:0004672//protein kinase activity;GO:0017075//syntaxin-1 binding;GO:0005096//GTPase activator activity;GO:0015631//tubulin binding;GO:0051018//protein kinase A binding;GO:0005515//protein binding;GO:0000149//SNARE binding,K08844//Parkinson's disease
1209,65,0,0,0,5,0,17,27,27,1,0,289,CLPTM1;cleft lip and palate associated transmembrane protein 1,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0009897//external side of plasma membrane,GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0033081//regulation of T cell differentiation in thymus,GO:0005515//protein binding,-
120935,0,0,0,0,1,0,0,0,18,0,3,0,CCDC38;coiled-coil domain containing 38,-,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K01468//Nicotinate and nicotinamide metabolism;Metabolic pathways;Histidine metabolism
120939,0,0,0,0,0,0,0,0,40,0,0,0,TMEM52B;transmembrane protein 52B,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K09254//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway
121006,0,0,0,0,0,20,43,0,61,0,0,0,"FAM186A;family with sequence similarity 186, member A",-,-,-,K06237//Small cell lung cancer;Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction;Pathways in cancer
121053,0,0,0,1,0,0,17,0,0,0,0,0,C12orf45;chromosome 12 open reading frame 45,-,-,-,-
1211,116,33,49,41,75,1,14,0,0,0,0,0,"CLTA;clathrin, light chain A",GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0071439//clathrin complex;GO:0016020//membrane;GO:0032588//trans-Golgi network membrane;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0030118//clathrin coat;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030132//clathrin coat of coated pit,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0061024//membrane organization;GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway,GO:0042277//peptide binding;GO:0005515//protein binding;GO:0032050//clathrin heavy chain binding;GO:0005198//structural molecule activity,K04644//Lysosome;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle;Bacterial invasion of epithelial cells;Endocytosis;Huntington's disease
121130,0,0,0,5,0,0,0,0,0,0,1,0,"OR10P1;olfactory receptor, family 10, subfamily P, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1212,0,0,0,0,0,0,3,0,13,0,0,0,"CLTB;clathrin, light chain B",GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0030118//clathrin coat;GO:0030132//clathrin coat of coated pit;GO:0060170//ciliary membrane;GO:0005802//trans-Golgi network,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0042277//peptide binding,K04645//Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle;Lysosome;Bacterial invasion of epithelial cells;Endocytosis;Huntington's disease
121214,0,0,0,0,21,0,0,0,0,0,0,0,"SDR9C7;short chain dehydrogenase/reductase family 9C, member 7",GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0055114//oxidation-reduction process,GO:0004745//retinol dehydrogenase activity,K11154//Retinol metabolism;Metabolic pathways
121227,46,0,0,4,0,26,0,0,1,0,0,0,LRIG3;leucine-rich repeats and immunoglobulin-like domains 3,GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0030659//cytoplasmic vesicle membrane;GO:0005886//plasma membrane,GO:0032474//otolith morphogenesis,-,K06850//Axon guidance
121256,0,0,0,0,1,69,0,0,45,20,0,0,TMEM132D;transmembrane protein 132D,GO:0016021//integral component of membrane,GO:0010923//negative regulation of phosphatase activity,GO:0005515//protein binding,-
121260,0,0,0,0,0,11,5,13,6,0,0,0,"SLC15A4;solute carrier family 15 (oligopeptide transporter), member 4",GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,GO:0015817//histidine transport;GO:0006811//ion transport;GO:0015031//protein transport;GO:0006857//oligopeptide transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity;GO:0005290//L-histidine transmembrane transporter activity,-
121268,0,0,0,0,0,25,0,0,21,0,0,0,RHEBL1;Ras homolog enriched in brain like 1,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031929//TOR signaling;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005525//GTP binding,-
121273,0,0,0,0,0,0,37,0,0,0,2,0,C12orf54;chromosome 12 open reading frame 54,-,-,-,-
121274,156,17,1,14,46,0,1,38,0,207,0,0,ZNF641;zinc finger protein 641,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
121278,0,0,0,0,0,0,0,0,0,0,1,0,TPH2;tryptophan hydroxylase 2,GO:0043005//neuron projection;GO:0005829//cytosol,GO:0009072//aromatic amino acid family metabolic process;GO:0046219//indolalkylamine biosynthetic process;GO:0051384//response to glucocorticoid;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0042427//serotonin biosynthetic process;GO:0031667//response to nutrient levels;GO:0034641//cellular nitrogen compound metabolic process;GO:0051592//response to calcium ion;GO:0071285//cellular response to lithium ion;GO:0014823//response to activity;GO:0043627//response to estrogen;GO:0007623//circadian rhythm,GO:0005506//iron ion binding;GO:0004510//tryptophan 5-monooxygenase activity;GO:0016597//amino acid binding,K00502//Metabolic pathways;Serotonergic synapse;Tryptophan metabolism
1213,0,242,3,436,1405,0,18,0,95,0,45,0,"CLTC;clathrin, heavy chain (Hc)",GO:0070062//extracellular vesicular exosome;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0071439//clathrin complex;GO:0016020//membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005925//focal adhesion;GO:0030118//clathrin coat;GO:0031982//vesicle;GO:0043234//protein complex;GO:0005819//spindle;GO:0005886//plasma membrane;GO:0042470//melanosome;GO:0030136//clathrin-coated vesicle;GO:0030132//clathrin coat of coated pit;GO:0032588//trans-Golgi network membrane;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0001649//osteoblast differentiation;GO:0033572//transferrin transport;GO:0031623//receptor internalization;GO:0006886//intracellular protein transport;GO:0007067//mitotic nuclear division;GO:0006898//receptor-mediated endocytosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006892//post-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:1900126//negative regulation of hyaluronan biosynthetic process,GO:0019901//protein kinase binding;GO:0005198//structural molecule activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0032051//clathrin light chain binding;GO:0003725//double-stranded RNA binding,K04646//Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle;Lysosome;Huntington's disease;Bacterial invasion of epithelial cells;Endocytosis
121355,0,0,0,0,0,0,0,48,0,1,0,0,GTSF1;gametocyte specific factor 1,GO:0005737//cytoplasm,-,GO:0046872//metal ion binding,K02728//Proteasome
121364,0,0,0,0,0,16,0,0,12,0,0,0,"OR10A7;olfactory receptor, family 10, subfamily A, member 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
121391,0,0,0,0,0,20,0,26,0,0,0,0,KRT74;keratin 74,GO:0005737//cytoplasm;GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,GO:0045104//intermediate filament cytoskeleton organization,GO:0005198//structural molecule activity;GO:1990254//keratin filament binding,-
121441,46,0,0,8,55,0,0,83,24,0,0,0,"NEDD1;neural precursor cell expressed, developmentally down-regulated 1",GO:0045177//apical part of cell;GO:0000922//spindle pole;GO:0005813//centrosome;GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005829//cytosol;GO:0000242//pericentriolar material,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division,-,K14549//Ribosome biogenesis in eukaryotes
121456,0,0,1,0,20,17,0,0,42,0,7,0,"SLC9A7P1;solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 pseudogene 1",-,-,-,K12041//Cardiac muscle contraction
121457,0,0,0,0,0,24,3,0,16,0,0,0,IKBIP;IKBKB interacting protein,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0010165//response to X-ray,GO:0005515//protein binding,K09291//RNA transport;Thyroid cancer;MAPK signaling pathway - yeast;Pathways in cancer;K11447//Transcriptional misregulation in cancer;K10062//Phagosome;K12478//Phagosome;Endocytosis;Tuberculosis
1215,35,0,0,0,75,0,0,0,0,0,0,0,"CMA1;chymase 1, mast cell",GO:0005622//intracellular;GO:0005576//extracellular region;GO:0031012//extracellular matrix,GO:0045766//positive regulation of angiogenesis;GO:0050720//interleukin-1 beta biosynthetic process;GO:0030901//midbrain development;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0071333//cellular response to glucose stimulus;GO:0044267//cellular protein metabolic process;GO:0002003//angiotensin maturation;GO:0006518//peptide metabolic process;GO:0050727//regulation of inflammatory response,GO:0042277//peptide binding;GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,K01329//Renin-angiotensin system
121504,0,0,0,0,0,0,0,0,6,0,0,0,"HIST4H4;histone cluster 4, H4",-,-,-,K11254//Alcoholism;Systemic lupus erythematosus
121512,94,19,0,32,149,20,37,0,41,0,10,0,"FGD4;FYVE, RhoGEF and PH domain containing 4",GO:0030175//filopodium;GO:0005794//Golgi apparatus;GO:0015629//actin cytoskeleton;GO:0001726//ruffle;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0030032//lamellipodium assembly;GO:0007010//cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0046847//filopodium assembly;GO:0030035//microspike assembly;GO:0043547//positive regulation of GTPase activity;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043088//regulation of Cdc42 GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0031267//small GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0003779//actin binding;GO:0005085//guanyl-nucleotide exchange factor activity,-
121536,0,9,0,22,40,20,0,0,35,1,0,0,AEBP2;AE binding protein 2,GO:0035098//ESC/E(Z) complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K06230//Hedgehog signaling pathway;Pathways in cancer;Basal cell carcinoma
121549,0,0,0,0,0,20,0,0,0,0,0,0,ASCL4;achaete-scute family bHLH transcription factor 4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0043588//skin development;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
121551,28,41,23,38,49,47,0,242,58,0,68,0,BTBD11;BTB (POZ) domain containing 11,GO:0016021//integral component of membrane,-,GO:0046982//protein heterodimerization activity,-
121601,0,0,0,13,0,0,43,0,39,0,14,0,ANO4;anoctamin 4,GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006821//chloride transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport,GO:0005229//intracellular calcium activated chloride channel activity,-
121642,0,1,0,10,0,26,8,0,12,0,0,0,"ALKBH2;alkB, alkylation repair homolog 2 (E. coli)",GO:0005654//nucleoplasm,GO:0006281//DNA repair;GO:0080111//DNA demethylation;GO:0035511//oxidative DNA demethylation;GO:0006307//DNA dealkylation involved in DNA repair;GO:0070989//oxidative demethylation,GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0008198//ferrous iron binding;GO:0051747//cytosine C-5 DNA demethylase activity,-
121643,0,0,0,0,0,14,0,0,10,4,16,0,FOXN4;forkhead box N4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0036302//atrioventricular canal development;GO:0001947//heart looping;GO:0008016//regulation of heart contraction;GO:0035881//amacrine cell differentiation;GO:0010842//retina layer formation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001158//enhancer sequence-specific DNA binding;GO:0003682//chromatin binding,-
121665,0,0,0,0,0,0,0,0,10,175,0,0,SPPL3;signal peptide peptidase like 3,GO:0005791//rough endoplasmic reticulum;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane,GO:0006509//membrane protein ectodomain proteolysis,"GO:0042803//protein homodimerization activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving",-
121793,0,0,0,0,0,0,0,0,15,0,0,0,TEX29;testis expressed 29,GO:0016021//integral component of membrane,-,-,-
121952,0,0,0,0,0,0,0,0,25,0,0,0,"METTL21EP;methyltransferase like 21E, pseudogene",-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
122011,0,0,27,0,0,0,18,0,19,0,0,0,"CSNK1A1L;casein kinase 1, alpha 1-like",GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex,GO:0000902//cell morphogenesis;GO:0006468//protein phosphorylation;GO:0016055//Wnt signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K08957//Wnt signaling pathway;Hedgehog signaling pathway
122042,0,0,0,0,0,47,0,0,54,0,6,0,RXFP2;relaxin/insulin-like family peptide receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008584//male gonad development;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0001556//oocyte maturation,GO:0017046//peptide hormone binding;GO:0016500//protein-hormone receptor activity,K04307//Neuroactive ligand-receptor interaction
122046,0,0,0,0,0,1,0,0,38,0,0,0,TEX26;testis expressed 26,-,-,-,-
122060,0,0,0,1,17,0,0,107,23,0,0,37,"SLAIN1;SLAIN motif family, member 1",-,-,-,-
122258,0,0,0,0,0,11,0,9,0,0,0,0,SPACA7;sperm acrosome associated 7,GO:0001669//acrosomal vesicle;GO:0005576//extracellular region,-,-,-
122402,105,0,0,0,0,22,54,61,39,0,6,0,TDRD9;tudor domain containing 9,GO:0005634//nucleus;GO:0071547//piP-body,GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0007275//multicellular organismal development;GO:0007140//male meiosis;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA,GO:0005524//ATP binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity,-
122416,0,0,0,0,0,0,0,0,25,0,8,267,ANKRD9;ankyrin repeat domain 9,-,-,-,-
122481,0,0,0,4,11,0,0,0,23,0,0,0,AK7;adenylate kinase 7,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0035082//axoneme assembly;GO:0003351//epithelial cilium movement;GO:0007283//spermatogenesis;GO:0007420//brain development;GO:0006165//nucleoside diphosphate phosphorylation;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0002437//inflammatory response to antigenic stimulus,GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0004017//adenylate kinase activity;GO:0004127//cytidylate kinase activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
122509,0,0,0,0,0,0,1,0,0,0,10,0,"IFI27L1;interferon, alpha-inducible protein 27-like 1",GO:0016021//integral component of membrane,-,-,-
122525,0,0,0,0,9,0,54,0,36,0,0,0,C14orf28;chromosome 14 open reading frame 28,-,-,-,-
122553,0,1,0,35,125,8,0,0,3,0,0,0,TRAPPC6B;trafficking protein particle complex 6B,GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,-
122616,0,0,0,0,0,0,0,0,0,0,3,0,C14orf79;chromosome 14 open reading frame 79,-,-,-,-
122618,0,0,0,0,0,0,18,0,17,0,0,0,"PLD4;phospholipase D family, member 4",GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0045335//phagocytic vesicle,GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006909//phagocytosis;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process,GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004630//phospholipase D activity,-
122622,44,0,0,1,11,0,0,0,47,0,9,3,ADSSL1;adenylosuccinate synthase like 1,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0014850//response to muscle activity;GO:0071257//cellular response to electrical stimulus;GO:0006184//GTP catabolic process;GO:0035690//cellular response to drug;GO:0042594//response to starvation;GO:0046040//IMP metabolic process;GO:0006541//glutamine metabolic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0006531//aspartate metabolic process;GO:0002376//immune system process;GO:0044281//small molecule metabolic process;GO:0006167//AMP biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process,GO:0005525//GTP binding;GO:0000287//magnesium ion binding;GO:0004019//adenylosuccinate synthase activity;GO:0003924//GTPase activity;GO:0051015//actin filament binding;GO:0042301//phosphate ion binding;GO:0042803//protein homodimerization activity,"K01939//Purine metabolism;Chloroalkane and chloroalkene degradation;Microbial metabolism in diverse environments;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Chlorocyclohexane and chlorobenzene degradation;Other glycan degradation"
122664,0,0,0,9,0,0,39,0,17,0,4,0,TPPP2;tubulin polymerization-promoting protein family member 2,GO:0005737//cytoplasm,-,-,-
122665,0,0,0,0,0,10,0,0,0,0,0,0,"RNASE8;ribonuclease, RNase A family, 8",GO:0005576//extracellular region,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0004522//pancreatic ribonuclease activity;GO:0003676//nucleic acid binding,-
122704,0,0,0,1,0,42,18,0,12,0,0,0,MRPL52;mitochondrial ribosomal protein L52,GO:0005762//mitochondrial large ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
122706,0,0,0,0,0,0,46,0,0,0,0,0,"PSMB11;proteasome (prosome, macropain) subunit, beta type, 11",GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0006915//apoptotic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process",GO:0004298//threonine-type endopeptidase activity,K11598//Proteasome
122740,0,0,0,0,0,0,0,0,2,0,0,0,"OR4K14;olfactory receptor, family 4, subfamily K, member 14",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
122748,56,0,0,0,0,0,9,0,13,0,0,0,"OR11H6;olfactory receptor, family 11, subfamily H, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
122769,186,0,0,0,9,5,0,0,4,0,58,0,LRR1;leucine rich repeat protein 1,-,GO:0016567//protein ubiquitination,-,-
122773,0,0,0,5,10,1,0,43,15,0,0,0,KLHDC1;kelch domain containing 1,GO:0005737//cytoplasm,-,-,K14966//Herpes simplex infection
122786,0,14,0,0,10,6,26,0,59,0,0,0,FRMD6;FERM domain containing 6,GO:0005886//plasma membrane;GO:0043296//apical junction complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0003383//apical constriction;GO:0032970//regulation of actin filament-based process;GO:0034613//cellular protein localization,-,-
122809,0,28,6,7,34,33,31,0,20,0,0,0,SOCS4;suppressor of cytokine signaling 4,-,GO:0040008//regulation of growth;GO:0035556//intracellular signal transduction;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination,-,K04697//Jak-STAT signaling pathway;Insulin signaling pathway;Type II diabetes mellitus
122830,0,3,1,13,27,0,20,0,40,0,0,0,"NAA30;N(alpha)-acetyltransferase 30, NatC catalytic subunit",GO:0005844//polysome;GO:0031417//NatC complex;GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0005515//protein binding,-
122945,0,0,0,5,18,0,0,1,17,0,15,0,NOXRED1;NADP-dependent oxidoreductase domain containing 1,-,GO:0006561//proline biosynthetic process;GO:0055114//oxidation-reduction process,GO:0004735//pyrroline-5-carboxylate reductase activity,"K00286//Arginine and proline metabolism;Metabolic pathways;Pyruvate metabolism;Propanoate metabolism;Two-component system;Glycine, serine and threonine metabolism;Methane metabolism;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments"
122953,0,0,0,0,0,0,56,0,40,200,0,0,JDP2;Jun dimerization protein 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045599//negative regulation of fat cell differentiation;GO:0031065//positive regulation of histone deacetylation",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding;GO:0003682//chromatin binding,-
122961,63,2,0,0,22,0,0,0,33,0,8,0,ISCA2;iron-sulfur cluster assembly 2,GO:0005739//mitochondrion,GO:0016226//iron-sulfur cluster assembly,GO:0046872//metal ion binding;GO:0005198//structural molecule activity;GO:0051536//iron-sulfur cluster binding,-
122970,1,0,0,0,0,0,0,0,0,0,0,0,ACOT4;acyl-CoA thioesterase 4,GO:0005777//peroxisome,GO:0001676//long-chain fatty acid metabolic process;GO:0043649//dicarboxylic acid catabolic process;GO:0006637//acyl-CoA metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0046459//short-chain fatty acid metabolic process;GO:0032789//unsaturated monocarboxylic acid metabolic process;GO:0032788//saturated monocarboxylic acid metabolic process;GO:0019605//butyrate metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0006104//succinyl-CoA metabolic process,GO:0016290//palmitoyl-CoA hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0005102//receptor binding;GO:0004778//succinyl-CoA hydrolase activity,K01068//Fatty acid elongation;Biosynthesis of secondary metabolites;Biosynthesis of unsaturated fatty acids
123,0,1,0,0,10,0,0,0,21,0,0,0,PLIN2;perilipin 2,GO:0005829//cytosol;GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005634//nucleus,GO:0044281//small molecule metabolic process;GO:0019915//lipid storage;GO:0044255//cellular lipid metabolic process;GO:0015909//long-chain fatty acid transport;GO:0014070//response to organic cyclic compound;GO:0042493//response to drug,-,K08768//PPAR signaling pathway
1230,0,0,0,0,0,9,0,0,19,12,0,0,CCR1;chemokine (C-C motif) receptor 1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,"GO:0019221//cytokine-mediated signaling pathway;GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006935//chemotaxis;GO:0006887//exocytosis;GO:0009611//response to wounding;GO:0006954//inflammatory response;GO:0002407//dendritic cell chemotaxis;GO:0008152//metabolic process;GO:0006816//calcium ion transport;GO:0045672//positive regulation of osteoclast differentiation;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051928//positive regulation of calcium ion transport;GO:0090026//positive regulation of monocyte chemotaxis;GO:0006955//immune response;GO:0006874//cellular calcium ion homeostasis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0010629//negative regulation of gene expression;GO:0030502//negative regulation of bone mineralization",GO:0019957//C-C chemokine binding;GO:0016493//C-C chemokine receptor activity;GO:0071791//chemokine (C-C motif) ligand 5 binding;GO:0004950//chemokine receptor activity;GO:0035717//chemokine (C-C motif) ligand 7 binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding,K04176//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
123016,89,7,0,18,42,2,0,0,59,0,10,0,TTC8;tetratricopeptide repeat domain 8,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0032391//photoreceptor connecting cilium;GO:0034464//BBSome;GO:0036064//ciliary basal body;GO:0005929//cilium,GO:0035264//multicellular organism growth;GO:0021772//olfactory bulb development;GO:0007608//sensory perception of smell;GO:0048560//establishment of anatomical structure orientation;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0007411//axon guidance;GO:0042384//cilium assembly;GO:0061326//renal tubule development;GO:0015031//protein transport;GO:0032880//regulation of protein localization;GO:0045444//fat cell differentiation;GO:0050893//sensory processing;GO:0035058//nonmotile primary cilium assembly,GO:0005515//protein binding;GO:0001103//RNA polymerase II repressing transcription factor binding,-
123036,0,84,2,158,411,13,0,209,19,0,0,0,"TC2N;tandem C2 domains, nuclear",GO:0005634//nucleus,GO:0030193//regulation of blood coagulation;GO:0010468//regulation of gene expression,-,K15290//Synaptic vesicle cycle
123041,0,0,0,0,0,23,20,0,59,2,0,1,"SLC24A4;solute carrier family 24 (sodium/potassium/calcium exchanger), member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050896//response to stimulus;GO:0097186//amelogenesis;GO:0006874//cellular calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0006811//ion transport;GO:0007608//sensory perception of smell;GO:0006813//potassium ion transport,"GO:0015293//symporter activity;GO:0008273//calcium, potassium:sodium antiporter activity",-
123096,0,0,0,0,0,0,0,0,10,125,0,0,"SLC25A29;solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:1902616//acyl carnitine transmembrane transport,GO:0015227//acyl carnitine transmembrane transporter activity,-
123099,0,0,0,0,0,7,17,0,36,0,0,0,"DEGS2;delta(4)-desaturase, sphingolipid 2",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0046513//ceramide biosynthetic process;GO:0006667//sphinganine metabolic process;GO:0006665//sphingolipid metabolic process,GO:0042284//sphingolipid delta-4 desaturase activity;GO:0000170//sphingosine hydroxylase activity,K04712//Sphingolipid metabolism;Metabolic pathways
123103,0,0,0,0,0,13,0,0,11,0,0,0,KLHL33;kelch-like family member 33,-,-,-,-
123169,0,0,0,5,24,0,3,0,44,0,0,0,"LEO1;Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)",GO:0016593//Cdc73/Paf1 complex,"GO:0016055//Wnt signaling pathway;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation;GO:0006378//mRNA polyadenylation;GO:0019827//stem cell maintenance;GO:0001711//endodermal cell fate commitment;GO:0033523//histone H2B ubiquitination;GO:0006351//transcription, DNA-templated;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0010390//histone monoubiquitination",GO:0005515//protein binding,-
1232,0,0,0,0,0,0,0,0,0,0,1,0,CCR3;chemokine (C-C motif) receptor 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0006954//inflammatory response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016032//viral process;GO:0007155//cell adhesion;GO:0001938//positive regulation of endothelial cell proliferation;GO:0070098//chemokine-mediated signaling pathway;GO:0006968//cellular defense response;GO:0006935//chemotaxis,GO:0005515//protein binding;GO:0004950//chemokine receptor activity;GO:0016493//C-C chemokine receptor activity,K04178//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
123207,0,287,2,241,483,0,1,0,11,0,338,720,C15orf40;chromosome 15 open reading frame 40,-,-,-,-
123228,0,0,47,0,0,0,0,3,18,0,0,0,SENP8;SUMO/sentrin specific peptidase family member 8,-,GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity,-
123263,0,28,0,0,1,0,13,0,53,0,0,0,MTFMT;mitochondrial methionyl-tRNA formyltransferase,GO:0005739//mitochondrion,GO:0006413//translational initiation;GO:0071951//conversion of methionyl-tRNA to N-formyl-methionyl-tRNA,GO:0004479//methionyl-tRNA formyltransferase activity,K00604//Aminoacyl-tRNA biosynthesis;One carbon pool by folate
123264,64,0,0,0,0,0,0,0,0,0,0,0,"SLC51B;solute carrier family 51, beta subunit",GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0060050//positive regulation of protein glycosylation;GO:0090314//positive regulation of protein targeting to membrane;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0015721//bile acid and bile salt transport;GO:0031647//regulation of protein stability,GO:0005215//transporter activity;GO:0046982//protein heterodimerization activity,K14361//Bile secretion
123283,0,0,0,0,2,70,6,0,75,24,12,0,TARSL2;threonyl-tRNA synthetase-like 2,GO:0005737//cytoplasm,GO:0006435//threonyl-tRNA aminoacylation,GO:0005524//ATP binding;GO:0004829//threonine-tRNA ligase activity,K01868//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Vitamin B6 metabolism
123346,0,0,0,0,0,0,0,0,8,0,0,0,"HIGD2B;HIG1 hypoxia inducible domain family, member 2B",GO:0016021//integral component of membrane,-,-,-
123355,0,0,0,0,1,0,0,0,1,0,2,0,LRRC28;leucine rich repeat containing 28,-,-,-,K01768//Purine metabolism;Meiosis - yeast;K12796//NOD-like receptor signaling pathway
1234,0,0,23,0,0,19,0,19,3,0,7,0,CCR5;chemokine (C-C motif) receptor 5 (gene/pseudogene),GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface,GO:0006968//cellular defense response;GO:0006935//chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0030260//entry into host cell;GO:0071222//cellular response to lipopolysaccharide;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0019722//calcium-mediated signaling;GO:0070723//response to cholesterol;GO:0002407//dendritic cell chemotaxis;GO:0016032//viral process;GO:0006954//inflammatory response;GO:0006816//calcium ion transport;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0000165//MAPK cascade;GO:0007267//cell-cell signaling;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0015026//coreceptor activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0003779//actin binding;GO:0019957//C-C chemokine binding;GO:0016493//C-C chemokine receptor activity;GO:0071791//chemokine (C-C motif) ligand 5 binding;GO:0004950//chemokine receptor activity,K04180//Chemokine signaling pathway;Toxoplasmosis;Endocytosis;Cytokine-cytokine receptor interaction
1235,0,0,0,0,0,13,0,0,17,0,0,0,CCR6;chemokine (C-C motif) receptor 6,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006959//humoral immune response;GO:0070098//chemokine-mediated signaling pathway;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006928//cellular component movement;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045087//innate immune response;GO:0002407//dendritic cell chemotaxis;GO:0007165//signal transduction,GO:0004950//chemokine receptor activity;GO:0004872//receptor activity;GO:0016493//C-C chemokine receptor activity,K04181//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
123591,139,0,0,0,0,27,0,0,58,0,4,117,C15orf27;chromosome 15 open reading frame 27,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0070588//calcium ion transmembrane transport;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import,GO:0005245//voltage-gated calcium channel activity,K03522//Sulfur relay system;Nitrogen metabolism
123606,20,2,0,1,38,0,55,0,31,1,0,593,NIPA1;non imprinted in Prader-Willi/Angelman syndrome 1,GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0008219//cell death;GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
123624,196,0,0,0,10,19,37,0,84,0,0,0,AGBL1;ATP/GTP binding protein-like 1,GO:0005829//cytosol,GO:0035609//C-terminal protein deglutamylation;GO:0006508//proteolysis;GO:0035610//protein side chain deglutamylation,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0015631//tubulin binding,-
123688,0,0,0,0,0,0,0,0,11,0,0,0,HYKK;hydroxylysine kinase,GO:0005737//cytoplasm,GO:0016310//phosphorylation,GO:0047992//hydroxylysine kinase activity,-
1237,0,0,24,0,0,0,0,0,0,0,1,0,CCR8;chemokine (C-C motif) receptor 8,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070098//chemokine-mediated signaling pathway;GO:0006935//chemotaxis;GO:0006955//immune response,GO:0004950//chemokine receptor activity;GO:0015026//coreceptor activity;GO:0016493//C-C chemokine receptor activity,K04183//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
123720,80,19,55,50,128,23,0,23,31,140,70,0,"WHAMM;WAS protein homolog associated with actin, golgi membranes and microtubules",GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0097320//membrane tubulation;GO:0007015//actin filament organization;GO:0030032//lamellipodium assembly;GO:0090527//actin filament reorganization;GO:0048041//focal adhesion assembly;GO:0051127//positive regulation of actin nucleation,GO:0008017//microtubule binding;GO:0017049//GTP-Rho binding;GO:0071933//Arp2/3 complex binding;GO:0003779//actin binding,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K11447//Transcriptional misregulation in cancer
123722,0,0,0,12,0,10,62,0,35,163,62,0,FSD2;fibronectin type III and SPRY domain containing 2,-,-,-,K08285//Ubiquitin mediated proteolysis
123745,0,0,0,0,0,9,0,0,41,40,0,0,"PLA2G4E;phospholipase A2, group IVE",GO:0005765//lysosomal membrane;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0009395//phospholipid catabolic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling,GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding,K01047//Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Glycerophospholipid metabolism;Ether lipid metabolism;VEGF signaling pathway;GnRH signaling pathway;Serotonergic synapse;Pancreatic secretion;alpha-Linolenic acid metabolism;Glutamatergic synapse;Linoleic acid metabolism;MAPK signaling pathway;Vascular smooth muscle contraction;Metabolic pathways
123775,0,0,0,0,0,0,37,0,8,0,0,0,C16orf46;chromosome 16 open reading frame 46,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,-,-,-
1238,21,0,0,0,0,0,27,0,24,0,0,0,ACKR2;atypical chemokine receptor 2,GO:0005887//integral component of plasma membrane;GO:0005884//actin filament;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0007275//multicellular organismal development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0042119//neutrophil activation;GO:0006898//receptor-mediated endocytosis;GO:0006954//inflammatory response,GO:0004950//chemokine receptor activity;GO:0016494//C-X-C chemokine receptor activity;GO:0016493//C-C chemokine receptor activity;GO:0005044//scavenger receptor activity;GO:0019957//C-C chemokine binding,-
123803,0,12,22,60,34,0,0,0,0,0,27,0,NTAN1;N-terminal asparagine amidase,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0007613//memory;GO:0008344//adult locomotory behavior,GO:0008418//protein-N-terminal asparagine amidohydrolase activity,-
123811,0,0,0,6,36,0,0,0,0,0,0,0,FOPNL;FGFR1OP N-terminal like,GO:0005634//nucleus;GO:0005813//centrosome;GO:0034451//centriolar satellite;GO:0031514//motile cilium;GO:0036064//ciliary basal body,GO:0042384//cilium assembly;GO:0034453//microtubule anchoring,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
123872,0,0,0,22,14,0,1,0,24,0,0,0,"DNAAF1;dynein, axonemal, assembly factor 1",GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0005634//nucleus;GO:0005886//plasma membrane,GO:0071907//determination of digestive tract left/right asymmetry;GO:0003356//regulation of cilium beat frequency;GO:0044458//motile cilium assembly;GO:0071910//determination of liver left/right asymmetry;GO:0003341//cilium movement;GO:0001947//heart looping;GO:0070286//axonemal dynein complex assembly;GO:0036159//inner dynein arm assembly;GO:0030324//lung development;GO:0060972//left/right pattern formation;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0035469//determination of pancreatic left/right asymmetry;GO:0036158//outer dynein arm assembly;GO:0060271//cilium morphogenesis,GO:0045502//dynein binding,-
123876,54,0,0,0,0,31,8,32,0,117,0,0,ACSM2A;acyl-CoA synthetase medium-chain family member 2A,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006631//fatty acid metabolic process;GO:0070328//triglyceride homeostasis;GO:0036112//medium-chain fatty-acyl-CoA metabolic process;GO:0042593//glucose homeostasis,GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
123879,0,0,0,0,12,0,0,0,9,0,0,0,"DCUN1D3;DCN1, defective in cullin neddylation 1, domain containing 3",GO:0048471//perinuclear region of cytoplasm,GO:0010225//response to UV-C;GO:0030308//negative regulation of cell growth;GO:0043065//positive regulation of apoptotic process;GO:0010332//response to gamma radiation,-,-
123920,4,0,0,0,0,0,0,0,9,0,7,0,CMTM3;CKLF-like MARVEL transmembrane domain containing 3,GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
123970,0,1,0,0,0,0,0,0,27,0,5,0,C16orf78;chromosome 16 open reading frame 78,GO:0005634//nucleus,-,-,-
124,0,0,0,0,22,0,27,94,22,0,0,0,"ADH1A;alcohol dehydrogenase 1A (class I), alpha polypeptide",GO:0005829//cytosol,GO:0006069//ethanol oxidation;GO:0006066//alcohol metabolic process;GO:0017144//drug metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,"GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0008270//zinc ion binding;GO:0005515//protein binding",K13951//Tyrosine metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Glycolysis / Gluconeogenesis;Fatty acid metabolism;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism
1240,197,0,0,0,0,43,0,0,5,0,14,2,CMKLR1;chemokine-like receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0050848//regulation of calcium-mediated signaling;GO:0001501//skeletal system development;GO:0070098//chemokine-mediated signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010759//positive regulation of macrophage chemotaxis;GO:0032695//negative regulation of interleukin-12 production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045600//positive regulation of fat cell differentiation,GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0004930//G-protein coupled receptor activity,-
124044,0,1,0,0,1,0,0,46,15,0,0,0,SPATA2L;spermatogenesis associated 2-like,-,-,-,-
124045,0,0,0,0,0,0,7,0,20,0,23,0,SPATA33;spermatogenesis associated 33,GO:0005829//cytosol;GO:0005634//nucleus,-,-,K06236//Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
124056,0,0,0,7,0,0,0,244,14,0,23,0,NOXO1;NADPH oxidase organizer 1,GO:0043020//NADPH oxidase complex,GO:0006801//superoxide metabolic process;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0022617//extracellular matrix disassembly;GO:0060263//regulation of respiratory burst;GO:0043085//positive regulation of catalytic activity,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005543//phospholipid binding;GO:0019899//enzyme binding;GO:0016176//superoxide-generating NADPH oxidase activator activity,K08011//Osteoclast differentiation;Leishmaniasis;Chemokine signaling pathway;Phagosome;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration
124093,0,1,0,14,9,0,0,0,0,0,13,0,CCDC78;coiled-coil domain containing 78,GO:0016529//sarcoplasmic reticulum;GO:0098536//deuterosome;GO:0042383//sarcolemma;GO:0005814//centriole;GO:0048471//perinuclear region of cytoplasm,GO:0098535//de novo centriole assembly;GO:0030030//cell projection organization;GO:0003009//skeletal muscle contraction,-,-
1241,99,0,0,0,0,0,0,44,44,4,0,0,LTB4R;leukotriene B4 receptor,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006928//cellular component movement;GO:0006936//muscle contraction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0006954//inflammatory response,GO:0004974//leukotriene receptor activity;GO:0000166//nucleotide binding;GO:0001632//leukotriene B4 receptor activity,K04296//Neuroactive ligand-receptor interaction
124149,68,0,18,0,0,0,67,0,10,0,0,0,ANKRD26P1;ankyrin repeat domain 26 pseudogene 1,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
124152,0,1,0,15,31,0,14,64,2,0,0,0,IQCK;IQ motif containing K,-,-,-,-
124220,0,0,0,15,53,0,0,0,0,0,0,0,ZG16B;zymogen granule protein 16B,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0001895//retina homeostasis,GO:0030246//carbohydrate binding,-
124221,0,0,0,80,0,0,15,0,12,0,1,0,"PRSS30P;protease, serine, 30, pseudogene",-,-,-,-
124222,0,0,17,8,0,0,0,154,24,0,33,0,PAQR4;progestin and adipoQ receptor family member IV,GO:0016021//integral component of membrane,-,GO:0004872//receptor activity,K06633//Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation
124245,0,12,0,4,13,0,0,174,33,0,10,0,ZC3H18;zinc finger CCCH-type containing 18,GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
124274,75,0,0,0,0,0,0,0,0,0,0,0,GPR139;G protein-coupled receptor 139,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0046983//protein dimerization activity;GO:0008188//neuropeptide receptor activity,-
124359,0,32,0,7,100,0,1,1,23,0,0,0,"CDYL2;chromodomain protein, Y-like 2",GO:0005634//nucleus,GO:0008152//metabolic process,GO:0035064//methylated histone binding;GO:0005515//protein binding;GO:0003824//catalytic activity,K13239//Fatty acid metabolism;Peroxisome
1244,5,0,0,0,0,20,65,0,43,25,14,0,"ABCC2;ATP-binding cassette, sub-family C (CFTR/MRP), member 2",GO:0005886//plasma membrane;GO:0046581//intercellular canaliculus;GO:0009986//cell surface;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0043627//response to estrogen;GO:0070327//thyroid hormone transport;GO:0006979//response to oxidative stress;GO:0046685//response to arsenic-containing substance;GO:0015732//prostaglandin transport;GO:0055085//transmembrane transport;GO:0009408//response to heat;GO:0006855//drug transmembrane transport;GO:0006810//transport;GO:0006200//ATP catabolic process;GO:0031427//response to methotrexate;GO:0030644//cellular chloride ion homeostasis,"GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008514//organic anion transmembrane transporter activity;GO:0005515//protein binding",K05666//ABC transporters;Bile secretion
124401,0,0,2,0,21,0,2,125,96,0,10,0,ANKS3;ankyrin repeat and sterile alpha motif domain containing 3,-,-,-,-
124402,72,0,0,0,0,0,0,64,0,0,0,0,UBALD1;UBA-like domain containing 1,-,-,-,-
124411,0,0,0,13,5,0,0,0,23,0,7,0,ZNF720;zinc finger protein 720,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,-
124446,0,31,1,1,8,0,0,0,0,0,8,0,TMEM219;transmembrane protein 219,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006915//apoptotic process,-,-
124454,0,0,0,0,48,1,19,0,62,0,0,0,"EARS2;glutamyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006424//glutamyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0070127//tRNA aminoacylation for mitochondrial protein translation,GO:0050561//glutamate-tRNA(Gln) ligase activity;GO:0004818//glutamate-tRNA ligase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding,K01885//Biosynthesis of secondary metabolites;Aminobenzoate degradation;Porphyrin and chlorophyll metabolism;Microbial metabolism in diverse environments;Riboflavin metabolism;Two-component system;Metabolic pathways;Aminoacyl-tRNA biosynthesis
124460,80,0,42,0,0,0,5,0,51,0,17,0,SNX20;sorting nexin 20,GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
124491,0,0,0,8,15,0,16,0,7,0,0,0,TMEM170A;transmembrane protein 170A,GO:0016021//integral component of membrane,-,-,-
124512,0,2,0,0,0,0,21,32,33,0,0,332,METTL23;methyltransferase like 23,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0032259//methylation,GO:0008168//methyltransferase activity,K00884//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
124535,0,0,0,0,0,0,24,0,43,0,14,0,HSF5;heat shock transcription factor family member 5,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
124538,0,0,0,0,0,0,0,0,1,0,0,0,"OR4D2;olfactory receptor, family 4, subfamily D, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
124540,0,0,1,12,47,0,0,0,6,0,1,342,MSI2;musashi RNA-binding protein 2,GO:0005844//polysome;GO:0005737//cytoplasm,-,GO:0008266//poly(U) RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K14411//mRNA surveillance pathway
124565,38,0,0,0,2,57,69,0,35,42,0,0,"SLC38A10;solute carrier family 38, member 10",GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0060348//bone development;GO:0006865//amino acid transport;GO:0006814//sodium ion transport,-,-
124583,0,0,0,0,28,32,0,0,11,0,0,0,CANT1;calcium activated nucleotidase 1,GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane,GO:0030166//proteoglycan biosynthetic process;GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045134//uridine-diphosphatase activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity,K12304//Purine metabolism;Pyrimidine metabolism
124590,7,0,0,0,0,0,0,0,1,0,0,0,USH1G;Usher syndrome 1G (autosomal recessive),GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0042472//inner ear morphogenesis;GO:0050957//equilibrioception;GO:0007605//sensory perception of sound;GO:0045494//photoreceptor cell maintenance;GO:0060113//inner ear receptor cell differentiation;GO:0050953//sensory perception of light stimulus,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0030507//spectrin binding,K12460//Neurotrophin signaling pathway
124599,0,0,0,0,0,0,0,95,0,0,0,0,CD300LB;CD300 molecule-like family member b,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0002446//neutrophil mediated immunity;GO:0071222//cellular response to lipopolysaccharide;GO:0033005//positive regulation of mast cell activation;GO:0045087//innate immune response,-,-
124602,0,0,0,0,0,0,6,103,77,120,13,1,KIF19;kinesin family member 19,GO:0005929//cilium;GO:0005871//kinesin complex;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0070462//plus-end specific microtubule depolymerization;GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0060404//axonemal microtubule depolymerization,GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATPase activity,-
124626,0,0,0,0,0,0,0,0,5,0,0,0,ZPBP2;zona pellucida binding protein 2,GO:0001669//acrosomal vesicle;GO:0002199//zona pellucida receptor complex;GO:0005576//extracellular region;GO:0044297//cell body;GO:0005634//nucleus,GO:0001675//acrosome assembly;GO:0007339//binding of sperm to zona pellucida,-,-
124637,0,29,36,26,9,0,0,0,12,0,11,0,CYB5D1;cytochrome b5 domain containing 1,-,-,GO:0046872//metal ion binding;GO:0020037//heme binding,-
124641,0,0,0,0,0,20,0,0,2,0,0,0,OVCA2;ovarian tumor suppressor candidate 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0032526//response to retinoic acid,GO:0016787//hydrolase activity,-
124739,0,10,0,8,76,0,7,87,40,0,27,0,USP43;ubiquitin specific peptidase 43,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
124751,0,0,0,0,8,10,31,0,0,0,0,0,KRBA2;KRAB-A domain containing 2,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated;GO:0015074//DNA integration",GO:0003676//nucleic acid binding,K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
124773,56,0,0,0,0,0,0,0,16,0,0,0,C17orf64;chromosome 17 open reading frame 64,-,-,-,-
124783,114,34,0,0,60,0,0,112,19,0,0,1,SPATA32;spermatogenesis associated 32,GO:0048471//perinuclear region of cytoplasm,GO:0007283//spermatogenesis,GO:0003779//actin binding,-
124790,0,1,0,19,49,0,0,24,0,0,19,0,HEXIM2;hexamethylene bis-acetamide inducible 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0017069//snRNA binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0005515//protein binding,-
124801,0,0,0,0,51,5,17,0,42,0,2,0,LSM12;LSM12 homolog (S. cerevisiae),-,-,-,-
124808,0,67,86,27,89,0,0,59,21,0,0,0,CCDC43;coiled-coil domain containing 43,-,-,-,-
124817,0,315,123,484,771,30,37,0,45,17,661,0,CNTD1;cyclin N-terminal domain containing 1,-,-,-,K08334//Regulation of autophagy
124857,13,0,1,0,0,0,16,0,53,0,0,0,"WFIKKN2;WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2",GO:0005576//extracellular region,GO:0048747//muscle fiber development;GO:0001501//skeletal system development;GO:0010951//negative regulation of endopeptidase activity;GO:0043392//negative regulation of DNA binding;GO:0060021//palate development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0032091//negative regulation of protein binding,GO:0008191//metalloendopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades
124871,0,0,0,0,0,0,0,0,20,0,0,0,FLJ40194;uncharacterized FLJ40194,-,-,-,-
124872,0,0,0,0,0,0,0,0,16,0,0,0,"B4GALNT2;beta-1,4-N-acetyl-galactosaminyl transferase 2",GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane,GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0022408//negative regulation of cell-cell adhesion;GO:0019276//UDP-N-acetylgalactosamine metabolic process;GO:0030259//lipid glycosylation;GO:0006486//protein glycosylation,GO:0008376//acetylgalactosaminyltransferase activity,-
124923,0,0,0,0,0,3,0,0,0,0,0,0,SGK494;uncharacterized serine/threonine-protein kinase SgK494,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04345//Long-term potentiation;Progesterone-mediated oocyte maturation;Insulin signaling pathway;Amoebiasis;Amphetamine addiction;Glutamatergic synapse;Taste transduction;Wnt signaling pathway;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Dilated cardiomyopathy;Salivary secretion;GABAergic synapse;Cholinergic synapse;Vibrio cholerae infection;Melanogenesis;Serotonergic synapse;Alcoholism;Dopaminergic synapse;Cocaine addiction;Gap junction;Chemokine signaling pathway;GnRH signaling pathway;Meiosis - yeast;Epstein-Barr virus infection;MAPK signaling pathway;Hedgehog signaling pathway;Apoptosis;Morphine addiction;Oocyte meiosis;Endocrine and other factor-regulated calcium reabsorption;Olfactory transduction;Retrograde endocannabinoid signaling;Calcium signaling pathway;HTLV-I infection;Gastric acid secretion;Bile secretion;Prion diseases;K04373//Progesterone-mediated oocyte maturation;Long-term potentiation;MAPK signaling pathway;Neurotrophin signaling pathway;mTOR signaling pathway;Oocyte meiosis
124925,177,0,0,0,0,44,85,0,33,0,6,0,SEZ6;seizure related 6 homolog (mouse),GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0043198//dendritic shaft;GO:0005886//plasma membrane;GO:0097440//apical dendrite;GO:0043197//dendritic spine;GO:0043025//neuronal cell body;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm,GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0008344//adult locomotory behavior;GO:1900006//positive regulation of dendrite development;GO:0021680//cerebellar Purkinje cell layer development;GO:2000171//negative regulation of dendrite development;GO:0060074//synapse maturation;GO:0090036//regulation of protein kinase C signaling,-,K03993//Complement and coagulation cascades;Staphylococcus aureus infection;K04012//Hematopoietic cell lineage;Epstein-Barr virus infection;Complement and coagulation cascades;B cell receptor signaling pathway
124930,0,0,2,0,0,0,20,0,13,0,0,0,ANKRD13B;ankyrin repeat domain 13B,GO:0005770//late endosome;GO:0005769//early endosome;GO:0005886//plasma membrane,-,-,-
124935,0,1,0,0,0,10,49,1,27,167,18,0,"SLC43A2;solute carrier family 43 (amino acid system L transporter), member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006865//amino acid transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0006811//ion transport;GO:0055085//transmembrane transport,GO:0015179//L-amino acid transmembrane transporter activity,-
124936,0,0,54,0,0,14,0,0,17,0,0,0,CYB5D2;cytochrome b5 domain containing 2,GO:0005576//extracellular region,GO:0007399//nervous system development,GO:0020037//heme binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
124944,0,24,55,25,5,0,0,0,11,0,100,0,C17orf49;chromosome 17 open reading frame 49,GO:0016589//NURF complex;GO:0071339//MLL1 complex,GO:0016568//chromatin modification,GO:0003682//chromatin binding;GO:0003677//DNA binding,-
124961,0,0,0,0,21,4,41,0,34,85,18,0,ZFP3;ZFP3 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
124975,0,0,0,0,0,0,0,0,27,0,0,0,GGT6;gamma-glutamyltransferase 6,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0031362//anchored component of external side of plasma membrane,GO:0006749//glutathione metabolic process;GO:0006750//glutathione biosynthetic process;GO:0019370//leukotriene biosynthetic process;GO:0006508//proteolysis,GO:0003840//gamma-glutamyltransferase activity;GO:0036374//glutathione hydrolase activity,K00681//Glutathione metabolism;Taurine and hypotaurine metabolism;Cyanoamino acid metabolism;Arachidonic acid metabolism;Metabolic pathways
124976,57,44,18,34,98,19,0,99,132,1,179,0,SPNS2;spinster homolog 2 (Drosophila),GO:0016021//integral component of membrane,GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0002920//regulation of humoral immune response;GO:0043029//T cell homeostasis;GO:0048073//regulation of eye pigmentation;GO:0006665//sphingolipid metabolic process;GO:0048535//lymph node development;GO:0001782//B cell homeostasis;GO:0055085//transmembrane transport;GO:0072676//lymphocyte migration;GO:0060348//bone development;GO:0006869//lipid transport,GO:0046624//sphingolipid transporter activity,-
124989,0,0,0,0,0,0,0,0,56,0,0,0,EFCAB13;EF-hand calcium binding domain 13,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005509//calcium ion binding,K02183//Alcoholism;Pertussis;Tuberculosis;Long-term potentiation;GnRH signaling pathway;Phosphatidylinositol signaling system;Dopaminergic synapse;Insulin signaling pathway;Phototransduction;Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Vascular smooth muscle contraction;Oocyte meiosis;Calcium signaling pathway;Olfactory transduction;Salivary secretion;Gastric acid secretion;Glioma;Melanogenesis;Neurotrophin signaling pathway;Alzheimer's disease;K13448//Plant-pathogen interaction
124995,0,0,0,7,0,33,0,0,40,52,9,0,MRPL10;mitochondrial ribosomal protein L10,GO:0005762//mitochondrial large ribosomal subunit;GO:0030529//ribonucleoprotein complex;GO:0005739//mitochondrion,GO:0006412//translation;GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
124997,0,1,0,8,3,27,4,3,21,11,0,0,WDR81;WD repeat domain 81,-,GO:0008152//metabolic process;GO:0010923//negative regulation of phosphatase activity,"GO:0016772//transferase activity, transferring phosphorus-containing groups",-
125,0,44,0,0,4,11,0,0,0,0,0,0,"ADH1B;alcohol dehydrogenase 1B (class I), beta polypeptide",GO:0005829//cytosol,GO:0006069//ethanol oxidation;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,"GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0008270//zinc ion binding",K13951//Glycolysis / Gluconeogenesis;Fatty acid metabolism;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Tyrosine metabolism;Drug metabolism - cytochrome P450;Metabolic pathways
125058,147,66,2,42,78,45,64,23,43,8,33,0,"TBC1D16;TBC1 domain family, member 16",-,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
125061,0,23,1,16,28,10,0,55,17,0,0,0,AFMID;arylformamidase,GO:0005634//nucleus;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0034641//cellular nitrogen compound metabolic process;GO:0006569//tryptophan catabolic process;GO:0034354//'de novo' NAD biosynthetic process from tryptophan,GO:0004061//arylformamidase activity,K01432//Tryptophan metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways
125111,1,228,168,137,291,0,0,153,0,0,424,0,"GJD3;gap junction protein, delta 3, 31.9kDa",GO:0005887//integral component of plasma membrane;GO:0005922//connexon complex;GO:0009986//cell surface,GO:0007154//cell communication;GO:0016264//gap junction assembly;GO:0034220//ion transmembrane transport,GO:0005216//ion channel activity;GO:0005515//protein binding,-
125113,0,0,52,0,0,0,42,0,0,0,0,0,KRT222;keratin 222,GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
125115,0,0,0,0,0,27,0,0,0,0,0,0,KRT40;keratin 40,GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
125144,0,76,0,115,334,22,1,2,20,0,5,0,LRRC75A-AS1;LRRC75A antisense RNA 1,GO:0005739//mitochondrion,-,-,-
125150,183,27,0,3,45,9,4,59,19,1,47,0,"ZSWIM7;zinc finger, SWIM-type containing 7",GO:0097196//Shu complex;GO:0005634//nucleus,GO:0000724//double-strand break repair via homologous recombination;GO:0050821//protein stabilization,GO:0008270//zinc ion binding;GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation
125170,0,0,0,1,0,0,0,32,0,0,0,0,MIEF2;mitochondrial elongation factor 2,GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0008053//mitochondrial fusion;GO:0090314//positive regulation of protein targeting to membrane;GO:0032464//positive regulation of protein homooligomerization;GO:0090141//positive regulation of mitochondrial fission;GO:0007005//mitochondrion organization,GO:0005515//protein binding,-
125206,0,43,88,120,162,0,47,269,39,1,552,0,"SLC5A10;solute carrier family 5 (sodium/sugar cotransporter), member 10",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0006814//sodium ion transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
125228,0,0,0,0,0,0,10,0,36,0,5,0,"FAM210A;family with sequence similarity 210, member A",GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K06264//ECM-receptor interaction
125336,0,0,59,0,0,48,31,33,89,7,15,0,LOXHD1;lipoxygenase homology domains 1,GO:0016020//membrane;GO:0032420//stereocilium,GO:0007605//sensory perception of sound;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport,GO:0005262//calcium channel activity,K10366//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Viral myocarditis;Dilated cardiomyopathy
125476,0,0,1,2,45,0,0,27,0,0,0,0,INO80C;INO80 complex subunit C,GO:0005730//nucleolus;GO:0071339//MLL1 complex;GO:0031011//Ino80 complex,"GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling",-,-
125488,0,0,0,5,19,1,1,64,98,0,10,0,TTC39C;tetratricopeptide repeat domain 39C,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
125704,42,0,0,0,0,0,0,0,46,0,1,0,"FAM69C;family with sequence similarity 69, member C",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0008152//metabolic process,"GO:0016772//transferase activity, transferring phosphorus-containing groups",-
1258,0,0,0,0,0,56,14,88,32,138,18,498,CNGB1;cyclic nucleotide gated channel beta 1,GO:0005887//integral component of plasma membrane;GO:0043195//terminal bouton;GO:0005886//plasma membrane;GO:1902495//transmembrane transporter complex,"GO:0071805//potassium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0051480//cytosolic calcium ion homeostasis;GO:0006812//cation transport;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light;GO:0007608//sensory perception of smell;GO:0051290//protein heterotetramerization;GO:0001895//retina homeostasis;GO:0050908//detection of light stimulus involved in visual perception;GO:0006810//transport;GO:0007601//visual perception",GO:0005249//voltage-gated potassium channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0005515//protein binding;GO:0030552//cAMP binding;GO:0015276//ligand-gated ion channel activity;GO:0030553//cGMP binding,K04952//Olfactory transduction;Phototransduction
125875,0,0,0,0,3,0,0,0,0,0,0,0,CLDND2;claudin domain containing 2,GO:0016021//integral component of membrane,-,-,-
125893,22,0,0,2,54,0,0,0,48,0,0,0,ZNF816;zinc finger protein 816,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
1259,0,0,0,0,0,30,0,0,8,0,0,0,CNGA1;cyclic nucleotide gated channel alpha 1,GO:0042622//photoreceptor outer segment membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0007601//visual perception;GO:0006810//transport;GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway",GO:0005515//protein binding;GO:0030553//cGMP binding;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005222//intracellular cAMP activated cation channel activity,K04948//Phototransduction
125919,104,0,0,0,13,0,65,0,0,0,0,446,ZNF543;zinc finger protein 543,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
125931,0,0,0,0,1,10,27,0,25,0,0,0,CEACAM20;carcinoembryonic antigen-related cell adhesion molecule 20,GO:0016021//integral component of membrane,-,-,-
125950,0,0,0,1,0,3,0,10,58,57,0,0,"RAVER1;ribonucleoprotein, PTB-binding 1",GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K11219//Influenza A;Jak-STAT signaling pathway;Measles;Epstein-Barr virus infection;Osteoclast differentiation;Toxoplasmosis;Herpes simplex infection;Hepatitis C
125958,0,0,0,0,0,5,0,0,18,0,0,0,"OR7D4;olfactory receptor, family 7, subfamily D, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
125962,0,0,0,0,0,0,5,0,10,0,0,0,"OR7G1;olfactory receptor, family 7, subfamily G, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
125965,55,0,0,0,3,0,2,0,0,50,0,1,COX6B2;cytochrome c oxidase subunit VIb polypeptide 2 (testis),GO:0030061//mitochondrial crista;GO:0005758//mitochondrial intermembrane space,GO:1902600//hydrogen ion transmembrane transport,GO:0004129//cytochrome-c oxidase activity,K02267//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;Cardiac muscle contraction
125972,0,0,0,0,0,0,10,0,13,0,0,0,CALR3;calreticulin 3,GO:0005788//endoplasmic reticulum lumen,GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0006457//protein folding,GO:0030246//carbohydrate binding;GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding;GO:0044183//protein binding involved in protein folding,-
125981,0,0,0,0,0,10,2,0,16,0,12,0,ACER1;alkaline ceramidase 1,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006665//sphingolipid metabolic process;GO:0030216//keratinocyte differentiation;GO:0008544//epidermis development;GO:0019216//regulation of lipid metabolic process;GO:0010446//response to alkaline pH;GO:0030154//cell differentiation;GO:0046514//ceramide catabolic process;GO:0071277//cellular response to calcium ion;GO:0046512//sphingosine biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0017040//ceramidase activity;GO:0071633//dihydroceramidase activity,K01441//Sphingolipid metabolism;Metabolic pathways
125988,0,30,0,1,1,0,13,75,0,0,9,0,C19orf70;chromosome 19 open reading frame 70,GO:0005739//mitochondrion,-,-,K06481//Small cell lung cancer;Dilated cardiomyopathy;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Focal adhesion;Hematopoietic cell lineage;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM)
125997,0,0,0,0,13,0,0,2,0,0,0,0,MBD3L2;methyl-CpG binding domain protein 3-like 2,-,-,-,-
126,0,0,0,0,1,8,12,17,28,0,0,0,"ADH1C;alcohol dehydrogenase 1C (class I), gamma polypeptide",GO:0005829//cytosol,GO:0006069//ethanol oxidation;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0008270//zinc ion binding,K13951//Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Glycolysis / Gluconeogenesis;Fatty acid metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Tyrosine metabolism
1260,51,0,0,0,0,16,20,0,61,0,1,0,CNGA2;cyclic nucleotide gated channel alpha 2,GO:0005887//integral component of plasma membrane,"GO:0007608//sensory perception of smell;GO:0007603//phototransduction, visible light;GO:0071805//potassium ion transmembrane transport;GO:0042391//regulation of membrane potential",GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005516//calmodulin binding,-
126003,0,1,0,0,13,0,0,0,0,0,0,0,TRAPPC5;trafficking protein particle complex 5,GO:0030008//TRAPP complex;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0016192//vesicle-mediated transport,-,-
126006,1,0,0,0,0,3,9,56,0,0,0,1,PCP2;Purkinje cell protein 2,GO:0043025//neuronal cell body,GO:0016056//rhodopsin mediated signaling pathway;GO:0043547//positive regulation of GTPase activity,GO:0030695//GTPase regulator activity;GO:0005085//guanyl-nucleotide exchange factor activity,K15839//Cocaine addiction
126014,0,0,8,0,0,22,0,0,1,0,28,0,"OSCAR;osteoclast associated, immunoglobulin-like receptor",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,-,K14377//Osteoclast differentiation
126017,34,1,2,23,97,0,23,0,42,0,15,0,ZNF813;zinc finger protein 813,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
126068,0,0,0,20,6,22,0,0,20,0,0,0,ZNF441;zinc finger protein 441,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
126069,0,0,0,0,25,0,0,0,56,0,0,0,ZNF491;zinc finger protein 491,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
126070,0,31,0,4,0,0,26,0,14,0,0,0,ZNF440;zinc finger protein 440,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
126074,0,48,0,13,17,0,0,0,6,0,19,0,SWSAP1;SWIM-type zinc finger 7 associated protein 1,GO:0097196//Shu complex;GO:0005634//nucleus,GO:0006200//ATP catabolic process;GO:0000724//double-strand break repair via homologous recombination;GO:0050821//protein stabilization,GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
126075,0,0,0,3,6,0,0,1,0,0,0,0,CCDC159;coiled-coil domain containing 159,-,-,-,-
1261,0,0,0,0,0,18,22,25,32,0,0,0,CNGA3;cyclic nucleotide gated channel alpha 3,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0042622//photoreceptor outer segment membrane;GO:1902495//transmembrane transporter complex,"GO:0031960//response to corticosteroid;GO:0051591//response to cAMP;GO:0032026//response to magnesium ion;GO:0007601//visual perception;GO:0007165//signal transduction;GO:0006810//transport;GO:0006812//cation transport;GO:0007603//phototransduction, visible light;GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0046549//retinal cone cell development",GO:0030553//cGMP binding;GO:0015276//ligand-gated ion channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005249//voltage-gated potassium channel activity,K04950//Olfactory transduction
126123,0,0,0,0,0,24,0,0,0,0,0,0,IZUMO2;IZUMO family member 2,GO:0016021//integral component of membrane,-,-,K13349//Peroxisome
126129,0,0,0,0,0,15,1,0,49,0,2,0,CPT1C;carnitine palmitoyltransferase 1C,GO:0030054//cell junction;GO:0045202//synapse;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0009437//carnitine metabolic process;GO:0006635//fatty acid beta-oxidation,GO:0004095//carnitine O-palmitoyltransferase activity,K08765//Adipocytokine signaling pathway;PPAR signaling pathway;Fatty acid metabolism
126133,0,0,28,0,0,29,2,1,43,53,0,0,"ALDH16A1;aldehyde dehydrogenase 16 family, member A1",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0055114//oxidation-reduction process,"GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor","K00128//Two-component system;Propanoate metabolism;Pyruvate metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Arginine and proline metabolism;Lysine degradation;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Ascorbate and aldarate metabolism;Histidine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Tryptophan metabolism;Glycerolipid metabolism;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Limonene and pinene degradation;Bacterial chemotaxis;Glycolysis / Gluconeogenesis;K07249//Metabolic pathways;Retinol metabolism"
126147,0,0,0,0,0,2,0,49,1,171,0,1,NTN5;netrin 5,GO:0005576//extracellular region,-,-,K06843//Axon guidance
1262,0,0,0,0,0,0,0,67,5,0,0,1,CNGA4;cyclic nucleotide gated channel alpha 4,GO:0005887//integral component of plasma membrane,"GO:0007603//phototransduction, visible light;GO:0007608//sensory perception of smell;GO:0071805//potassium ion transmembrane transport;GO:0042391//regulation of membrane potential",GO:0005222//intracellular cAMP activated cation channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0030553//cGMP binding;GO:0030552//cAMP binding,K04951//Olfactory transduction
126204,0,0,0,0,0,0,42,0,27,0,0,0,"NLRP13;NLR family, pyrin domain containing 13",-,-,GO:0005524//ATP binding,K12800//NOD-like receptor signaling pathway;Influenza A;Pertussis
126205,61,0,0,0,0,29,0,0,54,0,0,0,"NLRP8;NLR family, pyrin domain containing 8",GO:0005737//cytoplasm,GO:0070997//neuron death,GO:0005524//ATP binding,K12800//Pertussis;Influenza A;NOD-like receptor signaling pathway
126206,0,0,0,0,0,0,0,0,76,0,0,0,"NLRP5;NLR family, pyrin domain containing 5",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0045179//apical cortex;GO:0043234//protein complex,GO:0009566//fertilization;GO:0009887//organ morphogenesis;GO:0031647//regulation of protein stability;GO:0007566//embryo implantation;GO:0034613//cellular protein localization;GO:0043487//regulation of RNA stability;GO:0070997//neuron death;GO:0001701//in utero embryonic development;GO:0043623//cellular protein complex assembly,GO:0005524//ATP binding,K12800//Influenza A;NOD-like receptor signaling pathway;Pertussis
126208,0,0,0,2,11,0,46,0,9,0,0,0,ZNF787;zinc finger protein 787,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
126231,0,0,0,0,27,32,0,0,8,0,0,0,ZNF573;zinc finger protein 573,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
126248,0,30,0,1,0,0,0,0,12,125,22,0,WDR88;WD repeat domain 88,-,-,-,K12857//Spliceosome
126259,0,0,0,0,0,0,5,0,0,0,0,0,TMIGD2;transmembrane and immunoglobulin domain containing 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042104//positive regulation of activated T cell proliferation;GO:0007165//signal transduction;GO:0001819//positive regulation of cytokine production;GO:0031295//T cell costimulation,GO:0015026//coreceptor activity;GO:0005515//protein binding,-
126282,0,0,0,0,0,0,0,63,33,0,0,0,"TNFAIP8L1;tumor necrosis factor, alpha-induced protein 8-like 1",GO:0005737//cytoplasm,GO:0032007//negative regulation of TOR signaling,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
126295,0,0,0,18,22,7,34,0,19,0,0,0,ZNF57;zinc finger protein 57,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
126298,0,0,0,1,7,0,0,98,11,25,21,0,"IRGQ;immunity-related GTPase family, Q",-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
126299,0,0,0,2,5,0,12,0,1,0,8,0,ZNF428;zinc finger protein 428,-,-,GO:0046872//metal ion binding,-
1263,65,0,0,0,0,0,0,0,0,0,10,0,PLK3;polo-like kinase 3,GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005795//Golgi stack;GO:0030425//dendrite;GO:0005730//nucleolus,GO:0043066//negative regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031122//cytoplasmic microtubule organization;GO:0007113//endomitotic cell cycle;GO:0043491//protein kinase B signaling;GO:0007093//mitotic cell cycle checkpoint;GO:0000302//response to reactive oxygen species;GO:0090316//positive regulation of intracellular protein transport;GO:2000777//positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia;GO:0006915//apoptotic process;GO:0009314//response to radiation;GO:0006468//protein phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006970//response to osmotic stress;GO:0051302//regulation of cell division;GO:0006974//cellular response to DNA damage stimulus;GO:0090166//Golgi disassembly;GO:0000082//G1/S transition of mitotic cell cycle;GO:0032465//regulation of cytokinesis,GO:0004674//protein serine/threonine kinase activity;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0005524//ATP binding,K08862//Tuberculosis
126308,0,0,1,8,11,0,0,0,22,0,9,0,MOB3A;MOB kinase activator 3A,GO:0005622//intracellular,-,GO:0046872//metal ion binding,K04372//Insulin signaling pathway;MAPK signaling pathway;K06685//Cell cycle - yeast
126321,0,0,0,0,0,0,4,0,7,0,0,0,MFSD12;major facilitator superfamily domain containing 12,GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
126326,83,0,0,0,0,0,0,0,24,150,0,0,"GIPC3;GIPC PDZ domain containing family, member 3",-,-,-,K05185//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
126328,0,0,0,0,11,0,1,1,0,0,15,6,"NDUFA11;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain,-,K03956//Metabolic pathways;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease
126353,52,0,0,0,0,0,7,47,0,0,4,0,MISP;mitotic spindle positioning,GO:0005925//focal adhesion;GO:0005938//cell cortex;GO:0005856//cytoskeleton,GO:0007067//mitotic nuclear division,GO:0003779//actin binding,-
126364,143,0,0,0,0,0,0,0,0,0,3,0,LRRC25;leucine rich repeat containing 25,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
126374,166,0,0,0,0,0,0,0,21,0,1,0,WTIP;Wilms tumor 1 interacting protein,GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005912//adherens junction,"GO:0035195//gene silencing by miRNA;GO:0022604//regulation of cell morphogenesis;GO:2000637//positive regulation of gene silencing by miRNA;GO:0035331//negative regulation of hippo signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0001666//response to hypoxia;GO:0007010//cytoskeleton organization",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity,K12792//NOD-like receptor signaling pathway
126375,63,0,0,7,2,28,21,5,57,0,0,485,ZNF792;zinc finger protein 792,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
126382,0,82,104,114,104,0,39,406,41,0,283,0,NR2C2AP;nuclear receptor 2C2-associated protein,GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm,GO:0010467//gene expression;GO:0007155//cell adhesion;GO:0006367//transcription initiation from RNA polymerase II promoter,GO:0005515//protein binding,-
126393,12,0,0,0,0,12,8,0,21,0,0,0,"HSPB6;heat shock protein, alpha-crystallin-related, B6",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006950//response to stress;GO:0006937//regulation of muscle contraction,GO:0005212//structural constituent of eye lens;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
1264,0,0,0,0,0,0,0,0,0,0,21,0,"CNN1;calponin 1, basic, smooth muscle",GO:0005856//cytoskeleton;GO:0005925//focal adhesion,GO:0006940//regulation of smooth muscle contraction;GO:0031032//actomyosin structure organization,GO:0003779//actin binding;GO:0005516//calmodulin binding,K06084//Adherens junction
126402,0,0,0,0,0,12,0,0,10,0,0,0,CCDC105;coiled-coil domain containing 105,GO:0070062//extracellular vesicular exosome,-,-,-
126410,0,0,0,0,0,10,12,0,20,0,5,0,"CYP4F22;cytochrome P450, family 4, subfamily F, polypeptide 22",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,"GO:0020037//heme binding;GO:0004497//monooxygenase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding",K00490//Metabolic pathways;Arachidonic acid metabolism
126432,0,0,0,0,0,0,0,0,56,0,4,0,RINL;Ras and Rab interactor-like,GO:0001726//ruffle;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0015629//actin cytoskeleton,GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport;GO:0006897//endocytosis,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity,K11447//Transcriptional misregulation in cancer
126433,0,0,0,1,0,0,0,59,2,0,8,0,FBXO27;F-box protein 27,GO:0019005//SCF ubiquitin ligase complex,-,GO:0001948//glycoprotein binding;GO:0005515//protein binding,-
1265,0,0,1,1,8,0,16,0,30,0,0,0,CNN2;calponin 2,GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0001725//stress fiber;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,GO:0030097//hemopoiesis;GO:0042060//wound healing;GO:0050765//negative regulation of phagocytosis;GO:0010628//positive regulation of gene expression;GO:0071260//cellular response to mechanical stimulus;GO:0007010//cytoskeleton organization;GO:0030336//negative regulation of cell migration;GO:0032970//regulation of actin filament-based process;GO:0042127//regulation of cell proliferation;GO:0031032//actomyosin structure organization,GO:0005516//calmodulin binding;GO:0003779//actin binding,K06084//Adherens junction
126520,0,0,0,3,0,2,0,0,0,0,12,0,PLK5;polo-like kinase 5,GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0010976//positive regulation of neuron projection development;GO:0031572//G2 DNA damage checkpoint;GO:0006927//transformed cell apoptotic process;GO:0007067//mitotic nuclear division;GO:0002357//defense response to tumor cell;GO:0071363//cellular response to growth factor stimulus;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0005524//ATP binding,K08862//Tuberculosis
126526,0,0,0,0,1,0,0,0,11,0,0,0,C19orf47;chromosome 19 open reading frame 47,GO:0005634//nucleus;GO:0005730//nucleolus,-,-,-
126549,101,16,9,0,0,0,0,0,14,0,5,0,ANKLE1;ankyrin repeat and LEM domain containing 1,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
126567,0,0,0,0,0,11,0,0,33,2,3,0,C2CD4C;C2 calcium-dependent domain containing 4C,-,-,-,K08534//Circadian rhythm - mammal
1266,0,1,0,9,81,0,0,12,0,0,0,0,"CNN3;calponin 3, acidic",GO:0005925//focal adhesion,GO:0030855//epithelial cell differentiation;GO:0031032//actomyosin structure organization,GO:0005516//calmodulin binding;GO:0003779//actin binding,K06084//Adherens junction
126626,0,0,0,0,11,0,15,0,29,0,0,0,"GABPB2;GA binding protein transcription factor, beta subunit 2",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0044212//transcription regulatory region DNA binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
126637,0,0,0,0,0,0,30,0,12,0,12,0,TCHHL1;trichohyalin-like 1,-,-,GO:0005509//calcium ion binding,K04573//Amyotrophic lateral sclerosis (ALS);K04574//Amyotrophic lateral sclerosis (ALS);K14572//Ribosome biogenesis in eukaryotes;K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Calcium signaling pathway;Gastric acid secretion
126638,0,0,0,0,0,12,0,0,31,0,0,0,RPTN;repetin,GO:0001533//cornified envelope;GO:0005578//proteinaceous extracellular matrix,-,GO:0005509//calcium ion binding,-
126668,0,0,0,3,4,12,0,5,20,0,6,0,TDRD10;tudor domain containing 10,-,-,GO:0003723//RNA binding;GO:0000166//nucleotide binding,-
126669,211,0,0,0,0,11,25,0,89,0,0,0,SHE;Src homology 2 domain containing E,-,-,GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
126695,0,0,0,0,0,0,15,0,7,0,13,0,KDF1;keratinocyte differentiation factor 1,GO:0030054//cell junction;GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0005938//cell cortex,GO:0016331//morphogenesis of embryonic epithelium;GO:0010839//negative regulation of keratinocyte proliferation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0061436//establishment of skin barrier;GO:0003334//keratinocyte development;GO:2000647//negative regulation of stem cell proliferation;GO:0048589//developmental growth;GO:0010482//regulation of epidermal cell division;GO:0060887//limb epidermis development,-,-
1267,55,42,0,19,41,0,1,1,7,0,0,0,"CNP;2',3'-cyclic nucleotide 3' phosphodiesterase",GO:0005634//nucleus;GO:0005615//extracellular space;GO:0031143//pseudopodium;GO:0005730//nucleolus;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0035748//myelin sheath abaxonal region;GO:0005743//mitochondrial inner membrane;GO:0035749//myelin sheath adaxonal region;GO:0042470//melanosome;GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane,GO:0000226//microtubule cytoskeleton organization;GO:0009214//cyclic nucleotide catabolic process;GO:0007268//synaptic transmission;GO:0032496//response to lipopolysaccharide;GO:0046902//regulation of mitochondrial membrane permeability;GO:0021762//substantia nigra development;GO:0009636//response to toxic substance;GO:0007409//axonogenesis;GO:0048709//oligodendrocyte differentiation;GO:0008344//adult locomotory behavior;GO:0007568//aging,"GO:0004113//2',3'-cyclic-nucleotide 3'-phosphodiesterase activity;GO:0003723//RNA binding;GO:0030551//cyclic nucleotide binding",-
126731,0,27,0,9,47,45,42,0,31,0,1,0,"CCSAP;centriole, cilia and spindle-associated protein",GO:0005930//axoneme;GO:0035869//ciliary transition zone;GO:0030424//axon;GO:0005929//cilium;GO:0005814//centriole;GO:0005813//centrosome;GO:0005819//spindle;GO:0036064//ciliary basal body,GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0007275//multicellular organismal development;GO:0045995//regulation of embryonic development,-,-
126755,0,0,0,0,0,0,0,0,12,0,0,0,LRRC38;leucine rich repeat containing 38,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006811//ion transport,-,K06839//Axon guidance
126767,0,0,0,0,0,0,0,0,12,0,0,0,AADACL3;arylacetamide deacetylase-like 3,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
126789,0,134,30,5,48,0,0,2,0,1,75,0,PUSL1;pseudouridylate synthase-like 1,-,GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing,GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity,-
126792,164,16,34,0,0,0,0,66,5,0,0,0,"B3GALT6;UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6",GO:0005797//Golgi medial cisterna;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0030204//chondroitin sulfate metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006486//protein glycosylation;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047220//galactosylxylosylprotein 3-beta-galactosyltransferase activity",K00734//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
1268,0,0,0,0,0,0,0,4,0,0,4,0,CNR1;cannabinoid receptor 1 (brain),GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0060135//maternal process involved in female pregnancy;GO:0007584//response to nutrient;GO:0038171//cannabinoid signaling pathway;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0033004//negative regulation of mast cell activation;GO:0007568//aging;GO:0060259//regulation of feeding behavior;GO:0033602//negative regulation of dopamine secretion;GO:0043278//response to morphine;GO:0019233//sensory perception of pain;GO:0045759//negative regulation of action potential;GO:0035094//response to nicotine;GO:0010976//positive regulation of neuron projection development;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007613//memory;GO:0045776//negative regulation of blood pressure;GO:0032496//response to lipopolysaccharide;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0050796//regulation of insulin secretion;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0002866//positive regulation of acute inflammatory response to antigenic stimulus;GO:0045777//positive regulation of blood pressure;GO:0060405//regulation of penile erection;GO:0045471//response to ethanol;GO:0031622//positive regulation of fever generation;GO:0042593//glucose homeostasis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0042220//response to cocaine",GO:0004949//cannabinoid receptor activity;GO:0008144//drug binding,K04277//Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
126820,0,0,0,0,0,0,12,126,22,0,0,0,WDR63;WD repeat domain 63,-,-,-,K11143//Huntington's disease
126823,0,0,0,0,18,16,0,0,6,0,25,0,KLHDC9;kelch domain containing 9,-,-,-,-
126859,0,0,0,0,0,0,0,0,52,0,0,0,AXDND1;axonemal dynein light chain domain containing 1,-,-,-,-
126868,18,7,0,0,0,24,0,0,9,0,0,0,MAB21L3;mab-21-like 3 (C. elegans),-,-,-,-
1269,0,0,0,0,0,11,0,48,8,0,0,0,CNR2;cannabinoid receptor 2 (macrophage),GO:0005887//integral component of plasma membrane;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0043204//perikaryon;GO:0030425//dendrite;GO:0005886//plasma membrane,"GO:0006954//inflammatory response;GO:0001975//response to amphetamine;GO:0019233//sensory perception of pain;GO:0045759//negative regulation of action potential;GO:0032496//response to lipopolysaccharide;GO:0006955//immune response;GO:0038171//cannabinoid signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0050728//negative regulation of inflammatory response;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0033004//negative regulation of mast cell activation;GO:0032229//negative regulation of synaptic transmission, GABAergic",GO:0004949//cannabinoid receptor activity,K04278//Neuroactive ligand-receptor interaction
126917,0,16,2,6,0,22,0,57,13,66,0,0,IFFO2;intermediate filament family orphan 2,GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,"K07606//Epstein-Barr virus infection;K00294//Alanine, aspartate and glutamate metabolism;Metabolic pathways;Arginine and proline metabolism"
126969,0,0,0,0,0,0,0,0,23,0,0,0,"SLC44A3;solute carrier family 44, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0044281//small molecule metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0055085//transmembrane transport;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,-,-
127,0,0,0,0,0,15,0,0,36,0,0,0,"ADH4;alcohol dehydrogenase 4 (class II), pi polypeptide",GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0046164//alcohol catabolic process;GO:1901661//quinone metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0006069//ethanol oxidation;GO:0006066//alcohol metabolic process,"GO:0019115//benzaldehyde dehydrogenase activity;GO:0004745//retinol dehydrogenase activity;GO:0005503//all-trans retinal binding;GO:0051287//NAD binding;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0003960//NADPH:quinone reductase activity;GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0035276//ethanol binding;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0019841//retinol binding;GO:0008270//zinc ion binding",K13980//Drug metabolism - cytochrome P450;Metabolic pathways;Tyrosine metabolism;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Fatty acid metabolism;Glycolysis / Gluconeogenesis
127002,0,0,0,0,0,0,0,0,39,0,10,0,ATXN7L2;ataxin 7-like 2,-,-,-,-
127003,0,19,0,0,0,0,0,0,17,0,0,0,C1orf194;chromosome 1 open reading frame 194,-,-,-,-
127018,0,0,0,0,8,0,0,0,0,0,0,0,LYPLAL1;lysophospholipase-like 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0002084//protein depalmitoylation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport,GO:0004622//lysophospholipase activity,-
127059,0,0,0,0,0,22,36,0,0,0,0,0,"OR2M5;olfactory receptor, family 2, subfamily M, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
127062,0,0,20,0,0,0,0,0,3,0,0,0,"OR2M3;olfactory receptor, family 2, subfamily M, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
127064,0,0,0,0,0,15,0,0,0,0,0,0,"OR2T12;olfactory receptor, family 2, subfamily T, member 12",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
127068,0,0,0,0,0,1,0,0,0,0,0,0,"OR2T34;olfactory receptor, family 2, subfamily T, member 34",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
127069,0,0,0,0,0,0,0,0,16,0,0,0,"OR2T10;olfactory receptor, family 2, subfamily T, member 10",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1271,0,0,0,0,0,34,6,68,11,0,0,0,CNTFR;ciliary neurotrophic factor receptor,GO:0031225//anchored component of membrane;GO:0019898//extrinsic component of membrane;GO:0005886//plasma membrane;GO:0097059//CNTFR-CLCF1 complex,GO:0001967//suckling behavior;GO:0007548//sex differentiation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0060538//skeletal muscle organ development;GO:0007399//nervous system development;GO:0003360//brainstem development,GO:0004897//ciliary neurotrophic factor receptor activity;GO:0019955//cytokine binding;GO:0005102//receptor binding,K05059//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
127124,0,0,0,0,0,6,0,0,10,0,0,0,"ATP6V1G3;ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3",GO:0005886//plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005829//cytosol,GO:0055085//transmembrane transport;GO:0008286//insulin receptor signaling pathway;GO:0006879//cellular iron ion homeostasis;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0051701//interaction with host;GO:1902600//hydrogen ion transmembrane transport,"GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0051117//ATPase binding",K02152//Synaptic vesicle cycle;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Oxidative phosphorylation;Metabolic pathways
1272,0,0,0,0,0,0,20,0,75,0,0,0,CNTN1;contactin 1,GO:0031225//anchored component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0010765//positive regulation of sodium ion transport;GO:0021549//cerebellum development;GO:0010976//positive regulation of neuron projection development;GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway;GO:0007411//axon guidance;GO:0010628//positive regulation of gene expression,GO:0001948//glycoprotein binding;GO:0030246//carbohydrate binding,K06759//Cell adhesion molecules (CAMs)
127253,0,47,0,37,57,0,0,0,27,0,0,0,TYW3;tRNA-yW synthesizing protein 3 homolog (S. cerevisiae),-,GO:0008033//tRNA processing;GO:0032259//methylation,GO:0008168//methyltransferase activity,-
127254,0,0,1,2,1,12,101,0,47,123,9,39,ERICH3;glutamate-rich 3,-,-,-,-
127255,0,0,0,0,0,0,5,0,48,2,0,0,LRRIQ3;leucine-rich repeats and IQ motif containing 3,-,-,-,-
127262,0,2,0,0,19,0,22,52,0,0,6,0,TPRG1L;tumor protein p63 regulated 1-like,GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome,-,GO:0042802//identical protein binding,-
127281,0,0,0,0,20,0,0,0,0,0,0,0,"FAM213B;family with sequence similarity 213, member B",GO:0005737//cytoplasm;GO:0043209//myelin sheath;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,GO:0044281//small molecule metabolic process;GO:0019371//cyclooxygenase pathway;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0001516//prostaglandin biosynthetic process,"GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0047017//prostaglandin-F synthase activity",K15717//Arachidonic acid metabolism;Metabolic pathways
127294,204,0,0,0,0,0,42,83,91,0,10,0,MYOM3;myomesin 3,GO:0031430//M band,-,GO:0042803//protein homodimerization activity,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
127343,0,0,0,0,0,27,0,0,16,0,8,0,DMBX1;diencephalon/mesencephalon homeobox 1,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0007420//brain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0008343//adult feeding behavior;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0048589//developmental growth;GO:0008344//adult locomotory behavior",GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,-
127385,0,0,0,0,0,10,0,0,9,0,0,0,"OR10J5;olfactory receptor, family 10, subfamily J, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
127396,0,0,0,0,0,17,0,0,30,0,0,0,ZNF684;zinc finger protein 684,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
127428,0,1,54,17,15,15,22,0,24,0,0,0,TCEANC2;transcription elongation factor A (SII) N-terminal and central domain containing 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
127435,0,0,0,4,0,0,6,0,2,0,0,0,PODN;podocan,GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm,GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation,GO:0005518//collagen binding,K08764//PPAR signaling pathway;Primary bile acid biosynthesis;Metabolic pathways;Peroxisome
127495,90,0,0,24,61,0,0,66,10,0,0,0,LRRC39;leucine rich repeat containing 39,-,-,-,K12796//NOD-like receptor signaling pathway
127534,0,0,0,0,0,6,0,0,38,0,6,0,"GJB4;gap junction protein, beta 4, 30.3kDa",GO:0016021//integral component of membrane;GO:0005922//connexon complex,GO:0042048//olfactory behavior;GO:0007608//sensory perception of smell;GO:0007154//cell communication,-,-
127544,0,0,0,0,0,0,0,0,11,0,0,0,RNF19B;ring finger protein 19B,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0044194//cytolytic granule,GO:0072643//interferon-gamma secretion;GO:0042267//natural killer cell mediated cytotoxicity;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,-
127550,0,0,0,0,0,0,0,0,14,0,4,44,"A3GALT2;alpha 1,3-galactosyltransferase 2",-,-,-,K00743//Glycosphingolipid biosynthesis - lacto and neolacto series
127579,0,0,0,0,14,0,40,54,17,114,14,0,DCST2;DC-STAMP domain containing 2,GO:0016021//integral component of membrane,-,-,K14315//RNA transport
127602,66,37,0,8,56,48,93,0,185,0,0,0,"DNAH14;dynein, axonemal, heavy chain 14",GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm;GO:0005929//cilium,GO:0008152//metabolic process;GO:0007018//microtubule-based movement,GO:0005524//ATP binding;GO:0003777//microtubule motor activity,K10408//Huntington's disease
127665,0,0,0,0,0,0,0,0,45,0,0,0,ZNF648;zinc finger protein 648,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
127670,0,0,0,0,0,20,0,0,21,0,0,0,TEDDM1;transmembrane epididymal protein 1,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
127687,1,115,2,19,36,0,10,171,9,0,57,3,C1orf122;chromosome 1 open reading frame 122,-,-,-,-
1277,80,14,0,0,0,66,0,0,66,0,12,0,"COL1A1;collagen, type I, alpha 1",GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005584//collagen type I trimer;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0030335//positive regulation of cell migration;GO:0015031//protein transport;GO:0060325//face morphogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031960//response to corticosteroid;GO:0007605//sensory perception of sound;GO:0043589//skin morphogenesis;GO:0034504//protein localization to nucleus;GO:0007584//response to nutrient;GO:0010812//negative regulation of cell-substrate adhesion;GO:0071260//cellular response to mechanical stimulus;GO:0043434//response to peptide hormone;GO:0051591//response to cAMP;GO:0001958//endochondral ossification;GO:0022617//extracellular matrix disassembly;GO:0050900//leukocyte migration;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001957//intramembranous ossification;GO:0030199//collagen fibril organization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0042542//response to hydrogen peroxide;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0070208//protein heterotrimerization;GO:0001568//blood vessel development;GO:0060346//bone trabecula formation;GO:0071300//cellular response to retinoic acid;GO:0001501//skeletal system development;GO:0007596//blood coagulation;GO:0030574//collagen catabolic process;GO:0034505//tooth mineralization;GO:0048706//embryonic skeletal system development;GO:0001649//osteoblast differentiation;GO:0032964//collagen biosynthetic process;GO:0007601//visual perception;GO:0032355//response to estradiol;GO:0030168//platelet activation;GO:0060351//cartilage development involved in endochondral bone morphogenesis",GO:0042802//identical protein binding;GO:0005201//extracellular matrix structural constituent;GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K06236//ECM-receptor interaction;Protein digestion and absorption;Amoebiasis;Focal adhesion
127700,0,0,0,4,0,16,0,0,12,0,17,0,OSCP1;organic solute carrier partner 1,GO:0009925//basal plasma membrane,GO:0006810//transport,-,-
127703,0,0,0,0,10,32,0,0,14,0,0,0,C1orf216;chromosome 1 open reading frame 216,-,-,-,-
127707,3,0,0,0,0,0,0,0,12,0,0,0,KLHDC7A;kelch domain containing 7A,GO:0016021//integral component of membrane,-,-,-
127731,171,0,0,0,0,23,76,26,79,0,3,290,VWA5B1;von Willebrand factor A domain containing 5B1,GO:0005576//extracellular region,-,-,K10798//NF-kappa B signaling pathway;Base excision repair
127733,43,0,0,7,0,32,0,0,20,0,0,0,UBXN10;UBX domain protein 10,-,-,-,-
127795,0,0,0,0,0,0,0,0,32,0,0,0,C1orf87;chromosome 1 open reading frame 87,-,-,GO:0005509//calcium ion binding,-
1278,0,0,0,0,0,12,70,0,24,0,13,0,"COL1A2;collagen, type I, alpha 2",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0005584//collagen type I trimer,GO:0030574//collagen catabolic process;GO:0007596//blood coagulation;GO:0001501//skeletal system development;GO:0043589//skin morphogenesis;GO:0008217//regulation of blood pressure;GO:0007266//Rho protein signal transduction;GO:0030168//platelet activation;GO:0050900//leukocyte migration;GO:0022617//extracellular matrix disassembly;GO:0042476//odontogenesis;GO:0030199//collagen fibril organization;GO:0001568//blood vessel development;GO:0070208//protein heterotrimerization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization,"GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0042802//identical protein binding;GO:0030674//protein binding, bridging;GO:0046332//SMAD binding",K06236//Protein digestion and absorption;Amoebiasis;Focal adhesion;ECM-receptor interaction
127829,8,0,0,15,30,9,43,0,18,0,6,0,ARL8A;ADP-ribosylation factor-like 8A,GO:0030496//midbody;GO:0070062//extracellular vesicular exosome;GO:0051233//spindle midzone;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding,-
127833,91,0,0,0,0,16,1,180,0,0,6,169,SYT2;synaptotagmin II,GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0042584//chromaffin granule membrane,GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
127845,0,0,0,0,0,0,33,0,3,176,2,0,GOLT1A;golgi transport 1A,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0016192//vesicle-mediated transport;GO:0015031//protein transport,-,K00923//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
127933,0,75,0,122,225,0,12,0,93,0,0,0,UHMK1;U2AF homology motif (UHM) kinase 1,GO:0030424//axon;GO:0032839//dendrite cytoplasm;GO:0005634//nucleus;GO:0071598//neuronal ribonucleoprotein granule,GO:0018105//peptidyl-serine phosphorylation;GO:0007050//cell cycle arrest;GO:0046825//regulation of protein export from nucleus;GO:0046777//protein autophosphorylation;GO:0031175//neuron projection development;GO:0045948//positive regulation of translational initiation,GO:0043021//ribonucleoprotein complex binding;GO:0004674//protein serine/threonine kinase activity;GO:0016740//transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0019899//enzyme binding,-
127943,0,0,0,0,0,44,0,0,16,0,9,0,FCRLB;Fc receptor-like B,GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm,GO:0050777//negative regulation of immune response,-,K06472//Fc gamma R-mediated phagocytosis;Tuberculosis;Osteoclast differentiation;Systemic lupus erythematosus;Leishmaniasis;Staphylococcus aureus infection;Phagosome;K06498//Staphylococcus aureus infection;Hematopoietic cell lineage;Osteoclast differentiation;Systemic lupus erythematosus;Leishmaniasis;Phagosome;Transcriptional misregulation in cancer;Fc gamma R-mediated phagocytosis;Tuberculosis;K08089//Fc epsilon RI signaling pathway;Asthma
128,180,42,101,32,102,15,0,0,53,44,0,0,"ADH5;alcohol dehydrogenase 5 (class III), chi polypeptide",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0001523//retinoid metabolic process;GO:0046294//formaldehyde catabolic process;GO:0007568//aging;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0003016//respiratory system process;GO:0006068//ethanol catabolic process;GO:0032496//response to lipopolysaccharide;GO:0006069//ethanol oxidation;GO:0051775//response to redox state;GO:0051409//response to nitrosative stress;GO:0045777//positive regulation of blood pressure,GO:0009055//electron carrier activity;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0005504//fatty acid binding;GO:0051903//S-(hydroxymethyl)glutathione dehydrogenase activity;GO:0018467//formaldehyde dehydrogenase activity;GO:0004022//alcohol dehydrogenase (NAD) activity,K00121//Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Tyrosine metabolism;Naphthalene degradation;Methane metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments
1280,171,0,0,0,7,17,0,54,38,14,3,0,"COL2A1;collagen, type II, alpha 1",GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix,GO:0001958//endochondral ossification;GO:0022617//extracellular matrix disassembly;GO:0003007//heart morphogenesis;GO:0007601//visual perception;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0001501//skeletal system development;GO:0071599//otic vesicle development;GO:0010468//regulation of gene expression;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0030574//collagen catabolic process;GO:0001502//cartilage condensation;GO:0030198//extracellular matrix organization;GO:0042472//inner ear morphogenesis;GO:0001894//tissue homeostasis;GO:0007605//sensory perception of sound;GO:0006029//proteoglycan metabolic process;GO:0051216//cartilage development;GO:0071773//cellular response to BMP stimulus;GO:0030903//notochord development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060174//limb bud formation;GO:0030199//collagen fibril organization;GO:0060021//palate development;GO:0007417//central nervous system development;GO:0007411//axon guidance;GO:0002062//chondrocyte differentiation,GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength,K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
128025,0,0,0,0,0,41,0,32,47,0,1,0,WDR64;WD repeat domain 64,-,-,-,K10599//Spliceosome;Ubiquitin mediated proteolysis
128077,92,2,0,5,0,0,0,17,6,0,0,1,LIX1L;Lix1 homolog (mouse)-like,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
1281,74,0,0,0,0,14,63,70,91,276,7,508,"COL3A1;collagen, type III, alpha 1",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005586//collagen type III trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen,GO:0043588//skin development;GO:0035025//positive regulation of Rho protein signal transduction;GO:0042060//wound healing;GO:0030199//collagen fibril organization;GO:0007411//axon guidance;GO:0030198//extracellular matrix organization;GO:0071230//cellular response to amino acid stimulus;GO:0043206//extracellular fibril organization;GO:2001223//negative regulation of neuron migration;GO:0018149//peptide cross-linking;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007507//heart development;GO:0048565//digestive tract development;GO:0001568//blood vessel development;GO:0021987//cerebral cortex development;GO:0001501//skeletal system development;GO:0007160//cell-matrix adhesion;GO:0034097//response to cytokine;GO:0009612//response to mechanical stimulus;GO:0009314//response to radiation;GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0007568//aging;GO:0007229//integrin-mediated signaling pathway;GO:0050777//negative regulation of immune response;GO:0030168//platelet activation,GO:0046332//SMAD binding;GO:0048407//platelet-derived growth factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0005178//integrin binding,K06236//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption;Amoebiasis
128102,268,0,35,13,3,0,31,0,32,0,13,1,"HSD3BP4;hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 4",-,-,-,K00070//Metabolic pathways;Steroid hormone biosynthesis
128153,0,0,0,0,0,0,17,0,18,0,0,0,SPATA17;spermatogenesis associated 17,GO:0005737//cytoplasm,-,GO:0005516//calmodulin binding,-
128178,0,36,9,0,1,0,23,20,30,0,9,0,EDARADD;EDAR-associated death domain,GO:0005737//cytoplasm,GO:0042475//odontogenesis of dentin-containing tooth;GO:0001942//hair follicle development;GO:0061153//trachea gland development;GO:0030154//cell differentiation;GO:0007165//signal transduction,-,K01689//Glycolysis / Gluconeogenesis;Methane metabolism;Biosynthesis of secondary metabolites;RNA degradation;Metabolic pathways;Microbial metabolism in diverse environments
1282,143,0,0,0,0,12,20,0,140,121,13,0,"COL4A1;collagen, type IV, alpha 1",GO:0005587//collagen type IV trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005604//basement membrane;GO:0005576//extracellular region,GO:0007528//neuromuscular junction development;GO:0061304//retinal blood vessel morphogenesis;GO:0001569//patterning of blood vessels;GO:0030198//extracellular matrix organization;GO:0071230//cellular response to amino acid stimulus;GO:0048514//blood vessel morphogenesis;GO:0061333//renal tubule morphogenesis;GO:0022617//extracellular matrix disassembly;GO:0007411//axon guidance;GO:0007420//brain development;GO:0071711//basement membrane organization;GO:0030855//epithelial cell differentiation;GO:0030574//collagen catabolic process,GO:0048407//platelet-derived growth factor binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0030023//extracellular matrix constituent conferring elasticity,K06237//Small cell lung cancer;Protein digestion and absorption;Amoebiasis;Focal adhesion;Pathways in cancer;ECM-receptor interaction
128209,0,0,0,0,0,0,0,0,24,0,15,0,KLF17;Kruppel-like factor 17,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007276//gamete generation;GO:0006351//transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
128218,0,1,0,0,45,0,0,0,12,0,14,0,TMEM125;transmembrane protein 125,GO:0016021//integral component of membrane,-,-,-
128239,83,0,0,0,0,21,48,0,55,0,0,0,IQGAP3;IQ motif containing GTPase activating protein 3,GO:0016328//lateral plasma membrane;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0007265//Ras protein signal transduction;GO:0000082//G1/S transition of mitotic cell cycle;GO:0008361//regulation of cell size;GO:0010629//negative regulation of gene expression;GO:0070371//ERK1 and ERK2 cascade;GO:0071310//cellular response to organic substance;GO:0010628//positive regulation of gene expression;GO:0000187//activation of MAPK activity;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0032320//positive regulation of Ras GTPase activity,GO:0017048//Rho GTPase binding;GO:0005516//calmodulin binding;GO:0005099//Ras GTPase activator activity,K05767//Regulation of actin cytoskeleton;Adherens junction
128240,0,24,0,0,27,0,18,0,0,0,0,0,APOA1BP;apolipoprotein A-I binding protein,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005929//cilium;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0044297//cell body,GO:0008152//metabolic process;GO:0051289//protein homotetramerization,GO:0052856//NADHX epimerase activity;GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
128272,0,0,0,0,0,1,37,32,1,212,5,0,ARHGEF19;Rho guanine nucleotide exchange factor (GEF) 19,-,GO:0032956//regulation of actin cytoskeleton organization;GO:0032321//positive regulation of Rho GTPase activity;GO:0042060//wound healing,GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity,K07525//Axon guidance
128308,0,0,0,0,1,0,0,0,11,0,0,0,MRPL55;mitochondrial ribosomal protein L55,GO:0005762//mitochondrial large ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
128312,0,0,0,0,4,0,0,0,0,0,0,0,"HIST3H2BB;histone cluster 3, H2bb",GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006325//chromatin organization,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Alcoholism;Systemic lupus erythematosus
128338,0,1,0,2,0,19,57,0,15,8,0,0,DRAM2;DNA-damage regulated autophagy modulator 2,GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005764//lysosome;GO:0015630//microtubule cytoskeleton;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm,GO:0010506//regulation of autophagy;GO:0006915//apoptotic process,-,-
128344,0,1,0,0,0,0,0,0,0,0,0,0,PIFO;primary cilia formation,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005802//trans-Golgi network,GO:0030030//cell projection organization;GO:0033674//positive regulation of kinase activity;GO:0031344//regulation of cell projection organization,GO:0017137//Rab GTPase binding;GO:0043015//gamma-tubulin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019894//kinesin binding;GO:0048487//beta-tubulin binding,-
128366,0,0,0,0,0,0,26,0,1,0,0,0,"OR6P1;olfactory receptor, family 6, subfamily P, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
128367,0,0,0,0,0,22,0,0,12,0,0,0,"OR10X1;olfactory receptor, family 10, subfamily X, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
128368,0,0,0,0,0,0,0,0,11,0,0,0,"OR10Z1;olfactory receptor, family 10, subfamily Z, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
128371,0,0,0,0,0,0,0,0,0,0,8,0,"OR6K6;olfactory receptor, family 6, subfamily K, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
128372,0,0,0,0,0,0,0,0,29,0,0,0,"OR6N1;olfactory receptor, family 6, subfamily N, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
128387,0,0,0,0,13,15,0,0,0,0,0,0,TATDN3;TatD DNase domain containing 3,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0043229//intracellular organelle,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006308//DNA catabolic process","GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0046872//metal ion binding;GO:0004536//deoxyribonuclease activity",-
1284,174,0,0,0,0,53,2,0,54,0,0,0,"COL4A2;collagen, type IV, alpha 2",GO:0031012//extracellular matrix;GO:0005587//collagen type IV trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0043231//intracellular membrane-bounded organelle,"GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0016525//negative regulation of angiogenesis;GO:0001525//angiogenesis;GO:0030574//collagen catabolic process;GO:0006351//transcription, DNA-templated;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0035987//endodermal cell differentiation;GO:0007411//axon guidance",GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent,K06237//ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;Amoebiasis;Protein digestion and absorption;Focal adhesion
128414,0,0,0,0,0,10,3,0,0,0,0,28,NKAIN4;Na+/K+ transporting ATPase interacting 4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
128434,1,0,0,0,0,0,0,32,14,0,0,0,VSTM2L;V-set and transmembrane domain containing 2 like,-,-,GO:0005515//protein binding,-
128486,0,0,0,0,0,0,0,0,0,0,15,0,FITM2;fat storage-inducing transmembrane protein 2,GO:0005739//mitochondrion;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0035356//cellular triglyceride homeostasis;GO:0010890//positive regulation of sequestering of triglyceride;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0010866//regulation of triglyceride biosynthetic process;GO:0034389//lipid particle organization,-,-
128497,0,0,0,0,5,0,21,0,6,0,0,0,SPATA25;spermatogenesis associated 25,GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007283//spermatogenesis,-,-
1285,245,0,0,14,0,30,39,0,184,54,14,0,"COL4A3;collagen, type IV, alpha 3 (Goodpasture antigen)",GO:0005587//collagen type IV trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005604//basement membrane,GO:0007411//axon guidance;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0072577//endothelial cell apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0030574//collagen catabolic process;GO:0008283//cell proliferation;GO:0008015//blood circulation;GO:0030198//extracellular matrix organization;GO:0016525//negative regulation of angiogenesis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032836//glomerular basement membrane development;GO:0007605//sensory perception of sound;GO:0022617//extracellular matrix disassembly,GO:0008191//metalloendopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0005198//structural molecule activity,K06237//Amoebiasis;Small cell lung cancer;Protein digestion and absorption;Focal adhesion;Pathways in cancer;ECM-receptor interaction
128553,0,8,24,3,7,61,66,22,94,0,0,0,TSHZ2;teashirt zinc finger homeobox 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
1286,229,0,0,4,0,73,61,0,89,1,15,0,"COL4A4;collagen, type IV, alpha 4",GO:0005788//endoplasmic reticulum lumen;GO:0005587//collagen type IV trimer;GO:0005605//basal lamina;GO:0005576//extracellular region,GO:0007411//axon guidance;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0032836//glomerular basement membrane development,GO:0005201//extracellular matrix structural constituent,K06237//Pathways in cancer;ECM-receptor interaction;Focal adhesion;Small cell lung cancer;Protein digestion and absorption;Amoebiasis
128611,63,0,24,0,0,14,58,0,58,0,0,0,ZNF831;zinc finger protein 831,-,-,GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
128637,3,0,1,15,70,0,0,0,0,0,12,0,"TBC1D20;TBC1 domain family, member 20",GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0030173//integral component of Golgi membrane,GO:0006888//ER to Golgi vesicle-mediated transport;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:0001675//acrosome assembly;GO:0070309//lens fiber cell morphogenesis;GO:0034389//lipid particle organization;GO:0033126//positive regulation of GTP catabolic process;GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity;GO:0072520//seminiferous tubule development;GO:0007030//Golgi organization;GO:0019068//virion assembly,GO:0005515//protein binding;GO:0017137//Rab GTPase binding;GO:0005097//Rab GTPase activator activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
128653,0,0,0,0,0,0,0,0,6,0,0,0,C20orf141;chromosome 20 open reading frame 141,GO:0016021//integral component of membrane,-,-,-
128674,0,0,0,0,0,0,0,0,26,0,0,0,PROKR2;prokineticin receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007623//circadian rhythm;GO:0007218//neuropeptide signaling pathway,GO:0004983//neuropeptide Y receptor activity,-
1287,4,0,0,0,0,8,43,0,86,0,16,0,"COL4A5;collagen, type IV, alpha 5",GO:0005788//endoplasmic reticulum lumen;GO:0005587//collagen type IV trimer;GO:0031594//neuromuscular junction;GO:0005576//extracellular region;GO:0005605//basal lamina,GO:0007528//neuromuscular junction development;GO:0007411//axon guidance;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization,GO:0005201//extracellular matrix structural constituent,K06237//Focal adhesion;Small cell lung cancer;Protein digestion and absorption;Amoebiasis;Pathways in cancer;ECM-receptor interaction
128710,0,0,0,0,28,0,0,0,9,0,0,0,SLX4IP;SLX4 interacting protein,-,-,GO:0005515//protein binding,-
1288,0,0,25,0,10,66,25,34,39,0,14,0,"COL4A6;collagen, type IV, alpha 6",GO:0005587//collagen type IV trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0071230//cellular response to amino acid stimulus;GO:0007155//cell adhesion,GO:0005201//extracellular matrix structural constituent,K06237//Focal adhesion;Small cell lung cancer;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction;Pathways in cancer
128817,0,0,0,0,0,16,0,0,0,0,0,0,CSTL1;cystatin-like 1,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,K13899//Salivary secretion
128821,0,0,0,0,0,0,0,0,14,0,0,84,CST9L;cystatin 9-like,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,-
128822,0,0,0,0,0,0,3,0,6,0,21,0,CST9;cystatin 9 (testatin),GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,-
128826,0,0,1,0,0,0,19,0,22,0,4,0,C20orf166;chromosome 20 open reading frame 166,-,-,-,-
128853,0,0,2,0,0,0,1,1,9,0,0,0,DUSP15;dual specificity phosphatase 15,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0046330//positive regulation of JNK cascade;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0042127//regulation of cell proliferation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding,-
128854,78,0,0,0,1,0,0,0,9,0,1,0,"TSPY26P;testis specific protein, Y-linked 26, pseudogene",GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
128859,0,0,0,0,0,0,0,0,16,0,13,0,"BPIFB6;BPI fold containing family B, member 6",GO:0005576//extracellular region,-,GO:0008289//lipid binding,K05399//Tuberculosis;Toll-like receptor signaling pathway;NF-kappa B signaling pathway;Salmonella infection
128861,0,0,0,0,4,0,0,0,32,0,0,0,"BPIFA3;BPI fold containing family A, member 3",GO:0005576//extracellular region,-,GO:0008289//lipid binding,-
128864,40,0,0,0,11,0,0,0,0,0,12,0,C20orf144;chromosome 20 open reading frame 144,-,-,-,-
128866,0,6,0,10,18,0,0,0,0,0,15,0,CHMP4B;charged multivesicular body protein 4B,GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0030496//midbody;GO:0005737//cytoplasm;GO:0009898//cytoplasmic side of plasma membrane;GO:0000815//ESCRT III complex;GO:0070062//extracellular vesicular exosome,GO:1902902//negative regulation of autophagic vacuole assembly;GO:0061024//membrane organization;GO:0016197//endosomal transport;GO:0006620//posttranslational protein targeting to membrane;GO:1901215//negative regulation of neuron death;GO:0019058//viral life cycle;GO:0050792//regulation of viral process;GO:0016032//viral process;GO:1902188//positive regulation of viral release from host cell;GO:0051260//protein homooligomerization,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity,K12194//Endocytosis
128869,0,0,0,0,0,0,17,85,24,0,0,226,"PIGU;phosphatidylinositol glycan anchor biosynthesis, class U",GO:0042765//GPI-anchor transamidase complex;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification;GO:0016255//attachment of GPI anchor to protein;GO:0006501//C-terminal protein lipidation;GO:0046425//regulation of JAK-STAT cascade;GO:0044267//cellular protein metabolic process,GO:0034235//GPI anchor binding;GO:0003923//GPI-anchor transamidase activity,K05293//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
128876,0,0,0,0,0,28,0,0,20,0,0,1,"FAM83C;family with sequence similarity 83, member C",-,-,-,-
1289,148,0,0,0,10,57,0,52,94,144,9,0,"COL5A1;collagen, type V, alpha 1",GO:0005588//collagen type V trimer;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0030574//collagen catabolic process;GO:0007155//cell adhesion;GO:0022617//extracellular matrix disassembly;GO:0016477//cell migration;GO:0003007//heart morphogenesis;GO:0035313//wound healing, spreading of epidermal cells;GO:0032964//collagen biosynthetic process;GO:0048592//eye morphogenesis;GO:0043588//skin development;GO:0030199//collagen fibril organization;GO:0051128//regulation of cellular component organization;GO:0007411//axon guidance;GO:0030198//extracellular matrix organization;GO:0043206//extracellular fibril organization;GO:0045112//integrin biosynthetic process;GO:0001568//blood vessel development",GO:0048407//platelet-derived growth factor binding;GO:0005201//extracellular matrix structural constituent;GO:0046872//metal ion binding;GO:0005178//integrin binding;GO:0043394//proteoglycan binding;GO:0008201//heparin binding,K06236//Protein digestion and absorption;Amoebiasis;Focal adhesion;ECM-receptor interaction
128954,0,0,0,0,0,10,0,0,61,0,26,0,"GAB4;GRB2-associated binding protein family, member 4",-,-,-,K08091//Fc gamma R-mediated phagocytosis;Chronic myeloid leukemia;Fc epsilon RI signaling pathway;Osteoclast differentiation
128977,0,93,0,26,77,10,0,0,2,0,53,0,C22orf39;chromosome 22 open reading frame 39,-,-,-,-
128989,7,0,0,0,1,0,0,0,22,0,0,0,TANGO2;transport and golgi organization 2 homolog (Drosophila),-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
1290,0,0,0,3,0,61,0,0,198,0,0,0,"COL5A2;collagen, type V, alpha 2",GO:0005576//extracellular region;GO:0005588//collagen type V trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen,GO:0022617//extracellular matrix disassembly;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0048592//eye morphogenesis;GO:0030574//collagen catabolic process;GO:0030199//collagen fibril organization;GO:0001501//skeletal system development;GO:0043588//skin development;GO:0007411//axon guidance,GO:0005201//extracellular matrix structural constituent;GO:0046872//metal ion binding;GO:0046332//SMAD binding,K06236//Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
129025,0,0,0,0,0,0,0,0,17,0,0,0,ZNF280A;zinc finger protein 280A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
129049,0,0,0,0,28,3,0,57,56,0,0,0,SGSM1;small G protein signaling modulator 1,GO:0005794//Golgi apparatus,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K13136//RNA transport
129080,1,0,0,0,14,25,4,0,18,0,14,0,EMID1;EMI domain containing 1,GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer,-,-,K06236//Focal adhesion;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction;K08131//Protein digestion and absorption
1291,0,0,0,0,0,0,26,0,71,24,0,0,"COL6A1;collagen, type VI, alpha 1",GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0042383//sarcolemma;GO:0043234//protein complex;GO:0005589//collagen type VI trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030574//collagen catabolic process;GO:0035987//endodermal cell differentiation;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0022617//extracellular matrix disassembly;GO:0071230//cellular response to amino acid stimulus;GO:0001649//osteoblast differentiation;GO:0030198//extracellular matrix organization;GO:0070208//protein heterotrimerization,GO:0048407//platelet-derived growth factor binding,K06238//Focal adhesion;Protein digestion and absorption;ECM-receptor interaction
129138,0,0,1,0,0,0,0,0,0,0,0,0,ANKRD54;ankyrin repeat domain 54,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030496//midbody,GO:1902531//regulation of intracellular signal transduction;GO:0045859//regulation of protein kinase activity;GO:0045648//positive regulation of erythrocyte differentiation;GO:0006913//nucleocytoplasmic transport,GO:0032403//protein complex binding;GO:0019887//protein kinase regulator activity,-
1292,0,14,0,0,0,11,1,80,58,105,6,0,"COL6A2;collagen, type VI, alpha 2",GO:0042383//sarcolemma;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005581//collagen trimer;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031982//vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0043234//protein complex,GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0070208//protein heterotrimerization;GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0009749//response to glucose,GO:0005515//protein binding,K06238//Focal adhesion;Protein digestion and absorption;ECM-receptor interaction
129285,0,0,0,16,23,0,3,62,53,0,0,0,"PPP1R21;protein phosphatase 1, regulatory subunit 21",GO:0016020//membrane,-,GO:0019902//phosphatase binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
129293,0,0,0,0,0,0,1,24,0,0,0,0,TRABD2A;TraB domain containing 2A,GO:0031301//integral component of organelle membrane;GO:0005887//integral component of plasma membrane,GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008152//metabolic process;GO:0006508//proteolysis;GO:0018158//protein oxidation;GO:0060322//head development,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding;GO:0017147//Wnt-protein binding,-
1293,0,0,0,6,0,65,36,0,101,0,14,44,"COL6A3;collagen, type VI, alpha 3",GO:0042383//sarcolemma;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle;GO:0005589//collagen type VI trimer;GO:0005578//proteinaceous extracellular matrix,GO:0030198//extracellular matrix organization;GO:0009749//response to glucose;GO:0022617//extracellular matrix disassembly;GO:0010951//negative regulation of endopeptidase activity;GO:0030574//collagen catabolic process;GO:0007411//axon guidance;GO:0007155//cell adhesion;GO:0007517//muscle organ development,GO:0004867//serine-type endopeptidase inhibitor activity,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
129303,0,0,0,10,8,0,0,0,9,0,15,0,TMEM150A;transmembrane protein 150A,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0009056//catabolic process,-,-
1294,4,0,41,0,0,88,50,130,80,45,41,1,"COL7A1;collagen, type VII, alpha 1",GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0005576//extracellular region;GO:0005590//collagen type VII trimer;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix,GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0008544//epidermis development;GO:0010951//negative regulation of endopeptidase activity;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K08132//Protein digestion and absorption
129401,0,0,0,11,37,0,0,0,24,0,2,0,NUP35;nucleoporin 35kDa,GO:0031965//nuclear membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton,GO:0015758//glucose transport;GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0044281//small molecule metabolic process,-,K14313//RNA transport
129446,0,0,0,0,0,0,19,0,34,0,0,0,XIRP2;xin actin-binding repeat containing 2,GO:0030054//cell junction;GO:0030018//Z disc,GO:0055008//cardiac muscle tissue morphogenesis;GO:0030036//actin cytoskeleton organization;GO:0003281//ventricular septum development;GO:0045216//cell-cell junction organization,GO:0051393//alpha-actinin binding;GO:0003779//actin binding,-
129450,0,0,0,4,61,12,0,37,54,0,0,0,TYW5;tRNA-yW synthesizing protein 5,-,GO:0055114//oxidation-reduction process;GO:0031591//wybutosine biosynthetic process,"GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0042803//protein homodimerization activity;GO:0000049//tRNA binding",K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
1295,0,0,0,0,0,13,0,0,20,0,10,0,"COL8A1;collagen, type VIII, alpha 1",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0043231//intracellular membrane-bounded organelle;GO:0005591//collagen type VIII trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen,GO:0050673//epithelial cell proliferation;GO:0001525//angiogenesis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0035987//endodermal cell differentiation;GO:0007155//cell adhesion;GO:0048593//camera-type eye morphogenesis;GO:0030574//collagen catabolic process,-,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
129521,0,0,0,0,0,0,0,0,2,0,0,0,NMS;neuromedin S,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway,-,-
129530,0,0,0,0,0,0,0,0,30,0,0,0,LYG1;lysozyme G-like 1,GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process;GO:0009253//peptidoglycan catabolic process,GO:0003796//lysozyme activity,-
129531,0,0,0,0,0,0,14,0,0,0,0,0,"MITD1;MIT, microtubule interacting and transport, domain containing 1",GO:0030496//midbody;GO:0070062//extracellular vesicular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0019898//extrinsic component of membrane;GO:0031902//late endosome membrane,GO:0071985//multivesicular body sorting pathway;GO:0032091//negative regulation of protein binding;GO:1902409//mitotic cytokinetic cell separation;GO:0000281//mitotic cytokinesis;GO:0039702//viral budding via host ESCRT complex,GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding,K12196//Endocytosis
129563,1,0,0,0,11,0,17,0,87,0,0,0,DIS3L2;DIS3 like 3'-5' exoribonuclease 2,GO:0005844//polysome;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body,"GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:1990074//polyuridylation-dependent mRNA catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0034427//nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5';GO:0019827//stem cell maintenance;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0051306//mitotic sister chromatid separation;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0010587//miRNA catabolic process;GO:0007067//mitotic nuclear division",GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0004540//ribonuclease activity;GO:0003723//RNA binding,K12585//RNA degradation
1296,0,0,0,0,0,0,0,0,44,0,17,0,"COL8A2;collagen, type VIII, alpha 2",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005581//collagen trimer;GO:0005604//basement membrane;GO:0005576//extracellular region,GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0001525//angiogenesis;GO:0050673//epithelial cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0048593//camera-type eye morphogenesis,"GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent",K07296//PPAR signaling pathway;Adipocytokine signaling pathway;Type II diabetes mellitus
129607,0,0,0,0,0,18,13,0,0,95,0,0,"CMPK2;cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006233//dTDP biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0006227//dUDP biosynthetic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation,GO:0033862//UMP kinase activity;GO:0004798//thymidylate kinase activity;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding,K13809//Pyrimidine metabolism;Metabolic pathways
129642,0,0,0,41,85,0,64,0,0,0,0,0,MBOAT2;membrane bound O-acyltransferase domain containing 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0044281//small molecule metabolic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13517//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism
129684,0,0,0,0,0,10,24,0,38,0,2,0,CNTNAP5;contactin associated protein-like 5,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,K07380//Cell adhesion molecules (CAMs)
129685,0,22,0,0,35,0,31,0,40,153,20,0,"TAF8;TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex,"GO:0045598//regulation of fat cell differentiation;GO:0001833//inner cell mass cell proliferation;GO:0051457//maintenance of protein location in nucleus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation",GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K14649//Basal transcription factors
1297,0,8,0,15,0,16,40,24,17,43,5,0,"COL9A1;collagen, type IX, alpha 1",GO:0005788//endoplasmic reticulum lumen;GO:0005594//collagen type IX trimer;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0001894//tissue homeostasis;GO:0030574//collagen catabolic process;GO:0007411//axon guidance;GO:0003417//growth plate cartilage development;GO:0009887//organ morphogenesis,GO:0046872//metal ion binding;GO:0030020//extracellular matrix structural constituent conferring tensile strength,K08131//Protein digestion and absorption
129787,0,0,0,7,31,14,0,0,26,0,25,0,TMEM18;transmembrane protein 18,GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane,"GO:0016477//cell migration;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
129790,0,0,0,0,0,0,0,18,21,0,0,0,C7orf13;chromosome 7 open reading frame 13,GO:0016021//integral component of membrane,-,-,-
1298,96,0,0,15,0,18,43,63,0,49,9,7,"COL9A2;collagen, type IX, alpha 2",GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005578//proteinaceous extracellular matrix;GO:0005594//collagen type IX trimer,GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization;GO:0007411//axon guidance,GO:0030020//extracellular matrix structural constituent conferring tensile strength,K08131//Protein digestion and absorption
129804,0,0,0,0,0,8,11,0,44,0,5,0,FBLN7;fibulin 7,GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion,GO:0008201//heparin binding;GO:0005509//calcium ion binding,K08023//TGF-beta signaling pathway;K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
129807,0,0,0,3,0,1,0,0,26,0,0,175,NEU4;sialidase 4,GO:0005764//lysosome;GO:0019866//organelle inner membrane;GO:0043202//lysosomal lumen;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0006689//ganglioside catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006516//glycoprotein catabolic process;GO:0009313//oligosaccharide catabolic process;GO:0006665//sphingolipid metabolic process,GO:0052795//exo-alpha-(2->6)-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0005515//protein binding;GO:0052796//exo-alpha-(2->8)-sialidase activity,K12357//Sphingolipid metabolism;Other glycan degradation
129831,0,12,0,0,22,0,0,0,45,0,0,0,RBM45;RNA binding motif protein 45,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007399//nervous system development;GO:0030154//cell differentiation,GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
129852,1,0,0,0,0,22,52,0,18,0,0,0,C2orf73;chromosome 2 open reading frame 73,-,-,-,-
129868,0,0,0,0,0,0,17,0,13,0,0,0,TRIM43;tripartite motif containing 43,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
129880,91,0,0,6,0,11,0,24,0,0,0,0,BBS5;Bardet-Biedl syndrome 5,GO:0036064//ciliary basal body;GO:0034464//BBSome;GO:0005622//intracellular;GO:0060170//ciliary membrane;GO:0005737//cytoplasm,GO:0001947//heart looping;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0015031//protein transport;GO:0044458//motile cilium assembly;GO:0032402//melanosome transport;GO:0050896//response to stimulus,GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0001103//RNA polymerase II repressing transcription factor binding,-
129881,0,0,0,0,0,7,23,0,79,0,0,0,CCDC173;coiled-coil domain containing 173,-,-,-,-
1299,0,0,0,14,17,0,0,24,0,0,14,0,"COL9A3;collagen, type IX, alpha 3",GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005594//collagen type IX trimer;GO:0005578//proteinaceous extracellular matrix,GO:0008584//male gonad development;GO:0007411//axon guidance;GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0008585//female gonad development;GO:0030198//extracellular matrix organization,GO:0030020//extracellular matrix structural constituent conferring tensile strength,K08131//Protein digestion and absorption
13,0,0,0,0,0,20,0,0,0,0,0,0,AADAC;arylacetamide deacetylase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0010898//positive regulation of triglyceride catabolic process;GO:0008152//metabolic process,GO:0016298//lipase activity;GO:0004806//triglyceride lipase activity;GO:0019213//deacetylase activity;GO:0017171//serine hydrolase activity;GO:0003824//catalytic activity,-
130,0,0,0,0,0,2,0,0,19,0,0,1,ADH6;alcohol dehydrogenase 6 (class V),GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006069//ethanol oxidation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0045471//response to ethanol,"GO:0035276//ethanol binding;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0008270//zinc ion binding;GO:0004024//alcohol dehydrogenase activity, zinc-dependent",K13952//Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Fatty acid metabolism;Glycolysis / Gluconeogenesis;Drug metabolism - cytochrome P450;Metabolic pathways;Tyrosine metabolism
1300,0,0,1,0,0,0,0,0,18,0,1,0,"COL10A1;collagen, type X, alpha 1",GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer;GO:0005938//cell cortex;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0051216//cartilage development;GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization;GO:0001958//endochondral ossification;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process,GO:0046872//metal ion binding,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
130013,0,2,7,15,69,18,0,0,61,0,45,0,ACMSD;aminocarboxymuconate semialdehyde decarboxylase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0046874//quinolinate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006569//tryptophan catabolic process,GO:0001760//aminocarboxymuconate-semialdehyde decarboxylase activity;GO:0046872//metal ion binding,K03392//Tryptophan metabolism;Metabolic pathways
130026,0,1,0,8,20,49,81,0,32,212,15,0,"ICA1L;islet cell autoantigen 1,69kDa-like",-,-,GO:0019904//protein domain specific binding,K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K11001//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
130074,0,109,2,34,249,0,27,0,11,0,12,0,"FAM168B;family with sequence similarity 168, member B",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030424//axon;GO:0048471//perinuclear region of cytoplasm,-,-,-
130075,0,0,0,0,0,0,0,42,6,0,0,0,"OR9A4;olfactory receptor, family 9, subfamily A, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1301,0,0,0,7,0,18,19,0,65,0,11,0,"COL11A1;collagen, type XI, alpha 1",GO:0005592//collagen type XI trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0035987//endodermal cell differentiation;GO:0048704//embryonic skeletal system morphogenesis;GO:0001502//cartilage condensation;GO:0002063//chondrocyte development;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0030574//collagen catabolic process;GO:0030199//collagen fibril organization;GO:0007601//visual perception;GO:0006029//proteoglycan metabolic process;GO:0007605//sensory perception of sound;GO:0022617//extracellular matrix disassembly;GO:0042472//inner ear morphogenesis;GO:0030198//extracellular matrix organization,"GO:0050840//extracellular matrix binding;GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent;GO:0030674//protein binding, bridging",K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
130106,0,0,0,0,0,11,25,50,11,58,0,0,CIB4;calcium and integrin binding family member 4,-,-,GO:0005509//calcium ion binding,K06268//Alzheimer's disease;Osteoclast differentiation;VEGF signaling pathway;HTLV-I infection;B cell receptor signaling pathway;Calcium signaling pathway;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;Apoptosis;T cell receptor signaling pathway;Glutamatergic synapse;Amphetamine addiction;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Axon guidance;Long-term potentiation;Tuberculosis
130120,0,0,0,0,6,0,0,0,0,0,0,0,REG3G;regenerating islet-derived 3 gamma,GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0090303//positive regulation of wound healing;GO:0050830//defense response to Gram-positive bacterium;GO:0010838//positive regulation of keratinocyte proliferation;GO:0006953//acute-phase response;GO:0045617//negative regulation of keratinocyte differentiation,GO:0030246//carbohydrate binding,K06560//Phagosome;Tuberculosis
130132,0,0,0,0,0,13,7,0,28,0,33,0,RFTN2;raftlin family member 2,GO:0005886//plasma membrane,GO:0043330//response to exogenous dsRNA;GO:0033227//dsRNA transport,-,-
130162,0,0,0,0,16,0,0,0,55,0,0,0,CLHC1;clathrin heavy chain linker domain containing 1,-,-,-,K04646//Bacterial invasion of epithelial cells;Endocytosis;Huntington's disease;Lysosome;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
1302,0,0,0,0,0,0,0,0,3,0,0,0,"COL11A2;collagen, type XI, alpha 2",GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005592//collagen type XI trimer,GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0007605//sensory perception of sound;GO:0051216//cartilage development;GO:0001501//skeletal system development;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process;GO:0060021//palate development;GO:0060023//soft palate development,"GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030674//protein binding, bridging;GO:0030020//extracellular matrix structural constituent conferring tensile strength",K06236//Protein digestion and absorption;Amoebiasis;Focal adhesion;ECM-receptor interaction
130271,0,0,0,0,8,23,17,0,70,99,7,0,"PLEKHH2;pleckstrin homology domain containing, family H (with MyTH4 domain) member 2",GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0030864//cortical actin cytoskeleton,GO:0030835//negative regulation of actin filament depolymerization,GO:0003779//actin binding;GO:0042802//identical protein binding,K12559//Fc gamma R-mediated phagocytosis
1303,149,0,0,0,0,51,158,0,154,0,2,214,"COL12A1;collagen, type XII, alpha 1",GO:0005576//extracellular region;GO:0005595//collagen type XII trimer;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0031982//vesicle;GO:0005788//endoplasmic reticulum lumen,GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation;GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030199//collagen fibril organization;GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development,GO:0030020//extracellular matrix structural constituent conferring tensile strength,K08132//Protein digestion and absorption
130340,0,1,0,10,16,17,24,0,0,0,0,0,"AP1S3;adaptor-related protein complex 1, sigma 3 subunit",GO:0005905//coated pit;GO:0005765//lysosomal membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030117//membrane coat;GO:0032588//trans-Golgi network membrane,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006892//post-Golgi vesicle-mediated transport;GO:0016032//viral process;GO:0061024//membrane organization;GO:0050690//regulation of defense response to virus by virus;GO:0006886//intracellular protein transport,GO:0008565//protein transporter activity,K12395//Lysosome
130355,0,1,0,9,63,0,0,0,43,0,0,0,C2orf76;chromosome 2 open reading frame 76,-,-,-,-
130367,0,0,0,0,0,0,0,0,0,0,12,0,SGPP2;sphingosine-1-phosphate phosphatase 2,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0016311//dephosphorylation;GO:0006665//sphingolipid metabolic process;GO:0006670//sphingosine metabolic process,GO:0042392//sphingosine-1-phosphate phosphatase activity,K04717//Sphingolipid metabolism
130399,0,0,0,0,0,13,0,0,70,0,9,0,"ACVR1C;activin A receptor, type IC",GO:0005886//plasma membrane;GO:0048179//activin receptor complex,GO:0038092//nodal signaling pathway;GO:0030262//apoptotic nuclear changes;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002021//response to dietary excess;GO:0019915//lipid storage;GO:0006468//protein phosphorylation;GO:0046676//negative regulation of insulin secretion;GO:0009749//response to glucose;GO:0030154//cell differentiation;GO:1901164//negative regulation of trophoblast cell migration;GO:0032868//response to insulin;GO:0023014//signal transduction by phosphorylation;GO:1901383//negative regulation of chorionic trophoblast cell proliferation,"GO:0046872//metal ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0019838//growth factor binding;GO:0016361//activin receptor activity, type I;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005524//ATP binding;GO:0038100//nodal binding",K13568//TGF-beta signaling pathway
130497,0,0,0,0,0,0,0,0,32,0,0,0,OSR1;odd-skipped related transciption factor 1,GO:0005634//nucleus,"GO:0072239//metanephric glomerulus vasculature development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001823//mesonephros development;GO:0072190//ureter urothelium development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//palate development;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0048389//intermediate mesoderm development;GO:0007507//heart development;GO:0035116//embryonic hindlimb morphogenesis;GO:0008406//gonad development;GO:0048863//stem cell differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0048793//pronephros development;GO:0072166//posterior mesonephric tubule development;GO:0042474//middle ear morphogenesis;GO:0072143//mesangial cell development;GO:2000543//positive regulation of gastrulation;GO:0030501//positive regulation of bone mineralization;GO:0072184//renal vesicle progenitor cell differentiation;GO:0072207//metanephric epithelium development;GO:0072234//metanephric nephron tubule development;GO:0042733//embryonic digit morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002062//chondrocyte differentiation;GO:0072162//metanephric mesenchymal cell differentiation;GO:0072183//negative regulation of nephron tubule epithelial cell differentiation;GO:0072075//metanephric mesenchyme development;GO:0072169//specification of posterior mesonephric tubule identity;GO:0072133//metanephric mesenchyme morphogenesis;GO:0072498//embryonic skeletal joint development;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0090094//metanephric cap mesenchymal cell proliferation involved in metanephros development;GO:0072180//mesonephric duct morphogenesis;GO:0072208//metanephric smooth muscle tissue development;GO:0072259//metanephric interstitial fibroblast development;GO:0030154//cell differentiation;GO:0042476//odontogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072168//specification of anterior mesonephric tubule identity;GO:0001655//urogenital system development;GO:0001657//ureteric bud development;GO:0030857//negative regulation of epithelial cell differentiation;GO:0072268//pattern specification involved in metanephros development",GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
1305,50,0,0,0,0,14,51,0,86,0,0,0,"COL13A1;collagen, type XIII, alpha 1",GO:0005788//endoplasmic reticulum lumen;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0016337//single organismal cell-cell adhesion;GO:0001763//morphogenesis of a branching structure;GO:0007160//cell-matrix adhesion;GO:0030574//collagen catabolic process;GO:0001958//endochondral ossification;GO:0030198//extracellular matrix organization;GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly,GO:0005515//protein binding;GO:0008201//heparin binding,K06237//Pathways in cancer;ECM-receptor interaction;Small cell lung cancer;Amoebiasis;Protein digestion and absorption;Focal adhesion
130502,0,0,1,8,20,0,0,0,0,0,0,0,TTC32;tetratricopeptide repeat domain 32,-,-,GO:0042802//identical protein binding,-
130507,34,97,0,30,105,24,0,0,91,0,0,1,UBR3;ubiquitin protein ligase E3 component n-recognin 3 (putative),GO:0016021//integral component of membrane,GO:0001701//in utero embryonic development;GO:0009790//embryo development;GO:0007608//sensory perception of smell;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001967//suckling behavior;GO:0042048//olfactory behavior;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
130535,0,0,0,0,48,0,6,0,49,0,0,27,KCTD18;potassium channel tetramerization domain containing 18,-,GO:0051260//protein homooligomerization,-,-
130540,0,0,0,0,0,16,8,0,0,0,0,0,"ALS2CR12;amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12",GO:0001520//outer dense fiber;GO:0035686//sperm fibrous sheath;GO:0036126//sperm flagellum,GO:0043087//regulation of GTPase activity,GO:0005515//protein binding,-
130557,178,0,0,0,3,0,0,0,21,0,0,0,ZNF513;zinc finger protein 513,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0060041//retina development in camera-type eye;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0006355//regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
130560,184,0,0,0,0,0,0,0,0,0,1,0,SPATA3;spermatogenesis associated 3,-,-,-,-
130574,0,0,0,0,1,0,20,0,44,75,0,0,LYPD6;LY6/PLAUR domain containing 6,GO:0005576//extracellular region,-,-,-
130576,60,0,0,0,0,14,31,20,18,0,0,1,LYPD6B;LY6/PLAUR domain containing 6B,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,-,-,-
130589,0,0,0,0,18,0,0,51,17,0,10,0,GALM;galactose mutarotase (aldose 1-epimerase),GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006012//galactose metabolic process;GO:0006006//glucose metabolic process,GO:0030246//carbohydrate binding;GO:0004034//aldose 1-epimerase activity,K01785//Homologous recombination;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments
1306,0,0,0,0,0,23,30,1,46,22,5,218,"COL15A1;collagen, type XV, alpha 1",GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005582//collagen type XV trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen,GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030574//collagen catabolic process;GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly,GO:0005201//extracellular matrix structural constituent,K08135//Protein digestion and absorption
130612,0,2,0,0,1,2,0,0,3,0,4,0,TMEM198;transmembrane protein 198,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0007275//multicellular organismal development;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway,-,-
130617,0,0,0,0,0,0,0,0,7,0,0,0,"ZFAND2B;zinc finger, AN1-type domain 2B",GO:0005783//endoplasmic reticulum,-,GO:0005515//protein binding;GO:0008270//zinc ion binding,-
1307,34,0,0,0,0,29,173,180,113,70,10,0,"COL16A1;collagen, type XVI, alpha 1",GO:0005788//endoplasmic reticulum lumen;GO:0005578//proteinaceous extracellular matrix;GO:0005597//collagen type XVI trimer;GO:0005576//extracellular region,GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007565//female pregnancy;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization;GO:0071230//cellular response to amino acid stimulus,GO:0005515//protein binding;GO:0005178//integrin binding,K08131//Protein digestion and absorption
130749,0,0,0,0,0,0,0,0,12,0,0,0,CPO;carboxypeptidase O,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,K01291//Protein digestion and absorption;Pancreatic secretion;K01300//Pancreatic secretion;Protein digestion and absorption;Complement and coagulation cascades
130752,0,0,0,0,0,17,0,108,30,0,0,0,"MDH1B;malate dehydrogenase 1B, NAD (soluble)",-,GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006108//malate metabolic process,"GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016615//malate dehydrogenase activity",K00025//Citrate cycle (TCA cycle);Metabolic pathways;Pyruvate metabolism;Glyoxylate and dicarboxylate metabolism;Carbon fixation in photosynthetic organisms;Proximal tubule bicarbonate reclamation;Biosynthesis of secondary metabolites
1308,385,0,0,0,0,7,32,0,139,140,32,0,"COL17A1;collagen, type XVII, alpha 1",GO:0005911//cell-cell junction;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005581//collagen trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005887//integral component of plasma membrane;GO:0005604//basement membrane;GO:0030056//hemidesmosome,GO:0034329//cell junction assembly;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0007160//cell-matrix adhesion;GO:0031581//hemidesmosome assembly;GO:0030198//extracellular matrix organization;GO:0008544//epidermis development,GO:0005515//protein binding,K07603//Protein digestion and absorption
130813,0,0,0,0,0,0,0,0,17,0,0,0,C2orf50;chromosome 2 open reading frame 50,-,-,-,-
130814,0,0,0,1,0,0,18,0,34,0,0,0,PQLC3;PQ loop repeat containing 3,GO:0016021//integral component of membrane,-,-,-
130827,0,0,0,8,0,1,0,0,0,0,16,0,TMEM182;transmembrane protein 182,GO:0016021//integral component of membrane,-,-,-
130872,4,0,0,30,31,25,0,0,0,0,19,0,"AHSA2;AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)",-,GO:0006950//response to stress;GO:0032781//positive regulation of ATPase activity,GO:0001671//ATPase activator activity;GO:0051087//chaperone binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K14443//RNA degradation;K11447//Transcriptional misregulation in cancer
130888,0,0,0,0,0,4,18,53,0,0,0,0,FBXO36;F-box protein 36,-,-,-,-
130916,0,27,0,5,24,0,11,0,0,0,18,1,MTERF4;mitochondrial transcription termination factor 4,GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005762//mitochondrial large ribosomal subunit,GO:0006364//rRNA processing,GO:0005515//protein binding;GO:0019843//rRNA binding,-
130951,0,0,0,0,0,0,0,13,11,174,6,0,M1AP;meiosis 1 associated protein,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0006396//RNA processing;GO:0030154//cell differentiation;GO:0007292//female gamete generation;GO:0051308//male meiosis chromosome separation;GO:0007283//spermatogenesis;GO:0031497//chromatin assembly,-,K03956//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
131,0,0,0,0,0,0,0,0,0,1,0,0,"ADH7;alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide",GO:0005576//extracellular region;GO:0005829//cytosol,GO:0045471//response to ethanol;GO:0010430//fatty acid omega-oxidation;GO:0055114//oxidation-reduction process;GO:0006069//ethanol oxidation;GO:0006068//ethanol catabolic process;GO:0006805//xenobiotic metabolic process;GO:0042573//retinoic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0009617//response to bacterium;GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:1900116//extracellular negative regulation of signal transduction,"GO:0004024//alcohol dehydrogenase activity, zinc-dependent;GO:0004031//aldehyde oxidase activity;GO:0004745//retinol dehydrogenase activity;GO:0019841//retinol binding;GO:0008270//zinc ion binding;GO:0035276//ethanol binding;GO:0004022//alcohol dehydrogenase (NAD) activity;GO:0048019//receptor antagonist activity",K13951//Tyrosine metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Fatty acid metabolism;Glycolysis / Gluconeogenesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism
1310,70,0,0,0,0,38,79,0,85,20,20,0,"COL19A1;collagen, type XIX, alpha 1",GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005581//collagen trimer,GO:0016337//single organismal cell-cell adhesion;GO:0007155//cell adhesion;GO:0001501//skeletal system development;GO:0030574//collagen catabolic process;GO:0007519//skeletal muscle tissue development;GO:0030198//extracellular matrix organization;GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly,"GO:0030674//protein binding, bridging;GO:0005201//extracellular matrix structural constituent",K08132//Protein digestion and absorption
131034,34,117,2,69,166,60,10,1,44,13,11,0,CPNE4;copine IV,GO:0070062//extracellular vesicular exosome,-,-,K02677//VEGF signaling pathway;Focal adhesion;Pathogenic Escherichia coli infection;Glioma;Gastric acid secretion;Leishmaniasis;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Calcium signaling pathway;Retrograde endocannabinoid signaling;Long-term depression;ErbB signaling pathway;Morphine addiction;MAPK signaling pathway;Influenza A;Serotonergic synapse;NF-kappa B signaling pathway;Gap junction;Dopaminergic synapse;Chemokine signaling pathway;GnRH signaling pathway;Pathways in cancer;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;B cell receptor signaling pathway;Salivary secretion;Fc epsilon RI signaling pathway;Cholinergic synapse;Tight junction;GABAergic synapse;Amoebiasis;Phototransduction - fly;Vascular smooth muscle contraction;Wnt signaling pathway;Natural killer cell mediated cytotoxicity;Amphetamine addiction;Glutamatergic synapse;Carbohydrate digestion and absorption;Long-term potentiation;African trypanosomiasis;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;MAPK signaling pathway - yeast;Phosphatidylinositol signaling system;K06491//Cell adhesion molecules (CAMs);Prion diseases
131076,0,0,0,0,1,0,0,0,1,0,0,0,CCDC58;coiled-coil domain containing 58,GO:0005739//mitochondrion,-,-,-
131096,3,0,0,23,0,15,18,0,21,0,8,0,"KCNH8;potassium voltage-gated channel, subfamily H (eag-related), member 8",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0023014//signal transduction by phosphorylation;GO:0071805//potassium ion transmembrane transport;GO:0000160//phosphorelay signal transduction system;GO:0042391//regulation of membrane potential,GO:0005249//voltage-gated potassium channel activity;GO:0000155//phosphorelay sensor kinase activity,-
1311,0,0,0,0,0,14,36,0,4,0,10,0,COMP;cartilage oligomeric matrix protein,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0003417//growth plate cartilage development;GO:0009887//organ morphogenesis;GO:0007155//cell adhesion;GO:0043066//negative regulation of apoptotic process;GO:0001501//skeletal system development;GO:0006915//apoptotic process;GO:0060173//limb development;GO:0030198//extracellular matrix organization,GO:0005518//collagen binding;GO:0002020//protease binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0008201//heparin binding;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005509//calcium ion binding,K04659//Focal adhesion;TGF-beta signaling pathway;Bladder cancer;p53 signaling pathway;Phagosome;ECM-receptor interaction;Malaria
131118,1,0,0,8,26,0,0,0,0,0,1,0,"DNAJC19;DnaJ (Hsp40) homolog, subfamily C, member 19",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006626//protein targeting to mitochondrion;GO:0048806//genitalia development;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process;GO:0007601//visual perception,-,-
131149,0,0,0,0,0,0,0,0,17,0,0,0,OTOL1;otolin 1,GO:0005581//collagen trimer;GO:0005576//extracellular region,-,-,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
131177,54,0,0,0,0,0,0,83,24,0,0,0,"FAM3D;family with sequence similarity 3, member D",GO:0005576//extracellular region,GO:0046676//negative regulation of insulin secretion,GO:0005125//cytokine activity,K09666//Other types of O-glycan biosynthesis
1312,0,59,0,11,0,0,0,115,46,0,77,0,COMT;catechol-O-methyltransferase,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0014070//response to organic cyclic compound;GO:0050668//positive regulation of homocysteine metabolic process;GO:0008210//estrogen metabolic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0042420//dopamine catabolic process;GO:0007268//synaptic transmission;GO:0048265//response to pain;GO:0045963//negative regulation of dopamine metabolic process;GO:0048609//multicellular organismal reproductive process;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0032259//methylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0042135//neurotransmitter catabolic process;GO:0007612//learning,GO:0008171//O-methyltransferase activity;GO:0016206//catechol O-methyltransferase activity;GO:0000287//magnesium ion binding,K00545//Dopaminergic synapse;Metabolic pathways;Tyrosine metabolism;Betalain biosynthesis;Steroid hormone biosynthesis
131368,0,0,0,0,0,1,0,0,24,0,0,0,ZPLD1;zona pellucida-like domain containing 1,GO:0016021//integral component of membrane,-,-,K13912//Salivary secretion
131375,0,0,0,0,0,0,33,38,0,0,0,0,LYZL4;lysozyme-like 4,GO:0005634//nucleus;GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process,GO:0003796//lysozyme activity,-
131377,7,0,0,0,0,0,4,0,0,0,8,0,KLHL40;kelch-like family member 40,GO:0031672//A band,GO:0007275//multicellular organismal development,-,-
1314,68,61,5,71,244,0,24,0,142,0,42,0,"COPA;coatomer protein complex, subunit alpha",GO:0005737//cytoplasm;GO:0030126//COPI vesicle coat;GO:0016020//membrane;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,"GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0061024//membrane organization;GO:0048205//COPI coating of Golgi vesicle;GO:0030157//pancreatic juice secretion",GO:0005198//structural molecule activity;GO:0005179//hormone activity,-
131405,0,0,0,0,0,0,0,0,3,0,0,334,"TRIM71;tripartite motif containing 71, E3 ubiquitin protein ligase",GO:0000932//cytoplasmic mRNA processing body,GO:0010586//miRNA metabolic process;GO:0001843//neural tube closure;GO:2000637//positive regulation of gene silencing by miRNA;GO:0060964//regulation of gene silencing by miRNA;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0072089//stem cell proliferation;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:2000177//regulation of neural precursor cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0021915//neural tube development;GO:0051865//protein autoubiquitination,GO:0035198//miRNA binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
131408,116,0,0,0,0,0,0,0,27,87,3,0,"FAM131A;family with sequence similarity 131, member A",GO:0005576//extracellular region,-,-,-
131450,0,0,0,0,0,0,0,0,22,0,0,0,CD200R1;CD200 receptor 1,GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0050776//regulation of immune response;GO:0016032//viral process,GO:0005515//protein binding,-
131474,0,19,2,4,46,21,0,0,50,0,0,0,CHCHD4;coiled-coil-helix-coiled-coil-helix domain containing 4,GO:0005758//mitochondrial intermembrane space,GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion;GO:0055114//oxidation-reduction process;GO:0045041//protein import into mitochondrial intermembrane space;GO:0022417//protein maturation by protein folding;GO:0051084//'de novo' posttranslational protein folding,GO:0015035//protein disulfide oxidoreductase activity,K14529//RNA transport
1315,0,17,0,12,122,15,32,0,7,0,1,0,"COPB1;coatomer protein complex, subunit beta 1",GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0030126//COPI vesicle coat;GO:0005798//Golgi-associated vesicle;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0061024//membrane organization;GO:0016032//viral process;GO:0048205//COPI coating of Golgi vesicle",GO:0005515//protein binding;GO:0005198//structural molecule activity,K12396//Lysosome;K12392//Lysosome
131540,0,0,0,0,0,0,23,0,18,0,0,0,"ZDHHC19;zinc finger, DHHC-type containing 19",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0008270//zinc ion binding,K05766//Regulation of actin cytoskeleton
131544,0,385,132,670,1121,29,34,50,60,0,115,0,CRYBG3;beta-gamma crystallin domain containing 3,-,-,GO:0030246//carbohydrate binding,-
131566,0,0,0,16,22,0,38,3,25,0,11,0,"DCBLD2;discoidin, CUB and LCCL domain containing 2",GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0030308//negative regulation of cell growth;GO:0007155//cell adhesion;GO:0042060//wound healing;GO:0030522//intracellular receptor signaling pathway,GO:0005515//protein binding,K03902//Complement and coagulation cascades
131578,0,0,0,0,0,47,31,0,7,157,0,0,LRRC15;leucine rich repeat containing 15,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0030335//positive regulation of cell migration;GO:0046813//receptor-mediated virion attachment to host cell,GO:0043236//laminin binding;GO:0005518//collagen binding;GO:0001968//fibronectin binding,K06260//ECM-receptor interaction;Hematopoietic cell lineage
131583,0,0,0,4,0,43,18,1,14,2,16,0,"FAM43A;family with sequence similarity 43, member A",-,-,-,K12474//Endocytosis
1316,0,0,0,6,22,1,0,0,10,0,9,0,KLF6;Kruppel-like factor 6,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0030183//B cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0019221//cytokine-mediated signaling pathway",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
131601,0,0,0,0,0,0,16,0,11,0,0,0,"TPRA1;transmembrane protein, adipocyte asscociated 1",GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0006629//lipid metabolic process;GO:0007568//aging,GO:0004930//G-protein coupled receptor activity,-
131616,0,0,0,0,0,3,0,0,0,0,0,0,TMEM42;transmembrane protein 42,GO:0016021//integral component of membrane,-,-,-
131669,35,0,0,0,0,11,0,0,14,0,3,7,UROC1;urocanate hydratase 1,GO:0005829//cytosol,GO:0019556//histidine catabolic process to glutamate and formamide;GO:0034641//cellular nitrogen compound metabolic process;GO:0019557//histidine catabolic process to glutamate and formate;GO:0044281//small molecule metabolic process;GO:0006548//histidine catabolic process,GO:0016153//urocanate hydratase activity,K01712//Metabolic pathways;Histidine metabolism
1317,104,1,0,37,41,1,39,0,35,0,0,0,"SLC31A1;solute carrier family 31 (copper transporter), member 1",GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0055037//recycling endosome,GO:0006878//cellular copper ion homeostasis;GO:0035434//copper ion transmembrane transport;GO:0015677//copper ion import;GO:0006825//copper ion transport;GO:0055085//transmembrane transport,GO:0005375//copper ion transmembrane transporter activity,K14686//Mineral absorption
1318,0,0,0,9,29,0,0,0,16,0,19,0,"SLC31A2;solute carrier family 31 (copper transporter), member 2",GO:0005770//late endosome;GO:0005887//integral component of plasma membrane;GO:0055037//recycling endosome,GO:0006825//copper ion transport;GO:0035434//copper ion transmembrane transport;GO:0006878//cellular copper ion homeostasis,GO:0005375//copper ion transmembrane transporter activity,-
131831,0,125,0,27,48,0,48,0,21,0,11,28,ERICH6;glutamate-rich 6,-,-,-,-
131870,0,2,0,8,99,17,8,0,29,0,0,0,NUDT16;nudix (nucleoside diphosphate linked moiety X)-type motif 16,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0090068//positive regulation of cell cycle process;GO:2000781//positive regulation of double-strand break repair;GO:0046709//IDP catabolic process;GO:0044281//small molecule metabolic process;GO:0006382//adenosine to inosine editing;GO:0008284//positive regulation of cell proliferation;GO:0016077//snoRNA catabolic process;GO:2000233//negative regulation of rRNA processing;GO:1901639//XDP catabolic process;GO:0006402//mRNA catabolic process;GO:0006508//proteolysis;GO:0035863//dITP catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0016311//dephosphorylation,"GO:0003729//mRNA binding;GO:0030145//manganese ion binding;GO:0035870//dITP diphosphatase activity;GO:1901640//XTP binding;GO:0005525//GTP binding;GO:0030515//snoRNA binding;GO:0050897//cobalt ion binding;GO:0097383//dIDP diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0000287//magnesium ion binding;GO:1901641//ITP binding;GO:0008235//metalloexopeptidase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:0090450//inosine-diphosphatase activity",K01529//Purine metabolism
131873,0,0,0,0,2,1,86,114,116,39,0,0,"COL6A6;collagen, type VI, alpha 6",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005581//collagen trimer;GO:0005576//extracellular region,GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion,-,K06238//ECM-receptor interaction;Protein digestion and absorption;Focal adhesion
131890,0,0,0,0,0,0,9,0,0,0,0,0,GRK7;G protein-coupled receptor kinase 7,GO:0016020//membrane,GO:0007601//visual perception;GO:0007165//signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0046777//protein autophosphorylation,GO:0050254//rhodopsin kinase activity;GO:0005524//ATP binding;GO:0004703//G-protein coupled receptor kinase activity,K00909//Endocytosis;Phototransduction;Chemokine signaling pathway
131909,95,0,0,0,0,0,0,0,1,0,7,0,"FAM172BP;family with sequence similarity 172, member B pseudogene",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
131920,0,0,0,0,0,0,0,0,0,0,0,662,TMEM207;transmembrane protein 207,GO:0016021//integral component of membrane,-,-,K04723//Apoptosis;Cytokine-cytokine receptor interaction
132,0,0,1,0,12,5,0,0,73,0,0,0,ADK;adenosine kinase,GO:0005634//nucleus;GO:0005829//cytosol,GO:0046085//adenosine metabolic process;GO:0042102//positive regulation of T cell proliferation;GO:0016310//phosphorylation;GO:0043101//purine-containing compound salvage;GO:0044281//small molecule metabolic process;GO:0044342//type B pancreatic cell proliferation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0032922//circadian regulation of gene expression;GO:0006175//dATP biosynthetic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0044209//AMP salvage,"GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0004001//adenosine kinase activity;GO:0005524//ATP binding",K00856//Metabolic pathways;Purine metabolism
132001,0,0,0,0,0,53,0,0,7,0,0,0,"TAMM41;TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)",GO:0031314//extrinsic component of mitochondrial inner membrane,GO:0032049//cardiolipin biosynthetic process;GO:0015031//protein transport,GO:0004605//phosphatidate cytidylyltransferase activity,-
132014,0,0,0,0,0,8,0,0,33,0,12,0,IL17RE;interleukin 17 receptor E,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0006954//inflammatory response,GO:0005515//protein binding,-
132112,0,0,0,0,0,0,0,0,15,0,4,0,RTP1;receptor (chemosensory) transporter protein 1,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0051205//protein insertion into membrane,GO:0031849//olfactory receptor binding,-
132141,0,0,0,0,0,0,0,0,18,0,0,0,IQCF1;IQ motif containing F1,-,-,-,-
132158,0,29,0,0,0,0,20,0,31,0,23,0,GLYCTK;glycerate kinase,GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008887//glycerate kinase activity,"K15788//Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Glycerolipid metabolism;Glycine, serine and threonine metabolism"
132160,0,2,1,1,8,0,0,6,43,122,0,0,"PPM1M;protein phosphatase, Mg2+/Mn2+ dependent, 1M",GO:0005634//nucleus,GO:0006470//protein dephosphorylation,GO:0030145//manganese ion binding;GO:0008420//CTD phosphatase activity,-
132200,0,0,0,0,0,0,0,0,0,0,17,0,C3orf49;chromosome 3 open reading frame 49,-,-,-,-
132203,0,0,0,0,0,0,0,0,13,0,0,0,"SNTN;sentan, cilia apical structure protein",GO:0005929//cilium,-,GO:0005509//calcium ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion
132204,0,0,0,0,0,3,52,0,72,0,0,0,SYNPR;synaptoporin,GO:0030285//integral component of synaptic vesicle membrane;GO:0030054//cell junction;GO:0043005//neuron projection,GO:0006810//transport,GO:0005215//transporter activity,-
132228,230,288,74,131,284,3,20,37,0,0,503,0,LSMEM2;leucine-rich single-pass membrane protein 2,GO:0016021//integral component of membrane,-,-,-
132243,0,0,0,0,0,24,0,0,14,0,0,0,"H1FOO;H1 histone family, member O, oocyte-specific",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0001674//female germ cell nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,GO:2000737//negative regulation of stem cell differentiation;GO:0044030//regulation of DNA methylation;GO:0007126//meiotic nuclear division;GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning,GO:0031492//nucleosomal DNA binding,-
132299,0,0,0,5,0,12,0,0,5,0,0,0,OCIAD2;OCIA domain containing 2,GO:0005743//mitochondrial inner membrane;GO:0005768//endosome,-,-,-
132320,0,0,0,0,0,0,0,0,13,0,0,0,SCLT1;sodium channel and clathrin linker 1,GO:0015630//microtubule cytoskeleton;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0071439//clathrin complex;GO:0097539//ciliary transition fiber;GO:0070062//extracellular vesicular exosome,GO:0045162//clustering of voltage-gated sodium channels;GO:0042384//cilium assembly,GO:0030276//clathrin binding;GO:0008022//protein C-terminus binding;GO:0017080//sodium channel regulator activity,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
132321,0,21,37,0,0,0,14,1,1,0,0,0,C4orf33;chromosome 4 open reading frame 33,-,-,-,-
132332,0,0,0,0,0,0,7,0,1,0,0,0,TMEM155;transmembrane protein 155,GO:0005576//extracellular region,-,-,-
132430,0,0,0,10,29,0,17,54,2,0,2,0,"PABPC4L;poly(A) binding protein, cytoplasmic 4-like",-,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K13126//RNA degradation;RNA transport;mRNA surveillance pathway
1325,0,0,0,0,0,0,0,0,16,0,0,0,CORT;cortistatin,GO:0005615//extracellular space,GO:0007268//synaptic transmission;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0005184//neuropeptide hormone activity;GO:0001664//G-protein coupled receptor binding,-
1326,1,0,0,0,0,0,0,19,25,0,8,0,MAP3K8;mitogen-activated protein kinase kinase kinase 8,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0000186//activation of MAPKK activity;GO:0000165//MAPK cascade;GO:0031295//T cell costimulation,GO:0004709//MAP kinase kinase kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K04415//Toll-like receptor signaling pathway;MAPK signaling pathway;T cell receptor signaling pathway
132612,0,0,0,0,0,19,0,0,22,0,0,0,ADAD1;adenosine deaminase domain containing 1 (testis-specific),GO:0005634//nucleus,GO:0006396//RNA processing;GO:0007286//spermatid development;GO:0007275//multicellular organismal development,GO:0004000//adenosine deaminase activity;GO:0003723//RNA binding,K12968//Measles;Influenza A;Cytosolic DNA-sensing pathway
132625,0,0,0,0,0,0,0,15,5,0,5,0,ZFP42;ZFP42 zinc finger protein,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0007286//spermatid development;GO:0008584//male gonad development;GO:2000653//regulation of genetic imprinting;GO:0007126//meiotic nuclear division;GO:0008585//female gonad development;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding,-
132660,3,0,0,15,38,13,17,0,34,0,1,0,LIN54;lin-54 homolog (C. elegans),GO:0005654//nucleoplasm,"GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding,K10955//Amoebiasis;Vibrio cholerae infection;K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation
132671,0,0,1,10,26,0,0,0,26,0,0,0,SPATA18;spermatogenesis associated 18,GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0035695//mitochondrion degradation by induced vacuole formation;GO:0035694//mitochondrial protein catabolic process;GO:0006974//cellular response to DNA damage stimulus,GO:0005515//protein binding,-
1327,0,70,28,10,11,0,1,24,10,0,28,0,COX4I1;cytochrome c oxidase subunit IV isoform 1,GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016020//membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0007584//response to nutrient;GO:0006091//generation of precursor metabolites and energy;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,GO:0005515//protein binding;GO:0004129//cytochrome-c oxidase activity,K02263//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation;Cardiac muscle contraction
132720,139,34,0,14,45,0,17,0,3,0,0,0,C4orf32;chromosome 4 open reading frame 32,GO:0016021//integral component of membrane,-,-,-
132724,0,0,0,0,0,0,0,0,7,0,0,0,"TMPRSS11B;transmembrane protease, serine 11B",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
132789,95,0,0,4,12,0,0,1,26,0,4,0,GNPDA2;glucosamine-6-phosphate deaminase 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0005975//carbohydrate metabolic process;GO:0006044//N-acetylglucosamine metabolic process,GO:0016787//hydrolase activity;GO:0004342//glucosamine-6-phosphate deaminase activity,K02564//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Ribosome;Lipopolysaccharide biosynthesis;Two-component system;ABC transporters;Metabolic pathways
132851,37,0,0,0,0,12,0,0,0,0,0,0,SPATA4;spermatogenesis associated 4,GO:0005737//cytoplasm,-,-,-
132864,0,0,0,4,58,28,0,0,49,0,7,0,CPEB2;cytoplasmic polyadenylation element binding protein 2,GO:1990124//messenger ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:1900248//negative regulation of cytoplasmic translational elongation;GO:2000766//negative regulation of cytoplasmic translation;GO:0071456//cellular response to hypoxia;GO:0071243//cellular response to arsenic-containing substance;GO:0034260//negative regulation of GTPase activity;GO:0032869//cellular response to insulin stimulus;GO:0034599//cellular response to oxidative stress,"GO:0005095//GTPase inhibitor activity;GO:0000166//nucleotide binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0044822//poly(A) RNA binding;GO:0043023//ribosomal large subunit binding;GO:0043022//ribosome binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0043024//ribosomal small subunit binding",K02602//Progesterone-mediated oocyte maturation;Dorso-ventral axis formation;Oocyte meiosis
132884,145,0,0,0,0,0,74,1,29,0,5,0,EVC2;Ellis van Creveld syndrome 2,GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0016021//integral component of membrane;GO:0005929//cilium,GO:0007224//smoothened signaling pathway,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
1329,0,0,0,0,23,0,0,0,0,0,0,0,COX5B;cytochrome c oxidase subunit Vb,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0007585//respiratory gaseous exchange;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0004129//cytochrome-c oxidase activity,K02265//Cardiac muscle contraction;Metabolic pathways;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease
132946,0,0,0,0,0,0,0,0,7,0,0,0,ARL9;ADP-ribosylation factor-like 9,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
132949,0,1,0,0,32,40,42,0,27,0,20,0,AASDH;aminoadipate-semialdehyde dehydrogenase,-,GO:0006631//fatty acid metabolic process,GO:0005524//ATP binding;GO:0016878//acid-thiol ligase activity,-
132954,0,0,0,0,0,0,22,0,0,0,0,0,PDCL2;phosducin-like 2,-,-,-,K08327//Olfactory transduction
132989,0,0,0,1,0,0,0,0,0,0,13,0,C4orf36;chromosome 4 open reading frame 36,-,-,-,-
133,0,0,0,0,0,0,6,0,0,0,0,0,ADM;adrenomedullin,GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0008209//androgen metabolic process;GO:0009611//response to wounding;GO:0031623//receptor internalization;GO:0002026//regulation of the force of heart contraction;GO:2001214//positive regulation of vasculogenesis;GO:0097084//vascular smooth muscle cell development;GO:0048589//developmental growth;GO:0046879//hormone secretion;GO:0001843//neural tube closure;GO:0042475//odontogenesis of dentin-containing tooth;GO:0007568//aging;GO:0008285//negative regulation of cell proliferation;GO:0043116//negative regulation of vascular permeability;GO:0009409//response to cold;GO:0006171//cAMP biosynthetic process;GO:0031102//neuron projection regeneration;GO:0007507//heart development;GO:0010460//positive regulation of heart rate;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0007565//female pregnancy;GO:0002031//G-protein coupled receptor internalization;GO:0043065//positive regulation of apoptotic process;GO:0060712//spongiotrophoblast layer development;GO:0001666//response to hypoxia;GO:0007165//signal transduction;GO:0008015//blood circulation;GO:0045909//positive regulation of vasodilation;GO:0019933//cAMP-mediated signaling;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0042594//response to starvation;GO:0045906//negative regulation of vasoconstriction;GO:0032868//response to insulin;GO:0001570//vasculogenesis;GO:0051384//response to glucocorticoid;GO:0007267//cell-cell signaling;GO:0006701//progesterone biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0031100//organ regeneration,GO:0005515//protein binding;GO:0005179//hormone activity;GO:0031700//adrenomedullin receptor binding;GO:0005102//receptor binding,-
133015,0,43,0,0,2,0,0,0,54,73,12,0,PACRGL;PARK2 co-regulated-like,-,-,-,K15053//Endocytosis
133060,0,0,0,0,0,0,0,0,16,0,0,0,OTOP1;otopetrin 1,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0042472//inner ear morphogenesis;GO:0009590//detection of gravity;GO:0031214//biomineral tissue development,-,-
133121,0,0,0,0,0,18,0,0,60,0,0,0,ENPP6;ectonucleotide pyrophosphatase/phosphodiesterase 6,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031225//anchored component of membrane,GO:0006629//lipid metabolic process;GO:0019695//choline metabolic process;GO:0016042//lipid catabolic process,GO:0008081//phosphoric diester hydrolase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0047390//glycerophosphocholine cholinephosphodiesterase activity,K08743//Ether lipid metabolism
133308,0,0,0,0,0,0,0,0,6,0,0,0,"SLC9B2;solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0034220//ion transmembrane transport;GO:1902600//hydrogen ion transmembrane transport;GO:0055085//transmembrane transport,GO:0015299//solute:proton antiporter activity,-
133383,0,0,0,0,1,0,25,0,0,0,0,0,SETD9;SET domain containing 9,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
133396,0,0,53,54,22,0,62,0,66,0,6,0,IL31RA;interleukin 31 receptor A,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,"GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0043066//negative regulation of apoptotic process;GO:0030225//macrophage differentiation;GO:0000165//MAPK cascade;GO:0030224//monocyte differentiation;GO:0042592//homeostatic process;GO:0007259//JAK-STAT cascade;GO:0043031//negative regulation of macrophage activation;GO:0008284//positive regulation of cell proliferation;GO:0006952//defense response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein",GO:0003713//transcription coactivator activity;GO:0019955//cytokine binding;GO:0004896//cytokine receptor activity;GO:0019901//protein kinase binding,K05060//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
133418,91,0,0,0,41,14,49,0,30,0,0,0,EMB;embigin,GO:0045202//synapse;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0035879//plasma membrane lactate transport,GO:0097159//organic cyclic compound binding,-
133482,119,0,0,0,0,0,1,0,21,243,0,0,"SLCO6A1;solute carrier organic anion transporter family, member 6A1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006810//transport,GO:0005215//transporter activity,-
133491,0,0,0,0,0,0,0,0,32,34,0,0,C5orf47;chromosome 5 open reading frame 47,-,-,-,-
133522,0,0,0,0,0,33,24,74,5,0,0,0,"PPARGC1B;peroxisome proliferator-activated receptor gamma, coactivator 1 beta",GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005739//mitochondrion,"GO:0051384//response to glucocorticoid;GO:0006355//regulation of transcription, DNA-templated;GO:0042327//positive regulation of phosphorylation;GO:2000273//positive regulation of receptor activity;GO:0044281//small molecule metabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0001503//ossification;GO:0044255//cellular lipid metabolic process;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0045672//positive regulation of osteoclast differentiation;GO:0006390//transcription from mitochondrial promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051591//response to cAMP;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0007015//actin filament organization;GO:0045780//positive regulation of bone resorption;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060346//bone trabecula formation",GO:0000166//nucleotide binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0030331//estrogen receptor binding;GO:0030546//receptor activator activity;GO:0050682//AF-2 domain binding;GO:0003723//RNA binding,K07202//Adipocytokine signaling pathway;Insulin signaling pathway;Huntington's disease
133558,0,0,1,0,0,20,1,0,78,121,3,0,MROH2B;maestro heat-like repeat family member 2B,-,-,-,-
133584,0,0,0,0,24,1,14,0,22,0,0,0,"EGFLAM;EGF-like, fibronectin type III and laminin G domains",GO:0005604//basement membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0005614//interstitial matrix,GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization,GO:0005539//glycosaminoglycan binding,K06254//ECM-receptor interaction;K06255//ECM-receptor interaction
133619,0,90,1,58,159,10,0,0,45,0,0,0,PRRC1;proline-rich coiled-coil 1,GO:0005794//Golgi apparatus,-,-,-
133686,27,1,0,38,152,70,24,20,46,0,0,0,"NADK2;NAD kinase 2, mitochondrial",GO:0005739//mitochondrion,GO:0006741//NADP biosynthetic process;GO:0019674//NAD metabolic process;GO:0016310//phosphorylation,GO:0042803//protein homodimerization activity;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
133688,0,0,0,0,0,30,0,55,0,0,5,0,"UGT3A1;UDP glycosyltransferase 3 family, polypeptide A1",GO:0016021//integral component of membrane;GO:0043541//UDP-N-acetylglucosamine transferase complex,GO:0008152//metabolic process,GO:0015020//glucuronosyltransferase activity,K04628//Metabolic pathways;Sphingolipid metabolism;K00699//Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis;Starch and sucrose metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions;Bile secretion;Retinol metabolism;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450
133690,0,0,0,0,0,0,0,0,13,99,0,0,CAPSL;calcyphosine-like,GO:0005737//cytoplasm,-,GO:0005509//calcium ion binding,K10840//Nucleotide excision repair;K02183//Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system;Phototransduction;Insulin signaling pathway;Tuberculosis;Pertussis;Alcoholism;Long-term potentiation;Amphetamine addiction;Oocyte meiosis;Vascular smooth muscle contraction;Phototransduction - fly;Plant-pathogen interaction;Calcium signaling pathway;Olfactory transduction;Salivary secretion;Alzheimer's disease;Neurotrophin signaling pathway;Glioma;Gastric acid secretion;Melanogenesis
1337,0,16,0,3,10,14,0,1,8,0,0,1,COX6A1;cytochrome c oxidase subunit VIa polypeptide 1,GO:0005751//mitochondrial respiratory chain complex IV;GO:0005743//mitochondrial inner membrane,GO:0006091//generation of precursor metabolites and energy;GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,GO:0004129//cytochrome-c oxidase activity,K02266//Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease;Metabolic pathways;Cardiac muscle contraction
133746,0,0,0,31,85,12,31,30,112,0,24,0,"JMY;junction mediating and regulatory protein, p53 cofactor",GO:0031252//cell leading edge;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0070060//'de novo' actin filament nucleation;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0043065//positive regulation of apoptotic process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0007050//cell cycle arrest;GO:0070358//actin polymerization-dependent cell motility;GO:0006281//DNA repair,GO:0003779//actin binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding,-
133874,0,0,49,0,0,0,0,0,11,0,0,0,C5orf58;chromosome 5 open reading frame 58,-,-,-,-
133923,0,0,25,0,0,0,11,0,0,0,0,0,ZNF474;zinc finger protein 474,-,-,GO:0046872//metal ion binding,-
133957,0,0,48,0,6,0,25,0,20,0,0,0,CCDC127;coiled-coil domain containing 127,-,-,-,-
134,0,0,0,0,0,0,0,39,11,88,5,288,ADORA1;adenosine A1 receptor,GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body;GO:0014069//postsynaptic density;GO:0032279//asymmetric synapse;GO:0030673//axolemma;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0048786//presynaptic active zone;GO:0043195//terminal bouton,"GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0055118//negative regulation of cardiac muscle contraction;GO:0050995//negative regulation of lipid catabolic process;GO:0016042//lipid catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0035307//positive regulation of protein dephosphorylation;GO:0032244//positive regulation of nucleoside transport;GO:0000186//activation of MAPKK activity;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0006612//protein targeting to membrane;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0045822//negative regulation of heart contraction;GO:0006909//phagocytosis;GO:0042323//negative regulation of circadian sleep/wake cycle, non-REM sleep;GO:0097190//apoptotic signaling pathway;GO:0043268//positive regulation of potassium ion transport;GO:0060087//relaxation of vascular smooth muscle;GO:0045908//negative regulation of vasodilation;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0050890//cognition;GO:0070256//negative regulation of mucus secretion;GO:0032900//negative regulation of neurotrophin production;GO:0007267//cell-cell signaling;GO:0001659//temperature homeostasis;GO:0045777//positive regulation of blood pressure;GO:0048167//regulation of synaptic plasticity;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0002674//negative regulation of acute inflammatory response;GO:0001973//adenosine receptor signaling pathway;GO:0002686//negative regulation of leukocyte migration;GO:0007165//signal transduction;GO:0003093//regulation of glomerular filtration;GO:0045776//negative regulation of blood pressure;GO:0006954//inflammatory response;GO:0035814//negative regulation of renal sodium excretion;GO:0002793//positive regulation of peptide secretion;GO:0007399//nervous system development;GO:0014050//negative regulation of glutamate secretion;GO:0001666//response to hypoxia;GO:0046888//negative regulation of hormone secretion;GO:0051930//regulation of sensory perception of pain",GO:0004629//phospholipase C activity;GO:0001883//purine nucleoside binding;GO:0001664//G-protein coupled receptor binding;GO:0032795//heterotrimeric G-protein binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0001609//G-protein coupled adenosine receptor activity,K04265//Morphine addiction;Neuroactive ligand-receptor interaction
1340,0,32,0,15,49,0,28,59,16,0,0,0,COX6B1;cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous),GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0044237//cellular metabolic process;GO:0021762//substantia nigra development;GO:0044281//small molecule metabolic process,GO:0004129//cytochrome-c oxidase activity,K02267//Metabolic pathways;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Cardiac muscle contraction
134083,0,0,0,0,0,2,0,0,0,0,0,0,"OR2Y1;olfactory receptor, family 2, subfamily Y, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
134111,59,0,0,0,0,8,27,0,11,3,8,0,UBE2QL1;ubiquitin-conjugating enzyme E2Q family-like 1,-,GO:0016567//protein ubiquitination,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K10582//Ubiquitin mediated proteolysis
134121,0,40,0,27,42,0,0,117,0,0,37,1,C5orf49;chromosome 5 open reading frame 49,-,-,-,-
134145,0,10,0,1,22,0,0,0,22,0,0,0,"FAM173B;family with sequence similarity 173, member B",GO:0016021//integral component of membrane,-,-,-
134147,0,37,0,38,31,0,0,0,34,0,7,0,CMBL;carboxymethylenebutenolidase homolog (Pseudomonas),GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K01061//Toluene degradation;Biosynthesis of secondary metabolites;Chlorocyclohexane and chlorobenzene degradation;Metabolic pathways;Microbial metabolism in diverse environments;Fluorobenzoate degradation;Steroid biosynthesis
134187,61,0,0,0,0,0,0,0,0,0,0,0,"POU5F2;POU domain class 5, transcription factor 2",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
134218,0,1,0,30,96,30,0,56,27,0,0,16,"DNAJC21;DnaJ (Hsp40) homolog, subfamily C, member 21",GO:0005840//ribosome,GO:0006457//protein folding,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
134265,94,0,0,0,0,24,17,0,47,0,10,0,AFAP1L1;actin filament associated protein 1-like 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0002102//podosome;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0071437//invadopodium,-,-,-
134266,0,0,0,8,1,0,0,0,14,0,0,0,"GRPEL2;GrpE-like 2, mitochondrial (E. coli)",GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0006626//protein targeting to mitochondrion;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process;GO:0050790//regulation of catalytic activity,GO:0051087//chaperone binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0051082//unfolded protein binding;GO:0042803//protein homodimerization activity,-
134285,0,0,0,0,0,0,19,0,15,1,0,0,TMEM171;transmembrane protein 171,GO:0016021//integral component of membrane,-,-,-
134288,0,0,0,0,0,18,0,44,0,0,0,0,TMEM174;transmembrane protein 174,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,-,-,-
134353,0,0,0,0,0,0,19,0,11,0,27,0,"LSM11;LSM11, U7 small nuclear RNA associated",GO:0005654//nucleoplasm;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0005683//U7 snRNP;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0006369//termination of RNA polymerase II transcription;GO:0006398//histone mRNA 3'-end processing;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process;GO:0010467//gene expression,GO:0005515//protein binding;GO:0071209//U7 snRNA binding,-
134359,102,0,0,0,0,11,0,0,0,0,8,0,POC5;POC5 centriolar protein,GO:0005813//centrosome;GO:0005814//centriole,GO:0007049//cell cycle,-,-
134429,0,38,1,17,123,26,0,136,0,0,0,0,STARD4;StAR-related lipid transfer (START) domain containing 4,-,GO:0006869//lipid transport,GO:0008289//lipid binding,-
134430,1,23,1,1,27,0,0,91,21,1,0,0,WDR36;WD repeat domain 36,GO:0032040//small-subunit processome;GO:0005730//nucleolus,GO:0006364//rRNA processing;GO:0001895//retina homeostasis;GO:0007601//visual perception;GO:0030516//regulation of axon extension;GO:0050896//response to stimulus,GO:0044822//poly(A) RNA binding,K14554//Ribosome biogenesis in eukaryotes
134466,79,0,0,0,0,17,5,0,42,0,0,0,ZNF300P1;zinc finger protein 300 pseudogene 1 (functional),GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,-
134492,0,0,0,9,28,0,0,0,0,0,0,0,NUDCD2;NudC domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0000777//condensed chromosome kinetochore;GO:0005737//cytoplasm;GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton,-,GO:0005515//protein binding,-
1345,0,0,17,24,22,0,0,0,0,1,3,263,COX6C;cytochrome c oxidase subunit VIc,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0006091//generation of precursor metabolites and energy;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,GO:0004129//cytochrome-c oxidase activity,K02268//Metabolic pathways;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Cardiac muscle contraction
134510,0,0,1,11,43,4,11,65,8,1,30,0,UBLCP1;ubiquitin-like domain containing CTD phosphatase 1,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0016311//dephosphorylation,GO:0004721//phosphoprotein phosphatase activity,-
134526,11,0,0,0,0,0,38,37,0,0,0,0,ACOT12;acyl-CoA thioesterase 12,GO:0005829//cytosol,GO:0006631//fatty acid metabolic process;GO:0006090//pyruvate metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0006084//acetyl-CoA metabolic process,GO:0008289//lipid binding;GO:0005524//ATP binding;GO:0003986//acetyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity,K01067//Pyruvate metabolism
134548,0,0,28,17,17,0,24,18,40,0,11,11,SOWAHA;sosondowah ankyrin repeat domain family member A,-,-,-,-
134549,0,2,1,19,54,38,22,0,89,0,22,0,SHROOM1;shroom family member 1,GO:0005737//cytoplasm;GO:0016460//myosin II complex;GO:0005874//microtubule,GO:0051017//actin filament bundle assembly;GO:0000902//cell morphogenesis,GO:0051015//actin filament binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
134553,0,25,0,16,43,0,0,0,0,0,0,0,C5orf24;chromosome 5 open reading frame 24,-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
1346,0,0,0,0,12,0,0,0,16,0,0,0,COX7A1;cytochrome c oxidase subunit VIIa polypeptide 1 (muscle),GO:0005746//mitochondrial respiratory chain;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:1902600//hydrogen ion transmembrane transport;GO:0006091//generation of precursor metabolites and energy,GO:0004129//cytochrome-c oxidase activity,K02270//Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Cardiac muscle contraction
134637,24,0,0,0,0,49,17,0,33,0,0,0,"ADAT2;adenosine deaminase, tRNA-specific 2",-,GO:0002100//tRNA wobble adenosine to inosine editing,GO:0008270//zinc ion binding;GO:0008251//tRNA-specific adenosine deaminase activity,-
1347,0,0,2,21,1,0,0,0,0,0,0,0,COX7A2;cytochrome c oxidase subunit VIIa polypeptide 2 (liver),GO:0005746//mitochondrial respiratory chain;GO:0070062//extracellular vesicular exosome,GO:1902600//hydrogen ion transmembrane transport,GO:0004129//cytochrome-c oxidase activity,K02270//Cardiac muscle contraction;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
134701,0,0,0,0,0,0,0,39,0,0,9,0,RIPPLY2;ripply transcriptional repressor 2,GO:0005634//nucleus,GO:0007219//Notch signaling pathway;GO:0001756//somitogenesis;GO:0036342//post-anal tail morphogenesis;GO:0007368//determination of left/right symmetry;GO:0001503//ossification;GO:0032525//somite rostral/caudal axis specification;GO:0010468//regulation of gene expression;GO:0060349//bone morphogenesis,-,-
134728,0,0,0,0,1,46,0,51,15,0,0,0,IRAK1BP1;interleukin-1 receptor-associated kinase 1 binding protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006351//transcription, DNA-templated",-,K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
134829,1,0,0,0,14,0,68,0,128,132,18,350,CLVS2;clavesin 2,GO:0005802//trans-Golgi network;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0031901//early endosome membrane,GO:0007040//lysosome organization;GO:0006810//transport,"GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005215//transporter activity",-
134860,0,0,0,0,0,0,0,0,30,0,0,0,TAAR9;trace amine associated receptor 9 (gene/pseudogene),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0001594//trace-amine receptor activity;GO:0004930//G-protein coupled receptor activity,K05051//Neuroactive ligand-receptor interaction
1349,0,0,0,1,35,0,0,0,0,0,0,0,COX7B;cytochrome c oxidase subunit VIIb,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005746//mitochondrial respiratory chain,GO:0007417//central nervous system development;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain,GO:0004129//cytochrome-c oxidase activity,K02271//Cardiac muscle contraction;Metabolic pathways;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease
134957,133,0,3,44,276,0,21,0,58,0,5,0,STXBP5;syntaxin binding protein 5 (tomosyn),GO:0005737//cytoplasm;GO:0005892//acetylcholine-gated channel complex;GO:0008021//synaptic vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0030054//cell junction,GO:0010468//regulation of gene expression;GO:0006887//exocytosis;GO:0045921//positive regulation of exocytosis;GO:0030193//regulation of blood coagulation;GO:0045920//negative regulation of exocytosis;GO:0015031//protein transport,GO:0017075//syntaxin-1 binding,-
135,5,0,17,0,0,0,0,77,0,0,7,0,ADORA2A;adenosine A2a receptor,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0007417//central nervous system development;GO:0007190//activation of adenylate cyclase activity;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006968//cellular defense response;GO:0007596//blood coagulation;GO:0006915//apoptotic process;GO:0001973//adenosine receptor signaling pathway;GO:0008015//blood circulation;GO:0006909//phagocytosis;GO:0006954//inflammatory response;GO:0007600//sensory perception,GO:0019899//enzyme binding;GO:0001609//G-protein coupled adenosine receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding,K04266//Vascular smooth muscle contraction;Calcium signaling pathway;Alcoholism;Neuroactive ligand-receptor interaction
1350,0,58,0,31,65,0,0,0,0,0,0,0,COX7C;cytochrome c oxidase subunit VIIc,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006091//generation of precursor metabolites and energy;GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,GO:0004129//cytochrome-c oxidase activity,K02272//Metabolic pathways;Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Cardiac muscle contraction
1351,0,9,0,0,22,0,0,0,13,0,10,0,COX8A;cytochrome c oxidase subunit VIIIA (ubiquitous),GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0006091//generation of precursor metabolites and energy,GO:0004129//cytochrome-c oxidase activity,K02273//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways;Cardiac muscle contraction
135112,53,0,0,11,0,7,40,16,85,0,4,0,NCOA7;nuclear receptor coactivator 7,GO:0005622//intracellular;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0035257//nuclear hormone receptor binding;GO:0005515//protein binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K12587//RNA degradation;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
135114,0,4,0,36,202,0,0,0,14,0,0,0,HINT3;histidine triad nucleotide binding protein 3,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0000166//nucleotide binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
135138,0,0,0,0,0,24,0,0,22,0,0,0,PACRG;PARK2 co-regulated,GO:0044297//cell body;GO:0005634//nucleus;GO:0097225//sperm midpiece;GO:0005739//mitochondrion,GO:0007286//spermatid development,-,-
135152,0,6,168,102,73,0,0,62,10,0,79,0,"B3GAT2;beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030204//chondroitin sulfate metabolic process,GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0046872//metal ion binding,K10157//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
135154,0,0,0,1,0,0,0,0,0,0,0,0,C6orf57;chromosome 6 open reading frame 57,GO:0005739//mitochondrion;GO:0005576//extracellular region,GO:0045087//innate immune response,-,-
1352,0,54,12,12,15,0,0,55,32,0,14,0,COX10;cytochrome c oxidase assembly homolog 10 (yeast),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,"GO:0008535//respiratory chain complex IV assembly;GO:0044281//small molecule metabolic process;GO:0048034//heme O biosynthetic process;GO:1902600//hydrogen ion transmembrane transport;GO:0000266//mitochondrial fission;GO:0006784//heme a biosynthetic process;GO:0009060//aerobic respiration;GO:0006783//heme biosynthetic process;GO:0045333//cellular respiration;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0006778//porphyrin-containing compound metabolic process",GO:0004129//cytochrome-c oxidase activity;GO:0008495//protoheme IX farnesyltransferase activity;GO:0004311//farnesyltranstransferase activity,K02257//Porphyrin and chlorophyll metabolism;Oxidative phosphorylation;Metabolic pathways;Biosynthesis of secondary metabolites
135228,81,0,0,9,0,64,24,0,40,0,11,483,CD109;CD109 molecule,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0031225//anchored component of membrane,GO:0061045//negative regulation of wound healing;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0010951//negative regulation of endopeptidase activity,GO:0050431//transforming growth factor beta binding;GO:0004867//serine-type endopeptidase inhibitor activity,-
135250,0,0,0,0,12,0,0,0,7,0,0,0,RAET1E;retinoic acid early transcript 1E,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0050776//regulation of immune response;GO:0019882//antigen processing and presentation;GO:0042267//natural killer cell mediated cytotoxicity,GO:0046703//natural killer cell lectin-like receptor binding,K07987//Natural killer cell mediated cytotoxicity
135293,0,154,1,134,380,0,0,59,14,0,0,0,PM20D2;peptidase M20 domain containing 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation
135295,0,0,0,8,1,0,0,20,17,0,0,0,SRSF12;serine/arginine-rich splicing factor 12,GO:0005654//nucleoplasm,"GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0016482//cytoplasmic transport",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0051082//unfolded protein binding;GO:0050733//RS domain binding;GO:0003723//RNA binding,K12900//Spliceosome
1353,0,212,268,511,417,26,42,0,46,130,246,0,COX11;cytochrome c oxidase assembly homolog 11 (yeast),GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0008535//respiratory chain complex IV assembly;GO:0033132//negative regulation of glucokinase activity;GO:1902600//hydrogen ion transmembrane transport;GO:0007585//respiratory gaseous exchange,GO:0004129//cytochrome-c oxidase activity;GO:0005507//copper ion binding;GO:0009055//electron carrier activity,K02258//Oxidative phosphorylation;Metabolic pathways
135398,0,0,0,0,0,12,18,0,6,0,0,0,C6orf141;chromosome 6 open reading frame 141,-,-,-,-
1355,2,83,210,263,383,0,1,169,76,25,226,0,COX15;cytochrome c oxidase assembly homolog 15 (yeast),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005746//mitochondrial respiratory chain,"GO:0007585//respiratory gaseous exchange;GO:1902600//hydrogen ion transmembrane transport;GO:0044281//small molecule metabolic process;GO:0008535//respiratory chain complex IV assembly;GO:0055114//oxidation-reduction process;GO:0006123//mitochondrial electron transport, cytochrome c to oxygen;GO:0045333//cellular respiration;GO:0006778//porphyrin-containing compound metabolic process;GO:0006783//heme biosynthetic process;GO:0006784//heme a biosynthetic process","GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors;GO:0004129//cytochrome-c oxidase activity",K02259//Two-component system;Porphyrin and chlorophyll metabolism;Oxidative phosphorylation;Metabolic pathways;Biosynthesis of secondary metabolites
1356,78,108,169,207,155,10,51,46,79,38,112,0,CP;ceruloplasmin (ferroxidase),GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005765//lysosomal membrane,GO:0055114//oxidation-reduction process;GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport;GO:0006825//copper ion transport,GO:0004322//ferroxidase activity;GO:0005507//copper ion binding;GO:0051087//chaperone binding,K13624//Porphyrin and chlorophyll metabolism
135656,0,0,0,0,0,0,0,0,1,0,0,0,DPCR1;diffuse panbronchiolitis critical region 1,GO:0016021//integral component of membrane,-,-,K10955//Amoebiasis;Vibrio cholerae infection
1357,11,0,19,0,0,22,17,0,0,0,10,0,CPA1;carboxypeptidase A1 (pancreatic),GO:0005615//extracellular space,GO:0006508//proteolysis,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,K08779//Pancreatic secretion;Protein digestion and absorption
1358,0,0,0,0,0,0,72,1,29,0,0,0,CPA2;carboxypeptidase A2 (pancreatic),GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0007039//protein catabolic process in the vacuole,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0004180//carboxypeptidase activity,K01298//Pancreatic secretion;Protein digestion and absorption
135886,3,0,0,0,1,0,0,0,5,0,0,0,WBSCR28;Williams-Beuren syndrome chromosome region 28,GO:0016021//integral component of membrane,-,-,-
135892,9,0,0,0,0,0,0,33,23,0,5,0,TRIM50;tripartite motif containing 50,GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
1359,0,0,0,0,0,0,20,0,46,0,0,0,CPA3;carboxypeptidase A3 (mast cell),GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0030133//transport vesicle,GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0002003//angiotensin maturation,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,K08780//Protein digestion and absorption;Pancreatic secretion;Renin-angiotensin system
135924,27,0,0,0,0,9,0,0,0,0,0,0,"OR9A2;olfactory receptor, family 9, subfamily A, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
135927,0,0,0,0,0,0,0,0,1,0,0,0,C7orf34;chromosome 7 open reading frame 34,GO:0005576//extracellular region,-,-,-
135932,0,23,32,11,34,0,21,0,9,0,38,0,TMEM139;transmembrane protein 139,GO:0016021//integral component of membrane,-,-,-
135935,0,0,0,0,0,0,0,0,22,0,14,0,NOBOX;NOBOX oogenesis homeobox,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0001541//ovarian follicle development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0048477//oogenesis",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
135941,0,0,0,0,0,0,0,0,9,0,0,0,"OR2A14;olfactory receptor, family 2, subfamily A, member 14",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
135946,0,0,0,0,0,0,0,0,23,0,0,0,"OR6B1;olfactory receptor, family 6, subfamily B, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
135948,0,0,0,0,0,0,0,0,13,0,0,0,"OR2F2;olfactory receptor, family 2, subfamily F, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
136,0,19,0,32,4,0,0,0,9,0,24,0,ADORA2B;adenosine A2b receptor,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007254//JNK cascade;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0032722//positive regulation of chemokine production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007588//excretion;GO:0007190//activation of adenylate cyclase activity;GO:0000187//activation of MAPK activity;GO:0043306//positive regulation of mast cell degranulation;GO:0001973//adenosine receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0002882//positive regulation of chronic inflammatory response to non-antigenic stimulus;GO:0031668//cellular response to extracellular stimulus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006968//cellular defense response;GO:0060087//relaxation of vascular smooth muscle;GO:0031284//positive regulation of guanylate cyclase activity;GO:0010575//positive regulation vascular endothelial growth factor production,GO:0001609//G-protein coupled adenosine receptor activity,K04267//Vascular smooth muscle contraction;Calcium signaling pathway;Alcoholism;Neuroactive ligand-receptor interaction
1360,0,0,0,0,0,0,0,0,1,0,0,0,CPB1;carboxypeptidase B1 (tissue),GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0004180//carboxypeptidase activity,K01291//Pancreatic secretion;Protein digestion and absorption
136051,0,0,51,0,0,0,0,0,0,0,16,0,ZNF786;zinc finger protein 786,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
1361,75,0,0,0,0,0,3,118,24,0,0,0,CPB2;carboxypeptidase B2 (plasma),GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:2000346//negative regulation of hepatocyte proliferation;GO:0006508//proteolysis;GO:0071333//cellular response to glucose stimulus;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0042730//fibrinolysis;GO:0009408//response to heat;GO:0007596//blood coagulation;GO:0051918//negative regulation of fibrinolysis;GO:0010757//negative regulation of plasminogen activation;GO:0042493//response to drug;GO:0097421//liver regeneration,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,K01300//Complement and coagulation cascades;Protein digestion and absorption;Pancreatic secretion
1362,76,31,1,18,1,8,20,45,20,0,1,0,CPD;carboxypeptidase D,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding;GO:0004185//serine-type carboxypeptidase activity,-
136227,87,33,22,3,10,16,0,77,33,91,69,927,"COL26A1;collagen, type XXVI, alpha 1",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0005581//collagen trimer,GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0010811//positive regulation of cell-substrate adhesion,-,-
136242,0,0,11,0,0,0,0,0,23,0,10,0,"PRSS37;protease, serine, 37",GO:0005634//nucleus;GO:0005576//extracellular region,GO:0016477//cell migration;GO:0007339//binding of sperm to zona pellucida;GO:0051604//protein maturation;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01312//Neuroactive ligand-receptor interaction;Influenza A;Protein digestion and absorption;Pancreatic secretion
136263,0,0,0,0,0,0,0,40,0,0,0,0,SSMEM1;serine-rich single-pass membrane protein 1,GO:0016021//integral component of membrane,-,-,-
136288,0,0,0,0,4,0,17,0,21,0,0,0,C7orf57;chromosome 7 open reading frame 57,-,-,-,-
1363,0,0,0,14,63,11,0,0,53,1,0,0,CPE;carboxypeptidase E,GO:0005634//nucleus;GO:0030658//transport vesicle membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0030667//secretory granule membrane,GO:0007218//neuropeptide signaling pathway;GO:0072657//protein localization to membrane;GO:0003214//cardiac left ventricle morphogenesis;GO:0006508//proteolysis;GO:0008152//metabolic process;GO:0044267//cellular protein metabolic process;GO:0030070//insulin processing;GO:0006464//cellular protein modification process,GO:0004180//carboxypeptidase activity;GO:0042043//neurexin family protein binding;GO:0004181//metallocarboxypeptidase activity;GO:0050839//cell adhesion molecule binding;GO:0008270//zinc ion binding,K01294//Type I diabetes mellitus
136306,0,0,18,0,0,28,0,0,42,0,0,0,SVOPL;SVOP-like,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,K06258//ECM-receptor interaction;K08204//Bile secretion
136332,0,0,0,0,0,58,2,0,74,0,0,0,LRGUK;leucine-rich repeats and guanylate kinase domain containing,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0016310//phosphorylation,GO:0005524//ATP binding;GO:0016301//kinase activity,K00942//Metabolic pathways;Purine metabolism
136371,0,0,0,0,0,0,0,0,15,0,1,0,ASB10;ankyrin repeat and SOCS box containing 10,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
1364,0,0,0,0,0,0,0,0,1,0,0,0,CLDN4;claudin 4,GO:0016328//lateral plasma membrane;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0061436//establishment of skin barrier;GO:0007165//signal transduction;GO:0032570//response to progesterone;GO:0007565//female pregnancy,GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity,K06087//Hepatitis C;Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection
1365,0,0,0,0,0,1,0,0,36,0,0,0,CLDN3;claudin 3,GO:0016328//lateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005923//tight junction,GO:0001666//response to hypoxia;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0007165//signal transduction,GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0004888//transmembrane signaling receptor activity,K06087//Cell adhesion molecules (CAMs);Tight junction;Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
136541,0,0,0,0,0,14,0,0,0,0,0,0,"PRSS58;protease, serine, 58",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01312//Pancreatic secretion;Influenza A;Neuroactive ligand-receptor interaction;Protein digestion and absorption
1366,0,0,0,0,1,4,0,0,9,0,0,0,CLDN7;claudin 7,GO:0016328//lateral plasma membrane;GO:0005923//tight junction;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules,GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Tight junction;Cell adhesion molecules (CAMs);Hepatitis C
136647,0,0,0,0,1,0,40,0,0,0,0,0,MPLKIP;M-phase specific PLK1 interacting protein,GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody,GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
1368,0,22,0,11,35,20,16,0,47,0,0,0,CPM;carboxypeptidase M,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,GO:0009653//anatomical structure morphogenesis;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004180//carboxypeptidase activity;GO:0004181//metallocarboxypeptidase activity,-
136853,51,27,0,0,0,34,0,132,16,0,26,0,"SRCRB4D;scavenger receptor cysteine rich domain containing, group B (4 domains)",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0006898//receptor-mediated endocytosis,GO:0005044//scavenger receptor activity,K13912//Salivary secretion
136895,0,0,0,0,7,0,15,0,2,72,0,0,C7orf31;chromosome 7 open reading frame 31,-,-,-,-
1369,0,0,0,0,0,14,0,61,23,0,0,0,"CPN1;carboxypeptidase N, polypeptide 1",GO:0005615//extracellular space,GO:0051384//response to glucocorticoid;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,-
1370,0,0,0,0,0,0,38,0,64,0,13,0,"CPN2;carboxypeptidase N, polypeptide 2",GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0050821//protein stabilization;GO:0050790//regulation of catalytic activity,GO:0030234//enzyme regulator activity,-
137075,8,0,0,0,0,0,0,0,12,0,9,0,CLDN23;claudin 23,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0070830//tight junction assembly;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045216//cell-cell junction organization;GO:0034329//cell junction assembly,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Tight junction;Cell adhesion molecules (CAMs);Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
1371,0,0,0,0,10,0,0,0,0,251,0,0,CPOX;coproporphyrinogen oxidase,GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0010288//response to lead ion;GO:0046685//response to arsenic-containing substance;GO:0055114//oxidation-reduction process;GO:0006778//porphyrin-containing compound metabolic process;GO:0006783//heme biosynthetic process;GO:0010039//response to iron ion;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0051597//response to methylmercury;GO:0044281//small molecule metabolic process;GO:0017085//response to insecticide,GO:0042803//protein homodimerization activity;GO:0005212//structural constituent of eye lens;GO:0004109//coproporphyrinogen oxidase activity,K00228//Porphyrin and chlorophyll metabolism;Salmonella infection;Metabolic pathways;Biosynthesis of secondary metabolites
137209,0,0,0,3,9,22,0,0,78,0,0,0,ZNF572;zinc finger protein 572,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1373,1,0,0,5,0,24,26,0,85,0,6,110,"CPS1;carbamoyl-phosphate synthase 1, mitochondrial",GO:0005759//mitochondrial matrix;GO:0043234//protein complex;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0042645//mitochondrial nucleoid,GO:0042493//response to drug;GO:0071548//response to dexamethasone;GO:0014075//response to amine;GO:0071377//cellular response to glucagon stimulus;GO:0071400//cellular response to oleic acid;GO:0000050//urea cycle;GO:0007494//midgut development;GO:0070409//carbamoyl phosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0009636//response to toxic substance;GO:0070365//hepatocyte differentiation;GO:0042594//response to starvation;GO:0050667//homocysteine metabolic process;GO:0032496//response to lipopolysaccharide;GO:0060416//response to growth hormone;GO:0032094//response to food;GO:0046209//nitric oxide metabolic process;GO:0019433//triglyceride catabolic process;GO:0010043//response to zinc ion;GO:0045909//positive regulation of vasodilation;GO:0006543//glutamine catabolic process;GO:0019240//citrulline biosynthetic process;GO:0071320//cellular response to cAMP;GO:0043200//response to amino acid;GO:0034641//cellular nitrogen compound metabolic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006508//proteolysis;GO:0055081//anion homeostasis;GO:0005980//glycogen catabolic process,GO:0004175//endopeptidase activity;GO:0072341//modified amino acid binding;GO:0005543//phospholipid binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0004087//carbamoyl-phosphate synthase (ammonia) activity;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0016595//glutamate binding,"K01948//Arginine and proline metabolism;Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism"
137362,0,0,0,0,0,1,0,50,10,116,0,0,GOT1L1;glutamic-oxaloacetic transaminase 1-like 1,GO:0005737//cytoplasm,GO:0006520//cellular amino acid metabolic process;GO:0009058//biosynthetic process,GO:0030170//pyridoxal phosphate binding;GO:0008483//transaminase activity,"K14454//Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Cysteine and methionine metabolism;Isoquinoline alkaloid biosynthesis;Phenylalanine, tyrosine and tryptophan biosynthesis;Arginine and proline metabolism;Phenylalanine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;Tyrosine metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
137392,0,0,0,20,9,33,0,42,66,0,0,0,"FAM92A1;family with sequence similarity 92, member A1",-,-,-,K02258//Metabolic pathways;Oxidative phosphorylation
1374,6,0,0,11,37,0,44,0,23,0,3,491,CPT1A;carnitine palmitoyltransferase 1A (liver),GO:0031307//integral component of mitochondrial outer membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane,GO:0030855//epithelial cell differentiation;GO:0071398//cellular response to fatty acid;GO:0006641//triglyceride metabolic process;GO:0042755//eating behavior;GO:0006006//glucose metabolic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0009437//carnitine metabolic process;GO:0014070//response to organic cyclic compound;GO:0006853//carnitine shuttle;GO:0050796//regulation of insulin secretion;GO:0006635//fatty acid beta-oxidation;GO:0001676//long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0042493//response to drug;GO:0051260//protein homooligomerization;GO:0044255//cellular lipid metabolic process,GO:0004095//carnitine O-palmitoyltransferase activity;GO:0042802//identical protein binding,K08765//Fatty acid metabolism;PPAR signaling pathway;Adipocytokine signaling pathway
137492,0,16,1,33,24,15,0,0,0,0,0,0,VPS37A;vacuolar protein sorting 37 homolog A (S. cerevisiae),GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0010008//endosome membrane;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0019082//viral protein processing;GO:0075733//intracellular transport of virus;GO:0061024//membrane organization;GO:0016197//endosomal transport;GO:0019068//virion assembly;GO:0015031//protein transport;GO:0008219//cell death;GO:0016032//viral process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0019058//viral life cycle,-,K12185//Endocytosis
1375,0,0,0,0,0,6,0,62,5,0,0,0,CPT1B;carnitine palmitoyltransferase 1B (muscle),GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006853//carnitine shuttle;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0006635//fatty acid beta-oxidation,GO:0004095//carnitine O-palmitoyltransferase activity,K08765//Adipocytokine signaling pathway;PPAR signaling pathway;Fatty acid metabolism
1376,0,0,52,22,32,0,0,0,73,0,22,0,CPT2;carnitine palmitoyltransferase 2,GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006853//carnitine shuttle;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0006635//fatty acid beta-oxidation,GO:0004095//carnitine O-palmitoyltransferase activity,K08766//PPAR signaling pathway;Fatty acid metabolism
137682,0,0,0,0,0,0,0,0,18,0,0,0,"NDUFAF6;NADH dehydrogenase (ubiquinone) complex I, assembly factor 6",GO:0005743//mitochondrial inner membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0009058//biosynthetic process;GO:0032981//mitochondrial respiratory chain complex I assembly,GO:0016740//transferase activity,-
137695,95,0,0,7,0,0,9,0,3,0,0,0,TMEM68;transmembrane protein 68,GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K11447//Transcriptional misregulation in cancer
137735,0,0,0,0,0,0,23,0,18,0,0,0,ABRA;actin-binding Rho activating protein,GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0030017//sarcomere,"GO:0035025//positive regulation of Rho protein signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000060//protein import into nucleus, translocation;GO:0006351//transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity",GO:0003713//transcription coactivator activity;GO:0003779//actin binding,-
137797,0,0,0,0,0,0,0,0,12,7,0,0,LYPD2;LY6/PLAUR domain containing 2,GO:0031225//anchored component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,-,-
1378,4,0,0,0,0,9,19,0,56,0,0,0,CR1;complement component (3b/4b) receptor 1 (Knops blood group),GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,"GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0002430//complement receptor mediated signaling pathway;GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0045087//innate immune response",GO:0001855//complement component C4b binding,K04011//Hematopoietic cell lineage;Leishmaniasis;Malaria;Complement and coagulation cascades;Tuberculosis;Legionellosis
137814,0,0,0,0,0,0,0,0,12,0,25,0,NKX2-6;NK2 homeobox 6,GO:0005634//nucleus,"GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-templated;GO:0055014//atrial cardiac muscle cell development;GO:0021854//hypothalamus development;GO:0043586//tongue development;GO:0055015//ventricular cardiac muscle cell development;GO:0048565//digestive tract development;GO:0006355//regulation of transcription, DNA-templated;GO:0035050//embryonic heart tube development;GO:0060039//pericardium development;GO:0060037//pharyngeal system development;GO:0008284//positive regulation of cell proliferation;GO:0030154//cell differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
137835,135,0,0,0,0,18,0,0,9,0,0,0,TMEM71;transmembrane protein 71,GO:0016021//integral component of membrane,-,-,-
137868,0,0,0,0,0,14,0,0,14,0,0,0,"SGCZ;sarcoglycan, zeta",GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0016012//sarcoglycan complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0046716//muscle cell cellular homeostasis;GO:0055001//muscle cell development;GO:0061024//membrane organization,-,K12563//Viral myocarditis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
137872,0,28,0,2,16,0,0,0,40,0,0,0,"ADHFE1;alcohol dehydrogenase, iron containing, 1",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006103//2-oxoglutarate metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0015993//molecular hydrogen transport;GO:0044237//cellular metabolic process,GO:0047988//hydroxyacid-oxoacid transhydrogenase activity;GO:0046872//metal ion binding,-
137886,0,0,0,10,31,0,0,0,38,0,9,0,UBXN2B;UBX domain protein 2B,GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,-,-,K14012//Protein processing in endoplasmic reticulum
1379,0,0,0,0,0,15,0,0,9,270,0,0,CR1L;complement component (3b/4b) receptor 1-like,GO:0005737//cytoplasm;GO:0043235//receptor complex;GO:0005576//extracellular region;GO:0016020//membrane,-,-,K04011//Legionellosis;Tuberculosis;Complement and coagulation cascades;Malaria;Leishmaniasis;Hematopoietic cell lineage
137902,8,0,0,0,0,5,28,0,77,0,0,0,PXDNL;peroxidasin homolog (Drosophila)-like,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0055114//oxidation-reduction process;GO:0042744//hydrogen peroxide catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004601//peroxidase activity;GO:0020037//heme binding;GO:0004519//endonuclease activity;GO:0046872//metal ion binding,K00431//Hematopoietic cell lineage;Tyrosine metabolism;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;Autoimmune thyroid disease;Metabolic pathways
137964,0,53,13,2,16,36,28,0,89,0,22,0,AGPAT6;1-acylglycerol-3-phosphate O-acyltransferase 6,GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0046339//diacylglycerol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0007595//lactation;GO:0008610//lipid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0040014//regulation of multicellular organism growth;GO:0019432//triglyceride biosynthetic process;GO:0006637//acyl-CoA metabolic process;GO:0044281//small molecule metabolic process;GO:0006631//fatty acid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0002071//glandular epithelial cell maturation;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004366//glycerol-3-phosphate O-acyltransferase activity,K13506//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism
137970,94,0,0,6,0,0,35,0,43,0,0,246,UNC5D;unc-5 homolog D (C. elegans),GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0006915//apoptotic process;GO:2001222//regulation of neuron migration;GO:0021859//pyramidal neuron differentiation;GO:0007165//signal transduction;GO:0007411//axon guidance,-,K07521//Axon guidance
137994,0,0,0,15,0,11,6,1,26,0,0,0,LETM2;leucine zipper-EF-hand containing transmembrane protein 2,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation
1380,0,0,19,0,0,32,0,0,48,0,1,0,CR2;complement component (3d/Epstein Barr virus) receptor 2,GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0045087//innate immune response;GO:0030183//B cell differentiation;GO:0042100//B cell proliferation;GO:0006955//immune response;GO:0002430//complement receptor mediated signaling pathway;GO:0006958//complement activation, classical pathway",GO:0042803//protein homodimerization activity;GO:0004888//transmembrane signaling receptor activity;GO:0003677//DNA binding;GO:0004875//complement receptor activity;GO:0001848//complement binding,K04012//Complement and coagulation cascades;Epstein-Barr virus infection;B cell receptor signaling pathway;Hematopoietic cell lineage
138009,0,0,0,0,0,18,0,12,0,0,0,0,DCAF4L2;DDB1 and CUL4 associated factor 4-like 2,-,-,-,-
138046,1,0,0,0,0,0,0,0,16,75,1,0,RALYL;RALY RNA binding protein-like,-,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
138050,91,0,0,0,11,14,25,0,41,0,0,0,HGSNAT;heparan-alpha-glucosaminide N-acetyltransferase,GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007041//lysosomal transport;GO:0051259//protein oligomerization;GO:0005975//carbohydrate metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K10532//Glycosaminoglycan degradation;Metabolic pathways;Lysosome
138065,0,0,0,0,0,0,0,0,8,0,5,0,RNF183;ring finger protein 183,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
1381,0,0,1,0,0,0,0,0,0,0,0,0,CRABP1;cellular retinoic acid binding protein 1,GO:0005829//cytosol,GO:0007275//multicellular organismal development;GO:0007165//signal transduction;GO:0006810//transport,GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0005515//protein binding;GO:0005501//retinoid binding;GO:0005215//transporter activity;GO:0001972//retinoic acid binding,K08756//PPAR signaling pathway;K08754//PPAR signaling pathway;K08752//PPAR signaling pathway
138151,0,1,0,0,19,0,0,29,16,0,6,0,"NACC2;NACC family member 2, BEN and BTB (POZ) domain containing",GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0016581//NuRD complex;GO:0016604//nuclear body,"GO:0034629//cellular protein complex localization;GO:0008284//positive regulation of cell proliferation;GO:0051260//protein homooligomerization;GO:1900477//negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010608//posttranscriptional regulation of gene expression;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008285//negative regulation of cell proliferation",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0004407//histone deacetylase activity,-
138162,0,0,0,0,1,14,2,0,0,0,0,0,C9orf116;chromosome 9 open reading frame 116,-,-,-,-
138199,0,54,0,9,51,0,28,0,0,0,0,8,C9orf41;chromosome 9 open reading frame 41,-,-,-,-
1382,0,0,0,0,7,0,0,0,2,0,0,0,CRABP2;cellular retinoic acid binding protein 2,GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008544//epidermis development;GO:0006810//transport;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated",GO:0005215//transporter activity;GO:0005501//retinoid binding;GO:0016918//retinal binding;GO:0019841//retinol binding,K08754//PPAR signaling pathway;K08752//PPAR signaling pathway;K08756//PPAR signaling pathway
138240,0,0,24,0,0,0,0,0,14,0,0,0,C9orf57;chromosome 9 open reading frame 57,GO:0016021//integral component of membrane,-,-,-
138241,0,0,0,0,10,0,0,0,21,0,14,0,C9orf85;chromosome 9 open reading frame 85,-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
138307,0,0,0,0,9,0,0,66,12,0,0,0,LCN8;lipocalin 8,GO:0005576//extracellular region,GO:0009725//response to hormone;GO:0006810//transport,-,-
138311,0,58,0,51,83,0,1,0,1,0,135,0,"FAM69B;family with sequence similarity 69, member B",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
1384,97,4,2,8,45,6,20,0,49,0,15,230,CRAT;carnitine O-acetyltransferase,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,"GO:0006810//transport;GO:0019254//carnitine metabolic process, CoA-linked;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process",GO:0004092//carnitine O-acetyltransferase activity;GO:0005102//receptor binding,K00624//Peroxisome
138428,0,0,0,15,0,0,0,48,20,0,15,0,PTRH1;peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae),GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0044822//poly(A) RNA binding;GO:0004045//aminoacyl-tRNA hydrolase activity,-
138429,57,0,0,0,0,12,0,0,1,0,0,0,PIP5KL1;phosphatidylinositol-4-phosphate 5-kinase-like 1,GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0016020//membrane,GO:0046854//phosphatidylinositol phosphorylation,GO:0005524//ATP binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity,K13712//Inositol phosphate metabolism;Metabolic pathways;Endocytosis
138474,0,0,0,0,1,7,27,0,0,0,0,0,"TAF1L;TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like",GO:0005669//transcription factor TFIID complex,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007140//male meiosis;GO:0006468//protein phosphorylation;GO:0016573//histone acetylation;GO:0006352//DNA-templated transcription, initiation;GO:0045893//positive regulation of transcription, DNA-templated",GO:0070577//lysine-acetylated histone binding;GO:0017025//TBP-class protein binding;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0004674//protein serine/threonine kinase activity,K03125//Basal transcription factors
1385,0,58,0,9,102,26,42,0,26,0,20,0,CREB1;cAMP responsive element binding protein 1,GO:0005719//nuclear euchromatin;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0008361//regulation of cell size;GO:0060430//lung saccule development;GO:0045087//innate immune response;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0033762//response to glucagon;GO:0048015//phosphatidylinositol-mediated signaling;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007595//lactation;GO:0040018//positive regulation of multicellular organism growth;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0007613//memory;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0007623//circadian rhythm;GO:0042493//response to drug;GO:0060509//Type I pneumocyte differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0010033//response to organic substance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034134//toll-like receptor 2 signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021983//pituitary gland development;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0046887//positive regulation of hormone secretion;GO:0045672//positive regulation of osteoclast differentiation;GO:0007202//activation of phospholipase C activity;GO:0033363//secretory granule organization;GO:0007411//axon guidance;GO:0051403//stress-activated MAPK cascade;GO:0050821//protein stabilization;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0071294//cellular response to zinc ion;GO:0007165//signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0046889//positive regulation of lipid biosynthetic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007268//synaptic transmission;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0006468//protein phosphorylation",GO:0035497//cAMP response element binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003712//transcription cofactor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019899//enzyme binding,K05870//Huntington's disease;HTLV-I infection;Cholinergic synapse;Dopaminergic synapse;Cocaine addiction;Tuberculosis;Prostate cancer;Alcoholism;Vasopressin-regulated water reabsorption;Amphetamine addiction;Osteoclast differentiation;Melanogenesis;Antigen processing and presentation
1386,0,4,0,13,62,0,0,0,9,0,0,0,ATF2;activating transcription factor 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035861//site of double-strand break;GO:0005730//nucleolus;GO:0005741//mitochondrial outer membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0031573//intra-S DNA damage checkpoint;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:1902110//positive regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0060612//adipose tissue development;GO:0006325//chromatin organization;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0006974//cellular response to DNA damage stimulus;GO:0045444//fat cell differentiation;GO:0016573//histone acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003151//outflow tract morphogenesis;GO:0006970//response to osmotic stress;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway",GO:0008140//cAMP response element binding protein binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004402//histone acetyltransferase activity;GO:0019901//protein kinase binding;GO:0003682//chromatin binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0035497//cAMP response element binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0001102//RNA polymerase II activating transcription factor binding,K04450//Influenza A;Alcoholism;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction
138639,57,21,0,1,0,10,0,0,12,0,0,0,PTPDC1;protein tyrosine phosphatase domain containing 1,-,GO:0007224//smoothened signaling pathway;GO:0060271//cilium morphogenesis;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,K06639//Cell cycle - yeast;Cell cycle;Meiosis - yeast
138649,0,0,0,2,0,48,0,0,88,0,37,0,"ANKRD19P;ankyrin repeat domain 19, pseudogene",-,-,-,K15410//Herpes simplex infection
1387,0,35,0,46,49,45,62,38,34,40,1,0,CREBBP;CREB binding protein,GO:0005667//transcription factor complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0000940//condensed chromosome outer kinetochore;GO:0005730//nucleolus;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0000123//histone acetyltransferase complex,"GO:0008589//regulation of smoothened signaling pathway;GO:0010467//gene expression;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042733//embryonic digit morphogenesis;GO:0044281//small molecule metabolic process;GO:0071456//cellular response to hypoxia;GO:0042592//homeostatic process;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0001666//response to hypoxia;GO:0030718//germ-line stem cell maintenance;GO:0007165//signal transduction;GO:0007219//Notch signaling pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016573//histone acetylation;GO:0048511//rhythmic process;GO:0016032//viral process",GO:0004871//signal transducer activity;GO:0004402//histone acetyltransferase activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0043426//MRF binding;GO:0002039//p53 binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0016407//acetyltransferase activity;GO:0003713//transcription coactivator activity;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K04498//Huntington's disease;Pathways in cancer;Influenza A;Long-term potentiation;Prostate cancer;Tuberculosis;Wnt signaling pathway;Herpes simplex infection;Epstein-Barr virus infection;Renal cell carcinoma;Cell cycle;Adherens junction;Jak-STAT signaling pathway;HTLV-I infection;TGF-beta signaling pathway;Melanogenesis;Notch signaling pathway
138715,0,0,0,0,0,10,0,0,17,0,0,0,ARID3C;AT rich interactive domain 3C (BRIGHT-like),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045121//membrane raft,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
138716,0,1,0,0,0,0,35,0,1,0,0,0,RPP25L;ribonuclease P/MRP 25kDa subunit-like,GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,K14525//Ribosome biogenesis in eukaryotes;RNA transport
138724,115,0,0,7,1,23,0,1,0,155,0,0,C9orf131;chromosome 9 open reading frame 131,-,-,-,-
138799,0,0,0,0,0,0,0,0,0,6,0,0,"OR13C5;olfactory receptor, family 13, subfamily C, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1388,2,0,0,0,0,0,0,0,0,0,0,0,ATF6B;activating transcription factor 6 beta,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005622//intracellular,"GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006986//response to unfolded protein",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,K09049//Dopaminergic synapse;Cocaine addiction;Amphetamine addiction;Protein processing in endoplasmic reticulum;Alcoholism
138803,0,0,0,0,0,0,0,0,1,0,0,0,"OR13C3;olfactory receptor, family 13, subfamily C, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
138804,0,0,0,0,0,0,0,0,9,0,0,0,"OR13C4;olfactory receptor, family 13, subfamily C, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
138881,0,0,0,0,0,0,9,0,57,0,21,0,"OR1L8;olfactory receptor, family 1, subfamily L, member 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
138883,0,0,0,0,0,0,0,2,0,0,0,0,"OR1N1;olfactory receptor, family 1, subfamily N, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
1389,0,27,1,88,293,0,0,57,37,0,18,310,CREBL2;cAMP responsive element binding protein-like 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0046889//positive regulation of lipid biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0050821//protein stabilization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0045600//positive regulation of fat cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
1390,31,0,0,0,0,23,0,52,0,54,0,0,CREM;cAMP responsive element modulator,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006687//glycosphingolipid metabolic process",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008140//cAMP response element binding protein binding,K09052//HTLV-I infection
139065,26,0,0,0,13,50,19,0,63,0,0,0,"SLITRK4;SLIT and NTRK-like family, member 4",GO:0016021//integral component of membrane,-,-,K06838//Axon guidance;K06850//Axon guidance
139081,0,0,19,0,0,0,0,0,8,0,0,0,"MAGEC3;melanoma antigen family C, 3",-,-,-,K12464//Neurotrophin signaling pathway
139105,0,0,0,0,0,8,0,0,13,0,0,0,BEND2;BEN domain containing 2,-,-,-,K11447//Transcriptional misregulation in cancer;K04006//Complement and coagulation cascades;Viral myocarditis;Hematopoietic cell lineage;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
139135,30,0,0,0,0,0,20,0,8,0,0,0,PASD1;PAS domain containing 1,GO:0005634//nucleus,GO:0007165//signal transduction,GO:0004871//signal transducer activity,K09026//Circadian rhythm - mammal;K02223//Dopaminergic synapse;Herpes simplex infection;Circadian rhythm - fly;Circadian rhythm - mammal
139170,0,0,0,0,0,11,1,0,28,0,0,0,DCAF12L1;DDB1 and CUL4 associated factor 12-like 1,-,-,-,-
139189,1,0,0,0,0,32,0,53,80,0,27,0,"DGKK;diacylglycerol kinase, kappa",GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0006979//response to oxidative stress;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0007596//blood coagulation;GO:0046339//diacylglycerol metabolic process,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity,K00901//Metabolic pathways;Glycerolipid metabolism;Phosphatidylinositol signaling system;Glycerophospholipid metabolism
1392,99,0,0,0,0,0,4,0,0,0,0,0,CRH;corticotropin releasing hormone,GO:0043196//varicosity;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0043204//perikaryon,"GO:0030819//positive regulation of cAMP biosynthetic process;GO:0030325//adrenal gland development;GO:0045471//response to ethanol;GO:0050801//ion homeostasis;GO:0071314//cellular response to cocaine;GO:0007611//learning or memory;GO:0001963//synaptic transmission, dopaminergic;GO:0035902//response to immobilization stress;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0042493//response to drug;GO:0032811//negative regulation of epinephrine secretion;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0010700//negative regulation of norepinephrine secretion;GO:0007268//synaptic transmission;GO:0048265//response to pain;GO:0043627//response to estrogen;GO:0030324//lung development;GO:0090280//positive regulation of calcium ion import;GO:0016101//diterpenoid metabolic process;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0007567//parturition;GO:0045776//negative regulation of blood pressure;GO:0007165//signal transduction;GO:0007616//long-term memory;GO:0051461//positive regulation of corticotropin secretion;GO:0006954//inflammatory response;GO:0045472//response to ether;GO:0008306//associative learning;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0010628//positive regulation of gene expression;GO:0010942//positive regulation of cell death;GO:0021854//hypothalamus development;GO:2000854//positive regulation of corticosterone secretion;GO:0035641//locomotory exploration behavior;GO:0006704//glucocorticoid biosynthetic process;GO:0014062//regulation of serotonin secretion;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell proliferation;GO:0070093//negative regulation of glucagon secretion;GO:0010629//negative regulation of gene expression;GO:0001934//positive regulation of protein phosphorylation;GO:0060548//negative regulation of cell death;GO:2000987//positive regulation of behavioral fear response;GO:0033685//negative regulation of luteinizing hormone secretion;GO:0060291//long-term synaptic potentiation;GO:0071549//cellular response to dexamethasone stimulus;GO:0051412//response to corticosterone;GO:0007631//feeding behavior;GO:0042322//negative regulation of circadian sleep/wake cycle, REM sleep;GO:0051464//positive regulation of cortisol secretion",GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0005102//receptor binding;GO:0051430//corticotropin-releasing hormone receptor 1 binding,K05256//Alcoholism;Long-term depression
139201,0,0,0,0,0,0,43,85,0,0,0,0,MAP2K4P1;mitogen-activated protein kinase kinase 4 pseudogene 1,-,-,-,K04430//Toll-like receptor signaling pathway;Influenza A;Fc epsilon RI signaling pathway;HTLV-I infection;Chagas disease (American trypanosomiasis);GnRH signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;ErbB signaling pathway;MAPK signaling pathway
139212,0,0,0,0,0,0,0,0,3,0,0,0,PIH1D3;PIH1 domain containing 3,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K09254//Transcriptional misregulation in cancer
139221,0,17,0,0,0,0,0,51,43,0,17,0,MUM1L1;melanoma associated antigen (mutated) 1-like 1,GO:0070062//extracellular vesicular exosome,-,-,-
139231,0,2,0,54,168,5,0,69,57,0,0,0,"FAM199X;family with sequence similarity 199, X-linked",-,-,-,-
139285,180,0,0,0,0,37,26,0,60,0,0,1,AMER1;APC membrane recruitment protein 1,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005634//nucleus,GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060348//bone development;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0060612//adipose tissue development,"GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",-
1393,0,0,0,0,0,0,0,0,31,82,0,0,CRHBP;corticotropin releasing hormone binding protein,GO:0005874//microtubule;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0005771//multivesicular body;GO:0005767//secondary lysosome;GO:0005622//intracellular;GO:0043204//perikaryon;GO:0043196//varicosity;GO:0043679//axon terminus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0031045//dense core granule;GO:0030425//dendrite,"GO:0007611//learning or memory;GO:0071391//cellular response to estrogen stimulus;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:0071314//cellular response to cocaine;GO:0071277//cellular response to calcium ion;GO:0007565//female pregnancy;GO:0001963//synaptic transmission, dopaminergic;GO:0045055//regulated secretory pathway;GO:0071392//cellular response to estradiol stimulus;GO:1900011//negative regulation of corticotropin-releasing hormone receptor activity;GO:0035690//cellular response to drug;GO:0048149//behavioral response to ethanol;GO:0035865//cellular response to potassium ion;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0007165//signal transduction;GO:0071356//cellular response to tumor necrosis factor;GO:0009755//hormone-mediated signaling pathway;GO:0006954//inflammatory response;GO:0042445//hormone metabolic process;GO:0051460//negative regulation of corticotropin secretion;GO:0033554//cellular response to stress;GO:0071320//cellular response to cAMP;GO:0002125//maternal aggressive behavior",GO:0005515//protein binding;GO:0042277//peptide binding;GO:0051424//corticotropin-releasing hormone binding,-
139322,114,35,0,29,120,0,20,0,48,0,0,0,APOOL;apolipoprotein O-like,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
139324,0,0,0,0,0,0,2,0,69,129,10,304,HDX;highly divergent homeobox,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
139341,0,0,0,0,0,3,0,0,0,0,0,0,FUNDC1;FUN14 domain containing 1,GO:0031307//integral component of mitochondrial outer membrane;GO:0005741//mitochondrial outer membrane,GO:0001666//response to hypoxia;GO:0000422//mitochondrion degradation,GO:0005515//protein binding,-
139378,0,0,0,0,0,45,0,0,67,0,8,0,GPR112;G protein-coupled receptor 112,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
1394,156,0,0,0,12,26,21,0,24,0,0,1,CRHR1;corticotropin releasing hormone receptor 1,GO:0031982//vesicle;GO:0043025//neuronal cell body;GO:0045177//apical part of cell;GO:0005802//trans-Golgi network;GO:0031226//intrinsic component of plasma membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane;GO:0005771//multivesicular body,"GO:0048266//behavioral response to pain;GO:0071376//cellular response to corticotropin-releasing hormone stimulus;GO:2000852//regulation of corticosterone secretion;GO:0030325//adrenal gland development;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0048149//behavioral response to ethanol;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0042596//fear response;GO:0007190//activation of adenylate cyclase activity;GO:0006955//immune response;GO:0021854//hypothalamus development;GO:1901215//negative regulation of neuron death;GO:0007218//neuropeptide signaling pathway;GO:0048148//behavioral response to cocaine;GO:0035641//locomotory exploration behavior;GO:0035902//response to immobilization stress;GO:0007565//female pregnancy;GO:0051458//corticotropin secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032811//negative regulation of epinephrine secretion;GO:0030855//epithelial cell differentiation;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0060291//long-term synaptic potentiation;GO:0051867//general adaptation syndrome, behavioral process;GO:0001666//response to hypoxia;GO:0043306//positive regulation of mast cell degranulation;GO:0009755//hormone-mediated signaling pathway;GO:0007613//memory;GO:2000252//negative regulation of feeding behavior;GO:0007567//parturition;GO:0008542//visual learning",GO:0005515//protein binding;GO:0043404//corticotropin-releasing hormone receptor activity;GO:0051424//corticotropin-releasing hormone binding;GO:0001965//G-protein alpha-subunit binding;GO:0015056//corticotrophin-releasing factor receptor activity;GO:0032403//protein complex binding,K04578//Neuroactive ligand-receptor interaction;Long-term depression
139411,0,0,0,0,0,5,1,0,23,0,0,0,PTCHD1;patched domain containing 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050890//cognition;GO:0007224//smoothened signaling pathway,GO:0008158//hedgehog receptor activity,K12385//Lysosome;K14461//Fat digestion and absorption
139420,0,0,0,0,0,0,0,0,72,0,0,0,"SMEK3P;SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene",-,-,-,-
139422,0,0,0,0,0,28,0,0,9,0,0,0,"MAGEB10;melanoma antigen family B, 10",-,-,-,K12464//Neurotrophin signaling pathway
139425,0,0,0,0,0,0,0,0,15,0,0,0,DCAF8L1;DDB1 and CUL4 associated factor 8-like 1,-,-,-,-
1395,0,0,0,0,2,0,7,32,75,0,25,144,CRHR2;corticotropin releasing hormone receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum,GO:0043951//negative regulation of cAMP-mediated signaling;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0016525//negative regulation of angiogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0071376//cellular response to corticotropin-releasing hormone stimulus,GO:0005179//hormone activity;GO:0005515//protein binding;GO:0015056//corticotrophin-releasing factor receptor activity,K04579//Neuroactive ligand-receptor interaction
139562,1,0,0,0,0,0,0,0,5,0,0,0,OTUD6A;OTU deubiquitinase 6A,-,GO:0035523//protein K29-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination;GO:1990167//protein K27-linked deubiquitination;GO:0006508//proteolysis;GO:0035871//protein K11-linked deubiquitination,GO:0004843//ubiquitin-specific protease activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
139596,0,42,0,3,18,0,0,0,38,0,0,327,UPRT;uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006222//UMP biosynthetic process;GO:0007595//lactation;GO:0007565//female pregnancy;GO:0032868//response to insulin,-,K00761//Pyrimidine metabolism;Metabolic pathways
139599,0,0,0,0,0,0,51,0,0,0,0,0,"MAGEE2;melanoma antigen family E, 2",-,-,-,K12464//Neurotrophin signaling pathway
139604,80,0,0,0,0,0,0,0,29,0,12,0,"MAGEB16;melanoma antigen family B, 16",-,-,-,K12464//Neurotrophin signaling pathway
139628,0,0,0,0,0,0,0,0,11,0,0,0,FOXR2;forkhead box R2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
1397,0,0,0,0,0,0,0,1,7,0,0,0,CRIP2;cysteine-rich protein 2,GO:0031012//extracellular matrix;GO:0005938//cell cortex,GO:0030097//hemopoiesis;GO:0008284//positive regulation of cell proliferation,GO:0008270//zinc ion binding,-
139716,0,0,0,0,0,67,0,0,42,0,0,0,GAB3;GRB2-associated binding protein 3,-,GO:0030225//macrophage differentiation,-,K08091//Fc gamma R-mediated phagocytosis;Osteoclast differentiation;Chronic myeloid leukemia;Fc epsilon RI signaling pathway
139728,0,0,0,0,0,0,10,0,21,0,0,0,PNCK;pregnancy up-regulated nonubiquitous CaM kinase,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding,-
139735,0,0,0,0,0,19,0,0,2,0,0,0,ZFP92;ZFP92 zinc finger protein,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
139741,0,0,0,0,0,0,0,0,3,0,0,0,ACTRT1;actin-related protein T1,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,-,K05692//Viral myocarditis;Phototransduction - fly;Adherens junction;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Focal adhesion;Vibrio cholerae infection;Gastric acid secretion;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy
139760,0,0,0,0,0,9,13,0,11,0,8,0,GPR119;G protein-coupled receptor 119,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex,GO:0030073//insulin secretion;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0031210//phosphatidylcholine binding,-
1398,0,33,0,98,125,0,0,0,0,0,0,0,CRK;v-crk avian sarcoma virus CT10 oncogene homolog,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035020//regulation of Rac protein signal transduction;GO:0009967//positive regulation of signal transduction;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048013//ephrin receptor signaling pathway;GO:0030168//platelet activation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008286//insulin receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0032319//regulation of Rho GTPase activity;GO:0000186//activation of MAPKK activity;GO:0007596//blood coagulation,GO:0045309//protein phosphorylated amino acid binding;GO:0005515//protein binding;GO:0046875//ephrin receptor binding;GO:0042169//SH2 domain binding;GO:0005070//SH3/SH2 adaptor activity,K04438//Chemokine signaling pathway;Pathways in cancer;Bacterial invasion of epithelial cells;Insulin signaling pathway;Fc gamma R-mediated phagocytosis;Shigellosis;MAPK signaling pathway;Chronic myeloid leukemia;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;ErbB signaling pathway;Focal adhesion;Renal cell carcinoma
139804,0,0,0,0,0,0,0,0,28,0,0,0,"RBMXL3;RNA binding motif protein, X-linked-like 3",-,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K12885//Spliceosome
139818,0,0,0,12,13,23,38,0,66,0,2,0,DOCK11;dedicator of cytokinesis 11,GO:0005829//cytosol,GO:0032321//positive regulation of Rho GTPase activity;GO:0007596//blood coagulation;GO:0007264//small GTPase mediated signal transduction,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0017048//Rho GTPase binding,-
139886,0,0,0,0,14,0,4,0,13,0,0,0,"SPIN4;spindlin family, member 4",-,GO:0007276//gamete generation,-,-
1399,0,19,0,30,90,0,38,48,19,0,2,4,CRKL;v-crk avian sarcoma virus CT10 oncogene homolog-like,GO:0005829//cytosol;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome,GO:0048538//thymus development;GO:0009952//anterior/posterior pattern specification;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007254//JNK cascade;GO:0007265//Ras protein signal transduction;GO:0060017//parathyroid gland development;GO:0001568//blood vessel development;GO:0007507//heart development;GO:0009967//positive regulation of signal transduction;GO:0000186//activation of MAPKK activity;GO:0035556//intracellular signal transduction;GO:0009887//organ morphogenesis,GO:0005070//SH3/SH2 adaptor activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K04438//Pathways in cancer;Chemokine signaling pathway;Bacterial invasion of epithelial cells;Insulin signaling pathway;Fc gamma R-mediated phagocytosis;Shigellosis;MAPK signaling pathway;Chronic myeloid leukemia;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;ErbB signaling pathway;Focal adhesion;Renal cell carcinoma
14,0,5,1,0,92,0,44,29,21,0,0,8,"AAMP;angio-associated, migratory cell protein",GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0001525//angiogenesis;GO:0014909//smooth muscle cell migration;GO:0030154//cell differentiation;GO:0010595//positive regulation of endothelial cell migration,GO:0008201//heparin binding,-
140,0,0,0,0,0,0,44,50,0,0,0,0,ADORA3;adenosine A3 receptor,GO:0042629//mast cell granule;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0070257//positive regulation of mucus secretion;GO:0050729//positive regulation of inflammatory response;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0050850//positive regulation of calcium-mediated signaling;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0009611//response to wounding;GO:0002687//positive regulation of leukocyte migration;GO:0043306//positive regulation of mast cell degranulation;GO:0001973//adenosine receptor signaling pathway;GO:0002553//histamine secretion by mast cell,GO:0001609//G-protein coupled adenosine receptor activity,K04268//Neuroactive ligand-receptor interaction
1400,0,143,0,66,228,14,21,118,22,0,114,1,CRMP1;collapsin response mediator protein 1,GO:0005829//cytosol;GO:0030425//dendrite;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0006208//pyrimidine nucleobase catabolic process;GO:0006139//nucleobase-containing compound metabolic process,"GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides;GO:0005515//protein binding",K07528//Axon guidance
1401,0,0,0,0,0,4,0,0,0,0,0,0,"CRP;C-reactive protein, pentraxin-related",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0030175//filopodium;GO:0030426//growth cone,"GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0001666//response to hypoxia;GO:1900006//positive regulation of dendrite development;GO:0007568//aging;GO:0050830//defense response to Gram-positive bacterium;GO:0006954//inflammatory response;GO:2000482//regulation of interleukin-8 secretion;GO:0006958//complement activation, classical pathway;GO:0010288//response to lead ion;GO:0045471//response to ethanol;GO:0006953//acute-phase response;GO:0051258//protein polymerization;GO:0042060//wound healing;GO:0010888//negative regulation of lipid storage;GO:0071277//cellular response to calcium ion;GO:0008228//opsonization",GO:0015485//cholesterol binding;GO:0005515//protein binding;GO:0001849//complement component C1q binding;GO:0030169//low-density lipoprotein particle binding;GO:0033265//choline binding;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0046790//virion binding,K01672//Pancreatic secretion;Nitrogen metabolism;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Collecting duct acid secretion
140290,0,0,0,0,0,0,0,0,38,0,0,0,TCP10L;t-complex 10-like,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0070491//repressing transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0043621//protein self-association,-
1404,0,0,0,0,0,17,0,0,29,0,0,0,HAPLN1;hyaluronan and proteoglycan link protein 1,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion,GO:0005540//hyaluronic acid binding,-
140432,0,0,0,0,0,13,0,0,0,0,0,0,RNF113B;ring finger protein 113B,-,-,GO:0008270//zinc ion binding,-
140453,108,0,44,0,11,23,55,0,94,162,5,0,"MUC17;mucin 17, cell surface associated",GO:0016324//apical plasma membrane;GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0019725//cellular homeostasis;GO:0044267//cellular protein metabolic process,"GO:0030197//extracellular matrix constituent, lubricant activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding",K10955//Amoebiasis;Vibrio cholerae infection
140456,0,0,0,0,0,13,13,0,15,141,0,0,"ASB11;ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase",-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
140458,0,0,0,0,0,0,5,0,21,0,0,0,ASB5;ankyrin repeat and SOCS box containing 5,-,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
140459,1,353,758,393,439,0,57,972,230,89,763,0,ASB6;ankyrin repeat and SOCS box containing 6,GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
140460,0,7,1,0,13,0,0,24,25,0,0,0,ASB7;ankyrin repeat and SOCS box containing 7,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
140461,0,16,0,44,41,0,0,0,43,0,0,0,ASB8;ankyrin repeat and SOCS box containing 8,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
140462,35,0,0,0,0,0,0,0,11,0,0,0,ASB9;ankyrin repeat and SOCS box containing 9,GO:0005739//mitochondrion,GO:0045732//positive regulation of protein catabolic process;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,GO:0005515//protein binding,-
140465,0,1,1,0,2,1,0,0,4,0,21,0,"MYL6B;myosin, light chain 6B, alkali, smooth muscle and non-muscle",GO:0016459//myosin complex;GO:0005859//muscle myosin complex;GO:0016461//unconventional myosin complex;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process;GO:0006936//muscle contraction;GO:0030049//muscle filament sliding;GO:0007519//skeletal muscle tissue development,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0003774//motor activity;GO:0008307//structural constituent of muscle,K12751//Vascular smooth muscle contraction
140467,0,35,1,2,46,14,0,0,6,0,0,0,ZNF358;zinc finger protein 358,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0019827//stem cell maintenance;GO:0035115//embryonic forelimb morphogenesis;GO:0021915//neural tube development;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
140469,185,0,0,0,0,59,13,0,113,2,6,0,MYO3B;myosin IIIB,GO:0001917//photoreceptor inner segment;GO:0032426//stereocilium bundle tip;GO:0001750//photoreceptor outer segment;GO:0016459//myosin complex;GO:0005737//cytoplasm;GO:0032433//filopodium tip,GO:0051491//positive regulation of filopodium assembly;GO:0050896//response to stimulus;GO:0046777//protein autophosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0007601//visual perception,GO:0005524//ATP binding;GO:0003779//actin binding;GO:0004674//protein serine/threonine kinase activity;GO:0000146//microfilament motor activity,K08834//Phototransduction - fly
140545,0,0,0,8,0,5,0,0,7,0,14,0,RNF32;ring finger protein 32,GO:0016235//aggresome;GO:0005768//endosome,-,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
140564,41,0,0,0,1,0,10,0,15,0,0,0,"APOBEC3D;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D",GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body,GO:0070383//DNA cytosine deamination;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0010529//negative regulation of transposition;GO:0045087//innate immune response;GO:0051607//defense response to virus,"GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0008270//zinc ion binding",K01500//Atrazine degradation;Microbial metabolism in diverse environments
140576,0,0,0,12,0,0,0,60,20,0,0,0,S100A16;S100 calcium binding protein A16,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0051592//response to calcium ion,GO:0005509//calcium ion binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity,-
140578,0,0,0,0,0,40,27,0,24,0,0,0,CHODL;chondrolectin,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane,GO:0007517//muscle organ development,GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding,-
140597,0,0,0,0,6,0,0,0,14,0,0,0,TCEAL2;transcription elongation factor A (SII)-like 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
1406,0,0,0,0,0,0,20,3,12,0,2,0,CRX;cone-rod homeobox,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0007623//circadian rhythm;GO:0009887//organ morphogenesis;GO:0006351//transcription, DNA-templated;GO:0007601//visual perception;GO:0006355//regulation of transcription, DNA-templated;GO:0050896//response to stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060041//retina development in camera-type eye",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0035257//nuclear hormone receptor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043522//leucine zipper domain binding,-
140606,0,0,1,0,0,0,0,0,0,0,0,0,SELM;selenoprotein M,GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0035934//corticosterone secretion;GO:0060612//adipose tissue development;GO:0010269//response to selenium ion;GO:0035264//multicellular organism growth;GO:0042445//hormone metabolic process,-,-
140609,49,37,0,26,96,8,13,0,20,0,0,0,NEK7;NIMA-related kinase 7,GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0051225//spindle assembly;GO:0000910//cytokinesis,GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding,-
140612,35,21,0,19,0,0,33,79,33,0,12,107,ZFP28;ZFP28 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
140628,0,0,0,0,7,25,0,0,1,0,0,235,GATA5;GATA binding protein 5,GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0071773//cellular response to BMP stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0060575//intestinal epithelial cell differentiation;GO:0007596//blood coagulation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
140679,113,0,0,0,0,0,0,0,0,0,0,1,"SLC32A1;solute carrier family 32 (GABA vesicular transporter), member 1",GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0044292//dendrite terminus;GO:0005886//plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0030425//dendrite;GO:0060077//inhibitory synapse;GO:0051286//cell tip;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0044316//cone cell pedicle;GO:0044306//neuron projection terminus,GO:0015816//glycine transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0007568//aging;GO:0015812//gamma-aminobutyric acid transport,GO:0015187//glycine transmembrane transporter activity;GO:0015495//gamma-aminobutyric acid:proton symporter activity,K15015//Synaptic vesicle cycle;Retrograde endocannabinoid signaling;Morphine addiction;Nicotine addiction;GABAergic synapse
140680,99,0,0,0,9,13,0,0,4,1,0,0,C20orf96;chromosome 20 open reading frame 96,-,-,-,-
140683,0,0,0,0,0,8,0,0,16,0,8,0,"BPIFA2;BPI fold containing family A, member 2",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,-,GO:0001530//lipopolysaccharide binding,-
140685,0,1,21,13,70,16,32,51,75,83,163,0,ZBTB46;zinc finger and BTB domain containing 46,GO:0005634//nucleus,"GO:0030853//negative regulation of granulocyte differentiation;GO:0045656//negative regulation of monocyte differentiation;GO:2001200//positive regulation of dendritic cell differentiation;GO:0045650//negative regulation of macrophage differentiation;GO:0006351//transcription, DNA-templated;GO:2001199//negative regulation of dendritic cell differentiation;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
140687,0,0,0,5,26,0,39,47,39,0,0,0,GCNT7;glucosaminyl (N-acetyl) transferase family member 7,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation,GO:0008375//acetylglucosaminyltransferase activity,K00742//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
140688,0,0,0,0,0,0,87,108,25,0,11,119,NOL4L;nucleolar protein 4-like,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
140689,1,0,0,0,0,37,41,0,11,0,4,0,CBLN4;cerebellin 4 precursor,GO:0045202//synapse;GO:0030054//cell junction;GO:0005615//extracellular space,GO:0009306//protein secretion,-,K03987//Staphylococcus aureus infection;Chagas disease (American trypanosomiasis);Prion diseases;Systemic lupus erythematosus;Complement and coagulation cascades;Pertussis
140690,134,0,0,0,0,27,0,1,20,0,19,0,CTCFL;CCCTC-binding factor (zinc finger protein)-like,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006349//regulation of gene expression by genetic imprinting;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016571//histone methylation;GO:0043046//DNA methylation involved in gamete generation;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0051569//regulation of histone H3-K4 methylation",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042393//histone binding,-
140699,0,0,0,18,24,34,1,110,74,0,43,0,MROH8;maestro heat-like repeat family member 8,-,-,-,-
1407,0,0,0,0,61,0,0,0,32,2,0,0,CRY1;cryptochrome circadian clock 1,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0042593//glucose homeostasis;GO:0042754//negative regulation of circadian rhythm;GO:0009785//blue light signaling pathway;GO:0032868//response to insulin;GO:0033762//response to glucagon;GO:0018298//protein-chromophore linkage;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0006094//gluconeogenesis;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0006281//DNA repair;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006975//DNA damage induced protein phosphorylation;GO:2000001//regulation of DNA damage checkpoint;GO:0043153//entrainment of circadian clock by photoperiod;GO:0019915//lipid storage;GO:0031397//negative regulation of protein ubiquitination",GO:0003904//deoxyribodipyrimidine photo-lyase activity;GO:0003690//double-stranded DNA binding;GO:0043130//ubiquitin binding;GO:0019902//phosphatase binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0001047//core promoter binding;GO:0000989//transcription factor binding transcription factor activity;GO:0035257//nuclear hormone receptor binding;GO:0009882//blue light photoreceptor activity;GO:0003914//DNA (6-4) photolyase activity;GO:0003677//DNA binding;GO:0042826//histone deacetylase binding;GO:0019901//protein kinase binding,K02295//Circadian rhythm - mammal
140700,48,1,41,0,0,0,0,94,37,43,36,0,SAMD10;sterile alpha motif domain containing 10,-,-,-,-
140701,0,0,82,8,22,0,0,45,0,0,61,1,ABHD16B;abhydrolase domain containing 16B,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
140706,0,0,0,0,0,0,30,33,23,0,0,0,CCM2L;cerebral cavernous malformation 2-like,-,-,-,-
140707,0,0,0,0,0,0,0,0,0,46,0,0,BRI3BP;BRI3 binding protein,GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,K01907//Butanoate metabolism
140710,0,15,0,6,17,46,14,88,34,0,0,0,"SOGA1;suppressor of glucose, autophagy associated 1",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0010506//regulation of autophagy;GO:0008286//insulin receptor signaling pathway;GO:0045721//negative regulation of gluconeogenesis,-,K06102//Tight junction
140711,0,24,0,7,36,0,0,0,0,94,0,0,TLDC2;TBC/LysM-associated domain containing 2,-,-,-,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;K12587//RNA degradation
140730,134,0,0,0,0,0,37,58,18,73,6,0,RIMS4;regulating synaptic membrane exocytosis 4,GO:0030054//cell junction;GO:0097060//synaptic membrane;GO:0048786//presynaptic active zone,GO:0006836//neurotransmitter transport;GO:0042391//regulation of membrane potential;GO:0006887//exocytosis,GO:0044325//ion channel binding,-
140733,0,0,0,5,31,0,0,0,58,0,24,0,MACROD2;MACRO domain containing 2,GO:0005634//nucleus,GO:0007420//brain development;GO:0042278//purine nucleoside metabolic process;GO:0051725//protein de-ADP-ribosylation;GO:0006974//cellular response to DNA damage stimulus,"GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019213//deacetylase activity",-
140735,0,27,1,3,45,15,0,0,0,0,0,0,"DYNLL2;dynein, light chain, LC8-type 2",GO:0005634//nucleus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0030286//dynein complex;GO:0005813//centrosome;GO:0016459//myosin complex;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0007017//microtubule-based process;GO:0008152//metabolic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006810//transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006915//apoptotic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,GO:0008092//cytoskeletal protein binding;GO:0003774//motor activity,K10418//Vasopressin-regulated water reabsorption
140738,0,0,0,0,0,0,0,0,16,97,0,0,TMEM37;transmembrane protein 37,GO:0016021//integral component of membrane,GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport,GO:0005262//calcium channel activity;GO:0005244//voltage-gated ion channel activity,-
140739,0,30,1,38,118,16,10,0,72,0,0,0,UBE2F;ubiquitin-conjugating enzyme E2F (putative),-,GO:0045116//protein neddylation,GO:0005515//protein binding;GO:0019788//NEDD8 ligase activity;GO:0005524//ATP binding,K10687//Ubiquitin mediated proteolysis
140766,0,0,0,0,10,30,0,0,27,0,8,0,"ADAMTS14;ADAM metallopeptidase with thrombospondin type 1 motif, 14",GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0030574//collagen catabolic process;GO:0030199//collagen fibril organization;GO:0030198//extracellular matrix organization,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
140767,0,0,0,0,0,4,0,0,10,0,0,0,NRSN1;neurensin 1,GO:0043005//neuron projection;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0030133//transport vesicle;GO:0043025//neuronal cell body;GO:0030426//growth cone,GO:0007399//nervous system development,-,-
140775,198,73,0,25,33,7,0,0,6,0,23,0,"SMCR8;Smith-Magenis syndrome chromosome region, candidate 8",GO:0005634//nucleus;GO:0005730//nucleolus,-,-,K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K03165//Homologous recombination;Fanconi anemia pathway
1408,0,34,0,0,2,0,20,0,82,32,5,0,CRY2;cryptochrome circadian clock 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005576//extracellular region,"GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0018298//protein-chromophore linkage;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0042752//regulation of circadian rhythm;GO:0000719//photoreactive repair;GO:0007623//circadian rhythm;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043153//entrainment of circadian clock by photoperiod;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0042754//negative regulation of circadian rhythm;GO:0042593//glucose homeostasis;GO:2000118//regulation of sodium-dependent phosphate transport;GO:0009785//blue light signaling pathway",GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0019902//phosphatase binding;GO:0005515//protein binding;GO:0003904//deoxyribodipyrimidine photo-lyase activity;GO:0043130//ubiquitin binding;GO:0003684//damaged DNA binding;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0071949//FAD binding;GO:0003914//DNA (6-4) photolyase activity;GO:0009882//blue light photoreceptor activity;GO:0000989//transcription factor binding transcription factor activity,K02295//Circadian rhythm - mammal
140803,0,0,0,0,0,0,0,59,16,0,8,3,"TRPM6;transient receptor potential cation channel, subfamily M, member 6",GO:0016324//apical plasma membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006468//protein phosphorylation;GO:0009636//response to toxic substance;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0034220//ion transmembrane transport,GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04981//Mineral absorption
140807,65,0,0,0,0,23,5,64,4,0,1,0,KRT72;keratin 72,GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,-,GO:0005198//structural molecule activity,-
140809,0,23,0,10,44,20,0,1,12,0,0,0,SRXN1;sulfiredoxin 1,GO:0005829//cytosol,GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process,"GO:0005524//ATP binding;GO:0016667//oxidoreductase activity, acting on a sulfur group of donors;GO:0032542//sulfiredoxin activity",-
140823,0,19,0,1,13,0,0,141,6,0,69,1,ROMO1;reactive oxygen species modulator 1,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0008284//positive regulation of cell proliferation;GO:0042742//defense response to bacterium;GO:0001302//replicative cell aging;GO:0034614//cellular response to reactive oxygen species;GO:2000379//positive regulation of reactive oxygen species metabolic process,-,-
140825,0,0,0,0,4,0,0,0,0,0,0,0,NEURL2;neuralized E3 ubiquitin protein ligase 2,GO:0005927//muscle tendon junction;GO:0030891//VCB complex,GO:0045214//sarcomere organization;GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
140831,0,0,0,1,0,0,0,0,28,0,0,315,"ZSWIM3;zinc finger, SWIM-type containing 3",-,-,GO:0008270//zinc ion binding,-
140834,59,0,0,0,0,0,0,0,29,0,0,0,C20orf62;chromosome 20 open reading frame 62,-,-,-,-
140836,0,0,0,0,0,0,26,0,0,0,0,0,BANF2;barrier to autointegration factor 2,GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0003677//DNA binding,-
140838,0,0,0,14,0,8,26,0,27,0,14,0,NANP;N-acetylneuraminic acid phosphatase,-,GO:0046380//N-acetylneuraminate biosynthetic process;GO:0006045//N-acetylglucosamine biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0016311//dephosphorylation,GO:0050124//N-acylneuraminate-9-phosphatase activity,K01097//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Metabolic pathways
140850,0,0,0,0,0,0,0,0,12,0,0,0,"DEFB127;defensin, beta 127",GO:0005576//extracellular region,GO:0042742//defense response to bacterium;GO:0045087//innate immune response,-,-
140856,0,0,0,0,0,0,0,0,14,0,0,0,SCP2D1;SCP2 sterol-binding domain containing 1,-,-,-,K12405//Peroxisome;Primary bile acid biosynthesis;Metabolic pathways
140862,110,0,0,0,0,0,0,15,7,0,0,0,"ISM1;isthmin 1, angiogenesis inhibitor",GO:0005576//extracellular region,-,-,K04659//TGF-beta signaling pathway;Focal adhesion;Bladder cancer;p53 signaling pathway;ECM-receptor interaction;Phagosome;Malaria
140870,0,0,0,0,0,0,3,0,1,0,0,0,WFDC6;WAP four-disulfide core domain 6,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,-
140873,0,0,0,2,0,0,21,0,33,115,0,0,C20orf173;chromosome 20 open reading frame 173,-,-,-,K00780//Glycosaminoglycan biosynthesis - keratan sulfate;Glycosphingolipid biosynthesis - globo series;Glycosphingolipid biosynthesis - ganglio series;Mucin type O-Glycan biosynthesis;Metabolic pathways
140876,66,0,0,0,0,27,1,1,25,0,6,2,"FAM65C;family with sequence similarity 65, member C",-,-,-,-
140880,0,0,0,0,0,0,0,0,0,0,1,0,CST11;cystatin 11,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010951//negative regulation of endopeptidase activity;GO:0042742//defense response to bacterium,GO:0004869//cysteine-type endopeptidase inhibitor activity,-
140881,0,0,0,0,0,0,0,0,17,0,0,0,"DEFB129;defensin, beta 129",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
140883,45,0,0,0,0,17,0,49,59,0,0,0,ZNF280B;zinc finger protein 280B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
140885,59,0,0,0,0,71,33,69,0,0,23,0,SIRPA;signal-regulatory protein alpha,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007596//blood coagulation;GO:0007155//cell adhesion;GO:0050900//leukocyte migration,GO:0017124//SH3 domain binding,K06551//Osteoclast differentiation
140886,6,0,0,0,0,0,18,0,29,0,0,0,"PABPC5;poly(A) binding protein, cytoplasmic 5",GO:0005759//mitochondrial matrix,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K13126//RNA degradation;mRNA surveillance pathway;RNA transport
140890,0,54,21,30,25,1,30,0,106,0,12,0,SREK1;splicing regulatory glutamine/lysine-rich protein 1,GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
140893,0,0,0,0,12,54,0,0,15,0,7,0,RBBP8NL;RBBP8 N-terminal like,GO:0005615//extracellular space,-,-,-
140894,107,0,0,0,0,7,0,0,13,0,0,0,CNBD2;cyclic nucleotide binding domain containing 2,-,-,-,K07376//Gap junction;Long-term depression;Vascular smooth muscle contraction;Olfactory transduction;Salivary secretion;K08014//Serotonergic synapse;Long-term potentiation;Leukocyte transendothelial migration;K04351//Leukocyte transendothelial migration
1409,0,0,0,0,0,0,17,0,17,0,0,0,"CRYAA;crystallin, alpha A",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0051260//protein homooligomerization;GO:0042026//protein refolding;GO:0007601//visual perception;GO:0032387//negative regulation of intracellular transport;GO:0043066//negative regulation of apoptotic process;GO:0050896//response to stimulus,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005212//structural constituent of eye lens;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding,K09541//Protein processing in endoplasmic reticulum
140901,0,18,23,15,7,0,51,70,48,0,17,0,STK35;serine/threonine kinase 35,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
140902,0,0,0,0,0,0,16,1,0,0,0,0,R3HDML;R3H domain containing-like,GO:0005576//extracellular region,GO:0010466//negative regulation of peptidase activity,GO:0030414//peptidase inhibitor activity,K02330//HTLV-I infection;Base excision repair;K00747//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
140947,0,0,0,0,0,0,5,0,11,0,8,0,C5orf20;chromosome 5 open reading frame 20,GO:0005634//nucleus,-,-,-
141,102,6,64,2,0,0,0,0,25,141,5,292,ADPRH;ADP-ribosylarginine hydrolase,-,GO:0051725//protein de-ADP-ribosylation;GO:0006464//cellular protein modification process,GO:0000287//magnesium ion binding;GO:0003875//ADP-ribosylarginine hydrolase activity,-
1410,0,87,0,5,37,11,0,0,1,0,0,0,"CRYAB;crystallin, alpha B",GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0032432//actin filament bundle;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,GO:0031109//microtubule polymerization or depolymerization;GO:0001666//response to hypoxia;GO:0071480//cellular response to gamma radiation;GO:0007517//muscle organ development;GO:0006936//muscle contraction;GO:0007568//aging;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0006006//glucose metabolic process;GO:0032355//response to estradiol;GO:0010941//regulation of cell death;GO:0006457//protein folding;GO:0042542//response to hydrogen peroxide;GO:0030308//negative regulation of cell growth;GO:0051403//stress-activated MAPK cascade;GO:0032387//negative regulation of intracellular transport;GO:0043066//negative regulation of apoptotic process;GO:0060561//apoptotic process involved in morphogenesis;GO:0051260//protein homooligomerization;GO:0010629//negative regulation of gene expression;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002088//lens development in camera-type eye;GO:0007021//tubulin complex assembly,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0005212//structural constituent of eye lens;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0051082//unfolded protein binding,K09542//Protein processing in endoplasmic reticulum
1411,74,0,0,0,0,0,0,0,0,0,0,291,"CRYBA1;crystallin, beta A1",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0002088//lens development in camera-type eye;GO:0007601//visual perception,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005212//structural constituent of eye lens,K01886//Metabolic pathways;ABC transporters;Aminoacyl-tRNA biosynthesis;Ribosome
1412,0,0,0,0,0,0,0,2,16,0,0,0,"CRYBA2;crystallin, beta A2",-,GO:0002088//lens development in camera-type eye,GO:0005212//structural constituent of eye lens;GO:0042803//protein homodimerization activity,K01886//Aminoacyl-tRNA biosynthesis;ABC transporters;Metabolic pathways;Ribosome
1413,0,0,0,0,0,0,0,0,19,0,0,0,"CRYBA4;crystallin, beta A4",-,GO:0007601//visual perception;GO:0043010//camera-type eye development,GO:0005212//structural constituent of eye lens,K01886//Ribosome;Metabolic pathways;ABC transporters;Aminoacyl-tRNA biosynthesis
1414,0,22,93,0,0,0,0,79,0,0,0,0,"CRYBB1;crystallin, beta B1",-,GO:0007601//visual perception,GO:0005212//structural constituent of eye lens,K01886//Metabolic pathways;Aminoacyl-tRNA biosynthesis;ABC transporters;Ribosome
1415,0,0,0,0,0,0,15,0,5,0,0,0,"CRYBB2;crystallin, beta B2",-,GO:0050896//response to stimulus;GO:0043010//camera-type eye development;GO:0007601//visual perception,GO:0005212//structural constituent of eye lens;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K01886//Metabolic pathways;ABC transporters;Aminoacyl-tRNA biosynthesis;Ribosome
1416,0,0,0,0,0,2,0,0,0,0,0,0,"CRYBB2P1;crystallin, beta B2 pseudogene 1",-,-,-,K04257//Olfactory transduction;K00543//Metabolic pathways;Tryptophan metabolism
1417,0,0,0,0,0,0,5,0,0,0,0,0,"CRYBB3;crystallin, beta B3",-,GO:0007601//visual perception,GO:0005212//structural constituent of eye lens,K01886//Ribosome;Aminoacyl-tRNA biosynthesis;ABC transporters;Metabolic pathways
1418,0,0,0,0,0,3,0,2,0,0,0,0,"CRYGA;crystallin, gamma A",-,GO:0007601//visual perception;GO:0002088//lens development in camera-type eye,GO:0005212//structural constituent of eye lens,K01886//Ribosome;Metabolic pathways;Aminoacyl-tRNA biosynthesis;ABC transporters
142,0,35,2,46,143,0,1,132,63,96,6,0,PARP1;poly (ADP-ribose) polymerase 1,GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0016020//membrane,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000723//telomere maintenance;GO:0030225//macrophage differentiation;GO:0032869//cellular response to insulin stimulus;GO:0070212//protein poly-ADP-ribosylation;GO:0010467//gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023019//signal transduction involved in regulation of gene expression;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042769//DNA damage response, detection of DNA damage;GO:0006471//protein ADP-ribosylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0040009//regulation of growth rate;GO:0016540//protein autoprocessing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006284//base-excision repair;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0006302//double-strand break repair;GO:0006281//DNA repair",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0047485//protein N-terminus binding;GO:0070412//R-SMAD binding;GO:0019899//enzyme binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0042802//identical protein binding;GO:0051287//NAD binding;GO:0003677//DNA binding,K10798//NF-kappa B signaling pathway;Base excision repair
1421,0,0,0,0,0,0,0,0,31,0,0,0,"CRYGD;crystallin, gamma D",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0034614//cellular response to reactive oxygen species;GO:0007601//visual perception;GO:0070306//lens fiber cell differentiation;GO:0002088//lens development in camera-type eye,GO:0005515//protein binding;GO:0005212//structural constituent of eye lens,K01886//Ribosome;Aminoacyl-tRNA biosynthesis;ABC transporters;Metabolic pathways
142678,0,40,83,36,16,10,0,294,50,0,95,484,MIB2;mindbomb E3 ubiquitin protein ligase 2,GO:0005769//early endosome;GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0003779//actin binding,-
142679,0,0,0,0,0,0,19,0,40,0,0,0,DUSP19;dual specificity phosphatase 19,GO:0005737//cytoplasm,GO:0000188//inactivation of MAPK activity;GO:0043508//negative regulation of JUN kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0043507//positive regulation of JUN kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0046329//negative regulation of JNK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0006469//negative regulation of protein kinase activity;GO:0045860//positive regulation of protein kinase activity;GO:0007254//JNK cascade,GO:0004725//protein tyrosine phosphatase activity;GO:0004860//protein kinase inhibitor activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0030295//protein kinase activator activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0008579//JUN kinase phosphatase activity;GO:0005078//MAP-kinase scaffold activity,-
142680,0,1,52,0,0,0,18,0,1,0,19,0,"SLC34A3;solute carrier family 34 (type II sodium/phosphate contransporter), member 3",GO:0016324//apical plasma membrane;GO:0005903//brush border;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0035435//phosphate ion transmembrane transport;GO:0044341//sodium-dependent phosphate transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:0030643//cellular phosphate ion homeostasis;GO:0035725//sodium ion transmembrane transport;GO:0006817//phosphate ion transport;GO:0006811//ion transport,GO:0005436//sodium:phosphate symporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity,K14683//Mineral absorption
142683,0,0,1,0,6,18,0,0,24,0,0,558,ITLN2;intelectin 2,GO:0005576//extracellular region,-,GO:0030246//carbohydrate binding,-
142684,0,0,1,8,0,0,0,0,40,0,34,0,"RAB40A;RAB40A, member RAS oncogene family",GO:0005886//plasma membrane,GO:0016567//protein ubiquitination;GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
142685,0,0,0,0,0,26,41,0,36,0,0,0,ASB15;ankyrin repeat and SOCS box containing 15,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
142686,0,27,2,63,79,29,9,0,42,0,12,0,ASB14;ankyrin repeat and SOCS box containing 14,-,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
142689,0,0,0,0,0,0,0,35,0,0,0,1,ASB12;ankyrin repeat and SOCS box containing 12,-,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
1427,56,0,0,0,0,0,0,0,0,0,0,0,"CRYGS;crystallin, gamma S",-,GO:0002009//morphogenesis of an epithelium;GO:0002088//lens development in camera-type eye,GO:0005212//structural constituent of eye lens,K01886//Ribosome;ABC transporters;Aminoacyl-tRNA biosynthesis;Metabolic pathways
1428,0,0,0,24,43,0,0,82,24,0,1,0,"CRYM;crystallin, mu",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0070327//thyroid hormone transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042403//thyroid hormone metabolic process;GO:0007605//sensory perception of sound;GO:0055114//oxidation-reduction process,GO:0042803//protein homodimerization activity;GO:0047127//thiomorpholine-carboxylate dehydrogenase activity;GO:0050661//NADP binding;GO:0070324//thyroid hormone binding;GO:0003714//transcription corepressor activity,-
142827,0,0,0,0,0,0,0,49,20,165,1,0,ACSM6;acyl-CoA synthetase medium-chain family member 6,GO:0005739//mitochondrion,GO:0006631//fatty acid metabolic process,GO:0005524//ATP binding;GO:0047760//butyrate-CoA ligase activity;GO:0005525//GTP binding;GO:0046872//metal ion binding,K01896//Butanoate metabolism;Lipoic acid metabolism;Metabolic pathways
142891,94,0,0,0,37,0,9,6,84,0,0,0,SAMD8;sterile alpha motif domain containing 8,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006686//sphingomyelin biosynthetic process;GO:2000303//regulation of ceramide biosynthetic process;GO:0046513//ceramide biosynthetic process,GO:0016740//transferase activity,K04714//Metabolic pathways;Sphingolipid metabolism
1429,203,137,43,184,244,17,0,29,26,0,230,1,"CRYZ;crystallin, zeta (quinone reductase)",GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0007601//visual perception;GO:0051289//protein homotetramerization;GO:0055114//oxidation-reduction process;GO:0042178//xenobiotic catabolic process,GO:0003730//mRNA 3'-UTR binding;GO:0070402//NADPH binding;GO:0008270//zinc ion binding;GO:0003960//NADPH:quinone reductase activity;GO:0070404//NADH binding,K00344//Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Metabolic pathways;Tyrosine metabolism;Naphthalene degradation;Chloroalkane and chloroalkene degradation;Fatty acid metabolism
142910,70,0,0,0,0,7,1,0,34,0,0,0,"LIPJ;lipase, family member J",-,GO:0016042//lipid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds",K14452//Fat digestion and absorption;Metabolic pathways;Glycerolipid metabolism
142913,0,0,0,0,0,0,0,0,2,0,0,0,CFL1P1;cofilin 1 (non-muscle) pseudogene 1,-,-,-,K05765//Regulation of actin cytoskeleton;Axon guidance;Pertussis;Fc gamma R-mediated phagocytosis
142940,0,2,0,26,67,13,65,0,51,25,0,0,TRUB1;TruB pseudouridine (psi) synthase family member 1,-,GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing,GO:0009982//pseudouridine synthase activity;GO:0003723//RNA binding,-
143,76,0,0,32,108,16,12,0,43,36,13,0,"PARP4;poly (ADP-ribose) polymerase family, member 4",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex,GO:0006810//transport;GO:0008219//cell death;GO:0042493//response to drug;GO:0006464//cellular protein modification process;GO:0006974//cellular response to DNA damage stimulus;GO:0006954//inflammatory response;GO:0006471//protein ADP-ribosylation;GO:0006281//DNA repair,GO:0019899//enzyme binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0003677//DNA binding,K10798//NF-kappa B signaling pathway;Base excision repair
143098,0,0,0,59,82,24,62,11,39,0,0,0,"MPP7;membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)",GO:0030054//cell junction;GO:0005923//tight junction;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0005739//mitochondrion;GO:0005912//adherens junction,GO:0030010//establishment of cell polarity;GO:0071896//protein localization to adherens junction;GO:0070830//tight junction assembly;GO:0009967//positive regulation of signal transduction;GO:0031334//positive regulation of protein complex assembly,GO:0035591//signaling adaptor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0032947//protein complex scaffold;GO:0019904//protein domain specific binding,K06091//Tight junction
1431,0,68,1,29,196,0,1,10,29,0,0,0,CS;citrate synthase,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005759//mitochondrial matrix,GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044262//cellular carbohydrate metabolic process,GO:0004108//citrate (Si)-synthase activity;GO:0044822//poly(A) RNA binding,K01647//Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Methane metabolism;Glyoxylate and dicarboxylate metabolism;Pyruvate metabolism;ABC transporters;Citrate cycle (TCA cycle);Metabolic pathways
143162,0,0,0,0,1,16,25,2,47,112,0,0,FRMPD2;FERM and PDZ domain containing 2,GO:0005923//tight junction;GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0070830//tight junction assembly,GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding,-
143187,0,3,0,2,13,0,0,0,7,0,0,0,VTI1A;vesicle transport through interaction with t-SNAREs 1A,GO:0005794//Golgi apparatus;GO:0031201//SNARE complex;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,"GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport",GO:0005484//SNAP receptor activity,K08493//SNARE interactions in vesicular transport
1432,0,39,1,15,50,0,29,0,41,0,20,0,MAPK14;mitogen-activated protein kinase 14,GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000187//activation of MAPK activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0014835//myoblast differentiation involved in skeletal muscle regeneration;GO:0000902//cell morphogenesis;GO:0010831//positive regulation of myotube differentiation;GO:0006915//apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006928//cellular component movement;GO:0045087//innate immune response;GO:0071479//cellular response to ionizing radiation;GO:0000077//DNA damage checkpoint;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0034146//toll-like receptor 5 signaling pathway;GO:0090400//stress-induced premature senescence;GO:1901741//positive regulation of myoblast fusion;GO:0042307//positive regulation of protein import into nucleus;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007596//blood coagulation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0019395//fatty acid oxidation;GO:0051149//positive regulation of muscle cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002062//chondrocyte differentiation;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0038066//p38MAPK cascade;GO:0042770//signal transduction in response to DNA damage;GO:0016071//mRNA metabolic process;GO:0042692//muscle cell differentiation;GO:0018105//peptidyl-serine phosphorylation;GO:0030316//osteoclast differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0007265//Ras protein signal transduction;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045648//positive regulation of erythrocyte differentiation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0035556//intracellular signal transduction;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010467//gene expression;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0071222//cellular response to lipopolysaccharide;GO:0016070//RNA metabolic process;GO:0030168//platelet activation;GO:0006935//chemotaxis;GO:0032495//response to muramyl dipeptide;GO:0007519//skeletal muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0001502//cartilage condensation",GO:0005515//protein binding;GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0051525//NFAT protein binding;GO:0005524//ATP binding,K04441//Neurotrophin signaling pathway;Hepatitis C;Toxoplasmosis;Osteoclast differentiation;Leishmaniasis;VEGF signaling pathway;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);NOD-like receptor signaling pathway;Shigellosis;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;T cell receptor signaling pathway;MAPK signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;Salmonella infection;GnRH signaling pathway;Dopaminergic synapse;MAPK signaling pathway - yeast;Progesterone-mediated oocyte maturation;Influenza A;Toll-like receptor signaling pathway;Tuberculosis;Pertussis
143241,0,0,0,0,0,0,18,0,12,0,3,0,DYDC1;DPY30 domain containing 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K09057//Circadian rhythm - fly;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
143244,50,0,0,0,0,5,0,0,0,0,0,0,EIF5AL1;eukaryotic translation initiation factor 5A-like 1,GO:0005643//nuclear pore;GO:0005789//endoplasmic reticulum membrane,GO:0006452//translational frameshifting;GO:0045905//positive regulation of translational termination;GO:0045901//positive regulation of translational elongation;GO:0015031//protein transport;GO:0008612//peptidyl-lysine modification to peptidyl-hypusine;GO:0051028//mRNA transport,GO:0003746//translation elongation factor activity;GO:0043022//ribosome binding,-
143279,0,0,0,31,1,0,0,65,94,145,8,0,HECTD2;HECT domain containing E3 ubiquitin protein ligase 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
143282,0,0,0,1,1,0,13,0,1,0,14,0,FGFBP3;fibroblast growth factor binding protein 3,GO:0005576//extracellular region;GO:0031012//extracellular matrix,GO:0043117//positive regulation of vascular permeability;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway,GO:0008201//heparin binding;GO:0017134//fibroblast growth factor binding,-
143379,0,0,0,0,0,0,0,0,9,0,0,0,C10orf82;chromosome 10 open reading frame 82,-,-,-,-
143384,0,0,0,36,182,24,0,13,64,170,0,0,"CACUL1;CDK2-associated, cullin domain 1",GO:0031461//cullin-RING ubiquitin ligase complex,GO:0000082//G1/S transition of mitotic cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045860//positive regulation of protein kinase activity,GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
1434,74,0,1,26,17,0,0,125,47,118,0,0,CSE1L;CSE1 chromosome segregation 1-like (yeast),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0008283//cell proliferation;GO:0006611//protein export from nucleus;GO:0006915//apoptotic process,GO:0008536//Ran GTPase binding;GO:0005515//protein binding;GO:0008262//importin-alpha export receptor activity,-
143425,0,0,0,0,0,48,25,0,16,5,0,10,SYT9;synaptotagmin IX,GO:0031045//dense core granule;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane,GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0006810//transport;GO:0050796//regulation of insulin secretion,GO:0005215//transporter activity;GO:0046872//metal ion binding;GO:0042802//identical protein binding,K15290//Synaptic vesicle cycle
143458,0,0,1,8,31,0,37,0,18,0,0,0,LDLRAD3;low density lipoprotein receptor class A domain containing 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0070613//regulation of protein processing;GO:0006898//receptor-mediated endocytosis,GO:0001540//beta-amyloid binding,K06233//Hedgehog signaling pathway
143471,0,0,0,0,0,16,0,0,0,0,0,0,"PSMA8;proteasome (prosome, macropain) subunit, alpha type, 8","GO:1990111//spermatoproteasome complex;GO:0005829//cytosol;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus","GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0006915//apoptotic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0044281//small molecule metabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle",GO:0004298//threonine-type endopeptidase activity,K02731//Proteasome
143496,0,0,0,0,0,27,0,0,10,0,0,0,"OR52B4;olfactory receptor, family 52, subfamily B, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050890//cognition;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
1435,1,0,0,0,0,0,58,86,25,0,1,308,CSF1;colony stimulating factor 1 (macrophage),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0043235//receptor complex,GO:0048873//homeostasis of number of cells within a tissue;GO:0010628//positive regulation of gene expression;GO:0030335//positive regulation of cell migration;GO:0045672//positive regulation of osteoclast differentiation;GO:0001954//positive regulation of cell-matrix adhesion;GO:0030225//macrophage differentiation;GO:0008283//cell proliferation;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0032270//positive regulation of cellular protein metabolic process;GO:0045651//positive regulation of macrophage differentiation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0042117//monocyte activation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045087//innate immune response;GO:0060611//mammary gland fat development;GO:0001503//ossification;GO:0008284//positive regulation of cell proliferation;GO:0060763//mammary duct terminal end bud growth;GO:0003006//developmental process involved in reproduction;GO:0030278//regulation of ossification;GO:0030097//hemopoiesis;GO:0030316//osteoclast differentiation;GO:0002158//osteoclast proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0006954//inflammatory response;GO:0045657//positive regulation of monocyte differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0030154//cell differentiation;GO:0042476//odontogenesis,GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005125//cytokine activity,K05453//Osteoclast differentiation;Rheumatoid arthritis;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction
143501,0,0,0,0,0,1,0,0,6,0,0,0,C11orf40;chromosome 11 open reading frame 40,-,-,-,-
143502,0,0,0,0,0,0,0,0,25,0,0,0,"OR52I2;olfactory receptor, family 52, subfamily I, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
143503,0,0,0,0,20,0,10,0,59,0,0,0,"OR51E1;olfactory receptor, family 51, subfamily E, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
143570,0,49,79,197,101,0,10,116,44,6,168,0,XRRA1;X-ray radiation resistance associated 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010165//response to X-ray,-,K10168//Salmonella infection;Toll-like receptor signaling pathway;Legionellosis;Pathogenic Escherichia coli infection;K12947//Protein export;K06261//Hematopoietic cell lineage;ECM-receptor interaction
1436,0,0,75,9,15,13,19,0,70,0,32,318,CSF1R;colony stimulating factor 1 receptor,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0006954//inflammatory response;GO:0071345//cellular response to cytokine stimulus;GO:0060603//mammary gland duct morphogenesis;GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0030316//osteoclast differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0007275//multicellular organismal development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0031529//ruffle organization;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0045217//cell-cell junction maintenance;GO:0030335//positive regulation of cell migration;GO:0090197//positive regulation of chemokine secretion;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0045124//regulation of bone resorption;GO:0030224//monocyte differentiation;GO:0030097//hemopoiesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0046488//phosphatidylinositol metabolic process;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:2000147//positive regulation of cell motility;GO:0008283//cell proliferation;GO:0030225//macrophage differentiation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008360//regulation of cell shape,GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0005011//macrophage colony-stimulating factor receptor activity;GO:0019955//cytokine binding,K05090//Endocytosis;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Pathways in cancer;Osteoclast differentiation;Transcriptional misregulation in cancer
143630,0,35,0,0,15,20,0,0,0,0,0,0,UBQLNL;ubiquilin-like,-,-,-,K04523//Protein processing in endoplasmic reticulum
143662,0,0,0,0,2,3,0,0,0,0,0,0,"MUC15;mucin 15, cell surface associated",GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen,GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,-,-
143678,0,0,0,0,0,0,0,0,11,0,0,0,C11orf94;chromosome 11 open reading frame 94,GO:0005576//extracellular region,-,-,-
143684,0,0,0,0,0,0,0,0,17,0,6,0,"FAM76B;family with sequence similarity 76, member B",GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0031965//nuclear membrane,-,-,-
143686,0,0,0,33,81,13,0,0,0,0,6,0,SESN3;sestrin 3,GO:0005634//nucleus,GO:0042593//glucose homeostasis;GO:1901031//regulation of response to reactive oxygen species;GO:0051896//regulation of protein kinase B signaling;GO:0032868//response to insulin,-,K10141//p53 signaling pathway
143689,80,0,0,0,0,6,18,0,28,0,0,0,PIWIL4;piwi-like RNA-mediated gene silencing 4,GO:0005634//nucleus;GO:0043186//P granule;GO:0005737//cytoplasm;GO:0071547//piP-body,GO:0043046//DNA methylation involved in gamete generation;GO:0034587//piRNA metabolic process;GO:0031047//gene silencing by RNA;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006417//regulation of translation;GO:0007126//meiotic nuclear division,GO:0034584//piRNA binding,K02156//Dorso-ventral axis formation
1437,0,0,0,0,0,0,10,0,4,0,7,0,CSF2;colony stimulating factor 2 (granulocyte-macrophage),GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0032747//positive regulation of interleukin-23 production;GO:0008284//positive regulation of cell proliferation;GO:0042116//macrophage activation;GO:0097028//dendritic cell differentiation;GO:0043011//myeloid dendritic cell differentiation;GO:0042045//epithelial fluid transport;GO:0006955//immune response;GO:0010628//positive regulation of gene expression;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0001892//embryonic placenta development;GO:0071222//cellular response to lipopolysaccharide;GO:0071803//positive regulation of podosome assembly;GO:0045918//negative regulation of cytolysis;GO:0045740//positive regulation of DNA replication;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0005129//granulocyte macrophage colony-stimulating factor receptor binding;GO:0008083//growth factor activity,K05427//Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Amoebiasis;Jak-STAT signaling pathway;Rheumatoid arthritis;Salmonella infection;HTLV-I infection;Fc epsilon RI signaling pathway;Transcriptional misregulation in cancer
1438,2,0,1,0,0,0,0,0,0,0,0,0,"CSF2RA;colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0019221//cytokine-mediated signaling pathway;GO:0045471//response to ethanol,GO:0004896//cytokine receptor activity;GO:0004872//receptor activity,K05066//Pathways in cancer;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
143872,0,1,0,8,6,30,0,0,42,62,0,0,ARHGAP42;Rho GTPase activating protein 42,GO:0005622//intracellular,GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K13736//Bacterial invasion of epithelial cells
143879,101,87,44,31,121,6,0,91,35,0,59,1,KBTBD3;kelch repeat and BTB (POZ) domain containing 3,-,-,-,-
143884,0,0,0,8,25,55,0,0,67,0,5,0,"CWF19L2;CWF19-like 2, cell cycle control (S. pombe)",-,GO:0008152//metabolic process,GO:0003824//catalytic activity,K12893//Herpes simplex infection;Spliceosome
143888,1,0,0,29,80,18,4,0,35,0,2,47,KDELC2;KDEL (Lys-Asp-Glu-Leu) containing 2,GO:0005788//endoplasmic reticulum lumen,-,-,K13667//Other types of O-glycan biosynthesis
1439,0,0,18,0,0,4,0,0,52,0,1,0,"CSF2RB;colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030526//granulocyte macrophage colony-stimulating factor receptor complex,GO:0038156//interleukin-3-mediated signaling pathway;GO:0036016//cellular response to interleukin-3;GO:0007585//respiratory gaseous exchange;GO:0032496//response to lipopolysaccharide;GO:0007165//signal transduction;GO:0038043//interleukin-5-mediated signaling pathway,GO:0004914//interleukin-5 receptor activity;GO:0005515//protein binding;GO:0004912//interleukin-3 receptor activity;GO:0004872//receptor activity,K04738//Apoptosis;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
143903,0,0,0,0,0,16,0,0,0,0,0,0,LAYN;layilin,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0001726//ruffle;GO:0005925//focal adhesion,-,GO:0005540//hyaluronic acid binding;GO:0030246//carbohydrate binding,-
143941,0,48,0,0,11,0,0,33,0,0,12,0,TTC36;tetratricopeptide repeat domain 36,-,-,-,-
1440,0,0,0,0,0,5,0,0,24,148,0,2,CSF3;colony stimulating factor 3 (granulocyte),GO:0005615//extracellular space,GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0019221//cytokine-mediated signaling pathway;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007275//multicellular organismal development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071345//cellular response to cytokine stimulus;GO:0030838//positive regulation of actin filament polymerization;GO:0071222//cellular response to lipopolysaccharide;GO:0042993//positive regulation of transcription factor import into nucleus;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0006955//immune response;GO:0032092//positive regulation of protein binding;GO:1901215//negative regulation of neuron death;GO:0030851//granulocyte differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0008284//positive regulation of cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation,GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005130//granulocyte colony-stimulating factor receptor binding;GO:0019899//enzyme binding,K05423//Malaria;Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage
144097,0,0,0,0,1,0,0,0,8,0,0,0,C11orf84;chromosome 11 open reading frame 84,-,-,-,-
1441,0,0,0,0,0,0,27,0,19,9,19,0,CSF3R;colony stimulating factor 3 receptor (granulocyte),GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0042475//odontogenesis of dentin-containing tooth;GO:0006952//defense response;GO:0030593//neutrophil chemotaxis;GO:0019221//cytokine-mediated signaling pathway;GO:0007165//signal transduction;GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0004896//cytokine receptor activity;GO:0004872//receptor activity,K05061//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway;Pathways in cancer
144100,140,0,0,0,12,9,42,82,58,0,15,347,"PLEKHA7;pleckstrin homology domain containing, family A member 7",GO:0070062//extracellular vesicular exosome;GO:0005915//zonula adherens;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0045218//zonula adherens maintenance;GO:0090136//epithelial cell-cell adhesion,GO:0070097//delta-catenin binding,K05632//Endocytosis;Ubiquitin mediated proteolysis;K05633//Endocytosis;Ubiquitin mediated proteolysis
144108,0,2,35,30,150,0,14,59,5,0,0,0,"SPTY2D1;SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)",-,-,-,-
144110,0,0,0,0,11,19,0,0,3,151,21,0,TMEM86A;transmembrane protein 86A,GO:0016021//integral component of membrane,-,-,-
144124,0,0,0,0,8,0,0,0,0,0,0,0,"OR10A5;olfactory receptor, family 10, subfamily A, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
144125,0,0,0,0,0,0,0,50,0,107,0,0,"OR2AG1;olfactory receptor, family 2, subfamily AG, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0005515//protein binding;GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
144132,49,11,38,51,24,21,20,0,104,0,47,0,DNHD1;dynein heavy chain domain 1,GO:0030286//dynein complex;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity,K10408//Huntington's disease
144165,0,0,0,0,0,16,23,71,37,175,0,36,PRICKLE1;prickle homolog 1 (Drosophila),GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005829//cytosol,"GO:0001843//neural tube closure;GO:2000691//negative regulation of cardiac muscle cell myoblast differentiation;GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006606//protein import into nucleus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0008270//zinc ion binding,K04511//Wnt signaling pathway
144193,0,0,0,0,0,0,39,45,0,0,0,0,AMDHD1;amidohydrolase domain containing 1,GO:0005829//cytosol,GO:0006548//histidine catabolic process;GO:0019556//histidine catabolic process to glutamate and formamide;GO:0034641//cellular nitrogen compound metabolic process;GO:0019557//histidine catabolic process to glutamate and formate;GO:0044281//small molecule metabolic process,GO:0050480//imidazolonepropionase activity;GO:0046872//metal ion binding,K01468//Nicotinate and nicotinamide metabolism;Metabolic pathways;Histidine metabolism
144195,1,0,0,0,0,0,18,0,35,187,0,0,"SLC2A14;solute carrier family 2 (facilitated glucose transporter), member 14",GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0055085//transmembrane transport;GO:0030154//cell differentiation;GO:0015758//glucose transport,GO:0005355//glucose transmembrane transporter activity,-
144233,0,0,0,13,18,12,0,64,0,0,17,0,BCDIN3D;BCDIN3 domain containing,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:2000632//negative regulation of pre-miRNA processing;GO:0010586//miRNA metabolic process;GO:0001510//RNA methylation,GO:0008171//O-methyltransferase activity;GO:0008173//RNA methyltransferase activity,K11447//Transcriptional misregulation in cancer;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
144245,0,0,0,1,0,26,29,0,70,414,0,0,"ALG10B;ALG10B, alpha-1,2-glucosyltransferase",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification,"GO:0016758//transferase activity, transferring hexosyl groups",K03850//Metabolic pathways;N-Glycan biosynthesis
144321,0,0,0,0,0,34,72,0,21,0,0,0,GLIPR1L2;GLI pathogenesis-related 1 like 2,GO:0016021//integral component of membrane,-,-,K04257//Olfactory transduction;K09299//Transcriptional misregulation in cancer;K00543//Tryptophan metabolism;Metabolic pathways
144348,0,77,1,120,514,0,22,0,10,0,0,0,ZNF664;zinc finger protein 664,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
144363,0,34,1,4,52,0,0,0,0,0,0,0,LYRM5;LYR motif containing 5,GO:0005739//mitochondrion,-,-,-
1444,0,0,0,0,0,0,0,1,8,0,4,0,CSHL1;chorionic somatomammotropin hormone-like 1,GO:0005576//extracellular region,-,GO:0005179//hormone activity;GO:0046872//metal ion binding,K05438//Neuroactive ligand-receptor interaction;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
144402,0,0,0,0,0,0,81,0,31,0,7,0,CPNE8;copine VIII,GO:0070062//extracellular vesicular exosome,-,-,K06491//Cell adhesion molecules (CAMs);Prion diseases;K15290//Synaptic vesicle cycle;K02677//B cell receptor signaling pathway;Salivary secretion;GABAergic synapse;Tight junction;Cholinergic synapse;Fc epsilon RI signaling pathway;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;Aldosterone-regulated sodium reabsorption;African trypanosomiasis;Pancreatic secretion;Long-term potentiation;Carbohydrate digestion and absorption;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Phototransduction - fly;Amoebiasis;Amphetamine addiction;Glutamatergic synapse;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;Vascular smooth muscle contraction;Calcium signaling pathway;Retrograde endocannabinoid signaling;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Long-term depression;Gastric acid secretion;Glioma;Pathogenic Escherichia coli infection;Focal adhesion;VEGF signaling pathway;Leishmaniasis;Serotonergic synapse;Influenza A;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Dopaminergic synapse;Gap junction;NF-kappa B signaling pathway;ErbB signaling pathway;MAPK signaling pathway;Morphine addiction
144404,120,39,0,4,17,14,47,0,53,1,0,56,TMEM120B;transmembrane protein 120B,GO:0016021//integral component of membrane,-,-,K14574//Ribosome biogenesis in eukaryotes
144406,0,0,0,0,0,12,40,0,22,0,0,225,WDR66;WD repeat domain 66,-,-,GO:0005509//calcium ion binding,-
144423,126,0,0,0,0,0,42,0,0,0,0,0,GLT1D1;glycosyltransferase 1 domain containing 1,GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0009058//biosynthetic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
144448,42,0,0,0,0,0,0,0,0,0,0,0,TSPAN19;tetraspanin 19,GO:0016021//integral component of membrane,-,-,K06509//p53 signaling pathway
144453,1,0,0,0,0,3,72,0,73,0,3,0,BEST3;bestrophin 3,GO:0005886//plasma membrane;GO:0034707//chloride channel complex,GO:0043271//negative regulation of ion transport;GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity,-
144455,10,0,0,0,0,19,0,0,104,0,8,0,E2F7;E2F transcription factor 7,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0001890//placenta development;GO:0032466//negative regulation of cytokinesis;GO:0060718//chorionic trophoblast cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0070365//hepatocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0032877//positive regulation of DNA endoreduplication;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002040//sprouting angiogenesis;GO:0060707//trophoblast giant cell differentiation",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042802//identical protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0005515//protein binding;GO:0001047//core promoter binding;GO:0003714//transcription corepressor activity,-
1445,0,2,0,13,19,0,0,58,109,0,7,0,CSK;c-src tyrosine kinase,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0005911//cell-cell junction;GO:0005737//cytoplasm,GO:0050852//T cell receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007596//blood coagulation;GO:0045779//negative regulation of bone resorption;GO:0046777//protein autophosphorylation;GO:0030168//platelet activation;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0033673//negative regulation of kinase activity;GO:0071375//cellular response to peptide hormone stimulus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032715//negative regulation of interleukin-6 production;GO:0048709//oligodendrocyte differentiation;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0007420//brain development;GO:0008285//negative regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050765//negative regulation of phagocytosis;GO:0034332//adherens junction organization;GO:0043406//positive regulation of MAP kinase activity;GO:0031295//T cell costimulation,GO:0004713//protein tyrosine kinase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0070064//proline-rich region binding;GO:0042802//identical protein binding,K05728//Epithelial cell signaling in Helicobacter pylori infection
144501,1,0,0,0,0,17,0,0,16,0,0,0,KRT80;keratin 80,GO:0030057//desmosome;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0005737//cytoplasm,-,GO:0005198//structural molecule activity,-
144568,92,0,17,14,12,17,43,105,85,2,6,0,A2ML1;alpha-2-macroglobulin-like 1,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0052548//regulation of endopeptidase activity;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030414//peptidase inhibitor activity,K03910//Complement and coagulation cascades
1446,0,0,0,0,0,0,0,0,9,0,0,0,CSN1S1;casein alpha s1,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0006810//transport,GO:0005215//transporter activity,-
144608,0,0,0,0,0,8,0,0,0,0,0,0,C12orf60;chromosome 12 open reading frame 60,-,-,-,-
144699,0,0,0,0,0,0,8,0,14,0,2,0,FBXL14;F-box and leucine-rich repeat protein 14,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
1447,0,0,0,0,0,0,18,23,18,0,0,0,CSN2;casein beta,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007595//lactation;GO:0043086//negative regulation of catalytic activity;GO:0006816//calcium ion transport,GO:0005509//calcium ion binding;GO:0005215//transporter activity;GO:0004857//enzyme inhibitor activity,-
144715,0,0,0,0,0,0,0,0,34,0,0,0,RAD9B;RAD9 homolog B (S. pombe),GO:0030896//checkpoint clamp complex;GO:0005654//nucleoplasm,GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0000077//DNA damage checkpoint,GO:0005515//protein binding,-
144717,0,0,0,11,13,26,0,0,47,0,16,0,"FAM109A;family with sequence similarity 109, member A",GO:0055037//recycling endosome;GO:0005802//trans-Golgi network;GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle,"GO:0007032//endosome organization;GO:0001881//receptor recycling;GO:0042147//retrograde transport, endosome to Golgi",GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K12326//MAPK signaling pathway;K01109//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism;K04349//Focal adhesion;MAPK signaling pathway
1448,0,0,0,0,0,14,0,0,0,0,0,0,CSN3;casein kappa,GO:0005615//extracellular space,GO:0007595//lactation;GO:0050821//protein stabilization,-,-
144809,8,0,0,0,0,0,0,59,0,0,0,0,"FAM216B;family with sequence similarity 216, member B",-,-,-,-
144811,62,18,0,5,2,0,0,24,51,0,1,0,LACC1;laccase (multicopper oxidoreductase) domain containing 1,-,-,-,-
144817,0,0,0,0,0,0,35,0,11,115,0,0,LINC00330;long intergenic non-protein coding RNA 330,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
144983,0,0,0,0,10,13,0,0,9,0,0,0,HNRNPA1L2;heterogeneous nuclear ribonucleoprotein A1-like 2,GO:0005681//spliceosomal complex;GO:0005737//cytoplasm,"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0051028//mRNA transport",GO:0003723//RNA binding;GO:0000166//nucleotide binding,K12741//Spliceosome
145165,35,0,0,0,28,5,18,0,0,0,0,0,ST13P4;suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 4,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,-,-,-
145173,200,0,0,10,0,51,0,76,41,1,0,0,"B3GALTL;beta 1,3-galactosyltransferase-like",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006004//fucose metabolic process;GO:0006486//protein glycosylation,"GO:0016757//transferase activity, transferring glycosyl groups",K13675//Other types of O-glycan biosynthesis
1452,185,55,0,60,196,3,0,0,12,0,17,1,"CSNK1A1;casein kinase 1, alpha 1",GO:0005813//centrosome;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0016607//nuclear speck;GO:0016020//membrane;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex,GO:0007166//cell surface receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007067//mitotic nuclear division;GO:0006468//protein phosphorylation;GO:0007165//signal transduction,GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K08957//Wnt signaling pathway;Hedgehog signaling pathway
145226,0,0,0,0,2,0,22,0,38,0,0,0,RDH12;retinol dehydrogenase 12 (all-trans/9-cis/11-cis),GO:0060342//photoreceptor inner segment membrane;GO:0005622//intracellular,"GO:0007601//visual perception;GO:0001523//retinoid metabolic process;GO:0055114//oxidation-reduction process;GO:0045494//photoreceptor cell maintenance;GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light",GO:0005515//protein binding;GO:0004745//retinol dehydrogenase activity,K11153//Metabolic pathways;Retinol metabolism
145241,0,0,0,0,0,0,0,0,12,0,0,0,ADAM21P1;ADAM metallopeptidase domain 21 pseudogene 1,-,-,-,-
145258,0,0,0,0,0,0,0,0,37,0,0,0,GSC;goosecoid homeobox,GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0030178//negative regulation of Wnt signaling pathway;GO:0014036//neural crest cell fate specification;GO:0007369//gastrulation;GO:0021904//dorsal/ventral neural tube patterning;GO:0048644//muscle organ morphogenesis;GO:0042474//middle ear morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0048704//embryonic skeletal system morphogenesis,GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding,-
145264,0,0,0,0,0,0,47,0,0,0,0,0,"SERPINA12;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12",GO:0005615//extracellular space,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03984//Complement and coagulation cascades
145270,106,0,0,0,0,30,0,0,46,0,0,0,PRIMA1;proline rich membrane anchor 1,GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0031226//intrinsic component of plasma membrane,GO:0042135//neurotransmitter catabolic process;GO:0051649//establishment of localization in cell,GO:0043495//protein anchor;GO:0019899//enzyme binding,-
145282,0,25,135,20,22,0,0,0,9,0,7,0,MIPOL1;mirror-image polydactyly 1,GO:0005634//nucleus,-,-,-
1453,0,18,0,0,31,0,0,0,24,0,10,0,"CSNK1D;casein kinase 1, delta",GO:0005819//spindle;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005876//spindle microtubule;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,GO:0006468//protein phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0001934//positive regulation of protein phosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0042752//regulation of circadian rhythm;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0006281//DNA repair;GO:0051225//spindle assembly,GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0004674//protein serine/threonine kinase activity;GO:0042277//peptide binding;GO:0004672//protein kinase activity;GO:0050321//tau-protein kinase activity;GO:0001948//glycoprotein binding;GO:0005524//ATP binding,K08959//Gap junction;Hedgehog signaling pathway;Circadian rhythm - mammal
145376,0,0,0,0,5,0,0,0,15,8,0,0,"PPP1R36;protein phosphatase 1, regulatory subunit 36",-,GO:0010923//negative regulation of phosphatase activity,GO:0019902//phosphatase binding;GO:0004864//protein phosphatase inhibitor activity,-
145389,0,0,0,0,0,0,0,0,33,0,0,52,"SLC38A6;solute carrier family 38, member 6",GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0006865//amino acid transport,-,-
1454,0,0,0,0,0,0,19,0,0,0,0,0,"CSNK1E;casein kinase 1, epsilon",-,-,-,K08960//Circadian rhythm - mammal;Wnt signaling pathway;Circadian rhythm - fly;Hedgehog signaling pathway
145407,169,0,0,0,0,0,0,1,13,0,0,0,C14orf37;chromosome 14 open reading frame 37,GO:0016021//integral component of membrane,-,-,K10955//Amoebiasis;Vibrio cholerae infection
145447,0,0,0,3,0,0,0,0,10,0,0,0,ABHD12B;abhydrolase domain containing 12B,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
145482,0,21,0,38,48,28,16,0,0,73,0,0,PTGR2;prostaglandin reductase 2,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006693//prostaglandin metabolic process;GO:0055114//oxidation-reduction process,GO:0008270//zinc ion binding;GO:0036132//13-prostaglandin reductase activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity,-
145483,0,73,0,9,65,19,57,61,61,0,96,0,"FAM161B;family with sequence similarity 161, member B",-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
145497,120,0,0,0,0,0,6,45,11,0,2,0,LRRC74;leucine rich repeat containing 74,-,-,-,K10165//Tuberculosis;NOD-like receptor signaling pathway;Shigellosis
1455,0,0,1,3,0,0,21,0,25,0,0,0,"CSNK1G2;casein kinase 1, gamma 2",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane,GO:0016055//Wnt signaling pathway;GO:0030148//sphingolipid biosynthetic process;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0006665//sphingolipid metabolic process,GO:0001948//glycoprotein binding;GO:0000287//magnesium ion binding;GO:0042277//peptide binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0004674//protein serine/threonine kinase activity,K08958//Hedgehog signaling pathway
145501,0,0,0,0,0,17,12,0,14,0,7,0,ISM2;isthmin 2,GO:0005576//extracellular region,-,-,-
145508,0,0,0,9,4,14,0,0,29,0,8,0,CEP128;centrosomal protein 128kDa,GO:0005814//centriole;GO:0005737//cytoplasm;GO:0000922//spindle pole;GO:0005815//microtubule organizing center,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
145567,0,34,2,0,50,12,1,0,59,3,11,480,TTC7B;tetratricopeptide repeat domain 7B,-,-,-,-
145581,0,0,0,0,0,0,0,0,20,0,0,0,LRFN5;leucine rich repeat and fibronectin type III domain containing 5,GO:0016021//integral component of membrane,-,-,K07523//Axon guidance
1456,95,0,0,26,11,1,0,7,13,0,10,327,"CSNK1G3;casein kinase 1, gamma 3",GO:0005737//cytoplasm,GO:0006464//cellular protein modification process;GO:0016055//Wnt signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity,K08958//Hedgehog signaling pathway
145645,0,0,0,0,0,26,0,0,14,0,0,0,C15orf43;chromosome 15 open reading frame 43,-,-,-,-
1457,197,15,1,25,256,0,0,0,51,0,0,0,"CSNK2A1;casein kinase 2, alpha 1 polypeptide",GO:0005886//plasma membrane;GO:0031519//PcG protein complex;GO:0005829//cytosol;GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0016580//Sin3 complex,"GO:0061077//chaperone-mediated protein folding;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0030177//positive regulation of Wnt signaling pathway;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0046777//protein autophosphorylation;GO:0016055//Wnt signaling pathway;GO:0048511//rhythmic process;GO:0007411//axon guidance;GO:0071174//mitotic spindle checkpoint;GO:0006351//transcription, DNA-templated;GO:0030307//positive regulation of cell growth;GO:0045732//positive regulation of protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008284//positive regulation of cell proliferation",GO:0008013//beta-catenin binding;GO:0047485//protein N-terminus binding;GO:0019888//protein phosphatase regulator activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0051879//Hsp90 protein binding;GO:0004674//protein serine/threonine kinase activity,K03097//Adherens junction;Measles;Epstein-Barr virus infection;Ribosome biogenesis in eukaryotes;Herpes simplex infection;Wnt signaling pathway;Circadian rhythm - plant;Tight junction;NF-kappa B signaling pathway
145741,0,0,0,0,0,35,0,0,5,0,0,0,C2CD4A;C2 calcium-dependent domain containing 4A,GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer
145773,164,28,0,6,34,0,16,54,27,0,9,0,"FAM81A;family with sequence similarity 81, member A",-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
145781,0,0,0,0,0,0,0,0,24,0,0,0,GCOM1;GRINL1A complex locus 1,-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K12478//Tuberculosis;Endocytosis;Phagosome
145783,0,0,0,4,12,0,0,0,0,0,0,0,LOC145783;uncharacterized LOC145783,-,-,-,-
145788,0,0,1,0,0,0,0,0,0,0,0,0,C15orf65;chromosome 15 open reading frame 65,-,-,-,-
145814,0,0,0,0,0,8,0,0,0,6,0,0,PGPEP1L;pyroglutamyl-peptidase I-like,-,GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity,-
145853,0,0,0,0,13,0,0,0,0,0,0,0,C15orf61;chromosome 15 open reading frame 61,GO:0005576//extracellular region,-,-,-
145864,0,0,0,0,0,0,0,0,34,0,0,0,HAPLN3;hyaluronan and proteoglycan link protein 3,GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion,GO:0005540//hyaluronic acid binding,-
145873,0,22,1,27,55,0,1,0,0,0,0,0,MESP2;mesoderm posterior basic helix-loop-helix transcription factor 2,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008078//mesodermal cell migration;GO:0032525//somite rostral/caudal axis specification;GO:0007219//Notch signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression",GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
1459,0,0,0,0,17,1,22,1,5,0,8,0,"CSNK2A2;casein kinase 2, alpha prime polypeptide",GO:0005634//nucleus;GO:0005829//cytosol;GO:0031519//PcG protein complex,"GO:0071174//mitotic spindle checkpoint;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007411//axon guidance;GO:0000278//mitotic cell cycle;GO:0016055//Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K03097//Wnt signaling pathway;Herpes simplex infection;Ribosome biogenesis in eukaryotes;Epstein-Barr virus infection;Measles;Adherens junction;NF-kappa B signaling pathway;Tight junction;Circadian rhythm - plant
145942,0,18,0,0,0,0,0,25,33,0,0,0,TMCO5A;transmembrane and coiled-coil domains 5A,GO:0016021//integral component of membrane,-,-,-
145946,0,0,0,0,0,0,0,0,13,0,0,0,SPATA8;spermatogenesis associated 8,-,-,-,-
145957,66,0,0,4,96,0,0,0,9,0,0,0,NRG4;neuregulin 4,GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0008083//growth factor activity,K05458//ErbB signaling pathway
146,0,0,0,0,0,0,18,66,0,0,0,0,ADRA1D;adrenoceptor alpha 1D,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0008283//cell proliferation;GO:0071875//adrenergic receptor signaling pathway;GO:0001994//norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0007275//multicellular organismal development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0006259//DNA metabolic process;GO:0001986//negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure,GO:0004937//alpha1-adrenergic receptor activity,K04137//Vascular smooth muscle contraction;Calcium signaling pathway;Salivary secretion;Neuroactive ligand-receptor interaction
146050,0,0,0,15,29,0,26,0,49,0,26,0,ZSCAN29;zinc finger and SCAN domain containing 29,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
146057,0,0,0,17,88,15,6,0,5,0,0,102,TTBK2;tau tubulin kinase 2,GO:0005634//nucleus;GO:0035869//ciliary transition zone;GO:0005829//cytosol;GO:0005814//centriole;GO:0005615//extracellular space;GO:0036064//ciliary basal body,GO:0008219//cell death;GO:0007224//smoothened signaling pathway;GO:0042384//cilium assembly;GO:0018105//peptidyl-serine phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
146059,17,0,0,5,41,9,25,0,69,53,17,0,CDAN1;codanin 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system,GO:0008104//protein localization;GO:0031497//chromatin assembly;GO:0008156//negative regulation of DNA replication;GO:0006325//chromatin organization,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
146167,0,0,0,0,0,0,0,111,13,3,5,0,"SLC38A8;solute carrier family 38, member 8",GO:0016021//integral component of membrane,GO:0006865//amino acid transport;GO:0006814//sodium ion transport,-,-
146177,150,0,0,0,5,0,32,0,44,0,22,0,VWA3A;von Willebrand factor A domain containing 3A,GO:0005576//extracellular region,-,-,-
146183,0,0,0,0,0,0,0,4,31,0,0,0,OTOA;otoancorin,GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix,GO:0007605//sensory perception of sound;GO:0007160//cell-matrix adhesion;GO:0019226//transmission of nerve impulse,-,-
146198,96,0,0,11,44,16,14,0,10,0,0,0,ZFP90;ZFP90 zinc finger protein,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043392//negative regulation of DNA binding",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1462,73,0,62,0,0,0,38,1,137,1,13,0,VCAN;versican,GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0016020//membrane;GO:0043202//lysosomal lumen;GO:0005578//proteinaceous extracellular matrix,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0008347//glial cell migration;GO:0007507//heart development;GO:0001649//osteoblast differentiation;GO:0030198//extracellular matrix organization;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0007275//multicellular organismal development;GO:0007155//cell adhesion;GO:0008037//cell recognition,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding;GO:0005539//glycosaminoglycan binding,K06793//Cell adhesion molecules (CAMs)
146206,49,0,0,12,10,40,37,0,21,0,37,0,"RLTPR;RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing",GO:0005911//cell-cell junction;GO:0001772//immunological synapse;GO:0008290//F-actin capping protein complex;GO:0005737//cytoplasm;GO:0016020//membrane,GO:1902715//positive regulation of interferon-gamma secretion;GO:0016477//cell migration;GO:0042102//positive regulation of T cell proliferation;GO:0048538//thymus development;GO:0032729//positive regulation of interferon-gamma production;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0045184//establishment of protein localization;GO:0048872//homeostasis of number of cells;GO:0030011//maintenance of cell polarity;GO:0050852//T cell receptor signaling pathway,-,K11147//Metabolic pathways;Peroxisome;Retinol metabolism;K12798//NOD-like receptor signaling pathway
146212,0,0,0,0,0,20,57,0,12,1,0,325,KCTD19;potassium channel tetramerization domain containing 19,-,GO:0051260//protein homooligomerization,-,-
146223,0,0,0,0,6,0,7,0,0,0,0,0,CMTM4;CKLF-like MARVEL transmembrane domain containing 4,GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
146225,0,0,0,0,0,0,0,23,0,0,0,0,CMTM2;CKLF-like MARVEL transmembrane domain containing 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
146227,0,0,0,0,0,0,0,83,6,0,0,0,"BEAN1;brain expressed, associated with NEDD4, 1",GO:0016021//integral component of membrane,GO:0008219//cell death,-,-
146279,0,0,0,0,0,3,0,0,23,0,2,0,TEKT5;tektin 5,GO:0005874//microtubule;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium,-,-,K04688//TGF-beta signaling pathway;ErbB signaling pathway;Fc gamma R-mediated phagocytosis;Insulin signaling pathway;Acute myeloid leukemia;mTOR signaling pathway
1463,59,0,0,0,0,1,35,0,109,0,7,0,NCAN;neurocan,GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0043202//lysosomal lumen,GO:0051823//regulation of synapse structural plasticity;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0007411//axon guidance;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process,GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding;GO:0005509//calcium ion binding,-
146310,0,0,0,0,0,0,9,0,0,0,0,0,RNF151;ring finger protein 151,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0016567//protein ubiquitination;GO:0007283//spermatogenesis,GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
146325,0,0,0,0,0,0,0,25,6,0,0,0,PRR35;proline rich 35,-,-,-,K12826//Spliceosome
146330,85,0,0,0,0,0,17,0,0,0,8,0,FBXL16;F-box and leucine-rich repeat protein 16,-,-,-,-
146378,0,15,0,0,0,12,0,0,0,0,0,0,C16orf92;chromosome 16 open reading frame 92,GO:0016021//integral component of membrane,-,-,-
146395,0,0,0,0,0,19,0,6,24,0,16,0,GSG1L;GSG1-like,GO:0032279//asymmetric synapse;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,-,-
1464,36,0,0,3,0,10,93,0,59,1,18,0,CSPG4;chondroitin sulfate proteoglycan 4,GO:0009986//cell surface;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen;GO:0016324//apical plasma membrane;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane,GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0008347//glial cell migration;GO:0001525//angiogenesis;GO:0048771//tissue remodeling;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction;GO:0000187//activation of MAPK activity;GO:0008283//cell proliferation,GO:0004871//signal transducer activity;GO:0019901//protein kinase binding,-
146429,0,0,0,0,0,0,24,1,20,0,0,0,"SLC22A31;solute carrier family 22, member 31",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006811//ion transport,GO:0022857//transmembrane transporter activity,-
146433,110,0,0,0,0,12,41,0,13,0,0,0,IL34;interleukin 34,GO:0005615//extracellular space,GO:0001934//positive regulation of protein phosphorylation;GO:0006954//inflammatory response;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation,GO:0008083//growth factor activity;GO:0005157//macrophage colony-stimulating factor receptor binding;GO:0005125//cytokine activity,-
146434,0,0,0,0,6,12,17,0,0,0,0,0,ZNF597;zinc finger protein 597,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
146439,0,0,0,1,0,0,0,19,7,0,0,0,CCDC64B;coiled-coil domain containing 64B,-,-,GO:0017137//Rab GTPase binding,-
146456,1,0,0,12,0,0,15,0,17,0,0,526,TMED6;transmembrane emp24 protein transport domain containing 6,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
146481,78,0,0,0,6,0,0,0,0,0,0,0,"LOC146481;FSHD region gene 2 family, member C pseudogene",-,-,-,-
1465,0,16,2,1,78,0,4,2,20,0,11,0,CSRP1;cysteine and glycine-rich protein 1,GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0005634//nucleus,GO:0070527//platelet aggregation,GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
146540,64,0,0,0,7,0,0,0,0,31,0,0,ZNF785;zinc finger protein 785,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
146542,0,0,0,0,0,0,0,1,13,0,0,1,ZNF688;zinc finger protein 688,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
146547,128,0,23,0,0,0,0,0,18,0,0,0,"PRSS36;protease, serine, 36",GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
146556,0,0,0,0,0,0,0,0,30,0,8,356,C16orf89;chromosome 16 open reading frame 89,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,-,GO:0042803//protein homodimerization activity,K11447//Transcriptional misregulation in cancer;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
146562,0,0,0,0,0,13,0,59,36,0,33,0,C16orf71;chromosome 16 open reading frame 71,-,-,-,-
146664,0,0,0,0,0,14,0,44,127,0,0,0,"MGAT5B;mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006487//protein N-linked glycosylation,"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity",K09661//Other types of O-glycan biosynthesis;N-Glycan biosynthesis;Metabolic pathways
146691,0,33,0,23,100,18,0,144,75,0,0,0,TOM1L2;target of myb1-like 2 (chicken),GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0006886//intracellular protein transport;GO:0045839//negative regulation of mitosis,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0030276//clathrin binding,K12182//Phagosome;Endocytosis;K04705//Endocytosis;Jak-STAT signaling pathway;K12404//Lysosome
146705,0,0,0,0,1,0,1,0,51,0,0,0,ENTHD2;ENTH domain containing 2,GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle,-,-,-
146712,106,0,0,0,0,0,0,1,0,0,0,235,"B3GNTL1;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1",-,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",K07204//mTOR signaling pathway;Insulin signaling pathway
146713,0,0,0,0,0,29,0,4,19,0,0,0,"RBFOX3;RNA binding protein, fox-1 homolog (C. elegans) 3",GO:0043204//perikaryon;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",GO:0003677//DNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
146722,27,0,0,0,0,18,0,0,0,0,9,0,CD300LF;CD300 molecule-like family member f,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0002376//immune system process,-,-
146723,0,0,0,0,0,11,0,0,26,0,5,0,C17orf77;chromosome 17 open reading frame 77,GO:0005576//extracellular region,-,-,K14443//RNA degradation;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
146754,114,0,0,2,0,15,93,141,130,9,16,0,"DNAH2;dynein, axonemal, heavy chain 2",GO:0005858//axonemal dynein complex;GO:0005874//microtubule,GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0007018//microtubule-based movement;GO:0001539//cilium or flagellum-dependent cell motility,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,K10408//Huntington's disease
146771,84,0,0,0,0,16,5,0,75,0,0,0,"TCAM1P;testicular cell adhesion molecule 1, pseudogene",-,-,-,K06490//African trypanosomiasis;Leukocyte transendothelial migration;Influenza A;Malaria;NF-kappa B signaling pathway;Rheumatoid arthritis;HTLV-I infection;Epstein-Barr virus infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Viral myocarditis;Staphylococcus aureus infection
146779,0,0,0,0,0,18,0,0,11,0,0,0,EFCAB3;EF-hand calcium binding domain 3,-,-,GO:0005509//calcium ion binding,K02183//Melanogenesis;Glioma;Gastric acid secretion;Neurotrophin signaling pathway;Alzheimer's disease;Salivary secretion;Calcium signaling pathway;Olfactory transduction;Plant-pathogen interaction;Phototransduction - fly;Vascular smooth muscle contraction;Oocyte meiosis;Amphetamine addiction;Long-term potentiation;Alcoholism;Pertussis;Tuberculosis;Insulin signaling pathway;Phototransduction;Phosphatidylinositol signaling system;GnRH signaling pathway;Dopaminergic synapse
1468,0,1,0,0,10,0,21,0,45,0,0,0,"SLC25A10;solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus,"GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0000098//sulfur amino acid catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006839//mitochondrial transport;GO:0006835//dicarboxylic acid transport;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006094//gluconeogenesis;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase",GO:0005515//protein binding;GO:0005310//dicarboxylic acid transmembrane transporter activity,K13577//Proximal tubule bicarbonate reclamation
146802,0,0,0,4,21,22,0,0,60,0,8,0,"SLC47A2;solute carrier family 47 (multidrug and toxin extrusion), member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0006855//drug transmembrane transport,GO:0015297//antiporter activity;GO:0015238//drug transmembrane transporter activity,-
146822,0,0,0,0,0,0,0,0,0,1,9,0,CDRT15;CMT1A duplicated region transcript 15,-,-,-,-
146845,0,0,0,0,0,12,0,0,56,0,0,0,WDR16;WD repeat domain 16,GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12602//RNA degradation
146849,0,0,0,0,0,0,16,0,0,0,0,0,CCDC42;coiled-coil domain containing 42,-,-,-,K08501//SNARE interactions in vesicular transport
146850,0,0,0,0,0,0,0,0,37,0,7,0,"PIK3R6;phosphoinositide-3-kinase, regulatory subunit 6","GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0005829//cytosol;GO:0016020//membrane",GO:0007186//G-protein coupled receptor signaling pathway;GO:0046854//phosphatidylinositol phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007596//blood coagulation;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0030168//platelet activation;GO:0001525//angiogenesis;GO:0044281//small molecule metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0006644//phospholipid metabolic process;GO:0045766//positive regulation of angiogenesis,"GO:0046935//1-phosphatidylinositol-3-kinase regulator activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0005515//protein binding",K02649//Endometrial cancer;Osteoclast differentiation;Toxoplasmosis;Focal adhesion;VEGF signaling pathway;Glioma;Bacterial invasion of epithelial cells;HTLV-I infection;Jak-STAT signaling pathway;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;mTOR signaling pathway;Apoptosis;Epstein-Barr virus infection;Renal cell carcinoma;ErbB signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Toll-like receptor signaling pathway;Influenza A;Neurotrophin signaling pathway;Melanoma;Hepatitis C;Regulation of actin cytoskeleton;Non-small cell lung cancer;Measles;Fc epsilon RI signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Type II diabetes mellitus;Colorectal cancer;Amoebiasis;Insulin signaling pathway;Phosphatidylinositol signaling system;Carbohydrate digestion and absorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;Aldosterone-regulated sodium reabsorption;Prostate cancer
146852,0,0,0,0,0,46,0,0,8,0,0,0,ODF4;outer dense fiber of sperm tails 4,GO:0001520//outer dense fiber;GO:0031514//motile cilium;GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
146857,0,0,0,4,13,0,74,3,41,2,0,8,SLFN13;schlafen family member 13,GO:0005622//intracellular,-,GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
146861,0,0,0,0,0,0,0,0,6,0,0,0,"SLC35G3;solute carrier family 35, member G3",GO:0016021//integral component of membrane,-,-,-
146862,0,0,0,0,7,26,22,87,42,0,9,0,UNC45B;unc-45 homolog B (C. elegans),GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0007517//muscle organ development;GO:0061077//chaperone-mediated protein folding;GO:0030154//cell differentiation,GO:0051879//Hsp90 protein binding,K04460//MAPK signaling pathway
146880,69,0,0,0,0,1,18,0,55,0,19,0,LOC146880;Rho GTPase activating protein 27 pseudogene,-,-,-,-
146894,0,0,0,0,0,37,0,64,10,0,0,0,CD300LG;CD300 molecule-like family member g,GO:0016324//apical plasma membrane;GO:0032585//multivesicular body membrane;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0002376//immune system process,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
1469,0,0,0,0,0,0,15,29,10,0,0,0,CST1;cystatin SN,GO:0005615//extracellular space,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0010951//negative regulation of endopeptidase activity,GO:0004869//cysteine-type endopeptidase inhibitor activity,K13898//Salivary secretion;K13900//Salivary secretion;K13897//Salivary secretion
146909,94,0,0,0,0,28,0,0,20,7,16,0,KIF18B;kinesin family member 18B,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005871//kinesin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000235//astral microtubule;GO:0035371//microtubule plus-end,GO:0000070//mitotic sister chromatid segregation;GO:0007019//microtubule depolymerization;GO:0007018//microtubule-based movement;GO:0051302//regulation of cell division;GO:0000278//mitotic cell cycle;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity,-
146923,15,0,0,1,45,24,31,21,19,0,1,0,RUNDC1;RUN domain containing 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
146956,0,106,38,118,205,0,0,0,24,0,69,0,EME1;essential meiotic structure-specific endonuclease 1,GO:0005730//nucleolus;GO:0005720//nuclear heterochromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006310//DNA recombination;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair,GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,K10882//Homologous recombination;Fanconi anemia pathway
147,0,0,0,0,0,0,0,0,14,0,0,0,ADRA1B;adrenoceptor alpha 1B,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005887//integral component of plasma membrane,GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0045819//positive regulation of glycogen catabolic process;GO:0007275//multicellular organismal development;GO:0019229//regulation of vasoconstriction;GO:0043278//response to morphine;GO:0001975//response to amphetamine;GO:0008542//visual learning;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0001987//vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure;GO:0007512//adult heart development;GO:0071875//adrenergic receptor signaling pathway;GO:0045818//negative regulation of glycogen catabolic process;GO:0008283//cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0035265//organ growth;GO:0043410//positive regulation of MAPK cascade;GO:0016049//cell growth;GO:0007267//cell-cell signaling;GO:0007626//locomotory behavior;GO:0042593//glucose homeostasis;GO:0001974//blood vessel remodeling;GO:0048148//behavioral response to cocaine;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0055117//regulation of cardiac muscle contraction,GO:0004937//alpha1-adrenergic receptor activity;GO:0046982//protein heterodimerization activity,K04136//Vascular smooth muscle contraction;Neuroactive ligand-receptor interaction;Salivary secretion;Calcium signaling pathway
1470,0,0,0,0,0,0,3,0,10,0,0,0,CST2;cystatin SA,GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0004869//cysteine-type endopeptidase inhibitor activity,K13898//Salivary secretion;K13900//Salivary secretion;K13897//Salivary secretion
147007,0,0,1,0,4,0,23,0,14,0,11,0,TMEM199;transmembrane protein 199,GO:0016021//integral component of membrane,-,-,-
147011,1,0,0,0,0,4,0,1,5,0,0,331,PROCA1;protein interacting with cyclin A1,-,GO:0016042//lipid catabolic process,GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity,K01047//VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Long-term depression;Metabolic pathways;Vascular smooth muscle contraction;Linoleic acid metabolism;MAPK signaling pathway;Glutamatergic synapse;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;GnRH signaling pathway
147015,0,0,0,0,36,26,3,0,30,0,0,0,DHRS13;dehydrogenase/reductase (SDR family) member 13,GO:0005576//extracellular region;GO:0016020//membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
147040,0,1,44,0,0,0,0,0,27,0,1,0,KCTD11;potassium channel tetramerization domain containing 11,GO:0005737//cytoplasm,GO:0051260//protein homooligomerization;GO:0040008//regulation of growth;GO:0007406//negative regulation of neuroblast proliferation;GO:0045666//positive regulation of neuron differentiation;GO:0016567//protein ubiquitination;GO:0007049//cell cycle;GO:0045879//negative regulation of smoothened signaling pathway,-,-
147081,0,0,0,0,0,0,0,0,11,0,0,0,CRHR1-IT1;CRHR1 intronic transcript 1 (non-protein coding),GO:0005576//extracellular region,-,-,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
1471,0,0,9,6,2,37,0,0,7,0,0,0,CST3;cystatin C,GO:0005764//lysosome;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0043292//contractile fiber;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0005771//multivesicular body;GO:0031965//nuclear membrane;GO:0043025//neuronal cell body;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0001775//cell activation;GO:0010466//negative regulation of peptidase activity;GO:0070301//cellular response to hydrogen peroxide;GO:0001654//eye development;GO:0010711//negative regulation of collagen catabolic process;GO:0007420//brain development;GO:0007566//embryo implantation;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0042493//response to drug;GO:0006952//defense response;GO:0060009//Sertoli cell development;GO:0045861//negative regulation of proteolysis;GO:0043206//extracellular fibril organization;GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0009636//response to toxic substance;GO:0010951//negative regulation of endopeptidase activity;GO:0045740//positive regulation of DNA replication;GO:0031667//response to nutrient levels;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0048678//response to axon injury;GO:0060548//negative regulation of cell death;GO:0009743//response to carbohydrate;GO:0007431//salivary gland development;GO:0060313//negative regulation of blood vessel remodeling;GO:0034103//regulation of tissue remodeling;GO:0060311//negative regulation of elastin catabolic process;GO:0032355//response to estradiol",GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0002020//protease binding;GO:0001540//beta-amyloid binding;GO:0004866//endopeptidase inhibitor activity,K13899//Salivary secretion
147111,0,0,0,0,0,0,12,0,14,0,0,0,NOTUM;notum pectinacetylesterase homolog (Drosophila),GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
147138,0,23,0,5,0,1,19,0,5,0,12,0,TMC8;transmembrane channel-like 8,GO:0005789//endoplasmic reticulum membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0055069//zinc ion homeostasis;GO:0006811//ion transport;GO:0001558//regulation of cell growth;GO:0032091//negative regulation of protein binding;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0032460//negative regulation of protein oligomerization,GO:0005102//receptor binding;GO:0005515//protein binding,-
147166,0,0,0,0,0,0,0,36,0,0,9,0,TRIM16L;tripartite motif containing 16-like,GO:0005737//cytoplasm,-,-,-
147172,0,36,0,0,16,0,33,0,34,8,3,284,LRRC37BP1;leucine rich repeat containing 37B pseudogene 1,-,-,-,K04678//Ubiquitin mediated proteolysis;TGF-beta signaling pathway;Endocytosis
147179,0,0,0,12,48,16,23,0,15,0,1,138,"WIPF2;WAS/WASL interacting protein family, member 2",GO:0005856//cytoskeleton;GO:0005829//cytosol,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045087//innate immune response,GO:0005515//protein binding;GO:0003779//actin binding,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
147183,0,0,0,0,0,0,12,0,35,0,9,0,KRT25;keratin 25,GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0042633//hair cycle;GO:0045109//intermediate filament organization;GO:0031069//hair follicle morphogenesis;GO:0007568//aging,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
147184,0,35,0,0,11,0,0,0,61,0,0,0,TMEM99;transmembrane protein 99,GO:0016021//integral component of membrane,-,-,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
1472,0,0,0,0,0,0,0,2,20,0,0,0,CST4;cystatin S,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0045861//negative regulation of proteolysis;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0010951//negative regulation of endopeptidase activity;GO:0001895//retina homeostasis,GO:0004869//cysteine-type endopeptidase inhibitor activity,K13898//Salivary secretion;K13897//Salivary secretion;K13900//Salivary secretion
1473,0,0,0,0,0,0,0,0,15,0,0,0,CST5;cystatin D,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity,K13900//Salivary secretion;K13901//Salivary secretion;K13898//Salivary secretion
147323,0,0,0,0,0,0,0,0,5,0,0,0,STARD6;StAR-related lipid transfer (START) domain containing 6,-,GO:0006869//lipid transport,GO:0008289//lipid binding,-
147339,0,0,37,9,44,0,3,1,22,0,12,0,C18orf25;chromosome 18 open reading frame 25,-,-,-,-
147372,0,0,0,0,0,5,27,0,66,0,8,0,CCBE1;collagen and calcium binding EGF domains 1,GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0031012//extracellular matrix,GO:1901492//positive regulation of lymphangiogenesis;GO:0002040//sprouting angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0001946//lymphangiogenesis;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:0010954//positive regulation of protein processing;GO:0048845//venous blood vessel morphogenesis;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0010595//positive regulation of endothelial cell migration,GO:0005509//calcium ion binding;GO:0002020//protease binding;GO:0005518//collagen binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
147381,0,0,0,0,0,24,11,0,0,0,0,0,CBLN2;cerebellin 2 precursor,GO:0005615//extracellular space,GO:0051965//positive regulation of synapse assembly,-,K03986//Pertussis;Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection;K03988//Prion diseases;Systemic lupus erythematosus;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades;K03987//Pertussis;Complement and coagulation cascades;Chagas disease (American trypanosomiasis);Systemic lupus erythematosus;Prion diseases;Staphylococcus aureus infection
1474,0,0,0,0,0,0,0,0,0,57,0,1,CST6;cystatin E/M,GO:0070062//extracellular vesicular exosome;GO:0001533//cornified envelope,GO:0010951//negative regulation of endopeptidase activity;GO:0009653//anatomical structure morphogenesis;GO:0008544//epidermis development,GO:0004869//cysteine-type endopeptidase inhibitor activity,-
147407,0,0,0,0,0,0,17,0,0,0,0,0,"SLC25A52;solute carrier family 25, member 52",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
147409,1,0,0,0,0,0,32,8,29,37,23,451,DSG4;desmoglein 4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030057//desmosome,GO:0042640//anagen;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016337//single organismal cell-cell adhesion;GO:0030509//BMP signaling pathway;GO:0030216//keratinocyte differentiation,GO:0005509//calcium ion binding,-
147463,0,0,0,0,0,0,0,0,5,1,5,0,ANKRD29;ankyrin repeat domain 29,-,-,-,-
147495,0,44,30,0,22,0,16,0,27,0,14,0,APCDD1;adenomatosis polyposis coli down-regulated 1,GO:0005887//integral component of plasma membrane,GO:0043615//astrocyte cell migration;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0001942//hair follicle development,GO:0017147//Wnt-protein binding,-
1475,0,0,0,7,15,0,0,0,0,0,0,0,CSTA;cystatin A (stefin A),GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0001533//cornified envelope;GO:0005634//nucleus,GO:0016337//single organismal cell-cell adhesion;GO:0018149//peptide cross-linking;GO:0010466//negative regulation of peptidase activity;GO:0045861//negative regulation of proteolysis;GO:0030216//keratinocyte differentiation;GO:0010951//negative regulation of endopeptidase activity,"GO:0002020//protease binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity",-
1476,0,16,0,13,3,8,0,1,0,0,0,0,CSTB;cystatin B (stefin B),GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0045861//negative regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0008344//adult locomotory behavior;GO:0042981//regulation of apoptotic process;GO:0010466//negative regulation of peptidase activity,GO:0002020//protease binding;GO:0004866//endopeptidase inhibitor activity;GO:0044822//poly(A) RNA binding;GO:0004869//cysteine-type endopeptidase inhibitor activity,-
147645,0,0,0,6,2,0,24,0,32,0,0,0,VSIG10L;V-set and immunoglobulin domain containing 10 like,GO:0016021//integral component of membrane,-,-,-
147646,0,0,0,0,0,14,15,0,0,0,12,0,C19orf84;chromosome 19 open reading frame 84,-,-,-,-
147657,87,0,0,0,34,1,63,0,47,0,0,0,ZNF480;zinc finger protein 480,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
147658,0,0,0,0,0,0,18,0,42,0,0,0,ZNF534;zinc finger protein 534,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K01520//Metabolic pathways;Pyrimidine metabolism
147660,0,0,0,0,0,11,18,0,23,200,0,0,ZNF578;zinc finger protein 578,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
147664,0,0,0,0,0,21,13,0,0,0,10,0,"ERVV-1;endogenous retrovirus group V, member 1",GO:0016021//integral component of membrane,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
147670,1,0,0,0,0,0,0,0,10,0,0,0,SMIM17;small integral membrane protein 17,GO:0016021//integral component of membrane,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K14443//RNA degradation
147685,0,0,0,0,0,0,0,61,0,0,14,0,C19orf18;chromosome 19 open reading frame 18,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
147686,9,0,0,0,1,22,0,0,0,109,0,0,ZNF418;zinc finger protein 418,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
147687,0,0,0,0,0,0,0,0,1,0,0,0,ZNF417;zinc finger protein 417,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147694,0,0,0,11,26,25,0,0,10,0,0,0,ZNF548;zinc finger protein 548,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
147699,0,0,0,0,0,3,27,0,48,0,0,0,"PPM1N;protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)",-,GO:0016311//dephosphorylation,GO:0030145//manganese ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0000287//magnesium ion binding,K04461//MAPK signaling pathway
1477,0,28,0,5,42,0,0,0,9,162,0,0,"CSTF1;cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa",GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006378//mRNA polyadenylation;GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006379//mRNA cleavage;GO:0031124//mRNA 3'-end processing;GO:0006396//RNA processing",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K14406//mRNA surveillance pathway
147700,174,0,0,68,218,37,0,79,39,77,236,0,KLC3;kinesin light chain 3,GO:0035253//ciliary rootlet;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex;GO:0043005//neuron projection;GO:0031514//motile cilium,GO:0008088//axon cargo transport;GO:0008152//metabolic process,GO:0019894//kinesin binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding,K10407//Salmonella infection
147710,0,0,0,0,0,0,0,0,0,0,11,0,"IGSF23;immunoglobulin superfamily, member 23",GO:0016021//integral component of membrane,-,-,-
147719,82,34,0,0,7,7,0,0,34,1,11,0,LYPD4;LY6/PLAUR domain containing 4,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,-,-,-
147741,109,0,0,0,0,0,0,2,43,0,0,608,ZNF560;zinc finger protein 560,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147744,0,0,0,0,0,0,0,0,12,206,7,0,TMEM190;transmembrane protein 190,GO:0002079//inner acrosomal membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0002244//hematopoietic progenitor cell differentiation,GO:0043621//protein self-association,-
147746,0,0,0,0,0,11,0,0,24,0,0,0,HIPK4;homeodomain interacting protein kinase 4,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:1901796//regulation of signal transduction by p53 class mediator;GO:0018105//peptidyl-serine phosphorylation;GO:0016572//histone phosphorylation;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
147798,0,0,0,12,20,25,0,0,6,0,13,0,TMC4;transmembrane channel-like 4,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
1478,0,22,0,0,0,0,1,0,14,0,0,4,"CSTF2;cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071920//cleavage body;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005730//nucleolus,"GO:0031124//mRNA 3'-end processing;GO:0006379//mRNA cleavage;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003723//RNA binding,K14407//mRNA surveillance pathway
147804,0,40,2,55,348,10,0,0,6,0,0,0,TPM3P9;tropomyosin 3 pseudogene 9,-,-,-,K09290//Dilated cardiomyopathy;Thyroid cancer;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Pathways in cancer
147808,0,0,0,7,1,0,0,0,6,3,15,1,ZNF784;zinc finger protein 784,GO:0005634//nucleus,"GO:0002244//hematopoietic progenitor cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147837,0,0,0,24,16,0,23,1,10,0,0,0,ZNF563;zinc finger protein 563,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
147872,0,0,0,0,0,17,51,0,13,0,0,0,CCDC155;coiled-coil domain containing 155,"GO:0000781//chromosome, telomeric region;GO:0005640//nuclear outer membrane;GO:0016021//integral component of membrane",-,GO:0005509//calcium ion binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K06674//Cell cycle - yeast
1479,0,0,0,9,39,32,0,0,39,0,0,0,"CSTF3;cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0031124//mRNA 3'-end processing;GO:0006379//mRNA cleavage",GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K14408//mRNA surveillance pathway
147912,0,49,50,15,12,0,0,104,7,0,19,0,SIX5;SIX homeobox 5,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007286//spermatid development;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0002088//lens development in camera-type eye;GO:0008285//negative regulation of cell proliferation",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,K15615//Transcriptional misregulation in cancer
147920,0,6,0,0,0,0,0,0,0,0,0,0,IGFL2;IGF-like family member 2,GO:0005576//extracellular region,-,-,-
147923,0,0,0,9,4,12,46,0,15,0,20,310,ZNF420;zinc finger protein 420,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
147929,0,0,2,17,42,0,0,0,0,0,0,0,ZNF565;zinc finger protein 565,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147945,0,0,0,0,0,0,0,0,2,193,0,0,"NLRP4;NLR family, pyrin domain containing 4",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0006954//inflammatory response,GO:0005524//ATP binding,K12800//Influenza A;NOD-like receptor signaling pathway;Pertussis
147947,3,0,0,46,26,0,4,0,0,0,26,0,"ZNF542P;zinc finger protein 542, pseudogene",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147948,0,0,1,15,0,0,0,0,9,0,0,0,ZNF582;zinc finger protein 582,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147949,0,0,0,0,0,9,0,0,8,0,7,0,ZNF583;zinc finger protein 583,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
147965,72,0,0,0,0,0,0,0,9,1,0,0,"FAM98C;family with sequence similarity 98, member C",-,-,-,-
147968,200,295,27,265,1082,8,17,78,28,0,120,0,CAPN12;calpain 12,GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
147991,0,0,0,5,0,0,20,103,76,0,11,0,DPY19L3;dpy-19-like 3 (C. elegans),GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
148,0,0,0,0,1,0,16,0,21,0,0,0,ADRA1A;adrenoceptor alpha 1A,GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0030018//Z disc;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus,"GO:0006939//smooth muscle contraction;GO:0007568//aging;GO:0060402//calcium ion transport into cytosol;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0001994//norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0045760//positive regulation of action potential;GO:0045907//positive regulation of vasoconstriction;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0060452//positive regulation of cardiac muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043410//positive regulation of MAPK cascade;GO:0016049//cell growth;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0008285//negative regulation of cell proliferation;GO:0035265//organ growth;GO:0035556//intracellular signal transduction;GO:0060073//micturition;GO:0009725//response to hormone;GO:0007165//signal transduction;GO:0007512//adult heart development;GO:0090037//positive regulation of protein kinase C signaling;GO:0001997//positive regulation of the force of heart contraction by epinephrine-norepinephrine;GO:0001985//negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006915//apoptotic process;GO:0097195//pilomotor reflex;GO:0007267//cell-cell signaling;GO:0045987//positive regulation of smooth muscle contraction;GO:0042493//response to drug;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0035024//negative regulation of Rho protein signal transduction;GO:0071875//adrenergic receptor signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway",GO:0046982//protein heterodimerization activity;GO:0004937//alpha1-adrenergic receptor activity,K04135//Vascular smooth muscle contraction;Calcium signaling pathway;Salivary secretion;Neuroactive ligand-receptor interaction
148022,0,0,0,7,6,0,0,65,7,25,0,0,TICAM1;toll-like receptor adaptor molecule 1,GO:0097342//ripoptosome;GO:0010008//endosome membrane;GO:0005829//cytosol,GO:0032760//positive regulation of tumor necrosis factor production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002281//macrophage activation involved in immune response;GO:0043330//response to exogenous dsRNA;GO:0032092//positive regulation of protein binding;GO:0002224//toll-like receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0006954//inflammatory response;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0051607//defense response to virus;GO:0032755//positive regulation of interleukin-6 production;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0043496//regulation of protein homodimerization activity;GO:0097190//apoptotic signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032816//positive regulation of natural killer cell activation,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004871//signal transducer activity,K05842//Pertussis;Influenza A;Toll-like receptor signaling pathway;Herpes simplex infection;Chagas disease (American trypanosomiasis);Hepatitis C;NF-kappa B signaling pathway
148066,0,0,0,0,0,2,23,0,2,0,0,0,ZNRF4;zinc and ring finger 4,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding,-
148103,0,0,0,0,0,0,0,1,26,0,7,0,ZNF599;zinc finger protein 599,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
148109,0,0,0,0,0,0,0,66,28,0,0,0,"FAM187B;family with sequence similarity 187, member B",GO:0016021//integral component of membrane,-,-,-
148113,1,0,34,0,6,33,15,134,15,0,0,0,CILP2;cartilage intermediate layer protein 2,GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome,-,GO:0004551//nucleotide diphosphatase activity;GO:0004035//alkaline phosphatase activity,K03544//Cell cycle - Caulobacter;K13908//Salivary secretion;K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
148137,0,0,0,0,0,0,12,0,6,0,10,0,PROSER3;proline and serine rich 3,-,-,-,-
148156,0,0,0,8,0,0,0,0,21,0,13,0,ZNF558;zinc finger protein 558,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
148170,0,0,1,8,81,0,0,1,0,0,10,0,CDC42EP5;CDC42 effector protein (Rho GTPase binding) 5,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016020//membrane,GO:0007254//JNK cascade;GO:0008360//regulation of cell shape;GO:0031274//positive regulation of pseudopodium assembly;GO:0007266//Rho protein signal transduction;GO:0030838//positive regulation of actin filament polymerization,GO:0017049//GTP-Rho binding,-
148198,0,0,0,0,0,0,32,0,44,0,0,0,ZNF98;zinc finger protein 98,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1482,0,0,0,0,0,0,20,40,18,0,0,0,NKX2-5;NK2 homeobox 5,GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045666//positive regulation of neuron differentiation;GO:0003007//heart morphogenesis;GO:0060928//atrioventricular node cell development;GO:0035050//embryonic heart tube development;GO:0060412//ventricular septum morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0045823//positive regulation of heart contraction;GO:0003350//pulmonary myocardium development;GO:0051891//positive regulation of cardioblast differentiation;GO:0003166//bundle of His development;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0030097//hemopoiesis;GO:0060043//regulation of cardiac muscle cell proliferation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0055117//regulation of cardiac muscle contraction;GO:0048536//spleen development;GO:0010765//positive regulation of sodium ion transport;GO:0060048//cardiac muscle contraction;GO:0010832//negative regulation of myotube differentiation;GO:0008284//positive regulation of cell proliferation;GO:0030509//BMP signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010735//positive regulation of transcription via serum response element binding;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:0007512//adult heart development;GO:0055015//ventricular cardiac muscle cell development;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003161//cardiac conduction system development;GO:0030878//thyroid gland development;GO:0003211//cardiac ventricle formation;GO:0030154//cell differentiation;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045214//sarcomere organization;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0001570//vasculogenesis;GO:0060413//atrial septum morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060971//embryonic heart tube left/right pattern formation;GO:0003285//septum secundum development;GO:0055005//ventricular cardiac myofibril assembly;GO:0060037//pharyngeal system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0055014//atrial cardiac muscle cell development;GO:0060070//canonical Wnt signaling pathway;GO:0060347//heart trabecula formation;GO:0001947//heart looping",GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0008134//transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0010736//serum response element binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
148203,101,0,0,9,30,15,20,0,21,0,6,0,ZNF738;zinc finger protein 738,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity,-
148206,0,0,0,0,9,0,18,0,58,0,1,0,ZNF714;zinc finger protein 714,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
148213,0,0,0,0,0,0,0,0,15,0,0,0,ZNF681;zinc finger protein 681,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
148223,0,2,0,0,2,8,15,1,0,4,1,0,C19orf25;chromosome 19 open reading frame 25,-,-,GO:0005515//protein binding,-
148229,68,0,0,0,0,45,0,10,24,0,18,1,"ATP8B3;ATPase, aminophospholipid transporter, class I, type 8B, member 3",GO:0002080//acrosomal membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0045332//phospholipid translocation;GO:0007339//binding of sperm to zona pellucida;GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity,K01530//Purine metabolism
148231,0,0,0,0,0,0,0,0,1,0,0,0,LINC00905;long intergenic non-protein coding RNA 905,-,-,-,-
148252,0,19,0,0,8,0,0,0,36,156,15,0,"DIRAS1;DIRAS family, GTP-binding RAS-like 1",GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0043406//positive regulation of MAP kinase activity,GO:0003924//GTPase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0005525//GTP binding,-
148254,0,1,93,0,11,53,74,0,66,0,0,0,ZNF555;zinc finger protein 555,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
148266,0,0,0,8,9,0,0,0,21,0,0,0,ZNF569;zinc finger protein 569,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
148281,0,0,0,0,0,21,1,0,22,0,9,0,SYT6;synaptotagmin VI,GO:0097038//perinuclear endoplasmic reticulum;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0030672//synaptic vesicle membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0060478//acrosomal vesicle exocytosis,GO:0005544//calcium-dependent phospholipid binding;GO:0005215//transporter activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0048306//calcium-dependent protein binding;GO:0030276//clathrin binding;GO:0019905//syntaxin binding,K15290//Synaptic vesicle cycle
148304,0,0,0,0,9,10,0,0,17,122,12,0,C1orf74;chromosome 1 open reading frame 74,-,-,-,-
148327,0,1,33,8,38,23,0,51,18,0,0,0,CREB3L4;cAMP responsive element binding protein 3-like 4,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,"GO:0007283//spermatogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein;GO:0006351//transcription, DNA-templated",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,K09048//Melanogenesis;Amphetamine addiction;Vasopressin-regulated water reabsorption;Prostate cancer;Alcoholism;Cocaine addiction;Dopaminergic synapse;Cholinergic synapse;Huntington's disease
148345,0,0,0,0,0,0,44,0,27,0,6,320,C1orf127;chromosome 1 open reading frame 127,-,-,-,-
148362,0,18,0,0,47,0,0,0,83,0,0,0,BROX;BRO1 domain and CAAX motif containing,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
148398,0,304,69,118,211,9,25,142,58,0,373,0,SAMD11;sterile alpha motif domain containing 11,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0042731//PH domain binding;GO:0032093//SAM domain binding;GO:0043621//protein self-association,-
148418,0,9,0,1,0,21,0,0,10,0,12,0,SAMD13;sterile alpha motif domain containing 13,-,-,-,-
148423,0,0,0,0,13,0,18,3,28,0,0,0,C1orf52;chromosome 1 open reading frame 52,-,-,GO:0044822//poly(A) RNA binding,K12756//Regulation of actin cytoskeleton;Tight junction;Leukocyte transendothelial migration;Focal adhesion
148479,0,1,0,0,0,15,15,6,59,0,0,0,PHF13;PHD finger protein 13,GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0007076//mitotic chromosome condensation;GO:0016568//chromatin modification;GO:0007059//chromosome segregation;GO:0000278//mitotic cell cycle,GO:0003682//chromatin binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding,-
148523,0,0,0,0,0,0,0,0,1,0,0,0,CIART;circadian associated repressor of transcription,GO:0005634//nucleus;GO:0016605//PML body,"GO:0045475//locomotor rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression",GO:0070888//E-box binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0005515//protein binding,-
148534,0,0,0,0,2,0,19,65,22,0,22,0,TMEM56;transmembrane protein 56,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
148545,0,0,0,0,0,28,1,0,2,0,0,0,"NBPF4;neuroblastoma breakpoint family, member 4",GO:0005737//cytoplasm,-,-,-
148581,0,0,0,0,0,0,13,0,0,0,0,0,UBE2U;ubiquitin-conjugating enzyme E2U (putative),-,GO:0016567//protein ubiquitination,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K10584//Ubiquitin mediated proteolysis
1486,0,35,0,32,41,7,0,0,49,0,0,0,"CTBS;chitobiase, di-N-acetyl-",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,GO:0006032//chitin catabolic process;GO:0009313//oligosaccharide catabolic process,GO:0004568//chitinase activity,-
148641,0,0,0,0,0,0,0,0,3,0,7,0,"SLC35F3;solute carrier family 35, member F3",GO:0016021//integral component of membrane,-,-,-
1487,0,0,1,37,60,11,0,22,9,1,4,0,CTBP1;C-terminal binding protein 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus,"GO:0050872//white fat cell differentiation;GO:0031065//positive regulation of histone deacetylation;GO:0006351//transcription, DNA-templated;GO:0019079//viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034401//regulation of transcription by chromatin organization;GO:0055114//oxidation-reduction process;GO:0007030//Golgi organization;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035067//negative regulation of histone acetylation;GO:0090241//negative regulation of histone H4 acetylation;GO:0051726//regulation of cell cycle","GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0070491//repressing transcription factor binding;GO:0051287//NAD binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0008134//transcription factor binding;GO:0008022//protein C-terminus binding",K04496//Notch signaling pathway;Wnt signaling pathway;Chronic myeloid leukemia;Pathways in cancer
148709,0,0,0,1,0,17,37,50,0,100,3,0,LOC148709;actin pseudogene,-,-,-,K05692//Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Gastric acid secretion;Pathogenic Escherichia coli infection;Vibrio cholerae infection;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection;Adherens junction;Phototransduction - fly;Viral myocarditis
148713,72,0,0,0,0,35,71,0,24,0,0,1,"PTPRVP;protein tyrosine phosphatase, receptor type, V, pseudogene",-,-,-,-
148738,0,0,0,0,0,0,0,0,6,2,0,0,HFE2;hemochromatosis type 2 (juvenile),GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0055072//iron ion homeostasis;GO:0030509//BMP signaling pathway,GO:0015026//coreceptor activity;GO:0005515//protein binding,-
148741,97,0,0,0,10,38,2,67,18,0,0,0,ANKRD35;ankyrin repeat domain 35,-,-,-,-
148753,0,0,0,4,2,0,10,1,12,0,15,663,"FAM163A;family with sequence similarity 163, member A",GO:0016021//integral component of membrane,-,-,-
148789,0,119,3,167,378,0,49,0,31,0,19,0,"B3GALNT2;beta-1,3-N-acetylgalactosaminyltransferase 2",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006493//protein O-linked glycosylation;GO:0006486//protein glycosylation,GO:0008375//acetylglucosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0008378//galactosyltransferase activity,-
1488,0,10,1,33,57,2,0,1,29,0,33,0,CTBP2;C-terminal binding protein 2,GO:0045202//synapse;GO:0030054//cell junction;GO:0017053//transcriptional repressor complex;GO:0005634//nucleus,"GO:0008285//negative regulation of cell proliferation;GO:0050872//white fat cell differentiation;GO:0055114//oxidation-reduction process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0019079//viral genome replication","GO:0003714//transcription corepressor activity;GO:0051287//NAD binding;GO:0005515//protein binding;GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",K04496//Notch signaling pathway;Pathways in cancer;Wnt signaling pathway;Chronic myeloid leukemia
148808,158,95,35,127,86,0,0,0,39,0,75,0,MFSD4;major facilitator superfamily domain containing 4,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,"K00232//PPAR signaling pathway;alpha-Linolenic acid metabolism;Peroxisome;Propanoate metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Biosynthesis of unsaturated fatty acids;Fatty acid metabolism"
148811,0,0,0,0,0,0,0,71,16,108,0,1,PM20D1;peptidase M20 domain containing 1,GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0050792//regulation of viral process;GO:0050691//regulation of defense response to virus by host;GO:1901215//negative regulation of neuron death,GO:0046872//metal ion binding;GO:0008233//peptidase activity,-
148823,185,0,0,0,1,0,15,0,22,0,0,0,"GCSAML;germinal center-associated, signaling and motility-like",-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
148867,0,0,0,9,6,27,3,0,86,62,0,0,"SLC30A7;solute carrier family 30 (zinc transporter), member 7",GO:0048471//perinuclear region of cytoplasm;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0006829//zinc ion transport;GO:0055085//transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0032119//sequestering of zinc ion,GO:0008324//cation transmembrane transporter activity,-
148870,1,0,0,0,0,0,33,0,60,0,11,0,CCDC27;coiled-coil domain containing 27,-,-,-,-
148898,0,104,47,18,18,0,0,130,1,0,37,0,C1orf213;chromosome 1 open reading frame 213,-,-,-,-
1489,36,0,0,0,0,0,0,0,0,0,0,0,CTF1;cardiotrophin 1,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0007517//muscle organ development;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0007399//nervous system development;GO:0048666//neuron development;GO:0008283//cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling,GO:0005146//leukemia inhibitory factor receptor binding;GO:0005125//cytokine activity,K05422//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
148930,21,0,0,0,0,0,0,0,0,0,0,0,KNCN;kinocilin,GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0060091//kinocilium;GO:0016021//integral component of membrane;GO:0036064//ciliary basal body;GO:0032437//cuticular plate,-,-,-
148932,0,18,0,0,10,0,0,0,5,0,0,0,MOB3C;MOB kinase activator 3C,-,-,GO:0046872//metal ion binding,K06685//Cell cycle - yeast;K04372//MAPK signaling pathway;Insulin signaling pathway
148979,0,0,0,0,0,0,0,0,24,0,3,0,GLIS1;GLIS family zinc finger 1,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872//metal ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
1490,0,0,1,0,0,0,0,0,43,0,12,0,CTGF;connective tissue growth factor,GO:0005801//cis-Golgi network;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005938//cell cortex;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,GO:0010942//positive regulation of cell death;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0051385//response to mineralocorticoid;GO:0035556//intracellular signal transduction;GO:0010628//positive regulation of gene expression;GO:0010467//gene expression;GO:0046330//positive regulation of JNK cascade;GO:0008284//positive regulation of cell proliferation;GO:0001894//tissue homeostasis;GO:0070278//extracellular matrix constituent secretion;GO:0010629//negative regulation of gene expression;GO:0001558//regulation of cell growth;GO:0009749//response to glucose;GO:0001525//angiogenesis;GO:0060452//positive regulation of cardiac muscle contraction;GO:0072593//reactive oxygen species metabolic process;GO:0060548//negative regulation of cell death;GO:0070542//response to fatty acid;GO:0001934//positive regulation of protein phosphorylation;GO:0010260//organ senescence;GO:0001502//cartilage condensation;GO:0016477//cell migration;GO:0035988//chondrocyte proliferation;GO:0009611//response to wounding;GO:0032355//response to estradiol;GO:0060401//cytosolic calcium ion transport;GO:0008544//epidermis development;GO:0001503//ossification;GO:0044255//cellular lipid metabolic process;GO:0070318//positive regulation of G0 to G1 transition;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043200//response to amino acid;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030324//lung development;GO:0050867//positive regulation of cell activation;GO:0045597//positive regulation of cell differentiation;GO:0007160//cell-matrix adhesion;GO:0006260//DNA replication;GO:0043434//response to peptide hormone;GO:0030154//cell differentiation;GO:0051496//positive regulation of stress fiber assembly;GO:0034059//response to anoxia;GO:0007229//integrin-mediated signaling pathway;GO:0032330//regulation of chondrocyte differentiation,GO:0008083//growth factor activity;GO:0001968//fibronectin binding;GO:0005520//insulin-like growth factor binding;GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0005515//protein binding,-
149013,97,1,1,0,4,0,0,0,26,0,0,0,"NBPF12;neuroblastoma breakpoint family, member 12",GO:0005737//cytoplasm,-,-,K12478//Tuberculosis;Endocytosis;Phagosome
149018,0,0,0,0,17,6,0,0,0,0,0,0,LELP1;late cornified envelope-like proline-rich 1,-,-,-,-
149069,1,0,90,6,54,0,10,111,45,0,13,0,DCDC2B;doublecortin domain containing 2B,-,GO:0035556//intracellular signal transduction,-,-
149076,97,29,0,0,29,0,0,0,21,46,0,0,ZNF362;zinc finger protein 362,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
149086,0,0,0,0,0,0,0,0,2,0,0,0,LINC01225;long intergenic non-protein coding RNA 1225,-,-,-,K01581//Glutathione metabolism;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments
149095,0,0,0,22,32,27,11,59,0,0,228,0,DCST1;DC-STAMP domain containing 1,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
1491,0,0,1,10,13,6,42,2,24,0,0,0,CTH;cystathionine gamma-lyase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0034641//cellular nitrogen compound metabolic process;GO:0044524//protein sulfhydration;GO:0000096//sulfur amino acid metabolic process;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006534//cysteine metabolic process;GO:0070814//hydrogen sulfide biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0018272//protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0019346//transsulfuration;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0019344//cysteine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0000098//sulfur amino acid catabolic process;GO:0051289//protein homotetramerization,GO:0044540//L-cystine L-cysteine-lyase (deaminating);GO:0005516//calmodulin binding;GO:0030170//pyridoxal phosphate binding;GO:0004123//cystathionine gamma-lyase activity;GO:0080146//L-cysteine desulfhydrase activity;GO:0047982//homocysteine desulfhydrase activity;GO:0016846//carbon-sulfur lyase activity;GO:0005515//protein binding,"K01758//Sulfur metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Selenocompound metabolism;Cysteine and methionine metabolism;Glycine, serine and threonine metabolism"
149111,64,0,0,0,0,14,10,0,0,0,0,1,CNIH3;cornichon family AMPA receptor auxiliary protein 3,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0045211//postsynaptic membrane;GO:0043198//dendritic shaft;GO:0030054//cell junction,"GO:0042391//regulation of membrane potential;GO:0035556//intracellular signal transduction;GO:0035249//synaptic transmission, glutamatergic;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity",GO:0016247//channel regulator activity,-
149134,26,0,0,0,0,0,0,0,0,0,0,0,LINC01341;long intergenic non-protein coding RNA 1341,-,-,-,-
149175,0,0,0,0,0,0,0,0,31,0,9,0,"MANEAL;mannosidase, endo-alpha-like",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
149233,0,0,0,0,0,11,0,0,21,0,1,0,IL23R;interleukin 23 receptor,GO:0072536//interleukin-23 receptor complex;GO:0043235//receptor complex,GO:0002230//positive regulation of defense response to virus by host;GO:0034341//response to interferon-gamma;GO:0032735//positive regulation of interleukin-12 production;GO:0042510//regulation of tyrosine phosphorylation of Stat1 protein;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0043382//positive regulation of memory T cell differentiation;GO:0042520//positive regulation of tyrosine phosphorylation of Stat4 protein;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0042102//positive regulation of T cell proliferation;GO:0032740//positive regulation of interleukin-17 production;GO:0006954//inflammatory response;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0032819//positive regulation of natural killer cell proliferation;GO:0045672//positive regulation of osteoclast differentiation;GO:0051135//positive regulation of NK T cell activation;GO:0032496//response to lipopolysaccharide;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0050829//defense response to Gram-negative bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0032729//positive regulation of interferon-gamma production;GO:0038155//interleukin-23-mediated signaling pathway;GO:0010535//positive regulation of activation of JAK2 kinase activity,GO:0005143//interleukin-12 receptor binding;GO:0042019//interleukin-23 binding;GO:0042020//interleukin-23 receptor activity,K05065//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
149281,0,0,0,0,0,23,12,0,0,0,0,0,METTL11B;methyltransferase like 11B,GO:0005634//nucleus,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
149297,1,0,0,0,0,0,0,0,12,0,0,0,"FAM78B;family with sequence similarity 78, member B",-,-,-,-
1493,54,0,0,0,0,16,2,0,19,0,5,0,CTLA4;cytotoxic T-lymphocyte-associated protein 4,GO:0005794//Golgi apparatus;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane,GO:0006974//cellular response to DNA damage stimulus;GO:0031295//T cell costimulation;GO:0030889//negative regulation of B cell proliferation;GO:0050777//negative regulation of immune response;GO:0050853//B cell receptor signaling pathway;GO:0006955//immune response;GO:0042130//negative regulation of T cell proliferation;GO:0043065//positive regulation of apoptotic process;GO:0045590//negative regulation of regulatory T cell differentiation,GO:0005515//protein binding,K06538//Rheumatoid arthritis;Autoimmune thyroid disease;Cell adhesion molecules (CAMs);T cell receptor signaling pathway
149345,146,0,0,0,0,0,0,64,28,7,1,0,SHISA4;shisa family member 4,GO:0016021//integral component of membrane,-,-,K10135//p53 signaling pathway
149371,0,1,47,9,77,0,0,19,0,0,5,0,EXOC8;exocyst complex component 8,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0000145//exocyst,GO:0061024//membrane organization;GO:0015031//protein transport;GO:0044267//cellular protein metabolic process;GO:0034613//cellular protein localization;GO:0006887//exocytosis,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
149420,0,0,0,17,26,16,0,86,47,0,4,0,PDIK1L;PDLIM1 interacting kinase 1 like,GO:0005634//nucleus,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
149428,0,0,1,12,12,41,0,0,18,0,2,0,BNIPL;BCL2/adenovirus E1B 19kD interacting protein like,GO:0005634//nucleus;GO:0005829//cytosol,GO:0040009//regulation of growth rate;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding;GO:0042802//identical protein binding,K11447//Transcriptional misregulation in cancer;K01514//Purine metabolism
149461,0,0,0,0,0,29,3,0,14,0,0,0,CLDN19;claudin 19,GO:0005634//nucleus;GO:0043296//apical junction complex;GO:0005737//cytoplasm;GO:0005923//tight junction;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0050896//response to stimulus;GO:0019227//neuronal action potential propagation;GO:0007601//visual perception;GO:0043297//apical junction assembly,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
149465,0,125,40,20,129,0,25,0,93,101,107,0,WDR65;WD repeat domain 65,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
149466,59,0,0,0,20,0,0,2,17,0,0,0,C1orf210;chromosome 1 open reading frame 210,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
149473,0,0,0,0,0,0,0,0,1,0,0,0,CCDC24;coiled-coil domain containing 24,-,-,-,-
149478,53,0,0,0,0,0,0,0,0,0,4,0,BTBD19;BTB (POZ) domain containing 19,-,-,-,-
149483,0,0,0,0,0,0,0,0,19,0,0,0,CCDC17;coiled-coil domain containing 17,-,-,-,-
149499,78,0,0,0,0,5,0,0,38,0,0,0,LRRC71;leucine rich repeat containing 71,-,-,-,K10165//Tuberculosis;NOD-like receptor signaling pathway;Shigellosis
1495,0,136,0,93,266,0,0,0,71,0,12,0,"CTNNA1;catenin (cadherin-associated protein), alpha 1, 102kDa",GO:0005925//focal adhesion;GO:0001669//acrosomal vesicle;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0016342//catenin complex;GO:0005915//zonula adherens;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0005911//cell-cell junction;GO:0030027//lamellipodium,GO:0051149//positive regulation of muscle cell differentiation;GO:0034332//adherens junction organization;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0090136//epithelial cell-cell adhesion;GO:0007406//negative regulation of neuroblast proliferation;GO:0045216//cell-cell junction organization;GO:0071681//cellular response to indole-3-methanol;GO:0031103//axon regeneration;GO:0007163//establishment or maintenance of cell polarity;GO:0034329//cell junction assembly;GO:0043066//negative regulation of apoptotic process;GO:0007568//aging;GO:2000146//negative regulation of cell motility;GO:0042475//odontogenesis of dentin-containing tooth;GO:0016264//gap junction assembly;GO:0042692//muscle cell differentiation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0001541//ovarian follicle development;GO:0034613//cellular protein localization;GO:0008584//male gonad development;GO:2001045//negative regulation of integrin-mediated signaling pathway;GO:0007155//cell adhesion;GO:0051291//protein heterooligomerization;GO:0045880//positive regulation of smoothened signaling pathway;GO:0043297//apical junction assembly;GO:0043627//response to estrogen,GO:0005198//structural molecule activity;GO:0045296//cadherin binding;GO:0051015//actin filament binding;GO:0008013//beta-catenin binding;GO:0045295//gamma-catenin binding;GO:0017166//vinculin binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K05691//Bacterial invasion of epithelial cells;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Endometrial cancer;Leukocyte transendothelial migration;Adherens junction
149563,0,0,0,0,0,0,0,0,0,0,0,123,C1orf64;chromosome 1 open reading frame 64,-,-,-,-
1496,157,0,0,0,0,24,11,4,52,120,10,0,"CTNNA2;catenin (cadherin-associated protein), alpha 2",GO:0005912//adherens junction;GO:0030424//axon;GO:0016323//basolateral plasma membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005913//cell-cell adherens junction;GO:0030027//lamellipodium,GO:0060134//prepulse inhibition;GO:0021942//radial glia guided migration of Purkinje cell;GO:0048813//dendrite morphogenesis;GO:0048854//brain morphogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0051823//regulation of synapse structural plasticity;GO:0051149//positive regulation of muscle cell differentiation;GO:0007409//axonogenesis;GO:0042692//muscle cell differentiation,GO:0045296//cadherin binding;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton,K05691//Bacterial invasion of epithelial cells;Endometrial cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Pathways in cancer;Leukocyte transendothelial migration;Adherens junction
149603,34,35,1,1,13,0,1,0,13,0,0,0,RNF187;ring finger protein 187,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0051865//protein autoubiquitination;GO:0008284//positive regulation of cell proliferation;GO:0070936//protein K48-linked ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process",GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
149620,0,0,0,0,0,0,0,0,36,0,0,0,"CHIAP2;chitinase, acidic pseudogene 2",-,-,-,K01183//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Metabolic pathways
149628,0,0,0,0,0,1,0,0,21,0,0,0,"PYHIN1;pyrin and HIN domain family, member 1",GO:0016607//nuclear speck,GO:0007049//cell cycle,-,K12966//Cytosolic DNA-sensing pathway;K12971//Cytosolic DNA-sensing pathway
149643,0,0,0,0,0,0,0,0,6,0,0,0,SPATA45;spermatogenesis associated 45,-,-,-,-
149647,0,0,0,0,0,16,0,58,17,0,11,0,"FAM71A;family with sequence similarity 71, member A",GO:0005634//nucleus,-,-,-
149685,0,0,0,0,0,0,0,2,7,0,0,0,ADIG;adipogenin,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016021//integral component of membrane,GO:0050872//white fat cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0050873//brown fat cell differentiation,-,-
149699,0,0,0,5,0,0,0,0,0,0,0,0,GTSF1L;gametocyte specific factor 1-like,-,-,GO:0046872//metal ion binding,K02728//Proteasome
1497,0,0,0,0,0,0,19,60,9,0,0,312,"CTNS;cystinosin, lysosomal cystine transporter",GO:0005764//lysosome;GO:0045111//intermediate filament cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005765//lysosomal membrane;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005770//late endosome,GO:0008542//visual learning;GO:0007616//long-term memory;GO:0007625//grooming behavior;GO:0002088//lens development in camera-type eye;GO:0050890//cognition;GO:0006749//glutathione metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0046034//ATP metabolic process;GO:0015811//L-cystine transport;GO:0007628//adult walking behavior;GO:0007420//brain development,GO:0015184//L-cystine transmembrane transporter activity,K12386//Lysosome
149708,0,0,0,0,0,0,1,0,4,0,0,0,WFDC5;WAP four-disulfide core domain 5,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,-
149840,0,0,0,0,29,13,1,0,8,0,0,0,C20orf196;chromosome 20 open reading frame 196,-,-,-,-
1499,0,46,2,92,175,0,0,0,35,168,6,0,"CTNNB1;catenin (cadherin-associated protein), beta 1, 88kDa",GO:0032993//protein-DNA complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0016342//catenin complex;GO:0048471//perinuclear region of cytoplasm;GO:0034750//Scrib-APC-beta-catenin complex;GO:0030057//desmosome;GO:0005923//tight junction;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0030018//Z disc;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005912//adherens junction;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0070369//beta-catenin-TCF7L2 complex;GO:0005813//centrosome;GO:0005913//cell-cell adherens junction;GO:0030027//lamellipodium;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0030054//cell junction;GO:0031528//microvillus membrane;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane;GO:0005654//nucleoplasm;GO:0030877//beta-catenin destruction complex;GO:0045202//synapse;GO:0005916//fascia adherens;GO:0071944//cell periphery;GO:0005915//zonula adherens;GO:0000922//spindle pole;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane,"GO:0071260//cellular response to mechanical stimulus;GO:0045453//bone resorption;GO:0009950//dorsal/ventral axis specification;GO:0030316//osteoclast differentiation;GO:0007160//cell-matrix adhesion;GO:0060492//lung induction;GO:0034097//response to cytokine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003136//negative regulation of heart induction by canonical Wnt signaling pathway;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0045445//myoblast differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0042692//muscle cell differentiation;GO:2000008//regulation of protein localization to cell surface;GO:0045765//regulation of angiogenesis;GO:0060479//lung cell differentiation;GO:0030521//androgen receptor signaling pathway;GO:0050808//synapse organization;GO:0048489//synaptic vesicle transport;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0060070//canonical Wnt signaling pathway;GO:0046686//response to cadmium ion;GO:0048660//regulation of smooth muscle cell proliferation;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0033234//negative regulation of protein sumoylation;GO:0061324//canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation;GO:0042129//regulation of T cell proliferation;GO:0035315//hair cell differentiation;GO:0061198//fungiform papilla formation;GO:0051149//positive regulation of muscle cell differentiation;GO:0001701//in utero embryonic development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0061047//positive regulation of branching involved in lung morphogenesis;GO:0001711//endodermal cell fate commitment;GO:0007155//cell adhesion;GO:0033077//T cell differentiation in thymus;GO:0090279//regulation of calcium ion import;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0035115//embryonic forelimb morphogenesis;GO:0022009//central nervous system vasculogenesis;GO:0001569//patterning of blood vessels;GO:0051145//smooth muscle cell differentiation;GO:0032355//response to estradiol;GO:0072182//regulation of nephron tubule epithelial cell differentiation;GO:2000017//positive regulation of determination of dorsal identity;GO:0009954//proximal/distal pattern formation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0002052//positive regulation of neuroblast proliferation;GO:0035112//genitalia morphogenesis;GO:0010909//positive regulation of heparan sulfate proteoglycan biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0034333//adherens junction assembly;GO:0034394//protein localization to cell surface;GO:1901215//negative regulation of neuron death;GO:0035116//embryonic hindlimb morphogenesis;GO:0001889//liver development;GO:0002089//lens morphogenesis in camera-type eye;GO:0072054//renal outer medulla development;GO:0014010//Schwann cell proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0060789//hair follicle placode formation;GO:0043065//positive regulation of apoptotic process;GO:0051291//protein heterooligomerization;GO:0071363//cellular response to growth factor stimulus;GO:0045603//positive regulation of endothelial cell differentiation;GO:0006915//apoptotic process;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0000578//embryonic axis specification;GO:0007403//glial cell fate determination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048145//regulation of fibroblast proliferation;GO:0060440//trachea formation;GO:0060769//positive regulation of epithelial cell proliferation involved in prostate gland development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031016//pancreas development;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0001840//neural plate development;GO:0072033//renal vesicle formation;GO:0042733//embryonic digit morphogenesis;GO:0030997//regulation of centriole-centriole cohesion;GO:0007398//ectoderm development;GO:0072053//renal inner medulla development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0036023//embryonic skeletal limb joint morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0060484//lung-associated mesenchyme development;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0001708//cell fate specification;GO:0042493//response to drug;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0032331//negative regulation of chondrocyte differentiation;GO:0031069//hair follicle morphogenesis;GO:0044334//canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition;GO:0001764//neuron migration;GO:0045671//negative regulation of osteoclast differentiation;GO:0021819//layer formation in cerebral cortex;GO:0001702//gastrulation with mouth forming second;GO:0016055//Wnt signaling pathway;GO:0043587//tongue morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0060066//oviduct development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048617//embryonic foregut morphogenesis;GO:0035050//embryonic heart tube development;GO:0030902//hindbrain development;GO:0071681//cellular response to indole-3-methanol;GO:0031641//regulation of myelination;GO:0016337//single organismal cell-cell adhesion;GO:0006351//transcription, DNA-templated;GO:0072079//nephron tubule formation;GO:0007494//midgut development;GO:0048599//oocyte development;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0061154//endothelial tube morphogenesis;GO:0030539//male genitalia development;GO:0045087//innate immune response;GO:0030326//embryonic limb morphogenesis;GO:0032481//positive regulation of type I interferon production;GO:0048469//cell maturation;GO:0043410//positive regulation of MAPK cascade",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0070491//repressing transcription factor binding;GO:0030331//estrogen receptor binding;GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0005198//structural molecule activity;GO:0003682//chromatin binding;GO:0070412//R-SMAD binding;GO:0019899//enzyme binding;GO:0035255//ionotropic glutamate receptor binding;GO:0044325//ion channel binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019900//kinase binding;GO:0045294//alpha-catenin binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0050681//androgen receptor binding;GO:0045296//cadherin binding;GO:0019903//protein phosphatase binding;GO:0032403//protein complex binding;GO:0070411//I-SMAD binding;GO:0035257//nuclear hormone receptor binding;GO:0003713//transcription coactivator activity;GO:0046332//SMAD binding,K02105//Tight junction;Bacterial invasion of epithelial cells;HTLV-I infection;Leukocyte transendothelial migration;Endometrial cancer;Pathogenic Escherichia coli infection;Focal adhesion;Thyroid cancer;Melanogenesis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Basal cell carcinoma;Prostate cancer;Wnt signaling pathway;Adherens junction;Colorectal cancer
149934,0,0,0,0,0,0,0,0,10,0,0,0,NCOR1P1;nuclear receptor corepressor 1 pseudogene 1,-,-,-,K04650//Transcriptional misregulation in cancer
149951,0,0,0,22,43,9,0,0,44,88,0,0,COMMD7;COMM domain containing 7,GO:0070062//extracellular vesicular exosome,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity",GO:0005515//protein binding;GO:0051059//NF-kappaB binding,-
149954,0,0,0,0,0,0,45,14,21,0,8,0,"BPIFB4;BPI fold containing family B, member 4",GO:0005576//extracellular region;GO:0005737//cytoplasm,-,GO:0008289//lipid binding,K02263//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;Cardiac muscle contraction;K05399//Tuberculosis;Toll-like receptor signaling pathway;NF-kappa B signaling pathway;Salmonella infection
149986,0,0,0,0,88,0,33,2,30,0,22,0,"LSM14B;LSM14B, SCD6 homolog B (S. cerevisiae)",GO:0030529//ribonucleoprotein complex,GO:0007275//multicellular organismal development;GO:0006417//regulation of translation,GO:0044822//poly(A) RNA binding,-
149992,1,0,0,0,0,15,43,2,22,0,0,562,ANKRD30BP2;ankyrin repeat domain 30B pseudogene 2,-,-,-,K12460//Neurotrophin signaling pathway;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
149998,0,0,0,0,0,49,0,0,34,0,0,0,"LIPI;lipase, member I",GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0016042//lipid catabolic process,GO:0008201//heparin binding;GO:0004620//phospholipase activity,"K01066//Polycyclic aromatic hydrocarbon degradation;Toluene degradation;Aminobenzoate degradation;Microbial metabolism in diverse environments;Histidine metabolism;Bisphenol degradation;Chlorocyclohexane and chlorobenzene degradation;Limonene and pinene degradation;Tropane, piperidine and pyridine alkaloid biosynthesis;Metabolic pathways;Naphthalene degradation"
15,0,0,0,0,0,15,43,0,0,0,0,0,AANAT;aralkylamine N-acetyltransferase,GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,GO:0046219//indolalkylamine biosynthetic process;GO:0010043//response to zinc ion;GO:0034695//response to prostaglandin E;GO:0009416//response to light stimulus;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0046688//response to copper ion;GO:0034097//response to cytokine;GO:0006474//N-terminal protein amino acid acetylation;GO:0051412//response to corticosterone;GO:0071320//cellular response to cAMP;GO:0030187//melatonin biosynthetic process;GO:0007623//circadian rhythm;GO:0034641//cellular nitrogen compound metabolic process;GO:0051592//response to calcium ion,GO:0004059//aralkylamine N-acetyltransferase activity;GO:0071889//14-3-3 protein binding;GO:0004060//arylamine N-acetyltransferase activity,K00669//Tryptophan metabolism;Metabolic pathways
150,21,0,0,0,0,0,0,0,11,0,0,0,ADRA2A;adrenoceptor alpha 2A,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane,GO:0043268//positive regulation of potassium ion transport;GO:0070473//negative regulation of uterine smooth muscle contraction;GO:0046676//negative regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0035625//epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0051926//negative regulation of calcium ion transport;GO:0032148//activation of protein kinase B activity;GO:0071882//phospholipase C-activating adrenergic receptor signaling pathway;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0032147//activation of protein kinase activity;GO:0050995//negative regulation of lipid catabolic process;GO:0050892//intestinal absorption;GO:0042596//fear response;GO:0071878//negative regulation of adrenergic receptor signaling pathway;GO:0050955//thermoception;GO:0007265//Ras protein signal transduction;GO:0007565//female pregnancy;GO:0042593//glucose homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0006260//DNA replication;GO:0006928//cellular component movement;GO:0019229//regulation of vasoconstriction;GO:0010700//negative regulation of norepinephrine secretion;GO:0045909//positive regulation of vasodilation;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0032870//cellular response to hormone stimulus;GO:0030335//positive regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0071881//adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0090303//positive regulation of wound healing;GO:0007194//negative regulation of adenylate cyclase activity;GO:0030036//actin cytoskeleton organization;GO:0050796//regulation of insulin secretion;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0001819//positive regulation of cytokine production;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0043406//positive regulation of MAP kinase activity;GO:0044281//small molecule metabolic process;GO:0071883//activation of MAPK activity by adrenergic receptor signaling pathway;GO:0032811//negative regulation of epinephrine secretion,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0032795//heterotrimeric G-protein binding;GO:0051379//epinephrine binding;GO:0031996//thioesterase binding;GO:0031696//alpha-2C adrenergic receptor binding;GO:0031692//alpha-1B adrenergic receptor binding;GO:0019901//protein kinase binding;GO:0004938//alpha2-adrenergic receptor activity;GO:0051380//norepinephrine binding,K04138//Neuroactive ligand-receptor interaction
1500,0,48,0,52,158,0,0,0,8,0,0,0,"CTNND1;catenin (cadherin-associated protein), delta 1",GO:0005829//cytosol;GO:0030496//midbody;GO:0005915//zonula adherens;GO:0005634//nucleus;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030027//lamellipodium;GO:0043197//dendritic spine;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0030426//growth cone,"GO:0007155//cell adhesion;GO:0007420//brain development;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0034332//adherens junction organization;GO:0016055//Wnt signaling pathway;GO:0045216//cell-cell junction organization",GO:0005102//receptor binding;GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0019901//protein kinase binding,K05690//Leukocyte transendothelial migration;Adherens junction
150000,0,0,0,0,8,0,0,0,0,0,0,0,"ABCC13;ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding",K05665//ABC transporters;Vitamin digestion and absorption;K05667//ABC transporters;Bile secretion
150082,0,0,51,0,0,18,0,0,20,0,22,645,LCA5L;Leber congenital amaurosis 5-like,-,-,-,-
150084,0,0,0,0,0,0,0,45,0,190,0,0,"IGSF5;immunoglobulin superfamily, member 5",GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0016337//single organismal cell-cell adhesion,GO:0030165//PDZ domain binding,K06786//Epithelial cell signaling in Helicobacter pylori infection;Tight junction
150094,8,0,0,0,9,18,45,0,15,2,0,405,SIK1;salt-inducible kinase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0010830//regulation of myotube differentiation;GO:0045595//regulation of cell differentiation;GO:0043153//entrainment of circadian clock by photoperiod;GO:0035556//intracellular signal transduction;GO:0045721//negative regulation of gluconeogenesis;GO:0010868//negative regulation of triglyceride biosynthetic process;GO:0002028//regulation of sodium ion transport;GO:0055007//cardiac muscle cell differentiation;GO:0007346//regulation of mitotic cell cycle;GO:0007049//cell cycle;GO:2000210//positive regulation of anoikis;GO:0032792//negative regulation of CREB transcription factor activity;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0071889//14-3-3 protein binding;GO:0008140//cAMP response element binding protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
1501,102,1,0,0,28,0,0,0,17,0,20,0,"CTNND2;catenin (cadherin-associated protein), delta 2",GO:0043204//perikaryon;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005912//adherens junction,"GO:0007155//cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0007612//learning;GO:0007275//multicellular organismal development;GO:0048167//regulation of synaptic plasticity;GO:0001763//morphogenesis of a branching structure;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction",GO:0005515//protein binding,K05690//Adherens junction;Leukocyte transendothelial migration
150135,0,0,0,0,0,0,0,0,4,0,0,0,LINC00479;long intergenic non-protein coding RNA 479,-,-,-,-
150147,0,0,0,0,0,8,0,0,10,0,26,0,C21orf128;chromosome 21 open reading frame 128,-,-,-,-
150159,0,38,0,90,257,20,0,0,16,218,144,269,"SLC9B1;solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,GO:0015299//solute:proton antiporter activity,K04482//Homologous recombination;Fanconi anemia pathway;Pathways in cancer;Pancreatic cancer;K09057//Circadian rhythm - fly;K01557//Tyrosine metabolism;Metabolic pathways
150160,0,0,0,0,0,0,0,0,34,246,0,0,"CCT8L2;chaperonin containing TCP1, subunit 8 (theta)-like 2",GO:0005737//cytoplasm,GO:0071805//potassium ion transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0006810//transport;GO:0006820//anion transport,GO:0005253//anion channel activity;GO:0005524//ATP binding;GO:0015269//calcium-activated potassium channel activity,-
150165,0,0,0,0,0,0,0,0,11,0,3,0,"XKR3;XK, Kell blood group complex subunit-related family, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K08008//Leukocyte transendothelial migration;Osteoclast differentiation;Phagosome
150209,212,0,0,0,0,0,59,47,16,250,0,0,"AIFM3;apoptosis-inducing factor, mitochondrion-associated, 3",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,GO:0055114//oxidation-reduction process;GO:0097194//execution phase of apoptosis;GO:0045454//cell redox homeostasis,"GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0051537//2 iron, 2 sulfur cluster binding",K04727//Apoptosis
150221,0,0,0,0,0,2,0,0,8,0,0,0,RIMBP3C;RIMS binding protein 3C,-,-,-,-
150223,0,0,0,0,26,0,2,48,0,0,0,0,YDJC;YdjC homolog (bacterial),-,GO:0005975//carbohydrate metabolic process,"GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",-
150244,0,0,0,1,0,0,0,0,0,0,0,0,"ZDHHC8P1;zinc finger, DHHC-type containing 8 pseudogene 1",-,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
150274,0,1,0,0,15,0,0,0,0,0,0,0,HSCB;HscB mitochondrial iron-sulfur cluster co-chaperone,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005886//plasma membrane,GO:0006457//protein folding;GO:0051259//protein oligomerization;GO:0016226//iron-sulfur cluster assembly,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051087//chaperone binding,-
150275,0,4,0,73,132,0,20,0,26,0,0,0,CCDC117;coiled-coil domain containing 117,-,-,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
150280,0,0,0,0,0,0,0,0,33,0,1,0,HORMAD2;HORMA domain containing 2,GO:0005634//nucleus;GO:0005694//chromosome,GO:0007126//meiotic nuclear division;GO:0051177//meiotic sister chromatid cohesion,-,-
150290,0,0,0,0,0,0,56,0,0,0,0,0,DUSP18;dual specificity phosphatase 18,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0000188//inactivation of MAPK activity,GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
150291,0,0,0,0,0,0,0,0,8,0,0,0,MORC2-AS1;MORC2 antisense RNA 1,-,-,-,-
150297,92,0,0,0,8,0,25,0,37,0,0,0,C22orf42;chromosome 22 open reading frame 42,-,-,-,-
150350,0,0,0,0,0,0,18,0,37,0,23,0,ENTHD1;ENTH domain containing 1,-,-,-,K12471//Endocytosis
150353,0,0,108,48,28,0,0,0,0,0,13,0,"DNAJB7;DnaJ (Hsp40) homolog, subfamily B, member 7",-,-,GO:0051087//chaperone binding,-
150356,65,179,34,67,309,0,23,316,116,0,330,3,CHADL;chondroadherin-like,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,-,-,K06248//Focal adhesion;ECM-receptor interaction;K14319//RNA transport
150365,0,0,0,0,1,0,0,0,71,0,4,0,MEI1;meiosis inhibitor 1,-,GO:0007141//male meiosis I;GO:0007286//spermatid development,-,-
150368,0,0,0,0,1,0,37,0,0,0,3,0,"FAM109B;family with sequence similarity 109, member B",GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle;GO:0055037//recycling endosome;GO:0005802//trans-Golgi network,"GO:0001881//receptor recycling;GO:0042147//retrograde transport, endosome to Golgi;GO:0007032//endosome organization",GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
150372,0,0,0,0,0,22,47,4,87,0,0,43,NFAM1;NFAT activating protein with ITAM motif 1,GO:0045121//membrane raft;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0001819//positive regulation of cytokine production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045577//regulation of B cell differentiation;GO:0035556//intracellular signal transduction;GO:0030183//B cell differentiation;GO:0006954//inflammatory response;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0007165//signal transduction;GO:0050853//B cell receptor signaling pathway,GO:0004888//transmembrane signaling receptor activity,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
150379,0,0,0,0,0,4,21,0,24,0,10,0,PNPLA5;patatin-like phospholipase domain containing 5,-,GO:0016042//lipid catabolic process,GO:0016787//hydrolase activity,K13534//Glycerolipid metabolism;Metabolic pathways
150381,0,0,0,0,0,1,21,0,1,0,0,0,PRR34-AS1;PRR34 antisense RNA 1,-,-,-,-
150383,66,0,0,0,17,0,0,1,0,0,0,0,"CDPF1;cysteine-rich, DPF motif domain containing 1",-,-,-,K02977//Ribosome
1504,82,0,0,0,0,0,0,0,8,0,0,0,CTRB1;chymotrypsinogen B1,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006508//proteolysis;GO:0006766//vitamin metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0030198//extracellular matrix organization;GO:0009235//cobalamin metabolic process;GO:0022617//extracellular matrix disassembly;GO:0007586//digestion,GO:0004252//serine-type endopeptidase activity,K01310//Pancreatic secretion;Protein digestion and absorption
150465,0,0,0,0,12,15,0,0,13,0,0,0,TTL;tubulin tyrosine ligase,-,GO:0006464//cellular protein modification process;GO:0000226//microtubule cytoskeleton organization;GO:0030516//regulation of axon extension,GO:0004835//tubulin-tyrosine ligase activity;GO:0005524//ATP binding,-
150468,0,0,0,0,0,20,0,0,0,0,0,0,CKAP2L;cytoskeleton associated protein 2-like,GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome,-,-,-
150472,2,0,0,36,16,0,2,0,1,0,0,195,CBWD2;COBW domain containing 2,-,-,GO:0005524//ATP binding,-
150483,0,0,36,5,0,0,0,0,22,210,0,0,TEKT4;tektin 4,GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005874//microtubule,GO:0030030//cell projection organization,-,K04688//Insulin signaling pathway;Acute myeloid leukemia;mTOR signaling pathway;TGF-beta signaling pathway;Fc gamma R-mediated phagocytosis;ErbB signaling pathway
150538,82,0,0,0,0,30,14,42,0,0,0,1,SATB2-AS1;SATB2 antisense RNA 1,-,-,-,-
150572,0,0,0,0,0,0,0,0,85,1,0,0,SMYD1;SET and MYND domain containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007507//heart development;GO:0045663//positive regulation of myoblast differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0034968//histone lysine methylation;GO:0010831//positive regulation of myotube differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0018024//histone-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
150590,0,0,0,0,6,0,0,0,0,0,0,0,C2orf15;chromosome 2 open reading frame 15,-,-,GO:0044822//poly(A) RNA binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K11447//Transcriptional misregulation in cancer
1506,0,0,0,11,0,0,12,0,20,0,0,0,CTRL;chymotrypsin-like,GO:0005615//extracellular space,GO:0007586//digestion;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K09632//Pancreatic secretion;Protein digestion and absorption
150677,132,20,0,0,0,0,0,0,10,0,0,0,OTOS;otospiralin,GO:0005576//extracellular region,GO:0007605//sensory perception of sound,-,-
150678,60,0,0,4,0,0,0,0,9,0,0,0,MYEOV2;myeloma overexpressed 2,-,-,-,-
150684,5,0,1,1,10,0,0,0,0,0,0,0,COMMD1;copper metabolism (Murr1) domain containing 1,GO:0070062//extracellular vesicular exosome;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0055070//copper ion homeostasis;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0005507//copper ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
150696,47,0,0,0,0,33,23,28,15,0,9,0,PROM2;prominin 2,GO:0042995//cell projection;GO:0044393//microspike;GO:0005887//integral component of plasma membrane;GO:0031528//microvillus membrane;GO:0016323//basolateral plasma membrane;GO:0005929//cilium;GO:0005902//microvillus;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0060170//ciliary membrane;GO:0071914//prominosome;GO:0070062//extracellular vesicular exosome;GO:0045121//membrane raft;GO:0009986//cell surface,GO:0043088//regulation of Cdc42 GTPase activity;GO:0048550//negative regulation of pinocytosis;GO:2000369//regulation of clathrin-mediated endocytosis;GO:2001287//negative regulation of caveolin-mediated endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0031346//positive regulation of cell projection organization,GO:0015485//cholesterol binding,-
150709,60,0,0,0,0,0,15,0,31,0,24,0,ANKAR;ankyrin and armadillo repeat containing,GO:0016021//integral component of membrane,-,-,K08803//Bladder cancer;Pathways in cancer
150726,1,0,19,4,10,0,0,0,69,0,0,0,FBXO41;F-box protein 41,-,-,-,-
150737,0,0,0,0,12,0,0,0,0,0,0,0,TTC30B;tetratricopeptide repeat domain 30B,GO:0030992//intraciliary transport particle B;GO:0005929//cilium,GO:0042073//intraciliary transport;GO:0042384//cilium assembly,GO:0005515//protein binding,-
150759,55,0,0,0,0,0,0,0,0,0,0,0,LINC00342;long intergenic non-protein coding RNA 342,-,-,-,K06467//B cell receptor signaling pathway;Cell adhesion molecules (CAMs);Hematopoietic cell lineage
150763,3,23,21,34,44,0,40,23,61,0,54,0,"GPAT2;glycerol-3-phosphate acyltransferase 2, mitochondrial",GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0006654//phosphatidic acid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0006072//glycerol-3-phosphate metabolic process,GO:0004366//glycerol-3-phosphate O-acyltransferase activity,K00629//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism
150771,0,0,0,0,0,0,36,0,27,91,0,0,"ITPRIPL1;inositol 1,4,5-trisphosphate receptor interacting protein-like 1",GO:0016020//membrane;GO:0016021//integral component of membrane,-,-,-
150776,297,0,0,2,25,0,0,43,24,0,41,1,"LOC150776;sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) pseudogene",-,-,-,K12353//Metabolic pathways;Sphingolipid metabolism
150786,0,0,0,5,19,0,6,50,26,0,32,0,WTH3DI;RAB6C-like,-,-,-,-
1508,0,74,0,33,42,35,0,0,39,0,23,0,CTSB;cathepsin B,GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0005730//nucleolus;GO:0036021//endolysosome lumen;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0050790//regulation of catalytic activity;GO:0042981//regulation of apoptotic process;GO:0097067//cellular response to thyroid hormone stimulus;GO:0022617//extracellular matrix disassembly;GO:0045087//innate immune response;GO:0030198//extracellular matrix organization;GO:0030855//epithelial cell differentiation;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0046697//decidualization;GO:0006508//proteolysis;GO:0002224//toll-like receptor signaling pathway;GO:0030574//collagen catabolic process,GO:0008233//peptidase activity;GO:0005518//collagen binding;GO:0043394//proteoglycan binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding,K01363//Antigen processing and presentation;Lysosome
150864,0,67,0,29,165,9,0,72,49,1,0,0,"FAM117B;family with sequence similarity 117, member B",-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series;K11447//Transcriptional misregulation in cancer
1509,0,0,0,0,0,0,0,0,7,0,0,0,CTSD;cathepsin D,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0042470//melanosome;GO:0043202//lysosomal lumen;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005764//lysosome,GO:0030198//extracellular matrix organization;GO:0000045//autophagic vacuole assembly;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0008219//cell death;GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding,K01379//Tuberculosis;Lysosome
150921,0,0,0,0,0,7,0,0,0,0,0,0,TCF23;transcription factor 23,GO:0005634//nucleus,GO:0007517//muscle organ development;GO:0030154//cell differentiation,GO:0046983//protein dimerization activity,-
150946,0,0,0,0,4,16,30,0,56,0,10,0,"GAREML;GRB2 associated, regulator of MAPK1-like",GO:0070062//extracellular vesicular exosome,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
150962,88,213,57,113,323,0,0,77,62,0,225,0,PUS10;pseudouridylate synthase 10,-,GO:0008033//tRNA processing;GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0003723//RNA binding,-
151,1,0,0,0,0,0,0,0,7,170,9,1,ADRA2B;adrenoceptor alpha 2B,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0035625//epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0003056//regulation of vascular smooth muscle contraction;GO:0045666//positive regulation of neuron differentiation;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0010700//negative regulation of norepinephrine secretion;GO:0032811//negative regulation of epinephrine secretion;GO:0071883//activation of MAPK activity by adrenergic receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007565//female pregnancy;GO:0001525//angiogenesis;GO:0000165//MAPK cascade;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0045777//positive regulation of blood pressure;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0004938//alpha2-adrenergic receptor activity;GO:0051379//epinephrine binding,K04139//Neuroactive ligand-receptor interaction
1510,0,0,0,0,0,29,0,0,12,126,9,0,CTSE;cathepsin E,GO:0005768//endosome;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0016540//protein autoprocessing;GO:0007586//digestion;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0042803//protein homodimerization activity;GO:0004190//aspartic-type endopeptidase activity,K01382//Lysosome
151011,0,31,3,46,110,0,2,139,1,0,0,0,SEPT10;septin 10,GO:0031105//septin complex,GO:0051301//cell division;GO:0007049//cell cycle,GO:0005525//GTP binding,K04557//Parkinson's disease;K13737//Bacterial invasion of epithelial cells
151050,75,26,45,95,198,0,0,0,46,0,28,0,KANSL1L;KAT8 regulatory NSL complex subunit 1-like,GO:0000123//histone acetyltransferase complex,-,-,-
151056,3,0,0,0,0,10,43,33,118,90,0,0,PLB1;phospholipase B1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,"GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0007603//phototransduction, visible light;GO:0046474//glycerophospholipid biosynthetic process;GO:0001523//retinoid metabolic process",GO:0004622//lysophospholipase activity;GO:0004623//phospholipase A2 activity,K14621//Glycerophospholipid metabolism;Ether lipid metabolism;alpha-Linolenic acid metabolism;Arachidonic acid metabolism;Linoleic acid metabolism;Metabolic pathways;Vitamin digestion and absorption
1511,0,0,0,0,0,0,0,0,26,0,2,0,CTSG;cathepsin G,GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0002003//angiotensin maturation;GO:0044267//cellular protein metabolic process;GO:0070946//neutrophil mediated killing of gram-positive bacterium;GO:0050832//defense response to fungus;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0030198//extracellular matrix organization;GO:0044130//negative regulation of growth of symbiont in host;GO:0050778//positive regulation of immune response;GO:0022617//extracellular matrix disassembly,GO:0008201//heparin binding;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity,K01319//Systemic lupus erythematosus;Renin-angiotensin system;Amoebiasis;Neuroactive ligand-receptor interaction;Lysosome
151112,0,0,0,0,0,26,0,0,0,0,9,0,"ZSWIM2;zinc finger, SWIM-type containing 2",-,GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0006915//apoptotic process;GO:0000209//protein polyubiquitination,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0043621//protein self-association;GO:0008270//zinc ion binding,-
151126,4,5,0,0,31,46,27,0,26,0,17,0,ZNF385B;zinc finger protein 385B,GO:0005634//nucleus,GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator,GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K10137//p53 signaling pathway
151174,0,0,0,0,0,4,0,0,12,0,0,1,LOC151174;uncharacterized LOC151174,-,-,-,-
151176,1,0,0,0,0,0,0,31,16,0,0,0,"FAM132B;family with sequence similarity 132, member B",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0019217//regulation of fatty acid metabolic process;GO:0006879//cellular iron ion homeostasis;GO:2000193//positive regulation of fatty acid transport,GO:0005179//hormone activity;GO:0042803//protein homodimerization activity,-
151188,0,0,39,0,27,0,0,0,17,0,12,0,ARL6IP6;ADP-ribosylation factor-like 6 interacting protein 6,GO:0016021//integral component of membrane,-,-,-
151194,0,0,6,6,20,18,1,89,40,30,3,1,METTL21A;methyltransferase like 21A,GO:0005737//cytoplasm,GO:0018022//peptidyl-lysine methylation;GO:0043462//regulation of ATPase activity;GO:0006479//protein methylation,GO:0016279//protein-lysine N-methyltransferase activity;GO:0051117//ATPase binding;GO:0005515//protein binding;GO:0030544//Hsp70 protein binding,-
151195,98,11,15,65,26,31,0,0,26,1,80,0,CCNYL1;cyclin Y-like 1,-,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding,K11447//Transcriptional misregulation in cancer;K05767//Regulation of actin cytoskeleton;Adherens junction
1512,0,0,40,0,21,0,23,0,12,0,10,0,CTSH;cathepsin H,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle;GO:0097208//alveolar lamellar body;GO:0005764//lysosome;GO:0001520//outer dense fiber,GO:0010815//bradykinin catabolic process;GO:0031638//zymogen activation;GO:0002764//immune response-regulating signaling pathway;GO:0002250//adaptive immune response;GO:0001913//T cell mediated cytotoxicity;GO:0019882//antigen processing and presentation;GO:0043066//negative regulation of apoptotic process;GO:0060448//dichotomous subdivision of terminal units involved in lung branching;GO:0030335//positive regulation of cell migration;GO:0010628//positive regulation of gene expression;GO:0043129//surfactant homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0001656//metanephros development;GO:0010634//positive regulation of epithelial cell migration;GO:0010952//positive regulation of peptidase activity;GO:0006508//proteolysis;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0031648//protein destabilization;GO:0070371//ERK1 and ERK2 cascade;GO:0007283//spermatogenesis;GO:0010813//neuropeptide catabolic process;GO:0097067//cellular response to thyroid hormone stimulus;GO:0032526//response to retinoic acid;GO:0033619//membrane protein proteolysis,GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0030108//HLA-A specific activating MHC class I receptor activity;GO:0070324//thyroid hormone binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0030984//kininogen binding;GO:0004177//aminopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0043621//protein self-association;GO:0004175//endopeptidase activity,K01366//Lysosome
151234,0,0,0,12,0,0,8,0,0,0,0,161,"SULT1C2P1;sulfotransferase family, cytosolic, 1C, member 2 pseudogene 1",-,-,-,-
151242,0,0,0,0,0,21,0,70,0,0,0,0,"PPP1R1C;protein phosphatase 1, regulatory (inhibitor) subunit 1C",GO:0005737//cytoplasm,GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0030307//positive regulation of cell growth;GO:0051301//cell division;GO:0043086//negative regulation of catalytic activity;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle,GO:0004864//protein phosphatase inhibitor activity,K08050//Long-term potentiation
151246,1,0,0,0,1,0,0,0,42,0,22,0,SGOL2;shugoshin-like 2 (S. pombe),"GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0030892//mitotic cohesin complex","GO:0051754//meiotic sister chromatid cohesion, centromeric;GO:0000278//mitotic cell cycle",GO:0005515//protein binding,-
151254,0,0,0,0,0,20,74,0,50,0,0,0,"ALS2CR11;amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11",-,-,-,-
151258,0,0,0,0,0,0,0,0,0,0,3,0,"SLC38A11;solute carrier family 38, member 11",GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0006865//amino acid transport,-,-
151278,0,0,0,0,0,14,0,0,29,0,0,0,CCDC140;coiled-coil domain containing 140,-,-,-,-
151295,0,0,0,0,0,12,14,0,6,3,0,0,"SLC23A3;solute carrier family 23, member 3",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
1513,0,0,0,0,0,0,0,0,0,0,10,0,CTSK;cathepsin K,GO:0005615//extracellular space;GO:0036021//endolysosome lumen;GO:0005576//extracellular region,GO:0045453//bone resorption;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0002224//toll-like receptor signaling pathway;GO:0001957//intramembranous ossification;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization;GO:0045087//innate immune response;GO:0022617//extracellular matrix disassembly,GO:0005518//collagen binding;GO:0001968//fibronectin binding;GO:0043394//proteoglycan binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity,K01371//Toll-like receptor signaling pathway;Lysosome;Osteoclast differentiation;Rheumatoid arthritis
151313,0,0,0,0,0,0,43,1,19,0,0,0,FAHD2B;fumarylacetoacetate hydrolase domain containing 2B,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K01557//Metabolic pathways;Tyrosine metabolism
151325,0,0,0,0,0,0,17,2,17,0,0,0,MYADML;myeloid-associated differentiation marker-like (pseudogene),-,-,-,-
151354,0,19,2,61,561,0,11,0,47,0,3,0,"FAM84A;family with sequence similarity 84, member A",-,-,-,-
151393,0,0,0,14,0,0,24,0,10,0,0,0,RMDN2;regulator of microtubule dynamics 2,GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,-
1514,0,0,0,0,0,0,1,39,17,0,0,0,CTSL;cathepsin L,GO:0043202//lysosomal lumen;GO:0005634//nucleus;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0036021//endolysosome lumen,GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0006508//proteolysis;GO:0002224//toll-like receptor signaling pathway;GO:0019882//antigen processing and presentation;GO:0002250//adaptive immune response;GO:0030574//collagen catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0071888//macrophage apoptotic process;GO:0045087//innate immune response;GO:0097067//cellular response to thyroid hormone stimulus;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization,GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0043394//proteoglycan binding;GO:0001968//fibronectin binding;GO:0005518//collagen binding,K01365//Antigen processing and presentation;Lysosome;Rheumatoid arthritis;Phagosome
151449,0,0,0,0,0,13,19,0,26,0,6,0,GDF7;growth differentiation factor 7,GO:0005615//extracellular space,"GO:0048608//reproductive structure development;GO:0030509//BMP signaling pathway;GO:0007411//axon guidance;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060571//morphogenesis of an epithelial fold;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021527//spinal cord association neuron differentiation;GO:0030855//epithelial cell differentiation;GO:0040007//growth;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0022612//gland morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0048853//forebrain morphogenesis;GO:0030901//midbrain development",GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity,K04664//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
151473,0,0,0,10,3,0,21,0,18,131,3,0,"SLC16A14;solute carrier family 16, member 14",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
151477,0,0,0,0,0,0,19,0,13,0,0,0,LINC00471;long intergenic non-protein coding RNA 471,-,-,-,K05052//Neuroactive ligand-receptor interaction;K11294//Pathogenic Escherichia coli infection
151484,57,0,0,0,0,0,0,0,0,0,16,0,LOC151484;uncharacterized LOC151484,-,-,-,-
1515,0,0,0,0,0,0,22,0,37,0,0,0,CTSV;cathepsin V,GO:0043204//perikaryon;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0043005//neuron projection;GO:0005902//microvillus;GO:0043202//lysosomal lumen;GO:0031410//cytoplasmic vesicle,GO:0051384//response to glucocorticoid;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0031069//hair follicle morphogenesis;GO:0030198//extracellular matrix organization;GO:0009749//response to glucose;GO:0034698//response to gonadotropin;GO:0009267//cellular response to starvation;GO:0022617//extracellular matrix disassembly;GO:0010259//multicellular organismal aging;GO:0010839//negative regulation of keratinocyte proliferation;GO:0007283//spermatogenesis;GO:0046697//decidualization;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0042637//catagen;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0021675//nerve development;GO:0060008//Sertoli cell differentiation;GO:0048102//autophagic cell death,GO:0032403//protein complex binding;GO:0042277//peptide binding;GO:0030984//kininogen binding;GO:0004177//aminopeptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0042393//histone binding,K01375//Lysosome;K01365//Lysosome;Antigen processing and presentation;Rheumatoid arthritis;Phagosome
151507,0,0,0,0,17,0,0,0,51,0,1,0,MSL3P1;male-specific lethal 3 homolog (Drosophila) pseudogene 1,GO:0005634//nucleus,"GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
151525,0,0,0,12,0,24,0,112,11,0,0,0,"WDSUB1;WD repeat, sterile alpha motif and U-box domain containing 1",-,GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity,K12602//RNA degradation;K02084//Huntington's disease;Parkinson's disease;Legionellosis;Tuberculosis;Small cell lung cancer;Apoptosis;Alzheimer's disease;Amyotrophic lateral sclerosis (ALS);p53 signaling pathway
151531,0,0,0,0,0,0,0,0,19,1,0,0,UPP2;uridine phosphorylase 2,GO:0005829//cytosol;GO:0045098//type III intermediate filament,GO:0044281//small molecule metabolic process;GO:0009116//nucleoside metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0046108//uridine metabolic process;GO:0044206//UMP salvage;GO:0046135//pyrimidine nucleoside catabolic process;GO:0009166//nucleotide catabolic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0004850//uridine phosphorylase activity,K00757//Drug metabolism - other enzymes;Pyrimidine metabolism;ABC transporters;Metabolic pathways
151556,6,19,0,0,28,13,0,0,62,0,20,0,GPR155;G protein-coupled receptor 155,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0050890//cognition,-,K11447//Transcriptional misregulation in cancer
151613,0,0,0,0,0,13,28,0,0,0,0,0,TTC14;tetratricopeptide repeat domain 14,-,-,GO:0003723//RNA binding,K09553//Prion diseases
151636,222,52,0,106,262,0,33,0,43,0,61,1,"DTX3L;deltex 3 like, E3 ubiquitin ligase",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006974//cellular response to DNA damage stimulus;GO:0010390//histone monoubiquitination;GO:0006302//double-strand break repair,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0042393//histone binding,K06058//Notch signaling pathway
151647,0,0,0,0,0,11,0,0,0,0,15,1,"FAM19A4;family with sequence similarity 19 (chemokine (C-C motif)-like), member A4",GO:0005576//extracellular region,-,-,-
151648,0,0,0,0,0,0,0,0,17,0,0,0,SGOL1;shugoshin-like 1 (S. pombe),"GO:0000776//kinetochore;GO:0000779//condensed chromosome, centromeric region;GO:0000777//condensed chromosome kinetochore;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0030892//mitotic cohesin complex;GO:0000922//spindle pole",GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0010457//centriole-centriole cohesion;GO:0007059//chromosome segregation;GO:0045132//meiotic chromosome segregation;GO:0008608//attachment of spindle microtubules to kinetochore,GO:0005515//protein binding;GO:0019900//kinase binding,K11580//Oocyte meiosis
151649,0,47,151,233,386,0,0,0,11,274,123,0,PP2D1;protein phosphatase 2C-like domain containing 1,-,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
151651,0,0,0,0,0,0,0,0,6,0,2,0,"EFHB;EF-hand domain family, member B",-,-,GO:0005509//calcium ion binding,K02183//Insulin signaling pathway;Phototransduction;Phosphatidylinositol signaling system;GnRH signaling pathway;Dopaminergic synapse;Long-term potentiation;Alcoholism;Pertussis;Tuberculosis;Vascular smooth muscle contraction;Oocyte meiosis;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Neurotrophin signaling pathway;Alzheimer's disease;Melanogenesis;Gastric acid secretion;Glioma
1517,0,0,0,0,0,0,0,0,0,43,0,0,CTSLP2;cathepsin L pseudogene 2,-,-,-,K01365//Phagosome;Rheumatoid arthritis;Antigen processing and presentation;Lysosome
151742,92,24,0,0,0,0,0,0,6,0,5,0,"PPM1L;protein phosphatase, Mg2+/Mn2+ dependent, 1L",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030148//sphingolipid biosynthetic process;GO:0006470//protein dephosphorylation;GO:0000165//MAPK cascade;GO:0006665//sphingolipid metabolic process,GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity,K04461//MAPK signaling pathway
151790,0,13,0,0,0,20,0,0,15,0,0,283,WDR49;WD repeat domain 49,-,-,-,K10260//Ubiquitin mediated proteolysis;K12857//Spliceosome
1518,0,0,0,0,0,0,10,4,0,0,0,0,CTSLP8;cathepsin L pseudogene 8,-,-,-,K01365//Antigen processing and presentation;Lysosome;Phagosome;Rheumatoid arthritis
151827,0,0,0,2,0,0,0,0,0,0,0,0,LRRC34;leucine rich repeat containing 34,-,-,-,K08727//Epithelial cell signaling in Helicobacter pylori infection;NOD-like receptor signaling pathway;Shigellosis;Pertussis
151835,0,0,0,0,0,2,0,3,79,0,0,0,CPNE9;copine family member IX,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,-,-,K06491//Cell adhesion molecules (CAMs);Prion diseases;K15290//Synaptic vesicle cycle;K02677//B cell receptor signaling pathway;Salivary secretion;Cholinergic synapse;Fc epsilon RI signaling pathway;GABAergic synapse;Tight junction;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;Long-term potentiation;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;African trypanosomiasis;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Amoebiasis;Phototransduction - fly;Wnt signaling pathway;Vascular smooth muscle contraction;Amphetamine addiction;Glutamatergic synapse;Natural killer cell mediated cytotoxicity;Leukocyte transendothelial migration;Calcium signaling pathway;Retrograde endocannabinoid signaling;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Long-term depression;Focal adhesion;VEGF signaling pathway;Glioma;Pathogenic Escherichia coli infection;Gastric acid secretion;Leishmaniasis;Influenza A;Serotonergic synapse;NF-kappa B signaling pathway;Chemokine signaling pathway;GnRH signaling pathway;Pathways in cancer;Gap junction;Dopaminergic synapse;ErbB signaling pathway;Morphine addiction;MAPK signaling pathway
151871,0,0,41,0,0,0,0,0,17,0,6,0,DPPA2;developmental pluripotency associated 2,GO:0005634//nucleus,"GO:2000648//positive regulation of stem cell proliferation;GO:0006351//transcription, DNA-templated;GO:0060484//lung-associated mesenchyme development;GO:0031060//regulation of histone methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0019827//stem cell maintenance",GO:0003676//nucleic acid binding;GO:0003682//chromatin binding,-
151887,88,0,0,0,0,0,0,0,29,0,2,1,CCDC80;coiled-coil domain containing 80,GO:0005614//interstitial matrix;GO:0005604//basement membrane,GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion,GO:0008201//heparin binding;GO:0001968//fibronectin binding,-
151888,0,0,0,0,0,0,0,0,44,0,7,0,BTLA;B and T lymphocyte associated,GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0030889//negative regulation of B cell proliferation;GO:0031295//T cell costimulation;GO:0002768//immune response-regulating cell surface receptor signaling pathway,GO:0004872//receptor activity,-
1519,29,19,0,0,8,0,29,0,5,0,0,0,CTSO;cathepsin O,GO:0005764//lysosome,GO:0006508//proteolysis,GO:0004197//cysteine-type endopeptidase activity,K01374//Lysosome
151903,0,0,0,0,5,0,0,55,8,0,0,0,CCDC12;coiled-coil domain containing 12,-,-,GO:0005515//protein binding,K12871//Spliceosome
151963,0,0,0,0,0,0,0,0,25,0,0,0,MB21D2;Mab-21 domain containing 2,-,-,GO:0032403//protein complex binding,-
151987,0,0,1,53,107,0,0,0,8,0,0,0,"PPP4R2;protein phosphatase 4, regulatory subunit 2",GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030289//protein phosphatase 4 complex,GO:0006464//cellular protein modification process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006397//mRNA processing;GO:0050790//regulation of catalytic activity;GO:0008380//RNA splicing,"GO:0030674//protein binding, bridging;GO:0005515//protein binding;GO:0030362//protein phosphatase type 4 regulator activity",-
152,0,0,0,0,0,0,0,0,11,0,0,0,ADRA2C;adrenoceptor alpha 2C,GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005768//endosome,GO:0050796//regulation of insulin secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007565//female pregnancy;GO:0032811//negative regulation of epinephrine secretion;GO:0071883//activation of MAPK activity by adrenergic receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0044281//small molecule metabolic process;GO:0007596//blood coagulation;GO:0051930//regulation of sensory perception of pain;GO:0006112//energy reserve metabolic process;GO:0010700//negative regulation of norepinephrine secretion;GO:0045907//positive regulation of vasoconstriction;GO:0070473//negative regulation of uterine smooth muscle contraction;GO:0032148//activation of protein kinase B activity;GO:0035625//epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0045666//positive regulation of neuron differentiation,GO:0004938//alpha2-adrenergic receptor activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0051379//epinephrine binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K04140//Neuroactive ligand-receptor interaction
1520,0,19,0,0,0,0,0,0,0,0,0,0,CTSS;cathepsin S,GO:0016020//membrane;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0036021//endolysosome lumen;GO:0005576//extracellular region;GO:0005764//lysosome;GO:0043202//lysosomal lumen,"GO:0002250//adaptive immune response;GO:0006955//immune response;GO:0019882//antigen processing and presentation;GO:0002224//toll-like receptor signaling pathway;GO:0034769//basement membrane disassembly;GO:0030198//extracellular matrix organization;GO:0045087//innate immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030574//collagen catabolic process;GO:0050729//positive regulation of inflammatory response;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0097067//cellular response to thyroid hormone stimulus;GO:0022617//extracellular matrix disassembly;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent",GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0043394//proteoglycan binding;GO:0004197//cysteine-type endopeptidase activity;GO:0001968//fibronectin binding,K01368//Phagosome;Tuberculosis;Antigen processing and presentation;Lysosome
152002,0,0,0,0,0,0,0,0,11,0,0,0,XXYLT1;xyloside xylosyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016763//transferase activity, transferring pentosyl groups",-
152006,65,0,0,14,54,24,0,0,0,0,0,0,RNF38;ring finger protein 38,GO:0036126//sperm flagellum;GO:0005634//nucleus,GO:0016567//protein ubiquitination;GO:0008584//male gonad development,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
152007,190,83,0,40,123,7,0,49,24,39,0,0,GLIPR2;GLI pathogenesis-related 2,GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane,GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0010634//positive regulation of epithelial cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0042803//protein homodimerization activity,-
152015,0,0,0,12,0,0,0,0,27,0,0,0,ROPN1B;rhophilin associated tail protein 1B,GO:0005737//cytoplasm;GO:0031514//motile cilium,GO:0007342//fusion of sperm to egg plasma membrane;GO:0000910//cytokinesis;GO:0016337//single organismal cell-cell adhesion;GO:0030317//sperm motility;GO:0007340//acrosome reaction;GO:0007283//spermatogenesis;GO:0007266//Rho protein signal transduction,GO:0030159//receptor signaling complex scaffold activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
152065,0,0,0,0,0,0,0,0,2,0,0,0,C3orf22;chromosome 3 open reading frame 22,-,-,-,-
152078,0,0,0,8,2,0,0,0,42,0,0,0,C3orf55;chromosome 3 open reading frame 55,-,-,-,K03247//Measles;RNA transport
152098,0,0,0,0,0,21,0,0,30,0,0,32,"ZCWPW2;zinc finger, CW type with PWWP domain 2",-,-,GO:0008270//zinc ion binding,-
1521,0,0,0,3,0,0,0,0,15,0,23,0,CTSW;cathepsin W,GO:0016020//membrane,GO:0006955//immune response;GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity,K08569//Lysosome
152100,0,0,0,1,0,0,0,0,1,0,0,0,CMC1;C-x(9)-C motif containing 1,GO:0005739//mitochondrion,-,GO:0046872//metal ion binding,-
152110,0,0,0,0,0,9,0,0,27,0,0,0,NEK10;NIMA-related kinase 10,GO:1902911//protein kinase complex,GO:0031954//positive regulation of protein autophosphorylation;GO:1902749//regulation of cell cycle G2/M phase transition;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0006468//protein phosphorylation;GO:0043406//positive regulation of MAP kinase activity,GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding,K00924//Limonene and pinene degradation;Fructose and mannose metabolism;Tyrosine metabolism;Metabolic pathways;Aminobenzoate degradation;Pyrimidine metabolism;Ethylbenzene degradation;Benzoate degradation;Microbial metabolism in diverse environments
152118,0,0,0,0,0,10,0,0,0,144,0,0,C3orf79;chromosome 3 open reading frame 79,-,-,-,-
152137,0,42,0,8,22,35,0,0,62,1,0,370,CCDC50;coiled-coil domain containing 50,GO:0005737//cytoplasm,-,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
152138,0,0,0,0,0,0,0,0,12,0,0,0,PYDC2;pyrin domain containing 2,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
152185,73,0,0,0,29,26,54,3,30,0,0,0,SPICE1;spindle and centriole associated protein 1,GO:0005814//centriole;GO:0005819//spindle;GO:0005813//centrosome,GO:0090307//spindle assembly involved in mitosis;GO:0046599//regulation of centriole replication;GO:0051310//metaphase plate congression,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway;K11447//Transcriptional misregulation in cancer
152189,0,0,0,0,0,0,11,0,0,0,0,0,CMTM8;CKLF-like MARVEL transmembrane domain containing 8,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
152195,0,0,0,0,1,0,0,0,42,0,0,0,NUDT16P1;nudix (nucleoside diphosphate linked moiety X)-type motif 16 pseudogene 1,-,-,-,K01529//Purine metabolism
1522,0,0,0,0,0,0,0,0,9,51,0,0,CTSZ;cathepsin Z,GO:0005764//lysosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0002003//angiotensin maturation;GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis;GO:0060441//epithelial tube branching involved in lung morphogenesis,GO:0008234//cysteine-type peptidase activity,K08568//Lysosome
152206,72,0,0,0,0,14,46,0,29,0,0,0,CCDC13;coiled-coil domain containing 13,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
152217,0,0,0,4,20,0,0,70,0,0,0,0,NCBP2-AS2;NCBP2 antisense RNA 2 (head to head),-,-,-,K08098//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
152273,121,0,0,0,11,30,19,158,38,133,14,0,"FGD5;FYVE, RhoGEF and PH domain containing 5",GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum;GO:0001726//ruffle;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0032587//ruffle membrane,GO:0043547//positive regulation of GTPase activity;GO:0007010//cytoskeleton organization;GO:0046847//filopodium assembly;GO:0008360//regulation of cell shape;GO:0043088//regulation of Cdc42 GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0032321//positive regulation of Rho GTPase activity,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding,-
1523,0,66,27,17,130,92,65,34,107,6,22,15,CUX1;cut-like homeobox 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane;GO:0005730//nucleolus,"GO:0050775//positive regulation of dendrite morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042491//auditory receptor cell differentiation;GO:0000301//retrograde transport, vesicle recycling within Golgi;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001822//kidney development;GO:0006351//transcription, DNA-templated;GO:0030324//lung development;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006891//intra-Golgi vesicle-mediated transport","GO:0003682//chromatin binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0030674//protein binding, bridging;GO:0043565//sequence-specific DNA binding",-
152302,0,0,0,0,1,0,0,0,0,0,4,0,CIDECP;cell death-inducing DFFA-like effector c pseudogene,-,-,-,-
152330,9,0,0,0,0,56,5,0,73,0,0,0,CNTN4;contactin 4,GO:0030424//axon;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007420//brain development;GO:0048167//regulation of synaptic plasticity;GO:0045665//negative regulation of neuron differentiation;GO:0031175//neuron projection development;GO:0007409//axonogenesis;GO:0007413//axonal fasciculation;GO:0007158//neuron cell-cell adhesion,-,-
1524,0,0,0,0,0,7,0,146,29,72,0,0,CX3CR1;chemokine (C-X3-C motif) receptor 1,GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0032809//neuronal cell body membrane;GO:0043005//neuron projection,GO:0016032//viral process;GO:0016525//negative regulation of angiogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0009611//response to wounding;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0006935//chemotaxis;GO:0006968//cellular defense response;GO:0070098//chemokine-mediated signaling pathway;GO:0021795//cerebral cortex cell migration;GO:0007155//cell adhesion;GO:0048246//macrophage chemotaxis;GO:0045766//positive regulation of angiogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030336//negative regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002282//microglial cell activation involved in immune response,GO:0005515//protein binding;GO:0004950//chemokine receptor activity;GO:0016495//C-X3-C chemokine receptor activity,K04192//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
152404,155,0,0,0,0,12,27,31,0,0,0,0,"IGSF11;immunoglobulin superfamily, member 11",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0040008//regulation of growth;GO:0007155//cell adhesion,-,-
152405,0,0,0,0,0,0,0,0,23,0,0,0,C3orf30;chromosome 3 open reading frame 30,-,-,-,-
152485,22,102,0,55,129,0,8,0,60,0,0,0,ZNF827;zinc finger protein 827,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
1525,0,0,0,0,0,8,0,0,27,0,0,0,CXADR;coxsackie virus and adenovirus receptor,GO:0005923//tight junction;GO:0001669//acrosomal vesicle;GO:0016327//apicolateral plasma membrane;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0005911//cell-cell junction;GO:0044297//cell body;GO:0030426//growth cone;GO:0031594//neuromuscular junction;GO:0030175//filopodium;GO:0005576//extracellular region;GO:0014704//intercalated disc;GO:0043005//neuron projection,GO:0007507//heart development;GO:0048739//cardiac muscle fiber development;GO:0045216//cell-cell junction organization;GO:0010669//epithelial structure maintenance;GO:0086067//AV node cell to bundle of His cell communication;GO:0046629//gamma-delta T cell activation;GO:0009615//response to virus;GO:0031532//actin cytoskeleton reorganization;GO:0030593//neutrophil chemotaxis;GO:0034109//homotypic cell-cell adhesion;GO:0008354//germ cell migration;GO:0007005//mitochondrion organization;GO:0050900//leukocyte migration;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0050776//regulation of immune response;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0070633//transepithelial transport;GO:0007596//blood coagulation,GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005102//receptor binding;GO:0030165//PDZ domain binding;GO:0001618//virus receptor activity;GO:0071253//connexin binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0008013//beta-catenin binding,K06788//Viral myocarditis
152503,238,20,1,39,161,14,0,44,13,0,0,0,SH3D19;SH3 domain containing 19,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006892//post-Golgi vesicle-mediated transport;GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0061024//membrane organization;GO:0051044//positive regulation of membrane protein ectodomain proteolysis,GO:0005515//protein binding;GO:0070064//proline-rich region binding,K12470//Endocytosis;K13738//Bacterial invasion of epithelial cells
152518,100,51,52,50,86,11,0,0,100,0,104,0,"NFXL1;nuclear transcription factor, X-box binding-like 1",GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0016020//membrane,"GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
152519,0,0,0,0,2,15,40,0,11,0,0,0,NIPAL1;NIPA-like domain containing 1,GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation
152559,0,0,1,18,5,0,0,0,6,0,0,0,PAQR3;progestin and adipoQ receptor family member III,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0001933//negative regulation of protein phosphorylation;GO:0034067//protein localization to Golgi apparatus;GO:0043407//negative regulation of MAP kinase activity;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0010977//negative regulation of neuron projection development,GO:0004872//receptor activity,K07297//Adipocytokine signaling pathway
152573,0,0,0,0,0,8,0,0,6,0,6,0,SHISA3;shisa family member 3,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007275//multicellular organismal development,-,-
152579,73,0,0,10,11,44,19,0,9,0,0,0,SCFD2;sec1 family domain containing 2,-,GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport,-,-
152641,0,0,0,0,0,29,0,8,16,0,8,0,WWC2-AS2;WWC2 antisense RNA 2,-,-,-,-
152687,0,0,0,4,15,14,0,0,35,0,0,0,ZNF595;zinc finger protein 595,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1527,6,0,0,0,0,0,0,1,2,0,0,62,TEX28;testis expressed 28,GO:0016021//integral component of membrane,-,-,-
152756,0,0,0,0,10,0,7,0,0,0,0,0,"FAM218A;family with sequence similarity 218, member A",-,-,-,-
152789,0,0,0,0,0,15,39,0,28,34,6,0,JAKMIP1;janus kinase and microtubule interacting protein 1,GO:0030529//ribonucleoprotein complex;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane,GO:0015031//protein transport;GO:0050890//cognition,GO:0050811//GABA receptor binding;GO:0019900//kinase binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding,-
1528,0,50,1,22,95,0,0,1,0,0,0,0,CYB5A;cytochrome b5 type A (microsomal),GO:0005789//endoplasmic reticulum membrane;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0019852//L-ascorbic acid metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process,GO:0046872//metal ion binding;GO:0004033//aldo-keto reductase (NADP) activity;GO:0020037//heme binding;GO:0004129//cytochrome-c oxidase activity;GO:0019899//enzyme binding,K10226//PPAR signaling pathway;Biosynthesis of unsaturated fatty acids;alpha-Linolenic acid metabolism
152815,0,0,0,0,60,0,0,0,35,0,0,0,THAP6;THAP domain containing 6,GO:0015630//microtubule cytoskeleton,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation
152816,217,0,0,0,0,0,0,0,15,0,13,0,C4orf26;chromosome 4 open reading frame 26,GO:0005576//extracellular region,-,-,K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;Metabolic pathways;beta-Alanine metabolism;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
152831,0,0,0,0,4,15,15,0,69,0,4,0,KLB;klotho beta,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0005975//carbohydrate metabolic process;GO:0045087//innate immune response,"GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",K14756//Endocrine and other factor-regulated calcium reabsorption;Starch and sucrose metabolism;Metabolic pathways;Pentose and glucuronate interconversions
152877,0,0,0,0,0,26,32,0,34,0,0,0,"FAM53A;family with sequence similarity 53, member A",GO:0005634//nucleus,-,-,-
152926,17,68,0,67,152,22,16,0,79,0,39,0,"PPM1K;protein phosphatase, Mg2+/Mn2+ dependent, 1K",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006470//protein dephosphorylation,GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity,K04461//MAPK signaling pathway
152992,14,0,0,0,0,0,0,0,0,0,0,0,TRMT44;tRNA methyltransferase 44 homolog (S. cerevisiae),GO:0005737//cytoplasm,GO:0032259//methylation;GO:0008033//tRNA processing,GO:0008168//methyltransferase activity;GO:0046872//metal ion binding,-
153,0,0,0,2,0,0,0,0,5,121,0,0,ADRB1;adrenoceptor beta 1,GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane,GO:0045986//negative regulation of smooth muscle contraction;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0051924//regulation of calcium ion transport;GO:0035811//negative regulation of urine volume;GO:0031649//heat generation;GO:0001996//positive regulation of heart rate by epinephrine-norepinephrine;GO:0007613//memory;GO:0007568//aging;GO:0002024//diet induced thermogenesis;GO:0019233//sensory perception of pain;GO:0009409//response to cold;GO:0086004//regulation of cardiac muscle cell contraction;GO:0042596//fear response;GO:0003061//positive regulation of the force of heart contraction by norepinephrine;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0043065//positive regulation of apoptotic process;GO:0033365//protein localization to organelle;GO:0005980//glycogen catabolic process;GO:0050873//brown fat cell differentiation;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:2001259//positive regulation of cation channel activity;GO:0006915//apoptotic process;GO:0032320//positive regulation of Ras GTPase activity;GO:0007266//Rho protein signal transduction;GO:0002025//vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure;GO:0046878//positive regulation of saliva secretion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:1900135//positive regulation of renin secretion into blood stream;GO:0042060//wound healing;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0055088//lipid homeostasis,GO:0051380//norepinephrine binding;GO:0008144//drug binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0035240//dopamine binding;GO:0005057//receptor signaling protein activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0051379//epinephrine binding;GO:0030165//PDZ domain binding;GO:0004940//beta1-adrenergic receptor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K04141//Neuroactive ligand-receptor interaction;Salivary secretion;Dilated cardiomyopathy;Calcium signaling pathway;Endocytosis;Gap junction
153020,0,0,0,0,0,0,0,0,22,0,0,0,"RASGEF1B;RasGEF domain family, member 1B",GO:0005770//late endosome;GO:0005769//early endosome;GO:0030496//midbody,GO:0032320//positive regulation of Ras GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005088//Ras guanyl-nucleotide exchange factor activity,K06277//Insulin signaling pathway;Neurotrophin signaling pathway;Renal cell carcinoma;Focal adhesion;K07376//Salivary secretion;Olfactory transduction;Long-term depression;Vascular smooth muscle contraction;Gap junction;K08018//MAPK signaling pathway
153090,37,0,0,0,26,17,29,9,22,5,31,380,DAB2IP;DAB2 interacting protein,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005737//cytoplasm;GO:0044301//climbing fiber;GO:0043025//neuronal cell body;GO:0044300//cerebellar mossy fiber;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0030424//axon;GO:0032809//neuronal cell body membrane;GO:1990032//parallel fiber;GO:0030139//endocytic vesicle,"GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0010633//negative regulation of epithelial cell migration;GO:0046330//positive regulation of JNK cascade;GO:0043410//positive regulation of MAPK cascade;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071158//positive regulation of cell cycle arrest;GO:0045087//innate immune response;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0001525//angiogenesis;GO:0021819//layer formation in cerebral cortex;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043254//regulation of protein complex assembly;GO:0010596//negative regulation of endothelial cell migration;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0006986//response to unfolded protein;GO:0046580//negative regulation of Ras protein signal transduction;GO:0032312//regulation of ARF GTPase activity;GO:0043553//negative regulation of phosphatidylinositol 3-kinase activity;GO:0034260//negative regulation of GTPase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006927//transformed cell apoptotic process;GO:0048812//neuron projection morphogenesis;GO:0043407//negative regulation of MAP kinase activity;GO:0032320//positive regulation of Ras GTPase activity;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0001933//negative regulation of protein phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0044257//cellular protein catabolic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0034261//negative regulation of Ras GTPase activity;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0035414//negative regulation of catenin import into nucleus;GO:0072577//endothelial cell apoptotic process;GO:0030308//negative regulation of cell growth;GO:0000185//activation of MAPKKK activity;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0007049//cell cycle;GO:0071347//cellular response to interleukin-1;GO:1900744//regulation of p38MAPK cascade;GO:0007252//I-kappaB phosphorylation;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:2001224//positive regulation of neuron migration;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0036324//vascular endothelial growth factor receptor-2 signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0090129//positive regulation of synapse maturation;GO:0045732//positive regulation of protein catabolic process;GO:2000599//negative regulation of cyclin catabolic process;GO:0043507//positive regulation of JUN kinase activity;GO:1900006//positive regulation of dendrite development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035148//tube formation;GO:0007257//activation of JUN kinase activity;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0021814//cell motility involved in cerebral cortex radial glia guided migration;GO:0048147//negative regulation of fibroblast proliferation;GO:0050680//negative regulation of epithelial cell proliferation;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0070317//negative regulation of G0 to G1 transition;GO:0010976//positive regulation of neuron projection development",GO:0035591//signaling adaptor activity;GO:0005515//protein binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0035662//Toll-like receptor 4 binding;GO:0042802//identical protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0019901//protein kinase binding;GO:0005123//death receptor binding;GO:0047485//protein N-terminus binding;GO:0036312//phosphatidylinositol 3-kinase regulatory subunit binding;GO:0005099//Ras GTPase activator activity;GO:0042803//protein homodimerization activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0071889//14-3-3 protein binding;GO:0051721//protein phosphatase 2A binding;GO:0019900//kinase binding;GO:0017124//SH3 domain binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0032403//protein complex binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding,K04352//Axon guidance;MAPK signaling pathway
153129,0,0,0,0,0,18,18,0,49,0,0,0,"SLC38A9;solute carrier family 38, member 9",GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0006865//amino acid transport,-,-
153201,0,0,0,0,0,0,0,66,59,117,15,0,"SLC36A2;solute carrier family 36 (proton/amino acid symporter), member 2",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0015808//L-alanine transport;GO:0015816//glycine transport;GO:0006865//amino acid transport;GO:0006811//ion transport;GO:0035524//proline transmembrane transport;GO:0015992//proton transport,GO:0015187//glycine transmembrane transporter activity;GO:0005280//hydrogen:amino acid symporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity,K14209//Protein digestion and absorption
153218,0,0,0,0,0,0,0,0,8,0,0,0,"SPINK13;serine peptidase inhibitor, Kazal type 13 (putative)",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity;GO:1902225//negative regulation of acrosome reaction,GO:0004867//serine-type endopeptidase inhibitor activity,-
153222,0,1,0,4,59,58,21,0,84,0,0,0,CREBRF;CREB3 regulatory factor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016604//nuclear body,"GO:0006351//transcription, DNA-templated;GO:1900102//negative regulation of endoplasmic reticulum unfolded protein response;GO:0006810//transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0045732//positive regulation of protein catabolic process;GO:0051222//positive regulation of protein transport;GO:0032388//positive regulation of intracellular transport;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
153241,48,0,0,1,0,9,40,0,51,118,0,37,CEP120;centrosomal protein 120kDa,GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0032880//regulation of protein localization;GO:0022008//neurogenesis;GO:0022027//interkinetic nuclear migration;GO:0021987//cerebral cortex development;GO:0030953//astral microtubule organization;GO:0032886//regulation of microtubule-based process,GO:0008022//protein C-terminus binding,K11423//Lysine degradation;K12478//Tuberculosis;Endocytosis;Phagosome
153328,0,0,0,0,0,0,0,66,11,0,0,0,"SLC25A48;solute carrier family 25, member 48",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport,-,-
153364,0,0,0,9,20,0,0,0,35,0,0,0,MBLAC2;metallo-beta-lactamase domain containing 2,GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,-
153396,0,0,0,16,1,0,0,0,80,0,0,0,TMEM161B;transmembrane protein 161B,GO:0016021//integral component of membrane,-,-,K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption;K15043//Influenza A;K03364//Cell cycle;Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;K04006//Complement and coagulation cascades;Viral myocarditis;Hematopoietic cell lineage
1534,0,0,0,1,0,0,0,0,25,0,0,0,CYB561;cytochrome b561,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0022900//electron transport chain,GO:0022865//transmembrane electron transfer carrier;GO:0046872//metal ion binding;GO:0000293//ferric-chelate reductase activity,-
153443,0,13,0,0,0,15,0,0,24,0,0,0,SRFBP1;serum response factor binding protein 1,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
153469,36,0,0,0,0,0,13,0,7,0,0,0,JAKMIP2-AS1;JAKMIP2 antisense RNA 1,-,-,-,K04006//Complement and coagulation cascades;Viral myocarditis;Hematopoietic cell lineage
153478,0,17,1,13,0,31,1,151,85,0,18,0,"PLEKHG4B;pleckstrin homology domain containing, family G (with RhoGef domain) member 4B",-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
1535,0,0,0,0,0,8,0,0,12,0,0,0,"CYBA;cytochrome b-245, alpha polypeptide",GO:0005739//mitochondrion;GO:0030141//secretory granule;GO:0030670//phagocytic vesicle membrane;GO:0030425//dendrite;GO:0005794//Golgi apparatus;GO:0043020//NADPH oxidase complex;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body,"GO:0042554//superoxide anion generation;GO:0055114//oxidation-reduction process;GO:0031667//response to nutrient levels;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0071480//cellular response to gamma radiation;GO:0071333//cellular response to glucose stimulus;GO:0071260//cellular response to mechanical stimulus;GO:0003106//negative regulation of glomerular filtration by angiotensin;GO:0070555//response to interleukin-1;GO:0045730//respiratory burst;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051701//interaction with host;GO:0006954//inflammatory response;GO:0090382//phagosome maturation;GO:0017004//cytochrome complex assembly;GO:0071356//cellular response to tumor necrosis factor;GO:0030307//positive regulation of cell growth;GO:0050665//hydrogen peroxide biosynthetic process;GO:0001938//positive regulation of endothelial cell proliferation;GO:0014895//smooth muscle hypertrophy;GO:0006801//superoxide metabolic process;GO:0071407//cellular response to organic cyclic compound;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0042493//response to drug;GO:0071230//cellular response to amino acid stimulus",GO:0017124//SH3 domain binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0009055//electron carrier activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0020037//heme binding,K08009//Phagosome;Leishmaniasis;Osteoclast differentiation;Leukocyte transendothelial migration
153527,0,31,0,21,95,34,12,0,11,0,0,0,"ZMAT2;zinc finger, matrin-type 2",GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,K12848//Spliceosome
153562,0,0,0,16,12,10,1,0,19,0,0,0,MARVELD2;MARVEL domain containing 2,GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016021//integral component of membrane;GO:0033010//paranodal junction;GO:0043220//Schmidt-Lanterman incisure;GO:0005923//tight junction;GO:0016323//basolateral plasma membrane,GO:0007605//sensory perception of sound;GO:0061028//establishment of endothelial barrier;GO:0070830//tight junction assembly;GO:0045216//cell-cell junction organization,GO:0005515//protein binding,-
153571,0,0,0,0,0,0,0,0,10,0,0,1,C5orf38;chromosome 5 open reading frame 38,GO:0005576//extracellular region,-,-,-
153572,0,0,0,0,1,0,0,0,16,6,0,0,IRX2;iroquois homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer;K15615//Transcriptional misregulation in cancer
153579,0,0,0,0,0,0,0,2,0,1,8,0,BTNL9;butyrophilin-like 9,GO:0016021//integral component of membrane,-,-,-
1536,0,0,0,0,0,0,22,0,11,0,0,0,"CYBB;cytochrome b-245, beta polypeptide",GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0030670//phagocytic vesicle membrane;GO:0043020//NADPH oxidase complex;GO:0005887//integral component of plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0005739//mitochondrion,"GO:0006811//ion transport;GO:0050665//hydrogen peroxide biosynthetic process;GO:0006801//superoxide metabolic process;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0055114//oxidation-reduction process;GO:0007584//response to nutrient;GO:0042554//superoxide anion generation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034765//regulation of ion transmembrane transport;GO:0045730//respiratory burst;GO:0090382//phagosome maturation;GO:0006954//inflammatory response;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051701//interaction with host",GO:0020037//heme binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0005244//voltage-gated ion channel activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0009055//electron carrier activity,K08008//Leukocyte transendothelial migration;Osteoclast differentiation;Phagosome
153642,0,0,0,0,0,3,0,0,29,34,0,0,"ARSK;arylsulfatase family, member K",GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen,GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process,GO:0046872//metal ion binding;GO:0004065//arylsulfatase activity,-
153643,0,0,0,0,0,0,26,0,0,114,0,0,"FAM81B;family with sequence similarity 81, member B",GO:0005634//nucleus,-,-,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K12478//Tuberculosis;Phagosome;Endocytosis
153657,0,0,0,0,0,21,1,61,36,0,1,0,TTC23L;tetratricopeptide repeat domain 23-like,-,-,-,-
153684,0,0,0,1,22,20,0,0,16,0,11,0,LOC153684;uncharacterized LOC153684,-,-,-,-
1537,0,0,0,9,1,0,0,0,16,22,0,0,CYC1;cytochrome c-1,GO:0016021//integral component of membrane;GO:0070469//respiratory chain;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus,GO:0033762//response to glucagon;GO:0022904//respiratory electron transport chain;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,"GO:0005506//iron ion binding;GO:0045155//electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity;GO:0020037//heme binding",K00413//Two-component system;Metabolic pathways;Oxidative phosphorylation;Alzheimer's disease;Nitrogen metabolism;Huntington's disease;Parkinson's disease;Cardiac muscle contraction
153733,77,0,0,0,11,0,0,0,9,4,0,0,CCDC112;coiled-coil domain containing 112,-,-,-,K06636//Cell cycle - yeast;Cell cycle;Meiosis - yeast;Oocyte meiosis
153743,0,0,0,0,0,1,0,0,38,0,0,0,"PPP1R2P3;protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3",-,GO:0005977//glycogen metabolic process;GO:0009966//regulation of signal transduction;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0043086//negative regulation of catalytic activity,GO:0004864//protein phosphatase inhibitor activity,K12489//Endocytosis
153745,0,0,0,0,0,11,0,0,8,0,0,1,"FAM71B;family with sequence similarity 71, member B",GO:0005634//nucleus,-,-,-
153768,0,0,0,0,0,15,21,0,12,0,0,0,PRELID2;PRELI domain containing 2,GO:0005758//mitochondrial intermembrane space,GO:0015914//phospholipid transport,GO:1990050//phosphatidic acid transporter activity,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
153769,88,1,0,0,12,29,43,38,0,0,0,0,SH3RF2;SH3 domain containing ring finger 2,-,GO:0016567//protein ubiquitination;GO:0010923//negative regulation of phosphatase activity,GO:0004864//protein phosphatase inhibitor activity;GO:0019902//phosphatase binding;GO:0008157//protein phosphatase 1 binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding,-
153770,0,28,0,0,0,0,0,0,0,0,0,0,PLAC8L1;PLAC8-like 1,-,-,-,-
1538,0,0,0,0,0,0,0,0,15,0,0,0,"CYLC1;cylicin, basic protein of sperm head cytoskeleton 1",GO:0005634//nucleus;GO:0043159//acrosomal matrix;GO:0033150//cytoskeletal calyx,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0005200//structural constituent of cytoskeleton;GO:0005198//structural molecule activity,-
153830,0,0,0,18,0,22,0,0,32,0,9,281,RNF145;ring finger protein 145,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
1539,0,0,0,0,0,15,0,0,23,0,0,0,"CYLC2;cylicin, basic protein of sperm head cytoskeleton 2",GO:0005634//nucleus;GO:0033150//cytoskeletal calyx,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,GO:0005200//structural constituent of cytoskeleton,-
153918,0,0,0,0,0,0,0,0,22,0,0,0,"ZC2HC1B;zinc finger, C2HC-type containing 1B",-,-,GO:0046872//metal ion binding,-
154,0,0,0,0,2,0,0,0,10,0,11,0,"ADRB2;adrenoceptor beta 2, surface",GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome;GO:0043235//receptor complex;GO:0005634//nucleus;GO:0016324//apical plasma membrane,GO:0002028//regulation of sodium ion transport;GO:0009409//response to cold;GO:0007190//activation of adenylate cyclase activity;GO:0071875//adrenergic receptor signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0043410//positive regulation of MAPK cascade;GO:0002032//desensitization of G-protein coupled receptor protein signaling pathway by arrestin;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0050873//brown fat cell differentiation;GO:0006898//receptor-mediated endocytosis;GO:0031649//heat generation;GO:0007166//cell surface receptor signaling pathway;GO:0008333//endosome to lysosome transport;GO:0045986//negative regulation of smooth muscle contraction;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:0042312//regulation of vasodilation;GO:0002024//diet induced thermogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002025//vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure;GO:0031398//positive regulation of protein ubiquitination;GO:0030501//positive regulation of bone mineralization,GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0042803//protein homodimerization activity;GO:0008179//adenylate cyclase binding;GO:0051380//norepinephrine binding;GO:0004941//beta2-adrenergic receptor activity,K04142//Salivary secretion;Neuroactive ligand-receptor interaction;Calcium signaling pathway;Endocytosis
1540,105,15,1,15,77,14,27,0,33,0,12,0,CYLD;cylindromatosis (turban tumor syndrome),GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005881//cytoplasmic microtubule,"GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0070536//protein K63-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045087//innate immune response;GO:0007049//cell cycle;GO:0070507//regulation of microtubule cytoskeleton organization;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0002181//cytoplasmic translation;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:0070266//necroptotic process;GO:0007346//regulation of mitotic cell cycle;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0016055//Wnt signaling pathway;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway",GO:0004843//ubiquitin-specific protease activity;GO:0019901//protein kinase binding;GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0008270//zinc ion binding;GO:0003735//structural constituent of ribosome,K08601//RIG-I-like receptor signaling pathway;Osteoclast differentiation
154007,0,0,0,7,51,22,0,0,27,0,14,193,SNRNP48;small nuclear ribonucleoprotein 48kDa (U11/U12),GO:0005689//U12-type spliceosomal complex,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0046872//metal ion binding,-
154043,10,0,1,0,1,0,0,0,23,0,0,0,CNKSR3;CNKSR family member 3,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0010765//positive regulation of sodium ion transport,-,K00901//Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways;Glycerophospholipid metabolism
154064,0,0,0,0,0,0,0,0,0,0,0,463,RAET1L;retinoic acid early transcript 1L,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0006955//immune response;GO:0019882//antigen processing and presentation,-,K07987//Natural killer cell mediated cytotoxicity;K07986//Natural killer cell mediated cytotoxicity
154075,79,0,0,0,0,0,0,0,11,0,15,0,SAMD3;sterile alpha motif domain containing 3,-,-,GO:0005515//protein binding,-
154089,88,0,0,0,0,0,40,0,26,0,12,0,LINC01312;long intergenic non-protein coding RNA 1312,-,-,-,K11447//Transcriptional misregulation in cancer
154091,112,3,91,28,68,0,0,0,64,0,84,0,"SLC2A12;solute carrier family 2 (facilitated glucose transporter), member 12",GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm,GO:0015758//glucose transport;GO:0055085//transmembrane transport,GO:0022891//substrate-specific transmembrane transporter activity,-
154141,28,0,27,9,0,20,0,0,41,0,0,0,MBOAT1;membrane bound O-acyltransferase domain containing 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,"GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups",K13517//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism
154150,74,0,0,0,0,0,0,0,0,0,0,0,HDGFL1;hepatoma derived growth factor-like 1,-,-,-,"K00020//Metabolic pathways;Valine, leucine and isoleucine degradation;Pentose phosphate pathway;Glutathione metabolism"
154197,0,0,0,0,0,0,13,0,0,0,11,0,PNLDC1;poly(A)-specific ribonuclease (PARN)-like domain containing 1,GO:0016021//integral component of membrane;GO:0005634//nucleus,-,GO:0003676//nucleic acid binding,K01148//RNA degradation
154214,0,0,0,11,9,20,0,0,2,0,3,0,RNF217;ring finger protein 217,GO:0016021//integral component of membrane,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
1543,0,0,0,0,0,0,0,0,29,0,0,0,"CYP1A1;cytochrome P450, family 1, subfamily A, polypeptide 1",GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane,GO:0042493//response to drug;GO:0044255//cellular lipid metabolic process;GO:0055093//response to hyperoxia;GO:0060137//maternal process involved in parturition;GO:0044281//small molecule metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0032094//response to food;GO:0009792//embryo development ending in birth or egg hatching;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0010041//response to iron(III) ion;GO:0017143//insecticide metabolic process;GO:0009635//response to herbicide;GO:0055114//oxidation-reduction process;GO:0001666//response to hypoxia;GO:0017144//drug metabolic process;GO:0070988//demethylation;GO:0042359//vitamin D metabolic process;GO:0046677//response to antibiotic;GO:0009308//amine metabolic process;GO:0043010//camera-type eye development;GO:0048565//digestive tract development;GO:0006805//xenobiotic metabolic process;GO:0070365//hepatocyte differentiation;GO:0008283//cell proliferation;GO:0019341//dibenzo-p-dioxin catabolic process;GO:0050665//hydrogen peroxide biosynthetic process;GO:0071407//cellular response to organic cyclic compound;GO:0009615//response to virus;GO:0046685//response to arsenic-containing substance;GO:0009812//flavonoid metabolic process;GO:0007568//aging;GO:0033189//response to vitamin A;GO:0019373//epoxygenase P450 pathway;GO:0009611//response to wounding;GO:0006778//porphyrin-containing compound metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0009624//response to nematode;GO:0009804//coumarin metabolic process;GO:0097267//omega-hydroxylase P450 pathway,"GO:0070576//vitamin D 24-hydroxylase activity;GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0020037//heme binding;GO:0019899//enzyme binding;GO:0032451//demethylase activity;GO:0016491//oxidoreductase activity;GO:0016711//flavonoid 3'-monooxygenase activity;GO:0019825//oxygen binding;GO:0008395//steroid hydroxylase activity;GO:0016679//oxidoreductase activity, acting on diphenols and related substances as donors",K07408//Tryptophan metabolism;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Retinol metabolism;Metabolic pathways
154313,101,0,0,0,9,0,6,0,0,40,0,0,C6orf165;chromosome 6 open reading frame 165,-,-,-,-
1544,0,0,12,0,0,14,0,1,0,168,6,0,"CYP1A2;cytochrome P450, family 1, subfamily A, polypeptide 2",GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0006778//porphyrin-containing compound metabolic process;GO:0071615//oxidative deethylation;GO:0055114//oxidation-reduction process;GO:0042737//drug catabolic process;GO:0010468//regulation of gene expression;GO:0009820//alkaloid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0030324//lung development;GO:0006706//steroid catabolic process;GO:0017144//drug metabolic process;GO:0097267//omega-hydroxylase P450 pathway;GO:0070989//oxidative demethylation;GO:0009791//post-embryonic development;GO:0032787//monocarboxylic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0032355//response to estradiol;GO:0071276//cellular response to cadmium ion;GO:0045333//cellular respiration;GO:0032496//response to lipopolysaccharide;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0046483//heterocycle metabolic process;GO:0050665//hydrogen peroxide biosynthetic process;GO:0016098//monoterpenoid metabolic process;GO:0042738//exogenous drug catabolic process;GO:0044281//small molecule metabolic process;GO:0009403//toxin biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0032259//methylation,"GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0020037//heme binding;GO:0032451//demethylase activity;GO:0019899//enzyme binding;GO:0034875//caffeine oxidase activity;GO:0016491//oxidoreductase activity;GO:0009055//electron carrier activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0004497//monooxygenase activity",K07409//Linoleic acid metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Caffeine metabolism;Metabolism of xenobiotics by cytochrome P450;Tryptophan metabolism;Retinol metabolism
154449,0,0,0,0,0,0,0,0,7,0,0,0,LOC154449;uncharacterized LOC154449,-,-,-,-
154467,0,0,0,4,10,0,0,0,10,0,0,0,CCDC167;coiled-coil domain containing 167,GO:0016021//integral component of membrane,-,-,-
1545,0,2,1,22,27,1,30,0,10,0,0,0,"CYP1B1;cytochrome P450, family 1, subfamily B, polypeptide 1",GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane,GO:0046427//positive regulation of JAK-STAT cascade;GO:0046466//membrane lipid catabolic process;GO:0008202//steroid metabolic process;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0070301//cellular response to hydrogen peroxide;GO:0044281//small molecule metabolic process;GO:0016125//sterol metabolic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0045766//positive regulation of angiogenesis;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0071603//endothelial cell-cell adhesion;GO:0043065//positive regulation of apoptotic process;GO:0055114//oxidation-reduction process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0043542//endothelial cell migration;GO:0006725//cellular aromatic compound metabolic process;GO:0048514//blood vessel morphogenesis;GO:0002930//trabecular meshwork development;GO:0008285//negative regulation of cell proliferation;GO:1901313//positive regulation of gene expression involved in extracellular matrix organization;GO:0071407//cellular response to organic cyclic compound;GO:0030336//negative regulation of cell migration;GO:0030199//collagen fibril organization;GO:0006809//nitric oxide biosynthetic process;GO:0009636//response to toxic substance;GO:0006805//xenobiotic metabolic process;GO:0001525//angiogenesis;GO:0097267//omega-hydroxylase P450 pathway;GO:0042574//retinal metabolic process;GO:0007155//cell adhesion;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0019369//arachidonic acid metabolic process;GO:0008210//estrogen metabolic process;GO:0007601//visual perception;GO:0019373//epoxygenase P450 pathway;GO:0061304//retinal blood vessel morphogenesis;GO:0009404//toxin metabolic process;GO:0042572//retinol metabolic process,"GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0004497//monooxygenase activity",K07410//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Tryptophan metabolism
154661,15,0,0,0,0,4,0,60,19,0,0,0,RUNDC3B;RUN domain containing 3B,-,-,-,K12482//Endocytosis
154664,196,0,0,0,0,70,41,106,178,0,9,1,"ABCA13;ATP-binding cassette, sub-family A (ABC1), member 13",GO:0016021//integral component of membrane,GO:0006810//transport;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity,K05647//ABC transporters
154743,2,14,24,0,25,0,27,0,6,0,0,0,C7orf60;chromosome 7 open reading frame 60,-,GO:0031167//rRNA methylation,GO:0016433//rRNA (adenine) methyltransferase activity,-
154754,0,0,0,0,0,0,0,0,19,0,0,0,"PRSS3P2;protease, serine, 3 pseudogene 2",-,-,-,K01312//Neuroactive ligand-receptor interaction;Influenza A;Protein digestion and absorption;Pancreatic secretion
154761,0,0,0,0,0,1,0,0,9,1,0,0,"LOC154761;family with sequence similarity 115, member C pseudogene",-,-,-,K04257//Olfactory transduction
154790,0,0,0,0,0,17,0,0,12,0,0,0,"CLEC2L;C-type lectin domain family 2, member L",GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
154796,61,0,0,7,78,48,0,0,41,0,21,0,AMOT;angiomotin,GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0009897//external side of plasma membrane;GO:0001726//ruffle;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0001725//stress fiber;GO:0005884//actin filament;GO:0005923//tight junction;GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0030139//endocytic vesicle,GO:0016525//negative regulation of angiogenesis;GO:0043534//blood vessel endothelial cell migration;GO:0051496//positive regulation of stress fiber assembly;GO:0030334//regulation of cell migration;GO:0001702//gastrulation with mouth forming second;GO:0042074//cell migration involved in gastrulation;GO:0003365//establishment of cell polarity involved in ameboidal cell migration;GO:0040019//positive regulation of embryonic development;GO:0006935//chemotaxis;GO:0034613//cellular protein localization;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0035329//hippo signaling;GO:0001701//in utero embryonic development;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007043//cell-cell junction assembly;GO:0001570//vasculogenesis;GO:0045793//positive regulation of cell size;GO:0043116//negative regulation of vascular permeability;GO:0030036//actin cytoskeleton organization;GO:0034260//negative regulation of GTPase activity,GO:0004872//receptor activity;GO:0043532//angiostatin binding;GO:0005515//protein binding,K06104//Tight junction
1548,111,0,1,0,0,11,0,0,0,0,0,0,"CYP2A6;cytochrome P450, family 2, subfamily A, polypeptide 6",GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule,GO:0046226//coumarin catabolic process;GO:0042738//exogenous drug catabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process;GO:0017144//drug metabolic process;GO:0009804//coumarin metabolic process,"GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0008389//coumarin 7-hydroxylase activity",K07411//Drug metabolism - cytochrome P450;Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Drug metabolism - other enzymes;Caffeine metabolism
154807,0,0,0,3,39,23,21,0,47,0,4,0,"VKORC1L1;vitamin K epoxide reductase complex, subunit 1-like 1",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0042373//vitamin K metabolic process;GO:0034599//cellular response to oxidative stress,GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0048038//quinone binding,K05357//Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
154810,0,0,0,0,7,0,0,0,0,0,0,0,AMOTL1;angiomotin like 1,GO:0030054//cell junction;GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0005923//tight junction,GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0035329//hippo signaling;GO:0016055//Wnt signaling pathway;GO:0003365//establishment of cell polarity involved in ameboidal cell migration,GO:0042802//identical protein binding;GO:0005515//protein binding,K06104//Tight junction
154822,0,0,0,0,0,52,3,0,15,0,0,0,LINC00689;long intergenic non-protein coding RNA 689,-,-,-,-
154860,0,0,0,0,0,0,0,0,0,197,8,0,FEZF1-AS1;FEZF1 antisense RNA 1,-,-,-,-
154865,0,0,0,0,0,0,18,0,39,0,19,0,IQUB;IQ motif and ubiquitin domain containing,GO:0001669//acrosomal vesicle;GO:0031514//motile cilium,GO:0007224//smoothened signaling pathway;GO:0060271//cilium morphogenesis,-,-
154872,0,0,0,0,0,1,0,0,0,0,0,0,LOC154872;putative uncharacterized protein LOC154872,-,-,-,-
154881,242,23,0,7,65,0,0,70,78,0,0,0,KCTD7;potassium channel tetramerization domain containing 7,GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0008219//cell death;GO:0051260//protein homooligomerization,-,-
1549,0,0,0,0,0,2,0,0,3,0,1,0,"CYP2A7;cytochrome P450, family 2, subfamily A, polypeptide 7",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity,K07411//Drug metabolism - cytochrome P450;Metabolic pathways;Retinol metabolism;Drug metabolism - other enzymes;Metabolism of xenobiotics by cytochrome P450;Caffeine metabolism
155,0,0,0,0,0,26,0,0,0,0,0,0,ADRB3;adrenoceptor beta 3,GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005634//nucleus;GO:0005886//plasma membrane,"GO:0043410//positive regulation of MAPK cascade;GO:0040015//negative regulation of multicellular organism growth;GO:0046677//response to antibiotic;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0002032//desensitization of G-protein coupled receptor protein signaling pathway by arrestin;GO:0007190//activation of adenylate cyclase activity;GO:0006091//generation of precursor metabolites and energy;GO:0009409//response to cold;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0071875//adrenergic receptor signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0002024//diet induced thermogenesis;GO:0007568//aging;GO:0002025//vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure;GO:0006898//receptor-mediated endocytosis;GO:0042755//eating behavior;GO:0050873//brown fat cell differentiation;GO:0006112//energy reserve metabolic process;GO:0031649//heat generation;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway",GO:0015052//beta3-adrenergic receptor activity;GO:0031699//beta-3 adrenergic receptor binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0051380//norepinephrine binding;GO:0051379//epinephrine binding,K04143//Endocytosis;Salivary secretion;Neuroactive ligand-receptor interaction;Calcium signaling pathway
155006,0,0,0,0,0,0,23,34,8,0,18,0,TMEM213;transmembrane protein 213,GO:0016021//integral component of membrane,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer
155038,0,0,0,0,0,24,0,46,39,0,0,0,"GIMAP8;GTPase, IMAP family member 8",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005525//GTP binding,K05305//Metabolic pathways;Fructose and mannose metabolism;Amino sugar and nucleotide sugar metabolism
155051,0,0,0,0,0,0,12,0,9,0,0,0,"CRYGN;crystallin, gamma N",-,-,-,K01886//Aminoacyl-tRNA biosynthesis;ABC transporters;Metabolic pathways;Ribosome
155054,0,0,0,0,0,0,18,63,19,0,0,0,ZNF425;zinc finger protein 425,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
155060,0,0,0,0,0,0,0,0,3,0,0,0,LOC155060;AI894139 pseudogene,-,-,-,-
155061,2,23,0,0,0,0,0,0,9,22,0,0,ZNF746;zinc finger protein 746,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:1901216//positive regulation of neuron death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
155066,0,2,0,12,31,0,0,0,30,0,0,0,"ATP6V0E2;ATPase, H+ transporting V0 subunit e2","GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0030670//phagocytic vesicle membrane",GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0016049//cell growth;GO:0033572//transferrin transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0008152//metabolic process;GO:0007035//vacuolar acidification,GO:0015078//hydrogen ion transmembrane transporter activity,K02153//Synaptic vesicle cycle;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Metabolic pathways;Oxidative phosphorylation
1551,0,0,0,0,0,0,13,0,0,0,0,0,"CYP3A7;cytochrome P450, family 3, subfamily A, polypeptide 7",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0019825//oxygen binding;GO:0020037//heme binding,K07424//Drug metabolism - other enzymes;Steroid hormone biosynthesis;Metabolic pathways;Drug metabolism - cytochrome P450;Linoleic acid metabolism;Retinol metabolism;Bile secretion;Metabolism of xenobiotics by cytochrome P450
155184,76,0,0,6,7,20,0,0,5,0,0,0,"SLC2A7;solute carrier family 2 (facilitated glucose transporter), member 7",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport,GO:0022891//substrate-specific transmembrane transporter activity,-
155185,26,0,0,0,0,11,0,44,14,0,0,0,AMZ1;archaelysin family metallopeptidase 1,-,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
1553,0,0,0,0,0,0,0,5,0,0,0,0,"CYP2A13;cytochrome P450, family 2, subfamily A, polypeptide 13",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity,K07411//Drug metabolism - cytochrome P450;Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Drug metabolism - other enzymes;Retinol metabolism;Caffeine metabolism
155368,0,0,42,0,1,0,0,0,12,0,0,0,WBSCR27;Williams Beuren syndrome chromosome region 27,-,-,-,-
155370,0,0,0,4,86,0,0,53,0,0,0,0,SBDSP1;Shwachman-Bodian-Diamond syndrome pseudogene 1,-,-,-,K14574//Ribosome biogenesis in eukaryotes
155382,0,0,0,0,0,0,0,3,4,0,5,0,VPS37D;vacuolar protein sorting 37 homolog D (S. cerevisiae),GO:0000813//ESCRT I complex;GO:0031902//late endosome membrane;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome,GO:0019058//viral life cycle;GO:0016032//viral process;GO:0075733//intracellular transport of virus;GO:0019068//virion assembly;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0019082//viral protein processing,-,K12185//Endocytosis
155400,0,10,0,0,12,12,0,0,34,0,0,5,"NSUN5P1;NOP2/Sun domain family, member 5 pseudogene 1",-,GO:0032259//methylation,GO:0003723//RNA binding;GO:0008168//methyltransferase activity,-
155435,3,2,1,8,11,15,0,0,32,0,0,0,RBM33;RNA binding motif protein 33,-,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
155465,0,0,0,0,0,15,0,0,0,0,0,0,AGR3;anterior gradient 3,GO:0005576//extracellular region,-,GO:0002162//dystroglycan binding;GO:0005515//protein binding,K05360//Glutathione metabolism
1555,4,0,0,0,0,18,17,0,13,54,0,0,"CYP2B6;cytochrome P450, family 2, subfamily B, polypeptide 6",GO:0005789//endoplasmic reticulum membrane,GO:0042738//exogenous drug catabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0042180//cellular ketone metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process,"GO:0005506//iron ion binding;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0004497//monooxygenase activity;GO:0020037//heme binding",K07412//Arachidonic acid metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism
1556,0,0,0,0,0,10,80,129,9,0,6,0,"CYP2B7P;cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene",-,-,-,K07412//Arachidonic acid metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism
1557,61,0,0,0,0,0,41,0,0,0,0,0,"CYP2C19;cytochrome P450, family 2, subfamily C, polypeptide 19",GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0097267//omega-hydroxylase P450 pathway;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0017144//drug metabolic process;GO:0046483//heterocycle metabolic process;GO:0008202//steroid metabolic process;GO:0042738//exogenous drug catabolic process;GO:0044281//small molecule metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0006805//xenobiotic metabolic process;GO:0016098//monoterpenoid metabolic process,GO:0005506//iron ion binding;GO:0018676//(S)-limonene 7-monooxygenase activity;GO:0020037//heme binding;GO:0019899//enzyme binding;GO:0016491//oxidoreductase activity;GO:0018675//(S)-limonene 6-monooxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0019825//oxygen binding;GO:0004497//monooxygenase activity;GO:0052741//(R)-limonene 6-monooxygenase activity,K07413//Serotonergic synapse;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Arachidonic acid metabolism;Linoleic acid metabolism;Metabolic pathways;Drug metabolism - cytochrome P450
1559,0,0,0,0,0,3,0,0,3,0,0,0,"CYP2C9;cytochrome P450, family 2, subfamily C, polypeptide 9",GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process;GO:0019627//urea metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0042737//drug catabolic process;GO:0055114//oxidation-reduction process;GO:0097267//omega-hydroxylase P450 pathway;GO:0016098//monoterpenoid metabolic process;GO:0070989//oxidative demethylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0042738//exogenous drug catabolic process;GO:0032787//monocarboxylic acid metabolic process,GO:0008144//drug binding;GO:0034875//caffeine oxidase activity;GO:0020037//heme binding;GO:0018676//(S)-limonene 7-monooxygenase activity;GO:0005506//iron ion binding;GO:0004497//monooxygenase activity;GO:0052741//(R)-limonene 6-monooxygenase activity;GO:0008395//steroid hydroxylase activity;GO:0018675//(S)-limonene 6-monooxygenase activity;GO:0016491//oxidoreductase activity,K07413//Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Serotonergic synapse;Metabolic pathways;Drug metabolism - cytochrome P450;Arachidonic acid metabolism;Linoleic acid metabolism
156,88,4,1,35,47,34,26,68,39,0,2,0,"ADRBK1;adrenergic, beta, receptor kinase 1",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane,GO:0007507//heart development;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0060048//cardiac muscle contraction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0003108//negative regulation of the force of heart contraction by chemical signal;GO:0007202//activation of phospholipase C activity;GO:0045988//negative regulation of striated muscle contraction;GO:0007217//tachykinin receptor signaling pathway;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0031623//receptor internalization;GO:0018105//peptidyl-serine phosphorylation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0033605//positive regulation of catecholamine secretion,GO:0004672//protein kinase activity;GO:0031755//Edg-2 lysophosphatidic acid receptor binding;GO:0005515//protein binding;GO:0004703//G-protein coupled receptor kinase activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0047696//beta-adrenergic receptor kinase activity;GO:0005524//ATP binding,K00910//Morphine addiction;Endocytosis;Glutamatergic synapse;Chemokine signaling pathway;Phototransduction - fly;Olfactory transduction
1562,0,0,0,0,0,0,45,0,28,0,0,0,"CYP2C18;cytochrome P450, family 2, subfamily C, polypeptide 18",GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process,GO:0004497//monooxygenase activity;GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity,K07413//Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Serotonergic synapse;Metabolic pathways;Drug metabolism - cytochrome P450;Linoleic acid metabolism;Arachidonic acid metabolism
1564,0,0,1,0,6,27,0,0,23,0,9,1,"CYP2D7P;cytochrome P450, family 2, subfamily D, polypeptide 7, pseudogene",-,-,-,K07414//Drug metabolism - cytochrome P450;Serotonergic synapse;Metabolism of xenobiotics by cytochrome P450
1565,0,0,15,0,0,0,0,0,0,0,0,0,"CYP2D6;cytochrome P450, family 2, subfamily D, polypeptide 6",GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0090350//negative regulation of cellular organofluorine metabolic process;GO:0009804//coumarin metabolic process;GO:0046483//heterocycle metabolic process;GO:0008202//steroid metabolic process;GO:0017144//drug metabolic process;GO:0009822//alkaloid catabolic process;GO:0042737//drug catabolic process;GO:0055114//oxidation-reduction process;GO:0051100//negative regulation of binding;GO:0009820//alkaloid metabolic process;GO:0033076//isoquinoline alkaloid metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0016098//monoterpenoid metabolic process;GO:0070989//oxidative demethylation,GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity;GO:0008144//drug binding;GO:0004497//monooxygenase activity;GO:0020037//heme binding,K07414//Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Serotonergic synapse
157,0,47,2,79,275,23,14,0,44,0,24,0,"ADRBK2;adrenergic, beta, receptor kinase 2",-,GO:0006468//protein phosphorylation;GO:0031623//receptor internalization;GO:0007165//signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005524//ATP binding;GO:0047696//beta-adrenergic receptor kinase activity;GO:0004672//protein kinase activity;GO:0004703//G-protein coupled receptor kinase activity,K00910//Chemokine signaling pathway;Glutamatergic synapse;Morphine addiction;Endocytosis;Olfactory transduction;Phototransduction - fly
1571,0,0,0,0,13,0,0,0,9,103,0,0,"CYP2E1;cytochrome P450, family 2, subfamily E, polypeptide 1",GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane,GO:0010193//response to ozone;GO:0045471//response to ethanol;GO:0006641//triglyceride metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0046483//heterocycle metabolic process;GO:0008202//steroid metabolic process;GO:0010243//response to organonitrogen compound;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0042493//response to drug;GO:0016098//monoterpenoid metabolic process,"GO:0020037//heme binding;GO:0019899//enzyme binding;GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0004497//monooxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0016491//oxidoreductase activity",K07415//Metabolism of xenobiotics by cytochrome P450;Arachidonic acid metabolism;Linoleic acid metabolism;Metabolic pathways;Drug metabolism - cytochrome P450
1572,0,0,48,0,0,0,11,0,18,127,10,0,"CYP2F1;cytochrome P450, family 2, subfamily F, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0018979//trichloroethylene metabolic process;GO:0018931//naphthalene metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance,"GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0004497//monooxygenase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0070330//aromatase activity",K07416//Metabolism of xenobiotics by cytochrome P450
157285,34,0,0,0,0,12,18,36,45,0,0,0,SGK223;homolog of rat pragma of Rnd2,-,GO:0018108//peptidyl-tyrosine phosphorylation,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,-
1573,0,0,0,0,0,0,45,3,27,0,0,0,"CYP2J2;cytochrome P450, family 2, subfamily J, polypeptide 2",GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0043651//linoleic acid metabolic process;GO:0008016//regulation of heart contraction;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process,"GO:0020037//heme binding;GO:0008405//arachidonic acid 11,12-epoxygenase activity;GO:0071614//linoleic acid epoxygenase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0008404//arachidonic acid 14,15-epoxygenase activity",K07418//Arachidonic acid metabolism;Linoleic acid metabolism;Metabolic pathways;Serotonergic synapse
157310,0,0,0,0,2,5,0,0,0,139,0,0,PEBP4;phosphatidylethanolamine-binding protein 4,GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,-,GO:0005515//protein binding,-
157313,0,0,36,0,0,0,65,0,28,0,0,0,CDCA2;cell division cycle associated 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005694//chromosome;GO:0005730//nucleolus,GO:0007067//mitotic nuclear division;GO:0035307//positive regulation of protein dephosphorylation,-,-
157376,0,0,38,10,0,9,16,1,57,0,0,0,FER1L6-AS2;FER1L6 antisense RNA 2,-,-,-,-
157378,32,27,0,8,0,22,12,0,36,0,0,0,TMEM65;transmembrane protein 65,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,K01183//Starch and sucrose metabolism;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Metabolic pathways
157506,0,13,0,2,0,0,0,0,15,0,7,0,RDH10;retinol dehydrogenase 10 (all-trans),GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0016021//integral component of membrane,"GO:0002138//retinoic acid biosynthetic process;GO:0048703//embryonic viscerocranium morphogenesis;GO:0043584//nose development;GO:0007603//phototransduction, visible light;GO:0043583//ear development;GO:0001656//metanephros development;GO:0001701//in utero embryonic development;GO:0001523//retinoid metabolic process;GO:0060449//bud elongation involved in lung branching;GO:0031076//embryonic camera-type eye development;GO:0042574//retinal metabolic process;GO:0060431//primary lung bud formation;GO:0055114//oxidation-reduction process;GO:0035115//embryonic forelimb morphogenesis;GO:0008406//gonad development;GO:0014032//neural crest cell development;GO:0007601//visual perception;GO:0042572//retinol metabolic process",GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity,K11151//Metabolic pathways;Retinol metabolism
157567,0,0,0,18,7,30,0,73,33,0,0,0,ANKRD46;ankyrin repeat domain 46,GO:0016021//integral component of membrane,-,-,-
157570,0,0,0,0,0,7,64,0,91,0,14,0,ESCO2;establishment of sister chromatid cohesion N-acetyltransferase 2,GO:0005794//Golgi apparatus;GO:0035861//site of double-strand break;GO:0010369//chromocenter;GO:0005654//nucleoplasm;GO:0001741//XY body;GO:0031618//nuclear pericentric heterochromatin;GO:0005634//nucleus;GO:0000785//chromatin,GO:0002244//hematopoietic progenitor cell differentiation;GO:0006302//double-strand break repair;GO:0007059//chromosome segregation;GO:0006275//regulation of DNA replication;GO:0000278//mitotic cell cycle;GO:0034421//post-translational protein acetylation;GO:0071168//protein localization to chromatin,"GO:0046872//metal ion binding;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor",-
157574,0,0,0,0,0,0,0,0,1,0,0,0,FBXO16;F-box protein 16,-,-,-,-
1576,0,0,0,0,0,28,24,0,42,0,0,0,"CYP3A4;cytochrome P450, family 3, subfamily A, polypeptide 4",GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0046483//heterocycle metabolic process;GO:0009822//alkaloid catabolic process;GO:0008202//steroid metabolic process;GO:0042738//exogenous drug catabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0042359//vitamin D metabolic process;GO:0006629//lipid metabolic process;GO:0016098//monoterpenoid metabolic process;GO:0008209//androgen metabolic process;GO:0042737//drug catabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0006706//steroid catabolic process;GO:0070989//oxidative demethylation,"GO:0016491//oxidoreductase activity;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0050649//testosterone 6-beta-hydroxylase activity;GO:0008395//steroid hydroxylase activity;GO:0004497//monooxygenase activity;GO:0070576//vitamin D 24-hydroxylase activity;GO:0005506//iron ion binding;GO:0034875//caffeine oxidase activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0019825//oxygen binding;GO:0005496//steroid binding;GO:0033780//taurochenodeoxycholate 6alpha-hydroxylase activity;GO:0050591//quinine 3-monooxygenase activity;GO:0020037//heme binding;GO:0047638//albendazole monooxygenase activity;GO:0019899//enzyme binding",K07424//Drug metabolism - other enzymes;Steroid hormone biosynthesis;Bile secretion;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Linoleic acid metabolism;Drug metabolism - cytochrome P450;Metabolic pathways
157638,0,0,41,12,81,0,13,1,22,0,27,0,"FAM84B;family with sequence similarity 84, member B",GO:0005886//plasma membrane;GO:0005737//cytoplasm,-,GO:0005515//protein binding,K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
157657,0,0,0,5,0,0,0,0,26,0,0,0,C8orf37;chromosome 8 open reading frame 37,GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
157680,40,42,2,33,189,44,38,29,68,0,34,0,VPS13B;vacuolar protein sorting 13 homolog B (yeast),-,GO:0015031//protein transport,-,-
157695,0,8,0,0,47,0,0,0,28,0,0,0,TDRP;testis development related protein,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007283//spermatogenesis,-,-
157697,0,0,0,0,0,6,22,0,0,0,0,0,ERICH1;glutamate-rich 1,-,-,-,K04573//Amyotrophic lateral sclerosis (ALS)
1577,0,0,0,12,0,0,0,0,22,0,0,0,"CYP3A5;cytochrome P450, family 3, subfamily A, polypeptide 5",GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0008202//steroid metabolic process;GO:0009822//alkaloid catabolic process;GO:0070989//oxidative demethylation;GO:0042737//drug catabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0016491//oxidoreductase activity;GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0004497//monooxygenase activity,K07424//Retinol metabolism;Bile secretion;Metabolism of xenobiotics by cytochrome P450;Drug metabolism - cytochrome P450;Metabolic pathways;Linoleic acid metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis
157724,0,0,0,0,0,1,21,0,24,0,0,0,"SLC7A13;solute carrier family 7 (anionic amino acid transporter), member 13",GO:0016021//integral component of membrane,GO:0003333//amino acid transmembrane transport,GO:0015171//amino acid transmembrane transporter activity,-
157739,0,0,0,0,0,0,0,0,21,0,15,0,TDH;L-threonine dehydrogenase (pseudogene),GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0003824//catalytic activity;GO:0050662//coenzyme binding,"K15789//Glycine, serine and threonine metabolism"
157753,0,0,0,0,6,0,0,0,0,0,12,0,TMEM74;transmembrane protein 74,GO:0031410//cytoplasmic vesicle;GO:0005765//lysosomal membrane;GO:0000421//autophagic vacuole membrane;GO:0016021//integral component of membrane,GO:0006914//autophagy,-,-
157769,0,37,1,43,174,0,0,0,84,0,0,5,"FAM91A1;family with sequence similarity 91, member A1",-,-,-,-
157773,0,0,0,0,0,0,0,0,9,0,0,0,C8orf48;chromosome 8 open reading frame 48,-,-,GO:0005515//protein binding,-
157777,0,42,38,46,110,1,19,47,26,0,23,0,MCMDC2;minichromosome maintenance domain containing 2,-,GO:0006260//DNA replication,GO:0003677//DNA binding;GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
157807,0,1,70,0,0,42,0,0,30,0,12,0,CLVS1;clavesin 1,GO:0005768//endosome;GO:0031901//early endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0005802//trans-Golgi network,GO:0007040//lysosome organization;GO:0006810//transport,"GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005215//transporter activity",-
157848,0,0,0,0,19,0,0,0,0,0,0,0,NKX6-3;NK6 homeobox 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030857//negative regulation of epithelial cell differentiation;GO:0001709//cell fate determination;GO:0002067//glandular epithelial cell differentiation;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
157855,0,0,0,0,0,3,22,0,114,0,0,0,"KCNU1;potassium channel, subfamily U, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0032504//multicellular organism reproduction;GO:0007338//single fertilization;GO:0071805//potassium ion transmembrane transport;GO:0035036//sperm-egg recognition;GO:0034765//regulation of ion transmembrane transport,GO:0005267//potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0060072//large conductance calcium-activated potassium channel activity,K05274//Vascular smooth muscle contraction
157869,0,0,56,0,0,0,24,0,28,0,0,0,"SBSPON;somatomedin B and thrombospondin, type 1 domain containing",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0006955//immune response;GO:0006898//receptor-mediated endocytosis,GO:0030247//polysaccharide binding;GO:0005044//scavenger receptor activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
1579,0,0,48,0,0,0,32,0,25,0,0,0,"CYP4A11;cytochrome P450, family 4, subfamily A, polypeptide 11",GO:0005789//endoplasmic reticulum membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular vesicular exosome,GO:0097267//omega-hydroxylase P450 pathway;GO:0006631//fatty acid metabolic process;GO:0003091//renal water homeostasis;GO:0003095//pressure natriuresis;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0044281//small molecule metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0036101//leukotriene B4 catabolic process;GO:0006691//leukotriene metabolic process;GO:0044255//cellular lipid metabolic process;GO:0032305//positive regulation of icosanoid secretion;GO:0055078//sodium ion homeostasis,GO:0005506//iron ion binding;GO:0018685//alkane 1-monooxygenase activity;GO:0052869//arachidonic acid omega-hydroxylase activity;GO:0020037//heme binding;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0008392//arachidonic acid epoxygenase activity,K07425//Fatty acid metabolism;Retinol metabolism;PPAR signaling pathway;Arachidonic acid metabolism;Vascular smooth muscle contraction;Metabolic pathways
157922,0,0,1,18,16,48,2,5,29,0,0,0,CAMSAP1;calmodulin regulated spectrin-associated protein 1,GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0007010//cytoskeleton organization;GO:0031175//neuron projection development;GO:0022604//regulation of cell morphogenesis,GO:0008017//microtubule binding;GO:0005516//calmodulin binding;GO:0030507//spectrin binding,-
157927,0,0,0,0,0,0,47,0,32,0,0,0,C9orf62;chromosome 9 open reading frame 62,-,-,-,-
157983,0,26,0,0,27,0,75,0,19,0,5,0,C9orf66;chromosome 9 open reading frame 66,-,-,-,K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
158,166,1,0,0,7,0,16,0,0,0,0,1,ADSL;adenylosuccinate lyase,GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0006164//purine nucleotide biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006167//AMP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0042594//response to starvation;GO:0007584//response to nutrient;GO:0051262//protein tetramerization;GO:0014850//response to muscle activity;GO:0001666//response to hypoxia;GO:0006144//purine nucleobase metabolic process;GO:0009060//aerobic respiration;GO:0008152//metabolic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0044208//'de novo' AMP biosynthetic process,"GO:0004018//N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity;GO:0070626//(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity","K01756//Alanine, aspartate and glutamate metabolism;Metabolic pathways;Flagellar assembly;Purine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Ribosome;Biosynthesis of secondary metabolites;Mismatch repair"
1580,62,0,0,0,5,0,0,0,5,0,13,0,"CYP4B1;cytochrome P450, family 4, subfamily B, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0018879//biphenyl metabolic process;GO:0018917//fluorene metabolic process;GO:0042738//exogenous drug catabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0018585//fluorene oxygenase activity;GO:0020037//heme binding;GO:0008144//drug binding,-
158035,17,0,0,0,0,9,0,0,17,0,0,0,LINC00032;long intergenic non-protein coding RNA 32,-,-,-,K14570//Ribosome biogenesis in eukaryotes
158038,0,0,0,0,0,20,18,0,11,0,0,0,LINGO2;leucine rich repeat and Ig domain containing 2,GO:0016021//integral component of membrane,-,-,K07523//Axon guidance
158055,0,19,16,33,78,0,0,82,2,0,80,0,C9orf163;chromosome 9 open reading frame 163,-,-,-,-
158056,0,0,0,0,0,29,21,58,5,7,2,0,MAMDC4;MAM domain containing 4,GO:0016021//integral component of membrane,GO:0015031//protein transport,-,K03173//MAPK signaling pathway;Herpes simplex infection;Osteoclast differentiation;Apoptosis;Protein processing in endoplasmic reticulum;Adipocytokine signaling pathway;Hepatitis C;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Pathways in cancer;NF-kappa B signaling pathway;Small cell lung cancer
158062,0,0,0,0,9,16,15,0,12,0,0,2,LCN6;lipocalin 6,GO:0005576//extracellular region,GO:0007338//single fertilization,-,K01830//Arachidonic acid metabolism;Metabolic pathways
158067,0,0,0,25,12,0,12,66,0,0,30,0,AK8;adenylate kinase 8,GO:0005829//cytosol,GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0021591//ventricular system development,GO:0004017//adenylate kinase activity;GO:0004127//cytidylate kinase activity;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity,K00944//Pyrimidine metabolism;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
1581,0,0,0,0,0,0,0,0,14,1,0,0,"CYP7A1;cytochrome P450, family 7, subfamily A, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006707//cholesterol catabolic process;GO:0044255//cellular lipid metabolic process;GO:0016125//sterol metabolic process;GO:0070857//regulation of bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0071333//cellular response to glucose stimulus;GO:0006699//bile acid biosynthetic process;GO:0071397//cellular response to cholesterol;GO:0055114//oxidation-reduction process;GO:0042632//cholesterol homeostasis,GO:0005506//iron ion binding;GO:0020037//heme binding;GO:0008123//cholesterol 7-alpha-monooxygenase activity,K00489//Steroid hormone biosynthesis;Bile secretion;Primary bile acid biosynthesis;Metabolic pathways;PPAR signaling pathway
158131,0,0,0,0,0,0,0,0,17,0,0,0,"OR1Q1;olfactory receptor, family 1, subfamily Q, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
158135,0,19,0,0,0,0,0,2,59,0,10,0,"TTLL11;tubulin tyrosine ligase-like family, member 11",GO:0005929//cilium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0006464//cellular protein modification process,GO:0016874//ligase activity,"K00273//Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism;Peroxisome;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Metabolic pathways"
158158,0,50,73,201,310,0,20,758,70,0,171,0,RASEF;RAS and EF-hand domain containing,GO:0048471//perinuclear region of cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005525//GTP binding;GO:0005509//calcium ion binding,K07901//Pancreatic secretion
158160,0,0,0,0,0,0,22,1,9,0,14,0,HSD17B7P2;hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2,-,-,-,K13373//Metabolic pathways;Steroid biosynthesis;Steroid hormone biosynthesis
1582,95,0,0,0,0,1,19,46,15,0,0,0,"CYP8B1;cytochrome P450, family 8, subfamily B, polypeptide 1",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0055114//oxidation-reduction process;GO:0006629//lipid metabolic process;GO:0016125//sterol metabolic process,GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0008397//sterol 12-alpha-hydroxylase activity;GO:0033778//7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity;GO:0005506//iron ion binding,K07431//PPAR signaling pathway;Primary bile acid biosynthesis;Metabolic pathways
158219,0,0,0,0,18,0,0,0,2,0,0,0,TTC39B;tetratricopeptide repeat domain 39B,-,-,-,-
158228,0,0,3,1,16,0,0,0,13,0,7,0,"FAM201A;family with sequence similarity 201, member A",-,-,-,-
158234,0,102,36,230,197,0,0,65,23,0,110,0,TRMT10B;tRNA methyltransferase 10 homolog B (S. cerevisiae),-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
158248,67,0,0,0,0,0,33,55,8,168,0,0,TTC16;tetratricopeptide repeat domain 16,-,-,-,K12811//Spliceosome;K12893//Spliceosome;Herpes simplex infection
158293,1,1081,58,634,951,0,40,1003,96,0,1376,2,FAM120AOS;family with sequence similarity 120A opposite strand,-,-,-,-
158297,0,0,0,0,16,0,54,0,18,0,0,0,"FAM154A;family with sequence similarity 154, member A",-,-,GO:0005515//protein binding,K13711//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
1583,68,0,17,0,0,0,0,0,0,0,7,0,"CYP11A1;cytochrome P450, family 11, subfamily A, polypeptide 1",GO:0005739//mitochondrion;GO:0043204//perikaryon;GO:0030061//mitochondrial crista;GO:0005759//mitochondrial matrix,GO:0006703//estrogen biosynthetic process;GO:0071356//cellular response to tumor necrosis factor;GO:0071222//cellular response to lipopolysaccharide;GO:0060014//granulosa cell differentiation;GO:0014037//Schwann cell differentiation;GO:0060992//response to fungicide;GO:0060135//maternal process involved in female pregnancy;GO:0071320//cellular response to cAMP;GO:0050756//fractalkine metabolic process;GO:0051412//response to corticosterone;GO:0071347//cellular response to interleukin-1;GO:0033595//response to genistein;GO:0006805//xenobiotic metabolic process;GO:0021766//hippocampus development;GO:0043279//response to alkaloid;GO:0042359//vitamin D metabolic process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0009651//response to salt stress;GO:0042542//response to hydrogen peroxide;GO:0033197//response to vitamin E;GO:0007617//mating behavior;GO:0017085//response to insecticide;GO:0071375//cellular response to peptide hormone stimulus;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0018958//phenol-containing compound metabolic process;GO:0055114//oxidation-reduction process;GO:0061370//testosterone biosynthetic process;GO:0033327//Leydig cell differentiation;GO:0044281//small molecule metabolic process;GO:0033591//response to L-ascorbic acid;GO:0042493//response to drug;GO:0071236//cellular response to antibiotic;GO:0006700//C21-steroid hormone biosynthetic process;GO:0006701//progesterone biosynthetic process;GO:0016125//sterol metabolic process;GO:0021549//cerebellum development;GO:0018879//biphenyl metabolic process;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0008203//cholesterol metabolic process;GO:0071276//cellular response to cadmium ion;GO:0018963//phthalate metabolic process;GO:0008202//steroid metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0010332//response to gamma radiation,GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0015485//cholesterol binding;GO:0008386//cholesterol monooxygenase (side-chain-cleaving) activity,K00498//Steroid hormone biosynthesis;Metabolic pathways
158326,0,0,0,7,0,45,70,101,116,0,12,365,FREM1;FRAS1 related extracellular matrix 1,GO:0016021//integral component of membrane;GO:0005604//basement membrane,GO:0007154//cell communication;GO:0097094//craniofacial suture morphogenesis;GO:0007160//cell-matrix adhesion,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding,K06560//Phagosome;Tuberculosis
158358,0,1,3,45,81,0,0,0,22,0,12,0,KIAA2026;KIAA2026,-,-,-,K10955//Amoebiasis;Vibrio cholerae infection
158376,0,0,0,5,0,0,0,1,0,0,34,0,LINC00961;long intergenic non-protein coding RNA 961,-,-,-,-
158381,0,0,0,0,0,2,18,114,16,0,3,0,"ATP8B5P;ATPase, class I, type 8B, member 5, pseudogene",-,-,-,K01530//Purine metabolism
158399,0,0,1,26,33,19,22,0,95,0,0,0,ZNF483;zinc finger protein 483,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
1584,0,0,0,0,0,36,24,0,19,0,13,0,"CYP11B1;cytochrome P450, family 11, subfamily B, polypeptide 1",GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0006704//glucocorticoid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0016125//sterol metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0006700//C21-steroid hormone biosynthetic process;GO:0042593//glucose homeostasis;GO:0034651//cortisol biosynthetic process;GO:0008217//regulation of blood pressure;GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0032342//aldosterone biosynthetic process;GO:0006955//immune response;GO:0035865//cellular response to potassium ion,GO:0020037//heme binding;GO:0004507//steroid 11-beta-monooxygenase activity;GO:0005506//iron ion binding,K00497//Metabolic pathways;Steroid hormone biosynthesis;K07433//Metabolic pathways;Steroid hormone biosynthesis
158401,0,0,0,0,16,30,62,0,15,0,11,266,C9orf84;chromosome 9 open reading frame 84,-,-,-,-
158405,61,0,0,9,24,0,0,0,32,0,10,146,KIAA1958;KIAA1958,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
158427,0,49,32,25,104,22,2,15,57,0,86,213,TSTD2;thiosulfate sulfurtransferase (rhodanese)-like domain containing 2,-,-,-,-
158431,0,0,0,7,11,0,0,80,0,0,0,0,ZNF782;zinc finger protein 782,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
158434,0,0,0,0,0,0,36,0,1,0,0,0,LOC158434;uncharacterized LOC158434,-,-,-,-
158471,42,260,2,73,543,52,31,0,131,0,10,0,PRUNE2;prune homolog 2 (Drosophila),GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0006915//apoptotic process,GO:0016462//pyrophosphatase activity;GO:0046872//metal ion binding,K01514//Purine metabolism
1585,0,0,0,0,0,5,21,0,13,0,0,0,"CYP11B2;cytochrome P450, family 11, subfamily B, polypeptide 2",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0032342//aldosterone biosynthetic process;GO:0035865//cellular response to potassium ion;GO:0034651//cortisol biosynthetic process;GO:0055075//potassium ion homeostasis;GO:0003091//renal water homeostasis;GO:0016125//sterol metabolic process;GO:0055078//sodium ion homeostasis;GO:0032870//cellular response to hormone stimulus;GO:0006700//C21-steroid hormone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0002017//regulation of blood volume by renal aldosterone;GO:0006705//mineralocorticoid biosynthetic process;GO:0006805//xenobiotic metabolic process,GO:0047783//corticosterone 18-monooxygenase activity;GO:0005506//iron ion binding;GO:0004507//steroid 11-beta-monooxygenase activity;GO:0020037//heme binding,K07433//Steroid hormone biosynthesis;Metabolic pathways;K00497//Steroid hormone biosynthesis;Metabolic pathways
158506,0,0,0,0,0,0,0,0,2,0,0,0,ZNF645;zinc finger protein 645,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
158511,0,0,0,0,0,2,0,0,7,0,0,0,CSAG1;chondrosarcoma associated gene 1,-,-,-,-
158521,57,0,0,0,0,0,0,0,0,0,0,0,FMR1NB;fragile X mental retardation 1 neighbor,GO:0016021//integral component of membrane;GO:0005730//nucleolus,-,-,-
158572,0,0,0,0,0,34,0,0,33,0,0,0,USP27X-AS1;USP27X antisense RNA 1 (head to head),-,-,-,-
158584,0,0,0,0,1,38,17,0,18,0,0,0,FAAH2;fatty acid amide hydrolase 2,GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor;GO:0016787//hydrolase activity",K01426//Styrene degradation;Microbial metabolism in diverse environments;Arginine and proline metabolism;Aminobenzoate degradation;Tryptophan metabolism;Phenylalanine metabolism;Cyanoamino acid metabolism;K15528//Retrograde endocannabinoid signaling
158586,0,0,0,3,71,0,0,0,70,0,0,0,"ZXDB;zinc finger, X-linked, duplicated B",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
1586,0,0,39,0,15,33,0,56,0,0,0,0,"CYP17A1;cytochrome P450, family 17, subfamily A, polypeptide 1",GO:0030424//axon;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0005789//endoplasmic reticulum membrane,GO:0071371//cellular response to gonadotropin stimulus;GO:0030728//ovulation;GO:0055114//oxidation-reduction process;GO:0042448//progesterone metabolic process;GO:0009635//response to herbicide;GO:0034097//response to cytokine;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0018958//phenol-containing compound metabolic process;GO:0032526//response to retinoic acid;GO:0051591//response to cAMP;GO:0017085//response to insecticide;GO:0051597//response to methylmercury;GO:0018963//phthalate metabolic process;GO:0008202//steroid metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0030325//adrenal gland development;GO:0042493//response to drug;GO:0071236//cellular response to antibiotic;GO:0018879//biphenyl metabolic process;GO:0016125//sterol metabolic process;GO:0033327//Leydig cell differentiation;GO:0010212//response to ionizing radiation;GO:0010034//response to acetate;GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0031667//response to nutrient levels;GO:0048545//response to steroid hormone;GO:0060992//response to fungicide;GO:0007548//sex differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0006702//androgen biosynthetic process;GO:0042446//hormone biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0021766//hippocampus development;GO:0006805//xenobiotic metabolic process,GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0020037//heme binding;GO:0004508//steroid 17-alpha-monooxygenase activity;GO:0047442//17-alpha-hydroxyprogesterone aldolase activity,K00512//Steroid hormone biosynthesis;Metabolic pathways
1587,0,0,0,0,0,0,25,0,0,0,0,0,ADAM3A;ADAM metallopeptidase domain 3A (pseudogene),-,-,-,-
158724,0,0,0,0,0,0,0,0,24,0,0,0,"FAM47A;family with sequence similarity 47, member A",-,-,-,K13171//mRNA surveillance pathway;RNA transport;K09187//Lysine degradation
158747,0,0,0,0,15,27,21,0,2,231,0,0,MOSPD2;motile sperm domain containing 2,GO:0016020//membrane;GO:0016021//integral component of membrane,-,GO:0005198//structural molecule activity,K06096//Tight junction
158763,0,0,0,0,0,9,13,0,57,16,0,214,ARHGAP36;Rho GTPase activating protein 36,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K07526//Axon guidance
158787,74,0,0,0,0,30,0,0,57,0,4,0,RIBC1;RIB43A domain with coiled-coils 1,-,-,-,-
158798,0,0,0,0,0,17,0,0,0,0,0,0,AKAP14;A kinase (PRKA) anchor protein 14,GO:0005737//cytoplasm,GO:0007283//spermatogenesis,GO:0051018//protein kinase A binding,-
1588,0,0,0,0,0,0,0,0,51,0,0,0,"CYP19A1;cytochrome P450, family 19, subfamily A, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0016125//sterol metabolic process;GO:0006703//estrogen biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process;GO:0060736//prostate gland growth;GO:0008209//androgen metabolic process,"GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0070330//aromatase activity;GO:0005506//iron ion binding;GO:0009055//electron carrier activity;GO:0016712//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen",K07434//Steroid hormone biosynthesis;Metabolic pathways
158800,0,0,0,0,0,0,0,66,2,0,0,0,"RHOXF1;Rhox homeobox family, member 1",GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0019953//sexual reproduction;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007276//gamete generation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,-
158801,1,0,0,0,0,0,0,0,5,0,0,0,NKAPP1;NFKB activating protein pseudogene 1,-,-,-,-
158809,0,0,0,0,0,0,0,0,65,0,0,0,"MAGEB6;melanoma antigen family B, 6",-,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
158830,0,0,0,0,0,0,12,0,0,0,0,0,CXorf65;chromosome X open reading frame 65,-,-,-,K05070//Primary immunodeficiency;HTLV-I infection;Cytokine-cytokine receptor interaction;Endocytosis;Jak-STAT signaling pathway;Measles
158833,0,0,0,0,0,0,11,0,0,0,4,0,AWAT1;acyl-CoA wax alcohol acyltransferase 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006629//lipid metabolic process,GO:0047196//long-chain-alcohol O-fatty-acyltransferase activity,-
158835,0,0,0,0,0,0,0,0,24,0,16,0,AWAT2;acyl-CoA wax alcohol acyltransferase 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0010025//wax biosynthetic process;GO:0042572//retinol metabolic process,GO:0050252//retinol O-fatty-acyltransferase activity;GO:0047196//long-chain-alcohol O-fatty-acyltransferase activity,K11156//Vitamin digestion and absorption;Retinol metabolism
158866,0,0,0,0,14,0,58,1,20,0,1,0,"ZDHHC15;zinc finger, DHHC-type containing 15",GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,GO:0016188//synaptic vesicle maturation;GO:0045184//establishment of protein localization;GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K05766//Regulation of actin cytoskeleton;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
158880,0,50,0,21,13,0,0,0,46,0,3,0,USP51;ubiquitin specific peptidase 51,-,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0008270//zinc ion binding;GO:0004843//ubiquitin-specific protease activity,-
1589,0,0,0,0,0,0,0,0,17,0,0,0,"CYP21A2;cytochrome P450, family 21, subfamily A, polypeptide 2",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process;GO:0016125//sterol metabolic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0006704//glucocorticoid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0005496//steroid binding;GO:0004509//steroid 21-monooxygenase activity;GO:0020037//heme binding;GO:0008395//steroid hydroxylase activity;GO:0005506//iron ion binding,K00513//Steroid hormone biosynthesis;Metabolic pathways
158931,0,1,0,0,0,17,9,0,3,0,0,0,TCEAL6;transcription elongation factor A (SII)-like 6,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
158983,0,0,0,0,0,0,25,0,0,137,11,0,"H2BFWT;H2B histone family, member W, testis-specific",GO:0000786//nucleosome;GO:0031965//nuclear membrane,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Systemic lupus erythematosus;Alcoholism
159,0,1,0,18,81,1,0,0,29,0,4,0,ADSS;adenylosuccinate synthase,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006167//AMP biosynthetic process;GO:0002376//immune system process;GO:0060359//response to ammonium ion;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006531//aspartate metabolic process;GO:0044208//'de novo' AMP biosynthetic process;GO:0014074//response to purine-containing compound;GO:0006144//purine nucleobase metabolic process;GO:0071257//cellular response to electrical stimulus;GO:0006184//GTP catabolic process;GO:0046040//IMP metabolic process,GO:0005525//GTP binding;GO:0000287//magnesium ion binding;GO:0004019//adenylosuccinate synthase activity;GO:0042301//phosphate ion binding;GO:0005515//protein binding,"K01939//Chloroalkane and chloroalkene degradation;Purine metabolism;Other glycan degradation;Metabolic pathways;Chlorocyclohexane and chlorobenzene degradation;Microbial metabolism in diverse environments;Alanine, aspartate and glutamate metabolism"
159013,0,0,0,0,34,9,23,0,10,0,0,0,CXorf38;chromosome X open reading frame 38,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
159090,0,22,0,22,17,0,91,0,49,0,9,438,FAM122B;family with sequence similarity 122B,-,-,-,-
159091,0,96,160,67,125,1,0,50,9,0,312,0,FAM122C;family with sequence similarity 122C,-,-,-,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
1591,0,0,0,0,0,0,0,0,24,0,8,0,"CYP24A1;cytochrome P450, family 24, subfamily A, polypeptide 1",GO:0005743//mitochondrial inner membrane,GO:0008202//steroid metabolic process;GO:0042369//vitamin D catabolic process;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0070561//vitamin D receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0001649//osteoblast differentiation;GO:0042359//vitamin D metabolic process;GO:0033280//response to vitamin D,"GO:0020037//heme binding;GO:0008403//25-hydroxycholecalciferol-24-hydroxylase activity;GO:0016491//oxidoreductase activity;GO:0030342//1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity;GO:0005506//iron ion binding",K07436//Metabolic pathways;Steroid biosynthesis
159195,0,23,0,65,140,25,30,274,80,0,100,1,USP54;ubiquitin specific peptidase 54,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K14206//Protein digestion and absorption
1592,0,0,0,0,0,0,0,0,30,0,0,4,"CYP26A1;cytochrome P450, family 26, subfamily A, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0071300//cellular response to retinoic acid;GO:0014032//neural crest cell development;GO:0007417//central nervous system development;GO:0008152//metabolic process;GO:0034653//retinoic acid catabolic process;GO:0048384//retinoic acid receptor signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0005506//iron ion binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0020037//heme binding;GO:0001972//retinoic acid binding;GO:0019825//oxygen binding,K07437//Retinol metabolism
159296,0,0,0,0,0,0,0,70,4,0,4,0,NKX2-3;NK2 homeobox 3,GO:0005634//nucleus,"GO:0006641//triglyceride metabolic process;GO:0022612//gland morphogenesis;GO:0030225//macrophage differentiation;GO:0002317//plasma cell differentiation;GO:0001776//leukocyte homeostasis;GO:0048535//lymph node development;GO:0006351//transcription, DNA-templated;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0048536//spleen development;GO:0050900//leukocyte migration;GO:0042127//regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048541//Peyer's patch development",GO:0043565//sequence-specific DNA binding,-
1593,0,2,0,0,0,2,24,0,53,0,0,0,"CYP27A1;cytochrome P450, family 27, subfamily A, polypeptide 1",GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane,GO:0008203//cholesterol metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0016125//sterol metabolic process,GO:0005506//iron ion binding;GO:0030343//vitamin D3 25-hydroxylase activity;GO:0047749//cholestanetriol 26-monooxygenase activity;GO:0031073//cholesterol 26-hydroxylase activity;GO:0020037//heme binding;GO:0008395//steroid hydroxylase activity,K00488//PPAR signaling pathway;Metabolic pathways;Primary bile acid biosynthesis
159371,113,0,0,0,0,0,0,1,12,229,3,0,"SLC35G1;solute carrier family 35, member G1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:1990034//calcium ion export from cell;GO:0051480//cytosolic calcium ion homeostasis,GO:0005515//protein binding,-
1594,0,0,0,3,0,0,0,0,1,0,0,0,"CYP27B1;cytochrome P450, family 27, subfamily B, polypeptide 1",GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0043627//response to estrogen;GO:0046697//decidualization;GO:0034341//response to interferon-gamma;GO:0030282//bone mineralization;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:0055074//calcium ion homeostasis;GO:0033280//response to vitamin D;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0042369//vitamin D catabolic process;GO:0008202//steroid metabolic process;GO:0032496//response to lipopolysaccharide;GO:0006816//calcium ion transport;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0045618//positive regulation of keratinocyte differentiation;GO:0042359//vitamin D metabolic process;GO:0030500//regulation of bone mineralization;GO:0070314//G1 to G0 transition;GO:0044281//small molecule metabolic process;GO:0036378//calcitriol biosynthetic process from calciol;GO:0006805//xenobiotic metabolic process,GO:0004498//calcidiol 1-monooxygenase activity;GO:0020037//heme binding;GO:0005506//iron ion binding,K07438//Metabolic pathways;Steroid biosynthesis;Tuberculosis
1595,0,56,0,167,365,3,32,103,32,166,12,0,"CYP51A1;cytochrome P450, family 51, subfamily A, polypeptide 1",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0070988//demethylation;GO:0033488//cholesterol biosynthetic process via 24,25-dihydrolanosterol;GO:0016125//sterol metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006694//steroid biosynthetic process;GO:0044281//small molecule metabolic process",GO:0020037//heme binding;GO:0008398//sterol 14-demethylase activity;GO:0005506//iron ion binding,K05917//Biosynthesis of secondary metabolites;Steroid biosynthesis;Metabolic pathways
159686,0,0,0,0,0,43,93,0,7,0,11,0,CCDC147;coiled-coil domain containing 147,GO:0005615//extracellular space,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
159963,0,0,0,0,0,31,0,0,24,0,23,0,"SLC5A12;solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0016324//apical plasma membrane,GO:0055085//transmembrane transport;GO:0006814//sodium ion transport,GO:0015293//symporter activity,-
159989,0,0,0,0,19,0,0,0,39,0,0,0,CCDC67;coiled-coil domain containing 67,GO:0005737//cytoplasm;GO:0098536//deuterosome,GO:0098535//de novo centriole assembly;GO:0030030//cell projection organization,-,K12478//Phagosome;Endocytosis;Tuberculosis
16,0,4,1,21,63,27,3,4,33,0,18,0,AARS;alanyl-tRNA synthetase,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006457//protein folding;GO:0021680//cerebellar Purkinje cell layer development;GO:0043200//response to amino acid;GO:0006418//tRNA aminoacylation for protein translation;GO:0008033//tRNA processing;GO:0010467//gene expression;GO:0050885//neuromuscular process controlling balance;GO:0043524//negative regulation of neuron apoptotic process;GO:0006450//regulation of translational fidelity;GO:0001942//hair follicle development;GO:0008219//cell death;GO:0006400//tRNA modification;GO:0006419//alanyl-tRNA aminoacylation;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0004813//alanine-tRNA ligase activity;GO:0008270//zinc ion binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0016597//amino acid binding;GO:0000049//tRNA binding;GO:0005524//ATP binding,K01872//Microbial metabolism in diverse environments;Aminoacyl-tRNA biosynthesis;Purine metabolism
160,0,22,3,5,29,26,26,118,9,187,61,0,"AP2A1;adaptor-related protein complex 2, alpha 1 subunit",GO:0016324//apical plasma membrane;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0030122//AP-2 adaptor complex;GO:0030666//endocytic vesicle membrane;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006897//endocytosis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007411//axon guidance;GO:1900126//negative regulation of hyaluronan biosynthetic process;GO:0050690//regulation of defense response to virus by virus;GO:0007268//synaptic transmission;GO:0006895//Golgi to endosome transport;GO:0016032//viral process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006886//intracellular protein transport,GO:0008565//protein transporter activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,K11824//Endocytosis;Huntington's disease;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
1600,0,0,0,0,0,0,0,26,77,0,9,0,"DAB1;Dab, reelin signal transducer, homolog 1 (Drosophila)",GO:0005829//cytosol;GO:0005903//brush border;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0043005//neuron projection;GO:0014069//postsynaptic density;GO:0045177//apical part of cell;GO:0043025//neuronal cell body,GO:0097477//lateral motor column neuron migration;GO:0021517//ventral spinal cord development;GO:0048712//negative regulation of astrocyte differentiation;GO:0021589//cerebellum structural organization;GO:0016358//dendrite development;GO:0045666//positive regulation of neuron differentiation;GO:0045860//positive regulation of protein kinase activity;GO:0007162//negative regulation of cell adhesion;GO:0046426//negative regulation of JAK-STAT cascade;GO:0007264//small GTPase mediated signal transduction;GO:0042493//response to drug;GO:0007494//midgut development;GO:0021942//radial glia guided migration of Purkinje cell;GO:0050771//negative regulation of axonogenesis;GO:0007628//adult walking behavior;GO:0051645//Golgi localization;GO:0021813//cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration,GO:0043548//phosphatidylinositol 3-kinase binding,K12475//Endocytosis;K03998//Amoebiasis;Complement and coagulation cascades;Systemic lupus erythematosus;Prion diseases
160065,0,22,0,0,0,0,0,0,0,0,0,0,PATE1;prostate and testis expressed 1,GO:0005576//extracellular region,-,-,-
1601,0,0,0,8,0,0,2,1,28,0,0,0,"DAB2;Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)",GO:0070022//transforming growth factor beta receptor homodimeric complex;GO:0030132//clathrin coat of coated pit;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane;GO:0016324//apical plasma membrane;GO:0005765//lysosomal membrane;GO:0030136//clathrin-coated vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0007229//integrin-mediated signaling pathway;GO:0007257//activation of JUN kinase activity;GO:0006898//receptor-mediated endocytosis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0061024//membrane organization;GO:0001701//in utero embryonic development;GO:0035026//leading edge cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0007588//excretion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0007492//endoderm development;GO:0030335//positive regulation of cell migration;GO:0015031//protein transport;GO:0016055//Wnt signaling pathway;GO:0030099//myeloid cell differentiation;GO:2000643//positive regulation of early endosome to late endosome transport;GO:0001921//positive regulation of receptor recycling;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045807//positive regulation of endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0006907//pinocytosis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008283//cell proliferation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000370//positive regulation of clathrin-mediated endocytosis;GO:0048268//clathrin coat assembly;GO:0043066//negative regulation of apoptotic process;GO:0032091//negative regulation of protein binding","GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035615//clathrin adaptor activity;GO:0008022//protein C-terminus binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding;GO:0046332//SMAD binding;GO:0038024//cargo receptor activity",K12475//Endocytosis
160140,0,0,0,0,0,0,0,46,3,0,0,0,C11orf65;chromosome 11 open reading frame 65,-,-,-,-
1602,0,0,0,12,56,54,0,0,53,0,0,0,DACH1;dachshund family transcription factor 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0001967//suckling behavior;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly;GO:0007585//respiratory gaseous exchange;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0048147//negative regulation of fibroblast proliferation;GO:0030336//negative regulation of cell migration;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046545//development of primary female sexual characteristics;GO:0008283//cell proliferation,GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0005515//protein binding;GO:0003677//DNA binding,-
160287,0,0,0,0,3,10,17,0,19,0,0,0,LDHAL6A;lactate dehydrogenase A-like 6A,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process;GO:0044262//cellular carbohydrate metabolic process;GO:0006096//glycolytic process,GO:0004459//L-lactate dehydrogenase activity,K00016//Cysteine and methionine metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Metabolic pathways;Propanoate metabolism;Microbial metabolism in diverse environments;Pyruvate metabolism
160298,0,0,0,0,1,22,0,0,5,0,0,0,C11orf42;chromosome 11 open reading frame 42,-,-,-,-
1603,0,0,0,2,0,0,0,0,0,0,0,0,DAD1;defender against cell death 1,GO:0005789//endoplasmic reticulum membrane;GO:0008250//oligosaccharyltransferase complex;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0044267//cellular protein metabolic process;GO:0001824//blastocyst development;GO:0043066//negative regulation of apoptotic process;GO:0007584//response to nutrient;GO:0006915//apoptotic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006486//protein glycosylation;GO:0042493//response to drug;GO:0043687//post-translational protein modification,GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity,K12668//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
160335,0,0,1,0,20,1,0,53,27,0,0,0,TMTC2;transmembrane and tetratricopeptide repeat containing 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0055074//calcium ion homeostasis,GO:0005515//protein binding,K01886//Metabolic pathways;ABC transporters;Aminoacyl-tRNA biosynthesis;Ribosome;K09667//Other types of O-glycan biosynthesis
160365,0,0,0,0,0,1,0,0,0,0,0,0,CLECL1;C-type lectin-like 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,GO:0030246//carbohydrate binding,K06541//Graft-versus-host disease;Natural killer cell mediated cytotoxicity;Antigen processing and presentation
160418,0,0,0,0,0,0,60,0,29,0,7,0,TMTC3;transmembrane and tetratricopeptide repeat containing 3,GO:0016021//integral component of membrane,GO:0060447//bud outgrowth involved in lung branching;GO:0048747//muscle fiber development;GO:0010468//regulation of gene expression;GO:0048286//lung alveolus development;GO:0009791//post-embryonic development,-,K09667//Other types of O-glycan biosynthesis
160419,0,0,0,0,0,0,0,0,16,0,0,0,C12orf50;chromosome 12 open reading frame 50,-,-,-,-
160428,36,0,0,0,0,34,65,0,69,10,14,430,"ALDH1L2;aldehyde dehydrogenase 1 family, member L2",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0006730//one-carbon metabolic process;GO:0009258//10-formyltetrahydrofolate catabolic process;GO:0055114//oxidation-reduction process;GO:0032259//methylation;GO:0009058//biosynthetic process,"GO:0016155//formyltetrahydrofolate dehydrogenase activity;GO:0016620//oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0008168//methyltransferase activity;GO:0016742//hydroxymethyl-, formyl- and related transferase activity",K00289//One carbon pool by folate
160492,73,0,0,0,0,16,17,2,26,1,5,572,LMNTD1;lamin tail domain containing 1,GO:0005882//intermediate filament;GO:0005635//nuclear envelope;GO:0005737//cytoplasm,GO:0008283//cell proliferation,GO:0005198//structural molecule activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
1605,0,1,67,12,0,12,0,52,61,0,0,0,DAG1;dystroglycan 1 (dystrophin-associated glycoprotein 1),GO:0033268//node of Ranvier;GO:0005913//cell-cell adherens junction;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0043034//costamere;GO:0045121//membrane raft;GO:0070938//contractile ring;GO:0042383//sarcolemma;GO:0005604//basement membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0009279//cell outer membrane;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0016011//dystroglycan complex;GO:0005576//extracellular region;GO:0030175//filopodium;GO:0016010//dystrophin-associated glycoprotein complex;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space,GO:0006607//NLS-bearing protein import into nucleus;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0030198//extracellular matrix organization;GO:0030336//negative regulation of cell migration;GO:0022011//myelination in peripheral nervous system;GO:0002011//morphogenesis of an epithelial sheet;GO:0009615//response to virus;GO:0006509//membrane protein ectodomain proteolysis;GO:0019048//modulation by virus of host morphology or physiology;GO:0060445//branching involved in salivary gland morphogenesis;GO:0034453//microtubule anchoring;GO:0043409//negative regulation of MAPK cascade;GO:0021682//nerve maturation;GO:0051898//negative regulation of protein kinase B signaling;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0071711//basement membrane organization;GO:0043434//response to peptide hormone;GO:0071679//commissural neuron axon guidance;GO:0016340//calcium-dependent cell-matrix adhesion,GO:0051393//alpha-actinin binding;GO:0005515//protein binding;GO:0043237//laminin-1 binding;GO:0005509//calcium ion binding;GO:0015631//tubulin binding;GO:0042169//SH2 domain binding;GO:0001618//virus receptor activity;GO:0002162//dystroglycan binding;GO:0003779//actin binding;GO:0008307//structural constituent of muscle;GO:0032403//protein complex binding;GO:0017166//vinculin binding,K06265//ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Viral myocarditis;Dilated cardiomyopathy
160518,37,0,0,0,19,0,17,0,62,0,0,0,DENND5B;DENN/MADD domain containing 5B,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0050982//detection of mechanical stimulus;GO:0032851//positive regulation of Rab GTPase activity,GO:0005262//calcium channel activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K12861//Spliceosome
1606,0,4,0,12,1,8,78,59,29,0,3,0,"DGKA;diacylglycerol kinase, alpha 80kDa",GO:0005829//cytosol;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction,GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0005524//ATP binding,K00901//Glycerophospholipid metabolism;Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways
160622,108,0,31,0,0,0,0,0,0,0,15,0,GRASP;GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein,GO:0048471//perinuclear region of cytoplasm;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0008104//protein localization;GO:0007165//signal transduction,GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0030306//ADP-ribosylation factor binding,K13358//Aldosterone-regulated sodium reabsorption
1607,29,0,0,0,0,12,17,77,81,156,0,0,"DGKB;diacylglycerol kinase, beta 90kDa",GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0016310//phosphorylation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0035556//intracellular signal transduction,GO:0005509//calcium ion binding;GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding,K00901//Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways;Glycerophospholipid metabolism
160728,0,119,0,34,32,19,0,0,42,0,124,0,"SLC5A8;solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0006915//apoptotic process;GO:0006811//ion transport,GO:0015293//symporter activity,-
160760,0,11,0,14,3,0,0,0,37,0,0,0,PPTC7;PTC7 protein phosphatase homolog (S. cerevisiae),GO:0005739//mitochondrion,GO:0016311//dephosphorylation,GO:0004721//phosphoprotein phosphatase activity;GO:0046872//metal ion binding,-
160762,76,0,0,0,0,0,0,0,0,80,0,0,CCDC63;coiled-coil domain containing 63,-,-,-,K14000//Protein processing in endoplasmic reticulum;K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
160777,77,0,0,0,1,7,35,0,25,0,0,0,CCDC60;coiled-coil domain containing 60,-,-,-,-
1608,0,0,0,0,0,57,21,0,63,0,0,0,"DGKG;diacylglycerol kinase, gamma 90kDa",GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane,GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0007596//blood coagulation;GO:0048666//neuron development;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0030168//platelet activation,GO:0005524//ATP binding;GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0005509//calcium ion binding,K00901//Glycerophospholipid metabolism;Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways
160851,153,0,4,0,16,54,36,0,170,61,2,0,"DGKH;diacylglycerol kinase, eta",GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane,GO:0035556//intracellular signal transduction;GO:0030168//platelet activation;GO:0016310//phosphorylation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007596//blood coagulation;GO:0051259//protein oligomerization,GO:0005524//ATP binding;GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding,K00901//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism;Phosphatidylinositol signaling system
160857,15,0,0,4,29,0,0,83,0,0,0,0,CCDC122;coiled-coil domain containing 122,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
160897,0,0,0,0,17,25,0,0,38,0,0,0,GPR180;G protein-coupled receptor 180,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0019236//response to pheromone,-,-
1609,0,0,0,0,0,1,16,0,33,1,0,0,"DGKQ;diacylglycerol kinase, theta 110kDa",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0019933//cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0070528//protein kinase C signaling;GO:0007596//blood coagulation;GO:0070493//thrombin receptor signaling pathway;GO:0030168//platelet activation;GO:0033198//response to ATP;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation,GO:0019900//kinase binding;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043274//phospholipase binding;GO:0005524//ATP binding;GO:0003951//NAD+ kinase activity;GO:0033613//activating transcription factor binding,K00901//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism;Phosphatidylinositol signaling system
161,136,5,1,1,1,12,79,0,14,0,12,0,"AP2A2;adaptor-related protein complex 2, alpha 2 subunit",GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005905//coated pit;GO:0030131//clathrin adaptor complex;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005829//cytosol,GO:0050690//regulation of defense response to virus by virus;GO:0007268//synaptic transmission;GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006897//endocytosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006886//intracellular protein transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016032//viral process,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008565//protein transporter activity,K11824//Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle;Endocytosis;Huntington's disease
1610,0,0,0,0,0,20,0,0,29,141,0,439,DAO;D-amino-acid oxidase,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0005778//peroxisomal membrane;GO:0005741//mitochondrial outer membrane,GO:0006551//leucine metabolic process;GO:0006562//proline catabolic process;GO:0042416//dopamine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0055130//D-alanine catabolic process;GO:0055114//oxidation-reduction process;GO:0034641//cellular nitrogen compound metabolic process;GO:0046487//glyoxylate metabolic process;GO:0036088//D-serine catabolic process,GO:0048037//cofactor binding;GO:0005515//protein binding;GO:0071949//FAD binding;GO:0046983//protein dimerization activity;GO:0005102//receptor binding;GO:0003884//D-amino-acid oxidase activity,"K00273//Metabolic pathways;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Peroxisome;Glycine, serine and threonine metabolism;Penicillin and cephalosporin biosynthesis"
161003,0,0,0,0,0,0,56,115,16,0,0,0,STOML3;stomatin (EPB72)-like 3,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005929//cilium;GO:0045121//membrane raft,GO:0007165//signal transduction,-,K03364//Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Cell cycle
1611,0,3,5,32,96,0,0,0,0,0,2,0,DAP;death-associated protein,-,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0034198//cellular response to amino acid starvation;GO:0010507//negative regulation of autophagy;GO:0097190//apoptotic signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity",GO:0070513//death domain binding,-
161142,0,0,0,0,0,0,0,0,0,0,8,0,"FAM71D;family with sequence similarity 71, member D",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,-,-,-
161145,43,0,0,0,0,0,0,54,6,0,0,0,TMEM229B;transmembrane protein 229B,GO:0016021//integral component of membrane,-,-,-
161159,0,0,0,0,0,0,0,0,6,0,0,0,ACTN1-AS1;ACTN1 antisense RNA 1,-,-,-,-
161176,0,0,0,0,0,32,5,41,0,213,19,0,"SYNE3;spectrin repeat containing, nuclear envelope family member 3",GO:0005640//nuclear outer membrane;GO:0005635//nuclear envelope;GO:0034993//SUN-KASH complex;GO:0005791//rough endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0008360//regulation of cell shape;GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0007010//cytoskeleton organization;GO:0090150//establishment of protein localization to membrane,GO:0051015//actin filament binding;GO:0005515//protein binding,-
161198,159,0,0,0,0,0,19,63,7,0,0,0,"CLEC14A;C-type lectin domain family 14, member A",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
1612,0,0,0,9,8,26,0,0,111,22,18,0,DAPK1;death-associated protein kinase 1,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process;GO:0010506//regulation of autophagy;GO:0017148//negative regulation of translation;GO:0046777//protein autophosphorylation;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0071346//cellular response to interferon-gamma;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0042981//regulation of apoptotic process,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding,K08803//Bladder cancer;Pathways in cancer
161247,0,0,0,0,0,0,0,0,23,0,0,0,FITM1;fat storage-inducing transmembrane protein 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0034389//lipid particle organization;GO:0010890//positive regulation of sequestering of triglyceride,-,-
161253,30,0,0,0,0,0,0,49,0,1,0,0,REM2;RAS (RAD and GEM)-like GTP binding 2,GO:0005886//plasma membrane,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
161291,4,0,0,10,10,16,0,53,16,0,0,0,TMEM30B;transmembrane protein 30B,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0006869//lipid transport,GO:0005515//protein binding,-
1613,90,0,0,0,0,0,80,46,47,0,11,0,DAPK3;death-associated protein kinase 3,"GO:0016605//PML body;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center","GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0030182//neuron differentiation;GO:0006915//apoptotic process;GO:0051893//regulation of focal adhesion assembly;GO:0017148//negative regulation of translation;GO:2000145//regulation of cell motility;GO:0046777//protein autophosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0016568//chromatin modification;GO:0071346//cellular response to interferon-gamma;GO:0042981//regulation of apoptotic process;GO:0000910//cytokinesis;GO:0035556//intracellular signal transduction;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0010506//regulation of autophagy;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0006355//regulation of transcription, DNA-templated;GO:0006940//regulation of smooth muscle contraction;GO:0007088//regulation of mitosis",GO:0004674//protein serine/threonine kinase activity;GO:0017048//Rho GTPase binding;GO:0043522//leucine zipper domain binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity,K08803//Bladder cancer;Pathways in cancer
161357,0,0,0,0,0,18,2,0,46,0,0,1,MDGA2;MAM domain containing glycosylphosphatidylinositol anchor 2,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0007389//pattern specification process;GO:0021522//spinal cord motor neuron differentiation,-,K06756//Cell adhesion molecules (CAMs);K06491//Cell adhesion molecules (CAMs);Prion diseases
161394,0,0,0,0,0,0,5,0,43,0,0,0,SAMD15;sterile alpha motif domain containing 15,-,-,-,K00901//Glycerophospholipid metabolism;Phosphatidylinositol signaling system;Glycerolipid metabolism;Metabolic pathways;K14721//Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism;Cytosolic DNA-sensing pathway
161424,0,171,153,247,273,0,99,236,120,0,235,0,NOP9;NOP9 nucleolar protein,-,-,GO:0044822//poly(A) RNA binding,-
161436,0,69,1,38,310,2,47,2,47,62,10,350,EML5;echinoderm microtubule associated protein like 5,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
161497,2,0,0,0,0,0,36,0,89,0,22,0,STRC;stereocilin,GO:0032426//stereocilium bundle tip;GO:0032420//stereocilium;GO:0060091//kinocilium;GO:0009986//cell surface,GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060088//auditory receptor cell stereocilium organization,-,-
1615,0,26,2,23,89,0,7,0,14,0,0,0,DARS;aspartyl-tRNA synthetase,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression;GO:0006461//protein complex assembly;GO:0006412//translation;GO:0006422//aspartyl-tRNA aminoacylation,GO:0004046//aminoacylase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004815//aspartate-tRNA ligase activity,K01876//Aminoacyl-tRNA biosynthesis
161514,0,0,0,0,0,0,0,0,14,0,10,0,"TBC1D21;TBC1 domain family, member 21",GO:0070062//extracellular vesicular exosome;GO:0001669//acrosomal vesicle,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0017137//Rab GTPase binding;GO:0003779//actin binding;GO:0005097//Rab GTPase activator activity,K13136//RNA transport
161582,0,0,0,0,0,20,0,0,8,99,0,0,DYX1C1;dyslexia susceptibility 1 candidate 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane,GO:0061136//regulation of proteasomal protein catabolic process;GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0001764//neuron migration;GO:0003341//cilium movement;GO:0007368//determination of left/right symmetry;GO:0033146//regulation of intracellular estrogen receptor signaling pathway,GO:0005515//protein binding;GO:0030331//estrogen receptor binding,K09553//Prion diseases
1616,0,0,0,0,2,0,0,0,0,0,0,0,DAXX;death-domain associated protein,"GO:0005737//cytoplasm;GO:0070603//SWI/SNF superfamily-type complex;GO:0005634//nucleus;GO:0000792//heterochromatin;GO:0000775//chromosome, centromeric region;GO:0016605//PML body;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0000281//mitotic cytokinesis;GO:0006334//nucleosome assembly;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0031396//regulation of protein ubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:1901216//positive regulation of neuron death;GO:0030521//androgen receptor signaling pathway;GO:0016032//viral process;GO:0045860//positive regulation of protein kinase activity;GO:0006338//chromatin remodeling;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007257//activation of JUN kinase activity;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation",GO:0030295//protein kinase activator activity;GO:0042393//histone binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0047485//protein N-terminus binding;GO:0003714//transcription corepressor activity;GO:0019901//protein kinase binding;GO:0050681//androgen receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0005057//receptor signaling protein activity;GO:0002039//p53 binding,K02308//Amyotrophic lateral sclerosis (ALS);Herpes simplex infection;MAPK signaling pathway
161725,0,0,2,0,0,20,0,153,89,0,8,0,OTUD7A;OTU deubiquitinase 7A,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0035871//protein K11-linked deubiquitination;GO:0006508//proteolysis,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0004843//ubiquitin-specific protease activity,-
161742,0,0,0,0,3,1,12,0,14,0,2,0,"SPRED1;sprouty-related, EVH1 domain containing 1",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005901//caveola;GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0090311//regulation of protein deacetylation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0000188//inactivation of MAPK activity;GO:0010923//negative regulation of phosphatase activity",GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019902//phosphatase binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0005173//stem cell factor receptor binding,K04703//Jak-STAT signaling pathway
161753,0,0,0,0,0,0,0,0,11,0,0,0,ODF3L1;outer dense fiber of sperm tails 3-like 1,-,-,-,-
161779,0,0,0,0,0,26,0,0,0,0,0,0,PGBD4;piggyBac transposable element derived 4,-,-,-,K00844//Galactose metabolism;Metabolic pathways;Fructose and mannose metabolism;Type II diabetes mellitus;Streptomycin biosynthesis;Microbial metabolism in diverse environments;Insulin signaling pathway;Carbohydrate digestion and absorption;Starch and sucrose metabolism;Biosynthesis of secondary metabolites;Butirosin and neomycin biosynthesis;Amino sugar and nucleotide sugar metabolism;Glycolysis / Gluconeogenesis
1618,0,0,0,0,12,14,0,0,37,0,9,0,DAZL;deleted in azoospermia-like,GO:0005844//polysome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0045836//positive regulation of meiosis;GO:0007281//germ cell development;GO:0001556//oocyte maturation;GO:0045948//positive regulation of translational initiation,GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0003730//mRNA 3'-UTR binding;GO:0008494//translation activator activity;GO:0003723//RNA binding,K14411//mRNA surveillance pathway;K13126//RNA transport;mRNA surveillance pathway;RNA degradation
161823,0,23,8,28,70,0,13,0,46,0,42,0,ADAL;adenosine deaminase-like,GO:0005829//cytosol,GO:0006144//purine nucleobase metabolic process;GO:0046103//inosine biosynthetic process;GO:0006154//adenosine catabolic process;GO:0017144//drug metabolic process;GO:0044281//small molecule metabolic process;GO:0009117//nucleotide metabolic process;GO:0043103//hypoxanthine salvage;GO:0043101//purine-containing compound salvage,GO:0004000//adenosine deaminase activity;GO:0046872//metal ion binding,K01488//Metabolic pathways;Primary immunodeficiency;Purine metabolism;K01500//Atrazine degradation;Microbial metabolism in diverse environments
161829,0,0,0,0,0,0,12,0,0,0,0,0,EXD1;exonuclease 3'-5' domain containing 1,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0008408//3'-5' exonuclease activity;GO:0003676//nucleic acid binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
161835,0,0,0,0,0,0,0,0,100,0,7,0,FSIP1;fibrous sheath interacting protein 1,-,-,-,-
161882,0,0,0,0,0,9,32,3,71,0,6,0,"ZFPM1;zinc finger protein, FOG family member 1",GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0017053//transcriptional repressor complex,"GO:0071733//transcriptional activation by promoter-enhancer looping;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0002295//T-helper cell lineage commitment;GO:0055008//cardiac muscle tissue morphogenesis;GO:0007596//blood coagulation;GO:0035162//embryonic hemopoiesis;GO:0045403//negative regulation of interleukin-4 biosynthetic process;GO:0003195//tricuspid valve formation;GO:0030220//platelet formation;GO:0003181//atrioventricular valve morphogenesis;GO:0060318//definitive erythrocyte differentiation;GO:0003151//outflow tract morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0003192//mitral valve formation;GO:0035855//megakaryocyte development;GO:0030851//granulocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060319//primitive erythrocyte differentiation;GO:0032642//regulation of chemokine production;GO:0045599//negative regulation of fat cell differentiation;GO:0032091//negative regulation of protein binding;GO:0006351//transcription, DNA-templated;GO:0030219//megakaryocyte differentiation;GO:0060413//atrial septum morphogenesis;GO:0030218//erythrocyte differentiation;GO:0060377//negative regulation of mast cell differentiation;GO:0045078//positive regulation of interferon-gamma biosynthetic process",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0008134//transcription factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
161931,0,0,0,0,0,24,0,0,3,0,0,0,ADAD2;adenosine deaminase domain containing 2,-,GO:0006396//RNA processing,GO:0003723//RNA binding;GO:0004000//adenosine deaminase activity,K12968//Cytosolic DNA-sensing pathway;Influenza A;Measles
162,0,23,1,12,69,61,0,37,25,197,0,110,"AP1B1;adaptor-related protein complex 1, beta 1 subunit",GO:0005829//cytosol;GO:0030659//cytoplasmic vesicle membrane;GO:0000139//Golgi membrane;GO:0032588//trans-Golgi network membrane;GO:0030131//clathrin adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0005765//lysosomal membrane,GO:0050690//regulation of defense response to virus by virus;GO:0061024//membrane organization;GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0016032//viral process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0005215//transporter activity;GO:0008565//protein transporter activity;GO:0019901//protein kinase binding;GO:0005515//protein binding,K12392//Lysosome
1620,0,1,0,12,0,11,0,0,25,0,0,0,BRINP1;bone morphogenetic protein/retinoic acid inducible neural-specific 1,GO:0005737//cytoplasm,GO:0071300//cellular response to retinoic acid;GO:0045786//negative regulation of cell cycle;GO:0008219//cell death;GO:0045930//negative regulation of mitotic cell cycle;GO:0045666//positive regulation of neuron differentiation;GO:0007050//cell cycle arrest,GO:0005515//protein binding,-
162073,0,0,0,0,70,1,4,91,5,0,2,0,"ITPRIPL2;inositol 1,4,5-trisphosphate receptor interacting protein-like 2",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
1621,100,0,0,0,0,0,13,0,31,1,14,429,DBH;dopamine beta-hydroxylase (dopamine beta-monooxygenase),GO:0034466//chromaffin granule lumen;GO:0034774//secretory granule lumen;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005576//extracellular region;GO:0030658//transport vesicle membrane;GO:0042584//chromaffin granule membrane;GO:0005737//cytoplasm,GO:0042423//catecholamine biosynthetic process;GO:0050900//leukocyte migration;GO:0007613//memory;GO:0042127//regulation of cell proliferation;GO:0001975//response to amphetamine;GO:0008542//visual learning;GO:0045907//positive regulation of vasoconstriction;GO:0034641//cellular nitrogen compound metabolic process;GO:0042421//norepinephrine biosynthetic process;GO:0048265//response to pain;GO:0007268//synaptic transmission;GO:0042420//dopamine catabolic process;GO:0001816//cytokine production;GO:0055114//oxidation-reduction process;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:0044281//small molecule metabolic process;GO:0001974//blood vessel remodeling;GO:0007626//locomotory behavior;GO:0042593//glucose homeostasis;GO:0042711//maternal behavior;GO:0042596//fear response;GO:0048149//behavioral response to ethanol;GO:0002443//leukocyte mediated immunity;GO:0042309//homoiothermy,GO:0005507//copper ion binding;GO:0031418//L-ascorbic acid binding;GO:0003824//catalytic activity;GO:0004500//dopamine beta-monooxygenase activity,K00503//Metabolic pathways;Tyrosine metabolism
1622,0,58,1,158,346,13,0,55,5,0,0,0,"DBI;diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)",GO:0097038//perinuclear endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion,GO:0006641//triglyceride metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0018345//protein palmitoylation;GO:0006810//transport;GO:0001942//hair follicle development,GO:0030156//benzodiazepine receptor binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding;GO:0036042//long-chain fatty acyl-CoA binding,K08762//PPAR signaling pathway
162239,0,0,0,8,24,16,0,0,24,118,0,0,ZFP1;ZFP1 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162282,53,0,0,0,0,18,0,0,0,0,2,0,ANKFN1;ankyrin-repeat and fibronectin type III domain containing 1,-,-,-,-
162333,77,0,0,7,18,0,0,0,32,11,16,0,"MARCH10;membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase",-,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
162387,30,0,0,0,0,0,25,0,0,0,0,0,MFSD6L;major facilitator superfamily domain containing 6-like,GO:0016021//integral component of membrane,-,-,-
162394,0,0,1,13,65,0,0,0,22,0,5,0,SLFN5;schlafen family member 5,GO:0005634//nucleus,GO:0030154//cell differentiation,GO:0005524//ATP binding,-
162417,68,0,0,0,0,0,0,0,12,0,12,0,NAGS;N-acetylglutamate synthase,GO:0005759//mitochondrial matrix,GO:0000050//urea cycle;GO:0006526//arginine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006536//glutamate metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0004042//acetyl-CoA:L-glutamate N-acetyltransferase activity,K11067//Arginine and proline metabolism;Metabolic pathways
162427,0,0,0,0,1,19,30,83,28,0,3,0,"FAM134C;family with sequence similarity 134, member C",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
162461,16,0,0,0,0,0,0,0,49,57,6,0,TMEM92;transmembrane protein 92,GO:0016021//integral component of membrane,-,-,-
162466,0,0,2,0,4,22,0,0,1,163,0,1,"PHOSPHO1;phosphatase, orphan 1",GO:0005829//cytosol,GO:0001958//endochondral ossification;GO:0006644//phospholipid metabolic process;GO:0035630//bone mineralization involved in bone maturation;GO:0046474//glycerophospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030500//regulation of bone mineralization;GO:0016311//dephosphorylation;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006646//phosphatidylethanolamine biosynthetic process,GO:0052731//phosphocholine phosphatase activity;GO:0046872//metal ion binding;GO:0052732//phosphoethanolamine phosphatase activity;GO:0016462//pyrophosphatase activity,K06124//Metabolic pathways;Glycerophospholipid metabolism
162494,0,0,0,0,0,0,36,0,15,0,12,0,"RHBDL3;rhomboid, veinlet-like 3 (Drosophila)",GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K02857//Dorso-ventral axis formation
162514,0,0,0,0,0,36,17,53,43,0,13,0,"TRPV3;transient receptor potential cation channel, subfamily V, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex,GO:0090280//positive regulation of calcium ion import;GO:0042636//negative regulation of hair cycle;GO:0009408//response to heat;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport,GO:0005262//calcium channel activity,-
162515,0,0,0,0,0,7,0,0,23,3,0,0,"SLC16A11;solute carrier family 16, member 11",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006629//lipid metabolic process;GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
162517,0,0,0,0,0,0,0,0,13,0,0,0,FBXO39;F-box protein 39,-,-,-,-
162540,0,1,0,0,0,0,48,0,1,0,0,0,SPPL2C;signal peptide peptidase like 2C,GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006509//membrane protein ectodomain proteolysis;GO:0031293//membrane protein intracellular domain proteolysis,GO:0004190//aspartic-type endopeptidase activity;GO:0042803//protein homodimerization activity,-
162605,0,0,0,0,0,0,0,0,21,0,0,326,KRT28;keratin 28,GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0005737//cytoplasm,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
162632,0,0,1,0,0,22,1,32,8,0,0,0,USP32P1;ubiquitin specific peptidase 32 pseudogene 1,-,-,-,-
162655,0,0,0,0,0,0,23,0,47,0,5,0,ZNF519;zinc finger protein 519,GO:0005634//nucleus,"GO:0007283//spermatogenesis;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162681,0,0,0,0,0,2,0,0,48,0,1,0,C18orf54;chromosome 18 open reading frame 54,GO:0005576//extracellular region,-,-,-
162699,0,0,0,0,1,0,0,0,0,0,0,0,TCEB3C;transcription elongation factor B polypeptide 3C (elongin A3),GO:0016021//integral component of membrane;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
1627,184,0,0,0,3,21,41,0,26,0,0,0,DBN1;drebrin 1,GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0005921//gap junction;GO:0042641//actomyosin,GO:0050773//regulation of dendrite development;GO:0061351//neural precursor cell proliferation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0032507//maintenance of protein location in cell;GO:0007015//actin filament organization;GO:0010644//cell communication by electrical coupling,GO:0003779//actin binding;GO:0005522//profilin binding;GO:0005515//protein binding,-
1628,0,0,0,0,0,12,0,0,13,0,6,0,DBP;D site of albumin promoter (albumin D-box) binding protein,GO:0005634//nucleus,"GO:0048511//rhythmic process;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001889//liver development",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
1629,0,57,0,58,205,12,0,0,50,0,0,0,DBT;dihydrolipoamide branched chain transacylase E2,GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005759//mitochondrial matrix;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex,GO:0009083//branched-chain amino acid catabolic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0043754//dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity,"K09699//Valine, leucine and isoleucine degradation;Metabolic pathways;Biosynthesis of secondary metabolites"
162962,0,0,0,12,1,0,25,0,4,0,0,0,ZNF836;zinc finger protein 836,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162963,79,0,0,0,0,0,0,0,0,0,0,154,ZNF610;zinc finger protein 610,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
162966,0,0,0,13,17,8,0,0,26,0,0,0,ZNF600;zinc finger protein 600,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
162967,0,0,24,0,9,0,0,43,91,0,0,0,ZNF320;zinc finger protein 320,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
162968,0,0,57,53,14,0,0,0,0,93,39,0,ZNF497;zinc finger protein 497,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
162972,0,29,0,21,39,0,1,1,18,0,23,0,ZNF550;zinc finger protein 550,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162979,0,0,0,0,0,0,24,35,17,0,0,0,ZNF296;zinc finger protein 296,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162989,0,0,0,0,8,10,0,0,5,0,0,0,DEDD2;death effector domain containing 2,GO:0005730//nucleolus,"GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0019725//cellular homeostasis;GO:0016075//rRNA catabolic process;GO:0006396//RNA processing;GO:0035556//intracellular signal transduction;GO:0006351//transcription, DNA-templated;GO:0030262//apoptotic nuclear changes;GO:0045892//negative regulation of transcription, DNA-templated",GO:0030159//receptor signaling complex scaffold activity;GO:0003677//DNA binding;GO:0005515//protein binding,-
162993,0,0,41,14,1,0,5,21,23,0,63,0,ZNF846;zinc finger protein 846,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
162998,0,0,0,0,0,66,1,0,0,0,0,0,"OR7D2;olfactory receptor, family 7, subfamily D, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,"GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0006355//regulation of transcription, DNA-templated;GO:0007186//G-protein coupled receptor signaling pathway",GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
163,0,53,2,82,315,42,34,0,77,0,0,0,"AP2B1;adaptor-related protein complex 2, beta 1 subunit",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005905//coated pit;GO:0030131//clathrin adaptor complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0030666//endocytic vesicle membrane;GO:0030669//clathrin-coated endocytic vesicle membrane,GO:0006886//intracellular protein transport;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007268//synaptic transmission;GO:0050690//regulation of defense response to virus by virus;GO:0007411//axon guidance;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006897//endocytosis,GO:0005515//protein binding;GO:0030276//clathrin binding;GO:0008565//protein transporter activity,K11825//Huntington's disease;Endocytosis;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
1630,95,0,0,0,0,22,25,0,70,0,11,0,DCC;DCC netrin 1 receptor,GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030424//axon;GO:0032584//growth cone membrane,GO:0001975//response to amphetamine;GO:0042981//regulation of apoptotic process;GO:0033563//dorsal/ventral axon guidance;GO:0021965//spinal cord ventral commissure morphogenesis;GO:0010976//positive regulation of neuron projection development;GO:2000171//negative regulation of dendrite development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006915//apoptotic process;GO:0001764//neuron migration;GO:0033564//anterior/posterior axon guidance;GO:2001141//regulation of RNA biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0010977//negative regulation of neuron projection development;GO:0007409//axonogenesis;GO:0007411//axon guidance;GO:0038007//netrin-activated signaling pathway;GO:0048671//negative regulation of collateral sprouting,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0005042//netrin receptor activity;GO:0042802//identical protein binding;GO:0003713//transcription coactivator activity,K06765//Colorectal cancer;Pathways in cancer;Axon guidance
163033,0,0,0,0,0,0,0,0,0,0,1,0,ZNF579;zinc finger protein 579,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
163049,0,0,0,13,36,0,21,0,9,0,0,0,ZNF791;zinc finger protein 791,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
163050,44,1,0,14,25,0,0,0,15,0,0,0,ZNF564;zinc finger protein 564,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
163051,0,0,1,11,41,16,38,46,24,0,0,348,ZNF709;zinc finger protein 709,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
163059,0,0,0,0,26,0,18,0,32,0,15,0,ZNF433;zinc finger protein 433,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
163081,0,0,0,0,0,4,0,0,0,0,0,0,ZNF567;zinc finger protein 567,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
163087,0,0,0,0,63,0,0,0,1,0,0,0,ZNF383;zinc finger protein 383,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
163115,0,0,0,0,16,0,0,0,3,0,0,0,ZNF781;zinc finger protein 781,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
163126,0,19,0,9,0,0,18,0,9,0,0,0,EID2;EP300 interacting inhibitor of differentiation 2,GO:0005634//nucleus;GO:0005622//intracellular;GO:0005730//nucleolus,"GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0042127//regulation of cell proliferation;GO:0030154//cell differentiation;GO:0007183//SMAD protein complex assembly",GO:0046332//SMAD binding;GO:0005515//protein binding,-
163131,0,0,0,31,50,0,4,47,6,0,9,0,ZNF780B;zinc finger protein 780B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
163154,0,0,0,0,0,14,0,0,12,0,0,0,PRR22;proline rich 22,-,-,-,-
163175,83,33,0,8,0,0,0,0,28,1,5,0,"LGI4;leucine-rich repeat LGI family, member 4",GO:0005615//extracellular space,GO:0022011//myelination in peripheral nervous system;GO:0042551//neuron maturation;GO:0014009//glial cell proliferation;GO:0008344//adult locomotory behavior,-,K06839//Axon guidance
163183,0,0,0,0,0,0,0,51,0,0,0,0,"SYNE4;spectrin repeat containing, nuclear envelope family member 4",GO:0031309//integral component of nuclear outer membrane,GO:0045198//establishment of epithelial cell apical/basal polarity,GO:0003779//actin binding,-
1632,0,2,1,12,11,0,60,0,0,0,0,0,ECI1;enoyl-CoA delta isomerase 1,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0044255//cellular lipid metabolic process,GO:0004165//dodecenoyl-CoA delta-isomerase activity,K13238//Fatty acid metabolism
163223,0,0,0,0,0,25,0,0,0,0,0,0,ZNF676;zinc finger protein 676,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
163227,0,0,0,0,11,30,43,0,79,0,0,0,ZNF100;zinc finger protein 100,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
163255,0,0,0,0,0,0,41,0,0,0,0,0,ZNF540;zinc finger protein 540,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0017148//negative regulation of translation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000900//translation repressor activity, nucleic acid binding;GO:0003677//DNA binding",-
163259,1,0,2,0,13,1,0,69,75,0,63,0,DENND2C;DENN/MADD domain containing 2C,-,GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
1633,0,0,0,8,5,9,0,0,43,0,0,0,DCK;deoxycytidine kinase,GO:0005634//nucleus;GO:0005829//cytosol,GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0016310//phosphorylation;GO:0043101//purine-containing compound salvage;GO:0043097//pyrimidine nucleoside salvage;GO:0006144//purine nucleobase metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0042803//protein homodimerization activity;GO:0004137//deoxycytidine kinase activity;GO:0019206//nucleoside kinase activity;GO:0008144//drug binding;GO:0005524//ATP binding,K00893//Purine metabolism;Pyrimidine metabolism;Metabolic pathways
163351,8,0,0,0,0,31,0,0,31,0,11,657,"GBP6;guanylate binding protein family, member 6",GO:0070062//extracellular vesicular exosome,GO:0071346//cellular response to interferon-gamma;GO:0042742//defense response to bacterium;GO:0006184//GTP catabolic process;GO:0006955//immune response,GO:0003924//GTPase activity;GO:0005525//GTP binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
1634,0,0,0,0,0,27,0,38,11,0,0,0,DCN;decorin,GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0005578//proteinaceous extracellular matrix;GO:0005589//collagen type VI trimer;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0009612//response to mechanical stimulus;GO:0007519//skeletal muscle tissue development;GO:0030203//glycosaminoglycan metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0007568//aging;GO:0022617//extracellular matrix disassembly;GO:0030204//chondroitin sulfate metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0001890//placenta development;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0009887//organ morphogenesis;GO:0042060//wound healing;GO:0032496//response to lipopolysaccharide;GO:0044281//small molecule metabolic process;GO:0001822//kidney development;GO:0030198//extracellular matrix organization,GO:0050840//extracellular matrix binding;GO:0005539//glycosaminoglycan binding;GO:0005518//collagen binding;GO:0047485//protein N-terminus binding;GO:0044822//poly(A) RNA binding,K04660//TGF-beta signaling pathway
163404,0,0,0,0,0,24,0,0,14,0,0,0,LPPR5;lipid phosphate phosphatase-related protein type 5,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K01080//Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Sphingolipid metabolism;Ether lipid metabolism
163479,0,0,0,0,0,27,0,0,36,0,0,0,FNDC7;fibronectin type III domain containing 7,GO:0005576//extracellular region,-,-,K06252//ECM-receptor interaction;Focal adhesion;K05717//Focal adhesion;Amoebiasis;Small cell lung cancer;Pathways in cancer;Bacterial invasion of epithelial cells;ECM-receptor interaction;Regulation of actin cytoskeleton
163486,0,0,0,0,7,0,0,0,2,0,0,0,DENND1B;DENN/MADD domain containing 1B,GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle,GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome;K02896//Ribosome
1635,0,0,19,11,1,9,0,0,0,89,0,0,DCTD;dCMP deaminase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0009165//nucleotide biosynthetic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0008270//zinc ion binding;GO:0004132//dCMP deaminase activity,K01493//Pyrimidine metabolism;Purine metabolism;Metabolic pathways
163589,0,0,0,0,0,6,28,0,52,0,2,72,TDRD5;tudor domain containing 5,GO:0071546//pi-body;GO:0033391//chromatoid body,GO:0007286//spermatid development;GO:0043046//DNA methylation involved in gamete generation;GO:0030719//P granule organization,-,K15979//Epstein-Barr virus infection
163590,0,0,0,38,64,6,0,0,57,0,4,0,TOR1AIP2;torsin A interacting protein 2,GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0007029//endoplasmic reticulum organization;GO:0032781//positive regulation of ATPase activity,GO:0051117//ATPase binding;GO:0001671//ATPase activator activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
1636,81,1,26,0,0,48,59,23,68,0,0,1,ACE;angiotensin I converting enzyme,GO:0005576//extracellular region;GO:0005768//endosome;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0050482//arachidonic acid secretion;GO:0060218//hematopoietic stem cell differentiation;GO:0002005//angiotensin catabolic process in blood;GO:0014910//regulation of smooth muscle cell migration;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0042312//regulation of vasodilation;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0019229//regulation of vasoconstriction;GO:0008217//regulation of blood pressure;GO:0032943//mononuclear cell proliferation;GO:0001974//blood vessel remodeling;GO:0001822//kidney development;GO:0002019//regulation of renal output by angiotensin;GO:0042447//hormone catabolic process;GO:0043171//peptide catabolic process;GO:0002003//angiotensin maturation,GO:0004175//endopeptidase activity;GO:0004180//carboxypeptidase activity;GO:0008237//metallopeptidase activity;GO:0031404//chloride ion binding;GO:0008270//zinc ion binding;GO:0031711//bradykinin receptor binding;GO:0008241//peptidyl-dipeptidase activity;GO:0005515//protein binding;GO:0003779//actin binding;GO:0008144//drug binding,K01283//Renin-angiotensin system;Hypertrophic cardiomyopathy (HCM);Chagas disease (American trypanosomiasis)
163688,0,0,0,0,0,0,0,0,0,0,4,2,CALML6;calmodulin-like 6,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005509//calcium ion binding,K02183//Olfactory transduction;Calcium signaling pathway;Salivary secretion;Gastric acid secretion;Glioma;Melanogenesis;Neurotrophin signaling pathway;Alzheimer's disease;Alcoholism;Tuberculosis;Pertussis;Long-term potentiation;GnRH signaling pathway;Phosphatidylinositol signaling system;Dopaminergic synapse;Insulin signaling pathway;Phototransduction;Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Vascular smooth muscle contraction;Oocyte meiosis
163702,130,0,0,0,4,0,0,48,1,0,11,0,"IFNLR1;interferon, lambda receptor 1",GO:0016021//integral component of membrane;GO:0032002//interleukin-28 receptor complex,GO:0034342//response to type III interferon;GO:0051607//defense response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0002385//mucosal immune response;GO:0050691//regulation of defense response to virus by host,GO:0005515//protein binding;GO:0004896//cytokine receptor activity,K05140//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
163720,13,0,0,5,0,0,10,0,0,0,0,0,"CYP4Z2P;cytochrome P450, family 4, subfamily Z, polypeptide 2, pseudogene",GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,"GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding;GO:0020037//heme binding",K07428//Serotonergic synapse
163732,96,0,0,0,0,0,0,0,0,0,0,1,"CITED4;Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043627//response to estrogen;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003713//transcription coactivator activity,-
163747,0,0,0,0,0,24,0,0,14,18,8,294,C1orf177;chromosome 1 open reading frame 177,-,-,-,-
163778,41,0,0,0,0,0,30,0,10,0,5,0,SPRR4;small proline-rich protein 4,GO:0005938//cell cortex,GO:0018149//peptide cross-linking;GO:0031424//keratinization,-,-
163782,119,0,0,0,0,19,1,4,27,0,10,0,KANK4;KN motif and ankyrin repeat domains 4,GO:0005737//cytoplasm,-,-,K08803//Bladder cancer;Pathways in cancer;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
163786,0,0,0,0,0,45,0,0,19,0,0,0,SASS6;spindle assembly 6 homolog (C. elegans),GO:0005813//centrosome;GO:0005814//centriole;GO:0098536//deuterosome,GO:0051298//centrosome duplication;GO:0007099//centriole replication,GO:0005515//protein binding,K12478//Tuberculosis;Endocytosis;Phagosome;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton
1638,0,0,0,0,0,0,0,29,34,0,0,308,DCT;dopachrome tautomerase,GO:0005829//cytosol;GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0033162//melanosome membrane,GO:0006583//melanin biosynthetic process from tyrosine;GO:0055114//oxidation-reduction process;GO:0021847//ventricular zone neuroblast division;GO:0048066//developmental pigmentation;GO:0008544//epidermis development;GO:0002052//positive regulation of neuroblast proliferation;GO:0048468//cell development,GO:0004167//dopachrome isomerase activity;GO:0005507//copper ion binding;GO:0016491//oxidoreductase activity,K01827//Metabolic pathways;Tyrosine metabolism;Melanogenesis
163859,0,0,0,6,3,0,0,61,17,0,0,0,SDE2;SDE2 telomere maintenance homolog (S. pombe),-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
163882,0,31,0,33,0,40,0,0,56,0,0,0,"CNST;consortin, connexin sorting protein",GO:0030133//transport vesicle;GO:0005802//trans-Golgi network;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0010923//negative regulation of phosphatase activity;GO:0042998//positive regulation of Golgi to plasma membrane protein transport,GO:0005515//protein binding;GO:0071253//connexin binding;GO:0019902//phosphatase binding,-
1639,71,41,1,15,4,1,78,46,55,0,0,0,DCTN1;dynactin 1,GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005829//cytosol;GO:0030286//dynein complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005869//dynactin complex;GO:0000776//kinetochore;GO:0031252//cell leading edge,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007399//nervous system development;GO:0008219//cell death;GO:0032402//melanosome transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0010970//microtubule-based transport;GO:0007067//mitotic nuclear division,GO:0045502//dynein binding;GO:0005515//protein binding;GO:0003774//motor activity,K04648//Vasopressin-regulated water reabsorption;Huntington's disease
163933,0,0,11,0,0,0,0,0,25,0,0,0,"FAM43B;family with sequence similarity 43, member B",-,-,-,-
164,0,190,1,138,388,10,68,0,65,0,17,0,"AP1G1;adaptor-related protein complex 1, gamma 1 subunit",GO:0005794//Golgi apparatus;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0030131//clathrin adaptor complex;GO:0030665//clathrin-coated vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0030119//AP-type membrane coat adaptor complex,GO:0006886//intracellular protein transport;GO:0043323//positive regulation of natural killer cell degranulation;GO:0016032//viral process;GO:0090160//Golgi to lysosome transport;GO:0050690//regulation of defense response to virus by virus;GO:0061024//membrane organization;GO:0032438//melanosome organization;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0006892//post-Golgi vesicle-mediated transport;GO:0035646//endosome to melanosome transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0019894//kinesin binding;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding;GO:0017137//Rab GTPase binding;GO:0008565//protein transporter activity;GO:0005215//transporter activity,K12391//Lysosome
164045,0,25,0,0,0,76,0,62,82,0,0,0,"HFM1;HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)",-,GO:0000712//resolution of meiotic recombination intermediates,GO:0004386//helicase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding,-
164091,0,0,0,1,0,0,0,0,11,0,1,0,PAQR7;progestin and adipoQ receptor family member VII,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0043401//steroid hormone mediated signaling pathway;GO:0007275//multicellular organismal development;GO:0048477//oogenesis;GO:0048545//response to steroid hormone,GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding,K11447//Transcriptional misregulation in cancer;K07987//Natural killer cell mediated cytotoxicity;K07297//Adipocytokine signaling pathway
1641,33,0,0,0,0,27,0,0,25,0,0,0,DCX;doublecortin,GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0043005//neuron projection;GO:0005829//cytosol,GO:0007417//central nervous system development;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0035556//intracellular signal transduction;GO:0007420//brain development;GO:0048675//axon extension;GO:0048813//dendrite morphogenesis;GO:0001764//neuron migration,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding,-
164118,101,0,0,0,0,0,24,0,21,0,0,0,TTC24;tetratricopeptide repeat domain 24,-,-,-,K15839//Cocaine addiction
164127,0,0,0,0,0,11,0,0,42,0,0,0,CCDC185;coiled-coil domain containing 185,-,-,-,-
164153,0,0,0,0,0,0,0,0,10,114,0,0,UBL4B;ubiquitin-like 4B,GO:0005737//cytoplasm,-,-,K02927//Ribosome;K02977//Ribosome
1642,0,107,6,91,315,0,12,11,101,145,18,0,"DDB1;damage-specific DNA binding protein 1, 127kDa",GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005615//extracellular space;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0005634//nucleus;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0043066//negative regulation of apoptotic process;GO:0070914//UV-damage excision repair;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006289//nucleotide-excision repair;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0035518//histone H2A monoubiquitination;GO:0006281//DNA repair;GO:0016055//Wnt signaling pathway;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0016032//viral process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process",GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,K10610//Nucleotide excision repair;Ubiquitin mediated proteolysis
164237,0,0,43,0,0,0,8,0,29,0,0,232,WFDC13;WAP four-disulfide core domain 13,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K04658//TGF-beta signaling pathway
164284,42,0,0,0,0,0,0,0,3,1,23,0,APCDD1L;adenomatosis polyposis coli down-regulated 1-like,GO:0016021//integral component of membrane,-,-,-
164312,0,0,0,9,0,21,0,0,0,0,1,0,LRRN4;leucine rich repeat neuronal 4,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0008542//visual learning;GO:0007616//long-term memory,-,K07523//Axon guidance
164380,0,0,0,0,0,0,0,0,18,0,0,0,"CST13P;cystatin 13, pseudogene",-,-,-,-
164395,78,0,0,0,0,0,57,0,64,0,0,0,"TTLL9;tubulin tyrosine ligase-like family, member 9",GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005929//cilium,GO:0006464//cellular protein modification process,GO:0016874//ligase activity,"K05755//Regulation of actin cytoskeleton;Salmonella infection;Bacterial invasion of epithelial cells;Shigellosis;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis;K00273//Metabolic pathways;Peroxisome;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism"
1644,0,0,0,0,4,0,60,7,67,21,0,0,DDC;dopa decarboxylase (aromatic L-amino acid decarboxylase),GO:0008021//synaptic vesicle;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0030424//axon;GO:0043025//neuronal cell body,GO:0033076//isoquinoline alkaloid metabolic process;GO:0044281//small molecule metabolic process;GO:0046684//response to pyrethroid;GO:0035690//cellular response to drug;GO:0042427//serotonin biosynthetic process;GO:0042423//catecholamine biosynthetic process;GO:0052314//phytoalexin metabolic process;GO:0015842//synaptic vesicle amine transport;GO:0042416//dopamine biosynthetic process;GO:0071312//cellular response to alkaloid;GO:0010259//multicellular organismal aging;GO:0046219//indolalkylamine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0007623//circadian rhythm;GO:0006520//cellular amino acid metabolic process,GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0016597//amino acid binding;GO:0030170//pyridoxal phosphate binding;GO:0005515//protein binding;GO:0004058//aromatic-L-amino-acid decarboxylase activity,K01593//Isoquinoline alkaloid biosynthesis;Dopaminergic synapse;Cocaine addiction;Histidine metabolism;Alcoholism;Serotonergic synapse;Biosynthesis of secondary metabolites;Betalain biosynthesis;Tryptophan metabolism;Amphetamine addiction;Metabolic pathways;Tyrosine metabolism;Phenylalanine metabolism
1645,0,0,0,0,0,0,0,0,1,0,0,0,"AKR1C1;aldo-keto reductase family 1, member C1",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0055114//oxidation-reduction process;GO:0042448//progesterone metabolic process;GO:0042632//cholesterol homeostasis;GO:0042574//retinal metabolic process;GO:0030299//intestinal cholesterol absorption;GO:0030855//epithelial cell differentiation;GO:0007586//digestion;GO:0046683//response to organophosphorus;GO:0007603//phototransduction, visible light;GO:0044597//daunorubicin metabolic process;GO:0008206//bile acid metabolic process;GO:0051260//protein homooligomerization;GO:0001523//retinoid metabolic process;GO:0071395//cellular response to jasmonic acid stimulus;GO:0044598//doxorubicin metabolic process;GO:0015721//bile acid and bile salt transport;GO:0006805//xenobiotic metabolic process","GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0032052//bile acid binding;GO:0004033//aldo-keto reductase (NADP) activity;GO:0031406//carboxylic acid binding;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0047718//indanol dehydrogenase activity;GO:0047042//androsterone dehydrogenase (B-specific) activity;GO:0047086//ketosteroid monooxygenase activity;GO:0047006//17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity;GO:0018636//phenanthrene 9,10-monooxygenase activity","K00092//Metabolic pathways;Primary bile acid biosynthesis;Steroid hormone biosynthesis;Metabolism of xenobiotics by cytochrome P450;K00100//Chloroalkane and chloroalkene degradation;Limonene and pinene degradation;Two-component system;Naphthalene degradation;Fructose and mannose metabolism;Linoleic acid metabolism;Metabolic pathways;Methane metabolism;Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Benzoate degradation;Bisphenol degradation;Microbial metabolism in diverse environments;Butanoate metabolism;K00212//Arachidonic acid metabolism;Metabolic pathways;Primary bile acid biosynthesis;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00037//Primary bile acid biosynthesis;Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00089//Steroid hormone biosynthesis;Metabolism of xenobiotics by cytochrome P450;Metabolic pathways;Primary bile acid biosynthesis;Arachidonic acid metabolism;K05295//Steroid hormone biosynthesis"
164592,0,0,0,0,0,7,0,0,31,0,3,0,CCDC116;coiled-coil domain containing 116,-,-,-,-
1646,51,0,0,0,0,17,3,0,16,0,0,0,"AKR1C2;aldo-keto reductase family 1, member C2",GO:0005737//cytoplasm,GO:0034694//response to prostaglandin;GO:0008284//positive regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0071395//cellular response to jasmonic acid stimulus;GO:0007586//digestion;GO:0044598//doxorubicin metabolic process;GO:0006693//prostaglandin metabolic process;GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0042448//progesterone metabolic process;GO:0044597//daunorubicin metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030855//epithelial cell differentiation,"GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0047086//ketosteroid monooxygenase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0031406//carboxylic acid binding;GO:0032052//bile acid binding;GO:0004958//prostaglandin F receptor activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor","K00092//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Metabolic pathways;Primary bile acid biosynthesis;K00100//Benzoate degradation;Butanoate metabolism;Microbial metabolism in diverse environments;Bisphenol degradation;Biosynthesis of secondary metabolites;Methane metabolism;Glycine, serine and threonine metabolism;Linoleic acid metabolism;Two-component system;Fructose and mannose metabolism;Naphthalene degradation;Metabolic pathways;Chloroalkane and chloroalkene degradation;Limonene and pinene degradation;K00212//Arachidonic acid metabolism;Metabolic pathways;Primary bile acid biosynthesis;Steroid hormone biosynthesis;Metabolism of xenobiotics by cytochrome P450;K00037//Primary bile acid biosynthesis;Metabolic pathways;Steroid hormone biosynthesis;Metabolism of xenobiotics by cytochrome P450;K00089//Primary bile acid biosynthesis;Metabolic pathways;Arachidonic acid metabolism;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K05295//Steroid hormone biosynthesis"
164633,0,262,74,191,180,0,0,1,76,0,559,0,CABP7;calcium binding protein 7,GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm,-,GO:0005509//calcium ion binding,-
164656,0,0,0,3,0,15,25,1,8,158,0,0,"TMPRSS6;transmembrane protease, serine 6",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0001525//angiogenesis;GO:0035556//intracellular signal transduction;GO:0055072//iron ion homeostasis;GO:0006508//proteolysis;GO:0042730//fibrinolysis;GO:0030198//extracellular matrix organization,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,-
164668,87,0,0,1,0,14,14,0,0,0,0,0,"APOBEC3H;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H",GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus,GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0010529//negative regulation of transposition;GO:0009972//cytidine deamination;GO:0048525//negative regulation of viral process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0070383//DNA cytosine deamination,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004126//cytidine deaminase activity,K01500//Microbial metabolism in diverse environments;Atrazine degradation;K10989//Intestinal immune network for IgA production;Primary immunodeficiency
164684,61,0,56,0,0,0,0,1,37,1,0,235,WBP2NL;WBP2 N-terminal like,GO:0033011//perinuclear theca,GO:0035039//male pronucleus assembly;GO:0007126//meiotic nuclear division;GO:0007343//egg activation,GO:0050699//WW domain binding,K03006//Herpes simplex infection;Huntington's disease;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection
1647,0,0,0,0,0,0,0,0,2,3,0,572,"GADD45A;growth arrest and DNA-damage-inducible, alpha",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007050//cell cycle arrest;GO:0006281//DNA repair;GO:0042770//signal transduction in response to DNA damage;GO:0006469//negative regulation of protein kinase activity;GO:1900745//positive regulation of p38MAPK cascade;GO:0000185//activation of MAPKKK activity;GO:0071479//cellular response to ionizing radiation;GO:0071260//cellular response to mechanical stimulus;GO:0046330//positive regulation of JNK cascade;GO:0007098//centrosome cycle;GO:0043065//positive regulation of apoptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006915//apoptotic process,GO:0001047//core promoter binding;GO:0005515//protein binding,K04402//NF-kappa B signaling pathway;MAPK signaling pathway;Cell cycle;p53 signaling pathway
164781,0,0,0,0,0,0,0,0,24,0,0,0,DAW1;dynein assembly factor with WDR repeat domains 1,GO:0005929//cilium,-,-,-
164832,0,0,1,9,19,0,34,0,63,0,0,9,LONRF2;LON peptidase N-terminal domain and ring finger 2,-,GO:0006200//ATP catabolic process;GO:0006508//proteolysis,GO:0004176//ATP-dependent peptidase activity;GO:0008270//zinc ion binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
1649,0,0,0,12,0,0,0,0,0,0,32,0,DDIT3;DNA-damage-inducible transcript 3,GO:0005770//late endosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0051209//release of sequestered calcium ion into cytosol;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043525//positive regulation of neuron apoptotic process;GO:0042594//response to starvation;GO:0044324//regulation of transcription involved in anterior/posterior axis specification;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045662//negative regulation of myoblast differentiation;GO:2000016//negative regulation of determination of dorsal identity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0001955//blood vessel maturation;GO:0045454//cell redox homeostasis;GO:0032757//positive regulation of interleukin-8 production;GO:0044267//cellular protein metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein;GO:0034976//response to endoplasmic reticulum stress;GO:0007050//cell cycle arrest;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0016055//Wnt signaling pathway;GO:0006983//ER overload response",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding,K04452//Protein processing in endoplasmic reticulum;MAPK signaling pathway;Transcriptional misregulation in cancer
165,0,0,0,0,0,9,22,1,21,0,5,1,AEBP1;AE binding protein 1,GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,"GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0001501//skeletal system development",GO:0004181//metallocarboxypeptidase activity;GO:0005516//calmodulin binding;GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0004180//carboxypeptidase activity,-
1650,95,10,0,20,17,11,21,1,0,0,0,0,DDOST;dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic),GO:0043234//protein complex;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0008250//oligosaccharyltransferase complex,GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0034097//response to cytokine;GO:0044267//cellular protein metabolic process;GO:0006487//protein N-linked glycosylation;GO:0042110//T cell activation;GO:0010467//gene expression;GO:0006486//protein glycosylation;GO:0045087//innate immune response;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine,GO:0004576//oligosaccharyl transferase activity;GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding,K12670//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
165055,0,1,0,0,10,0,26,0,13,0,0,15,CCDC138;coiled-coil domain containing 138,-,-,-,K12172//RNA transport
165082,0,21,105,56,93,6,0,41,74,0,71,0,GPR113;G protein-coupled receptor 113,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
165100,0,0,0,0,0,15,0,0,10,0,0,0,C2orf57;chromosome 2 open reading frame 57,-,-,-,-
165140,0,0,0,0,0,0,0,0,0,60,0,0,OXER1;oxoeicosanoid (OXE) receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0030817//regulation of cAMP biosynthetic process,"GO:0050647//5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding;GO:0050646//5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding;GO:0004930//G-protein coupled receptor activity;GO:0050648//5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding",-
165186,0,0,0,7,0,16,30,0,34,190,2,0,"FAM179A;family with sequence similarity 179, member A",-,-,-,-
1652,0,32,2,0,2,0,0,0,1,0,105,0,DDT;D-dopachrome tautomerase,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0042438//melanin biosynthetic process,GO:0004167//dopachrome isomerase activity;GO:0033981//D-dopachrome decarboxylase activity,-
165215,77,0,0,0,0,0,14,54,56,0,4,0,"FAM171B;family with sequence similarity 171, member B",GO:0016021//integral component of membrane,-,GO:0003677//DNA binding,-
165257,0,0,0,0,0,17,1,51,0,26,0,0,"C1QL2;complement component 1, q subcomponent-like 2",GO:0005581//collagen trimer;GO:0005576//extracellular region,GO:0051259//protein oligomerization,GO:0042802//identical protein binding,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
1653,0,1,1,59,79,16,47,0,66,0,0,0,DDX1;DEAD (Asp-Glu-Ala-Asp) box helicase 1,GO:0005737//cytoplasm;GO:0072669//tRNA-splicing ligase complex;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0071920//cleavage body;GO:0005730//nucleolus,"GO:0043330//response to exogenous dsRNA;GO:0006351//transcription, DNA-templated;GO:0000245//spliceosomal complex assembly;GO:0009615//response to virus;GO:0007275//multicellular organismal development;GO:0032508//DNA duplex unwinding;GO:0006446//regulation of translational initiation;GO:0006302//double-strand break repair;GO:0006200//ATP catabolic process;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006355//regulation of transcription, DNA-templated",GO:0033677//DNA/RNA helicase activity;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0004527//exonuclease activity;GO:0004518//nuclease activity;GO:0008143//poly(A) binding;GO:0003712//transcription cofactor activity;GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
165324,0,0,0,0,0,0,0,0,10,0,0,0,UBXN2A;UBX domain protein 2A,GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005801//cis-Golgi network,GO:0010468//regulation of gene expression;GO:0042176//regulation of protein catabolic process;GO:0031396//regulation of protein ubiquitination,GO:0033130//acetylcholine receptor binding,K14012//Protein processing in endoplasmic reticulum
1654,1,0,1,68,139,21,0,0,13,0,0,0,"DDX3X;DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked",GO:0016607//nuclear speck;GO:0022627//cytosolic small ribosomal subunit;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm,"GO:0030307//positive regulation of cell growth;GO:0031333//negative regulation of protein complex assembly;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0030308//negative regulation of cell growth;GO:0009615//response to virus;GO:0071470//cellular response to osmotic stress;GO:0034063//stress granule assembly;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0097193//intrinsic apoptotic signaling pathway;GO:0032508//DNA duplex unwinding;GO:0043066//negative regulation of apoptotic process;GO:0045087//innate immune response;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0032728//positive regulation of interferon-beta production;GO:0042256//mature ribosome assembly;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0071243//cellular response to arsenic-containing substance;GO:0010501//RNA secondary structure unwinding;GO:0007059//chromosome segregation;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045948//positive regulation of translational initiation;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0045727//positive regulation of translation;GO:0017148//negative regulation of translation;GO:0006200//ATP catabolic process",GO:0008143//poly(A) binding;GO:0035613//RNA stem-loop binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0043024//ribosomal small subunit binding;GO:0003723//RNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0008190//eukaryotic initiation factor 4E binding;GO:0031369//translation initiation factor binding;GO:0016887//ATPase activity;GO:0003677//DNA binding;GO:0048027//mRNA 5'-UTR binding,K11594//RIG-I-like receptor signaling pathway
1655,0,201,1,56,316,0,0,0,61,0,0,0,DDX5;DEAD (Asp-Glu-Ala-Asp) box helicase 5,GO:0071013//catalytic step 2 spliceosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:2001014//regulation of skeletal muscle cell differentiation;GO:0016049//cell growth;GO:0001701//in utero embryonic development;GO:0045069//regulation of viral genome replication;GO:0007623//circadian rhythm;GO:0045667//regulation of osteoblast differentiation;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome;GO:0006200//ATP catabolic process;GO:0060765//regulation of androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0048306//calcium-dependent protein binding;GO:0019899//enzyme binding;GO:0036002//pre-mRNA binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0030331//estrogen receptor binding;GO:0003724//RNA helicase activity,K12823//Spliceosome;Transcriptional misregulation in cancer
165530,99,0,0,0,0,0,41,40,17,0,0,0,"CLEC4F;C-type lectin domain family 4, member F",GO:0016021//integral component of membrane,GO:0006897//endocytosis,GO:0030246//carbohydrate binding,-
165545,0,0,0,0,0,0,0,0,70,0,10,0,DQX1;DEAQ box RNA-dependent ATPase 1,GO:0005634//nucleus,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0004386//helicase activity,-
1656,0,151,1,131,430,9,33,1,66,65,18,0,DDX6;DEAD (Asp-Glu-Ala-Asp) box helicase 6,GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0016020//membrane;GO:0016442//RISC complex;GO:0000932//cytoplasmic mRNA processing body;GO:0010494//cytoplasmic stress granule;GO:0005737//cytoplasm,"GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0033962//cytoplasmic mRNA processing body assembly",GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003724//RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008026//ATP-dependent helicase activity,K12614//RNA degradation
165631,0,0,0,1,0,0,46,0,42,0,0,0,"PARP15;poly (ADP-ribose) polymerase family, member 15",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003950//NAD+ ADP-ribosyltransferase activity,-
165679,0,0,0,8,35,0,0,40,33,0,5,0,"SPTSSB;serine palmitoyltransferase, small subunit B",GO:0017059//serine C-palmitoyltransferase complex;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030148//sphingolipid biosynthetic process,GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding,-
1657,27,237,39,206,1242,0,0,0,169,0,3,0,DMXL1;Dmx-like 1,-,-,-,K11447//Transcriptional misregulation in cancer;K14209//Protein digestion and absorption;K14555//Ribosome biogenesis in eukaryotes;K07972//Phototransduction - fly;MAPK signaling pathway - yeast;K12602//RNA degradation;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
165721,0,0,0,8,0,4,0,0,5,0,0,0,"DNAJB8;DnaJ (Hsp40) homolog, subfamily B, member 8",GO:0005634//nucleus;GO:0005829//cytosol,GO:0090084//negative regulation of inclusion body assembly;GO:0061077//chaperone-mediated protein folding,GO:0044183//protein binding involved in protein folding;GO:0051082//unfolded protein binding;GO:0051087//chaperone binding,-
165829,0,0,0,11,0,23,20,0,0,129,0,0,GPR156;G protein-coupled receptor 156,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004965//G-protein coupled GABA receptor activity,K04617//Neuroactive ligand-receptor interaction
1659,0,1,1,15,47,0,1,0,25,0,0,0,DHX8;DEAH (Asp-Glu-Ala-His) box polypeptide 8,GO:0005634//nucleus;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0006200//ATP catabolic process;GO:0008380//RNA splicing",GO:0042802//identical protein binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding,K12818//Spliceosome
165904,120,0,0,0,0,61,0,21,0,0,0,0,XIRP1;xin actin-binding repeat containing 1,GO:0005916//fascia adherens,GO:0008285//negative regulation of cell proliferation;GO:0042391//regulation of membrane potential;GO:0055013//cardiac muscle cell development;GO:0045214//sarcomere organization,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003779//actin binding,-
165918,0,0,0,0,49,3,0,44,43,0,0,0,"RNF168;ring finger protein 168, E3 ubiquitin protein ligase",GO:0005739//mitochondrion;GO:0035861//site of double-strand break;GO:0005730//nucleolus;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus,GO:0070534//protein K63-linked ubiquitination;GO:0016567//protein ubiquitination;GO:0045739//positive regulation of DNA repair;GO:0036297//interstrand cross-link repair;GO:0045190//isotype switching;GO:0010212//response to ionizing radiation;GO:0036351//histone H2A-K13 ubiquitination;GO:0045900//negative regulation of translational elongation;GO:0035518//histone H2A monoubiquitination;GO:0006302//double-strand break repair;GO:0036352//histone H2A-K15 ubiquitination;GO:0070535//histone H2A K63-linked ubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0042393//histone binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0043130//ubiquitin binding;GO:0070530//K63-linked polyubiquitin binding;GO:0016874//ligase activity;GO:0031491//nucleosome binding;GO:0003682//chromatin binding,K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
166,0,17,0,41,107,0,0,0,7,0,1,0,AES;amino-terminal enhancer of split,GO:0005634//nucleus,"GO:0070555//response to interleukin-1;GO:0010629//negative regulation of gene expression;GO:0016055//Wnt signaling pathway;GO:2000210//positive regulation of anoikis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060761//negative regulation of response to cytokine stimulus;GO:0009887//organ morphogenesis;GO:0032091//negative regulation of protein binding;GO:0007275//multicellular organismal development",GO:0005515//protein binding;GO:0003714//transcription corepressor activity,K04497//Wnt signaling pathway;Notch signaling pathway
1660,95,168,2,48,152,59,0,2,64,180,0,0,DHX9;DEAH (Asp-Glu-Ala-His) box helicase 9,GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0070937//CRD-mediated mRNA stability complex,"GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0001649//osteoblast differentiation;GO:0034605//cellular response to heat;GO:0006200//ATP catabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0070934//CRD-mediated mRNA stabilization;GO:0007623//circadian rhythm;GO:0032508//DNA duplex unwinding;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0001085//RNA polymerase II transcription factor binding;GO:0003724//RNA helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004004//ATP-dependent RNA helicase activity,-
166012,0,0,0,0,0,14,0,0,0,0,0,0,CHST13;carbohydrate (chondroitin 4) sulfotransferase 13,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0016051//carbohydrate biosynthetic process,GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity;GO:0047756//chondroitin 4-sulfotransferase activity,K07779//Glycosaminoglycan biosynthesis - chondroitin sulfate;Sulfur metabolism
1662,0,0,0,23,41,0,0,53,41,0,7,0,DDX10;DEAD (Asp-Glu-Ala-Asp) box polypeptide 10,-,GO:0006200//ATP catabolic process;GO:0008152//metabolic process,GO:0003724//RNA helicase activity;GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
1663,0,0,0,0,12,12,30,56,1,13,13,161,DDX11;DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0030496//midbody;GO:0005730//nucleolus,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006200//ATP catabolic process;GO:0032508//DNA duplex unwinding;GO:0016032//viral process;GO:0007062//sister chromatid cohesion;GO:0006987//activation of signaling protein activity involved in unfolded protein response,"GO:0003697//single-stranded DNA binding;GO:0004386//helicase activity;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003690//double-stranded DNA binding;GO:0008094//DNA-dependent ATPase activity",-
166336,44,0,0,0,7,9,20,0,39,0,0,0,PRICKLE2;prickle homolog 2 (Drosophila),GO:0005737//cytoplasm;GO:0016327//apicolateral plasma membrane;GO:0016328//lateral plasma membrane;GO:0031965//nuclear membrane,GO:0031175//neuron projection development;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity,GO:0008270//zinc ion binding,K04511//Wnt signaling pathway
166348,0,0,0,0,0,0,37,0,38,0,0,0,KBTBD12;kelch repeat and BTB (POZ) domain containing 12,-,-,-,-
166378,0,16,1,23,1,15,33,0,94,150,13,0,SPATA5;spermatogenesis associated 5,GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0005524//ATP binding,K14575//Ribosome biogenesis in eukaryotes
166379,0,0,0,7,0,0,0,0,34,7,0,0,BBS12;Bardet-Biedl syndrome 12,GO:0005929//cilium,GO:0051131//chaperone-mediated protein complex assembly;GO:0042755//eating behavior;GO:0045494//photoreceptor cell maintenance;GO:0044267//cellular protein metabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0042073//intraciliary transport,GO:0005515//protein binding;GO:0005524//ATP binding,-
1665,0,77,33,78,209,0,1,71,57,0,1,0,DHX15;DEAH (Asp-Glu-Ala-His) box helicase 15,GO:0071008//U2-type post-mRNA release spliceosomal complex;GO:0005730//nucleolus;GO:0005689//U12-type spliceosomal complex;GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006200//ATP catabolic process;GO:0006397//mRNA processing,GO:0005524//ATP binding;GO:0003724//RNA helicase activity;GO:0003725//double-stranded RNA binding;GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12820//Spliceosome
1666,0,38,0,51,83,0,0,0,29,0,2,0,"DECR1;2,4-dienoyl CoA reductase 1, mitochondrial",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0051289//protein homotetramerization;GO:0044255//cellular lipid metabolic process;GO:0006635//fatty acid beta-oxidation,"GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0070402//NADPH binding;GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity",-
166614,0,0,0,0,22,16,50,0,56,121,0,0,DCLK2;doublecortin-like kinase 2,GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
166647,0,0,0,0,0,20,43,0,4,0,0,0,GPR125;G protein-coupled receptor 125,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
166655,0,0,0,0,0,0,1,0,21,0,0,0,TRIM60;tripartite motif containing 60,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
166752,0,0,0,0,7,13,0,91,44,182,7,1,FREM3;FRAS1 related extracellular matrix 3,GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0016021//integral component of membrane,GO:0007154//cell communication;GO:0007155//cell adhesion,GO:0046872//metal ion binding,-
166785,0,0,0,17,27,0,28,0,18,0,0,0,MMAA;methylmalonic aciduria (cobalamin deficiency) cblA type,GO:0005759//mitochondrial matrix,GO:0009236//cobalamin biosynthetic process;GO:0006766//vitamin metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0019626//short-chain fatty acid catabolic process;GO:0009235//cobalamin metabolic process;GO:0044255//cellular lipid metabolic process,GO:0005525//GTP binding;GO:0016787//hydrolase activity,-
166793,0,0,0,0,0,6,0,0,17,118,0,0,ZBTB49;zinc finger and BTB domain containing 49,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
166815,0,0,0,28,0,0,0,0,0,0,0,0,TIGD2;tigger transposable element derived 2,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
166824,0,0,0,1,17,12,1,0,9,0,49,0,RASSF6;Ras association (RalGDS/AF-6) domain family member 6,-,GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0007165//signal transduction,GO:0005515//protein binding,-
166863,0,0,0,0,0,0,29,0,38,0,0,0,RBM46;RNA binding motif protein 46,-,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
1669,0,0,0,0,0,12,0,0,0,0,3,0,"DEFA4;defensin, alpha 4, corticostatin",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005796//Golgi lumen,GO:0045087//innate immune response;GO:0019731//antibacterial humoral response;GO:0050832//defense response to fungus;GO:0031640//killing of cells of other organism,-,K05230//Transcriptional misregulation in cancer
166929,9,0,0,13,47,0,0,0,95,203,12,524,SGMS2;sphingomyelin synthase 2,GO:0005794//Golgi apparatus;GO:0045203//integral component of cell outer membrane;GO:0030173//integral component of Golgi membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030148//sphingolipid biosynthetic process;GO:0006686//sphingomyelin biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0016310//phosphorylation,GO:0047493//ceramide cholinephosphotransferase activity;GO:0033188//sphingomyelin synthase activity;GO:0016301//kinase activity,K04714//Metabolic pathways;Sphingolipid metabolism
166968,0,59,1,28,75,17,22,13,67,98,0,0,"MIER3;mesoderm induction early response 1, family member 3",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
166979,177,0,2,4,0,10,8,0,6,0,0,0,CDC20B;cell division cycle 20B,-,-,-,K03363//HTLV-I infection;Oocyte meiosis;Meiosis - yeast;Cell cycle - yeast;Ubiquitin mediated proteolysis;Cell cycle
167,0,0,0,0,0,10,17,0,18,0,0,0,CRISP1;cysteine-rich secretory protein 1,GO:0005634//nucleus;GO:0005615//extracellular space,GO:0007342//fusion of sperm to egg plasma membrane;GO:0007339//binding of sperm to zona pellucida;GO:0060046//regulation of acrosome reaction,GO:0005246//calcium channel regulator activity,-
1671,0,0,0,0,0,0,0,0,29,0,0,0,"DEFA6;defensin, alpha 6, Paneth cell-specific",GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005615//extracellular space,GO:0031640//killing of cells of other organism;GO:0019731//antibacterial humoral response;GO:0050832//defense response to fungus;GO:0045087//innate immune response,-,K05230//Transcriptional misregulation in cancer
167127,0,0,0,0,0,0,46,0,28,0,0,0,"UGT3A2;UDP glycosyltransferase 3 family, polypeptide A2",GO:0016021//integral component of membrane,GO:0008152//metabolic process;GO:0071412//cellular response to genistein,GO:0015020//glucuronosyltransferase activity,K00699//Metabolic pathways;Pentose and glucuronate interconversions;Drug metabolism - cytochrome P450;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;K04628//Metabolic pathways;Sphingolipid metabolism
1672,0,0,0,0,0,0,0,0,5,0,0,0,"DEFB1;defensin, beta 1",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen;GO:0005615//extracellular space,GO:0009617//response to bacterium;GO:0045087//innate immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0002526//acute inflammatory response;GO:0002227//innate immune response in mucosa;GO:0033574//response to testosterone;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0019731//antibacterial humoral response;GO:0007186//G-protein coupled receptor signaling pathway,-,-
167227,0,64,71,25,184,7,7,0,55,0,0,0,DCP2;decapping mRNA 2,GO:0016442//RISC complex;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005829//cytosol,"GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0071044//histone mRNA catabolic process;GO:0006402//mRNA catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0030145//manganese ion binding;GO:0016896//exoribonuclease activity, producing 5'-phosphomonoesters;GO:0005515//protein binding;GO:0003723//RNA binding;GO:0050072//m7G(5')pppN diphosphatase activity",K12613//RNA degradation
167359,0,0,0,0,0,16,0,0,46,0,0,0,NIM1K;NIM1 serine/threonine protein kinase,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,-
1674,0,0,0,0,0,0,0,0,28,0,2,0,DES;desmin,GO:0031594//neuromuscular junction;GO:0070062//extracellular vesicular exosome;GO:0042383//sarcolemma;GO:0005882//intermediate filament;GO:0005829//cytosol;GO:0005916//fascia adherens;GO:0030018//Z disc,GO:0006936//muscle contraction;GO:0007010//cytoskeleton organization;GO:0008016//regulation of heart contraction;GO:0030049//muscle filament sliding,GO:0005200//structural constituent of cytoskeleton;GO:0008092//cytoskeletal protein binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K07610//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
167410,0,0,0,0,0,0,12,0,0,0,0,0,LIX1;Lix1 homolog (chicken),-,-,-,K11447//Transcriptional misregulation in cancer
167465,0,0,0,0,0,17,0,0,37,0,0,0,ZNF366;zinc finger protein 366,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043627//response to estrogen",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0030331//estrogen receptor binding;GO:0003714//transcription corepressor activity,-
1675,0,0,0,0,0,11,0,19,0,0,0,0,CFD;complement factor D (adipsin),GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0006956//complement activation;GO:0007596//blood coagulation;GO:0045087//innate immune response;GO:0002576//platelet degranulation;GO:0006508//proteolysis;GO:0030168//platelet activation;GO:0006957//complement activation, alternative pathway",GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,K01334//Staphylococcus aureus infection;Complement and coagulation cascades
167555,0,51,0,7,1,0,0,29,26,0,35,0,"FAM151B;family with sequence similarity 151, member B",-,-,-,-
1676,0,0,1,11,4,20,1,0,0,0,10,0,"DFFA;DNA fragmentation factor, 45kDa, alpha polypeptide",GO:0005811//lipid particle;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:1902511//negative regulation of apoptotic DNA fragmentation;GO:0043065//positive regulation of apoptotic process;GO:0006309//apoptotic DNA fragmentation;GO:0070242//thymocyte apoptotic process;GO:0006915//apoptotic process;GO:1900118//negative regulation of execution phase of apoptosis,GO:0005515//protein binding,K02310//Apoptosis
167681,0,0,0,0,0,0,0,0,39,0,0,0,"PRSS35;protease, serine, 35",GO:0005739//mitochondrion;GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
167691,0,0,0,0,11,13,0,0,71,0,0,0,LCA5;Leber congenital amaurosis 5,GO:0005929//cilium;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm,GO:0042073//intraciliary transport;GO:0015031//protein transport;GO:0045494//photoreceptor cell maintenance,GO:0005515//protein binding;GO:0032403//protein complex binding,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K06674//Cell cycle - yeast
1677,0,0,0,0,0,19,29,0,4,0,0,0,"DFFB;DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)",GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007420//brain development;GO:0006309//apoptotic DNA fragmentation;GO:0030263//apoptotic chromosome condensation;GO:0006915//apoptotic process,GO:0019899//enzyme binding;GO:0004536//deoxyribonuclease activity;GO:0003677//DNA binding,K02311//Apoptosis
1678,0,13,0,0,1,0,38,0,0,0,0,0,TIMM8A;translocase of inner mitochondrial membrane 8 homolog A (yeast),GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion,GO:0072321//chaperone-mediated protein transport;GO:0044267//cellular protein metabolic process;GO:0007399//nervous system development;GO:0006626//protein targeting to mitochondrion,GO:0046872//metal ion binding,-
167826,0,0,0,0,0,0,0,0,13,0,3,0,OLIG3;oligodendrocyte transcription factor 3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0021520//spinal cord motor neuron cell fate specification;GO:0097476//spinal cord motor neuron migration;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
167838,0,0,0,0,0,0,50,34,20,85,17,0,TXLNB;taxilin beta,GO:0005737//cytoplasm,-,GO:0005515//protein binding;GO:0019905//syntaxin binding,K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
168002,0,0,0,0,0,0,13,0,44,0,11,77,DACT2;dishevelled-binding antagonist of beta-catenin 2,GO:0005739//mitochondrion,GO:0002244//hematopoietic progenitor cell differentiation;GO:1900108//negative regulation of nodal signaling pathway;GO:0007162//negative regulation of cell adhesion;GO:0043588//skin development;GO:0072061//inner medullary collecting duct development;GO:0003382//epithelial cell morphogenesis,GO:0070097//delta-catenin binding;GO:0051018//protein kinase A binding;GO:0008013//beta-catenin binding;GO:0005080//protein kinase C binding;GO:0008134//transcription factor binding,-
168090,0,0,0,0,0,0,0,57,0,0,0,0,C6orf118;chromosome 6 open reading frame 118,-,-,-,-
168374,2,0,0,0,11,14,0,0,20,0,0,0,ZNF92;zinc finger protein 92,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
168391,60,0,0,0,0,0,0,0,0,0,0,0,GALNTL5;polypeptide N-acetylgalactosaminyltransferase-like 5,GO:0016021//integral component of membrane;GO:0031902//late endosome membrane,GO:0006486//protein glycosylation;GO:0007286//spermatid development,"GO:0046872//metal ion binding;GO:0016757//transferase activity, transferring glycosyl groups",K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
168400,0,0,29,0,0,0,0,0,31,0,0,0,DDX53;DEAD (Asp-Glu-Ala-Asp) box polypeptide 53,GO:0005634//nucleus,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0008026//ATP-dependent helicase activity,K12823//Spliceosome;Transcriptional misregulation in cancer
168417,0,0,0,0,0,10,46,59,0,1,0,0,ZNF679;zinc finger protein 679,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
168433,0,0,0,0,0,0,0,0,12,0,0,0,RNF133;ring finger protein 133,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0051865//protein autoubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
168448,0,0,0,0,0,7,36,0,54,0,0,0,CDC14C;cell division cycle 14C,GO:0016021//integral component of membrane;GO:0005730//nucleolus,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K06639//Cell cycle - yeast;Cell cycle;Meiosis - yeast
168451,0,0,0,0,31,21,0,0,0,0,0,0,THAP5;THAP domain containing 5,GO:0005634//nucleus,GO:0007049//cell cycle;GO:0045786//negative regulation of cell cycle,GO:0002020//protease binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;K00943//Two-component system;One carbon pool by folate;Metabolic pathways;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
168455,0,1,0,13,28,0,0,0,6,0,19,0,CCDC71L;coiled-coil domain containing 71-like,-,-,-,-
168507,205,0,0,0,0,36,71,46,105,121,25,1,PKD1L1;polycystic kidney disease 1 like 1,GO:0005929//cilium;GO:0016020//membrane;GO:0060170//ciliary membrane;GO:0031513//nonmotile primary cilium;GO:0034704//calcium channel complex,GO:0016337//single organismal cell-cell adhesion;GO:0050982//detection of mechanical stimulus;GO:0070588//calcium ion transmembrane transport;GO:0070986//left/right axis specification;GO:0003127//detection of nodal flow,GO:0005262//calcium channel activity;GO:0005515//protein binding,-
168537,52,0,0,0,0,0,15,0,18,0,0,0,"GIMAP7;GTPase, IMAP family member 7",GO:0005811//lipid particle;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005525//GTP binding;GO:0003924//GTPase activity,K05305//Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism
168544,0,0,0,0,0,0,12,145,14,74,0,0,ZNF467;zinc finger protein 467,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
168620,0,0,0,0,0,0,5,0,0,0,17,0,"BHLHA15;basic helix-loop-helix family, member a15",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0048312//intracellular distribution of mitochondria;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007030//Golgi organization;GO:0007267//cell-cell signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048469//cell maturation;GO:0019722//calcium-mediated signaling;GO:0006851//mitochondrial calcium ion transport;GO:0042593//glucose homeostasis",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K08040//Maturity onset diabetes of the young
168667,75,0,0,0,0,66,21,0,24,0,4,0,BMPER;BMP binding endothelial regulator,GO:0005615//extracellular space,GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0001657//ureteric bud development;GO:0048839//inner ear development;GO:0030514//negative regulation of BMP signaling pathway;GO:0042118//endothelial cell activation;GO:0010594//regulation of endothelial cell migration,-,K03900//Complement and coagulation cascades;Focal adhesion;ECM-receptor interaction
1687,3,0,0,0,0,13,0,0,13,0,0,150,"DFNA5;deafness, autosomal dominant 5",GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0007605//sensory perception of sound;GO:0008285//negative regulation of cell proliferation;GO:0060113//inner ear receptor cell differentiation,-,-
168850,0,25,0,22,21,0,0,0,14,16,0,0,ZNF800;zinc finger protein 800,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
168975,0,0,0,0,0,1,0,0,37,0,0,0,CNBD1;cyclic nucleotide binding domain containing 1,-,-,-,-
1690,0,0,43,0,0,10,0,0,94,1,16,0,COCH;cochlin,GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix,GO:0007605//sensory perception of sound;GO:0045089//positive regulation of innate immune response;GO:0008360//regulation of cell shape;GO:0042742//defense response to bacterium,GO:0005515//protein binding,K06238//Focal adhesion;Protein digestion and absorption;ECM-receptor interaction
169026,0,0,0,0,0,21,6,0,29,0,0,0,"SLC30A8;solute carrier family 30 (zinc transporter), member 8",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0030667//secretory granule membrane;GO:0030658//transport vesicle membrane,GO:0071577//zinc ion transmembrane transport;GO:0032119//sequestering of zinc ion;GO:0006829//zinc ion transport;GO:0034341//response to interferon-gamma;GO:0055085//transmembrane transport;GO:0030073//insulin secretion;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose;GO:0070555//response to interleukin-1;GO:0060627//regulation of vesicle-mediated transport;GO:0042593//glucose homeostasis;GO:0061088//regulation of sequestering of zinc ion;GO:0006882//cellular zinc ion homeostasis,GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0005385//zinc ion transmembrane transporter activity,-
169044,36,0,11,0,0,0,42,41,106,0,31,199,"COL22A1;collagen, type XXII, alpha 1",GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix,GO:0030198//extracellular matrix organization,-,K08132//Protein digestion and absorption
169166,0,0,0,0,0,0,62,0,34,0,0,6,SNX31;sorting nexin 31,GO:0043234//protein complex,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding,-
169200,98,0,0,9,14,11,1,0,39,0,0,0,TMEM64;transmembrane protein 64,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0051480//cytosolic calcium ion homeostasis;GO:0043462//regulation of ATPase activity;GO:0045672//positive regulation of osteoclast differentiation;GO:0045780//positive regulation of bone resorption,-,-
169270,0,0,48,24,32,0,0,0,0,0,52,0,ZNF596;zinc finger protein 596,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
169355,0,0,0,6,0,0,58,0,27,0,0,285,"IDO2;indoleamine 2,3-dioxygenase 2",GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0055114//oxidation-reduction process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006569//tryptophan catabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0044281//small molecule metabolic process,"GO:0020037//heme binding;GO:0033754//indoleamine 2,3-dioxygenase activity;GO:0046872//metal ion binding;GO:0004833//tryptophan 2,3-dioxygenase activity",K00463//Tryptophan metabolism;African trypanosomiasis;Metabolic pathways
169436,0,0,0,18,11,25,15,0,56,0,26,29,STKLD1;serine/threonine kinase-like domain containing 1,-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004672//protein kinase activity,K05736//T cell receptor signaling pathway;Axon guidance;Regulation of actin cytoskeleton;ErbB signaling pathway;Renal cell carcinoma;Focal adhesion
169522,0,0,0,0,0,0,0,0,17,0,0,0,"KCNV2;potassium channel, subfamily V, member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0051260//protein homooligomerization;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity,-
169611,105,0,0,0,0,19,9,0,84,0,17,0,OLFML2A;olfactomedin-like 2A,GO:0031012//extracellular matrix;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization,GO:0050840//extracellular matrix binding;GO:0042803//protein homodimerization activity,-
169693,0,0,0,0,14,0,0,0,10,0,0,0,TMEM252;transmembrane protein 252,GO:0016021//integral component of membrane,-,-,-
169714,0,0,0,0,1,9,0,0,41,0,6,0,QSOX2;quiescin Q6 sulfhydryl oxidase 2,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane,GO:0055114//oxidation-reduction process;GO:0045454//cell redox homeostasis,GO:0016972//thiol oxidase activity,-
169792,0,0,0,0,10,1,0,0,69,0,0,0,GLIS3;GLIS family zinc finger 3,GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0046872//metal ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
169834,0,0,0,0,0,16,6,61,20,0,0,0,ZNF883;zinc finger protein 883,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
169966,0,0,0,0,0,0,0,0,10,0,0,0,"FAM46D;family with sequence similarity 46, member D",-,-,-,-
169981,0,39,0,6,63,1,0,0,40,0,0,0,"SPIN3;spindlin family, member 3",-,GO:0007276//gamete generation,-,-
170062,4,0,0,0,0,0,0,0,0,0,0,0,"FAM47B;family with sequence similarity 47, member B",-,-,-,K10798//NF-kappa B signaling pathway;Base excision repair
170063,0,0,0,0,0,33,24,0,10,0,0,0,CXorf22;chromosome X open reading frame 22,-,-,-,-
170067,0,0,0,0,0,0,0,0,26,0,0,0,SUPT20HL2;suppressor of Ty 20 homolog (S. cerevisiae)-like 2,GO:0005615//extracellular space;GO:0000124//SAGA complex,GO:2001141//regulation of RNA biosynthetic process,GO:0003712//transcription cofactor activity,-
170082,0,0,0,0,7,0,0,0,18,0,0,0,TCEANC;transcription elongation factor A (SII) N-terminal and central domain containing,GO:0005634//nucleus,"GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding,-
170261,0,0,0,0,0,0,13,0,26,0,1,0,"ZCCHC12;zinc finger, CCHC domain containing 12",GO:0016607//nuclear speck,"GO:0006351//transcription, DNA-templated;GO:0030509//BMP signaling pathway",GO:0003676//nucleic acid binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0008270//zinc ion binding,K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction
170302,24,0,0,0,0,0,2,36,18,0,0,421,ARX;aristaless related homeobox,GO:0005634//nucleus,"GO:0021831//embryonic olfactory bulb interneuron precursor migration;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0044241//lipid digestion;GO:0021759//globus pallidus development;GO:0072148//epithelial cell fate commitment;GO:0021800//cerebral cortex tangential migration;GO:0042127//regulation of cell proliferation;GO:0007411//axon guidance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046622//positive regulation of organ growth;GO:0006351//transcription, DNA-templated;GO:0021846//cell proliferation in forebrain",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
170370,0,0,0,0,0,7,0,1,5,0,7,0,"FAM170B;family with sequence similarity 170, member B",-,-,-,-
170371,0,0,0,0,0,0,0,0,18,251,1,1,C10orf128;chromosome 10 open reading frame 128,GO:0016021//integral component of membrane,-,-,-
170384,0,0,0,10,6,0,14,5,28,0,22,0,"FUT11;fucosyltransferase 11 (alpha (1,3) fucosyltransferase)",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0006486//protein glycosylation;GO:0036065//fucosylation,GO:0046920//alpha-(1->3)-fucosyltransferase activity,-
170392,0,0,0,0,0,0,0,0,27,0,0,4,OIT3;oncoprotein induced transcript 3,GO:0005635//nuclear envelope,-,GO:0005509//calcium ion binding,K04357//Bladder cancer;ErbB signaling pathway;Cytokine-cytokine receptor interaction;MAPK signaling pathway;Prostate cancer;Pancreatic cancer;Endocytosis;Pathways in cancer;Gap junction;Focal adhesion;Glioma;Hepatitis C;Melanoma;Regulation of actin cytoskeleton;Endometrial cancer;Non-small cell lung cancer
170393,0,0,0,0,0,0,29,0,6,0,2,0,C10orf91;chromosome 10 open reading frame 91,-,-,-,-
170394,0,0,0,0,3,0,0,1,21,0,0,0,PWWP2B;PWWP domain containing 2B,-,-,-,K00558//Folate biosynthesis;Cysteine and methionine metabolism;Metabolic pathways
170463,8,51,1,6,8,0,0,1,8,0,8,0,SSBP4;single stranded DNA binding protein 4,GO:0005634//nucleus,-,GO:0003697//single-stranded DNA binding,K11086//Spliceosome;Systemic lupus erythematosus;K12824//Spliceosome;K06236//ECM-receptor interaction;Amoebiasis;Protein digestion and absorption;Focal adhesion;K12831//Spliceosome
170482,0,0,0,0,0,25,18,0,0,3,0,0,"CLEC4C;C-type lectin domain family 4, member C",GO:0016021//integral component of membrane,GO:0045087//innate immune response,GO:0030246//carbohydrate binding,-
170487,0,17,0,0,19,0,3,0,15,0,6,0,ACTL10;actin-like 10,-,-,-,K05692//Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction
170506,4,2,0,12,47,0,0,0,19,0,4,0,DHX36;DEAH (Asp-Glu-Ala-His) box polypeptide 36,"GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0005829//cytosol","GO:0006200//ATP catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032481//positive regulation of type I interferon production;GO:0001503//ossification;GO:0045087//innate immune response;GO:0010501//RNA secondary structure unwinding;GO:0009615//response to virus;GO:0032206//positive regulation of telomere maintenance;GO:0043330//response to exogenous dsRNA;GO:0006351//transcription, DNA-templated",GO:0001047//core promoter binding;GO:0005524//ATP binding;GO:0042826//histone deacetylase binding;GO:0003725//double-stranded RNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0002151//G-quadruplex RNA binding;GO:0051880//G-quadruplex DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14442//RNA degradation
170572,0,0,0,0,0,0,0,0,18,0,0,0,"HTR3C;5-hydroxytryptamine (serotonin) receptor 3C, ionotropic",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport,GO:0005230//extracellular ligand-gated ion channel activity,K04819//Serotonergic synapse
170575,0,0,0,0,0,42,0,0,52,0,0,0,"GIMAP1;GTPase, IMAP family member 1",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030183//B cell differentiation;GO:0030217//T cell differentiation,GO:0005525//GTP binding,K11447//Transcriptional misregulation in cancer;K05305//Metabolic pathways;Fructose and mannose metabolism;Amino sugar and nucleotide sugar metabolism;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
170622,0,21,0,6,26,0,0,0,14,0,0,0,COMMD6;COMM domain containing 6,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0005515//protein binding;GO:0051059//NF-kappaB binding,-
170626,0,0,0,0,0,15,0,0,12,166,0,0,"XAGE3;X antigen family, member 3",-,-,GO:0005515//protein binding,-
170679,0,0,0,0,0,17,38,0,0,1,0,640,PSORS1C1;psoriasis susceptibility 1 candidate 1,-,-,-,-
170680,0,0,0,1,0,0,0,0,0,0,0,0,PSORS1C2;psoriasis susceptibility 1 candidate 2,GO:0005576//extracellular region,-,-,-
170685,0,0,0,0,1,0,0,0,0,0,0,0,NUDT10;nudix (nucleoside diphosphate linked moiety X)-type motif 10,GO:0005829//cytosol,GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process,"GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0046872//metal ion binding;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity",-
170689,3,0,0,0,0,53,0,0,48,3,9,0,"ADAMTS15;ADAM metallopeptidase with thrombospondin type 1 motif, 15",GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
170690,0,0,0,0,0,36,0,0,45,0,6,0,"ADAMTS16;ADAM metallopeptidase with thrombospondin type 1 motif, 16",GO:0005578//proteinaceous extracellular matrix,GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
170691,0,0,0,0,18,0,0,0,28,0,0,0,"ADAMTS17;ADAM metallopeptidase with thrombospondin type 1 motif, 17",GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
170692,0,0,0,0,18,22,23,80,1,24,6,0,"ADAMTS18;ADAM metallopeptidase with thrombospondin type 1 motif, 18",GO:0005578//proteinaceous extracellular matrix,GO:0090331//negative regulation of platelet aggregation;GO:0001654//eye development;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
170712,0,0,0,0,0,0,23,0,29,0,0,0,COX7B2;cytochrome c oxidase subunit VIIb2,GO:0016021//integral component of membrane;GO:0005746//mitochondrial respiratory chain,GO:1902600//hydrogen ion transmembrane transport,GO:0004129//cytochrome-c oxidase activity,K02271//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;Cardiac muscle contraction
170825,0,0,0,0,0,3,0,0,0,0,11,0,GSX2;GS homeobox 2,GO:0005634//nucleus,"GO:0021527//spinal cord association neuron differentiation;GO:0045747//positive regulation of Notch signaling pathway;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0021889//olfactory bulb interneuron differentiation;GO:0006351//transcription, DNA-templated;GO:0048853//forebrain morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030334//regulation of cell migration;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021575//hindbrain morphogenesis;GO:0021978//telencephalon regionalization;GO:0048665//neuron fate specification;GO:0048714//positive regulation of oligodendrocyte differentiation",GO:0043565//sequence-specific DNA binding,-
170850,0,0,0,0,0,0,0,0,50,0,0,0,"KCNG3;potassium voltage-gated channel, subfamily G, member 3",GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0051260//protein homooligomerization;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity;GO:0005515//protein binding,-
170958,2,15,0,15,17,32,22,0,35,0,9,0,ZNF525;zinc finger protein 525,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
170959,0,1,0,8,0,11,0,0,1,0,0,0,ZNF431;zinc finger protein 431,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation",GO:0003682//chromatin binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0046872//metal ion binding,-
170960,0,0,0,8,16,0,0,0,1,0,0,0,ZNF721;zinc finger protein 721,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
170961,0,0,0,0,1,0,14,11,16,7,15,0,ANKRD24;ankyrin repeat domain 24,-,-,-,-
171017,0,1,0,0,21,0,1,0,48,0,35,0,ZNF384;zinc finger protein 384,GO:0005925//focal adhesion;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006913//nucleocytoplasmic transport;GO:0050714//positive regulation of protein secretion",GO:0017124//SH3 domain binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
171019,0,0,0,0,1,69,47,0,69,24,12,0,"ADAMTS19;ADAM metallopeptidase with thrombospondin type 1 motif, 19",GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
171023,0,2,1,12,26,37,24,0,5,0,0,0,ASXL1;additional sex combs like transcriptional regulator 1,GO:0000790//nuclear chromatin;GO:0035517//PR-DUB complex;GO:0070062//extracellular vesicular exosome,"GO:0032526//response to retinoic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0035522//monoubiquitinated histone H2A deubiquitination;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0045599//negative regulation of fat cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060348//bone development",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042974//retinoic acid receptor binding;GO:0003677//DNA binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity,-
171024,0,0,1,6,0,5,53,0,52,0,0,0,SYNPO2;synaptopodin 2,GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc,-,GO:0005515//protein binding;GO:0071889//14-3-3 protein binding;GO:0003779//actin binding;GO:0051371//muscle alpha-actinin binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K05629//Tight junction;K11447//Transcriptional misregulation in cancer
171177,0,0,0,0,8,0,0,0,0,0,0,0,RHOV;ras homolog family member V,GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005525//GTP binding,-
171220,74,0,0,0,0,0,0,0,0,0,10,0,DSTNP2;destrin (actin depolymerizing factor) pseudogene 2,-,-,-,-
171389,0,0,0,0,3,0,25,0,21,38,0,556,"NLRP6;NLR family, pyrin domain containing 6",GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0005737//cytoplasm,GO:0009617//response to bacterium;GO:0043409//negative regulation of MAPK cascade;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050777//negative regulation of immune response;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0050727//regulation of inflammatory response;GO:0042060//wound healing;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005000//vasopressin receptor activity;GO:0005524//ATP binding,K12800//NOD-like receptor signaling pathway;Influenza A;Pertussis
171392,0,0,0,17,0,0,0,0,11,276,0,1,ZNF675;zinc finger protein 675,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0046329//negative regulation of JNK cascade;GO:0045453//bone resorption;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045671//negative regulation of osteoclast differentiation;GO:0043508//negative regulation of JUN kinase activity;GO:2000678//negative regulation of transcription regulatory region DNA binding",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
171423,0,0,0,1,1,0,0,0,0,0,0,0,"PDIA3P1;protein disulfide isomerase family A, member 3 pseudogene 1",-,-,-,K08056//Protein processing in endoplasmic reticulum;Antigen processing and presentation
171425,0,0,0,0,0,14,0,40,27,0,0,0,CLYBL;citrate lyase beta like,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016829//lyase activity,-
171482,0,0,0,0,0,32,0,4,7,0,0,0,"FAM9A;family with sequence similarity 9, member A",GO:0005730//nucleolus,-,GO:0005515//protein binding,-
171483,112,0,0,0,0,11,0,0,34,0,0,0,"FAM9B;family with sequence similarity 9, member B",GO:0005730//nucleolus;GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
171484,0,0,0,0,0,0,0,0,6,0,0,0,"FAM9C;family with sequence similarity 9, member C",GO:0005634//nucleus,-,-,-
171546,0,42,0,33,46,0,0,0,0,0,3,0,"SPTSSA;serine palmitoyltransferase, small subunit A",GO:0005789//endoplasmic reticulum membrane;GO:0017059//serine C-palmitoyltransferase complex;GO:0016021//integral component of membrane,GO:0030148//sphingolipid biosynthetic process,GO:0004758//serine C-palmitoyltransferase activity;GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption
171558,71,0,0,0,0,0,0,0,0,0,0,0,PTCRA;pre T-cell antigen receptor alpha,GO:0016021//integral component of membrane,GO:0070244//negative regulation of thymocyte apoptotic process,GO:0005515//protein binding,K06056//Notch signaling pathway;Transcriptional misregulation in cancer
171568,0,798,608,671,1051,16,20,793,91,0,1718,823,POLR3H;polymerase (RNA) III (DNA directed) polypeptide H (22.9kD),GO:0005813//centrosome;GO:0005634//nucleus;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol,GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0006139//nucleobase-containing compound metabolic process;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0032481//positive regulation of type I interferon production;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter,GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding;GO:0003899//DNA-directed RNA polymerase activity,K03022//Cytosolic DNA-sensing pathway;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase
171586,0,0,0,0,0,0,0,0,4,0,0,0,ABHD3;abhydrolase domain containing 3,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
1716,0,0,0,50,100,1,1,66,32,2,3,0,DGUOK;deoxyguanosine kinase,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0010977//negative regulation of neuron projection development;GO:0046070//dGTP metabolic process;GO:0044281//small molecule metabolic process;GO:0043101//purine-containing compound salvage;GO:0008617//guanosine metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006468//protein phosphorylation;GO:0009165//nucleotide biosynthetic process;GO:0046122//purine deoxyribonucleoside metabolic process,GO:0005524//ATP binding;GO:0004138//deoxyguanosine kinase activity;GO:0019206//nucleoside kinase activity,K00904//Metabolic pathways;Purine metabolism
1717,0,0,0,0,10,38,0,0,51,0,0,44,DHCR7;7-dehydrocholesterol reductase,GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0030154//cell differentiation;GO:0042127//regulation of cell proliferation;GO:0001568//blood vessel development;GO:0009791//post-embryonic development;GO:0044281//small molecule metabolic process;GO:0045540//regulation of cholesterol biosynthetic process;GO:0035264//multicellular organism growth;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process;GO:0030324//lung development,GO:0047598//7-dehydrocholesterol reductase activity,K00213//Biosynthesis of secondary metabolites;Metabolic pathways;Steroid biosynthesis
1718,0,23,0,20,54,6,15,0,30,0,0,0,DHCR24;24-dehydrocholesterol reductase,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0007265//Ras protein signal transduction;GO:0031639//plasminogen activation;GO:0044281//small molecule metabolic process;GO:0030539//male genitalia development;GO:0009888//tissue development;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1901214//regulation of neuron death;GO:0008104//protein localization;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0043588//skin development;GO:0007050//cell cycle arrest;GO:0009725//response to hormone;GO:0006979//response to oxidative stress;GO:0061024//membrane organization;GO:0042987//amyloid precursor protein catabolic process;GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006915//apoptotic process,"GO:0050660//flavin adenine dinucleotide binding;GO:0019899//enzyme binding;GO:0050614//delta24-sterol reductase activity;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0042605//peptide antigen binding;GO:0008762//UDP-N-acetylmuramate dehydrogenase activity",K09828//Steroid biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites
1719,0,0,0,21,69,12,0,0,21,0,7,0,DHFR;dihydrofolate reductase,-,-,-,K00287//Nicotinate and nicotinamide metabolism;Metabolic pathways;Terpenoid backbone biosynthesis;ABC transporters;One carbon pool by folate;Biosynthesis of secondary metabolites;Folate biosynthesis
172,0,0,0,0,0,0,0,0,22,0,7,0,"AFG3L1P;AFG3-like AAA ATPase 1, pseudogene",-,-,-,-
1723,2,0,0,0,0,26,36,0,16,6,32,0,DHODH;dihydroorotate dehydrogenase (quinone),GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0043025//neuronal cell body,GO:0007595//lactation;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0031000//response to caffeine;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0090140//regulation of mitochondrial fission;GO:0042594//response to starvation;GO:0006206//pyrimidine nucleobase metabolic process;GO:0044205//'de novo' UMP biosynthetic process;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0043065//positive regulation of apoptotic process,GO:0004158//dihydroorotate oxidase activity;GO:0008144//drug binding;GO:0048039//ubiquinone binding;GO:0010181//FMN binding,K00254//Metabolic pathways;Pyrimidine metabolism
1725,0,1,9,0,4,8,0,0,0,0,12,348,DHPS;deoxyhypusine synthase,GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0008612//peptidyl-lysine modification to peptidyl-hypusine;GO:0006412//translation;GO:0042593//glucose homeostasis;GO:0051289//protein homotetramerization;GO:0008284//positive regulation of cell proliferation;GO:0042102//positive regulation of T cell proliferation;GO:0043687//post-translational protein modification;GO:0050983//deoxyhypusine biosynthetic process from spermidine,GO:0034038//deoxyhypusine synthase activity;GO:0005515//protein binding,-
1727,217,0,0,0,38,0,7,0,3,0,1,1,CYB5R3;cytochrome b5 reductase 3,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0016020//membrane;GO:0005833//hemoglobin complex;GO:0005737//cytoplasm,GO:0019852//L-ascorbic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0008015//blood circulation;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process,"GO:0051287//NAD binding;GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0071949//FAD binding;GO:0016208//AMP binding;GO:0043531//ADP binding;GO:0050660//flavin adenine dinucleotide binding",K00326//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
1728,0,2,0,0,24,0,0,0,16,0,0,91,"NQO1;NAD(P)H dehydrogenase, quinone 1",GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0043086//negative regulation of catalytic activity;GO:0055114//oxidation-reduction process;GO:0043525//positive regulation of neuron apoptotic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0007584//response to nutrient;GO:0006809//nitric oxide biosynthetic process;GO:0045471//response to ethanol;GO:0034641//cellular nitrogen compound metabolic process;GO:0007568//aging;GO:0032355//response to estradiol;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0044281//small molecule metabolic process;GO:0019430//removal of superoxide radicals;GO:0007271//synaptic transmission, cholinergic","GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003955//NAD(P)H dehydrogenase (quinone) activity;GO:0004784//superoxide dismutase activity",K00355//Ubiquinone and other terpenoid-quinone biosynthesis
1729,0,46,1,101,120,46,25,0,39,0,8,0,DIAPH1;diaphanous-related formin 1,GO:0072686//mitotic spindle;GO:0032587//ruffle membrane;GO:0005737//cytoplasm,GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035372//protein localization to microtubule;GO:0007605//sensory perception of sound;GO:0007010//cytoskeleton organization;GO:0032886//regulation of microtubule-based process;GO:0030335//positive regulation of cell migration;GO:0008360//regulation of cell shape;GO:0071420//cellular response to histamine;GO:0030041//actin filament polymerization,GO:0003779//actin binding;GO:0005522//profilin binding;GO:0005102//receptor binding;GO:0044325//ion channel binding;GO:0017048//Rho GTPase binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K05740//Focal adhesion;Shigellosis;Regulation of actin cytoskeleton
173,0,0,0,0,0,14,0,0,48,0,0,0,AFM;afamin,GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0051180//vitamin transport,GO:0008431//vitamin E binding,K01883//Arginine and proline metabolism;Ribosome;DNA replication;Metabolic pathways;Aminoacyl-tRNA biosynthesis
1730,72,0,0,19,58,45,0,0,91,0,0,0,DIAPH2;diaphanous-related formin 2,GO:0005829//cytosol;GO:0005769//early endosome,GO:0048477//oogenesis;GO:0007275//multicellular organismal development;GO:0000910//cytokinesis;GO:0030041//actin filament polymerization;GO:0007292//female gamete generation,GO:0017048//Rho GTPase binding;GO:0005102//receptor binding;GO:0003779//actin binding,K05741//Regulation of actin cytoskeleton
1731,0,0,0,4,6,0,0,0,23,0,0,0,SEPT1;septin 1,GO:0030496//midbody;GO:0031105//septin complex;GO:0005815//microtubule organizing center,GO:0007049//cell cycle;GO:0051301//cell division,GO:0005525//GTP binding;GO:0005515//protein binding,K13737//Bacterial invasion of epithelial cells
1734,0,0,0,0,0,12,6,19,28,0,0,0,"DIO2;deiodinase, iodothyronine, type II",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0055114//oxidation-reduction process;GO:0042403//thyroid hormone metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0042446//hormone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006590//thyroid hormone generation;GO:0001514//selenocysteine incorporation,GO:0004800//thyroxine 5'-deiodinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0008430//selenium binding,-
1736,0,0,1,18,63,10,21,0,0,34,0,0,"DKC1;dyskeratosis congenita 1, dyskerin",GO:0005697//telomerase holoenzyme complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0015030//Cajal body;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007004//telomere maintenance via telomerase;GO:0000723//telomere maintenance;GO:0008283//cell proliferation;GO:0006396//RNA processing;GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing,GO:0009982//pseudouridine synthase activity;GO:0003720//telomerase activity;GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11131//Ribosome biogenesis in eukaryotes
1737,0,0,0,16,44,0,27,0,25,0,10,352,DLAT;dihydrolipoamide S-acetyltransferase,GO:0005967//mitochondrial pyruvate dehydrogenase complex;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0044237//cellular metabolic process;GO:0006006//glucose metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0004742//dihydrolipoyllysine-residue acetyltransferase activity,K00627//Ribosome;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;ABC transporters;Pyruvate metabolism;Citrate cycle (TCA cycle);Metabolic pathways;Two-component system
1738,0,0,1,21,41,0,24,0,5,0,1,0,DLD;dihydrolipoamide dehydrogenase,GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0043159//acrosomal matrix;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005929//cilium,"GO:0006090//pyruvate metabolic process;GO:0044237//cellular metabolic process;GO:0006554//lysine catabolic process;GO:0044281//small molecule metabolic process;GO:0007369//gastrulation;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0042391//regulation of membrane potential;GO:0006099//tricarboxylic acid cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0045454//cell redox homeostasis;GO:0006508//proteolysis;GO:0009083//branched-chain amino acid catabolic process;GO:0048240//sperm capacitation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate",GO:0004148//dihydrolipoyl dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding,"K00382//Glycine, serine and threonine metabolism;Cysteine and methionine metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Peptidoglycan biosynthesis;Valine, leucine and isoleucine degradation;Citrate cycle (TCA cycle);Metabolic pathways;Pyruvate metabolism;ABC transporters;Sulfur metabolism"
1739,10,33,1,44,120,20,0,75,64,0,0,0,"DLG1;discs, large homolog 1 (Drosophila)",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0009898//cytoplasmic side of plasma membrane;GO:0045211//postsynaptic membrane;GO:0005605//basal lamina;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0033268//node of Ranvier;GO:0042383//sarcolemma;GO:0005923//tight junction;GO:0005829//cytosol;GO:0035748//myelin sheath abaxonal region;GO:0031253//cell projection membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005874//microtubule;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0031594//neuromuscular junction;GO:0014704//intercalated disc;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane;GO:0014069//postsynaptic density;GO:0097025//MPP7-DLG1-LIN7 complex;GO:0016323//basolateral plasma membrane;GO:0043219//lateral loop;GO:0001772//immunological synapse;GO:0005634//nucleus,GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0007268//synaptic transmission;GO:0030838//positive regulation of actin filament polymerization;GO:0070830//tight junction assembly;GO:0031579//membrane raft organization;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0016311//dephosphorylation;GO:0072659//protein localization to plasma membrane;GO:0048745//smooth muscle tissue development;GO:1902305//regulation of sodium ion transmembrane transport;GO:0001771//immunological synapse formation;GO:0042391//regulation of membrane potential;GO:0007163//establishment or maintenance of cell polarity;GO:0007411//axon guidance;GO:0002369//T cell cytokine production;GO:0042130//negative regulation of T cell proliferation;GO:0030866//cortical actin cytoskeleton organization;GO:0007015//actin filament organization;GO:0043268//positive regulation of potassium ion transport;GO:0048704//embryonic skeletal system morphogenesis;GO:0016032//viral process;GO:0051898//negative regulation of protein kinase B signaling;GO:0046939//nucleotide phosphorylation;GO:0060022//hard palate development;GO:0042982//amyloid precursor protein metabolic process;GO:0032147//activation of protein kinase activity;GO:0030432//peristalsis;GO:0048608//reproductive structure development;GO:0031641//regulation of myelination;GO:0042110//T cell activation;GO:0016337//single organismal cell-cell adhesion;GO:0045930//negative regulation of mitotic cell cycle;GO:0007093//mitotic cell cycle checkpoint;GO:0008284//positive regulation of cell proliferation;GO:0001935//endothelial cell proliferation;GO:0002088//lens development in camera-type eye,GO:0031434//mitogen-activated protein kinase kinase binding;GO:0019901//protein kinase binding;GO:0015459//potassium channel regulator activity;GO:0004721//phosphoprotein phosphatase activity;GO:0008092//cytoskeletal protein binding;GO:0032947//protein complex scaffold;GO:0004385//guanylate kinase activity;GO:0008022//protein C-terminus binding;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0097016//L27 domain binding;GO:0019902//phosphatase binding,K12076//T cell receptor signaling pathway;HTLV-I infection
174,110,0,0,0,0,0,0,0,39,0,18,0,AFP;alpha-fetoprotein,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0001542//ovulation from ovarian follicle;GO:0042448//progesterone metabolic process;GO:0006810//transport;GO:0060395//SMAD protein signal transduction,GO:0046872//metal ion binding,K01883//Ribosome;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;DNA replication
1740,0,33,0,0,0,0,39,0,34,0,0,0,"DLG2;discs, large homolog 2 (Drosophila)",GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0044224//juxtaparanode region of axon,GO:0019233//sensory perception of pain;GO:0010923//negative regulation of phosphatase activity;GO:0007268//synaptic transmission;GO:0046939//nucleotide phosphorylation,GO:0004385//guanylate kinase activity;GO:0005515//protein binding,-
1741,0,22,0,20,46,45,0,0,58,1,1,359,"DLG3;discs, large homolog 3 (Drosophila)",GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0045202//synapse;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0005923//tight junction;GO:0005615//extracellular space,GO:0007268//synaptic transmission;GO:0008285//negative regulation of cell proliferation;GO:0007411//axon guidance;GO:0001736//establishment of planar polarity;GO:0010923//negative regulation of phosphatase activity;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity,GO:0030165//PDZ domain binding;GO:0019903//protein phosphatase binding;GO:0008022//protein C-terminus binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding;GO:0019902//phosphatase binding,-
1742,99,156,119,126,166,9,0,624,124,309,763,370,"DLG4;discs, large homolog 4 (Drosophila)",GO:0060076//excitatory synapse;GO:0030666//endocytic vesicle membrane;GO:0044309//neuron spine;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044306//neuron projection terminus;GO:0045202//synapse;GO:0097481//neuronal postsynaptic density;GO:0008021//synaptic vesicle;GO:0005737//cytoplasm;GO:0044300//cerebellar mossy fiber;GO:0043197//dendritic spine;GO:0008328//ionotropic glutamate receptor complex;GO:0014069//postsynaptic density;GO:0030863//cortical cytoskeleton;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0032839//dendrite cytoplasm;GO:0045211//postsynaptic membrane;GO:0005783//endoplasmic reticulum;GO:0044224//juxtaparanode region of axon,GO:0007612//learning;GO:0035418//protein localization to synapse;GO:0007411//axon guidance;GO:0050885//neuromuscular process controlling balance;GO:0060997//dendritic spine morphogenesis;GO:2000821//regulation of grooming behavior;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0050806//positive regulation of synaptic transmission;GO:0016188//synaptic vesicle maturation;GO:0035641//locomotory exploration behavior;GO:0071625//vocalization behavior;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006461//protein complex assembly;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0035176//social behavior;GO:0045184//establishment of protein localization;GO:0002091//negative regulation of receptor internalization;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0097113//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering;GO:0007165//signal transduction;GO:0097120//receptor localization to synapse,GO:0035255//ionotropic glutamate receptor binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0008022//protein C-terminus binding;GO:0097110//scaffold protein binding;GO:0031748//D1 dopamine receptor binding;GO:0031812//P2Y1 nucleotide receptor binding;GO:0033130//acetylcholine receptor binding;GO:0032403//protein complex binding;GO:0019903//protein phosphatase binding;GO:0031697//beta-1 adrenergic receptor binding,K11828//Huntington's disease;Glutamatergic synapse;Cocaine addiction
1743,2,1,0,6,13,0,81,0,21,59,0,236,DLST;dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex),GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005759//mitochondrial matrix;GO:0045252//oxoglutarate dehydrogenase complex;GO:0005634//nucleus,GO:0034641//cellular nitrogen compound metabolic process;GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0044281//small molecule metabolic process;GO:0006554//lysine catabolic process;GO:0006091//generation of precursor metabolites and energy,GO:0004149//dihydrolipoyllysine-residue succinyltransferase activity,"K00658//Citrate cycle (TCA cycle);Metabolic pathways;Microbial metabolism in diverse environments;Glycine, serine and threonine metabolism;Lysine degradation;Biosynthesis of secondary metabolites"
1745,0,0,0,0,0,13,34,26,11,0,7,0,DLX1;distal-less homeobox 1,GO:0005634//nucleus,GO:0045746//negative regulation of Notch signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021882//regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment;GO:0021544//subpallium development;GO:0021893//cerebral cortex GABAergic interneuron fate commitment;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0021766//hippocampus development;GO:0048706//embryonic skeletal system development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009954//proximal/distal pattern formation;GO:0043524//negative regulation of neuron apoptotic process,GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding,-
1746,66,0,0,0,0,0,0,126,18,0,22,0,DLX2;distal-less homeobox 2,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007420//brain development;GO:0045746//negative regulation of Notch signaling pathway;GO:0021893//cerebral cortex GABAergic interneuron fate commitment;GO:0021772//olfactory bulb development;GO:0021882//regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment;GO:0021544//subpallium development;GO:0051216//cartilage development;GO:0021766//hippocampus development;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0048755//branching morphogenesis of a nerve;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth,GO:0003727//single-stranded RNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding,-
1747,0,0,0,0,0,21,0,0,37,0,0,0,DLX3;distal-less homeobox 3,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth;GO:0071895//odontoblast differentiation;GO:0001890//placenta development;GO:0001568//blood vessel development,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
1748,0,0,0,0,0,0,27,0,0,0,0,0,DLX4;distal-less homeobox 4,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
1749,0,0,0,0,0,0,0,0,5,0,0,0,DLX5;distal-less homeobox 5,GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,"GO:0048646//anatomical structure formation involved in morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0060021//palate development;GO:0030509//BMP signaling pathway;GO:0007411//axon guidance;GO:0060325//face morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030326//embryonic limb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0071773//cellular response to BMP stimulus;GO:0001501//skeletal system development;GO:0007399//nervous system development;GO:0030855//epithelial cell differentiation;GO:0001958//endochondral ossification;GO:0001649//osteoblast differentiation;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0060166//olfactory pit development",GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0071837//HMG box domain binding,-
175,115,0,0,1,0,36,0,0,9,0,0,119,AGA;aspartylglucosaminidase,GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005764//lysosome,GO:0006508//proteolysis;GO:0051604//protein maturation;GO:0006517//protein deglycosylation,GO:0008233//peptidase activity;GO:0003948//N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity;GO:0043621//protein self-association,K01444//Other glycan degradation;Lysosome
1750,70,0,0,0,0,0,0,0,50,0,0,0,DLX6;distal-less homeobox 6,GO:0005634//nucleus,"GO:0030855//epithelial cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060021//palate development;GO:0007399//nervous system development;GO:0001501//skeletal system development;GO:0060322//head development;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0042472//inner ear morphogenesis;GO:0030326//embryonic limb morphogenesis",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
1755,0,0,85,4,5,0,0,20,143,69,0,19,DMBT1;deleted in malignant brain tumors 1,GO:0042589//zymogen granule membrane;GO:0005576//extracellular region;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0019898//extrinsic component of membrane;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space,GO:0030858//positive regulation of epithelial cell differentiation;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0043152//induction of bacterial agglutination;GO:0002221//pattern recognition receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0015031//protein transport;GO:0006898//receptor-mediated endocytosis;GO:0001833//inner cell mass cell proliferation,GO:0005515//protein binding;GO:0035375//zymogen binding;GO:0008329//signaling pattern recognition receptor activity;GO:0048306//calcium-dependent protein binding;GO:0005044//scavenger receptor activity,K13912//Salivary secretion
1756,78,0,0,0,24,26,23,0,176,0,0,0,DMD;dystrophin,GO:0005634//nucleus;GO:0016013//syntrophin complex;GO:0030175//filopodium;GO:0016010//dystrophin-associated glycoprotein complex;GO:0031527//filopodium membrane;GO:0009986//cell surface;GO:0005856//cytoskeleton;GO:0016328//lateral plasma membrane;GO:0042383//sarcolemma;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0043034//costamere;GO:0045211//postsynaptic membrane;GO:0043234//protein complex,GO:0010976//positive regulation of neuron projection development;GO:0045666//positive regulation of neuron differentiation;GO:0030049//muscle filament sliding;GO:0043623//cellular protein complex assembly;GO:0043043//peptide biosynthetic process;GO:0007517//muscle organ development;GO:1901385//regulation of voltage-gated calcium channel activity;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:0090287//regulation of cellular response to growth factor stimulus;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0002027//regulation of heart rate;GO:0034613//cellular protein localization;GO:0014819//regulation of skeletal muscle contraction;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0030198//extracellular matrix organization;GO:0060048//cardiac muscle contraction;GO:0086001//cardiac muscle cell action potential;GO:0044458//motile cilium assembly,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0050998//nitric-oxide synthase binding;GO:0003779//actin binding;GO:0017166//vinculin binding;GO:0005200//structural constituent of cytoskeleton;GO:0008307//structural constituent of muscle;GO:0002162//dystroglycan binding;GO:0017022//myosin binding,K10366//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Viral myocarditis;Dilated cardiomyopathy
1757,42,30,0,0,0,0,53,58,15,0,8,0,SARDH;sarcosine dehydrogenase,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006546//glycine catabolic process;GO:0055114//oxidation-reduction process;GO:0032259//methylation,GO:0004047//aminomethyltransferase activity;GO:0008480//sarcosine dehydrogenase activity,"K00314//Glycine, serine and threonine metabolism;Metabolic pathways"
1758,78,0,0,0,0,0,0,0,7,0,0,0,DMP1;dentin matrix acidic phosphoprotein 1,GO:0005576//extracellular region;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0031214//biomineral tissue development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0001503//ossification,GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0050840//extracellular matrix binding,-
1759,1,0,0,0,0,13,22,87,48,0,0,0,DNM1;dynamin 1,GO:0070062//extracellular vesicular exosome;GO:0030117//membrane coat;GO:0005874//microtubule,GO:0006897//endocytosis;GO:0006184//GTP catabolic process;GO:0006898//receptor-mediated endocytosis;GO:0007032//endosome organization;GO:0031623//receptor internalization,GO:0003924//GTPase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005525//GTP binding;GO:0032403//protein complex binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding,K01528//Endocytosis;Bacterial invasion of epithelial cells;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
176,0,1,0,0,0,20,8,3,116,281,12,0,ACAN;aggrecan,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0005796//Golgi lumen;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0042340//keratan sulfate catabolic process;GO:0007155//cell adhesion;GO:0001501//skeletal system development;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0005975//carbohydrate metabolic process,GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent,-
1760,149,0,0,15,15,15,0,33,9,0,57,0,DMPK;dystrophia myotonica-protein kinase,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005640//nuclear outer membrane;GO:0031307//integral component of mitochondrial outer membrane,GO:0014853//regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction;GO:0014722//regulation of skeletal muscle contraction by calcium ion signaling;GO:0050790//regulation of catalytic activity;GO:0006874//cellular calcium ion homeostasis;GO:0010830//regulation of myotube differentiation;GO:0010657//muscle cell apoptotic process;GO:0051823//regulation of synapse structural plasticity;GO:0006468//protein phosphorylation;GO:0002028//regulation of sodium ion transport;GO:0008016//regulation of heart contraction;GO:0006998//nuclear envelope organization,GO:0005524//ATP binding;GO:0031072//heat shock protein binding;GO:0017020//myosin phosphatase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
1762,44,0,0,0,0,6,0,1,19,0,10,0,"DMWD;dystrophia myotonica, WD repeat containing",-,-,-,K12602//RNA degradation
1763,0,0,0,0,7,1,43,0,22,0,10,532,DNA2;DNA replication helicase/nuclease 2,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005760//gamma DNA polymerase complex;GO:0042645//mitochondrial nucleoid,"GO:0032508//DNA duplex unwinding;GO:0000723//telomere maintenance;GO:0043137//DNA replication, removal of RNA primer;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000722//telomere maintenance via recombination;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000737//DNA catabolic process, endonucleolytic;GO:0045740//positive regulation of DNA replication;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006200//ATP catabolic process;GO:0006264//mitochondrial DNA replication;GO:0000076//DNA replication checkpoint;GO:0043504//mitochondrial DNA repair;GO:0000729//DNA double-strand break processing;GO:0006284//base-excision repair","GO:0005524//ATP binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016890//site-specific endodeoxyribonuclease activity, specific for altered base;GO:0016887//ATPase activity;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0043142//single-stranded DNA-dependent ATPase activity;GO:0043139//5'-3' DNA helicase activity;GO:0003678//DNA helicase activity;GO:0004518//nuclease activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0017108//5'-flap endonuclease activity",K10742//DNA replication
1767,65,5,0,6,77,78,31,94,293,250,8,0,"DNAH5;dynein, axonemal, heavy chain 5",GO:0005858//axonemal dynein complex;GO:0005930//axoneme;GO:0005874//microtubule,GO:0021670//lateral ventricle development;GO:0006200//ATP catabolic process;GO:0003341//cilium movement;GO:0070986//left/right axis specification,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity,K10408//Huntington's disease
1768,100,28,20,3,5,124,67,0,290,336,20,327,"DNAH6;dynein, axonemal, heavy chain 6",GO:0005874//microtubule;GO:0005858//axonemal dynein complex,GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0001539//cilium or flagellum-dependent cell motility,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,K10408//Huntington's disease
1769,0,52,2,75,313,78,35,1,177,17,38,0,"DNAH8;dynein, axonemal, heavy chain 8",GO:0005858//axonemal dynein complex;GO:0005874//microtubule,GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0001539//cilium or flagellum-dependent cell motility;GO:0007018//microtubule-based movement,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,K10408//Huntington's disease
1770,170,31,88,3,20,96,101,0,179,89,22,0,"DNAH9;dynein, axonemal, heavy chain 9",GO:0005930//axoneme;GO:0030286//dynein complex;GO:0005856//cytoskeleton;GO:0005874//microtubule,GO:0007018//microtubule-based movement;GO:0006928//cellular component movement;GO:0007283//spermatogenesis;GO:0006200//ATP catabolic process;GO:0030030//cell projection organization;GO:0008152//metabolic process,GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0005524//ATP binding,K10408//Huntington's disease
1773,0,29,50,37,18,0,0,0,26,0,15,0,DNASE1;deoxyribonuclease I,GO:0005635//nuclear envelope;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0006915//apoptotic process;GO:0000737//DNA catabolic process, endonucleolytic",GO:0003779//actin binding;GO:0005515//protein binding;GO:0004530//deoxyribonuclease I activity,-
1774,0,1,0,16,33,16,17,0,39,0,0,0,DNASE1L1;deoxyribonuclease I-like 1,GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,"GO:0006259//DNA metabolic process;GO:0000737//DNA catabolic process, endonucleolytic","GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0003677//DNA binding;GO:0004536//deoxyribonuclease activity",-
1775,0,0,0,0,0,0,0,0,19,0,0,0,DNASE1L2;deoxyribonuclease I-like 2,GO:0005576//extracellular region;GO:0005737//cytoplasm,"GO:0006259//DNA metabolic process;GO:0000737//DNA catabolic process, endonucleolytic;GO:0001942//hair follicle development","GO:0003677//DNA binding;GO:0004536//deoxyribonuclease activity;GO:0005509//calcium ion binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters",-
1776,90,0,0,0,0,11,0,0,0,0,0,0,DNASE1L3;deoxyribonuclease I-like 3,GO:0005634//nucleus,GO:0010623//developmental programmed cell death;GO:0006259//DNA metabolic process;GO:0006309//apoptotic DNA fragmentation,"GO:0005509//calcium ion binding;GO:0004536//deoxyribonuclease activity;GO:0003677//DNA binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters",-
1777,0,0,0,0,0,0,0,0,14,130,0,0,"DNASE2;deoxyribonuclease II, lysosomal",GO:0005764//lysosome;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome,GO:0006259//DNA metabolic process;GO:0006309//apoptotic DNA fragmentation;GO:0030218//erythrocyte differentiation,GO:0003677//DNA binding;GO:0004531//deoxyribonuclease II activity,K01158//Lysosome
1778,104,213,13,42,238,32,34,54,83,228,5,0,"DYNC1H1;dynein, cytoplasmic 1, heavy chain 1",GO:0005874//microtubule;GO:0005813//centrosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005868//cytoplasmic dynein complex;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006810//transport;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0034063//stress granule assembly;GO:0007052//mitotic spindle organization;GO:0007018//microtubule-based movement;GO:0008219//cell death;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003777//microtubule motor activity,K10413//Salmonella infection;Vasopressin-regulated water reabsorption;Phagosome
178,6,95,1,36,151,28,20,0,76,0,3,0,"AGL;amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase",GO:0005730//nucleolus;GO:0016529//sarcoplasmic reticulum;GO:0005829//cytosol;GO:0016234//inclusion body;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043033//isoamylase complex,GO:0051384//response to glucocorticoid;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005980//glycogen catabolic process;GO:0005978//glycogen biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0007584//response to nutrient,"GO:0030247//polysaccharide binding;GO:0004135//amylo-alpha-1,6-glucosidase activity;GO:0005515//protein binding;GO:0004134//4-alpha-glucanotransferase activity;GO:0031593//polyubiquitin binding",K01196//Metabolic pathways;Starch and sucrose metabolism
1780,96,0,0,0,0,0,0,58,63,0,0,0,"DYNC1I1;dynein, cytoplasmic 1, intermediate chain 1",GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005868//cytoplasmic dynein complex;GO:0031982//vesicle;GO:0005829//cytosol;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0048471//perinuclear region of cytoplasm,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0047496//vesicle transport along microtubule;GO:0008152//metabolic process,GO:0030507//spectrin binding;GO:0003774//motor activity;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003777//microtubule motor activity,K10415//Vasopressin-regulated water reabsorption;Phagosome;Salmonella infection
1781,0,1,0,22,120,23,0,0,75,0,8,0,"DYNC1I2;dynein, cytoplasmic 1, intermediate chain 2",GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005868//cytoplasmic dynein complex,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0008152//metabolic process;GO:0016032//viral process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0006810//transport,GO:0003777//microtubule motor activity,K10415//Salmonella infection;Vasopressin-regulated water reabsorption;Phagosome
1783,137,112,1,135,716,5,0,0,9,13,9,1,"DYNC1LI2;dynein, cytoplasmic 1, light intermediate chain 2",GO:0016020//membrane;GO:0005829//cytosol;GO:0005868//cytoplasmic dynein complex;GO:0005874//microtubule;GO:0005813//centrosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0006810//transport;GO:0000226//microtubule cytoskeleton organization;GO:0008152//metabolic process;GO:0051642//centrosome localization,GO:0005524//ATP binding;GO:0003777//microtubule motor activity,K10416//Vasopressin-regulated water reabsorption;Phagosome;Salmonella infection
1785,0,48,1,4,31,0,47,4,45,0,6,0,DNM2;dynamin 2,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0045211//postsynaptic membrane;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0005925//focal adhesion;GO:0030666//endocytic vesicle membrane;GO:0030496//midbody;GO:0005829//cytosol;GO:0005874//microtubule,"GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050999//regulation of nitric-oxide synthase activity;GO:0006897//endocytosis;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0061024//membrane organization;GO:0007165//signal transduction;GO:0031623//receptor internalization;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006184//GTP catabolic process;GO:0046209//nitric oxide metabolic process;GO:0048489//synaptic vesicle transport;GO:0008219//cell death;GO:0033572//transferrin transport;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process",GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0019899//enzyme binding;GO:0005525//GTP binding,K01528//Bacterial invasion of epithelial cells;Endocytosis;Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis
1786,0,98,36,15,21,0,20,0,77,30,27,0,DNMT1;DNA (cytosine-5-)-methyltransferase 1,GO:0005657//replication fork;GO:0005634//nucleus;GO:0005721//pericentric heterochromatin,"GO:0006351//transcription, DNA-templated;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0090116//C-5 methylation of cytosine;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0010628//positive regulation of gene expression;GO:0042127//regulation of cell proliferation;GO:0071230//cellular response to amino acid stimulus;GO:0010216//maintenance of DNA methylation;GO:0006306//DNA methylation;GO:0016568//chromatin modification;GO:0016458//gene silencing",GO:0003723//RNA binding;GO:0003682//chromatin binding;GO:0009008//DNA-methyltransferase activity;GO:0003677//DNA binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0008134//transcription factor binding;GO:0005515//protein binding,K00558//Cysteine and methionine metabolism;Folate biosynthesis;Metabolic pathways
1787,0,0,0,23,29,0,39,0,13,0,20,0,TRDMT1;tRNA aspartic acid methyltransferase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0090116//C-5 methylation of cytosine;GO:0030488//tRNA methylation;GO:0001975//response to amphetamine,GO:0008175//tRNA methyltransferase activity;GO:0003677//DNA binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0003723//RNA binding,-
1788,33,0,0,10,30,17,16,12,46,29,12,0,DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha,"GO:0005737//cytoplasm;GO:0000791//euchromatin;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005730//nucleolus;GO:0005720//nuclear heterochromatin",GO:0006349//regulation of gene expression by genetic imprinting;GO:0071230//cellular response to amino acid stimulus;GO:0046498//S-adenosylhomocysteine metabolic process;GO:0006306//DNA methylation;GO:0043046//DNA methylation involved in gamete generation;GO:0006346//methylation-dependent chromatin silencing;GO:0090116//C-5 methylation of cytosine;GO:0010424//DNA methylation on cytosine within a CG sequence;GO:0044027//hypermethylation of CpG island;GO:0046499//S-adenosylmethioninamine metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0043045//DNA methylation involved in embryo development,"GO:0051718//DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates;GO:0003682//chromatin binding;GO:0042802//identical protein binding;GO:0045322//unmethylated CpG binding;GO:0003677//DNA binding;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding",K00558//Metabolic pathways;Folate biosynthesis;Cysteine and methionine metabolism
1789,246,0,0,0,0,1,18,10,36,1,7,1,DNMT3B;DNA (cytosine-5-)-methyltransferase 3 beta,"GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005720//nuclear heterochromatin",GO:0042493//response to drug;GO:0046498//S-adenosylhomocysteine metabolic process;GO:0071230//cellular response to amino acid stimulus;GO:0006349//regulation of gene expression by genetic imprinting;GO:0010212//response to ionizing radiation;GO:0006346//methylation-dependent chromatin silencing;GO:0043045//DNA methylation involved in embryo development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:0045666//positive regulation of neuron differentiation;GO:0006306//DNA methylation;GO:0010424//DNA methylation on cytosine within a CG sequence;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0090116//C-5 methylation of cytosine;GO:0046499//S-adenosylmethioninamine metabolic process;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0031503//protein complex localization,"GO:0003714//transcription corepressor activity;GO:0009008//DNA-methyltransferase activity;GO:0051718//DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates;GO:0003886//DNA (cytosine-5-)-methyltransferase activity;GO:0046872//metal ion binding;GO:0045322//unmethylated CpG binding;GO:0005515//protein binding",K00558//Metabolic pathways;Folate biosynthesis;Cysteine and methionine metabolism
1791,0,0,0,0,0,0,0,0,53,0,0,0,DNTT;DNA nucleotidylexotransferase,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006261//DNA-dependent DNA replication;GO:0071897//DNA biosynthetic process;GO:0006304//DNA modification,GO:0046872//metal ion binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003912//DNA nucleotidylexotransferase activity;GO:0003677//DNA binding,K00977//Non-homologous end-joining;Hematopoietic cell lineage
1793,0,1,0,12,142,16,46,0,62,39,0,0,DOCK1;dedicator of cytokinesis 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006911//phagocytosis, engulfment;GO:0006915//apoptotic process;GO:0007596//blood coagulation;GO:0007411//axon guidance;GO:0007264//small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0016477//cell migration;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043547//positive regulation of GTPase activity;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis",GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0017124//SH3 domain binding;GO:0005515//protein binding,K13708//Focal adhesion;Shigellosis;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells
1794,0,0,0,0,0,47,24,16,68,0,0,0,DOCK2;dedicator of cytokinesis 2,GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0045059//positive thymic T cell selection;GO:0050766//positive regulation of phagocytosis;GO:0001768//establishment of T cell polarity;GO:0002277//myeloid dendritic cell activation involved in immune response;GO:0016032//viral process;GO:0007264//small GTPase mediated signal transduction;GO:0045060//negative thymic T cell selection;GO:0001766//membrane raft polarization;GO:0050690//regulation of defense response to virus by virus;GO:0044351//macropinocytosis;GO:0032855//positive regulation of Rac GTPase activity;GO:0006935//chemotaxis;GO:0001771//immunological synapse formation;GO:0046633//alpha-beta T cell proliferation;GO:0030036//actin cytoskeleton organization,GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042608//T cell receptor binding;GO:0030675//Rac GTPase activator activity,K12367//Chemokine signaling pathway;Fc gamma R-mediated phagocytosis
1795,258,0,0,2,11,27,9,0,121,0,17,172,DOCK3;dedicator of cytokinesis 3,GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017124//SH3 domain binding;GO:0005515//protein binding,-
1796,0,0,0,0,6,46,0,0,30,0,15,0,"DOK1;docking protein 1, 62kDa (downstream of tyrosine kinase 1)",GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0007165//signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007166//cell surface receptor signaling pathway,GO:0005158//insulin receptor binding;GO:0005057//receptor signaling protein activity;GO:0005515//protein binding,K14752//Measles
1798,0,0,25,4,29,0,0,0,0,125,18,0,DPAGT1;dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase),GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0019408//dolichol biosynthetic process;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0051259//protein oligomerization;GO:0006487//protein N-linked glycosylation;GO:0044267//cellular protein metabolic process,"GO:0003975//UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0008963//phospho-N-acetylmuramoyl-pentapeptide-transferase activity",K01001//N-Glycan biosynthesis;Metabolic pathways
18,40,55,1,66,195,0,0,0,35,0,26,0,ABAT;4-aminobutyrate aminotransferase,GO:0070062//extracellular vesicular exosome;GO:0032144//4-aminobutyrate transaminase complex;GO:0005739//mitochondrion;GO:0043005//neuron projection;GO:0005759//mitochondrial matrix,GO:0042493//response to drug;GO:0007626//locomotory behavior;GO:0048148//behavioral response to cocaine;GO:0010039//response to iron ion;GO:0035094//response to nicotine;GO:0007620//copulation;GO:0045776//negative regulation of blood pressure;GO:0001666//response to hypoxia;GO:0009450//gamma-aminobutyric acid catabolic process;GO:0045471//response to ethanol;GO:0007269//neurotransmitter secretion;GO:0042135//neurotransmitter catabolic process;GO:0007268//synaptic transmission,GO:0042803//protein homodimerization activity;GO:0032145//succinate-semialdehyde dehydrogenase binding;GO:0003867//4-aminobutyrate transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0047298//(S)-3-amino-2-methylpropionate transaminase activity,"K13524//Metabolic pathways;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Alanine, aspartate and glutamate metabolism;Butanoate metabolism;Propanoate metabolism;GABAergic synapse"
1800,0,0,0,0,0,0,43,0,27,0,0,0,DPEP1;dipeptidase 1 (renal),GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0045177//apical part of cell;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031528//microvillus membrane;GO:0005615//extracellular space,GO:0006749//glutathione metabolic process;GO:0035690//cellular response to drug;GO:0016999//antibiotic metabolic process;GO:0050667//homocysteine metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0030336//negative regulation of cell migration;GO:0072340//cellular lactam catabolic process;GO:0006508//proteolysis;GO:0043066//negative regulation of apoptotic process;GO:0071732//cellular response to nitric oxide;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071277//cellular response to calcium ion;GO:0006691//leukotriene metabolic process;GO:0044281//small molecule metabolic process,GO:0070573//metallodipeptidase activity;GO:0034235//GPI anchor binding;GO:0008235//metalloexopeptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0072341//modified amino acid binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
1801,0,0,0,0,11,10,31,24,38,0,21,626,DPH1;diphthamide biosynthesis 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008283//cell proliferation;GO:0006412//translation;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine,-,-
1802,0,0,0,5,0,0,28,0,0,0,0,0,DPH2;DPH2 homolog (S. cerevisiae),GO:0005737//cytoplasm,GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine,-,-
1803,0,219,29,120,404,48,22,71,68,1,194,0,DPP4;dipeptidyl-peptidase 4,GO:0046581//intercellular canaliculus;GO:0030139//endocytic vesicle;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0071438//invadopodium membrane;GO:0045121//membrane raft;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane,GO:0007155//cell adhesion;GO:0006508//proteolysis;GO:0042110//T cell activation;GO:0001666//response to hypoxia;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0043542//endothelial cell migration;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0031295//T cell costimulation,GO:0008236//serine-type peptidase activity;GO:0042802//identical protein binding;GO:0002020//protease binding;GO:0008239//dipeptidyl-peptidase activity;GO:0005102//receptor binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K01278//Protein digestion and absorption
1804,90,0,0,0,0,0,20,68,143,0,10,0,DPP6;dipeptidyl-peptidase 6,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0008219//cell death;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0006508//proteolysis,GO:0008239//dipeptidyl-peptidase activity;GO:0008236//serine-type peptidase activity,K01278//Protein digestion and absorption
1805,9,0,0,0,0,48,0,60,24,0,1,0,DPT;dermatopontin,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0007155//cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0030199//collagen fibril organization,-,-
1806,0,0,0,4,28,0,0,0,8,0,0,0,DPYD;dihydropyrimidine dehydrogenase,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006212//uracil catabolic process;GO:0019483//beta-alanine biosynthetic process;GO:0006214//thymidine catabolic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0055114//oxidation-reduction process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0044281//small molecule metabolic process;GO:0006210//thymine catabolic process;GO:0006145//purine nucleobase catabolic process;GO:0006208//pyrimidine nucleobase catabolic process;GO:0006222//UMP biosynthetic process,"GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0017113//dihydropyrimidine dehydrogenase (NADP+) activity",K00207//Drug metabolism - other enzymes;Pyrimidine metabolism;Pantothenate and CoA biosynthesis;Metabolic pathways;beta-Alanine metabolism
1807,0,51,0,25,31,0,24,0,9,0,0,0,DPYS;dihydropyrimidinase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006208//pyrimidine nucleobase catabolic process;GO:0051289//protein homotetramerization;GO:0006210//thymine catabolic process;GO:0019482//beta-alanine metabolic process;GO:0044281//small molecule metabolic process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006212//uracil catabolic process,GO:0051219//phosphoprotein binding;GO:0008270//zinc ion binding;GO:0002058//uracil binding;GO:0016597//amino acid binding;GO:0002059//thymine binding;GO:0004157//dihydropyrimidinase activity,K01464//Pantothenate and CoA biosynthesis;Pyrimidine metabolism;Drug metabolism - other enzymes;beta-Alanine metabolism;Metabolic pathways
1808,28,0,0,0,0,7,40,1,24,138,0,0,DPYSL2;dihydropyrimidinase-like 2,GO:0005874//microtubule;GO:0030424//axon;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0007399//nervous system development;GO:0007010//cytoskeleton organization;GO:0048489//synaptic vesicle transport;GO:0007411//axon guidance;GO:0006139//nucleobase-containing compound metabolic process;GO:0006897//endocytosis;GO:0021772//olfactory bulb development;GO:0042220//response to cocaine;GO:0014049//positive regulation of glutamate secretion;GO:0007165//signal transduction;GO:0006208//pyrimidine nucleobase catabolic process;GO:0042493//response to drug;GO:0021510//spinal cord development;GO:0045664//regulation of neuron differentiation;GO:0001975//response to amphetamine,GO:0004157//dihydropyrimidinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,K07528//Axon guidance
1809,0,28,0,61,160,34,14,68,38,0,24,3,DPYSL3;dihydropyrimidinase-like 3,GO:0070382//exocytic vesicle;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0044297//cell body;GO:0031941//filamentous actin;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0048678//response to axon injury;GO:0030336//negative regulation of cell migration;GO:0007411//axon guidance;GO:0051764//actin crosslink formation;GO:0051017//actin filament bundle assembly;GO:0010976//positive regulation of neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0006208//pyrimidine nucleobase catabolic process;GO:0051491//positive regulation of filopodium assembly;GO:0071345//cellular response to cytokine stimulus;GO:0051260//protein homooligomerization,"GO:0035374//chondroitin sulfate binding;GO:0051219//phosphoprotein binding;GO:0017124//SH3 domain binding;GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides",K07528//Axon guidance
181,0,0,0,0,0,10,19,0,10,0,0,0,AGRP;agouti related protein homolog (mouse),GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0043025//neuronal cell body,GO:0007631//feeding behavior;GO:0007218//neuropeptide signaling pathway;GO:0060135//maternal process involved in female pregnancy;GO:0008343//adult feeding behavior;GO:0042755//eating behavior;GO:0032868//response to insulin;GO:0009755//hormone-mediated signaling pathway;GO:2000253//positive regulation of feeding behavior;GO:0009648//photoperiodism;GO:0060259//regulation of feeding behavior,GO:0005184//neuropeptide hormone activity;GO:0005102//receptor binding,K05231//Adipocytokine signaling pathway
1810,0,0,1,25,96,0,0,0,8,0,0,0,"DR1;down-regulator of transcription 1, TBP-binding (negative cofactor 2)",GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,"GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0017025//TBP-class protein binding;GO:0003714//transcription corepressor activity,K08065//Tuberculosis;Antigen processing and presentation;HTLV-I infection;K02326//HTLV-I infection;Metabolic pathways;Nucleotide excision repair;DNA replication;Purine metabolism;Base excision repair;Pyrimidine metabolism
1811,0,0,27,4,0,19,0,0,64,0,6,0,"SLC26A3;solute carrier family 26 (anion exchanger), member 3",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0097225//sperm midpiece;GO:0016324//apical plasma membrane,"GO:0006811//ion transport;GO:0048240//sperm capacitation;GO:0006820//anion transport;GO:1902358//sulfate transmembrane transport;GO:0007588//excretion;GO:0071320//cellular response to cAMP;GO:2001141//regulation of RNA biosynthetic process;GO:0015701//bicarbonate transport;GO:0051454//intracellular pH elevation;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0060081//membrane hyperpolarization;GO:0006355//regulation of transcription, DNA-templated",GO:0015301//anion:anion antiporter activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0015108//chloride transmembrane transporter activity;GO:0005215//transporter activity;GO:0003712//transcription cofactor activity;GO:0008271//secondary active sulfate transmembrane transporter activity,K14078//Mineral absorption;Pancreatic secretion
1812,201,0,0,0,0,0,0,0,26,32,5,0,DRD1;dopamine receptor D1,GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane,"GO:0001975//response to amphetamine;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0035106//operant conditioning;GO:0021542//dentate gyrus development;GO:0001662//behavioral fear response;GO:0046960//sensitization;GO:0014002//astrocyte development;GO:0007617//mating behavior;GO:0021756//striatum development;GO:0046959//habituation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0042493//response to drug;GO:0001963//synaptic transmission, dopaminergic;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0001661//conditioned taste aversion;GO:0007190//activation of adenylate cyclase activity;GO:0030335//positive regulation of cell migration;GO:0007628//adult walking behavior;GO:0001659//temperature homeostasis;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0008542//visual learning;GO:0007416//synapse assembly;GO:0007625//grooming behavior;GO:0006606//protein import into nucleus;GO:0007613//memory;GO:0071870//cellular response to catecholamine stimulus;GO:0042311//vasodilation;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0042053//regulation of dopamine metabolic process;GO:0060291//long-term synaptic potentiation;GO:0060292//long term synaptic depression;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0043268//positive regulation of potassium ion transport;GO:0042711//maternal behavior;GO:0015872//dopamine transport;GO:0048148//behavioral response to cocaine;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0019226//transmission of nerve impulse;GO:0042417//dopamine metabolic process;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0060134//prepulse inhibition;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0046323//glucose import;GO:0030432//peristalsis;GO:0019228//neuronal action potential","GO:0035240//dopamine binding;GO:0005515//protein binding;GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs",K04144//Morphine addiction;Amphetamine addiction;Gap junction;Cocaine addiction;Dopaminergic synapse;Neuroactive ligand-receptor interaction;Calcium signaling pathway;Alcoholism
1813,0,0,21,0,0,0,0,0,6,0,0,0,DRD2;dopamine receptor D2,GO:0030424//axon;GO:0043204//perikaryon;GO:0001669//acrosomal vesicle;GO:0030139//endocytic vesicle;GO:0005887//integral component of plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0036126//sperm flagellum;GO:0043197//dendritic spine;GO:0043679//axon terminus;GO:0014069//postsynaptic density;GO:0016328//lateral plasma membrane,"GO:0008104//protein localization;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0007628//adult walking behavior;GO:0007194//negative regulation of adenylate cyclase activity;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0032922//circadian regulation of gene expression;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0043473//pigmentation;GO:0010039//response to iron ion;GO:0021769//orbitofrontal cortex development;GO:0043266//regulation of potassium ion transport;GO:0048755//branching morphogenesis of a nerve;GO:0001963//synaptic transmission, dopaminergic;GO:0002027//regulation of heart rate;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0050709//negative regulation of protein secretion;GO:0050482//arachidonic acid secretion;GO:0043278//response to morphine;GO:0009416//response to light stimulus;GO:0031223//auditory behavior;GO:0008285//negative regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0002052//positive regulation of neuroblast proliferation;GO:0042417//dopamine metabolic process;GO:1900273//positive regulation of long-term synaptic potentiation;GO:0035815//positive regulation of renal sodium excretion;GO:0051209//release of sequestered calcium ion into cytosol;GO:0042220//response to cocaine;GO:0009636//response to toxic substance;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0060124//positive regulation of growth hormone secretion;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0007626//locomotory behavior;GO:0042321//negative regulation of circadian sleep/wake cycle, sleep;GO:0034776//response to histamine;GO:0046488//phosphatidylinositol metabolic process;GO:0048678//response to axon injury;GO:0046676//negative regulation of insulin secretion;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0035094//response to nicotine;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0007416//synapse assembly;GO:0007625//grooming behavior;GO:0021984//adenohypophysis development;GO:0001659//temperature homeostasis;GO:0007270//neuron-neuron synaptic transmission;GO:0035810//positive regulation of urine volume;GO:0030814//regulation of cAMP metabolic process;GO:0007409//axonogenesis;GO:0006874//cellular calcium ion homeostasis;GO:0042493//response to drug;GO:0002092//positive regulation of receptor internalization;GO:0001666//response to hypoxia;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0021756//striatum development;GO:0045776//negative regulation of blood pressure;GO:0001975//response to amphetamine;GO:0090325//regulation of locomotion involved in locomotory behavior;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0033602//negative regulation of dopamine secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032467//positive regulation of cytokinesis;GO:0007616//long-term memory;GO:0008306//associative learning;GO:0030432//peristalsis;GO:0030336//negative regulation of cell migration;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0032147//activation of protein kinase activity;GO:0007608//sensory perception of smell;GO:0048149//behavioral response to ethanol;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0060134//prepulse inhibition;GO:0002028//regulation of sodium ion transport;GO:0048148//behavioral response to cocaine;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0002031//G-protein coupled receptor internalization;GO:0014854//response to inactivity;GO:0051823//regulation of synapse structural plasticity;GO:0007631//feeding behavior;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0016055//Wnt signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:0008542//visual learning;GO:0040018//positive regulation of multicellular organism growth","GO:0015459//potassium channel regulator activity;GO:0042802//identical protein binding;GO:0035240//dopamine binding;GO:0008144//drug binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding;GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go",K04145//Alcoholism;Neuroactive ligand-receptor interaction;Gap junction;Cocaine addiction;Dopaminergic synapse
1814,0,0,0,0,0,0,0,0,49,0,0,0,DRD3;dopamine receptor D3,GO:0005886//plasma membrane;GO:0030139//endocytic vesicle;GO:0042995//cell projection;GO:0045177//apical part of cell;GO:0005887//integral component of plasma membrane,"GO:0007612//learning;GO:0045471//response to ethanol;GO:0007186//G-protein coupled receptor signaling pathway;GO:0019216//regulation of lipid metabolic process;GO:0035483//gastric emptying;GO:0014059//regulation of dopamine secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007611//learning or memory;GO:0030814//regulation of cAMP metabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0042493//response to drug;GO:0001963//synaptic transmission, dopaminergic;GO:0050709//negative regulation of protein secretion;GO:0045776//negative regulation of blood pressure;GO:0050482//arachidonic acid secretion;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0001975//response to amphetamine;GO:0090325//regulation of locomotion involved in locomotory behavior;GO:0043278//response to morphine;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032467//positive regulation of cytokinesis;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0002016//regulation of blood volume by renin-angiotensin;GO:0042417//dopamine metabolic process;GO:0035815//positive regulation of renal sodium excretion;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0060134//prepulse inhibition;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0042220//response to cocaine;GO:0048148//behavioral response to cocaine;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0034776//response to histamine;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell proliferation;GO:0002031//G-protein coupled receptor internalization;GO:0050883//musculoskeletal movement, spinal reflex action;GO:0045840//positive regulation of mitosis;GO:0035176//social behavior;GO:0046717//acid secretion;GO:0051898//negative regulation of protein kinase B signaling;GO:0040014//regulation of multicellular organism growth;GO:0008542//visual learning;GO:0045187//regulation of circadian sleep/wake cycle, sleep","GO:0005515//protein binding;GO:0035240//dopamine binding;GO:0019904//protein domain specific binding;GO:0008144//drug binding;GO:0031748//D1 dopamine receptor binding;GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go",K04146//Neuroactive ligand-receptor interaction;Dopaminergic synapse
1815,0,0,0,0,7,0,0,0,0,0,0,0,DRD4;dopamine receptor D4,GO:0005887//integral component of plasma membrane;GO:0043195//terminal bouton;GO:0012506//vesicle membrane;GO:0043197//dendritic spine;GO:0005938//cell cortex;GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0005886//plasma membrane,"GO:0007194//negative regulation of adenylate cyclase activity;GO:0000187//activation of MAPK activity;GO:0050848//regulation of calcium-mediated signaling;GO:0007212//dopamine receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0046928//regulation of neurotransmitter secretion;GO:0001963//synaptic transmission, dopaminergic;GO:0050709//negative regulation of protein secretion;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0007614//short-term memory;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0050482//arachidonic acid secretion;GO:0001662//behavioral fear response;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0009648//photoperiodism;GO:0001975//response to amphetamine;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0042417//dopamine metabolic process;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0048149//behavioral response to ethanol;GO:0042596//fear response;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0048148//behavioral response to cocaine;GO:0060406//positive regulation of penile erection;GO:0034776//response to histamine;GO:0007623//circadian rhythm;GO:0048545//response to steroid hormone;GO:0035176//social behavior;GO:0042752//regulation of circadian rhythm;GO:0042053//regulation of dopamine metabolic process;GO:0033674//positive regulation of kinase activity;GO:0008355//olfactory learning;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0060041//retina development in camera-type eye;GO:0008344//adult locomotory behavior","GO:0001591//dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0008144//drug binding;GO:0017124//SH3 domain binding;GO:0035240//dopamine binding;GO:0042802//identical protein binding;GO:0015459//potassium channel regulator activity;GO:0005515//protein binding",K04147//Neuroactive ligand-receptor interaction;Dopaminergic synapse
1816,0,0,0,0,0,10,0,0,9,0,0,0,DRD5;dopamine receptor D5,GO:0005887//integral component of plasma membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane,"GO:0042060//wound healing;GO:0019226//transmission of nerve impulse;GO:0007190//activation of adenylate cyclase activity;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0045762//positive regulation of adenylate cyclase activity;GO:0008306//associative learning;GO:0006874//cellular calcium ion homeostasis;GO:0001963//synaptic transmission, dopaminergic;GO:0072593//reactive oxygen species metabolic process;GO:0045924//regulation of female receptivity;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0042220//response to cocaine;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0060292//long term synaptic depression;GO:0001994//norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0001975//response to amphetamine;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0045776//negative regulation of blood pressure;GO:0046960//sensitization;GO:0071870//cellular response to catecholamine stimulus;GO:0001992//regulation of systemic arterial blood pressure by vasopressin","GO:0001588//dopamine neurotransmitter receptor activity, coupled via Gs;GO:0035240//dopamine binding",K05840//Dopaminergic synapse;Neuroactive ligand-receptor interaction;Calcium signaling pathway
1819,52,0,0,0,2,0,0,58,9,0,0,0,DRG2;developmentally regulated GTP binding protein 2,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0007165//signal transduction,GO:0005525//GTP binding,-
182,9,0,0,0,12,10,14,0,66,76,0,255,JAG1;jagged 1,GO:0016020//membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell,GO:0061156//pulmonary artery morphogenesis;GO:0032495//response to muramyl dipeptide;GO:0061444//endocardial cushion cell development;GO:0030097//hemopoiesis;GO:0001709//cell fate determination;GO:0030334//regulation of cell migration;GO:0035909//aorta morphogenesis;GO:0042127//regulation of cell proliferation;GO:0003215//cardiac right ventricle morphogenesis;GO:0097150//neuronal stem cell maintenance;GO:0002011//morphogenesis of an epithelial sheet;GO:0061073//ciliary body morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0002456//T cell mediated immunity;GO:0001525//angiogenesis;GO:0061314//Notch signaling involved in heart development;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:2000737//negative regulation of stem cell differentiation;GO:0045639//positive regulation of myeloid cell differentiation;GO:0072070//loop of Henle development;GO:0007399//nervous system development;GO:0045747//positive regulation of Notch signaling pathway;GO:0072017//distal tubule development;GO:0030216//keratinocyte differentiation;GO:0007219//Notch signaling pathway;GO:0045445//myoblast differentiation;GO:0042491//auditory receptor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045599//negative regulation of fat cell differentiation;GO:0007220//Notch receptor processing;GO:0045665//negative regulation of neuron differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0001974//blood vessel remodeling;GO:0045446//endothelial cell differentiation;GO:0060411//cardiac septum morphogenesis,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0005509//calcium ion binding;GO:0005112//Notch binding,K06052//Notch signaling pathway
1820,0,0,0,0,0,8,0,55,16,0,16,0,ARID3A;AT rich interactive domain 3A (BRIGHT-like),GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
1821,0,0,0,0,0,32,60,2,46,182,0,0,DRP2;dystrophin related protein 2,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007417//central nervous system development,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding,K10366//Viral myocarditis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
1822,0,36,1,12,83,0,5,0,13,53,14,0,ATN1;atrophin 1,GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0005730//nucleolus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009404//toxin metabolic process;GO:0007417//central nervous system development;GO:0030011//maintenance of cell polarity;GO:0051402//neuron apoptotic process;GO:0016477//cell migration;GO:0006351//transcription, DNA-templated",GO:0019904//protein domain specific binding;GO:0003714//transcription corepressor activity;GO:0050827//toxin receptor binding;GO:0005515//protein binding,-
1823,0,0,0,0,0,19,0,0,60,0,0,0,DSC1;desmocollin 1,GO:0005921//gap junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030057//desmosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
1824,1,0,0,2,33,66,8,0,18,54,0,0,DSC2;desmocollin 2,GO:0014704//intercalated disc;GO:0030057//desmosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0005913//cell-cell adherens junction,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0009267//cellular response to starvation;GO:0007155//cell adhesion;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086042//cardiac muscle cell-cardiac muscle cell adhesion,GO:0005515//protein binding;GO:0005509//calcium ion binding,K07601//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1825,0,0,0,9,11,0,4,0,34,0,5,0,DSC3;desmocollin 3,GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0030057//desmosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0001701//in utero embryonic development;GO:0007155//cell adhesion;GO:0050821//protein stabilization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0045295//gamma-catenin binding;GO:0005509//calcium ion binding,-
1826,19,0,0,0,4,8,32,51,90,0,17,0,DSCAM;Down syndrome cell adhesion molecule,GO:0030426//growth cone;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0030424//axon;GO:0016020//membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0060060//post-embryonic retina morphogenesis in camera-type eye;GO:0007162//negative regulation of cell adhesion;GO:0048813//dendrite morphogenesis;GO:0042327//positive regulation of phosphorylation;GO:0070593//dendrite self-avoidance;GO:0007626//locomotory behavior,GO:0005515//protein binding,-
1827,0,0,0,0,1,16,16,53,0,0,0,0,RCAN1;regulator of calcineurin 1,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0033173//calcineurin-NFAT signaling cascade;GO:0006979//response to oxidative stress;GO:0007417//central nervous system development;GO:0043627//response to estrogen;GO:0002931//response to ischemia;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0009612//response to mechanical stimulus;GO:0031987//locomotion involved in locomotory behavior;GO:0007614//short-term memory;GO:0048741//skeletal muscle fiber development;GO:0006355//regulation of transcription, DNA-templated;GO:0008015//blood circulation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0007165//signal transduction",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,-
1828,0,0,0,10,17,5,19,0,19,0,0,1,DSG1;desmoglein 1,GO:0005829//cytosol;GO:0030057//desmosome;GO:0016021//integral component of membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016328//lateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005911//cell-cell junction,GO:0060135//maternal process involved in female pregnancy;GO:0006915//apoptotic process;GO:0050821//protein stabilization;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016337//single organismal cell-cell adhesion;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007043//cell-cell junction assembly;GO:0032570//response to progesterone;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding;GO:0015643//toxic substance binding;GO:0045295//gamma-catenin binding,K07596//Staphylococcus aureus infection
1829,0,0,0,0,9,13,0,1,65,0,0,0,DSG2;desmoglein 2,GO:0030057//desmosome;GO:0016324//apical plasma membrane;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0086091//regulation of heart rate by cardiac conduction;GO:0032570//response to progesterone;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0086005//ventricular cardiac muscle cell action potential;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006915//apoptotic process;GO:0060135//maternal process involved in female pregnancy;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,K07597//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
183,0,0,0,0,0,0,5,59,2,0,0,0,"AGT;angiotensinogen (serpin peptidase inhibitor, clade A, member 8)",GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007588//excretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0034374//low-density lipoprotein particle remodeling;GO:0050663//cytokine secretion;GO:0002003//angiotensin maturation;GO:0001998//angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure;GO:0010873//positive regulation of cholesterol esterification;GO:0006883//cellular sodium ion homeostasis;GO:0007267//cell-cell signaling;GO:0030198//extracellular matrix organization;GO:0008065//establishment of blood-nerve barrier;GO:0070371//ERK1 and ERK2 cascade;GO:0019229//regulation of vasoconstriction;GO:0003014//renal system process;GO:0014824//artery smooth muscle contraction;GO:0034104//negative regulation of tissue remodeling;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0014061//regulation of norepinephrine secretion;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:0009651//response to salt stress;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0035411//catenin import into nucleus;GO:0030432//peristalsis;GO:0070471//uterine smooth muscle contraction;GO:0048146//positive regulation of fibroblast proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0001558//regulation of cell growth;GO:0001568//blood vessel development;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0032270//positive regulation of cellular protein metabolic process;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0030162//regulation of proteolysis;GO:0050729//positive regulation of inflammatory response;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007263//nitric oxide mediated signal transduction;GO:0016525//negative regulation of angiogenesis;GO:0007568//aging;GO:0048143//astrocyte activation;GO:0040018//positive regulation of multicellular organism growth;GO:0002034//regulation of blood vessel size by renin-angiotensin;GO:0001819//positive regulation of cytokine production;GO:0051403//stress-activated MAPK cascade;GO:0007202//activation of phospholipase C activity;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0044255//cellular lipid metabolic process;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001974//blood vessel remodeling;GO:0044281//small molecule metabolic process;GO:0048659//smooth muscle cell proliferation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0007160//cell-matrix adhesion;GO:0071260//cellular response to mechanical stimulus;GO:0048144//fibroblast proliferation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0044267//cellular protein metabolic process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001999//renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure;GO:0010595//positive regulation of endothelial cell migration;GO:0009409//response to cold;GO:0035815//positive regulation of renal sodium excretion;GO:0032930//positive regulation of superoxide anion generation;GO:0008285//negative regulation of cell proliferation;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0046622//positive regulation of organ growth;GO:0002016//regulation of blood volume by renin-angiotensin;GO:0030308//negative regulation of cell growth;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0002019//regulation of renal output by angiotensin;GO:0010535//positive regulation of activation of JAK2 kinase activity;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001822//kidney development;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0010951//negative regulation of endopeptidase activity;GO:0042311//vasodilation;GO:0001543//ovarian follicle rupture;GO:0003051//angiotensin-mediated drinking behavior;GO:0051924//regulation of calcium ion transport;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0042127//regulation of cell proliferation;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0051145//smooth muscle cell differentiation;GO:0035813//regulation of renal sodium excretion",GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0031702//type 1 angiotensin receptor binding;GO:0005179//hormone activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0031703//type 2 angiotensin receptor binding;GO:0016176//superoxide-generating NADPH oxidase activator activity,K09821//Renin-angiotensin system
1830,0,0,0,0,0,0,31,0,36,0,0,0,DSG3;desmoglein 3,GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030057//desmosome,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006915//apoptotic process,GO:0005509//calcium ion binding,-
1831,0,153,2,121,398,0,0,9,0,0,15,0,"TSC22D3;TSC22 domain family, member 3",GO:0005634//nucleus;GO:0005829//cytosol,"GO:0006355//regulation of transcription, DNA-templated;GO:0007589//body fluid secretion;GO:0006970//response to osmotic stress;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0055085//transmembrane transport;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0034220//ion transmembrane transport",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043426//MRF binding,-
1832,3,21,0,64,311,0,4,0,89,0,8,0,DSP;desmoplakin,GO:0016323//basolateral plasma membrane;GO:0005739//mitochondrion;GO:0030057//desmosome;GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0005916//fascia adherens;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0016337//single organismal cell-cell adhesion;GO:0002934//desmosome organization;GO:0071896//protein localization to adherens junction;GO:0045109//intermediate filament organization;GO:0042060//wound healing;GO:0030216//keratinocyte differentiation;GO:0008544//epidermis development;GO:0006915//apoptotic process;GO:0003223//ventricular compact myocardium morphogenesis;GO:0086005//ventricular cardiac muscle cell action potential;GO:0034332//adherens junction organization;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0018149//peptide cross-linking,"GO:0005200//structural constituent of cytoskeleton;GO:0005198//structural molecule activity;GO:0030674//protein binding, bridging;GO:0050839//cell adhesion molecule binding;GO:0005080//protein kinase C binding;GO:0097110//scaffold protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding",K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
1833,0,0,0,0,0,0,0,0,22,0,0,0,EPYC;epiphycan,GO:0005578//proteinaceous extracellular matrix,GO:0007565//female pregnancy,GO:0005539//glycosaminoglycan binding,-
1834,0,0,0,0,0,0,22,0,10,0,9,0,DSPP;dentin sialophosphoprotein,GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0001503//ossification;GO:0030198//extracellular matrix organization;GO:0071460//cellular response to cell-matrix adhesion;GO:0001501//skeletal system development;GO:0031214//biomineral tissue development;GO:0007275//multicellular organismal development,GO:0005518//collagen binding;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding,-
1836,0,26,0,18,7,0,0,60,37,0,0,0,"SLC26A2;solute carrier family 26 (anion exchanger), member 2",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:1902358//sulfate transmembrane transport;GO:0008272//sulfate transport;GO:0006805//xenobiotic metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0001503//ossification;GO:0005975//carbohydrate metabolic process,GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity,-
1837,0,22,0,0,0,14,10,0,117,109,0,0,"DTNA;dystrobrevin, alpha",GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0030424//axon;GO:0042383//sarcolemma,GO:0007165//signal transduction;GO:0007268//synaptic transmission;GO:0007274//neuromuscular synaptic transmission;GO:0006941//striated muscle contraction,GO:0030165//PDZ domain binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K10366//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Dilated cardiomyopathy
1838,180,0,0,6,15,0,0,54,1,0,0,0,"DTNB;dystrobrevin, beta",GO:0045202//synapse;GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K10366//Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Viral myocarditis
1840,0,0,0,0,0,5,0,35,44,126,12,0,"DTX1;deltex 1, E3 ubiquitin ligase",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,"GO:0010001//glial cell differentiation;GO:0007219//Notch signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0045581//negative regulation of T cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:2001141//regulation of RNA biosynthetic process;GO:0008593//regulation of Notch signaling pathway;GO:0016567//protein ubiquitination",GO:0031625//ubiquitin protein ligase binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017124//SH3 domain binding;GO:0005112//Notch binding;GO:0003713//transcription coactivator activity,K06058//Notch signaling pathway
1841,0,0,0,0,10,0,0,0,0,0,18,0,DTYMK;deoxythymidylate kinase (thymidylate kinase),GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol,GO:0046686//response to cadmium ion;GO:0008283//cell proliferation;GO:0071363//cellular response to growth factor stimulus;GO:0043627//response to estrogen;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006235//dTTP biosynthetic process;GO:0006233//dTDP biosynthetic process;GO:0045445//myoblast differentiation;GO:0044281//small molecule metabolic process;GO:0007049//cell cycle;GO:0046940//nucleoside monophosphate phosphorylation;GO:0046939//nucleotide phosphorylation,GO:0004798//thymidylate kinase activity;GO:0005524//ATP binding;GO:0050145//nucleoside phosphate kinase activity,K00943//Metabolic pathways;One carbon pool by folate;Two-component system;Pyrimidine metabolism
1842,0,0,0,0,0,39,0,0,56,102,0,0,"ECM2;extracellular matrix protein 2, female organ and adipocyte specific",GO:0005614//interstitial matrix;GO:0005578//proteinaceous extracellular matrix,GO:0007160//cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion,GO:0005178//integrin binding;GO:0008201//heparin binding;GO:0070052//collagen V binding,-
1843,0,0,0,0,9,53,1,1,0,0,0,0,DUSP1;dual specificity phosphatase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000188//inactivation of MAPK activity;GO:0043407//negative regulation of MAP kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0051592//response to calcium ion;GO:0043065//positive regulation of apoptotic process;GO:0006979//response to oxidative stress;GO:0043409//negative regulation of MAPK cascade;GO:0032870//cellular response to hormone stimulus;GO:0042981//regulation of apoptotic process;GO:0032526//response to retinoic acid;GO:0051447//negative regulation of meiotic cell cycle;GO:0051591//response to cAMP;GO:0009416//response to light stimulus;GO:0032355//response to estradiol;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:0033574//response to testosterone;GO:0001706//endoderm formation;GO:0035556//intracellular signal transduction;GO:0042542//response to hydrogen peroxide;GO:0043066//negative regulation of apoptotic process;GO:0035970//peptidyl-threonine dephosphorylation;GO:0051384//response to glucocorticoid;GO:0071850//mitotic cell cycle arrest,GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0005515//protein binding,K04459//MAPK signaling pathway;Serotonergic synapse;Transcriptional misregulation in cancer
1845,0,2,4,42,126,11,22,0,13,34,0,0,DUSP3;dual specificity phosphatase 3,GO:0005634//nucleus;GO:0001772//immunological synapse;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0046329//negative regulation of JNK cascade;GO:0000188//inactivation of MAPK activity;GO:0050868//negative regulation of T cell activation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0043409//negative regulation of MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0045931//positive regulation of mitotic cell cycle;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0033549//MAP kinase phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K04459//Transcriptional misregulation in cancer;Serotonergic synapse;MAPK signaling pathway
1846,22,0,0,0,0,0,0,38,12,0,0,0,DUSP4;dual specificity phosphatase 4,GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0000188//inactivation of MAPK activity;GO:0006470//protein dephosphorylation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000165//MAPK cascade;GO:0001706//endoderm formation;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway,GO:0004725//protein tyrosine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330//protein tyrosine/threonine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,K04459//Transcriptional misregulation in cancer;Serotonergic synapse;MAPK signaling pathway
1847,0,0,0,0,0,1,0,0,5,0,0,0,DUSP5;dual specificity phosphatase 5,GO:0005634//nucleus,GO:0000188//inactivation of MAPK activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0001706//endoderm formation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity,K04459//MAPK signaling pathway;Transcriptional misregulation in cancer;Serotonergic synapse
1848,0,0,0,4,13,0,14,0,0,128,0,0,DUSP6;dual specificity phosphatase 6,GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0042663//regulation of endodermal cell fate specification;GO:0034138//toll-like receptor 3 signaling pathway;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0051409//response to nitrosative stress;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0009953//dorsal/ventral pattern formation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0030154//cell differentiation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0014070//response to organic cyclic compound;GO:0060420//regulation of heart growth;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0000188//inactivation of MAPK activity,GO:0004725//protein tyrosine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
1849,0,0,0,8,0,8,8,0,23,0,0,194,DUSP7;dual specificity phosphatase 7,GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0000188//inactivation of MAPK activity;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway,GO:0005515//protein binding;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K04459//Transcriptional misregulation in cancer;Serotonergic synapse;MAPK signaling pathway
185,0,0,0,0,0,0,0,0,21,19,0,0,"AGTR1;angiotensin II receptor, type 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0019722//calcium-mediated signaling;GO:0042127//regulation of cell proliferation;GO:0032430//positive regulation of phospholipase A2 activity;GO:0002034//regulation of blood vessel size by renin-angiotensin;GO:0007266//Rho protein signal transduction;GO:0035813//regulation of renal sodium excretion;GO:0050729//positive regulation of inflammatory response;GO:0086097//phospholipase C-activating angiotensin-activated signaling pathway;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0019229//regulation of vasoconstriction;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0042312//regulation of vasodilation;GO:0038166//angiotensin-activated signaling pathway;GO:0001558//regulation of cell growth;GO:0010873//positive regulation of cholesterol esterification;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0001822//kidney development;GO:0032270//positive regulation of cellular protein metabolic process;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0060326//cell chemotaxis;GO:0050727//regulation of inflammatory response;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0034374//low-density lipoprotein particle remodeling;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004945//angiotensin type II receptor activity;GO:0001596//angiotensin type I receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0031711//bradykinin receptor binding,K04166//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;Renin-angiotensin system
1850,88,0,0,0,0,0,20,0,45,0,3,0,DUSP8;dual specificity phosphatase 8,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0000188//inactivation of MAPK activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
1852,0,0,0,0,0,11,0,0,2,0,5,0,DUSP9;dual specificity phosphatase 9,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007254//JNK cascade;GO:0000188//inactivation of MAPK activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding,K04459//MAPK signaling pathway;Transcriptional misregulation in cancer;Serotonergic synapse
1854,0,1,0,0,0,0,0,0,29,0,0,0,DUT;deoxyuridine triphosphatase,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0014070//response to organic cyclic compound;GO:0043497//regulation of protein heterodimerization activity;GO:0006226//dUMP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0001889//liver development;GO:2000272//negative regulation of receptor activity;GO:0006139//nucleobase-containing compound metabolic process;GO:0070207//protein homotrimerization;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006260//DNA replication,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0032556//pyrimidine deoxyribonucleotide binding;GO:0042975//peroxisome proliferator activated receptor binding;GO:0004170//dUTP diphosphatase activity,K01520//Pyrimidine metabolism;Metabolic pathways
1855,0,0,0,1,0,0,0,18,58,0,14,0,DVL1;dishevelled segment polarity protein 1,GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0016328//lateral plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0030425//dendrite;GO:0045202//synapse;GO:0030136//clathrin-coated vesicle;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005874//microtubule;GO:0030424//axon;GO:0005829//cytosol,"GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048668//collateral sprouting;GO:0035372//protein localization to microtubule;GO:0007507//heart development;GO:0043113//receptor clustering;GO:0001505//regulation of neurotransmitter levels;GO:0032091//negative regulation of protein binding;GO:0007269//neurotransmitter secretion;GO:0035556//intracellular signal transduction;GO:0048813//dendrite morphogenesis;GO:0022007//convergent extension involved in neural plate elongation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0060134//prepulse inhibition;GO:0060026//convergent extension;GO:0090103//cochlea morphogenesis;GO:0016055//Wnt signaling pathway;GO:0035176//social behavior;GO:0007528//neuromuscular junction development;GO:0006469//negative regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0007411//axon guidance;GO:0050808//synapse organization;GO:0031122//cytoplasmic microtubule organization;GO:0060070//canonical Wnt signaling pathway;GO:0048675//axon extension;GO:0010976//positive regulation of neuron projection development;GO:0021915//neural tube development;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0030177//positive regulation of Wnt signaling pathway;GO:0034504//protein localization to nucleus;GO:0006366//transcription from RNA polymerase II promoter",GO:0019899//enzyme binding;GO:0048365//Rac GTPase binding;GO:0005109//frizzled binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K02353//Notch signaling pathway;Melanogenesis;Basal cell carcinoma;HTLV-I infection;Wnt signaling pathway;Pathways in cancer
1856,0,0,0,0,2,0,9,0,42,95,0,0,DVL2;dishevelled segment polarity protein 2,GO:0030136//clathrin-coated vesicle;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0005829//cytosol;GO:0045334//clathrin-coated endocytic vesicle;GO:0005634//nucleus,"GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0022007//convergent extension involved in neural plate elongation;GO:0060070//canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0007507//heart development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001934//positive regulation of protein phosphorylation;GO:0021535//cell migration in hindbrain;GO:0035329//hippo signaling;GO:0035567//non-canonical Wnt signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0034613//cellular protein localization;GO:0044340//canonical Wnt signaling pathway involved in regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007379//segment specification;GO:0043507//positive regulation of JUN kinase activity;GO:0016055//Wnt signaling pathway;GO:0001843//neural tube closure;GO:0060026//convergent extension;GO:0003007//heart morphogenesis;GO:0090103//cochlea morphogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0003151//outflow tract morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure",GO:0019904//protein domain specific binding;GO:0005109//frizzled binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0043621//protein self-association,K02353//Pathways in cancer;HTLV-I infection;Wnt signaling pathway;Basal cell carcinoma;Notch signaling pathway;Melanogenesis
1857,0,16,13,0,3,23,0,0,27,0,2,0,DVL3;dishevelled segment polarity protein 3,GO:0005938//cell cortex,"GO:0016055//Wnt signaling pathway;GO:0090103//cochlea morphogenesis;GO:0060026//convergent extension;GO:0042493//response to drug;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0003148//outflow tract septum morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0035567//non-canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0043507//positive regulation of JUN kinase activity",GO:0005109//frizzled binding;GO:0002020//protease binding;GO:0008013//beta-catenin binding;GO:0005102//receptor binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K02353//HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Notch signaling pathway;Melanogenesis;Basal cell carcinoma
1859,0,15,2,41,235,35,13,0,63,0,34,361,DYRK1A;dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A,GO:0016607//nuclear speck;GO:0030529//ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0018105//peptidyl-serine phosphorylation;GO:0046777//protein autophosphorylation;GO:0090312//positive regulation of protein deacetylation;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007623//circadian rhythm;GO:0007399//nervous system development;GO:0018107//peptidyl-threonine phosphorylation;GO:0000278//mitotic cell cycle",GO:0004674//protein serine/threonine kinase activity;GO:0043621//protein self-association;GO:0005515//protein binding;GO:0048156//tau protein binding;GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity,-
186,0,0,0,0,0,20,0,0,41,0,0,0,"AGTR2;angiotensin II receptor, type 2",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane,"GO:0021695//cerebellar cortex development;GO:0042990//regulation of transcription factor import into nucleus;GO:0007263//nitric oxide mediated signal transduction;GO:0002035//brain renin-angiotensin system;GO:0035640//exploration behavior;GO:0071549//cellular response to dexamethasone stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0035566//regulation of metanephros size;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0001991//regulation of systemic arterial blood pressure by circulatory renin-angiotensin;GO:0008284//positive regulation of cell proliferation;GO:1900116//extracellular negative regulation of signal transduction;GO:0002033//vasodilation by angiotensin involved in regulation of systemic arterial blood pressure;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0035556//intracellular signal transduction;GO:0007420//brain development;GO:0030308//negative regulation of cell growth;GO:0050715//positive regulation of cytokine secretion;GO:0035815//positive regulation of renal sodium excretion;GO:0032304//negative regulation of icosanoid secretion;GO:0042416//dopamine biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0045909//positive regulation of vasodilation;GO:0035932//aldosterone secretion;GO:0006954//inflammatory response;GO:0072300//positive regulation of metanephric glomerulus development;GO:0048147//negative regulation of fibroblast proliferation;GO:0010700//negative regulation of norepinephrine secretion;GO:0038166//angiotensin-activated signaling pathway;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0008217//regulation of blood pressure;GO:0001974//blood vessel remodeling;GO:0051387//negative regulation of neurotrophin TRK receptor signaling pathway;GO:0010459//negative regulation of heart rate;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006883//cellular sodium ion homeostasis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032516//positive regulation of phosphoprotein phosphatase activity",GO:0048019//receptor antagonist activity;GO:0004945//angiotensin type II receptor activity;GO:0017046//peptide hormone binding;GO:0008134//transcription factor binding;GO:0005515//protein binding,K04167//Neuroactive ligand-receptor interaction;Renin-angiotensin system
1861,0,5,0,3,9,7,0,1,15,0,0,0,"TOR1A;torsin family 1, member A (torsin A)",GO:0043231//intracellular membrane-bounded organelle;GO:0030141//secretory granule;GO:0005788//endoplasmic reticulum lumen;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0042406//extrinsic component of endoplasmic reticulum membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0008021//synaptic vesicle;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0031965//nuclear membrane;GO:0030426//growth cone;GO:0030133//transport vesicle;GO:0005856//cytoskeleton,"GO:0006998//nuclear envelope organization;GO:0000338//protein deneddylation;GO:0071712//ER-associated misfolded protein catabolic process;GO:0034504//protein localization to nucleus;GO:0072321//chaperone-mediated protein transport;GO:0007155//cell adhesion;GO:0006979//response to oxidative stress;GO:0006996//organelle organization;GO:0061077//chaperone-mediated protein folding;GO:0071763//nuclear membrane organization;GO:2000008//regulation of protein localization to cell surface;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0006200//ATP catabolic process;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0048489//synaptic vesicle transport;GO:0044319//wound healing, spreading of cells;GO:0051260//protein homooligomerization;GO:0031175//neuron projection development;GO:0045104//intermediate filament cytoskeleton organization",GO:0005524//ATP binding;GO:0008092//cytoskeletal protein binding;GO:0016887//ATPase activity;GO:0051082//unfolded protein binding;GO:0019894//kinesin binding;GO:0051787//misfolded protein binding;GO:0005515//protein binding,-
1869,0,0,0,0,0,0,0,0,28,7,1,0,E2F1;E2F transcription factor 1,GO:0035189//Rb-E2F complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0000082//G1/S transition of mitotic cell cycle;GO:0048255//mRNA stabilization;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0071398//cellular response to fatty acid;GO:1990086//lens fiber cell apoptotic process;GO:0043276//anoikis;GO:0007283//spermatogenesis;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0000077//DNA damage checkpoint;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006351//transcription, DNA-templated;GO:0048146//positive regulation of fibroblast proliferation;GO:0030900//forebrain development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:0097193//intrinsic apoptotic signaling pathway",GO:0001047//core promoter binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,K06620//Melanoma;Chronic myeloid leukemia;Non-small cell lung cancer;Cell cycle;Glioma;Bladder cancer;HTLV-I infection;Pancreatic cancer;Pathways in cancer;Small cell lung cancer;Prostate cancer
187,1,0,0,0,0,0,58,0,0,0,0,0,APLNR;apelin receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007507//heart development;GO:0050878//regulation of body fluid levels;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007369//gastrulation,GO:0004930//G-protein coupled receptor activity;GO:0004872//receptor activity,K04174//Neuroactive ligand-receptor interaction
1870,0,0,0,0,0,7,70,0,77,127,0,0,E2F2;E2F transcription factor 2,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:1990086//lens fiber cell apoptotic process;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001047//core promoter binding,K09389//Pancreatic cancer;HTLV-I infection;Pathways in cancer;Small cell lung cancer;Prostate cancer;Chronic myeloid leukemia;Melanoma;Non-small cell lung cancer;Cell cycle;Glioma;Bladder cancer
1871,4,0,0,0,11,8,25,0,37,0,12,0,E2F3;E2F transcription factor 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0007219//Notch signaling pathway;GO:0000278//mitotic cell cycle",GO:0001047//core promoter binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K06620//Prostate cancer;Small cell lung cancer;Pathways in cancer;HTLV-I infection;Pancreatic cancer;Glioma;Bladder cancer;Cell cycle;Non-small cell lung cancer;Melanoma;Chronic myeloid leukemia
1874,0,0,2,0,3,11,16,0,0,0,0,0,"E2F4;E2F transcription factor 4, p107/p130-binding",GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0002064//epithelial cell development;GO:0008361//regulation of cell size;GO:0008015//blood circulation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042384//cilium assembly;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0010467//gene expression;GO:0006884//cell volume homeostasis;GO:0009887//organ morphogenesis;GO:0000278//mitotic cell cycle",GO:0019904//protein domain specific binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding,K04682//Cell cycle;TGF-beta signaling pathway
1875,0,2,0,72,27,0,0,0,55,0,17,0,"E2F5;E2F transcription factor 5, p130-binding",GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0009887//organ morphogenesis;GO:0051726//regulation of cell cycle;GO:0000278//mitotic cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding,K04682//Cell cycle;TGF-beta signaling pathway
1876,0,0,0,15,12,36,21,0,0,0,0,0,E2F6;E2F transcription factor 6,GO:0005634//nucleus;GO:0071339//MLL1 complex;GO:0005667//transcription factor complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
1877,0,0,0,5,1,4,0,1,18,0,0,0,E4F1;E4F transcription factor 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005819//spindle,"GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0010564//regulation of cell cycle process;GO:0016032//viral process;GO:0007067//mitotic nuclear division;GO:0071850//mitotic cell cycle arrest",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0035497//cAMP response element binding;GO:0016874//ligase activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity,-
1879,62,0,0,0,0,0,26,0,9,0,0,2,EBF1;early B-cell factor 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
1889,0,0,0,8,9,22,4,0,64,0,15,0,ECE1;endothelin converting enzyme 1,GO:0033093//Weibel-Palade body;GO:0048471//perinuclear region of cytoplasm;GO:0031302//intrinsic component of endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005769//early endosome;GO:0005768//endosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0005765//lysosomal membrane,GO:0016486//peptide hormone processing;GO:0016485//protein processing;GO:0042447//hormone catabolic process;GO:0060037//pharyngeal system development;GO:0034959//endothelin maturation;GO:0007507//heart development;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0043583//ear development;GO:0010815//bradykinin catabolic process;GO:0010814//substance P catabolic process;GO:0042733//embryonic digit morphogenesis;GO:0001921//positive regulation of receptor recycling;GO:0019229//regulation of vasoconstriction;GO:0006508//proteolysis;GO:0010816//calcitonin catabolic process,GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0004222//metalloendopeptidase activity;GO:0017046//peptide hormone binding;GO:0004175//endopeptidase activity,-
189,0,0,0,0,0,15,0,15,0,143,0,0,AGXT;alanine-glyoxylate aminotransferase,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005759//mitochondrial matrix,"GO:0051591//response to cAMP;GO:0019448//L-cysteine catabolic process;GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0046724//oxalic acid secretion;GO:0042853//L-alanine catabolic process;GO:0019265//glycine biosynthetic process, by transamination of glyoxylate;GO:0009436//glyoxylate catabolic process;GO:0046487//glyoxylate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0042866//pyruvate biosynthetic process",GO:0008453//alanine-glyoxylate transaminase activity;GO:0004760//serine-pyruvate transaminase activity;GO:0008483//transaminase activity;GO:0016597//amino acid binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0030170//pyridoxal phosphate binding;GO:0005102//receptor binding,"K00830//Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Methane metabolism;Peroxisome;Glycine, serine and threonine metabolism;Glyoxylate and dicarboxylate metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
1890,0,0,0,0,0,0,0,0,30,0,0,0,TYMP;thymidine phosphorylase,GO:0005829//cytosol,GO:0006206//pyrimidine nucleobase metabolic process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0006220//pyrimidine nucleotide metabolic process;GO:0006935//chemotaxis;GO:0043097//pyrimidine nucleoside salvage;GO:0006260//DNA replication;GO:0030154//cell differentiation;GO:0044281//small molecule metabolic process;GO:0001525//angiogenesis;GO:0000002//mitochondrial genome maintenance,"GO:0016154//pyrimidine-nucleoside phosphorylase activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0016763//transferase activity, transferring pentosyl groups;GO:0009032//thymidine phosphorylase activity;GO:0004645//phosphorylase activity;GO:0008083//growth factor activity",K00758//Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism;Metabolic pathways
1891,2,1,0,1,49,0,0,0,25,0,1,89,"ECH1;enoyl CoA hydratase 1, peroxisomal",GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0006635//fatty acid beta-oxidation,GO:0005102//receptor binding;GO:0016853//isomerase activity;GO:0005515//protein binding,K12663//Peroxisome
1892,0,23,3,5,12,0,0,0,18,0,11,0,"ECHS1;enoyl CoA hydratase, short chain, 1, mitochondrial",GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0044255//cellular lipid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0044281//small molecule metabolic process,GO:0004300//enoyl-CoA hydratase activity;GO:0005515//protein binding,"K07511//Propanoate metabolism;Fatty acid elongation;Metabolic pathways;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Fatty acid metabolism;Lysine degradation;Butanoate metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites"
1893,0,0,0,0,0,0,0,0,23,0,0,0,ECM1;extracellular matrix protein 1,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0031214//biomineral tissue development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001525//angiogenesis;GO:2000404//regulation of T cell migration;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0001503//ossification;GO:0030502//negative regulation of bone mineralization;GO:0045766//positive regulation of angiogenesis;GO:0006954//inflammatory response;GO:0001938//positive regulation of endothelial cell proliferation;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0010466//negative regulation of peptidase activity;GO:0002828//regulation of type 2 immune response,GO:0043236//laminin binding;GO:0008022//protein C-terminus binding;GO:0002020//protease binding;GO:0019899//enzyme binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0005134//interleukin-2 receptor binding,-
1894,0,0,0,0,0,23,60,0,33,0,14,0,ECT2;epithelial cell transforming 2,GO:0005737//cytoplasm;GO:0097149//centralspindlin complex;GO:0005911//cell-cell junction;GO:0032154//cleavage furrow;GO:0072686//mitotic spindle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0030496//midbody;GO:0005923//tight junction,GO:0032862//activation of Rho GTPase activity;GO:0070301//cellular response to hydrogen peroxide;GO:0015031//protein transport;GO:0032147//activation of protein kinase activity;GO:0043089//positive regulation of Cdc42 GTPase activity;GO:0071479//cellular response to ionizing radiation;GO:0051260//protein homooligomerization;GO:0071277//cellular response to calcium ion;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000902//cell morphogenesis;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0042307//positive regulation of protein import into nucleus;GO:0032863//activation of Rac GTPase activity;GO:0032321//positive regulation of Rho GTPase activity;GO:0000910//cytokinesis;GO:0032467//positive regulation of cytokinesis;GO:0045666//positive regulation of neuron differentiation;GO:0045859//regulation of protein kinase activity;GO:0070830//tight junction assembly,GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity;GO:0017048//Rho GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005096//GTPase activator activity,-
1896,156,0,0,7,0,10,17,0,0,0,0,0,EDA;ectodysplasin A,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0045177//apical part of cell;GO:0005856//cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005581//collagen trimer,GO:0007165//signal transduction;GO:0043473//pigmentation;GO:0007398//ectoderm development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042475//odontogenesis of dentin-containing tooth;GO:0060789//hair follicle placode formation;GO:0030154//cell differentiation;GO:0060662//salivary gland cavitation;GO:0010467//gene expression;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0007160//cell-matrix adhesion;GO:0061153//trachea gland development;GO:0006955//immune response,GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005102//receptor binding,K05480//Cytokine-cytokine receptor interaction
19,214,0,0,0,0,1,20,18,131,94,12,1,"ABCA1;ATP-binding cassette, sub-family A (ABC1), member 1",GO:0030139//endocytic vesicle;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus,"GO:0034616//response to laminar fluid shear stress;GO:0033344//cholesterol efflux;GO:0055098//response to low-density lipoprotein particle;GO:0010887//negative regulation of cholesterol storage;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0006200//ATP catabolic process;GO:0055091//phospholipid homeostasis;GO:0071222//cellular response to lipopolysaccharide;GO:0071300//cellular response to retinoic acid;GO:0032367//intracellular cholesterol transport;GO:0042632//cholesterol homeostasis;GO:0016197//endosomal transport;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0060155//platelet dense granule organization;GO:0044255//cellular lipid metabolic process;GO:0002790//peptide secretion;GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0043691//reverse cholesterol transport;GO:0071397//cellular response to cholesterol;GO:0045332//phospholipid translocation;GO:0006911//phagocytosis, engulfment;GO:0050702//interleukin-1 beta secretion;GO:0007040//lysosome organization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008203//cholesterol metabolic process;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0042157//lipoprotein metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0034380//high-density lipoprotein particle assembly;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0007584//response to nutrient;GO:0006497//protein lipidation;GO:0033700//phospholipid efflux",GO:0005524//ATP binding;GO:0034188//apolipoprotein A-I receptor activity;GO:0017127//cholesterol transporter activity;GO:0005548//phospholipid transporter activity;GO:0016887//ATPase activity;GO:0019905//syntaxin binding;GO:0051117//ATPase binding;GO:0015485//cholesterol binding;GO:0034186//apolipoprotein A-I binding;GO:0008509//anion transmembrane transporter activity;GO:0005102//receptor binding;GO:0034185//apolipoprotein binding;GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0031267//small GTPase binding,K05641//Fat digestion and absorption;ABC transporters
190,0,0,0,0,0,0,0,0,13,0,0,0,"NR0B1;nuclear receptor subfamily 0, group B, member 1",GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0042788//polysomal ribosome;GO:0005654//nucleoplasm,"GO:0030522//intracellular receptor signaling pathway;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0060008//Sertoli cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0043401//steroid hormone mediated signaling pathway;GO:0008406//gonad development;GO:0021983//pituitary gland development;GO:0006694//steroid biosynthetic process;GO:0033327//Leydig cell differentiation;GO:0030238//male sex determination;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0035902//response to immobilization stress;GO:0010467//gene expression;GO:0030325//adrenal gland development;GO:0008104//protein localization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0021854//hypothalamus development",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0050682//AF-2 domain binding;GO:0003723//RNA binding;GO:0003714//transcription corepressor activity;GO:0019904//protein domain specific binding;GO:0035258//steroid hormone receptor binding;GO:0003707//steroid hormone receptor activity;GO:0032448//DNA hairpin binding;GO:0008134//transcription factor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
1901,0,0,0,0,0,8,0,0,4,0,10,0,S1PR1;sphingosine-1-phosphate receptor 1,GO:0005768//endosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane,GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016477//cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051497//negative regulation of stress fiber assembly;GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0045124//regulation of bone resorption;GO:0006935//chemotaxis;GO:0030182//neuron differentiation;GO:0030155//regulation of cell adhesion;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0072678//T cell migration;GO:0032320//positive regulation of Ras GTPase activity;GO:0007155//cell adhesion;GO:0030032//lamellipodium assembly;GO:0001955//blood vessel maturation;GO:0050927//positive regulation of positive chemotaxis;GO:0003245//cardiac muscle tissue growth involved in heart morphogenesis;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0001525//angiogenesis;GO:0030500//regulation of bone mineralization;GO:0045446//endothelial cell differentiation;GO:0061384//heart trabecula morphogenesis;GO:0019226//transmission of nerve impulse;GO:0007420//brain development;GO:0031532//actin cytoskeleton reorganization;GO:0030335//positive regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway,GO:0038036//sphingosine-1-phosphate receptor activity;GO:0046625//sphingolipid binding;GO:0001664//G-protein coupled receptor binding;GO:0004930//G-protein coupled receptor activity,K04288//Neuroactive ligand-receptor interaction
1902,0,0,0,0,0,0,35,0,14,0,0,0,LPAR1;lysophosphatidic acid receptor 1,GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0030139//endocytic vesicle;GO:0009986//cell surface;GO:0043197//dendritic spine;GO:0005887//integral component of plasma membrane,GO:0071673//positive regulation of smooth muscle cell chemotaxis;GO:0010977//negative regulation of neuron projection development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060999//positive regulation of dendritic spine development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032060//bleb assembly;GO:0007202//activation of phospholipase C activity;GO:0043065//positive regulation of apoptotic process;GO:0000187//activation of MAPK activity;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0071453//cellular response to oxygen levels;GO:0042552//myelination,GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0070915//lysophosphatidic acid receptor activity;GO:0030165//PDZ domain binding;GO:0001965//G-protein alpha-subunit binding;GO:0004930//G-protein coupled receptor activity,K04289//Gap junction;Neuroactive ligand-receptor interaction
1903,0,0,0,0,0,0,0,0,33,0,0,0,S1PR3;sphingosine-1-phosphate receptor 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0001816//cytokine production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0032651//regulation of interleukin-1 beta production;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006954//inflammatory response;GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation,GO:0004930//G-protein coupled receptor activity;GO:0008289//lipid binding;GO:0005178//integrin binding;GO:0038036//sphingosine-1-phosphate receptor activity,K04290//Neuroactive ligand-receptor interaction
1906,0,0,0,0,0,0,41,0,0,0,0,0,EDN1;endothelin 1,GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0014824//artery smooth muscle contraction;GO:0019722//calcium-mediated signaling;GO:0007589//body fluid secretion;GO:0019229//regulation of vasoconstriction;GO:0001666//response to hypoxia;GO:0014032//neural crest cell development;GO:0031583//phospholipase D-activating G-protein coupled receptor signaling pathway;GO:0043200//response to amino acid;GO:0042554//superoxide anion generation;GO:0035810//positive regulation of urine volume;GO:0045793//positive regulation of cell size;GO:0045987//positive regulation of smooth muscle contraction;GO:0007267//cell-cell signaling;GO:0042493//response to drug;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0030335//positive regulation of cell migration;GO:0045321//leukocyte activation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033574//response to testosterone;GO:0030593//neutrophil chemotaxis;GO:0032269//negative regulation of cellular protein metabolic process;GO:0042045//epithelial fluid transport;GO:0010259//multicellular organismal aging;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0042474//middle ear morphogenesis;GO:0014826//vein smooth muscle contraction;GO:0030195//negative regulation of blood coagulation;GO:0051216//cartilage development;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007507//heart development;GO:0016049//cell growth;GO:0010460//positive regulation of heart rate;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030185//nitric oxide transport;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0010870//positive regulation of receptor biosynthetic process;GO:0043507//positive regulation of JUN kinase activity;GO:0046888//negative regulation of hormone secretion;GO:0051930//regulation of sensory perception of pain;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0001516//prostaglandin biosynthetic process;GO:0042482//positive regulation of odontogenesis;GO:0060137//maternal process involved in parturition;GO:0043406//positive regulation of MAP kinase activity;GO:0006885//regulation of pH;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0007585//respiratory gaseous exchange;GO:0070101//positive regulation of chemokine-mediated signaling pathway;GO:0046887//positive regulation of hormone secretion;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0009953//dorsal/ventral pattern formation;GO:0015758//glucose transport;GO:0030072//peptide hormone secretion;GO:0032496//response to lipopolysaccharide;GO:0042313//protein kinase C deactivation;GO:0071356//cellular response to tumor necrosis factor;GO:0048016//inositol phosphate-mediated signaling;GO:0060298//positive regulation of sarcomere organization;GO:0001569//patterning of blood vessels;GO:0035094//response to nicotine;GO:0001821//histamine secretion;GO:0019233//sensory perception of pain;GO:0051899//membrane depolarization;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0071347//cellular response to interleukin-1;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0045840//positive regulation of mitosis;GO:0008284//positive regulation of cell proliferation;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0010595//positive regulation of endothelial cell migration;GO:0043179//rhythmic excitation;GO:0035815//positive regulation of renal sodium excretion,GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0031708//endothelin B receptor binding;GO:0005179//hormone activity;GO:0031707//endothelin A receptor binding,K05227//Melanogenesis
1909,42,0,37,0,0,58,0,0,22,0,0,0,EDNRA;endothelin receptor type A,GO:0031965//nuclear membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030315//T-tubule,GO:0048144//fibroblast proliferation;GO:0071260//cellular response to mechanical stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050678//regulation of epithelial cell proliferation;GO:0001666//response to hypoxia;GO:0014032//neural crest cell development;GO:0008217//regulation of blood pressure;GO:0042482//positive regulation of odontogenesis;GO:0007165//signal transduction;GO:0043084//penile erection;GO:0007266//Rho protein signal transduction;GO:0043278//response to morphine;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0014824//artery smooth muscle contraction;GO:0003094//glomerular filtration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0008152//metabolic process;GO:0007202//activation of phospholipase C activity;GO:0090184//positive regulation of kidney development;GO:0060322//head development;GO:0048484//enteric nervous system development;GO:0007190//activation of adenylate cyclase activity;GO:0015758//glucose transport;GO:0032496//response to lipopolysaccharide;GO:0060137//maternal process involved in parturition;GO:0048659//smooth muscle cell proliferation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0007585//respiratory gaseous exchange;GO:0001934//positive regulation of protein phosphorylation;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0050729//positive regulation of inflammatory response;GO:0001569//patterning of blood vessels;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0001821//histamine secretion;GO:0019233//sensory perception of pain;GO:0006939//smooth muscle contraction;GO:0007568//aging;GO:0043066//negative regulation of apoptotic process;GO:0008283//cell proliferation;GO:0086100//endothelin receptor signaling pathway;GO:0007507//heart development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0004962//endothelin receptor activity,K04197//Vascular smooth muscle contraction;Neuroactive ligand-receptor interaction;Calcium signaling pathway
191,184,83,1,42,79,27,15,0,20,0,11,85,AHCY;adenosylhomocysteinase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043005//neuron projection;GO:0042470//melanosome;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0002439//chronic inflammatory response to antigenic stimulus;GO:0001666//response to hypoxia;GO:0007584//response to nutrient;GO:0000096//sulfur amino acid metabolic process;GO:0042745//circadian sleep/wake cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0006730//one-carbon metabolic process;GO:0032259//methylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0004013//adenosylhomocysteinase activity;GO:0030554//adenyl nucleotide binding;GO:0051287//NAD binding;GO:0042802//identical protein binding,K01251//Cysteine and methionine metabolism;Metabolic pathways
1910,0,0,0,6,31,17,15,0,24,56,0,0,EDNRB;endothelin receptor type B,GO:0031965//nuclear membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0045121//membrane raft,GO:0042310//vasoconstriction;GO:0007497//posterior midgut development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031620//regulation of fever generation;GO:0007194//negative regulation of adenylate cyclase activity;GO:0048484//enteric nervous system development;GO:0007422//peripheral nervous system development;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0032269//negative regulation of cellular protein metabolic process;GO:0042045//epithelial fluid transport;GO:0035810//positive regulation of urine volume;GO:0006885//regulation of pH;GO:0007399//nervous system development;GO:0048265//response to pain;GO:0048246//macrophage chemotaxis;GO:0014043//negative regulation of neuron maturation;GO:0051930//regulation of sensory perception of pain;GO:0008217//regulation of blood pressure;GO:0050678//regulation of epithelial cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0035815//positive regulation of renal sodium excretion;GO:0086100//endothelin receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060406//positive regulation of penile erection;GO:0008284//positive regulation of cell proliferation;GO:0001755//neural crest cell migration;GO:0035645//enteric smooth muscle cell differentiation;GO:0014826//vein smooth muscle contraction;GO:0001934//positive regulation of protein phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0042311//vasodilation;GO:0030318//melanocyte differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0019233//sensory perception of pain;GO:0019934//cGMP-mediated signaling;GO:0007568//aging;GO:0014070//response to organic cyclic compound,GO:0017046//peptide hormone binding;GO:0005515//protein binding;GO:0031702//type 1 angiotensin receptor binding;GO:0004962//endothelin receptor activity,K04198//Neuroactive ligand-receptor interaction;Melanogenesis;Calcium signaling pathway
1911,0,55,129,110,42,82,20,41,37,0,89,0,PHC1;polyhomeotic homolog 1 (Drosophila),GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005634//nucleus;GO:0001739//sex chromatin;GO:0005730//nucleolus;GO:0035102//PRC1 complex;GO:0031519//PcG protein complex,GO:0016574//histone ubiquitination;GO:0071300//cellular response to retinoic acid;GO:0007275//multicellular organismal development,GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
1912,70,0,0,9,21,0,20,65,30,0,0,5,PHC2;polyhomeotic homolog 2 (Drosophila),GO:0005634//nucleus;GO:0000792//heterochromatin;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0005730//nucleolus;GO:0035102//PRC1 complex,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
1915,43,1892,93,2173,9355,2,3,97,23,1,34,0,EEF1A1;eukaryotic translation elongation factor 1 alpha 1,GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0006351//transcription, DNA-templated;GO:0006184//GTP catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006414//translational elongation",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003746//translation elongation factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019901//protein kinase binding,K03231//Leishmaniasis;Legionellosis;RNA transport
191585,6,0,0,0,0,10,44,0,62,0,4,310,PLAC4;placenta-specific 4,-,-,-,-
1917,0,0,0,0,1,0,0,41,13,0,0,0,EEF1A2;eukaryotic translation elongation factor 1 alpha 2,GO:0005853//eukaryotic translation elongation factor 1 complex;GO:0043025//neuronal cell body;GO:0005634//nucleus,GO:0006414//translational elongation;GO:0043065//positive regulation of apoptotic process;GO:0006184//GTP catabolic process;GO:0010035//response to inorganic substance,"GO:0008135//translation factor activity, nucleic acid binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0003746//translation elongation factor activity",K03231//RNA transport;Legionellosis;Leishmaniasis
192111,0,0,0,9,6,0,0,0,13,0,0,0,PGAM5;phosphoglycerate mutase family member 5,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0043547//positive regulation of GTPase activity;GO:0070266//necroptotic process;GO:0016311//dephosphorylation,GO:0004721//phosphoprotein phosphatase activity;GO:0016791//phosphatase activity;GO:0005096//GTPase activator activity;GO:0032403//protein complex binding,-
192286,135,2,0,5,33,0,17,5,8,0,0,0,"HIGD2A;HIG1 hypoxia inducible domain family, member 2A",GO:0005743//mitochondrial inner membrane;GO:0070469//respiratory chain;GO:0016021//integral component of membrane,GO:0043066//negative regulation of apoptotic process;GO:0055114//oxidation-reduction process,-,-
192666,0,0,0,0,0,21,0,0,2,0,0,0,KRT24;keratin 24,GO:0005737//cytoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
192668,0,0,0,0,0,7,24,0,23,3,1,0,CYS1;cystin 1,GO:0060170//ciliary membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,GO:0005515//protein binding,-
192669,36,0,0,9,25,28,0,0,19,0,0,0,AGO3;argonaute RISC catalytic component 3,GO:0016442//RISC complex;GO:0000932//cytoplasmic mRNA processing body;GO:0016020//membrane;GO:0005829//cytosol;GO:0035068//micro-ribonucleoprotein complex,GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006402//mRNA catabolic process;GO:0010467//gene expression;GO:0045087//innate immune response;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0072091//regulation of stem cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0035198//miRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
192670,0,2,29,26,41,0,0,0,12,0,17,0,AGO4;argonaute RISC catalytic component 4,GO:0000932//cytoplasmic mRNA processing body;GO:0016442//RISC complex;GO:0035068//micro-ribonucleoprotein complex;GO:0005829//cytosol;GO:0016020//membrane,GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006402//mRNA catabolic process;GO:0010467//gene expression;GO:0007219//Notch signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0035198//miRNA binding;GO:0005515//protein binding,-
192683,59,0,0,0,1,17,14,0,0,0,0,0,SCAMP5;secretory carrier membrane protein 5,GO:0031201//SNARE complex;GO:0030672//synaptic vesicle membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0055038//recycling endosome membrane;GO:0032588//trans-Golgi network membrane,GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0006887//exocytosis;GO:0050715//positive regulation of cytokine secretion;GO:0034976//response to endoplasmic reticulum stress;GO:0045806//negative regulation of endocytosis;GO:0015031//protein transport,GO:0005515//protein binding,K08823//Legionellosis
1933,0,1,0,40,111,0,2,0,32,0,15,0,EEF1B2;eukaryotic translation elongation factor 1 beta 2,GO:0005829//cytosol;GO:0005853//eukaryotic translation elongation factor 1 complex,GO:0006412//translation;GO:0044267//cellular protein metabolic process;GO:0006414//translational elongation;GO:0010467//gene expression,GO:0005515//protein binding;GO:0003746//translation elongation factor activity,-
1936,0,86,9,25,64,11,31,101,15,0,19,0,EEF1D;eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005853//eukaryotic translation elongation factor 1 complex,"GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006414//translational elongation;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling","GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity;GO:0003746//translation elongation factor activity",K15410//Herpes simplex infection
1937,121,272,9,230,612,0,0,1,39,0,1,0,EEF1G;eukaryotic translation elongation factor 1 gamma,GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0010467//gene expression;GO:0006414//translational elongation;GO:0009615//response to virus;GO:0044267//cellular protein metabolic process;GO:0006412//translation,GO:0005515//protein binding;GO:0003746//translation elongation factor activity,K03233//Legionellosis
1938,61,317,20,134,752,11,95,6,23,0,34,2,EEF2;eukaryotic translation elongation factor 2,GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0005844//polysome,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0006412//translation;GO:0006184//GTP catabolic process;GO:0006414//translational elongation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0008219//cell death;GO:0045727//positive regulation of translation,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003746//translation elongation factor activity;GO:0044822//poly(A) RNA binding;GO:0019901//protein kinase binding;GO:0008494//translation activator activity,-
1939,93,1,2,13,42,4,47,0,0,144,0,0,EIF2D;eukaryotic translation initiation factor 2D,GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0001731//formation of translation preinitiation complex;GO:0006886//intracellular protein transport;GO:0032790//ribosome disassembly;GO:0002192//IRES-dependent translational initiation,GO:0004872//receptor activity;GO:0003743//translation initiation factor activity,-
1942,74,0,0,0,15,13,11,2,8,0,0,0,EFNA1;ephrin-A1,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0046658//anchored component of plasma membrane,GO:0007267//cell-cell signaling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001525//angiogenesis;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0000187//activation of MAPK activity;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0007411//axon guidance;GO:0050770//regulation of axonogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0003180//aortic valve morphogenesis;GO:0045765//regulation of angiogenesis;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0016477//cell migration;GO:0014028//notochord formation;GO:0003183//mitral valve morphogenesis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0010719//negative regulation of epithelial to mesenchymal transition,GO:0005102//receptor binding;GO:0046875//ephrin receptor binding;GO:0005515//protein binding,K05462//Axon guidance
1943,127,0,0,0,0,0,0,0,0,5,0,0,EFNA2;ephrin-A2,GO:0031225//anchored component of membrane;GO:0031594//neuromuscular junction;GO:0043204//perikaryon;GO:0005886//plasma membrane,GO:0021772//olfactory bulb development;GO:0007267//cell-cell signaling;GO:0030316//osteoclast differentiation;GO:0007411//axon guidance;GO:0046849//bone remodeling;GO:0048013//ephrin receptor signaling pathway,GO:0046875//ephrin receptor binding,K05462//Axon guidance
1944,22,33,0,0,0,0,0,0,25,7,0,0,EFNA3;ephrin-A3,GO:0031225//anchored component of membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0007411//axon guidance,GO:0005005//transmembrane-ephrin receptor activity;GO:0046875//ephrin receptor binding,K05462//Axon guidance
1945,0,29,0,0,8,0,0,0,2,0,0,0,EFNA4;ephrin-A4,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0031225//anchored component of membrane;GO:0005887//integral component of plasma membrane,GO:0030316//osteoclast differentiation;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:0007411//axon guidance;GO:0046849//bone remodeling,GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0046875//ephrin receptor binding,K05462//Axon guidance
1946,0,3,0,0,0,34,0,26,37,0,0,0,EFNA5;ephrin-A5,GO:0005886//plasma membrane;GO:0005901//caveola;GO:0031362//anchored component of external side of plasma membrane,GO:0032314//regulation of Rac GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0022407//regulation of cell-cell adhesion;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0031290//retinal ganglion cell axon guidance;GO:0050919//negative chemotaxis;GO:0032319//regulation of Rho GTPase activity;GO:0051893//regulation of focal adhesion assembly;GO:0006915//apoptotic process;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0032956//regulation of actin cytoskeleton organization;GO:0007411//axon guidance;GO:0007399//nervous system development,GO:0046875//ephrin receptor binding;GO:0045499//chemorepellent activity,K05462//Axon guidance
1947,1,0,0,0,4,38,0,0,6,0,14,348,EFNB1;ephrin-B1,GO:0045121//membrane raft;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007267//cell-cell signaling;GO:0042102//positive regulation of T cell proliferation;GO:0007155//cell adhesion;GO:0048013//ephrin receptor signaling pathway;GO:0009880//embryonic pattern specification;GO:0007411//axon guidance;GO:0001755//neural crest cell migration,GO:0005515//protein binding;GO:0046875//ephrin receptor binding,K05463//Axon guidance
1948,0,0,0,5,1,0,44,68,22,0,1,0,EFNB2;ephrin-B2,GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0050920//regulation of chemotaxis;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0001945//lymph vessel development;GO:0009653//anatomical structure morphogenesis;GO:0010839//negative regulation of keratinocyte proliferation;GO:0007155//cell adhesion;GO:0009887//organ morphogenesis;GO:0007411//axon guidance;GO:0016032//viral process;GO:0007267//cell-cell signaling;GO:0048013//ephrin receptor signaling pathway;GO:2000727//positive regulation of cardiac muscle cell differentiation,GO:0046875//ephrin receptor binding;GO:0005515//protein binding,K05463//Axon guidance
1949,115,0,0,0,0,0,9,0,0,0,0,0,EFNB3;ephrin-B3,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0048013//ephrin receptor signaling pathway;GO:0007628//adult walking behavior;GO:0007267//cell-cell signaling;GO:0016032//viral process,GO:0046875//ephrin receptor binding;GO:0005005//transmembrane-ephrin receptor activity,K05463//Axon guidance
1950,0,0,0,0,0,18,0,0,9,0,0,0,EGF;epidermal growth factor,GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region,"GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0045840//positive regulation of mitosis;GO:0002576//platelet degranulation;GO:0090279//regulation of calcium ion import;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0001525//angiogenesis;GO:0000186//activation of MAPKK activity;GO:0035413//positive regulation of catenin import into nucleus;GO:0090370//negative regulation of cholesterol efflux;GO:0043388//positive regulation of DNA binding;GO:0060749//mammary gland alveolus development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0048015//phosphatidylinositol-mediated signaling;GO:2000008//regulation of protein localization to cell surface;GO:0007262//STAT protein import into nucleus;GO:0007165//signal transduction;GO:0051048//negative regulation of secretion;GO:0070371//ERK1 and ERK2 cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006260//DNA replication;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0042327//positive regulation of phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0018108//peptidyl-tyrosine phosphorylation",GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0008083//growth factor activity;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0005154//epidermal growth factor receptor binding,K04357//Prostate cancer;Pancreatic cancer;Endocytosis;Pathways in cancer;Gap junction;Bladder cancer;ErbB signaling pathway;Cytokine-cytokine receptor interaction;MAPK signaling pathway;Focal adhesion;Glioma;Melanoma;Regulation of actin cytoskeleton;Hepatitis C;Endometrial cancer;Non-small cell lung cancer
1951,4,0,0,0,0,36,12,118,84,0,22,0,"CELSR3;cadherin, EGF LAG seven-pass G-type receptor 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0032880//regulation of protein localization;GO:0001764//neuron migration;GO:0007413//axonal fasciculation;GO:0007218//neuropeptide signaling pathway;GO:0042384//cilium assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding,-
1952,296,0,11,0,1,29,41,0,87,0,0,0,"CELSR2;cadherin, EGF LAG seven-pass G-type receptor 2",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,"GO:0001764//neuron migration;GO:0021999//neural plate anterior/posterior regionalization;GO:0048813//dendrite morphogenesis;GO:0007218//neuropeptide signaling pathway;GO:0042384//cilium assembly;GO:0003341//cilium movement;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032880//regulation of protein localization;GO:0033326//cerebrospinal fluid secretion;GO:0022407//regulation of cell-cell adhesion;GO:0016055//Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0021591//ventricular system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules",GO:0004930//G-protein coupled receptor activity;GO:0005509//calcium ion binding,-
1953,0,0,0,0,0,11,0,68,82,48,0,0,MEGF6;multiple EGF-like-domains 6,GO:0005576//extracellular region,-,GO:0005509//calcium ion binding;GO:0005515//protein binding,K02599//Dorso-ventral axis formation;Notch signaling pathway;Prion diseases
1954,131,0,0,0,0,1,58,9,90,0,29,0,MEGF8;multiple EGF-like-domains 8,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0071907//determination of digestive tract left/right asymmetry;GO:0035108//limb morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0030509//BMP signaling pathway;GO:0097155//fasciculation of sensory neuron axon;GO:0010468//regulation of gene expression;GO:0060972//left/right pattern formation;GO:0003143//embryonic heart tube morphogenesis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0061371//determination of heart left/right asymmetry;GO:0042074//cell migration involved in gastrulation;GO:0055113//epiboly involved in gastrulation with mouth forming second;GO:0030326//embryonic limb morphogenesis;GO:0097094//craniofacial suture morphogenesis;GO:0060971//embryonic heart tube left/right pattern formation,GO:0004872//receptor activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
1955,65,0,0,0,27,18,26,0,31,0,13,0,MEGF9;multiple EGF-like-domains 9,GO:0016021//integral component of membrane,-,-,K06243//Amoebiasis;Small cell lung cancer;Focal adhesion;ECM-receptor interaction;Toxoplasmosis;Pathways in cancer
1956,0,50,0,0,0,55,60,105,44,0,18,0,EGFR;epidermal growth factor receptor,GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005768//endosome;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0070435//Shc-EGFR complex;GO:0016324//apical plasma membrane;GO:0030122//AP-2 adaptor complex;GO:0043235//receptor complex;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm,"GO:0043406//positive regulation of MAP kinase activity;GO:0007611//learning or memory;GO:0043586//tongue development;GO:0042327//positive regulation of phosphorylation;GO:0071230//cellular response to amino acid stimulus;GO:0001503//ossification;GO:0051205//protein insertion into membrane;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0007411//axon guidance;GO:0007202//activation of phospholipase C activity;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0070141//response to UV-A;GO:0060571//morphogenesis of an epithelial fold;GO:0016101//diterpenoid metabolic process;GO:0071260//cellular response to mechanical stimulus;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0021795//cerebral cortex cell migration;GO:0001889//liver development;GO:0045930//negative regulation of mitotic cell cycle;GO:0051897//positive regulation of protein kinase B signaling;GO:0001942//hair follicle development;GO:0033594//response to hydroxyisoflavone;GO:0008284//positive regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0005976//polysaccharide metabolic process;GO:0032930//positive regulation of superoxide anion generation;GO:0035413//positive regulation of catenin import into nucleus;GO:0042698//ovulation cycle;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0006979//response to oxidative stress;GO:0045907//positive regulation of vasoconstriction;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0071549//cellular response to dexamethasone stimulus;GO:0007435//salivary gland morphogenesis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043006//activation of phospholipase A2 activity by calcium-mediated signaling;GO:0030335//positive regulation of cell migration;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0000165//MAPK cascade;GO:0071392//cellular response to estradiol stimulus;GO:0006412//translation;GO:0035690//cellular response to drug;GO:0045739//positive regulation of DNA repair;GO:0010960//magnesium ion homeostasis;GO:0045909//positive regulation of vasodilation;GO:0007165//signal transduction;GO:0019694//alkanesulfonate metabolic process;GO:0046777//protein autophosphorylation;GO:0006970//response to osmotic stress;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048546//digestive tract morphogenesis;GO:0042177//negative regulation of protein catabolic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045740//positive regulation of DNA replication;GO:0030324//lung development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0042743//hydrogen peroxide metabolic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0033590//response to cobalamin;GO:0045087//innate immune response;GO:0016337//single organismal cell-cell adhesion;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0001892//embryonic placenta development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048143//astrocyte activation;GO:0007623//circadian rhythm;GO:0051592//response to calcium ion;GO:0001934//positive regulation of protein phosphorylation;GO:0050729//positive regulation of inflammatory response;GO:0050999//regulation of nitric-oxide synthase activity",GO:0001948//glycoprotein binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0005006//epidermal growth factor-activated receptor activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0019903//protein phosphatase binding;GO:0031625//ubiquitin protein ligase binding;GO:0004888//transmembrane signaling receptor activity;GO:0051015//actin filament binding;GO:0003690//double-stranded DNA binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0046982//protein heterodimerization activity;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0048408//epidermal growth factor binding,K04361//Prostate cancer;Pathways in cancer;GnRH signaling pathway;Gap junction;Pancreatic cancer;Endocytosis;Bladder cancer;Adherens junction;ErbB signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Calcium signaling pathway;Glioma;Dorso-ventral axis formation;Focal adhesion;MAPK signaling pathway - fly;Non-small cell lung cancer;Endometrial cancer;Regulation of actin cytoskeleton;Melanoma;Hepatitis C
195814,0,0,0,0,0,52,52,0,29,1,0,238,"SDR16C5;short chain dehydrogenase/reductase family 16C, member 5",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0042574//retinal metabolic process;GO:0042572//retinol metabolic process;GO:0043616//keratinocyte proliferation;GO:0050908//detection of light stimulus involved in visual perception;GO:0055114//oxidation-reduction process,GO:0004745//retinol dehydrogenase activity,K15734//Retinol metabolism
195827,0,0,0,0,13,26,0,0,3,0,0,0,AAED1;AhpC/TSA antioxidant enzyme domain containing 1,-,-,-,K15717//Arachidonic acid metabolism;Metabolic pathways
195828,0,0,0,0,0,22,0,0,26,0,0,0,ZNF367;zinc finger protein 367,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K10207//Steroid hormone biosynthesis;Metabolic pathways
1959,27,0,0,0,0,0,0,0,14,0,0,0,EGR2;early growth response 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0042552//myelination;GO:0071320//cellular response to cAMP;GO:0071371//cellular response to gonadotropin stimulus;GO:0030278//regulation of ossification;GO:0006611//protein export from nucleus;GO:0016925//protein sumoylation;GO:0007622//rhythmic behavior;GO:0021612//facial nerve structural organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0014037//Schwann cell differentiation;GO:0035284//brain segmentation;GO:0007422//peripheral nervous system development;GO:0008045//motor neuron axon guidance;GO:0007420//brain development;GO:0043066//negative regulation of apoptotic process;GO:0048168//regulation of neuronal synaptic plasticity;GO:0008219//cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035914//skeletal muscle cell differentiation;GO:0007611//learning or memory;GO:0032868//response to insulin",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0016874//ligase activity;GO:0071837//HMG box domain binding;GO:0003682//chromatin binding,K12496//HTLV-I infection
195977,0,0,0,0,0,0,0,64,0,0,0,0,ANTXRL;anthrax toxin receptor-like,GO:0016021//integral component of membrane,-,GO:0004872//receptor activity;GO:0046872//metal ion binding,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
196,0,1,0,0,11,10,0,0,50,0,0,0,AHR;aryl hydrocarbon receptor,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0034752//cytosolic aryl hydrocarbon receptor complex,"GO:0030888//regulation of B cell proliferation;GO:0032922//circadian regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030850//prostate gland development;GO:0045899//positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0009410//response to xenobiotic stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0001568//blood vessel development;GO:0007049//cell cycle;GO:0009636//response to toxic substance;GO:0006805//xenobiotic metabolic process;GO:0010468//regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030522//intracellular receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0035326//enhancer binding;GO:0046983//protein dimerization activity;GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0051879//Hsp90 protein binding;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0070888//E-box binding;GO:0008134//transcription factor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,-
1960,4,59,57,27,65,0,0,424,25,0,257,0,EGR3;early growth response 3,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0033089//positive regulation of T cell differentiation in thymus;GO:0007274//neuromuscular synaptic transmission;GO:0035767//endothelial cell chemotaxis;GO:0007623//circadian rhythm;GO:0007517//muscle organ development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0071371//cellular response to gonadotropin stimulus;GO:0071320//cellular response to cAMP;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0007422//peripheral nervous system development;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0002042//cell migration involved in sprouting angiogenesis",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
196051,0,0,0,0,0,0,50,0,25,0,0,0,PPAPDC1A;phosphatidic acid phosphatase type 2 domain containing 1A,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0045087//innate immune response;GO:0046839//phospholipid dephosphorylation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0008195//phosphatidate phosphatase activity,K01080//Sphingolipid metabolism;Ether lipid metabolism;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism
1961,0,0,0,0,0,0,0,0,40,0,0,0,EGR4;early growth response 4,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008284//positive regulation of cell proliferation;GO:0071371//cellular response to gonadotropin stimulus;GO:0071320//cellular response to cAMP;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
1962,0,30,0,93,184,0,0,0,27,0,3,1,"EHHADH;enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005777//peroxisome,GO:0006475//internal protein amino acid acetylation;GO:0006635//fatty acid beta-oxidation,GO:0050662//coenzyme binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0005102//receptor binding;GO:0019899//enzyme binding;GO:0004165//dodecenoyl-CoA delta-isomerase activity;GO:0004300//enoyl-CoA hydratase activity,"K07514//Butanoate metabolism;PPAR signaling pathway;Tryptophan metabolism;Peroxisome;Propanoate metabolism;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Metabolic pathways;Fatty acid metabolism;Lysine degradation"
196264,0,0,0,0,0,21,0,0,14,0,4,0,MPZL3;myelin protein zero-like 3,GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0042633//hair cycle;GO:0030198//extracellular matrix organization,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K06770//Cell adhesion molecules (CAMs);K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
196294,0,22,0,13,13,0,0,0,0,0,0,0,IMMP1L;IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae),GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity,K09647//Protein export
196335,0,0,0,2,0,0,0,0,10,0,0,0,"OR56B4;olfactory receptor, family 56, subfamily B, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
196374,0,0,0,0,0,0,0,0,11,0,0,0,KRT78;keratin 78,GO:0045095//keratin filament;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,-,GO:0005198//structural molecule activity,-
196383,0,0,0,5,13,0,0,63,1,0,14,0,RILPL2;Rab interacting lysosomal protein-like 2,GO:0005829//cytosol;GO:0072372//primary cilium;GO:0070062//extracellular vesicular exosome;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0003382//epithelial cell morphogenesis;GO:0006886//intracellular protein transport,GO:0042802//identical protein binding,K13883//Phagosome;Salmonella infection
196385,0,106,46,143,116,107,11,171,123,1,135,0,"DNAH10;dynein, axonemal, heavy chain 10",GO:0005929//cilium;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm,GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,K10408//Huntington's disease;K01509//Purine metabolism
196394,0,0,0,27,88,9,17,0,0,0,18,0,AMN1;antagonist of mitotic exit network 1 homolog (S. cerevisiae),-,-,-,-
1964,0,25,1,120,146,0,0,0,18,0,0,0,"EIF1AX;eukaryotic translation initiation factor 1A, X-linked",GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006413//translational initiation,"GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding",K03236//RNA transport
196403,0,1,0,0,0,3,0,0,0,0,2,0,"DTX3;deltex 3, E3 ubiquitin ligase",GO:0005737//cytoplasm,GO:0007219//Notch signaling pathway;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0008270//zinc ion binding,K06058//Notch signaling pathway
196410,0,0,0,0,0,0,0,0,12,0,0,0,METTL7B;methyltransferase like 7B,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
196441,0,73,1,8,32,21,59,11,55,2,31,0,"ZFC3H1;zinc finger, C3H1-type containing",GO:0005622//intracellular;GO:0005615//extracellular space,GO:0006396//RNA processing,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
196463,64,0,0,0,0,15,12,0,18,0,0,0,PLBD2;phospholipase B domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen,GO:0016042//lipid catabolic process,GO:0016787//hydrolase activity,-
196472,0,0,0,6,0,54,25,0,0,0,0,0,"FAM71C;family with sequence similarity 71, member C",-,-,-,-
196477,0,0,0,0,0,0,0,0,41,3,0,0,CCER1;coiled-coil glutamate-rich protein 1,-,-,-,-
196483,1,46,0,10,33,0,10,49,13,0,0,0,"FAM86A;family with sequence similarity 86, member A",GO:0005737//cytoplasm,-,-,K03842//N-Glycan biosynthesis;Metabolic pathways;Various types of N-glycan biosynthesis
1965,0,39,1,117,315,16,26,0,52,0,12,155,"EIF2S1;eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa",GO:0016020//membrane;GO:0005844//polysome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006413//translational initiation;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0046777//protein autophosphorylation;GO:0043558//regulation of translational initiation in response to stress,GO:0043022//ribosome binding;GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K03237//Measles;RNA transport;Influenza A;Herpes simplex infection;Protein processing in endoplasmic reticulum;Hepatitis C
196500,45,0,0,0,0,19,8,0,37,0,5,0,PIANP;PILR alpha associated neural protein,GO:0016021//integral component of membrane,-,-,-
196513,7,0,0,0,8,0,21,0,44,0,0,0,DCP1B;decapping mRNA 1B,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol,"GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0010467//gene expression;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0016787//hydrolase activity;GO:0005515//protein binding,K12611//RNA degradation
196527,0,0,0,1,0,0,3,0,61,0,1,0,ANO6;anoctamin 6,GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0034707//chloride channel complex,GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0007596//blood coagulation;GO:0034765//regulation of ion transmembrane transport;GO:0055085//transmembrane transport;GO:0002543//activation of blood coagulation via clotting cascade;GO:0044070//regulation of anion transport;GO:0035630//bone mineralization involved in bone maturation;GO:1902476//chloride transmembrane transport;GO:0002407//dendritic cell chemotaxis;GO:0097045//phosphatidylserine exposure on blood platelet;GO:0017121//phospholipid scrambling;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0006821//chloride transport,GO:0005244//voltage-gated ion channel activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0005227//calcium activated cation channel activity;GO:0017128//phospholipid scramblase activity;GO:0042803//protein homodimerization activity;GO:0005247//voltage-gated chloride channel activity,K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
196528,0,51,1,69,154,33,70,0,50,0,19,0,"ARID2;AT rich interactive domain 2 (ARID, RFX-like)",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006337//nucleosome disassembly;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
1967,0,0,0,28,30,13,0,0,11,0,0,0,"EIF2B1;eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa",GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005737//cytoplasm,GO:0009408//response to heat;GO:0006413//translational initiation;GO:0006412//translation;GO:0010467//gene expression;GO:0043434//response to peptide hormone;GO:0032057//negative regulation of translational initiation in response to stress;GO:0044267//cellular protein metabolic process;GO:0009749//response to glucose;GO:0051716//cellular response to stimulus;GO:0006446//regulation of translational initiation;GO:0014003//oligodendrocyte development;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0043547//positive regulation of GTPase activity,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0030234//enzyme regulator activity;GO:0005525//GTP binding;GO:0003743//translation initiation factor activity;GO:0046523//S-methyl-5-thioribose-1-phosphate isomerase activity;GO:0019003//GDP binding;GO:0005515//protein binding,K03239//Cysteine and methionine metabolism;RNA transport;Metabolic pathways
196740,0,0,0,0,0,9,8,0,55,0,3,34,VSTM4;V-set and transmembrane domain containing 4,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways
196743,0,1,0,0,1,7,0,1,0,0,3,0,PAOX;polyamine oxidase (exo-N4-amino),GO:0005782//peroxisomal matrix,GO:0009447//putrescine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009446//putrescine biosynthetic process;GO:0055114//oxidation-reduction process;GO:1901307//positive regulation of spermidine biosynthetic process;GO:0006596//polyamine biosynthetic process;GO:0046208//spermine catabolic process;GO:0046203//spermidine catabolic process;GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0006805//xenobiotic metabolic process,"GO:0052901//spermine:oxygen oxidoreductase (spermidine-forming) activity;GO:0052902//spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity;GO:0052904//N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0052899//N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0046592//polyamine oxidase activity;GO:0052903//N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity;GO:0005102//receptor binding",K00308//Peroxisome
1968,0,35,3,87,531,24,4,0,19,0,9,0,"EIF2S3;eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006184//GTP catabolic process;GO:0006413//translational initiation;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,"GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding",K03242//RNA transport
196883,0,0,0,0,0,1,0,48,24,1,0,0,ADCY4;adenylate cyclase 4,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006171//cAMP biosynthetic process;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0007202//activation of phospholipase C activity;GO:0007165//signal transduction;GO:0006833//water transport;GO:0034199//activation of protein kinase A activity;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006112//energy reserve metabolic process,GO:0046872//metal ion binding;GO:0004016//adenylate cyclase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K08044//Progesterone-mediated oocyte maturation;Pancreatic secretion;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Purine metabolism;Vascular smooth muscle contraction;Morphine addiction;Oocyte meiosis;Glutamatergic synapse;Taste transduction;Salivary secretion;Dilated cardiomyopathy;Calcium signaling pathway;Retrograde endocannabinoid signaling;Cholinergic synapse;HTLV-I infection;GABAergic synapse;Melanogenesis;Bile secretion;Gastric acid secretion
1969,0,0,0,0,0,0,38,61,0,0,0,753,EPHA2;EPH receptor A2,GO:0009986//cell surface;GO:0032587//ruffle membrane;GO:0031256//leading edge membrane;GO:0005886//plasma membrane;GO:0031258//lamellipodium membrane;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0001570//vasculogenesis;GO:0070848//response to growth factor;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0007275//multicellular organismal development;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0030216//keratinocyte differentiation;GO:0060035//notochord cell development;GO:0048320//axial mesoderm formation;GO:0030316//osteoclast differentiation;GO:0030182//neuron differentiation;GO:0070309//lens fiber cell morphogenesis;GO:0014028//notochord formation;GO:0045765//regulation of angiogenesis;GO:0021915//neural tube development;GO:0032863//activation of Rac GTPase activity;GO:0033598//mammary gland epithelial cell proliferation;GO:0060326//cell chemotaxis;GO:0036342//post-anal tail morphogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0001525//angiogenesis;GO:0010591//regulation of lamellipodium assembly;GO:0043491//protein kinase B signaling;GO:0046849//bone remodeling;GO:0007155//cell adhesion;GO:0001501//skeletal system development;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0051898//negative regulation of protein kinase B signaling;GO:0001649//osteoblast differentiation;GO:0016032//viral process;GO:0016477//cell migration;GO:0043535//regulation of blood vessel endothelial cell migration,GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005003//ephrin receptor activity;GO:0005524//ATP binding;GO:0005515//protein binding,K05103//Axon guidance
196951,0,0,0,0,0,10,0,0,0,0,0,0,"FAM227B;family with sequence similarity 227, member B",-,-,-,-
196968,124,0,0,0,0,23,0,1,35,0,9,0,DNM1P46;DNM1 pseudogene 46,GO:0005874//microtubule,GO:0006184//GTP catabolic process,GO:0003924//GTPase activity,K01528//Synaptic vesicle cycle;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Bacterial invasion of epithelial cells;Endocytosis
196993,0,176,70,55,89,0,57,0,38,0,48,0,CT62;cancer/testis antigen 62,-,-,-,-
196996,156,0,0,0,0,27,22,0,17,136,0,1,GRAMD2;GRAM domain containing 2,GO:0016021//integral component of membrane,-,-,-
197,0,0,0,0,0,0,0,0,4,0,0,0,AHSG;alpha-2-HS-glycoprotein,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,GO:0010951//negative regulation of endopeptidase activity;GO:0001501//skeletal system development;GO:0006907//pinocytosis;GO:0050727//regulation of inflammatory response;GO:0042326//negative regulation of phosphorylation;GO:0006953//acute-phase response;GO:0001503//ossification;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0030502//negative regulation of bone mineralization;GO:0030500//regulation of bone mineralization;GO:0050766//positive regulation of phagocytosis,GO:0019210//kinase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity,-
197021,0,1,49,61,75,11,0,0,35,1,8,302,LCTL;lactase-like,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0005975//carbohydrate metabolic process,"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",K01229//Metabolic pathways;Galactose metabolism;Carbohydrate digestion and absorption
197131,166,13,2,25,92,15,66,75,74,132,14,1,UBR1;ubiquitin protein ligase E3 component n-recognin 1,GO:0000502//proteasome complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol,GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0032007//negative regulation of TOR signaling;GO:0071233//cellular response to leucine,GO:0070728//leucine binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
197135,0,0,0,0,10,12,1,0,22,0,0,0,PATL2;protein associated with topoisomerase II homolog 2 (yeast),GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex,GO:0017148//negative regulation of translation;GO:0010607//negative regulation of cytoplasmic mRNA processing body assembly,GO:0005515//protein binding;GO:0003723//RNA binding,K12617//RNA degradation
197257,0,7,0,0,1,0,6,20,10,44,0,0,LDHD;lactate dehydrogenase D,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0050660//flavin adenine dinucleotide binding;GO:0004458//D-lactate dehydrogenase (cytochrome) activity;GO:0005515//protein binding;GO:0008762//UDP-N-acetylmuramate dehydrogenase activity,K00102//Pyruvate metabolism
197258,0,0,0,0,1,0,83,0,33,0,0,0,FUK;fucokinase,GO:0005737//cytoplasm,GO:0016310//phosphorylation,GO:0050201//fucokinase activity;GO:0005524//ATP binding,K05305//Fructose and mannose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism
197259,2,0,0,0,0,20,0,0,0,0,3,0,MLKL;mixed lineage kinase domain-like,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0070266//necroptotic process;GO:0006468//protein phosphorylation;GO:0070207//protein homotrimerization,GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0005515//protein binding,-
197320,0,0,0,0,0,16,1,0,17,28,0,0,ZNF778;zinc finger protein 778,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
197322,0,0,0,0,31,11,1,40,17,0,0,0,ACSF3;acyl-CoA synthetase family member 3,GO:0005739//mitochondrion,GO:0090410//malonate catabolic process;GO:0006631//fatty acid metabolic process;GO:0006633//fatty acid biosynthetic process,GO:0005524//ATP binding;GO:0016878//acid-thiol ligase activity;GO:0090409//malonyl-CoA synthetase activity,K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
197335,0,0,1,0,8,0,34,2,74,29,0,0,WDR90;WD repeat domain 90,-,-,-,K12602//RNA degradation;K02084//Apoptosis;Alzheimer's disease;Amyotrophic lateral sclerosis (ALS);p53 signaling pathway;Parkinson's disease;Huntington's disease;Legionellosis;Tuberculosis;Small cell lung cancer
197342,0,0,0,0,0,14,0,50,0,0,0,0,EME2;essential meiotic structure-specific endonuclease subunit 2,GO:0005634//nucleus,GO:0006310//DNA recombination;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair,GO:0004519//endonuclease activity;GO:0003677//DNA binding,K10883//Fanconi anemia pathway
197358,61,0,26,60,78,15,12,100,81,0,78,0,"NLRC3;NLR family, CARD domain containing 3",GO:0005737//cytoplasm,GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0042110//T cell activation;GO:0031396//regulation of protein ubiquitination;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032496//response to lipopolysaccharide;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0005524//ATP binding,K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
197370,64,14,0,28,92,13,0,0,1,81,0,0,NSMCE1;non-SMC element 1 homolog (S. cerevisiae),"GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0030915//Smc5-Smc6 complex;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005634//nucleus",GO:0035556//intracellular signal transduction;GO:2001022//positive regulation of response to DNA damage stimulus;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
1974,0,29,15,175,502,0,0,0,0,0,0,0,EIF4A2;eukaryotic translation initiation factor 4A2,GO:0005829//cytosol;GO:0016281//eukaryotic translation initiation factor 4F complex,"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006446//regulation of translational initiation;GO:0016032//viral process;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006413//translational initiation;GO:0006412//translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0019221//cytokine-mediated signaling pathway;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004386//helicase activity;GO:0003743//translation initiation factor activity;GO:0005524//ATP binding,K03257//RNA transport
197407,87,0,0,17,96,26,0,0,35,139,92,0,ZNF48;zinc finger protein 48,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
1977,0,25,0,3,163,0,16,0,16,25,0,0,EIF4E;eukaryotic translation initiation factor 4E,GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0070062//extracellular vesicular exosome;GO:0005845//mRNA cap binding complex;GO:0016442//RISC complex;GO:0010494//cytoplasmic stress granule;GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol;GO:0033391//chromatoid body,"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0006417//regulation of translation;GO:0006412//translation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0045931//positive regulation of mitotic cell cycle;GO:0006406//mRNA export from nucleus;GO:0019221//cytokine-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0044267//cellular protein metabolic process;GO:0030324//lung development;GO:0006413//translational initiation;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle",GO:0000339//RNA cap binding;GO:0003743//translation initiation factor activity;GO:0031370//eukaryotic initiation factor 4G binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K03259//RNA transport;mTOR signaling pathway;Insulin signaling pathway
1978,81,0,1,0,0,0,0,0,0,0,0,0,EIF4EBP1;eukaryotic translation initiation factor 4E binding protein 1,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0045931//positive regulation of mitotic cell cycle;GO:0045947//negative regulation of translational initiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0031929//TOR signaling;GO:0006413//translational initiation;GO:0030324//lung development;GO:0031333//negative regulation of protein complex assembly;GO:0006412//translation;GO:0002931//response to ischemia;GO:0010467//gene expression;GO:0045471//response to ethanol;GO:0044267//cellular protein metabolic process;GO:0008286//insulin receptor signaling pathway,GO:0005515//protein binding;GO:0030371//translation repressor activity;GO:0008190//eukaryotic initiation factor 4E binding,K07205//ErbB signaling pathway;RNA transport;mTOR signaling pathway;Acute myeloid leukemia;Insulin signaling pathway
1979,0,64,0,78,328,0,18,0,53,0,1,0,EIF4EBP2;eukaryotic translation initiation factor 4E binding protein 2,-,GO:0019933//cAMP-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0006412//translation;GO:0045947//negative regulation of translational initiation,GO:0008190//eukaryotic initiation factor 4E binding;GO:0005515//protein binding,K07205//Insulin signaling pathway;Acute myeloid leukemia;mTOR signaling pathway;ErbB signaling pathway;RNA transport
1981,97,88,0,23,62,13,5,101,22,208,10,0,"EIF4G1;eukaryotic translation initiation factor 4 gamma, 1",GO:0016020//membrane;GO:0005829//cytosol;GO:0016281//eukaryotic translation initiation factor 4F complex,"GO:0006412//translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0045471//response to ethanol;GO:0010467//gene expression;GO:0006446//regulation of translational initiation;GO:0008219//cell death;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0030324//lung development;GO:0006413//translational initiation;GO:0008286//insulin receptor signaling pathway;GO:0044267//cellular protein metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0016032//viral process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process","GO:0008190//eukaryotic initiation factor 4E binding;GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding",K03260//RNA transport;Viral myocarditis
1982,0,124,39,224,1031,25,0,2,1,106,0,1,"EIF4G2;eukaryotic translation initiation factor 4 gamma, 2",GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol;GO:0016020//membrane,GO:0008219//cell death;GO:0006446//regulation of translational initiation;GO:0006413//translational initiation;GO:0019221//cytokine-mediated signaling pathway;GO:0007050//cell cycle arrest,"GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding",K03260//RNA transport;Viral myocarditis
1983,0,108,1,104,255,13,9,67,25,0,0,170,EIF5;eukaryotic translation initiation factor 5,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0006412//translation;GO:0006446//regulation of translational initiation;GO:0006413//translational initiation;GO:0006184//GTP catabolic process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression,"GO:0008135//translation factor activity, nucleic acid binding;GO:0044822//poly(A) RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003743//translation initiation factor activity",K03262//RNA transport
1984,146,32,47,11,62,0,1,2,30,0,23,0,EIF5A;eukaryotic translation initiation factor 5A,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005642//annulate lamellae;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005643//nuclear pore,GO:0008612//peptidyl-lysine modification to peptidyl-hypusine;GO:0006915//apoptotic process;GO:0006611//protein export from nucleus;GO:0044267//cellular protein metabolic process;GO:0045901//positive regulation of translational elongation;GO:0006406//mRNA export from nucleus;GO:0008284//positive regulation of cell proliferation;GO:0043687//post-translational protein modification;GO:0006913//nucleocytoplasmic transport;GO:0006452//translational frameshifting;GO:0045905//positive regulation of translational termination,GO:0017070//U6 snRNA binding;GO:0047485//protein N-terminus binding;GO:0003746//translation elongation factor activity;GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
198437,0,0,0,0,0,0,0,0,26,0,0,0,LKAAEAR1;LKAAEAR motif containing 1,-,-,-,-
1990,0,0,0,0,0,13,36,0,0,0,0,0,"CELA1;chymotrypsin-like elastase family, member 1",GO:0005576//extracellular region,GO:0031017//exocrine pancreas development;GO:0042127//regulation of cell proliferation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0009791//post-embryonic development;GO:0061113//pancreas morphogenesis;GO:0035264//multicellular organism growth;GO:0045595//regulation of cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006508//proteolysis,GO:0046872//metal ion binding;GO:0004252//serine-type endopeptidase activity,-
1992,0,0,0,0,0,56,3,0,41,0,0,0,"SERPINB1;serpin peptidase inhibitor, clade B (ovalbumin), member 1",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
199221,0,0,0,0,0,27,0,11,30,0,0,0,DZIP1L;DAZ interacting zinc finger protein 1-like,GO:0005814//centriole;GO:0036064//ciliary basal body,GO:0042384//cilium assembly,GO:0046872//metal ion binding,-
199223,4,0,0,7,0,16,0,25,22,0,0,0,TTC21A;tetratricopeptide repeat domain 21A,-,-,-,-
1993,0,0,0,0,0,0,0,62,18,0,0,0,ELAVL2;ELAV like neuron-specific RNA binding protein 2,-,"GO:0006355//regulation of transcription, DNA-templated",GO:0003730//mRNA 3'-UTR binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
1994,0,0,0,26,62,13,0,0,12,0,0,0,ELAVL1;ELAV like RNA binding protein 1,GO:0005829//cytosol;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045727//positive regulation of translation;GO:0048255//mRNA stabilization;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0010467//gene expression;GO:0007275//multicellular organismal development;GO:2000036//regulation of stem cell maintenance,GO:0044822//poly(A) RNA binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding;GO:0017091//AU-rich element binding;GO:0019901//protein kinase binding;GO:0003729//mRNA binding;GO:0003725//double-stranded RNA binding;GO:0003723//RNA binding,-
1995,1,0,0,0,0,0,58,0,11,0,12,0,ELAVL3;ELAV like neuron-specific RNA binding protein 3,-,GO:0030154//cell differentiation;GO:0007399//nervous system development,GO:0017091//AU-rich element binding;GO:0000166//nucleotide binding,-
1996,1,0,0,0,0,0,0,0,51,0,13,0,ELAVL4;ELAV like neuron-specific RNA binding protein 4,-,GO:0006397//mRNA processing;GO:0006396//RNA processing,GO:0003730//mRNA 3'-UTR binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0017091//AU-rich element binding,-
199675,0,0,0,0,0,0,12,0,0,0,8,0,MCEMP1;mast cell-expressed membrane protein 1,GO:0016021//integral component of membrane,-,-,-
199692,0,30,0,10,10,0,33,0,27,0,7,0,ZNF627;zinc finger protein 627,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
199699,0,0,0,0,0,16,53,0,10,0,0,0,"DAND5;DAN domain family member 5, BMP antagonist",GO:0005576//extracellular region,GO:0038101//sequestering of nodal from receptor via nodal binding;GO:0030514//negative regulation of BMP signaling pathway;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0061371//determination of heart left/right asymmetry;GO:0003281//ventricular septum development;GO:0003283//atrial septum development;GO:1900108//negative regulation of nodal signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0016015//morphogen activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
1997,0,43,0,10,85,6,14,0,0,0,0,0,ELF1;E74-like factor 1 (ets domain transcription factor),GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0001817//regulation of cytokine production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
199704,0,0,0,0,6,16,43,0,16,0,0,0,ZNF585A;zinc finger protein 585A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003676//nucleic acid binding,-
199713,0,0,0,0,0,0,0,40,40,0,0,0,"NLRP7;NLR family, pyrin domain containing 7",-,-,GO:0005524//ATP binding,K12800//Influenza A;NOD-like receptor signaling pathway;Pertussis
199720,0,0,0,0,0,0,0,0,8,0,9,0,GGN;gametogenetin,GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus,GO:0030154//cell differentiation;GO:0007276//gamete generation;GO:0007275//multicellular organismal development;GO:0008104//protein localization;GO:0007283//spermatogenesis,GO:0046983//protein dimerization activity,-
199731,0,0,1,0,30,13,19,0,0,0,0,0,CADM4;cell adhesion molecule 4,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007155//cell adhesion,-,-
199745,0,0,0,0,0,0,14,0,0,0,0,0,THAP8;THAP domain containing 8,-,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,K00943//Two-component system;Metabolic pathways;One carbon pool by folate;Pyrimidine metabolism
199746,0,0,0,0,0,0,0,74,0,0,0,0,U2AF1L4;U2 small nuclear RNA auxiliary factor 1-like 4,GO:0016607//nuclear speck;GO:0005681//spliceosomal complex,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0046872//metal ion binding,K12836//Spliceosome;Shigellosis
199777,0,40,0,0,7,0,17,0,18,0,16,0,ZNF626;zinc finger protein 626,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
199786,1,0,0,0,0,0,0,0,48,0,7,0,"FAM129C;family with sequence similarity 129, member C",-,-,-,-
1998,0,9,0,0,53,0,0,0,0,0,39,0,ELF2;E74-like factor 2 (ets domain transcription factor),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
199800,0,0,0,0,0,0,22,0,32,0,0,0,ADM5;adrenomedullin 5 (putative),GO:0005576//extracellular region,-,-,-
199857,0,0,0,0,31,14,0,0,30,116,0,0,"ALG14;ALG14, UDP-N-acetylglucosaminyltransferase subunit",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process,-,K07441//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
199870,0,0,3,0,0,0,0,0,15,0,0,0,"FAM76A;family with sequence similarity 76, member A",-,-,-,K11447//Transcriptional misregulation in cancer;K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
1999,0,0,0,3,17,0,37,0,39,0,11,0,"ELF3;E74-like factor 3 (ets domain transcription factor, epithelial-specific )",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030198//extracellular matrix organization;GO:0060056//mammary gland involution;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0008544//epidermis development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030855//epithelial cell differentiation;GO:0001824//blastocyst development;GO:0007275//multicellular organismal development",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003713//transcription coactivator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
199920,0,0,0,0,0,50,0,0,34,66,0,0,C1orf168;chromosome 1 open reading frame 168,-,-,-,-
199953,0,0,0,0,0,23,9,0,17,0,11,0,TMEM201;transmembrane protein 201,GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane,GO:0010761//fibroblast migration;GO:0007097//nuclear migration,GO:0005521//lamin binding;GO:0051015//actin filament binding,-
199964,0,0,0,0,0,0,0,47,28,0,0,0,TMEM61;transmembrane protein 61,GO:0016021//integral component of membrane,-,-,-
199974,3,0,0,0,0,43,0,0,21,0,0,0,"CYP4Z1;cytochrome P450, family 4, subfamily Z, polypeptide 1",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0070330//aromatase activity,K07428//Serotonergic synapse
199990,30,182,141,146,288,0,78,293,96,0,470,289,C1orf86;chromosome 1 open reading frame 86,GO:0005634//nucleus;GO:0030054//cell junction;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0043240//Fanconi anaemia nuclear complex,GO:0019985//translesion synthesis;GO:0036297//interstrand cross-link repair;GO:0006974//cellular response to DNA damage stimulus,GO:0043130//ubiquitin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0031593//polyubiquitin binding;GO:0070530//K63-linked polyubiquitin binding,K06069//Type II diabetes mellitus;Endocytosis;Insulin signaling pathway;Tight junction;Chemokine signaling pathway;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
2,0,0,0,0,0,8,0,0,105,111,11,0,A2M;alpha-2-macroglobulin,GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0031093//platelet alpha granule lumen,"GO:0048863//stem cell differentiation;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:0002576//platelet degranulation;GO:0022617//extracellular matrix disassembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0030198//extracellular matrix organization;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation",GO:0019966//interleukin-1 binding;GO:0019899//enzyme binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019959//interleukin-8 binding;GO:0005102//receptor binding;GO:0019838//growth factor binding;GO:0002020//protease binding;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0043120//tumor necrosis factor binding,K03910//Complement and coagulation cascades
20,0,0,0,0,1,29,9,147,53,0,0,293,"ABCA2;ATP-binding cassette, sub-family A (ABC1), member 2",GO:0005765//lysosomal membrane;GO:0005768//endosome;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0010008//endosome membrane;GO:0005815//microtubule organizing center;GO:0005764//lysosome,GO:0048545//response to steroid hormone;GO:0055085//transmembrane transport;GO:0042632//cholesterol homeostasis;GO:0006810//transport;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0032383//regulation of intracellular cholesterol transport;GO:0006629//lipid metabolic process;GO:0042493//response to drug,"GO:0016887//ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0000166//nucleotide binding;GO:0005524//ATP binding",K05642//Lysosome;ABC transporters
2000,0,0,0,0,0,23,0,0,15,3,0,0,ELF4;E74-like factor 4 (ets domain transcription factor),GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016605//PML body,"GO:0001787//natural killer cell proliferation;GO:0001866//NK T cell proliferation;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005515//protein binding,-
200008,0,0,0,0,0,0,0,0,44,0,0,0,CDCP2;CUB domain containing protein 2,GO:0005576//extracellular region,-,-,K14616//Vitamin digestion and absorption
200010,0,0,0,0,10,0,20,51,22,0,1,3,"SLC5A9;solute carrier family 5 (sodium/sugar cotransporter), member 9",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0055085//transmembrane transport;GO:0006814//sodium ion transport,GO:0005215//transporter activity,-
200014,163,51,1,6,35,20,51,0,25,32,0,0,CC2D1B;coiled-coil and C2 domain containing 1B,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
200030,2,0,0,0,2,2,10,6,14,0,9,0,"NBPF11;neuroblastoma breakpoint family, member 11",GO:0005737//cytoplasm,-,-,K12478//Tuberculosis;Phagosome;Endocytosis
200035,0,0,0,5,0,0,0,0,15,13,5,0,NUDT17;nudix (nucleoside diphosphate linked moiety X)-type motif 17,-,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,-
200081,0,25,45,0,13,34,15,0,12,0,9,0,TXLNA;taxilin alpha,GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0016020//membrane,GO:0006887//exocytosis;GO:0008283//cell proliferation;GO:0042113//B cell activation,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0019905//syntaxin binding;GO:0030372//high molecular weight B cell growth factor receptor binding,K06106//Shigellosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction;K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
2001,0,1,0,0,31,0,0,0,0,0,1,0,ELF5;E74-like factor 5 (ets domain transcription factor),GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007398//ectoderm development;GO:0060644//mammary gland epithelial cell differentiation,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
200132,0,0,0,0,0,0,39,0,12,0,0,0,TCTEX1D1;Tctex1 domain containing 1,-,-,-,-
200150,135,0,0,0,0,0,0,6,40,140,0,0,"PLD5;phospholipase D family, member 5",GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
200159,0,0,0,0,0,0,0,0,20,0,0,0,C1orf100;chromosome 1 open reading frame 100,-,-,-,-
200162,112,0,0,0,0,28,52,1,68,7,19,0,SPAG17;sperm associated antigen 17,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005730//nucleolus;GO:0036126//sperm flagellum,-,-,-
200186,0,34,0,7,0,47,0,1,1,8,0,0,CRTC2;CREB regulated transcription coactivator 2,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006094//gluconeogenesis;GO:0006351//transcription, DNA-templated;GO:0051289//protein homotetramerization;GO:0016032//viral process;GO:0042593//glucose homeostasis;GO:0032793//positive regulation of CREB transcription factor activity",GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding,K15309//HTLV-I infection
200197,0,0,0,0,0,0,21,114,21,0,4,0,TMEM51-AS1;TMEM51 antisense RNA 1,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
2002,0,56,0,0,0,0,0,0,0,0,0,0,"ELK1;ELK1, member of ETS oncogene family",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0002756//MyD88-independent toll-like receptor signaling pathway",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K04375//Endometrial cancer;MAPK signaling pathway;Prion diseases;Leishmaniasis;Focal adhesion;ErbB signaling pathway;HTLV-I infection;Insulin signaling pathway;GnRH signaling pathway
200205,0,0,0,1,27,0,29,0,35,0,21,0,"IBA57;IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)",GO:0005739//mitochondrion,GO:0032259//methylation;GO:0006546//glycine catabolic process;GO:0006783//heme biosynthetic process,GO:0004047//aminomethyltransferase activity;GO:0044822//poly(A) RNA binding,"K06980//One carbon pool by folate;Metabolic pathways;Nitrogen metabolism;Glycine, serine and threonine metabolism"
200232,30,0,0,0,0,0,0,71,0,0,0,0,"FAM209A;family with sequence similarity 209, member A",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,-,-
2003,0,0,0,0,0,13,0,0,26,0,0,0,"ELK2AP;ELK2A, member of ETS oncogene family, pseudogene",-,-,-,K04375//GnRH signaling pathway;HTLV-I infection;Insulin signaling pathway;ErbB signaling pathway;Focal adhesion;MAPK signaling pathway;Endometrial cancer;Prion diseases;Leishmaniasis;K06856//Allograft rejection;Staphylococcus aureus infection;Hematopoietic cell lineage;Viral myocarditis;Systemic lupus erythematosus;Natural killer cell mediated cytotoxicity;Amoebiasis;Epstein-Barr virus infection;Phagosome;Autoimmune thyroid disease;Rheumatoid arthritis;NF-kappa B signaling pathway;Primary immunodeficiency;Intestinal immune network for IgA production;African trypanosomiasis;Tuberculosis;Leishmaniasis;Asthma;Measles;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Calcium signaling pathway;Dilated cardiomyopathy;Transcriptional misregulation in cancer;Fc gamma R-mediated phagocytosis
200312,160,0,0,0,0,1,27,0,0,156,0,0,RNF215;ring finger protein 215,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
200316,0,0,1,0,23,22,0,0,28,0,13,0,"APOBEC3F;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F",GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0030529//ribonucleoprotein complex,GO:0045071//negative regulation of viral genome replication;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0002230//positive regulation of defense response to virus by host;GO:0070383//DNA cytosine deamination;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0009972//cytidine deamination;GO:0048525//negative regulation of viral process;GO:0010529//negative regulation of transposition;GO:0016553//base conversion or substitution editing;GO:0080111//DNA demethylation,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding;GO:0004126//cytidine deaminase activity,K01500//Microbial metabolism in diverse environments;Atrazine degradation
200350,0,0,0,0,0,38,1,0,23,0,7,0,FOXD4L1;forkhead box D4-like 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
200373,0,0,0,0,0,1,21,0,62,0,0,0,CFAP221;cilia and flagella associated protein 221,GO:0005929//cilium,GO:0003341//cilium movement;GO:0060271//cilium morphogenesis,GO:0005516//calmodulin binding,-
2004,0,0,25,0,43,29,0,0,16,0,0,0,"ELK3;ELK3, ETS-domain protein (SRF accessory protein 2)",GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0042060//wound healing;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0001525//angiogenesis",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0032422//purine-rich negative regulatory element binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
200403,103,0,1,0,0,37,0,0,64,0,36,0,VWA3B;von Willebrand factor A domain containing 3B,-,-,-,-
200407,0,0,0,0,0,9,0,0,41,0,3,0,CREG2;cellular repressor of E1A-stimulated genes 2,GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity;GO:0010181//FMN binding,K06453//Chagas disease (American trypanosomiasis);Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway
200420,0,0,0,0,0,0,0,63,42,0,0,0,ALMS1P;Alstrom syndrome 1 pseudogene,-,GO:0016197//endosomal transport;GO:0051492//regulation of stress fiber assembly,-,-
200424,0,0,0,25,33,29,24,0,74,0,4,0,TET3;tet methylcytosine dioxygenase 3,GO:0005737//cytoplasm;GO:0001939//female pronucleus;GO:0001940//male pronucleus,GO:0006493//protein O-linked glycosylation;GO:0080111//DNA demethylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0080182//histone H3-K4 trimethylation;GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0070579//methylcytosine dioxygenase activity,-
2005,1,129,77,107,807,0,42,165,60,1,27,0,"ELK4;ELK4, ETS-domain protein (SRF accessory protein 1)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070932//histone H3 deacetylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation,GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003682//chromatin binding;GO:0001047//core promoter binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity,K04376//Transcriptional misregulation in cancer;MAPK signaling pathway;HTLV-I infection
200504,0,0,0,0,0,0,0,0,1,0,0,0,GKN2;gastrokine 2,GO:0005576//extracellular region,-,-,-
200523,0,0,0,0,0,0,0,0,36,0,8,0,TEX37;testis expressed 37,GO:0005634//nucleus,-,-,-
200539,0,0,0,0,0,35,8,0,13,147,13,0,ANKRD23;ankyrin repeat domain 23,GO:0014704//intercalated disc;GO:0031674//I band;GO:0005634//nucleus,GO:0009612//response to mechanical stimulus;GO:0006631//fatty acid metabolic process,GO:0031432//titin binding,-
200558,0,28,0,4,10,0,14,0,27,0,0,0,APLF;aprataxin and PNKP like factor,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0035861//site of double-strand break;GO:0005634//nucleus,"GO:0051106//positive regulation of DNA ligation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000012//single strand break repair;GO:0006302//double-strand break repair;GO:0045191//regulation of isotype switching;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006974//cellular response to DNA damage stimulus",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0000166//nucleotide binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity,-
200576,0,94,0,81,250,33,14,1,45,0,5,0,"PIKFYVE;phosphoinositide kinase, FYVE finger containing",GO:0048471//perinuclear region of cytoplasm;GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0012506//vesicle membrane;GO:0031901//early endosome membrane;GO:0031410//cytoplasmic vesicle;GO:0005911//cell-cell junction;GO:0010008//endosome membrane;GO:0045121//membrane raft;GO:0000139//Golgi membrane,"GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0042147//retrograde transport, endosome to Golgi;GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0035556//intracellular signal transduction;GO:0044267//cellular protein metabolic process;GO:0034504//protein localization to nucleus;GO:0032288//myelin assembly;GO:0006898//receptor-mediated endocytosis","GO:0005515//protein binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0008270//zinc ion binding;GO:0000285//1-phosphatidylinositol-3-phosphate 5-kinase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity;GO:0005524//ATP binding",K00889//Endocytosis;Metabolic pathways;Regulation of actin cytoskeleton;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Focal adhesion;Fc gamma R-mediated phagocytosis;K00921//Inositol phosphate metabolism;Phagosome;Regulation of actin cytoskeleton;Phosphatidylinositol signaling system
2006,1,281,51,103,118,25,61,160,22,0,117,0,ELN;elastin,GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0071953//elastic fiber;GO:0005578//proteinaceous extracellular matrix,GO:0009887//organ morphogenesis;GO:0008283//cell proliferation;GO:0043149//stress fiber assembly;GO:0007519//skeletal muscle tissue development;GO:0001974//blood vessel remodeling;GO:0008015//blood circulation;GO:0030198//extracellular matrix organization;GO:0007585//respiratory gaseous exchange;GO:0022617//extracellular matrix disassembly;GO:0030833//regulation of actin filament polymerization,GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0030023//extracellular matrix constituent conferring elasticity;GO:0050840//extracellular matrix binding,K14211//Protein digestion and absorption
200634,0,63,107,78,44,0,0,0,28,0,72,0,KRTCAP3;keratinocyte associated protein 3,GO:0016021//integral component of membrane,-,-,-
200726,0,0,0,0,0,0,29,0,0,0,0,0,LOC200726;hCG1657980,-,-,-,-
200728,0,0,0,0,0,0,0,0,13,0,0,0,TMEM17;transmembrane protein 17,GO:0036038//TCTN-B9D complex;GO:0060170//ciliary membrane;GO:0035869//ciliary transition zone;GO:0016021//integral component of membrane,GO:0007224//smoothened signaling pathway;GO:0042384//cilium assembly,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
200734,102,0,0,24,2,3,4,0,0,0,0,0,"SPRED2;sprouty-related, EVH1 domain containing 2",GO:0030658//transport vesicle membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus,"GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0000188//inactivation of MAPK activity;GO:0090311//regulation of protein deacetylation;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0007275//multicellular organismal development",GO:0005173//stem cell factor receptor binding;GO:0030291//protein serine/threonine kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0005515//protein binding,K04703//Jak-STAT signaling pathway
200765,0,0,1,6,0,16,0,0,0,0,0,0,TIGD1;tigger transposable element derived 1,GO:0005634//nucleus,-,GO:0003677//DNA binding,K04514//Pathogenic Escherichia coli infection;Focal adhesion;Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Chemokine signaling pathway;Axon guidance;Salmonella infection
200810,0,0,0,3,7,23,28,0,0,0,6,0,"ALG1L;ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like",-,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",K03842//N-Glycan biosynthesis;Various types of N-glycan biosynthesis;Metabolic pathways
200844,89,0,0,0,0,0,0,0,30,1,0,0,C3orf67;chromosome 3 open reading frame 67,-,-,-,-
200845,0,0,0,0,4,0,12,0,36,0,0,0,KCTD6;potassium channel tetramerization domain containing 6,-,GO:0051260//protein homooligomerization,GO:0030506//ankyrin binding,-
200879,0,17,0,0,0,0,0,0,42,0,0,0,"LIPH;lipase, member H",GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0016042//lipid catabolic process,GO:0008201//heparin binding;GO:0004620//phospholipase activity,"K01066//Limonene and pinene degradation;Naphthalene degradation;Metabolic pathways;Tropane, piperidine and pyridine alkaloid biosynthesis;Aminobenzoate degradation;Toluene degradation;Polycyclic aromatic hydrocarbon degradation;Chlorocyclohexane and chlorobenzene degradation;Microbial metabolism in diverse environments;Histidine metabolism;Bisphenol degradation"
200894,130,0,0,18,19,1,0,0,0,0,0,0,ARL13B;ADP-ribosylation factor-like 13B,GO:0005929//cilium;GO:0072372//primary cilium;GO:0005622//intracellular;GO:0060170//ciliary membrane,GO:0035058//nonmotile primary cilium assembly;GO:0007224//smoothened signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0021830//interneuron migration from the subpallium to the cortex;GO:0070986//left/right axis specification;GO:0021532//neural tube patterning;GO:0042384//cilium assembly;GO:0021943//formation of radial glial scaffolds;GO:0001947//heart looping;GO:0009953//dorsal/ventral pattern formation,GO:0005525//GTP binding;GO:0005515//protein binding,-
200895,95,27,39,57,53,0,51,19,25,0,63,0,DHFRL1;dihydrofolate reductase-like 1,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0046105//thymidine biosynthetic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0046653//tetrahydrofolate metabolic process;GO:0006545//glycine biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0055114//oxidation-reduction process;GO:0009165//nucleotide biosynthetic process,GO:0004146//dihydrofolate reductase activity;GO:0050661//NADP binding;GO:0003729//mRNA binding,K00287//Biosynthesis of secondary metabolites;Folate biosynthesis;Nicotinate and nicotinamide metabolism;Terpenoid backbone biosynthesis;Metabolic pathways;ABC transporters;One carbon pool by folate
2009,0,0,0,0,0,14,54,7,40,67,2,0,EML1;echinoderm microtubule associated protein like 1,GO:0005829//cytosol;GO:0005875//microtubule associated complex;GO:0097431//mitotic spindle pole;GO:0005874//microtubule;GO:1990023//mitotic spindle midzone;GO:0048471//perinuclear region of cytoplasm,GO:0007405//neuroblast proliferation;GO:0007420//brain development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007052//mitotic spindle organization;GO:0000226//microtubule cytoskeleton organization,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0005509//calcium ion binding;GO:0015631//tubulin binding,-
200909,0,0,0,0,0,0,0,0,25,0,0,0,"HTR3D;5-hydroxytryptamine (serotonin) receptor 3D, ionotropic",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport,GO:0005230//extracellular ligand-gated ion channel activity,K04819//Serotonergic synapse
200916,0,0,0,8,0,0,0,0,0,0,0,0,RPL22L1;ribosomal protein L22-like 1,GO:0005840//ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K02891//Ribosome
200931,0,0,0,4,30,0,20,0,0,0,25,0,"SLC51A;solute carrier family 51, alpha subunit",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043234//protein complex,GO:0015721//bile acid and bile salt transport;GO:0006810//transport,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005215//transporter activity,K14360//Bile secretion
200933,0,24,0,30,29,2,62,0,15,0,13,0,FBXO45;F-box protein 45,GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane,GO:0016567//protein ubiquitination;GO:0001764//neuron migration;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021960//anterior commissure morphogenesis;GO:0006974//cellular response to DNA damage stimulus;GO:0021957//corticospinal tract morphogenesis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0021800//cerebral cortex tangential migration,GO:0005515//protein binding,-
200942,82,0,1,0,1,0,20,0,0,82,10,0,KLHDC8B;kelch domain containing 8B,GO:0005737//cytoplasm,-,-,-
200958,0,0,0,0,0,0,20,0,11,0,0,0,"MUC20;mucin 20, cell surface associated",GO:0016324//apical plasma membrane;GO:0009925//basal plasma membrane;GO:0005576//extracellular region;GO:0031528//microvillus membrane;GO:0005796//Golgi lumen,GO:0051260//protein homooligomerization;GO:0000187//activation of MAPK activity;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0044267//cellular protein metabolic process,-,"K10955//Vibrio cholerae infection;Amoebiasis;K07515//Biosynthesis of unsaturated fatty acids;Fatty acid metabolism;Lysine degradation;Valine, leucine and isoleucine degradation;Metabolic pathways;beta-Alanine metabolism;Fatty acid elongation;Propanoate metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites;Butanoate metabolism;K03006//Herpes simplex infection;Huntington's disease;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;K13908//Salivary secretion;K13911//Salivary secretion"
200959,0,0,0,0,0,29,23,0,59,0,0,0,"GABRR3;gamma-aminobutyric acid (GABA) A receptor, rho 3",GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0055085//transmembrane transport,GO:0019904//protein domain specific binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0004890//GABA-A receptor activity,K05190//Nicotine addiction;Morphine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
2010,0,0,0,8,5,0,0,0,4,0,0,0,EMD;emerin,GO:0005637//nuclear inner membrane;GO:0005874//microtubule;GO:0005640//nuclear outer membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0031965//nuclear membrane,GO:0071363//cellular response to growth factor stimulus;GO:0007084//mitotic nuclear envelope reassembly;GO:0048147//negative regulation of fibroblast proliferation;GO:0000278//mitotic cell cycle;GO:0006936//muscle contraction;GO:0035414//negative regulation of catenin import into nucleus;GO:0007517//muscle organ development;GO:0046827//positive regulation of protein export from nucleus;GO:0035914//skeletal muscle cell differentiation;GO:0007077//mitotic nuclear envelope disassembly;GO:0060828//regulation of canonical Wnt signaling pathway,GO:0048487//beta-tubulin binding;GO:0005515//protein binding;GO:0003779//actin binding,K12569//Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
2011,73,44,3,22,33,56,0,59,51,118,49,0,MARK2;MAP/microtubule affinity-regulating kinase 2,GO:0005634//nucleus;GO:0005884//actin filament;GO:0045180//basal cortex;GO:0005739//mitochondrion;GO:0097427//microtubule bundle;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0001764//neuron migration;GO:0050770//regulation of axonogenesis;GO:0006468//protein phosphorylation;GO:0000422//mitochondrion degradation;GO:0035556//intracellular signal transduction;GO:0051646//mitochondrion localization;GO:0032147//activation of protein kinase activity;GO:0018107//peptidyl-threonine phosphorylation;GO:0030010//establishment of cell polarity;GO:0051493//regulation of cytoskeleton organization;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0016055//Wnt signaling pathway,GO:0008289//lipid binding;GO:0005524//ATP binding;GO:0050321//tau-protein kinase activity;GO:0000287//magnesium ion binding;GO:0030295//protein kinase activator activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
201134,0,0,0,8,10,36,2,83,11,0,0,0,CEP112;centrosomal protein 112kDa,GO:0060077//inhibitory synapse;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005886//plasma membrane,GO:0097120//receptor localization to synapse,-,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K04514//Salmonella infection;Chemokine signaling pathway;Axon guidance;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Wnt signaling pathway;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Pathogenic Escherichia coli infection
201140,0,0,0,0,0,0,0,0,45,0,0,0,DHRS7C;dehydrogenase/reductase (SDR family) member 7C,GO:0014801//longitudinal sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0005576//extracellular region,GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0055114//oxidation-reduction process,GO:0004745//retinol dehydrogenase activity,-
201158,0,0,0,0,0,0,0,0,9,0,0,0,TVP23C;trans-golgi network vesicle protein 23 homolog C (S. cerevisiae),GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
201161,90,0,0,0,15,2,0,10,0,0,0,0,CENPV;centromere protein V,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0051233//spindle midzone,GO:0032467//positive regulation of cytokinesis;GO:0007067//mitotic nuclear division;GO:0033044//regulation of chromosome organization;GO:0031508//pericentric heterochromatin assembly;GO:0001667//ameboidal cell migration,GO:0016846//carbon-sulfur lyase activity,-
201163,0,0,0,1,12,15,69,0,38,0,9,0,FLCN;folliculin,GO:0044291//cell-cell contact zone;GO:0005886//plasma membrane;GO:0030496//midbody;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:2000506//negative regulation of energy homeostasis;GO:0032007//negative regulation of TOR signaling;GO:0030097//hemopoiesis;GO:0010823//negative regulation of mitochondrion organization;GO:1900181//negative regulation of protein localization to nucleus;GO:0043065//positive regulation of apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0032006//regulation of TOR signaling;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032008//positive regulation of TOR signaling;GO:0032465//regulation of cytokinesis;GO:0035065//regulation of histone acetylation;GO:0045785//positive regulation of cell adhesion;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035024//negative regulation of Rho protein signal transduction;GO:0030336//negative regulation of cell migration;GO:0001932//regulation of protein phosphorylation;GO:0030308//negative regulation of cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression;GO:1901723//negative regulation of cell proliferation involved in kidney development;GO:0001701//in utero embryonic development;GO:2001170//negative regulation of ATP biosynthetic process;GO:0010629//negative regulation of gene expression;GO:2000973//regulation of pro-B cell differentiation;GO:0031929//TOR signaling;GO:0007043//cell-cell junction assembly,GO:0005515//protein binding;GO:0032403//protein complex binding,K09594//Renal cell carcinoma
201164,0,0,0,0,0,4,0,1,28,101,11,0,"PLD6;phospholipase D family, member 6",GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane,GO:0006644//phospholipid metabolic process;GO:0008053//mitochondrial fusion;GO:0046474//glycerophospholipid biosynthetic process;GO:0007286//spermatid development;GO:0044281//small molecule metabolic process;GO:0034587//piRNA metabolic process;GO:0030719//P granule organization;GO:0043046//DNA methylation involved in gamete generation;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007126//meiotic nuclear division;GO:0016042//lipid catabolic process,GO:0004519//endonuclease activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0035755//cardiolipin hydrolase activity,K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
201176,4,0,1,0,0,1,30,0,1,6,0,0,ARHGAP27;Rho GTPase activating protein 27,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005622//intracellular,GO:0006898//receptor-mediated endocytosis;GO:0032855//positive regulation of Rac GTPase activity;GO:0007165//signal transduction;GO:0043089//positive regulation of Cdc42 GTPase activity,GO:0030675//Rac GTPase activator activity;GO:0017124//SH3 domain binding,K04450//Epstein-Barr virus infection;Amphetamine addiction;MAPK signaling pathway;Alcoholism;Influenza A;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;K05732//Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Focal adhesion;K08878//Pathways in cancer;Chronic myeloid leukemia
201181,0,0,0,0,13,4,0,0,11,0,0,0,ZNF385C;zinc finger protein 385C,GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K06062//HTLV-I infection;Notch signaling pathway
201191,0,0,0,0,9,19,0,0,16,0,0,0,SAMD14;sterile alpha motif domain containing 14,-,-,-,-
2012,0,0,0,0,1,0,0,0,26,0,3,0,EMP1;epithelial membrane protein 1,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development;GO:0008544//epidermis development;GO:0016049//cell growth;GO:0008283//cell proliferation,-,K08341//GABAergic synapse;Regulation of autophagy;K06087//Cell adhesion molecules (CAMs);Tight junction;Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
201229,152,27,0,6,0,0,0,0,19,0,0,0,LYRM9;LYR motif containing 9,-,-,-,-
201232,0,0,0,0,0,6,0,29,13,0,0,0,"SLC16A13;solute carrier family 16, member 13",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
201243,0,0,2,0,0,0,0,0,9,0,0,0,C17orf74;chromosome 17 open reading frame 74,GO:0016021//integral component of membrane,-,-,-
201254,0,0,0,0,1,0,1,1,0,0,0,0,STRA13;stimulated by retinoic acid 13,GO:0043240//Fanconi anaemia nuclear complex;GO:0000777//condensed chromosome kinetochore;GO:0071821//FANCM-MHF complex,GO:0031398//positive regulation of protein ubiquitination;GO:0051382//kinetochore assembly;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0000712//resolution of meiotic recombination intermediates;GO:0031297//replication fork processing,GO:0003690//double-stranded DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding,K15360//Fanconi anemia pathway
201255,0,83,55,27,78,0,17,368,39,31,164,0,LRRC45;leucine rich repeat containing 45,GO:0005813//centrosome,-,-,K10165//Tuberculosis;NOD-like receptor signaling pathway;Shigellosis
201266,0,0,0,0,8,0,0,40,25,0,0,0,"SLC39A11;solute carrier family 39, member 11",GO:0016021//integral component of membrane,GO:0006829//zinc ion transport;GO:0055085//transmembrane transport,GO:0046873//metal ion transmembrane transporter activity,-
201283,0,0,0,13,0,0,10,0,5,0,0,0,AMZ2P1;archaelysin family metallopeptidase 2 pseudogene 1,-,-,-,-
201292,0,0,0,0,4,0,0,54,0,0,3,0,TRIM65;tripartite motif containing 65,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
201294,0,0,0,0,12,18,99,77,54,0,5,284,UNC13D;unc-13 homolog D (C. elegans),GO:0055037//recycling endosome;GO:0005764//lysosome;GO:0070382//exocytic vesicle;GO:0005770//late endosome;GO:0016020//membrane,GO:0002432//granuloma formation;GO:0045921//positive regulation of exocytosis;GO:0002467//germinal center formation;GO:0043320//natural killer cell degranulation;GO:0051607//defense response to virus;GO:0043304//regulation of mast cell degranulation;GO:0006909//phagocytosis,GO:0005515//protein binding,K15621//Transcriptional misregulation in cancer
201299,0,0,0,0,0,2,0,0,4,0,0,0,RDM1;RAD52 motif containing 1,GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0016605//PML body;GO:0005730//nucleolus,GO:0006281//DNA repair;GO:0006310//DNA recombination,GO:0000166//nucleotide binding;GO:0003677//DNA binding;GO:0003723//RNA binding,-
2013,0,0,1,5,8,0,29,0,3,0,13,0,EMP2;epithelial membrane protein 2,GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0008283//cell proliferation;GO:0001954//positive regulation of cell-matrix adhesion;GO:2001046//positive regulation of integrin-mediated signaling pathway,GO:0005178//integrin binding,K11447//Transcriptional misregulation in cancer;K08341//GABAergic synapse;Regulation of autophagy;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
201305,0,0,28,0,0,0,0,0,38,0,7,0,SPNS3;spinster homolog 3 (Drosophila),GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006869//lipid transport,-,K06258//ECM-receptor interaction
2014,0,0,0,0,0,0,2,0,0,0,7,0,EMP3;epithelial membrane protein 3,GO:0016021//integral component of membrane,GO:0016049//cell growth;GO:0008285//negative regulation of cell proliferation,-,-
201456,0,0,0,0,0,10,0,48,5,0,0,0,FBXO15;F-box protein 15,GO:0019005//SCF ubiquitin ligase complex,-,-,-
201475,0,0,0,3,18,0,0,0,0,0,7,0,"RAB12;RAB12, member RAS oncogene family",GO:0055038//recycling endosome membrane;GO:0030141//secretory granule;GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0005764//lysosome,GO:0007264//small GTPase mediated signal transduction;GO:0044257//cellular protein catabolic process;GO:0008333//endosome to lysosome transport;GO:0015031//protein transport,GO:0005525//GTP binding;GO:0019003//GDP binding,-
2015,100,0,0,0,0,31,0,0,6,324,14,0,"EMR1;egf-like module containing, mucin-like, hormone receptor-like 1",GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane,GO:0007155//cell adhesion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0005509//calcium ion binding,-
201501,0,0,0,0,0,24,0,1,14,150,16,0,ZBTB7C;zinc finger and BTB domain containing 7C,-,-,GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
201514,0,59,0,6,41,0,33,1,8,0,39,0,ZNF584;zinc finger protein 584,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
201516,0,0,0,0,0,0,0,67,50,0,0,155,ZSCAN4;zinc finger and SCAN domain containing 4,"GO:0000784//nuclear chromosome, telomeric region","GO:0006351//transcription, DNA-templated;GO:0010833//telomere maintenance via telomere lengthening;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
201562,0,0,0,0,0,0,0,0,7,0,0,0,"PTPLB;protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006633//fatty acid biosynthetic process,GO:0005515//protein binding;GO:0016829//lyase activity,K10703//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
201595,72,0,0,9,36,10,10,1,48,1,15,544,"STT3B;STT3B, subunit of the oligosaccharyltransferase complex (catalytic)",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex,GO:0043686//co-translational protein modification;GO:0006516//glycoprotein catabolic process;GO:0043687//post-translational protein modification;GO:0006986//response to unfolded protein;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity,K07151//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis;Protein processing in endoplasmic reticulum
2016,0,0,0,0,0,0,0,0,15,182,0,0,EMX1;empty spiracles homeobox 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0009791//post-embryonic development;GO:0001701//in utero embryonic development;GO:0042493//response to drug;GO:0021895//cerebral cortex neuron differentiation;GO:0048854//brain morphogenesis;GO:1990138//neuron projection extension;GO:0021796//cerebral cortex regionalization",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
201625,97,0,0,0,0,19,58,0,108,302,1,231,"DNAH12;dynein, axonemal, heavy chain 12",GO:0005929//cilium;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0030286//dynein complex,GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,K10408//Huntington's disease
201626,0,1,1,0,45,0,0,7,45,0,0,0,PDE12;phosphodiesterase 12,GO:0005759//mitochondrial matrix,"GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0006397//mRNA processing",GO:0004535//poly(A)-specific ribonuclease activity;GO:0046872//metal ion binding,K12603//RNA degradation
201627,99,0,0,0,13,0,32,0,23,0,0,0,DENND6A;DENN/MADD domain containing 6A,GO:0055037//recycling endosome;GO:0005737//cytoplasm,GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
201633,60,0,0,0,0,15,11,29,0,109,5,0,TIGIT;T cell immunoreceptor with Ig and ITIM domains,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0032695//negative regulation of interleukin-12 production;GO:0032733//positive regulation of interleukin-10 production;GO:0050868//negative regulation of T cell activation,GO:0005102//receptor binding;GO:0005515//protein binding,-
201651,0,0,0,0,0,63,30,0,11,0,0,0,AADACP1;arylacetamide deacetylase pseudogene 1,-,-,-,-
2017,0,47,4,26,87,12,24,149,16,0,13,0,CTTN;cortactin,GO:0005925//focal adhesion;GO:1990023//mitotic spindle midzone;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043197//dendritic spine;GO:0030027//lamellipodium;GO:0070062//extracellular vesicular exosome;GO:0001726//ruffle,GO:2001237//negative regulation of extrinsic apoptotic signaling pathway,GO:0005515//protein binding,K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
201725,0,0,0,0,0,13,0,0,0,0,0,0,C4orf46;chromosome 4 open reading frame 46,-,-,-,-
201780,0,0,0,0,0,0,46,0,0,0,0,0,"SLC10A4;solute carrier family 10, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:0015721//bile acid and bile salt transport,GO:0008508//bile acid:sodium symporter activity,-
201798,0,0,0,0,0,0,0,0,4,0,1,0,TIGD4;tigger transposable element derived 4,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
201799,0,0,0,0,0,0,19,0,35,0,10,0,TMEM154;transmembrane protein 154,GO:0016021//integral component of membrane,-,-,-
201895,88,63,2,109,189,4,8,1,0,0,0,0,SMIM14;small integral membrane protein 14,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2019,0,0,0,0,0,5,0,0,16,0,0,0,EN1;engrailed homeobox 1,GO:0005634//nucleus;GO:0016020//membrane,GO:0009953//dorsal/ventral pattern formation;GO:0001501//skeletal system development;GO:0009653//anatomical structure morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0035264//multicellular organism growth;GO:0030917//midbrain-hindbrain boundary development;GO:0030902//hindbrain development;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030901//midbrain development;GO:0048666//neuron development;GO:0043473//pigmentation;GO:0042220//response to cocaine,GO:0043565//sequence-specific DNA binding,-
201931,29,0,0,6,37,72,0,0,8,0,0,0,TMEM192;transmembrane protein 192,GO:0005765//lysosomal membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005764//lysosome,-,GO:0042803//protein homodimerization activity,K11447//Transcriptional misregulation in cancer
201965,0,35,0,61,113,0,0,45,7,158,0,0,RWDD4;RWD domain containing 4,-,-,-,-
202,0,201,2,311,771,12,29,0,35,0,0,221,AIM1;absent in melanoma 1,-,-,GO:0030246//carbohydrate binding,K01886//ABC transporters;Aminoacyl-tRNA biosynthesis;Metabolic pathways;Ribosome;K04257//Olfactory transduction
2020,0,0,0,0,0,0,0,0,48,0,2,0,EN2;engrailed homeobox 2,GO:0016020//membrane;GO:0005634//nucleus,GO:0048666//neuron development;GO:0007275//multicellular organismal development;GO:0030902//hindbrain development;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding,-
202018,40,0,0,0,0,12,27,0,20,0,0,0,TAPT1;transmembrane anterior posterior transformation 1,GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0009791//post-embryonic development;GO:0048706//embryonic skeletal system development;GO:0001701//in utero embryonic development,GO:0016520//growth hormone-releasing hormone receptor activity,-
202020,0,0,0,0,0,20,0,44,11,0,0,0,TAPT1-AS1;TAPT1 antisense RNA 1 (head to head),-,-,-,K02971//Ribosome
202051,0,59,0,15,93,0,29,69,3,64,119,0,SPATA24;spermatogenesis associated 24,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation",GO:0003677//DNA binding;GO:0042803//protein homodimerization activity,K12478//Endocytosis;Phagosome;Tuberculosis
202052,0,0,0,0,0,18,0,0,18,2,15,0,"DNAJC18;DnaJ (Hsp40) homolog, subfamily C, member 18",GO:0016021//integral component of membrane,-,-,-
2021,0,290,47,327,339,27,0,168,58,1,449,2,ENDOG;endonuclease G,GO:0005739//mitochondrion,GO:0001701//in utero embryonic development;GO:0034612//response to tumor necrosis factor;GO:0046677//response to antibiotic;GO:0043065//positive regulation of apoptotic process;GO:0006309//apoptotic DNA fragmentation;GO:0006310//DNA recombination,GO:0046872//metal ion binding;GO:0004519//endonuclease activity;GO:0004518//nuclease activity;GO:0003676//nucleic acid binding,K01173//Apoptosis
202134,0,0,8,0,0,0,47,0,4,0,0,0,"FAM153B;family with sequence similarity 153, member B",-,-,-,-
202151,0,33,0,21,53,19,20,0,66,0,0,0,RANBP3L;RAN binding protein 3-like,-,GO:0046907//intracellular transport,-,K15304//HTLV-I infection
202181,0,62,30,39,0,0,0,0,19,0,42,0,LOC202181;SUMO-interacting motifs containing 1 pseudogene,-,-,-,"K07515//Fatty acid elongation;Propanoate metabolism;Metabolic pathways;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Biosynthesis of unsaturated fatty acids;Lysine degradation;Fatty acid metabolism;Butanoate metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites;K12826//Spliceosome"
2022,0,0,0,0,29,7,0,170,99,0,31,0,ENG;endoglin,GO:0005634//nucleus;GO:0070022//transforming growth factor beta receptor homodimeric complex;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0072563//endothelial microparticle;GO:0009986//cell surface,"GO:0022617//extracellular matrix disassembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001666//response to hypoxia;GO:0071559//response to transforming growth factor beta;GO:0071260//cellular response to mechanical stimulus;GO:0060348//bone development;GO:0003273//cell migration involved in endocardial cushion formation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0031960//response to corticosteroid;GO:0042325//regulation of phosphorylation;GO:0001570//vasculogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0001947//heart looping;GO:0048745//smooth muscle tissue development;GO:0042060//wound healing;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0016477//cell migration;GO:0030513//positive regulation of BMP signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0001569//patterning of blood vessels;GO:0070483//detection of hypoxia;GO:0048844//artery morphogenesis;GO:0030155//regulation of cell adhesion;GO:0022009//central nervous system vasculogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0048870//cell motility;GO:0031953//negative regulation of protein autophosphorylation;GO:0036273//response to statin;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0070278//extracellular matrix constituent secretion;GO:0060326//cell chemotaxis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001300//chronological cell aging;GO:0032967//positive regulation of collagen biosynthetic process;GO:0035556//intracellular signal transduction;GO:0048845//venous blood vessel morphogenesis;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression","GO:0005534//galactose binding;GO:0005072//transforming growth factor beta receptor, cytoplasmic mediator activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0048185//activin binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005539//glycosaminoglycan binding;GO:0004888//transmembrane signaling receptor activity;GO:0050431//transforming growth factor beta binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0005114//type II transforming growth factor beta receptor binding",-
202243,0,0,0,0,8,0,0,0,0,0,0,0,CCDC125;coiled-coil domain containing 125,GO:0005737//cytoplasm,-,-,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2023,6,9,26,11,67,17,9,0,40,0,14,67,"ENO1;enolase 1, (alpha)",GO:0005829//cytosol;GO:0005615//extracellular space;GO:0031430//M band;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0000015//phosphopyruvate hydratase complex;GO:0016020//membrane;GO:0005737//cytoplasm,"GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0005975//carbohydrate metabolic process;GO:0009615//response to virus;GO:0030308//negative regulation of cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006094//gluconeogenesis",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0000287//magnesium ion binding;GO:0003714//transcription corepressor activity;GO:0004634//phosphopyruvate hydratase activity,K01689//Microbial metabolism in diverse environments;Metabolic pathways;RNA degradation;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Methane metabolism
202333,0,0,0,0,39,16,0,64,120,0,0,0,CMYA5;cardiomyopathy associated 5,GO:0031430//M band;GO:0048471//perinuclear region of cytoplasm;GO:0043034//costamere,GO:0014733//regulation of skeletal muscle adaptation;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0032513//negative regulation of protein phosphatase type 2B activity,GO:0042802//identical protein binding;GO:0005515//protein binding,K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Calcium signaling pathway;Gastric acid secretion
202374,85,0,0,0,0,36,44,0,58,0,0,0,STK32A;serine/threonine kinase 32A,-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity,-
202559,0,0,0,0,0,0,27,0,17,178,0,0,"KHDRBS2;KH domain containing, RNA binding, signal transduction associated 2",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0017124//SH3 domain binding;GO:0008266//poly(U) RNA binding;GO:0008143//poly(A) binding;GO:0042169//SH2 domain binding,-
2026,0,0,0,0,0,23,0,0,7,77,14,0,"ENO2;enolase 2 (gamma, neuronal)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0043204//perikaryon;GO:0000015//phosphopyruvate hydratase complex;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0001917//photoreceptor inner segment,GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006094//gluconeogenesis,GO:0004634//phosphopyruvate hydratase activity;GO:0000287//magnesium ion binding,K01689//Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Methane metabolism;Microbial metabolism in diverse environments;Metabolic pathways;RNA degradation
2027,0,0,0,0,0,0,32,138,19,0,0,0,"ENO3;enolase 3 (beta, muscle)",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0000015//phosphopyruvate hydratase complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006094//gluconeogenesis;GO:0043403//skeletal muscle tissue regeneration;GO:0005975//carbohydrate metabolic process;GO:0042493//response to drug;GO:0007568//aging;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004634//phosphopyruvate hydratase activity;GO:0000287//magnesium ion binding,K01689//Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Metabolic pathways;RNA degradation
2028,0,0,0,0,0,0,80,0,17,0,0,0,ENPEP;glutamyl aminopeptidase (aminopeptidase A),GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0045177//apical part of cell;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border,GO:0001525//angiogenesis;GO:0032835//glomerulus development;GO:0002005//angiotensin catabolic process in blood;GO:0007267//cell-cell signaling;GO:0016477//cell migration;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0006508//proteolysis;GO:0002003//angiotensin maturation;GO:0044267//cellular protein metabolic process;GO:0008283//cell proliferation,GO:0070006//metalloaminopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity,K11141//Renin-angiotensin system
202865,0,0,0,0,0,0,0,0,11,0,4,0,C7orf33;chromosome 7 open reading frame 33,-,-,-,-
2029,0,25,0,44,89,12,21,0,15,0,5,0,ENSA;endosulfine alpha,GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0050796//regulation of insulin secretion;GO:0043086//negative regulation of catalytic activity;GO:0007584//response to nutrient;GO:0006810//transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0009749//response to glucose;GO:0050790//regulation of catalytic activity;GO:0007067//mitotic nuclear division,GO:0004864//protein phosphatase inhibitor activity;GO:0005102//receptor binding;GO:0019870//potassium channel inhibitor activity;GO:0051721//protein phosphatase 2A binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0008200//ion channel inhibitor activity;GO:0019212//phosphatase inhibitor activity,-
202915,6,70,15,58,153,37,44,244,30,0,72,8,TMEM184A;transmembrane protein 184A,GO:0031901//early endosome membrane;GO:0016021//integral component of membrane,GO:0018992//germ-line sex determination;GO:0032880//regulation of protein localization;GO:0051046//regulation of secretion,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K14360//Bile secretion
203,83,0,0,0,16,16,12,0,24,0,12,0,AK1;adenylate kinase 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0036126//sperm flagellum;GO:0005737//cytoplasm;GO:0001520//outer dense fiber,GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0046034//ATP metabolic process;GO:0006172//ADP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0046033//AMP metabolic process;GO:0007050//cell cycle arrest;GO:0044281//small molecule metabolic process,GO:0004017//adenylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
2030,0,0,0,0,0,0,20,59,55,0,3,0,"SLC29A1;solute carrier family 29 (equilibrative nucleoside transporter), member 1",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0071456//cellular response to hypoxia;GO:0007595//lactation;GO:0030431//sleep;GO:0055085//transmembrane transport;GO:0071333//cellular response to glucose stimulus;GO:1901642//nucleoside transmembrane transport;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0006139//nucleobase-containing compound metabolic process,GO:0005337//nucleoside transmembrane transporter activity,K15014//Alcoholism
203054,0,0,1,0,21,26,30,0,25,0,10,56,ADCK5;aarF domain containing kinase 5,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity,-
203062,0,0,1,0,0,0,6,0,20,0,0,0,TSNARE1;t-SNARE domain containing 1,GO:0031201//SNARE complex;GO:0016021//integral component of membrane,GO:0006886//intracellular protein transport;GO:0016079//synaptic vesicle exocytosis,GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity,-
203068,0,0,0,0,0,0,1,38,0,0,0,0,"TUBB;tubulin, beta class I",GO:0044297//cell body;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005641//nuclear envelope lumen,GO:0009987//cellular process;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0007017//microtubule-based process;GO:0006928//cellular component movement;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051301//cell division;GO:0051225//spindle assembly;GO:0042267//natural killer cell mediated cytotoxicity,GO:0032403//protein complex binding;GO:0005200//structural constituent of cytoskeleton;GO:0042288//MHC class I protein binding;GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0005198//structural molecule activity;GO:0032794//GTPase activating protein binding;GO:0003924//GTPase activity;GO:0005515//protein binding,K07375//Phagosome;Gap junction;Pathogenic Escherichia coli infection
203074,0,0,0,0,0,0,0,1,3,0,8,124,"PRSS55;protease, serine, 55",GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01324//Complement and coagulation cascades
203076,0,0,0,0,0,0,29,0,0,0,0,0,C8orf74;chromosome 8 open reading frame 74,-,-,GO:0005515//protein binding,-
203100,59,0,0,0,0,28,0,0,27,0,0,308,HTRA4;HtrA serine peptidase 4,GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0001558//regulation of cell growth;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0004175//endopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding,-
203102,0,0,0,0,0,31,0,0,65,0,0,0,ADAM32;ADAM metallopeptidase domain 32,GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
203111,0,0,0,0,0,0,33,0,20,0,0,0,ERICH5;glutamate-rich 5,-,-,-,-
203190,0,0,0,0,4,7,0,0,20,0,5,14,"LGI3;leucine-rich repeat LGI family, member 3",GO:0005576//extracellular region;GO:0030054//cell junction;GO:0008021//synaptic vesicle;GO:0043005//neuron projection,GO:0008152//metabolic process;GO:0006887//exocytosis;GO:0017157//regulation of exocytosis,GO:0003824//catalytic activity,K06839//Axon guidance
203197,162,0,0,6,15,0,2,0,8,0,12,0,C9orf91;chromosome 9 open reading frame 91,GO:0016021//integral component of membrane,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
203228,84,0,0,22,49,0,0,0,37,0,0,0,C9orf72;chromosome 9 open reading frame 72,GO:0005615//extracellular space;GO:0005768//endosome;GO:0031410//cytoplasmic vesicle;GO:0005764//lysosome;GO:0005634//nucleus;GO:0005776//autophagic vacuole,GO:0006897//endocytosis;GO:0006914//autophagy;GO:0008219//cell death,GO:0017137//Rab GTPase binding;GO:0005515//protein binding,-
203238,114,0,0,0,0,9,31,0,25,212,0,0,CCDC171;coiled-coil domain containing 171,-,-,-,-
203245,0,0,0,0,1,0,0,0,0,0,0,0,NAIF1;nuclear apoptosis inducing factor 1,GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005634//nucleus,GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0030308//negative regulation of cell growth,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
203259,123,0,0,0,15,19,16,0,0,0,1,0,"FAM219A;family with sequence similarity 219, member A",-,-,-,-
203260,0,0,0,0,0,10,0,0,0,0,0,0,CCDC107;coiled-coil domain containing 107,GO:0016021//integral component of membrane,-,-,-
203286,90,26,0,0,34,14,30,0,45,0,19,0,ANKS6;ankyrin repeat and sterile alpha motif domain containing 6,GO:0005929//cilium;GO:0005737//cytoplasm,-,GO:0042803//protein homodimerization activity,-
2033,0,0,3,9,85,12,54,78,107,0,18,368,EP300;E1A binding protein p300,GO:0005730//nucleolus;GO:0000123//histone acetyltransferase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,"GO:0007623//circadian rhythm;GO:0043923//positive regulation by host of viral transcription;GO:0007519//skeletal muscle tissue development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060765//regulation of androgen receptor signaling pathway;GO:0016032//viral process;GO:0043967//histone H4 acetylation;GO:0009887//organ morphogenesis;GO:0051726//regulation of cell cycle;GO:0032092//positive regulation of protein binding;GO:0006351//transcription, DNA-templated;GO:0007507//heart development;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0007399//nervous system development;GO:0043627//response to estrogen;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0090043//regulation of tubulin deacetylation;GO:0006915//apoptotic process;GO:0030324//lung development;GO:0001666//response to hypoxia;GO:0007219//Notch signaling pathway;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043969//histone H2B acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0018393//internal peptidyl-lysine acetylation;GO:0071456//cellular response to hypoxia;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006475//internal protein amino acid acetylation","GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0016746//transferase activity, transferring acyl groups;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0097157//pre-mRNA intronic binding;GO:0001047//core promoter binding;GO:0003682//chromatin binding;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0031490//chromatin DNA binding;GO:0050681//androgen receptor binding;GO:0016407//acetyltransferase activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0033613//activating transcription factor binding;GO:0002039//p53 binding;GO:0008013//beta-catenin binding;GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding",K04498//Melanogenesis;Notch signaling pathway;TGF-beta signaling pathway;Jak-STAT signaling pathway;HTLV-I infection;Adherens junction;Renal cell carcinoma;Epstein-Barr virus infection;Cell cycle;Herpes simplex infection;Wnt signaling pathway;Prostate cancer;Tuberculosis;Influenza A;Long-term potentiation;Pathways in cancer;Huntington's disease
203328,0,0,0,0,0,0,18,0,13,0,0,0,SUSD3;sushi domain containing 3,GO:0016021//integral component of membrane,-,-,-
2034,103,0,0,1,61,0,1,0,35,0,8,0,EPAS1;endothelial PAS domain protein 1,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,GO:0042415//norepinephrine metabolic process;GO:0030218//erythrocyte differentiation;GO:0043129//surfactant homeostasis;GO:0048469//cell maturation;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0001525//angiogenesis;GO:0071456//cellular response to hypoxia;GO:0001974//blood vessel remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0001666//response to hypoxia;GO:0030324//lung development;GO:0002027//regulation of heart rate;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0048625//myoblast fate commitment;GO:0007165//signal transduction;GO:0001892//embryonic placenta development;GO:0007601//visual perception;GO:0007005//mitochondrion organization,GO:0008134//transcription factor binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0035035//histone acetyltransferase binding,K09095//Pathways in cancer;Renal cell carcinoma
203413,0,0,0,0,0,0,0,0,8,0,0,0,CT83;cancer/testis antigen 83,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K00134//Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Metabolic pathways;Alzheimer's disease;Microbial metabolism in diverse environments
203427,0,0,0,0,40,19,0,22,23,0,0,0,"SLC25A43;solute carrier family 25, member 43",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport,-,-
203430,0,0,0,0,0,14,0,0,21,0,0,0,"ZCCHC5;zinc finger, CCHC domain containing 5",-,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K06237//ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;Protein digestion and absorption;Amoebiasis;Focal adhesion
203447,0,0,0,6,50,8,2,0,80,0,7,0,NRK;Nik related kinase,-,GO:0007256//activation of JNKK activity;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0007567//parturition,GO:0005083//small GTPase regulator activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K04407//MAPK signaling pathway
2035,0,51,1,25,203,0,0,0,80,0,0,0,EPB41;erythrocyte membrane protein band 4.1,GO:0043234//protein complex;GO:0005634//nucleus;GO:0019898//extrinsic component of membrane;GO:0008091//spectrin;GO:0030863//cortical cytoskeleton;GO:0014731//spectrin-associated cytoskeleton;GO:0005886//plasma membrane,GO:0032092//positive regulation of protein binding;GO:0030036//actin cytoskeleton organization;GO:0030866//cortical actin cytoskeleton organization;GO:0008015//blood circulation,GO:0030507//spectrin binding;GO:0005516//calmodulin binding;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding,K06107//Tight junction
203522,0,0,0,0,0,20,0,0,38,168,15,0,DDX26B;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B,-,-,-,-
203523,101,0,0,4,13,6,47,0,12,0,17,0,ZNF449;zinc finger protein 449,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
203547,0,1,0,40,130,13,0,0,40,0,0,0,VMA21;VMA21 vacuolar H+-ATPase homolog (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0005764//lysosome;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0030127//COPII vesicle coat,GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
203562,0,0,0,5,12,0,0,0,0,21,0,0,TMEM31;transmembrane protein 31,GO:0016021//integral component of membrane,-,-,-
2036,227,0,0,7,58,46,63,20,80,0,7,1,EPB41L1;erythrocyte membrane protein band 4.1-like 1,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0019898//extrinsic component of membrane,GO:0007268//synaptic transmission;GO:0030866//cortical actin cytoskeleton organization,GO:0005198//structural molecule activity;GO:0003779//actin binding,K06107//Tight junction
2037,0,0,0,0,0,14,79,0,29,54,1,0,EPB41L2;erythrocyte membrane protein band 4.1-like 2,GO:0019898//extrinsic component of membrane;GO:0070062//extracellular vesicular exosome;GO:0008180//COP9 signalosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0008091//spectrin,GO:0030866//cortical actin cytoskeleton organization,GO:0042731//PH domain binding;GO:0003779//actin binding;GO:0005198//structural molecule activity,K06107//Tight junction
2038,0,0,0,0,0,0,0,0,17,0,5,25,EPB42;erythrocyte membrane protein band 4.2,GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0030863//cortical cytoskeleton,GO:0000902//cell morphogenesis;GO:0043249//erythrocyte maturation;GO:0020027//hemoglobin metabolic process;GO:0018149//peptide cross-linking;GO:0055072//iron ion homeostasis;GO:0008360//regulation of cell shape;GO:0048536//spleen development,GO:0005200//structural constituent of cytoskeleton;GO:0005524//ATP binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding,K05625//Huntington's disease
203859,70,1,0,0,14,32,43,0,69,0,6,0,ANO5;anoctamin 5,GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0005789//endoplasmic reticulum membrane,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006821//chloride transport;GO:0055085//transmembrane transport,GO:0005229//intracellular calcium activated chloride channel activity,-
2039,127,34,1,4,45,0,0,11,1,0,0,0,DMTN;dematin actin binding protein,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0031095//platelet dense tubular network membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0014731//spectrin-associated cytoskeleton;GO:0005884//actin filament;GO:0048471//perinuclear region of cytoplasm;GO:0031253//cell projection membrane,GO:0051017//actin filament bundle assembly;GO:0010763//positive regulation of fibroblast migration;GO:0030194//positive regulation of blood coagulation;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0010812//negative regulation of cell-substrate adhesion;GO:0051489//regulation of filopodium assembly;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0071320//cellular response to cAMP;GO:0048821//erythrocyte development;GO:0051895//negative regulation of focal adhesion assembly;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0090315//negative regulation of protein targeting to membrane;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0006461//protein complex assembly;GO:0010591//regulation of lamellipodium assembly;GO:0071277//cellular response to calcium ion;GO:0008360//regulation of cell shape;GO:0090303//positive regulation of wound healing;GO:0032956//regulation of actin cytoskeleton organization;GO:1901731//positive regulation of platelet aggregation;GO:0007010//cytoskeleton organization;GO:0051693//actin filament capping;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0070560//protein secretion by platelet;GO:0090527//actin filament reorganization;GO:0030036//actin cytoskeleton organization,GO:0005515//protein binding;GO:0043621//protein self-association;GO:0005102//receptor binding;GO:0030507//spectrin binding;GO:0003779//actin binding,K07520//Axon guidance
204,0,0,0,4,72,0,0,0,39,0,0,0,AK2;adenylate kinase 2,GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0097226//sperm mitochondrial sheath;GO:0005829//cytosol,GO:0046060//dATP metabolic process;GO:0006172//ADP biosynthetic process;GO:0007420//brain development;GO:0006119//oxidative phosphorylation;GO:0001889//liver development;GO:0044281//small molecule metabolic process;GO:0097066//response to thyroid hormone;GO:0046939//nucleotide phosphorylation;GO:0015949//nucleobase-containing small molecule interconversion;GO:0046033//AMP metabolic process,GO:0005524//ATP binding;GO:0004017//adenylate kinase activity,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2040,0,0,0,0,0,15,31,0,18,0,12,0,STOM;stomatin,GO:0005856//cytoskeleton;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0042470//melanosome;GO:0016020//membrane;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space,GO:0051260//protein homooligomerization,GO:0042803//protein homodimerization activity,K01539//Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K03364//Cell cycle;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
204010,0,0,0,0,0,0,18,0,0,0,1,0,RPSAP52;ribosomal protein SA pseudogene 52,-,-,-,K02998//Ribosome
2041,40,0,0,0,0,23,0,0,12,0,0,0,EPHA1;EPH receptor A1,GO:0005887//integral component of plasma membrane,GO:0030335//positive regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030336//negative regulation of cell migration;GO:0001954//positive regulation of cell-matrix adhesion;GO:0032862//activation of Rho GTPase activity;GO:0007166//cell surface receptor signaling pathway;GO:0048013//ephrin receptor signaling pathway;GO:0032314//regulation of Rac GTPase activity;GO:0046777//protein autophosphorylation;GO:0001525//angiogenesis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0006469//negative regulation of protein kinase activity;GO:0045766//positive regulation of angiogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0008284//positive regulation of cell proliferation,GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0005005//transmembrane-ephrin receptor activity,K05102//Axon guidance
2042,0,0,0,0,0,7,0,3,85,0,7,0,EPHA3;EPH receptor A3,GO:0005887//integral component of plasma membrane;GO:0005769//early endosome;GO:0005576//extracellular region,GO:0051893//regulation of focal adhesion assembly;GO:0097156//fasciculation of motor neuron axon;GO:0071300//cellular response to retinoic acid;GO:0097155//fasciculation of sensory neuron axon;GO:0032319//regulation of Rho GTPase activity;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032956//regulation of actin cytoskeleton organization;GO:0007155//cell adhesion;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0016477//cell migration;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0048013//ephrin receptor signaling pathway;GO:0010976//positive regulation of neuron projection development,GO:0005524//ATP binding;GO:0005004//GPI-linked ephrin receptor activity;GO:0005515//protein binding,K05104//Axon guidance
204219,57,0,0,0,8,0,56,1,20,120,0,0,CERS3;ceramide synthase 3,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0030216//keratinocyte differentiation;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process,GO:0050291//sphingosine N-acyltransferase activity;GO:0003677//DNA binding,K04710//Sphingolipid metabolism;Metabolic pathways
2043,0,0,23,0,0,0,47,0,13,0,9,0,EPHA4;EPH receptor A4,GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0045211//postsynaptic membrane;GO:0031901//early endosome membrane;GO:0031594//neuromuscular junction;GO:0030175//filopodium;GO:0030425//dendrite;GO:0009986//cell surface;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0044295//axonal growth cone;GO:0043679//axon terminus;GO:0014069//postsynaptic density;GO:0030424//axon;GO:0043204//perikaryon;GO:0005887//integral component of plasma membrane,GO:0007628//adult walking behavior;GO:0032317//regulation of Rap GTPase activity;GO:0048681//negative regulation of axon regeneration;GO:0050770//regulation of axonogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0061001//regulation of dendritic spine morphogenesis;GO:0008045//motor neuron axon guidance;GO:0097156//fasciculation of motor neuron axon;GO:0048013//ephrin receptor signaling pathway;GO:0008347//glial cell migration;GO:0007155//cell adhesion;GO:0097155//fasciculation of sensory neuron axon;GO:0043507//positive regulation of JUN kinase activity;GO:0046777//protein autophosphorylation;GO:0032314//regulation of Rac GTPase activity;GO:0021957//corticospinal tract morphogenesis;GO:0048710//regulation of astrocyte differentiation;GO:2001108//positive regulation of Rho guanyl-nucleotide exchange factor activity;GO:0050775//positive regulation of dendrite morphogenesis,GO:0042731//PH domain binding;GO:0005515//protein binding;GO:0005005//transmembrane-ephrin receptor activity;GO:0097161//DH domain binding;GO:0005524//ATP binding;GO:0046875//ephrin receptor binding;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0005004//GPI-linked ephrin receptor activity,K05105//Axon guidance
2044,0,19,1,94,56,0,28,2,91,268,97,0,EPHA5;EPH receptor A5,GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0009897//external side of plasma membrane,GO:0032793//positive regulation of CREB transcription factor activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0019933//cAMP-mediated signaling;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0032314//regulation of Rac GTPase activity;GO:0048013//ephrin receptor signaling pathway;GO:0021766//hippocampus development;GO:0048666//neuron development;GO:0051964//negative regulation of synapse assembly,GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0005004//GPI-linked ephrin receptor activity;GO:0005005//transmembrane-ephrin receptor activity,K05106//Axon guidance
204474,52,0,0,0,11,44,0,0,18,0,10,0,"PDILT;protein disulfide isomerase-like, testis expressed",GO:0005783//endoplasmic reticulum,GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0007275//multicellular organismal development;GO:0045454//cell redox homeostasis;GO:0016477//cell migration;GO:0034976//response to endoplasmic reticulum stress;GO:0007286//spermatid development;GO:0006457//protein folding,GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0003756//protein disulfide isomerase activity,K09580//Protein processing in endoplasmic reticulum
2045,0,0,0,7,0,8,0,0,51,0,5,0,EPHA7;EPH receptor A7,GO:0005887//integral component of plasma membrane;GO:0043025//neuronal cell body;GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0031594//neuromuscular junction,GO:0022407//regulation of cell-cell adhesion;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0048013//ephrin receptor signaling pathway;GO:0031290//retinal ganglion cell axon guidance;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0048755//branching morphogenesis of a nerve;GO:0016310//phosphorylation;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031952//regulation of protein autophosphorylation;GO:0050919//negative chemotaxis;GO:0043525//positive regulation of neuron apoptotic process,GO:0005004//GPI-linked ephrin receptor activity;GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0046875//ephrin receptor binding;GO:0005524//ATP binding;GO:0045499//chemorepellent activity;GO:0004713//protein tyrosine kinase activity,K05108//Axon guidance
2046,0,0,0,0,0,0,14,0,96,0,0,0,EPHA8;EPH receptor A8,GO:0005887//integral component of plasma membrane;GO:0031901//early endosome membrane;GO:0043005//neuron projection,GO:0030155//regulation of cell adhesion;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0007411//axon guidance;GO:0006929//substrate-dependent cell migration;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0007155//cell adhesion;GO:0043410//positive regulation of MAPK cascade;GO:0031175//neuron projection development;GO:0016322//neuron remodeling;GO:0048013//ephrin receptor signaling pathway;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0005004//GPI-linked ephrin receptor activity,K05109//Axon guidance
2047,0,0,0,0,0,36,0,0,38,0,0,233,EPHB1;EPH receptor B1,GO:0005887//integral component of plasma membrane;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0030424//axon;GO:0031901//early endosome membrane;GO:0045121//membrane raft,GO:0051965//positive regulation of synapse assembly;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0046777//protein autophosphorylation;GO:0031589//cell-substrate adhesion;GO:0021631//optic nerve morphogenesis;GO:0022008//neurogenesis;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0031290//retinal ganglion cell axon guidance;GO:0060326//cell chemotaxis;GO:0048013//ephrin receptor signaling pathway;GO:0001525//angiogenesis;GO:0030010//establishment of cell polarity;GO:0007411//axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048593//camera-type eye morphogenesis;GO:0060997//dendritic spine morphogenesis;GO:0046328//regulation of JNK cascade;GO:0060996//dendritic spine development;GO:0061351//neural precursor cell proliferation,GO:0005515//protein binding;GO:0005005//transmembrane-ephrin receptor activity;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity,K05110//Axon guidance
2048,93,0,0,0,0,34,0,62,56,0,6,32,EPHB2;EPH receptor B2,GO:0030425//dendrite;GO:0030424//axon;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane,GO:0051965//positive regulation of synapse assembly;GO:0001655//urogenital system development;GO:0016310//phosphorylation;GO:0021631//optic nerve morphogenesis;GO:0007399//nervous system development;GO:0071679//commissural neuron axon guidance;GO:0031290//retinal ganglion cell axon guidance;GO:0050878//regulation of body fluid levels;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0007413//axonal fasciculation;GO:0042472//inner ear morphogenesis;GO:0048593//camera-type eye morphogenesis;GO:0060021//palate development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0050771//negative regulation of axonogenesis;GO:0007612//learning;GO:0021952//central nervous system projection neuron axonogenesis;GO:0007411//axon guidance;GO:0060997//dendritic spine morphogenesis;GO:0022038//corpus callosum development;GO:0060996//dendritic spine development;GO:0048170//positive regulation of long-term neuronal synaptic plasticity,GO:0005005//transmembrane-ephrin receptor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008046//axon guidance receptor activity;GO:0004713//protein tyrosine kinase activity;GO:0005102//receptor binding,K05111//Axon guidance
204801,0,6,0,0,0,9,0,0,4,0,0,0,"NLRP11;NLR family, pyrin domain containing 11",-,GO:0055114//oxidation-reduction process,"GO:0044822//poly(A) RNA binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen;GO:0005524//ATP binding",K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
204851,0,2,63,58,49,35,0,0,80,0,3,0,HIPK1;homeodomain interacting protein kinase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0016605//PML body,"GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0048596//embryonic camera-type eye morphogenesis;GO:0007224//smoothened signaling pathway;GO:0060216//definitive hemopoiesis;GO:0009952//anterior/posterior pattern specification;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006468//protein phosphorylation;GO:0010842//retina layer formation;GO:0030182//neuron differentiation;GO:0061072//iris morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0060235//lens induction in camera-type eye;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0008284//positive regulation of cell proliferation;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0072577//endothelial cell apoptotic process;GO:0006351//transcription, DNA-templated;GO:0001654//eye development",GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
2049,30,0,0,0,0,0,29,36,29,0,0,0,EPHB3;EPH receptor B3,GO:0005887//integral component of plasma membrane;GO:0030425//dendrite,GO:0048013//ephrin receptor signaling pathway;GO:0001525//angiogenesis;GO:0031290//retinal ganglion cell axon guidance;GO:0007413//axonal fasciculation;GO:0048538//thymus development;GO:0060997//dendritic spine morphogenesis;GO:0022038//corpus callosum development;GO:0060021//palate development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0050770//regulation of axonogenesis;GO:0007411//axon guidance;GO:0021952//central nervous system projection neuron axonogenesis;GO:0060996//dendritic spine development;GO:0022407//regulation of cell-cell adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0001655//urogenital system development;GO:0046777//protein autophosphorylation;GO:0032314//regulation of Rac GTPase activity;GO:0051965//positive regulation of synapse assembly;GO:0016477//cell migration;GO:0048546//digestive tract morphogenesis;GO:0043088//regulation of Cdc42 GTPase activity,GO:0005003//ephrin receptor activity;GO:0008046//axon guidance receptor activity;GO:0005524//ATP binding,K05112//Axon guidance
204962,0,0,0,0,0,18,0,37,38,0,0,0,"SLC44A5;solute carrier family 44, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0055085//transmembrane transport;GO:0044281//small molecule metabolic process;GO:0006656//phosphatidylcholine biosynthetic process,-,-
205,13,0,0,78,171,2,13,0,19,0,0,0,AK4;adenylate kinase 4,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0046033//AMP metabolic process;GO:0046039//GTP metabolic process;GO:0042493//response to drug;GO:0001889//liver development;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0046034//ATP metabolic process;GO:0006172//ADP biosynthetic process;GO:0007420//brain development,GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005525//GTP binding;GO:0046899//nucleoside triphosphate adenylate kinase activity;GO:0004017//adenylate kinase activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
2050,0,0,0,0,1,11,40,0,0,0,32,0,EPHB4;EPH receptor B4,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0048013//ephrin receptor signaling pathway;GO:0046777//protein autophosphorylation;GO:0001525//angiogenesis;GO:0007155//cell adhesion;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0003007//heart morphogenesis;GO:0002042//cell migration involved in sprouting angiogenesis,GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding,K05113//Axon guidance
2051,22,0,0,0,0,39,13,25,50,105,26,0,EPHB6;EPH receptor B6,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0048013//ephrin receptor signaling pathway;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0005003//ephrin receptor activity;GO:0004872//receptor activity,K05114//Axon guidance
205147,0,0,0,0,0,15,0,0,27,0,0,0,AMER3;APC membrane recruitment protein 3,GO:0005886//plasma membrane,GO:0016055//Wnt signaling pathway,GO:0005515//protein binding;GO:0008289//lipid binding,K06264//ECM-receptor interaction
2052,93,33,16,41,33,0,22,61,32,7,17,0,"EPHX1;epoxide hydrolase 1, microsomal (xenobiotic)",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0019439//aromatic compound catabolic process;GO:0009636//response to toxic substance,GO:0004301//epoxide hydrolase activity;GO:0033961//cis-stilbene-oxide hydrolase activity,K01253//Bile secretion;Metabolism of xenobiotics by cytochrome P450
205251,0,0,0,0,0,0,45,0,15,0,0,0,LINC00116;long intergenic non-protein coding RNA 116,GO:0016021//integral component of membrane,-,-,-
2053,68,156,6,119,289,33,0,1,25,1,4,0,"EPHX2;epoxide hydrolase 2, cytoplasmic",GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0046272//stilbene catabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0009636//response to toxic substance;GO:0006805//xenobiotic metabolic process;GO:0016311//dephosphorylation;GO:0010628//positive regulation of gene expression;GO:0006954//inflammatory response;GO:0019373//epoxygenase P450 pathway;GO:0046839//phospholipid dephosphorylation;GO:0045909//positive regulation of vasodilation;GO:0090181//regulation of cholesterol metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0042632//cholesterol homeostasis;GO:0008217//regulation of blood pressure;GO:0017144//drug metabolic process,GO:0042577//lipid phosphatase activity;GO:0004301//epoxide hydrolase activity;GO:0005102//receptor binding;GO:0000287//magnesium ion binding;GO:0033885//10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity;GO:0016791//phosphatase activity;GO:0015643//toxic substance binding;GO:0042803//protein homodimerization activity,K08726//Peroxisome;Arachidonic acid metabolism;Metabolic pathways
205327,0,20,0,17,79,33,0,0,36,0,0,0,C2orf69;chromosome 2 open reading frame 69,GO:0005576//extracellular region,-,-,-
2054,0,0,0,6,0,0,28,0,31,0,0,0,STX2;syntaxin 2,GO:0043231//intracellular membrane-bounded organelle;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005911//cell-cell junction;GO:0031410//cytoplasmic vesicle,GO:0007165//signal transduction;GO:0030193//regulation of blood coagulation;GO:0007398//ectoderm development;GO:0006886//intracellular protein transport;GO:0030154//cell differentiation;GO:0009887//organ morphogenesis;GO:0007340//acrosome reaction;GO:0010468//regulation of gene expression,GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding,K08486//SNARE interactions in vesicular transport;Synaptic vesicle cycle
205428,0,0,0,0,0,24,0,6,43,340,0,0,C3orf58;chromosome 3 open reading frame 58,GO:0030126//COPI vesicle coat;GO:0000139//Golgi membrane;GO:0005615//extracellular space,GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0060038//cardiac muscle cell proliferation,-,-
2055,91,0,0,0,16,25,29,0,48,0,0,331,"CLN8;ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)",GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane,GO:0008203//cholesterol metabolic process;GO:0051348//negative regulation of transferase activity;GO:0043066//negative regulation of apoptotic process;GO:0008306//associative learning;GO:0007628//adult walking behavior;GO:0050885//neuromuscular process controlling balance;GO:0044257//cellular protein catabolic process;GO:0045494//photoreceptor cell maintenance;GO:0007040//lysosome organization;GO:0050881//musculoskeletal movement;GO:0050884//neuromuscular process controlling posture;GO:0007006//mitochondrial membrane organization;GO:0006672//ceramide metabolic process;GO:0001306//age-dependent response to oxidative stress;GO:0045861//negative regulation of proteolysis;GO:0008219//cell death;GO:0008610//lipid biosynthetic process;GO:0008361//regulation of cell size;GO:0007399//nervous system development;GO:0006869//lipid transport;GO:0051935//L-glutamate uptake involved in synaptic transmission;GO:0046513//ceramide biosynthetic process;GO:0035176//social behavior;GO:0007601//visual perception;GO:0060052//neurofilament cytoskeleton organization;GO:0030163//protein catabolic process;GO:0021523//somatic motor neuron differentiation;GO:0006644//phospholipid metabolic process;GO:0060041//retina development in camera-type eye,-,-
205564,11,0,1,46,161,0,24,0,37,0,0,0,SENP5;SUMO1/sentrin specific peptidase 5,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0051301//cell division;GO:0016925//protein sumoylation;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0007049//cell cycle;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity,-
2056,0,0,0,0,0,21,0,0,19,0,0,0,EPO;erythropoietin,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface,"GO:0048678//response to axon injury;GO:0043627//response to estrogen;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0006915//apoptotic process;GO:0045740//positive regulation of DNA replication;GO:0045860//positive regulation of protein kinase activity;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0033189//response to vitamin A;GO:2001258//negative regulation of cation channel activity;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0008015//blood circulation;GO:1902251//negative regulation of erythrocyte apoptotic process;GO:0071474//cellular hyperosmotic response;GO:0045666//positive regulation of neuron differentiation;GO:0042541//hemoglobin biosynthetic process;GO:0070555//response to interleukin-1;GO:0007568//aging;GO:0009651//response to salt stress;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0007566//embryo implantation;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0051602//response to electrical stimulus;GO:0033574//response to testosterone;GO:0032496//response to lipopolysaccharide;GO:0071456//cellular response to hypoxia;GO:0055093//response to hyperoxia;GO:0043249//erythrocyte maturation;GO:0008284//positive regulation of cell proliferation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005128//erythropoietin receptor binding;GO:0005179//hormone activity;GO:0005515//protein binding;GO:0030295//protein kinase activator activity,K05437//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway
2057,0,55,56,17,28,0,0,0,23,0,11,0,EPOR;erythropoietin receptor,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0038162//erythropoietin-mediated signaling pathway;GO:0007420//brain development;GO:0007507//heart development;GO:0046697//decidualization;GO:0007165//signal transduction,GO:0004900//erythropoietin receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding,K05079//Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
205717,0,0,0,36,132,44,14,59,65,0,12,0,KIAA2018;KIAA2018,GO:0016020//membrane;GO:0005634//nucleus,GO:0008152//metabolic process,"GO:0003677//DNA binding;GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0046983//protein dimerization activity",K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
2058,0,44,1,33,154,2,45,0,12,0,0,220,EPRS;glutamyl-prolyl-tRNA synthetase,GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0097452//GAIT complex,GO:0006461//protein complex assembly;GO:0017148//negative regulation of translation;GO:0006433//prolyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0006424//glutamyl-tRNA aminoacylation;GO:0071346//cellular response to interferon-gamma;GO:0010467//gene expression,GO:0005524//ATP binding;GO:0004818//glutamate-tRNA ligase activity;GO:0004827//proline-tRNA ligase activity;GO:0035613//RNA stem-loop binding;GO:0005515//protein binding,K14163//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Porphyrin and chlorophyll metabolism;Biosynthesis of secondary metabolites
205860,0,0,0,0,0,13,0,26,0,0,3,0,TRIML2;tripartite motif family-like 2,-,GO:0016567//protein ubiquitination;GO:0032526//response to retinoic acid,GO:0016874//ligase activity,-
2059,0,1,0,18,35,14,84,0,41,0,17,0,EPS8;epidermal growth factor receptor pathway substrate 8,GO:0032420//stereocilium;GO:0032587//ruffle membrane;GO:0014069//postsynaptic density;GO:0031982//vesicle;GO:0005938//cell cortex;GO:0030426//growth cone;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex,GO:0051016//barbed-end actin filament capping;GO:0048149//behavioral response to ethanol;GO:0051764//actin crosslink formation;GO:0008283//cell proliferation;GO:0010458//exit from mitosis;GO:0031532//actin cytoskeleton reorganization;GO:0008360//regulation of cell shape;GO:0036336//dendritic cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008344//adult locomotory behavior;GO:0007165//signal transduction;GO:0051017//actin filament bundle assembly;GO:0016601//Rac protein signal transduction;GO:0070358//actin polymerization-dependent cell motility;GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0048365//Rac GTPase binding;GO:0003779//actin binding;GO:0005515//protein binding,K07365//T cell receptor signaling pathway;Axon guidance;Pathogenic Escherichia coli infection;ErbB signaling pathway
2060,76,119,2,165,305,55,0,0,73,0,0,0,EPS15;epidermal growth factor receptor pathway substrate 15,GO:0030122//AP-2 adaptor complex;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0005905//coated pit;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0008283//cell proliferation;GO:0006897//endocytosis;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0016050//vesicle organization;GO:0048268//clathrin coat assembly;GO:0015031//protein transport;GO:0006895//Golgi to endosome transport;GO:0032456//endocytic recycling;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0017124//SH3 domain binding;GO:0005509//calcium ion binding;GO:0031593//polyubiquitin binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K12472//Endocytosis
2063,0,0,0,0,1,0,0,0,0,0,0,0,"NR2F6;nuclear receptor subfamily 2, group F, member 6",GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0048666//neuron development;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043153//entrainment of circadian clock by photoperiod;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0050965//detection of temperature stimulus involved in sensory perception of pain,GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0004887//thyroid hormone receptor activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity,-
206338,0,0,0,0,1,20,24,0,50,0,12,0,AQPEP;laeverin,GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
206358,0,1,0,10,47,14,0,0,42,277,0,0,"SLC36A1;solute carrier family 36 (proton/amino acid symporter), member 1",GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,GO:0015808//L-alanine transport;GO:0055085//transmembrane transport;GO:0015816//glycine transport;GO:0006865//amino acid transport;GO:1902600//hydrogen ion transmembrane transport;GO:0035524//proline transmembrane transport;GO:0006811//ion transport,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015187//glycine transmembrane transporter activity;GO:0015193//L-proline transmembrane transporter activity;GO:0015293//symporter activity;GO:0015180//L-alanine transmembrane transporter activity,K14209//Protein digestion and absorption
2064,96,0,1,0,0,5,27,2,16,0,14,0,ERBB2;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2,GO:0016323//basolateral plasma membrane;GO:0043235//receptor complex;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0043406//positive regulation of MAP kinase activity;GO:0007528//neuromuscular junction development;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0042060//wound healing;GO:0007422//peripheral nervous system development;GO:0007411//axon guidance;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032886//regulation of microtubule-based process;GO:0045727//positive regulation of translation;GO:0045765//regulation of angiogenesis;GO:0007165//signal transduction;GO:0045785//positive regulation of cell adhesion;GO:0046777//protein autophosphorylation;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0006468//protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045087//innate immune response;GO:0007507//heart development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0008045//motor neuron axon guidance;GO:0006351//transcription, DNA-templated;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048709//oligodendrocyte differentiation;GO:0032321//positive regulation of Rho GTPase activity;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0023014//signal transduction by phosphorylation;GO:0007166//cell surface receptor signaling pathway;GO:0042552//myelination;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway",GO:0046982//protein heterodimerization activity;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0005515//protein binding;GO:0019838//growth factor binding;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0001042//RNA polymerase I core binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0043125//ErbB-3 class receptor binding;GO:0046983//protein dimerization activity;GO:0019903//protein phosphatase binding;GO:0005524//ATP binding,K05083//Pathways in cancer;Pancreatic cancer;Prostate cancer;Calcium signaling pathway;Endometrial cancer;Non-small cell lung cancer;Adherens junction;Bladder cancer;ErbB signaling pathway;Focal adhesion
206412,0,0,0,0,0,0,5,0,36,0,0,0,C6orf163;chromosome 6 open reading frame 163,-,-,-,-
206426,0,0,0,0,0,30,1,3,40,0,0,0,"PIP5K1P1;phosphatidylinositol-4-phosphate 5-kinase, type I, pseudogene 1",-,-,-,K00889//Phosphatidylinositol signaling system;Endocytosis;Metabolic pathways;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Inositol phosphate metabolism;Focal adhesion
2065,99,2,0,15,4,0,25,1,107,0,9,0,ERBB3;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3,GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016328//lateral plasma membrane;GO:0043235//receptor complex,GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0021545//cranial nerve development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007507//heart development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0051402//neuron apoptotic process;GO:0007422//peripheral nervous system development;GO:0042060//wound healing;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0048015//phosphatidylinositol-mediated signaling;GO:0003197//endocardial cushion development;GO:0043524//negative regulation of neuron apoptotic process;GO:0042127//regulation of cell proliferation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0014037//Schwann cell differentiation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0007162//negative regulation of cell adhesion;GO:0051048//negative regulation of secretion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0009968//negative regulation of signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0030296//protein tyrosine kinase activator activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004713//protein tyrosine kinase activity;GO:0019838//growth factor binding,K05084//Endocytosis;ErbB signaling pathway;Calcium signaling pathway
2066,109,0,0,0,0,36,40,0,81,421,0,0,ERBB4;v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4,GO:0005634//nucleus;GO:0043235//receptor complex;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,"GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0021551//central nervous system morphogenesis;GO:0007507//heart development;GO:0060644//mammary gland epithelial cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0060749//mammary gland alveolus development;GO:0008283//cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007595//lactation;GO:0016477//cell migration;GO:0023014//signal transduction by phosphorylation;GO:0030334//regulation of cell migration;GO:0001755//neural crest cell migration;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045165//cell fate commitment;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:2000366//positive regulation of STAT protein import into nucleus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021889//olfactory bulb interneuron differentiation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0009880//embryonic pattern specification;GO:0007165//signal transduction;GO:0046777//protein autophosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0061026//cardiac muscle tissue regeneration;GO:0007399//nervous system development;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway",GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0042803//protein homodimerization activity;GO:0005154//epidermal growth factor receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0044212//transcription regulatory region DNA binding,K05085//Calcium signaling pathway;ErbB signaling pathway;Endocytosis
2067,0,159,27,99,130,0,0,71,79,0,190,491,ERCC1;excision repair cross-complementation group 1,"GO:0005737//cytoplasm;GO:0000109//nucleotide-excision repair complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex;GO:0000784//nuclear chromosome, telomeric region","GO:0010259//multicellular organismal aging;GO:0006281//DNA repair;GO:0001302//replicative cell aging;GO:0006310//DNA recombination;GO:0006302//double-strand break repair;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0051276//chromosome organization;GO:0035166//post-embryonic hemopoiesis;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair;GO:0007584//response to nutrient;GO:0010165//response to X-ray;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006979//response to oxidative stress;GO:0006949//syncytium formation;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion;GO:0009744//response to sucrose;GO:0009650//UV protection;GO:0045190//isotype switching;GO:0008283//cell proliferation;GO:0035264//multicellular organism growth;GO:0032205//negative regulation of telomere maintenance;GO:0006312//mitotic recombination;GO:0036297//interstrand cross-link repair;GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0048568//embryonic organ development;GO:0048477//oogenesis",GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0017025//TBP-class protein binding;GO:0043566//structure-specific DNA binding;GO:0003684//damaged DNA binding;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0003697//single-stranded DNA binding;GO:0001094//TFIID-class transcription factor binding;GO:0019904//protein domain specific binding,K10849//Nucleotide excision repair;Fanconi anemia pathway
2068,0,0,1,15,0,0,28,242,19,29,0,0,ERCC2;excision repair cross-complementation group 2,GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0071817//MMXD complex;GO:0005737//cytoplasm;GO:0005675//holo TFIIH complex;GO:0005634//nucleus,"GO:0006281//DNA repair;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0044281//small molecule metabolic process;GO:0006360//transcription from RNA polymerase I promoter;GO:0035315//hair cell differentiation;GO:0043249//erythrocyte maturation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0009650//UV protection;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0030198//extracellular matrix organization;GO:0032289//central nervous system myelin formation;GO:0035264//multicellular organism growth;GO:0060218//hematopoietic stem cell differentiation;GO:0006370//7-methylguanosine mRNA capping;GO:0009791//post-embryonic development;GO:0033683//nucleotide-excision repair, DNA incision;GO:0050434//positive regulation of viral transcription;GO:0006200//ATP catabolic process;GO:0007568//aging;GO:0016032//viral process;GO:0030282//bone mineralization;GO:0006979//response to oxidative stress;GO:0007059//chromosome segregation;GO:0006289//nucleotide-excision repair;GO:0048820//hair follicle maturation;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0021510//spinal cord development;GO:0040016//embryonic cleavage;GO:0010467//gene expression;GO:0032508//DNA duplex unwinding;GO:0008283//cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043388//positive regulation of DNA binding","GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008094//DNA-dependent ATPase activity;GO:0008022//protein C-terminus binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0003677//DNA binding;GO:0043139//5'-3' DNA helicase activity;GO:0004672//protein kinase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0047485//protein N-terminus binding",K10844//Nucleotide excision repair;Basal transcription factors
2069,0,0,0,0,0,0,46,0,16,0,0,0,EREG;epiregulin,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042700//luteinizing hormone signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042327//positive regulation of phosphorylation;GO:0009653//anatomical structure morphogenesis;GO:0043616//keratinocyte proliferation;GO:0042060//wound healing;GO:0001819//positive regulation of cytokine production;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0009299//mRNA transcription;GO:0045860//positive regulation of protein kinase activity;GO:0045740//positive regulation of DNA replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030216//keratinocyte differentiation;GO:0030728//ovulation;GO:0019221//cytokine-mediated signaling pathway;GO:0043434//response to peptide hormone;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045087//innate immune response;GO:0001550//ovarian cumulus expansion;GO:0008284//positive regulation of cell proliferation;GO:0048160//primary follicle stage;GO:0001525//angiogenesis;GO:0045089//positive regulation of innate immune response;GO:0001556//oocyte maturation;GO:0008285//negative regulation of cell proliferation;GO:0007143//female meiotic division;GO:0048015//phosphatidylinositol-mediated signaling;GO:0009887//organ morphogenesis;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051781//positive regulation of cell division;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045840//positive regulation of mitosis",GO:0005154//epidermal growth factor receptor binding;GO:0008083//growth factor activity;GO:0005515//protein binding,K09784//ErbB signaling pathway
207,0,146,3,49,95,0,0,3,27,13,0,0,AKT1;v-akt murine thymoma viral oncogene homolog 1,GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005739//mitochondrion;GO:0005829//cytosol,"GO:0042593//glucose homeostasis;GO:0097194//execution phase of apoptosis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006924//activation-induced cell death of T cells;GO:0032287//peripheral nervous system myelin maintenance;GO:0006809//nitric oxide biosynthetic process;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0048015//phosphatidylinositol-mediated signaling;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0042640//anagen;GO:0046209//nitric oxide metabolic process;GO:0006417//regulation of translation;GO:0035556//intracellular signal transduction;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0031018//endocrine pancreas development;GO:0008637//apoptotic mitochondrial changes;GO:0060709//glycogen cell differentiation involved in embryonic placenta development;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0016070//RNA metabolic process;GO:0030168//platelet activation;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0030334//regulation of cell migration;GO:0010975//regulation of neuron projection development;GO:0010951//negative regulation of endopeptidase activity;GO:0008286//insulin receptor signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0006464//cellular protein modification process;GO:0031295//T cell costimulation;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0005978//glycogen biosynthetic process;GO:0010907//positive regulation of glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0070141//response to UV-A;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0015758//glucose transport;GO:0034405//response to fluid shear stress;GO:0032094//response to food;GO:0009408//response to heat;GO:0001938//positive regulation of endothelial cell proliferation;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0097193//intrinsic apoptotic signaling pathway;GO:0030154//cell differentiation;GO:0000060//protein import into nucleus, translocation;GO:0016071//mRNA metabolic process;GO:0018105//peptidyl-serine phosphorylation;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0005979//regulation of glycogen biosynthetic process;GO:0010507//negative regulation of autophagy;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0071260//cellular response to mechanical stimulus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0046329//negative regulation of JNK cascade;GO:0045087//innate immune response;GO:0043491//protein kinase B signaling;GO:0010765//positive regulation of sodium ion transport;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0032270//positive regulation of cellular protein metabolic process;GO:0060644//mammary gland epithelial cell differentiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0032869//cellular response to insulin stimulus;GO:0060716//labyrinthine layer blood vessel development;GO:1901976//regulation of cell cycle checkpoint;GO:0001893//maternal placenta development;GO:0007568//aging;GO:0001649//osteoblast differentiation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0030163//protein catabolic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007596//blood coagulation;GO:0050999//regulation of nitric-oxide synthase activity;GO:0001934//positive regulation of protein phosphorylation;GO:0051146//striated muscle cell differentiation;GO:0007281//germ cell development;GO:0045861//negative regulation of proteolysis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006412//translation;GO:0016567//protein ubiquitination;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0016310//phosphorylation;GO:0030212//hyaluronan metabolic process;GO:0006006//glucose metabolic process;GO:0046777//protein autophosphorylation;GO:0045792//negative regulation of cell size;GO:0007165//signal transduction;GO:0030030//cell projection organization;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0046889//positive regulation of lipid biosynthetic process;GO:0006915//apoptotic process;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0006468//protein phosphorylation;GO:0061024//membrane organization","GO:0071889//14-3-3 protein binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0019899//enzyme binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005080//protein kinase C binding",K04456//Jak-STAT signaling pathway;HTLV-I infection;Fc gamma R-mediated phagocytosis;Toxoplasmosis;Osteoclast differentiation;Endometrial cancer;VEGF signaling pathway;Focal adhesion;Glioma;Pancreatic cancer;Pathways in cancer;Chemokine signaling pathway;Dopaminergic synapse;Influenza A;Toll-like receptor signaling pathway;mTOR signaling pathway;Apoptosis;MAPK signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;ErbB signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Tight junction;B cell receptor signaling pathway;Hepatitis C;Melanoma;Neurotrophin signaling pathway;Adipocytokine signaling pathway;Non-small cell lung cancer;Measles;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;Prostate cancer;Tuberculosis;Chronic myeloid leukemia;T cell receptor signaling pathway;Colorectal cancer
207063,0,0,0,10,18,4,0,0,42,0,0,0,DHRSX;dehydrogenase/reductase (SDR family) X-linked,-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
2071,0,0,0,19,16,10,0,0,34,0,5,0,ERCC3;excision repair cross-complementation group 3,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005675//holo TFIIH complex;GO:0005730//nucleolus,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0035315//hair cell differentiation;GO:0006360//transcription from RNA polymerase I promoter;GO:0009650//UV protection;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0009411//response to UV;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000717//nucleotide-excision repair, DNA duplex unwinding;GO:0008104//protein localization;GO:0010467//gene expression;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0050434//positive regulation of viral transcription;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006200//ATP catabolic process;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0043065//positive regulation of apoptotic process;GO:0006265//DNA topological change;GO:0006979//response to oxidative stress;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006468//protein phosphorylation",GO:0008094//DNA-dependent ATPase activity;GO:0042277//peptide binding;GO:0016887//ATPase activity;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0043138//3'-5' DNA helicase activity;GO:0008022//protein C-terminus binding;GO:0003684//damaged DNA binding;GO:0032564//dATP binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0047485//protein N-terminus binding,K10843//Nucleotide excision repair;Basal transcription factors
207147,0,0,0,0,0,30,1,0,12,0,0,0,TRY2P;trypsinogen-like pseudogene,-,-,-,K01312//Protein digestion and absorption;Influenza A;Neuroactive ligand-receptor interaction;Pancreatic secretion
2072,0,1,0,14,47,0,78,0,36,0,4,0,ERCC4;excision repair cross-complementation group 4,"GO:0000110//nucleotide-excision repair factor 1 complex;GO:0000784//nuclear chromosome, telomeric region;GO:0005669//transcription factor TFIID complex;GO:0000109//nucleotide-excision repair complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region","GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000724//double-strand break repair via homologous recombination;GO:1901255//nucleotide-excision repair involved in interstrand cross-link repair;GO:0010834//telomere maintenance via telomere shortening;GO:0033683//nucleotide-excision repair, DNA incision;GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0006281//DNA repair;GO:0009411//response to UV;GO:0000723//telomere maintenance;GO:0000712//resolution of meiotic recombination intermediates;GO:0032205//negative regulation of telomere maintenance;GO:0009650//UV protection;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion",GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0001094//TFIID-class transcription factor binding;GO:0003697//single-stranded DNA binding;GO:0004520//endodeoxyribonuclease activity;GO:0047485//protein N-terminus binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0003684//damaged DNA binding;GO:0043566//structure-specific DNA binding,K10848//Nucleotide excision repair;Fanconi anemia pathway
2073,0,0,23,0,17,0,6,0,1,0,64,0,ERCC5;excision repair cross-complementation group 5,"GO:0005662//DNA replication factor A complex;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0006295//nucleotide-excision repair, DNA incision, 3'-to lesion;GO:0006281//DNA repair;GO:0009650//UV protection;GO:0043066//negative regulation of apoptotic process;GO:0010225//response to UV-C;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0009411//response to UV;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006289//nucleotide-excision repair;GO:0000737//DNA catabolic process, endonucleolytic",GO:0003697//single-stranded DNA binding;GO:0004520//endodeoxyribonuclease activity;GO:0047485//protein N-terminus binding;GO:0042803//protein homodimerization activity;GO:0000405//bubble DNA binding;GO:0004519//endonuclease activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding,K10846//Nucleotide excision repair
2074,0,0,22,18,85,9,0,0,45,0,0,0,ERCC6;excision repair cross-complementation group 6,GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0032784//regulation of DNA-templated transcription, elongation;GO:0035264//multicellular organism growth;GO:0009411//response to UV;GO:0010224//response to UV-B;GO:0045494//photoreceptor cell maintenance;GO:0010332//response to gamma radiation;GO:0007256//activation of JNKK activity;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0009636//response to toxic substance;GO:0007257//activation of JUN kinase activity;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0010165//response to X-ray;GO:0006290//pyrimidine dimer repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006979//response to oxidative stress;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0006284//base-excision repair;GO:0006281//DNA repair;GO:0000303//response to superoxide;GO:0006200//ATP catabolic process;GO:0032786//positive regulation of DNA-templated transcription, elongation",GO:0008022//protein C-terminus binding;GO:0008094//DNA-dependent ATPase activity;GO:0005515//protein binding;GO:0030296//protein tyrosine kinase activator activity;GO:0047485//protein N-terminus binding;GO:0032403//protein complex binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0003677//DNA binding,K10841//Nucleotide excision repair
2078,1,0,0,0,14,1,0,1,33,0,5,0,ERG;v-ets avian erythroblastosis virus E26 oncogene homolog,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex,GO:0006468//protein phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0007165//signal transduction;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0003677//DNA binding,K09435//Transcriptional misregulation in cancer
2079,0,40,0,22,93,0,0,0,4,0,0,0,ERH;enhancer of rudimentary homolog (Drosophila),GO:0030496//midbody;GO:0016020//membrane,GO:0006139//nucleobase-containing compound metabolic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0001649//osteoblast differentiation;GO:0007049//cell cycle,GO:0044822//poly(A) RNA binding,-
208,0,1,0,1,7,33,0,1,7,0,0,301,AKT2;v-akt murine thymoma viral oncogene homolog 2,GO:0005938//cell cortex;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0032587//ruffle membrane,GO:0032859//activation of Ral GTPase activity;GO:0032869//cellular response to insulin stimulus;GO:0072659//protein localization to plasma membrane;GO:0046326//positive regulation of glucose import;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0006417//regulation of translation;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0008643//carbohydrate transport;GO:0006464//cellular protein modification process;GO:0090314//positive regulation of protein targeting to membrane;GO:0031340//positive regulation of vesicle fusion;GO:0060644//mammary gland epithelial cell differentiation;GO:2000147//positive regulation of cell motility;GO:0010907//positive regulation of glucose metabolic process;GO:0005978//glycogen biosynthetic process;GO:0032287//peripheral nervous system myelin maintenance;GO:0006915//apoptotic process;GO:0065002//intracellular protein transmembrane transport;GO:0071156//regulation of cell cycle arrest;GO:0008286//insulin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0061024//membrane organization;GO:0006468//protein phosphorylation;GO:0045444//fat cell differentiation;GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0030334//regulation of cell migration;GO:0032000//positive regulation of fatty acid beta-oxidation,GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K04456//Chagas disease (American trypanosomiasis);Tight junction;Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;B cell receptor signaling pathway;Non-small cell lung cancer;Adipocytokine signaling pathway;Neurotrophin signaling pathway;Melanoma;Hepatitis C;Measles;Insulin signaling pathway;Tuberculosis;Prostate cancer;Carbohydrate digestion and absorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;T cell receptor signaling pathway;Chronic myeloid leukemia;Colorectal cancer;HTLV-I infection;Jak-STAT signaling pathway;Fc gamma R-mediated phagocytosis;Endometrial cancer;Toxoplasmosis;Osteoclast differentiation;Glioma;Focal adhesion;VEGF signaling pathway;Dopaminergic synapse;Pathways in cancer;Chemokine signaling pathway;Pancreatic cancer;Toll-like receptor signaling pathway;Influenza A;MAPK signaling pathway;Apoptosis;mTOR signaling pathway;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection
2081,0,0,0,0,0,0,9,8,58,0,0,0,ERN1;endoplasmic reticulum to nucleus signaling 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005637//nuclear inner membrane;GO:0005739//mitochondrion,"GO:0046777//protein autophosphorylation;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:0006355//regulation of transcription, DNA-templated;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007050//cell cycle arrest;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0044267//cellular protein metabolic process;GO:0006468//protein phosphorylation;GO:0070055//HAC1-type intron splice site recognition and cleavage;GO:0006351//transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0019899//enzyme binding;GO:0000287//magnesium ion binding;GO:0004521//endoribonuclease activity;GO:0005524//ATP binding,K08852//Protein processing in endoplasmic reticulum;Alzheimer's disease
2086,0,15,0,0,0,2,16,0,26,0,0,0,"ERV3-1;endogenous retrovirus group 3, member 1",GO:0070062//extracellular vesicular exosome;GO:0019031//viral envelope,-,-,-
2091,0,34,47,11,42,0,0,50,1,0,0,0,FBL;fibrillarin,GO:0016020//membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0015030//Cajal body;GO:0001652//granular component;GO:0031428//box C/D snoRNP complex;GO:0005634//nucleus,GO:0008033//tRNA processing;GO:0016074//snoRNA metabolic process;GO:1990258//histone glutamine methylation;GO:0001649//osteoblast differentiation;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:1990259//histone-glutamine methyltransferase activity;GO:0003723//RNA binding,K14563//Ribosome biogenesis in eukaryotes
2098,31,28,0,1,21,31,0,65,0,1,5,0,ESD;esterase D,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0046294//formaldehyde catabolic process,"GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0018738//S-formylglutathione hydrolase activity",K01070//Two-component system;Microbial metabolism in diverse environments;Methane metabolism
2099,0,0,0,0,0,31,16,85,33,0,3,75,ESR1;estrogen receptor 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0035327//transcriptionally active chromatin;GO:0016020//membrane,"GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010629//negative regulation of gene expression;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0010467//gene expression;GO:0048146//positive regulation of fibroblast proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0060749//mammary gland alveolus development;GO:0032355//response to estradiol;GO:0010863//positive regulation of phospholipase C activity;GO:0002064//epithelial cell development;GO:0060745//mammary gland branching involved in pregnancy;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0008209//androgen metabolic process;GO:0008584//male gonad development;GO:0006338//chromatin remodeling;GO:0043401//steroid hormone mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001547//antral ovarian follicle growth;GO:0006355//regulation of transcription, DNA-templated;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0060065//uterus development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0060523//prostate epithelial cord elongation;GO:0060068//vagina development;GO:0071392//cellular response to estradiol stimulus;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0007165//signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042981//regulation of apoptotic process;GO:0043627//response to estrogen;GO:0051000//positive regulation of nitric-oxide synthase activity",GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0038052//estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005496//steroid binding;GO:0030284//estrogen receptor activity;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0003707//steroid hormone receptor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001046//core promoter sequence-specific DNA binding;GO:0034056//estrogen response element binding;GO:0008013//beta-catenin binding;GO:0030235//nitric-oxide synthase regulator activity,K08550//Endocrine and other factor-regulated calcium reabsorption
21,0,0,0,9,23,26,4,125,10,0,15,314,"ABCA3;ATP-binding cassette, sub-family A (ABC1), member 3",GO:0097208//alveolar lamellar body;GO:0005886//plasma membrane;GO:0097233//alveolar lamellar body membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0006200//ATP catabolic process;GO:0055085//transmembrane transport;GO:0006810//transport;GO:0042493//response to drug,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005215//transporter activity;GO:0005524//ATP binding",K05643//ABC transporters
210,0,0,0,21,83,0,0,50,25,16,0,0,ALAD;aminolevulinate dehydratase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006783//heme biosynthetic process;GO:0051260//protein homooligomerization;GO:0071353//cellular response to interleukin-4;GO:0006778//porphyrin-containing compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process,GO:0003824//catalytic activity;GO:0032791//lead ion binding;GO:0042802//identical protein binding;GO:0004655//porphobilinogen synthase activity;GO:0008270//zinc ion binding,K01698//Biosynthesis of secondary metabolites;Porphyrin and chlorophyll metabolism;Metabolic pathways
2100,4,0,0,0,0,6,1,4,30,0,20,0,ESR2;estrogen receptor 2 (ER beta),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005576//extracellular region,"GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0060068//vagina development;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0060065//uterus development;GO:1900116//extracellular negative regulation of signal transduction;GO:0007267//cell-cell signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030308//negative regulation of cell growth;GO:0007420//brain development;GO:0010467//gene expression;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050680//negative regulation of epithelial cell proliferation;GO:0007165//signal transduction;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0001541//ovarian follicle development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001764//neuron migration;GO:0043401//steroid hormone mediated signaling pathway;GO:0060740//prostate gland epithelium morphogenesis",GO:0003713//transcription coactivator activity;GO:0019899//enzyme binding;GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0030284//estrogen receptor activity;GO:0034056//estrogen response element binding;GO:0048019//receptor antagonist activity;GO:0005496//steroid binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2101,0,9,128,128,184,0,0,42,0,0,82,0,ESRRA;estrogen-related receptor alpha,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus,"GO:0030522//intracellular receptor signaling pathway;GO:0042127//regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045670//regulation of osteoclast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0051216//cartilage development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045667//regulation of osteoblast differentiation;GO:0010467//gene expression",GO:0005496//steroid binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005515//protein binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0019904//protein domain specific binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,-
2103,0,0,0,0,0,0,15,0,14,0,2,0,ESRRB;estrogen-related receptor beta,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001831//trophectodermal cellular morphogenesis;GO:0030522//intracellular receptor signaling pathway;GO:0001892//embryonic placenta development;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0001834//trophectodermal cell proliferation;GO:0010467//gene expression;GO:0019827//stem cell maintenance",GO:0005496//steroid binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding,-
2104,0,1,0,3,3,0,19,0,24,91,0,54,ESRRG;estrogen-related receptor gamma,GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0048384//retinoic acid receptor signaling pathway;GO:0043401//steroid hormone mediated signaling pathway",GO:0050682//AF-2 domain binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003708//retinoic acid receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0005496//steroid binding,-
2107,0,43,1,73,153,14,21,65,58,139,23,0,ETF1;eukaryotic translation termination factor 1,GO:0005829//cytosol;GO:0005737//cytoplasm,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006479//protein methylation;GO:0006412//translation;GO:0006449//regulation of translational termination;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0043022//ribosome binding;GO:0003723//RNA binding;GO:0003747//translation release factor activity;GO:0016149//translation release factor activity, codon specific;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding",K03265//mRNA surveillance pathway
2108,103,0,1,3,25,0,5,0,45,0,0,315,"ETFA;electron-transfer-flavoprotein, alpha polypeptide",GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain,GO:0016491//oxidoreductase activity;GO:0009055//electron carrier activity;GO:0050660//flavin adenine dinucleotide binding,K03522//Nitrogen metabolism;Sulfur relay system
2109,0,28,1,8,3,11,0,65,30,0,0,0,"ETFB;electron-transfer-flavoprotein, beta polypeptide",GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle,GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain,GO:0009055//electron carrier activity,K03521//Nitrogen metabolism
211,9,1,1,16,43,0,0,0,16,0,0,0,"ALAS1;aminolevulinate, delta-, synthase 1",GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006778//porphyrin-containing compound metabolic process;GO:0006783//heme biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process,GO:0003870//5-aminolevulinate synthase activity;GO:0030170//pyridoxal phosphate binding,"K00643//Glycine, serine and threonine metabolism;Metabolic pathways;Porphyrin and chlorophyll metabolism"
2110,0,0,1,5,51,0,0,0,0,0,39,0,ETFDH;electron-transferring-flavoprotein dehydrogenase,GO:0031966//mitochondrial membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0022900//electron transport chain,"GO:0043783//oxidoreductase activity, oxidizing metal ions with flavin as acceptor;GO:0004174//electron-transferring-flavoprotein dehydrogenase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0048038//quinone binding;GO:0009055//electron carrier activity;GO:0016491//oxidoreductase activity;GO:0046872//metal ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0048039//ubiquinone binding",-
2113,0,0,0,7,12,15,9,47,15,0,1,0,ETS1;v-ets avian erythroblastosis virus E26 oncogene homolog 1,GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0032355//response to estradiol;GO:0010715//regulation of extracellular matrix disassembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045786//negative regulation of cell cycle;GO:0045765//regulation of angiogenesis;GO:0060206//estrous cycle phase;GO:0042981//regulation of apoptotic process;GO:0070555//response to interleukin-1;GO:0048870//cell motility;GO:0001666//response to hypoxia;GO:0009612//response to mechanical stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0021983//pituitary gland development;GO:0046677//response to antibiotic;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060055//angiogenesis involved in wound healing;GO:0034616//response to laminar fluid shear stress;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:0021854//hypothalamus development;GO:0010595//positive regulation of endothelial cell migration;GO:0045648//positive regulation of erythrocyte differentiation;GO:0030578//PML body organization;GO:0006955//immune response;GO:0070301//cellular response to hydrogen peroxide",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0035035//histone acetyltransferase binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,K02678//HTLV-I infection;MAPK signaling pathway - fly;Pathways in cancer;Renal cell carcinoma;Dorso-ventral axis formation
2114,75,0,0,0,0,0,28,0,16,0,0,0,ETS2;v-ets avian erythroblastosis virus E26 oncogene homolog 2,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001501//skeletal system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0035259//glucocorticoid receptor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K02678//Renal cell carcinoma;Dorso-ventral axis formation;MAPK signaling pathway - fly;Pathways in cancer;HTLV-I infection
2115,0,0,0,0,0,19,0,147,60,1,0,0,ETV1;ets variant 1,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0007638//mechanosensory behavior;GO:0007411//axon guidance;GO:0006366//transcription from RNA polymerase II promoter;GO:0048935//peripheral nervous system neuron development,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K09431//Transcriptional misregulation in cancer
2116,75,0,0,0,0,0,0,0,0,0,0,0,ETV2;ets variant 2,GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0030218//erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048514//blood vessel morphogenesis;GO:0007219//Notch signaling pathway;GO:0016055//Wnt signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:2000382//positive regulation of mesoderm development;GO:0045603//positive regulation of endothelial cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0060803//BMP signaling pathway involved in mesodermal cell fate specification;GO:0001824//blastocyst development;GO:0001890//placenta development,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
2117,0,0,2,0,0,21,0,0,42,0,0,0,ETV3;ets variant 3,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
2118,0,39,0,0,0,0,0,0,71,0,10,0,ETV4;ets variant 4,GO:0005730//nucleolus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008045//motor neuron axon guidance;GO:0048863//stem cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K15592//Transcriptional misregulation in cancer
2119,55,0,0,0,0,13,0,0,12,0,0,287,ETV5;ets variant 5,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0060252//positive regulation of glial cell proliferation;GO:0050807//regulation of synapse organization;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0007626//locomotory behavior;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0007274//neuromuscular synaptic transmission;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034599//cellular response to oxidative stress;GO:0048133//male germ-line stem cell asymmetric division;GO:0045666//positive regulation of neuron differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K15593//Transcriptional misregulation in cancer
212,85,0,0,0,0,7,0,0,25,0,22,0,"ALAS2;aminolevulinate, delta-, synthase 2",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0032364//oxygen homeostasis;GO:0006783//heme biosynthetic process;GO:0001666//response to hypoxia;GO:0006778//porphyrin-containing compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006879//cellular iron ion homeostasis;GO:0042541//hemoglobin biosynthetic process;GO:0030218//erythrocyte differentiation,GO:0016594//glycine binding;GO:0030170//pyridoxal phosphate binding;GO:0050662//coenzyme binding;GO:0003870//5-aminolevulinate synthase activity;GO:0005515//protein binding,"K00643//Metabolic pathways;Porphyrin and chlorophyll metabolism;Glycine, serine and threonine metabolism"
2120,2,0,0,19,57,0,22,0,24,0,0,0,ETV6;ets variant 6,GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation,GO:0019904//protein domain specific binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,K03211//MAPK signaling pathway - fly;Transcriptional misregulation in cancer;Dorso-ventral axis formation
2121,0,0,0,0,0,11,0,153,62,2,9,0,EVC;Ellis van Creveld syndrome,GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0016021//integral component of membrane;GO:0036064//ciliary basal body;GO:0005929//cilium,GO:0051216//cartilage development;GO:0003416//endochondral bone growth;GO:0007517//muscle organ development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0001501//skeletal system development;GO:0007224//smoothened signaling pathway,-,K04574//Amyotrophic lateral sclerosis (ALS);K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
2122,0,28,0,0,10,27,14,100,67,0,11,0,MECOM;MDS1 and EVI1 complex locus,GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0016607//nuclear speck,"GO:0043069//negative regulation of programmed cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0071425//hematopoietic stem cell proliferation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0046329//negative regulation of JNK cascade;GO:0051726//regulation of cell cycle",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K04462//MAPK signaling pathway;Pathways in cancer;Chronic myeloid leukemia
2123,0,0,0,0,0,0,54,0,20,0,6,1,EVI2A;ecotropic viral integration site 2A,GO:0016021//integral component of membrane,GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity,-
2124,0,0,0,0,0,0,2,0,0,0,0,0,EVI2B;ecotropic viral integration site 2B,GO:0005887//integral component of plasma membrane,-,-,K10955//Vibrio cholerae infection;Amoebiasis
2125,0,0,0,0,6,27,0,40,18,0,0,0,EVPL;envoplakin,GO:0030057//desmosome;GO:0070062//extracellular vesicular exosome;GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0030216//keratinocyte differentiation;GO:0008544//epidermis development;GO:0018149//peptide cross-linking,"GO:0005198//structural molecule activity;GO:0030674//protein binding, bridging",-
2128,0,0,0,3,0,0,27,29,9,0,24,314,EVX1;even-skipped homeobox 1,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0009792//embryo development ending in birth or egg hatching,GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
213,0,0,0,0,0,14,0,0,44,0,0,0,ALB;albumin,GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0031093//platelet alpha granule lumen;GO:0005634//nucleus,"GO:0070541//response to platinum ion;GO:0042157//lipoprotein metabolic process;GO:0009267//cellular response to starvation;GO:0051659//maintenance of mitochondrion location;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:0030168//platelet activation;GO:0043252//sodium-independent organic anion transport;GO:0001895//retina homeostasis;GO:0007584//response to nutrient;GO:0006810//transport;GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0010033//response to organic substance;GO:0043069//negative regulation of programmed cell death;GO:0015721//bile acid and bile salt transport;GO:0044281//small molecule metabolic process;GO:0046689//response to mercury ion;GO:0043066//negative regulation of apoptotic process;GO:0019836//hemolysis by symbiont of host erythrocytes;GO:0008206//bile acid metabolic process;GO:0055085//transmembrane transport",GO:0019825//oxygen binding;GO:0030170//pyridoxal phosphate binding;GO:0005504//fatty acid binding;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0015643//toxic substance binding;GO:0005515//protein binding;GO:0051087//chaperone binding;GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0003677//DNA binding;GO:0016209//antioxidant activity,K01883//Aminoacyl-tRNA biosynthesis;Metabolic pathways;DNA replication;Ribosome;Arginine and proline metabolism
2130,0,34,0,1,43,32,3,0,45,34,22,0,EWSR1;EWS RNA-binding protein 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005516//calmodulin binding;GO:0003723//RNA binding;GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0042802//identical protein binding,K13209//Transcriptional misregulation in cancer
2131,0,0,0,0,0,24,120,0,10,0,0,0,EXT1;exostosin glycosyltransferase 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum,"GO:0044281//small molecule metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0072498//embryonic skeletal joint development;GO:0001503//ossification;GO:0007411//axon guidance;GO:0007492//endoderm development;GO:0007498//mesoderm development;GO:0030203//glycosaminoglycan metabolic process;GO:0007165//signal transduction;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0007369//gastrulation;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0021772//olfactory bulb development;GO:0001501//skeletal system development;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process","GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042803//protein homodimerization activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0046982//protein heterodimerization activity;GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups;GO:0015020//glucuronosyltransferase activity",K02366//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
2132,106,0,0,0,3,41,32,0,3,0,7,0,EXT2;exostosin glycosyltransferase 2,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0030203//glycosaminoglycan metabolic process;GO:0030154//cell differentiation;GO:0005975//carbohydrate metabolic process;GO:0001707//mesoderm formation;GO:0006486//protein glycosylation;GO:0001503//ossification;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process","GO:0050509//N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity;GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042328//heparan sulfate N-acetylglucosaminyltransferase activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0016757//transferase activity, transferring glycosyl groups",K02367//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
2134,0,0,0,0,0,0,0,1,40,0,1,0,EXTL1;exostosin-like glycosyltransferase 1,GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane,GO:0001501//skeletal system development;GO:0006486//protein glycosylation,GO:0050508//glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity,K02368//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
2135,0,1,0,11,0,8,1,0,47,0,22,0,EXTL2;exostosin-like glycosyltransferase 2,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome,GO:0006044//N-acetylglucosamine metabolic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,"GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding;GO:0035248//alpha-1,4-N-acetylgalactosaminyltransferase activity",K02369//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
2137,0,0,1,0,0,0,42,3,7,152,10,0,EXTL3;exostosin-like glycosyltransferase 3,GO:0005789//endoplasmic reticulum membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030307//positive regulation of cell growth,GO:0046872//metal ion binding;GO:0001888//glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity,K02370//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
2138,0,0,0,0,0,0,64,0,26,0,0,0,EYA1;EYA transcriptional coactivator and phosphatase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045747//positive regulation of Notch signaling pathway;GO:0034613//cellular protein localization;GO:0000132//establishment of mitotic spindle orientation;GO:0060487//lung epithelial cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006302//double-strand break repair;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071600//otic vesicle morphogenesis;GO:0007389//pattern specification process;GO:0045739//positive regulation of DNA repair;GO:0009653//anatomical structure morphogenesis;GO:0042473//outer ear morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0010212//response to ionizing radiation;GO:0001656//metanephros development;GO:0060037//pharyngeal system development;GO:0014706//striated muscle tissue development;GO:0007605//sensory perception of sound;GO:0048704//embryonic skeletal system morphogenesis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0016925//protein sumoylation;GO:0016576//histone dephosphorylation;GO:0090103//cochlea morphogenesis;GO:0035909//aorta morphogenesis;GO:0042474//middle ear morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0048665//neuron fate specification;GO:0045664//regulation of neuron differentiation",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0003723//RNA binding,K15616//Transcriptional misregulation in cancer
2139,0,22,0,3,38,0,0,0,46,0,0,0,EYA2;EYA transcriptional coactivator and phosphatase 2,GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm,"GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006351//transcription, DNA-templated;GO:0014706//striated muscle tissue development;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0007501//mesodermal cell fate specification;GO:0016576//histone dephosphorylation;GO:0097345//mitochondrial outer membrane permeabilization",GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity,-
214,0,9,0,0,2,0,0,70,9,0,0,0,ALCAM;activated leukocyte cell adhesion molecule,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0030424//axon;GO:0005925//focal adhesion;GO:0043025//neuronal cell body,GO:0008045//motor neuron axon guidance;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0007165//signal transduction,GO:0005102//receptor binding;GO:0005515//protein binding,K06547//Cell adhesion molecules (CAMs)
2140,0,38,0,1,17,37,46,0,76,0,0,0,EYA3;EYA transcriptional coactivator and phosphatase 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0010212//response to ionizing radiation;GO:0016576//histone dephosphorylation;GO:0006302//double-strand break repair;GO:0007601//visual perception;GO:0007275//multicellular organismal development;GO:0045739//positive regulation of DNA repair;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0003682//chromatin binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
2145,0,0,0,18,18,29,0,0,110,17,0,0,EZH1;enhancer of zeste 1 polycomb repressive complex 2 subunit,GO:0005730//nucleolus;GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070734//histone H3-K27 methylation;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis",GO:0003682//chromatin binding;GO:0046976//histone methyltransferase activity (H3-K27 specific),-
2146,0,17,0,0,0,20,0,0,10,0,0,0,EZH2;enhancer of zeste 2 polycomb repressive complex 2 subunit,GO:0000790//nuclear chromatin;GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0045120//pronucleus,"GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0043406//positive regulation of MAP kinase activity;GO:0070314//G1 to G0 transition;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0071168//protein localization to chromatin;GO:0070301//cellular response to hydrogen peroxide;GO:0006351//transcription, DNA-templated;GO:0045814//negative regulation of gene expression, epigenetic;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0070734//histone H3-K27 methylation;GO:0042127//regulation of cell proliferation;GO:0014013//regulation of gliogenesis;GO:0045605//negative regulation of epidermal cell differentiation;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0021695//cerebellar cortex development;GO:0006306//DNA methylation;GO:0042752//regulation of circadian rhythm;GO:0032320//positive regulation of Ras GTPase activity;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003723//RNA binding;GO:0046976//histone methyltransferase activity (H3-K27 specific);GO:0003682//chromatin binding;GO:0001047//core promoter binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042054//histone methyltransferase activity,-
2147,0,1,0,0,0,14,0,126,0,0,5,292,F2;coagulation factor II (thrombin),GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0072562//blood microparticle;GO:0005576//extracellular region,"GO:0051480//cytosolic calcium ion homeostasis;GO:0008360//regulation of cell shape;GO:0042730//fibrinolysis;GO:0032967//positive regulation of collagen biosynthetic process;GO:0030307//positive regulation of cell growth;GO:0006953//acute-phase response;GO:0007597//blood coagulation, intrinsic pathway;GO:0030193//regulation of blood coagulation;GO:0045861//negative regulation of proteolysis;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0010544//negative regulation of platelet activation;GO:0008284//positive regulation of cell proliferation;GO:0006508//proteolysis;GO:0007275//multicellular organismal development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0044267//cellular protein metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0009611//response to wounding;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0043687//post-translational protein modification;GO:0048712//negative regulation of astrocyte differentiation;GO:1900738//positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030194//positive regulation of blood coagulation",GO:0005102//receptor binding;GO:0070053//thrombospondin receptor activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K01313//Regulation of actin cytoskeleton;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
2149,0,0,0,0,0,0,19,0,54,0,0,0,F2R;coagulation factor II (thrombin) receptor,GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0031094//platelet dense tubular network;GO:0005886//plasma membrane;GO:0031594//neuromuscular junction;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0045211//postsynaptic membrane,"GO:0006954//inflammatory response;GO:0070493//thrombin receptor signaling pathway;GO:0007262//STAT protein import into nucleus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0051930//regulation of sensory perception of pain;GO:2000778//positive regulation of interleukin-6 secretion;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1900134//negative regulation of renin secretion into blood stream;GO:0045987//positive regulation of smooth muscle contraction;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030193//regulation of blood coagulation;GO:0003105//negative regulation of glomerular filtration;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:2000484//positive regulation of interleukin-8 secretion;GO:0009653//anatomical structure morphogenesis;GO:0048873//homeostasis of number of cells within a tissue;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0046427//positive regulation of JAK-STAT cascade;GO:0030194//positive regulation of blood coagulation;GO:0043524//negative regulation of neuron apoptotic process;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0030168//platelet activation;GO:0009611//response to wounding;GO:0007596//blood coagulation;GO:0032651//regulation of interleukin-1 beta production;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0007529//establishment of synaptic specificity at neuromuscular junction;GO:0045907//positive regulation of vasoconstriction;GO:0060155//platelet dense granule organization;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0008284//positive regulation of cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0051928//positive regulation of calcium ion transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0000186//activation of MAPKK activity;GO:0035025//positive regulation of Rho protein signal transduction;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0008285//negative regulation of cell proliferation",GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding;GO:0015057//thrombin receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005102//receptor binding;GO:0001965//G-protein alpha-subunit binding,K03914//Endocytosis;Regulation of actin cytoskeleton;Calcium signaling pathway;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
215,96,0,0,0,13,0,0,0,14,0,19,0,"ABCD1;ATP-binding cassette, sub-family D (ALD), member 1",GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005778//peroxisomal membrane,GO:0044255//cellular lipid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0042760//very long-chain fatty acid catabolic process;GO:0015910//peroxisomal long-chain fatty acid import;GO:0042758//long-chain fatty acid catabolic process;GO:0043651//linoleic acid metabolic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0015919//peroxisomal membrane transport,"GO:0005215//transporter activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005325//peroxisomal fatty-acyl-CoA transporter activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0016887//ATPase activity",K05675//ABC transporters;Peroxisome
2150,0,0,0,0,0,35,19,0,0,0,0,1,F2RL1;coagulation factor II (thrombin) receptor-like 1,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0031143//pseudopodium;GO:0005887//integral component of plasma membrane,"GO:0046330//positive regulation of JNK cascade;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0046328//regulation of JNK cascade;GO:0035025//positive regulation of Rho protein signal transduction;GO:0032930//positive regulation of superoxide anion generation;GO:0042119//neutrophil activation;GO:0050921//positive regulation of chemotaxis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0097029//mature dendritic cell differentiation;GO:0050927//positive regulation of positive chemotaxis;GO:0045087//innate immune response;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0072608//interleukin-10 secretion;GO:0034137//positive regulation of toll-like receptor 2 signaling pathway;GO:0007596//blood coagulation;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070963//positive regulation of neutrophil mediated killing of gram-negative bacterium;GO:0072643//interferon-gamma secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0002286//T cell activation involved in immune response;GO:2000484//positive regulation of interleukin-8 secretion;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0050702//interleukin-1 beta secretion;GO:1900135//positive regulation of renin secretion into blood stream;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030193//regulation of blood coagulation;GO:0061028//establishment of endothelial barrier;GO:0003104//positive regulation of glomerular filtration;GO:0046329//negative regulation of JNK cascade;GO:2000778//positive regulation of interleukin-6 secretion;GO:0031274//positive regulation of pseudopodium assembly;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0034140//negative regulation of toll-like receptor 3 signaling pathway;GO:0050900//leukocyte migration;GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0045909//positive regulation of vasodilation;GO:0030836//positive regulation of actin filament depolymerization;GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0070493//thrombin receptor signaling pathway;GO:0043311//positive regulation of eosinophil degranulation;GO:0006954//inflammatory response;GO:0090198//negative regulation of chemokine secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070661//leukocyte proliferation;GO:0035926//chemokine (C-C motif) ligand 2 secretion;GO:0051607//defense response to virus",GO:0015057//thrombin receptor activity;GO:0005515//protein binding;GO:0031681//G-protein beta-subunit binding;GO:0001965//G-protein alpha-subunit binding;GO:0004872//receptor activity;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity,K04234//African trypanosomiasis;Neuroactive ligand-receptor interaction
2151,0,0,0,0,0,0,0,0,28,0,0,0,F2RL2;coagulation factor II (thrombin) receptor-like 2,GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0007596//blood coagulation;GO:0008152//metabolic process;GO:0009611//response to wounding;GO:0070493//thrombin receptor signaling pathway;GO:0030168//platelet activation,GO:0005515//protein binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0015057//thrombin receptor activity,K04235//Neuroactive ligand-receptor interaction
2152,0,0,0,0,2,12,0,0,0,0,0,0,"F3;coagulation factor III (thromboplastin, tissue factor)",GO:0031233//intrinsic component of external side of plasma membrane;GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0009986//cell surface,"GO:0045766//positive regulation of angiogenesis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050927//positive regulation of positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0002541//activation of plasma proteins involved in acute inflammatory response;GO:0030335//positive regulation of cell migration;GO:0002543//activation of blood coagulation via clotting cascade;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007598//blood coagulation, extrinsic pathway;GO:0007596//blood coagulation;GO:0010641//positive regulation of platelet-derived growth factor receptor signaling pathway",GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0002020//protease binding,K03901//Complement and coagulation cascades
2153,108,0,0,0,0,27,13,0,52,0,0,0,"F5;coagulation factor V (proaccelerin, labile factor)",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0031982//vesicle,GO:0007596//blood coagulation;GO:0007155//cell adhesion;GO:0030168//platelet activation;GO:0008015//blood circulation;GO:0002576//platelet degranulation,GO:0005515//protein binding;GO:0005507//copper ion binding,K03902//Complement and coagulation cascades
2155,0,0,0,0,0,0,0,0,27,1,7,0,F7;coagulation factor VII (serum prothrombin conversion accelerator),GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0031982//vesicle;GO:0005788//endoplasmic reticulum lumen,"GO:0030335//positive regulation of cell migration;GO:0032571//response to vitamin K;GO:0060416//response to growth hormone;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0031100//organ regeneration;GO:0050927//positive regulation of positive chemotaxis;GO:0044267//cellular protein metabolic process;GO:0007623//circadian rhythm;GO:0043627//response to estrogen;GO:0006508//proteolysis;GO:0010641//positive regulation of platelet-derived growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0007598//blood coagulation, extrinsic pathway;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0030194//positive regulation of blood coagulation;GO:0043687//post-translational protein modification",GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004252//serine-type endopeptidase activity;GO:0005102//receptor binding;GO:0001948//glycoprotein binding;GO:0008236//serine-type peptidase activity,K01320//Complement and coagulation cascades
2157,0,0,0,23,23,37,8,0,52,0,16,288,"F8;coagulation factor VIII, procoagulant component",GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region,"GO:0030168//platelet activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0006953//acute-phase response;GO:0006508//proteolysis;GO:0002576//platelet degranulation;GO:0007155//cell adhesion",GO:0005507//copper ion binding;GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0004252//serine-type endopeptidase activity,K03899//Complement and coagulation cascades
2158,57,0,0,0,0,0,15,0,56,0,0,0,F9;coagulation factor IX,GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen,"GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0007597//blood coagulation, intrinsic pathway;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0043687//post-translational protein modification;GO:0007598//blood coagulation, extrinsic pathway;GO:0007596//blood coagulation",GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K01321//Complement and coagulation cascades
2159,0,0,0,0,0,0,11,0,26,13,6,0,F10;coagulation factor X,GO:0031233//intrinsic component of external side of plasma membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005576//extracellular region,"GO:0007598//blood coagulation, extrinsic pathway;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0007596//blood coagulation;GO:0006508//proteolysis;GO:0030335//positive regulation of cell migration;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0051897//positive regulation of protein kinase B signaling;GO:0007597//blood coagulation, intrinsic pathway",GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K01314//Complement and coagulation cascades
216,0,0,0,0,0,0,38,0,61,0,0,0,"ALDH1A1;aldehyde dehydrogenase 1 family, member A1",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0042572//retinol metabolic process;GO:0032320//positive regulation of Ras GTPase activity;GO:0006081//cellular aldehyde metabolic process;GO:0006069//ethanol oxidation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0001758//retinal dehydrogenase activity;GO:0005099//Ras GTPase activator activity;GO:0005497//androgen binding;GO:0004029//aldehyde dehydrogenase (NAD) activity,K07249//Metabolic pathways;Retinol metabolism
2160,0,0,0,0,0,19,0,0,52,0,8,0,F11;coagulation factor XI,GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0007596//blood coagulation;GO:0031639//plasminogen activation;GO:0006508//proteolysis;GO:0007597//blood coagulation, intrinsic pathway;GO:0051919//positive regulation of fibrinolysis",GO:0070009//serine-type aminopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding,K01323//Complement and coagulation cascades
2161,0,0,0,0,0,0,31,0,41,0,0,0,F12;coagulation factor XII (Hageman factor),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0042730//fibrinolysis;GO:0031638//zymogen activation;GO:0051788//response to misfolded protein;GO:0007596//blood coagulation;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0051919//positive regulation of fibrinolysis;GO:0010756//positive regulation of plasminogen activation;GO:0016485//protein processing;GO:0045087//innate immune response;GO:0030194//positive regulation of blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0002542//Factor XII activation",GO:0070009//serine-type aminopeptidase activity;GO:0051787//misfolded protein binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity,K01328//Complement and coagulation cascades
2162,0,0,0,0,0,28,104,0,2,0,30,0,"F13A1;coagulation factor XIII, A1 polypeptide",GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0031093//platelet alpha granule lumen,GO:0002576//platelet degranulation;GO:0030168//platelet activation;GO:0018149//peptide cross-linking;GO:0007596//blood coagulation,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding,K03917//Complement and coagulation cascades
2165,0,0,0,0,0,0,0,0,14,0,0,241,"F13B;coagulation factor XIII, B polypeptide",GO:0005576//extracellular region,GO:0007596//blood coagulation,-,K03906//Complement and coagulation cascades
2166,0,1,0,0,0,14,39,53,62,0,0,0,FAAH;fatty acid amide hydrolase,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0012505//endomembrane system;GO:0031090//organelle membrane;GO:0016021//integral component of membrane,GO:0009062//fatty acid catabolic process,"GO:0017064//fatty acid amide hydrolase activity;GO:0047372//acylglycerol lipase activity;GO:0016884//carbon-nitrogen ligase activity, with glutamine as amido-N-donor",K15528//Retrograde endocannabinoid signaling
2167,0,0,0,0,0,0,2,0,0,0,0,0,"FABP4;fatty acid binding protein 4, adipocyte",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005811//lipid particle,"GO:0001816//cytokine production;GO:0071285//cellular response to lithium ion;GO:0019433//triglyceride catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050873//brown fat cell differentiation;GO:0042632//cholesterol homeostasis;GO:0006810//transport;GO:0050729//positive regulation of inflammatory response;GO:0050872//white fat cell differentiation;GO:0044281//small molecule metabolic process;GO:0006469//negative regulation of protein kinase activity",GO:0005504//fatty acid binding;GO:0005215//transporter activity,K08753//PPAR signaling pathway
2168,0,0,0,0,0,11,0,0,4,0,0,0,"FABP1;fatty acid binding protein 1, liver",GO:0045179//apical cortex;GO:0005654//nucleoplasm;GO:0005782//peroxisomal matrix;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0070301//cellular response to hydrogen peroxide;GO:0051345//positive regulation of hydrolase activity;GO:0043066//negative regulation of apoptotic process;GO:0050892//intestinal absorption;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044255//cellular lipid metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0015909//long-chain fatty acid transport;GO:0044281//small molecule metabolic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0071456//cellular response to hypoxia,GO:0005504//fatty acid binding;GO:0032052//bile acid binding;GO:0003682//chromatin binding;GO:0008144//drug binding;GO:0005324//long-chain fatty acid transporter activity;GO:0005543//phospholipid binding;GO:0016209//antioxidant activity,K08750//Fat digestion and absorption;PPAR signaling pathway
2169,0,0,0,0,0,40,0,0,0,0,0,0,"FABP2;fatty acid binding protein 2, intestinal",GO:0005737//cytoplasm,GO:0007586//digestion;GO:0006810//transport,GO:0005215//transporter activity;GO:0005504//fatty acid binding,K08751//Fat digestion and absorption;PPAR signaling pathway
217,0,10,0,25,5,3,0,79,16,0,7,271,ALDH2;aldehyde dehydrogenase 2 family (mitochondrial),GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006068//ethanol catabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0007268//synaptic transmission;GO:0006069//ethanol oxidation;GO:0006066//alcohol metabolic process,GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0009055//electron carrier activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity,"K00128//Microbial metabolism in diverse environments;Histidine metabolism;Ascorbate and aldarate metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites;Pentose and glucuronate interconversions;Metabolic pathways;Propanoate metabolism;Pyruvate metabolism;Two-component system;Chloroalkane and chloroalkene degradation;Lysine degradation;Fatty acid metabolism;Arginine and proline metabolism;Glycolysis / Gluconeogenesis;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Glycerolipid metabolism;Bacterial chemotaxis;Limonene and pinene degradation"
2170,0,0,0,37,30,10,0,0,12,0,60,0,"FABP3;fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)",GO:0016528//sarcoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0055091//phospholipid homeostasis;GO:0032868//response to insulin;GO:0042493//response to drug;GO:0044539//long-chain fatty acid import;GO:0071073//positive regulation of phospholipid biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0070542//response to fatty acid;GO:0046320//regulation of fatty acid oxidation;GO:0008285//negative regulation of cell proliferation;GO:0042632//cholesterol homeostasis,GO:0008092//cytoskeletal protein binding;GO:0050543//icosatetraenoic acid binding;GO:0005515//protein binding;GO:0070538//oleic acid binding;GO:0005324//long-chain fatty acid transporter activity,K08752//PPAR signaling pathway
2171,0,0,22,6,0,0,0,0,6,0,0,0,FABP5;fatty acid binding protein 5 (psoriasis-associated),GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006629//lipid metabolic process;GO:0015758//glucose transport;GO:0008544//epidermis development;GO:0006006//glucose metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0009611//response to wounding,GO:0005515//protein binding;GO:0005504//fatty acid binding;GO:0005215//transporter activity;GO:0008289//lipid binding,K08754//PPAR signaling pathway
2172,0,0,0,0,0,0,0,0,19,0,5,0,"FABP6;fatty acid binding protein 6, ileal",GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0008206//bile acid metabolic process;GO:0044281//small molecule metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0015721//bile acid and bile salt transport;GO:0006629//lipid metabolic process,GO:0005215//transporter activity;GO:0008289//lipid binding,K08755//PPAR signaling pathway
2173,0,0,0,0,0,0,0,0,12,0,1,0,"FABP7;fatty acid binding protein 7, brain",GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0042995//cell projection;GO:0005634//nucleus,GO:0008285//negative regulation of cell proliferation;GO:0007399//nervous system development;GO:0050673//epithelial cell proliferation;GO:0021846//cell proliferation in forebrain;GO:0006810//transport;GO:0022008//neurogenesis;GO:0060134//prepulse inhibition,GO:0008289//lipid binding;GO:0005215//transporter activity,K08756//PPAR signaling pathway
2175,207,2,0,56,46,0,79,89,125,104,233,1,"FANCA;Fanconi anemia, complementation group A",GO:0005730//nucleolus;GO:0043240//Fanconi anaemia nuclear complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006461//protein complex assembly;GO:0008585//female gonad development;GO:0042127//regulation of cell proliferation;GO:0007140//male meiosis;GO:0006281//DNA repair;GO:0008584//male gonad development,GO:0005515//protein binding,K10888//Fanconi anemia pathway
2176,124,0,0,0,14,15,0,0,60,0,39,0,"FANCC;Fanconi anemia, complementation group C",GO:0043240//Fanconi anaemia nuclear complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006281//DNA repair;GO:0002262//myeloid cell homeostasis;GO:0019430//removal of superoxide radicals;GO:0006461//protein complex assembly;GO:0006289//nucleotide-excision repair;GO:0007281//germ cell development,GO:0005515//protein binding,K10890//Fanconi anemia pathway
2177,0,0,0,2,0,89,0,0,159,47,11,0,"FANCD2;Fanconi anemia, complementation group D2",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0000793//condensed chromosome;GO:0043231//intracellular membrane-bounded organelle,GO:0006281//DNA repair;GO:0007129//synapsis;GO:0007276//gamete generation;GO:0010332//response to gamma radiation,GO:0070182//DNA polymerase binding;GO:0005515//protein binding,K10891//Fanconi anemia pathway
2178,0,20,0,0,34,0,0,69,1,0,0,0,"FANCE;Fanconi anemia, complementation group E",GO:0043240//Fanconi anaemia nuclear complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006281//DNA repair,-,K10892//Fanconi anemia pathway
218,2,0,0,0,4,20,0,2,51,0,0,0,"ALDH3A1;aldehyde dehydrogenase 3 family, member A1",GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0051591//response to cAMP;GO:0007568//aging;GO:0042493//response to drug;GO:0008284//positive regulation of cell proliferation;GO:0051384//response to glucocorticoid;GO:0001666//response to hypoxia;GO:0006081//cellular aldehyde metabolic process;GO:0055114//oxidation-reduction process;GO:0007584//response to nutrient,GO:0008106//alcohol dehydrogenase (NADP+) activity;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity,K00129//Tyrosine metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;beta-Alanine metabolism;Metabolism of xenobiotics by cytochrome P450;Phenylalanine metabolism;Microbial metabolism in diverse environments;Histidine metabolism;Glycolysis / Gluconeogenesis
2180,109,142,5,175,280,0,0,1,25,0,1,936,ACSL1;acyl-CoA synthetase long-chain family member 1,GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane;GO:0005741//mitochondrial outer membrane,GO:0033211//adiponectin-activated signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0042493//response to drug;GO:0008610//lipid biosynthetic process;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0044281//small molecule metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0043651//linoleic acid metabolic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0042178//xenobiotic catabolic process;GO:0014070//response to organic cyclic compound;GO:0044539//long-chain fatty acid import;GO:0034201//response to oleic acid;GO:0007584//response to nutrient;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process,GO:0005524//ATP binding;GO:0004467//long-chain fatty acid-CoA ligase activity,K01897//Metabolic pathways;Adipocytokine signaling pathway;PPAR signaling pathway;Ribosome;Fatty acid metabolism;Peroxisome
2181,0,30,1,17,10,11,0,5,19,73,12,0,ACSL3;acyl-CoA synthetase long-chain family member 3,GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005778//peroxisomal membrane,GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0001676//long-chain fatty acid metabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:0014070//response to organic cyclic compound;GO:0006633//fatty acid biosynthetic process;GO:0044539//long-chain fatty acid import;GO:2001247//positive regulation of phosphatidylcholine biosynthetic process;GO:0007420//brain development;GO:0051047//positive regulation of secretion;GO:0007584//response to nutrient,GO:0019901//protein kinase binding;GO:0005524//ATP binding;GO:0019904//protein domain specific binding;GO:0004467//long-chain fatty acid-CoA ligase activity,K01897//Fatty acid metabolism;Peroxisome;Ribosome;Adipocytokine signaling pathway;PPAR signaling pathway;Metabolic pathways
2182,0,0,0,6,37,14,17,0,30,0,0,0,ACSL4;acyl-CoA synthetase long-chain family member 4,GO:0005789//endoplasmic reticulum membrane;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005778//peroxisomal membrane;GO:0005811//lipid particle;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0001676//long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0008610//lipid biosynthetic process;GO:0070672//response to interleukin-15;GO:0032307//negative regulation of prostaglandin secretion;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0015908//fatty acid transport;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0030307//positive regulation of cell growth;GO:0007584//response to nutrient;GO:0060136//embryonic process involved in female pregnancy;GO:0060996//dendritic spine development,GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0047676//arachidonate-CoA ligase activity;GO:0005524//ATP binding;GO:0031957//very long-chain fatty acid-CoA ligase activity,K01897//PPAR signaling pathway;Adipocytokine signaling pathway;Metabolic pathways;Peroxisome;Fatty acid metabolism;Ribosome
2184,40,0,0,0,0,10,0,0,1,0,0,42,FAH;fumarylacetoacetate hydrolase (fumarylacetoacetase),GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006572//tyrosine catabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0006527//arginine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process,GO:0004334//fumarylacetoacetase activity;GO:0046872//metal ion binding,K01555//Metabolic pathways;Microbial metabolism in diverse environments;Tyrosine metabolism;Styrene degradation
2185,0,36,0,4,30,0,25,0,88,5,37,0,PTK2B;protein tyrosine kinase 2 beta,GO:0005730//nucleolus;GO:0030424//axon;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0044297//cell body;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0045121//membrane raft;GO:0097440//apical dendrite;GO:0030027//lamellipodium;GO:0043025//neuronal cell body,"GO:0042220//response to cocaine;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0002040//sprouting angiogenesis;GO:0008284//positive regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042542//response to hydrogen peroxide;GO:0008360//regulation of cell shape;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0043267//negative regulation of potassium ion transport;GO:0010595//positive regulation of endothelial cell migration;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0006950//response to stress;GO:0007166//cell surface receptor signaling pathway;GO:0031175//neuron projection development;GO:0030502//negative regulation of bone mineralization;GO:0007229//integrin-mediated signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0010976//positive regulation of neuron projection development;GO:0048041//focal adhesion assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0043534//blood vessel endothelial cell migration;GO:0045453//bone resorption;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0043507//positive regulation of JUN kinase activity;GO:0006968//cellular defense response;GO:2000538//positive regulation of B cell chemotaxis;GO:0032960//regulation of inositol trisphosphate biosynthetic process;GO:0009749//response to glucose;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0014009//glial cell proliferation;GO:0010226//response to lithium ion;GO:0006461//protein complex assembly;GO:0046330//positive regulation of JNK cascade;GO:0001954//positive regulation of cell-matrix adhesion;GO:0030307//positive regulation of cell growth;GO:0001556//oocyte maturation;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0007173//epidermal growth factor receptor signaling pathway;GO:2000114//regulation of establishment of cell polarity;GO:0051592//response to calcium ion;GO:0002315//marginal zone B cell differentiation;GO:0071300//cellular response to retinoic acid;GO:0042976//activation of Janus kinase activity;GO:0060291//long-term synaptic potentiation;GO:0043149//stress fiber assembly;GO:0030155//regulation of cell adhesion;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007172//signal complex assembly;GO:0042493//response to drug;GO:0045638//negative regulation of myeloid cell differentiation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0045471//response to ethanol;GO:0000165//MAPK cascade;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0007165//signal transduction;GO:0009725//response to hormone;GO:0046777//protein autophosphorylation;GO:0006970//response to osmotic stress;GO:0051591//response to cAMP;GO:0045727//positive regulation of translation;GO:0032863//activation of Rac GTPase activity;GO:0006468//protein phosphorylation;GO:0010758//regulation of macrophage chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0001666//response to hypoxia;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus",GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0004871//signal transducer activity;GO:0043423//3-phosphoinositide-dependent protein kinase binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0004683//calmodulin-dependent protein kinase activity;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity,K05871//Leukocyte transendothelial migration;Calcium signaling pathway;Chemokine signaling pathway;GnRH signaling pathway;Natural killer cell mediated cytotoxicity
2186,0,84,29,114,311,34,39,48,105,31,3,0,BPTF;bromodomain PHD finger transcription factor,GO:0016589//NURF complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0001892//embryonic placenta development;GO:0006200//ATP catabolic process;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007492//endoderm development;GO:0007420//brain development",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0008094//DNA-dependent ATPase activity,-
2187,0,0,0,0,0,0,26,0,0,0,0,0,"FANCB;Fanconi anemia, complementation group B",GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex,GO:0006281//DNA repair,GO:0005515//protein binding,K10889//Fanconi anemia pathway
2188,0,0,0,23,13,0,0,28,5,0,32,0,"FANCF;Fanconi anemia, complementation group F",GO:0043240//Fanconi anaemia nuclear complex;GO:0005654//nucleoplasm,GO:0016567//protein ubiquitination;GO:0007283//spermatogenesis;GO:0006281//DNA repair;GO:0001541//ovarian follicle development,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10893//Fanconi anemia pathway
2189,40,40,0,13,4,14,0,40,7,0,17,0,"FANCG;Fanconi anemia, complementation group G",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0043240//Fanconi anaemia nuclear complex;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0006281//DNA repair;GO:0007005//mitochondrion organization;GO:0000075//cell cycle checkpoint;GO:0009314//response to radiation;GO:0001541//ovarian follicle development;GO:0007286//spermatid development,GO:0005515//protein binding;GO:0003684//damaged DNA binding,K10894//Fanconi anemia pathway
219,0,1,0,5,38,1,13,0,26,0,0,0,"ALDH1B1;aldehyde dehydrogenase 1 family, member B1",GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle,GO:0005975//carbohydrate metabolic process;GO:0055114//oxidation-reduction process;GO:0006068//ethanol catabolic process,GO:0004029//aldehyde dehydrogenase (NAD) activity,"K00128//Two-component system;Pentose and glucuronate interconversions;Metabolic pathways;Pyruvate metabolism;Propanoate metabolism;Lysine degradation;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Arginine and proline metabolism;Ascorbate and aldarate metabolism;Histidine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Tryptophan metabolism;Glycerolipid metabolism;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Bacterial chemotaxis;Limonene and pinene degradation;Glycolysis / Gluconeogenesis"
2191,0,63,89,221,135,0,53,0,44,0,104,0,"FAP;fibroblast activation protein, alpha",GO:0045178//basal part of cell;GO:0045177//apical part of cell;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0071438//invadopodium membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0005615//extracellular space;GO:0032587//ruffle membrane,GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0051917//regulation of fibrinolysis;GO:0071158//positive regulation of cell cycle arrest;GO:1900119//positive regulation of execution phase of apoptosis;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0071850//mitotic cell cycle arrest;GO:0043542//endothelial cell migration,GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0042803//protein homodimerization activity;GO:0004252//serine-type endopeptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0004175//endopeptidase activity;GO:0002020//protease binding,-
2192,78,0,0,0,0,0,0,129,24,0,1,0,FBLN1;fibulin 1,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space,GO:0007566//embryo implantation;GO:0010952//positive regulation of peptidase activity;GO:0016032//viral process;GO:0030198//extracellular matrix organization,GO:0016504//peptidase activator activity;GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding,K08023//TGF-beta signaling pathway
219285,0,0,0,0,1,25,0,58,29,0,0,0,SAMD9L;sterile alpha motif domain containing 9-like,GO:0005769//early endosome,GO:0002244//hematopoietic progenitor cell differentiation;GO:0048536//spleen development;GO:0042176//regulation of protein catabolic process;GO:0017145//stem cell division;GO:0035726//common myeloid progenitor cell proliferation,-,-
219287,0,0,0,0,0,10,36,0,51,0,0,0,AMER2;APC membrane recruitment protein 2,GO:0005886//plasma membrane,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007398//ectoderm development,"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
219293,0,0,1,0,0,0,21,0,55,0,15,0,"ATAD3C;ATPase family, AAA domain containing 3C",-,-,GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
2193,68,0,1,0,0,0,0,1,20,0,4,1,"FARSA;phenylalanyl-tRNA synthetase, alpha subunit",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005829//cytosol,GO:0006432//phenylalanyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0044822//poly(A) RNA binding;GO:0004826//phenylalanine-tRNA ligase activity;GO:0005515//protein binding;GO:0000049//tRNA binding;GO:0005524//ATP binding,"K01889//Biosynthesis of secondary metabolites;C5-Branched dibasic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Aminoacyl-tRNA biosynthesis;ABC transporters"
219333,0,1,0,18,51,31,0,0,0,0,0,0,USP12;ubiquitin specific peptidase 12,-,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity,-
219348,0,0,0,8,17,0,0,0,0,0,0,0,PLAC9;placenta-specific 9,GO:0005576//extracellular region,-,-,-
2194,99,7,4,35,54,4,66,6,91,0,40,343,FASN;fatty acid synthase,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0042587//glycogen granule;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0042470//melanosome;GO:0005737//cytoplasm,GO:0015939//pantothenate metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0006112//energy reserve metabolic process;GO:0031325//positive regulation of cellular metabolic process;GO:0006766//vitamin metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0071353//cellular response to interleukin-4;GO:0001649//osteoblast differentiation;GO:0019432//triglyceride biosynthetic process;GO:0006084//acetyl-CoA metabolic process;GO:0006633//fatty acid biosynthetic process,"GO:0004317//3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity;GO:0008144//drug binding;GO:0047117//enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity;GO:0004313//[acyl-carrier-protein] S-acetyltransferase activity;GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity;GO:0042803//protein homodimerization activity;GO:0047451//3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity;GO:0004316//3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity;GO:0070402//NADPH binding;GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity;GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0008270//zinc ion binding;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004319//enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity;GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity",K00665//Fatty acid biosynthesis;Insulin signaling pathway;Metabolic pathways
219402,0,76,32,116,125,0,0,0,16,0,130,0,MTIF3;mitochondrial translational initiation factor 3,GO:0005739//mitochondrion,GO:0032790//ribosome disassembly;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0006446//regulation of translational initiation,"GO:0003743//translation initiation factor activity;GO:0043024//ribosomal small subunit binding;GO:0008135//translation factor activity, nucleic acid binding",-
219409,0,0,0,0,0,15,0,0,27,0,0,0,GSX1;GS homeobox 1,GO:0005634//nucleus,"GO:0048663//neuron fate commitment;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021854//hypothalamus development;GO:0021984//adenohypophysis development;GO:0021527//spinal cord association neuron differentiation",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding,-
219428,56,0,0,0,0,0,0,0,26,0,0,0,"OR4C16;olfactory receptor, family 4, subfamily C, member 16",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219432,0,0,0,0,0,0,0,0,22,0,0,0,"OR4C6;olfactory receptor, family 4, subfamily C, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219436,0,0,0,0,0,0,0,0,16,0,0,0,"OR5D14;olfactory receptor, family 5, subfamily D, member 14",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219437,0,0,0,0,0,0,0,0,7,0,0,0,"OR5L1;olfactory receptor, family 5, subfamily L, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219438,0,0,0,0,0,0,18,0,0,0,2,0,"OR5D18;olfactory receptor, family 5, subfamily D, member 18",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219445,0,0,0,0,0,0,0,0,28,0,0,0,"OR7E5P;olfactory receptor, family 7, subfamily E, member 5 pseudogene",-,-,-,K04257//Olfactory transduction
219453,0,0,0,0,0,0,0,0,8,0,0,0,"OR8K5;olfactory receptor, family 8, subfamily K, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219464,0,0,0,0,0,0,0,64,7,0,0,0,"OR5T2;olfactory receptor, family 5, subfamily T, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219473,0,0,0,0,0,0,0,0,12,0,0,0,"OR8K3;olfactory receptor, family 8, subfamily K, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219477,0,0,0,0,0,0,0,0,19,0,0,0,"OR8J1;olfactory receptor, family 8, subfamily J, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219479,0,0,0,0,0,8,21,0,1,0,0,0,"OR5R1;olfactory receptor, family 5, subfamily R, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219484,5,0,0,0,0,0,0,0,10,0,0,0,"OR5M8;olfactory receptor, family 5, subfamily M, member 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219487,0,0,0,0,0,0,0,0,8,0,0,0,"OR5M11;olfactory receptor, family 5, subfamily M, member 11",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2195,61,59,0,21,31,17,0,0,85,0,0,0,FAT1;FAT atypical cadherin 1,GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0005911//cell-cell junction,GO:0007163//establishment or maintenance of cell polarity;GO:0016337//single organismal cell-cell adhesion;GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007267//cell-cell signaling;GO:0016477//cell migration,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
219527,0,0,0,0,0,0,0,0,42,0,0,0,LRRC55;leucine rich repeat containing 55,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport,-,K06850//Axon guidance;K06839//Axon guidance
219537,0,0,0,0,0,14,0,0,0,0,0,0,SMTNL1;smoothelin-like 1,GO:0005634//nucleus;GO:0043292//contractile fiber;GO:0031430//M band;GO:0005737//cytoplasm;GO:0031674//I band,GO:0045907//positive regulation of vasoconstriction;GO:0045908//negative regulation of vasodilation,GO:0005516//calmodulin binding,K05699//Adherens junction;Focal adhesion;Amoebiasis;Systemic lupus erythematosus;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
219539,0,0,0,0,0,7,0,0,31,0,2,0,YPEL4;yippee-like 4 (Drosophila),GO:0005730//nucleolus,-,-,-
219541,62,18,0,0,4,0,0,0,0,0,0,0,MED19;mediator complex subunit 19,GO:0016592//mediator complex;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0001104//RNA polymerase II transcription cofactor activity,-
219557,0,0,0,0,0,0,22,0,0,0,0,0,C7orf62;chromosome 7 open reading frame 62,-,-,-,-
219578,0,0,0,0,0,0,0,0,8,0,0,0,ZNF804B;zinc finger protein 804B,-,-,GO:0046872//metal ion binding,-
219595,0,0,0,0,0,10,0,0,67,0,0,0,FOLH1B;folate hydrolase 1B,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0016805//dipeptidase activity;GO:0008237//metallopeptidase activity;GO:0046872//metal ion binding,K14592//Vitamin digestion and absorption
2196,101,44,0,23,29,93,12,0,82,0,44,0,FAT2;FAT atypical cadherin 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005913//cell-cell adherens junction;GO:0005634//nucleus,GO:0010631//epithelial cell migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
219621,0,25,0,0,19,30,0,0,59,0,0,0,C10orf107;chromosome 10 open reading frame 107,-,-,-,-
219623,0,0,0,0,6,5,6,10,59,0,0,0,TMEM26;transmembrane protein 26,GO:0016021//integral component of membrane,-,-,-
219654,0,0,0,6,10,9,11,92,27,0,28,0,"ZCCHC24;zinc finger, CCHC domain containing 24",-,-,GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
219670,0,0,0,0,0,0,0,0,63,35,0,0,"ENKUR;enkurin, TRPC channel interacting protein",GO:0031514//motile cilium,-,GO:0005516//calmodulin binding;GO:0017124//SH3 domain binding,-
219681,0,0,0,0,0,0,13,62,23,0,9,0,ARMC3;armadillo repeat containing 3,GO:0070062//extracellular vesicular exosome,-,-,K10056//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Acute myeloid leukemia;Transcriptional misregulation in cancer;K02105//Leukocyte transendothelial migration;Tight junction;Bacterial invasion of epithelial cells;HTLV-I infection;Pathogenic Escherichia coli infection;Thyroid cancer;Melanogenesis;Focal adhesion;Endometrial cancer;Prostate cancer;Basal cell carcinoma;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Adherens junction;Colorectal cancer;Wnt signaling pathway
219699,104,0,0,0,0,22,31,0,85,0,21,0,UNC5B;unc-5 homolog B (C. elegans),GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0043524//negative regulation of neuron apoptotic process;GO:0042981//regulation of apoptotic process;GO:0007411//axon guidance;GO:0043065//positive regulation of apoptotic process;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0006915//apoptotic process;GO:0033564//anterior/posterior axon guidance;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005515//protein binding,K07521//Axon guidance
2197,0,45,41,36,164,0,0,0,7,0,0,0,FAU;Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed,GO:0022627//cytosolic small ribosomal subunit;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0015935//small ribosomal subunit,"GO:0019731//antibacterial humoral response;GO:0006412//translation;GO:0010467//gene expression;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0002227//innate immune response in mucosa;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02983//Ribosome
219731,2,0,0,0,11,0,0,40,27,0,0,0,PROSER2-AS1;PROSER2 antisense RNA 1,-,-,-,-
219736,1,0,0,0,1,0,14,0,37,0,6,1,STOX1;storkhead box 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0003677//DNA binding,-
219738,0,0,0,0,13,36,0,0,0,0,0,0,C10orf35;chromosome 10 open reading frame 35,GO:0016021//integral component of membrane,-,-,-
219743,0,0,0,0,0,0,0,3,6,0,0,0,TYSND1;trypsin domain containing 1,GO:0005777//peroxisome;GO:0016020//membrane,GO:0006508//proteolysis;GO:0031998//regulation of fatty acid beta-oxidation;GO:0051260//protein homooligomerization;GO:0016485//protein processing,GO:0042802//identical protein binding;GO:0004252//serine-type endopeptidase activity;GO:0002020//protease binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
219749,0,0,0,10,42,0,0,0,34,0,0,0,ZNF25;zinc finger protein 25,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
219770,86,0,0,0,0,23,0,0,0,0,18,0,"GJD4;gap junction protein, delta 4, 40.1kDa",GO:0016021//integral component of membrane;GO:0005922//connexon complex,GO:0007154//cell communication,-,-
219771,36,0,1,24,58,21,14,0,31,0,0,0,CCNY;cyclin Y,GO:0000308//cytoplasmic cyclin-dependent protein kinase holoenzyme complex;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0016055//Wnt signaling pathway;GO:0000086//G2/M transition of mitotic cell cycle;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0051301//cell division;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
219790,0,0,0,6,21,10,86,0,20,0,0,0,RTKN2;rhotekin 2,GO:0005886//plasma membrane,GO:0008284//positive regulation of cell proliferation;GO:0030097//hemopoiesis;GO:0007165//signal transduction,-,-
219793,0,1,0,0,0,0,0,0,37,0,17,0,"TBATA;thymus, brain and testes associated",GO:0005634//nucleus;GO:0005829//cytosol,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,-,-
219833,0,0,0,0,0,14,21,0,13,52,0,444,C11orf45;chromosome 11 open reading frame 45,GO:0005576//extracellular region,-,-,K04995//Aldosterone-regulated sodium reabsorption;Gastric acid secretion
219844,188,0,0,19,22,1,0,0,36,0,9,0,HYLS1;hydrolethalus syndrome 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005886//plasma membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
219855,61,0,0,0,0,1,23,0,33,0,21,26,"SLC37A2;solute carrier family 37 (glucose-6-phosphate transporter), member 2",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
219858,49,0,0,0,0,0,0,0,5,0,0,0,"OR8B12;olfactory receptor, family 8, subfamily B, member 12",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219865,0,0,0,0,0,0,0,0,0,0,15,0,"OR8G5;olfactory receptor, family 8, subfamily G, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219870,0,0,0,0,0,0,40,0,0,0,0,0,"OR10G9;olfactory receptor, family 10, subfamily G, member 9",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219873,0,0,0,0,0,0,0,0,8,0,0,0,"OR10S1;olfactory receptor, family 10, subfamily S, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219874,0,0,0,0,0,0,0,3,0,0,0,0,"OR6T1;olfactory receptor, family 6, subfamily T, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219899,0,17,2,22,35,0,0,0,36,0,3,0,TBCEL;tubulin folding cofactor E-like,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,-,K11092//Spliceosome
2199,0,0,0,0,0,0,32,2,18,109,16,0,FBLN2;fibulin 2,GO:0031012//extracellular matrix;GO:0031982//vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion,GO:0005509//calcium ion binding;GO:0005201//extracellular matrix structural constituent;GO:0050840//extracellular matrix binding,K08023//TGF-beta signaling pathway
219902,0,0,0,9,0,39,0,0,5,0,0,0,TMEM136;transmembrane protein 136,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
219927,0,0,0,4,69,0,0,0,13,0,0,0,MRPL21;mitochondrial ribosomal protein L21,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
219931,0,0,0,0,7,13,0,62,84,74,0,0,TPCN2;two pore segment channel 2,GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane,GO:0086010//membrane depolarization during action potential;GO:0006939//smooth muscle contraction;GO:0006874//cellular calcium ion homeostasis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport,GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0072345//NAADP-sensitive calcium-release channel activity,K14077//Pancreatic secretion
219938,131,0,0,0,18,16,0,0,0,0,0,0,SPATA19;spermatogenesis associated 19,GO:0005741//mitochondrial outer membrane,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,-
219954,0,0,0,0,0,0,0,0,3,0,0,0,"OR9I1;olfactory receptor, family 9, subfamily I, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219956,0,0,0,0,0,0,0,0,18,0,0,0,"OR9Q1;olfactory receptor, family 9, subfamily Q, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219957,0,0,0,0,0,27,0,27,0,0,0,1,"OR9Q2;olfactory receptor, family 9, subfamily Q, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219960,0,0,0,0,0,0,0,9,17,0,0,0,"OR10Q1;olfactory receptor, family 10, subfamily Q, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219965,0,0,0,0,0,0,22,0,0,0,0,0,"OR5B17;olfactory receptor, family 5, subfamily B, member 17",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219968,0,0,0,0,0,0,0,0,67,0,0,0,"OR5B21;olfactory receptor, family 5, subfamily B, member 21",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219970,0,0,0,0,0,32,0,0,18,0,9,0,GLYATL2;glycine-N-acyltransferase-like 2,GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0047961//glycine N-acyltransferase activity,K00628//Phenylalanine metabolism;K15517//Phenylalanine metabolism
219972,0,0,0,0,0,0,7,0,31,0,9,0,MPEG1;macrophage expressed 1,GO:0016021//integral component of membrane,-,-,-
219981,0,0,0,0,0,0,0,0,0,46,0,0,"OR5A2;olfactory receptor, family 5, subfamily A, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
219982,0,0,0,0,0,0,0,0,18,0,10,0,"OR5A1;olfactory receptor, family 5, subfamily A, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
219988,0,0,1,23,53,0,0,1,36,0,32,0,PATL1;protein associated with topoisomerase II homolog 1 (yeast),GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0016605//PML body;GO:0030014//CCR4-NOT complex;GO:0000932//cytoplasmic mRNA processing body,"GO:0016071//mRNA metabolic process;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0010467//gene expression;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0034046//poly(G) binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0003723//RNA binding,K12617//RNA degradation
219995,0,0,0,0,0,0,0,0,31,0,6,0,"MS4A15;membrane-spanning 4-domains, subfamily A, member 15",GO:0016021//integral component of membrane,-,-,K06466//Hematopoietic cell lineage;K08090//Asthma;Fc epsilon RI signaling pathway
22,59,0,0,0,3,18,32,1,0,0,0,0,"ABCB7;ATP-binding cassette, sub-family B (MDR/TAP), member 7",GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0006810//transport;GO:0015886//heme transport;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport,"GO:0015232//heme transporter activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding",K05662//ABC transporters
220,286,155,6,246,379,16,3,0,22,1,50,0,"ALDH1A3;aldehyde dehydrogenase 1 family, member A3",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0060166//olfactory pit development;GO:0042573//retinoic acid metabolic process;GO:0042472//inner ear morphogenesis;GO:0007626//locomotory behavior;GO:0042572//retinol metabolic process;GO:0050885//neuromuscular process controlling balance;GO:0060324//face development;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:0043065//positive regulation of apoptotic process;GO:0002138//retinoic acid biosynthetic process;GO:0042574//retinal metabolic process;GO:0060013//righting reflex;GO:0055114//oxidation-reduction process;GO:0048048//embryonic eye morphogenesis;GO:0021768//nucleus accumbens development,GO:0070324//thyroid hormone binding;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0070403//NAD+ binding;GO:0042803//protein homodimerization activity;GO:0004029//aldehyde dehydrogenase (NAD) activity,K07249//Metabolic pathways;Retinol metabolism;K00129//Histidine metabolism;Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Drug metabolism - cytochrome P450;beta-Alanine metabolism;Metabolic pathways;Tyrosine metabolism;Phenylalanine metabolism;Metabolism of xenobiotics by cytochrome P450
2200,21,0,0,0,0,54,7,44,162,124,10,308,FBN1;fibrillin 1,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0001527//microfibril;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005604//basement membrane,GO:0001501//skeletal system development;GO:0035582//sequestering of BMP in extracellular matrix;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0007507//heart development;GO:0001822//kidney development,GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
220001,0,0,0,0,0,0,0,0,33,0,3,269,VWCE;von Willebrand factor C and EGF domains,GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,-
220002,0,0,0,0,0,1,0,0,2,0,0,0,"CYB561A3;cytochrome b561 family, member A3",GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0005765//lysosomal membrane,GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity,K08370//Mineral absorption
220004,0,0,0,0,7,0,0,0,57,0,0,2,"PPP1R32;protein phosphatase 1, regulatory subunit 32",-,-,GO:0005515//protein binding;GO:0019902//phosphatase binding,-
220032,0,0,0,0,0,27,0,0,52,0,0,0,GDPD4;glycerophosphodiester phosphodiesterase domain containing 4,GO:0016021//integral component of membrane,GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process,GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0046872//metal ion binding,-
220042,0,0,0,0,0,8,29,55,0,0,0,0,DDIAS;DNA damage-induced apoptosis suppressor,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071447//cellular response to hydroperoxide;GO:0034644//cellular response to UV;GO:0006915//apoptotic process;GO:0030097//hemopoiesis;GO:0071480//cellular response to gamma radiation;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0007286//spermatid development;GO:0006974//cellular response to DNA damage stimulus;GO:0071345//cellular response to cytokine stimulus;GO:0071850//mitotic cell cycle arrest,-,-
220047,0,0,0,0,0,1,17,0,39,0,0,0,CCDC83;coiled-coil domain containing 83,-,-,-,-
220064,72,0,0,6,0,0,0,0,0,45,0,0,ORAOV1;oral cancer overexpressed 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
220070,0,0,0,0,0,0,0,3,8,0,0,0,SHANK2-AS3;SHANK2 antisense RNA 3,-,-,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
220074,16,712,266,438,673,0,19,418,175,178,994,0,LRTOMT;leucine rich transmembrane and O-methyltransferase domain containing,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0042424//catecholamine catabolic process;GO:0007605//sensory perception of sound;GO:0060117//auditory receptor cell development;GO:0032259//methylation;GO:0042135//neurotransmitter catabolic process,GO:0016206//catechol O-methyltransferase activity,K00545//Dopaminergic synapse;Tyrosine metabolism;Metabolic pathways;Steroid hormone biosynthesis;Betalain biosynthesis;K11447//Transcriptional misregulation in cancer
220081,16,0,0,0,0,22,39,0,24,0,0,70,ERICH6B;glutamate-rich 6B,-,-,-,-
220082,0,0,0,2,0,0,0,67,12,0,0,0,SPERT;spermatid associated,GO:0016023//cytoplasmic membrane-bounded vesicle,-,-,-
2201,197,43,0,48,7,47,0,44,123,0,25,293,FBN2;fibrillin 2,GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0001527//microfibril,GO:0030501//positive regulation of bone mineralization;GO:0045669//positive regulation of osteoblast differentiation;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0030326//embryonic limb morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0060346//bone trabecula formation;GO:0035583//sequestering of TGFbeta in extracellular matrix,GO:0005509//calcium ion binding;GO:0005201//extracellular matrix structural constituent,-
220107,0,0,0,0,0,0,0,0,0,71,16,0,"DLEU7;deleted in lymphocytic leukemia, 7",-,-,-,-
220108,0,0,0,9,1,8,17,0,31,0,0,0,FAM124A;family with sequence similarity 124A,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
220115,0,0,0,0,0,4,15,0,17,0,0,0,TPTE2P3;transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 3,-,-,-,K01110//Focal adhesion;Inositol phosphate metabolism;p53 signaling pathway;Glioma;Melanoma;Endometrial cancer;Small cell lung cancer;Prostate cancer;Tight junction;Phosphatidylinositol signaling system;Pathways in cancer
220134,0,0,1,0,0,0,0,0,43,0,1,0,SKA1;spindle and kinetochore associated complex subunit 1,GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton,GO:0051301//cell division;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation,GO:0008017//microtubule binding;GO:0005515//protein binding,K06264//ECM-receptor interaction;K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
220136,0,0,0,0,0,0,0,0,13,0,0,0,CCDC11;coiled-coil domain containing 11,-,-,-,K05702//Adherens junction;Leukocyte transendothelial migration;Tight junction;K11423//Lysine degradation
220158,0,0,0,0,0,0,0,0,27,0,0,0,"GTSCR1;Gilles de la Tourette syndrome chromosome region, candidate 1 (non-protein coding)",GO:0016021//integral component of membrane,-,-,-
220164,0,0,0,0,0,19,25,78,48,0,0,0,DOK6;docking protein 6,-,-,GO:0005515//protein binding;GO:0005158//insulin receptor binding,K14752//Measles
2202,0,0,1,0,9,6,20,0,28,0,0,0,EFEMP1;EGF containing fibulin-like extracellular matrix protein 1,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,"GO:0007601//visual perception;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032331//negative regulation of chondrocyte differentiation;GO:0030198//extracellular matrix organization",GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0005006//epidermal growth factor-activated receptor activity;GO:0005509//calcium ion binding;GO:0008083//growth factor activity,K08023//TGF-beta signaling pathway
220202,0,0,0,0,0,0,0,0,29,0,0,0,ATOH7;atonal homolog 7 (Drosophila),GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0021554//optic nerve development;GO:0007623//circadian rhythm;GO:0009649//entrainment of circadian clock;GO:0030154//cell differentiation;GO:0003407//neural retina development;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
220213,0,0,0,0,12,0,46,0,24,0,0,0,OTUD1;OTU deubiquitinase 1,-,GO:0070536//protein K63-linked deubiquitination;GO:0006508//proteolysis,GO:0004843//ubiquitin-specific protease activity,-
220296,0,1,0,0,0,8,24,0,14,0,0,0,HEPACAM;hepatic and glial cell adhesion molecule,GO:0030424//axon;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0040008//regulation of growth;GO:0034613//cellular protein localization;GO:0007050//cell cycle arrest;GO:0007155//cell adhesion,-,K06787//Leukocyte transendothelial migration;Cell adhesion molecules (CAMs)
2203,0,0,0,14,1,0,0,3,0,0,44,0,"FBP1;fructose-1,6-bisphosphatase 1",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006006//glucose metabolic process;GO:0046580//negative regulation of Ras protein signal transduction;GO:0044281//small molecule metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0051289//protein homotetramerization;GO:0005975//carbohydrate metabolic process;GO:0030308//negative regulation of cell growth;GO:0045820//negative regulation of glycolytic process;GO:0071286//cellular response to magnesium ion;GO:0006000//fructose metabolic process;GO:0016311//dephosphorylation;GO:0035690//cellular response to drug;GO:0006094//gluconeogenesis,"GO:0016208//AMP binding;GO:0048029//monosaccharide binding;GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding",K03841//Metabolic pathways;Pentose phosphate pathway;Fructose and mannose metabolism;Insulin signaling pathway;Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Carbon fixation in photosynthetic organisms;Methane metabolism;Biosynthesis of secondary metabolites
220323,0,0,0,0,0,0,0,0,14,0,0,0,OAF;OAF homolog (Drosophila),GO:0070062//extracellular vesicular exosome,-,-,-
220359,98,0,0,0,0,0,12,0,0,0,2,1,TIGD3;tigger transposable element derived 3,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
220382,0,0,0,3,10,0,0,0,10,0,0,0,"FAM181B;family with sequence similarity 181, member B",-,-,-,-
220388,0,0,0,0,0,0,0,46,0,0,0,0,CCDC89;coiled-coil domain containing 89,GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);K09291//RNA transport;Thyroid cancer;MAPK signaling pathway - yeast;Pathways in cancer
2204,0,0,0,0,0,0,16,0,0,0,0,0,"FCAR;Fc fragment of IgA, receptor for",GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006955//immune response,GO:0019862//IgA binding,K06513//Phagosome;Staphylococcus aureus infection
220416,0,0,0,4,0,0,29,1,13,0,1,0,LRRC63;leucine rich repeat containing 63,-,-,-,K10130//p53 signaling pathway;NF-kappa B signaling pathway
220429,0,0,0,0,0,40,0,0,0,286,10,10,"CTAGE10P;CTAGE family, member 10, pseudogene",-,-,-,K06102//Tight junction
220441,0,0,0,8,12,0,11,0,18,0,0,0,RNF152;ring finger protein 152,GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0070936//protein K48-linked ubiquitination;GO:0006915//apoptotic process,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
2205,0,0,0,0,0,0,0,0,3,0,0,0,"FCER1A;Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide",GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0001812//positive regulation of type I hypersensitivity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007257//activation of JUN kinase activity;GO:0019370//leukotriene biosynthetic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0045425//positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0043306//positive regulation of mast cell degranulation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0045087//innate immune response;GO:0001820//serotonin secretion;GO:0045401//positive regulation of interleukin-3 biosynthetic process,GO:0019767//IgE receptor activity;GO:0019863//IgE binding,K08089//Asthma;Fc epsilon RI signaling pathway
220594,0,0,0,0,0,1,41,1,28,0,10,0,USP32P2;ubiquitin specific peptidase 32 pseudogene 2,-,-,-,-
2206,5,0,0,0,0,0,2,0,33,0,0,0,"MS4A2;membrane-spanning 4-domains, subfamily A, member 2",GO:0032998//Fc-epsilon receptor I complex;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane,GO:0045087//innate immune response;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0006954//inflammatory response;GO:0043306//positive regulation of mast cell degranulation;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0006955//immune response;GO:0050663//cytokine secretion;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007202//activation of phospholipase C activity,GO:0042169//SH2 domain binding;GO:0019901//protein kinase binding;GO:0051219//phosphoprotein binding;GO:0019863//IgE binding,K08090//Asthma;Fc epsilon RI signaling pathway
2207,0,0,0,0,0,0,0,0,0,0,10,0,"FCER1G;Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide",GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0032998//Fc-epsilon receptor I complex;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,"GO:0045576//mast cell activation;GO:0001798//positive regulation of type IIa hypersensitivity;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation;GO:0010543//regulation of platelet activation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0001812//positive regulation of type I hypersensitivity;GO:0032755//positive regulation of interleukin-6 production;GO:0043306//positive regulation of mast cell degranulation;GO:0030168//platelet activation;GO:0002283//neutrophil activation involved in immune response;GO:0050900//leukocyte migration;GO:0032765//positive regulation of mast cell cytokine production;GO:0007229//integrin-mediated signaling pathway;GO:0050766//positive regulation of phagocytosis;GO:0030593//neutrophil chemotaxis;GO:0032733//positive regulation of interleukin-10 production;GO:0072659//protein localization to plasma membrane;GO:0006911//phagocytosis, engulfment;GO:0002554//serotonin secretion by platelet;GO:0042742//defense response to bacterium;GO:0033026//negative regulation of mast cell apoptotic process;GO:0045087//innate immune response;GO:0001805//positive regulation of type III hypersensitivity;GO:0016064//immunoglobulin mediated immune response;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production",GO:0019864//IgG binding;GO:0005515//protein binding;GO:0019863//IgE binding;GO:0019767//IgE receptor activity,K07983//Fc epsilon RI signaling pathway;Natural killer cell mediated cytotoxicity;Asthma;Tuberculosis
2208,0,0,0,0,0,0,0,0,2,0,0,0,"FCER2;Fc fragment of IgE, low affinity II, receptor for (CD23)",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0051712//positive regulation of killing of cells of other organism;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0007219//Notch signaling pathway,GO:0019863//IgE binding;GO:0030246//carbohydrate binding;GO:0005178//integrin binding;GO:0046872//metal ion binding,K06468//Epstein-Barr virus infection;Hematopoietic cell lineage
220869,0,30,0,0,7,13,25,0,36,0,0,1,CBWD5;COBW domain containing 5,-,-,GO:0005524//ATP binding,-
2209,0,0,0,67,34,9,0,0,0,0,57,0,"FCGR1A;Fc fragment of IgG, high affinity Ia, receptor (CD64)",GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane,"GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0001805//positive regulation of type III hypersensitivity;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006910//phagocytosis, recognition;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0006955//immune response;GO:0006911//phagocytosis, engulfment;GO:0007165//signal transduction;GO:0050766//positive regulation of phagocytosis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0019221//cytokine-mediated signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0001798//positive regulation of type IIa hypersensitivity",GO:0019864//IgG binding;GO:0005057//receptor signaling protein activity;GO:0005515//protein binding;GO:0019770//IgG receptor activity,K06498//Hematopoietic cell lineage;Staphylococcus aureus infection;Systemic lupus erythematosus;Leishmaniasis;Osteoclast differentiation;Phagosome;Tuberculosis;Transcriptional misregulation in cancer;Fc gamma R-mediated phagocytosis
220929,0,0,0,0,0,13,103,0,25,0,0,0,ZNF438;zinc finger protein 438,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K09299//Transcriptional misregulation in cancer
220963,173,0,0,0,0,0,0,0,33,0,0,0,"SLC16A9;solute carrier family 16, member 9",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0046415//urate metabolic process,GO:0015293//symporter activity,-
220965,93,0,0,49,54,15,16,0,10,0,28,0,"FAM13C;family with sequence similarity 13, member C",-,-,-,-
220972,0,1,0,3,32,16,0,0,0,219,11,0,"MARCH8;membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase",GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0005768//endosome,GO:0000209//protein polyubiquitination;GO:0002376//immune system process,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
220979,0,0,0,0,0,10,18,0,0,0,0,0,C10orf25;chromosome 10 open reading frame 25,GO:0005576//extracellular region,-,-,-
220988,0,174,51,241,616,0,0,0,41,0,82,0,HNRNPA3;heterogeneous nuclear ribonucleoprotein A3,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030529//ribonucleoprotein complex;GO:0071013//catalytic step 2 spliceosome,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,K12741//Spliceosome
220992,1,0,0,0,0,0,0,58,0,0,0,0,ZNF485;zinc finger protein 485,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
221,0,0,0,0,19,0,0,59,19,0,9,0,"ALDH3B1;aldehyde dehydrogenase 3 family, member B1",GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0006066//alcohol metabolic process;GO:0034599//cellular response to oxidative stress;GO:0055114//oxidation-reduction process;GO:0006629//lipid metabolic process;GO:0046185//aldehyde catabolic process;GO:0006068//ethanol catabolic process,GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity,K00129//Microbial metabolism in diverse environments;Histidine metabolism;Glycolysis / Gluconeogenesis;Tyrosine metabolism;beta-Alanine metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Phenylalanine metabolism
2210,4,1,0,0,22,24,19,0,1,0,0,0,"FCGR1B;Fc fragment of IgG, high affinity Ib, receptor (CD64)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0030669//clathrin-coated endocytic vesicle membrane,"GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006955//immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0038093//Fc receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I",GO:0019864//IgG binding;GO:0019763//immunoglobulin receptor activity,K06498//Tuberculosis;Transcriptional misregulation in cancer;Fc gamma R-mediated phagocytosis;Phagosome;Osteoclast differentiation;Systemic lupus erythematosus;Leishmaniasis;Staphylococcus aureus infection;Hematopoietic cell lineage
221002,0,0,0,0,0,22,6,36,24,0,0,0,"RASGEF1A;RasGEF domain family, member 1A",GO:0005622//intracellular,GO:0032320//positive regulation of Ras GTPase activity;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0016477//cell migration,GO:0005088//Ras guanyl-nucleotide exchange factor activity,K07376//Gap junction;Vascular smooth muscle contraction;Long-term depression;Olfactory transduction;Salivary secretion;K08018//MAPK signaling pathway
221035,0,0,0,15,29,0,15,70,0,123,0,0,REEP3;receptor accessory protein 3,GO:0016021//integral component of membrane;GO:0005874//microtubule;GO:0005789//endoplasmic reticulum membrane,GO:0007067//mitotic nuclear division;GO:0007084//mitotic nuclear envelope reassembly;GO:0006998//nuclear envelope organization,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
221037,75,53,0,26,154,0,39,349,73,1,64,1,JMJD1C;jumonji domain containing 1C,GO:0005654//nucleoplasm;GO:0005622//intracellular,"GO:0006351//transcription, DNA-templated;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0051213//dioxygenase activity;GO:0046966//thyroid hormone receptor binding,K11449//Transcriptional misregulation in cancer
221060,0,0,0,9,31,0,0,1,0,0,17,0,C10orf111;chromosome 10 open reading frame 111,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
221061,0,0,0,0,0,0,0,0,30,0,0,0,"FAM171A1;family with sequence similarity 171, member A1",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
221074,71,0,0,0,0,0,0,0,32,0,0,0,"SLC39A12;solute carrier family 39 (zinc transporter), member 12",GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0071578//zinc ion transmembrane import;GO:0010975//regulation of neuron projection development;GO:0007165//signal transduction,GO:0005385//zinc ion transmembrane transporter activity,-
221078,0,0,0,0,0,0,0,43,25,0,0,0,"NSUN6;NOP2/Sun domain family, member 6",-,GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0003723//RNA binding,-
221079,0,0,16,0,9,0,0,28,3,0,0,1,ARL5B;ADP-ribosylation factor-like 5B,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
221091,0,0,0,0,0,0,0,0,44,0,0,0,LRRN4CL;LRRN4 C-terminal like,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
221092,0,37,0,13,87,3,0,0,0,0,0,0,HNRNPUL2;heterogeneous nuclear ribonucleoprotein U-like 2,GO:0016020//membrane;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,K12888//Spliceosome
221120,0,21,0,0,45,0,29,0,46,0,10,0,"ALKBH3;alkB, alkylation repair homolog 3 (E. coli)",GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0008283//cell proliferation;GO:0006281//DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0035552//oxidative single-stranded DNA demethylation,GO:0031418//L-ascorbic acid binding;GO:0008198//ferrous iron binding;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0005515//protein binding,-
221143,233,2,0,0,5,0,0,0,1,0,0,0,N6AMT2;N-6 adenine-specific DNA methyltransferase 2 (putative),GO:0070062//extracellular vesicular exosome,GO:0032259//methylation,GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity,-
221150,2,0,0,0,0,10,54,3,28,0,6,0,SKA3;spindle and kinetochore associated complex subunit 3,GO:0005737//cytoplasm;GO:0005876//spindle microtubule;GO:0000940//condensed chromosome outer kinetochore,GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0031110//regulation of microtubule polymerization or depolymerization,GO:0005515//protein binding,-
221154,0,1,0,9,40,0,0,0,33,0,0,0,MICU2;mitochondrial calcium uptake 2,GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:1990246//uniplex complex;GO:0034704//calcium channel complex,GO:0006851//mitochondrial calcium ion transport;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0051562//negative regulation of mitochondrial calcium ion concentration,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
221178,0,3,1,12,175,13,61,1,22,0,9,0,SPATA13;spermatogenesis associated 13,GO:0032587//ruffle membrane;GO:0030175//filopodium;GO:0005730//nucleolus;GO:0030027//lamellipodium;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0016477//cell migration;GO:0032855//positive regulation of Rac GTPase activity;GO:0046847//filopodium assembly;GO:0030334//regulation of cell migration;GO:0043547//positive regulation of GTPase activity;GO:0030032//lamellipodium assembly,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity,K05769//Regulation of actin cytoskeleton
221184,0,0,0,0,0,9,13,0,8,238,0,0,CPNE2;copine II,GO:0070062//extracellular vesicular exosome,-,-,K06491//Prion diseases;Cell adhesion molecules (CAMs);K15290//Synaptic vesicle cycle
221188,0,0,35,0,0,0,0,0,36,117,38,0,GPR114;G protein-coupled receptor 114,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
221191,0,132,55,131,151,0,14,1,55,150,233,0,"PRSS54;protease, serine, 54",GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01324//Complement and coagulation cascades;K01323//Complement and coagulation cascades
2212,0,0,0,0,0,2,0,0,0,0,0,0,"FCGR2A;Fc fragment of IgG, low affinity IIa, receptor (CD32)",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0045087//innate immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0019864//IgG binding,K06472//Fc gamma R-mediated phagocytosis;Tuberculosis;Phagosome;Staphylococcus aureus infection;Osteoclast differentiation;Systemic lupus erythematosus;Leishmaniasis
221223,0,0,0,0,0,0,33,0,13,0,7,0,CES5A;carboxylesterase 5A,GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
221262,0,0,0,0,0,0,0,0,11,0,0,0,"CCDC162P;coiled-coil domain containing 162, pseudogene",-,-,-,-
221264,0,15,0,11,3,48,12,7,41,0,10,0,AK9;adenylate kinase 9,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005730//nucleolus,GO:0006757//ADP phosphorylation;GO:0061568//GDP phosphorylation;GO:0061508//CDP phosphorylation;GO:0061570//dCDP phosphorylation;GO:0006186//dGDP phosphorylation;GO:0061571//TDP phosphorylation;GO:0061569//UDP phosphorylation;GO:0061567//dCMP phosphorylation;GO:0006756//AMP phosphorylation;GO:0061566//CMP phosphorylation;GO:0061565//dAMP phosphorylation;GO:0006174//dADP phosphorylation,GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0050145//nucleoside phosphate kinase activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
221294,108,17,0,27,101,0,0,44,28,0,0,0,NT5DC1;5'-nucleotidase domain containing 1,-,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K01081//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;Nicotinate and nicotinamide metabolism
2213,0,0,0,0,0,6,0,0,21,0,0,0,"FCGR2B;Fc fragment of IgG, low affinity IIb, receptor (CD32)",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0016032//viral process;GO:0006955//immune response;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0019864//IgG binding,K06472//Tuberculosis;Fc gamma R-mediated phagocytosis;Phagosome;Staphylococcus aureus infection;Leishmaniasis;Systemic lupus erythematosus;Osteoclast differentiation;K12560//Measles;Systemic lupus erythematosus;Osteoclast differentiation;Staphylococcus aureus infection;Tuberculosis;Fc gamma R-mediated phagocytosis;B cell receptor signaling pathway;Phagosome
221301,0,0,0,0,0,17,48,0,0,0,0,0,"FAM26D;family with sequence similarity 26, member D",GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
221302,0,0,0,9,0,0,0,0,15,0,0,0,ZUFSP;zinc finger with UFM1-specific peptidase domain,-,-,GO:0046872//metal ion binding,-
221303,0,0,0,0,0,0,0,0,12,0,0,0,"FAM162B;family with sequence similarity 162, member B",GO:0016021//integral component of membrane,-,-,-
221322,0,3,0,1,21,25,5,0,65,0,0,0,"TBC1D32;TBC1 domain family, member 32",GO:0005737//cytoplasm;GO:0005929//cilium,GO:0032851//positive regulation of Rab GTPase activity;GO:0002088//lens development in camera-type eye;GO:0060271//cilium morphogenesis;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0042733//embryonic digit morphogenesis;GO:0061512//protein localization to cilium;GO:0003406//retinal pigment epithelium development,GO:0005097//Rab GTPase activator activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
221336,56,0,0,0,0,0,0,0,2,0,5,0,BEND6;BEN domain containing 6,-,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0001106//RNA polymerase II transcription corepressor activity,-
221357,0,0,0,0,0,0,0,0,22,0,0,0,GSTA5;glutathione S-transferase alpha 5,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006749//glutathione metabolic process,GO:0004364//glutathione transferase activity,K00799//Glutathione metabolism;Prostate cancer;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
221391,0,0,0,0,0,29,21,72,47,0,0,0,OPN5;opsin 5,GO:0016021//integral component of membrane,GO:0007602//phototransduction;GO:0018298//protein-chromophore linkage;GO:0007601//visual perception;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0009881//photoreceptor activity,-
221393,0,0,0,0,0,0,0,0,2,0,0,0,GPR115;G protein-coupled receptor 115,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
221395,0,0,0,0,0,13,22,0,53,0,0,0,GPR116;G protein-coupled receptor 116,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0031410//cytoplasmic vesicle,GO:0019216//regulation of lipid metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045444//fat cell differentiation;GO:0043129//surfactant homeostasis;GO:0007218//neuropeptide signaling pathway;GO:0006112//energy reserve metabolic process;GO:0042593//glucose homeostasis,GO:0004930//G-protein coupled receptor activity,-
2214,0,0,0,0,0,1,0,0,0,0,6,0,"FCGR3A;Fc fragment of IgG, low affinity IIIa, receptor (CD16a)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0050776//regulation of immune response;GO:0006955//immune response;GO:0045087//innate immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0019864//IgG binding,K06463//Phagosome;Fc gamma R-mediated phagocytosis;Tuberculosis;Staphylococcus aureus infection;Leishmaniasis;Osteoclast differentiation;Systemic lupus erythematosus;Natural killer cell mediated cytotoxicity
221400,0,19,117,161,228,15,64,0,65,0,0,0,TDRD6;tudor domain containing 6,GO:0005737//cytoplasm;GO:0043186//P granule;GO:0005783//endoplasmic reticulum;GO:0033391//chromatoid body,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0007281//germ cell development,-,K15979//Epstein-Barr virus infection
221409,0,0,0,0,0,0,0,0,21,148,0,277,"SPATS1;spermatogenesis associated, serine-rich 1",-,-,-,-
221416,0,0,0,0,0,0,39,2,34,0,0,0,C6orf223;chromosome 6 open reading frame 223,-,-,-,-
221421,0,0,0,18,2,0,0,0,7,0,1,2,RSPH9;radial spoke head 9 homolog (Chlamydomonas),GO:0031514//motile cilium;GO:0005930//axoneme;GO:0005856//cytoskeleton,GO:0003341//cilium movement;GO:0035082//axoneme assembly,-,-
221424,0,0,0,0,0,0,0,0,11,0,10,0,LRRC73;leucine rich repeat containing 73,-,-,-,-
221442,0,0,0,0,0,24,42,59,34,0,0,0,ADCY10P1;adenylate cyclase 10 (soluble) pseudogene 1,-,-,-,K11265//Purine metabolism
221443,0,19,0,10,71,0,0,0,0,0,0,0,OARD1;O-acyl-ADP-ribose deacylase 1,-,GO:0042278//purine nucleoside metabolic process,GO:0001883//purine nucleoside binding;GO:0005515//protein binding;GO:0019213//deacetylase activity,-
221458,87,0,1,0,0,46,20,0,70,0,0,0,KIF6;kinesin family member 6,GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus,GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity,-
221468,0,0,0,16,57,0,4,0,0,0,0,0,TMEM217;transmembrane protein 217,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
221472,0,0,0,0,0,0,0,0,16,1,8,0,"FGD2;FYVE, RhoGEF and PH domain containing 2",GO:0005794//Golgi apparatus;GO:0001726//ruffle;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0031901//early endosome membrane;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0007264//small GTPase mediated signal transduction;GO:0043088//regulation of Cdc42 GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007010//cytoskeleton organization;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0031267//small GTPase binding,-
221476,0,0,0,0,1,18,0,12,52,0,26,0,PI16;peptidase inhibitor 16,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0010466//negative regulation of peptidase activity,GO:0030414//peptidase inhibitor activity,K00747//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;K02330//HTLV-I infection;Base excision repair
221477,0,129,44,95,245,22,10,48,100,0,102,1,C6orf89;chromosome 6 open reading frame 89,GO:0030496//midbody;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0050673//epithelial cell proliferation;GO:0042060//wound healing;GO:0045787//positive regulation of cell cycle,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
221481,147,0,0,0,0,0,15,0,30,0,13,0,ARMC12;armadillo repeat containing 12,GO:0005634//nucleus,-,-,-
221491,0,0,0,0,0,0,0,0,0,0,7,0,C6orf1;chromosome 6 open reading frame 1,GO:0005576//extracellular region,-,-,-
221496,0,0,0,0,0,0,24,0,28,0,7,0,LEMD2;LEM domain containing 2,GO:0031965//nuclear membrane;GO:0005639//integral component of nuclear inner membrane;GO:0016020//membrane,GO:0035914//skeletal muscle cell differentiation;GO:0043409//negative regulation of MAPK cascade,-,-
2215,0,0,0,0,0,16,0,0,33,0,1,0,"FCGR3B;Fc fragment of IgG, low affinity IIIb, receptor (CD16b)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031225//anchored component of membrane,GO:0006955//immune response,GO:0019864//IgG binding,K06463//Staphylococcus aureus infection;Natural killer cell mediated cytotoxicity;Leishmaniasis;Osteoclast differentiation;Systemic lupus erythematosus;Fc gamma R-mediated phagocytosis;Tuberculosis;Phagosome
221504,0,0,0,0,0,0,0,0,0,0,2,0,ZBTB9;zinc finger and BTB domain containing 9,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
221527,0,0,0,0,16,0,0,0,0,0,0,0,ZBTB12;zinc finger and BTB domain containing 12,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
221613,0,0,0,0,0,0,14,0,0,0,0,0,"HIST1H2AA;histone cluster 1, H2aa",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11251//Systemic lupus erythematosus;Alcoholism
221656,0,0,0,8,40,0,0,0,38,152,0,0,KDM1B;lysine (K)-specific demethylase 1B,GO:0005634//nucleus,"GO:0006349//regulation of gene expression by genetic imprinting;GO:0034720//histone H3-K4 demethylation;GO:0043046//DNA methylation involved in gamete generation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0044030//regulation of DNA methylation;GO:0055114//oxidation-reduction process;GO:0007275//multicellular organismal development",GO:0034649//histone demethylase activity (H3-monomethyl-K4 specific);GO:0050660//flavin adenine dinucleotide binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity;GO:0034648//histone demethylase activity (H3-dimethyl-K4 specific),-
221662,95,0,0,0,0,0,0,0,0,0,0,0,RBM24;RNA binding motif protein 24,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0043488//regulation of mRNA stability;GO:0010830//regulation of myotube differentiation,GO:0003730//mRNA 3'-UTR binding;GO:0000166//nucleotide binding,K12741//Spliceosome;K14411//mRNA surveillance pathway
221687,81,0,0,0,0,0,0,0,2,0,14,294,RNF182;ring finger protein 182,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
221692,0,0,0,0,0,0,10,0,17,0,16,0,PHACTR1;phosphatase and actin regulator 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse,GO:0031032//actomyosin structure organization;GO:0031532//actin cytoskeleton reorganization;GO:0048870//cell motility;GO:0043149//stress fiber assembly;GO:0043086//negative regulation of catalytic activity,GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity,-
2217,0,0,0,0,0,0,0,0,31,67,0,0,"FCGRT;Fc fragment of IgG, receptor, transporter, alpha",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0019882//antigen processing and presentation;GO:0006955//immune response;GO:0002416//IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor,GO:0019864//IgG binding;GO:0030881//beta-2-microglobulin binding,K06751//Epstein-Barr virus infection;Antigen processing and presentation;Allograft rejection;Herpes simplex infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Viral myocarditis;Graft-versus-host disease;Type I diabetes mellitus;HTLV-I infection;Endocytosis;Autoimmune thyroid disease;Phagosome
221710,0,0,0,10,65,0,5,0,0,0,0,0,SMIM13;small integral membrane protein 13,GO:0016021//integral component of membrane,-,-,-
221711,0,0,13,0,0,9,52,1,24,152,11,0,SYCP2L;synaptonemal complex protein 2-like,GO:0005634//nucleus,-,-,-
221749,0,0,0,1,1,0,8,0,0,0,15,0,PXDC1;PX domain containing 1,-,-,GO:0035091//phosphatidylinositol binding,-
221785,0,0,0,1,5,0,0,0,0,0,11,267,ZSCAN25;zinc finger and SCAN domain containing 25,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
221786,0,0,0,0,7,0,0,0,13,0,20,0,"FAM200A;family with sequence similarity 200, member A",GO:0016021//integral component of membrane,-,GO:0003676//nucleic acid binding,K06264//ECM-receptor interaction;K06103//Tight junction;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
2218,0,0,0,15,3,6,0,0,36,0,0,0,FKTN;fukutin,GO:0005634//nucleus;GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0007517//muscle organ development;GO:0008285//negative regulation of cell proliferation;GO:0046329//negative regulation of JNK cascade;GO:0007399//nervous system development;GO:0060049//regulation of protein glycosylation;GO:0008152//metabolic process,GO:0016740//transferase activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K11447//Transcriptional misregulation in cancer
221806,0,0,0,0,0,42,31,0,9,0,0,0,VWDE;von Willebrand factor D and EGF domains,GO:0005576//extracellular region,-,-,K01691//Wnt signaling pathway
221823,0,0,0,0,0,0,37,0,0,0,0,0,PRPS1L1;phosphoribosyl pyrophosphate synthetase 1-like 1,-,GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0016310//phosphorylation;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0009165//nucleotide biosynthetic process,GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0000287//magnesium ion binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0042803//protein homodimerization activity,K00948//Purine metabolism;Biosynthesis of secondary metabolites;Thiamine metabolism;Metabolic pathways;Pentose phosphate pathway;Oxidative phosphorylation;Microbial metabolism in diverse environments
221830,0,1,0,4,84,0,0,0,0,0,0,0,TWISTNB;TWIST neighbor,GO:0005730//nucleolus;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton,GO:0006360//transcription from RNA polymerase I promoter,GO:0001054//RNA polymerase I activity,K03004//Metabolic pathways;Pyrimidine metabolism;Purine metabolism;RNA polymerase
221833,0,0,0,7,17,9,0,0,10,0,4,0,SP8;Sp8 transcription factor,GO:0005634//nucleus,"GO:0030326//embryonic limb morphogenesis;GO:0009954//proximal/distal pattern formation;GO:0009953//dorsal/ventral pattern formation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
221895,0,26,51,56,37,0,2,0,21,0,45,0,JAZF1;JAZF zinc finger 1,GO:0017053//transcriptional repressor complex;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity;GO:0046872//metal ion binding,-
221908,0,0,0,26,8,0,0,1,0,0,1,0,"PPP1R35;protein phosphatase 1, regulatory subunit 35",-,GO:0010923//negative regulation of phosphatase activity,GO:0019902//phosphatase binding;GO:0004864//protein phosphatase inhibitor activity,-
221914,94,0,0,0,2,0,0,1,0,0,0,0,GPC2;glypican 2,GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen;GO:0031225//anchored component of membrane,"GO:0007224//smoothened signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0001523//retinoid metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030182//neuron differentiation;GO:0007603//phototransduction, visible light;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process",GO:0043395//heparan sulfate proteoglycan binding,-
221927,0,0,0,0,0,0,54,92,0,156,31,1,BRAT1;BRCA1-associated ATM activator 1,GO:0005634//nucleus;GO:0016020//membrane,GO:0010212//response to ionizing radiation,GO:0005515//protein binding,-
221935,0,0,0,0,6,21,27,105,155,95,27,656,SDK1;sidekick cell adhesion molecule 1,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,K06252//ECM-receptor interaction;Focal adhesion
221937,3,11,0,13,7,3,0,78,34,0,16,67,FOXK1;forkhead box K1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0030308//negative regulation of cell growth;GO:0007517//muscle organ development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
221938,8,0,0,0,0,0,19,0,25,0,2,0,MMD2;monocyte to macrophage differentiation-associated 2,GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,-,-,-
221955,0,0,0,0,0,8,31,0,12,0,22,0,"DAGLB;diacylglycerol lipase, beta",GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007405//neuroblast proliferation;GO:0019369//arachidonic acid metabolic process;GO:0007596//blood coagulation;GO:0016042//lipid catabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0030168//platelet activation,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K13806//Retrograde endocannabinoid signaling;Phototransduction - fly
221960,0,0,0,0,14,20,0,0,0,0,9,0,CCZ1B;CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae),GO:0005765//lysosomal membrane,-,-,K08269//Regulation of autophagy;mTOR signaling pathway
221981,4,0,0,0,0,70,0,0,41,0,16,0,"THSD7A;thrombospondin, type I, domain containing 7A",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030154//cell differentiation;GO:0001525//angiogenesis,-,-
222,0,0,1,0,4,15,0,0,55,0,7,0,"ALDH3B2;aldehyde dehydrogenase 3 family, member B2",-,GO:0006068//ethanol catabolic process;GO:0006066//alcohol metabolic process;GO:0055114//oxidation-reduction process;GO:0006629//lipid metabolic process,GO:0004028//3-chloroallyl aldehyde dehydrogenase activity;GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity,K00129//Metabolism of xenobiotics by cytochrome P450;Phenylalanine metabolism;Tyrosine metabolism;Drug metabolism - cytochrome P450;beta-Alanine metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Histidine metabolism;Microbial metabolism in diverse environments
2220,0,0,0,0,0,0,0,0,11,0,0,0,FCN2;ficolin (collagen/fibrinogen domain containing lectin) 2,GO:0005581//collagen trimer;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0045087//innate immune response;GO:0006956//complement activation;GO:0008228//opsonization;GO:0001867//complement activation, lectin pathway",GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0003823//antigen binding;GO:0005515//protein binding;GO:0030246//carbohydrate binding,-
222068,0,0,0,7,12,0,0,0,15,0,0,0,TMED4;transmembrane emp24 protein transport domain containing 4,GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0004871//signal transducer activity,-
222161,0,0,0,11,1,0,25,0,47,0,0,0,DKFZP586I1420;uncharacterized protein DKFZp586I1420,-,-,-,K03066//Proteasome;Epstein-Barr virus infection
222166,0,33,1,60,221,46,17,1,39,0,14,0,"MTURN;maturin, neural progenitor differentiation regulator homolog (Xenopus)",-,GO:0007275//multicellular organismal development,-,-
222171,0,0,0,0,0,0,0,0,3,0,0,0,PRR15;proline rich 15,-,GO:0007275//multicellular organismal development,-,-
222183,95,0,0,0,0,0,56,0,54,0,0,0,SRRM3;serine/arginine repetitive matrix 3,-,-,-,-
222194,0,0,0,25,15,15,26,0,28,0,5,0,RSBN1L;round spermatid basic protein 1-like,GO:0005634//nucleus,-,-,-
2222,78,235,0,48,271,9,0,45,9,0,30,0,FDFT1;farnesyl-diphosphate farnesyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0044255//cellular lipid metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006694//steroid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0016491//oxidoreductase activity;GO:0004310//farnesyl-diphosphate farnesyltransferase activity;GO:0051996//squalene synthase activity,K00801//Metabolic pathways;Sesquiterpenoid and triterpenoid biosynthesis;Biosynthesis of secondary metabolites
222223,90,0,0,8,20,30,0,0,170,123,5,0,KIAA1324L;KIAA1324-like,GO:0016021//integral component of membrane,-,-,-
222229,0,41,0,0,0,0,0,46,0,0,15,0,LRWD1;leucine-rich repeats and WD repeat domain containing 1,GO:0031933//telomeric heterochromatin;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005721//pericentric heterochromatin;GO:0005664//nuclear origin of replication recognition complex,GO:0006325//chromatin organization;GO:0016568//chromatin modification;GO:0006270//DNA replication initiation;GO:0071169//establishment of protein localization to chromatin,GO:0003682//chromatin binding;GO:0035064//methylated histone binding;GO:0008327//methyl-CpG binding;GO:0005515//protein binding,K13131//RNA transport
222234,0,42,0,0,0,27,0,0,0,0,12,0,"FAM185A;family with sequence similarity 185, member A",-,-,-,-
222235,139,0,0,19,0,11,1,0,70,0,25,1,FBXL13;F-box and leucine-rich repeat protein 13,-,-,-,-
222236,0,79,84,185,449,0,0,0,102,0,135,0,NAPEPLD;N-acyl phosphatidylethanolamine phospholipase D,GO:0042622//photoreceptor outer segment membrane;GO:0070062//extracellular vesicular exosome,GO:0009395//phospholipid catabolic process,GO:0008270//zinc ion binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity,K13985//Retrograde endocannabinoid signaling
222255,0,0,0,0,36,15,10,1,67,14,0,0,ATXN7L1;ataxin 7-like 1,-,-,-,-
222389,0,0,0,5,0,0,0,0,0,0,2,0,BEND7;BEN domain containing 7,GO:0070062//extracellular vesicular exosome,-,GO:0005515//protein binding,-
2224,0,33,2,66,66,15,0,10,24,0,0,0,FDPS;farnesyl diphosphate synthase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0045337//farnesyl diphosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0016032//viral process;GO:0033384//geranyl diphosphate biosynthetic process,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0004337//geranyltranstransferase activity;GO:0004161//dimethylallyltranstransferase activity,K00787//HTLV-I infection;Metabolic pathways;Terpenoid backbone biosynthesis;Influenza A;Biosynthesis of secondary metabolites
222484,37,0,0,15,48,0,70,0,74,0,0,0,LNX2;ligand of numb-protein X 2,-,GO:0051260//protein homooligomerization,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding,-
222487,24,0,0,0,0,12,28,0,15,0,0,0,GPR97;G protein-coupled receptor 97,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
222537,0,0,0,0,0,0,0,0,26,0,0,0,HS3ST5;heparan sulfate (glucosamine) 3-O-sulfotransferase 5,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,"GO:0005975//carbohydrate metabolic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0046596//regulation of viral entry into host cell;GO:0006477//protein sulfation;GO:0050819//negative regulation of coagulation",GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0005515//protein binding,K08104//Glycosaminoglycan biosynthesis - heparan sulfate
222545,0,0,0,0,0,0,55,0,9,0,6,0,"GPRC6A;G protein-coupled receptor, class C, group 6, member A",GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0043200//response to amino acid,GO:0004930//G-protein coupled receptor activity,-
222546,7,0,0,0,1,0,0,0,21,0,0,0,"RFX6;regulatory factor X, 6",GO:0005634//nucleus,"GO:0042593//glucose homeostasis;GO:0031018//endocrine pancreas development;GO:0003311//pancreatic D cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0003309//type B pancreatic cell differentiation;GO:0050796//regulation of insulin secretion;GO:0003310//pancreatic A cell differentiation;GO:0006351//transcription, DNA-templated;GO:0090104//pancreatic epsilon cell differentiation",GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding,-
222553,0,0,0,0,0,37,3,0,39,206,0,0,"SLC35F1;solute carrier family 35, member F1",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
222584,0,1,0,12,13,72,0,0,28,0,8,0,"FAM83B;family with sequence similarity 83, member B",-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
222611,0,0,36,0,0,47,21,0,45,0,3,0,GPR111;G protein-coupled receptor 111,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
222642,0,0,0,2,0,4,0,0,17,0,0,0,TSPO2;translocator protein 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0006810//transport,GO:0015485//cholesterol binding,K05770//Neuroactive ligand-receptor interaction;HTLV-I infection
222643,0,0,0,0,0,19,13,0,48,0,8,0,UNC5CL;unc-5 homolog C (C. elegans)-like,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0046330//positive regulation of JNK cascade;GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0008233//peptidase activity,K07521//Axon guidance
222658,0,1,1,56,158,0,0,49,41,266,7,0,KCTD20;potassium channel tetramerization domain containing 20,-,GO:0051260//protein homooligomerization,-,-
222659,0,0,0,0,0,0,27,16,0,0,0,0,"PXT1;peroxisomal, testis specific 1",GO:0005777//peroxisome;GO:0005634//nucleus,GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process,-,K03211//Dorso-ventral axis formation;Transcriptional misregulation in cancer;MAPK signaling pathway - fly
222662,0,0,0,0,0,5,0,0,2,0,0,0,LHFPL5;lipoma HMGIC fusion partner-like 5,GO:0016324//apical plasma membrane;GO:0032426//stereocilium bundle tip;GO:0016021//integral component of membrane,GO:0060088//auditory receptor cell stereocilium organization;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0006811//ion transport,-,-
222663,56,0,0,13,0,35,0,0,20,0,1,0,"SCUBE3;signal peptide, CUB domain, EGF-like 3",GO:0005576//extracellular region;GO:0009986//cell surface,GO:0051260//protein homooligomerization;GO:0051291//protein heterooligomerization,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
222696,0,0,0,0,1,3,0,0,35,0,0,0,ZSCAN23;zinc finger and SCAN domain containing 23,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
222698,0,0,0,0,0,0,29,0,0,0,0,0,NKAPL;NFKB activating protein-like,-,-,-,-
222699,0,0,0,0,0,16,33,30,14,64,8,0,"TOB2P1;transducer of ERBB2, 2 pseudogene 1",-,-,-,K14443//RNA degradation
222826,0,0,0,0,13,11,0,0,13,0,0,1,"FAM217A;family with sequence similarity 217, member A",-,-,-,-
222865,0,0,0,0,0,0,0,142,102,0,0,0,TMEM130;transmembrane protein 130,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways
222894,0,0,0,0,0,0,0,0,17,0,0,0,FERD3L;Fer3-like bHLH transcription factor,GO:0005634//nucleus,"GO:0048468//cell development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0033504//floor plate development;GO:0050767//regulation of neurogenesis",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
222950,0,0,0,0,0,14,0,6,11,0,0,0,NYAP1;neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1,-,GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0048812//neuron projection morphogenesis,-,-
222962,0,0,0,0,0,0,0,0,23,0,0,0,"SLC29A4;solute carrier family 29 (equilibrative nucleoside transporter), member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:1901642//nucleoside transmembrane transport;GO:0055085//transmembrane transport,GO:0005337//nucleoside transmembrane transporter activity,-
223,0,55,3,90,254,0,0,0,29,3,4,0,"ALDH9A1;aldehyde dehydrogenase 9 family, member A1",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0034641//cellular nitrogen compound metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0045329//carnitine biosynthetic process;GO:0055114//oxidation-reduction process;GO:0001889//liver development;GO:0044281//small molecule metabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0001822//kidney development;GO:0042445//hormone metabolic process,GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0042803//protein homodimerization activity;GO:0047105//4-trimethylammoniobutyraldehyde dehydrogenase activity;GO:0019145//aminobutyraldehyde dehydrogenase activity;GO:0033737//1-pyrroline dehydrogenase activity;GO:0051287//NAD binding;GO:0043176//amine binding;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity,"K00149//Metabolic pathways;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Propanoate metabolism;Pyruvate metabolism;Glycerolipid metabolism;Fatty acid metabolism;Lysine degradation;Arginine and proline metabolism;Histidine metabolism;Ascorbate and aldarate metabolism;Tryptophan metabolism;Glycolysis / Gluconeogenesis"
2230,0,0,0,1,29,0,0,0,41,0,2,0,FDX1;ferredoxin 1,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0008203//cholesterol metabolic process;GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0042446//hormone biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0005506//iron ion binding;GO:0009055//electron carrier activity",K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
223075,0,0,0,0,0,0,0,70,50,0,0,0,CCDC129;coiled-coil domain containing 129,-,-,GO:0005102//receptor binding,K08067//Long-term depression
223082,0,0,0,0,9,0,52,0,51,0,9,0,ZNRF2;zinc and ring finger 2,GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0030054//cell junction;GO:0010008//endosome membrane;GO:0030659//cytoplasmic vesicle membrane,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
223117,0,0,0,8,15,60,0,0,52,165,0,0,"SEMA3D;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D",GO:0005576//extracellular region;GO:0016020//membrane,GO:0007399//nervous system development;GO:0030154//cell differentiation,GO:0004872//receptor activity,K06840//Axon guidance
2232,3,0,0,0,0,12,18,0,2,0,0,0,FDXR;ferredoxin reductase,GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0006091//generation of precursor metabolites and energy;GO:0006694//steroid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008203//cholesterol metabolic process;GO:0070995//NADPH oxidation,GO:0004324//ferredoxin-NADP+ reductase activity;GO:0005515//protein binding;GO:0070402//NADPH binding;GO:0015039//NADPH-adrenodoxin reductase activity,-
2235,0,116,1,12,156,21,32,0,70,0,0,0,FECH;ferrochelatase,GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0006091//generation of precursor metabolites and energy;GO:0006783//heme biosynthetic process;GO:0010288//response to lead ion;GO:0046685//response to arsenic-containing substance;GO:0055072//iron ion homeostasis;GO:0008203//cholesterol metabolic process;GO:0045471//response to ethanol;GO:0030218//erythrocyte differentiation;GO:0042493//response to drug;GO:0010999//regulation of eIF2 alpha phosphorylation by heme;GO:0034379//very-low-density lipoprotein particle assembly;GO:0009589//detection of UV;GO:0044281//small molecule metabolic process;GO:0010468//regulation of gene expression;GO:0006778//porphyrin-containing compound metabolic process;GO:0071549//cellular response to dexamethasone stimulus;GO:0046501//protoporphyrinogen IX metabolic process;GO:0046984//regulation of hemoglobin biosynthetic process;GO:0070541//response to platinum ion;GO:0009416//response to light stimulus;GO:0051597//response to methylmercury;GO:0017085//response to insecticide,"GO:0005515//protein binding;GO:0004325//ferrochelatase activity;GO:0030350//iron-responsive element binding;GO:0008198//ferrous iron binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0020037//heme binding",K01772//Metabolic pathways;Porphyrin and chlorophyll metabolism;Biosynthesis of secondary metabolites
2237,0,0,0,8,1,0,0,0,9,0,0,0,FEN1;flap structure-specific endonuclease 1,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0000722//telomere maintenance via recombination;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000723//telomere maintenance;GO:0000738//DNA catabolic process, exonucleolytic;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair;GO:0007613//memory;GO:0006302//double-strand break repair;GO:0043137//DNA replication, removal of RNA primer;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006284//base-excision repair;GO:0009650//UV protection",GO:0005515//protein binding;GO:0004519//endonuclease activity;GO:0017108//5'-flap endonuclease activity;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0000287//magnesium ion binding;GO:0030145//manganese ion binding;GO:0003677//DNA binding;GO:0004527//exonuclease activity;GO:0008309//double-stranded DNA exodeoxyribonuclease activity;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0008409//5'-3' exonuclease activity,K04799//Base excision repair;Non-homologous end-joining;DNA replication
2239,108,0,0,0,0,31,0,0,15,1,0,0,GPC4;glypican 4,GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen,"GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0001523//retinoid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0007603//phototransduction, visible light;GO:0008283//cell proliferation",GO:0043395//heparan sulfate proteoglycan binding,K08110//Wnt signaling pathway
224,0,36,0,66,93,12,4,0,0,0,0,0,"ALDH3A2;aldehyde dehydrogenase 3 family, member A2",GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane;GO:0005777//peroxisome,GO:0055114//oxidation-reduction process;GO:0007422//peripheral nervous system development;GO:0006081//cellular aldehyde metabolic process;GO:0008544//epidermis development;GO:0033306//phytol metabolic process;GO:0007417//central nervous system development;GO:0006714//sesquiterpenoid metabolic process,GO:0004030//aldehyde dehydrogenase [NAD(P)+] activity;GO:0046577//long-chain-alcohol oxidase activity;GO:0050061//long-chain-aldehyde dehydrogenase activity;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0052814//medium-chain-aldehyde dehydrogenase activity,"K00128//Glycerolipid metabolism;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Limonene and pinene degradation;Bacterial chemotaxis;Glycolysis / Gluconeogenesis;Two-component system;Propanoate metabolism;Pyruvate metabolism;Pentose and glucuronate interconversions;Metabolic pathways;Arginine and proline metabolism;Lysine degradation;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Ascorbate and aldarate metabolism;Histidine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Tryptophan metabolism"
2241,123,0,52,7,56,32,0,0,49,0,1,0,FER;fer (fps/fes related) tyrosine kinase,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0030054//cell junction;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0000278//mitotic cell cycle;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0033007//negative regulation of mast cell activation involved in immune response;GO:0038109//Kit signaling pathway;GO:0070102//interleukin-6-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0030838//positive regulation of actin filament polymerization;GO:0001932//regulation of protein phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0032496//response to lipopolysaccharide;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034614//cellular response to reactive oxygen species;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0010762//regulation of fibroblast migration;GO:0036119//response to platelet-derived growth factor;GO:0000226//microtubule cytoskeleton organization;GO:0006935//chemotaxis;GO:0044331//cell-cell adhesion mediated by cadherin;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050904//diapedesis;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0032869//cellular response to insulin stimulus;GO:0008283//cell proliferation;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0008284//positive regulation of cell proliferation;GO:0035426//extracellular matrix-cell signaling;GO:0010591//regulation of lamellipodium assembly,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0045295//gamma-catenin binding;GO:0005524//ATP binding;GO:0017137//Rab GTPase binding;GO:0003779//actin binding;GO:0008289//lipid binding;GO:0045296//cadherin binding;GO:0019901//protein kinase binding;GO:0008157//protein phosphatase 1 binding;GO:0004713//protein tyrosine kinase activity;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding,K08889//Adherens junction
2242,109,57,0,0,0,15,26,0,34,0,26,0,"FES;FES proto-oncogene, tyrosine kinase",GO:0015630//microtubule cytoskeleton;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0005794//Golgi apparatus;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0045639//positive regulation of myeloid cell differentiation;GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0045595//regulation of cell differentiation;GO:0030155//regulation of cell adhesion;GO:0043304//regulation of mast cell degranulation;GO:2000145//regulation of cell motility;GO:0046777//protein autophosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0042127//regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0008283//cell proliferation;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0031116//positive regulation of microtubule polymerization;GO:0060627//regulation of vesicle-mediated transport,GO:0005524//ATP binding;GO:0034987//immunoglobulin receptor binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K07527//Axon guidance
2243,0,0,0,0,0,0,39,0,11,41,3,107,FGA;fibrinogen alpha chain,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0031982//vesicle;GO:0005938//cell cortex;GO:0005577//fibrinogen complex;GO:0031091//platelet alpha granule;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space,"GO:2000261//negative regulation of blood coagulation, common pathway;GO:0030198//extracellular matrix organization;GO:0070527//platelet aggregation;GO:0090277//positive regulation of peptide hormone secretion;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0051258//protein polymerization;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0043623//cellular protein complex assembly;GO:0050714//positive regulation of protein secretion;GO:0051592//response to calcium ion;GO:0045907//positive regulation of vasoconstriction;GO:0045921//positive regulation of exocytosis;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0007160//cell-matrix adhesion;GO:0070374//positive regulation of ERK1 and ERK2 cascade","GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0005102//receptor binding",K03903//Complement and coagulation cascades
2244,0,0,0,0,0,2,0,0,14,0,0,0,FGB;fibrinogen beta chain,GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0031091//platelet alpha granule;GO:0009986//cell surface;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005577//fibrinogen complex;GO:0005938//cell cortex;GO:0031982//vesicle,GO:0002576//platelet degranulation;GO:0051592//response to calcium ion;GO:0045907//positive regulation of vasoconstriction;GO:0045921//positive regulation of exocytosis;GO:0071347//cellular response to interleukin-1;GO:0007160//cell-matrix adhesion;GO:0044320//cellular response to leptin stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007596//blood coagulation;GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0043623//cellular protein complex assembly;GO:0050714//positive regulation of protein secretion;GO:0090277//positive regulation of peptide hormone secretion;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0070527//platelet aggregation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0051258//protein polymerization;GO:0030198//extracellular matrix organization,"GO:0005102//receptor binding;GO:0051087//chaperone binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding",K03904//Complement and coagulation cascades
2245,39,150,143,193,444,41,3,89,172,0,458,0,"FGD1;FYVE, RhoGEF and PH domain containing 1",GO:0001726//ruffle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0030036//actin cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0009887//organ morphogenesis;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:0007010//cytoskeleton organization;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043088//regulation of Cdc42 GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0046847//filopodium assembly;GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0031267//small GTPase binding;GO:0005085//guanyl-nucleotide exchange factor activity,K05720//Regulation of actin cytoskeleton
2246,0,0,0,0,0,0,0,0,35,0,0,0,FGF1;fibroblast growth factor 1 (acidic),GO:0005730//nucleolus;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005938//cell cortex;GO:0005634//nucleus,GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001525//angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0034605//cellular response to heat;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0030335//positive regulation of cell migration;GO:0048015//phosphatidylinositol-mediated signaling;GO:0009653//anatomical structure morphogenesis;GO:0072163//mesonephric epithelium development;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0007165//signal transduction;GO:0060681//branch elongation involved in ureteric bud branching;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051781//positive regulation of cell division;GO:0030154//cell differentiation;GO:1902533//positive regulation of intracellular signal transduction;GO:0007275//multicellular organismal development;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway,GO:0044548//S100 protein binding;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0008083//growth factor activity,K04358//Regulation of actin cytoskeleton;Melanoma;Pathways in cancer;MAPK signaling pathway
2247,19,0,56,30,24,1,21,4,20,0,7,0,FGF2;fibroblast growth factor 2 (basic),GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0042660//positive regulation of cell fate specification;GO:0007165//signal transduction;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045765//regulation of angiogenesis;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0048598//embryonic morphogenesis;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0007399//nervous system development;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045766//positive regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0061045//negative regulation of wound healing;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0060591//chondroblast differentiation;GO:0000187//activation of MAPK activity;GO:0042060//wound healing;GO:0030214//hyaluronan catabolic process;GO:0010863//positive regulation of phospholipase C activity;GO:0051781//positive regulation of cell division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0060548//negative regulation of cell death;GO:0010764//negative regulation of fibroblast migration;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006935//chemotaxis;GO:0032958//inositol phosphate biosynthetic process;GO:0007265//Ras protein signal transduction;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0050918//positive chemotaxis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0009887//organ morphogenesis;GO:0051209//release of sequestered calcium ion into cytosol",GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K04358//Pathways in cancer;MAPK signaling pathway;Melanoma;Regulation of actin cytoskeleton
2248,0,0,0,0,0,0,21,0,20,0,0,0,FGF3;fibroblast growth factor 3,GO:0005794//Golgi apparatus;GO:0005576//extracellular region,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048538//thymus development;GO:0030916//otic vesicle formation;GO:0007267//cell-cell signaling;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001759//organ induction;GO:0048752//semicircular canal morphogenesis;GO:0036342//post-anal tail morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0055026//negative regulation of cardiac muscle tissue development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051781//positive regulation of cell division;GO:0007165//signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway,GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity,K04358//Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Melanoma
225,0,0,0,0,0,0,15,0,24,0,0,0,"ABCD2;ATP-binding cassette, sub-family D (ALD), member 2",GO:0005777//peroxisome;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005778//peroxisomal membrane,GO:0006635//fatty acid beta-oxidation;GO:0042760//very long-chain fatty acid catabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0006200//ATP catabolic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0055085//transmembrane transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding",K05676//Peroxisome;ABC transporters
2250,0,0,0,0,0,36,0,1,31,0,0,0,FGF5;fibroblast growth factor 5,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0045087//innate immune response;GO:0051781//positive regulation of cell division;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010001//glial cell differentiation;GO:0008283//cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0007399//nervous system development,GO:0008083//growth factor activity;GO:0005104//fibroblast growth factor receptor binding,K04358//Melanoma;Regulation of actin cytoskeleton;MAPK signaling pathway;Pathways in cancer
2251,116,0,0,0,0,0,0,0,0,0,8,0,FGF6;fibroblast growth factor 6,GO:0005615//extracellular space;GO:0042383//sarcolemma;GO:0005576//extracellular region,GO:0045445//myoblast differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051781//positive regulation of cell division;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0001502//cartilage condensation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008283//cell proliferation,GO:0008083//growth factor activity;GO:0005104//fibroblast growth factor receptor binding,K04358//Regulation of actin cytoskeleton;Melanoma;MAPK signaling pathway;Pathways in cancer
2252,0,0,0,0,0,27,0,0,22,0,0,0,FGF7;fibroblast growth factor 7,GO:0005794//Golgi apparatus;GO:0005576//extracellular region,GO:0031532//actin cytoskeleton reorganization;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060445//branching involved in salivary gland morphogenesis;GO:0008544//epidermis development;GO:0034394//protein localization to cell surface;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0045087//innate immune response;GO:0050918//positive chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0010463//mesenchymal cell proliferation;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0051549//positive regulation of keratinocyte migration;GO:0061033//secretion by lung epithelial cell involved in lung growth;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0009611//response to wounding;GO:0007165//signal transduction;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010838//positive regulation of keratinocyte proliferation;GO:0051781//positive regulation of cell division,GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity,K04358//Melanoma;Regulation of actin cytoskeleton;Pathways in cancer;MAPK signaling pathway
2253,0,0,0,0,0,0,0,0,14,0,0,0,FGF8;fibroblast growth factor 8 (androgen-induced),GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region,GO:0051781//positive regulation of cell division;GO:0043524//negative regulation of neuron apoptotic process;GO:0014070//response to organic cyclic compound;GO:0035909//aorta morphogenesis;GO:0007369//gastrulation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001569//patterning of blood vessels;GO:0048853//forebrain morphogenesis;GO:0008406//gonad development;GO:0030917//midbrain-hindbrain boundary development;GO:0045840//positive regulation of mitosis;GO:0008286//insulin receptor signaling pathway;GO:0006979//response to oxidative stress;GO:0045087//innate immune response;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0050918//positive chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0021884//forebrain neuron development;GO:0035116//embryonic hindlimb morphogenesis;GO:0001759//organ induction;GO:0060425//lung morphogenesis;GO:0071542//dopaminergic neuron differentiation;GO:0030539//male genitalia development;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021846//cell proliferation in forebrain;GO:0008045//motor neuron axon guidance;GO:0001823//mesonephros development;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0046622//positive regulation of organ growth;GO:0048015//phosphatidylinositol-mediated signaling;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0030878//thyroid gland development;GO:0042476//odontogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0055026//negative regulation of cardiac muscle tissue development;GO:0033563//dorsal/ventral axon guidance;GO:0090134//cell migration involved in mesendoderm migration;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006915//apoptotic process;GO:0001839//neural plate morphogenesis;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060348//bone development;GO:0060037//pharyngeal system development;GO:0042493//response to drug;GO:0030916//otic vesicle formation;GO:0060563//neuroepithelial cell differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0001974//blood vessel remodeling;GO:0001656//metanephros development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001947//heart looping;GO:0021543//pallium development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0009653//anatomical structure morphogenesis;GO:0000165//MAPK cascade;GO:0021544//subpallium development;GO:0008078//mesodermal cell migration;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0023019//signal transduction involved in regulation of gene expression,GO:0005104//fibroblast growth factor receptor binding;GO:0042056//chemoattractant activity;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008083//growth factor activity;GO:0005105//type 1 fibroblast growth factor receptor binding,K04358//Regulation of actin cytoskeleton;Melanoma;MAPK signaling pathway;Pathways in cancer
2254,90,0,0,0,0,12,0,0,34,3,21,0,FGF9;fibroblast growth factor 9,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005604//basement membrane;GO:0005615//extracellular space,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0060484//lung-associated mesenchyme development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030238//male sex determination;GO:0002062//chondrocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0021762//substantia nigra development;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0048566//embryonic digestive tract development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0048505//regulation of timing of cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045087//innate immune response;GO:0042472//inner ear morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0001525//angiogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0010628//positive regulation of gene expression;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048706//embryonic skeletal system development;GO:0001649//osteoblast differentiation;GO:0051781//positive regulation of cell division;GO:0006606//protein import into nucleus;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0008584//male gonad development;GO:0008286//insulin receptor signaling pathway,GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0005104//fibroblast growth factor receptor binding,K04358//Melanoma;Regulation of actin cytoskeleton;MAPK signaling pathway;Pathways in cancer
2255,3,0,0,0,0,0,0,0,14,0,0,0,FGF10;fibroblast growth factor 10,GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0031012//extracellular matrix,"GO:0010634//positive regulation of epithelial cell migration;GO:0010631//epithelial cell migration;GO:0045747//positive regulation of Notch signaling pathway;GO:0070075//tear secretion;GO:0030878//thyroid gland development;GO:0042246//tissue regeneration;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0050872//white fat cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0043616//keratinocyte proliferation;GO:0060447//bud outgrowth involved in lung branching;GO:0060174//limb bud formation;GO:0071157//negative regulation of cell cycle arrest;GO:0046877//regulation of saliva secretion;GO:0031532//actin cytoskeleton reorganization;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0060595//fibroblast growth factor receptor signaling pathway involved in mammary gland specification;GO:0060449//bud elongation involved in lung branching;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0060496//mesenchymal-epithelial cell signaling involved in lung development;GO:0071338//positive regulation of hair follicle cell proliferation;GO:0048557//embryonic digestive tract morphogenesis;GO:0001974//blood vessel remodeling;GO:0001656//metanephros development;GO:0060436//bronchiole morphogenesis;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0030538//embryonic genitalia morphogenesis;GO:0008286//insulin receptor signaling pathway;GO:0070384//Harderian gland development;GO:0050671//positive regulation of lymphocyte proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0060915//mesenchymal cell differentiation involved in lung development;GO:0032355//response to estradiol;GO:0051145//smooth muscle cell differentiation;GO:0060615//mammary gland bud formation;GO:0050930//induction of positive chemotaxis;GO:0034394//protein localization to cell surface;GO:0032925//regulation of activin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008285//negative regulation of cell proliferation;GO:0060667//branch elongation involved in salivary gland morphogenesis;GO:0046579//positive regulation of Ras protein signal transduction;GO:0003338//metanephros morphogenesis;GO:0050673//epithelial cell proliferation;GO:0048536//spleen development;GO:0061115//lung proximal/distal axis specification;GO:0001759//organ induction;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0045740//positive regulation of DNA replication;GO:0000132//establishment of mitotic spindle orientation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070371//ERK1 and ERK2 cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0031076//embryonic camera-type eye development;GO:0048808//male genitalia morphogenesis;GO:0007431//salivary gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061033//secretion by lung epithelial cell involved in lung growth;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0060428//lung epithelium development;GO:0045739//positive regulation of DNA repair;GO:0042693//muscle cell fate commitment;GO:0060661//submandibular salivary gland formation;GO:0048807//female genitalia morphogenesis;GO:0000187//activation of MAPK activity;GO:0042060//wound healing;GO:0009880//embryonic pattern specification;GO:0008589//regulation of smoothened signaling pathway;GO:0060879//semicircular canal fusion;GO:0031016//pancreas development;GO:0050677//positive regulation of urothelial cell proliferation;GO:0030916//otic vesicle formation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0021983//pituitary gland development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051549//positive regulation of keratinocyte migration;GO:0042475//odontogenesis of dentin-containing tooth;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0060019//radial glial cell differentiation;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0035019//somatic stem cell maintenance;GO:0060513//prostatic bud formation;GO:0007368//determination of left/right symmetry;GO:0001823//mesonephros development;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0048754//branching morphogenesis of an epithelial tube;GO:0070352//positive regulation of white fat cell proliferation;GO:0032808//lacrimal gland development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0045087//innate immune response;GO:0060430//lung saccule development;GO:0060510//Type II pneumocyte differentiation;GO:0032781//positive regulation of ATPase activity;GO:0050918//positive chemotaxis;GO:0045931//positive regulation of mitotic cell cycle;GO:0043410//positive regulation of MAPK cascade;GO:0001525//angiogenesis",GO:0008083//growth factor activity;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008201//heparin binding;GO:0042056//chemoattractant activity;GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding,K04358//Regulation of actin cytoskeleton;Melanoma;MAPK signaling pathway;Pathways in cancer
2256,1,0,0,0,0,6,0,0,34,0,0,0,FGF11;fibroblast growth factor 11,GO:0005576//extracellular region,GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0007267//cell-cell signaling,GO:0008083//growth factor activity,K04358//MAPK signaling pathway;Pathways in cancer;Regulation of actin cytoskeleton;Melanoma
225689,0,0,36,0,0,3,0,0,3,0,0,0,MAPK15;mitogen-activated protein kinase 15,GO:0005634//nucleus;GO:0005622//intracellular;GO:0005576//extracellular region,GO:0000165//MAPK cascade;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001934//positive regulation of protein phosphorylation;GO:0008156//negative regulation of DNA replication;GO:0031398//positive regulation of protein ubiquitination;GO:0046777//protein autophosphorylation;GO:0032355//response to estradiol;GO:0045732//positive regulation of protein catabolic process,GO:0017124//SH3 domain binding;GO:0004707//MAP kinase activity;GO:0005524//ATP binding,-
2257,0,0,26,0,20,0,0,47,63,0,0,0,FGF12;fibroblast growth factor 12,GO:0005615//extracellular space;GO:0005634//nucleus,GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0003254//regulation of membrane depolarization;GO:0050905//neuromuscular process;GO:1902305//regulation of sodium ion transmembrane transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0007165//signal transduction;GO:2001258//negative regulation of cation channel activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007254//JNK cascade;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0007507//heart development;GO:0010765//positive regulation of sodium ion transport;GO:0007267//cell-cell signaling;GO:0008344//adult locomotory behavior,GO:0008083//growth factor activity;GO:0044325//ion channel binding;GO:0008201//heparin binding;GO:0017080//sodium channel regulator activity;GO:0005104//fibroblast growth factor receptor binding,K04358//MAPK signaling pathway;Pathways in cancer;Melanoma;Regulation of actin cytoskeleton
2258,0,0,0,17,12,0,14,0,9,0,5,0,FGF13;fibroblast growth factor 13,GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030175//filopodium;GO:0014704//intercalated disc;GO:0005576//extracellular region;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005730//nucleolus;GO:0030424//axon;GO:0005634//nucleus;GO:0005874//microtubule,GO:0007267//cell-cell signaling;GO:0021766//hippocampus development;GO:0007613//memory;GO:0046785//microtubule polymerization;GO:0007165//signal transduction;GO:0045200//establishment of neuroblast polarity;GO:0045860//positive regulation of protein kinase activity;GO:0000165//MAPK cascade;GO:0021795//cerebral cortex cell migration;GO:0072659//protein localization to plasma membrane;GO:0001764//neuron migration;GO:0007399//nervous system development;GO:0007612//learning;GO:0007026//negative regulation of microtubule depolymerization;GO:0048671//negative regulation of collateral sprouting,GO:0008083//growth factor activity;GO:0048487//beta-tubulin binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0017080//sodium channel regulator activity;GO:0030295//protein kinase activator activity,K04358//MAPK signaling pathway;Pathways in cancer;Regulation of actin cytoskeleton;Melanoma
2259,0,0,0,0,0,0,0,0,24,0,0,0,FGF14;fibroblast growth factor 14,GO:0005576//extracellular region;GO:0005634//nucleus,GO:0050905//neuromuscular process;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0007267//cell-cell signaling;GO:0010765//positive regulation of sodium ion transport;GO:0008219//cell death;GO:0008344//adult locomotory behavior;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0007254//JNK cascade,GO:0008201//heparin binding;GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity,K04358//Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Melanoma
226,0,61,3,22,121,15,13,130,16,0,0,0,"ALDOA;aldolase A, fructose-bisphosphate",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0031674//I band;GO:0031430//M band;GO:0005634//nucleus,"GO:0044281//small molecule metabolic process;GO:0051289//protein homotetramerization;GO:0008360//regulation of cell shape;GO:0006000//fructose metabolic process;GO:0006094//gluconeogenesis;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0030168//platelet activation;GO:0006941//striated muscle contraction;GO:0005975//carbohydrate metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0006754//ATP biosynthetic process;GO:0007015//actin filament organization;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0046716//muscle cell cellular homeostasis",GO:0003779//actin binding;GO:0070061//fructose binding;GO:0042802//identical protein binding;GO:0004332//fructose-bisphosphate aldolase activity;GO:0015631//tubulin binding;GO:0008092//cytoskeletal protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,"K01623//Fructose and mannose metabolism;Sulfur metabolism;Metabolic pathways;Pentose phosphate pathway;Phenylalanine, tyrosine and tryptophan biosynthesis;Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Cysteine and methionine metabolism"
2260,0,0,0,0,0,23,73,0,70,0,16,0,FGFR1;fibroblast growth factor receptor 1,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005829//cytosol,"GO:0021847//ventricular zone neuroblast division;GO:0006351//transcription, DNA-templated;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048339//paraxial mesoderm development;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0043009//chordate embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0042472//inner ear morphogenesis;GO:0045087//innate immune response;GO:0030326//embryonic limb morphogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0048469//cell maturation;GO:0001759//organ induction;GO:0001525//angiogenesis;GO:0001764//neuron migration;GO:0001501//skeletal system development;GO:0045595//regulation of cell differentiation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0008286//insulin receptor signaling pathway;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0016477//cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045787//positive regulation of cell cycle;GO:0042474//middle ear morphogenesis;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0045666//positive regulation of neuron differentiation;GO:0010863//positive regulation of phospholipase C activity;GO:0010518//positive regulation of phospholipase activity;GO:0042473//outer ear morphogenesis;GO:0060445//branching involved in salivary gland morphogenesis;GO:0000165//MAPK cascade;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0002062//chondrocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048378//regulation of lateral mesodermal cell fate specification;GO:0007411//axon guidance;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007605//sensory perception of sound;GO:0001701//in utero embryonic development;GO:0060484//lung-associated mesenchyme development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048762//mesenchymal cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035607//fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development;GO:0006468//protein phosphorylation;GO:0060117//auditory receptor cell development;GO:0030901//midbrain development;GO:0001657//ureteric bud development;GO:0046777//protein autophosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0048705//skeletal system morphogenesis",GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0004713//protein tyrosine kinase activity;GO:0017134//fibroblast growth factor binding,K04362//Regulation of actin cytoskeleton;Melanoma;MAPK signaling pathway;Pathways in cancer;Adherens junction;Prostate cancer
2261,0,0,0,1,0,0,14,25,19,0,9,0,FGFR3;fibroblast growth factor receptor 3,GO:0005925//focal adhesion;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0009986//cell surface;GO:0009898//cytoplasmic side of plasma membrane,GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0002089//lens morphogenesis in camera-type eye;GO:0070977//bone maturation;GO:0003416//endochondral bone growth;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0002009//morphogenesis of an epithelium;GO:0043525//positive regulation of neuron apoptotic process;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0045839//negative regulation of mitosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0072148//epithelial cell fate commitment;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048712//negative regulation of astrocyte differentiation;GO:0061144//alveolar secondary septum development;GO:0035019//somatic stem cell maintenance;GO:0035988//chondrocyte proliferation;GO:0007259//JAK-STAT cascade;GO:0031398//positive regulation of protein ubiquitination;GO:0001501//skeletal system development;GO:0060349//bone morphogenesis;GO:0048640//negative regulation of developmental growth;GO:0030282//bone mineralization;GO:0008286//insulin receptor signaling pathway;GO:0070307//lens fiber cell development;GO:0048678//response to axon injury;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0000165//MAPK cascade;GO:0010518//positive regulation of phospholipase activity;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060113//inner ear receptor cell differentiation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002062//chondrocyte differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0060385//axonogenesis involved in innervation;GO:0001958//endochondral ossification;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0048546//digestive tract morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021762//substantia nigra development;GO:0022010//central nervous system myelination;GO:0046777//protein autophosphorylation;GO:0045597//positive regulation of cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:1902178//fibroblast growth factor receptor apoptotic signaling pathway;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0090102//cochlea development;GO:0038095//Fc-epsilon receptor signaling pathway,GO:0005524//ATP binding;GO:0017134//fibroblast growth factor binding;GO:0004713//protein tyrosine kinase activity;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0005515//protein binding,K05094//Bladder cancer;Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Endocytosis
2262,0,0,0,0,0,0,16,0,21,0,0,0,GPC5;glypican 5,GO:0005887//integral component of plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005796//Golgi lumen,"GO:0007603//phototransduction, visible light;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0001523//retinoid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process",GO:0043395//heparan sulfate proteoglycan binding,-
2263,11,0,0,0,0,11,8,26,89,0,5,0,FGFR2;fibroblast growth factor receptor 2,GO:0005730//nucleolus;GO:0060076//excitatory synapse;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005737//cytoplasm;GO:0005938//cell cortex,GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0033688//regulation of osteoblast proliferation;GO:0060915//mesenchymal cell differentiation involved in lung development;GO:0051150//regulation of smooth muscle cell differentiation;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0060688//regulation of morphogenesis of a branching structure;GO:0060349//bone morphogenesis;GO:0008286//insulin receptor signaling pathway;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0070307//lens fiber cell development;GO:0061031//endodermal digestive tract morphogenesis;GO:0060529//squamous basal epithelial stem cell differentiation involved in prostate gland acinus development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060667//branch elongation involved in salivary gland morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0048333//mesodermal cell differentiation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0060615//mammary gland bud formation;GO:0048568//embryonic organ development;GO:0045839//negative regulation of mitosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0042476//odontogenesis;GO:0030901//midbrain development;GO:0001657//ureteric bud development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0045667//regulation of osteoblast differentiation;GO:0060348//bone development;GO:0060595//fibroblast growth factor receptor signaling pathway involved in mammary gland specification;GO:0060449//bud elongation involved in lung branching;GO:0048755//branching morphogenesis of a nerve;GO:0001701//in utero embryonic development;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0021769//orbitofrontal cortex development;GO:0010453//regulation of cell fate commitment;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0048557//embryonic digestive tract morphogenesis;GO:0048286//lung alveolus development;GO:0035264//multicellular organism growth;GO:0010518//positive regulation of phospholipase activity;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060174//limb bud formation;GO:0016331//morphogenesis of embryonic epithelium;GO:0060463//lung lobe morphogenesis;GO:0048489//synaptic vesicle transport;GO:0051781//positive regulation of cell division;GO:0040014//regulation of multicellular organism growth;GO:0045787//positive regulation of cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009791//post-embryonic development;GO:0030855//epithelial cell differentiation;GO:0030282//bone mineralization;GO:0048730//epidermis morphogenesis;GO:0045087//innate immune response;GO:0048562//embryonic organ morphogenesis;GO:0021860//pyramidal neuron development;GO:0043410//positive regulation of MAPK cascade;GO:0048565//digestive tract development;GO:0060442//branching involved in prostate gland morphogenesis;GO:0001525//angiogenesis;GO:0035602//fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow;GO:0021847//ventricular zone neuroblast division;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0009887//organ morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0032808//lacrimal gland development;GO:0035265//organ growth;GO:0048608//reproductive structure development;GO:0060512//prostate gland morphogenesis;GO:0003149//membranous septum morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060365//coronal suture morphogenesis;GO:0046777//protein autophosphorylation;GO:0048705//skeletal system morphogenesis;GO:0022612//gland morphogenesis;GO:0060601//lateral sprouting from an epithelium;GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030324//lung development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035607//fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development;GO:0060484//lung-associated mesenchyme development;GO:0045165//cell fate commitment;GO:0060916//mesenchymal cell proliferation involved in lung development;GO:0060523//prostate epithelial cord elongation;GO:0030916//otic vesicle formation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0031069//hair follicle morphogenesis;GO:0007409//axonogenesis;GO:0048762//mesenchymal cell differentiation;GO:0007528//neuromuscular junction development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0035603//fibroblast growth factor receptor signaling pathway involved in hemopoiesis;GO:0035604//fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0008589//regulation of smoothened signaling pathway,GO:0008201//heparin binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0004713//protein tyrosine kinase activity;GO:0017134//fibroblast growth factor binding;GO:0005524//ATP binding,K05093//Regulation of actin cytoskeleton;Endocytosis;Pathways in cancer;MAPK signaling pathway;Prostate cancer;K04362//Prostate cancer;Adherens junction;Regulation of actin cytoskeleton;Melanoma;Pathways in cancer;MAPK signaling pathway;K05094//Bladder cancer;MAPK signaling pathway;Pathways in cancer;Endocytosis;Regulation of actin cytoskeleton
2264,0,0,17,0,0,0,24,0,22,0,0,0,FGFR4;fibroblast growth factor receptor 4,GO:0005730//nucleolus;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005768//endosome;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005737//cytoplasm,GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045862//positive regulation of proteolysis;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0055062//phosphate ion homeostasis;GO:0048554//positive regulation of metalloenzyme activity;GO:0061144//alveolar secondary septum development;GO:0016477//cell migration;GO:0070857//regulation of bile acid biosynthetic process;GO:2000188//regulation of cholesterol homeostasis;GO:0046777//protein autophosphorylation;GO:0010715//regulation of extracellular matrix disassembly;GO:0019216//regulation of lipid metabolic process;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:2000573//positive regulation of DNA biosynthetic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0042593//glucose homeostasis;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001759//organ induction,GO:0004713//protein tyrosine kinase activity;GO:0017134//fibroblast growth factor binding;GO:0005524//ATP binding;GO:0008201//heparin binding;GO:0005007//fibroblast growth factor-activated receptor activity,K05094//Regulation of actin cytoskeleton;Endocytosis;Pathways in cancer;MAPK signaling pathway;Bladder cancer;K05095//MAPK signaling pathway;Endocytosis;Regulation of actin cytoskeleton
2267,0,0,0,0,0,0,0,0,8,0,0,0,FGL1;fibrinogen-like 1,GO:0005577//fibrinogen complex;GO:0070062//extracellular vesicular exosome,GO:0035634//response to stilbenoid;GO:0060612//adipose tissue development;GO:0010906//regulation of glucose metabolic process;GO:0008203//cholesterol metabolic process,-,K03905//Complement and coagulation cascades;Staphylococcus aureus infection
2268,0,0,0,0,0,26,0,0,77,0,12,0,"FGR;FGR proto-oncogene, Src family tyrosine kinase",GO:0005856//cytoskeleton;GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane,GO:0045859//regulation of protein kinase activity;GO:0043306//positive regulation of mast cell degranulation;GO:0046777//protein autophosphorylation;GO:0007229//integrin-mediated signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0045088//regulation of innate immune response;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0050764//regulation of phagocytosis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0006468//protein phosphorylation;GO:0007596//blood coagulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045087//innate immune response;GO:0008360//regulation of cell shape;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0009615//response to virus;GO:0030335//positive regulation of cell migration;GO:0050715//positive regulation of cytokine secretion;GO:0002768//immune response-regulating cell surface receptor signaling pathway,GO:0005524//ATP binding;GO:0034987//immunoglobulin receptor binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0019901//protein kinase binding;GO:0001784//phosphotyrosine binding;GO:0004713//protein tyrosine kinase activity;GO:0034988//Fc-gamma receptor I complex binding;GO:0005515//protein binding,K08891//Epstein-Barr virus infection;Chemokine signaling pathway
2271,74,22,0,1,26,5,0,0,26,0,0,0,FH;fumarate hydratase,GO:0045239//tricarboxylic acid cycle enzyme complex;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044281//small molecule metabolic process;GO:0048873//homeostasis of number of cells within a tissue;GO:0006106//fumarate metabolic process,GO:0004333//fumarate hydratase activity,K01679//Biosynthesis of secondary metabolites;Renal cell carcinoma;Pathways in cancer;Microbial metabolism in diverse environments;Carbon fixation pathways in prokaryotes;Metabolic pathways;Citrate cycle (TCA cycle)
2272,0,0,0,0,0,0,0,0,27,0,0,0,FHIT;fragile histidine triad,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006260//DNA replication;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006163//purine nucleotide metabolic process;GO:0009117//nucleotide metabolic process;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006351//transcription, DNA-templated",GO:0047710//bis(5'-adenosyl)-triphosphatase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0003824//catalytic activity,K01522//Purine metabolism;Small cell lung cancer;Non-small cell lung cancer
2273,0,0,0,0,0,24,23,0,15,0,10,0,FHL1;four and a half LIM domains 1,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0043268//positive regulation of potassium ion transport;GO:0030308//negative regulation of cell growth;GO:0003254//regulation of membrane depolarization;GO:0009887//organ morphogenesis;GO:0007517//muscle organ development;GO:0030154//cell differentiation;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle,GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
2274,0,0,0,11,20,33,53,3,12,0,0,0,FHL2;four and a half LIM domains 2,GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0005654//nucleoplasm;GO:0031430//M band;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0030521//androgen receptor signaling pathway;GO:0001649//osteoblast differentiation;GO:0009725//response to hormone;GO:0044281//small molecule metabolic process;GO:0055015//ventricular cardiac muscle cell development;GO:0055014//atrial cardiac muscle cell development;GO:0006351//transcription, DNA-templated;GO:0060347//heart trabecula formation;GO:0043066//negative regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0050681//androgen receptor binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding,K14380//Osteoclast differentiation
2275,0,0,0,0,0,0,0,0,11,0,11,0,FHL3;four and a half LIM domains 3,GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0001725//stress fiber;GO:0005634//nucleus,GO:0030036//actin cytoskeleton organization;GO:0007517//muscle organ development,GO:0003779//actin binding;GO:0008270//zinc ion binding,K14380//Osteoclast differentiation
2277,0,0,0,0,0,10,0,0,12,0,0,0,FIGF;c-fos induced growth factor (vascular endothelial growth factor D),GO:0005576//extracellular region;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space,GO:0051781//positive regulation of cell division;GO:0008284//positive regulation of cell proliferation;GO:0050918//positive chemotaxis;GO:0030154//cell differentiation;GO:0030168//platelet activation;GO:0001525//angiogenesis;GO:0050930//induction of positive chemotaxis;GO:0008283//cell proliferation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0060754//positive regulation of mast cell chemotaxis;GO:0002576//platelet degranulation,GO:0005161//platelet-derived growth factor receptor binding;GO:0043185//vascular endothelial growth factor receptor 3 binding;GO:0042803//protein homodimerization activity;GO:0005172//vascular endothelial growth factor receptor binding;GO:0042056//chemoattractant activity;GO:0008083//growth factor activity,K05449//Renal cell carcinoma;Focal adhesion;Bladder cancer;mTOR signaling pathway;Pancreatic cancer;Cytokine-cytokine receptor interaction;Pathways in cancer
22794,0,36,0,33,51,0,0,0,0,0,0,0,CASC3;cancer susceptibility candidate 3,GO:0048471//perinuclear region of cytoplasm;GO:0016607//nuclear speck;GO:0030529//ribonucleoprotein complex;GO:0005829//cytosol;GO:0035145//exon-exon junction complex,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0008298//intracellular mRNA localization;GO:0051028//mRNA transport;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0006950//response to stress;GO:0006417//regulation of translation",GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019899//enzyme binding,K14323//mRNA surveillance pathway;RNA transport
22795,0,0,2,87,115,14,68,0,43,370,99,0,NID2;nidogen 2 (osteonidogen),GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005604//basement membrane;GO:0009986//cell surface;GO:0031012//extracellular matrix,GO:0030198//extracellular matrix organization;GO:0007160//cell-matrix adhesion;GO:0007155//cell adhesion;GO:0071711//basement membrane organization,GO:0005518//collagen binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,-
22796,0,27,17,17,65,14,0,165,8,0,0,0,COG2;component of oligomeric golgi complex 2,GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0017119//Golgi transport complex;GO:0000139//Golgi membrane,GO:0006486//protein glycosylation;GO:0009312//oligosaccharide biosynthetic process;GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0007030//Golgi organization,GO:0005515//protein binding;GO:0032403//protein complex binding;GO:0008565//protein transporter activity,-
22797,0,0,0,0,0,0,42,0,39,0,0,0,TFEC;transcription factor EC,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0034605//cellular response to heat;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0046983//protein dimerization activity;GO:0003714//transcription corepressor activity,-
22798,78,0,0,0,0,28,25,0,41,0,0,0,"LAMB4;laminin, beta 4",GO:0005604//basement membrane,GO:0007155//cell adhesion,-,K06245//ECM-receptor interaction;Pathways in cancer;Toxoplasmosis;Focal adhesion;Small cell lung cancer;Amoebiasis
2280,0,1,0,53,326,0,1,0,12,0,0,0,"FKBP1A;FK506 binding protein 1A, 12kDa",GO:0030018//Z disc;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0014802//terminal cisterna;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043206//extracellular fibril organization;GO:0006458//'de novo' protein folding;GO:0022417//protein maturation by protein folding;GO:0032880//regulation of protein localization;GO:0000413//protein peptidyl-prolyl isomerization;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0042110//T cell activation;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0032513//negative regulation of protein phosphatase type 2B activity;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0006457//protein folding;GO:0032092//positive regulation of protein binding;GO:0032925//regulation of activin receptor signaling pathway;GO:0042026//protein refolding;GO:1902991//regulation of amyloid precursor protein catabolic process;GO:0060347//heart trabecula formation;GO:0003007//heart morphogenesis;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0031398//positive regulation of protein ubiquitination;GO:0050776//regulation of immune response;GO:1990000//amyloid fibril formation;GO:0007183//SMAD protein complex assembly;GO:0061077//chaperone-mediated protein folding;GO:0070588//calcium ion transmembrane transport,GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0004871//signal transducer activity;GO:0005528//FK506 binding;GO:0019855//calcium channel inhibitor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0046332//SMAD binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0005515//protein binding;GO:0048185//activin binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0044325//ion channel binding;GO:0005024//transforming growth factor beta-activated receptor activity,-
22800,1,92,0,6,31,22,2,0,37,0,4,0,RRAS2;related RAS viral (r-ras) oncogene homolog 2,GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion,GO:0006184//GTP catabolic process;GO:0001649//osteoblast differentiation;GO:0007265//Ras protein signal transduction;GO:0030335//positive regulation of cell migration,GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07830//HTLV-I infection;Regulation of actin cytoskeleton;MAPK signaling pathway;Tight junction
22801,265,0,0,0,3,10,16,1,85,3,14,0,"ITGA11;integrin, alpha 11",GO:0016020//membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0008305//integrin complex,GO:0033627//cell adhesion mediated by integrin;GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0006929//substrate-dependent cell migration;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0001649//osteoblast differentiation,GO:0046872//metal ion binding;GO:0005518//collagen binding,K06587//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Regulation of actin cytoskeleton;ECM-receptor interaction;Dilated cardiomyopathy;Focal adhesion
22802,0,15,0,0,0,2,2,64,65,0,0,0,CLCA4;chloride channel accessory 4,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane,GO:1902476//chloride transmembrane transport;GO:0006810//transport;GO:0006821//chloride transport,GO:0005254//chloride channel activity,K05030//Pancreatic secretion;Olfactory transduction
22803,0,77,0,33,147,14,0,32,25,0,6,0,XRN2;5'-3' exoribonuclease 2,GO:0016235//aggresome;GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,"GO:0006401//RNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0006396//RNA processing;GO:0016049//cell growth;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0000738//DNA catabolic process, exonucleolytic;GO:0007283//spermatogenesis;GO:0006353//DNA-templated transcription, termination;GO:0006397//mRNA processing",GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0008409//5'-3' exonuclease activity;GO:0004534//5'-3' exoribonuclease activity;GO:0004518//nuclease activity,K12619//RNA degradation;Ribosome biogenesis in eukaryotes
22806,0,0,0,0,0,0,0,0,29,0,8,0,IKZF3;IKAROS family zinc finger 3 (Aiolos),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane,"GO:0006351//transcription, DNA-templated;GO:0030888//regulation of B cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0007498//mesoderm development;GO:0042981//regulation of apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045619//regulation of lymphocyte differentiation;GO:0042113//B cell activation",GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
22807,0,2,0,22,104,17,32,0,63,0,4,0,IKZF2;IKAROS family zinc finger 2 (Helios),GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,-
22808,212,0,0,10,0,0,0,0,25,0,0,165,MRAS;muscle RAS oncogene homolog,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process;GO:0007265//Ras protein signal transduction;GO:0007517//muscle organ development;GO:0007275//multicellular organismal development,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0030742//GTP-dependent protein binding,K07831//HTLV-I infection;Regulation of actin cytoskeleton;MAPK signaling pathway;Tight junction
22809,69,28,28,35,139,0,0,0,22,0,148,0,ATF5;activating transcription factor 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048712//negative regulation of astrocyte differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009791//post-embryonic development;GO:0006351//transcription, DNA-templated;GO:0021891//olfactory bulb interneuron development;GO:0035264//multicellular organism growth;GO:0043066//negative regulation of apoptotic process",GO:0031072//heat shock protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
2281,0,0,0,0,0,0,13,0,15,0,0,0,"FKBP1B;FK506 binding protein 1B, 12.6 kDa",GO:0033017//sarcoplasmic reticulum membrane;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0034704//calcium channel complex;GO:0016020//membrane;GO:0005829//cytosol,GO:0070588//calcium ion transmembrane transport;GO:0019227//neuronal action potential propagation;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0061077//chaperone-mediated protein folding;GO:0006939//smooth muscle contraction;GO:0030073//insulin secretion;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0033197//response to vitamin E;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042026//protein refolding;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0032513//negative regulation of protein phosphatase type 2B activity;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0042542//response to hydrogen peroxide;GO:0051775//response to redox state;GO:0051480//cytosolic calcium ion homeostasis;GO:0051284//positive regulation of sequestering of calcium ion;GO:0000413//protein peptidyl-prolyl isomerization;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0048680//positive regulation of axon regeneration;GO:0022417//protein maturation by protein folding;GO:0010459//negative regulation of heart rate;GO:0009749//response to glucose;GO:0042098//T cell proliferation;GO:0006458//'de novo' protein folding;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0035584//calcium-mediated signaling using intracellular calcium source,GO:0005102//receptor binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0030551//cyclic nucleotide binding;GO:0019855//calcium channel inhibitor activity;GO:0005528//FK506 binding;GO:0005219//ryanodine-sensitive calcium-release channel activity,-
22818,0,12,2,37,154,0,20,0,49,0,0,0,"COPZ1;coatomer protein complex, subunit zeta 1",GO:0005829//cytosol;GO:0030126//COPI vesicle coat,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0048205//COPI coating of Golgi vesicle",-,K02604//Cell cycle;Cell cycle - yeast;Meiosis - yeast;K12399//Lysosome
22820,0,68,4,69,407,0,1,0,15,0,11,0,"COPG1;coatomer protein complex, subunit gamma 1",GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030126//COPI vesicle coat,"GO:0072384//organelle transport along microtubule;GO:0051683//establishment of Golgi localization;GO:0048205//COPI coating of Golgi vesicle;GO:0061024//membrane organization;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport",GO:0005198//structural molecule activity;GO:0005515//protein binding,-
22821,0,0,0,0,1,49,28,2,60,0,11,0,RASA3;RAS p21 protein activator 3,GO:0005737//cytoplasm;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane,GO:0032320//positive regulation of Ras GTPase activity;GO:0070588//calcium ion transmembrane transport;GO:0035556//intracellular signal transduction;GO:0007165//signal transduction;GO:0046580//negative regulation of Ras protein signal transduction,GO:0015278//calcium-release channel activity;GO:0046872//metal ion binding;GO:0005096//GTPase activator activity;GO:0005099//Ras GTPase activator activity,K12380//MAPK signaling pathway - fly
22822,0,0,0,0,0,7,0,0,53,5,0,0,"PHLDA1;pleckstrin homology-like domain, family A, member 1",GO:0005730//nucleolus;GO:0030659//cytoplasmic vesicle membrane,GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0021879//forebrain neuron differentiation;GO:0045210//FasL biosynthetic process,GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
22823,0,0,0,0,18,0,25,0,63,0,4,0,MTF2;metal response element binding transcription factor 2,GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0061087//positive regulation of histone H3-K27 methylation;GO:0048863//stem cell differentiation;GO:0007379//segment specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0061086//negative regulation of histone H3-K27 methylation,GO:0035064//methylated histone binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
22824,0,0,1,0,30,0,0,0,79,0,0,0,HSPA4L;heat shock 70kDa protein 4-like,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006986//response to unfolded protein;GO:0006457//protein folding,GO:0005524//ATP binding,K09485//Protein processing in endoplasmic reticulum
22826,0,44,0,19,106,0,0,0,5,0,0,0,"DNAJC8;DnaJ (Hsp40) homolog, subfamily C, member 8",GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0010467//gene expression",-,-
22827,0,27,49,21,34,0,0,70,10,0,10,1,PUF60;poly-U binding splicing factor 60KDa,GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0030529//ribonucleoprotein complex,"GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K12838//Spliceosome
22828,1,36,3,10,216,0,0,0,38,35,0,0,SCAF8;SR-related CTD-associated factor 8,GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016363//nuclear matrix,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0043175//RNA polymerase core enzyme binding,K05731//Chemokine signaling pathway;Regulation of actin cytoskeleton
22832,0,35,0,4,11,22,1,0,62,0,0,0,CEP162;centrosomal protein 162kDa,GO:0005634//nucleus;GO:0005813//centrosome;GO:0005819//spindle;GO:0005814//centriole;GO:0005879//axonemal microtubule,GO:0042384//cilium assembly,GO:0005515//protein binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
22834,79,96,1,152,280,18,0,0,98,0,4,0,ZNF652;zinc finger protein 652,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
22835,0,0,24,16,65,0,0,0,6,0,0,2,ZFP30;ZFP30 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
22836,91,40,1,51,175,0,25,56,76,0,0,0,RHOBTB3;Rho-related BTB domain containing 3,GO:0005794//Golgi apparatus,"GO:0042147//retrograde transport, endosome to Golgi;GO:0006200//ATP catabolic process;GO:0007264//small GTPase mediated signal transduction",GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0016887//ATPase activity,-
22837,0,49,0,17,185,21,19,0,58,129,0,399,COBLL1;cordon-bleu WH2 repeat protein-like 1,GO:0070062//extracellular vesicular exosome,-,GO:0003779//actin binding,-
22838,0,0,0,0,1,0,0,0,20,0,5,0,RNF44;ring finger protein 44,-,-,GO:0008270//zinc ion binding,-
22839,53,25,0,0,1,7,0,58,17,0,0,0,"DLGAP4;discs, large (Drosophila) homolog-associated protein 4",GO:0016020//membrane;GO:0045202//synapse,GO:0007267//cell-cell signaling,GO:0005515//protein binding,K15008//Glutamatergic synapse
22841,0,1,0,4,54,25,0,0,23,0,0,0,RAB11FIP2;RAB11 family interacting protein 2 (class I),GO:0005634//nucleus;GO:0030659//cytoplasmic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0055038//recycling endosome membrane;GO:0005886//plasma membrane;GO:0005768//endosome,GO:0030010//establishment of cell polarity;GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0055085//transmembrane transport;GO:0006833//water transport;GO:0045055//regulated secretory pathway;GO:0015031//protein transport,GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K12484//Endocytosis
22843,116,46,0,31,92,14,83,0,20,0,46,0,"PPM1E;protein phosphatase, Mg2+/Mn2+ dependent, 1E",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0043234//protein complex,GO:0035970//peptidyl-threonine dephosphorylation;GO:0051496//positive regulation of stress fiber assembly;GO:0035690//cellular response to drug;GO:0006469//negative regulation of protein kinase activity,GO:0004722//protein serine/threonine phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
22844,0,0,0,0,0,15,0,19,54,0,21,0,FRMPD1;FERM and PDZ domain containing 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005856//cytoskeleton,-,-,K05725//Regulation of actin cytoskeleton;ErbB signaling pathway;Amoebiasis;VEGF signaling pathway;Focal adhesion;Chemokine signaling pathway;Pathways in cancer;Axon guidance;Bacterial invasion of epithelial cells;Transcriptional misregulation in cancer;Small cell lung cancer;Leukocyte transendothelial migration;K00948//Metabolic pathways;Thiamine metabolism;Pentose phosphate pathway;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Purine metabolism
22845,0,0,0,0,0,0,0,57,15,67,16,0,DOLK;dolichol kinase,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0043048//dolichyl monophosphate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0016310//phosphorylation,GO:0004168//dolichol kinase activity,K00902//N-Glycan biosynthesis;Metabolic pathways
22846,0,0,51,0,0,17,0,0,32,0,1,0,VASH1;vasohibin 1,GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0045177//apical part of cell;GO:0005737//cytoplasm,GO:0010596//negative regulation of endothelial cell migration;GO:2000772//regulation of cellular senescence;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0009611//response to wounding;GO:0001937//negative regulation of endothelial cell proliferation;GO:0007050//cell cycle arrest;GO:0001525//angiogenesis;GO:1901491//negative regulation of lymphangiogenesis;GO:0016525//negative regulation of angiogenesis,-,-
22847,55,41,0,35,38,0,9,0,50,0,0,0,ZNF507;zinc finger protein 507,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
22848,0,49,0,95,230,25,115,12,107,328,0,0,AAK1;AP2 associated kinase 1,GO:0030136//clathrin-coated vesicle;GO:0031252//cell leading edge;GO:0005905//coated pit;GO:0043195//terminal bouton;GO:0019897//extrinsic component of plasma membrane,GO:0032880//regulation of protein localization;GO:0006897//endocytosis;GO:0046777//protein autophosphorylation;GO:0045747//positive regulation of Notch signaling pathway;GO:2000369//regulation of clathrin-mediated endocytosis;GO:0006468//protein phosphorylation;GO:0050821//protein stabilization,GO:0005112//Notch binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding;GO:0004674//protein serine/threonine kinase activity,-
22849,0,0,31,49,61,0,0,47,29,0,34,0,CPEB3;cytoplasmic polyadenylation element binding protein 3,GO:0043005//neuron projection;GO:0097440//apical dendrite;GO:0030425//dendrite;GO:0045202//synapse;GO:0030014//CCR4-NOT complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0060998//regulation of dendritic spine development;GO:1900248//negative regulation of cytoplasmic translational elongation;GO:1900365//positive regulation of mRNA polyadenylation;GO:0017148//negative regulation of translation;GO:0007616//long-term memory;GO:0071230//cellular response to amino acid stimulus;GO:0060999//positive regulation of dendritic spine development;GO:0045727//positive regulation of translation;GO:0061158//3'-UTR-mediated mRNA destabilization;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048167//regulation of synaptic plasticity;GO:0006412//translation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","GO:0003723//RNA binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0035613//RNA stem-loop binding;GO:0003730//mRNA 3'-UTR binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding",K02602//Oocyte meiosis;Dorso-ventral axis formation;Progesterone-mediated oocyte maturation
22850,1,0,0,0,35,18,0,0,23,0,4,0,ADNP2;ADNP homeobox 2,GO:0005634//nucleus,"GO:0071300//cellular response to retinoic acid;GO:0006351//transcription, DNA-templated;GO:0034599//cellular response to oxidative stress;GO:0030307//positive regulation of cell growth;GO:0030182//neuron differentiation;GO:0060548//negative regulation of cell death;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
22852,72,0,0,0,21,49,56,29,33,0,0,0,ANKRD26;ankyrin repeat domain 26,GO:0005813//centrosome;GO:0005884//actin filament,GO:0019217//regulation of fatty acid metabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0046621//negative regulation of organ growth;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0040015//negative regulation of multicellular organism growth;GO:0060259//regulation of feeding behavior;GO:0042593//glucose homeostasis;GO:0046627//negative regulation of insulin receptor signaling pathway,-,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12478//Endocytosis;Phagosome;Tuberculosis
22853,75,0,0,1,0,9,29,0,32,208,0,0,LMTK2;lemur tyrosine kinase 2,GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,GO:0006468//protein phosphorylation;GO:0001881//receptor recycling;GO:0018107//peptidyl-threonine phosphorylation;GO:0045022//early endosome to late endosome transport;GO:0043086//negative regulation of catalytic activity;GO:0018105//peptidyl-serine phosphorylation;GO:0046777//protein autophosphorylation;GO:0033572//transferrin transport;GO:0032456//endocytic recycling,GO:0005515//protein binding;GO:0070853//myosin VI binding;GO:0004674//protein serine/threonine kinase activity;GO:0004864//protein phosphatase inhibitor activity;GO:0005524//ATP binding,-
22854,0,0,0,0,0,0,10,0,21,112,6,0,NTNG1;netrin G1,GO:0046658//anchored component of plasma membrane,GO:0007409//axonogenesis,GO:0005515//protein binding,K07522//Axon guidance
22856,80,31,0,0,57,40,3,22,29,0,0,0,CHSY1;chondroitin sulfate synthase 1,GO:0005576//extracellular region;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030279//negative regulation of ossification;GO:0031667//response to nutrient levels,GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity;GO:0046872//metal ion binding,K13499//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
22858,0,14,1,88,182,15,0,0,78,0,0,1,ICK;intestinal cell (MAK-like) kinase,GO:0005634//nucleus;GO:0005829//cytosol,GO:0051726//regulation of cell cycle;GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007275//multicellular organismal development,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0000287//magnesium ion binding,-
22859,100,45,34,0,5,4,0,6,38,0,14,0,LPHN1;latrophilin 1,GO:0030426//growth cone;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0030424//axon,GO:0007186//G-protein coupled receptor signaling pathway;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007218//neuropeptide signaling pathway;GO:0090129//positive regulation of synapse maturation,GO:0004930//G-protein coupled receptor activity;GO:0050839//cell adhesion molecule binding;GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0016524//latrotoxin receptor activity,-
2286,0,0,0,0,0,0,0,0,10,0,0,0,"FKBP2;FK506 binding protein 2, 13kDa",GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0061077//chaperone-mediated protein folding;GO:0000413//protein peptidyl-prolyl isomerization,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0005528//FK506 binding,-
22861,0,35,0,11,0,13,0,0,42,0,12,0,"NLRP1;NLR family, pyrin domain containing 1",GO:0072558//NLRP1 inflammasome complex;GO:0005829//cytosol;GO:0005622//intracellular;GO:0005634//nucleus,"GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0042742//defense response to bacterium;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0051402//neuron apoptotic process;GO:0050727//regulation of inflammatory response;GO:0032495//response to muramyl dipeptide;GO:0006915//apoptotic process;GO:0045087//innate immune response;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process",GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005515//protein binding,K12798//NOD-like receptor signaling pathway
22862,25,40,1,54,302,56,2,0,23,4,0,0,FNDC3A;fibronectin type III domain containing 3A,GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0012506//vesicle membrane;GO:0001669//acrosomal vesicle;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,GO:0060009//Sertoli cell development;GO:0007286//spermatid development;GO:0016337//single organismal cell-cell adhesion;GO:0009566//fertilization,GO:0044822//poly(A) RNA binding,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
22863,0,0,62,4,44,4,17,0,30,131,0,235,ATG14;autophagy related 14,GO:0034045//pre-autophagosomal structure membrane;GO:0045335//phagocytic vesicle;GO:0005789//endoplasmic reticulum membrane;GO:0005930//axoneme;GO:0005776//autophagic vacuole;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0010508//positive regulation of autophagy;GO:0000045//autophagic vacuole assembly;GO:0008333//endosome to lysosome transport,GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
22864,47,81,1,114,283,29,22,0,28,138,9,0,R3HDM2;R3H domain containing 2,GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,K02360//Dorso-ventral axis formation
22865,0,0,0,5,0,0,30,0,19,0,0,0,"SLITRK3;SLIT and NTRK-like family, member 3",GO:0016021//integral component of membrane,GO:0007409//axonogenesis,-,-
22866,0,1,0,3,0,0,23,0,58,0,4,0,CNKSR2;connector enhancer of kinase suppressor of Ras 2,GO:0045211//postsynaptic membrane;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0043025//neuronal cell body,GO:0009966//regulation of signal transduction,GO:0042802//identical protein binding,K00901//Glycerophospholipid metabolism;Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways
22868,0,1,0,19,0,0,42,0,38,63,0,0,FASTKD2;FAST kinase domains 2,GO:0005739//mitochondrion,GO:0006468//protein phosphorylation;GO:0045333//cellular respiration,GO:0004672//protein kinase activity;GO:0044822//poly(A) RNA binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
22869,0,0,0,11,78,0,39,0,6,0,14,0,ZNF510;zinc finger protein 510,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
2287,0,0,0,26,59,0,0,90,8,0,0,144,"FKBP3;FK506 binding protein 3, 25kDa",GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0000413//protein peptidyl-prolyl isomerization;GO:0061077//chaperone-mediated protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0005528//FK506 binding,-
22870,0,0,0,1,0,10,3,52,58,0,0,0,"PPP6R1;protein phosphatase 6, regulatory subunit 1",GO:0005737//cytoplasm,GO:0043666//regulation of phosphoprotein phosphatase activity,GO:0005515//protein binding;GO:0019903//protein phosphatase binding,-
22871,168,0,0,0,0,38,0,0,12,0,0,3,NLGN1;neuroligin 1,GO:0009986//cell surface;GO:0045211//postsynaptic membrane;GO:0097481//neuronal postsynaptic density;GO:0030425//dendrite;GO:0032433//filopodium tip;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0009897//external side of plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,"GO:0097114//N-methyl-D-aspartate receptor clustering;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0007399//nervous system development;GO:1902533//positive regulation of intracellular signal transduction;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016080//synaptic vesicle targeting;GO:0051965//positive regulation of synapse assembly;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0051290//protein heterotetramerization;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0097105//presynaptic membrane assembly;GO:0006605//protein targeting;GO:0097091//synaptic vesicle clustering;GO:0051260//protein homooligomerization;GO:0060999//positive regulation of dendritic spine development;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:2000302//positive regulation of synaptic vesicle exocytosis;GO:0045184//establishment of protein localization;GO:0023041//neuronal signal transduction;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0051491//positive regulation of filopodium assembly;GO:0007416//synapse assembly;GO:0097120//receptor localization to synapse;GO:0097119//postsynaptic density protein 95 clustering;GO:0097104//postsynaptic membrane assembly;GO:0097113//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering;GO:0048789//cytoskeletal matrix organization at active zone;GO:1900244//positive regulation of synaptic vesicle endocytosis;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0072553//terminal button organization;GO:0035418//protein localization to synapse;GO:0007158//neuron cell-cell adhesion;GO:0045664//regulation of neuron differentiation;GO:1900029//positive regulation of ruffle assembly;GO:0097115//neurexin clustering",GO:0050839//cell adhesion molecule binding;GO:0030165//PDZ domain binding;GO:0042043//neurexin family protein binding;GO:0046983//protein dimerization activity;GO:0004872//receptor activity,K07378//Cell adhesion molecules (CAMs)
22872,0,46,0,6,11,0,0,0,0,0,0,0,SEC31A;SEC31 homolog A (S. cerevisiae),GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0070971//endoplasmic reticulum exit site;GO:0030127//COPII vesicle coat;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0030134//ER to Golgi transport vesicle;GO:0030120//vesicle coat;GO:0005737//cytoplasm,GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0043687//post-translational protein modification;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0048208//COPII vesicle coating;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0051592//response to calcium ion;GO:0044267//cellular protein metabolic process;GO:0015031//protein transport;GO:0061024//membrane organization,GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding,K14005//Protein processing in endoplasmic reticulum
22873,0,0,0,0,0,68,0,0,55,0,8,0,DZIP1;DAZ interacting zinc finger protein 1,GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0042384//cilium assembly;GO:0007281//germ cell development,GO:0005515//protein binding;GO:0046872//metal ion binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
22874,0,0,0,0,25,0,60,0,104,120,27,27,"PLEKHA6;pleckstrin homology domain containing, family A member 6",-,-,-,K03426//Peroxisome;Nicotinate and nicotinamide metabolism;K06082//Adherens junction
22875,0,0,0,0,12,0,0,0,11,0,2,3,ENPP4;ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative),GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030194//positive regulation of blood coagulation;GO:0007596//blood coagulation;GO:0046130//purine ribonucleoside catabolic process,GO:0046872//metal ion binding;GO:0047710//bis(5'-adenosyl)-triphosphatase activity,-
22876,0,0,0,2,8,1,18,0,98,0,0,6,INPP5F;inositol polyphosphate-5-phosphatase F,-,GO:0048015//phosphatidylinositol-mediated signaling;GO:0051896//regulation of protein kinase B signaling;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0031161//phosphatidylinositol catabolic process,GO:0042578//phosphoric ester hydrolase activity,K01099//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;K01557//Tyrosine metabolism;Metabolic pathways
22877,0,2,0,4,13,24,0,62,53,0,10,0,MLXIP;MLX interacting protein,GO:0005741//mitochondrial outer membrane;GO:0005634//nucleus,"GO:0006913//nucleocytoplasmic transport;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
22878,0,36,0,26,49,0,0,46,46,0,0,0,TRAPPC8;trafficking protein particle complex 8,GO:0005794//Golgi apparatus,GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,-
22879,0,14,1,26,104,28,1,0,29,0,1,235,MON1B;MON1 secretory trafficking family member B,-,-,GO:0005515//protein binding,-
2288,0,66,0,44,239,16,0,0,2,0,22,0,"FKBP4;FK506 binding protein 4, 59kDa",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005874//microtubule;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0044295//axonal growth cone;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0070062//extracellular vesicular exosome,GO:0046661//male sex differentiation;GO:0030521//androgen receptor signaling pathway;GO:0000413//protein peptidyl-prolyl isomerization;GO:0006825//copper ion transport;GO:0010977//negative regulation of neuron projection development;GO:0006457//protein folding;GO:0031503//protein complex localization;GO:0007566//embryo implantation;GO:0061077//chaperone-mediated protein folding;GO:0006463//steroid hormone receptor complex assembly;GO:0030850//prostate gland development;GO:0031115//negative regulation of microtubule polymerization,"GO:0030674//protein binding, bridging;GO:0005528//FK506 binding;GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0051219//phosphoprotein binding;GO:0035259//glucocorticoid receptor binding;GO:0031072//heat shock protein binding;GO:0032767//copper-dependent protein binding;GO:0048156//tau protein binding",-
22880,0,53,0,1,53,65,4,0,75,0,1,0,MORC2;MORC family CW-type zinc finger 2,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding,-
22881,0,50,172,178,203,70,0,19,58,0,120,0,ANKRD6;ankyrin repeat domain 6,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0046330//positive regulation of JNK cascade;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway",-,-
22882,0,30,0,8,111,0,9,0,16,30,0,0,ZHX2;zinc fingers and homeoboxes 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0035019//somatic stem cell maintenance;GO:0006402//mRNA catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
22883,0,39,1,7,11,18,32,24,30,0,8,0,CLSTN1;calsyntenin 1,GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0042995//cell projection;GO:0005789//endoplasmic reticulum membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0042988//X11-like protein binding;GO:0005509//calcium ion binding;GO:0019894//kinesin binding;GO:0001540//beta-amyloid binding,-
22884,0,1,0,0,0,1,3,1,11,0,1,0,WDR37;WD repeat domain 37,-,-,-,K01062//Ether lipid metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
22887,0,1,0,36,82,9,12,247,23,9,8,0,FOXJ3;forkhead box J3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
22888,0,0,2,5,2,8,3,0,16,201,0,0,UBOX5;U-box domain containing 5,GO:0005634//nucleus,GO:0000209//protein polyubiquitination,GO:0008270//zinc ion binding;GO:0034450//ubiquitin-ubiquitin ligase activity,K10600//Ubiquitin mediated proteolysis
22889,0,1,0,0,20,13,0,0,79,0,0,0,KIAA0907;KIAA0907,-,-,GO:0003723//RNA binding,-
2289,0,327,3,245,591,31,18,0,64,0,2,0,FKBP5;FK506 binding protein 5,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding;GO:0061077//chaperone-mediated protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0005528//FK506 binding,-
22890,88,15,0,14,75,1,0,0,5,0,0,32,ZBTB1;zinc finger and BTB domain containing 1,GO:0005634//nucleus;GO:0016604//nuclear body;GO:0005654//nucleoplasm,GO:0048538//thymus development;GO:2000176//positive regulation of pro-T cell differentiation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045582//positive regulation of T cell differentiation;GO:0051260//protein homooligomerization;GO:0032825//positive regulation of natural killer cell differentiation;GO:0045087//innate immune response;GO:0030183//B cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002711//positive regulation of T cell mediated immunity,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
22891,0,0,0,0,0,85,63,0,71,0,0,0,ZNF365;zinc finger protein 365,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,-,GO:0005515//protein binding,-
22893,0,0,0,0,0,0,0,0,18,0,0,0,BAHD1;bromo adjacent homology domain containing 1,GO:0005677//chromatin silencing complex;GO:0005694//chromosome,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0031507//heterochromatin assembly;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0005515//protein binding,-
22894,0,40,0,66,31,9,46,0,77,0,0,3,DIS3;DIS3 exosome endoribonuclease and 3'-5' exoribonuclease,GO:0005634//nucleus;GO:0000176//nuclear exosome (RNase complex);GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex);GO:0005654//nucleoplasm;GO:0016020//membrane,"GO:0016075//rRNA catabolic process;GO:0043547//positive regulation of GTPase activity;GO:0016070//RNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0016071//mRNA metabolic process;GO:0006364//rRNA processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071034//CUT catabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0000175//3'-5'-exoribonuclease activity;GO:0005515//protein binding;GO:0004519//endonuclease activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0003723//RNA binding,K12585//RNA degradation
22895,75,0,0,0,0,0,0,0,7,265,0,1,RPH3A;rabphilin 3A,GO:0030054//cell junction;GO:0016020//membrane;GO:0008021//synaptic vesicle,GO:0006886//intracellular protein transport,GO:0005544//calcium-dependent phospholipid binding;GO:0017137//Rab GTPase binding;GO:0005215//transporter activity;GO:0005515//protein binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0005509//calcium ion binding,K15290//Synaptic vesicle cycle
22897,0,0,0,0,0,23,0,8,23,0,0,0,CEP164;centrosomal protein 164kDa,GO:0005829//cytosol;GO:0005814//centriole;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0097539//ciliary transition fiber;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0042384//cilium assembly;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,K06102//Tight junction
22898,92,0,0,0,0,32,26,133,55,0,6,0,DENND3;DENN/MADD domain containing 3,-,GO:0008333//endosome to lysosome transport;GO:0044257//cellular protein catabolic process;GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
22899,0,0,0,0,0,34,47,0,13,84,4,0,ARHGEF15;Rho guanine nucleotide exchange factor (GEF) 15,GO:0030425//dendrite;GO:0005737//cytoplasm,GO:2000297//negative regulation of synapse maturation;GO:0032321//positive regulation of Rho GTPase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0050790//regulation of catalytic activity;GO:0061299//retina vasculature morphogenesis in camera-type eye,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005096//GTPase activator activity,K07525//Axon guidance
229,0,0,0,0,17,54,0,0,3,0,2,0,"ALDOB;aldolase B, fructose-bisphosphate",GO:0005815//microtubule organizing center;GO:0034451//centriolar satellite;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0006001//fructose catabolic process;GO:0044281//small molecule metabolic process;GO:0032781//positive regulation of ATPase activity;GO:0005975//carbohydrate metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0006000//fructose metabolic process;GO:0006094//gluconeogenesis;GO:0006116//NADH oxidation;GO:0070072//vacuolar proton-transporting V-type ATPase complex assembly",GO:0070061//fructose binding;GO:0008092//cytoskeletal protein binding;GO:0004332//fructose-bisphosphate aldolase activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0051117//ATPase binding,"K01623//Sulfur metabolism;Fructose and mannose metabolism;Pentose phosphate pathway;Metabolic pathways;Phenylalanine, tyrosine and tryptophan biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Cysteine and methionine metabolism"
2290,35,0,6,0,0,0,15,0,0,0,0,0,FOXG1;forkhead box G1,GO:0005634//nucleus,"GO:0042472//inner ear morphogenesis;GO:0007568//aging;GO:0045787//positive regulation of cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0048664//neuron fate determination;GO:0045665//negative regulation of neuron differentiation;GO:0009953//dorsal/ventral pattern formation;GO:0016199//axon midline choice point recognition;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0002052//positive regulation of neuroblast proliferation;GO:0007420//brain development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
22900,0,1,0,14,26,7,0,0,25,0,0,0,"CARD8;caspase recruitment domain family, member 8",GO:0005730//nucleolus;GO:0072559//NLRP3 inflammasome complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0032089//NACHT domain binding,K12801//NOD-like receptor signaling pathway
22901,0,0,0,0,0,31,41,0,35,0,0,0,ARSG;arylsulfatase G,GO:0005788//endoplasmic reticulum lumen;GO:0005764//lysosome;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space,GO:0006790//sulfur compound metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process,GO:0046872//metal ion binding;GO:0004065//arylsulfatase activity,K12381//Lysosome
22902,14,0,0,20,31,20,16,0,37,11,5,0,RUFY3;RUN and FYVE domain containing 3,GO:0030175//filopodium;GO:0030426//growth cone,GO:0050771//negative regulation of axonogenesis,-,K12482//Endocytosis
22903,155,1,0,19,65,13,0,0,32,36,0,227,BTBD3;BTB (POZ) domain containing 3,GO:0005829//cytosol;GO:0005634//nucleus,GO:0021987//cerebral cortex development;GO:0048813//dendrite morphogenesis,-,-
22904,0,0,0,0,0,35,13,44,25,303,14,0,SBNO2;strawberry notch homolog 2 (Drosophila),-,"GO:0050727//regulation of inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030282//bone mineralization;GO:0002281//macrophage activation involved in immune response;GO:0072675//osteoclast fusion",-,-
22905,0,0,0,0,10,10,0,0,13,0,0,0,EPN2;epsin 2,GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0030128//clathrin coat of endocytic vesicle;GO:0005634//nucleus,GO:0001701//in utero embryonic development;GO:0006897//endocytosis;GO:0048568//embryonic organ development;GO:0007219//Notch signaling pathway,GO:0008289//lipid binding,K12471//Endocytosis
22906,167,0,0,30,138,17,0,3,53,0,26,0,"TRAK1;trafficking protein, kinesin binding 1",GO:0005739//mitochondrion;GO:0005769//early endosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008333//endosome to lysosome transport;GO:0006605//protein targeting;GO:0006493//protein O-linked glycosylation;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0050811//GABA receptor binding;GO:0005515//protein binding,-
22907,19,0,2,0,8,0,40,47,44,0,0,0,DHX30;DEAH (Asp-Glu-Ala-His) box helicase 30,GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0006200//ATP catabolic process,GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
22908,0,0,0,30,79,8,0,0,22,0,1,0,SACM1L;SAC1 suppressor of actin mutations 1-like (yeast),GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane,GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process,GO:0016791//phosphatase activity;GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0005515//protein binding;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0034593//phosphatidylinositol bisphosphate phosphatase activity,K01099//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
22909,0,305,329,312,630,11,0,172,59,1,800,0,FAN1;FANCD2/FANCI-associated nuclease 1,GO:0005634//nucleus,"GO:0006281//DNA repair;GO:0000724//double-strand break repair via homologous recombination;GO:0033683//nucleotide-excision repair, DNA incision;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair",GO:0003677//DNA binding;GO:0017108//5'-flap endonuclease activity;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0043130//ubiquitin binding;GO:0004528//phosphodiesterase I activity;GO:0008409//5'-3' exonuclease activity,K15363//Fanconi anemia pathway
22911,25,0,0,3,9,0,14,145,24,1,0,0,WDR47;WD repeat domain 47,GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007275//multicellular organismal development,-,K04539//Alcoholism;Retrograde endocannabinoid signaling;Serotonergic synapse;Cholinergic synapse;GABAergic synapse;Dopaminergic synapse;Chemokine signaling pathway;Morphine addiction;Glutamatergic synapse;K12857//Spliceosome
22913,0,0,0,0,20,0,34,0,52,1,0,0,RALY;RALY heterogeneous nuclear ribonucleoprotein,GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
22915,0,17,0,0,0,0,0,0,60,0,0,0,MMRN1;multimerin 1,GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region,GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0030168//platelet activation;GO:0007155//cell adhesion,-,K12478//Tuberculosis;Endocytosis;Phagosome
22916,0,1,2,16,87,2,0,0,22,0,0,0,"NCBP2;nuclear cap binding protein subunit 2, 20kDa",GO:0005737//cytoplasm;GO:0005846//nuclear cap binding complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005845//mRNA cap binding complex;GO:0005829//cytosol,"GO:0031047//gene silencing by RNA;GO:0006446//regulation of translational initiation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006406//mRNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process;GO:0046833//positive regulation of RNA export from nucleus;GO:0000387//spliceosomal snRNP assembly;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0045292//mRNA cis splicing, via spliceosome;GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006370//7-methylguanosine mRNA capping;GO:0000398//mRNA splicing, via spliceosome;GO:0034660//ncRNA metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006408//snRNA export from nucleus",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0000339//RNA cap binding;GO:0003723//RNA binding,K12883//Spliceosome;mRNA surveillance pathway;RNA transport
22917,86,0,33,0,0,8,0,0,7,0,31,0,ZP1;zona pellucida glycoprotein 1 (sperm receptor),GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0016021//integral component of membrane;GO:0005578//proteinaceous extracellular matrix,GO:0007339//binding of sperm to zona pellucida;GO:0032504//multicellular organism reproduction;GO:0007338//single fertilization,-,K13912//Salivary secretion
22918,0,0,0,0,0,0,0,0,21,0,0,0,CD93;CD93 molecule,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0006909//phagocytosis;GO:0016032//viral process;GO:0016337//single organismal cell-cell adhesion;GO:0042116//macrophage activation,GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding;GO:0001849//complement component C1q binding;GO:0005515//protein binding;GO:0004872//receptor activity,-
22919,0,41,2,63,175,0,0,0,21,0,0,0,"MAPRE1;microtubule-associated protein, RP/EB family, member 1",GO:0005829//cytosol;GO:0035371//microtubule plus-end;GO:0005874//microtubule;GO:0031253//cell projection membrane;GO:0005881//cytoplasmic microtubule;GO:0005794//Golgi apparatus;GO:0030981//cortical microtubule cytoskeleton;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0008283//cell proliferation;GO:0035372//protein localization to microtubule;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0031115//negative regulation of microtubule polymerization,GO:0008022//protein C-terminus binding;GO:0051010//microtubule plus-end binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
22920,0,0,0,15,19,10,0,1,49,0,0,0,KIFAP3;kinesin-associated protein 3,GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0016939//kinesin II complex;GO:0000794//condensed nuclear chromosome;GO:0005829//cytosol;GO:0030990//intraciliary transport particle;GO:0015630//microtubule cytoskeleton;GO:0005876//spindle microtubule,GO:0007165//signal transduction;GO:0046587//positive regulation of calcium-dependent cell-cell adhesion;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0006461//protein complex assembly;GO:0007018//microtubule-based movement;GO:0007017//microtubule-based process;GO:0043066//negative regulation of apoptotic process;GO:0061024//membrane organization;GO:0008285//negative regulation of cell proliferation;GO:0008104//protein localization;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0019894//kinesin binding;GO:0005515//protein binding,-
22921,0,0,0,0,1,0,12,0,54,0,0,0,MSRB2;methionine sulfoxide reductase B2,GO:0005739//mitochondrion,"GO:0006355//regulation of transcription, DNA-templated;GO:0006979//response to oxidative stress;GO:0030041//actin filament polymerization;GO:0030091//protein repair;GO:0055114//oxidation-reduction process",GO:0003779//actin binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
22924,0,0,0,1,26,7,0,0,34,0,0,0,"MAPRE3;microtubule-associated protein, RP/EB family, member 3",GO:0030496//midbody;GO:0005881//cytoplasmic microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0035371//microtubule plus-end;GO:0015630//microtubule cytoskeleton,"GO:0007067//mitotic nuclear division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity",GO:0005515//protein binding;GO:0008017//microtubule binding,-
22925,27,0,0,0,0,0,6,0,81,0,0,0,"PLA2R1;phospholipase A2 receptor 1, 180kDa",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0001816//cytokine production;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0090399//replicative senescence;GO:1900138//negative regulation of phospholipase A2 activity;GO:0006898//receptor-mediated endocytosis;GO:0090403//oxidative stress-induced premature senescence;GO:0090238//positive regulation of arachidonic acid secretion;GO:0072593//reactive oxygen species metabolic process;GO:1900139//negative regulation of arachidonic acid secretion",GO:0004872//receptor activity;GO:0043274//phospholipase binding;GO:0030246//carbohydrate binding,K06560//Tuberculosis;Phagosome
22926,0,0,0,0,21,23,87,0,59,0,0,0,ATF6;activating transcription factor 6,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane,"GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006351//transcription, DNA-templated;GO:0006457//protein folding;GO:0006950//response to stress;GO:0044267//cellular protein metabolic process;GO:0006990//positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity,K09054//Protein processing in endoplasmic reticulum;Alzheimer's disease
22927,0,42,1,14,55,0,47,103,25,0,21,0,HABP4;hyaluronan binding protein 4,GO:0005737//cytoplasm;GO:0030017//sarcomere;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005576//extracellular region,"GO:0030168//platelet activation;GO:0006355//regulation of transcription, DNA-templated;GO:0071260//cellular response to mechanical stimulus;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0006351//transcription, DNA-templated;GO:0043392//negative regulation of DNA binding",GO:0005515//protein binding,-
22928,0,59,0,20,128,11,0,59,0,0,0,0,SEPHS2;selenophosphate synthetase 2,-,GO:0016310//phosphorylation;GO:0016260//selenocysteine biosynthetic process,"GO:0005524//ATP binding;GO:0004756//selenide, water dikinase activity",K01008//Selenocompound metabolism;Metabolic pathways
22929,0,0,0,23,22,0,56,0,37,0,1,0,SEPHS1;selenophosphate synthetase 1,GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0016310//phosphorylation;GO:0006464//cellular protein modification process,"GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004756//selenide, water dikinase activity;GO:0005525//GTP binding;GO:0005524//ATP binding",K01008//Selenocompound metabolism;Metabolic pathways
22930,0,0,0,37,68,18,6,17,30,0,17,0,RAB3GAP1;RAB3 GTPase activating protein subunit 1 (catalytic),GO:0070062//extracellular vesicular exosome;GO:0071782//endoplasmic reticulum tubular network;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0043010//camera-type eye development;GO:0034389//lipid particle organization;GO:0021854//hypothalamus development;GO:0043087//regulation of GTPase activity;GO:0033126//positive regulation of GTP catabolic process;GO:0007420//brain development;GO:0060325//face morphogenesis;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding,-
22931,0,35,0,151,402,51,0,0,69,0,2,1,"RAB18;RAB18, member RAS oncogene family",GO:0071782//endoplasmic reticulum tubular network;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0071786//endoplasmic reticulum tubular network organization;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0034389//lipid particle organization;GO:0001654//eye development;GO:0007420//brain development;GO:0015031//protein transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0019003//GDP binding,-
22932,0,0,0,8,10,0,0,0,0,0,6,0,POMZP3;POM121 and ZP3 fusion,-,-,-,K14316//RNA transport
22933,75,0,0,0,9,55,21,0,18,0,8,0,SIRT2;sirtuin 2,GO:0043220//Schmidt-Lanterman incisure;GO:0043219//lateral loop;GO:0005634//nucleus;GO:0005677//chromatin silencing complex;GO:0005814//centriole;GO:0043204//perikaryon;GO:0097386//glial cell projection;GO:0030496//midbody;GO:0043209//myelin sheath;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0033270//paranode region of axon;GO:0005720//nuclear heterochromatin;GO:0072686//mitotic spindle;GO:0072687//meiotic spindle;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005819//spindle;GO:0005813//centrosome;GO:0033010//paranodal junction;GO:0044224//juxtaparanode region of axon;GO:0005886//plasma membrane;GO:0005694//chromosome,"GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0043491//protein kinase B signaling;GO:0031641//regulation of myelination;GO:0008285//negative regulation of cell proliferation;GO:0007096//regulation of exit from mitosis;GO:0051775//response to redox state;GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0043388//positive regulation of DNA binding;GO:0071872//cellular response to epinephrine stimulus;GO:1900119//positive regulation of execution phase of apoptosis;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore;GO:0006348//chromatin silencing at telomere;GO:0034599//cellular response to oxidative stress;GO:0051781//positive regulation of cell division;GO:0061433//cellular response to caloric restriction;GO:0071219//cellular response to molecule of bacterial origin;GO:1900425//negative regulation of defense response to bacterium;GO:0016575//histone deacetylation;GO:2000777//positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia;GO:0070933//histone H4 deacetylation;GO:0006914//autophagy;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0071456//cellular response to hypoxia;GO:0070932//histone H3 deacetylation;GO:0006471//protein ADP-ribosylation;GO:0042325//regulation of phosphorylation;GO:0044242//cellular lipid catabolic process;GO:0034983//peptidyl-lysine deacetylation;GO:0022011//myelination in peripheral nervous system;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045843//negative regulation of striated muscle tissue development;GO:0045599//negative regulation of fat cell differentiation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0007126//meiotic nuclear division;GO:0045836//positive regulation of meiosis;GO:0021762//substantia nigra development;GO:0016458//gene silencing;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0007067//mitotic nuclear division;GO:0070446//negative regulation of oligodendrocyte progenitor proliferation;GO:1900195//positive regulation of oocyte maturation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0000183//chromatin silencing at rDNA;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0042177//negative regulation of protein catabolic process;GO:0006476//protein deacetylation;GO:0010507//negative regulation of autophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006342//chromatin silencing;GO:0090042//tubulin deacetylation",GO:0048487//beta-tubulin binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0042826//histone deacetylase binding;GO:0035035//histone acetyltransferase binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0043130//ubiquitin binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0070403//NAD+ binding;GO:0004407//histone deacetylase activity;GO:0042903//tubulin deacetylase activity;GO:0033558//protein deacetylase activity;GO:0003682//chromatin binding,-
22934,0,0,0,0,0,0,0,0,9,43,0,0,RPIA;ribose 5-phosphate isomerase A,GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle,"GO:0019693//ribose phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0006098//pentose-phosphate shunt;GO:0005975//carbohydrate metabolic process",GO:0048029//monosaccharide binding;GO:0004751//ribose-5-phosphate isomerase activity,K01807//Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Metabolic pathways;Pentose phosphate pathway;Microbial metabolism in diverse environments
22936,0,117,2,111,343,29,0,0,38,0,0,1,"ELL2;elongation factor, RNA polymerase II, 2",GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",-,-
22937,0,0,0,0,4,45,20,7,37,0,39,0,SCAP;SREBF chaperone,GO:0043234//protein complex;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0042304//regulation of fatty acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0001666//response to hypoxia;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0032933//SREBP signaling pathway;GO:0032868//response to insulin;GO:0044281//small molecule metabolic process;GO:0007568//aging,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0032403//protein complex binding,K10260//Ubiquitin mediated proteolysis
22938,30,0,29,39,103,0,0,47,30,142,17,0,SNW1;SNW domain containing 1,GO:0005730//nucleolus;GO:0000785//chromatin;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0071146//SMAD3-SMAD4 protein complex;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0008024//positive transcription elongation factor complex b,"GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0048384//retinoic acid receptor signaling pathway;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0010467//gene expression;GO:0016032//viral process;GO:0070564//positive regulation of vitamin D receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050769//positive regulation of neurogenesis;GO:0007219//Notch signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071300//cellular response to retinoic acid;GO:0000398//mRNA splicing, via spliceosome;GO:0043923//positive regulation by host of viral transcription;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0048026//positive regulation of mRNA splicing, via spliceosome",GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0005112//Notch binding;GO:0003714//transcription corepressor activity;GO:0046332//SMAD binding;GO:0042974//retinoic acid receptor binding;GO:0042809//vitamin D receptor binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K06063//Notch signaling pathway;Epstein-Barr virus infection;Spliceosome
2294,0,0,0,0,0,0,9,0,31,0,0,0,FOXF1;forkhead box F1,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003214//cardiac left ventricle morphogenesis;GO:0001763//morphogenesis of a branching structure;GO:0007368//determination of left/right symmetry;GO:0051145//smooth muscle cell differentiation;GO:0060461//right lung morphogenesis;GO:0051150//regulation of smooth muscle cell differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0048617//embryonic foregut morphogenesis;GO:0048613//embryonic ectodermal digestive tract morphogenesis;GO:0007224//smoothened signaling pathway;GO:0060426//lung vasculature development;GO:0071407//cellular response to organic cyclic compound;GO:0016337//single organismal cell-cell adhesion;GO:0003197//endocardial cushion development;GO:0006351//transcription, DNA-templated;GO:0048565//digestive tract development;GO:0007494//midgut development;GO:0007507//heart development;GO:0001568//blood vessel development;GO:0090131//mesenchyme migration;GO:0050728//negative regulation of inflammatory response;GO:0060446//branching involved in open tracheal system development;GO:0030324//lung development;GO:0030323//respiratory tube development;GO:0097070//ductus arteriosus closure;GO:0071345//cellular response to cytokine stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0030335//positive regulation of cell migration;GO:0031016//pancreas development;GO:0060463//lung lobe morphogenesis;GO:0043305//negative regulation of mast cell degranulation;GO:0010811//positive regulation of cell-substrate adhesion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060841//venous blood vessel development;GO:0048371//lateral mesodermal cell differentiation;GO:0048286//lung alveolus development;GO:0001570//vasculogenesis;GO:0001756//somitogenesis;GO:0048557//embryonic digestive tract morphogenesis;GO:0072001//renal system development;GO:0030198//extracellular matrix organization;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0014822//detection of wounding;GO:0072189//ureter development;GO:0060438//trachea development",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding,-
22941,0,17,0,4,40,32,53,10,92,230,0,0,SHANK2;SH3 and multiple ankyrin repeat domains 2,GO:0030054//cell junction;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0005883//neurofilament;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0060170//ciliary membrane;GO:0008328//ionotropic glutamate receptor complex;GO:0014069//postsynaptic density;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment,GO:0060292//long term synaptic depression;GO:0007612//learning;GO:0071625//vocalization behavior;GO:0030534//adult behavior;GO:0060291//long-term synaptic potentiation;GO:0035176//social behavior;GO:0007416//synapse assembly,GO:0035255//ionotropic glutamate receptor binding;GO:0030160//GKAP/Homer scaffold activity;GO:0017124//SH3 domain binding;GO:0005515//protein binding,K15009//Glutamatergic synapse
22943,0,0,0,0,0,2,0,0,0,0,0,0,DKK1;dickkopf WNT signaling pathway inhibitor 1,GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0048642//negative regulation of skeletal muscle tissue development;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0032526//response to retinoic acid;GO:2000726//negative regulation of cardiac muscle cell differentiation;GO:0030900//forebrain development;GO:0060325//face morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001706//endoderm formation;GO:0031333//negative regulation of protein complex assembly;GO:1901296//negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0000904//cell morphogenesis involved in differentiation;GO:0042663//regulation of endodermal cell fate specification;GO:0002090//regulation of receptor internalization;GO:1900116//extracellular negative regulation of signal transduction;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0001942//hair follicle development;GO:0030326//embryonic limb morphogenesis;GO:0001707//mesoderm formation,GO:0050750//low-density lipoprotein particle receptor binding;GO:0048019//receptor antagonist activity;GO:0008083//growth factor activity;GO:0004871//signal transducer activity;GO:0005515//protein binding,K02165//Wnt signaling pathway
22944,1,0,0,0,9,0,0,0,24,0,0,0,"KIN;KIN, antigenic determinant of recA protein homolog (mouse)",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix,GO:0016032//viral process;GO:0006974//cellular response to DNA damage stimulus;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0006397//mRNA processing,GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
22948,0,57,1,78,207,8,0,1,35,0,2,0,"CCT5;chaperonin containing TCP1, subunit 5 (epsilon)",GO:0005874//microtubule;GO:0005829//cytosol;GO:0002199//zona pellucida receptor complex;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005832//chaperonin-containing T-complex;GO:0070062//extracellular vesicular exosome,GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0009615//response to virus;GO:0044267//cellular protein metabolic process,GO:0031681//G-protein beta-subunit binding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding,-
22949,0,206,1,108,715,11,0,0,27,135,0,0,PTGR1;prostaglandin reductase 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:2001300//lipoxin metabolic process;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0009636//response to toxic substance;GO:0019371//cyclooxygenase pathway;GO:0006691//leukotriene metabolic process,GO:0032440//2-alkenal reductase [NAD(P)] activity;GO:0047522//15-oxoprostaglandin 13-oxidase activity;GO:0036132//13-prostaglandin reductase activity;GO:0008270//zinc ion binding,-
2295,0,0,0,0,0,0,9,0,0,0,0,0,FOXF2;forkhead box F2,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0001837//epithelial to mesenchymal transition;GO:0048596//embryonic camera-type eye morphogenesis;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0030198//extracellular matrix organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060021//palate development;GO:0048566//embryonic digestive tract development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0048806//genitalia development",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
22950,0,60,17,53,137,33,75,0,33,0,75,0,"SLC4A1AP;solute carrier family 4 (anion exchanger), member 1, adaptor protein",GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,-
22952,0,0,0,0,5,0,0,0,1,0,0,0,"CYP2G1P;cytochrome P450, family 2, subfamily G, polypeptide 1 pseudogene",-,GO:0055114//oxidation-reduction process,"GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",-
22953,0,0,0,0,0,0,0,0,30,0,0,0,"P2RX2;purinergic receptor P2X, ligand-gated ion channel, 2",GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0043197//dendritic spine;GO:0005639//integral component of nuclear inner membrane;GO:0014069//postsynaptic density;GO:0042734//presynaptic membrane;GO:0009986//cell surface;GO:0043195//terminal bouton;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane,GO:0050909//sensory perception of taste;GO:0001666//response to hypoxia;GO:0034220//ion transmembrane transport;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0009743//response to carbohydrate;GO:0007274//neuromuscular synaptic transmission;GO:0050850//positive regulation of calcium-mediated signaling;GO:0014832//urinary bladder smooth muscle contraction;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0003029//detection of hypoxic conditions in blood by carotid body chemoreceptor signaling;GO:0006812//cation transport;GO:0048266//behavioral response to pain;GO:0019228//neuronal action potential;GO:0030432//peristalsis;GO:0007605//sensory perception of sound;GO:0051260//protein homooligomerization;GO:0048741//skeletal muscle fiber development;GO:0007528//neuromuscular junction development;GO:0033198//response to ATP,GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0045340//mercury ion binding;GO:0001614//purinergic nucleotide receptor activity;GO:0008144//drug binding;GO:0035091//phosphatidylinositol binding;GO:0015276//ligand-gated ion channel activity;GO:0008270//zinc ion binding;GO:0050897//cobalt ion binding;GO:0016151//nickel cation binding;GO:0005507//copper ion binding;GO:0004931//extracellular ATP-gated cation channel activity;GO:0046870//cadmium ion binding,K05216//Neuroactive ligand-receptor interaction;Calcium signaling pathway
22954,0,0,0,0,0,24,0,0,19,0,12,1,TRIM32;tripartite motif containing 32,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005863//striated muscle myosin thick filament;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032481//positive regulation of type I interferon production;GO:0045732//positive regulation of protein catabolic process;GO:2000147//positive regulation of cell motility;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000209//protein polyubiquitination;GO:0009411//response to UV;GO:0030307//positive regulation of cell growth;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:0030335//positive regulation of cell migration;GO:1902187//negative regulation of viral release from host cell;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045787//positive regulation of cell cycle;GO:0045444//fat cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0050769//positive regulation of neurogenesis;GO:0045862//positive regulation of proteolysis;GO:0034612//response to tumor necrosis factor;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0048147//negative regulation of fibroblast proliferation,GO:0003723//RNA binding;GO:0003713//transcription coactivator activity;GO:0031369//translation initiation factor binding;GO:0030957//Tat protein binding;GO:0017022//myosin binding;GO:0016874//ligase activity;GO:0043130//ubiquitin binding;GO:0008270//zinc ion binding;GO:0043621//protein self-association;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10607//Ubiquitin mediated proteolysis
22955,0,0,0,35,90,6,0,0,10,141,1,0,SCMH1;sex comb on midleg homolog 1 (Drosophila),GO:0010369//chromocenter;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0007283//spermatogenesis;GO:0016458//gene silencing;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0006338//chromatin remodeling;GO:0009952//anterior/posterior pattern specification;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2296,0,0,0,0,0,0,0,0,0,44,0,0,FOXC1;forkhead box C1,GO:0005730//nucleolus;GO:0005720//nuclear heterochromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0030203//glycosaminoglycan metabolic process;GO:0048844//artery morphogenesis;GO:0035050//embryonic heart tube development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0060038//cardiac muscle cell proliferation;GO:0001501//skeletal system development;GO:0007507//heart development;GO:0043010//camera-type eye development;GO:0045930//negative regulation of mitotic cell cycle;GO:0007420//brain development;GO:0032808//lacrimal gland development;GO:0001654//eye development;GO:0001945//lymph vessel development;GO:0030199//collagen fibril organization;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0008354//germ cell migration;GO:0001657//ureteric bud development;GO:0007219//Notch signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046620//regulation of organ growth;GO:1902257//negative regulation of apoptotic process involved in outflow tract morphogenesis;GO:0014032//neural crest cell development;GO:0050880//regulation of blood vessel size;GO:0001541//ovarian follicle development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001974//blood vessel remodeling;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0001503//ossification;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0048341//paraxial mesoderm formation","GO:0008301//DNA binding, bending;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding",-
2297,0,0,0,0,0,14,0,0,4,1,12,0,FOXD1;forkhead box D1,GO:0005634//nucleus,"GO:0060678//dichotomous subdivision of terminal units involved in ureteric bud branching;GO:0030513//positive regulation of BMP signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072267//metanephric capsule specification;GO:0072210//metanephric nephron development;GO:0090184//positive regulation of kidney development;GO:0072076//nephrogenic mesenchyme development;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0007411//axon guidance","GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008301//DNA binding, bending;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding",-
22974,0,0,0,0,0,17,0,0,42,0,0,0,"TPX2;TPX2, microtubule-associated",GO:0005819//spindle;GO:0043203//axon hillock;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0000922//spindle pole;GO:0005874//microtubule;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0008283//cell proliferation;GO:0060236//regulation of mitotic spindle organization;GO:0006915//apoptotic process;GO:0032147//activation of protein kinase activity;GO:0007067//mitotic nuclear division,GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
22976,51,235,309,209,435,0,40,211,46,0,352,196,PAXIP1;PAX interacting (with transcription-activation domain) protein 1,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus;GO:0016363//nuclear matrix,"GO:0051571//positive regulation of histone H3-K4 methylation;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006310//DNA recombination;GO:0031398//positive regulation of protein ubiquitination;GO:0043542//endothelial cell migration;GO:0006281//DNA repair;GO:0051568//histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0035066//positive regulation of histone acetylation;GO:0045830//positive regulation of isotype switching;GO:0060612//adipose tissue development;GO:0060717//chorion development;GO:0000416//positive regulation of histone H3-K36 methylation;GO:0001570//vasculogenesis;GO:0010212//response to ionizing radiation",GO:0005515//protein binding,-
22977,0,0,0,0,0,13,63,0,12,0,0,0,"AKR7A3;aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006081//cellular aldehyde metabolic process;GO:0055114//oxidation-reduction process,GO:0009055//electron carrier activity;GO:0004033//aldo-keto reductase (NADP) activity,K15303//Metabolism of xenobiotics by cytochrome P450
22978,1,24,2,46,210,0,1,0,79,0,1,99,"NT5C2;5'-nucleotidase, cytosolic II",GO:0005829//cytosol,GO:0016311//dephosphorylation;GO:0008219//cell death;GO:0017144//drug metabolic process;GO:0016310//phosphorylation;GO:0006195//purine nucleotide catabolic process;GO:0006144//purine nucleobase metabolic process;GO:0044281//small molecule metabolic process,GO:0050146//nucleoside phosphotransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0008253//5'-nucleotidase activity,K01081//Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
22979,164,0,0,0,0,2,0,0,32,0,11,0,EFR3B;EFR3 homolog B (S. cerevisiae),-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2298,0,0,0,0,0,0,3,0,36,0,0,0,FOXD4;forkhead box D4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated","GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0008301//DNA binding, bending",-
22980,67,38,0,13,47,26,0,0,52,28,0,271,TCF25;transcription factor 25 (basic helix-loop-helix),GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
22981,0,2,0,12,28,13,20,0,60,0,3,0,NINL;ninein-like,GO:0005829//cytosol;GO:0005874//microtubule;GO:0005815//microtubule organizing center,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0005509//calcium ion binding,K06102//Tight junction;K12478//Tuberculosis;Phagosome;Endocytosis;K00688//Starch and sucrose metabolism;Insulin signaling pathway
22982,0,1,0,0,13,35,44,0,33,0,8,0,DIP2C;DIP2 disco-interacting protein 2 homolog C (Drosophila),GO:0005634//nucleus,GO:0008152//metabolic process,GO:0008134//transcription factor binding;GO:0003824//catalytic activity,-
22983,81,0,0,0,4,35,0,72,11,2,8,387,MAST1;microtubule associated serine/threonine kinase 1,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane,GO:0007010//cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
22984,54,24,0,0,13,21,127,0,18,0,25,0,PDCD11;programmed cell death 11,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006364//rRNA processing;GO:0006397//mRNA processing,GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
22985,0,15,59,94,221,27,0,1,27,0,89,0,ACIN1;apoptotic chromatin condensation inducer 1,GO:0061574//ASAP complex;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0035145//exon-exon junction complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0045657//positive regulation of monocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0030263//apoptotic chromosome condensation;GO:0006200//ATP catabolic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006915//apoptotic process;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process;GO:0048025//negative regulation of mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0016887//ATPase activity;GO:0019899//enzyme binding;GO:0003676//nucleic acid binding,K12875//mRNA surveillance pathway;RNA transport;Spliceosome
22986,207,0,0,0,0,16,0,0,59,2,1,0,SORCS3;sortilin-related VPS10 domain containing receptor 3,GO:0097481//neuronal postsynaptic density;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007218//neuropeptide signaling pathway;GO:1900452//regulation of long term synaptic depression;GO:0007613//memory;GO:0007612//learning,GO:0008188//neuropeptide receptor activity,K12388//Neurotrophin signaling pathway;Lysosome
22987,0,0,0,1,0,0,0,0,71,10,3,0,SV2C;synaptic vesicle glycoprotein 2C,GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006836//neurotransmitter transport,GO:0022857//transmembrane transporter activity,K06258//ECM-receptor interaction
22989,0,0,51,0,13,57,0,48,99,0,0,0,"MYH15;myosin, heavy chain 15",GO:0030016//myofibril;GO:0032982//myosin filament,GO:0008152//metabolic process,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003774//motor activity,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
2299,1,0,0,0,0,0,0,0,4,0,0,0,FOXI1;forkhead box I1,GO:0005634//nucleus,"GO:0009790//embryo development;GO:0042472//inner ear morphogenesis;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter","GO:0008301//DNA binding, bending;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding",-
22990,75,43,8,20,23,35,74,61,142,0,20,140,PCNX;pecanex homolog (Drosophila),GO:0016021//integral component of membrane,-,-,-
22992,179,46,0,21,49,37,90,56,56,0,0,0,KDM2A;lysine (K)-specific demethylase 2A,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm,"GO:0055114//oxidation-reduction process;GO:0070544//histone H3-K36 demethylation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0045322//unmethylated CpG binding,-
22993,0,117,35,73,105,15,11,111,124,0,73,1,HMGXB3;HMG box domain containing 3,GO:0005634//nucleus,GO:0016310//phosphorylation,GO:0016301//kinase activity;GO:0003677//DNA binding,-
22994,7,0,0,0,0,0,0,46,33,61,0,17,CEP131;centrosomal protein 131kDa,GO:0042995//cell projection;GO:0005813//centrosome;GO:0005814//centriole;GO:0005829//cytosol;GO:0034464//BBSome;GO:0001669//acrosomal vesicle;GO:0034451//centriolar satellite,GO:0090316//positive regulation of intracellular protein transport;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0010824//regulation of centrosome duplication;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0035735//intraciliary transport involved in cilium morphogenesis;GO:0030154//cell differentiation;GO:0008284//positive regulation of cell proliferation,GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
22995,0,0,0,4,0,8,8,0,19,0,10,0,CEP152;centrosomal protein 152kDa,GO:0005813//centrosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0098536//deuterosome;GO:0005730//nucleolus,GO:0051298//centrosome duplication;GO:0098535//de novo centriole assembly;GO:0030030//cell projection organization;GO:0000278//mitotic cell cycle;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle,GO:0019901//protein kinase binding;GO:0005515//protein binding,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
22997,34,0,0,0,0,0,0,0,67,1,18,473,"IGSF9B;immunoglobulin superfamily, member 9B",GO:0043025//neuronal cell body;GO:0060077//inhibitory synapse;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0097151//positive regulation of inhibitory postsynaptic membrane potential;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0019900//kinase binding,K06754//Axon guidance
22998,108,28,23,29,141,0,22,0,80,0,0,0,LIMCH1;LIM and calponin homology domains 1,-,GO:0031032//actomyosin structure organization,GO:0008270//zinc ion binding;GO:0003779//actin binding,K06084//Adherens junction
22999,0,0,0,43,48,73,40,80,131,0,8,0,RIMS1;regulating synaptic membrane exocytosis 1,GO:0048786//presynaptic active zone;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0050790//regulation of catalytic activity;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0006886//intracellular protein transport;GO:0048791//calcium ion-dependent exocytosis of neurotransmitter;GO:0007268//synaptic transmission;GO:0097151//positive regulation of inhibitory postsynaptic membrane potential;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0046903//secretion;GO:0046928//regulation of neurotransmitter secretion;GO:0006461//protein complex assembly;GO:0045055//regulated secretory pathway;GO:0010628//positive regulation of gene expression;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0061025//membrane fusion;GO:0014047//glutamate secretion;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0017156//calcium ion-dependent exocytosis,GO:0017137//Rab GTPase binding;GO:0005083//small GTPase regulator activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044325//ion channel binding,K15291//Retrograde endocannabinoid signaling;Synaptic vesicle cycle
23,0,0,0,0,0,1,0,0,1,0,0,0,"ABCF1;ATP-binding cassette, sub-family F (GCN20), member 1",GO:0005654//nucleoplasm;GO:0042788//polysomal ribosome;GO:0005737//cytoplasm;GO:0005635//nuclear envelope;GO:0016020//membrane;GO:0005840//ribosome,GO:0042254//ribosome biogenesis;GO:0006200//ATP catabolic process;GO:0006412//translation;GO:0006954//inflammatory response;GO:0006413//translational initiation;GO:0045727//positive regulation of translation,"GO:0005524//ATP binding;GO:0043022//ribosome binding;GO:0008494//translation activator activity;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding",-
230,0,0,0,1,9,0,17,0,1,0,0,0,"ALDOC;aldolase C, fructose-bisphosphate",GO:0005856//cytoskeleton;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0030424//axon,"GO:0030855//epithelial cell differentiation;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0010243//response to organonitrogen compound;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0014070//response to organic cyclic compound;GO:0005975//carbohydrate metabolic process;GO:0007568//aging;GO:0006000//fructose metabolic process;GO:0006094//gluconeogenesis;GO:0051290//protein heterotetramerization;GO:0044281//small molecule metabolic process;GO:0051289//protein homotetramerization;GO:0031100//organ regeneration",GO:0005515//protein binding;GO:0004332//fructose-bisphosphate aldolase activity;GO:0008092//cytoskeletal protein binding,"K01623//Metabolic pathways;Pentose phosphate pathway;Fructose and mannose metabolism;Sulfur metabolism;Cysteine and methionine metabolism;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis;Microbial metabolism in diverse environments"
2300,3,0,0,0,0,9,0,43,6,1,0,0,FOXL1;forkhead box L1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0009887//organ morphogenesis;GO:0007275//multicellular organismal development;GO:0030111//regulation of Wnt signaling pathway;GO:0030166//proteoglycan biosynthetic process;GO:0007507//heart development;GO:0006355//regulation of transcription, DNA-templated;GO:0061146//Peyer's patch morphogenesis","GO:0008301//DNA binding, bending;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding",-
23001,91,91,2,29,266,50,38,0,162,271,18,0,WDFY3;WD repeat and FYVE domain containing 3,GO:0034274//Atg12-Atg5-Atg16 complex;GO:0005776//autophagic vacuole;GO:0005635//nuclear envelope;GO:0016605//PML body;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0031965//nuclear membrane;GO:0016234//inclusion body,GO:0035973//aggrephagy;GO:0016239//positive regulation of macroautophagy,"GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0005545//1-phosphatidylinositol binding;GO:0046872//metal ion binding;GO:0005515//protein binding",K12182//Phagosome;Endocytosis
23002,0,0,0,85,152,10,60,0,16,67,0,0,DAAM1;dishevelled associated activator of morphogenesis 1,GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane,GO:0030036//actin cytoskeleton organization,GO:0003779//actin binding;GO:0017048//Rho GTPase binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K04512//Wnt signaling pathway
23005,72,0,0,0,0,0,25,3,66,1,22,0,MAPKBP1;mitogen-activated protein kinase binding protein 1,-,-,-,K01047//Metabolic pathways;Vascular smooth muscle contraction;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;GnRH signaling pathway;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway;K11447//Transcriptional misregulation in cancer;K14555//Ribosome biogenesis in eukaryotes
23007,0,0,0,0,0,0,13,37,128,68,2,0,"PLCH1;phospholipase C, eta 1",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0048015//phosphatidylinositol-mediated signaling;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0016042//lipid catabolic process,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004871//signal transducer activity;GO:0050429//calcium-dependent phospholipase C activity;GO:0005509//calcium ion binding,K05861//Calcium signaling pathway;Inositol phosphate metabolism;Phosphatidylinositol signaling system;Oocyte meiosis;Metabolic pathways
23008,0,56,0,47,43,13,0,0,62,0,8,0,KLHDC10;kelch domain containing 10,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005515//protein binding,K14966//Herpes simplex infection
2301,94,0,0,0,0,29,0,0,30,0,0,1,FOXE3;forkhead box E3,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0050679//positive regulation of epithelial cell proliferation;GO:0043010//camera-type eye development;GO:0048468//cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23011,0,0,1,95,103,5,0,0,0,0,3,0,"RAB21;RAB21, member RAS oncogene family",GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0032154//cleavage furrow;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005925//focal adhesion;GO:0031901//early endosome membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0015031//protein transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0019003//GDP binding,-
23012,0,24,0,35,104,16,45,0,33,0,24,0,STK38L;serine/threonine kinase 38 like,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0016020//membrane,GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0051128//regulation of cellular component organization,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0003779//actin binding,-
23013,146,22,0,10,60,44,29,2,84,58,15,263,SPEN;spen family transcriptional repressor,GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0016032//viral process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0050769//positive regulation of neurogenesis;GO:0007219//Notch signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0003714//transcription corepressor activity;GO:0003697//single-stranded DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23014,0,13,27,28,94,0,28,0,31,0,0,0,FBXO21;F-box protein 21,GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0003677//DNA binding,-
23015,0,0,0,0,0,13,0,0,32,0,0,0,"GOLGA8A;golgin A8 family, member A",GO:0032580//Golgi cisterna membrane,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K10582//Ubiquitin mediated proteolysis;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K06102//Tight junction
23016,7,0,0,16,0,46,0,0,1,0,0,0,EXOSC7;exosome component 7,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0000178//exosome (RNase complex),"GO:0006364//rRNA processing;GO:0006401//RNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0004532//exoribonuclease activity;GO:0003723//RNA binding,K12589//RNA degradation
23017,47,0,0,7,0,18,0,2,54,0,1,0,FAIM2;Fas apoptotic inhibitory molecule 2,GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0043066//negative regulation of apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0002931//response to ischemia;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021680//cerebellar Purkinje cell layer development;GO:0006915//apoptotic process;GO:0021681//cerebellar granular layer development;GO:0043524//negative regulation of neuron apoptotic process;GO:0021549//cerebellum development,-,-
23019,102,160,23,234,342,2,0,96,91,39,117,0,"CNOT1;CCR4-NOT transcription complex, subunit 1",GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0000932//cytoplasmic mRNA processing body;GO:0030014//CCR4-NOT complex,"GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006351//transcription, DNA-templated;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006417//regulation of translation;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0016070//RNA metabolic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0016071//mRNA metabolic process;GO:0001829//trophectodermal cell differentiation;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:2000036//regulation of stem cell maintenance",GO:0030331//estrogen receptor binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0042974//retinoic acid receptor binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12604//RNA degradation
2302,0,0,0,0,0,0,0,0,8,0,8,0,FOXJ1;forkhead box J1,GO:0005634//nucleus,"GO:0072016//glomerular parietal epithelial cell development;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0050900//leukocyte migration;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1901248//positive regulation of lung ciliated cell differentiation;GO:0042384//cilium assembly;GO:0060429//epithelium development;GO:0002897//positive regulation of central B cell tolerance induction;GO:0007283//spermatogenesis;GO:0006959//humoral immune response;GO:0060972//left/right pattern formation;GO:0042130//negative regulation of T cell proliferation;GO:0035089//establishment of apical/basal cell polarity;GO:0035502//metanephric part of ureteric bud development;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0007389//pattern specification process;GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050869//negative regulation of B cell activation;GO:0007420//brain development;GO:0030036//actin cytoskeleton organization;GO:0032862//activation of Rho GTPase activity;GO:0006351//transcription, DNA-templated;GO:0060428//lung epithelium development;GO:0002635//negative regulation of germinal center formation",GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23020,208,50,4,38,116,33,39,0,143,143,18,0,SNRNP200;small nuclear ribonucleoprotein 200kDa (U5),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006200//ATP catabolic process;GO:0001649//osteoblast differentiation;GO:0000354//cis assembly of pre-catalytic spliceosome;GO:0000398//mRNA splicing, via spliceosome",GO:0005524//ATP binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008026//ATP-dependent helicase activity;GO:0042802//identical protein binding,K12854//Spliceosome
23022,0,31,13,0,61,37,0,0,41,0,0,0,"PALLD;palladin, cytoskeletal associated protein",GO:0030027//lamellipodium;GO:0030018//Z disc;GO:0005884//actin filament;GO:0005634//nucleus;GO:0001726//ruffle;GO:0005925//focal adhesion,GO:0007010//cytoskeleton organization,GO:0051371//muscle alpha-actinin binding;GO:0003779//actin binding;GO:0005515//protein binding,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
23023,0,81,2,2,48,18,0,94,93,0,0,0,TMCC1;transmembrane and coiled-coil domain family 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
23024,0,0,26,12,48,31,37,222,14,176,49,111,PDZRN3;PDZ domain containing ring finger 3,GO:0031594//neuromuscular junction,GO:0007528//neuromuscular junction development;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
23025,255,0,0,0,7,12,19,101,150,1,11,0,UNC13A;unc-13 homolog A (C. elegans),GO:0042734//presynaptic membrane;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0030424//axon;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0048786//presynaptic active zone,"GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0016188//synaptic vesicle maturation;GO:0060384//innervation;GO:0035249//synaptic transmission, glutamatergic;GO:0035556//intracellular signal transduction;GO:0007269//neurotransmitter secretion;GO:0050435//beta-amyloid metabolic process;GO:0001956//positive regulation of neurotransmitter secretion;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0007528//neuromuscular junction development;GO:0051966//regulation of synaptic transmission, glutamatergic",GO:0017075//syntaxin-1 binding;GO:0046872//metal ion binding;GO:0047485//protein N-terminus binding;GO:0019992//diacylglycerol binding,K15293//Synaptic vesicle cycle
23026,71,0,0,0,0,25,0,0,58,2,13,0,MYO16;myosin XVI,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0016459//myosin complex;GO:0005654//nucleoplasm,GO:0048812//neuron projection morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0008152//metabolic process;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0021549//cerebellum development,GO:0019903//protein phosphatase binding;GO:0005524//ATP binding;GO:0051015//actin filament binding;GO:0003774//motor activity,K08834//Phototransduction - fly
23028,0,0,0,37,135,0,19,0,32,0,20,0,KDM1A;lysine (K)-specific demethylase 1A,GO:0005730//nucleolus;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001701//in utero embryonic development;GO:0021983//pituitary gland development;GO:0006482//protein demethylation;GO:2000648//positive regulation of stem cell proliferation;GO:0006351//transcription, DNA-templated;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0008283//cell proliferation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0046886//positive regulation of hormone biosynthetic process;GO:0032091//negative regulation of protein binding;GO:0030851//granulocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034720//histone H3-K4 demethylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010725//regulation of primitive erythrocyte differentiation;GO:0033169//histone H3-K9 demethylation;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0055001//muscle cell development;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0055114//oxidation-reduction process;GO:0007596//blood coagulation;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0051573//negative regulation of histone H3-K9 methylation",GO:0050660//flavin adenine dinucleotide binding;GO:0005515//protein binding;GO:0032454//histone demethylase activity (H3-K9 specific);GO:0008134//transcription factor binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0016491//oxidoreductase activity;GO:0032451//demethylase activity;GO:0034648//histone demethylase activity (H3-dimethyl-K4 specific);GO:0050681//androgen receptor binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0002039//p53 binding;GO:0032452//histone demethylase activity;GO:0043426//MRF binding,-
23029,0,0,20,0,19,1,0,0,29,0,0,0,RBM34;RNA binding motif protein 34,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
2303,0,0,0,0,11,0,0,0,1,0,5,0,"FOXC2;forkhead box C2 (MFH-1, mesenchyme forkhead 1)",GO:0005634//nucleus,"GO:0048343//paraxial mesodermal cell fate commitment;GO:0008286//insulin receptor signaling pathway;GO:0072144//glomerular mesangial cell development;GO:0072011//glomerular endothelium development;GO:0048844//artery morphogenesis;GO:0001569//patterning of blood vessels;GO:0001946//lymphangiogenesis;GO:0035050//embryonic heart tube development;GO:0060038//cardiac muscle cell proliferation;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0010595//positive regulation of endothelial cell migration;GO:0048703//embryonic viscerocranium morphogenesis;GO:0030199//collagen fibril organization;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0043010//camera-type eye development;GO:0035470//positive regulation of vascular wound healing;GO:0007507//heart development;GO:0046620//regulation of organ growth;GO:1902257//negative regulation of apoptotic process involved in outflow tract morphogenesis;GO:0014032//neural crest cell development;GO:0050880//regulation of blood vessel size;GO:0006366//transcription from RNA polymerase II promoter;GO:0009725//response to hormone;GO:0001657//ureteric bud development;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0007219//Notch signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0001656//metanephros development;GO:0001974//blood vessel remodeling;GO:0001756//somitogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001503//ossification",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding,-
23030,0,16,0,6,36,0,0,1,0,0,11,0,KDM4B;lysine (K)-specific demethylase 4B,GO:0005925//focal adhesion;GO:0030054//cell junction;GO:0005634//nucleus,"GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0055114//oxidation-reduction process",GO:0051213//dioxygenase activity;GO:0008270//zinc ion binding,-
23031,268,0,0,0,0,50,17,107,42,51,6,1,MAST3;microtubule associated serine/threonine kinase 3,-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
23032,82,2,1,57,122,0,0,121,21,0,0,1,USP33;ubiquitin specific peptidase 33,GO:0030891//VCB complex;GO:0005794//Golgi apparatus;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0048471//perinuclear region of cytoplasm,GO:0007411//axon guidance;GO:0006897//endocytosis;GO:0071108//protein K48-linked deubiquitination;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0070536//protein K63-linked deubiquitination;GO:0016579//protein deubiquitination;GO:0051298//centrosome duplication;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016477//cell migration,GO:0008270//zinc ion binding;GO:0004843//ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0001664//G-protein coupled receptor binding;GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity,-
23033,129,443,340,767,847,0,32,315,129,0,904,1,DOPEY1;dopey family member 1,-,GO:0015031//protein transport,-,-
23034,0,0,0,4,1,9,0,74,114,0,0,0,SAMD4A;sterile alpha motif domain containing 4A,GO:0005737//cytoplasm;GO:0045202//synapse;GO:0030054//cell junction;GO:0030425//dendrite,GO:0017148//negative regulation of translation;GO:0045727//positive regulation of translation,GO:0030371//translation repressor activity;GO:0044822//poly(A) RNA binding,-
23035,1,0,0,0,9,17,0,75,118,0,0,107,PHLPP2;PH domain and leucine rich repeat protein phosphatase 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0001917//photoreceptor inner segment;GO:0042622//photoreceptor outer segment membrane;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006470//protein dephosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0004722//protein serine/threonine phosphatase activity;GO:0046872//metal ion binding,-
23036,0,0,1,25,102,0,0,0,97,0,16,1,ZNF292;zinc finger protein 292,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
23037,0,0,44,2,1,39,112,8,30,157,26,302,PDZD2;PDZ domain containing 2,GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region,GO:0007155//cell adhesion,-,K06095//Tight junction
23038,91,0,0,10,41,5,17,1,38,0,20,0,WDTC1;WD and tetratricopeptide repeats 1,GO:0005829//cytosol;GO:0005634//nucleus,GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043086//negative regulation of catalytic activity;GO:0035264//multicellular organism growth;GO:0032869//cellular response to insulin stimulus;GO:0055082//cellular chemical homeostasis;GO:0006006//glucose metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0001701//in utero embryonic development;GO:0008361//regulation of cell size,GO:0005515//protein binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0004857//enzyme inhibitor activity,-
23039,0,39,0,26,98,0,17,0,18,0,8,0,XPO7;exportin 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005643//nuclear pore,GO:0051028//mRNA transport;GO:0006611//protein export from nucleus,GO:0008536//Ran GTPase binding;GO:0005049//nuclear export signal receptor activity,K05189//GABAergic synapse;Morphine addiction;Nicotine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
2304,0,0,0,0,0,15,1,0,0,0,3,0,FOXE1;forkhead box E1 (thyroid transcription factor 2),GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0031069//hair follicle morphogenesis;GO:0048538//thymus development;GO:0060465//pharynx development;GO:0030878//thyroid gland development;GO:0048562//embryonic organ morphogenesis;GO:0016477//cell migration;GO:0006590//thyroid hormone generation;GO:0060022//hard palate development;GO:0009653//anatomical structure morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0060023//soft palate development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003690//double-stranded DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
23040,0,0,25,0,0,20,20,0,38,0,2,0,MYT1L;myelin transcription factor 1-like,GO:0005634//nucleus,"GO:0007399//nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
23041,0,0,0,23,8,76,32,0,129,0,20,0,MON2;MON2 homolog (S. cerevisiae),GO:0070062//extracellular vesicular exosome;GO:0005802//trans-Golgi network,GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport;GO:0006895//Golgi to endosome transport;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization,GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
23042,0,501,118,718,1627,13,2,0,52,0,473,171,PDXDC1;pyridoxal-dependent decarboxylase domain containing 1,GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle,GO:0019752//carboxylic acid metabolic process,GO:0016831//carboxy-lyase activity;GO:0030170//pyridoxal phosphate binding,"K01590//Biosynthesis of secondary metabolites;Metabolic pathways;Histidine metabolism;K01580//Alanine, aspartate and glutamate metabolism;Metabolic pathways;beta-Alanine metabolism;Biosynthesis of secondary metabolites;Taurine and hypotaurine metabolism;Type I diabetes mellitus;GABAergic synapse;Butanoate metabolism"
23043,77,0,0,0,0,10,0,25,96,0,4,0,TNIK;TRAF2 and NCK interacting kinase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0055037//recycling endosome;GO:0070062//extracellular vesicular exosome,GO:0016055//Wnt signaling pathway;GO:0046777//protein autophosphorylation;GO:0048814//regulation of dendrite morphogenesis;GO:0031532//actin cytoskeleton reorganization;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0007256//activation of JNKK activity,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005083//small GTPase regulator activity;GO:0005524//ATP binding,-
23046,0,0,21,1,0,22,19,60,46,0,26,616,KIF21B;kinesin family member 21B,GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
23047,0,13,0,11,73,59,5,0,96,0,7,0,"PDS5B;PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)","GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005694//chromosome;GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus",GO:0000278//mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0042127//regulation of cell proliferation;GO:0008283//cell proliferation;GO:0007064//mitotic sister chromatid cohesion,GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
23048,0,0,0,33,71,0,56,1,111,8,1,0,FNBP1;formin binding protein 1,GO:0005764//lysosome;GO:0005905//coated pit;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0006897//endocytosis,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008289//lipid binding,K07196//Insulin signaling pathway
23049,0,42,49,28,171,38,57,75,190,257,12,0,SMG1;SMG1 phosphatidylinositol 3-kinase-related kinase,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0046854//phosphatidylinositol phosphorylation;GO:0010467//gene expression;GO:0006950//response to stress;GO:0006406//mRNA export from nucleus;GO:0018105//peptidyl-serine phosphorylation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0046777//protein autophosphorylation;GO:0006281//DNA repair;GO:0016071//mRNA metabolic process",GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004674//protein serine/threonine kinase activity,K08873//mRNA surveillance pathway
2305,0,0,0,0,0,30,0,56,45,0,0,0,FOXM1;forkhead box M1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:2000781//positive regulation of double-strand break repair;GO:0006281//DNA repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0000278//mitotic cell cycle;GO:0071156//regulation of cell cycle arrest;GO:0000086//G2/M transition of mitotic cell cycle;GO:0090344//negative regulation of cell aging;GO:0001558//regulation of cell growth;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0046578//regulation of Ras protein signal transduction;GO:0007049//cell cycle;GO:0001889//liver development;GO:0006355//regulation of transcription, DNA-templated;GO:0001570//vasculogenesis;GO:0006351//transcription, DNA-templated;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0051726//regulation of cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
23051,0,0,0,14,27,0,0,0,71,0,0,1,ZHX3;zinc fingers and homeoboxes 3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,K11447//Transcriptional misregulation in cancer;K09254//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
23052,0,0,1,0,15,0,0,62,13,0,11,604,ENDOD1;endonuclease domain containing 1,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004519//endonuclease activity;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
23053,1,0,21,20,35,10,45,113,40,0,35,680,"ZSWIM8;zinc finger, SWIM-type containing 8",-,-,GO:0008270//zinc ion binding,-
23054,0,20,0,11,25,12,82,0,12,91,10,30,NCOA6;nuclear receptor coactivator 6,GO:0005634//nucleus;GO:0035097//histone methyltransferase complex;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,"GO:0007420//brain development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0060716//labyrinthine layer blood vessel development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007507//heart development;GO:0044281//small molecule metabolic process;GO:0006352//DNA-templated transcription, initiation;GO:0044255//cellular lipid metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006260//DNA replication;GO:0042921//glucocorticoid receptor signaling pathway;GO:0006281//DNA repair;GO:0030099//myeloid cell differentiation;GO:0009725//response to hormone;GO:0006310//DNA recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0030331//estrogen receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0046966//thyroid hormone receptor binding;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0046965//retinoid X receptor binding,-
23057,0,80,1,3,16,13,0,0,47,0,13,297,NMNAT2;nicotinamide nucleotide adenylyltransferase 2,GO:0005770//late endosome;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0045202//synapse;GO:0005802//trans-Golgi network,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process;GO:0006766//vitamin metabolic process,GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0005524//ATP binding,K06210//Nicotinate and nicotinamide metabolism;Metabolic pathways
23059,0,20,0,8,10,0,0,0,0,0,5,0,CLUAP1;clusterin associated protein 1,GO:0005813//centrosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0043231//intracellular membrane-bounded organelle,GO:0042384//cilium assembly,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K14721//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Cytosolic DNA-sensing pathway
2306,0,0,0,0,12,0,0,0,2,0,0,538,FOXD2;forkhead box D2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23060,0,38,1,28,51,10,18,0,56,0,10,88,ZNF609;zinc finger protein 609,GO:0005634//nucleus,-,GO:0046872//metal ion binding,K10847//Nucleotide excision repair
23061,76,1,0,28,60,0,0,63,32,0,23,0,"TBC1D9B;TBC1 domain family, member 9B (with GRAM domain)",GO:0016021//integral component of membrane,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity;GO:0005509//calcium ion binding,-
23062,81,0,3,47,8,43,53,0,4,16,0,0,"GGA2;golgi-associated, gamma adaptin ear containing, ARF binding protein 2",GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0005794//Golgi apparatus;GO:0030131//clathrin adaptor complex;GO:0005802//trans-Golgi network,GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport,GO:0030306//ADP-ribosylation factor binding;GO:0005515//protein binding,K12404//Lysosome
23063,0,12,0,31,105,0,0,0,90,72,9,0,WAPAL;wings apart-like homolog (Drosophila),"GO:0005730//nucleolus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0000795//synaptonemal complex;GO:0000775//chromosome, centromeric region;GO:0000785//chromatin;GO:0015630//microtubule cytoskeleton;GO:0005694//chromosome;GO:0008278//cohesin complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm",GO:0071922//regulation of cohesin localization to chromatin;GO:0009636//response to toxic substance;GO:0035562//negative regulation of chromatin binding;GO:0008156//negative regulation of DNA replication;GO:0007067//mitotic nuclear division;GO:0016032//viral process;GO:0060623//regulation of chromosome condensation;GO:0000278//mitotic cell cycle;GO:0048146//positive regulation of fibroblast proliferation;GO:0045875//negative regulation of sister chromatid cohesion;GO:0071168//protein localization to chromatin,GO:0005515//protein binding,-
23064,176,115,0,67,200,30,56,0,58,34,0,1,SETX;senataxin,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0007623//circadian rhythm;GO:0006302//double-strand break repair;GO:0032508//DNA duplex unwinding;GO:0006369//termination of RNA polymerase II transcription;GO:0006396//RNA processing;GO:0008219//cell death,GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0003677//DNA binding,-
23065,0,45,32,31,34,13,0,161,39,147,19,0,EMC1;ER membrane protein complex subunit 1,GO:0016021//integral component of membrane;GO:0072546//ER membrane protein complex,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
23066,64,0,0,16,19,35,0,73,36,0,33,0,CAND2;cullin-associated and neddylation-dissociated 2 (putative),GO:0005634//nucleus;GO:0005622//intracellular,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0017025//TBP-class protein binding,-
23067,101,0,0,0,24,4,0,9,45,231,1,0,SETD1B;SET domain containing 1B,GO:0005730//nucleolus;GO:0005694//chromosome;GO:0016607//nuclear speck;GO:0035097//histone methyltransferase complex;GO:0005634//nucleus;GO:0048188//Set1C/COMPASS complex,"GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0006355//regulation of transcription, DNA-templated",GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K11422//Lysine degradation
2307,0,0,0,0,0,29,0,0,3,0,0,0,FOXS1;forkhead box S1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0040018//positive regulation of multicellular organism growth;GO:0001568//blood vessel development;GO:0050885//neuromuscular process controlling balance",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,-
23070,0,0,0,10,1,7,0,60,61,157,17,0,CMTR1;cap methyltransferase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006370//7-methylguanosine mRNA capping;GO:0080009//mRNA methylation;GO:0097309//cap1 mRNA methylation,GO:0003676//nucleic acid binding;GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity,-
23071,0,13,0,21,44,8,0,0,60,0,0,0,ERP44;endoplasmic reticulum protein 44,GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0034976//response to endoplasmic reticulum stress;GO:0009100//glycoprotein metabolic process;GO:0006986//response to unfolded protein;GO:0006457//protein folding;GO:0045454//cell redox homeostasis,GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K09582//Vibrio cholerae infection;Protein processing in endoplasmic reticulum
23072,64,0,0,0,40,0,0,62,64,1,10,1,"HECW1;HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1",GO:0005737//cytoplasm,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
23074,2,33,0,34,181,53,21,68,55,0,18,0,UHRF1BP1L;UHRF1 binding protein 1-like,-,-,-,-
23075,0,0,0,0,22,0,0,0,0,0,0,0,SWAP70;SWAP switching B-cell complex 70kDa subunit,GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045190//isotype switching,GO:0003677//DNA binding;GO:0005509//calcium ion binding;GO:0005524//ATP binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
23076,143,33,1,15,0,39,40,27,44,0,0,1,RRP1B;ribosomal RNA processing 1B,"GO:0005634//nucleus;GO:0000792//heterochromatin;GO:0000791//euchromatin;GO:0005829//cytosol;GO:0030688//preribosome, small subunit precursor;GO:0005730//nucleolus",GO:0010923//negative regulation of phosphatase activity;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
23077,0,150,46,115,328,108,45,49,180,0,0,0,"MYCBP2;MYC binding protein 2, E3 ubiquitin protein ligase",GO:0030424//axon;GO:0016020//membrane;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton,"GO:0051493//regulation of cytoskeleton organization;GO:0032880//regulation of protein localization;GO:0021785//branchiomotor neuron axon guidance;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0042177//negative regulation of protein catabolic process;GO:0021952//central nervous system projection neuron axonogenesis",GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
23078,31,0,60,17,65,65,85,0,90,32,15,0,VWA8;von Willebrand factor A domain containing 8,GO:0005576//extracellular region;GO:0005739//mitochondrion,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity,K14572//Ribosome biogenesis in eukaryotes
2308,0,0,0,20,47,0,0,108,16,0,0,0,FOXO1;forkhead box O1,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0042127//regulation of cell proliferation;GO:0031018//endocrine pancreas development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034599//cellular response to oxidative stress;GO:0009267//cellular response to starvation;GO:0006914//autophagy;GO:0008286//insulin receptor signaling pathway;GO:0006473//protein acetylation;GO:0045087//innate immune response;GO:0001568//blood vessel development;GO:0032869//cellular response to insulin stimulus;GO:0006351//transcription, DNA-templated;GO:0070417//cellular response to cold;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0071732//cellular response to nitric oxide;GO:2000505//regulation of energy homeostasis;GO:0006974//cellular response to DNA damage stimulus;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001678//cellular glucose homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0045722//positive regulation of gluconeogenesis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010508//positive regulation of autophagy;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0071455//cellular response to hyperoxia;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0045599//negative regulation of fat cell differentiation;GO:0035947//regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter;GO:0001659//temperature homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0000989//transcription factor binding transcription factor activity;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0051721//protein phosphatase 2A binding,K07201//Pathways in cancer;Insulin signaling pathway;Transcriptional misregulation in cancer;Prostate cancer
23080,0,51,1,67,266,12,0,0,63,1,16,0,AVL9;AVL9 homolog (S. cerevisiase),GO:0055037//recycling endosome;GO:0016021//integral component of membrane,GO:0016477//cell migration,-,-
23081,0,0,0,6,25,9,25,1,45,0,2,0,KDM4C;lysine (K)-specific demethylase 4C,GO:0000790//nuclear chromatin,"GO:0006351//transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0055114//oxidation-reduction process;GO:0033169//histone H3-K9 demethylation;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0019899//enzyme binding;GO:0008270//zinc ion binding;GO:0051213//dioxygenase activity;GO:0032454//histone demethylase activity (H3-K9 specific);GO:0050681//androgen receptor binding,-
23082,0,0,0,7,13,0,4,59,23,0,0,0,"PPRC1;peroxisome proliferator-activated receptor gamma, coactivator-related 1",GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K07202//Insulin signaling pathway;Huntington's disease;Adipocytokine signaling pathway
23085,0,29,0,0,0,0,0,0,0,0,0,0,ERC1;ELKS/RAB6-interacting/CAST family member 1,GO:0042734//presynaptic membrane;GO:0000139//Golgi membrane;GO:0008385//IkappaB kinase complex;GO:0005737//cytoplasm,"GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0006355//regulation of transcription, DNA-templated;GO:0007252//I-kappaB phosphorylation;GO:0015031//protein transport;GO:0007275//multicellular organismal development",GO:0043522//leucine zipper domain binding;GO:0005515//protein binding;GO:0017137//Rab GTPase binding,K16072//NF-kappa B signaling pathway
23086,0,35,2,133,440,0,3,0,136,0,12,0,EXPH5;exophilin 5,GO:0005768//endosome,GO:0003334//keratinocyte development;GO:0050714//positive regulation of protein secretion;GO:0006886//intracellular protein transport;GO:0045921//positive regulation of exocytosis;GO:0071985//multivesicular body sorting pathway,GO:0017137//Rab GTPase binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
23087,0,1,0,7,11,0,47,0,25,0,16,0,TRIM35;tripartite motif containing 35,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043065//positive regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:1902187//negative regulation of viral release from host cell;GO:0045087//innate immune response;GO:0045930//negative regulation of mitotic cell cycle;GO:0006915//apoptotic process,GO:0008270//zinc ion binding,-
23089,0,58,0,0,50,3,0,7,0,0,1,0,PEG10;paternally expressed 10,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030154//cell differentiation;GO:0001890//placenta development,GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K04303//Neuroactive ligand-receptor interaction;Renin-angiotensin system;K04389//African trypanosomiasis;Influenza A;Type I diabetes mellitus;Pathways in cancer;Chagas disease (American trypanosomiasis);Autoimmune thyroid disease;Measles;Apoptosis;Graft-versus-host disease;Herpes simplex infection;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Neurotrophin signaling pathway;Allograft rejection;Cytokine-cytokine receptor interaction
2309,22,6,0,29,191,0,0,0,34,0,0,0,FOXO3;forkhead box O3,GO:0005829//cytosol;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0048015//phosphatidylinositol-mediated signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006417//regulation of translation;GO:0006351//transcription, DNA-templated;GO:0045648//positive regulation of erythrocyte differentiation;GO:0043525//positive regulation of neuron apoptotic process;GO:0001556//oocyte maturation;GO:0001547//antral ovarian follicle growth;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0001544//initiation of primordial ovarian follicle growth;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001542//ovulation from ovarian follicle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034599//cellular response to oxidative stress;GO:0007173//epidermal growth factor receptor signaling pathway",GO:0001047//core promoter binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0019901//protein kinase binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K09408//Chemokine signaling pathway;Endometrial cancer;Non-small cell lung cancer;Neurotrophin signaling pathway
23090,0,0,0,0,4,0,0,0,34,0,0,0,ZNF423;zinc finger protein 423,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0030513//positive regulation of BMP signaling pathway;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007399//nervous system development;GO:0007219//Notch signaling pathway",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
23091,18,26,58,47,70,0,1,0,32,0,7,0,ZC3H13;zinc finger CCCH-type containing 13,-,-,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
23092,0,0,0,0,16,35,0,0,36,0,0,0,ARHGAP26;Rho GTPase activating protein 26,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005856//cytoskeleton,GO:0007264//small GTPase mediated signal transduction;GO:0030036//actin cytoskeleton organization;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007399//nervous system development;GO:0046847//filopodium assembly,GO:0008093//cytoskeletal adaptor activity;GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity;GO:0005543//phospholipid binding;GO:0017124//SH3 domain binding,K13736//Bacterial invasion of epithelial cells
23093,0,88,45,66,88,0,87,0,50,0,72,0,"TTLL5;tubulin tyrosine ligase-like family, member 5",GO:0005929//cilium;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,"GO:0009566//fertilization;GO:0018095//protein polyglutamylation;GO:0030317//sperm motility;GO:0007288//sperm axoneme assembly;GO:0006351//transcription, DNA-templated",GO:0016874//ligase activity,"K00273//D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Peroxisome;Glycine, serine and threonine metabolism;Penicillin and cephalosporin biosynthesis;Metabolic pathways"
23094,2,34,0,1,34,25,12,0,57,0,6,893,SIPA1L3;signal-induced proliferation-associated 1 like 3,GO:0005615//extracellular space,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0002244//hematopoietic progenitor cell differentiation,GO:0005096//GTPase activator activity,K08013//Leukocyte transendothelial migration
23095,0,58,27,18,173,9,120,94,99,0,0,0,KIF1B;kinesin family member 1B,GO:0005874//microtubule;GO:0031410//cytoplasmic vesicle;GO:0043005//neuron projection;GO:0030659//cytoplasmic vesicle membrane;GO:0005871//kinesin complex;GO:0005739//mitochondrion;GO:0005875//microtubule associated complex,GO:0047497//mitochondrion transport along microtubule;GO:0007270//neuron-neuron synaptic transmission;GO:0006915//apoptotic process;GO:0008089//anterograde axon cargo transport;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0007274//neuromuscular synaptic transmission;GO:0016192//vesicle-mediated transport;GO:0030705//cytoskeleton-dependent intracellular transport,GO:0016887//ATPase activity;GO:0019894//kinesin binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003777//microtubule motor activity;GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding,-
23096,118,0,0,0,0,4,29,0,40,103,4,0,IQSEC2;IQ motif and Sec7 domain 2,GO:0030054//cell junction;GO:0005802//trans-Golgi network;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0016192//vesicle-mediated transport;GO:0032012//regulation of ARF protein signal transduction,GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
23098,175,120,43,31,65,0,7,309,25,0,146,4,SARM1;sterile alpha and TIR motif containing 1,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030424//axon;GO:0005874//microtubule;GO:0030425//dendrite;GO:0030054//cell junction;GO:0045202//synapse;GO:0005737//cytoplasm;GO:0031315//extrinsic component of mitochondrial outer membrane,GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0009749//response to glucose;GO:1901214//regulation of neuron death;GO:0034142//toll-like receptor 4 signaling pathway;GO:0048814//regulation of dendrite morphogenesis;GO:0002224//toll-like receptor signaling pathway,-,K14613//Mineral absorption;Vitamin digestion and absorption
23099,0,0,0,3,14,0,0,0,12,0,0,0,ZBTB43;zinc finger and BTB domain containing 43,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
231,0,6,0,0,17,0,1,0,0,0,30,0,"AKR1B1;aldo-keto reductase family 1, member B1 (aldose reductase)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0006950//response to stress;GO:0055114//oxidation-reduction process;GO:0044597//daunorubicin metabolic process;GO:0008202//steroid metabolic process;GO:0044281//small molecule metabolic process;GO:0044598//doxorubicin metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006700//C21-steroid hormone biosynthetic process,GO:0004033//aldo-keto reductase (NADP) activity;GO:0043795//glyceraldehyde oxidoreductase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0009055//electron carrier activity,K00011//Glycerolipid metabolism;Fructose and mannose metabolism;Galactose metabolism;Pyruvate metabolism;Pentose and glucuronate interconversions;Metabolic pathways
2310,0,0,0,0,1,23,0,0,89,0,0,0,FOXO3B;forkhead box O3B pseudogene,-,-,-,K09408//Neurotrophin signaling pathway;Chemokine signaling pathway;Non-small cell lung cancer;Endometrial cancer
23101,0,0,0,5,0,0,30,128,38,0,16,0,MCF2L2;MCF.2 cell line derived transforming sequence-like 2,-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
23102,0,2,0,0,19,1,25,2,24,0,0,0,"TBC1D2B;TBC1 domain family, member 2B",-,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity;GO:0005515//protein binding,-
23105,0,0,0,0,0,36,68,1,76,274,19,0,FSTL4;follistatin-like 4,GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,K06755//Axon guidance;K06766//Cell adhesion molecules (CAMs);K06754//Axon guidance;K06491//Prion diseases;Cell adhesion molecules (CAMs)
23107,0,1,0,36,56,28,14,0,8,0,0,0,MRPS27;mitochondrial ribosomal protein S27,GO:0005840//ribosome;GO:0005739//mitochondrion,-,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
23108,113,0,2,18,2,65,11,5,28,130,32,296,RAP1GAP2;RAP1 GTPase activating protein 2,GO:0031965//nuclear membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0043005//neuron projection,GO:0010977//negative regulation of neuron projection development;GO:0032854//positive regulation of Rap GTPase activity,GO:0046582//Rap GTPase activator activity,K08013//Leukocyte transendothelial migration
23109,0,0,0,0,0,0,0,0,7,0,2,231,DDN;dendrin,GO:0032591//dendritic spine membrane;GO:0043204//perikaryon;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0042995//cell projection;GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
23111,0,0,0,10,52,0,24,0,44,0,7,0,SPG20;spastic paraplegia 20 (Troyer syndrome),GO:0045202//synapse;GO:0005741//mitochondrial outer membrane;GO:0030496//midbody;GO:0005886//plasma membrane;GO:0005811//lipid particle;GO:0005737//cytoplasm,GO:0034389//lipid particle organization;GO:0050905//neuromuscular process;GO:0051881//regulation of mitochondrial membrane potential;GO:0048698//negative regulation of collateral sprouting in absence of injury;GO:0060612//adipose tissue development;GO:0008219//cell death;GO:0051301//cell division;GO:0030514//negative regulation of BMP signaling pathway;GO:0009838//abscission,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,-
23112,0,67,1,70,222,52,55,39,86,0,12,0,TNRC6B;trinucleotide repeat containing 6B,GO:0005829//cytosol;GO:0000932//cytoplasmic mRNA processing body,"GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0031047//gene silencing by RNA;GO:0007219//Notch signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006417//regulation of translation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010467//gene expression",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,"K11447//Transcriptional misregulation in cancer;K01756//Biosynthesis of secondary metabolites;Mismatch repair;Ribosome;Phenylalanine, tyrosine and tryptophan biosynthesis;Purine metabolism;Flagellar assembly;Alanine, aspartate and glutamate metabolism;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis"
23113,80,0,0,0,0,0,100,50,61,62,33,0,CUL9;cullin 9,GO:0005737//cytoplasm;GO:0031461//cullin-RING ubiquitin ligase complex,GO:0007088//regulation of mitosis;GO:0000226//microtubule cytoskeleton organization;GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding,-
23114,0,0,0,0,0,61,7,0,26,154,6,0,NFASC;neurofascin,GO:0043194//axon initial segment;GO:0005622//intracellular;GO:0005925//focal adhesion;GO:0016021//integral component of membrane;GO:0033010//paranodal junction;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0033268//node of Ranvier;GO:0033270//paranode region of axon,GO:0042552//myelination;GO:0007422//peripheral nervous system development;GO:0019226//transmission of nerve impulse;GO:0034113//heterotypic cell-cell adhesion;GO:0002175//protein localization to paranode region of axon;GO:0050808//synapse organization;GO:0007411//axon guidance;GO:0030913//paranodal junction assembly;GO:0045162//clustering of voltage-gated sodium channels;GO:0071205//protein localization to juxtaparanode region of axon,GO:0005515//protein binding;GO:0086080//protein binding involved in heterotypic cell-cell adhesion,K06757//Cell adhesion molecules (CAMs)
23116,0,81,0,29,1,0,28,126,35,0,5,1,"FAM179B;family with sequence similarity 179, member B",-,-,-,-
23117,0,4,0,0,0,1,0,1,3,0,0,0,"NPIPB3;nuclear pore complex interacting protein family, member B3",GO:0016021//integral component of membrane,-,-,K10413//Vasopressin-regulated water reabsorption;Phagosome;Salmonella infection;K01896//Butanoate metabolism;Metabolic pathways;Lipoic acid metabolism
23118,0,46,1,76,208,0,51,31,59,0,0,0,TAB2;TGF-beta activated kinase 1/MAP3K7 binding protein 2,GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,"GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007507//heart development;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0034138//toll-like receptor 3 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway",GO:0070530//K63-linked polyubiquitin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K04404//Osteoclast differentiation;Leishmaniasis;Toxoplasmosis;Herpes simplex infection;MAPK signaling pathway;Measles;Epstein-Barr virus infection;NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway
23119,107,0,0,0,0,12,0,43,27,0,0,0,HIC2;hypermethylated in cancer 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008022//protein C-terminus binding,-
2312,0,433,248,144,130,16,187,1154,354,47,167,2,FLG;filaggrin,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005882//intermediate filament;GO:0005634//nucleus,GO:0030216//keratinocyte differentiation;GO:0061436//establishment of skin barrier;GO:0007275//multicellular organismal development,GO:0005198//structural molecule activity;GO:0005509//calcium ion binding,-
23120,108,0,0,0,0,27,17,0,42,5,1,1,"ATP10B;ATPase, class V, type 10B",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0030659//cytoplasmic vesicle membrane,GO:0045332//phospholipid translocation;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity;GO:0000287//magnesium ion binding,K01530//Purine metabolism
23122,0,0,1,12,120,9,27,0,45,1,14,313,CLASP2;cytoplasmic linker associated protein 2,GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0005802//trans-Golgi network;GO:0005794//Golgi apparatus;GO:0005828//kinetochore microtubule;GO:0005886//plasma membrane;GO:0005881//cytoplasmic microtubule;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0005874//microtubule;GO:0005815//microtubule organizing center;GO:0032587//ruffle membrane;GO:0005829//cytosol,GO:0032886//regulation of microtubule-based process;GO:0007163//establishment or maintenance of cell polarity;GO:0007411//axon guidance;GO:0000278//mitotic cell cycle;GO:0007026//negative regulation of microtubule depolymerization;GO:0007020//microtubule nucleation;GO:0034453//microtubule anchoring;GO:0036065//fucosylation;GO:0007067//mitotic nuclear division;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0031023//microtubule organizing center organization,GO:0051010//microtubule plus-end binding;GO:0005515//protein binding;GO:0008107//galactoside 2-alpha-L-fucosyltransferase activity,-
23125,211,0,0,6,7,24,20,56,29,136,0,268,CAMTA2;calmodulin binding transcription activator 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0008134//transcription factor binding;GO:0003677//DNA binding,K13505//SNARE interactions in vesicular transport;Phagosome
23126,0,1,1,22,43,0,0,0,46,0,0,0,POGZ;pogo transposable element with ZNF domain,GO:0005730//nucleolus;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051382//kinetochore assembly;GO:0007064//mitotic sister chromatid cohesion,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K10500//Cell cycle;Transcriptional misregulation in cancer
23127,0,0,0,17,0,26,21,0,18,0,7,0,COLGALT2;collagen beta(1-O)galactosyltransferase 2,GO:0005788//endoplasmic reticulum lumen,GO:0030198//extracellular matrix organization;GO:0009103//lipopolysaccharide biosynthetic process,GO:0050211//procollagen galactosyltransferase activity,K11703//Lysine degradation;Other types of O-glycan biosynthesis
23129,0,58,5,0,0,40,30,0,20,76,22,2,PLXND1;plexin D1,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005887//integral component of plasma membrane;GO:0030027//lamellipodium,GO:0007416//synapse assembly;GO:0003151//outflow tract morphogenesis;GO:0045765//regulation of angiogenesis;GO:0043542//endothelial cell migration;GO:0001525//angiogenesis;GO:0001569//patterning of blood vessels;GO:0030334//regulation of cell migration;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0032092//positive regulation of protein binding;GO:0071526//semaphorin-plexin signaling pathway;GO:0007411//axon guidance,GO:0019904//protein domain specific binding;GO:0017154//semaphorin receptor activity;GO:0005515//protein binding,-
2313,96,0,0,0,9,0,19,0,52,0,0,1,"FLI1;Fli-1 proto-oncogene, ETS transcription factor",GO:0005634//nucleus,GO:0035855//megakaryocyte development;GO:0009887//organ morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0008015//blood circulation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007599//hemostasis;GO:0030154//cell differentiation,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,K09436//Transcriptional misregulation in cancer
23130,177,0,0,2,3,0,2,46,87,0,1,0,ATG2A;autophagy related 2A,GO:0019898//extrinsic component of membrane;GO:0034045//pre-autophagosomal structure membrane;GO:0005811//lipid particle;GO:0000407//pre-autophagosomal structure,GO:0000045//autophagic vacuole assembly;GO:0006995//cellular response to nitrogen starvation;GO:0000422//mitochondrion degradation,GO:0005515//protein binding,-
23131,0,0,0,8,36,22,30,46,84,0,0,0,GPATCH8;G patch domain containing 8,-,-,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
23132,100,0,1,1,12,2,18,98,50,0,7,0,RAD54L2;RAD54-like 2 (S. cerevisiae),GO:0005634//nucleus,GO:2001141//regulation of RNA biosynthetic process;GO:0008152//metabolic process,GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0003712//transcription cofactor activity;GO:0005524//ATP binding,-
23133,75,1,2,14,32,14,27,64,69,0,0,0,PHF8;PHD finger protein 8,GO:0015630//microtubule cytoskeleton;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0055114//oxidation-reduction process;GO:0006351//transcription, DNA-templated;GO:0007420//brain development;GO:0000278//mitotic cell cycle;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0070544//histone H3-K36 demethylation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0061188//negative regulation of chromatin silencing at rDNA;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035574//histone H4-K20 demethylation;GO:0071557//histone H3-K27 demethylation;GO:0033169//histone H3-K9 demethylation","GO:0035064//methylated histone binding;GO:0032452//histone demethylase activity;GO:0005506//iron ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0003682//chromatin binding;GO:0035575//histone demethylase activity (H4-K20 specific);GO:0008270//zinc ion binding;GO:0032454//histone demethylase activity (H3-K9 specific);GO:0051864//histone demethylase activity (H3-K36 specific);GO:0071558//histone demethylase activity (H3-K27 specific);GO:0005515//protein binding",-
23135,15,0,0,2,0,62,56,0,2,0,0,318,KDM6B;lysine (K)-specific demethylase 6B,GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0045446//endothelial cell differentiation;GO:0048333//mesodermal cell differentiation;GO:0071557//histone H3-K27 demethylation;GO:0055114//oxidation-reduction process;GO:0070301//cellular response to hydrogen peroxide;GO:0055007//cardiac muscle cell differentiation,GO:0008013//beta-catenin binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0071558//histone demethylase activity (H3-K27 specific);GO:0051213//dioxygenase activity,-
23136,0,1,0,7,0,0,46,0,28,0,0,0,EPB41L3;erythrocyte membrane protein band 4.1-like 3,GO:0030673//axolemma;GO:0005886//plasma membrane;GO:0044224//juxtaparanode region of axon;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0033270//paranode region of axon;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton,GO:0002175//protein localization to paranode region of axon;GO:0008360//regulation of cell shape;GO:0030866//cortical actin cytoskeleton organization;GO:0043217//myelin maintenance;GO:0006915//apoptotic process;GO:0072659//protein localization to plasma membrane;GO:0071205//protein localization to juxtaparanode region of axon;GO:0048812//neuron projection morphogenesis;GO:0030913//paranodal junction assembly;GO:0007016//cytoskeletal anchoring at plasma membrane,GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,K06107//Tight junction
23137,16,24,0,37,56,20,0,14,79,0,5,0,SMC5;structural maintenance of chromosomes 5,"GO:0030915//Smc5-Smc6 complex;GO:0016605//PML body;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus",GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0007067//mitotic nuclear division;GO:0090398//cellular senescence;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion,GO:0005524//ATP binding;GO:0005515//protein binding,K06674//Cell cycle - yeast;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K06669//Oocyte meiosis;Meiosis - yeast;Cell cycle - yeast;Cell cycle
23138,65,0,0,0,0,0,0,0,20,0,4,0,N4BP3;NEDD4 binding protein 3,GO:0030659//cytoplasmic vesicle membrane,-,-,-
23139,14,1,1,0,9,7,2,0,31,0,10,0,MAST2;microtubule associated serine/threonine kinase 2,GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation;GO:0045075//regulation of interleukin-12 biosynthetic process;GO:0048515//spermatid differentiation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0019902//phosphatase binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
2314,0,0,0,9,12,0,0,0,48,0,0,0,FLII;flightless I homolog (Drosophila),GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005925//focal adhesion,"GO:0007275//multicellular organismal development;GO:0006936//muscle contraction;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003779//actin binding,K05768//Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis
23140,62,28,1,32,44,28,170,0,174,178,8,6,"ZZEF1;zinc finger, ZZ-type with EF-hand domain 1",-,-,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding,K10595//Ubiquitin mediated proteolysis
23141,120,0,0,4,0,0,0,102,30,1,0,0,ANKLE2;ankyrin repeat and LEM domain containing 2,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016020//membrane,GO:0050790//regulation of catalytic activity;GO:0007084//mitotic nuclear envelope reassembly;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0035307//positive regulation of protein dephosphorylation;GO:0042326//negative regulation of phosphorylation,GO:0051721//protein phosphatase 2A binding;GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,-
23142,0,0,0,2,36,0,0,0,1,0,0,0,"DCUN1D4;DCN1, defective in cullin neddylation 1, domain containing 4",GO:0005634//nucleus,-,GO:0005515//protein binding,-
23143,0,0,1,1,11,33,27,0,55,0,3,0,LRCH1;leucine-rich repeats and calponin homology (CH) domain containing 1,-,-,-,K10130//p53 signaling pathway;NF-kappa B signaling pathway
23144,115,12,0,0,3,6,0,1,49,0,20,0,ZC3H3;zinc finger CCCH-type containing 3,GO:0005634//nucleus,GO:0006378//mRNA polyadenylation;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0010793//regulation of mRNA export from nucleus,GO:0046872//metal ion binding,K06093//Tight junction;Endocytosis;K14404//Influenza A;mRNA surveillance pathway
23145,0,1,0,1,10,20,33,67,255,84,54,0,SSPO;SCO-spondin,GO:0005615//extracellular space,GO:0010466//negative regulation of peptidase activity;GO:0007155//cell adhesion,GO:0030414//peptidase inhibitor activity,K03900//ECM-receptor interaction;Focal adhesion;Complement and coagulation cascades
23148,31,0,0,0,0,15,23,0,69,0,0,0,NACAD;NAC alpha domain containing,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0015031//protein transport,-,-
23149,88,0,0,0,0,8,53,0,33,0,11,0,FCHO1;FCH domain only 1,GO:0005905//coated pit;GO:0005886//plasma membrane;GO:0030136//clathrin-coated vesicle,GO:0072583//clathrin-mediated endocytosis;GO:0048268//clathrin coat assembly,GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding,K12804//NOD-like receptor signaling pathway
2315,0,0,0,2,30,0,0,44,43,0,0,0,MLANA;melan-A,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0042470//melanosome;GO:0005794//Golgi apparatus,-,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
23150,98,0,0,7,76,44,13,0,17,0,0,1,FRMD4B;FERM domain containing 4B,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005615//extracellular space,GO:0090162//establishment of epithelial cell polarity,-,K05762//Regulation of actin cytoskeleton;K12817//Spliceosome;K08007//Gastric acid secretion;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Regulation of actin cytoskeleton
23151,0,0,0,0,0,0,19,20,29,66,23,0,GRAMD4;GRAM domain containing 4,GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane,GO:0006915//apoptotic process,-,-
23152,0,0,0,0,2,0,8,1,34,0,7,0,CIC;capicua transcriptional repressor,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding,K04491//Acute myeloid leukemia;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Prostate cancer;Basal cell carcinoma;Wnt signaling pathway;Endometrial cancer;Melanogenesis;Colorectal cancer;Thyroid cancer;Adherens junction
23154,145,0,0,0,0,4,0,0,7,1,9,0,NCDN;neurochondrin,GO:0043025//neuronal cell body;GO:0005634//nucleus;GO:0030425//dendrite;GO:0030424//axon;GO:0016020//membrane;GO:0005829//cytosol,GO:0045453//bone resorption;GO:0031175//neuron projection development;GO:0048168//regulation of neuronal synaptic plasticity,-,-
23155,101,0,0,0,1,0,0,63,81,0,3,0,CLCC1;chloride channel CLIC-like 1,GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum,GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity,-
23157,0,29,0,6,8,17,0,0,26,0,17,0,SEPT6;septin 6,GO:0043679//axon terminus;GO:0005819//spindle;GO:0030496//midbody;GO:0031105//septin complex;GO:0000777//condensed chromosome kinetochore;GO:0032154//cleavage furrow;GO:0008021//synaptic vesicle,GO:0016032//viral process;GO:0000910//cytokinesis,GO:0005525//GTP binding;GO:0005515//protein binding,K04557//Parkinson's disease
23158,0,83,1,56,169,0,0,0,42,0,17,0,"TBC1D9;TBC1 domain family, member 9 (with GRAM domain)",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005509//calcium ion binding;GO:0005097//Rab GTPase activator activity,-
2316,0,0,1,1,2,41,23,46,53,98,3,0,"FLNA;filamin A, alpha",GO:0005634//nucleus;GO:0005884//actin filament;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030863//cortical cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0005802//trans-Golgi network;GO:0031523//Myb complex;GO:0043198//dendritic shaft;GO:0097440//apical dendrite;GO:0005886//plasma membrane,GO:0090307//spindle assembly involved in mitosis;GO:0002576//platelet degranulation;GO:0042177//negative regulation of protein catabolic process;GO:0042384//cilium assembly;GO:0051764//actin crosslink formation;GO:0007596//blood coagulation;GO:0045184//establishment of protein localization;GO:0045022//early endosome to late endosome transport;GO:0030168//platelet activation;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0070527//platelet aggregation;GO:0034329//cell junction assembly;GO:0050821//protein stabilization;GO:0031532//actin cytoskeleton reorganization;GO:0034394//protein localization to cell surface;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051220//cytoplasmic sequestering of protein;GO:0007195//adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:0001837//epithelial to mesenchymal transition;GO:0043113//receptor clustering;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity,GO:0048365//Rac GTPase binding;GO:0046332//SMAD binding;GO:0001948//glycoprotein binding;GO:0005080//protein kinase C binding;GO:0004871//signal transducer activity;GO:0051015//actin filament binding;GO:0017048//Rho GTPase binding;GO:0017160//Ral GTPase binding;GO:0031852//mu-type opioid receptor binding;GO:0008134//transcription factor binding;GO:0031267//small GTPase binding;GO:0042803//protein homodimerization activity;GO:0034988//Fc-gamma receptor I complex binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K04437//Focal adhesion;MAPK signaling pathway;Salmonella infection
23160,0,0,0,6,59,4,0,0,125,0,16,0,WDR43;WD repeat domain 43,GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,K14546//Ribosome biogenesis in eukaryotes
23161,113,0,0,14,19,8,0,0,37,0,8,0,SNX13;sorting nexin 13,GO:0005769//early endosome;GO:0031901//early endosome membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0006886//intracellular protein transport;GO:0043547//positive regulation of GTPase activity,GO:0035091//phosphatidylinositol binding,-
23162,0,0,0,0,0,73,0,107,24,9,2,203,MAPK8IP3;mitogen-activated protein kinase 8 interacting protein 3,GO:0005790//smooth endoplasmic reticulum;GO:0030673//axolemma;GO:0030425//dendrite;GO:0000139//Golgi membrane,GO:0009791//post-embryonic development;GO:0045666//positive regulation of neuron differentiation;GO:0060425//lung morphogenesis;GO:0048286//lung alveolus development;GO:0001701//in utero embryonic development;GO:0007585//respiratory gaseous exchange;GO:0016192//vesicle-mediated transport;GO:0030900//forebrain development;GO:0046328//regulation of JNK cascade;GO:0008104//protein localization;GO:0007411//axon guidance;GO:0007257//activation of JUN kinase activity;GO:0010468//regulation of gene expression,GO:0005078//MAP-kinase scaffold activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0008432//JUN kinase binding;GO:0019894//kinesin binding;GO:0031434//mitogen-activated protein kinase kinase binding,K04436//MAPK signaling pathway
23163,95,61,8,48,25,20,122,25,60,1,16,0,"GGA3;golgi-associated, gamma adaptin ear containing, ARF binding protein 3",GO:0030131//clathrin adaptor complex;GO:0005802//trans-Golgi network;GO:0010008//endosome membrane,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,GO:0030306//ADP-ribosylation factor binding;GO:0005515//protein binding,K12404//Lysosome
23164,0,0,0,0,12,26,24,0,15,12,23,0,MPRIP;myosin phosphatase Rho interacting protein,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion,-,GO:0003779//actin binding;GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
23165,0,0,20,5,34,12,92,0,41,0,18,0,NUP205;nucleoporin 205kDa,GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0034399//nuclear periphery;GO:0005643//nuclear pore;GO:0016020//membrane,"GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0051292//nuclear pore complex assembly;GO:0005975//carbohydrate metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0000059//protein import into nucleus, docking;GO:0051028//mRNA transport;GO:0006913//nucleocytoplasmic transport;GO:0010827//regulation of glucose transport",GO:0017056//structural constituent of nuclear pore;GO:0005515//protein binding,K14310//RNA transport
23166,187,0,0,0,25,17,119,0,95,171,36,0,STAB1;stabilin 1,GO:0005887//integral component of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane,GO:0007267//cell-cell signaling;GO:0016525//negative regulation of angiogenesis;GO:0006954//inflammatory response;GO:0055114//oxidation-reduction process;GO:0006898//receptor-mediated endocytosis;GO:0042742//defense response to bacterium;GO:0007155//cell adhesion,GO:0005044//scavenger receptor activity;GO:0005041//low-density lipoprotein receptor activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0005540//hyaluronic acid binding,K14616//Vitamin digestion and absorption
23167,0,0,0,85,203,7,23,0,92,0,0,217,EFR3A;EFR3 homolog A (S. cerevisiae),GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,-,-
23168,65,1,55,19,146,0,0,0,40,0,7,0,"RTF1;Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)",GO:0016593//Cdc73/Paf1 complex;GO:0005730//nucleolus,"GO:0016055//Wnt signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001711//endodermal cell fate commitment;GO:0019827//stem cell maintenance;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0080182//histone H3-K4 trimethylation;GO:0051571//positive regulation of histone H3-K4 methylation",GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
23169,0,0,0,9,39,0,9,188,76,0,5,470,"SLC35D1;solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0052695//cellular glucuronidation;GO:0015787//UDP-glucuronic acid transport;GO:0006065//UDP-glucuronate biosynthetic process;GO:0048706//embryonic skeletal system development;GO:0030206//chondroitin sulfate biosynthetic process;GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport;GO:0090481//pyrimidine nucleotide-sugar transmembrane transport,GO:0005461//UDP-glucuronic acid transmembrane transporter activity,-
2317,117,20,45,50,272,59,127,15,68,240,32,15,"FLNB;filamin B, beta",GO:0001725//stress fiber;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0019221//cytokine-mediated signaling pathway;GO:0007165//signal transduction;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0030154//cell differentiation;GO:0007519//skeletal muscle tissue development;GO:0030036//actin cytoskeleton organization,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003779//actin binding,K04437//Salmonella infection;MAPK signaling pathway;Focal adhesion
23170,85,36,0,0,9,0,0,0,45,0,0,0,"TTLL12;tubulin tyrosine ligase-like family, member 12",-,GO:0006464//cellular protein modification process,-,-
23171,0,133,4,154,755,43,0,58,23,0,0,0,GPD1L;glycerol-3-phosphate dehydrogenase 1-like,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0005829//cytosol,GO:0086005//ventricular cardiac muscle cell action potential;GO:0090038//negative regulation of protein kinase C signaling;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0044255//cellular lipid metabolic process;GO:0010765//positive regulation of sodium ion transport;GO:0046168//glycerol-3-phosphate catabolic process;GO:2000010//positive regulation of protein localization to cell surface;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0019674//NAD metabolic process;GO:0006734//NADH metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0002027//regulation of heart rate;GO:0055114//oxidation-reduction process,GO:0042803//protein homodimerization activity;GO:0044325//ion channel binding;GO:0017080//sodium channel regulator activity;GO:0051287//NAD binding;GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity,K00006//Glycerophospholipid metabolism
23172,0,0,0,0,0,0,0,0,17,9,0,0,"FAM175B;family with sequence similarity 175, member B",GO:0005737//cytoplasm;GO:0070552//BRISC complex,-,GO:0031593//polyubiquitin binding,-
23173,0,0,0,29,108,39,15,0,17,0,0,0,METAP1;methionyl aminopeptidase 1,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0022626//cytosolic ribosome,"GO:0018206//peptidyl-methionine modification;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light;GO:0006508//proteolysis;GO:0070527//platelet aggregation;GO:0006417//regulation of translation;GO:0070084//protein initiator methionine removal;GO:0031365//N-terminal protein amino acid modification",GO:0004177//aminopeptidase activity;GO:0046872//metal ion binding;GO:0070006//metalloaminopeptidase activity;GO:0008235//metalloexopeptidase activity,-
23174,0,31,0,6,95,30,61,0,18,212,2,3,"ZCCHC14;zinc finger, CCHC domain containing 14",-,-,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding,-
23175,0,13,1,0,15,0,0,59,38,210,0,0,LPIN1;lipin 1,GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0016311//dephosphorylation;GO:0006642//triglyceride mobilization;GO:0006351//transcription, DNA-templated;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0009062//fatty acid catabolic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process",GO:0008195//phosphatidate phosphatase activity,K15728//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism
23176,0,0,0,38,15,0,4,9,0,0,12,0,SEPT8;septin 8,GO:0031105//septin complex,GO:0007049//cell cycle,GO:0005515//protein binding;GO:0005525//GTP binding,K04557//Parkinson's disease
23177,0,1,34,60,109,30,0,46,58,173,51,1,CEP68;centrosomal protein 68kDa,GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0051297//centrosome organization;GO:0033365//protein localization to organelle;GO:0010457//centriole-centriole cohesion,GO:0019904//protein domain specific binding;GO:0019901//protein kinase binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
23178,200,67,38,103,99,38,42,46,31,1,138,1,PASK;PAS domain containing serine/threonine kinase,GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043576//regulation of respiratory gaseous exchange;GO:0006468//protein phosphorylation;GO:0045727//positive regulation of translation;GO:2000505//regulation of energy homeostasis;GO:0007165//signal transduction;GO:0070092//regulation of glucagon secretion;GO:0046777//protein autophosphorylation;GO:0045719//negative regulation of glycogen biosynthetic process,GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0004674//protein serine/threonine kinase activity;GO:0035091//phosphatidylinositol binding;GO:0005524//ATP binding,-
2318,72,0,0,0,5,52,67,54,34,246,0,0,"FLNC;filamin C, gamma",GO:0043034//costamere;GO:0005886//plasma membrane;GO:0030018//Z disc;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0042383//sarcolemma,GO:0034329//cell junction assembly,GO:0008092//cytoskeletal protein binding;GO:0005515//protein binding;GO:0030506//ankyrin binding;GO:0051015//actin filament binding,K04437//Salmonella infection;MAPK signaling pathway;Focal adhesion
23180,0,0,0,0,0,0,8,65,0,0,16,0,"RFTN1;raftlin, lipid raft linker 1",GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0034138//toll-like receptor 3 signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0001765//membrane raft assembly;GO:0033227//dsRNA transport;GO:1903044//protein localization to membrane raft;GO:0032596//protein transport into membrane raft;GO:0032620//interleukin-17 production;GO:0002457//T cell antigen processing and presentation;GO:0050852//T cell receptor signaling pathway;GO:0040007//growth;GO:0043330//response to exogenous dsRNA,GO:0003725//double-stranded RNA binding,-
23181,0,10,1,11,82,27,72,0,117,90,2,0,DIP2A;DIP2 disco-interacting protein 2 homolog A (Drosophila),GO:0009986//cell surface;GO:0005634//nucleus,GO:0008152//metabolic process;GO:0007275//multicellular organismal development;GO:0042981//regulation of apoptotic process;GO:0010629//negative regulation of gene expression,GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003824//catalytic activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
23184,60,0,0,0,0,2,28,0,0,0,0,0,MESDC2;mesoderm development candidate 2,GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum,GO:0034394//protein localization to cell surface;GO:0006457//protein folding;GO:0007498//mesoderm development;GO:0016055//Wnt signaling pathway,GO:0050750//low-density lipoprotein particle receptor binding,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
23185,0,101,23,80,116,27,11,0,66,0,0,0,"LARP4B;La ribonucleoprotein domain family, member 4B",GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0042788//polysomal ribosome;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule,GO:0045727//positive regulation of translation,GO:0044822//poly(A) RNA binding,-
23186,0,22,0,14,47,0,19,0,46,312,14,0,RCOR1;REST corepressor 1,GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0007596//blood coagulation;GO:0016032//viral process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070933//histone H4 deacetylation;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding,K11829//Huntington's disease
23187,0,0,53,0,0,6,9,49,88,221,6,0,"PHLDB1;pleckstrin homology-like domain, family B, member 1",-,-,-,-
23189,0,7,0,21,85,0,43,74,71,2,59,0,KANK1;KN motif and ankyrin repeat domains 1,GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0030177//positive regulation of Wnt signaling pathway;GO:1900028//negative regulation of ruffle assembly;GO:0030336//negative regulation of cell migration;GO:0090303//positive regulation of wound healing;GO:2000114//regulation of establishment of cell polarity;GO:2000393//negative regulation of lamellipodium morphogenesis;GO:0035413//positive regulation of catenin import into nucleus;GO:0006351//transcription, DNA-templated;GO:0035024//negative regulation of Rho protein signal transduction;GO:0010977//negative regulation of neuron projection development;GO:0006355//regulation of transcription, DNA-templated;GO:0030837//negative regulation of actin filament polymerization;GO:0046627//negative regulation of insulin receptor signaling pathway",GO:0008013//beta-catenin binding;GO:0005515//protein binding,-
2319,49,11,0,0,9,0,11,1,0,0,0,0,FLOT2;flotillin 2,GO:0031982//vesicle;GO:0002080//acrosomal membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0016600//flotillin complex;GO:0005925//focal adhesion;GO:0030139//endocytic vesicle,GO:0007155//cell adhesion;GO:0090002//establishment of protein localization to plasma membrane;GO:0050821//protein stabilization;GO:0008544//epidermis development;GO:0010629//negative regulation of gene expression,GO:0005515//protein binding;GO:0035255//ionotropic glutamate receptor binding,K07192//Insulin signaling pathway
23190,0,24,0,49,83,0,0,23,1,68,2,0,UBXN4;UBX domain protein 4,GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0006986//response to unfolded protein,GO:0005515//protein binding,-
23191,0,119,1,19,107,0,0,0,16,0,16,0,CYFIP1;cytoplasmic FMR1 interacting protein 1,GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005845//mRNA cap binding complex;GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0005925//focal adhesion;GO:0048471//perinuclear region of cytoplasm,GO:0048675//axon extension;GO:0050890//cognition;GO:0031529//ruffle organization;GO:0016601//Rac protein signal transduction;GO:0008360//regulation of cell shape;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0030032//lamellipodium assembly,GO:0005515//protein binding;GO:0051015//actin filament binding;GO:0048365//Rac GTPase binding;GO:0032403//protein complex binding,K05749//RNA transport;Regulation of actin cytoskeleton
23192,41,0,0,0,29,17,0,0,13,109,0,0,"ATG4B;autophagy related 4B, cysteine peptidase",GO:0005737//cytoplasm,GO:0006914//autophagy;GO:0000045//autophagic vacuole assembly;GO:0015031//protein transport;GO:0006508//proteolysis;GO:0045732//positive regulation of protein catabolic process;GO:0010508//positive regulation of autophagy,GO:0004175//endopeptidase activity;GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity,K08342//Regulation of autophagy
23193,0,0,0,0,40,3,11,0,30,0,0,0,"GANAB;glucosidase, alpha; neutral AB",GO:0005788//endoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0016020//membrane;GO:0017177//glucosidase II complex,GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006457//protein folding,"GO:0030246//carbohydrate binding;GO:0033919//glucan 1,3-alpha-glucosidase activity;GO:0044822//poly(A) RNA binding",K05546//N-Glycan biosynthesis;Protein processing in endoplasmic reticulum;Metabolic pathways
23194,0,0,0,4,0,0,47,0,28,0,6,0,FBXL7;F-box and leucine-rich repeat protein 7,GO:0000151//ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0008283//cell proliferation;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity,-
23195,0,21,0,11,182,108,50,72,205,0,57,0,"MDN1;MDN1, midasin homolog (yeast)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0016020//membrane,GO:0006461//protein complex assembly;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0016887//ATPase activity;GO:0005515//protein binding,K14572//Ribosome biogenesis in eukaryotes
23196,0,187,37,45,204,27,48,135,45,1,11,194,FAM120A;family with sequence similarity 120A,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016020//membrane,-,GO:0044822//poly(A) RNA binding,-
23197,0,0,0,0,7,28,22,0,17,54,0,0,FAF2;Fas associated factor family member 2,GO:0043231//intracellular membrane-bounded organelle;GO:0034098//Cdc48p-Npl4p-Ufd1p AAA ATPase complex;GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum,GO:0043086//negative regulation of catalytic activity;GO:0006986//response to unfolded protein;GO:0034389//lipid particle organization,GO:0043130//ubiquitin binding;GO:0035473//lipase binding;GO:0055102//lipase inhibitor activity;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,-
23198,0,0,1,53,112,10,19,0,78,0,0,0,"PSME4;proteasome (prosome, macropain) activator subunit 4",GO:0016607//nuclear speck;GO:0005829//cytosol;GO:1990111//spermatoproteasome complex;GO:0005634//nucleus,"GO:0000209//protein polyubiquitination;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:0006915//apoptotic process;GO:0010952//positive regulation of peptidase activity;GO:0007275//multicellular organismal development;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006974//cellular response to DNA damage stimulus;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0006281//DNA repair;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0016504//peptidase activator activity;GO:0070577//lysine-acetylated histone binding,K06699//Proteasome
23199,0,135,0,34,57,0,22,22,33,0,28,0,GSE1;Gse1 coiled-coil protein,-,-,GO:0005515//protein binding,-
23200,0,3,0,1,107,12,0,0,76,0,6,2,"ATP11B;ATPase, class VI, type 11B",GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0005637//nuclear inner membrane,GO:0055085//transmembrane transport;GO:0015917//aminophospholipid transport;GO:0008152//metabolic process;GO:0006811//ion transport;GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport,GO:0000287//magnesium ion binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity;GO:0015075//ion transmembrane transporter activity;GO:0005524//ATP binding;GO:0005515//protein binding,K01530//Purine metabolism
23201,0,52,39,24,155,10,0,0,36,0,11,0,"FAM168A;family with sequence similarity 168, member A",-,-,-,-
23203,0,0,0,0,5,14,0,122,12,0,0,0,PMPCA;peptidase (mitochondrial processing) alpha,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane,GO:0006626//protein targeting to mitochondrion;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
23204,0,45,0,2,79,0,1,0,38,0,0,0,ARL6IP1;ADP-ribosylation factor-like 6 interacting protein 1,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005784//Sec61 translocon complex,GO:0006613//cotranslational protein targeting to membrane,GO:0005515//protein binding,-
23205,0,38,0,0,33,31,0,41,0,0,0,1,ACSBG1;acyl-CoA synthetase bubblegum family member 1,GO:0005783//endoplasmic reticulum;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005737//cytoplasm,GO:0051384//response to glucocorticoid;GO:0001676//long-chain fatty acid metabolic process;GO:0001552//ovarian follicle atresia;GO:0000038//very long-chain fatty acid metabolic process;GO:0042552//myelination,GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0031957//very long-chain fatty acid-CoA ligase activity,K15013//Fatty acid metabolism;Metabolic pathways;PPAR signaling pathway;Adipocytokine signaling pathway
23207,0,1,0,1,2,60,83,46,52,161,1,0,"PLEKHM2;pleckstrin homology domain containing, family M (with RUN domain) member 2",GO:0005737//cytoplasm,GO:0007030//Golgi organization,GO:0019894//kinesin binding;GO:0005515//protein binding,K15348//Salmonella infection
23208,0,0,0,0,0,23,0,0,2,0,11,143,SYT11;synaptotagmin XI,GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle,GO:0006810//transport;GO:0046929//negative regulation of neurotransmitter secretion,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
23209,0,0,0,0,0,0,39,51,46,0,21,0,MLC1;megalencephalic leukoencephalopathy with subcortical cysts 1,GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016323//basolateral plasma membrane;GO:0005901//caveola;GO:0005764//lysosome;GO:0005768//endosome;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0072584//caveolin-mediated endocytosis;GO:0015031//protein transport;GO:0006810//transport;GO:0071397//cellular response to cholesterol;GO:0006811//ion transport;GO:0032388//positive regulation of intracellular transport;GO:0051259//protein oligomerization;GO:0016192//vesicle-mediated transport;GO:0047484//regulation of response to osmotic stress,GO:0005215//transporter activity;GO:0032403//protein complex binding;GO:0008565//protein transporter activity;GO:0005515//protein binding,-
2321,223,0,51,0,0,10,14,23,78,0,0,0,FLT1;fms-related tyrosine kinase 1,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005768//endosome;GO:0005615//extracellular space,GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0036323//vascular endothelial growth factor receptor-1 signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043410//positive regulation of MAPK cascade;GO:0045766//positive regulation of angiogenesis;GO:0002040//sprouting angiogenesis;GO:0008284//positive regulation of cell proliferation;GO:0043406//positive regulation of MAP kinase activity;GO:0002548//monocyte chemotaxis;GO:0048598//embryonic morphogenesis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048514//blood vessel morphogenesis;GO:0016477//cell migration;GO:0030154//cell differentiation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0046777//protein autophosphorylation;GO:0001569//patterning of blood vessels,GO:0036332//placental growth factor-activated receptor activity;GO:0042802//identical protein binding;GO:0036327//VEGF-B-activated receptor activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0036326//VEGF-A-activated receptor activity;GO:0019838//growth factor binding;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity,K05096//Rheumatoid arthritis;Endocytosis;Cytokine-cytokine receptor interaction;Transcriptional misregulation in cancer;Focal adhesion
23210,18,0,46,0,12,42,5,49,38,0,0,0,JMJD6;jumonji domain containing 6,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0033077//T cell differentiation in thymus;GO:0007166//cell surface receptor signaling pathway;GO:0030324//lung development;GO:0018395//peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine;GO:0070079//histone H4-R3 demethylation;GO:0055114//oxidation-reduction process;GO:0060041//retina development in camera-type eye;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043654//recognition of apoptotic cell;GO:0006351//transcription, DNA-templated;GO:0070078//histone H3-R2 demethylation;GO:0042116//macrophage activation;GO:0048821//erythrocyte development;GO:0007507//heart development;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0001822//kidney development;GO:0002040//sprouting angiogenesis",GO:0033749//histone demethylase activity (H4-R3 specific);GO:0003727//single-stranded RNA binding;GO:0070815//peptidyl-lysine 5-dioxygenase activity;GO:0005506//iron ion binding;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0004872//receptor activity;GO:0005515//protein binding;GO:0033746//histone demethylase activity (H3-R2 specific),-
23211,0,0,1,22,23,11,28,8,40,0,10,0,ZC3H4;zinc finger CCCH-type containing 4,-,-,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,K14404//Influenza A;mRNA surveillance pathway
23212,0,0,0,9,7,0,19,0,0,0,0,0,RRS1;RRS1 ribosome biogenesis regulator homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome;GO:0005783//endoplasmic reticulum,GO:0007080//mitotic metaphase plate congression;GO:0042254//ribosome biogenesis;GO:0002244//hematopoietic progenitor cell differentiation,GO:0044822//poly(A) RNA binding,-
23213,22,0,0,0,0,4,0,64,20,0,2,0,SULF1;sulfatase 1,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005795//Golgi stack;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0005615//extracellular space,GO:0002063//chondrocyte development;GO:0060348//bone development;GO:0030177//positive regulation of Wnt signaling pathway;GO:0006915//apoptotic process;GO:0060384//innervation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0060686//negative regulation of prostatic bud formation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0048706//embryonic skeletal system development;GO:0016525//negative regulation of angiogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0032836//glomerular basement membrane development;GO:0003094//glomerular filtration;GO:0030336//negative regulation of cell migration;GO:0030201//heparan sulfate proteoglycan metabolic process;GO:0014846//esophagus smooth muscle contraction;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0051216//cartilage development;GO:0001822//kidney development;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway,GO:0004065//arylsulfatase activity;GO:0005509//calcium ion binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity,-
23214,0,0,0,21,35,30,39,0,66,0,20,0,XPO6;exportin 6,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006611//protein export from nucleus,GO:0008536//Ran GTPase binding;GO:0008565//protein transporter activity;GO:0005515//protein binding,-
23215,61,18,0,4,104,4,109,0,74,140,0,0,PRRC2C;proline-rich coiled-coil 2C,GO:0016020//membrane,GO:0002244//hematopoietic progenitor cell differentiation,GO:0044822//poly(A) RNA binding;GO:0008022//protein C-terminus binding,-
23216,81,0,0,0,55,63,2,59,42,40,16,0,"TBC1D1;TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1",GO:0005634//nucleus;GO:0005829//cytosol,GO:1902017//regulation of cilium assembly;GO:0061024//membrane organization;GO:0032851//positive regulation of Rab GTPase activity;GO:0032880//regulation of protein localization,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
23217,4,0,0,0,11,11,28,0,82,0,11,0,ZFR2;zinc finger RNA binding protein 2,-,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K12968//Cytosolic DNA-sensing pathway;Influenza A;Measles
23218,0,25,0,0,0,18,5,143,98,19,0,0,NBEAL2;neurobeachin-like 2,GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0035855//megakaryocyte development;GO:0070889//platelet alpha granule organization;GO:0030220//platelet formation;GO:0007596//blood coagulation,-,-
23219,1,0,1,2,100,56,0,0,60,0,1,0,FBXO28;F-box protein 28,-,-,-,-
2322,0,0,0,0,0,16,34,0,41,3,0,0,FLT3;fms-related tyrosine kinase 3,GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005788//endoplasmic reticulum lumen,GO:0042981//regulation of apoptotic process;GO:0002318//myeloid progenitor cell differentiation;GO:0030183//B cell differentiation;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071345//cellular response to cytokine stimulus;GO:0046651//lymphocyte proliferation;GO:0046777//protein autophosphorylation;GO:0045578//negative regulation of B cell differentiation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0001776//leukocyte homeostasis;GO:0035726//common myeloid progenitor cell proliferation;GO:0002328//pro-B cell differentiation;GO:0030097//hemopoiesis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0002572//pro-T cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0097028//dendritic cell differentiation;GO:0043406//positive regulation of MAP kinase activity;GO:0008285//negative regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004896//cytokine receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005524//ATP binding,K05092//Transcriptional misregulation in cancer;Pathways in cancer;Acute myeloid leukemia;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction
23220,0,0,0,0,0,0,0,0,3,0,0,0,"DTX4;deltex 4, E3 ubiquitin ligase",GO:0005829//cytosol,GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway,GO:0016874//ligase activity;GO:0008270//zinc ion binding,K06058//Notch signaling pathway
23221,85,0,0,32,26,38,98,0,8,36,36,156,RHOBTB2;Rho-related BTB domain containing 2,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005525//GTP binding,K07868//Ubiquitin mediated proteolysis
23223,0,41,0,0,4,17,35,51,23,0,11,0,RRP12;ribosomal RNA processing 12 homolog (S. cerevisiae),GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
23224,52,74,1,45,106,23,88,21,329,206,14,0,"SYNE2;spectrin repeat containing, nuclear envelope 2",GO:0005739//mitochondrion;GO:0045111//intermediate filament cytoskeleton;GO:0031258//lamellipodium membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005640//nuclear outer membrane;GO:0005635//nuclear envelope;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane;GO:0016235//aggresome;GO:0034993//SUN-KASH complex;GO:0031981//nuclear lumen;GO:0016529//sarcoplasmic reticulum;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0031527//filopodium membrane;GO:0005654//nucleoplasm;GO:0030018//Z disc;GO:0005737//cytoplasm,GO:0034504//protein localization to nucleus;GO:0006998//nuclear envelope organization;GO:0007097//nuclear migration;GO:0007163//establishment or maintenance of cell polarity;GO:0030335//positive regulation of cell migration;GO:0031022//nuclear migration along microfilament;GO:0010761//fibroblast migration;GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0051642//centrosome localization,GO:0003779//actin binding;GO:0005515//protein binding,K06115//Tight junction
23225,357,0,0,9,5,13,92,65,29,114,15,163,NUP210;nucleoporin 210kDa,GO:0016020//membrane;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane,GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport,GO:0046983//protein dimerization activity,K14314//RNA transport
23228,0,0,0,0,0,7,0,0,61,0,0,0,PLCL2;phospholipase C-like 2,GO:0005737//cytoplasm,"GO:0035556//intracellular signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0002322//B cell proliferation involved in immune response;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0006629//lipid metabolic process;GO:1900122//positive regulation of receptor binding;GO:0033135//regulation of peptidyl-serine phosphorylation",GO:0050811//GABA receptor binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity,-
23229,16,31,2,19,94,81,41,59,54,0,0,0,ARHGEF9;Cdc42 guanine nucleotide exchange factor (GEF) 9,GO:0005829//cytosol,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0034220//ion transmembrane transport,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K05769//Regulation of actin cytoskeleton
2323,73,0,0,0,0,0,0,0,0,0,0,0,FLT3LG;fms-related tyrosine kinase 3 ligand,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005615//extracellular space;GO:0031233//intrinsic component of external side of plasma membrane,GO:0030098//lymphocyte differentiation;GO:0035162//embryonic hemopoiesis;GO:0032825//positive regulation of natural killer cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0007165//signal transduction;GO:0001934//positive regulation of protein phosphorylation,GO:0005102//receptor binding;GO:0030971//receptor tyrosine kinase binding;GO:0042803//protein homodimerization activity;GO:0005125//cytokine activity,K05454//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Pathways in cancer
23230,0,0,34,0,24,63,90,203,161,12,20,77,VPS13A;vacuolar protein sorting 13 homolog A (S. cerevisiae),GO:0005622//intracellular;GO:0031045//dense core granule,GO:0006895//Golgi to endosome transport;GO:0015031//protein transport;GO:0007399//nervous system development;GO:0008104//protein localization;GO:0035176//social behavior;GO:0008219//cell death;GO:0007626//locomotory behavior,GO:0005515//protein binding,-
23231,36,0,0,0,0,14,48,0,37,0,9,0,SEL1L3;sel-1 suppressor of lin-12-like 3 (C. elegans),GO:0016021//integral component of membrane,-,-,-
23232,0,1,20,28,86,48,40,80,37,66,10,0,"TBC1D12;TBC1 domain family, member 12",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
23233,8,0,1,0,20,0,0,0,18,0,0,0,EXOC6B;exocyst complex component 6B,GO:0000145//exocyst,GO:0006904//vesicle docking involved in exocytosis;GO:0015031//protein transport,-,-
23234,0,0,3,22,35,0,0,0,18,0,0,0,"DNAJC9;DnaJ (Hsp40) homolog, subfamily C, member 9",GO:0005634//nucleus,GO:0035176//social behavior,-,-
23235,0,15,1,24,155,20,20,114,15,116,40,0,SIK2;salt-inducible kinase 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008286//insulin receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0046626//regulation of insulin receptor signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
23236,0,19,1,21,43,2,0,0,54,87,0,0,"PLCB1;phospholipase C, beta 1 (phosphoinositide-specific)",GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0048639//positive regulation of developmental growth;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0045663//positive regulation of myoblast differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000560//positive regulation of CD24 biosynthetic process;GO:0035723//interleukin-15-mediated signaling pathway;GO:2000344//positive regulation of acrosome reaction;GO:0007165//signal transduction;GO:2000438//negative regulation of monocyte extravasation;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0045444//fat cell differentiation;GO:0070498//interleukin-1-mediated signaling pathway;GO:0007268//synaptic transmission;GO:0000086//G2/M transition of mitotic cell cycle;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043547//positive regulation of GTPase activity;GO:0035722//interleukin-12-mediated signaling pathway;GO:0016042//lipid catabolic process;GO:0046330//positive regulation of JNK cascade;GO:0007215//glutamate receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0080154//regulation of fertilization;GO:0007613//memory;GO:0060466//activation of meiosis involved in egg activation;GO:0043647//inositol phosphate metabolic process;GO:0046488//phosphatidylinositol metabolic process;GO:0021987//cerebral cortex development;GO:0032735//positive regulation of interleukin-12 production;GO:0040019//positive regulation of embryonic development","GO:0005509//calcium ion binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0042803//protein homodimerization activity;GO:0005521//lamin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005096//GTPase activator activity;GO:0004871//signal transducer activity;GO:0005516//calmodulin binding;GO:0019899//enzyme binding",K05858//Cholinergic synapse;Long-term depression;Chagas disease (American trypanosomiasis);Salivary secretion;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Alzheimer's disease;Melanogenesis;Inositol phosphate metabolism;Gastric acid secretion;Huntington's disease;Chemokine signaling pathway;Phosphatidylinositol signaling system;GnRH signaling pathway;Gap junction;Dopaminergic synapse;Long-term potentiation;Carbohydrate digestion and absorption;Serotonergic synapse;African trypanosomiasis;Pancreatic secretion;Wnt signaling pathway;Vascular smooth muscle contraction;Metabolic pathways;Taste transduction;Glutamatergic synapse;Amoebiasis;Phototransduction - fly
23237,0,0,0,0,0,29,3,3,61,0,0,0,ARC;activity-regulated cytoskeleton-associated protein,GO:0030054//cell junction;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0015629//actin cytoskeleton;GO:0001669//acrosomal vesicle,GO:0007010//cytoskeleton organization;GO:0007612//learning;GO:0007492//endoderm development;GO:0006897//endocytosis;GO:0009952//anterior/posterior pattern specification;GO:0048168//regulation of neuronal synaptic plasticity;GO:0022604//regulation of cell morphogenesis;GO:0016477//cell migration,-,K15867//Amphetamine addiction
23239,0,4,1,0,36,23,41,0,11,0,11,0,PHLPP1;PH domain and leucine rich repeat protein phosphatase 1,GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009649//entrainment of circadian clock;GO:0006915//apoptotic process;GO:0016311//dephosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway,GO:0004721//phosphoprotein phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
2324,1,0,0,0,0,2,15,72,39,0,6,0,FLT4;fms-related tyrosine kinase 4,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0008284//positive regulation of cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0002040//sprouting angiogenesis;GO:0060312//regulation of blood vessel remodeling;GO:0001938//positive regulation of endothelial cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0046330//positive regulation of JNK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:0001945//lymph vessel development;GO:0090037//positive regulation of protein kinase C signaling;GO:0046777//protein autophosphorylation;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0001946//lymphangiogenesis;GO:0048514//blood vessel morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001944//vasculature development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0010575//positive regulation vascular endothelial growth factor production,GO:0005515//protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding,K05097//Focal adhesion;Cytokine-cytokine receptor interaction
23240,237,1,0,0,0,32,17,0,40,0,0,0,KIAA0922;KIAA0922,GO:0016021//integral component of membrane,-,-,-
23241,0,0,0,2,1,0,9,1,14,0,0,1,PACS2;phosphofurin acidic cluster sorting protein 2,GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen,GO:0006915//apoptotic process;GO:0072661//protein targeting to plasma membrane;GO:0016032//viral process;GO:0000045//autophagic vacuole assembly;GO:0034497//protein localization to pre-autophagosomal structure,-,K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
23242,61,34,0,19,81,25,28,0,15,0,4,556,COBL;cordon-bleu WH2 repeat protein,GO:0030424//axon;GO:0044294//dendritic growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0005884//actin filament;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0001726//ruffle;GO:0016020//membrane;GO:0005938//cell cortex;GO:0044295//axonal growth cone;GO:0043025//neuronal cell body,GO:0000578//embryonic axis specification;GO:0033504//floor plate development;GO:0030903//notochord development;GO:0001889//liver development;GO:0048565//digestive tract development;GO:0001843//neural tube closure;GO:0001757//somite specification;GO:1900006//positive regulation of dendrite development;GO:0030041//actin filament polymerization;GO:0051639//actin filament network formation;GO:0048669//collateral sprouting in absence of injury,GO:0003785//actin monomer binding,-
23243,0,11,0,20,40,0,0,123,57,0,0,0,ANKRD28;ankyrin repeat domain 28,GO:0005654//nucleoplasm,-,GO:0005515//protein binding,-
23244,0,49,0,97,249,42,20,61,85,0,19,0,"PDS5A;PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)","GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005694//chromosome;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0000785//chromatin;GO:0005730//nucleolus;GO:0005829//cytosol",GO:0000278//mitotic cell cycle;GO:0008156//negative regulation of DNA replication;GO:0007064//mitotic sister chromatid cohesion,GO:0005515//protein binding,-
23245,124,0,0,14,4,28,40,1,49,0,1,0,ASTN2;astrotactin 2,GO:0060187//cell pole;GO:0016021//integral component of membrane;GO:0005768//endosome,GO:2000009//negative regulation of protein localization to cell surface,-,K13755//Purine metabolism;Calcium signaling pathway;Olfactory transduction;Morphine addiction;Taste transduction;K06478//Cell adhesion molecules (CAMs);Primary immunodeficiency;T cell receptor signaling pathway;Fc gamma R-mediated phagocytosis;K04559//Huntington's disease
23246,0,2,0,0,1,0,0,0,1,0,0,0,BOP1;block of proliferation 1,"GO:0030529//ribonucleoprotein complex;GO:0030687//preribosome, large subunit precursor;GO:0005654//nucleoplasm;GO:0070545//PeBoW complex","GO:0008283//cell proliferation;GO:0051726//regulation of cell cycle;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042254//ribosome biogenesis",GO:0043021//ribonucleoprotein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
23247,0,0,0,4,52,12,5,0,96,0,16,268,KIAA0556;KIAA0556,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005615//extracellular space,-,-,K10955//Vibrio cholerae infection;Amoebiasis;K13911//Salivary secretion
23248,0,1,0,0,8,0,0,0,0,0,0,0,RPRD2;regulation of nuclear pre-mRNA domain containing 2,"GO:0016591//DNA-directed RNA polymerase II, holoenzyme",-,-,-
23250,0,0,0,0,6,18,87,67,71,0,20,0,"ATP11A;ATPase, class VI, type 11A",GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005765//lysosomal membrane;GO:0055037//recycling endosome,GO:0045332//phospholipid translocation;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity;GO:0005524//ATP binding,K01530//Purine metabolism
23251,0,0,0,0,34,0,59,0,58,0,25,0,KIAA1024;KIAA1024,GO:0016021//integral component of membrane,-,-,-
23252,0,0,0,3,38,13,13,0,35,0,0,0,OTUD3;OTU deubiquitinase 3,-,GO:0044313//protein K6-linked deubiquitination;GO:0006508//proteolysis;GO:0035871//protein K11-linked deubiquitination,GO:0004843//ubiquitin-specific protease activity,-
23253,0,2,47,93,329,12,0,212,171,2,25,0,ANKRD12;ankyrin repeat domain 12,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
23254,0,0,0,0,32,22,105,0,115,0,0,0,"KAZN;kazrin, periplakin interacting protein",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0001533//cornified envelope;GO:0030057//desmosome,GO:0031424//keratinization,-,K04407//MAPK signaling pathway
23255,0,0,0,0,0,21,70,51,77,0,0,0,MTCL1;microtubule crosslinking factor 1,GO:0016328//lateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0016327//apicolateral plasma membrane;GO:0005856//cytoskeleton;GO:0097427//microtubule bundle;GO:0005615//extracellular space;GO:0030496//midbody;GO:0000922//spindle pole,GO:0001578//microtubule bundle formation;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0090314//positive regulation of protein targeting to membrane;GO:0010506//regulation of autophagy,GO:0044822//poly(A) RNA binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K10375//Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;K10373//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction;K09290//Dilated cardiomyopathy;Cardiac muscle contraction;Thyroid cancer;Pathways in cancer;Hypertrophic cardiomyopathy (HCM)
23256,180,35,0,56,28,0,0,0,71,0,0,0,SCFD1;sec1 family domain containing 1,GO:0005789//endoplasmic reticulum membrane;GO:0005798//Golgi-associated vesicle;GO:0017119//Golgi transport complex;GO:0032580//Golgi cisterna membrane;GO:0005801//cis-Golgi network;GO:0005886//plasma membrane,"GO:0009636//response to toxic substance;GO:0015031//protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006904//vesicle docking involved in exocytosis;GO:0001666//response to hypoxia;GO:0006892//post-Golgi vesicle-mediated transport;GO:0060628//regulation of ER to Golgi vesicle-mediated transport",GO:0047485//protein N-terminus binding;GO:0005515//protein binding;GO:0019905//syntaxin binding,K12479//Endocytosis
23258,0,43,0,1,3,36,37,48,105,221,3,0,DENND5A;DENN/MADD domain containing 5A,GO:0005794//Golgi apparatus;GO:0016020//membrane,GO:0050982//detection of mechanical stimulus;GO:0032851//positive regulation of Rab GTPase activity,GO:0017137//Rab GTPase binding;GO:0005262//calcium channel activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
23259,0,37,0,29,134,17,34,0,23,0,0,0,DDHD2;DDHD domain containing 2,GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005737//cytoplasm,GO:0016042//lipid catabolic process;GO:0008219//cell death,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,-
2326,0,0,0,0,0,0,46,0,24,0,0,0,FMO1;flavin containing monooxygenase 1,GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0070995//NADPH oxidation;GO:0009404//toxin metabolic process;GO:0006082//organic acid metabolic process,"GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004497//monooxygenase activity;GO:0050661//NADP binding",K00485//Methane metabolism;Microbial metabolism in diverse environments;Drug metabolism - cytochrome P450
23261,66,0,0,29,2,45,30,0,8,0,1,3,CAMTA1;calmodulin binding transcription activator 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,K13505//Phagosome;SNARE interactions in vesicular transport
23262,3,0,0,23,68,0,77,57,47,0,13,218,PPIP5K2;diphosphoinositol pentakisphosphate kinase 2,GO:0005829//cytosol,GO:0006020//inositol metabolic process;GO:0016311//dephosphorylation;GO:0016310//phosphorylation;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process,"GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0003993//acid phosphatase activity;GO:0005524//ATP binding;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0033857//diphosphoinositol-pentakisphosphate kinase activity",-
23263,0,31,0,21,82,20,64,74,41,240,53,67,MCF2L;MCF.2 cell line derived transforming sequence-like,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0030027//lamellipodium,GO:0007266//Rho protein signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process,GO:0005545//1-phosphatidylinositol binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
23264,0,0,0,4,120,0,20,2,50,122,7,0,ZC3H7B;zinc finger CCCH-type containing 7B,GO:0005634//nucleus,GO:0016032//viral process,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
23265,0,16,2,11,102,0,0,68,114,0,17,6,EXOC7;exocyst complex component 7,GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0034451//centriolar satellite;GO:0005815//microtubule organizing center;GO:0032584//growth cone membrane;GO:0000145//exocyst,GO:0006887//exocytosis;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding,K07195//Insulin signaling pathway
23268,0,0,0,0,72,39,11,0,44,0,7,0,DNMBP;dynamin binding protein,GO:0005856//cytoskeleton;GO:0005795//Golgi stack;GO:0045202//synapse;GO:0030054//cell junction,GO:0032321//positive regulation of Rho GTPase activity;GO:0035556//intracellular signal transduction,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K12365//Chemokine signaling pathway
23269,187,3,26,72,273,12,57,0,77,93,7,0,"MGA;MGA, MAX dimerization protein",GO:0005667//transcription factor complex;GO:0071339//MLL1 complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
2327,201,0,0,0,0,0,17,0,0,0,0,0,FMO2;flavin containing monooxygenase 2 (non-functional),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006739//NADP metabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0072592//oxygen metabolic process;GO:0009404//toxin metabolic process;GO:0070995//NADPH oxidation;GO:0006082//organic acid metabolic process;GO:0017144//drug metabolic process,"GO:0050661//NADP binding;GO:0004497//monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004499//N,N-dimethylaniline monooxygenase activity",K00485//Drug metabolism - cytochrome P450;Microbial metabolism in diverse environments;Methane metabolism
23270,0,0,0,11,9,21,0,0,20,0,0,0,TSPYL4;TSPY-like 4,GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
23272,0,76,1,40,129,29,35,65,82,0,22,0,"FAM208A;family with sequence similarity 208, member A",-,-,GO:0044822//poly(A) RNA binding,K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
23274,57,2,1,0,5,0,27,63,29,140,24,0,"CLEC16A;C-type lectin domain family 16, member A",-,-,-,-
23275,0,0,0,0,0,22,0,0,19,0,8,0,POFUT2;protein O-fucosyltransferase 2,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0010468//regulation of gene expression;GO:0001707//mesoderm formation;GO:0051046//regulation of secretion;GO:0006004//fucose metabolic process;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0036066//protein O-linked fucosylation,GO:0046922//peptide-O-fucosyltransferase activity,K03691//Other types of O-glycan biosynthesis
23276,0,21,0,8,33,8,41,0,65,1,0,0,KLHL18;kelch-like family member 18,-,-,-,-
23277,3,0,0,0,21,7,46,0,34,4,15,0,CLUH;clustered mitochondria (cluA/CLU1) homolog,GO:0005737//cytoplasm,GO:0048312//intracellular distribution of mitochondria,-,-
23279,0,2,1,11,59,0,0,0,36,0,15,0,NUP160;nucleoporin 160kDa,GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0000776//kinetochore;GO:0005829//cytosol;GO:0031080//nuclear pore outer ring,GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0010827//regulation of glucose transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015758//glucose transport,GO:0005515//protein binding;GO:0005487//nucleocytoplasmic transporter activity,K14303//RNA transport
2328,0,0,0,0,0,7,14,0,0,0,0,0,FMO3;flavin containing monooxygenase 3,GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process,"GO:0034899//trimethylamine monooxygenase activity;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0016597//amino acid binding",K00485//Drug metabolism - cytochrome P450;Microbial metabolism in diverse environments;Methane metabolism
23281,0,0,0,0,0,0,16,0,82,0,15,0,MTUS2;microtubule associated tumor suppressor candidate 2,GO:0005881//cytoplasmic microtubule;GO:0005813//centrosome,-,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity,-
23283,0,0,0,28,59,0,35,0,15,0,0,0,"CSTF2T;cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant",GO:0005634//nucleus;GO:0005622//intracellular,GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K14407//mRNA surveillance pathway
23284,0,0,0,0,0,6,0,4,14,0,7,0,LPHN3;latrophilin 3,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0030246//carbohydrate binding,-
23285,67,0,0,2,6,46,33,0,30,0,0,0,KIAA1107;KIAA1107,-,-,-,-
23286,46,0,1,48,85,14,0,1,51,0,6,0,WWC1;WW and C2 domain containing 1,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0032587//ruffle membrane;GO:0005829//cytosol,"GO:0046621//negative regulation of organ growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035329//hippo signaling;GO:0035330//regulation of hippo signaling;GO:0006351//transcription, DNA-templated;GO:0032386//regulation of intracellular transport;GO:0035331//negative regulation of hippo signaling;GO:0016477//cell migration;GO:0030010//establishment of cell polarity;GO:0043410//positive regulation of MAPK cascade","GO:0030674//protein binding, bridging;GO:0005515//protein binding;GO:0019900//kinase binding;GO:0003713//transcription coactivator activity;GO:0032947//protein complex scaffold",K05629//Tight junction;K05631//Tight junction;K06112//Tight junction
23287,0,0,0,34,33,0,0,0,49,0,0,0,AGTPBP1;ATP/GTP binding protein 1,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0060041//retina development in camera-type eye;GO:0042133//neurotransmitter metabolic process;GO:0007005//mitochondrion organization;GO:0021702//cerebellar Purkinje cell differentiation;GO:0035610//protein side chain deglutamylation;GO:0050905//neuromuscular process;GO:0021772//olfactory bulb development;GO:0035609//C-terminal protein deglutamylation;GO:0007628//adult walking behavior;GO:0001754//eye photoreceptor cell differentiation;GO:0006508//proteolysis,GO:0004181//metallocarboxypeptidase activity;GO:0015631//tubulin binding;GO:0008270//zinc ion binding,-
23288,1,1,1,0,0,0,24,114,70,0,0,766,IQCE;IQ motif containing E,GO:0005739//mitochondrion,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
23291,110,0,0,28,178,0,0,79,11,1,12,219,FBXW11;F-box and WD repeat domain containing 11,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005813//centrosome;GO:0019005//SCF ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex,"GO:0000209//protein polyubiquitination;GO:0006470//protein dephosphorylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045862//positive regulation of proteolysis;GO:0016567//protein ubiquitination;GO:0031648//protein destabilization;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0042753//positive regulation of circadian rhythm;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0016055//Wnt signaling pathway",GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity,K03362//Hedgehog signaling pathway;Oocyte meiosis;Wnt signaling pathway;Circadian rhythm - mammal;Shigellosis;Ubiquitin mediated proteolysis
23293,70,0,8,16,39,21,103,0,57,25,0,139,SMG6;SMG6 nonsense mediated mRNA decay factor,"GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0005697//telomerase holoenzyme complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region","GO:0010467//gene expression;GO:0035303//regulation of dephosphorylation;GO:0000723//telomere maintenance;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006406//mRNA export from nucleus",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004521//endoribonuclease activity;GO:0042162//telomeric DNA binding,K11124//mRNA surveillance pathway
23294,0,16,0,11,3,21,4,185,42,0,0,0,ANKS1A;ankyrin repeat and sterile alpha motif domain containing 1A,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0043005//neuron projection,GO:0048013//ephrin receptor signaling pathway;GO:0006929//substrate-dependent cell migration;GO:0016322//neuron remodeling,GO:0005515//protein binding;GO:0046875//ephrin receptor binding,-
23295,79,5,42,8,45,33,9,45,34,1,30,0,"MGRN1;mahogunin ring finger 1, E3 ubiquitin protein ligase",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005829//cytosol,GO:0043951//negative regulation of cAMP-mediated signaling;GO:0008333//endosome to lysosome transport;GO:0000209//protein polyubiquitination;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0006513//protein monoubiquitination,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K10604//Ubiquitin mediated proteolysis
23299,31,1,0,14,78,61,16,2,30,0,1,0,BICD2;bicaudal D homolog 2 (Drosophila),GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle,GO:0072393//microtubule anchoring at microtubule organizing center;GO:0008219//cell death;GO:0072385//minus-end-directed organelle transport along microtubule,GO:0005515//protein binding;GO:0017137//Rab GTPase binding,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
2330,0,0,0,10,0,0,0,0,5,0,27,0,FMO5;flavin containing monooxygenase 5,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,"GO:0050661//NADP binding;GO:0004499//N,N-dimethylaniline monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding",K00485//Methane metabolism;Drug metabolism - cytochrome P450;Microbial metabolism in diverse environments
23301,0,25,13,56,82,23,15,0,103,0,0,0,EHBP1;EH domain binding protein 1,GO:0016020//membrane;GO:0005737//cytoplasm,-,-,K06115//Tight junction;K05699//Regulation of actin cytoskeleton;Systemic lupus erythematosus;Focal adhesion;Amoebiasis;Adherens junction;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration
23302,68,0,22,0,0,2,0,0,82,1,8,0,WSCD1;WSC domain containing 1,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0008146//sulfotransferase activity,K00771//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
23303,0,55,0,50,231,13,32,41,123,0,0,0,KIF13B;kinesin family member 13B,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0030424//axon;GO:0005871//kinesin complex,GO:0007018//microtubule-based movement;GO:0042110//T cell activation;GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0050770//regulation of axonogenesis;GO:0006605//protein targeting,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding;GO:0071889//14-3-3 protein binding,-
23304,59,32,0,16,71,29,0,126,77,0,5,0,UBR2;ubiquitin protein ligase E3 component n-recognin 2,GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0000785//chromatin;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0071233//cellular response to leucine;GO:0032007//negative regulation of TOR signaling;GO:0006342//chromatin silencing;GO:0033522//histone H2A ubiquitination;GO:0007141//male meiosis I;GO:0007283//spermatogenesis,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0070728//leucine binding,-
23305,0,0,0,0,0,13,0,0,34,0,0,178,ACSL6;acyl-CoA synthetase long-chain family member 6,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane;GO:0005886//plasma membrane;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:0044255//cellular lipid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0048666//neuron development;GO:0044281//small molecule metabolic process;GO:0009629//response to gravity;GO:0032869//cellular response to insulin stimulus;GO:0010747//positive regulation of plasma membrane long-chain fatty acid transport;GO:0019432//triglyceride biosynthetic process;GO:0007405//neuroblast proliferation;GO:0006637//acyl-CoA metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0010976//positive regulation of neuron projection development;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0001666//response to hypoxia;GO:0007584//response to nutrient;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0048545//response to steroid hormone;GO:0015908//fatty acid transport,GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity,K01897//Ribosome;Peroxisome;Fatty acid metabolism;Metabolic pathways;PPAR signaling pathway;Adipocytokine signaling pathway
23306,0,1,0,0,14,0,0,0,48,0,0,0,TMEM194A;transmembrane protein 194A,GO:0016021//integral component of membrane,-,-,-
23307,0,68,1,13,13,13,0,2,21,0,0,0,"FKBP15;FK506 binding protein 15, 133kDa",GO:0030426//growth cone;GO:0005884//actin filament;GO:0030424//axon;GO:0005769//early endosome;GO:0016020//membrane,GO:0010923//negative regulation of phosphatase activity;GO:0006897//endocytosis;GO:0006457//protein folding,GO:0003779//actin binding,K12478//Endocytosis;Phagosome;Tuberculosis
23308,0,0,0,0,0,14,0,0,3,140,12,0,ICOSLG;inducible T-cell co-stimulator ligand,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006952//defense response;GO:0006972//hyperosmotic response;GO:0031295//T cell costimulation;GO:0042113//B cell activation;GO:0042104//positive regulation of activated T cell proliferation;GO:0042110//T cell activation;GO:0007165//signal transduction,GO:0005102//receptor binding,K06710//Cell adhesion molecules (CAMs);Intestinal immune network for IgA production
23309,0,0,0,1,34,0,12,32,49,82,37,0,SIN3B;SIN3 transcription regulator family member B,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000805//X chromosome;GO:0030849//autosome;GO:0000806//Y chromosome;GO:0001741//XY body,"GO:0044255//cellular lipid metabolic process;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007519//skeletal muscle tissue development;GO:0048738//cardiac muscle tissue development;GO:0044281//small molecule metabolic process",GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity,K11644//Transcriptional misregulation in cancer;Huntington's disease
2331,0,26,1,1,15,0,11,0,13,0,0,0,FMOD;fibromodulin,GO:0031012//extracellular matrix;GO:0043202//lysosomal lumen;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0018146//keratan sulfate biosynthetic process;GO:0030198//extracellular matrix organization;GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0042340//keratan sulfate catabolic process,-,-
23310,105,60,8,106,376,18,26,72,33,1,25,0,"NCAPD3;non-SMC condensin II complex, subunit D3",GO:0005654//nucleoplasm;GO:0042585//germinal vesicle;GO:0031618//nuclear pericentric heterochromatin;GO:0000799//nuclear condensin complex;GO:0016020//membrane,GO:0007076//mitotic chromosome condensation;GO:0000278//mitotic cell cycle,GO:0005515//protein binding;GO:0035064//methylated histone binding,-
23312,138,12,0,10,59,41,26,1,61,0,24,0,DMXL2;Dmx-like 2,GO:0008021//synaptic vesicle;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane,-,GO:0017137//Rab GTPase binding,K12602//RNA degradation;K12662//Spliceosome
23313,71,32,0,2,47,0,9,0,11,0,13,0,KIAA0930;KIAA0930,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer
23314,33,0,45,13,42,7,46,0,30,124,0,0,SATB2;SATB homeobox 2,GO:0005730//nucleolus;GO:0000118//histone deacetylase complex;GO:0005667//transcription factor complex;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0051216//cartilage development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002076//osteoblast development;GO:0060021//palate development;GO:0071310//cellular response to organic substance;GO:0048704//embryonic skeletal system morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009880//embryonic pattern specification;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0001764//neuron migration",GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
23315,0,2,0,0,0,25,22,0,76,0,7,0,"SLC9A8;solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0071805//potassium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0006811//ion transport;GO:1902600//hydrogen ion transmembrane transport,GO:0015386//potassium:proton antiporter activity;GO:0015385//sodium:proton antiporter activity,-
23316,210,35,22,42,112,31,7,5,71,0,4,1,CUX2;cut-like homeobox 2,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0007614//short-term memory;GO:0050890//cognition;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0071310//cellular response to organic substance;GO:0010628//positive regulation of gene expression;GO:0050775//positive regulation of dendrite morphogenesis;GO:0051965//positive regulation of synapse assembly",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding,-
23317,114,2,4,64,201,34,44,1,159,37,0,0,"DNAJC13;DnaJ (Hsp40) homolog, subfamily C, member 13",GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0001649//osteoblast differentiation,-,-
23318,93,40,1,8,86,0,15,0,9,0,0,0,"ZCCHC11;zinc finger, CCHC domain containing 11",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005615//extracellular space,GO:0010587//miRNA catabolic process;GO:0031123//RNA 3'-end processing;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0001816//cytokine production;GO:0019827//stem cell maintenance;GO:0071044//histone mRNA catabolic process;GO:0031054//pre-miRNA processing;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0010586//miRNA metabolic process,GO:0050265//RNA uridylyltransferase activity;GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
2332,0,38,0,45,106,0,0,0,31,0,4,0,FMR1;fragile X mental retardation 1,GO:0005654//nucleoplasm;GO:0042788//polysomal ribosome;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0016020//membrane;GO:0005845//mRNA cap binding complex;GO:0045202//synapse;GO:0043198//dendritic shaft;GO:0010494//cytoplasmic stress granule;GO:0005730//nucleolus,GO:0045947//negative regulation of translational initiation;GO:0051028//mRNA transport;GO:0007417//central nervous system development,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003729//mRNA binding,K15516//RNA transport
23321,14,22,1,50,274,30,41,0,66,69,16,0,TRIM2;tripartite motif containing 2,GO:0005737//cytoplasm,GO:0008219//cell death;GO:0043523//regulation of neuron apoptotic process;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
23322,164,0,0,1,5,7,83,0,75,0,3,0,RPGRIP1L;RPGRIP1-like,GO:0005930//axoneme;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005911//cell-cell junction;GO:0036064//ciliary basal body;GO:0005929//cilium;GO:0005923//tight junction,GO:0021549//cerebellum development;GO:0001701//in utero embryonic development;GO:0001889//liver development;GO:0043010//camera-type eye development;GO:0001822//kidney development;GO:0035116//embryonic hindlimb morphogenesis;GO:0060322//head development;GO:0043584//nose development;GO:0021532//neural tube patterning;GO:0008589//regulation of smoothened signaling pathway;GO:0007163//establishment or maintenance of cell polarity;GO:0022038//corpus callosum development;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0060039//pericardium development;GO:0021670//lateral ventricle development;GO:0007368//determination of left/right symmetry;GO:0021772//olfactory bulb development;GO:0035115//embryonic forelimb morphogenesis;GO:0042384//cilium assembly,GO:0005515//protein binding;GO:0031870//thromboxane A2 receptor binding,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
23324,69,0,0,0,0,46,0,10,26,0,4,0,"MAN2B2;mannosidase, alpha, class 2B, member 2",GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome,GO:0006013//mannose metabolic process,GO:0004559//alpha-mannosidase activity;GO:0008270//zinc ion binding;GO:0030246//carbohydrate binding,K12312//Other glycan degradation
23325,182,21,0,40,53,15,0,0,78,0,0,0,KIAA1033;KIAA1033,GO:0071203//WASH complex;GO:0005768//endosome,GO:0016197//endosomal transport,-,-
23326,0,9,1,68,189,37,9,0,60,0,21,0,USP22;ubiquitin specific peptidase 22,GO:0000124//SAGA complex;GO:0070461//SAGA-type complex,"GO:0016578//histone deubiquitination;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0016579//protein deubiquitination;GO:0007049//cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016574//histone ubiquitination;GO:0045931//positive regulation of mitotic cell cycle;GO:0009790//embryo development;GO:0043967//histone H4 acetylation",GO:0003713//transcription coactivator activity;GO:0019899//enzyme binding;GO:0008270//zinc ion binding;GO:0010485//H4 histone acetyltransferase activity;GO:0004843//ubiquitin-specific protease activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0005515//protein binding,-
23327,74,116,2,241,758,40,26,0,61,0,0,0,"NEDD4L;neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0086005//ventricular cardiac muscle cell action potential;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:2000009//negative regulation of protein localization to cell surface;GO:0010765//positive regulation of sodium ion transport;GO:0009651//response to salt stress;GO:2000810//regulation of tight junction assembly;GO:0006513//protein monoubiquitination;GO:0060306//regulation of membrane repolarization;GO:0010467//gene expression;GO:0006351//transcription, DNA-templated;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0016032//viral process;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0006814//sodium ion transport;GO:0003254//regulation of membrane depolarization;GO:0045807//positive regulation of endocytosis;GO:0030104//water homeostasis;GO:0019058//viral life cycle;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0010038//response to metal ion;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006883//cellular sodium ion homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0016567//protein ubiquitination;GO:2001288//positive regulation of caveolin-mediated endocytosis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0007588//excretion;GO:0034765//regulation of ion transmembrane transport;GO:0070936//protein K48-linked ubiquitination;GO:2001259//positive regulation of cation channel activity;GO:0042176//regulation of protein catabolic process;GO:0034220//ion transmembrane transport",GO:0015459//potassium channel regulator activity;GO:0017080//sodium channel regulator activity;GO:0016874//ligase activity;GO:0019870//potassium channel inhibitor activity;GO:0044325//ion channel binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019871//sodium channel inhibitor activity,K13305//Ubiquitin mediated proteolysis;Aldosterone-regulated sodium reabsorption;Endocytosis
23328,0,27,1,37,189,22,18,1,45,0,5,0,SASH1;SAM and SH3 domain containing 1,GO:0016020//membrane;GO:0043234//protein complex,GO:1900745//positive regulation of p38MAPK cascade;GO:0045766//positive regulation of angiogenesis;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0043507//positive regulation of JUN kinase activity;GO:0010595//positive regulation of endothelial cell migration;GO:0000209//protein polyubiquitination;GO:1902498//regulation of protein autoubiquitination;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:1900044//regulation of protein K63-linked ubiquitination,GO:0008022//protein C-terminus binding;GO:0032947//protein complex scaffold;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0019901//protein kinase binding,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
23329,0,30,0,0,22,11,25,0,47,0,0,0,"TBC1D30;TBC1 domain family, member 30",GO:0036064//ciliary basal body;GO:0072372//primary cilium;GO:0005886//plasma membrane,GO:0033126//positive regulation of GTP catabolic process;GO:0032851//positive regulation of Rab GTPase activity,GO:0017137//Rab GTPase binding;GO:0005097//Rab GTPase activator activity,K01691//Wnt signaling pathway
23331,0,32,0,9,48,64,20,38,102,99,61,0,TTC28;tetratricopeptide repeat domain 28,GO:0030496//midbody;GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0007067//mitotic nuclear division;GO:0007346//regulation of mitotic cell cycle,-,-
23332,0,82,1,22,53,27,0,160,24,89,11,255,CLASP1;cytoplasmic linker associated protein 1,GO:0005876//spindle microtubule;GO:0031592//centrosomal corona;GO:0005829//cytosol;GO:0030981//cortical microtubule cytoskeleton;GO:0005938//cell cortex;GO:0005813//centrosome;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005881//cytoplasmic microtubule;GO:0000776//kinetochore;GO:0005828//kinetochore microtubule;GO:0005794//Golgi apparatus,GO:0051294//establishment of spindle orientation;GO:0034453//microtubule anchoring;GO:0051301//cell division;GO:0031023//microtubule organizing center organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007411//axon guidance;GO:0000226//microtubule cytoskeleton organization;GO:0007163//establishment or maintenance of cell polarity;GO:0010458//exit from mitosis;GO:0001578//microtubule bundle formation;GO:0007020//microtubule nucleation,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0043515//kinetochore binding;GO:0051010//microtubule plus-end binding,-
23333,88,0,0,0,0,36,50,0,40,0,0,0,DPY19L1;dpy-19-like 1 (C. elegans),GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
23334,81,1153,200,644,1080,28,11,889,331,496,1288,0,SZT2;seizure threshold 2 homolog (mouse),GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome,GO:0043473//pigmentation;GO:0007417//central nervous system development;GO:0009791//post-embryonic development;GO:0009790//embryo development;GO:0021540//corpus callosum morphogenesis,-,K01816//Metabolic pathways;Glyoxylate and dicarboxylate metabolism
23335,122,15,0,47,158,19,21,0,101,0,2,0,WDR7;WD repeat domain 7,-,GO:0002244//hematopoietic progenitor cell differentiation,-,K01062//Ether lipid metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K04508//Wnt signaling pathway;K12862//Spliceosome
23336,0,0,0,1,21,0,17,0,48,162,6,0,"SYNM;synemin, intermediate filament protein",GO:0005912//adherens junction;GO:0016020//membrane;GO:0060053//neurofilament cytoskeleton;GO:0043034//costamere;GO:0005882//intermediate filament,GO:0045104//intermediate filament cytoskeleton organization,GO:0019215//intermediate filament binding;GO:0017166//vinculin binding;GO:0008307//structural constituent of muscle;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,-
23338,190,1,0,2,1,11,16,54,32,0,17,0,JADE2;jade family PHD finger 2,GO:0005634//nucleus;GO:0000123//histone acetyltransferase complex;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0043984//histone H4-K16 acetylation;GO:0043966//histone H3 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation,GO:0008270//zinc ion binding,-
2334,0,0,0,0,0,50,0,0,112,0,15,0,"AFF2;AF4/FMR2 family, member 2",GO:0016607//nuclear speck,GO:0043484//regulation of RNA splicing;GO:0007420//brain development;GO:0007611//learning or memory;GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0002151//G-quadruplex RNA binding,-
23341,0,0,0,13,19,0,27,0,69,0,15,0,"DNAJC16;DnaJ (Hsp40) homolog, subfamily C, member 16",GO:0016021//integral component of membrane,GO:0045454//cell redox homeostasis,-,-
23344,0,0,1,1,0,0,0,1,7,0,0,0,ESYT1;extended synaptotagmin-like protein 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006869//lipid transport,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008289//lipid binding,K00923//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
23345,1,1,0,0,0,44,191,79,263,0,35,1,"SYNE1;spectrin repeat containing, nuclear envelope 1",GO:0005794//Golgi apparatus;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0031965//nuclear membrane;GO:0034993//SUN-KASH complex;GO:0005730//nucleolus;GO:0005640//nuclear outer membrane;GO:0030017//sarcomere;GO:0005635//nuclear envelope;GO:0005634//nucleus,GO:0090292//nuclear matrix anchoring at nuclear membrane;GO:0040023//establishment of nucleus localization;GO:0008219//cell death;GO:0007030//Golgi organization;GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0042692//muscle cell differentiation;GO:0006997//nucleus organization,GO:0051015//actin filament binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003779//actin binding;GO:0005521//lamin binding,-
23347,18,18,1,91,247,0,40,33,105,0,16,0,SMCHD1;structural maintenance of chromosomes flexible hinge domain containing 1,GO:0001740//Barr body,GO:0051276//chromosome organization;GO:0060821//inactivation of X chromosome by DNA methylation,GO:0005524//ATP binding,-
23348,231,23,4,77,83,26,26,1,136,147,0,0,DOCK9;dedicator of cytokinesis 9,GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0032321//positive regulation of Rho GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0017048//Rho GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
23349,25,0,0,0,0,1,0,0,23,0,0,0,KIAA1045;KIAA1045,-,-,GO:0046872//metal ion binding,-
2335,0,0,0,0,46,51,16,1,130,2,12,0,FN1;fibronectin 1,GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0005577//fibrinogen complex;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016324//apical plasma membrane;GO:0005605//basal lamina;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0007155//cell adhesion;GO:0002576//platelet degranulation;GO:0010952//positive regulation of peptidase activity;GO:0007596//blood coagulation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030168//platelet activation;GO:0009611//response to wounding;GO:0050900//leukocyte migration;GO:0007044//cell-substrate junction assembly;GO:0007161//calcium-independent cell-matrix adhesion;GO:0022617//extracellular matrix disassembly;GO:0008360//regulation of cell shape;GO:0035987//endodermal cell differentiation;GO:0045773//positive regulation of axon extension;GO:0033622//integrin activation;GO:0006953//acute-phase response;GO:0001525//angiogenesis;GO:0018149//peptide cross-linking;GO:0030198//extracellular matrix organization,GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0016504//peptidase activator activity;GO:0002020//protease binding;GO:0005518//collagen binding,K05717//Pathways in cancer;Bacterial invasion of epithelial cells;ECM-receptor interaction;Regulation of actin cytoskeleton;Focal adhesion;Small cell lung cancer;Amoebiasis
23350,263,0,23,47,124,22,50,0,52,264,3,4,U2SURP;U2 snRNP-associated SURP domain containing,GO:0005634//nucleus,GO:0006396//RNA processing,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K12842//Spliceosome
23351,0,893,349,592,828,0,20,720,246,0,1121,203,KHNYN;KH and NYN domain containing,-,-,GO:0003723//RNA binding,-
23352,153,36,28,25,141,106,49,95,141,55,12,571,UBR4;ubiquitin protein ligase E3 component n-recognin 4,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0016032//viral process,GO:0005516//calmodulin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
23353,0,1,0,0,13,23,0,0,51,0,4,0,SUN1;Sad1 and UNC84 domain containing 1,GO:0034993//SUN-KASH complex;GO:0002080//acrosomal membrane;GO:0005635//nuclear envelope;GO:0005639//integral component of nuclear inner membrane,GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0006998//nuclear envelope organization;GO:0090292//nuclear matrix anchoring at nuclear membrane,GO:0005515//protein binding;GO:0005521//lamin binding,-
23354,0,0,1,0,0,9,20,0,11,0,2,0,"HAUS5;HAUS augmin-like complex, subunit 5",GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005819//spindle;GO:0070652//HAUS complex,GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization;GO:0051225//spindle assembly,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
23355,8,41,0,17,41,28,42,0,65,0,0,0,VPS8;vacuolar protein sorting 8 homolog (S. cerevisiae),-,-,GO:0008270//zinc ion binding,-
23357,0,27,0,1,0,0,10,0,41,0,0,0,ANGEL1;angel homolog 1 (Drosophila),-,-,-,K12603//RNA degradation
23358,0,3,2,51,184,49,50,0,113,0,2,0,USP24;ubiquitin specific peptidase 24,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
23359,4,0,25,0,0,0,22,45,22,0,0,0,"FAM189A1;family with sequence similarity 189, member A1",GO:0016021//integral component of membrane,-,-,-
23360,91,32,0,1,7,1,0,0,32,0,31,0,FNBP4;formin binding protein 4,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0005515//protein binding,-
23361,27,0,19,0,13,17,1,0,31,0,0,0,ZNF629;zinc finger protein 629,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23362,0,69,1,35,44,11,59,0,46,6,4,0,PSD3;pleckstrin and Sec7 domain containing 3,GO:0005802//trans-Golgi network;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0043547//positive regulation of GTPase activity;GO:0016192//vesicle-mediated transport;GO:0032012//regulation of ARF protein signal transduction;GO:0030182//neuron differentiation,GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12494//Endocytosis
23363,200,1,0,11,12,9,23,75,42,0,0,0,OBSL1;obscurin-like 1,GO:0030018//Z disc;GO:0031430//M band;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0014704//intercalated disc;GO:0005794//Golgi apparatus,GO:0007088//regulation of mitosis;GO:0007010//cytoskeleton organization;GO:0007030//Golgi organization;GO:0000226//microtubule cytoskeleton organization;GO:0055003//cardiac myofibril assembly;GO:0034067//protein localization to Golgi apparatus;GO:0050775//positive regulation of dendrite morphogenesis,GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;K00747//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways
23365,0,0,0,13,59,0,0,0,0,0,0,0,ARHGEF12;Rho guanine nucleotide exchange factor (GEF) 12,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0007411//axon guidance;GO:0007186//G-protein coupled receptor signaling pathway,GO:0001664//G-protein coupled receptor binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K07532//Tuberculosis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Axon guidance
23366,0,0,0,0,0,0,6,0,42,0,4,0,KIAA0895;KIAA0895,-,-,-,-
23367,0,98,0,29,156,22,0,0,48,0,22,0,"LARP1;La ribonucleoprotein domain family, member 1",GO:0031931//TORC1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005730//nucleolus,GO:0045727//positive regulation of translation;GO:0006413//translational initiation;GO:0016239//positive regulation of macroautophagy;GO:0008283//cell proliferation;GO:0031929//TOR signaling,GO:0000339//RNA cap binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003730//mRNA 3'-UTR binding;GO:0008190//eukaryotic initiation factor 4E binding;GO:0048027//mRNA 5'-UTR binding;GO:0008494//translation activator activity;GO:0031369//translation initiation factor binding,K11090//Systemic lupus erythematosus
23368,0,1,0,17,11,0,0,52,19,0,0,0,"PPP1R13B;protein phosphatase 1, regulatory subunit 13B",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0045786//negative regulation of cell cycle,GO:0008134//transcription factor binding;GO:0005515//protein binding,K12329//Vascular smooth muscle contraction;K06270//Focal adhesion;Long-term potentiation;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
23369,0,32,1,104,322,0,31,0,42,208,8,61,PUM2;pumilio RNA-binding family member 2,GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0010494//cytoplasmic stress granule,GO:0006417//regulation of translation;GO:0034063//stress granule assembly,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
23370,12,0,0,7,47,0,0,42,40,0,4,0,ARHGEF18;Rho/Rac guanine nucleotide exchange factor (GEF) 18,GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0030054//cell junction;GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0008360//regulation of cell shape,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12791//Pathogenic Escherichia coli infection
23371,172,91,21,67,125,38,0,294,33,0,178,0,TENC1;tensin like C1 domain containing phosphatase (tensin 2),GO:0005886//plasma membrane;GO:0005925//focal adhesion,GO:0014850//response to muscle activity;GO:0035264//multicellular organism growth;GO:0016311//dephosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0032963//collagen metabolic process;GO:0035556//intracellular signal transduction;GO:0048871//multicellular organismal homeostasis;GO:0019725//cellular homeostasis;GO:0001822//kidney development,GO:0004721//phosphoprotein phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K09526//Endocytosis;K01110//Small cell lung cancer;Prostate cancer;Tight junction;Pathways in cancer;Phosphatidylinositol signaling system;Focal adhesion;Inositol phosphate metabolism;p53 signaling pathway;Glioma;Melanoma;Endometrial cancer;K00665//Metabolic pathways;Insulin signaling pathway;Fatty acid biosynthesis
23373,1,0,0,0,0,0,8,22,94,0,15,0,CRTC1;CREB regulated transcription coactivator 1,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007613//memory;GO:0060081//membrane hyperpolarization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051289//protein homotetramerization;GO:0016032//viral process;GO:0032793//positive regulation of CREB transcription factor activity;GO:0043153//entrainment of circadian clock by photoperiod;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0008140//cAMP response element binding protein binding,K15309//HTLV-I infection
23376,0,23,0,1,3,11,0,0,42,0,0,0,UFL1;UFM1-specific ligase 1,GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0034976//response to endoplasmic reticulum stress;GO:0071569//protein ufmylation;GO:0001649//osteoblast differentiation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031397//negative regulation of protein ubiquitination,GO:0005515//protein binding;GO:0071568//UFM1 conjugating enzyme activity,-
23378,0,0,0,6,15,0,0,0,0,303,0,2,"RRP8;ribosomal RNA processing 8, methyltransferase, homolog (yeast)",GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0033553//rDNA heterochromatin;GO:0005677//chromatin silencing complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0042149//cellular response to glucose starvation;GO:0046015//regulation of transcription by glucose;GO:0000183//chromatin silencing at rDNA;GO:0071158//positive regulation of cell cycle arrest;GO:0006364//rRNA processing;GO:0032259//methylation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0016568//chromatin modification",GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0035064//methylated histone binding,-
23379,0,0,2,13,80,25,0,88,66,0,0,0,ICE1;interactor of little elongator complex ELL subunit 1,GO:0015030//Cajal body;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin,GO:0042796//snRNA transcription from RNA polymerase III promoter;GO:0031334//positive regulation of protein complex assembly;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0090316//positive regulation of intracellular protein transport,GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
23380,0,44,0,0,0,0,22,0,12,0,0,0,SRGAP2;SLIT-ROBO Rho GTPase activating protein 2,GO:0005634//nucleus;GO:0044327//dendritic spine head;GO:0005829//cytosol;GO:0030027//lamellipodium;GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0045335//phagocytic vesicle;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:2001223//negative regulation of neuron migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051014//actin filament severing;GO:0034446//substrate adhesion-dependent cell spreading;GO:0021816//extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration;GO:0046847//filopodium assembly;GO:0048812//neuron projection morphogenesis;GO:0060996//dendritic spine development;GO:0032855//positive regulation of Rac GTPase activity;GO:0008283//cell proliferation;GO:0003363//lamellipodium assembly involved in ameboidal cell migration;GO:0007411//axon guidance;GO:0060548//negative regulation of cell death,GO:0030675//Rac GTPase activator activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0048365//Rac GTPase binding,K07526//Axon guidance
23381,0,1,0,0,48,0,36,0,16,0,1,0,SMG5;SMG5 nonsense mediated mRNA decay factor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0006406//mRNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0010467//gene expression;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0035303//regulation of dephosphorylation",GO:0051721//protein phosphatase 2A binding;GO:0005515//protein binding,K11125//mRNA surveillance pathway
23382,86,1,1,13,32,8,12,0,29,0,0,0,AHCYL2;adenosylhomocysteinase-like 2,-,GO:0006730//one-carbon metabolic process,GO:0004013//adenosylhomocysteinase activity,K01251//Metabolic pathways;Cysteine and methionine metabolism
23383,0,0,0,0,0,0,15,46,28,0,11,0,MAU2;MAU2 sister chromatid cohesion factor,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0032116//SMC loading complex,GO:0000278//mitotic cell cycle;GO:0034088//maintenance of mitotic sister chromatid cohesion,GO:0047485//protein N-terminus binding;GO:0005515//protein binding,-
23384,0,0,0,11,2,0,0,75,21,0,29,0,SPECC1L;sperm antigen with calponin homology and coiled-coil domains 1-like,GO:0031941//filamentous actin;GO:0005737//cytoplasm;GO:0005921//gap junction;GO:0005819//spindle;GO:0005815//microtubule organizing center,GO:0030835//negative regulation of actin filament depolymerization;GO:0007026//negative regulation of microtubule depolymerization;GO:0007049//cell cycle;GO:0051301//cell division;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization,-,K05699//Regulation of actin cytoskeleton;Systemic lupus erythematosus;Focal adhesion;Amoebiasis;Adherens junction;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration;K06115//Tight junction;K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
23385,0,0,0,0,13,0,57,0,51,0,7,0,NCSTN;nicastrin,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0005765//lysosomal membrane;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0031293//membrane protein intracellular domain proteolysis;GO:0006508//proteolysis;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0007219//Notch signaling pathway;GO:0022617//extracellular matrix disassembly;GO:0016485//protein processing;GO:0050435//beta-amyloid metabolic process;GO:0007220//Notch receptor processing;GO:0006509//membrane protein ectodomain proteolysis;GO:0050673//epithelial cell proliferation;GO:0002262//myeloid cell homeostasis;GO:0042098//T cell proliferation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030198//extracellular matrix organization,GO:0005515//protein binding;GO:0004175//endopeptidase activity,K06171//Alzheimer's disease;Notch signaling pathway
23386,0,1,1,0,14,49,20,0,32,0,13,0,NUDCD3;NudC domain containing 3,-,-,GO:0005515//protein binding,-
23387,0,1,0,7,45,16,0,0,38,0,0,0,SIK3;SIK family kinase 3,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,-
23389,135,53,1,32,133,0,0,2,32,0,0,0,MED13L;mediator complex subunit 13-like,GO:0016592//mediator complex,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0001104//RNA polymerase II transcription cofactor activity,-
2339,0,13,1,11,63,0,0,0,18,0,3,0,"FNTA;farnesyltransferase, CAAX box, alpha",GO:0005953//CAAX-protein geranylgeranyltransferase complex;GO:0005737//cytoplasm;GO:0005965//protein farnesyltransferase complex;GO:0005829//cytosol;GO:0005875//microtubule associated complex,"GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0018343//protein farnesylation;GO:0018344//protein geranylgeranylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0090045//positive regulation of deacetylase activity;GO:0090044//positive regulation of tubulin deacetylation;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0006915//apoptotic process;GO:0007603//phototransduction, visible light",GO:0004662//CAAX-protein geranylgeranyltransferase activity;GO:0004660//protein farnesyltransferase activity;GO:0008017//microtubule binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding,K05955//Terpenoid backbone biosynthesis
23390,11,0,0,0,1,1,1,0,35,24,0,0,"ZDHHC17;zinc finger, DHHC-type containing 17",GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0030660//Golgi-associated vesicle membrane;GO:0005737//cytoplasm,GO:0018345//protein palmitoylation;GO:0015693//magnesium ion transport;GO:0042953//lipoprotein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0015095//magnesium ion transmembrane transporter activity;GO:0042802//identical protein binding,K11420//Lysine degradation
23392,200,89,1,45,235,25,37,1,147,0,26,495,KIAA0368;KIAA0368,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005813//centrosome;GO:0005802//trans-Golgi network;GO:0000502//proteasome complex;GO:0005769//early endosome;GO:0030134//ER to Golgi transport vesicle;GO:0005783//endoplasmic reticulum;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016020//membrane;GO:0005770//late endosome;GO:0005634//nucleus;GO:0005771//multivesicular body;GO:0030139//endocytic vesicle,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,-,-
23394,0,0,1,46,201,7,25,0,74,0,0,0,ADNP;activity-dependent neuroprotector homeobox,GO:0005634//nucleus;GO:0005615//extracellular space,"GO:0006351//transcription, DNA-templated;GO:0043524//negative regulation of neuron apoptotic process;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
23395,0,17,0,0,7,0,4,0,54,1,18,26,"LARS2;leucyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0006450//regulation of translational fidelity;GO:0006429//leucyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004823//leucine-tRNA ligase activity,K01869//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Cyanoamino acid metabolism;Riboflavin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;ABC transporters
23396,0,0,0,5,1,0,14,0,43,0,0,0,"PIP5K1C;phosphatidylinositol-4-phosphate 5-kinase, type I, gamma",GO:0005634//nucleus;GO:0001931//uropod;GO:0005925//focal adhesion;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0001891//phagocytic cup,GO:0030036//actin cytoskeleton organization;GO:0034333//adherens junction assembly;GO:0030593//neutrophil chemotaxis;GO:0072583//clathrin-mediated endocytosis;GO:0048488//synaptic vesicle endocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0016337//single organismal cell-cell adhesion;GO:0007411//axon guidance;GO:0070527//platelet aggregation;GO:0006644//phospholipid metabolic process;GO:0006909//phagocytosis;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0044281//small molecule metabolic process,GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:1990147//talin binding,K00889//Phosphatidylinositol signaling system;Endocytosis;Metabolic pathways;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Inositol phosphate metabolism;Focal adhesion
23397,0,0,0,0,0,0,1,20,22,0,17,302,"NCAPH;non-SMC condensin I complex, subunit H",GO:0000796//condensin complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton,GO:0007076//mitotic chromosome condensation;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K06676//Cell cycle - yeast
23398,0,36,0,0,0,0,14,0,18,0,0,0,PPWD1;peptidylprolyl isomerase domain and WD repeat containing 1,GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus,"GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization",GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
23399,0,10,0,6,30,5,0,0,13,0,24,0,CTDNEP1;CTD nuclear envelope phosphatase 1,GO:0005789//endoplasmic reticulum membrane;GO:0071595//Nem1-Spo7 phosphatase complex;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0034504//protein localization to nucleus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0006470//protein dephosphorylation;GO:0007276//gamete generation;GO:0006998//nuclear envelope organization;GO:0007498//mesoderm development,GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,-
23400,131,0,0,0,6,29,17,63,47,1,6,0,ATP13A2;ATPase type 13A2,GO:0005765//lysosomal membrane;GO:0005764//lysosome;GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process;GO:0008219//cell death;GO:0071287//cellular response to manganese ion,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019829//cation-transporting ATPase activity;GO:0005524//ATP binding,-
23401,0,11,0,3,7,22,0,0,11,0,0,0,FRAT2;frequently rearranged in advanced T-cell lymphomas 2,-,GO:0016055//Wnt signaling pathway;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation,-,K03096//Wnt signaling pathway;K03069//Wnt signaling pathway
23403,0,0,0,0,0,0,0,1,13,49,0,0,FBXO46;F-box protein 46,-,-,GO:0005515//protein binding,-
23404,0,0,0,16,13,19,0,0,4,0,3,96,EXOSC2;exosome component 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000178//exosome (RNase complex);GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006364//rRNA processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0030307//positive regulation of cell growth;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0008312//7S RNA binding;GO:0004532//exoribonuclease activity;GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity,K03679//RNA degradation
23405,0,45,0,58,142,14,72,35,111,40,29,0,"DICER1;dicer 1, ribonuclease type III",GO:0005829//cytosol;GO:0030425//dendrite;GO:0030424//axon;GO:0016442//RISC complex;GO:0030426//growth cone;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,"GO:0071335//hair follicle cell proliferation;GO:0048812//neuron projection morphogenesis;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0031069//hair follicle morphogenesis;GO:0032290//peripheral nervous system myelin formation;GO:0031643//positive regulation of myelination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021889//olfactory bulb interneuron differentiation;GO:0035264//multicellular organism growth;GO:0055013//cardiac muscle cell development;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0051607//defense response to virus;GO:2000630//positive regulation of miRNA metabolic process;GO:0010070//zygote asymmetric cell division;GO:0014040//positive regulation of Schwann cell differentiation;GO:0070173//regulation of enamel mineralization;GO:0031054//pre-miRNA processing;GO:0030324//lung development;GO:0048536//spleen development;GO:0060119//inner ear receptor cell development;GO:0001525//angiogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0045664//regulation of neuron differentiation;GO:0045069//regulation of viral genome replication;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0010626//negative regulation of Schwann cell proliferation;GO:0048608//reproductive structure development;GO:0051726//regulation of cell cycle;GO:0060576//intestinal epithelial cell development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0021522//spinal cord motor neuron differentiation;GO:0009791//post-embryonic development;GO:0051225//spindle assembly;GO:0048255//mRNA stabilization;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0019827//stem cell maintenance;GO:0021675//nerve development;GO:0021987//cerebral cortex development;GO:0030422//production of siRNA involved in RNA interference;GO:0048713//regulation of oligodendrocyte differentiation",GO:0005524//ATP binding;GO:0004525//ribonuclease III activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004386//helicase activity;GO:0035198//miRNA binding;GO:0003725//double-stranded RNA binding,-
23406,0,0,1,0,8,0,0,0,0,0,0,0,COTL1;coactosin-like F-actin binding protein 1,GO:0031965//nuclear membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0050832//defense response to fungus,GO:0005515//protein binding;GO:0003779//actin binding;GO:0019899//enzyme binding,-
23408,0,0,0,11,76,0,4,9,40,6,29,0,SIRT5;sirtuin 5,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005758//mitochondrial intermembrane space;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0006342//chromatin silencing;GO:0036049//peptidyl-lysine desuccinylation;GO:0036047//peptidyl-lysine demalonylation;GO:0006476//protein deacetylation;GO:0006471//protein ADP-ribosylation;GO:2000378//negative regulation of reactive oxygen species metabolic process,GO:0070403//NAD+ binding;GO:0008270//zinc ion binding;GO:0036055//protein-succinyllysine desuccinylase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0036054//protein-malonyllysine demalonylase activity,-
23410,4,17,28,23,49,0,25,1,14,0,15,0,SIRT3;sirtuin 3,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0006476//protein deacetylation;GO:0070932//histone H3 deacetylation;GO:0009060//aerobic respiration;GO:0006471//protein ADP-ribosylation;GO:0034983//peptidyl-lysine deacetylation,GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0070403//NAD+ binding;GO:0008270//zinc ion binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0005515//protein binding,-
23411,0,24,0,9,42,25,3,49,40,0,0,0,SIRT1;sirtuin 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0035098//ESC/E(Z) complex;GO:0005720//nuclear heterochromatin;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005677//chromatin silencing complex;GO:0005739//mitochondrion;GO:0005719//nuclear euchromatin;GO:0033553//rDNA heterochromatin;GO:0016605//PML body;GO:0005730//nucleolus;GO:0005637//nuclear inner membrane,"GO:0002821//positive regulation of adaptive immune response;GO:0050872//white fat cell differentiation;GO:0007346//regulation of mitotic cell cycle;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0001678//cellular glucose homeostasis;GO:0031937//positive regulation of chromatin silencing;GO:0006260//DNA replication;GO:0006476//protein deacetylation;GO:0031648//protein destabilization;GO:0000012//single strand break repair;GO:0042326//negative regulation of phosphorylation;GO:0032007//negative regulation of TOR signaling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032868//response to insulin;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0034983//peptidyl-lysine deacetylation;GO:0006364//rRNA processing;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045599//negative regulation of fat cell differentiation;GO:0032922//circadian regulation of gene expression;GO:0006346//methylation-dependent chromatin silencing;GO:0001542//ovulation from ovarian follicle;GO:0071356//cellular response to tumor necrosis factor;GO:0034391//regulation of smooth muscle cell apoptotic process;GO:0009267//cellular response to starvation;GO:0070857//regulation of bile acid biosynthetic process;GO:0031393//negative regulation of prostaglandin biosynthetic process;GO:0042127//regulation of cell proliferation;GO:2000655//negative regulation of cellular response to testosterone stimulus;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0007283//spermatogenesis;GO:0006979//response to oxidative stress;GO:0006642//triglyceride mobilization;GO:0035358//regulation of peroxisome proliferator activated receptor signaling pathway;GO:2000773//negative regulation of cellular senescence;GO:0008284//positive regulation of cell proliferation;GO:0042542//response to hydrogen peroxide;GO:0030308//negative regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1901215//negative regulation of neuron death;GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0006281//DNA repair;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0016239//positive regulation of macroautophagy;GO:0051097//negative regulation of helicase activity;GO:0000183//chromatin silencing at rDNA;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0010875//positive regulation of cholesterol efflux;GO:0043065//positive regulation of apoptotic process;GO:0018394//peptidyl-lysine acetylation;GO:0006342//chromatin silencing;GO:0000731//DNA synthesis involved in DNA repair;GO:0007569//cell aging;GO:0055089//fatty acid homeostasis;GO:0071456//cellular response to hypoxia;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0006471//protein ADP-ribosylation;GO:0070932//histone H3 deacetylation;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:2000757//negative regulation of peptidyl-lysine acetylation;GO:0033158//regulation of protein import into nucleus, translocation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0016567//protein ubiquitination;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0032071//regulation of endodeoxyribonuclease activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045739//positive regulation of DNA repair;GO:0070301//cellular response to hydrogen peroxide;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:0016032//viral process;GO:0051898//negative regulation of protein kinase B signaling;GO:0007517//muscle organ development;GO:0001934//positive regulation of protein phosphorylation;GO:0010906//regulation of glucose metabolic process;GO:2000774//positive regulation of cellular senescence;GO:0042632//cholesterol homeostasis;GO:0016575//histone deacetylation;GO:0006344//maintenance of chromatin silencing;GO:2000111//positive regulation of macrophage apoptotic process;GO:0001525//angiogenesis;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0071479//cellular response to ionizing radiation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035356//cellular triglyceride homeostasis;GO:0006351//transcription, DNA-templated;GO:0006343//establishment of chromatin silencing",GO:0046872//metal ion binding;GO:0019213//deacetylase activity;GO:0002039//p53 binding;GO:0043425//bHLH transcription factor binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0034979//NAD-dependent protein deacetylase activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0017136//NAD-dependent histone deacetylase activity;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0070403//NAD+ binding;GO:0043398//HLH domain binding;GO:0004407//histone deacetylase activity;GO:0019899//enzyme binding;GO:0051019//mitogen-activated protein kinase binding;GO:1990254//keratin filament binding;GO:0033558//protein deacetylase activity;GO:0003714//transcription corepressor activity,K11411//Amphetamine addiction
23412,0,0,0,7,8,0,0,0,0,0,0,0,COMMD3;COMM domain containing 3,-,-,GO:0005515//protein binding,K11459//Transcriptional misregulation in cancer
23413,0,0,0,0,6,0,4,64,84,4,22,0,NCS1;neuronal calcium sensor 1,GO:0048471//perinuclear region of cytoplasm;GO:0030424//axon;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0032580//Golgi cisterna membrane;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane,GO:0070588//calcium ion transmembrane transport;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045921//positive regulation of exocytosis;GO:0010975//regulation of neuron projection development,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0019901//protein kinase binding;GO:0000287//magnesium ion binding,K13764//Phototransduction
23414,0,0,0,0,0,34,0,65,39,0,0,0,"ZFPM2;zinc finger protein, FOG family member 2",GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0045599//negative regulation of fat cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048568//embryonic organ development;GO:0006351//transcription, DNA-templated;GO:0001570//vasculogenesis;GO:0001701//in utero embryonic development;GO:0060548//negative regulation of cell death;GO:0007596//blood coagulation;GO:0003221//right ventricular cardiac muscle tissue morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:2000020//positive regulation of male gonad development;GO:2000195//negative regulation of female gonad development;GO:0007506//gonadal mesoderm development;GO:0060412//ventricular septum morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003714//transcription corepressor activity;GO:0001071//nucleic acid binding transcription factor activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0005515//protein binding,-
23415,0,0,31,0,0,0,0,0,42,0,26,0,"KCNH4;potassium voltage-gated channel, subfamily H (eag-related), member 4",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0000160//phosphorelay signal transduction system;GO:0034765//regulation of ion transmembrane transport;GO:0023014//signal transduction by phosphorylation;GO:0007268//synaptic transmission;GO:0042391//regulation of membrane potential;GO:0006813//potassium ion transport,GO:0000155//phosphorelay sensor kinase activity;GO:0005249//voltage-gated potassium channel activity,-
23416,0,0,0,0,0,0,15,10,5,4,0,0,"KCNH3;potassium voltage-gated channel, subfamily H (eag-related), member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0042391//regulation of membrane potential;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0023014//signal transduction by phosphorylation;GO:0071805//potassium ion transmembrane transport;GO:0000160//phosphorelay signal transduction system;GO:0006813//potassium ion transport,GO:0000155//phosphorelay sensor kinase activity;GO:0005249//voltage-gated potassium channel activity;GO:0005515//protein binding,-
23417,0,8,1,9,36,5,0,0,21,0,0,0,MLYCD;malonyl-CoA decarboxylase,GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0044255//cellular lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006085//acetyl-CoA biosynthetic process;GO:0002931//response to ischemia;GO:0046321//positive regulation of fatty acid oxidation;GO:0010906//regulation of glucose metabolic process;GO:2001294//malonyl-CoA catabolic process,GO:0050080//malonyl-CoA decarboxylase activity;GO:0005102//receptor binding,K01578//Peroxisome;Metabolic pathways;beta-Alanine metabolism;Propanoate metabolism
23418,0,0,0,0,0,11,19,0,26,0,5,48,"CRB1;crumbs family member 1, photoreceptor morphogenesis associated",GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005902//microvillus;GO:0016324//apical plasma membrane,GO:0007163//establishment or maintenance of cell polarity;GO:0042462//eye photoreceptor cell development;GO:0007009//plasma membrane organization;GO:0007267//cell-cell signaling,GO:0005509//calcium ion binding;GO:0005515//protein binding,K02599//Dorso-ventral axis formation;Notch signaling pathway;Prion diseases
2342,0,0,46,8,2,0,0,0,0,0,0,0,"FNTB;farnesyltransferase, CAAX box, beta",GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0005965//protein farnesyltransferase complex,"GO:0045787//positive regulation of cell cycle;GO:0010035//response to inorganic substance;GO:0014070//response to organic cyclic compound;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0018343//protein farnesylation;GO:0007603//phototransduction, visible light;GO:0042060//wound healing;GO:0034097//response to cytokine;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0048146//positive regulation of fibroblast proliferation",GO:0004311//farnesyltranstransferase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004660//protein farnesyltransferase activity,K05954//Terpenoid backbone biosynthesis
23420,0,0,0,0,1,0,31,37,3,0,0,0,NOMO1;NODAL modulator 1,GO:0016021//integral component of membrane;GO:0016020//membrane,-,GO:0030246//carbohydrate binding,-
23424,0,0,1,0,15,24,47,0,46,0,0,0,TDRD7;tudor domain containing 7,GO:0033391//chromatoid body;GO:0043186//P granule;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0010608//posttranscriptional regulation of gene expression;GO:0007281//germ cell development;GO:0007283//spermatogenesis;GO:0070306//lens fiber cell differentiation;GO:0002089//lens morphogenesis in camera-type eye,GO:0047485//protein N-terminus binding;GO:0003729//mRNA binding;GO:0005515//protein binding,K15979//Epstein-Barr virus infection
23426,0,0,0,14,0,32,0,3,7,0,0,0,GRIP1;glutamate receptor interacting protein 1,GO:0005829//cytosol;GO:0055037//recycling endosome;GO:0045211//postsynaptic membrane;GO:0045121//membrane raft;GO:0043005//neuron projection;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030054//cell junction,"GO:0008104//protein localization;GO:0007268//synaptic transmission;GO:0035556//intracellular signal transduction;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding;GO:0030159//receptor signaling complex scaffold activity;GO:0050681//androgen receptor binding;GO:0005515//protein binding,K06095//Tight junction
23428,84,4,1,11,37,0,0,93,63,0,0,0,"SLC7A8;solute carrier family 7 (amino acid transporter light chain, L system), member 8",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,GO:0050900//leukocyte migration;GO:0009636//response to toxic substance;GO:0006865//amino acid transport;GO:0015695//organic cation transport;GO:0055085//transmembrane transport;GO:0055065//metal ion homeostasis;GO:1901998//toxin transport;GO:0006520//cellular amino acid metabolic process;GO:0015804//neutral amino acid transport;GO:0006810//transport;GO:0007596//blood coagulation;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0006811//ion transport,GO:0015171//amino acid transmembrane transporter activity;GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0019534//toxin transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity,K13781//Protein digestion and absorption
23429,174,6,0,32,132,9,0,0,48,0,12,0,RYBP;RING1 and YY1 binding protein,GO:0031519//PcG protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035518//histone H2A monoubiquitination;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process",GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
23430,0,0,0,0,0,0,13,0,19,0,0,0,TPSD1;tryptase delta 1,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
23431,0,0,0,1,0,53,16,4,23,0,8,0,"AP4E1;adaptor-related protein complex 4, epsilon 1 subunit",GO:0005905//coated pit;GO:0005794//Golgi apparatus;GO:0030117//membrane coat,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,-,K12400//Lysosome
23432,0,0,0,4,0,0,0,99,6,0,0,1,GPR161;G protein-coupled receptor 161,GO:0016021//integral component of membrane;GO:0072372//primary cilium;GO:0060170//ciliary membrane;GO:0055037//recycling endosome,GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007275//multicellular organismal development;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
23433,0,122,13,121,250,47,24,62,89,0,7,0,RHOQ;ras homolog family member Q,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0005884//actin filament,GO:0051491//positive regulation of filopodium assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0032869//cellular response to insulin stimulus;GO:0006184//GTP catabolic process;GO:0046326//positive regulation of glucose import;GO:0030866//cortical actin cytoskeleton organization;GO:0008286//insulin receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0008360//regulation of cell shape,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005522//profilin binding;GO:0032427//GBD domain binding,K07194//Insulin signaling pathway
23435,101,0,0,86,204,9,25,0,12,0,0,0,TARDBP;TAR DNA binding protein,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0008219//cell death;GO:0043922//negative regulation by host of viral transcription;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0070935//3'-UTR-mediated mRNA stabilization,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003730//mRNA 3'-UTR binding;GO:0003690//double-stranded DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0042802//identical protein binding;GO:0003723//RNA binding,K14411//mRNA surveillance pathway
23438,18,0,2,0,20,0,0,0,42,0,0,210,"HARS2;histidyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0006412//translation;GO:0006427//histidyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0004821//histidine-tRNA ligase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,K01892//Aminoacyl-tRNA biosynthesis;Ribosome
23439,30,0,0,0,1,0,0,0,58,0,0,45,"ATP1B4;ATPase, Na+/K+ transporting, beta 4 polypeptide",GO:0005887//integral component of plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005637//nuclear inner membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0015672//monovalent inorganic cation transport;GO:0006810//transport",GO:0015077//monovalent inorganic cation transmembrane transporter activity,K01540//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
23440,0,0,0,0,0,13,0,0,3,0,0,0,OTP;orthopedia homeobox,GO:0005634//nucleus,"GO:0021979//hypothalamus cell differentiation;GO:0021985//neurohypophysis development;GO:0006355//regulation of transcription, DNA-templated;GO:0002052//positive regulation of neuroblast proliferation;GO:0021879//forebrain neuron differentiation;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
23443,0,18,2,18,17,21,0,8,42,0,51,1,"SLC35A3;solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0055085//transmembrane transport;GO:1901679//nucleotide transmembrane transport;GO:0006047//UDP-N-acetylglucosamine metabolic process;GO:0008643//carbohydrate transport;GO:0015788//UDP-N-acetylglucosamine transport;GO:0015992//proton transport,GO:0005351//sugar:proton symporter activity;GO:0005515//protein binding;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity,-
23446,0,0,1,9,7,43,0,0,69,0,10,0,"SLC44A1;solute carrier family 44 (choline transporter), member 1",GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006656//phosphatidylcholine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0055085//transmembrane transport;GO:0006644//phospholipid metabolic process;GO:0015871//choline transport;GO:0046474//glycerophospholipid biosynthetic process,GO:0015220//choline transmembrane transporter activity,-
23450,2,15,0,70,66,58,53,0,84,212,28,0,"SF3B3;splicing factor 3b, subunit 3, 130kDa",GO:0005689//U12-type spliceosomal complex;GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm,"GO:0006461//protein complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing",GO:0003676//nucleic acid binding,K12830//Spliceosome
23451,0,172,1,71,291,36,0,0,54,1,0,0,"SF3B1;splicing factor 3b, subunit 1, 155kDa",GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0016607//nuclear speck,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0009952//anterior/posterior pattern specification",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003682//chromatin binding,K12828//Spliceosome
23452,75,0,0,0,0,1,0,0,7,0,13,0,ANGPTL2;angiopoietin-like 2,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0007275//multicellular organismal development,GO:0005102//receptor binding,-
23456,0,0,0,1,0,0,10,24,47,0,1,0,"ABCB10;ATP-binding cassette, sub-family B (MDR/TAP), member 10",GO:0032592//integral component of mitochondrial membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0006810//transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0005215//transporter activity",K05657//ABC transporters
23457,157,0,1,0,0,29,0,45,17,0,6,0,"ABCB9;ATP-binding cassette, sub-family B (MDR/TAP), member 9",GO:0005769//early endosome;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005765//lysosomal membrane;GO:0005764//lysosome,GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0015833//peptide transport;GO:0006200//ATP catabolic process;GO:0015031//protein transport;GO:0055085//transmembrane transport,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0022891//substrate-specific transmembrane transporter activity;GO:0015440//peptide-transporting ATPase activity;GO:0005524//ATP binding,K05656//ABC transporters;Lysosome
2346,0,87,1,45,118,27,0,0,52,0,0,0,FOLH1;folate hydrolase (prostate-specific membrane antigen) 1,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0006760//folic acid-containing compound metabolic process;GO:0006508//proteolysis,GO:0046872//metal ion binding;GO:0016805//dipeptidase activity;GO:0008237//metallopeptidase activity;GO:0008233//peptidase activity;GO:0004180//carboxypeptidase activity,K14592//Vitamin digestion and absorption
23460,0,0,0,0,0,31,11,0,60,0,0,0,"ABCA6;ATP-binding cassette, sub-family A (ABC1), member 6",GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process;GO:0006810//transport,GO:0005524//ATP binding;GO:0016887//ATPase activity,K05649//ABC transporters
23461,0,0,0,0,0,34,24,0,75,0,8,0,"ABCA5;ATP-binding cassette, sub-family A (ABC1), member 5",GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005770//late endosome,GO:0034375//high-density lipoprotein particle remodeling;GO:0033344//cholesterol efflux;GO:0006200//ATP catabolic process;GO:0043691//reverse cholesterol transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation,GO:0005524//ATP binding;GO:0016887//ATPase activity,K05648//ABC transporters
23462,52,0,0,0,1,0,22,68,0,0,0,0,HEY1;hes-related family bHLH transcription factor with YRPW motif 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0003190//atrioventricular valve formation;GO:0003203//endocardial cushion morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0003184//pulmonary valve morphogenesis;GO:0060716//labyrinthine layer blood vessel development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0060347//heart trabecula formation;GO:0060411//cardiac septum morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0061314//Notch signaling involved in heart development;GO:0001525//angiogenesis;GO:2001212//regulation of vasculogenesis;GO:0001570//vasculogenesis;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:0045746//negative regulation of Notch signaling pathway;GO:0002076//osteoblast development;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0006366//transcription from RNA polymerase II promoter;GO:0003208//cardiac ventricle morphogenesis;GO:0036304//umbilical cord morphogenesis;GO:0071385//cellular response to glucocorticoid stimulus;GO:0060842//arterial endothelial cell differentiation;GO:0009948//anterior/posterior axis specification;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0007219//Notch signaling pathway;GO:0060412//ventricular septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035912//dorsal aorta morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0035939//microsatellite binding;GO:0000988//protein binding transcription factor activity;GO:0008134//transcription factor binding;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0046983//protein dimerization activity,-
23463,0,46,0,0,9,0,0,2,20,0,2,0,ICMT;isoprenylcysteine carboxyl methyltransferase,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:2001141//regulation of RNA biosynthetic process;GO:0006481//C-terminal protein methylation;GO:0035264//multicellular organism growth;GO:0001889//liver development;GO:0006612//protein targeting to membrane;GO:0006464//cellular protein modification process;GO:0046578//regulation of Ras protein signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0001701//in utero embryonic development,GO:0004671//protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity;GO:0003880//protein C-terminal carboxyl O-methyltransferase activity;GO:0008140//cAMP response element binding protein binding,K00587//Terpenoid backbone biosynthesis
23464,0,1,2,4,0,9,0,0,18,0,0,2,GCAT;glycine C-acetyltransferase,GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0019518//L-threonine catabolic process to glycine;GO:0009058//biosynthetic process;GO:0006520//cellular amino acid metabolic process,GO:0008890//glycine C-acetyltransferase activity;GO:0030170//pyridoxal phosphate binding,"K00639//Glycine, serine and threonine metabolism"
23466,0,0,1,7,72,0,25,0,68,0,0,1,CBX6;chromobox homolog 6,GO:0005654//nucleoplasm;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0031519//PcG protein complex,"GO:0016568//chromatin modification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003727//single-stranded RNA binding,-
23467,0,0,0,0,0,13,22,0,93,67,5,0,NPTXR;neuronal pentraxin receptor,GO:0016021//integral component of membrane,-,GO:0046872//metal ion binding,-
23468,0,240,3,194,509,15,42,0,11,0,23,0,CBX5;chromobox homolog 5,GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0005720//nuclear heterochromatin;GO:0010369//chromocenter;GO:0000776//kinetochore;GO:0017053//transcriptional repressor complex;GO:0000118//histone deacetylase complex;GO:0005635//nuclear envelope;GO:0031618//nuclear pericentric heterochromatin;GO:0005634//nucleus;GO:0016605//PML body;GO:0005730//nucleolus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0007596//blood coagulation;GO:0016032//viral process","GO:0042826//histone deacetylase binding;GO:0030674//protein binding, bridging;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0070491//repressing transcription factor binding;GO:0003682//chromatin binding",-
23469,0,1,0,30,106,7,0,0,36,0,7,0,PHF3;PHD finger protein 3,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding,-
23471,0,73,1,10,28,20,0,0,20,0,0,0,TRAM1;translocation associated membrane protein 1,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0016032//viral process;GO:0006412//translation;GO:0006613//cotranslational protein targeting to membrane,GO:0005515//protein binding;GO:0004872//receptor activity,K14010//Protein processing in endoplasmic reticulum
23473,17,0,1,9,43,29,0,0,17,0,0,0,CAPN7;calpain 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0097264//self proteolysis;GO:0010634//positive regulation of epithelial cell migration,GO:0005515//protein binding;GO:0090541//MIT domain binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0004175//endopeptidase activity,-
23474,48,26,0,0,0,0,0,0,32,0,0,0,ETHE1;ethylmalonic encephalopathy 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0000098//sulfur amino acid catabolic process;GO:0006749//glutathione metabolic process;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0044281//small molecule metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0070813//hydrogen sulfide metabolic process",GO:0050313//sulfur dioxygenase activity;GO:0005506//iron ion binding,K01069//Pyruvate metabolism
23475,52,0,0,0,0,0,0,0,27,0,0,0,QPRT;quinolinate phosphoribosyltransferase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0034213//quinolinate catabolic process;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process;GO:0051259//protein oligomerization;GO:0006766//vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0042803//protein homodimerization activity,"K00767//Nicotinate and nicotinamide metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
23476,0,0,0,6,45,23,0,0,27,0,0,0,BRD4;bromodomain containing 4,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0008024//positive transcription elongation factor complex b;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome,"GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:2000002//negative regulation of DNA damage checkpoint;GO:0050727//regulation of inflammatory response;GO:0043388//positive regulation of DNA binding;GO:0001833//inner cell mass cell proliferation;GO:0006351//transcription, DNA-templated;GO:0043983//histone H4-K12 acetylation;GO:0044154//histone H3-K14 acetylation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0016032//viral process;GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1901407//regulation of phosphorylation of RNA polymerase II C-terminal domain;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0006338//chromatin remodeling",GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0005515//protein binding;GO:0002039//p53 binding;GO:0003677//DNA binding,-
23478,119,2,1,43,119,0,16,0,0,0,0,0,SEC11A;SEC11 homolog A (S. cerevisiae),GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane,GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0050796//regulation of insulin secretion;GO:0006465//signal peptide processing;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity,K13280//Protein export
23480,0,0,0,73,88,0,1,0,0,0,0,0,SEC61G;Sec61 gamma subunit,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0071806//protein transmembrane transport",GO:0008565//protein transporter activity;GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity,K07342//Vibrio cholerae infection;Protein export;Phagosome;Protein processing in endoplasmic reticulum
23481,2,18,0,8,13,29,39,0,30,87,0,0,PES1;pescadillo ribosomal biogenesis factor 1,"GO:0000793//condensed chromosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0030687//preribosome, large subunit precursor;GO:0005737//cytoplasm;GO:0070545//PeBoW complex;GO:0005654//nucleoplasm","GO:0007000//nucleolus organization;GO:0042273//ribosomal large subunit biogenesis;GO:0006364//rRNA processing;GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0008283//cell proliferation;GO:0051726//regulation of cell cycle;GO:0033365//protein localization to organelle",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0043021//ribonucleoprotein complex binding,-
23483,43,0,0,8,0,10,0,0,8,0,0,0,"TGDS;TDP-glucose 4,6-dehydratase",-,GO:0009225//nucleotide-sugar metabolic process,"GO:0008460//dTDP-glucose 4,6-dehydratase activity;GO:0050662//coenzyme binding",K01710//Polyketide sugar unit biosynthesis;DNA replication;Metabolic pathways;ABC transporters;Mismatch repair;Biosynthesis of secondary metabolites;Homologous recombination;Streptomycin biosynthesis
23484,0,0,0,0,0,0,30,0,25,0,10,0,LEPROTL1;leptin receptor overlapping transcript-like 1,GO:0016021//integral component of membrane,-,-,-
23491,0,0,0,0,0,6,0,27,33,0,0,0,CES3;carboxylesterase 3,GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
23492,0,25,2,13,13,0,0,1,7,0,10,0,CBX7;chromobox homolog 7,GO:0005737//cytoplasm;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005730//nucleolus;GO:0035102//PRC1 complex;GO:0031519//PcG protein complex,"GO:0016568//chromatin modification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048733//sebaceous gland development;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003727//single-stranded RNA binding;GO:0035064//methylated histone binding;GO:0005515//protein binding,-
23493,0,0,0,0,0,0,0,0,11,0,0,0,HEY2;hes-related family bHLH transcription factor with YRPW motif 2,GO:0017053//transcriptional repressor complex;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0061314//Notch signaling involved in heart development;GO:0003199//endocardial cushion to mesenchymal transition involved in heart valve formation;GO:2001212//regulation of vasculogenesis;GO:0003186//tricuspid valve morphogenesis;GO:0010460//positive regulation of heart rate;GO:0010629//negative regulation of gene expression;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0003215//cardiac right ventricle morphogenesis;GO:0003184//pulmonary valve morphogenesis;GO:0014031//mesenchymal cell development;GO:0060716//labyrinthine layer blood vessel development;GO:0051145//smooth muscle cell differentiation;GO:0097084//vascular smooth muscle cell development;GO:0009948//anterior/posterior axis specification;GO:0003151//outflow tract morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0035912//dorsal aorta morphogenesis;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0061156//pulmonary artery morphogenesis;GO:0065004//protein-DNA complex assembly;GO:0003214//cardiac left ventricle morphogenesis;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0060948//cardiac vascular smooth muscle cell development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0035910//ascending aorta morphogenesis;GO:0060411//cardiac septum morphogenesis;GO:0003150//muscular septum morphogenesis;GO:0001570//vasculogenesis;GO:0060413//atrial septum morphogenesis;GO:0045165//cell fate commitment;GO:2000723//negative regulation of cardiac vascular smooth muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0060347//heart trabecula formation;GO:0036304//umbilical cord morphogenesis;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0060977//coronary vasculature morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0055015//ventricular cardiac muscle cell development;GO:2000820//negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0007219//Notch signaling pathway;GO:0060842//arterial endothelial cell differentiation;GO:0003195//tricuspid valve formation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0045746//negative regulation of Notch signaling pathway;GO:0090102//cochlea development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0000988//protein binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0035939//microsatellite binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding,-
23495,0,0,0,0,0,0,0,0,12,0,0,0,"TNFRSF13B;tumor necrosis factor receptor superfamily, member 13B",GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0030889//negative regulation of B cell proliferation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0001782//B cell homeostasis,GO:0005515//protein binding;GO:0004872//receptor activity,K05150//Cytokine-cytokine receptor interaction;Primary immunodeficiency;Intestinal immune network for IgA production
23498,0,0,0,5,16,0,35,0,33,0,0,0,"HAAO;3-hydroxyanthranilate 3,4-dioxygenase",GO:0031966//mitochondrial membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006569//tryptophan catabolic process;GO:0019805//quinolinate biosynthetic process;GO:0010043//response to zinc ion;GO:0034641//cellular nitrogen compound metabolic process;GO:0046686//response to cadmium ion;GO:0070050//neuron cellular homeostasis;GO:0055114//oxidation-reduction process;GO:0043420//anthranilate metabolic process;GO:0034354//'de novo' NAD biosynthetic process from tryptophan,"GO:0000334//3-hydroxyanthranilate 3,4-dioxygenase activity;GO:0019825//oxygen binding;GO:0008198//ferrous iron binding;GO:0009055//electron carrier activity",K00452//Metabolic pathways;Tryptophan metabolism
23499,193,126,0,34,89,55,51,163,229,1,3,2,MACF1;microtubule-actin crosslinking factor 1,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0032587//ruffle membrane,GO:0051893//regulation of focal adhesion assembly;GO:0042060//wound healing;GO:0032886//regulation of microtubule-based process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043001//Golgi to plasma membrane protein transport;GO:0007050//cell cycle arrest;GO:0006200//ATP catabolic process;GO:0016055//Wnt signaling pathway,GO:0016887//ATPase activity;GO:0051015//actin filament binding;GO:0005509//calcium ion binding;GO:0044822//poly(A) RNA binding;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003779//actin binding,-
2350,12,0,0,0,0,8,21,0,0,0,0,0,FOLR2;folate receptor 2 (fetal),GO:0031362//anchored component of external side of plasma membrane;GO:0016020//membrane;GO:0005576//extracellular region,GO:0015884//folic acid transport,GO:0008517//folic acid transporter activity;GO:0005542//folic acid binding,K13649//Endocytosis
23500,45,0,0,7,0,54,0,0,20,97,25,0,DAAM2;dishevelled associated activator of morphogenesis 2,-,GO:0007368//determination of left/right symmetry;GO:0030036//actin cytoskeleton organization,GO:0017048//Rho GTPase binding;GO:0003779//actin binding,K04512//Wnt signaling pathway
23503,0,16,0,2,7,7,21,68,88,29,34,0,"ZFYVE26;zinc finger, FYVE domain containing 26",GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0030496//midbody,GO:0000724//double-strand break repair via homologous recombination;GO:0008219//cell death;GO:0000910//cytokinesis,GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
23504,31,0,0,0,0,0,50,0,70,2,6,0,RIMBP2;RIMS binding protein 2,GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane,GO:0010923//negative regulation of phosphatase activity,-,K05088//MAPK signaling pathway - fly
23505,10,8,0,12,10,7,0,0,38,349,1,0,TMEM131;transmembrane protein 131,GO:0016021//integral component of membrane,-,-,-
23506,86,0,0,5,132,68,0,0,10,0,0,0,GLTSCR1L;GLTSCR1-like,-,-,-,-
23507,0,0,1,6,5,36,9,0,115,2,11,45,"LRRC8B;leucine rich repeat containing 8 family, member B",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport,GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway
23508,0,1,0,0,0,0,1,3,21,0,15,0,TTC9;tetratricopeptide repeat domain 9,-,-,-,-
23509,0,2,0,15,13,0,11,1,50,0,8,0,POFUT1;protein O-fucosyltransferase 1,GO:0016020//membrane;GO:0005783//endoplasmic reticulum,"GO:0006493//protein O-linked glycosylation;GO:0007399//nervous system development;GO:0006004//fucose metabolic process;GO:0036066//protein O-linked fucosylation;GO:0007507//heart development;GO:0007219//Notch signaling pathway;GO:0001525//angiogenesis;GO:0001756//somitogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0016266//O-glycan processing;GO:0009790//embryo development",GO:0046922//peptide-O-fucosyltransferase activity,K03691//Other types of O-glycan biosynthesis
23510,0,25,0,18,22,0,0,0,3,15,1,0,KCTD2;potassium channel tetramerization domain containing 2,-,GO:0051260//protein homooligomerization,GO:0032403//protein complex binding,K08023//TGF-beta signaling pathway
23511,0,1,46,6,40,17,15,13,90,0,6,0,NUP188;nucleoporin 188kDa,GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0016020//membrane,GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport,-,K14311//RNA transport
23512,156,53,1,9,89,1,29,0,15,0,0,0,SUZ12;SUZ12 polycomb repressive complex 2 subunit,GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0001739//sex chromatin,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0016571//histone methylation;GO:0045596//negative regulation of cell differentiation;GO:0016574//histone ubiquitination;GO:0006351//transcription, DNA-templated",GO:0035064//methylated histone binding;GO:0042054//histone methyltransferase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003723//RNA binding,-
23513,37,0,0,8,1,15,0,0,62,0,28,0,SCRIB;scribbled planar cell polarity protein,GO:0045211//postsynaptic membrane;GO:0042734//presynaptic membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031252//cell leading edge;GO:0005913//cell-cell adherens junction;GO:0030027//lamellipodium;GO:0005911//cell-cell junction;GO:0016323//basolateral plasma membrane;GO:0034750//Scrib-APC-beta-catenin complex;GO:0035748//myelin sheath abaxonal region,GO:0048488//synaptic vesicle endocytosis;GO:0043065//positive regulation of apoptotic process;GO:0071896//protein localization to adherens junction;GO:0001921//positive regulation of receptor recycling;GO:0035089//establishment of apical/basal cell polarity;GO:0016080//synaptic vesicle targeting;GO:0001843//neural tube closure;GO:0060603//mammary gland duct morphogenesis;GO:0032863//activation of Rac GTPase activity;GO:0016032//viral process;GO:0016477//cell migration;GO:0060088//auditory receptor cell stereocilium organization;GO:0043615//astrocyte cell migration;GO:0016337//single organismal cell-cell adhesion;GO:0021747//cochlear nucleus development;GO:0042060//wound healing;GO:0008283//cell proliferation;GO:0008105//asymmetric protein localization;GO:0045930//negative regulation of mitotic cell cycle;GO:0060561//apoptotic process involved in morphogenesis;GO:0050918//positive chemotaxis,GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway
23514,0,2,2,40,64,43,1,0,14,0,13,0,SPIDR;scaffolding protein involved in DNA repair,GO:0000228//nuclear chromosome,GO:0000724//double-strand break repair via homologous recombination;GO:0072711//cellular response to hydroxyurea;GO:0071479//cellular response to ionizing radiation;GO:0006974//cellular response to DNA damage stimulus;GO:0072757//cellular response to camptothecin;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0031334//positive regulation of protein complex assembly;GO:2000781//positive regulation of double-strand break repair;GO:0070202//regulation of establishment of protein localization to chromosome,GO:0005515//protein binding,-
23515,0,0,0,17,61,0,0,0,34,15,12,0,MORC3;MORC family CW-type zinc finger 3,GO:0016605//PML body,GO:0018105//peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0050821//protein stabilization;GO:0048147//negative regulation of fibroblast proliferation;GO:0009791//post-embryonic development;GO:0007569//cell aging;GO:0051457//maintenance of protein location in nucleus,GO:0008270//zinc ion binding,K14000//Protein processing in endoplasmic reticulum
23516,83,0,0,0,0,14,16,0,35,0,10,1,"SLC39A14;solute carrier family 39 (zinc transporter), member 14",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane;GO:0030027//lamellipodium,GO:0006882//cellular zinc ion homeostasis;GO:0071578//zinc ion transmembrane import;GO:0055085//transmembrane transport;GO:0015684//ferrous iron transport;GO:0071577//zinc ion transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity,-
23517,2,443,281,1091,1363,21,21,0,23,0,1044,0,SKIV2L2;superkiller viralicidic activity 2-like 2 (S. cerevisiae),GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0000460//maturation of 5.8S rRNA;GO:0000398//mRNA splicing, via spliceosome",GO:0004386//helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,K12598//RNA degradation
23518,0,0,1,0,66,0,35,0,17,0,0,0,R3HDM1;R3H domain containing 1,-,-,GO:0044822//poly(A) RNA binding,K02360//Dorso-ventral axis formation
23519,0,0,0,0,0,0,0,0,10,0,0,0,"ANP32D;acidic (leucine-rich) nuclear phosphoprotein 32 family, member D",GO:0016363//nuclear matrix,-,-,K11092//Spliceosome
2352,0,0,0,0,0,0,0,0,28,152,0,60,FOLR3;folate receptor 3 (gamma),GO:0019898//extrinsic component of membrane;GO:0005576//extracellular region;GO:0016020//membrane,GO:0015884//folic acid transport,GO:0005542//folic acid binding,K13649//Endocytosis
23520,0,1,0,0,0,0,0,0,0,0,9,0,"ANP32C;acidic (leucine-rich) nuclear phosphoprotein 32 family, member C",-,-,-,-
23521,0,140,32,46,253,0,1,0,24,0,0,0,RPL13A;ribosomal protein L13a,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0015934//large ribosomal subunit;GO:0097452//GAIT complex;GO:0022625//cytosolic large ribosomal subunit,"GO:0016071//mRNA metabolic process;GO:0017148//negative regulation of translation;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0071346//cellular response to interferon-gamma;GO:0016032//viral process;GO:1901194//negative regulation of formation of translation preinitiation complex;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0010467//gene expression;GO:0006412//translation",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02872//Ribosome
23522,0,0,2,10,51,0,92,0,25,0,0,0,KAT6B;K(lysine) acetyltransferase 6B,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000786//nucleosome;GO:0070776//MOZ/MORF histone acetyltransferase complex,"GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0006334//nucleosome assembly",GO:0016407//acetyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0008134//transcription factor binding,-
23523,134,2,1,9,3,14,105,66,11,0,10,0,CABIN1;calcineurin binding protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016235//aggresome;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0006336//DNA replication-independent nucleosome assembly;GO:0007166//cell surface receptor signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0016568//chromatin modification,GO:0004864//protein phosphatase inhibitor activity,-
23524,0,6,95,30,130,0,11,4,21,36,17,0,SRRM2;serine/arginine repetitive matrix 2,GO:0005634//nucleus;GO:0015030//Cajal body;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0016607//nuclear speck,"GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0047485//protein N-terminus binding;GO:0070742//C2H2 zinc finger domain binding,-
23526,0,179,51,256,431,34,41,493,131,378,672,294,HMHA1;histocompatibility (minor) HA-1,GO:0005829//cytosol;GO:0016020//membrane,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0046872//metal ion binding;GO:0005096//GTPase activator activity,K04450//Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction;Influenza A;Alcoholism;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;K02649//Phosphatidylinositol signaling system;Insulin signaling pathway;Prostate cancer;Aldosterone-regulated sodium reabsorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chronic myeloid leukemia;Colorectal cancer;Amoebiasis;Type II diabetes mellitus;Chagas disease (American trypanosomiasis);Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Non-small cell lung cancer;Melanoma;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Hepatitis C;Measles;Chemokine signaling pathway;Pathways in cancer;Pancreatic cancer;Influenza A;Toll-like receptor signaling pathway;Apoptosis;mTOR signaling pathway;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Osteoclast differentiation;Toxoplasmosis;Endometrial cancer;Glioma;Focal adhesion;VEGF signaling pathway
23527,107,24,0,23,34,0,0,0,91,162,0,0,"ACAP2;ArfGAP with coiled-coil, ankyrin repeat and PH domains 2",GO:0016020//membrane;GO:0010008//endosome membrane,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:1990090//cellular response to nerve growth factor stimulus;GO:0036010//protein localization to endosome,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0017137//Rab GTPase binding,K12489//Endocytosis
23528,0,0,0,12,6,3,20,0,0,0,0,0,ZNF281;zinc finger protein 281,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048863//stem cell differentiation;GO:0010172//embryonic body morphogenesis",GO:0044212//transcription regulatory region DNA binding;GO:0003714//transcription corepressor activity;GO:0001047//core promoter binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23529,34,0,0,0,0,3,0,0,20,120,3,0,CLCF1;cardiotrophin-like cytokine factor 1,GO:0097058//CRLF-CLCF1 complex;GO:0070062//extracellular vesicular exosome;GO:0097059//CNTFR-CLCF1 complex;GO:0005576//extracellular region,GO:0007166//cell surface receptor signaling pathway;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0048711//positive regulation of astrocyte differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0002639//positive regulation of immunoglobulin production;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0043524//negative regulation of neuron apoptotic process;GO:0030183//B cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0030890//positive regulation of B cell proliferation;GO:0007259//JAK-STAT cascade,GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0008083//growth factor activity;GO:0005102//receptor binding;GO:0005127//ciliary neurotrophic factor receptor binding,K05421//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
2353,0,0,0,0,0,0,0,0,13,0,0,0,FOS;FBJ murine osteosarcoma viral oncogene homolog,GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0043005//neuron projection;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0051591//response to cAMP;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030431//sleep;GO:0006954//inflammatory response;GO:0009416//response to light stimulus;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0032870//cellular response to hormone stimulus;GO:0032570//response to progesterone;GO:0034097//response to cytokine;GO:0009612//response to mechanical stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0071277//cellular response to calcium ion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0034614//cellular response to reactive oxygen species;GO:0034134//toll-like receptor 2 signaling pathway;GO:0001661//conditioned taste aversion;GO:0045672//positive regulation of osteoclast differentiation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0007568//aging;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006306//DNA methylation;GO:0051412//response to corticosterone;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0031668//cellular response to extracellular stimulus;GO:0035914//skeletal muscle cell differentiation;GO:0045087//innate immune response;GO:0007565//female pregnancy;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0009636//response to toxic substance;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009629//response to gravity;GO:0009409//response to cold;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway",GO:0003690//double-stranded DNA binding;GO:0070412//R-SMAD binding;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0008134//transcription factor binding,K04379//Cholinergic synapse;HTLV-I infection;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;Osteoclast differentiation;Leishmaniasis;Rheumatoid arthritis;Salmonella infection;Pathways in cancer;Dopaminergic synapse;Toll-like receptor signaling pathway;Pertussis;Amphetamine addiction;T cell receptor signaling pathway;MAPK signaling pathway;Herpes simplex infection;Colorectal cancer
23530,0,2,0,24,100,8,21,0,18,257,30,0,NNT;nicotinamide nucleotide transhydrogenase,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respiratory chain,GO:1902600//hydrogen ion transmembrane transport;GO:0055114//oxidation-reduction process;GO:0015992//proton transport;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process,GO:0051287//NAD binding;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0008750//NAD(P)+ transhydrogenase (AB-specific) activity;GO:0050661//NADP binding;GO:0003957//NAD(P)+ transhydrogenase (B-specific) activity,K00323//Metabolic pathways;Nicotinate and nicotinamide metabolism
23531,0,0,0,0,0,11,0,0,54,0,0,0,MMD;monocyte to macrophage differentiation-associated,GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0019835//cytolysis,GO:0004872//receptor activity,-
23532,0,0,0,0,1,0,0,0,22,0,0,0,PRAME;preferentially expressed antigen in melanoma,GO:0005886//plasma membrane;GO:0005634//nucleus,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth",GO:0042974//retinoic acid receptor binding;GO:0005515//protein binding,-
23533,1,0,0,0,0,0,20,79,20,151,0,409,"PIK3R5;phosphoinositide-3-kinase, regulatory subunit 5","GO:0005829//cytosol;GO:0016020//membrane;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0005634//nucleus;GO:0005737//cytoplasm",GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0007596//blood coagulation;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0008219//cell death;GO:0051897//positive regulation of protein kinase B signaling;GO:0044281//small molecule metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0030168//platelet activation,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity,K02649//Phosphatidylinositol signaling system;Insulin signaling pathway;Prostate cancer;Aldosterone-regulated sodium reabsorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chronic myeloid leukemia;Amoebiasis;Colorectal cancer;Type II diabetes mellitus;Chagas disease (American trypanosomiasis);Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Non-small cell lung cancer;Melanoma;Hepatitis C;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Measles;Pathways in cancer;Chemokine signaling pathway;Pancreatic cancer;Influenza A;Toll-like receptor signaling pathway;Apoptosis;mTOR signaling pathway;ErbB signaling pathway;Epstein-Barr virus infection;Renal cell carcinoma;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Osteoclast differentiation;Toxoplasmosis;Endometrial cancer;Glioma;Focal adhesion;VEGF signaling pathway
23534,38,0,19,27,107,0,0,11,22,0,4,1,TNPO3;transportin 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,GO:0035048//splicing factor protein import into nucleus,GO:0005515//protein binding;GO:0004872//receptor activity,-
23536,0,0,1,20,58,27,0,0,20,0,0,0,"ADAT1;adenosine deaminase, tRNA-specific 1",-,GO:0008033//tRNA processing,GO:0046872//metal ion binding;GO:0008251//tRNA-specific adenosine deaminase activity;GO:0003723//RNA binding,-
23539,0,0,41,0,5,0,0,46,26,0,7,0,"SLC16A8;solute carrier family 16 (monocarboxylate transporter), member 8",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0007596//blood coagulation;GO:0006090//pyruvate metabolic process;GO:0055085//transmembrane transport;GO:0044237//cellular metabolic process;GO:0035873//lactate transmembrane transport;GO:0044281//small molecule metabolic process;GO:0050900//leukocyte migration,GO:0015355//secondary active monocarboxylate transmembrane transporter activity;GO:0015293//symporter activity;GO:0015129//lactate transmembrane transporter activity,-
2354,86,0,0,0,0,0,0,0,13,0,0,0,FOSB;FBJ murine osteosarcoma viral oncogene homolog B,GO:0005634//nucleus,GO:0032870//cellular response to hormone stimulus;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0043278//response to morphine;GO:0051591//response to cAMP;GO:0071277//cellular response to calcium ion;GO:0032570//response to progesterone;GO:0006366//transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0051412//response to corticosterone;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0003690//double-stranded DNA binding,K09029//Alcoholism;Osteoclast differentiation;Amphetamine addiction;Cocaine addiction
23541,83,143,2,23,113,18,3,0,35,1,0,0,SEC14L2;SEC14-like 2 (S. cerevisiae),GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045540//regulation of cholesterol biosynthetic process;GO:0006810//transport",GO:0005215//transporter activity;GO:0008431//vitamin E binding;GO:0005543//phospholipid binding,-
23542,107,0,0,0,0,41,14,0,26,0,0,0,MAPK8IP2;mitogen-activated protein kinase 8 interacting protein 2,GO:0097481//neuronal postsynaptic density;GO:0005737//cytoplasm,"GO:0046328//regulation of JNK cascade;GO:0046958//nonassociative learning;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0035176//social behavior;GO:0048813//dendrite morphogenesis;GO:0000165//MAPK cascade;GO:0045860//positive regulation of protein kinase activity;GO:0007172//signal complex assembly;GO:0009967//positive regulation of signal transduction;GO:0001662//behavioral fear response;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0010469//regulation of receptor activity",GO:0019894//kinesin binding;GO:0019901//protein kinase binding;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005078//MAP-kinase scaffold activity;GO:0001540//beta-amyloid binding;GO:0030295//protein kinase activator activity,K04435//MAPK signaling pathway
23543,0,2,3,60,130,0,2,50,23,109,7,0,"RBFOX2;RNA binding protein, fox-1 homolog (C. elegans) 2",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0050885//neuromuscular process controlling balance;GO:0008380//RNA splicing;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0006397//mRNA processing;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0021942//radial glia guided migration of Purkinje cell;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048813//dendrite morphogenesis;GO:0016070//RNA metabolic process;GO:0042127//regulation of cell proliferation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0008134//transcription factor binding;GO:0003729//mRNA binding;GO:0003714//transcription corepressor activity;GO:0003723//RNA binding,-
23544,116,0,0,0,0,7,28,0,46,62,8,0,SEZ6L;seizure related 6 homolog (mouse)-like,GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0005789//endoplasmic reticulum membrane,GO:0008344//adult locomotory behavior;GO:0021680//cerebellar Purkinje cell layer development;GO:0090036//regulation of protein kinase C signaling;GO:0060074//synapse maturation,-,-
23545,90,0,52,0,24,29,26,0,36,131,1,1,"ATP6V0A2;ATPase, H+ transporting, lysosomal V0 subunit a2","GO:0001669//acrosomal vesicle;GO:0005765//lysosomal membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005737//cytoplasm;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane",GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0006955//immune response,GO:0005515//protein binding;GO:0015078//hydrogen ion transmembrane transporter activity,K02154//Oxidative phosphorylation;Metabolic pathways;Epithelial cell signaling in Helicobacter pylori infection;Lysosome;Vibrio cholerae infection;Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Tuberculosis;Synaptic vesicle cycle
23546,0,0,0,0,0,0,0,0,0,0,3,0,SYNGR4;synaptogyrin 4,GO:0016021//integral component of membrane,-,-,K04403//Osteoclast differentiation;Leishmaniasis;Toxoplasmosis;MAPK signaling pathway;Herpes simplex infection;Epstein-Barr virus infection;NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway
23547,125,0,0,0,0,12,0,0,25,0,0,0,"LILRA4;leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4",GO:0016021//integral component of membrane,GO:0002376//immune system process,GO:0005515//protein binding,K06512//Osteoclast differentiation;B cell receptor signaling pathway
23548,0,0,1,14,11,26,3,0,0,0,3,0,TTC33;tetratricopeptide repeat domain 33,-,-,-,K07198//Adipocytokine signaling pathway;Regulation of autophagy;Hypertrophic cardiomyopathy (HCM);mTOR signaling pathway;Insulin signaling pathway;K09553//Prion diseases
23549,154,29,0,0,1,0,0,66,22,0,11,0,DNPEP;aspartyl aminopeptidase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0072562//blood microparticle,GO:0006508//proteolysis;GO:0006518//peptide metabolic process,GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
2355,0,44,0,9,8,0,0,0,7,1,12,0,FOSL2;FOS-like antigen 2,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0051591//response to cAMP;GO:0043278//response to morphine;GO:0008219//cell death;GO:0042493//response to drug;GO:0032870//cellular response to hormone stimulus;GO:0007565//female pregnancy;GO:0032570//response to progesterone;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0051412//response to corticosterone;GO:0006366//transcription from RNA polymerase II promoter;GO:0048146//positive regulation of fibroblast proliferation,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003690//double-stranded DNA binding,K09030//Osteoclast differentiation
23550,0,38,22,11,37,0,48,3,52,0,2,0,PSD4;pleckstrin and Sec7 domain containing 4,GO:0005802//trans-Golgi network;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0043547//positive regulation of GTPase activity;GO:0016192//vesicle-mediated transport;GO:0030182//neuron differentiation;GO:0032012//regulation of ARF protein signal transduction,GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005543//phospholipid binding,K12494//Endocytosis
23551,0,0,0,0,0,18,0,0,28,0,0,0,"RASD2;RASD family, member 2",GO:0005886//plasma membrane,"GO:0006184//GTP catabolic process;GO:0033235//positive regulation of protein sumoylation;GO:0031397//negative regulation of protein ubiquitination;GO:0043949//regulation of cAMP-mediated signaling;GO:0007264//small GTPase mediated signal transduction;GO:0007626//locomotory behavior;GO:0051897//positive regulation of protein kinase B signaling;GO:0001963//synaptic transmission, dopaminergic",GO:0031681//G-protein beta-subunit binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0031624//ubiquitin conjugating enzyme binding,-
23552,0,0,0,0,0,1,0,0,46,0,0,0,CDK20;cyclin-dependent kinase 20,GO:0005929//cilium;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051301//cell division;GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0007049//cell cycle;GO:0051726//regulation of cell cycle,GO:0005515//protein binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
23553,0,0,0,0,0,21,11,0,14,0,0,0,HYAL4;hyaluronoglucosaminidase 4,GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0006027//glycosaminoglycan catabolic process,GO:0004415//hyalurononglucosaminidase activity,"K01197//Arginine and proline metabolism;Lysosome;Glycosaminoglycan degradation;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
23554,0,0,25,0,0,11,0,0,21,0,0,0,TSPAN12;tetraspanin 12,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0010842//retina layer formation;GO:0007166//cell surface receptor signaling pathway;GO:0045765//regulation of angiogenesis;GO:0001525//angiogenesis,GO:0042813//Wnt-activated receptor activity,K06460//Hematopoietic cell lineage
23555,0,0,0,0,0,0,0,0,13,0,0,0,TSPAN15;tetraspanin 15,GO:0097197//tetraspanin-enriched microdomain;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0051604//protein maturation;GO:0090002//establishment of protein localization to plasma membrane;GO:0008593//regulation of Notch signaling pathway,GO:0019899//enzyme binding,K13857//Bile secretion
23556,59,0,0,0,2,8,2,0,72,0,2,0,"PIGN;phosphatidylinositol glycan anchor biosynthesis, class N",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane,GO:0016740//transferase activity,K05285//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
23557,0,0,0,9,0,0,0,0,2,0,0,0,SNAPIN;SNAP-associated protein,GO:0030659//cytoplasmic vesicle membrane;GO:0008021//synaptic vesicle;GO:0000139//Golgi membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005794//Golgi apparatus;GO:0030672//synaptic vesicle membrane;GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex;GO:0030141//secretory granule;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm,GO:0006886//intracellular protein transport;GO:0043393//regulation of protein binding;GO:0031629//synaptic vesicle fusion to presynaptic membrane;GO:0016032//viral process;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0008333//endosome to lysosome transport;GO:0008089//anterograde axon cargo transport;GO:1902824//positive regulation of late endosome to lysosome transport;GO:0031175//neuron projection development;GO:0010977//negative regulation of neuron projection development;GO:0048489//synaptic vesicle transport;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0072553//terminal button organization;GO:0016188//synaptic vesicle maturation,GO:0000149//SNARE binding;GO:0005515//protein binding,-
23558,0,13,1,12,117,25,0,17,21,0,3,0,WBP2;WW domain binding protein 2,GO:0000790//nuclear chromatin,"GO:0045815//positive regulation of gene expression, epigenetic;GO:0045184//establishment of protein localization;GO:0071442//positive regulation of histone H3-K14 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071391//cellular response to estrogen stimulus",GO:0031490//chromatin DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding,-
23559,0,0,0,0,0,0,0,0,0,0,13,0,WBP1;WW domain binding protein 1,-,-,GO:0005515//protein binding;GO:0050699//WW domain binding,-
2356,0,0,0,0,2,1,1,0,0,0,0,222,FPGS;folylpolyglutamate synthase,GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0001889//liver development;GO:0046655//folic acid metabolic process;GO:0046901//tetrahydrofolylpolyglutamate biosynthetic process;GO:0031100//organ regeneration;GO:0006730//one-carbon metabolic process;GO:0007420//brain development;GO:0006766//vitamin metabolic process;GO:0006139//nucleobase-containing compound metabolic process,GO:0005524//ATP binding;GO:0004326//tetrahydrofolylpolyglutamate synthase activity,K01930//Folate biosynthesis;Metabolic pathways
23560,0,0,0,8,15,0,0,0,45,0,22,0,GTPBP4;GTP binding protein 4,GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0031965//nuclear membrane,GO:0008156//negative regulation of DNA replication;GO:0022408//negative regulation of cell-cell adhesion;GO:0001649//osteoblast differentiation;GO:0030336//negative regulation of cell migration;GO:0050821//protein stabilization;GO:0042254//ribosome biogenesis;GO:0031397//negative regulation of protein ubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006184//GTP catabolic process;GO:0033342//negative regulation of collagen binding,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K06943//Ribosome biogenesis in eukaryotes
23562,151,0,0,0,0,0,0,0,43,0,4,0,CLDN14;claudin 14,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0070830//tight junction assembly;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045216//cell-cell junction organization;GO:0034329//cell junction assembly;GO:0006461//protein complex assembly,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Cell adhesion molecules (CAMs);Tight junction
23563,0,0,0,0,0,0,0,29,19,0,0,0,CHST5;carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5,GO:0031228//intrinsic component of Golgi membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006477//protein sulfation;GO:0044281//small molecule metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0006790//sulfur compound metabolic process,GO:0008146//sulfotransferase activity;GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity,K09671//Glycosaminoglycan biosynthesis - keratan sulfate
23566,0,15,0,17,47,12,0,0,0,0,2,0,LPAR3;lysophosphatidic acid receptor 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030424//axon,"GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048672//positive regulation of collateral sprouting;GO:0032060//bleb assembly;GO:0007268//synaptic transmission;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0000187//activation of MAPK activity;GO:0051928//positive regulation of calcium ion transport",GO:0005543//phospholipid binding;GO:0070915//lysophosphatidic acid receptor activity;GO:0008289//lipid binding;GO:0001965//G-protein alpha-subunit binding;GO:0004930//G-protein coupled receptor activity,K04294//Neuroactive ligand-receptor interaction
23567,0,0,0,0,0,0,17,0,0,166,10,0,ZNF346;zinc finger protein 346,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043065//positive regulation of apoptotic process,GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003725//double-stranded RNA binding;GO:0008270//zinc ion binding,K10137//p53 signaling pathway
23568,0,25,0,14,37,13,2,0,22,0,0,0,ARL2BP;ADP-ribosylation factor-like 2 binding protein,GO:0005819//spindle;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005929//cilium;GO:0030496//midbody;GO:0005758//mitochondrial intermembrane space,GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0051457//maintenance of protein location in nucleus;GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:2001141//regulation of RNA biosynthetic process,GO:0005515//protein binding;GO:0005083//small GTPase regulator activity;GO:0003713//transcription coactivator activity,-
23569,0,0,0,0,0,12,0,31,18,67,0,0,"PADI4;peptidyl arginine deiminase, type IV",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045087//innate immune response;GO:0006464//cellular protein modification process;GO:0006334//nucleosome assembly;GO:0018101//protein citrullination;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0036413//histone H3-R26 citrullination;GO:0019827//stem cell maintenance",GO:0016990//arginine deiminase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0004668//protein-arginine deiminase activity,-
2357,0,0,0,0,0,0,26,0,10,0,0,0,FPR1;formyl peptide receptor 1,GO:0005886//plasma membrane;GO:0005768//endosome;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007263//nitric oxide mediated signal transduction;GO:0006928//cellular component movement;GO:0000187//activation of MAPK activity;GO:0006935//chemotaxis;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0004872//receptor activity;GO:0050786//RAGE receptor binding;GO:0005515//protein binding;GO:0004982//N-formyl peptide receptor activity,K04172//Neuroactive ligand-receptor interaction;Staphylococcus aureus infection
23576,0,35,1,180,246,12,0,0,10,104,0,0,DDAH1;dimethylarginine dimethylaminohydrolase 1,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0003073//regulation of systemic arterial blood pressure;GO:0006527//arginine catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0000052//citrulline metabolic process,GO:0046872//metal ion binding;GO:0016597//amino acid binding;GO:0003824//catalytic activity;GO:0016403//dimethylargininase activity,-
2358,0,0,0,0,0,0,0,0,16,0,0,0,FPR2;formyl peptide receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006935//chemotaxis;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0006928//cellular component movement;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004982//N-formyl peptide receptor activity,K04173//Neuroactive ligand-receptor interaction;Staphylococcus aureus infection
23580,0,46,0,43,6,0,20,0,29,0,0,0,CDC42EP4;CDC42 effector protein (Rho GTPase binding) 4,GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton,GO:0008360//regulation of cell shape;GO:0031274//positive regulation of pseudopodium assembly;GO:0007266//Rho protein signal transduction,GO:0044822//poly(A) RNA binding;GO:0017049//GTP-Rho binding,-
23581,0,24,0,0,0,26,0,0,4,0,0,0,"CASP14;caspase 14, apoptosis-related cysteine peptidase",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,GO:0031424//keratinization;GO:0006508//proteolysis;GO:0070268//cornification;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008544//epidermis development;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand,GO:0004197//cysteine-type endopeptidase activity,-
23582,62,47,1,5,5,0,52,0,27,0,1,0,CCNDBP1;cyclin D-type binding-protein 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051726//regulation of cell cycle;GO:0007049//cell cycle,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
23583,0,22,0,0,0,0,14,1,13,0,1,0,SMUG1;single-strand-selective monofunctional uracil-DNA glycosylase 1,GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0006281//DNA repair;GO:0045008//depyrimidination;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006284//base-excision repair",GO:0019104//DNA N-glycosylase activity;GO:0000703//oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity;GO:0005515//protein binding;GO:0017065//single-strand selective uracil DNA N-glycosylase activity;GO:0004844//uracil DNA N-glycosylase activity;GO:0003677//DNA binding,K10800//Base excision repair
23584,0,0,19,0,0,0,0,49,32,0,0,0,VSIG2;V-set and immunoglobulin domain containing 2,GO:0005887//integral component of plasma membrane;GO:0016020//membrane,-,-,K06788//Viral myocarditis
23585,0,0,0,6,1,0,2,91,1,0,0,0,TMEM50A;transmembrane protein 50A,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,-,-
23586,0,43,0,10,42,0,0,0,28,0,0,0,DDX58;DEAD (Asp-Glu-Ala-Asp) box polypeptide 58,GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005923//tight junction;GO:0005737//cytoplasm,GO:0045087//innate immune response;GO:0032727//positive regulation of interferon-alpha production;GO:0032728//positive regulation of interferon-beta production;GO:0034344//regulation of type III interferon production;GO:0032480//negative regulation of type I interferon production;GO:0009597//detection of virus;GO:0043330//response to exogenous dsRNA;GO:0008152//metabolic process;GO:0009615//response to virus;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0030334//regulation of cell migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002230//positive regulation of defense response to virus by host;GO:0039529//RIG-I signaling pathway;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus,GO:0005524//ATP binding;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0003727//single-stranded RNA binding;GO:0042802//identical protein binding;GO:0003690//double-stranded DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,K12646//Herpes simplex infection;Hepatitis C;Cytosolic DNA-sensing pathway;Measles;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;NF-kappa B signaling pathway;Influenza A
23587,0,29,0,9,14,0,0,0,0,0,5,0,ELP5;elongator acetyltransferase complex subunit 5,GO:0033588//Elongator holoenzyme complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0030335//positive regulation of cell migration;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,-
23588,0,0,108,35,15,0,0,62,14,36,16,0,KLHDC2;kelch domain containing 2,GO:0005634//nucleus,-,-,K14966//Herpes simplex infection
23589,0,86,76,26,38,14,26,368,17,0,116,1,"CARHSP1;calcium regulated heat stable protein 1, 24kDa",GO:0043186//P granule;GO:0000932//cytoplasmic mRNA processing body;GO:0000177//cytoplasmic exosome (RNase complex);GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0043488//regulation of mRNA stability",GO:0003677//DNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0019902//phosphatase binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
2359,106,0,0,0,0,0,0,136,8,0,0,0,FPR3;formyl peptide receptor 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006928//cellular component movement,GO:0004982//N-formyl peptide receptor activity,K04173//Staphylococcus aureus infection;Neuroactive ligand-receptor interaction
23590,0,0,0,12,1,0,0,0,2,0,7,0,"PDSS1;prenyl (decaprenyl) diphosphate synthase, subunit 1",GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0008299//isoprenoid biosynthetic process;GO:0051290//protein heterotetramerization,GO:0000010//trans-hexaprenyltranstransferase activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding,K12504//Terpenoid backbone biosynthesis
23592,0,0,0,0,5,0,0,0,64,10,0,0,LEMD3;LEM domain containing 3,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005637//nuclear inner membrane;GO:0005639//integral component of nuclear inner membrane,GO:0035914//skeletal muscle cell differentiation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0051726//regulation of cell cycle;GO:0032926//negative regulation of activin receptor signaling pathway,GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
23593,0,30,0,88,129,0,0,1,0,0,1,626,HEBP2;heme binding protein 2,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0010940//positive regulation of necrotic cell death;GO:1901031//regulation of response to reactive oxygen species;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0035794//positive regulation of mitochondrial membrane permeability,GO:0005515//protein binding,-
23594,0,0,0,0,0,0,0,0,17,0,6,0,"ORC6;origin recognition complex, subunit 6",GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0016020//membrane,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006261//DNA-dependent DNA replication,GO:0005515//protein binding;GO:0003677//DNA binding,K02608//Meiosis - yeast;Cell cycle;Cell cycle - yeast
23595,0,0,0,3,14,12,0,0,27,0,10,0,"ORC3;origin recognition complex, subunit 3",GO:0005664//nuclear origin of replication recognition complex;GO:0005654//nucleoplasm,GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0061351//neural precursor cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle,GO:0005515//protein binding;GO:0003688//DNA replication origin binding,K02605//Meiosis - yeast;Cell cycle;Cell cycle - yeast
23596,0,0,0,0,0,0,0,0,24,0,0,0,OPN3;opsin 3,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane,GO:0009584//detection of visible light;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0042752//regulation of circadian rhythm;GO:0018298//protein-chromophore linkage,GO:0009881//photoreceptor activity;GO:0008020//G-protein coupled photoreceptor activity;GO:0004930//G-protein coupled receptor activity,-
23597,0,0,0,0,29,22,0,0,30,0,0,0,ACOT9;acyl-CoA thioesterase 9,GO:0005739//mitochondrion,GO:0006637//acyl-CoA metabolic process,GO:0052689//carboxylic ester hydrolase activity;GO:0003986//acetyl-CoA hydrolase activity,-
23598,1,13,0,22,12,21,13,0,2,0,0,0,PATZ1;POZ (BTB) and AT hook containing zinc finger 1,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0008584//male gonad development",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
23600,0,0,0,0,0,0,0,0,3,0,0,0,AMACR;alpha-methylacyl-CoA racemase,GO:0005737//cytoplasm;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion,GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0044255//cellular lipid metabolic process;GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0008111//alpha-methylacyl-CoA racemase activity;GO:0005102//receptor binding,K01796//Peroxisome;Primary bile acid biosynthesis;Metabolic pathways
23601,0,0,0,0,0,30,0,0,0,0,0,0,"CLEC5A;C-type lectin domain family 5, member A",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface,GO:0007165//signal transduction;GO:0016032//viral process;GO:0045087//innate immune response;GO:0002076//osteoblast development;GO:0009615//response to virus;GO:0043066//negative regulation of apoptotic process;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0050715//positive regulation of cytokine secretion;GO:0006968//cellular defense response,GO:0030246//carbohydrate binding;GO:0001618//virus receptor activity,-
23603,0,0,0,22,46,11,1,0,0,0,0,0,"CORO1C;coronin, actin binding protein, 1C",GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0007165//signal transduction;GO:0030036//actin cytoskeleton organization;GO:0006909//phagocytosis,GO:0051015//actin filament binding,-
23604,0,0,0,0,4,0,1,69,0,0,0,0,DAPK2;death-associated protein kinase 2,GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0034423//autophagic vacuole lumen,GO:0043276//anoikis;GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0010506//regulation of autophagy;GO:0046777//protein autophosphorylation;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:0042981//regulation of apoptotic process,GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity,K08803//Pathways in cancer;Bladder cancer
23607,27,155,2,127,496,33,53,1,16,0,11,0,CD2AP;CD2-associated protein,GO:0031941//filamentous actin;GO:0030139//endocytic vesicle;GO:0015629//actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,"GO:0048259//regulation of receptor-mediated endocytosis;GO:0016337//single organismal cell-cell adhesion;GO:1900182//positive regulation of protein localization to nucleus;GO:0016050//vesicle organization;GO:0006461//protein complex assembly;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0007165//signal transduction;GO:0006930//substrate-dependent cell migration, cell extension;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:2000249//regulation of actin cytoskeleton reorganization",GO:0045296//cadherin binding;GO:0017124//SH3 domain binding;GO:0008013//beta-catenin binding;GO:0032403//protein complex binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0008022//protein C-terminus binding,K13738//Bacterial invasion of epithelial cells
23608,145,123,2,61,100,1,0,7,41,0,0,0,MKRN1;makorin ring finger protein 1,-,GO:0000209//protein polyubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0003682//chromatin binding,-
23609,0,92,17,83,153,0,0,0,52,0,65,0,MKRN2;makorin ring finger protein 2,GO:0005622//intracellular,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0016874//ligase activity,-
23612,0,1,0,0,0,0,0,60,0,0,0,0,"PHLDA3;pleckstrin homology-like domain, family A, member 3",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0009653//anatomical structure morphogenesis;GO:0051898//negative regulation of protein kinase B signaling;GO:0043065//positive regulation of apoptotic process,"GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",K03914//Endocytosis;Regulation of actin cytoskeleton;Calcium signaling pathway;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
23613,68,0,0,9,44,0,0,41,68,0,0,0,"ZMYND8;zinc finger, MYND-type containing 8",GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0070491//repressing transcription factor binding,K11424//Transcriptional misregulation in cancer;Lysine degradation
23614,0,0,0,0,0,0,0,0,8,0,0,0,PPY2;pancreatic polypeptide 2,-,-,-,-
23615,79,0,0,7,6,0,0,0,14,0,0,0,"PYY2;peptide YY, 2 (pseudogene)",GO:0005576//extracellular region,-,-,-
23616,65,0,0,0,0,14,48,0,33,0,25,0,SH3BP1;SH3-domain binding protein 1,GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0007165//signal transduction,GO:0005096//GTPase activator activity;GO:0017124//SH3 domain binding,K08878//Pathways in cancer;Chronic myeloid leukemia;K04450//MAPK signaling pathway;Amphetamine addiction;Epstein-Barr virus infection;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Influenza A;Alcoholism
23617,0,0,106,0,62,28,20,120,21,0,10,0,TSSK2;testis-specific serine kinase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0001669//acrosomal vesicle,GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0046777//protein autophosphorylation;GO:0007286//spermatid development,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
23619,0,0,0,0,0,14,8,0,10,0,0,0,"ZIM2;zinc finger, imprinted 2",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
23620,0,0,0,0,0,0,1,0,10,0,0,0,NTSR2;neurotensin receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0042391//regulation of membrane potential;GO:0007218//neuropeptide signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007600//sensory perception;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0016492//G-protein coupled neurotensin receptor activity;GO:0004930//G-protein coupled receptor activity,K04212//Neuroactive ligand-receptor interaction
23621,0,429,245,540,1089,36,44,188,24,0,600,551,BACE1;beta-site APP-cleaving enzyme 1,GO:0030659//cytoplasmic vesicle membrane;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network;GO:0005771//multivesicular body;GO:0030424//axon;GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis;GO:0050435//beta-amyloid metabolic process;GO:0006509//membrane protein ectodomain proteolysis,GO:0019899//enzyme binding;GO:0001540//beta-amyloid binding;GO:0004190//aspartic-type endopeptidase activity;GO:0005515//protein binding;GO:0008798//beta-aspartyl-peptidase activity,K04521//Alzheimer's disease
23623,0,0,0,7,47,0,11,58,14,0,0,0,RUSC1;RUN and SH3 domain containing 1,GO:0005874//microtubule;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0031410//cytoplasmic vesicle;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0005769//early endosome,GO:0009967//positive regulation of signal transduction;GO:0000209//protein polyubiquitination,GO:0005070//SH3/SH2 adaptor activity;GO:0003779//actin binding;GO:0005515//protein binding,-
23624,0,0,0,0,0,0,17,0,14,0,0,0,"CBLC;Cbl proto-oncogene C, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0007166//cell surface receptor signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005154//epidermal growth factor receptor binding;GO:0001784//phosphotyrosine binding;GO:0017124//SH3 domain binding;GO:0004871//signal transducer activity;GO:0016874//ligase activity,K04707//ErbB signaling pathway;Measles;T cell receptor signaling pathway;Chronic myeloid leukemia;Ubiquitin mediated proteolysis;Pathways in cancer;Endocytosis;Bacterial invasion of epithelial cells;Insulin signaling pathway;Jak-STAT signaling pathway
23625,0,0,0,0,3,0,0,0,0,0,4,0,"FAM89B;family with sequence similarity 89, member B",GO:0009986//cell surface;GO:0005737//cytoplasm,GO:0060392//negative regulation of SMAD protein import into nucleus;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0001222//transcription corepressor binding,K03358//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis
23626,0,0,0,0,0,0,20,0,23,0,0,0,SPO11;SPO11 meiotic protein covalently bound to DSB,"GO:0005634//nucleus;GO:0000781//chromosome, telomeric region","GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0034502//protein localization to chromosome;GO:0007129//synapsis;GO:0000737//DNA catabolic process, endonucleolytic;GO:0001541//ovarian follicle development;GO:0007141//male meiosis I;GO:0007286//spermatid development;GO:0007292//female gamete generation",GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0003677//DNA binding,K10878//Meiosis - yeast
23627,0,0,0,0,0,9,0,0,5,0,0,253,PRND;prion protein 2 (dublet),GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0051260//protein homooligomerization,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
23629,0,0,0,0,0,0,0,0,5,0,0,0,BRD7P3;bromodomain containing 7 pseudogene 3,-,-,-,-
23630,0,0,0,0,0,0,0,32,0,26,0,0,KCNE1L;KCNE1-like,GO:0008076//voltage-gated potassium channel complex,GO:0060306//regulation of membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0086014//atrial cardiac muscle cell action potential;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:1901379//regulation of potassium ion transmembrane transport;GO:0008016//regulation of heart contraction;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0071435//potassium ion export;GO:0086005//ventricular cardiac muscle cell action potential;GO:2001257//regulation of cation channel activity;GO:0060048//cardiac muscle contraction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086013//membrane repolarization during cardiac muscle cell action potential,GO:0015459//potassium channel regulator activity;GO:0044325//ion channel binding;GO:0005249//voltage-gated potassium channel activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization,-
23632,0,29,0,8,2,24,15,196,20,0,0,1,CA14;carbonic anhydrase XIV,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport,GO:0004089//carbonate dehydratase activity;GO:0046872//metal ion binding,K01672//Collecting duct acid secretion;Pancreatic secretion;Nitrogen metabolism;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
23633,76,14,0,14,103,47,13,58,36,0,7,539,KPNA6;karyopherin alpha 6 (importin alpha 7),GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060135//maternal process involved in female pregnancy;GO:0006607//NLS-bearing protein import into nucleus,GO:0008565//protein transporter activity,K15042//Influenza A
23635,0,0,0,0,40,3,15,0,0,0,29,0,SSBP2;single-stranded DNA binding protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003697//single-stranded DNA binding,-
23636,0,12,0,0,0,23,0,1,0,0,0,0,NUP62;nucleoporin 62kDa,GO:0030529//ribonucleoprotein complex;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0046930//pore complex;GO:0000922//spindle pole;GO:0005643//nuclear pore;GO:0005635//nuclear envelope,"GO:0009966//regulation of signal transduction;GO:0007569//cell aging;GO:0043407//negative regulation of MAP kinase activity;GO:0007166//cell surface receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0006913//nucleocytoplasmic transport;GO:0010827//regulation of glucose transport;GO:0009755//hormone-mediated signaling pathway;GO:0046580//negative regulation of Ras protein signal transduction;GO:0015758//glucose transport;GO:0006351//transcription, DNA-templated;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0055085//transmembrane transport;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0015031//protein transport;GO:0008219//cell death;GO:0046578//regulation of Ras protein signal transduction;GO:0043069//negative regulation of programmed cell death;GO:0051028//mRNA transport;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044281//small molecule metabolic process",GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding;GO:0017056//structural constituent of nuclear pore;GO:0043130//ubiquitin binding;GO:0030159//receptor signaling complex scaffold activity;GO:0042169//SH2 domain binding;GO:0051425//PTB domain binding;GO:0046966//thyroid hormone receptor binding;GO:0003682//chromatin binding,K14306//RNA transport
23637,3,164,1,27,284,18,0,0,32,0,1,0,RABGAP1;RAB GTPase activating protein 1,GO:0005813//centrosome;GO:0005875//microtubule associated complex;GO:0005829//cytosol,GO:0007049//cell cycle;GO:0032851//positive regulation of Rab GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0033124//regulation of GTP catabolic process;GO:1902017//regulation of cilium assembly,GO:0005096//GTPase activator activity;GO:0015631//tubulin binding;GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0003677//DNA binding,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
23639,0,0,0,0,0,9,0,0,14,0,0,0,LRRC6;leucine rich repeat containing 6,GO:0005737//cytoplasm;GO:0005929//cilium,GO:0044458//motile cilium assembly;GO:0030317//sperm motility;GO:0003341//cilium movement;GO:0008584//male gonad development;GO:0036159//inner dynein arm assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0061458//reproductive system development;GO:0036158//outer dynein arm assembly,GO:0005515//protein binding,K11092//Spliceosome
23640,146,0,0,0,1,30,0,0,0,0,2,0,"HSPBP1;HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1",-,GO:0031398//positive regulation of protein ubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006457//protein folding;GO:0043086//negative regulation of catalytic activity,GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding,K09562//Protein processing in endoplasmic reticulum
23641,0,0,0,0,8,34,0,0,18,0,9,0,"LDOC1;leucine zipper, down-regulated in cancer 1",GO:0005634//nucleus,GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding,-
23642,0,0,0,12,13,7,0,0,0,0,0,0,SNHG1;small nucleolar RNA host gene 1 (non-protein coding),-,-,-,-
23643,0,0,0,0,0,0,14,0,17,0,0,0,LY96;lymphocyte antigen 96,GO:0005615//extracellular space;GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0046696//lipopolysaccharide receptor complex,GO:0006954//inflammatory response;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0006968//cellular defense response;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032497//detection of lipopolysaccharide;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0002224//toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway,GO:0001875//lipopolysaccharide receptor activity;GO:0005515//protein binding;GO:0015026//coreceptor activity,K05400//NF-kappa B signaling pathway;Toxoplasmosis;Toll-like receptor signaling pathway;Pertussis;Pathogenic Escherichia coli infection
23644,0,0,0,7,25,0,14,0,36,0,0,0,EDC4;enhancer of mRNA decapping 4,GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0016020//membrane;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0005515//protein binding,K12616//RNA degradation
23645,0,0,0,0,4,0,1,0,15,0,0,174,"PPP1R15A;protein phosphatase 1, regulatory subunit 15A",GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process;GO:0006417//regulation of translation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007050//cell cycle arrest;GO:0007179//transforming growth factor beta receptor signaling pathway,GO:0019901//protein kinase binding;GO:0005515//protein binding,K14019//Protein processing in endoplasmic reticulum
23646,0,0,1,0,6,32,0,0,14,0,18,0,"PLD3;phospholipase D family, member 3",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane,GO:0006655//phosphatidylglycerol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0005515//protein binding;GO:0004630//phospholipase D activity;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity,-
23647,0,43,0,3,54,0,16,98,28,0,0,0,ARFIP2;ADP-ribosylation factor interacting protein 2,GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005886//plasma membrane,GO:0030032//lamellipodium assembly;GO:0031529//ruffle organization;GO:0006928//cellular component movement;GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0048365//Rac GTPase binding;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
23648,170,17,2,20,42,15,22,41,29,0,0,0,SSBP3;single stranded DNA binding protein 3,GO:0005634//nucleus;GO:0043234//protein complex,"GO:0006351//transcription, DNA-templated;GO:0002244//hematopoietic progenitor cell differentiation;GO:0060323//head morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021547//midbrain-hindbrain boundary initiation;GO:2000744//positive regulation of anterior head development;GO:0008284//positive regulation of cell proliferation;GO:0021501//prechordal plate formation;GO:0006461//protein complex assembly",GO:0003697//single-stranded DNA binding,-
23649,0,0,0,0,9,14,0,0,18,103,1,0,"POLA2;polymerase (DNA directed), alpha 2, accessory subunit",GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005658//alpha DNA polymerase:primase complex,"GO:0000082//G1/S transition of mitotic cell cycle;GO:0000060//protein import into nucleus, translocation;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0000723//telomere maintenance;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000722//telomere maintenance via recombination",GO:0046982//protein heterodimerization activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0003677//DNA binding,K02321//DNA replication;Metabolic pathways;Pyrimidine metabolism;Purine metabolism
23650,89,0,0,0,0,0,0,44,26,0,10,0,TRIM29;tripartite motif containing 29,GO:0005737//cytoplasm,GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1900181//negative regulation of protein localization to nucleus,GO:0008270//zinc ion binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23654,0,1,0,0,0,19,0,55,36,0,4,0,PLXNB2;plexin B2,GO:0005887//integral component of plasma membrane;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,GO:0071526//semaphorin-plexin signaling pathway;GO:0008360//regulation of cell shape;GO:0001932//regulation of protein phosphorylation;GO:0007420//brain development;GO:0032319//regulation of Rho GTPase activity;GO:0001843//neural tube closure;GO:0043547//positive regulation of GTPase activity;GO:0007405//neuroblast proliferation;GO:0050772//positive regulation of axonogenesis;GO:2001222//regulation of neuron migration,GO:0017154//semaphorin receptor activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding,K06821//Axon guidance
23657,320,0,0,0,0,0,0,4,22,144,0,0,"SLC7A11;solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11",GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0005856//cytoskeleton,GO:0006979//response to oxidative stress;GO:0070527//platelet aggregation;GO:0070306//lens fiber cell differentiation;GO:0055085//transmembrane transport;GO:0007420//brain development;GO:0006811//ion transport;GO:0007596//blood coagulation;GO:0009636//response to toxic substance;GO:0050900//leukocyte migration;GO:0015813//L-glutamate transport;GO:0035094//response to nicotine;GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport,GO:0015327//cystine:glutamate antiporter activity;GO:0005515//protein binding,-
23658,0,3,0,12,23,0,30,0,6,0,3,0,"LSM5;LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005829//cytosol;GO:0005681//spliceosomal complex;GO:0005634//nucleus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006397//mRNA processing;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0003723//RNA binding;GO:0005515//protein binding,K12624//RNA degradation;Spliceosome
23659,0,0,45,0,0,0,0,3,76,0,0,0,"PLA2G15;phospholipase A2, group XV",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005764//lysosome,GO:0006672//ceramide metabolic process;GO:0009062//fatty acid catabolic process;GO:0046470//phosphatidylcholine metabolic process,GO:0004622//lysophospholipase activity;GO:0005543//phospholipid binding;GO:0047499//calcium-independent phospholipase A2 activity;GO:0008374//O-acyltransferase activity,K06129//Glycerophospholipid metabolism;Lysosome
23660,0,0,1,0,26,19,0,0,16,0,0,0,ZKSCAN5;zinc finger with KRAB and SCAN domains 5,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23670,116,0,0,4,0,1,26,0,73,0,0,0,TMEM2;transmembrane protein 2,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007275//multicellular organismal development,-,K09666//Other types of O-glycan biosynthesis
23671,0,0,0,53,31,55,0,0,2,0,0,0,TMEFF2;transmembrane protein with EGF-like and two follistatin-like domains 2,GO:0005576//extracellular region;GO:0016021//integral component of membrane,-,-,K06254//ECM-receptor interaction
23673,0,31,0,33,242,0,4,0,41,0,0,0,STX12;syntaxin 12,GO:0010008//endosome membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0045335//phagocytic vesicle;GO:0031201//SNARE complex;GO:0070062//extracellular vesicular exosome;GO:0031083//BLOC-1 complex,GO:0006886//intracellular protein transport;GO:0033344//cholesterol efflux;GO:0016079//synaptic vesicle exocytosis;GO:0050821//protein stabilization,GO:0000149//SNARE binding;GO:0005515//protein binding;GO:0005484//SNAP receptor activity,K13813//Phagosome
23676,0,0,0,0,0,3,1,181,19,0,0,0,"SMPX;small muscle protein, X-linked",GO:0043034//costamere;GO:0005927//muscle tendon junction;GO:0005634//nucleus;GO:0031430//M band,GO:0006941//striated muscle contraction,-,-
23677,0,28,1,27,144,0,0,1,15,0,32,0,SH3BP4;SH3-domain binding protein 4,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005905//coated pit;GO:0070062//extracellular vesicular exosome;GO:0030136//clathrin-coated vesicle,GO:0030308//negative regulation of cell growth;GO:0008285//negative regulation of cell proliferation;GO:0034260//negative regulation of GTPase activity;GO:0032007//negative regulation of TOR signaling;GO:0006897//endocytosis;GO:0061462//protein localization to lysosome;GO:0010508//positive regulation of autophagy;GO:0050790//regulation of catalytic activity;GO:0043090//amino acid import;GO:0071230//cellular response to amino acid stimulus,GO:0017016//Ras GTPase binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0005092//GDP-dissociation inhibitor activity,K05704//Regulation of actin cytoskeleton;Epithelial cell signaling in Helicobacter pylori infection;VEGF signaling pathway;Focal adhesion;Adherens junction;ErbB signaling pathway;Endocytosis;Bacterial invasion of epithelial cells;GnRH signaling pathway;Chemokine signaling pathway;Tight junction;GABAergic synapse;Gap junction;Shigellosis;Tuberculosis;K05705//Adherens junction;Tight junction
23678,0,0,0,0,8,0,0,49,0,0,0,0,"SGK3;serum/glucocorticoid regulated kinase family, member 3",-,-,-,-
23682,0,0,0,0,1,0,0,3,21,0,4,0,"RAB38;RAB38, member RAS oncogene family",GO:0005829//cytosol;GO:0031905//early endosome lumen;GO:0042470//melanosome;GO:0016020//membrane;GO:0045335//phagocytic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0032438//melanosome organization;GO:0015031//protein transport;GO:0060155//platelet dense granule organization;GO:0072657//protein localization to membrane;GO:0006184//GTP catabolic process;GO:0035646//endosome to melanosome transport;GO:0007264//small GTPase mediated signal transduction;GO:0090383//phagosome acidification,GO:0005515//protein binding;GO:0035612//AP-2 adaptor complex binding;GO:0030742//GTP-dependent protein binding;GO:0003924//GTPase activity;GO:0035651//AP-3 adaptor complex binding;GO:0005525//GTP binding;GO:0035650//AP-1 adaptor complex binding;GO:0032403//protein complex binding,-
23683,91,1,1,26,92,18,30,1,45,0,21,0,PRKD3;protein kinase D3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0016020//membrane,GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0004697//protein kinase C activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
23704,30,0,0,0,0,0,0,0,0,0,2,0,"KCNE4;potassium voltage-gated channel, Isk-related family, member 4",GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005249//voltage-gated potassium channel activity,-
23708,0,0,1,19,24,24,0,0,8,0,0,0,GSPT2;G1 to S phase transition 2,GO:0005829//cytosol,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0007049//cell cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006184//GTP catabolic process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K03267//mRNA surveillance pathway
23710,0,41,3,42,103,12,6,0,11,0,0,0,GABARAPL1;GABA(A) receptor-associated protein like 1,GO:0005622//intracellular;GO:0005874//microtubule;GO:0005776//autophagic vacuole;GO:0032590//dendrite membrane;GO:0005783//endoplasmic reticulum;GO:0030659//cytoplasmic vesicle membrane;GO:0005794//Golgi apparatus;GO:0032839//dendrite cytoplasm;GO:0044297//cell body,GO:0006914//autophagy,GO:0050811//GABA receptor binding;GO:0048487//beta-tubulin binding;GO:0005515//protein binding,K08341//Regulation of autophagy;GABAergic synapse
23729,0,0,0,0,22,13,0,67,25,0,0,0,SHPK;sedoheptulokinase,GO:0005737//cytoplasm,"GO:0035963//cellular response to interleukin-13;GO:0071222//cellular response to lipopolysaccharide;GO:0005975//carbohydrate metabolic process;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0016310//phosphorylation;GO:0071353//cellular response to interleukin-4;GO:0043030//regulation of macrophage activation;GO:0050727//regulation of inflammatory response",GO:0005524//ATP binding;GO:0050277//sedoheptulokinase activity,K11214//Carbon fixation in photosynthetic organisms
23731,0,0,1,0,11,55,36,5,31,0,1,335,TMEM245;transmembrane protein 245,GO:0016021//integral component of membrane,-,-,-
23732,0,0,0,0,0,0,0,0,25,0,0,0,FRRS1L;ferric-chelate reductase 1-like,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction,-,-,-
23741,0,16,2,46,136,0,2,0,13,0,0,0,EID1;EP300 interacting inhibitor of differentiation 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016235//aggresome;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0035065//regulation of histone acetylation;GO:0007049//cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003714//transcription corepressor activity;GO:0035035//histone acetyltransferase binding;GO:0035034//histone acetyltransferase regulator activity;GO:0005515//protein binding,-
23742,0,0,0,0,12,0,0,0,49,0,0,0,NPAP1;nuclear pore associated protein 1,GO:0005654//nucleoplasm;GO:0005637//nuclear inner membrane;GO:0070062//extracellular vesicular exosome,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,K14316//RNA transport
23743,0,0,0,0,0,0,0,0,12,0,1,0,BHMT2;betaine--homocysteine S-methyltransferase 2,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006577//amino-acid betaine metabolic process;GO:0071267//L-methionine salvage;GO:0032259//methylation;GO:0046500//S-adenosylmethionine metabolic process;GO:0033477//S-methylmethionine metabolic process,GO:0047150//betaine-homocysteine S-methyltransferase activity;GO:0008270//zinc ion binding;GO:0061627//S-methylmethionine-homocysteine S-methyltransferase activity;GO:0008898//S-adenosylmethionine-homocysteine S-methyltransferase activity,"K00544//Metabolic pathways;Cysteine and methionine metabolism;Glycine, serine and threonine metabolism"
23746,0,0,0,0,0,5,9,26,38,0,0,0,AIPL1;aryl hydrocarbon receptor interacting protein-like 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0001917//photoreceptor inner segment,"GO:0001895//retina homeostasis;GO:0030823//regulation of cGMP metabolic process;GO:0007603//phototransduction, visible light;GO:0006457//protein folding;GO:0043066//negative regulation of apoptotic process;GO:0007601//visual perception;GO:0018343//protein farnesylation",GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0001918//farnesylated protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K06965//mRNA surveillance pathway;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer
23753,0,0,0,0,0,0,0,0,7,0,0,0,SDF2L1;stromal cell-derived factor 2-like 1,GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane,-,-,K00728//Other types of O-glycan biosynthesis
23759,0,1,1,0,7,12,0,25,11,0,0,0,PPIL2;peptidylprolyl isomerase (cyclophilin)-like 2,GO:0005634//nucleus;GO:0005796//Golgi lumen;GO:0005730//nucleolus,GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0000413//protein peptidyl-prolyl isomerization;GO:0000209//protein polyubiquitination;GO:0006457//protein folding,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0034450//ubiquitin-ubiquitin ligase activity,K10598//Ubiquitin mediated proteolysis
23760,200,24,1,23,52,0,0,0,6,0,0,0,"PITPNB;phosphatidylinositol transfer protein, beta",GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane,GO:0015914//phospholipid transport;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0001701//in utero embryonic development;GO:0006644//phospholipid metabolic process,GO:0008289//lipid binding,K01106//Metabolic pathways;Insulin signaling pathway;Phosphatidylinositol signaling system;Inositol phosphate metabolism
23761,0,23,0,9,1,12,30,0,46,0,0,0,PISD;phosphatidylserine decarboxylase,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0044281//small molecule metabolic process,GO:0004609//phosphatidylserine decarboxylase activity,K01613//Glycerophospholipid metabolism;Metabolic pathways
23762,0,97,52,20,27,0,0,28,2,82,11,1,OSBP2;oxysterol binding protein 2,GO:0016020//membrane,GO:0006869//lipid transport,GO:0015485//cholesterol binding,K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K11447//Transcriptional misregulation in cancer
23764,0,0,0,0,15,27,0,0,6,0,0,0,MAFF;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F,GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0045604//regulation of epidermal cell differentiation;GO:0007567//parturition;GO:0001701//in utero embryonic development;GO:0007596//blood coagulation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
23765,0,0,0,0,10,0,14,167,62,0,8,0,IL17RA;interleukin 17 receptor A,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0019221//cytokine-mediated signaling pathway;GO:0072537//fibroblast activation;GO:0007166//cell surface receptor signaling pathway;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0032747//positive regulation of interleukin-23 production,GO:0030368//interleukin-17 receptor activity;GO:0005515//protein binding,K05164//Cytokine-cytokine receptor interaction
23766,0,0,0,0,0,0,0,0,18,0,1,0,"GABARAPL3;GABA(A) receptors associated protein like 3, pseudogene",GO:0005874//microtubule;GO:0031410//cytoplasmic vesicle;GO:0000421//autophagic vacuole membrane,GO:0006914//autophagy,-,K08341//Regulation of autophagy;GABAergic synapse
23767,26,0,0,28,0,0,18,0,28,0,0,0,FLRT3;fibronectin leucine rich transmembrane protein 3,GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space,GO:0007155//cell adhesion;GO:0035556//intracellular signal transduction;GO:0007411//axon guidance;GO:0050919//negative chemotaxis,"GO:0005057//receptor signaling protein activity;GO:0030674//protein binding, bridging;GO:0045499//chemorepellent activity",K07523//Axon guidance;K04660//TGF-beta signaling pathway
23768,98,0,0,0,0,26,16,0,43,0,0,2,FLRT2;fibronectin leucine rich transmembrane protein 2,GO:0005887//integral component of plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:0007411//axon guidance;GO:0035556//intracellular signal transduction;GO:0007155//cell adhesion;GO:0050919//negative chemotaxis;GO:2001222//regulation of neuron migration,"GO:0045499//chemorepellent activity;GO:0030674//protein binding, bridging;GO:0005057//receptor signaling protein activity",K07523//Axon guidance
23769,0,0,0,0,0,0,0,143,8,1,31,0,FLRT1;fibronectin leucine rich transmembrane protein 1,GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane,GO:0035556//intracellular signal transduction;GO:0007155//cell adhesion,"GO:0005057//receptor signaling protein activity;GO:0030674//protein binding, bridging",-
23770,0,19,2,19,25,0,25,1,28,0,0,0,"FKBP8;FK506 binding protein 8, 38kDa",GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0016020//membrane,GO:0006915//apoptotic process;GO:0035264//multicellular organism growth;GO:0010468//regulation of gene expression;GO:0061077//chaperone-mediated protein folding;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0021904//dorsal/ventral neural tube patterning;GO:0030513//positive regulation of BMP signaling pathway;GO:0000413//protein peptidyl-prolyl isomerization;GO:0016032//viral process;GO:0001708//cell fate specification;GO:0007224//smoothened signaling pathway;GO:0043010//camera-type eye development,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding,-
23780,14,0,0,0,17,0,1,0,24,0,20,0,"APOL2;apolipoprotein L, 2",GO:0005576//extracellular region;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0007275//multicellular organismal development;GO:0006629//lipid metabolic process;GO:0006953//acute-phase response;GO:0060135//maternal process involved in female pregnancy;GO:0042157//lipoprotein metabolic process,GO:0008035//high-density lipoprotein particle binding;GO:0005102//receptor binding;GO:0008289//lipid binding,K14480//African trypanosomiasis
23782,0,0,1,0,0,0,0,0,0,0,0,0,"AP1B1P1;adaptor-related protein complex 1, beta 1 subunit pseudogene 1",-,-,-,K12392//Lysosome
23783,224,0,0,0,0,0,22,0,20,0,5,0,"ANKRD62P1-PARP4P3;ANKRD62P1-PARP4P3 readthrough, transcribed pseudogene",-,-,-,K10798//NF-kappa B signaling pathway;Base excision repair
23784,0,43,182,286,167,16,53,1,9,4,82,1,"POTEH;POTE ankyrin domain family, member H",-,-,-,K08803//Bladder cancer;Pathways in cancer
23786,0,63,0,14,39,19,8,0,50,0,8,0,BCL2L13;BCL2-like 13 (apoptosis facilitator),GO:0005634//nucleus;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0006915//apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process,K15485//Legionellosis
23787,0,20,1,8,63,0,44,62,9,91,8,0,MTCH1;mitochondrial carrier 1,GO:0005743//mitochondrial inner membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0045161//neuronal ion channel clustering;GO:0009966//regulation of signal transduction;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006810//transport;GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding,-
23788,89,1,0,61,197,39,6,0,12,0,0,0,MTCH2;mitochondrial carrier 2,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0070585//protein localization to mitochondrion;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process,-,-
238,28,0,0,0,0,41,16,0,68,318,14,0,ALK;anaplastic lymphoma receptor tyrosine kinase,GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0008283//cell proliferation;GO:0000187//activation of MAPK activity;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042981//regulation of apoptotic process;GO:0038061//NIK/NF-kappaB signaling;GO:0016310//phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0048666//neuron development,GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding,-
239,94,40,18,81,45,0,0,0,30,0,83,0,ALOX12;arachidonate 12-lipoxygenase,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005829//cytosol;GO:0042383//sarcolemma;GO:0070062//extracellular vesicular exosome,GO:0051901//positive regulation of mitochondrial depolarization;GO:0019369//arachidonic acid metabolic process;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0007568//aging;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0090331//negative regulation of platelet aggregation;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0030307//positive regulation of cell growth;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010595//positive regulation of endothelial cell migration;GO:0072593//reactive oxygen species metabolic process;GO:0008284//positive regulation of cell proliferation;GO:1901751//leukotriene A4 metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0071396//cellular response to lipid;GO:0006928//cellular component movement;GO:2001306//lipoxin B4 biosynthetic process;GO:0061436//establishment of skin barrier;GO:0042554//superoxide anion generation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0051122//hepoxilin biosynthetic process;GO:0045909//positive regulation of vasodilation;GO:0045785//positive regulation of cell adhesion;GO:2001303//lipoxin A4 biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0043651//linoleic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0019395//fatty acid oxidation;GO:0045766//positive regulation of angiogenesis,"GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0004052//arachidonate 12-lipoxygenase activity;GO:0047977//hepoxilin-epoxide hydrolase activity;GO:0016165//linoleate 13S-lipoxygenase activity;GO:0051120//hepoxilin A3 synthase activity",K00458//Arachidonic acid metabolism;Metabolic pathways;Serotonergic synapse
2395,60,0,1,0,24,0,30,41,98,0,0,0,FXN;frataxin,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0006119//oxidative phosphorylation;GO:0018283//iron incorporation into metallo-sulfur cluster;GO:0046621//negative regulation of organ growth;GO:0051349//positive regulation of lyase activity;GO:0051347//positive regulation of transferase activity;GO:0009060//aerobic respiration;GO:0016540//protein autoprocessing;GO:0048554//positive regulation of metalloenzyme activity;GO:0010722//regulation of ferrochelatase activity;GO:0007005//mitochondrion organization;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0030307//positive regulation of cell growth;GO:0070301//cellular response to hydrogen peroxide;GO:0051353//positive regulation of oxidoreductase activity;GO:0006811//ion transport;GO:0006783//heme biosynthetic process;GO:0007628//adult walking behavior;GO:0009792//embryo development ending in birth or egg hatching;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0040015//negative regulation of multicellular organism growth;GO:0006879//cellular iron ion homeostasis;GO:0010039//response to iron ion;GO:0044281//small molecule metabolic process;GO:0019230//proprioception,"GO:0051536//iron-sulfur cluster binding;GO:0005515//protein binding;GO:0008199//ferric iron binding;GO:0004322//ferroxidase activity;GO:0008198//ferrous iron binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0034986//iron chaperone activity",K11447//Transcriptional misregulation in cancer
24,35,0,0,5,0,110,0,39,57,0,4,0,"ABCA4;ATP-binding cassette, sub-family A (ABC1), member 4",GO:0097381//photoreceptor disc membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane,"GO:0001523//retinoid metabolic process;GO:0007601//visual perception;GO:0006200//ATP catabolic process;GO:0045494//photoreceptor cell maintenance;GO:0045332//phospholipid translocation;GO:0007603//phototransduction, visible light;GO:0006810//transport;GO:0006649//phospholipid transfer to membrane;GO:0055085//transmembrane transport","GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding;GO:0005215//transporter activity;GO:0004012//phospholipid-translocating ATPase activity",K05644//ABC transporters
240,109,0,1,21,0,0,2,0,14,0,8,0,ALOX5;arachidonate 5-lipoxygenase,GO:0005635//nuclear envelope;GO:0016363//nuclear matrix;GO:0031965//nuclear membrane;GO:0005829//cytosol;GO:0005641//nuclear envelope lumen;GO:0005615//extracellular space,GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0002540//leukotriene production involved in inflammatory response;GO:0006691//leukotriene metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0004051//arachidonate 5-lipoxygenase activity,K00461//Metabolic pathways;Arachidonic acid metabolism;Toxoplasmosis;Serotonergic synapse
241,0,0,0,0,0,17,0,0,28,0,0,0,ALOX5AP;arachidonate 5-lipoxygenase-activating protein,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope,GO:0019372//lipoxygenase pathway;GO:2001300//lipoxin metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0002675//positive regulation of acute inflammatory response;GO:0070207//protein homotrimerization;GO:0019369//arachidonic acid metabolic process;GO:0071277//cellular response to calcium ion;GO:0002540//leukotriene production involved in inflammatory response;GO:0044281//small molecule metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0006691//leukotriene metabolic process,GO:0004464//leukotriene-C4 synthase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0050544//arachidonic acid binding;GO:0004364//glutathione transferase activity;GO:0047485//protein N-terminus binding;GO:0019899//enzyme binding;GO:0008047//enzyme activator activity;GO:0004602//glutathione peroxidase activity,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
24137,0,0,0,0,0,19,0,0,55,0,0,0,KIF4A;kinesin family member 4A,GO:0005694//chromosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0016363//nuclear matrix,GO:0008089//anterograde axon cargo transport;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0007411//axon guidance;GO:0006996//organelle organization;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation,GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding,-
24138,0,44,0,46,76,16,43,139,0,0,20,1,IFIT5;interferon-induced protein with tetratricopeptide repeats 5,GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0045177//apical part of cell,GO:0045087//innate immune response;GO:0051607//defense response to virus,GO:0044822//poly(A) RNA binding;GO:0003727//single-stranded RNA binding;GO:0003723//RNA binding;GO:0000049//tRNA binding,K14217//Herpes simplex infection;Hepatitis C
24139,0,65,0,0,4,9,0,45,134,1,3,349,EML2;echinoderm microtubule associated protein like 2,GO:0072686//mitotic spindle;GO:0005875//microtubule associated complex;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007605//sensory perception of sound;GO:0031115//negative regulation of microtubule polymerization;GO:0007601//visual perception,GO:0015631//tubulin binding;GO:0005102//receptor binding;GO:0008022//protein C-terminus binding;GO:0008017//microtubule binding,-
24140,0,0,0,1,13,0,0,0,10,0,0,0,FTSJ1;FtsJ RNA methyltransferase homolog 1 (E. coli),GO:0005737//cytoplasm,GO:0002181//cytoplasmic translation,GO:0008175//tRNA methyltransferase activity,-
24141,83,0,0,0,0,0,0,88,16,158,0,0,"LAMP5;lysosomal-associated membrane protein family, member 5",GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0032590//dendrite membrane;GO:0032584//growth cone membrane;GO:0031901//early endosome membrane;GO:0055038//recycling endosome membrane,-,-,K06528//Lysosome;Tuberculosis;Phagosome
24142,0,0,1,0,0,0,0,0,0,0,0,0,NAT6;N-acetyltransferase 6 (GCN5-related),GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0008080//N-acetyltransferase activity,-
24144,0,267,21,339,344,14,32,65,134,0,504,0,TFIP11;tuftelin interacting protein 11,GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005681//spliceosomal complex;GO:0071008//U2-type post-mRNA release spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0016607//nuclear speck,"GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing;GO:0000390//spliceosomal complex disassembly;GO:0006355//regulation of transcription, DNA-templated;GO:0031214//biomineral tissue development",GO:0003677//DNA binding,-
24145,0,0,0,0,0,0,44,0,15,0,0,0,PANX1;pannexin 1,GO:0005789//endoplasmic reticulum membrane;GO:0043234//protein complex;GO:0005921//gap junction;GO:0032059//bleb;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,"GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0007268//synaptic transmission;GO:0002931//response to ischemia;GO:0006812//cation transport;GO:0034214//protein hexamerization;GO:0033198//response to ATP;GO:0045087//innate immune response;GO:0050717//positive regulation of interleukin-1 alpha secretion",GO:0051015//actin filament binding;GO:0055077//gap junction hemi-channel activity;GO:0022840//leak channel activity;GO:0046982//protein heterodimerization activity;GO:0044325//ion channel binding;GO:0005262//calcium channel activity;GO:0002020//protease binding;GO:0005102//receptor binding;GO:0097110//scaffold protein binding,-
24146,0,0,51,0,8,0,0,0,0,306,0,2,CLDN15;claudin 15,GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane,GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//tight junction assembly;GO:0006811//ion transport,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
24147,0,0,0,0,0,0,0,0,25,0,0,0,FJX1;four jointed box 1 (Drosophila),GO:0005615//extracellular space,GO:0010842//retina layer formation,-,-
24148,88,44,1,11,20,0,18,0,34,0,10,59,PRPF6;pre-mRNA processing factor 6,GO:0005681//spliceosomal complex;GO:0005682//U5 snRNP;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0071001//U4/U6 snRNP;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly;GO:0006403//RNA localization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0050681//androgen receptor binding,K12855//Spliceosome
24149,0,0,1,5,25,0,0,0,6,0,12,0,ZNF318;zinc finger protein 318,GO:0005634//nucleus,"GO:0007126//meiotic nuclear division;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,-
242,252,34,8,42,56,0,0,10,38,2,153,0,"ALOX12B;arachidonate 12-lipoxygenase, 12R type",GO:0005829//cytosol,GO:0061436//establishment of skin barrier;GO:0010628//positive regulation of gene expression;GO:0070257//positive regulation of mucus secretion;GO:0019372//lipoxygenase pathway;GO:0051122//hepoxilin biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0043651//linoleic acid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0006497//protein lipidation;GO:0046513//ceramide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0043410//positive regulation of MAPK cascade,"GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:1990136//linoleate 9S-lipoxygenase activity;GO:0005515//protein binding;GO:0004052//arachidonate 12-lipoxygenase activity;GO:0005506//iron ion binding",K08021//Metabolic pathways;Arachidonic acid metabolism;Serotonergic synapse
2444,0,1,0,29,63,33,21,0,56,0,0,0,FRK;fyn-related Src family tyrosine kinase,GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding,-
245,23,0,0,11,0,5,0,0,6,0,0,0,ALOX12P2;arachidonate 12-lipoxygenase pseudogene 2,-,-,-,K00458//Arachidonic acid metabolism;Metabolic pathways;Serotonergic synapse
245711,0,0,51,68,26,0,0,0,3,0,30,0,SPDYA;speedy/RINGO cell cycle regulator family member A,GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0007140//male meiosis;GO:0006974//cellular response to DNA damage stimulus;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle,GO:0019901//protein kinase binding,K08694//Progesterone-mediated oocyte maturation;Oocyte meiosis
245802,0,0,0,0,0,0,0,0,0,66,0,0,"MS4A6E;membrane-spanning 4-domains, subfamily A, member 6E",GO:0016021//integral component of membrane,-,-,-
245806,0,0,0,0,0,0,0,0,0,12,6,0,VGLL2;vestigial-like family member 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007519//skeletal muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity,-
245812,0,0,0,0,0,0,0,0,0,0,1,0,CNPY4;canopy FGF signaling regulator 4,GO:0005576//extracellular region,-,GO:0005102//receptor binding,"K00552//Glycine, serine and threonine metabolism"
245911,0,0,0,0,12,0,0,0,0,0,11,0,"DEFB108B;defensin, beta 108B",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245912,117,0,0,0,0,0,0,0,0,0,0,0,"DEFB109P1;defensin, beta 109, pseudogene 1",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245913,0,0,0,0,0,0,0,0,16,0,0,0,"DEFB110;defensin, beta 110 locus",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245915,0,0,0,7,0,0,0,0,0,0,0,0,"DEFB112;defensin, beta 112",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245927,0,0,0,0,0,0,0,0,0,0,0,339,"DEFB113;defensin, beta 113",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245929,0,0,0,0,0,0,0,0,34,0,0,0,"DEFB115;defensin, beta 115",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245930,0,0,0,0,0,17,0,0,12,0,0,0,"DEFB116;defensin, beta 116",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245934,0,0,0,0,0,0,0,0,1,0,0,0,"DEFB121;defensin, beta 121",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245936,0,0,0,0,0,0,0,0,40,0,0,0,"DEFB123;defensin, beta 123",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245937,0,0,0,0,0,0,0,0,30,0,0,0,"DEFB124;defensin, beta 124",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245939,0,0,0,0,0,0,0,0,22,0,5,0,"DEFB128;defensin, beta 128",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
245972,51,0,0,0,0,0,38,0,31,0,0,0,"ATP6V0D2;ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2","GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0016324//apical plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome",GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0051701//interaction with host;GO:0055085//transmembrane transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0008286//insulin receptor signaling pathway,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005515//protein binding,K02146//Oxidative phosphorylation;Metabolic pathways;Vibrio cholerae infection;Lysosome;Epithelial cell signaling in Helicobacter pylori infection;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome;Tuberculosis;Synaptic vesicle cycle
245973,1,222,151,407,579,0,76,185,36,5,1047,14,"ATP6V1C2;ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2","GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0005765//lysosomal membrane",GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0030177//positive regulation of Wnt signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport,"GO:0046983//protein dimerization activity;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism",K02148//Synaptic vesicle cycle;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Oxidative phosphorylation;Metabolic pathways
246,0,0,0,0,0,0,0,0,32,149,8,324,ALOX15;arachidonate 15-lipoxygenase,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005811//lipid particle,GO:0042060//wound healing;GO:0010811//positive regulation of cell-substrate adhesion;GO:0043277//apoptotic cell clearance;GO:0071277//cellular response to calcium ion;GO:0001503//ossification;GO:1901074//regulation of engulfment of apoptotic cell;GO:0044281//small molecule metabolic process;GO:0006691//leukotriene metabolic process;GO:0002820//negative regulation of adaptive immune response;GO:0035358//regulation of peroxisome proliferator activated receptor signaling pathway;GO:0051122//hepoxilin biosynthetic process;GO:0019372//lipoxygenase pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0030282//bone mineralization;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006954//inflammatory response;GO:2001303//lipoxin A4 biosynthetic process;GO:0030838//positive regulation of actin filament polymerization;GO:0034976//response to endoplasmic reticulum stress;GO:0035963//cellular response to interleukin-13,"GO:0050473//arachidonate 15-lipoxygenase activity;GO:0005515//protein binding;GO:0004052//arachidonate 12-lipoxygenase activity;GO:0005506//iron ion binding;GO:0097260//eoxin A4 synthase activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K00460//Serotonergic synapse;Metabolic pathways;Linoleic acid metabolism;Arachidonic acid metabolism
246126,0,1,0,10,0,0,0,0,0,0,0,0,"TXLNGY;taxilin gamma pseudogene, Y-linked",-,-,GO:0019905//syntaxin binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K06106//Shigellosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction
246175,0,108,2,106,305,2,14,0,16,0,0,0,"CNOT6L;CCR4-NOT transcription complex, subunit 6-like",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex;GO:0005829//cytosol,"GO:0008284//positive regulation of cell proliferation;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0006351//transcription, DNA-templated;GO:0061157//mRNA destabilization;GO:0006417//regulation of translation;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004535//poly(A)-specific ribonuclease activity,K12603//RNA degradation
246176,0,0,0,0,0,0,7,55,18,63,8,0,GAS2L2;growth arrest-specific 2 like 2,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0001725//stress fiber,GO:0007026//negative regulation of microtubule depolymerization;GO:0007050//cell cycle arrest;GO:0001578//microtubule bundle formation,GO:0008093//cytoskeletal adaptor activity;GO:0008017//microtubule binding;GO:0051015//actin filament binding,-
246181,0,0,0,0,16,0,25,0,56,0,0,0,AKR7L;aldo-keto reductase family 7-like,GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K15303//Metabolism of xenobiotics by cytochrome P450
246182,0,0,0,0,0,0,0,0,5,0,0,0,"AKR7A2P1;aldo-keto reductase family 7, member A2 pseudogene 1",-,-,-,K15303//Metabolism of xenobiotics by cytochrome P450
246184,0,0,0,5,2,7,0,0,14,0,0,0,CDC26;cell division cycle 26,GO:0005829//cytosol;GO:0005680//anaphase-promoting complex;GO:0005654//nucleoplasm,GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,K03359//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Cell cycle
246213,0,0,8,0,0,0,0,3,11,0,1,0,"SLC17A8;solute carrier family 17 (vesicular glutamate transporter), member 8",GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0043005//neuron projection;GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0007605//sensory perception of sound;GO:0006836//neurotransmitter transport;GO:0015813//L-glutamate transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity;GO:0005313//L-glutamate transmembrane transporter activity,K12302//Retrograde endocannabinoid signaling;Synaptic vesicle cycle;Nicotine addiction;Glutamatergic synapse
246243,114,1,0,0,21,0,1,0,2,0,0,0,RNASEH1;ribonuclease H1,GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0006264//mitochondrial DNA replication;GO:0006401//RNA catabolic process;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0003676//nucleic acid binding;GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0042803//protein homodimerization activity;GO:0004540//ribonuclease activity,K03469//Metabolic pathways;Lipopolysaccharide biosynthesis;DNA replication
246269,0,41,0,0,41,0,0,0,11,0,0,0,LACE1;lactation elevated 1,GO:0005739//mitochondrion,-,GO:0005524//ATP binding,-
246329,5,0,0,0,0,21,0,38,9,0,6,0,STAC3;SH3 and cysteine rich domain 3,-,GO:0035556//intracellular signal transduction;GO:0048741//skeletal muscle fiber development,GO:0042802//identical protein binding;GO:0046872//metal ion binding,K04705//Jak-STAT signaling pathway;Endocytosis;K08010//Leukocyte transendothelial migration;Phagosome;Osteoclast differentiation;Leishmaniasis;K07366//T cell receptor signaling pathway
246330,61,41,38,61,2,0,0,0,17,9,34,0,PELI3;pellino E3 ubiquitin protein ligase family member 3,GO:0005829//cytosol,GO:0045751//negative regulation of Toll signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0050829//defense response to Gram-negative bacterium;GO:0008063//Toll signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
246721,1,0,0,0,0,23,0,0,2,0,0,257,POLR2J2;polymerase (RNA) II (DNA directed) polypeptide J2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated",GO:0003899//DNA-directed RNA polymerase activity;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,K03008//Huntington's disease;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase
246744,0,0,0,0,0,0,12,0,0,0,0,0,STH;saitohin,GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
246778,0,0,0,0,0,0,0,0,19,0,0,0,IL27;interleukin 27,GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:0045625//regulation of T-helper 1 cell differentiation;GO:0050688//regulation of defense response to virus;GO:0009617//response to bacterium;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0045087//innate immune response;GO:0042129//regulation of T cell proliferation,GO:0045523//interleukin-27 receptor binding;GO:0005102//receptor binding;GO:0005125//cytokine activity,-
247,9,6,5,64,111,0,0,96,77,0,32,0,"ALOX15B;arachidonate 15-lipoxygenase, type B",GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005622//intracellular,GO:0008285//negative regulation of cell proliferation;GO:0030336//negative regulation of cell migration;GO:0030850//prostate gland development;GO:0043651//linoleic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045618//positive regulation of keratinocyte differentiation;GO:0006629//lipid metabolic process;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0045926//negative regulation of growth;GO:0006915//apoptotic process;GO:0051122//hepoxilin biosynthetic process;GO:0019372//lipoxygenase pathway;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0045786//negative regulation of cell cycle;GO:0090197//positive regulation of chemokine secretion;GO:0030856//regulation of epithelial cell differentiation,GO:0016165//linoleate 13S-lipoxygenase activity;GO:0008289//lipid binding;GO:0005509//calcium ion binding;GO:0005506//iron ion binding;GO:0050473//arachidonate 15-lipoxygenase activity;GO:0036403//arachidonate 8(S)-lipoxygenase activity,K08022//Arachidonic acid metabolism;Metabolic pathways;Serotonergic synapse
2475,0,0,0,32,66,34,7,56,151,0,15,0,MTOR;mechanistic target of rapamycin (serine/threonine kinase),GO:0012505//endomembrane system;GO:0005741//mitochondrial outer membrane;GO:0031932//TORC2 complex;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016605//PML body;GO:0005829//cytosol;GO:0005764//lysosome;GO:0031931//TORC1 complex;GO:0005789//endoplasmic reticulum membrane,GO:0006950//response to stress;GO:0040007//growth;GO:0018107//peptidyl-threonine phosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032314//regulation of Rac GTPase activity;GO:0030163//protein catabolic process;GO:0010628//positive regulation of gene expression;GO:0048015//phosphatidylinositol-mediated signaling;GO:0016049//cell growth;GO:0051897//positive regulation of protein kinase B signaling;GO:0045087//innate immune response;GO:0031929//TOR signaling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0031669//cellular response to nutrient levels;GO:0010831//positive regulation of myotube differentiation;GO:0046889//positive regulation of lipid biosynthetic process;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0043610//regulation of carbohydrate utilization;GO:0007584//response to nutrient;GO:0043200//response to amino acid;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0010592//positive regulation of lamellipodium assembly;GO:0006468//protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0010507//negative regulation of autophagy;GO:0005979//regulation of glycogen biosynthetic process;GO:0045727//positive regulation of translation;GO:0030838//positive regulation of actin filament polymerization;GO:0016310//phosphorylation;GO:0032095//regulation of response to food;GO:0051496//positive regulation of stress fiber assembly;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0046777//protein autophosphorylation;GO:0045792//negative regulation of cell size;GO:0045859//regulation of protein kinase activity;GO:0032956//regulation of actin cytoskeleton organization;GO:0001938//positive regulation of endothelial cell proliferation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031998//regulation of fatty acid beta-oxidation;GO:0031295//T cell costimulation;GO:0007281//germ cell development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0016242//negative regulation of macroautophagy;GO:0031529//ruffle organization;GO:0071456//cellular response to hypoxia,GO:0001030//RNA polymerase III type 1 promoter DNA binding;GO:0001032//RNA polymerase III type 3 promoter DNA binding;GO:0019904//protein domain specific binding;GO:0016301//kinase activity;GO:0008144//drug binding;GO:0005524//ATP binding;GO:0001031//RNA polymerase III type 2 promoter DNA binding;GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0004674//protein serine/threonine kinase activity;GO:0001156//TFIIIC-class transcription factor binding;GO:0043022//ribosome binding,K07203//Adipocytokine signaling pathway;mTOR signaling pathway;Glioma;ErbB signaling pathway;Type II diabetes mellitus;Pathways in cancer;Acute myeloid leukemia;Insulin signaling pathway;Meiosis - yeast;Prostate cancer
248,100,0,0,0,24,0,0,0,34,0,1,0,"ALPI;alkaline phosphatase, intestinal",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0016311//dephosphorylation,GO:0008270//zinc ion binding;GO:0004035//alkaline phosphatase activity;GO:0000287//magnesium ion binding;GO:0002020//protease binding,K01077//Two-component system;Microbial metabolism in diverse environments;Metabolic pathways;Arginine and proline metabolism;Biosynthesis of secondary metabolites;Aminobenzoate degradation;Folate biosynthesis
2483,3,0,0,0,0,13,0,0,29,0,1,0,FRG1;FSHD region gene 1,GO:0015030//Cajal body;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus,"GO:0000398//mRNA splicing, via spliceosome;GO:0006364//rRNA processing",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
2487,0,0,36,0,0,14,0,0,0,105,0,0,FRZB;frizzled-related protein,GO:0005737//cytoplasm;GO:0032589//neuron projection membrane;GO:0016020//membrane;GO:0005615//extracellular space,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0014033//neural crest cell differentiation;GO:0061037//negative regulation of cartilage development;GO:0010721//negative regulation of cell development;GO:0030308//negative regulation of cell growth;GO:0007420//brain development;GO:0070367//negative regulation of hepatocyte differentiation;GO:0007409//axonogenesis;GO:0060056//mammary gland involution;GO:0001501//skeletal system development;GO:0008406//gonad development;GO:0060429//epithelium development;GO:0001944//vasculature development;GO:0043065//positive regulation of apoptotic process;GO:0061053//somite development;GO:0090103//cochlea morphogenesis;GO:0016055//Wnt signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0060029//convergent extension involved in organogenesis;GO:0030178//negative regulation of Wnt signaling pathway,GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity,K02185//Wnt signaling pathway
2488,0,0,0,0,0,0,24,0,0,0,0,0,"FSHB;follicle stimulating hormone, beta polypeptide",GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0042699//follicle-stimulating hormone signaling pathway;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016486//peptide hormone processing;GO:0007565//female pregnancy;GO:0007292//female gamete generation;GO:0008284//positive regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060011//Sertoli cell proliferation;GO:0045670//regulation of osteoclast differentiation;GO:0006701//progesterone biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0030335//positive regulation of cell migration;GO:0045780//positive regulation of bone resorption,GO:0005179//hormone activity;GO:0005515//protein binding,K05250//Neuroactive ligand-receptor interaction;GnRH signaling pathway
249,385,0,0,0,0,65,0,0,11,151,5,0,"ALPL;alkaline phosphatase, liver/bone/kidney",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0031225//anchored component of membrane,GO:0003006//developmental process involved in reproduction;GO:0071407//cellular response to organic cyclic compound;GO:0032496//response to lipopolysaccharide;GO:0016311//dephosphorylation;GO:0001501//skeletal system development;GO:0046677//response to antibiotic;GO:0051384//response to glucocorticoid;GO:0071529//cementum mineralization;GO:0033280//response to vitamin D;GO:0001958//endochondral ossification;GO:0001649//osteoblast differentiation,GO:0016462//pyrophosphatase activity;GO:0004035//alkaline phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K01077//Folate biosynthesis;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Aminobenzoate degradation;Microbial metabolism in diverse environments;Metabolic pathways;Two-component system
2491,0,0,0,8,0,14,0,0,7,0,0,0,CENPI;centromere protein I,GO:0000776//kinetochore;GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0007548//sex differentiation;GO:0000278//mitotic cell cycle;GO:0034080//CENP-A containing nucleosome assembly;GO:0006334//nucleosome assembly,GO:0005515//protein binding,-
2492,2,0,0,0,0,0,0,34,30,0,10,0,FSHR;follicle stimulating hormone receptor,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008585//female gonad development;GO:0008406//gonad development;GO:0007292//female gamete generation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0042699//follicle-stimulating hormone signaling pathway,GO:0004963//follicle-stimulating hormone receptor activity;GO:0005515//protein binding,K04247//Neuroactive ligand-receptor interaction
2494,0,0,0,0,20,5,47,0,46,0,17,0,"NR5A2;nuclear receptor subfamily 5, group A, member 2",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045070//positive regulation of viral genome replication;GO:0031018//endocrine pancreas development;GO:0030522//intracellular receptor signaling pathway;GO:0042127//regulation of cell proliferation;GO:0009790//embryo development;GO:0042592//homeostatic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0042632//cholesterol homeostasis;GO:0010467//gene expression;GO:0008206//bile acid metabolic process",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005543//phospholipid binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K08027//Maturity onset diabetes of the young
2495,0,264,3,221,639,23,1,0,11,0,0,1,"FTH1;ferritin, heavy polypeptide 1",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0008043//intracellular ferritin complex;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006826//iron ion transport;GO:0055085//transmembrane transport;GO:0048147//negative regulation of fibroblast proliferation;GO:0008285//negative regulation of cell proliferation;GO:0061024//membrane organization;GO:0006880//intracellular sequestering of iron ion;GO:0055114//oxidation-reduction process;GO:0006955//immune response;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006879//cellular iron ion homeostasis,GO:0004322//ferroxidase activity;GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0005506//iron ion binding,K00522//Mineral absorption;Porphyrin and chlorophyll metabolism
25,81,18,0,21,23,34,90,117,52,0,0,0,"ABL1;ABL proto-oncogene 1, non-receptor tyrosine kinase",GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0051353//positive regulation of oxidoreductase activity;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0030100//regulation of endocytosis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0010506//regulation of autophagy;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045087//innate immune response;GO:0006979//response to oxidative stress;GO:0007155//cell adhesion;GO:0006914//autophagy;GO:0007596//blood coagulation;GO:0030155//regulation of cell adhesion;GO:1900275//negative regulation of phospholipase C activity;GO:0007050//cell cycle arrest;GO:0034599//cellular response to oxidative stress;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030036//actin cytoskeleton organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006355//regulation of transcription, DNA-templated;GO:0006464//cellular protein modification process;GO:0051149//positive regulation of muscle cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:2001020//regulation of response to DNA damage stimulus;GO:0006975//DNA damage induced protein phosphorylation;GO:0042692//muscle cell differentiation;GO:0042770//signal transduction in response to DNA damage;GO:2000145//regulation of cell motility;GO:0007067//mitotic nuclear division;GO:0006298//mismatch repair;GO:0051882//mitochondrial depolarization;GO:0006974//cellular response to DNA damage stimulus",GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0004713//protein tyrosine kinase activity;GO:0008022//protein C-terminus binding;GO:0004672//protein kinase activity;GO:0070064//proline-rich region binding;GO:0004515//nicotinate-nucleotide adenylyltransferase activity;GO:0017124//SH3 domain binding;GO:0003677//DNA binding;GO:0019905//syntaxin binding;GO:0030145//manganese ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0051019//mitogen-activated protein kinase binding;GO:0003785//actin monomer binding;GO:0005524//ATP binding,K06619//Shigellosis;Pathways in cancer;Axon guidance;Cell cycle;Pathogenic Escherichia coli infection;ErbB signaling pathway;Neurotrophin signaling pathway;Chronic myeloid leukemia;Viral myocarditis
250,41,0,0,0,0,1,14,0,74,95,0,0,"ALPP;alkaline phosphatase, placental",GO:0031225//anchored component of membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0016311//dephosphorylation,GO:0008270//zinc ion binding;GO:0004035//alkaline phosphatase activity;GO:0000287//magnesium ion binding,K01077//Two-component system;Microbial metabolism in diverse environments;Metabolic pathways;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Aminobenzoate degradation;Folate biosynthesis
251,0,0,0,0,0,0,0,0,0,0,12,0,"ALPPL2;alkaline phosphatase, placental-like 2",GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0004035//alkaline phosphatase activity,K01077//Two-component system;Metabolic pathways;Microbial metabolism in diverse environments;Arginine and proline metabolism;Biosynthesis of secondary metabolites;Aminobenzoate degradation;Folate biosynthesis
2512,0,46,0,33,112,0,0,96,0,0,1,4,"FTL;ferritin, light polypeptide",GO:0016020//membrane;GO:0008043//intracellular ferritin complex;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0055072//iron ion homeostasis;GO:0061024//membrane organization;GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport;GO:0006826//iron ion transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0008219//cell death,GO:0005506//iron ion binding;GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K13625//Mineral absorption;Porphyrin and chlorophyll metabolism
2515,0,0,0,0,24,20,0,0,31,0,0,0,ADAM2;ADAM metallopeptidase domain 2,GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0007342//fusion of sperm to egg plasma membrane;GO:0032504//multicellular organism reproduction;GO:0030534//adult behavior;GO:0007155//cell adhesion;GO:0006508//proteolysis;GO:0007339//binding of sperm to zona pellucida;GO:0008542//visual learning;GO:0007338//single fertilization,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0005178//integrin binding,-
2516,0,0,0,0,0,0,0,35,1,0,0,0,"NR5A1;nuclear receptor subfamily 5, group A, member 1",GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0010467//gene expression;GO:0030325//adrenal gland development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0009888//tissue development;GO:0007267//cell-cell signaling;GO:0007538//primary sex determination;GO:0008584//male gonad development;GO:0001553//luteinization;GO:0043401//steroid hormone mediated signaling pathway;GO:2000195//negative regulation of female gonad development;GO:2000020//positive regulation of male gonad development;GO:0030522//intracellular receptor signaling pathway;GO:0030154//cell differentiation;GO:0042445//hormone metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050810//regulation of steroid biosynthetic process;GO:0010259//multicellular organismal aging;GO:0051457//maintenance of protein location in nucleus,GO:0005515//protein binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0005543//phospholipid binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003690//double-stranded DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0019899//enzyme binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding,-
2517,104,0,0,8,0,0,15,85,0,0,1,0,"FUCA1;fucosidase, alpha-L- 1, tissue",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0006027//glycosaminoglycan catabolic process;GO:0016139//glycoside catabolic process;GO:0006004//fucose metabolic process,GO:0042806//fucose binding;GO:0004560//alpha-L-fucosidase activity,"K01206//Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Metabolic pathways;Pentose phosphate pathway;Alanine, aspartate and glutamate metabolism;Other glycan degradation;Lysosome;Purine metabolism"
2519,56,27,0,25,3,0,21,0,10,0,13,0,"FUCA2;fucosidase, alpha-L- 2, plasma",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,GO:2000535//regulation of entry of bacterium into host cell;GO:0016139//glycoside catabolic process;GO:0006004//fucose metabolic process;GO:0009617//response to bacterium,GO:0004560//alpha-L-fucosidase activity;GO:0042806//fucose binding,"K01206//Lysosome;Purine metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Pentose phosphate pathway;Other glycan degradation;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments"
2520,0,0,0,0,0,0,0,0,20,0,0,0,GAST;gastrin,GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0005179//hormone activity,K13768//Gastric acid secretion
2521,0,0,0,0,51,12,0,0,4,0,0,18,FUS;FUS RNA binding protein,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome;GO:0008219//cell death",GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K13098//Transcriptional misregulation in cancer
2523,0,0,0,0,0,0,10,34,29,0,0,0,"FUT1;fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)",GO:0005887//integral component of plasma membrane;GO:0032580//Golgi cisterna membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process,GO:0008107//galactoside 2-alpha-L-fucosyltransferase activity,K00718//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
2524,0,0,0,16,24,0,0,0,3,0,0,0,FUT2;fucosyltransferase 2 (secretor status included),GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:0006486//protein glycosylation;GO:0005975//carbohydrate metabolic process,GO:0008107//galactoside 2-alpha-L-fucosyltransferase activity,K00718//Metabolic pathways;Glycosphingolipid biosynthesis - globo series;Glycosphingolipid biosynthesis - lacto and neolacto series
2525,0,0,0,0,0,8,0,0,2,0,0,0,"FUT3;fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)",GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0036065//fucosylation;GO:0006486//protein glycosylation;GO:0009988//cell-cell recognition;GO:0009312//oligosaccharide biosynthetic process,GO:0046920//alpha-(1->3)-fucosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity,K00716//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways;K07633//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
2526,98,0,0,6,0,0,0,0,0,0,0,0,"FUT4;fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0071944//cell periphery,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process,GO:0046920//alpha-(1->3)-fucosyltransferase activity,K07632//Other types of O-glycan biosynthesis;Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
2527,0,0,0,0,0,4,0,0,0,0,0,0,"FUT5;fucosyltransferase 5 (alpha (1,3) fucosyltransferase)",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation,GO:0046920//alpha-(1->3)-fucosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity,K07633//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series;K00716//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
2528,0,1,0,0,0,18,0,50,10,0,0,0,"FUT6;fucosyltransferase 6 (alpha (1,3) fucosyltransferase)",GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane,GO:0042355//L-fucose catabolic process;GO:0036065//fucosylation;GO:0006486//protein glycosylation,GO:0046920//alpha-(1->3)-fucosyltransferase activity;GO:0017060//3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity,K07634//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series;K07633//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
252839,0,0,1,0,0,0,0,1,0,0,0,0,TMEM9;transmembrane protein 9,GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005770//late endosome;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
252884,0,0,0,4,0,34,7,0,23,107,8,0,ZNF396;zinc finger protein 396,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
2529,0,0,0,0,0,11,0,0,0,0,0,0,"FUT7;fucosyltransferase 7 (alpha (1,3) fucosyltransferase)",GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,"GO:0006486//protein glycosylation;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0002522//leukocyte migration involved in immune response;GO:0036065//fucosylation;GO:0042355//L-fucose catabolic process",GO:0046920//alpha-(1->3)-fucosyltransferase activity,K07635//Metabolic pathways;Other types of O-glycan biosynthesis;Glycosphingolipid biosynthesis - lacto and neolacto series
252969,0,6,0,31,45,0,41,0,7,0,41,0,NEIL2;nei endonuclease VIII-like 2 (E. coli),GO:0005876//spindle microtubule;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair;GO:0006284//base-excision repair","GO:0003684//damaged DNA binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0008270//zinc ion binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0008017//microtubule binding",K10568//Base excision repair
252983,0,0,0,4,0,0,0,0,0,0,0,0,STXBP4;syntaxin binding protein 4,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0045111//intermediate filament cytoskeleton,GO:0006974//cellular response to DNA damage stimulus;GO:0010838//positive regulation of keratinocyte proliferation;GO:0015758//glucose transport;GO:0006605//protein targeting;GO:0050821//protein stabilization;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:0008286//insulin receptor signaling pathway,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
252995,0,10,0,0,1,7,0,23,17,0,5,0,FNDC5;fibronectin type III domain containing 5,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005778//peroxisomal membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0014850//response to muscle activity;GO:0090336//positive regulation of brown fat cell differentiation,GO:0005179//hormone activity,-
2530,128,0,0,12,0,9,0,0,57,167,40,0,"FUT8;fucosyltransferase 8 (alpha (1,6) fucosyltransferase)",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0016477//cell migration;GO:0043687//post-translational protein modification;GO:0007229//integrin-mediated signaling pathway;GO:0036071//N-glycan fucosylation;GO:0043112//receptor metabolic process;GO:0044267//cellular protein metabolic process;GO:0033578//protein glycosylation in Golgi;GO:0006491//N-glycan processing;GO:0007585//respiratory gaseous exchange;GO:0001701//in utero embryonic development;GO:0009312//oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0046368//GDP-L-fucose metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006487//protein N-linked glycosylation;GO:0042355//L-fucose catabolic process,GO:0008424//glycoprotein 6-alpha-L-fucosyltransferase activity;GO:0017124//SH3 domain binding,K00717//Transcriptional misregulation in cancer;Glycosaminoglycan biosynthesis - keratan sulfate;N-Glycan biosynthesis;Metabolic pathways
253012,0,0,0,0,6,0,0,0,42,0,5,0,HEPACAM2;HEPACAM family member 2,GO:0005813//centrosome;GO:0005819//spindle;GO:0030496//midbody;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization,GO:0005515//protein binding,-
253017,0,0,0,0,0,2,0,0,36,0,0,0,"TECRL;trans-2,3-enoyl-CoA reductase-like",GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0006629//lipid metabolic process;GO:0055114//oxidation-reduction process,"GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors",K10258//Fatty acid elongation;Biosynthesis of secondary metabolites;Biosynthesis of unsaturated fatty acids
253018,0,0,0,0,0,0,0,0,0,129,17,0,HCG27;HLA complex group 27 (non-protein coding),-,-,-,-
2531,0,0,0,1,18,7,32,0,87,259,0,1,KDSR;3-ketodihydrosphingosine reductase,GO:0005789//endoplasmic reticulum membrane;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006665//sphingolipid metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0006666//3-keto-sphinganine metabolic process,GO:0047560//3-dehydrosphinganine reductase activity,K04708//Sphingolipid metabolism;Metabolic pathways
253128,67,0,0,0,0,0,0,0,11,0,10,0,LINC00612;long intergenic non-protein coding RNA 612,-,-,-,-
253143,8,62,0,29,65,13,0,32,15,0,0,0,PRR14L;proline rich 14-like,-,-,-,K01613//Metabolic pathways;Glycerophospholipid metabolism
253152,0,0,0,0,0,26,0,0,9,0,0,0,EPHX4;epoxide hydrolase 4,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K08726//Arachidonic acid metabolism;Metabolic pathways;Peroxisome;K08059//Antigen processing and presentation
253190,0,0,0,0,2,0,0,0,62,109,6,0,SERHL2;serine hydrolase-like 2,GO:0048471//perinuclear region of cytoplasm;GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
2532,0,0,0,0,0,26,0,0,12,0,0,0,ACKR1;atypical chemokine receptor 1 (Duffy blood group),GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0055037//recycling endosome,GO:0006954//inflammatory response;GO:0070098//chemokine-mediated signaling pathway;GO:0006952//defense response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032642//regulation of chemokine production,GO:0019957//C-C chemokine binding;GO:0004930//G-protein coupled receptor activity;GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity,K06574//Malaria
253260,0,1,0,20,106,30,9,0,62,178,0,0,"RICTOR;RPTOR independent companion of MTOR, complex 2",GO:0031932//TORC2 complex;GO:0005829//cytosol,GO:0030838//positive regulation of actin filament polymerization;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0032008//positive regulation of TOR signaling;GO:0032314//regulation of Rac GTPase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0009790//embryo development;GO:0045087//innate immune response;GO:0051897//positive regulation of protein kinase B signaling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0031929//TOR signaling;GO:0051896//regulation of protein kinase B signaling;GO:0031532//actin cytoskeleton reorganization;GO:0032956//regulation of actin cytoskeleton organization;GO:0001938//positive regulation of endothelial cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0043022//ribosome binding,K08267//mTOR signaling pathway
2533,0,0,0,0,0,34,0,0,21,0,0,0,FYB;FYN binding protein,GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0007165//signal transduction;GO:0006607//NLS-bearing protein import into nucleus;GO:0035556//intracellular signal transduction;GO:0006955//immune response,GO:0005102//receptor binding;GO:0032403//protein complex binding;GO:0005515//protein binding,-
253314,0,0,0,0,0,0,0,0,24,0,0,0,EIF4E1B;eukaryotic translation initiation factor 4E family member 1B,GO:0005737//cytoplasm;GO:0005845//mRNA cap binding complex,GO:0006413//translational initiation;GO:0006417//regulation of translation,GO:0003743//translation initiation factor activity,K03259//RNA transport;Insulin signaling pathway;mTOR signaling pathway
2534,0,0,0,0,0,0,12,0,7,0,0,0,"FYN;FYN proto-oncogene, Src family tyrosine kinase",GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0005739//mitochondrion;GO:0045121//membrane raft;GO:0005829//cytosol,GO:0050690//regulation of defense response to virus by virus;GO:0050852//T cell receptor signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0007596//blood coagulation;GO:0001764//neuron migration;GO:0007631//feeding behavior;GO:0030168//platelet activation;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0035556//intracellular signal transduction;GO:0008360//regulation of cell shape;GO:1900182//positive regulation of protein localization to nucleus;GO:0006816//calcium ion transport;GO:0050798//activated T cell proliferation;GO:0048813//dendrite morphogenesis;GO:0045087//innate immune response;GO:0010629//negative regulation of gene expression;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0042177//negative regulation of protein catabolic process;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0050900//leukocyte migration;GO:0071375//cellular response to peptide hormone stimulus;GO:0030900//forebrain development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007612//learning;GO:0007411//axon guidance;GO:0045471//response to ethanol;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042493//response to drug;GO:0031295//T cell costimulation;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0001664//G-protein coupled receptor binding;GO:0042610//CD8 receptor binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0044325//ion channel binding;GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0046875//ephrin receptor binding;GO:0015631//tubulin binding;GO:0004713//protein tyrosine kinase activity;GO:0005515//protein binding;GO:0042609//CD4 receptor binding;GO:0042608//T cell receptor binding;GO:0001948//glycoprotein binding;GO:0070851//growth factor receptor binding;GO:0005524//ATP binding;GO:0051428//peptide hormone receptor binding,K05703//Cholinergic synapse;Fc epsilon RI signaling pathway;Axon guidance;Viral myocarditis;Prion diseases;Osteoclast differentiation;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Focal adhesion;Measles;Adherens junction;Pathogenic Escherichia coli infection
253430,0,1,0,12,0,30,0,0,23,0,20,0,IPMK;inositol polyphosphate multikinase,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0001841//neural tube formation;GO:0016310//phosphorylation;GO:0032958//inositol phosphate biosynthetic process,"GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0000823//inositol-1,4,5-trisphosphate 6-kinase activity;GO:0000824//inositol tetrakisphosphate 3-kinase activity",K00328//Inositol phosphate metabolism
253461,0,51,0,77,98,10,70,0,43,0,54,0,ZBTB38;zinc finger and BTB domain containing 38,GO:0005634//nucleus;GO:0072562//blood microparticle,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0008327//methyl-CpG binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2535,0,0,0,0,0,49,14,0,0,0,0,0,FZD2;frizzled class receptor 2,GO:0016021//integral component of membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0032589//neuron projection membrane;GO:0045177//apical part of cell;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005737//cytoplasm,"GO:0030855//epithelial cell differentiation;GO:0001944//vasculature development;GO:0008406//gonad development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030182//neuron differentiation;GO:0090103//cochlea morphogenesis;GO:0060022//hard palate development;GO:0003149//membranous septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0007420//brain development;GO:0060070//canonical Wnt signaling pathway;GO:0030825//positive regulation of cGMP metabolic process;GO:0007608//sensory perception of smell;GO:0007409//axonogenesis;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0060119//inner ear receptor cell development;GO:0003150//muscular septum morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007267//cell-cell signaling",GO:0004930//G-protein coupled receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding;GO:0017147//Wnt-protein binding,K02235//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Pathways in cancer
253512,0,35,29,22,31,32,0,57,49,0,7,0,"SLC25A30;solute carrier family 25, member 30",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006839//mitochondrial transport,-,-
253558,0,0,0,0,0,0,51,0,64,0,0,0,LCLAT1;lysocardiolipin acyltransferase 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006654//phosphatidic acid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0007275//multicellular organismal development;GO:0035965//cardiolipin acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13513//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism
253559,0,0,0,0,0,1,23,0,12,0,0,0,CADM2;cell adhesion molecule 2,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0030424//axon,GO:0007420//brain development;GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization,-,-
253582,0,0,0,0,0,7,0,0,14,0,0,0,TMEM244;transmembrane protein 244,GO:0016021//integral component of membrane,-,-,-
253635,8,0,0,0,31,0,17,0,20,15,0,0,GPATCH11;G patch domain containing 11,-,-,GO:0003676//nucleic acid binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K11447//Transcriptional misregulation in cancer
253639,68,0,0,0,1,0,26,0,22,0,0,0,ZNF620;zinc finger protein 620,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
253650,0,0,0,15,0,14,0,0,13,0,7,0,ANKRD18A;ankyrin repeat domain 18A,-,-,-,-
2537,0,0,0,0,0,6,37,0,30,0,4,0,"IFI6;interferon, alpha-inducible protein 6",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051902//negative regulation of mitochondrial depolarization;GO:0006955//immune response;GO:0060337//type I interferon signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005515//protein binding,-
253714,125,0,23,0,1,18,33,0,85,55,0,0,"MMS22L;MMS22-like, DNA repair protein",GO:0043596//nuclear replication fork;GO:0035101//FACT complex;GO:0042555//MCM complex,GO:0031297//replication fork processing;GO:0000724//double-strand break repair via homologous recombination,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
253724,0,0,0,0,1,0,0,0,39,0,7,0,GNN;Grp94 neighboring nucleotidase pseudogene,GO:0005737//cytoplasm,-,-,-
253725,0,65,36,33,59,0,0,69,28,0,17,0,"FAM21C;family with sequence similarity 21, member C",GO:0031901//early endosome membrane;GO:0005768//endosome;GO:0071203//WASH complex;GO:0005886//plasma membrane;GO:0005769//early endosome,"GO:0042147//retrograde transport, endosome to Golgi",GO:0005515//protein binding,-
253738,94,0,0,0,0,0,1,0,26,1,0,129,EBF3;early B-cell factor 3,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
253769,0,0,0,0,0,0,10,0,29,0,0,0,WDR27;WD repeat domain 27,GO:0005730//nucleolus;GO:0005634//nucleus,-,-,-
253782,3,0,0,0,38,0,20,60,0,43,0,0,CERS6;ceramide synthase 6,GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0046513//ceramide biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0050291//sphingosine N-acyltransferase activity;GO:0003677//DNA binding,K04710//Metabolic pathways;Sphingolipid metabolism
2538,125,0,0,0,0,15,38,0,13,1,0,0,"G6PC;glucose-6-phosphatase, catalytic subunit",GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0046415//urate metabolic process;GO:0042632//cholesterol homeostasis;GO:0010468//regulation of gene expression;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0006641//triglyceride metabolic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0042593//glucose homeostasis;GO:0044281//small molecule metabolic process;GO:0006094//gluconeogenesis;GO:0008202//steroid metabolic process;GO:0015758//glucose transport;GO:0016311//dephosphorylation;GO:0035264//multicellular organism growth;GO:0055085//transmembrane transport;GO:0015760//glucose-6-phosphate transport,"GO:0004346//glucose-6-phosphatase activity;GO:0042301//phosphate ion binding;GO:0016773//phosphotransferase activity, alcohol group as acceptor",K01084//Galactose metabolism;Insulin signaling pathway;Metabolic pathways;Adipocytokine signaling pathway;Carbohydrate digestion and absorption;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis
253827,0,0,0,0,0,39,26,0,22,0,0,51,MSRB3;methionine sulfoxide reductase B3,GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion,GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process;GO:0030091//protein repair,GO:0008270//zinc ion binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity,-
253832,67,0,0,0,12,0,0,0,21,0,0,0,"ZDHHC20;zinc finger, DHHC-type containing 20",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
2539,0,62,0,6,21,9,0,53,31,30,39,0,G6PD;glucose-6-phosphate dehydrogenase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0043249//erythrocyte maturation;GO:0006629//lipid metabolic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0019322//pentose biosynthetic process;GO:0044281//small molecule metabolic process;GO:0010734//negative regulation of protein glutathionylation;GO:0043523//regulation of neuron apoptotic process;GO:0032094//response to food;GO:0045471//response to ethanol;GO:0046390//ribose phosphate biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0005975//carbohydrate metabolic process;GO:0034599//cellular response to oxidative stress;GO:0006740//NADPH regeneration;GO:0021762//substantia nigra development;GO:0006739//NADP metabolic process;GO:0055114//oxidation-reduction process;GO:0006749//glutathione metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0006098//pentose-phosphate shunt;GO:0001816//cytokine production",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0050661//NADP binding;GO:0004345//glucose-6-phosphate dehydrogenase activity;GO:0005536//glucose binding,K00036//Microbial metabolism in diverse environments;Pentose phosphate pathway;Metabolic pathways;Biosynthesis of secondary metabolites;Glutathione metabolism
253935,0,0,0,0,0,0,42,0,2,0,0,0,ANGPTL5;angiopoietin-like 5,GO:0005576//extracellular region,-,-,-
253943,0,28,0,83,222,0,0,0,5,0,0,0,"YTHDF3;YTH domain family, member 3",-,-,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:1990247//N6-methyladenosine-containing RNA binding,-
253959,0,0,0,0,11,0,0,3,6,0,6,0,"RALGAPA1;Ral GTPase activating protein, alpha subunit 1 (catalytic)",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0032859//activation of Ral GTPase activity",GO:0017123//Ral GTPase activator activity;GO:0046982//protein heterodimerization activity,K07207//Insulin signaling pathway;mTOR signaling pathway;p53 signaling pathway
253980,89,0,0,0,12,0,0,3,0,0,0,0,KCTD13;potassium channel tetramerization domain containing 13,GO:0005634//nucleus;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0006260//DNA replication;GO:0035024//negative regulation of Rho protein signal transduction;GO:0045740//positive regulation of DNA replication;GO:0043149//stress fiber assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0051260//protein homooligomerization;GO:0016477//cell migration,GO:0019904//protein domain specific binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042802//identical protein binding;GO:0017049//GTP-Rho binding,-
253982,0,0,0,0,0,0,0,0,36,0,14,0,ASPHD1;aspartate beta-hydroxylase domain containing 1,GO:0016021//integral component of membrane,GO:0018193//peptidyl-amino acid modification;GO:0055114//oxidation-reduction process,GO:0051213//dioxygenase activity,-
254013,29,0,0,3,1,0,0,0,36,0,1,0,METTL20;methyltransferase like 20,GO:0005737//cytoplasm,GO:0006479//protein methylation,GO:0008276//protein methyltransferase activity,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction
254048,30,0,0,66,243,8,87,56,71,0,0,0,UBN2;ubinuclein 2,GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
254050,0,0,0,0,0,0,0,0,9,0,0,0,LRRC43;leucine rich repeat containing 43,-,-,-,-
254065,196,1,0,0,35,53,64,0,72,0,0,0,BRWD3;bromodomain and WD repeat domain containing 3,-,GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization,-,-
254099,0,0,0,0,0,0,0,1,0,0,0,0,LINC01342;long intergenic non-protein coding RNA 1342,-,-,-,-
254102,245,0,0,0,0,0,0,0,56,0,8,0,EHBP1L1;EH domain binding protein 1-like 1,GO:0016020//membrane,-,-,K05699//Regulation of actin cytoskeleton;Systemic lupus erythematosus;Amoebiasis;Focal adhesion;Adherens junction;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration;K06115//Tight junction
254122,0,0,33,0,0,38,0,0,14,0,1,0,SNX32;sorting nexin 32,GO:0005768//endosome,GO:0006886//intracellular protein transport,GO:0035091//phosphatidylinositol binding,-
254158,0,0,0,0,0,0,0,0,11,0,3,0,CXorf58;chromosome X open reading frame 58,-,-,-,-
254170,0,0,1,11,44,23,0,0,52,0,0,0,FBXO33;F-box protein 33,-,GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
254173,0,0,0,0,0,0,76,0,11,116,0,0,"TTLL10;tubulin tyrosine ligase-like family, member 10",-,GO:0018094//protein polyglycylation,GO:0005515//protein binding;GO:0070735//protein-glycine ligase activity,"K00273//Glycine, serine and threonine metabolism;Penicillin and cephalosporin biosynthesis;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Peroxisome;Metabolic pathways;K15010//Glutamatergic synapse"
254187,17,0,0,0,0,0,65,0,60,0,0,0,"TSGA10IP;testis specific, 10 interacting protein",-,-,-,-
2542,0,0,1,0,0,15,0,10,46,0,21,0,"SLC37A4;solute carrier family 37 (glucose-6-phosphate transporter), member 4",GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0042593//glucose homeostasis;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0015758//glucose transport;GO:0006810//transport;GO:0055085//transmembrane transport;GO:0015760//glucose-6-phosphate transport,GO:0005215//transporter activity;GO:0015152//glucose-6-phosphate transmembrane transporter activity,K08171//Carbohydrate digestion and absorption
254225,0,146,231,658,990,19,0,103,8,1,253,0,RNF169;ring finger protein 169,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0035861//site of double-strand break;GO:0005886//plasma membrane,GO:2000780//negative regulation of double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0016567//protein ubiquitination,GO:0070530//K63-linked polyubiquitin binding;GO:0016874//ligase activity;GO:0008270//zinc ion binding;GO:0031491//nucleosome binding,-
254228,0,0,0,0,0,0,0,0,20,0,0,0,"FAM26E;family with sequence similarity 26, member E",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
254240,41,0,0,0,0,21,1,0,24,0,0,0,BPIFC;BPI fold containing family C,GO:0005576//extracellular region,-,GO:0001530//lipopolysaccharide binding;GO:0005543//phospholipid binding,K05399//Salmonella infection;NF-kappa B signaling pathway;Tuberculosis;Toll-like receptor signaling pathway;K08761//PPAR signaling pathway
254251,214,0,0,14,69,0,51,0,72,2,2,0,LCORL;ligand dependent nuclear receptor corepressor-like,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding,K06678//Cell cycle - yeast
254263,46,0,0,4,0,0,0,0,0,0,0,0,CNIH2;cornichon family AMPA receptor auxiliary protein 2,GO:0005789//endoplasmic reticulum membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0043198//dendritic shaft;GO:0014069//postsynaptic density;GO:0043197//dendritic spine,"GO:0035249//synaptic transmission, glutamatergic;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0051668//localization within membrane;GO:0035556//intracellular signal transduction;GO:0042391//regulation of membrane potential",GO:0005515//protein binding,-
254268,85,223,1122,274,0,15,13,374,197,0,71,0,AKNAD1;AKNA domain containing 1,GO:0005737//cytoplasm,-,-,-
254272,0,0,0,0,0,0,3,0,15,0,0,0,"TBC1D28;TBC1 domain family, member 28",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,-
254295,0,14,0,0,0,0,7,0,24,0,0,0,PHYHD1;phytanoyl-CoA dioxygenase domain containing 1,-,GO:0055114//oxidation-reduction process,GO:0051213//dioxygenase activity;GO:0046872//metal ion binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K01539//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K00477//Peroxisome
2543,7,0,0,0,0,0,0,0,9,0,12,0,GAGE1;G antigen 1,-,GO:0006968//cellular defense response,-,K11447//Transcriptional misregulation in cancer
254394,6,24,0,11,30,28,24,0,35,14,16,0,MCM9;minichromosome maintenance complex component 9,GO:0097362//MCM8-MCM9 complex;GO:0005634//nucleus,GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006974//cellular response to DNA damage stimulus;GO:0007292//female gamete generation,GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding,-
254427,0,1,38,13,39,0,0,30,15,1,0,0,PROSER2;proline and serine rich 2,-,-,-,-
254428,0,0,0,0,49,22,2,0,37,0,3,0,"SLC41A1;solute carrier family 41 (magnesium transporter), member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport,GO:0008324//cation transmembrane transporter activity,-
254528,0,0,0,11,32,0,0,0,0,0,41,0,MEIOB;meiosis specific with OB domains,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005694//chromosome,"GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0007140//male meiosis;GO:0009566//fertilization;GO:0000724//double-strand break repair via homologous recombination;GO:0007129//synapsis;GO:0000738//DNA catabolic process, exonucleolytic;GO:0000712//resolution of meiotic recombination intermediates",GO:0003697//single-stranded DNA binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0003682//chromatin binding,K07466//Fanconi anemia pathway;Mismatch repair;Homologous recombination;Nucleotide excision repair;DNA replication
254531,0,0,0,0,2,0,0,0,0,0,0,0,LPCAT4;lysophosphatidylcholine acyltransferase 4,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006654//phosphatidic acid biosynthetic process,GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0005509//calcium ion binding;GO:0047166//1-alkenylglycerophosphoethanolamine O-acyltransferase activity;GO:0071617//lysophospholipid acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity,K13512//Metabolic pathways;Glycerophospholipid metabolism;Ether lipid metabolism
254552,0,0,0,0,0,0,0,0,0,0,10,0,NUDT8;nudix (nucleoside diphosphate linked moiety X)-type motif 8,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K01529//Purine metabolism
2547,0,58,0,64,255,1,0,0,11,0,2,0,XRCC6;X-ray repair complementing defective repair in Chinese hamster cells 6,GO:0070419//nonhomologous end joining complex;GO:0016020//membrane;GO:0043564//Ku70:Ku80 complex;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071481//cellular response to X-ray;GO:0075713//establishment of integrated proviral latency;GO:0071475//cellular hyperosmotic salinity response;GO:0006351//transcription, DNA-templated;GO:0006266//DNA ligation;GO:0000723//telomere maintenance;GO:0007420//brain development;GO:0032508//DNA duplex unwinding;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0033151//V(D)J recombination;GO:0006281//DNA repair;GO:0050769//positive regulation of neurogenesis;GO:0006302//double-strand break repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006303//double-strand break repair via nonhomologous end joining",GO:0004003//ATP-dependent DNA helicase activity;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0003691//double-stranded telomeric DNA binding;GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003684//damaged DNA binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K10884//Non-homologous end-joining
254773,89,0,0,0,0,0,0,0,7,0,0,0,LYG2;lysozyme G-like 2,GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process;GO:0009253//peptidoglycan catabolic process,GO:0003796//lysozyme activity,-
254778,0,0,0,0,0,13,0,0,0,0,0,0,C8orf46;chromosome 8 open reading frame 46,-,-,-,-
254783,0,0,0,0,0,0,0,0,53,0,0,14,"OR6C74;olfactory receptor, family 6, subfamily C, member 74",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
254786,0,0,0,0,0,0,0,0,12,0,0,0,"OR6C3;olfactory receptor, family 6, subfamily C, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2548,0,0,0,0,0,22,0,0,9,0,0,461,"GAA;glucosidase, alpha; acid",GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0005980//glycogen catabolic process;GO:0050885//neuromuscular process controlling balance;GO:0046716//muscle cell cellular homeostasis;GO:0007040//lysosome organization;GO:0003007//heart morphogenesis;GO:0002026//regulation of the force of heart contraction;GO:0000023//maltose metabolic process;GO:0006006//glucose metabolic process;GO:0002086//diaphragm contraction;GO:0050884//neuromuscular process controlling posture;GO:0009888//tissue development;GO:0060048//cardiac muscle contraction;GO:0005985//sucrose metabolic process;GO:0043181//vacuolar sequestering;GO:0007626//locomotory behavior,GO:0032450//maltose alpha-glucosidase activity;GO:0030246//carbohydrate binding,K12316//Lysosome;Starch and sucrose metabolism;Galactose metabolism;Metabolic pathways
254827,0,2,24,0,9,0,16,0,42,96,0,0,NAALADL2;N-acetylated alpha-linked acidic dipeptidase-like 2,GO:0016021//integral component of membrane,-,-,K14592//Vitamin digestion and absorption
254863,0,0,0,0,0,0,0,0,11,0,0,0,TMEM256;transmembrane protein 256,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
254887,0,0,49,5,1,0,11,0,36,46,0,0,"ZDHHC23;zinc finger, DHHC-type containing 23",GO:0016021//integral component of membrane,GO:0072659//protein localization to plasma membrane;GO:0018345//protein palmitoylation,GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
254896,0,0,0,0,0,25,0,0,0,0,0,0,LOC254896;uncharacterized LOC254896,-,-,-,K04722//Influenza A;Measles;p53 signaling pathway;Cytokine-cytokine receptor interaction;Apoptosis;Natural killer cell mediated cytotoxicity
2549,0,0,0,15,47,26,0,0,5,1,0,0,GAB1;GRB2-associated binding protein 1,GO:0005829//cytosol,GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007507//heart development;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0008283//cell proliferation;GO:0008544//epidermis development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0070102//interleukin-6-mediated signaling pathway;GO:0030334//regulation of cell migration;GO:0007257//activation of JUN kinase activity;GO:0060711//labyrinthine layer development;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0006979//response to oxidative stress,GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0005070//SH3/SH2 adaptor activity,K09593//ErbB signaling pathway;Renal cell carcinoma;Bacterial invasion of epithelial cells;Neurotrophin signaling pathway
254910,0,0,0,0,0,0,0,0,1,0,0,0,LCE5A;late cornified envelope 5A,-,GO:0031424//keratinization,-,-
255022,0,0,0,0,0,23,18,110,57,0,0,0,CALHM1;calcium homeostasis modulator 1,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0015867//ATP transport;GO:0006812//cation transport;GO:0050917//sensory perception of umami taste;GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0050913//sensory perception of bitter taste;GO:0050916//sensory perception of sweet taste;GO:0051260//protein homooligomerization,GO:0042802//identical protein binding;GO:0005262//calcium channel activity;GO:0005227//calcium activated cation channel activity;GO:0005244//voltage-gated ion channel activity,-
255027,6,0,0,0,0,0,0,0,0,0,0,1,MPV17L;MPV17 mitochondrial membrane protein-like,GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane;GO:0005777//peroxisome,GO:0010730//negative regulation of hydrogen peroxide biosynthetic process;GO:0072593//reactive oxygen species metabolic process;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,GO:0005102//receptor binding,K13349//Peroxisome
255043,231,0,0,0,0,0,0,0,0,0,0,0,TMEM86B;transmembrane protein 86B,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0046485//ether lipid metabolic process,GO:0047409//alkenylglycerophosphoethanolamine hydrolase activity;GO:0047408//alkenylglycerophosphocholine hydrolase activity,-
255057,0,0,0,0,0,36,0,1,14,0,8,0,C19orf26;chromosome 19 open reading frame 26,GO:0016021//integral component of membrane,-,-,-
255061,0,0,0,0,0,20,0,0,47,0,4,0,TAC4;tachykinin 4 (hemokinin),GO:0005576//extracellular region,GO:0046878//positive regulation of saliva secretion;GO:0008217//regulation of blood pressure;GO:0007217//tachykinin receptor signaling pathway,GO:0005102//receptor binding,-
2551,0,137,140,77,216,0,0,167,64,0,55,0,"GABPA;GA binding protein transcription factor, alpha subunit 60kDa",GO:0005730//nucleolus;GO:0000790//nuclear chromatin;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0001701//in utero embryonic development;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding,-
255101,91,37,0,11,9,0,59,0,27,251,22,34,CCDC108;coiled-coil domain containing 108,GO:0016021//integral component of membrane,-,GO:0005198//structural molecule activity;GO:0044822//poly(A) RNA binding,-
255104,0,1,0,6,42,0,24,7,23,0,9,0,TMCO4;transmembrane and coiled-coil domains 4,GO:0016021//integral component of membrane,-,-,-
255119,0,0,0,0,0,0,0,0,37,0,0,0,C4orf22;chromosome 4 open reading frame 22,-,-,-,-
255189,86,9,0,0,8,0,0,75,16,0,0,0,"PLA2G4F;phospholipase A2, group IVF",GO:0031982//vesicle;GO:0005765//lysosomal membrane;GO:0005829//cytosol;GO:0032587//ruffle membrane,GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0050482//arachidonic acid secretion;GO:0044281//small molecule metabolic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0071236//cellular response to antibiotic;GO:0006644//phospholipid metabolic process;GO:0071407//cellular response to organic cyclic compound;GO:0009395//phospholipid catabolic process;GO:0001516//prostaglandin biosynthetic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling,GO:0046872//metal ion binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0004622//lysophospholipase activity,K01047//GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;Metabolic pathways;Vascular smooth muscle contraction;Linoleic acid metabolism;MAPK signaling pathway;Glutamatergic synapse;Fc epsilon RI signaling pathway;Long-term depression;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism
255193,0,0,9,4,0,2,0,0,0,0,6,0,CSNK1G2-AS1;CSNK1G2 antisense RNA 1,-,-,-,-
255220,1,0,0,0,0,4,24,0,8,0,0,0,TXNDC8;thioredoxin domain containing 8 (spermatozoa),GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0001669//acrosomal vesicle;GO:0036126//sperm flagellum;GO:0005737//cytoplasm,GO:0001675//acrosome assembly;GO:0006662//glycerol ether metabolic process;GO:0007275//multicellular organismal development;GO:0045454//cell redox homeostasis;GO:0007283//spermatogenesis,GO:0015035//protein disulfide oxidoreductase activity,K03671//Pyrimidine metabolism;Selenocompound metabolism
255231,0,0,0,0,0,63,27,0,3,0,0,0,MCOLN2;mucolipin 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0034220//ion transmembrane transport,-,-
255239,0,0,0,0,0,16,0,57,16,0,9,0,ANKK1;ankyrin repeat and kinase domain containing 1,-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
255252,0,0,0,4,39,0,0,44,14,0,9,0,LRRC57;leucine rich repeat containing 57,GO:0070062//extracellular vesicular exosome,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
255275,0,0,0,1,0,0,0,0,0,0,8,0,MYADML2;myeloid-associated differentiation marker-like 2,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,-,-,-
2553,0,25,8,42,43,0,28,12,35,0,34,0,"GABPB1;GA binding protein transcription factor, beta subunit 1",GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
255324,0,0,0,0,0,5,0,0,0,0,19,0,EPGN;epithelial mitogen,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0001525//angiogenesis;GO:0043406//positive regulation of MAP kinase activity;GO:0008284//positive regulation of cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0045840//positive regulation of mitosis;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade,GO:0005154//epidermal growth factor receptor binding;GO:0004708//MAP kinase kinase activity;GO:0008083//growth factor activity,K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
255330,0,0,0,0,0,0,32,0,28,0,5,0,NUP210P1;nucleoporin 210kDa pseudogene 1,-,-,-,K14314//RNA transport
255349,0,0,0,0,0,0,0,0,6,0,0,0,TMEM211;transmembrane protein 211,GO:0016021//integral component of membrane,-,-,-
255374,0,0,0,0,0,12,0,115,12,0,4,602,MBLAC1;metallo-beta-lactamase domain containing 1,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,-
255394,0,0,0,15,9,0,0,0,32,0,0,0,"TCP11L2;t-complex 11, testis-specific-like 2",-,-,-,K13999//Protein processing in endoplasmic reticulum
2554,1,0,0,0,0,0,0,0,64,0,4,0,"GABRA1;gamma-aminobutyric acid (GABA) A receptor, alpha 1",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction,"GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0051932//synaptic transmission, GABAergic;GO:0055085//transmembrane transport",GO:0004890//GABA-A receptor activity;GO:0008144//drug binding;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity,K05175//Nicotine addiction;Morphine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
255403,0,1,1,8,9,12,0,0,37,0,11,0,ZNF718;zinc finger protein 718,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K06632//Cell cycle
255411,0,0,0,0,1,0,0,0,7,0,0,0,LINC00935;long intergenic non-protein coding RNA 935,-,-,-,-
255426,11,0,1,0,0,0,0,28,29,96,0,0,"RASGEF1C;RasGEF domain family, member 1C",GO:0005622//intracellular,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity,K08018//MAPK signaling pathway;K07376//Olfactory transduction;Salivary secretion;Gap junction;Long-term depression;Vascular smooth muscle contraction
255488,0,51,2,75,437,25,5,0,36,0,9,0,RNF144B;ring finger protein 144B,GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
2555,0,0,0,0,0,0,16,0,22,0,0,0,"GABRA2;gamma-aminobutyric acid (GABA) A receptor, alpha 2",GO:0030285//integral component of synaptic vesicle membrane;GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0030424//axon;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0001505//regulation of neurotransmitter levels;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0004890//GABA-A receptor activity;GO:0008503//benzodiazepine receptor activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity,K05175//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
255512,0,14,0,0,18,0,0,0,0,0,21,0,TOLLIP-AS1;TOLLIP antisense RNA 1 (head to head),-,-,-,-
255520,0,1,0,0,1,12,2,49,8,0,0,0,ELMOD2;ELMO/CED-12 domain containing 2,GO:0005856//cytoskeleton;GO:0016020//membrane,GO:0051607//defense response to virus;GO:0006909//phagocytosis;GO:0050688//regulation of defense response to virus;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,-
2556,109,0,0,0,0,0,0,0,14,0,0,0,"GABRA3;gamma-aminobutyric acid (GABA) A receptor, alpha 3",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex,GO:0006810//transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway,GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0008503//benzodiazepine receptor activity;GO:0004890//GABA-A receptor activity,K05175//Morphine addiction;Nicotine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
255626,0,0,0,0,12,0,0,0,0,0,0,0,"HIST1H2BA;histone cluster 1, H2ba",GO:0000786//nucleosome;GO:0005634//nucleus;GO:0019897//extrinsic component of plasma membrane;GO:0005654//nucleoplasm,"GO:0006954//inflammatory response;GO:0006334//nucleosome assembly;GO:0006337//nucleosome disassembly;GO:0031639//plasminogen activation;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0071229//cellular response to acid chemical;GO:0051099//positive regulation of binding;GO:0006325//chromatin organization;GO:0071674//mononuclear cell migration",GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Systemic lupus erythematosus;Alcoholism
255631,0,0,0,0,26,25,1,0,170,0,4,0,"COL24A1;collagen, type XXIV, alpha 1",GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0002244//hematopoietic progenitor cell differentiation,GO:0005201//extracellular matrix structural constituent,K06236//Protein digestion and absorption;Amoebiasis;Focal adhesion;ECM-receptor interaction
2557,0,0,0,0,0,40,31,0,74,0,8,125,"GABRA4;gamma-aminobutyric acid (GABA) A receptor, alpha 4",GO:0005887//integral component of plasma membrane;GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport;GO:2001023//regulation of response to drug;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007417//central nervous system development;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport,GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0008503//benzodiazepine receptor activity;GO:0004890//GABA-A receptor activity,K05175//GABAergic synapse;Morphine addiction;Nicotine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
255725,0,0,0,0,0,37,0,0,0,0,0,0,"OR52B2;olfactory receptor, family 52, subfamily B, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
255738,0,0,0,0,0,6,17,0,51,0,16,0,PCSK9;proprotein convertase subtilisin/kexin type 9,GO:0048471//perinuclear region of cytoplasm;GO:0005764//lysosome;GO:0005791//rough endoplasmic reticulum;GO:0005615//extracellular space;GO:0031232//extrinsic component of external side of plasma membrane;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005783//endoplasmic reticulum;GO:0030134//ER to Golgi transport vesicle;GO:0009986//cell surface;GO:0005770//late endosome,GO:0010469//regulation of receptor activity;GO:0001889//liver development;GO:0007041//lysosomal transport;GO:0001822//kidney development;GO:0043523//regulation of neuron apoptotic process;GO:0032869//cellular response to insulin stimulus;GO:0043525//positive regulation of neuron apoptotic process;GO:0008203//cholesterol metabolic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0006644//phospholipid metabolic process;GO:0042157//lipoprotein metabolic process;GO:0001920//negative regulation of receptor recycling;GO:0022008//neurogenesis;GO:0009267//cellular response to starvation;GO:0006915//apoptotic process;GO:0042632//cholesterol homeostasis;GO:0030182//neuron differentiation;GO:0006641//triglyceride metabolic process;GO:0032803//regulation of low-density lipoprotein particle receptor catabolic process;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0002092//positive regulation of receptor internalization,GO:0050750//low-density lipoprotein particle receptor binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0019871//sodium channel inhibitor activity;GO:0034190//apolipoprotein receptor binding;GO:0044822//poly(A) RNA binding;GO:0030169//low-density lipoprotein particle binding;GO:0005515//protein binding;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0043621//protein self-association;GO:0004252//serine-type endopeptidase activity,-
255743,0,0,1,15,109,20,0,67,0,0,0,0,NPNT;nephronectin,GO:0005578//proteinaceous extracellular matrix;GO:0030485//smooth muscle contractile fiber;GO:0034678//integrin alpha8-beta1 complex;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0001657//ureteric bud development;GO:0097195//pilomotor reflex;GO:0071356//cellular response to tumor necrosis factor;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0033631//cell-cell adhesion mediated by integrin;GO:0045987//positive regulation of smooth muscle contraction;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0045184//establishment of protein localization;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007160//cell-matrix adhesion,GO:0005509//calcium ion binding;GO:0005178//integrin binding,K06824//ECM-receptor interaction
255758,0,0,0,0,0,0,41,0,0,0,0,0,TCTEX1D2;Tctex1 domain containing 2,-,-,GO:0005515//protein binding,-
255762,0,0,0,0,0,1,0,0,5,0,0,216,PDZD9;PDZ domain containing 9,-,-,-,-
255798,0,0,0,0,0,24,0,0,28,0,0,0,C3orf43;chromosome 3 open reading frame 43,GO:0016021//integral component of membrane,-,-,-
2558,62,0,0,0,0,9,0,59,31,0,0,0,"GABRA5;gamma-aminobutyric acid (GABA) A receptor, alpha 5",GO:0032809//neuronal cell body membrane;GO:0034707//chloride channel complex;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0034220//ion transmembrane transport;GO:0060384//innervation;GO:0006810//transport;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0008306//associative learning;GO:0007268//synaptic transmission;GO:0090102//cochlea development;GO:0007420//brain development;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0007605//sensory perception of sound;GO:0043524//negative regulation of neuron apoptotic process;GO:0001662//behavioral fear response;GO:0007165//signal transduction;GO:0060119//inner ear receptor cell development,GO:0005215//transporter activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0004872//receptor activity;GO:0050811//GABA receptor binding;GO:0004890//GABA-A receptor activity,K05175//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
255809,0,0,0,0,0,0,0,0,20,0,0,0,C19orf38;chromosome 19 open reading frame 38,GO:0016021//integral component of membrane,-,-,-
255812,0,0,0,0,23,4,0,0,4,0,7,0,"SDHAP1;succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1",-,-,-,K00234//Metabolic pathways;Citrate cycle (TCA cycle);Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Biosynthesis of secondary metabolites
255877,95,0,0,0,0,0,24,0,55,0,0,0,"BCL6B;B-cell CLL/lymphoma 6, member B",GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding,K15618//Transcriptional misregulation in cancer
2559,51,0,0,0,17,0,0,0,16,0,0,159,"GABRA6;gamma-aminobutyric acid (GABA) A receptor, alpha 6",GO:0005887//integral component of plasma membrane;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0007165//signal transduction;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0006810//transport,GO:0004890//GABA-A receptor activity;GO:0008503//benzodiazepine receptor activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity,K05175//Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Nicotine addiction;Morphine addiction;GABAergic synapse
255919,0,0,0,0,0,0,18,0,0,0,0,0,CNEP1R1;CTD nuclear envelope phosphatase 1 regulatory subunit 1,GO:0005737//cytoplasm;GO:0071595//Nem1-Spo7 phosphatase complex;GO:0031965//nuclear membrane;GO:0016021//integral component of membrane,GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0034504//protein localization to nucleus;GO:0035307//positive regulation of protein dephosphorylation;GO:0006629//lipid metabolic process,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion
255928,0,0,0,0,0,28,42,0,36,0,0,0,SYT14;synaptotagmin XIV,GO:0016021//integral component of membrane,GO:0008219//cell death,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005543//phospholipid binding,K15290//Synaptic vesicle cycle
255967,0,42,0,11,52,21,23,0,0,0,0,0,PAN3;PAN3 poly(A) specific ribonuclease subunit,GO:0000932//cytoplasmic mRNA processing body;GO:0031251//PAN complex;GO:0005829//cytosol,"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006605//protein targeting;GO:0006468//protein phosphorylation;GO:0010467//gene expression;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0005524//ATP binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K12572//RNA degradation
256006,429,0,0,0,0,0,0,75,52,0,8,0,ANKRD31;ankyrin repeat domain 31,-,-,-,-
256051,0,8,0,14,36,15,0,62,13,73,3,0,ZNF549;zinc finger protein 549,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
256076,0,16,0,0,0,24,55,0,145,0,0,24,"COL6A5;collagen, type VI, alpha 5",GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005581//collagen trimer,GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion,GO:0005515//protein binding,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
2561,8,0,0,0,0,20,46,0,1,285,0,0,"GABRB2;gamma-aminobutyric acid (GABA) A receptor, beta 2",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,"GO:1902476//chloride transmembrane transport;GO:0043524//negative regulation of neuron apoptotic process;GO:0007605//sensory perception of sound;GO:0060119//inner ear receptor cell development;GO:0071420//cellular response to histamine;GO:0060384//innervation;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0051932//synaptic transmission, GABAergic;GO:0055085//transmembrane transport;GO:0090102//cochlea development",GO:0005254//chloride channel activity;GO:0005237//inhibitory extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity,K05181//Serotonergic synapse;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction;GABAergic synapse;Nicotine addiction;Morphine addiction
256126,0,107,0,10,31,0,18,0,8,0,38,0,SYCE2;synaptonemal complex central element protein 2,GO:0000801//central element,GO:0007130//synaptonemal complex assembly,-,-
256130,0,0,0,0,0,0,0,0,37,0,0,0,TMEM196;transmembrane protein 196,GO:0016021//integral component of membrane,-,-,-
256148,0,0,0,0,0,0,0,0,8,0,0,0,"OR4S1;olfactory receptor, family 4, subfamily S, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
256158,149,0,19,0,12,52,99,140,216,295,15,214,HMCN2;hemicentin 2,GO:0005578//proteinaceous extracellular matrix,GO:0050896//response to stimulus,GO:0005509//calcium ion binding,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
2562,78,0,0,7,42,0,60,0,30,0,12,0,"GABRB3;gamma-aminobutyric acid (GABA) A receptor, beta 3",GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:1902476//chloride transmembrane transport;GO:0007605//sensory perception of sound;GO:0043524//negative regulation of neuron apoptotic process;GO:0007165//signal transduction;GO:0060119//inner ear receptor cell development;GO:0034220//ion transmembrane transport;GO:0060384//innervation;GO:0071420//cellular response to histamine;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0060021//palate development;GO:0090102//cochlea development;GO:0055085//transmembrane transport,GO:0004890//GABA-A receptor activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity,K05181//GABAergic synapse;Nicotine addiction;Morphine addiction;Serotonergic synapse;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
256223,0,0,0,0,0,0,0,0,7,0,0,0,CDRT15L2;CMT1A duplicated region transcript 15-like 2,-,-,-,-
256227,0,0,0,0,0,0,0,0,20,0,12,0,STEAP1B;STEAP family member 1B,GO:0016021//integral component of membrane,-,-,K14737//Mineral absorption
256236,0,0,0,0,11,0,20,0,16,0,0,0,"NAPSB;napsin B aspartic peptidase, pseudogene",-,-,-,K08565//Lysosome
256281,74,0,0,0,1,0,0,0,21,0,0,0,NUDT14;nudix (nucleoside diphosphate linked moiety X)-type motif 14,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity;GO:0008768//UDP-sugar diphosphatase activity,K08077//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Nicotinate and nicotinamide metabolism;Metabolic pathways
256297,0,0,0,0,0,0,0,0,19,0,0,0,"PTF1A;pancreas specific transcription factor, 1a",GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0035881//amacrine cell differentiation;GO:0010842//retina layer formation;GO:0006351//transcription, DNA-templated;GO:0061074//regulation of neural retina development;GO:0031016//pancreas development;GO:0031018//endocrine pancreas development;GO:0031017//exocrine pancreas development;GO:0009790//embryo development;GO:0048663//neuron fate commitment;GO:0009888//tissue development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021549//cerebellum development;GO:0048384//retinoic acid receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0046983//protein dimerization activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0070888//E-box binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,-
2563,0,0,0,0,0,0,0,0,36,0,7,0,"GABRD;gamma-aminobutyric acid (GABA) A receptor, delta",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex,GO:0006810//transport;GO:1902476//chloride transmembrane transport;GO:0007165//signal transduction;GO:0007268//synaptic transmission,GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity,K05184//Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Nicotine addiction;Morphine addiction;GABAergic synapse
256302,32,1,0,0,0,0,0,0,14,0,0,0,NATD1;N-acetyltransferase domain containing 1,-,-,-,-
256309,0,0,0,8,0,0,0,0,40,0,0,0,CCDC110;coiled-coil domain containing 110,GO:0005634//nucleus,-,-,-
256329,0,0,14,0,41,17,0,1,7,0,57,363,LMNTD2;lamin tail domain containing 2,-,-,-,-
256356,0,46,0,50,240,0,41,0,40,0,0,0,GK5;glycerol kinase 5 (putative),-,GO:0016310//phosphorylation;GO:0019563//glycerol catabolic process,GO:0004370//glycerol kinase activity;GO:0005524//ATP binding,K00864//Glycerolipid metabolism;PPAR signaling pathway;Metabolic pathways;Plant-pathogen interaction
256364,0,0,0,0,0,0,0,0,17,117,0,0,EML3;echinoderm microtubule associated protein like 3,GO:0005874//microtubule;GO:0005737//cytoplasm,-,-,-
256369,0,0,0,0,8,0,0,0,91,0,0,0,LINC00521;long intergenic non-protein coding RNA 521,-,-,-,-
256380,0,0,0,0,0,25,35,55,54,0,0,0,SCML4;sex comb on midleg-like 4 (Drosophila),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
256394,74,0,0,0,0,0,19,0,27,21,0,0,"SERPINA11;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11",GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity,K03984//Complement and coagulation cascades
2564,0,0,0,0,0,30,0,0,20,0,13,0,"GABRE;gamma-aminobutyric acid (GABA) A receptor, epsilon",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane,GO:0007214//gamma-aminobutyric acid signaling pathway;GO:1902476//chloride transmembrane transport;GO:0006810//transport,GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity,K05185//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
256435,35,0,0,0,0,0,0,0,45,0,0,0,"ST6GALNAC3;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006687//glycosphingolipid metabolic process;GO:0097503//sialylation;GO:0006677//glycosylceramide metabolic process;GO:0006486//protein glycosylation;GO:0009100//glycoprotein metabolic process,GO:0008373//sialyltransferase activity,K03373//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
256471,2,12,1,0,0,9,34,0,53,0,0,0,MFSD8;major facilitator superfamily domain containing 8,GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0008219//cell death;GO:0055085//transmembrane transport,-,K12307//Lysosome
256472,85,0,0,0,0,0,0,0,20,0,0,0,TMEM151A;transmembrane protein 151A,GO:0016021//integral component of membrane,-,-,-
2565,0,0,0,0,0,0,22,0,23,0,3,0,"GABRG1;gamma-aminobutyric acid (GABA) A receptor, gamma 1",GO:0043235//receptor complex;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex,GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//synaptic transmission;GO:1902476//chloride transmembrane transport,GO:0004890//GABA-A receptor activity;GO:0050811//GABA receptor binding;GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity,K05186//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
256536,0,0,0,0,15,6,0,0,59,0,19,0,TCERG1L;transcription elongation regulator 1-like,-,-,-,K12824//Spliceosome
256586,0,0,0,0,0,29,0,0,6,0,0,0,"LYSMD2;LysM, putative peptidoglycan-binding, domain containing 2",-,-,-,-
2566,0,0,0,4,0,0,0,0,79,0,0,0,"GABRG2;gamma-aminobutyric acid (GABA) A receptor, gamma 2",GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0060077//inhibitory synapse;GO:0034707//chloride channel complex;GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0032590//dendrite membrane,"GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0051932//synaptic transmission, GABAergic;GO:0055085//transmembrane transport;GO:0071420//cellular response to histamine;GO:0030534//adult behavior;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0009791//post-embryonic development;GO:1902476//chloride transmembrane transport",GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0008503//benzodiazepine receptor activity;GO:0005515//protein binding;GO:0004890//GABA-A receptor activity,K05186//Morphine addiction;Nicotine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
256643,0,0,0,18,58,0,0,0,8,0,0,0,CXorf23;chromosome X open reading frame 23,GO:0005739//mitochondrion,-,-,K11447//Transcriptional misregulation in cancer
256646,0,0,0,0,0,26,46,2,28,69,0,0,"NUTM1;NUT midline carcinoma, family member 1",GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
2567,0,0,0,0,0,7,0,0,39,0,0,0,"GABRG3;gamma-aminobutyric acid (GABA) A receptor, gamma 3",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport,GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity,K05186//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
256710,0,0,0,2,0,0,0,0,20,0,0,0,GLIPR1L1;GLI pathogenesis-related 1 like 1,GO:0001669//acrosomal vesicle;GO:0005576//extracellular region;GO:0097224//sperm connecting piece,GO:0007339//binding of sperm to zona pellucida,-,-
256714,0,0,0,0,0,8,0,0,85,0,5,0,MAP7D2;MAP7 domain containing 2,GO:0005874//microtubule,GO:0000226//microtubule cytoskeleton organization,-,-
256764,0,0,0,0,0,7,7,49,12,0,0,0,WDR72;WD repeat domain 72,-,-,-,K03130//Herpes simplex infection;Basal transcription factors;K04508//Wnt signaling pathway;K12862//Spliceosome
2568,0,0,0,0,0,0,0,0,0,0,5,0,"GABRP;gamma-aminobutyric acid (GABA) A receptor, pi",GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:1902476//chloride transmembrane transport;GO:0007165//signal transduction,GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0004890//GABA-A receptor activity,K05189//GABAergic synapse;Morphine addiction;Nicotine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
256815,0,0,0,0,0,19,0,2,27,0,0,0,C10orf67;chromosome 10 open reading frame 67,-,-,-,-
2569,43,0,0,0,0,1,17,0,42,1,11,0,"GABRR1;gamma-aminobutyric acid (GABA) A receptor, rho 1",GO:0034707//chloride channel complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006810//transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway,GO:0004890//GABA-A receptor activity;GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity,K05190//Nicotine addiction;Morphine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
256933,0,0,11,11,98,0,0,98,18,0,88,0,NPB;neuropeptide B,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0001664//G-protein coupled receptor binding;GO:0005515//protein binding,-
256949,1,242,5,184,195,32,0,376,45,0,473,1,KANK3;KN motif and ankyrin repeat domains 3,-,-,-,-
256957,149,0,0,0,0,8,30,0,13,0,3,0,HEATR9;HEAT repeat containing 9,-,GO:0002244//hematopoietic progenitor cell differentiation,-,-
256979,0,0,0,0,0,0,0,0,14,0,0,0,SUN3;Sad1 and UNC84 domain containing 3,GO:0034993//SUN-KASH complex;GO:0016021//integral component of membrane,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
256987,0,1,1,29,61,0,0,0,18,0,0,0,SERINC5;serine incorporator 5,GO:0043209//myelin sheath;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0006658//phosphatidylserine metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0051347//positive regulation of transferase activity;GO:0015825//L-serine transport;GO:0006665//sphingolipid metabolic process;GO:0042552//myelination,GO:0015194//L-serine transmembrane transporter activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
257,0,80,1,70,62,0,0,273,91,0,193,3,ALX3;ALX homeobox 3,GO:0005634//nucleus,"GO:0048704//embryonic skeletal system morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0035116//embryonic hindlimb morphogenesis;GO:0007389//pattern specification process;GO:0006351//transcription, DNA-templated;GO:0035115//embryonic forelimb morphogenesis;GO:0042981//regulation of apoptotic process",GO:0043565//sequence-specific DNA binding,-
2570,0,0,0,0,0,21,19,0,16,0,0,0,"GABRR2;gamma-aminobutyric acid (GABA) A receptor, rho 2",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007268//synaptic transmission;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007165//signal transduction;GO:0007601//visual perception;GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0019904//protein domain specific binding;GO:0004890//GABA-A receptor activity,K05190//Morphine addiction;Nicotine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling
257000,0,0,0,0,0,0,0,0,14,0,0,0,TINCR;tissue differentiation-inducing non-protein coding RNA,-,-,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
257019,0,0,21,0,0,24,19,102,50,0,14,0,FRMD3;FERM domain containing 3,GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016021//integral component of membrane,-,GO:0008092//cytoskeletal protein binding,K06107//Tight junction
257044,0,0,0,0,0,21,0,0,30,0,13,0,C1orf101;chromosome 1 open reading frame 101,GO:0036128//CatSper complex,-,-,-
257062,0,0,0,0,0,13,0,0,38,0,3,0,CATSPERD;catsper channel auxiliary subunit delta,GO:0036128//CatSper complex;GO:0005886//plasma membrane;GO:0097228//sperm principal piece,GO:0032504//multicellular organism reproduction;GO:0048240//sperm capacitation;GO:0035036//sperm-egg recognition;GO:0007275//multicellular organismal development;GO:0030317//sperm motility;GO:0007338//single fertilization;GO:0007283//spermatogenesis,-,-
257068,73,0,0,0,0,0,4,0,17,0,0,0,"PLCXD2;phosphatidylinositol-specific phospholipase C, X domain containing 2",-,GO:0016042//lipid catabolic process;GO:0007165//signal transduction,GO:0004871//signal transducer activity;GO:0008081//phosphoric diester hydrolase activity,-
2571,126,0,0,0,0,11,9,0,34,0,0,1,"GAD1;glutamate decarboxylase 1 (brain, 67kDa)",GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0012506//vesicle membrane,GO:0018352//protein-pyridoxal-5-phosphate linkage;GO:0042493//response to drug;GO:0042136//neurotransmitter biosynthetic process;GO:0006538//glutamate catabolic process;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0006540//glutamate decarboxylation to succinate;GO:0009449//gamma-aminobutyric acid biosynthetic process,GO:0047485//protein N-terminus binding;GO:0030170//pyridoxal phosphate binding;GO:0004351//glutamate decarboxylase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0016595//glutamate binding,"K01580//Type I diabetes mellitus;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Butanoate metabolism;GABAergic synapse;Metabolic pathways;beta-Alanine metabolism;Alanine, aspartate and glutamate metabolism"
257101,46,0,36,0,0,0,0,0,7,0,0,193,ZNF683;zinc finger protein 683,GO:0005634//nucleus,"GO:0001779//natural killer cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
257106,0,20,0,12,42,18,28,140,15,0,49,2,ARHGAP30;Rho GTPase activating protein 30,GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K04573//Amyotrophic lateral sclerosis (ALS);K04450//Dopaminergic synapse;Cocaine addiction;HTLV-I infection;Alcoholism;Influenza A;MAPK signaling pathway;Amphetamine addiction;Epstein-Barr virus infection;K08773//Pathways in cancer;Pancreatic cancer;K08878//Pathways in cancer;Chronic myeloid leukemia
257144,0,0,0,0,10,0,28,0,67,0,0,0,"GCSAM;germinal center-associated, signaling and motility",GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0050855//regulation of B cell receptor signaling pathway;GO:2000402//negative regulation of lymphocyte migration,GO:0045159//myosin II binding;GO:0003779//actin binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,-
257160,0,0,0,0,22,14,0,0,9,0,3,0,RNF214;ring finger protein 214,-,-,GO:0008270//zinc ion binding,-
257169,0,0,0,0,0,0,0,0,1,0,11,0,C9orf43;chromosome 9 open reading frame 43,-,-,-,-
257177,0,357,233,617,1296,0,0,1,42,0,388,0,C1orf192;chromosome 1 open reading frame 192,-,-,-,-
257194,4,0,0,0,0,0,5,0,16,0,0,0,NEGR1;neuronal growth regulator 1,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0010976//positive regulation of neuron projection development;GO:0016337//single organismal cell-cell adhesion;GO:0007626//locomotory behavior;GO:0007631//feeding behavior,GO:0005515//protein binding,K06775//Cell adhesion molecules (CAMs)
2572,78,0,0,7,0,9,8,0,27,0,0,0,"GAD2;glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)",GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0030424//axon;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0031225//anchored component of membrane;GO:0000139//Golgi membrane;GO:0030672//synaptic vesicle membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0042136//neurotransmitter biosynthetic process;GO:0006540//glutamate decarboxylation to succinate;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0042493//response to drug,GO:0004351//glutamate decarboxylase activity;GO:0030170//pyridoxal phosphate binding;GO:0016595//glutamate binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,"K01580//beta-Alanine metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Type I diabetes mellitus;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Butanoate metabolism;GABAergic synapse"
257202,0,0,0,0,0,0,16,0,16,0,23,0,GPX6;glutathione peroxidase 6 (olfactory),GO:0005576//extracellular region,GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process,GO:0004602//glutathione peroxidase activity,K00432//Glutathione metabolism;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Huntington's disease;Two-component system;Arachidonic acid metabolism;Amyotrophic lateral sclerosis (ALS);Metabolic pathways
257203,0,0,0,0,0,4,0,0,15,0,0,289,DSCR9;Down syndrome critical region gene 9 (non-protein coding),-,-,-,-
257218,0,0,0,7,0,54,39,0,57,0,0,0,"SHPRH;SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase",GO:0000786//nucleosome;GO:0005634//nucleus,GO:0006334//nucleosome assembly;GO:0000209//protein polyubiquitination;GO:0006281//DNA repair,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0004386//helicase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005524//ATP binding,-
257236,0,0,0,0,0,29,0,3,17,0,10,0,CCDC96;coiled-coil domain containing 96,-,-,-,K10396//Dopaminergic synapse
257240,0,0,0,0,0,0,0,59,0,0,1,0,KLHL34;kelch-like family member 34,GO:0005615//extracellular space,-,-,-
257313,0,0,0,0,8,0,0,0,0,0,0,0,UTS2B;urotensin 2B,GO:0005576//extracellular region,GO:0008217//regulation of blood pressure;GO:0042312//regulation of vasodilation,GO:0005179//hormone activity;GO:0001664//G-protein coupled receptor binding,-
257364,82,0,0,10,0,11,0,0,12,1,0,0,SNX33;sorting nexin 33,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0005768//endosome;GO:0019898//extrinsic component of membrane,GO:0007032//endosome organization;GO:0045806//negative regulation of endocytosis;GO:0006886//intracellular protein transport;GO:0007067//mitotic nuclear division;GO:0000281//mitotic cytokinesis;GO:2000009//negative regulation of protein localization to cell surface;GO:0036089//cleavage furrow formation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0017038//protein import;GO:0016197//endosomal transport;GO:0097320//membrane tubulation;GO:0006897//endocytosis;GO:2000010//positive regulation of protein localization to cell surface;GO:0044351//macropinocytosis,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding,-
257397,0,77,0,62,170,0,0,1,35,162,0,0,TAB3;TGF-beta activated kinase 1/MAP3K7 binding protein 3,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade",GO:0005515//protein binding;GO:0008270//zinc ion binding,K12793//NOD-like receptor signaling pathway;NF-kappa B signaling pathway
2574,1,0,0,0,0,0,0,0,2,0,0,0,GAGE2C;G antigen 2C,-,-,-,-
257415,0,0,0,0,0,0,0,0,12,0,0,0,"FAM133B;family with sequence similarity 133, member B",-,-,GO:0044822//poly(A) RNA binding,-
25758,0,0,2,0,0,61,0,171,106,0,6,0,KIAA1549L;KIAA1549-like,GO:0016021//integral component of membrane,-,-,K10955//Amoebiasis;Vibrio cholerae infection;K13908//Salivary secretion
25759,0,0,0,3,12,0,0,31,4,0,12,0,SHC2;SHC (Src homology 2 domain containing) transforming protein 2,GO:0005829//cytosol,GO:0000187//activation of MAPK activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007265//Ras protein signal transduction,GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding,K06279//Focal adhesion;VEGF signaling pathway;Glioma;ErbB signaling pathway;Neurotrophin signaling pathway;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;Alcoholism;Insulin signaling pathway;Bacterial invasion of epithelial cells;Chemokine signaling pathway
257629,0,0,0,0,0,14,0,1,19,236,3,0,ANKS4B;ankyrin repeat and sterile alpha motif domain containing 4B,GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0034976//response to endoplasmic reticulum stress,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
25766,35,0,0,0,0,12,9,77,42,0,28,0,PRPF40B;PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae),GO:0016607//nuclear speck,GO:0006397//mRNA processing;GO:0008380//RNA splicing,-,K12821//Spliceosome
25769,0,0,0,0,0,23,0,0,43,0,0,0,"SLC24A2;solute carrier family 24 (sodium/potassium/calcium exchanger), member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031226//intrinsic component of plasma membrane,GO:0007601//visual perception;GO:0007613//memory;GO:0006874//cellular calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0007612//learning;GO:0060292//long term synaptic depression;GO:0035725//sodium ion transmembrane transport;GO:0060291//long-term synaptic potentiation;GO:0034220//ion transmembrane transport;GO:0006811//ion transport;GO:0006813//potassium ion transport,"GO:0030955//potassium ion binding;GO:0030145//manganese ion binding;GO:0046983//protein dimerization activity;GO:0031402//sodium ion binding;GO:0005509//calcium ion binding;GO:0016151//nickel cation binding;GO:0005262//calcium channel activity;GO:0008273//calcium, potassium:sodium antiporter activity;GO:0046870//cadmium ion binding;GO:0015293//symporter activity",-
25770,0,0,0,0,0,0,0,0,36,0,4,0,C22orf31;chromosome 22 open reading frame 31,-,-,-,-
25771,0,0,0,0,12,22,36,0,30,0,4,0,"TBC1D22A;TBC1 domain family, member 22A",-,GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity,GO:0042803//protein homodimerization activity;GO:0005097//Rab GTPase activator activity,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;K13136//RNA transport;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
25774,0,0,0,0,0,0,0,0,0,0,5,0,GSTTP1;glutathione S-transferase theta pseudogene 1,-,-,-,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
25775,0,0,0,0,0,0,0,0,8,0,0,0,C22orf24;chromosome 22 open reading frame 24,GO:0016021//integral component of membrane,-,-,-
25776,0,0,0,18,94,0,16,0,0,0,31,0,CBY1;chibby homolog 1 (Drosophila),GO:0016607//nuclear speck;GO:0036064//ciliary basal body;GO:0005802//trans-Golgi network;GO:0005634//nucleus,"GO:0030178//negative regulation of Wnt signaling pathway;GO:0008104//protein localization;GO:0042384//cilium assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0055007//cardiac muscle cell differentiation;GO:0045444//fat cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding,-
25777,0,0,0,17,9,0,12,154,0,0,8,0,SUN2;Sad1 and UNC84 domain containing 2,"GO:0016021//integral component of membrane;GO:0000784//nuclear chromosome, telomeric region;GO:0010008//endosome membrane;GO:0031965//nuclear membrane;GO:0000794//condensed nuclear chromosome;GO:0034993//SUN-KASH complex;GO:0005637//nuclear inner membrane;GO:0005635//nuclear envelope",GO:0090286//cytoskeletal anchoring at nuclear membrane;GO:0051642//centrosome localization;GO:0090292//nuclear matrix anchoring at nuclear membrane;GO:0031022//nuclear migration along microfilament;GO:0030335//positive regulation of cell migration;GO:0007052//mitotic spindle organization;GO:0007097//nuclear migration;GO:0006998//nuclear envelope organization,GO:0005521//lamin binding;GO:0042802//identical protein binding;GO:0008017//microtubule binding;GO:0005515//protein binding,-
25778,0,0,0,15,42,3,57,0,23,0,2,0,DSTYK;dual serine/threonine and tyrosine protein kinase,GO:0005737//cytoplasm,GO:0018108//peptidyl-tyrosine phosphorylation,GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity,-
25780,0,0,0,0,0,0,28,0,0,0,11,0,RASGRP3;RAS guanyl releasing protein 3 (calcium and DAG-regulated),GO:0005886//plasma membrane;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0000165//MAPK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0032854//positive regulation of Rap GTPase activity;GO:0043547//positive regulation of GTPase activity,GO:0005509//calcium ion binding;GO:0019992//diacylglycerol binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding;GO:0019900//kinase binding;GO:0004871//signal transducer activity;GO:0046582//Rap GTPase activator activity;GO:0005088//Ras guanyl-nucleotide exchange factor activity,K12362//MAPK signaling pathway;B cell receptor signaling pathway
25782,115,1,0,21,24,24,30,1,52,0,3,0,RAB3GAP2;RAB3 GTPase activating protein subunit 2 (non-catalytic),GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0005886//plasma membrane,GO:0043547//positive regulation of GTPase activity;GO:0097051//establishment of protein localization to endoplasmic reticulum membrane;GO:0032851//positive regulation of Rab GTPase activity;GO:0006886//intracellular protein transport;GO:0043087//regulation of GTPase activity;GO:0043085//positive regulation of catalytic activity,GO:0046982//protein heterodimerization activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity;GO:0030234//enzyme regulator activity;GO:0008047//enzyme activator activity;GO:0017137//Rab GTPase binding,-
25788,26,0,0,0,16,0,2,0,44,0,4,0,RAD54B;RAD54 homolog B (S. cerevisiae),GO:0005634//nucleus,GO:0006312//mitotic recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006200//ATP catabolic process;GO:0032508//DNA duplex unwinding;GO:0007131//reciprocal meiotic recombination,GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0003677//DNA binding;GO:0015616//DNA translocase activity;GO:0003724//RNA helicase activity,K10877//Homologous recombination
25789,0,0,0,0,0,12,29,0,2,0,0,0,TMEM59L;transmembrane protein 59-like,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,-,-,-
25790,2,0,0,0,0,0,33,83,39,0,0,0,CCDC19;coiled-coil domain containing 19,GO:0005634//nucleus;GO:0005739//mitochondrion,-,-,K05702//Tight junction;Leukocyte transendothelial migration;Adherens junction
25791,74,0,1,0,0,0,0,5,72,0,0,0,NGEF;neuronal guanine nucleotide exchange factor,GO:0016020//membrane;GO:0005829//cytosol;GO:0030426//growth cone,GO:0048013//ephrin receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0043087//regulation of GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K07525//Axon guidance
25792,0,0,0,0,7,0,40,99,20,77,5,0,CIZ1;CDKN1A interacting zinc finger protein 1,GO:0005634//nucleus,GO:0051457//maintenance of protein location in nucleus;GO:0032298//positive regulation of DNA-dependent DNA replication initiation,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding;GO:0030332//cyclin binding;GO:0005515//protein binding,-
25793,0,28,0,18,79,0,16,0,0,0,3,85,FBXO7;F-box protein 7,GO:0005634//nucleus;GO:0043234//protein complex;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0016567//protein ubiquitination;GO:0031647//regulation of protein stability;GO:0000422//mitochondrion degradation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006626//protein targeting to mitochondrion;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008219//cell death,GO:0019901//protein kinase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
25794,0,0,0,0,1,0,0,0,0,0,5,0,"FSCN2;fascin actin-bundling protein 2, retinal",GO:0005737//cytoplasm;GO:0032420//stereocilium;GO:0015629//actin cytoskeleton,GO:0051017//actin filament bundle assembly;GO:0042462//eye photoreceptor cell development;GO:0007601//visual perception;GO:0030036//actin cytoskeleton organization;GO:0009653//anatomical structure morphogenesis,"GO:0003779//actin binding;GO:0030674//protein binding, bridging;GO:0051015//actin filament binding",-
25796,0,0,0,13,2,0,39,0,0,0,0,0,PGLS;6-phosphogluconolactonase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0006098//pentose-phosphate shunt;GO:0005975//carbohydrate metabolic process;GO:0009051//pentose-phosphate shunt, oxidative branch",GO:0017057//6-phosphogluconolactonase activity;GO:0048029//monosaccharide binding,K01057//Phosphotransferase system (PTS);Biosynthesis of secondary metabolites;Glutathione metabolism;Ascorbate and aldarate metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways
25797,0,0,0,0,0,32,0,0,10,0,0,0,QPCT;glutaminyl-peptide cyclotransferase,GO:0070062//extracellular vesicular exosome,"GO:0006464//cellular protein modification process;GO:0017186//peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase",GO:0016603//glutaminyl-peptide cyclotransferase activity;GO:0008270//zinc ion binding,-
25798,0,113,75,264,296,0,57,141,76,1,435,0,BRI3;brain protein I3,GO:0016021//integral component of membrane,-,-,"K09699//Valine, leucine and isoleucine degradation;Metabolic pathways;Biosynthesis of secondary metabolites"
25799,0,0,0,21,18,0,0,0,32,0,11,3,ZNF324;zinc finger protein 324,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
258,0,0,0,0,0,0,1,0,0,117,1,0,AMBN;ameloblastin (enamel matrix protein),GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion;GO:0031214//biomineral tissue development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0008283//cell proliferation,GO:0008083//growth factor activity;GO:0030345//structural constituent of tooth enamel,-
2580,0,0,1,0,15,17,21,0,9,0,2,0,GAK;cyclin G associated kinase,GO:0048471//perinuclear region of cytoplasm;GO:0005925//focal adhesion;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane,GO:0007049//cell cycle;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0048853//forebrain morphogenesis;GO:0048468//cell development;GO:0007029//endoplasmic reticulum organization;GO:0009913//epidermal cell differentiation;GO:0061436//establishment of skin barrier;GO:0072583//clathrin-mediated endocytosis;GO:0007030//Golgi organization;GO:0006468//protein phosphorylation;GO:0072318//clathrin coat disassembly;GO:0035622//intrahepatic bile duct development,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
25800,0,9,0,10,120,1,0,0,40,0,0,0,"SLC39A6;solute carrier family 39 (zinc transporter), member 6",GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0031258//lamellipodium membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0071577//zinc ion transmembrane transport;GO:0071578//zinc ion transmembrane import;GO:0006882//cellular zinc ion homeostasis;GO:0055085//transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity,-
25801,46,1,0,4,1,0,0,0,11,187,0,562,"GCA;grancalcin, EF-hand calcium binding protein",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0061025//membrane fusion;GO:0006508//proteolysis,GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,-
258010,0,0,0,15,22,0,0,0,24,0,0,0,SVIP;small VCP/p97-interacting protein,GO:0030868//smooth endoplasmic reticulum membrane;GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0000139//Golgi membrane,GO:0010508//positive regulation of autophagy;GO:1903070//negative regulation of ER-associated ubiquitin-dependent protein catabolic process;GO:1903061//positive regulation of protein lipidation;GO:0031333//negative regulation of protein complex assembly,GO:0043621//protein self-association,K14014//Protein processing in endoplasmic reticulum
25802,0,0,0,23,0,45,0,0,31,0,23,0,LMOD1;leiomodin 1 (smooth muscle),GO:0016020//membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton,GO:0006936//muscle contraction,GO:0005523//tropomyosin binding;GO:0003779//actin binding,-
25803,40,2,1,22,42,0,0,15,1,0,0,0,SPDEF;SAM pointed domain containing ETS transcription factor,GO:0005634//nucleus,GO:0060480//lung goblet cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0010455//positive regulation of cell fate commitment;GO:0010454//negative regulation of cell fate commitment;GO:0060576//intestinal epithelial cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding,-
25804,98,1,0,0,44,0,19,1,0,0,2,0,"LSM4;LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005688//U6 snRNP;GO:0005681//spliceosomal complex;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex,"GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12623//Spliceosome;RNA degradation
25807,0,0,0,3,0,0,0,44,12,0,0,234,RHBDD3;rhomboid domain containing 3,GO:0016021//integral component of membrane,GO:0001889//liver development;GO:0045732//positive regulation of protein catabolic process;GO:0050708//regulation of protein secretion;GO:0006508//proteolysis;GO:0000165//MAPK cascade;GO:0009410//response to xenobiotic stimulus,GO:0004252//serine-type endopeptidase activity,-
25809,0,0,0,0,13,0,0,0,10,0,0,0,"TTLL1;tubulin tyrosine ligase-like family, member 1",GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0018095//protein polyglutamylation;GO:0035082//axoneme assembly;GO:0003351//epithelial cilium movement,GO:0070740//tubulin-glutamic acid ligase activity,"K05755//Fc gamma R-mediated phagocytosis;Pathogenic Escherichia coli infection;Shigellosis;Salmonella infection;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;K00273//Metabolic pathways;Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism;Peroxisome;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism"
2581,1,31,78,0,12,41,0,139,24,0,0,465,GALC;galactosylceramidase,GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0043202//lysosomal lumen,GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006683//galactosylceramide catabolic process;GO:0006665//sphingolipid metabolic process;GO:0005975//carbohydrate metabolic process,GO:0004336//galactosylceramidase activity,K01202//Metabolic pathways;Sphingolipid metabolism;Lysosome
25812,0,0,8,0,0,1,7,0,1,1,1,0,"POM121L1P;POM121 transmembrane nucleoporin-like 1, pseudogene",-,-,-,K14316//RNA transport
25813,0,0,0,2,4,19,0,0,25,0,0,0,SAMM50;SAMM50 sorting and assembly machinery component,GO:0001401//mitochondrial sorting and assembly machinery complex;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0045040//protein import into mitochondrial outer membrane;GO:0006626//protein targeting to mitochondrion,GO:0005515//protein binding,-
25814,0,29,84,36,58,0,0,138,32,0,0,0,ATXN10;ataxin 10,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0031175//neuron projection development;GO:0007399//nervous system development,GO:0042802//identical protein binding;GO:0005515//protein binding,-
25816,0,0,0,1,66,35,25,0,47,0,0,0,"TNFAIP8;tumor necrosis factor, alpha-induced protein 8",GO:0005737//cytoplasm,GO:0043066//negative regulation of apoptotic process;GO:0032611//interleukin-1 beta production;GO:0050830//defense response to Gram-positive bacterium;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process,K06264//ECM-receptor interaction
25817,114,0,0,0,0,18,0,0,4,0,0,0,"FAM19A5;family with sequence similarity 19 (chemokine (C-C motif)-like), member A5",GO:0005576//extracellular region;GO:0016021//integral component of membrane,-,-,-
25818,0,0,1,0,0,0,46,1,13,0,0,0,KLK5;kallikrein-related peptidase 5,GO:0097209//epidermal lamellar body;GO:0005615//extracellular space,GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0006508//proteolysis;GO:0008544//epidermis development,GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity,-
25819,0,0,0,0,0,13,0,0,0,107,0,0,CCRN4L;CCR4 carbon catabolite repression 4-like (S. cerevisiae),GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0010629//negative regulation of gene expression;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0048255//mRNA stabilization;GO:0009991//response to extracellular stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0045600//positive regulation of fat cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0032922//circadian regulation of gene expression;GO:0045995//regulation of embryonic development;GO:0042752//regulation of circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006397//mRNA processing;GO:0033962//cytoplasmic mRNA processing body assembly",GO:0003729//mRNA binding;GO:0004535//poly(A)-specific ribonuclease activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,K12603//RNA degradation
2582,0,1,1,11,6,0,9,0,16,0,0,0,GALE;UDP-galactose-4-epimerase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019388//galactose catabolic process,GO:0042803//protein homodimerization activity;GO:0003978//UDP-glucose 4-epimerase activity;GO:0050662//coenzyme binding,K01784//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Galactose metabolism;Metabolic pathways
25820,0,0,0,0,28,0,30,0,0,0,0,0,ARIH1;ariadne RBR E3 ubiquitin protein ligase 1,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,GO:0019221//cytokine-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0019787//small conjugating protein ligase activity,-
25821,0,0,0,15,29,32,35,0,10,0,0,0,MTO1;mitochondrial tRNA translation optimization 1,GO:0005739//mitochondrion,GO:0070899//mitochondrial tRNA wobble uridine modification;GO:0055114//oxidation-reduction process,GO:0050660//flavin adenine dinucleotide binding;GO:0044822//poly(A) RNA binding,-
25822,100,0,0,0,0,0,16,1,27,0,3,0,"DNAJB5;DnaJ (Hsp40) homolog, subfamily B, member 5",GO:0005829//cytosol;GO:0005634//nucleus,GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0051087//chaperone binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,-
25823,0,0,0,0,0,1,0,13,3,0,0,0,TPSG1;tryptase gamma 1,GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
25824,0,43,0,0,7,2,0,0,7,0,0,0,PRDX5;peroxiredoxin 5,GO:0005782//peroxisomal matrix;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005777//peroxisome;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome,GO:0060785//regulation of apoptosis involved in tissue homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0006979//response to oxidative stress;GO:2001057//reactive nitrogen species metabolic process;GO:0055114//oxidation-reduction process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0070995//NADPH oxidation;GO:0034614//cellular response to reactive oxygen species;GO:0051354//negative regulation of oxidoreductase activity;GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0042744//hydrogen peroxide catabolic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006954//inflammatory response,GO:0016209//antioxidant activity;GO:0051920//peroxiredoxin activity;GO:0046983//protein dimerization activity;GO:0004601//peroxidase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0072541//peroxynitrite reductase activity;GO:0001016//RNA polymerase III regulatory region DNA binding;GO:0005102//receptor binding,K11187//Peroxisome
25825,0,0,0,2,8,0,25,0,40,0,0,0,BACE2;beta-site APP-cleaving enzyme 2,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005768//endosome;GO:0005794//Golgi apparatus,GO:0006508//proteolysis;GO:0006509//membrane protein ectodomain proteolysis;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0016486//peptide hormone processing,GO:0004190//aspartic-type endopeptidase activity,K07747//Alzheimer's disease
25827,0,0,0,0,0,0,2,0,1,0,14,0,FBXL2;F-box and leucine-rich repeat protein 2,GO:0005737//cytoplasm;GO:0016020//membrane,GO:0006513//protein monoubiquitination;GO:0006508//proteolysis;GO:0016032//viral process;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0005516//calmodulin binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
25828,3,25,0,6,21,0,0,0,0,0,8,0,TXN2;thioredoxin 2,GO:0043025//neuronal cell body;GO:0005759//mitochondrial matrix;GO:0005730//nucleolus;GO:0030425//dendrite;GO:0005739//mitochondrion,GO:0006979//response to oxidative stress;GO:0045454//cell redox homeostasis;GO:0048678//response to axon injury;GO:0001666//response to hypoxia;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0031669//cellular response to nutrient levels;GO:0009725//response to hormone;GO:0009749//response to glucose;GO:0014070//response to organic cyclic compound;GO:0042493//response to drug;GO:0006662//glycerol ether metabolic process,GO:0032403//protein complex binding;GO:0015035//protein disulfide oxidoreductase activity,K03671//Pyrimidine metabolism;Selenocompound metabolism
25829,69,0,0,0,0,11,0,60,8,0,9,0,TMEM184B;transmembrane protein 184B,GO:0016021//integral component of membrane,-,-,K14360//Bile secretion
2583,0,0,0,0,0,25,0,0,25,0,2,0,"B4GALNT1;beta-1,4-N-acetyl-galactosaminyl transferase 1",GO:0030173//integral component of Golgi membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0005975//carbohydrate metabolic process;GO:0008219//cell death;GO:0006486//protein glycosylation;GO:0007283//spermatogenesis;GO:0006687//glycosphingolipid metabolic process;GO:0001574//ganglioside biosynthetic process;GO:0019915//lipid storage;GO:0030259//lipid glycosylation,GO:0003947//(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity,K00725//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
25830,0,1,70,0,0,0,0,0,5,0,3,215,"SULT4A1;sulfotransferase family 4A, member 1",GO:0005829//cytosol,GO:0008202//steroid metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0006805//xenobiotic metabolic process,GO:0008146//sulfotransferase activity;GO:0005515//protein binding,-
25831,177,40,0,49,253,18,22,39,100,333,0,0,HECTD1;HECT domain containing E3 ubiquitin protein ligase 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0001843//neural tube closure,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
25833,19,0,42,0,0,20,55,0,9,28,0,623,POU2F3;POU class 2 homeobox 3,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043922//negative regulation by host of viral transcription;GO:0042060//wound healing;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046983//protein dimerization activity,K09364//Herpes simplex infection
25834,0,0,0,0,0,0,0,0,18,79,0,188,"MGAT4C;mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification,"GO:0008454//alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding",K13748//N-Glycan biosynthesis;Metabolic pathways
25836,193,0,42,23,281,12,36,1,126,38,11,0,NIPBL;Nipped-B homolog (Drosophila),GO:0032116//SMC loading complex;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0031065//positive regulation of histone deacetylation;GO:0042634//regulation of hair cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0045444//fat cell differentiation;GO:0000278//mitotic cell cycle;GO:0045778//positive regulation of ossification;GO:0045995//regulation of embryonic development;GO:0034613//cellular protein localization;GO:0007064//mitotic sister chromatid cohesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048557//embryonic digestive tract morphogenesis;GO:0001656//metanephros development;GO:0007605//sensory perception of sound;GO:0061010//gall bladder development;GO:0071481//cellular response to X-ray;GO:0035261//external genitalia morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060325//face morphogenesis;GO:0061038//uterus morphogenesis;GO:0048589//developmental growth;GO:0048592//eye morphogenesis;GO:0003007//heart morphogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0003151//outflow tract morphogenesis;GO:0042471//ear morphogenesis;GO:0019827//stem cell maintenance;GO:0035115//embryonic forelimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0050890//cognition;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0007420//brain development;GO:0048638//regulation of developmental growth;GO:0048703//embryonic viscerocranium morphogenesis",GO:0070087//chromo shadow domain binding;GO:0003682//chromatin binding;GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0036033//mediator complex binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding,K06672//Cell cycle - yeast
25837,0,0,0,0,0,0,0,0,0,0,6,0,"RAB26;RAB26, member RAS oncogene family",GO:0030658//transport vesicle membrane;GO:0031226//intrinsic component of plasma membrane;GO:0000139//Golgi membrane;GO:0030667//secretory granule membrane,GO:0007264//small GTPase mediated signal transduction;GO:0017157//regulation of exocytosis;GO:0043001//Golgi to plasma membrane protein transport;GO:0045055//regulated secretory pathway;GO:0035272//exocrine system development,GO:0019002//GMP binding;GO:0005515//protein binding;GO:0005525//GTP binding,-
25839,0,34,0,7,9,0,21,6,42,0,0,0,COG4;component of oligomeric golgi complex 4,GO:0017119//Golgi transport complex;GO:0000139//Golgi membrane,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0015031//protein transport;GO:0007030//Golgi organization;GO:0048213//Golgi vesicle prefusion complex stabilization",GO:0005515//protein binding,-
25840,50,27,1,0,19,0,0,7,4,0,0,0,METTL7A;methyltransferase like 7A,GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0032259//methylation,GO:0008168//methyltransferase activity,K11447//Transcriptional misregulation in cancer
25841,123,14,0,0,16,8,12,52,16,0,8,0,ABTB2;ankyrin repeat and BTB (POZ) domain containing 2,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0097237//cellular response to toxic substance,GO:0046982//protein heterodimerization activity,-
25842,0,0,161,24,73,32,0,0,42,0,67,0,ASF1A;anti-silencing function 1A histone chaperone,GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006334//nucleosome assembly;GO:0001649//osteoblast differentiation;GO:0031936//negative regulation of chromatin silencing;GO:0006281//DNA repair;GO:0042692//muscle cell differentiation;GO:0016568//chromatin modification;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0042393//histone binding;GO:0005515//protein binding,-
25843,0,0,0,5,8,0,0,0,0,0,0,0,"MOB4;MOB family member 4, phocein",GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0032580//Golgi cisterna membrane,GO:0006810//transport,GO:0019900//kinase binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
25844,81,0,11,0,17,0,0,0,17,98,0,1,"YIPF3;Yip1 domain family, member 3",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0030133//transport vesicle,GO:0030154//cell differentiation,-,-
25847,0,109,27,63,130,20,0,0,24,0,6,0,ANAPC13;anaphase promoting complex subunit 13,GO:0005680//anaphase-promoting complex,GO:0070979//protein K11-linked ubiquitination;GO:0007067//mitotic nuclear division,-,K12456//Oocyte meiosis;Cell cycle;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation
25849,0,0,0,6,42,0,7,0,30,0,0,0,PARM1;prostate androgen-regulated mucin-like protein 1,GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005770//late endosome,GO:0051973//positive regulation of telomerase activity,-,-
2585,0,0,1,16,13,0,17,0,11,0,21,0,GALK2;galactokinase 2,GO:0005737//cytoplasm,GO:0005975//carbohydrate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0006012//galactose metabolic process,GO:0033858//N-acetylgalactosamine kinase activity;GO:0004335//galactokinase activity;GO:0005524//ATP binding,K00849//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Citrate cycle (TCA cycle);Metabolic pathways;Microbial metabolism in diverse environments;Galactose metabolism
25850,24,0,0,9,8,19,0,0,51,0,0,0,ZNF345;zinc finger protein 345,GO:0005634//nucleus,"GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
25851,43,29,0,14,18,35,114,1,19,25,20,580,TECPR1;tectonin beta-propeller repeat containing 1,GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle;GO:0000421//autophagic vacuole membrane;GO:0005765//lysosomal membrane,GO:0000046//autophagic vacuole fusion;GO:0006914//autophagy,GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
25852,0,8,0,5,53,43,30,0,19,1,0,0,ARMC8;armadillo repeat containing 8,-,-,-,K02105//Tight junction;Bacterial invasion of epithelial cells;HTLV-I infection;Leukocyte transendothelial migration;Endometrial cancer;Pathogenic Escherichia coli infection;Focal adhesion;Thyroid cancer;Melanogenesis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Basal cell carcinoma;Prostate cancer;Wnt signaling pathway;Adherens junction;Colorectal cancer;K06059//Alzheimer's disease;Epithelial cell signaling in Helicobacter pylori infection;Notch signaling pathway
25853,4,24,56,36,56,0,0,118,15,0,0,0,DCAF12;DDB1 and CUL4 associated factor 12,GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,-,-
25854,0,0,0,0,39,17,21,3,19,0,1,0,"FAM149A;family with sequence similarity 149, member A",-,-,-,-
25855,68,0,0,6,1,0,0,0,16,0,0,0,BRMS1;breast cancer metastasis suppressor 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:2000210//positive regulation of anoikis;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0090312//positive regulation of protein deacetylation",GO:0051059//NF-kappaB binding;GO:0005515//protein binding,-
25858,75,0,0,0,0,25,0,0,0,0,0,0,TEX40;testis expressed 40,GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007140//male meiosis,-,-
25861,0,0,0,0,13,1,5,76,42,189,9,0,"DFNB31;deafness, autosomal recessive 31",GO:0002142//stereocilia ankle link complex;GO:0005929//cilium;GO:0005884//actin filament;GO:0032420//stereocilium;GO:0030426//growth cone;GO:0005737//cytoplasm,GO:0050953//sensory perception of light stimulus;GO:0001895//retina homeostasis;GO:0007605//sensory perception of sound;GO:0060122//inner ear receptor stereocilium organization,GO:0005515//protein binding,K12076//HTLV-I infection;T cell receptor signaling pathway;K11828//Huntington's disease;Glutamatergic synapse;Cocaine addiction
25862,0,0,0,0,21,31,39,0,40,0,1,0,USP49;ubiquitin specific peptidase 49,GO:0005634//nucleus,"GO:0016579//protein deubiquitination;GO:0035616//histone H2B conserved C-terminal lysine deubiquitination;GO:0000398//mRNA splicing, via spliceosome;GO:0006511//ubiquitin-dependent protein catabolic process",GO:0004843//ubiquitin-specific protease activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0004221//ubiquitin thiolesterase activity,-
25864,0,0,0,0,3,0,0,0,0,0,0,0,ABHD14A;abhydrolase domain containing 14A,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K14677//Metabolic pathways;Biosynthesis of secondary metabolites;Arginine and proline metabolism
25865,0,0,0,6,21,0,0,128,8,0,7,0,PRKD2;protein kinase D2,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0001525//angiogenesis;GO:0061154//endothelial tube morphogenesis;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:1901727//positive regulation of histone deacetylase activity;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0007155//cell adhesion;GO:0032793//positive regulation of CREB transcription factor activity;GO:0032743//positive regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0008219//cell death;GO:0045766//positive regulation of angiogenesis;GO:2000573//positive regulation of DNA biosynthetic process;GO:0001938//positive regulation of endothelial cell proliferation;GO:0046777//protein autophosphorylation;GO:0045785//positive regulation of cell adhesion;GO:0018105//peptidyl-serine phosphorylation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:1902533//positive regulation of intracellular signal transduction;GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004697//protein kinase C activity,-
2587,0,0,0,0,0,9,32,0,9,0,0,0,GALR1;galanin receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007586//digestion;GO:0051464//positive regulation of cortisol secretion;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity,GO:0017046//peptide hormone binding;GO:0004966//galanin receptor activity;GO:0042923//neuropeptide binding;GO:0005515//protein binding,K04230//Neuroactive ligand-receptor interaction
25870,159,18,0,16,10,10,0,82,42,0,11,0,SUMF2;sulfatase modifying factor 2,GO:0005788//endoplasmic reticulum lumen,GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0046872//metal ion binding,K13444//Lysosome
25871,97,231,214,402,329,22,0,2,12,0,386,0,C3orf17;chromosome 3 open reading frame 17,GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0045665//negative regulation of neuron differentiation;GO:0045747//positive regulation of Notch signaling pathway,-,-
25873,57,25,0,0,4,0,0,0,0,0,0,4,RPL36;ribosomal protein L36,GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0005730//nucleolus,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016032//viral process;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,K02920//Ribosome
25874,0,236,137,293,686,0,11,236,68,139,974,289,MPC2;mitochondrial pyruvate carrier 2,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:1901475//pyruvate transmembrane transport;GO:0006090//pyruvate metabolic process;GO:0044237//cellular metabolic process;GO:0006850//mitochondrial pyruvate transport;GO:0044281//small molecule metabolic process,GO:0050833//pyruvate transmembrane transporter activity,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
25875,0,0,0,0,0,0,0,0,11,0,0,0,LETMD1;LETM1 domain containing 1,GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane,-,GO:0005515//protein binding,-
25876,68,0,0,0,2,0,0,0,2,0,0,0,SPEF1;sperm flagellar 1,GO:0031514//motile cilium;GO:0005856//cytoskeleton;GO:0005930//axoneme,-,-,-
25878,0,0,0,0,0,0,59,0,49,0,1,203,MXRA5;matrix-remodelling associated 5,GO:0070062//extracellular vesicular exosome,-,-,K06255//ECM-receptor interaction
25879,0,149,0,86,122,29,3,41,36,0,71,0,DCAF13;DDB1 and CUL4 associated factor 13,GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,GO:0016567//protein ubiquitination;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
2588,0,0,0,0,0,0,0,2,13,0,0,0,GALNS;galactosamine (N-acetyl)-6-sulfatase,GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen,GO:0005975//carbohydrate metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0008484//sulfuric ester hydrolase activity;GO:0043890//N-acetylgalactosamine-6-sulfatase activity;GO:0046872//metal ion binding;GO:0003943//N-acetylgalactosamine-4-sulfatase activity,K01132//Lysosome;Metabolic pathways;Glycosaminoglycan degradation
25880,0,0,0,9,0,0,19,53,0,0,0,0,TMEM186;transmembrane protein 186,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,-
25884,0,0,0,0,0,0,30,70,23,0,8,1,CHRDL2;chordin-like 2,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0051216//cartilage development;GO:0001503//ossification;GO:0030154//cell differentiation,-,K04657//TGF-beta signaling pathway
25885,0,0,0,1,28,20,47,30,59,0,27,0,"POLR1A;polymerase (RNA) I polypeptide A, 194kDa",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005730//nucleolus,GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0010467//gene expression;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter,GO:0001054//RNA polymerase I activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,K02999//Pyrimidine metabolism;RNA polymerase;Purine metabolism;Metabolic pathways
25886,0,0,0,0,0,0,0,37,11,95,9,0,POC1A;POC1 centriolar protein A,GO:0005813//centrosome;GO:0000922//spindle pole;GO:0036064//ciliary basal body;GO:0005814//centriole,GO:0030030//cell projection organization,GO:0005515//protein binding,K01062//Biosynthesis of secondary metabolites;Ether lipid metabolism;Metabolic pathways;K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
25888,60,1,1,28,13,20,0,59,0,134,12,0,ZNF473;zinc finger protein 473,GO:0015030//Cajal body;GO:0005654//nucleoplasm,"GO:0006398//histone mRNA 3'-end processing;GO:0006355//regulation of transcription, DNA-templated;GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
2589,0,1,0,28,39,15,3,0,62,0,0,0,GALNT1;polypeptide N-acetylgalactosaminyltransferase 1,GO:0048471//perinuclear region of cytoplasm;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus,GO:0006493//protein O-linked glycosylation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0018243//protein O-linked glycosylation via threonine;GO:0018242//protein O-linked glycosylation via serine,GO:0030246//carbohydrate binding;GO:0030145//manganese ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
25890,43,0,0,8,0,20,0,23,74,0,7,0,"ABI3BP;ABI family, member 3 (NESH) binding protein",GO:0031012//extracellular matrix;GO:0005614//interstitial matrix;GO:0005615//extracellular space,GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization,GO:0005518//collagen binding;GO:0008201//heparin binding,K13909//Salivary secretion;K06759//Cell adhesion molecules (CAMs);K10955//Vibrio cholerae infection;Amoebiasis;K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
25891,0,0,0,0,0,0,19,0,18,0,31,0,PAMR1;peptidase domain containing associated with muscle regeneration 1,GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0003824//catalytic activity,K03992//Staphylococcus aureus infection;Complement and coagulation cascades
25893,0,0,0,0,0,0,42,0,1,0,13,0,TRIM58;tripartite motif containing 58,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
25894,21,1,0,0,16,45,75,89,32,0,13,0,"PLEKHG4;pleckstrin homology domain containing, family G (with RhoGef domain) member 4",-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
25895,0,0,0,13,1,18,0,0,0,1,5,0,METTL21B;methyltransferase like 21B,GO:0005622//intracellular;GO:0005737//cytoplasm,GO:0032259//methylation,GO:0008168//methyltransferase activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
25896,0,0,0,1,20,10,0,0,42,0,0,0,INTS7;integrator complex subunit 7,GO:0032039//integrator complex;GO:0005694//chromosome,GO:0016180//snRNA processing;GO:0071479//cellular response to ionizing radiation;GO:0000077//DNA damage checkpoint,GO:0005515//protein binding,-
25897,0,0,0,4,45,0,0,0,20,0,18,0,"RNF19A;ring finger protein 19A, RBR E3 ubiquitin protein ligase",GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0000226//microtubule cytoskeleton organization;GO:0016567//protein ubiquitination,GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
25898,0,0,1,23,38,3,0,0,22,0,0,0,"RCHY1;ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase",GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051865//protein autoubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031398//positive regulation of protein ubiquitination,GO:0008270//zinc ion binding;GO:0002039//p53 binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding,K10144//Ubiquitin mediated proteolysis;p53 signaling pathway;Measles
259,0,0,0,4,25,0,0,115,26,0,0,0,AMBP;alpha-1-microglobulin/bikunin precursor,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle,GO:0010951//negative regulation of endopeptidase activity;GO:0018298//protein-chromophore linkage;GO:0042167//heme catabolic process;GO:0046329//negative regulation of JNK cascade;GO:0007155//cell adhesion;GO:0007565//female pregnancy;GO:0016032//viral process;GO:0030163//protein catabolic process;GO:0050777//negative regulation of immune response,GO:0036094//small molecule binding;GO:0020037//heme binding;GO:0019862//IgA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019855//calcium channel inhibitor activity;GO:0046904//calcium oxalate binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K03909//Complement and coagulation cascades
2590,117,0,0,0,0,38,44,0,23,0,0,0,GALNT2;polypeptide N-acetylgalactosaminyltransferase 2,GO:0030173//integral component of Golgi membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005795//Golgi stack;GO:0032580//Golgi cisterna membrane,GO:0044267//cellular protein metabolic process;GO:0006493//protein O-linked glycosylation;GO:0002378//immunoglobulin biosynthetic process;GO:0018243//protein O-linked glycosylation via threonine;GO:0018242//protein O-linked glycosylation via serine;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0030145//manganese ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
25900,0,0,0,0,0,12,10,0,0,0,0,0,IFFO1;intermediate filament family orphan 1,GO:0005882//intermediate filament,-,-,"K07610//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;K00294//Arginine and proline metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism"
25901,0,2,2,43,65,0,0,0,20,0,0,0,CCDC28A;coiled-coil domain containing 28A,-,-,-,-
25902,0,0,0,16,0,9,21,0,19,2,16,0,MTHFD1L;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0035999//tetrahydrofolate interconversion;GO:0006760//folic acid-containing compound metabolic process;GO:0046653//tetrahydrofolate metabolic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0055114//oxidation-reduction process;GO:0015942//formate metabolic process;GO:0006730//one-carbon metabolic process,GO:0042803//protein homodimerization activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0005524//ATP binding,K13402//One carbon pool by folate;Metabolic pathways
25904,0,10,0,0,0,12,70,0,45,0,0,0,"CNOT10;CCR4-NOT transcription complex, subunit 10",GO:0016020//membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006417//regulation of translation;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,K12607//RNA degradation
25906,0,0,0,4,4,0,0,0,13,0,21,0,ANAPC15;anaphase promoting complex subunit 15,GO:0005622//intracellular;GO:0005680//anaphase-promoting complex,GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:0007067//mitotic nuclear division,-,-
25909,0,2,0,27,137,6,35,0,67,126,16,0,AHCTF1;AT hook containing transcription factor 1,GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0016363//nuclear matrix;GO:0000785//chromatin;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0070062//extracellular vesicular exosome;GO:0031080//nuclear pore outer ring;GO:0000777//condensed chromosome kinetochore,"GO:0051292//nuclear pore complex assembly;GO:0015031//protein transport;GO:0006355//regulation of transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0051028//mRNA transport;GO:0000910//cytokinesis",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K00907//Focal adhesion;Gastric acid secretion;Calcium signaling pathway;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
2591,0,0,0,4,18,0,0,0,0,0,0,0,GALNT3;polypeptide N-acetylgalactosaminyltransferase 3,GO:0048471//perinuclear region of cytoplasm;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0018243//protein O-linked glycosylation via threonine;GO:0005975//carbohydrate metabolic process;GO:0018242//protein O-linked glycosylation via serine,GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0030145//manganese ion binding;GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
25911,0,0,0,0,5,0,0,1,20,0,11,0,DPCD;deleted in primary ciliary dyskinesia homolog (mouse),GO:0005634//nucleus,GO:0021670//lateral ventricle development;GO:0021678//third ventricle development;GO:0007368//determination of left/right symmetry;GO:0030317//sperm motility;GO:0003351//epithelial cilium movement;GO:0007283//spermatogenesis;GO:0060972//left/right pattern formation,-,-
25913,0,0,0,3,1,0,0,0,1,0,5,0,POT1;protection of telomeres 1,"GO:0000783//nuclear telomere cap complex;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus",GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0007004//telomere maintenance via telomerase;GO:0032203//telomere formation via telomerase;GO:0060383//positive regulation of DNA strand elongation;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0051973//positive regulation of telomerase activity;GO:0051096//positive regulation of helicase activity;GO:0032508//DNA duplex unwinding;GO:0051974//negative regulation of telomerase activity;GO:0016233//telomere capping;GO:0000723//telomere maintenance,GO:0005515//protein binding;GO:0043047//single-stranded telomeric DNA binding;GO:0010521//telomerase inhibitor activity;GO:0017151//DEAD/H-box RNA helicase binding,-
25914,39,0,0,0,0,0,2,105,118,68,8,0,RTTN;rotatin,GO:0036064//ciliary basal body;GO:0005737//cytoplasm,GO:0007368//determination of left/right symmetry,-,-
25915,0,1,0,0,0,12,0,0,0,0,0,0,"NDUFAF3;NADH dehydrogenase (ubiquinone) complex I, assembly factor 3",GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane,GO:0032981//mitochondrial respiratory chain complex I assembly,GO:0005515//protein binding,-
25917,0,52,0,69,72,0,0,2,14,0,7,0,THUMPD3;THUMP domain containing 3,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0032259//methylation,GO:0003723//RNA binding;GO:0008168//methyltransferase activity,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
259173,59,0,0,0,0,0,0,54,26,94,9,0,ALS2CL;ALS2 C-terminal like,GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0032321//positive regulation of Rho GTPase activity;GO:0007032//endosome organization;GO:0008104//protein localization,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0042802//identical protein binding;GO:0005096//GTPase activator activity;GO:0017137//Rab GTPase binding,K04575//Amyotrophic lateral sclerosis (ALS)
2592,102,0,0,0,3,14,0,0,40,0,0,0,GALT;galactose-1-phosphate uridylyltransferase,GO:0005829//cytosol;GO:0005794//Golgi apparatus,GO:0044281//small molecule metabolic process;GO:0006012//galactose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019388//galactose catabolic process;GO:0006258//UDP-glucose catabolic process,GO:0008108//UDP-glucose:hexose-1-phosphate uridylyltransferase activity;GO:0008270//zinc ion binding,K00965//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Galactose metabolism;Jak-STAT signaling pathway;Metabolic pathways
25920,64,43,41,0,19,24,0,7,51,0,1,138,NELFB;negative elongation factor complex member B,GO:0005730//nucleolus;GO:0032021//NELF complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0050434//positive regulation of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process",GO:0005515//protein binding,-
25921,0,0,10,0,77,26,0,55,68,0,24,0,"ZDHHC5;zinc finger, DHHC-type containing 5",GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0018345//protein palmitoylation,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding,K05766//Regulation of actin cytoskeleton
259215,0,0,0,0,0,0,1,0,0,0,0,0,"LY6G6F;lymphocyte antigen 6 complex, locus G6F",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
259217,0,18,107,21,19,36,0,42,31,0,19,0,HSPA12A;heat shock 70kDa protein 12A,GO:0070062//extracellular vesicular exosome,-,GO:0005524//ATP binding,K03283//Influenza A;Legionellosis;Endocytosis;Spliceosome;Epstein-Barr virus infection;Antigen processing and presentation;Measles;MAPK signaling pathway;Toxoplasmosis;Protein processing in endoplasmic reticulum;Prion diseases
25923,0,31,0,23,93,11,1,100,38,0,8,0,ATL3;atlastin GTPase 3,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051260//protein homooligomerization;GO:0007029//endoplasmic reticulum organization;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0042802//identical protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
259230,0,0,1,1,23,37,0,0,27,0,11,0,SGMS1;sphingomyelin synthase 1,GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0030173//integral component of Golgi membrane;GO:0000138//Golgi trans cisterna;GO:0005634//nucleus,GO:0006686//sphingomyelin biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0016310//phosphorylation;GO:0016049//cell growth;GO:0006915//apoptotic process,GO:0047493//ceramide cholinephosphotransferase activity;GO:0033188//sphingomyelin synthase activity;GO:0016301//kinase activity,K04714//Metabolic pathways;Sphingolipid metabolism
259232,86,0,0,0,0,15,11,39,113,0,8,0,"NALCN;sodium leak channel, non-selective",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0030317//sperm motility;GO:0034220//ion transmembrane transport;GO:0008219//cell death;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import,GO:0005272//sodium channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding,K05668//ABC transporters;K04849//GABAergic synapse;Dopaminergic synapse;Nicotine addiction;Cholinergic synapse;Retrograde endocannabinoid signaling;Serotonergic synapse;Calcium signaling pathway;Synaptic vesicle cycle;Taste transduction;MAPK signaling pathway;Morphine addiction;Type II diabetes mellitus
259236,0,0,0,0,0,37,0,0,21,99,0,0,TMIE;transmembrane inner ear,GO:0016021//integral component of membrane,GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis,-,-
259239,0,0,0,0,0,0,43,0,0,0,0,0,WFDC11;WAP four-disulfide core domain 11,GO:0005576//extracellular region,-,-,-
25924,0,0,1,16,66,23,77,0,20,0,0,0,MYRIP;myosin VIIA and Rab interacting protein,GO:0015629//actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0042470//melanosome;GO:0031045//dense core granule;GO:0045202//synapse;GO:0001750//photoreceptor outer segment;GO:0030133//transport vesicle;GO:0000145//exocyst,GO:0032024//positive regulation of insulin secretion;GO:0006886//intracellular protein transport,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003779//actin binding;GO:0051018//protein kinase A binding;GO:0017137//Rab GTPase binding,-
259240,0,0,0,0,0,0,0,0,25,0,0,0,WFDC9;WAP four-disulfide core domain 9,GO:0005576//extracellular region,-,-,-
25925,0,0,0,0,0,11,0,187,33,0,0,0,ZNF521;zinc finger protein 521,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated",GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
25926,0,32,0,4,17,0,37,0,16,0,7,0,NOL11;nucleolar protein 11,GO:0005730//nucleolus;GO:0034455//t-UTP complex,"GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0006351//transcription, DNA-templated;GO:0030490//maturation of SSU-rRNA",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
259266,0,0,0,0,1,27,0,0,88,0,12,0,"ASPM;asp (abnormal spindle) homolog, microcephaly associated (Drosophila)",GO:0030496//midbody;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0048477//oogenesis;GO:0002052//positive regulation of neuroblast proliferation;GO:0045769//negative regulation of asymmetric cell division;GO:0007283//spermatogenesis;GO:0021873//forebrain neuroblast division;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0045665//negative regulation of neuron differentiation;GO:0001764//neuron migration;GO:0051661//maintenance of centrosome location;GO:0007067//mitotic nuclear division;GO:0048589//developmental growth,GO:0005516//calmodulin binding,-
25927,0,0,0,0,0,0,0,0,8,0,0,0,CNRIP1;cannabinoid receptor interacting protein 1,-,-,-,-
25928,0,0,0,0,12,15,0,0,18,0,0,0,SOSTDC1;sclerostin domain containing 1,GO:0005615//extracellular space,GO:0007389//pattern specification process;GO:0060648//mammary gland bud morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0010454//negative regulation of cell fate commitment;GO:0030514//negative regulation of BMP signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth,-,-
259282,0,1,1,0,51,39,11,0,47,0,0,0,BOD1L1;biorientation of chromosomes in cell division 1-like 1,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0003677//DNA binding,K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Gastric acid secretion;Calcium signaling pathway;Focal adhesion
259285,17,0,0,0,0,0,0,0,0,22,0,0,"TAS2R39;taste receptor, type 2, member 39",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
259286,0,0,0,0,0,0,0,0,6,0,0,0,"TAS2R40;taste receptor, type 2, member 40",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
259287,101,0,0,0,0,0,0,0,0,0,0,0,"TAS2R41;taste receptor, type 2, member 41",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
25929,16,1,0,0,31,81,104,0,33,98,0,0,GEMIN5;gem (nuclear organelle) associated protein 5,GO:0005829//cytosol;GO:0005634//nucleus;GO:0034719//SMN-Sm protein complex;GO:0097504//Gemini of coiled bodies;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm,"GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006461//protein complex assembly;GO:0010467//gene expression;GO:0016070//RNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0017069//snRNA binding,K13133//RNA transport
259290,0,0,0,0,0,0,0,0,19,0,0,0,"TAS2R31;taste receptor, type 2, member 31",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007186//G-protein coupled receptor signaling pathway,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
259293,0,0,0,0,0,0,36,0,0,0,0,0,"TAS2R30;taste receptor, type 2, member 30",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007186//G-protein coupled receptor signaling pathway,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
259294,0,0,0,0,0,21,0,102,14,0,0,0,"TAS2R19;taste receptor, type 2, member 19",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007186//G-protein coupled receptor signaling pathway,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
259296,0,0,0,0,0,0,0,0,26,0,0,0,"TAS2R50;taste receptor, type 2, member 50",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
2593,0,2,0,0,0,0,0,30,12,0,0,0,GAMT;guanidinoacetate N-methyltransferase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006600//creatine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006936//muscle contraction;GO:0009887//organ morphogenesis;GO:0007283//spermatogenesis;GO:0040014//regulation of multicellular organism growth;GO:0006601//creatine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0032259//methylation,GO:0030731//guanidinoacetate N-methyltransferase activity;GO:0008168//methyltransferase activity,"K00542//Metabolic pathways;Glycine, serine and threonine metabolism;Arginine and proline metabolism"
25930,99,1,0,9,0,28,40,8,36,0,8,261,"PTPN23;protein tyrosine phosphatase, non-receptor type 23",GO:0005737//cytoplasm;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0060271//cilium morphogenesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:2000643//positive regulation of early endosome to late endosome transport;GO:0010633//negative regulation of epithelial cell migration;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0015031//protein transport,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding,-
259307,0,0,0,0,0,0,71,72,29,0,0,0,IL4I1;interleukin 4 induced 1,GO:0005576//extracellular region;GO:0005764//lysosome,GO:0055114//oxidation-reduction process,GO:0001716//L-amino-acid oxidase activity,"K03334//Phenylalanine, tyrosine and tryptophan biosynthesis;Cysteine and methionine metabolism;Tryptophan metabolism;Tyrosine metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;Phenylalanine metabolism"
259308,118,0,0,0,18,2,0,0,19,0,0,0,"FAM205A;family with sequence similarity 205, member A",GO:0016021//integral component of membrane;GO:0005634//nucleus,-,-,-
25932,0,0,3,65,97,0,35,0,20,0,0,0,CLIC4;chloride intracellular channel 4,GO:0048471//perinuclear region of cytoplasm;GO:0016363//nuclear matrix;GO:0005622//intracellular;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0015630//microtubule cytoskeleton;GO:0030496//midbody;GO:0034707//chloride channel complex;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,GO:0035264//multicellular organism growth;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030336//negative regulation of cell migration;GO:0051493//regulation of cytoskeleton organization;GO:0071277//cellular response to calcium ion;GO:0006821//chloride transport;GO:0001525//angiogenesis;GO:0007035//vacuolar acidification;GO:0030216//keratinocyte differentiation;GO:0009566//fertilization;GO:0044070//regulation of anion transport;GO:0034765//regulation of ion transmembrane transport;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0030154//cell differentiation;GO:1902476//chloride transmembrane transport;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0001886//endothelial cell morphogenesis,GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding;GO:0005254//chloride channel activity,-
25934,0,0,0,8,24,0,0,0,10,0,0,0,NIPSNAP3A;nipsnap homolog 3A (C. elegans),GO:0005634//nucleus;GO:0005829//cytosol,-,GO:0005515//protein binding,-
25936,0,0,0,0,0,0,0,0,5,0,0,0,"NSL1;NSL1, MIS12 kinetochore complex component",GO:0005634//nucleus;GO:0000444//MIS12/MIND type complex;GO:0005829//cytosol,GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,-
25937,180,19,0,8,64,4,1,41,30,345,29,0,WWTR1;WW domain containing transcription regulator 1,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001649//osteoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0017145//stem cell division;GO:0035329//hippo signaling;GO:0060390//regulation of SMAD protein import into nucleus;GO:0032835//glomerulus development;GO:0060271//cilium morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0001933//negative regulation of protein phosphorylation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0010467//gene expression;GO:0045599//negative regulation of fat cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035414//negative regulation of catenin import into nucleus",GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity,K11447//Transcriptional misregulation in cancer;K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
25938,3,29,1,8,49,0,0,10,55,17,3,0,HEATR5A;HEAT repeat containing 5A,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
25939,0,0,0,5,41,0,0,113,12,0,36,0,SAMHD1;SAM domain and HD domain 1,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006203//dGTP catabolic process;GO:0046061//dATP catabolic process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0051289//protein homotetramerization;GO:0006955//immune response;GO:0045088//regulation of innate immune response,GO:0003676//nucleic acid binding;GO:0003723//RNA binding;GO:0032567//dGTP binding;GO:0005515//protein binding;GO:0008832//dGTPase activity;GO:0008270//zinc ion binding,K12830//Spliceosome
25940,0,35,0,0,21,33,0,0,33,0,0,0,"FAM98A;family with sequence similarity 98, member A",-,-,GO:0044822//poly(A) RNA binding,-
25941,0,34,1,12,41,0,27,101,62,1,0,0,TPGS2;tubulin polyglutamylase complex subunit 2,GO:0005874//microtubule;GO:0005737//cytoplasm,-,-,-
25942,0,65,1,28,117,16,0,0,174,0,0,0,SIN3A;SIN3 transcription regulator family member A,GO:0000776//kinetochore;GO:0017053//transcriptional repressor complex;GO:0016580//Sin3 complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031937//positive regulation of chromatin silencing;GO:0048511//rhythmic process;GO:0007568//aging;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:1901675//negative regulation of histone H3-K27 acetylation;GO:0010243//response to organonitrogen compound;GO:0002218//activation of innate immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034613//cellular protein localization;GO:0007596//blood coagulation;GO:0002230//positive regulation of defense response to virus by host;GO:1900181//negative regulation of protein localization to nucleus;GO:0071333//cellular response to glucose stimulus;GO:0006260//DNA replication;GO:0006476//protein deacetylation;GO:0044255//cellular lipid metabolic process;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0042754//negative regulation of circadian rhythm;GO:0001701//in utero embryonic development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0044281//small molecule metabolic process;GO:0006351//transcription, DNA-templated;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0043066//negative regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051595//response to methylglyoxal",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0032403//protein complex binding;GO:0033558//protein deacetylase activity;GO:0003682//chromatin binding;GO:0001103//RNA polymerase II repressing transcription factor binding,K11644//Transcriptional misregulation in cancer;Huntington's disease
25943,0,27,0,9,5,13,19,175,40,0,0,0,C20orf194;chromosome 20 open reading frame 194,-,-,-,-
25945,0,0,46,0,0,20,18,0,57,0,0,0,PVRL3;poliovirus receptor-related 3,GO:0043296//apical junction complex;GO:0005913//cell-cell adherens junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,GO:0034332//adherens junction organization;GO:0002089//lens morphogenesis in camera-type eye;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization;GO:0060042//retina morphogenesis in camera-type eye;GO:0009566//fertilization;GO:0034329//cell junction assembly;GO:0016337//single organismal cell-cell adhesion,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding,K06592//Adherens junction;Cell adhesion molecules (CAMs)
25946,0,0,1,0,6,33,1,1,30,256,18,0,ZNF385A;zinc finger protein 385A,GO:0005730//nucleolus;GO:0030425//dendrite;GO:0000790//nuclear chromatin;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:2000765//regulation of cytoplasmic translation;GO:0006915//apoptotic process;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0035855//megakaryocyte development;GO:0010609//mRNA localization resulting in posttranscriptional regulation of gene expression;GO:0006974//cellular response to DNA damage stimulus;GO:0007599//hemostasis;GO:0007626//locomotory behavior;GO:0030220//platelet formation;GO:0007611//learning or memory;GO:0070889//platelet alpha granule organization;GO:0045600//positive regulation of fat cell differentiation;GO:1902164//positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0006355//regulation of transcription, DNA-templated",GO:0002039//p53 binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0044822//poly(A) RNA binding,K10137//p53 signaling pathway
25948,0,0,0,29,25,1,0,0,37,0,1,0,KBTBD2;kelch repeat and BTB (POZ) domain containing 2,-,-,-,-
25949,0,0,0,0,8,0,0,0,34,0,0,0,SYF2;SYF2 pre-mRNA-splicing factor,GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome,"GO:0007095//mitotic G2 DNA damage checkpoint;GO:0048568//embryonic organ development;GO:0000398//mRNA splicing, via spliceosome;GO:0001701//in utero embryonic development;GO:0007369//gastrulation",GO:0044822//poly(A) RNA binding,K12868//Spliceosome
2595,0,0,0,0,9,13,0,0,57,0,0,0,"GANC;glucosidase, alpha; neutral C",-,GO:0005975//carbohydrate metabolic process,GO:0030246//carbohydrate binding;GO:0032450//maltose alpha-glucosidase activity,K12317//Starch and sucrose metabolism;Galactose metabolism;Metabolic pathways
25953,19,12,48,56,130,0,0,317,104,60,135,0,PNKD;paroxysmal nonkinesigenic dyskinesia,GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005634//nucleus,"GO:0050884//neuromuscular process controlling posture;GO:0006750//glutathione biosynthetic process;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0042053//regulation of dopamine metabolic process",GO:0004416//hydroxyacylglutathione hydrolase activity;GO:0008270//zinc ion binding,K01069//Pyruvate metabolism
25956,21,0,0,0,0,16,73,68,67,0,0,0,SEC31B;SEC31 homolog B (S. cerevisiae),GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0030120//vesicle coat,GO:0015031//protein transport;GO:0016192//vesicle-mediated transport,-,K14005//Protein processing in endoplasmic reticulum
25957,0,0,0,13,43,0,10,0,0,0,16,0,PNISR;PNN-interacting serine/arginine-rich protein,GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,-
25959,0,34,0,7,1,20,32,19,65,0,0,0,KANK2;KN motif and ankyrin repeat domains 2,GO:0005737//cytoplasm;GO:0005739//mitochondrion,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0043069//negative regulation of programmed cell death;GO:0006915//apoptotic process",GO:0005515//protein binding,K12460//Neurotrophin signaling pathway
2596,0,31,0,0,0,13,0,0,0,0,0,0,GAP43;growth associated protein 43,GO:0032584//growth cone membrane;GO:0005737//cytoplasm;GO:0031527//filopodium membrane;GO:0045202//synapse;GO:0030424//axon;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0042246//tissue regeneration;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0045165//cell fate commitment;GO:0040008//regulation of growth;GO:0051489//regulation of filopodium assembly;GO:0010001//glial cell differentiation;GO:0009611//response to wounding,GO:0005516//calmodulin binding;GO:0005515//protein binding,-
25960,0,29,0,20,57,13,43,0,30,0,88,0,GPR124;G protein-coupled receptor 124,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0043542//endothelial cell migration;GO:0002040//sprouting angiogenesis;GO:0045765//regulation of angiogenesis;GO:0007417//central nervous system development;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0050920//regulation of chemotaxis;GO:0090210//regulation of establishment of blood-brain barrier,GO:0004930//G-protein coupled receptor activity,-
25961,0,0,0,21,3,0,11,21,2,0,33,0,NUDT13;nudix (nucleoside diphosphate linked moiety X)-type motif 13,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K03426//Peroxisome;Nicotinate and nicotinamide metabolism
25962,0,0,0,16,130,46,0,5,64,186,0,27,KIAA1429;KIAA1429,GO:0005634//nucleus,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0044822//poly(A) RNA binding,K03350//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;Cell cycle
25963,80,21,0,1,56,19,25,66,12,0,43,259,TMEM87A;transmembrane protein 87A,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
25966,283,0,0,0,18,37,13,39,56,0,0,0,C2CD2;C2 calcium-dependent domain containing 2,GO:0005634//nucleus;GO:0005576//extracellular region;GO:0005829//cytosol,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2597,0,190,1,32,124,23,21,64,6,0,11,0,GAPDH;glyceraldehyde-3-phosphate dehydrogenase,GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005811//lipid particle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0097452//GAIT complex;GO:0031982//vesicle;GO:0005737//cytoplasm,GO:0000226//microtubule cytoskeleton organization;GO:0050821//protein stabilization;GO:0055114//oxidation-reduction process;GO:0051402//neuron apoptotic process;GO:0006094//gluconeogenesis;GO:0035606//peptidyl-cysteine S-trans-nitrosylation;GO:0006006//glucose metabolic process;GO:0017148//negative regulation of translation;GO:0006096//glycolytic process;GO:0071346//cellular response to interferon-gamma;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process,GO:0051287//NAD binding;GO:0035605//peptidyl-cysteine S-nitrosylase activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661//NADP binding,K00134//Alzheimer's disease;Microbial metabolism in diverse environments;Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis
25970,81,0,0,11,17,0,0,2,33,18,1,0,SH2B1;SH2B adaptor protein 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane,GO:0045840//positive regulation of mitosis;GO:2000278//regulation of DNA biosynthetic process;GO:0007596//blood coagulation;GO:0030032//lamellipodium assembly;GO:0006928//cellular component movement;GO:0035556//intracellular signal transduction,GO:0004871//signal transducer activity;GO:0005515//protein binding,K12459//Neurotrophin signaling pathway
25972,0,0,0,0,0,0,0,0,13,0,0,0,UNC50;unc-50 homolog (C. elegans),GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane,GO:0007166//cell surface receptor signaling pathway;GO:0015031//protein transport,GO:0003723//RNA binding,-
25973,0,0,0,0,9,0,0,50,19,0,0,0,"PARS2;prolyl-tRNA synthetase 2, mitochondrial (putative)",GO:0005759//mitochondrial matrix,GO:0006433//prolyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0004827//proline-tRNA ligase activity;GO:0005524//ATP binding,K01881//Aminoacyl-tRNA biosynthesis
25974,2,16,13,90,69,0,0,0,43,0,53,0,"MMACHC;methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria",GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0006766//vitamin metabolic process;GO:0009235//cobalamin metabolic process;GO:0009236//cobalamin biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0031419//cobalamin binding,K14618//Vitamin digestion and absorption
25975,0,0,0,0,0,0,32,0,0,109,0,0,"EGFL6;EGF-like-domain, multiple 6",GO:0016020//membrane;GO:0005615//extracellular space;GO:0005604//basement membrane,GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0007155//cell adhesion;GO:0007049//cell cycle;GO:0007275//multicellular organismal development,GO:0005178//integrin binding;GO:0005509//calcium ion binding,K06824//ECM-receptor interaction
25976,0,0,0,0,14,0,0,106,19,140,0,0,TIPARP;TCDD-inducible poly(ADP-ribose) polymerase,GO:0005634//nucleus,GO:0010629//negative regulation of gene expression;GO:0045732//positive regulation of protein catabolic process;GO:0006471//protein ADP-ribosylation;GO:0001822//kidney development;GO:0001570//vasculogenesis;GO:0048745//smooth muscle tissue development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0008585//female gonad development;GO:0060021//palate development;GO:0071407//cellular response to organic cyclic compound;GO:0060325//face morphogenesis;GO:0006807//nitrogen compound metabolic process;GO:0044236//multicellular organismal metabolic process;GO:0048705//skeletal system morphogenesis;GO:0009791//post-embryonic development;GO:0030097//hemopoiesis;GO:0008210//estrogen metabolic process;GO:0008209//androgen metabolic process,GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0035326//enhancer binding,-
25977,0,0,0,0,62,15,0,0,0,0,0,0,NECAP1;NECAP endocytosis associated 1,GO:0005905//coated pit;GO:0030125//clathrin vesicle coat;GO:0005886//plasma membrane,GO:0006897//endocytosis;GO:0015031//protein transport,-,-
25978,84,85,1,25,137,13,16,0,10,1,0,0,CHMP2B;charged multivesicular body protein 2B,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0019058//viral life cycle;GO:0016032//viral process;GO:0008219//cell death,GO:0019904//protein domain specific binding;GO:0005515//protein binding,K12192//Endocytosis
25979,1,0,0,0,0,9,16,0,1,0,0,0,DHRS7B;dehydrogenase/reductase (SDR family) member 7B,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
25980,0,0,0,0,5,0,0,2,1,0,0,0,AAR2;AAR2 splicing factor homolog (S. cerevisiae),-,-,-,-
25981,0,25,0,0,2,41,51,36,162,0,28,0,"DNAH1;dynein, axonemal, heavy chain 1",GO:0005858//axonemal dynein complex;GO:0030286//dynein complex;GO:0005874//microtubule,GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0003341//cilium movement;GO:0009612//response to mechanical stimulus;GO:0001539//cilium or flagellum-dependent cell motility,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,K10408//Huntington's disease
25983,0,26,0,4,54,0,0,0,0,0,0,0,"NGDN;neuroguidin, EIF4E binding protein","GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0030175//filopodium;GO:0030424//axon;GO:0005730//nucleolus;GO:0030425//dendrite",GO:0006417//regulation of translation,GO:0044822//poly(A) RNA binding,-
25984,0,0,0,0,0,10,24,0,29,0,27,70,KRT23;keratin 23 (histone deacetylase inducible),GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
25987,0,28,0,5,24,0,0,0,0,0,24,0,"TSKU;tsukushi, small leucine rich proteoglycan",GO:0005615//extracellular space,GO:0021960//anterior commissure morphogenesis;GO:0021670//lateral ventricle development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0061073//ciliary body morphogenesis;GO:0010468//regulation of gene expression;GO:0021540//corpus callosum morphogenesis,-,-
25988,0,0,0,0,0,0,24,18,21,0,7,15,HINFP;histone H4 transcription factor,GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0010629//negative regulation of gene expression;GO:0000077//DNA damage checkpoint;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045445//myoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0045184//establishment of protein localization;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0010628//positive regulation of gene expression",GO:0044212//transcription regulatory region DNA binding;GO:0042393//histone binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0003677//DNA binding,-
25989,92,0,0,17,0,0,32,0,42,134,0,0,ULK3;unc-51 like kinase 3,GO:0000407//pre-autophagosomal structure;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0034273//ATG1/UKL1 signaling complex,GO:0000045//autophagic vacuole assembly;GO:0006914//autophagy;GO:0090398//cellular senescence;GO:0010506//regulation of autophagy;GO:0045880//positive regulation of smoothened signaling pathway;GO:0046777//protein autophosphorylation;GO:0045879//negative regulation of smoothened signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K08269//mTOR signaling pathway;Regulation of autophagy
25992,0,55,80,98,43,11,16,146,0,1,195,0,"SNED1;sushi, nidogen and EGF-like domains 1",GO:0070062//extracellular vesicular exosome,GO:0007160//cell-matrix adhesion,GO:0005509//calcium ion binding,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
25994,0,0,1,19,191,0,0,164,24,0,0,2,"HIGD1A;HIG1 hypoxia inducible domain family, member 1A",GO:0016021//integral component of membrane;GO:0070469//respiratory chain;GO:0005743//mitochondrial inner membrane;GO:0043234//protein complex,GO:0055114//oxidation-reduction process;GO:0042149//cellular response to glucose starvation;GO:0071456//cellular response to hypoxia;GO:0043066//negative regulation of apoptotic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
25996,0,0,1,30,143,16,0,0,29,0,0,276,REXO2;RNA exonuclease 2,GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005758//mitochondrial intermembrane space;GO:0005925//focal adhesion;GO:0005739//mitochondrion,GO:0006139//nucleobase-containing compound metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0009117//nucleotide metabolic process,GO:0003676//nucleic acid binding;GO:0008408//3'-5' exonuclease activity,K13288//Ribosome biogenesis in eukaryotes
25999,0,0,0,0,15,0,0,69,48,0,13,0,CLIP3;CAP-GLY domain containing linker protein 3,GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0055038//recycling endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0005795//Golgi stack;GO:0031901//early endosome membrane;GO:0045121//membrane raft,GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0045807//positive regulation of endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0072321//chaperone-mediated protein transport;GO:0043065//positive regulation of apoptotic process;GO:0031115//negative regulation of microtubule polymerization;GO:0010828//positive regulation of glucose transport;GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0044091//membrane biogenesis;GO:0045444//fat cell differentiation,GO:0008017//microtubule binding;GO:0035594//ganglioside binding,-
26,0,0,0,0,0,0,24,0,34,0,8,0,"AOC1;amine oxidase, copper containing 1",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005923//tight junction;GO:0005615//extracellular space;GO:0005777//peroxisome,GO:0071504//cellular response to heparin;GO:0071280//cellular response to copper ion;GO:0035874//cellular response to copper ion starvation;GO:0035725//sodium ion transmembrane transport;GO:0055114//oxidation-reduction process;GO:0071420//cellular response to histamine;GO:0097185//cellular response to azide;GO:0046677//response to antibiotic;GO:0009308//amine metabolic process;GO:0042493//response to drug,"GO:0032403//protein complex binding;GO:0008144//drug binding;GO:0052597//diamine oxidase activity;GO:0005272//sodium channel activity;GO:0052600//propane-1,3-diamine oxidase activity;GO:0052599//methylputrescine oxidase activity;GO:0048038//quinone binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0004872//receptor activity;GO:0052598//histamine oxidase activity;GO:0005261//cation channel activity;GO:0005507//copper ion binding;GO:0008270//zinc ion binding;GO:0008201//heparin binding;GO:0008131//primary amine oxidase activity",K11182//Arginine and proline metabolism;Tryptophan metabolism;Histidine metabolism
26000,0,52,0,0,31,3,0,0,35,0,81,92,"TBC1D10B;TBC1 domain family, member 10B",GO:0005886//plasma membrane;GO:0005737//cytoplasm,"GO:0032313//regulation of Rab GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity",GO:0005097//Rab GTPase activator activity,K13136//RNA transport
26001,0,1,0,0,16,0,1,0,38,0,0,0,RNF167;ring finger protein 167,GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005737//cytoplasm,GO:0000209//protein polyubiquitination;GO:0045786//negative regulation of cell cycle,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
26002,0,0,0,0,0,0,0,0,37,19,0,0,"MOXD1;monooxygenase, DBH-like 1",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,"GO:0005507//copper ion binding;GO:0016715//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen",K00503//Metabolic pathways;Tyrosine metabolism
26003,0,35,0,17,41,20,0,39,13,0,0,0,"GORASP2;golgi reassembly stacking protein 2, 55kDa",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0000278//mitotic cell cycle;GO:0006996//organelle organization,GO:0005515//protein binding,-
26005,24,2,1,7,17,8,22,0,84,0,11,0,C2CD3;C2 calcium-dependent domain containing 3,GO:0005813//centrosome;GO:0034451//centriolar satellite;GO:0005814//centriole;GO:0036064//ciliary basal body,GO:0042733//embryonic digit morphogenesis;GO:0030162//regulation of proteolysis;GO:0001947//heart looping;GO:0008589//regulation of smoothened signaling pathway;GO:0007420//brain development;GO:0071539//protein localization to centrosome;GO:0021915//neural tube development;GO:0016485//protein processing;GO:0001701//in utero embryonic development;GO:0021997//neural plate axis specification;GO:0035058//nonmotile primary cilium assembly,GO:0005515//protein binding,-
26007,0,15,0,0,7,0,0,13,30,132,13,0,DAK;dihydroxyacetone kinase 2 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0046835//carbohydrate phosphorylation;GO:0044262//cellular carbohydrate metabolic process;GO:0045088//regulation of innate immune response;GO:0045087//innate immune response;GO:0006071//glycerol metabolic process,GO:0004371//glycerone kinase activity;GO:0046872//metal ion binding;GO:0050354//triokinase activity;GO:0005524//ATP binding;GO:0034012//FAD-AMP lyase (cyclizing) activity,K00863//RIG-I-like receptor signaling pathway;Methane metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Glycerolipid metabolism
26009,0,66,2,28,138,0,29,0,9,0,0,0,"ZZZ3;zinc finger, ZZ-type containing 3",GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,"GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
26010,74,0,0,17,20,13,3,26,48,191,20,0,"SPATS2L;spermatogenesis associated, serine-rich 2-like",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
26011,0,0,0,0,0,80,1,0,68,63,26,516,TENM4;teneurin transmembrane protein 4,GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043005//neuron projection,GO:0060038//cardiac muscle cell proliferation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0001702//gastrulation with mouth forming second;GO:2000543//positive regulation of gastrulation;GO:0007165//signal transduction;GO:0048666//neuron development;GO:0060912//cardiac cell fate specification;GO:0032289//central nervous system myelin formation;GO:0097264//self proteolysis;GO:0031643//positive regulation of myelination,GO:0042803//protein homodimerization activity,K06252//ECM-receptor interaction;Focal adhesion
26012,0,0,1,0,0,0,5,0,0,0,12,0,NSMF;NMDA receptor synaptonuclear signaling and neuronal migration factor,GO:0005634//nucleus;GO:0043204//perikaryon;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0030425//dendrite;GO:0045202//synapse;GO:0016020//membrane;GO:0043005//neuron projection;GO:0005635//nuclear envelope;GO:0016363//nuclear matrix;GO:0030863//cortical cytoskeleton;GO:0005719//nuclear euchromatin;GO:0031965//nuclear membrane;GO:0097440//apical dendrite;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0071230//cellular response to amino acid stimulus;GO:0048168//regulation of neuronal synaptic plasticity;GO:2001224//positive regulation of neuron migration;GO:0071257//cellular response to electrical stimulus;GO:0043523//regulation of neuron apoptotic process;GO:0048814//regulation of dendrite morphogenesis;GO:0071371//cellular response to gonadotropin stimulus;GO:0035307//positive regulation of protein dephosphorylation,GO:0048306//calcium-dependent protein binding,-
26013,0,0,0,0,0,32,19,0,22,0,0,0,L3MBTL1;l(3)mbt-like 1 (Drosophila),GO:0000785//chromatin;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000793//condensed chromosome;GO:0005730//nucleolus,"GO:0051726//regulation of cell cycle;GO:0007088//regulation of mitosis;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated;GO:0045652//regulation of megakaryocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030097//hemopoiesis",GO:0003682//chromatin binding;GO:0031491//nucleosome binding;GO:0032093//SAM domain binding;GO:0031493//nucleosomal histone binding;GO:0035064//methylated histone binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
26015,0,0,0,0,19,0,31,62,39,31,0,0,RPAP1;RNA polymerase II associated protein 1,GO:0005634//nucleus,GO:0032774//RNA biosynthetic process,GO:0003677//DNA binding;GO:0003899//DNA-directed RNA polymerase activity,-
26017,30,0,0,5,2,11,0,0,15,0,0,0,"FAM32A;family with sequence similarity 32, member A",GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0007049//cell cycle;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
26018,0,21,34,0,51,26,1,0,51,184,31,170,LRIG1;leucine-rich repeats and immunoglobulin-like domains 1,GO:0016021//integral component of membrane,GO:0060384//innervation;GO:0007605//sensory perception of sound;GO:0032474//otolith morphogenesis,-,K06753//Axon guidance
26019,0,33,1,75,184,30,65,0,73,0,10,0,UPF2;UPF2 regulator of nonsense transcripts homolog (yeast),GO:0035145//exon-exon junction complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001889//liver development;GO:0010467//gene expression;GO:0031100//organ regeneration;GO:0006406//mRNA export from nucleus",GO:0005515//protein binding;GO:0003723//RNA binding,K14327//RNA transport;mRNA surveillance pathway
26020,0,0,0,0,0,0,0,0,10,0,9,0,LRP10;low density lipoprotein receptor-related protein 10,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005905//coated pit,GO:0006897//endocytosis,-,K12473//Hepatitis C;Endocytosis;Toxoplasmosis;Bile secretion
26025,0,0,0,0,0,0,0,0,32,0,0,0,"PCDHGA12;protocadherin gamma subfamily A, 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
26027,8,0,0,0,0,18,41,0,44,0,0,265,ACOT11;acyl-CoA thioesterase 11,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0009266//response to temperature stimulus;GO:0009409//response to cold;GO:0006631//fatty acid metabolic process;GO:0035556//intracellular signal transduction,GO:0052689//carboxylic ester hydrolase activity;GO:0047617//acyl-CoA hydrolase activity;GO:0008289//lipid binding,-
260293,0,0,0,0,0,0,0,0,11,0,0,0,"CYP4X1;cytochrome P450, family 4, subfamily X, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0020037//heme binding,K07428//Serotonergic synapse
260294,0,0,1,24,0,0,0,0,0,0,41,2,"NSUN5P2;NOP2/Sun domain family, member 5 pseudogene 2",-,GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0003723//RNA binding,-
26031,0,0,0,0,0,37,67,31,83,115,8,0,OSBPL3;oxysterol binding protein-like 3,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0097038//perinuclear endoplasmic reticulum,GO:0006869//lipid transport,GO:0005515//protein binding;GO:0015485//cholesterol binding,-
26032,1,0,0,0,0,32,68,0,38,0,1,0,SUSD5;sushi domain containing 5,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0005540//hyaluronic acid binding,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
26033,1,0,0,0,0,30,25,89,42,157,0,0,ATRNL1;attractin-like 1,GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007275//multicellular organismal development,GO:0004872//receptor activity;GO:0030246//carbohydrate binding,K06243//Focal adhesion;Small cell lung cancer;Amoebiasis;ECM-receptor interaction;Toxoplasmosis;Pathways in cancer
26034,0,0,0,0,0,41,19,0,20,0,21,1,IPCEF1;interaction protein for cytohesin exchange factors 1,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0015671//oxygen transport;GO:0006979//response to oxidative stress;GO:0033126//positive regulation of GTP catabolic process;GO:0055114//oxidation-reduction process,GO:0019904//protein domain specific binding;GO:0004601//peroxidase activity;GO:0005344//oxygen transporter activity,K11447//Transcriptional misregulation in cancer;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
26035,0,0,0,4,12,0,0,0,34,0,0,0,GLCE;glucuronic acid epimerase,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030210//heparin biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,"GO:0016857//racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0050379//UDP-glucuronate 5'-epimerase activity;GO:0047464//heparosan-N-sulfate-glucuronate 5-epimerase activity",K01793//Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
26036,89,29,1,41,139,44,80,0,136,0,1,0,ZNF451;zinc finger protein 451,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
26037,18,1,4,8,1,25,25,0,63,6,0,0,SIPA1L1;signal-induced proliferation-associated 1 like 1,GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0014069//postsynaptic density,GO:0048167//regulation of synaptic plasticity;GO:0061001//regulation of dendritic spine morphogenesis;GO:0032861//activation of Rap GTPase activity;GO:0032317//regulation of Rap GTPase activity;GO:0031532//actin cytoskeleton reorganization;GO:0050770//regulation of axonogenesis;GO:0048013//ephrin receptor signaling pathway,GO:0046875//ephrin receptor binding;GO:0005096//GTPase activator activity,K08013//Leukocyte transendothelial migration
26038,0,0,0,0,0,79,73,64,38,0,28,0,CHD5;chromodomain helicase DNA binding protein 5,GO:0000792//heterochromatin;GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0016020//membrane,"GO:0006200//ATP catabolic process;GO:0043967//histone H4 acetylation;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0098532//histone H3-K27 trimethylation;GO:0021895//cerebral cortex neuron differentiation;GO:0008285//negative regulation of cell proliferation;GO:1901798//positive regulation of signal transduction by p53 class mediator;GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0008026//ATP-dependent helicase activity;GO:0005524//ATP binding,-
26040,0,0,0,0,66,12,14,0,16,0,3,0,SETBP1;SET binding protein 1,GO:0005634//nucleus,-,GO:0003677//DNA binding,K06101//Lysine degradation;Tight junction
260425,31,0,0,19,86,16,81,46,83,0,10,0,"MAGI3;membrane associated guanylate kinase, WW and PDZ domain containing 3",GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016020//membrane;GO:0005634//nucleus,GO:0006915//apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0016032//viral process;GO:0035556//intracellular signal transduction;GO:0046939//nucleotide phosphorylation,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005109//frizzled binding;GO:0004385//guanylate kinase activity,K06112//Tight junction
260429,0,0,0,0,6,0,0,0,9,0,0,0,"PRSS33;protease, serine, 33",GO:0005615//extracellular space,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
26043,0,1,0,20,135,0,0,0,20,0,7,0,UBXN7;UBX domain protein 7,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0034098//Cdc48p-Npl4p-Ufd1p AAA ATPase complex,-,GO:0043130//ubiquitin binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0008134//transcription factor binding,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K12756//Tight junction;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Focal adhesion
260434,0,0,0,0,0,0,0,0,11,0,0,0,PYDC1;PYD (pyrin domain) containing 1,GO:0005634//nucleus;GO:0008385//IkappaB kinase complex;GO:0005829//cytosol,GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006469//negative regulation of protein kinase activity;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0045087//innate immune response,GO:0005515//protein binding,K12799//Cytosolic DNA-sensing pathway;Salmonella infection;Pertussis;Legionellosis;Influenza A;NOD-like receptor signaling pathway;K12802//NOD-like receptor signaling pathway
260436,0,0,0,0,0,13,0,0,0,0,0,0,FDCSP;follicular dendritic cell secreted protein,GO:0005576//extracellular region,-,-,-
26045,0,0,0,0,0,0,0,0,11,0,0,0,LRRTM2;leucine rich repeat transmembrane neuronal 2,GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,GO:0060291//long-term synaptic potentiation;GO:0050808//synapse organization;GO:0002091//negative regulation of receptor internalization,GO:0042043//neurexin family protein binding,-
26046,0,0,1,32,278,10,58,0,57,173,16,0,LTN1;listerin E3 ubiquitin protein ligase 1,-,GO:0016567//protein ubiquitination,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
26047,0,56,0,0,101,12,0,0,83,0,0,0,CNTNAP2;contactin associated protein-like 2,GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0030425//dendrite;GO:0044224//juxtaparanode region of axon;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0008076//voltage-gated potassium channel complex;GO:0030424//axon;GO:0043204//perikaryon;GO:0030673//axolemma,GO:0021794//thalamus development;GO:0007155//cell adhesion;GO:0021987//cerebral cortex development;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0034613//cellular protein localization;GO:0021756//striatum development;GO:0071205//protein localization to juxtaparanode region of axon;GO:0007612//learning;GO:0021761//limbic system development;GO:0007420//brain development;GO:0008038//neuron recognition;GO:0019226//transmission of nerve impulse;GO:0071625//vocalization behavior;GO:0071109//superior temporal gyrus development;GO:0031175//neuron projection development;GO:0045163//clustering of voltage-gated potassium channels,GO:0019899//enzyme binding,K07380//Cell adhesion molecules (CAMs)
26048,0,0,0,0,1,0,11,0,20,0,8,0,ZNF500;zinc finger protein 500,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
26049,0,30,52,54,255,7,22,341,18,1,50,0,"FAM169A;family with sequence similarity 169, member A",GO:0005637//nuclear inner membrane,-,-,-
26050,0,0,0,0,0,3,0,12,10,0,0,0,"SLITRK5;SLIT and NTRK-like family, member 5",GO:0043235//receptor complex;GO:0016021//integral component of membrane,GO:0030534//adult behavior;GO:0048813//dendrite morphogenesis;GO:0043588//skin development;GO:0021756//striatum development;GO:0007268//synaptic transmission;GO:0009410//response to xenobiotic stimulus;GO:0072358//cardiovascular system development;GO:0007625//grooming behavior;GO:0007409//axonogenesis,-,-
26051,122,0,0,0,0,16,18,0,28,80,0,0,"PPP1R16B;protein phosphatase 1, regulatory subunit 16B",GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0007165//signal transduction;GO:0051489//regulation of filopodium assembly,GO:0005515//protein binding;GO:0019903//protein phosphatase binding,K12329//Vascular smooth muscle contraction
26052,0,0,0,0,3,20,31,0,111,1,19,0,DNM3;dynamin 3,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0048471//perinuclear region of cytoplasm;GO:0005874//microtubule;GO:0014069//postsynaptic density,GO:0046847//filopodium assembly;GO:0007416//synapse assembly;GO:0006184//GTP catabolic process;GO:0006897//endocytosis,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K01528//Endocytosis;Bacterial invasion of epithelial cells;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
26053,37,0,0,6,15,24,21,56,18,0,5,0,AUTS2;autism susceptibility candidate 2,-,-,-,-
26054,0,43,0,32,105,9,37,0,26,0,0,196,SENP6;SUMO1/sentrin specific peptidase 6,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0090169//regulation of spindle assembly;GO:0006508//proteolysis;GO:0090234//regulation of kinetochore assembly;GO:0016925//protein sumoylation;GO:0016926//protein desumoylation,GO:0005515//protein binding;GO:0016929//SUMO-specific protease activity,-
26056,1,0,0,0,11,14,38,0,65,0,7,0,RAB11FIP5;RAB11 family interacting protein 5 (class I),GO:0000139//Golgi membrane;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0030658//transport vesicle membrane;GO:0030141//secretory granule;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane;GO:0055038//recycling endosome membrane;GO:0055037//recycling endosome;GO:0005815//microtubule organizing center,GO:2000008//regulation of protein localization to cell surface;GO:0071468//cellular response to acidic pH;GO:0015031//protein transport;GO:0045055//regulated secretory pathway;GO:0035773//insulin secretion involved in cellular response to glucose stimulus,GO:0043015//gamma-tubulin binding;GO:0005515//protein binding,K12484//Endocytosis
26057,0,57,0,21,206,0,0,0,85,3,0,0,ANKRD17;ankyrin repeat domain 17,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,GO:0016032//viral process;GO:0001955//blood vessel maturation;GO:0051151//negative regulation of smooth muscle cell differentiation,GO:0044822//poly(A) RNA binding,-
26058,114,38,37,8,107,33,30,53,56,0,0,0,GIGYF2;GRB10 interacting GYF protein 2,GO:0016020//membrane,GO:0048873//homeostasis of number of cells within a tissue;GO:0050885//neuromuscular process controlling balance;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0044267//cellular protein metabolic process;GO:0007631//feeding behavior;GO:0021522//spinal cord motor neuron differentiation;GO:0050881//musculoskeletal movement;GO:0035264//multicellular organism growth;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0017148//negative regulation of translation;GO:0009791//post-embryonic development;GO:0008344//adult locomotory behavior;GO:0008219//cell death,GO:0044822//poly(A) RNA binding,-
26059,47,0,0,0,0,0,10,0,45,0,7,318,ERC2;ELKS/RAB6-interacting/CAST family member 2,GO:0042734//presynaptic membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005856//cytoskeleton;GO:0048786//presynaptic active zone,-,GO:0005515//protein binding,K16072//NF-kappa B signaling pathway
26060,142,0,0,47,78,22,27,2,53,7,0,527,"APPL1;adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1",GO:0012506//vesicle membrane;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005737//cytoplasm,GO:0046324//regulation of glucose import;GO:0008283//cell proliferation;GO:0090003//regulation of establishment of protein localization to plasma membrane;GO:0006915//apoptotic process;GO:0008286//insulin receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0042981//regulation of apoptotic process;GO:0007165//signal transduction;GO:0007049//cell cycle,GO:0043422//protein kinase B binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K08733//Colorectal cancer;Pathways in cancer
26061,0,0,0,10,31,18,5,0,13,0,0,0,HACL1;2-hydroxyacyl-CoA lyase 1,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,GO:0051259//protein oligomerization;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0001561//fatty acid alpha-oxidation,GO:0000287//magnesium ion binding;GO:0030976//thiamine pyrophosphate binding;GO:0005102//receptor binding;GO:0016830//carbon-carbon lyase activity;GO:0048037//cofactor binding;GO:0042802//identical protein binding,K12261//Peroxisome
26062,0,0,0,0,0,0,44,0,1,0,0,0,HYALP1;hyaluronoglucosaminidase pseudogene 1,-,-,-,"K01197//Metabolic pathways;Glycosaminoglycan degradation;Alanine, aspartate and glutamate metabolism;Lysosome;Arginine and proline metabolism"
26063,96,0,0,0,7,0,0,0,14,0,11,0,"DECR2;2,4-dienoyl CoA reductase 2, peroxisomal",GO:0005778//peroxisomal membrane,GO:0006636//unsaturated fatty acid biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity;GO:0005102//receptor binding",K13237//Peroxisome
26064,95,0,1,0,1,46,0,0,45,0,10,0,RAI14;retinoic acid induced 14,GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0005737//cytoplasm,-,-,-
26065,0,0,1,50,224,12,1,2,17,0,0,0,"LSM14A;LSM14A, SCD6 homolog A (S. cerevisiae)",GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0010494//cytoplasmic stress granule;GO:0043231//intracellular membrane-bounded organelle,GO:0007275//multicellular organismal development;GO:0039529//RIG-I signaling pathway;GO:0006417//regulation of translation;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0060340//positive regulation of type I interferon-mediated signaling pathway,GO:0044822//poly(A) RNA binding;GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003690//double-stranded DNA binding,-
26071,0,0,0,0,8,0,0,1,0,0,5,0,"FAM127B;family with sequence similarity 127, member B",-,-,-,-
26073,0,17,1,128,185,13,0,0,18,0,83,0,"POLDIP2;polymerase (DNA-directed), delta interacting protein 2",GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid,GO:0070584//mitochondrion morphogenesis,GO:0003677//DNA binding,-
26074,36,0,0,0,0,25,0,0,13,147,0,1,C20orf26;chromosome 20 open reading frame 26,-,-,-,K12869//Spliceosome
26080,61,0,0,0,0,0,18,3,44,256,2,0,"FAM230C;family with sequence similarity 230, member C",-,-,-,-
26083,75,0,0,0,0,0,0,0,6,0,0,0,"TBC1D29;TBC1 domain family, member 29",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,-
26084,0,39,4,18,115,0,19,0,35,0,33,0,ARHGEF26;Rho guanine nucleotide exchange factor (GEF) 26,GO:0001726//ruffle,GO:0001886//endothelial cell morphogenesis;GO:0032321//positive regulation of Rho GTPase activity;GO:0097178//ruffle assembly,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K13744//Bacterial invasion of epithelial cells
26085,0,0,0,0,0,0,65,32,27,0,0,0,KLK13;kallikrein-related peptidase 13,GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0030141//secretory granule;GO:0005615//extracellular space,GO:0006508//proteolysis;GO:0016485//protein processing,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0016787//hydrolase activity,-
26086,31,0,0,0,0,0,14,110,47,0,0,0,GPSM1;G-protein signaling modulator 1,GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030154//cell differentiation;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0050790//regulation of catalytic activity;GO:0007399//nervous system development,GO:0005092//GDP-dissociation inhibitor activity,K15839//Cocaine addiction
26088,0,25,1,3,21,0,0,0,16,0,11,89,"GGA1;golgi-associated, gamma adaptin ear containing, ARF binding protein 1",GO:0005634//nucleus;GO:0030131//clathrin adaptor complex;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0010008//endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane,GO:0006886//intracellular protein transport;GO:0045732//positive regulation of protein catabolic process;GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,K12404//Lysosome
26090,0,0,0,11,16,0,50,0,26,0,0,0,ABHD12;abhydrolase domain containing 12,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0006660//phosphatidylserine catabolic process;GO:0010996//response to auditory stimulus;GO:0007628//adult walking behavior,GO:0047372//acylglycerol lipase activity,-
26091,106,18,0,69,47,16,0,0,24,0,0,307,HERC4;HECT and RLD domain containing E3 ubiquitin protein ligase 4,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030154//cell differentiation;GO:0007283//spermatogenesis,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,K10615//Ubiquitin mediated proteolysis
26092,0,1,2,46,67,0,0,73,37,0,26,0,TOR1AIP1;torsin A interacting protein 1,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane,GO:0032781//positive regulation of ATPase activity,GO:0008092//cytoskeletal protein binding;GO:0051117//ATPase binding;GO:0001671//ATPase activator activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
26093,0,1,1,0,1,0,0,1,0,0,0,0,CCDC9;coiled-coil domain containing 9,-,-,GO:0044822//poly(A) RNA binding,-
26094,0,1,0,0,0,0,0,46,12,155,5,0,DCAF4;DDB1 and CUL4 associated factor 4,GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:0016567//protein ubiquitination,-,-
26095,0,0,0,0,0,0,60,0,21,0,0,0,"PTPN20B;protein tyrosine phosphatase, non-receptor type 20B",GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity,-
26097,0,219,52,23,59,0,17,22,15,96,59,0,CHTOP;chromatin target of PRMT1,GO:0005730//nucleolus;GO:0000346//transcription export complex;GO:0016607//nuclear speck,"GO:0006355//regulation of transcription, DNA-templated;GO:0051096//positive regulation of helicase activity;GO:0006406//mRNA export from nucleus;GO:0032781//positive regulation of ATPase activity;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
26098,0,0,0,8,48,0,20,0,68,6,5,0,EDRF1;erythroid differentiation regulatory factor 1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
26099,45,0,1,4,65,0,0,37,1,0,2,0,SZRD1;SUZ RNA binding domain containing 1,-,-,-,-
26100,0,1,0,22,73,0,87,3,62,0,3,450,"WIPI2;WD repeat domain, phosphoinositide interacting 2",GO:0005634//nucleus;GO:0005776//autophagic vacuole;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0000407//pre-autophagosomal structure;GO:0034045//pre-autophagosomal structure membrane,GO:0000046//autophagic vacuole fusion;GO:0000045//autophagic vacuole assembly,"GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005515//protein binding",-
26102,0,0,0,0,15,0,0,0,37,0,0,0,DKFZP434A062;uncharacterized LOC26102,-,-,-,-
26103,0,0,13,0,0,17,0,0,1,0,0,0,"LRIT1;leucine-rich repeat, immunoglobulin-like and transmembrane domains 1",GO:0030176//integral component of endoplasmic reticulum membrane,-,-,K06839//Axon guidance;K06838//Axon guidance
26108,0,9,30,26,77,51,0,0,73,0,0,0,PYGO1;pygopus family PHD finger 1,GO:0005634//nucleus,GO:0002244//hematopoietic progenitor cell differentiation;GO:0016055//Wnt signaling pathway;GO:0009791//post-embryonic development;GO:0001822//kidney development;GO:0034504//protein localization to nucleus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007289//spermatid nucleus differentiation,GO:0008270//zinc ion binding;GO:0005515//protein binding,K11433//Lysine degradation;K11447//Transcriptional misregulation in cancer
26112,0,0,0,0,23,13,38,46,22,0,11,0,CCDC69;coiled-coil domain containing 69,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K11447//Transcriptional misregulation in cancer
26115,291,153,41,86,121,0,47,50,138,19,171,0,"TANC2;tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2",-,GO:0001701//in utero embryonic development,-,-
26118,0,36,0,8,33,0,0,0,0,0,0,0,WSB1;WD repeat and SOCS box containing 1,GO:0005622//intracellular,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
26119,0,8,0,0,25,0,0,44,6,0,3,0,LDLRAP1;low density lipoprotein receptor adaptor protein 1,GO:0009898//cytoplasmic side of plasma membrane;GO:0005883//neurofilament;GO:0005769//early endosome;GO:0030121//AP-1 adaptor complex;GO:0005829//cytosol;GO:0030122//AP-2 adaptor complex;GO:0030424//axon;GO:0055037//recycling endosome;GO:0009925//basal plasma membrane,GO:0043393//regulation of protein binding;GO:0031623//receptor internalization;GO:0009967//positive regulation of signal transduction;GO:0090205//positive regulation of cholesterol metabolic process;GO:0090003//regulation of establishment of protein localization to plasma membrane;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0006810//transport;GO:0006898//receptor-mediated endocytosis;GO:0042632//cholesterol homeostasis;GO:0042982//amyloid precursor protein metabolic process;GO:0008203//cholesterol metabolic process;GO:0090118//receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport,"GO:0035591//signaling adaptor activity;GO:0035612//AP-2 adaptor complex binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035615//clathrin adaptor activity;GO:0030159//receptor signaling complex scaffold activity;GO:0001784//phosphotyrosine binding;GO:0001540//beta-amyloid binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0030276//clathrin binding",K12474//Endocytosis
26121,129,51,1,31,90,16,31,3,61,0,36,0,PRPF31;pre-mRNA processing factor 31,GO:0016607//nuclear speck;GO:0005687//U4 snRNP;GO:0015030//Cajal body;GO:0005634//nucleus;GO:0005684//U2-type spliceosomal complex;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0005690//U4atac snRNP;GO:0071339//MLL1 complex,"GO:0000244//spliceosomal tri-snRNP complex assembly;GO:0000398//mRNA splicing, via spliceosome",GO:0043021//ribonucleoprotein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0070990//snRNP binding,K12844//Spliceosome
26122,0,21,0,6,5,43,0,0,25,0,0,0,EPC2;enhancer of polycomb homolog 2 (Drosophila),GO:0032777//Piccolo NuA4 histone acetyltransferase complex,"GO:0006351//transcription, DNA-templated;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair",-,-
26123,0,0,0,0,8,0,58,0,20,0,0,0,TCTN3;tectonic family member 3,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007224//smoothened signaling pathway;GO:0060271//cilium morphogenesis;GO:0006915//apoptotic process,-,K12657//Metabolic pathways;Arginine and proline metabolism
26127,0,1,0,4,95,0,0,0,54,0,0,0,FGFR1OP2;FGFR1 oncogene partner 2,GO:0005829//cytosol,GO:0042060//wound healing,GO:0042803//protein homodimerization activity,K12656//RIG-I-like receptor signaling pathway
26128,43,0,1,12,34,0,20,1,12,0,0,0,KIAA1279;KIAA1279,GO:0005739//mitochondrion;GO:0005856//cytoskeleton,GO:0007399//nervous system development;GO:0006839//mitochondrial transport;GO:0030154//cell differentiation,GO:0019894//kinesin binding;GO:0005515//protein binding,-
26130,54,1,2,9,105,13,0,2,192,0,1,469,GAPVD1;GTPase activating protein and VPS9 domains 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0005768//endosome,GO:0006897//endocytosis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051223//regulation of protein transport;GO:0043547//positive regulation of GTPase activity;GO:0007165//signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032794//GTPase activating protein binding;GO:0005096//GTPase activator activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K05767//Regulation of actin cytoskeleton;Adherens junction
26133,0,0,1,29,75,0,132,24,24,132,9,0,"TRPC4AP;transient receptor potential cation channel, subfamily C, member 4 associated protein",GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005886//plasma membrane,GO:0016567//protein ubiquitination;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0034220//ion transmembrane transport,GO:0019902//phosphatase binding;GO:0005515//protein binding,-
26134,0,0,42,0,0,0,0,0,0,0,6,0,"RALGAPA1P;Ral GTPase activating protein, alpha subunit 1 (catalytic) pseudogene",-,-,-,K07207//Insulin signaling pathway;mTOR signaling pathway;p53 signaling pathway
26135,0,269,0,173,426,0,22,0,57,0,3,0,SERBP1;SERPINE1 mRNA binding protein 1,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0043488//regulation of mRNA stability;GO:0042981//regulation of apoptotic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003730//mRNA 3'-UTR binding,-
26136,45,0,0,5,14,32,22,58,18,0,0,0,TES;testis derived transcript (3 LIM domains),GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex,GO:0008285//negative regulation of cell proliferation,GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,K04511//Wnt signaling pathway
26137,79,262,6,462,1627,36,16,1,139,0,20,0,ZBTB20;zinc finger and BTB domain containing 20,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
26138,0,0,0,0,0,14,0,1,54,121,3,0,LINC00588;long intergenic non-protein coding RNA 588,-,-,-,-
26140,0,0,0,1,0,0,0,0,21,0,0,0,"TTLL3;tubulin tyrosine ligase-like family, member 3",GO:0005930//axoneme;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005929//cilium,GO:0018094//protein polyglycylation;GO:0035082//axoneme assembly;GO:0042384//cilium assembly,"GO:0070735//protein-glycine ligase activity;GO:0070736//protein-glycine ligase activity, initiating",K15010//Glutamatergic synapse;K05755//Shigellosis;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Salmonella infection
26145,0,0,1,1,2,0,0,0,20,0,2,0,IRF2BP1;interferon regulatory factor 2 binding protein 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
26146,0,22,1,7,33,0,20,0,25,155,0,0,TRAF3IP1;TNF receptor-associated factor 3 interacting protein 1,GO:0005813//centrosome;GO:0005930//axoneme;GO:0036064//ciliary basal body;GO:0005929//cilium;GO:0030992//intraciliary transport particle B,GO:0050687//negative regulation of defense response to virus;GO:0035050//embryonic heart tube development;GO:0032688//negative regulation of interferon-beta production;GO:0036342//post-anal tail morphogenesis;GO:0042073//intraciliary transport;GO:0042733//embryonic digit morphogenesis;GO:0031076//embryonic camera-type eye development;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0042384//cilium assembly;GO:0021532//neural tube patterning,GO:0008017//microtubule binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
26147,0,0,0,0,7,30,37,0,19,0,0,0,PHF19;PHD finger protein 19,GO:0035098//ESC/E(Z) complex,"GO:0016568//chromatin modification;GO:0061087//positive regulation of histone H3-K27 methylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0006351//transcription, DNA-templated",GO:0035064//methylated histone binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
26148,1,16,0,46,35,10,15,0,15,0,0,0,C10orf12;chromosome 10 open reading frame 12,-,-,-,K04574//Amyotrophic lateral sclerosis (ALS)
26149,205,0,0,4,6,9,1,0,0,0,0,0,ZNF658;zinc finger protein 658,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
2615,0,0,0,0,0,0,0,3,6,0,17,0,LRRC32;leucine rich repeat containing 32,GO:0005887//integral component of plasma membrane,GO:0050710//negative regulation of cytokine secretion;GO:0046007//negative regulation of activated T cell proliferation;GO:0010628//positive regulation of gene expression,-,K05401//Herpes simplex infection;Hepatitis C;Influenza A;Toll-like receptor signaling pathway
26150,0,0,0,0,0,0,0,0,16,0,0,0,RIBC2;RIB43A domain with coiled-coils 2,GO:0005634//nucleus,-,-,-
26151,0,0,0,0,0,0,1,0,15,0,20,0,"NAT9;N-acetyltransferase 9 (GCN5-related, putative)",GO:0043234//protein complex,GO:0008152//metabolic process,GO:0008080//N-acetyltransferase activity,-
26152,83,0,0,34,46,18,0,114,84,0,42,0,ZNF337;zinc finger protein 337,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
26153,0,0,0,0,6,37,0,11,102,0,0,0,KIF26A;kinesin family member 26A,GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005874//microtubule,GO:0009968//negative regulation of signal transduction;GO:0008152//metabolic process;GO:0048484//enteric nervous system development;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation;GO:0007018//microtubule-based movement;GO:0001560//regulation of cell growth by extracellular stimulus,GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
26154,84,0,0,0,9,13,2,0,74,0,4,176,"ABCA12;ATP-binding cassette, sub-family A (ABC1), member 12",GO:0097209//epidermal lamellar body;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005829//cytosol,GO:0061436//establishment of skin barrier;GO:0006869//lipid transport;GO:0033700//phospholipid efflux;GO:0031424//keratinization;GO:0045055//regulated secretory pathway;GO:0072659//protein localization to plasma membrane;GO:2000010//positive regulation of protein localization to cell surface;GO:0019725//cellular homeostasis;GO:0048286//lung alveolus development;GO:0006200//ATP catabolic process;GO:0035627//ceramide transport;GO:0010875//positive regulation of cholesterol efflux;GO:0055088//lipid homeostasis;GO:0043129//surfactant homeostasis;GO:0032940//secretion by cell,GO:0005524//ATP binding;GO:0005319//lipid transporter activity;GO:0005102//receptor binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0034040//lipid-transporting ATPase activity;GO:0005515//protein binding,K05646//ABC transporters
26155,0,15,51,40,99,0,0,0,65,0,5,0,NOC2L;nucleolar complex associated 2 homolog (S. cerevisiae),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0032066//nucleolus to nucleoplasm transport;GO:0002903//negative regulation of B cell apoptotic process;GO:0031497//chromatin assembly;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0034644//cellular response to UV;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0035067//negative regulation of histone acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0070491//repressing transcription factor binding;GO:0003682//chromatin binding;GO:0031491//nucleosome binding;GO:0003714//transcription corepressor activity,-
26156,0,65,0,39,104,0,0,0,37,23,4,0,RSL1D1;ribosomal L1 domain containing 1,GO:0005730//nucleolus;GO:0016020//membrane,GO:0032880//regulation of protein localization;GO:0042981//regulation of apoptotic process;GO:0001649//osteoblast differentiation;GO:2000772//regulation of cellular senescence,GO:0044822//poly(A) RNA binding,-
26157,0,0,0,0,0,0,34,0,25,0,0,0,"GIMAP2;GTPase, IMAP family member 2",GO:0016021//integral component of membrane;GO:0005811//lipid particle;GO:0005737//cytoplasm,-,GO:0005525//GTP binding,K05305//Fructose and mannose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism
26160,0,23,33,4,28,47,17,0,118,0,45,0,IFT172;intraflagellar transport 172,GO:0030992//intraciliary transport particle B;GO:0036064//ciliary basal body;GO:0005929//cilium;GO:0031982//vesicle;GO:0005930//axoneme;GO:0097225//sperm midpiece;GO:0097228//sperm principal piece,GO:0061525//hindgut development;GO:0060173//limb development;GO:0060021//palate development;GO:0031122//cytoplasmic microtubule organization;GO:0007420//brain development;GO:0009953//dorsal/ventral pattern formation;GO:0008544//epidermis development;GO:0021522//spinal cord motor neuron differentiation;GO:0001947//heart looping;GO:0050680//negative regulation of epithelial cell proliferation;GO:0007219//Notch signaling pathway;GO:0001843//neural tube closure;GO:0016485//protein processing;GO:0007224//smoothened signaling pathway;GO:0042384//cilium assembly;GO:0060348//bone development;GO:0070986//left/right axis specification;GO:0045880//positive regulation of smoothened signaling pathway,-,-
26164,0,0,0,0,0,8,0,34,14,0,4,0,MTG2;mitochondrial ribosome-associated GTPase 2,GO:0005761//mitochondrial ribosome;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0006184//GTP catabolic process;GO:0044065//regulation of respiratory system process;GO:0042254//ribosome biogenesis;GO:0070129//regulation of mitochondrial translation,GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
26166,92,2,1,18,0,1,0,0,43,0,0,0,RGS22;regulator of G-protein signaling 22,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,-
26167,0,0,0,0,0,0,0,0,8,237,0,0,PCDHB5;protocadherin beta 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly,GO:0005509//calcium ion binding,-
26168,0,6,0,0,0,0,0,0,0,0,0,0,SENP3;SUMO1/sentrin/SMT3 specific peptidase 3,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0071339//MLL1 complex,GO:0006508//proteolysis,GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity,-
2617,0,79,1,25,136,32,0,0,5,0,0,0,GARS;glycyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030141//secretory granule,GO:0015966//diadenosine tetraphosphate biosynthetic process;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression;GO:0006426//glycyl-tRNA aminoacylation;GO:0008219//cell death,GO:0004820//glycine-tRNA ligase activity;GO:0046983//protein dimerization activity;GO:0005524//ATP binding,K01880//Aminoacyl-tRNA biosynthesis
261726,0,0,0,28,113,0,0,0,25,0,0,0,TIPRL;TOR signaling pathway regulator,GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle,GO:0000077//DNA damage checkpoint;GO:0034048//negative regulation of protein phosphatase type 2A activity,GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
261729,76,22,0,90,390,0,6,0,56,0,17,0,"STEAP2;STEAP family member 2, metalloreductase",GO:0030173//integral component of Golgi membrane;GO:0005886//plasma membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0005769//early endosome;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005829//cytosol,GO:0006893//Golgi to plasma membrane transport;GO:0045055//regulated secretory pathway;GO:0009725//response to hormone;GO:0055072//iron ion homeostasis;GO:0006897//endocytosis;GO:0055114//oxidation-reduction process;GO:0015677//copper ion import,GO:0046872//metal ion binding;GO:0005215//transporter activity,K14738//Mineral absorption
26173,184,0,0,0,13,34,22,168,55,1,15,61,INTS1;integrator complex subunit 1,GO:0031965//nuclear membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0032039//integrator complex,GO:0001833//inner cell mass cell proliferation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0034474//U2 snRNA 3'-end processing;GO:0043066//negative regulation of apoptotic process;GO:0016180//snRNA processing,-,-
261734,0,0,0,0,1,1,19,0,57,0,0,74,NPHP4;nephronophthisis 4,GO:0031513//nonmotile primary cilium;GO:0005813//centrosome;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0005829//cytosol;GO:0005923//tight junction,GO:0035329//hippo signaling;GO:0016337//single organismal cell-cell adhesion;GO:0007165//signal transduction;GO:0007632//visual behavior;GO:0030036//actin cytoskeleton organization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060041//retina development in camera-type eye,GO:0005198//structural molecule activity;GO:0005515//protein binding,-
26175,0,1,0,4,44,0,0,0,1,0,0,320,TMEM251;transmembrane protein 251,GO:0016021//integral component of membrane,-,-,-
2618,83,0,0,0,41,0,0,0,47,0,0,0,"GART;phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006144//purine nucleobase metabolic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0009113//purine nucleobase biosynthetic process;GO:0006544//glycine metabolic process;GO:0046654//tetrahydrofolate biosynthetic process;GO:0003360//brainstem development;GO:0021987//cerebral cortex development;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0032259//methylation;GO:0010035//response to inorganic substance;GO:0010033//response to organic substance;GO:0021549//cerebellum development,GO:0004637//phosphoribosylamine-glycine ligase activity;GO:0004644//phosphoribosylglycinamide formyltransferase activity;GO:0046872//metal ion binding;GO:0004641//phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0005524//ATP binding;GO:0008168//methyltransferase activity,K11787//Purine metabolism;Biosynthesis of secondary metabolites;One carbon pool by folate;Metabolic pathways
26184,0,0,0,9,0,7,0,0,14,0,0,0,"OR1F2P;olfactory receptor, family 1, subfamily F, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26188,0,0,0,8,0,0,0,0,1,0,0,0,"OR1C1;olfactory receptor, family 1, subfamily C, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26189,61,0,0,0,0,0,0,0,10,0,0,0,"OR1A2;olfactory receptor, family 1, subfamily A, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0032467//positive regulation of cytokinesis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2619,0,0,40,4,0,18,0,41,0,0,0,0,GAS1;growth arrest-specific 1,GO:0005886//plasma membrane;GO:0046658//anchored component of plasma membrane;GO:0016021//integral component of membrane,GO:0010955//negative regulation of protein processing;GO:0042474//middle ear morphogenesis;GO:0042476//odontogenesis;GO:0042981//regulation of apoptotic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0007050//cell cycle arrest;GO:0048589//developmental growth;GO:0048592//eye morphogenesis;GO:0012501//programmed cell death;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045165//cell fate commitment;GO:0021904//dorsal/ventral neural tube patterning;GO:0045930//negative regulation of mitotic cell cycle;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0043010//camera-type eye development;GO:0042733//embryonic digit morphogenesis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0042473//outer ear morphogenesis;GO:0021587//cerebellum morphogenesis;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0043066//negative regulation of apoptotic process;GO:0007411//axon guidance;GO:0060021//palate development;GO:0008589//regulation of smoothened signaling pathway;GO:0030308//negative regulation of cell growth;GO:0045879//negative regulation of smoothened signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation,GO:0005515//protein binding,K06232//Hedgehog signaling pathway
26190,13,21,0,58,145,2,0,102,32,190,0,0,FBXW2;F-box and WD repeat domain containing 2,GO:0005737//cytoplasm,GO:0006464//cellular protein modification process;GO:0006508//proteolysis;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
26191,154,0,0,0,0,13,21,0,28,0,0,0,"PTPN22;protein tyrosine phosphatase, non-receptor type 22 (lymphoid)",GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0009898//cytoplasmic side of plasma membrane,GO:0035644//phosphoanandamide dephosphorylation;GO:0045088//regulation of innate immune response;GO:0032817//regulation of natural killer cell proliferation;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0030217//T cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0050868//negative regulation of T cell activation;GO:0006470//protein dephosphorylation;GO:0050855//regulation of B cell receptor signaling pathway,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0019900//kinase binding,-
262,0,378,10,782,2407,0,0,0,0,0,1,0,AMD1;adenosylmethionine decarboxylase 1,GO:0005829//cytosol,GO:0006595//polyamine metabolic process;GO:0044281//small molecule metabolic process;GO:0006557//S-adenosylmethioninamine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006597//spermine biosynthetic process;GO:0008295//spermidine biosynthetic process,GO:0004014//adenosylmethionine decarboxylase activity,K01611//Cysteine and methionine metabolism;Arginine and proline metabolism;Metabolic pathways
2620,0,0,0,0,0,10,0,0,10,0,0,0,GAS2;growth arrest-specific 2,GO:0016020//membrane;GO:0005829//cytosol;GO:0005884//actin filament,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0008360//regulation of cell shape;GO:0007050//cell cycle arrest;GO:0006915//apoptotic process,-,-
26205,0,0,0,10,3,0,0,163,64,0,36,0,GMEB2;glucocorticoid modulatory element binding protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003713//transcription coactivator activity,-
26206,0,0,0,0,0,0,0,0,19,0,0,0,SPAG8;sperm associated antigen 8,GO:0016020//membrane;GO:0001669//acrosomal vesicle;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032092//positive regulation of protein binding,GO:0008017//microtubule binding,-
26207,0,0,0,9,17,11,0,0,68,0,11,185,"PITPNC1;phosphatidylinositol transfer protein, cytoplasmic 1",GO:0005737//cytoplasm,GO:0015914//phospholipid transport;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008526//phosphatidylinositol transporter activity,K01106//Phosphatidylinositol signaling system;Metabolic pathways;Insulin signaling pathway;Inositol phosphate metabolism
2621,6,4,0,0,2,23,23,0,58,0,2,0,GAS6;growth arrest-specific 6,GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0085029//extracellular matrix assembly;GO:0050711//negative regulation of interleukin-1 secretion;GO:0035457//cellular response to interferon-alpha;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070527//platelet aggregation;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0030168//platelet activation;GO:0050766//positive regulation of phagocytosis;GO:0007050//cell cycle arrest;GO:0009267//cellular response to starvation;GO:0016477//cell migration;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:2000533//negative regulation of renal albumin absorption;GO:0070168//negative regulation of biomineral tissue development;GO:0007155//cell adhesion;GO:0035754//B cell chemotaxis;GO:1900142//negative regulation of oligodendrocyte apoptotic process;GO:0032720//negative regulation of tumor necrosis factor production;GO:0046718//viral entry into host cell;GO:0097028//dendritic cell differentiation;GO:1900165//negative regulation of interleukin-6 secretion;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0071307//cellular response to vitamin K;GO:0040008//regulation of growth;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0045860//positive regulation of protein kinase activity;GO:0050900//leukocyte migration;GO:0018105//peptidyl-serine phosphorylation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0032715//negative regulation of interleukin-6 production;GO:0044267//cellular protein metabolic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0010934//macrophage cytokine production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032689//negative regulation of interferon-gamma production;GO:0043491//protein kinase B signaling;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0048146//positive regulation of fibroblast proliferation;GO:0008283//cell proliferation;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0032008//positive regulation of TOR signaling;GO:0032148//activation of protein kinase B activity;GO:0006909//phagocytosis;GO:0031589//cell-substrate adhesion;GO:0046827//positive regulation of protein export from nucleus;GO:0001934//positive regulation of protein phosphorylation;GO:0071333//cellular response to glucose stimulus;GO:0070588//calcium ion transmembrane transport;GO:0002576//platelet degranulation;GO:0001764//neuron migration;GO:0007596//blood coagulation;GO:0072661//protein targeting to plasma membrane;GO:0031100//organ regeneration;GO:0003104//positive regulation of glomerular filtration;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0043277//apoptotic cell clearance;GO:0046813//receptor-mediated virion attachment to host cell;GO:0035690//cellular response to drug;GO:0007165//signal transduction;GO:0043687//post-translational protein modification;GO:0006468//protein phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0006508//proteolysis;GO:0019079//viral genome replication;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade","GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0060090//binding, bridging;GO:0005102//receptor binding;GO:0048018//receptor agonist activity;GO:0030296//protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding",-
26211,293,0,0,0,0,0,0,0,0,0,0,0,"OR2F1;olfactory receptor, family 2, subfamily F, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
26212,0,0,0,0,0,0,0,0,16,0,0,0,"OR2B6;olfactory receptor, family 2, subfamily B, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26219,0,0,0,0,0,0,0,0,8,0,0,0,"OR1J4;olfactory receptor, family 1, subfamily J, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2622,107,0,0,0,20,0,0,17,29,0,31,0,GAS8;growth arrest-specific 8,GO:0005874//microtubule;GO:0031514//motile cilium;GO:0005794//Golgi apparatus,GO:0034613//cellular protein localization;GO:0008285//negative regulation of cell proliferation;GO:0030317//sperm motility,GO:0017137//Rab GTPase binding,K07127//Metabolic pathways;Microbial metabolism in diverse environments;Purine metabolism;K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
26220,85,0,0,0,0,0,41,0,11,78,17,0,DGCR5;DiGeorge syndrome critical region gene 5 (non-protein coding),-,-,-,-
26223,0,0,0,0,0,0,29,0,16,0,0,0,FBXL21;F-box and leucine-rich repeat protein 21 (gene/pseudogene),GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus,GO:0043153//entrainment of circadian clock by photoperiod;GO:0016567//protein ubiquitination;GO:0048511//rhythmic process,GO:0004842//ubiquitin-protein transferase activity,-
26224,0,70,0,66,99,10,0,0,23,0,18,0,FBXL3;F-box and leucine-rich repeat protein 3,GO:0000151//ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0048511//rhythmic process;GO:0042752//regulation of circadian rhythm;GO:0016567//protein ubiquitination;GO:0031648//protein destabilization;GO:0043153//entrainment of circadian clock by photoperiod;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K10269//Circadian rhythm - mammal
26225,0,15,0,33,150,0,0,0,12,34,0,0,ARL5A;ADP-ribosylation factor-like 5A,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
26226,0,0,0,0,0,0,7,0,56,0,0,0,FBXW4P1;F-box and WD repeat domain containing 4 pseudogene 1,-,-,-,-
26227,50,103,5,26,45,0,9,3,20,104,5,0,PHGDH;phosphoglycerate dehydrogenase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0021510//spinal cord development;GO:0031175//neuron projection development;GO:0044281//small molecule metabolic process;GO:0070314//G1 to G0 transition;GO:0021782//glial cell development;GO:0007420//brain development;GO:0006544//glycine metabolic process;GO:0006541//glutamine metabolic process;GO:0006566//threonine metabolic process;GO:0019530//taurine metabolic process;GO:0021915//neural tube development;GO:0055114//oxidation-reduction process;GO:0010468//regulation of gene expression;GO:0009448//gamma-aminobutyric acid metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006564//L-serine biosynthetic process,GO:0051287//NAD binding;GO:0009055//electron carrier activity;GO:0004617//phosphoglycerate dehydrogenase activity,"K00058//Chloroalkane and chloroalkene degradation;Metabolic pathways;Fructose and mannose metabolism;Glycine, serine and threonine metabolism;Methane metabolism;Microbial metabolism in diverse environments;Butanoate metabolism;Bisphenol degradation"
26228,0,0,0,0,0,0,0,0,12,23,0,0,STAP1;signal transducing adaptor family member 1,GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0006886//intracellular protein transport;GO:0009967//positive regulation of signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007165//signal transduction;GO:0061025//membrane fusion,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K00901//Metabolic pathways;Glycerolipid metabolism;Phosphatidylinositol signaling system;Glycerophospholipid metabolism
26229,0,0,0,0,0,0,19,1,13,0,0,0,"B3GAT3;beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)",GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process,GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0046872//metal ion binding;GO:0015020//glucuronosyltransferase activity,K10158//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate;Glycosaminoglycan biosynthesis - heparan sulfate
2623,0,0,0,0,0,9,0,0,0,0,0,0,GATA1;GATA binding protein 1 (globin transcription factor 1),GO:0017053//transcriptional repressor complex;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0030220//platelet formation;GO:0097067//cellular response to thyroid hormone stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008584//male gonad development;GO:0071733//transcriptional activation by promoter-enhancer looping;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0007596//blood coagulation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0006366//transcription from RNA polymerase II promoter;GO:0035162//embryonic hemopoiesis;GO:0030221//basophil differentiation;GO:0097028//dendritic cell differentiation;GO:0035854//eosinophil fate commitment;GO:0048821//erythrocyte development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001701//in utero embryonic development;GO:0030218//erythrocyte differentiation;GO:0030502//negative regulation of bone mineralization;GO:0007267//cell-cell signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070527//platelet aggregation;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010559//regulation of glycoprotein biosynthetic process;GO:0030222//eosinophil differentiation;GO:0033690//positive regulation of osteoblast proliferation;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0045648//positive regulation of erythrocyte differentiation;GO:0030219//megakaryocyte differentiation,"GO:0070742//C2H2 zinc finger domain binding;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0002039//p53 binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008301//DNA binding, bending;GO:0001158//enhancer sequence-specific DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding",-
26230,33,45,30,45,26,26,0,0,37,0,26,0,TIAM2;T-cell lymphoma invasion and metastasis 2,GO:0005829//cytosol;GO:0016020//membrane;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0030027//lamellipodium;GO:0030426//growth cone,GO:0007264//small GTPase mediated signal transduction;GO:0044255//cellular lipid metabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0044281//small molecule metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005057//receptor signaling protein activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity,K05731//Regulation of actin cytoskeleton;Chemokine signaling pathway
26231,90,0,0,0,0,18,0,1,21,0,0,518,LRRC29;leucine rich repeat containing 29,-,-,-,-
26232,0,0,1,3,13,0,22,0,0,0,7,0,FBXO2;F-box protein 2,GO:0043197//dendritic spine;GO:0019005//SCF ubiquitin ligase complex;GO:0031090//organelle membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0006516//glycoprotein catabolic process;GO:0006464//cellular protein modification process;GO:0031396//regulation of protein ubiquitination;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006508//proteolysis;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,GO:0001540//beta-amyloid binding;GO:0001948//glycoprotein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0030246//carbohydrate binding,K10099//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis
26233,4,0,0,0,0,29,54,50,0,0,22,0,FBXL6;F-box and leucine-rich repeat protein 6,-,GO:0006508//proteolysis;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity,-
26234,0,66,0,42,101,0,24,53,37,0,0,0,FBXL5;F-box and leucine-rich repeat protein 5,GO:0048471//perinuclear region of cytoplasm;GO:0000151//ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex,GO:0055072//iron ion homeostasis;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0004842//ubiquitin-protein transferase activity,-
26235,0,0,0,9,28,46,36,2,53,0,13,334,FBXL4;F-box and leucine-rich repeat protein 4,GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0005758//mitochondrial intermembrane space;GO:0005730//nucleolus,GO:0006511//ubiquitin-dependent protein catabolic process,-,-
26239,0,0,0,0,0,0,0,0,20,0,0,0,LCE2B;late cornified envelope 2B,-,GO:0008544//epidermis development;GO:0031424//keratinization,-,-
2624,69,129,0,1,94,21,54,53,4,7,2,0,GATA2;GATA binding protein 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0021533//cell differentiation in hindbrain;GO:0048873//homeostasis of number of cells within a tissue;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045599//negative regulation of fat cell differentiation;GO:0048469//cell maturation;GO:0045766//positive regulation of angiogenesis;GO:0042472//inner ear morphogenesis;GO:0021983//pituitary gland development;GO:0035854//eosinophil fate commitment;GO:0070345//negative regulation of fat cell proliferation;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0001709//cell fate determination;GO:0045650//negative regulation of macrophage differentiation;GO:0007596//blood coagulation;GO:0045746//negative regulation of Notch signaling pathway;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0060216//definitive hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021954//central nervous system neuron development;GO:0006909//phagocytosis;GO:0050766//positive regulation of phagocytosis;GO:0060872//semicircular canal development;GO:0035019//somatic stem cell maintenance;GO:0021514//ventral spinal cord interneuron differentiation;GO:0001892//embryonic placenta development;GO:0035065//regulation of histone acetylation;GO:0001655//urogenital system development",GO:0003682//chromatin binding;GO:0070742//C2H2 zinc finger domain binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
26240,0,0,0,0,10,0,0,0,13,0,0,0,"FAM50B;family with sequence similarity 50, member B",GO:0005634//nucleus,-,-,-
26245,92,0,0,0,0,0,0,0,0,0,0,0,"OR2M4;olfactory receptor, family 2, subfamily M, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26247,0,0,0,0,0,0,13,0,18,0,0,0,"OR2L1P;olfactory receptor, family 2, subfamily L, member 1 pseudogene",-,-,-,K04257//Olfactory transduction
26248,0,0,0,0,0,11,0,0,9,0,0,0,"OR2K2;olfactory receptor, family 2, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26249,0,0,0,0,1,9,23,136,14,0,9,0,KLHL3;kelch-like family member 3,GO:0005856//cytoskeleton;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005829//cytosol,GO:0050801//ion homeostasis;GO:0070294//renal sodium ion absorption;GO:0016567//protein ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0072156//distal tubule morphogenesis,GO:0003779//actin binding;GO:0005515//protein binding;GO:0005198//structural molecule activity,-
2625,0,0,0,0,6,25,0,0,20,0,0,0,GATA3;GATA binding protein 3,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0009615//response to virus;GO:0003215//cardiac right ventricle morphogenesis;GO:0001823//mesonephros development;GO:0060676//ureteric bud formation;GO:0035799//ureter maturation;GO:0032689//negative regulation of interferon-gamma production;GO:0048469//cell maturation;GO:0072602//interleukin-4 secretion;GO:0032736//positive regulation of interleukin-13 production;GO:0032703//negative regulation of interleukin-2 production;GO:0045087//innate immune response;GO:0006952//defense response;GO:0072179//nephric duct formation;GO:2000114//regulation of establishment of cell polarity;GO:0008584//male gonad development;GO:2000734//negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation;GO:0071599//otic vesicle development;GO:0035162//embryonic hemopoiesis;GO:0007596//blood coagulation;GO:0001764//neuron migration;GO:0072643//interferon-gamma secretion;GO:0009791//post-embryonic development;GO:0045471//response to ethanol;GO:2000667//positive regulation of interleukin-13 secretion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060231//mesenchymal to epithelial transition;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0009967//positive regulation of signal transduction;GO:0030218//erythrocyte differentiation;GO:0042493//response to drug;GO:2000611//positive regulation of thyroid hormone generation;GO:2000664//positive regulation of interleukin-5 secretion;GO:0051569//regulation of histone H3-K4 methylation;GO:0043627//response to estrogen;GO:0050728//negative regulation of inflammatory response;GO:0006366//transcription from RNA polymerase II promoter;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0007165//signal transduction;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0060017//parathyroid gland development;GO:0045061//thymic T cell selection;GO:0045582//positive regulation of T cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000146//negative regulation of cell motility;GO:0008285//negative regulation of cell proliferation;GO:0010595//positive regulation of endothelial cell migration;GO:0031929//TOR signaling;GO:0002088//lens development in camera-type eye;GO:0045064//T-helper 2 cell differentiation;GO:0001822//kidney development;GO:0042035//regulation of cytokine biosynthetic process;GO:0035457//cellular response to interferon-alpha;GO:0042472//inner ear morphogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0050852//T cell receptor signaling pathway;GO:0001709//cell fate determination;GO:0072107//positive regulation of ureteric bud formation;GO:0072182//regulation of nephron tubule epithelial cell differentiation;GO:0010975//regulation of neuron projection development;GO:0048589//developmental growth;GO:0071356//cellular response to tumor necrosis factor;GO:0045786//negative regulation of cell cycle;GO:0071353//cellular response to interleukin-4;GO:0003180//aortic valve morphogenesis;GO:0060374//mast cell differentiation;GO:0072676//lymphocyte migration;GO:2000683//regulation of cellular response to X-ray;GO:0007411//axon guidance;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0045599//negative regulation of fat cell differentiation;GO:2000703//negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation;GO:2000607//negative regulation of cell proliferation involved in mesonephros development;GO:0043583//ear development;GO:0009653//anatomical structure morphogenesis;GO:0010332//response to gamma radiation;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0043523//regulation of neuron apoptotic process;GO:0071773//cellular response to BMP stimulus;GO:0032754//positive regulation of interleukin-5 production;GO:0048485//sympathetic nervous system development;GO:0060065//uterus development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032753//positive regulation of interleukin-4 production;GO:0048538//thymus development;GO:0060037//pharyngeal system development;GO:0001701//in utero embryonic development;GO:0002572//pro-T cell differentiation;GO:0061290//canonical Wnt signaling pathway involved in metanephric kidney development;GO:0042421//norepinephrine biosynthetic process;GO:0006959//humoral immune response;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035898//parathyroid hormone secretion;GO:0003281//ventricular septum development",GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0071837//HMG box domain binding;GO:0003677//DNA binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0070888//E-box binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity,-
26251,0,0,0,0,0,13,0,0,14,0,0,0,"KCNG2;potassium voltage-gated channel, subfamily G, member 2",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0008076//voltage-gated potassium channel complex,GO:0044281//small molecule metabolic process;GO:0051260//protein homooligomerization;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0006813//potassium ion transport;GO:0008016//regulation of heart contraction,GO:0005251//delayed rectifier potassium channel activity,-
26253,0,0,0,0,0,0,0,0,13,0,0,0,"CLEC4E;C-type lectin domain family 4, member E",GO:0016021//integral component of membrane,GO:0006955//immune response;GO:0050715//positive regulation of cytokine secretion,GO:0030246//carbohydrate binding;GO:0004872//receptor activity,K10059//Tuberculosis
26254,0,0,0,0,0,0,18,0,2,0,27,0,OPTC;opticin,GO:0005578//proteinaceous extracellular matrix,GO:0016525//negative regulation of angiogenesis,GO:0005201//extracellular matrix structural constituent,-
26255,0,0,0,0,0,0,0,0,11,0,0,0,"PTTG3P;pituitary tumor-transforming 3, pseudogene",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051276//chromosome organization,GO:0017124//SH3 domain binding,K06635//HTLV-I infection;Oocyte meiosis;Cell cycle
26256,0,13,0,0,18,0,0,0,10,0,0,0,CABYR;calcium binding tyrosine-(Y)-phosphorylation regulated,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0035686//sperm fibrous sheath;GO:0031514//motile cilium,GO:0003351//epithelial cilium movement;GO:0048240//sperm capacitation,GO:0019899//enzyme binding;GO:0017124//SH3 domain binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity,-
26257,0,0,0,0,0,0,0,0,8,0,0,0,NKX2-8;NK2 homeobox 8,GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0030324//lung development;GO:0007409//axonogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001889//liver development",GO:0003690//double-stranded DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
26258,0,238,0,208,431,0,0,0,0,5,74,0,"BLOC1S6;biogenesis of lysosomal organelles complex-1, subunit 6, pallidin",GO:0031201//SNARE complex;GO:0005768//endosome;GO:0005829//cytosol;GO:0031083//BLOC-1 complex;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0019898//extrinsic component of membrane,GO:0061024//membrane organization;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0050942//positive regulation of pigment cell differentiation;GO:0032816//positive regulation of natural killer cell activation;GO:0061025//membrane fusion;GO:0035646//endosome to melanosome transport;GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0007596//blood coagulation;GO:0006892//post-Golgi vesicle-mediated transport;GO:0008089//anterograde axon cargo transport;GO:0032402//melanosome transport;GO:0030318//melanocyte differentiation;GO:0031175//neuron projection development;GO:0033299//secretion of lysosomal enzymes,GO:0019905//syntaxin binding;GO:0051015//actin filament binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
26259,0,0,1,8,16,0,83,1,0,0,0,0,FBXW8;F-box and WD repeat domain containing 8,GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm;GO:0019005//SCF ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex,GO:0050775//positive regulation of dendrite morphogenesis;GO:0008283//cell proliferation;GO:0060716//labyrinthine layer blood vessel development;GO:0016567//protein ubiquitination;GO:0007030//Golgi organization;GO:0060712//spongiotrophoblast layer development,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10264//Ubiquitin mediated proteolysis
2626,0,0,0,0,0,23,14,34,7,0,9,0,GATA4;GATA binding protein 4,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0007492//endoderm development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0001947//heart looping;GO:0001706//endoderm formation;GO:0060070//canonical Wnt signaling pathway;GO:0048557//embryonic digestive tract morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0003229//ventricular cardiac muscle tissue development;GO:0001701//in utero embryonic development;GO:0042493//response to drug;GO:0007267//cell-cell signaling;GO:0060395//SMAD protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045766//positive regulation of angiogenesis;GO:0010507//negative regulation of autophagy;GO:0043627//response to estrogen;GO:0006366//transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0003290//atrial septum secundum morphogenesis;GO:0003208//cardiac ventricle morphogenesis;GO:0003281//ventricular septum development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003215//cardiac right ventricle morphogenesis;GO:0003197//endocardial cushion development;GO:0072520//seminiferous tubule development;GO:0030509//BMP signaling pathway;GO:0086004//regulation of cardiac muscle cell contraction;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0051891//positive regulation of cardioblast differentiation;GO:0071333//cellular response to glucose stimulus;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:0060575//intestinal epithelial cell differentiation;GO:0007596//blood coagulation;GO:0003289//atrial septum primum morphogenesis;GO:0060008//Sertoli cell differentiation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0001702//gastrulation with mouth forming second;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0003181//atrioventricular valve morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0072148//epithelial cell fate commitment;GO:0048617//embryonic foregut morphogenesis",GO:0003682//chromatin binding;GO:0051525//NFAT protein binding;GO:0003677//DNA binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0070410//co-SMAD binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0033613//activating transcription factor binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
26260,0,0,46,65,68,0,16,0,20,0,0,154,FBXO25;F-box protein 25,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0019005//SCF ubiquitin ligase complex;GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination,GO:0003779//actin binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
26261,0,0,0,0,0,0,17,0,21,0,0,0,FBXO24;F-box protein 24,GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
26262,0,0,0,0,8,0,0,0,22,0,0,0,TSPAN17;tetraspanin 17,GO:0016021//integral component of membrane;GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0072594//establishment of protein localization to organelle,GO:0004842//ubiquitin-protein transferase activity;GO:0019899//enzyme binding,-
26263,0,0,29,38,169,17,0,0,6,0,41,0,FBXO22;F-box protein 22,GO:0030018//Z disc;GO:0005634//nucleus,GO:0000209//protein polyubiquitination;GO:0009267//cellular response to starvation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048742//regulation of skeletal muscle fiber development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006913//nucleocytoplasmic transport;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process,GO:0004842//ubiquitin-protein transferase activity,-
26266,0,76,100,0,46,1,0,86,24,0,8,0,"SLC13A4;solute carrier family 13 (sodium/sulfate symporter), member 4",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0008272//sulfate transport,GO:0015382//sodium:sulfate symporter activity,-
26267,200,0,12,30,7,0,21,0,49,284,27,0,FBXO10;F-box protein 10,GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0006915//apoptotic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
26268,91,0,1,25,137,7,11,36,0,0,0,0,FBXO9;F-box protein 9,GO:0000151//ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032006//regulation of TOR signaling;GO:0016567//protein ubiquitination;GO:0045087//innate immune response;GO:0045444//fat cell differentiation,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
26269,0,33,58,61,98,3,0,0,71,0,108,0,FBXO8;F-box protein 8,GO:0030054//cell junction;GO:0005802//trans-Golgi network;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization;GO:0032012//regulation of ARF protein signal transduction,GO:0005086//ARF guanyl-nucleotide exchange factor activity,-
2627,0,0,0,0,29,0,26,0,11,0,2,0,GATA6;GATA binding protein 6,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0043066//negative regulation of apoptotic process;GO:0001889//liver development;GO:0071158//positive regulation of cell cycle arrest;GO:0060430//lung saccule development;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060510//Type II pneumocyte differentiation;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0060486//Clara cell differentiation;GO:0051891//positive regulation of cardioblast differentiation;GO:0008584//male gonad development;GO:0048645//organ formation;GO:0032912//negative regulation of transforming growth factor beta2 production;GO:0060575//intestinal epithelial cell differentiation;GO:0007596//blood coagulation;GO:0051145//smooth muscle cell differentiation;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0003310//pancreatic A cell differentiation;GO:0071773//cellular response to BMP stimulus;GO:0071456//cellular response to hypoxia;GO:0003309//type B pancreatic cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0042493//response to drug;GO:0001701//in utero embryonic development;GO:0070848//response to growth factor;GO:0043627//response to estrogen;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0055007//cardiac muscle cell differentiation;GO:0071371//cellular response to gonadotropin stimulus;GO:0006644//phospholipid metabolic process;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0035239//tube morphogenesis",GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0019901//protein kinase binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003682//chromatin binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding,-
26270,0,19,0,0,0,0,0,0,0,0,0,0,FBXO6;F-box protein 6,GO:0019005//SCF ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0006516//glycoprotein catabolic process;GO:0000077//DNA damage checkpoint;GO:0006986//response to unfolded protein;GO:0006508//proteolysis;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0030246//carbohydrate binding;GO:0001948//glycoprotein binding,K10100//Protein processing in endoplasmic reticulum
26271,0,0,0,0,13,15,61,0,13,0,0,0,FBXO5;F-box protein 5,GO:0005654//nucleoplasm;GO:0005819//spindle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0007057//spindle assembly involved in female meiosis I;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0001556//oocyte maturation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0016050//vesicle organization;GO:0000278//mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0046785//microtubule polymerization;GO:0007346//regulation of mitotic cell cycle;GO:0045835//negative regulation of meiosis;GO:0060565//inhibition of mitotic anaphase-promoting complex activity,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,K10292//Oocyte meiosis
26272,0,0,0,0,0,0,0,0,30,0,0,0,FBXO4;F-box protein 4,GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex,GO:0000209//protein polyubiquitination;GO:0000723//telomere maintenance;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042803//protein homodimerization activity,K10291//Ubiquitin mediated proteolysis
26273,0,0,0,28,63,19,0,0,37,0,0,0,FBXO3;F-box protein 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006508//proteolysis;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
26275,0,0,1,22,26,0,0,0,0,0,0,0,HIBCH;3-hydroxyisobutyryl-CoA hydrolase,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006574//valine catabolic process;GO:0009083//branched-chain amino acid catabolic process,GO:0003860//3-hydroxyisobutyryl-CoA hydrolase activity,"K05605//Propanoate metabolism;beta-Alanine metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation"
26276,0,0,0,0,2,0,1,0,5,0,7,0,VPS33B;vacuolar protein sorting 33 homolog B (yeast),GO:0005770//late endosome;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0031091//platelet alpha granule;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0031902//late endosome membrane,GO:0016192//vesicle-mediated transport;GO:0061025//membrane fusion;GO:0006904//vesicle docking involved in exocytosis;GO:0032400//melanosome localization;GO:0015031//protein transport;GO:0070889//platelet alpha granule organization;GO:0032418//lysosome localization,GO:0005515//protein binding,K15292//Synaptic vesicle cycle
26277,0,78,140,36,78,0,0,56,28,0,0,0,TINF2;TERF1 (TRF1)-interacting nuclear factor 2,"GO:0010370//perinucleolar chromocenter;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex","GO:0050680//negative regulation of epithelial cell proliferation;GO:0010836//negative regulation of protein ADP-ribosylation;GO:0010833//telomere maintenance via telomere lengthening;GO:0070198//protein localization to chromosome, telomeric region;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0034502//protein localization to chromosome;GO:0032206//positive regulation of telomere maintenance;GO:0000723//telomere maintenance;GO:0032202//telomere assembly",GO:0042162//telomeric DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
26278,45,0,0,5,23,14,59,110,47,0,0,0,SACS;sacsin molecular chaperone,GO:0005739//mitochondrion;GO:0070852//cell body fiber;GO:0030424//axon;GO:0030425//dendrite;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006457//protein folding;GO:0008219//cell death;GO:0090084//negative regulation of inclusion body assembly,GO:0030544//Hsp70 protein binding;GO:0051087//chaperone binding;GO:0070628//proteasome binding,-
26279,0,0,0,0,0,0,0,0,3,0,11,0,"PLA2G2D;phospholipase A2, group IID",GO:0005576//extracellular region,GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process,GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity,K01047//Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Long-term depression;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;GnRH signaling pathway;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Metabolic pathways;Vascular smooth muscle contraction
2628,0,24,0,0,8,0,0,0,2,0,0,0,GATM;glycine amidinotransferase (L-arginine:glycine amidinotransferase),GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome,GO:0006601//creatine biosynthetic process;GO:0009790//embryo development;GO:0042246//tissue regeneration;GO:0044281//small molecule metabolic process;GO:0046689//response to mercury ion;GO:0007584//response to nutrient;GO:0006600//creatine metabolic process;GO:0006979//response to oxidative stress;GO:0034641//cellular nitrogen compound metabolic process;GO:0043434//response to peptide hormone,"GO:0016813//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines;GO:0015068//glycine amidinotransferase activity","K00613//Metabolic pathways;Arginine and proline metabolism;Glycine, serine and threonine metabolism"
26280,0,0,0,0,0,11,31,0,12,0,0,0,IL1RAPL2;interleukin 1 receptor accessory protein-like 2,GO:0016021//integral component of membrane,GO:0007417//central nervous system development;GO:0019221//cytokine-mediated signaling pathway,"GO:0004908//interleukin-1 receptor activity;GO:0004910//interleukin-1, Type II, blocking receptor activity",-
26284,0,13,0,7,6,38,0,0,22,0,1,0,ERAL1;Era-like 12S mitochondrial rRNA chaperone 1,GO:0005743//mitochondrial inner membrane;GO:0045111//intermediate filament cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0000028//ribosomal small subunit assembly,GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0019843//rRNA binding;GO:0044822//poly(A) RNA binding,-
26286,0,88,1,88,405,0,0,0,0,0,2,25,ARFGAP3;ADP-ribosylation factor GTPase activating protein 3,GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm,GO:0016192//vesicle-mediated transport;GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity;GO:0006886//intracellular protein transport;GO:0009306//protein secretion,GO:0008565//protein transporter activity;GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding,K12493//Endocytosis
26287,0,0,0,0,0,0,2,0,6,28,13,0,ANKRD2;ankyrin repeat domain 2 (stretch responsive muscle),GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0016605//PML body;GO:0031674//I band;GO:0000791//euchromatin;GO:0005634//nucleus,GO:0007517//muscle organ development;GO:0006936//muscle contraction;GO:0045662//negative regulation of myoblast differentiation;GO:0035914//skeletal muscle cell differentiation,GO:0008307//structural constituent of muscle;GO:0043422//protein kinase B binding;GO:0031432//titin binding,-
26289,56,0,0,0,3,27,0,0,31,0,8,0,AK5;adenylate kinase 5,GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006172//ADP biosynthetic process;GO:0046034//ATP metabolic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0044281//small molecule metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006173//dADP biosynthetic process;GO:0009220//pyrimidine ribonucleotide biosynthetic process,GO:0019206//nucleoside kinase activity;GO:0004017//adenylate kinase activity;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
2629,0,0,0,0,0,10,0,2,37,0,0,382,"GBA;glucosidase, beta, acid",GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane,GO:0033574//response to testosterone;GO:0035307//positive regulation of protein dephosphorylation;GO:0033561//regulation of water loss via skin;GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0009268//response to pH;GO:0008219//cell death;GO:0006680//glucosylceramide catabolic process;GO:0043627//response to estrogen;GO:0006687//glycosphingolipid metabolic process;GO:0050728//negative regulation of inflammatory response;GO:0043589//skin morphogenesis;GO:0043407//negative regulation of MAP kinase activity;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process;GO:0097066//response to thyroid hormone;GO:0071356//cellular response to tumor necrosis factor;GO:0046512//sphingosine biosynthetic process;GO:0032715//negative regulation of interleukin-6 production;GO:0005975//carbohydrate metabolic process;GO:0023021//termination of signal transduction,GO:0005515//protein binding;GO:0004348//glucosylceramidase activity;GO:0005102//receptor binding,K01201//Sphingolipid metabolism;Lysosome;Other glycan degradation;Metabolic pathways
26290,100,0,0,0,0,0,7,26,14,0,0,0,GALNT8;polypeptide N-acetylgalactosaminyltransferase 8,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
26291,36,0,0,0,0,0,0,0,17,0,0,0,FGF21;fibroblast growth factor 21,GO:0005576//extracellular region,GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0007165//signal transduction;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0046326//positive regulation of glucose import,GO:0005104//fibroblast growth factor receptor binding;GO:0005515//protein binding;GO:0008083//growth factor activity,K04358//MAPK signaling pathway;Pathways in cancer;Melanoma;Regulation of actin cytoskeleton
26297,0,0,0,0,1,0,0,0,8,0,0,444,SERGEF;secretion regulating guanine nucleotide exchange factor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus,GO:0050709//negative regulation of protein secretion;GO:0007165//signal transduction;GO:0032853//positive regulation of Ran GTPase activity,GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K00502//Metabolic pathways;Tryptophan metabolism;Serotonergic synapse
26298,0,283,2,493,1407,8,0,0,59,50,0,0,EHF;ets homologous factor,GO:0005634//nucleus,"GO:0030855//epithelial cell differentiation;GO:0007275//multicellular organismal development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2630,111,0,0,0,0,11,0,0,31,0,0,0,"GBAP1;glucosidase, beta, acid pseudogene 1",-,-,-,K01201//Sphingolipid metabolism;Lysosome;Other glycan degradation;Metabolic pathways
26301,0,0,0,0,0,0,0,0,3,0,0,0,"GBGT1;globoside alpha-1,3-N-acetylgalactosaminyltransferase 1",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation;GO:0009247//glycolipid biosynthetic process,GO:0046872//metal ion binding;GO:0047277//globoside alpha-N-acetylgalactosaminyltransferase activity,K00722//Metabolic pathways;Glycosphingolipid biosynthesis - globo series
2631,0,20,1,72,104,0,0,0,38,37,0,0,GBAS;glioblastoma amplified sequence,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005887//integral component of plasma membrane,GO:2000984//negative regulation of ATP citrate synthase activity;GO:0006754//ATP biosynthetic process;GO:0006119//oxidative phosphorylation,GO:0005515//protein binding,-
2632,0,1,0,6,76,32,0,16,53,0,0,0,"GBE1;glucan (1,4-alpha-), branching enzyme 1",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0005978//glycogen biosynthetic process;GO:0005977//glycogen metabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy,"GO:0043169//cation binding;GO:0003844//1,4-alpha-glucan branching enzyme activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",K00700//Starch and sucrose metabolism;Metabolic pathways
2633,0,0,0,0,9,0,0,0,73,0,0,0,"GBP1;guanylate binding protein 1, interferon-inducible",GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0005576//extracellular region,GO:0051607//defense response to virus;GO:0006184//GTP catabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0042802//identical protein binding,-
26330,0,23,38,29,61,0,32,78,33,1,134,0,"GAPDHS;glyceraldehyde-3-phosphate dehydrogenase, spermatogenic",GO:0005829//cytosol;GO:0035686//sperm fibrous sheath;GO:0097228//sperm principal piece;GO:0005634//nucleus,GO:0007286//spermatid development;GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0006094//gluconeogenesis;GO:0045821//positive regulation of glycolytic process;GO:0030317//sperm motility,GO:0005515//protein binding;GO:0051287//NAD binding;GO:0050661//NADP binding;GO:0004365//glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity,K10705//Metabolic pathways;Glycolysis / Gluconeogenesis
26333,0,0,0,0,0,0,0,0,11,0,0,0,"OR7A17;olfactory receptor, family 7, subfamily A, member 17",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26338,0,0,0,0,0,0,0,0,8,0,0,0,"OR5L2;olfactory receptor, family 5, subfamily L, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2634,0,0,0,7,3,17,0,0,21,0,0,200,"GBP2;guanylate binding protein 2, interferon-inducible",GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005634//nucleus,GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006184//GTP catabolic process;GO:0006955//immune response;GO:0060337//type I interferon signaling pathway,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
26341,0,0,0,0,0,0,0,0,19,0,0,0,"OR5H1;olfactory receptor, family 5, subfamily H, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2635,0,0,0,11,0,0,0,109,18,1,20,1,GBP3;guanylate binding protein 3,GO:0005737//cytoplasm;GO:0016020//membrane,GO:0006184//GTP catabolic process;GO:0051607//defense response to virus,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding,-
26353,0,1,0,0,14,0,18,0,0,0,0,0,HSPB8;heat shock 22kDa protein 8,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005622//intracellular,GO:0008219//cell death;GO:0006950//response to stress,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0004672//protein kinase activity,-
26354,0,93,2,39,123,7,0,0,0,0,0,0,GNL3;guanine nucleotide binding protein-like 3 (nucleolar),GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0016020//membrane,GO:0042127//regulation of cell proliferation;GO:0008283//cell proliferation;GO:0006184//GTP catabolic process;GO:0042254//ribosome biogenesis,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14538//Ribosome biogenesis in eukaryotes
26355,0,146,0,53,87,0,10,0,36,0,0,0,"FAM162A;family with sequence similarity 162, member A",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051402//neuron apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0071456//cellular response to hypoxia;GO:0043065//positive regulation of apoptotic process;GO:0006927//transformed cell apoptotic process,GO:0005515//protein binding,-
2636,0,0,0,0,0,0,0,0,0,0,2,0,GBX1;gastrulation brain homeobox 1,GO:0005634//nucleus,"GO:0097374//sensory neuron axon guidance;GO:0007628//adult walking behavior;GO:0006355//regulation of transcription, DNA-templated;GO:0019230//proprioception;GO:0021522//spinal cord motor neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0048663//neuron fate commitment",GO:0043565//sequence-specific DNA binding,-
2638,0,0,0,0,0,0,20,0,32,0,0,0,GC;group-specific component (vitamin D binding protein),GO:0043202//lysosomal lumen;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region,GO:0042359//vitamin D metabolic process;GO:0008202//steroid metabolic process;GO:0051180//vitamin transport;GO:0044281//small molecule metabolic process,GO:1902118//calcidiol binding;GO:0005499//vitamin D binding;GO:0003779//actin binding;GO:0051183//vitamin transporter activity,-
2639,0,0,0,0,5,0,0,0,56,150,14,0,GCDH;glutaryl-CoA dehydrogenase,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0019395//fatty acid oxidation;GO:0046949//fatty-acyl-CoA biosynthetic process;GO:0006568//tryptophan metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006554//lysine catabolic process;GO:0044281//small molecule metabolic process,GO:0000062//fatty-acyl-CoA binding;GO:0004361//glutaryl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding,K00252//Tryptophan metabolism;Fatty acid metabolism;Lysine degradation;Microbial metabolism in diverse environments;Metabolic pathways;Benzoate degradation
2641,0,0,0,0,0,0,0,0,21,0,0,0,GCG;glucagon,GO:0005788//endoplasmic reticulum lumen;GO:0034774//secretory granule lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0090280//positive regulation of calcium ion import;GO:1900118//negative regulation of execution phase of apoptosis;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007631//feeding behavior;GO:0006112//energy reserve metabolic process;GO:0044267//cellular protein metabolic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045722//positive regulation of gluconeogenesis;GO:0010737//protein kinase A signaling;GO:0045860//positive regulation of protein kinase activity;GO:0007165//signal transduction;GO:0042594//response to starvation;GO:0008283//cell proliferation;GO:0032092//positive regulation of protein binding;GO:0050796//regulation of insulin secretion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0071377//cellular response to glucagon stimulus;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0031769//glucagon receptor binding;GO:0005179//hormone activity;GO:0005102//receptor binding,-
2642,0,0,0,0,0,1,0,65,16,144,0,0,GCGR;glucagon receptor,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005768//endosome,GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0006112//energy reserve metabolic process;GO:0042594//response to starvation;GO:0006887//exocytosis;GO:0007584//response to nutrient;GO:0006091//generation of precursor metabolites and energy;GO:0043547//positive regulation of GTPase activity;GO:0044281//small molecule metabolic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0042593//glucose homeostasis;GO:0070873//regulation of glycogen metabolic process,GO:0017046//peptide hormone binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0004967//glucagon receptor activity,K04583//Neuroactive ligand-receptor interaction
2643,77,0,0,0,0,0,21,0,0,0,0,0,GCH1;GTP cyclohydrolase 1,GO:0031965//nuclear membrane;GO:0043234//protein complex;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0035998//7,8-dihydroneopterin 3'-triphosphate biosynthetic process;GO:0051291//protein heterooligomerization;GO:0048265//response to pain;GO:0046654//tetrahydrofolate biosynthetic process;GO:0034341//response to interferon-gamma;GO:0034612//response to tumor necrosis factor;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0042311//vasodilation;GO:0008217//regulation of blood pressure;GO:0042416//dopamine biosynthetic process;GO:0045776//negative regulation of blood pressure;GO:0046209//nitric oxide metabolic process;GO:0008152//metabolic process;GO:0014916//regulation of lung blood pressure;GO:0032496//response to lipopolysaccharide;GO:0006809//nitric oxide biosynthetic process;GO:0006184//GTP catabolic process;GO:0050884//neuromuscular process controlling posture;GO:0044281//small molecule metabolic process;GO:0051260//protein homooligomerization",GO:0005525//GTP binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding;GO:0003934//GTP cyclohydrolase I activity;GO:0050662//coenzyme binding,"K01495//Metabolic pathways;Alanine, aspartate and glutamate metabolism;Two-component system;Glyoxylate and dicarboxylate metabolism;Fatty acid biosynthesis;Nitrogen metabolism;Arginine and proline metabolism;Microbial metabolism in diverse environments;Folate biosynthesis"
2644,83,77,0,31,56,0,0,0,66,0,98,0,GCHFR;GTP cyclohydrolase I feedback regulator,GO:0031965//nuclear membrane;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0042470//melanosome;GO:0030425//dendrite,GO:0009890//negative regulation of biosynthetic process;GO:0046209//nitric oxide metabolic process;GO:0051291//protein heterooligomerization;GO:0043105//negative regulation of GTP cyclohydrolase I activity;GO:0006809//nitric oxide biosynthetic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0044281//small molecule metabolic process;GO:0042133//neurotransmitter metabolic process,GO:0044549//GTP cyclohydrolase binding;GO:0016597//amino acid binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding,-
2645,0,0,0,0,0,9,14,0,0,0,0,268,GCK;glucokinase (hexokinase 4),GO:0005654//nucleoplasm;GO:0005938//cell cortex;GO:0030141//secretory granule;GO:0005829//cytosol;GO:0005739//mitochondrion,"GO:0042327//positive regulation of phosphorylation;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0042593//glucose homeostasis;GO:0051594//detection of glucose;GO:0070509//calcium ion import;GO:0032811//negative regulation of epinephrine secretion;GO:0051156//glucose 6-phosphate metabolic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043266//regulation of potassium ion transport;GO:0045821//positive regulation of glycolytic process;GO:0055085//transmembrane transport;GO:0042149//cellular response to glucose starvation;GO:0015758//glucose transport;GO:0032869//cellular response to insulin stimulus;GO:0050796//regulation of insulin secretion;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006739//NADP metabolic process;GO:0005975//carbohydrate metabolic process;GO:0031018//endocrine pancreas development;GO:0001678//cellular glucose homeostasis;GO:0006110//regulation of glycolytic process;GO:0010827//regulation of glucose transport;GO:0032024//positive regulation of insulin secretion;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0044320//cellular response to leptin stimulus;GO:0045721//negative regulation of gluconeogenesis;GO:0019932//second-messenger-mediated signaling",GO:0005515//protein binding;GO:0043531//ADP binding;GO:0000287//magnesium ion binding;GO:0008865//fructokinase activity;GO:0019158//mannokinase activity;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0005536//glucose binding;GO:0004340//glucokinase activity,K12407//Butirosin and neomycin biosynthesis;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Glycolysis / Gluconeogenesis;Insulin signaling pathway;Type II diabetes mellitus;Maturity onset diabetes of the young;Galactose metabolism;Metabolic pathways
2646,145,0,0,0,0,17,0,1,27,0,2,0,GCKR;glucokinase (hexokinase 4) regulator,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol,"GO:0009750//response to fructose;GO:0070328//triglyceride homeostasis;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0001678//cellular glucose homeostasis;GO:0010827//regulation of glucose transport;GO:0000060//protein import into nucleus, translocation;GO:0055085//transmembrane transport;GO:0033133//positive regulation of glucokinase activity;GO:0015758//glucose transport;GO:0046415//urate metabolic process;GO:0033132//negative regulation of glucokinase activity",GO:0030246//carbohydrate binding;GO:0070095//fructose-6-phosphate binding;GO:0005515//protein binding;GO:0004857//enzyme inhibitor activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding,-
26468,0,0,0,0,8,18,40,0,82,0,18,0,LHX6;LIM homeobox 6,GO:0005634//nucleus,"GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0006355//regulation of transcription, DNA-templated;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021877//forebrain neuron fate commitment;GO:0021800//cerebral cortex tangential migration;GO:0048469//cell maturation;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
26469,0,5,0,0,68,8,0,21,1,0,13,0,"PTPN18;protein tyrosine phosphatase, non-receptor type 18 (brain-derived)",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0005515//protein binding,-
2647,0,0,0,0,0,0,0,0,22,0,3,0,"BLOC1S1;biogenesis of lysosomal organelles complex-1, subunit 1",GO:0031083//BLOC-1 complex;GO:0005759//mitochondrial matrix;GO:0005765//lysosomal membrane;GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0008089//anterograde axon cargo transport;GO:0031175//neuron projection development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0048490//anterograde synaptic vesicle transport;GO:0032438//melanosome organization;GO:0061024//membrane organization;GO:0018394//peptidyl-lysine acetylation;GO:0060155//platelet dense granule organization;GO:0009060//aerobic respiration,GO:0005515//protein binding,-
26470,0,0,0,0,0,40,10,0,17,0,24,284,SEZ6L2;seizure related 6 homolog (mouse)-like 2,GO:0005789//endoplasmic reticulum membrane;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008344//adult locomotory behavior;GO:0021680//cerebellar Purkinje cell layer development;GO:0090036//regulation of protein kinase C signaling;GO:0060074//synapse maturation,-,K04006//Complement and coagulation cascades;Hematopoietic cell lineage;Viral myocarditis;K04007//Complement and coagulation cascades;Measles
26471,116,37,2,20,54,0,0,0,0,0,1,0,"NUPR1;nuclear protein, transcriptional regulator, 1",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006461//protein complex assembly;GO:0016049//cell growth;GO:0045786//negative regulation of cell cycle;GO:0002526//acute inflammatory response;GO:0035914//skeletal muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0009636//response to toxic substance;GO:0031401//positive regulation of protein modification process;GO:0006351//transcription, DNA-templated;GO:0048147//negative regulation of fibroblast proliferation;GO:0043065//positive regulation of apoptotic process;GO:0006473//protein acetylation;GO:0008584//male gonad development",GO:0003682//chromatin binding;GO:0003677//DNA binding,K15626//Transcriptional misregulation in cancer
26472,0,0,0,0,0,0,0,1,0,0,0,0,"PPP1R14B;protein phosphatase 1, regulatory (inhibitor) subunit 14B",GO:0005737//cytoplasm,GO:0043086//negative regulation of catalytic activity;GO:0042325//regulation of phosphorylation,GO:0004864//protein phosphatase inhibitor activity,K05744//Axon guidance;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;K12328//Vascular smooth muscle contraction
26476,0,0,0,0,0,0,0,0,9,0,0,0,"OR10J1;olfactory receptor, family 10, subfamily J, member 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007606//sensory perception of chemical stimulus;GO:0007338//single fertilization;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2648,0,0,0,0,0,16,0,0,0,0,23,0,KAT2A;K(lysine) acetyltransferase 2A,GO:0033276//transcription factor TFTC complex;GO:0072686//mitotic spindle;GO:0005615//extracellular space;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0030914//STAGA complex;GO:0005654//nucleoplasm,GO:0001756//somitogenesis;GO:0001701//in utero embryonic development;GO:0022037//metencephalon development;GO:0031647//regulation of protein stability;GO:0006325//chromatin organization;GO:0035264//multicellular organism growth;GO:0008283//cell proliferation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0044154//histone H3-K14 acetylation;GO:0021537//telencephalon development;GO:0043983//histone H4-K12 acetylation;GO:0001843//neural tube closure;GO:0043966//histone H3 acetylation;GO:0030901//midbrain development;GO:0016032//viral process;GO:0016578//histone deubiquitination;GO:0045722//positive regulation of gluconeogenesis;GO:0006338//chromatin remodeling;GO:0006366//transcription from RNA polymerase II promoter,GO:0004402//histone acetyltransferase activity;GO:0010484//H3 histone acetyltransferase activity;GO:0043997//histone acetyltransferase activity (H4-K12 specific);GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding,K06062//Notch signaling pathway;HTLV-I infection
2649,0,0,0,0,0,13,23,0,39,0,0,420,"NR6A1;nuclear receptor subfamily 6, group A, member 1",GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007276//gamete generation;GO:0008283//cell proliferation;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0010467//gene expression,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0042803//protein homodimerization activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding,-
26493,0,0,0,0,0,0,0,0,31,0,0,0,"OR8B8;olfactory receptor, family 8, subfamily B, member 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26499,0,0,14,7,0,0,12,51,13,0,0,0,PLEK2;pleckstrin 2,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0031258//lamellipodium membrane,GO:0035556//intracellular signal transduction;GO:0030036//actin cytoskeleton organization,-,K07364//T cell receptor signaling pathway;Osteoclast differentiation;K12229//B cell receptor signaling pathway
265,0,0,0,0,0,12,0,0,58,0,0,0,"AMELX;amelogenin, X-linked",GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix,GO:0032967//positive regulation of collagen biosynthetic process;GO:0070172//positive regulation of tooth mineralization;GO:0008283//cell proliferation;GO:0002062//chondrocyte differentiation;GO:0007155//cell adhesion;GO:0042475//odontogenesis of dentin-containing tooth;GO:0034505//tooth mineralization;GO:0001649//osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0007165//signal transduction;GO:0031214//biomineral tissue development;GO:0070166//enamel mineralization;GO:0050801//ion homeostasis,GO:0030345//structural constituent of tooth enamel;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0046848//hydroxyapatite binding;GO:0008083//growth factor activity,-
2650,112,31,0,0,17,0,53,0,36,0,0,0,"GCNT1;glucosaminyl (N-acetyl) transferase 1, core 2",GO:0031985//Golgi cisterna;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0050901//leukocyte tethering or rolling;GO:0009101//glycoprotein biosynthetic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0060352//cell adhesion molecule production;GO:0032868//response to insulin;GO:0044267//cellular protein metabolic process;GO:0060993//kidney morphogenesis;GO:0048729//tissue morphogenesis,"GO:0005515//protein binding;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity",K00727//Mucin type O-Glycan biosynthesis;Metabolic pathways
26502,0,0,23,19,47,0,0,0,14,0,50,0,NARF;nuclear prelamin A recognition factor,GO:0005638//lamin filament;GO:0031981//nuclear lumen;GO:0005652//nuclear lamina;GO:0005634//nucleus,-,GO:0005521//lamin binding,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
26503,0,0,0,0,6,0,0,0,27,0,0,0,"SLC17A5;solute carrier family 17 (acidic sugar transporter), member 5",GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0015739//sialic acid transport;GO:0055085//transmembrane transport;GO:0015992//proton transport;GO:0006811//ion transport;GO:0006820//anion transport;GO:0006865//amino acid transport,GO:0015136//sialic acid transmembrane transporter activity;GO:0005351//sugar:proton symporter activity,K12301//Lysosome
26504,0,0,0,0,1,10,0,36,32,0,4,0,CNNM4;cyclin M4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0031214//biomineral tissue development;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0006811//ion transport,GO:0030554//adenyl nucleotide binding,-
26505,49,0,2,33,17,0,24,0,45,0,35,0,CNNM3;cyclin M3,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006811//ion transport,GO:0005515//protein binding;GO:0030554//adenyl nucleotide binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
26507,0,0,0,0,0,24,33,0,16,0,3,0,CNNM1;cyclin M1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006811//ion transport,GO:0030554//adenyl nucleotide binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
26508,78,0,0,0,0,3,6,0,44,0,3,0,HEYL;hes-related family bHLH transcription factor with YRPW motif-like,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006366//transcription from RNA polymerase II promoter;GO:0072014//proximal tubule development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003181//atrioventricular valve morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060412//ventricular septum morphogenesis;GO:0007219//Notch signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0003208//cardiac ventricle morphogenesis;GO:0014031//mesenchymal cell development;GO:0003184//pulmonary valve morphogenesis;GO:2000824//negative regulation of androgen receptor activity;GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0035914//skeletal muscle cell differentiation;GO:0032835//glomerulus development;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0071773//cellular response to BMP stimulus",GO:0008134//transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0050683//AF-1 domain binding;GO:0035939//microsatellite binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000988//protein binding transcription factor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003714//transcription corepressor activity,-
26509,0,54,0,34,492,12,33,62,82,0,0,0,MYOF;myoferlin,GO:0043231//intracellular membrane-bounded organelle;GO:0005901//caveola;GO:0005635//nuclear envelope;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0031965//nuclear membrane;GO:0031410//cytoplasmic vesicle,GO:0008015//blood circulation;GO:0006936//muscle contraction;GO:0034605//cellular response to heat;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001778//plasma membrane repair,GO:0005543//phospholipid binding;GO:0005515//protein binding,K02677//Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;Vascular smooth muscle contraction;Phototransduction - fly;Amoebiasis;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;African trypanosomiasis;Long-term potentiation;Carbohydrate digestion and absorption;Non-small cell lung cancer;Melanogenesis;Vibrio cholerae infection;Tight junction;GABAergic synapse;Cholinergic synapse;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Salivary secretion;MAPK signaling pathway;Morphine addiction;ErbB signaling pathway;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Dopaminergic synapse;Gap junction;NF-kappa B signaling pathway;Serotonergic synapse;Influenza A;Leishmaniasis;Glioma;Gastric acid secretion;Pathogenic Escherichia coli infection;Focal adhesion;VEGF signaling pathway;Long-term depression;Retrograde endocannabinoid signaling;Calcium signaling pathway;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Leukocyte transendothelial migration
2651,145,34,2,37,111,14,16,1,47,128,0,0,"GCNT2;glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006024//glycosaminoglycan biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0006486//protein glycosylation;GO:0051897//positive regulation of protein kinase B signaling;GO:0030335//positive regulation of cell migration;GO:0010812//negative regulation of cell-substrate adhesion;GO:0007275//multicellular organismal development;GO:0036438//maintenance of lens transparency;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0010608//posttranscriptional regulation of gene expression,"GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity",K00742//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
26511,0,0,0,13,0,0,0,0,17,0,0,0,CHIC2;cysteine-rich hydrophobic domain 2,GO:0005798//Golgi-associated vesicle;GO:0005886//plasma membrane,-,GO:0005515//protein binding,-
26512,0,23,3,21,169,41,0,213,44,17,0,0,INTS6;integrator complex subunit 6,GO:0015629//actin cytoskeleton;GO:0005730//nucleolus;GO:0032039//integrator complex;GO:0005634//nucleus,GO:0016180//snRNA processing;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,-
26515,83,85,1,53,243,0,34,0,12,0,1,0,TIMM10B;translocase of inner mitochondrial membrane 10 homolog B (yeast),GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0042719//mitochondrial intermembrane space protein transporter complex,GO:0044267//cellular protein metabolic process;GO:0007160//cell-matrix adhesion;GO:0006626//protein targeting to mitochondrion,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
26517,0,1,0,0,0,19,0,0,16,0,5,0,TIMM13;translocase of inner mitochondrial membrane 13 homolog (yeast),GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0042719//mitochondrial intermembrane space protein transporter complex,GO:0007605//sensory perception of sound;GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process;GO:0072321//chaperone-mediated protein transport,GO:0008270//zinc ion binding,-
26519,0,23,10,3,1,0,1,0,0,0,1,0,TIMM10;translocase of inner mitochondrial membrane 10 homolog (yeast),GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0042719//mitochondrial intermembrane space protein transporter complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space,GO:0007605//sensory perception of sound;GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process;GO:0072321//chaperone-mediated protein transport;GO:0045039//protein import into mitochondrial inner membrane,GO:0051087//chaperone binding;GO:0005215//transporter activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
2652,0,0,1,18,0,0,38,0,0,1,0,101,"OPN1MW;opsin 1 (cone pigments), medium-wave-sensitive",-,-,-,-
26520,0,0,9,16,23,12,0,0,22,0,9,0,TIMM9;translocase of inner mitochondrial membrane 9 homolog (yeast),GO:0042719//mitochondrial intermembrane space protein transporter complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space,GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0044267//cellular protein metabolic process;GO:0072321//chaperone-mediated protein transport;GO:0045039//protein import into mitochondrial inner membrane,GO:0005215//transporter activity;GO:0051087//chaperone binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K11600//RNA degradation
26521,47,0,1,10,18,13,0,0,0,143,20,0,TIMM8B;translocase of inner mitochondrial membrane 8 homolog B (yeast),GO:0005743//mitochondrial inner membrane;GO:0005615//extracellular space;GO:0042719//mitochondrial intermembrane space protein transporter complex,GO:0006626//protein targeting to mitochondrion;GO:0007605//sensory perception of sound;GO:0044267//cellular protein metabolic process;GO:0072321//chaperone-mediated protein transport,GO:0008270//zinc ion binding,-
26523,203,29,2,50,206,4,0,29,73,0,16,65,AGO1;argonaute RISC catalytic component 1,GO:0000932//cytoplasmic mRNA processing body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex;GO:0035068//micro-ribonucleoprotein complex;GO:0005844//polysome,"GO:0006351//transcription, DNA-templated;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0010467//gene expression;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0007219//Notch signaling pathway",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004521//endoribonuclease activity;GO:0003723//RNA binding,-
26524,0,0,0,1,10,0,9,69,4,0,4,0,LATS2;large tumor suppressor kinase 2,GO:0005634//nucleus;GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0005829//cytosol,GO:0000082//G1/S transition of mitotic cell cycle;GO:0009755//hormone-mediated signaling pathway;GO:0007067//mitotic nuclear division;GO:0034613//cellular protein localization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0030216//keratinocyte differentiation;GO:0035556//intracellular signal transduction;GO:0035329//hippo signaling;GO:0006468//protein phosphorylation;GO:0046620//regulation of organ growth,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
26525,0,0,0,0,0,0,0,10,7,0,0,0,IL36RN;interleukin 36 receptor antagonist,GO:0005615//extracellular space,GO:0032715//negative regulation of interleukin-6 production;GO:0032700//negative regulation of interleukin-17 production;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0019732//antifungal humoral response,GO:0005149//interleukin-1 receptor binding;GO:0005125//cytokine activity;GO:0005152//interleukin-1 receptor antagonist activity,-
26528,1,0,0,4,16,0,13,0,11,0,1,276,DAZAP1;DAZ associated protein 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0001893//maternal placenta development;GO:0008283//cell proliferation;GO:0030154//cell differentiation,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0035613//RNA stem-loop binding;GO:0003723//RNA binding,K14411//mRNA surveillance pathway
26529,0,0,0,0,0,0,0,0,29,0,0,0,"OR12D2;olfactory receptor, family 12, subfamily D, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2653,0,0,0,0,18,0,0,123,10,0,0,0,GCSH;glycine cleavage system protein H (aminomethyl carrier),GO:0005960//glycine cleavage complex;GO:0005739//mitochondrion,GO:0032259//methylation;GO:0019464//glycine decarboxylation via glycine cleavage system;GO:0006546//glycine catabolic process,GO:0019899//enzyme binding;GO:0004047//aminomethyltransferase activity,K02437//Ribosome;Biosynthesis of secondary metabolites;Glyoxylate and dicarboxylate metabolism
26532,0,0,0,0,0,0,0,0,5,0,0,0,"OR10H3;olfactory receptor, family 10, subfamily H, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26534,0,0,0,0,0,0,0,0,22,0,0,0,"OR10G2;olfactory receptor, family 10, subfamily G, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
26538,0,0,0,0,0,0,0,0,0,0,3,0,"OR10H2;olfactory receptor, family 10, subfamily H, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26539,0,0,0,0,0,0,0,0,0,84,0,0,"OR10H1;olfactory receptor, family 10, subfamily H, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
26548,0,0,0,0,0,0,0,0,16,0,0,0,ITGB1BP2;integrin beta 1 binding protein (melusin) 2,GO:0030018//Z disc,GO:0007165//signal transduction;GO:0007517//muscle organ development,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0017124//SH3 domain binding;GO:0005178//integrin binding,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction
26574,0,0,0,5,34,0,0,0,17,0,0,0,AATF;apoptosis antagonizing transcription factor,GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005925//focal adhesion;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0040016//embryonic cleavage;GO:0043066//negative regulation of apoptotic process;GO:0042254//ribosome biogenesis;GO:0007155//cell adhesion;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0007346//regulation of mitotic cell cycle;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0032929//negative regulation of superoxide anion generation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0043522//leucine zipper domain binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0048156//tau protein binding,-
26575,0,0,0,0,0,21,0,0,31,0,0,0,RGS17;regulator of G-protein signaling 17,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity,K07524//Axon guidance
26576,0,0,0,0,0,9,0,59,0,0,7,0,SRPK3;SRSF protein kinase 3,-,GO:0007519//skeletal muscle tissue development;GO:0030154//cell differentiation;GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
26577,0,0,0,0,0,0,83,143,15,0,0,0,PCOLCE2;procollagen C-endopeptidase enhancer 2,GO:0070062//extracellular vesicular exosome,GO:0010952//positive regulation of peptidase activity,GO:0016504//peptidase activator activity;GO:0005518//collagen binding;GO:0008201//heparin binding,K14616//Vitamin digestion and absorption
26578,0,29,1,4,31,13,0,0,24,0,10,0,OSTF1;osteoclast stimulating factor 1,GO:0005737//cytoplasm;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome,GO:0001503//ossification;GO:0007165//signal transduction,GO:0017124//SH3 domain binding;GO:0005515//protein binding,K08803//Pathways in cancer;Bladder cancer
26579,0,0,0,0,0,0,0,0,0,0,7,0,MYEOV;myeloma overexpressed,-,-,-,-
2658,0,0,0,0,0,0,0,0,15,0,0,0,GDF2;growth differentiation factor 2,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,"GO:0030509//BMP signaling pathway;GO:0030308//negative regulation of cell growth;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045766//positive regulation of angiogenesis;GO:0001503//ossification;GO:0032924//activin receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0071773//cellular response to BMP stimulus;GO:0051216//cartilage development;GO:0045669//positive regulation of osteoblast differentiation;GO:2000279//negative regulation of DNA biosynthetic process;GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0006879//cellular iron ion homeostasis;GO:0008156//negative regulation of DNA replication;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0045603//positive regulation of endothelial cell differentiation;GO:0010596//negative regulation of endothelial cell migration;GO:0032757//positive regulation of interleukin-8 production;GO:0040007//growth;GO:0001649//osteoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048514//blood vessel morphogenesis;GO:0016525//negative regulation of angiogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001569//patterning of blood vessels",GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity,-
26580,0,17,15,10,0,0,0,0,0,0,0,0,BSCL2;Berardinelli-Seip congenital lipodystrophy 2 (seipin),GO:0030176//integral component of endoplasmic reticulum membrane,GO:0050995//negative regulation of lipid catabolic process;GO:0016042//lipid catabolic process;GO:0019915//lipid storage;GO:0008219//cell death;GO:0034389//lipid particle organization;GO:0045444//fat cell differentiation,-,-
26585,48,7,14,0,0,19,0,0,0,0,15,0,"GREM1;gremlin 1, DAN family BMP antagonist",GO:0005615//extracellular space,GO:0010717//regulation of epithelial to mesenchymal transition;GO:0002092//positive regulation of receptor internalization;GO:0051973//positive regulation of telomerase activity;GO:0033689//negative regulation of osteoblast proliferation;GO:0090291//negative regulation of osteoclast proliferation;GO:0090027//negative regulation of monocyte chemotaxis;GO:0000902//cell morphogenesis;GO:0032872//regulation of stress-activated MAPK cascade;GO:0072331//signal transduction by p53 class mediator;GO:1900155//negative regulation of bone trabecula formation;GO:0030514//negative regulation of BMP signaling pathway;GO:0007165//signal transduction;GO:0048263//determination of dorsal identity;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:1900158//negative regulation of bone mineralization involved in bone maturation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0030199//collagen fibril organization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:2000273//positive regulation of receptor activity;GO:0030502//negative regulation of bone mineralization;GO:0008284//positive regulation of cell proliferation;GO:0046851//negative regulation of bone remodeling;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity,GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0005125//cytokine activity;GO:0016015//morphogen activity;GO:0005515//protein binding;GO:0036122//BMP binding;GO:0048018//receptor agonist activity,K01645//Wnt signaling pathway
26586,0,0,0,3,15,0,30,57,29,45,9,0,CKAP2;cytoskeleton associated protein 2,GO:0005881//cytoplasmic microtubule;GO:0005813//centrosome;GO:0000922//spindle pole,GO:0007026//negative regulation of microtubule depolymerization;GO:0006915//apoptotic process;GO:0000281//mitotic cytokinesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,-,-
26589,0,35,0,3,0,0,0,0,24,0,0,0,MRPL46;mitochondrial ribosomal protein L46,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0008152//metabolic process,GO:0016787//hydrolase activity,"K08860//Protein processing in endoplasmic reticulum;Herpes simplex infection;Hepatitis C;Alzheimer's disease;Measles;Influenza A;Epstein-Barr virus infection;K05607//Metabolic pathways;Valine, leucine and isoleucine degradation"
2660,0,0,0,0,0,6,23,0,23,53,0,0,MSTN;myostatin,GO:0005737//cytoplasm;GO:0005615//extracellular space,"GO:0014732//skeletal muscle atrophy;GO:0014850//response to muscle activity;GO:0071549//cellular response to dexamethasone stimulus;GO:0022602//ovulation cycle process;GO:0043627//response to estrogen;GO:0007517//muscle organ development;GO:0043403//skeletal muscle tissue regeneration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0014741//negative regulation of muscle hypertrophy;GO:0009408//response to heat;GO:0009629//response to gravity;GO:0051602//response to electrical stimulus;GO:0033574//response to testosterone;GO:0048632//negative regulation of skeletal muscle tissue growth;GO:0045471//response to ethanol",GO:0005102//receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0008083//growth factor activity,-
26608,0,0,0,0,0,46,0,0,0,0,0,0,TBL2;transducin (beta)-like 2,-,-,GO:0044822//poly(A) RNA binding,K03130//Herpes simplex infection;Basal transcription factors;K13917//mRNA surveillance pathway
26609,0,0,0,0,0,0,0,0,2,0,0,0,"VCX;variable charge, X-linked",GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0007283//spermatogenesis;GO:0042255//ribosome assembly,GO:0003682//chromatin binding,K10583//Ubiquitin mediated proteolysis
2661,0,1358,324,1728,1507,10,0,258,66,1,656,0,GDF9;growth differentiation factor 9,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0001555//oocyte growth;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2000870//regulation of progesterone secretion;GO:0030308//negative regulation of cell growth;GO:0008284//positive regulation of cell proliferation;GO:0007292//female gamete generation,GO:0005125//cytokine activity;GO:0008083//growth factor activity,-
26610,0,0,1,17,40,22,0,0,31,0,0,0,ELP4;elongator acetyltransferase complex subunit 4,"GO:0005737//cytoplasm;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0008023//transcription elongation factor complex;GO:0033588//Elongator holoenzyme complex",GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0045859//regulation of protein kinase activity;GO:0016573//histone acetylation;GO:0006368//transcription elongation from RNA polymerase II promoter,GO:0008607//phosphorylase kinase regulator activity;GO:0005515//protein binding;GO:0004402//histone acetyltransferase activity,-
2662,0,0,0,0,0,0,36,0,2,0,0,0,GDF10;growth differentiation factor 10,GO:0005615//extracellular space,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0040007//growth;GO:0001501//skeletal system development;GO:0045444//fat cell differentiation,GO:0008083//growth factor activity;GO:0005125//cytokine activity,-
26628,0,0,0,0,0,0,19,0,16,0,0,158,"OR7E47P;olfactory receptor, family 7, subfamily E, member 47 pseudogene",-,-,-,K04257//Olfactory transduction
2664,0,0,1,0,29,0,0,1,37,0,8,0,GDI1;GDP dissociation inhibitor 1,GO:0030496//midbody;GO:0005794//Golgi apparatus;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0090315//negative regulation of protein targeting to membrane;GO:0043547//positive regulation of GTPase activity;GO:0032482//Rab protein signal transduction;GO:0051592//response to calcium ion;GO:0050771//negative regulation of axonogenesis;GO:0015031//protein transport,GO:0017137//Rab GTPase binding;GO:0005093//Rab GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0005092//GDP-dissociation inhibitor activity;GO:0005515//protein binding,-
26648,0,0,0,0,0,0,8,0,0,0,0,0,"OR7E24;olfactory receptor, family 7, subfamily E, member 24",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2665,0,39,0,79,243,0,43,0,5,0,23,0,GDI2;GDP dissociation inhibitor 2,GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane,GO:0007165//signal transduction;GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005097//Rab GTPase activator activity;GO:0005093//Rab GDP-dissociation inhibitor activity,-
26659,0,0,0,0,0,0,64,0,0,0,0,0,"OR7A5;olfactory receptor, family 7, subfamily A, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
266629,47,0,0,0,0,0,59,0,60,0,10,0,SEC14L3;SEC14-like 3 (S. cerevisiae),GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006810//transport,GO:0008289//lipid binding;GO:0005215//transporter activity,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series
266655,0,320,130,421,599,34,52,71,33,0,470,0,LINC00094;long intergenic non-protein coding RNA 94,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
266675,0,0,0,0,0,0,0,1,17,165,1,0,BEST4;bestrophin 4,GO:0034707//chloride channel complex;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity,-
266697,0,0,0,0,0,0,0,0,32,0,0,0,POM121L4P;POM121 transmembrane nucleoporin-like 4 pseudogene,-,-,-,K14316//RNA transport
266722,0,0,0,0,0,6,64,0,42,0,0,0,HS6ST3;heparan sulfate 6-O-sulfotransferase 3,GO:0016021//integral component of membrane,"GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification",-,K08103//Glycosaminoglycan biosynthesis - heparan sulfate
266727,0,0,0,0,0,11,16,0,67,152,13,0,MDGA1;MAM domain containing glycosylphosphatidylinositol anchor 1,GO:0046658//anchored component of plasma membrane;GO:0005615//extracellular space,GO:0021527//spinal cord association neuron differentiation;GO:0021799//cerebral cortex radially oriented cell migration;GO:0007420//brain development;GO:0001764//neuron migration,-,K06255//ECM-receptor interaction
266743,0,0,0,0,0,0,0,0,32,0,7,0,NPAS4;neuronal PAS domain protein 4,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0007165//signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0004871//signal transducer activity;GO:0046982//protein heterodimerization activity,-
266747,0,0,0,0,14,37,27,0,34,0,10,0,RGL4;ral guanine nucleotide dissociation stimulator-like 4,GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity,K08732//Pathways in cancer;Pancreatic cancer;Colorectal cancer
2668,0,0,0,0,0,0,0,0,0,0,10,0,GDNF;glial cell derived neurotrophic factor,GO:0005576//extracellular region,GO:0072107//positive regulation of ureteric bud formation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0060688//regulation of morphogenesis of a branching structure;GO:0007399//nervous system development;GO:0001755//neural crest cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001941//postsynaptic membrane organization;GO:0043524//negative regulation of neuron apoptotic process;GO:0048255//mRNA stabilization;GO:0008344//adult locomotory behavior;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0021784//postganglionic parasympathetic nervous system development;GO:0007165//signal transduction;GO:0032770//positive regulation of monooxygenase activity;GO:0048484//enteric nervous system development;GO:0060676//ureteric bud formation;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0051584//regulation of dopamine uptake involved in synaptic transmission;GO:0007411//axon guidance;GO:0043066//negative regulation of apoptotic process;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0030432//peristalsis;GO:0048485//sympathetic nervous system development;GO:0033603//positive regulation of dopamine secretion;GO:0001656//metanephros development;GO:0031175//neuron projection development;GO:0001759//organ induction,GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding,-
266812,0,0,0,11,1,0,0,0,0,0,0,0,NAP1L5;nucleosome assembly protein 1-like 5,GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
26682,1,0,0,0,0,0,14,0,0,0,0,0,"OR4F4;olfactory receptor, family 4, subfamily F, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26686,0,0,0,0,0,0,0,0,9,0,0,0,"OR4E2;olfactory receptor, family 4, subfamily E, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2669,0,0,0,0,0,0,20,0,16,4,0,0,GEM;GTP binding protein overexpressed in skeletal muscle,GO:0005634//nucleus;GO:0030496//midbody;GO:0072686//mitotic spindle;GO:0051233//spindle midzone;GO:0009898//cytoplasmic side of plasma membrane,GO:0051310//metaphase plate congression;GO:0007264//small GTPase mediated signal transduction;GO:0007067//mitotic nuclear division;GO:0007165//signal transduction;GO:0006955//immune response;GO:0051276//chromosome organization;GO:0006184//GTP catabolic process;GO:0007166//cell surface receptor signaling pathway,GO:0005515//protein binding;GO:0019003//GDP binding;GO:0005516//calmodulin binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
266919,0,0,0,0,0,0,0,0,14,0,0,0,LINC00307;long intergenic non-protein coding RNA 307,-,-,-,-
26693,0,0,0,0,0,0,0,0,6,0,0,0,"OR2V1;olfactory receptor, family 2, subfamily V, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26696,0,0,0,0,0,0,0,75,12,0,0,0,"OR2T1;olfactory receptor, family 2, subfamily T, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
266971,0,0,0,0,0,0,0,41,7,0,0,8,"PIPSL;PIP5K1A and PSMD4-like, pseudogene",GO:0005737//cytoplasm,GO:0046854//phosphatidylinositol phosphorylation,GO:0016307//phosphatidylinositol phosphate kinase activity,K00889//Phosphatidylinositol signaling system;Regulation of actin cytoskeleton;Metabolic pathways;Endocytosis;Fc gamma R-mediated phagocytosis;Inositol phosphate metabolism;Focal adhesion
266977,54,0,0,0,0,19,35,25,64,0,2,0,GPR110;G protein-coupled receptor 110,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
267,0,2,29,0,1,27,0,63,14,0,0,0,"AMFR;autocrine motility factor receptor, E3 ubiquitin protein ligase",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0000836//Hrd1p ubiquitin ligase complex;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043234//protein complex;GO:0030425//dendrite;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007568//aging;GO:0051259//protein oligomerization;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007611//learning or memory;GO:0007165//signal transduction;GO:0000209//protein polyubiquitination;GO:0006928//cellular component movement,GO:0004872//receptor activity;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K10636//Protein processing in endoplasmic reticulum
2670,0,0,0,0,0,14,0,0,31,0,0,0,GFAP;glial fibrillary acidic protein,GO:0005882//intermediate filament;GO:0005829//cytosol;GO:0097449//astrocyte projection;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0044297//cell body,GO:0030198//extracellular matrix organization;GO:0060020//Bergmann glial cell differentiation;GO:0014002//astrocyte development;GO:0009611//response to wounding;GO:0010977//negative regulation of neuron projection development;GO:0031102//neuron projection regeneration;GO:0010625//positive regulation of Schwann cell proliferation;GO:0060291//long-term synaptic potentiation;GO:0051580//regulation of neurotransmitter uptake;GO:0045109//intermediate filament organization,GO:0005178//integrin binding;GO:0019900//kinase binding;GO:0005200//structural constituent of cytoskeleton,-
267002,0,0,0,0,1,25,0,67,54,0,0,0,PGBD2;piggyBac transposable element derived 2,-,-,-,-
267012,0,0,0,0,0,0,0,8,1,0,0,0,DAOA;D-amino acid oxidase activator,GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm,GO:1900758//negative regulation of D-amino-acid oxidase activity;GO:0043085//positive regulation of catalytic activity,GO:0019899//enzyme binding;GO:0008047//enzyme activator activity,-
267020,0,0,0,0,0,0,0,0,13,0,0,0,"ATP5L2;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",GO:0015986//ATP synthesis coupled proton transport,GO:0015078//hydrogen ion transmembrane transporter activity,K02140//Oxidative phosphorylation;Metabolic pathways
26707,0,0,0,0,0,29,0,0,0,0,0,0,"OR2J2;olfactory receptor, family 2, subfamily J, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2671,0,0,0,3,0,0,31,0,8,0,18,0,"GFER;growth factor, augmenter of liver regeneration",GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005576//extracellular region;GO:0005758//mitochondrial intermembrane space,GO:0055114//oxidation-reduction process;GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process,GO:0050660//flavin adenine dinucleotide binding;GO:0008083//growth factor activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0016972//thiol oxidase activity;GO:0005515//protein binding,-
26716,0,0,0,0,0,0,0,0,0,0,1,0,"OR2H1;olfactory receptor, family 2, subfamily H, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2672,1,0,0,0,4,8,0,0,16,0,8,0,GFI1;growth factor independent 1 transcription repressor,GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0016604//nuclear body,"GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0016032//viral process;GO:0042491//auditory receptor cell differentiation;GO:0042660//positive regulation of cell fate specification;GO:0071222//cellular response to lipopolysaccharide;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006351//transcription, DNA-templated;GO:0009996//negative regulation of cell fate specification;GO:0007638//mechanosensory behavior;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070105//positive regulation of interleukin-6-mediated signaling pathway;GO:0045165//cell fate commitment;GO:0042472//inner ear morphogenesis;GO:0010977//negative regulation of neuron projection development",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
2673,0,241,4,276,949,53,53,0,72,0,5,0,GFPT1;glutamine--fructose-6-phosphate transaminase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044267//cellular protein metabolic process;GO:0006112//energy reserve metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006042//glucosamine biosynthetic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0006541//glutamine metabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0032922//circadian regulation of gene expression;GO:0016051//carbohydrate biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0018279//protein N-linked glycosylation via asparagine;GO:0009744//response to sucrose;GO:0051289//protein homotetramerization,GO:0016597//amino acid binding;GO:0030246//carbohydrate binding;GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity,"K00820//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
26735,0,0,0,0,0,0,18,0,0,0,0,0,"OR1L3;olfactory receptor, family 1, subfamily L, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2674,4,0,0,0,0,25,14,0,5,0,0,0,GFRA1;GDNF family receptor alpha 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane,GO:0007411//axon guidance;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway,GO:0005102//receptor binding;GO:0016167//glial cell-derived neurotrophic factor receptor activity,-
26740,0,0,0,0,0,0,0,0,19,0,0,0,"OR1J2;olfactory receptor, family 1, subfamily J, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
26747,87,0,0,0,12,0,0,0,50,0,0,0,NUFIP1;nuclear fragile X mental retardation protein interacting protein 1,GO:0005730//nucleolus;GO:0005726//perichromatin fibrils;GO:0005634//nucleus;GO:0048786//presynaptic active zone;GO:0016363//nuclear matrix;GO:0008023//transcription elongation factor complex;GO:0070761//pre-snoRNP complex;GO:0022626//cytosolic ribosome,GO:0000492//box C/D snoRNP assembly;GO:0006396//RNA processing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,"GO:0003677//DNA binding;GO:0030515//snoRNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0003723//RNA binding",-
26749,91,0,0,0,0,0,0,1,0,0,0,0,GAGE2E;G antigen 2E,-,-,-,-
2675,0,0,0,0,0,23,12,0,13,0,14,0,GFRA2;GDNF family receptor alpha 2,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane;GO:0019898//extrinsic component of membrane,GO:0007399//nervous system development;GO:0031953//negative regulation of protein autophosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway,GO:0016167//glial cell-derived neurotrophic factor receptor activity,-
26750,82,49,0,41,95,54,0,0,47,0,0,0,"RPS6KC1;ribosomal protein S6 kinase, 52kDa, polypeptide 1",GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005769//early endosome;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0004674//protein serine/threonine kinase activity,K04373//MAPK signaling pathway;mTOR signaling pathway;Neurotrophin signaling pathway;Oocyte meiosis;Progesterone-mediated oocyte maturation;Long-term potentiation
26751,0,0,0,6,13,0,0,0,0,0,0,11,SH3YL1;SH3 and SYLF domain containing 1,GO:0032587//ruffle membrane,GO:1900027//regulation of ruffle assembly;GO:0006661//phosphatidylinositol biosynthetic process,GO:0035091//phosphatidylinositol binding;GO:0019902//phosphatase binding,K08010//Phagosome;Osteoclast differentiation;Leishmaniasis;Leukocyte transendothelial migration;K07366//T cell receptor signaling pathway;K11247//Endocytosis;K04364//Chronic myeloid leukemia;T cell receptor signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Renal cell carcinoma;ErbB signaling pathway;Insulin signaling pathway;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Alcoholism;Prostate cancer;Hepatitis C;Neurotrophin signaling pathway;MAPK signaling pathway - fly;Osteoclast differentiation;Non-small cell lung cancer;Endometrial cancer;Dorso-ventral axis formation;Focal adhesion;Glioma;Acute myeloid leukemia;Jak-STAT signaling pathway;Fc epsilon RI signaling pathway;B cell receptor signaling pathway
2676,0,0,0,0,0,71,19,0,0,0,7,0,GFRA3;GDNF family receptor alpha 3,GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane,GO:0001764//neuron migration;GO:0048485//sympathetic nervous system development;GO:0007422//peripheral nervous system development;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0007399//nervous system development,GO:0005102//receptor binding;GO:0008046//axon guidance receptor activity,-
26762,0,0,0,0,0,0,81,0,0,0,0,0,HAVCR1;hepatitis A virus cellular receptor 1,GO:0016021//integral component of membrane,GO:0016032//viral process;GO:0009615//response to virus,GO:0001618//virus receptor activity,K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
26768,7,0,0,0,0,0,0,0,0,0,0,0,"RNU105A;RNA, U105A small nucleolar",-,-,-,-
2677,2,437,373,760,1015,30,41,59,60,0,761,0,GGCX;gamma-glutamyl carboxylase,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0043687//post-translational protein modification;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0006464//cellular protein modification process;GO:0007596//blood coagulation;GO:0044267//cellular protein metabolic process,GO:0008488//gamma-glutamyl carboxylase activity,K10106//Ubiquinone and other terpenoid-quinone biosynthesis
26773,0,0,0,0,0,0,4,0,0,0,0,0,"SNORD4A;small nucleolar RNA, C/D box 4A",-,-,-,-
2678,0,0,0,7,0,0,4,18,41,8,2,0,GGT1;gamma-glutamyltransferase 1,GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031362//anchored component of external side of plasma membrane,GO:0007283//spermatogenesis;GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process;GO:0006749//glutathione metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0006750//glutathione biosynthetic process;GO:0006691//leukotriene metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0019370//leukotriene biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019344//cysteine biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0002682//regulation of immune system process;GO:0006536//glutamate metabolic process;GO:0050727//regulation of inflammatory response;GO:0006751//glutathione catabolic process;GO:0031638//zymogen activation,GO:0005515//protein binding;GO:0003840//gamma-glutamyltransferase activity;GO:0036374//glutathione hydrolase activity,K00681//Glutathione metabolism;Taurine and hypotaurine metabolism;Cyanoamino acid metabolism;Arachidonic acid metabolism;Metabolic pathways
2679,1,0,0,0,0,0,26,0,25,1,3,0,GGT3P;gamma-glutamyltransferase 3 pseudogene,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0031362//anchored component of external side of plasma membrane,GO:0006749//glutathione metabolic process;GO:0006508//proteolysis;GO:0019370//leukotriene biosynthetic process;GO:0006750//glutathione biosynthetic process,GO:0036374//glutathione hydrolase activity;GO:0003840//gamma-glutamyltransferase activity,K00681//Arachidonic acid metabolism;Metabolic pathways;Glutathione metabolism;Taurine and hypotaurine metabolism;Cyanoamino acid metabolism
26795,0,0,0,0,0,0,0,0,0,3,0,0,"SNORD54;small nucleolar RNA, C/D box 54",-,-,-,-
268,0,0,0,0,0,1,0,0,32,0,0,0,AMH;anti-Mullerian hormone,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0010628//positive regulation of gene expression;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007548//sex differentiation;GO:0007530//sex determination;GO:0001655//urogenital system development;GO:0001880//Mullerian duct regression;GO:0001546//preantral ovarian follicle growth;GO:0007267//cell-cell signaling;GO:0007568//aging;GO:0042493//response to drug;GO:0014070//response to organic cyclic compound;GO:0007506//gonadal mesoderm development,GO:0005160//transforming growth factor beta receptor binding;GO:0005102//receptor binding;GO:0008083//growth factor activity;GO:0005179//hormone activity,K04665//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
26820,0,0,0,0,0,0,0,0,14,0,0,0,"SNORD24;small nucleolar RNA, C/D box 24",-,-,-,-
26828,0,0,0,0,0,0,0,0,0,0,6,0,"RNU5F-1;RNA, U5F small nuclear 1",-,-,-,-
2683,0,13,0,14,28,1,21,0,23,117,0,0,"B4GALT1;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0031526//brush border membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000138//Golgi trans cisterna;GO:0030112//glycocalyx;GO:0030057//desmosome;GO:0032580//Golgi cisterna membrane;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane,GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0032504//multicellular organism reproduction;GO:0051270//regulation of cellular component movement;GO:0048754//branching morphogenesis of an epithelial tube;GO:0006487//protein N-linked glycosylation;GO:0008285//negative regulation of cell proliferation;GO:0060055//angiogenesis involved in wound healing;GO:0045136//development of secondary sexual characteristics;GO:0007339//binding of sperm to zona pellucida;GO:0009312//oligosaccharide biosynthetic process;GO:0030198//extracellular matrix organization;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044281//small molecule metabolic process;GO:0005989//lactose biosynthetic process;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0060046//regulation of acrosome reaction;GO:0007155//cell adhesion;GO:0044267//cellular protein metabolic process;GO:0030879//mammary gland development;GO:0006012//galactose metabolic process;GO:0002064//epithelial cell development;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0002526//acute inflammatory response;GO:0043687//post-translational protein modification;GO:0007219//Notch signaling pathway;GO:0007341//penetration of zona pellucida;GO:0007338//single fertilization;GO:0050900//leukocyte migration;GO:0030203//glycosaminoglycan metabolic process,"GO:0030145//manganese ion binding;GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0004461//lactose synthase activity;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0042803//protein homodimerization activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0008378//galactosyltransferase activity;GO:0008092//cytoskeletal protein binding",K07966//N-Glycan biosynthesis;Metabolic pathways;Galactose metabolism;Glycosphingolipid biosynthesis - lacto and neolacto series;Glycosaminoglycan biosynthesis - keratan sulfate;Other types of O-glycan biosynthesis
2686,54,0,0,0,0,0,0,180,31,0,0,0,GGT7;gamma-glutamyltransferase 7,GO:0031362//anchored component of external side of plasma membrane;GO:0016021//integral component of membrane,GO:0006750//glutathione biosynthetic process;GO:0006508//proteolysis;GO:0019370//leukotriene biosynthetic process;GO:0006749//glutathione metabolic process,GO:0036374//glutathione hydrolase activity;GO:0003840//gamma-glutamyltransferase activity,K00681//Arachidonic acid metabolism;Metabolic pathways;Taurine and hypotaurine metabolism;Glutathione metabolism;Cyanoamino acid metabolism
26860,0,0,0,0,6,0,0,0,0,0,0,0,"RNU1-13P;RNA, U1 small nuclear 13, pseudogene",-,-,-,-
26872,0,0,0,0,13,0,1,0,12,0,3,0,STEAP1;six transmembrane epithelial antigen of the prostate 1,GO:0010008//endosome membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,GO:0055085//transmembrane transport;GO:0055072//iron ion homeostasis;GO:0055114//oxidation-reduction process;GO:0006811//ion transport,GO:0046872//metal ion binding;GO:0015267//channel activity;GO:0016491//oxidoreductase activity;GO:0005215//transporter activity,K14737//Mineral absorption
26873,0,0,0,0,1,38,0,0,26,0,6,0,OPLAH;5-oxoprolinase (ATP-hydrolysing),GO:0005829//cytosol,GO:1901687//glutathione derivative biosynthetic process;GO:0006750//glutathione biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0017168//5-oxoprolinase (ATP-hydrolyzing) activity,K01469//Glutathione metabolism
2688,0,0,0,0,0,0,0,0,12,0,0,0,GH1;growth hormone 1,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0043406//positive regulation of MAP kinase activity;GO:0070977//bone maturation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060396//growth hormone receptor signaling pathway;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0010535//positive regulation of activation of JAK2 kinase activity;GO:0046427//positive regulation of JAK-STAT cascade;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0015758//glucose transport;GO:0032355//response to estradiol;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0007259//JAK-STAT cascade;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0040018//positive regulation of multicellular organism growth;GO:0002092//positive regulation of receptor internalization;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling,GO:0005179//hormone activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0005148//prolactin receptor binding;GO:0005131//growth hormone receptor binding,K05438//Neuroactive ligand-receptor interaction;Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
2689,0,0,0,0,0,19,0,16,9,162,0,0,GH2;growth hormone 2,GO:0005576//extracellular region,GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway,GO:0005179//hormone activity,K05438//Neuroactive ligand-receptor interaction;Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
269,0,0,0,0,0,1,21,0,11,145,0,0,"AMHR2;anti-Mullerian hormone receptor, type II",GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0023014//signal transduction by phosphorylation;GO:0007548//sex differentiation;GO:0001880//Mullerian duct regression,"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005026//transforming growth factor beta receptor activity, type II;GO:0004872//receptor activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0042562//hormone binding",K04672//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
2690,0,0,1,18,65,6,87,51,42,0,0,0,GHR;growth hormone receptor,GO:0043235//receptor complex;GO:0070195//growth hormone receptor complex;GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0006631//fatty acid metabolic process;GO:0046449//creatinine metabolic process;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0006600//creatine metabolic process;GO:0006101//citrate metabolic process;GO:0000187//activation of MAPK activity;GO:0006549//isoleucine metabolic process;GO:0060396//growth hormone receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0046898//response to cycloheximide;GO:0019221//cytokine-mediated signaling pathway;GO:0006897//endocytosis;GO:0007259//JAK-STAT cascade;GO:0006573//valine metabolic process;GO:0031623//receptor internalization;GO:0032355//response to estradiol;GO:0019530//taurine metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0044236//multicellular organismal metabolic process;GO:0042977//activation of JAK2 kinase activity;GO:0040018//positive regulation of multicellular organism growth;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0006103//2-oxoglutarate metabolic process;GO:0000255//allantoin metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0040014//regulation of multicellular organism growth;GO:0006105//succinate metabolic process,GO:0005515//protein binding;GO:0070064//proline-rich region binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0019838//growth factor binding;GO:0004896//cytokine receptor activity;GO:0017046//peptide hormone binding,K05080//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;Neuroactive ligand-receptor interaction
2691,0,0,0,0,0,0,0,0,9,0,0,0,GHRH;growth hormone releasing hormone,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0043195//terminal bouton,"GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep;GO:0032094//response to food;GO:0021984//adenohypophysis development;GO:0019933//cAMP-mediated signaling;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0040018//positive regulation of multicellular organism growth;GO:0007267//cell-cell signaling;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0060124//positive regulation of growth hormone secretion;GO:0030252//growth hormone secretion",GO:0031770//growth hormone-releasing hormone receptor binding;GO:0016608//growth hormone-releasing hormone activity,-
2692,161,0,0,0,3,22,0,0,35,142,21,0,GHRHR;growth hormone releasing hormone receptor,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0030141//secretory granule;GO:0005637//nuclear inner membrane;GO:0016363//nuclear matrix;GO:0005640//nuclear outer membrane,GO:0030819//positive regulation of cAMP biosynthetic process;GO:0019933//cAMP-mediated signaling;GO:0032869//cellular response to insulin stimulus;GO:0007190//activation of adenylate cyclase activity;GO:0060133//somatotropin secreting cell development;GO:0060124//positive regulation of growth hormone secretion;GO:0051384//response to glucocorticoid;GO:0032868//response to insulin;GO:0008284//positive regulation of cell proliferation;GO:0048469//cell maturation;GO:0048609//multicellular organismal reproductive process;GO:0008340//determination of adult lifespan;GO:0030104//water homeostasis;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0043627//response to estrogen;GO:0033143//regulation of intracellular steroid hormone receptor signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0051246//regulation of protein metabolic process;GO:0030252//growth hormone secretion;GO:0040018//positive regulation of multicellular organism growth;GO:0007595//lactation;GO:0042445//hormone metabolic process,GO:0017046//peptide hormone binding;GO:0019838//growth factor binding;GO:0004930//G-protein coupled receptor activity;GO:0016520//growth hormone-releasing hormone receptor activity;GO:0005515//protein binding,K04584//Neuroactive ligand-receptor interaction
2693,17,0,0,0,0,19,0,0,0,0,8,0,GHSR;growth hormone secretagogue receptor,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0045121//membrane raft,GO:0008154//actin polymerization or depolymerization;GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0045923//positive regulation of fatty acid metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0008343//adult feeding behavior;GO:0042536//negative regulation of tumor necrosis factor biosynthetic process;GO:0032691//negative regulation of interleukin-1 beta production;GO:0032094//response to food;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0032100//positive regulation of appetite;GO:0030252//growth hormone secretion;GO:0009725//response to hormone;GO:0040018//positive regulation of multicellular organism growth;GO:0043134//regulation of hindgut contraction;GO:0050728//negative regulation of inflammatory response;GO:0046676//negative regulation of insulin secretion;GO:0051963//regulation of synapse assembly;GO:0046697//decidualization,GO:0001616//growth hormone secretagogue receptor activity;GO:0016520//growth hormone-releasing hormone receptor activity;GO:0017046//peptide hormone binding;GO:0004930//G-protein coupled receptor activity,K04284//Neuroactive ligand-receptor interaction
2694,0,0,0,0,0,0,0,1,13,0,7,0,GIF;gastric intrinsic factor (vitamin B synthesis),GO:0043202//lysosomal lumen;GO:0005902//microvillus;GO:0016324//apical plasma membrane;GO:0005615//extracellular space;GO:0005768//endosome;GO:0005576//extracellular region,GO:0006824//cobalt ion transport;GO:0006766//vitamin metabolic process;GO:0009235//cobalamin metabolic process;GO:0015889//cobalamin transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0031419//cobalamin binding,K14615//Vitamin digestion and absorption
2695,0,0,0,0,0,12,0,0,0,0,0,0,GIP;gastric inhibitory polypeptide,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0034774//secretory granule lumen;GO:0005788//endoplasmic reticulum lumen;GO:0043025//neuronal cell body,GO:0014070//response to organic cyclic compound;GO:0008344//adult locomotory behavior;GO:0031018//endocrine pancreas development;GO:0019233//sensory perception of pain;GO:0032024//positive regulation of insulin secretion;GO:0070094//positive regulation of glucagon secretion;GO:0070328//triglyceride homeostasis;GO:0007165//signal transduction;GO:0007613//memory;GO:0060291//long-term synaptic potentiation;GO:0043200//response to amino acid;GO:0048678//response to axon injury;GO:0044267//cellular protein metabolic process;GO:0043434//response to peptide hormone;GO:0010828//positive regulation of glucose transport;GO:0035640//exploration behavior;GO:0042493//response to drug;GO:0007565//female pregnancy;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0009749//response to glucose;GO:0055123//digestive system development;GO:0042594//response to starvation;GO:0033993//response to lipid;GO:0050796//regulation of insulin secretion;GO:0010269//response to selenium ion,GO:0005179//hormone activity,-
26952,0,0,0,0,0,0,0,0,42,0,0,0,SMR3A;submaxillary gland androgen regulated protein 3A,GO:0005576//extracellular region,-,-,-
26953,0,0,1,1,16,0,0,0,28,0,0,0,RANBP6;RAN binding protein 6,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0015031//protein transport,GO:0005515//protein binding,K14293//RNA transport
26958,0,0,0,8,48,0,0,0,34,0,0,0,"COPG2;coatomer protein complex, subunit gamma 2",GO:0030126//COPI vesicle coat;GO:0005829//cytosol,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport",GO:0005198//structural molecule activity,-
26959,0,276,264,337,385,0,37,76,47,0,312,1,HBP1;HMG-box transcription factor 1,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0016055//Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0043268//positive regulation of potassium ion transport;GO:0007050//cell cycle arrest;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003723//RNA binding,-
2696,0,0,0,0,0,0,1,0,28,0,14,0,GIPR;gastric inhibitory polypeptide receptor,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0031018//endocrine pancreas development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose;GO:0048678//response to axon injury;GO:0070542//response to fatty acid;GO:0051592//response to calcium ion;GO:0007584//response to nutrient;GO:0038192//gastric inhibitory peptide signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0006091//generation of precursor metabolites and energy;GO:0007166//cell surface receptor signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0016519//gastric inhibitory peptide receptor activity;GO:0017046//peptide hormone binding,K04580//Neuroactive ligand-receptor interaction
26960,0,117,0,17,94,0,39,61,81,289,7,0,NBEA;neurobeachin,GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005802//trans-Golgi network,GO:0008104//protein localization,GO:0019901//protein kinase binding,K14753//Measles;K10260//Ubiquitin mediated proteolysis
2697,0,0,0,0,0,0,1,0,22,0,0,0,"GJA1;gap junction protein, alpha 1, 43kDa",GO:0016324//apical plasma membrane;GO:0005921//gap junction;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0045121//membrane raft;GO:0043292//contractile fiber;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0005922//connexon complex;GO:0016328//lateral plasma membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0014704//intercalated disc;GO:0000139//Golgi membrane;GO:0005916//fascia adherens;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome;GO:0005771//multivesicular body;GO:0005925//focal adhesion,GO:0048812//neuron projection morphogenesis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030500//regulation of bone mineralization;GO:0045732//positive regulation of protein catabolic process;GO:0001701//in utero embryonic development;GO:0003104//positive regulation of glomerular filtration;GO:0007267//cell-cell signaling;GO:0055085//transmembrane transport;GO:0046850//regulation of bone remodeling;GO:0002070//epithelial cell maturation;GO:0001947//heart looping;GO:0034405//response to fluid shear stress;GO:0042733//embryonic digit morphogenesis;GO:0007512//adult heart development;GO:0045909//positive regulation of vasodilation;GO:0007165//signal transduction;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0048514//blood vessel morphogenesis;GO:0016264//gap junction assembly;GO:0043434//response to peptide hormone;GO:0071260//cellular response to mechanical stimulus;GO:0061024//membrane organization;GO:0003294//atrial ventricular junction remodeling;GO:0015867//ATP transport;GO:0034220//ion transmembrane transport;GO:0045844//positive regulation of striated muscle tissue development;GO:0006915//apoptotic process;GO:0007507//heart development;GO:0002088//lens development in camera-type eye;GO:0003158//endothelium development;GO:0051259//protein oligomerization;GO:0009268//response to pH;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0043403//skeletal muscle tissue regeneration;GO:0010629//negative regulation of gene expression;GO:2000810//regulation of tight junction assembly;GO:0086014//atrial cardiac muscle cell action potential;GO:0002544//chronic inflammatory response;GO:0010628//positive regulation of gene expression;GO:0010652//positive regulation of cell communication by chemical coupling;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0001649//osteoblast differentiation;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0010232//vascular transport;GO:0045907//positive regulation of vasoconstriction;GO:0006936//muscle contraction;GO:2000987//positive regulation of behavioral fear response;GO:0010644//cell communication by electrical coupling;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0051924//regulation of calcium ion transport;GO:0001764//neuron migration;GO:0006810//transport,GO:0071253//connexin binding;GO:0017124//SH3 domain binding;GO:0004871//signal transducer activity;GO:0005243//gap junction channel activity;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0097110//scaffold protein binding;GO:0005102//receptor binding;GO:0015075//ion transmembrane transporter activity;GO:0030165//PDZ domain binding,K07372//Gap junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
26973,0,52,0,1,68,0,0,0,47,103,7,0,CHORDC1;cysteine and histidine-rich domain (CHORD) containing 1,-,GO:0010824//regulation of centrosome duplication;GO:0006950//response to stress;GO:0061077//chaperone-mediated protein folding;GO:1900034//regulation of cellular response to heat;GO:2000299//negative regulation of Rho-dependent protein serine/threonine kinase activity,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0051879//Hsp90 protein binding,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction
26974,0,0,0,0,12,18,15,0,16,0,0,0,ZNF285;zinc finger protein 285,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
26984,43,1,0,0,0,13,0,0,0,0,0,0,SEC22A;SEC22 vesicle trafficking protein homolog A (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0006888//ER to Golgi vesicle-mediated transport,GO:0005215//transporter activity,-
26985,70,42,0,19,146,21,0,1,43,0,5,0,"AP3M1;adaptor-related protein complex 3, mu 1 subunit",GO:0030659//cytoplasmic vesicle membrane;GO:0005794//Golgi apparatus;GO:0030131//clathrin adaptor complex;GO:0005764//lysosome;GO:0005765//lysosomal membrane,GO:0048490//anterograde synaptic vesicle transport;GO:0006622//protein targeting to lysosome;GO:0008089//anterograde axon cargo transport,GO:0017137//Rab GTPase binding;GO:0005515//protein binding,K12398//Lysosome
26986,0,268,2,268,1441,0,0,1,54,1,22,46,"PABPC1;poly(A) binding protein, cytoplasmic 1",GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0048255//mRNA stabilization;GO:0045727//positive regulation of translation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006413//translational initiation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0000398//mRNA splicing, via spliceosome;GO:0044267//cellular protein metabolic process;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006378//mRNA polyadenylation;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0008494//translation activator activity;GO:0008266//poly(U) RNA binding;GO:0008022//protein C-terminus binding;GO:0008143//poly(A) binding,K13126//RNA degradation;mRNA surveillance pathway;RNA transport
26993,0,17,0,2,18,0,36,18,26,1,12,0,AKAP8L;A kinase (PRKA) anchor protein 8-like,GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0017151//DEAD/H-box RNA helicase binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K15978//Epstein-Barr virus infection
26994,0,154,0,107,288,0,11,0,2,0,0,0,RNF11;ring finger protein 11,GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0055037//recycling endosome;GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
26995,0,0,0,7,19,0,0,0,17,0,0,0,TRUB2;TruB pseudouridine (psi) synthase family member 2,-,GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing,GO:0009982//pseudouridine synthase activity;GO:0044822//poly(A) RNA binding,-
26996,0,0,0,49,110,6,22,0,0,0,0,0,GPR160;G protein-coupled receptor 160,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
26998,21,0,0,0,0,30,0,0,27,0,0,0,FETUB;fetuin B,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0007339//binding of sperm to zona pellucida;GO:0007338//single fertilization,GO:0008191//metalloendopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity,K03898//Complement and coagulation cascades
26999,0,0,0,11,18,16,49,0,82,178,0,0,CYFIP2;cytoplasmic FMR1 interacting protein 2,GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0070062//extracellular vesicular exosome;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0016337//single organismal cell-cell adhesion;GO:0045862//positive regulation of proteolysis;GO:0045087//innate immune response;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0006915//apoptotic process,GO:0005515//protein binding,K05749//RNA transport;Regulation of actin cytoskeleton
27,0,23,0,23,61,27,8,0,53,0,0,0,"ABL2;ABL proto-oncogene 2, non-receptor tyrosine kinase",GO:0015629//actin cytoskeleton;GO:0005829//cytosol,GO:2000249//regulation of actin cytoskeleton reorganization;GO:0010506//regulation of autophagy;GO:0006464//cellular protein modification process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0051353//positive regulation of oxidoreductase activity;GO:0030100//regulation of endocytosis;GO:2000145//regulation of cell motility;GO:0051017//actin filament bundle assembly;GO:0010976//positive regulation of neuron projection development;GO:0010863//positive regulation of phospholipase C activity;GO:0007165//signal transduction;GO:0007155//cell adhesion;GO:0030155//regulation of cell adhesion;GO:0071300//cellular response to retinoic acid,GO:0051015//actin filament binding;GO:0030145//manganese ion binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0003785//actin monomer binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0000287//magnesium ion binding,K08887//ErbB signaling pathway;Viral myocarditis
270,0,0,0,0,0,19,1,12,0,0,0,0,AMPD1;adenosine monophosphate deaminase 1,GO:0005829//cytosol,GO:0010033//response to organic substance;GO:0043101//purine-containing compound salvage;GO:0032264//IMP salvage;GO:0044281//small molecule metabolic process;GO:0006144//purine nucleobase metabolic process,GO:0046872//metal ion binding;GO:0003876//AMP deaminase activity;GO:0032036//myosin heavy chain binding,K01490//Metabolic pathways;Biosynthesis of secondary metabolites;Purine metabolism
2700,0,0,0,0,0,1,15,45,26,0,22,0,"GJA3;gap junction protein, alpha 3, 46kDa",GO:0005922//connexon complex;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0007601//visual perception;GO:0006810//transport;GO:0007267//cell-cell signaling,GO:0005243//gap junction channel activity,-
27000,0,20,33,29,48,12,0,0,34,0,14,0,"DNAJC2;DnaJ (Hsp40) homolog, subfamily C, member 2",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005829//cytosol,"GO:0006260//DNA replication;GO:2000279//negative regulation of DNA biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0016568//chromatin modification;GO:0051083//'de novo' cotranslational protein folding;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0043130//ubiquitin binding;GO:0003677//DNA binding;GO:0042393//histone binding;GO:0030544//Hsp70 protein binding;GO:0044822//poly(A) RNA binding,-
27005,0,25,0,7,0,23,0,0,19,0,2,0,USP21;ubiquitin specific peptidase 21,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016578//histone deubiquitination",GO:0046872//metal ion binding;GO:0019784//NEDD8-specific protease activity;GO:0008234//cysteine-type peptidase activity;GO:0004843//ubiquitin-specific protease activity;GO:0003713//transcription coactivator activity;GO:0004221//ubiquitin thiolesterase activity,-
2701,0,0,0,0,0,0,0,36,4,0,0,0,"GJA4;gap junction protein, alpha 4, 37kDa",GO:0005922//connexon complex;GO:0005921//gap junction;GO:0005887//integral component of plasma membrane,GO:0007267//cell-cell signaling;GO:0006810//transport;GO:0006816//calcium ion transport;GO:0048265//response to pain;GO:0003158//endothelium development;GO:0007043//cell-cell junction assembly;GO:0001568//blood vessel development,GO:0005515//protein binding,-
27010,0,0,0,0,24,5,0,41,11,0,0,0,TPK1;thiamin pyrophosphokinase 1,GO:0005829//cytosol,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0009229//thiamine diphosphate biosynthetic process;GO:0006766//vitamin metabolic process;GO:0042723//thiamine-containing compound metabolic process;GO:0016310//phosphorylation;GO:0006772//thiamine metabolic process,GO:0016301//kinase activity;GO:0004788//thiamine diphosphokinase activity;GO:0005524//ATP binding,K00949//Thiamine metabolism;Metabolic pathways
27012,0,0,0,0,0,0,22,0,0,0,0,0,"KCNV1;potassium channel, subfamily V, member 1",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization,GO:0015459//potassium channel regulator activity;GO:0008200//ion channel inhibitor activity;GO:0005251//delayed rectifier potassium channel activity,-
27013,0,0,0,0,39,0,0,0,22,0,27,0,CNPPD1;cyclin Pas1/PHO80 domain containing 1,GO:0016021//integral component of membrane,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding,-
27018,0,38,0,58,126,0,13,0,14,0,0,0,NGFRAP1;nerve growth factor receptor (TNFRSF16) associated protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007275//multicellular organismal development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0097190//apoptotic signaling pathway,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005123//death receptor binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process,K12465//Neurotrophin signaling pathway
27019,0,0,51,0,0,16,0,0,18,0,0,0,"DNAI1;dynein, axonemal, intermediate chain 1",GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0030286//dynein complex;GO:0005856//cytoskeleton;GO:0005929//cilium,GO:0003351//epithelial cilium movement;GO:0008152//metabolic process;GO:0030030//cell projection organization,GO:0003774//motor activity;GO:0005515//protein binding,K10409//Huntington's disease
2702,24,48,0,0,0,13,0,46,29,1,0,0,"GJA5;gap junction protein, alpha 5, 40kDa",GO:0014704//intercalated disc;GO:0005922//connexon complex;GO:0005921//gap junction;GO:0005887//integral component of plasma membrane,GO:0086053//AV node cell to bundle of His cell communication by electrical coupling;GO:0003151//outflow tract morphogenesis;GO:0003174//mitral valve development;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0016264//gap junction assembly;GO:0003281//ventricular septum development;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0055117//regulation of cardiac muscle contraction;GO:0001525//angiogenesis;GO:0048844//artery morphogenesis;GO:0003193//pulmonary valve formation;GO:0003283//atrial septum development;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055085//transmembrane transport;GO:0086014//atrial cardiac muscle cell action potential,GO:0055077//gap junction hemi-channel activity;GO:0086077//gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling,-
27020,0,0,0,0,0,0,8,0,40,0,0,1,NPTN;neuroplastin,GO:0042734//presynaptic membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0060291//long-term synaptic potentiation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0050839//cell adhesion molecule binding,-
27022,0,0,0,0,0,0,0,84,0,0,0,0,FOXD3;forkhead box D3,GO:0000790//nuclear chromatin,"GO:0001701//in utero embryonic development;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001829//trophectodermal cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001892//embryonic placenta development",GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
27023,0,0,0,0,0,0,0,0,8,0,0,0,FOXB1;forkhead box B1,GO:0005634//nucleus,"GO:0061379//inferior colliculus development;GO:0022029//telencephalon cell migration;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0001756//somitogenesis;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0021510//spinal cord development;GO:0061374//mammillothalamic axonal tract development;GO:0021794//thalamus development;GO:0007412//axon target recognition;GO:0021855//hypothalamus cell migration;GO:0061381//cell migration in diencephalon;GO:0001655//urogenital system development;GO:0008542//visual learning;GO:0030901//midbrain development;GO:0007595//lactation;GO:0033504//floor plate development;GO:0043524//negative regulation of neuron apoptotic process",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
2703,0,44,0,0,0,0,16,0,0,0,9,0,"GJA8;gap junction protein, alpha 8, 50kDa",GO:0005922//connexon complex;GO:0005887//integral component of plasma membrane,GO:0006810//transport;GO:0007267//cell-cell signaling;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0002088//lens development in camera-type eye;GO:0007601//visual perception,GO:0015267//channel activity,-
27030,0,0,0,25,24,0,45,0,32,73,24,1,MLH3;mutL homolog 3,GO:0005634//nucleus;GO:0000795//synaptonemal complex;GO:0001673//male germ cell nucleus;GO:0032300//mismatch repair complex;GO:0005712//chiasma,GO:0007130//synaptonemal complex assembly;GO:0006298//mismatch repair;GO:0007144//female meiosis I;GO:0007131//reciprocal meiotic recombination;GO:0008104//protein localization;GO:0007140//male meiosis;GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0003697//single-stranded DNA binding;GO:0003696//satellite DNA binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0030983//mismatched DNA binding;GO:0005515//protein binding;GO:0019237//centromeric DNA binding,K08739//Mismatch repair
27031,0,4,0,0,0,0,0,0,0,0,16,0,NPHP3;nephronophthisis 3 (adolescent),GO:0072372//primary cilium;GO:0005929//cilium,"GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0007368//determination of left/right symmetry;GO:0016055//Wnt signaling pathway;GO:0035469//determination of pancreatic left/right asymmetry;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0003283//atrial septum development;GO:0071910//determination of liver left/right asymmetry;GO:0030324//lung development;GO:0030814//regulation of cAMP metabolic process;GO:0001822//kidney development;GO:0060027//convergent extension involved in gastrulation;GO:0030198//extracellular matrix organization;GO:0060271//cilium morphogenesis;GO:0072189//ureter development;GO:0006629//lipid metabolic process;GO:0071909//determination of stomach left/right asymmetry;GO:0048496//maintenance of organ identity;GO:0071908//determination of intestine left/right asymmetry;GO:0007163//establishment or maintenance of cell polarity;GO:2000167//regulation of planar cell polarity pathway involved in neural tube closure;GO:0060993//kidney morphogenesis;GO:0045494//photoreceptor cell maintenance;GO:0001947//heart looping;GO:0090090//negative regulation of canonical Wnt signaling pathway",GO:0005515//protein binding,K10407//Salmonella infection
27032,0,0,0,86,88,29,44,0,64,0,11,0,"ATP2C1;ATPase, Ca++ transporting, type 2C, member 1",GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0070588//calcium ion transmembrane transport;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034220//ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0007165//signal transduction;GO:0032468//Golgi calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0008152//metabolic process;GO:0031532//actin cytoskeleton reorganization;GO:0030026//cellular manganese ion homeostasis;GO:0006828//manganese ion transport;GO:0032472//Golgi calcium ion transport;GO:0006816//calcium ion transport;GO:0008544//epidermis development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006874//cellular calcium ion homeostasis,GO:0005509//calcium ion binding;GO:0030145//manganese ion binding;GO:0004871//signal transducer activity;GO:0005388//calcium-transporting ATPase activity;GO:0046872//metal ion binding;GO:0015410//manganese-transporting ATPase activity;GO:0005524//ATP binding,K01537//Purine metabolism
27033,0,0,0,0,11,0,5,0,24,0,0,0,ZBTB32;zinc finger and BTB domain containing 32,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000228//nuclear chromosome,GO:0006366//transcription from RNA polymerase II promoter;GO:0042098//T cell proliferation;GO:0030097//hemopoiesis;GO:0001817//regulation of cytokine production;GO:0006281//DNA repair;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
27034,0,82,1,176,270,19,125,0,0,0,328,0,"ACAD8;acyl-CoA dehydrogenase family, member 8",GO:0005759//mitochondrial matrix,"GO:0006355//regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0006574//valine catabolic process;GO:0055114//oxidation-reduction process;GO:0006351//transcription, DNA-templated",GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity,"K11538//Valine, leucine and isoleucine degradation;Metabolic pathways"
27035,0,0,14,0,7,0,0,0,34,0,1,0,NOX1;NADPH oxidase 1,GO:0005769//early endosome;GO:0030054//cell junction;GO:0043020//NADPH oxidase complex;GO:0016021//integral component of membrane;GO:0071438//invadopodium membrane,GO:0006954//inflammatory response;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016477//cell migration;GO:0045730//respiratory burst;GO:0006739//NADP metabolic process;GO:0007165//signal transduction;GO:0045726//positive regulation of integrin biosynthetic process;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0008217//regulation of blood pressure;GO:0042554//superoxide anion generation;GO:0055114//oxidation-reduction process;GO:0034765//regulation of ion transmembrane transport;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0030198//extracellular matrix organization;GO:0008284//positive regulation of cell proliferation;GO:0071455//cellular response to hyperoxia;GO:0042743//hydrogen peroxide metabolic process;GO:0072592//oxygen metabolic process;GO:0001525//angiogenesis;GO:0015992//proton transport;GO:0046330//positive regulation of JNK cascade;GO:0051454//intracellular pH elevation;GO:0006801//superoxide metabolic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0050661//NADP binding;GO:0030171//voltage-gated proton channel activity;GO:0048365//Rac GTPase binding,K08008//Phagosome;Osteoclast differentiation;Leukocyte transendothelial migration
27036,0,0,0,0,0,0,0,0,17,0,0,0,SIGLEC7;sialic acid binding Ig-like lectin 7,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion,GO:0004872//receptor activity;GO:0030246//carbohydrate binding,-
27037,75,1,0,9,27,16,0,71,2,0,1,0,TRMT2A;tRNA methyltransferase 2 homolog A (S. cerevisiae),-,GO:0006396//RNA processing;GO:0001510//RNA methylation,GO:0044822//poly(A) RNA binding;GO:0008173//RNA methyltransferase activity;GO:0000166//nucleotide binding,-
27039,0,0,18,205,218,0,0,0,26,0,89,0,PKD2L2;polycystic kidney disease 2-like 2,GO:0016021//integral component of membrane,GO:0070588//calcium ion transmembrane transport;GO:0050982//detection of mechanical stimulus,GO:0005509//calcium ion binding;GO:0005262//calcium channel activity,-
27040,0,0,0,0,0,0,8,0,0,0,8,0,LAT;linker for activation of T cells,GO:0005886//plasma membrane;GO:0008180//COP9 signalosome;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0042629//mast cell granule;GO:0005911//cell-cell junction;GO:0001772//immunological synapse,GO:0007596//blood coagulation;GO:0043303//mast cell degranulation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0006954//inflammatory response;GO:0030168//platelet activation;GO:0050863//regulation of T cell activation;GO:0007229//integrin-mediated signaling pathway;GO:0006955//immune response;GO:0002260//lymphocyte homeostasis;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0010467//gene expression;GO:0045087//innate immune response;GO:0009967//positive regulation of signal transduction;GO:0007265//Ras protein signal transduction,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0005070//SH3/SH2 adaptor activity,K07362//Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway
27042,0,1,0,21,35,25,18,6,73,0,37,0,DIEXF;digestive organ expansion factor homolog (zebrafish),GO:0005730//nucleolus,GO:0007275//multicellular organismal development,GO:0044822//poly(A) RNA binding,-
27043,0,0,0,0,18,15,8,3,26,0,19,0,"PELP1;proline, glutamate and leucine rich protein 1",GO:0005730//nucleolus;GO:0035327//transcriptionally active chromatin;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071339//MLL1 complex,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071391//cellular response to estrogen stimulus",GO:0003682//chromatin binding;GO:0008134//transcription factor binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K01115//Fc gamma R-mediated phagocytosis;GnRH signaling pathway;Pathways in cancer;Pancreatic cancer;Endocytosis;Glycerophospholipid metabolism;Ether lipid metabolism;Glutamatergic synapse;Metabolic pathways
27044,0,100,2,106,211,28,0,0,27,120,1,0,SND1;staphylococcal nuclease and tudor domain containing 1,GO:0005739//mitochondrion;GO:0097433//dense body;GO:0016442//RISC complex;GO:0005634//nucleus;GO:0042470//melanosome;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,"GO:0016032//viral process;GO:0006351//transcription, DNA-templated;GO:0001649//osteoblast differentiation;GO:0031047//gene silencing by RNA;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004518//nuclease activity;GO:0003712//transcription cofactor activity,K15979//Epstein-Barr virus infection
2705,0,0,0,0,0,0,13,0,12,0,0,0,"GJB1;gap junction protein, beta 1, 32kDa",GO:0005922//connexon complex;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0007267//cell-cell signaling;GO:0016264//gap junction assembly;GO:0051259//protein oligomerization;GO:0008219//cell death;GO:0007399//nervous system development;GO:0061024//membrane organization;GO:0055085//transmembrane transport;GO:0015868//purine ribonucleotide transport;GO:0006810//transport,GO:0042803//protein homodimerization activity;GO:0005243//gap junction channel activity,-
2706,76,0,0,0,0,0,0,0,5,0,0,0,"GJB2;gap junction protein, beta 2, 26kDa",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005922//connexon complex;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016328//lateral plasma membrane,GO:0006810//transport;GO:0007605//sensory perception of sound;GO:0016264//gap junction assembly;GO:0007267//cell-cell signaling;GO:0055085//transmembrane transport;GO:0030539//male genitalia development;GO:0061024//membrane organization,GO:0005243//gap junction channel activity,-
27063,12,0,0,0,0,0,31,87,16,0,0,0,ANKRD1;ankyrin repeat domain 1 (cardiac muscle),GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0031674//I band;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0071407//cellular response to organic cyclic compound;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035994//response to muscle stretch;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0035690//cellular response to drug;GO:0044281//small molecule metabolic process;GO:0071456//cellular response to hypoxia;GO:2000279//negative regulation of DNA biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0035914//skeletal muscle cell differentiation;GO:0071260//cellular response to mechanical stimulus;GO:0043065//positive regulation of apoptotic process;GO:0071347//cellular response to interleukin-1;GO:0045214//sarcomere organization;GO:0055008//cardiac muscle tissue morphogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0010976//positive regulation of neuron projection development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050714//positive regulation of protein secretion",GO:0005515//protein binding;GO:0031432//titin binding;GO:0002039//p53 binding;GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0042826//histone deacetylase binding;GO:0003714//transcription corepressor activity;GO:0070412//R-SMAD binding,-
27065,0,0,1,8,19,0,0,0,18,0,17,0,NSG1;neuron specific gene family member 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0007212//dopamine receptor signaling pathway;GO:0048268//clathrin coat assembly,GO:0032051//clathrin light chain binding,K15493//Dopaminergic synapse
27067,100,0,0,9,61,14,0,0,33,0,12,0,STAU2;staufen double-stranded RNA binding protein 2,GO:0005874//microtubule;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0006810//transport,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003725//double-stranded RNA binding,K08860//Herpes simplex infection;Protein processing in endoplasmic reticulum;Alzheimer's disease;Hepatitis C;Measles;Epstein-Barr virus infection;Influenza A
27068,18,1,0,13,59,0,4,0,1,0,0,0,PPA2;pyrophosphatase (inorganic) 2,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome,GO:0016311//dephosphorylation;GO:0071344//diphosphate metabolic process;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0004722//protein serine/threonine phosphatase activity;GO:0000287//magnesium ion binding;GO:0004427//inorganic diphosphatase activity,K01507//Oxidative phosphorylation
27069,186,54,2,34,135,2,1,0,9,1,6,0,GHITM;growth hormone inducible transmembrane protein,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,GO:0006915//apoptotic process,GO:0005515//protein binding,K04514//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Wnt signaling pathway;Focal adhesion;Pathogenic Escherichia coli infection;Salmonella infection;Axon guidance;Chemokine signaling pathway;TGF-beta signaling pathway;Shigellosis;Leukocyte transendothelial migration
2707,0,0,0,0,0,0,0,0,40,0,5,0,"GJB3;gap junction protein, beta 3, 31kDa",GO:0005737//cytoplasm;GO:0005922//connexon complex;GO:0005921//gap junction;GO:0016021//integral component of membrane,GO:0001890//placenta development;GO:0055085//transmembrane transport;GO:0043588//skin development;GO:0001701//in utero embryonic development;GO:0007605//sensory perception of sound;GO:0007154//cell communication,GO:0005243//gap junction channel activity,-
27071,0,0,0,0,0,0,12,0,28,0,0,0,DAPP1;dual adaptor of phosphotyrosine and 3-phosphoinositides,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0006470//protein dephosphorylation;GO:0007165//signal transduction,"GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005543//phospholipid binding",K12229//B cell receptor signaling pathway
27072,0,1,1,44,145,36,78,0,76,0,4,0,VPS41;vacuolar protein sorting 41 homolog (S. cerevisiae),GO:0005798//Golgi-associated vesicle;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0005770//late endosome;GO:0005769//early endosome,GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0048193//Golgi vesicle transport,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
27074,73,0,45,0,0,0,0,0,22,0,3,0,LAMP3;lysosomal-associated membrane protein 3,GO:0005765//lysosomal membrane;GO:0097233//alveolar lamellar body membrane;GO:0016021//integral component of membrane,GO:0008283//cell proliferation;GO:0002376//immune system process,-,K06562//Lysosome
27076,0,0,1,0,0,0,0,0,26,1,13,0,LYPD3;LY6/PLAUR domain containing 3,GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0046658//anchored component of plasma membrane,GO:0007160//cell-matrix adhesion;GO:0006928//cellular component movement,GO:0043236//laminin binding,K03985//Complement and coagulation cascades
27077,0,0,50,0,0,0,1,0,0,0,3,0,B9D1;B9 protein domain 1,GO:0035869//ciliary transition zone;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005813//centrosome;GO:0036038//TCTN-B9D complex;GO:0005737//cytoplasm,GO:0043010//camera-type eye development;GO:0007224//smoothened signaling pathway;GO:0032880//regulation of protein localization;GO:0001701//in utero embryonic development;GO:0060563//neuroepithelial cell differentiation;GO:0060271//cilium morphogenesis;GO:0042384//cilium assembly;GO:0001944//vasculature development;GO:0042733//embryonic digit morphogenesis,GO:0008158//hedgehog receptor activity,-
27079,27,0,1,1,0,0,26,0,29,0,0,0,RPUSD2;RNA pseudouridylate synthase domain containing 2,-,GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0044822//poly(A) RNA binding,K01718//Pyrimidine metabolism
27085,0,0,0,0,0,23,0,0,50,0,2,0,MTBP;MDM2 binding protein,GO:0000785//chromatin;GO:0000776//kinetochore,GO:0071174//mitotic spindle checkpoint;GO:0007089//traversing start control point of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0007050//cell cycle arrest;GO:0034501//protein localization to kinetochore,-,-
27086,69,51,0,33,179,5,47,5,37,1,21,0,FOXP1;forkhead box P1,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
27087,0,23,0,4,0,0,0,0,4,0,24,0,"B3GAT1;beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation,"GO:0046872//metal ion binding;GO:0015018//galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity",K00735//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
27089,0,26,1,9,53,0,0,0,19,0,0,0,"UQCRQ;ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0070469//respiratory chain,GO:0021680//cerebellar Purkinje cell layer development;GO:0021854//hypothalamus development;GO:0021794//thalamus development;GO:0021860//pyramidal neuron development;GO:0021548//pons development;GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0030901//midbrain development;GO:0044237//cellular metabolic process;GO:0021539//subthalamus development;GO:0044281//small molecule metabolic process;GO:0021766//hippocampus development,GO:0008121//ubiquinol-cytochrome-c reductase activity,K00418//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Cardiac muscle contraction
2709,0,0,0,0,0,16,0,0,13,0,0,0,"GJB5;gap junction protein, beta 5, 31.1kDa",GO:0005922//connexon complex;GO:0016021//integral component of membrane,GO:0007154//cell communication;GO:0008544//epidermis development;GO:0060708//spongiotrophoblast differentiation;GO:0060713//labyrinthine layer morphogenesis,-,-
27090,67,0,0,0,0,0,0,0,0,235,0,0,"ST6GALNAC4;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0006664//glycolipid metabolic process;GO:0097503//sialylation;GO:0044267//cellular protein metabolic process,"GO:0047290//(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity;GO:0008373//sialyltransferase activity",K03374//Glycosphingolipid biosynthesis - ganglio series;Metabolic pathways
27091,0,0,0,0,0,0,0,0,30,0,0,0,"CACNG5;calcium channel, voltage-dependent, gamma subunit 5",GO:0014069//postsynaptic density;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0006810//transport;GO:0070588//calcium ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity;GO:0015075//ion transmembrane transporter activity,K04870//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Dilated cardiomyopathy;Cardiac muscle contraction
27092,0,0,0,4,1,1,3,0,0,0,6,325,"CACNG4;calcium channel, voltage-dependent, gamma subunit 4",GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex,GO:0070588//calcium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006810//transport;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0051899//membrane depolarization;GO:0019226//transmission of nerve impulse,GO:0005245//voltage-gated calcium channel activity,K04869//Cardiac muscle contraction;Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway
27094,0,0,0,0,0,0,18,0,24,30,9,0,"KCNMB3;potassium large conductance calcium-activated channel, subfamily M beta member 3",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane,GO:0007596//blood coagulation;GO:0001508//action potential;GO:0006813//potassium ion transport;GO:0019228//neuronal action potential;GO:0071805//potassium ion transmembrane transport;GO:0005513//detection of calcium ion;GO:0007268//synaptic transmission,GO:0015459//potassium channel regulator activity;GO:0015269//calcium-activated potassium channel activity,K04939//Vascular smooth muscle contraction
27095,0,0,0,1,9,0,0,0,29,0,0,42,TRAPPC3;trafficking protein particle complex 3,GO:0030008//TRAPP complex;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane,GO:0006888//ER to Golgi vesicle-mediated transport,GO:0005515//protein binding,-
27097,0,0,0,9,0,0,1,0,35,0,0,0,"TAF5L;TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa",GO:0033276//transcription factor TFTC complex;GO:0030914//STAGA complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0006366//transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K03130//Basal transcription factors;Herpes simplex infection
27098,0,0,0,0,0,0,0,0,17,0,3,0,CLUL1;clusterin-like 1 (retinal),GO:0005576//extracellular region,GO:0008219//cell death,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series
271,0,0,0,0,0,2,0,12,7,69,0,0,AMPD2;adenosine monophosphate deaminase 2,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0032264//IMP salvage;GO:0006144//purine nucleobase metabolic process;GO:0043101//purine-containing compound salvage;GO:0097009//energy homeostasis,GO:0046872//metal ion binding;GO:0003876//AMP deaminase activity,K01490//Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
2710,0,0,0,5,43,0,23,0,66,181,0,0,GK;glycerol kinase,GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane,GO:0046167//glycerol-3-phosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0042593//glucose homeostasis;GO:0006071//glycerol metabolic process;GO:0044255//cellular lipid metabolic process;GO:0016310//phosphorylation;GO:0019432//triglyceride biosynthetic process;GO:0019563//glycerol catabolic process;GO:0006641//triglyceride metabolic process,GO:0005515//protein binding;GO:0004370//glycerol kinase activity;GO:0005524//ATP binding,K00864//Plant-pathogen interaction;Glycerolipid metabolism;PPAR signaling pathway;Metabolic pathways
27101,0,62,72,56,231,30,69,0,20,0,0,0,CACYBP;calcyclin binding protein,GO:0043005//neuron projection;GO:0005641//nuclear envelope lumen;GO:0030877//beta-catenin destruction complex;GO:0070062//extracellular vesicular exosome;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0007568//aging;GO:0055007//cardiac muscle cell differentiation;GO:0060416//response to growth hormone;GO:0071277//cellular response to calcium ion;GO:0045740//positive regulation of DNA replication;GO:0060548//negative regulation of cell death,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K04507//Wnt signaling pathway
27102,0,140,148,156,269,0,0,181,15,0,261,0,EIF2AK1;eukaryotic translation initiation factor 2-alpha kinase 1,GO:0005737//cytoplasm,GO:0008285//negative regulation of cell proliferation;GO:0009605//response to external stimulus;GO:0006950//response to stress;GO:0046501//protoporphyrinogen IX metabolic process;GO:0045993//negative regulation of translational initiation by iron;GO:0046777//protein autophosphorylation;GO:0010999//regulation of eIF2 alpha phosphorylation by heme;GO:0046986//negative regulation of hemoglobin biosynthetic process,GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0020037//heme binding,K08860//Herpes simplex infection;Protein processing in endoplasmic reticulum;Alzheimer's disease;Hepatitis C;Measles;Epstein-Barr virus infection;Influenza A
27106,61,0,0,0,0,0,18,0,35,0,15,0,ARRDC2;arrestin domain containing 2,GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle,GO:0007165//signal transduction,-,-
27107,0,113,27,58,141,0,7,152,70,0,182,2,ZBTB11;zinc finger and BTB domain containing 11,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
27109,0,0,0,0,4,0,0,0,0,0,0,0,"ATP5S;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)","GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0005743//mitochondrial inner membrane",GO:1902600//hydrogen ion transmembrane transport;GO:0015992//proton transport;GO:0006754//ATP biosynthetic process,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0046872//metal ion binding,-
27112,0,0,0,0,12,0,2,0,3,0,0,0,"FAM155B;family with sequence similarity 155, member B",GO:0016021//integral component of membrane,-,-,-
27113,0,0,0,0,0,5,4,0,0,0,0,0,BBC3;BCL2 binding component 3,GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0006915//apoptotic process;GO:0008340//determination of adult lifespan;GO:0045926//negative regulation of growth;GO:0097190//apoptotic signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0034976//response to endoplasmic reticulum stress;GO:0001836//release of cytochrome c from mitochondria;GO:0043525//positive regulation of neuron apoptotic process;GO:0051209//release of sequestered calcium ion into cytosol;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0097194//execution phase of apoptosis;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0032464//positive regulation of protein homooligomerization;GO:0071456//cellular response to hypoxia,GO:0005515//protein binding,K10132//p53 signaling pathway;Measles;Huntington's disease
27115,0,0,0,0,8,0,29,0,71,0,0,0,PDE7B;phosphodiesterase 7B,GO:0005829//cytosol,GO:0006198//cAMP catabolic process;GO:0007268//synaptic transmission;GO:0007165//signal transduction,"GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0046872//metal ion binding",K01120//Purine metabolism;Morphine addiction
2712,0,0,0,0,0,23,0,0,25,0,0,0,GK2;glycerol kinase 2,GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome,GO:0019563//glycerol catabolic process;GO:0016310//phosphorylation;GO:0006072//glycerol-3-phosphate metabolic process,GO:0005524//ATP binding;GO:0004370//glycerol kinase activity,K00864//Metabolic pathways;PPAR signaling pathway;Glycerolipid metabolism;Plant-pathogen interaction
27120,0,0,0,0,1,0,0,0,0,0,0,0,DKKL1;dickkopf-like 1,GO:0005615//extracellular space,GO:0045600//positive regulation of fat cell differentiation;GO:0007165//signal transduction;GO:0009653//anatomical structure morphogenesis,GO:0004871//signal transducer activity,-
27121,0,0,0,0,0,0,0,0,0,0,15,0,DKK4;dickkopf WNT signaling pathway inhibitor 4,GO:0005576//extracellular region,GO:0007275//multicellular organismal development;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway,-,K02165//Wnt signaling pathway
27122,0,0,0,0,0,0,0,0,0,0,4,0,DKK3;dickkopf WNT signaling pathway inhibitor 3,GO:0005615//extracellular space,"GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:2000065//negative regulation of cortisol biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0016055//Wnt signaling pathway;GO:0030325//adrenal gland development",-,K02165//Wnt signaling pathway
27123,0,0,0,0,13,0,9,0,0,0,1,0,DKK2;dickkopf WNT signaling pathway inhibitor 2,GO:0005615//extracellular space,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007275//multicellular organismal development,-,K02165//Wnt signaling pathway
27124,0,0,0,0,0,0,28,47,8,0,5,0,INPP5J;inositol polyphosphate-5-phosphatase J,GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0043198//dendritic shaft,GO:0006644//phospholipid metabolic process;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0044281//small molecule metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0031115//negative regulation of microtubule polymerization,"GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0017124//SH3 domain binding;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity",K01106//Metabolic pathways;Insulin signaling pathway;Phosphatidylinositol signaling system;Inositol phosphate metabolism
27125,0,179,1,162,379,14,82,2,11,0,2,0,"AFF4;AF4/FMR2 family, member 4",GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0035327//transcriptionally active chromatin;GO:0008023//transcription elongation factor complex;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0007286//spermatid development;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
27127,0,11,0,21,0,12,57,0,31,44,7,0,SMC1B;structural maintenance of chromosomes 1B,"GO:0030893//meiotic cohesin complex;GO:0000775//chromosome, centromeric region;GO:0000800//lateral element;GO:0034991//nuclear meiotic cohesin complex",GO:0007126//meiotic nuclear division;GO:0007062//sister chromatid cohesion,GO:0005524//ATP binding;GO:0003677//DNA binding,K06636//Cell cycle - yeast;Cell cycle;Oocyte meiosis;Meiosis - yeast
27128,101,0,0,0,0,14,39,0,12,2,0,0,CYTH4;cytohesin 4,GO:0005802//trans-Golgi network;GO:0005886//plasma membrane,GO:0030155//regulation of cell adhesion;GO:0032012//regulation of ARF protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0043547//positive regulation of GTPase activity,GO:0008289//lipid binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
27129,0,0,0,0,0,23,1,0,21,0,31,0,"HSPB7;heat shock 27kDa protein family, member 7 (cardiovascular)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0015629//actin cytoskeleton;GO:0005739//mitochondrion,GO:0008016//regulation of heart contraction;GO:0006986//response to unfolded protein,GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0031005//filamin binding,-
2713,0,0,0,0,0,0,15,0,28,0,0,0,GK3P;glycerol kinase 3 pseudogene,-,-,-,K00864//Metabolic pathways;PPAR signaling pathway;Glycerolipid metabolism;Plant-pathogen interaction
27130,0,0,0,14,0,41,0,0,6,0,11,0,INVS;inversin,GO:0005929//cilium;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005874//microtubule,GO:0031016//pancreas development;GO:0009791//post-embryonic development;GO:0001822//kidney development;GO:0016055//Wnt signaling pathway;GO:0060971//embryonic heart tube left/right pattern formation;GO:0090090//negative regulation of canonical Wnt signaling pathway,GO:0005516//calmodulin binding;GO:0005515//protein binding,-
27131,0,142,1,58,123,0,0,0,8,91,0,0,SNX5;sorting nexin 5,GO:0070685//macropinocytic cup;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0001726//ruffle;GO:0030659//cytoplasmic vesicle membrane;GO:0031901//early endosome membrane;GO:0001891//phagocytic cup;GO:0031313//extrinsic component of endosome membrane,GO:0006907//pinocytosis;GO:0006886//intracellular protein transport,GO:0035091//phosphatidylinositol binding,-
27132,0,0,0,0,0,0,0,0,13,142,0,343,CPNE7;copine VII,GO:0070062//extracellular vesicular exosome,GO:0006810//transport;GO:0006629//lipid metabolic process,GO:0005215//transporter activity,K06491//Prion diseases;Cell adhesion molecules (CAMs)
27133,0,0,0,0,0,0,28,0,26,0,0,0,"KCNH5;potassium voltage-gated channel, subfamily H (eag-related), member 5",GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005887//integral component of plasma membrane,GO:0042391//regulation of membrane potential;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0023014//signal transduction by phosphorylation;GO:0071805//potassium ion transmembrane transport;GO:0000160//phosphorelay signal transduction system;GO:0010389//regulation of G2/M transition of mitotic cell cycle,GO:0005516//calmodulin binding;GO:0000155//phosphorelay sensor kinase activity;GO:0005249//voltage-gated potassium channel activity,-
27134,45,15,1,0,26,10,4,59,70,0,36,0,TJP3;tight junction protein 3,GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005923//tight junction,GO:2000045//regulation of G1/S transition of mitotic cell cycle,GO:0005515//protein binding,K06097//Tight junction
27136,0,0,0,0,0,0,16,0,99,0,0,0,MORC1;MORC family CW-type zinc finger 1,GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,GO:0008270//zinc ion binding,-
27141,0,430,528,781,1208,0,71,754,65,0,1304,0,CIDEB;cell death-inducing DFFA-like effector b,GO:0005829//cytosol;GO:0005811//lipid particle,GO:0042981//regulation of apoptotic process;GO:0097194//execution phase of apoptosis;GO:0006915//apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage,GO:0005515//protein binding;GO:0042802//identical protein binding,K04297//Neuroactive ligand-receptor interaction;Calcium signaling pathway
27143,52,0,0,0,0,1,28,0,124,0,5,0,"PALD1;phosphatase domain containing, paladin 1",GO:0005829//cytosol,-,GO:0005515//protein binding,-
27145,0,0,0,0,0,0,37,1,8,0,0,0,FILIP1;filamin A interacting protein 1,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K12478//Tuberculosis;Phagosome;Endocytosis;K11447//Transcriptional misregulation in cancer
27146,0,0,0,108,46,25,0,0,51,75,47,0,"FAM184B;family with sequence similarity 184, member B",-,-,-,K06102//Tight junction
27147,0,0,0,0,0,0,0,0,11,0,8,154,DENND2A;DENN/MADD domain containing 2A,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton,"GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi",GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
27148,0,0,0,0,0,18,34,0,52,0,0,0,STK36;serine/threonine kinase 36,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0009791//post-embryonic development;GO:0003351//epithelial cilium movement;GO:0007228//positive regulation of hh target transcription factor activity;GO:0042384//cilium assembly;GO:0006468//protein phosphorylation;GO:0007420//brain development;GO:0045880//positive regulation of smoothened signaling pathway,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0004674//protein serine/threonine kinase activity,K06228//Pathways in cancer;Hedgehog signaling pathway;Basal cell carcinoma
27151,8,0,0,4,0,39,138,72,30,0,37,0,"CPAMD8;C3 and PZP-like, alpha-2-macroglobulin domain containing 8",GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03910//Complement and coagulation cascades
27152,1,0,0,0,6,0,26,0,32,0,1,0,INTU;inturned planar cell polarity protein,GO:0005737//cytoplasm;GO:0009986//cell surface,GO:0051782//negative regulation of cell division;GO:0060173//limb development;GO:0031069//hair follicle morphogenesis;GO:0030216//keratinocyte differentiation;GO:0021513//spinal cord dorsal/ventral patterning;GO:0045880//positive regulation of smoothened signaling pathway;GO:0010839//negative regulation of keratinocyte proliferation;GO:0007399//nervous system development;GO:0042384//cilium assembly;GO:0008589//regulation of smoothened signaling pathway,-,-
27153,0,0,0,14,4,35,17,0,8,1,0,328,ZNF777;zinc finger protein 777,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
27154,0,1,1,25,61,0,0,16,41,0,16,0,"BRPF3;bromodomain and PHD finger containing, 3",GO:0070776//MOZ/MORF histone acetyltransferase complex;GO:0005576//extracellular region;GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0043966//histone H3 acetylation;GO:0002576//platelet degranulation,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
27156,0,0,0,0,0,0,0,0,33,0,14,0,RTDR1;rhabdoid tumor deletion region gene 1,-,-,-,-
27158,0,1,0,0,1,11,60,0,14,42,0,0,NDOR1;NADPH dependent diflavin oxidoreductase 1,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton,GO:0008219//cell death;GO:0055114//oxidation-reduction process;GO:0016226//iron-sulfur cluster assembly;GO:0036245//cellular response to menadione;GO:0044281//small molecule metabolic process,"GO:0050661//NADP binding;GO:0010181//FMN binding;GO:0005506//iron ion binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0005515//protein binding;GO:0016491//oxidoreductase activity",-
27159,0,0,39,0,0,17,45,0,0,190,12,0,"CHIA;chitinase, acidic",GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0000272//polysaccharide catabolic process;GO:0006955//immune response;GO:0006915//apoptotic process;GO:0001101//response to acid chemical;GO:0090197//positive regulation of chemokine secretion;GO:0007586//digestion;GO:0009620//response to fungus;GO:0006037//cell wall chitin metabolic process;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0006032//chitin catabolic process,GO:0030246//carbohydrate binding;GO:0004568//chitinase activity;GO:0003796//lysozyme activity;GO:0008061//chitin binding;GO:0019900//kinase binding,K01183//Metabolic pathways;Starch and sucrose metabolism;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
27160,0,0,0,0,0,6,0,0,0,0,0,0,"INGX;inhibitor of growth family, X-linked, pseudogene",-,-,-,K11447//Transcriptional misregulation in cancer
27161,0,0,0,0,25,15,0,0,54,12,8,0,AGO2;argonaute RISC catalytic component 2,GO:0035068//micro-ribonucleoprotein complex;GO:0005844//polysome;GO:0005845//mRNA cap binding complex;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0005829//cytosol;GO:0005634//nucleus;GO:0016442//RISC complex,"GO:0045087//innate immune response;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0035279//mRNA cleavage involved in gene silencing by miRNA;GO:0031047//gene silencing by RNA;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006412//translation;GO:0006351//transcription, DNA-templated;GO:0048015//phosphatidylinositol-mediated signaling;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0045947//negative regulation of translational initiation;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0009791//post-embryonic development;GO:0006413//translational initiation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0031054//pre-miRNA processing;GO:0038095//Fc-epsilon receptor signaling pathway","GO:0003729//mRNA binding;GO:0000340//RNA 7-methylguanosine cap binding;GO:0070551//endoribonuclease activity, cleaving siRNA-paired mRNA;GO:0004521//endoribonuclease activity;GO:0035197//siRNA binding;GO:0035198//miRNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003743//translation initiation factor activity",-
27163,93,0,1,13,22,0,0,0,20,2,5,0,NAAA;N-acylethanolamine acid amidase,GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0005737//cytoplasm,GO:0006629//lipid metabolic process,"GO:0008134//transcription factor binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds",-
27164,1,0,0,0,16,0,76,81,95,0,6,0,SALL3;spalt-like transcription factor 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0045879//negative regulation of smoothened signaling pathway;GO:0035136//forelimb morphogenesis;GO:0006351//transcription, DNA-templated;GO:0035137//hindlimb morphogenesis;GO:0021891//olfactory bulb interneuron development",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
27165,0,0,48,20,64,22,14,0,36,4,23,0,"GLS2;glutaminase 2 (liver, mitochondrial)",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0014047//glutamate secretion;GO:0008652//cellular amino acid biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0007269//neurotransmitter secretion;GO:0006520//cellular amino acid metabolic process;GO:0007268//synaptic transmission;GO:0006541//glutamine metabolic process;GO:0042981//regulation of apoptotic process;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0004359//glutaminase activity,"K01425//D-Glutamine and D-glutamate metabolism;Pyrimidine metabolism;GABAergic synapse;Microbial metabolism in diverse environments;Proximal tubule bicarbonate reclamation;Nitrogen metabolism;Arginine and proline metabolism;Two-component system;Glutamatergic synapse;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Oxidative phosphorylation"
27166,0,0,0,0,2,8,0,0,27,0,0,0,PRELID1;PRELI domain containing 1,GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005634//nucleus,GO:0010950//positive regulation of endopeptidase activity;GO:0045580//regulation of T cell differentiation;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0070234//positive regulation of T cell apoptotic process;GO:2001140//positive regulation of phospholipid transport;GO:0043066//negative regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:0015914//phospholipid transport;GO:0006955//immune response;GO:0051881//regulation of mitochondrial membrane potential;GO:0097035//regulation of membrane lipid distribution;GO:0006915//apoptotic process;GO:1901857//positive regulation of cellular respiration;GO:0010917//negative regulation of mitochondrial membrane potential,GO:0005515//protein binding;GO:1990050//phosphatidic acid transporter activity,-
2717,0,0,0,5,0,0,19,0,40,15,8,0,"GLA;galactosidase, alpha",GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0006687//glycosphingolipid metabolic process;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0016139//glycoside catabolic process;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0046477//glycosylceramide catabolic process;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0009311//oligosaccharide metabolic process,GO:0016787//hydrolase activity;GO:0003824//catalytic activity;GO:0005102//receptor binding;GO:0052692//raffinose alpha-galactosidase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004557//alpha-galactosidase activity;GO:0016936//galactoside binding,K01189//Glycosphingolipid biosynthesis - globo series;Glycerolipid metabolism;Galactose metabolism;Lysosome;Sphingolipid metabolism
27173,35,0,38,23,48,0,30,0,11,0,16,0,"SLC39A1;solute carrier family 39 (zinc transporter), member 1",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0071577//zinc ion transmembrane transport;GO:0006812//cation transport;GO:0055085//transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity;GO:0005102//receptor binding,-
27175,0,0,2,0,0,0,0,0,0,0,0,0,"TUBG2;tubulin, gamma 2",GO:0000242//pericentriolar material;GO:0005881//cytoplasmic microtubule;GO:0005829//cytosol;GO:0000930//gamma-tubulin complex;GO:0005874//microtubule;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton,GO:0006184//GTP catabolic process;GO:0007020//microtubule nucleation;GO:0031122//cytoplasmic microtubule organization;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005198//structural molecule activity,-
27177,0,0,0,0,0,0,0,0,10,0,0,0,"IL36B;interleukin 36, beta",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0045582//positive regulation of T cell differentiation;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0032755//positive regulation of interleukin-6 production,GO:0005149//interleukin-1 receptor binding;GO:0005125//cytokine activity,-
27178,0,0,0,0,0,0,36,0,0,0,0,0,IL37;interleukin 37,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005634//nucleus,GO:0006955//immune response;GO:0006954//inflammatory response,GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding,-
27180,0,27,0,0,0,26,8,0,31,0,0,0,SIGLEC9;sialic acid binding Ig-like lectin 9,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007166//cell surface receptor signaling pathway,GO:0030246//carbohydrate binding,-
27181,0,0,0,0,0,0,45,0,49,0,0,0,SIGLEC8;sialic acid binding Ig-like lectin 8,GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding,-
27183,0,223,48,225,182,23,8,173,40,0,352,0,VPS4A;vacuolar protein sorting 4 homolog A (S. cerevisiae),GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0000815//ESCRT III complex;GO:0030496//midbody;GO:0031902//late endosome membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0031565//cytokinesis checkpoint;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0032466//negative regulation of cytokinesis;GO:0016192//vesicle-mediated transport;GO:0016032//viral process;GO:0000910//cytokinesis;GO:0006200//ATP catabolic process;GO:0019058//viral life cycle;GO:0009838//abscission,"GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0042623//ATPase activity, coupled;GO:0019904//protein domain specific binding",K12196//Endocytosis
27185,0,0,0,0,0,9,44,0,97,0,0,0,DISC1;disrupted in schizophrenia 1,GO:0045211//postsynaptic membrane;GO:0005739//mitochondrion;GO:0036064//ciliary basal body;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005874//microtubule;GO:0005813//centrosome,GO:0051560//mitochondrial calcium ion homeostasis;GO:0090128//regulation of synapse maturation;GO:0010975//regulation of neuron projection development;GO:0031929//TOR signaling;GO:0021799//cerebral cortex radially oriented cell migration;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0002052//positive regulation of neuroblast proliferation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0000226//microtubule cytoskeleton organization;GO:0034613//cellular protein localization;GO:0021846//cell proliferation in forebrain;GO:0001764//neuron migration;GO:0060070//canonical Wnt signaling pathway,GO:0005515//protein binding,K09592//Pathways in cancer;Renal cell carcinoma;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
27189,0,0,0,0,0,0,1,0,11,0,0,0,IL17C;interleukin 17C,GO:0005615//extracellular space,GO:0030223//neutrophil differentiation;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0007166//cell surface receptor signaling pathway,GO:0005125//cytokine activity,-
2719,0,0,0,0,0,1,0,0,0,0,13,0,GPC3;glypican 3,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen;GO:0046658//anchored component of plasma membrane;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane,"GO:0001523//retinoid metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0072180//mesonephric duct morphogenesis;GO:0044281//small molecule metabolic process;GO:0035116//embryonic hindlimb morphogenesis;GO:0006024//glycosaminoglycan biosynthetic process;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0009653//anatomical structure morphogenesis;GO:0046326//positive regulation of glucose import;GO:0007603//phototransduction, visible light;GO:0010171//body morphogenesis;GO:0010466//negative regulation of peptidase activity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0045879//negative regulation of smoothened signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0072203//cell proliferation involved in metanephros development;GO:0060976//coronary vasculature development;GO:0005975//carbohydrate metabolic process;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0030203//glycosaminoglycan metabolic process;GO:0009948//anterior/posterior axis specification;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0030324//lung development;GO:0030316//osteoclast differentiation;GO:0030282//bone mineralization;GO:0045926//negative regulation of growth;GO:0045807//positive regulation of endocytosis;GO:0045880//positive regulation of smoothened signaling pathway",GO:0005515//protein binding;GO:0060422//peptidyl-dipeptidase inhibitor activity;GO:0043395//heparan sulfate proteoglycan binding,-
27190,0,0,0,0,0,19,0,56,9,0,0,0,IL17B;interleukin 17B,GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0007267//cell-cell signaling;GO:0006955//immune response,GO:0005125//cytokine activity,K05490//Cytokine-cytokine receptor interaction
27197,0,0,0,0,0,0,25,0,10,0,0,0,GPR82;G protein-coupled receptor 82,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
27198,0,0,0,0,0,10,0,0,30,0,16,0,HCAR1;hydroxycarboxylic acid receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0032355//response to estradiol;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
27199,0,0,0,0,22,0,0,0,2,0,8,0,OXGR1;oxoglutarate (alpha-ketoglutarate) receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
272,2,0,0,13,41,78,0,1,39,0,19,0,AMPD3;adenosine monophosphate deaminase 3,GO:0005829//cytosol,GO:0097009//energy homeostasis;GO:0043101//purine-containing compound salvage;GO:0006196//AMP catabolic process;GO:0044281//small molecule metabolic process;GO:0046031//ADP metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0032264//IMP salvage;GO:0046034//ATP metabolic process,GO:0003876//AMP deaminase activity;GO:0046872//metal ion binding,K01490//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites
2720,0,0,0,10,1,21,0,36,6,0,5,0,"GLB1;galactosidase, beta 1",GO:0043202//lysosomal lumen;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0019388//galactose catabolic process;GO:0042340//keratan sulfate catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006027//glycosaminoglycan catabolic process,GO:0016936//galactoside binding;GO:0004565//beta-galactosidase activity;GO:0005515//protein binding,K12309//Other glycan degradation;Glycosphingolipid biosynthesis - ganglio series;Glycosaminoglycan degradation;Galactose metabolism;Metabolic pathways;Lysosome;Sphingolipid metabolism
27201,0,0,0,0,0,8,0,41,9,0,0,0,GPR78;G protein-coupled receptor 78,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
27229,72,237,250,180,392,20,0,0,22,0,101,0,"TUBGCP4;tubulin, gamma complex associated protein 4",GO:0016020//membrane;GO:0005829//cytosol;GO:0008274//gamma-tubulin ring complex;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005813//centrosome,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006461//protein complex assembly;GO:0007020//microtubule nucleation,GO:0005200//structural constituent of cytoskeleton,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer
27230,0,171,31,184,580,0,0,0,46,0,0,0,SERP1;stress-associated endoplasmic reticulum protein 1,GO:0005881//cytoplasmic microtubule;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005840//ribosome;GO:0005789//endoplasmic reticulum membrane,GO:0006950//response to stress;GO:0044267//cellular protein metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0001501//skeletal system development;GO:0006006//glucose metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0009791//post-embryonic development;GO:0032024//positive regulation of insulin secretion;GO:0010259//multicellular organismal aging;GO:0045727//positive regulation of translation;GO:0006486//protein glycosylation;GO:0015031//protein transport;GO:0046622//positive regulation of organ growth;GO:0007009//plasma membrane organization;GO:0060124//positive regulation of growth hormone secretion;GO:0048644//muscle organ morphogenesis;GO:0006464//cellular protein modification process,-,-
27231,0,0,0,0,0,10,8,0,3,0,1,0,NMRK2;nicotinamide riboside kinase 2,GO:0005622//intracellular,GO:0016310//phosphorylation;GO:0009435//NAD biosynthetic process;GO:0045662//negative regulation of myoblast differentiation,GO:0050262//ribosylnicotinamide kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K10524//Nicotinate and nicotinamide metabolism
27232,0,21,1,7,1,22,0,0,0,0,10,0,GNMT;glycine N-methyltransferase,GO:0005737//cytoplasm,GO:0006464//cellular protein modification process;GO:0006730//one-carbon metabolic process;GO:0051289//protein homotetramerization;GO:0032259//methylation;GO:0006555//methionine metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0046500//S-adenosylmethionine metabolic process;GO:0005977//glycogen metabolic process,GO:0017174//glycine N-methyltransferase activity;GO:0005542//folic acid binding;GO:0005515//protein binding;GO:0016594//glycine binding,"K00552//Glycine, serine and threonine metabolism"
27235,0,0,0,7,10,0,24,0,15,0,0,0,COQ2;coenzyme Q2 4-hydroxybenzoate polyprenyltransferase,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006744//ubiquinone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0006071//glycerol metabolic process;GO:0008299//isoprenoid biosynthetic process,GO:0002083//4-hydroxybenzoate decaprenyltransferase activity;GO:0047293//4-hydroxybenzoate nonaprenyltransferase activity,K06125//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
27236,0,42,0,22,110,0,0,0,10,0,0,66,ARFIP1;ADP-ribosylation factor interacting protein 1,GO:0005829//cytosol;GO:0000139//Golgi membrane,GO:0006886//intracellular protein transport;GO:0050708//regulation of protein secretion,GO:0042802//identical protein binding;GO:0019904//protein domain specific binding,-
27237,0,0,0,0,0,0,2,0,19,0,12,0,ARHGEF16;Rho guanine nucleotide exchange factor (GEF) 16,GO:0005829//cytosol,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0032864//activation of Cdc42 GTPase activity;GO:0060326//cell chemotaxis;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032863//activation of Rac GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0030165//PDZ domain binding;GO:0030971//receptor tyrosine kinase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017048//Rho GTPase binding,K13744//Bacterial invasion of epithelial cells
27238,0,14,0,12,2,0,0,0,23,0,0,0,GPKOW;G patch domain and KOW motifs,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0005515//protein binding;GO:0003676//nucleic acid binding,-
27239,0,0,1,0,5,13,0,0,22,0,32,0,GPR162;G protein-coupled receptor 162,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,K01689//Glycolysis / Gluconeogenesis;Methane metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;RNA degradation;Microbial metabolism in diverse environments
27240,0,0,0,0,0,0,8,0,2,0,6,0,SIT1;signaling threshold regulating transmembrane adaptor 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0002376//immune system process;GO:0007165//signal transduction;GO:0050863//regulation of T cell activation,GO:0005515//protein binding;GO:0019900//kinase binding;GO:0042169//SH2 domain binding,-
27241,110,0,0,34,5,0,24,0,37,0,12,0,BBS9;Bardet-Biedl syndrome 9,GO:0005929//cilium;GO:0034464//BBSome;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0005815//microtubule organizing center,GO:0045444//fat cell differentiation;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0015031//protein transport,GO:0005515//protein binding,-
27242,0,0,1,0,0,12,23,0,12,0,0,0,"TNFRSF21;tumor necrosis factor receptor superfamily, member 21",GO:0005886//plasma membrane;GO:0030424//axon;GO:0031226//intrinsic component of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0051402//neuron apoptotic process;GO:0002250//adaptive immune response;GO:2001180//negative regulation of interleukin-10 secretion;GO:0031642//negative regulation of myelination;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0001783//B cell apoptotic process;GO:0050852//T cell receptor signaling pathway;GO:0042552//myelination;GO:0042130//negative regulation of T cell proliferation;GO:2000666//negative regulation of interleukin-13 secretion;GO:0048713//regulation of oligodendrocyte differentiation;GO:0006959//humoral immune response;GO:0006915//apoptotic process;GO:0071356//cellular response to tumor necrosis factor;GO:0097252//oligodendrocyte apoptotic process;GO:0030889//negative regulation of B cell proliferation;GO:2000663//negative regulation of interleukin-5 secretion,GO:0005515//protein binding,K05157//Cytokine-cytokine receptor interaction
27243,0,32,1,6,67,0,0,0,0,0,0,0,CHMP2A;charged multivesicular body protein 2A,GO:0031902//late endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0019058//viral life cycle;GO:0050792//regulation of viral process;GO:0016032//viral process;GO:1902188//positive regulation of viral release from host cell;GO:0061024//membrane organization;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0045184//establishment of protein localization,GO:0019904//protein domain specific binding;GO:0005515//protein binding,K12191//Endocytosis
27244,0,0,0,27,49,50,0,1,39,0,21,0,SESN1;sestrin 1,GO:0005634//nucleus,GO:0006974//cellular response to DNA damage stimulus;GO:1901031//regulation of response to reactive oxygen species;GO:0051896//regulation of protein kinase B signaling;GO:0008285//negative regulation of cell proliferation;GO:0007050//cell cycle arrest,-,K10141//p53 signaling pathway
27245,113,5,0,0,0,0,15,55,75,0,31,0,"AHDC1;AT hook, DNA binding motif, containing 1",-,-,GO:0003677//DNA binding,K02350//Fanconi anemia pathway;Metabolic pathways
27246,0,0,0,0,57,17,51,0,44,0,5,0,RNF115;ring finger protein 115,GO:0005829//cytosol,GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0051865//protein autoubiquitination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination,GO:0008270//zinc ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
27247,0,0,0,0,15,0,0,0,15,0,0,0,NFU1;NFU1 iron-sulfur cluster scaffold,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus,GO:0016226//iron-sulfur cluster assembly,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005506//iron ion binding;GO:0005515//protein binding",K04382//mRNA surveillance pathway;Cell cycle - yeast;Oocyte meiosis;Wnt signaling pathway;Hepatitis C;TGF-beta signaling pathway;Meiosis - yeast;Long-term depression;Chagas disease (American trypanosomiasis);Dopaminergic synapse;Tight junction
27248,0,187,32,111,384,33,3,0,19,0,120,0,ERLEC1;endoplasmic reticulum lectin 1,GO:0005788//endoplasmic reticulum lumen,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0001948//glycoprotein binding;GO:0005515//protein binding,K14008//Protein processing in endoplasmic reticulum
27249,0,42,1,33,79,0,0,0,0,0,0,0,"MMADHC;methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria",GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006766//vitamin metabolic process;GO:0009235//cobalamin metabolic process,-,-
27250,0,74,2,182,563,12,16,0,24,0,20,0,PDCD4;programmed cell death 4 (neoplastic transformation inhibitor),GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007569//cell aging;GO:0043508//negative regulation of JUN kinase activity",GO:0005515//protein binding;GO:0003723//RNA binding,K03260//Viral myocarditis;RNA transport;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
27252,93,0,0,11,14,42,0,0,8,0,0,0,KLHL20;kelch-like family member 20,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0030424//axon;GO:0016605//PML body;GO:0048471//perinuclear region of cytoplasm,GO:0035455//response to interferon-alpha;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0006895//Golgi to endosome transport;GO:0007010//cytoskeleton organization;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0003779//actin binding;GO:0019964//interferon-gamma binding,-
27253,0,0,0,0,0,20,19,2,63,0,12,0,PCDH17;protocadherin 17,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
27254,0,0,0,0,0,14,0,0,12,0,4,0,"CSDC2;cold shock domain containing C2, RNA binding",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0006355//regulation of transcription, DNA-templated",GO:0003723//RNA binding;GO:0003677//DNA binding,-
27255,78,0,0,0,0,24,0,0,2,0,0,0,CNTN6;contactin 6,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0007411//axon guidance;GO:0007417//central nervous system development;GO:0007155//cell adhesion;GO:0007219//Notch signaling pathway,-,-
27257,6,0,0,30,36,19,0,0,0,0,12,0,"LSM1;LSM1, U6 small nuclear RNA associated",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex,"GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000375//RNA splicing, via transesterification reactions;GO:0006397//mRNA processing;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0071044//histone mRNA catabolic process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12620//RNA degradation
27258,0,0,0,47,34,0,0,0,0,0,0,0,"LSM3;LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12622//RNA degradation;Spliceosome
27283,0,0,0,0,0,0,0,0,14,0,0,0,TINAG;tubulointerstitial nephritis antigen,GO:0005604//basement membrane,GO:0006955//immune response;GO:0006898//receptor-mediated endocytosis;GO:0006508//proteolysis;GO:0007155//cell adhesion,GO:0000166//nucleotide binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0030247//polysaccharide binding,K01363//Antigen processing and presentation;Lysosome
27284,0,0,0,0,0,0,0,0,49,0,0,0,"SULT1B1;sulfotransferase family, cytosolic, 1B, member 1",GO:0005829//cytosol,GO:0018958//phenol-containing compound metabolic process;GO:0030855//epithelial cell differentiation;GO:0051923//sulfation;GO:0008202//steroid metabolic process;GO:0042403//thyroid hormone metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006576//cellular biogenic amine metabolic process;GO:0009812//flavonoid metabolic process,GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity,-
27285,0,1,41,0,0,0,0,0,2,0,12,0,TEKT2;tektin 2 (testicular),GO:0031514//motile cilium;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0036159//inner dynein arm assembly;GO:0030030//cell projection organization;GO:0030317//sperm motility,-,K04688//TGF-beta signaling pathway;ErbB signaling pathway;Fc gamma R-mediated phagocytosis;Acute myeloid leukemia;mTOR signaling pathway;Insulin signaling pathway
27286,0,29,0,0,19,19,0,0,44,0,6,0,"SRPX2;sushi-repeat containing protein, X-linked 2",GO:0097060//synaptic membrane;GO:0005737//cytoplasm;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0009986//cell surface;GO:0005615//extracellular space,GO:0001525//angiogenesis;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0051965//positive regulation of synapse assembly;GO:0071625//vocalization behavior;GO:0048870//cell motility;GO:0042325//regulation of phosphorylation,GO:0005102//receptor binding;GO:0036458//hepatocyte growth factor binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K14407//mRNA surveillance pathway;K06496//Malaria;Cell adhesion molecules (CAMs);Staphylococcus aureus infection
27287,0,0,32,0,0,0,3,0,0,0,2,0,VENTX;VENT homeobox,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
27288,0,0,0,0,0,0,35,0,22,0,0,0,"RBMXL2;RNA binding motif protein, X-linked-like 2",GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K12885//Spliceosome
27289,0,0,0,0,0,0,0,0,24,0,0,0,RND1;Rho family GTPase 1,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005912//adherens junction;GO:0005856//cytoskeleton,GO:0007411//axon guidance;GO:0016322//neuron remodeling;GO:0007015//actin filament organization;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0007162//negative regulation of cell adhesion,GO:0003924//GTPase activity;GO:0005102//receptor binding;GO:0005525//GTP binding;GO:0005515//protein binding,K07531//Axon guidance
2729,0,18,53,9,77,0,0,0,50,0,35,0,"GCLC;glutamate-cysteine ligase, catalytic subunit",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0017109//glutamate-cysteine ligase complex,"GO:0051900//regulation of mitochondrial depolarization;GO:0006805//xenobiotic metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0044281//small molecule metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0019852//L-ascorbic acid metabolic process;GO:0006750//glutathione biosynthetic process;GO:0009408//response to heat;GO:0046685//response to arsenic-containing substance;GO:0043066//negative regulation of apoptotic process;GO:0051409//response to nitrosative stress;GO:0006536//glutamate metabolic process;GO:0006534//cysteine metabolic process;GO:0008637//apoptotic mitochondrial changes;GO:0043524//negative regulation of neuron apoptotic process;GO:0009725//response to hormone;GO:0050880//regulation of blood vessel size;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000096//sulfur amino acid metabolic process;GO:0006979//response to oxidative stress;GO:0031397//negative regulation of protein ubiquitination;GO:0045454//cell redox homeostasis;GO:0034641//cellular nitrogen compound metabolic process",GO:0043531//ADP binding;GO:0000287//magnesium ion binding;GO:0050662//coenzyme binding;GO:0005524//ATP binding;GO:0046982//protein heterodimerization activity;GO:0016595//glutamate binding;GO:0004357//glutamate-cysteine ligase activity,K11204//Metabolic pathways;Glutathione metabolism
27291,0,0,0,30,14,21,0,0,16,0,1,0,R3HCC1L;R3H domain and coiled-coil containing 1-like,GO:0035145//exon-exon junction complex,-,GO:0000166//nucleotide binding,-
27292,34,29,5,69,63,0,16,0,13,106,63,0,DIMT1;DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0031167//rRNA methylation,"GO:0052909//18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity;GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0044822//poly(A) RNA binding",-
27293,0,0,0,0,0,0,0,0,10,0,0,0,"SMPDL3B;sphingomyelin phosphodiesterase, acid-like 3B",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0006685//sphingomyelin catabolic process,"GO:0004767//sphingomyelin phosphodiesterase activity;GO:0016798//hydrolase activity, acting on glycosyl bonds",-
27294,0,0,0,0,0,0,20,0,25,0,0,0,DHDH;dihydrodiol dehydrogenase (dimeric),-,GO:0005975//carbohydrate metabolic process;GO:0055114//oxidation-reduction process;GO:0042843//D-xylose catabolic process,"GO:0009055//electron carrier activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0008746//NAD(P)+ transhydrogenase activity;GO:0047837//D-xylose 1-dehydrogenase (NADP+) activity",K00078//Pentose and glucuronate interconversions;Metabolism of xenobiotics by cytochrome P450
27295,0,0,0,0,0,0,37,0,11,0,11,0,PDLIM3;PDZ and LIM domain 3,GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0030018//Z disc,GO:0007507//heart development;GO:0007015//actin filament organization,GO:0008092//cytoskeletal protein binding;GO:0008307//structural constituent of muscle;GO:0005515//protein binding;GO:0008270//zinc ion binding,K07520//Axon guidance;K05760//Leukocyte transendothelial migration;Focal adhesion;VEGF signaling pathway;Chemokine signaling pathway;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton
27296,0,0,0,43,27,0,0,0,12,0,20,0,TP53TG5;TP53 target 5,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030308//negative regulation of cell growth;GO:0035556//intracellular signal transduction,-,-
27297,0,11,0,11,40,21,0,0,0,0,0,0,CRCP;CGRP receptor component,GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0009360//DNA polymerase III complex;GO:0001669//acrosomal vesicle,GO:0007218//neuropeptide signaling pathway;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter,GO:0000166//nucleotide binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0001635//calcitonin gene-related peptide receptor activity,K11447//Transcriptional misregulation in cancer
27299,0,0,0,0,0,12,31,0,31,0,0,0,"ADAMDEC1;ADAM-like, decysin 1",GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0006955//immune response;GO:0007162//negative regulation of cell adhesion,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
273,0,0,0,11,0,8,6,60,95,37,0,0,AMPH;amphiphysin,GO:0015629//actin cytoskeleton;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0031256//leading edge membrane,GO:0007268//synaptic transmission;GO:0048488//synaptic vesicle endocytosis;GO:0007612//learning;GO:0006897//endocytosis,GO:0005543//phospholipid binding;GO:0005515//protein binding,K12562//Fc gamma R-mediated phagocytosis
2730,0,2,1,36,46,9,27,3,71,0,21,0,"GCLM;glutamate-cysteine ligase, modifier subunit",GO:0005829//cytosol;GO:0017109//glutamate-cysteine ligase complex,GO:0043524//negative regulation of neuron apoptotic process;GO:0008637//apoptotic mitochondrial changes;GO:0034641//cellular nitrogen compound metabolic process;GO:0006979//response to oxidative stress;GO:0000096//sulfur amino acid metabolic process;GO:0050880//regulation of blood vessel size;GO:0006750//glutathione biosynthetic process;GO:1901687//glutathione derivative biosynthetic process;GO:0044281//small molecule metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0035229//positive regulation of glutamate-cysteine ligase activity;GO:0042493//response to drug;GO:0051900//regulation of mitochondrial depolarization;GO:0051409//response to nitrosative stress;GO:0006534//cysteine metabolic process;GO:0006536//glutamate metabolic process,GO:0035226//glutamate-cysteine ligase catalytic subunit binding;GO:0046982//protein heterodimerization activity;GO:0004357//glutamate-cysteine ligase activity,K11205//Metabolic pathways;Glutathione metabolism
27300,0,19,0,14,68,0,0,0,11,0,0,0,ZNF544;zinc finger protein 544,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
27301,0,0,0,0,0,0,0,0,42,0,0,0,APEX2;APEX nuclease (apurinic/apyrimidinic endonuclease) 2,GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006284//base-excision repair;GO:0007049//cell cycle;GO:0006310//DNA recombination",GO:0008311//double-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity,K10772//Base excision repair
27302,0,0,0,0,0,0,0,0,3,0,0,0,BMP10;bone morphogenetic protein 10,GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0060038//cardiac muscle cell proliferation;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0055015//ventricular cardiac muscle cell development;GO:0060298//positive regulation of sarcomere organization;GO:0007512//adult heart development;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0045214//sarcomere organization;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis;GO:0007155//cell adhesion;GO:0010596//negative regulation of endothelial cell migration;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030198//extracellular matrix organization;GO:0055117//regulation of cardiac muscle contraction;GO:0032924//activin receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0060347//heart trabecula formation;GO:0030336//negative regulation of cell migration;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0030308//negative regulation of cell growth;GO:0030509//BMP signaling pathway",GO:0008083//growth factor activity;GO:0033612//receptor serine/threonine kinase binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005179//hormone activity,-
27303,33,0,0,1,0,39,31,0,69,0,0,0,"RBMS3;RNA binding motif, single stranded interacting protein 3",GO:0005737//cytoplasm,GO:0045727//positive regulation of translation,GO:0003730//mRNA 3'-UTR binding;GO:0000166//nucleotide binding,-
27304,0,0,0,0,1,0,0,0,9,0,0,189,MOCS3;molybdenum cofactor synthesis 3,GO:0005829//cytosol,GO:0002098//tRNA wobble uridine modification;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0002143//tRNA wobble position uridine thiolation;GO:0032447//protein urmylation;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0006766//vitamin metabolic process;GO:0018192//enzyme active site formation via L-cysteine persulfide;GO:0034227//tRNA thio-modification;GO:0018117//protein adenylylation,GO:0070733//protein adenylyltransferase activity;GO:0016783//sulfurtransferase activity;GO:0004792//thiosulfate sulfurtransferase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity;GO:0042292//URM1 activating enzyme activity;GO:0061604//molybdopterin-synthase sulfurtransferase activity;GO:0061605//molybdopterin-synthase adenylyltransferase activity,K11996//Sulfur relay system
27306,0,0,0,0,0,0,0,0,27,0,0,0,HPGDS;hematopoietic prostaglandin D synthase,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0007626//locomotory behavior;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0019371//cyclooxygenase pathway;GO:0006805//xenobiotic metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0006693//prostaglandin metabolic process;GO:0019369//arachidonic acid metabolic process,GO:0004667//prostaglandin-D synthase activity;GO:0004364//glutathione transferase activity;GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity,K01830//Arachidonic acid metabolism;Metabolic pathways
27309,0,61,1,15,13,0,38,0,26,0,0,0,ZNF330;zinc finger protein 330,"GO:0005730//nucleolus;GO:0030496//midbody;GO:0000775//chromosome, centromeric region",-,GO:0046872//metal ion binding;GO:0008270//zinc ion binding,-
2731,59,0,0,0,0,0,43,0,67,0,0,0,GLDC;glycine dehydrogenase (decarboxylating),GO:0005739//mitochondrion,GO:0006546//glycine catabolic process;GO:0055114//oxidation-reduction process,GO:0004375//glycine dehydrogenase (decarboxylating) activity;GO:0030170//pyridoxal phosphate binding;GO:0016829//lyase activity;GO:0009055//electron carrier activity,"K00281//Metabolic pathways;Glycine, serine and threonine metabolism"
27314,0,0,50,21,29,0,9,0,23,0,5,0,"RAB30;RAB30, member RAS oncogene family",GO:0031985//Golgi cisterna;GO:0005802//trans-Golgi network;GO:0005795//Golgi stack;GO:0005801//cis-Golgi network;GO:0016020//membrane,GO:0015031//protein transport;GO:0007030//Golgi organization;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
27315,72,0,1,0,14,0,0,0,11,0,0,0,PGAP2;post-GPI attachment to proteins 2,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:0015031//protein transport;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042770//signal transduction in response to DNA damage;GO:0006506//GPI anchor biosynthetic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,GO:0008565//protein transporter activity,-
27316,0,104,0,41,88,4,0,0,17,0,0,0,"RBMX;RNA binding motif protein, X-linked",GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005719//nuclear euchromatin;GO:0044530//supraspliceosomal complex;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0071013//catalytic step 2 spliceosome;GO:0070062//extracellular vesicular exosome,"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0071347//cellular response to interleukin-1;GO:0000398//mRNA splicing, via spliceosome;GO:0006509//membrane protein ectodomain proteolysis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051260//protein homooligomerization;GO:0001649//osteoblast differentiation",GO:0003723//RNA binding;GO:0001047//core promoter binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding,K12885//Spliceosome
27319,0,0,0,0,0,17,0,0,15,0,0,0,"BHLHE22;basic helix-loop-helix family, member e22",GO:0005634//nucleus,"GO:0060040//retinal bipolar neuron differentiation;GO:0021960//anterior commissure morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0021957//corticospinal tract morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021796//cerebral cortex regionalization;GO:0006366//transcription from RNA polymerase II promoter;GO:0021540//corpus callosum morphogenesis",GO:0042803//protein homodimerization activity;GO:0003682//chromatin binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
27324,0,0,0,0,0,37,0,0,12,0,0,0,TOX3;TOX high mobility group box family member 3,GO:0005634//nucleus,"GO:0043524//negative regulation of neuron apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0034056//estrogen response element binding;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding,-
27327,71,4,1,1,34,0,49,0,76,3,2,0,TNRC6A;trinucleotide repeat containing 6A,GO:0000932//cytoplasmic mRNA processing body;GO:0035068//micro-ribonucleoprotein complex;GO:0005829//cytosol,GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0010467//gene expression;GO:0007219//Notch signaling pathway;GO:0009267//cellular response to starvation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K15044//Influenza A
27328,0,0,0,0,8,19,10,35,39,0,16,0,PCDH11X;protocadherin 11 X-linked,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0010923//negative regulation of phosphatase activity;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
27329,0,0,0,0,0,0,29,0,0,0,0,0,ANGPTL3;angiopoietin-like 3,GO:0009986//cell surface;GO:0005615//extracellular space,GO:0006631//fatty acid metabolic process;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0030335//positive regulation of cell migration;GO:0008203//cholesterol metabolic process;GO:0009395//phospholipid catabolic process;GO:0006071//glycerol metabolic process;GO:0055088//lipid homeostasis;GO:0050996//positive regulation of lipid catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0042632//cholesterol homeostasis;GO:0007160//cell-matrix adhesion;GO:0019915//lipid storage;GO:0006644//phospholipid metabolic process;GO:0048844//artery morphogenesis;GO:0010519//negative regulation of phospholipase activity;GO:0070328//triglyceride homeostasis;GO:0055091//phospholipid homeostasis;GO:0009725//response to hormone;GO:0007229//integrin-mediated signaling pathway;GO:0007165//signal transduction,GO:0008083//growth factor activity;GO:0005178//integrin binding;GO:0004857//enzyme inhibitor activity;GO:0004859//phospholipase inhibitor activity,K08767//PPAR signaling pathway
2733,0,57,30,7,52,0,0,0,17,0,8,0,GLE1;GLE1 RNA export mediator,GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005643//nuclear pore;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0006406//mRNA export from nucleus,GO:0005515//protein binding;GO:0042802//identical protein binding,K06114//Tight junction
27330,0,30,1,13,31,22,1,0,48,0,22,0,"RPS6KA6;ribosomal protein S6 kinase, 90kDa, polypeptide 6",GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:2000381//negative regulation of mesoderm development;GO:0007268//synaptic transmission;GO:0007417//central nervous system development;GO:0006468//protein phosphorylation;GO:0007411//axon guidance;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0007165//signal transduction;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0045992//negative regulation of embryonic development",GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K04373//Long-term potentiation;Progesterone-mediated oocyte maturation;Oocyte meiosis;Neurotrophin signaling pathway;mTOR signaling pathway;MAPK signaling pathway
27332,0,0,1,68,167,34,1,0,56,0,0,0,ZNF638;zinc finger protein 638,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0008380//RNA splicing;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding,-
27333,35,0,0,0,0,10,62,1,6,336,0,0,GOLIM4;golgi integral membrane protein 4,GO:0005634//nucleus;GO:0032580//Golgi cisterna membrane;GO:0030139//endocytic vesicle;GO:0005796//Golgi lumen;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005801//cis-Golgi network;GO:0010008//endosome membrane;GO:0005794//Golgi apparatus,GO:0006810//transport,-,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton
27335,0,0,0,1,17,0,0,0,0,0,0,0,"EIF3K;eukaryotic translation initiation factor 3, subunit K",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016282//eukaryotic 43S preinitiation complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0016020//membrane;GO:0005852//eukaryotic translation initiation factor 3 complex,GO:0006413//translational initiation;GO:0006412//translation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0003743//translation initiation factor activity,-
27336,0,75,1,21,106,0,0,0,11,75,0,0,HTATSF1;HIV-1 Tat specific factor 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019079//viral genome replication;GO:0006351//transcription, DNA-templated;GO:0032784//regulation of DNA-templated transcription, elongation",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
27338,0,0,0,0,13,0,0,77,0,0,12,0,UBE2S;ubiquitin-conjugating enzyme E2S,GO:0005680//anaphase-promoting complex,GO:0070534//protein K63-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0010458//exit from mitosis;GO:0051488//activation of anaphase-promoting complex activity;GO:0010994//free ubiquitin chain polymerization;GO:0006464//cellular protein modification process;GO:0035519//protein K29-linked ubiquitination;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K10583//Ubiquitin mediated proteolysis
27339,0,77,2,19,55,21,0,1,26,135,0,429,PRPF19;pre-mRNA processing factor 19,GO:0005737//cytoplasm;GO:0005819//spindle;GO:0000974//Prp19 complex;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016607//nuclear speck,"GO:0006281//DNA repair;GO:0000245//spliceosomal complex assembly;GO:0000209//protein polyubiquitination;GO:0000398//mRNA splicing, via spliceosome",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0003677//DNA binding;GO:0034450//ubiquitin-ubiquitin ligase activity,K10599//Spliceosome;Ubiquitin mediated proteolysis
2734,369,32,0,15,12,0,1,2,53,0,0,331,GLG1;golgi glycoprotein 1,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0031012//extracellular matrix,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0007596//blood coagulation;GO:0010955//negative regulation of protein processing;GO:0060349//bone morphogenesis;GO:0032330//regulation of chondrocyte differentiation;GO:0050900//leukocyte migration,GO:0005102//receptor binding,K06816//Cell adhesion molecules (CAMs)
27340,1,0,55,13,11,36,18,0,76,0,25,0,"UTP20;UTP20, small subunit (SSU) processome component, homolog (yeast)","GO:0032040//small-subunit processome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030686//90S preribosome;GO:0005730//nucleolus;GO:0030688//preribosome, small subunit precursor","GO:0008285//negative regulation of cell proliferation;GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
27341,0,36,1,49,27,0,12,0,30,0,112,0,RRP7A;ribosomal RNA processing 7 homolog A (S. cerevisiae),-,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K14545//Ribosome biogenesis in eukaryotes
27342,91,1008,540,800,1265,0,60,1425,365,281,1969,3,RABGEF1;RAB guanine nucleotide exchange factor (GEF) 1,GO:0005769//early endosome;GO:0055037//recycling endosome,GO:0006897//endocytosis;GO:0032851//positive regulation of Rab GTPase activity;GO:0006612//protein targeting to membrane,GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
27343,41,0,0,1,0,0,9,0,24,0,0,0,"POLL;polymerase (DNA directed), lambda",GO:0005634//nucleus,GO:0071897//DNA biosynthetic process;GO:0006289//nucleotide-excision repair;GO:0006260//DNA replication;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006261//DNA-dependent DNA replication,GO:0003887//DNA-directed DNA polymerase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0016829//lyase activity,K03512//Base excision repair;Non-homologous end-joining
27344,0,0,0,0,0,0,0,0,5,0,0,0,PCSK1N;proprotein convertase subtilisin/kexin type 1 inhibitor,GO:0005802//trans-Golgi network;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0070062//extracellular vesicular exosome,GO:0016486//peptide hormone processing;GO:0009409//response to cold;GO:0010951//negative regulation of endopeptidase activity;GO:0007218//neuropeptide signaling pathway;GO:0002021//response to dietary excess,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0005102//receptor binding,-
27345,0,0,0,0,0,0,25,22,13,0,23,0,"KCNMB4;potassium large conductance calcium-activated channel, subfamily M, beta member 4",GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0001508//action potential;GO:0046928//regulation of neurotransmitter secretion;GO:0005513//detection of calcium ion;GO:0006813//potassium ion transport;GO:0007596//blood coagulation;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0019229//regulation of vasoconstriction,GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding,K04941//Vascular smooth muscle contraction
27346,0,89,0,271,288,10,0,0,20,0,108,0,TMEM97;transmembrane protein 97,GO:0005791//rough endoplasmic reticulum;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0031965//nuclear membrane,GO:0042632//cholesterol homeostasis;GO:0001558//regulation of cell growth,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
27347,183,47,1,29,107,0,0,72,9,0,4,0,STK39;serine threonine kinase 39,GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:2000681//negative regulation of rubidium ion transport;GO:0050727//regulation of inflammatory response;GO:0071476//cellular hypotonic response;GO:0043268//positive regulation of potassium ion transport;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006950//response to stress;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0018107//peptidyl-threonine phosphorylation;GO:2000687//negative regulation of rubidium ion transmembrane transporter activity;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0018105//peptidyl-serine phosphorylation;GO:0023014//signal transduction by phosphorylation,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0005524//ATP binding,-
27348,0,0,0,0,7,0,0,0,19,0,5,0,"TOR1B;torsin family 1, member B (torsin B)",GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0005788//endoplasmic reticulum lumen,GO:0051260//protein homooligomerization;GO:0007029//endoplasmic reticulum organization;GO:0006986//response to unfolded protein;GO:0071763//nuclear membrane organization;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
27349,0,28,0,4,0,0,81,0,6,0,0,0,MCAT;malonyl CoA:ACP acyltransferase (mitochondrial),GO:0005739//mitochondrion,GO:0008152//metabolic process;GO:0006633//fatty acid biosynthetic process,GO:0004314//[acyl-carrier-protein] S-malonyltransferase activity;GO:0016740//transferase activity;GO:0044822//poly(A) RNA binding,"K00645//Glycine, serine and threonine metabolism;Cyanoamino acid metabolism;Homologous recombination;Biosynthesis of secondary metabolites;Mismatch repair;Methane metabolism;Pyrimidine metabolism;One carbon pool by folate;Microbial metabolism in diverse environments;Purine metabolism;Fatty acid biosynthesis;Metabolic pathways;Glyoxylate and dicarboxylate metabolism;DNA replication"
2735,0,0,1,0,0,14,20,0,11,0,15,60,GLI1;GLI family zinc finger 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0072372//primary cilium;GO:0005730//nucleolus,"GO:0007283//spermatogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045740//positive regulation of DNA replication;GO:0030324//lung development;GO:0006366//transcription from RNA polymerase II promoter;GO:0009913//epidermal cell differentiation;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0060032//notochord regression;GO:0048546//digestive tract morphogenesis;GO:0007224//smoothened signaling pathway;GO:0008589//regulation of smoothened signaling pathway;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0007418//ventral midline development;GO:0009953//dorsal/ventral pattern formation;GO:0021696//cerebellar cortex morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0021983//pituitary gland development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0044212//transcription regulatory region DNA binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K06230//Pathways in cancer;Hedgehog signaling pathway;Basal cell carcinoma
27350,0,1,0,7,9,0,0,0,0,0,0,0,"APOBEC3C;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0080111//DNA demethylation;GO:0045071//negative regulation of viral genome replication;GO:0009972//cytidine deamination;GO:0010529//negative regulation of transposition;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response,"GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding",K01500//Microbial metabolism in diverse environments;Atrazine degradation
27351,0,0,1,0,0,0,2,0,12,0,0,0,DESI1;desumoylating isopeptidase 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0042802//identical protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
27352,0,3,0,1,20,0,0,58,0,0,0,0,SGSM3;small G protein signaling modulator 3,GO:0005921//gap junction;GO:0005829//cytosol,GO:0032486//Rap protein signal transduction;GO:1902017//regulation of cilium assembly;GO:0033126//positive regulation of GTP catabolic process;GO:0007050//cell cycle arrest;GO:0032851//positive regulation of Rab GTPase activity;GO:0045732//positive regulation of protein catabolic process;GO:0048227//plasma membrane to endosome transport,GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding;GO:0005515//protein binding,K11247//Endocytosis
2736,89,0,0,0,0,0,45,0,63,0,14,0,GLI2;GLI family zinc finger 2,GO:0016607//nuclear speck;GO:0016020//membrane;GO:0005634//nucleus;GO:0031512//motile primary cilium;GO:0005737//cytoplasm,"GO:0045740//positive regulation of DNA replication;GO:0009612//response to mechanical stimulus;GO:0030324//lung development;GO:0009913//epidermal cell differentiation;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:0048566//embryonic digestive tract development;GO:0030879//mammary gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060603//mammary gland duct morphogenesis;GO:0021517//ventral spinal cord development;GO:0060322//head development;GO:0042733//embryonic digit morphogenesis;GO:0021508//floor plate formation;GO:0008589//regulation of smoothened signaling pathway;GO:0007411//axon guidance;GO:0007389//pattern specification process;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002062//chondrocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032331//negative regulation of chondrocyte differentiation;GO:0001701//in utero embryonic development;GO:0021983//pituitary gland development;GO:0006355//regulation of transcription, DNA-templated;GO:0001501//skeletal system development;GO:0002076//osteoblast development;GO:0021513//spinal cord dorsal/ventral patterning;GO:0009954//proximal/distal pattern formation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001649//osteoblast differentiation;GO:0030902//hindbrain development;GO:0060032//notochord regression;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0007224//smoothened signaling pathway;GO:0090103//cochlea morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0060513//prostatic bud formation;GO:0048589//developmental growth;GO:0021965//spinal cord ventral commissure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0021696//cerebellar cortex morphogenesis;GO:0008283//cell proliferation;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0007442//hindgut morphogenesis;GO:0035295//tube development;GO:0071407//cellular response to organic cyclic compound;GO:0007418//ventral midline development;GO:0048666//neuron development;GO:0007507//heart development;GO:0001822//kidney development",GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding,K06230//Basal cell carcinoma;Pathways in cancer;Hedgehog signaling pathway
2737,0,0,0,0,0,0,0,0,62,0,0,0,GLI3;GLI family zinc finger 3,GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005929//cilium;GO:0005829//cytosol;GO:0072372//primary cilium;GO:0016592//mediator complex;GO:0005737//cytoplasm;GO:0017053//transcriptional repressor complex,"GO:0042060//wound healing;GO:0060594//mammary gland specification;GO:0042733//embryonic digit morphogenesis;GO:0021801//cerebral cortex radial glia guided migration;GO:0045665//negative regulation of neuron differentiation;GO:0070242//thymocyte apoptotic process;GO:0060873//anterior semicircular canal development;GO:0007411//axon guidance;GO:0060367//sagittal suture morphogenesis;GO:0048593//camera-type eye morphogenesis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0043585//nose morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045060//negative thymic T cell selection;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0001656//metanephros development;GO:0045669//positive regulation of osteoblast differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0043586//tongue development;GO:0030324//lung development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043627//response to estrogen;GO:0048566//embryonic digestive tract development;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021631//optic nerve morphogenesis;GO:0016485//protein processing;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060364//frontal suture morphogenesis;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0046639//negative regulation of alpha-beta T cell differentiation;GO:0006351//transcription, DNA-templated;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007442//hindgut morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0060021//palate development;GO:0002052//positive regulation of neuroblast proliferation;GO:0022018//lateral ganglionic eminence cell proliferation;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0021766//hippocampus development;GO:0060366//lambdoid suture morphogenesis;GO:0007507//heart development;GO:0035108//limb morphogenesis;GO:0060840//artery development;GO:0048704//embryonic skeletal system morphogenesis;GO:0033077//T cell differentiation in thymus;GO:0009952//anterior/posterior pattern specification;GO:0042307//positive regulation of protein import into nucleus;GO:0048709//oligodendrocyte differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009954//proximal/distal pattern formation;GO:0007224//smoothened signaling pathway;GO:0021861//forebrain radial glial cell differentiation;GO:0061005//cell differentiation involved in kidney development;GO:0060875//lateral semicircular canal development;GO:0048589//developmental growth;GO:0030318//melanocyte differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0035035//histone acetyltransferase binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0042826//histone deacetylase binding,K06230//Hedgehog signaling pathway;Pathways in cancer;Basal cell carcinoma
2738,0,0,0,0,0,0,0,0,26,0,0,0,GLI4;GLI family zinc finger 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2739,0,103,2,226,1343,0,1,1,14,0,0,0,GLO1;glyoxalase I,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0009438//methylglyoxal metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0005975//carbohydrate metabolic process;GO:0030316//osteoclast differentiation;GO:0006749//glutathione metabolic process,GO:0008270//zinc ion binding;GO:0004462//lactoylglutathione lyase activity,K01759//Pyruvate metabolism;MAPK signaling pathway - yeast
274,0,1,0,4,16,14,19,37,27,0,17,630,BIN1;bridging integrator 1,GO:0033268//node of Ranvier;GO:0043679//axon terminus;GO:0043196//varicosity;GO:0005737//cytoplasm;GO:0044300//cerebellar mossy fiber;GO:0030018//Z disc;GO:0030315//T-tubule;GO:0060987//lipid tube;GO:0008021//synaptic vesicle;GO:0005634//nucleus;GO:0031674//I band;GO:0043194//axon initial segment;GO:0030424//axon;GO:0015629//actin cytoskeleton,GO:0045664//regulation of neuron differentiation;GO:0016032//viral process;GO:0043547//positive regulation of GTPase activity;GO:0042692//muscle cell differentiation;GO:0006897//endocytosis;GO:0008283//cell proliferation;GO:0048711//positive regulation of astrocyte differentiation;GO:0060988//lipid tube assembly;GO:0043065//positive regulation of apoptotic process;GO:0045807//positive regulation of endocytosis;GO:0071156//regulation of cell cycle arrest,GO:0032403//protein complex binding;GO:0048156//tau protein binding;GO:0051020//GTPase binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding,K12562//Fc gamma R-mediated phagocytosis
2740,1,0,0,0,23,1,0,34,0,0,18,0,GLP1R;glucagon-like peptide 1 receptor,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006950//response to stress;GO:0019933//cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007190//activation of adenylate cyclase activity;GO:0008016//regulation of heart contraction;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0007611//learning or memory;GO:0044281//small molecule metabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0004967//glucagon receptor activity;GO:0004888//transmembrane signaling receptor activity,K04581//Neuroactive ligand-receptor interaction
2741,0,0,0,0,0,0,17,0,79,0,9,0,"GLRA1;glycine receptor, alpha 1",GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0060077//inhibitory synapse;GO:0043231//intracellular membrane-bounded organelle;GO:0034707//chloride channel complex;GO:0005887//integral component of plasma membrane,"GO:0006936//muscle contraction;GO:0034220//ion transmembrane transport;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0060012//synaptic transmission, glycinergic;GO:0001964//startle response;GO:0007601//visual perception;GO:0051970//negative regulation of transmission of nerve impulse;GO:1902476//chloride transmembrane transport;GO:0007628//adult walking behavior;GO:0055085//transmembrane transport;GO:0042391//regulation of membrane potential;GO:0007340//acrosome reaction;GO:0006811//ion transport;GO:0007218//neuropeptide signaling pathway;GO:2000344//positive regulation of acrosome reaction;GO:0060013//righting reflex;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0050884//neuromuscular process controlling posture;GO:0006821//chloride transport;GO:0001508//action potential",GO:0016594//glycine binding;GO:0030977//taurine binding;GO:0022824//transmitter-gated ion channel activity;GO:0016934//extracellular-glycine-gated chloride channel activity;GO:0005515//protein binding,K05193//Neuroactive ligand-receptor interaction
2742,0,0,0,0,0,0,29,0,11,0,0,0,"GLRA2;glycine receptor, alpha 2",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0007218//neuropeptide signaling pathway;GO:1902476//chloride transmembrane transport;GO:0007416//synapse assembly,GO:0016594//glycine binding;GO:0016934//extracellular-glycine-gated chloride channel activity;GO:0022824//transmitter-gated ion channel activity,K05194//Neuroactive ligand-receptor interaction
27429,0,20,0,6,27,0,0,171,57,0,9,0,HTRA2;HtrA serine peptidase 2,GO:0005829//cytosol;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0016020//membrane;GO:0005758//mitochondrial intermembrane space;GO:0005856//cytoskeleton,GO:0034605//cellular response to heat;GO:0035458//cellular response to interferon-beta;GO:0097194//execution phase of apoptosis;GO:0048666//neuron development;GO:0006672//ceramide metabolic process;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0044257//cellular protein catabolic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0019742//pentacyclic triterpenoid metabolic process;GO:0010942//positive regulation of cell death;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030900//forebrain development;GO:0007628//adult walking behavior;GO:0040014//regulation of multicellular organism growth;GO:0045786//negative regulation of cell cycle;GO:0034599//cellular response to oxidative stress;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0007005//mitochondrion organization;GO:0071300//cellular response to retinoic acid;GO:0009635//response to herbicide;GO:0071363//cellular response to growth factor stimulus;GO:0006508//proteolysis;GO:0016540//protein autoprocessing;GO:0060548//negative regulation of cell death;GO:0043065//positive regulation of apoptotic process,GO:0051082//unfolded protein binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity;GO:0008233//peptidase activity,K08669//Parkinson's disease
2743,0,0,0,0,0,13,0,0,20,0,2,0,"GLRB;glycine receptor, beta",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,"GO:0060013//righting reflex;GO:0007218//neuropeptide signaling pathway;GO:0034220//ion transmembrane transport;GO:0006811//ion transport;GO:0042391//regulation of membrane potential;GO:0007340//acrosome reaction;GO:0055085//transmembrane transport;GO:0007628//adult walking behavior;GO:0051291//protein heterooligomerization;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:1902476//chloride transmembrane transport;GO:0060012//synaptic transmission, glycinergic;GO:0007601//visual perception;GO:0001964//startle response",GO:0016594//glycine binding;GO:0016934//extracellular-glycine-gated chloride channel activity;GO:0005515//protein binding,K05196//Neuroactive ligand-receptor interaction
27430,0,11,0,7,23,0,52,0,43,113,6,0,"MAT2B;methionine adenosyltransferase II, beta",GO:0048269//methionine adenosyltransferase complex;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0032259//methylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0050790//regulation of catalytic activity;GO:0006730//one-carbon metabolic process;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0006556//S-adenosylmethionine biosynthetic process;GO:0055114//oxidation-reduction process,GO:0019899//enzyme binding;GO:0008831//dTDP-4-dehydrorhamnose reductase activity;GO:0048270//methionine adenosyltransferase regulator activity,K00789//Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
27433,0,0,0,0,0,0,0,0,45,0,0,0,"TOR2A;torsin family 2, member A",GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0051260//protein homooligomerization;GO:0051085//chaperone mediated protein folding requiring cofactor,GO:0005524//ATP binding;GO:0005179//hormone activity,-
27434,0,1,0,1,0,0,0,0,15,0,3,0,"POLM;polymerase (DNA directed), mu",GO:0005634//nucleus,GO:0071897//DNA biosynthetic process;GO:0006281//DNA repair;GO:0006261//DNA-dependent DNA replication;GO:0006310//DNA recombination,GO:0003887//DNA-directed DNA polymerase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K03513//Non-homologous end-joining
27436,0,24,0,43,137,1,35,0,92,0,24,193,EML4;echinoderm microtubule associated protein like 4,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0072686//mitotic spindle,GO:0007067//mitotic nuclear division;GO:0007017//microtubule-based process;GO:0007026//negative regulation of microtubule depolymerization,-,-
27439,188,0,0,23,50,23,22,1,64,0,20,0,"CECR6;cat eye syndrome chromosome region, candidate 6",-,-,-,-
2744,0,13,0,25,53,8,24,0,23,0,0,0,GLS;glutaminase,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0006537//glutamate biosynthetic process;GO:0051289//protein homotetramerization;GO:0006543//glutamine catabolic process;GO:0044281//small molecule metabolic process;GO:0001967//suckling behavior;GO:0008652//cellular amino acid biosynthetic process;GO:0014047//glutamate secretion;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0034641//cellular nitrogen compound metabolic process,GO:0005515//protein binding;GO:0004359//glutaminase activity,"K01425//Microbial metabolism in diverse environments;GABAergic synapse;Pyrimidine metabolism;D-Glutamine and D-glutamate metabolism;Metabolic pathways;Oxidative phosphorylation;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Proximal tubule bicarbonate reclamation;Nitrogen metabolism;Arginine and proline metabolism"
27440,0,1,0,4,8,0,0,1,0,0,22,0,"CECR5;cat eye syndrome chromosome region, candidate 5",GO:0005739//mitochondrion,-,-,-
27443,66,0,0,4,20,0,3,3,55,0,1,64,"CECR2;cat eye syndrome chromosome region, candidate 2",GO:0005634//nucleus;GO:0090537//CERF complex,GO:0000910//cytokinesis;GO:0097194//execution phase of apoptosis;GO:0016192//vesicle-mediated transport;GO:0021915//neural tube development;GO:0043044//ATP-dependent chromatin remodeling;GO:0007010//cytoskeleton organization;GO:0006309//apoptotic DNA fragmentation,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K06062//Notch signaling pathway;HTLV-I infection;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
27445,47,39,59,117,341,53,79,44,131,100,13,0,PCLO;piccolo presynaptic cytomatrix protein,GO:0005856//cytoskeleton;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0045202//synapse,GO:0017157//regulation of exocytosis;GO:0030073//insulin secretion;GO:0019933//cAMP-mediated signaling;GO:0007010//cytoskeleton organization;GO:0016079//synaptic vesicle exocytosis,GO:0005509//calcium ion binding;GO:0005522//profilin binding;GO:0005215//transporter activity;GO:0005544//calcium-dependent phospholipid binding,-
2745,0,0,0,0,27,0,0,0,5,0,0,0,GLRX;glutaredoxin (thioltransferase),GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0045838//positive regulation of membrane potential;GO:0044281//small molecule metabolic process;GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process;GO:0015949//nucleobase-containing small molecule interconversion;GO:2000651//positive regulation of sodium ion transmembrane transporter activity,GO:0009055//electron carrier activity;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0047485//protein N-terminus binding,K03676//Metabolic pathways;Pyrimidine metabolism;Purine metabolism
2746,0,268,140,198,585,14,40,338,55,0,136,1,GLUD1;glutamate dehydrogenase 1,GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0006538//glutamate catabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006541//glutamine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006537//glutamate biosynthetic process;GO:0032024//positive regulation of insulin secretion;GO:0072350//tricarboxylic acid metabolic process;GO:0044281//small molecule metabolic process,GO:0004353//glutamate dehydrogenase [NAD(P)+] activity;GO:0005515//protein binding;GO:0043531//ADP binding;GO:0042802//identical protein binding;GO:0070403//NAD+ binding;GO:0070728//leucine binding;GO:0005525//GTP binding;GO:0004352//glutamate dehydrogenase (NAD+) activity;GO:0005524//ATP binding,"K00261//Alanine, aspartate and glutamate metabolism;ABC transporters;Metabolic pathways;Arginine and proline metabolism;Nitrogen metabolism;D-Glutamine and D-glutamate metabolism;Proximal tubule bicarbonate reclamation"
2747,0,1,0,0,3,16,0,4,42,0,6,0,GLUD2;glutamate dehydrogenase 2,GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0006536//glutamate metabolic process;GO:0055114//oxidation-reduction process;GO:0006538//glutamate catabolic process;GO:0006537//glutamate biosynthetic process,GO:0004353//glutamate dehydrogenase [NAD(P)+] activity;GO:0004352//glutamate dehydrogenase (NAD+) activity;GO:0070728//leucine binding;GO:0043531//ADP binding;GO:0005525//GTP binding,"K00261//D-Glutamine and D-glutamate metabolism;Proximal tubule bicarbonate reclamation;Arginine and proline metabolism;Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;ABC transporters"
2749,3,0,0,0,0,0,57,0,18,0,0,0,GLUD1P3;glutamate dehydrogenase 1 pseudogene 3,-,-,-,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
275,44,20,0,5,0,0,1,0,1,0,27,0,AMT;aminomethyltransferase,GO:0005739//mitochondrion,GO:0032259//methylation;GO:0006546//glycine catabolic process,GO:0008483//transaminase activity;GO:0004047//aminomethyltransferase activity,"K00605//Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;One carbon pool by folate;Chloroalkane and chloroalkene degradation;Fatty acid metabolism;Ubiquinone and other terpenoid-quinone biosynthesis;Nitrogen metabolism;Naphthalene degradation;Metabolic pathways;Tyrosine metabolism"
2752,0,191,5,102,300,0,11,67,50,0,0,0,GLUL;glutamate-ammonia ligase,GO:0005634//nucleus;GO:0005791//rough endoplasmic reticulum;GO:0097386//glial cell projection;GO:0043204//perikaryon;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0043679//axon terminus;GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome,"GO:0050679//positive regulation of epithelial cell proliferation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0034641//cellular nitrogen compound metabolic process;GO:0007268//synaptic transmission;GO:0001504//neurotransmitter uptake;GO:0008283//cell proliferation;GO:0008652//cellular amino acid biosynthetic process;GO:0006538//glutamate catabolic process;GO:0006542//glutamine biosynthetic process;GO:0009267//cellular response to starvation;GO:0044281//small molecule metabolic process;GO:0051260//protein homooligomerization;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose",GO:0042802//identical protein binding;GO:0030145//manganese ion binding;GO:0016595//glutamate binding;GO:0045503//dynein light chain binding;GO:0004356//glutamate-ammonia ligase activity;GO:0004351//glutamate decarboxylase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,"K01915//Polyketide sugar unit biosynthesis;Arginine and proline metabolism;Nitrogen metabolism;Glutamatergic synapse;Two-component system;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;ABC transporters;Alanine, aspartate and glutamate metabolism;Biosynthesis of secondary metabolites;Folate biosynthesis;GABAergic synapse;Microbial metabolism in diverse environments;Streptomycin biosynthesis"
2760,0,0,2,0,0,10,0,34,17,0,0,0,GM2A;GM2 ganglioside activator,GO:0070062//extracellular vesicular exosome;GO:0009898//cytoplasmic side of plasma membrane;GO:0005739//mitochondrion;GO:0043202//lysosomal lumen;GO:0045179//apical cortex,GO:0007611//learning or memory;GO:0044281//small molecule metabolic process;GO:0019915//lipid storage;GO:0006869//lipid transport;GO:0050885//neuromuscular process controlling balance;GO:0006687//glycosphingolipid metabolic process;GO:0006689//ganglioside catabolic process;GO:0051345//positive regulation of hydrolase activity;GO:0009313//oligosaccharide catabolic process;GO:0006665//sphingolipid metabolic process,GO:0004563//beta-N-acetylhexosaminidase activity;GO:0005319//lipid transporter activity;GO:0016004//phospholipase activator activity,K12383//Lysosome
2762,0,30,1,40,21,21,0,0,49,0,0,0,"GMDS;GDP-mannose 4,6-dehydratase",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0007219//Notch signaling pathway;GO:0042351//'de novo' GDP-L-fucose biosynthetic process;GO:0019673//GDP-mannose metabolic process,"GO:0070401//NADP+ binding;GO:0008446//GDP-mannose 4,6-dehydratase activity",K01711//Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism
2764,0,99,1,37,133,0,0,0,18,0,6,0,"GMFB;glia maturation factor, beta",GO:0005622//intracellular,GO:0006469//negative regulation of protein kinase activity;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0007612//learning;GO:0007165//signal transduction;GO:0007626//locomotory behavior;GO:0043085//positive regulation of catalytic activity,GO:0004860//protein kinase inhibitor activity;GO:0004871//signal transducer activity;GO:0008083//growth factor activity;GO:0008047//enzyme activator activity;GO:0003779//actin binding,K05765//Axon guidance;Regulation of actin cytoskeleton;Pertussis;Fc gamma R-mediated phagocytosis
2765,67,0,0,0,0,0,0,0,0,0,1,0,GML;glycosylphosphatidylinositol anchored molecule like,GO:0005886//plasma membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane,"GO:0006915//apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0008285//negative regulation of cell proliferation",-,-
2766,0,42,1,38,99,26,0,1,18,0,0,0,GMPR;guanosine monophosphate reductase,GO:0005829//cytosol;GO:1902560//GMP reductase complex,GO:0044281//small molecule metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0009117//nucleotide metabolic process;GO:0043101//purine-containing compound salvage;GO:0055114//oxidation-reduction process;GO:0009409//response to cold,GO:0046872//metal ion binding;GO:0003920//GMP reductase activity,K00364//Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;One carbon pool by folate
2767,0,46,29,22,16,24,64,475,101,0,93,0,"GNA11;guanine nucleotide binding protein (G protein), alpha 11 (Gq class)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane,GO:0006184//GTP catabolic process;GO:0001501//skeletal system development;GO:0007596//blood coagulation;GO:0001508//action potential;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0045634//regulation of melanocyte differentiation;GO:0048066//developmental pigmentation;GO:0007165//signal transduction;GO:0071467//cellular response to pH;GO:0007507//heart development;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0031826//type 2A serotonin receptor binding,K04635//Amoebiasis;Vascular smooth muscle contraction;Calcium signaling pathway;Long-term depression;Cholinergic synapse;Chagas disease (American trypanosomiasis);Gap junction;GnRH signaling pathway
2768,0,30,1,8,70,0,24,0,13,0,10,0,GNA12;guanine nucleotide binding protein (G protein) alpha 12,GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex;GO:0031526//brush border membrane;GO:0005925//focal adhesion,GO:0007186//G-protein coupled receptor signaling pathway;GO:0032006//regulation of TOR signaling;GO:0008360//regulation of cell shape;GO:0042733//embryonic digit morphogenesis;GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0042493//response to drug;GO:0030154//cell differentiation;GO:0001701//in utero embryonic development;GO:0010762//regulation of fibroblast migration,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0031752//D5 dopamine receptor binding;GO:0004871//signal transducer activity,K04346//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Long-term depression;MAPK signaling pathway
2769,0,1,0,1,3,0,15,60,14,0,0,0,"GNA15;guanine nucleotide binding protein (G protein), alpha 15 (Gq class)",GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0007207//phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0030168//platelet activation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway,GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0001664//G-protein coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K04637//Amoebiasis;Calcium signaling pathway;Chagas disease (American trypanosomiasis)
2770,0,18,1,8,34,11,0,2,25,140,8,0,"GNAI1;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1",GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005834//heterotrimeric G-protein complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0030496//midbody,GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0043434//response to peptide hormone;GO:0051301//cell division;GO:0007049//cell cycle;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0031821//G-protein coupled serotonin receptor binding;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K04630//Toxoplasmosis;Melanogenesis;Gastric acid secretion;Long-term depression;Cholinergic synapse;GABAergic synapse;Chagas disease (American trypanosomiasis);Tight junction;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Morphine addiction;Glutamatergic synapse;Axon guidance;Cocaine addiction;Gap junction;Dopaminergic synapse;Chemokine signaling pathway;Progesterone-mediated oocyte maturation;Pertussis;Alcoholism;Serotonergic synapse
2771,0,0,0,3,46,1,27,0,0,201,0,6,"GNAI2;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2",GO:0005813//centrosome;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex;GO:0016020//membrane;GO:0045121//membrane raft;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030496//midbody;GO:0005829//cytosol,GO:0007584//response to nutrient;GO:0007596//blood coagulation;GO:0051924//regulation of calcium ion transport;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0001973//adenosine receptor signaling pathway;GO:0006184//GTP catabolic process;GO:0050805//negative regulation of synaptic transmission;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008284//positive regulation of cell proliferation;GO:0051301//cell division;GO:0007049//cell cycle;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0001664//G-protein coupled receptor binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004871//signal transducer activity,K04630//Chemokine signaling pathway;Axon guidance;Dopaminergic synapse;Gap junction;Cocaine addiction;Progesterone-mediated oocyte maturation;Serotonergic synapse;Alcoholism;Pertussis;Morphine addiction;Glutamatergic synapse;Cholinergic synapse;Long-term depression;Chagas disease (American trypanosomiasis);GABAergic synapse;Tight junction;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Toxoplasmosis;Melanogenesis;Gastric acid secretion
2773,0,1,0,43,64,0,49,90,22,0,1,0,"GNAI3;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3",GO:0005765//lysosomal membrane;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0016020//membrane;GO:0005834//heterotrimeric G-protein complex;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0042588//zymogen granule;GO:0030496//midbody,GO:0006184//GTP catabolic process;GO:0006810//transport;GO:0007596//blood coagulation;GO:0006906//vesicle fusion;GO:0007268//synaptic transmission;GO:0007194//negative regulation of adenylate cyclase activity;GO:0051301//cell division;GO:0007049//cell cycle;GO:0030168//platelet activation;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0019904//protein domain specific binding;GO:0004871//signal transducer activity;GO:0032794//GTPase activating protein binding;GO:0003924//GTPase activity;GO:0046872//metal ion binding,K04630//Chemokine signaling pathway;Gap junction;Axon guidance;Cocaine addiction;Dopaminergic synapse;Serotonergic synapse;Alcoholism;Pertussis;Progesterone-mediated oocyte maturation;Glutamatergic synapse;Morphine addiction;GABAergic synapse;Chagas disease (American trypanosomiasis);Tight junction;Cholinergic synapse;Long-term depression;Retrograde endocannabinoid signaling;Leukocyte transendothelial migration;Toxoplasmosis;Gastric acid secretion;Melanogenesis
2774,60,13,42,72,74,2,31,0,52,0,89,30,"GNAL;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex,GO:0007608//sensory perception of smell;GO:0006184//GTP catabolic process;GO:0007190//activation of adenylate cyclase activity;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0001975//response to amphetamine;GO:0031000//response to caffeine;GO:0007165//signal transduction;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0001664//G-protein coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity,K04633//Amoebiasis;Calcium signaling pathway;Olfactory transduction;Dopaminergic synapse;Chagas disease (American trypanosomiasis)
2775,11,0,0,0,12,17,46,0,72,14,0,0,"GNAO1;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O",GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0042542//response to hydrogen peroxide;GO:0030900//forebrain development;GO:0006936//muscle contraction;GO:0006184//GTP catabolic process;GO:0034097//response to cytokine;GO:0007212//dopamine receptor signaling pathway;GO:0008016//regulation of heart contraction;GO:0043547//positive regulation of GTPase activity;GO:0031175//neuron projection development;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0043278//response to morphine;GO:0051926//negative regulation of calcium ion transport;GO:0007568//aging;GO:0042493//response to drug;GO:0007626//locomotory behavior,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0051430//corticotropin-releasing hormone receptor 1 binding;GO:0031821//G-protein coupled serotonin receptor binding;GO:0004871//signal transducer activity;GO:0032794//GTPase activating protein binding;GO:0003924//GTPase activity;GO:0031852//mu-type opioid receptor binding;GO:0046872//metal ion binding,K04534//Melanogenesis;Morphine addiction;Toxoplasmosis;Glutamatergic synapse;Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling;Long-term depression;Cholinergic synapse;Chagas disease (American trypanosomiasis);GABAergic synapse;Dopaminergic synapse
2776,0,0,0,28,46,0,0,0,6,1,0,0,"GNAQ;guanine nucleotide binding protein (G protein), q polypeptide",GO:0031965//nuclear membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0048066//developmental pigmentation;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0030168//platelet activation;GO:0009791//post-embryonic development;GO:0007596//blood coagulation;GO:0001501//skeletal system development;GO:0035412//regulation of catenin import into nucleus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0045634//regulation of melanocyte differentiation;GO:0042711//maternal behavior;GO:0021884//forebrain neuron development;GO:0001508//action potential;GO:0016322//neuron remodeling;GO:0006469//negative regulation of protein kinase activity;GO:0007507//heart development;GO:0043547//positive regulation of GTPase activity;GO:0042733//embryonic digit morphogenesis;GO:0006184//GTP catabolic process;GO:0007202//activation of phospholipase C activity;GO:0050821//protein stabilization;GO:0007215//glutamate receptor signaling pathway,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0004871//signal transducer activity;GO:0031826//type 2A serotonin receptor binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding,K04634//Vascular smooth muscle contraction;Glutamatergic synapse;Amoebiasis;Phototransduction - fly;Huntington's disease;Gap junction;Dopaminergic synapse;GnRH signaling pathway;Long-term potentiation;African trypanosomiasis;Pancreatic secretion;Serotonergic synapse;Alzheimer's disease;Melanogenesis;Gastric acid secretion;Long-term depression;Cholinergic synapse;Chagas disease (American trypanosomiasis);Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Retrograde endocannabinoid signaling;Calcium signaling pathway
2778,0,46,3,51,139,0,21,28,17,89,20,0,GNAS;GNAS complex locus,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0032588//trans-Golgi network membrane;GO:0031224//intrinsic component of membrane;GO:0030133//transport vesicle;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0016020//membrane;GO:0005834//heterotrimeric G-protein complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0035264//multicellular organism growth;GO:0007190//activation of adenylate cyclase activity;GO:0006184//GTP catabolic process;GO:0045672//positive regulation of osteoclast differentiation;GO:0050796//regulation of insulin secretion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0055085//transmembrane transport;GO:0042493//response to drug;GO:0040015//negative regulation of multicellular organism growth;GO:0071377//cellular response to glucagon stimulus;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0032320//positive regulation of Ras GTPase activity;GO:0060348//bone development;GO:0007606//sensory perception of chemical stimulus;GO:0071107//response to parathyroid hormone;GO:0001958//endochondral ossification;GO:0071514//genetic imprinting;GO:0006833//water transport;GO:0007608//sensory perception of smell;GO:0070527//platelet aggregation;GO:0071380//cellular response to prostaglandin E stimulus;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0001894//tissue homeostasis;GO:0007565//female pregnancy;GO:0040032//post-embryonic body morphogenesis;GO:0060789//hair follicle placode formation;GO:0035116//embryonic hindlimb morphogenesis;GO:0046907//intracellular transport;GO:0051216//cartilage development;GO:0006171//cAMP biosynthetic process;GO:0007596//blood coagulation;GO:0050890//cognition;GO:0006112//energy reserve metabolic process;GO:0009306//protein secretion;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0071870//cellular response to catecholamine stimulus;GO:0048589//developmental growth;GO:0006306//DNA methylation,GO:0031852//mu-type opioid receptor binding;GO:0035255//ionotropic glutamate receptor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0003924//GTPase activity;GO:0031748//D1 dopamine receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0004871//signal transducer activity;GO:0004016//adenylate cyclase activity;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0051430//corticotropin-releasing hormone receptor 1 binding;GO:0005525//GTP binding,K04632//Chagas disease (American trypanosomiasis);Long-term depression;Endocrine and other factor-regulated calcium reabsorption;Calcium signaling pathway;Dilated cardiomyopathy;Salivary secretion;Gastric acid secretion;Bile secretion;Vibrio cholerae infection;Melanogenesis;Cocaine addiction;Dopaminergic synapse;Gap junction;GnRH signaling pathway;Pancreatic secretion;Serotonergic synapse;Alcoholism;Taste transduction;Amphetamine addiction;Glutamatergic synapse;Morphine addiction;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Amoebiasis
2779,0,0,0,0,0,0,31,0,0,1,0,687,"GNAT1;guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1",GO:0032391//photoreceptor connecting cilium;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0097381//photoreceptor disc membrane;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0042622//photoreceptor outer segment membrane;GO:0016020//membrane,"GO:0071257//cellular response to electrical stimulus;GO:0016056//rhodopsin mediated signaling pathway;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0009642//response to light intensity;GO:0042462//eye photoreceptor cell development;GO:0009416//response to light stimulus;GO:0060041//retina development in camera-type eye;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0050917//sensory perception of umami taste;GO:0007603//phototransduction, visible light;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0006184//GTP catabolic process;GO:0050908//detection of light stimulus involved in visual perception;GO:0008283//cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway",GO:0005525//GTP binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0000035//acyl binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0004871//signal transducer activity;GO:0003924//GTPase activity;GO:0001664//G-protein coupled receptor binding;GO:0046872//metal ion binding,K04631//Carbohydrate digestion and absorption;Phototransduction;Taste transduction
2780,0,0,0,51,19,0,15,0,11,0,20,0,"GNAT2;guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2",GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0042622//photoreceptor outer segment membrane;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane,GO:0046549//retinal cone cell development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050908//detection of light stimulus involved in visual perception;GO:0007602//phototransduction;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006184//GTP catabolic process;GO:0009642//response to light intensity;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007601//visual perception;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0008020//G-protein coupled photoreceptor activity;GO:0001664//G-protein coupled receptor binding;GO:0046872//metal ion binding,K04631//Phototransduction;Taste transduction;Carbohydrate digestion and absorption
2781,0,0,66,0,0,19,0,34,33,0,9,0,"GNAZ;guanine nucleotide binding protein (G protein), alpha z polypeptide",GO:0005834//heterotrimeric G-protein complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005635//nuclear envelope,GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0031821//G-protein coupled serotonin receptor binding;GO:0031683//G-protein beta/gamma-subunit complex binding;GO:0005057//receptor signaling protein activity;GO:0046872//metal ion binding;GO:0004871//signal transducer activity,K04535//Long-term depression
2782,0,247,2,116,380,17,33,0,24,0,3,0,"GNB1;guanine nucleotide binding protein (G protein), beta polypeptide 1",GO:0005622//intracellular;GO:0016020//membrane;GO:0005834//heterotrimeric G-protein complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0097381//photoreceptor disc membrane;GO:0005765//lysosomal membrane;GO:0031982//vesicle,"GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0071870//cellular response to catecholamine stimulus;GO:0007268//synaptic transmission;GO:0006112//energy reserve metabolic process;GO:0016056//rhodopsin mediated signaling pathway;GO:0007596//blood coagulation;GO:0044281//small molecule metabolic process;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0071377//cellular response to glucagon stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0006184//GTP catabolic process",GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0051020//GTPase binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,K04536//Phototransduction;Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Serotonergic synapse;Alcoholism;Retrograde endocannabinoid signaling;Morphine addiction;Taste transduction;Glutamatergic synapse
2783,8,84,1,11,30,10,0,0,15,0,0,0,"GNB2;guanine nucleotide binding protein (G protein), beta polypeptide 2",GO:0048471//perinuclear region of cytoplasm;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0043234//protein complex;GO:0005765//lysosomal membrane;GO:0031982//vesicle;GO:0044297//cell body;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006184//GTP catabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0006112//energy reserve metabolic process;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process,GO:0005246//calcium channel regulator activity;GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0051020//GTPase binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,K04537//Glutamatergic synapse;Morphine addiction;Serotonergic synapse;Alcoholism;Retrograde endocannabinoid signaling;GABAergic synapse;Dopaminergic synapse;Chemokine signaling pathway;Cholinergic synapse
2784,0,0,0,0,0,0,0,0,7,59,13,0,"GNB3;guanine nucleotide binding protein (G protein), beta polypeptide 3",GO:0044297//cell body;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0043005//neuron projection,GO:0007186//G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0007268//synaptic transmission;GO:0008217//regulation of blood pressure;GO:0071377//cellular response to glucagon stimulus;GO:0006112//energy reserve metabolic process;GO:0006184//GTP catabolic process,GO:0051020//GTPase binding;GO:0003924//GTPase activity;GO:0004871//signal transducer activity;GO:0005515//protein binding,K07825//Taste transduction;Glutamatergic synapse;Morphine addiction;GABAergic synapse;Dopaminergic synapse;Chemokine signaling pathway;Cholinergic synapse;Retrograde endocannabinoid signaling;Alcoholism;Serotonergic synapse
2786,0,0,17,18,51,0,1,2,27,0,3,0,"GNG4;guanine nucleotide binding protein (G protein), gamma 4",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0030308//negative regulation of cell growth;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006112//energy reserve metabolic process,GO:0005515//protein binding;GO:0004871//signal transducer activity,K04541//Glutamatergic synapse;Morphine addiction;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Cholinergic synapse;Retrograde endocannabinoid signaling;Alcoholism;Serotonergic synapse
2787,0,0,0,0,0,0,1,0,0,0,0,0,"GNG5;guanine nucleotide binding protein (G protein), gamma 5",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex,GO:0071377//cellular response to glucagon stimulus;GO:0006112//energy reserve metabolic process;GO:0006184//GTP catabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission,GO:0004871//signal transducer activity;GO:0003924//GTPase activity;GO:0030165//PDZ domain binding,K04542//Serotonergic synapse;Alcoholism;Retrograde endocannabinoid signaling;Cholinergic synapse;Chemokine signaling pathway;GABAergic synapse;Dopaminergic synapse;Morphine addiction;Glutamatergic synapse
2788,104,22,0,2,28,9,6,50,14,0,3,0,"GNG7;guanine nucleotide binding protein (G protein), gamma 7",GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0001662//behavioral fear response;GO:0044281//small molecule metabolic process;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0007626//locomotory behavior;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045761//regulation of adenylate cyclase activity;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006112//energy reserve metabolic process,GO:0004871//signal transducer activity,K04543//Morphine addiction;Glutamatergic synapse;Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling
279,0,0,0,0,0,0,0,0,74,0,0,0,"AMY2A;amylase, alpha 2A (pancreatic)",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0016052//carbohydrate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0044245//polysaccharide digestion;GO:0044281//small molecule metabolic process,GO:0004556//alpha-amylase activity;GO:0005509//calcium ion binding;GO:0031404//chloride ion binding,K01176//Carbohydrate digestion and absorption;Salivary secretion;Starch and sucrose metabolism;Pancreatic secretion;Metabolic pathways;Porphyrin and chlorophyll metabolism
2790,0,0,0,2,38,0,0,12,0,164,0,0,"GNG10;guanine nucleotide binding protein (G protein), gamma 10",GO:0005834//heterotrimeric G-protein complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006184//GTP catabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0006112//energy reserve metabolic process,GO:0004871//signal transducer activity;GO:0003924//GTPase activity,K04545//Glutamatergic synapse;Morphine addiction;Alcoholism;Retrograde endocannabinoid signaling;Serotonergic synapse;Chemokine signaling pathway;Dopaminergic synapse;GABAergic synapse;Cholinergic synapse
2791,0,0,0,0,3,0,1,0,0,0,0,0,"GNG11;guanine nucleotide binding protein (G protein), gamma 11",GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane,GO:0006112//energy reserve metabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0006184//GTP catabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004871//signal transducer activity;GO:0003924//GTPase activity,K04546//Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling;Morphine addiction;Glutamatergic synapse
2792,0,0,0,0,0,0,0,0,8,0,0,0,"GNGT1;guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1",GO:0097381//photoreceptor disc membrane;GO:0001917//photoreceptor inner segment;GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane,"GO:0007165//signal transduction;GO:0042462//eye photoreceptor cell development;GO:0071456//cellular response to hypoxia;GO:0010659//cardiac muscle cell apoptotic process;GO:0008104//protein localization;GO:0007268//synaptic transmission;GO:0007603//phototransduction, visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0006184//GTP catabolic process",GO:0003924//GTPase activity;GO:0004871//signal transducer activity,K04548//GABAergic synapse;Dopaminergic synapse;Chemokine signaling pathway;Phototransduction;Cholinergic synapse;Retrograde endocannabinoid signaling;Alcoholism;Serotonergic synapse;Glutamatergic synapse;Morphine addiction
2793,0,0,0,0,0,0,27,0,0,0,0,0,"GNGT2;guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2",GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0006184//GTP catabolic process;GO:0007602//phototransduction;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway,GO:0003924//GTPase activity;GO:0004871//signal transducer activity,K04549//Glutamatergic synapse;Morphine addiction;Alcoholism;Retrograde endocannabinoid signaling;Serotonergic synapse;Chemokine signaling pathway;Dopaminergic synapse;GABAergic synapse;Cholinergic synapse
2794,0,0,0,0,7,0,1,0,0,0,0,0,GNL1;guanine nucleotide binding protein-like 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0006974//cellular response to DNA damage stimulus;GO:0006184//GTP catabolic process;GO:0002456//T cell mediated immunity;GO:0007165//signal transduction;GO:0042254//ribosome biogenesis,GO:0005198//structural molecule activity;GO:0005525//GTP binding;GO:0003924//GTPase activity,K14539//Ribosome biogenesis in eukaryotes
2796,75,0,0,0,0,0,1,53,0,0,0,0,GNRH1;gonadotropin-releasing hormone 1 (luteinizing-releasing hormone),GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0045471//response to ethanol;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0007275//multicellular organismal development;GO:0010468//regulation of gene expression;GO:2000354//regulation of ovarian follicle development;GO:0007165//signal transduction;GO:0042698//ovulation cycle;GO:2001223//negative regulation of neuron migration;GO:0007565//female pregnancy;GO:0007267//cell-cell signaling;GO:0031960//response to corticosteroid,GO:0005179//hormone activity;GO:0005183//gonadotropin hormone-releasing hormone activity,K05252//GnRH signaling pathway
2797,0,0,0,13,0,0,0,0,5,0,0,0,GNRH2;gonadotropin-releasing hormone 2,GO:0005576//extracellular region,GO:0007275//multicellular organismal development;GO:0007165//signal transduction,GO:0005179//hormone activity,K05252//GnRH signaling pathway
2798,0,0,30,5,16,0,9,0,46,1,0,0,GNRHR;gonadotropin-releasing hormone receptor,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0097211//cellular response to gonadotropin-releasing hormone;GO:0007275//multicellular organismal development;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004968//gonadotropin-releasing hormone receptor activity,K04280//GnRH signaling pathway;Neuroactive ligand-receptor interaction
2799,0,0,0,10,6,25,0,84,51,0,4,0,GNS;glucosamine (N-acetyl)-6-sulfatase,GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen,GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0042340//keratan sulfate catabolic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity;GO:0008484//sulfuric ester hydrolase activity,K01137//Lysosome;Metabolic pathways;Glycosaminoglycan degradation
280,0,0,0,0,17,0,0,0,2,0,0,0,"AMY2B;amylase, alpha 2B (pancreatic)",GO:0070062//extracellular vesicular exosome,GO:0007586//digestion;GO:0005975//carbohydrate metabolic process,GO:0004556//alpha-amylase activity;GO:0046872//metal ion binding,K01176//Pancreatic secretion;Starch and sucrose metabolism;Carbohydrate digestion and absorption;Salivary secretion;Porphyrin and chlorophyll metabolism;Metabolic pathways
2800,0,32,0,14,7,0,18,0,44,0,6,169,GOLGA1;golgin A1,GO:0032580//Golgi cisterna membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0048471//perinuclear region of cytoplasm,GO:0000042//protein targeting to Golgi,-,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
2801,71,0,0,0,15,0,37,0,32,121,28,0,GOLGA2;golgin A2,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0005801//cis-Golgi network,GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
2802,0,34,2,27,78,0,11,0,34,22,20,0,GOLGA3;golgin A3,GO:0005730//nucleolus;GO:0032580//Golgi cisterna membrane;GO:0017119//Golgi transport complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0090498//extrinsic component of Golgi membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0006891//intra-Golgi vesicle-mediated transport,GO:0005215//transporter activity;GO:0005515//protein binding,K12478//Phagosome;Endocytosis;Tuberculosis;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
2803,378,85,4,172,283,61,0,161,73,1,142,0,GOLGA4;golgin A4,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0000139//Golgi membrane,GO:0016192//vesicle-mediated transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0000042//protein targeting to Golgi,GO:0005515//protein binding;GO:0051020//GTPase binding,-
2804,0,68,2,87,322,51,117,62,105,0,45,0,GOLGB1;golgin B1,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005801//cis-Golgi network;GO:0005795//Golgi stack;GO:0005794//Golgi apparatus;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0007030//Golgi organization,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
2805,0,0,2,6,6,0,1,0,0,0,0,0,"GOT1;glutamic-oxaloacetic transaminase 1, soluble",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006532//aspartate biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0019550//glutamate catabolic process to aspartate;GO:0006094//gluconeogenesis;GO:0006536//glutamate metabolic process;GO:0051384//response to glucocorticoid;GO:0044281//small molecule metabolic process;GO:0006533//aspartate catabolic process;GO:0055089//fatty acid homeostasis;GO:0008652//cellular amino acid biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006114//glycerol biosynthetic process;GO:0000096//sulfur amino acid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0006531//aspartate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006006//glucose metabolic process;GO:0006595//polyamine metabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate,GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0004609//phosphatidylserine decarboxylase activity;GO:0047801//L-cysteine:2-oxoglutarate aminotransferase activity;GO:0008483//transaminase activity;GO:0031406//carboxylic acid binding;GO:0030170//pyridoxal phosphate binding,"K14454//Isoquinoline alkaloid biosynthesis;Phenylalanine, tyrosine and tryptophan biosynthesis;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Cysteine and methionine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;Tyrosine metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Arginine and proline metabolism;Phenylalanine metabolism"
2806,0,43,4,56,98,33,0,0,30,0,23,312,"GOT2;glutamic-oxaloacetic transaminase 2, mitochondrial",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0005975//carbohydrate metabolic process;GO:0006531//aspartate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0097052//L-kynurenine metabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006006//glucose metabolic process;GO:0019551//glutamate catabolic process to 2-oxoglutarate;GO:0006533//aspartate catabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0015908//fatty acid transport;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006532//aspartate biosynthetic process;GO:0019550//glutamate catabolic process to aspartate;GO:0006094//gluconeogenesis;GO:0006536//glutamate metabolic process;GO:0045471//response to ethanol,GO:0044822//poly(A) RNA binding;GO:0004069//L-aspartate:2-oxoglutarate aminotransferase activity;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0030170//pyridoxal phosphate binding,"K14455//Phenylalanine, tyrosine and tryptophan biosynthesis;Isoquinoline alkaloid biosynthesis;Cysteine and methionine metabolism;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Metabolic pathways;Fat digestion and absorption;Tropane, piperidine and pyridine alkaloid biosynthesis;Alanine, aspartate and glutamate metabolism;Tyrosine metabolism;Phenylalanine metabolism;Arginine and proline metabolism"
280636,0,6,0,6,15,0,22,0,0,0,0,0,C11orf31;chromosome 11 open reading frame 31,-,GO:0045454//cell redox homeostasis,GO:0008430//selenium binding;GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
280655,52,0,0,0,0,0,0,0,0,0,0,0,IGBP1P1;immunoglobulin (CD79A) binding protein 1 pseudogene 1,-,-,-,-
280657,0,0,0,0,0,0,0,0,10,0,0,0,"SSX6;synovial sarcoma, X breakpoint 6 (pseudogene)",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,K15624//Transcriptional misregulation in cancer;K15625//Transcriptional misregulation in cancer
280658,1,0,0,0,0,0,0,0,6,0,0,0,"SSX7;synovial sarcoma, X breakpoint 7",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003676//nucleic acid binding,K15624//Transcriptional misregulation in cancer;K15625//Transcriptional misregulation in cancer
280660,0,0,0,0,0,17,0,0,0,0,0,0,"SSX9;synovial sarcoma, X breakpoint 9",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,K15624//Transcriptional misregulation in cancer;K15625//Transcriptional misregulation in cancer
280664,13,0,0,6,3,0,0,0,4,0,14,0,WFDC10B;WAP four-disulfide core domain 10B,GO:0005576//extracellular region,GO:0010466//negative regulation of peptidase activity,GO:0030414//peptidase inhibitor activity,-
2810,0,11,23,13,29,0,0,59,10,0,0,0,SFN;stratifin,GO:0005829//cytosol;GO:0030659//cytoplasmic vesicle membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010482//regulation of epidermal cell division;GO:0006469//negative regulation of protein kinase activity;GO:0030307//positive regulation of cell growth;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045606//positive regulation of epidermal cell differentiation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0046827//positive regulation of protein export from nucleus;GO:0003334//keratinocyte development;GO:0001836//release of cytochrome c from mitochondria;GO:0007165//signal transduction;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006915//apoptotic process;GO:0061436//establishment of skin barrier;GO:0061024//membrane organization;GO:0031424//keratinization;GO:0010839//negative regulation of keratinocyte proliferation;GO:0071901//negative regulation of protein serine/threonine kinase activity,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0051219//phosphoprotein binding;GO:0019904//protein domain specific binding;GO:0008426//protein kinase C inhibitor activity,K06644//Cell cycle;p53 signaling pathway;Aldosterone-regulated sodium reabsorption
2811,0,0,1,11,42,0,0,24,40,0,19,0,"GP1BA;glycoprotein Ib (platelet), alpha polypeptide",GO:0005887//integral component of plasma membrane;GO:0031362//anchored component of external side of plasma membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0030193//regulation of blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0070493//thrombin receptor signaling pathway;GO:0007596//blood coagulation;GO:0042730//fibrinolysis;GO:0000902//cell morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion",GO:0015057//thrombin receptor activity;GO:0005515//protein binding,K06261//ECM-receptor interaction;Hematopoietic cell lineage
2813,0,0,0,0,11,28,0,3,0,0,5,0,GP2;glycoprotein 2 (zymogen granule membrane),GO:0070062//extracellular vesicular exosome;GO:0031225//anchored component of membrane;GO:0016324//apical plasma membrane,GO:0002412//antigen transcytosis by M cells in mucosal-associated lymphoid tissue,GO:0003823//antigen binding,K01539//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
2814,110,0,0,0,0,16,0,2,75,0,0,0,GP5;glycoprotein V (platelet),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0007160//cell-matrix adhesion;GO:0010544//negative regulation of platelet activation;GO:0007596//blood coagulation;GO:0007597//blood coagulation, intrinsic pathway;GO:0030168//platelet activation;GO:0007155//cell adhesion",GO:0005518//collagen binding,K06260//Hematopoietic cell lineage;ECM-receptor interaction
2815,0,0,0,0,0,0,0,0,1,0,0,0,GP9;glycoprotein IX (platelet),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007596//blood coagulation;GO:0007155//cell adhesion;GO:0030168//platelet activation;GO:0007597//blood coagulation, intrinsic pathway",-,K06263//Hematopoietic cell lineage;ECM-receptor interaction
2817,132,0,1,0,0,10,0,1,17,0,0,0,GPC1;glypican 1,GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane,"GO:0014037//Schwann cell differentiation;GO:0005975//carbohydrate metabolic process;GO:0001523//retinoid metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0007603//phototransduction, visible light;GO:0032288//myelin assembly;GO:0030200//heparan sulfate proteoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007411//axon guidance;GO:2001016//positive regulation of skeletal muscle cell differentiation",GO:0043395//heparan sulfate proteoglycan binding;GO:0043236//laminin binding;GO:0017134//fibroblast growth factor binding;GO:0005507//copper ion binding,-
2819,0,0,0,0,0,0,0,100,10,0,5,0,GPD1;glycerol-3-phosphate dehydrogenase 1 (soluble),GO:0070062//extracellular vesicular exosome;GO:0009331//glycerol-3-phosphate dehydrogenase complex;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0071320//cellular response to cAMP;GO:0046168//glycerol-3-phosphate catabolic process;GO:0006116//NADH oxidation;GO:0006094//gluconeogenesis;GO:0045821//positive regulation of glycolytic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0044281//small molecule metabolic process,GO:0051287//NAD binding;GO:0004367//glycerol-3-phosphate dehydrogenase [NAD+] activity;GO:0042803//protein homodimerization activity;GO:0004368//glycerol-3-phosphate dehydrogenase activity,K00006//Glycerophospholipid metabolism
2820,0,0,0,9,8,18,0,1,30,0,0,0,GPD2;glycerol-3-phosphate dehydrogenase 2 (mitochondrial),GO:0005743//mitochondrial inner membrane;GO:0009331//glycerol-3-phosphate dehydrogenase complex,GO:0006094//gluconeogenesis;GO:0055114//oxidation-reduction process;GO:0035264//multicellular organism growth;GO:0019563//glycerol catabolic process;GO:0006072//glycerol-3-phosphate metabolic process;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0043010//camera-type eye development,GO:0005509//calcium ion binding;GO:0004368//glycerol-3-phosphate dehydrogenase activity;GO:0052591//sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity,K00111//Purine metabolism;Glycerophospholipid metabolism
2821,59,26,2,17,81,17,3,0,36,0,11,88,GPI;glucose-6-phosphate isomerase,GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0006094//gluconeogenesis;GO:0006959//humoral immune response;GO:0046185//aldehyde catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0005975//carbohydrate metabolic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007599//hemostasis;GO:0006006//glucose metabolic process;GO:0019242//methylglyoxal biosynthetic process;GO:0006096//glycolytic process;GO:0001525//angiogenesis;GO:0044281//small molecule metabolic process;GO:0007611//learning or memory,GO:0008083//growth factor activity;GO:0048029//monosaccharide binding;GO:0005125//cytokine activity;GO:0016866//intramolecular transferase activity;GO:0004347//glucose-6-phosphate isomerase activity,K01810//Microbial metabolism in diverse environments;Pentose phosphate pathway;Metabolic pathways;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis
2822,0,0,0,12,0,36,20,0,12,0,31,0,GPLD1;glycosylphosphatidylinositol specific phospholipase D1,GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome,GO:0046470//phosphatidylcholine metabolic process;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0010897//negative regulation of triglyceride catabolic process;GO:0045919//positive regulation of cytolysis;GO:0071467//cellular response to pH;GO:1900076//regulation of cellular response to insulin stimulus;GO:0051047//positive regulation of secretion;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0002430//complement receptor mediated signaling pathway;GO:0070633//transepithelial transport;GO:0043065//positive regulation of apoptotic process;GO:0008286//insulin receptor signaling pathway;GO:0071401//cellular response to triglyceride;GO:0001503//ossification;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006507//GPI anchor release;GO:0071277//cellular response to calcium ion;GO:0009749//response to glucose;GO:0010907//positive regulation of glucose metabolic process;GO:0010983//positive regulation of high-density lipoprotein particle clearance;GO:0035690//cellular response to drug;GO:0032869//cellular response to insulin stimulus;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0010595//positive regulation of endothelial cell migration;GO:0097241//hematopoietic stem cell migration to bone marrow;GO:0071397//cellular response to cholesterol;GO:0002062//chondrocyte differentiation;GO:0008285//negative regulation of cell proliferation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis,GO:0004621//glycosylphosphatidylinositol phospholipase D activity;GO:0004630//phospholipase D activity;GO:0017080//sodium channel regulator activity,K01127//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
28227,0,0,23,0,1,0,0,0,16,170,28,0,"PPP2R3B;protein phosphatase 2, regulatory subunit B'', beta",GO:0005634//nucleus;GO:0000159//protein phosphatase type 2A complex;GO:0005654//nucleoplasm,GO:0006470//protein dephosphorylation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0050790//regulation of catalytic activity;GO:0007050//cell cycle arrest;GO:0000278//mitotic cell cycle,GO:0008601//protein phosphatase type 2A regulator activity;GO:0005509//calcium ion binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,K11583//mRNA surveillance pathway;Dopaminergic synapse
2823,0,0,0,0,0,0,2,0,77,159,0,0,GPM6A;glycoprotein M6A,GO:0030175//filopodium;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0031982//vesicle;GO:0044295//axonal growth cone;GO:0043025//neuronal cell body,GO:0070588//calcium ion transmembrane transport;GO:0048812//neuron projection morphogenesis;GO:0007416//synapse assembly;GO:0051491//positive regulation of filopodium assembly;GO:0048863//stem cell differentiation;GO:0001764//neuron migration;GO:0003407//neural retina development,GO:0005515//protein binding;GO:0005262//calcium channel activity,-
28231,9,0,0,0,0,0,0,0,3,0,10,0,"SLCO4A1;solute carrier organic anion transporter family, member 4A1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0043252//sodium-independent organic anion transport,GO:0005215//transporter activity,-
28232,0,0,0,0,0,42,0,0,41,0,0,0,"SLCO3A1;solute carrier organic anion transporter family, member 3A1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
28234,0,0,0,0,0,0,23,1,2,0,0,0,"SLCO1B3;solute carrier organic anion transporter family, member 1B3",GO:0005887//integral component of plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane,GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0008206//bile acid metabolic process;GO:0044281//small molecule metabolic process;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport,GO:0008514//organic anion transmembrane transporter activity,K05043//Bile secretion
2824,0,0,0,3,0,21,1,0,22,0,0,0,GPM6B;glycoprotein M6B,GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0030154//cell differentiation;GO:2000009//negative regulation of protein localization to cell surface;GO:0001503//ossification;GO:0085029//extracellular matrix assembly;GO:0051612//negative regulation of serotonin uptake;GO:0030501//positive regulation of bone mineralization;GO:0051893//regulation of focal adhesion assembly;GO:0032956//regulation of actin cytoskeleton organization;GO:0015031//protein transport;GO:0007399//nervous system development,-,-
2825,0,0,0,0,0,35,24,0,17,0,0,0,GPR1;G protein-coupled receptor 1,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
2826,0,0,0,0,0,0,0,0,29,0,2,0,CCR10;chemokine (C-C motif) receptor 10,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070098//chemokine-mediated signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0016493//C-C chemokine receptor activity,K04185//Intestinal immune network for IgA production;Chemokine signaling pathway;Cytokine-cytokine receptor interaction
282616,0,9,0,0,0,0,0,91,10,0,0,0,"IFNL2;interferon, lambda 2",GO:0005615//extracellular space,GO:0007259//JAK-STAT cascade;GO:0002385//mucosal immune response;GO:0051607//defense response to virus;GO:0050778//positive regulation of immune response,GO:0005125//cytokine activity,K05447//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
282617,0,0,0,0,0,0,0,0,30,0,1,0,"IFNL3;interferon, lambda 3",GO:0005615//extracellular space,GO:0007259//JAK-STAT cascade;GO:0045071//negative regulation of viral genome replication;GO:0050778//positive regulation of immune response;GO:0051607//defense response to virus,GO:0005125//cytokine activity,K05447//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
282618,87,0,0,0,0,0,0,0,0,0,0,0,"IFNL1;interferon, lambda 1",GO:0032002//interleukin-28 receptor complex;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0032696//negative regulation of interleukin-13 production;GO:0007259//JAK-STAT cascade;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032729//positive regulation of interferon-gamma production;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0051607//defense response to virus;GO:0050778//positive regulation of immune response;GO:0046427//positive regulation of JAK-STAT cascade;GO:0008285//negative regulation of cell proliferation;GO:0032714//negative regulation of interleukin-5 production;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0002829//negative regulation of type 2 immune response;GO:0043381//negative regulation of memory T cell differentiation;GO:0045581//negative regulation of T cell differentiation",GO:0032003//interleukin-28 receptor binding;GO:0005125//cytokine activity;GO:0005102//receptor binding,K05447//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
282679,0,0,0,8,0,0,0,0,60,0,0,0,AQP11;aquaporin 11,GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0015840//urea transport;GO:0072014//proximal tubule development;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0048388//endosomal lumen acidification;GO:0015793//glycerol transport;GO:0051260//protein homooligomerization;GO:0006833//water transport,GO:0005215//transporter activity,-
2827,0,0,0,0,0,0,6,0,35,0,0,0,GPR3;G protein-coupled receptor 3,GO:0005887//integral component of plasma membrane,GO:0040020//regulation of meiosis;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding,-
282763,66,0,0,0,0,0,0,1,0,0,0,0,"OR51B5;olfactory receptor, family 51, subfamily B, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
282770,0,0,0,0,0,0,0,0,33,0,0,0,"OR10AG1;olfactory receptor, family 10, subfamily AG, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
282775,0,0,0,0,0,0,0,0,5,0,0,0,"OR5J2;olfactory receptor, family 5, subfamily J, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2828,0,0,0,0,0,0,0,0,18,0,8,0,GPR4;G protein-coupled receptor 4,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
282808,58,0,0,0,0,0,0,0,33,0,7,0,"RAB40AL;RAB40A, member RAS oncogene family-like",GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0016567//protein ubiquitination;GO:0015031//protein transport,GO:0005525//GTP binding,-
282809,0,0,0,20,19,0,0,0,0,0,0,0,POC1B;POC1 centriolar protein B,GO:0036064//ciliary basal body;GO:0005814//centriole;GO:0005813//centrosome;GO:0000922//spindle pole,GO:0042384//cilium assembly;GO:0008283//cell proliferation,GO:0005515//protein binding,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis;K03130//Herpes simplex infection;Basal transcription factors;K01062//Metabolic pathways;Ether lipid metabolism;Biosynthesis of secondary metabolites
282890,0,0,0,0,0,0,9,0,0,0,0,0,ZNF311;zinc finger protein 311,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
2829,0,0,0,0,0,1,21,0,0,0,0,0,XCR1;chemokine (C motif) receptor 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0007186//G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070098//chemokine-mediated signaling pathway;GO:0006954//inflammatory response;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0006935//chemotaxis;GO:0051209//release of sequestered calcium ion into cytosol",GO:0004950//chemokine receptor activity,K04193//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
282966,0,0,0,0,0,0,0,0,12,0,0,0,C10orf53;chromosome 10 open reading frame 53,-,-,-,-
282973,30,0,0,0,9,19,22,1,68,0,42,0,JAKMIP3;Janus kinase and microtubule interacting protein 3,GO:0005794//Golgi apparatus,-,GO:0019900//kinase binding;GO:0008017//microtubule binding,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
282974,0,0,0,0,0,0,20,1,34,0,0,1,STK32C;serine/threonine kinase 32C,-,GO:0006468//protein phosphorylation,GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
282991,0,23,0,12,22,0,0,0,13,237,7,0,"BLOC1S2;biogenesis of lysosomal organelles complex-1, subunit 2",GO:0055037//recycling endosome;GO:0005634//nucleus;GO:0005813//centrosome;GO:0031083//BLOC-1 complex;GO:0000930//gamma-tubulin complex;GO:0005739//mitochondrion,"GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0097345//mitochondrial outer membrane permeabilization;GO:0008089//anterograde axon cargo transport;GO:0031175//neuron projection development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0060155//platelet dense granule organization;GO:0007020//microtubule nucleation",GO:0008022//protein C-terminus binding;GO:0043015//gamma-tubulin binding;GO:0005515//protein binding,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
282996,0,0,0,0,0,27,0,0,35,0,30,1,RBM20;RNA binding motif protein 20,GO:0005634//nucleus,GO:0007507//heart development;GO:0006397//mRNA processing;GO:0033120//positive regulation of RNA splicing;GO:0008380//RNA splicing,GO:0000166//nucleotide binding;GO:0008270//zinc ion binding;GO:0003723//RNA binding,-
283,0,28,0,0,0,0,0,0,0,0,7,0,"ANG;angiogenin, ribonuclease, RNase A family, 5",GO:0005634//nucleus;GO:0005615//extracellular space;GO:0032311//angiogenin-PRI complex;GO:0005730//nucleolus;GO:0030426//growth cone;GO:0043025//neuronal cell body;GO:0005605//basal lamina;GO:0070062//extracellular vesicular exosome,GO:0009303//rRNA transcription;GO:0030041//actin filament polymerization;GO:0001556//oocyte maturation;GO:0001890//placenta development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007202//activation of phospholipase C activity;GO:0007154//cell communication;GO:0008219//cell death;GO:0032431//activation of phospholipase A2 activity;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006651//diacylglycerol biosynthetic process;GO:0042592//homeostatic process;GO:0042327//positive regulation of phosphorylation;GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0001541//ovarian follicle development;GO:0050714//positive regulation of protein secretion;GO:0032148//activation of protein kinase B activity;GO:0016477//cell migration;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0009725//response to hormone;GO:0017148//negative regulation of translation,GO:0003677//DNA binding;GO:0019843//rRNA binding;GO:0003779//actin binding;GO:0008201//heparin binding;GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0004540//ribonuclease activity;GO:0005102//receptor binding;GO:0042277//peptide binding;GO:0005507//copper ion binding,-
2830,0,0,0,0,0,0,0,1,0,0,0,0,GPR6;G protein-coupled receptor 6,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
283011,0,0,0,0,0,5,0,0,7,0,0,0,FLJ37201;tigger transposable element derived 2 pseudogene,-,-,-,-
283078,0,0,0,0,0,0,0,0,13,71,4,0,MKX;mohawk homeobox,GO:0005634//nucleus,GO:0002932//tendon sheath development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045662//negative regulation of myoblast differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0035990//tendon cell differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0030199//collagen fibril organization;GO:0006366//transcription from RNA polymerase II promoter,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001085//RNA polymerase II transcription factor binding,K15613//Transcriptional misregulation in cancer
283080,0,0,0,0,0,0,25,0,33,0,0,0,C10orf126;chromosome 10 open reading frame 126,-,-,-,-
283092,0,0,0,0,0,27,0,0,0,0,0,0,"OR4C13;olfactory receptor, family 4, subfamily C, member 13",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
2831,1,0,0,0,0,0,0,0,0,0,0,0,NPBWR1;neuropeptides B/W receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0019222//regulation of metabolic process;GO:0007218//neuropeptide signaling pathway;GO:0038003//opioid receptor signaling pathway,GO:0004985//opioid receptor activity;GO:0008188//neuropeptide receptor activity;GO:0005515//protein binding,K05268//Neuroactive ligand-receptor interaction
283102,0,0,0,0,0,23,0,8,28,0,0,0,KRT8P41;keratin 8 pseudogene 41,-,-,-,-
283104,0,149,52,135,182,0,70,115,21,1,246,187,SBF2-AS1;SBF2 antisense RNA 1,-,-,-,-
283106,0,0,0,5,7,0,0,0,0,0,5,0,"CSNK2A3;casein kinase 2, alpha 3 polypeptide",-,-,-,K03097//Epstein-Barr virus infection;Ribosome biogenesis in eukaryotes;Measles;Adherens junction;Wnt signaling pathway;Herpes simplex infection;Circadian rhythm - plant;NF-kappa B signaling pathway;Tight junction
283116,0,0,0,0,0,0,0,0,9,0,0,0,TRIM49B;tripartite motif containing 49B,-,-,-,-
283120,0,0,0,0,0,0,0,0,9,0,0,0,"H19;H19, imprinted maternally expressed transcript (non-protein coding)",-,-,-,-
283129,0,0,0,0,0,0,0,0,4,0,0,0,C11orf85;chromosome 11 open reading frame 85,-,-,-,-
283130,0,0,0,0,0,15,3,0,7,0,0,0,"SLC25A45;solute carrier family 25, member 45",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
283149,104,0,0,0,6,9,16,0,58,0,0,22,BCL9L;B-cell CLL/lymphoma 9-like,GO:0005634//nucleus,"GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0022604//regulation of cell morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0035019//somatic stem cell maintenance;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0008013//beta-catenin binding,-
283150,0,0,0,0,0,26,0,0,4,0,0,0,FOXR1;forkhead box R1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
283152,1,0,0,0,0,0,0,0,50,0,0,0,CCDC153;coiled-coil domain containing 153,-,-,-,K03521//Nitrogen metabolism
283159,0,0,0,0,0,0,0,0,0,0,3,0,"OR8D1;olfactory receptor, family 8, subfamily D, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
28316,0,0,0,0,15,0,53,68,26,0,0,0,"CDH20;cadherin 20, type 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
283165,0,0,0,0,0,0,15,102,3,0,0,0,KIRREL3-AS3;KIRREL3 antisense RNA 3,-,-,-,-
283171,0,0,0,0,0,0,0,29,11,0,0,0,C11orf44;chromosome 11 open reading frame 44,GO:0005576//extracellular region,-,-,K06264//ECM-receptor interaction
283174,0,0,0,0,0,26,0,0,27,1,0,0,MIR4697HG;MIR4697 host gene (non-protein coding),-,-,-,-
283177,0,0,0,0,0,40,0,0,9,0,0,184,LOC283177;uncharacterized LOC283177,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
283194,60,0,0,0,0,0,0,0,32,0,0,0,LOC283194;uncharacterized LOC283194,-,-,-,-
2832,0,0,0,0,0,0,0,0,17,0,0,0,NPBWR2;neuropeptides B/W receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0038003//opioid receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004985//opioid receptor activity;GO:0008188//neuropeptide receptor activity;GO:0005515//protein binding,K08377//Neuroactive ligand-receptor interaction
283208,0,0,0,0,0,0,0,0,16,80,0,0,"P4HA3;prolyl 4-hydroxylase, alpha polypeptide III",GO:0005788//endoplasmic reticulum lumen,GO:0019511//peptidyl-proline hydroxylation;GO:0055114//oxidation-reduction process,"GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding;GO:0005506//iron ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",K00472//Arginine and proline metabolism;Metabolic pathways
283209,103,36,0,26,36,11,58,0,77,0,0,0,PGM2L1;phosphoglucomutase 2-like 1,GO:0005829//cytosol,GO:0016310//phosphorylation;GO:0019388//galactose catabolic process;GO:0005978//glycogen biosynthetic process;GO:0006006//glucose metabolic process,"GO:0004614//phosphoglucomutase activity;GO:0047933//glucose-1,6-bisphosphate synthase activity",K11809//Starch and sucrose metabolism
283212,70,0,0,0,0,0,0,0,18,0,0,0,KLHL35;kelch-like family member 35,-,-,-,-
283214,0,0,0,0,0,0,0,0,10,0,0,0,LOC283214;uncharacterized LOC283214,-,-,-,K11160//Fat digestion and absorption;Metabolic pathways;Glycerolipid metabolism;K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
283219,0,11,0,13,4,14,0,3,35,0,50,0,KCTD21;potassium channel tetramerization domain containing 21,-,GO:0051260//protein homooligomerization,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
283229,0,0,0,0,0,0,0,65,15,0,0,0,CRACR2B;calcium release activated channel regulator 2B,GO:0005737//cytoplasm,GO:0002115//store-operated calcium entry;GO:2001256//regulation of store-operated calcium entry;GO:0034613//cellular protein localization,GO:0005509//calcium ion binding,-
283232,0,0,0,2,0,0,8,0,36,0,2,0,TMEM80;transmembrane protein 80,GO:0016021//integral component of membrane,-,-,-
283234,70,0,1,0,0,0,23,31,17,148,0,0,CCDC88B;coiled-coil domain containing 88B,GO:0016020//membrane,-,-,K13911//Salivary secretion
283237,0,0,1,3,0,0,0,0,0,0,0,0,TTC9C;tetratricopeptide repeat domain 9C,-,-,-,-
283238,0,0,0,0,0,5,0,0,22,0,0,0,"SLC22A24;solute carrier family 22, member 24",GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0055085//transmembrane transport,-,-
283248,0,0,0,0,0,0,0,0,38,0,2,0,RCOR2;REST corepressor 2,GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0000785//chromatin,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K11829//Huntington's disease
283254,0,0,0,0,7,0,0,55,0,0,0,3,HARBI1;harbinger transposase derived 1,GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004518//nuclease activity;GO:0046872//metal ion binding,-
283284,0,0,0,0,0,0,9,0,54,0,18,3,"IGSF22;immunoglobulin superfamily, member 22",-,-,-,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
283297,82,0,0,0,0,0,0,0,0,0,0,0,"OR10A4;olfactory receptor, family 10, subfamily A, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007411//axon guidance,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
283298,0,0,0,0,0,9,0,0,17,0,0,0,OLFML1;olfactomedin-like 1,GO:0005576//extracellular region,-,-,-
2833,0,0,0,0,0,4,0,107,0,0,0,0,CXCR3;chemokine (C-X-C motif) receptor 3,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0050921//positive regulation of chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0045766//positive regulation of angiogenesis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0002685//regulation of leukocyte migration;GO:0008284//positive regulation of cell proliferation;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0030816//positive regulation of cAMP metabolic process;GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:1900118//negative regulation of execution phase of apoptosis;GO:0010818//T cell chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:0006935//chemotaxis;GO:0071954//chemokine (C-C motif) ligand 11 production;GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016525//negative regulation of angiogenesis;GO:0006954//inflammatory response;GO:0019722//calcium-mediated signaling;GO:0001937//negative regulation of endothelial cell proliferation;GO:1900119//positive regulation of execution phase of apoptosis,GO:0016494//C-X-C chemokine receptor activity;GO:0004872//receptor activity;GO:0019956//chemokine binding;GO:0019958//C-X-C chemokine binding;GO:0004950//chemokine receptor activity,K04188//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
283303,0,0,0,0,0,0,0,0,46,0,9,0,MRGPRG-AS1;MRGPRG antisense RNA 1,-,-,-,-
283310,0,0,0,0,0,46,49,45,92,173,8,275,OTOGL;otogelin-like,GO:0005576//extracellular region,GO:0046373//L-arabinose metabolic process,GO:0046556//alpha-L-arabinofuranosidase activity,K03900//ECM-receptor interaction;Complement and coagulation cascades;Focal adhesion
283335,0,0,29,6,82,0,0,240,24,0,107,0,LOC283335;uncharacterized LOC283335,-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
283337,24,31,1,12,100,0,0,30,10,0,10,213,ZNF740;zinc finger protein 740,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
283345,0,0,0,0,0,35,0,0,2,0,0,0,RPL13P5;ribosomal protein L13 pseudogene 5,-,-,-,K02873//Ribosome
283349,0,147,1,50,104,12,0,0,2,0,0,0,RASSF3;Ras association (RalGDS/AF-6) domain family member 3,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007165//signal transduction,GO:0042802//identical protein binding;GO:0005515//protein binding,-
283358,0,0,0,0,0,16,10,4,28,0,4,0,"B4GALNT3;beta-1,4-N-acetyl-galactosaminyl transferase 3",GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0008152//metabolic process,GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity,-
283373,185,33,0,0,21,25,6,0,89,0,13,582,ANKRD52;ankyrin repeat domain 52,-,-,GO:0005515//protein binding,-
283375,0,29,0,0,1,0,0,27,18,0,0,0,"SLC39A5;solute carrier family 39 (zinc transporter), member 5",GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006829//zinc ion transport;GO:0055085//transmembrane transport;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0061351//neural precursor cell proliferation,GO:0046873//metal ion transmembrane transporter activity,-
283377,0,0,0,0,0,0,1,0,4,0,1,0,SPRYD4;SPRY domain containing 4,GO:0005634//nucleus;GO:0005739//mitochondrion,-,-,K11447//Transcriptional misregulation in cancer;K08285//Ubiquitin mediated proteolysis
283383,89,0,0,0,0,31,48,81,74,14,16,0,GPR133;G protein-coupled receptor 133,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
283385,115,0,0,0,0,0,0,0,0,0,0,0,MORN3;MORN repeat containing 3,GO:0005634//nucleus,-,-,K04575//Amyotrophic lateral sclerosis (ALS)
283392,0,0,0,0,0,0,58,0,0,0,0,0,TRHDE-AS1;TRHDE antisense RNA 1,-,-,-,-
2834,0,0,0,0,0,14,23,0,19,0,0,0,PRLHR;prolactin releasing hormone receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0042445//hormone metabolic process;GO:0007565//female pregnancy;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding;GO:0004983//neuropeptide Y receptor activity;GO:0008188//neuropeptide receptor activity,K04314//Neuroactive ligand-receptor interaction
283416,0,0,0,0,0,17,4,0,0,0,0,0,C12orf61;chromosome 12 open reading frame 61,-,-,-,-
283417,0,0,0,0,0,0,0,0,44,0,14,0,DPY19L2;dpy-19-like 2 (C. elegans),GO:0016021//integral component of membrane;GO:0005637//nuclear inner membrane;GO:0005634//nucleus,GO:0007286//spermatid development;GO:0008152//metabolic process;GO:0007275//multicellular organismal development,"GO:0016757//transferase activity, transferring glycosyl groups",-
283431,0,0,0,0,0,9,0,0,38,0,0,0,GAS2L3;growth arrest-specific 2 like 3,GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0015629//actin cytoskeleton,GO:0000226//microtubule cytoskeleton organization;GO:0007050//cell cycle arrest;GO:0030036//actin cytoskeleton organization,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003779//actin binding,-
283440,0,0,0,0,9,0,0,0,7,0,10,241,LOC283440;uncharacterized LOC283440,-,-,-,-
283446,0,0,0,0,20,27,45,0,13,0,1,0,MYO1H;myosin IH,GO:0016459//myosin complex,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0003779//actin binding;GO:0003774//motor activity,-
283450,8,24,1,91,171,38,70,20,239,116,40,0,HECTD4;HECT domain containing E3 ubiquitin protein ligase 4,GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0042593//glucose homeostasis;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006006//glucose metabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K10594//Ubiquitin mediated proteolysis;K10595//Ubiquitin mediated proteolysis
283455,217,22,0,0,0,31,5,97,50,0,1,0,KSR2;kinase suppressor of ras 2,GO:0005737//cytoplasm;GO:0016020//membrane,GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity,K14958//Tuberculosis
283459,194,2788,2793,3590,5309,0,207,739,164,190,3793,276,"GATC;glutamyl-tRNA(Gln) amidotransferase, subunit C",GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex;GO:0005739//mitochondrion,GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation;GO:0032543//mitochondrial translation;GO:0006450//regulation of translational fidelity,GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity;GO:0005524//ATP binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K11447//Transcriptional misregulation in cancer
283461,0,0,0,0,0,46,0,106,0,190,15,0,C12orf40;chromosome 12 open reading frame 40,-,-,-,-
283463,55,0,0,0,0,23,97,146,294,426,27,1,"MUC19;mucin 19, oligomeric",GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome,GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,-,K10955//Amoebiasis;Vibrio cholerae infection
283464,0,0,0,0,3,20,0,0,37,0,0,0,GXYLT1;glucoside xylosyltransferase 1,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0016266//O-glycan processing;GO:0005975//carbohydrate metabolic process,GO:0035252//UDP-xylosyltransferase activity,K13676//Other types of O-glycan biosynthesis
283471,0,0,0,0,0,50,0,1,0,0,13,0,"TMPRSS12;transmembrane (C-terminal) protease, serine 12",GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
283487,72,0,0,0,0,0,0,0,0,0,0,0,LINC00346;long intergenic non-protein coding RNA 346,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
283489,0,0,0,1,27,0,43,0,8,0,0,0,CHAMP1;chromosome alignment maintaining phosphoprotein 1,GO:0000777//condensed chromosome kinetochore;GO:0000793//condensed chromosome;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0031134//sister chromatid biorientation;GO:0035372//protein localization to microtubule;GO:0034501//protein localization to kinetochore;GO:0051315//attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation,GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
2835,104,0,0,0,0,0,25,0,19,0,0,1,GPR12;G protein-coupled receptor 12,GO:0005887//integral component of plasma membrane,GO:0006874//cellular calcium ion homeostasis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0031210//phosphatidylcholine binding;GO:0004930//G-protein coupled receptor activity,-
283514,0,76,94,14,1,0,9,101,8,0,9,0,SIAH3;siah E3 ubiquitin protein ligase family member 3,GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007275//multicellular organismal development,GO:0046872//metal ion binding,K04506//Wnt signaling pathway;p53 signaling pathway;Ubiquitin mediated proteolysis
283521,0,0,0,0,0,0,0,92,0,0,0,0,LINC00282;long intergenic non-protein coding RNA 282,-,-,-,-
283537,0,0,0,0,0,0,0,0,17,0,1,0,"SLC46A3;solute carrier family 46, member 3",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,K14613//Vitamin digestion and absorption;Mineral absorption
283547,1,0,0,0,5,0,7,78,19,0,0,1,LINC00639;long intergenic non-protein coding RNA 639,-,-,-,-
283554,0,0,0,0,0,0,0,0,4,0,0,0,GPR137C;G protein-coupled receptor 137C,GO:0016021//integral component of membrane,-,-,-
283571,0,0,0,45,19,0,31,0,0,157,14,0,PROX2;prospero homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
283576,0,0,0,0,0,0,0,0,0,0,10,0,"ZDHHC22;zinc finger, DHHC-type containing 22",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0072659//protein localization to plasma membrane;GO:0018345//protein palmitoylation,GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,-
283578,31,27,0,0,7,0,0,0,13,0,0,0,TMED8;transmembrane emp24 protein transport domain containing 8,GO:0016021//integral component of membrane,GO:0006810//transport,-,-
283579,0,22,0,51,2,0,0,0,6,1,16,0,C14orf178;chromosome 14 open reading frame 178,-,-,-,K01530//Purine metabolism
283598,0,0,0,0,0,0,0,0,39,0,10,0,C14orf177;chromosome 14 open reading frame 177,-,-,-,-
283600,0,0,0,0,0,0,0,1,16,0,7,0,"SLC25A47;solute carrier family 25, member 47",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport,-,-
283601,0,0,0,0,0,0,0,36,35,0,1,0,LINC00523;long intergenic non-protein coding RNA 523,-,-,-,-
283629,34,85,30,35,85,30,12,0,54,0,33,0,TSSK4;testis-specific serine kinase 4,-,GO:0007283//spermatogenesis;GO:0032793//positive regulation of CREB transcription factor activity;GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
283635,1,68,48,96,57,0,9,147,67,0,61,0,"FAM177A1;family with sequence similarity 177, member A1",-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K11447//Transcriptional misregulation in cancer
283638,0,23,2,5,10,4,33,59,70,108,0,1,CEP170B;centrosomal protein 170B,GO:0005874//microtubule;GO:0005737//cytoplasm,-,-,-
283643,0,0,0,0,0,0,0,0,2,0,26,0,C14orf80;chromosome 14 open reading frame 80,-,-,-,-
283651,0,118,92,252,380,0,0,0,0,0,310,0,HMGN2P46;high mobility group nucleosomal binding domain 2 pseudogene 46,-,-,-,-
283652,0,0,99,79,189,12,0,0,8,0,26,0,"SLC24A5;solute carrier family 24 (sodium/potassium/calcium exchanger), member 5",GO:0005802//trans-Golgi network;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0042470//melanosome,GO:0048022//negative regulation of melanin biosynthetic process;GO:0050896//response to stimulus;GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006811//ion transport;GO:0035725//sodium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0055085//transmembrane transport,"GO:0015293//symporter activity;GO:0008273//calcium, potassium:sodium antiporter activity",-
283659,0,0,51,0,0,18,26,0,86,0,13,0,PRTG;protogenin,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0007275//multicellular organismal development,-,K06765//Pathways in cancer;Axon guidance;Colorectal cancer;K06766//Cell adhesion molecules (CAMs)
283677,0,0,0,0,0,0,0,0,20,0,0,0,REC114;REC114 meiotic recombination protein,-,GO:0007126//meiotic nuclear division;GO:0006310//DNA recombination,-,-
283693,69,0,0,0,0,0,0,0,25,0,8,0,"LOC283693;actin, alpha 2, smooth muscle, aorta pseudogene",-,-,-,K05692//Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Influenza A;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phototransduction - fly;Adherens junction;Viral myocarditis
283694,0,0,0,0,0,24,22,0,0,0,0,0,"OR4N4;olfactory receptor, family 4, subfamily N, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
2837,0,0,0,0,0,0,0,31,0,0,0,0,UTS2R;urotensin 2 receptor,GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0055037//recycling endosome,"GO:0003105//negative regulation of glomerular filtration;GO:0042493//response to drug;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045766//positive regulation of angiogenesis;GO:0048146//positive regulation of fibroblast proliferation;GO:0045777//positive regulation of blood pressure;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010841//positive regulation of circadian sleep/wake cycle, wakefulness;GO:0030307//positive regulation of cell growth;GO:0008015//blood circulation;GO:0007165//signal transduction;GO:0045776//negative regulation of blood pressure;GO:0035814//negative regulation of renal sodium excretion;GO:0045907//positive regulation of vasoconstriction;GO:0042312//regulation of vasodilation;GO:0035811//negative regulation of urine volume;GO:0046005//positive regulation of circadian sleep/wake cycle, REM sleep",GO:0004930//G-protein coupled receptor activity;GO:0001604//urotensin II receptor activity,K04241//Neuroactive ligand-receptor interaction
283726,0,0,0,0,0,23,23,0,55,0,0,0,"FAM154B;family with sequence similarity 154, member B",-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K13711//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
283742,0,0,0,0,35,0,16,0,45,0,0,0,"FAM98B;family with sequence similarity 98, member B",GO:0072669//tRNA-splicing ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0044822//poly(A) RNA binding,-
283748,0,0,0,0,9,0,11,92,58,0,11,0,"PLA2G4D;phospholipase A2, group IVD (cytosolic)",GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol,GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006654//phosphatidic acid biosynthetic process;GO:0009395//phospholipid catabolic process,GO:0004623//phospholipase A2 activity;GO:0046872//metal ion binding,K01047//GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;Metabolic pathways;Vascular smooth muscle contraction;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism
283755,0,0,0,0,0,53,2,0,45,0,0,0,HERC2P3;hect domain and RLD 2 pseudogene 3,-,GO:0016567//protein ubiquitination,GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity,K10595//Ubiquitin mediated proteolysis
283767,0,0,0,0,0,0,0,0,2,12,0,0,GOLGA6L1;golgin A6 family-like 1,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption
283768,0,0,0,0,0,1,0,0,0,0,0,0,"GOLGA8G;golgin A8 family, member G",GO:0005794//Golgi apparatus,-,-,-
283777,0,0,0,0,0,20,3,0,38,0,0,0,"FAM169B;family with sequence similarity 169, member B",-,-,-,-
283788,0,0,0,0,0,0,0,0,39,0,4,0,LOC283788;FSHD region gene 1 pseudogene,-,-,-,-
283796,0,0,0,0,0,0,0,54,1,1,0,6,"GOLGA8I;golgin A8 family, member I",GO:0032580//Golgi cisterna membrane,-,-,-
2838,0,0,0,0,0,0,0,0,0,0,0,337,GPR15;G protein-coupled receptor 15,GO:0005887//integral component of plasma membrane,GO:0072678//T cell migration;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
283807,0,0,0,0,0,0,0,0,22,0,0,0,FBXL22;F-box and leucine-rich repeat protein 22,GO:0030018//Z disc,GO:0016567//protein ubiquitination,-,-
283820,0,0,1,5,0,0,1,0,29,1,0,3,NOMO2;NODAL modulator 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,-,GO:0030246//carbohydrate binding;GO:0005515//protein binding,-
283847,0,0,0,0,0,26,0,0,59,0,0,0,CCDC79;coiled-coil domain containing 79,"GO:0000781//chromosome, telomeric region",GO:0007129//synapsis;GO:0045141//meiotic telomere clustering,GO:0003682//chromatin binding;GO:0003677//DNA binding,-
283848,0,29,0,0,0,0,41,81,18,0,0,0,CES4A;carboxylesterase 4A,GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,K01044//Metabolic pathways;Drug metabolism - other enzymes
283849,31,41,147,0,50,24,0,509,58,113,214,0,EXOC3L1;exocyst complex component 3-like 1,GO:0000145//exocyst;GO:0030133//transport vesicle;GO:0030141//secretory granule,GO:0030072//peptide hormone secretion;GO:0006887//exocytosis,-,K06110//Tight junction
283860,0,0,0,0,0,0,0,0,4,0,0,0,LINC00304;long intergenic non-protein coding RNA 304,-,-,-,-
283869,0,0,0,0,0,0,28,0,0,0,0,0,NPW;neuropeptide W,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0001664//G-protein coupled receptor binding,K13358//Aldosterone-regulated sodium reabsorption
283870,108,107,104,103,137,0,26,68,15,0,439,3,BRICD5;BRICHOS domain containing 5,GO:0016021//integral component of membrane,-,-,K01091//Biosynthesis of secondary metabolites;Homologous recombination;Ribosome;Phosphonate and phosphinate metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Microbial metabolism in diverse environments
283871,0,0,0,0,0,0,0,0,8,0,0,0,PGP;phosphoglycolate phosphatase,-,GO:0005975//carbohydrate metabolic process;GO:0016311//dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,"GO:0008967//phosphoglycolate phosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:0000287//magnesium ion binding;GO:0004725//protein tyrosine phosphatase activity",K01091//Biosynthesis of secondary metabolites;Homologous recombination;Ribosome;Phosphonate and phosphinate metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Microbial metabolism in diverse environments
283876,0,0,0,0,0,4,0,0,0,0,0,0,LINC00921;long intergenic non-protein coding RNA 921,-,-,-,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
283897,0,0,0,35,0,0,0,13,18,0,39,0,C16orf54;chromosome 16 open reading frame 54,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
283899,0,0,0,0,0,0,0,0,5,26,0,0,INO80E;INO80 complex subunit E,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0031011//Ino80 complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0006310//DNA recombination",GO:0005515//protein binding,-
283922,69,40,0,0,0,14,20,26,27,0,20,0,LOC283922;pyruvate dehydrogenase phosphatase regulatory subunit pseudogene,-,-,-,"K00314//Glycine, serine and threonine metabolism;Metabolic pathways"
283927,0,0,0,0,1,0,0,0,29,0,0,0,NUDT7;nudix (nucleoside diphosphate linked moiety X)-type motif 7,GO:0005777//peroxisome,GO:0050873//brown fat cell differentiation;GO:0009132//nucleoside diphosphate metabolic process;GO:0046356//acetyl-CoA catabolic process;GO:0015938//coenzyme A catabolic process,GO:0050072//m7G(5')pppN diphosphatase activity;GO:0005102//receptor binding;GO:0000287//magnesium ion binding;GO:0003986//acetyl-CoA hydrolase activity;GO:0030515//snoRNA binding;GO:0030145//manganese ion binding,K12756//Tight junction;Regulation of actin cytoskeleton;Focal adhesion;Leukocyte transendothelial migration;K01529//Purine metabolism
283933,0,0,0,0,0,0,0,0,6,0,0,0,ZNF843;zinc finger protein 843,-,-,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
283951,0,0,0,0,0,9,0,0,16,0,0,0,C16orf91;chromosome 16 open reading frame 91,GO:0016021//integral component of membrane,-,-,K10087//Lysosome
283953,87,0,0,0,0,0,0,0,43,0,0,0,TMEM114;transmembrane protein 114,GO:0016327//apicolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane,-,-,K04869//Dilated cardiomyopathy;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
283970,0,0,0,0,0,12,0,1,30,4,18,0,"PDXDC2P;pyridoxal-dependent decarboxylase domain containing 2, pseudogene",-,GO:0019752//carboxylic acid metabolic process,GO:0030170//pyridoxal phosphate binding;GO:0016831//carboxy-lyase activity,"K01896//Butanoate metabolism;Metabolic pathways;Lipoic acid metabolism;K01580//Butanoate metabolism;GABAergic synapse;Type I diabetes mellitus;Biosynthesis of secondary metabolites;Taurine and hypotaurine metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways;beta-Alanine metabolism"
283971,3,0,0,0,0,0,0,0,2,1,14,0,"CLEC18C;C-type lectin domain family 18, member C",GO:0005576//extracellular region,-,GO:0030246//carbohydrate binding,-
283982,0,0,0,0,0,0,0,0,0,102,0,0,LINC00469;long intergenic non-protein coding RNA 469,-,-,-,-
283985,0,0,0,0,0,14,0,0,0,0,0,0,FADS6;fatty acid desaturase 6,GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process,GO:0016491//oxidoreductase activity,-
283987,0,0,0,0,4,22,23,0,17,0,0,0,HID1;HID1 domain containing,GO:0005737//cytoplasm;GO:0090498//extrinsic component of Golgi membrane;GO:0000138//Golgi trans cisterna;GO:0005881//cytoplasmic microtubule;GO:0070062//extracellular vesicular exosome;GO:0005797//Golgi medial cisterna;GO:0005794//Golgi apparatus,GO:0006886//intracellular protein transport;GO:0031001//response to brefeldin A,GO:0005515//protein binding,-
283989,1,199,65,147,232,0,0,716,0,0,603,0,TSEN54;TSEN54 tRNA splicing endonuclease subunit,GO:0005730//nucleolus,"GO:0006397//mRNA processing;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation",-,-
283991,88,0,0,14,19,0,0,6,0,0,5,0,UBALD2;UBA-like domain containing 2,-,-,-,-
283999,0,0,0,0,0,0,1,0,20,0,0,0,TMEM235;transmembrane protein 235,GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,GO:0005198//structural molecule activity,-
284,0,0,0,0,12,8,34,0,0,0,0,0,ANGPT1;angiopoietin 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0005902//microvillus,GO:0002040//sprouting angiogenesis;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0051897//positive regulation of protein kinase B signaling;GO:0001701//in utero embryonic development;GO:0050918//positive chemotaxis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048014//Tie signaling pathway;GO:0043116//negative regulation of vascular permeability;GO:0010595//positive regulation of endothelial cell migration;GO:0034394//protein localization to cell surface;GO:0014842//regulation of satellite cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0001936//regulation of endothelial cell proliferation;GO:0031589//cell-substrate adhesion;GO:0043524//negative regulation of neuron apoptotic process;GO:0030154//cell differentiation;GO:0030210//heparin biosynthetic process;GO:0045785//positive regulation of cell adhesion;GO:0050900//leukocyte migration;GO:0031398//positive regulation of protein ubiquitination;GO:0072012//glomerulus vasculature development;GO:0007162//negative regulation of cell adhesion;GO:0030097//hemopoiesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007596//blood coagulation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0002092//positive regulation of receptor internalization,GO:0030971//receptor tyrosine kinase binding,K05465//Rheumatoid arthritis
2840,0,0,0,0,0,12,33,1,20,0,0,299,GPR17;G protein-coupled receptor 17,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0070098//chemokine-mediated signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004950//chemokine receptor activity,-
284001,0,0,0,0,5,14,0,33,12,0,0,0,CCDC57;coiled-coil domain containing 57,-,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
284004,2,26,0,0,0,21,0,76,10,1,27,0,"HEXDC;hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0005975//carbohydrate metabolic process,GO:0004563//beta-N-acetylhexosaminidase activity,K14459//Other glycan degradation
284018,8,0,0,10,15,0,0,0,22,0,0,0,C17orf58;chromosome 17 open reading frame 58,-,-,-,-
284021,0,0,0,0,0,0,31,0,25,0,0,0,MILR1;mast cell immunoglobulin-like receptor 1,GO:0042629//mast cell granule;GO:0005887//integral component of plasma membrane,GO:0043303//mast cell degranulation;GO:0033004//negative regulation of mast cell activation,-,K11447//Transcriptional misregulation in cancer;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
284023,0,0,0,0,0,0,0,0,3,0,0,0,LOC284023;uncharacterized LOC284023,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
284029,0,0,0,5,0,0,1,0,6,0,16,0,LINC00324;long intergenic non-protein coding RNA 324,-,-,-,-
284040,0,0,0,0,0,0,0,0,19,0,0,0,CDRT4;CMT1A duplicated region transcript 4,-,-,-,-
284047,0,0,0,0,0,1,16,0,14,3,0,0,CCDC144B;coiled-coil domain containing 144B (pseudogene),-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K13645//Lysine degradation;K13755//Morphine addiction;Taste transduction;Purine metabolism;Olfactory transduction;Calcium signaling pathway
284058,66,0,56,0,5,8,0,67,0,0,0,0,KANSL1;KAT8 regulatory NSL complex subunit 1,GO:0005634//nucleus;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex,GO:0043982//histone H4-K8 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0006325//chromatin organization,GO:0005515//protein binding;GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific),-
284069,0,0,0,0,0,10,0,0,4,0,0,0,"FAM171A2;family with sequence similarity 171, member A2",GO:0016021//integral component of membrane,-,-,-
284071,0,0,0,0,23,7,1,0,49,0,19,0,C17orf104;chromosome 17 open reading frame 104,-,-,-,-
284076,1,0,0,0,0,0,0,1,32,0,5,496,"TTLL6;tubulin tyrosine ligase-like family, member 6",GO:0036064//ciliary basal body;GO:0005737//cytoplasm,GO:0001578//microtubule bundle formation;GO:0018095//protein polyglutamylation;GO:0051013//microtubule severing,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0015631//tubulin binding,"K00273//Metabolic pathways;Arginine and proline metabolism;D-Arginine and D-ornithine metabolism;Peroxisome;Glycine, serine and threonine metabolism;Penicillin and cephalosporin biosynthesis"
284083,0,0,0,0,0,34,0,0,16,0,13,0,C17orf47;chromosome 17 open reading frame 47,-,-,-,-
284085,0,0,1,0,0,15,0,0,0,0,2,0,KRT18P55;keratin 18 pseudogene 55,-,-,-,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
284086,0,0,0,0,0,7,0,0,0,0,0,0,NEK8;NIMA-related kinase 8,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0072372//primary cilium,GO:0035330//regulation of hippo signaling;GO:0009887//organ morphogenesis;GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
284098,0,0,0,0,1,0,0,0,11,0,0,0,"PIGW;phosphatidylinositol glycan anchor biosynthesis, class W",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K05283//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
284099,82,0,0,0,0,0,21,0,10,0,0,0,C17orf78;chromosome 17 open reading frame 78,GO:0016021//integral component of membrane,-,-,-
2841,0,0,0,0,0,15,41,0,19,0,0,0,GPR18;G protein-coupled receptor 18,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284106,0,119,169,233,1043,0,0,93,46,298,577,1,CISD3;CDGSH iron sulfur domain 3,GO:0005739//mitochondrion,-,"GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding",-
284110,0,0,0,0,0,0,0,80,54,0,0,0,GSDMA;gasdermin A,GO:0048471//perinuclear region of cytoplasm,GO:0006915//apoptotic process,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism
284111,60,0,22,0,0,15,0,33,54,0,3,75,"SLC13A5;solute carrier family 13 (sodium-dependent citrate transporter), member 5",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0015746//citrate transport;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0071422//succinate transmembrane transport;GO:0035674//tricarboxylic acid transmembrane transport,GO:0015141//succinate transmembrane transporter activity;GO:0015137//citrate transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity,-
284114,0,0,0,0,0,0,5,0,0,0,16,46,TMEM102;transmembrane protein 102,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0043234//protein complex,GO:2000406//positive regulation of T cell migration;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0045785//positive regulation of cell adhesion;GO:0007165//signal transduction;GO:0010820//positive regulation of T cell chemotaxis;GO:1901028//regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0034097//response to cytokine;GO:0006915//apoptotic process,GO:0005515//protein binding,-
284116,0,0,0,0,0,0,14,0,7,0,3,0,KRT42P;keratin 42 pseudogene,-,-,-,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
284119,0,23,0,19,105,0,21,0,34,0,71,0,PTRF;polymerase I and transcript release factor,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005901//caveola;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006360//transcription from RNA polymerase I promoter;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042134//rRNA primary transcript binding,K11447//Transcriptional misregulation in cancer
284129,0,0,0,0,0,42,23,0,71,0,3,0,"SLC26A11;solute carrier family 26 (anion exchanger), member 11",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane,GO:0008272//sulfate transport;GO:1902358//sulfate transmembrane transport,GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0015301//anion:anion antiporter activity,-
284131,126,0,0,5,14,0,0,1,74,0,0,0,ENDOV;endonuclease V,GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006281//DNA repair","GO:0003727//single-stranded RNA binding;GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0000287//magnesium ion binding;GO:0043566//structure-specific DNA binding;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters",K06478//Fc gamma R-mediated phagocytosis;T cell receptor signaling pathway;Primary immunodeficiency;Cell adhesion molecules (CAMs);K06236//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption;Amoebiasis;K03849//Metabolic pathways;N-Glycan biosynthesis
284161,0,0,0,0,0,0,10,0,50,0,7,0,GDPD1;glycerophosphodiester phosphodiesterase domain containing 1,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process,GO:0046872//metal ion binding;GO:0008889//glycerophosphodiester phosphodiesterase activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K01126//Sphingolipid metabolism;Glycerophospholipid metabolism;Other glycan degradation;K11447//Transcriptional misregulation in cancer
284184,0,0,0,0,7,0,0,0,0,0,0,0,C17orf89;chromosome 17 open reading frame 89,GO:0005739//mitochondrion,-,-,-
284185,0,0,0,0,0,0,24,0,39,0,0,0,LINC00482;long intergenic non-protein coding RNA 482,-,-,-,K11447//Transcriptional misregulation in cancer
284186,0,0,0,0,0,0,0,0,32,107,0,0,TMEM105;transmembrane protein 105,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
284194,0,0,0,0,0,0,0,0,25,0,3,0,"LGALS9B;lectin, galactoside-binding, soluble, 9B",-,-,GO:0030246//carbohydrate binding,-
2842,0,0,0,0,0,0,0,0,11,0,0,0,GPR19;G protein-coupled receptor 19,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284207,7,0,0,0,0,22,0,0,24,0,0,0,"METRNL;meteorin, glial cell differentiation regulator-like",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0050728//negative regulation of inflammatory response;GO:0090336//positive regulation of brown fat cell differentiation;GO:0009409//response to cold;GO:0050873//brown fat cell differentiation;GO:2000507//positive regulation of energy homeostasis;GO:0045444//fat cell differentiation;GO:0014850//response to muscle activity,GO:0005179//hormone activity,K00901//Glycerophospholipid metabolism;Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways
284217,68,0,0,0,0,35,38,77,46,110,10,0,"LAMA1;laminin, alpha 1",GO:0005911//cell-cell junction;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0005608//laminin-3 complex;GO:0005606//laminin-1 complex;GO:0005604//basement membrane;GO:0005615//extracellular space,GO:0045995//regulation of embryonic development;GO:0030155//regulation of cell adhesion;GO:0060445//branching involved in salivary gland morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0002011//morphogenesis of an epithelial sheet;GO:0007411//axon guidance;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0030198//extracellular matrix organization;GO:0061304//retinal blood vessel morphogenesis;GO:0030334//regulation of cell migration,GO:0005102//receptor binding;GO:0043208//glycosphingolipid binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent,K05637//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Small cell lung cancer;Dilated cardiomyopathy;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Toxoplasmosis;Viral myocarditis;Focal adhesion;Amoebiasis
284232,12,0,26,0,0,60,14,64,272,0,0,0,"ANKRD20A9P;ankyrin repeat domain 20 family, member A9, pseudogene",-,-,-,-
284252,2,1,0,0,6,0,0,0,20,0,0,0,KCTD1;potassium channel tetramerization domain containing 1,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0051260//protein homooligomerization;GO:0006351//transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0003714//transcription corepressor activity,-
284254,0,0,0,0,0,0,0,0,11,0,0,0,DYNAP;dynactin associated protein,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:1901625//cellular response to ergosterol;GO:0042981//regulation of apoptotic process;GO:0032148//activation of protein kinase B activity;GO:0008284//positive regulation of cell proliferation,GO:0005515//protein binding,-
284257,1,23,3,8,0,0,0,0,15,0,0,0,BOD1L2;biorientation of chromosomes in cell division 1-like 2,-,-,-,-
284266,0,0,0,0,0,0,18,0,0,0,0,0,SIGLEC15;sialic acid binding Ig-like lectin 15,GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0071402//cellular response to lipoprotein particle stimulus;GO:0045087//innate immune response;GO:2001204//regulation of osteoclast development;GO:0045124//regulation of bone resorption;GO:0032956//regulation of actin cytoskeleton organization,-,K06473//Hematopoietic cell lineage
284273,0,1,2,4,80,0,0,0,42,0,4,0,ZADH2;zinc binding alcohol dehydrogenase domain containing 2,GO:0005777//peroxisome;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity;GO:0008270//zinc ion binding,-
284274,0,0,0,0,0,0,0,0,28,0,0,0,SMIM21;small integral membrane protein 21,GO:0016021//integral component of membrane,-,-,-
284276,0,0,0,0,0,0,17,0,0,0,0,0,LINC00908;long intergenic non-protein coding RNA 908,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
284293,49,0,0,0,0,0,0,0,14,0,0,0,HMSD;histocompatibility (minor) serpin domain containing,GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
284297,70,0,0,0,0,14,44,37,65,0,6,1,SSC5D;scavenger receptor cysteine rich domain containing (5 domains),GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005622//intracellular,GO:2000483//negative regulation of interleukin-8 secretion;GO:0007275//multicellular organismal development;GO:0050829//defense response to Gram-negative bacterium;GO:0045087//innate immune response;GO:0042494//detection of bacterial lipoprotein;GO:0006898//receptor-mediated endocytosis;GO:0050830//defense response to Gram-positive bacterium,GO:0005044//scavenger receptor activity;GO:0043236//laminin binding;GO:0050840//extracellular matrix binding;GO:0001968//fibronectin binding,K13912//Salivary secretion
2843,0,0,0,0,0,0,0,0,26,0,7,0,GPR20;G protein-coupled receptor 20,GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284306,32,0,0,0,0,0,0,70,0,0,0,0,ZNF547;zinc finger protein 547,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284307,0,0,0,0,10,0,0,0,18,0,0,0,ZIK1;zinc finger protein interacting with K protein 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
284309,0,0,0,17,34,0,10,0,21,0,0,0,ZNF776;zinc finger protein 776,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284312,2,0,0,0,0,0,0,0,0,26,0,0,ZSCAN1;zinc finger and SCAN domain containing 1,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003713//transcription coactivator activity,-
284323,0,22,0,5,17,26,18,0,53,0,0,0,ZNF780A;zinc finger protein 780A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
284325,0,0,0,0,1,0,23,0,40,44,0,0,C19orf54;chromosome 19 open reading frame 54,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer
284338,0,371,53,95,251,15,44,104,25,0,622,1,PRR19;proline rich 19,-,-,-,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
284339,0,0,0,0,0,3,0,0,8,0,0,0,TMEM145;transmembrane protein 145,GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0019236//response to pheromone,-,-
284346,180,0,0,9,15,0,0,0,13,0,28,0,ZNF575;zinc finger protein 575,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284348,0,0,0,0,0,0,0,0,20,0,7,0,LYPD5;LY6/PLAUR domain containing 5,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,-,-,K03985//Complement and coagulation cascades
284349,0,0,0,7,17,0,0,0,0,0,0,0,ZNF283;zinc finger protein 283,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284352,270,28,0,0,9,30,0,70,30,1,9,0,"PPP1R37;protein phosphatase 1, regulatory subunit 37",-,GO:0010923//negative regulation of phosphatase activity,GO:0019902//phosphatase binding;GO:0005515//protein binding;GO:0004864//protein phosphatase inhibitor activity,K08727//Epithelial cell signaling in Helicobacter pylori infection;NOD-like receptor signaling pathway;Shigellosis;Pertussis
284353,0,1,59,19,0,0,0,0,41,0,0,0,"NKPD1;NTPase, KAP family P-loop domain containing 1",GO:0016021//integral component of membrane,-,-,K12460//Neurotrophin signaling pathway
284355,0,0,0,0,0,14,23,0,24,0,0,0,TPRX1;tetra-peptide repeat homeobox 1,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
284359,0,0,0,0,0,0,0,7,29,36,0,0,IZUMO1;izumo sperm-egg fusion 1,GO:0002080//acrosomal membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007342//fusion of sperm to egg plasma membrane;GO:0032504//multicellular organism reproduction;GO:0007155//cell adhesion;GO:0007338//single fertilization;GO:0035036//sperm-egg recognition,GO:0042803//protein homodimerization activity;GO:0005102//receptor binding,-
284361,0,27,1,11,16,37,93,0,31,0,81,0,EMC10;ER membrane protein complex subunit 10,GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane;GO:0005576//extracellular region,-,-,-
284366,80,0,0,0,0,0,11,0,0,0,0,174,KLK9;kallikrein-related peptidase 9,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
284367,0,0,0,0,0,0,0,3,0,0,0,0,"SIGLEC17P;sialic acid binding Ig-like lectin 17, pseudogene",-,-,-,K06473//Hematopoietic cell lineage
284370,0,19,0,30,177,0,5,0,14,0,0,0,ZNF615;zinc finger protein 615,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
284371,0,0,0,6,91,0,0,53,0,2,2,0,ZNF841;zinc finger protein 841,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
284379,1,0,0,0,0,0,0,0,14,0,12,0,"LOC284379;solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 pseudogene",-,-,-,-
284383,0,0,0,0,0,20,0,0,0,0,0,0,"OR2Z1;olfactory receptor, family 2, subfamily Z, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
284390,0,0,0,0,0,0,16,0,0,0,6,0,ZNF763;zinc finger protein 763,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
284391,0,63,0,0,14,0,39,0,32,0,0,0,ZNF844;zinc finger protein 844,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
2844,0,0,0,0,0,18,0,0,12,0,0,0,GPR21;G protein-coupled receptor 21,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0040018//positive regulation of multicellular organism growth;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0042593//glucose homeostasis,GO:0004930//G-protein coupled receptor activity,-
284403,0,0,26,0,0,0,21,0,118,0,0,1,WDR62;WD repeat domain 62,GO:0005730//nucleolus;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0021987//cerebral cortex development;GO:0022008//neurogenesis,-,K14555//Ribosome biogenesis in eukaryotes;K03362//Oocyte meiosis;Wnt signaling pathway;Hedgehog signaling pathway;Shigellosis;Ubiquitin mediated proteolysis;Circadian rhythm - mammal
284406,0,0,0,0,48,13,17,0,0,0,0,0,ZFP82;ZFP82 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284412,0,0,0,0,0,0,3,0,4,1,4,4,LOC284412;uncharacterized LOC284412,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
284415,0,0,0,0,0,18,0,0,0,0,0,0,VSTM1;V-set and transmembrane domain containing 1,GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0002376//immune system process,GO:0005125//cytokine activity,K14377//Osteoclast differentiation;K06512//B cell receptor signaling pathway;Osteoclast differentiation;K06513//Phagosome;Staphylococcus aureus infection
284417,0,0,0,0,0,0,24,0,3,1,0,263,TMEM150B;transmembrane protein 150B,GO:0016021//integral component of membrane,-,-,-
284418,0,0,5,0,0,12,15,38,20,0,8,0,"FAM71E2;family with sequence similarity 71, member E2",-,-,-,-
284422,2,0,0,0,0,0,0,0,22,0,0,0,SMIM24;small integral membrane protein 24,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
284428,0,0,0,0,0,0,0,2,0,0,0,1,MBD3L5;methyl-CpG binding domain protein 3-like 5,-,-,-,-
284434,6,276,59,76,201,13,72,1,34,0,7,318,NWD1;NACHT and WD repeat domain containing 1,-,-,GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer
284439,93,0,0,0,0,0,28,0,14,0,3,0,"SLC25A42;solute carrier family 25, member 42",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0015867//ATP transport;GO:0080121//AMP transport;GO:0015866//ADP transport;GO:0035349//coenzyme A transmembrane transport;GO:0008152//metabolic process,GO:0015228//coenzyme A transmembrane transporter activity;GO:0043262//adenosine-diphosphatase activity;GO:0080122//AMP transmembrane transporter activity;GO:0005347//ATP transmembrane transporter activity;GO:0015217//ADP transmembrane transporter activity,-
284440,0,0,0,0,0,0,29,0,18,0,0,0,LINC00663;long intergenic non-protein coding RNA 663,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
284443,0,0,0,14,21,16,15,2,21,0,0,0,ZNF493;zinc finger protein 493,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
284451,2,0,0,0,0,13,0,0,9,0,0,0,ODF3L2;outer dense fiber of sperm tails 3-like 2,GO:0005881//cytoplasmic microtubule,-,-,K13909//Salivary secretion
284459,0,41,0,0,44,23,3,0,13,0,0,0,"HKR1;HKR1, GLI-Kruppel zinc finger family member",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
284467,0,0,0,0,0,0,0,0,14,0,0,212,"FAM19A3;family with sequence similarity 19 (chemokine (C-C motif)-like), member A3",GO:0005576//extracellular region,-,-,-
284486,0,19,1,50,48,12,0,164,30,0,25,0,THEM5;thioesterase superfamily member 5,GO:0005759//mitochondrial matrix,GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0006631//fatty acid metabolic process;GO:0035965//cardiolipin acyl-chain remodeling,GO:0016290//palmitoyl-CoA hydrolase activity,-
284498,0,351,365,325,476,15,98,1154,276,118,1468,479,C1orf167;chromosome 1 open reading frame 167,-,-,-,-
2845,0,0,0,0,0,15,0,0,0,0,0,0,GPR22;G protein-coupled receptor 22,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284521,0,24,0,9,0,0,0,0,28,0,0,0,"OR2L13;olfactory receptor, family 2, subfamily L, member 13",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0005515//protein binding;GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
284525,0,0,0,0,0,26,29,0,62,287,0,21,"SLC9C2;solute carrier family 9, member C2 (putative)",GO:0016021//integral component of membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0006814//sodium ion transport,GO:0015299//solute:proton antiporter activity,-
284541,0,0,0,0,0,1,12,0,10,266,12,0,"CYP4A22;cytochrome P450, family 4, subfamily A, polypeptide 22",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process,GO:0020037//heme binding;GO:0052869//arachidonic acid omega-hydroxylase activity;GO:0018685//alkane 1-monooxygenase activity;GO:0005506//iron ion binding,K07425//Arachidonic acid metabolism;PPAR signaling pathway;Metabolic pathways;Vascular smooth muscle contraction;Fatty acid metabolism;Retinol metabolism
284551,0,0,0,0,0,10,0,0,26,0,0,0,LINC01226;long intergenic non-protein coding RNA 1226,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
284565,69,63,1,10,7,1,22,0,29,0,0,0,"NBPF15;neuroblastoma breakpoint family, member 15",GO:0005737//cytoplasm,-,-,K05759//Shigellosis;Regulation of actin cytoskeleton;Salmonella infection
284581,0,0,0,0,0,28,0,15,4,0,0,0,LOC284581;uncharacterized LOC284581,GO:0016021//integral component of membrane,-,-,"K00854//Pyrimidine metabolism;Alanine, aspartate and glutamate metabolism;Pentose and glucuronate interconversions;Metabolic pathways"
284593,0,0,0,0,0,0,0,0,19,0,0,0,"FAM41C;family with sequence similarity 41, member C",-,-,-,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome
284611,0,54,0,21,55,25,0,0,30,2,0,0,"FAM102B;family with sequence similarity 102, member B",-,-,-,-
284612,0,0,0,0,0,31,0,0,50,0,0,0,SYPL2;synaptophysin-like 2,GO:0030285//integral component of synaptic vesicle membrane,GO:0021762//substantia nigra development;GO:0006874//cellular calcium ion homeostasis;GO:0006810//transport,GO:0005215//transporter activity,-
284613,0,0,0,0,13,34,0,0,16,0,3,0,"CYB561D1;cytochrome b561 family, member D1",GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding,-
284615,0,31,0,0,0,14,0,0,15,0,0,0,ANKRD34A;ankyrin repeat domain 34A,GO:0005737//cytoplasm,-,-,-
284618,0,0,35,26,16,0,0,0,24,0,60,0,RUSC1-AS1;RUSC1 antisense RNA 1,-,-,-,K00787//HTLV-I infection;Metabolic pathways;Terpenoid backbone biosynthesis;Influenza A;Biosynthesis of secondary metabolites
284648,0,0,0,0,0,0,0,0,16,0,0,0,LOC284648;uncharacterized LOC284648,-,-,-,-
284649,0,0,0,9,0,0,0,0,6,0,27,0,SMG7-AS1;SMG7 antisense RNA 1,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
284654,0,0,0,0,0,13,105,26,18,0,0,0,RSPO1;R-spondin 1,GO:0005615//extracellular space;GO:0005634//nucleus,GO:0010468//regulation of gene expression;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0002090//regulation of receptor internalization;GO:2000254//regulation of male germ cell proliferation;GO:0007140//male meiosis,GO:0005515//protein binding;GO:0008201//heparin binding;GO:0001664//G-protein coupled receptor binding;GO:0005102//receptor binding,-
284656,79,61,1,0,1,27,16,12,62,94,21,0,EPHA10;EPH receptor A10,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048013//ephrin receptor signaling pathway,GO:0005515//protein binding;GO:0005005//transmembrane-ephrin receptor activity;GO:0005003//ephrin receptor activity;GO:0005524//ATP binding,-
284677,0,0,0,0,0,0,0,0,19,0,0,18,C1orf204;chromosome 1 open reading frame 204,-,-,-,-
284695,0,29,0,4,20,16,23,0,21,0,0,163,ZNF326;zinc finger protein 326,GO:0016363//nuclear matrix;GO:0005681//spliceosomal complex;GO:0044609//DBIRD complex,"GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0032784//regulation of DNA-templated transcription, elongation",GO:0000993//RNA polymerase II core binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
284697,0,0,0,0,0,0,0,0,4,1,0,474,BTBD8;BTB (POZ) domain containing 8,GO:0005634//nucleus,-,-,-
2847,0,0,0,0,0,0,0,32,17,0,0,0,MCHR1;melanin-concentrating hormone receptor 1,GO:0005886//plasma membrane;GO:0031513//nonmotile primary cilium;GO:0005887//integral component of plasma membrane,GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006091//generation of precursor metabolites and energy;GO:0051928//positive regulation of calcium ion transport;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior,GO:0030273//melanin-concentrating hormone receptor activity;GO:0008188//neuropeptide receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0008022//protein C-terminus binding;GO:0042562//hormone binding,K04320//Neuroactive ligand-receptor interaction
284716,0,24,1,13,22,13,58,3,73,82,0,0,RIMKLA;ribosomal modification protein rimK-like family member A,GO:0005737//cytoplasm,GO:0006464//cellular protein modification process,GO:0046872//metal ion binding;GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity;GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
284723,90,0,0,0,0,21,0,0,11,138,0,0,"SLC25A34;solute carrier family 25, member 34",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006810//transport,-,-
284729,3,0,17,0,0,34,24,0,80,106,10,0,ESPNP;espin pseudogene,-,-,-,-
284739,93,0,0,0,0,18,0,0,50,98,12,382,LINC00176;long intergenic non-protein coding RNA 176,-,-,-,-
284756,0,0,0,0,0,0,0,0,4,0,0,0,C20orf197;chromosome 20 open reading frame 197,-,-,-,-
284759,0,0,0,0,0,5,0,0,16,0,13,0,SIRPB2;signal-regulatory protein beta 2,GO:0016021//integral component of membrane,-,-,K06551//Osteoclast differentiation
2848,0,0,0,0,0,23,0,0,0,0,0,1,GPR25;G protein-coupled receptor 25,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284800,0,0,0,0,0,0,4,3,18,0,0,0,"FAM182A;family with sequence similarity 182, member A",-,-,-,-
284802,14,0,0,0,0,11,15,0,13,0,0,0,"FRG1B;FSHD region gene 1 family, member B",-,-,-,-
284805,0,0,0,0,0,0,59,0,0,0,19,0,C20orf203;chromosome 20 open reading frame 203,GO:0005737//cytoplasm,-,-,-
284827,0,0,0,0,0,0,0,0,14,0,0,0,KRTAP13-4;keratin associated protein 13-4,GO:0005882//intermediate filament,-,-,-
284836,90,0,0,0,0,18,25,0,41,0,0,1,LINC00319;long intergenic non-protein coding RNA 319,-,-,-,-
284837,0,0,0,10,1,0,15,1,23,8,3,0,LOC284837;uncharacterized LOC284837,-,-,-,-
284865,0,0,0,0,0,23,47,33,22,0,0,193,LOC284865;uncharacterized LOC284865,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
284889,129,5502,2240,2113,6018,0,162,2890,321,364,8354,526,LOC284889;uncharacterized LOC284889,-,-,-,K07253//Tyrosine metabolism;Phenylalanine metabolism
2849,0,0,0,0,0,18,74,53,58,117,0,0,GPR26;G protein-coupled receptor 26,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
284900,93,101,38,11,27,13,0,0,26,0,33,0,TTC28-AS1;TTC28 antisense RNA 1,-,-,-,K11433//Lysine degradation
284904,0,0,0,0,0,0,0,0,54,0,0,0,SEC14L4;SEC14-like 4 (S. cerevisiae),GO:0005622//intracellular;GO:0016021//integral component of membrane,GO:0006810//transport,GO:0008289//lipid binding;GO:0005215//transporter activity,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
284942,36,0,0,2,0,0,44,0,0,0,8,0,RPL23AP82;ribosomal protein L23a pseudogene 82,-,-,-,K02893//Ribosome
284992,0,0,0,0,0,0,22,0,27,270,0,0,CCDC150;coiled-coil domain containing 150,-,-,-,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
284996,0,0,0,0,0,1,0,0,0,0,6,0,RNF149;ring finger protein 149,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0043409//negative regulation of MAPK cascade;GO:0035690//cellular response to drug;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
285,0,17,24,38,47,0,0,154,46,0,52,0,ANGPT2;angiopoietin 2,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0042995//cell projection,GO:0014823//response to activity;GO:0045766//positive regulation of angiogenesis;GO:0009749//response to glucose;GO:0007281//germ cell development;GO:0031100//organ regeneration;GO:0001525//angiogenesis;GO:0048014//Tie signaling pathway;GO:0001666//response to hypoxia;GO:0009612//response to mechanical stimulus;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0072012//glomerulus vasculature development;GO:0060135//maternal process involved in female pregnancy;GO:0009314//response to radiation;GO:0007596//blood coagulation;GO:0071363//cellular response to growth factor stimulus;GO:0010812//negative regulation of cell-substrate adhesion;GO:0016525//negative regulation of angiogenesis;GO:0014070//response to organic cyclic compound;GO:0050928//negative regulation of positive chemotaxis;GO:0050900//leukocyte migration;GO:0007165//signal transduction,GO:0030971//receptor tyrosine kinase binding;GO:0005102//receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
2850,2,23,9,14,30,0,0,46,11,62,7,0,GPR27;G protein-coupled receptor 27,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
285016,0,0,45,0,15,16,0,0,17,0,0,0,"FAM150B;family with sequence similarity 150, member B",GO:0005576//extracellular region,-,-,-
285025,116,0,0,0,0,30,26,0,50,0,3,0,CCDC141;coiled-coil domain containing 141,-,-,GO:0005515//protein binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
285051,0,0,0,0,0,2,17,0,24,0,0,0,C2orf61;chromosome 2 open reading frame 61,-,-,-,-
285093,0,0,0,0,0,13,0,0,10,0,0,0,RTP5;receptor (chemosensory) transporter protein 5 (putative),GO:0016021//integral component of membrane,-,-,-
28511,0,33,0,22,3,27,0,103,0,0,20,0,NKIRAS2;NFKB inhibitor interacting Ras-like 2,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling,GO:0005525//GTP binding;GO:0003924//GTPase activity,K11447//Transcriptional misregulation in cancer;K07208//Insulin signaling pathway;mTOR signaling pathway
285116,205,0,0,18,0,0,0,0,44,0,6,1,AHCTF1P1;AT hook containing transcription factor 1 pseudogene 1,-,-,-,K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Gastric acid secretion;Calcium signaling pathway;Focal adhesion
28512,0,0,0,20,0,0,0,0,0,0,0,0,NKIRAS1;NFKB inhibitor interacting Ras-like 1,GO:0005737//cytoplasm;GO:0016020//membrane,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling,GO:0003924//GTPase activity;GO:0005525//GTP binding,K07898//Salmonella infection;Phagosome;Amoebiasis
285126,96,0,0,0,0,0,0,0,16,0,2,0,"DNAJC5G;DnaJ (Hsp40) homolog, subfamily C, member 5 gamma",GO:0016020//membrane,-,-,K09525//Protein processing in endoplasmic reticulum
28513,107,0,0,0,0,0,44,30,82,77,0,1,"CDH19;cadherin 19, type 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
28514,29,0,0,0,0,13,0,54,0,2,3,0,DLL1;delta-like 1 (Drosophila),GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle,GO:0072070//loop of Henle development;GO:0045747//positive regulation of Notch signaling pathway;GO:0070986//left/right axis specification;GO:0030097//hemopoiesis;GO:0001757//somite specification;GO:0001709//cell fate determination;GO:0072014//proximal tubule development;GO:0030155//regulation of cell adhesion;GO:0048839//inner ear development;GO:0007368//determination of left/right symmetry;GO:0007219//Notch signaling pathway;GO:0007386//compartment pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045608//negative regulation of auditory receptor cell differentiation;GO:0030154//cell differentiation;GO:0007220//Notch receptor processing;GO:0097150//neuronal stem cell maintenance;GO:0001947//heart looping;GO:0032693//negative regulation of interleukin-10 production;GO:0007267//cell-cell signaling;GO:0045638//negative regulation of myeloid cell differentiation,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005112//Notch binding,K06051//Notch signaling pathway
285141,0,0,0,0,11,0,0,0,27,0,0,0,ERICH2;glutamate-rich 2,-,-,-,-
285148,0,24,0,9,27,0,0,0,0,0,11,0,IAH1;isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae),GO:0070062//extracellular vesicular exosome,GO:0016042//lipid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds",-
285172,56,98,2,21,72,36,0,0,51,77,0,0,"FAM126B;family with sequence similarity 126, member B",GO:0005622//intracellular,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
285175,2,43,1,27,73,44,0,45,80,140,14,304,UNC80;unc-80 homolog (C. elegans),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,-,K00255//Fatty acid metabolism;PPAR signaling pathway;Metabolic pathways
285180,0,0,0,0,0,42,30,0,11,5,0,0,RUFY4;RUN and FYVE domain containing 4,-,-,GO:0046872//metal ion binding,K05050//Cytokine-cytokine receptor interaction;Endocytosis;Chemokine signaling pathway;Epithelial cell signaling in Helicobacter pylori infection
285189,0,0,0,0,0,0,0,4,15,0,0,0,PLGLA;plasminogen-like A (pseudogene),GO:0005576//extracellular region,-,-,K01315//Influenza A;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Staphylococcus aureus infection
285190,0,0,0,0,0,0,45,0,1,0,0,0,RGPD4;RANBP2-like and GRIP domain containing 4,-,GO:0000042//protein targeting to Golgi,-,K12172//RNA transport
285193,0,0,1,4,25,10,0,0,6,0,48,0,DUSP28;dual specificity phosphatase 28,-,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0007254//JNK cascade,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,-
285195,79,0,0,0,2,10,12,0,21,0,21,0,"SLC9A9;solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9",GO:0016021//integral component of membrane;GO:0055037//recycling endosome;GO:0031902//late endosome membrane,GO:0006811//ion transport;GO:1902600//hydrogen ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0006885//regulation of pH;GO:0055085//transmembrane transport,GO:0005515//protein binding;GO:0015385//sodium:proton antiporter activity,-
2852,125,0,0,0,0,0,0,0,58,0,4,0,GPER1;G protein-coupled estrogen receptor 1,GO:0030659//cytoplasmic vesicle membrane;GO:0005783//endoplasmic reticulum;GO:0032591//dendritic spine membrane;GO:0043198//dendritic shaft;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network;GO:0044327//dendritic spine head;GO:0005622//intracellular;GO:0005789//endoplasmic reticulum membrane;GO:0055037//recycling endosome;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0097481//neuronal postsynaptic density;GO:0000139//Golgi membrane;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0031966//mitochondrial membrane;GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0048786//presynaptic active zone;GO:0045095//keratin filament;GO:0005634//nucleus,GO:0051053//negative regulation of DNA metabolic process;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071375//cellular response to peptide hormone stimulus;GO:0051055//negative regulation of lipid biosynthetic process;GO:0045909//positive regulation of vasodilation;GO:0030264//nuclear fragmentation involved in apoptotic nuclear change;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050728//negative regulation of inflammatory response;GO:0043065//positive regulation of apoptotic process;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0071392//cellular response to estradiol stimulus;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0071157//negative regulation of cell cycle arrest;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0045599//negative regulation of fat cell differentiation;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002695//negative regulation of leukocyte activation;GO:0030335//positive regulation of cell migration;GO:0032024//positive regulation of insulin secretion;GO:0001956//positive regulation of neurotransmitter secretion;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0071356//cellular response to tumor necrosis factor;GO:0050769//positive regulation of neurogenesis;GO:0043401//steroid hormone mediated signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0071333//cellular response to glucose stimulus;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0030263//apoptotic chromosome condensation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0031959//mineralocorticoid receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0010629//negative regulation of gene expression;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0007049//cell cycle;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0019228//neuronal action potential;GO:0051480//cytosolic calcium ion homeostasis;GO:0071389//cellular response to mineralocorticoid stimulus;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway,GO:0030284//estrogen receptor activity;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0005496//steroid binding;GO:0017082//mineralocorticoid receptor activity;GO:0003682//chromatin binding,-
285203,0,0,0,17,41,15,15,2,32,123,22,0,EOGT;EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase,GO:0005788//endoplasmic reticulum lumen,GO:0006493//protein O-linked glycosylation,GO:0016262//protein N-acetylglucosaminyltransferase activity,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
285220,90,0,0,0,0,26,10,0,106,0,0,0,EPHA6;EPH receptor A6,GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048013//ephrin receptor signaling pathway,GO:0005003//ephrin receptor activity;GO:0005524//ATP binding,K05107//Axon guidance
285231,0,0,0,0,0,0,0,0,6,0,7,0,FBXW12;F-box and WD repeat domain containing 12,-,-,-,-
285237,0,52,0,15,46,0,0,0,23,153,0,0,C3orf38;chromosome 3 open reading frame 38,-,GO:0006915//apoptotic process,-,-
285242,132,0,0,0,0,4,20,0,2,0,0,0,"HTR3E;5-hydroxytryptamine (serotonin) receptor 3E, ionotropic",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005230//extracellular ligand-gated ion channel activity,K04819//Serotonergic synapse
285266,0,0,0,0,12,0,0,65,0,0,0,0,ENTPD3-AS1;ENTPD3 antisense RNA 1,-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
285267,0,0,0,0,13,0,27,0,11,0,0,0,ZNF619;zinc finger protein 619,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
285268,75,0,0,10,32,6,1,9,43,0,1,330,ZNF621;zinc finger protein 621,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
285282,0,12,1,16,39,1,43,0,70,0,0,0,"RABL3;RAB, member of RAS oncogene family-like 3",-,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
2853,0,0,0,0,0,0,0,17,0,0,2,0,GPR31;G protein-coupled receptor 31,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
285311,0,0,0,0,0,0,0,0,43,0,0,0,C3orf56;chromosome 3 open reading frame 56,-,-,-,-
285313,0,0,0,0,0,63,0,0,95,0,28,0,"IGSF10;immunoglobulin superfamily, member 10",GO:0005576//extracellular region,GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0001503//ossification,-,K06255//ECM-receptor interaction
285315,0,0,0,0,0,0,0,0,7,0,0,0,C3orf33;chromosome 3 open reading frame 33,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0008152//metabolic process,"GO:0003676//nucleic acid binding;GO:0016788//hydrolase activity, acting on ester bonds",K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
285331,0,0,0,13,34,16,11,31,18,0,0,0,CCDC66;coiled-coil domain containing 66,-,GO:0046548//retinal rod cell development;GO:0060060//post-embryonic retina morphogenesis in camera-type eye,-,-
285335,1,0,0,0,0,57,0,0,57,0,0,1,"SLC9C1;solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1",GO:0016021//integral component of membrane;GO:0031514//motile cilium;GO:0005886//plasma membrane,GO:0006814//sodium ion transport;GO:0030154//cell differentiation;GO:1902600//hydrogen ion transmembrane transport;GO:0030317//sperm motility;GO:0007275//multicellular organismal development;GO:0055085//transmembrane transport;GO:0007283//spermatogenesis;GO:0034220//ion transmembrane transport,GO:0015299//solute:proton antiporter activity,-
285343,0,32,0,15,47,0,118,0,44,0,0,0,"TCAIM;T cell activation inhibitor, mitochondrial",GO:0005739//mitochondrion,-,-,-
285346,0,0,40,17,0,0,0,0,39,0,0,0,ZNF852;zinc finger protein 852,-,-,GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
285349,0,0,0,15,0,0,11,0,9,0,0,0,ZNF660;zinc finger protein 660,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
285362,0,0,0,0,9,0,0,0,35,0,0,0,SUMF1;sulfatase modifying factor 1,GO:0005788//endoplasmic reticulum lumen,GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process;GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0016491//oxidoreductase activity,K13444//Lysosome
285367,0,0,0,0,0,0,0,2,28,0,0,0,RPUSD3;RNA pseudouridylate synthase domain containing 3,-,GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0044822//poly(A) RNA binding,-
285368,135,0,0,6,4,41,43,35,8,0,77,0,PRRT3;proline-rich transmembrane protein 3,GO:0016021//integral component of membrane,-,-,K03260//RNA transport;Viral myocarditis
285381,0,0,0,6,1,0,0,0,0,0,0,0,DPH3;diphthamide biosynthesis 3,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0050709//negative regulation of protein secretion;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine;GO:0051099//positive regulation of binding,GO:0005515//protein binding;GO:0046872//metal ion binding,-
285382,0,0,0,0,0,0,15,0,21,0,0,0,C3orf70;chromosome 3 open reading frame 70,-,-,-,"K07514//Peroxisome;Tryptophan metabolism;PPAR signaling pathway;Butanoate metabolism;Fatty acid metabolism;Lysine degradation;Propanoate metabolism;Metabolic pathways;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways"
2854,0,0,0,0,0,0,10,0,0,0,0,0,GPR32;G protein-coupled receptor 32,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,K04173//Staphylococcus aureus infection;Neuroactive ligand-receptor interaction
285407,86,107,31,10,65,16,6,0,54,0,97,0,"ALG1L9P;asparagine-linked glycosylation 1-like 9, pseudogene",-,-,-,K11447//Transcriptional misregulation in cancer;K03842//N-Glycan biosynthesis;Metabolic pathways;Various types of N-glycan biosynthesis;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
285429,0,0,0,0,0,10,0,15,0,0,0,0,DCAF4L1;DDB1 and CUL4 associated factor 4-like 1,-,-,-,-
285440,77,0,0,0,40,0,40,0,13,0,5,0,"CYP4V2;cytochrome P450, family 4, subfamily V, polypeptide 2",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0010430//fatty acid omega-oxidation,"GO:0004497//monooxygenase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",-
285441,0,0,0,0,0,0,0,0,0,0,3,0,F11-AS1;F11 antisense RNA 1,-,-,-,K01323//Complement and coagulation cascades
285463,73,1775,857,1430,2801,0,74,4014,618,205,5104,5,CTBP1-AS;CTBP1 antisense RNA,-,-,-,K04496//Pathways in cancer;Wnt signaling pathway;Chronic myeloid leukemia;Notch signaling pathway
285464,107,0,0,0,0,0,1,0,9,0,1,0,CRIPAK;cysteine-rich PAK1 inhibitor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,GO:0051493//regulation of cytoskeleton organization;GO:0006469//negative regulation of protein kinase activity;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0043627//response to estrogen,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
285489,0,0,0,0,11,13,0,0,39,0,0,0,DOK7;docking protein 7,GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction,GO:0007528//neuromuscular junction development;GO:0043113//receptor clustering;GO:0061098//positive regulation of protein tyrosine kinase activity,GO:0035091//phosphatidylinositol binding;GO:0019901//protein kinase binding;GO:0005158//insulin receptor binding,-
285492,0,0,0,0,0,11,0,0,34,0,0,0,LINC00955;long intergenic non-protein coding RNA 955,-,-,-,-
285498,0,0,0,0,0,8,0,0,82,0,0,0,RNF212;ring finger protein 212,GO:0000795//synaptonemal complex,GO:0007131//reciprocal meiotic recombination;GO:0006311//meiotic gene conversion;GO:0051026//chiasma assembly;GO:0016925//protein sumoylation,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
285513,0,1,0,0,0,0,31,0,42,0,0,0,GPRIN3;GPRIN family member 3,-,-,-,-
285525,0,0,0,0,0,0,0,0,17,0,0,0,"YIPF7;Yip1 domain family, member 7",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,K00102//Pyruvate metabolism;K12603//RNA degradation;K01887//Aminoacyl-tRNA biosynthesis
285527,0,0,0,3,53,61,72,55,42,0,29,0,FRYL;FRY-like,-,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
285533,74,0,0,0,0,18,37,153,34,0,0,0,RNF175;ring finger protein 175,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
285547,0,0,0,0,0,0,0,0,3,0,0,0,LINC01097;long intergenic non-protein coding RNA 1097,-,-,-,-
285550,0,24,0,0,13,34,0,0,77,0,0,0,"FAM200B;family with sequence similarity 200, member B",-,-,GO:0003676//nucleic acid binding,K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K06103//Tight junction
285555,0,0,0,0,0,0,23,0,5,0,6,0,STPG2;sperm-tail PG-rich repeat containing 2,-,-,-,-
285590,162,0,0,16,1,16,29,0,43,0,10,0,SH3PXD2B;SH3 and PX domains 2B,GO:0002102//podosome;GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0030054//cell junction,GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly;GO:0071800//podosome assembly;GO:0007507//heart development;GO:0045600//positive regulation of fat cell differentiation;GO:0001654//eye development;GO:0072657//protein localization to membrane;GO:0001501//skeletal system development;GO:0060348//bone development;GO:0060612//adipose tissue development;GO:0006801//superoxide metabolic process,"GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0042169//SH2 domain binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding",K08011//Osteoclast differentiation;Leishmaniasis;Chemokine signaling pathway;Phagosome;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration
285596,0,0,0,0,13,1,0,0,11,0,0,8,"FAM153A;family with sequence similarity 153, member A",-,-,-,-
285598,0,0,0,0,0,0,30,0,28,0,14,0,ARL10;ADP-ribosylation factor-like 10,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
285600,205,0,29,0,2,11,22,61,13,1,0,4,KIAA0825;KIAA0825,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
285601,0,0,0,0,4,0,0,0,0,0,12,0,GPR150;G protein-coupled receptor 150,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
285605,0,25,0,0,33,12,0,0,47,0,0,0,DTWD2;DTW domain containing 2,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
285613,0,33,0,22,26,0,0,108,17,0,268,1,RELL2;RELT-like 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005604//basement membrane,GO:0010811//positive regulation of cell-substrate adhesion,GO:0005518//collagen binding,K05156//Cytokine-cytokine receptor interaction
285622,0,0,0,0,13,0,34,0,51,0,0,0,"NBPF22P;neuroblastoma breakpoint family, member 22, pseudogene",-,-,-,-
285636,0,45,1,28,94,0,0,0,32,0,0,0,C5orf51;chromosome 5 open reading frame 51,-,-,-,-
285641,0,0,0,0,0,24,13,0,35,0,0,0,"SLC36A3;solute carrier family 36, member 3",GO:0016021//integral component of membrane,-,-,K14209//Protein digestion and absorption
285643,0,0,0,0,0,5,1,0,42,0,0,0,KIF4B;kinesin family member 4B,GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0005874//microtubule;GO:0005634//nucleus,GO:0007411//axon guidance;GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement,GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity;GO:0003677//DNA binding,-
285659,49,0,0,0,0,0,0,0,0,0,0,0,"OR2V2;olfactory receptor, family 2, subfamily V, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
285668,0,0,0,0,0,27,0,67,48,0,0,0,C5orf64;chromosome 5 open reading frame 64,GO:0005576//extracellular region,-,-,K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;Metabolic pathways;beta-Alanine metabolism;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
285671,0,0,0,0,14,0,20,0,24,0,0,0,RNF180;ring finger protein 180,GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope,GO:0050790//regulation of catalytic activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0030534//adult behavior;GO:0042428//serotonin metabolic process;GO:0000209//protein polyubiquitination;GO:0042415//norepinephrine metabolic process,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0031624//ubiquitin conjugating enzyme binding,-
285672,71,23,0,35,60,11,35,11,53,0,0,0,SREK1IP1;SREK1-interacting protein 1,-,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
285676,0,0,0,0,0,0,8,0,7,0,0,0,ZNF454;zinc finger protein 454,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
285679,84,0,0,0,0,10,0,0,11,0,0,0,C5orf60;chromosome 5 open reading frame 60,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
285696,0,0,0,0,0,0,0,0,14,0,0,0,LOC285696;uncharacterized LOC285696,-,-,-,K11447//Transcriptional misregulation in cancer
2857,0,0,0,0,0,0,0,0,17,0,0,0,GPR34;G protein-coupled receptor 34,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
285704,0,0,8,15,18,0,48,7,36,0,0,0,RGMB;repulsive guidance molecule family member b,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane,"GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0030509//BMP signaling pathway;GO:0007155//cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated",GO:0042802//identical protein binding,-
285753,13,0,0,0,3,0,0,0,7,65,4,0,CEP57L1;centrosomal protein 57kDa-like 1,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005874//microtubule,GO:0034453//microtubule anchoring,GO:0042802//identical protein binding;GO:0008017//microtubule binding;GO:0043015//gamma-tubulin binding,-
285755,0,184,209,87,104,0,19,1308,344,152,186,506,PPIL6;peptidylprolyl isomerase (cyclophilin)-like 6,-,GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
285761,0,171,198,259,387,0,29,0,12,0,272,0,"DCBLD1;discoidin, CUB and LCCL domain containing 1",GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,K03902//Complement and coagulation cascades
285782,0,0,0,1,0,28,3,0,52,0,0,0,CAGE1;cancer antigen 1,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K12478//Phagosome;Endocytosis;Tuberculosis
285800,0,51,0,0,0,0,16,0,21,0,31,0,PRR18;proline rich 18,-,-,-,-
285834,0,0,0,0,0,3,0,0,21,0,0,0,HCG22;HLA complex group 22,GO:0005576//extracellular region,-,-,K12968//Cytosolic DNA-sensing pathway;Influenza A;Measles
285848,0,0,0,0,0,0,0,0,9,0,0,0,PNPLA1;patatin-like phospholipase domain containing 1,GO:0005737//cytoplasm,GO:0016042//lipid catabolic process,GO:0016787//hydrolase activity,K11157//Retinol metabolism;K13534//Glycerolipid metabolism;Metabolic pathways
285852,49,0,0,0,0,16,0,1,0,0,0,0,TREML4;triggering receptor expressed on myeloid cells-like 4,GO:0005576//extracellular region,-,-,K06742//Natural killer cell mediated cytotoxicity
285855,0,46,1,32,47,0,0,0,0,0,0,0,RPL7L1;ribosomal protein L7-like 1,GO:0005840//ribosome,-,GO:0044822//poly(A) RNA binding,K02937//Ribosome
285877,0,0,0,0,0,18,18,0,0,0,0,0,POM121L12;POM121 transmembrane nucleoporin-like 12,-,-,-,K14316//RNA transport
285888,0,0,0,0,0,0,0,0,17,0,0,0,CNPY1;canopy FGF signaling regulator 1,-,-,-,K01647//Citrate cycle (TCA cycle);Metabolic pathways;ABC transporters;Pyruvate metabolism;Glyoxylate and dicarboxylate metabolism;Microbial metabolism in diverse environments;Methane metabolism;Biosynthesis of secondary metabolites
2859,57,0,0,0,0,0,0,38,52,0,0,0,GPR35;G protein-coupled receptor 35,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,K04276//Neuroactive ligand-receptor interaction
285908,0,0,0,0,0,0,0,0,17,0,3,0,LINC00174;long intergenic non-protein coding RNA 174,-,-,-,-
285941,0,0,0,0,8,0,0,0,0,95,10,0,C7orf71;chromosome 7 open reading frame 71,-,-,-,-
285943,0,0,0,0,16,0,0,0,0,15,12,0,HOXA-AS2;HOXA cluster antisense RNA 2,-,-,-,-
285955,1,0,1,8,12,0,0,91,21,1,41,0,SPDYE1;speedy/RINGO cell cycle regulator family member E1,-,-,-,K08694//Oocyte meiosis;Progesterone-mediated oocyte maturation
285961,0,0,0,0,0,0,0,0,11,0,0,0,SEPT7P9;septin 7 pseudogene 9,-,-,-,K04557//Parkinson's disease
285966,0,0,0,0,2,1,23,1,0,51,0,0,"FAM115C;family with sequence similarity 115, member C",-,GO:0002244//hematopoietic progenitor cell differentiation,-,K11447//Transcriptional misregulation in cancer;K04257//Olfactory transduction;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K09299//Transcriptional misregulation in cancer
285971,0,0,0,0,0,0,0,0,11,0,0,0,ZNF775;zinc finger protein 775,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
285973,0,0,11,0,0,0,72,8,37,0,2,0,ATG9B;autophagy related 9B,GO:0031410//cytoplasmic vesicle;GO:0000421//autophagic vacuole membrane;GO:0016021//integral component of membrane,GO:0000045//autophagic vacuole assembly,-,K13242//Metabolic pathways;Arginine and proline metabolism;Calcium signaling pathway;VEGF signaling pathway
285989,0,0,0,0,18,0,0,22,20,0,53,0,ZNF789;zinc finger protein 789,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
286,74,0,0,0,0,9,29,0,98,53,18,0,"ANK1;ankyrin 1, erythrocytic",GO:0030018//Z disc;GO:0005856//cytoskeleton;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0031430//M band;GO:0005634//nucleus;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0042383//sarcolemma;GO:0014731//spectrin-associated cytoskeleton;GO:0030863//cortical cytoskeleton;GO:0030673//axolemma;GO:0016529//sarcoplasmic reticulum,GO:0015672//monovalent inorganic cation transport;GO:0072661//protein targeting to plasma membrane;GO:0048821//erythrocyte development;GO:0007165//signal transduction;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0006887//exocytosis;GO:0007010//cytoskeleton organization;GO:0007411//axon guidance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0010638//positive regulation of organelle organization,GO:0019899//enzyme binding;GO:0030507//spectrin binding;GO:0005200//structural constituent of cytoskeleton;GO:0008093//cytoskeletal adaptor activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0051117//ATPase binding,-
286006,0,0,0,0,0,0,18,0,15,0,0,0,LSMEM1;leucine-rich single-pass membrane protein 1,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,-,-,-
286016,0,0,0,0,0,0,0,0,25,0,0,0,TPI1P2;triosephosphate isomerase 1 pseudogene 2,-,-,-,K01803//Fructose and mannose metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Inositol phosphate metabolism
286042,0,0,0,0,0,0,0,0,48,0,19,0,"FAM86B3P;family with sequence similarity 86, member A pseudogene",-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K09057//Circadian rhythm - fly;K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation
286046,0,0,0,7,4,0,0,0,10,0,21,0,"XKR6;XK, Kell blood group complex subunit-related family, member 6",GO:0016021//integral component of membrane,-,-,K08008//Leukocyte transendothelial migration;Phagosome;Osteoclast differentiation
286053,0,28,0,16,0,0,0,0,0,0,0,0,"NSMCE2;non-SMC element 2, MMS21 homolog (S. cerevisiae)","GO:0016605//PML body;GO:0030915//Smc5-Smc6 complex;GO:0000781//chromosome, telomeric region;GO:0005634//nucleus",GO:0007067//mitotic nuclear division;GO:0090398//cellular senescence;GO:0000724//double-strand break repair via homologous recombination;GO:0000722//telomere maintenance via recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0016925//protein sumoylation;GO:0034184//positive regulation of maintenance of mitotic sister chromatid cohesion,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019789//SUMO ligase activity,-
286075,0,0,0,0,0,20,80,5,37,94,0,206,ZNF707;zinc finger protein 707,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
286077,69,0,0,5,0,28,44,109,25,0,14,0,"FAM83H;family with sequence similarity 83, member H",-,GO:0031214//biomineral tissue development,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K04257//Olfactory transduction
286097,67,0,0,8,0,0,0,0,12,85,0,0,"MICU3;mitochondrial calcium uptake family, member 3",GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,GO:0005509//calcium ion binding,-
2861,0,0,0,0,0,0,0,0,19,0,0,0,GPR37;G protein-coupled receptor 37 (endothelin receptor type B-like),GO:0000151//ubiquitin ligase complex;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex;GO:0005886//plasma membrane,GO:0042416//dopamine biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045964//positive regulation of dopamine metabolic process;GO:0031987//locomotion involved in locomotory behavior,GO:0004930//G-protein coupled receptor activity;GO:0031625//ubiquitin protein ligase binding;GO:0030544//Hsp70 protein binding;GO:0031072//heat shock protein binding,K04243//Parkinson's disease
286101,0,26,0,54,157,0,0,1,0,0,0,0,"ZNF252P;zinc finger protein 252, pseudogene",-,-,-,-
286102,0,120,14,194,104,0,0,126,0,0,183,0,TMED10P1;transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
286103,0,234,41,142,132,10,66,44,0,0,105,0,ZNF252P-AS1;ZNF252P antisense RNA 1,-,-,-,-
286122,0,0,0,0,0,0,0,0,2,0,0,0,C8orf31;chromosome 8 open reading frame 31,-,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
286128,0,0,0,0,0,0,17,0,20,197,1,0,ZFP41;ZFP41 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
286133,0,0,0,0,0,0,0,77,38,264,0,0,"SCARA5;scavenger receptor class A, member 5 (putative)",GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0034755//iron ion transmembrane transport;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0010468//regulation of gene expression;GO:0070207//protein homotrimerization;GO:0034605//cellular response to heat;GO:0006879//cellular iron ion homeostasis;GO:0030193//regulation of blood coagulation,GO:0070287//ferritin receptor activity;GO:0005044//scavenger receptor activity,K06558//Phagosome
286135,0,0,0,0,0,0,0,31,52,0,0,0,"FAM183CP;family with sequence similarity 183, member C, pseudogene",-,-,-,-
286140,0,1,0,7,29,0,0,1,0,0,8,0,"RNF5P1;ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1",-,-,-,K10666//Protein processing in endoplasmic reticulum
286144,0,72,48,40,74,0,0,0,48,0,0,0,TRIQK;triple QxxK/R motif containing,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
286148,0,0,0,0,1,23,0,0,44,135,3,0,DPY19L4;dpy-19-like 4 (C. elegans),GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",K11447//Transcriptional misregulation in cancer
286151,0,0,0,0,0,0,0,60,17,7,0,0,FBXO43;F-box protein 43,GO:0005634//nucleus,GO:0016567//protein ubiquitination;GO:0045835//negative regulation of meiosis;GO:0042177//negative regulation of protein catabolic process;GO:0007126//meiotic nuclear division,GO:0008270//zinc ion binding,K10318//Oocyte meiosis
286177,0,0,0,0,0,0,0,0,2,0,0,0,LOC286177;uncharacterized LOC286177,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
286187,0,0,0,0,0,0,9,0,0,0,0,0,"PPP1R42;protein phosphatase 1, regulatory subunit 42",GO:0002177//manchette;GO:0015630//microtubule cytoskeleton;GO:0005815//microtubule organizing center;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0010921//regulation of phosphatase activity,GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0045502//dynein binding,-
286190,0,193,1,183,162,0,30,0,7,0,147,0,LOC286190;uncharacterized LOC286190,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
2862,0,0,0,0,0,0,24,0,5,0,4,0,MLNR;motilin receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007586//digestion,GO:0016520//growth hormone-releasing hormone receptor activity;GO:0004930//G-protein coupled receptor activity,K05266//Neuroactive ligand-receptor interaction
286204,6,1,4,35,64,0,21,120,100,115,138,0,CRB2;crumbs family member 2,GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0001707//mesoderm formation;GO:0072358//cardiovascular system development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0030513//positive regulation of BMP signaling pathway;GO:0001756//somitogenesis;GO:0014028//notochord formation;GO:0045199//maintenance of epithelial cell apical/basal polarity;GO:0010951//negative regulation of endopeptidase activity,GO:0019899//enzyme binding;GO:0005509//calcium ion binding;GO:0019828//aspartic-type endopeptidase inhibitor activity,K02599//Notch signaling pathway;Dorso-ventral axis formation;Prion diseases
286205,0,0,0,43,45,94,84,0,71,0,1,542,SCAI;suppressor of cancer cell invasion,GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0035024//negative regulation of Rho protein signal transduction;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0030336//negative regulation of cell migration",GO:0003714//transcription corepressor activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K14317//Epstein-Barr virus infection;RNA transport
286207,0,69,75,42,48,21,0,59,48,0,105,1,C9orf117;chromosome 9 open reading frame 117,-,-,-,K04514//Focal adhesion;Pathogenic Escherichia coli infection;Regulation of actin cytoskeleton;Wnt signaling pathway;Vascular smooth muscle contraction;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Salmonella infection;Axon guidance;Chemokine signaling pathway;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
286223,0,0,0,0,10,25,0,1,8,0,0,0,C9orf47;chromosome 9 open reading frame 47,GO:0005576//extracellular region,-,-,-
286234,0,0,0,0,0,7,25,0,24,0,0,0,"SPATA31E1;SPATA31 subfamily E, member 1",GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007283//spermatogenesis,-,-
286256,0,0,0,0,0,9,0,0,0,0,0,0,LCN12;lipocalin 12,GO:0005576//extracellular region,GO:0006629//lipid metabolic process;GO:0006810//transport,GO:0005215//transporter activity;GO:0001972//retinoic acid binding,K01830//Arachidonic acid metabolism;Metabolic pathways
286262,0,0,0,1,0,0,0,0,0,0,2,0,TPRN;taperin,GO:0032420//stereocilium,GO:0007605//sensory perception of sound,GO:0019902//phosphatase binding,-
286297,5,0,0,0,0,0,1,0,0,0,0,0,LOC286297;uncharacterized LOC286297,-,-,-,K13402//One carbon pool by folate;Metabolic pathways
2863,42,0,55,9,14,0,0,1,13,0,149,0,GPR39;G protein-coupled receptor 39,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0046872//metal ion binding,-
286319,78,438,316,361,485,27,97,1048,86,0,497,2,TUSC1;tumor suppressor candidate 1,-,-,-,-
286333,2,0,0,0,0,1,0,0,0,0,0,0,"FAM225A;family with sequence similarity 225, member A (non-protein coding)",-,-,-,-
286336,0,1,0,0,0,11,0,0,6,5,0,0,"FAM78A;family with sequence similarity 78, member A",-,-,-,-
286343,1,0,0,0,0,0,0,22,14,90,0,0,LURAP1L;leucine rich adaptor protein 1-like,-,-,-,-
286362,0,0,0,0,0,0,0,0,18,0,0,0,"OR13C9;olfactory receptor, family 13, subfamily C, member 9",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
286365,0,0,0,17,0,1,0,0,0,0,0,0,"OR13D1;olfactory receptor, family 13, subfamily D, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
286380,1,0,0,0,0,37,5,16,1,0,0,0,FOXD4L3;forkhead box D4-like 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
286410,0,0,0,0,0,29,16,0,109,0,0,0,"ATP11C;ATPase, class VI, type 11C",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005765//lysosomal membrane,GO:0045579//positive regulation of B cell differentiation;GO:0008152//metabolic process;GO:0055085//transmembrane transport;GO:0002329//pre-B cell differentiation;GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity,K01530//Purine metabolism
286436,0,0,0,0,0,0,0,0,10,0,18,0,"H2BFM;H2B histone family, member M",GO:0000786//nucleosome;GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Systemic lupus erythematosus;Alcoholism
286451,0,0,0,8,20,0,0,0,2,0,0,0,"YIPF6;Yip1 domain family, member 6",GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane;GO:0030134//ER to Golgi transport vesicle;GO:0005783//endoplasmic reticulum;GO:0005802//trans-Golgi network,GO:0060576//intestinal epithelial cell development,GO:0042802//identical protein binding,K11447//Transcriptional misregulation in cancer
286467,0,0,0,0,0,8,0,0,0,0,0,0,FIRRE;firre intergenic repeating RNA element,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
286480,0,0,0,0,0,0,21,0,1,0,0,0,UBE2E4P;ubiquitin-conjugating enzyme E2E 4 pseudogene,-,-,-,K06689//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis;Shigellosis
286495,60,0,0,0,1,14,0,0,9,0,3,0,TTC3P1;tetratricopeptide repeat domain 3 pseudogene 1,-,-,-,-
286499,0,0,0,0,0,0,0,0,34,0,0,0,"FAM133A;family with sequence similarity 133, member A",-,-,-,-
2865,77,0,0,0,0,21,0,84,34,0,15,0,FFAR3;free fatty acid receptor 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0014061//regulation of norepinephrine secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0002385//mucosal immune response;GO:0071398//cellular response to fatty acid;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0032722//positive regulation of chemokine production;GO:0046885//regulation of hormone biosynthetic process;GO:0045776//negative regulation of blood pressure;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0008289//lipid binding,-
286514,0,0,0,0,0,0,0,0,35,0,0,0,"MAGEB18;melanoma antigen family B, 18",GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
286527,0,0,0,0,0,29,0,0,0,0,0,0,TMSB15B;thymosin beta 15B,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0042989//sequestering of actin monomers;GO:0030036//actin cytoskeleton organization,GO:0003779//actin binding,K05764//Regulation of actin cytoskeleton
286530,21,0,0,0,0,9,1,0,2,0,4,0,"P2RY8;purinergic receptor P2Y, G-protein coupled, 8",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0045028//G-protein coupled purinergic nucleotide receptor activity,K08386//Neuroactive ligand-receptor interaction
286554,0,0,0,0,8,0,0,0,0,0,0,0,BCORP1;BCL6 corepressor pseudogene 1,-,-,-,K06264//ECM-receptor interaction
286676,92,11,0,0,1,15,0,0,0,0,11,0,ILDR1;immunoglobulin-like domain containing receptor 1,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0006898//receptor-mediated endocytosis;GO:0090277//positive regulation of peptide hormone secretion,GO:0070506//high-density lipoprotein particle receptor activity,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
2867,0,0,0,0,0,10,0,0,13,0,0,0,FFAR2;free fatty acid receptor 2,GO:0005886//plasma membrane;GO:0042995//cell projection;GO:0005887//integral component of plasma membrane,GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0071398//cellular response to fatty acid;GO:0002385//mucosal immune response;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0019915//lipid storage;GO:0007186//G-protein coupled receptor signaling pathway;GO:2000484//positive regulation of interleukin-8 secretion;GO:0042593//glucose homeostasis;GO:0032722//positive regulation of chemokine production;GO:0045444//fat cell differentiation,GO:0008289//lipid binding;GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding,-
286753,0,0,0,0,1,21,47,0,11,0,0,0,TUSC5;tumor suppressor candidate 5,GO:0016021//integral component of membrane,GO:0009607//response to biotic stimulus,-,-
2868,103,0,1,0,7,0,19,0,37,0,0,0,GRK4;G protein-coupled receptor kinase 4,GO:0030425//dendrite;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0005938//cell cortex,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0031623//receptor internalization;GO:0002031//G-protein coupled receptor internalization;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0004703//G-protein coupled receptor kinase activity;GO:0005524//ATP binding;GO:0050254//rhodopsin kinase activity,K08291//Endocytosis;Morphine addiction;Chemokine signaling pathway
286826,0,0,0,0,10,22,0,41,31,0,13,0,LIN9;lin-9 homolog (C. elegans),GO:0005654//nucleoplasm;GO:0017053//transcriptional repressor complex,"GO:0006351//transcription, DNA-templated;GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle",GO:0005515//protein binding,-
286827,85,0,0,0,0,12,0,0,25,0,0,0,TRIM59;tripartite motif containing 59,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0016567//protein ubiquitination;GO:0046597//negative regulation of viral entry into host cell;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response,GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
286887,0,0,0,0,0,31,2,0,0,0,0,0,KRT6C;keratin 6C,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament,GO:0045104//intermediate filament cytoskeleton organization,GO:0005198//structural molecule activity,-
2869,43,0,0,0,0,17,20,0,18,0,9,0,GRK5;G protein-coupled receptor kinase 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0043066//negative regulation of apoptotic process;GO:0007217//tachykinin receptor signaling pathway;GO:0006915//apoptotic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0016055//Wnt signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0005543//phospholipid binding;GO:0004703//G-protein coupled receptor kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005080//protein kinase C binding;GO:0005515//protein binding,K08291//Chemokine signaling pathway;Endocytosis;Morphine addiction
287,0,0,0,0,0,73,133,37,127,93,0,0,"ANK2;ankyrin 2, neuronal",GO:0014704//intercalated disc;GO:0043005//neuron projection;GO:0005856//cytoskeleton;GO:0030018//Z disc;GO:0016323//basolateral plasma membrane;GO:0031430//M band;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0030315//T-tubule;GO:0045121//membrane raft;GO:0043034//costamere;GO:0016324//apical plasma membrane;GO:0042383//sarcolemma;GO:0005622//intracellular;GO:0031672//A band;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,GO:0055117//regulation of cardiac muscle contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:1901021//positive regulation of calcium ion transmembrane transporter activity;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0060048//cardiac muscle contraction;GO:0086014//atrial cardiac muscle cell action potential;GO:0036371//protein localization to T-tubule;GO:0070972//protein localization to endoplasmic reticulum;GO:0010628//positive regulation of gene expression;GO:0034394//protein localization to cell surface;GO:0051928//positive regulation of calcium ion transport;GO:0086004//regulation of cardiac muscle cell contraction;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0086015//SA node cell action potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0051924//regulation of calcium ion transport;GO:0003283//atrial septum development;GO:0043268//positive regulation of potassium ion transport;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0072661//protein targeting to plasma membrane;GO:0030913//paranodal junction assembly;GO:0006874//cellular calcium ion homeostasis;GO:0086046//membrane depolarization during SA node cell action potential;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0007411//axon guidance;GO:0031647//regulation of protein stability;GO:0050821//protein stabilization;GO:0072659//protein localization to plasma membrane;GO:0086070//SA node cell to atrial cardiac muscle cell communication;GO:0051597//response to methylmercury;GO:0033292//T-tubule organization;GO:0033365//protein localization to organelle;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0002027//regulation of heart rate;GO:0034613//cellular protein localization;GO:0036309//protein localization to M-band;GO:2001259//positive regulation of cation channel activity,"GO:0030507//spectrin binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0005200//structural constituent of cytoskeleton;GO:0019899//enzyme binding;GO:0051117//ATPase binding;GO:0030674//protein binding, bridging;GO:0015459//potassium channel regulator activity;GO:0019901//protein kinase binding",-
2870,49,0,0,0,2,0,15,0,18,1,8,0,GRK6;G protein-coupled receptor kinase 6,GO:0016020//membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006468//protein phosphorylation;GO:0016055//Wnt signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005524//ATP binding;GO:0004703//G-protein coupled receptor kinase activity;GO:0005515//protein binding,K08291//Chemokine signaling pathway;Morphine addiction;Endocytosis
287015,160,0,0,0,0,0,0,0,4,0,9,0,TRIM42;tripartite motif containing 42,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
2872,0,50,0,4,57,4,0,0,43,0,0,0,MKNK2;MAP kinase interacting serine/threonine kinase 2,GO:0005730//nucleolus;GO:0016605//PML body;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0030097//hemopoiesis;GO:0007166//cell surface receptor signaling pathway;GO:0006417//regulation of translation;GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0071243//cellular response to arsenic-containing substance,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04372//Insulin signaling pathway;MAPK signaling pathway
2873,0,2,1,0,16,20,12,1,33,0,1,0,GPS1;G protein pathway suppressor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0008180//COP9 signalosome,GO:0010388//cullin deneddylation;GO:0000188//inactivation of MAPK activity;GO:0007254//JNK cascade;GO:0007049//cell cycle,GO:0005515//protein binding;GO:0005095//GTPase inhibitor activity,-
2874,0,0,0,0,19,3,0,0,11,0,0,0,GPS2;G protein pathway suppressor 2,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex,GO:0007254//JNK cascade;GO:0046329//negative regulation of JNK cascade;GO:0007049//cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000188//inactivation of MAPK activity,GO:0003714//transcription corepressor activity;GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding,K15307//HTLV-I infection
2875,0,0,0,0,13,13,0,154,0,259,11,0,GPT;glutamic-pyruvate transaminase (alanine aminotransferase),GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0008652//cellular amino acid biosynthetic process;GO:0042853//L-alanine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process,GO:0004021//L-alanine:2-oxoglutarate aminotransferase activity;GO:0030170//pyridoxal phosphate binding,"K00814//Carbon fixation in photosynthetic organisms;Metabolic pathways;Microbial metabolism in diverse environments;Alanine, aspartate and glutamate metabolism"
2876,0,25,0,7,17,0,17,1,1,151,11,0,GPX1;glutathione peroxidase 1,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,"GO:0010269//response to selenium ion;GO:0042542//response to hydrogen peroxide;GO:0043066//negative regulation of apoptotic process;GO:0060055//angiogenesis involved in wound healing;GO:0051897//positive regulation of protein kinase B signaling;GO:0009749//response to glucose;GO:0043403//skeletal muscle tissue regeneration;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048741//skeletal muscle fiber development;GO:0009636//response to toxic substance;GO:0051450//myoblast proliferation;GO:0019369//arachidonic acid metabolic process;GO:0019372//lipoxygenase pathway;GO:0042311//vasodilation;GO:0007568//aging;GO:0051593//response to folic acid;GO:0034599//cellular response to oxidative stress;GO:0018158//protein oxidation;GO:0061136//regulation of proteasomal protein catabolic process;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0035094//response to nicotine;GO:0032355//response to estradiol;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0043523//regulation of neuron apoptotic process;GO:0010332//response to gamma radiation;GO:0001659//temperature homeostasis;GO:0040029//regulation of gene expression, epigenetic;GO:0060047//heart contraction;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0042744//hydrogen peroxide catabolic process;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0007605//sensory perception of sound;GO:0009650//UV protection;GO:0009410//response to xenobiotic stimulus;GO:0006982//response to lipid hydroperoxide;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0044281//small molecule metabolic process;GO:0006749//glutathione metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006641//triglyceride metabolic process;GO:0045454//cell redox homeostasis;GO:0043534//blood vessel endothelial cell migration;GO:0001885//endothelial cell development;GO:0045444//fat cell differentiation;GO:0009609//response to symbiotic bacterium;GO:0006195//purine nucleotide catabolic process;GO:0051702//interaction with symbiont;GO:0002862//negative regulation of inflammatory response to antigenic stimulus",GO:0047066//phospholipid-hydroperoxide glutathione peroxidase activity;GO:0008430//selenium binding;GO:0017124//SH3 domain binding;GO:0004602//glutathione peroxidase activity;GO:0043295//glutathione binding,K00432//Arachidonic acid metabolism;Two-component system;Metabolic pathways;Amyotrophic lateral sclerosis (ALS);Huntington's disease;Glutathione metabolism;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
2877,0,0,55,0,25,0,0,0,15,0,0,0,GPX2;glutathione peroxidase 2 (gastrointestinal),GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0001659//temperature homeostasis;GO:0009609//response to symbiotic bacterium;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0051702//interaction with symbiont;GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process,GO:0004602//glutathione peroxidase activity;GO:0009055//electron carrier activity,K00432//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Glutathione metabolism;Huntington's disease;Arachidonic acid metabolism;Two-component system;Metabolic pathways;Amyotrophic lateral sclerosis (ALS)
2878,0,0,0,3,34,13,0,0,2,0,5,0,GPX3;glutathione peroxidase 3 (plasma),GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0055114//oxidation-reduction process;GO:0051289//protein homotetramerization;GO:0042744//hydrogen peroxide catabolic process;GO:0006982//response to lipid hydroperoxide,GO:0008134//transcription factor binding;GO:0008430//selenium binding;GO:0004602//glutathione peroxidase activity,K00432//Two-component system;Arachidonic acid metabolism;Amyotrophic lateral sclerosis (ALS);Metabolic pathways;Huntington's disease;Glutathione metabolism;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
2879,125,121,1,16,29,0,0,0,4,0,0,1,GPX4;glutathione peroxidase 4,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005635//nuclear envelope;GO:0005634//nucleus,GO:0019372//lipoxygenase pathway;GO:0019369//arachidonic acid metabolic process;GO:0006749//glutathione metabolic process;GO:0055114//oxidation-reduction process;GO:0050727//regulation of inflammatory response;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006325//chromatin organization;GO:0006644//phospholipid metabolic process;GO:0007568//aging;GO:0042744//hydrogen peroxide catabolic process;GO:0032355//response to estradiol;GO:0044281//small molecule metabolic process,GO:0047066//phospholipid-hydroperoxide glutathione peroxidase activity;GO:0004602//glutathione peroxidase activity;GO:0008430//selenium binding;GO:0043295//glutathione binding,K05361//Glutathione metabolism
288,123,72,0,16,137,72,60,60,82,0,8,299,"ANK3;ankyrin 3, node of Ranvier (ankyrin G)",GO:0033270//paranode region of axon;GO:0030018//Z disc;GO:0016328//lateral plasma membrane;GO:0031594//neuromuscular junction;GO:0014704//intercalated disc;GO:0030425//dendrite;GO:0009986//cell surface;GO:0005764//lysosome;GO:0009925//basal plasma membrane;GO:0016529//sarcoplasmic reticulum;GO:0043194//axon initial segment;GO:0016323//basolateral plasma membrane;GO:0033268//node of Ranvier;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0043034//costamere;GO:0030315//T-tubule;GO:0045211//postsynaptic membrane;GO:0005923//tight junction;GO:0014731//spectrin-associated cytoskeleton;GO:0042383//sarcolemma,GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0007165//signal transduction;GO:0043001//Golgi to plasma membrane protein transport;GO:0045838//positive regulation of membrane potential;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0045184//establishment of protein localization;GO:1900827//positive regulation of membrane depolarization during cardiac muscle cell action potential;GO:0007409//axonogenesis;GO:0007528//neuromuscular junction development;GO:0072660//maintenance of protein location in plasma membrane;GO:0043266//regulation of potassium ion transport;GO:0010765//positive regulation of sodium ion transport;GO:0000281//mitotic cytokinesis;GO:0090314//positive regulation of protein targeting to membrane;GO:0071709//membrane assembly;GO:0072661//protein targeting to plasma membrane;GO:0010650//positive regulation of cell communication by electrical coupling;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0010628//positive regulation of gene expression;GO:0007411//axon guidance;GO:0019228//neuronal action potential;GO:0007009//plasma membrane organization;GO:0072659//protein localization to plasma membrane,"GO:0045296//cadherin binding;GO:0030674//protein binding, bridging;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0030507//spectrin binding;GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton",-
2880,0,0,0,0,0,0,35,0,28,0,0,0,GPX5;glutathione peroxidase 5 (epididymal androgen-related protein),GO:0005576//extracellular region,GO:0006629//lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0006979//response to oxidative stress,GO:0004602//glutathione peroxidase activity,K00432//Huntington's disease;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Glutathione metabolism;Arachidonic acid metabolism;Two-component system;Metabolic pathways;Amyotrophic lateral sclerosis (ALS)
2882,116,0,0,0,0,0,0,99,0,0,0,0,GPX7;glutathione peroxidase 7,GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region,GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process,GO:0004602//glutathione peroxidase activity;GO:0004601//peroxidase activity,K00432//Arachidonic acid metabolism;Two-component system;Metabolic pathways;Amyotrophic lateral sclerosis (ALS);Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Glutathione metabolism;Huntington's disease
2885,0,19,0,3,90,0,0,0,16,0,13,0,GRB2;growth factor receptor-bound protein 2,GO:0012506//vesicle membrane;GO:0005829//cytosol;GO:0008180//COP9 signalosome;GO:0070436//Grb2-EGFR complex;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0043408//regulation of MAPK cascade;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007411//axon guidance;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0007265//Ras protein signal transduction;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0009967//positive regulation of signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071479//cellular response to ionizing radiation;GO:0031295//T cell costimulation;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0051291//protein heterooligomerization;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0042770//signal transduction in response to DNA damage;GO:0050900//leukocyte migration;GO:0031623//receptor internalization;GO:0016032//viral process;GO:0007568//aging;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030838//positive regulation of actin filament polymerization,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0043560//insulin receptor substrate binding;GO:0005154//epidermal growth factor receptor binding;GO:0001784//phosphotyrosine binding;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0019903//protein phosphatase binding;GO:0046875//ephrin receptor binding;GO:0005070//SH3/SH2 adaptor activity,K04364//MAPK signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Chronic myeloid leukemia;ErbB signaling pathway;Renal cell carcinoma;Gap junction;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Insulin signaling pathway;Prostate cancer;Alcoholism;Non-small cell lung cancer;Endometrial cancer;MAPK signaling pathway - fly;Osteoclast differentiation;Hepatitis C;Neurotrophin signaling pathway;Glioma;Focal adhesion;Dorso-ventral axis formation;Fc epsilon RI signaling pathway;Jak-STAT signaling pathway;Acute myeloid leukemia;B cell receptor signaling pathway
2886,0,0,0,3,6,50,0,53,24,0,9,0,GRB7;growth factor receptor-bound protein 7,GO:0042995//cell projection;GO:0010494//cytoplasmic stress granule;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0009967//positive regulation of signal transduction;GO:0017148//negative regulation of translation;GO:0030335//positive regulation of cell migration;GO:0050900//leukocyte migration;GO:0034063//stress granule assembly;GO:0007596//blood coagulation;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005070//SH3/SH2 adaptor activity;GO:0003723//RNA binding,K07360//NF-kappa B signaling pathway;Natural killer cell mediated cytotoxicity;Primary immunodeficiency;T cell receptor signaling pathway;K05855//Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;Fc gamma R-mediated phagocytosis;Tuberculosis;B cell receptor signaling pathway;Osteoclast differentiation;Natural killer cell mediated cytotoxicity;Epstein-Barr virus infection;K08888//Neurotrophin signaling pathway
2887,83,17,1,0,39,12,21,74,38,0,0,0,GRB10;growth factor receptor-bound protein 10,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0042326//negative regulation of phosphorylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0042327//positive regulation of phosphorylation;GO:0032868//response to insulin;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway,GO:0005158//insulin receptor binding;GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07360//T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Primary immunodeficiency;NF-kappa B signaling pathway;K05855//Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;B cell receptor signaling pathway;Tuberculosis;Fc gamma R-mediated phagocytosis;Natural killer cell mediated cytotoxicity;Osteoclast differentiation;Epstein-Barr virus infection
2888,0,0,0,0,0,0,12,0,40,117,0,0,GRB14;growth factor receptor-bound protein 14,GO:0000139//Golgi membrane;GO:0010008//endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007596//blood coagulation;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity,K05855//B cell receptor signaling pathway;Tuberculosis;Fc gamma R-mediated phagocytosis;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Epstein-Barr virus infection;Natural killer cell mediated cytotoxicity;Osteoclast differentiation;K07293//Jak-STAT signaling pathway;Leukocyte transendothelial migration;Natural killer cell mediated cytotoxicity;Herpes simplex infection;Adipocytokine signaling pathway;MAPK signaling pathway - fly;Chronic myeloid leukemia;Neurotrophin signaling pathway;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection
2889,0,25,0,5,17,34,0,5,46,56,26,0,RAPGEF1;Rap guanine nucleotide exchange factor (GEF) 1,GO:0005829//cytosol;GO:0005768//endosome;GO:0005769//early endosome,GO:0071320//cellular response to cAMP;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:1990090//cellular response to nerve growth factor stimulus;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007165//signal transduction;GO:0032486//Rap protein signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0000186//activation of MAPKK activity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0032854//positive regulation of Rap GTPase activity;GO:0061028//establishment of endothelial barrier;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038180//nerve growth factor signaling pathway;GO:1901888//regulation of cell junction assembly;GO:0001568//blood vessel development,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0017034//Rap guanyl-nucleotide exchange factor activity,K06277//Insulin signaling pathway;Neurotrophin signaling pathway;Focal adhesion;Renal cell carcinoma
2890,0,0,0,0,0,0,14,31,75,0,6,0,"GRIA1;glutamate receptor, ionotropic, AMPA 1",GO:0044309//neuron spine;GO:0030666//endocytic vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032590//dendrite membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0008021//synaptic vesicle;GO:0009986//cell surface;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0043197//dendritic spine;GO:0043025//neuronal cell body,"GO:0007616//long-term memory;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0007165//signal transduction;GO:0031623//receptor internalization;GO:0007268//synaptic transmission",GO:0030165//PDZ domain binding;GO:0004971//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0008066//glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005515//protein binding,K05197//Glutamatergic synapse;Amphetamine addiction;Amyotrophic lateral sclerosis (ALS);Dopaminergic synapse;Long-term depression;Nicotine addiction;Retrograde endocannabinoid signaling;Long-term potentiation;Neuroactive ligand-receptor interaction
2891,0,0,0,0,0,0,0,0,41,114,2,0,"GRIA2;glutamate receptor, ionotropic, AMPA 2",GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0030666//endocytic vesicle membrane;GO:0045211//postsynaptic membrane;GO:0008021//synaptic vesicle;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction,"GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport",GO:0005515//protein binding;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0004971//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0004970//ionotropic glutamate receptor activity,K05198//Long-term depression;Nicotine addiction;Dopaminergic synapse;Cocaine addiction;Long-term potentiation;Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Amyotrophic lateral sclerosis (ALS);Glutamatergic synapse;Amphetamine addiction
2892,103,0,0,0,0,47,55,0,54,0,0,0,"GRIA3;glutamate receptor, ionotropic, AMPA 3",GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0045211//postsynaptic membrane,"GO:0007215//glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport;GO:0006810//transport",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0004971//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,K05199//Amphetamine addiction;Glutamatergic synapse;Transcriptional misregulation in cancer;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction;Dopaminergic synapse;Long-term depression;Nicotine addiction
2893,109,0,0,0,0,16,80,0,36,73,0,0,"GRIA4;glutamate receptor, ionotropic, AMPA 4",GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0031982//vesicle,"GO:0007268//synaptic transmission;GO:0007215//glutamate receptor signaling pathway;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport;GO:0006810//transport",GO:0004970//ionotropic glutamate receptor activity;GO:0004971//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity,K05200//Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Nicotine addiction;Dopaminergic synapse;Glutamatergic synapse;Amphetamine addiction
2894,233,0,22,0,0,0,58,0,68,0,0,0,"GRID1;glutamate receptor, ionotropic, delta 1",GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0008328//ionotropic glutamate receptor complex,"GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport;GO:0035176//social behavior;GO:0035235//ionotropic glutamate receptor signaling pathway",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity,K05206//Neuroactive ligand-receptor interaction
2895,0,0,0,0,0,20,5,0,8,174,7,0,"GRID2;glutamate receptor, ionotropic, delta 2",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0008328//ionotropic glutamate receptor complex,"GO:0010975//regulation of neuron projection development;GO:0006810//transport;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0034613//cellular protein localization;GO:0043523//regulation of neuron apoptotic process;GO:0060134//prepulse inhibition;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0021707//cerebellar granule cell differentiation;GO:0007215//glutamate receptor signaling pathway",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0008066//glutamate receptor activity;GO:0097110//scaffold protein binding;GO:0030165//PDZ domain binding;GO:0004970//ionotropic glutamate receptor activity,K05207//Long-term depression;Neuroactive ligand-receptor interaction
28951,0,1,0,9,68,0,20,0,3,0,28,0,TRIB2;tribbles pseudokinase 2,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0045599//negative regulation of fat cell differentiation;GO:0006469//negative regulation of protein kinase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006468//protein phosphorylation;GO:0045081//negative regulation of interleukin-10 biosynthetic process;GO:0043405//regulation of MAP kinase activity,GO:0031625//ubiquitin protein ligase binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0004860//protein kinase inhibitor activity;GO:0004672//protein kinase activity;GO:0000166//nucleotide binding;GO:0008134//transcription factor binding,-
28952,0,1,0,1,0,11,13,1,18,9,1,0,CCDC22;coiled-coil domain containing 22,-,-,-,-
28954,0,0,0,0,0,29,2,0,11,67,0,0,REM1;RAS (RAD and GEM)-like GTP-binding 1,GO:0016020//membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005516//calmodulin binding;GO:0005525//GTP binding,-
28955,0,0,0,0,0,0,0,0,10,0,3,0,DEXI;Dexi homolog (mouse),-,-,-,-
28956,0,26,1,3,18,2,0,0,6,8,0,0,"LAMTOR2;late endosomal/lysosomal adaptor, MAPK and MTOR activator 2",GO:0005770//late endosome;GO:0071986//Ragulator complex;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane,GO:0071230//cellular response to amino acid stimulus;GO:0016049//cell growth;GO:0000186//activation of MAPKK activity;GO:0034613//cellular protein localization;GO:0043547//positive regulation of GTPase activity;GO:0032008//positive regulation of TOR signaling,GO:0032947//protein complex scaffold;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
28957,0,0,0,3,1,0,15,0,0,0,0,0,MRPS28;mitochondrial ribosomal protein S28,GO:0005739//mitochondrion;GO:0005763//mitochondrial small ribosomal subunit,-,GO:0044822//poly(A) RNA binding,-
28958,0,58,0,1,22,0,0,0,0,0,0,6,COA3;cytochrome c oxidase assembly factor 3,GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane,GO:0070131//positive regulation of mitochondrial translation;GO:0033617//mitochondrial respiratory chain complex IV assembly,GO:0005515//protein binding,-
28959,0,6,1,0,0,0,0,0,7,43,15,0,TMEM176B;transmembrane protein 176B,GO:0016021//integral component of membrane;GO:0031965//nuclear membrane,GO:0009887//organ morphogenesis;GO:0030154//cell differentiation;GO:2001199//negative regulation of dendritic cell differentiation,-,-
2896,0,0,0,0,1,0,0,17,3,0,0,0,GRN;granulin,GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0008219//cell death;GO:0007566//embryo implantation;GO:0001835//blastocyst hatching;GO:0007165//signal transduction;GO:0050679//positive regulation of epithelial cell proliferation,GO:0008083//growth factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K06233//Hedgehog signaling pathway;K02599//Prion diseases;Notch signaling pathway;Dorso-ventral axis formation;K04550//Malaria;Alzheimer's disease
28960,0,0,0,0,0,0,0,0,0,0,5,0,"DCPS;decapping enzyme, scavenger",GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0043069//negative regulation of programmed cell death;GO:0045292//mRNA cis splicing, via spliceosome;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0010467//gene expression;GO:0036245//cellular response to menadione",GO:0050072//m7G(5')pppN diphosphatase activity;GO:0005515//protein binding;GO:0000340//RNA 7-methylguanosine cap binding,K12584//RNA degradation
28962,0,0,0,0,0,4,0,0,0,0,0,0,OSTM1;osteopetrosis associated transmembrane protein 1,GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0030316//osteoclast differentiation;GO:0055085//transmembrane transport,-,K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
28964,98,0,0,5,0,17,0,42,48,0,0,0,GIT1;G protein-coupled receptor kinase interacting ArfGAP 1,GO:0016235//aggresome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005925//focal adhesion,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0005515//protein binding;GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K05737//Epithelial cell signaling in Helicobacter pylori infection;Regulation of actin cytoskeleton;Endocytosis
28965,0,0,0,0,0,0,0,0,17,0,2,0,"SLC27A6;solute carrier family 27 (fatty acid transporter), member 6",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0042383//sarcolemma,GO:0055085//transmembrane transport;GO:0001676//long-chain fatty acid metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0015909//long-chain fatty acid transport,GO:0000166//nucleotide binding;GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0031957//very long-chain fatty acid-CoA ligase activity,K08749//PPAR signaling pathway
28966,0,0,0,0,23,0,0,0,0,0,0,0,SNX24;sorting nexin 24,GO:0030659//cytoplasmic vesicle membrane,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding,-
28968,0,0,0,0,0,26,16,0,0,96,23,0,"SLC6A16;solute carrier family 6, member 16",GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0005326//neurotransmitter transporter activity;GO:0005328//neurotransmitter:sodium symporter activity,-
28969,0,32,0,0,10,0,27,0,0,0,0,0,BZW2;basic leucine zipper and W2 domains 2,GO:0016020//membrane,GO:0007399//nervous system development;GO:0030154//cell differentiation,-,K03240//RNA transport
2897,0,0,0,0,30,22,22,1,22,0,0,0,"GRIK1;glutamate receptor, ionotropic, kainate 1",GO:0032983//kainate selective glutamate receptor complex;GO:0005887//integral component of plasma membrane;GO:0097481//neuronal postsynaptic density;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite,"GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0030534//adult behavior;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0007417//central nervous system development;GO:0007215//glutamate receptor signaling pathway;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0048266//behavioral response to pain;GO:0035249//synaptic transmission, glutamatergic;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0032230//positive regulation of synaptic transmission, GABAergic",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity,K05201//Neuroactive ligand-receptor interaction;Glutamatergic synapse
28970,81,4,0,35,101,16,0,0,33,0,0,0,C11orf54;chromosome 11 open reading frame 54,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0005515//protein binding;GO:0008270//zinc ion binding",-
28971,0,0,0,0,0,0,0,0,14,0,0,0,"AAMDC;adipogenesis associated, Mth938 domain containing",GO:0005737//cytoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0045600//positive regulation of fat cell differentiation,-,-
28972,2,21,0,10,82,0,0,61,6,0,17,16,SPCS1;signal peptidase complex subunit 1 homolog (S. cerevisiae),GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005787//signal peptidase complex,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006508//proteolysis;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0006465//signal peptide processing;GO:0050796//regulation of insulin secretion,GO:0008233//peptidase activity;GO:0005515//protein binding,K12946//Protein export
28974,0,0,0,0,10,0,0,0,13,0,0,0,C19orf53;chromosome 19 open reading frame 53,-,-,-,-
28976,3,0,0,0,14,53,37,0,8,0,0,0,"ACAD9;acyl-CoA dehydrogenase family, member 9",GO:0005634//nucleus;GO:0030425//dendrite;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding,-
28977,0,12,0,38,190,22,0,0,0,0,0,0,MRPL42;mitochondrial ribosomal protein L42,GO:0005763//mitochondrial small ribosomal subunit;GO:0005739//mitochondrion;GO:0005886//plasma membrane,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K14443//RNA degradation;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
28978,0,0,0,0,6,0,0,0,0,0,0,0,TMEM14A;transmembrane protein 14A,GO:0016021//integral component of membrane,-,-,-
2898,0,0,0,0,0,0,25,0,41,0,0,0,"GRIK2;glutamate receptor, ionotropic, kainate 2",GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005887//integral component of plasma membrane;GO:0032983//kainate selective glutamate receptor complex,"GO:0006874//cellular calcium ion homeostasis;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0050806//positive regulation of synaptic transmission;GO:0035249//synaptic transmission, glutamatergic;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0019228//neuronal action potential;GO:0007215//glutamate receptor signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0006886//intracellular protein transport;GO:0001662//behavioral fear response;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0050804//regulation of synaptic transmission;GO:0006810//transport;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0034220//ion transmembrane transport;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007268//synaptic transmission",GO:0015277//kainate selective glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity,K05202//Glutamatergic synapse;Neuroactive ligand-receptor interaction
28981,0,0,0,8,35,19,16,0,11,0,14,0,IFT81;intraflagellar transport 81,GO:0097225//sperm midpiece;GO:0097228//sperm principal piece;GO:0005813//centrosome;GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0031514//motile cilium,GO:0042384//cilium assembly;GO:0007283//spermatogenesis;GO:0035735//intraciliary transport involved in cilium morphogenesis,GO:0015631//tubulin binding,K05767//Regulation of actin cytoskeleton;Adherens junction
28982,0,1,0,0,8,15,20,1,18,35,0,0,FLVCR1;feline leukemia virus subgroup C cellular receptor 1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane,GO:0046620//regulation of organ growth;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organismal development;GO:0006810//transport;GO:0097037//heme export;GO:0060323//head morphogenesis;GO:0015886//heme transport;GO:0055085//transmembrane transport;GO:0042733//embryonic digit morphogenesis;GO:0035264//multicellular organism growth;GO:0001568//blood vessel development;GO:0006879//cellular iron ion homeostasis;GO:0048536//spleen development;GO:0030218//erythrocyte differentiation;GO:0006839//mitochondrial transport;GO:0001701//in utero embryonic development;GO:0043249//erythrocyte maturation;GO:0008219//cell death,GO:0015232//heme transporter activity;GO:0005515//protein binding;GO:0005215//transporter activity,-
28983,0,0,0,0,0,0,0,0,18,0,0,0,"TMPRSS11E;transmembrane protease, serine 11E",GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0050890//cognition,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
28984,0,0,0,0,0,0,0,0,10,0,0,0,RGCC;regulator of cell cycle,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045840//positive regulation of mitosis;GO:0090272//negative regulation of fibroblast growth factor production;GO:0016525//negative regulation of angiogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0001937//negative regulation of endothelial cell proliferation;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0032967//positive regulation of collagen biosynthetic process;GO:0050715//positive regulation of cytokine secretion;GO:0006956//complement activation;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0001100//negative regulation of exit from mitosis;GO:0072537//fibroblast activation;GO:1901313//positive regulation of gene expression involved in extracellular matrix organization;GO:0008285//negative regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:2000573//positive regulation of DNA biosynthetic process;GO:0003331//positive regulation of extracellular matrix constituent secretion;GO:0071158//positive regulation of cell cycle arrest;GO:0050710//negative regulation of cytokine secretion;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:1901991//negative regulation of mitotic cell cycle phase transition;GO:0071456//cellular response to hypoxia;GO:0071850//mitotic cell cycle arrest,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0070412//R-SMAD binding;GO:0030295//protein kinase activator activity,-
28985,0,0,0,3,12,9,0,0,20,0,5,0,MCTS1;malignant T cell amplified sequence 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0022627//cytosolic small ribosomal subunit,"GO:0032790//ribosome disassembly;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006355//regulation of transcription, DNA-templated;GO:0002192//IRES-dependent translational initiation;GO:0007049//cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0001731//formation of translation preinitiation complex;GO:0006974//cellular response to DNA damage stimulus",GO:0003723//RNA binding,-
28986,0,0,0,1,0,10,0,0,11,0,17,0,"MAGEH1;melanoma antigen family H, 1",GO:0005737//cytoplasm,GO:0006915//apoptotic process,-,K12464//Neurotrophin signaling pathway
28987,0,0,0,4,23,0,29,13,14,0,28,0,NOB1;NIN1/RPN12 binding protein 1 homolog (S. cerevisiae),GO:0005634//nucleus,GO:0007601//visual perception,GO:0046872//metal ion binding,K11883//Ribosome biogenesis in eukaryotes
28988,0,23,0,24,46,1,0,0,13,0,6,1,DBNL;drebrin-like,GO:0005829//cytosol;GO:0002102//podosome;GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0030665//clathrin-coated vesicle membrane;GO:0005938//cell cortex;GO:0005737//cytoplasm,GO:0002376//immune system process;GO:0071800//podosome assembly;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0016601//Rac protein signal transduction;GO:0048812//neuron projection morphogenesis;GO:0007416//synapse assembly;GO:0006915//apoptotic process;GO:0006897//endocytosis;GO:0007257//activation of JUN kinase activity,GO:0051015//actin filament binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0003779//actin binding;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding,K06106//Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Pathogenic Escherichia coli infection
28989,0,19,130,20,53,1,25,652,15,0,60,0,NTMT1;N-terminal Xaa-Pro-Lys N-methyltransferase 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007059//chromosome segregation;GO:0035572//N-terminal peptidyl-serine dimethylation;GO:0007051//spindle organization;GO:0035573//N-terminal peptidyl-serine trimethylation;GO:0018016//N-terminal peptidyl-proline dimethylation,GO:0008276//protein methyltransferase activity,-
2899,0,0,0,0,0,36,29,0,96,0,0,604,"GRIK3;glutamate receptor, ionotropic, kainate 3",GO:0030054//cell junction;GO:0032839//dendrite cytoplasm;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0005887//integral component of plasma membrane;GO:0043195//terminal bouton;GO:0030424//axon;GO:0043204//perikaryon;GO:0032983//kainate selective glutamate receptor complex,"GO:0035249//synaptic transmission, glutamatergic;GO:0034220//ion transmembrane transport;GO:0007215//glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0042391//regulation of membrane potential;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0051967//negative regulation of synaptic transmission, glutamatergic",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0004970//ionotropic glutamate receptor activity;GO:0001640//adenylate cyclase inhibiting G-protein coupled glutamate receptor activity;GO:0008066//glutamate receptor activity;GO:0015277//kainate selective glutamate receptor activity,K05203//Neuroactive ligand-receptor interaction;Glutamatergic synapse
28990,0,90,0,52,36,0,1,112,27,0,55,1,ASTE1;asteroid homolog 1 (Drosophila),-,GO:0006281//DNA repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004518//nuclease activity,K01537//Purine metabolism
28991,0,0,0,0,12,0,26,1,0,0,0,0,COMMD5;COMM domain containing 5,GO:0005634//nucleus,-,GO:0005515//protein binding,-
28992,0,0,0,0,1,20,0,0,0,0,0,0,MACROD1;MACRO domain containing 1,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0042278//purine nucleoside metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0051725//protein de-ADP-ribosylation,"GO:0005515//protein binding;GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0019213//deacetylase activity",-
28996,96,40,4,82,569,40,52,0,47,2,2,669,HIPK2;homeodomain interacting protein kinase 2,GO:0016605//PML body;GO:0016604//nuclear body;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0061072//iris morphogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0043524//negative regulation of neuron apoptotic process;GO:0007224//smoothened signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0048596//embryonic camera-type eye morphogenesis;GO:0030578//PML body organization;GO:0006351//transcription, DNA-templated;GO:0032092//positive regulation of protein binding;GO:0043388//positive regulation of DNA binding;GO:0001654//eye development;GO:0019048//modulation by virus of host morphology or physiology;GO:0051726//regulation of cell cycle;GO:0046330//positive regulation of JNK cascade;GO:0008284//positive regulation of cell proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010842//retina layer formation;GO:0030182//neuron differentiation;GO:0006468//protein phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0030514//negative regulation of BMP signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007628//adult walking behavior;GO:0050882//voluntary musculoskeletal movement;GO:0097193//intrinsic apoptotic signaling pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0030218//erythrocyte differentiation;GO:0060395//SMAD protein signal transduction;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0060235//lens induction in camera-type eye",GO:0046790//virion binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0046332//SMAD binding;GO:0005524//ATP binding;GO:0003714//transcription corepressor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0004672//protein kinase activity,-
28999,0,0,0,1,0,0,0,129,39,119,4,0,KLF15;Kruppel-like factor 15,GO:0005634//nucleus,"GO:2000757//negative regulation of peptidyl-lysine acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:1901653//cellular response to peptide;GO:0010001//glial cell differentiation;GO:0006351//transcription, DNA-templated;GO:0015758//glucose transport",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding,-
29,93,21,0,14,50,35,19,0,75,0,7,0,ABR;active BCR-related,GO:0005829//cytosol;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0032496//response to lipopolysaccharide;GO:0032855//positive regulation of Rac GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0007420//brain development;GO:0030336//negative regulation of cell migration;GO:0097190//apoptotic signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0050885//neuromuscular process controlling balance;GO:0043065//positive regulation of apoptotic process;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0042472//inner ear morphogenesis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0043314//negative regulation of neutrophil degranulation;GO:0050766//positive regulation of phagocytosis,GO:0005096//GTPase activator activity;GO:0030675//Rac GTPase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K08878//Pathways in cancer;Chronic myeloid leukemia
290,0,1,0,1,21,17,0,66,46,0,0,0,ANPEP;alanyl (membrane) aminopeptidase,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0016032//viral process;GO:0030154//cell differentiation;GO:0001525//angiogenesis;GO:0044267//cellular protein metabolic process;GO:0002003//angiotensin maturation;GO:0009615//response to virus;GO:0006508//proteolysis,GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0001618//virus receptor activity;GO:0004872//receptor activity,K11140//Glutathione metabolism;Hematopoietic cell lineage;Renin-angiotensin system;Metabolic pathways
2900,3,1,0,0,0,0,0,96,58,163,0,0,"GRIK4;glutamate receptor, ionotropic, kainate 4",GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0032983//kainate selective glutamate receptor complex;GO:0043204//perikaryon;GO:0043195//terminal bouton;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus,"GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007215//glutamate receptor signaling pathway;GO:0006810//transport;GO:0035249//synaptic transmission, glutamatergic;GO:0031960//response to corticosteroid;GO:0034220//ion transmembrane transport",GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0015277//kainate selective glutamate receptor activity,K05204//Glutamatergic synapse;Neuroactive ligand-receptor interaction
2901,0,0,0,0,0,0,0,0,5,0,0,0,"GRIK5;glutamate receptor, ionotropic, kainate 5",GO:0014069//postsynaptic density;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0005783//endoplasmic reticulum;GO:0043195//terminal bouton;GO:0032983//kainate selective glutamate receptor complex;GO:0043204//perikaryon,"GO:0031630//regulation of synaptic vesicle fusion to presynaptic membrane;GO:0043113//receptor clustering;GO:0007268//synaptic transmission;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0071333//cellular response to glucose stimulus;GO:0006621//protein retention in ER lumen;GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0043525//positive regulation of neuron apoptotic process;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0051649//establishment of localization in cell",GO:0017124//SH3 domain binding;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0042802//identical protein binding;GO:0030165//PDZ domain binding;GO:0015277//kainate selective glutamate receptor activity,K05205//Neuroactive ligand-receptor interaction;Glutamatergic synapse
29015,0,0,0,0,0,0,7,0,0,0,4,0,"SLC43A3;solute carrier family 43, member 3",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
2902,0,43,56,23,22,0,14,459,101,18,154,110,"GRIN1;glutamate receptor, ionotropic, N-methyl D-aspartate 1",GO:0043197//dendritic spine;GO:0014069//postsynaptic density;GO:0030425//dendrite;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0045202//synapse;GO:0009986//cell surface;GO:0097481//neuronal postsynaptic density;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0005887//integral component of plasma membrane;GO:0060076//excitatory synapse;GO:0043083//synaptic cleft;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0005783//endoplasmic reticulum;GO:0032590//dendrite membrane;GO:0043195//terminal bouton,"GO:0006874//cellular calcium ion homeostasis;GO:0007585//respiratory gaseous exchange;GO:0045471//response to ethanol;GO:0042391//regulation of membrane potential;GO:0006812//cation transport;GO:0035249//synaptic transmission, glutamatergic;GO:0051262//protein tetramerization;GO:0001661//conditioned taste aversion;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0071287//cellular response to manganese ion;GO:0001967//suckling behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043278//response to morphine;GO:0048511//rhythmic process;GO:0001975//response to amphetamine;GO:0021586//pons maturation;GO:0007616//long-term memory;GO:0055074//calcium ion homeostasis;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0051963//regulation of synapse assembly;GO:0043065//positive regulation of apoptotic process;GO:0034220//ion transmembrane transport;GO:0048814//regulation of dendrite morphogenesis;GO:0060179//male mating behavior;GO:0050770//regulation of axonogenesis;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0060134//prepulse inhibition;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0043576//regulation of respiratory gaseous exchange;GO:0008355//olfactory learning;GO:0008542//visual learning;GO:0019233//sensory perception of pain;GO:0043524//negative regulation of neuron apoptotic process;GO:0018964//propylene metabolic process;GO:0008344//adult locomotory behavior;GO:0060992//response to fungicide;GO:0051592//response to calcium ion;GO:0070588//calcium ion transmembrane transport;GO:0021987//cerebral cortex development;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0035176//social behavior",GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005262//calcium channel activity;GO:0046982//protein heterodimerization activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0035254//glutamate receptor binding;GO:0016594//glycine binding;GO:0016595//glutamate binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005516//calmodulin binding;GO:0042165//neurotransmitter binding;GO:0022843//voltage-gated cation channel activity;GO:0019899//enzyme binding,K05208//Cocaine addiction;Huntington's disease;Nicotine addiction;Alcoholism;Calcium signaling pathway;Long-term potentiation;Neuroactive ligand-receptor interaction;Glutamatergic synapse;Amphetamine addiction;Alzheimer's disease;Amyotrophic lateral sclerosis (ALS)
29028,0,26,0,14,55,24,0,0,42,145,0,0,"ATAD2;ATPase family, AAA domain containing 2",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0006200//ATP catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005524//ATP binding;GO:0016887//ATPase activity,K13525//Protein processing in endoplasmic reticulum;Legionellosis
2903,0,0,1,0,5,19,40,0,67,0,5,0,"GRIN2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A",GO:0005887//integral component of plasma membrane;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0008021//synaptic vesicle;GO:0097481//neuronal postsynaptic density;GO:0005783//endoplasmic reticulum,"GO:0009611//response to wounding;GO:0001964//startle response;GO:0007613//memory;GO:0019233//sensory perception of pain;GO:0001975//response to amphetamine;GO:0030431//sleep;GO:0008542//visual learning;GO:0022008//neurogenesis;GO:0042177//negative regulation of protein catabolic process;GO:0007268//synaptic transmission;GO:0043065//positive regulation of apoptotic process;GO:0070588//calcium ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0051930//regulation of sensory perception of pain;GO:0006810//transport;GO:0007611//learning or memory;GO:0033058//directional locomotion;GO:0042428//serotonin metabolic process;GO:0042493//response to drug;GO:0045471//response to ethanol;GO:0008104//protein localization;GO:0007215//glutamate receptor signaling pathway;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0035249//synaptic transmission, glutamatergic;GO:0042417//dopamine metabolic process;GO:0048167//regulation of synaptic plasticity;GO:0060079//regulation of excitatory postsynaptic membrane potential",GO:0005262//calcium channel activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K05209//Nicotine addiction;Cocaine addiction;Dopaminergic synapse;Neuroactive ligand-receptor interaction;Long-term potentiation;Calcium signaling pathway;Alcoholism;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;Systemic lupus erythematosus;Glutamatergic synapse;Amphetamine addiction
29035,0,10,1,1,108,45,42,0,12,103,12,181,C16orf72;chromosome 16 open reading frame 72,-,-,-,-
2904,0,0,45,0,0,0,27,40,0,0,5,0,"GRIN2B;glutamate receptor, ionotropic, N-methyl D-aspartate 2B",GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0043005//neuron projection;GO:0097481//neuronal postsynaptic density;GO:0008021//synaptic vesicle;GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,"GO:0001701//in utero embryonic development;GO:0007611//learning or memory;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0048167//regulation of synaptic plasticity;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0035249//synaptic transmission, glutamatergic;GO:0048266//behavioral response to pain;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0007215//glutamate receptor signaling pathway;GO:0045471//response to ethanol;GO:0007612//learning;GO:0001967//suckling behavior;GO:0007613//memory;GO:0001964//startle response;GO:0001662//behavioral fear response;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0007423//sensory organ development",GO:0005515//protein binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0005262//calcium channel activity;GO:0008270//zinc ion binding;GO:0016594//glycine binding,K05210//Cocaine addiction;Dopaminergic synapse;Huntington's disease;Nicotine addiction;Alcoholism;Long-term potentiation;Neuroactive ligand-receptor interaction;Systemic lupus erythematosus;Amphetamine addiction;Glutamatergic synapse;Alzheimer's disease;Amyotrophic lateral sclerosis (ALS)
2905,281,0,0,0,0,0,38,45,50,0,19,0,"GRIN2C;glutamate receptor, ionotropic, N-methyl D-aspartate 2C",GO:0014069//postsynaptic density;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,"GO:0034220//ion transmembrane transport;GO:0035249//synaptic transmission, glutamatergic;GO:0006810//transport;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0042177//negative regulation of protein catabolic process;GO:0008104//protein localization;GO:0007215//glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:0033058//directional locomotion;GO:0009611//response to wounding",GO:0005515//protein binding;GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005234//extracellular-glutamate-gated ion channel activity;GO:0030165//PDZ domain binding;GO:0005261//cation channel activity;GO:0047485//protein N-terminus binding,K05211//Alzheimer's disease;Amyotrophic lateral sclerosis (ALS);Glutamatergic synapse;Amphetamine addiction;Long-term potentiation;Neuroactive ligand-receptor interaction;Calcium signaling pathway;Alcoholism;Nicotine addiction;Cocaine addiction
29058,90,56,3,41,140,0,40,84,62,0,0,0,TMEM230;transmembrane protein 230,GO:0016021//integral component of membrane,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
2906,84,0,0,0,0,20,0,0,47,0,0,1,"GRIN2D;glutamate receptor, ionotropic, N-methyl D-aspartate 2D",GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex,"GO:0035249//synaptic transmission, glutamatergic;GO:0051930//regulation of sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0008344//adult locomotory behavior;GO:0001964//startle response;GO:0007165//signal transduction",GO:0004972//N-methyl-D-aspartate selective glutamate receptor activity;GO:0005515//protein binding;GO:0005234//extracellular-glutamate-gated ion channel activity,K05212//Cocaine addiction;Nicotine addiction;Alcoholism;Calcium signaling pathway;Neuroactive ligand-receptor interaction;Long-term potentiation;Amphetamine addiction;Glutamatergic synapse;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease
29062,0,0,0,0,0,9,0,87,6,0,2,0,WDR91;WD repeat domain 91,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K12602//RNA degradation;K11447//Transcriptional misregulation in cancer
29063,0,0,1,0,0,0,0,0,55,192,2,0,"ZCCHC4;zinc finger, CCHC domain containing 4",-,GO:0032259//methylation,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity,K03351//Meiosis - yeast;HTLV-I infection;Oocyte meiosis;Cell cycle;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
29066,0,39,1,24,92,0,0,1,19,2,1,0,ZC3H7A;zinc finger CCCH-type containing 7A,GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,K09553//Prion diseases
29068,0,19,0,8,32,0,0,0,42,0,8,257,ZBTB44;zinc finger and BTB domain containing 44,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
2907,0,0,0,0,1,23,9,0,0,0,0,0,"GRINA;glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)",GO:0016021//integral component of membrane,-,-,-
29070,0,40,121,22,35,0,0,56,96,6,12,0,CCDC113;coiled-coil domain containing 113,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
29072,168,72,0,52,155,25,23,1,64,181,11,0,SETD2;SET domain containing 2,GO:0005634//nucleus;GO:0005694//chromosome,"GO:0001763//morphogenesis of a branching structure;GO:0034728//nucleosome organization;GO:0010793//regulation of mRNA export from nucleus;GO:0006298//mismatch repair;GO:0060039//pericardium development;GO:0001843//neural tube closure;GO:0060977//coronary vasculature morphogenesis;GO:0035441//cell migration involved in vasculogenesis;GO:0030900//forebrain development;GO:0048332//mesoderm morphogenesis;GO:0048864//stem cell development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0097198//histone H3-K36 trimethylation;GO:0060669//embryonic placenta morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0001525//angiogenesis",GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity,K11423//Lysine degradation
29074,0,0,1,10,57,0,0,0,19,0,0,0,MRPL18;mitochondrial ribosomal protein L18,GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0005761//mitochondrial ribosome,GO:0006412//translation;GO:0035928//rRNA import into mitochondrion,GO:0003735//structural constituent of ribosome;GO:0008097//5S rRNA binding,-
29078,22,0,0,0,64,0,0,0,0,0,0,0,"NDUFAF4;NADH dehydrogenase (ubiquinone) complex I, assembly factor 4",GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane,GO:0032981//mitochondrial respiratory chain complex I assembly,GO:0005516//calmodulin binding;GO:0005515//protein binding,-
29079,0,36,33,18,33,0,0,0,16,0,0,0,MED4;mediator complex subunit 4,GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus;GO:0016592//mediator complex;GO:0005654//nucleoplasm,"GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway",GO:0003712//transcription cofactor activity;GO:0046966//thyroid hormone receptor binding;GO:0004872//receptor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042809//vitamin D receptor binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity,-
2908,121,41,0,70,74,7,0,0,96,0,0,0,"NR3C1;nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)",GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0030325//adrenal gland development;GO:0031946//regulation of glucocorticoid biosynthetic process;GO:0010467//gene expression;GO:0043525//positive regulation of neuron apoptotic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006111//regulation of gluconeogenesis;GO:0042921//glucocorticoid receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0007165//signal transduction;GO:0043402//glucocorticoid mediated signaling pathway;GO:0008211//glucocorticoid metabolic process;GO:0060603//mammary gland duct morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0005496//steroid binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004883//glucocorticoid receptor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046983//protein dimerization activity,K05771//Neuroactive ligand-receptor interaction
29080,0,0,19,13,31,0,0,0,6,24,57,0,CCDC59;coiled-coil domain containing 59,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
29081,0,195,2,182,203,0,0,0,15,0,94,0,METTL5;methyltransferase like 5,-,GO:0032259//methylation,GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity,-
29082,0,21,0,13,45,0,0,111,25,0,0,0,CHMP4A;charged multivesicular body protein 4A,GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0030496//midbody;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0000815//ESCRT III complex;GO:0070062//extracellular vesicular exosome;GO:0030659//cytoplasmic vesicle membrane;GO:0009898//cytoplasmic side of plasma membrane,GO:0016032//viral process;GO:0051260//protein homooligomerization;GO:0019058//viral life cycle;GO:0006620//posttranslational protein targeting to membrane;GO:0006900//membrane budding;GO:1901215//negative regulation of neuron death;GO:1902902//negative regulation of autophagic vacuole assembly;GO:0097320//membrane tubulation;GO:0016197//endosomal transport;GO:0061024//membrane organization,GO:0008289//lipid binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0051117//ATPase binding,K12194//Endocytosis
29083,0,0,0,28,47,0,0,0,9,0,0,0,GTPBP8;GTP-binding protein 8 (putative),GO:0005739//mitochondrion,GO:0000917//barrier septum assembly,GO:0005525//GTP binding;GO:0046872//metal ion binding,-
29085,0,0,0,17,7,10,27,219,0,0,31,0,PHPT1;phosphohistidine phosphatase 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006470//protein dephosphorylation;GO:0051350//negative regulation of lyase activity;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:2000984//negative regulation of ATP citrate synthase activity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0035971//peptidyl-histidine dephosphorylation;GO:2000147//positive regulation of cell motility;GO:2000249//regulation of actin cytoskeleton reorganization,GO:0019855//calcium channel inhibitor activity;GO:0004721//phosphoprotein phosphatase activity;GO:0008969//phosphohistidine phosphatase activity;GO:0044325//ion channel binding,K01112//Fructose and mannose metabolism
29086,0,0,0,0,49,0,0,1,9,1,8,0,BABAM1;BRISC and BRCA1 A complex member 1,GO:0070552//BRISC complex;GO:0070531//BRCA1-A complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0070536//protein K63-linked deubiquitination;GO:0045739//positive regulation of DNA repair;GO:0010212//response to ionizing radiation;GO:0031572//G2 DNA damage checkpoint;GO:0016568//chromatin modification;GO:0006302//double-strand break repair,GO:0005515//protein binding,-
29087,0,22,0,6,8,19,20,0,0,0,12,0,THYN1;thymocyte nuclear protein 1,GO:0005634//nucleus,-,-,-
29088,0,0,0,4,17,0,0,0,48,0,0,0,MRPL15;mitochondrial ribosomal protein L15,GO:0015934//large ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
29089,0,0,0,0,0,0,0,59,28,0,0,0,UBE2T;ubiquitin-conjugating enzyme E2T (putative),GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0006513//protein monoubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0070979//protein K11-linked ubiquitination;GO:0051865//protein autoubiquitination;GO:0035519//protein K29-linked ubiquitination,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0003682//chromatin binding;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity,K13960//Fanconi anemia pathway
2909,1,91,0,36,158,1,0,0,61,0,8,0,ARHGAP35;Rho GTPase activating protein 35,GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005829//cytosol,"GO:0043116//negative regulation of vascular permeability;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0030900//forebrain development;GO:0007264//small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0001843//neural tube closure;GO:0043010//camera-type eye development",GO:0003677//DNA binding;GO:0005100//Rho GTPase activator activity;GO:0003714//transcription corepressor activity;GO:0005525//GTP binding,K05732//Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Focal adhesion
29090,0,0,0,0,12,0,35,0,12,0,0,0,TIMM21;translocase of inner mitochondrial membrane 21 homolog (yeast),GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0030150//protein import into mitochondrial matrix;GO:0033617//mitochondrial respiratory chain complex IV assembly,GO:0005515//protein binding,-
29091,143,11,1,3,15,0,0,76,43,0,39,509,STXBP6;syntaxin binding protein 6 (amisyn),GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0016192//vesicle-mediated transport;GO:0045920//negative regulation of exocytosis,-,-
29093,0,0,0,0,39,0,0,0,0,263,0,332,MRPL22;mitochondrial ribosomal protein L22,GO:0015934//large ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
29094,105,71,1,71,191,28,0,0,32,0,9,1,"LGALSL;lectin, galactoside-binding-like",GO:0005622//intracellular,-,GO:0030246//carbohydrate binding,-
29095,0,0,22,21,30,2,0,0,33,241,19,0,ORMDL2;ORMDL sphingolipid biosynthesis regulator 2,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0006672//ceramide metabolic process,-,K12667//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
29097,0,0,0,7,0,0,0,0,0,124,0,0,CNIH4;cornichon family AMPA receptor auxiliary protein 4,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0035556//intracellular signal transduction,-,-
29098,0,32,0,3,23,0,21,0,0,0,0,0,RANGRF;RAN guanine nucleotide release factor,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005634//nucleus;GO:0005791//rough endoplasmic reticulum;GO:0005730//nucleolus,GO:1902305//regulation of sodium ion transmembrane transport;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:2000010//positive regulation of protein localization to cell surface;GO:0002027//regulation of heart rate;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:0042391//regulation of membrane potential;GO:0032527//protein exit from endoplasmic reticulum;GO:0003254//regulation of membrane depolarization;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0043547//positive regulation of GTPase activity;GO:0006888//ER to Golgi vesicle-mediated transport,GO:0008536//Ran GTPase binding;GO:0008565//protein transporter activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017080//sodium channel regulator activity;GO:0044325//ion channel binding,-
29099,0,0,0,4,7,0,0,0,11,1,0,0,COMMD9;COMM domain containing 9,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
291,0,1,1,14,60,7,29,0,0,0,0,0,"SLC25A4;solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4",GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0015853//adenine transport;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0008637//apoptotic mitochondrial changes;GO:0000002//mitochondrial genome maintenance;GO:0044281//small molecule metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006810//transport;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0055085//transmembrane transport,GO:0005515//protein binding;GO:0015207//adenine transmembrane transporter activity,K05863//HTLV-I infection;Huntington's disease;Parkinson's disease;Influenza A;Calcium signaling pathway
29100,0,0,0,0,0,0,0,0,7,0,0,0,TMEM208;transmembrane protein 208,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006914//autophagy,-,K04682//Cell cycle;TGF-beta signaling pathway
29101,0,18,1,52,53,0,0,0,6,1,46,0,SSU72;SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006378//mRNA polyadenylation;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain,GO:0005515//protein binding;GO:0008420//CTD phosphatase activity,K15544//mRNA surveillance pathway
29102,54,24,0,1,36,41,12,4,38,0,18,0,"DROSHA;drosha, ribonuclease type III",GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0031053//primary miRNA processing;GO:0010586//miRNA metabolic process;GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0031054//pre-miRNA processing;GO:0050830//defense response to Gram-positive bacterium;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0016075//rRNA catabolic process;GO:0050829//defense response to Gram-negative bacterium",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0001530//lipopolysaccharide binding;GO:0004525//ribonuclease III activity,K03685//Ribosome biogenesis in eukaryotes
29103,0,0,0,0,15,0,0,0,13,0,0,0,"DNAJC15;DnaJ (Hsp40) homolog, subfamily C, member 15",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0019216//regulation of lipid metabolic process;GO:0015031//protein transport;GO:0009267//cellular response to starvation;GO:0031333//negative regulation of protein complex assembly,-,-
29104,0,0,0,0,0,0,10,0,0,0,0,0,N6AMT1;N-6 adenine-specific DNA methyltransferase 1 (putative),GO:0043234//protein complex,GO:0030307//positive regulation of cell growth;GO:0006479//protein methylation,GO:0005515//protein binding;GO:0008276//protein methyltransferase activity;GO:0003676//nucleic acid binding,K00599//Metabolic pathways;Tyrosine metabolism;Microbial metabolism in diverse environments;Histidine metabolism;Lipopolysaccharide biosynthesis;Polycyclic aromatic hydrocarbon degradation
29105,32,0,0,0,10,0,4,19,0,0,0,0,CFAP20;cilia and flagella associated protein 20,GO:0070062//extracellular vesicular exosome;GO:0005814//centriole;GO:0036064//ciliary basal body;GO:0005929//cilium,GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0018095//protein polyglutamylation;GO:2000147//positive regulation of cell motility;GO:0007275//multicellular organismal development;GO:2000253//positive regulation of feeding behavior;GO:0060271//cilium morphogenesis,GO:0044822//poly(A) RNA binding,-
29106,0,0,0,0,0,0,0,0,20,0,0,0,SCG3;secretogranin III,GO:0005576//extracellular region;GO:0030658//transport vesicle membrane;GO:0034774//secretory granule lumen,GO:0030168//platelet activation;GO:0002576//platelet degranulation;GO:0007596//blood coagulation,GO:0044822//poly(A) RNA binding,-
29107,22,0,0,0,0,5,1,0,0,124,0,0,NXT1;nuclear transport factor 2-like export factor 1,GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0016607//nuclear speck,GO:0006405//RNA export from nucleus;GO:0006611//protein export from nucleus,GO:0005515//protein binding;GO:0008536//Ran GTPase binding,K14285//Ribosome biogenesis in eukaryotes;Influenza A;mRNA surveillance pathway;RNA transport
29108,0,0,0,0,20,0,0,0,0,0,2,0,PYCARD;PYD and CARD domain containing,GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0072558//NLRP1 inflammasome complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0072559//NLRP3 inflammasome complex;GO:0008385//IkappaB kinase complex;GO:0097169//AIM2 inflammasome complex,"GO:0045087//innate immune response;GO:0050870//positive regulation of T cell activation;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0002588//positive regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0050829//defense response to Gram-negative bacterium;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0046330//positive regulation of JNK cascade;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0090197//positive regulation of chemokine secretion;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0050766//positive regulation of phagocytosis;GO:2001242//regulation of intrinsic apoptotic signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0071347//cellular response to interleukin-1;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2000406//positive regulation of T cell migration;GO:0032729//positive regulation of interferon-gamma production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0032688//negative regulation of interferon-beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0044351//macropinocytosis;GO:2000484//positive regulation of interleukin-8 secretion;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0031647//regulation of protein stability;GO:0051607//defense response to virus;GO:0032755//positive regulation of interleukin-6 production;GO:0002277//myeloid dendritic cell activation involved in immune response;GO:0006954//inflammatory response;GO:0030838//positive regulation of actin filament polymerization;GO:0002218//activation of innate immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0002821//positive regulation of adaptive immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:2001181//positive regulation of interleukin-10 secretion;GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:2000778//positive regulation of interleukin-6 secretion",GO:0032090//Pyrin domain binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K12799//NOD-like receptor signaling pathway;Influenza A;Legionellosis;Pertussis;Salmonella infection;Cytosolic DNA-sensing pathway
29109,0,0,0,0,3,0,31,0,28,0,0,0,FHOD1;formin homology 2 domain containing 1,GO:0016020//membrane;GO:0032059//bleb;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051496//positive regulation of stress fiber assembly,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0003779//actin binding,K02184//Dorso-ventral axis formation;K05745//Regulation of actin cytoskeleton
2911,0,33,15,0,0,32,47,48,75,0,20,0,"GRM1;glutamate receptor, metabotropic 1",GO:0038038//G-protein coupled receptor homodimeric complex;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0005634//nucleus,"GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0051930//regulation of sensory perception of pain;GO:0000187//activation of MAPK activity;GO:0071257//cellular response to electrical stimulus;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007626//locomotory behavior;GO:0008219//cell death;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0019233//sensory perception of pain",GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding,K04604//Huntington's disease;Long-term depression;Gap junction;Neuroactive ligand-receptor interaction;Long-term potentiation;Retrograde endocannabinoid signaling;Calcium signaling pathway;Glutamatergic synapse
29110,0,0,2,15,86,19,49,0,7,0,0,0,TBK1;TANK-binding kinase 1,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0010008//endosome membrane,GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050830//defense response to Gram-positive bacterium;GO:0006954//inflammatory response;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051607//defense response to virus;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0016032//viral process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0009615//response to virus;GO:0002224//toll-like receptor signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032727//positive regulation of interferon-alpha production;GO:0010629//negative regulation of gene expression;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0004674//protein serine/threonine kinase activity;GO:0003676//nucleic acid binding;GO:0005524//ATP binding,K05410//Cytosolic DNA-sensing pathway;Hepatitis C;Herpes simplex infection;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Measles;Toll-like receptor signaling pathway;Influenza A
29113,0,0,0,0,0,0,0,0,6,0,0,0,C6orf15;chromosome 6 open reading frame 15,GO:0005614//interstitial matrix,GO:0030198//extracellular matrix organization,GO:0043236//laminin binding;GO:0070052//collagen V binding;GO:0001968//fibronectin binding;GO:0008201//heparin binding;GO:0005540//hyaluronic acid binding,-
29114,11,0,0,0,0,13,0,0,9,0,0,0,TAGLN3;transgelin 3,GO:0005634//nucleus,GO:0007417//central nervous system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,-,-
29116,0,0,0,0,77,36,0,0,33,0,0,0,MYLIP;myosin regulatory light chain interacting protein,GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005622//intracellular;GO:0005886//plasma membrane,GO:0045732//positive regulation of protein catabolic process;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0031648//protein destabilization;GO:0032803//regulation of low-density lipoprotein particle receptor catabolic process;GO:0016567//protein ubiquitination;GO:0007399//nervous system development;GO:0006928//cellular component movement;GO:0042632//cholesterol homeostasis,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008092//cytoskeletal protein binding,-
29117,0,17,0,10,46,23,44,1,30,0,0,0,BRD7;bromodomain containing 7,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0035066//positive regulation of histone acetylation;GO:0008285//negative regulation of cell proliferation",GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0008134//transcription factor binding;GO:0003714//transcription corepressor activity;GO:0070577//lysine-acetylated histone binding;GO:0003713//transcription coactivator activity;GO:0002039//p53 binding,-
29118,59,0,0,0,0,0,0,45,31,0,0,0,DDX25;DEAD (Asp-Glu-Ala-Asp) box helicase 25,GO:0033391//chromatoid body;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006417//regulation of translation;GO:0007275//multicellular organismal development;GO:0006200//ATP catabolic process;GO:0007286//spermatid development;GO:0006406//mRNA export from nucleus,GO:0004004//ATP-dependent RNA helicase activity;GO:0003723//RNA binding;GO:0005524//ATP binding,K01529//Purine metabolism;K13025//mRNA surveillance pathway;RNA transport;Spliceosome
29119,1,0,0,0,0,20,36,0,67,258,0,0,"CTNNA3;catenin (cadherin-associated protein), alpha 3",GO:0030027//lamellipodium;GO:0005916//fascia adherens;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton,GO:0016337//single organismal cell-cell adhesion,GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0045296//cadherin binding,K05691//Leukocyte transendothelial migration;Adherens junction;Bacterial invasion of epithelial cells;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Endometrial cancer;Pathways in cancer
2912,0,0,0,0,0,0,0,0,37,0,2,0,"GRM2;glutamate receptor, metabotropic 2",GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0030054//cell junction;GO:0030424//axon,"GO:0014047//glutamate secretion;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007268//synaptic transmission",GO:0005246//calcium channel regulator activity;GO:0001641//group II metabotropic glutamate receptor activity;GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity,K04605//Cocaine addiction;Glutamatergic synapse;Neuroactive ligand-receptor interaction
29121,0,1,0,0,0,27,0,58,32,0,0,0,"CLEC2D;C-type lectin domain family 2, member D",GO:0005887//integral component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0009986//cell surface,GO:0007166//cell surface receptor signaling pathway,GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity,-
29122,0,0,0,0,0,0,0,0,27,0,0,0,"PRSS50;protease, serine, 50",GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum,GO:0006508//proteolysis,GO:0004298//threonine-type endopeptidase activity;GO:0004252//serine-type endopeptidase activity,-
29123,42,35,0,11,22,59,28,0,84,0,20,137,ANKRD11;ankyrin repeat domain 11,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0060348//bone development;GO:0048705//skeletal system morphogenesis;GO:0060325//face morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001894//tissue homeostasis;GO:0035264//multicellular organism growth;GO:0001701//in utero embryonic development,-,-
29124,0,0,0,0,0,0,0,0,16,0,7,0,"LGALS13;lectin, galactoside-binding, soluble, 13",-,GO:0006644//phospholipid metabolic process;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0004622//lysophospholipase activity,-
29125,0,0,0,0,0,2,0,0,16,0,0,0,C11orf21;chromosome 11 open reading frame 21,GO:0005737//cytoplasm,-,-,-
29126,17,0,0,0,0,22,11,0,23,0,6,0,CD274;CD274 molecule,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0012505//endomembrane system;GO:0005886//plasma membrane,GO:0042130//negative regulation of T cell proliferation;GO:2001181//positive regulation of interleukin-10 secretion;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0031295//T cell costimulation;GO:0007165//signal transduction,GO:0005515//protein binding,K06745//Cell adhesion molecules (CAMs)
29127,0,0,0,0,27,0,0,0,30,0,3,0,RACGAP1;Rac GTPase activating protein 1,GO:0032154//cleavage furrow;GO:0051233//spindle midzone;GO:0070062//extracellular vesicular exosome;GO:0072686//mitotic spindle;GO:0097149//centralspindlin complex;GO:0001669//acrosomal vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0030496//midbody;GO:0005874//microtubule;GO:0005634//nucleus,"GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0000915//actomyosin contractile ring assembly;GO:0007108//cytokinesis, initiation of separation;GO:0007283//spermatogenesis;GO:0032467//positive regulation of cytokinesis;GO:0007405//neuroblast proliferation;GO:0008272//sulfate transport;GO:0051256//spindle midzone assembly involved in mitosis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007018//microtubule-based movement;GO:0009790//embryo development;GO:0000281//mitotic cytokinesis;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity","GO:0046872//metal ion binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0005096//GTPase activator activity;GO:0019901//protein kinase binding;GO:0008017//microtubule binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043015//gamma-tubulin binding",K04450//Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;Alcoholism;Influenza A
29128,0,0,0,0,0,1,5,30,56,0,19,0,UHRF1;ubiquitin-like with PHD and ring finger domains 1,GO:0000791//euchromatin;GO:0005657//replication fork;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005720//nuclear heterochromatin,"GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0007049//cell cycle;GO:0010216//maintenance of DNA methylation;GO:0032270//positive regulation of cellular protein metabolic process;GO:0006281//DNA repair;GO:0016574//histone ubiquitination;GO:0051865//protein autoubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0010390//histone monoubiquitination;GO:0008283//cell proliferation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0008327//methyl-CpG binding;GO:0042802//identical protein binding;GO:0044729//hemi-methylated DNA-binding;GO:0016874//ligase activity;GO:0031493//nucleosomal histone binding;GO:0035064//methylated histone binding;GO:0000987//core promoter proximal region sequence-specific DNA binding,-
2913,0,0,10,0,10,16,13,0,20,0,0,0,"GRM3;glutamate receptor, metabotropic 3",GO:0014069//postsynaptic density;GO:0043197//dendritic spine;GO:0097449//astrocyte projection;GO:0045211//postsynaptic membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0030424//axon,"GO:0007194//negative regulation of adenylate cyclase activity;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007268//synaptic transmission;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway",GO:0001641//group II metabotropic glutamate receptor activity;GO:0005246//calcium channel regulator activity;GO:0004930//G-protein coupled receptor activity;GO:0008066//glutamate receptor activity;GO:0001642//group III metabotropic glutamate receptor activity,K04605//Neuroactive ligand-receptor interaction;Glutamatergic synapse;Cocaine addiction
2914,106,0,0,0,0,34,31,2,13,0,27,0,"GRM4;glutamate receptor, metabotropic 4",GO:0005622//intracellular;GO:0043195//terminal bouton;GO:0005887//integral component of plasma membrane;GO:0048787//presynaptic active zone membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0031410//cytoplasmic vesicle,"GO:0043410//positive regulation of MAPK cascade;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0000187//activation of MAPK activity;GO:0043523//regulation of neuron apoptotic process;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0007612//learning;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway",GO:0001642//group III metabotropic glutamate receptor activity;GO:0048306//calcium-dependent protein binding;GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005516//calmodulin binding,K04607//Taste transduction;Glutamatergic synapse;Neuroactive ligand-receptor interaction
2915,0,0,0,0,0,17,22,0,77,0,8,0,"GRM5;glutamate receptor, metabotropic 5",GO:0097449//astrocyte projection;GO:0043198//dendritic shaft;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0014069//postsynaptic density;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,"GO:0007206//phospholipase C-activating G-protein coupled glutamate receptor signaling pathway;GO:0040013//negative regulation of locomotion;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0007612//learning;GO:0002029//desensitization of G-protein coupled receptor protein signaling pathway;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0050890//cognition;GO:0006355//regulation of transcription, DNA-templated;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007626//locomotory behavior;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0000185//activation of MAPKKK activity",GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0031687//A2A adenosine receptor binding,K04604//Calcium signaling pathway;Retrograde endocannabinoid signaling;Long-term potentiation;Neuroactive ligand-receptor interaction;Gap junction;Long-term depression;Huntington's disease;Glutamatergic synapse
2916,174,0,0,9,10,14,0,0,75,71,14,0,"GRM6;glutamate receptor, metabotropic 6",GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0000139//Golgi membrane;GO:0035841//new growing cell tip;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0090280//positive regulation of calcium ion import;GO:0050908//detection of light stimulus involved in visual perception;GO:0007268//synaptic transmission;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0009584//detection of visible light;GO:0060041//retina development in camera-type eye;GO:0007626//locomotory behavior;GO:0051966//regulation of synaptic transmission, glutamatergic",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0001642//group III metabotropic glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0008066//glutamate receptor activity,K04608//Neuroactive ligand-receptor interaction;Glutamatergic synapse
2917,0,0,0,0,0,25,0,0,11,0,0,0,"GRM7;glutamate receptor, metabotropic 7",GO:0005938//cell cortex;GO:0043198//dendritic shaft;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane;GO:0048786//presynaptic active zone;GO:0043235//receptor complex;GO:0032279//asymmetric synapse;GO:0030424//axon,"GO:0070588//calcium ion transmembrane transport;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007268//synaptic transmission;GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0014050//negative regulation of glutamate secretion;GO:0019226//transmission of nerve impulse;GO:0030534//adult behavior;GO:0007614//short-term memory;GO:0007608//sensory perception of smell;GO:0001661//conditioned taste aversion;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0001662//behavioral fear response;GO:0007605//sensory perception of sound;GO:0030818//negative regulation of cAMP biosynthetic process",GO:0010855//adenylate cyclase inhibitor activity;GO:0030165//PDZ domain binding;GO:0005509//calcium ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0001642//group III metabotropic glutamate receptor activity;GO:0005246//calcium channel regulator activity;GO:0008066//glutamate receptor activity;GO:0016595//glutamate binding;GO:0070905//serine binding,K04608//Neuroactive ligand-receptor interaction;Glutamatergic synapse
2918,26,0,0,0,0,1,23,0,38,0,0,0,"GRM8;glutamate receptor, metabotropic 8",GO:0005887//integral component of plasma membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane,"GO:0007196//adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007601//visual perception;GO:0007608//sensory perception of smell;GO:0030818//negative regulation of cAMP biosynthetic process",GO:0008066//glutamate receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0001642//group III metabotropic glutamate receptor activity,K04608//Glutamatergic synapse;Neuroactive ligand-receptor interaction
2919,0,0,0,0,1,15,9,0,0,0,13,0,"CXCL1;chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0035556//intracellular signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007399//nervous system development;GO:0006955//immune response;GO:0008283//cell proliferation;GO:0006935//chemotaxis;GO:0043085//positive regulation of catalytic activity;GO:0030036//actin cytoskeleton organization;GO:0007165//signal transduction;GO:0060326//cell chemotaxis;GO:0006954//inflammatory response,GO:0008083//growth factor activity;GO:0008009//chemokine activity;GO:0008047//enzyme activator activity;GO:0005102//receptor binding,K05505//NOD-like receptor signaling pathway;Legionellosis;Salmonella infection;NF-kappa B signaling pathway;Rheumatoid arthritis;Chemokine signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Amoebiasis;Cytokine-cytokine receptor interaction
292,30,29,2,10,46,0,0,0,0,0,11,0,"SLC25A5;solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5",GO:0005743//mitochondrial inner membrane;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0071817//MMXD complex,GO:0007059//chromosome segregation;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0055085//transmembrane transport;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0006810//transport;GO:0044281//small molecule metabolic process;GO:0016032//viral process;GO:0008284//positive regulation of cell proliferation;GO:0015853//adenine transport,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0015207//adenine transmembrane transporter activity,K05863//Influenza A;Calcium signaling pathway;Huntington's disease;HTLV-I infection;Parkinson's disease
2920,0,0,0,0,0,0,0,0,0,0,6,0,CXCL2;chemokine (C-X-C motif) ligand 2,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0002237//response to molecule of bacterial origin;GO:0060326//cell chemotaxis;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006954//inflammatory response,GO:0005515//protein binding;GO:0008009//chemokine activity,K05505//Cytokine-cytokine receptor interaction;Epithelial cell signaling in Helicobacter pylori infection;Amoebiasis;Rheumatoid arthritis;NF-kappa B signaling pathway;Salmonella infection;Chemokine signaling pathway;NOD-like receptor signaling pathway;Legionellosis
2921,0,0,0,0,0,23,0,0,28,0,0,0,CXCL3;chemokine (C-X-C motif) ligand 3,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0006954//inflammatory response;GO:0006955//immune response;GO:0030593//neutrophil chemotaxis,GO:0008009//chemokine activity,K05505//Amoebiasis;Epithelial cell signaling in Helicobacter pylori infection;Cytokine-cytokine receptor interaction;Legionellosis;NOD-like receptor signaling pathway;Chemokine signaling pathway;Rheumatoid arthritis;NF-kappa B signaling pathway;Salmonella infection
2922,0,0,0,0,0,0,0,0,7,0,0,0,GRP;gastrin-releasing peptide,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0007218//neuropeptide signaling pathway,GO:0005184//neuropeptide hormone activity;GO:0005102//receptor binding,-
2923,0,0,1,20,79,0,0,0,3,0,7,0,"PDIA3;protein disulfide isomerase family A, member 3",GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0009986//cell surface;GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen,"GO:0045454//cell redox homeostasis;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006621//protein retention in ER lumen;GO:0006457//protein folding;GO:0007165//signal transduction;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0034976//response to endoplasmic reticulum stress;GO:0006606//protein import into nucleus;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",GO:0004629//phospholipase C activity;GO:0044822//poly(A) RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K08056//Protein processing in endoplasmic reticulum;Antigen processing and presentation
2925,110,0,0,0,0,0,0,0,18,0,3,0,GRPR;gastrin-releasing peptide receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0042127//regulation of cell proliferation;GO:0008283//cell proliferation;GO:0031989//bombesin receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004946//bombesin receptor activity;GO:0008528//G-protein coupled peptide receptor activity,K04169//Calcium signaling pathway;Neuroactive ligand-receptor interaction
2926,35,61,1,63,78,0,38,0,29,0,8,0,GRSF1;G-rich RNA sequence binding factor 1,GO:0005737//cytoplasm;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion,GO:0006378//mRNA polyadenylation;GO:0008033//tRNA processing;GO:0016331//morphogenesis of embryonic epithelium;GO:0009952//anterior/posterior pattern specification,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding;GO:0003723//RNA binding,-
293,0,1,1,0,21,21,2,33,6,0,0,0,"SLC25A6;solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6",GO:0005744//mitochondrial inner membrane presequence translocase complex;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0016032//viral process;GO:0046732//active induction of host immune response by virus;GO:0015866//ADP transport;GO:0044281//small molecule metabolic process;GO:0019058//viral life cycle;GO:0050796//regulation of insulin secretion;GO:0006915//apoptotic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0006112//energy reserve metabolic process;GO:0006626//protein targeting to mitochondrion;GO:0015867//ATP transport;GO:0055085//transmembrane transport;GO:0044267//cellular protein metabolic process,GO:0005471//ATP:ADP antiporter activity;GO:0005515//protein binding,K05863//Influenza A;Calcium signaling pathway;Parkinson's disease;HTLV-I infection;Huntington's disease
2931,0,37,0,33,12,0,10,50,33,137,12,0,GSK3A;glycogen synthase kinase 3 alpha,GO:0030877//beta-catenin destruction complex;GO:0005829//cytosol,GO:0032007//negative regulation of TOR signaling;GO:2000077//negative regulation of type B pancreatic cell development;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0044267//cellular protein metabolic process;GO:0006468//protein phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007399//nervous system development;GO:0005977//glycogen metabolic process;GO:0046325//negative regulation of glucose import;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0036016//cellular response to interleukin-3;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0051348//negative regulation of transferase activity;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:0006349//regulation of gene expression by genetic imprinting;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0003073//regulation of systemic arterial blood pressure;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0044027//hypermethylation of CpG island;GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008286//insulin receptor signaling pathway;GO:0045823//positive regulation of heart contraction;GO:0003214//cardiac left ventricle morphogenesis;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0010905//negative regulation of UDP-glucose catabolic process;GO:0016477//cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0071879//positive regulation of adrenergic receptor signaling pathway;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0071285//cellular response to lithium ion;GO:0071407//cellular response to organic cyclic compound;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0045087//innate immune response;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development,GO:0034236//protein kinase A catalytic subunit binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0050321//tau-protein kinase activity;GO:0005524//ATP binding,K08822//Dopaminergic synapse;Chemokine signaling pathway
2932,0,65,1,107,163,1,0,0,1,1,0,0,GSK3B;glycogen synthase kinase 3 beta,GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030877//beta-catenin destruction complex;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0030529//ribonucleoprotein complex;GO:0045121//membrane raft;GO:0005813//centrosome;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0043197//dendritic spine,GO:0007411//axon guidance;GO:0032886//regulation of microtubule-based process;GO:0060070//canonical Wnt signaling pathway;GO:0036016//cellular response to interleukin-3;GO:0032855//positive regulation of Rac GTPase activity;GO:0001837//epithelial to mesenchymal transition;GO:0045732//positive regulation of protein catabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010977//negative regulation of neuron projection development;GO:0031334//positive regulation of protein complex assembly;GO:0030010//establishment of cell polarity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006349//regulation of gene expression by genetic imprinting;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:0042493//response to drug;GO:0005977//glycogen metabolic process;GO:0071260//cellular response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:2000077//negative regulation of type B pancreatic cell development;GO:0043407//negative regulation of MAP kinase activity;GO:0014043//negative regulation of neuron maturation;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0018105//peptidyl-serine phosphorylation;GO:0006983//ER overload response;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000738//positive regulation of stem cell differentiation;GO:0000320//re-entry into mitotic cell cycle;GO:0032091//negative regulation of protein binding;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0009887//organ morphogenesis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0001954//positive regulation of cell-matrix adhesion;GO:0031333//negative regulation of protein complex assembly;GO:0032092//positive regulation of protein binding;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0071109//superior temporal gyrus development;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0021766//hippocampus development;GO:0035372//protein localization to microtubule;GO:0010226//response to lithium ion;GO:0044337//canonical Wnt signaling pathway involved in positive regulation of apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0048168//regulation of neuronal synaptic plasticity;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0045087//innate immune response;GO:0007623//circadian rhythm;GO:0006611//protein export from nucleus;GO:0007520//myoblast fusion;GO:0044027//hypermethylation of CpG island;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0050774//negative regulation of dendrite morphogenesis;GO:0046827//positive regulation of protein export from nucleus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016477//cell migration,GO:0035255//ionotropic glutamate receptor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0048156//tau protein binding;GO:0050321//tau-protein kinase activity;GO:0002039//p53 binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0019901//protein kinase binding;GO:0051059//NF-kappaB binding;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0008013//beta-catenin binding,K03083//Insulin signaling pathway;Pathways in cancer;Chemokine signaling pathway;Dopaminergic synapse;Axon guidance;Influenza A;Prostate cancer;Basal cell carcinoma;Wnt signaling pathway;Circadian rhythm - fly;Hedgehog signaling pathway;T cell receptor signaling pathway;Colorectal cancer;Epstein-Barr virus infection;Cell cycle;ErbB signaling pathway;HTLV-I infection;B cell receptor signaling pathway;Hepatitis C;Neurotrophin signaling pathway;Alzheimer's disease;Endometrial cancer;Melanogenesis;Focal adhesion;Measles;K04617//Neuroactive ligand-receptor interaction
2934,0,0,1,0,3,0,6,0,16,0,17,0,GSN;gelsolin,GO:0048471//perinuclear region of cytoplasm;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0043234//protein complex;GO:0030027//lamellipodium;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0001726//ruffle,GO:0045471//response to ethanol;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006915//apoptotic process;GO:0051016//barbed-end actin filament capping;GO:0071276//cellular response to cadmium ion;GO:0030155//regulation of cell adhesion;GO:0030041//actin filament polymerization;GO:0051014//actin filament severing;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0060271//cilium morphogenesis;GO:0016192//vesicle-mediated transport;GO:0014003//oligodendrocyte development;GO:0051593//response to folic acid;GO:0007568//aging;GO:0042246//tissue regeneration,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0003779//actin binding,K05768//Fc gamma R-mediated phagocytosis;Regulation of actin cytoskeleton
2935,0,29,3,103,245,26,0,105,38,0,4,350,GSPT1;G1 to S phase transition 1,GO:0005622//intracellular,"GO:0006184//GTP catabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006479//protein methylation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination",GO:0003747//translation release factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K03267//mRNA surveillance pathway
2936,30,67,2,60,323,0,0,0,24,0,3,0,GSR;glutathione reductase,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005829//cytosol,GO:0006749//glutathione metabolic process;GO:0055114//oxidation-reduction process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0044281//small molecule metabolic process;GO:0045454//cell redox homeostasis,GO:0009055//electron carrier activity;GO:0004362//glutathione-disulfide reductase activity;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding,K00383//Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Glutathione metabolism;Biosynthesis of secondary metabolites
2937,0,27,0,6,115,0,0,0,2,0,0,0,GSS;glutathione synthetase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0007399//nervous system development;GO:0006979//response to oxidative stress;GO:0006520//cellular amino acid metabolic process;GO:0031667//response to nutrient levels;GO:0046686//response to cadmium ion;GO:0043200//response to amino acid;GO:0034612//response to tumor necrosis factor;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0006750//glutathione biosynthetic process;GO:0007568//aging,GO:0005524//ATP binding;GO:0004363//glutathione synthase activity;GO:0016594//glycine binding;GO:0043295//glutathione binding;GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity,K01920//Metabolic pathways;Glutathione metabolism
2938,0,0,0,0,6,1,5,0,8,0,0,0,GSTA1;glutathione S-transferase alpha 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006749//glutathione metabolic process;GO:0044281//small molecule metabolic process;GO:0008152//metabolic process;GO:0006805//xenobiotic metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0030855//epithelial cell differentiation,GO:0004364//glutathione transferase activity,K00799//Prostate cancer;Glutathione metabolism;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
2939,0,0,0,0,0,22,0,0,22,0,0,132,GSTA2;glutathione S-transferase alpha 2,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006749//glutathione metabolic process;GO:0030855//epithelial cell differentiation;GO:1901687//glutathione derivative biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0004364//glutathione transferase activity,K00799//Drug metabolism - cytochrome P450;Pathways in cancer;Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism
2940,0,0,0,0,0,0,17,0,7,0,0,0,GSTA3;glutathione S-transferase alpha 3,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:1901687//glutathione derivative biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006749//glutathione metabolic process,GO:0004364//glutathione transferase activity,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
2941,0,2,0,0,69,0,10,0,14,0,3,0,GSTA4;glutathione S-transferase alpha 4,GO:0005829//cytosol,GO:0006749//glutathione metabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:1901687//glutathione derivative biosynthetic process,GO:0004364//glutathione transferase activity;GO:0042803//protein homodimerization activity,K00799//Drug metabolism - cytochrome P450;Pathways in cancer;Metabolism of xenobiotics by cytochrome P450;Glutathione metabolism;Prostate cancer
2946,0,0,0,0,20,12,36,44,1,0,13,0,GSTM2;glutathione S-transferase mu 2 (muscle),GO:0016529//sarcoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0018916//nitrobenzene metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0006805//xenobiotic metabolic process;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0044281//small molecule metabolic process;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0070458//cellular detoxification of nitrogen compound;GO:0042178//xenobiotic catabolic process;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0055119//relaxation of cardiac muscle;GO:0006749//glutathione metabolic process;GO:0071313//cellular response to caffeine;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity,GO:0042803//protein homodimerization activity;GO:0043295//glutathione binding;GO:0005102//receptor binding;GO:0019899//enzyme binding;GO:0004364//glutathione transferase activity,K00799//Glutathione metabolism;Prostate cancer;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
2947,67,1,1,24,22,9,0,66,38,0,14,0,GSTM3;glutathione S-transferase mu 3 (brain),GO:0070062//extracellular vesicular exosome;GO:0035686//sperm fibrous sheath;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006749//glutathione metabolic process;GO:0043627//response to estrogen;GO:0008065//establishment of blood-nerve barrier;GO:0042178//xenobiotic catabolic process;GO:0070458//cellular detoxification of nitrogen compound;GO:1901687//glutathione derivative biosynthetic process;GO:0018916//nitrobenzene metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0004364//glutathione transferase activity;GO:0019899//enzyme binding;GO:0043295//glutathione binding,K00799//Pathways in cancer;Drug metabolism - cytochrome P450;Glutathione metabolism;Prostate cancer;Metabolism of xenobiotics by cytochrome P450
2948,0,0,0,0,0,6,18,60,6,0,2,0,GSTM4;glutathione S-transferase mu 4,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006749//glutathione metabolic process;GO:0042178//xenobiotic catabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0043295//glutathione binding;GO:0019899//enzyme binding;GO:0004364//glutathione transferase activity;GO:0042803//protein homodimerization activity,K00799//Drug metabolism - cytochrome P450;Pathways in cancer;Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism
2949,25,0,0,0,10,12,3,81,0,0,0,0,GSTM5;glutathione S-transferase mu 5,GO:0005829//cytosol,GO:0006749//glutathione metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:1901687//glutathione derivative biosynthetic process,GO:0004364//glutathione transferase activity,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
2950,0,1,0,0,15,0,16,0,0,0,0,0,GSTP1;glutathione S-transferase pi 1,GO:0097057//TRAF2-GSTP1 complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005634//nucleus,GO:0009890//negative regulation of biosynthetic process;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0048147//negative regulation of fibroblast proliferation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0043407//negative regulation of MAP kinase activity;GO:0035726//common myeloid progenitor cell proliferation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006749//glutathione metabolic process;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0071222//cellular response to lipopolysaccharide;GO:0070664//negative regulation of leukocyte proliferation;GO:0043409//negative regulation of MAPK cascade;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0002674//negative regulation of acute inflammatory response;GO:0032930//positive regulation of superoxide anion generation;GO:0043508//negative regulation of JUN kinase activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0006805//xenobiotic metabolic process;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0044281//small molecule metabolic process;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0000302//response to reactive oxygen species;GO:1901687//glutathione derivative biosynthetic process;GO:0006469//negative regulation of protein kinase activity;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035732//nitric oxide storage,GO:0004364//glutathione transferase activity;GO:0070026//nitric oxide binding;GO:0035731//dinitrosyl-iron complex binding;GO:0008432//JUN kinase binding;GO:0005515//protein binding;GO:0035730//S-nitrosoglutathione binding;GO:0019207//kinase regulator activity,K00799//Prostate cancer;Glutathione metabolism;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
2954,0,0,0,0,13,0,49,0,33,0,47,0,GSTZ1;glutathione S-transferase zeta 1,GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0055114//oxidation-reduction process;GO:0006749//glutathione metabolic process;GO:0006572//tyrosine catabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0006559//L-phenylalanine catabolic process,GO:0004364//glutathione transferase activity;GO:0016034//maleylacetoacetate isomerase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004602//glutathione peroxidase activity,K01800//Pyrimidine metabolism;Microbial metabolism in diverse environments;Tyrosine metabolism;Metabolic pathways;Styrene degradation
2956,5,17,0,44,115,9,68,0,71,1,41,0,MSH6;mutS homolog 6,GO:0005737//cytoplasm;GO:0032301//MutSalpha complex;GO:0000228//nuclear chromosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0008340//determination of adult lifespan;GO:0007131//reciprocal meiotic recombination;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0051096//positive regulation of helicase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043570//maintenance of DNA repeat elements;GO:0009411//response to UV;GO:0000710//meiotic mismatch repair;GO:0006281//DNA repair;GO:0045190//isotype switching;GO:0006200//ATP catabolic process;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0006298//mismatch repair;GO:0045910//negative regulation of DNA recombination,GO:0000400//four-way junction DNA binding;GO:0035064//methylated histone binding;GO:0032142//single guanine insertion binding;GO:0032357//oxidized purine DNA binding;GO:0030983//mismatched DNA binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0043531//ADP binding;GO:0016887//ATPase activity;GO:0032143//single thymine insertion binding;GO:0032137//guanine/thymine mispair binding;GO:0042803//protein homodimerization activity;GO:0032405//MutLalpha complex binding;GO:0000287//magnesium ion binding;GO:0003690//double-stranded DNA binding;GO:0008094//DNA-dependent ATPase activity,K08737//Mismatch repair;Colorectal cancer;Pathways in cancer
2957,0,12,32,30,62,10,10,44,54,0,0,0,"GTF2A1;general transcription factor IIA, 1, 19/37kDa",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005672//transcription factor TFIIA complex;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0017025//TBP-class protein binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding,K03122//Basal transcription factors
2958,0,0,0,0,32,0,0,0,13,0,0,0,"GTF2A2;general transcription factor IIA, 2, 12kDa",GO:0005672//transcription factor TFIIA complex;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process,GO:0003713//transcription coactivator activity;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0017025//TBP-class protein binding;GO:0008134//transcription factor binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K03123//Basal transcription factors
2959,0,0,0,0,10,0,1,0,20,0,0,0,GTF2B;general transcription factor IIB,GO:0005654//nucleoplasm,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression",GO:0017025//TBP-class protein binding;GO:0046966//thyroid hormone receptor binding;GO:0001047//core promoter binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding,K03124//Basal transcription factors;Epstein-Barr virus infection
2960,0,0,0,14,38,0,0,0,13,0,0,109,"GTF2E1;general transcription factor IIE, polypeptide 1, alpha 56kDa",GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,K03136//Basal transcription factors;Epstein-Barr virus infection
2961,0,0,0,0,86,0,25,0,0,224,6,0,"GTF2E2;general transcription factor IIE, polypeptide 2, beta 34kDa",GO:0005673//transcription factor TFIIE complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K03137//Basal transcription factors;Epstein-Barr virus infection
2962,23,0,0,0,15,15,47,25,2,0,0,0,"GTF2F1;general transcription factor IIF, polypeptide 1, 74kDa",GO:0030054//cell junction;GO:0005634//nucleus;GO:0005674//transcription factor TFIIF complex;GO:0005654//nucleoplasm,"GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0043085//positive regulation of catalytic activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0009615//response to virus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0006370//7-methylguanosine mRNA capping",GO:0003824//catalytic activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0019211//phosphatase activator activity,K03138//Basal transcription factors
2963,0,0,47,0,29,0,0,0,25,0,0,315,"GTF2F2;general transcription factor IIF, polypeptide 2, 30kDa",GO:0005634//nucleus;GO:0005674//transcription factor TFIIF complex;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006370//7-methylguanosine mRNA capping;GO:0006200//ATP catabolic process;GO:0050434//positive regulation of viral transcription;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process",GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0005524//ATP binding,K03139//Basal transcription factors
2965,0,0,0,51,82,0,0,0,51,0,61,0,"GTF2H1;general transcription factor IIH, polypeptide 1, 62kDa",GO:0005730//nucleolus;GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0000439//core TFIIH complex;GO:0005654//nucleoplasm,"GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006468//protein phosphorylation;GO:0006283//transcription-coupled nucleotide-excision repair",GO:0008094//DNA-dependent ATPase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,K03141//Nucleotide excision repair;Basal transcription factors
2966,2,0,0,0,0,0,0,0,8,0,0,280,"GTF2H2;general transcription factor IIH, polypeptide 2, 44kDa",GO:0005675//holo TFIIH complex;GO:0005654//nucleoplasm;GO:0000439//core TFIIH complex,"GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006468//protein phosphorylation;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0002031//G-protein coupled receptor internalization;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0009411//response to UV;GO:0006412//translation;GO:0010467//gene expression","GO:0008135//translation factor activity, nucleic acid binding;GO:0004672//protein kinase activity;GO:0047485//protein N-terminus binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008094//DNA-dependent ATPase activity;GO:0003676//nucleic acid binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity",K03142//Nucleotide excision repair;Basal transcription factors
2967,94,0,0,12,0,16,55,0,26,0,0,0,"GTF2H3;general transcription factor IIH, polypeptide 3, 34kDa",GO:0005675//holo TFIIH complex;GO:0005654//nucleoplasm;GO:0000439//core TFIIH complex,"GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006468//protein phosphorylation;GO:0016032//viral process;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0050434//positive regulation of viral transcription;GO:0006200//ATP catabolic process;GO:0006412//translation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0006355//regulation of transcription, DNA-templated;GO:0006362//transcription elongation from RNA polymerase I promoter","GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0003684//damaged DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0004672//protein kinase activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0047485//protein N-terminus binding",K03143//Nucleotide excision repair;Basal transcription factors
2968,0,0,0,0,0,1,1,4,0,0,0,0,"GTF2H4;general transcription factor IIH, polypeptide 4, 52kDa",GO:0000439//core TFIIH complex;GO:0005654//nucleoplasm;GO:0005675//holo TFIIH complex,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006468//protein phosphorylation;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006200//ATP catabolic process;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0016032//viral process;GO:0032508//DNA duplex unwinding;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006368//transcription elongation from RNA polymerase II promoter",GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0004003//ATP-dependent DNA helicase activity;GO:0008094//DNA-dependent ATPase activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004672//protein kinase activity,K03144//Nucleotide excision repair;Basal transcription factors
2969,47,54,0,28,206,0,0,1,35,0,0,0,GTF2I;general transcription factor IIi,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane,"GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0016525//negative regulation of angiogenesis;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K03121//Basal transcription factors;Herpes simplex infection
2971,0,33,2,83,140,0,0,5,0,0,27,0,GTF3A;general transcription factor IIIA,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0009303//rRNA transcription;GO:0006383//transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
2972,0,265,260,154,267,0,19,1116,164,0,596,14,"BRF1;BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit",GO:0000126//transcription factor TFIIIB complex;GO:0005654//nucleoplasm,"GO:0009304//tRNA transcription;GO:0010467//gene expression;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0009303//rRNA transcription;GO:0043488//regulation of mRNA stability;GO:0006383//transcription from RNA polymerase III promoter",GO:0008270//zinc ion binding;GO:0017025//TBP-class protein binding,-
2974,0,0,0,0,0,2,0,0,27,0,5,0,"GUCY1B2;guanylate cyclase 1, soluble, beta 2 (pseudogene)",-,-,-,K12319//Gap junction;Long-term depression;Vascular smooth muscle contraction;Purine metabolism;Salivary secretion
2975,84,82,1,20,86,35,63,0,40,0,10,0,"GTF3C1;general transcription factor IIIC, polypeptide 1, alpha 220kDa",GO:0005654//nucleoplasm;GO:0000127//transcription factor TFIIIC complex;GO:0005634//nucleus;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,"GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0009304//tRNA transcription;GO:0006383//transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0009303//rRNA transcription;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding,-
2976,0,12,0,12,9,0,0,42,13,0,18,0,"GTF3C2;general transcription factor IIIC, polypeptide 2, beta 110kDa",GO:0005654//nucleoplasm;GO:0000127//transcription factor TFIIIC complex,"GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0006383//transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
29760,9,0,0,0,10,17,0,0,7,0,5,0,BLNK;B-cell linker,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005829//cytosol,GO:0030183//B cell differentiation;GO:0006954//inflammatory response;GO:0006959//humoral immune response;GO:0009967//positive regulation of signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035556//intracellular signal transduction,GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07371//Osteoclast differentiation;Primary immunodeficiency;NF-kappa B signaling pathway;B cell receptor signaling pathway
29761,10,0,0,0,49,28,36,20,46,129,0,0,USP25;ubiquitin specific peptidase 25,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006464//cellular protein modification process;GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0008233//peptidase activity;GO:0032183//SUMO binding,-
29763,0,0,0,0,15,0,21,0,4,0,0,0,PACSIN3;protein kinase C and casein kinase substrate in neurons 3,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0051926//negative regulation of calcium ion transport;GO:0006897//endocytosis;GO:0097320//membrane tubulation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0045806//negative regulation of endocytosis,GO:0005515//protein binding;GO:0008289//lipid binding;GO:0008092//cytoskeletal protein binding;GO:0019855//calcium channel inhibitor activity,K10408//Huntington's disease;K12804//NOD-like receptor signaling pathway
29765,0,1,0,0,0,0,1,68,2,0,0,1,TMOD4;tropomodulin 4 (muscle),GO:0005865//striated muscle thin filament,GO:0006936//muscle contraction,GO:0005523//tropomyosin binding;GO:0003779//actin binding,-
29766,0,25,0,35,107,0,27,15,25,0,9,0,TMOD3;tropomodulin 3 (ubiquitous),GO:0005865//striated muscle thin filament,-,GO:0003779//actin binding;GO:0005523//tropomyosin binding,-
29767,102,0,0,12,27,18,70,0,40,0,3,1,TMOD2;tropomodulin 2 (neuronal),GO:0005856//cytoskeleton;GO:0030426//growth cone;GO:0005737//cytoplasm,GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0007611//learning or memory;GO:0007399//nervous system development;GO:0007270//neuron-neuron synaptic transmission,GO:0005523//tropomyosin binding;GO:0003779//actin binding,-
2977,0,0,0,9,0,0,16,76,93,0,0,0,"GUCY1A2;guanylate cyclase 1, soluble, alpha 2",GO:0005737//cytoplasm,GO:0007596//blood coagulation;GO:0006182//cGMP biosynthetic process;GO:0035556//intracellular signal transduction;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0007165//signal transduction,GO:0004383//guanylate cyclase activity;GO:0020037//heme binding;GO:0005525//GTP binding,K12318//Long-term depression;Vascular smooth muscle contraction;Gap junction;Purine metabolism;Salivary secretion
29774,0,0,0,0,0,0,0,0,12,0,0,0,"POM121L9P;POM121 transmembrane nucleoporin-like 9, pseudogene",-,-,-,K14316//RNA transport
29775,1,0,0,0,0,0,14,45,15,0,12,0,"CARD10;caspase recruitment domain family, member 10",GO:0005737//cytoplasm;GO:0032449//CBM complex,GO:0042981//regulation of apoptotic process;GO:0006461//protein complex assembly;GO:0007250//activation of NF-kappaB-inducing kinase activity,GO:0030159//receptor signaling complex scaffold activity;GO:0005515//protein binding,K07367//B cell receptor signaling pathway;T cell receptor signaling pathway;NF-kappa B signaling pathway
29777,0,0,0,2,0,25,0,0,0,0,0,0,ABT1;activator of basal transcription 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0021522//spinal cord motor neuron differentiation,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,-
2978,0,0,24,2,0,23,0,6,17,0,0,0,GUCA1A;guanylate cyclase activator 1A (retina),GO:0097381//photoreceptor disc membrane;GO:0001917//photoreceptor inner segment;GO:0005886//plasma membrane,"GO:0007601//visual perception;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0007165//signal transduction;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007603//phototransduction, visible light",GO:0005509//calcium ion binding;GO:0008048//calcium sensitive guanylate cyclase activator activity,K08328//Phototransduction;Olfactory transduction
29780,85,0,19,1,1,0,0,8,20,91,3,0,"PARVB;parvin, beta",GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0030018//Z disc;GO:0005856//cytoskeleton,GO:0007155//cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0071963//establishment or maintenance of cell polarity regulating cell shape;GO:0030032//lamellipodium assembly;GO:0034329//cell junction assembly;GO:0030031//cell projection assembly,GO:0005515//protein binding;GO:0003779//actin binding,K06275//Focal adhesion
29781,0,46,1,61,77,1,0,129,69,0,208,0,"NCAPH2;non-SMC condensin II complex, subunit H2",GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0005694//chromosome,GO:0000278//mitotic cell cycle;GO:0030261//chromosome condensation,GO:0005515//protein binding,-
29785,0,0,0,0,0,17,2,0,60,0,16,0,"CYP2S1;cytochrome P450, family 2, subfamily S, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0020037//heme binding,K07420//Metabolism of xenobiotics by cytochrome P450
29789,0,0,1,71,126,0,27,0,105,0,0,0,OLA1;Obg-like ATPase 1,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0043023//ribosomal large subunit binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0043022//ribosome binding;GO:0005525//GTP binding,-
2979,14,0,0,0,0,11,0,0,14,1,0,0,GUCA1B;guanylate cyclase activator 1B (retina),GO:0097381//photoreceptor disc membrane;GO:0001917//photoreceptor inner segment,"GO:0007267//cell-cell signaling;GO:0007589//body fluid secretion;GO:0007601//visual perception;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007603//phototransduction, visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway",GO:0008048//calcium sensitive guanylate cyclase activator activity;GO:0005509//calcium ion binding,K08328//Phototransduction;Olfactory transduction
29796,0,0,0,12,8,0,0,0,0,0,0,0,"UQCR10;ubiquinol-cytochrome c reductase, complex III subunit X",GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c",GO:0008121//ubiquinol-cytochrome-c reductase activity,K00419//Cardiac muscle contraction;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
29797,2,29,44,16,47,5,4,67,40,6,36,2,POM121L8P;POM121 transmembrane nucleoporin-like 8 pseudogene,-,-,-,K08878//Pathways in cancer;Chronic myeloid leukemia
29798,3,0,0,0,0,0,0,0,0,0,0,0,C2orf27A;chromosome 2 open reading frame 27A,-,-,-,-
29799,0,105,20,36,209,0,0,0,38,109,248,0,YPEL1;yippee-like 1 (Drosophila),GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
29800,0,0,0,0,0,0,26,0,27,0,7,0,"ZDHHC1;zinc finger, DHHC-type containing 1",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
29801,94,0,0,0,0,0,0,0,18,0,1,0,"ZDHHC8;zinc finger, DHHC-type containing 8",GO:0005794//Golgi apparatus;GO:0030659//cytoplasmic vesicle membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0018345//protein palmitoylation;GO:0007626//locomotory behavior,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding,K05766//Regulation of actin cytoskeleton;K13911//Salivary secretion
29802,0,16,0,0,0,0,0,1,0,0,0,0,VPREB3;pre-B lymphocyte 3,GO:0005783//endoplasmic reticulum,-,-,-
29803,0,78,1,6,15,9,17,0,22,135,0,0,REPIN1;replication initiator 1,GO:0005664//nuclear origin of replication recognition complex;GO:0005811//lipid particle;GO:0005634//nucleus;GO:0022626//cytosolic ribosome;GO:0031965//nuclear membrane,GO:2001273//regulation of glucose import in response to insulin stimulus;GO:0006260//DNA replication;GO:2000191//regulation of fatty acid transport,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
2981,0,0,0,0,0,0,0,0,9,0,0,0,GUCA2B;guanylate cyclase activator 2B (uroguanylin),GO:0070062//extracellular vesicular exosome,GO:0006182//cGMP biosynthetic process;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007589//body fluid secretion;GO:0007588//excretion;GO:0045776//negative regulation of blood pressure,GO:0008048//calcium sensitive guanylate cyclase activator activity,-
2982,0,99,0,49,220,0,0,0,35,8,0,0,"GUCY1A3;guanylate cyclase 1, soluble, alpha 3","GO:0008074//guanylate cyclase complex, soluble",GO:0006182//cGMP biosynthetic process;GO:0052565//response to defense-related host nitric oxide production;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0007596//blood coagulation;GO:0060087//relaxation of vascular smooth muscle;GO:0007263//nitric oxide mediated signal transduction,GO:0004383//guanylate cyclase activity;GO:0004872//receptor activity;GO:0005525//GTP binding;GO:0020037//heme binding,K12318//Purine metabolism;Salivary secretion;Gap junction;Long-term depression;Vascular smooth muscle contraction
2983,0,0,0,0,7,20,21,0,52,1,1,1,"GUCY1B3;guanylate cyclase 1, soluble, beta 3","GO:0008074//guanylate cyclase complex, soluble;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle",GO:0007596//blood coagulation;GO:0006182//cGMP biosynthetic process;GO:0007263//nitric oxide mediated signal transduction;GO:0008015//blood circulation,GO:0004872//receptor activity;GO:0005525//GTP binding;GO:0020037//heme binding;GO:0046982//protein heterodimerization activity;GO:0051879//Hsp90 protein binding;GO:0004383//guanylate cyclase activity;GO:0046872//metal ion binding,K12319//Salivary secretion;Purine metabolism;Vascular smooth muscle contraction;Long-term depression;Gap junction
2984,108,126,1,173,193,12,28,0,55,0,67,58,GUCY2C;guanylate cyclase 2C (heat stable enterotoxin receptor),GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0009636//response to toxic substance;GO:0006468//protein phosphorylation;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0035556//intracellular signal transduction;GO:0006182//cGMP biosynthetic process;GO:0042127//regulation of cell proliferation,GO:0015643//toxic substance binding;GO:0004383//guanylate cyclase activity;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0005525//GTP binding,K12320//Purine metabolism
29841,0,0,0,24,52,0,6,0,137,0,7,0,GRHL1;grainyhead-like 1 (Drosophila),GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0044255//cellular lipid metabolic process;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
29842,0,21,2,31,39,16,31,0,24,0,0,0,TFCP2L1;transcription factor CP2-like 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,"GO:0007431//salivary gland development;GO:0007565//female pregnancy;GO:0045927//positive regulation of growth;GO:0006694//steroid biosynthetic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007028//cytoplasm organization;GO:0000902//cell morphogenesis;GO:0006351//transcription, DNA-templated;GO:0008340//determination of adult lifespan;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002070//epithelial cell maturation",GO:0003714//transcription corepressor activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
29843,0,0,0,13,40,26,0,3,16,0,8,0,SENP1;SUMO1/sentrin specific peptidase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005925//focal adhesion,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043687//post-translational protein modification;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010724//regulation of definitive erythrocyte differentiation;GO:0006508//proteolysis;GO:0097190//apoptotic signaling pathway;GO:0044267//cellular protein metabolic process;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016926//protein desumoylation;GO:0016925//protein sumoylation,GO:0004175//endopeptidase activity;GO:0016929//SUMO-specific protease activity;GO:0005515//protein binding,-
29844,151,0,0,4,1,14,0,0,14,0,0,0,TFPT;TCF3 (E2A) fusion partner (in childhood Leukemia),GO:0005884//actin filament;GO:0005634//nucleus;GO:0031011//Ino80 complex;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0097190//apoptotic signaling pathway;GO:0006281//DNA repair;GO:0043065//positive regulation of apoptotic process;GO:0006310//DNA recombination",GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,-
29850,0,0,0,0,0,22,51,0,74,0,7,0,"TRPM5;transient receptor potential cation channel, subfamily M, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005227//calcium activated cation channel activity;GO:0005272//sodium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0005216//ion channel activity;GO:0005267//potassium channel activity,K04980//Taste transduction
29851,0,0,0,0,0,0,0,0,5,0,0,0,ICOS;inducible T-cell co-stimulator,GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0006955//immune response;GO:0031295//T cell costimulation;GO:0002517//T cell tolerance induction;GO:0016337//single organismal cell-cell adhesion,-,K06713//Intestinal immune network for IgA production;Cell adhesion molecules (CAMs);Primary immunodeficiency;T cell receptor signaling pathway
29855,0,68,2,41,140,0,42,1,43,0,84,0,UBN1;ubinuclein 1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005923//tight junction;GO:0016605//PML body,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0016032//viral process;GO:0010923//negative regulation of phosphatase activity;GO:0006336//DNA replication-independent nucleosome assembly,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
2986,0,0,0,0,0,16,16,68,0,0,7,0,"GUCY2F;guanylate cyclase 2F, retinal",GO:0005887//integral component of plasma membrane;GO:0097381//photoreceptor disc membrane;GO:0005640//nuclear outer membrane,"GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0007603//phototransduction, visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007601//visual perception;GO:0006182//cGMP biosynthetic process",GO:0004383//guanylate cyclase activity;GO:0004672//protein kinase activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0004872//receptor activity,K12321//Purine metabolism;Olfactory transduction;Phototransduction
2987,0,25,0,7,2,0,14,1,0,0,1,0,GUK1;guanylate kinase 1,GO:0005829//cytosol,GO:0046939//nucleotide phosphorylation;GO:0006163//purine nucleotide metabolic process;GO:0046037//GMP metabolic process;GO:0044281//small molecule metabolic process;GO:0046711//GDP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0034436//glycoprotein transport;GO:0019673//GDP-mannose metabolic process;GO:0046034//ATP metabolic process;GO:0046060//dATP metabolic process;GO:0006185//dGDP biosynthetic process;GO:0046054//dGMP metabolic process;GO:0017144//drug metabolic process,GO:0004385//guanylate kinase activity;GO:0005524//ATP binding,K00942//Purine metabolism;Metabolic pathways
29880,0,0,0,0,1,0,0,0,14,0,0,0,"ALG5;ALG5, dolichyl-phosphate beta-glucosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007368//determination of left/right symmetry;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006486//protein glycosylation,GO:0004581//dolichyl-phosphate beta-glucosyltransferase activity;GO:0004576//oligosaccharyl transferase activity,K00729//Metabolic pathways;N-Glycan biosynthesis
29881,0,0,0,0,0,0,0,0,87,0,2,0,NPC1L1;NPC1-like 1,GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0016324//apical plasma membrane,GO:0042157//lipoprotein metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0030301//cholesterol transport;GO:0030299//intestinal cholesterol absorption,GO:0008158//hedgehog receptor activity;GO:0008144//drug binding;GO:0017137//Rab GTPase binding;GO:0031489//myosin V binding;GO:0005515//protein binding,K14461//Fat digestion and absorption
29882,0,15,41,19,7,0,0,1,8,0,46,0,ANAPC2;anaphase promoting complex subunit 2,GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0031915//positive regulation of synaptic plasticity;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0045773//positive regulation of axon extension;GO:0090129//positive regulation of synapse maturation;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0050775//positive regulation of dendrite morphogenesis;GO:0070979//protein K11-linked ubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division,GO:0031625//ubiquitin protein ligase binding,K03349//Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle;Oocyte meiosis;HTLV-I infection;Meiosis - yeast
29883,0,8,1,26,204,14,0,0,30,0,0,0,"CNOT7;CCR4-NOT transcription complex, subunit 7",GO:0005829//cytosol;GO:0016020//membrane;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex,"GO:0035195//gene silencing by miRNA;GO:0008284//positive regulation of cell proliferation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0031047//gene silencing by RNA;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0006417//regulation of translation;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0006351//transcription, DNA-templated;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0007165//signal transduction;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0005975//carbohydrate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000290//deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening",GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0004871//signal transducer activity;GO:0004535//poly(A)-specific ribonuclease activity;GO:0004532//exoribonuclease activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K12581//RNA degradation
29886,63,0,0,0,0,7,26,0,17,0,1,8,SNX8;sorting nexin 8,GO:0031901//early endosome membrane;GO:0030904//retromer complex,GO:0034498//early endosome to Golgi transport;GO:0006886//intracellular protein transport,GO:0035091//phosphatidylinositol binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
29887,0,0,33,0,0,10,0,68,41,1,0,0,SNX10;sorting nexin 10,GO:0005634//nucleus;GO:0005813//centrosome;GO:0031313//extrinsic component of endosome membrane;GO:0005783//endoplasmic reticulum,GO:0061512//protein localization to cilium;GO:0071539//protein localization to centrosome;GO:0030316//osteoclast differentiation;GO:0042384//cilium assembly;GO:0007032//endosome organization;GO:0006886//intracellular protein transport,GO:0051117//ATPase binding;GO:0005545//1-phosphatidylinositol binding,-
29888,0,0,1,3,1,3,79,5,33,0,17,96,"STRN4;striatin, calmodulin binding protein 4",GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000159//protein phosphatase type 2A complex;GO:0043197//dendritic spine,-,GO:0051721//protein phosphatase 2A binding;GO:0005516//calmodulin binding;GO:0070016//armadillo repeat domain binding;GO:0032403//protein complex binding;GO:0005515//protein binding,-
29889,0,15,0,9,38,18,19,0,28,0,0,0,GNL2;guanine nucleotide binding protein-like 2 (nucleolar),GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus,GO:0042254//ribosome biogenesis;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0044822//poly(A) RNA binding,K14537//Ribosome biogenesis in eukaryotes
29890,0,79,248,104,71,40,52,336,180,124,74,229,RBM15B;RNA binding motif protein 15B,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0016032//viral process;GO:0006351//transcription, DNA-templated;GO:0006913//nucleocytoplasmic transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003723//RNA binding,-
29893,0,219,190,147,215,0,0,0,25,0,96,0,PSMC3IP;PSMC3 interacting protein,GO:0005634//nucleus,GO:0007126//meiotic nuclear division;GO:0006310//DNA recombination;GO:2001141//regulation of RNA biosynthetic process,GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003677//DNA binding,-
29894,0,0,1,12,10,0,15,3,40,1,13,0,"CPSF1;cleavage and polyadenylation specific factor 1, 160kDa",GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex,"GO:0006406//mRNA export from nucleus;GO:0006379//mRNA cleavage;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006378//mRNA polyadenylation;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0005515//protein binding;GO:0003730//mRNA 3'-UTR binding,K14401//mRNA surveillance pathway
29895,0,0,8,0,0,0,0,0,15,0,0,0,"MYLPF;myosin light chain, phosphorylatable, fast skeletal muscle",GO:0005765//lysosomal membrane;GO:0005859//muscle myosin complex,GO:0006955//immune response;GO:0007519//skeletal muscle tissue development,GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle,K12758//Leukocyte transendothelial migration;Focal adhesion;Regulation of actin cytoskeleton;Tight junction
29896,0,0,1,18,21,0,0,8,18,0,8,0,TRA2A;transformer 2 alpha homolog (Drosophila),GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,"GO:0000398//mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K12897//Spliceosome
29899,0,0,0,0,0,11,14,0,38,0,2,0,GPSM2;G-protein signaling modulator 2,GO:0005730//nucleolus;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045177//apical part of cell,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0000132//establishment of mitotic spindle orientation;GO:0060487//lung epithelial cell differentiation,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0030695//GTPase regulator activity,-
2990,0,0,0,0,8,2,0,0,15,0,0,0,"GUSB;glucuronidase, beta",GO:0043202//lysosomal lumen;GO:0070062//extracellular vesicular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane,GO:0005975//carbohydrate metabolic process;GO:0030214//hyaluronan catabolic process;GO:0044281//small molecule metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030212//hyaluronan metabolic process,GO:0004566//beta-glucuronidase activity,K01195//Drug metabolism - other enzymes;Lysosome;Starch and sucrose metabolism;Pentose and glucuronate interconversions;Metabolic pathways;Glycosaminoglycan degradation;Porphyrin and chlorophyll metabolism
29901,0,0,0,0,0,1,2,0,48,0,0,0,SAC3D1;SAC3 domain containing 1,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005819//spindle,GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
29902,0,0,0,0,8,0,0,42,34,2,0,0,"FAM216A;family with sequence similarity 216, member A",-,-,-,-
29903,0,1,44,0,5,0,0,125,19,0,1,0,CCDC106;coiled-coil domain containing 106,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,-
29904,53,0,0,7,42,20,43,101,36,0,0,0,EEF2K;eukaryotic elongation factor-2 kinase,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0046777//protein autophosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0031952//regulation of protein autophosphorylation;GO:0006414//translational elongation,"GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004686//elongation factor-2 kinase activity;GO:0005509//calcium ion binding;GO:0004672//protein kinase activity;GO:0008135//translation factor activity, nucleic acid binding",-
29906,0,0,0,0,0,35,0,0,10,0,13,0,"ST8SIA5;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5",GO:0030173//integral component of Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0097503//sialylation,"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373//sialyltransferase activity",K03369//Glycosphingolipid biosynthesis - ganglio series;Metabolic pathways
29909,58,0,0,0,0,0,0,0,0,97,0,0,GPR171;G protein-coupled receptor 171,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
29911,1,0,0,1,1,3,1,1,25,1,1,1,HOOK2;hook microtubule-tethering protein 2,GO:0070695//FHF complex;GO:0005874//microtubule;GO:0030897//HOPS complex;GO:0005813//centrosome,GO:0045022//early endosome to late endosome transport;GO:0006897//endocytosis;GO:0008333//endosome to lysosome transport;GO:0007040//lysosome organization;GO:0015031//protein transport;GO:0007032//endosome organization,GO:0005515//protein binding;GO:0042802//identical protein binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K06267//ECM-receptor interaction;K10873//Homologous recombination
29914,0,0,0,0,31,0,0,0,0,67,0,0,UBIAD1;UbiA prenyltransferase domain containing 1,GO:0030173//integral component of Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0006744//ubiquinone biosynthetic process;GO:0009234//menaquinone biosynthetic process;GO:0042371//vitamin K biosynthetic process,GO:0004659//prenyltransferase activity;GO:0016209//antioxidant activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
29915,0,0,0,6,22,0,0,0,31,0,5,0,HCFC2;host cell factor C2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0016032//viral process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003713//transcription coactivator activity,K14966//Herpes simplex infection
29916,0,0,0,5,19,0,0,0,30,81,0,0,SNX11;sorting nexin 11,GO:0016020//membrane;GO:0005768//endosome,GO:0006886//intracellular protein transport;GO:0016050//vesicle organization,GO:1901981//phosphatidylinositol phosphate binding,K08545//MAPK signaling pathway - fly
29919,0,0,0,11,25,19,21,0,27,0,0,0,C18orf8;chromosome 18 open reading frame 8,GO:0005765//lysosomal membrane,-,-,-
2992,0,47,0,11,88,0,0,0,32,0,1,0,GYG1;glycogenin 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0005978//glycogen biosynthetic process;GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,GO:0008466//glycogenin glucosyltransferase activity;GO:0005536//glucose binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
29920,0,0,1,6,16,0,31,0,0,0,12,0,"PYCR2;pyrroline-5-carboxylate reductase family, member 2",GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process;GO:0055129//L-proline biosynthetic process,GO:0004735//pyrroline-5-carboxylate reductase activity,"K00286//Arginine and proline metabolism;Metabolic pathways;Propanoate metabolism;Pyruvate metabolism;Two-component system;Glycine, serine and threonine metabolism;Methane metabolism;Biosynthesis of secondary metabolites;Taurine and hypotaurine metabolism;Microbial metabolism in diverse environments"
29922,0,0,0,3,6,33,1,0,2,0,0,0,NME7;NME/NM23 family member 7,GO:0036064//ciliary basal body;GO:0005813//centrosome,GO:0006183//GTP biosynthetic process;GO:0007420//brain development;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway;GO:0006241//CTP biosynthetic process;GO:0060972//left/right pattern formation;GO:0006228//UTP biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0042073//intraciliary transport;GO:0007368//determination of left/right symmetry;GO:0003351//epithelial cilium movement,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity,K00940//Bacterial invasion of epithelial cells;Metabolic pathways;Nitrogen metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Shigellosis;Purine metabolism
29924,41,1,0,4,7,0,0,52,2,106,18,0,EPN1;epsin 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005905//coated pit;GO:0005886//plasma membrane,GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0001701//in utero embryonic development;GO:0007565//female pregnancy;GO:0048568//embryonic organ development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006897//endocytosis,GO:0008289//lipid binding;GO:0008134//transcription factor binding,K12471//Endocytosis
29925,52,23,0,11,7,36,0,1,0,0,0,0,GMPPB;GDP-mannose pyrophosphorylase B,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0009298//GDP-mannose biosynthetic process;GO:0043687//post-translational protein modification;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0004475//mannose-1-phosphate guanylyltransferase activity;GO:0005525//GTP binding,K00966//Fructose and mannose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
29926,0,0,0,12,11,0,0,119,4,1,0,1,GMPPA;GDP-mannose pyrophosphorylase A,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0009298//GDP-mannose biosynthetic process,GO:0016779//nucleotidyltransferase activity,K00966//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Fructose and mannose metabolism;Metabolic pathways
29927,0,16,2,34,21,0,0,0,32,0,0,0,SEC61A1;Sec61 alpha 1 subunit (S. cerevisiae),GO:0016020//membrane;GO:0005791//rough endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane,"GO:0034341//response to interferon-gamma;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0007029//endoplasmic reticulum organization;GO:0006620//posttranslational protein targeting to membrane;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016049//cell growth;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",GO:0005515//protein binding;GO:0043022//ribosome binding,K10956//Protein processing in endoplasmic reticulum;Phagosome;Protein export;Vibrio cholerae infection
29928,0,0,0,0,24,0,0,0,4,0,0,0,TIMM22;translocase of inner mitochondrial membrane 22 homolog (yeast),GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process;GO:0045039//protein import into mitochondrial inner membrane,GO:0015266//protein channel activity,-
29929,0,0,0,0,0,0,0,0,21,0,0,105,"ALG6;ALG6, alpha-1,3-glucosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0043687//post-translational protein modification;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0046527//glucosyltransferase activity,K03848//Metabolic pathways;N-Glycan biosynthesis
2993,0,0,0,0,0,17,0,0,0,0,0,0,GYPA;glycophorin A (MNS blood group),GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0009615//response to virus;GO:0047484//regulation of response to osmotic stress;GO:0016032//viral process;GO:0007016//cytoskeletal anchoring at plasma membrane,GO:0001618//virus receptor activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity,K06575//Hematopoietic cell lineage;Malaria
29930,0,1,0,0,0,0,0,0,21,0,0,0,PCDHB1;protocadherin beta 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
29933,0,0,0,0,0,0,0,55,9,0,5,0,GPR132;G protein-coupled receptor 132,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006950//response to stress;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle,GO:0004930//G-protein coupled receptor activity,-
29934,0,2,1,1,16,24,2,0,26,0,2,0,SNX12;sorting nexin 12,GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005768//endosome;GO:0016020//membrane,GO:0006886//intracellular protein transport;GO:0042177//negative regulation of protein catabolic process;GO:0030100//regulation of endocytosis;GO:0051224//negative regulation of protein transport;GO:0010955//negative regulation of protein processing;GO:0010629//negative regulation of gene expression,GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0019899//enzyme binding,K08545//MAPK signaling pathway - fly
29935,0,0,0,0,0,0,0,0,35,0,0,0,"RPA4;replication protein A4, 30kDa",GO:0005662//DNA replication factor A complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0000077//DNA damage checkpoint;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0006289//nucleotide-excision repair;GO:0006310//DNA recombination;GO:0000278//mitotic cell cycle;GO:0033260//nuclear cell cycle DNA replication,GO:0003697//single-stranded DNA binding,K10741//DNA replication;Nucleotide excision repair;Homologous recombination;Mismatch repair;Fanconi anemia pathway
29937,3,0,0,8,4,0,0,0,0,0,0,0,NENF;neudesin neurotrophic factor,GO:0005615//extracellular space,GO:0043410//positive regulation of MAPK cascade,GO:0046872//metal ion binding;GO:0008083//growth factor activity;GO:0020037//heme binding,-
29940,0,0,0,0,0,22,0,0,23,0,0,0,DSE;dermatan sulfate epimerase,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,GO:0047757//chondroitin-glucuronate 5-epimerase activity,K01794//Glycosaminoglycan biosynthesis - chondroitin sulfate
29941,63,24,0,30,0,46,10,0,1,0,20,0,PKN3;protein kinase N3,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus,GO:0010631//epithelial cell migration;GO:0007165//signal transduction;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004697//protein kinase C activity;GO:0005524//ATP binding,K06071//Salmonella infection
29942,0,0,0,0,0,0,0,0,44,0,0,0,PURG;purine-rich element binding protein G,GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
29943,0,0,39,0,0,0,86,0,13,115,0,0,"PADI1;peptidyl arginine deiminase, type I",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0018101//protein citrullination,GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding,-
29944,0,0,0,0,0,0,23,53,11,0,0,0,PNMA3;paraneoplastic Ma antigen 3,GO:0005730//nucleolus,GO:0043065//positive regulation of apoptotic process,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption
29945,0,0,0,0,38,16,39,23,24,9,0,0,ANAPC4;anaphase promoting complex subunit 4,GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0019903//protein phosphatase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K03351//Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;Meiosis - yeast;HTLV-I infection;Oocyte meiosis
29946,0,0,0,0,11,0,0,0,0,0,0,0,SERTAD3;SERTA domain containing 3,GO:0005634//nucleus,"GO:0030308//negative regulation of cell growth;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
29947,0,0,0,0,0,19,3,0,1,0,0,0,DNMT3L;DNA (cytosine-5-)-methyltransferase 3-like,GO:0005720//nuclear heterochromatin;GO:0000794//condensed nuclear chromosome;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0007283//spermatogenesis;GO:0001890//placenta development;GO:0060718//chorionic trophoblast cell differentiation;GO:0043085//positive regulation of catalytic activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006306//DNA methylation;GO:0001701//in utero embryonic development;GO:0006349//regulation of gene expression by genetic imprinting",GO:0008047//enzyme activator activity;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K00558//Folate biosynthesis;Cysteine and methionine metabolism;Metabolic pathways
29948,0,0,0,0,0,1,0,0,18,0,0,0,OSGIN1;oxidative stress induced growth inhibitor 1,-,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0043065//positive regulation of apoptotic process;GO:0030308//negative regulation of cell growth,GO:0008083//growth factor activity,-
29949,0,0,0,0,0,8,35,0,13,0,23,0,IL19;interleukin 19,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006955//immune response;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0042226//interleukin-6 biosynthetic process;GO:0007165//signal transduction;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0072593//reactive oxygen species metabolic process,GO:0005125//cytokine activity,K05444//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
2995,0,0,0,0,0,0,0,0,10,0,0,0,GYPC;glycophorin C (Gerbich blood group),GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0005886//plasma membrane,-,GO:0005515//protein binding,K06576//Malaria
29950,0,0,0,0,0,0,0,0,14,0,0,0,SERTAD1;SERTA domain containing 1,-,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0008284//positive regulation of cell proliferation",GO:0005515//protein binding,-
29951,0,0,0,0,0,0,25,0,43,0,0,0,PDZRN4;PDZ domain containing ring finger 4,-,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity,-
29952,0,0,0,0,0,0,0,53,3,0,0,0,DPP7;dipeptidyl-peptidase 7,GO:0070062//extracellular vesicular exosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005829//cytosol;GO:0005764//lysosome,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity,-
29953,0,0,0,0,0,49,0,0,40,0,0,0,TRHDE;thyrotropin-releasing hormone degrading enzyme,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis;GO:0007165//signal transduction;GO:0007267//cell-cell signaling,GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
29954,82,0,0,6,0,56,0,0,72,0,24,0,POMT2;protein-O-mannosyltransferase 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0035269//protein O-linked mannosylation,GO:0046872//metal ion binding;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity,K00728//Other types of O-glycan biosynthesis
29956,50,17,0,14,72,12,8,0,6,0,11,0,CERS2;ceramide synthase 2,GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process,GO:0050291//sphingosine N-acyltransferase activity;GO:0003677//DNA binding;GO:0005515//protein binding,K04710//Sphingolipid metabolism;Metabolic pathways
29957,0,2,1,39,37,11,16,0,54,0,30,0,"SLC25A24;solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24",GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0010941//regulation of cell death;GO:0006839//mitochondrial transport;GO:0015867//ATP transport;GO:0071277//cellular response to calcium ion;GO:0034599//cellular response to oxidative stress;GO:0055085//transmembrane transport,GO:0005509//calcium ion binding;GO:0005347//ATP transmembrane transporter activity,-
29958,0,0,0,0,0,54,47,0,30,0,11,0,DMGDH;dimethylglycine dehydrogenase,GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0006579//amino-acid betaine catabolic process;GO:0006546//glycine catabolic process;GO:0019695//choline metabolic process;GO:0006544//glycine metabolic process;GO:0032259//methylation,GO:0009055//electron carrier activity;GO:0044822//poly(A) RNA binding;GO:0004047//aminomethyltransferase activity;GO:0047865//dimethylglycine dehydrogenase activity,"K00315//Metabolic pathways;Glycine, serine and threonine metabolism"
29959,0,0,0,7,107,39,23,58,1,0,0,0,NRBP1;nuclear receptor binding protein 1,GO:0012505//endomembrane system;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0005654//nucleoplasm,GO:0010467//gene expression;GO:0006468//protein phosphorylation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006367//transcription initiation from RNA polymerase II promoter,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding,-
2996,0,0,0,0,0,0,0,0,4,0,0,0,GYPE;glycophorin E (MNS blood group),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,-,-,K06575//Malaria;Hematopoietic cell lineage
29960,0,0,0,1,19,8,0,0,6,0,17,0,FTSJ2;FtsJ RNA methyltransferase homolog 2 (E. coli),GO:0005739//mitochondrion;GO:0005730//nucleolus,GO:0031167//rRNA methylation;GO:0008283//cell proliferation;GO:0006364//rRNA processing,GO:0008650//rRNA (uridine-2'-O-)-methyltransferase activity,-
29964,0,0,0,1,0,0,6,0,2,0,0,0,PRICKLE4;prickle homolog 4 (Drosophila),GO:0005634//nucleus,-,GO:0008270//zinc ion binding,K04511//Wnt signaling pathway
29965,0,138,0,13,53,0,8,92,8,0,41,0,CDIP1;cell death-inducing p53 target 1,GO:0005634//nucleus,GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0006915//apoptotic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,-,-
29966,0,0,0,7,137,0,0,0,48,0,0,0,"STRN3;striatin, calmodulin binding protein 3",GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005634//nucleus;GO:0000159//protein phosphatase type 2A complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0032355//response to estradiol",GO:0051721//protein phosphatase 2A binding;GO:0032403//protein complex binding;GO:0070016//armadillo repeat domain binding;GO:0005516//calmodulin binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
29967,0,50,64,47,81,14,30,57,67,0,69,0,LRP12;low density lipoprotein receptor-related protein 12,GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane;GO:0005905//coated pit,GO:0007165//signal transduction;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0040008//regulation of growth,GO:0005515//protein binding;GO:0005041//low-density lipoprotein receptor activity,K06233//Hedgehog signaling pathway
29968,0,37,0,11,75,25,25,0,0,0,14,0,PSAT1;phosphoserine aminotransferase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0008652//cellular amino acid biosynthetic process;GO:0008615//pyridoxine biosynthetic process;GO:0006564//L-serine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0004648//O-phospho-L-serine:2-oxoglutarate aminotransferase activity;GO:0030170//pyridoxal phosphate binding,"K00831//Methane metabolism;Glycine, serine and threonine metabolism;Metabolic pathways;Tyrosine metabolism;Vitamin B6 metabolism;Microbial metabolism in diverse environments"
29969,98,0,0,22,25,0,0,40,8,10,0,0,MDFIC;MyoD family inhibitor domain containing,GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007257//activation of JUN kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0042308//negative regulation of protein import into nucleus;GO:0050434//positive regulation of viral transcription;GO:0016032//viral process;GO:0030111//regulation of Wnt signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated",GO:0030332//cyclin binding;GO:0030957//Tat protein binding;GO:0005515//protein binding;GO:0008134//transcription factor binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer
2997,23,0,1,0,38,54,18,0,25,0,13,0,GYS1;glycogen synthase 1 (muscle),GO:0016020//membrane;GO:0016234//inclusion body;GO:0005829//cytosol,GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0007507//heart development;GO:0005975//carbohydrate metabolic process,"GO:0005536//glucose binding;GO:0019901//protein kinase binding;GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate;GO:0005515//protein binding;GO:0004373//glycogen (starch) synthase activity",K00693//Insulin signaling pathway;Starch and sucrose metabolism
29974,169,0,0,0,0,0,8,0,31,0,0,0,A1CF;APOBEC1 complementation factor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum,GO:0016556//mRNA modification;GO:0010467//gene expression;GO:0050821//protein stabilization;GO:0016554//cytidine to uridine editing;GO:0006397//mRNA processing,GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
29978,0,0,0,1,4,9,0,0,8,0,0,0,UBQLN2;ubiquilin 2,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008219//cell death,GO:0005515//protein binding,K04523//Protein processing in endoplasmic reticulum
29979,0,1,1,90,175,0,0,0,54,0,0,0,UBQLN1;ubiquilin 1,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0000502//proteasome complex;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum,GO:0034976//response to endoplasmic reticulum stress;GO:0071456//cellular response to hypoxia;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0031396//regulation of protein ubiquitination,GO:0005515//protein binding;GO:0019900//kinase binding;GO:0019904//protein domain specific binding,K04523//Protein processing in endoplasmic reticulum
2998,0,0,0,0,0,58,42,0,23,0,0,0,GYS2;glycogen synthase 2 (liver),GO:0005829//cytosol;GO:0043265//ectoplasm;GO:0030864//cortical actin cytoskeleton;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005737//cytoplasm,GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0009749//response to glucose;GO:0006091//generation of precursor metabolites and energy;GO:0005975//carbohydrate metabolic process,"GO:0061547//glycogen synthase activity, transferring glucose-1-phosphate;GO:0042803//protein homodimerization activity;GO:0004373//glycogen (starch) synthase activity",K00693//Insulin signaling pathway;Starch and sucrose metabolism
29980,61,0,0,0,9,0,49,0,9,0,3,6,DONSON;downstream neighbor of SON,GO:0005634//nucleus,GO:0007275//multicellular organismal development,-,-
29982,0,2,0,0,6,0,0,0,22,0,8,0,NRBF2;nuclear receptor binding factor 2,GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter",-,-
29985,90,0,0,0,0,0,28,0,2,0,0,0,"SLC39A3;solute carrier family 39 (zinc transporter), member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0071577//zinc ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity,-
29986,0,0,0,10,0,0,0,0,29,0,0,0,"SLC39A2;solute carrier family 39 (zinc transporter), member 2",GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005887//integral component of plasma membrane,GO:0071577//zinc ion transmembrane transport;GO:0006829//zinc ion transport;GO:0055085//transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity,-
29988,71,0,0,0,0,34,0,0,55,159,13,0,"SLC2A8;solute carrier family 2 (facilitated glucose transporter), member 8",GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0008021//synaptic vesicle;GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane,GO:0007141//male meiosis I;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0001666//response to hypoxia;GO:0005975//carbohydrate metabolic process;GO:0015758//glucose transport,GO:0005355//glucose transmembrane transporter activity;GO:0005536//glucose binding,-
2999,0,0,0,0,0,19,0,0,23,0,0,0,"GZMH;granzyme H (cathepsin G-like 2, protein h-CCPX)",GO:0016020//membrane,GO:0019835//cytolysis;GO:0006915//apoptotic process;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01353//Graft-versus-host disease;Natural killer cell mediated cytotoxicity;Autoimmune thyroid disease;Allograft rejection;Transcriptional misregulation in cancer;Type I diabetes mellitus
29991,0,0,0,0,0,0,0,0,24,0,0,0,OBP2A;odorant binding protein 2A,GO:0005576//extracellular region,GO:0050896//response to stimulus;GO:0006810//transport;GO:0007606//sensory perception of chemical stimulus;GO:0007608//sensory perception of smell,GO:0005549//odorant binding,K01830//Arachidonic acid metabolism;Metabolic pathways
29993,10,0,9,0,0,0,0,2,58,0,13,0,PACSIN1;protein kinase C and casein kinase substrate in neurons 1,GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0030659//cytoplasmic vesicle membrane;GO:0043679//axon terminus;GO:0005737//cytoplasm,GO:1900006//positive regulation of dendrite development;GO:0072657//protein localization to membrane;GO:0048812//neuron projection morphogenesis;GO:0007015//actin filament organization;GO:0097320//membrane tubulation;GO:0090002//establishment of protein localization to plasma membrane;GO:0048488//synaptic vesicle endocytosis,GO:0005515//protein binding;GO:0005543//phospholipid binding,K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;K12804//NOD-like receptor signaling pathway;K10408//Huntington's disease
29994,39,90,0,36,89,19,19,0,1,0,46,0,"BAZ2B;bromodomain adjacent to zinc finger domain, 2B",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
29995,0,0,0,0,0,0,0,0,45,0,0,0,LMCD1;LIM and cysteine-rich domains 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031012//extracellular matrix;GO:0005615//extracellular space,"GO:0010611//regulation of cardiac muscle hypertrophy;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003714//transcription corepressor activity,K04511//Wnt signaling pathway
29997,0,1,0,6,2,0,0,114,27,0,0,0,GLTSCR2;glioma tumor suppressor candidate region gene 2,GO:0005622//intracellular;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,-,GO:0044822//poly(A) RNA binding,K14840//Herpes simplex infection
29998,2,0,0,10,0,22,0,0,31,171,0,0,GLTSCR1;glioma tumor suppressor candidate region gene 1,-,-,GO:0005515//protein binding,-
29999,0,19,0,0,0,0,10,0,41,0,14,0,"FSCN3;fascin actin-bundling protein 3, testicular",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton,-,"GO:0030674//protein binding, bridging;GO:0051015//actin filament binding",-
3,1,0,0,0,0,0,0,0,0,0,0,0,A2MP1;alpha-2-macroglobulin pseudogene 1,-,-,-,K03910//Complement and coagulation cascades
30,0,23,0,9,44,4,0,0,23,0,15,0,ACAA1;acetyl-CoA acyltransferase 1,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0044281//small molecule metabolic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0008206//bile acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0044255//cellular lipid metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase,GO:0005515//protein binding;GO:0016401//palmitoyl-CoA oxidase activity;GO:0003988//acetyl-CoA C-acyltransferase activity,"K07513//Metabolic pathways;Valine, leucine and isoleucine degradation;Biosynthesis of unsaturated fatty acids;Fatty acid metabolism;PPAR signaling pathway;alpha-Linolenic acid metabolism;Peroxisome;Biosynthesis of secondary metabolites"
3000,54,10,0,11,13,21,0,0,7,2,24,0,"GUCY2D;guanylate cyclase 2D, membrane (retina-specific)",GO:0005640//nuclear outer membrane;GO:0005887//integral component of plasma membrane;GO:0097381//photoreceptor disc membrane,"GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0007603//phototransduction, visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007601//visual perception;GO:0006182//cGMP biosynthetic process",GO:0004872//receptor activity;GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004383//guanylate cyclase activity,K12321//Phototransduction;Purine metabolism;Olfactory transduction
30000,0,13,0,13,14,36,31,0,45,0,1,10,TNPO2;transportin 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006886//intracellular protein transport,GO:0008536//Ran GTPase binding;GO:0008139//nuclear localization sequence binding;GO:0005515//protein binding,K14293//RNA transport
30001,15,0,0,0,0,34,1,1,86,0,0,0,ERO1L;ERO1-like (S. cerevisiae),GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0050873//brown fat cell differentiation;GO:0055114//oxidation-reduction process;GO:0051209//release of sequestered calcium ion into cytosol;GO:0009266//response to temperature stimulus;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0006464//cellular protein modification process;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0022417//protein maturation by protein folding;GO:0030198//extracellular matrix organization;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,"GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0016491//oxidoreductase activity",K10950//Vibrio cholerae infection;Protein processing in endoplasmic reticulum
30008,0,0,0,0,0,0,44,53,0,0,0,0,EFEMP2;EGF containing fibulin-like extracellular matrix protein 2,GO:0031982//vesicle;GO:0016020//membrane;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0030198//extracellular matrix organization,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0004888//transmembrane signaling receptor activity,K08023//TGF-beta signaling pathway
30009,0,0,0,0,2,11,6,46,45,0,2,0,TBX21;T-box 21,GO:0043025//neuronal cell body;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0030217//T cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0009615//response to virus;GO:0072676//lymphocyte migration;GO:0007275//multicellular organismal development;GO:0071310//cellular response to organic substance;GO:0048304//positive regulation of isotype switching to IgG isotypes",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3001,0,0,0,0,0,0,0,0,15,0,0,0,"GZMA;granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)",GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005576//extracellular region,GO:0051354//negative regulation of oxidoreductase activity;GO:0043392//negative regulation of DNA binding;GO:0032078//negative regulation of endodeoxyribonuclease activity;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0006955//immune response;GO:0019835//cytolysis,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004252//serine-type endopeptidase activity,K01352//Neuroactive ligand-receptor interaction
30010,1,0,0,0,0,0,0,0,0,0,0,0,NXPH1;neurexophilin 1,GO:0005576//extracellular region,-,GO:0005102//receptor binding,-
30011,0,1,0,0,19,43,0,0,49,24,0,0,SH3KBP1;SH3-domain kinase binding protein 1,GO:0043005//neuron projection;GO:0030659//cytoplasmic vesicle membrane;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0005829//cytosol;GO:0005925//focal adhesion,GO:0006915//apoptotic process;GO:0006897//endocytosis;GO:0008360//regulation of cell shape;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007010//cytoskeleton organization;GO:0016477//cell migration;GO:0007267//cell-cell signaling;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0017124//SH3 domain binding,K12470//Endocytosis
30012,0,0,0,0,0,0,3,0,37,0,2,0,TLX3;T-cell leukemia homeobox 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007417//central nervous system development;GO:0001764//neuron migration;GO:0048665//neuron fate specification;GO:0045665//negative regulation of neuron differentiation;GO:0007585//respiratory gaseous exchange;GO:0002087//regulation of respiratory gaseous exchange by neurological system process",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,K15607//Transcriptional misregulation in cancer
3002,0,0,33,0,0,0,0,0,5,0,11,0,"GZMB;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)",GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0001772//immunological synapse;GO:0005634//nucleus,GO:0007219//Notch signaling pathway;GO:0006508//proteolysis;GO:0097193//intrinsic apoptotic signaling pathway;GO:0019835//cytolysis;GO:0006915//apoptotic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K01353//Type I diabetes mellitus;Transcriptional misregulation in cancer;Allograft rejection;Autoimmune thyroid disease;Natural killer cell mediated cytotoxicity;Graft-versus-host disease
3003,0,0,0,0,14,0,0,0,0,0,0,0,GZMK;granzyme K (granzyme 3; tryptase II),GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
3004,0,0,0,0,0,13,0,0,0,0,0,0,GZMM;granzyme M (lymphocyte met-ase 1),GO:0016020//membrane;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0019835//cytolysis;GO:0045087//innate immune response;GO:0006915//apoptotic process,GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,-
3005,0,277,38,462,1777,0,65,0,10,0,8,0,"H1F0;H1 histone family, member 0",GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0015629//actin cytoskeleton;GO:0005719//nuclear euchromatin;GO:0000786//nucleosome,GO:0006334//nucleosome assembly;GO:0006915//apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006309//apoptotic DNA fragmentation,GO:0044822//poly(A) RNA binding;GO:0031490//chromatin DNA binding;GO:0005515//protein binding,-
3006,0,12,2,9,7,0,0,0,0,0,0,0,"HIST1H1C;histone cluster 1, H1c",GO:0005634//nucleus;GO:0005719//nuclear euchromatin;GO:0000786//nucleosome,GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning,GO:0031490//chromatin DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
30061,0,49,0,23,35,0,0,0,103,0,0,0,"SLC40A1;solute carrier family 40 (iron-regulated transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0005771//multivesicular body;GO:0005622//intracellular;GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane,GO:0060586//multicellular organismal iron ion homeostasis;GO:0006879//cellular iron ion homeostasis;GO:0003158//endothelium development;GO:0060345//spleen trabecula formation;GO:0009653//anatomical structure morphogenesis;GO:0034755//iron ion transmembrane transport;GO:0002260//lymphocyte homeostasis;GO:0055085//transmembrane transport;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding;GO:0005381//iron ion transmembrane transporter activity,K14685//Mineral absorption
30062,1,0,0,2,0,0,64,101,13,0,0,665,RAX;retina and anterior neural fold homeobox,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060173//limb development;GO:0006351//transcription, DNA-templated;GO:0021854//hypothalamus development;GO:0007601//visual perception;GO:0007389//pattern specification process;GO:0043010//camera-type eye development",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
3008,0,0,0,0,8,0,0,0,35,0,0,0,"HIST1H1E;histone cluster 1, H1e",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome;GO:0005720//nuclear heterochromatin,GO:0006334//nucleosome assembly;GO:0016584//nucleosome positioning,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0031490//chromatin DNA binding,-
3009,0,0,0,0,0,0,20,0,0,0,0,0,"HIST1H1B;histone cluster 1, H1b",GO:0070062//extracellular vesicular exosome;GO:0005720//nuclear heterochromatin;GO:0000786//nucleosome;GO:0000790//nuclear chromatin,GO:0071169//establishment of protein localization to chromatin;GO:0006334//nucleosome assembly;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0030307//positive regulation of cell growth;GO:0050821//protein stabilization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization,GO:0042826//histone deacetylase binding;GO:0044822//poly(A) RNA binding;GO:0031490//chromatin DNA binding,-
301,0,150,4,172,764,9,0,1,29,0,15,329,ANXA1;annexin A1,GO:0042383//sarcolemma;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0031982//vesicle;GO:0005929//cilium;GO:0031966//mitochondrial membrane;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0018149//peptide cross-linking;GO:0042493//response to drug;GO:0046632//alpha-beta T cell differentiation;GO:0031340//positive regulation of vesicle fusion;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:2000483//negative regulation of interleukin-8 secretion;GO:0002674//negative regulation of acute inflammatory response;GO:0001780//neutrophil homeostasis;GO:0070301//cellular response to hydrogen peroxide;GO:0070365//hepatocyte differentiation;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0097350//neutrophil clearance;GO:0032355//response to estradiol;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007165//signal transduction;GO:0050482//arachidonic acid secretion;GO:0031018//endocrine pancreas development;GO:0042127//regulation of cell proliferation;GO:0070555//response to interleukin-1;GO:0006954//inflammatory response;GO:0060206//estrous cycle phase;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0030073//insulin secretion;GO:0043434//response to peptide hormone;GO:0006928//cellular component movement;GO:0042063//gliogenesis;GO:0043086//negative regulation of catalytic activity;GO:0010165//response to X-ray;GO:0007166//cell surface receptor signaling pathway;GO:0030216//keratinocyte differentiation,"GO:0005198//structural molecule activity;GO:0030674//protein binding, bridging;GO:0019834//phospholipase A2 inhibitor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005102//receptor binding",-
3010,0,0,0,0,0,0,0,83,0,0,0,0,"HIST1H1T;histone cluster 1, H1t",GO:0000786//nucleosome;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus,GO:0007339//binding of sperm to zona pellucida;GO:0006334//nucleosome assembly;GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0030317//sperm motility;GO:0007275//multicellular organismal development,GO:0003677//DNA binding,-
3012,0,0,0,0,1,0,0,0,0,0,0,0,"HIST1H2AE;histone cluster 1, H2ae",-,-,-,K11251//Systemic lupus erythematosus;Alcoholism
3013,41,0,0,0,0,0,0,0,0,0,0,0,"HIST1H2AD;histone cluster 1, H2ad",GO:0005634//nucleus;GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome,-,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11251//Systemic lupus erythematosus;Alcoholism
3014,0,13,0,0,0,0,0,0,15,0,0,0,"H2AFX;H2A histone family, member X","GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0035861//site of double-strand break;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0001673//male germ cell nucleus;GO:0000794//condensed nuclear chromosome;GO:0001741//XY body;GO:0005634//nucleus;GO:0000790//nuclear chromatin",GO:0045739//positive regulation of DNA repair;GO:0007126//meiotic nuclear division;GO:0007283//spermatogenesis;GO:0000724//double-strand break repair via homologous recombination;GO:0006334//nucleosome assembly;GO:0006974//cellular response to DNA damage stimulus;GO:0000077//DNA damage checkpoint;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0006302//double-strand break repair,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0003684//damaged DNA binding,K11251//Alcoholism;Systemic lupus erythematosus
3015,0,1,0,22,34,9,3,0,0,0,10,0,"H2AFZ;H2A histone family, member Z",GO:0001740//Barr body;GO:0005634//nucleus;GO:0005720//nuclear heterochromatin;GO:0005719//nuclear euchromatin;GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071392//cellular response to estradiol stimulus,GO:0046982//protein heterodimerization activity;GO:0031490//chromatin DNA binding;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K11251//Alcoholism;Systemic lupus erythematosus
3017,0,0,0,16,50,0,0,0,5,0,0,0,"HIST1H2BD;histone cluster 1, H2bd",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,GO:0006325//chromatin organization,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Systemic lupus erythematosus;Alcoholism
3018,0,0,0,0,10,0,0,0,17,0,0,0,"HIST1H2BB;histone cluster 1, H2bb",GO:0000786//nucleosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0006334//nucleosome assembly,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,K11252//Alcoholism;Systemic lupus erythematosus
302,0,0,0,0,20,1,0,92,38,0,0,0,ANXA2;annexin A2,GO:0005634//nucleus;GO:0043220//Schmidt-Lanterman incisure;GO:0030496//midbody;GO:0005615//extracellular space;GO:0005938//cell cortex;GO:0005765//lysosomal membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0016020//membrane;GO:0009986//cell surface;GO:0001726//ruffle;GO:0019897//extrinsic component of plasma membrane;GO:0031902//late endosome membrane;GO:0031012//extracellular matrix;GO:0048471//perinuclear region of cytoplasm;GO:0042383//sarcolemma;GO:0005604//basement membrane;GO:0031982//vesicle;GO:0044354//macropinosome;GO:0043234//protein complex;GO:0035749//myelin sheath adaxonal region;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005811//lipid particle;GO:0045121//membrane raft;GO:0042470//melanosome,GO:0072661//protein targeting to plasma membrane;GO:0007589//body fluid secretion;GO:0031340//positive regulation of vesicle fusion;GO:0001525//angiogenesis;GO:0001765//membrane raft assembly;GO:0051290//protein heterotetramerization;GO:0030199//collagen fibril organization;GO:0051099//positive regulation of binding;GO:0006900//membrane budding;GO:0043086//negative regulation of catalytic activity;GO:0071229//cellular response to acid chemical;GO:0042730//fibrinolysis;GO:0036035//osteoclast development;GO:0048146//positive regulation of fibroblast proliferation;GO:0001934//positive regulation of protein phosphorylation,"GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0008092//cytoskeletal protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019834//phospholipase A2 inhibitor activity;GO:0044548//S100 protein binding;GO:0017137//Rab GTPase binding",-
3020,0,0,0,0,0,0,0,0,16,0,0,0,"H3F3A;H3 histone, family 3A",-,-,-,K11253//Systemic lupus erythematosus;Alcoholism;Transcriptional misregulation in cancer
3021,0,229,3,177,711,0,1,0,17,0,4,0,"H3F3B;H3 histone, family 3B (H3.3B)",GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0005576//extracellular region;GO:0000788//nuclear nucleosome;GO:0070062//extracellular vesicular exosome,GO:0007596//blood coagulation;GO:0030307//positive regulation of cell growth;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007420//brain development;GO:0009725//response to hormone,GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K11253//Systemic lupus erythematosus;Alcoholism;Transcriptional misregulation in cancer
3024,0,0,0,0,0,0,0,0,34,0,0,0,"HIST1H1A;histone cluster 1, H1a",GO:0005719//nuclear euchromatin;GO:0000786//nucleosome;GO:0000790//nuclear chromatin,GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis,GO:0005515//protein binding;GO:0031490//chromatin DNA binding,-
3026,18,0,0,0,0,7,23,0,2,44,10,0,HABP2;hyaluronan binding protein 2,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007155//cell adhesion;GO:0006508//proteolysis,GO:0005539//glycosaminoglycan binding;GO:0004252//serine-type endopeptidase activity,-
3028,0,1,0,8,33,0,0,0,13,0,0,0,HSD17B10;hydroxysteroid (17-beta) dehydrogenase 10,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum,GO:0034641//cellular nitrogen compound metabolic process;GO:0008033//tRNA processing;GO:0044281//small molecule metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0006629//lipid metabolic process;GO:0055114//oxidation-reduction process,GO:0047015//3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0008709//cholate 7-alpha-dehydrogenase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030283//testosterone dehydrogenase [NAD(P)] activity,"K08683//Biosynthesis of secondary metabolites;Metabolic pathways;Valine, leucine and isoleucine degradation;Alzheimer's disease"
3029,0,41,30,10,19,0,0,123,12,0,0,0,HAGH;hydroxyacylglutathione hydrolase,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome,GO:0006750//glutathione biosynthetic process,GO:0004416//hydroxyacylglutathione hydrolase activity;GO:0008270//zinc ion binding,K01069//Pyruvate metabolism
303,0,0,0,0,26,0,0,0,0,0,0,0,ANXA2P1;annexin A2 pseudogene 1,-,-,-,-
3030,178,0,2,119,341,33,5,1,20,131,35,0,"HADHA;hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit",GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex;GO:0005743//mitochondrial inner membrane;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion,GO:0032868//response to insulin;GO:0044281//small molecule metabolic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0042493//response to drug;GO:0046474//glycerophospholipid biosynthetic process;GO:0035965//cardiolipin acyl-chain remodeling;GO:0006635//fatty acid beta-oxidation,GO:0051287//NAD binding;GO:0004300//enoyl-CoA hydratase activity;GO:0032403//protein complex binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0005515//protein binding;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0000062//fatty-acyl-CoA binding;GO:0003985//acetyl-CoA C-acetyltransferase activity,"K07515//Fatty acid metabolism;Lysine degradation;Biosynthesis of unsaturated fatty acids;Metabolic pathways;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Fatty acid elongation;Propanoate metabolism;Biosynthesis of secondary metabolites;Tryptophan metabolism;Butanoate metabolism"
3032,0,56,3,38,58,0,0,0,42,0,0,0,"HADHB;hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit",GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005740//mitochondrial envelope;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0016507//mitochondrial fatty acid beta-oxidation multienzyme complex,GO:0046474//glycerophospholipid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0035965//cardiolipin acyl-chain remodeling;GO:0006635//fatty acid beta-oxidation;GO:0044281//small molecule metabolic process,GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0016509//long-chain-3-hydroxyacyl-CoA dehydrogenase activity;GO:0000062//fatty-acyl-CoA binding;GO:0004300//enoyl-CoA hydratase activity;GO:0003988//acetyl-CoA C-acyltransferase activity;GO:0051287//NAD binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0032403//protein complex binding,"K07509//Biosynthesis of secondary metabolites;Fatty acid metabolism;Fatty acid elongation;Valine, leucine and isoleucine degradation;Metabolic pathways"
3033,0,0,0,10,60,33,0,0,1,0,0,0,HADH;hydroxyacyl-CoA dehydrogenase,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane,GO:0042493//response to drug;GO:0006635//fatty acid beta-oxidation;GO:0044255//cellular lipid metabolic process;GO:0046676//negative regulation of insulin secretion;GO:0044281//small molecule metabolic process;GO:0014823//response to activity;GO:0032868//response to insulin,GO:0070403//NAD+ binding;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity,"K00022//Fatty acid metabolism;Lysine degradation;Fatty acid elongation;Metabolic pathways;Valine, leucine and isoleucine degradation;Tryptophan metabolism;Biosynthesis of secondary metabolites;Butanoate metabolism"
3034,0,0,0,0,0,0,0,14,49,0,0,0,HAL;histidine ammonia-lyase,GO:0005829//cytosol,GO:0006548//histidine catabolic process;GO:0009058//biosynthetic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0019557//histidine catabolic process to glutamate and formate;GO:0019556//histidine catabolic process to glutamate and formamide,GO:0004397//histidine ammonia-lyase activity,K01745//Histidine metabolism;Metabolic pathways
3035,0,22,0,44,157,11,0,237,41,0,186,0,HARS;histidyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006412//translation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006427//histidyl-tRNA aminoacylation,GO:0004821//histidine-tRNA ligase activity;GO:0005524//ATP binding,K01892//Aminoacyl-tRNA biosynthesis;Ribosome
3036,0,0,0,0,0,0,40,17,2,0,9,0,HAS1;hyaluronan synthase 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030212//hyaluronan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0085029//extracellular matrix assembly;GO:0005975//carbohydrate metabolic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0010764//negative regulation of fibroblast migration;GO:0007155//cell adhesion;GO:0030213//hyaluronan biosynthetic process,GO:0050501//hyaluronan synthase activity,-
3037,10,0,0,0,0,8,28,0,24,0,21,0,HAS2;hyaluronan synthase 2,GO:0005887//integral component of plasma membrane,GO:0071347//cellular response to interleukin-1;GO:0060349//bone morphogenesis;GO:1900625//positive regulation of monocyte aggregation;GO:0071356//cellular response to tumor necrosis factor;GO:0045226//extracellular polysaccharide biosynthetic process;GO:0030335//positive regulation of cell migration;GO:0036302//atrioventricular canal development;GO:0090500//endocardial cushion to mesenchymal transition;GO:0030213//hyaluronan biosynthetic process;GO:0070295//renal water absorption;GO:0035810//positive regulation of urine volume;GO:0001570//vasculogenesis;GO:0001822//kidney development;GO:0071498//cellular response to fluid shear stress;GO:0085029//extracellular matrix assembly;GO:0008284//positive regulation of cell proliferation;GO:0036120//cellular response to platelet-derived growth factor stimulus,GO:0050501//hyaluronan synthase activity,-
3038,0,891,739,870,1150,25,102,107,78,1,1292,0,HAS3;hyaluronan synthase 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0036117//hyaluranon cable;GO:0016021//integral component of membrane,"GO:1900106//positive regulation of hyaluranon cable assembly;GO:0030213//hyaluronan biosynthetic process;GO:0030212//hyaluronan metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0085029//extracellular matrix assembly;GO:0005975//carbohydrate metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045226//extracellular polysaccharide biosynthetic process",GO:0050501//hyaluronan synthase activity,-
304,0,0,0,0,14,0,12,0,15,0,0,0,ANXA2P2;annexin A2 pseudogene 2,GO:0005604//basement membrane;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome,GO:0043086//negative regulation of catalytic activity,GO:0008092//cytoskeletal protein binding;GO:0004859//phospholipase inhibitor activity;GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation
3043,0,0,0,0,0,0,0,0,31,0,0,0,"HBB;hemoglobin, beta",GO:0031838//haptoglobin-hemoglobin complex;GO:0071682//endocytic vesicle lumen;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005833//hemoglobin complex,GO:0008217//regulation of blood pressure;GO:0050880//regulation of blood vessel size;GO:0055114//oxidation-reduction process;GO:0007596//blood coagulation;GO:0010942//positive regulation of cell death;GO:0015701//bicarbonate transport;GO:0015671//oxygen transport;GO:0051291//protein heterooligomerization;GO:0070527//platelet aggregation;GO:0042542//response to hydrogen peroxide;GO:0030185//nitric oxide transport;GO:0042744//hydrogen peroxide catabolic process;GO:0044281//small molecule metabolic process;GO:0070293//renal absorption;GO:0045429//positive regulation of nitric oxide biosynthetic process,GO:0004601//peroxidase activity;GO:0019825//oxygen binding;GO:0005515//protein binding;GO:0005344//oxygen transporter activity;GO:0020037//heme binding;GO:0030492//hemoglobin binding;GO:0005506//iron ion binding;GO:0031720//haptoglobin binding,K13823//African trypanosomiasis;Malaria
3044,0,0,0,0,0,0,0,0,22,0,0,0,"HBBP1;hemoglobin, beta pseudogene 1",-,-,-,-
3045,113,0,0,0,0,0,0,0,0,0,0,0,"HBD;hemoglobin, delta",GO:0005829//cytosol;GO:0005833//hemoglobin complex;GO:0072562//blood microparticle,GO:0007596//blood coagulation;GO:0015671//oxygen transport,GO:0005344//oxygen transporter activity;GO:0005506//iron ion binding;GO:0019825//oxygen binding;GO:0020037//heme binding,K13823//African trypanosomiasis;Malaria
3048,0,0,0,0,0,0,25,72,37,0,0,0,"HBG2;hemoglobin, gamma G",GO:0072562//blood microparticle;GO:0005829//cytosol;GO:0005833//hemoglobin complex,GO:0007596//blood coagulation;GO:0015671//oxygen transport,GO:0005506//iron ion binding;GO:0005344//oxygen transporter activity;GO:0019825//oxygen binding;GO:0020037//heme binding,-
3049,0,0,0,0,0,0,0,0,3,0,4,0,"HBQ1;hemoglobin, theta 1",GO:0005833//hemoglobin complex,GO:0015671//oxygen transport,GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0005344//oxygen transporter activity;GO:0005506//iron ion binding,-
305,0,0,0,0,0,0,0,0,7,0,0,0,ANXA2P3;annexin A2 pseudogene 3,-,-,-,-
3052,20,0,0,0,0,0,0,0,17,0,0,301,HCCS;holocytochrome c synthase,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process;GO:0009887//organ morphogenesis,GO:0046872//metal ion binding;GO:0004408//holocytochrome-c synthase activity,K01764//Porphyrin and chlorophyll metabolism
3053,0,0,0,0,0,9,34,0,11,0,0,0,"SERPIND1;serpin peptidase inhibitor, clade D (heparin cofactor), member 1",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0007596//blood coagulation;GO:0006935//chemotaxis;GO:0030162//regulation of proteolysis,GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding,K03912//Complement and coagulation cascades
3054,15,0,0,13,33,6,70,3,23,53,5,0,HCFC1;host cell factor C1,GO:0005730//nucleolus;GO:0070461//SAGA-type complex;GO:0005739//mitochondrion;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0005634//nucleus;GO:0048188//Set1C/COMPASS complex;GO:0070688//MLL5-L complex;GO:0016020//membrane;GO:0000123//histone acetyltransferase complex;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm,"GO:0043982//histone H4-K8 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045787//positive regulation of cell cycle;GO:0043984//histone H4-K16 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0043254//regulation of protein complex assembly;GO:0043981//histone H4-K5 acetylation;GO:0019046//release from viral latency;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0050821//protein stabilization;GO:0010628//positive regulation of gene expression",GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific),K14966//Herpes simplex infection
3055,1,0,0,0,0,0,0,0,8,0,0,0,"HCK;HCK proto-oncogene, Src family tyrosine kinase",GO:0005764//lysosome;GO:0005884//actin filament;GO:0042995//cell projection;GO:0005901//caveola;GO:0005634//nucleus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030133//transport vesicle;GO:0005794//Golgi apparatus,GO:0071801//regulation of podosome assembly;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0050727//regulation of inflammatory response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0007498//mesoderm development;GO:0008360//regulation of cell shape;GO:0002522//leukocyte migration involved in immune response;GO:0045087//innate immune response;GO:0002758//innate immune response-activating signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0043299//leukocyte degranulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006468//protein phosphorylation;GO:0050690//regulation of defense response to virus by virus;GO:0019221//cytokine-mediated signaling pathway;GO:0050764//regulation of phagocytosis;GO:0007155//cell adhesion;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0006954//inflammatory response;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0030838//positive regulation of actin filament polymerization;GO:0045728//respiratory burst after phagocytosis;GO:0016032//viral process;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0046777//protein autophosphorylation,GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,K08893//Fc gamma R-mediated phagocytosis;Chemokine signaling pathway
3059,0,0,0,0,0,26,0,0,42,0,0,0,HCLS1;hematopoietic cell-specific Lyn substrate 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005739//mitochondrion,"GO:0045651//positive regulation of macrophage differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0030833//regulation of actin filament polymerization;GO:0051897//positive regulation of protein kinase B signaling;GO:0030218//erythrocyte differentiation;GO:0030854//positive regulation of granulocyte differentiation;GO:0035556//intracellular signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030041//actin filament polymerization;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0009725//response to hormone;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0071345//cellular response to cytokine stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:2000107//negative regulation of leukocyte apoptotic process",GO:0032403//protein complex binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0017124//SH3 domain binding;GO:0001085//RNA polymerase II transcription factor binding,K06106//Tight junction;Bacterial invasion of epithelial cells;Pathogenic Escherichia coli infection;Shigellosis
306,38,52,1,42,146,25,2,0,24,0,0,0,ANXA3;annexin A3,GO:0005737//cytoplasm;GO:0042581//specific granule;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0043312//neutrophil degranulation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006909//phagocytosis;GO:0043086//negative regulation of catalytic activity;GO:0045766//positive regulation of angiogenesis;GO:0010595//positive regulation of endothelial cell migration;GO:0042742//defense response to bacterium,GO:0019834//phospholipase A2 inhibitor activity;GO:0005544//calcium-dependent phospholipid binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding,-
3060,0,0,0,0,4,0,0,0,0,0,8,22,HCRT;hypocretin (orexin) neuropeptide precursor,GO:0048471//perinuclear region of cytoplasm;GO:0005791//rough endoplasmic reticulum;GO:0030054//cell junction;GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0008021//synaptic vesicle,GO:0008156//negative regulation of DNA replication;GO:0051970//negative regulation of transmission of nerve impulse;GO:0046928//regulation of neurotransmitter secretion;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0051971//positive regulation of transmission of nerve impulse;GO:0007268//synaptic transmission;GO:0007218//neuropeptide signaling pathway;GO:0043267//negative regulation of potassium ion transport;GO:0051928//positive regulation of calcium ion transport;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0042755//eating behavior,GO:0031772//type 2 hypocretin receptor binding;GO:0031771//type 1 hypocretin receptor binding,-
3061,0,0,0,0,0,0,27,46,24,0,0,0,HCRTR1;hypocretin (orexin) receptor 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0007268//synaptic transmission,GO:0016499//orexin receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0017046//peptide hormone binding,K04238//Neuroactive ligand-receptor interaction
3062,0,0,0,0,0,0,0,1,33,0,0,0,HCRTR2;hypocretin (orexin) receptor 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007268//synaptic transmission;GO:0022410//circadian sleep/wake cycle process;GO:0007631//feeding behavior;GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity;GO:0016499//orexin receptor activity,K04239//Neuroactive ligand-receptor interaction
3064,0,68,1,20,122,18,33,40,105,0,1,0,HTT;huntingtin,GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0030659//cytoplasmic vesicle membrane;GO:0016234//inclusion body;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0030424//axon;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005776//autophagic vacuole,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0000052//citrulline metabolic process;GO:0008340//determination of adult lifespan;GO:0007030//Golgi organization;GO:0021756//striatum development;GO:0007029//endoplasmic reticulum organization;GO:0000132//establishment of mitotic spindle orientation;GO:0007569//cell aging;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0000050//urea cycle;GO:0048341//paraxial mesoderm formation;GO:0008088//axon cargo transport;GO:0055072//iron ion homeostasis;GO:0046902//regulation of mitochondrial membrane permeability;GO:0051402//neuron apoptotic process;GO:0007212//dopamine receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0048513//organ development;GO:0034047//regulation of protein phosphatase type 2A activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0006606//protein import into nucleus;GO:0007625//grooming behavior;GO:0042445//hormone metabolic process;GO:0008542//visual learning;GO:0019805//quinolinate biosynthetic process;GO:0030073//insulin secretion;GO:0021988//olfactory lobe development;GO:0009952//anterior/posterior pattern specification;GO:0051592//response to calcium ion;GO:0007283//spermatogenesis;GO:0021990//neural plate formation;GO:0051938//L-glutamate import;GO:0047496//vesicle transport along microtubule;GO:0016197//endosomal transport;GO:0035176//social behavior;GO:0051881//regulation of mitochondrial membrane potential;GO:0048666//neuron development;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0007626//locomotory behavior;GO:0019244//lactate biosynthetic process from pyruvate;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity",GO:0042802//identical protein binding;GO:0002039//p53 binding;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0045505//dynein intermediate chain binding;GO:0008134//transcription factor binding;GO:0050809//diazepam binding;GO:0034452//dynactin binding,K04533//Huntington's disease
3065,34,70,1,62,157,0,0,54,7,0,0,0,HDAC1;histone deacetylase 1,GO:0016580//Sin3 complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0000118//histone deacetylase complex;GO:0000785//chromatin;GO:0016581//NuRD complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0042733//embryonic digit morphogenesis;GO:0032922//circadian regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061198//fungiform papilla formation;GO:0043922//negative regulation by host of viral transcription;GO:0070932//histone H3 deacetylation;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0043044//ATP-dependent chromatin remodeling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0009913//epidermal cell differentiation;GO:0000278//mitotic cell cycle;GO:0006476//protein deacetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010870//positive regulation of receptor biosynthetic process;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0060789//hair follicle placode formation;GO:0008284//positive regulation of cell proliferation;GO:0061029//eyelid development in camera-type eye;GO:0010832//negative regulation of myotube differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0070933//histone H4 deacetylation;GO:0006338//chromatin remodeling;GO:0016575//histone deacetylation;GO:0007596//blood coagulation;GO:0045786//negative regulation of cell cycle;GO:0042475//odontogenesis of dentin-containing tooth;GO:0016032//viral process;GO:0016568//chromatin modification",GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0044212//transcription regulatory region DNA binding;GO:0019213//deacetylase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0031492//nucleosomal DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0033613//activating transcription factor binding;GO:0042826//histone deacetylase binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001047//core promoter binding;GO:0033558//protein deacetylase activity;GO:0019899//enzyme binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0070491//repressing transcription factor binding;GO:0004407//histone deacetylase activity,K06067//Pathways in cancer;Huntington's disease;Transcriptional misregulation in cancer;Alcoholism;Amphetamine addiction;Chronic myeloid leukemia;Notch signaling pathway;Cell cycle;Epstein-Barr virus infection
3066,0,3,0,43,144,2,49,57,41,89,0,0,HDAC2;histone deacetylase 2,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0016581//NuRD complex;GO:0000792//heterochromatin;GO:0005667//transcription factor complex;GO:0035098//ESC/E(Z) complex;GO:0005737//cytoplasm;GO:0005657//replication fork;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016580//Sin3 complex,"GO:0042475//odontogenesis of dentin-containing tooth;GO:0045786//negative regulation of cell cycle;GO:0060297//regulation of sarcomere organization;GO:0016358//dendrite development;GO:0070933//histone H4 deacetylation;GO:0006344//maintenance of chromatin silencing;GO:0016575//histone deacetylation;GO:0006338//chromatin remodeling;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007596//blood coagulation;GO:0045862//positive regulation of proteolysis;GO:0060789//hair follicle placode formation;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0061029//eyelid development in camera-type eye;GO:0021766//hippocampus development;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0010870//positive regulation of receptor biosynthetic process;GO:0055013//cardiac muscle cell development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090311//regulation of protein deacetylation;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0009913//epidermal cell differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061198//fungiform papilla formation;GO:0070932//histone H3 deacetylation;GO:0010977//negative regulation of neuron projection development;GO:0043044//ATP-dependent chromatin remodeling;GO:0042733//embryonic digit morphogenesis;GO:0032922//circadian regulation of gene expression;GO:0051896//regulation of protein kinase B signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0019213//deacetylase activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0004407//histone deacetylase activity;GO:0003682//chromatin binding;GO:0033558//protein deacetylase activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0035851//Krueppel-associated box domain binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific),K06067//Alcoholism;Transcriptional misregulation in cancer;Huntington's disease;Pathways in cancer;Epstein-Barr virus infection;Notch signaling pathway;Cell cycle;Chronic myeloid leukemia;Amphetamine addiction
3067,94,0,0,0,0,0,0,0,18,0,24,0,HDC;histidine decarboxylase,GO:0005829//cytosol,GO:0006548//histidine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0042423//catecholamine biosynthetic process;GO:0001694//histamine biosynthetic process;GO:0044281//small molecule metabolic process,GO:0004398//histidine decarboxylase activity;GO:0030170//pyridoxal phosphate binding,K01590//Biosynthesis of secondary metabolites;Histidine metabolism;Metabolic pathways
3068,0,33,0,16,146,24,1,1,0,202,0,0,HDGF;hepatoma-derived growth factor,GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044267//cellular protein metabolic process;GO:0006351//transcription, DNA-templated;GO:0034504//protein localization to nucleus;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001222//transcription corepressor binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0008201//heparin binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003677//DNA binding;GO:0008083//growth factor activity,"K00020//Valine, leucine and isoleucine degradation;Metabolic pathways;Pentose phosphate pathway;Glutathione metabolism"
3069,37,365,7,405,1262,47,0,106,68,48,150,1,HDLBP;high density lipoprotein binding protein,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0034364//high-density lipoprotein particle;GO:0005737//cytoplasm,GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008289//lipid binding,K12886//Spliceosome;Herpes simplex infection
307,64,2,31,38,72,8,0,2,13,0,0,0,ANXA4;annexin A4,GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0012506//vesicle membrane,GO:0043066//negative regulation of apoptotic process;GO:2000483//negative regulation of interleukin-8 secretion;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0030855//epithelial cell differentiation;GO:0043086//negative regulation of catalytic activity,GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042802//identical protein binding;GO:0051059//NF-kappaB binding;GO:0005544//calcium-dependent phospholipid binding;GO:0004859//phospholipase inhibitor activity,-
3070,14,0,0,0,3,8,43,0,41,0,0,0,"HELLS;helicase, lymphoid-specific","GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005721//pericentric heterochromatin","GO:0043066//negative regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006346//methylation-dependent chromatin silencing;GO:0010216//maintenance of DNA methylation;GO:0007067//mitotic nuclear division;GO:0001655//urogenital system development;GO:0031508//pericentric heterochromatin assembly;GO:0006306//DNA methylation;GO:0046651//lymphocyte proliferation",GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0005524//ATP binding,-
3071,0,0,0,0,0,23,14,0,5,0,7,0,NCKAP1L;NCK-associated protein 1-like,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0031209//SCAR complex,"GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0043066//negative regulation of apoptotic process;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0030593//neutrophil chemotaxis;GO:0032855//positive regulation of Rac GTPase activity;GO:0045648//positive regulation of erythrocyte differentiation;GO:0042327//positive regulation of phosphorylation;GO:0043029//T cell homeostasis;GO:0035509//negative regulation of myosin-light-chain-phosphatase activity;GO:0070358//actin polymerization-dependent cell motility;GO:0002262//myeloid cell homeostasis;GO:0048821//erythrocyte development;GO:0050853//B cell receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0042493//response to drug;GO:0006461//protein complex assembly;GO:0043378//positive regulation of CD8-positive, alpha-beta T cell differentiation;GO:0001782//B cell homeostasis;GO:0030011//maintenance of cell polarity;GO:0006935//chemotaxis;GO:0030866//cortical actin cytoskeleton organization;GO:0032700//negative regulation of interleukin-17 production;GO:0045860//positive regulation of protein kinase activity;GO:0045579//positive regulation of B cell differentiation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0030838//positive regulation of actin filament polymerization;GO:0032715//negative regulation of interleukin-6 production;GO:0042102//positive regulation of T cell proliferation",GO:0030675//Rac GTPase activator activity;GO:0005515//protein binding;GO:0032403//protein complex binding;GO:0030295//protein kinase activator activity,K05750//Regulation of actin cytoskeleton
3073,72,30,0,45,3,0,11,2,24,1,6,1,HEXA;hexosaminidase A (alpha polypeptide),GO:0043202//lysosomal lumen;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0030204//chondroitin sulfate metabolic process;GO:0042340//keratan sulfate catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030214//hyaluronan catabolic process;GO:0030212//hyaluronan metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0008219//cell death,GO:0004563//beta-N-acetylhexosaminidase activity;GO:0046982//protein heterodimerization activity,K12373//Lysosome;Other glycan degradation;Glycosphingolipid biosynthesis - globo series;Glycosaminoglycan degradation;ABC transporters;Glycosphingolipid biosynthesis - ganglio series;Metabolic pathways;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;RNA degradation
3074,111,54,85,29,52,0,0,117,51,0,105,354,HEXB;hexosaminidase B (beta polypeptide),GO:0043202//lysosomal lumen;GO:0001669//acrosomal vesicle;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0007040//lysosome organization;GO:0042340//keratan sulfate catabolic process;GO:0050885//neuromuscular process controlling balance;GO:0008360//regulation of cell shape;GO:0043615//astrocyte cell migration;GO:0048477//oogenesis;GO:0030204//chondroitin sulfate metabolic process;GO:0008049//male courtship behavior;GO:0008219//cell death;GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0006874//cellular calcium ion homeostasis;GO:0044281//small molecule metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0042552//myelination;GO:0006665//sphingolipid metabolic process;GO:0001501//skeletal system development;GO:0006689//ganglioside catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0019915//lipid storage;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030212//hyaluronan metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0030214//hyaluronan catabolic process;GO:0007341//penetration of zona pellucida;GO:0030203//glycosaminoglycan metabolic process,GO:0046982//protein heterodimerization activity;GO:0004563//beta-N-acetylhexosaminidase activity;GO:0042803//protein homodimerization activity,K12373//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;RNA degradation;Lysosome;Other glycan degradation;Glycosphingolipid biosynthesis - globo series;Glycosaminoglycan degradation;Glycosphingolipid biosynthesis - ganglio series;ABC transporters;Metabolic pathways
3075,165,0,0,0,0,10,0,0,80,0,13,2,CFH;complement factor H,GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,"GO:0030449//regulation of complement activation;GO:0006957//complement activation, alternative pathway;GO:0006956//complement activation;GO:0045087//innate immune response",GO:0008201//heparin binding;GO:0005515//protein binding;GO:0043395//heparan sulfate proteoglycan binding,K04004//Staphylococcus aureus infection;Complement and coagulation cascades
3078,0,0,0,0,0,0,0,0,0,0,6,0,CFHR1;complement factor H-related 1,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle,GO:0006956//complement activation,-,K04004//Complement and coagulation cascades;Staphylococcus aureus infection
308,0,105,1,72,442,7,0,10,14,0,6,0,ANXA5;annexin A5,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0072563//endothelial microparticle;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005622//intracellular,GO:0010033//response to organic substance;GO:0043086//negative regulation of catalytic activity;GO:0007596//blood coagulation;GO:0050819//negative regulation of coagulation;GO:0043066//negative regulation of apoptotic process;GO:0007165//signal transduction,GO:0005543//phospholipid binding;GO:0005509//calcium ion binding;GO:0004859//phospholipase inhibitor activity;GO:0005544//calcium-dependent phospholipid binding,-
3080,0,0,0,0,0,0,0,0,0,0,1,0,CFHR2;complement factor H-related 2,GO:0005576//extracellular region,-,-,K04004//Staphylococcus aureus infection;Complement and coagulation cascades
3081,0,39,1,64,93,10,0,4,25,0,0,0,"HGD;homogentisate 1,2-dioxygenase",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006572//tyrosine catabolic process;GO:0055114//oxidation-reduction process;GO:0006559//L-phenylalanine catabolic process,"GO:0004411//homogentisate 1,2-dioxygenase activity;GO:0046872//metal ion binding",K00451//Metabolic pathways;Tyrosine metabolism;Microbial metabolism in diverse environments;Styrene degradation
30811,0,0,0,14,0,7,61,0,16,98,3,0,HUNK;hormonally up-regulated Neu-associated kinase,-,GO:0007275//multicellular organismal development;GO:0007165//signal transduction;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
30812,0,0,0,0,0,0,0,73,30,0,0,0,SOX8;SRY (sex determining region Y)-box 8,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex,"GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060612//adipose tissue development;GO:0048484//enteric nervous system development;GO:0090184//positive regulation of kidney development;GO:0007422//peripheral nervous system development;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0001701//in utero embryonic development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045165//cell fate commitment;GO:0014015//positive regulation of gliogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0060221//retinal rod cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0072034//renal vesicle induction;GO:0060018//astrocyte fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0072197//ureter morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0033690//positive regulation of osteoblast proliferation;GO:0061138//morphogenesis of a branching epithelium;GO:0010817//regulation of hormone levels;GO:0060009//Sertoli cell development;GO:0048469//cell maturation;GO:0035914//skeletal muscle cell differentiation;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:0001755//neural crest cell migration;GO:0060041//retina development in camera-type eye;GO:0072289//metanephric nephron tubule formation;GO:0048709//oligodendrocyte differentiation;GO:0001649//osteoblast differentiation",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008134//transcription factor binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,-
30813,0,0,0,2,0,26,11,1,32,0,0,0,VSX1;visual system homeobox 1,GO:0005634//nucleus,"GO:0050896//response to stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0042551//neuron maturation;GO:0060040//retinal bipolar neuron differentiation;GO:0007601//visual perception;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
30815,0,26,1,0,0,0,0,32,0,1,0,1,"ST6GALNAC6;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0001574//ganglioside biosynthetic process;GO:0006687//glycosphingolipid metabolic process;GO:0009100//glycoprotein metabolic process;GO:0009988//cell-cell recognition;GO:0006677//glycosylceramide metabolic process;GO:0097503//sialylation;GO:0009312//oligosaccharide biosynthetic process;GO:0006486//protein glycosylation,"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity",K03376//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
30817,0,0,0,13,0,37,51,32,42,0,15,0,"EMR2;egf-like module containing, mucin-like, hormone receptor-like 2",GO:0031256//leading edge membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0032587//ruffle membrane,GO:0071621//granulocyte chemotaxis;GO:0016477//cell migration;GO:0006954//inflammatory response;GO:0007218//neuropeptide signaling pathway;GO:0007155//cell adhesion;GO:0007186//G-protein coupled receptor signaling pathway,GO:0035374//chondroitin sulfate binding;GO:0005509//calcium ion binding;GO:0004930//G-protein coupled receptor activity,-
30818,112,0,0,0,0,18,0,52,46,0,2,0,"KCNIP3;Kv channel interacting protein 3, calsenilin",GO:0043679//axon terminus;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0032993//protein-DNA complex;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019233//sensory perception of pain;GO:0048266//behavioral response to pain;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0043523//regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process",GO:0005244//voltage-gated ion channel activity;GO:0008022//protein C-terminus binding;GO:0005267//potassium channel activity;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0044325//ion channel binding;GO:0003714//transcription corepressor activity;GO:0003677//DNA binding;GO:0015459//potassium channel regulator activity;GO:0043565//sequence-specific DNA binding,K13764//Phototransduction
30819,0,0,3,43,0,11,0,64,69,0,81,0,KCNIP2;Kv channel interacting protein 2,GO:0005737//cytoplasm;GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006936//muscle contraction;GO:0086009//membrane repolarization;GO:0006813//potassium ion transport;GO:0071435//potassium ion export;GO:0008016//regulation of heart contraction;GO:0007165//signal transduction;GO:0005513//detection of calcium ion;GO:2001257//regulation of cation channel activity;GO:0045163//clustering of voltage-gated potassium channels,GO:0046923//ER retention sequence binding;GO:0005509//calcium ion binding;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0005250//A-type (transient outward) potassium channel activity;GO:0042802//identical protein binding;GO:0015459//potassium channel regulator activity,K13764//Phototransduction
3082,83,0,0,0,0,11,0,0,33,0,0,0,HGF;hepatocyte growth factor (hepapoietin A; scatter factor),GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen,GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050918//positive chemotaxis;GO:0031100//organ regeneration;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001837//epithelial to mesenchymal transition;GO:0001889//liver development;GO:0060326//cell chemotaxis;GO:0045669//positive regulation of osteoblast differentiation;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:1901299//negative regulation of hydrogen peroxide-mediated programmed cell death;GO:0000187//activation of MAPK activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043066//negative regulation of apoptotic process;GO:0030335//positive regulation of cell migration;GO:2000573//positive regulation of DNA biosynthetic process;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0030168//platelet activation;GO:0007067//mitotic nuclear division;GO:0030212//hyaluronan metabolic process;GO:0007596//blood coagulation;GO:0051450//myoblast proliferation;GO:0002576//platelet degranulation;GO:0006508//proteolysis;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling,GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042056//chemoattractant activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0004252//serine-type endopeptidase activity,K05460//Malaria;Pathways in cancer;Cytokine-cytokine receptor interaction;Melanoma;Focal adhesion;Renal cell carcinoma
30820,0,0,0,0,6,0,0,0,28,0,0,0,KCNIP1;Kv channel interacting protein 1,GO:0034705//potassium channel complex;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0043025//neuronal cell body,GO:0045760//positive regulation of action potential;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0007165//signal transduction;GO:0005513//detection of calcium ion,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0046982//protein heterodimerization activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0015459//potassium channel regulator activity;GO:0047485//protein N-terminus binding,K13764//Phototransduction
30827,22,1,0,0,9,0,22,29,40,0,12,0,CXXC1;CXXC finger protein 1,GO:0048188//Set1C/COMPASS complex;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0035097//histone methyltransferase complex;GO:0005634//nucleus;GO:0016607//nuclear speck,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0044267//cellular protein metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0030968//endoplasmic reticulum unfolded protein response",GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0005515//protein binding;GO:0045322//unmethylated CpG binding;GO:0008270//zinc ion binding,-
3083,1,0,0,0,0,0,41,0,10,0,0,0,HGFAC;HGF activator,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005791//rough endoplasmic reticulum,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,-
30832,0,0,0,0,1,0,0,0,11,0,0,0,ZNF354C;zinc finger protein 354C,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
30833,0,0,0,0,1,0,0,0,0,0,0,0,"NT5C;5', 3'-nucleotidase, cytosolic",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006206//pyrimidine nucleobase metabolic process;GO:0016311//dephosphorylation;GO:0046135//pyrimidine nucleoside catabolic process;GO:0009223//pyrimidine deoxyribonucleotide catabolic process;GO:0044281//small molecule metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006195//purine nucleotide catabolic process,GO:0008253//5'-nucleotidase activity;GO:0019103//pyrimidine nucleotide binding;GO:0046872//metal ion binding,K01081//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Nicotinate and nicotinamide metabolism;Metabolic pathways
30835,0,0,0,0,0,0,2,0,0,0,11,0,CD209;CD209 molecule,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane,GO:0007159//leukocyte cell-cell adhesion;GO:0045087//innate immune response;GO:0042129//regulation of T cell proliferation;GO:0046968//peptide antigen transport;GO:0035556//intracellular signal transduction;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0075733//intracellular transport of virus;GO:0019048//modulation by virus of host morphology or physiology;GO:0009988//cell-cell recognition;GO:0019079//viral genome replication;GO:0006897//endocytosis;GO:0019882//antigen processing and presentation;GO:0019062//virion attachment to host cell,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0042605//peptide antigen binding;GO:0005537//mannose binding;GO:0005515//protein binding;GO:0046790//virion binding,K06563//Measles;Tuberculosis;Phagosome
30836,25,0,0,16,45,0,13,0,27,0,0,0,"DNTTIP2;deoxynucleotidyltransferase, terminal, interacting protein 2",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding,K11205//Glutathione metabolism;Metabolic pathways
30837,0,0,44,0,25,0,0,1,19,118,71,0,SOCS7;suppressor of cytokine signaling 7,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0040008//regulation of growth;GO:0045444//fat cell differentiation;GO:0016567//protein ubiquitination;GO:0009968//negative regulation of signal transduction;GO:0008286//insulin receptor signaling pathway;GO:0035556//intracellular signal transduction,GO:0017124//SH3 domain binding;GO:0005515//protein binding,K04699//Jak-STAT signaling pathway
3084,156,0,0,0,0,5,0,0,70,0,1,0,NRG1;neuregulin 1,GO:0005615//extracellular space;GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0016020//membrane;GO:0031594//neuromuscular junction;GO:0005576//extracellular region;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0007154//cell communication;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042060//wound healing;GO:0000165//MAPK cascade;GO:0007422//peripheral nervous system development;GO:0003161//cardiac conduction system development;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0048663//neuron fate commitment;GO:0043497//regulation of protein heterodimerization activity;GO:0045785//positive regulation of cell adhesion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051048//negative regulation of secretion;GO:0014032//neural crest cell development;GO:0000902//cell morphogenesis;GO:0045213//neurotransmitter receptor metabolic process;GO:0055007//cardiac muscle cell differentiation;GO:0042177//negative regulation of protein catabolic process;GO:0007399//nervous system development;GO:0030879//mammary gland development;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0046579//positive regulation of Ras protein signal transduction;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0007626//locomotory behavior;GO:0009790//embryo development;GO:0051897//positive regulation of protein kinase B signaling;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045087//innate immune response;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0038127//ERBB signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016477//cell migration;GO:0007416//synapse assembly;GO:0060956//endocardial cell differentiation;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0043624//cellular protein complex disassembly;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043496//regulation of protein homodimerization activity;GO:0021781//glial cell fate commitment;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway",GO:0030296//protein tyrosine kinase activator activity;GO:0030971//receptor tyrosine kinase binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity;GO:0043125//ErbB-3 class receptor binding;GO:0003712//transcription cofactor activity;GO:0005102//receptor binding;GO:0008083//growth factor activity;GO:0005176//ErbB-2 class receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K05455//ErbB signaling pathway
30844,0,60,1,11,20,0,0,0,5,0,0,0,EHD4;EH-domain containing 4,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane,GO:0032456//endocytic recycling;GO:0006907//pinocytosis;GO:0051260//protein homooligomerization;GO:0030100//regulation of endocytosis;GO:0006184//GTP catabolic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071363//cellular response to growth factor stimulus,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0003676//nucleic acid binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005524//ATP binding,K12477//Endocytosis
30845,0,0,0,0,11,0,14,59,31,0,0,0,EHD3;EH-domain containing 3,GO:0055038//recycling endosome membrane;GO:0005925//focal adhesion;GO:0030139//endocytic vesicle;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005737//cytoplasm,GO:0072661//protein targeting to plasma membrane;GO:0032456//endocytic recycling;GO:0007596//blood coagulation;GO:0051260//protein homooligomerization;GO:0006184//GTP catabolic process;GO:0086036//regulation of cardiac muscle cell membrane potential,GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0003676//nucleic acid binding;GO:0003924//GTPase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding,K12476//Endocytosis
30846,0,0,0,0,0,0,0,0,63,119,9,0,EHD2;EH-domain containing 2,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0055038//recycling endosome membrane,GO:0032456//endocytic recycling;GO:1901741//positive regulation of myoblast fusion;GO:2001137//positive regulation of endocytic recycling;GO:0007596//blood coagulation;GO:0072659//protein localization to plasma membrane;GO:0030866//cortical actin cytoskeleton organization;GO:0006184//GTP catabolic process;GO:0006897//endocytosis,GO:0005524//ATP binding;GO:0003676//nucleic acid binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019904//protein domain specific binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K12469//Endocytosis
30848,0,0,0,0,0,0,0,0,13,0,0,0,CTAG2;cancer/testis antigen 2,GO:0005813//centrosome,-,-,-
30849,0,0,0,0,20,0,36,0,119,0,0,0,"PIK3R4;phosphoinositide-3-kinase, regulatory subunit 4",GO:0005930//axoneme;GO:0005829//cytosol;GO:0016020//membrane;GO:0005770//late endosome,GO:0002224//toll-like receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006468//protein phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0045087//innate immune response;GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,K08333//Regulation of autophagy
30850,14,7,0,0,0,0,14,0,11,0,4,0,CDR2L;cerebellar degeneration-related protein 2-like,-,-,-,-
30851,0,0,0,0,7,0,0,0,8,0,0,0,TAX1BP3;Tax1 (human T-cell leukemia virus type I) binding protein 3,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032864//activation of Cdc42 GTPase activity;GO:2000009//negative regulation of protein localization to cell surface;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007266//Rho protein signal transduction;GO:0008285//negative regulation of cell proliferation,GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding;GO:0005515//protein binding,-
3087,0,0,0,0,0,0,0,0,18,0,1,0,HHEX;hematopoietically expressed homeobox,GO:0032993//protein-DNA complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0035264//multicellular organism growth;GO:0031016//pancreas development;GO:0007492//endoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090009//primitive streak formation;GO:0001701//in utero embryonic development;GO:0061010//gall bladder development;GO:0001570//vasculogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034504//protein localization to nucleus;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043434//response to peptide hormone;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0061011//hepatic duct development;GO:0030878//thyroid gland development;GO:0030183//B cell differentiation;GO:0006351//transcription, DNA-templated;GO:0071103//DNA conformation change;GO:0070365//hepatocyte differentiation;GO:0008283//cell proliferation;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0002573//myeloid leukocyte differentiation;GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0061017//hepatoblast differentiation;GO:0060431//primary lung bud formation;GO:0009952//anterior/posterior pattern specification;GO:0022027//interkinetic nuclear migration;GO:0016525//negative regulation of angiogenesis;GO:0035050//embryonic heart tube development;GO:0042127//regulation of cell proliferation;GO:0009611//response to wounding;GO:0016055//Wnt signaling pathway;GO:0048853//forebrain morphogenesis","GO:0017025//TBP-class protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003682//chromatin binding;GO:0008301//DNA binding, bending;GO:0008190//eukaryotic initiation factor 4E binding;GO:0070491//repressing transcription factor binding;GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding",K08024//Maturity onset diabetes of the young;Transcriptional misregulation in cancer
309,88,0,0,2,42,0,4,0,49,0,2,0,ANXA6;annexin A6,GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,GO:0006816//calcium ion transport;GO:0051260//protein homooligomerization;GO:0034220//ion transmembrane transport;GO:0006937//regulation of muscle contraction,GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0015276//ligand-gated ion channel activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0015485//cholesterol binding;GO:0008289//lipid binding;GO:0005525//GTP binding,-
3090,0,0,0,0,0,14,0,0,4,1,0,0,HIC1;hypermethylated in cancer 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000785//chromatin;GO:0005730//nucleolus,"GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042826//histone deacetylase binding,-
3091,0,19,0,8,102,0,0,0,0,0,14,0,"HIF1A;hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0031514//motile cilium;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0045821//positive regulation of glycolytic process;GO:0046886//positive regulation of hormone biosynthetic process;GO:0032722//positive regulation of chemokine production;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0021502//neural fold elevation formation;GO:0001525//angiogenesis;GO:0051216//cartilage development;GO:0071542//dopaminergic neuron differentiation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0035162//embryonic hemopoiesis;GO:0007595//lactation;GO:0008542//visual learning;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0001892//embryonic placenta development;GO:0001922//B-1 B cell homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0071456//cellular response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0001837//epithelial to mesenchymal transition;GO:0010468//regulation of gene expression;GO:0001666//response to hypoxia;GO:0046716//muscle cell cellular homeostasis;GO:0019896//axon transport of mitochondrion;GO:0048546//digestive tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0045648//positive regulation of erythrocyte differentiation;GO:0002052//positive regulation of neuroblast proliferation;GO:0042593//glucose homeostasis;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0061298//retina vasculature development in camera-type eye;GO:0071347//cellular response to interleukin-1;GO:0006089//lactate metabolic process;GO:0021987//cerebral cortex development;GO:0014850//response to muscle activity;GO:0001755//neural crest cell migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0003151//outflow tract morphogenesis;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0032909//regulation of transforming growth factor beta2 production;GO:0001947//heart looping;GO:0001938//positive regulation of endothelial cell proliferation;GO:0032963//collagen metabolic process;GO:0070101//positive regulation of chemokine-mediated signaling pathway;GO:0010573//vascular endothelial growth factor production;GO:0060574//intestinal epithelial cell maturation;GO:0030502//negative regulation of bone mineralization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006879//cellular iron ion homeostasis;GO:0051541//elastin metabolic process;GO:0032007//negative regulation of TOR signaling;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0010634//positive regulation of epithelial cell migration;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0045926//negative regulation of growth;GO:0032364//oxygen homeostasis;GO:0010870//positive regulation of receptor biosynthetic process;GO:0042541//hemoglobin biosynthetic process;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0007219//Notch signaling pathway;GO:0003208//cardiac ventricle morphogenesis",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0051879//Hsp90 protein binding;GO:0019901//protein kinase binding;GO:0000989//transcription factor binding transcription factor activity;GO:0019899//enzyme binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0042826//histone deacetylase binding;GO:0035257//nuclear hormone receptor binding;GO:0035035//histone acetyltransferase binding,K08268//Renal cell carcinoma;mTOR signaling pathway;Pathways in cancer
3092,186,0,1,0,0,5,37,42,99,0,8,0,HIP1;huntingtin interacting protein 1,GO:0030665//clathrin-coated vesicle membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,"GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006897//endocytosis;GO:0097190//apoptotic signaling pathway;GO:0048268//clathrin coat assembly;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030154//cell differentiation;GO:0042981//regulation of apoptotic process;GO:0006355//regulation of transcription, DNA-templated",GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0030276//clathrin binding,K04559//Huntington's disease
3093,0,84,0,100,105,0,0,0,18,0,0,0,UBE2K;ubiquitin-conjugating enzyme E2K,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K04649//Ubiquitin mediated proteolysis
3094,0,1,4,114,215,31,0,0,59,0,9,0,HINT1;histidine triad nucleotide binding protein 1,GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0000118//histone deacetylase complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0006351//transcription, DNA-templated;GO:0009154//purine ribonucleotide catabolic process;GO:0007165//signal transduction;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006355//regulation of transcription, DNA-templated",GO:0016787//hydrolase activity;GO:0000166//nucleotide binding;GO:0005080//protein kinase C binding,K02089//Chronic myeloid leukemia;Melanoma;Non-small cell lung cancer;T cell receptor signaling pathway;Cell cycle;Bladder cancer;p53 signaling pathway;Glioma;Measles;HTLV-I infection;Pancreatic cancer;Tight junction;Pathways in cancer;Small cell lung cancer
3096,80,12,1,20,86,33,14,0,92,102,1,0,HIVEP1;human immunodeficiency virus type I enhancer binding protein 1,GO:0005634//nucleus;GO:0005739//mitochondrion,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
30968,0,21,0,2,7,0,34,0,14,0,0,0,STOML2;stomatin (EPB72)-like 2,GO:0015629//actin cytoskeleton;GO:0005743//mitochondrial inner membrane;GO:0008180//COP9 signalosome;GO:0042101//T cell receptor complex;GO:0001772//immunological synapse;GO:0019897//extrinsic component of plasma membrane;GO:0045121//membrane raft;GO:0005758//mitochondrial intermembrane space;GO:0005856//cytoskeleton,"GO:0034982//mitochondrial protein processing;GO:0006874//cellular calcium ion homeostasis;GO:0006851//mitochondrial calcium ion transport;GO:0051259//protein oligomerization;GO:0032623//interleukin-2 production;GO:0007005//mitochondrion organization;GO:0090297//positive regulation of mitochondrial DNA replication;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:1990046//stress-induced mitochondrial fusion;GO:0010876//lipid localization;GO:0050852//T cell receptor signaling pathway;GO:1900210//positive regulation of cardiolipin metabolic process;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0010918//positive regulation of mitochondrial membrane potential",GO:0005102//receptor binding;GO:0005515//protein binding;GO:1901612//cardiolipin binding,K03364//Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle
3097,0,47,0,7,18,24,0,0,45,0,10,0,HIVEP2;human immunodeficiency virus type I enhancer binding protein 2,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
3098,0,81,2,61,208,15,9,0,38,0,15,1,HK1;hexokinase 1,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane,GO:0055085//transmembrane transport;GO:0046835//carbohydrate phosphorylation;GO:0015758//glucose transport;GO:0019318//hexose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0005975//carbohydrate metabolic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0001678//cellular glucose homeostasis,GO:0008865//fructokinase activity;GO:0005524//ATP binding;GO:0004340//glucokinase activity;GO:0005515//protein binding;GO:0019158//mannokinase activity,K00844//Type II diabetes mellitus;Fructose and mannose metabolism;Metabolic pathways;Galactose metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Butirosin and neomycin biosynthesis;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Carbohydrate digestion and absorption;Insulin signaling pathway;Microbial metabolism in diverse environments;Streptomycin biosynthesis
3099,70,0,0,20,12,2,59,60,96,236,0,2,HK2;hexokinase 2,GO:0005829//cytosol;GO:0016020//membrane;GO:0005741//mitochondrial outer membrane,GO:0055085//transmembrane transport;GO:0046835//carbohydrate phosphorylation;GO:0015758//glucose transport;GO:0046324//regulation of glucose import;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0007595//lactation;GO:0005975//carbohydrate metabolic process;GO:0008637//apoptotic mitochondrial changes;GO:0051156//glucose 6-phosphate metabolic process;GO:0001678//cellular glucose homeostasis,GO:0019158//mannokinase activity;GO:0008865//fructokinase activity;GO:0005536//glucose binding;GO:0005524//ATP binding;GO:0004340//glucokinase activity,K00844//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Butirosin and neomycin biosynthesis;Amino sugar and nucleotide sugar metabolism;Glycolysis / Gluconeogenesis;Carbohydrate digestion and absorption;Streptomycin biosynthesis;Microbial metabolism in diverse environments;Insulin signaling pathway;Type II diabetes mellitus;Fructose and mannose metabolism;Galactose metabolism;Metabolic pathways
31,283,201,1,151,459,7,38,31,227,1,21,4,ACACA;acetyl-CoA carboxylase alpha,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:2001295//malonyl-CoA biosynthetic process;GO:0044268//multicellular organismal protein metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006084//acetyl-CoA metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0006766//vitamin metabolic process;GO:0006768//biotin metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0055088//lipid homeostasis;GO:0044255//cellular lipid metabolic process;GO:0051289//protein homotetramerization;GO:0001894//tissue homeostasis;GO:0006853//carnitine shuttle;GO:0031325//positive regulation of cellular metabolic process,GO:0003989//acetyl-CoA carboxylase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004075//biotin carboxylase activity,K11262//Adipocytokine signaling pathway;Propanoate metabolism;Pyruvate metabolism;Metabolic pathways;Insulin signaling pathway;Fatty acid biosynthesis
310,4,154,1,86,206,0,0,0,31,0,0,0,ANXA7;annexin A7,GO:0042584//chromaffin granule membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol,GO:0061025//membrane fusion;GO:0006914//autophagy;GO:0008283//cell proliferation;GO:0035176//social behavior;GO:0009992//cellular water homeostasis;GO:0009651//response to salt stress;GO:0051592//response to calcium ion;GO:0030855//epithelial cell differentiation;GO:0008360//regulation of cell shape;GO:0006874//cellular calcium ion homeostasis;GO:0010629//negative regulation of gene expression;GO:0007599//hemostasis;GO:0014070//response to organic cyclic compound,GO:0005178//integrin binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,-
3101,0,0,0,0,0,0,0,2,28,40,7,529,HK3;hexokinase 3 (white cell),GO:0043234//protein complex;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0051156//glucose 6-phosphate metabolic process;GO:0001678//cellular glucose homeostasis;GO:0055085//transmembrane transport;GO:0046835//carbohydrate phosphorylation;GO:0015758//glucose transport;GO:0019318//hexose metabolic process,GO:0019158//mannokinase activity;GO:0042562//hormone binding;GO:0005524//ATP binding;GO:0004340//glucokinase activity;GO:0019899//enzyme binding;GO:0008865//fructokinase activity,K00844//Type II diabetes mellitus;Fructose and mannose metabolism;Metabolic pathways;Galactose metabolism;Glycolysis / Gluconeogenesis;Butirosin and neomycin biosynthesis;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Carbohydrate digestion and absorption;Insulin signaling pathway;Streptomycin biosynthesis;Microbial metabolism in diverse environments
3104,0,0,0,0,0,13,0,0,13,1,0,0,ZBTB48;zinc finger and BTB domain containing 48,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3106,0,20,0,3,0,0,2,0,0,0,16,134,"HLA-B;major histocompatibility complex, class I, B",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0005794//Golgi apparatus;GO:0042612//MHC class I protein complex;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0031901//early endosome membrane,"GO:2001198//regulation of dendritic cell differentiation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0016032//viral process;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0060337//type I interferon signaling pathway;GO:0050776//regulation of immune response;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002667//regulation of T cell anergy;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0006955//immune response;GO:0032655//regulation of interleukin-12 production;GO:0045087//innate immune response;GO:0002486//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006952//defense response;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0032675//regulation of interleukin-6 production;GO:0016045//detection of bacterium",GO:0042605//peptide antigen binding;GO:0005102//receptor binding;GO:0046977//TAP binding;GO:0051087//chaperone binding,K06751//Epstein-Barr virus infection;Antigen processing and presentation;Allograft rejection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Viral myocarditis;Graft-versus-host disease;Type I diabetes mellitus;HTLV-I infection;Endocytosis;Phagosome;Autoimmune thyroid disease
3107,0,22,0,0,23,0,34,0,0,0,28,0,"HLA-C;major histocompatibility complex, class I, C",GO:0042612//MHC class I protein complex;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0031901//early endosome membrane,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0006955//immune response;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0045087//innate immune response;GO:0002486//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0016032//viral process;GO:0060337//type I interferon signaling pathway;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response",GO:0042605//peptide antigen binding;GO:0046977//TAP binding,K06751//Antigen processing and presentation;Epstein-Barr virus infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Graft-versus-host disease;Viral myocarditis;Allograft rejection;Type I diabetes mellitus;Endocytosis;HTLV-I infection;Phagosome;Autoimmune thyroid disease
3108,0,0,0,0,0,0,0,0,13,0,0,0,"HLA-DMA;major histocompatibility complex, class II, DM alpha",GO:0005771//multivesicular body;GO:0031902//late endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex,GO:0016064//immunoglobulin mediated immune response;GO:0045059//positive thymic T cell selection;GO:0048839//inner ear development;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0050778//positive regulation of immune response;GO:0045582//positive regulation of T cell differentiation;GO:0015031//protein transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002503//peptide antigen assembly with MHC class II protein complex,GO:0023026//MHC class II protein complex binding,K06752//Autoimmune thyroid disease;Phagosome;Rheumatoid arthritis;Tuberculosis;Influenza A;Intestinal immune network for IgA production;Viral myocarditis;Systemic lupus erythematosus;Herpes simplex infection;Allograft rejection;Hematopoietic cell lineage;Staphylococcus aureus infection;Epstein-Barr virus infection;HTLV-I infection;Type I diabetes mellitus;Toxoplasmosis;Graft-versus-host disease;Leishmaniasis;Cell adhesion molecules (CAMs);Antigen processing and presentation;Asthma
311,0,78,1,47,43,2,77,1,38,138,6,0,ANXA11;annexin A11,GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0005654//nucleoplasm;GO:0005819//spindle;GO:0045335//phagocytic vesicle;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0016020//membrane,"GO:0006909//phagocytosis;GO:0007109//cytokinesis, completion of separation;GO:0051592//response to calcium ion",GO:0023026//MHC class II protein complex binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008429//phosphatidylethanolamine binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0044548//S100 protein binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K03956//Metabolic pathways;Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K11447//Transcriptional misregulation in cancer
3110,101,0,0,0,15,13,0,28,26,0,0,1,MNX1;motor neuron and pancreas homeobox 1,GO:0005634//nucleus,"GO:0031018//endocrine pancreas development;GO:0021904//dorsal/ventral neural tube patterning;GO:0021520//spinal cord motor neuron cell fate specification;GO:0009791//post-embryonic development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001764//neuron migration;GO:0008045//motor neuron axon guidance;GO:0009653//anatomical structure morphogenesis;GO:0006959//humoral immune response;GO:0006351//transcription, DNA-templated;GO:0021675//nerve development;GO:0060539//diaphragm development",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K08025//Maturity onset diabetes of the young
3111,0,0,0,0,1,0,1,0,33,0,8,0,"HLA-DOA;major histocompatibility complex, class II, DO alpha",GO:0042613//MHC class II protein complex;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0045580//regulation of T cell differentiation;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006955//immune response,GO:0023026//MHC class II protein complex binding;GO:0032395//MHC class II receptor activity,K06752//Systemic lupus erythematosus;Viral myocarditis;Herpes simplex infection;Allograft rejection;Hematopoietic cell lineage;Staphylococcus aureus infection;Epstein-Barr virus infection;Autoimmune thyroid disease;Phagosome;Rheumatoid arthritis;Tuberculosis;Intestinal immune network for IgA production;Influenza A;Toxoplasmosis;Graft-versus-host disease;Leishmaniasis;Cell adhesion molecules (CAMs);Antigen processing and presentation;Asthma;HTLV-I infection;Type I diabetes mellitus
3112,0,0,0,0,0,0,0,0,29,0,0,0,"HLA-DOB;major histocompatibility complex, class II, DO beta",GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0005764//lysosome;GO:0010008//endosome membrane;GO:0016021//integral component of membrane,GO:0006955//immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0002587//negative regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:0007165//signal transduction,GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding,K06752//Asthma;Antigen processing and presentation;Graft-versus-host disease;Toxoplasmosis;Leishmaniasis;Cell adhesion molecules (CAMs);Type I diabetes mellitus;HTLV-I infection;Epstein-Barr virus infection;Staphylococcus aureus infection;Hematopoietic cell lineage;Allograft rejection;Systemic lupus erythematosus;Viral myocarditis;Herpes simplex infection;Intestinal immune network for IgA production;Influenza A;Tuberculosis;Phagosome;Autoimmune thyroid disease;Rheumatoid arthritis
3113,0,18,39,55,198,0,0,0,12,0,202,0,"HLA-DPA1;major histocompatibility complex, class II, DP alpha 1",GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane,GO:0050870//positive regulation of T cell activation;GO:0032729//positive regulation of interferon-gamma production;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation;GO:0071346//cellular response to interferon-gamma;GO:0006955//immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway,GO:0042605//peptide antigen binding;GO:0032395//MHC class II receptor activity,K06752//Type I diabetes mellitus;HTLV-I infection;Antigen processing and presentation;Asthma;Graft-versus-host disease;Leishmaniasis;Toxoplasmosis;Cell adhesion molecules (CAMs);Tuberculosis;Influenza A;Intestinal immune network for IgA production;Phagosome;Autoimmune thyroid disease;Rheumatoid arthritis;Epstein-Barr virus infection;Viral myocarditis;Systemic lupus erythematosus;Herpes simplex infection;Allograft rejection;Hematopoietic cell lineage;Staphylococcus aureus infection
3115,0,14,0,3,29,0,0,0,46,0,0,0,"HLA-DPB1;major histocompatibility complex, class II, DP beta 1",GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0000139//Golgi membrane,GO:0050870//positive regulation of T cell activation;GO:0032729//positive regulation of interferon-gamma production;GO:0042102//positive regulation of T cell proliferation;GO:0031295//T cell costimulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway,GO:0042605//peptide antigen binding,K06752//HTLV-I infection;Type I diabetes mellitus;Cell adhesion molecules (CAMs);Graft-versus-host disease;Toxoplasmosis;Leishmaniasis;Antigen processing and presentation;Asthma;Rheumatoid arthritis;Phagosome;Autoimmune thyroid disease;Tuberculosis;Intestinal immune network for IgA production;Influenza A;Herpes simplex infection;Systemic lupus erythematosus;Viral myocarditis;Staphylococcus aureus infection;Hematopoietic cell lineage;Allograft rejection;Epstein-Barr virus infection
3116,0,0,0,0,0,0,1,0,0,0,2,0,"HLA-DPB2;major histocompatibility complex, class II, DP beta 2 (pseudogene)",-,-,-,K06752//Epstein-Barr virus infection;Systemic lupus erythematosus;Viral myocarditis;Herpes simplex infection;Hematopoietic cell lineage;Staphylococcus aureus infection;Allograft rejection;Tuberculosis;Influenza A;Intestinal immune network for IgA production;Autoimmune thyroid disease;Phagosome;Rheumatoid arthritis;Antigen processing and presentation;Asthma;Leishmaniasis;Graft-versus-host disease;Toxoplasmosis;Cell adhesion molecules (CAMs);Type I diabetes mellitus;HTLV-I infection
3117,41,0,0,0,0,0,0,0,12,0,0,0,"HLA-DQA1;major histocompatibility complex, class II, DQ alpha 1",GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0005765//lysosomal membrane;GO:0030666//endocytic vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0005887//integral component of plasma membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0030669//clathrin-coated endocytic vesicle membrane,GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0031295//T cell costimulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006955//immune response,GO:0042605//peptide antigen binding;GO:0032395//MHC class II receptor activity,K06752//Intestinal immune network for IgA production;Influenza A;Tuberculosis;Autoimmune thyroid disease;Phagosome;Rheumatoid arthritis;Epstein-Barr virus infection;Allograft rejection;Hematopoietic cell lineage;Staphylococcus aureus infection;Systemic lupus erythematosus;Viral myocarditis;Herpes simplex infection;Type I diabetes mellitus;HTLV-I infection;Asthma;Antigen processing and presentation;Graft-versus-host disease;Toxoplasmosis;Leishmaniasis;Cell adhesion molecules (CAMs)
312,0,0,0,0,0,0,0,0,1,0,4,0,ANXA13;annexin A13,GO:0016324//apical plasma membrane;GO:0070382//exocytic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane,GO:0030154//cell differentiation;GO:0042998//positive regulation of Golgi to plasma membrane protein transport;GO:0042997//negative regulation of Golgi to plasma membrane protein transport,GO:0031210//phosphatidylcholine binding;GO:1901611//phosphatidylglycerol binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding,-
3122,0,0,0,0,0,15,0,1,8,0,0,0,"HLA-DRA;major histocompatibility complex, class II, DR alpha",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0030666//endocytic vesicle membrane;GO:0031902//late endosome membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome,GO:0031295//T cell costimulation;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050890//cognition;GO:0002506//polysaccharide assembly with MHC class II protein complex;GO:0002503//peptide antigen assembly with MHC class II protein complex;GO:0006955//immune response;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0032395//MHC class II receptor activity;GO:0042605//peptide antigen binding;GO:0023026//MHC class II protein complex binding,K06752//Influenza A;Intestinal immune network for IgA production;Tuberculosis;Autoimmune thyroid disease;Phagosome;Rheumatoid arthritis;Epstein-Barr virus infection;Allograft rejection;Hematopoietic cell lineage;Staphylococcus aureus infection;Viral myocarditis;Systemic lupus erythematosus;Herpes simplex infection;Type I diabetes mellitus;HTLV-I infection;Asthma;Antigen processing and presentation;Leishmaniasis;Graft-versus-host disease;Toxoplasmosis;Cell adhesion molecules (CAMs)
3123,0,0,0,0,0,10,0,0,7,124,0,0,"HLA-DRB1;major histocompatibility complex, class II, DR beta 1",GO:0032588//trans-Golgi network membrane;GO:0031902//late endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0030658//transport vesicle membrane;GO:0042613//MHC class II protein complex,GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production;GO:0032673//regulation of interleukin-4 production;GO:0042088//T-helper 1 type immune response;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0031295//T cell costimulation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0006955//immune response;GO:0002437//inflammatory response to antigenic stimulus;GO:0051262//protein tetramerization;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042130//negative regulation of T cell proliferation;GO:2001179//regulation of interleukin-10 secretion;GO:0002506//polysaccharide assembly with MHC class II protein complex;GO:0002503//peptide antigen assembly with MHC class II protein complex,GO:0032395//MHC class II receptor activity;GO:0023026//MHC class II protein complex binding;GO:0042605//peptide antigen binding,K06752//Rheumatoid arthritis;Phagosome;Autoimmune thyroid disease;Intestinal immune network for IgA production;Influenza A;Tuberculosis;Staphylococcus aureus infection;Hematopoietic cell lineage;Allograft rejection;Herpes simplex infection;Systemic lupus erythematosus;Viral myocarditis;Epstein-Barr virus infection;HTLV-I infection;Type I diabetes mellitus;Cell adhesion molecules (CAMs);Toxoplasmosis;Graft-versus-host disease;Leishmaniasis;Asthma;Antigen processing and presentation
3125,0,0,0,0,0,0,27,0,13,0,0,0,"HLA-DRB3;major histocompatibility complex, class II, DR beta 3",GO:0032588//trans-Golgi network membrane;GO:0030666//endocytic vesicle membrane;GO:0031902//late endosome membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042130//negative regulation of T cell proliferation;GO:2001179//regulation of interleukin-10 secretion;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0007165//signal transduction;GO:0006955//immune response;GO:0002437//inflammatory response to antigenic stimulus;GO:0051262//protein tetramerization;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0032673//regulation of interleukin-4 production;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042088//T-helper 1 type immune response;GO:0031295//T cell costimulation;GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production,GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0032395//MHC class II receptor activity,K06752//Cell adhesion molecules (CAMs);Graft-versus-host disease;Leishmaniasis;Toxoplasmosis;Asthma;Antigen processing and presentation;HTLV-I infection;Type I diabetes mellitus;Hematopoietic cell lineage;Staphylococcus aureus infection;Allograft rejection;Herpes simplex infection;Viral myocarditis;Systemic lupus erythematosus;Epstein-Barr virus infection;Rheumatoid arthritis;Phagosome;Autoimmune thyroid disease;Intestinal immune network for IgA production;Influenza A;Tuberculosis
3127,0,0,1,0,0,0,0,0,0,0,0,0,"HLA-DRB5;major histocompatibility complex, class II, DR beta 5",GO:0005765//lysosomal membrane;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0032588//trans-Golgi network membrane;GO:0030666//endocytic vesicle membrane;GO:0005615//extracellular space,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042130//negative regulation of T cell proliferation;GO:2001179//regulation of interleukin-10 secretion;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0032673//regulation of interleukin-4 production;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042088//T-helper 1 type immune response;GO:0031295//T cell costimulation;GO:0016045//detection of bacterium;GO:0032689//negative regulation of interferon-gamma production;GO:0006955//immune response;GO:0002437//inflammatory response to antigenic stimulus;GO:0051262//protein tetramerization;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response,GO:0042605//peptide antigen binding,K06752//HTLV-I infection;Type I diabetes mellitus;Cell adhesion molecules (CAMs);Graft-versus-host disease;Toxoplasmosis;Leishmaniasis;Antigen processing and presentation;Asthma;Rheumatoid arthritis;Phagosome;Autoimmune thyroid disease;Tuberculosis;Influenza A;Intestinal immune network for IgA production;Herpes simplex infection;Viral myocarditis;Systemic lupus erythematosus;Staphylococcus aureus infection;Hematopoietic cell lineage;Allograft rejection;Epstein-Barr virus infection
313,0,0,0,0,0,17,25,0,11,0,0,0,AOAH;acyloxyacyl hydrolase (neutrophil),GO:0005576//extracellular region,GO:0006954//inflammatory response;GO:0006629//lipid metabolic process;GO:0050728//negative regulation of inflammatory response;GO:0008653//lipopolysaccharide metabolic process,GO:0004465//lipoprotein lipase activity;GO:0003824//catalytic activity;GO:0050528//acyloxyacyl hydrolase activity,-
3131,0,0,0,0,0,0,0,75,72,0,0,0,HLF;hepatic leukemia factor,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0035914//skeletal muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding,K09057//Circadian rhythm - fly
3133,0,0,0,0,0,0,2,0,0,0,0,0,"HLA-E;major histocompatibility complex, class I, E",GO:0012507//ER to Golgi transport vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0031901//early endosome membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0042612//MHC class I protein complex;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0060337//type I interferon signaling pathway;GO:0002476//antigen processing and presentation of endogenous peptide antigen via MHC class Ib;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response;GO:0002717//positive regulation of natural killer cell mediated immunity;GO:0042270//protection from natural killer cell mediated cytotoxicity;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway",GO:0042288//MHC class I protein binding;GO:0042605//peptide antigen binding,K06751//Endocytosis;HTLV-I infection;Autoimmune thyroid disease;Phagosome;Type I diabetes mellitus;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Herpes simplex infection;Viral myocarditis;Graft-versus-host disease;Allograft rejection;Antigen processing and presentation;Epstein-Barr virus infection
3134,0,0,0,0,0,1,0,0,12,0,0,0,"HLA-F;major histocompatibility complex, class I, F",GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0042612//MHC class I protein complex;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane,"GO:0060337//type I interferon signaling pathway;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0019221//cytokine-mediated signaling pathway",GO:0046979//TAP2 binding;GO:0046978//TAP1 binding;GO:0042605//peptide antigen binding,K06751//Endocytosis;HTLV-I infection;Phagosome;Autoimmune thyroid disease;Type I diabetes mellitus;Allograft rejection;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Graft-versus-host disease;Viral myocarditis;Epstein-Barr virus infection;Antigen processing and presentation
3135,0,0,0,0,0,0,0,2,0,0,2,0,"HLA-G;major histocompatibility complex, class I, G",GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0042612//MHC class I protein complex;GO:0031901//early endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane,"GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0060337//type I interferon signaling pathway;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response;GO:2001199//negative regulation of dendritic cell differentiation;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0002666//positive regulation of T cell tolerance induction;GO:0042130//negative regulation of T cell proliferation;GO:0006968//cellular defense response;GO:0032735//positive regulation of interleukin-12 production;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0002767//immune response-inhibiting cell surface receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway",GO:0042803//protein homodimerization activity;GO:0042605//peptide antigen binding;GO:0005102//receptor binding,K06751//Type I diabetes mellitus;Autoimmune thyroid disease;Phagosome;HTLV-I infection;Endocytosis;Antigen processing and presentation;Epstein-Barr virus infection;Graft-versus-host disease;Viral myocarditis;Herpes simplex infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Allograft rejection
3136,0,0,0,0,0,0,0,0,12,0,0,0,"HLA-H;major histocompatibility complex, class I, H (pseudogene)",GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0042612//MHC class I protein complex,GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006955//immune response;GO:0001916//positive regulation of T cell mediated cytotoxicity,GO:0042605//peptide antigen binding;GO:0030881//beta-2-microglobulin binding,K06751//Type I diabetes mellitus;HTLV-I infection;Endocytosis;Phagosome;Autoimmune thyroid disease;Antigen processing and presentation;Epstein-Barr virus infection;Herpes simplex infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Viral myocarditis;Allograft rejection
3137,0,0,0,0,0,0,0,0,6,0,0,0,"HLA-J;major histocompatibility complex, class I, J (pseudogene)",-,-,-,K06751//Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Graft-versus-host disease;Viral myocarditis;Allograft rejection;Antigen processing and presentation;Epstein-Barr virus infection;HTLV-I infection;Endocytosis;Autoimmune thyroid disease;Phagosome;Type I diabetes mellitus
3139,0,0,2,0,0,0,0,0,18,0,0,0,"HLA-L;major histocompatibility complex, class I, L (pseudogene)",-,-,-,K06751//Endocytosis;HTLV-I infection;Autoimmune thyroid disease;Phagosome;Type I diabetes mellitus;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Viral myocarditis;Graft-versus-host disease;Allograft rejection;Antigen processing and presentation;Epstein-Barr virus infection
314,0,0,0,0,0,0,0,0,22,0,0,0,"AOC2;amine oxidase, copper containing 2 (retina-specific)",GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0009308//amine metabolic process;GO:0006584//catecholamine metabolic process;GO:0007601//visual perception;GO:0055114//oxidation-reduction process,GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity;GO:0005507//copper ion binding;GO:0008131//primary amine oxidase activity;GO:0009055//electron carrier activity;GO:0048038//quinone binding,"K00276//Tyrosine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;Metabolic pathways;beta-Alanine metabolism;Phenylalanine metabolism;Isoquinoline alkaloid biosynthesis;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites"
3140,0,0,0,0,0,28,61,0,22,0,0,0,"MR1;major histocompatibility complex, class I-related",GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0042612//MHC class I protein complex,GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0006955//immune response;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I,GO:0042605//peptide antigen binding;GO:0032393//MHC class I receptor activity,K06751//Antigen processing and presentation;Epstein-Barr virus infection;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Herpes simplex infection;Graft-versus-host disease;Viral myocarditis;Allograft rejection;Type I diabetes mellitus;HTLV-I infection;Endocytosis;Autoimmune thyroid disease;Phagosome
3141,0,53,2,43,101,14,8,0,57,0,11,0,HLCS;holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase),GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0000785//chromatin;GO:0016363//nuclear matrix;GO:0005652//nuclear lamina;GO:0005737//cytoplasm,GO:0016570//histone modification;GO:0070781//response to biotin;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0071110//histone biotinylation;GO:0006766//vitamin metabolic process;GO:0008283//cell proliferation;GO:0006768//biotin metabolic process,GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0004078//biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity;GO:0004080//biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity;GO:0004077//biotin-[acetyl-CoA-carboxylase] ligase activity;GO:0004079//biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0009374//biotin binding,K01942//Biotin metabolism;Metabolic pathways
3142,0,0,0,0,0,0,0,0,6,1,0,90,HLX;H2.0-like homeobox,GO:0005634//nucleus,"GO:0001889//liver development;GO:0048557//embryonic digestive tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0046622//positive regulation of organ growth;GO:0048484//enteric nervous system development;GO:0006351//transcription, DNA-templated;GO:0007519//skeletal muscle tissue development",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
3145,171,0,0,0,6,0,2,69,0,0,11,0,HMBS;hydroxymethylbilane synthase,GO:0005829//cytosol,GO:0006778//porphyrin-containing compound metabolic process;GO:0006783//heme biosynthetic process;GO:0018160//peptidyl-pyrromethane cofactor linkage;GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process,GO:0004418//hydroxymethylbilane synthase activity,K01749//Methane metabolism;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Porphyrin and chlorophyll metabolism;Microbial metabolism in diverse environments;Metabolic pathways;Propanoate metabolism;Pyruvate metabolism
3146,0,114,2,187,395,16,0,0,29,0,0,0,HMGB1;high mobility group box 1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0000793//condensed chromosome;GO:0005576//extracellular region;GO:0017053//transcriptional repressor complex,"GO:0006288//base-excision repair, DNA ligation;GO:0031175//neuron projection development;GO:0051103//DNA ligation involved in DNA repair;GO:0050918//positive chemotaxis;GO:0045087//innate immune response;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002437//inflammatory response to antigenic stimulus;GO:0043388//positive regulation of DNA binding;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0017055//negative regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006310//DNA recombination;GO:0002407//dendritic cell chemotaxis;GO:2000426//negative regulation of apoptotic cell clearance;GO:0033151//V(D)J recombination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0006265//DNA topological change;GO:0006309//apoptotic DNA fragmentation;GO:0006915//apoptotic process","GO:0008301//DNA binding, bending;GO:0003697//single-stranded DNA binding;GO:0070491//repressing transcription factor binding;GO:0003690//double-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0042056//chemoattractant activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005125//cytokine activity;GO:0008134//transcription factor binding;GO:0050786//RAGE receptor binding",K10802//Base excision repair
3148,0,13,0,8,0,0,0,0,0,0,0,0,HMGB2;high mobility group box 2,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0000793//condensed chromosome;GO:0005615//extracellular space,"GO:0032075//positive regulation of nuclease activity;GO:0006288//base-excision repair, DNA ligation;GO:0060326//cell chemotaxis;GO:0051103//DNA ligation involved in DNA repair;GO:0006334//nucleosome assembly;GO:0050918//positive chemotaxis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001938//positive regulation of endothelial cell proliferation;GO:0006325//chromatin organization;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0045648//positive regulation of erythrocyte differentiation;GO:0007289//spermatid nucleus differentiation;GO:0043388//positive regulation of DNA binding;GO:0071222//cellular response to lipopolysaccharide;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0033151//V(D)J recombination;GO:0048545//response to steroid hormone;GO:0006265//DNA topological change;GO:0008584//male gonad development;GO:0006309//apoptotic DNA fragmentation;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated","GO:0003697//single-stranded DNA binding;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0008301//DNA binding, bending;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042056//chemoattractant activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0050786//RAGE receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003684//damaged DNA binding",-
3150,2,0,0,0,2,0,0,268,0,0,10,1,HMGN1;high mobility group nucleosome binding domain 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000785//chromatin,"GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010224//response to UV-B;GO:0050678//regulation of epithelial cell proliferation;GO:0000720//pyrimidine dimer repair by nucleotide-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0010225//response to UV-C;GO:0006325//chromatin organization",GO:0003677//DNA binding;GO:0031492//nucleosomal DNA binding,K11299//Herpes simplex infection
3151,1,35,1,52,126,0,0,42,8,0,0,0,HMGN2;high mobility group nucleosomal binding domain 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000785//chromatin,-,GO:0031492//nucleosomal DNA binding;GO:0044822//poly(A) RNA binding,-
3155,0,43,20,27,76,17,0,1,44,0,0,0,HMGCL;3-hydroxymethyl-3-methylglutaryl-CoA lyase,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome,GO:0042594//response to starvation;GO:0007584//response to nutrient;GO:0051262//protein tetramerization;GO:0070542//response to fatty acid;GO:0044255//cellular lipid metabolic process;GO:0006552//leucine catabolic process;GO:0006637//acyl-CoA metabolic process;GO:0046951//ketone body biosynthetic process;GO:0007005//mitochondrion organization;GO:0001889//liver development;GO:0044281//small molecule metabolic process,GO:0030145//manganese ion binding;GO:0000287//magnesium ion binding;GO:0005102//receptor binding;GO:0000062//fatty-acyl-CoA binding;GO:0031406//carboxylic acid binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0004419//hydroxymethylglutaryl-CoA lyase activity,"K01640//Peroxisome;Geraniol degradation;Synthesis and degradation of ketone bodies;Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;Metabolic pathways;Butanoate metabolism"
3156,0,0,0,9,18,0,59,0,44,0,19,0,HMGCR;3-hydroxy-3-methylglutaryl-CoA reductase,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005778//peroxisomal membrane;GO:0005789//endoplasmic reticulum membrane,GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051262//protein tetramerization;GO:0061045//negative regulation of wound healing;GO:0045471//response to ethanol;GO:0007568//aging;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0008542//visual learning;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0045445//myoblast differentiation;GO:0045908//negative regulation of vasodilation;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process;GO:0006743//ubiquinone metabolic process;GO:0008299//isoprenoid biosynthetic process;GO:0043407//negative regulation of MAP kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0015936//coenzyme A metabolic process,GO:0042282//hydroxymethylglutaryl-CoA reductase activity;GO:0050662//coenzyme binding;GO:0070402//NADPH binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004420//hydroxymethylglutaryl-CoA reductase (NADPH) activity,K00021//Metabolic pathways;Terpenoid backbone biosynthesis;Biosynthesis of secondary metabolites;Bile secretion
3157,83,69,3,193,710,0,31,0,0,3,2,0,HMGCS1;3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble),GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0001889//liver development;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0042493//response to drug;GO:0044255//cellular lipid metabolic process;GO:0007420//brain development;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0033197//response to vitamin E;GO:0071397//cellular response to cholesterol;GO:0001101//response to acid chemical;GO:0009645//response to low light intensity stimulus;GO:0046690//response to tellurium ion;GO:0055094//response to lipoprotein particle;GO:0008584//male gonad development;GO:0014074//response to purine-containing compound;GO:0006695//cholesterol biosynthetic process;GO:0008299//isoprenoid biosynthetic process,GO:0016853//isomerase activity;GO:0008144//drug binding;GO:0004421//hydroxymethylglutaryl-CoA synthase activity;GO:0043177//organic acid binding;GO:0042803//protein homodimerization activity,"K01641//PPAR signaling pathway;Butanoate metabolism;Terpenoid backbone biosynthesis;Biosynthesis of secondary metabolites;Synthesis and degradation of ketone bodies;Valine, leucine and isoleucine degradation;Metabolic pathways;Lipoic acid metabolism"
3158,0,35,0,13,78,0,15,0,13,114,1,0,HMGCS2;3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial),GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0046951//ketone body biosynthetic process;GO:0008299//isoprenoid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006695//cholesterol biosynthetic process,GO:0004421//hydroxymethylglutaryl-CoA synthase activity,"K01641//Synthesis and degradation of ketone bodies;Biosynthesis of secondary metabolites;PPAR signaling pathway;Terpenoid backbone biosynthesis;Butanoate metabolism;Lipoic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways"
3159,0,22,13,0,1,1,4,0,23,0,0,0,HMGA1;high mobility group AT-hook 1,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0035985//senescence-associated heterochromatin focus;GO:0005925//focal adhesion,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090402//oncogene-induced cell senescence;GO:2000774//positive regulation of cellular senescence;GO:0035986//senescence-associated heterochromatin focus assembly;GO:0016032//viral process;GO:0006284//base-excision repair;GO:0006268//DNA unwinding involved in DNA replication;GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0009615//response to virus;GO:0006461//protein complex assembly;GO:0006337//nucleosome disassembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031936//negative regulation of chromatin silencing;GO:0006355//regulation of transcription, DNA-templated;GO:0075713//establishment of integrated proviral latency",GO:0003677//DNA binding;GO:0003680//AT DNA binding;GO:0042974//retinoic acid receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0042975//peroxisome proliferator activated receptor binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046965//retinoid X receptor binding,-
316,0,49,2,88,188,30,10,25,71,0,0,0,AOX1;aldehyde oxidase 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0042816//vitamin B6 metabolic process;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0006954//inflammatory response,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron carrier activity;GO:0043546//molybdopterin cofactor binding;GO:0004031//aldehyde oxidase activity;GO:0051287//NAD binding;GO:0008762//UDP-N-acetylmuramate dehydrogenase activity;GO:0005506//iron ion binding;GO:0004854//xanthine dehydrogenase activity","K00157//Tryptophan metabolism;Nicotinate and nicotinamide metabolism;Vitamin B6 metabolism;Tyrosine metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Valine, leucine and isoleucine degradation"
3161,0,0,0,0,0,0,0,0,51,4,0,0,HMMR;hyaluronan-mediated motility receptor (RHAMM),GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0005975//carbohydrate metabolic process;GO:0030214//hyaluronan catabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030212//hyaluronan metabolic process,GO:0005540//hyaluronic acid binding,K06267//ECM-receptor interaction
3162,170,0,0,0,0,0,0,0,16,0,9,0,HMOX1;heme oxygenase (decycling) 1,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0006788//heme oxidation;GO:0071243//cellular response to arsenic-containing substance;GO:0006979//response to oxidative stress;GO:0006778//porphyrin-containing compound metabolic process;GO:0042167//heme catabolic process;GO:0035094//response to nicotine;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0031670//cellular response to nutrient;GO:0043524//negative regulation of neuron apoptotic process;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0035556//intracellular signal transduction;GO:0014806//smooth muscle hyperplasia;GO:0042542//response to hydrogen peroxide;GO:0032764//negative regulation of mast cell cytokine production;GO:0001525//angiogenesis;GO:0002246//wound healing involved in inflammatory response;GO:0001935//endothelial cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0034383//low-density lipoprotein particle clearance;GO:0043627//response to estrogen;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0008217//regulation of blood pressure;GO:0034101//erythrocyte homeostasis;GO:0002686//negative regulation of leukocyte migration;GO:0045909//positive regulation of vasodilation;GO:0043392//negative regulation of DNA binding;GO:0045765//regulation of angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0055085//transmembrane transport;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0055072//iron ion homeostasis;GO:0043305//negative regulation of mast cell degranulation;GO:0071276//cellular response to cadmium ion;GO:0007588//excretion;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071456//cellular response to hypoxia;GO:0006879//cellular iron ion homeostasis;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045766//positive regulation of angiogenesis;GO:0051260//protein homooligomerization,GO:0004871//signal transducer activity;GO:0004630//phospholipase D activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004392//heme oxygenase (decyclizing) activity;GO:0019899//enzyme binding,K00510//Mineral absorption;Porphyrin and chlorophyll metabolism
3163,0,16,28,12,26,5,0,0,1,0,19,0,HMOX2;heme oxygenase (decycling) 2,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006879//cellular iron ion homeostasis;GO:0044281//small molecule metabolic process;GO:0042167//heme catabolic process;GO:0006778//porphyrin-containing compound metabolic process;GO:0001666//response to hypoxia;GO:0006788//heme oxidation;GO:0055085//transmembrane transport;GO:0006979//response to oxidative stress,GO:0004392//heme oxygenase (decyclizing) activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K00510//Mineral absorption;Porphyrin and chlorophyll metabolism
3164,0,0,1,0,0,1,26,36,0,0,8,0,"NR4A1;nuclear receptor subfamily 4, group A, member 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,GO:0043065//positive regulation of apoptotic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035767//endothelial cell chemotaxis;GO:0043401//steroid hormone mediated signaling pathway;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010467//gene expression;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0035914//skeletal muscle cell differentiation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K04465//MAPK signaling pathway
3166,0,0,0,0,0,0,0,0,0,0,0,43,HMX1;H6 family homeobox 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,-
3167,17,0,0,0,0,0,0,0,0,0,0,0,HMX2;H6 family homeobox 2,GO:0005634//nucleus,"GO:0007420//brain development;GO:0006355//regulation of transcription, DNA-templated;GO:0042472//inner ear morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
3169,0,12,17,95,372,0,0,2,8,0,52,0,FOXA1;forkhead box A1,GO:0005634//nucleus;GO:0005902//microvillus,"GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060487//lung epithelial cell differentiation;GO:0060740//prostate gland epithelium morphogenesis;GO:0006338//chromatin remodeling;GO:0045880//positive regulation of smoothened signaling pathway;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0042445//hormone metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0060738//epithelial-mesenchymal signaling involved in prostate gland development;GO:0060743//epithelial cell maturation involved in prostate gland development;GO:0032355//response to estradiol;GO:0045666//positive regulation of neuron differentiation;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0006351//transcription, DNA-templated;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0048665//neuron fate specification;GO:0045931//positive regulation of mitotic cell cycle;GO:0042593//glucose homeostasis;GO:0021904//dorsal/ventral neural tube patterning;GO:0060741//prostate gland stromal morphogenesis",GO:0019904//protein domain specific binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding,-
317,43,0,0,1,0,53,3,0,53,0,24,0,APAF1;apoptotic peptidase activating factor 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0043293//apoptosome;GO:0005634//nucleus,GO:0001843//neural tube closure;GO:0042981//regulation of apoptotic process;GO:1902510//regulation of apoptotic DNA fragmentation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0072432//response to G1 DNA damage checkpoint signaling;GO:0007399//nervous system development;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0030900//forebrain development;GO:0006915//apoptotic process;GO:0051402//neuron apoptotic process,GO:0043531//ADP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0042802//identical protein binding,K02084//p53 signaling pathway;Apoptosis;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;Tuberculosis;Legionellosis;Small cell lung cancer;Huntington's disease;Parkinson's disease
3170,102,0,0,0,0,0,9,0,35,0,0,0,FOXA2;forkhead box A2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0019218//regulation of steroid metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045880//positive regulation of smoothened signaling pathway;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0006366//transcription from RNA polymerase II promoter;GO:0033132//negative regulation of glucokinase activity;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0061448//connective tissue development;GO:0060487//lung epithelial cell differentiation;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0030193//regulation of blood coagulation;GO:0001701//in utero embryonic development;GO:0021904//dorsal/ventral neural tube patterning;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090009//primitive streak formation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0023019//signal transduction involved in regulation of gene expression;GO:0001705//ectoderm formation;GO:0045665//negative regulation of neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:2000543//positive regulation of gastrulation;GO:0016568//chromatin modification;GO:0070741//response to interleukin-6;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0031018//endocrine pancreas development;GO:0008344//adult locomotory behavior;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0040019//positive regulation of embryonic development;GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0048468//cell development;GO:0071542//dopaminergic neuron differentiation;GO:0048665//neuron fate specification;GO:0032525//somite rostral/caudal axis specification;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0021533//cell differentiation in hindbrain",GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0019904//protein domain specific binding,K08035//Maturity onset diabetes of the young
3171,0,0,0,0,0,29,12,0,13,0,1,318,FOXA3;forkhead box A3,GO:0005634//nucleus,"GO:0009267//cellular response to starvation;GO:0016568//chromatin modification;GO:0001678//cellular glucose homeostasis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031018//endocrine pancreas development;GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0006351//transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0044212//transcription regulatory region DNA binding,K08038//Maturity onset diabetes of the young
3172,0,0,0,0,0,12,41,0,20,0,0,0,"HNF4A;hepatocyte nuclear factor 4, alpha",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0019216//regulation of lipid metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0006591//ornithine metabolic process;GO:0030308//negative regulation of cell growth;GO:0023019//signal transduction involved in regulation of gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050796//regulation of insulin secretion;GO:0006805//xenobiotic metabolic process;GO:0060395//SMAD protein signal transduction;GO:0009749//response to glucose;GO:0045893//positive regulation of transcription, DNA-templated;GO:0055088//lipid homeostasis;GO:0006629//lipid metabolic process;GO:0042593//glucose homeostasis;GO:0060398//regulation of growth hormone receptor signaling pathway;GO:0010470//regulation of gastrulation;GO:0043401//steroid hormone mediated signaling pathway;GO:0007596//blood coagulation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0070328//triglyceride homeostasis;GO:0055091//phospholipid homeostasis;GO:0007548//sex differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000189//positive regulation of cholesterol homeostasis;GO:0031018//endocrine pancreas development;GO:0030522//intracellular receptor signaling pathway",GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005102//receptor binding;GO:0005504//fatty acid binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding,K07292//Maturity onset diabetes of the young
3174,0,0,0,0,5,19,0,0,16,0,8,0,"HNF4G;hepatocyte nuclear factor 4, gamma",GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031018//endocrine pancreas development;GO:0030522//intracellular receptor signaling pathway",GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,K08037//Maturity onset diabetes of the young
3175,0,0,0,0,0,10,0,48,22,0,0,0,ONECUT1;one cut homeobox 1,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0030183//B cell differentiation;GO:0031018//endocrine pancreas development;GO:0002064//epithelial cell development;GO:0001889//liver development;GO:0006006//glucose metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0006351//transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042384//cilium assembly;GO:0001952//regulation of cell-matrix adhesion;GO:0030335//positive regulation of cell migration;GO:0007492//endoderm development",GO:0003677//DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K08026//Maturity onset diabetes of the young
3176,0,0,0,19,0,0,20,3,8,0,0,0,HNMT;histamine N-methyltransferase,GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006972//hyperosmotic response;GO:0007420//brain development;GO:0014075//response to amine;GO:0007585//respiratory gaseous exchange;GO:0070555//response to interleukin-1;GO:0002347//response to tumor cell;GO:0051384//response to glucocorticoid;GO:0042220//response to cocaine;GO:0032259//methylation,GO:0046539//histamine N-methyltransferase activity,K00546//Histidine metabolism
317649,0,6,21,40,158,7,0,15,50,0,9,0,EIF4E3;eukaryotic translation initiation factor 4E family member 3,GO:0005845//mRNA cap binding complex;GO:0005829//cytosol,GO:0006413//translational initiation;GO:0006417//regulation of translation;GO:0019221//cytokine-mediated signaling pathway,GO:0003743//translation initiation factor activity,K03259//Insulin signaling pathway;mTOR signaling pathway;RNA transport
317662,0,0,0,11,29,0,0,84,8,0,3,0,"FAM149B1;family with sequence similarity 149, member B1",-,-,-,-
317671,0,0,0,0,12,16,0,0,7,0,0,0,RFESD;Rieske (Fe-S) domain containing,-,GO:0055114//oxidation-reduction process,"GO:0046872//metal ion binding;GO:0016491//oxidoreductase activity;GO:0051537//2 iron, 2 sulfur cluster binding",-
317705,0,0,0,0,0,8,0,0,31,0,0,0,VN1R5;vomeronasal 1 receptor 5 (gene/pseudogene),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0019236//response to pheromone,GO:0016503//pheromone receptor activity,-
317716,0,0,0,0,0,15,0,0,0,47,3,0,"BPIFA4P;BPI fold containing family A, member 4, pseudogene",-,-,-,-
317719,0,0,0,0,0,0,32,0,0,0,7,0,KLHL10;kelch-like family member 10,GO:0005737//cytoplasm,GO:0007286//spermatid development;GO:0000902//cell morphogenesis;GO:0009566//fertilization;GO:0008584//male gonad development;GO:0048873//homeostasis of number of cells within a tissue;GO:0016567//protein ubiquitination;GO:0048808//male genitalia morphogenesis,-,-
317749,0,0,0,0,16,15,16,0,14,0,0,0,DHRS4L2;dehydrogenase/reductase (SDR family) member 4 like 2,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K11147//Retinol metabolism;Peroxisome;Metabolic pathways;K11148//Metabolic pathways;Retinol metabolism
317754,0,0,0,0,0,0,0,0,13,0,0,0,"POTED;POTE ankyrin domain family, member D",GO:0005886//plasma membrane,-,-,-
317760,0,0,0,0,0,16,0,0,42,0,0,0,ADAM20P1;ADAM metallopeptidase domain 20 pseudogene 1,-,-,-,-
317761,69,0,0,0,0,0,0,0,33,0,12,0,C14orf39;chromosome 14 open reading frame 39,-,GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0007275//multicellular organismal development,-,-
317762,1,35,0,34,68,17,2,73,24,0,5,0,CCDC85C;coiled-coil domain containing 85C,GO:0043296//apical junction complex;GO:0005923//tight junction,GO:0021987//cerebral cortex development,-,-
317772,0,0,0,13,0,0,0,0,18,0,7,0,"HIST2H2AB;histone cluster 2, H2ab",GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome;GO:0005634//nucleus,-,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11251//Alcoholism;Systemic lupus erythematosus
317781,0,0,0,1,11,14,13,69,49,131,0,447,DDX51;DEAD (Asp-Glu-Ala-Asp) box polypeptide 51,GO:0005730//nucleolus;GO:0016020//membrane,GO:0006200//ATP catabolic process;GO:0006364//rRNA processing,GO:0005524//ATP binding;GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding,-
3178,0,39,1,11,39,18,20,0,0,0,0,0,HNRNPA1;heterogeneous nuclear ribonucleoprotein A1,GO:0005681//spliceosomal complex;GO:0070062//extracellular vesicular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0008219//cell death;GO:0016032//viral process;GO:0006405//RNA export from nucleus;GO:0051028//mRNA transport;GO:0051170//nuclear import;GO:0000398//mRNA splicing, via spliceosome;GO:0051168//nuclear export;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006397//mRNA processing",GO:0003723//RNA binding;GO:0003727//single-stranded RNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K12741//Spliceosome
318,0,0,56,18,34,0,0,0,16,0,0,0,NUDT2;nudix (nucleoside diphosphate linked moiety X)-type motif 2,GO:0005739//mitochondrion,GO:0006915//apoptotic process;GO:0006139//nucleobase-containing compound metabolic process,GO:0008803//bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity;GO:0004081//bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity;GO:0005525//GTP binding,K01518//Pyrimidine metabolism;Purine metabolism
3181,0,297,31,220,1119,36,29,0,0,0,10,38,HNRNPA2B1;heterogeneous nuclear ribonucleoprotein A2/B1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex,"GO:0050658//RNA transport;GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0043047//single-stranded telomeric DNA binding;GO:0097157//pre-mRNA intronic binding;GO:0003723//RNA binding,-
3182,0,17,2,25,226,0,2,0,36,0,9,0,HNRNPAB;heterogeneous nuclear ribonucleoprotein A/B,GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001837//epithelial to mesenchymal transition",GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3183,0,366,33,158,511,9,5,0,40,0,0,0,HNRNPC;heterogeneous nuclear ribonucleoprotein C (C1/C2),GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0043044//ATP-dependent chromatin remodeling;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0001649//osteoblast differentiation;GO:0000398//mRNA splicing, via spliceosome",GO:0003730//mRNA 3'-UTR binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008266//poly(U) RNA binding;GO:0042802//identical protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003723//RNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding,K12884//Spliceosome
3184,0,0,0,22,78,0,13,0,0,0,0,0,"HNRNPD;heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0097167//circadian regulation of translation;GO:0008380//RNA splicing;GO:0043488//regulation of mRNA stability;GO:0042752//regulation of circadian rhythm;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006401//RNA catabolic process;GO:0006396//RNA processing;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045727//positive regulation of translation",GO:0003723//RNA binding;GO:0042162//telomeric DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
3185,108,111,1,64,263,0,22,48,0,13,19,0,HNRNPF;heterogeneous nuclear ribonucleoprotein F,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006396//RNA processing;GO:0043484//regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003727//single-stranded RNA binding;GO:0017025//TBP-class protein binding;GO:0003723//RNA binding,-
3187,0,21,0,16,120,0,0,0,25,0,0,0,HNRNPH1;heterogeneous nuclear ribonucleoprotein H1 (H),GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006396//RNA processing;GO:0043484//regulation of RNA splicing;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0008266//poly(U) RNA binding;GO:0003723//RNA binding,-
3189,0,0,0,31,68,30,0,0,6,0,0,0,HNRNPH3;heterogeneous nuclear ribonucleoprotein H3 (2H9),GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0030855//epithelial cell differentiation;GO:0008380//RNA splicing;GO:0006396//RNA processing;GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
319,0,0,0,0,0,3,59,0,2,0,0,0,APOF;apolipoprotein F,GO:0034362//low-density lipoprotein particle;GO:0005576//extracellular region;GO:0034364//high-density lipoprotein particle,GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process;GO:0033344//cholesterol efflux;GO:0006629//lipid metabolic process,GO:0005319//lipid transporter activity;GO:0005102//receptor binding;GO:0015485//cholesterol binding,K14209//Protein digestion and absorption;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
3190,0,214,1,103,579,0,0,0,38,0,9,0,HNRNPK;heterogeneous nuclear ribonucleoprotein K,GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0002102//podosome;GO:0042995//cell projection;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0006396//RNA processing;GO:0016032//viral process;GO:0010988//regulation of low-density lipoprotein particle clearance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045716//positive regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0007165//signal transduction;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0072369//regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003723//RNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003697//single-stranded DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12886//Spliceosome;Herpes simplex infection
3191,0,40,0,25,74,35,20,3,3,0,5,277,HNRNPL;heterogeneous nuclear ribonucleoprotein L,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0045120//pronucleus;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0006396//RNA processing",GO:0044212//transcription regulatory region DNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
319100,70,0,0,0,0,0,0,0,0,0,0,0,TAAR6;trace amine associated receptor 6,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0001594//trace-amine receptor activity,K05051//Neuroactive ligand-receptor interaction
319101,0,0,0,0,0,0,0,0,3,0,0,0,KRT73;keratin 73,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
3192,0,92,3,137,437,31,1,0,68,0,0,0,HNRNPU;heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A),GO:0070937//CRD-mediated mRNA stability complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0009986//cell surface;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0006396//RNA processing;GO:0001649//osteoblast differentiation;GO:0000398//mRNA splicing, via spliceosome;GO:0070934//CRD-mediated mRNA stabilization;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,K12888//Spliceosome
3195,136,8,0,0,0,0,0,77,24,0,0,0,TLX1;T-cell leukemia homeobox 1,GO:0005634//nucleus,GO:0008284//positive regulation of cell proliferation;GO:0030182//neuron differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0048645//organ formation;GO:0048536//spleen development;GO:0007417//central nervous system development,GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity,K09340//Transcriptional misregulation in cancer
3196,0,0,0,0,0,24,1,0,11,0,0,0,TLX2;T-cell leukemia homeobox 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0050774//negative regulation of dendrite morphogenesis;GO:0001707//mesoderm formation;GO:0006351//transcription, DNA-templated;GO:0048484//enteric nervous system development",GO:0043565//sequence-specific DNA binding,-
3198,0,0,0,0,0,3,0,0,40,0,0,0,HOXA1;homeobox A1,GO:0005634//nucleus,"GO:0060876//semicircular canal formation;GO:0007634//optokinetic behavior;GO:0021599//abducens nerve formation;GO:0007605//sensory perception of sound;GO:0021754//facial nucleus development;GO:0009653//anatomical structure morphogenesis;GO:0042473//outer ear morphogenesis;GO:0008045//motor neuron axon guidance;GO:0006351//transcription, DNA-templated;GO:0048702//embryonic neurocranium morphogenesis;GO:0021953//central nervous system neuron differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0048839//inner ear development;GO:0090103//cochlea morphogenesis;GO:0050795//regulation of behavior;GO:0048844//artery morphogenesis;GO:0050905//neuromuscular process;GO:0050890//cognition;GO:0021569//rhombomere 3 development;GO:0021570//rhombomere 4 development;GO:0007275//multicellular organismal development;GO:0060840//artery development;GO:0021571//rhombomere 5 development;GO:0021612//facial nerve structural organization;GO:0090102//cochlea development",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
3199,0,0,0,0,0,15,0,0,0,0,0,0,HOXA2;homeobox A2,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0035284//brain segmentation;GO:0021568//rhombomere 2 development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042474//middle ear morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0002076//osteoblast development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009953//dorsal/ventral pattern formation;GO:0008045//motor neuron axon guidance;GO:0006351//transcription, DNA-templated;GO:0048703//embryonic viscerocranium morphogenesis;GO:0007379//segment specification;GO:0001709//cell fate determination;GO:0021658//rhombomere 3 morphogenesis;GO:0045665//negative regulation of neuron differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
32,0,0,0,0,20,42,68,59,63,0,5,0,ACACB;acetyl-CoA carboxylase beta,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0012505//endomembrane system;GO:0005634//nucleus,GO:0006084//acetyl-CoA metabolic process;GO:0051289//protein homotetramerization;GO:0042493//response to drug;GO:0006633//fatty acid biosynthetic process;GO:0014070//response to organic cyclic compound;GO:0044255//cellular lipid metabolic process;GO:2001295//malonyl-CoA biosynthetic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006768//biotin metabolic process;GO:0031325//positive regulation of cellular metabolic process;GO:0006766//vitamin metabolic process;GO:0006112//energy reserve metabolic process;GO:0006853//carnitine shuttle,GO:0004075//biotin carboxylase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0009374//biotin binding;GO:0003989//acetyl-CoA carboxylase activity,K11262//Fatty acid biosynthesis;Adipocytokine signaling pathway;Pyruvate metabolism;Propanoate metabolism;Insulin signaling pathway;Metabolic pathways
320,1,0,0,0,9,19,0,0,15,32,0,447,"APBA1;amyloid beta (A4) precursor protein-binding, family A, member 1",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0008021//synaptic vesicle,GO:0010468//regulation of gene expression;GO:0035264//multicellular organism growth;GO:0014051//gamma-aminobutyric acid secretion;GO:0014047//glutamate secretion;GO:0008088//axon cargo transport;GO:0007155//cell adhesion;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0006461//protein complex assembly;GO:0007626//locomotory behavior;GO:0001701//in utero embryonic development;GO:0006886//intracellular protein transport,"GO:0001540//beta-amyloid binding;GO:0032403//protein complex binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0030165//PDZ domain binding;GO:0005515//protein binding",-
3200,0,10,18,8,6,0,0,0,0,0,0,0,HOXA3;homeobox A3,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3201,0,0,0,0,0,13,29,0,3,0,0,0,HOXA4;homeobox A4,GO:0005634//nucleus,"GO:0009952//anterior/posterior pattern specification;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
3202,0,0,0,0,0,0,0,0,0,0,5,0,HOXA5;homeobox A5,GO:0005634//nucleus,"GO:0060644//mammary gland epithelial cell differentiation;GO:0048286//lung alveolus development;GO:0003016//respiratory system process;GO:0045647//negative regulation of erythrocyte differentiation;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0060638//mesenchymal-epithelial cell signaling;GO:0060574//intestinal epithelial cell maturation;GO:0060484//lung-associated mesenchyme development;GO:0060535//trachea cartilage morphogenesis;GO:0060435//bronchiole development;GO:0035264//multicellular organism growth;GO:0006351//transcription, DNA-templated;GO:0060749//mammary gland alveolus development;GO:0010870//positive regulation of receptor biosynthetic process;GO:0060764//cell-cell signaling involved in mammary gland development;GO:0030878//thyroid gland development;GO:0016477//cell migration;GO:0060480//lung goblet cell differentiation;GO:0016525//negative regulation of angiogenesis;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0043065//positive regulation of apoptotic process;GO:0045639//positive regulation of myeloid cell differentiation;GO:0048704//embryonic skeletal system morphogenesis",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
3203,0,0,0,0,0,0,0,0,7,40,0,0,HOXA6;homeobox A6,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis;GO:0006351//transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3204,0,0,0,13,0,0,0,0,0,0,0,0,HOXA7;homeobox A7,GO:0005634//nucleus,"GO:0045656//negative regulation of monocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001525//angiogenesis;GO:0002686//negative regulation of leukocyte migration;GO:0048863//stem cell differentiation;GO:0045617//negative regulation of keratinocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048704//embryonic skeletal system morphogenesis",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding,-
3206,0,71,39,81,210,0,0,0,0,0,45,261,HOXA10;homeobox A10,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0007338//single fertilization;GO:0060065//uterus development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:0009952//anterior/posterior pattern specification;GO:0030326//embryonic limb morphogenesis;GO:0007275//multicellular organismal development;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated",GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K09296//Transcriptional misregulation in cancer;K09295//Transcriptional misregulation in cancer
3207,0,440,405,354,563,30,56,1064,242,1,970,2,HOXA11;homeobox A11,GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0032993//protein-DNA complex,"GO:0007338//single fertilization;GO:0007501//mesodermal cell fate specification;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0048589//developmental growth;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0010720//positive regulation of cell development;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0001501//skeletal system development;GO:0035115//embryonic forelimb morphogenesis;GO:0001656//metanephros development;GO:0032332//positive regulation of chondrocyte differentiation;GO:0001759//organ induction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060065//uterus development;GO:0030326//embryonic limb morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0060272//embryonic skeletal joint morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K09296//Transcriptional misregulation in cancer
3208,0,38,0,47,93,18,0,86,59,0,81,0,HPCA;hippocalcin,-,GO:0048839//inner ear development,GO:0003779//actin binding;GO:0005509//calcium ion binding,K13764//Phototransduction
3209,0,30,0,4,1,0,0,67,0,0,0,0,HOXA13;homeobox A13,GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003281//ventricular septum development;GO:0001886//endothelial cell morphogenesis;GO:0048844//artery morphogenesis;GO:0048839//inner ear development;GO:0035115//embryonic forelimb morphogenesis;GO:0045840//positive regulation of mitosis;GO:0001501//skeletal system development;GO:0001894//tissue homeostasis;GO:0030510//regulation of BMP signaling pathway;GO:0060442//branching involved in prostate gland morphogenesis;GO:0001570//vasculogenesis;GO:0030539//male genitalia development;GO:0006351//transcription, DNA-templated;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0060847//endothelial cell fate specification",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding,-
321,1,0,25,0,16,0,34,60,24,0,2,179,"APBA2;amyloid beta (A4) precursor protein-binding, family A, member 2",GO:0005886//plasma membrane,GO:0007399//nervous system development;GO:0015031//protein transport;GO:0007268//synaptic transmission;GO:0010468//regulation of gene expression;GO:0035264//multicellular organism growth;GO:0007626//locomotory behavior;GO:0001701//in utero embryonic development,GO:0005515//protein binding;GO:0001540//beta-amyloid binding,-
3211,0,0,0,0,0,0,3,0,0,31,0,0,HOXB1;homeobox B1,GO:0005634//nucleus,"GO:0048646//anatomical structure formation involved in morphogenesis;GO:0006351//transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organismal development;GO:0021570//rhombomere 4 development;GO:0021612//facial nerve structural organization;GO:0007389//pattern specification process;GO:0021571//rhombomere 5 development;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021754//facial nucleus development;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0019904//protein domain specific binding,-
3212,0,0,0,0,12,0,0,0,36,0,20,0,HOXB2;homeobox B2,GO:0005634//nucleus,"GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0008015//blood circulation;GO:0021569//rhombomere 3 development;GO:0009953//dorsal/ventral pattern formation;GO:0006351//transcription, DNA-templated;GO:0021612//facial nerve structural organization;GO:0007275//multicellular organismal development;GO:0048704//embryonic skeletal system morphogenesis;GO:0021570//rhombomere 4 development;GO:0002011//morphogenesis of an epithelial sheet",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3213,76,0,0,7,11,0,0,18,31,53,0,0,HOXB3;homeobox B3,GO:0005634//nucleus,"GO:0001525//angiogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0051216//cartilage development;GO:0021546//rhombomere development;GO:0030878//thyroid gland development;GO:0009952//anterior/posterior pattern specification;GO:0060216//definitive hemopoiesis;GO:0060324//face development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048704//embryonic skeletal system morphogenesis;GO:0021615//glossopharyngeal nerve morphogenesis;GO:0050767//regulation of neurogenesis;GO:0006351//transcription, DNA-templated",GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3215,39,0,0,0,0,0,0,0,0,0,0,0,HOXB5;homeobox B5,GO:0005634//nucleus,"GO:0048704//embryonic skeletal system morphogenesis;GO:0045446//endothelial cell differentiation;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
3216,0,0,0,0,0,0,0,0,10,0,0,0,HOXB6;homeobox B6,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0034101//erythrocyte homeostasis;GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0043565//sequence-specific DNA binding,K09294//Transcriptional misregulation in cancer
3217,0,0,0,0,0,7,0,1,9,0,0,549,HOXB7;homeobox B7,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0030099//myeloid cell differentiation;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3218,0,0,0,0,0,0,0,0,22,0,0,0,HOXB8;homeobox B8,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0019233//sensory perception of pain;GO:0045638//negative regulation of myeloid cell differentiation;GO:0008344//adult locomotory behavior;GO:0007625//grooming behavior;GO:0048704//embryonic skeletal system morphogenesis;GO:0021516//dorsal spinal cord development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3219,0,0,0,0,0,0,0,60,24,0,0,0,HOXB9;homeobox B9,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0009952//anterior/posterior pattern specification;GO:0048706//embryonic skeletal system development;GO:0060070//canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030879//mammary gland development;GO:0060326//cell chemotaxis",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,K09294//Transcriptional misregulation in cancer
322,0,1,0,0,32,19,22,38,13,0,0,0,"APBB1;amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)",GO:0045202//synapse;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0030027//lamellipodium,"GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0043065//positive regulation of apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043967//histone H4 acetylation;GO:0050760//negative regulation of thymidylate synthase biosynthetic process;GO:0007165//signal transduction;GO:0007050//cell cycle arrest;GO:0006355//regulation of transcription, DNA-templated;GO:0007409//axonogenesis",GO:0003682//chromatin binding;GO:0001540//beta-amyloid binding;GO:0008134//transcription factor binding;GO:0042393//histone binding;GO:0005515//protein binding;GO:0070064//proline-rich region binding,K04529//Alzheimer's disease
3221,0,0,0,0,0,0,0,0,30,0,0,0,HOXC4;homeobox C4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
3223,0,0,0,0,20,0,46,0,0,0,0,0,HOXC6;homeobox C6,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0048706//embryonic skeletal system development",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
3224,0,0,0,0,0,0,0,0,2,0,0,0,HOXC8;homeobox C8,GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048705//skeletal system morphogenesis;GO:0030182//neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
3225,0,0,0,0,0,19,0,0,26,0,0,0,HOXC9;homeobox C9,GO:0005634//nucleus,"GO:0009952//anterior/posterior pattern specification;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis",GO:0043565//sequence-specific DNA binding,K09294//Transcriptional misregulation in cancer
3226,0,0,0,0,0,0,31,0,9,0,0,0,HOXC10;homeobox C10,GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0009954//proximal/distal pattern formation;GO:0009952//anterior/posterior pattern specification;GO:0021520//spinal cord motor neuron cell fate specification;GO:0030326//embryonic limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0050905//neuromuscular process;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K09295//Transcriptional misregulation in cancer
3227,0,0,0,0,0,16,0,0,0,0,0,1,HOXC11;homeobox C11,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0060272//embryonic skeletal joint morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0007492//endoderm development;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0001656//metanephros development;GO:0001759//organ induction",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K09296//Transcriptional misregulation in cancer
3228,0,0,0,0,0,0,0,0,28,0,0,0,HOXC12;homeobox C12,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
3229,0,0,0,0,0,0,0,0,16,0,0,0,HOXC13;homeobox C13,GO:0005634//nucleus,"GO:0001942//hair follicle development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0043587//tongue morphogenesis;GO:0035878//nail development",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
323,22,18,39,66,76,50,16,66,73,0,35,0,"APBB2;amyloid beta (A4) precursor protein-binding, family B, member 2",GO:0016020//membrane;GO:0045202//synapse;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0030198//extracellular matrix organization;GO:0006355//regulation of transcription, DNA-templated;GO:0007050//cell cycle arrest;GO:0001764//neuron migration;GO:0043065//positive regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0030308//negative regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0007411//axon guidance",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0001540//beta-amyloid binding,-
3231,0,1,10,0,10,15,0,2,10,0,19,0,HOXD1;homeobox D1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0019233//sensory perception of pain;GO:0048706//embryonic skeletal system development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
3232,0,0,0,0,0,27,10,0,23,0,13,0,HOXD3;homeobox D3,GO:0005634//nucleus,"GO:0007160//cell-matrix adhesion;GO:0006351//transcription, DNA-templated;GO:0010628//positive regulation of gene expression;GO:0048704//embryonic skeletal system morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0030878//thyroid gland development;GO:0051216//cartilage development;GO:0045666//positive regulation of neuron differentiation;GO:0007219//Notch signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3233,111,0,0,0,0,0,0,56,4,0,0,0,HOXD4;homeobox D4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3234,0,0,41,0,23,0,0,0,0,0,3,0,HOXD8;homeobox D8,GO:0005634//nucleus,"GO:0008595//anterior/posterior axis specification, embryo;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048705//skeletal system morphogenesis",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3235,0,0,0,0,0,0,0,44,0,152,0,0,HOXD9;homeobox D9,GO:0005634//nucleus,"GO:0008344//adult locomotory behavior;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007338//single fertilization;GO:0035115//embryonic forelimb morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0048935//peripheral nervous system neuron development;GO:0035137//hindlimb morphogenesis;GO:0006351//transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis;GO:0030879//mammary gland development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,K09294//Transcriptional misregulation in cancer
3236,0,1,67,5,22,0,0,0,25,0,2,0,HOXD10;homeobox D10,GO:0005634//nucleus,"GO:0008344//adult locomotory behavior;GO:0030326//embryonic limb morphogenesis;GO:0009952//anterior/posterior pattern specification;GO:0021520//spinal cord motor neuron cell fate specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009954//proximal/distal pattern formation;GO:0007338//single fertilization;GO:0007519//skeletal muscle tissue development;GO:0035137//hindlimb morphogenesis;GO:0048935//peripheral nervous system neuron development;GO:0035136//forelimb morphogenesis;GO:0050905//neuromuscular process;GO:0006351//transcription, DNA-templated;GO:0048704//embryonic skeletal system morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding,K09295//Transcriptional misregulation in cancer
3237,0,0,0,0,1,0,0,0,0,0,0,0,HOXD11;homeobox D11,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0001759//organ induction;GO:0032332//positive regulation of chondrocyte differentiation;GO:0001656//metanephros development;GO:0009953//dorsal/ventral pattern formation;GO:0060272//embryonic skeletal joint morphogenesis;GO:0006351//transcription, DNA-templated;GO:0042733//embryonic digit morphogenesis;GO:0010720//positive regulation of cell development;GO:0009954//proximal/distal pattern formation;GO:0009952//anterior/posterior pattern specification;GO:0048589//developmental growth;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0007338//single fertilization;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0035115//embryonic forelimb morphogenesis",GO:0043565//sequence-specific DNA binding,K09296//Transcriptional misregulation in cancer
3238,0,0,0,0,0,0,0,0,6,0,0,0,HOXD12;homeobox D12,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0042733//embryonic digit morphogenesis;GO:0007389//pattern specification process;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
3239,31,0,0,0,11,32,14,0,0,94,9,0,HOXD13;homeobox D13,GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0060571//morphogenesis of an epithelial fold;GO:0001501//skeletal system development;GO:0048619//embryonic hindgut morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0007275//multicellular organismal development;GO:0042127//regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060602//branch elongation of an epithelium;GO:0009952//anterior/posterior pattern specification;GO:0006355//regulation of transcription, DNA-templated;GO:0030539//male genitalia development;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
324,78,0,2,19,20,0,42,0,53,0,12,0,APC;adenomatous polyposis coli,GO:0005923//tight junction;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005634//nucleus;GO:0035371//microtubule plus-end;GO:0030877//beta-catenin destruction complex;GO:0005886//plasma membrane;GO:0000776//kinetochore;GO:0005881//cytoplasmic microtubule;GO:0044295//axonal growth cone;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0030027//lamellipodium;GO:0016328//lateral plasma membrane;GO:0005913//cell-cell adherens junction,GO:0048538//thymus development;GO:0000281//mitotic cytokinesis;GO:0045732//positive regulation of protein catabolic process;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0007409//axonogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0030335//positive regulation of cell migration;GO:0032886//regulation of microtubule-based process;GO:0031122//cytoplasmic microtubule organization;GO:0006974//cellular response to DNA damage stimulus;GO:0051171//regulation of nitrogen compound metabolic process;GO:0045785//positive regulation of cell adhesion;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0070830//tight junction assembly;GO:0006915//apoptotic process;GO:0046716//muscle cell cellular homeostasis;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0009798//axis specification;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0031274//positive regulation of pseudopodium assembly;GO:0045667//regulation of osteoblast differentiation;GO:0007026//negative regulation of microtubule depolymerization;GO:0043065//positive regulation of apoptotic process;GO:0045670//regulation of osteoclast differentiation;GO:0031116//positive regulation of microtubule polymerization;GO:0044337//canonical Wnt signaling pathway involved in positive regulation of apoptotic process;GO:0006461//protein complex assembly;GO:0001942//hair follicle development;GO:0001822//kidney development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0016477//cell migration;GO:0043409//negative regulation of MAPK cascade;GO:0060041//retina development in camera-type eye;GO:0051781//positive regulation of cell division;GO:0035019//somatic stem cell maintenance;GO:0007050//cell cycle arrest;GO:0007094//mitotic spindle assembly checkpoint;GO:0042483//negative regulation of odontogenesis;GO:0051276//chromosome organization;GO:0033077//T cell differentiation in thymus;GO:0007155//cell adhesion,GO:0051010//microtubule plus-end binding;GO:0008013//beta-catenin binding;GO:0045295//gamma-catenin binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0045296//cadherin binding;GO:0019887//protein kinase regulator activity;GO:0005515//protein binding,K02085//Colorectal cancer;Basal cell carcinoma;HTLV-I infection;Regulation of actin cytoskeleton;Wnt signaling pathway;Endometrial cancer;Pathways in cancer
3241,0,1,0,6,0,36,0,30,35,0,0,0,HPCAL1;hippocalcin-like 1,GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction,GO:0005509//calcium ion binding,K13764//Phototransduction
3242,93,0,0,4,32,0,28,87,9,0,51,0,HPD;4-hydroxyphenylpyruvate dioxygenase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006559//L-phenylalanine catabolic process;GO:0055114//oxidation-reduction process;GO:0006572//tyrosine catabolic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity;GO:0046872//metal ion binding,K00457//Ubiquinone and other terpenoid-quinone biosynthesis;Phenylalanine metabolism;Tyrosine metabolism;Metabolic pathways
3248,0,0,0,1,18,26,0,0,67,0,0,0,HPGD;hydroxyprostaglandin dehydrogenase 15-(NAD),GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007567//parturition;GO:0019371//cyclooxygenase pathway;GO:0070493//thrombin receptor signaling pathway;GO:0097070//ductus arteriosus closure;GO:0006693//prostaglandin metabolic process;GO:0045786//negative regulation of cell cycle;GO:0007565//female pregnancy;GO:2001300//lipoxin metabolic process;GO:0019372//lipoxygenase pathway;GO:0055114//oxidation-reduction process;GO:0030728//ovulation;GO:0019369//arachidonic acid metabolic process,GO:0070403//NAD+ binding;GO:0051287//NAD binding;GO:0042803//protein homodimerization activity;GO:0016404//15-hydroxyprostaglandin dehydrogenase (NAD+) activity;GO:0003824//catalytic activity;GO:0004957//prostaglandin E receptor activity,K00069//Transcriptional misregulation in cancer
3249,0,0,0,0,0,15,0,1,4,0,31,0,HPN;hepsin,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0043025//neuronal cell body;GO:0005911//cell-cell junction;GO:0031965//nuclear membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0010756//positive regulation of plasminogen activation;GO:0097066//response to thyroid hormone;GO:0050680//negative regulation of epithelial cell proliferation;GO:0090103//cochlea morphogenesis;GO:0042632//cholesterol homeostasis;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0043923//positive regulation by host of viral transcription;GO:2000611//positive regulation of thyroid hormone generation;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060429//epithelium development;GO:0006508//proteolysis;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:2000347//positive regulation of hepatocyte proliferation;GO:0034769//basement membrane disassembly;GO:0097195//pilomotor reflex;GO:0030307//positive regulation of cell growth;GO:0008360//regulation of cell shape;GO:0071805//potassium ion transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression,GO:0008236//serine-type peptidase activity;GO:0008233//peptidase activity;GO:0015269//calcium-activated potassium channel activity;GO:0004252//serine-type endopeptidase activity;GO:0070008//serine-type exopeptidase activity;GO:0005515//protein binding,-
325,0,0,0,0,0,0,51,0,0,0,0,0,"APCS;amyloid P component, serum",GO:0043234//protein complex;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0046597//negative regulation of viral entry into host cell;GO:0061045//negative regulation of wound healing;GO:1903016//negative regulation of exo-alpha-sialidase activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0006953//acute-phase response;GO:0002674//negative regulation of acute inflammatory response;GO:0006457//protein folding;GO:0045087//innate immune response;GO:0045656//negative regulation of monocyte differentiation;GO:1903019//negative regulation of glycoprotein metabolic process;GO:0048525//negative regulation of viral process,GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding;GO:0030246//carbohydrate binding;GO:0001849//complement component C1q binding;GO:0046790//virion binding,K01672//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Nitrogen metabolism;Pancreatic secretion;Collecting duct acid secretion
3250,0,0,0,0,0,13,0,0,0,0,0,0,HPR;haptoglobin-related protein,GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0034366//spherical high-density lipoprotein particle,GO:0008152//metabolic process,GO:0030492//hemoglobin binding;GO:0003824//catalytic activity,K01330//Complement and coagulation cascades;Pertussis;Staphylococcus aureus infection;Phagosome;Systemic lupus erythematosus;K14477//African trypanosomiasis
3251,0,25,0,30,151,0,0,0,0,0,3,0,HPRT1;hypoxanthine phosphoribosyltransferase 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0046100//hypoxanthine metabolic process;GO:0006168//adenine salvage;GO:0006166//purine ribonucleoside salvage;GO:0001975//response to amphetamine;GO:0046651//lymphocyte proliferation;GO:0006178//guanine salvage;GO:0007625//grooming behavior;GO:0021954//central nervous system neuron development;GO:0006144//purine nucleobase metabolic process;GO:0021756//striatum development;GO:0044281//small molecule metabolic process;GO:0032263//GMP salvage;GO:0043103//hypoxanthine salvage;GO:0043101//purine-containing compound salvage;GO:0006164//purine nucleotide biosynthetic process;GO:0051289//protein homotetramerization;GO:0045964//positive regulation of dopamine metabolic process;GO:0007626//locomotory behavior;GO:0032264//IMP salvage;GO:0021895//cerebral cortex neuron differentiation;GO:0048813//dendrite morphogenesis;GO:0046038//GMP catabolic process;GO:0042417//dopamine metabolic process;GO:0019835//cytolysis;GO:0046040//IMP metabolic process,GO:0004422//hypoxanthine phosphoribosyltransferase activity;GO:0052657//guanine phosphoribosyltransferase activity;GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity;GO:0000166//nucleotide binding;GO:0005515//protein binding,K00760//Metabolic pathways;Biosynthesis of secondary metabolites;Drug metabolism - other enzymes;Selenocompound metabolism;Purine metabolism
3257,50,29,1,9,28,12,4,96,30,0,7,0,HPS1;Hermansky-Pudlak syndrome 1,GO:0005887//integral component of plasma membrane;GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031085//BLOC-3 complex,GO:0032816//positive regulation of natural killer cell activation;GO:0007040//lysosome organization;GO:0007596//blood coagulation;GO:0033299//secretion of lysosomal enzymes;GO:0048069//eye pigmentation;GO:0060041//retina development in camera-type eye;GO:0007601//visual perception;GO:0030318//melanocyte differentiation,GO:0005515//protein binding;GO:0046983//protein dimerization activity,-
326,0,0,1,0,1,0,0,0,23,0,16,0,AIRE;autoimmune regulator,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006417//regulation of translation;GO:0006355//regulation of transcription, DNA-templated;GO:0006955//immune response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006959//humoral immune response",GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0045182//translation regulator activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042393//histone binding;GO:0008270//zinc ion binding,K10603//Ubiquitin mediated proteolysis;Primary immunodeficiency
3263,0,0,0,0,0,10,0,0,9,0,3,0,HPX;hemopexin,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0005615//extracellular space;GO:0071682//endocytic vesicle lumen,GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0016032//viral process;GO:0015886//heme transport;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0006879//cellular iron ion homeostasis;GO:0042168//heme metabolic process;GO:0020027//hemoglobin metabolic process;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0002639//positive regulation of immunoglobulin production,GO:0015232//heme transporter activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K01394//Rheumatoid arthritis;Transcriptional misregulation in cancer
326340,84,0,0,8,0,24,19,0,11,0,9,0,ZAR1;zygote arrest 1,GO:0005737//cytoplasm,GO:0007275//multicellular organismal development,-,-
326342,0,0,0,0,0,0,49,0,33,0,17,0,"EMR4P;egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene",-,-,-,-
3265,0,13,0,4,22,0,0,49,49,95,29,110,HRAS;Harvey rat sarcoma viral oncogene homolog,GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0043524//negative regulation of neuron apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0008542//visual learning;GO:0007050//cell cycle arrest;GO:0007596//blood coagulation;GO:0006935//chemotaxis;GO:0035176//social behavior;GO:0034259//negative regulation of Rho GTPase activity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007166//cell surface receptor signaling pathway;GO:0006897//endocytosis;GO:0001934//positive regulation of protein phosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0007093//mitotic cell cycle checkpoint;GO:0045087//innate immune response;GO:1900029//positive regulation of ruffle assembly;GO:0010629//negative regulation of gene expression;GO:0043410//positive regulation of MAPK cascade;GO:0007264//small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0009887//organ morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0046330//positive regulation of JNK cascade;GO:2000630//positive regulation of miRNA metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0045596//negative regulation of cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045740//positive regulation of DNA replication;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0007268//synaptic transmission;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0090398//cellular senescence;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0035022//positive regulation of Rac protein signal transduction;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0032855//positive regulation of Rac GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process;GO:0000165//MAPK cascade;GO:0090303//positive regulation of wound healing;GO:0097193//intrinsic apoptotic signaling pathway;GO:0030335//positive regulation of cell migration;GO:0007411//axon guidance",GO:0005515//protein binding;GO:0005525//GTP binding;GO:0008022//protein C-terminus binding,K02833//Tight junction;Fc epsilon RI signaling pathway;Acute myeloid leukemia;Cholinergic synapse;B cell receptor signaling pathway;Non-small cell lung cancer;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Hepatitis C;Melanoma;Melanogenesis;Axon guidance;Endocytosis;Insulin signaling pathway;Prostate cancer;Long-term potentiation;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Chronic myeloid leukemia;HTLV-I infection;Long-term depression;Endometrial cancer;Glioma;Focal adhesion;VEGF signaling pathway;Thyroid cancer;Gap junction;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Alcoholism;Serotonergic synapse;MAPK signaling pathway;ErbB signaling pathway;Bladder cancer;Renal cell carcinoma
326624,124,0,0,0,0,19,16,0,37,0,0,1,"RAB37;RAB37, member RAS oncogene family",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0030141//secretory granule,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005525//GTP binding,-
326625,0,27,1,23,180,25,1,0,5,0,0,0,MMAB;methylmalonic aciduria (cobalamin deficiency) cblB type,GO:0005759//mitochondrial matrix,GO:0009235//cobalamin metabolic process;GO:0006766//vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0009236//cobalamin biosynthetic process,"GO:0008817//cob(I)yrinic acid a,c-diamide adenosyltransferase activity;GO:0005524//ATP binding",K00798//Metabolic pathways;Porphyrin and chlorophyll metabolism
3267,0,28,0,21,79,0,124,0,57,14,0,0,AGFG1;ArfGAP with FG repeats 1,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0005643//nuclear pore,GO:0030154//cell differentiation;GO:0006406//mRNA export from nucleus;GO:0043547//positive regulation of GTPase activity;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0032312//regulation of ARF GTPase activity,GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003723//RNA binding,K15044//Influenza A
3268,0,0,0,1,4,18,59,0,59,0,12,0,AGFG2;ArfGAP with FG repeats 2,GO:0016020//membrane,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity,GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K15044//Influenza A
3269,0,0,0,0,0,14,7,0,16,0,0,0,HRH1;histamine receptor H1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0008542//visual learning;GO:0006954//inflammatory response;GO:0048245//eosinophil chemotaxis;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0007613//memory;GO:0048016//inositol phosphate-mediated signaling;GO:0071420//cellular response to histamine;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0043114//regulation of vascular permeability;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045907//positive regulation of vasoconstriction,GO:0004930//G-protein coupled receptor activity;GO:0004969//histamine receptor activity,K04149//Neuroactive ligand-receptor interaction;Calcium signaling pathway
327,0,3,0,13,38,0,0,0,21,81,28,760,APEH;acylaminoacyl-peptide hydrolase,GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0050435//beta-amyloid metabolic process,GO:0044822//poly(A) RNA binding;GO:0004252//serine-type endopeptidase activity;GO:0008242//omega peptidase activity,-
3270,0,0,0,0,0,0,0,0,28,0,0,0,HRC;histidine rich calcium binding protein,GO:0030018//Z disc;GO:0033018//sarcoplasmic reticulum lumen;GO:0033017//sarcoplasmic reticulum membrane,GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0010460//positive regulation of heart rate;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0006936//muscle contraction;GO:0051480//cytosolic calcium ion homeostasis;GO:0045823//positive regulation of heart contraction;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0002027//regulation of heart rate,GO:0051117//ATPase binding;GO:0005509//calcium ion binding;GO:0044325//ion channel binding;GO:0005515//protein binding,-
3273,0,0,0,0,0,0,0,0,15,0,0,298,HRG;histidine-rich glycoprotein,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0031093//platelet alpha granule lumen,GO:2000504//positive regulation of blood vessel remodeling;GO:0001525//angiogenesis;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0030193//regulation of blood coagulation;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0032956//regulation of actin cytoskeleton organization;GO:0030308//negative regulation of cell growth;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0050832//defense response to fungus;GO:0042730//fibrinolysis;GO:0051894//positive regulation of focal adhesion assembly;GO:0097037//heme export;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0010593//negative regulation of lamellipodium assembly;GO:0016525//negative regulation of angiogenesis;GO:0014070//response to organic cyclic compound;GO:0002576//platelet degranulation;GO:0043065//positive regulation of apoptotic process;GO:0002839//positive regulation of immune response to tumor cell;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0010543//regulation of platelet activation;GO:0007162//negative regulation of cell adhesion;GO:0010951//negative regulation of endopeptidase activity;GO:0043254//regulation of protein complex assembly;GO:0007596//blood coagulation;GO:0010468//regulation of gene expression;GO:0006935//chemotaxis,GO:0020037//heme binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0043395//heparan sulfate proteoglycan binding;GO:0005102//receptor binding;GO:0019865//immunoglobulin binding;GO:0008270//zinc ion binding;GO:0008201//heparin binding;GO:0046872//metal ion binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding,-
3274,0,0,0,0,7,0,34,0,30,0,17,0,HRH2;histamine receptor H2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007613//memory;GO:0048732//gland development;GO:0048565//digestive tract development;GO:0008542//visual learning;GO:0045907//positive regulation of vasoconstriction;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0001698//gastrin-induced gastric acid secretion;GO:0001697//histamine-induced gastric acid secretion;GO:0006955//immune response;GO:0048167//regulation of synaptic plasticity;GO:0003382//epithelial cell morphogenesis",GO:0004969//histamine receptor activity,K04150//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Gastric acid secretion
3275,0,1,1,0,57,0,65,82,45,1,13,0,PRMT2;protein arginine methyltransferase 2,GO:0035189//Rb-E2F complex;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006479//protein methylation;GO:0043065//positive regulation of apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0048588//developmental cell growth;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0034969//histone arginine methylation;GO:0060765//regulation of androgen receptor signaling pathway;GO:0007165//signal transduction;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016571//histone methylation",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042054//histone methyltransferase activity;GO:0042974//retinoic acid receptor binding;GO:0050681//androgen receptor binding;GO:0016274//protein-arginine N-methyltransferase activity;GO:0030331//estrogen receptor binding;GO:0004871//signal transducer activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0042975//peroxisome proliferator activated receptor binding;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0046966//thyroid hormone receptor binding;GO:0033142//progesterone receptor binding;GO:0003713//transcription coactivator activity,-
3276,0,0,0,6,13,0,0,0,17,0,0,0,PRMT1;protein arginine methyltransferase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0006479//protein methylation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0043985//histone H4-R3 methylation;GO:0007166//cell surface receptor signaling pathway;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0031175//neuron projection development;GO:0006355//regulation of transcription, DNA-templated;GO:0016571//histone methylation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042054//histone methyltransferase activity;GO:0008168//methyltransferase activity;GO:0042802//identical protein binding;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0008170//N-methyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity,-
327657,0,0,0,0,0,0,0,0,1,0,0,0,"SERPINA9;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9",GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016020//membrane,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03984//Complement and coagulation cascades;K03913//Complement and coagulation cascades
328,0,22,1,0,31,0,0,0,0,0,0,0,APEX1;APEX nuclease (multifunctional DNA repair enzyme) 1,GO:0005783//endoplasmic reticulum;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005840//ribosome;GO:0005739//mitochondrion;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005667//transcription factor complex,"GO:0045454//cell redox homeostasis;GO:0000737//DNA catabolic process, endonucleolytic;GO:0055114//oxidation-reduction process;GO:0043488//regulation of mRNA stability;GO:0071320//cellular response to cAMP;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006281//DNA repair;GO:0080111//DNA demethylation;GO:0006310//DNA recombination;GO:0007568//aging;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006284//base-excision repair;GO:0071375//cellular response to peptide hormone stimulus;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0014912//negative regulation of smooth muscle cell migration;GO:0070301//cellular response to hydrogen peroxide;GO:0045739//positive regulation of DNA repair;GO:0006351//transcription, DNA-templated;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006355//regulation of transcription, DNA-templated;GO:0042493//response to drug","GO:0046872//metal ion binding;GO:0004519//endonuclease activity;GO:0008311//double-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0016491//oxidoreductase activity;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0032403//protein complex binding;GO:0016890//site-specific endodeoxyribonuclease activity, specific for altered base;GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0003713//transcription coactivator activity;GO:0031490//chromatin DNA binding;GO:0003684//damaged DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004528//phosphodiesterase I activity;GO:0003714//transcription corepressor activity;GO:0051059//NF-kappaB binding;GO:0004520//endodeoxyribonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0008081//phosphoric diester hydrolase activity;GO:0004844//uracil DNA N-glycosylase activity;GO:0003677//DNA binding",K10771//Base excision repair
3280,0,0,0,7,0,0,0,0,0,0,0,0,HES1;hes family bHLH transcription factor 1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0061626//pharyngeal arch artery morphogenesis;GO:0048538//thymus development;GO:0035910//ascending aorta morphogenesis;GO:0060253//negative regulation of glial cell proliferation;GO:0003143//embryonic heart tube morphogenesis;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0021984//adenohypophysis development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021558//trochlear nerve development;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0046427//positive regulation of JAK-STAT cascade;GO:0060164//regulation of timing of neuron differentiation;GO:0003281//ventricular septum development;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030901//midbrain development;GO:0007219//Notch signaling pathway;GO:0021575//hindbrain morphogenesis;GO:0007262//STAT protein import into nucleus;GO:0006366//transcription from RNA polymerase II promoter;GO:0030324//lung development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0072012//glomerulus vasculature development;GO:0090102//cochlea development;GO:0045747//positive regulation of Notch signaling pathway;GO:0048711//positive regulation of astrocyte differentiation;GO:0007399//nervous system development;GO:0008284//positive regulation of cell proliferation;GO:0060675//ureteric bud morphogenesis;GO:0006461//protein complex assembly;GO:0048469//cell maturation;GO:2000737//negative regulation of stem cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0001889//liver development;GO:0042668//auditory receptor cell fate determination;GO:0060716//labyrinthine layer blood vessel development;GO:0045977//positive regulation of mitotic cell cycle, embryonic;GO:0043388//positive regulation of DNA binding;GO:0097150//neuronal stem cell maintenance;GO:0061009//common bile duct development;GO:0045598//regulation of fat cell differentiation;GO:0007224//smoothened signaling pathway;GO:0045608//negative regulation of auditory receptor cell differentiation;GO:0016477//cell migration;GO:0031018//endocrine pancreas development;GO:2000978//negative regulation of forebrain neuron differentiation;GO:0021861//forebrain radial glial cell differentiation;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0060412//ventricular septum morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0072282//metanephric nephron tubule morphogenesis;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0003151//outflow tract morphogenesis;GO:0048844//artery morphogenesis;GO:0097084//vascular smooth muscle cell development;GO:2000974//negative regulation of pro-B cell differentiation;GO:0021557//oculomotor nerve development;GO:0035019//somatic stem cell maintenance;GO:0021537//telencephalon development;GO:0007155//cell adhesion",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0008134//transcription factor binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0071820//N-box binding;GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0003677//DNA binding,K06054//Fanconi anemia pathway;Notch signaling pathway;Maturity onset diabetes of the young
3281,0,208,0,18,100,0,12,0,8,0,0,0,HSBP1;heat shock factor binding protein 1,GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:0006936//muscle contraction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0003714//transcription corepressor activity,-
3283,0,0,0,0,0,0,22,0,0,0,4,0,"HSD3B1;hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1",GO:0016021//integral component of membrane;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0030868//smooth endoplasmic reticulum membrane,GO:0006702//androgen biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0006705//mineralocorticoid biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process,GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0004769//steroid delta-isomerase activity,K00070//Steroid hormone biosynthesis;Metabolic pathways
3284,0,0,0,0,0,0,0,31,23,0,0,0,"HSD3B2;hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2",GO:0005789//endoplasmic reticulum membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane,GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0006705//mineralocorticoid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0006704//glucocorticoid biosynthetic process;GO:0006702//androgen biosynthetic process,GO:0004769//steroid delta-isomerase activity;GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity,K00070//Metabolic pathways;Steroid hormone biosynthesis
329,0,2,0,11,64,0,5,0,38,0,0,0,BIRC2;baculoviral IAP repeat containing 2,GO:0005634//nucleus;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0005829//cytosol,"GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0042127//regulation of cell proliferation;GO:0042981//regulation of apoptotic process;GO:0045088//regulation of innate immune response;GO:0060544//regulation of necroptotic process;GO:0034121//regulation of toll-like receptor signaling pathway;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045595//regulation of cell differentiation;GO:1902523//positive regulation of protein K63-linked ubiquitination;GO:0038061//NIK/NF-kappaB signaling;GO:0045087//innate immune response;GO:1902524//positive regulation of protein K48-linked ubiquitination;GO:1902527//positive regulation of protein monoubiquitination;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0039535//regulation of RIG-I signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0050727//regulation of inflammatory response;GO:0002224//toll-like receptor signaling pathway;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway",GO:0003713//transcription coactivator activity;GO:0047485//protein N-terminus binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,K16060//Focal adhesion;Apoptosis;Toxoplasmosis;Transcriptional misregulation in cancer;Ubiquitin mediated proteolysis;Small cell lung cancer;NOD-like receptor signaling pathway;Pathways in cancer;NF-kappa B signaling pathway
3290,0,0,0,0,0,17,0,0,38,0,0,0,HSD11B1;hydroxysteroid (11-beta) dehydrogenase 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0008202//steroid metabolic process;GO:0030324//lung development;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0006704//glucocorticoid biosynthetic process,GO:0070524//11-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0003845//11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity,K15680//Metabolic pathways;Steroid hormone biosynthesis;Metabolism of xenobiotics by cytochrome P450
3291,0,0,0,0,0,0,0,0,72,0,0,7,HSD11B2;hydroxysteroid (11-beta) dehydrogenase 2,GO:0005783//endoplasmic reticulum,GO:0051384//response to glucocorticoid;GO:0002017//regulation of blood volume by renal aldosterone;GO:0006704//glucocorticoid biosynthetic process;GO:0032868//response to insulin;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0055114//oxidation-reduction process;GO:0032094//response to food;GO:0001666//response to hypoxia,GO:0003845//11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity;GO:0051287//NAD binding;GO:0005496//steroid binding,K00071//Aldosterone-regulated sodium reabsorption;Steroid hormone biosynthesis
3292,0,316,257,334,447,0,20,1125,258,1,964,0,HSD17B1;hydroxysteroid (17-beta) dehydrogenase 1,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane,GO:0060348//bone development;GO:0008202//steroid metabolic process;GO:0061370//testosterone biosynthetic process;GO:0071248//cellular response to metal ion;GO:0008210//estrogen metabolic process;GO:0055114//oxidation-reduction process;GO:0006694//steroid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006703//estrogen biosynthetic process,GO:0003824//catalytic activity;GO:0004303//estradiol 17-beta-dehydrogenase activity,K00044//Biosynthesis of unsaturated fatty acids;Steroid hormone biosynthesis;Metabolic pathways;Fatty acid elongation
3293,0,0,0,0,0,0,21,0,0,0,0,0,HSD17B3;hydroxysteroid (17-beta) dehydrogenase 3,GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0030539//male genitalia development;GO:0006702//androgen biosynthetic process;GO:0061370//testosterone biosynthetic process;GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process,GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity,K10207//Metabolic pathways;Steroid hormone biosynthesis
3294,0,0,0,0,0,0,0,0,5,23,0,0,HSD17B2;hydroxysteroid (17-beta) dehydrogenase 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0032526//response to retinoic acid;GO:0001701//in utero embryonic development;GO:0055114//oxidation-reduction process;GO:0001890//placenta development;GO:0006694//steroid biosynthetic process,"GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0047006//17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity",K13368//Metabolic pathways;Steroid hormone biosynthesis
3295,64,118,2,182,668,2,0,0,9,0,27,0,HSD17B4;hydroxysteroid (17-beta) dehydrogenase 4,GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome,GO:0001649//osteoblast differentiation;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0036111//very long-chain fatty-acyl-CoA metabolic process;GO:0036112//medium-chain fatty-acyl-CoA metabolic process;GO:0055114//oxidation-reduction process;GO:0008210//estrogen metabolic process;GO:0008209//androgen metabolic process;GO:0006699//bile acid biosynthetic process;GO:0060009//Sertoli cell development;GO:0044255//cellular lipid metabolic process;GO:0000038//very long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0036109//alpha-linolenic acid metabolic process;GO:0008152//metabolic process;GO:0008206//bile acid metabolic process,"GO:0033989//3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity;GO:0042803//protein homodimerization activity;GO:0016508//long-chain-enoyl-CoA hydratase activity;GO:0044594//17-beta-hydroxysteroid dehydrogenase (NAD+) activity;GO:0016853//isomerase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0005102//receptor binding",K12405//Metabolic pathways;Primary bile acid biosynthesis;Peroxisome
3297,26,0,0,0,0,0,0,33,31,0,0,0,HSF1;heat shock transcription factor 1,GO:0005730//nucleolus;GO:0045120//pronucleus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex,"GO:0007283//spermatogenesis;GO:0007143//female meiotic division;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0006468//protein phosphorylation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032496//response to lipopolysaccharide;GO:0006351//transcription, DNA-templated;GO:0060136//embryonic process involved in female pregnancy;GO:0090231//regulation of spindle checkpoint;GO:0001892//embryonic placenta development;GO:0006952//defense response;GO:0040018//positive regulation of multicellular organism growth;GO:0034605//cellular response to heat;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09414//Legionellosis
3298,0,0,0,12,11,11,0,104,37,1,0,0,HSF2;heat shock transcription factor 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006950//response to stress;GO:0007283//spermatogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003713//transcription coactivator activity;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
3299,0,0,0,0,0,13,0,0,0,0,0,0,HSF4;heat shock transcription factor 4,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0008284//positive regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048468//cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0043010//camera-type eye development;GO:0033169//histone H3-K9 demethylation;GO:0070207//protein homotrimerization;GO:0045597//positive regulation of cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006950//response to stress;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019903//protein phosphatase binding;GO:0003714//transcription corepressor activity,-
33,0,0,20,48,58,5,0,0,34,0,27,0,"ACADL;acyl-CoA dehydrogenase, long chain",GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane,"GO:0090181//regulation of cholesterol metabolic process;GO:0055114//oxidation-reduction process;GO:0042758//long-chain fatty acid catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0001659//temperature homeostasis;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0044242//cellular lipid catabolic process;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0051289//protein homotetramerization;GO:0019254//carnitine metabolic process, CoA-linked;GO:0044255//cellular lipid metabolic process;GO:0046322//negative regulation of fatty acid oxidation;GO:0042413//carnitine catabolic process;GO:0044281//small molecule metabolic process",GO:0016401//palmitoyl-CoA oxidase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0000062//fatty-acyl-CoA binding;GO:0050660//flavin adenine dinucleotide binding;GO:0004466//long-chain-acyl-CoA dehydrogenase activity,K00255//Fatty acid metabolism;Metabolic pathways;PPAR signaling pathway
330,122,0,0,0,18,19,69,0,42,0,0,0,BIRC3;baculoviral IAP repeat containing 3,GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042326//negative regulation of phosphorylation;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0007283//spermatogenesis;GO:2000116//regulation of cysteine-type endopeptidase activity;GO:0060546//negative regulation of necroptotic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0045088//regulation of innate immune response;GO:0060544//regulation of necroptotic process;GO:0031398//positive regulation of protein ubiquitination;GO:0034121//regulation of toll-like receptor signaling pathway;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0070266//necroptotic process;GO:0050727//regulation of inflammatory response;GO:0002224//toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination;GO:0038061//NIK/NF-kappaB signaling;GO:0045087//innate immune response;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0039535//regulation of RIG-I signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,K16060//Apoptosis;Toxoplasmosis;Focal adhesion;NF-kappa B signaling pathway;Pathways in cancer;NOD-like receptor signaling pathway;Small cell lung cancer;Ubiquitin mediated proteolysis;Transcriptional misregulation in cancer
3300,88,21,5,4,50,28,0,0,18,0,0,0,"DNAJB2;DnaJ (Hsp40) homolog, subfamily B, member 2",GO:0005829//cytosol;GO:0016234//inclusion body;GO:0000502//proteasome complex;GO:0005634//nucleus,GO:0031398//positive regulation of protein ubiquitination;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0090086//negative regulation of protein deubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0090084//negative regulation of inclusion body assembly;GO:0008219//cell death;GO:0006986//response to unfolded protein;GO:0030308//negative regulation of cell growth;GO:0008285//negative regulation of cell proliferation;GO:0042026//protein refolding;GO:0006457//protein folding,GO:0051087//chaperone binding;GO:0070628//proteasome binding;GO:0051082//unfolded protein binding;GO:0030544//Hsp70 protein binding;GO:0005515//protein binding;GO:0031593//polyubiquitin binding,K09508//Protein processing in endoplasmic reticulum
3301,0,1,0,86,227,5,0,0,7,0,0,0,"DNAJA1;DnaJ (Hsp40) homolog, subfamily A, member 1",GO:0000151//ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane,"GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0030317//sperm motility;GO:0051223//regulation of protein transport;GO:0031397//negative regulation of protein ubiquitination;GO:0043508//negative regulation of JUN kinase activity;GO:0009408//response to heat;GO:0006457//protein folding;GO:0042769//DNA damage response, detection of DNA damage;GO:0070585//protein localization to mitochondrion;GO:0030521//androgen receptor signaling pathway;GO:0006986//response to unfolded protein",GO:0031625//ubiquitin protein ligase binding;GO:0030544//Hsp70 protein binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0005524//ATP binding;GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0001664//G-protein coupled receptor binding,K09502//Protein processing in endoplasmic reticulum
3303,0,0,0,0,1,0,0,0,1,0,0,0,HSPA1A;heat shock 70kDa protein 1A,-,-,-,K03283//Prion diseases;Protein processing in endoplasmic reticulum;Toxoplasmosis;MAPK signaling pathway;Epstein-Barr virus infection;Antigen processing and presentation;Measles;Endocytosis;Spliceosome;Influenza A;Legionellosis
3304,0,1,0,0,0,0,0,0,0,0,0,3,HSPA1B;heat shock 70kDa protein 1B,GO:0005783//endoplasmic reticulum;GO:0016234//inclusion body;GO:0016235//aggresome;GO:0031982//vesicle;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005814//centriole;GO:0008180//COP9 signalosome;GO:0005925//focal adhesion;GO:0005634//nucleus,GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006200//ATP catabolic process;GO:0006986//response to unfolded protein;GO:0060548//negative regulation of cell death;GO:0031397//negative regulation of protein ubiquitination;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0070370//cellular heat acclimation;GO:0090084//negative regulation of inclusion body assembly;GO:0034605//cellular response to heat;GO:0030308//negative regulation of cell growth;GO:0009615//response to virus;GO:0006402//mRNA catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0010941//regulation of cell death;GO:0045648//positive regulation of erythrocyte differentiation;GO:0042026//protein refolding,"GO:0044183//protein binding involved in protein folding;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0001618//virus receptor activity;GO:0042623//ATPase activity, coupled;GO:0001664//G-protein coupled receptor binding;GO:0003725//double-stranded RNA binding;GO:0016887//ATPase activity;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding;GO:0047485//protein N-terminus binding;GO:0019899//enzyme binding",K03283//Legionellosis;Influenza A;Spliceosome;Endocytosis;Measles;Antigen processing and presentation;Epstein-Barr virus infection;Protein processing in endoplasmic reticulum;Prion diseases;Toxoplasmosis;MAPK signaling pathway
3305,0,0,0,0,0,0,0,0,1,0,0,0,HSPA1L;heat shock 70kDa protein 1-like,GO:0005759//mitochondrial matrix;GO:0044297//cell body;GO:0072562//blood microparticle;GO:0002199//zona pellucida receptor complex;GO:0008180//COP9 signalosome;GO:0005829//cytosol,GO:0006986//response to unfolded protein;GO:0007339//binding of sperm to zona pellucida;GO:0042026//protein refolding,GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding,K03283//Endocytosis;Spliceosome;Influenza A;Legionellosis;Protein processing in endoplasmic reticulum;Toxoplasmosis;Prion diseases;MAPK signaling pathway;Epstein-Barr virus infection;Measles;Antigen processing and presentation
3306,0,0,1,0,0,0,0,0,10,0,0,0,HSPA2;heat shock 70kDa protein 2,GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0016020//membrane;GO:0001673//male germ cell nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0036128//CatSper complex;GO:0005634//nucleus;GO:0000795//synaptonemal complex,GO:0006986//response to unfolded protein;GO:0031662//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle;GO:0070194//synaptonemal complex disassembly;GO:0090084//negative regulation of inclusion body assembly;GO:0007286//spermatid development;GO:0007140//male meiosis;GO:0007141//male meiosis I;GO:0042026//protein refolding,GO:0019899//enzyme binding;GO:0051861//glycolipid binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,K03283//Legionellosis;Influenza A;Spliceosome;Endocytosis;Measles;Antigen processing and presentation;Epstein-Barr virus infection;MAPK signaling pathway;Protein processing in endoplasmic reticulum;Prion diseases;Toxoplasmosis
3308,0,55,3,43,213,0,19,0,52,0,0,0,HSPA4;heat shock 70kDa protein 4,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0006986//response to unfolded protein;GO:0051131//chaperone-mediated protein complex assembly;GO:0045040//protein import into mitochondrial outer membrane,GO:0005524//ATP binding,K09489//Antigen processing and presentation
3309,58,43,2,8,55,1,7,97,20,0,0,0,"HSPA5;heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)",GO:0008180//COP9 signalosome;GO:0030496//midbody;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005925//focal adhesion;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0016020//membrane;GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042149//cellular response to glucose starvation;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0035437//maintenance of protein localization in endoplasmic reticulum;GO:0071236//cellular response to antibiotic;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0021680//cerebellar Purkinje cell layer development;GO:0060904//regulation of protein folding in endoplasmic reticulum;GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0044267//cellular protein metabolic process;GO:0071353//cellular response to interleukin-4;GO:0021762//substantia nigra development;GO:0021589//cerebellum structural organization;GO:0006200//ATP catabolic process;GO:0006983//ER overload response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0030168//platelet activation;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0043022//ribosome binding;GO:0005515//protein binding;GO:0051787//misfolded protein binding;GO:0051082//unfolded protein binding;GO:0005509//calcium ion binding;GO:0051087//chaperone binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0001948//glycoprotein binding;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0016887//ATPase activity,K09490//Prion diseases;Protein processing in endoplasmic reticulum;Protein export;Antigen processing and presentation
331,0,17,0,66,185,33,0,1,73,0,3,0,XIAP;X-linked inhibitor of apoptosis,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0005829//cytosol,GO:0006915//apoptotic process;GO:1902530//positive regulation of protein linear polyubiquitination;GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045088//regulation of innate immune response;GO:0055070//copper ion homeostasis;GO:0042127//regulation of cell proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0031398//positive regulation of protein ubiquitination;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0050727//regulation of inflammatory response;GO:0051402//neuron apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070424//regulation of nucleotide-binding oligomerization domain containing signaling pathway;GO:0030510//regulation of BMP signaling pathway,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0002020//protease binding;GO:0097110//scaffold protein binding,K04725//Ubiquitin mediated proteolysis;Small cell lung cancer;HTLV-I infection;NF-kappa B signaling pathway;Pathways in cancer;Focal adhesion;Apoptosis;Toxoplasmosis
3310,0,0,0,0,0,0,0,0,31,0,6,311,HSPA6;heat shock 70kDa protein 6 (HSP70B'),GO:0005737//cytoplasm;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0005814//centriole,GO:0006200//ATP catabolic process;GO:0006986//response to unfolded protein;GO:0070370//cellular heat acclimation;GO:0034605//cellular response to heat;GO:0042026//protein refolding,"GO:0005524//ATP binding;GO:0042623//ATPase activity, coupled;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding",K03283//Antigen processing and presentation;Measles;Epstein-Barr virus infection;MAPK signaling pathway;Prion diseases;Protein processing in endoplasmic reticulum;Toxoplasmosis;Legionellosis;Influenza A;Spliceosome;Endocytosis
3311,0,1,0,0,0,0,0,28,0,0,0,0,HSPA7;heat shock 70kDa protein 7 (HSP70B),GO:0070062//extracellular vesicular exosome;GO:0008180//COP9 signalosome;GO:0072562//blood microparticle,GO:0006950//response to stress,GO:0005524//ATP binding,K03283//Epstein-Barr virus infection;Measles;Antigen processing and presentation;Toxoplasmosis;Prion diseases;Protein processing in endoplasmic reticulum;MAPK signaling pathway;Influenza A;Legionellosis;Endocytosis;Spliceosome
3312,0,511,11,321,1881,0,1,0,31,0,14,0,HSPA8;heat shock 70kDa protein 8,GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0072562//blood microparticle;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0000151//ubiquitin ligase complex;GO:0005730//nucleolus;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0000974//Prp19 complex;GO:0042470//melanosome;GO:0005622//intracellular;GO:0005829//cytosol,"GO:1902904//negative regulation of fibril organization;GO:0042026//protein refolding;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006351//transcription, DNA-templated;GO:0006457//protein folding;GO:0051726//regulation of cell cycle;GO:0072318//clathrin coat disassembly;GO:0007411//axon guidance;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0007269//neurotransmitter secretion;GO:0006397//mRNA processing;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0016032//viral process;GO:0006986//response to unfolded protein;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006200//ATP catabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0061024//membrane organization;GO:0007268//synaptic transmission","GO:0031625//ubiquitin protein ligase binding;GO:0016887//ATPase activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0023026//MHC class II protein complex binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0051082//unfolded protein binding;GO:0042623//ATPase activity, coupled;GO:0001664//G-protein coupled receptor binding",K03283//Legionellosis;Influenza A;Spliceosome;Endocytosis;Measles;Antigen processing and presentation;Epstein-Barr virus infection;Protein processing in endoplasmic reticulum;Toxoplasmosis;Prion diseases;MAPK signaling pathway
3313,0,98,0,30,220,0,0,61,3,1,6,261,HSPA9;heat shock 70kDa protein 9 (mortalin),GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0006611//protein export from nucleus;GO:0006457//protein folding;GO:0006626//protein targeting to mitochondrion;GO:0043066//negative regulation of apoptotic process;GO:0044267//cellular protein metabolic process,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0019899//enzyme binding,K04043//RNA degradation;Aminoacyl-tRNA biosynthesis;Two-component system;Pantothenate and CoA biosynthesis;Tuberculosis
3315,0,1,0,10,31,0,0,1,14,0,0,0,HSPB1;heat shock 27kDa protein 1,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005819//spindle;GO:0000502//proteasome complex;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001895//retina homeostasis;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0006928//cellular component movement;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0006986//response to unfolded protein;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0070527//platelet aggregation;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0009615//response to virus;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006446//regulation of translational initiation;GO:0008219//cell death;GO:0045766//positive regulation of angiogenesis;GO:0006469//negative regulation of protein kinase activity;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0032731//positive regulation of interleukin-1 beta production,GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005080//protein kinase C binding;GO:0043130//ubiquitin binding;GO:0008426//protein kinase C inhibitor activity,K04455//MAPK signaling pathway;Amoebiasis;Epstein-Barr virus infection;VEGF signaling pathway
3316,0,0,0,0,0,1,0,0,0,0,0,0,HSPB2;heat shock 27kDa protein 2,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043085//positive regulation of catalytic activity;GO:0006986//response to unfolded protein,GO:0008047//enzyme activator activity;GO:0005515//protein binding,K09543//Epstein-Barr virus infection
332,0,0,0,0,0,0,0,0,27,0,0,0,BIRC5;baculoviral IAP repeat containing 5,"GO:0005874//microtubule;GO:0031021//interphase microtubule organizing center;GO:0005876//spindle microtubule;GO:0000775//chromosome, centromeric region;GO:0032133//chromosome passenger complex;GO:0005634//nucleus;GO:0005814//centriole;GO:0005829//cytosol;GO:0030496//midbody;GO:0005819//spindle;GO:0000228//nuclear chromosome;GO:0005737//cytoplasm;GO:0000777//condensed chromosome kinetochore;GO:0005881//cytoplasmic microtubule","GO:0000910//cytokinesis;GO:0031577//spindle checkpoint;GO:0007067//mitotic nuclear division;GO:0006915//apoptotic process;GO:0031536//positive regulation of exit from mitosis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010951//negative regulation of endopeptidase activity;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0031503//protein complex localization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051303//establishment of chromosome localization;GO:0051301//cell division;GO:0008284//positive regulation of cell proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process",GO:0008270//zinc ion binding;GO:0050897//cobalt ion binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0008536//Ran GTPase binding;GO:0015631//tubulin binding;GO:0048037//cofactor binding;GO:0042802//identical protein binding;GO:0008017//microtubule binding;GO:0019899//enzyme binding;GO:0051087//chaperone binding,K08731//Pathways in cancer;Colorectal cancer
3320,106,439,6,763,2358,0,27,92,42,0,0,0,"HSP90AA1;heat shock protein 90kDa alpha (cytosolic), class A member 1",GO:0005737//cytoplasm;GO:0071682//endocytic vesicle lumen;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0016020//membrane;GO:0042470//melanosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0042026//protein refolding;GO:0046209//nitric oxide metabolic process;GO:0007411//axon guidance;GO:0045087//innate immune response;GO:0006839//mitochondrial transport;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0044281//small molecule metabolic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0051131//chaperone-mediated protein complex assembly;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006986//response to unfolded protein;GO:0007165//signal transduction;GO:0006200//ATP catabolic process;GO:0045040//protein import into mitochondrial outer membrane,GO:0042803//protein homodimerization activity;GO:0023026//MHC class II protein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0051082//unfolded protein binding;GO:0042802//identical protein binding;GO:0016887//ATPase activity;GO:0030235//nitric-oxide synthase regulator activity;GO:0030911//TPR domain binding;GO:0005524//ATP binding,K04079//Pathways in cancer;Protein processing in endoplasmic reticulum;Antigen processing and presentation;Prostate cancer;Progesterone-mediated oocyte maturation;NOD-like receptor signaling pathway;Plant-pathogen interaction
3321,0,0,0,0,1,13,6,0,32,16,23,0,"IGSF3;immunoglobulin superfamily, member 3",GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0032808//lacrimal gland development,-,-
3326,0,373,56,361,1362,0,0,1,33,8,1,0,"HSP90AB1;heat shock protein 90kDa alpha (cytosolic), class B member 1",GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0042470//melanosome;GO:0016234//inclusion body;GO:0008180//COP9 signalosome;GO:0005739//mitochondrion;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol,"GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0043524//negative regulation of neuron apoptotic process;GO:0071353//cellular response to interleukin-4;GO:0006986//response to unfolded protein;GO:0009651//response to salt stress;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0001890//placenta development;GO:0071407//cellular response to organic cyclic compound;GO:0007411//axon guidance;GO:0032092//positive regulation of protein binding;GO:0006457//protein folding;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0045793//positive regulation of cell size;GO:0045087//innate immune response;GO:0071902//positive regulation of protein serine/threonine kinase activity",GO:0019901//protein kinase binding;GO:0002134//UTP binding;GO:0003725//double-stranded RNA binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0005525//GTP binding;GO:0017098//sulfonylurea receptor binding;GO:0030911//TPR domain binding;GO:0005524//ATP binding;GO:0023026//MHC class II protein complex binding;GO:0044325//ion channel binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0002135//CTP binding;GO:0051082//unfolded protein binding;GO:0032564//dATP binding,K04079//Plant-pathogen interaction;NOD-like receptor signaling pathway;Progesterone-mediated oocyte maturation;Antigen processing and presentation;Prostate cancer;Protein processing in endoplasmic reticulum;Pathways in cancer
3329,0,80,20,140,223,0,3,161,53,2,149,0,HSPD1;heat shock 60kDa protein 1 (chaperonin),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0043234//protein complex;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0016020//membrane;GO:0030135//coated vesicle;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005905//coated pit;GO:0046696//lipopolysaccharide receptor complex,GO:0032733//positive regulation of interleukin-10 production;GO:0042026//protein refolding;GO:0002368//B cell cytokine production;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0002842//positive regulation of T cell mediated immune response to tumor cell;GO:0050821//protein stabilization;GO:0050870//positive regulation of T cell activation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042100//B cell proliferation;GO:0006458//'de novo' protein folding;GO:0032729//positive regulation of interferon-gamma production;GO:0032727//positive regulation of interferon-alpha production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0051131//chaperone-mediated protein complex assembly;GO:0032735//positive regulation of interleukin-12 production;GO:0043065//positive regulation of apoptotic process;GO:0051604//protein maturation;GO:0016032//viral process;GO:0032755//positive regulation of interleukin-6 production;GO:0048291//isotype switching to IgG isotypes;GO:0006986//response to unfolded protein;GO:0042113//B cell activation;GO:0006200//ATP catabolic process,GO:0051087//chaperone binding;GO:0005524//ATP binding;GO:0003697//single-stranded DNA binding;GO:0003688//DNA replication origin binding;GO:0002039//p53 binding;GO:0003725//double-stranded RNA binding;GO:0016887//ATPase activity;GO:0001530//lipopolysaccharide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,K04077//DNA replication;Vitamin B6 metabolism;Metabolic pathways;RNA degradation;Nucleotide excision repair;Legionellosis;Base excision repair;Tuberculosis;Mismatch repair;Type I diabetes mellitus
333,80,0,0,0,6,3,0,0,16,0,20,0,APLP1;amyloid beta (A4) precursor-like protein 1,GO:0005604//basement membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0030818//negative regulation of cAMP biosynthetic process;GO:0030198//extracellular matrix organization;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0006897//endocytosis;GO:0006915//apoptotic process;GO:0071874//cellular response to norepinephrine stimulus;GO:0007399//nervous system development;GO:0009887//organ morphogenesis;GO:0006378//mRNA polyadenylation;GO:0030900//forebrain development;GO:0007155//cell adhesion;GO:0006417//regulation of translation,GO:0031694//alpha-2A adrenergic receptor binding;GO:0046914//transition metal ion binding;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0031696//alpha-2C adrenergic receptor binding;GO:0031695//alpha-2B adrenergic receptor binding,-
3336,0,0,0,0,26,0,0,0,0,0,0,0,HSPE1;heat shock 10kDa protein 1,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006986//response to unfolded protein;GO:0006457//protein folding;GO:0001649//osteoblast differentiation,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0051087//chaperone binding,-
3337,0,1,0,0,10,0,0,0,0,0,0,0,"DNAJB1;DnaJ (Hsp40) homolog, subfamily B, member 1",GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0070389//chaperone cofactor-dependent protein refolding;GO:0006986//response to unfolded protein;GO:0051085//chaperone mediated protein folding requiring cofactor;GO:0032781//positive regulation of ATPase activity;GO:0090084//negative regulation of inclusion body assembly,GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0051117//ATPase binding;GO:0030544//Hsp70 protein binding;GO:0005515//protein binding;GO:0001671//ATPase activator activity,K09507//Protein processing in endoplasmic reticulum;Influenza A
3338,0,1,0,9,22,1,0,42,8,0,0,0,"DNAJC4;DnaJ (Hsp40) homolog, subfamily C, member 4",GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0006457//protein folding;GO:0006986//response to unfolded protein,GO:0005515//protein binding;GO:0051082//unfolded protein binding,-
3339,326,0,1,0,45,55,78,115,197,317,97,314,HSPG2;heparan sulfate proteoglycan 2,GO:0043202//lysosomal lumen;GO:0005605//basal lamina;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005925//focal adhesion,"GO:0006024//glycosaminoglycan biosynthetic process;GO:0001525//angiogenesis;GO:0044281//small molecule metabolic process;GO:0001523//retinoid metabolic process;GO:0030198//extracellular matrix organization;GO:0007420//brain development;GO:0002062//chondrocyte differentiation;GO:0048738//cardiac muscle tissue development;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0008104//protein localization;GO:0007603//phototransduction, visible light;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0030203//glycosaminoglycan metabolic process;GO:0022617//extracellular matrix disassembly;GO:0005975//carbohydrate metabolic process;GO:0001958//endochondral ossification;GO:0042157//lipoprotein metabolic process;GO:0048704//embryonic skeletal system morphogenesis",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding,K06255//ECM-receptor interaction
333926,0,0,0,0,0,0,0,0,1,0,0,0,"PPM1J;protein phosphatase, Mg2+/Mn2+ dependent, 1J",-,GO:0006470//protein dephosphorylation,GO:0004722//protein serine/threonine phosphatase activity,-
333929,0,0,0,8,10,0,0,1,18,0,36,0,SNAI3;snail family zinc finger 3,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005507//copper ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
334,0,0,0,21,4,8,20,0,5,122,0,0,APLP2;amyloid beta (A4) precursor-like protein 2,GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0008203//cholesterol metabolic process;GO:0030900//forebrain development;GO:0050885//neuromuscular process controlling balance;GO:0010951//negative regulation of endopeptidase activity;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0001967//suckling behavior;GO:0007617//mating behavior;GO:0030198//extracellular matrix organization;GO:0006878//cellular copper ion homeostasis;GO:0030901//midbrain development;GO:0007626//locomotory behavior;GO:0043393//regulation of protein binding,GO:0046914//transition metal ion binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0042802//identical protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,-
3340,0,0,1,0,0,0,0,0,4,0,0,0,NDST1;N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0007224//smoothened signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0030210//heparin biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030901//midbrain development;GO:0006954//inflammatory response;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007585//respiratory gaseous exchange;GO:0000271//polysaccharide biosynthetic process;GO:0030900//forebrain development;GO:0048702//embryonic neurocranium morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0000165//MAPK cascade,GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0019213//deacetylase activity,K02576//Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
3344,0,1,0,22,4,12,6,0,8,0,5,0,FOXN2;forkhead box N2,GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
335,0,0,0,0,0,0,0,54,10,0,0,0,APOA1;apolipoprotein A-I,GO:0071682//endocytic vesicle lumen;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0034364//high-density lipoprotein particle;GO:0031982//vesicle;GO:0031410//cytoplasmic vesicle;GO:0034366//spherical high-density lipoprotein particle;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0034774//secretory granule lumen;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0034361//very-low-density lipoprotein particle,"GO:0050821//protein stabilization;GO:0030325//adrenal gland development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008203//cholesterol metabolic process;GO:0001932//regulation of protein phosphorylation;GO:0055085//transmembrane transport;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0007603//phototransduction, visible light;GO:0043691//reverse cholesterol transport;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0010873//positive regulation of cholesterol esterification;GO:0031100//organ regeneration;GO:0042158//lipoprotein biosynthetic process;GO:0042493//response to drug;GO:0001523//retinoid metabolic process;GO:0033700//phospholipid efflux;GO:0014012//peripheral nervous system axon regeneration;GO:0043627//response to estrogen;GO:0070371//ERK1 and ERK2 cascade;GO:0060761//negative regulation of response to cytokine stimulus;GO:0050728//negative regulation of inflammatory response;GO:0051347//positive regulation of transferase activity;GO:0018206//peptidyl-methionine modification;GO:0007584//response to nutrient;GO:0034380//high-density lipoprotein particle assembly;GO:0070508//cholesterol import;GO:0007229//integrin-mediated signaling pathway;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0034375//high-density lipoprotein particle remodeling;GO:0060192//negative regulation of lipase activity;GO:0042157//lipoprotein metabolic process;GO:0008211//glucocorticoid metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0043534//blood vessel endothelial cell migration;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0006656//phosphatidylcholine biosynthetic process;GO:0060354//negative regulation of cell adhesion molecule production;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0033344//cholesterol efflux;GO:0001935//endothelial cell proliferation;GO:0030300//regulation of intestinal cholesterol absorption;GO:0034384//high-density lipoprotein particle clearance;GO:0019915//lipid storage;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0002576//platelet degranulation;GO:0042632//cholesterol homeostasis;GO:0051345//positive regulation of hydrolase activity;GO:0007596//blood coagulation;GO:0050919//negative chemotaxis;GO:0006695//cholesterol biosynthetic process;GO:0030301//cholesterol transport;GO:0070328//triglyceride homeostasis;GO:0050713//negative regulation of interleukin-1 beta secretion;GO:0055091//phospholipid homeostasis;GO:0002740//negative regulation of cytokine secretion involved in immune response;GO:0030168//platelet activation;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0018158//protein oxidation",GO:0005543//phospholipid binding;GO:0055102//lipase inhibitor activity;GO:0005515//protein binding;GO:0034190//apolipoprotein receptor binding;GO:0001540//beta-amyloid binding;GO:0045499//chemorepellent activity;GO:0070653//high-density lipoprotein particle receptor binding;GO:0034191//apolipoprotein A-I receptor binding;GO:0008035//high-density lipoprotein particle binding;GO:0042802//identical protein binding;GO:0015485//cholesterol binding;GO:0017127//cholesterol transporter activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0019899//enzyme binding;GO:0005548//phospholipid transporter activity,K08757//PPAR signaling pathway;Vitamin digestion and absorption;Fat digestion and absorption;African trypanosomiasis
3350,101,0,0,0,0,0,0,0,0,1,0,1,"HTR1A;5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007210//serotonin receptor signaling pathway;GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0008283//cell proliferation;GO:0042053//regulation of dopamine metabolic process;GO:0035640//exploration behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0042428//serotonin metabolic process;GO:0014062//regulation of serotonin secretion;GO:0008284//positive regulation of cell proliferation;GO:0046883//regulation of hormone secretion;GO:0001662//behavioral fear response;GO:0050795//regulation of behavior,GO:0004993//serotonin receptor activity;GO:0005515//protein binding,K04153//Neuroactive ligand-receptor interaction;Serotonergic synapse
3351,0,0,0,0,0,0,36,0,11,0,3,0,"HTR1B;5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled",GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,"GO:0007198//adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0014063//negative regulation of serotonin secretion;GO:0007268//synaptic transmission;GO:0046849//bone remodeling;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0071312//cellular response to alkaloid;GO:0050795//regulation of behavior;GO:0042756//drinking behavior;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0035690//cellular response to drug;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0045471//response to ethanol;GO:0042310//vasoconstriction;GO:0051385//response to mineralocorticoid;GO:0014059//regulation of dopamine secretion;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0002031//G-protein coupled receptor internalization;GO:0042220//response to cocaine;GO:0071502//cellular response to temperature stimulus",GO:0051378//serotonin binding;GO:0008144//drug binding;GO:0004993//serotonin receptor activity,K04153//Neuroactive ligand-receptor interaction;Serotonergic synapse
3352,0,0,0,0,0,0,0,0,0,0,8,0,"HTR1D;5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0040012//regulation of locomotion;GO:0009636//response to toxic substance;GO:0050795//regulation of behavior;GO:0014827//intestine smooth muscle contraction;GO:0007268//synaptic transmission;GO:0042310//vasoconstriction;GO:0007210//serotonin receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger",GO:0051378//serotonin binding;GO:0004993//serotonin receptor activity,K04153//Neuroactive ligand-receptor interaction;Serotonergic synapse
3354,96,0,0,0,0,13,0,0,33,3,0,1,"HTR1E;5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007210//serotonin receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0030815//negative regulation of cAMP metabolic process",GO:0051378//serotonin binding;GO:0004930//G-protein coupled receptor activity;GO:0004993//serotonin receptor activity,K04153//Neuroactive ligand-receptor interaction;Serotonergic synapse
3355,0,0,0,0,0,10,0,0,0,0,0,0,"HTR1F;5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007268//synaptic transmission;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007210//serotonin receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger",GO:0004993//serotonin receptor activity;GO:0051378//serotonin binding,K04153//Neuroactive ligand-receptor interaction;Serotonergic synapse
3356,0,0,0,0,0,0,0,0,40,0,0,0,"HTR2A;5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled",GO:0043025//neuronal cell body;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0070852//cell body fiber;GO:0005829//cytosol;GO:0030424//axon,"GO:0014059//regulation of dopamine secretion;GO:0045821//positive regulation of glycolytic process;GO:0007202//activation of phospholipase C activity;GO:0001659//temperature homeostasis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0043267//negative regulation of potassium ion transport;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0048148//behavioral response to cocaine;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0042493//response to drug;GO:0008219//cell death;GO:0008284//positive regulation of cell proliferation;GO:0006874//cellular calcium ion homeostasis;GO:0045907//positive regulation of vasoconstriction;GO:0007268//synaptic transmission;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007210//serotonin receptor signaling pathway;GO:0050795//regulation of behavior;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0007613//memory;GO:0046883//regulation of hormone secretion;GO:0014824//artery smooth muscle contraction;GO:0007568//aging;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0014832//urinary bladder smooth muscle contraction;GO:0030431//sleep","GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding;GO:0001965//G-protein alpha-subunit binding;GO:0032403//protein complex binding;GO:0008144//drug binding;GO:0051378//serotonin binding;GO:0004993//serotonin receptor activity",K04157//Gap junction;Serotonergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction
3357,0,46,0,0,0,0,0,0,33,0,0,0,"HTR2B;5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled",GO:0043005//neuron projection;GO:0030054//cell junction;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032320//positive regulation of Ras GTPase activity;GO:0070371//ERK1 and ERK2 cascade;GO:0003300//cardiac muscle hypertrophy;GO:0010507//negative regulation of autophagy;GO:0048598//embryonic morphogenesis;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:0019722//calcium-mediated signaling;GO:0016310//phosphorylation;GO:0070528//protein kinase C signaling;GO:0001819//positive regulation of cytokine production;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0007202//activation of phospholipase C activity;GO:0001938//positive regulation of endothelial cell proliferation;GO:0014033//neural crest cell differentiation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042310//vasoconstriction;GO:0042493//response to drug;GO:0006874//cellular calcium ion homeostasis;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0007210//serotonin receptor signaling pathway;GO:0060548//negative regulation of cell death;GO:0001755//neural crest cell migration;GO:0051781//positive regulation of cell division;GO:0007610//behavior;GO:0003007//heart morphogenesis;GO:0050795//regulation of behavior;GO:0050715//positive regulation of cytokine secretion;GO:0051209//release of sequestered calcium ion into cytosol;GO:0043066//negative regulation of apoptotic process;GO:0002031//G-protein coupled receptor internalization;GO:0014827//intestine smooth muscle contraction;GO:0008284//positive regulation of cell proliferation;GO:0006182//cGMP biosynthetic process;GO:0071502//cellular response to temperature stimulus,GO:0001965//G-protein alpha-subunit binding;GO:0005099//Ras GTPase activator activity;GO:0004993//serotonin receptor activity;GO:0008144//drug binding;GO:0051378//serotonin binding,K04157//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Serotonergic synapse;Gap junction
3358,0,0,0,0,0,0,24,0,21,0,0,0,"HTR2C;5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0032098//regulation of appetite;GO:0007208//phospholipase C-activating serotonin receptor signaling pathway;GO:0031644//regulation of neurological system process;GO:0051209//release of sequestered calcium ion into cytosol;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0006182//cGMP biosynthetic process;GO:0007626//locomotory behavior;GO:0042493//response to drug;GO:0007268//synaptic transmission;GO:0043397//regulation of corticotropin-releasing hormone secretion;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0007210//serotonin receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007631//feeding behavior;GO:0001662//behavioral fear response;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process,"GO:0071886//1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding;GO:0051378//serotonin binding;GO:0008144//drug binding;GO:0004993//serotonin receptor activity;GO:0001587//Gq/11-coupled serotonin receptor activity",K04157//Gap junction;Serotonergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction
3359,0,0,0,0,1,0,6,0,44,0,0,2,"HTR3A;5-hydroxytryptamine (serotonin) receptor 3A, ionotropic",GO:0005886//plasma membrane;GO:0030424//axon;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,GO:0006812//cation transport;GO:0007210//serotonin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0045471//response to ethanol;GO:0071363//cellular response to growth factor stimulus;GO:0055085//transmembrane transport;GO:0007586//digestion;GO:0042220//response to cocaine,GO:0005232//serotonin-activated cation-selective channel activity;GO:0004872//receptor activity;GO:0051378//serotonin binding;GO:0005249//voltage-gated potassium channel activity;GO:0004993//serotonin receptor activity,K04819//Serotonergic synapse
3360,0,0,0,0,0,31,0,0,35,0,0,0,"HTR4;5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled",GO:0005886//plasma membrane;GO:0005768//endosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,"GO:0007210//serotonin receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008284//positive regulation of cell proliferation;GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032098//regulation of appetite",GO:0004993//serotonin receptor activity,K04160//Serotonergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction
3361,0,0,0,0,0,23,23,0,47,0,7,0,"HTR5A;5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled",GO:0005794//Golgi apparatus;GO:0005791//rough endoplasmic reticulum;GO:0043204//perikaryon;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007210//serotonin receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032355//response to estradiol;GO:0021766//hippocampus development;GO:0019933//cAMP-mediated signaling",GO:0004993//serotonin receptor activity,K04161//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Serotonergic synapse
3362,0,0,0,0,0,0,0,71,7,0,8,0,"HTR6;5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled",GO:0005887//integral component of plasma membrane;GO:0005929//cilium;GO:0005886//plasma membrane;GO:0030425//dendrite,"GO:0032355//response to estradiol;GO:0014053//negative regulation of gamma-aminobutyric acid secretion;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0033603//positive regulation of dopamine secretion;GO:0042493//response to drug;GO:0007268//synaptic transmission;GO:0007612//learning;GO:0014058//negative regulation of acetylcholine secretion, neurotransmission;GO:0007420//brain development;GO:0007210//serotonin receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0014050//negative regulation of glutamate secretion;GO:0060291//long-term synaptic potentiation",GO:0005515//protein binding;GO:0004969//histamine receptor activity;GO:0004993//serotonin receptor activity,K04162//Neuroactive ligand-receptor interaction;Serotonergic synapse;Calcium signaling pathway
3363,0,0,0,0,0,11,43,0,19,198,0,538,"HTR7;5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007210//serotonin receptor signaling pathway;GO:0006939//smooth muscle contraction;GO:0042310//vasoconstriction;GO:0008015//blood circulation;GO:0007268//synaptic transmission;GO:0007623//circadian rhythm",GO:0004993//serotonin receptor activity,K04163//Neuroactive ligand-receptor interaction;Serotonergic synapse;Calcium signaling pathway
3364,37,0,0,1,58,1,0,0,24,0,0,0,HUS1;HUS1 checkpoint homolog (S. pombe),GO:0030896//checkpoint clamp complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0009411//response to UV;GO:0000724//double-strand break repair via homologous recombination;GO:0006468//protein phosphorylation;GO:0001932//regulation of protein phosphorylation;GO:0006260//DNA replication;GO:0006974//cellular response to DNA damage stimulus;GO:0071479//cellular response to ionizing radiation;GO:0000077//DNA damage checkpoint;GO:0007093//mitotic cell cycle checkpoint;GO:0009790//embryo development;GO:0006281//DNA repair;GO:0008156//negative regulation of DNA replication,GO:0005515//protein binding,-
337,0,0,0,0,0,0,11,43,12,0,0,0,APOA4;apolipoprotein A-IV,GO:0005788//endoplasmic reticulum lumen;GO:0034361//very-low-density lipoprotein particle;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0042627//chylomicron;GO:0034364//high-density lipoprotein particle;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,"GO:0010898//positive regulation of triglyceride catabolic process;GO:0034371//chylomicron remodeling;GO:0043691//reverse cholesterol transport;GO:0007603//phototransduction, visible light;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0042744//hydrogen peroxide catabolic process;GO:0001523//retinoid metabolic process;GO:0010873//positive regulation of cholesterol esterification;GO:0055088//lipid homeostasis;GO:0035634//response to stilbenoid;GO:0030300//regulation of intestinal cholesterol absorption;GO:0006982//response to lipid hydroperoxide;GO:0033344//cholesterol efflux;GO:0002227//innate immune response in mucosa;GO:0034445//negative regulation of plasma lipoprotein particle oxidation;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0007159//leukocyte cell-cell adhesion;GO:0044281//small molecule metabolic process;GO:0019430//removal of superoxide radicals;GO:0042632//cholesterol homeostasis;GO:0044240//multicellular organismal lipid catabolic process;GO:0006869//lipid transport;GO:0033700//phospholipid efflux;GO:0046470//phosphatidylcholine metabolic process;GO:0034378//chylomicron assembly;GO:0032374//regulation of cholesterol transport;GO:0042157//lipoprotein metabolic process;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0034375//high-density lipoprotein particle remodeling",GO:0016209//antioxidant activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0008289//lipid binding;GO:0017127//cholesterol transporter activity;GO:0042803//protein homodimerization activity;GO:0031210//phosphatidylcholine binding;GO:0005319//lipid transporter activity;GO:0005507//copper ion binding,K08760//Fat digestion and absorption;Vitamin digestion and absorption
3371,0,0,0,0,0,14,20,0,79,242,0,0,TNC;tenascin C,GO:0031012//extracellular matrix;GO:0005614//interstitial matrix;GO:0005925//focal adhesion;GO:0005576//extracellular region;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005604//basement membrane,GO:0001649//osteoblast differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009611//response to wounding;GO:0060740//prostate gland epithelium morphogenesis;GO:0009612//response to mechanical stimulus;GO:0007162//negative regulation of cell adhesion;GO:0071300//cellular response to retinoic acid;GO:0007155//cell adhesion;GO:0014012//peripheral nervous system axon regeneration;GO:0008284//positive regulation of cell proliferation;GO:0071799//cellular response to prostaglandin D stimulus;GO:0030198//extracellular matrix organization;GO:0071305//cellular response to vitamin D;GO:0007528//neuromuscular junction development;GO:0060447//bud outgrowth involved in lung branching;GO:0042060//wound healing;GO:0060739//mesenchymal-epithelial cell signaling involved in prostate gland development;GO:0045471//response to ethanol;GO:0010628//positive regulation of gene expression;GO:0071774//response to fibroblast growth factor,GO:0045545//syndecan binding,K06252//Focal adhesion;ECM-receptor interaction
3373,0,0,0,0,0,0,0,0,19,0,17,0,HYAL1;hyaluronoglucosaminidase 1,GO:0036117//hyaluranon cable;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0043202//lysosomal lumen,GO:0030307//positive regulation of cell growth;GO:0030213//hyaluronan biosynthetic process;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0060272//embryonic skeletal joint morphogenesis;GO:0071493//cellular response to UV-B;GO:0050679//positive regulation of epithelial cell proliferation;GO:0030308//negative regulation of cell growth;GO:0009615//response to virus;GO:0030204//chondroitin sulfate metabolic process;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0045766//positive regulation of angiogenesis;GO:0046677//response to antibiotic;GO:0051216//cartilage development;GO:0045927//positive regulation of growth;GO:0044281//small molecule metabolic process;GO:0000302//response to reactive oxygen species;GO:0010634//positive regulation of epithelial cell migration;GO:0071347//cellular response to interleukin-1;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0030207//chondroitin sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006954//inflammatory response;GO:0030212//hyaluronan metabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0030214//hyaluronan catabolic process;GO:0045785//positive regulation of cell adhesion;GO:0071467//cellular response to pH;GO:0030203//glycosaminoglycan metabolic process,GO:0001618//virus receptor activity;GO:0004415//hyalurononglucosaminidase activity;GO:0050501//hyaluronan synthase activity;GO:0008134//transcription factor binding,"K01197//Lysosome;Arginine and proline metabolism;Glycosaminoglycan degradation;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
3375,0,0,0,0,0,13,0,0,0,0,0,0,IAPP;islet amyloid polypeptide,GO:0043025//neuronal cell body;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0045779//negative regulation of bone resorption;GO:0007267//cell-cell signaling;GO:0019233//sensory perception of pain;GO:0031018//endocrine pancreas development;GO:0045596//negative regulation of cell differentiation;GO:0006915//apoptotic process;GO:0042755//eating behavior,GO:0005102//receptor binding;GO:0005179//hormone activity;GO:0042802//identical protein binding,K08039//Maturity onset diabetes of the young
3376,0,32,40,30,102,15,13,0,16,0,0,0,IARS;isoleucyl-tRNA synthetase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression;GO:0006450//regulation of translational fidelity;GO:0006428//isoleucyl-tRNA aminoacylation;GO:0001649//osteoblast differentiation,GO:0002161//aminoacyl-tRNA editing activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004822//isoleucine-tRNA ligase activity,K01870//Aminoacyl-tRNA biosynthesis;Flagellar assembly
337867,0,72,25,19,99,0,14,620,75,0,26,0,UBAC2;UBA domain containing 2,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0070972//protein localization to endoplasmic reticulum,-,-
337875,0,0,0,0,0,0,0,0,31,0,10,0,"HIST2H2BA;histone cluster 2, H2ba (pseudogene)",-,-,-,K11252//Alcoholism;Systemic lupus erythematosus
337876,0,0,0,0,0,0,0,0,8,0,0,12,CHSY3;chondroitin sulfate synthase 3,GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,K13499//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways
337880,0,0,0,0,0,0,0,31,0,0,0,0,KRTAP11-1;keratin associated protein 11-1,GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
337960,0,0,0,0,0,0,0,51,0,0,0,0,KRTAP13-3;keratin associated protein 13-3,GO:0005882//intermediate filament,-,-,-
337966,0,0,0,0,0,4,0,0,12,0,0,0,KRTAP6-1;keratin associated protein 6-1,GO:0005882//intermediate filament;GO:0005829//cytosol,-,-,-
337970,0,0,0,0,0,0,0,0,45,0,0,0,KRTAP19-3;keratin associated protein 19-3,GO:0005882//intermediate filament,-,-,-
337971,0,0,0,0,0,1,17,0,0,0,0,0,KRTAP19-4;keratin associated protein 19-4,GO:0005882//intermediate filament,-,-,-
338,39,0,0,0,0,23,33,0,93,0,44,0,APOB;apolipoprotein B,GO:0005737//cytoplasm;GO:0071682//endocytic vesicle lumen;GO:0034360//chylomicron remnant;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0010008//endosome membrane;GO:0005788//endoplasmic reticulum lumen;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0031904//endosome lumen;GO:0042627//chylomicron;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0034363//intermediate-density lipoprotein particle;GO:0034359//mature chylomicron;GO:0005789//endoplasmic reticulum membrane;GO:0034362//low-density lipoprotein particle;GO:0015629//actin cytoskeleton;GO:0034361//very-low-density lipoprotein particle;GO:0005829//cytosol,"GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0034379//very-low-density lipoprotein particle assembly;GO:0042159//lipoprotein catabolic process;GO:0033344//cholesterol efflux;GO:0010269//response to selenium ion;GO:0009615//response to virus;GO:0071379//cellular response to prostaglandin stimulus;GO:0030301//cholesterol transport;GO:0048844//artery morphogenesis;GO:0071356//cellular response to tumor necrosis factor;GO:0009791//post-embryonic development;GO:0007596//blood coagulation;GO:0042632//cholesterol homeostasis;GO:0045540//regulation of cholesterol biosynthetic process;GO:0006642//triglyceride mobilization;GO:0007283//spermatogenesis;GO:0010886//positive regulation of cholesterol storage;GO:0001701//in utero embryonic development;GO:0001523//retinoid metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0044281//small molecule metabolic process;GO:0010884//positive regulation of lipid storage;GO:0042953//lipoprotein transport;GO:0007603//phototransduction, visible light;GO:0032496//response to lipopolysaccharide;GO:0030317//sperm motility;GO:0008203//cholesterol metabolic process;GO:0019433//triglyceride catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0042157//lipoprotein metabolic process;GO:0050900//leukocyte migration;GO:0006898//receptor-mediated endocytosis;GO:0009743//response to carbohydrate;GO:0007399//nervous system development;GO:0009566//fertilization;GO:0034383//low-density lipoprotein particle clearance",GO:0005543//phospholipid binding;GO:0008201//heparin binding;GO:0035473//lipase binding;GO:0005515//protein binding;GO:0017127//cholesterol transporter activity;GO:0050750//low-density lipoprotein particle receptor binding,K14462//Fat digestion and absorption;Vitamin digestion and absorption
338069,0,15,0,0,0,0,0,0,21,0,0,0,ST7-OT4;ST7 overlapping transcript 4,-,-,-,-
338094,0,60,0,14,74,14,0,0,0,0,0,290,"FAM151A;family with sequence similarity 151, member A",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
3381,0,0,0,0,0,0,0,0,35,0,0,0,IBSP;integrin-binding sialoprotein,GO:0031988//membrane-bounded vesicle;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005576//extracellular region,GO:0001649//osteoblast differentiation;GO:0030198//extracellular matrix organization;GO:0031214//biomineral tissue development;GO:0007155//cell adhesion;GO:0071363//cellular response to growth factor stimulus,-,K06253//Focal adhesion;ECM-receptor interaction
3382,0,192,109,147,248,0,0,494,50,0,32,1,"ICA1;islet cell autoantigen 1, 69kDa",GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030667//secretory granule membrane;GO:0005737//cytoplasm;GO:0030658//transport vesicle membrane,GO:0006836//neurotransmitter transport,GO:0019904//protein domain specific binding,-
338321,13,1,0,0,0,0,0,32,1,0,0,0,"NLRP9;NLR family, pyrin domain containing 9",GO:0005737//cytoplasm,-,GO:0005524//ATP binding,K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
338322,0,0,0,0,0,0,7,0,0,0,1,0,"NLRP10;NLR family, pyrin domain containing 10",GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane,GO:2000778//positive regulation of interleukin-6 secretion;GO:2000484//positive regulation of interleukin-8 secretion;GO:0050832//defense response to fungus;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0035397//helper T cell enhancement of adaptive immune response;GO:0050829//defense response to Gram-negative bacterium;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0036336//dendritic cell migration;GO:0045087//innate immune response,GO:0005524//ATP binding,K12800//Influenza A;NOD-like receptor signaling pathway;Pertussis
338323,0,0,0,0,0,0,26,0,38,0,0,0,"NLRP14;NLR family, pyrin domain containing 14",-,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0005524//ATP binding,K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
338324,87,0,0,2,0,25,0,0,30,0,0,0,S100A7A;S100 calcium binding protein A7A,GO:0005737//cytoplasm,-,GO:0005509//calcium ion binding,-
338339,0,0,0,0,0,0,0,0,16,0,6,0,"CLEC4D;C-type lectin domain family 4, member D",GO:0016021//integral component of membrane,GO:0045087//innate immune response,GO:0030246//carbohydrate binding,-
3384,0,0,0,6,0,0,0,0,8,0,0,0,ICAM2;intercellular adhesion molecule 2,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0001931//uropod,GO:0030198//extracellular matrix organization;GO:0050776//regulation of immune response;GO:0016337//single organismal cell-cell adhesion,GO:0005178//integrin binding,K06523//Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity
338436,0,0,0,0,0,12,0,0,44,0,0,0,BLACE;B-cell acute lymphoblastic leukemia expressed,-,-,-,-
338440,0,0,0,0,11,0,0,149,46,1,0,0,ANO9;anoctamin 9,GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006821//chloride transport;GO:0055085//transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport,GO:0017128//phospholipid scramblase activity;GO:0005229//intracellular calcium activated chloride channel activity,-
338442,0,0,0,0,0,0,0,0,16,0,28,0,HCAR2;hydroxycarboxylic acid receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001781//neutrophil apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0033031//positive regulation of neutrophil apoptotic process;GO:0050995//negative regulation of lipid catabolic process;GO:0070165//positive regulation of adiponectin secretion,GO:0070553//nicotinic acid receptor activity,-
3385,104,14,90,85,92,0,0,116,28,0,48,60,ICAM3;intercellular adhesion molecule 3,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030198//extracellular matrix organization;GO:0050776//regulation of immune response;GO:0016337//single organismal cell-cell adhesion,GO:0005515//protein binding;GO:0005178//integrin binding;GO:0005102//receptor binding,K06486//Cell adhesion molecules (CAMs)
338557,64,0,0,0,0,0,0,0,0,0,8,0,FFAR4;free fatty acid receptor 4,GO:0016021//integral component of membrane;GO:0030139//endocytic vesicle;GO:0005886//plasma membrane,GO:0046879//hormone secretion;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0010827//regulation of glucose transport;GO:0050710//negative regulation of cytokine secretion;GO:0043066//negative regulation of apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0008527//taste receptor activity;GO:0005504//fatty acid binding,-
338567,93,0,0,0,0,12,0,45,0,0,3,1,"KCNK18;potassium channel, subfamily K, member 18",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006813//potassium ion transport;GO:0071435//potassium ion export;GO:0071467//cellular response to pH;GO:0007268//synaptic transmission,GO:0015271//outward rectifier potassium channel activity;GO:0015269//calcium-activated potassium channel activity;GO:0005267//potassium channel activity,K04920//Gastric acid secretion
338588,0,0,0,0,0,5,0,0,0,0,0,0,LINC00705;long intergenic non-protein coding RNA 705,-,-,-,-
338596,0,0,0,0,0,0,0,0,10,0,51,0,"ST8SIA6;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6",GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane,GO:0097503//sialylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0009247//glycolipid biosynthetic process;GO:0009311//oligosaccharide metabolic process;GO:0006493//protein O-linked glycosylation;GO:0001574//ganglioside biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0009100//glycoprotein metabolic process;GO:0016051//carbohydrate biosynthetic process,GO:0008373//sialyltransferase activity,-
338599,0,0,0,0,0,0,0,0,25,0,0,0,DUPD1;dual specificity phosphatase and pro isomerase domain containing 1,GO:0005737//cytoplasm,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
338645,190,0,0,8,7,39,0,139,3,0,0,0,LUZP2;leucine zipper protein 2,GO:0005576//extracellular region,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
338651,18,0,0,0,0,14,0,0,14,0,0,0,KRTAP5-AS1;KRTAP5-1/KRTAP5-2 antisense RNA 1,-,-,-,-
338657,1,415,589,682,591,0,17,17,5,0,186,0,CCDC84;coiled-coil domain containing 84,-,-,-,-
338661,0,0,0,0,0,0,12,0,21,0,0,0,TMEM225;transmembrane protein 225,GO:0016021//integral component of membrane,GO:0010923//negative regulation of phosphatase activity,-,-
338675,0,0,0,0,0,0,7,0,0,0,0,0,"OR5AP2;olfactory receptor, family 5, subfamily AP, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
338692,96,0,0,0,0,0,0,0,4,0,0,289,"ANKRD13D;ankyrin repeat domain 13 family, member D",GO:0005886//plasma membrane;GO:0005770//late endosome,-,-,-
338707,0,0,0,0,0,5,23,0,70,0,6,0,"B4GALNT4;beta-1,4-N-acetyl-galactosaminyl transferase 4",GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0008376//acetylgalactosaminyltransferase activity;GO:0033842//N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity,-
338755,0,0,0,0,0,0,0,0,25,0,0,0,"OR2AG2;olfactory receptor, family 2, subfamily AG, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
338761,0,0,0,0,0,13,0,0,12,0,0,0,"C1QL4;complement component 1, q subcomponent-like 4",GO:0005581//collagen trimer;GO:0005576//extracellular region,-,-,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
338773,0,0,0,0,0,0,0,0,0,3,0,0,TMEM119;transmembrane protein 119,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0001649//osteoblast differentiation,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
338785,64,0,0,0,0,23,12,0,27,0,0,0,KRT79;keratin 79,GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,-,GO:0019899//enzyme binding;GO:0005198//structural molecule activity,-
338797,0,0,0,0,0,14,0,0,0,0,0,0,LOC338797;uncharacterized LOC338797,-,-,-,K13911//Salivary secretion
338809,0,0,0,0,0,0,85,0,21,0,0,0,C12orf74;chromosome 12 open reading frame 74,-,-,-,-
338811,0,0,0,0,0,0,0,1,3,0,9,524,"FAM19A2;family with sequence similarity 19 (chemokine (C-C motif)-like), member A2",GO:0005737//cytoplasm,-,-,-
338821,105,0,0,0,0,12,0,0,0,1,0,0,"SLCO1B7;solute carrier organic anion transporter family, member 1B7 (non-functional)",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006810//transport,GO:0005215//transporter activity,K05043//Bile secretion
338872,0,0,2,3,5,0,0,0,1,0,0,0,C1QTNF9;C1q and tumor necrosis factor related protein 9,GO:0005581//collagen trimer;GO:0005576//extracellular region,-,GO:0005179//hormone activity,K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus
338917,0,0,0,0,0,0,0,41,52,115,18,0,VSX2;visual system homeobox 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0060040//retinal bipolar neuron differentiation",GO:0043565//sequence-specific DNA binding,-
338949,30,0,0,0,0,14,0,0,0,0,0,0,TMEM202;transmembrane protein 202,GO:0016021//integral component of membrane,-,-,-
339,0,0,0,0,0,7,0,0,0,0,0,0,"APOBEC1;apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1",GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0042953//lipoprotein transport;GO:0009972//cytidine deamination;GO:0042493//response to drug;GO:0042158//lipoprotein biosynthetic process;GO:0006629//lipid metabolic process;GO:0010467//gene expression;GO:0045471//response to ethanol;GO:0006397//mRNA processing;GO:0090310//negative regulation of methylation-dependent chromatin silencing;GO:0010332//response to gamma radiation;GO:0032869//cellular response to insulin stimulus;GO:0016554//cytidine to uridine editing;GO:0080111//DNA demethylation;GO:0016556//mRNA modification;GO:0006970//response to osmotic stress;GO:0010043//response to zinc ion;GO:0042127//regulation of cell proliferation;GO:0006396//RNA processing;GO:0051607//defense response to virus;GO:0048255//mRNA stabilization;GO:0051592//response to calcium ion,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004126//cytidine deaminase activity;GO:0017091//AU-rich element binding;GO:0003723//RNA binding,K01500//Microbial metabolism in diverse environments;Atrazine degradation
339005,0,0,0,0,0,0,18,0,4,0,0,0,"WHAMMP3;WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3",-,-,-,-
339044,1,1,0,0,0,1,3,14,10,58,1,1,PKD1P1;polycystic kidney disease 1 (autosomal dominant) pseudogene 1,-,-,-,-
339059,42,0,0,0,0,0,0,0,11,0,0,236,LOC339059;uncharacterized LOC339059,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
339105,0,23,0,0,0,0,62,0,5,0,0,0,"PRSS53;protease, serine, 53",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
339122,0,0,0,0,0,4,0,0,41,0,0,0,"RAB43;RAB43, member RAS oncogene family",GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus,"GO:0035526//retrograde transport, plasma membrane to Golgi;GO:0019068//virion assembly;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0090382//phagosome maturation",GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding,-
339123,3,2719,1348,1739,2692,0,125,4037,617,399,6214,378,JMJD8;jumonji domain containing 8,GO:0070062//extracellular vesicular exosome,-,-,K09561//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis
339145,0,0,0,0,7,0,0,0,7,0,0,0,"FAM92B;family with sequence similarity 92, member B",-,-,-,K02258//Metabolic pathways;Oxidative phosphorylation
339168,0,0,0,0,0,5,0,0,0,0,1,0,TMEM95;transmembrane protein 95,GO:0016021//integral component of membrane,-,-,-
339175,0,0,0,10,1,0,0,0,12,0,4,0,METTL2A;methyltransferase like 2A,-,GO:0030488//tRNA methylation,GO:0016427//tRNA (cytosine) methyltransferase activity,K00599//Polycyclic aromatic hydrocarbon degradation;Lipopolysaccharide biosynthesis;Tyrosine metabolism;Microbial metabolism in diverse environments;Histidine metabolism;Metabolic pathways
339184,0,0,0,0,0,0,13,57,0,0,0,225,"CCDC144NL;coiled-coil domain containing 144 family, N-terminal like",-,-,-,-
339201,0,0,0,0,0,8,0,0,6,0,5,0,ASB16-AS1;ASB16 antisense RNA 1,-,-,-,K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Biotin metabolism;Arginine and proline metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
339210,0,0,0,8,0,0,0,0,32,0,0,0,C17orf67;chromosome 17 open reading frame 67,GO:0005576//extracellular region,-,-,-
339221,0,0,0,0,0,0,0,0,5,0,0,0,ENPP7;ectonucleotide pyrophosphatase/phosphodiesterase 7,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005902//microvillus,GO:0006665//sphingolipid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0008156//negative regulation of DNA replication;GO:0044281//small molecule metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006684//sphingomyelin metabolic process,GO:0004767//sphingomyelin phosphodiesterase activity,K12354//Metabolic pathways;Sphingolipid metabolism
339229,0,0,0,0,0,0,0,0,0,0,6,0,OXLD1;oxidoreductase-like domain containing 1,GO:0005739//mitochondrion,-,-,-
339230,0,0,0,5,1,0,45,42,16,0,0,0,CCDC137;coiled-coil domain containing 137,-,-,GO:0044822//poly(A) RNA binding,K12182//Endocytosis;Phagosome
339231,0,0,0,1,5,0,12,0,0,0,0,0,ARL16;ADP-ribosylation factor-like 16,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,K11447//Transcriptional misregulation in cancer
339240,48,0,0,0,0,5,18,0,16,0,0,0,KRT17P5;keratin 17 pseudogene 5,GO:0005576//extracellular region,-,-,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
339263,0,0,0,0,0,25,0,0,29,0,0,0,C17orf51;chromosome 17 open reading frame 51,-,-,-,-
339287,0,68,1,42,102,0,10,47,38,0,8,0,MSL1;male-specific lethal 1 homolog (Drosophila),GO:0072487//MSL complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0043984//histone H4-K16 acetylation;GO:0006325//chromatin organization,-,-
339291,55,0,0,0,0,0,24,0,12,0,0,0,LRRC30;leucine rich repeat containing 30,-,-,-,K10130//p53 signaling pathway;NF-kappa B signaling pathway
339302,0,0,0,0,0,0,0,0,22,0,0,0,CPLX4;complexin 4,GO:0016020//membrane;GO:0045202//synapse;GO:0030054//cell junction,GO:0006836//neurotransmitter transport;GO:0006887//exocytosis;GO:0046928//regulation of neurotransmitter secretion,GO:0019905//syntaxin binding,K15295//Synaptic vesicle cycle
339318,134,0,0,17,33,0,0,0,0,0,15,0,ZNF181;zinc finger protein 181,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
339324,0,3,1,44,144,0,55,0,55,0,0,0,ZNF260;zinc finger protein 260,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
339344,0,0,0,0,0,0,9,0,0,0,11,0,"MYPOP;Myb-related transcription factor, partner of profilin",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0042803//protein homodimerization activity,-
339345,0,0,0,0,0,27,0,0,15,0,0,0,NANOS2;nanos homolog 2 (Drosophila),GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body,GO:0006402//mRNA catabolic process;GO:0045835//negative regulation of meiosis;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006417//regulation of translation;GO:0030718//germ-line stem cell maintenance,GO:0008270//zinc ion binding;GO:0003729//mRNA binding,-
339366,1,0,0,0,9,1,39,0,45,0,3,0,ADAMTSL5;ADAMTS-like 5,GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0001527//microfibril;GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008201//heparin binding,-
339390,0,0,0,0,0,14,13,0,47,0,0,0,"CLEC4G;C-type lectin domain family 4, member G",GO:0016021//integral component of membrane,-,GO:0005515//protein binding;GO:0030246//carbohydrate binding,-
339398,0,0,0,0,0,0,0,0,8,0,13,0,LINGO4;leucine rich repeat and Ig domain containing 4,GO:0016021//integral component of membrane,-,-,K07523//Axon guidance
3394,0,0,0,0,19,0,0,1,55,0,0,0,IRF8;interferon regulatory factor 8,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0006366//transcription from RNA polymerase II promoter;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0006955//immune response;GO:0032735//positive regulation of interleukin-12 production;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0042742//defense response to bacterium;GO:0006909//phagocytosis;GO:0060337//type I interferon signaling pathway;GO:0044130//negative regulation of growth of symbiont in host;GO:0032729//positive regulation of interferon-gamma production;GO:0071222//cellular response to lipopolysaccharide;GO:0042832//defense response to protozoan;GO:0030099//myeloid cell differentiation,GO:0005515//protein binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0000975//regulatory region DNA binding,K10155//Pertussis
339400,0,0,0,0,0,14,0,0,0,0,0,0,FLG-AS1;FLG antisense RNA 1,-,-,-,-
339403,0,0,0,0,0,0,0,0,16,0,0,0,RXFP4;relaxin/insulin-like family peptide receptor 4,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0038166//angiotensin-activated signaling pathway,GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding,-
339416,0,0,1,0,0,0,0,0,11,0,2,0,ANKRD45;ankyrin repeat domain 45,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
339448,0,0,0,5,14,17,0,0,0,0,0,0,C1orf174;chromosome 1 open reading frame 174,GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
339451,0,0,0,0,0,14,0,0,23,0,16,0,KLHL17;kelch-like family member 17,GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0005615//extracellular space;GO:0015629//actin cytoskeleton;GO:0045211//postsynaptic membrane;GO:0032839//dendrite cytoplasm;GO:0030054//cell junction,GO:0016567//protein ubiquitination;GO:0007420//brain development;GO:0030036//actin cytoskeleton organization,GO:0031208//POZ domain binding;GO:0032947//protein complex scaffold;GO:0051015//actin filament binding,-
339456,0,0,8,0,0,0,0,0,0,0,5,0,TMEM52;transmembrane protein 52,GO:0016021//integral component of membrane,-,-,-
339479,0,0,0,0,2,12,14,0,9,0,0,0,BRINP3;bone morphogenetic protein/retinoic acid inducible neural-specific 3,GO:0043025//neuronal cell body;GO:0030425//dendrite;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum,GO:0045930//negative regulation of mitotic cell cycle;GO:0071300//cellular response to retinoic acid;GO:0007050//cell cycle arrest;GO:0045666//positive regulation of neuron differentiation,-,-
339483,0,0,0,16,17,0,18,0,14,0,0,0,"MTMR9LP;myotubularin related protein 9-like, pseudogene",-,-,-,K01112//Fructose and mannose metabolism
339487,0,0,0,1,56,38,0,0,0,0,6,0,ZBTB8OS;zinc finger and BTB domain containing 8 opposite strand,GO:0070062//extracellular vesicular exosome;GO:0072669//tRNA-splicing ligase complex,"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation",-,-
339500,0,38,0,20,3,0,0,0,43,0,0,0,ZNF678;zinc finger protein 678,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
339501,51,0,0,0,0,0,0,0,16,0,0,462,"PRSS38;protease, serine, 38",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
339512,0,0,0,0,0,23,0,0,24,0,0,0,C1orf110;chromosome 1 open reading frame 110,-,-,-,-
339539,0,0,0,0,0,0,0,0,26,0,21,0,LOC339539;uncharacterized LOC339539,-,-,-,-
339541,113,0,0,0,0,0,0,49,0,0,0,0,C1orf228;chromosome 1 open reading frame 228,-,-,-,-
339559,0,0,0,0,0,12,0,0,72,0,0,0,ZFP69;ZFP69 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
3396,0,0,0,0,9,20,0,0,15,0,2,0,ICT1;immature colon carcinoma transcript 1,GO:0005762//mitochondrial large ribosomal subunit;GO:0005739//mitochondrion,GO:0070126//mitochondrial translational termination,"GO:0016150//translation release factor activity, codon nonspecific;GO:0004045//aminoacyl-tRNA hydrolase activity",-
339665,6,0,0,0,0,34,18,1,14,0,7,0,"SLC35E4;solute carrier family 35, member E4",GO:0016021//integral component of membrane,-,-,-
339674,0,0,0,0,0,0,0,0,30,0,0,0,LINC00634;long intergenic non-protein coding RNA 634,-,-,-,-
3397,0,1,1,25,116,0,0,0,0,0,0,0,"ID1;inhibitor of DNA binding 1, dominant negative helix-loop-helix protein",GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0007507//heart development;GO:0046677//response to antibiotic;GO:0001525//angiogenesis;GO:0060425//lung morphogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032963//collagen metabolic process;GO:0043408//regulation of MAPK cascade;GO:0030509//BMP signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-templated;GO:0001886//endothelial cell morphogenesis;GO:0060426//lung vasculature development;GO:0043534//blood vessel endothelial cell migration;GO:0045765//regulation of angiogenesis;GO:0048514//blood vessel morphogenesis;GO:0043392//negative regulation of DNA binding;GO:0048511//rhythmic process;GO:0010621//negative regulation of transcription by transcription factor localization;GO:0031648//protein destabilization;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046983//protein dimerization activity,K04680//Transcriptional misregulation in cancer;TGF-beta signaling pathway
339745,0,91,0,80,298,0,7,0,46,0,0,0,SPOPL;speckle-type POZ protein-like,GO:0005634//nucleus;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0031397//negative regulation of protein ubiquitination;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,-,-
339751,92,106,45,317,279,0,1,29,48,0,266,0,MLK7-AS1;MLK7 antisense RNA 1,-,-,-,K04424//MAPK signaling pathway;Tight junction
339761,0,0,0,0,0,29,0,36,25,0,6,0,"CYP27C1;cytochrome P450, family 27, subfamily C, polypeptide 1",GO:0016020//membrane,GO:0055114//oxidation-reduction process,"GO:0004497//monooxygenase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",K07438//Tuberculosis;Metabolic pathways;Steroid biosynthesis;K00488//PPAR signaling pathway;Metabolic pathways;Primary bile acid biosynthesis
339766,0,0,26,0,6,95,34,0,18,0,0,0,MROH2A;maestro heat-like repeat family member 2A,-,-,-,-
339768,23,0,0,0,0,0,0,82,47,105,0,0,ESPNL;espin-like,-,-,-,-
339778,0,0,0,0,0,0,0,0,7,0,0,0,C2orf70;chromosome 2 open reading frame 70,GO:0005634//nucleus,-,-,-
339779,0,0,0,0,0,0,48,7,16,0,0,0,PRR30;proline rich 30,-,-,-,-
3398,0,0,0,1,59,13,0,0,0,0,0,3,"ID2;inhibitor of DNA binding 2, dominant negative helix-loop-helix protein",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0043234//protein complex;GO:0000785//chromatin;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0032922//circadian regulation of gene expression;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0045665//negative regulation of neuron differentiation;GO:0045777//positive regulation of blood pressure;GO:0019216//regulation of lipid metabolic process;GO:0060612//adipose tissue development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0090398//cellular senescence;GO:0061030//epithelial cell differentiation involved in mammary gland alveolus development;GO:0001656//metanephros development;GO:0043353//enucleate erythrocyte differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0045651//positive regulation of macrophage differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021772//olfactory bulb development;GO:0048711//positive regulation of astrocyte differentiation;GO:0007275//multicellular organismal development;GO:0043153//entrainment of circadian clock by photoperiod;GO:0048663//neuron fate commitment;GO:0043392//negative regulation of DNA binding;GO:0003149//membranous septum morphogenesis;GO:0014003//oligodendrocyte development;GO:0001779//natural killer cell differentiation;GO:0006351//transcription, DNA-templated;GO:0060749//mammary gland alveolus development;GO:0045648//positive regulation of erythrocyte differentiation;GO:0033598//mammary gland epithelial cell proliferation;GO:0010628//positive regulation of gene expression;GO:0071285//cellular response to lithium ion;GO:0048469//cell maturation;GO:0048541//Peyer's patch development;GO:0010629//negative regulation of gene expression;GO:0071158//positive regulation of cell cycle arrest;GO:0071931//positive regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0003166//bundle of His development;GO:0042752//regulation of circadian rhythm;GO:0061031//endodermal digestive tract morphogenesis;GO:0045787//positive regulation of cell cycle;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0045475//locomotor rhythm;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045600//positive regulation of fat cell differentiation;GO:0045578//negative regulation of B cell differentiation",GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0046983//protein dimerization activity,K04680//Transcriptional misregulation in cancer;TGF-beta signaling pathway
339804,0,0,0,16,0,0,0,0,0,0,12,0,C2orf74;chromosome 2 open reading frame 74,GO:0016021//integral component of membrane,-,-,-
339822,0,0,0,0,0,10,0,0,0,0,0,0,LINC01115;long intergenic non-protein coding RNA 1115,-,-,-,-
339829,0,0,0,0,14,0,23,0,30,0,7,0,CCDC39;coiled-coil domain containing 39,GO:0005930//axoneme;GO:0005856//cytoskeleton,GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0035469//determination of pancreatic left/right asymmetry;GO:0060285//cilium-dependent cell motility;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry;GO:0001947//heart looping;GO:0070286//axonemal dynein complex assembly;GO:0030324//lung development,-,K12478//Tuberculosis;Endocytosis;Phagosome
339834,0,0,0,0,0,0,0,0,41,0,16,0,CCDC36;coiled-coil domain containing 36,-,-,-,K01557//Tyrosine metabolism;Metabolic pathways
339855,0,0,51,0,0,0,8,0,17,124,0,0,KY;kyphoscoliosis peptidase,GO:0030018//Z disc;GO:0005856//cytoskeleton,GO:0006508//proteolysis;GO:0007528//neuromuscular junction development;GO:0007517//muscle organ development,GO:0008233//peptidase activity,-
339896,162,0,0,0,0,0,0,0,44,92,0,0,GADL1;glutamate decarboxylase-like 1,-,GO:0019752//carboxylic acid metabolic process,GO:0030170//pyridoxal phosphate binding;GO:0004782//sulfinoalanine decarboxylase activity;GO:0004068//aspartate 1-decarboxylase activity,K01594//Metabolic pathways;Taurine and hypotaurine metabolism
339906,0,0,0,0,0,0,0,0,50,0,12,0,"PRSS42;protease, serine, 42",GO:0005576//extracellular region;GO:0046658//anchored component of plasma membrane;GO:0005737//cytoplasm,GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0007281//germ cell development,GO:0004252//serine-type endopeptidase activity,-
339965,0,0,0,0,0,0,14,0,31,0,10,0,CCDC158;coiled-coil domain containing 158,-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K12478//Tuberculosis;Phagosome;Endocytosis
339967,0,0,0,0,0,0,0,0,6,0,0,0,"TMPRSS11A;transmembrane protease, serine 11A",GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis;GO:0007049//cell cycle,GO:0004252//serine-type endopeptidase activity,-
339975,0,0,0,0,10,0,0,0,6,0,0,0,LOC339975;uncharacterized LOC339975,-,-,-,-
339976,0,33,0,0,0,0,0,0,1,0,0,0,TRIML1;tripartite motif family-like 1,-,GO:0016567//protein ubiquitination;GO:0007275//multicellular organismal development,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
339977,98,0,0,0,0,13,0,0,5,0,0,0,LRRC66;leucine rich repeat containing 66,GO:0016021//integral component of membrane,-,-,-
339983,0,0,0,0,0,0,0,0,60,0,0,0,"NAT8L;N-acetyltransferase 8-like (GCN5-related, putative)",GO:0005737//cytoplasm;GO:0030867//rough endoplasmic reticulum membrane;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission,GO:0017188//aspartate N-acetyltransferase activity,K01330//Pertussis;Complement and coagulation cascades;Systemic lupus erythematosus;Staphylococcus aureus infection;Phagosome;K13911//Salivary secretion
34,5,38,0,33,23,14,0,0,29,0,0,0,"ACADM;acyl-CoA dehydrogenase, C-4 to C-12 straight chain",GO:0005739//mitochondrion;GO:0030424//axon;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005759//mitochondrial matrix,"GO:0045329//carnitine biosynthetic process;GO:0055114//oxidation-reduction process;GO:0055007//cardiac muscle cell differentiation;GO:0051793//medium-chain fatty acid catabolic process;GO:0019254//carnitine metabolic process, CoA-linked;GO:0009791//post-embryonic development;GO:0042594//response to starvation;GO:0009409//response to cold;GO:0006635//fatty acid beta-oxidation;GO:0051791//medium-chain fatty acid metabolic process;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0044255//cellular lipid metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0001889//liver development",GO:0042802//identical protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0070991//medium-chain-acyl-CoA dehydrogenase activity;GO:0003995//acyl-CoA dehydrogenase activity,"K00249//Fatty acid metabolism;Biosynthesis of unsaturated fatty acids;Propanoate metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Biosynthesis of secondary metabolites;Peroxisome;alpha-Linolenic acid metabolism;PPAR signaling pathway"
3400,0,50,1,34,186,0,0,56,0,0,12,0,"ID4;inhibitor of DNA binding 4, dominant negative helix-loop-helix protein",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045665//negative regulation of neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045599//negative regulation of fat cell differentiation;GO:0021895//cerebral cortex neuron differentiation;GO:0008284//positive regulation of cell proliferation;GO:0021766//hippocampus development;GO:0045669//positive regulation of osteoblast differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0034613//cellular protein localization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048712//negative regulation of astrocyte differentiation;GO:0007405//neuroblast proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0022010//central nervous system myelination;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0046983//protein dimerization activity;GO:0003714//transcription corepressor activity,K04680//TGF-beta signaling pathway;Transcriptional misregulation in cancer
340017,0,0,0,0,0,0,0,2,7,0,0,0,LOC340017;uncharacterized LOC340017,-,-,-,-
340024,66,0,0,0,3,51,0,107,97,0,0,0,"SLC6A19;solute carrier family 6 (neutral amino acid transporter), member 19",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane,GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0015804//neutral amino acid transport;GO:0007584//response to nutrient;GO:0006865//amino acid transport,GO:0005328//neurotransmitter:sodium symporter activity;GO:0015175//neutral amino acid transmembrane transporter activity,K05334//Protein digestion and absorption;Mineral absorption
340061,0,0,0,0,0,0,24,0,0,0,0,0,TMEM173;transmembrane protein 173,GO:0005777//peroxisome;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane,"GO:0042993//positive regulation of transcription factor import into nucleus;GO:0002218//activation of innate immune response;GO:0035458//cellular response to interferon-beta;GO:0071360//cellular response to exogenous dsRNA;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0002230//positive regulation of defense response to virus by host;GO:0032092//positive regulation of protein binding;GO:0006915//apoptotic process;GO:0032608//interferon-beta production",GO:0061507//cyclic-GMP-AMP binding;GO:0035438//cyclic-di-GMP binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008134//transcription factor binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding,K12654//Cytosolic DNA-sensing pathway;RIG-I-like receptor signaling pathway
340069,0,0,0,0,0,0,0,60,22,0,0,0,"FAM170A;family with sequence similarity 170, member A",GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
340075,0,0,1,0,0,0,12,0,0,125,0,0,"ARSI;arylsulfatase family, member I",GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process,GO:0004065//arylsulfatase activity;GO:0046872//metal ion binding,-
340120,173,0,0,0,0,0,0,0,7,0,0,361,ANKRD34B;ankyrin repeat domain 34B,GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
340146,0,0,0,0,0,0,0,0,24,0,11,0,"SLC35D3;solute carrier family 35, member D3",GO:0016021//integral component of membrane,GO:0008643//carbohydrate transport,-,-
340152,0,0,0,0,0,3,0,0,34,0,20,0,ZC3H12D;zinc finger CCCH-type containing 12D,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0030308//negative regulation of cell growth,GO:0046872//metal ion binding;GO:0004519//endonuclease activity,K11447//Transcriptional misregulation in cancer
340156,50,0,0,0,0,32,15,0,32,0,2,0,"MYLK4;myosin light chain kinase family, member 4",GO:0070062//extracellular vesicular exosome,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
340168,0,0,0,0,0,15,0,0,6,0,0,0,DPPA5;developmental pluripotency associated 5,GO:0005737//cytoplasm,GO:0007275//multicellular organismal development,GO:0003723//RNA binding,-
340198,0,0,0,0,0,3,0,0,0,0,0,0,IFITM4P;interferon induced transmembrane protein 4 pseudogene,-,-,-,K06566//B cell receptor signaling pathway
340205,73,0,0,0,0,0,0,0,32,1,0,335,TREML1;triggering receptor expressed on myeloid cells-like 1,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0031091//platelet alpha granule;GO:0005886//plasma membrane,GO:0019722//calcium-mediated signaling;GO:0045087//innate immune response;GO:0030168//platelet activation,GO:0005515//protein binding,-
340206,0,0,0,0,0,0,0,0,11,0,0,0,"TREML3P;triggering receptor expressed on myeloid cells-like 3, pseudogene",-,-,-,K06742//Natural killer cell mediated cytotoxicity
340252,0,31,0,39,56,0,0,0,3,0,0,0,ZNF680;zinc finger protein 680,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
340267,0,0,0,0,0,0,30,0,100,0,0,0,"COL28A1;collagen, type XXVIII, alpha 1",GO:0005604//basement membrane;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005788//endoplasmic reticulum lumen,GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
340273,0,0,0,0,0,10,74,32,83,96,0,0,"ABCB5;ATP-binding cassette, sub-family B (MDR/TAP), member 5",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0006200//ATP catabolic process;GO:0002485//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent;GO:0002489//antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent;GO:0055085//transmembrane transport;GO:0042391//regulation of membrane potential;GO:0002591//positive regulation of antigen processing and presentation of peptide antigen via MHC class I;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0048058//compound eye corneal lens development","GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0015562//efflux transmembrane transporter activity",K05660//ABC transporters
340286,0,0,0,0,0,17,0,0,0,0,17,0,FAM183B;acyloxyacyl hydrolase (neutrophil),-,-,-,-
340307,0,0,4,5,17,0,0,1,0,0,5,0,"CTAGE6;CTAGE family, member 6",GO:0016021//integral component of membrane,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
340348,4,0,0,0,0,1,0,0,16,0,0,2,TSPAN33;tetraspanin 33,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097197//tetraspanin-enriched microdomain,GO:0051604//protein maturation;GO:0090002//establishment of protein localization to plasma membrane,GO:0019899//enzyme binding,-
340351,0,0,0,0,10,0,7,0,52,0,1,0,AGBL3;ATP/GTP binding protein-like 3,GO:0005829//cytosol,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,K14611//Vitamin digestion and absorption
340359,0,0,0,0,0,0,0,0,27,0,0,0,KLHL38;kelch-like family member 38,-,-,GO:0005515//protein binding,-
340371,70,1,0,0,31,40,0,90,55,0,0,341,NRBP2;nuclear receptor binding protein 2,GO:0005737//cytoplasm,GO:0030182//neuron differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0016242//negative regulation of macroautophagy;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0005524//ATP binding,-
340385,92,0,0,9,14,0,0,71,43,49,65,0,ZNF517;zinc finger protein 517,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
340390,78,1,25,12,0,0,74,62,70,144,9,0,KIAA1875;KIAA1875,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
340393,102,0,1,0,1,0,0,0,15,0,1,0,TMEM249;transmembrane protein 249,GO:0016021//integral component of membrane,-,-,-
340419,0,0,0,0,0,25,0,0,0,0,0,0,RSPO2;R-spondin 2,GO:0005576//extracellular region;GO:0009986//cell surface,GO:0060535//trachea cartilage morphogenesis;GO:0001649//osteoblast differentiation;GO:0060437//lung growth;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0016055//Wnt signaling pathway;GO:0035115//embryonic forelimb morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0030282//bone mineralization,GO:0005102//receptor binding;GO:0008201//heparin binding,-
340441,0,0,0,0,0,0,44,0,25,0,0,67,"POTEA;POTE ankyrin domain family, member A",-,-,-,-
340481,0,2,0,15,4,0,17,1,40,0,0,317,"ZDHHC21;zinc finger, DHHC-type containing 21",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0048733//sebaceous gland development;GO:0046209//nitric oxide metabolic process;GO:0044281//small molecule metabolic process;GO:0001942//hair follicle development;GO:0050999//regulation of nitric-oxide synthase activity;GO:0018345//protein palmitoylation;GO:0018230//peptidyl-L-cysteine S-palmitoylation,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding,K05766//Regulation of actin cytoskeleton
340485,0,0,10,3,1,23,3,0,23,76,14,16,ACER2;alkaline ceramidase 2,GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane;GO:0005794//Golgi apparatus,GO:0030148//sphingolipid biosynthetic process;GO:0006672//ceramide metabolic process;GO:0044281//small molecule metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032526//response to retinoic acid;GO:0090285//negative regulation of protein glycosylation in Golgi;GO:0001953//negative regulation of cell-matrix adhesion;GO:0046512//sphingosine biosynthetic process;GO:0035690//cellular response to drug;GO:0006665//sphingolipid metabolic process;GO:0010942//positive regulation of cell death;GO:0033629//negative regulation of cell adhesion mediated by integrin,GO:0017040//ceramidase activity;GO:0071633//dihydroceramidase activity,K01441//Sphingolipid metabolism;Metabolic pathways
340515,0,0,0,0,0,0,0,0,19,1,0,609,LOC340515;uncharacterized LOC340515,-,-,-,-
340526,0,0,0,0,0,25,19,0,4,0,5,0,RGAG4;retrotransposon gag domain containing 4,-,-,-,-
340527,0,0,0,0,0,13,32,0,47,0,10,0,NHSL2;NHS-like 2,-,-,-,-
340529,0,0,0,1,3,0,22,1,8,0,27,0,"PABPC1L2A;poly(A) binding protein, cytoplasmic 1-like 2A",-,-,-,K13126//RNA transport;mRNA surveillance pathway;RNA degradation
340533,95,0,1,5,86,9,0,0,58,0,1,0,KIAA2022;KIAA2022,GO:0043625//delta DNA polymerase complex;GO:0005634//nucleus,"GO:0043137//DNA replication, removal of RNA primer;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0019985//translesion synthesis;GO:0007346//regulation of mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006287//base-excision repair, gap-filling;GO:0045004//DNA replication proofreading;GO:0007399//nervous system development",GO:0003887//DNA-directed DNA polymerase activity;GO:0008408//3'-5' exonuclease activity,K02350//Metabolic pathways;Fanconi anemia pathway
340542,0,0,0,0,13,0,0,0,11,0,0,0,"BEX5;brain expressed, X-linked 5",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,-,-,K12465//Neurotrophin signaling pathway
340543,0,0,0,0,0,0,0,43,27,0,0,0,TCEAL5;transcription elongation factor A (SII)-like 5,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,K13749//Phototransduction
340547,0,0,0,0,0,10,9,0,70,0,4,141,VSIG1;V-set and immunoglobulin domain containing 1,GO:0016021//integral component of membrane,-,-,-
340554,0,0,0,2,0,0,0,1,69,214,0,0,ZC3H12B;zinc finger CCCH-type containing 12B,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0046872//metal ion binding;GO:0004519//endonuclease activity,K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
340562,0,155,151,215,134,0,1,93,0,157,241,0,SATL1;spermidine/spermine N1-acetyl transferase-like 1,-,GO:0008152//metabolic process,GO:0008080//N-acetyltransferase activity,K00657//ABC transporters;Metabolic pathways;Arginine and proline metabolism
340578,0,0,0,0,0,0,22,0,0,0,6,0,DCAF12L2;DDB1 and CUL4 associated factor 12-like 2,-,-,-,-
340591,0,0,0,0,1,0,0,0,0,0,0,0,CA5BP1;carbonic anhydrase VB pseudogene 1,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity,K01672//Collecting duct acid secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Nitrogen metabolism;Pancreatic secretion;Bile secretion
340595,0,0,0,0,0,7,0,0,0,0,23,0,"ZCCHC16;zinc finger, CCHC domain containing 16",-,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism
340596,103,0,0,0,0,0,0,0,18,0,0,0,LHFPL1;lipoma HMGIC fusion partner-like 1,GO:0016021//integral component of membrane,-,-,-
340602,0,0,0,0,7,0,0,0,22,0,0,0,CXorf67;chromosome X open reading frame 67,-,-,-,K13171//mRNA surveillance pathway;RNA transport
340654,0,0,0,0,5,0,0,0,32,52,7,0,"LIPM;lipase, family member M",GO:0005576//extracellular region,GO:0016042//lipid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds",K01052//Lysosome;Steroid biosynthesis
340665,0,0,0,0,0,0,19,0,0,14,0,0,"CYP26C1;cytochrome P450, family 26, subfamily C, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0048284//organelle fusion;GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0014032//neural crest cell development;GO:0007417//central nervous system development;GO:0034653//retinoic acid catabolic process;GO:0009952//anterior/posterior pattern specification;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0008401//retinoic acid 4-hydroxylase activity;GO:0020037//heme binding;GO:0001972//retinoic acid binding;GO:0005506//iron ion binding,K12665//Retinol metabolism
340706,0,15,10,0,14,12,3,44,50,0,0,0,VWA2;von Willebrand factor A domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005604//basement membrane,GO:0007161//calcium-independent cell-matrix adhesion;GO:0046626//regulation of insulin receptor signaling pathway;GO:0051260//protein homooligomerization,GO:0042802//identical protein binding,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
340719,0,70,42,129,124,0,0,0,58,0,210,0,NANOS1;nanos homolog 1 (Drosophila),GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0017148//negative regulation of translation;GO:0010631//epithelial cell migration;GO:0016477//cell migration,GO:0005515//protein binding;GO:0030371//translation repressor activity;GO:0008270//zinc ion binding;GO:0003723//RNA binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
340745,0,0,0,0,0,10,0,0,0,0,17,0,"LRIT2;leucine-rich repeat, immunoglobulin-like and transmembrane domains 2",GO:0016021//integral component of membrane,-,-,K06850//Axon guidance
340784,0,0,0,0,0,0,0,0,6,0,0,0,HMX3;H6 family homeobox 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0042472//inner ear morphogenesis;GO:0007566//embryo implantation;GO:0007420//brain development;GO:0050885//neuromuscular process controlling balance;GO:0006351//transcription, DNA-templated;GO:0060135//maternal process involved in female pregnancy",GO:0043565//sequence-specific DNA binding,-
340895,0,0,0,0,0,0,6,39,102,0,4,0,MALRD1;MAM and LDL receptor class A domain containing 1,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0042632//cholesterol homeostasis;GO:0070858//negative regulation of bile acid biosynthetic process,-,-
340900,0,0,0,0,0,0,31,0,0,1,0,0,EBLN1;endogenous Bornavirus-like nucleoprotein 1,-,-,-,-
340980,0,0,0,0,0,0,13,0,5,0,0,0,"OR52B6;olfactory receptor, family 52, subfamily B, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
340990,196,0,0,0,0,17,85,59,88,146,0,2,OTOG;otogelin,GO:0005578//proteinaceous extracellular matrix;GO:0016324//apical plasma membrane;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0008344//adult locomotory behavior;GO:0046373//L-arabinose metabolic process;GO:0007605//sensory perception of sound,GO:0005198//structural molecule activity;GO:0046556//alpha-L-arabinofuranosidase activity,K03900//Complement and coagulation cascades;Focal adhesion;ECM-receptor interaction
341,0,0,0,0,0,0,0,0,2,0,0,0,APOC1;apolipoprotein C-I,GO:0070062//extracellular vesicular exosome;GO:0034361//very-low-density lipoprotein particle;GO:0005783//endoplasmic reticulum;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron,GO:0050995//negative regulation of lipid catabolic process;GO:0034447//very-low-density lipoprotein particle clearance;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0008203//cholesterol metabolic process;GO:0032375//negative regulation of cholesterol transport;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0033344//cholesterol efflux;GO:0010900//negative regulation of phosphatidylcholine catabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0006629//lipid metabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:0010873//positive regulation of cholesterol esterification;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0033700//phospholipid efflux;GO:0006641//triglyceride metabolic process;GO:0045833//negative regulation of lipid metabolic process;GO:0034382//chylomicron remnant clearance;GO:0043085//positive regulation of catalytic activity;GO:0034375//high-density lipoprotein particle remodeling;GO:0032374//regulation of cholesterol transport;GO:0042157//lipoprotein metabolic process,GO:0004859//phospholipase inhibitor activity;GO:0031210//phosphatidylcholine binding;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0005504//fatty acid binding;GO:0055102//lipase inhibitor activity,K04524//Alzheimer's disease
341019,0,0,0,0,0,30,0,0,9,0,0,0,DCDC1;doublecortin domain containing 1,-,GO:0035556//intracellular signal transduction,-,-
341032,0,0,0,0,0,1,0,47,9,0,1,0,C11orf53;chromosome 11 open reading frame 53,-,-,-,-
341056,0,0,0,0,0,0,0,0,0,0,5,0,LOC341056;SUMO1 activating enzyme subunit 1 pseudogene,-,-,-,K10684//Ubiquitin mediated proteolysis
341116,42,0,0,0,0,10,0,0,12,0,0,0,"MS4A10;membrane-spanning 4-domains, subfamily A, member 10",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
341152,0,0,0,0,0,0,0,0,10,0,0,0,"OR2AT4;olfactory receptor, family 2, subfamily AT, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
341208,77,0,0,0,26,0,23,0,92,0,30,0,HEPHL1;hephaestin-like 1,GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport,GO:0005507//copper ion binding;GO:0004322//ferroxidase activity,K14735//Mineral absorption
341277,0,0,0,5,0,11,0,0,21,0,0,0,OVCH2;ovochymase 2 (gene/pseudogene),GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding,K01312//Pancreatic secretion;Protein digestion and absorption;Influenza A;Neuroactive ligand-receptor interaction
341346,0,0,0,0,0,22,0,0,19,0,0,0,SMCO2;single-pass membrane protein with coiled-coil domains 2,GO:0016021//integral component of membrane,-,-,-
341350,0,0,54,0,0,16,0,0,53,0,0,1,OVCH1;ovochymase 1,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding,K09635//Influenza A
341359,0,0,0,0,0,0,6,0,57,0,0,0,SYT10;synaptotagmin X,GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane,GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0006810//transport,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
341392,0,0,0,0,0,0,31,0,25,0,0,0,ACSM4;acyl-CoA synthetase medium-chain family member 4,GO:0005759//mitochondrial matrix,GO:0006637//acyl-CoA metabolic process;GO:0006631//fatty acid metabolic process,GO:0005524//ATP binding;GO:0004321//fatty-acyl-CoA synthase activity;GO:0047760//butyrate-CoA ligase activity;GO:0046872//metal ion binding,K01896//Butanoate metabolism;Metabolic pathways;Lipoic acid metabolism
341405,0,0,0,0,0,0,0,0,46,0,0,0,ANKRD33;ankyrin repeat domain 33,GO:0005829//cytosol;GO:0005634//nucleus,GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0035914//skeletal muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,-,K12460//Neurotrophin signaling pathway
341416,0,0,0,0,0,0,0,0,1,0,0,0,"OR6C2;olfactory receptor, family 6, subfamily C, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
341567,0,0,0,0,0,16,0,0,6,0,0,0,"H1FNT;H1 histone family, member N, testis-specific",GO:0000790//nuclear chromatin;GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0030261//chromosome condensation;GO:0007290//spermatid nucleus elongation;GO:0035092//sperm chromatin condensation,GO:0003677//DNA binding;GO:0005524//ATP binding,-
341568,0,0,0,0,0,0,18,0,35,149,0,0,"OR8S1;olfactory receptor, family 8, subfamily S, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3416,0,5,0,58,131,0,20,0,0,0,0,0,IDE;insulin-degrading enzyme,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005782//peroxisomal matrix;GO:0005634//nucleus;GO:0031597//cytosolic proteasome complex;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm,GO:0050435//beta-amyloid metabolic process;GO:1901143//insulin catabolic process;GO:0010815//bradykinin catabolic process;GO:0010992//ubiquitin homeostasis;GO:0051260//protein homooligomerization;GO:0045861//negative regulation of proteolysis;GO:0051289//protein homotetramerization;GO:0042447//hormone catabolic process;GO:0006508//proteolysis;GO:0008286//insulin receptor signaling pathway;GO:0008340//determination of adult lifespan;GO:0051291//protein heterooligomerization;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:1901142//insulin metabolic process;GO:0006200//ATP catabolic process;GO:0016032//viral process;GO:0032461//positive regulation of protein oligomerization,GO:0043130//ubiquitin binding;GO:0005102//receptor binding;GO:0001540//beta-amyloid binding;GO:0031626//beta-endorphin binding;GO:0042277//peptide binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043559//insulin binding;GO:0001948//glycoprotein binding;GO:0004222//metalloendopeptidase activity;GO:0005524//ATP binding;GO:0016887//ATPase activity,K01408//Alzheimer's disease
341640,100,0,0,0,3,72,32,0,83,61,2,0,FREM2;FRAS1 related extracellular matrix protein 2,GO:0005604//basement membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007154//cell communication;GO:0002009//morphogenesis of an epithelium;GO:0048839//inner ear development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
341676,169,0,0,0,0,12,0,139,37,0,1,0,NEK5;NIMA-related kinase 5,-,GO:0006468//protein phosphorylation;GO:0051155//positive regulation of striated muscle cell differentiation;GO:2001056//positive regulation of cysteine-type endopeptidase activity,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity,-
3417,0,153,3,487,973,0,0,0,25,0,0,3,"IDH1;isocitrate dehydrogenase 1 (NADP+), soluble",GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006740//NADPH regeneration;GO:0044255//cellular lipid metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006979//response to oxidative stress;GO:0006099//tricarboxylic acid cycle;GO:0048545//response to steroid hormone;GO:0008585//female gonad development;GO:0006102//isocitrate metabolic process;GO:0006749//glutathione metabolic process;GO:0006097//glyoxylate cycle,GO:0042803//protein homodimerization activity;GO:0051287//NAD binding;GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0050661//NADP binding;GO:0005102//receptor binding;GO:0000287//magnesium ion binding,K00031//Glutathione metabolism;Peroxisome;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Two-component system;Citrate cycle (TCA cycle);Metabolic pathways;Carbon fixation pathways in prokaryotes
341799,0,0,0,0,0,0,0,0,4,0,0,0,"OR6S1;olfactory receptor, family 6, subfamily S, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3418,0,3,0,38,66,8,1,0,18,0,9,0,"IDH2;isocitrate dehydrogenase 2 (NADP+), mitochondrial",GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044281//small molecule metabolic process;GO:0006102//isocitrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006097//glyoxylate cycle;GO:0006103//2-oxoglutarate metabolic process,GO:0051287//NAD binding;GO:0004450//isocitrate dehydrogenase (NADP+) activity;GO:0000287//magnesium ion binding,K00031//Biosynthesis of secondary metabolites;Glutathione metabolism;Peroxisome;Microbial metabolism in diverse environments;Two-component system;Carbon fixation pathways in prokaryotes;Citrate cycle (TCA cycle);Metabolic pathways
341880,0,0,0,0,0,4,0,0,23,0,0,0,"SLC35F4;solute carrier family 35, member F4",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
341883,0,47,32,47,30,5,39,0,89,0,35,0,LRRC9;leucine rich repeat containing 9,-,-,-,-
3419,0,1,0,0,64,0,0,0,37,0,11,0,IDH3A;isocitrate dehydrogenase 3 (NAD+) alpha,GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0005975//carbohydrate metabolic process,GO:0000287//magnesium ion binding;GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0051287//NAD binding,K00030//Biosynthesis of secondary metabolites;Metabolic pathways;Citrate cycle (TCA cycle);Microbial metabolism in diverse environments
341947,0,0,0,0,0,0,0,0,7,0,0,0,COX8C;cytochrome c oxidase subunit VIIIC,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:1902600//hydrogen ion transmembrane transport,GO:0004129//cytochrome-c oxidase activity,K02273//Metabolic pathways;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease;Cardiac muscle contraction
342,0,0,0,0,0,0,11,0,16,0,0,0,APOC1P1;apolipoprotein C-I pseudogene 1,-,-,-,K04524//Alzheimer's disease;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K11447//Transcriptional misregulation in cancer
3420,0,0,0,2,25,30,0,0,2,0,0,0,IDH3B;isocitrate dehydrogenase 3 (NAD+) beta,GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005759//mitochondrial matrix,GO:0006102//isocitrate metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006734//NADH metabolic process;GO:0044281//small molecule metabolic process,GO:0004449//isocitrate dehydrogenase (NAD+) activity;GO:0000287//magnesium ion binding;GO:0051287//NAD binding;GO:0009055//electron carrier activity,K00030//Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Metabolic pathways;Citrate cycle (TCA cycle)
342035,0,0,0,8,0,67,0,0,28,0,13,9,GLDN;gliomedin,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0005581//collagen trimer,GO:0032528//microvillus organization;GO:0045162//clustering of voltage-gated sodium channels;GO:0034113//heterotypic cell-cell adhesion,GO:0086080//protein binding involved in heterotypic cell-cell adhesion,-
342096,0,0,0,0,0,3,2,6,17,0,0,0,"GOLGA6A;golgin A6 family, member A",GO:0005794//Golgi apparatus,-,-,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K12478//Tuberculosis;Phagosome;Endocytosis
3421,0,13,2,19,43,0,0,0,91,4,35,0,IDH3G;isocitrate dehydrogenase 3 (NAD+) gamma,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005730//nucleolus,GO:0006102//isocitrate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,GO:0051287//NAD binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004449//isocitrate dehydrogenase (NAD+) activity,K00030//Microbial metabolism in diverse environments;Citrate cycle (TCA cycle);Metabolic pathways;Biosynthesis of secondary metabolites
342125,0,0,43,17,16,7,30,101,2,192,73,0,TMC3;transmembrane channel-like 3,GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
342132,0,0,0,0,0,21,0,0,1,0,0,0,ZNF774;zinc finger protein 774,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
342184,47,17,1,7,107,54,17,1,88,27,0,0,FMN1;formin 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0005884//actin filament;GO:0005886//plasma membrane,GO:0045010//actin nucleation,GO:0003779//actin binding,-
3422,3,68,4,144,295,0,45,1,60,0,0,0,IDI1;isopentenyl-diphosphate delta isomerase 1,GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0008299//isoprenoid biosynthetic process;GO:0035634//response to stilbenoid;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0050992//dimethylallyl diphosphate biosynthetic process,GO:0046872//metal ion binding;GO:0030145//manganese ion binding;GO:0000287//magnesium ion binding;GO:0004452//isopentenyl-diphosphate delta-isomerase activity;GO:0016787//hydrolase activity,K01823//Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis;Metabolic pathways
3423,0,15,2,66,242,15,27,2,53,0,13,0,IDS;iduronate 2-sulfatase,GO:0043202//lysosomal lumen,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process,GO:0046872//metal ion binding;GO:0004423//iduronate-2-sulfatase activity,K01136//Lysosome;Glycosaminoglycan degradation;Metabolic pathways
342346,109,0,0,0,0,0,0,0,54,0,0,0,C16orf96;chromosome 16 open reading frame 96,-,-,-,-
342357,0,3,0,7,30,0,9,0,18,61,2,0,ZKSCAN2;zinc finger with KRAB and SCAN domains 2,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
342371,0,58,1,2,34,17,7,0,107,0,6,5,ATXN1L;ataxin 1-like,GO:0030425//dendrite;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
342372,0,0,28,5,12,18,0,4,21,0,74,0,PKD1L3;polycystic kidney disease 1-like 3,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0050915//sensory perception of sour taste;GO:0071468//cellular response to acidic pH;GO:0006812//cation transport;GO:0007218//neuropeptide signaling pathway;GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0070588//calcium ion transmembrane transport,GO:0008324//cation transmembrane transporter activity;GO:0005262//calcium channel activity;GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0005261//cation channel activity;GO:0033040//sour taste receptor activity,-
3425,0,0,0,0,0,30,26,30,14,0,5,0,"IDUA;iduronidase, alpha-L-",GO:0043202//lysosomal lumen;GO:0070062//extracellular vesicular exosome;GO:0030135//coated vesicle,GO:0044281//small molecule metabolic process;GO:0048705//skeletal system morphogenesis;GO:0030203//glycosaminoglycan metabolic process;GO:0030209//dermatan sulfate catabolic process;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0035108//limb morphogenesis;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0048878//chemical homeostasis;GO:0005984//disaccharide metabolic process;GO:0000902//cell morphogenesis;GO:0007040//lysosome organization,GO:0005102//receptor binding;GO:0003940//L-iduronidase activity,K01217//Lysosome;Glycosaminoglycan degradation;Metabolic pathways
342510,0,0,0,0,0,20,0,0,7,0,0,0,CD300E;CD300e molecule,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0045087//innate immune response,-,-
342527,0,0,1,0,0,13,0,0,15,0,0,0,SMTNL2;smoothelin-like 2,-,-,-,K05699//Focal adhesion;Amoebiasis;Adherens junction;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);K06115//Tight junction
342574,0,0,0,0,0,8,8,0,3,0,0,0,KRT27;keratin 27,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0031069//hair follicle morphogenesis,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
3426,0,0,0,0,0,0,26,0,41,0,0,0,CFI;complement factor I,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane,"GO:0045087//innate immune response;GO:0006898//receptor-mediated endocytosis;GO:0030449//regulation of complement activation;GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis",GO:0046872//metal ion binding;GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity,K01333//Complement and coagulation cascades;Staphylococcus aureus infection
342618,72,0,0,0,0,17,0,0,9,0,6,0,SLFN14;schlafen family member 14,-,-,GO:0005524//ATP binding,-
342666,0,0,0,0,0,16,39,2,19,0,33,0,"LRRC37A11P;leucine rich repeat containing 37, member A11, pseudogene",-,-,-,K10955//Vibrio cholerae infection;Amoebiasis
342667,0,0,0,0,0,0,0,0,79,0,0,0,STAC2;SH3 and cysteine rich domain 2,-,GO:0035556//intracellular signal transduction,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
3428,0,0,0,0,0,22,40,0,11,0,1,0,"IFI16;interferon, gamma-inducible protein 16",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0040029//regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0006351//transcription, DNA-templated;GO:0042149//cellular response to glucose starvation;GO:0008283//cell proliferation;GO:0001819//positive regulation of cytokine production;GO:0032731//positive regulation of interleukin-1 beta production;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0010506//regulation of autophagy;GO:0071479//cellular response to ionizing radiation;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045824//negative regulation of innate immune response;GO:0006914//autophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030224//monocyte differentiation;GO:0030097//hemopoiesis;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0045071//negative regulation of viral genome replication;GO:0030099//myeloid cell differentiation;GO:0002218//activation of innate immune response;GO:0043392//negative regulation of DNA binding;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus",GO:0001047//core promoter binding;GO:0003690//double-stranded DNA binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042802//identical protein binding,K12971//Cytosolic DNA-sensing pathway;K12966//Cytosolic DNA-sensing pathway
342850,17,0,0,0,0,38,2,0,31,0,0,0,ANKRD62;ankyrin repeat domain 62,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K12460//Neurotrophin signaling pathway
342865,0,0,0,0,0,0,0,65,1,0,10,0,VSTM2B;V-set and transmembrane domain containing 2B,GO:0016021//integral component of membrane,-,-,-
342892,24,0,0,28,0,0,26,58,57,0,0,0,ZNF850;zinc finger protein 850,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
342897,45,0,0,0,0,15,0,0,35,0,0,0,NCCRP1;non-specific cytotoxic cell receptor protein 1 homolog (zebrafish),GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0008284//positive regulation of cell proliferation,-,K10099//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis
3429,34,0,0,0,0,0,19,0,14,0,0,0,"IFI27;interferon, alpha-inducible protein 27",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process,-,-
342900,0,0,0,0,0,0,0,0,10,0,0,0,LEUTX;leucine twenty homeobox,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
342908,0,0,0,4,18,0,0,0,7,0,2,0,ZNF404;zinc finger protein 404,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
342909,0,0,0,0,17,0,0,0,0,0,19,0,ZNF284;zinc finger protein 284,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
342918,13,0,0,0,0,0,26,0,0,0,0,0,C19orf81;chromosome 19 open reading frame 81,-,-,-,-
342926,0,0,0,0,4,24,0,0,0,0,0,0,ZNF677;zinc finger protein 677,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
342931,0,0,0,0,0,9,0,0,2,0,0,0,RFPL4A;ret finger protein-like 4A,-,-,GO:0008270//zinc ion binding,-
342933,59,0,0,0,0,0,0,0,0,0,6,0,ZSCAN5B;zinc finger and SCAN domain containing 5B,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
342945,0,51,0,0,0,0,0,0,86,0,23,0,ZSCAN22;zinc finger and SCAN domain containing 22,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
342977,0,0,0,0,0,0,0,0,0,1,0,246,NANOS3;nanos homolog 3 (Drosophila),GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body,GO:0051726//regulation of cell cycle;GO:0006417//regulation of translation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0048477//oogenesis;GO:0007281//germ cell development;GO:2001234//negative regulation of apoptotic signaling pathway,GO:0008270//zinc ion binding;GO:0003723//RNA binding,-
342979,73,21,1,0,0,0,0,49,34,0,0,0,PALM3;paralemmin 3,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0008063//Toll signaling pathway,GO:0005524//ATP binding;GO:0005515//protein binding,-
343,0,0,0,0,7,0,0,0,0,97,0,0,AQP8;aquaporin 8,GO:0043231//intracellular membrane-bounded organelle;GO:0046691//intracellular canaliculus;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0005887//integral component of plasma membrane,GO:0015722//canalicular bile acid transport;GO:0071320//cellular response to cAMP;GO:0006810//transport;GO:0006833//water transport;GO:0055085//transmembrane transport,GO:0015250//water channel activity,K09869//Bile secretion
3430,0,0,0,1,0,0,0,0,18,0,0,0,IFI35;interferon-induced protein 35,GO:0005829//cytosol;GO:0005634//nucleus,GO:0019221//cytokine-mediated signaling pathway;GO:0060337//type I interferon signaling pathway,GO:0005515//protein binding,-
343035,0,0,0,0,0,0,0,0,40,0,0,0,RD3;retinal degeneration 3,-,GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0060041//retina development in camera-type eye,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
343066,0,0,0,0,0,0,46,25,31,0,0,0,AADACL4;arylacetamide deacetylase-like 4,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
343068,0,0,0,0,0,1,0,0,1,0,0,0,PRAMEF5;PRAME family member 5,-,"GO:0008284//positive regulation of cell proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process",GO:0042974//retinoic acid receptor binding,-
343069,0,0,0,0,0,0,25,0,0,0,0,0,HNRNPCL1;heterogeneous nuclear ribonucleoprotein C-like 1,GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K12884//Spliceosome
343099,0,44,0,0,0,0,32,0,86,103,35,0,CCDC18;coiled-coil domain containing 18,-,-,-,K12478//Phagosome;Endocytosis;Tuberculosis
3431,78,0,0,0,30,0,0,0,0,0,0,0,SP110;SP110 nuclear body protein,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0016032//viral process;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity,K15413//Herpes simplex infection
343171,0,0,0,0,0,0,0,0,18,0,0,0,"OR2W3;olfactory receptor, family 2, subfamily W, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
343173,0,0,0,0,0,22,0,0,0,0,0,0,"OR2T3;olfactory receptor, family 2, subfamily T, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
343263,0,0,0,0,0,0,0,0,19,0,10,0,MYBPHL;myosin binding protein H-like,-,-,-,K12568//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
3433,0,0,0,5,1,0,15,0,18,0,0,0,IFIT2;interferon-induced protein with tetratricopeptide repeats 2,GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0035457//cellular response to interferon-alpha;GO:0051607//defense response to virus;GO:0008637//apoptotic mitochondrial changes;GO:0060337//type I interferon signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0032091//negative regulation of protein binding;GO:0043065//positive regulation of apoptotic process,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14217//Herpes simplex infection;Hepatitis C
3434,0,25,0,0,5,15,0,0,40,0,18,0,IFIT1;interferon-induced protein with tetratricopeptide repeats 1,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0051097//negative regulation of helicase activity;GO:0071360//cellular response to exogenous dsRNA;GO:0045070//positive regulation of viral genome replication;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0050689//negative regulation of defense response to virus by host;GO:0045071//negative regulation of viral genome replication;GO:0019060//intracellular transport of viral protein in host cell;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0032091//negative regulation of protein binding,GO:0005515//protein binding;GO:0003723//RNA binding,K14217//Herpes simplex infection;Hepatitis C
343450,0,0,0,0,0,0,23,0,10,0,0,0,"KCNT2;potassium channel, subfamily T, member 2",GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport,GO:0005249//voltage-gated potassium channel activity;GO:0005524//ATP binding;GO:0015269//calcium-activated potassium channel activity,-
343472,0,0,0,0,0,0,14,0,30,0,0,0,BARHL2;BarH-like homeobox 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0030516//regulation of axon extension;GO:0045727//positive regulation of translation;GO:0001709//cell fate determination;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001764//neuron migration;GO:0030182//neuron differentiation",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0043565//sequence-specific DNA binding,-
343505,0,0,0,0,0,0,0,0,12,0,2,0,"NBPF7;neuroblastoma breakpoint family, member 7",GO:0005737//cytoplasm,-,-,-
343563,0,0,0,0,0,0,0,0,15,0,0,0,"OR2T29;olfactory receptor, family 2, subfamily T, member 29",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
343578,57,0,0,0,0,0,0,0,46,0,0,0,ARHGAP40;Rho GTPase activating protein 40,GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K08773//Pathways in cancer;Pancreatic cancer;K08878//Chronic myeloid leukemia;Pathways in cancer
343637,0,0,0,2,0,0,16,0,14,0,8,0,RSPO4;R-spondin 4,GO:0005576//extracellular region,GO:0016055//Wnt signaling pathway,GO:0008201//heparin binding,-
343641,0,0,0,0,0,0,9,3,4,0,0,0,TGM6;transglutaminase 6,GO:0005737//cytoplasm,GO:0018149//peptide cross-linking;GO:0008219//cell death,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding,-
3437,0,0,0,0,0,14,0,0,0,161,8,0,IFIT3;interferon-induced protein with tetratricopeptide repeats 3,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0035457//cellular response to interferon-alpha;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding;GO:0042802//identical protein binding,K14217//Hepatitis C;Herpes simplex infection
343702,0,0,20,0,0,0,0,0,79,0,7,0,"XKR7;XK, Kell blood group complex subunit-related family, member 7",GO:0016021//integral component of membrane,-,-,-
3439,0,0,0,0,0,0,0,0,0,4,0,0,"IFNA1;interferon, alpha 1",-,-,-,K05414//RIG-I-like receptor signaling pathway;Measles;Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Hepatitis C;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Toll-like receptor signaling pathway;Influenza A;Tuberculosis;Jak-STAT signaling pathway;Autoimmune thyroid disease;Regulation of autophagy
343930,0,0,0,0,0,0,0,0,14,0,0,0,MSGN1;mesogenin 1,GO:0005634//nucleus,"GO:0001756//somitogenesis;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007379//segment specification;GO:0030154//cell differentiation",GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0046983//protein dimerization activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
343990,0,0,0,0,10,23,0,0,48,13,26,0,KIAA1211L;KIAA1211-like,-,-,-,-
344018,80,0,0,0,0,0,0,0,0,0,0,0,FIGLA;folliculogenesis specific basic helix-loop-helix,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0048599//oocyte development;GO:0007275//multicellular organismal development",GO:0046983//protein dimerization activity;GO:0043565//sequence-specific DNA binding;GO:0008134//transcription factor binding,-
344022,0,0,0,0,0,9,0,0,0,0,0,0,NOTO;notochord homeobox,GO:0005634//nucleus,"GO:0009953//dorsal/ventral pattern formation;GO:0006351//transcription, DNA-templated;GO:0060271//cilium morphogenesis;GO:0030903//notochord development;GO:0007368//determination of left/right symmetry;GO:0009880//embryonic pattern specification;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
3441,0,0,0,0,0,0,30,0,0,0,0,0,"IFNA4;interferon, alpha 4",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0045343//regulation of MHC class I biosynthetic process;GO:0045087//innate immune response;GO:0042100//B cell proliferation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0002286//T cell activation involved in immune response;GO:0009615//response to virus;GO:0002323//natural killer cell activation involved in immune response;GO:0002250//adaptive immune response;GO:0043330//response to exogenous dsRNA;GO:0051607//defense response to virus;GO:0030183//B cell differentiation;GO:0060337//type I interferon signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0007596//blood coagulation;GO:0006959//humoral immune response,GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding,K05414//RIG-I-like receptor signaling pathway;Measles;Hepatitis C;Cytosolic DNA-sensing pathway;Cytokine-cytokine receptor interaction;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Influenza A;Toll-like receptor signaling pathway;Tuberculosis;Jak-STAT signaling pathway;Autoimmune thyroid disease;Regulation of autophagy
344148,0,0,0,0,0,23,0,61,93,0,0,0,NCKAP5;NCK-associated protein 5,-,-,-,K10955//Amoebiasis;Vibrio cholerae infection
344167,8,0,0,0,0,0,0,0,9,0,0,0,FOXI3;forkhead box I3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
344191,0,0,56,0,0,17,0,0,1,0,0,0,EVX2;even-skipped homeobox 2,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0035108//limb morphogenesis",GO:0043565//sequence-specific DNA binding,-
3442,0,0,0,0,0,0,0,111,0,0,0,0,"IFNA5;interferon, alpha 5",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0060337//type I interferon signaling pathway;GO:0042100//B cell proliferation;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0030183//B cell differentiation;GO:0045343//regulation of MHC class I biosynthetic process;GO:0007596//blood coagulation;GO:0002250//adaptive immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0006959//humoral immune response;GO:0043330//response to exogenous dsRNA;GO:0002286//T cell activation involved in immune response;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway,GO:0005126//cytokine receptor binding;GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding,K05414//Cytosolic DNA-sensing pathway;Cytokine-cytokine receptor interaction;Hepatitis C;Herpes simplex infection;Natural killer cell mediated cytotoxicity;RIG-I-like receptor signaling pathway;Measles;Jak-STAT signaling pathway;Autoimmune thyroid disease;Regulation of autophagy;Toll-like receptor signaling pathway;Influenza A;Tuberculosis
344387,0,0,0,0,0,0,0,0,45,0,0,0,CDKL4;cyclin-dependent kinase-like 4,GO:0005737//cytoplasm,GO:0051726//regulation of cell cycle;GO:0006468//protein phosphorylation,GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
344405,0,0,0,0,0,0,43,0,0,0,0,0,"PRORSD1P;prolyl-tRNA synthetase associated domain containing 1, pseudogene",-,GO:0006450//regulation of translational fidelity,GO:0002161//aminoacyl-tRNA editing activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
344454,0,0,0,11,0,0,0,0,0,1,0,0,AOX2P;aldehyde oxidase 2 pseudogene,-,-,-,"K00157//Vitamin B6 metabolism;Tyrosine metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Valine, leucine and isoleucine degradation;Nicotinate and nicotinamide metabolism;Tryptophan metabolism"
344558,0,0,0,0,0,29,68,49,12,1,18,0,SH3RF3;SH3 domain containing ring finger 3,-,-,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
344561,0,0,0,0,11,0,58,0,14,0,0,0,GPR148;G protein-coupled receptor 148,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
3446,0,0,0,0,0,0,43,0,0,0,0,0,"IFNA10;interferon, alpha 10",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0019221//cytokine-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0002286//T cell activation involved in immune response;GO:0006959//humoral immune response;GO:0043330//response to exogenous dsRNA;GO:0002323//natural killer cell activation involved in immune response;GO:0002250//adaptive immune response;GO:0007596//blood coagulation;GO:0045343//regulation of MHC class I biosynthetic process;GO:0030183//B cell differentiation;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0042100//B cell proliferation;GO:0060337//type I interferon signaling pathway;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein,GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity,K05414//Herpes simplex infection;Natural killer cell mediated cytotoxicity;Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Hepatitis C;Measles;RIG-I-like receptor signaling pathway;Regulation of autophagy;Autoimmune thyroid disease;Jak-STAT signaling pathway;Tuberculosis;Toll-like receptor signaling pathway;Influenza A
344657,0,0,0,0,0,0,0,0,0,82,0,0,LRRIQ4;leucine-rich repeats and IQ motif containing 4,-,-,-,K12796//NOD-like receptor signaling pathway
344658,0,0,0,0,0,0,0,0,15,0,11,0,SAMD7;sterile alpha motif domain containing 7,-,-,-,-
344752,0,0,40,0,0,20,0,0,12,0,0,0,AADACL2;arylacetamide deacetylase-like 2,GO:0016021//integral component of membrane;GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
344758,0,0,0,0,0,6,0,0,24,0,0,0,GPR149;G protein-coupled receptor 149,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001547//antral ovarian follicle growth;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001546//preantral ovarian follicle growth;GO:0060280//negative regulation of ovulation;GO:0060206//estrous cycle phase,GO:0004930//G-protein coupled receptor activity,-
344787,0,0,0,3,11,12,0,0,0,0,20,0,ZNF860;zinc finger protein 860,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
3448,0,0,0,0,0,0,0,0,2,0,0,0,"IFNA14;interferon, alpha 14",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0045343//regulation of MHC class I biosynthetic process;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0060337//type I interferon signaling pathway;GO:0042100//B cell proliferation;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0002286//T cell activation involved in immune response;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0006959//humoral immune response;GO:0043330//response to exogenous dsRNA;GO:0002250//adaptive immune response;GO:0007596//blood coagulation;GO:0002323//natural killer cell activation involved in immune response,GO:0005126//cytokine receptor binding;GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding,K05414//Regulation of autophagy;Autoimmune thyroid disease;Jak-STAT signaling pathway;Tuberculosis;Influenza A;Toll-like receptor signaling pathway;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Hepatitis C;Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Measles;RIG-I-like receptor signaling pathway
344805,1,0,0,0,0,0,31,0,30,0,0,0,"TMPRSS7;transmembrane protease, serine 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
344807,0,0,0,0,0,19,0,0,0,0,0,0,CD200R1L;CD200 receptor 1-like,GO:0016021//integral component of membrane,-,-,-
344838,0,0,10,0,0,0,0,0,4,0,0,0,PAQR9;progestin and adipoQ receptor family member IX,GO:0016021//integral component of membrane,-,GO:0004872//receptor activity,K07297//Adipocytokine signaling pathway
344875,0,0,0,0,0,0,10,0,0,0,5,0,"COL6A4P1;collagen, type VI, alpha 4 pseudogene 1",-,-,-,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
344887,0,0,0,0,0,0,0,0,6,0,0,0,LOC344887;NmrA-like family domain containing 1 pseudogene,-,-,-,-
344892,0,0,0,0,0,0,0,57,0,0,0,0,RTP2;receptor (chemosensory) transporter protein 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0051205//protein insertion into membrane,GO:0031849//olfactory receptor binding,-
344905,104,0,0,0,0,0,0,72,41,0,0,0,ATP13A5;ATPase type 13A5,GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0046872//metal ion binding,-
344967,0,21,1,33,106,0,6,0,18,0,116,0,LOC344967;acyl-CoA thioesterase 7 pseudogene,GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0016290//palmitoyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity,K01068//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
345,0,0,0,0,0,0,0,0,21,0,0,0,APOC3;apolipoprotein C-III,GO:0005615//extracellular space;GO:0034361//very-low-density lipoprotein particle;GO:0034363//intermediate-density lipoprotein particle;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005576//extracellular region;GO:0042627//chylomicron;GO:0034366//spherical high-density lipoprotein particle,"GO:0034375//high-density lipoprotein particle remodeling;GO:0010897//negative regulation of triglyceride catabolic process;GO:0042157//lipoprotein metabolic process;GO:0060621//negative regulation of cholesterol import;GO:0006954//inflammatory response;GO:0045833//negative regulation of lipid metabolic process;GO:0006641//triglyceride metabolic process;GO:0033700//phospholipid efflux;GO:0043434//response to peptide hormone;GO:0007584//response to nutrient;GO:0044281//small molecule metabolic process;GO:0042953//lipoprotein transport;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0042493//response to drug;GO:0001523//retinoid metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0019433//triglyceride catabolic process;GO:0007603//phototransduction, visible light;GO:0043691//reverse cholesterol transport;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0070328//triglyceride homeostasis;GO:0010903//negative regulation of very-low-density lipoprotein particle remodeling;GO:0010989//negative regulation of low-density lipoprotein particle clearance;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0071333//cellular response to glucose stimulus;GO:0034382//chylomicron remnant clearance;GO:0042632//cholesterol homeostasis;GO:0006642//triglyceride mobilization;GO:0033344//cholesterol efflux;GO:0034379//very-low-density lipoprotein particle assembly;GO:0010987//negative regulation of high-density lipoprotein particle clearance;GO:0050995//negative regulation of lipid catabolic process",GO:0015485//cholesterol binding;GO:0055102//lipase inhibitor activity;GO:0005543//phospholipid binding;GO:0030234//enzyme regulator activity;GO:0070653//high-density lipoprotein particle receptor binding,K08759//PPAR signaling pathway
345062,0,0,23,0,0,20,0,0,4,0,5,0,"PRSS48;protease, serine, 48",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
345079,0,28,0,0,1,0,0,0,10,63,0,0,SOWAHB;sosondowah ankyrin repeat domain family member B,-,-,-,-
3451,0,0,0,0,0,33,0,0,14,0,0,0,"IFNA17;interferon, alpha 17",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0045087//innate immune response;GO:0045343//regulation of MHC class I biosynthetic process;GO:0043330//response to exogenous dsRNA;GO:0002250//adaptive immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0009615//response to virus;GO:0002286//T cell activation involved in immune response;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0030183//B cell differentiation;GO:0006959//humoral immune response;GO:0007596//blood coagulation;GO:0019221//cytokine-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway,GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding,K05414//RIG-I-like receptor signaling pathway;Measles;Hepatitis C;Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Natural killer cell mediated cytotoxicity;Herpes simplex infection;Influenza A;Toll-like receptor signaling pathway;Tuberculosis;Jak-STAT signaling pathway;Autoimmune thyroid disease;Regulation of autophagy
345193,0,0,0,0,0,26,16,0,1,0,0,0,"LRIT3;leucine-rich repeat, immunoglobulin-like and transmembrane domains 3",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0040036//regulation of fibroblast growth factor receptor signaling pathway,-,K06850//Axon guidance
3452,0,0,0,0,0,10,0,0,15,0,0,0,"IFNA21;interferon, alpha 21",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0002286//T cell activation involved in immune response;GO:0019221//cytokine-mediated signaling pathway;GO:0002323//natural killer cell activation involved in immune response;GO:0007596//blood coagulation;GO:0002250//adaptive immune response;GO:0006959//humoral immune response;GO:0043330//response to exogenous dsRNA;GO:0045343//regulation of MHC class I biosynthetic process;GO:0030183//B cell differentiation;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0060337//type I interferon signaling pathway;GO:0042100//B cell proliferation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein,GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding;GO:0005126//cytokine receptor binding,K05414//Natural killer cell mediated cytotoxicity;Herpes simplex infection;Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Hepatitis C;Measles;RIG-I-like receptor signaling pathway;Regulation of autophagy;Jak-STAT signaling pathway;Autoimmune thyroid disease;Tuberculosis;Toll-like receptor signaling pathway;Influenza A
345222,67,0,0,0,5,0,19,46,19,0,0,0,MSANTD1;Myb/SANT-like DNA-binding domain containing 1,-,-,-,-
345274,0,0,1,0,0,0,1,0,43,0,0,0,"SLC10A6;solute carrier family 10 (sodium/bile acid cotransporter), member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0043251//sodium-dependent organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport,GO:0043250//sodium-dependent organic anion transmembrane transporter activity;GO:0008508//bile acid:sodium symporter activity,-
345275,0,0,0,0,0,0,21,0,16,0,0,0,HSD17B13;hydroxysteroid (17-beta) dehydrogenase 13,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K15734//Retinol metabolism
3453,0,0,0,0,0,27,0,0,23,0,10,0,"IFNA22P;interferon, alpha 22, pseudogene",-,-,-,K05414//Tuberculosis;Influenza A;Toll-like receptor signaling pathway;Regulation of autophagy;Autoimmune thyroid disease;Jak-STAT signaling pathway;Measles;RIG-I-like receptor signaling pathway;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Hepatitis C;Cytosolic DNA-sensing pathway;Cytokine-cytokine receptor interaction
3454,0,0,0,12,10,0,43,85,10,0,0,0,"IFNAR1;interferon (alpha, beta and omega) receptor 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0042110//T cell activation;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0007259//JAK-STAT cascade;GO:0032729//positive regulation of interferon-gamma production;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0045351//type I interferon biosynthetic process,GO:0005515//protein binding;GO:0004905//type I interferon receptor activity,K05130//Cytokine-cytokine receptor interaction;Hepatitis C;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Osteoclast differentiation;Measles;Jak-STAT signaling pathway;Toll-like receptor signaling pathway;Influenza A
345456,0,0,0,0,0,0,0,0,0,3,0,0,PFN3;profilin 3,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030036//actin cytoskeleton organization,GO:0008289//lipid binding;GO:0003779//actin binding,K05759//Shigellosis;Regulation of actin cytoskeleton;Salmonella infection
345462,0,0,0,0,18,0,0,0,0,0,0,0,ZNF879;zinc finger protein 879,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
3455,0,0,0,0,8,7,0,0,11,0,13,0,"IFNAR2;interferon (alpha, beta and omega) receptor 2",GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0008283//cell proliferation;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035455//response to interferon-alpha;GO:0007259//JAK-STAT cascade,GO:0019962//type I interferon binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004905//type I interferon receptor activity,K05131//Jak-STAT signaling pathway;Toll-like receptor signaling pathway;Influenza A;Cytokine-cytokine receptor interaction;Hepatitis C;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Osteoclast differentiation;Measles
345557,0,0,0,0,0,0,24,0,24,0,18,0,"PLCXD3;phosphatidylinositol-specific phospholipase C, X domain containing 3",-,GO:0007165//signal transduction;GO:0016042//lipid catabolic process,GO:0004871//signal transducer activity;GO:0008081//phosphoric diester hydrolase activity,-
345611,0,0,0,0,0,0,0,0,32,0,0,0,"IRGM;immunity-related GTPase family, M",GO:0042995//cell projection;GO:0000421//autophagic vacuole membrane;GO:0030670//phagocytic vesicle membrane;GO:0000139//Golgi membrane;GO:0001891//phagocytic cup,GO:0045087//innate immune response;GO:0006914//autophagy;GO:0006954//inflammatory response,"GO:0016817//hydrolase activity, acting on acid anhydrides;GO:0005525//GTP binding",K14140//Toxoplasmosis;K14139//Toxoplasmosis
345643,0,0,0,0,0,21,0,0,17,0,0,0,MCIDAS;multiciliate differentiation and DNA synthesis associated cell cycle protein,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006275//regulation of DNA replication;GO:0007346//regulation of mitotic cell cycle;GO:0042384//cilium assembly;GO:0007049//cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity,-
345651,0,0,0,0,1,28,0,1,7,0,0,0,"ACTBL2;actin, beta-like 2",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,-,GO:0005524//ATP binding,K05692//Gastric acid secretion;Pathogenic Escherichia coli infection;Focal adhesion;Vibrio cholerae infection;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Phototransduction - fly;Adherens junction;Viral myocarditis;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Salmonella infection;Phagosome
345757,0,43,0,7,0,0,0,0,0,0,0,0,"FAM174A;family with sequence similarity 174, member A",GO:0016021//integral component of membrane,-,-,-
345778,5,44,0,66,123,32,19,96,0,136,0,0,MTX3;metaxin 3,GO:0005741//mitochondrial outer membrane,GO:0006626//protein targeting to mitochondrion,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
3458,0,0,0,0,0,0,0,0,0,32,0,0,"IFNG;interferon, gamma",GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:2000309//positive regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0009615//response to virus;GO:0042742//defense response to bacterium;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0060550//positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity;GO:0031642//negative regulation of myelination;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0071351//cellular response to interleukin-18;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0032747//positive regulation of interleukin-23 production;GO:0051712//positive regulation of killing of cells of other organism;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0008284//positive regulation of cell proliferation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0032700//negative regulation of interleukin-17 production;GO:0007166//cell surface receptor signaling pathway;GO:0002026//regulation of the force of heart contraction;GO:0045666//positive regulation of neuron differentiation;GO:0007050//cell cycle arrest;GO:0032224//positive regulation of synaptic transmission, cholinergic;GO:0071222//cellular response to lipopolysaccharide;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0060557//positive regulation of vitamin D biosynthetic process;GO:0050796//regulation of insulin secretion;GO:0045672//positive regulation of osteoclast differentiation;GO:0030593//neutrophil chemotaxis;GO:0002250//adaptive immune response;GO:0019882//antigen processing and presentation;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0060559//positive regulation of calcidiol 1-monooxygenase activity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002302//CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0042832//defense response to protozoan;GO:0044130//negative regulation of growth of symbiont in host;GO:0042493//response to drug;GO:0001781//neutrophil apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0006928//cellular component movement;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0006959//humoral immune response;GO:0060552//positive regulation of fructose 1,6-bisphosphate metabolic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0045785//positive regulation of cell adhesion;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000060//protein import into nucleus, translocation;GO:0042102//positive regulation of T cell proliferation;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0051607//defense response to virus",GO:0005133//interferon-gamma receptor binding;GO:0005125//cytokine activity,K04687//Graft-versus-host disease;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation;Measles;Antigen processing and presentation;Jak-STAT signaling pathway;Malaria;Regulation of autophagy;Chagas disease (American trypanosomiasis);Type I diabetes mellitus;Proteasome;TGF-beta signaling pathway;Cytokine-cytokine receptor interaction;Allograft rejection;T cell receptor signaling pathway;Systemic lupus erythematosus;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Amoebiasis;Epstein-Barr virus infection;Salmonella infection;Rheumatoid arthritis;Influenza A;Tuberculosis;African trypanosomiasis
345895,0,0,0,14,0,0,0,0,21,0,0,0,RSPH4A;radial spoke head 4 homolog A (Chlamydomonas),GO:0031514//motile cilium;GO:0005730//nucleolus;GO:0001534//radial spoke;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005930//axoneme,GO:0035082//axoneme assembly;GO:0003341//cilium movement,-,K04700//Jak-STAT signaling pathway
3459,135,0,0,1,0,0,0,0,1,0,0,0,IFNGR1;interferon gamma receptor 1,GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0031982//vesicle;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0007165//signal transduction;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway,GO:0019955//cytokine binding;GO:0004906//interferon-gamma receptor activity;GO:0005515//protein binding,K05132//Cytokine-cytokine receptor interaction;Natural killer cell mediated cytotoxicity;Herpes simplex infection;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation;Measles;Salmonella infection;Jak-STAT signaling pathway;Chagas disease (American trypanosomiasis);Influenza A;Tuberculosis
345930,0,0,0,0,0,0,0,0,41,193,19,1,ECT2L;epithelial cell transforming 2 like,-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
3460,28,18,0,9,36,0,0,39,12,0,6,0,IFNGR2;interferon gamma receptor 2 (interferon gamma transducer 1),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum,GO:0060333//interferon-gamma-mediated signaling pathway;GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway,GO:0004906//interferon-gamma receptor activity,K05133//Chagas disease (American trypanosomiasis);Jak-STAT signaling pathway;Salmonella infection;Tuberculosis;Influenza A;Leishmaniasis;Osteoclast differentiation;Toxoplasmosis;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Cytokine-cytokine receptor interaction;Measles
346007,107,0,0,3,10,176,19,11,67,0,11,0,EYS;eyes shut homolog (Drosophila),GO:0070062//extracellular vesicular exosome,GO:0043403//skeletal muscle tissue regeneration;GO:0050908//detection of light stimulus involved in visual perception,GO:0005509//calcium ion binding,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
346157,0,0,0,0,7,0,29,0,0,0,7,0,ZNF391;zinc finger protein 391,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
346171,0,0,0,0,0,0,0,0,1,0,0,0,ZFP57;ZFP57 zinc finger protein,GO:0005720//nuclear heterochromatin,"GO:0043045//DNA methylation involved in embryo development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007422//peripheral nervous system development;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
346288,0,0,0,0,0,0,0,0,3,0,0,0,SEPT14;septin 14,GO:0031105//septin complex,GO:0007049//cell cycle;GO:0051301//cell division,GO:0005515//protein binding;GO:0005525//GTP binding,K04557//Parkinson's disease
346389,23,0,0,0,0,23,9,0,53,0,6,0,MACC1;metastasis associated in colon cancer 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0051781//positive regulation of cell division;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008083//growth factor activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
346525,0,0,0,0,0,2,0,0,0,0,0,0,"OR2A12;olfactory receptor, family 2, subfamily A, member 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
346562,0,0,0,0,0,0,0,0,16,0,0,0,"GNAT3;guanine nucleotide binding protein, alpha transducing 3",GO:0001669//acrosomal vesicle;GO:0005930//axoneme;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex;GO:0016324//apical plasma membrane;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0043234//protein complex,GO:0050916//sensory perception of sweet taste;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0035094//response to nicotine;GO:0007596//blood coagulation;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0006184//GTP catabolic process;GO:0050917//sensory perception of umami taste;GO:0009584//detection of visible light;GO:0007268//synaptic transmission,GO:0046872//metal ion binding;GO:0008020//G-protein coupled photoreceptor activity;GO:0001664//G-protein coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0031683//G-protein beta/gamma-subunit complex binding,K04631//Carbohydrate digestion and absorption;Phototransduction;Taste transduction
346606,0,0,0,0,6,0,0,13,28,0,0,0,MOGAT3;monoacylglycerol O-acyltransferase 3,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006071//glycerol metabolic process;GO:0019432//triglyceride biosynthetic process,GO:0003846//2-acylglycerol O-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity,K14456//Glycerolipid metabolism;Fat digestion and absorption;Metabolic pathways
346653,0,0,0,0,0,6,15,0,7,0,0,0,"FAM71F2;family with sequence similarity 71, member F2",-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
346673,0,0,0,0,0,23,0,0,5,0,6,0,STRA8;stimulated by retinoic acid 8,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007066//female meiosis sister chromatid cohesion;GO:0048599//oocyte development;GO:0033315//meiotic DNA replication checkpoint;GO:0010032//meiotic chromosome condensation;GO:0007131//reciprocal meiotic recombination;GO:0009566//fertilization;GO:0007283//spermatogenesis;GO:0006260//DNA replication;GO:0042138//meiotic DNA double-strand break formation;GO:0046620//regulation of organ growth;GO:0007129//synapsis;GO:0001541//ovarian follicle development;GO:0071300//cellular response to retinoic acid,GO:0046983//protein dimerization activity,-
346689,0,0,0,3,0,18,19,0,0,173,0,0,"KLRG2;killer cell lectin-like receptor subfamily G, member 2",GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
3467,0,0,0,0,0,0,35,0,18,0,0,0,"IFNW1;interferon, omega 1",GO:0005615//extracellular space,GO:0007050//cell cycle arrest;GO:0045343//regulation of MHC class I biosynthetic process;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0030183//B cell differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0002286//T cell activation involved in immune response;GO:0006959//humoral immune response;GO:0043330//response to exogenous dsRNA;GO:0002250//adaptive immune response;GO:0002323//natural killer cell activation involved in immune response,GO:0005132//type I interferon receptor binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding,K05440//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;RIG-I-like receptor signaling pathway
347,0,0,0,0,0,4,0,0,0,0,0,0,APOD;apolipoprotein D,GO:0043025//neuronal cell body;GO:0022626//cytosolic ribosome;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0005615//extracellular space,GO:2000405//negative regulation of T cell migration;GO:0006006//glucose metabolic process;GO:0007568//aging;GO:0042246//tissue regeneration;GO:0060588//negative regulation of lipoprotein lipid oxidation;GO:0014012//peripheral nervous system axon regeneration;GO:0006869//lipid transport;GO:0048678//response to axon injury;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:0071638//negative regulation of monocyte chemotactic protein-1 production;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0000302//response to reactive oxygen species;GO:0051895//negative regulation of focal adhesion assembly;GO:0001525//angiogenesis;GO:0042308//negative regulation of protein import into nucleus;GO:0042493//response to drug;GO:0006629//lipid metabolic process;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:0007420//brain development;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0015485//cholesterol binding;GO:0005319//lipid transporter activity,-
347051,0,0,0,0,0,0,30,0,16,0,0,0,"SLC10A5;solute carrier family 10, member 5",GO:0016021//integral component of membrane,GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport,GO:0008508//bile acid:sodium symporter activity,-
347127,0,0,0,0,0,16,0,0,7,0,0,0,"SPATA31D5P;SPATA31 subfamily D, member 5, pseudogene",-,-,-,-
347148,0,0,0,0,0,0,0,0,0,0,10,0,QRFP;pyroglutamylated RFamide peptide,GO:0005576//extracellular region,GO:0045777//positive regulation of blood pressure;GO:0007218//neuropeptide signaling pathway;GO:0060259//regulation of feeding behavior;GO:0007626//locomotory behavior;GO:0007625//grooming behavior,GO:0005184//neuropeptide hormone activity;GO:0031854//orexigenic neuropeptide QRFP receptor binding,-
347168,34,0,0,0,0,0,0,0,0,0,0,0,"OR1J1;olfactory receptor, family 1, subfamily J, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
347169,0,0,0,0,0,2,0,0,24,0,0,0,"OR1B1;olfactory receptor, family 1, subfamily B, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
347240,0,0,0,6,0,17,19,0,53,0,3,0,KIF24;kinesin family member 24,GO:0043234//protein complex;GO:0005874//microtubule;GO:0005814//centriole;GO:0005871//kinesin complex,GO:0008152//metabolic process;GO:0042384//cilium assembly;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization,GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
347252,0,0,0,0,0,0,0,0,13,0,0,0,IGFBPL1;insulin-like growth factor binding protein-like 1,GO:0005576//extracellular region,GO:0001558//regulation of cell growth,GO:0005520//insulin-like growth factor binding,K11447//Transcriptional misregulation in cancer
347273,0,0,0,0,0,0,0,0,0,0,18,0,MURC;muscle-related coiled-coil protein,GO:0030018//Z disc,"GO:0007517//muscle organ development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation",-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
347344,0,0,0,3,19,0,0,0,37,0,0,0,ZNF81;zinc finger protein 81,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
347365,0,0,1,0,0,10,0,0,59,0,13,0,"ITIH6;inter-alpha-trypsin inhibitor heavy chain family, member 6",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process,GO:0004867//serine-type endopeptidase inhibitor activity,K04574//Amyotrophic lateral sclerosis (ALS);K13909//Salivary secretion;K05316//MAPK signaling pathway
347404,0,0,0,0,0,26,0,0,68,0,0,0,LANCL3;LanC lantibiotic synthetase component C-like 3 (bacterial),-,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
347411,0,0,0,0,0,0,0,0,2,0,0,0,MPC1L;mitochondrial pyruvate carrier 1-like,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006850//mitochondrial pyruvate transport,-,-
347442,0,0,1,0,0,0,0,0,20,0,0,0,DCAF8L2;DDB1 and CUL4 associated factor 8-like 2,-,-,-,-
347454,0,0,0,3,0,0,0,0,14,0,0,0,SOWAHD;sosondowah ankyrin repeat domain family member D,-,-,-,-
347475,0,0,0,0,0,0,0,0,23,0,0,0,CCDC160;coiled-coil domain containing 160,-,-,-,-
3475,0,0,0,0,22,2,0,0,46,0,0,0,IFRD1;interferon-related developmental regulator 1,GO:0005634//nucleus,GO:0007518//myoblast fate determination;GO:0007275//multicellular organismal development;GO:0007527//adult somatic muscle development,-,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways
347516,0,0,0,0,0,0,17,0,15,0,0,0,DGAT2L6;diacylglycerol O-acyltransferase 2-like 6,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006629//lipid metabolic process,"GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups",-
347517,0,65,0,34,20,0,0,0,0,0,0,0,"RAB41;RAB41, member RAS oncogene family",GO:0005737//cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005525//GTP binding,-
347527,0,0,0,0,0,0,33,0,53,0,0,0,"ARSH;arylsulfatase family, member H",GO:0005788//endoplasmic reticulum lumen;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0044267//cellular protein metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process,GO:0004065//arylsulfatase activity;GO:0046872//metal ion binding,-
3476,0,0,0,28,32,0,0,0,11,0,0,0,IGBP1;immunoglobulin (CD79A) binding protein 1,GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0042113//B cell activation;GO:0035308//negative regulation of protein dephosphorylation;GO:0007165//signal transduction;GO:0070555//response to interleukin-1;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035306//positive regulation of dephosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060632//regulation of microtubule-based movement;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0034612//response to tumor necrosis factor;GO:0032873//negative regulation of stress-activated MAPK cascade,GO:0008601//protein phosphatase type 2A regulator activity;GO:0005515//protein binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0019904//protein domain specific binding,-
347688,0,0,0,0,0,2,0,0,38,0,1,0,"TUBB8;tubulin, beta 8 class VIII",GO:0070062//extracellular vesicular exosome;GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0051258//protein polymerization;GO:0006184//GTP catabolic process;GO:0007017//microtubule-based process,GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07375//Gap junction;Phagosome;Pathogenic Escherichia coli infection
347694,0,0,0,0,0,11,18,70,14,0,0,0,"ECEL1P2;endothelin converting enzyme-like 1, pseudogene 2",-,-,-,-
347731,186,0,0,0,0,0,53,0,22,0,0,0,LRRTM3;leucine rich repeat transmembrane neuronal 3,GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,GO:1902004//positive regulation of beta-amyloid formation,-,K07523//Axon guidance
347732,0,0,0,0,0,0,16,0,0,0,0,0,"CATSPER3;cation channel, sperm associated 3",GO:0031514//motile cilium;GO:0005886//plasma membrane;GO:0001669//acrosomal vesicle;GO:0005783//endoplasmic reticulum;GO:0036128//CatSper complex,GO:0035036//sperm-egg recognition;GO:0034765//regulation of ion transmembrane transport;GO:0030317//sperm motility;GO:0007275//multicellular organismal development;GO:0070588//calcium ion transmembrane transport;GO:0032504//multicellular organism reproduction;GO:0048240//sperm capacitation;GO:0007338//single fertilization;GO:0006814//sodium ion transport;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import,GO:0005227//calcium activated cation channel activity;GO:0005245//voltage-gated calcium channel activity,-
347733,0,0,0,0,0,0,28,0,27,0,0,0,"TUBB2B;tubulin, beta 2B class IIb",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process;GO:0051258//protein polymerization;GO:0001764//neuron migration;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome
347734,0,0,2,0,2,0,0,0,0,120,1,0,"SLC35B2;solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006805//xenobiotic metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:1902559//3'-phospho-5'-adenylyl sulfate transmembrane transport;GO:0055085//transmembrane transport,GO:0046964//3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity;GO:0004871//signal transducer activity,-
347735,80,0,0,0,1,6,0,61,21,61,24,0,SERINC2;serine incorporator 2,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0006665//sphingolipid metabolic process;GO:0015825//L-serine transport;GO:0051347//positive regulation of transferase activity;GO:0006658//phosphatidylserine metabolic process,GO:0015194//L-serine transmembrane transporter activity,-
347736,0,0,0,0,0,0,0,24,15,0,16,0,NME9;NME/NM23 family member 9,GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0006165//nucleoside diphosphate phosphorylation;GO:0006228//UTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0006183//GTP biosynthetic process;GO:0045454//cell redox homeostasis,GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding,K00940//Bacterial invasion of epithelial cells;Metabolic pathways;Shigellosis;Purine metabolism;Nitrogen metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
347741,0,0,0,0,0,34,29,0,8,0,0,0,OTOP3;otopetrin 3,GO:0016021//integral component of membrane,-,GO:0046872//metal ion binding,-
347744,0,36,89,85,205,0,0,0,16,0,92,1,C6orf52;chromosome 6 open reading frame 52,-,-,-,-
347853,0,0,0,0,0,31,23,4,18,0,6,0,TBX10;T-box 10,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
347862,0,0,0,0,0,0,1,0,12,0,11,0,PDDC1;Parkinson disease 7 domain containing 1,GO:0070062//extracellular vesicular exosome,-,-,K11447//Transcriptional misregulation in cancer
3479,0,0,0,0,0,0,0,0,44,0,2,0,IGF1;insulin-like growth factor 1 (somatomedin C),GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016942//insulin-like growth factor binding protein complex,"GO:0043388//positive regulation of DNA binding;GO:0048754//branching morphogenesis of an epithelial tube;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048146//positive regulation of fibroblast proliferation;GO:0045821//positive regulation of glycolytic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0060510//Type II pneumocyte differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0014911//positive regulation of smooth muscle cell migration;GO:0051450//myoblast proliferation;GO:0007596//blood coagulation;GO:0001501//skeletal system development;GO:0007517//muscle organ development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0014904//myotube cell development;GO:0002576//platelet degranulation;GO:0060426//lung vasculature development;GO:0040014//regulation of multicellular organism growth;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:2000288//positive regulation of myoblast proliferation;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0045740//positive regulation of DNA replication;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0006928//cellular component movement;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0007165//signal transduction;GO:0001775//cell activation;GO:0046326//positive regulation of glucose import;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0008284//positive regulation of cell proliferation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007265//Ras protein signal transduction;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0045840//positive regulation of mitosis;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0030104//water homeostasis;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0030168//platelet activation;GO:0048839//inner ear development;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0035264//multicellular organism growth;GO:0060463//lung lobe morphogenesis;GO:0060509//Type I pneumocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030166//proteoglycan biosynthetic process;GO:0048286//lung alveolus development;GO:0001974//blood vessel remodeling;GO:0060741//prostate gland stromal morphogenesis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0060736//prostate gland growth;GO:0044267//cellular protein metabolic process;GO:0006260//DNA replication;GO:0030879//mammary gland development;GO:0031017//exocrine pancreas development;GO:0035630//bone mineralization involved in bone maturation;GO:0009441//glycolate metabolic process;GO:0045445//myoblast differentiation;GO:0010001//glial cell differentiation",GO:0005515//protein binding;GO:0005178//integrin binding;GO:0005179//hormone activity;GO:0008083//growth factor activity;GO:0005159//insulin-like growth factor receptor binding;GO:0005158//insulin receptor binding,K05459//Glioma;p53 signaling pathway;Focal adhesion;Hypertrophic cardiomyopathy (HCM);mTOR signaling pathway;Melanoma;Oocyte meiosis;Dilated cardiomyopathy;Aldosterone-regulated sodium reabsorption;Prostate cancer;Transcriptional misregulation in cancer;Progesterone-mediated oocyte maturation;Pathways in cancer;Long-term depression
347902,0,0,0,0,1,0,39,0,20,0,12,0,AMIGO2;adhesion molecule with Ig-like domain 2,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0043066//negative regulation of apoptotic process;GO:0043069//negative regulation of programmed cell death,GO:0005515//protein binding,K06838//Axon guidance
347918,0,0,0,0,0,14,9,0,10,0,0,0,EP400NL;EP400 N-terminal like,-,-,-,-
348,0,0,1,0,0,0,0,4,0,231,2,0,APOE;apolipoprotein E,GO:0034363//intermediate-density lipoprotein particle;GO:0031012//extracellular matrix;GO:0034362//low-density lipoprotein particle;GO:0034361//very-low-density lipoprotein particle;GO:0031982//vesicle;GO:0043025//neuronal cell body;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005770//late endosome;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031232//extrinsic component of external side of plasma membrane;GO:0071682//endocytic vesicle lumen;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0016020//membrane,"GO:0008203//cholesterol metabolic process;GO:0007603//phototransduction, visible light;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0006641//triglyceride metabolic process;GO:0033700//phospholipid efflux;GO:0014012//peripheral nervous system axon regeneration;GO:0006898//receptor-mediated endocytosis;GO:1903002//positive regulation of lipid transport across blood brain barrier;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0051055//negative regulation of lipid biosynthetic process;GO:0001937//negative regulation of endothelial cell proliferation;GO:0015909//long-chain fatty acid transport;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0034447//very-low-density lipoprotein particle clearance;GO:0017038//protein import;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:1901214//regulation of neuron death;GO:1901215//negative regulation of neuron death;GO:0007271//synaptic transmission, cholinergic;GO:0033344//cholesterol efflux;GO:0000302//response to reactive oxygen species;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0048168//regulation of neuronal synaptic plasticity;GO:0010544//negative regulation of platelet activation;GO:0042159//lipoprotein catabolic process;GO:1901630//negative regulation of presynaptic membrane organization;GO:1901627//negative regulation of postsynaptic membrane organization;GO:1903001//negative regulation of lipid transport across blood brain barrier;GO:0032489//regulation of Cdc42 protein signal transduction;GO:0034384//high-density lipoprotein particle clearance;GO:1900221//regulation of beta-amyloid clearance;GO:0042311//vasodilation;GO:0071347//cellular response to interleukin-1;GO:0048844//artery morphogenesis;GO:0051651//maintenance of location in cell;GO:0097113//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering;GO:0043524//negative regulation of neuron apoptotic process;GO:0019934//cGMP-mediated signaling;GO:1901216//positive regulation of neuron death;GO:1901631//positive regulation of presynaptic membrane organization;GO:1902430//negative regulation of beta-amyloid formation;GO:0034374//low-density lipoprotein particle remodeling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045471//response to ethanol;GO:0007010//cytoskeleton organization;GO:0032805//positive regulation of low-density lipoprotein particle receptor catabolic process;GO:0071397//cellular response to cholesterol;GO:0043691//reverse cholesterol transport;GO:0008219//cell death;GO:0001523//retinoid metabolic process;GO:0042158//lipoprotein biosynthetic process;GO:0060999//positive regulation of dendritic spine development;GO:0010873//positive regulation of cholesterol esterification;GO:0006874//cellular calcium ion homeostasis;GO:0050728//negative regulation of inflammatory response;GO:0002021//response to dietary excess;GO:0071363//cellular response to growth factor stimulus;GO:0097114//N-methyl-D-aspartate receptor clustering;GO:0043407//negative regulation of MAP kinase activity;GO:1902999//negative regulation of phospholipid efflux;GO:0046889//positive regulation of lipid biosynthetic process;GO:0055089//fatty acid homeostasis;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0034375//high-density lipoprotein particle remodeling;GO:0006707//cholesterol catabolic process;GO:1902947//regulation of tau-protein kinase activity;GO:0034380//high-density lipoprotein particle assembly;GO:0032526//response to retinoic acid;GO:1901628//positive regulation of postsynaptic membrane organization;GO:0010875//positive regulation of cholesterol efflux;GO:0042157//lipoprotein metabolic process;GO:0045773//positive regulation of axon extension;GO:1902998//positive regulation of neurofibrillary tangle assembly;GO:0090370//negative regulation of cholesterol efflux;GO:0030516//regulation of axon extension;GO:0046907//intracellular transport;GO:1902995//positive regulation of phospholipid efflux;GO:0030195//negative regulation of blood coagulation;GO:0007263//nitric oxide mediated signal transduction;GO:0042632//cholesterol homeostasis;GO:1902951//negative regulation of dendritic spine maintenance;GO:0034382//chylomicron remnant clearance;GO:1902004//positive regulation of beta-amyloid formation;GO:0061000//negative regulation of dendritic spine development;GO:1902952//positive regulation of dendritic spine maintenance;GO:0007568//aging;GO:0048709//oligodendrocyte differentiation",GO:0008289//lipid binding;GO:0046848//hydroxyapatite binding;GO:0016209//antioxidant activity;GO:0005319//lipid transporter activity;GO:0071813//lipoprotein particle binding;GO:0005543//phospholipid binding;GO:0042803//protein homodimerization activity;GO:0060228//phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0050750//low-density lipoprotein particle receptor binding;GO:0017127//cholesterol transporter activity;GO:0046911//metal chelating activity;GO:0042802//identical protein binding;GO:0048156//tau protein binding;GO:0001540//beta-amyloid binding;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding,K04524//Alzheimer's disease
3480,48,116,3,33,88,14,38,78,30,188,28,0,IGF1R;insulin-like growth factor 1 receptor,GO:0043005//neuron projection;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005901//caveola,GO:0051898//negative regulation of protein kinase B signaling;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0045840//positive regulation of mitosis;GO:0008286//insulin receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0051389//inactivation of MAPKK activity;GO:0008284//positive regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0006955//immune response;GO:0033197//response to vitamin E;GO:0043066//negative regulation of apoptotic process;GO:0007420//brain development;GO:0046328//regulation of JNK cascade;GO:0048015//phosphatidylinositol-mediated signaling;GO:0032467//positive regulation of cytokinesis;GO:0031017//exocrine pancreas development;GO:0007165//signal transduction;GO:0046777//protein autophosphorylation;GO:0060740//prostate gland epithelium morphogenesis;GO:0045740//positive regulation of DNA replication;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0030879//mammary gland development;GO:0051291//protein heterooligomerization;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030010//establishment of cell polarity;GO:0030238//male sex determination;GO:0007409//axonogenesis;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0008544//epidermis development;GO:0051262//protein tetramerization;GO:0030335//positive regulation of cell migration,GO:0043559//insulin binding;GO:0005515//protein binding;GO:0001965//G-protein alpha-subunit binding;GO:0043560//insulin receptor substrate binding;GO:0005010//insulin-like growth factor-activated receptor activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0005158//insulin receptor binding,K05087//Melanoma;Oocyte meiosis;Glioma;Adherens junction;Focal adhesion;Pathways in cancer;Long-term depression;Endocytosis;Prostate cancer;Transcriptional misregulation in cancer;Progesterone-mediated oocyte maturation
348013,0,0,0,0,0,9,0,0,6,0,0,0,TMEM255B;transmembrane protein 255B,GO:0016021//integral component of membrane,-,-,-
348021,0,0,0,0,0,0,0,17,0,140,10,0,LINC00442;long intergenic non-protein coding RNA 442,-,-,-,-
348093,0,0,0,0,0,0,18,0,0,0,0,0,RBPMS2;RNA binding protein with multiple splicing 2,-,-,GO:0000166//nucleotide binding;GO:0003676//nucleic acid binding,-
348094,0,0,0,13,35,0,0,0,37,0,5,0,ANKDD1A;ankyrin repeat and death domain containing 1A,-,GO:0007165//signal transduction,-,-
348110,0,30,0,46,144,17,0,0,9,0,0,0,ARPIN;actin-related protein 2/3 complex inhibitor,GO:0030027//lamellipodium,GO:0051126//negative regulation of actin nucleation;GO:0033058//directional locomotion;GO:2000393//negative regulation of lamellipodium morphogenesis;GO:0030336//negative regulation of cell migration,-,K12399//Lysosome;K11447//Transcriptional misregulation in cancer
348120,112,0,0,0,0,34,22,0,40,0,4,0,LINC01193;long intergenic non-protein coding RNA 1193,-,-,-,K14142//Toxoplasmosis
348158,26,0,0,0,0,0,0,0,0,1,0,0,ACSM2B;acyl-CoA synthetase medium-chain family member 2B,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006631//fatty acid metabolic process,GO:0046872//metal ion binding;GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding,K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
348174,0,0,0,0,0,0,2,0,13,0,0,0,"CLEC18A;C-type lectin domain family 18, member A",GO:0005576//extracellular region,-,GO:0030246//carbohydrate binding,-
348180,0,0,0,0,0,21,17,85,20,0,0,0,CTU2;cytosolic thiouridylase subunit 2 homolog (S. pombe),GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0002098//tRNA wobble uridine modification;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification,GO:0016779//nucleotidyltransferase activity;GO:0005515//protein binding;GO:0000049//tRNA binding,K14169//Sulfur relay system
3482,154,1,0,14,9,23,17,35,74,3,22,344,IGF2R;insulin-like growth factor 2 receptor,GO:0030118//clathrin coat;GO:0030139//endocytic vesicle;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0005770//late endosome;GO:0009986//cell surface;GO:0005641//nuclear envelope lumen;GO:0030140//trans-Golgi network transport vesicle;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0005765//lysosomal membrane,GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0009791//post-embryonic development;GO:0007165//signal transduction;GO:0001889//liver development;GO:0032526//response to retinoic acid;GO:0031100//organ regeneration,GO:0042802//identical protein binding;GO:0001948//glycoprotein binding;GO:0019899//enzyme binding;GO:0004872//receptor activity;GO:0001972//retinoic acid binding;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0031995//insulin-like growth factor II binding;GO:0051219//phosphoprotein binding;GO:0004930//G-protein coupled receptor activity;GO:0005215//transporter activity;GO:0001965//G-protein alpha-subunit binding;GO:0005010//insulin-like growth factor-activated receptor activity,K06564//Lysosome
348235,86,9,0,17,58,0,0,0,66,0,0,0,SKA2;spindle and kinetochore associated complex subunit 2,GO:0000940//condensed chromosome outer kinetochore;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005876//spindle microtubule,GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051301//cell division,GO:0008017//microtubule binding;GO:0005515//protein binding,-
348254,0,0,0,0,0,19,0,0,14,0,0,0,"CCDC144CP;coiled-coil domain containing 144C, pseudogene",-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);K12478//Tuberculosis;Endocytosis;Phagosome
348262,74,15,0,0,0,15,0,0,19,0,0,1,"FAM195B;family with sequence similarity 195, member B",-,-,-,-
3483,0,0,0,0,16,24,0,0,11,0,16,0,"IGFALS;insulin-like growth factor binding protein, acid labile subunit",GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion;GO:0007165//signal transduction,GO:0005520//insulin-like growth factor binding,K06260//Hematopoietic cell lineage;ECM-receptor interaction
348303,79,0,0,0,0,2,0,1,19,0,0,0,SELV;selenoprotein V,-,GO:0045454//cell redox homeostasis,GO:0008430//selenium binding,-
348327,0,0,0,0,0,27,0,0,22,0,16,0,ZNF530;zinc finger protein 530,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
348378,0,0,0,0,0,0,0,0,26,0,0,0,"FAM159A;family with sequence similarity 159, member A",GO:0016021//integral component of membrane,-,-,-
3484,100,0,0,0,0,0,21,0,7,0,0,0,IGFBP1;insulin-like growth factor binding protein 1,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0042246//tissue regeneration;GO:0030307//positive regulation of cell growth,GO:0005520//insulin-like growth factor binding,K10138//p53 signaling pathway;Transcriptional misregulation in cancer
348487,0,0,0,0,9,0,25,0,0,2,5,0,"FAM131C;family with sequence similarity 131, member C",-,-,-,-
3485,0,0,0,0,0,0,0,0,30,0,0,0,"IGFBP2;insulin-like growth factor binding protein 2, 36kDa",GO:0016324//apical plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0032355//response to estradiol;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0051384//response to glucocorticoid;GO:0042104//positive regulation of activated T cell proliferation;GO:0001558//regulation of cell growth;GO:0010226//response to lithium ion;GO:0042493//response to drug;GO:0032870//cellular response to hormone stimulus;GO:0007565//female pregnancy;GO:0032526//response to retinoic acid;GO:0007568//aging;GO:0044267//cellular protein metabolic process;GO:0009612//response to mechanical stimulus;GO:0007584//response to nutrient,GO:0031995//insulin-like growth factor II binding;GO:0005515//protein binding;GO:0031994//insulin-like growth factor I binding,K10138//p53 signaling pathway;Transcriptional misregulation in cancer
3486,0,0,0,0,0,19,0,0,0,0,0,0,IGFBP3;insulin-like growth factor binding protein 3,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0016942//insulin-like growth factor binding protein complex,GO:0008285//negative regulation of cell proliferation;GO:0014912//negative regulation of smooth muscle cell migration;GO:0001933//negative regulation of protein phosphorylation;GO:0044342//type B pancreatic cell proliferation;GO:0045663//positive regulation of myoblast differentiation;GO:0001558//regulation of cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0006468//protein phosphorylation;GO:0009968//negative regulation of signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0010906//regulation of glucose metabolic process;GO:0044267//cellular protein metabolic process;GO:0043085//positive regulation of catalytic activity;GO:0006915//apoptotic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0001649//osteoblast differentiation,GO:0008160//protein tyrosine phosphatase activator activity;GO:0001968//fibronectin binding;GO:0005520//insulin-like growth factor binding;GO:0031994//insulin-like growth factor I binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K10138//Transcriptional misregulation in cancer;p53 signaling pathway
348645,0,0,0,0,0,14,0,64,37,0,0,0,C22orf34;chromosome 22 open reading frame 34,-,-,-,-
348654,0,0,0,2,24,0,0,0,62,1,38,303,GEN1;GEN1 Holliday junction 5' flap endonuclease,GO:0005813//centrosome;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0010824//regulation of centrosome duplication;GO:0071140//resolution of mitotic recombination intermediates;GO:0000724//double-strand break repair via homologous recombination;GO:0000737//DNA catabolic process, endonucleolytic",GO:0046872//metal ion binding;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0003677//DNA binding,-
3487,0,0,0,0,0,0,0,0,34,0,5,0,IGFBP4;insulin-like growth factor binding protein 4,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0006954//inflammatory response;GO:0043410//positive regulation of MAPK cascade;GO:0001558//regulation of cell growth;GO:0006259//DNA metabolic process;GO:0044342//type B pancreatic cell proliferation;GO:0007165//signal transduction;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0001501//skeletal system development;GO:0008283//cell proliferation;GO:0010906//regulation of glucose metabolic process;GO:0044267//cellular protein metabolic process,GO:0005520//insulin-like growth factor binding,K10138//p53 signaling pathway;Transcriptional misregulation in cancer
348738,0,0,0,0,0,5,0,0,0,0,0,0,C2orf48;chromosome 2 open reading frame 48,-,-,-,-
348793,0,0,0,0,17,0,0,0,46,0,0,0,WDR53;WD repeat domain 53,-,-,-,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
3488,0,0,0,16,47,8,25,0,12,0,6,0,IGFBP5;insulin-like growth factor binding protein 5,GO:0005576//extracellular region;GO:0016942//insulin-like growth factor binding protein complex,GO:0031069//hair follicle morphogenesis;GO:0001558//regulation of cell growth;GO:0042593//glucose homeostasis;GO:0051897//positive regulation of protein kinase B signaling;GO:0044342//type B pancreatic cell proliferation;GO:0060056//mammary gland involution;GO:0071407//cellular response to organic cyclic compound;GO:0035556//intracellular signal transduction;GO:0030336//negative regulation of cell migration;GO:0014912//negative regulation of smooth muscle cell migration;GO:0048630//skeletal muscle tissue growth;GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0017148//negative regulation of translation;GO:0006006//glucose metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0045668//negative regulation of osteoblast differentiation;GO:0071320//cellular response to cAMP;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0051146//striated muscle cell differentiation;GO:0010906//regulation of glucose metabolic process;GO:0044267//cellular protein metabolic process;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway,GO:0031994//insulin-like growth factor I binding;GO:0005515//protein binding;GO:0001968//fibronectin binding,K10138//Transcriptional misregulation in cancer;p53 signaling pathway
348801,0,2,0,9,25,0,0,0,52,0,56,0,LNP1;leukemia NUP98 fusion partner 1,-,-,-,-
348807,0,0,0,0,0,0,0,0,18,0,7,0,CCDC37;coiled-coil domain containing 37,-,-,-,-
348825,0,0,0,0,0,0,17,0,45,0,0,0,TPRXL;tetra-peptide repeat homeobox-like,-,-,-,-
348840,0,0,0,0,0,0,0,0,8,0,0,0,"ANKRD18DP;ankyrin repeat domain 18D, pseudogene",-,-,-,-
3489,0,0,0,0,0,0,0,0,0,0,10,0,IGFBP6;insulin-like growth factor binding protein 6,GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0001558//regulation of cell growth;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0044267//cellular protein metabolic process,GO:0031994//insulin-like growth factor I binding,K10138//p53 signaling pathway;Transcriptional misregulation in cancer
348932,0,0,0,0,0,0,17,29,37,0,14,0,"SLC6A18;solute carrier family 6 (neutral amino acid transporter), member 18",GO:0005886//plasma membrane;GO:0031526//brush border membrane;GO:0005887//integral component of plasma membrane,GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport,GO:0005328//neurotransmitter:sodium symporter activity,-
348938,0,0,0,0,5,1,0,0,29,0,16,1,NIPAL4;NIPA-like domain containing 4,GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
348980,0,0,0,0,0,1,28,0,22,0,0,0,HCN1;hyperpolarization activated cyclic nucleotide-gated potassium channel 1,GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042391//regulation of membrane potential;GO:0046549//retinal cone cell development;GO:0071805//potassium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071320//cellular response to cAMP;GO:0006813//potassium ion transport;GO:0045176//apical protein localization,GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0042802//identical protein binding;GO:0030552//cAMP binding;GO:0005248//voltage-gated sodium channel activity,-
348995,0,63,0,22,1,0,0,0,15,147,8,158,NUP43;nucleoporin 43kDa,GO:0000777//condensed chromosome kinetochore;GO:0031080//nuclear pore outer ring;GO:0005829//cytosol;GO:0000776//kinetochore;GO:0005635//nuclear envelope,GO:0007059//chromosome segregation;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0007067//mitotic nuclear division;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport;GO:0005975//carbohydrate metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process,GO:0005515//protein binding,K14305//RNA transport
349075,0,0,0,6,12,0,0,0,68,0,6,472,ZNF713;zinc finger protein 713,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
3491,0,0,0,0,0,0,18,0,16,0,2,0,"CYR61;cysteine-rich, angiogenic inducer, 61",GO:0031012//extracellular matrix;GO:0005576//extracellular region,"GO:0006935//chemotaxis;GO:0043065//positive regulation of apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0003181//atrioventricular valve morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003281//ventricular septum development;GO:0001649//osteoblast differentiation;GO:0061036//positive regulation of cartilage development;GO:0045860//positive regulation of protein kinase activity;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0033690//positive regulation of osteoblast proliferation;GO:0060591//chondroblast differentiation;GO:0008283//cell proliferation;GO:0010518//positive regulation of phospholipase activity;GO:0060716//labyrinthine layer blood vessel development;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009653//anatomical structure morphogenesis;GO:0060710//chorio-allantoic fusion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0044319//wound healing, spreading of cells;GO:0043066//negative regulation of apoptotic process;GO:0030335//positive regulation of cell migration;GO:0030198//extracellular matrix organization;GO:0001558//regulation of cell growth;GO:0060413//atrial septum morphogenesis;GO:0002041//intussusceptive angiogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0072593//reactive oxygen species metabolic process",GO:0008201//heparin binding;GO:0005178//integrin binding;GO:0005520//insulin-like growth factor binding;GO:0050840//extracellular matrix binding,-
349114,4,0,0,0,0,0,0,0,11,0,0,0,LINC00265;long intergenic non-protein coding RNA 265,-,-,-,-
349136,0,0,0,0,0,30,16,0,8,0,0,0,WDR86;WD repeat domain 86,-,-,-,K10260//Ubiquitin mediated proteolysis
349149,0,34,56,0,0,0,0,0,15,9,0,0,"GJC3;gap junction protein, gamma 3, 30.2kDa",GO:0016021//integral component of membrane;GO:0005922//connexon complex;GO:0043209//myelin sheath,GO:0007605//sensory perception of sound;GO:0042552//myelination;GO:0007154//cell communication,GO:0042803//protein homodimerization activity,-
349152,111,29,0,0,0,7,19,21,15,124,6,0,DPY19L2P2;DPY19L2 pseudogene 2,-,-,-,-
349334,0,1,0,0,0,0,0,0,1,0,0,0,FOXD4L4;forkhead box D4-like 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
349565,0,0,0,9,51,11,0,0,0,0,16,0,NMNAT3;nicotinamide nucleotide adenylyltransferase 3,GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0019674//NAD metabolic process;GO:0006766//vitamin metabolic process;GO:0009435//NAD biosynthetic process;GO:0009611//response to wounding;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0000309//nicotinamide-nucleotide adenylyltransferase activity;GO:0005524//ATP binding;GO:0004515//nicotinate-nucleotide adenylyltransferase activity,K06210//Metabolic pathways;Nicotinate and nicotinamide metabolism
349633,0,0,0,0,0,0,0,0,32,0,0,0,PLET1;placenta expressed transcript 1,GO:0009897//external side of plasma membrane;GO:0031225//anchored component of membrane;GO:0016324//apical plasma membrane,"GO:0001953//negative regulation of cell-matrix adhesion;GO:0030154//cell differentiation;GO:0030335//positive regulation of cell migration;GO:0035313//wound healing, spreading of epidermal cells",-,-
349667,0,0,0,0,0,0,19,0,5,0,0,0,RTN4RL2;reticulon 4 receptor-like 2,GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045121//membrane raft;GO:0046658//anchored component of plasma membrane;GO:0009986//cell surface,GO:0031103//axon regeneration,GO:0004872//receptor activity,K06260//ECM-receptor interaction;Hematopoietic cell lineage
35,0,0,1,0,0,23,16,38,0,0,0,0,"ACADS;acyl-CoA dehydrogenase, C-2 to C-3 short chain",GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion,GO:0042594//response to starvation;GO:0006635//fatty acid beta-oxidation;GO:0051384//response to glucocorticoid;GO:0044281//small molecule metabolic process;GO:0051289//protein homotetramerization;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046359//butyrate catabolic process;GO:0044255//cellular lipid metabolic process,GO:0050660//flavin adenine dinucleotide binding;GO:0004085//butyryl-CoA dehydrogenase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0000062//fatty-acyl-CoA binding,"K00248//Fatty acid metabolism;Geraniol degradation;Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;Metabolic pathways;Butanoate metabolism"
350,0,1,0,0,0,0,0,0,28,0,0,0,APOH;apolipoprotein H (beta-2-glycoprotein I),GO:0031012//extracellular matrix;GO:0034364//high-density lipoprotein particle;GO:0042627//chylomicron;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0034361//very-low-density lipoprotein particle;GO:0005615//extracellular space,"GO:0016525//negative regulation of angiogenesis;GO:0051917//regulation of fibrinolysis;GO:0034197//triglyceride transport;GO:0030194//positive regulation of blood coagulation;GO:0031639//plasminogen activation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0051006//positive regulation of lipoprotein lipase activity;GO:0007597//blood coagulation, intrinsic pathway;GO:0051918//negative regulation of fibrinolysis;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0006641//triglyceride metabolic process;GO:0010596//negative regulation of endothelial cell migration;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0030195//negative regulation of blood coagulation",GO:0001948//glycoprotein binding;GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0060230//lipoprotein lipase activator activity;GO:0005543//phospholipid binding,K06496//Malaria;Cell adhesion molecules (CAMs);Staphylococcus aureus infection;K04002//Complement and coagulation cascades;Pertussis
350383,100,0,0,0,0,0,14,0,0,0,11,0,GPR142;G protein-coupled receptor 142,GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
3508,0,0,0,10,2,12,0,0,19,0,7,0,IGHMBP2;immunoglobulin mu binding protein 2,GO:0005634//nucleus;GO:0032797//SMN complex;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0030424//axon,"GO:0006412//translation;GO:0006351//transcription, DNA-templated;GO:0006260//DNA replication;GO:0032508//DNA duplex unwinding;GO:0008219//cell death;GO:0051260//protein homooligomerization;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006310//DNA recombination;GO:0006200//ATP catabolic process",GO:0003723//RNA binding;GO:0000049//tRNA binding;GO:0005524//ATP binding;GO:0003697//single-stranded DNA binding;GO:0003678//DNA helicase activity;GO:0008186//RNA-dependent ATPase activity;GO:0003677//DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0043022//ribosome binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0043141//ATP-dependent 5'-3' DNA helicase activity;GO:0032575//ATP-dependent 5'-3' RNA helicase activity,K14326//mRNA surveillance pathway;RNA transport
351,0,4,0,12,1,38,20,8,37,0,35,0,APP;amyloid beta (A4) precursor protein,GO:0030424//axon;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0031594//neuromuscular junction;GO:0005768//endosome;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0005641//nuclear envelope lumen;GO:0051233//spindle midzone;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0005911//cell-cell junction;GO:0005905//coated pit;GO:0031093//platelet alpha granule lumen;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0043235//receptor complex;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0043198//dendritic shaft;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0030134//ER to Golgi transport vesicle;GO:0035253//ciliary rootlet;GO:0045177//apical part of cell,"GO:0051563//smooth endoplasmic reticulum calcium ion homeostasis;GO:0030198//extracellular matrix organization;GO:0007409//axonogenesis;GO:0031175//neuron projection development;GO:0016322//neuron remodeling;GO:0051402//neuron apoptotic process;GO:0045665//negative regulation of neuron differentiation;GO:0008203//cholesterol metabolic process;GO:0050885//neuromuscular process controlling balance;GO:0008088//axon cargo transport;GO:0030900//forebrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006878//cellular copper ion homeostasis;GO:0043393//regulation of protein binding;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0007617//mating behavior;GO:0007219//Notch signaling pathway;GO:0001967//suckling behavior;GO:0006468//protein phosphorylation;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0048669//collateral sprouting in absence of injury;GO:0045087//innate immune response;GO:0007626//locomotory behavior;GO:0045931//positive regulation of mitotic cell cycle;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0050803//regulation of synapse structure and activity;GO:0006417//regulation of translation;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0006378//mRNA polyadenylation;GO:0040014//regulation of multicellular organism growth;GO:0008542//visual learning;GO:0051124//synaptic growth at neuromuscular junction;GO:0008344//adult locomotory behavior;GO:0016358//dendrite development;GO:0030168//platelet activation;GO:0010951//negative regulation of endopeptidase activity;GO:0016199//axon midline choice point recognition;GO:0006897//endocytosis;GO:0007596//blood coagulation;GO:0006979//response to oxidative stress;GO:0010952//positive regulation of peptidase activity;GO:0002576//platelet degranulation;GO:0007155//cell adhesion",GO:0003677//DNA binding;GO:0033130//acetylcholine receptor binding;GO:0042802//identical protein binding;GO:0051425//PTB domain binding;GO:0016504//peptidase activator activity;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding;GO:0070851//growth factor receptor binding;GO:0046914//transition metal ion binding;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0005102//receptor binding,K04520//Alzheimer's disease;Serotonergic synapse
3512,0,0,0,0,0,0,27,0,74,0,0,0,"IGJ;immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides",GO:0071752//secretory dimeric IgA immunoglobulin complex;GO:0071757//hexameric IgM immunoglobulin complex;GO:0071756//pentameric IgM immunoglobulin complex;GO:0005615//extracellular space;GO:0071748//monomeric IgA immunoglobulin complex;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,GO:0060267//positive regulation of respiratory burst;GO:0045087//innate immune response;GO:0003094//glomerular filtration;GO:0032461//positive regulation of protein oligomerization;GO:0001895//retina homeostasis;GO:0002250//adaptive immune response;GO:0006955//immune response;GO:0019731//antibacterial humoral response,GO:0031210//phosphatidylcholine binding;GO:0019862//IgA binding;GO:0034987//immunoglobulin receptor binding;GO:0003823//antigen binding;GO:0042834//peptidoglycan binding;GO:0042803//protein homodimerization activity;GO:0003697//single-stranded DNA binding,-
3516,1,0,4,55,192,0,23,0,42,72,0,0,RBPJ;recombination signal binding protein for immunoglobulin kappa J region,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0002193//MAML1-RBP-Jkappa- ICN1 complex,"GO:0009912//auditory receptor cell fate commitment;GO:0048733//sebaceous gland development;GO:0060486//Clara cell differentiation;GO:0009957//epidermal cell fate specification;GO:0003214//cardiac left ventricle morphogenesis;GO:0060844//arterial endothelial cell fate commitment;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:1901186//positive regulation of ERBB signaling pathway;GO:0035019//somatic stem cell maintenance;GO:0006310//DNA recombination;GO:0035912//dorsal aorta morphogenesis;GO:0003160//endocardium morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0008285//negative regulation of cell proliferation;GO:0097101//blood vessel endothelial cell fate specification;GO:0010467//gene expression;GO:0042742//defense response to bacterium;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0060716//labyrinthine layer blood vessel development;GO:0002437//inflammatory response to antigenic stimulus;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0048820//hair follicle maturation;GO:0001525//angiogenesis;GO:0061314//Notch signaling involved in heart development;GO:0048505//regulation of timing of cell differentiation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0072602//interleukin-4 secretion;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030216//keratinocyte differentiation;GO:0006959//humoral immune response;GO:0007219//Notch signaling pathway;GO:0003139//secondary heart field specification;GO:1901189//positive regulation of ephrin receptor signaling pathway;GO:0030183//B cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1901297//positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0036302//atrioventricular canal development;GO:0072554//blood vessel lumenization;GO:0001837//epithelial to mesenchymal transition;GO:0021983//pituitary gland development;GO:0001974//blood vessel remodeling;GO:0030279//negative regulation of ossification",GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0047485//protein N-terminus binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000150//recombinase activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K06053//Notch signaling pathway;Epstein-Barr virus infection
352887,0,0,0,0,1,0,0,0,0,0,0,0,GYG2P1;glycogenin 2 pseudogene 1,-,-,-,-
352909,259,18,0,12,0,32,21,92,162,0,0,0,"DNAAF3;dynein, axonemal, assembly factor 3",GO:0005737//cytoplasm,GO:0070286//axonemal dynein complex assembly;GO:0044458//motile cilium assembly,-,-
352954,41,23,53,12,59,14,0,202,29,57,0,305,"GATS;GATS, stromal antigen 3 opposite strand",-,-,-,K13055//Oocyte meiosis
352961,0,0,0,0,0,0,1,0,0,0,0,0,HCG26;HLA complex group 26 (non-protein coding),-,-,-,-
352999,0,0,0,0,0,21,11,0,30,0,0,0,C6orf58;chromosome 6 open reading frame 58,GO:0070062//extracellular vesicular exosome,-,-,-
353,0,30,1,1,1,0,0,0,0,0,0,0,APRT;adenine phosphoribosyltransferase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0044209//AMP salvage;GO:0006144//purine nucleobase metabolic process;GO:0032869//cellular response to insulin stimulus;GO:0044281//small molecule metabolic process;GO:0006168//adenine salvage;GO:0043101//purine-containing compound salvage;GO:0007595//lactation;GO:0007625//grooming behavior,GO:0002055//adenine binding;GO:0003999//adenine phosphoribosyltransferase activity;GO:0016208//AMP binding,"K00759//Cysteine and methionine metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Butanoate metabolism;Purine metabolism;Citrate cycle (TCA cycle);Valine, leucine and isoleucine biosynthesis;Metabolic pathways;Pyruvate metabolism;Sulfur metabolism"
353088,0,0,0,2,0,0,0,0,0,0,1,0,ZNF429;zinc finger protein 429,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
353091,0,24,0,55,0,0,6,0,25,0,63,0,RAET1G;retinoic acid early transcript 1G,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0031225//anchored component of membrane,GO:0019882//antigen processing and presentation;GO:0042267//natural killer cell mediated cytotoxicity,GO:0046703//natural killer cell lectin-like receptor binding,K07987//Natural killer cell mediated cytotoxicity;K07986//Natural killer cell mediated cytotoxicity
353116,121,40,46,77,137,4,0,78,5,0,130,0,RILPL1;Rab interacting lysosomal protein-like 1,GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0072372//primary cilium;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:1901214//regulation of neuron death;GO:0006886//intracellular protein transport;GO:0003382//epithelial cell morphogenesis,-,K13883//Phagosome;Salmonella infection
353132,0,0,0,0,0,1,7,0,14,0,0,0,LCE1B;late cornified envelope 1B,-,GO:0031424//keratinization,-,-
353133,0,0,0,0,0,49,0,0,5,0,23,0,LCE1C;late cornified envelope 1C,-,GO:0031424//keratinization,-,-
353135,0,0,0,0,0,0,31,51,0,0,1,0,LCE1E;late cornified envelope 1E,-,GO:0031424//keratinization,-,-
353137,0,0,0,0,0,0,0,0,7,0,0,0,LCE1F;late cornified envelope 1F,-,GO:0031424//keratinization,-,-
353139,0,0,0,0,0,0,0,0,10,0,0,0,LCE2A;late cornified envelope 2A,-,GO:0031424//keratinization,-,-
353141,0,0,0,0,0,0,0,0,0,0,8,0,LCE2D;late cornified envelope 2D,-,GO:0031424//keratinization,-,-
353142,0,0,0,0,0,18,0,0,0,0,7,0,LCE3A;late cornified envelope 3A,-,GO:0031424//keratinization,-,-
353145,0,0,0,0,0,0,0,0,7,0,0,0,LCE3E;late cornified envelope 3E,-,GO:0031424//keratinization,-,-
353149,176,0,0,0,0,16,0,0,13,1,0,0,"TBC1D26;TBC1 domain family, member 26",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,-
353174,0,1043,816,994,2006,16,39,1646,213,5,3081,258,ZACN;zinc activated ligand-gated ion channel,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:0010043//response to zinc ion,GO:0015276//ligand-gated ion channel activity;GO:0008270//zinc ion binding;GO:0005230//extracellular ligand-gated ion channel activity,K04819//Serotonergic synapse
353189,158,1,0,0,0,0,0,0,75,3,7,0,"SLCO4C1;solute carrier organic anion transporter family, member 4C1",GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0043252//sodium-independent organic anion transport;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0055085//transmembrane transport;GO:0007283//spermatogenesis,GO:0005215//transporter activity,-
353219,0,0,0,24,63,0,0,0,16,0,15,0,KAAG1;kidney associated antigen 1,-,GO:0006955//immune response,-,-
353238,0,0,0,0,0,0,27,0,53,0,4,0,"PADI6;peptidyl arginine deiminase, type VI",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton,GO:0007010//cytoskeleton organization;GO:0018101//protein citrullination;GO:0007028//cytoplasm organization,GO:0004668//protein-arginine deiminase activity;GO:0005509//calcium ion binding,-
353274,89,28,0,5,49,0,33,0,17,92,21,1,ZNF445;zinc finger protein 445,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
353288,0,0,0,0,0,9,0,0,43,0,5,0,KRT26;keratin 26,GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
353299,0,0,0,0,0,13,0,0,54,0,14,0,RGSL1;regulator of G-protein signaling like 1,GO:0016021//integral component of membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway,-,-
353322,0,14,1,45,105,0,0,0,8,0,54,0,ANKRD37;ankyrin repeat domain 37,GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
353324,0,0,0,0,0,0,0,9,0,0,0,0,SPATA12;spermatogenesis associated 12,-,-,-,-
353333,0,0,0,0,0,0,0,0,0,0,6,0,KRTAP10-10;keratin associated protein 10-10,GO:0045095//keratin filament,-,-,-
353345,0,0,0,0,0,0,20,0,0,0,0,0,GPR141;G protein-coupled receptor 141,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
353355,50,29,0,23,35,18,44,0,60,0,12,0,ZNF233;zinc finger protein 233,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
353376,0,0,0,18,0,0,0,95,0,0,37,0,TICAM2;toll-like receptor adaptor molecule 2,GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005770//late endosome;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0031902//late endosome membrane;GO:0031901//early endosome membrane,GO:0002224//toll-like receptor signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:2000494//positive regulation of interleukin-18-mediated signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0071222//cellular response to lipopolysaccharide;GO:0070671//response to interleukin-12,GO:0005543//phospholipid binding;GO:0004871//signal transducer activity,K05409//Pertussis;Toll-like receptor signaling pathway;NF-kappa B signaling pathway
353497,0,0,0,0,11,0,0,0,42,0,0,0,POLN;polymerase (DNA directed) nu,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0036297//interstrand cross-link repair;GO:0019985//translesion synthesis;GO:0000724//double-strand break repair via homologous recombination;GO:0006261//DNA-dependent DNA replication,GO:0003677//DNA binding;GO:0030332//cyclin binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding,-
353500,0,0,0,21,11,21,20,342,7,17,71,0,BMP8A;bone morphogenetic protein 8a,GO:0005615//extracellular space,GO:0001503//ossification;GO:2000505//regulation of energy homeostasis;GO:0030154//cell differentiation;GO:0002024//diet induced thermogenesis;GO:0051216//cartilage development;GO:0040007//growth;GO:0046676//negative regulation of insulin secretion,GO:0008083//growth factor activity;GO:0005125//cytokine activity,K04663//Hedgehog signaling pathway;Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
354,11,244,9,278,804,37,0,2,0,0,2,0,KLK3;kallikrein-related peptidase 3,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process;GO:0016525//negative regulation of angiogenesis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K01325//Endocrine and other factor-regulated calcium reabsorption;K01351//Pathways in cancer;Prostate cancer
3543,0,0,0,0,0,13,0,0,8,0,0,0,IGLL1;immunoglobulin lambda-like polypeptide 1,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0006955//immune response,-,K06554//Primary immunodeficiency
3547,1,0,0,0,0,4,0,0,14,0,7,0,"IGSF1;immunoglobulin superfamily, member 1",GO:0005576//extracellular region;GO:0016020//membrane;GO:0016021//integral component of membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction",GO:0005515//protein binding;GO:0015026//coreceptor activity;GO:0034711//inhibin binding;GO:0004872//receptor activity,K06512//B cell receptor signaling pathway;Osteoclast differentiation
3549,0,0,0,0,0,0,0,0,0,0,10,0,IHH;indian hedgehog,GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0006508//proteolysis;GO:0045453//bone resorption;GO:0045880//positive regulation of smoothened signaling pathway;GO:0061053//somite development;GO:0060323//head morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048745//smooth muscle tissue development;GO:0040008//regulation of growth;GO:0001947//heart looping;GO:0035264//multicellular organism growth;GO:0031016//pancreas development;GO:0009880//embryonic pattern specification;GO:0007267//cell-cell signaling;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0060220//camera-type eye photoreceptor cell fate commitment;GO:0001708//cell fate specification;GO:0001701//in utero embryonic development;GO:0006029//proteoglycan metabolic process;GO:0003406//retinal pigment epithelium development;GO:0030704//vitelline membrane formation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0048074//negative regulation of eye pigmentation;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0048557//embryonic digestive tract morphogenesis;GO:0072498//embryonic skeletal joint development;GO:0016539//intein-mediated protein splicing;GO:0001501//skeletal system development;GO:0060135//maternal process involved in female pregnancy;GO:0009968//negative regulation of signal transduction;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0001649//osteoblast differentiation;GO:0007224//smoothened signaling pathway;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0048596//embryonic camera-type eye morphogenesis;GO:0032355//response to estradiol;GO:0001569//patterning of blood vessels;GO:0035988//chondrocyte proliferation;GO:0046639//negative regulation of alpha-beta T cell differentiation;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0003382//epithelial cell morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048469//cell maturation;GO:0048666//neuron development;GO:0090136//epithelial cell-cell adhesion;GO:0051216//cartilage development,GO:0008233//peptidase activity;GO:0005509//calcium ion binding;GO:0005113//patched binding,K11989//Hedgehog signaling pathway
355,0,0,0,0,0,24,0,0,0,0,0,0,FAS;Fas cell surface death receptor,GO:0031264//death-inducing signaling complex;GO:0005634//nucleus;GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0045121//membrane raft,GO:0003014//renal system process;GO:0042981//regulation of apoptotic process;GO:0007165//signal transduction;GO:0006915//apoptotic process;GO:0097049//motor neuron apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0051260//protein homooligomerization;GO:0045060//negative thymic T cell selection;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071455//cellular response to hyperoxia;GO:0006927//transformed cell apoptotic process;GO:0051384//response to glucocorticoid;GO:0006925//inflammatory cell apoptotic process;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0050869//negative regulation of B cell activation;GO:0097527//necroptotic signaling pathway;GO:0045619//regulation of lymphocyte differentiation;GO:0002377//immunoglobulin production;GO:0007623//circadian rhythm;GO:0019724//B cell mediated immunity;GO:0097190//apoptotic signaling pathway;GO:0006461//protein complex assembly;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0009636//response to toxic substance;GO:0006924//activation-induced cell death of T cells;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0048536//spleen development;GO:0032464//positive regulation of protein homooligomerization;GO:0045637//regulation of myeloid cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0071285//cellular response to lithium ion,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004871//signal transducer activity;GO:0004872//receptor activity;GO:0019900//kinase binding,K04390//Apoptosis;Herpes simplex infection;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Allograft rejection;Pathways in cancer;Autoimmune thyroid disease;African trypanosomiasis;Influenza A;Graft-versus-host disease;Alzheimer's disease;p53 signaling pathway;Measles;Chagas disease (American trypanosomiasis);Type I diabetes mellitus
3550,0,20,0,36,56,0,62,1,2,0,0,0,"IK;IK cytokine, down-regulator of HLA II",GO:0005615//extracellular space;GO:0005634//nucleus,GO:0006955//immune response;GO:0007267//cell-cell signaling,GO:0005515//protein binding;GO:0042802//identical protein binding,-
3551,0,0,0,5,7,0,5,0,26,139,0,0,"IKBKB;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta",GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0008385//IkappaB kinase complex;GO:0005634//nucleus,"GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042501//serine phosphorylation of STAT protein;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0001782//B cell homeostasis;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:2001259//positive regulation of cation channel activity;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0010765//positive regulation of sodium ion transport;GO:0009615//response to virus;GO:0034146//toll-like receptor 5 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0007252//I-kappaB phosphorylation;GO:0034162//toll-like receptor 9 signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway",GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0097110//scaffold protein binding;GO:0008384//IkappaB kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K07209//Acute myeloid leukemia;HTLV-I infection;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;NOD-like receptor signaling pathway;Shigellosis;Hepatitis C;Neurotrophin signaling pathway;Cytosolic DNA-sensing pathway;Toxoplasmosis;Osteoclast differentiation;Adipocytokine signaling pathway;Insulin signaling pathway;Pancreatic cancer;NF-kappa B signaling pathway;Chemokine signaling pathway;Pathways in cancer;Influenza A;Small cell lung cancer;Toll-like receptor signaling pathway;Prostate cancer;Chronic myeloid leukemia;Apoptosis;T cell receptor signaling pathway;MAPK signaling pathway;Herpes simplex infection;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;Type II diabetes mellitus;RIG-I-like receptor signaling pathway
3552,2,0,0,0,0,0,0,0,19,0,0,0,"IL1A;interleukin 1, alpha",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005576//extracellular region,GO:0045766//positive regulation of angiogenesis;GO:0034605//cellular response to heat;GO:0001660//fever generation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0008283//cell proliferation;GO:0050715//positive regulation of cytokine secretion;GO:0006955//immune response;GO:0008285//negative regulation of cell proliferation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051781//positive regulation of cell division;GO:0046688//response to copper ion;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0006915//apoptotic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0045840//positive regulation of mitosis;GO:0019221//cytokine-mediated signaling pathway;GO:0035234//ectopic germ cell programmed cell death,GO:0005507//copper ion binding;GO:0005149//interleukin-1 receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding,K04383//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Graft-versus-host disease;Leishmaniasis;Apoptosis;Osteoclast differentiation;Prion diseases;MAPK signaling pathway;Measles;Salmonella infection;Rheumatoid arthritis;Influenza A;Type I diabetes mellitus;Tuberculosis;Pertussis
3553,0,0,0,0,0,0,0,0,27,0,0,0,"IL1B;interleukin 1, beta",GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005829//cytosol,"GO:0030730//sequestering of triglyceride;GO:0000165//MAPK cascade;GO:0000187//activation of MAPK activity;GO:0050796//regulation of insulin secretion;GO:0030593//neutrophil chemotaxis;GO:0002711//positive regulation of T cell mediated immunity;GO:0035690//cellular response to drug;GO:0060559//positive regulation of calcidiol 1-monooxygenase activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045766//positive regulation of angiogenesis;GO:0032729//positive regulation of interferon-gamma production;GO:0007267//cell-cell signaling;GO:0019221//cytokine-mediated signaling pathway;GO:0009743//response to carbohydrate;GO:0045833//negative regulation of lipid metabolic process;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0043407//negative regulation of MAP kinase activity;GO:0033129//positive regulation of histone phosphorylation;GO:0006915//apoptotic process;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0007165//signal transduction;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042102//positive regulation of T cell proliferation;GO:0032755//positive regulation of interleukin-6 production;GO:0046330//positive regulation of JNK cascade;GO:0071407//cellular response to organic cyclic compound;GO:0071310//cellular response to organic substance;GO:0050995//negative regulation of lipid catabolic process;GO:0070487//monocyte aggregation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0030213//hyaluronan biosynthetic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050996//positive regulation of lipid catabolic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0031622//positive regulation of fever generation;GO:0043491//protein kinase B signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0032757//positive regulation of interleukin-8 production;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035505//positive regulation of myosin light chain kinase activity;GO:0060355//positive regulation of cell adhesion molecule production;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0010829//negative regulation of glucose transport;GO:0046827//positive regulation of protein export from nucleus;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0051781//positive regulation of cell division;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0033198//response to ATP;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032611//interleukin-1 beta production;GO:0001660//fever generation;GO:0071260//cellular response to mechanical stimulus;GO:0014805//smooth muscle adaptation;GO:0007566//embryo implantation;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0008285//negative regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0035066//positive regulation of histone acetylation;GO:0006955//immune response;GO:0035234//ectopic germ cell programmed cell death;GO:0045840//positive regulation of mitosis;GO:0032308//positive regulation of prostaglandin secretion;GO:0070164//negative regulation of adiponectin secretion;GO:0046627//negative regulation of insulin receptor signaling pathway",GO:0005149//interleukin-1 receptor binding;GO:0005125//cytokine activity;GO:0019904//protein domain specific binding,K04519//Legionellosis;Type I diabetes mellitus;NOD-like receptor signaling pathway;Malaria;Chagas disease (American trypanosomiasis);Measles;Leishmaniasis;Graft-versus-host disease;Prion diseases;Osteoclast differentiation;Alzheimer's disease;Cytosolic DNA-sensing pathway;Pertussis;Tuberculosis;African trypanosomiasis;Influenza A;Toll-like receptor signaling pathway;Rheumatoid arthritis;NF-kappa B signaling pathway;Salmonella infection;Amoebiasis;Apoptosis;MAPK signaling pathway;Herpes simplex infection;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction
3554,69,153,18,138,496,9,0,0,52,0,12,0,"IL1R1;interleukin 1 receptor, type I",GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0009986//cell surface,GO:0070498//interleukin-1-mediated signaling pathway;GO:0070555//response to interleukin-1;GO:0050727//regulation of inflammatory response;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway,"GO:0002020//protease binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0004908//interleukin-1 receptor activity;GO:0004909//interleukin-1, Type I, activating receptor activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity",K04386//Amoebiasis;Osteoclast differentiation;Apoptosis;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;HTLV-I infection;NF-kappa B signaling pathway
3556,94,0,0,0,0,26,0,62,66,53,0,0,IL1RAP;interleukin 1 receptor accessory protein,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0042094//interleukin-2 biosynthetic process;GO:0006461//protein complex assembly;GO:0006955//immune response;GO:0006954//inflammatory response,GO:0004871//signal transducer activity;GO:0004908//interleukin-1 receptor activity,K04723//Cytokine-cytokine receptor interaction;Apoptosis
3557,0,0,0,0,0,0,0,0,23,0,13,0,IL1RN;interleukin 1 receptor antagonist,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0014050//negative regulation of glutamate secretion;GO:0002439//chronic inflammatory response to antigenic stimulus;GO:0043507//positive regulation of JUN kinase activity;GO:0019752//carboxylic acid metabolic process;GO:0030073//insulin secretion;GO:0010243//response to organonitrogen compound;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0007613//memory;GO:0032496//response to lipopolysaccharide;GO:0006953//acute-phase response;GO:0006955//immune response;GO:0030336//negative regulation of cell migration;GO:0043066//negative regulation of apoptotic process;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0001660//fever generation;GO:0006629//lipid metabolic process;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0045837//negative regulation of membrane potential;GO:0051384//response to glucocorticoid;GO:2000660//negative regulation of interleukin-1-mediated signaling pathway;GO:0070670//response to interleukin-4,"GO:0005152//interleukin-1 receptor antagonist activity;GO:0005151//interleukin-1, Type II receptor binding;GO:0005150//interleukin-1, Type I receptor binding;GO:0045353//interleukin-1 Type II receptor antagonist activity;GO:0045352//interleukin-1 Type I receptor antagonist activity;GO:0005149//interleukin-1 receptor binding",-
3559,0,0,0,0,0,8,0,0,12,0,4,0,"IL2RA;interleukin 2 receptor, alpha",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,GO:0050777//negative regulation of immune response;GO:0007219//Notch signaling pathway;GO:0042104//positive regulation of activated T cell proliferation;GO:0006924//activation-induced cell death of T cells;GO:0050687//negative regulation of defense response to virus;GO:0038110//interleukin-2-mediated signaling pathway;GO:0045582//positive regulation of T cell differentiation;GO:0050728//negative regulation of inflammatory response;GO:0008283//cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0002437//inflammatory response to antigenic stimulus;GO:0006955//immune response;GO:0007166//cell surface receptor signaling pathway;GO:0046013//regulation of T cell homeostatic proliferation;GO:0006915//apoptotic process,GO:0008144//drug binding;GO:0019976//interleukin-2 binding;GO:0004911//interleukin-2 receptor activity,K05068//Jak-STAT signaling pathway;HTLV-I infection;Hematopoietic cell lineage;Endocytosis;Cytokine-cytokine receptor interaction;Measles
356,0,0,0,0,0,16,0,0,0,0,0,0,"FASLG;Fas ligand (TNF superfamily, member 6)",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005901//caveola;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0060205//cytoplasmic membrane-bounded vesicle lumen;GO:0005887//integral component of plasma membrane,"GO:0046666//retinal cell programmed cell death;GO:0043065//positive regulation of apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0070848//response to growth factor;GO:0006915//apoptotic process;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0007165//signal transduction;GO:0070266//necroptotic process;GO:0016525//negative regulation of angiogenesis;GO:0097527//necroptotic signaling pathway;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070231//T cell apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0006955//immune response;GO:0032496//response to lipopolysaccharide;GO:0006925//inflammatory cell apoptotic process;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030644//cellular chloride ion homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0048388//endosomal lumen acidification",GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005102//receptor binding,K04389//African trypanosomiasis;Type I diabetes mellitus;Influenza A;Chagas disease (American trypanosomiasis);Pathways in cancer;Autoimmune thyroid disease;Measles;MAPK signaling pathway;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Apoptosis;Graft-versus-host disease;Cytokine-cytokine receptor interaction;Allograft rejection;Neurotrophin signaling pathway
3560,0,0,0,0,2,22,0,84,48,98,8,0,"IL2RB;interleukin 2 receptor, beta",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,GO:0043066//negative regulation of apoptotic process;GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0006461//protein complex assembly;GO:0038110//interleukin-2-mediated signaling pathway;GO:0016032//viral process,GO:0019976//interleukin-2 binding;GO:0004911//interleukin-2 receptor activity,K05069//Transcriptional misregulation in cancer;Measles;Endocytosis;HTLV-I infection;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3561,0,0,0,0,0,0,0,0,50,0,9,0,"IL2RG;interleukin 2 receptor, gamma",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0035771//interleukin-4-mediated signaling pathway;GO:0038111//interleukin-7-mediated signaling pathway;GO:0038110//interleukin-2-mediated signaling pathway;GO:0016032//viral process;GO:0006955//immune response,GO:0019982//interleukin-7 binding;GO:0004911//interleukin-2 receptor activity;GO:0019976//interleukin-2 binding;GO:0004917//interleukin-7 receptor activity;GO:0005515//protein binding;GO:0004913//interleukin-4 receptor activity,K05070//Measles;Jak-STAT signaling pathway;Endocytosis;HTLV-I infection;Cytokine-cytokine receptor interaction;Primary immunodeficiency
3562,0,0,0,0,0,0,0,51,4,0,0,0,IL3;interleukin 3,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell proliferation;GO:0007399//nervous system development;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0035162//embryonic hemopoiesis;GO:0045740//positive regulation of DNA replication;GO:0006955//immune response,GO:0005135//interleukin-3 receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity,K04736//Hematopoietic cell lineage;Fc epsilon RI signaling pathway;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;Apoptosis;Asthma;Transcriptional misregulation in cancer
3563,32,18,0,24,0,3,3,0,2,0,0,0,"IL3RA;interleukin 3 receptor, alpha (low affinity)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0036016//cellular response to interleukin-3;GO:0038156//interleukin-3-mediated signaling pathway,GO:0004912//interleukin-3 receptor activity,K04737//Apoptosis;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;K05066//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway;Pathways in cancer
3566,76,1,0,0,0,0,0,1,18,0,0,0,IL4R;interleukin 4 receptor,GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005615//extracellular space,GO:0042127//regulation of cell proliferation;GO:0090197//positive regulation of chemokine secretion;GO:0035771//interleukin-4-mediated signaling pathway;GO:0002532//production of molecular mediator involved in inflammatory response;GO:0042832//defense response to protozoan;GO:0007165//signal transduction;GO:0043032//positive regulation of macrophage activation;GO:0030728//ovulation;GO:0006955//immune response;GO:0035556//intracellular signal transduction;GO:0043627//response to estrogen;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0045630//positive regulation of T-helper 2 cell differentiation,GO:0004913//interleukin-4 receptor activity;GO:0005515//protein binding;GO:0005057//receptor signaling protein activity,K05071//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway
3568,0,0,0,0,7,28,0,0,86,0,1,0,"IL5RA;interleukin 5 receptor, alpha",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0038043//interleukin-5-mediated signaling pathway;GO:0007165//signal transduction;GO:0002437//inflammatory response to antigenic stimulus;GO:0008283//cell proliferation;GO:0032674//regulation of interleukin-5 production,GO:0005515//protein binding;GO:0004914//interleukin-5 receptor activity,K05067//Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3569,76,0,0,0,0,12,18,0,16,0,0,0,IL6;interleukin 6,GO:0009897//external side of plasma membrane;GO:0005896//interleukin-6 receptor complex;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0046677//response to antibiotic;GO:0050871//positive regulation of B cell activation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0043066//negative regulation of apoptotic process;GO:0072540//T-helper 17 cell lineage commitment;GO:0008285//negative regulation of cell proliferation;GO:0008360//regulation of cell shape;GO:1901215//negative regulation of neuron death;GO:0002675//positive regulation of acute inflammatory response;GO:0009409//response to cold;GO:2000676//positive regulation of type B pancreatic cell apoptotic process;GO:0030168//platelet activation;GO:0071222//cellular response to lipopolysaccharide;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0050830//defense response to Gram-positive bacterium;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0031018//endocrine pancreas development;GO:0046849//bone remodeling;GO:0048635//negative regulation of muscle organ development;GO:0002548//monocyte chemotaxis;GO:0031667//response to nutrient levels;GO:0032868//response to insulin;GO:0002384//hepatic immune response;GO:0051384//response to glucocorticoid;GO:0032966//negative regulation of collagen biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031175//neuron projection development;GO:0006469//negative regulation of protein kinase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010888//negative regulation of lipid storage;GO:0050710//negative regulation of cytokine secretion;GO:0046427//positive regulation of JAK-STAT cascade;GO:0045599//negative regulation of fat cell differentiation;GO:0051024//positive regulation of immunoglobulin secretion;GO:0009408//response to heat;GO:0060445//branching involved in salivary gland morphogenesis;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0070102//interleukin-6-mediated signaling pathway;GO:0045765//regulation of angiogenesis;GO:0051607//defense response to virus;GO:0045454//cell redox homeostasis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045079//negative regulation of chemokine biosynthetic process;GO:0046888//negative regulation of hormone secretion;GO:0006959//humoral immune response;GO:0045721//negative regulation of gluconeogenesis;GO:0050829//defense response to Gram-negative bacterium;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0043410//positive regulation of MAPK cascade;GO:0016049//cell growth;GO:0032722//positive regulation of chemokine production;GO:0050679//positive regulation of epithelial cell proliferation;GO:0070091//glucagon secretion;GO:0051602//response to electrical stimulus;GO:0032494//response to peptidoglycan;GO:0045666//positive regulation of neuron differentiation;GO:0051971//positive regulation of transmission of nerve impulse;GO:0007568//aging;GO:0051592//response to calcium ion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045669//positive regulation of osteoblast differentiation;GO:0042832//defense response to protozoan;GO:2000366//positive regulation of STAT protein import into nucleus;GO:0042493//response to drug;GO:0010574//regulation of vascular endothelial growth factor production;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0070301//cellular response to hydrogen peroxide;GO:0006953//acute-phase response;GO:0002446//neutrophil mediated immunity;GO:0045727//positive regulation of translation;GO:0031000//response to caffeine;GO:0006954//inflammatory response;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0001781//neutrophil apoptotic process;GO:0019221//cytokine-mediated signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0009612//response to mechanical stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0046716//muscle cell cellular homeostasis;GO:0045740//positive regulation of DNA replication;GO:0045188//regulation of circadian sleep/wake cycle, non-REM sleep;GO:0043200//response to amino acid",GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005138//interleukin-6 receptor binding,K05405//Amoebiasis;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Herpes simplex infection;Influenza A;Intestinal immune network for IgA production;Toll-like receptor signaling pathway;African trypanosomiasis;Tuberculosis;Pertussis;Salmonella infection;Rheumatoid arthritis;Pathways in cancer;Measles;Cytosolic DNA-sensing pathway;Prion diseases;Graft-versus-host disease;Hypertrophic cardiomyopathy (HCM);NOD-like receptor signaling pathway;Legionellosis;Transcriptional misregulation in cancer;Jak-STAT signaling pathway;HTLV-I infection;Malaria;Chagas disease (American trypanosomiasis)
357,0,1,0,0,48,8,27,0,16,0,0,0,SHROOM2;shroom family member 2,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005913//cell-cell adherens junction;GO:0005856//cytoskeleton;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0031941//filamentous actin;GO:0005923//tight junction;GO:0005874//microtubule;GO:0030864//cortical actin cytoskeleton,GO:0000902//cell morphogenesis;GO:0008057//eye pigment granule organization;GO:0043482//cellular pigment accumulation;GO:0032438//melanosome organization;GO:0016477//cell migration;GO:0045176//apical protein localization;GO:0051017//actin filament bundle assembly;GO:0043583//ear development;GO:0030835//negative regulation of actin filament depolymerization;GO:0007420//brain development;GO:0035725//sodium ion transmembrane transport;GO:0048593//camera-type eye morphogenesis;GO:0045217//cell-cell junction maintenance;GO:0032401//establishment of melanosome localization;GO:0043010//camera-type eye development;GO:0002089//lens morphogenesis in camera-type eye,GO:0051015//actin filament binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0015280//ligand-gated sodium channel activity;GO:0008013//beta-catenin binding;GO:0019904//protein domain specific binding,K05868//Progesterone-mediated oocyte maturation;Cell cycle;p53 signaling pathway;Oocyte meiosis;HTLV-I infection;K00901//Metabolic pathways;Phosphatidylinositol signaling system;Glycerolipid metabolism;Glycerophospholipid metabolism
3570,113,0,0,0,0,0,15,0,53,0,0,0,IL6R;interleukin 6 receptor,GO:0005576//extracellular region;GO:0005896//interleukin-6 receptor complex;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0016324//apical plasma membrane,GO:0002548//monocyte chemotaxis;GO:0019221//cytokine-mediated signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010536//positive regulation of activation of Janus kinase activity;GO:0034097//response to cytokine;GO:0002446//neutrophil mediated immunity;GO:0032717//negative regulation of interleukin-8 production;GO:0070102//interleukin-6-mediated signaling pathway;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0032755//positive regulation of interleukin-6 production;GO:0031018//endocrine pancreas development;GO:0006953//acute-phase response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050829//defense response to Gram-negative bacterium;GO:0002384//hepatic immune response;GO:0045669//positive regulation of osteoblast differentiation;GO:0032966//negative regulation of collagen biosynthetic process;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043410//positive regulation of MAPK cascade;GO:0008284//positive regulation of cell proliferation;GO:0032722//positive regulation of chemokine production,GO:0019899//enzyme binding;GO:0070119//ciliary neurotrophic factor binding;GO:0004915//interleukin-6 receptor activity;GO:0005138//interleukin-6 receptor binding;GO:0019981//interleukin-6 binding;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K05055//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage
3572,0,39,45,33,87,20,0,0,15,6,16,0,IL6ST;interleukin 6 signal transducer,GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0070110//ciliary neurotrophic factor receptor complex;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0009897//external side of plasma membrane;GO:0005615//extracellular space;GO:0005900//oncostatin-M receptor complex;GO:0005896//interleukin-6 receptor complex,GO:0045669//positive regulation of osteoblast differentiation;GO:0038165//oncostatin-M-mediated signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0008593//regulation of Notch signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0070104//negative regulation of interleukin-6-mediated signaling pathway;GO:0002675//positive regulation of acute inflammatory response;GO:0038154//interleukin-11-mediated signaling pathway;GO:0070102//interleukin-6-mediated signaling pathway;GO:0002821//positive regulation of adaptive immune response;GO:0042102//positive regulation of T cell proliferation;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0016032//viral process;GO:0070106//interleukin-27-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0048711//positive regulation of astrocyte differentiation;GO:0005977//glycogen metabolic process;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0034097//response to cytokine,GO:0004924//oncostatin-M receptor activity;GO:0019838//growth factor binding;GO:0019981//interleukin-6 binding;GO:0045509//interleukin-27 receptor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004921//interleukin-11 receptor activity;GO:0019970//interleukin-11 binding;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0005127//ciliary neurotrophic factor receptor binding;GO:0004923//leukemia inhibitory factor receptor activity;GO:0005138//interleukin-6 receptor binding;GO:0004915//interleukin-6 receptor activity,K05060//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3574,0,25,0,2,0,0,0,0,18,0,0,0,IL7;interleukin 7,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0048873//homeostasis of number of cells within a tissue;GO:0043066//negative regulation of apoptotic process;GO:0045453//bone resorption;GO:0009887//organ morphogenesis;GO:0046622//positive regulation of organ growth;GO:0006959//humoral immune response;GO:0043086//negative regulation of catalytic activity;GO:0002360//T cell lineage commitment;GO:0010468//regulation of gene expression;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0030890//positive regulation of B cell proliferation;GO:0007267//cell-cell signaling;GO:0045582//positive regulation of T cell differentiation;GO:0008284//positive regulation of cell proliferation,GO:0008083//growth factor activity;GO:0005139//interleukin-7 receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding,K05431//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage
3575,0,0,0,0,0,33,0,0,13,0,0,0,IL7R;interleukin 7 receptor,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0006955//immune response;GO:0000018//regulation of DNA recombination;GO:0010628//positive regulation of gene expression;GO:0042100//B cell proliferation;GO:0008361//regulation of cell size;GO:0038111//interleukin-7-mediated signaling pathway;GO:0016049//cell growth;GO:0030217//T cell differentiation;GO:0048535//lymph node development;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0000902//cell morphogenesis;GO:0007166//cell surface receptor signaling pathway;GO:0048872//homeostasis of number of cells;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0002377//immunoglobulin production;GO:0007165//signal transduction,GO:0003823//antigen binding;GO:0005515//protein binding;GO:0004917//interleukin-7 receptor activity,K05072//Primary immunodeficiency;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3576,0,0,0,0,0,4,0,0,14,0,0,0,CXCL8;chemokine (C-X-C motif) ligand 8,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0071222//cellular response to lipopolysaccharide;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0071356//cellular response to tumor necrosis factor;GO:0007050//cell cycle arrest;GO:0007165//signal transduction;GO:0031623//receptor internalization;GO:0034976//response to endoplasmic reticulum stress;GO:0019722//calcium-mediated signaling;GO:0006954//inflammatory response;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0006928//cellular component movement;GO:0044267//cellular protein metabolic process;GO:0002237//response to molecule of bacterial origin;GO:0048566//embryonic digestive tract development;GO:0006935//chemotaxis;GO:0030155//regulation of cell adhesion;GO:0071347//cellular response to interleukin-1;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0001525//angiogenesis;GO:0035556//intracellular signal transduction;GO:0045091//regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050930//induction of positive chemotaxis;GO:0042119//neutrophil activation;GO:0030593//neutrophil chemotaxis;GO:0006955//immune response,GO:0005515//protein binding;GO:0005153//interleukin-8 receptor binding;GO:0008009//chemokine activity,K10030//Bladder cancer;Epithelial cell signaling in Helicobacter pylori infection;Amoebiasis;RIG-I-like receptor signaling pathway;Cytokine-cytokine receptor interaction;Pertussis;Influenza A;Toll-like receptor signaling pathway;Chemokine signaling pathway;Pathways in cancer;NF-kappa B signaling pathway;Rheumatoid arthritis;Salmonella infection;Hepatitis C;Transcriptional misregulation in cancer;Legionellosis;NOD-like receptor signaling pathway;Shigellosis;Malaria;Chagas disease (American trypanosomiasis)
3577,0,0,0,0,0,35,0,0,16,171,0,0,CXCR1;chemokine (C-X-C motif) receptor 1,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0002407//dendritic cell chemotaxis;GO:0006954//inflammatory response;GO:0031623//receptor internalization;GO:0006935//chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0038112//interleukin-8-mediated signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004918//interleukin-8 receptor activity;GO:0019959//interleukin-8 binding;GO:0004950//chemokine receptor activity,K04175//Epithelial cell signaling in Helicobacter pylori infection;Chemokine signaling pathway;Endocytosis;Cytokine-cytokine receptor interaction;K05050//Epithelial cell signaling in Helicobacter pylori infection;Cytokine-cytokine receptor interaction;Endocytosis;Chemokine signaling pathway
3579,84,0,0,0,0,0,62,0,51,0,0,0,CXCR2;chemokine (C-X-C motif) receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0009986//cell surface;GO:0016020//membrane;GO:0042629//mast cell granule,GO:0031623//receptor internalization;GO:0007165//signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0002407//dendritic cell chemotaxis;GO:0006954//inflammatory response;GO:0038112//interleukin-8-mediated signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0042119//neutrophil activation;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006968//cellular defense response;GO:0006935//chemotaxis;GO:0007166//cell surface receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway,GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0019959//interleukin-8 binding;GO:0004918//interleukin-8 receptor activity;GO:0016494//C-X-C chemokine receptor activity,K05050//Epithelial cell signaling in Helicobacter pylori infection;Endocytosis;Cytokine-cytokine receptor interaction;Chemokine signaling pathway
358,187,0,0,0,0,2,10,0,26,2,0,0,AQP1;aquaporin 1 (Colton blood group),GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045177//apical part of cell;GO:0020005//symbiont-containing vacuole membrane;GO:0031965//nuclear membrane;GO:0016324//apical plasma membrane;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0042383//sarcolemma;GO:0005903//brush border;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0005634//nucleus,GO:0042493//response to drug;GO:0050891//multicellular organismal water homeostasis;GO:0045766//positive regulation of angiogenesis;GO:0071456//cellular response to hypoxia;GO:0044281//small molecule metabolic process;GO:0070301//cellular response to hydrogen peroxide;GO:0006813//potassium ion transport;GO:0030157//pancreatic juice secretion;GO:0072488//ammonium transmembrane transport;GO:0034644//cellular response to UV;GO:0042060//wound healing;GO:0033363//secretory granule organization;GO:0071280//cellular response to copper ion;GO:0055085//transmembrane transport;GO:0048593//camera-type eye morphogenesis;GO:0071805//potassium ion transmembrane transport;GO:0071732//cellular response to nitric oxide;GO:0003094//glomerular filtration;GO:0042476//odontogenesis;GO:0015793//glycerol transport;GO:0046878//positive regulation of saliva secretion;GO:0044241//lipid digestion;GO:0035377//transepithelial water transport;GO:0006833//water transport;GO:0010634//positive regulation of epithelial cell migration;GO:0071288//cellular response to mercury ion;GO:0015670//carbon dioxide transport;GO:0010592//positive regulation of lamellipodium assembly;GO:0071260//cellular response to mechanical stimulus;GO:0043627//response to estrogen;GO:0030185//nitric oxide transport;GO:0033326//cerebrospinal fluid secretion;GO:0051458//corticotropin secretion;GO:0006182//cGMP biosynthetic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030950//establishment or maintenance of actin cytoskeleton polarity;GO:0070295//renal water absorption;GO:0072239//metanephric glomerulus vasculature development;GO:0048146//positive regulation of fibroblast proliferation;GO:0042538//hyperosmotic salinity response;GO:0043066//negative regulation of apoptotic process;GO:0019233//sensory perception of pain;GO:0003097//renal water transport;GO:0019725//cellular homeostasis;GO:0071474//cellular hyperosmotic response;GO:0021670//lateral ventricle development;GO:0071320//cellular response to cAMP;GO:0035378//carbon dioxide transmembrane transport;GO:0071549//cellular response to dexamethasone stimulus;GO:0071300//cellular response to retinoic acid;GO:0033554//cellular response to stress;GO:0085018//maintenance of symbiont-containing vacuole by host;GO:0071472//cellular response to salt stress;GO:0015701//bicarbonate transport;GO:0006884//cell volume homeostasis,GO:0005372//water transmembrane transporter activity;GO:0046875//ephrin receptor binding;GO:0008519//ammonium transmembrane transporter activity;GO:0015168//glycerol transmembrane transporter activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005267//potassium channel activity;GO:0022857//transmembrane transporter activity;GO:0015079//potassium ion transmembrane transporter activity;GO:0015250//water channel activity;GO:0005515//protein binding;GO:0030184//nitric oxide transmembrane transporter activity;GO:0035379//carbon dioxide transmembrane transporter activity,K09864//Proximal tubule bicarbonate reclamation;Bile secretion
3580,84,0,0,0,0,0,0,0,0,0,0,0,CXCR2P1;chemokine (C-X-C motif) receptor 2 pseudogene 1,-,-,-,K05050//Chemokine signaling pathway;Cytokine-cytokine receptor interaction;Endocytosis;Epithelial cell signaling in Helicobacter pylori infection
3581,0,0,0,0,0,0,0,0,36,0,0,327,IL9R;interleukin 9 receptor,GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space,GO:0038113//interleukin-9-mediated signaling pathway;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0007165//signal transduction,GO:0019983//interleukin-9 binding;GO:0004919//interleukin-9 receptor activity,K05073//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway
3587,0,0,0,0,0,0,19,3,9,0,0,0,"IL10RA;interleukin 10 receptor, alpha",GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0032496//response to lipopolysaccharide,GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0004920//interleukin-10 receptor activity;GO:0004872//receptor activity;GO:0019969//interleukin-10 binding,K05134//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;Toxoplasmosis;Epstein-Barr virus infection;Tuberculosis
3588,0,0,0,0,0,20,0,0,33,0,7,0,"IL10RB;interleukin 10 receptor, beta",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0032002//interleukin-28 receptor complex,GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0006955//immune response;GO:0051607//defense response to virus;GO:0006954//inflammatory response,GO:0004872//receptor activity;GO:0004920//interleukin-10 receptor activity;GO:0005515//protein binding,K05135//Epstein-Barr virus infection;Tuberculosis;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;Toxoplasmosis
3589,0,0,0,19,0,0,0,0,24,0,0,0,IL11;interleukin 11,GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0008284//positive regulation of cell proliferation;GO:0030183//B cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0007267//cell-cell signaling;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0046888//negative regulation of hormone secretion;GO:0030219//megakaryocyte differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation,GO:0008083//growth factor activity;GO:0005142//interleukin-11 receptor binding;GO:0005125//cytokine activity,K05417//Rheumatoid arthritis;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Jak-STAT signaling pathway
359,0,29,0,0,0,0,21,63,28,0,0,0,AQP2;aquaporin 2 (collecting duct),GO:0055037//recycling endosome;GO:0070382//exocytic vesicle;GO:0005764//lysosome;GO:0005791//rough endoplasmic reticulum;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0030658//transport vesicle membrane;GO:0043234//protein complex;GO:0005802//trans-Golgi network;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0072205//metanephric collecting duct development;GO:0007565//female pregnancy;GO:0010226//response to lithium ion;GO:0055085//transmembrane transport;GO:0071280//cellular response to copper ion;GO:0009651//response to salt stress;GO:0051928//positive regulation of calcium ion transport;GO:0007588//excretion;GO:0042594//response to starvation;GO:0033762//response to glucagon;GO:0032496//response to lipopolysaccharide;GO:0006972//hyperosmotic response;GO:0006833//water transport;GO:0007568//aging;GO:0042631//cellular response to water deprivation;GO:0003097//renal water transport;GO:0015793//glycerol transport;GO:0051592//response to calcium ion;GO:0006884//cell volume homeostasis;GO:0006915//apoptotic process;GO:0071288//cellular response to mercury ion;GO:0030042//actin filament depolymerization,GO:0015250//water channel activity;GO:0015168//glycerol transmembrane transporter activity;GO:0005372//water transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0003779//actin binding,K09865//Vasopressin-regulated water reabsorption
3590,0,0,0,0,0,0,0,0,6,0,4,0,"IL11RA;interleukin 11 receptor, alpha",GO:0005887//integral component of plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0032502//developmental process;GO:0007566//embryo implantation;GO:0007165//signal transduction;GO:0060322//head development,GO:0004888//transmembrane signaling receptor activity;GO:0004871//signal transducer activity;GO:0004896//cytokine receptor activity,K00965//Hematopoietic cell lineage;Galactose metabolism;Cytokine-cytokine receptor interaction;Metabolic pathways;Jak-STAT signaling pathway;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;K05056//Jak-STAT signaling pathway;Metabolic pathways;Galactose metabolism;Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Amino sugar and nucleotide sugar metabolism
3592,0,0,0,0,0,8,0,0,1,0,0,0,IL12A;interleukin 12A,GO:0043514//interleukin-12 complex;GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0032816//positive regulation of natural killer cell activation;GO:0032700//negative regulation of interleukin-17 production;GO:0097191//extrinsic apoptotic signaling pathway;GO:0050671//positive regulation of lymphocyte proliferation;GO:0016477//cell migration;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0050830//defense response to Gram-positive bacterium;GO:0042102//positive regulation of T cell proliferation;GO:0045582//positive regulation of T cell differentiation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0045785//positive regulation of cell adhesion;GO:0007050//cell cycle arrest;GO:0042520//positive regulation of tyrosine phosphorylation of Stat4 protein;GO:0006955//immune response;GO:0051135//positive regulation of NK T cell activation;GO:0032496//response to lipopolysaccharide;GO:0010224//response to UV-B;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0009615//response to virus;GO:0032729//positive regulation of interferon-gamma production;GO:0032946//positive regulation of mononuclear cell proliferation;GO:0042832//defense response to protozoan,GO:0005143//interleukin-12 receptor binding;GO:0045513//interleukin-27 binding;GO:0042163//interleukin-12 beta subunit binding;GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0046982//protein heterodimerization activity,K05406//Toll-like receptor signaling pathway;Influenza A;Pertussis;African trypanosomiasis;Tuberculosis;Allograft rejection;Cytokine-cytokine receptor interaction;Herpes simplex infection;RIG-I-like receptor signaling pathway;Amoebiasis;Jak-STAT signaling pathway;Chagas disease (American trypanosomiasis);Malaria;Type I diabetes mellitus;Legionellosis;Toxoplasmosis;Leishmaniasis;Measles
3593,0,0,0,0,0,0,8,0,62,0,0,0,IL12B;interleukin 12B,GO:0005615//extracellular space;GO:0016020//membrane;GO:0070743//interleukin-23 complex;GO:0043514//interleukin-12 complex;GO:0005737//cytoplasm,GO:0032946//positive regulation of mononuclear cell proliferation;GO:0042088//T-helper 1 type immune response;GO:0042035//regulation of cytokine biosynthetic process;GO:0010535//positive regulation of activation of JAK2 kinase activity;GO:0032693//negative regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032819//positive regulation of natural killer cell proliferation;GO:0010224//response to UV-B;GO:0042095//interferon-gamma biosynthetic process;GO:0051135//positive regulation of NK T cell activation;GO:0002323//natural killer cell activation involved in immune response;GO:0019953//sexual reproduction;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0019233//sensory perception of pain;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0016477//cell migration;GO:0042520//positive regulation of tyrosine phosphorylation of Stat4 protein;GO:0007050//cell cycle arrest;GO:0071222//cellular response to lipopolysaccharide;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0032700//negative regulation of interleukin-17 production;GO:0032735//positive regulation of interleukin-12 production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0042510//regulation of tyrosine phosphorylation of Stat1 protein;GO:0050729//positive regulation of inflammatory response;GO:0050671//positive regulation of lymphocyte proliferation;GO:0030101//natural killer cell activation;GO:0002230//positive regulation of defense response to virus by host;GO:0044130//negative regulation of growth of symbiont in host;GO:0032729//positive regulation of interferon-gamma production;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0032760//positive regulation of tumor necrosis factor production;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0042832//defense response to protozoan;GO:0045672//positive regulation of osteoclast differentiation;GO:0034105//positive regulation of tissue remodeling;GO:0032733//positive regulation of interleukin-10 production;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0032740//positive regulation of interleukin-17 production;GO:0042093//T-helper cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0051607//defense response to virus;GO:0051142//positive regulation of NK T cell proliferation;GO:0045785//positive regulation of cell adhesion;GO:0043382//positive regulation of memory T cell differentiation;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0071346//cellular response to interferon-gamma;GO:0042104//positive regulation of activated T cell proliferation;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0032816//positive regulation of natural killer cell activation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0019221//cytokine-mediated signaling pathway,GO:0045519//interleukin-23 receptor binding;GO:0005143//interleukin-12 receptor binding;GO:0042802//identical protein binding;GO:0004896//cytokine receptor activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042164//interleukin-12 alpha subunit binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0008083//growth factor activity,K05425//Legionellosis;Type I diabetes mellitus;Chagas disease (American trypanosomiasis);Jak-STAT signaling pathway;Measles;Toxoplasmosis;Leishmaniasis;Pertussis;African trypanosomiasis;Tuberculosis;Influenza A;Toll-like receptor signaling pathway;Amoebiasis;RIG-I-like receptor signaling pathway;Herpes simplex infection;Allograft rejection;Cytokine-cytokine receptor interaction
3594,0,0,0,0,0,15,31,52,33,0,10,0,"IL12RB1;interleukin 12 receptor, beta 1",GO:0042022//interleukin-12 receptor complex;GO:0072536//interleukin-23 receptor complex;GO:0009897//external side of plasma membrane,GO:0002230//positive regulation of defense response to virus by host;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0007165//signal transduction;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0071346//cellular response to interferon-gamma;GO:0043382//positive regulation of memory T cell differentiation;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0032729//positive regulation of interferon-gamma production;GO:0035722//interleukin-12-mediated signaling pathway;GO:0038155//interleukin-23-mediated signaling pathway;GO:0001916//positive regulation of T cell mediated cytotoxicity,GO:0004896//cytokine receptor activity;GO:0005143//interleukin-12 receptor binding;GO:0042019//interleukin-23 binding;GO:0042020//interleukin-23 receptor activity;GO:0016517//interleukin-12 receptor activity,K05063//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
3595,96,0,0,0,0,20,21,0,34,0,9,0,"IL12RB2;interleukin 12 receptor, beta 2",GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0032496//response to lipopolysaccharide;GO:0008284//positive regulation of cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032609//interferon-gamma production,GO:0019901//protein kinase binding;GO:0004896//cytokine receptor activity,K05064//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
3596,0,0,0,0,0,0,0,0,63,0,0,0,IL13;interleukin 13,GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region,GO:0010155//regulation of proton transport;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030890//positive regulation of B cell proliferation;GO:0043032//positive regulation of macrophage activation;GO:0006955//immune response;GO:1901247//negative regulation of lung ciliated cell differentiation;GO:0032496//response to lipopolysaccharide;GO:0002639//positive regulation of immunoglobulin production;GO:0045471//response to ethanol;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0071345//cellular response to cytokine stimulus;GO:0050714//positive regulation of protein secretion;GO:0006954//inflammatory response;GO:0071635//negative regulation of transforming growth factor beta production;GO:0035094//response to nicotine;GO:0007165//signal transduction;GO:2000231//positive regulation of pancreatic stellate cell proliferation;GO:1901251//positive regulation of lung goblet cell differentiation;GO:0006928//cellular component movement;GO:0032723//positive regulation of connective tissue growth factor production;GO:0042526//positive regulation of tyrosine phosphorylation of Stat6 protein;GO:0071260//cellular response to mechanical stimulus,GO:0005144//interleukin-13 receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding,K05435//Cytokine-cytokine receptor interaction;Fc epsilon RI signaling pathway;Jak-STAT signaling pathway;Asthma;Measles
3597,60,1,0,2,0,0,20,0,51,0,0,0,"IL13RA1;interleukin 13 receptor, alpha 1",GO:0005898//interleukin-13 receptor complex;GO:0005886//plasma membrane,GO:0002639//positive regulation of immunoglobulin production;GO:0030890//positive regulation of B cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0035772//interleukin-13-mediated signaling pathway,GO:0016515//interleukin-13 receptor activity;GO:0005515//protein binding,K05076//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
359710,228,0,0,0,0,0,10,0,0,0,6,0,"BPIFB3;BPI fold containing family B, member 3",GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0045087//innate immune response,GO:0008289//lipid binding,K05399//Toll-like receptor signaling pathway;Tuberculosis;NF-kappa B signaling pathway;Salmonella infection
359845,0,0,0,5,12,0,3,0,52,0,0,0,"FAM101B;family with sequence similarity 101, member B",GO:0015629//actin cytoskeleton,GO:0001837//epithelial to mesenchymal transition;GO:0030036//actin cytoskeleton organization,GO:0031005//filamin binding,K14443//RNA degradation;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
359948,68,30,0,7,65,18,2,0,96,0,0,0,IRF2BP2;interferon regulatory factor 2 binding protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding,-
36,0,83,1,91,208,7,26,62,60,0,0,28,"ACADSB;acyl-CoA dehydrogenase, short/branched chain",GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006631//fatty acid metabolic process;GO:0055114//oxidation-reduction process;GO:0009083//branched-chain amino acid catabolic process,GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity,"K09478//Valine, leucine and isoleucine degradation;Metabolic pathways;Biosynthesis of secondary metabolites;Fatty acid metabolism"
360,0,0,0,0,1,9,8,0,28,0,0,0,AQP3;aquaporin 3 (Gill blood group),GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0042476//odontogenesis;GO:0033280//response to vitamin D;GO:0032526//response to retinoic acid;GO:0015793//glycerol transport;GO:0006833//water transport;GO:0070295//renal water absorption;GO:0007588//excretion;GO:0006810//transport;GO:0015840//urea transport;GO:0055085//transmembrane transport;GO:0002684//positive regulation of immune system process;GO:0051592//response to calcium ion;GO:0045616//regulation of keratinocyte differentiation,GO:0005215//transporter activity;GO:0015254//glycerol channel activity;GO:0015250//water channel activity,K09876//Vasopressin-regulated water reabsorption
3600,0,0,0,0,0,27,9,0,24,0,0,0,IL15;interleukin 15,GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0016020//membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0005615//extracellular space,GO:0050691//regulation of defense response to virus by host;GO:0014732//skeletal muscle atrophy;GO:0030212//hyaluronan metabolic process;GO:0045580//regulation of T cell differentiation;GO:0007165//signal transduction;GO:0007568//aging;GO:0050778//positive regulation of immune response;GO:0001779//natural killer cell differentiation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0006954//inflammatory response;GO:0032740//positive regulation of interleukin-17 production;GO:0042102//positive regulation of T cell proliferation;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048535//lymph node development;GO:0050729//positive regulation of inflammatory response;GO:0001866//NK T cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0071305//cellular response to vitamin D;GO:0048469//cell maturation;GO:0007267//cell-cell signaling;GO:0045062//extrathymic T cell selection;GO:0034105//positive regulation of tissue remodeling;GO:0006955//immune response;GO:0032819//positive regulation of natural killer cell proliferation,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005126//cytokine receptor binding,K05433//Intestinal immune network for IgA production;Herpes simplex infection;Jak-STAT signaling pathway;Rheumatoid arthritis;HTLV-I infection;Cytokine-cytokine receptor interaction
360023,36,4,1,47,146,0,0,0,63,0,15,305,ZBTB41;zinc finger and BTB domain containing 41,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
360030,5,0,0,0,0,23,0,0,1,0,0,0,NANOGNB;NANOG neighbor homeobox,GO:0005634//nucleus,-,GO:0003677//DNA binding,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
3601,0,0,0,0,0,8,0,0,19,1,5,0,"IL15RA;interleukin 15 receptor, alpha",GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005615//extracellular space;GO:0030659//cytoplasmic vesicle membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0008283//cell proliferation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0031667//response to nutrient levels;GO:0010977//negative regulation of neuron projection development;GO:0007259//JAK-STAT cascade;GO:0019221//cytokine-mediated signaling pathway;GO:0007165//signal transduction,GO:0004896//cytokine receptor activity;GO:0005515//protein binding;GO:0004871//signal transducer activity,K05074//Intestinal immune network for IgA production;HTLV-I infection;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
360132,0,0,0,0,0,0,3,119,0,0,2,0,FKBP9P1;FK506 binding protein 9 pseudogene 1,-,-,-,-
360200,0,94,0,25,95,23,3,248,43,160,139,1,"TMPRSS9;transmembrane protease, serine 9",GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis;GO:0031639//plasminogen activation,GO:0004252//serine-type endopeptidase activity,-
360203,0,0,0,0,0,0,0,0,43,0,0,0,GLT6D1;glycosyltransferase 6 domain containing 1,GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process,"GO:0016758//transferase activity, transferring hexosyl groups",K00743//Glycosphingolipid biosynthesis - lacto and neolacto series
360205,0,80,9,89,115,2,0,85,0,0,424,0,PRAC2;prostate cancer susceptibility candidate 2,-,-,-,-
360226,0,0,0,0,0,0,33,0,0,0,2,0,"PRSS41;protease, serine, 41",GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0043229//intracellular organelle,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
3603,157,0,6,14,14,0,42,0,79,0,15,0,IL16;interleukin 16,GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006955//immune response;GO:0050930//induction of positive chemotaxis;GO:0016032//viral process;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0030595//leukocyte chemotaxis",GO:0005125//cytokine activity,K06095//Tight junction
3604,0,0,0,0,0,6,16,0,55,0,0,0,"TNFRSF9;tumor necrosis factor receptor superfamily, member 9",GO:0005887//integral component of plasma membrane,GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation,GO:0004872//receptor activity,K05146//Cytokine-cytokine receptor interaction
3605,0,0,1,0,0,15,28,0,24,0,0,40,IL17A;interleukin 17A,GO:0009897//external side of plasma membrane;GO:0005615//extracellular space,GO:0006955//immune response;GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0045672//positive regulation of osteoclast differentiation;GO:0071347//cellular response to interleukin-1;GO:0006915//apoptotic process;GO:0072537//fibroblast activation;GO:0006486//protein glycosylation;GO:0008219//cell death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0032747//positive regulation of interleukin-23 production;GO:0007267//cell-cell signaling,GO:0005125//cytokine activity,K05489//Cytokine-cytokine receptor interaction;Rheumatoid arthritis
3607,0,0,3,15,26,35,0,0,60,0,0,0,FOXK2;forkhead box K2,GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000287//magnesium ion binding,-
3608,0,32,0,67,116,4,81,0,16,3,26,0,ILF2;interleukin enhancer binding factor 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006955//immune response",GO:0005524//ATP binding;GO:0003725//double-stranded RNA binding;GO:0003677//DNA binding;GO:0016740//transferase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
3609,3,1,0,7,76,15,20,0,67,2,28,0,"ILF3;interleukin enhancer binding factor 3, 90kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045071//negative regulation of viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051607//defense response to virus;GO:0006468//protein phosphorylation;GO:0017148//negative regulation of translation",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003725//double-stranded RNA binding;GO:0003677//DNA binding,-
361,45,0,0,0,33,0,47,0,1,0,0,0,AQP4;aquaporin 4,GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0030315//T-tubule;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane,GO:0009314//response to radiation;GO:0006810//transport;GO:0015670//carbon dioxide transport;GO:0071392//cellular response to estradiol stimulus;GO:0055085//transmembrane transport;GO:0042538//hyperosmotic salinity response;GO:0007565//female pregnancy;GO:0007605//sensory perception of sound;GO:0050891//multicellular organismal water homeostasis;GO:0051260//protein homooligomerization;GO:0051384//response to glucocorticoid;GO:0070295//renal water absorption;GO:0006833//water transport;GO:0071346//cellular response to interferon-gamma,GO:0005372//water transmembrane transporter activity;GO:0015288//porin activity;GO:0015250//water channel activity,K09866//Bile secretion;Vasopressin-regulated water reabsorption
3611,0,50,58,122,89,0,8,0,7,0,97,0,ILK;integrin-linked kinase,GO:0043025//neuronal cell body;GO:0030027//lamellipodium;GO:0043234//protein complex;GO:0043198//dendritic shaft;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0043034//costamere;GO:0043195//terminal bouton;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030017//sarcomere;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005730//nucleolus,"GO:0051897//positive regulation of protein kinase B signaling;GO:0008284//positive regulation of cell proliferation;GO:0043491//protein kinase B signaling;GO:0043206//extracellular fibril organization;GO:0008283//cell proliferation;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001954//positive regulation of cell-matrix adhesion;GO:0070527//platelet aggregation;GO:0045773//positive regulation of axon extension;GO:0043524//negative regulation of neuron apoptotic process;GO:0050775//positive regulation of dendrite morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007050//cell cycle arrest;GO:0021675//nerve development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0045663//positive regulation of myoblast differentiation;GO:0048812//neuron projection morphogenesis;GO:0042327//positive regulation of phosphorylation;GO:0010761//fibroblast migration;GO:0045669//positive regulation of osteoblast differentiation;GO:0043406//positive regulation of MAP kinase activity;GO:0032288//myelin assembly;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0022011//myelination in peripheral nervous system;GO:0014912//negative regulation of smooth muscle cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0034329//cell junction assembly;GO:0030335//positive regulation of cell migration;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0007229//integrin-mediated signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007160//cell-matrix adhesion;GO:0007569//cell aging;GO:0051291//protein heterooligomerization;GO:0006468//protein phosphorylation",GO:0004871//signal transducer activity;GO:0017124//SH3 domain binding;GO:0004674//protein serine/threonine kinase activity;GO:0019901//protein kinase binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005524//ATP binding,K06272//Focal adhesion;Bacterial invasion of epithelial cells;Endometrial cancer;PPAR signaling pathway
3612,0,31,0,7,46,1,0,0,91,0,0,0,IMPA1;inositol(myo)-1(or 4)-monophosphatase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006796//phosphate-containing compound metabolic process;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0006021//inositol biosynthetic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046854//phosphatidylinositol phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0006661//phosphatidylinositol biosynthetic process,GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0042803//protein homodimerization activity;GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0031403//lithium ion binding;GO:0000287//magnesium ion binding,K01092//Inositol phosphate metabolism;Biosynthesis of secondary metabolites;Streptomycin biosynthesis;Metabolic pathways;Phosphatidylinositol signaling system
3613,0,0,0,0,0,0,27,55,21,0,0,0,IMPA2;inositol(myo)-1(or 4)-monophosphatase 2,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0043647//inositol phosphate metabolic process;GO:0046855//inositol phosphate dephosphorylation;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process;GO:0006021//inositol biosynthetic process,GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0052833//inositol monophosphate 4-phosphatase activity;GO:0052832//inositol monophosphate 3-phosphatase activity,K01092//Metabolic pathways;Streptomycin biosynthesis;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Biosynthesis of secondary metabolites
3614,0,0,0,1,12,0,0,0,5,118,0,0,IMPDH1;IMP (inosine 5'-monophosphate) dehydrogenase 1,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0055114//oxidation-reduction process;GO:0046651//lymphocyte proliferation;GO:0006144//purine nucleobase metabolic process;GO:0006177//GMP biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process,GO:0003723//RNA binding;GO:0003938//IMP dehydrogenase activity;GO:0030554//adenyl nucleotide binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0046872//metal ion binding,K00088//Fructose and mannose metabolism;Terpenoid backbone biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Purine metabolism;Drug metabolism - other enzymes
3615,80,1,1,38,161,12,46,185,65,0,73,0,IMPDH2;IMP (inosine 5'-monophosphate) dehydrogenase 2,GO:0070062//extracellular vesicular exosome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0006177//GMP biosynthetic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0046651//lymphocyte proliferation;GO:0071353//cellular response to interleukin-4;GO:0051289//protein homotetramerization;GO:0060041//retina development in camera-type eye;GO:0006144//purine nucleobase metabolic process;GO:0055114//oxidation-reduction process,GO:0003677//DNA binding;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0003938//IMP dehydrogenase activity;GO:0030554//adenyl nucleotide binding,K00088//Fructose and mannose metabolism;Terpenoid backbone biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Purine metabolism;Drug metabolism - other enzymes
3617,0,0,0,0,0,16,47,0,32,0,0,0,IMPG1;interphotoreceptor matrix proteoglycan 1,GO:0005578//proteinaceous extracellular matrix,GO:0007601//visual perception,GO:0005201//extracellular matrix structural constituent,-
3619,0,0,0,0,0,37,0,0,20,0,0,0,INCENP;inner centromere protein antigens 135/155kDa,"GO:0030496//midbody;GO:0005721//pericentric heterochromatin;GO:0000801//central element;GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0000800//lateral element;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0010369//chromocenter;GO:0005819//spindle;GO:0043234//protein complex",GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0000910//cytokinesis,GO:0005515//protein binding,-
362,0,0,0,0,0,0,0,0,25,0,0,0,AQP5;aquaporin 5,GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005902//microvillus,GO:0055085//transmembrane transport;GO:0048593//camera-type eye morphogenesis;GO:0007588//excretion;GO:0046541//saliva secretion;GO:0015670//carbon dioxide transport;GO:0030157//pancreatic juice secretion;GO:0006833//water transport;GO:0042476//odontogenesis,GO:0015250//water channel activity;GO:0005515//protein binding,K09867//Salivary secretion
3620,0,0,0,0,0,18,0,0,18,0,15,0,"IDO1;indoleamine 2,3-dioxygenase 1",GO:0030485//smooth muscle contractile fiber;GO:0005829//cytosol;GO:0032421//stereocilium bundle,GO:0034276//kynurenic acid biosynthetic process;GO:0002678//positive regulation of chronic inflammatory response;GO:0036269//swimming behavior;GO:0034641//cellular nitrogen compound metabolic process;GO:0002830//positive regulation of type 2 immune response;GO:0033555//multicellular organismal response to stress;GO:0043065//positive regulation of apoptotic process;GO:0002534//cytokine production involved in inflammatory response;GO:0032735//positive regulation of interleukin-12 production;GO:0055114//oxidation-reduction process;GO:0002666//positive regulation of T cell tolerance induction;GO:0044281//small molecule metabolic process;GO:0032693//negative regulation of interleukin-10 production;GO:0006569//tryptophan catabolic process;GO:0046007//negative regulation of activated T cell proliferation;GO:0007565//female pregnancy;GO:0019441//tryptophan catabolic process to kynurenine;GO:0070233//negative regulation of T cell apoptotic process;GO:0032496//response to lipopolysaccharide,"GO:0020037//heme binding;GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0046872//metal ion binding;GO:0009055//electron carrier activity;GO:0033754//indoleamine 2,3-dioxygenase activity",K00463//Tryptophan metabolism;African trypanosomiasis;Metabolic pathways
3621,0,1,53,0,46,0,0,1,68,0,36,0,"ING1;inhibitor of growth family, member 1",GO:0005634//nucleus,"GO:0006606//protein import into nucleus;GO:0010941//regulation of cell death;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth;GO:0016568//chromatin modification;GO:0007049//cell cycle;GO:0008285//negative regulation of cell proliferation",GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding,-
3622,0,0,0,0,34,0,0,36,3,0,0,0,"ING2;inhibitor of growth family, member 2",GO:0016602//CCAAT-binding factor complex;GO:0016580//Sin3 complex;GO:0005634//nucleus,"GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0040008//regulation of growth;GO:2000772//regulation of cellular senescence;GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0072520//seminiferous tubule development;GO:0030317//sperm motility;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007141//male meiosis I;GO:2001020//regulation of response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0007286//spermatid development;GO:0048133//male germ-line stem cell asymmetric division;GO:0016568//chromatin modification;GO:0007165//signal transduction",GO:0032403//protein complex binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
3623,0,0,0,0,0,0,0,3,21,0,1,0,"INHA;inhibin, alpha",GO:0005576//extracellular region;GO:0043512//inhibin A complex;GO:0043025//neuronal cell body;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment,GO:0051726//regulation of cell cycle;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0007267//cell-cell signaling;GO:0030218//erythrocyte differentiation;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0007399//nervous system development;GO:0009605//response to external stimulus;GO:0008584//male gonad development;GO:0007166//cell surface receptor signaling pathway;GO:0001501//skeletal system development;GO:0045650//negative regulation of macrophage differentiation;GO:0001541//ovarian follicle development;GO:0042326//negative regulation of phosphorylation;GO:0007050//cell cycle arrest;GO:0007165//signal transduction;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0045578//negative regulation of B cell differentiation;GO:0045786//negative regulation of cell cycle;GO:0042127//regulation of cell proliferation;GO:0030154//cell differentiation;GO:0042541//hemoglobin biosynthetic process,GO:0005102//receptor binding;GO:0034711//inhibin binding;GO:0005179//hormone activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity,-
3624,4,0,0,0,0,8,0,14,21,0,0,0,"INHBA;inhibin, beta A",GO:0043512//inhibin A complex;GO:0043509//activin A complex;GO:0005576//extracellular region,"GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0032270//positive regulation of cellular protein metabolic process;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0048333//mesodermal cell differentiation;GO:0006952//defense response;GO:0001942//hair follicle development;GO:0061029//eyelid development in camera-type eye;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0030308//negative regulation of cell growth;GO:0042701//progesterone secretion;GO:0008285//negative regulation of cell proliferation;GO:0060021//palate development;GO:0045648//positive regulation of erythrocyte differentiation;GO:0045578//negative regulation of B cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007050//cell cycle arrest;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045786//negative regulation of cell cycle;GO:0008584//male gonad development;GO:0040007//growth;GO:0045650//negative regulation of macrophage differentiation;GO:0007166//cell surface receptor signaling pathway;GO:0060279//positive regulation of ovulation;GO:0032924//activin receptor signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0042493//response to drug;GO:0030218//erythrocyte differentiation;GO:0007267//cell-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035987//endodermal cell differentiation;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0071397//cellular response to cholesterol;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0030154//cell differentiation;GO:0042476//odontogenesis;GO:0042541//hemoglobin biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007399//nervous system development;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0042326//negative regulation of phosphorylation;GO:0001541//ovarian follicle development",GO:0005179//hormone activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0070699//type II activin receptor binding;GO:0042802//identical protein binding;GO:0017046//peptide hormone binding,K04667//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
3625,0,0,0,9,0,0,21,0,10,0,2,1,"INHBB;inhibin, beta B",GO:0048471//perinuclear region of cytoplasm;GO:0005576//extracellular region,GO:0048599//oocyte development;GO:0032924//activin receptor signaling pathway;GO:0048178//negative regulation of hepatocyte growth factor biosynthetic process;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0006952//defense response;GO:0032869//cellular response to insulin stimulus;GO:0009267//cellular response to starvation;GO:0045444//fat cell differentiation;GO:0030154//cell differentiation;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0040007//growth;GO:0046676//negative regulation of insulin secretion;GO:0060279//positive regulation of ovulation;GO:0044320//cellular response to leptin stimulus;GO:0009612//response to mechanical stimulus;GO:0001541//ovarian follicle development,GO:0046789//host cell surface receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005179//hormone activity,K04667//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
3626,0,0,0,0,0,16,0,107,21,7,0,1,"INHBC;inhibin, beta C",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0040007//growth,GO:0005160//transforming growth factor beta receptor binding;GO:0008083//growth factor activity;GO:0005179//hormone activity,K04667//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
3627,0,0,0,0,0,0,0,0,27,210,11,0,CXCL10;chemokine (C-X-C motif) ligand 10,GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0030816//positive regulation of cAMP metabolic process;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0034605//cellular response to heat;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0007267//cell-cell signaling;GO:2000406//positive regulation of T cell migration;GO:0010996//response to auditory stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0009409//response to cold;GO:0010332//response to gamma radiation;GO:0045859//regulation of protein kinase activity;GO:0071222//cellular response to lipopolysaccharide;GO:0007165//signal transduction;GO:0008015//blood circulation;GO:0042127//regulation of cell proliferation;GO:0033280//response to vitamin D;GO:0051607//defense response to virus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0016525//negative regulation of angiogenesis;GO:0009306//protein secretion;GO:0007517//muscle organ development;GO:0006935//chemotaxis;GO:0010818//T cell chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway,GO:0005102//receptor binding;GO:0048248//CXCR3 chemokine receptor binding;GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0005515//protein binding,K12671//Cytokine-cytokine receptor interaction;Cytosolic DNA-sensing pathway;Chemokine signaling pathway;RIG-I-like receptor signaling pathway;Toll-like receptor signaling pathway;Influenza A
3628,58,42,0,0,3,0,0,0,39,0,6,0,INPP1;inositol polyphosphate-1-phosphatase,GO:0005829//cytosol,GO:0016311//dephosphorylation;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0007165//signal transduction;GO:0006796//phosphate-containing compound metabolic process,"GO:0004441//inositol-1,4-bisphosphate 1-phosphatase activity;GO:0052829//inositol-1,3,4-trisphosphate 1-phosphatase activity;GO:0046872//metal ion binding",K01107//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
363,2,0,0,0,0,0,3,0,0,0,24,0,"AQP6;aquaporin 6, kidney specific",GO:0005887//integral component of plasma membrane;GO:0030658//transport vesicle membrane,GO:0006833//water transport;GO:0055085//transmembrane transport;GO:0007588//excretion;GO:0042476//odontogenesis;GO:0006810//transport;GO:0006820//anion transport,GO:0015250//water channel activity;GO:0005253//anion channel activity,-
3630,0,0,0,0,0,8,0,0,13,0,0,0,INS;insulin,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0034774//secretory granule lumen;GO:0031904//endosome lumen;GO:0005788//endoplasmic reticulum lumen,"GO:0007267//cell-cell signaling;GO:0045861//negative regulation of proteolysis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006355//regulation of transcription, DNA-templated;GO:0033861//negative regulation of NAD(P)H oxidase activity;GO:0044281//small molecule metabolic process;GO:0002674//negative regulation of acute inflammatory response;GO:0006953//acute-phase response;GO:0015758//glucose transport;GO:0046631//alpha-beta T cell activation;GO:0000165//MAPK cascade;GO:0042060//wound healing;GO:0050796//regulation of insulin secretion;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0045922//negative regulation of fatty acid metabolic process;GO:0006006//glucose metabolic process;GO:0045909//positive regulation of vasodilation;GO:2000252//negative regulation of feeding behavior;GO:0050708//regulation of protein secretion;GO:0031954//positive regulation of protein autophosphorylation;GO:0045740//positive regulation of DNA replication;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0045721//negative regulation of gluconeogenesis;GO:0045597//positive regulation of cell differentiation;GO:0055089//fatty acid homeostasis;GO:0046889//positive regulation of lipid biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0050709//negative regulation of protein secretion;GO:0042177//negative regulation of protein catabolic process;GO:0090336//positive regulation of brown fat cell differentiation;GO:0042593//glucose homeostasis;GO:0051897//positive regulation of protein kinase B signaling;GO:0032880//regulation of protein localization;GO:0008284//positive regulation of cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0032270//positive regulation of cellular protein metabolic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0032460//negative regulation of protein oligomerization;GO:0060267//positive regulation of respiratory burst;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0030307//positive regulation of cell growth;GO:0050715//positive regulation of cytokine secretion;GO:0006521//regulation of cellular amino acid metabolic process;GO:0045818//negative regulation of glycogen catabolic process;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0050995//negative regulation of lipid catabolic process;GO:0045821//positive regulation of glycolytic process;GO:0090277//positive regulation of peptide hormone secretion;GO:0031018//endocrine pancreas development;GO:0032148//activation of protein kinase B activity;GO:0022898//regulation of transmembrane transporter activity;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0045908//negative regulation of vasodilation;GO:0045840//positive regulation of mitosis;GO:0006112//energy reserve metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling",GO:0002020//protease binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0005179//hormone activity;GO:0042802//identical protein binding,K04526//Aldosterone-regulated sodium reabsorption;Prostate cancer;Progesterone-mediated oocyte maturation;Type I diabetes mellitus;Regulation of autophagy;Insulin signaling pathway;Maturity onset diabetes of the young;Type II diabetes mellitus;Regulation of actin cytoskeleton;mTOR signaling pathway;Oocyte meiosis
3631,49,0,1,0,31,36,62,0,50,0,3,1,"INPP4A;inositol polyphosphate-4-phosphatase, type I, 107kDa",GO:0005829//cytosol,GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0006644//phospholipid metabolic process;GO:0016311//dephosphorylation,"GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity;GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity",K01109//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
3632,0,29,0,8,45,12,27,0,21,0,23,0,"INPP5A;inositol polyphosphate-5-phosphatase, 40kDa",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0046856//phosphatidylinositol dephosphorylation;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process,"GO:0042731//PH domain binding;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0005515//protein binding",K01106//Metabolic pathways;Insulin signaling pathway;Phosphatidylinositol signaling system;Inositol phosphate metabolism
3633,0,0,0,0,0,14,11,0,39,0,1,0,"INPP5B;inositol polyphosphate-5-phosphatase, 75kDa",GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton,GO:0007264//small GTPase mediated signal transduction;GO:0001701//in utero embryonic development;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0044281//small molecule metabolic process;GO:0070613//regulation of protein processing;GO:0030317//sperm motility;GO:0043647//inositol phosphate metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0007283//spermatogenesis,"GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",K01099//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
3635,68,15,0,0,1,18,64,0,3,123,15,0,"INPP5D;inositol polyphosphate-5-phosphatase, 145kDa",GO:0005829//cytosol;GO:0016020//membrane,GO:0007596//blood coagulation;GO:0045659//negative regulation of neutrophil differentiation;GO:0006915//apoptotic process;GO:0045671//negative regulation of osteoclast differentiation;GO:0043065//positive regulation of apoptotic process;GO:0008340//determination of adult lifespan;GO:0009968//negative regulation of signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0043647//inositol phosphate metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0030889//negative regulation of B cell proliferation;GO:0045779//negative regulation of bone resorption;GO:0050777//negative regulation of immune response;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0045579//positive regulation of B cell differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0035556//intracellular signal transduction;GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0045656//negative regulation of monocyte differentiation;GO:0016064//immunoglobulin mediated immune response;GO:0006796//phosphate-containing compound metabolic process;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0051425//PTB domain binding;GO:0017124//SH3 domain binding;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity,K03084//B cell receptor signaling pathway;Inositol phosphate metabolism;Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Phosphatidylinositol signaling system
3636,0,0,0,2,59,0,4,1,32,0,5,0,INPPL1;inositol polyphosphate phosphatase-like 1,GO:0030175//filopodium;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0009791//post-embryonic development;GO:0006006//glucose metabolic process;GO:0002376//immune system process;GO:0097178//ruffle assembly;GO:0001958//endochondral ossification;GO:0006644//phospholipid metabolic process;GO:0007155//cell adhesion;GO:0007015//actin filament organization;GO:0043647//inositol phosphate metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006897//endocytosis;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0010629//negative regulation of gene expression;GO:0008285//negative regulation of cell proliferation,GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0016787//hydrolase activity;GO:0042169//SH2 domain binding;GO:0003779//actin binding,K15909//Insulin signaling pathway;Phosphatidylinositol signaling system;B cell receptor signaling pathway;Inositol phosphate metabolism;Fc gamma R-mediated phagocytosis
3638,0,28,8,79,249,0,2,0,14,1,14,279,INSIG1;insulin induced gene 1,GO:0032937//SREBP-SCAP-Insig complex;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,GO:0008283//cell proliferation;GO:0006695//cholesterol biosynthetic process;GO:0045599//negative regulation of fat cell differentiation;GO:0060363//cranial suture morphogenesis;GO:0008152//metabolic process;GO:0060021//palate development;GO:0006641//triglyceride metabolic process;GO:1901303//negative regulation of cargo loading into COPII-coated vesicle;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0010894//negative regulation of steroid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0032933//SREBP signaling pathway,GO:0005515//protein binding,-
364,0,0,0,0,0,29,0,0,0,0,0,0,AQP7;aquaporin 7,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0006833//water transport;GO:0007588//excretion;GO:0006091//generation of precursor metabolites and energy;GO:0015793//glycerol transport,GO:0015254//glycerol channel activity;GO:0015250//water channel activity,K08771//PPAR signaling pathway
3640,0,0,0,0,0,0,27,0,15,0,0,0,INSL3;insulin-like 3 (Leydig cell),GO:0048471//perinuclear region of cytoplasm;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0001556//oocyte maturation;GO:0008584//male gonad development;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007283//spermatogenesis;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0001701//in utero embryonic development;GO:0007267//cell-cell signaling;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0002020//protease binding;GO:0005158//insulin receptor binding;GO:0005102//receptor binding;GO:0001664//G-protein coupled receptor binding;GO:0005179//hormone activity,-
3642,0,0,0,0,0,0,0,63,35,109,0,0,INSM1;insulinoma-associated 1,GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0061104//adrenal chromaffin cell differentiation;GO:0006351//transcription, DNA-templated;GO:0001933//negative regulation of protein phosphorylation;GO:0003310//pancreatic A cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060290//transdifferentiation;GO:0008285//negative regulation of cell proliferation;GO:0003358//noradrenergic neuron development;GO:0071158//positive regulation of cell cycle arrest;GO:0003309//type B pancreatic cell differentiation;GO:0061549//sympathetic ganglion development;GO:0007049//cell cycle;GO:0010468//regulation of gene expression;GO:0043254//regulation of protein complex assembly;GO:0045597//positive regulation of cell differentiation;GO:0003323//type B pancreatic cell development;GO:0042421//norepinephrine biosynthetic process;GO:0031018//endocrine pancreas development;GO:2000179//positive regulation of neural precursor cell proliferation",GO:0001047//core promoter binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042826//histone deacetylase binding;GO:0030332//cyclin binding;GO:0046872//metal ion binding;GO:0031490//chromatin DNA binding,-
3643,5,0,115,21,8,12,7,68,75,0,0,0,INSR;insulin receptor,GO:0016020//membrane;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005899//insulin receptor complex;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005901//caveola,"GO:0071363//cellular response to growth factor stimulus;GO:0045740//positive regulation of DNA replication;GO:0045995//regulation of embryonic development;GO:0046777//protein autophosphorylation;GO:0005975//carbohydrate metabolic process;GO:0031017//exocrine pancreas development;GO:0030335//positive regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0019087//transformation of host cell by virus;GO:0008544//epidermis development;GO:0000187//activation of MAPK activity;GO:0051290//protein heterotetramerization;GO:0048639//positive regulation of developmental growth;GO:0006355//regulation of transcription, DNA-templated;GO:0030238//male sex determination;GO:0008286//insulin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0045840//positive regulation of mitosis;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0023014//signal transduction by phosphorylation;GO:0003007//heart morphogenesis;GO:0032148//activation of protein kinase B activity;GO:0045821//positive regulation of glycolytic process;GO:0032147//activation of protein kinase activity;GO:0046326//positive regulation of glucose import;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0032869//cellular response to insulin stimulus;GO:0060267//positive regulation of respiratory burst;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0043410//positive regulation of MAPK cascade;GO:0008284//positive regulation of cell proliferation;GO:0042593//glucose homeostasis;GO:0051897//positive regulation of protein kinase B signaling",GO:0005159//insulin-like growth factor receptor binding;GO:0005009//insulin-activated receptor activity;GO:0051425//PTB domain binding;GO:0031994//insulin-like growth factor I binding;GO:0005524//ATP binding;GO:0005525//GTP binding;GO:0043559//insulin binding;GO:0031995//insulin-like growth factor II binding;GO:0005515//protein binding;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043560//insulin receptor substrate binding;GO:0004713//protein tyrosine kinase activity,K04527//Insulin signaling pathway;Type II diabetes mellitus;Adherens junction;Aldosterone-regulated sodium reabsorption
3645,0,0,0,0,0,0,0,0,91,0,21,0,INSRR;insulin receptor-related receptor,GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0071469//cellular response to alkaline pH;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0046777//protein autophosphorylation;GO:0030238//male sex determination;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0043560//insulin receptor substrate binding,K05086//Regulation of actin cytoskeleton;Prostate cancer
3646,0,85,1,206,259,25,0,0,5,0,15,0,"EIF3E;eukaryotic translation initiation factor 3, subunit E",GO:0005634//nucleus;GO:0000785//chromatin;GO:0016605//PML body;GO:0005730//nucleolus;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex,"GO:0045947//negative regulation of translational initiation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006413//translational initiation;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0003743//translation initiation factor activity;GO:0047485//protein N-terminus binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K03250//RNA transport;Hepatitis C
3651,0,0,0,0,6,0,19,0,0,0,0,0,PDX1;pancreatic and duodenal homeobox 1,GO:0005634//nucleus;GO:0005829//cytosol,GO:0007417//central nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0060290//transdifferentiation;GO:0009887//organ morphogenesis;GO:0043388//positive regulation of DNA binding;GO:0010942//positive regulation of cell death;GO:0006091//generation of precursor metabolites and energy;GO:0001889//liver development;GO:0048565//digestive tract development;GO:0042593//glucose homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0010260//organ senescence;GO:0043201//response to leucine;GO:0007263//nitric oxide mediated signal transduction;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0070542//response to fatty acid;GO:0048863//stem cell differentiation;GO:0009611//response to wounding;GO:0010040//response to iron(II) ion;GO:0035094//response to nicotine;GO:0032024//positive regulation of insulin secretion;GO:0030073//insulin secretion;GO:0031018//endocrine pancreas development;GO:0007224//smoothened signaling pathway;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016331//morphogenesis of embryonic epithelium;GO:0051384//response to glucocorticoid;GO:0003309//type B pancreatic cell differentiation;GO:0051594//detection of glucose;GO:0031100//organ regeneration;GO:0042493//response to drug;GO:0034097//response to cytokine;GO:0010157//response to chlorate;GO:0006366//transcription from RNA polymerase II promoter;GO:0006006//glucose metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031017//exocrine pancreas development,GO:0032403//protein complex binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0001046//core promoter sequence-specific DNA binding,K07594//Maturity onset diabetes of the young;Type II diabetes mellitus
3652,0,23,0,1,61,0,0,41,1,0,1,0,IPP;intracisternal A particle-promoted polypeptide,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton,-,GO:0003779//actin binding,-
3654,126,40,0,1,47,13,0,24,7,0,0,0,IRAK1;interleukin-1 receptor-associated kinase 1,GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005811//lipid particle;GO:0005886//plasma membrane;GO:0045323//interleukin-1 receptor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071456//cellular response to hypoxia;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0016567//protein ubiquitination;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0070498//interleukin-1-mediated signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046777//protein autophosphorylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0045087//innate immune response;GO:0051259//protein oligomerization;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034146//toll-like receptor 5 signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032494//response to peptidoglycan;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034162//toll-like receptor 9 signaling pathway;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway",GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0004672//protein kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005149//interleukin-1 receptor binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K04730//Neurotrophin signaling pathway;Apoptosis;Leishmaniasis;Toxoplasmosis;Epstein-Barr virus infection;Measles;NF-kappa B signaling pathway;Chagas disease (American trypanosomiasis);Toll-like receptor signaling pathway;Tuberculosis;Pertussis
3655,0,0,1,21,39,16,0,0,32,0,6,0,"ITGA6;integrin, alpha 6",GO:0005913//cell-cell adherens junction;GO:0009986//cell surface;GO:0030175//filopodium;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0034676//integrin alpha6-beta4 complex;GO:0009925//basal plasma membrane;GO:0005604//basement membrane;GO:0030056//hemidesmosome;GO:0005925//focal adhesion,GO:0048565//digestive tract development;GO:0042327//positive regulation of phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0072001//renal system development;GO:0030198//extracellular matrix organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0033627//cell adhesion mediated by integrin;GO:0010668//ectodermal cell differentiation;GO:0035878//nail development;GO:0034329//cell junction assembly;GO:0071407//cellular response to organic cyclic compound;GO:0016337//single organismal cell-cell adhesion;GO:0043588//skin development;GO:0046847//filopodium assembly;GO:0007044//cell-substrate junction assembly;GO:0050900//leukocyte migration;GO:0007229//integrin-mediated signaling pathway;GO:0097186//amelogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031589//cell-substrate adhesion;GO:0031581//hemidesmosome assembly;GO:0022409//positive regulation of cell-cell adhesion;GO:0043065//positive regulation of apoptotic process;GO:0031668//cellular response to extracellular stimulus;GO:0050873//brown fat cell differentiation;GO:0007596//blood coagulation;GO:0007160//cell-matrix adhesion,GO:0043236//laminin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005178//integrin binding,K06485//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Dilated cardiomyopathy;Small cell lung cancer;Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Toxoplasmosis;Hematopoietic cell lineage;Regulation of actin cytoskeleton;ECM-receptor interaction;Focal adhesion
3656,0,0,0,0,4,33,20,55,12,0,1,0,IRAK2;interleukin-1 receptor-associated kinase 2,GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005886//plasma membrane,"GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0006954//inflammatory response;GO:0070555//response to interleukin-1;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0000187//activation of MAPK activity;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0001959//regulation of cytokine-mediated signaling pathway;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling",GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004672//protein kinase activity,K04731//Neurotrophin signaling pathway;Apoptosis;Tuberculosis
3658,0,72,0,47,244,31,37,0,45,0,1,0,IREB2;iron-responsive element binding protein 2,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0050892//intestinal absorption;GO:0006826//iron ion transport;GO:0034101//erythrocyte homeostasis;GO:0030316//osteoclast differentiation;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0010040//response to iron(II) ion;GO:0071456//cellular response to hypoxia;GO:0017148//negative regulation of translation;GO:0006879//cellular iron ion homeostasis;GO:0009791//post-embryonic development;GO:0007568//aging;GO:0032526//response to retinoic acid,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0030371//translation repressor activity;GO:0030350//iron-responsive element binding","K01681//Carbon fixation pathways in prokaryotes;Phenylalanine, tyrosine and tryptophan biosynthesis;Microbial metabolism in diverse environments;Citrate cycle (TCA cycle);Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Biosynthesis of secondary metabolites"
3659,2,18,0,16,0,0,0,0,30,0,67,0,IRF1;interferon regulatory factor 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0032481//positive regulation of type I interferon production;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0035458//cellular response to interferon-beta;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0032728//positive regulation of interferon-beta production;GO:0002819//regulation of adaptive immune response;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045088//regulation of innate immune response;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0007050//cell cycle arrest;GO:0006366//transcription from RNA polymerase II promoter;GO:0007596//blood coagulation;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000564//regulation of CD8-positive, alpha-beta T cell proliferation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0071260//cellular response to mechanical stimulus",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding,K09444//Hepatitis C;Pertussis
366,0,0,0,57,73,9,1,0,60,0,54,0,AQP9;aquaporin 9,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane,GO:0006810//transport;GO:0071320//cellular response to cAMP;GO:0030104//water homeostasis;GO:0006863//purine nucleobase transport;GO:0006970//response to osmotic stress;GO:0015793//glycerol transport;GO:0006833//water transport;GO:0046689//response to mercury ion;GO:0015837//amine transport;GO:0007588//excretion;GO:0006955//immune response;GO:0008152//metabolic process;GO:0015855//pyrimidine nucleobase transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0055085//transmembrane transport;GO:0015722//canalicular bile acid transport;GO:0010033//response to organic substance,GO:0015288//porin activity;GO:0005275//amine transmembrane transporter activity;GO:0015254//glycerol channel activity;GO:0005345//purine nucleobase transmembrane transporter activity;GO:0015250//water channel activity;GO:0005372//water transmembrane transporter activity;GO:0005350//pyrimidine nucleobase transmembrane transporter activity;GO:0046943//carboxylic acid transmembrane transporter activity,K09877//Bile secretion
3660,0,0,0,17,56,0,35,0,30,0,0,0,IRF2;interferon regulatory factor 2,GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0060333//interferon-gamma-mediated signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0007596//blood coagulation;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0060337//type I interferon signaling pathway",GO:0000975//regulatory region DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
3661,0,1,0,0,30,10,0,0,18,0,7,0,IRF3;interferon regulatory factor 3,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0032481//positive regulation of type I interferon production;GO:0045351//type I interferon biosynthetic process;GO:0045087//innate immune response;GO:0050689//negative regulation of defense response to virus by host;GO:0032728//positive regulation of interferon-beta production;GO:0032480//negative regulation of type I interferon production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032727//positive regulation of interferon-alpha production;GO:0043330//response to exogenous dsRNA;GO:0050715//positive regulation of cytokine secretion;GO:0002224//toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0039530//MDA-5 signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0071888//macrophage apoptotic process;GO:0045358//negative regulation of interferon-beta biosynthetic process;GO:0006915//apoptotic process;GO:0097300//programmed necrotic cell death;GO:0006366//transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0071359//cellular response to dsRNA,GO:0003712//transcription cofactor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K05411//Pertussis;Influenza A;Toll-like receptor signaling pathway;Measles;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Herpes simplex infection;Hepatitis C;Cytosolic DNA-sensing pathway
3662,0,0,0,0,0,1,0,2,13,0,0,0,IRF4;interferon regulatory factor 4,GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0000788//nuclear nucleosome,"GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045082//positive regulation of interleukin-10 biosynthetic process;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0045404//positive regulation of interleukin-4 biosynthetic process;GO:0018022//peptidyl-lysine methylation;GO:0043966//histone H3 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060337//type I interferon signaling pathway;GO:0043967//histone H4 acetylation;GO:0072540//T-helper 17 cell lineage commitment;GO:0042110//T cell activation;GO:0043388//positive regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0045622//regulation of T-helper cell differentiation;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0043011//myeloid dendritic cell differentiation;GO:0045368//positive regulation of interleukin-13 biosynthetic process;GO:0042832//defense response to protozoan;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0000975//regulatory region DNA binding;GO:0016279//protein-lysine N-methyltransferase activity,-
3663,0,0,0,0,1,23,42,0,0,0,0,0,IRF5;interferon regulatory factor 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0032494//response to peptidoglycan;GO:0032727//positive regulation of interferon-alpha production;GO:0006351//transcription, DNA-templated;GO:0032735//positive regulation of interleukin-12 production;GO:0032495//response to muramyl dipeptide;GO:0019221//cytokine-mediated signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0060333//interferon-gamma-mediated signaling pathway",GO:0000975//regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K09446//Toll-like receptor signaling pathway
3664,1,99,3,135,262,15,0,0,6,0,0,0,IRF6;interferon regulatory factor 6,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043616//keratinocyte proliferation;GO:0030216//keratinocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060337//type I interferon signaling pathway;GO:0007050//cell cycle arrest;GO:0048468//cell development;GO:0060644//mammary gland epithelial cell differentiation",GO:0000975//regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
3665,0,0,0,0,0,0,1,44,0,0,2,0,IRF7;interferon regulatory factor 7,GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045655//regulation of monocyte differentiation;GO:0050776//regulation of immune response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0039530//MDA-5 signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0032608//interferon-beta production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0034127//regulation of MyD88-independent toll-like receptor signaling pathway;GO:0032727//positive regulation of interferon-alpha production;GO:0019043//establishment of viral latency;GO:0016064//immunoglobulin mediated immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034124//regulation of MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:2000110//negative regulation of macrophage apoptotic process;GO:0032481//positive regulation of type I interferon production;GO:0045351//type I interferon biosynthetic process;GO:0009615//response to virus;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002819//regulation of adaptive immune response;GO:0002224//toll-like receptor signaling pathway",GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding,K09447//Hepatitis C;Cytosolic DNA-sensing pathway;Herpes simplex infection;Influenza A;Toll-like receptor signaling pathway;RIG-I-like receptor signaling pathway;Measles
3667,0,49,0,22,61,49,0,0,31,75,121,0,IRS1;insulin receptor substrate 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005901//caveola;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0036064//ciliary basal body;GO:0005899//insulin receptor complex;GO:0005737//cytoplasm,GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0042593//glucose homeostasis;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0043491//protein kinase B signaling;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0046326//positive regulation of glucose import;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0016042//lipid catabolic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0007165//signal transduction;GO:0010468//regulation of gene expression;GO:0034504//protein localization to nucleus;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0030879//mammary gland development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032868//response to insulin;GO:0010907//positive regulation of glucose metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0030335//positive regulation of cell migration;GO:0046628//positive regulation of insulin receptor signaling pathway,GO:0043548//phosphatidylinositol 3-kinase binding;GO:0042169//SH2 domain binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005515//protein binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0004871//signal transducer activity;GO:0005080//protein kinase C binding,K07187//Aldosterone-regulated sodium reabsorption;Type II diabetes mellitus;Adipocytokine signaling pathway;Insulin signaling pathway;Neurotrophin signaling pathway
3669,0,0,0,0,0,0,21,0,6,0,0,0,ISG20;interferon stimulated exonuclease gene 20kDa,GO:0005730//nucleolus;GO:0016605//PML body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0015030//Cajal body,"GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0008283//cell proliferation;GO:0045071//negative regulation of viral genome replication;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006401//RNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0006364//rRNA processing",GO:0030619//U1 snRNA binding;GO:0008859//exoribonuclease II activity;GO:0046872//metal ion binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0034511//U3 snoRNA binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0004527//exonuclease activity;GO:0030620//U2 snRNA binding,-
367,91,109,2,154,483,11,19,31,96,0,19,0,AR;androgen receptor,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm;GO:0043234//protein complex,"GO:0030850//prostate gland development;GO:0010467//gene expression;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0090003//regulation of establishment of protein localization to plasma membrane;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042327//positive regulation of phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0045720//negative regulation of integrin biosynthetic process;GO:0008219//cell death;GO:0008284//positive regulation of cell proliferation;GO:0051259//protein oligomerization;GO:0007267//cell-cell signaling;GO:0016049//cell growth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006810//transport;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0007548//sex differentiation;GO:0045726//positive regulation of integrin biosynthetic process;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005497//androgen binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0004882//androgen receptor activity;GO:0003677//DNA binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005102//receptor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0008013//beta-catenin binding,K08557//Pathways in cancer;Oocyte meiosis;Prostate cancer
3670,0,0,0,0,18,13,0,2,41,0,2,0,ISL1;ISL LIM homeobox 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0060413//atrial septum morphogenesis;GO:0048762//mesenchymal cell differentiation;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0021983//pituitary gland development;GO:0060037//pharyngeal system development;GO:0032729//positive regulation of interferon-gamma production;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0045766//positive regulation of angiogenesis;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0031103//axon regeneration;GO:0031016//pancreas development;GO:0045665//negative regulation of neuron differentiation;GO:0003139//secondary heart field specification;GO:0032755//positive regulation of interleukin-6 production;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021524//visceral motor neuron differentiation;GO:0050728//negative regulation of inflammatory response;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0031290//retinal ganglion cell axon guidance;GO:0048880//sensory system development;GO:0048665//neuron fate specification;GO:0008284//positive regulation of cell proliferation;GO:0003215//cardiac right ventricle morphogenesis;GO:0060913//cardiac cell fate determination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0021522//spinal cord motor neuron differentiation;GO:0043388//positive regulation of DNA binding;GO:0071385//cellular response to glucocorticoid stimulus;GO:0043524//negative regulation of neuron apoptotic process;GO:0021520//spinal cord motor neuron cell fate specification;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0003151//outflow tract morphogenesis;GO:0032024//positive regulation of insulin secretion;GO:0021559//trigeminal nerve development;GO:0090074//negative regulation of protein homodimerization activity;GO:0001755//neural crest cell migration;GO:0060384//innervation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0032735//positive regulation of interleukin-12 production,GO:0030331//estrogen receptor binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003682//chromatin binding;GO:0043425//bHLH transcription factor binding;GO:0008270//zinc ion binding;GO:0001102//RNA polymerase II activating transcription factor binding,-
3672,0,0,0,0,0,37,0,19,118,0,0,0,"ITGA1;integrin, alpha 1",GO:0043204//perikaryon;GO:0005925//focal adhesion;GO:0001669//acrosomal vesicle;GO:0045178//basal part of cell;GO:0008305//integrin complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0043005//neuron projection;GO:0045121//membrane raft,GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006936//muscle contraction;GO:0008285//negative regulation of cell proliferation;GO:0007411//axon guidance;GO:0045123//cellular extravasation;GO:0007596//blood coagulation;GO:0043525//positive regulation of neuron apoptotic process;GO:0030593//neutrophil chemotaxis;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0042311//vasodilation;GO:0007160//cell-matrix adhesion;GO:0000187//activation of MAPK activity,GO:0019903//protein phosphatase binding;GO:0005518//collagen binding;GO:0005178//integrin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K06480//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Hematopoietic cell lineage;ECM-receptor interaction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Focal adhesion
3673,31,36,0,31,6,13,14,42,90,0,19,0,"ITGA2;integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)",GO:0045178//basal part of cell;GO:0043679//axon terminus;GO:0008305//integrin complex;GO:0009279//cell outer membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0034666//integrin alpha2-beta1 complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005925//focal adhesion,"GO:0007411//axon guidance;GO:0006929//substrate-dependent cell migration;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0033591//response to L-ascorbic acid;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0030198//extracellular matrix organization;GO:0045987//positive regulation of smooth muscle contraction;GO:0042493//response to drug;GO:0014075//response to amine;GO:0030879//mammary gland development;GO:0001666//response to hypoxia;GO:0007160//cell-matrix adhesion;GO:0043589//skin morphogenesis;GO:0010634//positive regulation of epithelial cell migration;GO:0007229//integrin-mediated signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0045727//positive regulation of translation;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0032870//cellular response to hormone stimulus;GO:0006971//hypotonic response;GO:0009615//response to virus;GO:0031346//positive regulation of cell projection organization;GO:0033627//cell adhesion mediated by integrin;GO:0009887//organ morphogenesis;GO:0043388//positive regulation of DNA binding;GO:0032967//positive regulation of collagen biosynthetic process;GO:0070365//hepatocyte differentiation;GO:0008283//cell proliferation;GO:0048333//mesodermal cell differentiation;GO:0002687//positive regulation of leukocyte migration;GO:0014911//positive regulation of smooth muscle cell migration;GO:0033343//positive regulation of collagen binding;GO:0050927//positive regulation of positive chemotaxis;GO:0001894//tissue homeostasis;GO:0007155//cell adhesion;GO:0014850//response to muscle activity;GO:0050729//positive regulation of inflammatory response;GO:0007596//blood coagulation;GO:0045184//establishment of protein localization;GO:0031589//cell-substrate adhesion;GO:0051971//positive regulation of transmission of nerve impulse;GO:0014070//response to organic cyclic compound;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016032//viral process",GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0001618//virus receptor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0046982//protein heterodimerization activity,K06481//Phagosome;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Small cell lung cancer;Dilated cardiomyopathy;ECM-receptor interaction;Regulation of actin cytoskeleton;Hematopoietic cell lineage;Hypertrophic cardiomyopathy (HCM);Focal adhesion
3674,0,0,0,0,0,33,17,2,16,0,0,0,"ITGA2B;integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)",GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0031092//platelet alpha granule membrane;GO:0008305//integrin complex;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,GO:0030168//platelet activation;GO:0007229//integrin-mediated signaling pathway;GO:0002687//positive regulation of leukocyte migration;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0070527//platelet aggregation;GO:0002576//platelet degranulation;GO:0007411//axon guidance;GO:0007596//blood coagulation;GO:0007160//cell-matrix adhesion,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0050840//extracellular matrix binding;GO:0070051//fibrinogen binding,K06476//Dilated cardiomyopathy;Small cell lung cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Hematopoietic cell lineage;ECM-receptor interaction;Regulation of actin cytoskeleton
3675,106,0,0,0,0,18,25,3,81,109,2,0,"ITGA3;integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)",GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0043235//receptor complex;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane;GO:0030426//growth cone;GO:0008305//integrin complex;GO:0034667//integrin alpha3-beta1 complex;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0009986//cell surface;GO:0031527//filopodium membrane;GO:0071438//invadopodium membrane,GO:0010628//positive regulation of gene expression;GO:0010811//positive regulation of cell-substrate adhesion;GO:0043588//skin development;GO:0034698//response to gonadotropin;GO:0031345//negative regulation of cell projection organization;GO:0048333//mesodermal cell differentiation;GO:0007507//heart development;GO:0030198//extracellular matrix organization;GO:0030111//regulation of Wnt signaling pathway;GO:0042493//response to drug;GO:0030510//regulation of BMP signaling pathway;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0030324//lung development;GO:0007160//cell-matrix adhesion;GO:0060135//maternal process involved in female pregnancy;GO:0001764//neuron migration;GO:0007596//blood coagulation;GO:0010634//positive regulation of epithelial cell migration;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007613//memory;GO:0010976//positive regulation of neuron projection development,GO:0019904//protein domain specific binding;GO:0001948//glycoprotein binding;GO:0043236//laminin binding;GO:0005518//collagen binding;GO:0002020//protease binding;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0001968//fibronectin binding,K06482//Hypertrophic cardiomyopathy (HCM);ECM-receptor interaction;Regulation of actin cytoskeleton;Hematopoietic cell lineage;Focal adhesion;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;Small cell lung cancer
3676,21,0,0,0,0,0,23,0,47,0,0,0,"ITGA4;integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0009986//cell surface;GO:0005911//cell-cell junction,GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0050776//regulation of immune response;GO:0030183//B cell differentiation;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0090074//negative regulation of protein homodimerization activity;GO:0034113//heterotypic cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0072678//T cell migration;GO:0007596//blood coagulation;GO:0007159//leukocyte cell-cell adhesion;GO:0001974//blood vessel remodeling;GO:0007507//heart development;GO:0030198//extracellular matrix organization;GO:0050901//leukocyte tethering or rolling;GO:0043113//receptor clustering;GO:0035987//endodermal cell differentiation;GO:0060324//face development;GO:0060710//chorio-allantoic fusion,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0001968//fibronectin binding,K06483//Hematopoietic cell lineage;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Leishmaniasis;Focal adhesion;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration;Intestinal immune network for IgA production;Dilated cardiomyopathy
3678,34,1,0,0,1,12,66,84,50,0,4,0,"ITGA5;integrin, alpha 5 (fibronectin receptor, alpha polypeptide)",GO:0009986//cell surface;GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0045202//synapse;GO:0005737//cytoplasm;GO:0008305//integrin complex;GO:0005911//cell-cell junction;GO:0032587//ruffle membrane;GO:0005925//focal adhesion;GO:0071062//alphav-beta3 integrin-vitronectin complex,"GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007596//blood coagulation;GO:0034113//heterotypic cell-cell adhesion;GO:0007613//memory;GO:0050900//leukocyte migration;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0035313//wound healing, spreading of epidermal cells;GO:0007229//integrin-mediated signaling pathway;GO:0007044//cell-substrate junction assembly;GO:0016032//viral process;GO:0031589//cell-substrate adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0035987//endodermal cell differentiation;GO:0030335//positive regulation of cell migration;GO:0007411//axon guidance;GO:2000811//negative regulation of anoikis;GO:0001525//angiogenesis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007159//leukocyte cell-cell adhesion;GO:0033631//cell-cell adhesion mediated by integrin;GO:0030198//extracellular matrix organization",GO:0005154//epidermal growth factor receptor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0005178//integrin binding;GO:0046872//metal ion binding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0005515//protein binding,K06484//Focal adhesion;Hypertrophic cardiomyopathy (HCM);Hematopoietic cell lineage;Regulation of actin cytoskeleton;ECM-receptor interaction;Pertussis;Dilated cardiomyopathy;Shigellosis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Bacterial invasion of epithelial cells;Phagosome
3679,0,0,0,0,1,16,0,60,81,0,22,0,"ITGA7;integrin, alpha 7",GO:0034677//integrin alpha7-beta1 complex;GO:0005737//cytoplasm;GO:0031594//neuromuscular junction;GO:0005886//plasma membrane;GO:0042383//sarcolemma;GO:0005927//muscle tendon junction;GO:0009986//cell surface,GO:0007517//muscle organ development;GO:0035987//endodermal cell differentiation;GO:0008360//regulation of cell shape;GO:0007519//skeletal muscle tissue development;GO:0007160//cell-matrix adhesion;GO:0034113//heterotypic cell-cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0016477//cell migration;GO:0048514//blood vessel morphogenesis;GO:0030198//extracellular matrix organization,GO:0046982//protein heterodimerization activity;GO:0005178//integrin binding;GO:0046872//metal ion binding;GO:0043236//laminin binding,K06583//Dilated cardiomyopathy;Focal adhesion;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);ECM-receptor interaction;Regulation of actin cytoskeleton
368,0,0,0,4,0,36,69,0,23,1,36,642,"ABCC6;ATP-binding cassette, sub-family C (CFTR/MRP), member 6",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0007601//visual perception;GO:0006200//ATP catabolic process;GO:0042493//response to drug;GO:0006810//transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding;GO:0005215//transporter activity",K05669//ABC transporters
3680,72,55,0,18,131,9,0,0,9,0,100,0,"ITGA9;integrin, alpha 9",GO:0008305//integrin complex;GO:0034679//integrin alpha9-beta1 complex;GO:0009925//basal plasma membrane;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007411//axon guidance;GO:0030593//neutrophil chemotaxis;GO:0042060//wound healing;GO:0030198//extracellular matrix organization,GO:0005518//collagen binding;GO:0043236//laminin binding;GO:0046872//metal ion binding,K06585//Dilated cardiomyopathy;Focal adhesion;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Regulation of actin cytoskeleton;ECM-receptor interaction
3681,0,0,0,0,0,0,32,0,0,64,12,83,"ITGAD;integrin, alpha D",GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0008305//integrin complex,GO:0034113//heterotypic cell-cell adhesion;GO:0030198//extracellular matrix organization;GO:0050798//activated T cell proliferation;GO:0006955//immune response;GO:0007229//integrin-mediated signaling pathway,GO:0046872//metal ion binding,K06594//Regulation of actin cytoskeleton
3682,0,0,0,6,6,59,0,115,15,1,0,361,"ITGAE;integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)",GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0008305//integrin complex,GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization,GO:0046872//metal ion binding,K06524//Regulation of actin cytoskeleton
3683,100,0,11,12,14,0,3,75,86,120,12,0,"ITGAL;integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)",GO:0001772//immunological synapse;GO:0008305//integrin complex;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0022409//positive regulation of cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007596//blood coagulation;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0007229//integrin-mediated signaling pathway;GO:0050850//positive regulation of calcium-mediated signaling;GO:0006954//inflammatory response;GO:0042102//positive regulation of T cell proliferation;GO:0050776//regulation of immune response;GO:0002291//T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:0050798//activated T cell proliferation;GO:0007159//leukocyte cell-cell adhesion;GO:0030198//extracellular matrix organization;GO:0043113//receptor clustering,GO:0032403//protein complex binding;GO:0030369//ICAM-3 receptor activity;GO:0050839//cell adhesion molecule binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K05718//Epstein-Barr virus infection;Viral myocarditis;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Regulation of actin cytoskeleton;Staphylococcus aureus infection;Leukocyte transendothelial migration;Malaria;HTLV-I infection;Rheumatoid arthritis
3684,39,0,0,0,0,28,30,3,50,0,0,0,"ITGAM;integrin, alpha M (complement component 3 receptor 3 subunit)",GO:0008305//integrin complex;GO:0005634//nucleus;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0002523//leukocyte migration involved in inflammatory response;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007159//leukocyte cell-cell adhesion;GO:0045087//innate immune response;GO:0014005//microglia development;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0010668//ectodermal cell differentiation;GO:0045123//cellular extravasation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050798//activated T cell proliferation;GO:0002224//toll-like receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0007596//blood coagulation,GO:0008201//heparin binding;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0001948//glycoprotein binding;GO:0001846//opsonin binding;GO:0043395//heparan sulfate proteoglycan binding,K06461//Amoebiasis;Cell adhesion molecules (CAMs);Leishmaniasis;Hematopoietic cell lineage;Staphylococcus aureus infection;Regulation of actin cytoskeleton;Transcriptional misregulation in cancer;Legionellosis;Tuberculosis;Pertussis;Leukocyte transendothelial migration;Phagosome
3685,127,0,0,0,16,0,64,41,107,0,15,0,"ITGAV;integrin, alpha V",GO:0005887//integral component of plasma membrane;GO:0031258//lamellipodium membrane;GO:0005925//focal adhesion;GO:0031528//microvillus membrane;GO:0032587//ruffle membrane;GO:0008305//integrin complex;GO:0045335//phagocytic vesicle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0031527//filopodium membrane;GO:0009986//cell surface;GO:0035867//alphav-beta3 integrin-IGF-1-IGF1R complex;GO:0016020//membrane,"GO:0045715//negative regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0007155//cell adhesion;GO:2000536//negative regulation of entry of bacterium into host cell;GO:0050764//regulation of phagocytosis;GO:0070588//calcium ion transmembrane transport;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0046718//viral entry into host cell;GO:0050919//negative chemotaxis;GO:0007596//blood coagulation;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031589//cell-substrate adhesion;GO:0016477//cell migration;GO:0050748//negative regulation of lipoprotein metabolic process;GO:0009615//response to virus;GO:0033690//positive regulation of osteoblast proliferation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0001525//angiogenesis;GO:0016049//cell growth;GO:0008284//positive regulation of cell proliferation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0032369//negative regulation of lipid transport;GO:0070371//ERK1 and ERK2 cascade;GO:0034113//heterotypic cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0052066//entry of symbiont into host cell by promotion of host phagocytosis;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0045785//positive regulation of cell adhesion;GO:0030335//positive regulation of cell migration;GO:0007411//axon guidance;GO:0043277//apoptotic cell clearance;GO:0035987//endodermal cell differentiation;GO:2000425//regulation of apoptotic cell clearance;GO:0030198//extracellular matrix organization;GO:0010888//negative regulation of lipid storage",GO:0050840//extracellular matrix binding;GO:0001846//opsonin binding;GO:0005080//protein kinase C binding;GO:0050431//transforming growth factor beta binding;GO:0031994//insulin-like growth factor I binding;GO:0001618//virus receptor activity;GO:0002020//protease binding;GO:0001968//fibronectin binding;GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K06487//Focal adhesion;Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Regulation of actin cytoskeleton;ECM-receptor interaction;Dilated cardiomyopathy;Small cell lung cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Phagosome
3687,160,0,0,0,0,46,37,0,55,121,0,0,"ITGAX;integrin, alpha X (complement component 3 receptor 4 subunit)",GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0008305//integrin complex,GO:0034113//heterotypic cell-cell adhesion;GO:0030198//extracellular matrix organization;GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0007229//integrin-mediated signaling pathway;GO:0009887//organ morphogenesis;GO:0007155//cell adhesion,GO:0004872//receptor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K06462//Tuberculosis;Regulation of actin cytoskeleton
3688,0,18,0,5,63,1,22,0,26,332,0,1,"ITGB1;integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)",GO:0005604//basement membrane;GO:0032587//ruffle membrane;GO:0001669//acrosomal vesicle;GO:0042383//sarcolemma;GO:0055037//recycling endosome;GO:0043235//receptor complex;GO:0034678//integrin alpha8-beta1 complex;GO:0035748//myelin sheath abaxonal region;GO:0071438//invadopodium membrane;GO:0034666//integrin alpha2-beta1 complex;GO:0045121//membrane raft;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0030056//hemidesmosome;GO:0005925//focal adhesion;GO:0034679//integrin alpha9-beta1 complex;GO:0034677//integrin alpha7-beta1 complex;GO:0001726//ruffle;GO:0016020//membrane;GO:0009986//cell surface;GO:0032154//cleavage furrow;GO:0014704//intercalated disc;GO:0030175//filopodium;GO:0031594//neuromuscular junction;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0034667//integrin alpha3-beta1 complex;GO:0008305//integrin complex;GO:0005737//cytoplasm,GO:0071260//cellular response to mechanical stimulus;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0043065//positive regulation of apoptotic process;GO:0045214//sarcomere organization;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0034113//heterotypic cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0006968//cellular defense response;GO:0055007//cardiac muscle cell differentiation;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0008354//germ cell migration;GO:0010976//positive regulation of neuron projection development;GO:0070830//tight junction assembly;GO:0030183//B cell differentiation;GO:0034329//cell junction assembly;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0032594//protein transport within lipid bilayer;GO:0010811//positive regulation of cell-substrate adhesion;GO:0048675//axon extension;GO:0045665//negative regulation of neuron differentiation;GO:0034698//response to gonadotropin;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0030198//extracellular matrix organization;GO:0071305//cellular response to vitamin D;GO:0006874//cellular calcium ion homeostasis;GO:0001708//cell fate specification;GO:0042493//response to drug;GO:0001701//in utero embryonic development;GO:0045807//positive regulation of endocytosis;GO:0043149//stress fiber assembly;GO:0060135//maternal process involved in female pregnancy;GO:0007596//blood coagulation;GO:0021943//formation of radial glial scaffolds;GO:0007161//calcium-independent cell-matrix adhesion;GO:0045666//positive regulation of neuron differentiation;GO:0050776//regulation of immune response;GO:0031589//cell-substrate adhesion;GO:0016477//cell migration;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0014823//response to activity;GO:0008285//negative regulation of cell proliferation;GO:0009615//response to virus;GO:0051726//regulation of cell cycle;GO:2000811//negative regulation of anoikis;GO:0031345//negative regulation of cell projection organization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007159//leukocyte cell-cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0048333//mesodermal cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0050901//leukocyte tethering or rolling;GO:0071479//cellular response to ionizing radiation;GO:0033631//cell-cell adhesion mediated by integrin;GO:0008284//positive regulation of cell proliferation;GO:0001894//tissue homeostasis,GO:0003779//actin binding;GO:0043236//laminin binding;GO:0019904//protein domain specific binding;GO:0001948//glycoprotein binding;GO:0050839//cell adhesion molecule binding;GO:0019901//protein kinase binding;GO:0002020//protease binding;GO:0001618//virus receptor activity;GO:0042277//peptide binding;GO:0001968//fibronectin binding;GO:0051393//alpha-actinin binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005178//integrin binding,K05719//Bacterial invasion of epithelial cells;Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Toxoplasmosis;Leishmaniasis;Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Regulation of actin cytoskeleton;ECM-receptor interaction;Pathogenic Escherichia coli infection;Focal adhesion;Pathways in cancer;Axon guidance;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Pertussis;Small cell lung cancer
3689,62,0,0,0,0,13,0,0,2,1,2,0,"ITGB2;integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)",GO:0043235//receptor complex;GO:0031982//vesicle;GO:0008305//integrin complex;GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007160//cell-matrix adhesion;GO:0006915//apoptotic process;GO:0034113//heterotypic cell-cell adhesion;GO:0007596//blood coagulation;GO:0007155//cell adhesion;GO:0006954//inflammatory response;GO:0050776//regulation of immune response;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0002224//toll-like receptor signaling pathway;GO:0030593//neutrophil chemotaxis;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035987//endodermal cell differentiation;GO:0008360//regulation of cell shape;GO:0007267//cell-cell signaling;GO:0030198//extracellular matrix organization;GO:0045087//innate immune response;GO:0043113//receptor clustering;GO:0007159//leukocyte cell-cell adhesion;GO:0050730//regulation of peptidyl-tyrosine phosphorylation,GO:0030369//ICAM-3 receptor activity;GO:0001948//glycoprotein binding;GO:0050839//cell adhesion molecule binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K06464//Amoebiasis;Viral myocarditis;Leishmaniasis;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Regulation of actin cytoskeleton;Staphylococcus aureus infection;Tuberculosis;Pertussis;Legionellosis;Leukocyte transendothelial migration;Malaria;Phagosome;HTLV-I infection;Rheumatoid arthritis
369,0,0,0,14,16,0,5,0,17,0,8,0,"ARAF;A-Raf proto-oncogene, serine/threonine kinase",GO:0005739//mitochondrion,GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035556//intracellular signal transduction;GO:0032006//regulation of TOR signaling;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0006464//cellular protein modification process,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005057//receptor signaling protein activity,K08845//Long-term potentiation;Progesterone-mediated oocyte maturation;Alcoholism;Prostate cancer;Serotonergic synapse;Pancreatic cancer;Insulin signaling pathway;Pathways in cancer;Renal cell carcinoma;Colorectal cancer;ErbB signaling pathway;Bladder cancer;Chronic myeloid leukemia;Vascular smooth muscle contraction;Natural killer cell mediated cytotoxicity;Long-term depression;Acute myeloid leukemia;Glioma;Hepatitis C;Melanoma;Regulation of actin cytoskeleton;Non-small cell lung cancer;Endometrial cancer
3690,0,0,0,0,5,54,0,0,88,0,0,0,"ITGB3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005634//nucleus;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0032587//ruffle membrane;GO:0031258//lamellipodium membrane;GO:0005925//focal adhesion;GO:0031528//microvillus membrane;GO:0008305//integrin complex;GO:0031092//platelet alpha granule membrane;GO:0031527//filopodium membrane;GO:0042470//melanosome;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0060055//angiogenesis involved in wound healing;GO:0016049//cell growth;GO:0048333//mesodermal cell differentiation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0010595//positive regulation of endothelial cell migration;GO:0032147//activation of protein kinase activity;GO:0070527//platelet aggregation;GO:0035295//tube development;GO:0050748//negative regulation of lipoprotein metabolic process;GO:0016477//cell migration;GO:0031589//cell-substrate adhesion;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030168//platelet activation;GO:0045124//regulation of bone resorption;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0007044//cell-substrate junction assembly;GO:0007596//blood coagulation;GO:0050919//negative chemotaxis;GO:0046718//viral entry into host cell;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0002576//platelet degranulation;GO:0045715//negative regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0010888//negative regulation of lipid storage;GO:0030198//extracellular matrix organization;GO:0006457//protein folding;GO:0042060//wound healing;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007411//axon guidance;GO:0050900//leukocyte migration;GO:0007229//integrin-mediated signaling pathway;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0014909//smooth muscle cell migration;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0007160//cell-matrix adhesion;GO:0034113//heterotypic cell-cell adhesion;GO:0032369//negative regulation of lipid transport,GO:0005161//platelet-derived growth factor receptor binding;GO:0050840//extracellular matrix binding;GO:0004872//receptor activity;GO:0050839//cell adhesion molecule binding;GO:0042802//identical protein binding;GO:0002020//protease binding;GO:0003756//protein disulfide isomerase activity;GO:0001968//fibronectin binding;GO:0005515//protein binding;GO:0043184//vascular endothelial growth factor receptor 2 binding,K06493//Dilated cardiomyopathy;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Focal adhesion;Hematopoietic cell lineage;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Osteoclast differentiation
3691,0,1,29,0,0,11,10,54,49,121,1,1,"ITGB4;integrin, beta 4",GO:0008305//integrin complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0009986//cell surface;GO:0009925//basal plasma membrane;GO:0043235//receptor complex;GO:0005604//basement membrane;GO:0030056//hemidesmosome,GO:0046847//filopodium assembly;GO:0007229//integrin-mediated signaling pathway;GO:0009611//response to wounding;GO:0097186//amelogenesis;GO:0031581//hemidesmosome assembly;GO:0007155//cell adhesion;GO:0048870//cell motility;GO:0006914//autophagy;GO:0007160//cell-matrix adhesion;GO:0048565//digestive tract development;GO:0048333//mesodermal cell differentiation;GO:0072001//renal system development;GO:0030198//extracellular matrix organization;GO:0034329//cell junction assembly;GO:0035878//nail development;GO:0043588//skin development,GO:0005515//protein binding;GO:0001664//G-protein coupled receptor binding;GO:0004872//receptor activity,K06525//Dilated cardiomyopathy;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);ECM-receptor interaction;Regulation of actin cytoskeleton
3692,0,2,0,6,2,0,21,4,13,0,0,102,EIF6;eukaryotic translation initiation factor 6,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005638//lamin filament;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0000054//ribosomal subunit export from nucleus;GO:0006413//translational initiation;GO:0042256//mature ribosome assembly;GO:0042273//ribosomal large subunit biogenesis,GO:0003743//translation initiation factor activity;GO:0043022//ribosome binding;GO:0005515//protein binding;GO:0043023//ribosomal large subunit binding,K03264//Ribosome biogenesis in eukaryotes
3693,1,0,0,0,3,0,8,2,76,0,0,278,"ITGB5;integrin, beta 5",GO:0043235//receptor complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031252//cell leading edge;GO:0045335//phagocytic vesicle;GO:0005925//focal adhesion;GO:0009986//cell surface,"GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0030198//extracellular matrix organization;GO:0090136//epithelial cell-cell adhesion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0043149//stress fiber assembly;GO:0007160//cell-matrix adhesion;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006936//muscle contraction;GO:0035987//endodermal cell differentiation",GO:0004872//receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding,K06588//Regulation of actin cytoskeleton;Phagosome;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Focal adhesion;Dilated cardiomyopathy
3694,39,17,0,0,0,38,37,0,22,0,0,0,"ITGB6;integrin, beta 6",GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0008305//integrin complex,GO:0007275//multicellular organismal development;GO:0009615//response to virus;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0006954//inflammatory response;GO:0016032//viral process,GO:0005178//integrin binding;GO:0001618//virus receptor activity,K06589//Focal adhesion;Dilated cardiomyopathy;Regulation of actin cytoskeleton;ECM-receptor interaction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
3695,0,0,0,0,0,0,23,0,7,281,0,0,"ITGB7;integrin, beta 7",GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0043235//receptor complex;GO:0008305//integrin complex,GO:0007229//integrin-mediated signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030198//extracellular matrix organization;GO:0050901//leukocyte tethering or rolling;GO:0050776//regulation of immune response;GO:0043113//receptor clustering;GO:0007275//multicellular organismal development;GO:0009615//response to virus;GO:0007155//cell adhesion;GO:0034113//heterotypic cell-cell adhesion;GO:0007160//cell-matrix adhesion;GO:0072678//T cell migration,GO:0050839//cell adhesion molecule binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0001618//virus receptor activity,K06590//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Intestinal immune network for IgA production;Transcriptional misregulation in cancer;Dilated cardiomyopathy;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);Focal adhesion
3696,70,0,0,0,1,55,54,0,65,0,8,0,"ITGB8;integrin, beta 8",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0008305//integrin complex,GO:0007160//cell-matrix adhesion;GO:0060674//placenta blood vessel development;GO:0007155//cell adhesion;GO:0010628//positive regulation of gene expression;GO:0001573//ganglioside metabolic process;GO:0030198//extracellular matrix organization;GO:0010629//negative regulation of gene expression;GO:0051216//cartilage development;GO:0007229//integrin-mediated signaling pathway,GO:0004872//receptor activity;GO:0005102//receptor binding,K06591//Focal adhesion;Dilated cardiomyopathy;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Cell adhesion molecules (CAMs)
3697,0,0,0,0,0,16,28,23,65,0,0,0,ITIH1;inter-alpha-trypsin inhibitor heavy chain 1,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,GO:0030212//hyaluronan metabolic process;GO:0010951//negative regulation of endopeptidase activity,GO:0005509//calcium ion binding;GO:0004867//serine-type endopeptidase inhibitor activity,K05316//MAPK signaling pathway;K04861//MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy
3698,181,0,28,0,0,0,0,0,67,0,0,0,ITIH2;inter-alpha-trypsin inhibitor heavy chain 2,GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process,GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K04860//MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction;K04861//Cardiac muscle contraction;Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Hypertrophic cardiomyopathy (HCM)
3699,0,0,0,0,0,0,15,1,40,0,5,0,ITIH3;inter-alpha-trypsin inhibitor heavy chain 3,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity,K05316//MAPK signaling pathway
37,0,19,2,38,61,0,0,5,6,1,5,361,"ACADVL;acyl-CoA dehydrogenase, very long chain",GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0090181//regulation of cholesterol metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006635//fatty acid beta-oxidation;GO:0015980//energy derivation by oxidation of organic compounds;GO:0030855//epithelial cell differentiation;GO:0001659//temperature homeostasis;GO:0044267//cellular protein metabolic process;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046322//negative regulation of fatty acid oxidation;GO:0044255//cellular lipid metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044281//small molecule metabolic process,GO:0003995//acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0004466//long-chain-acyl-CoA dehydrogenase activity,K09479//Metabolic pathways;Fatty acid metabolism
3700,0,0,0,0,0,0,11,70,34,0,0,0,"ITIH4;inter-alpha-trypsin inhibitor heavy chain family, member 4",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region,GO:0006953//acute-phase response;GO:0034097//response to cytokine;GO:0010951//negative regulation of endopeptidase activity;GO:0030212//hyaluronan metabolic process,GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K10798//NF-kappa B signaling pathway;Base excision repair;K05316//MAPK signaling pathway;K04860//Dilated cardiomyopathy;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
3702,0,0,0,0,0,0,3,0,56,0,1,0,ITK;IL2-inducible T-cell kinase,GO:0005829//cytosol;GO:0005911//cell-cell junction,GO:0001865//NK T cell differentiation;GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0001816//cytokine production;GO:0032609//interferon-gamma production;GO:0050852//T cell receptor signaling pathway;GO:0042110//T cell activation;GO:0032633//interleukin-4 production;GO:0006968//cellular defense response;GO:0002250//adaptive immune response,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,K07363//Chemokine signaling pathway;T cell receptor signaling pathway;Leukocyte transendothelial migration
3703,0,0,0,7,10,0,28,0,51,0,0,0,"STT3A;STT3A, subunit of the oligosaccharyltransferase complex (catalytic)",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex;GO:0005789//endoplasmic reticulum membrane,GO:0043687//post-translational protein modification;GO:0043686//co-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding,K07151//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
3704,0,0,0,0,7,0,14,0,9,0,0,0,ITPA;inosine triphosphatase (nucleoside triphosphate pyrophosphatase),GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0009204//deoxyribonucleoside triphosphate catabolic process;GO:0051276//chromosome organization;GO:0006193//ITP catabolic process,GO:0036220//ITP diphosphatase activity;GO:0035870//dITP diphosphatase activity;GO:0036222//XTP diphosphatase activity;GO:0046872//metal ion binding;GO:0000166//nucleotide binding,K01519//Metabolic pathways;Drug metabolism - other enzymes;Purine metabolism;Pyrimidine metabolism
3705,0,0,0,6,26,9,16,0,28,0,7,0,ITPK1;inositol-tetrakisphosphate 1-kinase,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0043647//inositol phosphate metabolic process;GO:0016311//dephosphorylation;GO:0032957//inositol trisphosphate metabolic process;GO:0007596//blood coagulation;GO:0016310//phosphorylation,"GO:0052726//inositol-1,3,4-trisphosphate 5-kinase activity;GO:0016853//isomerase activity;GO:0005524//ATP binding;GO:0052831//inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity;GO:0052725//inositol-1,3,4-trisphosphate 6-kinase activity;GO:0000287//magnesium ion binding;GO:0052825//inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity;GO:0047325//inositol tetrakisphosphate 1-kinase activity;GO:0003824//catalytic activity;GO:0052835//inositol-3,4,6-trisphosphate 1-kinase activity;GO:0052830//inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity",K00913//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
3706,0,0,0,0,0,0,26,0,17,0,0,0,ITPKA;inositol-trisphosphate 3-kinase A,GO:0005829//cytosol;GO:0043197//dendritic spine,GO:0030036//actin cytoskeleton organization;GO:0048167//regulation of synaptic plasticity;GO:0006020//inositol metabolic process;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0043647//inositol phosphate metabolic process;GO:0006468//protein phosphorylation;GO:0097062//dendritic spine maintenance;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process,"GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0048365//Rac GTPase binding",K00911//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Calcium signaling pathway
3707,0,22,0,21,85,0,29,0,39,334,4,0,ITPKB;inositol-trisphosphate 3-kinase B,GO:0005829//cytosol,GO:0000165//MAPK cascade;GO:0007166//cell surface receptor signaling pathway;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0043647//inositol phosphate metabolic process;GO:0046579//positive regulation of Ras protein signal transduction;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0045059//positive thymic T cell selection,"GO:0005515//protein binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding",K00911//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Calcium signaling pathway
3708,0,0,0,26,57,107,27,1,135,0,18,1,"ITPR1;inositol 1,4,5-trisphosphate receptor, type 1",GO:0005789//endoplasmic reticulum membrane;GO:0031094//platelet dense tubular network;GO:0005730//nucleolus;GO:0016529//sarcoplasmic reticulum;GO:0005637//nuclear inner membrane;GO:0014069//postsynaptic density;GO:0031095//platelet dense tubular network membrane;GO:0031088//platelet dense granule membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005955//calcineurin complex,GO:0001666//response to hypoxia;GO:0006112//energy reserve metabolic process;GO:0007596//blood coagulation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0050849//negative regulation of calcium-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0009791//post-embryonic development;GO:0048016//inositol phosphate-mediated signaling;GO:0050796//regulation of insulin secretion;GO:0051209//release of sequestered calcium ion into cytosol;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0050882//voluntary musculoskeletal movement;GO:0006816//calcium ion transport;GO:0007202//activation of phospholipase C activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,"GO:0019855//calcium channel inhibitor activity;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding",K04958//Long-term potentiation;Serotonergic synapse;Pancreatic secretion;Huntington's disease;Phosphatidylinositol signaling system;GnRH signaling pathway;Gap junction;Dopaminergic synapse;Vascular smooth muscle contraction;Oocyte meiosis;Glutamatergic synapse;Salivary secretion;Retrograde endocannabinoid signaling;Calcium signaling pathway;Cholinergic synapse;Long-term depression;Gastric acid secretion;Alzheimer's disease
3709,101,15,0,59,123,25,29,0,115,116,0,0,"ITPR2;inositol 1,4,5-trisphosphate receptor, type 2",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031095//platelet dense tubular network membrane;GO:0005938//cell cortex;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex;GO:0033017//sarcoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0007202//activation of phospholipase C activity;GO:0071361//cellular response to ethanol;GO:0050796//regulation of insulin secretion;GO:0007165//signal transduction;GO:0048016//inositol phosphate-mediated signaling;GO:0030168//platelet activation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0001666//response to hypoxia;GO:0006810//transport;GO:0071320//cellular response to cAMP;GO:0007596//blood coagulation,"GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0035091//phosphatidylinositol binding",K04959//Vascular smooth muscle contraction;Oocyte meiosis;Glutamatergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Dopaminergic synapse;Gap junction;Long-term potentiation;Serotonergic synapse;Pancreatic secretion;Alzheimer's disease;Gastric acid secretion;Cholinergic synapse;Long-term depression;Salivary secretion;Calcium signaling pathway;Retrograde endocannabinoid signaling
3710,22,164,51,114,115,15,57,134,157,45,169,0,"ITPR3;inositol 1,4,5-trisphosphate receptor, type 3",GO:0005640//nuclear outer membrane;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex;GO:0005730//nucleolus;GO:0031095//platelet dense tubular network membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005654//nucleoplasm;GO:0045177//apical part of cell;GO:0043209//myelin sheath;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0006112//energy reserve metabolic process;GO:0060291//long-term synaptic potentiation;GO:0007596//blood coagulation;GO:0060402//calcium ion transport into cytosol;GO:0051592//response to calcium ion;GO:0070588//calcium ion transmembrane transport;GO:0051291//protein heterooligomerization;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050913//sensory perception of bitter taste;GO:0007613//memory;GO:0007165//signal transduction;GO:0048016//inositol phosphate-mediated signaling;GO:0030168//platelet activation;GO:0050796//regulation of insulin secretion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0050917//sensory perception of umami taste;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0051260//protein homooligomerization;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0050916//sensory perception of sweet taste;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,"GO:0000822//inositol hexakisphosphate binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0005220//inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding",K04960//Serotonergic synapse;Pancreatic secretion;Long-term potentiation;GnRH signaling pathway;Phosphatidylinositol signaling system;Dopaminergic synapse;Gap junction;Taste transduction;Glutamatergic synapse;Vascular smooth muscle contraction;Oocyte meiosis;Retrograde endocannabinoid signaling;Calcium signaling pathway;Salivary secretion;Cholinergic synapse;Long-term depression;Gastric acid secretion;Alzheimer's disease
3712,86,19,2,25,86,0,55,0,63,0,7,0,IVD;isovaleryl-CoA dehydrogenase,GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006552//leucine catabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0055114//oxidation-reduction process,GO:0050660//flavin adenine dinucleotide binding;GO:0008470//isovaleryl-CoA dehydrogenase activity,"K00253//Valine, leucine and isoleucine degradation;Metabolic pathways;Butanoate metabolism;Fatty acid metabolism;Geraniol degradation;Biosynthesis of secondary metabolites"
3713,0,0,0,0,0,0,0,67,0,0,0,0,IVL;involucrin,GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0031424//keratinization;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0010224//response to UV-B;GO:0030216//keratinocyte differentiation;GO:0018149//peptide cross-linking,"GO:0005198//structural molecule activity;GO:0030674//protein binding, bridging",K09187//Lysine degradation
3714,0,0,0,0,0,42,47,0,65,0,0,0,JAG2;jagged 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0001701//in utero embryonic development;GO:0030217//T cell differentiation;GO:0003016//respiratory system process;GO:0007049//cell cycle;GO:0016331//morphogenesis of embryonic epithelium;GO:0007220//Notch receptor processing;GO:0042475//odontogenesis of dentin-containing tooth;GO:1990134//epithelial cell apoptotic process involved in palatal shelf morphogenesis;GO:0042127//regulation of cell proliferation;GO:0030154//cell differentiation;GO:0030334//regulation of cell migration;GO:0045061//thymic T cell selection;GO:0042492//gamma-delta T cell differentiation;GO:0007219//Notch signaling pathway;GO:0001501//skeletal system development;GO:0030155//regulation of cell adhesion;GO:0009912//auditory receptor cell fate commitment;GO:0007283//spermatogenesis,GO:0005112//Notch binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0008083//growth factor activity,K06052//Notch signaling pathway
3716,212,39,3,52,199,29,17,0,134,6,12,0,JAK1;Janus kinase 1,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0012505//endomembrane system,GO:0007167//enzyme linked receptor protein signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0035556//intracellular signal transduction;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038110//interleukin-2-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0046677//response to antibiotic;GO:0046777//protein autophosphorylation,GO:0005131//growth hormone receptor binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0031730//CCR5 chemokine receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity,K11217//Herpes simplex infection;Leishmaniasis;Osteoclast differentiation;Toxoplasmosis;Hepatitis C;Measles;Epstein-Barr virus infection;Pathways in cancer;Pancreatic cancer;HTLV-I infection;Jak-STAT signaling pathway;Tuberculosis;Influenza A
3717,0,0,1,3,69,33,0,0,40,285,9,0,JAK2;Janus kinase 2,GO:0005829//cytosol;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0005901//caveola;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0031904//endosome lumen;GO:0005856//cytoskeleton,"GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0032024//positive regulation of insulin secretion;GO:0043524//negative regulation of neuron apoptotic process;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0022408//negative regulation of cell-cell adhesion;GO:0007259//JAK-STAT cascade;GO:0009755//hormone-mediated signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0035722//interleukin-12-mediated signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0060396//growth hormone receptor signaling pathway;GO:0046677//response to antibiotic;GO:0045597//positive regulation of cell differentiation;GO:0050867//positive regulation of cell activation;GO:0034612//response to tumor necrosis factor;GO:0033194//response to hydroperoxide;GO:0030154//cell differentiation;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0007262//STAT protein import into nucleus;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0050727//regulation of inflammatory response;GO:0061180//mammary gland epithelium development;GO:0032496//response to lipopolysaccharide;GO:0031103//axon regeneration;GO:0032731//positive regulation of interleukin-1 beta production;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050729//positive regulation of inflammatory response;GO:0007596//blood coagulation;GO:0034050//host programmed cell death induced by symbiont;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0045822//negative regulation of heart contraction;GO:0043388//positive regulation of DNA binding;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0035409//histone H3-Y41 phosphorylation;GO:0000186//activation of MAPKK activity;GO:0030041//actin filament polymerization;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0031959//mineralocorticoid receptor signaling pathway;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0006915//apoptotic process;GO:0042508//tyrosine phosphorylation of Stat1 protein;GO:0006468//protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0006928//cellular component movement;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043392//negative regulation of DNA binding;GO:0060399//positive regulation of growth hormone receptor signaling pathway;GO:0042977//activation of JAK2 kinase activity;GO:0007165//signal transduction;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0070671//response to interleukin-12;GO:0046777//protein autophosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0030335//positive regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007498//mesoderm development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0030218//erythrocyte differentiation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production",GO:0042393//histone binding;GO:0005515//protein binding;GO:0035401//histone kinase activity (H3-Y41 specific);GO:0008022//protein C-terminus binding;GO:0004713//protein tyrosine kinase activity;GO:0033130//acetylcholine receptor binding;GO:0005131//growth hormone receptor binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0051428//peptide hormone receptor binding;GO:0020037//heme binding;GO:0005143//interleukin-12 receptor binding;GO:0005524//ATP binding;GO:0042169//SH2 domain binding;GO:0043560//insulin receptor substrate binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005102//receptor binding;GO:0031702//type 1 angiotensin receptor binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity,K04447//Toxoplasmosis;Leishmaniasis;Adipocytokine signaling pathway;Herpes simplex infection;Measles;Jak-STAT signaling pathway;Cholinergic synapse;Chemokine signaling pathway;Influenza A;Tuberculosis
3718,20,0,0,0,0,16,24,156,14,0,8,177,JAK3;Janus kinase 3,GO:0005829//cytosol;GO:0016020//membrane;GO:0012505//endomembrane system;GO:0005856//cytoskeleton,GO:0070669//response to interleukin-2;GO:0071104//response to interleukin-9;GO:0070232//regulation of T cell apoptotic process;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0032695//negative regulation of interleukin-12 production;GO:0035556//intracellular signal transduction;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0045087//innate immune response;GO:0070672//response to interleukin-15;GO:0007260//tyrosine phosphorylation of STAT protein;GO:0002731//negative regulation of dendritic cell cytokine production;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043029//T cell homeostasis;GO:0032693//negative regulation of interleukin-10 production;GO:0070670//response to interleukin-4;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0050868//negative regulation of T cell activation;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:0006468//protein phosphorylation;GO:0045221//negative regulation of FasL biosynthetic process;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0030183//B cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035771//interleukin-4-mediated signaling pathway;GO:0007262//STAT protein import into nucleus,GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding,K11218//HTLV-I infection;Jak-STAT signaling pathway;Primary immunodeficiency;Chemokine signaling pathway;Epstein-Barr virus infection;Measles
372,13,220,0,93,336,0,40,0,15,0,1,0,ARCN1;archain 1,GO:0030126//COPI vesicle coat;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0030131//clathrin adaptor complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,"GO:0008344//adult locomotory behavior;GO:0048205//COPI coating of Golgi vesicle;GO:0021691//cerebellar Purkinje cell layer maturation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport;GO:0061024//membrane organization;GO:0043473//pigmentation",GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
3720,0,11,0,0,21,29,68,0,34,0,9,0,"JARID2;jumonji, AT rich interactive domain 2",GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0035097//histone methyltransferase complex,"GO:0051574//positive regulation of histone H3-K9 methylation;GO:0048538//thymus development;GO:0048536//spleen development;GO:0016568//chromatin modification;GO:0001889//liver development;GO:0048863//stem cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0031061//negative regulation of histone methylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development",GO:0003677//DNA binding;GO:0032452//histone demethylase activity;GO:0003682//chromatin binding,-
3725,0,11,3,1,0,0,0,41,42,0,0,0,JUN;jun proto-oncogene,GO:0000228//nuclear chromosome;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005719//nuclear euchromatin;GO:0005829//cytosol;GO:0017053//transcriptional repressor complex,"GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0001938//positive regulation of endothelial cell proliferation;GO:0051365//cellular response to potassium ion starvation;GO:0007612//learning;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0031103//axon regeneration;GO:0042493//response to drug;GO:0043922//negative regulation by host of viral transcription;GO:0071277//cellular response to calcium ion;GO:0060395//SMAD protein signal transduction;GO:0035026//leading edge cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus;GO:0034134//toll-like receptor 2 signaling pathway;GO:0009314//response to radiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034097//response to cytokine;GO:0045740//positive regulation of DNA replication;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:0045657//positive regulation of monocyte differentiation;GO:0051591//response to cAMP;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043525//positive regulation of neuron apoptotic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0051726//regulation of cell cycle;GO:0042542//response to hydrogen peroxide;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0045087//innate immune response;GO:0001525//angiogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0001889//liver development;GO:0034138//toll-like receptor 3 signaling pathway;GO:0030224//monocyte differentiation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0043923//positive regulation by host of viral transcription;GO:0031953//negative regulation of protein autophosphorylation;GO:0007623//circadian rhythm;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0032321//positive regulation of Rho GTPase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0007568//aging;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0003151//outflow tract morphogenesis;GO:0051899//membrane depolarization;GO:0001774//microglial cell activation",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0070412//R-SMAD binding;GO:0003677//DNA binding;GO:0071837//HMG box domain binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0008134//transcription factor binding;GO:0035497//cAMP response element binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003713//transcription coactivator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0005100//Rho GTPase activator activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K04448//MAPK signaling pathway;Herpes simplex infection;Amphetamine addiction;T cell receptor signaling pathway;Wnt signaling pathway;ErbB signaling pathway;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection;Colorectal cancer;Epstein-Barr virus infection;Cocaine addiction;GnRH signaling pathway;Pathways in cancer;Rheumatoid arthritis;Salmonella infection;Pertussis;Toll-like receptor signaling pathway;Influenza A;Leishmaniasis;Osteoclast differentiation;Neurotrophin signaling pathway;Focal adhesion;Chagas disease (American trypanosomiasis);HTLV-I infection;B cell receptor signaling pathway
3726,0,0,0,0,0,0,0,0,19,0,4,0,JUNB;jun B proto-oncogene,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000785//chromatin;GO:0005654//nucleoplasm,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009416//response to light stimulus;GO:0001649//osteoblast differentiation;GO:0051591//response to cAMP;GO:0032870//cellular response to hormone stimulus;GO:0032570//response to progesterone;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001829//trophectodermal cell differentiation;GO:0060136//embryonic process involved in female pregnancy;GO:0045597//positive regulation of cell differentiation;GO:0051412//response to corticosterone;GO:0009612//response to mechanical stimulus;GO:0034097//response to cytokine;GO:0030316//osteoclast differentiation;GO:0046697//decidualization;GO:0043434//response to peptide hormone;GO:0071277//cellular response to calcium ion;GO:0042493//response to drug;GO:0033687//osteoblast proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001570//vasculogenesis;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0060716//labyrinthine layer blood vessel development;GO:0010467//gene expression;GO:0051726//regulation of cell cycle",GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003690//double-stranded DNA binding,K09028//Osteoclast differentiation
3727,0,34,0,4,31,0,0,1,22,0,0,0,JUND;jun D proto-oncogene,GO:0043234//protein complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006366//transcription from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide;GO:0009612//response to mechanical stimulus;GO:0043434//response to peptide hormone;GO:0002076//osteoblast development;GO:0007623//circadian rhythm;GO:0007568//aging;GO:0014070//response to organic cyclic compound;GO:0071277//cellular response to calcium ion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009416//response to light stimulus;GO:0045669//positive regulation of osteoblast differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K04449//MAPK signaling pathway;Osteoclast differentiation
3728,0,2,1,10,2,8,16,79,26,0,17,0,JUP;junction plakoglobin,GO:0005925//focal adhesion;GO:0030056//hemidesmosome;GO:0016323//basolateral plasma membrane;GO:0005916//fascia adherens;GO:0005634//nucleus;GO:0005915//zonula adherens;GO:0005667//transcription factor complex;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0014704//intercalated disc;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0016328//lateral plasma membrane;GO:0030018//Z disc;GO:0030057//desmosome;GO:0071665//gamma-catenin-TCF7L2 complex;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0016342//catenin complex;GO:0005886//plasma membrane;GO:0032993//protein-DNA complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0005913//cell-cell adherens junction,GO:0050982//detection of mechanical stimulus;GO:0003136//negative regulation of heart induction by canonical Wnt signaling pathway;GO:0042307//positive regulation of protein import into nucleus;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0003181//atrioventricular valve morphogenesis;GO:0007369//gastrulation;GO:0016477//cell migration;GO:0042127//regulation of cell proliferation;GO:0007399//nervous system development;GO:0071603//endothelial cell-cell adhesion;GO:0090002//establishment of protein localization to plasma membrane;GO:0051291//protein heterooligomerization;GO:0000902//cell morphogenesis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045216//cell-cell junction organization;GO:0048599//oocyte development;GO:0002159//desmosome assembly;GO:0086005//ventricular cardiac muscle cell action potential;GO:0034332//adherens junction organization;GO:0007398//ectoderm development;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0034329//cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0071681//cellular response to indole-3-methanol;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0043588//skin development;GO:0016331//morphogenesis of embryonic epithelium;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0045294//alpha-catenin binding;GO:0005199//structural constituent of cell wall;GO:0045296//cadherin binding;GO:0005198//structural molecule activity;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0003713//transcription coactivator activity,K10056//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Acute myeloid leukemia;Transcriptional misregulation in cancer
373,0,0,0,15,4,8,0,0,30,0,0,0,TRIM23;tripartite motif containing 23,GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane;GO:0005634//nucleus,GO:0016567//protein ubiquitination;GO:0006184//GTP catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0007264//small GTPase mediated signal transduction;GO:0016032//viral process,GO:0008047//enzyme activator activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0003924//GTPase activity;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
3730,44,0,0,0,0,0,26,0,65,0,0,0,KAL1;Kallmann syndrome 1 sequence,GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0006935//chemotaxis;GO:0010951//negative regulation of endopeptidase activity;GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0007411//axon guidance,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding;GO:0008201//heparin binding,-
373156,83,1,0,7,0,0,0,0,0,0,0,0,GSTK1;glutathione S-transferase kappa 1,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005743//mitochondrial inner membrane;GO:0016020//membrane;GO:0005759//mitochondrial matrix;GO:0005777//peroxisome,GO:0055114//oxidation-reduction process;GO:0006749//glutathione metabolic process;GO:0030855//epithelial cell differentiation,GO:0005102//receptor binding;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0015035//protein disulfide oxidoreductase activity,K13299//Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Glutathione metabolism;Peroxisome
3732,0,0,0,0,0,0,0,0,9,0,0,0,CD82;CD82 molecule,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,GO:0005515//protein binding,K06509//p53 signaling pathway
3735,71,11,2,34,40,9,0,0,1,0,0,0,KARS;lysyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0006430//lysyl-tRNA aminoacylation;GO:0016032//viral process;GO:0008219//cell death;GO:0006418//tRNA aminoacylation for protein translation;GO:0008033//tRNA processing;GO:0010467//gene expression;GO:0015966//diadenosine tetraphosphate biosynthetic process,GO:0004824//lysine-tRNA ligase activity;GO:0016597//amino acid binding;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K04567//Aminoacyl-tRNA biosynthesis;Mismatch repair
373509,0,0,1,58,41,0,0,0,16,0,11,0,USP50;ubiquitin specific peptidase 50,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity,K11839//Endocytosis
3737,0,0,0,0,0,0,2,0,10,0,0,0,"KCNA2;potassium voltage-gated channel, shaker-related subfamily, member 2",GO:0044224//juxtaparanode region of axon;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization;GO:0021633//optic nerve structural organization,GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0015271//outward rectifier potassium channel activity,-
3738,0,0,0,0,0,0,73,0,27,0,0,0,"KCNA3;potassium voltage-gated channel, shaker-related subfamily, member 3",GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization,GO:0005251//delayed rectifier potassium channel activity;GO:0005244//voltage-gated ion channel activity;GO:0015271//outward rectifier potassium channel activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer
373863,66,197,80,319,621,0,1,180,59,3,529,1,DND1;DND microRNA-mediated repression inhibitor 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0060965//negative regulation of gene silencing by miRNA;GO:0007281//germ cell development,GO:0017091//AU-rich element binding;GO:0000166//nucleotide binding;GO:0035198//miRNA binding,-
3739,0,0,0,0,0,0,0,39,0,0,19,0,"KCNA4;potassium voltage-gated channel, shaker-related subfamily, member 4",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport,GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0030955//potassium ion binding;GO:0005515//protein binding,-
3741,0,0,0,0,0,9,0,0,29,0,0,0,"KCNA5;potassium voltage-gated channel, shaker-related subfamily, member 5",GO:0008076//voltage-gated potassium channel complex;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0046691//intracellular canaliculus;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0014704//intercalated disc;GO:0030018//Z disc,GO:0086014//atrial cardiac muscle cell action potential;GO:0042391//regulation of membrane potential;GO:0055075//potassium ion homeostasis;GO:2000288//positive regulation of myoblast proliferation;GO:0071435//potassium ion export;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0050796//regulation of insulin secretion;GO:0043267//negative regulation of potassium ion transport;GO:0006813//potassium ion transport;GO:0060081//membrane hyperpolarization;GO:0043266//regulation of potassium ion transport;GO:0051260//protein homooligomerization;GO:0019229//regulation of vasoconstriction;GO:0007268//synaptic transmission;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0001666//response to hypoxia;GO:0086091//regulation of heart rate by cardiac conduction;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle,GO:0019870//potassium channel inhibitor activity;GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0019901//protein kinase binding;GO:0015271//outward rectifier potassium channel activity;GO:0005102//receptor binding;GO:0097110//scaffold protein binding;GO:0005251//delayed rectifier potassium channel activity;GO:0051393//alpha-actinin binding;GO:0005515//protein binding,-
3742,55,0,0,0,0,8,29,19,47,0,24,0,"KCNA6;potassium voltage-gated channel, shaker-related subfamily, member 6",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization,GO:0005251//delayed rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity,-
374286,161,0,0,0,0,0,0,22,14,0,0,0,CDRT1;CMT1A duplicated region transcript 1,-,-,-,-
374291,0,1,23,0,13,0,0,0,0,60,0,0,"NDUFS7;NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)",GO:0043025//neuronal cell body;GO:0097060//synaptic membrane;GO:0043005//neuron projection;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0003954//NADH dehydrogenase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0048038//quinone binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0002020//protease binding",K03940//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
3743,0,0,0,0,0,0,25,0,39,0,0,0,"KCNA7;potassium voltage-gated channel, shaker-related subfamily, member 7",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0051260//protein homooligomerization;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity,-
374308,0,0,0,0,0,0,0,0,41,29,0,0,PTCHD3;patched domain containing 3,GO:0016021//integral component of membrane;GO:0097225//sperm midpiece,GO:0007286//spermatid development;GO:0007165//signal transduction,GO:0008158//hedgehog receptor activity,K12385//Lysosome
374354,0,69,0,46,190,19,68,0,44,246,0,0,NHLRC2;NHL repeat containing 2,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation
374378,7,0,0,0,0,33,19,0,14,154,0,344,GALNT18;polypeptide N-acetylgalactosaminyltransferase 18,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
374383,0,0,0,0,0,2,0,45,38,0,3,0,NCR3LG1;natural killer cell cytotoxicity receptor 3 ligand 1,GO:0019028//viral capsid;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,GO:0005198//structural molecule activity,K01330//Pertussis;Complement and coagulation cascades;Systemic lupus erythematosus;Phagosome;Staphylococcus aureus infection;K06551//Osteoclast differentiation;K14005//Protein processing in endoplasmic reticulum
374393,0,0,0,0,0,0,0,0,4,23,0,0,"FAM111B;family with sequence similarity 111, member B",-,GO:0008152//metabolic process,GO:0003824//catalytic activity,-
374395,0,0,0,0,31,0,0,0,0,0,21,0,TMEM179B;transmembrane protein 179B,GO:0016021//integral component of membrane,-,-,-
3744,0,0,0,0,0,0,14,0,0,0,0,0,"KCNA10;potassium voltage-gated channel, shaker-related subfamily, member 10",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005221//intracellular cyclic nucleotide activated cation channel activity;GO:0005251//delayed rectifier potassium channel activity,-
374403,0,0,0,0,0,15,25,0,10,0,0,0,"TBC1D10C;TBC1 domain family, member 10C",GO:0016020//membrane;GO:0031527//filopodium membrane;GO:0005886//plasma membrane,"GO:0032851//positive regulation of Rab GTPase activity;GO:0042147//retrograde transport, endosome to Golgi;GO:1902017//regulation of cilium assembly",GO:0005097//Rab GTPase activator activity,-
374407,0,0,0,0,0,0,0,0,5,0,7,0,"DNAJB13;DnaJ (Hsp40) homolog, subfamily B, member 13",-,GO:0006457//protein folding,GO:0051082//unfolded protein binding,-
374454,0,0,21,0,0,25,3,0,42,111,0,0,KRT77;keratin 77,GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
374462,2,0,0,0,0,25,12,0,133,382,10,0,"PTPRQ;protein tyrosine phosphatase, receptor type, Q",GO:0016021//integral component of membrane,GO:0045598//regulation of fat cell differentiation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity,K06252//Focal adhesion;ECM-receptor interaction
374470,0,0,0,0,0,0,0,0,1,0,0,0,C12orf42;chromosome 12 open reading frame 42,-,-,-,-
3745,19,0,0,0,0,19,27,0,46,0,0,0,"KCNB1;potassium voltage-gated channel, Shab-related subfamily, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0032590//dendrite membrane;GO:0045211//postsynaptic membrane;GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0051260//protein homooligomerization;GO:0071805//potassium ion transmembrane transport;GO:0044281//small molecule metabolic process;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0047485//protein N-terminus binding;GO:0005251//delayed rectifier potassium channel activity;GO:0005515//protein binding;GO:0015271//outward rectifier potassium channel activity,K04885//Taste transduction
374569,0,0,0,0,0,6,11,0,1,0,0,119,ASPG;asparaginase,-,GO:0006644//phospholipid metabolic process;GO:0016042//lipid catabolic process;GO:0006528//asparagine metabolic process,GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0004067//asparaginase activity;GO:0004622//lysophospholipase activity,-
3746,41,0,0,0,0,0,54,25,55,0,6,520,"KCNC1;potassium voltage-gated channel, Shaw-related subfamily, member 1",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport,GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,-
374618,87,0,0,0,53,0,21,0,18,0,4,0,TEX9;testis expressed 9,-,-,-,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
374650,0,0,0,1,0,0,0,0,17,0,6,1,"GOLGA6L5P;golgin A6 family-like 5, pseudogene",-,-,-,-
374654,85,0,0,0,0,39,20,71,39,148,4,0,KIF7;kinesin family member 7,GO:0005929//cilium;GO:0005871//kinesin complex,GO:0007018//microtubule-based movement;GO:0007224//smoothened signaling pathway;GO:0045880//positive regulation of smoothened signaling pathway;GO:0045879//negative regulation of smoothened signaling pathway;GO:0006200//ATP catabolic process;GO:0021591//ventricular system development;GO:0008152//metabolic process,GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,-
374655,0,468,296,592,690,30,46,602,181,0,1104,1,ZNF710;zinc finger protein 710,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
374659,0,0,0,6,0,0,0,0,0,0,0,0,HDDC3;HD domain containing 3,-,GO:0008152//metabolic process,"GO:0008893//guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity;GO:0046872//metal ion binding",K01139//Purine metabolism
374666,0,0,1,0,0,18,0,1,24,0,0,7,WASH3P;WAS protein family homolog 3 pseudogene,GO:0030027//lamellipodium;GO:0055037//recycling endosome;GO:0071203//WASH complex;GO:0030175//filopodium;GO:0005769//early endosome;GO:0055038//recycling endosome membrane;GO:0031901//early endosome membrane,"GO:0042147//retrograde transport, endosome to Golgi;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0016197//endosomal transport",GO:0003779//actin binding;GO:0043014//alpha-tubulin binding,K12495//Endocytosis
3747,0,0,0,9,7,56,0,0,40,0,14,0,"KCNC2;potassium voltage-gated channel, Shaw-related subfamily, member 2",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0001508//action potential;GO:0051260//protein homooligomerization;GO:0044281//small molecule metabolic process,GO:0005251//delayed rectifier potassium channel activity,-
374739,0,0,0,0,0,15,0,0,0,113,0,0,"TEPP;testis, prostate and placenta expressed",GO:0005576//extracellular region,-,-,-
374768,0,0,0,0,0,0,4,0,11,0,0,0,SPEM1;spermatid maturation 1,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0030317//sperm motility,-,-
374786,0,0,21,9,78,13,0,0,152,0,25,0,EFCAB5;EF-hand calcium binding domain 5,-,-,GO:0005509//calcium ion binding,K04574//Amyotrophic lateral sclerosis (ALS);K14000//Protein processing in endoplasmic reticulum;K04573//Amyotrophic lateral sclerosis (ALS);K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism
3748,100,1,0,9,0,0,2,0,13,0,23,2,"KCNC3;potassium voltage-gated channel, Shaw-related subfamily, member 3",GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0030673//axolemma;GO:0031594//neuromuscular junction;GO:0008076//voltage-gated potassium channel complex;GO:0032590//dendrite membrane;GO:0043679//axon terminus,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0008219//cell death;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization;GO:0046928//regulation of neurotransmitter secretion,GO:0005251//delayed rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity,-
374819,1,2,0,4,2,40,12,0,9,0,3,0,"LRRC37A3;leucine rich repeat containing 37, member A3",GO:0016021//integral component of membrane,-,-,K10955//Vibrio cholerae infection;Amoebiasis
374860,0,0,0,0,0,21,91,0,48,0,0,0,ANKRD30B;ankyrin repeat domain 30B,-,-,-,K00907//Gastric acid secretion;Calcium signaling pathway;Focal adhesion;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
374864,2,0,0,0,0,24,43,0,0,0,10,0,CCDC178;coiled-coil domain containing 178,-,-,-,K04514//Shigellosis;TGF-beta signaling pathway;Leukocyte transendothelial migration;Salmonella infection;Chemokine signaling pathway;Axon guidance;Focal adhesion;Pathogenic Escherichia coli infection;Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
374868,0,0,0,0,0,63,0,76,52,21,0,0,"ATP9B;ATPase, class II, type 9B",GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005802//trans-Golgi network,GO:0045332//phospholipid translocation;GO:0008152//metabolic process;GO:0072600//establishment of protein localization to Golgi,GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,K01530//Purine metabolism
374872,0,0,0,0,0,28,24,0,15,0,0,248,C19orf35;chromosome 19 open reading frame 35,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
374875,0,52,96,0,0,0,0,1,11,0,12,305,HSD11B1L;hydroxysteroid (11-beta) dehydrogenase 1-like,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K15680//Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis
374877,0,0,0,0,0,0,0,0,14,0,0,278,C19orf45;chromosome 19 open reading frame 45,-,-,-,-
374879,0,23,0,0,26,0,0,0,12,0,0,0,ZNF699;zinc finger protein 699,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
374882,0,37,30,13,22,47,0,0,60,0,38,0,TMEM205;transmembrane protein 205,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,K07884//Pancreatic secretion
374897,0,0,0,0,0,0,19,0,48,0,0,0,SBSN;suprabasin,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,-,-
374899,33,20,18,0,0,0,1,43,33,0,0,0,ZNF829;zinc finger protein 829,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
3749,0,0,0,0,24,11,25,32,25,57,0,0,"KCNC4;potassium voltage-gated channel, Shaw-related subfamily, member 4",GO:0043679//axon terminus;GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane;GO:0031594//neuromuscular junction,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport;GO:0046928//regulation of neurotransmitter secretion,GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity;GO:0005249//voltage-gated potassium channel activity,-
374900,17,20,0,1,41,15,37,67,54,0,15,0,ZNF568;zinc finger protein 568,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
374907,101,0,0,0,7,0,0,1,8,27,12,0,"B3GNT8;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0030311//poly-N-acetyllactosamine biosynthetic process;GO:0044267//cellular protein metabolic process,GO:0016262//protein N-acetylglucosaminyltransferase activity;GO:0008378//galactosyltransferase activity,-
374918,0,0,0,0,0,0,0,0,16,0,0,0,IGFL1;IGF-like family member 1,GO:0005615//extracellular space,-,GO:0005515//protein binding,-
374920,1,0,0,0,0,0,0,0,11,0,2,0,C19orf68;chromosome 19 open reading frame 68,GO:0005634//nucleus,GO:0002244//hematopoietic progenitor cell differentiation;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0005515//protein binding,K09187//Lysine degradation
374928,174,9,0,20,0,0,23,0,45,0,0,0,ZNF773;zinc finger protein 773,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
374946,0,0,0,0,0,0,0,18,4,0,0,0,DRAXIN;dorsal inhibitory axon guidance protein,GO:0005576//extracellular region,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0030900//forebrain development;GO:0021516//dorsal spinal cord development;GO:0007411//axon guidance;GO:0030517//negative regulation of axon extension;GO:0043524//negative regulation of neuron apoptotic process;GO:0021528//commissural neuron differentiation in spinal cord;GO:0016055//Wnt signaling pathway,-,-
374955,104,0,32,0,0,43,16,0,0,154,0,0,SPATA21;spermatogenesis associated 21,-,-,GO:0005509//calcium ion binding,K02183//Phototransduction;Insulin signaling pathway;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Long-term potentiation;Pertussis;Tuberculosis;Alcoholism;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Alzheimer's disease;Neurotrophin signaling pathway;Melanogenesis;Gastric acid secretion;Glioma;K10840//Nucleotide excision repair;K12042//Calcium signaling pathway;K05865//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Calcium signaling pathway;Cardiac muscle contraction
374969,0,51,53,57,90,0,0,0,11,0,133,0,CCDC23;coiled-coil domain containing 23,GO:0045177//apical part of cell,GO:0010596//negative regulation of endothelial cell migration;GO:0031397//negative regulation of protein ubiquitination;GO:0009306//protein secretion,-,-
374973,0,0,2,0,0,0,0,0,0,0,0,0,TEX38;testis expressed 38,GO:0016021//integral component of membrane,-,-,-
374986,0,0,0,16,8,1,0,0,43,0,11,0,"FAM73A;family with sequence similarity 73, member A",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
374987,0,0,0,0,0,0,0,0,3,0,6,0,NEXN-AS1;NEXN antisense RNA 1,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
375,0,168,3,55,185,0,0,0,33,0,7,0,ARF1;ADP-ribosylation factor 1,GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0048471//perinuclear region of cytoplasm;GO:0030017//sarcomere,"GO:0006661//phosphatidylinositol biosynthetic process;GO:0050690//regulation of defense response to virus by virus;GO:0061024//membrane organization;GO:0060292//long term synaptic depression;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006644//phospholipid metabolic process;GO:0006878//cellular copper ion homeostasis;GO:0016032//viral process;GO:0015031//protein transport;GO:0006184//GTP catabolic process;GO:0006892//post-Golgi vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle;GO:0044281//small molecule metabolic process;GO:0002090//regulation of receptor internalization;GO:0007264//small GTPase mediated signal transduction",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005057//receptor signaling protein activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K07937//Vibrio cholerae infection;Legionellosis
3750,0,0,0,0,0,0,0,0,77,0,11,0,"KCND1;potassium voltage-gated channel, Shal-related subfamily, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0043025//neuronal cell body;GO:0030425//dendrite;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0051260//protein homooligomerization,GO:0005251//delayed rectifier potassium channel activity;GO:0046872//metal ion binding,-
375033,0,0,0,0,0,16,53,49,47,0,0,0,PEAR1;platelet endothelial aggregation receptor 1,GO:0016021//integral component of membrane;GO:0001891//phagocytic cup,GO:0043654//recognition of apoptotic cell,-,K06252//Focal adhesion;ECM-receptor interaction
375035,151,0,0,0,0,25,0,0,0,15,0,0,SFT2D2;SFT2 domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0016192//vesicle-mediated transport,-,-
375056,177,0,0,22,0,13,19,0,48,0,0,0,"MIA3;melanoma inhibitory activity family, member 3",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0042060//wound healing;GO:0007162//negative regulation of cell adhesion;GO:0006887//exocytosis;GO:0030199//collagen fibril organization;GO:0015031//protein transport;GO:0002063//chondrocyte development;GO:0030336//negative regulation of cell migration;GO:0002687//positive regulation of leukocyte migration;GO:0030501//positive regulation of bone mineralization,GO:0005515//protein binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
375057,0,0,0,0,0,0,0,0,13,0,4,0,C1orf95;chromosome 1 open reading frame 95,GO:0016021//integral component of membrane,-,-,-
375061,0,0,0,0,0,6,1,0,18,0,0,0,"FAM89A;family with sequence similarity 89, member A",-,-,-,-
3751,0,0,0,0,0,0,23,0,62,0,5,1,"KCND2;potassium voltage-gated channel, Shal-related subfamily, member 2",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0043197//dendritic spine,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0001508//action potential;GO:0051260//protein homooligomerization,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,K04892//Serotonergic synapse
375133,0,1,33,0,9,0,1,0,19,0,1,0,"PI4KAP2;phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2",-,GO:0046854//phosphatidylinositol phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling,"GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0016301//kinase activity",K00888//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
375189,0,0,0,0,0,14,0,0,6,0,0,0,"PFN4;profilin family, member 4",GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0030036//actin cytoskeleton organization,GO:0008289//lipid binding;GO:0003779//actin binding,K05759//Regulation of actin cytoskeleton;Salmonella infection;Shigellosis
375190,0,0,1,0,0,19,0,1,12,0,0,0,"FAM228B;family with sequence similarity 228, member B",-,-,-,K10133//p53 signaling pathway
375196,0,0,0,0,0,0,0,165,0,0,0,0,LOC375196;uncharacterized LOC375196,-,-,-,-
3752,0,17,33,0,11,0,5,52,27,0,0,0,"KCND3;potassium voltage-gated channel, Shal-related subfamily, member 3",GO:0008076//voltage-gated potassium channel complex;GO:0097038//perinuclear endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0030425//dendrite;GO:0042383//sarcolemma;GO:0005886//plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0086009//membrane repolarization;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization;GO:0008219//cell death;GO:0071435//potassium ion export,GO:0044325//ion channel binding;GO:0046872//metal ion binding;GO:0005250//A-type (transient outward) potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,-
375248,75,0,0,0,0,29,70,8,46,0,4,4,ANKRD36;ankyrin repeat domain 36,-,-,-,K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
375260,15,0,0,0,11,19,0,53,22,0,0,15,WASH2P;WAS protein family homolog 2 pseudogene,-,-,-,K12495//Endocytosis
375287,0,0,0,3,11,0,26,0,60,0,0,0,RBM43;RNA binding motif protein 43,-,-,GO:0003723//RNA binding;GO:0000166//nucleotide binding,K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
375298,0,0,0,0,0,24,1,0,1,0,0,0,CERKL;ceramide kinase-like,GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0043066//negative regulation of apoptotic process,GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity,K04715//Sphingolipid metabolism
3753,0,0,0,0,0,0,27,0,53,0,11,0,"KCNE1;potassium voltage-gated channel, Isk-related family, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0005764//lysosome;GO:0030018//Z disc;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0006493//protein O-linked glycosylation;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:0086011//membrane repolarization during action potential;GO:0071320//cellular response to cAMP;GO:1901379//regulation of potassium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0006487//protein N-linked glycosylation;GO:0086009//membrane repolarization;GO:0071435//potassium ion export;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0007605//sensory perception of sound;GO:0086013//membrane repolarization during cardiac muscle cell action potential,GO:0005515//protein binding;GO:0015459//potassium channel regulator activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0031433//telethonin binding;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization,-
375307,0,0,0,8,17,0,50,0,5,0,16,10,CATIP;ciliogenesis associated TTC17 interacting protein,GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030041//actin filament polymerization;GO:0044782//cilium organization,GO:0005515//protein binding,-
375316,0,0,0,0,0,17,13,0,17,0,10,0,RBM44;RNA binding motif protein 44,GO:0005737//cytoplasm;GO:0045171//intercellular bridge,-,GO:0000166//nucleotide binding;GO:0042803//protein homodimerization activity;GO:0003723//RNA binding,-
375318,0,0,0,0,0,15,0,0,31,0,0,0,AQP12A;aquaporin 12A,GO:0016021//integral component of membrane,GO:0006810//transport,GO:0005215//transporter activity,-
375323,0,0,0,0,0,0,0,59,0,0,0,0,LHFPL4;lipoma HMGIC fusion partner-like 4,GO:0016021//integral component of membrane,-,-,-
375337,44,0,0,0,0,48,0,1,93,0,11,0,TOPAZ1;testis and ovary specific PAZ domain containing 1,GO:0005829//cytosol,-,GO:0046872//metal ion binding,-
375341,0,0,0,12,21,0,38,0,9,0,0,0,C3orf62;chromosome 3 open reading frame 62,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
375346,0,0,0,0,3,0,20,0,0,0,0,0,TMEM110;transmembrane protein 110,GO:0016021//integral component of membrane,-,-,-
375387,2,0,0,0,0,0,0,0,27,0,0,0,NRROS;negative regulator of reactive oxygen species,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006954//inflammatory response;GO:0006955//immune response;GO:0045087//innate immune response;GO:0006801//superoxide metabolic process,-,-
3754,0,0,0,0,0,0,0,0,0,0,2,0,"KCNF1;potassium voltage-gated channel, subfamily F, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,-
375444,0,0,0,0,0,5,4,0,0,50,0,0,C5orf34;chromosome 5 open reading frame 34,-,-,-,-
375449,74,0,0,0,0,0,0,0,0,0,0,0,MAST4;microtubule associated serine/threonine kinase family member 4,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
375484,0,0,0,0,1,0,59,0,0,97,0,0,SIMC1;SUMO-interacting motifs containing 1,-,-,GO:0032184//SUMO polymer binding,-
3755,0,0,0,0,0,0,0,78,22,37,5,0,"KCNG1;potassium voltage-gated channel, subfamily G, member 1",GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity,-
375513,81,0,0,0,0,0,0,0,0,0,25,0,"GUSBP4;glucuronidase, beta pseudogene 4",-,-,-,K01195//Porphyrin and chlorophyll metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Glycosaminoglycan degradation;Starch and sucrose metabolism;Lysosome;Drug metabolism - other enzymes
375519,103,0,0,0,0,0,0,0,9,1,0,0,"GJB7;gap junction protein, beta 7, 25kDa",GO:0016021//integral component of membrane;GO:0005922//connexon complex,GO:0007154//cell communication,-,-
375567,0,0,0,0,0,0,0,0,12,0,0,0,VWC2;von Willebrand factor C domain containing 2,GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0030054//cell junction;GO:0045202//synapse;GO:0005614//interstitial matrix;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0030514//negative regulation of BMP signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0010811//positive regulation of cell-substrate adhesion,-,K04657//TGF-beta signaling pathway;K04659//Malaria;ECM-receptor interaction;Phagosome;p53 signaling pathway;Bladder cancer;TGF-beta signaling pathway;Focal adhesion;K13908//Salivary secretion
3756,0,0,0,0,0,0,1,0,105,0,0,390,"KCNH1;potassium voltage-gated channel, subfamily H (eag-related), member 1",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane;GO:0005637//nuclear inner membrane,GO:0023014//signal transduction by phosphorylation;GO:0007520//myoblast fusion;GO:0006813//potassium ion transport;GO:0042391//regulation of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0000160//phosphorelay signal transduction system;GO:0071805//potassium ion transmembrane transport,GO:0000155//phosphorelay sensor kinase activity;GO:0005516//calmodulin binding;GO:0005251//delayed rectifier potassium channel activity;GO:0005515//protein binding,-
375607,0,0,0,0,0,0,37,0,26,0,0,0,"NAT16;N-acetyltransferase 16 (GCN5-related, putative)",-,GO:0008152//metabolic process,GO:0008080//N-acetyltransferase activity,-
375611,69,0,0,0,0,10,20,91,47,186,8,0,"SLC26A5;solute carrier family 26 (anion exchanger), member 5",GO:0016328//lateral plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0008360//regulation of cell shape;GO:0042391//regulation of membrane potential;GO:0007605//sensory perception of sound;GO:1902358//sulfate transmembrane transport,GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0030507//spectrin binding,-
375612,0,0,0,1,0,0,19,0,16,0,0,303,LHFPL3;lipoma HMGIC fusion partner-like 3,GO:0016021//integral component of membrane,-,-,-
375616,0,0,1,0,0,64,40,69,7,285,0,0,KCP;kielin/chordin-like protein,GO:0005576//extracellular region,-,-,K04657//TGF-beta signaling pathway;K03900//Focal adhesion;Complement and coagulation cascades;ECM-receptor interaction
375686,0,0,0,9,0,0,0,1,19,0,1,0,SPATC1;spermatogenesis and centriole associated 1,GO:0005737//cytoplasm;GO:0005813//centrosome,-,GO:0043015//gamma-tubulin binding,K10955//Amoebiasis;Vibrio cholerae infection;K01469//Glutathione metabolism
3757,0,0,0,0,0,0,19,41,61,0,5,0,"KCNH2;potassium voltage-gated channel, subfamily H (eag-related), member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0003064//regulation of heart rate by hormone;GO:0086011//membrane repolarization during action potential;GO:1901379//regulation of potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0023014//signal transduction by phosphorylation;GO:0071435//potassium ion export;GO:0035690//cellular response to drug;GO:0000160//phosphorelay signal transduction system;GO:0071805//potassium ion transmembrane transport;GO:0055075//potassium ion homeostasis;GO:0060306//regulation of membrane repolarization;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:1902303//negative regulation of potassium ion export;GO:0086010//membrane depolarization during action potential;GO:0060048//cardiac muscle contraction;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0086005//ventricular cardiac muscle cell action potential,GO:0005251//delayed rectifier potassium channel activity;GO:0000155//phosphorelay sensor kinase activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005249//voltage-gated potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding,-
375704,0,0,0,1,0,0,0,20,5,0,0,0,ENHO;energy homeostasis associated,GO:0005576//extracellular region,-,-,-
375719,0,0,0,0,0,18,0,0,7,0,3,0,AQP7P1;aquaporin 7 pseudogene 1,-,-,-,K08771//PPAR signaling pathway
375743,0,36,0,83,117,38,22,0,82,0,0,0,PTAR1;protein prenyltransferase alpha subunit repeat containing 1,-,GO:0018342//protein prenylation,GO:0008318//protein prenyltransferase activity,-
375748,109,37,2,33,87,40,42,0,88,29,111,0,ERCC6L2;excision repair cross-complementation group 6-like 2,GO:0005739//mitochondrion;GO:0005815//microtubule organizing center;GO:0005634//nucleus,GO:0006281//DNA repair;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0008026//ATP-dependent helicase activity,K10841//Nucleotide excision repair
375757,95,0,0,0,2,0,16,0,11,0,0,0,SWI5;SWI5 recombination repair homolog (yeast),GO:0032798//Swi5-Sfr1 complex;GO:0005634//nucleus,GO:0071479//cellular response to ionizing radiation;GO:0000724//double-strand break repair via homologous recombination,GO:0005515//protein binding,-
375759,0,0,0,0,0,0,0,0,20,0,11,0,C9orf50;chromosome 9 open reading frame 50,-,-,-,-
375775,96,0,4,7,13,17,76,62,35,0,18,2,PNPLA7;patatin-like phospholipase domain containing 7,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005765//lysosomal membrane;GO:0031965//nuclear membrane,GO:0006629//lipid metabolic process,GO:0004622//lysophospholipase activity,K14676//Glycerophospholipid metabolism
375790,0,0,0,0,0,7,0,235,98,0,9,0,AGRN;agrin,GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0030054//cell junction;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005605//basal lamina;GO:0005737//cytoplasm;GO:0043202//lysosomal lumen,"GO:0030203//glycosaminoglycan metabolic process;GO:0007165//signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0051491//positive regulation of filopodium assembly;GO:0005975//carbohydrate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045213//neurotransmitter receptor metabolic process;GO:0045162//clustering of voltage-gated sodium channels;GO:0007528//neuromuscular junction development;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0006024//glycosaminoglycan biosynthetic process;GO:0010469//regulation of receptor activity;GO:0044281//small molecule metabolic process;GO:0043113//receptor clustering;GO:0001523//retinoid metabolic process;GO:0030198//extracellular matrix organization;GO:0050808//synapse organization;GO:0007411//axon guidance;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0045887//positive regulation of synaptic growth at neuromuscular junction;GO:0043525//positive regulation of neuron apoptotic process;GO:0007603//phototransduction, visible light;GO:0007009//plasma membrane organization",GO:0030548//acetylcholine receptor regulator activity;GO:0005509//calcium ion binding;GO:0035374//chondroitin sulfate binding;GO:0005515//protein binding;GO:0043236//laminin binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0005200//structural constituent of cytoskeleton;GO:0033691//sialic acid binding;GO:0002162//dystroglycan binding,K06254//ECM-receptor interaction
3758,0,0,0,0,0,0,0,15,0,0,0,0,"KCNJ1;potassium inwardly-rectifying channel, subfamily J, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport;GO:0007588//excretion;GO:0070294//renal sodium ion absorption;GO:0009791//post-embryonic development;GO:0001822//kidney development;GO:1900128//regulation of G-protein activated inward rectifier potassium channel activity;GO:0001894//tissue homeostasis;GO:0072358//cardiovascular system development,"GO:0005524//ATP binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005242//inward rectifier potassium channel activity",K04995//Gastric acid secretion;Aldosterone-regulated sodium reabsorption
3759,0,0,0,0,0,23,0,0,0,0,0,0,"KCNJ2;potassium inwardly-rectifying channel, subfamily J, member 2",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0014704//intercalated disc;GO:0030315//T-tubule;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0031224//intrinsic component of membrane;GO:0005791//rough endoplasmic reticulum;GO:0005790//smooth endoplasmic reticulum;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane,GO:0014861//regulation of skeletal muscle contraction via regulation of action potential;GO:0030007//cellular potassium ion homeostasis;GO:0060075//regulation of resting membrane potential;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086011//membrane repolarization during action potential;GO:0071260//cellular response to mechanical stimulus;GO:0007268//synaptic transmission;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0010107//potassium ion import;GO:0051289//protein homotetramerization;GO:0090076//relaxation of skeletal muscle;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0015693//magnesium ion transport;GO:0006813//potassium ion transport;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0055119//relaxation of cardiac muscle;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0060306//regulation of membrane repolarization,"GO:0042802//identical protein binding;GO:0005242//inward rectifier potassium channel activity;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K04996//Gastric acid secretion;Cholinergic synapse
375940,0,0,0,0,0,0,0,0,33,0,0,0,DMBT1P1;deleted in malignant brain tumors 1 pseudogene 1,-,-,-,K13912//Salivary secretion
3760,0,0,0,0,0,14,0,0,16,0,3,0,"KCNJ3;potassium inwardly-rectifying channel, subfamily J, member 3",GO:0008076//voltage-gated potassium channel complex;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,GO:0051602//response to electrical stimulus;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport,GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity,K04997//Retrograde endocannabinoid signaling;Serotonergic synapse;Morphine addiction;Cholinergic synapse;Dopaminergic synapse;Glutamatergic synapse
3761,0,0,0,0,0,0,0,0,17,0,0,0,"KCNJ4;potassium inwardly-rectifying channel, subfamily J, member 4",GO:0008076//voltage-gated potassium channel complex;GO:0030659//cytoplasmic vesicle membrane;GO:0016323//basolateral plasma membrane;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport,GO:0005242//inward rectifier potassium channel activity;GO:0030165//PDZ domain binding;GO:0005515//protein binding,K04998//Cholinergic synapse
376132,23,0,0,0,0,0,0,0,9,0,0,0,LRRC10;leucine rich repeat containing 10,GO:0005739//mitochondrion;GO:0030017//sarcomere;GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:0055013//cardiac muscle cell development,GO:0003779//actin binding;GO:0051393//alpha-actinin binding,K12796//NOD-like receptor signaling pathway;K10130//p53 signaling pathway;NF-kappa B signaling pathway
3762,0,0,0,0,0,0,0,0,21,0,0,0,"KCNJ5;potassium inwardly-rectifying channel, subfamily J, member 5",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0006813//potassium ion transport,GO:0005515//protein binding;GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity,K04999//Retrograde endocannabinoid signaling;Serotonergic synapse;Morphine addiction;Dopaminergic synapse
376267,12,47,0,8,43,14,0,48,26,0,27,519,"RAB15;RAB15, member RAS oncogene family",GO:0072372//primary cilium;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005515//protein binding;GO:0005525//GTP binding,-
3763,0,0,0,0,0,27,0,0,13,0,12,0,"KCNJ6;potassium inwardly-rectifying channel, subfamily J, member 6",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0008076//voltage-gated potassium channel complex,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport,GO:0015467//G-protein activated inward rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0005515//protein binding,K05000//Serotonergic synapse;Retrograde endocannabinoid signaling;GABAergic synapse;Dopaminergic synapse;Cholinergic synapse;Morphine addiction
3764,91,0,0,0,0,0,0,0,20,0,0,0,"KCNJ8;potassium inwardly-rectifying channel, subfamily J, member 8",GO:0005739//mitochondrion;GO:0042383//sarcolemma;GO:0030016//myofibril;GO:0005886//plasma membrane;GO:0008282//ATP-sensitive potassium channel complex;GO:0008076//voltage-gated potassium channel complex,GO:0042311//vasodilation;GO:0006813//potassium ion transport;GO:0043330//response to exogenous dsRNA;GO:0032496//response to lipopolysaccharide;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0010107//potassium ion import;GO:0051607//defense response to virus;GO:0009268//response to pH;GO:0001822//kidney development;GO:0007507//heart development,GO:0005242//inward rectifier potassium channel activity;GO:0017098//sulfonylurea receptor binding;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0005524//ATP binding,-
376412,0,0,2,0,0,0,0,0,0,0,0,0,RNF126P1;ring finger protein 126 pseudogene 1,-,-,-,-
376497,0,0,0,0,40,0,0,56,20,342,30,0,"SLC27A1;solute carrier family 27 (fatty acid transporter), member 1",GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0044255//cellular lipid metabolic process;GO:0001579//medium-chain fatty acid transport;GO:0033211//adiponectin-activated signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0009409//response to cold;GO:0006656//phosphatidylcholine biosynthetic process;GO:0055085//transmembrane transport;GO:0006631//fatty acid metabolic process;GO:0015909//long-chain fatty acid transport;GO:0006659//phosphatidylserine biosynthetic process;GO:0071072//negative regulation of phospholipid biosynthetic process;GO:0031652//positive regulation of heat generation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0032049//cardiolipin biosynthetic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process,GO:0031957//very long-chain fatty acid-CoA ligase activity;GO:0015245//fatty acid transporter activity;GO:0000166//nucleotide binding;GO:0042803//protein homodimerization activity,K08745//PPAR signaling pathway;Fat digestion and absorption
3766,1,0,0,0,0,35,10,59,19,0,23,0,"KCNJ10;potassium inwardly-rectifying channel, subfamily J, member 10",GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex,GO:0060075//regulation of resting membrane potential;GO:0006954//inflammatory response;GO:0022010//central nervous system myelination;GO:0007601//visual perception;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0051930//regulation of sensory perception of pain;GO:0051935//L-glutamate uptake involved in synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0051289//protein homotetramerization;GO:0010107//potassium ion import;GO:0060081//membrane hyperpolarization;GO:0051384//response to glucocorticoid;GO:0006813//potassium ion transport;GO:0009637//response to blue light;GO:0051385//response to mineralocorticoid;GO:0007628//adult walking behavior;GO:0055075//potassium ion homeostasis;GO:0021554//optic nerve development,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0005102//receptor binding;GO:0015272//ATP-activated inward rectifier potassium channel activity;GO:0005524//ATP binding,K05003//Gastric acid secretion
376693,0,0,0,1,0,0,7,0,0,0,0,0,RPS10P7;ribosomal protein S10 pseudogene 7,-,-,-,K02947//Ribosome
3767,3,0,0,0,0,0,3,0,18,119,0,0,"KCNJ11;potassium inwardly-rectifying channel, subfamily J, member 11",GO:0043025//neuronal cell body;GO:0043209//myelin sheath;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0005768//endosome;GO:0030315//T-tubule;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0008282//ATP-sensitive potassium channel complex;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane;GO:0030673//axolemma;GO:0005739//mitochondrion;GO:0070852//cell body fiber;GO:0005829//cytosol,GO:0042493//response to drug;GO:0010107//potassium ion import;GO:0050877//neurological system process;GO:0033198//response to ATP;GO:0044281//small molecule metabolic process;GO:0002931//response to ischemia;GO:0033574//response to testosterone;GO:0050796//regulation of insulin secretion;GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0006006//glucose metabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0032355//response to estradiol;GO:2001259//positive regulation of cation channel activity;GO:0006112//energy reserve metabolic process;GO:0071333//cellular response to glucose stimulus;GO:0046676//negative regulation of insulin secretion;GO:0071316//cellular response to nicotine;GO:0007268//synaptic transmission,GO:0030955//potassium ion binding;GO:0030506//ankyrin binding;GO:0005524//ATP binding;GO:0005249//voltage-gated potassium channel activity;GO:0031072//heat shock protein binding;GO:0044325//ion channel binding;GO:0008022//protein C-terminus binding;GO:0015272//ATP-activated inward rectifier potassium channel activity,K05004//Type II diabetes mellitus
3768,0,0,0,0,0,0,0,0,4,0,0,0,"KCNJ12;potassium inwardly-rectifying channel, subfamily J, member 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0031224//intrinsic component of membrane,GO:0008016//regulation of heart contraction;GO:0051289//protein homotetramerization;GO:0006813//potassium ion transport;GO:0006936//muscle contraction;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005242//inward rectifier potassium channel activity,K05005//Cholinergic synapse
376844,0,0,0,0,0,0,0,0,5,0,0,0,SDC4P;syndecan 4 pseudogene,-,-,-,K06257//ECM-receptor interaction;Malaria;Cell adhesion molecules (CAMs)
3769,0,1,26,23,0,0,0,0,47,0,0,0,"KCNJ13;potassium inwardly-rectifying channel, subfamily J, member 13",GO:0016021//integral component of membrane,GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005242//inward rectifier potassium channel activity,K05006//Protein digestion and absorption
376940,72,1,0,22,39,35,15,0,44,324,11,1,ZC3H6;zinc finger CCCH-type containing 6,-,-,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer
377,0,33,1,18,165,13,0,0,61,0,10,0,ARF3;ADP-ribosylation factor 3,GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0048471//perinuclear region of cytoplasm,GO:0044281//small molecule metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0016192//vesicle-mediated transport;GO:0006644//phospholipid metabolic process;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity,-
3770,203,0,16,0,0,0,72,0,9,0,13,0,"KCNJ14;potassium inwardly-rectifying channel, subfamily J, member 14",GO:0043025//neuronal cell body;GO:0008076//voltage-gated potassium channel complex;GO:0030425//dendrite;GO:0005886//plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005242//inward rectifier potassium channel activity,K05007//Cholinergic synapse
377007,0,0,0,0,0,0,0,0,65,0,0,0,KLHL30;kelch-like family member 30,-,-,-,-
377047,0,0,0,0,0,0,12,0,6,0,0,0,"PRSS45;protease, serine, 45",-,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
3772,0,0,0,0,0,0,0,124,5,1,0,0,"KCNJ15;potassium inwardly-rectifying channel, subfamily J, member 15",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport,GO:0005242//inward rectifier potassium channel activity;GO:0005515//protein binding,K05008//Gastric acid secretion
3773,0,0,0,1,0,5,0,0,2,0,0,0,"KCNJ16;potassium inwardly-rectifying channel, subfamily J, member 16",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport,GO:0005242//inward rectifier potassium channel activity,K05009//Gastric acid secretion
3775,0,0,0,6,0,0,0,0,34,0,12,0,"KCNK1;potassium channel, subfamily K, member 1",GO:0008076//voltage-gated potassium channel complex;GO:0016324//apical plasma membrane;GO:0005768//endosome;GO:0031526//brush border membrane;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0035094//response to nicotine;GO:0006813//potassium ion transport,GO:0005242//inward rectifier potassium channel activity,-
3776,92,0,0,0,0,0,0,0,71,0,0,115,"KCNK2;potassium channel, subfamily K, member 2",GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0008076//voltage-gated potassium channel complex,GO:0042391//regulation of membrane potential;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0007186//G-protein coupled receptor signaling pathway,GO:0022841//potassium ion leak channel activity;GO:0019870//potassium channel inhibitor activity;GO:0015271//outward rectifier potassium channel activity,K04913//Gastric acid secretion
377630,1,0,0,0,0,1,0,0,9,1,9,0,USP17L2;ubiquitin specific peptidase 17-like family member 2,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:1900245//positive regulation of MDA-5 signaling pathway;GO:0016579//protein deubiquitination;GO:0090315//negative regulation of protein targeting to membrane;GO:0006511//ubiquitin-dependent protein catabolic process;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0000075//cell cycle checkpoint;GO:0007093//mitotic cell cycle checkpoint;GO:0034261//negative regulation of Ras GTPase activity;GO:0031064//negative regulation of histone deacetylation;GO:0070536//protein K63-linked deubiquitination;GO:0030334//regulation of cell migration;GO:0071586//CAAX-box protein processing;GO:1900027//regulation of ruffle assembly;GO:0050691//regulation of defense response to virus by host;GO:0010955//negative regulation of protein processing;GO:0042127//regulation of cell proliferation;GO:0042981//regulation of apoptotic process;GO:0032321//positive regulation of Rho GTPase activity;GO:0006915//apoptotic process;GO:0071108//protein K48-linked deubiquitination,GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0004221//ubiquitin thiolesterase activity,-
377677,0,0,0,0,0,2,0,0,71,0,0,650,CA13;carbonic anhydrase XIII,GO:0043209//myelin sheath;GO:0005829//cytosol,GO:0006730//one-carbon metabolic process;GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport,GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity,K01672//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Pancreatic secretion;Nitrogen metabolism;Bile secretion;Collecting duct acid secretion
3777,6,0,0,0,1,0,0,1,37,142,8,0,"KCNK3;potassium channel, subfamily K, member 3",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0042493//response to drug;GO:0071456//cellular response to hypoxia;GO:0071294//cellular response to zinc ion;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0007420//brain development;GO:0090102//cochlea development;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005216//ion channel activity;GO:0022841//potassium ion leak channel activity;GO:0044548//S100 protein binding;GO:0005267//potassium channel activity;GO:0005252//open rectifier potassium channel activity;GO:0008022//protein C-terminus binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,-
3778,136,45,0,10,26,9,5,0,109,139,9,184,"KCNMA1;potassium large conductance calcium-activated channel, subfamily M, alpha member 1",GO:0008076//voltage-gated potassium channel complex;GO:0016324//apical plasma membrane;GO:0005901//caveola;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030007//cellular potassium ion homeostasis;GO:0045794//negative regulation of cell volume;GO:0060083//smooth muscle contraction involved in micturition;GO:0006970//response to osmotic stress;GO:0007596//blood coagulation;GO:0060073//micturition;GO:0001666//response to hypoxia;GO:0006813//potassium ion transport;GO:0042391//regulation of membrane potential;GO:0051592//response to calcium ion;GO:0043065//positive regulation of apoptotic process;GO:0034465//response to carbon monoxide;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005249//voltage-gated potassium channel activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0060072//large conductance calcium-activated potassium channel activity;GO:0015269//calcium-activated potassium channel activity,K04936//Vascular smooth muscle contraction;Salivary secretion;Pancreatic secretion
377841,0,0,0,38,78,0,0,0,19,0,29,0,ENTPD8;ectonucleoside triphosphate diphosphohydrolase 8,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0009133//nucleoside diphosphate biosynthetic process;GO:0009124//nucleoside monophosphate biosynthetic process,GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding,K01510//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection
3779,83,0,0,0,0,0,0,0,13,0,0,0,"KCNMB1;potassium large conductance calcium-activated channel, subfamily M, beta member 1",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0051592//response to calcium ion;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0007596//blood coagulation;GO:0006813//potassium ion transport,GO:0015269//calcium-activated potassium channel activity;GO:0015459//potassium channel regulator activity,K04937//Vascular smooth muscle contraction
378,0,38,0,80,283,7,0,0,0,0,0,0,ARF4;ADP-ribosylation factor 4,GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0048678//response to axon injury;GO:0007420//brain development;GO:0015031//protein transport;GO:0043066//negative regulation of apoptotic process;GO:0006471//protein ADP-ribosylation;GO:0031584//activation of phospholipase D activity;GO:0016477//cell migration;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0016192//vesicle-mediated transport;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007264//small GTPase mediated signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0005525//GTP binding;GO:0005154//epidermal growth factor receptor binding,-
3780,0,0,0,0,0,22,0,0,2,0,0,0,"KCNN1;potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1",GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport,GO:0016286//small conductance calcium-activated potassium channel activity;GO:0015269//calcium-activated potassium channel activity;GO:0046982//protein heterodimerization activity;GO:0005516//calmodulin binding,-
3781,0,29,0,1,22,29,0,0,13,0,38,0,"KCNN2;potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2",GO:0030018//Z disc;GO:0043197//dendritic spine;GO:0005790//smooth endoplasmic reticulum;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0005886//plasma membrane,GO:1901379//regulation of potassium ion transmembrane transport;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission,GO:0042803//protein homodimerization activity;GO:0051393//alpha-actinin binding;GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity;GO:0005516//calmodulin binding,K04943//Bile secretion;Serotonergic synapse
3782,32,0,0,0,0,36,49,0,77,227,0,0,"KCNN3;potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission,GO:0016286//small conductance calcium-activated potassium channel activity;GO:0005516//calmodulin binding,-
3783,0,0,0,0,0,0,3,0,13,0,0,0,"KCNN4;potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4",GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0045121//membrane raft,GO:0050714//positive regulation of protein secretion;GO:0006952//defense response;GO:0002376//immune system process;GO:0030322//stabilization of membrane potential;GO:0045332//phospholipid translocation;GO:0046541//saliva secretion;GO:0006813//potassium ion transport;GO:0071435//potassium ion export;GO:0071805//potassium ion transmembrane transport;GO:0006884//cell volume homeostasis;GO:0006816//calcium ion transport;GO:0007268//synaptic transmission;GO:0050862//positive regulation of T cell receptor signaling pathway,GO:0015269//calcium-activated potassium channel activity;GO:0016286//small conductance calcium-activated potassium channel activity;GO:0022894//Intermediate conductance calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0005516//calmodulin binding,K04945//Protein digestion and absorption;Salivary secretion
3784,0,0,0,0,0,32,80,0,30,0,7,0,"KCNQ1;potassium voltage-gated channel, KQT-like subfamily, member 1",GO:0005764//lysosome;GO:0008076//voltage-gated potassium channel complex;GO:0042383//sarcolemma;GO:0016323//basolateral plasma membrane;GO:0042589//zymogen granule membrane;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005770//late endosome,GO:0086005//ventricular cardiac muscle cell action potential;GO:0007605//sensory perception of sound;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0072358//cardiovascular system development;GO:0060048//cardiac muscle contraction;GO:0006349//regulation of gene expression by genetic imprinting;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0086014//atrial cardiac muscle cell action potential;GO:0071805//potassium ion transmembrane transport;GO:0060306//regulation of membrane repolarization;GO:0071435//potassium ion export;GO:0071872//cellular response to epinephrine stimulus;GO:0035690//cellular response to drug;GO:0008016//regulation of heart contraction;GO:0016458//gene silencing;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0046676//negative regulation of insulin secretion;GO:0008584//male gonad development;GO:0007268//synaptic transmission;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0071320//cellular response to cAMP;GO:0060454//positive regulation of gastric acid secretion;GO:0086011//membrane repolarization during action potential,GO:0086089//voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0086008//voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization;GO:0005516//calmodulin binding;GO:0005249//voltage-gated potassium channel activity;GO:0015271//outward rectifier potassium channel activity;GO:0008157//protein phosphatase 1 binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0034237//protein kinase A regulatory subunit binding;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;GO:0097110//scaffold protein binding;GO:0005251//delayed rectifier potassium channel activity;GO:0044325//ion channel binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K04926//Vibrio cholerae infection;Protein digestion and absorption;Gastric acid secretion;Pancreatic secretion;Cholinergic synapse
3785,56,0,0,0,1,27,13,0,34,0,0,0,"KCNQ2;potassium voltage-gated channel, KQT-like subfamily, member 2",GO:0008076//voltage-gated potassium channel complex;GO:0033268//node of Ranvier;GO:0005886//plasma membrane;GO:0043194//axon initial segment,GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0071805//potassium ion transmembrane transport;GO:0019226//transmission of nerve impulse;GO:0006813//potassium ion transport,GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0030506//ankyrin binding,K04927//Cholinergic synapse
3786,0,0,0,0,0,33,0,0,70,0,0,0,"KCNQ3;potassium voltage-gated channel, KQT-like subfamily, member 3",GO:0008076//voltage-gated potassium channel complex;GO:0033268//node of Ranvier;GO:0005886//plasma membrane;GO:0043194//axon initial segment,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0007411//axon guidance;GO:0060081//membrane hyperpolarization;GO:0006813//potassium ion transport,GO:0005249//voltage-gated potassium channel activity;GO:0005267//potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,K04928//Cholinergic synapse
3787,0,0,0,0,0,0,23,37,33,0,16,0,"KCNS1;potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0051260//protein homooligomerization;GO:0006813//potassium ion transport,GO:0015459//potassium channel regulator activity;GO:0005515//protein binding;GO:0005251//delayed rectifier potassium channel activity,-
378708,0,0,0,0,0,0,0,0,0,0,6,0,"APITD1;apoptosis-inducing, TAF9-like domain 1",GO:0000777//condensed chromosome kinetochore;GO:0043240//Fanconi anaemia nuclear complex;GO:0005829//cytosol;GO:0071821//FANCM-MHF complex,GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0000278//mitotic cell cycle;GO:0031398//positive regulation of protein ubiquitination;GO:0031297//replication fork processing;GO:0006974//cellular response to DNA damage stimulus;GO:0000712//resolution of meiotic recombination intermediates,GO:0003690//double-stranded DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11511//Fanconi anemia pathway
3788,1,0,0,0,0,12,0,158,24,0,0,0,"KCNS2;potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0051260//protein homooligomerization;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity,-
378807,0,0,0,0,0,0,0,0,16,0,0,0,"CATSPER4;cation channel, sperm associated 4",GO:0097228//sperm principal piece;GO:0005886//plasma membrane;GO:0036128//CatSper complex;GO:0001669//acrosomal vesicle,GO:0006814//sodium ion transport;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0007338//single fertilization;GO:0032504//multicellular organism reproduction;GO:0048240//sperm capacitation;GO:0070588//calcium ion transmembrane transport;GO:0035036//sperm-egg recognition;GO:0034765//regulation of ion transmembrane transport;GO:0030317//sperm motility;GO:0007275//multicellular organismal development,GO:0005227//calcium activated cation channel activity;GO:0005245//voltage-gated calcium channel activity,-
378825,0,0,0,0,0,10,0,0,9,0,0,0,LINC00162;long intergenic non-protein coding RNA 162,-,-,-,-
378828,0,0,0,0,0,0,25,0,10,0,0,0,LINC00317;long intergenic non-protein coding RNA 317,-,-,-,-
378832,0,0,0,0,0,0,48,0,11,0,0,0,COL18A1-AS1;COL18A1 antisense RNA 1,-,-,-,-
378881,0,0,0,0,0,0,0,42,0,0,0,0,MIR381HG;MIR381 host gene (non-protein coding),-,-,-,-
378884,0,0,0,0,0,0,3,94,9,0,0,0,NHLRC1;NHL repeat containing E3 ubiquitin protein ligase 1,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0000209//protein polyubiquitination;GO:0006914//autophagy;GO:0006006//glucose metabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0005978//glycogen biosynthetic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10602//Ubiquitin mediated proteolysis
378925,0,0,0,0,0,0,0,0,13,0,0,0,RNF148;ring finger protein 148,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
378938,112,23,0,0,8,14,4,0,25,0,0,0,MALAT1;metastasis associated lung adenocarcinoma transcript 1 (non-protein coding),-,-,-,-
379,0,0,0,0,0,0,20,1,8,0,0,0,ARL4D;ADP-ribosylation factor-like 4D,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0009306//protein secretion;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
3790,0,0,0,0,0,0,15,0,0,0,3,0,"KCNS3;potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0008076//voltage-gated potassium channel complex,GO:0051260//protein homooligomerization;GO:0044281//small molecule metabolic process;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport,GO:0015459//potassium channel regulator activity;GO:0005251//delayed rectifier potassium channel activity,-
379013,0,18,6,0,0,11,0,0,11,157,38,0,"RNF138P1;ring finger protein 138, E3 ubiquitin protein ligase pseudogene 1",-,-,-,-
3791,0,0,0,0,0,14,102,0,17,0,2,0,KDR;kinase insert domain receptor (a type III receptor tyrosine kinase),GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045121//membrane raft;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0097443//sorting endosome;GO:0005634//nucleus,GO:0018108//peptidyl-tyrosine phosphorylation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0030335//positive regulation of cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:0048286//lung alveolus development;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0045446//endothelial cell differentiation;GO:0001570//vasculogenesis;GO:0045165//cell fate commitment;GO:0045766//positive regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001541//ovarian follicle development;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0046777//protein autophosphorylation;GO:0055074//calcium ion homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0008360//regulation of cell shape;GO:0001945//lymph vessel development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0010595//positive regulation of endothelial cell migration;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0003158//endothelium development;GO:0001525//angiogenesis;GO:0048469//cell maturation;GO:0043129//surfactant homeostasis;GO:0043410//positive regulation of MAPK cascade;GO:0008284//positive regulation of cell proliferation;GO:0050927//positive regulation of positive chemotaxis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0035162//embryonic hemopoiesis;GO:0023014//signal transduction by phosphorylation;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:2001214//positive regulation of vasculogenesis;GO:0016032//viral process,GO:0051879//Hsp90 protein binding;GO:0005524//ATP binding;GO:0038085//vascular endothelial growth factor binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0019838//growth factor binding,K05098//Focal adhesion;VEGF signaling pathway;Cytokine-cytokine receptor interaction;Endocytosis
3792,29,0,0,0,8,17,0,0,38,0,3,0,"KEL;Kell blood group, metallo-endopeptidase",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0042310//vasoconstriction,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity,-
3795,91,0,0,0,14,0,12,0,25,48,0,297,KHK;ketohexokinase (fructokinase),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006001//fructose catabolic process;GO:0046835//carbohydrate phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0070873//regulation of glycogen metabolic process,GO:0005524//ATP binding;GO:0004454//ketohexokinase activity,K00846//Metabolic pathways;Fructose and mannose metabolism
3796,0,25,0,19,36,0,0,25,48,6,0,0,KIF2A;kinesin heavy chain member 2A,GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0016020//membrane;GO:0000922//spindle pole;GO:0005876//spindle microtubule;GO:0005813//centrosome,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation;GO:0008152//metabolic process;GO:0007399//nervous system development;GO:0007052//mitotic spindle organization;GO:0000278//mitotic cell cycle;GO:0030154//cell differentiation;GO:0007019//microtubule depolymerization;GO:0007018//microtubule-based movement;GO:0006200//ATP catabolic process;GO:0007067//mitotic nuclear division,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0003774//motor activity,-
3797,127,21,0,6,1,46,0,0,14,52,7,0,KIF3C;kinesin family member 3C,GO:0005874//microtubule;GO:0005829//cytosol;GO:0005871//kinesin complex,GO:0030705//cytoskeleton-dependent intracellular transport;GO:0072384//organelle transport along microtubule;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
3798,0,0,0,0,0,8,66,28,86,0,0,0,KIF5A;kinesin family member 5A,GO:0048471//perinuclear region of cytoplasm;GO:0005874//microtubule;GO:0016020//membrane;GO:0005829//cytosol;GO:0005871//kinesin complex,GO:0006200//ATP catabolic process;GO:0008219//cell death;GO:0007018//microtubule-based movement;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0008104//protein localization;GO:0007411//axon guidance;GO:0007268//synaptic transmission;GO:0008152//metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation,GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003774//motor activity;GO:0016887//ATPase activity,K10396//Dopaminergic synapse
3799,0,212,3,52,443,31,0,46,32,245,5,0,KIF5B;kinesin family member 5B,GO:0048471//perinuclear region of cytoplasm;GO:0005815//microtubule organizing center;GO:0005874//microtubule;GO:0030139//endocytic vesicle;GO:0005871//kinesin complex;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0035253//ciliary rootlet;GO:0016020//membrane;GO:0043005//neuron projection,GO:0030705//cytoskeleton-dependent intracellular transport;GO:0007018//microtubule-based movement;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0035617//stress granule disassembly;GO:0006200//ATP catabolic process;GO:0007028//cytoplasm organization;GO:0007411//axon guidance;GO:0043268//positive regulation of potassium ion transport;GO:0047496//vesicle transport along microtubule;GO:0044267//cellular protein metabolic process;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0042391//regulation of membrane potential,GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0016887//ATPase activity;GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding,K10396//Dopaminergic synapse
38,0,40,0,21,150,0,5,0,7,0,11,0,ACAT1;acetyl-CoA acetyltransferase 1,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0060612//adipose tissue development;GO:0034641//cellular nitrogen compound metabolic process;GO:0007420//brain development;GO:0009083//branched-chain amino acid catabolic process;GO:0042594//response to starvation;GO:0001889//liver development;GO:0044281//small molecule metabolic process;GO:0009725//response to hormone;GO:0046951//ketone body biosynthetic process;GO:0051260//protein homooligomerization;GO:0044255//cellular lipid metabolic process;GO:0072229//metanephric proximal convoluted tubule development;GO:0014070//response to organic cyclic compound;GO:0046952//ketone body catabolic process,GO:0019899//enzyme binding;GO:0003985//acetyl-CoA C-acetyltransferase activity;GO:0050662//coenzyme binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding,"K00626//Valine, leucine and isoleucine degradation;Fat digestion and absorption;Carbon fixation pathways in prokaryotes;Butanoate metabolism;Fatty acid metabolism;Lysine degradation;Two-component system;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;Propanoate metabolism;Pyruvate metabolism;Synthesis and degradation of ketone bodies;Biosynthesis of secondary metabolites;Tryptophan metabolism;Benzoate degradation;Terpenoid backbone biosynthesis;Microbial metabolism in diverse environments"
3800,0,41,1,46,276,8,0,0,31,0,11,0,KIF5C;kinesin family member 5C,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex,GO:0007018//microtubule-based movement;GO:0051028//mRNA transport;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0006200//ATP catabolic process;GO:0006996//organelle organization;GO:0008104//protein localization;GO:0007411//axon guidance;GO:0008152//metabolic process,GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding,K10396//Dopaminergic synapse
3801,79,0,0,8,0,47,10,1,0,0,0,0,KIFC3;kinesin family member C3,GO:0005813//centrosome;GO:0005915//zonula adherens;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0030659//cytoplasmic vesicle membrane;GO:0005871//kinesin complex,GO:0006200//ATP catabolic process;GO:0007601//visual perception;GO:0090136//epithelial cell-cell adhesion;GO:0008152//metabolic process;GO:0007030//Golgi organization;GO:0045218//zonula adherens maintenance;GO:0007018//microtubule-based movement,GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity,-
3802,50,0,0,0,0,0,0,0,1,0,0,0,"KIR2DL1;killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006955//immune response;GO:0050776//regulation of immune response;GO:0002769//natural killer cell inhibitory signaling pathway,GO:0004872//receptor activity;GO:0005515//protein binding,K07982//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;K07981//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease
3803,0,0,0,0,0,0,0,0,16,0,0,0,"KIR2DL2;killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050776//regulation of immune response,-,K07981//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity;K07982//Natural killer cell mediated cytotoxicity;Antigen processing and presentation
3804,0,0,0,0,0,0,0,0,0,0,1,0,"KIR2DL3;killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3",GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006955//immune response;GO:0050776//regulation of immune response,GO:0005515//protein binding;GO:0003823//antigen binding;GO:0004872//receptor activity,K07980//Graft-versus-host disease;Natural killer cell mediated cytotoxicity;Antigen processing and presentation;K07981//Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Antigen processing and presentation
3805,0,0,0,0,0,0,0,1,13,0,0,330,"KIR2DL4;killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006968//cellular defense response;GO:0050776//regulation of immune response;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K07981//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
3806,5,0,0,0,0,0,0,0,0,0,0,0,"KIR2DS1;killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0050776//regulation of immune response;GO:0045087//innate immune response;GO:0006955//immune response,GO:0004888//transmembrane signaling receptor activity,K07981//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;K07982//Antigen processing and presentation;Natural killer cell mediated cytotoxicity
3809,0,0,0,0,0,0,0,0,35,0,0,0,"KIR2DS4;killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0045087//innate immune response,-,K07981//Graft-versus-host disease;Natural killer cell mediated cytotoxicity;Antigen processing and presentation;K07982//Natural killer cell mediated cytotoxicity;Antigen processing and presentation
381,0,29,3,0,10,0,0,0,0,0,1,0,ARF5;ADP-ribosylation factor 5,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
3810,0,0,0,0,0,0,0,0,8,0,0,0,"KIR2DS5;killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0045087//innate immune response;GO:0006955//immune response;GO:0007165//signal transduction,GO:0030110//HLA-C specific inhibitory MHC class I receptor activity,K07982//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;K07981//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
3811,0,0,0,0,0,0,0,0,8,105,5,0,"KIR3DL1;killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0006955//immune response;GO:0007165//signal transduction,GO:0030109//HLA-B specific inhibitory MHC class I receptor activity,K07980//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
3813,0,0,0,0,0,0,6,0,0,0,0,0,"KIR3DS1;killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0045087//innate immune response;GO:0006955//immune response;GO:0007165//signal transduction;GO:0030101//natural killer cell activation,GO:0032393//MHC class I receptor activity,K07980//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity
3814,0,0,0,0,0,6,0,0,0,0,0,0,KISS1;KiSS-1 metastasis-suppressor,GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0043410//positive regulation of MAPK cascade;GO:0060112//generation of ovulation cycle rhythm;GO:0060124//positive regulation of growth hormone secretion;GO:0050806//positive regulation of synaptic transmission;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0033686//positive regulation of luteinizing hormone secretion;GO:0007010//cytoskeleton organization;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding;GO:0031773//kisspeptin receptor binding,-
3815,0,0,0,0,0,14,0,0,67,0,0,0,KIT;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog,GO:0001669//acrosomal vesicle;GO:0005615//extracellular space;GO:0042629//mast cell granule;GO:0005911//cell-cell junction;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0016021//integral component of membrane,GO:0002327//immature B cell differentiation;GO:0001541//ovarian follicle development;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0019221//cytokine-mediated signaling pathway;GO:0031274//positive regulation of pseudopodium assembly;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006687//glycosphingolipid metabolic process;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0008354//germ cell migration;GO:0002371//dendritic cell cytokine production;GO:0038109//Kit signaling pathway;GO:0046777//protein autophosphorylation;GO:0032762//mast cell cytokine production;GO:0038162//erythropoietin-mediated signaling pathway;GO:0000187//activation of MAPK activity;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0030335//positive regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030218//erythrocyte differentiation;GO:0030217//T cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0097324//melanocyte migration;GO:0035162//embryonic hemopoiesis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030032//lamellipodium assembly;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0008584//male gonad development;GO:0048103//somatic stem cell division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008542//visual learning;GO:0010863//positive regulation of phospholipase C activity;GO:0035019//somatic stem cell maintenance;GO:0030318//melanocyte differentiation;GO:0002551//mast cell chemotaxis;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0043069//negative regulation of programmed cell death;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0038093//Fc receptor signaling pathway;GO:0048565//digestive tract development;GO:0043303//mast cell degranulation;GO:0045747//positive regulation of Notch signaling pathway;GO:0070662//mast cell proliferation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0097326//melanocyte adhesion;GO:0007286//spermatid development;GO:0046427//positive regulation of JAK-STAT cascade;GO:0031532//actin cytoskeleton reorganization;GO:0002320//lymphoid progenitor cell differentiation;GO:0035855//megakaryocyte development;GO:0043473//pigmentation;GO:0030097//hemopoiesis;GO:0048863//stem cell differentiation;GO:0048070//regulation of developmental pigmentation;GO:0035234//ectopic germ cell programmed cell death;GO:0019827//stem cell maintenance;GO:0007283//spermatogenesis;GO:0060374//mast cell differentiation;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0042127//regulation of cell proliferation;GO:0097067//cellular response to thyroid hormone stimulus;GO:0002318//myeloid progenitor cell differentiation;GO:0023014//signal transduction by phosphorylation;GO:0010628//positive regulation of gene expression;GO:0008360//regulation of cell shape;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008284//positive regulation of cell proliferation;GO:0060326//cell chemotaxis;GO:0050673//epithelial cell proliferation,GO:0019955//cytokine binding;GO:0005020//stem cell factor receptor activity;GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0002020//protease binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0042803//protein homodimerization activity,K05091//Pathways in cancer;Acute myeloid leukemia;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Endocytosis;Melanogenesis
3816,0,0,0,0,4,0,0,0,11,0,0,0,KLK1;kallikrein 1,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01325//Endocrine and other factor-regulated calcium reabsorption
3817,0,333,7,297,846,18,0,2,18,0,0,0,KLK2;kallikrein-related peptidase 2,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization,GO:0004252//serine-type endopeptidase activity,K01351//Pathways in cancer;Prostate cancer;K01325//Endocrine and other factor-regulated calcium reabsorption
3818,52,0,0,0,0,0,0,0,9,0,0,0,"KLKB1;kallikrein B, plasma (Fletcher factor) 1",GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,"GO:0006508//proteolysis;GO:0051919//positive regulation of fibrinolysis;GO:0031638//zymogen activation;GO:0042730//fibrinolysis;GO:0007596//blood coagulation;GO:0031639//plasminogen activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0002542//Factor XII activation;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly",GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K01324//Complement and coagulation cascades
382,0,52,27,42,55,0,3,82,0,1,48,0,ARF6;ADP-ribosylation factor 6,GO:0031527//filopodium membrane;GO:0001726//ruffle;GO:0032154//cleavage furrow;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005938//cell cortex;GO:0030139//endocytic vesicle;GO:0030496//midbody;GO:0005925//focal adhesion;GO:0055038//recycling endosome membrane,GO:0030838//positive regulation of actin filament polymerization;GO:0036010//protein localization to endosome;GO:0030866//cortical actin cytoskeleton organization;GO:0006928//cellular component movement;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0007155//cell adhesion;GO:0051489//regulation of filopodium assembly;GO:0051301//cell division;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0033028//myeloid cell apoptotic process;GO:0060998//regulation of dendritic spine development;GO:0031529//ruffle organization;GO:0001889//liver development;GO:0035020//regulation of Rac protein signal transduction;GO:0007049//cell cycle;GO:0034394//protein localization to cell surface;GO:0097284//hepatocyte apoptotic process;GO:0006184//GTP catabolic process;GO:0090162//establishment of epithelial cell polarity;GO:0015031//protein transport,GO:0031996//thioesterase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,K07941//Endocytosis;Fc gamma R-mediated phagocytosis
3820,0,0,0,12,0,0,0,0,25,0,0,0,"KLRB1;killer cell lectin-like receptor subfamily B, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007166//cell surface receptor signaling pathway,GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity,K06543//Natural killer cell mediated cytotoxicity;Malaria
3821,0,0,0,0,0,0,0,0,17,0,0,0,"KLRC1;killer cell lectin-like receptor subfamily C, member 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0050776//regulation of immune response,GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity,K06541//Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Antigen processing and presentation
3822,0,0,0,0,0,0,0,0,31,0,14,0,"KLRC2;killer cell lectin-like receptor subfamily C, member 2",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0006968//cellular defense response,GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K06541//Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Antigen processing and presentation
3824,0,0,0,0,0,26,0,0,15,0,0,0,"KLRD1;killer cell lectin-like receptor subfamily D, member 1",GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0050776//regulation of immune response;GO:0007166//cell surface receptor signaling pathway;GO:0045087//innate immune response,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding,K06516//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease
3827,1,0,0,0,0,0,43,0,32,0,0,0,KNG1;kininogen 1,GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0072562//blood microparticle,"GO:0030195//negative regulation of blood coagulation;GO:0043065//positive regulation of apoptotic process;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0035815//positive regulation of renal sodium excretion;GO:0042311//vasodilation;GO:0010951//negative regulation of endopeptidase activity;GO:0007162//negative regulation of cell adhesion;GO:0030168//platelet activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0035810//positive regulation of urine volume;GO:0045861//negative regulation of proteolysis;GO:0006954//inflammatory response;GO:0006939//smooth muscle contraction;GO:0007204//positive regulation of cytosolic calcium ion concentration",GO:0005102//receptor binding;GO:0008270//zinc ion binding;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity,K03898//Complement and coagulation cascades
383,89,0,0,0,1,0,0,5,15,0,0,0,ARG1;arginase 1,GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0000050//urea cycle;GO:0071377//cellular response to glucagon stimulus;GO:0042493//response to drug;GO:0014075//response to amine;GO:0044281//small molecule metabolic process;GO:0001889//liver development;GO:0060056//mammary gland involution;GO:0010269//response to selenium ion;GO:0046686//response to cadmium ion;GO:0070301//cellular response to hydrogen peroxide;GO:0033197//response to vitamin E;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0001938//positive regulation of endothelial cell proliferation;GO:0010042//response to manganese ion;GO:0071353//cellular response to interleukin-4;GO:0010043//response to zinc ion;GO:0006527//arginine catabolic process;GO:0051597//response to methylmercury;GO:0032964//collagen biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0010963//regulation of L-arginine import;GO:0033189//response to vitamin A;GO:0030324//lung development;GO:0071549//cellular response to dexamethasone stimulus;GO:0009635//response to herbicide;GO:0060135//maternal process involved in female pregnancy;GO:0043200//response to amino acid;GO:0070207//protein homotrimerization;GO:0048678//response to axon injury;GO:0034641//cellular nitrogen compound metabolic process,GO:0030145//manganese ion binding;GO:0004053//arginase activity,K01476//Amoebiasis;Glutathione metabolism;Arginine and proline metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
3831,0,1,0,0,21,26,12,0,7,0,32,0,KLC1;kinesin light chain 1,GO:0030426//growth cone;GO:0005874//microtubule;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005871//kinesin complex;GO:0005829//cytosol;GO:0016020//membrane,GO:0016032//viral process;GO:0035617//stress granule disassembly;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0008152//metabolic process,GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0003774//motor activity,K10407//Salmonella infection
3832,0,0,0,0,15,44,0,0,52,301,10,1,KIF11;kinesin family member 11,GO:0005819//spindle;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0000922//spindle pole;GO:0005876//spindle microtubule;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005871//kinesin complex,GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007100//mitotic centrosome separation;GO:0007051//spindle organization;GO:0090307//spindle assembly involved in mitosis;GO:0007059//chromosome segregation;GO:0007052//mitotic spindle organization;GO:0008152//metabolic process;GO:0007018//microtubule-based movement;GO:0007067//mitotic nuclear division;GO:0006200//ATP catabolic process,GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0019901//protein kinase binding;GO:0016887//ATPase activity,-
3833,0,0,0,0,0,0,11,1,12,0,0,0,KIFC1;kinesin family member C1,GO:0005874//microtubule;GO:0005819//spindle;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005871//kinesin complex;GO:0016020//membrane;GO:0005769//early endosome,GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0007596//blood coagulation;GO:0007018//microtubule-based movement;GO:0000070//mitotic sister chromatid segregation;GO:0051225//spindle assembly,GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0005524//ATP binding,-
3834,0,0,0,0,0,22,0,0,0,0,7,0,KIF25;kinesin family member 25,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005871//kinesin complex,GO:0010507//negative regulation of autophagy;GO:0008152//metabolic process;GO:0006200//ATP catabolic process;GO:0006996//organelle organization;GO:0007018//microtubule-based movement;GO:0000070//mitotic sister chromatid segregation,GO:0005524//ATP binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity,-
3835,72,42,25,10,8,0,29,0,7,0,3,0,KIF22;kinesin family member 22,GO:0005634//nucleus;GO:0005874//microtubule;GO:0000785//chromatin;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0000776//kinetochore,GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0007596//blood coagulation,GO:0016887//ATPase activity;GO:0003677//DNA binding;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0005524//ATP binding,-
3836,0,52,1,81,237,30,0,0,59,0,28,0,KPNA1;karyopherin alpha 1 (importin alpha 5),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0030425//dendrite;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0000018//regulation of DNA recombination;GO:0075733//intracellular transport of virus;GO:0006309//apoptotic DNA fragmentation;GO:0019221//cytokine-mediated signaling pathway;GO:0006915//apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006607//NLS-bearing protein import into nucleus;GO:0019058//viral life cycle;GO:0016032//viral process;GO:0042307//positive regulation of protein import into nucleus,GO:0005515//protein binding;GO:0008139//nuclear localization sequence binding;GO:0008565//protein transporter activity,K15042//Influenza A
3837,72,69,2,68,240,0,37,0,72,0,12,0,KPNB1;karyopherin (importin) beta 1,GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0071782//endoplasmic reticulum tubular network;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0044281//small molecule metabolic process;GO:0019058//viral life cycle;GO:0006607//NLS-bearing protein import into nucleus;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006610//ribosomal protein import into nucleus;GO:0000060//protein import into nucleus, translocation;GO:0006606//protein import into nucleus;GO:0016032//viral process;GO:0019221//cytokine-mediated signaling pathway;GO:0006309//apoptotic DNA fragmentation;GO:0075733//intracellular transport of virus;GO:0006915//apoptotic process",GO:0008139//nuclear localization sequence binding;GO:0008536//Ran GTPase binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008565//protein transporter activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding,K14293//RNA transport
3838,0,0,0,0,0,14,0,0,28,0,0,0,"KPNA2;karyopherin alpha 2 (RAG cohort 1, importin alpha 1)",GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000018//regulation of DNA recombination;GO:0006607//NLS-bearing protein import into nucleus;GO:0006259//DNA metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0016032//viral process,GO:0008139//nuclear localization sequence binding;GO:0008565//protein transporter activity;GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K15043//Influenza A
3839,0,0,0,15,17,44,28,0,59,0,4,1,KPNA3;karyopherin alpha 3 (importin alpha 4),GO:0005643//nuclear pore;GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0019221//cytokine-mediated signaling pathway;GO:0006607//NLS-bearing protein import into nucleus;GO:0046718//viral entry into host cell;GO:0006461//protein complex assembly;GO:0075732//viral penetration into host nucleus,GO:0008139//nuclear localization sequence binding;GO:0008022//protein C-terminus binding;GO:0008565//protein transporter activity;GO:0005515//protein binding,K15043//Influenza A
384,0,676,369,1020,1200,29,9,0,74,214,708,0,ARG2;arginase 2,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006809//nitric oxide biosynthetic process;GO:0006941//striated muscle contraction;GO:0006525//arginine metabolic process;GO:0000050//urea cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0001657//ureteric bud development;GO:0044281//small molecule metabolic process,GO:0004053//arginase activity;GO:0046872//metal ion binding,K01476//Metabolic pathways;Amoebiasis;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Glutathione metabolism
3840,0,30,67,27,129,18,26,63,28,0,32,0,KPNA4;karyopherin alpha 4 (importin alpha 3),GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm,GO:0019221//cytokine-mediated signaling pathway;GO:0006607//NLS-bearing protein import into nucleus,GO:0005515//protein binding;GO:0008565//protein transporter activity,K15043//Influenza A
3841,0,0,0,4,16,0,0,0,19,0,0,0,KPNA5;karyopherin alpha 5 (importin alpha 6),GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0019221//cytokine-mediated signaling pathway;GO:0006607//NLS-bearing protein import into nucleus,GO:0005515//protein binding;GO:0008565//protein transporter activity,K15042//Influenza A
3842,0,38,1,26,133,31,3,0,112,0,0,0,TNPO1;transportin 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000060//protein import into nucleus, translocation;GO:0016032//viral process;GO:0010467//gene expression;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0008536//Ran GTPase binding;GO:0008139//nuclear localization sequence binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14293//RNA transport
3843,25,57,2,16,198,20,4,0,38,0,1,0,IPO5;importin 5,GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane,GO:0016032//viral process;GO:0043086//negative regulation of catalytic activity;GO:0042307//positive regulation of protein import into nucleus;GO:0071230//cellular response to amino acid stimulus;GO:0006607//NLS-bearing protein import into nucleus;GO:0006610//ribosomal protein import into nucleus,GO:0005095//GTPase inhibitor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008565//protein transporter activity;GO:0008536//Ran GTPase binding,K14293//RNA transport
3845,0,3,26,147,273,0,0,0,23,1,35,0,KRAS;Kirsten rat sarcoma viral oncogene homolog,GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0005739//mitochondrion;GO:0016020//membrane,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0051384//response to glucocorticoid;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0030036//actin cytoskeleton organization;GO:0000165//MAPK cascade;GO:0006184//GTP catabolic process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035022//positive regulation of Rac protein signal transduction;GO:0007411//axon guidance;GO:0050900//leukocyte migration;GO:0045596//negative regulation of cell differentiation;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0019221//cytokine-mediated signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0045087//innate immune response;GO:0007265//Ras protein signal transduction;GO:0000186//activation of MAPKK activity;GO:0010628//positive regulation of gene expression;GO:0051385//response to mineralocorticoid;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008542//visual learning;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0007596//blood coagulation;GO:0035176//social behavior;GO:0051146//striated muscle cell differentiation;GO:0008286//insulin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation",GO:0019003//GDP binding;GO:0005515//protein binding;GO:0019002//GMP binding;GO:0030275//LRR domain binding;GO:0005525//GTP binding;GO:0032403//protein complex binding,K07827//HTLV-I infection;Long-term depression;Endometrial cancer;MAPK signaling pathway - fly;VEGF signaling pathway;Thyroid cancer;Glioma;Pancreatic cancer;Gap junction;Pathways in cancer;GnRH signaling pathway;Chemokine signaling pathway;Alcoholism;Serotonergic synapse;MAPK signaling pathway;Renal cell carcinoma;ErbB signaling pathway;Bladder cancer;Fc epsilon RI signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Tight junction;B cell receptor signaling pathway;Neurotrophin signaling pathway;Melanoma;Hepatitis C;Regulation of actin cytoskeleton;Non-small cell lung cancer;Dorso-ventral axis formation;Melanogenesis;Insulin signaling pathway;Axon guidance;Long-term potentiation;Progesterone-mediated oocyte maturation;Prostate cancer;Aldosterone-regulated sodium reabsorption;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Colorectal cancer
3846,121,0,0,0,0,0,0,0,0,0,0,0,KRTAP5-9;keratin associated protein 5-9,GO:0045095//keratin filament,GO:0008544//epidermis development,GO:0005515//protein binding,-
3848,99,0,0,0,0,0,0,0,35,0,0,0,KRT1;keratin 1,GO:0072562//blood microparticle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0045095//keratin filament,"GO:0045765//regulation of angiogenesis;GO:0042730//fibrinolysis;GO:0001895//retina homeostasis;GO:0061436//establishment of skin barrier;GO:0006979//response to oxidative stress;GO:0001867//complement activation, lectin pathway;GO:0050728//negative regulation of inflammatory response",GO:0005515//protein binding;GO:0030246//carbohydrate binding;GO:0005198//structural molecule activity;GO:0004872//receptor activity,-
3849,2,0,0,0,0,8,0,36,14,0,10,0,KRT2;keratin 2,GO:0005634//nucleus;GO:0045095//keratin filament;GO:0045111//intermediate filament cytoskeleton;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0016020//membrane,GO:0032980//keratinocyte activation;GO:0008544//epidermis development;GO:0043616//keratinocyte proliferation;GO:0051546//keratinocyte migration;GO:0031424//keratinization,GO:0005200//structural constituent of cytoskeleton,-
3850,0,0,0,0,0,5,0,2,51,0,23,0,KRT3;keratin 3,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament,GO:0030855//epithelial cell differentiation;GO:0045104//intermediate filament cytoskeleton organization,GO:0005198//structural molecule activity,-
3851,0,0,0,0,0,0,0,42,22,0,0,0,KRT4;keratin 4,GO:0045095//keratin filament;GO:0005634//nucleus;GO:0009986//cell surface;GO:0005882//intermediate filament;GO:0045111//intermediate filament cytoskeleton,GO:0050680//negative regulation of epithelial cell proliferation;GO:0007010//cytoskeleton organization;GO:0030855//epithelial cell differentiation,GO:0005198//structural molecule activity;GO:0005515//protein binding,-
3852,76,0,36,0,0,1,0,0,12,0,0,0,KRT5;keratin 5,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0045095//keratin filament;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0008544//epidermis development;GO:0031581//hemidesmosome assembly;GO:0034329//cell junction assembly,GO:0097110//scaffold protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,-
3853,0,0,0,0,0,0,17,0,14,9,1,0,KRT6A;keratin 6A,GO:0005634//nucleus;GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0008284//positive regulation of cell proliferation;GO:0030154//cell differentiation,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton,-
3854,0,0,0,0,22,14,30,0,3,162,0,0,KRT6B;keratin 6B,GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,GO:0007398//ectoderm development,GO:0005200//structural constituent of cytoskeleton,-
3855,63,1,0,0,0,0,0,0,14,0,5,0,KRT7;keratin 7,GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045095//keratin filament,GO:0016032//viral process,GO:0005515//protein binding;GO:0005198//structural molecule activity,-
3856,13,5103,3554,5885,7760,0,369,3467,702,873,11764,621,KRT8;keratin 8,GO:0042383//sarcolemma;GO:0016363//nuclear matrix;GO:0045095//keratin filament;GO:0005634//nucleus;GO:0043034//costamere;GO:0016010//dystrophin-associated glycoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0030018//Z disc;GO:0005654//nucleoplasm;GO:0005911//cell-cell junction;GO:0005737//cytoplasm,GO:0060706//cell differentiation involved in embryonic placenta development;GO:0097191//extrinsic apoptotic signaling pathway;GO:0051599//response to hydrostatic pressure;GO:0097284//hepatocyte apoptotic process;GO:0045214//sarcomere organization;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0051707//response to other organism;GO:0016032//viral process,GO:0097110//scaffold protein binding;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0005198//structural molecule activity,-
3858,0,58,0,71,150,0,1,0,7,0,10,0,KRT10;keratin 10,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045095//keratin filament,GO:0071277//cellular response to calcium ion;GO:0030216//keratinocyte differentiation,GO:0030280//structural constituent of epidermis,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
3859,0,0,0,0,0,0,15,0,19,0,0,0,KRT12;keratin 12,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0007601//visual perception,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
3860,0,0,0,0,0,0,0,0,1,0,0,0,KRT13;keratin 13,GO:0005634//nucleus;GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome;GO:0045111//intermediate filament cytoskeleton,GO:0009314//response to radiation;GO:0071300//cellular response to retinoic acid;GO:0043587//tongue morphogenesis;GO:0007010//cytoskeleton organization,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
3861,0,0,0,0,0,39,0,1,0,0,0,0,KRT14;keratin 14,GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament;GO:0071944//cell periphery;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010212//response to ionizing radiation;GO:0045110//intermediate filament bundle assembly;GO:0007568//aging;GO:0010043//response to zinc ion;GO:0031581//hemidesmosome assembly;GO:0030855//epithelial cell differentiation;GO:0034329//cell junction assembly;GO:0042633//hair cycle;GO:0008544//epidermis development,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:1990254//keratin filament binding,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
3866,0,0,0,0,0,0,0,56,34,0,0,0,KRT15;keratin 15,GO:0005634//nucleus;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0008544//epidermis development,GO:0005200//structural constituent of cytoskeleton;GO:0097110//scaffold protein binding;GO:0005515//protein binding,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
386617,16,0,0,0,0,0,4,0,32,0,0,0,KCTD8;potassium channel tetramerization domain containing 8,GO:0043235//receptor complex;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0045211//postsynaptic membrane,GO:0051260//protein homooligomerization;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,-,-
386618,0,0,0,0,0,0,0,0,37,0,18,0,KCTD4;potassium channel tetramerization domain containing 4,-,GO:0051260//protein homooligomerization,-,-
386653,91,0,0,0,0,0,0,0,0,0,0,0,IL31;interleukin 31,GO:0005615//extracellular space,GO:0002376//immune system process,GO:0005125//cytokine activity,-
386675,1,0,0,0,0,0,0,0,0,0,0,0,KRTAP10-7;keratin associated protein 10-7,GO:0045095//keratin filament,-,-,-
386676,0,0,0,0,0,0,0,0,13,0,0,0,KRTAP10-9;keratin associated protein 10-9,GO:0045095//keratin filament,-,-,-
386679,0,0,0,0,0,0,0,0,18,0,0,0,KRTAP10-2;keratin associated protein 10-2,GO:0045095//keratin filament,-,-,-
386682,0,0,0,0,0,0,0,0,23,0,0,0,KRTAP10-3;keratin associated protein 10-3,GO:0045095//keratin filament,-,-,-
386683,0,0,0,0,0,22,0,0,0,0,0,0,KRTAP12-3;keratin associated protein 12-3,GO:0045095//keratin filament,-,-,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
386685,0,0,0,0,0,0,0,0,0,0,5,0,KRTAP10-12;keratin associated protein 10-12,GO:0045095//keratin filament,-,-,-
386724,62,0,0,2,0,0,12,48,0,0,1,0,AMIGO3;adhesion molecule with Ig-like domain 3,GO:0016021//integral component of membrane,GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,-,K06850//Axon guidance
386746,0,0,0,0,0,0,0,0,22,0,0,0,"MRGPRG;MAS-related GPR, member G",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
386757,1,0,0,0,2,38,13,28,67,11,30,0,"SLC6A10P;solute carrier family 6 (neurotransmitter transporter), member 10, pseudogene",-,-,-,K05039//GABAergic synapse
3868,42,0,0,0,0,0,0,3,0,0,0,0,KRT16;keratin 16,GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:0030336//negative regulation of cell migration;GO:0045104//intermediate filament cytoskeleton organization;GO:0042633//hair cycle;GO:0007010//cytoskeleton organization;GO:0007568//aging;GO:0008283//cell proliferation;GO:0008544//epidermis development,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
387,0,98,2,47,314,9,3,5,20,0,15,0,RHOA;ras homolog family member A,GO:0032154//cleavage furrow;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0030027//lamellipodium;GO:0005938//cell cortex;GO:0005856//cytoskeleton;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0030424//axon;GO:0030496//midbody;GO:0005925//focal adhesion;GO:0043296//apical junction complex;GO:0005634//nucleus,GO:0048015//phosphatidylinositol-mediated signaling;GO:0050770//regulation of axonogenesis;GO:0043525//positive regulation of neuron apoptotic process;GO:0030307//positive regulation of cell growth;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043931//ossification involved in bone maturation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0009749//response to glucose;GO:0007264//small GTPase mediated signal transduction;GO:0045907//positive regulation of vasoconstriction;GO:0051924//regulation of calcium ion transport;GO:0043149//stress fiber assembly;GO:0050919//negative chemotaxis;GO:0007519//skeletal muscle tissue development;GO:0007596//blood coagulation;GO:0071803//positive regulation of podosome assembly;GO:0030168//platelet activation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0038027//apolipoprotein A-I-mediated signaling pathway;GO:0030334//regulation of cell migration;GO:0045666//positive regulation of neuron differentiation;GO:0033688//regulation of osteoblast proliferation;GO:0043524//negative regulation of neuron apoptotic process;GO:0016032//viral process;GO:0021861//forebrain radial glial cell differentiation;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0050771//negative regulation of axonogenesis;GO:0030335//positive regulation of cell migration;GO:0045471//response to ethanol;GO:0007411//axon guidance;GO:0045665//negative regulation of neuron differentiation;GO:0006184//GTP catabolic process;GO:0030036//actin cytoskeleton organization;GO:0051384//response to glucocorticoid;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042493//response to drug;GO:0051056//regulation of small GTPase mediated signal transduction;GO:2000177//regulation of neural precursor cell proliferation;GO:0045987//positive regulation of smooth muscle contraction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0061383//trabecula morphogenesis;GO:0090307//spindle assembly involved in mitosis;GO:0031098//stress-activated protein kinase signaling cascade;GO:0036089//cleavage furrow formation;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0043297//apical junction assembly;GO:0043200//response to amino acid;GO:0009612//response to mechanical stimulus;GO:0001666//response to hypoxia;GO:0007160//cell-matrix adhesion;GO:0021795//cerebral cortex cell migration;GO:0007266//Rho protein signal transduction;GO:0021762//substantia nigra development;GO:0045785//positive regulation of cell adhesion;GO:0050772//positive regulation of axonogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0050773//regulation of dendrite development;GO:0032467//positive regulation of cytokinesis;GO:0045727//positive regulation of translation;GO:0030521//androgen receptor signaling pathway;GO:0030838//positive regulation of actin filament polymerization,GO:0003924//GTPase activity;GO:0019904//protein domain specific binding;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0005515//protein binding;GO:0017022//myosin binding,K04513//TGF-beta signaling pathway;Leukocyte transendothelial migration;Bacterial invasion of epithelial cells;Tight junction;Focal adhesion;Pathogenic Escherichia coli infection;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Pancreatic secretion;Tuberculosis;Pertussis;Endocytosis;Axon guidance;Chemokine signaling pathway;Pathways in cancer;Colorectal cancer;Adherens junction;Vascular smooth muscle contraction;Wnt signaling pathway;T cell receptor signaling pathway
387032,0,0,0,0,0,0,0,1,12,0,6,0,ZKSCAN4;zinc finger with KRAB and SCAN domains 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
387036,0,0,0,0,0,0,0,0,14,0,0,0,"GUSBP2;glucuronidase, beta pseudogene 2",-,-,-,K01195//Porphyrin and chlorophyll metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Glycosaminoglycan degradation;Starch and sucrose metabolism;Drug metabolism - other enzymes;Lysosome
387065,0,0,0,0,0,0,42,0,0,0,0,0,HMGA1P7;high mobility group AT-hook 1 pseudogene 7,-,-,-,-
387066,0,0,0,0,37,0,0,0,33,0,0,0,SNHG5;small nucleolar RNA host gene 5 (non-protein coding),-,-,-,-
387103,81,0,0,0,0,0,0,0,30,0,0,0,CENPW;centromere protein W,"GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0000775//chromosome, centromeric region",GO:0051276//chromosome organization;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0051382//kinetochore assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0007059//chromosome segregation,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,-
387104,0,0,0,22,1,0,0,0,10,0,25,0,SOGA3;SOGA family member 3,GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0010506//regulation of autophagy,-,K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
387119,196,0,1,15,0,0,27,0,30,0,0,0,CEP85L;centrosomal protein 85kDa-like,GO:0005813//centrosome;GO:0005737//cytoplasm,-,-,K12478//Tuberculosis;Endocytosis;Phagosome;K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
3872,0,0,0,0,0,9,26,0,9,0,1,0,KRT17;keratin 17,GO:0071944//cell periphery;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0007165//signal transduction;GO:0051798//positive regulation of hair follicle development;GO:0045727//positive regulation of translation;GO:0045109//intermediate filament organization;GO:0031424//keratinization;GO:0030307//positive regulation of cell growth;GO:0002009//morphogenesis of an epithelium;GO:0008544//epidermis development,GO:0005200//structural constituent of cytoskeleton;GO:0032395//MHC class II receptor activity;GO:0042289//MHC class II protein binding;GO:0005515//protein binding,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
387254,0,0,0,0,0,14,0,0,19,0,0,0,"SLC7A5P2;solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2",GO:0016021//integral component of membrane,GO:0003333//amino acid transmembrane transport,GO:0015171//amino acid transmembrane transporter activity,-
387263,0,263,244,454,533,0,19,8,9,119,466,0,C6orf120;chromosome 6 open reading frame 120,GO:0070062//extracellular vesicular exosome,GO:0006915//apoptotic process,-,K10848//Nucleotide excision repair;Fanconi anemia pathway
387266,4,0,0,0,0,0,0,0,0,0,8,0,KRTAP5-3;keratin associated protein 5-3,GO:0045095//keratin filament,-,-,-
387273,0,0,0,0,0,7,0,0,0,0,0,0,KRTAP5-10;keratin associated protein 5-10,GO:0045095//keratin filament,-,-,-
387316,41,46,0,0,0,0,0,0,2,0,0,0,VN1R10P;vomeronasal 1 receptor 10 pseudogene,-,-,-,-
387332,100,0,0,0,0,15,0,0,11,0,0,0,TBPL2;TATA box binding protein like 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006352//DNA-templated transcription, initiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K03120//Epstein-Barr virus infection;Basal transcription factors;Herpes simplex infection;HTLV-I infection;Huntington's disease
387338,0,30,2,6,52,11,33,0,26,0,8,0,"NSUN4;NOP2/Sun domain family, member 4",GO:0005762//mitochondrial large ribosomal subunit,GO:0031167//rRNA methylation,GO:0003723//RNA binding;GO:0008168//methyltransferase activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
387357,1,0,0,0,0,0,0,0,34,0,0,0,THEMIS;thymocyte selection associated,GO:0008180//COP9 signalosome;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005634//nucleus,GO:0043383//negative T cell selection;GO:0043368//positive T cell selection;GO:0050852//T cell receptor signaling pathway,GO:0005515//protein binding,-
387496,0,0,0,0,0,0,0,0,3,0,0,0,"RASL11A;RAS-like, family 11, member A",GO:0016020//membrane;GO:0005730//nucleolus,"GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0006351//transcription, DNA-templated",GO:0005525//GTP binding,-
3875,0,699,183,257,689,0,55,232,150,2,897,1,KRT18;keratin 18,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0045095//keratin filament;GO:0005815//microtubule organizing center;GO:0071944//cell periphery;GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus;GO:0034451//centriolar satellite,GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007049//cell cycle;GO:0045104//intermediate filament cytoskeleton organization;GO:0016032//viral process;GO:0043000//Golgi to plasma membrane CFTR protein transport;GO:0043066//negative regulation of apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097284//hepatocyte apoptotic process;GO:0009653//anatomical structure morphogenesis,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005198//structural molecule activity;GO:0097110//scaffold protein binding,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
387509,20,0,0,0,0,22,0,0,55,0,0,0,GPR153;G protein-coupled receptor 153,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
387521,1,0,0,0,0,0,0,0,9,50,0,0,TMEM189;transmembrane protein 189,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
387590,0,0,0,0,14,0,0,36,0,0,0,0,TPTEP1;transmembrane phosphatase with tensin homology pseudogene 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
387597,0,0,0,0,0,0,53,0,36,0,0,0,ILDR2;immunoglobulin-like domain containing receptor 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030154//cell differentiation;GO:0009749//response to glucose;GO:0030073//insulin secretion;GO:0031016//pancreas development;GO:0048873//homeostasis of number of cells within a tissue,-,-
387601,0,0,0,0,0,1,0,0,8,0,0,0,"SLC22A25;solute carrier family 22, member 25",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
387628,0,0,13,11,11,16,0,74,56,0,0,0,KGFLP1;fibroblast growth factor 7 pseudogene,-,-,-,K04358//Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Melanoma
387640,0,0,0,6,9,2,0,0,11,0,0,0,SKIDA1;SKI/DACH domain containing 1,GO:0005634//nucleus,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
387644,0,0,0,0,0,30,0,1,72,0,0,0,LINC00202-1;long intergenic non-protein coding RNA 202-1,-,-,-,-
387646,65,0,0,0,0,11,2,0,27,0,0,0,"LRRC37A6P;leucine rich repeat containing 37, member A6, pseudogene",-,-,-,K06838//Axon guidance;K06839//Axon guidance
387680,0,0,1,22,41,21,0,150,7,1,66,0,"FAM21A;family with sequence similarity 21, member A",GO:0071203//WASH complex;GO:0005769//early endosome;GO:0031901//early endosome membrane,"GO:0042147//retrograde transport, endosome to Golgi",-,-
387694,90,0,0,0,0,0,0,0,9,183,15,0,SH2D4B;SH2 domain containing 4B,-,-,-,-
387695,0,0,0,0,0,0,24,0,0,0,0,0,C10orf99;chromosome 10 open reading frame 99,GO:0005576//extracellular region,-,-,-
387700,0,0,0,0,0,0,0,0,41,0,0,0,"SLC16A12;solute carrier family 16, member 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
387707,0,0,0,0,16,36,0,0,0,0,0,0,CC2D2B;coiled-coil and C2 domain containing 2B,-,-,-,K02889//Ribosome
387712,0,45,0,23,15,7,0,0,14,2,20,2,ENO4;enolase family member 4,GO:0000015//phosphopyruvate hydratase complex,GO:0006096//glycolytic process,GO:0000287//magnesium ion binding;GO:0004634//phosphopyruvate hydratase activity,K01689//Microbial metabolism in diverse environments;Metabolic pathways;RNA degradation;Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis
387715,0,0,0,0,0,0,0,45,16,0,12,0,ARMS2;age-related maculopathy susceptibility 2,GO:0001917//photoreceptor inner segment;GO:0005739//mitochondrion,GO:0001895//retina homeostasis,-,-
387718,0,0,0,0,0,0,0,0,12,0,0,0,TEX36;testis expressed 36,-,-,-,-
387733,0,1,0,0,0,0,0,0,1,0,0,10,IFITM5;interferon induced transmembrane protein 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0030282//bone mineralization;GO:0030500//regulation of bone mineralization;GO:0009607//response to biotic stimulus,-,K06566//B cell receptor signaling pathway
387748,0,0,0,0,0,0,0,0,0,0,0,289,"OR56B1;olfactory receptor, family 56, subfamily B, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
387751,129,0,0,0,0,38,0,0,28,0,0,0,"GVINP1;GTPase, very large interferon inducible pseudogene 1",GO:0005829//cytosol;GO:0005634//nucleus,-,GO:0005525//GTP binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K12797//NOD-like receptor signaling pathway
387755,0,0,0,0,0,13,0,0,33,0,2,0,INSC;inscuteable homolog (Drosophila),GO:0005737//cytoplasm;GO:0045177//apical part of cell,GO:0000132//establishment of mitotic spindle orientation;GO:0060487//lung epithelial cell differentiation;GO:0007399//nervous system development,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
387758,0,0,0,0,0,0,0,0,42,0,0,0,FIBIN;fin bud initiation factor homolog (zebrafish),GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,-,-,-
387775,0,0,0,0,0,0,0,0,15,0,0,0,"SLC22A10;solute carrier family 22, member 10",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,-
387778,0,0,0,0,0,0,0,61,10,0,1,0,SPDYC;speedy/RINGO cell cycle regulator family member C,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007049//cell cycle,GO:0019901//protein kinase binding,K08694//Oocyte meiosis;Progesterone-mediated oocyte maturation
387787,0,21,15,5,52,0,0,3,0,0,35,0,LIPT2;lipoyl(octanoyl) transferase 2 (putative),GO:0005739//mitochondrion,GO:0009107//lipoate biosynthetic process;GO:0006464//cellular protein modification process,GO:0016415//octanoyltransferase activity;GO:0033819//lipoyl(octanoyl) transferase activity;GO:0016874//ligase activity,K03801//Lipoic acid metabolism;Metabolic pathways
387804,0,0,0,0,0,0,0,56,0,0,0,0,VSTM5;V-set and transmembrane domain containing 5,GO:0016021//integral component of membrane,-,-,-
387836,0,0,0,0,0,12,0,0,29,1,0,0,"CLEC2A;C-type lectin domain family 2, member A",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042267//natural killer cell mediated cytotoxicity,GO:0042803//protein homodimerization activity;GO:0030246//carbohydrate binding;GO:0005515//protein binding,-
387837,0,0,0,0,0,15,0,0,26,0,0,0,"CLEC12B;C-type lectin domain family 12, member B",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,GO:0030246//carbohydrate binding,-
387841,0,0,0,0,0,0,0,0,0,0,5,0,RPL13AP20;ribosomal protein L13a pseudogene 20,-,-,-,K02872//Ribosome
387849,0,41,4,0,0,0,0,0,6,0,0,0,REP15;RAB15 effector protein,GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome;GO:0010008//endosome membrane;GO:0031901//early endosome membrane,GO:0033572//transferrin transport;GO:0001881//receptor recycling,GO:0005515//protein binding,-
387856,0,0,0,0,0,14,0,0,4,0,0,0,CCDC184;coiled-coil domain containing 184,GO:0005737//cytoplasm,-,-,-
387882,0,0,0,0,0,0,0,0,17,0,0,0,C12orf75;chromosome 12 open reading frame 75,-,-,-,-
387885,0,78,0,78,71,13,17,115,87,0,161,1,CCDC42B;coiled-coil domain containing 42B,-,-,-,-
387890,0,0,0,0,0,0,0,0,22,0,0,0,TMEM233;transmembrane protein 233,GO:0016021//integral component of membrane,GO:0009607//response to biotic stimulus,-,-
387893,0,0,0,1,78,33,0,0,16,53,10,0,SETD8;SET domain containing (lysine methyltransferase) 8,GO:0005730//nucleolus;GO:0005694//chromosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0000278//mitotic cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007067//mitotic nuclear division;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0018026//peptidyl-lysine monomethylation;GO:0034968//histone lysine methylation",GO:0002039//p53 binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003714//transcription corepressor activity;GO:0016279//protein-lysine N-methyltransferase activity,K11428//Lysine degradation
387911,0,356,319,402,240,0,40,0,11,0,1408,0,C1QTNF9B;C1q and tumor necrosis factor related protein 9B,GO:0070062//extracellular vesicular exosome;GO:0005581//collagen trimer,-,-,K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus
387914,0,0,0,0,0,1,1,60,0,0,3,0,SHISA2;shisa family member 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007275//multicellular organismal development,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
387921,0,0,0,0,0,2,28,0,34,0,0,0,NHLRC3;NHL repeat containing 3,GO:0070062//extracellular vesicular exosome,-,-,-
387923,0,0,0,4,2,0,0,0,0,63,12,0,SERP2;stress-associated endoplasmic reticulum protein family member 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0015031//protein transport,-,-
387978,0,0,0,0,0,0,1,0,32,0,35,0,C14orf23;chromosome 14 open reading frame 23,-,-,-,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
387990,0,0,0,30,20,0,0,0,3,0,0,0,TOMM20L;translocase of outer mitochondrial membrane 20 homolog (yeast)-like,GO:0005742//mitochondrial outer membrane translocase complex;GO:0016021//integral component of membrane,GO:0006605//protein targeting,-,-
388,0,34,1,48,47,0,3,0,43,0,0,0,RHOB;ras homolog family member B,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0032154//cleavage furrow;GO:0010008//endosome membrane;GO:0031902//late endosome membrane;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005829//cytosol,GO:0006184//GTP catabolic process;GO:0070301//cellular response to hydrogen peroxide;GO:0015031//protein transport;GO:0007411//axon guidance;GO:0071479//cellular response to ionizing radiation;GO:0007264//small GTPase mediated signal transduction;GO:0045766//positive regulation of angiogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006927//transformed cell apoptotic process;GO:0001525//angiogenesis;GO:0008333//endosome to lysosome transport;GO:0006915//apoptotic process;GO:0007596//blood coagulation;GO:0043065//positive regulation of apoptotic process;GO:0007155//cell adhesion;GO:0045786//negative regulation of cell cycle;GO:0000910//cytokinesis;GO:0007266//Rho protein signal transduction;GO:0030168//platelet activation,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0005515//protein binding,-
3880,0,0,1,1,6,4,0,0,32,0,0,0,KRT19;keratin 19,GO:0043034//costamere;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0042383//sarcolemma;GO:0016010//dystrophin-associated glycoprotein complex;GO:0030018//Z disc;GO:0071944//cell periphery,GO:0016032//viral process;GO:0045214//sarcomere organization;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0043627//response to estrogen,GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0032403//protein complex binding;GO:0005200//structural constituent of cytoskeleton,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
388007,0,0,0,0,0,0,0,0,1,0,0,0,"SERPINA13P;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene",-,-,-,K03984//Complement and coagulation cascades
388015,0,0,0,0,0,0,0,0,14,0,0,0,RTL1;retrotransposon-like 1,GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development,-,K04389//Type I diabetes mellitus;Influenza A;African trypanosomiasis;Autoimmune thyroid disease;Chagas disease (American trypanosomiasis);Pathways in cancer;Measles;Allograft rejection;Cytokine-cytokine receptor interaction;Neurotrophin signaling pathway;MAPK signaling pathway;Herpes simplex infection;Natural killer cell mediated cytotoxicity;Graft-versus-host disease;Apoptosis;K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction;K04303//Renin-angiotensin system;Neuroactive ligand-receptor interaction;K02184//Dorso-ventral axis formation
388021,80,0,0,0,0,0,0,0,44,0,13,0,TMEM179;transmembrane protein 179,GO:0016021//integral component of membrane,-,-,K12323//Vascular smooth muscle contraction;Purine metabolism
3881,9,0,0,0,0,5,0,0,47,0,0,0,KRT31;keratin 31,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0008544//epidermis development,GO:0005200//structural constituent of cytoskeleton,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
388115,105,0,0,3,4,4,0,0,20,0,0,0,C15orf52;chromosome 15 open reading frame 52,-,-,GO:0044822//poly(A) RNA binding,-
388121,0,0,0,0,8,0,0,0,17,0,0,0,"TNFAIP8L3;tumor necrosis factor, alpha-induced protein 8-like 3",-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
388135,0,0,0,0,0,1,15,0,16,0,2,184,C15orf59;chromosome 15 open reading frame 59,-,-,-,-
388152,0,0,0,0,10,36,27,1,13,0,7,0,GOLGA2P7;golgin A2 pseudogene 7,-,-,-,K01528//Bacterial invasion of epithelial cells;Endocytosis;Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis
388165,0,38,0,0,4,0,0,43,11,0,9,0,UBE2Q2P1;ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 1,-,-,-,K10582//Ubiquitin mediated proteolysis
388182,0,0,20,0,0,0,0,88,0,0,0,1,SPATA41;spermatogenesis associated 41 (non-protein coding),-,-,-,-
388199,0,0,0,0,2,0,16,0,7,0,0,13,PRR25;proline rich 25,-,-,-,-
3882,0,0,0,0,0,0,0,13,12,0,0,0,KRT32;keratin 32,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0008544//epidermis development,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
388228,0,0,0,0,0,1,0,0,16,21,7,0,SBK1;SH3 domain binding kinase 1,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
388272,0,1,0,0,30,0,0,0,0,0,0,0,C16orf87;chromosome 16 open reading frame 87,-,-,GO:0005515//protein binding,-
388282,0,0,0,0,0,0,0,0,6,231,0,0,LOC388282;uncharacterized LOC388282,-,-,-,-
388284,0,0,0,0,0,11,0,0,0,0,4,0,C16orf86;chromosome 16 open reading frame 86,-,-,-,-
388289,0,0,0,0,0,0,0,0,34,0,0,0,C16orf47;chromosome 16 open reading frame 47,-,-,-,-
3883,0,0,0,0,0,0,0,0,10,0,0,0,KRT33A;keratin 33A,GO:0005615//extracellular space;GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
388323,1,21,10,25,37,0,0,810,0,0,160,1,GLTPD2;glycolipid transfer protein domain containing 2,GO:0005737//cytoplasm,GO:0046836//glycolipid transport,GO:0017089//glycolipid transporter activity;GO:0051861//glycolipid binding,-
388324,57,197,3,189,272,0,36,136,68,0,467,0,"INCA1;inhibitor of CDK, cyclin A1 interacting protein 1",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:2001235//positive regulation of apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Arginine and proline metabolism;Biotin metabolism;K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
388325,0,23,34,23,35,12,68,0,17,0,46,0,SCIMP;SLP adaptor and CSK interacting membrane protein,GO:0097197//tetraspanin-enriched microdomain;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0031256//leading edge membrane;GO:0001772//immunological synapse;GO:0031259//uropod membrane,GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
388327,0,0,0,0,8,0,0,127,10,0,0,0,C17orf100;chromosome 17 open reading frame 100,-,-,-,-
388333,0,0,0,0,1,0,33,0,21,174,0,0,SPDYE4;speedy/RINGO cell cycle regulator family member E4,-,-,-,K08694//Progesterone-mediated oocyte maturation;Oocyte meiosis
388335,24,66,0,118,46,0,0,126,77,0,32,0,TMEM220;transmembrane protein 220,GO:0016021//integral component of membrane,-,-,-
388336,0,0,0,0,0,15,0,0,98,0,0,0,SHISA6;shisa family member 6,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,-,-,-
388341,0,527,348,551,503,0,49,1,69,1,310,0,LRRC75A;leucine rich repeat containing 75A,-,-,-,-
388387,0,0,0,0,0,0,0,0,0,0,9,0,LINC00671;long intergenic non-protein coding RNA 671,-,-,-,K14443//RNA degradation;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
388389,0,0,0,0,0,0,0,1,9,0,4,0,CCDC103;coiled-coil domain containing 103,GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005930//axoneme,GO:0036159//inner dynein arm assembly;GO:0070286//axonemal dynein complex assembly;GO:0001947//heart looping;GO:0071907//determination of digestive tract left/right asymmetry;GO:0003341//cilium movement;GO:0036158//outer dynein arm assembly;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0030030//cell projection organization,GO:0042803//protein homodimerization activity,K01530//Purine metabolism
388394,28,0,0,0,0,0,0,0,13,0,0,0,RPRML;reprimo-like,GO:0016021//integral component of membrane,-,-,K10128//p53 signaling pathway
3884,0,0,0,0,0,0,12,0,1,0,13,0,KRT33B;keratin 33B,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0042633//hair cycle;GO:0007568//aging,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
388403,107,34,0,15,3,0,26,0,21,0,1,0,YPEL2;yippee-like 2 (Drosophila),GO:0005730//nucleolus,-,-,-
388419,0,0,0,0,0,0,0,0,0,0,17,0,BTBD17;BTB (POZ) domain containing 17,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0009615//response to virus;GO:0045071//negative regulation of viral genome replication,-,K10456//Ubiquitin mediated proteolysis
388428,0,0,0,0,18,0,0,56,13,0,0,0,AATK-AS1;AATK antisense RNA 1,-,-,-,-
388468,4,0,0,0,0,18,3,0,17,9,0,0,"POTEC;POTE ankyrin domain family, member C",-,-,-,-
388499,82,0,0,0,0,0,0,0,10,0,1,0,LYPLA2P2;lysophospholipase II pseudogene 2,-,-,-,K06130//Glycerophospholipid metabolism
3885,0,0,0,0,0,0,0,0,35,0,5,0,KRT34;keratin 34,GO:0005615//extracellular space;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0008544//epidermis development,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
388503,128,0,0,0,0,27,1,0,56,0,14,0,C3P1;complement component 3 precursor pseudogene,GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity,GO:0004866//endopeptidase inhibitor activity,K03990//Staphylococcus aureus infection;Herpes simplex infection;Leishmaniasis;Systemic lupus erythematosus;Complement and coagulation cascades;Legionellosis;Tuberculosis;Pertussis;Phagosome;Chagas disease (American trypanosomiasis)
388507,0,0,0,0,10,16,0,0,21,0,0,0,ZNF788;zinc finger family member 788,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
388512,133,0,0,0,0,39,17,0,34,0,0,0,"CLEC17A;C-type lectin domain family 17, member A",GO:0009986//cell surface;GO:0016021//integral component of membrane,-,GO:0005537//mannose binding;GO:0046872//metal ion binding;GO:0042806//fucose binding,K06563//Phagosome;Measles;Tuberculosis;K04257//Olfactory transduction
388514,1,0,0,0,0,0,36,0,10,0,0,274,"CYP4F24P;cytochrome P450, family 4, subfamily F, polypeptide 24, pseudogene",-,-,-,K00490//Metabolic pathways;Arachidonic acid metabolism
388523,54,0,0,0,0,0,12,0,29,0,9,0,ZNF728;zinc finger protein 728,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
388524,0,1,0,2,2,0,0,0,0,0,0,0,RPSAP58;ribosomal protein SA pseudogene 58,-,-,-,K02998//Ribosome
388531,0,0,0,0,1,0,0,41,0,0,0,0,RGS9BP;regulator of G protein signaling 9 binding protein,GO:0016021//integral component of membrane,"GO:0050908//detection of light stimulus involved in visual perception;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light;GO:0009968//negative regulation of signal transduction",-,-
388533,0,0,0,0,0,0,0,0,12,0,0,0,KRTDAP;keratinocyte differentiation-associated protein,GO:0005576//extracellular region,GO:0030154//cell differentiation,-,-
388536,0,0,0,19,17,0,0,0,17,141,2,0,ZNF790;zinc finger protein 790,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
388550,0,0,0,0,0,5,0,0,27,0,0,0,"CEACAM22P;carcinoembryonic antigen-related cell adhesion molecule 2, pseudogene",-,-,-,-
388551,158,0,0,0,0,7,0,1,12,0,0,0,CEACAM16;carcinoembryonic antigen-related cell adhesion molecule 16,GO:0032426//stereocilium bundle tip;GO:0005576//extracellular region,GO:0007605//sensory perception of sound,-,-
388552,0,0,2,0,0,0,27,295,53,0,0,0,"BLOC1S3;biogenesis of lysosomal organelles complex-1, subunit 3",GO:0030133//transport vesicle;GO:0031083//BLOC-1 complex;GO:0005829//cytosol,GO:0060155//platelet dense granule organization;GO:0048490//anterograde synaptic vesicle transport;GO:0032438//melanosome organization;GO:0061024//membrane organization;GO:0006892//post-Golgi vesicle-mediated transport;GO:0035646//endosome to melanosome transport;GO:0032816//positive regulation of natural killer cell activation;GO:0001654//eye development;GO:0031175//neuron projection development;GO:0032402//melanosome transport;GO:0030168//platelet activation;GO:0008089//anterograde axon cargo transport;GO:0043473//pigmentation;GO:0042493//response to drug;GO:0033299//secretion of lysosomal enzymes,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer
388555,0,0,0,0,0,0,0,0,23,0,0,0,IGFL3;IGF-like family member 3,GO:0005576//extracellular region,-,-,-
388558,0,0,0,8,18,0,0,51,14,0,0,0,ZNF808;zinc finger protein 808,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
388561,0,95,1,183,512,0,34,0,38,0,0,0,ZNF761;zinc finger protein 761,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
388566,0,0,0,0,81,8,0,1,50,0,0,0,ZNF470;zinc finger protein 470,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
388567,0,19,0,0,4,0,0,0,0,0,0,0,ZNF749;zinc finger protein 749,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
388569,0,24,0,0,0,0,0,0,0,0,0,0,ZNF324B;zinc finger protein 324B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
388574,0,0,0,0,0,0,41,0,3,1,2,10,FLJ43681;ribosomal protein L23a pseudogene,-,-,-,K02893//Ribosome
388581,0,0,0,0,0,0,0,47,13,0,0,0,"FAM132A;family with sequence similarity 132, member A",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0050728//negative regulation of inflammatory response;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0046324//regulation of glucose import;GO:0046326//positive regulation of glucose import;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045721//negative regulation of gluconeogenesis,GO:0005179//hormone activity,-
388585,0,0,0,0,0,0,0,0,10,0,0,0,HES5;hes family bHLH transcription factor 5,GO:0005654//nucleoplasm,"GO:0006461//protein complex assembly;GO:0008284//positive regulation of cell proliferation;GO:0048469//cell maturation;GO:0043010//camera-type eye development;GO:0051216//cartilage development;GO:0042668//auditory receptor cell fate determination;GO:2000737//negative regulation of stem cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0007420//brain development;GO:0097150//neuronal stem cell maintenance;GO:0031641//regulation of myelination;GO:0048708//astrocyte differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:2000978//negative regulation of forebrain neuron differentiation;GO:0021861//forebrain radial glial cell differentiation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007224//smoothened signaling pathway;GO:0072282//metanephric nephron tubule morphogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0021537//telencephalon development;GO:2000974//negative regulation of pro-B cell differentiation;GO:0021781//glial cell fate commitment;GO:0045595//regulation of cell differentiation;GO:0007155//cell adhesion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002062//chondrocyte differentiation;GO:0046427//positive regulation of JAK-STAT cascade;GO:0014003//oligodendrocyte development;GO:0042491//auditory receptor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021915//neural tube development;GO:0007219//Notch signaling pathway;GO:2000981//negative regulation of inner ear receptor cell differentiation;GO:0022010//central nervous system myelination;GO:0050767//regulation of neurogenesis;GO:0045747//positive regulation of Notch signaling pathway",GO:0008134//transcription factor binding;GO:0003690//double-stranded DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding,K06055//Notch signaling pathway
388588,0,0,0,0,0,0,19,0,3,0,5,0,SMIM1;small integral membrane protein 1 (Vel blood group),GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
388591,0,17,0,0,8,14,18,0,59,0,7,0,RNF207;ring finger protein 207,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
388595,0,0,0,0,0,0,21,0,17,0,0,0,TMEM82;transmembrane protein 82,GO:0016021//integral component of membrane,-,-,-
3886,78,0,0,0,3,0,16,0,0,0,13,0,KRT35;keratin 35,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0009653//anatomical structure morphogenesis,GO:0005198//structural molecule activity,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
388610,9,0,0,0,0,0,0,0,0,0,0,0,TRNP1;TMF1-regulated nuclear protein 1,GO:0005719//nuclear euchromatin;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0021696//cerebellar cortex morphogenesis;GO:0061351//neural precursor cell proliferation;GO:0042127//regulation of cell proliferation;GO:0007049//cell cycle;GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
388611,0,0,0,0,0,0,3,22,8,0,0,0,CD164L2;CD164 sialomucin-like 2,GO:0016021//integral component of membrane,-,-,K06546//Lysosome
388630,80,0,0,0,0,0,0,0,28,46,4,0,TRABD2B;TraB domain containing 2B,GO:0031301//integral component of organelle membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0016055//Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008152//metabolic process;GO:0006508//proteolysis;GO:0018158//protein oxidation,GO:0017147//Wnt-protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004222//metalloendopeptidase activity,-
388633,144,0,0,3,0,0,14,0,27,0,6,0,LDLRAD1;low density lipoprotein receptor class A domain containing 1,GO:0016021//integral component of membrane,-,-,K06233//Hedgehog signaling pathway;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
388646,0,37,0,0,0,0,0,1,0,42,0,0,GBP7;guanylate binding protein 7,GO:0016020//membrane,GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
388650,83,0,0,0,0,0,0,1,0,0,40,0,"FAM69A;family with sequence similarity 69, member A",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
388662,0,0,40,0,0,0,38,0,26,0,30,0,"SLC6A17;solute carrier family 6 (neutral amino acid transporter), member 17",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle,GO:0032328//alanine transport;GO:0055085//transmembrane transport;GO:0006836//neurotransmitter transport;GO:0015816//glycine transport;GO:0015804//neutral amino acid transport;GO:0015824//proline transport;GO:0015820//leucine transport,GO:0005328//neurotransmitter:sodium symporter activity,-
388677,100,80,20,7,282,1,67,69,30,106,1,269,NOTCH2NL;notch 2 N-terminal like,GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0030154//cell differentiation;GO:0007219//Notch signaling pathway;GO:0007275//multicellular organismal development,GO:0005509//calcium ion binding,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
388685,0,33,1,72,108,0,0,63,46,0,102,0,LINC01138;long intergenic non-protein coding RNA 1138,-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
388695,0,0,0,0,0,33,0,0,0,0,13,404,"LYSMD1;LysM, putative peptidoglycan-binding, domain containing 1",-,-,-,-
388697,125,313,153,80,192,19,79,406,101,1,390,1,HRNR;hornerin,GO:0001533//cornified envelope;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0031424//keratinization;GO:0061436//establishment of skin barrier;GO:0002244//hematopoietic progenitor cell differentiation,GO:0005509//calcium ion binding,-
388698,25,0,0,0,0,10,46,0,53,0,11,0,FLG2;filaggrin family member 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0061436//establishment of skin barrier,GO:0005509//calcium ion binding;GO:0005198//structural molecule activity,-
3887,0,0,0,0,0,7,0,0,0,0,0,0,KRT81;keratin 81,GO:0045095//keratin filament;GO:0005615//extracellular space,-,GO:0005198//structural molecule activity;GO:0005515//protein binding,-
388714,0,0,0,0,0,40,0,0,0,0,11,0,FMO6P;flavin containing monooxygenase 6 pseudogene,-,-,-,K00485//Drug metabolism - cytochrome P450;Microbial metabolism in diverse environments;Methane metabolism
388730,37,0,0,0,0,0,0,0,0,0,0,0,TMEM81;transmembrane protein 81,GO:0016021//integral component of membrane,-,-,-
388743,0,0,0,4,0,38,1,0,58,0,0,0,CAPN8;calpain 8,GO:0005737//cytoplasm;GO:0005794//Golgi apparatus,GO:0007586//digestion;GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
388759,0,25,0,5,8,2,0,0,14,0,0,0,C1orf229;chromosome 1 open reading frame 229,-,-,-,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
388762,0,0,0,0,0,0,0,0,11,0,0,0,"OR2M1P;olfactory receptor, family 2, subfamily M, member 1 pseudogene",-,-,-,K04257//Olfactory transduction
388780,0,17,0,0,0,0,0,65,0,0,0,0,LOC388780;uncharacterized LOC388780,-,-,-,-
388789,0,0,0,7,40,0,0,0,0,0,0,0,LINC00493;long intergenic non-protein coding RNA 493,-,-,-,-
388796,0,0,0,0,0,0,0,45,0,0,0,1,SNHG17;small nucleolar RNA host gene 17 (non-protein coding),-,-,-,-
388799,0,0,0,0,0,0,0,0,19,0,0,0,"FAM209B;family with sequence similarity 209, member B",GO:0016021//integral component of membrane;GO:0005634//nucleus,-,-,-
3888,309,0,0,0,0,17,41,0,13,0,0,2,KRT82;keratin 82,GO:0045095//keratin filament,-,GO:0030280//structural constituent of epidermis,-
388813,0,0,0,0,0,12,11,0,26,0,0,0,LOC388813;uncharacterized protein ENSP00000383407-like,-,-,-,-
388849,0,0,0,0,7,27,0,0,0,0,0,0,LOC388849;uncharacterized LOC388849,-,-,-,-
388882,0,0,0,0,0,32,0,0,15,0,9,0,LOC388882;uncharacterized LOC388882,-,-,-,-
388886,0,0,0,0,1,0,0,51,28,0,0,0,LRRC75B;leucine rich repeat containing 75B,-,-,-,-
3889,0,0,0,0,0,0,0,0,61,0,12,0,KRT83;keratin 83,GO:0005615//extracellular space;GO:0045095//keratin filament,GO:0007568//aging;GO:0008544//epidermis development;GO:0042633//hair cycle,GO:0005198//structural molecule activity,-
388931,0,0,0,0,0,0,15,0,35,0,0,0,MFSD2B;major facilitator superfamily domain containing 2B,GO:0016021//integral component of membrane,GO:0006810//transport,-,-
388939,0,0,0,0,11,18,21,202,63,86,2,0,C2orf71;chromosome 2 open reading frame 71,GO:0072372//primary cilium;GO:0001750//photoreceptor outer segment,GO:0050896//response to stimulus;GO:0007601//visual perception,-,K11422//Lysine degradation;K05746//Regulation of actin cytoskeleton
388942,0,0,0,0,0,0,27,0,0,0,1,0,LOC388942;uncharacterized LOC388942,-,-,-,-
388946,0,0,0,0,0,26,10,0,9,0,0,83,TMEM247;transmembrane protein 247,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,-,-
388951,17,0,0,0,0,20,3,71,2,1,0,0,TSPYL6;TSPY-like 6,GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
388960,94,0,0,0,0,0,0,1,0,0,0,0,C2orf78;chromosome 2 open reading frame 78,-,-,-,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
388962,0,0,0,0,0,0,0,0,17,0,0,0,BOLA3;bolA family member 3,GO:0005576//extracellular region,-,-,-
388963,0,0,0,25,13,0,0,314,71,243,41,0,C2orf81;chromosome 2 open reading frame 81,-,-,-,-
388965,0,0,1,0,0,40,0,0,0,0,0,0,FUNDC2P2;FUN14 domain containing 2 pseudogene 2,-,-,-,-
388969,0,3,0,8,2,15,53,0,8,0,0,0,C2orf68;chromosome 2 open reading frame 68,-,-,-,K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
389,0,56,4,72,86,0,102,10,30,0,97,0,RHOC;ras homolog family member C,GO:0032154//cleavage furrow;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043297//apical junction assembly;GO:0007411//axon guidance;GO:0000910//cytokinesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding;GO:0004871//signal transducer activity,-
3890,0,0,0,0,0,0,0,0,0,0,0,341,KRT84;keratin 84,GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament,GO:0001942//hair follicle development;GO:0045616//regulation of keratinocyte differentiation;GO:0035878//nail development,GO:0030280//structural constituent of epidermis;GO:0005200//structural constituent of cytoskeleton,-
389015,0,0,0,0,0,9,0,0,56,0,8,0,"SLC9A4;solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4",GO:0016324//apical plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006811//ion transport;GO:0002064//epithelial cell development;GO:1902600//hydrogen ion transmembrane transport;GO:0001696//gastric acid secretion;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0006885//regulation of pH,GO:0015385//sodium:proton antiporter activity,K13961//Gastric acid secretion
389058,0,0,0,12,0,0,0,0,0,0,0,0,SP5;Sp5 transcription factor,GO:0005634//nucleus,"GO:0060349//bone morphogenesis;GO:0006351//transcription, DNA-templated;GO:0036342//post-anal tail morphogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
389072,0,0,0,3,43,10,3,0,19,0,2,0,"PLEKHM3;pleckstrin homology domain containing, family M, member 3",-,GO:0035556//intracellular signal transduction,GO:0046872//metal ion binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
389073,0,0,0,0,0,17,0,0,0,104,0,0,C2orf80;chromosome 2 open reading frame 80,-,-,-,-
3891,0,0,0,0,0,0,12,0,0,0,0,0,KRT85;keratin 85,GO:0005615//extracellular space;GO:0045095//keratin filament,GO:0008544//epidermis development,GO:0005198//structural molecule activity,-
389114,0,0,0,0,0,0,48,0,59,0,24,0,ZNF662;zinc finger protein 662,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
389118,0,0,0,0,0,0,0,0,35,0,0,0,CDHR4;cadherin-related family member 4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
389119,0,0,0,0,0,0,0,0,0,71,3,0,"FAM212A;family with sequence similarity 212, member A",GO:0070062//extracellular vesicular exosome,GO:0021915//neural tube development,-,-
389123,0,0,0,0,0,0,13,0,3,0,1,0,IQCF2;IQ motif containing F2,-,-,-,-
389124,0,0,0,0,0,0,0,0,4,0,0,0,IQCF5;IQ motif containing F5,-,-,-,-
389125,17,0,0,0,0,18,0,0,11,0,0,0,"MUSTN1;musculoskeletal, embryonic nuclear protein 1",GO:0005634//nucleus,-,-,-
389136,9,102,12,402,1221,38,21,0,11,0,6,0,VGLL3;vestigial-like family member 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
389151,0,0,0,0,0,0,0,0,26,0,0,0,PRR23B;proline rich 23B,-,-,-,-
389152,0,0,53,0,0,10,0,0,0,0,0,0,PRR23C;proline rich 23C,-,-,-,K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K09057//Circadian rhythm - fly
389158,0,0,0,0,0,0,0,0,11,0,0,0,"PLSCR5;phospholipid scramblase family, member 5",-,-,-,K08267//mTOR signaling pathway
389161,0,0,24,0,0,0,2,0,12,0,0,0,ANKUB1;ankyrin repeat and ubiquitin domain containing 1,-,-,-,-
389170,0,0,0,0,0,0,0,0,72,0,23,0,"LEKR1;leucine, glutamate and lysine rich 1",-,-,-,-
389177,0,0,0,0,0,26,0,0,2,0,0,0,TMEM212;transmembrane protein 212,GO:0016021//integral component of membrane,-,-,K04257//Olfactory transduction;K00543//Metabolic pathways;Tryptophan metabolism;K09299//Transcriptional misregulation in cancer
3892,89,0,0,0,0,11,0,0,39,0,1,0,KRT86;keratin 86,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
389203,0,0,0,0,15,0,0,0,3,0,3,0,SMIM20;small integral membrane protein 20,GO:0016021//integral component of membrane,-,-,-
389206,0,37,0,29,106,0,16,0,42,0,11,1,BEND4;BEN domain containing 4,-,-,-,-
389207,0,0,0,0,0,0,0,0,36,0,0,0,"GRXCR1;glutaredoxin, cysteine rich 1",GO:0032420//stereocilium;GO:0060091//kinocilium,GO:0010923//negative regulation of phosphatase activity;GO:0007605//sensory perception of sound;GO:0042491//auditory receptor cell differentiation;GO:0060119//inner ear receptor cell development;GO:0060122//inner ear receptor stereocilium organization;GO:0060118//vestibular receptor cell development;GO:0048563//post-embryonic organ morphogenesis;GO:0055114//oxidation-reduction process;GO:0045454//cell redox homeostasis,GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity,-
389208,0,0,0,9,0,8,21,0,58,1,0,0,"TMPRSS11F;transmembrane protease, serine 11F",GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
389289,0,0,0,0,17,37,0,0,1,1,5,0,ANXA2R;annexin A2 receptor,-,-,-,-
389332,0,0,0,0,26,0,0,0,0,0,8,0,LOC389332;uncharacterized LOC389332,-,-,-,-
389333,0,138,64,85,181,27,0,960,146,0,475,0,PROB1;proline-rich basic protein 1,-,-,-,-
389337,0,4,1,6,90,25,68,1,75,0,103,0,ARHGEF37;Rho guanine nucleotide exchange factor (GEF) 37,GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12365//Chemokine signaling pathway
389362,0,0,0,0,1,0,0,0,0,0,0,0,"PSMG4;proteasome (prosome, macropain) assembly chaperone 4",-,-,-,-
389384,0,0,0,0,0,0,27,0,35,0,0,0,C6orf222;chromosome 6 open reading frame 222,-,-,-,K03211//MAPK signaling pathway - fly;Dorso-ventral axis formation;Transcriptional misregulation in cancer;K04574//Amyotrophic lateral sclerosis (ALS)
389396,0,0,0,0,0,9,0,1,26,0,0,0,GLYATL3;glycine-N-acyltransferase-like 3,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0047961//glycine N-acyltransferase activity,K15517//Phenylalanine metabolism;K00628//Phenylalanine metabolism
389400,0,0,0,0,0,20,0,0,20,0,0,0,GFRAL;GDNF family receptor alpha like,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0031098//stress-activated protein kinase signaling cascade;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043524//negative regulation of neuron apoptotic process,-,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
389421,0,0,0,0,0,1,0,0,66,0,0,0,LIN28B;lin-28 homolog B (C. elegans),GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0031123//RNA 3'-end processing;GO:0010587//miRNA catabolic process;GO:0031054//pre-miRNA processing;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,-
389432,0,0,0,1,0,9,6,0,6,0,0,0,SAMD5;sterile alpha motif domain containing 5,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
389434,78,0,0,0,0,0,0,0,29,0,0,1,IYD;iodotyrosine deiodinase,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055114//oxidation-reduction process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006590//thyroid hormone generation;GO:0044281//small molecule metabolic process,GO:0004447//iodide peroxidase activity;GO:0016491//oxidoreductase activity,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K07987//Natural killer cell mediated cytotoxicity;K11447//Transcriptional misregulation in cancer
389493,0,0,0,21,55,22,0,0,0,0,0,0,"NUPR1L;nuclear protein, transcriptional regulator, 1-like",-,-,-,K15626//Transcriptional misregulation in cancer
3895,0,0,18,15,3,0,0,0,57,6,1,0,KTN1;kinectin 1 (kinesin receptor),GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007018//microtubule-based movement,GO:0019894//kinesin binding;GO:0044822//poly(A) RNA binding,K14000//Protein processing in endoplasmic reticulum
389538,0,0,0,0,5,0,0,0,31,0,0,0,MGC72080;MGC72080 pseudogene,-,-,-,K04257//Olfactory transduction
389541,0,23,0,0,0,0,0,0,0,0,0,0,"LAMTOR4;late endosomal/lysosomal adaptor, MAPK and MTOR activator 4",GO:0005764//lysosome;GO:0043231//intracellular membrane-bounded organelle;GO:0071986//Ragulator complex,GO:0071230//cellular response to amino acid stimulus;GO:0008361//regulation of cell size;GO:0043547//positive regulation of GTPase activity;GO:0061462//protein localization to lysosome;GO:0032008//positive regulation of TOR signaling,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032947//protein complex scaffold,-
389549,0,0,0,0,0,13,0,59,20,102,0,0,FEZF1;FEZ family zinc finger 1,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045666//positive regulation of neuron differentiation;GO:0001764//neuron migration;GO:0021772//olfactory bulb development;GO:0006351//transcription, DNA-templated;GO:0021797//forebrain anterior/posterior pattern specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0007411//axon guidance",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046872//metal ion binding,-
389558,0,0,0,0,0,0,0,0,2,0,0,0,"FAM180A;family with sequence similarity 180, member A",GO:0005576//extracellular region,-,-,-
389602,0,0,0,0,0,0,0,0,11,0,2,0,LOC389602;uncharacterized LOC389602,-,-,-,-
389610,87,0,0,0,0,0,22,0,9,0,0,0,"XKR5;XK, Kell blood group complex subunit-related family, member 5",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
389633,0,0,0,0,0,0,0,3,0,0,0,0,"FAM90A25P;family with sequence similarity 90, member A7 pseudogene",-,-,-,-
389634,0,0,0,0,0,0,0,0,0,0,1,0,LINC00937;long intergenic non-protein coding RNA 937,-,-,-,-
389643,0,0,0,0,0,0,2,38,50,0,0,0,"NUGGC;nuclear GTPase, germinal center associated",GO:0005634//nucleus,GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006184//GTP catabolic process;GO:0006974//cellular response to DNA damage stimulus,GO:0003924//GTPase activity;GO:0005525//GTP binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
389649,0,0,0,0,0,23,0,0,0,0,0,0,C8orf86;chromosome 8 open reading frame 86,-,-,-,K11447//Transcriptional misregulation in cancer;K14443//RNA degradation;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
389658,0,0,0,0,0,0,0,0,30,0,0,0,"FAM150A;family with sequence similarity 150, member A",GO:0005576//extracellular region,-,-,-
389668,0,0,0,0,0,14,0,0,22,0,0,0,"XKR9;XK, Kell blood group complex subunit-related family, member 9",GO:0016021//integral component of membrane,-,-,K09299//Transcriptional misregulation in cancer;K00543//Tryptophan metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K04257//Olfactory transduction;K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
389676,1,0,0,0,0,0,0,0,8,0,0,0,C8orf87;chromosome 8 open reading frame 87,-,-,-,-
389677,0,0,3,7,23,0,13,0,0,0,1,0,RBM12B;RNA binding motif protein 12B,-,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
389690,50,0,1,0,0,38,22,7,36,0,6,0,MROH5;maestro heat-like repeat family member 5,-,-,-,K14398//mRNA surveillance pathway
389692,0,0,0,0,0,0,0,0,15,0,0,0,MAFA;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007263//nitric oxide mediated signal transduction;GO:0030073//insulin secretion;GO:0009749//response to glucose;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K07595//Maturity onset diabetes of the young;Type II diabetes mellitus
3897,0,0,0,0,0,19,62,0,15,0,9,0,L1CAM;L1 cell adhesion molecule,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0043195//terminal bouton,GO:0050900//leukocyte migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007159//leukocyte cell-cell adhesion;GO:0034109//homotypic cell-cell adhesion;GO:0050850//positive regulation of calcium-mediated signaling;GO:0033631//cell-cell adhesion mediated by integrin;GO:0008219//cell death;GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007155//cell adhesion;GO:0022409//positive regulation of cell-cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0006935//chemotaxis,GO:0042802//identical protein binding;GO:0005178//integrin binding;GO:0033691//sialic acid binding;GO:0043621//protein self-association,K06550//Axon guidance;Cell adhesion molecules (CAMs)
389715,83,0,0,0,0,0,29,2,22,0,43,0,FAM205B;transmembrane protein C9orf144B pseudogene,-,-,-,-
389730,0,0,0,0,0,0,0,1,0,0,0,0,"SPATA31A6;SPATA31 subfamily A, member 6",GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
389761,80,0,57,0,0,33,0,3,1,0,0,6,"SPATA31D4;SPATA31 subfamily D, member 4",GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
389763,105,0,0,0,0,9,6,0,42,66,6,0,"SPATA31D1;SPATA31 subfamily D, member 1",GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007283//spermatogenesis,-,-
389765,1,0,11,0,41,0,0,0,36,0,0,0,LOC389765;kinesin family member 27 pseudogene,-,-,-,-
389766,0,0,0,0,0,10,0,0,24,0,0,0,C9orf153;chromosome 9 open reading frame 153,-,-,-,-
389791,1,0,0,0,0,7,0,0,8,0,3,0,PTGES2-AS1;PTGES2 antisense RNA 1 (head to head),GO:0016021//integral component of membrane,-,-,K07987//Natural killer cell mediated cytotoxicity
389792,0,0,0,0,0,0,0,0,2,0,20,0,IER5L;immediate early response 5-like,-,-,-,-
389799,0,0,0,0,0,0,0,0,4,18,0,0,C9orf171;chromosome 9 open reading frame 171,-,-,-,-
3898,0,18,0,18,7,17,0,148,6,0,55,0,LAD1;ladinin 1,GO:0005604//basement membrane,-,GO:0005198//structural molecule activity,K04573//Amyotrophic lateral sclerosis (ALS);K04574//Amyotrophic lateral sclerosis (ALS)
389812,0,0,0,0,0,0,0,0,7,0,2,0,LCN15;lipocalin 15,GO:0005576//extracellular region,GO:0006810//transport;GO:0006629//lipid metabolic process,GO:0036094//small molecule binding;GO:0005215//transporter activity,K01830//Metabolic pathways;Arachidonic acid metabolism
389813,0,0,0,0,0,0,0,51,40,0,0,0,C9orf172;chromosome 9 open reading frame 172,-,-,-,-
389816,0,0,0,0,0,0,0,0,14,0,0,0,LRRC26;leucine rich repeat containing 26,GO:0070062//extracellular vesicular exosome;GO:0008076//voltage-gated potassium channel complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0006811//ion transport,GO:0005515//protein binding;GO:0015459//potassium channel regulator activity,K06839//Axon guidance;K06838//Axon guidance;K06260//Hematopoietic cell lineage;ECM-receptor interaction
389827,58,0,0,0,0,26,0,0,19,0,0,0,TMEM8C;transmembrane protein 8C,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007517//muscle organ development;GO:0045026//plasma membrane fusion;GO:0007520//myoblast fusion,-,-
389831,0,0,0,0,17,0,0,0,60,0,0,0,LOC389831;uncharacterized LOC389831,-,-,-,-
389834,25,0,0,22,9,17,35,0,41,40,0,0,LOC389834;ankyrin repeat domain 57 pseudogene,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
389840,0,28,95,112,233,8,15,0,58,0,150,0,MAP3K15;mitogen-activated protein kinase kinase kinase 15,-,GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0000186//activation of MAPKK activity,GO:0046872//metal ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding,-
389856,0,0,0,0,24,0,0,0,17,0,0,0,"USP27X;ubiquitin specific peptidase 27, X-linked",-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
389860,77,0,0,0,0,0,0,0,0,0,0,0,"PAGE2B;P antigen family, member 2B",-,-,-,-
389874,0,0,0,0,0,0,31,0,22,0,0,0,"ZCCHC13;zinc finger, CCHC domain containing 13",-,-,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,-
389895,0,0,0,0,0,0,0,0,16,0,0,0,LOC389895;chromosome 16 open reading frame 72-like,-,-,-,-
3899,0,126,1,165,458,41,6,0,68,0,16,0,"AFF3;AF4/FMR2 family, member 3",GO:0005634//nucleus,"GO:0035116//embryonic hindlimb morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0034612//response to tumor necrosis factor",GO:0003690//double-stranded DNA binding,-
389906,0,0,0,0,0,0,0,132,23,0,0,0,LOC389906;zinc finger protein 839 pseudogene,-,-,-,-
389932,0,0,62,0,0,30,0,0,24,0,0,0,"AKR1C6P;aldo-keto reductase family 1, member C6, pseudogene",-,-,-,K05295//Steroid hormone biosynthesis;K00212//Arachidonic acid metabolism;Metabolic pathways;Primary bile acid biosynthesis;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00089//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Metabolic pathways;Primary bile acid biosynthesis;Arachidonic acid metabolism
389941,201,28,113,1,125,0,0,0,7,132,0,0,"C1QL3;complement component 1, q subcomponent-like 3",GO:0005581//collagen trimer;GO:0005576//extracellular region,GO:0050807//regulation of synapse organization,-,K07296//Type II diabetes mellitus;PPAR signaling pathway;Adipocytokine signaling pathway
39,0,115,115,104,331,5,74,0,12,258,107,0,ACAT2;acetyl-CoA acetyltransferase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0006629//lipid metabolic process,GO:0003985//acetyl-CoA C-acetyltransferase activity,"K00626//Fat digestion and absorption;Carbon fixation pathways in prokaryotes;Valine, leucine and isoleucine degradation;Butanoate metabolism;Fatty acid metabolism;Lysine degradation;Propanoate metabolism;Aminoacyl-tRNA biosynthesis;Pyruvate metabolism;Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Two-component system;Tryptophan metabolism;Biosynthesis of secondary metabolites;Synthesis and degradation of ketone bodies;Microbial metabolism in diverse environments;Terpenoid backbone biosynthesis;Benzoate degradation"
390,94,0,0,0,18,0,0,0,21,0,0,0,RND3;Rho family GTPase 3,GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,GO:0007155//cell adhesion;GO:0007264//small GTPase mediated signal transduction;GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,-
390003,39,0,0,0,0,1,0,0,26,0,0,0,"GUCY2GP;guanylate cyclase 2G, pseudogene",-,-,-,K12323//Purine metabolism;Vascular smooth muscle contraction;K12321//Phototransduction;Olfactory transduction;Purine metabolism
390010,0,0,0,0,0,0,0,0,21,0,0,0,NKX1-2;NK1 homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0043565//sequence-specific DNA binding,-
390036,86,0,0,0,0,0,0,0,0,0,0,0,"OR52K1;olfactory receptor, family 52, subfamily K, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390038,0,0,0,0,0,0,0,0,13,0,0,0,"OR51D1;olfactory receptor, family 51, subfamily D, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390059,0,0,0,0,0,0,0,0,12,0,0,0,"OR51M1;olfactory receptor, family 51, subfamily M, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390061,0,0,0,0,0,0,0,0,33,0,0,0,"OR51Q1;olfactory receptor, family 51, subfamily Q, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390063,0,0,0,0,0,0,0,0,0,0,1,0,"OR51I1;olfactory receptor, family 51, subfamily I, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390064,0,0,0,0,0,0,0,0,16,0,0,0,"OR51I2;olfactory receptor, family 51, subfamily I, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390066,0,0,0,0,0,0,0,0,10,0,0,0,"OR52D1;olfactory receptor, family 52, subfamily D, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390067,0,0,0,0,0,0,28,0,0,0,0,0,"OR52H1;olfactory receptor, family 52, subfamily H, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390072,0,0,0,0,0,0,0,0,14,0,0,0,"OR52N4;olfactory receptor, family 52, subfamily N, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390081,0,0,0,0,0,0,0,0,15,0,0,0,"OR52E4;olfactory receptor, family 52, subfamily E, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390083,78,0,0,0,0,0,0,28,0,0,0,0,"OR56A3;olfactory receptor, family 56, subfamily A, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390084,0,0,0,0,0,0,0,0,53,0,0,0,"OR56A5;olfactory receptor, family 56, subfamily A, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390093,0,0,0,0,0,0,0,0,1,0,0,0,"OR10A6;olfactory receptor, family 10, subfamily A, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390110,0,0,0,0,0,0,20,0,31,0,0,0,ACCSL;1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like,-,GO:0009058//biosynthetic process,GO:0003824//catalytic activity;GO:0030170//pyridoxal phosphate binding,"K00815//Phenylalanine, tyrosine and tryptophan biosynthesis;Isoquinoline alkaloid biosynthesis;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Tropane, piperidine and pyridine alkaloid biosynthesis;Tyrosine metabolism;Phenylalanine metabolism;Ubiquinone and other terpenoid-quinone biosynthesis;K00816//Metabolic pathways;Tryptophan metabolism;Selenocompound metabolism"
390144,0,0,0,0,0,0,0,0,7,0,0,0,"OR5D16;olfactory receptor, family 5, subfamily D, member 16",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390148,0,0,0,0,0,0,0,0,29,0,0,0,"OR5W2;olfactory receptor, family 5, subfamily W, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390154,92,0,0,0,0,0,0,0,0,0,0,0,"OR5T3;olfactory receptor, family 5, subfamily T, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390155,0,0,0,0,0,0,0,0,8,0,0,0,"OR5T1;olfactory receptor, family 5, subfamily T, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390157,0,0,0,0,0,0,0,0,21,0,0,0,"OR8K1;olfactory receptor, family 8, subfamily K, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390167,0,0,0,0,0,0,2,0,29,0,0,0,"OR5M10;olfactory receptor, family 5, subfamily M, member 10",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390181,0,0,0,0,0,28,0,0,12,0,0,0,"OR5AK2;olfactory receptor, family 5, subfamily AK, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390190,0,0,0,0,0,13,0,0,4,0,0,0,"OR5B2;olfactory receptor, family 5, subfamily B, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390195,0,0,0,0,0,0,0,0,13,0,0,0,"OR5AN1;olfactory receptor, family 5, subfamily AN, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390197,0,0,0,0,0,0,0,0,33,0,0,0,"OR4D10;olfactory receptor, family 4, subfamily D, member 10",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390199,169,0,0,0,0,0,0,0,0,0,0,0,"OR4D9;olfactory receptor, family 4, subfamily D, member 9",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3902,0,0,0,0,0,17,0,0,36,0,15,0,LAG3;lymphocyte-activation gene 3,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0045085//negative regulation of interleukin-2 biosynthetic process,GO:0042289//MHC class II protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0003823//antigen binding,-
390201,0,0,0,0,0,0,0,0,7,0,0,0,"OR10V1;olfactory receptor, family 10, subfamily V, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390205,0,0,0,0,0,0,0,0,11,0,0,0,LRRC10B;leucine rich repeat containing 10B,-,-,-,K12796//NOD-like receptor signaling pathway
390212,0,0,0,27,42,0,0,37,28,0,50,197,GPR152;G protein-coupled receptor 152,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
390226,0,0,0,0,0,9,33,0,8,0,0,228,"GUCY2EP;guanylate cyclase 2E, pseudogene",-,-,-,K12321//Phototransduction;Olfactory transduction;Purine metabolism
390231,90,0,0,0,0,18,0,0,0,0,0,0,TRIM77;tripartite motif containing 77,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
390245,0,0,0,20,49,27,0,2,3,0,29,0,KDM4E;lysine (K)-specific demethylase 4E,GO:0005634//nucleus,"GO:0033169//histone H3-K9 demethylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0055114//oxidation-reduction process",GO:0051213//dioxygenase activity;GO:0046872//metal ion binding,-
390259,0,0,0,0,0,2,0,105,0,0,0,0,BSX;brain-specific homeobox,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0060056//mammary gland involution;GO:0042755//eating behavior;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
390260,0,0,0,0,0,19,0,0,0,0,0,0,"OR6X1;olfactory receptor, family 6, subfamily X, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390265,0,0,0,0,0,0,0,0,18,0,8,0,"OR10G7;olfactory receptor, family 10, subfamily G, member 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3903,74,0,0,0,0,0,28,1,49,0,0,309,LAIR1;leukocyte-associated immunoglobulin-like receptor 1,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0002376//immune system process,GO:0005515//protein binding,-
390321,0,0,0,0,0,0,16,0,0,0,0,0,"OR6C1;olfactory receptor, family 6, subfamily C, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390323,0,0,0,0,0,0,0,0,22,0,0,0,"OR6C75;olfactory receptor, family 6, subfamily C, member 75",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390326,0,0,0,0,0,29,0,0,12,0,0,0,"OR6C76;olfactory receptor, family 6, subfamily C, member 76",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390327,82,0,0,0,0,0,0,0,14,0,0,0,"OR6C70;olfactory receptor, family 6, subfamily C, member 70",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3904,0,0,0,0,0,0,0,0,0,0,0,14,LAIR2;leukocyte-associated immunoglobulin-like receptor 2,GO:0005576//extracellular region,-,-,-
390429,0,0,0,0,0,36,0,0,10,0,0,0,"OR4N2;olfactory receptor, family 4, subfamily N, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390431,0,0,0,0,0,0,0,39,0,0,0,0,"OR4K2;olfactory receptor, family 4, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390439,0,0,0,0,0,0,0,0,17,0,0,0,"OR11G2;olfactory receptor, family 11, subfamily G, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390442,0,0,0,0,0,0,0,40,35,0,0,0,"OR11H4;olfactory receptor, family 11, subfamily H, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390445,0,0,0,0,0,0,0,0,11,0,0,0,"OR5AU1;olfactory receptor, family 5, subfamily AU, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390502,0,0,0,0,0,0,88,0,33,0,0,0,"SERPINA2;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)",GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K03984//Complement and coagulation cascades
390535,0,0,0,0,0,0,12,0,30,0,0,0,"GOLGA8EP;golgin A8 family, member E, pseudogene",-,-,-,-
390538,0,0,0,0,0,0,0,0,0,0,3,0,"OR4M2;olfactory receptor, family 4, subfamily M, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390539,0,0,0,0,0,0,45,0,33,0,0,0,"OR4N3P;olfactory receptor, family 4, subfamily N, member 3 pseudogene",-,-,-,K04257//Olfactory transduction
390561,0,0,0,0,0,0,13,0,12,0,0,0,HERC2P10;hect domain and RLD 2 pseudogene 10,-,-,-,K10595//Ubiquitin mediated proteolysis
390594,0,0,0,0,0,0,0,134,19,0,6,1,KBTBD13;kelch repeat and BTB (POZ) domain containing 13,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,-,K10447//Ubiquitin mediated proteolysis
390595,0,0,0,0,0,2,0,0,0,0,0,0,UBAP1L;ubiquitin associated protein 1-like,-,-,-,-
390598,0,0,0,0,0,0,0,0,10,0,8,0,SKOR1;SKI family transcriptional corepressor 1,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0030425//dendrite,"GO:0006351//transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0030514//negative regulation of BMP signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0046332//SMAD binding,-
390616,0,0,0,0,0,85,29,0,11,0,0,0,ANKRD34C;ankyrin repeat domain 34C,-,-,-,-
390637,0,0,1,0,0,2,1,0,18,0,0,339,GDPGP1;GDP-D-glucose phosphorylase 1,GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0006006//glucose metabolic process,GO:0080048//GDP-D-glucose phosphorylase activity;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0016787//hydrolase activity;GO:0016779//nucleotidyltransferase activity;GO:0000166//nucleotide binding,-
390648,0,0,0,0,0,0,0,0,0,0,6,0,"OR4F6;olfactory receptor, family 4, subfamily F, member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390649,0,0,0,0,0,4,0,0,13,0,0,0,"OR4F15;olfactory receptor, family 4, subfamily F, member 15",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390651,0,0,0,0,0,0,0,0,20,0,0,0,"OR4F13P;olfactory receptor, family 4, subfamily F, member 13 pseudogene",-,-,-,K04257//Olfactory transduction
390660,4,0,0,0,1,0,6,0,0,2,0,18,ADAMTS7P1;ADAMTS7 pseudogene 1,-,-,-,-
390667,0,0,0,0,0,0,0,0,0,0,1,0,"PTX4;pentraxin 4, long",GO:0005576//extracellular region,-,GO:0046872//metal ion binding,-
390705,0,0,0,0,0,0,0,0,2,0,13,0,"LOC390705;protein phosphatase 2, regulatory subunit B'', beta pseudogene",-,-,-,K11583//mRNA surveillance pathway;Dopaminergic synapse
390732,49,0,0,0,0,0,0,0,77,0,0,0,CES1P2;carboxylesterase 1 pseudogene 2,-,-,-,K01044//Drug metabolism - other enzymes;Metabolic pathways
390748,45,0,23,0,0,0,0,0,18,0,0,0,"PABPN1L;poly(A) binding protein, nuclear 1-like (cytoplasmic)",GO:0005737//cytoplasm,-,GO:0003723//RNA binding;GO:0000166//nucleotide binding,K14396//mRNA surveillance pathway;Influenza A
390756,0,0,0,0,0,0,0,0,3,0,0,0,"OR3A4P;olfactory receptor, family 3, subfamily A, member 4 pseudogene",-,-,-,K04257//Olfactory transduction
390790,0,0,0,0,0,0,0,0,21,0,4,0,ARL5C;ADP-ribosylation factor-like 5C,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
390792,0,0,0,0,0,0,0,0,30,0,0,0,KRT39;keratin 39,GO:0005882//intermediate filament,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
3908,0,0,0,0,0,17,84,113,103,0,5,0,"LAMA2;laminin, alpha 2",GO:0005604//basement membrane;GO:0005606//laminin-1 complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0042383//sarcolemma;GO:0043197//dendritic spine;GO:0031012//extracellular matrix,"GO:0030155//regulation of cell adhesion;GO:0045995//regulation of embryonic development;GO:0007411//axon guidance;GO:0007155//cell adhesion;GO:0007517//muscle organ development;GO:0022011//myelination in peripheral nervous system;GO:0030198//extracellular matrix organization;GO:0030334//regulation of cell migration;GO:0032224//positive regulation of synaptic transmission, cholinergic",GO:0005198//structural molecule activity;GO:0005102//receptor binding,K05637//Small cell lung cancer;Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Focal adhesion;Amoebiasis;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Toxoplasmosis;Viral myocarditis
390882,90,0,0,0,0,8,0,0,34,0,0,0,"OR7G2;olfactory receptor, family 7, subfamily G, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
390883,0,0,0,0,0,0,0,79,6,0,0,0,"OR7G3;olfactory receptor, family 7, subfamily G, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
390892,0,0,0,0,0,19,0,0,0,0,0,0,"OR7A10;olfactory receptor, family 7, subfamily A, member 10",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
3909,11,0,48,13,29,82,135,0,158,0,34,0,"LAMA3;laminin, alpha 3",GO:0005606//laminin-1 complex;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005610//laminin-5 complex,GO:0034329//cell junction assembly;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation;GO:0008544//epidermis development;GO:0045995//regulation of embryonic development;GO:0030155//regulation of cell adhesion;GO:0030334//regulation of cell migration;GO:0031581//hemidesmosome assembly;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly,GO:0005198//structural molecule activity;GO:0005102//receptor binding,K06240//ECM-receptor interaction;Pathways in cancer;Toxoplasmosis;Small cell lung cancer;Amoebiasis;Focal adhesion
390916,0,0,0,2,12,0,14,72,0,0,46,0,NUDT19;nudix (nucleoside diphosphate linked moiety X)-type motif 19,GO:0005739//mitochondrion;GO:0005777//peroxisome,GO:0008152//metabolic process,GO:0005102//receptor binding;GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K13355//Peroxisome
390927,0,133,45,48,76,74,0,198,25,0,24,0,ZNF793;zinc finger protein 793,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
390928,30,0,0,0,0,0,0,0,10,0,7,0,PAPL;iron/zinc purple acid phosphatase-like protein,GO:0005576//extracellular region,GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0003993//acid phosphatase activity,K01113//Folate biosynthesis;Aminobenzoate degradation;Microbial metabolism in diverse environments;Metabolic pathways;Two-component system;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
390940,0,0,0,0,0,0,41,0,0,0,0,0,PINLYP;phospholipase A2 inhibitor and LY6/PLAUR domain containing,GO:0005576//extracellular region,GO:0043086//negative regulation of catalytic activity,GO:0004859//phospholipase inhibitor activity,K03985//Complement and coagulation cascades
390980,0,20,0,0,3,19,9,2,60,0,19,0,ZNF805;zinc finger protein 805,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
390992,0,0,0,0,0,1,0,1,29,0,0,0,HES3;hes family bHLH transcription factor 3,GO:0005634//nucleus,"GO:0021575//hindbrain morphogenesis;GO:0021557//oculomotor nerve development;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0021558//trochlear nerve development;GO:0060164//regulation of timing of neuron differentiation;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
390999,0,0,0,0,0,0,20,0,0,0,0,0,PRAMEF12;PRAME family member 12,-,"GO:0043066//negative regulation of apoptotic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0008284//positive regulation of cell proliferation",GO:0042974//retinoic acid receptor binding,-
391,0,0,0,0,0,12,19,0,0,0,0,0,RHOG;ras homolog family member G,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion,"GO:0060326//cell chemotaxis;GO:0007266//Rho protein signal transduction;GO:1900027//regulation of ruffle assembly;GO:0016601//Rac protein signal transduction;GO:0030168//platelet activation;GO:0007264//small GTPase mediated signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032863//activation of Rac GTPase activity;GO:0008284//positive regulation of cell proliferation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007411//axon guidance;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process;GO:0007596//blood coagulation",GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07863//Salmonella infection;Bacterial invasion of epithelial cells;Shigellosis
3910,126,0,0,0,1,0,25,0,84,0,13,0,"LAMA4;laminin, alpha 4",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005606//laminin-1 complex;GO:0005605//basal lamina;GO:0005604//basement membrane;GO:0031012//extracellular matrix,GO:0030334//regulation of cell migration;GO:0001568//blood vessel development;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0050873//brown fat cell differentiation;GO:0045995//regulation of embryonic development;GO:0030155//regulation of cell adhesion,GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0005102//receptor binding,K06241//Small cell lung cancer;Amoebiasis;Focal adhesion;African trypanosomiasis;ECM-receptor interaction;Toxoplasmosis;Pathways in cancer
391003,0,0,0,0,0,0,0,0,20,0,1,0,LOC391003;PRAME family member-like,-,-,-,-
391004,0,0,0,0,0,0,0,0,14,0,0,0,PRAMEF17;PRAME family member 17,-,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0042974//retinoic acid receptor binding,-
391013,0,0,0,0,0,0,0,0,10,0,0,0,"PLA2G2C;phospholipase A2, group IIC",GO:0005576//extracellular region,GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process,GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding,K01047//Ether lipid metabolism;VEGF signaling pathway;Glycerophospholipid metabolism;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway;Vascular smooth muscle contraction;Metabolic pathways;Glutamatergic synapse;MAPK signaling pathway;Linoleic acid metabolism;alpha-Linolenic acid metabolism;Serotonergic synapse;Pancreatic secretion;GnRH signaling pathway
391037,0,0,0,0,0,0,45,0,33,0,0,0,"SKINTL;Skint-like, pseudogene",GO:0016021//integral component of membrane,-,-,-
391051,0,0,0,0,0,0,15,0,7,0,0,0,"UOX;urate oxidase, pseudogene",-,-,-,K00365//Purine metabolism;Caffeine metabolism;Microbial metabolism in diverse environments;Metabolic pathways
391059,0,0,0,0,0,0,30,0,12,0,0,0,FRRS1;ferric-chelate reductase 1,GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0000293//ferric-chelate reductase activity,K12589//RNA degradation;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K12349//Sphingolipid metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
3911,99,110,0,0,0,42,68,32,69,40,23,252,"LAMA5;laminin, alpha 5",GO:0043260//laminin-11 complex;GO:0005604//basement membrane;GO:0043259//laminin-10 complex;GO:0005615//extracellular space;GO:0005606//laminin-1 complex;GO:0005610//laminin-5 complex;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005605//basal lamina;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0001942//hair follicle development;GO:0009790//embryo development;GO:0030198//extracellular matrix organization;GO:0001525//angiogenesis;GO:0045446//endothelial cell differentiation;GO:0008283//cell proliferation;GO:0060445//branching involved in salivary gland morphogenesis;GO:0016331//morphogenesis of embryonic epithelium;GO:0007010//cytoskeleton organization;GO:0022617//extracellular matrix disassembly;GO:0042127//regulation of cell proliferation;GO:0030154//cell differentiation;GO:0016477//cell migration;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048041//focal adhesion assembly;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007229//integrin-mediated signaling pathway;GO:0030334//regulation of cell migration;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001738//morphogenesis of a polarized epithelium;GO:0045995//regulation of embryonic development;GO:0030155//regulation of cell adhesion;GO:0008037//cell recognition;GO:0030324//lung development;GO:0090002//establishment of protein localization to plasma membrane;GO:0007517//muscle organ development;GO:0042384//cilium assembly;GO:0001755//neural crest cell migration,GO:0005178//integrin binding;GO:0005198//structural molecule activity,K06240//ECM-receptor interaction;Pathways in cancer;Toxoplasmosis;Focal adhesion;Amoebiasis;Small cell lung cancer
391104,0,0,0,0,0,0,0,0,16,0,9,0,VHLL;von Hippel-Lindau tumor suppressor-like,-,-,-,K03871//Pathways in cancer;Renal cell carcinoma;Ubiquitin mediated proteolysis
391107,0,0,0,0,0,0,0,0,2,0,0,0,"OR10K2;olfactory receptor, family 10, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
391109,0,0,0,0,0,0,0,0,16,0,0,0,"OR10K1;olfactory receptor, family 10, subfamily K, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
391123,0,0,0,0,0,0,4,0,16,0,2,0,VSIG8;V-set and immunoglobulin domain containing 8,GO:0005622//intracellular;GO:0016021//integral component of membrane,-,GO:0044822//poly(A) RNA binding,K06788//Viral myocarditis
391189,0,0,0,0,0,20,0,0,0,0,0,0,"OR11L1;olfactory receptor, family 11, subfamily L, member 1",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
391190,0,0,0,0,0,0,0,0,30,0,0,0,"OR2L8;olfactory receptor, family 2, subfamily L, member 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
391191,0,0,0,0,0,0,3,0,0,0,0,0,"OR2AK2;olfactory receptor, family 2, subfamily AK, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
391194,0,0,0,0,0,0,0,0,9,0,0,0,"OR2M2;olfactory receptor, family 2, subfamily M, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
391195,66,0,0,0,0,0,0,0,11,0,0,0,"OR2T33;olfactory receptor, family 2, subfamily T, member 33",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
3912,0,100,2,9,0,57,19,0,71,153,1,1,"LAMB1;laminin, beta 1",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005607//laminin-2 complex;GO:0043257//laminin-8 complex;GO:0048471//perinuclear region of cytoplasm;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0043259//laminin-10 complex;GO:0005606//laminin-1 complex,GO:0034446//substrate adhesion-dependent cell spreading;GO:0031175//neuron projection development;GO:0042476//odontogenesis;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0007566//embryo implantation;GO:0021812//neuronal-glial interaction involved in cerebral cortex radial glia guided migration;GO:0007162//negative regulation of cell adhesion,GO:0019899//enzyme binding;GO:0043208//glycosphingolipid binding;GO:0005178//integrin binding;GO:0005201//extracellular matrix structural constituent;GO:0005198//structural molecule activity,K05636//Focal adhesion;Small cell lung cancer;Amoebiasis;Pathways in cancer;Toxoplasmosis;ECM-receptor interaction
391253,0,0,0,0,0,0,0,0,25,0,12,0,"SPINT4;serine peptidase inhibitor, Kunitz type 4",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades
391267,0,0,0,0,0,0,0,0,30,0,0,0,"ANKRD20A11P;ankyrin repeat domain 20 family, member A11, pseudogene",-,-,-,-
3913,339,0,0,0,7,10,0,0,68,0,2,1,"LAMB2;laminin, beta 2 (laminin S)",GO:0005605//basal lamina;GO:0005576//extracellular region;GO:0045202//synapse;GO:0070062//extracellular vesicular exosome;GO:0005608//laminin-3 complex;GO:0031012//extracellular matrix;GO:0043260//laminin-11 complex;GO:0005604//basement membrane,GO:0030198//extracellular matrix organization;GO:0060041//retina development in camera-type eye;GO:0007601//visual perception;GO:0048677//axon extension involved in regeneration;GO:0014002//astrocyte development;GO:0007528//neuromuscular junction development;GO:0072249//metanephric glomerular visceral epithelial cell development;GO:0072274//metanephric glomerular basement membrane development;GO:0007411//axon guidance;GO:0014044//Schwann cell development;GO:0007155//cell adhesion,GO:0005198//structural molecule activity;GO:0005178//integrin binding,K06243//ECM-receptor interaction;Toxoplasmosis;Pathways in cancer;Focal adhesion;Amoebiasis;Small cell lung cancer
391356,28,23,0,54,45,1,0,45,0,0,52,1,PTRHD1;peptidyl-tRNA hydrolase domain containing 1,GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0004045//aminoacyl-tRNA hydrolase activity,K14394//Adherens junction;Riboflavin metabolism
391365,0,0,0,0,0,31,0,0,10,0,0,0,"SULT6B1;sulfotransferase family, cytosolic, 6B, member 1",GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0008146//sulfotransferase activity,-
3914,0,0,0,0,0,34,52,14,24,0,0,78,"LAMB3;laminin, beta 3",GO:0005610//laminin-5 complex;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0031581//hemidesmosome assembly;GO:0022617//extracellular matrix disassembly;GO:0008544//epidermis development;GO:0050873//brown fat cell differentiation;GO:0034329//cell junction assembly;GO:0007155//cell adhesion;GO:0035987//endodermal cell differentiation,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0032403//protein complex binding,K06244//Focal adhesion;Small cell lung cancer;Amoebiasis;Pathways in cancer;Toxoplasmosis;ECM-receptor interaction
391475,85,0,0,0,0,0,0,54,24,0,4,0,DYTN;dystrotelin,GO:0005886//plasma membrane,-,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K10366//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Viral myocarditis;Dilated cardiomyopathy
3915,33,1,0,12,36,0,17,0,91,0,5,0,"LAMC1;laminin, gamma 1 (formerly LAMB2)",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0043260//laminin-11 complex;GO:0043259//laminin-10 complex;GO:0005606//laminin-1 complex;GO:0031012//extracellular matrix,GO:0016477//cell migration;GO:0022617//extracellular matrix disassembly;GO:0006461//protein complex assembly;GO:0031581//hemidesmosome assembly;GO:0030198//extracellular matrix organization;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007155//cell adhesion;GO:0007492//endoderm development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007411//axon guidance,GO:0043208//glycosphingolipid binding;GO:0005201//extracellular matrix structural constituent,K05635//ECM-receptor interaction;Toxoplasmosis;Pathways in cancer;Prion diseases;Focal adhesion;Amoebiasis;Small cell lung cancer
391518,0,0,0,0,0,0,14,0,0,0,0,0,VENTXP7;VENT homeobox pseudogene 7,-,-,-,K09341//HTLV-I infection
3916,1,1,0,0,3,10,21,39,20,0,0,0,LAMP1;lysosomal-associated membrane protein 1,GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0005771//multivesicular body;GO:0042383//sarcolemma;GO:0097208//alveolar lamellar body;GO:0043025//neuronal cell body;GO:0044194//cytolytic granule;GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0042470//melanosome;GO:0010008//endosome membrane;GO:0005770//late endosome;GO:0016020//membrane,GO:0043323//positive regulation of natural killer cell degranulation;GO:0090160//Golgi to lysosome transport;GO:1902513//regulation of organelle transport along microtubule;GO:0050821//protein stabilization;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0006914//autophagy;GO:0072594//establishment of protein localization to organelle;GO:0048102//autophagic cell death;GO:0008626//granzyme-mediated apoptotic signaling pathway,GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding,K06528//Phagosome;Tuberculosis;Lysosome
391622,0,0,0,0,0,1,34,0,29,0,0,0,"USP17L6P;ubiquitin specific peptidase 17-like family member 6, pseudogene",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity;GO:0008234//cysteine-type peptidase activity,-
391712,1,0,0,0,0,0,28,0,17,0,0,0,TRIM61;tripartite motif containing 61,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
3918,63,0,0,0,0,22,70,0,20,99,0,0,"LAMC2;laminin, gamma 2",GO:0005576//extracellular region;GO:0005607//laminin-2 complex;GO:0005615//extracellular space;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005938//cell cortex;GO:0005610//laminin-5 complex,GO:0034329//cell junction assembly;GO:0007155//cell adhesion;GO:0008544//epidermis development;GO:0031581//hemidesmosome assembly;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly,GO:0008201//heparin binding,K06246//Focal adhesion;Small cell lung cancer;Amoebiasis;Pathways in cancer;Toxoplasmosis;ECM-receptor interaction
392,65,1,1,26,13,4,19,69,63,142,0,0,ARHGAP1;Rho GTPase activating protein 1,GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007264//small GTPase mediated signal transduction;GO:0032855//positive regulation of Rac GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0009967//positive regulation of signal transduction;GO:0007266//Rho protein signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005100//Rho GTPase activator activity;GO:0005515//protein binding;GO:0030675//Rac GTPase activator activity;GO:0017124//SH3 domain binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
3920,0,0,0,4,58,19,35,0,46,0,0,0,LAMP2;lysosomal-associated membrane protein 2,GO:0031088//platelet dense granule membrane;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0031902//late endosome membrane;GO:0005764//lysosome,GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0050821//protein stabilization;GO:0030168//platelet activation,GO:0019904//protein domain specific binding;GO:0019899//enzyme binding,K06528//Tuberculosis;Lysosome;Phagosome
3921,0,186,6,132,359,0,2,2,9,0,1,0,RPSA;ribosomal protein SA,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030686//90S preribosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus,"GO:0006407//rRNA export from nucleus;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0007155//cell adhesion;GO:0044267//cellular protein metabolic process;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0006412//translation;GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0010467//gene expression;GO:0000028//ribosomal small subunit assembly;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0043022//ribosome binding;GO:0043236//laminin binding;GO:0005055//laminin receptor activity;GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02998//Ribosome
392188,1,0,0,0,0,0,0,0,6,0,0,0,USP17L8;ubiquitin specific peptidase 17-like family member 8,GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity,-
392197,0,0,0,0,0,0,14,0,0,0,0,0,USP17L7;ubiquitin specific peptidase 17-like family member 7,GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity,-
392232,4,0,0,0,0,10,0,7,17,0,21,0,"LOC392232;transient receptor potential cation channel, subfamily A, member 1 pseudogene",-,-,-,-
392255,83,0,0,0,0,0,0,0,23,0,0,0,GDF6;growth differentiation factor 6,GO:0005615//extracellular space,"GO:1990009//retinal cell apoptotic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0006915//apoptotic process;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0030509//BMP signaling pathway;GO:0040007//growth",GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity;GO:0008083//growth factor activity,K04664//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
392307,53,0,0,0,0,0,17,0,17,0,27,0,"FAM221B;family with sequence similarity 221, member B",-,-,-,-
392309,0,0,0,0,0,0,0,121,0,0,0,0,"OR13J1;olfactory receptor, family 13, subfamily J, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
392360,0,0,0,0,0,35,0,0,12,0,0,0,"CTSL3P;cathepsin L family member 3, pseudogene",-,GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity,K01365//Antigen processing and presentation;Lysosome;Phagosome;Rheumatoid arthritis
392376,0,0,0,0,0,0,0,0,0,0,13,0,"OR13C2;olfactory receptor, family 13, subfamily C, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
392391,0,0,0,0,0,0,0,0,19,0,0,0,"OR5C1;olfactory receptor, family 5, subfamily C, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
392392,0,0,0,0,0,3,2,0,17,0,0,0,"OR1K1;olfactory receptor, family 1, subfamily K, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
392399,0,0,0,0,0,0,0,0,17,0,0,0,LCN9;lipocalin 9,GO:0005576//extracellular region,GO:0006810//transport,GO:0005215//transporter activity;GO:0005550//pheromone binding,-
392452,0,0,0,0,0,0,0,68,0,0,0,0,LOC392452;mitochondrial fission factor pseudogene,-,-,-,-
392465,0,0,0,0,0,32,0,0,10,0,0,0,GLOD5;glyoxalase domain containing 5,-,-,-,-
392490,0,0,0,0,0,15,0,0,18,0,16,0,FLJ44635;TPT1-like protein,GO:0070062//extracellular vesicular exosome,-,-,-
3925,1,16,0,3,5,2,0,0,27,0,0,0,STMN1;stathmin 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005874//microtubule,GO:0009615//response to virus;GO:0007052//mitotic spindle organization;GO:0051272//positive regulation of cellular component movement;GO:0031115//negative regulation of microtubule polymerization;GO:0035556//intracellular signal transduction;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0007019//microtubule depolymerization,GO:0004871//signal transducer activity;GO:0015631//tubulin binding,K04381//MAPK signaling pathway
392509,0,0,16,0,20,0,27,0,5,0,22,0,ARL13A;ADP-ribosylation factor-like 13A,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
392617,0,0,0,0,0,0,0,0,2,1,0,338,ELFN1;extracellular leucine-rich repeat and fibronectin type III domain containing 1,GO:0016021//integral component of membrane;GO:0060076//excitatory synapse;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite,GO:0050808//synapse organization;GO:0010923//negative regulation of phosphatase activity,GO:0004864//protein phosphatase inhibitor activity;GO:0019902//phosphatase binding,K06838//Axon guidance
392636,0,0,0,0,0,13,14,0,26,0,2,0,AGMO;alkylglycerol monooxygenase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0046485//ether lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process;GO:0006643//membrane lipid metabolic process,GO:0005506//iron ion binding;GO:0050479//glyceryl-ether monooxygenase activity,-
3927,0,19,1,6,54,26,0,0,48,0,0,0,LASP1;LIM and SH3 protein 1,GO:0030864//cortical actin cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,GO:0009967//positive regulation of signal transduction;GO:0034220//ion transmembrane transport;GO:0006811//ion transport,GO:0005070//SH3/SH2 adaptor activity;GO:0015075//ion transmembrane transporter activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0051015//actin filament binding,K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
392862,103,34,0,11,35,0,18,120,29,0,60,0,"GRID2IP;glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein",GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0060292//long term synaptic depression,-,K04512//Wnt signaling pathway
3929,0,0,0,0,0,17,0,0,18,35,18,0,LBP;lipopolysaccharide binding protein,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0009986//cell surface,GO:0002232//leukocyte chemotaxis involved in inflammatory response;GO:0002281//macrophage activation involved in immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0032490//detection of molecule of bacterial origin;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0006953//acute-phase response;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0071223//cellular response to lipoteichoic acid;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0043032//positive regulation of macrophage activation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0050829//defense response to Gram-negative bacterium;GO:0015920//lipopolysaccharide transport;GO:0032722//positive regulation of chemokine production;GO:0045087//innate immune response;GO:0044130//negative regulation of growth of symbiont in host;GO:0008228//opsonization;GO:0032757//positive regulation of interleukin-8 production;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006968//cellular defense response;GO:0071222//cellular response to lipopolysaccharide;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0050830//defense response to Gram-positive bacterium;GO:0090023//positive regulation of neutrophil chemotaxis,GO:0070891//lipoteichoic acid binding;GO:0005515//protein binding;GO:0001530//lipopolysaccharide binding;GO:0005102//receptor binding,K05399//Tuberculosis;Toll-like receptor signaling pathway;NF-kappa B signaling pathway;Salmonella infection
393,81,0,0,0,0,16,52,0,56,0,15,0,ARHGAP4;Rho GTPase activating protein 4,GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0005829//cytosol,GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0010764//negative regulation of fibroblast migration;GO:0007010//cytoskeleton organization;GO:0007266//Rho protein signal transduction;GO:0009967//positive regulation of signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0030517//negative regulation of axon extension;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity,K07526//Axon guidance
3930,0,0,0,11,0,0,0,0,0,1,17,1,LBR;lamin B receptor,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005639//integral component of nuclear inner membrane;GO:0005635//nuclear envelope;GO:0031965//nuclear membrane,GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process,"GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0070087//chromo shadow domain binding;GO:0005521//lamin binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding",K00222//Steroid biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites
393046,0,0,0,0,0,0,19,0,33,0,0,0,"OR2A5;olfactory receptor, family 2, subfamily A, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
3931,0,0,0,0,0,0,0,0,8,0,16,0,LCAT;lecithin-cholesterol acyltransferase,GO:0034364//high-density lipoprotein particle;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0042158//lipoprotein biosynthetic process;GO:0034435//cholesterol esterification;GO:0006644//phospholipid metabolic process;GO:0042157//lipoprotein metabolic process;GO:0034375//high-density lipoprotein particle remodeling;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0044281//small molecule metabolic process;GO:0030301//cholesterol transport;GO:0090107//regulation of high-density lipoprotein particle assembly;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0006656//phosphatidylcholine biosynthetic process;GO:0008203//cholesterol metabolic process,GO:0034186//apolipoprotein A-I binding;GO:0005515//protein binding;GO:0004607//phosphatidylcholine-sterol O-acyltransferase activity,K00650//Glycerophospholipid metabolism;Tyrosine metabolism
3932,0,0,50,0,0,0,41,0,51,0,0,0,"LCK;LCK proto-oncogene, Src family tyrosine kinase",GO:0005911//cell-cell junction;GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0001772//immunological synapse;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0000242//pericentriolar material,GO:0016311//dephosphorylation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0031295//T cell costimulation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042493//response to drug;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0030217//T cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050900//leukocyte migration;GO:0006882//cellular zinc ion homeostasis;GO:0046777//protein autophosphorylation;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0051209//release of sequestered calcium ion into cytosol;GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0010628//positive regulation of gene expression;GO:0048015//phosphatidylinositol-mediated signaling;GO:0042542//response to hydrogen peroxide;GO:0045087//innate immune response;GO:0050870//positive regulation of T cell activation;GO:0030097//hemopoiesis;GO:0007596//blood coagulation;GO:0050690//regulation of defense response to virus by virus;GO:0050852//T cell receptor signaling pathway;GO:0010043//response to zinc ion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016032//viral process;GO:0007568//aging;GO:0030168//platelet activation,GO:0001948//glycoprotein binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0051117//ATPase binding;GO:0004713//protein tyrosine kinase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0042609//CD4 receptor binding;GO:0003823//antigen binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0019903//protein phosphatase binding;GO:0032403//protein complex binding;GO:0042610//CD8 receptor binding;GO:0042169//SH2 domain binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0043548//phosphatidylinositol 3-kinase binding,K05856//HTLV-I infection;NF-kappa B signaling pathway;Natural killer cell mediated cytotoxicity;Primary immunodeficiency;T cell receptor signaling pathway;Osteoclast differentiation
3934,0,0,0,0,0,52,0,0,10,0,4,0,LCN2;lipocalin 2,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0045087//innate immune response;GO:0015891//siderophore transport;GO:0006915//apoptotic process;GO:0006811//ion transport;GO:0055072//iron ion homeostasis,GO:0036094//small molecule binding;GO:0005215//transporter activity;GO:0005506//iron ion binding,K01830//Arachidonic acid metabolism;Metabolic pathways;K03999//Amoebiasis;Complement and coagulation cascades;Systemic lupus erythematosus;Prion diseases
3936,0,131,4,133,499,0,17,0,29,0,0,0,LCP1;lymphocyte cytosolic protein 1 (L-plastin),GO:0032432//actin filament bundle;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0001891//phagocytic cup;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005615//extracellular space;GO:0005925//focal adhesion,"GO:0044319//wound healing, spreading of cells;GO:0010737//protein kinase A signaling;GO:0051017//actin filament bundle assembly;GO:0002286//T cell activation involved in immune response;GO:0033157//regulation of intracellular protein transport;GO:0031100//organ regeneration;GO:0016477//cell migration",GO:0005509//calcium ion binding;GO:0051015//actin filament binding;GO:0042802//identical protein binding;GO:0003779//actin binding,-
3937,66,0,0,0,0,0,0,0,20,0,0,0,LCP2;lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa),GO:0005829//cytosol;GO:0005911//cell-cell junction,GO:0045087//innate immune response;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0045576//mast cell activation;GO:0006955//immune response;GO:0050852//T cell receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050663//cytokine secretion;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0005515//protein binding,K07361//T cell receptor signaling pathway;Osteoclast differentiation;Natural killer cell mediated cytotoxicity;Fc epsilon RI signaling pathway
3938,0,0,0,0,0,107,16,49,46,0,0,25,LCT;lactase,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044245//polysaccharide digestion,GO:0000016//lactase activity;GO:0017042//glycosylceramidase activity,K01229//Metabolic pathways;Galactose metabolism;Carbohydrate digestion and absorption
3939,0,124,1,38,182,13,19,12,25,0,0,0,LDHA;lactate dehydrogenase A,GO:0070062//extracellular vesicular exosome;GO:0035686//sperm fibrous sheath;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005634//nucleus,GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0055114//oxidation-reduction process;GO:0044262//cellular carbohydrate metabolic process;GO:0031668//cellular response to extracellular stimulus,GO:0004459//L-lactate dehydrogenase activity;GO:0005515//protein binding,K00016//Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Propanoate metabolism;Microbial metabolism in diverse environments;Pyruvate metabolism;Metabolic pathways
394,0,9,3,101,346,28,25,89,47,0,10,350,ARHGAP5;Rho GTPase activating protein 5,GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity;GO:0008361//regulation of cell size;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0006184//GTP catabolic process;GO:0007155//cell adhesion;GO:0030879//mammary gland development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0030335//positive regulation of cell migration,GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0042169//SH2 domain binding,K13709//Focal adhesion;Leukocyte transendothelial migration
394263,0,0,0,0,0,0,0,0,5,0,4,0,"MUC21;mucin 21, cell surface associated",GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0022408//negative regulation of cell-cell adhesion;GO:0010812//negative regulation of cell-substrate adhesion,-,-
3945,0,3,1,30,145,14,30,0,31,0,0,0,LDHB;lactate dehydrogenase B,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006089//lactate metabolic process;GO:0019674//NAD metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0006096//glycolytic process;GO:0006090//pyruvate metabolic process;GO:0044237//cellular metabolic process,GO:0019900//kinase binding;GO:0051287//NAD binding;GO:0005515//protein binding;GO:0004459//L-lactate dehydrogenase activity;GO:0042802//identical protein binding,K00016//Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Cysteine and methionine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Pyruvate metabolism;Propanoate metabolism
3948,0,1,0,7,1,0,2,0,0,0,0,0,LDHC;lactate dehydrogenase C,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0031514//motile cilium,GO:0019244//lactate biosynthetic process from pyruvate;GO:0030317//sperm motility;GO:0006096//glycolytic process;GO:0019516//lactate oxidation;GO:0044262//cellular carbohydrate metabolic process;GO:0006754//ATP biosynthetic process,GO:0004459//L-lactate dehydrogenase activity,K00016//Pyruvate metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Metabolic pathways;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis
3949,85,8,0,0,18,0,17,0,39,0,0,0,LDLR;low density lipoprotein receptor,GO:0005905//coated pit;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0009897//external side of plasma membrane;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0034362//low-density lipoprotein particle,"GO:0042632//cholesterol homeostasis;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0034383//low-density lipoprotein particle clearance;GO:0030299//intestinal cholesterol absorption;GO:0015914//phospholipid transport;GO:0016032//viral process;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0042157//lipoprotein metabolic process;GO:2000188//regulation of cholesterol homeostasis;GO:0070508//cholesterol import;GO:0030301//cholesterol transport;GO:0007603//phototransduction, visible light;GO:0008203//cholesterol metabolic process;GO:0042159//lipoprotein catabolic process;GO:0006629//lipid metabolic process;GO:0001523//retinoid metabolic process;GO:0044281//small molecule metabolic process",GO:0005041//low-density lipoprotein receptor activity;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0030169//low-density lipoprotein particle binding;GO:0005515//protein binding;GO:0001948//glycoprotein binding,K12473//Toxoplasmosis;Endocytosis;Hepatitis C;Bile secretion
395,95,99,0,26,80,20,32,62,0,0,5,0,ARHGAP6;Rho GTPase activating protein 6,GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005884//actin filament,GO:0048041//focal adhesion assembly;GO:0051497//negative regulation of stress fiber assembly;GO:0007264//small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051895//negative regulation of focal adhesion assembly;GO:0007266//Rho protein signal transduction;GO:0009967//positive regulation of signal transduction;GO:0043087//regulation of GTPase activity;GO:0010518//positive regulation of phospholipase activity;GO:0030041//actin filament polymerization;GO:0007202//activation of phospholipase C activity,GO:0017124//SH3 domain binding;GO:0005100//Rho GTPase activator activity;GO:0043274//phospholipase binding;GO:0016004//phospholipase activator activity;GO:0005070//SH3/SH2 adaptor activity,K07526//Axon guidance
3950,0,0,0,0,0,0,0,0,19,0,0,0,LECT2;leukocyte cell-derived chemotaxin 2,GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0006935//chemotaxis;GO:0001501//skeletal system development;GO:0030178//negative regulation of Wnt signaling pathway,GO:0042802//identical protein binding,-
3952,100,0,0,0,0,1,1,41,11,0,13,0,LEP;leptin,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0033686//positive regulation of luteinizing hormone secretion;GO:0006112//energy reserve metabolic process;GO:0071300//cellular response to retinoic acid;GO:0042755//eating behavior;GO:0007623//circadian rhythm;GO:0030073//insulin secretion;GO:0050810//regulation of steroid biosynthetic process;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0042445//hormone metabolic process;GO:0033210//leptin-mediated signaling pathway;GO:0060587//regulation of lipoprotein lipid oxidation;GO:0001542//ovulation from ovarian follicle;GO:0006635//fatty acid beta-oxidation;GO:0033197//response to vitamin E;GO:0008343//adult feeding behavior;GO:0045598//regulation of fat cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0001890//placenta development;GO:0043410//positive regulation of MAPK cascade;GO:0030300//regulation of intestinal cholesterol absorption;GO:0050901//leukocyte tethering or rolling;GO:0008284//positive regulation of cell proliferation;GO:0070093//negative regulation of glucagon secretion;GO:0042593//glucose homeostasis;GO:0007565//female pregnancy;GO:0071298//cellular response to L-ascorbic acid;GO:0008217//regulation of blood pressure;GO:0001666//response to hypoxia;GO:0006114//glycerol biosynthetic process;GO:0002021//response to dietary excess;GO:0045639//positive regulation of myeloid cell differentiation;GO:0046881//positive regulation of follicle-stimulating hormone secretion;GO:0035630//bone mineralization involved in bone maturation;GO:2000491//positive regulation of hepatic stellate cell activation;GO:0021954//central nervous system neuron development;GO:0006006//glucose metabolic process;GO:0050796//regulation of insulin secretion;GO:0043270//positive regulation of ion transport;GO:0032099//negative regulation of appetite;GO:0001819//positive regulation of cytokine production;GO:0008203//cholesterol metabolic process;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0061037//negative regulation of cartilage development;GO:0060612//adipose tissue development;GO:0008206//bile acid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000486//negative regulation of glutamine transport;GO:0007260//tyrosine phosphorylation of STAT protein;GO:2000366//positive regulation of STAT protein import into nucleus;GO:0006111//regulation of gluconeogenesis;GO:0045906//negative regulation of vasoconstriction;GO:0032868//response to insulin;GO:0048639//positive regulation of developmental growth,GO:0051428//peptide hormone receptor binding;GO:0005179//hormone activity;GO:0008083//growth factor activity,K05424//Neuroactive ligand-receptor interaction;Adipocytokine signaling pathway;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3953,0,0,0,0,0,23,37,0,7,0,9,0,LEPR;leptin receptor,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex,GO:0006112//energy reserve metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0045721//negative regulation of gluconeogenesis;GO:0051346//negative regulation of hydrolase activity;GO:0008203//cholesterol metabolic process;GO:0007275//multicellular organismal development;GO:0019221//cytokine-mediated signaling pathway,GO:0004896//cytokine receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding,K05062//Adipocytokine signaling pathway;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;Neuroactive ligand-receptor interaction
3954,0,0,0,1,21,10,38,0,0,0,27,0,LETM1;leucine zipper-EF-hand containing transmembrane protein 1,GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0042407//cristae formation,GO:0005515//protein binding;GO:0005509//calcium ion binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
3955,87,0,0,0,0,0,0,0,11,0,1,0,LFNG;LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,GO:0031982//vesicle;GO:0030173//integral component of Golgi membrane;GO:0005576//extracellular region,GO:0045747//positive regulation of Notch signaling pathway;GO:0008593//regulation of Notch signaling pathway;GO:0008152//metabolic process;GO:0009887//organ morphogenesis;GO:0007143//female meiotic division;GO:0032092//positive regulation of protein binding;GO:0001541//ovarian follicle development;GO:0014807//regulation of somitogenesis;GO:0001756//somitogenesis;GO:0007386//compartment pattern specification;GO:0007219//Notch signaling pathway,GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding,K05948//Other types of O-glycan biosynthesis;Notch signaling pathway
3956,0,0,0,0,0,8,0,0,0,0,0,0,"LGALS1;lectin, galactoside-binding, soluble, 1",GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005622//intracellular;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0031012//extracellular matrix,GO:0042493//response to drug;GO:0042981//regulation of apoptotic process;GO:0031295//T cell costimulation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0034120//positive regulation of erythrocyte aggregation;GO:0010977//negative regulation of neuron projection development;GO:0007165//signal transduction;GO:0045445//myoblast differentiation;GO:0002317//plasma cell differentiation;GO:0006915//apoptotic process;GO:0048678//response to axon injury;GO:0033555//multicellular organismal response to stress;GO:0071333//cellular response to glucose stimulus;GO:0010812//negative regulation of cell-substrate adhesion;GO:0071407//cellular response to organic cyclic compound,GO:0004871//signal transducer activity;GO:0016936//galactoside binding;GO:0001948//glycoprotein binding;GO:0043236//laminin binding;GO:0005515//protein binding;GO:0030395//lactose binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity,-
3957,0,21,0,0,7,9,0,0,0,0,0,0,"LGALS2;lectin, galactoside-binding, soluble, 2",-,-,GO:0016936//galactoside binding;GO:0030246//carbohydrate binding,-
3958,0,4,0,21,219,0,0,0,19,0,3,314,"LGALS3;lectin, galactoside-binding, soluble, 3",GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005743//mitochondrial inner membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005681//spliceosomal complex;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0030593//neutrophil chemotaxis;GO:0070232//regulation of T cell apoptotic process;GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0071677//positive regulation of mononuclear cell migration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0050918//positive chemotaxis;GO:0045087//innate immune response;GO:0042129//regulation of T cell proliferation;GO:0030198//extracellular matrix organization;GO:0071674//mononuclear cell migration;GO:0030855//epithelial cell differentiation;GO:0002548//monocyte chemotaxis;GO:0048246//macrophage chemotaxis;GO:2001189//negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell;GO:2000521//negative regulation of immunological synapse formation;GO:0090280//positive regulation of calcium ion import;GO:0001501//skeletal system development;GO:0045806//negative regulation of endocytosis;GO:0048245//eosinophil chemotaxis,GO:0043236//laminin binding;GO:0019863//IgE binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030246//carbohydrate binding;GO:0042056//chemoattractant activity,-
3959,0,0,0,0,0,0,29,3,0,0,16,0,"LGALS3BP;lectin, galactoside-binding, soluble, 3 binding protein",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0016020//membrane;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis;GO:0006968//cellular defense response,GO:0005044//scavenger receptor activity,K13912//Salivary secretion
3960,0,0,0,0,0,0,13,0,0,0,0,0,"LGALS4;lectin, galactoside-binding, soluble, 4",GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
3964,0,41,49,132,286,22,14,60,124,162,84,0,"LGALS8;lectin, galactoside-binding, soluble, 8",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0031295//T cell costimulation;GO:0002317//plasma cell differentiation,GO:0005515//protein binding;GO:0030246//carbohydrate binding,-
3965,0,0,0,0,0,0,9,0,54,0,4,0,"LGALS9;lectin, galactoside-binding, soluble, 9",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0030246//carbohydrate binding;GO:0004871//signal transducer activity;GO:0005534//galactose binding,-
397,0,0,0,0,0,0,0,0,20,124,0,0,ARHGDIB;Rho GDP dissociation inhibitor (GDI) beta,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0006955//immune response;GO:0030036//actin cytoskeleton organization;GO:0007162//negative regulation of cell adhesion;GO:0006928//cellular component movement;GO:0007275//multicellular organismal development;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity,GO:0005094//Rho GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity,K12462//Vasopressin-regulated water reabsorption;Neurotrophin signaling pathway
3972,0,0,0,0,7,0,0,0,20,0,0,0,LHB;luteinizing hormone beta polypeptide,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0016486//peptide hormone processing;GO:0006701//progesterone biosynthetic process;GO:0007267//cell-cell signaling;GO:0044267//cellular protein metabolic process;GO:0008584//male gonad development;GO:0007165//signal transduction,GO:0005102//receptor binding;GO:0005179//hormone activity,K08521//Neuroactive ligand-receptor interaction;GnRH signaling pathway
3973,4,0,0,0,0,27,61,0,8,0,0,0,LHCGR;luteinizing hormone/choriogonadotropin receptor,GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0043950//positive regulation of cAMP-mediated signaling;GO:0060065//uterus development;GO:0046544//development of secondary male sexual characteristics;GO:0042700//luteinizing hormone signaling pathway;GO:0030539//male genitalia development;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0007190//activation of adenylate cyclase activity;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0072520//seminiferous tubule development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090030//regulation of steroid hormone biosynthetic process;GO:0071371//cellular response to gonadotropin stimulus;GO:0001541//ovarian follicle development;GO:0050890//cognition;GO:0007283//spermatogenesis;GO:0008584//male gonad development",GO:0035472//choriogonadotropin hormone receptor activity;GO:0038106//choriogonadotropin hormone binding;GO:0004964//luteinizing hormone receptor activity,K04248//Neuroactive ligand-receptor interaction;Calcium signaling pathway
3975,64,0,0,0,0,0,1,0,0,125,5,0,LHX1;LIM homeobox 1,GO:0005634//nucleus;GO:0043234//protein complex,"GO:0060068//vagina development;GO:0021549//cerebellum development;GO:0060065//uterus development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0090009//primitive streak formation;GO:0060322//head development;GO:0009653//anatomical structure morphogenesis;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0001706//endoderm formation;GO:0007389//pattern specification process;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0072224//metanephric glomerulus development;GO:0009880//embryonic pattern specification;GO:0001705//ectoderm formation;GO:0021517//ventral spinal cord development;GO:2000744//positive regulation of anterior head development;GO:0097477//lateral motor column neuron migration;GO:0072177//mesonephric duct development;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0001657//ureteric bud development;GO:0001655//urogenital system development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0035852//horizontal cell localization;GO:0006366//transcription from RNA polymerase II promoter;GO:0010842//retina layer formation;GO:0010468//regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0007399//nervous system development;GO:0072284//metanephric S-shaped body morphogenesis;GO:0035849//nephric duct elongation;GO:0021527//spinal cord association neuron differentiation;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0032525//somite rostral/caudal axis specification;GO:0001822//kidney development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0008045//motor neuron axon guidance;GO:0048703//embryonic viscerocranium morphogenesis;GO:0009887//organ morphogenesis;GO:0021871//forebrain regionalization;GO:0035846//oviduct epithelium development;GO:0009952//anterior/posterior pattern specification;GO:0060067//cervix development;GO:0035847//uterine epithelium development;GO:0001702//gastrulation with mouth forming second;GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0009948//anterior/posterior axis specification;GO:0009791//post-embryonic development;GO:2000543//positive regulation of gastrulation;GO:0060066//oviduct development;GO:0021537//telencephalon development;GO:0061205//paramesonephric duct development;GO:0035502//metanephric part of ureteric bud development;GO:0072283//metanephric renal vesicle morphogenesis;GO:0040019//positive regulation of embryonic development;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0060429//epithelium development;GO:0048793//pronephros development",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003714//transcription corepressor activity,-
3976,0,0,0,0,0,0,0,0,7,60,15,0,LIF;leukemia inhibitory factor,GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006955//immune response;GO:0008285//negative regulation of cell proliferation;GO:1900182//positive regulation of protein localization to nucleus;GO:0007566//embryo implantation;GO:0060707//trophoblast giant cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0008284//positive regulation of cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0048666//neuron development;GO:0045835//negative regulation of meiosis;GO:0019827//stem cell maintenance;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0060426//lung vasculature development;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0060463//lung lobe morphogenesis;GO:0060708//spongiotrophoblast differentiation;GO:0048644//muscle organ morphogenesis;GO:1901676//positive regulation of histone H3-K27 acetylation;GO:0001974//blood vessel remodeling;GO:0048286//lung alveolus development;GO:0045651//positive regulation of macrophage differentiation;GO:0046888//negative regulation of hormone secretion;GO:0006366//transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0046697//decidualization;GO:0048711//positive regulation of astrocyte differentiation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005125//cytokine activity;GO:0005146//leukemia inhibitory factor receptor binding;GO:0008083//growth factor activity;GO:0001135//RNA polymerase II transcription factor recruiting transcription factor activity;GO:0005102//receptor binding,K05419//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3977,80,83,0,103,108,47,0,0,93,0,0,0,LIFR;leukemia inhibitory factor receptor alpha,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0038165//oncostatin-M-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0048861//leukemia inhibitory factor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0070120//ciliary neurotrophic factor-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0034097//response to cytokine,GO:0004923//leukemia inhibitory factor receptor activity;GO:0004897//ciliary neurotrophic factor receptor activity;GO:0004924//oncostatin-M receptor activity;GO:0019838//growth factor binding;GO:0005127//ciliary neurotrophic factor receptor binding,K05058//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
3978,0,0,0,0,0,0,41,0,16,0,0,0,"LIG1;ligase I, DNA, ATP-dependent",GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0009653//anatomical structure morphogenesis;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0042542//response to hydrogen peroxide;GO:0051301//cell division;GO:0051103//DNA ligation involved in DNA repair;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000724//double-strand break repair via homologous recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0000278//mitotic cell cycle;GO:0033151//V(D)J recombination;GO:0006284//base-excision repair;GO:0006273//lagging strand elongation;GO:0071897//DNA biosynthetic process;GO:0006302//double-strand break repair;GO:0006259//DNA metabolic process;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication",GO:0005524//ATP binding;GO:0003910//DNA ligase (ATP) activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K10747//Nucleotide excision repair;DNA replication;Mismatch repair;Base excision repair
398,0,0,0,0,0,0,0,0,18,0,10,0,ARHGDIG;Rho GDP dissociation inhibitor (GDI) gamma,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005829//cytosol;GO:0016020//membrane,GO:0007266//Rho protein signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032880//regulation of protein localization;GO:0007264//small GTPase mediated signal transduction;GO:0007162//negative regulation of cell adhesion,GO:0005096//GTPase activator activity;GO:0005094//Rho GDP-dissociation inhibitor activity,K12462//Neurotrophin signaling pathway;Vasopressin-regulated water reabsorption
3980,46,45,0,20,52,34,0,42,16,160,0,1,"LIG3;ligase III, DNA, ATP-dependent",GO:0005694//chromosome;GO:0005739//mitochondrion;GO:0000795//synaptonemal complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006289//nucleotide-excision repair;GO:0006281//DNA repair;GO:0006288//base-excision repair, DNA ligation;GO:0006273//lagging strand elongation;GO:0045910//negative regulation of DNA recombination;GO:0033151//V(D)J recombination;GO:0006284//base-excision repair;GO:0043504//mitochondrial DNA repair;GO:0071897//DNA biosynthetic process",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003910//DNA ligase (ATP) activity;GO:0005524//ATP binding,K10776//Base excision repair
3981,0,26,0,7,21,0,19,2,27,0,0,0,"LIG4;ligase IV, DNA, ATP-dependent",GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0032807//DNA ligase IV complex;GO:0005634//nucleus;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0005886//plasma membrane;GO:0000793//condensed chromosome;GO:0070419//nonhomologous end joining complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0035019//somatic stem cell maintenance;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0050769//positive regulation of neurogenesis;GO:0006273//lagging strand elongation;GO:0033151//V(D)J recombination;GO:0016032//viral process;GO:0043524//negative regulation of neuron apoptotic process;GO:0071897//DNA biosynthetic process;GO:0033077//T cell differentiation in thymus;GO:0000012//single strand break repair;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0010165//response to X-ray;GO:0051276//chromosome organization;GO:0002328//pro-B cell differentiation;GO:0007049//cell cycle;GO:0051103//DNA ligation involved in DNA repair;GO:0075713//establishment of integrated proviral latency;GO:0045190//isotype switching;GO:0033153//T cell receptor V(D)J recombination;GO:0051102//DNA ligation involved in DNA recombination;GO:0001701//in utero embryonic development;GO:0051301//cell division;GO:0007417//central nervous system development;GO:0048146//positive regulation of fibroblast proliferation;GO:0010332//response to gamma radiation;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006266//DNA ligation;GO:0008283//cell proliferation;GO:0051402//neuron apoptotic process",GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0003910//DNA ligase (ATP) activity;GO:0016874//ligase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,K10777//Non-homologous end-joining
3982,0,0,0,0,0,0,0,0,0,209,3,0,"LIM2;lens intrinsic membrane protein 2, 19kDa",GO:0031982//vesicle;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0002088//lens development in camera-type eye;GO:0007043//cell-cell junction assembly,GO:0005212//structural constituent of eye lens,K10136//p53 signaling pathway;K06087//Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Cell adhesion molecules (CAMs);Tight junction;Hepatitis C
3983,0,1,1,16,72,43,68,0,59,0,32,0,ABLIM1;actin binding LIM protein 1,GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0015629//actin cytoskeleton,GO:0007411//axon guidance;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0030032//lamellipodium assembly;GO:0007010//cytoskeleton organization;GO:0009887//organ morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003779//actin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K07520//Axon guidance
3984,0,1,0,0,0,0,0,88,28,0,0,0,LIMK1;LIM domain kinase 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0043005//neuron projection;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0051496//positive regulation of stress fiber assembly;GO:0007165//signal transduction;GO:0007266//Rho protein signal transduction;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030036//actin cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0032233//positive regulation of actin filament bundle assembly;GO:0045773//positive regulation of axon extension;GO:0007411//axon guidance;GO:0051444//negative regulation of ubiquitin-protein transferase activity,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0031072//heat shock protein binding;GO:0008270//zinc ion binding,K05743//Fc gamma R-mediated phagocytosis;Regulation of actin cytoskeleton;Axon guidance
3985,0,1,17,2,31,1,0,0,75,0,0,0,LIMK2;LIM domain kinase 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005801//cis-Golgi network,GO:0016310//phosphorylation;GO:0007283//spermatogenesis;GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0008270//zinc ion binding;GO:0005524//ATP binding,K05744//Axon guidance;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis
3987,14,0,0,0,24,0,58,0,0,0,0,0,LIMS1;LIM and senescent cell antigen-like domains 1,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0048471//perinuclear region of cytoplasm,"GO:2000346//negative regulation of hepatocyte proliferation;GO:0007163//establishment or maintenance of cell polarity;GO:0034329//cell junction assembly;GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0051291//protein heterooligomerization;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0007160//cell-matrix adhesion;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0007569//cell aging;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045216//cell-cell junction organization;GO:0043009//chordate embryonic development",GO:0008270//zinc ion binding;GO:0005515//protein binding,K05760//Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Chemokine signaling pathway;VEGF signaling pathway;Leukocyte transendothelial migration;Focal adhesion
3988,0,0,0,4,15,0,0,0,10,0,0,298,"LIPA;lipase A, lysosomal acid, cholesterol esterase",GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome,GO:0048771//tissue remodeling;GO:0006954//inflammatory response;GO:0048873//homeostasis of number of cells within a tissue;GO:0016042//lipid catabolic process;GO:0001816//cytokine production;GO:0030324//lung development;GO:0000902//cell morphogenesis;GO:0008283//cell proliferation,GO:0016298//lipase activity;GO:0004771//sterol esterase activity,K01052//Steroid biosynthesis;Lysosome
399,0,0,0,0,0,9,0,0,40,0,0,0,RHOH;ras homolog family member H,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0001772//immunological synapse;GO:0005737//cytoplasm,"GO:0045576//mast cell activation;GO:0042326//negative regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007264//small GTPase mediated signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0030217//T cell differentiation",GO:0019210//kinase inhibitor activity;GO:0005525//GTP binding;GO:0005095//GTPase inhibitor activity;GO:0017048//Rho GTPase binding;GO:0005515//protein binding,K07873//Leukocyte transendothelial migration
3990,0,0,0,0,0,9,19,32,21,0,0,0,"LIPC;lipase, hepatic",GO:0034364//high-density lipoprotein particle;GO:0005615//extracellular space,GO:0008203//cholesterol metabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0019433//triglyceride catabolic process;GO:0034382//chylomicron remnant clearance;GO:0043691//reverse cholesterol transport;GO:0042632//cholesterol homeostasis;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0034638//phosphatidylcholine catabolic process;GO:0070328//triglyceride homeostasis;GO:0034375//high-density lipoprotein particle remodeling;GO:0034373//intermediate-density lipoprotein particle remodeling;GO:0006633//fatty acid biosynthetic process,GO:0004620//phospholipase activity;GO:0034185//apolipoprotein binding;GO:0030169//low-density lipoprotein particle binding;GO:0008201//heparin binding;GO:0004806//triglyceride lipase activity,K01046//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism;alpha-Linolenic acid metabolism
3991,104,1,0,15,43,44,5,136,60,0,92,0,"LIPE;lipase, hormone-sensitive",GO:0005901//caveola;GO:0005829//cytosol;GO:0005811//lipid particle,GO:0042758//long-chain fatty acid catabolic process;GO:0019433//triglyceride catabolic process;GO:0044281//small molecule metabolic process;GO:0008203//cholesterol metabolic process;GO:0016042//lipid catabolic process;GO:0006468//protein phosphorylation;GO:0046340//diacylglycerol catabolic process,GO:0033878//hormone-sensitive lipase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004806//triglyceride lipase activity,K07188//Insulin signaling pathway
3992,223,0,0,18,57,0,0,0,35,0,0,0,FADS1;fatty acid desaturase 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0055114//oxidation-reduction process;GO:0043651//linoleic acid metabolic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0045595//regulation of cell differentiation;GO:0007267//cell-cell signaling;GO:0044255//cellular lipid metabolic process;GO:0009267//cellular response to starvation;GO:0044281//small molecule metabolic process;GO:0046456//icosanoid biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0006355//regulation of transcription, DNA-templated",GO:0000248//C-5 sterol desaturase activity;GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016491//oxidoreductase activity,K10224//Biosynthesis of unsaturated fatty acids
3993,0,23,0,0,1,5,0,0,19,0,0,0,LLGL2;lethal giant larvae homolog 2 (Drosophila),GO:0005737//cytoplasm,GO:0006887//exocytosis;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0051301//cell division;GO:0007049//cell cycle,GO:0005515//protein binding;GO:0030165//PDZ domain binding,K06094//Tight junction
399473,109,0,0,0,0,0,0,0,20,0,0,0,"SPRED3;sprouty-related, EVH1 domain containing 3",GO:0005886//plasma membrane,GO:0000188//inactivation of MAPK activity;GO:0007275//multicellular organismal development,-,K04703//Jak-STAT signaling pathway
399474,0,323,227,298,545,0,29,161,20,0,394,1,TMEM200B;transmembrane protein 200B,GO:0016021//integral component of membrane,-,-,-
399491,0,0,0,0,0,7,0,0,15,137,13,1,LOC399491;polycystic kidney disease 1 (autosomal dominant) pseudogene,-,-,-,-
3995,0,0,0,0,0,0,8,0,0,0,8,0,FADS3;fatty acid desaturase 3,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006636//unsaturated fatty acid biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0020037//heme binding;GO:0005506//iron ion binding;GO:0016717//oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water",-
399512,87,468,340,580,642,12,37,975,57,179,693,0,"SLC25A35;solute carrier family 25, member 35",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
3996,75,0,0,0,18,55,1,37,41,0,11,0,LLGL1;lethal giant larvae homolog 1 (Drosophila),GO:0030424//axon;GO:0032588//trans-Golgi network membrane;GO:0031901//early endosome membrane;GO:0030864//cortical actin cytoskeleton;GO:0035748//myelin sheath abaxonal region;GO:0000137//Golgi cis cisterna;GO:0000139//Golgi membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0030866//cortical actin cytoskeleton organization;GO:0006461//protein complex assembly;GO:0006887//exocytosis;GO:0032851//positive regulation of Rab GTPase activity;GO:0006893//Golgi to plasma membrane transport;GO:0035090//maintenance of apical/basal cell polarity;GO:0007409//axonogenesis,GO:0005198//structural molecule activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K06094//Tight junction
399664,0,0,0,1,12,17,0,1,0,0,1,0,MEX3D;mex-3 RNA binding family member D,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0010609//mRNA localization resulting in posttranscriptional regulation of gene expression;GO:0061157//mRNA destabilization,GO:0017091//AU-rich element binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
399665,0,28,1,11,0,25,0,0,15,0,0,0,"FAM102A;family with sequence similarity 102, member A",-,-,-,-
399670,90,0,0,0,0,0,3,1,12,0,0,0,RPL13AP17;ribosomal protein L13a pseudogene 17,-,-,-,K02872//Ribosome
399671,0,5,42,76,22,0,63,0,69,0,28,0,HEATR4;HEAT repeat containing 4,-,-,-,-
399687,0,1,0,0,10,15,28,61,27,2,5,205,MYO18A;myosin XVIIIA,GO:0042641//actomyosin;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016459//myosin complex;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0007030//Golgi organization;GO:0043066//negative regulation of apoptotic process;GO:0006259//DNA metabolic process;GO:0048194//Golgi vesicle budding;GO:0031032//actomyosin structure organization;GO:0050714//positive regulation of protein secretion;GO:0016477//cell migration,GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0051015//actin filament binding;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0043531//ADP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
399694,0,0,0,0,0,0,0,0,42,49,0,0,"SHC4;SHC (Src homology 2 domain containing) family, member 4",GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0035556//intracellular signal transduction;GO:0048863//stem cell differentiation;GO:0010468//regulation of gene expression;GO:0008284//positive regulation of cell proliferation;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding,K06279//Alcoholism;Insulin signaling pathway;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Focal adhesion;VEGF signaling pathway;Glioma;ErbB signaling pathway;Neurotrophin signaling pathway;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity
399697,0,0,0,0,0,0,21,0,28,0,0,0,CTXN2;cortexin 2,GO:0016021//integral component of membrane,-,-,-
399717,0,0,0,0,0,8,0,0,0,0,0,0,GATA3-AS1;GATA3 antisense RNA 1,-,-,-,-
399726,0,0,0,0,0,0,0,0,19,0,3,0,CASC10;cancer susceptibility candidate 10,-,-,-,-
399744,0,0,0,0,0,0,52,3,0,147,4,0,LINC00999;long intergenic non-protein coding RNA 999,-,-,-,K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K14209//Protein digestion and absorption;K05185//Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction;GABAergic synapse;Nicotine addiction;Morphine addiction
399746,0,0,0,0,0,0,0,0,0,0,0,9,ACTR3BP5;ACTR3B pseudogene 5,-,-,-,-
399761,0,15,8,0,18,8,0,41,15,0,0,0,BMS1P5;BMS1 pseudogene 5,-,-,-,K14569//Ribosome biogenesis in eukaryotes
3998,0,15,0,44,30,43,0,44,48,157,0,0,"LMAN1;lectin, mannose-binding, 1",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0070062//extracellular vesicular exosome;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0030017//sarcomere;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007029//endoplasmic reticulum organization;GO:0006457//protein folding;GO:0007596//blood coagulation;GO:0034498//early endosome to Golgi transport;GO:0007030//Golgi organization;GO:0044267//cellular protein metabolic process;GO:0032527//protein exit from endoplasmic reticulum;GO:0010638//positive regulation of organelle organization;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006888//ER to Golgi vesicle-mediated transport,GO:0046872//metal ion binding;GO:0005537//mannose binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,K10080//Protein processing in endoplasmic reticulum
399814,0,0,0,0,0,9,0,0,5,0,0,0,C10orf120;chromosome 10 open reading frame 120,-,-,-,-
399815,0,0,0,0,0,0,0,0,27,0,0,0,LOC399815;chromosome 10 open reading frame 88 pseudogene,-,-,-,K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway
399818,0,0,0,29,16,0,0,0,0,29,0,0,METTL10;methyltransferase like 10,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
399823,1,0,0,0,0,21,0,5,15,0,7,0,FOXI2;forkhead box I2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
399827,0,0,0,0,0,26,0,0,0,0,0,0,LINC01164;long intergenic non-protein coding RNA 1164,-,-,-,-
399829,0,0,0,0,0,2,0,1,49,0,0,0,LINC01168;long intergenic non-protein coding RNA 1168,-,-,-,-
399833,2,0,0,0,0,0,0,0,14,0,12,0,SPRNP1;shadow of prion protein homolog (zebrafish) pseudogene 1,-,-,-,-
399844,0,0,0,0,0,0,11,0,0,0,0,0,LINC01002;long intergenic non-protein coding RNA 1002,-,-,-,K05185//Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Nicotine addiction;Morphine addiction;GABAergic synapse
399886,0,0,0,0,0,0,0,0,14,0,0,0,LOC399886;uncharacterized LOC399886,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Biotin metabolism;Arginine and proline metabolism;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
399888,0,0,0,0,0,0,9,0,0,0,2,0,"FAM180B;family with sequence similarity 180, member B",GO:0016021//integral component of membrane,-,-,-
399909,0,1,1,0,0,0,31,1,55,157,11,0,PCNXL3;pecanex-like 3 (Drosophila),GO:0016021//integral component of membrane,-,-,K10955//Vibrio cholerae infection;Amoebiasis
399923,0,0,0,0,0,16,0,0,0,0,0,0,FLJ42102;uncharacterized LOC399923,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
399947,0,0,0,0,0,1,16,0,0,0,0,0,C11orf87;chromosome 11 open reading frame 87,GO:0016021//integral component of membrane,-,-,-
399949,0,0,0,0,0,2,0,0,0,0,0,0,C11orf88;chromosome 11 open reading frame 88,-,-,-,-
399968,0,41,0,0,0,58,38,0,0,0,0,0,PATE4;prostate and testis expressed 4,GO:0001669//acrosomal vesicle;GO:0005615//extracellular space,GO:0050804//regulation of synaptic transmission;GO:0009611//response to wounding,-,-
399979,0,0,0,0,0,20,17,0,10,0,0,0,SNX19;sorting nexin 19,GO:0030659//cytoplasmic vesicle membrane,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,-
40,0,0,0,0,8,15,2,21,13,0,10,0,ASIC2;acid-sensing (proton-gated) ion channel 2,GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043197//dendritic spine;GO:0043025//neuronal cell body,GO:0019229//regulation of vasoconstriction;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0007602//phototransduction;GO:0050915//sensory perception of sour taste;GO:0010468//regulation of gene expression;GO:0034220//ion transmembrane transport;GO:0051965//positive regulation of synapse assembly;GO:0015672//monovalent inorganic cation transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0035418//protein localization to synapse;GO:0003026//regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback;GO:0007422//peripheral nervous system development;GO:0001101//response to acid chemical;GO:0030193//regulation of blood coagulation;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0007605//sensory perception of sound;GO:0010447//response to acidic pH,GO:0022839//ion gated channel activity;GO:0015280//ligand-gated sodium channel activity;GO:0005515//protein binding;GO:0005248//voltage-gated sodium channel activity,K04828//Taste transduction
400,0,0,1,40,160,0,0,0,0,0,0,0,ARL1;ADP-ribosylation factor-like 1,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network,"GO:0006184//GTP catabolic process;GO:0034067//protein localization to Golgi apparatus;GO:0007030//Golgi organization;GO:0007264//small GTPase mediated signal transduction;GO:0048193//Golgi vesicle transport;GO:0031584//activation of phospholipase D activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0009404//toxin metabolic process",GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019904//protein domain specific binding;GO:0008047//enzyme activator activity,-
4000,49,29,2,0,20,20,0,0,21,169,0,0,LMNA;lamin A/C,GO:0005737//cytoplasm;GO:0005652//nuclear lamina;GO:0005654//nucleoplasm;GO:0005638//lamin filament;GO:0005882//intermediate filament;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016607//nuclear speck,GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0071456//cellular response to hypoxia;GO:0006915//apoptotic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0034504//protein localization to nucleus;GO:0007084//mitotic nuclear envelope reassembly;GO:0090343//positive regulation of cell aging;GO:0044267//cellular protein metabolic process;GO:0000278//mitotic cell cycle;GO:0007517//muscle organ development;GO:0007077//mitotic nuclear envelope disassembly;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0030334//regulation of cell migration;GO:0035105//sterol regulatory element binding protein import into nucleus;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0055015//ventricular cardiac muscle cell development,GO:0005198//structural molecule activity;GO:0005515//protein binding,K12641//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC)
400043,69,0,0,0,0,0,0,2,0,0,0,0,LOC400043;uncharacterized LOC400043,-,-,-,-
400058,0,0,0,0,0,8,0,0,14,0,3,0,"MKRN9P;makorin ring finger protein 9, pseudogene",-,-,-,-
400073,1,0,0,11,0,37,0,0,0,0,1,0,C12orf76;chromosome 12 open reading frame 76,-,-,-,-
4001,0,0,0,3,0,17,20,0,16,0,3,0,LMNB1;lamin B1,GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005637//nuclear inner membrane;GO:0005638//lamin filament;GO:0016020//membrane,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006915//apoptotic process,GO:0043274//phospholipase binding;GO:0005198//structural molecule activity,-
400110,0,0,0,0,0,35,35,0,10,100,2,0,"ANKRD20A19P;ankyrin repeat domain 20 family, member A19, pseudogene",-,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
400120,0,0,0,0,10,7,19,0,38,0,0,0,SERTM1;serine-rich and transmembrane domain containing 1,GO:0016021//integral component of membrane,-,-,-
400165,0,0,0,0,10,17,15,0,6,0,0,0,ATP11AUN;ATP11A upstream neighbor,-,-,-,-
400224,0,0,0,0,0,0,0,0,0,72,14,1,"PLEKHD1;pleckstrin homology domain containing, family D (with coiled-coil domains) member 1",-,-,-,-
400258,123,0,0,0,0,0,29,0,24,0,0,0,C14orf180;chromosome 14 open reading frame 180,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
400322,0,0,0,0,9,57,1,0,28,0,1,1,HERC2P2;hect domain and RLD 2 pseudogene 2,-,-,-,K10595//Ubiquitin mediated proteolysis
400359,0,0,0,0,0,0,16,0,18,0,0,0,C15orf53;chromosome 15 open reading frame 53,-,-,-,-
4004,0,0,0,0,0,0,40,0,4,0,13,0,LMO1;LIM domain only 1 (rhombotin 1),GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0008270//zinc ion binding,K15612//Transcriptional misregulation in cancer
400410,0,69,50,86,178,0,0,416,28,128,269,0,ST20;suppressor of tumorigenicity 20,GO:0005741//mitochondrial outer membrane,GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043066//negative regulation of apoptotic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K02162//NF-kappa B signaling pathway;Transcriptional misregulation in cancer
400451,0,17,0,19,1,8,0,0,0,0,19,0,"FAM174B;family with sequence similarity 174, member B",GO:0016021//integral component of membrane,-,-,-
4005,7,0,0,0,0,0,0,0,10,0,3,0,LMO2;LIM domain only 2 (rhombotin-like 1),GO:0005634//nucleus;GO:0005667//transcription factor complex,GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0035162//embryonic hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0097067//cellular response to thyroid hormone stimulus;GO:0007275//multicellular organismal development;GO:0045647//negative regulation of erythrocyte differentiation,GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0070888//E-box binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0043425//bHLH transcription factor binding;GO:0048037//cofactor binding,K15612//Transcriptional misregulation in cancer
400506,0,23,0,10,49,0,0,10,13,0,0,0,KNOP1;lysine-rich nucleolar protein 1,GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
400511,87,0,0,0,0,11,0,0,20,0,0,65,LOC400511;uncharacterized LOC400511,-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
400553,0,0,0,0,0,0,0,0,16,0,0,0,LOC400553;uncharacterized LOC400553,-,-,-,-
400566,0,0,0,0,0,18,10,0,9,0,0,0,C17orf97;chromosome 17 open reading frame 97,-,-,-,K03254//RNA transport
400569,0,0,0,0,11,0,23,0,22,0,6,0,MED11;mediator complex subunit 11,GO:0016592//mediator complex,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,-
400578,0,0,0,0,0,0,16,0,28,0,1,0,KRT16P2;keratin 16 pseudogene 2,-,-,-,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
400579,0,0,0,0,0,6,5,0,21,3,0,0,FLJ35934;FLJ35934,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K11447//Transcriptional misregulation in cancer
400581,0,0,0,0,0,0,0,0,15,0,0,0,GRAPL;GRB2-related adaptor protein-like,-,-,-,K04364//Fc epsilon RI signaling pathway;Acute myeloid leukemia;Jak-STAT signaling pathway;B cell receptor signaling pathway;Neurotrophin signaling pathway;Hepatitis C;Non-small cell lung cancer;Endometrial cancer;MAPK signaling pathway - fly;Osteoclast differentiation;Focal adhesion;Dorso-ventral axis formation;Glioma;Insulin signaling pathway;Gap junction;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Alcoholism;Prostate cancer;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Renal cell carcinoma;ErbB signaling pathway
400591,0,0,0,0,0,35,0,0,21,0,0,0,C17orf102;chromosome 17 open reading frame 102,-,-,-,-
400618,0,0,0,0,0,12,0,0,0,0,0,0,SOX9-AS1;SOX9 antisense RNA 1,-,-,-,K04257//Olfactory transduction
400629,0,0,0,0,0,0,0,2,0,0,0,0,TEX19;testis expressed 19,GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0007126//meiotic nuclear division;GO:0007283//spermatogenesis,-,-
400654,0,0,0,0,0,0,35,0,0,0,0,0,LOC400654;uncharacterized LOC400654,-,-,-,-
400658,0,0,0,0,0,17,0,0,1,0,5,0,FLJ44313;FLJ44313 protein,-,-,-,-
400668,62,0,0,0,0,0,33,0,15,0,0,0,"PRSS57;protease, serine, 57",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01353//Autoimmune thyroid disease;Allograft rejection;Graft-versus-host disease;Natural killer cell mediated cytotoxicity;Type I diabetes mellitus;Transcriptional misregulation in cancer;K01334//Complement and coagulation cascades;Staphylococcus aureus infection
400673,0,16,0,0,0,0,0,0,0,0,2,0,VMAC;vimentin-type intermediate filament associated coiled-coil protein,GO:0005737//cytoplasm,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
400696,0,0,0,0,0,0,0,0,12,0,0,0,LGALS17A;Charcot-Leyden crystal protein pseudogene,-,-,-,-
4007,0,0,0,22,94,0,30,0,34,0,61,0,PRICKLE3;prickle homolog 3 (Drosophila),-,-,GO:0008270//zinc ion binding;GO:0005515//protein binding,K04511//Wnt signaling pathway
400709,0,0,0,5,9,4,15,0,0,0,24,0,SIGLEC16;sialic acid binding Ig-like lectin 16 (gene/pseudogene),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0045087//innate immune response,GO:0030246//carbohydrate binding,-
400713,0,0,0,8,0,22,0,0,0,0,0,0,ZNF880;zinc finger protein 880,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003676//nucleic acid binding,-
400720,75,0,1,32,58,15,0,0,32,0,0,0,ZNF772;zinc finger protein 772,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
400728,0,66,0,18,33,1,0,135,0,0,25,0,"FAM87B;family with sequence similarity 87, member B",GO:0016021//integral component of membrane,-,-,-
400735,0,0,0,0,0,0,0,1,1,0,0,0,PRAMEF4;PRAME family member 4,-,"GO:0043066//negative regulation of apoptotic process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0008284//positive regulation of cell proliferation",GO:0042974//retinoic acid receptor binding,-
400745,0,0,76,9,0,0,0,0,82,0,13,0,SH2D5;SH2 domain containing 5,-,-,-,-
400746,0,8,0,18,3,0,0,44,72,0,9,0,NCMAP;noncompact myelin associated protein,GO:0033270//paranode region of axon;GO:0005887//integral component of plasma membrane;GO:0043220//Schmidt-Lanterman incisure,GO:0032290//peripheral nervous system myelin formation;GO:0031643//positive regulation of myelination,GO:0019911//structural constituent of myelin sheath,K06264//ECM-receptor interaction;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
400757,0,0,0,0,0,0,28,0,19,0,3,0,C1orf141;chromosome 1 open reading frame 141,-,-,-,-
400759,1,0,0,0,0,0,0,0,21,0,0,0,"GBP1P1;guanylate binding protein 1, interferon-inducible pseudogene 1",-,-,-,-
400793,0,0,0,0,39,21,23,0,24,78,7,0,C1orf226;chromosome 1 open reading frame 226,-,-,-,K07989//Natural killer cell mediated cytotoxicity
4008,0,108,0,35,183,48,0,0,37,0,0,0,LMO7;LIM domain 7,GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005925//focal adhesion,GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,K06084//Adherens junction
400804,0,0,0,0,0,19,34,0,41,0,0,0,C1orf140;uncharacterized LOC400804,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
400818,0,0,0,2,5,3,0,0,3,0,0,0,"NBPF9;neuroblastoma breakpoint family, member 9",-,-,-,-
400823,0,0,0,0,0,0,12,0,0,0,0,0,"FAM177B;family with sequence similarity 177, member B",-,-,-,-
400830,0,0,0,0,13,0,38,0,63,0,0,0,"DEFB132;defensin, beta 132",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
400831,0,0,0,0,6,22,0,0,15,0,2,0,C20orf202;chromosome 20 open reading frame 202,-,-,-,-
400863,0,0,0,0,0,30,0,0,0,0,0,0,LOC400863;uncharactered LOC400863,-,-,-,-
400891,0,0,0,0,0,13,0,59,14,0,1,0,LOC400891;leucine-rich repeat-containing protein LOC400891,-,-,-,K08727//Pertussis;Epithelial cell signaling in Helicobacter pylori infection;NOD-like receptor signaling pathway;Shigellosis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
400892,0,1,6,0,0,0,1,139,0,0,4,0,BCRP2;breakpoint cluster region pseudogene 2,-,-,-,K08878//Pathways in cancer;Chronic myeloid leukemia
4009,0,0,23,15,4,0,0,0,38,134,7,0,"LMX1A;LIM homeobox transcription factor 1, alpha",GO:0005634//nucleus,"GO:0071542//dopaminergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0030901//midbrain development;GO:0021549//cerebellum development;GO:0001558//regulation of cell growth;GO:0021542//dentate gyrus development;GO:0007411//axon guidance;GO:0021953//central nervous system neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding,-
400931,0,0,0,0,0,0,26,55,11,1,0,0,MIRLET7BHG;MIRLET7B host gene (non-protein coding),-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
400932,16,0,0,0,0,6,61,0,0,133,0,0,LINC00898;long intergenic non-protein coding RNA 898,-,-,-,-
400935,0,0,0,0,0,19,0,1,42,0,9,0,IL17REL;interleukin 17 receptor E-like,-,-,-,-
400950,0,0,0,0,0,0,72,82,26,0,0,0,C2orf91;chromosome 2 open reading frame 91,-,-,-,K09299//Transcriptional misregulation in cancer;K04257//Olfactory transduction
400954,64,0,48,0,14,1,78,124,89,0,10,0,EML6;echinoderm microtubule associated protein like 6,GO:0005737//cytoplasm;GO:0005874//microtubule,-,-,-
400960,0,0,0,0,0,0,0,62,0,0,0,0,PCBP1-AS1;PCBP1 antisense RNA 1,-,-,-,K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
400961,0,82,2,40,132,2,11,72,64,0,0,0,PAIP2B;poly(A) binding protein interacting protein 2B,GO:0005737//cytoplasm,GO:0045947//negative regulation of translational initiation,"GO:0000900//translation repressor activity, nucleic acid binding;GO:0005515//protein binding",K06264//ECM-receptor interaction
400966,0,0,0,6,9,20,0,0,0,0,0,0,RGPD1;RANBP2-like and GRIP domain containing 1,-,GO:0000042//protein targeting to Golgi,-,K12172//RNA transport
401,1,0,0,0,0,0,0,0,2,0,0,0,PHOX2A;paired-like homeobox 2a,GO:0000790//nuclear chromatin,"GO:0021703//locus ceruleus development;GO:0043576//regulation of respiratory gaseous exchange;GO:0021623//oculomotor nerve formation;GO:0006351//transcription, DNA-templated;GO:0071542//dopaminergic neuron differentiation;GO:0003357//noradrenergic neuron differentiation;GO:0021642//trochlear nerve formation;GO:0048485//sympathetic nervous system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030901//midbrain development;GO:0021523//somatic motor neuron differentiation",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
4010,49,0,0,0,6,0,0,52,58,0,9,0,"LMX1B;LIM homeobox transcription factor 1, beta",GO:0005634//nucleus,"GO:0001701//in utero embryonic development;GO:0071542//dopaminergic neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0021587//cerebellum morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0008283//cell proliferation;GO:0030199//collagen fibril organization;GO:0002930//trabecular meshwork development;GO:0035265//organ growth;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021954//central nervous system neuron development;GO:0030182//neuron differentiation;GO:0001764//neuron migration;GO:0035108//limb morphogenesis;GO:0007275//multicellular organismal development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
401010,54,0,0,0,0,0,25,0,8,0,8,0,LOC401010;nucleolar complex associated 2 homolog (S. cerevisiae) pseudogene,-,-,-,-
401024,2,0,0,0,25,43,0,0,144,0,12,0,FSIP2;fibrous sheath interacting protein 2,-,-,-,-
401027,0,0,0,0,0,0,0,0,19,0,0,0,C2orf66;chromosome 2 open reading frame 66,GO:0005576//extracellular region,-,-,-
401036,13,0,0,0,0,0,0,0,14,0,22,0,ASB18;ankyrin repeat and SOCS box containing 18,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
401039,0,0,0,0,0,17,11,0,25,0,0,0,FLJ43879;FLJ43879 protein,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
401067,69,0,0,0,0,0,0,0,10,0,0,0,IQCF3;IQ motif containing F3,-,-,-,-
401074,0,0,0,1,0,0,5,41,0,0,0,0,LINC00960;long intergenic non-protein coding RNA 960,-,-,-,K07375//Phagosome;Gap junction;Pathogenic Escherichia coli infection
401089,0,0,0,0,0,0,0,80,15,0,9,0,FOXL2NB;FOXL2 neighbor,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
401093,42,337,90,257,449,10,34,16,111,86,394,0,MBNL1-AS1;MBNL1 antisense RNA 1,-,-,-,-
401097,0,0,0,0,0,0,0,0,1,0,0,0,C3orf80;chromosome 3 open reading frame 80,GO:0016021//integral component of membrane,-,-,-
401105,93,0,0,0,0,14,0,0,14,0,0,0,FLJ42393;uncharacterized LOC401105,-,-,-,-
401115,0,0,0,0,0,0,0,0,0,1,0,0,C4orf48;chromosome 4 open reading frame 48,GO:0005576//extracellular region,-,-,-
401124,0,0,0,0,0,15,22,0,0,0,18,0,DTHD1;death domain containing 1,-,GO:0007165//signal transduction,-,K10130//p53 signaling pathway;NF-kappa B signaling pathway
401127,0,0,0,0,0,0,24,0,0,0,0,0,LOC401127;WD repeat domain 5 pseudogene,-,-,-,-
401135,0,0,0,0,0,0,1,0,13,0,0,0,SYT14P1;synaptotagmin XIV pseudogene 1,-,-,-,K15290//Synaptic vesicle cycle
401136,0,0,0,0,0,0,43,0,21,0,0,0,"TMPRSS11BNL;TMPRSS11B N-terminal like, pseudogene",-,-,-,-
401137,0,0,0,0,0,19,0,0,66,0,0,0,PRR27;proline rich 27,GO:0070062//extracellular vesicular exosome,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K11447//Transcriptional misregulation in cancer
401138,0,0,0,0,1,2,0,62,49,0,8,0,AMTN;amelotin,GO:0005578//proteinaceous extracellular matrix;GO:0005911//cell-cell junction;GO:0005605//basal lamina,GO:0042475//odontogenesis of dentin-containing tooth;GO:0031214//biomineral tissue development;GO:0007155//cell adhesion,-,-
401145,0,0,0,1,6,0,0,0,55,0,12,0,CCSER1;coiled-coil serine-rich protein 1,-,-,-,-
401149,0,0,0,0,0,8,0,0,39,60,11,0,LINC01061;long intergenic non-protein coding RNA 1061,-,-,-,-
401152,0,92,3,38,227,0,17,0,17,102,8,0,C4orf3;chromosome 4 open reading frame 3,GO:0016021//integral component of membrane,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
401190,1,0,0,0,8,52,0,0,7,0,0,0,RGS7BP;regulator of G-protein signaling 7 binding protein,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0009968//negative regulation of signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,-,-
4012,0,0,0,36,79,1,43,0,3,239,30,159,LNPEP;leucyl/cystinyl aminopeptidase,GO:0005829//cytosol;GO:0005622//intracellular;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0031905//early endosome lumen;GO:0005765//lysosomal membrane,"GO:0000209//protein polyubiquitination;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0061024//membrane organization;GO:0006508//proteolysis;GO:0007565//female pregnancy;GO:0007267//cell-cell signaling;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0030163//protein catabolic process",GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity,K01257//Renin-angiotensin system
401207,0,0,0,0,14,0,0,0,8,0,0,0,C5orf63;chromosome 5 open reading frame 63,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,-,"K00626//Valine, leucine and isoleucine degradation;Fat digestion and absorption;Carbon fixation pathways in prokaryotes;Butanoate metabolism;Two-component system;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;Pyruvate metabolism;Propanoate metabolism;Fatty acid metabolism;Lysine degradation;Benzoate degradation;Terpenoid backbone biosynthesis;Microbial metabolism in diverse environments;Synthesis and degradation of ketone bodies;Biosynthesis of secondary metabolites;Tryptophan metabolism"
401232,0,0,0,0,0,0,0,33,25,185,0,0,LINC01011;long intergenic non-protein coding RNA 1011,-,-,-,-
401233,1,20,0,0,27,0,0,0,17,0,13,295,HTATSF1P2;HIV-1 Tat specific factor 1 pseudogene 2,-,-,-,-
401236,0,0,0,0,0,0,15,0,4,0,0,0,STMND1;stathmin domain containing 1,-,GO:0031110//regulation of microtubule polymerization or depolymerization,-,-
401253,100,0,0,0,0,0,0,0,28,0,0,1,LINC00336;long intergenic non-protein coding RNA 336,-,-,-,-
401258,0,0,0,0,0,19,0,1,10,128,0,0,"RAB44;RAB44, member RAS oncogene family",GO:0005886//plasma membrane,GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,K07901//Pancreatic secretion
401260,0,0,0,0,0,0,0,0,15,250,0,0,LINC00951;long intergenic non-protein coding RNA 951,-,-,-,-
401265,210,0,0,5,0,0,0,0,39,0,0,0,KLHL31;kelch-like family member 31,-,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
401285,0,0,0,0,0,0,0,0,1,0,0,0,TCP10L2;t-complex 10-like 2,-,-,-,-
401286,54,0,0,0,0,0,14,48,11,164,33,0,LOC401286;uncharacterized LOC401286,-,-,-,-
401288,0,0,0,0,0,8,19,0,62,0,0,0,LINC00242;long intergenic non-protein coding RNA 242,-,-,-,-
4013,6,0,1,2,28,13,16,0,5,0,0,0,VWA5A;von Willebrand factor A domain containing 5A,-,-,-,K10798//Base excision repair;NF-kappa B signaling pathway
401303,0,0,0,0,4,0,0,0,0,0,11,0,"ZNF815P;zinc finger protein 815, pseudogene",-,-,-,-
401321,0,0,0,0,0,16,1,0,15,0,10,0,LINC00997;long intergenic non-protein coding RNA 997,-,-,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
401324,0,0,0,0,0,0,7,47,20,0,0,0,LOC401324;uncharacterized LOC401324,-,-,-,-
401331,1,10,4,25,0,0,0,82,70,2,99,0,"RASA4CP;RAS p21 protein activator 4C, pseudogene",-,-,-,K08053//MAPK signaling pathway
401335,0,0,0,0,0,0,0,0,36,0,0,0,C7orf65;chromosome 7 open reading frame 65,-,-,-,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
401337,0,0,0,0,0,0,1,0,9,0,0,0,LINC01446;long intergenic non-protein coding RNA 1446,-,-,-,-
401387,0,0,0,0,0,42,0,0,0,0,15,0,LRRD1;leucine-rich repeats and death domain containing 1,-,GO:0007165//signal transduction,-,K01768//Purine metabolism;Meiosis - yeast
401388,0,0,0,0,0,0,0,66,12,0,5,0,C7orf76;chromosome 7 open reading frame 76,-,-,-,-
401397,0,27,0,1,27,20,0,0,6,0,0,0,LINC00998;long intergenic non-protein coding RNA 998,GO:0016021//integral component of membrane,-,-,-
401399,0,0,0,0,0,15,19,0,9,2,0,47,PRRT4;proline-rich transmembrane protein 4,GO:0016021//integral component of membrane,-,-,K14573//Ribosome biogenesis in eukaryotes
4014,0,0,0,0,0,16,0,0,0,0,0,0,LOR;loricrin,GO:0005654//nucleoplasm;GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation,"GO:0005515//protein binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity;GO:0005200//structural constituent of cytoskeleton",-
401409,0,1,0,0,0,0,0,0,0,0,1,0,"RAB19;RAB19, member RAS oncogene family",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
401427,0,0,0,0,14,0,0,0,9,0,0,0,"OR2A7;olfactory receptor, family 2, subfamily A, member 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
401431,0,0,41,4,0,33,0,194,56,13,0,0,ATP6V0E2-AS1;ATP6V0E2 antisense RNA 1,-,-,-,-
401447,0,0,1,0,0,5,0,0,6,0,0,0,"USP17L1P;ubiquitin specific peptidase 17-like family member 1, pseudogene",GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process,GO:0036459//ubiquitinyl hydrolase activity;GO:0008234//cysteine-type peptidase activity,-
401466,3,0,58,18,37,0,20,0,0,0,8,0,C8orf59;chromosome 8 open reading frame 59,-,-,-,-
401474,0,0,0,0,16,1,21,0,103,41,0,0,SAMD12;sterile alpha motif domain containing 12,-,-,-,-
401494,0,0,0,0,6,8,0,0,6,0,1,640,PTPLAD2;protein tyrosine phosphatase-like A domain containing 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006633//fatty acid biosynthetic process,GO:0016829//lyase activity,K10703//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
401498,107,0,0,0,0,21,0,0,27,2,0,0,TMEM215;transmembrane protein 215,GO:0016021//integral component of membrane,-,-,-
4015,0,0,0,12,0,0,0,0,44,197,0,0,LOX;lysyl oxidase,GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0001568//blood vessel development;GO:0048251//elastic fiber assembly;GO:0006464//cellular protein modification process;GO:0042493//response to drug;GO:0030198//extracellular matrix organization;GO:0048545//response to steroid hormone;GO:0030199//collagen fibril organization;GO:0055114//oxidation-reduction process;GO:0030324//lung development;GO:0042060//wound healing,GO:0005507//copper ion binding;GO:0004720//protein-lysine 6-oxidase activity;GO:0005515//protein binding,-
401505,0,0,0,0,13,0,0,0,0,0,0,0,TOMM5;translocase of outer mitochondrial membrane 5 homolog (yeast),GO:0005742//mitochondrial outer membrane translocase complex;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process,GO:0008565//protein transporter activity,-
401509,1,0,0,0,0,0,1,0,2,0,15,0,"ZNF658B;zinc finger protein 658B, pseudogene",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
401535,0,0,0,0,0,0,0,0,16,0,0,0,C9orf170;chromosome 9 open reading frame 170,-,-,-,-
401541,0,115,55,70,112,27,12,0,34,0,243,0,CENPP;centromere protein P,"GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0005654//nucleoplasm",GO:0006334//nucleosome assembly;GO:0000278//mitotic cell cycle;GO:0034080//CENP-A containing nucleosome assembly,-,-
401546,0,58,0,25,51,0,0,0,0,0,1,0,C9orf152;chromosome 9 open reading frame 152,-,-,-,-
401548,218,1,1,17,27,53,46,0,36,2,3,0,SNX30;sorting nexin family member 30,GO:0005768//endosome,GO:0006915//apoptotic process;GO:0006886//intracellular protein transport,GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K08545//MAPK signaling pathway - fly
401551,0,52,21,58,153,23,0,0,3,148,18,0,WDR38;WD repeat domain 38,-,GO:0002244//hematopoietic progenitor cell differentiation,-,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
401562,0,0,0,0,0,14,14,0,10,0,18,0,LCNL1;lipocalin-like 1,-,-,-,K01830//Arachidonic acid metabolism;Metabolic pathways
401563,0,0,0,0,0,0,0,0,30,0,0,0,C9orf139;chromosome 9 open reading frame 139,-,-,-,K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
401565,1,1481,496,1269,1938,32,38,431,196,118,1048,1,"FAM166A;family with sequence similarity 166, member A",GO:0005634//nucleus,-,-,-
401577,0,0,0,0,0,20,0,0,50,0,0,0,CD99P1;CD99 molecule pseudogene 1,-,-,-,K06520//Cell adhesion molecules (CAMs);Leukocyte transendothelial migration
4016,0,0,0,9,23,0,0,0,7,0,2,0,LOXL1;lysyl oxidase-like 1,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0018277//protein deamination;GO:0055114//oxidation-reduction process;GO:0030198//extracellular matrix organization,"GO:0016641//oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor;GO:0005507//copper ion binding",-
401612,0,0,0,0,0,0,22,0,29,91,10,0,"SLC25A53;solute carrier family 25, member 53",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006810//transport,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
401613,0,0,0,0,0,0,1,0,38,0,2,0,LINC00890;long intergenic non-protein coding RNA 890,-,-,-,-
401647,38,0,0,0,0,0,0,0,45,0,0,0,"GOLGA7B;golgin A7 family, member B",GO:0000139//Golgi membrane,-,-,K05546//N-Glycan biosynthesis;Protein processing in endoplasmic reticulum;Metabolic pathways
401666,0,0,0,0,0,0,0,0,27,0,0,0,"OR51A4;olfactory receptor, family 51, subfamily A, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
4017,0,23,0,14,0,3,0,51,21,0,27,0,LOXL2;lysyl oxidase-like 2,GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0030199//collagen fibril organization;GO:0018277//protein deamination;GO:0006351//transcription, DNA-templated;GO:0001837//epithelial to mesenchymal transition;GO:0032332//positive regulation of chondrocyte differentiation;GO:0006464//cellular protein modification process;GO:0001935//endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0007155//cell adhesion;GO:0055114//oxidation-reduction process;GO:0006898//receptor-mediated endocytosis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001666//response to hypoxia;GO:0043542//endothelial cell migration;GO:0046688//response to copper ion;GO:0016570//histone modification;GO:0007568//aging",GO:0035064//methylated histone binding;GO:0070492//oligosaccharide binding;GO:0004720//protein-lysine 6-oxidase activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0009055//electron carrier activity;GO:0005515//protein binding;GO:0005507//copper ion binding;GO:0005044//scavenger receptor activity,-
401720,0,0,0,0,0,21,1,59,12,0,1,0,FIGNL2;fidgetin-like 2,-,-,GO:0005524//ATP binding,-
4018,0,0,0,0,0,25,0,0,11,0,0,268,"LPA;lipoprotein, Lp(a)",GO:0034358//plasma lipoprotein particle;GO:0005576//extracellular region,GO:0044281//small molecule metabolic process;GO:0008015//blood circulation;GO:0042157//lipoprotein metabolic process;GO:0006629//lipid metabolic process;GO:0006508//proteolysis;GO:0006869//lipid transport;GO:0010951//negative regulation of endopeptidase activity;GO:0006898//receptor-mediated endocytosis,GO:0034185//apolipoprotein binding;GO:0004866//endopeptidase inhibitor activity;GO:0001968//fibronectin binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008201//heparin binding,-
401884,0,14,0,0,0,0,0,0,0,0,0,0,MGC57346;uncharacterized LOC401884,-,-,-,K07937//Vibrio cholerae infection;Legionellosis
401934,0,0,0,0,0,0,0,1,0,0,11,0,RNF223;ring finger protein 223,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,K14683//Mineral absorption
401944,0,0,0,0,0,36,0,0,83,0,0,0,LDLRAD2;low density lipoprotein receptor class A domain containing 2,GO:0016021//integral component of membrane,-,-,K06255//ECM-receptor interaction
401992,0,0,0,0,11,28,0,0,15,0,0,0,"OR2T2;olfactory receptor, family 2, subfamily T, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
401994,0,0,0,0,0,0,0,0,8,0,0,0,"OR14I1;olfactory receptor, family 14, subfamily I, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
402,0,0,0,0,1,0,0,0,0,0,0,0,ARL2;ADP-ribosylation factor-like 2,GO:0016328//lateral plasma membrane;GO:0005813//centrosome;GO:0005634//nucleus;GO:0072372//primary cilium;GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome,GO:0031116//positive regulation of microtubule polymerization;GO:0007264//small GTPase mediated signal transduction;GO:0051457//maintenance of protein location in nucleus;GO:0007049//cell cycle;GO:0070830//tight junction assembly;GO:0007021//tubulin complex assembly;GO:0006184//GTP catabolic process;GO:0034260//negative regulation of GTPase activity;GO:0051297//centrosome organization;GO:0010811//positive regulation of cell-substrate adhesion,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005095//GTPase inhibitor activity,-
402055,1,17,0,2,52,0,0,0,9,0,0,0,SRRD;SRR1 domain containing,-,GO:0048511//rhythmic process,-,-
402117,0,0,0,0,0,13,0,0,0,0,0,0,VWC2L;von Willebrand factor C domain containing protein 2-like,GO:0005615//extracellular space;GO:0045202//synapse;GO:0030054//cell junction;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0045666//positive regulation of neuron differentiation;GO:0030514//negative regulation of BMP signaling pathway,-,K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption;K03900//ECM-receptor interaction;Complement and coagulation cascades;Focal adhesion;K13908//Salivary secretion
402135,0,0,0,0,0,0,0,82,0,0,0,0,"OR5K2;olfactory receptor, family 5, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
402160,0,0,0,0,0,15,59,0,24,0,0,0,LOC402160;uncharacterized LOC402160,-,-,-,-
402176,0,0,0,0,0,0,33,0,4,0,0,0,RPL21P44;ribosomal protein L21 pseudogene 44,-,-,-,K02889//Ribosome
4023,0,0,44,0,0,0,18,68,118,0,13,0,LPL;lipoprotein lipase,GO:0034361//very-low-density lipoprotein particle;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0042627//chylomicron;GO:0031225//anchored component of membrane,"GO:0006633//fatty acid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0042157//lipoprotein metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0070328//triglyceride homeostasis;GO:0006641//triglyceride metabolic process;GO:0042493//response to drug;GO:0001523//retinoid metabolic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010886//positive regulation of cholesterol storage;GO:0010890//positive regulation of sequestering of triglyceride;GO:0034372//very-low-density lipoprotein particle remodeling;GO:0044281//small molecule metabolic process;GO:0009409//response to cold;GO:0034371//chylomicron remodeling;GO:0007603//phototransduction, visible light;GO:0019433//triglyceride catabolic process",GO:0017129//triglyceride binding;GO:0034185//apolipoprotein binding;GO:0005102//receptor binding;GO:0004620//phospholipase activity;GO:0004806//triglyceride lipase activity;GO:0004465//lipoprotein lipase activity;GO:0008201//heparin binding;GO:0005515//protein binding,K01059//PPAR signaling pathway;Glycerolipid metabolism;Alzheimer's disease
402381,0,0,0,0,0,0,0,40,37,129,11,0,SOHLH1;spermatogenesis and oogenesis specific basic helix-loop-helix 1,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001541//ovarian follicle development;GO:0048477//oogenesis;GO:0007283//spermatogenesis",GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
402415,0,0,0,0,0,0,12,0,11,0,0,0,"XKRX;XK, Kell blood group complex subunit-related, X-linked",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K08008//Leukocyte transendothelial migration;Phagosome;Osteoclast differentiation
402483,4,0,0,0,0,1,0,7,22,0,16,146,LINC01000;long intergenic non-protein coding RNA 1000,-,-,-,K11447//Transcriptional misregulation in cancer
4025,3,0,0,0,0,3,0,49,20,0,10,0,LPO;lactoperoxidase,GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0042742//defense response to bacterium;GO:0018969//thiocyanate metabolic process;GO:0006979//response to oxidative stress;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0036393//thiocyanate peroxidase activity;GO:0020037//heme binding,K12550//Salivary secretion
402569,0,0,0,0,0,0,0,0,58,0,3,0,KPNA7;karyopherin alpha 7 (importin alpha 8),GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0019221//cytokine-mediated signaling pathway;GO:0006606//protein import into nucleus,GO:0008565//protein transporter activity,K15043//Influenza A
402573,0,0,0,0,0,18,0,0,0,0,0,0,C7orf61;chromosome 7 open reading frame 61,GO:0005634//nucleus,-,-,-
4026,0,158,5,171,605,24,27,22,83,1,17,54,LPP;LIM domain containing preferred translocation partner in lipoma,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0008270//zinc ion binding,K12792//NOD-like receptor signaling pathway
402635,90,0,0,0,0,0,0,0,0,0,0,0,GRIFIN;galectin-related inter-fiber protein,-,-,GO:0030246//carbohydrate binding,-
402665,0,0,0,0,6,0,37,0,45,0,6,0,IGLON5;IgLON family member 5,GO:0005576//extracellular region,-,-,-
402778,0,0,0,0,2,14,0,0,4,0,2,0,IFITM10;interferon induced transmembrane protein 10,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0009607//response to biotic stimulus,-,K06566//B cell receptor signaling pathway
403,0,11,1,0,34,12,0,0,21,0,0,0,ARL3;ADP-ribosylation factor-like 3,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005881//cytoplasmic microtubule;GO:0000139//Golgi membrane;GO:0005813//centrosome;GO:0030496//midbody;GO:0072372//primary cilium;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0005876//spindle microtubule,GO:0007264//small GTPase mediated signal transduction;GO:0060271//cilium morphogenesis;GO:0000910//cytokinesis;GO:0007224//smoothened signaling pathway;GO:0042073//intraciliary transport;GO:0001822//kidney development;GO:0006184//GTP catabolic process;GO:0042461//photoreceptor cell development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0046872//metal ion binding;GO:0019003//GDP binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
403253,0,0,0,0,0,0,0,0,14,0,0,0,"OR4A47;olfactory receptor, family 4, subfamily A, member 47",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
403257,0,0,0,0,0,0,0,1,4,0,0,0,"OR4C45;olfactory receptor, family 4, subfamily C, member 45",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
403273,0,0,0,0,0,0,0,0,17,0,0,0,"OR5H14;olfactory receptor, family 5, subfamily H, member 14",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
403277,0,0,0,0,0,0,0,0,12,0,0,0,"OR5K3;olfactory receptor, family 5, subfamily K, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
403278,0,0,0,0,0,1,0,0,0,0,0,0,"OR5K4;olfactory receptor, family 5, subfamily K, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
403282,0,0,0,0,0,0,0,0,14,0,0,0,"OR6C65;olfactory receptor, family 6, subfamily C, member 65",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
403284,85,0,0,0,0,0,0,0,21,0,0,0,"OR6C68;olfactory receptor, family 6, subfamily C, member 68",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
4033,28,0,0,3,0,16,0,0,0,0,0,0,LRMP;lymphoid-restricted membrane protein,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005694//chromosome;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane;GO:0000922//spindle pole;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope,GO:0007338//single fertilization;GO:0002376//immune system process;GO:0006903//vesicle targeting;GO:0006906//vesicle fusion,-,K12337//Vascular smooth muscle contraction
403313,0,0,52,0,25,0,0,29,27,0,11,0,PPAPDC2;phosphatidic acid phosphatase type 2 domain containing 2,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
403314,0,0,0,0,5,0,0,0,0,0,0,0,"APOBEC4;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)",-,GO:0006397//mRNA processing,"GO:0016814//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines;GO:0008270//zinc ion binding",K01500//Microbial metabolism in diverse environments;Atrazine degradation
403315,0,0,0,0,0,18,0,0,20,150,0,0,"FAM92A1P2;family with sequence similarity 92, member A3",-,-,-,K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways;K14443//RNA degradation
403323,0,126,0,140,340,0,0,121,49,0,158,0,LOC403323;uncharacterized LOC403323,-,-,-,-
403339,0,0,0,0,0,46,0,0,0,0,0,0,"DEFB133;defensin, beta 133",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
403340,152,47,0,0,0,29,0,0,160,113,12,17,MGC70870;C-terminal binding protein 2 pseudogene,-,-,-,K04496//Notch signaling pathway;Pathways in cancer;Chronic myeloid leukemia;Wnt signaling pathway
403341,0,68,1,0,39,0,26,1,42,0,0,0,ZBTB34;zinc finger and BTB domain containing 34,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
4034,0,18,0,0,22,0,27,0,8,0,0,167,LRCH4;leucine-rich repeats and calponin homology (CH) domain containing 4,GO:0016605//PML body,GO:0007399//nervous system development,GO:0005515//protein binding,K10130//NF-kappa B signaling pathway;p53 signaling pathway
4035,117,0,19,1,0,40,133,60,159,187,7,1,LRP1;low density lipoprotein receptor-related protein 1,GO:0005765//lysosomal membrane;GO:0043025//neuronal cell body;GO:0005905//coated pit;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030136//clathrin-coated vesicle;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0030666//endocytic vesicle membrane;GO:0005925//focal adhesion,"GO:0008203//cholesterol metabolic process;GO:0043277//apoptotic cell clearance;GO:0032956//regulation of actin cytoskeleton organization;GO:0014912//negative regulation of smooth muscle cell migration;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0007603//phototransduction, visible light;GO:0008283//cell proliferation;GO:0032429//regulation of phospholipase A2 activity;GO:0042953//lipoprotein transport;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0001523//retinoid metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0051222//positive regulation of protein transport;GO:0030178//negative regulation of Wnt signaling pathway;GO:0032374//regulation of cholesterol transport;GO:0042157//lipoprotein metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0007568//aging;GO:0043524//negative regulation of neuron apoptotic process;GO:0097242//beta-amyloid clearance;GO:0035909//aorta morphogenesis",GO:0032403//protein complex binding;GO:0004872//receptor activity;GO:0042954//lipoprotein transporter activity;GO:0070325//lipoprotein particle receptor binding;GO:0002020//protease binding;GO:0034185//apolipoprotein binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K04550//Malaria;Alzheimer's disease
4036,256,0,0,0,0,75,66,27,94,199,34,0,LRP2;low density lipoprotein receptor-related protein 2,GO:0005764//lysosome;GO:0043235//receptor complex;GO:0030139//endocytic vesicle;GO:0005905//coated pit;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005768//endosome;GO:0031526//brush border membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0006486//protein glycosylation;GO:0042359//vitamin D metabolic process;GO:0006629//lipid metabolic process;GO:0001523//retinoid metabolic process;GO:0030900//forebrain development;GO:0006897//endocytosis;GO:0008202//steroid metabolic process;GO:0007603//phototransduction, visible light;GO:0008283//cell proliferation;GO:0006898//receptor-mediated endocytosis",GO:0017124//SH3 domain binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K06233//Hedgehog signaling pathway
4037,0,0,0,0,2,0,20,0,26,0,37,0,LRP3;low density lipoprotein receptor-related protein 3,GO:0016021//integral component of membrane;GO:0005905//coated pit,GO:0006898//receptor-mediated endocytosis,-,K04550//Malaria;Alzheimer's disease
4038,0,0,0,0,0,0,46,68,52,0,3,0,LRP4;low density lipoprotein receptor-related protein 4,GO:0016600//flotillin complex;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097060//synaptic membrane;GO:0043025//neuronal cell body;GO:0014069//postsynaptic density,GO:1901631//positive regulation of presynaptic membrane organization;GO:0001932//regulation of protein phosphorylation;GO:0050808//synapse organization;GO:0050771//negative regulation of axonogenesis;GO:0051290//protein heterotetramerization;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0048813//dendrite morphogenesis;GO:0097105//presynaptic membrane assembly;GO:0042733//embryonic digit morphogenesis;GO:0001822//kidney development;GO:0001942//hair follicle development;GO:0060173//limb development;GO:0030198//extracellular matrix organization;GO:0030279//negative regulation of ossification;GO:0006897//endocytosis;GO:0016055//Wnt signaling pathway;GO:0097104//postsynaptic membrane assembly;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009954//proximal/distal pattern formation;GO:0051124//synaptic growth at neuromuscular junction,GO:0030971//receptor tyrosine kinase binding;GO:0097110//scaffold protein binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K03068//Wnt signaling pathway
4040,0,0,0,0,5,32,18,0,17,225,0,0,LRP6;low density lipoprotein receptor-related protein 6,GO:0043235//receptor complex;GO:0005901//caveola;GO:0031410//cytoplasmic vesicle;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0045202//synapse,"GO:0061310//canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0014029//neural crest formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007268//synaptic transmission;GO:0044335//canonical Wnt signaling pathway involved in neural crest cell differentiation;GO:2000168//negative regulation of planar cell polarity pathway involved in neural tube closure;GO:0043065//positive regulation of apoptotic process;GO:0045778//positive regulation of ossification;GO:2000162//negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis;GO:2000164//negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis;GO:0060535//trachea cartilage morphogenesis;GO:0009880//embryonic pattern specification;GO:0060325//face morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0071397//cellular response to cholesterol;GO:0021587//cerebellum morphogenesis;GO:0048596//embryonic camera-type eye morphogenesis;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0016055//Wnt signaling pathway;GO:0001702//gastrulation with mouth forming second;GO:0001843//neural tube closure;GO:0045787//positive regulation of cell cycle;GO:0042475//odontogenesis of dentin-containing tooth;GO:0021861//forebrain radial glial cell differentiation;GO:0051593//response to folic acid;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0044340//canonical Wnt signaling pathway involved in regulation of cell proliferation;GO:0071542//dopaminergic neuron differentiation;GO:0021874//Wnt signaling pathway involved in forebrain neuroblast division;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0030326//embryonic limb morphogenesis;GO:0016337//single organismal cell-cell adhesion;GO:0060021//palate development;GO:0090118//receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0090245//axis elongation involved in somitogenesis;GO:0030901//midbrain development;GO:0021794//thalamus development;GO:0003344//pericardium morphogenesis;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0043434//response to peptide hormone;GO:0021795//cerebral cortex cell migration;GO:0030278//regulation of ossification;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0061324//canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation;GO:0006469//negative regulation of protein kinase activity;GO:0090009//primitive streak formation;GO:2000055//positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0035261//external genitalia morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:1901998//toxin transport;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0045599//negative regulation of fat cell differentiation;GO:0014033//neural crest cell differentiation;GO:2000151//negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0001947//heart looping;GO:2000149//negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis;GO:0060596//mammary placode formation;GO:0060026//convergent extension;GO:0042074//cell migration involved in gastrulation;GO:0009952//anterior/posterior pattern specification;GO:0046849//bone remodeling;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060349//bone morphogenesis;GO:0021987//cerebral cortex development;GO:0035115//embryonic forelimb morphogenesis;GO:0045780//positive regulation of bone resorption;GO:0030917//midbrain-hindbrain boundary development;GO:0021943//formation of radial glial scaffolds;GO:2000166//negative regulation of planar cell polarity pathway involved in pericardium morphogenesis;GO:0036342//post-anal tail morphogenesis;GO:0035116//embryonic hindlimb morphogenesis;GO:0045598//regulation of fat cell differentiation;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0060284//regulation of cell development;GO:0001933//negative regulation of protein phosphorylation",GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0071936//coreceptor activity involved in Wnt signaling pathway;GO:0005041//low-density lipoprotein receptor activity;GO:0005102//receptor binding;GO:0034185//apolipoprotein binding;GO:0019210//kinase inhibitor activity;GO:0042802//identical protein binding;GO:0017147//Wnt-protein binding;GO:0019534//toxin transporter activity;GO:0042813//Wnt-activated receptor activity;GO:0005109//frizzled binding,K03068//Wnt signaling pathway
404037,0,0,0,0,0,10,11,0,16,0,0,0,HAPLN4;hyaluronan and proteoglycan link protein 4,GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion,GO:0005540//hyaluronic acid binding,-
404093,0,40,0,1,0,0,13,93,16,0,0,0,CUEDC1;CUE domain containing 1,-,-,-,-
4041,0,0,0,0,7,13,38,47,10,90,3,0,LRP5;low density lipoprotein receptor-related protein 5,GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,"GO:1902262//apoptotic process involved in patterning of blood vessels;GO:0008284//positive regulation of cell proliferation;GO:0030326//embryonic limb morphogenesis;GO:0035426//extracellular matrix-cell signaling;GO:0048539//bone marrow development;GO:0033690//positive regulation of osteoblast proliferation;GO:0042074//cell migration involved in gastrulation;GO:0061304//retinal blood vessel morphogenesis;GO:0016055//Wnt signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0001702//gastrulation with mouth forming second;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0048596//embryonic camera-type eye morphogenesis;GO:0035019//somatic stem cell maintenance;GO:0009952//anterior/posterior pattern specification;GO:0006007//glucose catabolic process;GO:0046849//bone remodeling;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0002076//osteoblast development;GO:0045840//positive regulation of mitosis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0042632//cholesterol homeostasis;GO:0060349//bone morphogenesis;GO:0006897//endocytosis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0060033//anatomical structure regression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0046850//regulation of bone remodeling;GO:0060612//adipose tissue development;GO:0008203//cholesterol metabolic process;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0060042//retina morphogenesis in camera-type eye;GO:0042733//embryonic digit morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0042981//regulation of apoptotic process;GO:0060764//cell-cell signaling involved in mammary gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0043434//response to peptide hormone;GO:0045668//negative regulation of osteoblast differentiation;GO:0008217//regulation of blood pressure;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus",GO:0019534//toxin transporter activity;GO:0042813//Wnt-activated receptor activity;GO:0015026//coreceptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding,K03068//Wnt signaling pathway
404203,2,0,0,0,0,0,0,0,0,0,0,0,"SPINK6;serine peptidase inhibitor, Kazal type 6",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,-
404217,0,0,0,0,0,0,0,0,0,0,20,0,CTXN1;cortexin 1,GO:0016021//integral component of membrane,-,-,-
404220,0,441,304,738,908,0,43,347,73,126,1402,3,C6orf201;chromosome 6 open reading frame 201,-,-,-,K13239//Peroxisome;Fatty acid metabolism;K08131//Protein digestion and absorption
404281,0,0,0,0,0,19,22,0,23,0,0,0,YY2;YY2 transcription factor,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
4043,0,0,0,0,0,33,29,0,24,0,13,0,LRPAP1;low density lipoprotein receptor-related protein associated protein 1,GO:0005886//plasma membrane;GO:0048237//rough endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle,GO:0032091//negative regulation of protein binding;GO:0016192//vesicle-mediated transport;GO:0010916//negative regulation of very-low-density lipoprotein particle clearance;GO:0006457//protein folding;GO:1900116//extracellular negative regulation of signal transduction;GO:1900222//negative regulation of beta-amyloid clearance;GO:0006898//receptor-mediated endocytosis,GO:0050750//low-density lipoprotein particle receptor binding;GO:0035473//lipase binding;GO:0048019//receptor antagonist activity;GO:0051082//unfolded protein binding;GO:0004873//asialoglycoprotein receptor activity;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0005515//protein binding;GO:0008201//heparin binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
4045,0,2,1,14,124,23,0,0,90,0,4,0,LSAMP;limbic system-associated membrane protein,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0007155//cell adhesion;GO:0035641//locomotory exploration behavior;GO:0007399//nervous system development,GO:0005515//protein binding,-
404550,0,0,0,0,0,0,21,0,3,0,0,0,C16orf74;chromosome 16 open reading frame 74,-,-,-,-
404552,0,0,0,0,0,0,0,0,14,0,0,0,"SCGB1D4;secretoglobin, family 1D, member 4",GO:0005576//extracellular region,-,-,-
4046,1,0,0,0,0,5,0,58,50,0,0,0,LSP1;lymphocyte-specific protein 1,GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0006928//cellular component movement;GO:0007165//signal transduction;GO:0006935//chemotaxis;GO:0006968//cellular defense response,GO:0004871//signal transducer activity;GO:0003779//actin binding,K14957//Tuberculosis
404665,0,253,125,48,188,14,0,474,138,206,483,0,CACTIN-AS1;CACTIN antisense RNA 1,-,-,-,-
404672,29,10,0,19,68,59,6,0,12,0,0,0,"GTF2H5;general transcription factor IIH, polypeptide 5",GO:0005730//nucleolus;GO:0000439//core TFIIH complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0071480//cellular response to gamma radiation;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006294//nucleotide-excision repair, preincision complex assembly;GO:0006289//nucleotide-excision repair;GO:0006364//rRNA processing",GO:0000182//rDNA binding,K10845//Basal transcription factors;Nucleotide excision repair
4047,0,33,0,20,47,57,50,5,42,0,21,0,"LSS;lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)",GO:0016020//membrane;GO:0005811//lipid particle;GO:0005789//endoplasmic reticulum membrane,GO:0008202//steroid metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process,GO:0000250//lanosterol synthase activity,K01852//Biosynthesis of secondary metabolites;Metabolic pathways;Steroid biosynthesis
404785,2,39,92,84,173,9,13,0,8,0,21,0,"POTEG;POTE ankyrin domain family, member G",-,-,-,-
4048,0,33,1,48,195,8,0,82,51,1,0,0,LTA4H;leukotriene A4 hydrolase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006508//proteolysis;GO:0019370//leukotriene biosynthetic process;GO:0006691//leukotriene metabolic process;GO:0006954//inflammatory response;GO:0019369//arachidonic acid metabolic process;GO:0043171//peptide catabolic process,GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0004463//leukotriene-A4 hydrolase activity;GO:0004301//epoxide hydrolase activity;GO:0008233//peptidase activity,K01254//Arachidonic acid metabolism;Metabolic pathways
4049,0,0,0,0,0,11,0,0,0,0,0,0,LTA;lymphotoxin alpha,GO:0005615//extracellular space;GO:0016020//membrane,GO:0044130//negative regulation of growth of symbiont in host;GO:0007267//cell-cell signaling;GO:0032729//positive regulation of interferon-gamma production;GO:0042493//response to drug;GO:0032496//response to lipopolysaccharide;GO:0002876//positive regulation of chronic inflammatory response to antigenic stimulus;GO:0050830//defense response to Gram-positive bacterium;GO:0007165//signal transduction;GO:0006959//humoral immune response;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0007584//response to nutrient;GO:0048535//lymph node development;GO:0043065//positive regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation,GO:0005102//receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity,K05468//HTLV-I infection;Cytokine-cytokine receptor interaction;NF-kappa B signaling pathway;Herpes simplex infection;Type I diabetes mellitus
405,107,55,1,7,58,27,0,0,0,0,14,0,ARNT;aryl hydrocarbon receptor nuclear translocator,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0001666//response to hypoxia;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001892//embryonic placenta development;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045821//positive regulation of glycolytic process;GO:0001938//positive regulation of endothelial cell proliferation;GO:0046886//positive regulation of hormone biosynthetic process;GO:0033235//positive regulation of protein sumoylation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0043619//regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0004874//aryl hydrocarbon receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0035326//enhancer binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0017162//aryl hydrocarbon receptor binding,K09097//Pathways in cancer;Renal cell carcinoma
4051,7,0,0,0,0,14,0,13,4,0,0,0,"CYP4F3;cytochrome P450, family 4, subfamily F, polypeptide 3",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006691//leukotriene metabolic process;GO:0036101//leukotriene B4 catabolic process,GO:0005506//iron ion binding;GO:0052871//alpha-tocopherol omega-hydroxylase activity;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0020037//heme binding;GO:0004497//monooxygenase activity,K00490//Metabolic pathways;Arachidonic acid metabolism
4052,0,0,1,0,0,0,73,0,20,171,2,210,LTBP1;latent transforming growth factor beta binding protein 1,GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0035583//sequestering of TGFbeta in extracellular matrix;GO:0030198//extracellular matrix organization,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0050431//transforming growth factor beta binding;GO:0005024//transforming growth factor beta-activated receptor activity,K08023//TGF-beta signaling pathway
4053,225,0,55,10,86,79,59,0,121,124,28,0,LTBP2;latent transforming growth factor beta binding protein 2,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0009306//protein secretion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006605//protein targeting,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0019838//growth factor binding,K08023//TGF-beta signaling pathway
4054,0,315,94,224,389,15,37,476,176,239,316,2,LTBP3;latent transforming growth factor beta binding protein 3,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031012//extracellular matrix,GO:0036363//transforming growth factor beta activation;GO:0045780//positive regulation of bone resorption;GO:0060349//bone morphogenesis;GO:0046849//bone remodeling;GO:1902462//positive regulation of mesenchymal stem cell proliferation;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0060430//lung saccule development;GO:0030502//negative regulation of bone mineralization;GO:0030198//extracellular matrix organization;GO:0032331//negative regulation of chondrocyte differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway,GO:0005509//calcium ion binding;GO:0050431//transforming growth factor beta binding,K08023//TGF-beta signaling pathway
4055,3,17,0,2,3,0,2,0,23,2,1,0,"LTBR;lymphotoxin beta receptor (TNFR superfamily, member 3)",GO:0016021//integral component of membrane,GO:0016032//viral process;GO:0006915//apoptotic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0046330//positive regulation of JNK cascade,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding,K03159//Intestinal immune network for IgA production;NF-kappa B signaling pathway;HTLV-I infection;Cytokine-cytokine receptor interaction
4056,0,0,0,0,0,0,0,0,8,0,0,0,LTC4S;leukotriene C4 synthase,GO:0005635//nuclear envelope;GO:0005640//nuclear outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0006691//leukotriene metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0019372//lipoxygenase pathway;GO:2001300//lipoxin metabolic process;GO:0043085//positive regulation of catalytic activity,GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0004464//leukotriene-C4 synthase activity;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0005515//protein binding,K00807//Metabolic pathways;Arachidonic acid metabolism
4057,0,0,0,0,0,30,16,0,0,0,0,0,LTF;lactotransferrin,GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0097013//phagocytic vesicle lumen;GO:0042581//specific granule;GO:0005634//nucleus,"GO:0001895//retina homeostasis;GO:0060349//bone morphogenesis;GO:0001817//regulation of cytokine production;GO:0006959//humoral immune response;GO:2001205//negative regulation of osteoclast development;GO:0006508//proteolysis;GO:0033214//iron assimilation by chelation and transport;GO:0090382//phagosome maturation;GO:0051701//interaction with host;GO:0032680//regulation of tumor necrosis factor production;GO:2000308//negative regulation of tumor necrosis factor (ligand) superfamily member 11 production;GO:0052572//response to host immune response;GO:0033690//positive regulation of osteoblast proliferation;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0019731//antibacterial humoral response;GO:0006351//transcription, DNA-templated;GO:0006826//iron ion transport;GO:1902732//positive regulation of chondrocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:1900159//positive regulation of bone mineralization involved in bone maturation;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0001503//ossification;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0002227//innate immune response in mucosa;GO:1900229//negative regulation of single-species biofilm formation in or on host organism;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0019732//antifungal humoral response;GO:0045669//positive regulation of osteoblast differentiation",GO:0043539//protein serine/threonine kinase activator activity;GO:0003677//DNA binding;GO:0004252//serine-type endopeptidase activity;GO:0008201//heparin binding;GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0005506//iron ion binding,K14736//Mineral absorption
405753,0,0,7,23,31,11,0,0,26,0,9,11,DUOXA2;dual oxidase maturation factor 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0042743//hydrogen peroxide metabolic process;GO:0015031//protein transport;GO:0050727//regulation of inflammatory response,-,-
405754,51,0,0,0,0,0,0,0,13,0,0,0,"ERVFRD-1;endogenous retrovirus group FRD, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0019031//viral envelope,GO:0006949//syncytium formation,-,K04257//Olfactory transduction;K13962//Gastric acid secretion
4058,0,0,0,0,0,9,4,0,0,149,0,0,LTK;leukocyte receptor tyrosine kinase,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0071300//cellular response to retinoic acid;GO:0008283//cell proliferation,GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding,-
4059,77,0,0,0,6,0,10,0,34,0,1,0,BCAM;basal cell adhesion molecule (Lutheran blood group),GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion,GO:0004888//transmembrane signaling receptor activity;GO:0043236//laminin binding;GO:0005055//laminin receptor activity,-
4060,0,0,0,0,0,1,0,0,21,0,0,0,LUM;lumican,GO:0005583//fibrillar collagen trimer;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0031012//extracellular matrix,GO:0070848//response to growth factor;GO:0042340//keratan sulfate catabolic process;GO:0030199//collagen fibril organization;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0051216//cartilage development;GO:0007601//visual perception;GO:0030198//extracellular matrix organization;GO:0018146//keratan sulfate biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0005975//carbohydrate metabolic process;GO:0014070//response to organic cyclic compound,GO:0005518//collagen binding;GO:0005201//extracellular matrix structural constituent,-
4061,69,0,0,0,0,11,0,0,0,0,0,0,"LY6E;lymphocyte antigen 6 complex, locus E",GO:0005887//integral component of plasma membrane;GO:0031225//anchored component of membrane,GO:0035265//organ growth;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0030325//adrenal gland development;GO:0048242//epinephrine secretion;GO:0001701//in utero embryonic development;GO:0042415//norepinephrine metabolic process;GO:0007166//cell surface receptor signaling pathway,-,-
4062,0,0,0,0,0,0,0,0,7,0,0,0,"LY6H;lymphocyte antigen 6 complex, locus H",GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0009887//organ morphogenesis;GO:0007399//nervous system development,-,-
4063,0,0,0,0,7,0,0,0,35,3,13,0,LY9;lymphocyte antigen 9,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0004872//receptor activity,-
4064,0,0,0,0,0,0,18,56,0,0,0,0,CD180;CD180 molecule,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0002322//B cell proliferation involved in immune response;GO:0045087//innate immune response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0006954//inflammatory response;GO:0071222//cellular response to lipopolysaccharide,-,-
4065,0,0,0,0,0,0,44,0,0,0,0,0,LY75;lymphocyte antigen 75,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0006955//immune response;GO:0006954//inflammatory response;GO:0006897//endocytosis,GO:0004872//receptor activity;GO:0030246//carbohydrate binding,-
4066,0,0,0,0,0,0,0,2,0,0,0,0,LYL1;lymphoblastic leukemia associated hematopoiesis regulator 1,GO:0005634//nucleus,"GO:0001955//blood vessel maturation;GO:0006355//regulation of transcription, DNA-templated;GO:0060216//definitive hemopoiesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030183//B cell differentiation",GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0005515//protein binding,K15604//Transcriptional misregulation in cancer
4067,0,27,0,0,11,0,23,0,47,49,0,0,"LYN;LYN proto-oncogene, Src family tyrosine kinase",GO:0005794//Golgi apparatus;GO:0005758//mitochondrial intermembrane space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0034666//integrin alpha2-beta1 complex;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0042629//mast cell granule;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030061//mitochondrial crista,GO:0002553//histamine secretion by mast cell;GO:0034605//cellular response to heat;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0045087//innate immune response;GO:0070667//negative regulation of mast cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:0070447//positive regulation of oligodendrocyte progenitor proliferation;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0070304//positive regulation of stress-activated protein kinase signaling cascade;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0016032//viral process;GO:0014070//response to organic cyclic compound;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:0002576//platelet degranulation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0071300//cellular response to retinoic acid;GO:0007596//blood coagulation;GO:0050853//B cell receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030218//erythrocyte differentiation;GO:0042493//response to drug;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0050663//cytokine secretion;GO:0002768//immune response-regulating cell surface receptor signaling pathway;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0009725//response to hormone;GO:0007165//signal transduction;GO:0050777//negative regulation of immune response;GO:0033003//regulation of mast cell activation;GO:0046777//protein autophosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0042531//positive regulation of tyrosine phosphorylation of STAT protein;GO:0009743//response to carbohydrate;GO:0006468//protein phosphorylation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0001782//B cell homeostasis;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006991//response to sterol depletion;GO:0043407//negative regulation of MAP kinase activity;GO:0050855//regulation of B cell receptor signaling pathway;GO:0043200//response to amino acid;GO:0060252//positive regulation of glial cell proliferation;GO:0009636//response to toxic substance;GO:0045646//regulation of erythrocyte differentiation;GO:0002431//Fc receptor mediated stimulatory signaling pathway;GO:0060369//positive regulation of Fc receptor mediated stimulatory signaling pathway;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0090025//regulation of monocyte chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0001933//negative regulation of protein phosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0002902//regulation of B cell apoptotic process;GO:0023014//signal transduction by phosphorylation;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0030168//platelet activation;GO:0070668//positive regulation of mast cell proliferation;GO:0048678//response to axon injury;GO:0031668//cellular response to extracellular stimulus;GO:0001817//regulation of cytokine production;GO:0043304//regulation of mast cell degranulation;GO:0032868//response to insulin;GO:0031175//neuron projection development;GO:0097028//dendritic cell differentiation;GO:0031295//T cell costimulation;GO:0002513//tolerance induction to self antigen;GO:0002774//Fc receptor mediated inhibitory signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0050727//regulation of inflammatory response;GO:0050900//leukocyte migration;GO:0010976//positive regulation of neuron projection development;GO:0030889//negative regulation of B cell proliferation;GO:0014003//oligodendrocyte development;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0050707//regulation of cytokine secretion;GO:0090330//regulation of platelet aggregation,GO:0043208//glycosphingolipid binding;GO:0017124//SH3 domain binding;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0019899//enzyme binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0051219//phosphoprotein binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0044325//ion channel binding;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity,K05854//Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;B cell receptor signaling pathway;Fc gamma R-mediated phagocytosis;Long-term depression;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Chemokine signaling pathway
4068,0,0,0,0,0,0,42,0,6,0,0,0,SH2D1A;SH2 domain containing 1A,GO:0005737//cytoplasm,GO:0009967//positive regulation of signal transduction;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0006959//humoral immune response;GO:0007267//cell-cell signaling;GO:0006968//cellular defense response,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07990//Measles;Natural killer cell mediated cytotoxicity
406893,0,0,0,0,0,0,0,0,17,0,0,0,MIR101-1;microRNA 101-1,-,-,-,-
406894,0,0,0,0,0,19,0,0,0,0,0,0,MIR101-2;microRNA 101-2,-,-,-,-
406900,0,0,0,0,12,0,0,0,0,0,0,0,MIR106B;microRNA 106b,-,-,-,-
406918,0,0,0,0,0,0,0,0,25,0,0,0,MIR129-2;microRNA 129-2,-,-,-,-
406925,84,0,0,0,0,0,0,0,0,0,0,0,MIR135A1;microRNA 135a-1,-,-,-,-
406934,0,0,0,0,0,0,0,0,15,0,0,0,MIR142;microRNA 142,-,-,-,-
406940,0,0,0,0,0,0,0,0,0,185,0,1,MIR148A;microRNA 148a,-,-,-,-
406946,112,0,0,0,0,0,0,0,0,0,0,0,MIR154;microRNA 154,-,-,-,-
406950,0,0,0,0,0,0,0,0,0,0,5,0,MIR16-1;microRNA 16-1,-,-,-,-
406951,0,0,0,0,0,0,0,0,9,0,0,0,MIR16-2;microRNA 16-2,-,-,-,-
406954,0,0,0,0,0,0,2,0,0,0,0,0,MIR181A2;microRNA 181a-2,-,-,-,-
406959,0,0,0,0,0,0,0,0,0,0,0,69,MIR183;microRNA 183,-,-,-,-
406960,0,0,0,0,0,0,0,0,0,0,15,0,MIR184;microRNA 184,-,-,-,-
406964,83,0,0,0,0,0,0,0,0,0,0,0,MIR188;microRNA 188,-,-,-,-
406966,0,0,0,0,0,0,0,0,1,0,0,0,MIR191;microRNA 191,-,-,-,-
406972,0,0,0,0,0,0,0,0,13,0,0,0,MIR196A1;microRNA 196a-1,-,-,-,-
406978,0,0,0,0,0,0,0,0,0,0,0,2,MIR199B;microRNA 199b,-,-,-,-
406983,0,0,0,0,0,0,0,0,0,0,7,0,MIR200A;microRNA 200a,-,-,-,-
406986,0,0,0,0,0,0,0,0,20,0,0,0,MIR203A;microRNA 203a,-,-,-,-
406991,0,0,0,0,0,9,0,0,0,0,0,0,MIR21;microRNA 21,-,-,-,-
406995,52,0,0,0,0,0,0,0,0,0,0,0,MIR181A1;microRNA 181a-1,-,-,-,-
406998,0,0,0,0,0,0,0,0,14,0,0,0,MIR216A;microRNA 216a,-,-,-,-
407,0,0,52,0,10,0,0,0,28,245,0,0,"ARR3;arrestin 3, retinal (X-arrestin)",GO:0045202//synapse;GO:0005737//cytoplasm;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment,GO:0006897//endocytosis;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0001932//regulation of protein phosphorylation,GO:0002046//opsin binding;GO:0005515//protein binding;GO:0051219//phosphoprotein binding,-
4070,91,0,0,3,27,0,0,106,11,0,4,0,TACSTD2;tumor-associated calcium signal transducer 2,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0016328//lateral plasma membrane;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus,GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:1900028//negative regulation of ruffle assembly;GO:0010633//negative regulation of epithelial cell migration;GO:0008283//cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0050678//regulation of epithelial cell proliferation;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:0007601//visual perception;GO:0060675//ureteric bud morphogenesis;GO:2000146//negative regulation of cell motility;GO:2000738//positive regulation of stem cell differentiation;GO:0051497//negative regulation of stress fiber assembly,GO:0005515//protein binding;GO:0004872//receptor activity,-
407002,0,0,0,0,0,0,0,0,0,0,0,33,MIR219A1;microRNA 219a-1,-,-,-,-
407006,0,0,0,0,0,0,0,0,13,0,0,0,MIR221;microRNA 221,-,-,-,-
407007,0,0,0,0,0,0,0,0,21,0,0,0,MIR222;microRNA 222,-,-,-,-
407009,69,0,0,0,0,0,5,0,0,0,0,0,MIR224;microRNA 224,-,-,-,-
407014,0,0,47,0,0,0,0,0,25,0,0,0,MIR25;microRNA 25,-,-,-,-
407017,0,0,0,0,0,0,0,0,15,0,0,0,MIR26B;microRNA 26b,-,-,-,-
407020,98,0,0,0,0,0,0,0,0,0,0,0,MIR28;microRNA 28,-,-,-,-
407030,0,0,0,0,0,0,0,0,9,0,0,0,MIR30B;microRNA 30b,-,-,-,-
407037,0,0,0,0,0,0,0,13,0,0,0,0,MIR320A;microRNA 320a,-,-,-,-
407043,0,0,0,0,0,0,0,0,26,0,0,0,MIR7-1;microRNA 7-1,-,-,-,-
407046,2,0,0,0,0,0,0,0,0,0,0,0,MIR9-1;microRNA 9-1,-,-,-,-
407050,0,0,0,6,0,0,0,0,0,0,0,0,MIR93;microRNA 93,-,-,-,-
407051,95,0,0,0,0,0,0,0,0,0,0,0,MIR9-3;microRNA 9-3,-,-,-,-
407053,0,0,0,0,0,10,0,0,7,0,0,0,MIR96;microRNA 96,-,-,-,-
407054,0,0,0,0,0,0,0,0,1,0,0,0,MIR98;microRNA 98,-,-,-,-
407056,0,0,0,0,0,0,0,36,0,0,0,0,MIR99B;microRNA 99b,-,-,-,-
4071,0,0,0,0,36,11,0,31,1,0,0,0,TM4SF1;transmembrane 4 L six family member 1,GO:0005887//integral component of plasma membrane,-,-,-
4072,0,0,0,18,0,12,0,0,7,0,15,0,EPCAM;epithelial cell adhesion molecule,GO:0005923//tight junction;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016328//lateral plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0023019//signal transduction involved in regulation of gene expression;GO:0001657//ureteric bud development;GO:0048863//stem cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000648//positive regulation of stem cell proliferation,GO:0032403//protein complex binding;GO:0005515//protein binding,-
4074,0,119,95,145,270,0,0,41,7,0,182,0,M6PR;mannose-6-phosphate receptor (cation dependent),GO:0005770//late endosome;GO:0016020//membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005765//lysosomal membrane,GO:0006898//receptor-mediated endocytosis;GO:0008333//endosome to lysosome transport;GO:0015761//mannose transport;GO:0007165//signal transduction,GO:0005537//mannose binding;GO:0004888//transmembrane signaling receptor activity;GO:0015578//mannose transmembrane transporter activity,K10089//Lysosome;Phagosome
4076,0,94,1,50,544,23,0,0,24,0,19,0,CAPRIN1;cell cycle associated protein 1,GO:0030425//dendrite;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0010494//cytoplasmic stress granule;GO:0005887//integral component of plasma membrane,GO:0050775//positive regulation of dendrite morphogenesis;GO:0017148//negative regulation of translation;GO:0061003//positive regulation of dendritic spine morphogenesis,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding,-
4077,0,108,57,116,463,0,20,0,33,0,1,0,NBR1;neighbor of BRCA1 gene 1,GO:0000407//pre-autophagosomal structure;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005770//late endosome;GO:0031410//cytoplasmic vesicle;GO:0005829//cytosol;GO:0031430//M band;GO:0005776//autophagic vacuole;GO:0005764//lysosome,GO:0016236//macroautophagy;GO:0051259//protein oligomerization;GO:0045668//negative regulation of osteoblast differentiation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0030500//regulation of bone mineralization,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0051019//mitogen-activated protein kinase binding;GO:0043130//ubiquitin binding,K14381//Osteoclast differentiation
407738,0,0,0,0,0,0,35,0,0,0,0,0,"FAM19A1;family with sequence similarity 19 (chemokine (C-C motif)-like), member A1",GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region,-,-,-
408,8,96,3,7,23,10,15,150,34,1,22,0,"ARRB1;arrestin, beta 1",GO:0005829//cytosol;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0045211//postsynaptic membrane;GO:0005634//nucleus;GO:0000785//chromatin;GO:0016323//basolateral plasma membrane;GO:0031143//pseudopodium;GO:0005765//lysosomal membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0005905//coated pit;GO:0014069//postsynaptic density;GO:0005834//heterotrimeric G-protein complex;GO:0000139//Golgi membrane,GO:0007602//phototransduction;GO:0007596//blood coagulation;GO:0043149//stress fiber assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0030168//platelet activation;GO:0001933//negative regulation of protein phosphorylation;GO:0032092//positive regulation of protein binding;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0035025//positive regulation of Rho protein signal transduction;GO:0035066//positive regulation of histone acetylation;GO:0090240//positive regulation of histone H4 acetylation;GO:0043066//negative regulation of apoptotic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002031//G-protein coupled receptor internalization;GO:0043547//positive regulation of GTPase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006366//transcription from RNA polymerase II promoter;GO:0031397//negative regulation of protein ubiquitination;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0061024//membrane organization;GO:0006309//apoptotic DNA fragmentation;GO:0002092//positive regulation of receptor internalization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032715//negative regulation of interleukin-6 production;GO:0007219//Notch signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0000187//activation of MAPK activity;GO:0006892//post-Golgi vesicle-mediated transport;GO:0034260//negative regulation of GTPase activity;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0045309//protein phosphorylated amino acid binding;GO:0030331//estrogen receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0004402//histone acetyltransferase activity;GO:0005096//GTPase activator activity;GO:0031701//angiotensin receptor binding;GO:0031762//follicle-stimulating hormone receptor binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0031896//V2 vasopressin receptor binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031692//alpha-1B adrenergic receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0035615//clathrin adaptor activity;GO:0004857//enzyme inhibitor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0035612//AP-2 adaptor complex binding;GO:0044325//ion channel binding;GO:0031691//alpha-1A adrenergic receptor binding,K04439//Olfactory transduction;Phototransduction;Morphine addiction;Endocytosis;Dopaminergic synapse;MAPK signaling pathway;Chemokine signaling pathway
408029,54,0,0,0,0,0,0,0,0,0,0,1,C2orf27B;chromosome 2 open reading frame 27B,-,-,-,-
408050,1,0,1,0,0,8,3,0,0,2,0,19,NOMO3;NODAL modulator 3,GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
4081,0,32,1,5,1,0,0,0,5,0,0,0,MAB21L1;mab-21-like 1 (C. elegans),GO:0005634//nucleus,GO:0009653//anatomical structure morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0043010//camera-type eye development,-,-
4082,0,25,1,14,51,7,0,242,30,0,32,0,MARCKS;myristoylated alanine-rich protein kinase C substrate,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005813//centrosome;GO:0005938//cell cortex;GO:0042585//germinal vesicle,GO:0044281//small molecule metabolic process;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion,GO:0005516//calmodulin binding;GO:0051015//actin filament binding;GO:0005080//protein kinase C binding,K12561//Fc gamma R-mediated phagocytosis
408263,0,0,0,0,0,38,1,1,0,259,0,0,FNDC9;fibronectin type III domain containing 9,GO:0016021//integral component of membrane,-,-,-
4084,0,0,0,1,30,23,0,0,47,0,0,0,MXD1;MAX dimerization protein 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003712//transcription cofactor activity;GO:0003714//transcription corepressor activity;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
4085,0,0,0,0,0,0,0,0,38,0,0,0,MAD2L1;MAD2 mitotic arrest deficient-like 1 (yeast),GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0072686//mitotic spindle;GO:0000922//spindle pole;GO:0005643//nuclear pore;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0042177//negative regulation of protein catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0000278//mitotic cell cycle;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0007094//mitotic spindle assembly checkpoint;GO:0000070//mitotic sister chromatid segregation;GO:0060564//negative regulation of mitotic anaphase-promoting complex activity;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007093//mitotic cell cycle checkpoint;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045930//negative regulation of mitotic cell cycle,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding,K02537//Cell cycle - yeast;Progesterone-mediated oocyte maturation;Cell cycle;HTLV-I infection;Oocyte meiosis;Meiosis - yeast
4086,0,0,0,12,36,16,0,54,68,0,10,0,SMAD1;SMAD family member 1,GO:0005637//nuclear inner membrane;GO:0005730//nucleolus;GO:0005622//intracellular;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex,"GO:0051216//cartilage development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0007183//SMAD protein complex assembly;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0060038//cardiac muscle cell proliferation;GO:0050775//positive regulation of dendrite morphogenesis;GO:0001710//mesodermal cell fate commitment;GO:0010656//negative regulation of muscle cell apoptotic process;GO:0030902//hindbrain development;GO:0002051//osteoblast fate commitment;GO:0042493//response to drug;GO:0042592//homeostatic process;GO:0071773//cellular response to BMP stimulus;GO:0045669//positive regulation of osteoblast differentiation;GO:0007276//gamete generation;GO:0000165//MAPK cascade;GO:0031053//primary miRNA processing;GO:0042060//wound healing;GO:0009880//embryonic pattern specification;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0010243//response to organonitrogen compound;GO:0061036//positive regulation of cartilage development;GO:0001657//ureteric bud development;GO:0007165//signal transduction;GO:0060348//bone development;GO:0006468//protein phosphorylation","GO:0070410//co-SMAD binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0005057//receptor signaling protein activity;GO:0070411//I-SMAD binding;GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity",K04676//TGF-beta signaling pathway;Transcriptional misregulation in cancer
4087,95,33,31,132,227,12,23,0,77,0,8,0,SMAD2;SMAD family member 2,GO:0071141//SMAD protein complex;GO:0071144//SMAD2-SMAD3 protein complex;GO:0005737//cytoplasm;GO:0032444//activin responsive factor complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0070723//response to cholesterol;GO:0001657//ureteric bud development;GO:0031053//primary miRNA processing;GO:0001706//endoderm formation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031016//pancreas development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023019//signal transduction involved in regulation of gene expression;GO:0048340//paraxial mesoderm morphogenesis;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001707//mesoderm formation;GO:0001701//in utero embryonic development;GO:0032924//activin receptor signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0060039//pericardium development;GO:0048617//embryonic foregut morphogenesis;GO:0030073//insulin secretion;GO:0009952//anterior/posterior pattern specification;GO:0007183//SMAD protein complex assembly;GO:0007369//gastrulation;GO:0051098//regulation of binding;GO:0048589//developmental growth;GO:0009791//post-embryonic development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0038092//nodal signaling pathway;GO:0007352//zygotic specification of dorsal/ventral axis;GO:0060021//palate development;GO:0010467//gene expression;GO:0007182//common-partner SMAD protein phosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0035265//organ growth;GO:0035556//intracellular signal transduction;GO:0009749//response to glucose;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0007179//transforming growth factor beta receptor signaling pathway","GO:0033613//activating transcription factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0070411//I-SMAD binding;GO:0046332//SMAD binding;GO:0005160//transforming growth factor beta receptor binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0035326//enhancer binding;GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0070412//R-SMAD binding;GO:0008134//transcription factor binding;GO:0070410//co-SMAD binding;GO:0019902//phosphatase binding;GO:0005515//protein binding",K04500//Chronic myeloid leukemia;Wnt signaling pathway;Cell cycle;Colorectal cancer;Adherens junction;HTLV-I infection;Pancreatic cancer;Endocytosis;Chagas disease (American trypanosomiasis);Pathways in cancer;TGF-beta signaling pathway
4088,0,2,0,5,123,13,19,2,61,0,11,0,SMAD3;SMAD family member 3,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0071141//SMAD protein complex;GO:0071144//SMAD2-SMAD3 protein complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex;GO:0043235//receptor complex;GO:0005637//nuclear inner membrane;GO:0005829//cytosol,"GO:0001707//mesoderm formation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045216//cell-cell junction organization;GO:0032332//positive regulation of chondrocyte differentiation;GO:0032924//activin receptor signaling pathway;GO:0031053//primary miRNA processing;GO:0042060//wound healing;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0051894//positive regulation of focal adhesion assembly;GO:0030335//positive regulation of cell migration;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023019//signal transduction involved in regulation of gene expression;GO:0009880//embryonic pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0001666//response to hypoxia;GO:0042177//negative regulation of protein catabolic process;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0050927//positive regulation of positive chemotaxis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0038092//nodal signaling pathway;GO:0060039//pericardium development;GO:0050776//regulation of immune response;GO:0048617//embryonic foregut morphogenesis;GO:0007183//SMAD protein complex assembly;GO:0030501//positive regulation of bone mineralization;GO:0033689//negative regulation of osteoblast proliferation;GO:0006810//transport;GO:0019049//evasion or tolerance of host defenses by virus;GO:0016202//regulation of striated muscle tissue development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0032731//positive regulation of interleukin-1 beta production;GO:0001756//somitogenesis;GO:0001947//heart looping;GO:0050821//protein stabilization;GO:0002520//immune system development;GO:0061045//negative regulation of wound healing;GO:0048340//paraxial mesoderm morphogenesis;GO:0007492//endoderm development;GO:0030878//thyroid gland development;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0001657//ureteric bud development;GO:0050678//regulation of epithelial cell proliferation;GO:0045668//negative regulation of osteoblast differentiation;GO:0032916//positive regulation of transforming growth factor beta3 production;GO:0045930//negative regulation of mitotic cell cycle;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0001889//liver development;GO:0001933//negative regulation of protein phosphorylation;GO:0006955//immune response;GO:0035413//positive regulation of catenin import into nucleus;GO:1901313//positive regulation of gene expression involved in extracellular matrix organization;GO:0060290//transdifferentiation;GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0030308//negative regulation of cell growth;GO:0070306//lens fiber cell differentiation;GO:0035556//intracellular signal transduction;GO:0051098//regulation of binding;GO:0007050//cell cycle arrest;GO:0048589//developmental growth;GO:0032909//regulation of transforming growth factor beta2 production;GO:0002076//osteoblast development;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway","GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0070410//co-SMAD binding;GO:0019902//phosphatase binding;GO:0008270//zinc ion binding;GO:0043130//ubiquitin binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0019901//protein kinase binding;GO:0000988//protein binding transcription factor activity;GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0070412//R-SMAD binding;GO:0035326//enhancer binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005518//collagen binding;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0008013//beta-catenin binding;GO:0043425//bHLH transcription factor binding;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0005160//transforming growth factor beta receptor binding",K04500//TGF-beta signaling pathway;Pathways in cancer;Chagas disease (American trypanosomiasis);Pancreatic cancer;Endocytosis;HTLV-I infection;Adherens junction;Colorectal cancer;Cell cycle;Wnt signaling pathway;Chronic myeloid leukemia
4089,0,42,3,93,267,23,29,73,65,153,0,0,SMAD4;SMAD family member 4,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0032444//activin responsive factor complex;GO:0005654//nucleoplasm;GO:0071141//SMAD protein complex,"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0003251//positive regulation of cell proliferation involved in heart valve morphogenesis;GO:0042118//endothelial cell activation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048663//neuron fate commitment;GO:0071559//response to transforming growth factor beta;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0042177//negative regulation of protein catabolic process;GO:0001666//response to hypoxia;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003279//cardiac septum development;GO:0001701//in utero embryonic development;GO:0072134//nephrogenic mesenchyme morphogenesis;GO:0072133//metanephric mesenchyme morphogenesis;GO:0060395//SMAD protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007492//endoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014033//neural crest cell differentiation;GO:0007498//mesoderm development;GO:0007411//axon guidance;GO:0036302//atrioventricular canal development;GO:0001702//gastrulation with mouth forming second;GO:0048589//developmental growth;GO:0032909//regulation of transforming growth factor beta2 production;GO:0051098//regulation of binding;GO:0060956//endocardial cell differentiation;GO:0007183//SMAD protein complex assembly;GO:0030513//positive regulation of BMP signaling pathway;GO:0060548//negative regulation of cell death;GO:0048733//sebaceous gland development;GO:0051797//regulation of hair follicle development;GO:0048859//formation of anatomical boundary;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0003360//brainstem development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0032525//somite rostral/caudal axis specification;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0035556//intracellular signal transduction;GO:0030308//negative regulation of cell growth;GO:0003190//atrioventricular valve formation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0060021//palate development;GO:0030509//BMP signaling pathway;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter","GO:0005515//protein binding;GO:0070412//R-SMAD binding;GO:0003682//chromatin binding;GO:0042802//identical protein binding;GO:0000988//protein binding transcription factor activity;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0005518//collagen binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0070411//I-SMAD binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0030616//transforming growth factor beta receptor, common-partner cytoplasmic mediator activity",K04501//Wnt signaling pathway;Chronic myeloid leukemia;Colorectal cancer;Cell cycle;Adherens junction;Pancreatic cancer;HTLV-I infection;Pathways in cancer;TGF-beta signaling pathway
409,0,0,0,0,1,1,0,1,22,0,0,0,"ARRB2;arrestin, beta 2",GO:0005905//coated pit;GO:0014069//postsynaptic density;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane,"GO:0051928//positive regulation of calcium ion transport;GO:0032695//negative regulation of interleukin-12 production;GO:0034392//negative regulation of smooth muscle cell apoptotic process;GO:0007420//brain development;GO:0002031//G-protein coupled receptor internalization;GO:0051897//positive regulation of protein kinase B signaling;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0060326//cell chemotaxis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007596//blood coagulation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0042699//follicle-stimulating hormone signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0030168//platelet activation;GO:0045953//negative regulation of natural killer cell mediated cytotoxicity;GO:0031623//receptor internalization;GO:0060765//regulation of androgen receptor signaling pathway;GO:0032691//negative regulation of interleukin-1 beta production;GO:0034260//negative regulation of GTPase activity;GO:2000573//positive regulation of DNA biosynthetic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0007628//adult walking behavior;GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0002032//desensitization of G-protein coupled receptor protein signaling pathway by arrestin;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0002092//positive regulation of receptor internalization;GO:0043065//positive regulation of apoptotic process;GO:0031397//negative regulation of protein ubiquitination;GO:0006309//apoptotic DNA fragmentation;GO:0032715//negative regulation of interleukin-6 production;GO:0007219//Notch signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity",GO:0043422//protein kinase B binding;GO:0031691//alpha-1A adrenergic receptor binding;GO:0032947//protein complex scaffold;GO:0001664//G-protein coupled receptor binding;GO:0071889//14-3-3 protein binding;GO:0005102//receptor binding;GO:0031692//alpha-1B adrenergic receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0031702//type 1 angiotensin receptor binding;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0031762//follicle-stimulating hormone receptor binding;GO:0031701//angiotensin receptor binding;GO:0031748//D1 dopamine receptor binding;GO:0031826//type 2A serotonin receptor binding;GO:0019904//protein domain specific binding;GO:0051019//mitogen-activated protein kinase binding;GO:0019899//enzyme binding,K04439//Olfactory transduction;Endocytosis;Morphine addiction;Phototransduction;Dopaminergic synapse;MAPK signaling pathway;Chemokine signaling pathway
4090,50,2,0,28,110,27,0,0,29,0,0,0,SMAD5;SMAD family member 5,GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005622//intracellular,"GO:0002051//osteoblast fate commitment;GO:0060348//bone development;GO:0006468//protein phosphorylation;GO:0001880//Mullerian duct regression;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0007165//signal transduction;GO:0001657//ureteric bud development;GO:0006351//transcription, DNA-templated;GO:0030509//BMP signaling pathway;GO:0071407//cellular response to organic cyclic compound;GO:0035556//intracellular signal transduction;GO:0009880//embryonic pattern specification;GO:0060048//cardiac muscle contraction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030218//erythrocyte differentiation;GO:0007281//germ cell development;GO:0051216//cartilage development;GO:0071773//cellular response to BMP stimulus;GO:0045669//positive regulation of osteoblast differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway","GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005057//receptor signaling protein activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding",K04676//Transcriptional misregulation in cancer;TGF-beta signaling pathway
4091,0,0,0,0,2,11,0,0,8,0,0,0,SMAD6;SMAD family member 6,GO:0005829//cytosol;GO:0043234//protein complex;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045444//fat cell differentiation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0031589//cell-substrate adhesion;GO:0001657//ureteric bud development;GO:0030514//negative regulation of BMP signaling pathway;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0043627//response to estrogen;GO:0034616//response to laminar fluid shear stress;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006955//immune response;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0007352//zygotic specification of dorsal/ventral axis;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0030509//BMP signaling pathway","GO:0030617//transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity;GO:0070698//type I activin receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0070410//co-SMAD binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding;GO:0031625//ubiquitin protein ligase binding",K04677//Endocytosis;TGF-beta signaling pathway
4092,0,0,0,0,21,0,23,0,16,0,6,0,SMAD7;SMAD family member 7,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0016342//catenin complex;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005913//cell-cell adherens junction;GO:0005737//cytoplasm;GO:0005886//plasma membrane,"GO:0050821//protein stabilization;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0034629//cellular protein complex localization;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0031397//negative regulation of protein ubiquitination;GO:0030514//negative regulation of BMP signaling pathway;GO:0001657//ureteric bud development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0010467//gene expression;GO:0030509//BMP signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0035556//intracellular signal transduction;GO:0030336//negative regulation of cell migration;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032925//regulation of activin receptor signaling pathway;GO:0034333//adherens junction assembly;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0055117//regulation of cardiac muscle contraction;GO:0034616//response to laminar fluid shear stress;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0022409//positive regulation of cell-cell adhesion;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0048844//artery morphogenesis;GO:0031398//positive regulation of protein ubiquitination;GO:0060412//ventricular septum morphogenesis;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation","GO:0031625//ubiquitin protein ligase binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0070411//I-SMAD binding;GO:0008013//beta-catenin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0048185//activin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0030617//transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity;GO:0044212//transcription regulatory region DNA binding;GO:0005518//collagen binding",K04677//TGF-beta signaling pathway;Endocytosis
4093,0,0,1,40,104,14,22,0,32,145,0,0,SMAD9;SMAD family member 9,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005622//intracellular;GO:0005829//cytosol,"GO:0071407//cellular response to organic cyclic compound;GO:0060348//bone development;GO:0030509//BMP signaling pathway;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0001666//response to hypoxia;GO:0006351//transcription, DNA-templated;GO:0045597//positive regulation of cell differentiation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051216//cartilage development;GO:0001657//ureteric bud development;GO:0030902//hindbrain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030901//midbrain development;GO:0001880//Mullerian duct regression","GO:0030618//transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding",K04676//Transcriptional misregulation in cancer;TGF-beta signaling pathway
4094,0,16,1,75,357,0,0,0,19,129,1,0,MAF;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000785//chromatin,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048468//cell development;GO:0032330//regulation of chondrocyte differentiation;GO:0048839//inner ear development;GO:0006366//transcription from RNA polymerase II promoter;GO:0070306//lens fiber cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001816//cytokine production,GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09035//Transcriptional misregulation in cancer
4097,71,0,0,0,1,0,0,52,13,148,12,0,MAFG;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G,GO:0005654//nucleoplasm,"GO:0007596//blood coagulation;GO:0030534//adult behavior;GO:0006351//transcription, DNA-templated;GO:0030641//regulation of cellular pH;GO:0042127//regulation of cell proliferation;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0045604//regulation of epidermal cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
4099,0,0,0,0,0,0,12,0,34,166,0,375,MAG;myelin associated glycoprotein,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043220//Schmidt-Lanterman incisure;GO:0033270//paranode region of axon,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007596//blood coagulation;GO:0050771//negative regulation of axonogenesis;GO:0050900//leukocyte migration;GO:0021762//substantia nigra development;GO:0050770//regulation of axonogenesis;GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,K06771//Cell adhesion molecules (CAMs)
41,95,0,0,0,0,20,1,0,21,0,0,0,ASIC1;acid-sensing (proton-gated) ion channel 1,GO:0005886//plasma membrane;GO:0045202//synapse;GO:0005887//integral component of plasma membrane,GO:0008306//associative learning;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0042391//regulation of membrane potential;GO:0010447//response to acidic pH;GO:0009268//response to pH;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0070207//protein homotrimerization;GO:0050915//sensory perception of sour taste;GO:0070588//calcium ion transmembrane transport;GO:0006814//sodium ion transport;GO:0071467//cellular response to pH;GO:0046929//negative regulation of neurotransmitter secretion;GO:0007165//signal transduction;GO:0007613//memory,GO:0044736//acid-sensing ion channel activity;GO:0005515//protein binding;GO:0022839//ion gated channel activity;GO:0015280//ligand-gated sodium channel activity,-
410,0,0,0,0,1,11,0,0,51,0,0,0,ARSA;arylsulfatase A,GO:0005788//endoplasmic reticulum lumen;GO:0005764//lysosome;GO:0005615//extracellular space;GO:0001669//acrosomal vesicle;GO:0031232//extrinsic component of external side of plasma membrane;GO:0043202//lysosomal lumen;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0051597//response to methylmercury;GO:0043687//post-translational protein modification;GO:0007339//binding of sperm to zona pellucida;GO:0009268//response to pH;GO:0045471//response to ethanol;GO:0043627//response to estrogen;GO:0007417//central nervous system development;GO:0044267//cellular protein metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006914//autophagy;GO:0007584//response to nutrient;GO:0006665//sphingolipid metabolic process,GO:0008484//sulfuric ester hydrolase activity;GO:0004098//cerebroside-sulfatase activity;GO:0005509//calcium ion binding;GO:0004065//arylsulfatase activity,K01134//Lysosome;Sphingolipid metabolism
4100,0,0,0,0,0,10,0,0,0,0,0,0,"MAGEA1;melanoma antigen family A, 1 (directs expression of antigen MZ2-E)",GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045746//negative regulation of Notch signaling pathway;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0042826//histone deacetylase binding,K12464//Neurotrophin signaling pathway
4101,0,0,0,0,0,15,0,0,0,0,0,0,"MAGEA2;melanoma antigen family A, 2",-,-,-,K12464//Neurotrophin signaling pathway
4102,0,0,0,0,0,0,0,0,11,0,0,0,"MAGEA3;melanoma antigen family A, 3",-,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
4103,0,0,0,0,0,12,0,0,24,0,0,0,"MAGEA4;melanoma antigen family A, 4",-,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
4107,0,0,0,0,16,0,0,0,12,0,0,0,"MAGEA8;melanoma antigen family A, 8",-,-,-,K12464//Neurotrophin signaling pathway
4109,0,0,0,0,0,7,0,0,11,88,0,0,"MAGEA10;melanoma antigen family A, 10",GO:0005634//nucleus,-,-,K12464//Neurotrophin signaling pathway
411,0,36,0,43,32,36,0,0,51,0,10,0,ARSB;arylsulfatase B,GO:0005764//lysosome;GO:0043202//lysosomal lumen;GO:0005788//endoplasmic reticulum lumen;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005791//rough endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0007041//lysosomal transport;GO:0044281//small molecule metabolic process;GO:0009268//response to pH;GO:0007417//central nervous system development;GO:0030204//chondroitin sulfate metabolic process;GO:0007040//lysosome organization;GO:0030203//glycosaminoglycan metabolic process;GO:0051597//response to methylmercury;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0043687//post-translational protein modification;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0043627//response to estrogen;GO:0006665//sphingolipid metabolic process;GO:0007584//response to nutrient;GO:0006914//autophagy,GO:0003943//N-acetylgalactosamine-4-sulfatase activity;GO:0004065//arylsulfatase activity;GO:0046872//metal ion binding,K01135//Lysosome;Metabolic pathways;Glycosaminoglycan degradation
4110,0,0,0,0,0,0,10,0,23,142,6,0,"MAGEA11;melanoma antigen family A, 11",GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
4111,0,0,0,0,0,17,0,0,15,0,0,0,"MAGEA12;melanoma antigen family A, 12",-,-,-,K12464//Neurotrophin signaling pathway
4112,0,0,0,0,0,0,13,0,24,0,0,0,"MAGEB1;melanoma antigen family B, 1",-,-,-,K12464//Neurotrophin signaling pathway
4114,0,0,0,0,0,9,0,0,18,0,0,0,"MAGEB3;melanoma antigen family B, 3",-,-,-,K12464//Neurotrophin signaling pathway
4115,0,0,0,0,0,0,0,0,45,0,1,629,"MAGEB4;melanoma antigen family B, 4",-,-,-,K12464//Neurotrophin signaling pathway
4116,0,0,0,16,27,0,0,0,40,0,0,0,"MAGOH;mago-nashi homolog, proliferation-associated (Drosophila)",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035145//exon-exon junction complex;GO:0005829//cytosol;GO:0071013//catalytic step 2 spliceosome;GO:0016607//nuclear speck,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006417//regulation of translation;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031124//mRNA 3'-end processing;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006406//mRNA export from nucleus",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12877//Spliceosome;RNA transport;mRNA surveillance pathway
4117,0,97,0,39,24,13,21,135,15,92,48,0,MAK;male germ cell-associated kinase,GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030496//midbody;GO:0072686//mitotic spindle,"GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0051726//regulation of cell cycle;GO:0045494//photoreceptor cell maintenance;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0030154//cell differentiation",GO:0003713//transcription coactivator activity;GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,-
4118,0,0,0,0,0,13,0,0,0,270,5,0,"MAL;mal, T-cell differentiation protein",GO:0005768//endosome;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0005887//integral component of plasma membrane,GO:0030154//cell differentiation;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0045176//apical protein localization;GO:0042552//myelination;GO:0006915//apoptotic process;GO:0055085//transmembrane transport;GO:0001766//membrane raft polarization;GO:0007417//central nervous system development,GO:0005515//protein binding;GO:0015267//channel activity;GO:0016505//peptidase activator activity involved in apoptotic process;GO:0019911//structural constituent of myelin sheath;GO:0008289//lipid binding,-
412,67,1,0,15,1,0,0,0,0,0,10,0,"STS;steroid sulfatase (microsomal), isozyme S",GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005764//lysosome;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0043231//intracellular membrane-bounded organelle,GO:0044281//small molecule metabolic process;GO:0043687//post-translational protein modification;GO:0007565//female pregnancy;GO:0044267//cellular protein metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0008544//epidermis development;GO:0006706//steroid catabolic process;GO:0006665//sphingolipid metabolic process,GO:0008484//sulfuric ester hydrolase activity;GO:0004773//steryl-sulfatase activity;GO:0046872//metal ion binding,K01131//Steroid hormone biosynthesis
4121,0,0,0,0,0,0,0,0,14,0,0,0,"MAN1A1;mannosidase, alpha, class 1A, member 1",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding",K01230//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
4122,190,0,0,0,0,28,30,0,18,0,0,1,"MAN2A2;mannosidase, alpha, class 2A, member 2",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006013//mannose metabolic process,"GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds;GO:0008270//zinc ion binding;GO:0030246//carbohydrate binding;GO:0004572//mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity",K01231//N-Glycan biosynthesis;Metabolic pathways
4123,5,154,22,12,93,25,71,269,25,0,86,0,"MAN2C1;mannosidase, alpha, class 2C, member 1",-,GO:0006013//mannose metabolic process,GO:0004559//alpha-mannosidase activity;GO:0030246//carbohydrate binding;GO:0008270//zinc ion binding,K01191//Cyanoamino acid metabolism;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Pyrimidine metabolism;Sphingolipid metabolism;Galactose metabolism;Metabolic pathways;Glycerolipid metabolism;Other glycan degradation
4124,0,8,0,0,9,0,29,103,70,0,16,0,"MAN2A1;mannosidase, alpha, class 2A, member 1",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005801//cis-Golgi network;GO:0070062//extracellular vesicular exosome,GO:0018279//protein N-linked glycosylation via asparagine;GO:0050769//positive regulation of neurogenesis;GO:0048286//lung alveolus development;GO:0007005//mitochondrion organization;GO:0006013//mannose metabolic process;GO:0001889//liver development;GO:0006491//N-glycan processing;GO:0007585//respiratory gaseous exchange;GO:0001701//in utero embryonic development;GO:0007033//vacuole organization;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0060042//retina morphogenesis in camera-type eye,"GO:0030246//carbohydrate binding;GO:0004572//mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity;GO:0008270//zinc ion binding;GO:0016799//hydrolase activity, hydrolyzing N-glycosyl compounds",K01231//Metabolic pathways;N-Glycan biosynthesis
4125,0,0,1,0,26,0,0,0,27,0,8,0,"MAN2B1;mannosidase, alpha, class 2B, member 1",GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,GO:0006013//mannose metabolic process;GO:0006517//protein deglycosylation;GO:0006464//cellular protein modification process,GO:0004559//alpha-mannosidase activity;GO:0008270//zinc ion binding;GO:0030246//carbohydrate binding,K12311//Lysosome;Other glycan degradation
4126,0,0,0,0,0,29,0,0,2,0,0,0,"MANBA;mannosidase, beta A, lysosomal",GO:0043231//intracellular membrane-bounded organelle;GO:0005764//lysosome,GO:0006464//cellular protein modification process;GO:0006516//glycoprotein catabolic process;GO:0046355//mannan catabolic process,GO:0005537//mannose binding;GO:0004567//beta-mannosidase activity,K01192//Lysosome;Other glycan degradation
4128,0,139,1,97,148,19,21,0,65,109,7,0,MAOA;monoamine oxidase A,GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0007268//synaptic transmission;GO:0042420//dopamine catabolic process;GO:0042135//neurotransmitter catabolic process;GO:0007269//neurotransmitter secretion;GO:0042136//neurotransmitter biosynthetic process;GO:0006576//cellular biogenic amine metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0008131//primary amine oxidase activity,"K00274//Glycine, serine and threonine metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites;Serotonergic synapse;Alcoholism;Histidine metabolism;Dopaminergic synapse;Cocaine addiction;Isoquinoline alkaloid biosynthesis;Phenylalanine metabolism;Arginine and proline metabolism;Tyrosine metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Amphetamine addiction"
4129,0,0,0,0,0,30,0,0,41,0,0,0,MAOB;monoamine oxidase B,GO:0005740//mitochondrial envelope;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane,GO:0045471//response to ethanol;GO:0010044//response to aluminum ion;GO:0010269//response to selenium ion;GO:0051412//response to corticosterone;GO:0055114//oxidation-reduction process;GO:0014063//negative regulation of serotonin secretion;GO:0032496//response to lipopolysaccharide;GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0006805//xenobiotic metabolic process;GO:0009636//response to toxic substance;GO:0045964//positive regulation of dopamine metabolic process;GO:0042493//response to drug,GO:0009055//electron carrier activity;GO:0042803//protein homodimerization activity;GO:0008131//primary amine oxidase activity;GO:0050660//flavin adenine dinucleotide binding,"K00274//Histidine metabolism;Isoquinoline alkaloid biosynthesis;Dopaminergic synapse;Cocaine addiction;Tryptophan metabolism;Glycine, serine and threonine metabolism;Serotonergic synapse;Alcoholism;Biosynthesis of secondary metabolites;Drug metabolism - cytochrome P450;Metabolic pathways;Tyrosine metabolism;Amphetamine addiction;Phenylalanine metabolism;Arginine and proline metabolism"
4130,43,0,0,0,0,42,53,133,76,0,8,0,MAP1A;microtubule-associated protein 1A,GO:0005874//microtubule;GO:0005829//cytosol;GO:0005875//microtubule associated complex,GO:0000226//microtubule cytoskeleton organization;GO:0007605//sensory perception of sound,GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0005198//structural molecule activity,-
4131,1,0,0,1,4,23,18,109,53,0,11,0,MAP1B;microtubule-associated protein 1B,GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0005874//microtubule;GO:0005829//cytosol;GO:0005875//microtubule associated complex,GO:0048675//axon extension;GO:0009987//cellular process;GO:0001578//microtubule bundle formation;GO:0032387//negative regulation of intracellular transport;GO:0045773//positive regulation of axon extension;GO:0047497//mitochondrion transport along microtubule;GO:0016358//dendrite development;GO:0061162//establishment of monopolar cell polarity,GO:0005198//structural molecule activity;GO:0008017//microtubule binding;GO:0005515//protein binding,-
4133,0,0,22,13,37,14,15,0,63,0,0,0,MAP2;microtubule-associated protein 2,GO:0005874//microtubule;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0034399//nuclear periphery;GO:0005875//microtubule associated complex;GO:0043198//dendritic shaft,GO:0031175//neuron projection development;GO:0007409//axonogenesis;GO:0071310//cellular response to organic substance;GO:0021954//central nervous system neuron development;GO:0001578//microtubule bundle formation;GO:0048813//dendrite morphogenesis,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0002162//dystroglycan binding;GO:0005198//structural molecule activity;GO:0005516//calmodulin binding,-
4134,0,36,0,45,86,15,1,0,60,0,0,0,MAP4;microtubule-associated protein 4,GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005875//microtubule associated complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0072686//mitotic spindle,GO:0051012//microtubule sliding;GO:0051301//cell division;GO:0007052//mitotic spindle organization;GO:0051294//establishment of spindle orientation,GO:0005198//structural molecule activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
4135,248,1,54,11,53,7,17,318,6,0,29,0,MAP6;microtubule-associated protein 6,GO:0005794//Golgi apparatus;GO:0048471//perinuclear region of cytoplasm;GO:0005874//microtubule,GO:0032418//lysosome localization;GO:0000226//microtubule cytoskeleton organization;GO:0006810//transport;GO:0048813//dendrite morphogenesis,GO:0005516//calmodulin binding;GO:0008017//microtubule binding;GO:0005515//protein binding,-
4137,80,0,0,0,11,0,69,0,19,0,0,0,MAPT;microtubule-associated protein tau,GO:0005886//plasma membrane;GO:0030426//growth cone;GO:0030424//axon;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0034399//nuclear periphery;GO:0005930//axoneme;GO:0005874//microtubule;GO:0045298//tubulin complex,GO:0048699//generation of neurons;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0010506//regulation of autophagy;GO:0031116//positive regulation of microtubule polymerization;GO:0060632//regulation of microtubule-based movement;GO:0045773//positive regulation of axon extension;GO:0000226//microtubule cytoskeleton organization;GO:0032387//negative regulation of intracellular transport;GO:0008088//axon cargo transport;GO:0007628//adult walking behavior;GO:0047497//mitochondrion transport along microtubule;GO:0006915//apoptotic process;GO:0048675//axon extension;GO:0001764//neuron migration,GO:0005515//protein binding;GO:0071813//lipoprotein particle binding;GO:0034185//apolipoprotein binding;GO:0019901//protein kinase binding;GO:0008017//microtubule binding;GO:0017124//SH3 domain binding;GO:0019899//enzyme binding;GO:0005200//structural constituent of cytoskeleton,K04380//Alzheimer's disease;MAPK signaling pathway
4139,0,0,0,0,4,24,31,2,29,0,0,0,MARK1;MAP/microtubule affinity-regulating kinase 1,GO:0015630//microtubule cytoskeleton;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0035556//intracellular signal transduction;GO:0016055//Wnt signaling pathway;GO:0007010//cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0001764//neuron migration,"GO:0004674//protein serine/threonine kinase activity;GO:0050321//tau-protein kinase activity;GO:0001786//phosphatidylserine binding;GO:0000287//magnesium ion binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005524//ATP binding;GO:0070300//phosphatidic acid binding",-
414,0,0,0,0,0,0,0,0,74,0,3,0,ARSD;arylsulfatase D,GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005764//lysosome,GO:0006665//sphingolipid metabolic process;GO:0043687//post-translational protein modification;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0004065//arylsulfatase activity,-
4140,0,0,0,0,81,0,0,0,27,0,0,0,MARK3;MAP/microtubule affinity-regulating kinase 3,GO:0005886//plasma membrane,GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
414059,0,0,0,0,0,0,2,1,13,0,0,0,"TBC1D3B;TBC1 domain family, member 3B",GO:0005886//plasma membrane,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,-
414060,15,0,0,0,0,0,0,0,0,0,15,0,"TBC1D3C;TBC1 domain family, member 3C",GO:0005886//plasma membrane,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,-
414061,0,0,0,0,0,11,1,0,21,0,0,0,"DNAJB3;DnaJ (Hsp40) homolog, subfamily B, member 3",GO:0070062//extracellular vesicular exosome,-,-,-
4141,0,1,1,28,33,16,0,0,45,0,0,0,MARS;methionyl-tRNA synthetase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006418//tRNA aminoacylation for protein translation;GO:0006431//methionyl-tRNA aminoacylation;GO:0010467//gene expression,GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0004825//methionine-tRNA ligase activity,K01874//Selenocompound metabolism;Base excision repair;Aminoacyl-tRNA biosynthesis
414149,103,0,0,8,0,18,0,0,0,0,0,0,ACBD7;acyl-CoA binding domain containing 7,-,-,GO:0000062//fatty-acyl-CoA binding;GO:0008289//lipid binding,K08762//PPAR signaling pathway
414152,9,0,0,0,0,14,30,26,4,73,11,0,C10orf105;chromosome 10 open reading frame 105,GO:0016021//integral component of membrane,-,-,-
414157,0,0,2,0,2,7,0,0,0,0,0,0,C10orf62;chromosome 10 open reading frame 62,-,-,GO:0005515//protein binding,-
414189,0,0,0,0,1,13,0,0,3,1,0,0,"AGAP6;ArfGAP with GTPase domain, ankyrin repeat and PH domain 6",-,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12491//Endocytosis
414194,0,0,24,0,0,0,0,0,0,154,0,0,CCNYL2;cyclin Y-like 2,-,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding,K04237//Endocytosis;Tight junction;Chemokine signaling pathway;Neuroactive ligand-receptor interaction;Adherens junction
4142,0,0,0,0,0,0,0,0,0,120,0,0,"MAS1;MAS1 proto-oncogene, G protein-coupled receptor",GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:0038166//angiotensin-activated signaling pathway;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0045740//positive regulation of DNA replication;GO:0071375//cellular response to peptide hormone stimulus;GO:0007186//G-protein coupled receptor signaling pathway;GO:0014823//response to activity;GO:0050727//regulation of inflammatory response;GO:0034698//response to gonadotropin;GO:0070528//protein kinase C signaling;GO:0008283//cell proliferation;GO:0009653//anatomical structure morphogenesis;GO:0001933//negative regulation of protein phosphorylation;GO:0021766//hippocampus development;GO:0042493//response to drug;GO:0008284//positive regulation of cell proliferation,GO:0042277//peptide binding;GO:0004930//G-protein coupled receptor activity;GO:0017046//peptide hormone binding;GO:0004945//angiotensin type II receptor activity,K04303//Neuroactive ligand-receptor interaction;Renin-angiotensin system
414224,0,0,0,0,0,1,16,0,21,0,0,0,"CTGLF12P;centaurin, gamma-like family, member 12 pseudogene",-,-,-,K12491//Endocytosis
414235,0,0,0,0,0,0,34,0,49,0,0,0,PRR26;proline rich 26,-,-,-,-
414236,0,0,0,0,0,0,0,10,0,0,0,0,C10orf55;chromosome 10 open reading frame 55,-,-,-,K01348//Complement and coagulation cascades;Transcriptional misregulation in cancer;NF-kappa B signaling pathway
414241,0,0,0,0,1,21,0,0,16,0,0,0,"FAM35BP;family with sequence similarity 35, member A pseudogene",-,-,-,-
414245,0,0,56,38,8,10,0,0,13,0,0,0,DNAJC9-AS1;DNAJC9 antisense RNA 1,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
4143,0,0,0,0,0,0,28,0,15,0,0,0,"MAT1A;methionine adenosyltransferase I, alpha",GO:0005829//cytosol,GO:0006730//one-carbon metabolic process;GO:0032259//methylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006556//S-adenosylmethionine biosynthetic process;GO:0006520//cellular amino acid metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004478//methionine adenosyltransferase activity,K00789//Metabolic pathways;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites
414301,0,0,0,0,0,0,0,86,0,124,0,0,DDI1;DNA-damage inducible 1 homolog 1 (S. cerevisiae),-,GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity,-
414318,0,0,0,0,0,36,0,0,0,0,1,0,C9orf106;chromosome 9 open reading frame 106,-,-,-,-
414328,83,0,0,0,24,14,0,0,25,0,0,0,"IDNK;idnK, gluconokinase homolog (E. coli)",-,GO:0016310//phosphorylation;GO:0046177//D-gluconate catabolic process,GO:0005524//ATP binding;GO:0046316//gluconokinase activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00851//Metabolic pathways;Pentose phosphate pathway;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
414332,0,0,0,0,0,0,24,0,14,0,1,0,LCN10;lipocalin 10,GO:0005576//extracellular region,GO:0006810//transport,-,-
4144,0,0,8,83,176,37,0,66,36,0,22,313,"MAT2A;methionine adenosyltransferase II, alpha",GO:0048269//methionine adenosyltransferase complex;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0032259//methylation;GO:0000096//sulfur amino acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006556//S-adenosylmethionine biosynthetic process;GO:0006730//one-carbon metabolic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004478//methionine adenosyltransferase activity,K00789//Biosynthesis of secondary metabolites;Cysteine and methionine metabolism;Metabolic pathways
4145,72,0,0,0,0,9,0,0,0,0,34,0,MATK;megakaryocyte-associated tyrosine kinase,GO:0005829//cytosol;GO:0016020//membrane,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation;GO:0007498//mesoderm development;GO:0008284//positive regulation of cell proliferation;GO:0008283//cell proliferation,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding,K08888//Neurotrophin signaling pathway
4146,0,26,0,0,0,0,35,56,61,0,45,0,"MATN1;matrilin 1, cartilage matrix protein",GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030500//regulation of bone mineralization;GO:0030198//extracellular matrix organization;GO:0003429//growth plate cartilage chondrocyte morphogenesis;GO:0006461//protein complex assembly,GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
4147,0,0,0,0,0,42,0,83,1,4,0,0,MATN2;matrilin 2,GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,-,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
414765,0,0,0,0,0,0,0,0,2,0,0,0,HCG25;HLA complex group 25 (non-protein coding),-,-,-,-
4148,0,0,0,0,0,0,0,0,2,0,0,0,MATN3;matrilin 3,GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development,GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent,K08133//Protein digestion and absorption
414899,0,0,0,0,0,0,0,0,36,0,0,0,"BLID;BH3-like motif containing, cell death inducer",GO:0005739//mitochondrion,GO:0006915//apoptotic process,-,-
4149,100,161,0,66,355,0,0,6,0,0,20,0,MAX;MYC associated factor X,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0071339//MLL1 complex;GO:0005730//nucleolus;GO:0030425//dendrite;GO:0016605//PML body,"GO:0048678//response to axon injury;GO:0051402//neuron apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0009267//cellular response to starvation;GO:0032868//response to insulin;GO:0060041//retina development in camera-type eye;GO:0006461//protein complex assembly;GO:0010629//negative regulation of gene expression;GO:0071375//cellular response to peptide hormone stimulus",GO:0043565//sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0032403//protein complex binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity,K04453//Transcriptional misregulation in cancer;Small cell lung cancer;MAPK signaling pathway;Pathways in cancer
414918,1,0,0,0,0,0,26,0,5,0,5,0,DENND6B;DENN/MADD domain containing 6B,GO:0055037//recycling endosome,GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,-
414919,0,14,2,0,9,0,0,0,0,0,1,0,C8orf82;chromosome 8 open reading frame 82,-,-,-,-
414927,0,0,0,0,0,0,37,0,17,0,0,0,"MGC34796;sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene",-,-,-,K00072//Metabolic pathways;Folate biosynthesis
415,0,0,0,0,0,6,0,0,22,0,26,0,ARSE;arylsulfatase E (chondrodysplasia punctata 1),GO:0005788//endoplasmic reticulum lumen;GO:0005795//Golgi stack;GO:0070062//extracellular vesicular exosome,GO:0006665//sphingolipid metabolic process;GO:0043687//post-translational protein modification;GO:0001501//skeletal system development;GO:0044267//cellular protein metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044281//small molecule metabolic process,GO:0004065//arylsulfatase activity;GO:0046872//metal ion binding,-
4150,0,100,68,106,703,5,47,1,0,0,13,0,MAZ;MYC-associated zinc finger protein (purine-binding transcription factor),GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006369//termination of RNA polymerase II transcription,GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003682//chromatin binding,-
4151,79,14,0,8,2,0,40,0,51,0,0,0,MB;myoglobin,GO:0070062//extracellular vesicular exosome,GO:0042542//response to hydrogen peroxide;GO:0015671//oxygen transport;GO:0050873//brown fat cell differentiation;GO:0001666//response to hypoxia;GO:0043353//enucleate erythrocyte differentiation;GO:0007507//heart development;GO:0031444//slow-twitch skeletal muscle fiber contraction;GO:0009725//response to hormone,GO:0005506//iron ion binding;GO:0005344//oxygen transporter activity;GO:0020037//heme binding;GO:0019825//oxygen binding,-
415116,0,0,0,0,0,0,0,96,13,0,3,0,"PIM3;Pim-3 proto-oncogene, serine/threonine kinase",GO:0005737//cytoplasm,GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0046777//protein autophosphorylation;GO:0007049//cell cycle;GO:0016572//histone phosphorylation;GO:0007346//regulation of mitotic cell cycle,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
415117,0,0,0,0,0,0,0,0,0,0,10,0,STX19;syntaxin 19,GO:0016021//integral component of membrane,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,GO:0005515//protein binding;GO:0005484//SNAP receptor activity,K08487//SNARE interactions in vesicular transport
4152,0,1,1,0,23,0,0,1,19,0,19,0,MBD1;methyl-CpG binding domain protein 1,GO:0016607//nuclear speck;GO:0000792//heterochromatin;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008327//methyl-CpG binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
4153,0,0,0,0,0,0,27,23,19,0,4,0,"MBL2;mannose-binding lectin (protein C) 2, soluble",GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005581//collagen trimer,"GO:0006956//complement activation;GO:0006953//acute-phase response;GO:0042742//defense response to bacterium;GO:0006979//response to oxidative stress;GO:0006958//complement activation, classical pathway;GO:0008228//opsonization;GO:0050830//defense response to Gram-positive bacterium;GO:0048525//negative regulation of viral process;GO:0044130//negative regulation of growth of symbiont in host;GO:0045087//innate immune response;GO:0050766//positive regulation of phagocytosis;GO:0051873//killing by host of symbiont cells;GO:0001867//complement activation, lectin pathway",GO:0005102//receptor binding;GO:0048306//calcium-dependent protein binding;GO:0005537//mannose binding;GO:0005515//protein binding,K03991//Complement and coagulation cascades;Phagosome;Staphylococcus aureus infection
4154,0,63,0,71,97,5,13,28,10,0,115,0,MBNL1;muscleblind-like splicing regulator 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus,"GO:0007519//skeletal muscle tissue development;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006376//mRNA splice site selection;GO:0030326//embryonic limb morphogenesis;GO:0043484//regulation of RNA splicing;GO:0001701//in utero embryonic development;GO:0045445//myoblast differentiation",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003725//double-stranded RNA binding;GO:0003723//RNA binding,-
4155,0,2,78,17,70,2,20,29,35,0,6,0,MBP;myelin basic protein,GO:0043218//compact myelin;GO:0005886//plasma membrane;GO:0033269//internode region of axon;GO:0043025//neuronal cell body;GO:0005634//nucleus,GO:0006955//immune response;GO:0042552//myelination;GO:0050771//negative regulation of axonogenesis;GO:0061024//membrane organization;GO:0007268//synaptic transmission;GO:0007417//central nervous system development;GO:0008366//axon ensheathment;GO:0021762//substantia nigra development;GO:0009636//response to toxic substance,GO:0002020//protease binding;GO:0005515//protein binding;GO:0019911//structural constituent of myelin sheath,-
4157,0,0,18,0,0,0,0,61,17,0,18,307,MC1R;melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0032720//negative regulation of tumor necrosis factor production;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0070914//UV-damage excision repair;GO:0035556//intracellular signal transduction;GO:0007275//multicellular organismal development;GO:0051897//positive regulation of protein kinase B signaling;GO:0042438//melanin biosynthetic process;GO:0009650//UV protection;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019233//sensory perception of pain;GO:0090037//positive regulation of protein kinase C signaling;GO:0043473//pigmentation;GO:0010739//positive regulation of protein kinase A signaling",GO:0008528//G-protein coupled peptide receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity;GO:0004977//melanocortin receptor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome;K04199//Melanogenesis;Neuroactive ligand-receptor interaction
4158,0,0,0,0,0,0,21,39,0,0,0,0,MC2R;melanocortin 2 receptor (adrenocorticotropic hormone),GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001890//placenta development;GO:0030819//positive regulation of cAMP biosynthetic process",GO:0004978//corticotropin receptor activity;GO:0005515//protein binding;GO:0004977//melanocortin receptor activity,K04200//Neuroactive ligand-receptor interaction
416,0,0,0,8,0,39,10,0,0,0,0,0,ARSF;arylsulfatase F,GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process,GO:0046872//metal ion binding;GO:0004065//arylsulfatase activity,-
4160,82,0,0,0,0,0,0,0,0,0,0,0,MC4R;melanocortin 4 receptor,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0032868//response to insulin;GO:2000252//negative regulation of feeding behavior;GO:0002024//diet induced thermogenesis;GO:0030073//insulin secretion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0045780//positive regulation of bone resorption;GO:2000821//regulation of grooming behavior;GO:0007631//feeding behavior;GO:0006112//energy reserve metabolic process,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042923//neuropeptide binding;GO:0017046//peptide hormone binding;GO:0004977//melanocortin receptor activity;GO:0004980//melanocyte-stimulating hormone receptor activity,K04202//Neuroactive ligand-receptor interaction
4161,0,0,0,0,0,0,0,0,29,0,0,0,MC5R;melanocortin 5 receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0030819//positive regulation of cAMP biosynthetic process",GO:0005515//protein binding;GO:0004977//melanocortin receptor activity;GO:0042562//hormone binding,K04203//Neuroactive ligand-receptor interaction
4162,0,0,0,0,0,30,0,28,0,0,6,0,MCAM;melanoma cell adhesion molecule,GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0009653//anatomical structure morphogenesis;GO:0003094//glomerular filtration;GO:0061042//vascular wound healing,-,-
4163,0,0,15,9,17,27,42,0,115,32,29,0,MCC;mutated in colorectal cancers,GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0010633//negative regulation of epithelial cell migration;GO:0007165//signal transduction;GO:0050680//negative regulation of epithelial cell proliferation;GO:0016055//Wnt signaling pathway,GO:0004872//receptor activity;GO:0005515//protein binding,K16072//NF-kappa B signaling pathway;K11447//Transcriptional misregulation in cancer;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton
4166,0,0,0,0,4,32,46,0,8,112,0,0,CHST6;carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006790//sulfur compound metabolic process;GO:0018146//keratan sulfate biosynthetic process,GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity,K09671//Glycosaminoglycan biosynthesis - keratan sulfate
4168,0,0,0,0,0,12,15,14,51,0,0,0,MCF2;MCF.2 cell line derived transforming sequence,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton,GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0016358//dendrite development;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
417,0,0,0,0,0,0,2,0,9,0,0,0,ART1;ADP-ribosyltransferase 1,GO:0031225//anchored component of membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface,GO:0045087//innate immune response;GO:0006471//protein ADP-ribosylation,GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
4170,0,32,0,55,176,1,0,0,0,0,1,0,MCL1;myeloid cell leukemia 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm;GO:0005741//mitochondrial outer membrane;GO:0097136//Bcl-2 family protein complex;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0034097//response to cytokine;GO:0001709//cell fate determination;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:2000811//negative regulation of anoikis;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0007275//multicellular organismal development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:2001020//regulation of response to DNA damage stimulus;GO:0008637//apoptotic mitochondrial changes;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0019725//cellular homeostasis;GO:0071806//protein transmembrane transport,GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0015266//protein channel activity;GO:0051434//BH3 domain binding,-
4171,0,0,0,27,0,0,38,0,49,0,13,0,MCM2;minichromosome maintenance complex component 2,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005664//nuclear origin of replication recognition complex;GO:0042555//MCM complex;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0000785//chromatin;GO:0005730//nucleolus,GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006268//DNA unwinding involved in DNA replication;GO:0007049//cell cycle;GO:0006334//nucleosome assembly;GO:0000082//G1/S transition of mitotic cell cycle;GO:0071353//cellular response to interleukin-4,GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0003688//DNA replication origin binding;GO:0003678//DNA helicase activity,K02540//Cell cycle;Cell cycle - yeast;Meiosis - yeast;DNA replication
4172,61,9,0,1,23,10,0,0,67,0,10,0,MCM3;minichromosome maintenance complex component 3,GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm;GO:0005658//alpha DNA polymerase:primase complex;GO:0005634//nucleus;GO:0042555//MCM complex;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005813//centrosome,GO:0032508//DNA duplex unwinding;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0000082//G1/S transition of mitotic cell cycle,GO:0005515//protein binding;GO:0003678//DNA helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding,K02541//Cell cycle - yeast;Cell cycle;DNA replication;Meiosis - yeast
4173,0,29,1,8,6,31,14,0,0,0,1,0,MCM4;minichromosome maintenance complex component 4,GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus;GO:0042555//MCM complex;GO:0005654//nucleoplasm,GO:0006268//DNA unwinding involved in DNA replication;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation,GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding,K02212//Cell cycle - yeast;Cell cycle;DNA replication;Meiosis - yeast
4174,0,0,0,0,4,8,0,0,13,114,6,0,MCM5;minichromosome maintenance complex component 5,GO:0042555//MCM complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0032508//DNA duplex unwinding;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle,GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0005515//protein binding;GO:0003677//DNA binding,K02209//DNA replication;Meiosis - yeast;Cell cycle;Cell cycle - yeast
4175,0,0,0,0,0,9,0,0,49,0,12,0,MCM6;minichromosome maintenance complex component 6,GO:0005654//nucleoplasm;GO:0042555//MCM complex;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006268//DNA unwinding involved in DNA replication,GO:0042802//identical protein binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity,K02542//Meiosis - yeast;DNA replication;Cell cycle;Cell cycle - yeast
4176,0,18,19,46,100,0,19,1,8,0,64,4,MCM7;minichromosome maintenance complex component 7,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0000785//chromatin;GO:0042555//MCM complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0071364//cellular response to epidermal growth factor stimulus;GO:0008283//cell proliferation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006270//DNA replication initiation;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0042325//regulation of phosphorylation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042493//response to drug;GO:0006268//DNA unwinding involved in DNA replication,GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K02210//Cell cycle - yeast;Cell cycle;DNA replication;Meiosis - yeast
4179,0,0,0,14,29,26,0,0,50,0,0,0,"CD46;CD46 molecule, complement regulatory protein",GO:0009986//cell surface;GO:0002079//inner acrosomal membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,"GO:0006508//proteolysis;GO:0035581//sequestering of extracellular ligand from receptor;GO:0007338//single fertilization;GO:0043382//positive regulation of memory T cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0016032//viral process;GO:0010628//positive regulation of gene expression;GO:0008593//regulation of Notch signaling pathway;GO:0006958//complement activation, classical pathway;GO:0002250//adaptive immune response;GO:0045916//negative regulation of complement activation;GO:0032733//positive regulation of interleukin-10 production;GO:0032613//interleukin-10 production;GO:0045591//positive regulation of regulatory T cell differentiation;GO:0002456//T cell mediated immunity;GO:0030449//regulation of complement activation;GO:0010629//negative regulation of gene expression;GO:0071636//positive regulation of transforming growth factor beta production;GO:0045087//innate immune response",GO:0045296//cadherin binding;GO:0005515//protein binding;GO:0001848//complement binding;GO:0004872//receptor activity,K04007//Measles;Complement and coagulation cascades
4184,0,0,70,0,0,0,0,0,0,0,0,0,SMCP;sperm mitochondria-associated cysteine-rich protein,GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005737//cytoplasm,GO:0030317//sperm motility;GO:0007341//penetration of zona pellucida,-,-
4185,0,0,0,0,2,12,41,54,31,0,0,262,ADAM11;ADAM metallopeptidase domain 11,GO:0031012//extracellular matrix;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0007229//integrin-mediated signaling pathway,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0005178//integrin binding;GO:0004222//metalloendopeptidase activity,-
4189,26,50,0,0,0,0,7,68,43,1,0,0,"DNAJB9;DnaJ (Hsp40) homolog, subfamily B, member 9",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0051787//misfolded protein binding,-
4190,0,47,1,51,93,0,54,0,24,0,2,1,"MDH1;malate dehydrogenase 1, NAD (soluble)",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0006734//NADH metabolic process;GO:0006006//glucose metabolic process;GO:0006108//malate metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006094//gluconeogenesis;GO:0044262//cellular carbohydrate metabolic process,GO:0004470//malic enzyme activity;GO:0030060//L-malate dehydrogenase activity;GO:0047860//diiodophenylpyruvate reductase activity;GO:0051287//NAD binding,K00025//Glyoxylate and dicarboxylate metabolism;Pyruvate metabolism;Citrate cycle (TCA cycle);Metabolic pathways;Biosynthesis of secondary metabolites;Proximal tubule bicarbonate reclamation;Carbon fixation in photosynthetic organisms
4191,0,36,22,50,63,57,0,0,53,0,16,0,"MDH2;malate dehydrogenase 2, NAD (mitochondrial)",GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0006099//tricarboxylic acid cycle;GO:0044262//cellular carbohydrate metabolic process;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process;GO:0006108//malate metabolic process;GO:0044237//cellular metabolic process;GO:0006006//glucose metabolic process;GO:0006734//NADH metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006475//internal protein amino acid acetylation,GO:0030060//L-malate dehydrogenase activity;GO:0046554//malate dehydrogenase (NADP+) activity;GO:0044822//poly(A) RNA binding;GO:0043621//protein self-association,K00026//Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Glyoxylate and dicarboxylate metabolism;Pyruvate metabolism;Metabolic pathways;Citrate cycle (TCA cycle)
4192,0,1,0,0,6,0,0,0,0,0,0,0,MDK;midkine (neurite growth-promoting factor 2),GO:0005576//extracellular region,"GO:0030325//adrenal gland development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0051384//response to glucocorticoid;GO:0007614//short-term memory;GO:0021987//cerebral cortex development;GO:0030421//defecation;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0016477//cell migration;GO:0051781//positive regulation of cell division;GO:0021542//dentate gyrus development;GO:0043524//negative regulation of neuron apoptotic process;GO:0050795//regulation of behavior;GO:0009611//response to wounding;GO:0007165//signal transduction;GO:0001662//behavioral fear response;GO:0021681//cerebellar granular layer development;GO:0007219//Notch signaling pathway",GO:0008201//heparin binding;GO:0008083//growth factor activity,-
4193,53,52,56,34,308,37,17,0,56,0,21,0,"MDM2;MDM2 proto-oncogene, E3 ubiquitin protein ligase",GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0030666//endocytic vesicle membrane;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0071312//cellular response to alkaloid;GO:0016032//viral process;GO:0046827//positive regulation of protein export from nucleus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045184//establishment of protein localization;GO:0018205//peptidyl-lysine modification;GO:0046677//response to antibiotic;GO:0071494//cellular response to UV-C;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042220//response to cocaine;GO:0045931//positive regulation of mitotic cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0045087//innate immune response;GO:0006461//protein complex assembly;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045472//response to ether;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0007089//traversing start control point of mitotic cell cycle;GO:0032026//response to magnesium ion;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0071375//cellular response to peptide hormone stimulus;GO:0010955//negative regulation of protein processing;GO:0043278//response to morphine;GO:0071301//cellular response to vitamin B1;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0009743//response to carbohydrate;GO:0031648//protein destabilization;GO:0007268//synaptic transmission;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042176//regulation of protein catabolic process;GO:0071229//cellular response to acid chemical;GO:0034504//protein localization to nucleus;GO:0071456//cellular response to hypoxia;GO:0010039//response to iron ion;GO:0071391//cellular response to estrogen stimulus;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042493//response to drug;GO:0071236//cellular response to antibiotic;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0071157//negative regulation of cell cycle arrest;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016567//protein ubiquitination;GO:0070301//cellular response to hydrogen peroxide",GO:0042975//peroxisome proliferator activated receptor binding;GO:0019899//enzyme binding;GO:0002039//p53 binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0097110//scaffold protein binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K06643//Chronic myeloid leukemia;Melanoma;Cell cycle;Epstein-Barr virus infection;p53 signaling pathway;Bladder cancer;Glioma;Endocytosis;Pathways in cancer;Ubiquitin mediated proteolysis;Transcriptional misregulation in cancer;Prostate cancer
4194,7,0,1,16,3,68,76,0,27,0,16,0,"MDM4;MDM4, p53 regulator",GO:0005634//nucleus,"GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042177//negative regulation of protein catabolic process;GO:0050821//protein stabilization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071157//negative regulation of cell cycle arrest;GO:0008283//cell proliferation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0045023//G0 to G1 transition;GO:0071456//cellular response to hypoxia;GO:0008284//positive regulation of cell proliferation;GO:0006461//protein complex assembly",GO:0019899//enzyme binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,K10127//p53 signaling pathway
4199,0,18,0,0,1,0,52,0,52,0,0,0,"ME1;malic enzyme 1, NADP(+)-dependent, cytosolic",GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0009725//response to hormone;GO:0006108//malate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044255//cellular lipid metabolic process;GO:0009743//response to carbohydrate;GO:0006741//NADP biosynthetic process;GO:0055114//oxidation-reduction process;GO:0051262//protein tetramerization,GO:0004470//malic enzyme activity;GO:0050661//NADP binding;GO:0030145//manganese ion binding;GO:0051287//NAD binding;GO:0004473//malate dehydrogenase (decarboxylating) (NADP+) activity;GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0043531//ADP binding;GO:0009055//electron carrier activity;GO:0008948//oxaloacetate decarboxylase activity,K00029//Carbon fixation in photosynthetic organisms;Pyruvate metabolism;Microbial metabolism in diverse environments;Metabolic pathways;PPAR signaling pathway
420,0,0,0,0,0,0,0,34,24,0,0,0,ART4;ADP-ribosyltransferase 4 (Dombrock blood group),GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0006525//arginine metabolic process;GO:0006471//protein ADP-ribosylation,GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity,-
4200,70,38,0,19,58,14,0,0,58,0,16,0,"ME2;malic enzyme 2, NAD(+)-dependent, mitochondrial",GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005759//mitochondrial matrix,GO:0006108//malate metabolic process;GO:0055114//oxidation-reduction process,GO:0004471//malate dehydrogenase (decarboxylating) (NAD+) activity;GO:0009055//electron carrier activity;GO:0051287//NAD binding;GO:0008948//oxaloacetate decarboxylase activity;GO:0046872//metal ion binding,K00027//Two-component system;Pyruvate metabolism;Metabolic pathways
4201,0,97,96,119,108,0,0,0,0,0,107,0,MEA1;male-enhanced antigen 1,GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0030154//cell differentiation,GO:0005515//protein binding,-
4204,0,79,2,34,167,57,32,3,25,230,17,20,MECP2;methyl CpG binding protein 2,GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005829//cytosol,"GO:0009405//pathogenesis;GO:0008284//positive regulation of cell proliferation;GO:0019230//proprioception;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0031061//negative regulation of histone methylation;GO:0006351//transcription, DNA-templated;GO:0035067//negative regulation of histone acetylation;GO:0050432//catecholamine secretion;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0046470//phosphatidylcholine metabolic process;GO:0007416//synapse assembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0008344//adult locomotory behavior;GO:0008542//visual learning;GO:0019233//sensory perception of pain;GO:0016573//histone acetylation;GO:0009791//post-embryonic development;GO:0001964//startle response;GO:0016358//dendrite development;GO:0035176//social behavior;GO:0006020//inositol metabolic process;GO:0060291//long-term synaptic potentiation;GO:0007585//respiratory gaseous exchange;GO:0016571//histone methylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021549//cerebellum development;GO:0006349//regulation of gene expression by genetic imprinting;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006541//glutamine metabolic process;GO:0008104//protein localization;GO:0007616//long-term memory;GO:0008211//glucocorticoid metabolic process;GO:0042551//neuron maturation;GO:0001662//behavioral fear response;GO:0051965//positive regulation of synapse assembly;GO:0021591//ventricular system development;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0006342//chromatin silencing;GO:0001666//response to hypoxia;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0035197//siRNA binding;GO:0008134//transcription factor binding;GO:0008327//methyl-CpG binding;GO:0010385//double-stranded methylated DNA binding;GO:0003729//mRNA binding;GO:0003677//DNA binding;GO:0019904//protein domain specific binding;GO:0047485//protein N-terminus binding;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding,-
4205,0,0,0,30,41,0,0,0,16,0,3,0,MEF2A;myocyte enhancer factor 2A,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0000002//mitochondrial genome maintenance;GO:0042692//muscle cell differentiation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061337//cardiac conduction;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048311//mitochondrion distribution;GO:0051149//positive regulation of muscle cell differentiation;GO:0071277//cellular response to calcium ion;GO:0055005//ventricular cardiac myofibril assembly;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000165//MAPK cascade;GO:0007517//muscle organ development;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007507//heart development;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0070375//ERK5 cascade;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0048813//dendrite morphogenesis",GO:0001105//RNA polymerase II transcription coactivator activity;GO:0019901//protein kinase binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0033613//activating transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0035035//histone acetyltransferase binding;GO:0046332//SMAD binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
4208,0,0,0,0,0,14,0,0,61,147,8,0,MEF2C;myocyte enhancer factor 2C,GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0030017//sarcomere;GO:0005737//cytoplasm,"GO:0003138//primary heart field specification;GO:0021542//dentate gyrus development;GO:0003211//cardiac ventricle formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060025//regulation of synaptic activity;GO:0010694//positive regulation of alkaline phosphatase activity;GO:0001958//endochondral ossification;GO:0003139//secondary heart field specification;GO:0048643//positive regulation of skeletal muscle tissue development;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0006915//apoptotic process;GO:0003185//sinoatrial valve morphogenesis;GO:0001782//B cell homeostasis;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0051963//regulation of synapse assembly;GO:0042100//B cell proliferation;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030279//negative regulation of ossification;GO:0046928//regulation of neurotransmitter secretion;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045669//positive regulation of osteoblast differentiation;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0030890//positive regulation of B cell proliferation;GO:0050853//B cell receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0035690//cellular response to drug;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000165//MAPK cascade;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0001649//osteoblast differentiation;GO:0030318//melanocyte differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0030501//positive regulation of bone mineralization;GO:0030220//platelet formation;GO:0001764//neuron migration;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0071300//cellular response to retinoic acid;GO:0030224//monocyte differentiation;GO:0071333//cellular response to glucose stimulus;GO:0007517//muscle organ development;GO:0045087//innate immune response;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0071498//cellular response to fluid shear stress;GO:0010629//negative regulation of gene expression;GO:0001568//blood vessel development;GO:0007507//heart development;GO:0060998//regulation of dendritic spine development;GO:2000111//positive regulation of macrophage apoptotic process;GO:0033197//response to vitamin E;GO:0060021//palate development;GO:0002634//regulation of germinal center formation;GO:0009615//response to virus;GO:0034146//toll-like receptor 5 signaling pathway;GO:0061333//renal tubule morphogenesis;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045652//regulation of megakaryocyte differentiation;GO:0014902//myotube differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0042692//muscle cell differentiation;GO:0030182//neuron differentiation;GO:0006959//humoral immune response;GO:0007521//muscle cell fate determination;GO:2001016//positive regulation of skeletal muscle cell differentiation;GO:0007399//nervous system development;GO:0051149//positive regulation of muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071277//cellular response to calcium ion;GO:0090073//positive regulation of protein homodimerization activity;GO:0045663//positive regulation of myoblast differentiation;GO:0034134//toll-like receptor 2 signaling pathway;GO:0001974//blood vessel remodeling;GO:0043406//positive regulation of MAP kinase activity;GO:0007611//learning or memory;GO:0043523//regulation of neuron apoptotic process;GO:0048167//regulation of synaptic plasticity;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0001947//heart looping;GO:0014033//neural crest cell differentiation;GO:0002062//chondrocyte differentiation;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0060536//cartilage morphogenesis;GO:0060297//regulation of sarcomere organization;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0003151//outflow tract morphogenesis;GO:0071222//cellular response to lipopolysaccharide;GO:0035984//cellular response to trichostatin A;GO:0051145//smooth muscle cell differentiation;GO:0002467//germinal center formation;GO:0007519//skeletal muscle tissue development;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0034162//toll-like receptor 9 signaling pathway;GO:2000987//positive regulation of behavioral fear response;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0048666//neuron development;GO:0002931//response to ischemia;GO:0072160//nephron tubule epithelial cell differentiation;GO:0048703//embryonic viscerocranium morphogenesis;GO:0072102//glomerulus morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010628//positive regulation of gene expression",GO:0003677//DNA binding;GO:0003680//AT DNA binding;GO:0071837//HMG box domain binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0035198//miRNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0033613//activating transcription factor binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K04454//MAPK signaling pathway;Transcriptional misregulation in cancer
4209,0,0,1,0,11,0,0,0,57,0,0,0,MEF2D;myocyte enhancer factor 2D,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0002062//chondrocyte differentiation;GO:0007517//muscle organ development;GO:0007399//nervous system development;GO:0001649//osteoblast differentiation;GO:0001958//endochondral ossification;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007512//adult heart development,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0033613//activating transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
421,0,0,0,0,0,25,28,0,16,139,24,0,ARVCF;armadillo repeat gene deleted in velocardiofacial syndrome,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0016337//single organismal cell-cell adhesion;GO:0007155//cell adhesion,GO:0005515//protein binding,K05690//Leukocyte transendothelial migration;Adherens junction
4210,16,0,53,0,0,0,53,0,30,103,0,0,MEFV;Mediterranean fever,GO:0005634//nucleus;GO:0005874//microtubule;GO:0030027//lamellipodium;GO:0005875//microtubule associated complex;GO:0005829//cytosol;GO:0001726//ruffle,"GO:0006954//inflammatory response;GO:0071641//negative regulation of macrophage inflammatory protein 1 alpha production;GO:0045087//innate immune response;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0032691//negative regulation of interleukin-1 beta production;GO:0050728//negative regulation of inflammatory response;GO:0032695//negative regulation of interleukin-12 production;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway",GO:0003779//actin binding;GO:0008270//zinc ion binding,K12803//NOD-like receptor signaling pathway
4211,0,0,0,0,3,0,0,30,8,119,11,1,MEIS1;Meis homeobox 1,GO:0005634//nucleus;GO:0005667//transcription factor complex,GO:0002089//lens morphogenesis in camera-type eye;GO:0001525//angiogenesis;GO:0060216//definitive hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation;GO:0035855//megakaryocyte development;GO:0006366//transcription from RNA polymerase II promoter;GO:0045665//negative regulation of neuron differentiation,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K15613//Transcriptional misregulation in cancer
4212,0,0,1,16,21,26,29,0,46,1,5,320,MEIS2;Meis homeobox 2,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation;GO:0031016//pancreas development;GO:0070848//response to growth factor;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0001654//eye development;GO:0006366//transcription from RNA polymerase II promoter,GO:0003712//transcription cofactor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003714//transcription corepressor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer
4213,0,0,0,0,0,0,0,0,51,0,0,0,MEIS3P1;Meis homeobox 3 pseudogene 1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,K15613//Transcriptional misregulation in cancer
4214,1,0,0,1,62,13,8,0,71,185,0,0,"MAP3K1;mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase",GO:0005829//cytosol,GO:0030838//positive regulation of actin filament polymerization;GO:0008637//apoptotic mitochondrial changes;GO:0030334//regulation of cell migration;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007257//activation of JUN kinase activity;GO:0071260//cellular response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0061029//eyelid development in camera-type eye;GO:0045087//innate immune response;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0042060//wound healing;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000186//activation of MAPKK activity;GO:0003382//epithelial cell morphogenesis;GO:0002224//toll-like receptor signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0008545//JUN kinase kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding,K04416//Ubiquitin mediated proteolysis;RIG-I-like receptor signaling pathway;GnRH signaling pathway;MAPK signaling pathway;Neurotrophin signaling pathway;HTLV-I infection
4215,1,0,0,0,14,0,29,86,76,0,0,0,MAP3K3;mitogen-activated protein kinase kinase kinase 3,GO:0005829//cytosol,GO:0000165//MAPK cascade;GO:0000186//activation of MAPKK activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046777//protein autophosphorylation;GO:0035556//intracellular signal transduction,GO:0005524//ATP binding;GO:0004709//MAP kinase kinase kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity,K04421//HTLV-I infection;Neurotrophin signaling pathway;MAPK signaling pathway;GnRH signaling pathway
4216,0,0,0,0,0,9,0,0,0,0,0,0,MAP3K4;mitogen-activated protein kinase kinase kinase 4,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0001890//placenta development;GO:0060718//chorionic trophoblast cell differentiation;GO:0010225//response to UV-C;GO:0000186//activation of MAPKK activity;GO:0010468//regulation of gene expression;GO:0000165//MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:1900745//positive regulation of p38MAPK cascade;GO:0019100//male germ-line sex determination,GO:0005524//ATP binding;GO:0004709//MAP kinase kinase kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K04428//GnRH signaling pathway;MAPK signaling pathway
4217,98,1,0,34,113,45,46,0,41,0,0,0,MAP3K5;mitogen-activated protein kinase kinase kinase 5,GO:1902911//protein kinase complex;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0016032//viral process;GO:1901216//positive regulation of neuron death;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0007257//activation of JUN kinase activity;GO:1902170//cellular response to reactive nitrogen species;GO:0097300//programmed necrotic cell death;GO:0007254//JNK cascade;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0070301//cellular response to hydrogen peroxide;GO:0002931//response to ischemia;GO:0000186//activation of MAPKK activity;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0000165//MAPK cascade,GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0000287//magnesium ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K04426//Neurotrophin signaling pathway;Amyotrophic lateral sclerosis (ALS);MAPK signaling pathway;Protein processing in endoplasmic reticulum
4218,0,0,0,9,71,0,0,44,20,0,7,0,"RAB8A;RAB8A, member RAS oncogene family",GO:0043025//neuronal cell body;GO:0005813//centrosome;GO:0031513//nonmotile primary cilium;GO:0045335//phagocytic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0055038//recycling endosome membrane;GO:0014069//postsynaptic density;GO:0030140//trans-Golgi network transport vesicle;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0036064//ciliary basal body;GO:0072372//primary cilium;GO:0005929//cilium,GO:0007409//axonogenesis;GO:0048210//Golgi vesicle fusion to target membrane;GO:0007264//small GTPase mediated signal transduction;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0015031//protein transport;GO:0051223//regulation of protein transport;GO:0042384//cilium assembly;GO:0061024//membrane organization;GO:0072659//protein localization to plasma membrane;GO:0032869//cellular response to insulin stimulus;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0006184//GTP catabolic process;GO:0006904//vesicle docking involved in exocytosis,GO:0017137//Rab GTPase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding,K07901//Pancreatic secretion
4221,88,0,0,1,1,0,0,1,33,0,1,0,MEN1;multiple endocrine neoplasia I,GO:0032154//cleavage furrow;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0035097//histone methyltransferase complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0000785//chromatin;GO:0016363//nuclear matrix;GO:0005634//nucleus,"GO:0046329//negative regulation of JNK cascade;GO:0043065//positive regulation of apoptotic process;GO:0046621//negative regulation of organ growth;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006281//DNA repair;GO:0034968//histone lysine methylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031062//positive regulation of histone methylation;GO:0010332//response to gamma radiation;GO:0000165//MAPK cascade;GO:0045669//positive regulation of osteoblast differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0002076//osteoblast development;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0048704//embryonic skeletal system morphogenesis;GO:0002051//osteoblast fate commitment;GO:0006338//chromatin remodeling;GO:0030097//hemopoiesis;GO:0060135//maternal process involved in female pregnancy;GO:0001776//leukocyte homeostasis;GO:0007050//cell cycle arrest;GO:0045786//negative regulation of cell cycle;GO:0051781//positive regulation of cell division;GO:0060021//palate development;GO:0051974//negative regulation of telomerase activity;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0007420//brain development;GO:0032092//positive regulation of protein binding;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0001933//negative regulation of protein phosphorylation;GO:0009411//response to UV;GO:0032925//regulation of activin receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway","GO:0030674//protein binding, bridging;GO:0043565//sequence-specific DNA binding;GO:0000400//four-way junction DNA binding;GO:0047485//protein N-terminus binding;GO:0070412//R-SMAD binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0000403//Y-form DNA binding",K14970//Transcriptional misregulation in cancer
4222,0,9,0,0,0,0,0,0,9,0,0,0,MEOX1;mesenchyme homeobox 1,GO:0005634//nucleus,GO:0001757//somite specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development,GO:0071837//HMG box domain binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
4223,0,0,0,0,0,0,28,0,0,0,0,0,MEOX2;mesenchyme homeobox 2,GO:0016607//nuclear speck;GO:0005737//cytoplasm,GO:0007519//skeletal muscle tissue development;GO:0001757//somite specification;GO:0060021//palate development;GO:0007275//multicellular organismal development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060173//limb development;GO:0001525//angiogenesis;GO:0070997//neuron death;GO:0008015//blood circulation,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
4224,0,0,0,0,0,0,35,0,34,0,0,0,"MEP1A;meprin A, alpha (PABA peptide hydrolase)",GO:0005887//integral component of plasma membrane;GO:0017090//meprin A complex;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0007586//digestion;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004222//metalloendopeptidase activity,K01395//Protein digestion and absorption
4225,64,0,0,0,0,0,0,186,57,0,0,0,"MEP1B;meprin A, beta",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:0007586//digestion;GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K08606//Protein digestion and absorption
4232,0,0,0,0,0,0,1,0,19,0,0,0,MEST;mesoderm specific transcript,GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0007498//mesoderm development;GO:0008152//metabolic process;GO:0032526//response to retinoic acid;GO:0010883//regulation of lipid storage,GO:0016787//hydrolase activity,-
4233,0,0,0,0,0,18,22,0,16,0,7,0,"MET;MET proto-oncogene, receptor tyrosine kinase",GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane,GO:1901299//negative regulation of hydrogen peroxide-mediated programmed cell death;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0001889//liver development;GO:0042593//glucose homeostasis;GO:0050918//positive chemotaxis;GO:0071526//semaphorin-plexin signaling pathway;GO:0007420//brain development;GO:0001890//placenta development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0008283//cell proliferation;GO:0000187//activation of MAPK activity;GO:0048754//branching morphogenesis of an epithelial tube;GO:0014902//myotube differentiation;GO:0046777//protein autophosphorylation;GO:0060665//regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling;GO:0001886//endothelial cell morphogenesis;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0007165//signal transduction;GO:0014812//muscle cell migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010828//positive regulation of glucose transport;GO:0051450//myoblast proliferation;GO:0007519//skeletal muscle tissue development;GO:0007166//cell surface receptor signaling pathway;GO:0030534//adult behavior,GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0004713//protein tyrosine kinase activity;GO:0005008//hepatocyte growth factor-activated receptor activity;GO:0005515//protein binding,K05099//Transcriptional misregulation in cancer;Pathways in cancer;Malaria;Axon guidance;Bacterial invasion of epithelial cells;Endocytosis;Adherens junction;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection;Focal adhesion;Melanoma;Cytokine-cytokine receptor interaction
4234,0,0,0,0,15,1,20,0,9,0,3,0,METTL1;methyltransferase like 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006400//tRNA modification;GO:0030488//tRNA methylation;GO:0036265//RNA (guanine-N7)-methylation,GO:0000049//tRNA binding;GO:0008176//tRNA (guanine-N7-)-methyltransferase activity;GO:0005515//protein binding,-
4236,0,30,1,11,90,0,47,0,61,0,7,0,MFAP1;microfibrillar-associated protein 1,GO:0005576//extracellular region;GO:0001527//microfibril,GO:0030198//extracellular matrix organization,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
4237,0,0,0,8,0,0,0,0,13,0,0,0,MFAP2;microfibrillar-associated protein 2,GO:0001527//microfibril;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0030220//platelet formation,GO:0001968//fibronectin binding;GO:0070051//fibrinogen binding,K10989//Primary immunodeficiency;Intestinal immune network for IgA production
4238,0,1,0,0,7,8,7,0,41,0,0,0,MFAP3;microfibrillar-associated protein 3,GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0030198//extracellular matrix organization,-,-
4239,0,0,0,0,0,0,6,0,0,0,12,0,MFAP4;microfibrillar-associated protein 4,GO:0071953//elastic fiber;GO:0001527//microfibril;GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0048251//elastic fiber assembly;GO:0007155//cell adhesion;GO:0010712//regulation of collagen metabolic process;GO:0009650//UV protection;GO:0071493//cellular response to UV-B;GO:0043206//extracellular fibril organization;GO:0030198//extracellular matrix organization,GO:0005515//protein binding,-
4240,95,0,0,0,0,0,19,0,19,0,0,0,MFGE8;milk fat globule-EGF factor 8 protein,GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0016020//membrane;GO:0031982//vesicle;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0019897//extrinsic component of plasma membrane,"GO:0006910//phagocytosis, recognition;GO:0006911//phagocytosis, engulfment;GO:0016032//viral process;GO:2000427//positive regulation of apoptotic cell clearance;GO:0007338//single fertilization;GO:0007155//cell adhesion;GO:0001525//angiogenesis",GO:0005178//integrin binding;GO:0008429//phosphatidylethanolamine binding;GO:0001786//phosphatidylserine binding,K03902//Complement and coagulation cascades
4241,0,45,104,14,0,19,14,1,63,33,30,388,MFI2;antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0046658//anchored component of plasma membrane,GO:0042127//regulation of cell proliferation;GO:0097286//iron ion import;GO:0001558//regulation of cell growth;GO:0010756//positive regulation of plasminogen activation;GO:0006879//cellular iron ion homeostasis;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0090091//positive regulation of extracellular matrix disassembly,GO:0008199//ferric iron binding;GO:0005515//protein binding;GO:0005506//iron ion binding,-
4242,0,32,0,0,0,0,45,0,0,0,0,0,MFNG;MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,GO:0005615//extracellular space;GO:0030173//integral component of Golgi membrane,GO:0032092//positive regulation of protein binding;GO:0008152//metabolic process;GO:0045747//positive regulation of Notch signaling pathway;GO:0007389//pattern specification process,GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding,K05948//Other types of O-glycan biosynthesis;Notch signaling pathway
4245,102,0,0,0,0,12,91,0,40,0,0,0,"MGAT1;mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase",GO:0031982//vesicle;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0001701//in utero embryonic development;GO:0006486//protein glycosylation;GO:0006049//UDP-N-acetylglucosamine catabolic process;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,"GO:0003827//alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity;GO:0046872//metal ion binding",K00726//Metabolic pathways;N-Glycan biosynthesis
4246,0,0,0,0,0,0,0,47,5,0,0,0,"SCGB2A1;secretoglobin, family 2A, member 1",GO:0005615//extracellular space,GO:0030521//androgen receptor signaling pathway,GO:0046982//protein heterodimerization activity,-
4247,0,0,0,0,0,20,0,0,0,0,0,0,"MGAT2;mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005795//Golgi stack,GO:0009312//oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0009311//oligosaccharide metabolic process;GO:0006487//protein N-linked glycosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,"GO:0008455//alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity;GO:0030246//carbohydrate binding",K00736//Metabolic pathways;N-Glycan biosynthesis
4248,0,0,0,0,8,0,0,34,6,0,0,0,"MGAT3;mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,"GO:0003830//beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity",K00737//Metabolic pathways;N-Glycan biosynthesis
4249,0,0,0,0,0,8,25,0,28,0,16,0,"MGAT5;mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase",GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification,"GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity",K00744//N-Glycan biosynthesis;Metabolic pathways
425054,0,0,0,0,0,17,0,0,0,0,4,0,"VCX3B;variable charge, X-linked 3B",GO:0005730//nucleolus;GO:0005634//nucleus,-,-,K10583//Ubiquitin mediated proteolysis
4253,95,161,0,25,79,12,19,0,44,0,51,0,"CTAGE5;CTAGE family, member 5",GO:0016020//membrane,GO:0043085//positive regulation of catalytic activity,GO:0008047//enzyme activator activity,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K12472//Endocytosis
4254,82,0,0,8,0,23,39,0,69,0,3,1,KITLG;KIT ligand,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0048015//phosphatidylinositol-mediated signaling;GO:0008283//cell proliferation;GO:0043406//positive regulation of MAP kinase activity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0033026//negative regulation of mast cell apoptotic process;GO:0046579//positive regulation of Ras protein signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008584//male gonad development;GO:0035234//ectopic germ cell programmed cell death;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007155//cell adhesion;GO:0001755//neural crest cell migration;GO:0070668//positive regulation of mast cell proliferation;GO:0045740//positive regulation of DNA replication;GO:0035162//embryonic hemopoiesis;GO:0002763//positive regulation of myeloid leukocyte differentiation;GO:0045636//positive regulation of melanocyte differentiation;GO:0007165//signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005173//stem cell factor receptor binding;GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0005125//cytokine activity,K05461//Pathways in cancer;Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Melanogenesis
4255,0,24,0,0,14,8,31,0,0,0,8,0,MGMT;O-6-methylguanine-DNA methyltransferase,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016020//membrane,GO:0034599//cellular response to oxidative stress;GO:0071479//cellular response to ionizing radiation;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051593//response to folic acid;GO:0042493//response to drug;GO:0006306//DNA methylation;GO:0009636//response to toxic substance;GO:0006281//DNA repair;GO:0060644//mammary gland epithelial cell differentiation;GO:0006266//DNA ligation;GO:0045739//positive regulation of DNA repair;GO:0006307//DNA dealkylation involved in DNA repair;GO:0071407//cellular response to organic cyclic compound;GO:0045471//response to ethanol;GO:0060548//negative regulation of cell death,GO:0008168//methyltransferase activity;GO:0009008//DNA-methyltransferase activity;GO:0003677//DNA binding;GO:0005509//calcium ion binding;GO:0003908//methylated-DNA-[protein]-cysteine S-methyltransferase activity,K00567//Base excision repair
4257,0,1,0,11,45,16,0,0,27,0,0,0,MGST1;microsomal glutathione S-transferase 1,GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005778//peroxisomal membrane;GO:0005741//mitochondrial outer membrane;GO:0045177//apical part of cell,GO:0070207//protein homotrimerization;GO:0032496//response to lipopolysaccharide;GO:0006749//glutathione metabolic process;GO:0055114//oxidation-reduction process;GO:0071449//cellular response to lipid hydroperoxide;GO:0042493//response to drug;GO:1901687//glutathione derivative biosynthetic process;GO:0010243//response to organonitrogen compound;GO:0033327//Leydig cell differentiation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0043295//glutathione binding;GO:0004364//glutathione transferase activity;GO:0004602//glutathione peroxidase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
4258,1,0,0,0,13,0,0,0,8,0,3,0,MGST2;microsomal glutathione S-transferase 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0006750//glutathione biosynthetic process;GO:1901687//glutathione derivative biosynthetic process;GO:0043085//positive regulation of catalytic activity;GO:0055114//oxidation-reduction process,GO:0004364//glutathione transferase activity;GO:0004464//leukotriene-C4 synthase activity;GO:0008047//enzyme activator activity;GO:0004602//glutathione peroxidase activity,K00799//Prostate cancer;Glutathione metabolism;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
4259,0,19,1,11,54,0,0,0,0,0,0,0,MGST3;microsomal glutathione S-transferase 3,GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006629//lipid metabolic process;GO:0055114//oxidation-reduction process;GO:1901687//glutathione derivative biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process,GO:0004602//glutathione peroxidase activity;GO:0004601//peroxidase activity;GO:0004364//glutathione transferase activity,K00799//Glutathione metabolism;Prostate cancer;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
4261,77,0,0,0,0,34,0,0,106,0,0,0,"CIITA;class II, major histocompatibility complex, transactivator",GO:0016605//PML body;GO:0009986//cell surface;GO:0005654//nucleoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0006955//immune response;GO:0032966//negative regulation of collagen biosynthetic process;GO:0046677//response to antibiotic;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071360//cellular response to exogenous dsRNA;GO:0034341//response to interferon-gamma;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071257//cellular response to electrical stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0016310//phosphorylation;GO:0007568//aging","GO:0005515//protein binding;GO:0016746//transferase activity, transferring acyl groups;GO:0008022//protein C-terminus binding;GO:0044212//transcription regulatory region DNA binding;GO:0033613//activating transcription factor binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity;GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0016301//kinase activity;GO:0005525//GTP binding",K08060//Toxoplasmosis;Primary immunodeficiency;Antigen processing and presentation;Tuberculosis;Influenza A
4267,0,10,0,22,3,0,0,27,2,0,0,0,CD99;CD99 molecule,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0007155//cell adhesion,-,K06520//Leukocyte transendothelial migration;Cell adhesion molecules (CAMs)
427,1,104,0,44,12,10,34,0,10,0,0,0,ASAH1;N-acylsphingosine amidohydrolase (acid ceramidase) 1,GO:0043202//lysosomal lumen;GO:0070062//extracellular vesicular exosome,GO:0006687//glycosphingolipid metabolic process;GO:0006672//ceramide metabolic process;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0008219//cell death;GO:0010033//response to organic substance;GO:0030324//lung development,GO:0003824//catalytic activity;GO:0017040//ceramidase activity,K12348//Metabolic pathways;Sphingolipid metabolism;Lysosome
4277,3,20,0,0,0,0,3,0,10,0,0,0,MICB;MHC class I polypeptide-related sequence B,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0032526//response to retinoic acid;GO:0016032//viral process;GO:0050689//negative regulation of defense response to virus by host;GO:0002429//immune response-activating cell surface receptor signaling pathway;GO:0009408//response to heat;GO:0006955//immune response;GO:0019835//cytolysis;GO:0019882//antigen processing and presentation;GO:0006979//response to oxidative stress;GO:0046629//gamma-delta T cell activation,GO:0046703//natural killer cell lectin-like receptor binding,K07985//Natural killer cell mediated cytotoxicity
4281,0,28,0,25,45,14,24,1,85,0,3,0,MID1;midline 1,GO:0005881//cytoplasmic microtubule;GO:0005875//microtubule associated complex;GO:0005819//spindle;GO:0005874//microtubule,GO:0007389//pattern specification process;GO:0007026//negative regulation of microtubule depolymerization;GO:0035372//protein localization to microtubule;GO:0000226//microtubule cytoskeleton organization;GO:0008152//metabolic process;GO:0032874//positive regulation of stress-activated MAPK cascade,GO:0016874//ligase activity;GO:0008017//microtubule binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0051219//phosphoprotein binding;GO:0008270//zinc ion binding,K08285//Ubiquitin mediated proteolysis
4282,0,0,0,1,3,0,0,40,16,0,0,0,MIF;macrophage migration inhibitory factor (glycosylation-inhibiting factor),GO:0009986//cell surface;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031982//vesicle;GO:0005737//cytoplasm,"GO:0042327//positive regulation of phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0030890//positive regulation of B cell proliferation;GO:0032269//negative regulation of cellular protein metabolic process;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:0071157//negative regulation of cell cycle arrest;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0006954//inflammatory response;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0010739//positive regulation of protein kinase A signaling;GO:0001516//prostaglandin biosynthetic process;GO:0070207//protein homotrimerization;GO:0061081//positive regulation of myeloid leukocyte cytokine production involved in immune response;GO:0007569//cell aging;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090344//negative regulation of cell aging;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0050918//positive chemotaxis;GO:0010629//negative regulation of gene expression;GO:0061078//positive regulation of prostaglandin secretion involved in immune response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008283//cell proliferation;GO:0090238//positive regulation of arachidonic acid secretion;GO:0050715//positive regulation of cytokine secretion;GO:0048146//positive regulation of fibroblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0019752//carboxylic acid metabolic process;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0007166//cell surface receptor signaling pathway;GO:0043030//regulation of macrophage activation;GO:0002906//negative regulation of mature B cell apoptotic process",GO:0004167//dopachrome isomerase activity;GO:0050178//phenylpyruvate tautomerase activity;GO:0005126//cytokine receptor binding;GO:0005102//receptor binding;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042056//chemoattractant activity,K07253//Phenylalanine metabolism;Tyrosine metabolism
4283,0,0,0,0,0,32,0,19,11,0,0,0,CXCL9;chemokine (C-X-C motif) ligand 9,GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006968//cellular defense response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0051607//defense response to virus;GO:0006952//defense response;GO:0042127//regulation of cell proliferation;GO:0060326//cell chemotaxis;GO:0007165//signal transduction;GO:0030816//positive regulation of cAMP metabolic process,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008009//chemokine activity;GO:0048248//CXCR3 chemokine receptor binding,K05416//Toll-like receptor signaling pathway;Cytokine-cytokine receptor interaction;Chemokine signaling pathway
4284,0,0,0,0,0,0,0,0,6,245,0,0,MIP;major intrinsic protein of lens fiber,GO:0005887//integral component of plasma membrane;GO:0005921//gap junction;GO:0046691//intracellular canaliculus;GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane,GO:0007601//visual perception;GO:0006833//water transport;GO:0002088//lens development in camera-type eye;GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0015722//canalicular bile acid transport,GO:0005516//calmodulin binding;GO:0005215//transporter activity;GO:0015250//water channel activity;GO:0005212//structural constituent of eye lens,-
4285,0,208,100,90,69,0,0,206,53,0,545,425,MIPEP;mitochondrial intermediate peptidase,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
4286,63,22,0,0,1,16,20,49,60,0,0,1,MITF;microphthalmia-associated transcription factor,GO:0043234//protein complex;GO:0005634//nucleus,"GO:0030318//melanocyte differentiation;GO:0043010//camera-type eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0006461//protein complex assembly;GO:0042127//regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045670//regulation of osteoclast differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046849//bone remodeling;GO:0006366//transcription from RNA polymerase II promoter;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0030316//osteoclast differentiation",GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,K09455//Osteoclast differentiation;Pathways in cancer;Melanoma;Melanogenesis
4287,0,17,0,17,39,48,21,0,37,0,0,0,ATXN3;ataxin 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0010810//regulation of cell-substrate adhesion;GO:0071108//protein K48-linked deubiquitination;GO:0071218//cellular response to misfolded protein;GO:0006289//nucleotide-excision repair;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization;GO:0035520//monoubiquitinated protein deubiquitination;GO:0008219//cell death;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0045104//intermediate filament cytoskeleton organization;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0030036//actin cytoskeleton organization;GO:0006351//transcription, DNA-templated;GO:0070536//protein K63-linked deubiquitination",GO:0008242//omega peptidase activity;GO:1990380//Lys48-specific deubiquitinase activity;GO:0004221//ubiquitin thiolesterase activity;GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0051117//ATPase binding;GO:0061578//Lys63-specific deubiquitinase activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding,K11863//Protein processing in endoplasmic reticulum;K11447//Transcriptional misregulation in cancer
4288,67,0,0,0,0,19,1,7,36,140,9,0,MKI67;marker of proliferation Ki-67,"GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0016020//membrane;GO:0000793//condensed chromosome;GO:0005730//nucleolus",GO:0006259//DNA metabolic process;GO:0030212//hyaluronan metabolic process;GO:0034605//cellular response to heat;GO:0014070//response to organic cyclic compound;GO:0007126//meiotic nuclear division;GO:0008283//cell proliferation;GO:0031100//organ regeneration,GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
4289,110,0,5,120,403,0,74,0,59,0,0,0,"MKLN1;muskelin 1, intracellular mediator containing kelch motifs",GO:0005737//cytoplasm,GO:0007165//signal transduction,-,K11447//Transcriptional misregulation in cancer
429,0,0,0,0,0,0,0,0,48,0,0,0,ASCL1;achaete-scute family bHLH transcription factor 1,GO:0005634//nucleus;GO:0043025//neuronal cell body,"GO:0043066//negative regulation of apoptotic process;GO:0006351//transcription, DNA-templated;GO:0021750//vestibular nucleus development;GO:0043525//positive regulation of neuron apoptotic process;GO:0010226//response to lithium ion;GO:0070849//response to epidermal growth factor;GO:0048469//cell maturation;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0048665//neuron fate specification;GO:0050883//musculoskeletal movement, spinal reflex action;GO:0021987//cerebral cortex development;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0001764//neuron migration;GO:0045666//positive regulation of neuron differentiation;GO:0050769//positive regulation of neurogenesis;GO:0060166//olfactory pit development;GO:0045787//positive regulation of cell cycle;GO:0051593//response to folic acid;GO:0022008//neurogenesis;GO:0021892//cerebral cortex GABAergic interneuron differentiation;GO:0003358//noradrenergic neuron development;GO:0061104//adrenal chromaffin cell differentiation;GO:0045665//negative regulation of neuron differentiation;GO:0061549//sympathetic ganglion development;GO:0003359//noradrenergic neuron fate commitment;GO:0048485//sympathetic nervous system development;GO:0045747//positive regulation of Notch signaling pathway;GO:0021527//spinal cord association neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060487//lung epithelial cell differentiation;GO:0010468//regulation of gene expression;GO:0007346//regulation of mitotic cell cycle;GO:0007219//Notch signaling pathway;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0060579//ventral spinal cord interneuron fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021954//central nervous system neuron development;GO:0030856//regulation of epithelial cell differentiation;GO:0007405//neuroblast proliferation;GO:0032526//response to retinoic acid;GO:0014003//oligodendrocyte development",GO:0043425//bHLH transcription factor binding;GO:0003682//chromatin binding;GO:0000989//transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0070888//E-box binding,-
4291,0,1,6,14,13,28,1,74,33,124,0,0,MLF1;myeloid leukemia factor 1,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0002318//myeloid progenitor cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding,K15622//Transcriptional misregulation in cancer
4292,0,32,23,43,30,0,38,0,30,0,4,0,MLH1;mutL homolog 1,GO:0005634//nucleus;GO:0000795//synaptonemal complex;GO:0001673//male germ cell nucleus;GO:0032389//MutLalpha complex;GO:0005730//nucleolus;GO:0005712//chiasma;GO:0016020//membrane,GO:0051257//spindle midzone assembly involved in meiosis;GO:0000712//resolution of meiotic recombination intermediates;GO:0007129//synapsis;GO:0048477//oogenesis;GO:0007060//male meiosis chromosome segregation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0007283//spermatogenesis;GO:0045950//negative regulation of mitotic recombination;GO:0006298//mismatch repair;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0043060//meiotic metaphase I plate congression;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006200//ATP catabolic process;GO:0045190//isotype switching,GO:0016887//ATPase activity;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0032407//MutSalpha complex binding;GO:0005524//ATP binding;GO:0032137//guanine/thymine mispair binding,K08734//Endometrial cancer;Pathways in cancer;Colorectal cancer;Fanconi anemia pathway;Mismatch repair
4293,59,0,0,9,15,12,64,86,32,0,0,0,MAP3K9;mitogen-activated protein kinase kinase kinase 9,-,"GO:0006355//regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0007257//activation of JUN kinase activity;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0007256//activation of JNKK activity;GO:0043065//positive regulation of apoptotic process;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation",GO:0005524//ATP binding;GO:0004706//JUN kinase kinase kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0042803//protein homodimerization activity;GO:0004708//MAP kinase kinase activity;GO:0005515//protein binding,-
4294,0,0,0,0,8,0,20,0,14,0,18,0,MAP3K10;mitogen-activated protein kinase kinase kinase 10,GO:0005737//cytoplasm,"GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0007254//JNK cascade;GO:0007224//smoothened signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0018107//peptidyl-threonine phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0007256//activation of JNKK activity;GO:0046330//positive regulation of JNK cascade;GO:0007257//activation of JUN kinase activity;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043507//positive regulation of JUN kinase activity",GO:0043425//bHLH transcription factor binding;GO:0004706//JUN kinase kinase kinase activity;GO:0005524//ATP binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity,-
4295,0,0,0,0,0,0,25,0,0,0,0,0,MLN;motilin,GO:0005576//extracellular region,GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005179//hormone activity;GO:0005102//receptor binding,-
4296,19,1,0,0,16,22,0,2,0,1,0,0,MAP3K11;mitogen-activated protein kinase kinase kinase 11,GO:0016020//membrane;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0000187//activation of MAPK activity;GO:0043507//positive regulation of JUN kinase activity;GO:0008283//cell proliferation;GO:0043525//positive regulation of neuron apoptotic process;GO:0007257//activation of JUN kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007017//microtubule-based process;GO:0007256//activation of JNKK activity;GO:0008219//cell death;GO:0007254//JNK cascade;GO:0046777//protein autophosphorylation,GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0048365//Rac GTPase binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0004713//protein tyrosine kinase activity;GO:0004706//JUN kinase kinase kinase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K04419//MAPK signaling pathway
4297,56,147,0,45,130,81,76,143,96,0,6,0,KMT2A;lysine (K)-specific methyltransferase 2A,GO:0005730//nucleolus;GO:0035097//histone methyltransferase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0071339//MLL1 complex,"GO:0006366//transcription from RNA polymerase II promoter;GO:0035162//embryonic hemopoiesis;GO:0032411//positive regulation of transporter activity;GO:0080182//histone H3-K4 trimethylation;GO:0051568//histone H3-K4 methylation;GO:0006915//apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0051569//regulation of histone H3-K4 methylation;GO:0006461//protein complex assembly;GO:2001040//positive regulation of cellular response to drug;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0043984//histone H4-K16 acetylation;GO:0006306//DNA methylation",GO:0045322//unmethylated CpG binding;GO:0003680//AT DNA binding;GO:0042802//identical protein binding;GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding;GO:0044212//transcription regulatory region DNA binding,K09186//Lysine degradation;Transcriptional misregulation in cancer
4298,0,0,0,5,16,12,16,0,6,0,21,315,"MLLT1;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0008023//transcription elongation factor complex;GO:0005730//nucleolus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006469//negative regulation of protein kinase activity;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding,K15187//Transcriptional misregulation in cancer
4299,104,21,0,86,347,11,71,122,95,0,3,0,"AFF1;AF4/FMR2 family, member 1",GO:0008023//transcription elongation factor complex,"GO:0045893//positive regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K15184//Transcriptional misregulation in cancer
43,0,0,0,0,0,0,0,50,1,11,1,0,ACHE;acetylcholinesterase (Yt blood group),GO:0048471//perinuclear region of cytoplasm;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0005605//basal lamina;GO:0045211//postsynaptic membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0030424//axon;GO:0005615//extracellular space;GO:0031225//anchored component of membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0005576//extracellular region;GO:0031594//neuromuscular junction;GO:0016020//membrane;GO:0009986//cell surface,"GO:0051262//protein tetramerization;GO:0042982//amyloid precursor protein metabolic process;GO:0008283//cell proliferation;GO:0001507//acetylcholine catabolic process in synaptic cleft;GO:0006656//phosphatidylcholine biosynthetic process;GO:0050770//regulation of axonogenesis;GO:0046474//glycerophospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007271//synaptic transmission, cholinergic;GO:0042136//neurotransmitter biosynthetic process;GO:0019695//choline metabolic process;GO:0048814//regulation of dendrite morphogenesis;GO:0045212//neurotransmitter receptor biosynthetic process;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0002076//osteoblast development;GO:0007155//cell adhesion;GO:0006260//DNA replication;GO:0001919//regulation of receptor recycling;GO:0007517//muscle organ development;GO:0050714//positive regulation of protein secretion;GO:0006644//phospholipid metabolic process;GO:0060041//retina development in camera-type eye;GO:0007416//synapse assembly;GO:0031623//receptor internalization;GO:0009611//response to wounding;GO:0032223//negative regulation of synaptic transmission, cholinergic",GO:0003990//acetylcholinesterase activity;GO:0043236//laminin binding;GO:0004104//cholinesterase activity;GO:0043621//protein self-association;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042166//acetylcholine binding;GO:0016787//hydrolase activity;GO:0017171//serine hydrolase activity;GO:0005518//collagen binding;GO:0001540//beta-amyloid binding,K01049//Cholinergic synapse;Glycerophospholipid metabolism
430,0,0,0,0,0,0,0,3,5,0,0,0,ASCL2;achaete-scute family bHLH transcription factor 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0001666//response to hypoxia;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060712//spongiotrophoblast layer development;GO:0060708//spongiotrophoblast differentiation;GO:0001890//placenta development;GO:0010626//negative regulation of Schwann cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell maintenance",GO:0046983//protein dimerization activity;GO:0070888//E-box binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
4300,54,0,0,19,21,8,16,0,37,0,0,0,"MLLT3;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3",GO:0005634//nucleus;GO:0008023//transcription elongation factor complex;GO:0070062//extracellular vesicular exosome,"GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0006351//transcription, DNA-templated;GO:0009952//anterior/posterior pattern specification;GO:0007379//segment specification;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,K15187//Transcriptional misregulation in cancer
4301,120,65,4,208,381,9,44,21,59,4,21,0,"MLLT4;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4",GO:0045177//apical part of cell;GO:0005913//cell-cell adherens junction;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0007165//signal transduction;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0007267//cell-cell signaling,GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0008022//protein C-terminus binding,K05702//Adherens junction;Leukocyte transendothelial migration;Tight junction
4302,0,20,52,2,44,0,0,25,32,0,7,0,"MLLT6;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0005515//protein binding,-
4303,5,21,0,0,0,9,23,0,14,0,0,0,FOXO4;forkhead box O4,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0016525//negative regulation of angiogenesis;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007050//cell cycle arrest;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0070317//negative regulation of G0 to G1 transition;GO:0006366//transcription from RNA polymerase II promoter;GO:0048863//stem cell differentiation;GO:0007517//muscle organ development;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0019899//enzyme binding,-
4306,0,0,0,0,22,14,6,0,12,0,38,0,"NR3C2;nuclear receptor subfamily 3, group C, member 2",GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex,"GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0005496//steroid binding,K08555//Aldosterone-regulated sodium reabsorption
4308,45,0,0,0,0,40,20,37,45,0,15,0,"TRPM1;transient receptor potential cation channel, subfamily M, member 1",GO:0005886//plasma membrane;GO:0035841//new growing cell tip;GO:0005887//integral component of plasma membrane,GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0071482//cellular response to light stimulus;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0060402//calcium ion transport into cytosol;GO:0046548//retinal rod cell development;GO:0007601//visual perception,GO:0005262//calcium channel activity,-
4311,40,114,0,180,240,12,0,0,77,0,0,0,MME;membrane metallo-endopeptidase,GO:0005903//brush border;GO:0005887//integral component of plasma membrane;GO:0044306//neuron projection terminus;GO:0030424//axon;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045202//synapse,GO:0046449//creatinine metabolic process;GO:0044267//cellular protein metabolic process;GO:0002003//angiotensin maturation;GO:0006508//proteolysis;GO:0050435//beta-amyloid metabolic process;GO:0071493//cellular response to UV-B;GO:0006518//peptide metabolic process;GO:0090399//replicative senescence;GO:0001822//kidney development;GO:0071492//cellular response to UV-A;GO:0071345//cellular response to cytokine stimulus;GO:0019233//sensory perception of pain,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0042277//peptide binding;GO:0004175//endopeptidase activity,K01389//Protein digestion and absorption;Alzheimer's disease;Hematopoietic cell lineage;Renin-angiotensin system
4312,0,0,0,0,0,18,0,0,0,0,0,0,MMP1;matrix metallopeptidase 1 (interstitial collagenase),GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0016032//viral process;GO:0022617//extracellular matrix disassembly;GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0030574//collagen catabolic process;GO:0006508//proteolysis;GO:0044267//cellular protein metabolic process,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K01388//Rheumatoid arthritis;PPAR signaling pathway;Pathways in cancer;Bladder cancer
4313,0,0,0,0,0,12,0,0,44,0,0,0,"MMP2;matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)",GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0030017//sarcomere;GO:0005634//nucleus,GO:0007566//embryo implantation;GO:0001955//blood vessel maturation;GO:0006508//proteolysis;GO:0060325//face morphogenesis;GO:0044267//cellular protein metabolic process;GO:0035987//endodermal cell differentiation;GO:0060346//bone trabecula formation;GO:0001666//response to hypoxia;GO:0045089//positive regulation of innate immune response;GO:0030574//collagen catabolic process;GO:0001957//intramembranous ossification;GO:0001525//angiogenesis;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004252//serine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity,K01398//Leukocyte transendothelial migration;Bladder cancer;Pathways in cancer;GnRH signaling pathway
4314,0,0,0,0,0,19,0,0,34,0,0,0,"MMP3;matrix metallopeptidase 3 (stromelysin 1, progelatinase)",GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0030334//regulation of cell migration;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0010727//negative regulation of hydrogen peroxide metabolic process;GO:0030574//collagen catabolic process;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0004175//endopeptidase activity,K01394//Rheumatoid arthritis;Transcriptional misregulation in cancer
4316,0,0,0,0,0,0,11,0,9,0,0,0,"MMP7;matrix metallopeptidase 7 (matrilysin, uterine)",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0050829//defense response to Gram-negative bacterium;GO:0022617//extracellular matrix disassembly;GO:0042493//response to drug;GO:0042127//regulation of cell proliferation;GO:0050830//defense response to Gram-positive bacterium;GO:0030198//extracellular matrix organization;GO:0006508//proteolysis;GO:0030574//collagen catabolic process;GO:0002779//antibacterial peptide secretion,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,K01397//Wnt signaling pathway
4317,0,0,0,0,0,0,49,0,8,0,20,0,MMP8;matrix metallopeptidase 8 (neutrophil collagenase),GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization;GO:0035987//endodermal cell differentiation;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
431704,0,0,0,0,0,0,0,0,2,0,0,0,RGS21;regulator of G-protein signaling 21,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K07524//Axon guidance
431705,0,0,0,0,0,2,0,1,20,0,0,0,ASTL;astacin-like metallo-endopeptidase (M12 family),GO:0005737//cytoplasm;GO:0060473//cortical granule;GO:0030133//transport vesicle;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0010954//positive regulation of protein processing;GO:0009566//fertilization;GO:0006508//proteolysis;GO:0060468//prevention of polyspermy;GO:2000360//negative regulation of binding of sperm to zona pellucida,GO:0070001//aspartic-type peptidase activity;GO:0008233//peptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0070002//glutamic-type peptidase activity,-
431707,8,0,0,0,0,0,0,124,28,0,0,0,LHX8;LIM homeobox 8,GO:0001674//female germ cell nucleus,"GO:0007611//learning or memory;GO:0006355//regulation of transcription, DNA-templated;GO:0021884//forebrain neuron development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0006351//transcription, DNA-templated;GO:0008585//female gonad development",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding,-
4318,0,0,26,0,0,0,23,0,21,6,0,0,"MMP9;matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0001501//skeletal system development;GO:0051549//positive regulation of keratinocyte migration;GO:0030574//collagen catabolic process;GO:0030225//macrophage differentiation;GO:0006508//proteolysis;GO:0007566//embryo implantation;GO:0035987//endodermal cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0030198//extracellular matrix organization;GO:1900122//positive regulation of receptor binding;GO:0001503//ossification;GO:0022617//extracellular matrix disassembly;GO:0050900//leukocyte migration;GO:2001258//negative regulation of cation channel activity,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding;GO:0005518//collagen binding;GO:0004222//metalloendopeptidase activity,K01403//Pathways in cancer;Leukocyte transendothelial migration;Bladder cancer;Transcriptional misregulation in cancer
4319,0,0,0,0,0,0,19,0,18,0,15,0,MMP10;matrix metallopeptidase 10 (stromelysin 2),GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0030334//regulation of cell migration;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K01394//Rheumatoid arthritis;Transcriptional misregulation in cancer
432,61,0,0,0,0,0,0,0,44,0,0,0,ASGR1;asialoglycoprotein receptor 1,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0031668//cellular response to extracellular stimulus;GO:0006898//receptor-mediated endocytosis,GO:0004873//asialoglycoprotein receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0030246//carbohydrate binding,-
4320,0,0,0,0,0,40,0,124,46,0,0,0,MMP11;matrix metallopeptidase 11 (stromelysin 3),GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005796//Golgi lumen;GO:0005576//extracellular region,GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0007275//multicellular organismal development;GO:0045599//negative regulation of fat cell differentiation;GO:0071711//basement membrane organization;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
4321,0,0,0,0,0,0,0,0,13,0,0,0,MMP12;matrix metallopeptidase 12 (macrophage elastase),GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,"GO:0030198//extracellular matrix organization;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0035313//wound healing, spreading of epidermal cells",GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,-
4322,0,0,0,0,0,19,0,0,33,0,0,0,MMP13;matrix metallopeptidase 13 (collagenase 3),GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0051216//cartilage development;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0001958//endochondral ossification;GO:0044267//cellular protein metabolic process;GO:0030282//bone mineralization;GO:0006508//proteolysis;GO:0030574//collagen catabolic process;GO:0060349//bone morphogenesis,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005518//collagen binding;GO:0004222//metalloendopeptidase activity,-
4323,0,0,0,0,3,0,0,53,38,0,4,0,MMP14;matrix metallopeptidase 14 (membrane-inserted),GO:0005887//integral component of plasma membrane;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0042470//melanosome;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005925//focal adhesion,"GO:0051895//negative regulation of focal adhesion assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0001525//angiogenesis;GO:0030198//extracellular matrix organization;GO:0001935//endothelial cell proliferation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0043615//astrocyte cell migration;GO:0030335//positive regulation of cell migration;GO:0035987//endodermal cell differentiation;GO:0031638//zymogen activation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030307//positive regulation of cell growth;GO:0035988//chondrocyte proliferation;GO:0048771//tissue remodeling;GO:0097094//craniofacial suture morphogenesis;GO:0001958//endochondral ossification;GO:0022617//extracellular matrix disassembly;GO:0006979//response to oxidative stress;GO:0043627//response to estrogen;GO:0006508//proteolysis;GO:0010952//positive regulation of peptidase activity;GO:0008584//male gonad development;GO:0009612//response to mechanical stimulus;GO:0001666//response to hypoxia;GO:0030324//lung development;GO:0030574//collagen catabolic process;GO:0001541//ovarian follicle development",GO:0005515//protein binding;GO:0005178//integrin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0016504//peptidase activator activity,K07763//GnRH signaling pathway
4324,0,20,0,0,0,20,7,3,52,108,0,280,MMP15;matrix metallopeptidase 15 (membrane-inserted),GO:0005887//integral component of plasma membrane;GO:0031012//extracellular matrix;GO:0005886//plasma membrane,GO:0043085//positive regulation of catalytic activity;GO:0030574//collagen catabolic process;GO:0006508//proteolysis;GO:0035987//endodermal cell differentiation;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0006464//cellular protein modification process;GO:0032355//response to estradiol,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008047//enzyme activator activity;GO:0004222//metalloendopeptidase activity,-
4325,168,0,0,0,0,0,0,0,52,0,1,0,MMP16;matrix metallopeptidase 16 (membrane-inserted),GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005796//Golgi lumen;GO:0009986//cell surface,GO:0030574//collagen catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0006508//proteolysis;GO:0022617//extracellular matrix disassembly;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0030198//extracellular matrix organization;GO:0097094//craniofacial suture morphogenesis;GO:0001958//endochondral ossification;GO:0035988//chondrocyte proliferation,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity,-
4326,0,0,0,0,0,39,0,0,4,64,0,0,MMP17;matrix metallopeptidase 17 (membrane-inserted),GO:0005578//proteinaceous extracellular matrix;GO:0005887//integral component of plasma membrane;GO:0031225//anchored component of membrane,GO:0043085//positive regulation of catalytic activity;GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008047//enzyme activator activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,-
4327,1,301,152,191,387,0,0,74,78,270,342,0,MMP19;matrix metallopeptidase 19,GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region,GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly;GO:0051591//response to cAMP;GO:0030198//extracellular matrix organization;GO:0001525//angiogenesis;GO:0001542//ovulation from ovarian follicle;GO:0009725//response to hormone;GO:0001541//ovarian follicle development;GO:0030574//collagen catabolic process;GO:0001554//luteolysis;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
4329,0,120,118,184,356,64,0,1,19,0,23,347,"ALDH6A1;aldehyde dehydrogenase 6 family, member A1",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0006210//thymine catabolic process;GO:0006573//valine metabolic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0055114//oxidation-reduction process;GO:0050873//brown fat cell differentiation;GO:0009083//branched-chain amino acid catabolic process;GO:0006574//valine catabolic process,GO:0000062//fatty-acyl-CoA binding;GO:0018478//malonate-semialdehyde dehydrogenase (acetylating) activity;GO:0004491//methylmalonate-semialdehyde dehydrogenase (acylating) activity;GO:0044822//poly(A) RNA binding,"K00140//Propanoate metabolism;Metabolic pathways;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Inositol phosphate metabolism"
433,0,0,0,0,0,20,11,0,3,0,4,0,ASGR2;asialoglycoprotein receptor 2,GO:0016021//integral component of membrane,GO:0006898//receptor-mediated endocytosis;GO:0009100//glycoprotein metabolic process;GO:0007166//cell surface receptor signaling pathway;GO:0055088//lipid homeostasis;GO:0031647//regulation of protein stability;GO:0030282//bone mineralization,GO:0004873//asialoglycoprotein receptor activity;GO:0030246//carbohydrate binding;GO:0005515//protein binding,-
4330,0,0,0,0,2,17,61,67,38,0,4,0,MN1;meningioma (disrupted in balanced translocation) 1,-,GO:0001957//intramembranous ossification,-,-
4331,0,0,0,27,23,0,0,0,45,0,0,0,MNAT1;MNAT CDK-activating kinase assembly factor 1,GO:0005654//nucleoplasm;GO:0005675//holo TFIIH complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0007512//adult heart development;GO:0006281//DNA repair;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0021591//ventricular system development;GO:0006200//ATP catabolic process;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0051592//response to calcium ion;GO:0006468//protein phosphorylation;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006461//protein complex assembly;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0008283//cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process",GO:0008094//DNA-dependent ATPase activity;GO:0047485//protein N-terminus binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,K10842//Nucleotide excision repair;Basal transcription factors
4332,0,0,0,0,0,1,44,3,8,0,6,0,MNDA;myeloid cell nuclear differentiation antigen,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0030889//negative regulation of B cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0006968//cellular defense response;GO:0050853//B cell receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding,K12966//Cytosolic DNA-sensing pathway
4335,0,1,0,0,0,0,0,0,0,0,0,0,MNT;MAX network transcriptional repressor,GO:0005634//nucleus,GO:0007569//cell aging;GO:0006366//transcription from RNA polymerase II promoter;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051726//regulation of cell cycle,GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0046983//protein dimerization activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
4336,0,0,0,0,0,42,13,0,0,56,0,0,MOBP;myelin-associated oligodendrocyte basic protein,GO:0048471//perinuclear region of cytoplasm,GO:0006886//intracellular protein transport;GO:0007399//nervous system development,GO:0017137//Rab GTPase binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
4337,0,0,0,0,0,0,55,0,25,0,13,315,MOCS1;molybdenum cofactor synthesis 1,GO:0019008//molybdopterin synthase complex;GO:0005634//nucleus;GO:0005829//cytosol,GO:0006766//vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,"GO:0005525//GTP binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0046872//metal ion binding",K03639//Metabolic pathways;Folate biosynthesis;Sulfur relay system
4338,15,6,21,112,259,21,0,0,20,0,0,0,MOCS2;molybdenum cofactor synthesis 2,GO:0019008//molybdopterin synthase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006766//vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0042802//identical protein binding;GO:0030366//molybdopterin synthase activity;GO:0000166//nucleotide binding,K03635//Folate biosynthesis;Sulfur relay system;Metabolic pathways
434,0,0,0,0,0,0,0,0,10,0,0,0,ASIP;agouti signaling protein,GO:0005615//extracellular space,"GO:0008343//adult feeding behavior;GO:0006091//generation of precursor metabolites and energy;GO:0032438//melanosome organization;GO:0007267//cell-cell signaling;GO:0042438//melanin biosynthetic process;GO:0007165//signal transduction;GO:0071514//genetic imprinting;GO:0009755//hormone-mediated signaling pathway;GO:0032402//melanosome transport;GO:0040030//regulation of molecular function, epigenetic",GO:0031781//type 3 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0005102//receptor binding,K08725//Melanogenesis
4342,0,0,0,0,0,0,22,0,0,0,0,0,MOS;v-mos Moloney murine sarcoma viral oncogene homolog,GO:0005737//cytoplasm,GO:0000212//meiotic spindle organization;GO:0046777//protein autophosphorylation;GO:1902103//negative regulation of metaphase/anaphase transition of meiotic cell cycle;GO:0000165//MAPK cascade;GO:0000187//activation of MAPK activity;GO:0000186//activation of MAPKK activity;GO:0051296//establishment of meiotic spindle orientation;GO:0006325//chromatin organization;GO:0040020//regulation of meiosis,GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K04367//Progesterone-mediated oocyte maturation;Oocyte meiosis;Regulation of actin cytoskeleton;MAPK signaling pathway
4343,198,0,20,25,13,14,3,26,12,0,18,312,MOV10;Mov10 RISC complex RNA helicase,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0000932//cytoplasmic mRNA processing body,"GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0007219//Notch signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0035279//mRNA cleavage involved in gene silencing by miRNA;GO:0045087//innate immune response;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006351//transcription, DNA-templated",GO:0004386//helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
435,41,0,0,0,1,29,0,6,17,136,0,0,ASL;argininosuccinate lyase,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000050//urea cycle;GO:0042450//arginine biosynthetic process via ornithine;GO:0006527//arginine catabolic process;GO:0006475//internal protein amino acid acetylation,GO:0004056//argininosuccinate lyase activity,"K01755//Arginine and proline metabolism;Two-component system;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Galactose metabolism;Glycolysis / Gluconeogenesis;Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Biosynthesis of secondary metabolites;Folate biosynthesis;Streptomycin biosynthesis;Microbial metabolism in diverse environments"
4350,0,0,0,8,27,0,8,0,0,0,6,0,MPG;N-methylpurine-DNA glycosylase,GO:0042645//mitochondrial nucleoid;GO:0005654//nucleoplasm,GO:0006307//DNA dealkylation involved in DNA repair;GO:0006281//DNA repair;GO:0045007//depurination;GO:0006284//base-excision repair,GO:0052822//DNA-3-methylguanine glycosylase activity;GO:0003684//damaged DNA binding;GO:0043916//DNA-7-methylguanine glycosylase activity;GO:0052821//DNA-7-methyladenine glycosylase activity;GO:0008725//DNA-3-methyladenine glycosylase activity;GO:0005515//protein binding,K03652//Phosphotransferase system (PTS);Amino sugar and nucleotide sugar metabolism;Base excision repair
4351,0,1,41,0,52,0,0,0,0,0,5,0,MPI;mannose phosphate isomerase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0009298//GDP-mannose biosynthetic process,GO:0004476//mannose-6-phosphate isomerase activity;GO:0008270//zinc ion binding,K01809//Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Fructose and mannose metabolism;Other glycan degradation;Galactose metabolism;Citrate cycle (TCA cycle);Metabolic pathways;Sphingolipid metabolism
4352,40,0,0,0,8,0,15,0,36,0,0,0,"MPL;MPL proto-oncogene, thrombopoietin receptor",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0048872//homeostasis of number of cells;GO:0019221//cytokine-mediated signaling pathway;GO:0030168//platelet activation;GO:0032642//regulation of chemokine production;GO:0007166//cell surface receptor signaling pathway;GO:0008283//cell proliferation;GO:0007596//blood coagulation,GO:0004896//cytokine receptor activity;GO:0004888//transmembrane signaling receptor activity,K05082//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
4353,0,0,0,0,0,2,0,0,17,0,21,0,MPO;myeloperoxidase,GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0042582//azurophil granule;GO:0005634//nucleus,GO:0019430//removal of superoxide radicals;GO:0044130//negative regulation of growth of symbiont in host;GO:0002149//hypochlorous acid biosynthetic process;GO:0042744//hydrogen peroxide catabolic process;GO:0006952//defense response;GO:0043066//negative regulation of apoptotic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0032094//response to food;GO:0050832//defense response to fungus;GO:0032496//response to lipopolysaccharide;GO:0002679//respiratory burst involved in defense response;GO:0007568//aging;GO:0006979//response to oxidative stress;GO:0001878//response to yeast;GO:0009612//response to mechanical stimulus;GO:0055114//oxidation-reduction process,GO:0008201//heparin binding;GO:0046872//metal ion binding;GO:0004601//peroxidase activity;GO:0020037//heme binding;GO:0003682//chromatin binding,K10789//Phagosome;Transcriptional misregulation in cancer
4354,0,0,0,1,7,0,46,0,0,0,0,0,"MPP1;membrane protein, palmitoylated 1, 55kDa",GO:0016020//membrane;GO:0030863//cortical cytoskeleton;GO:0005622//intracellular;GO:0005887//integral component of plasma membrane;GO:0032420//stereocilium,GO:0046939//nucleotide phosphorylation;GO:0007165//signal transduction;GO:0090022//regulation of neutrophil chemotaxis,GO:0004385//guanylate kinase activity;GO:0005515//protein binding,K06103//Tight junction
4355,63,0,0,0,6,0,0,89,23,0,0,2,"MPP2;membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)",GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0007165//signal transduction;GO:0046939//nucleotide phosphorylation,GO:0004385//guanylate kinase activity,K06103//Tight junction
4356,0,1,30,0,0,6,0,0,19,0,20,0,"MPP3;membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)",GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0046939//nucleotide phosphorylation,GO:0004385//guanylate kinase activity;GO:0030165//PDZ domain binding,K06091//Tight junction
4357,0,0,0,4,0,0,0,0,15,0,10,0,MPST;mercaptopyruvate sulfurtransferase,GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0005743//mitochondrial inner membrane;GO:0030054//cell junction,GO:0009636//response to toxic substance;GO:0070814//hydrogen sulfide biosynthetic process;GO:0009440//cyanate catabolic process,GO:0004792//thiosulfate sulfurtransferase activity;GO:0016784//3-mercaptopyruvate sulfurtransferase activity,K01011//Metabolic pathways;Sulfur relay system;Cysteine and methionine metabolism
4358,0,0,0,1,0,21,0,0,0,0,0,0,MPV17;MpV17 mitochondrial inner membrane protein,GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0048839//inner ear development;GO:0034614//cellular response to reactive oxygen species;GO:0072593//reactive oxygen species metabolic process;GO:0000002//mitochondrial genome maintenance;GO:0042592//homeostatic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0032836//glomerular basement membrane development,-,K13348//Peroxisome
4359,2,0,0,0,0,0,27,41,16,0,1,0,MPZ;myelin protein zero,GO:0005887//integral component of plasma membrane;GO:0043209//myelin sheath;GO:0005886//plasma membrane,GO:0008219//cell death;GO:0007268//synaptic transmission;GO:0045217//cell-cell junction maintenance,GO:0005198//structural molecule activity,K06770//Cell adhesion molecules (CAMs)
4360,75,0,0,0,0,9,0,0,74,0,0,0,"MRC1;mannose receptor, C type 1",GO:0010008//endosome membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction,GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005537//mannose binding;GO:0005515//protein binding,K06560//Phagosome;Tuberculosis
4361,2,45,0,29,60,34,17,0,62,0,18,0,MRE11A;MRE11 meiotic recombination 11 homolog A (S. cerevisiae),"GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0035861//site of double-strand break;GO:0030870//Mre11 complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus","GO:0000019//regulation of mitotic recombination;GO:0032508//DNA duplex unwinding;GO:0008283//cell proliferation;GO:0000723//telomere maintenance;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007004//telomere maintenance via telomerase;GO:0031573//intra-S DNA damage checkpoint;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0007131//reciprocal meiotic recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0000724//double-strand break repair via homologous recombination;GO:0007129//synapsis;GO:0031954//positive regulation of protein autophosphorylation;GO:0007062//sister chromatid cohesion;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair;GO:0006281//DNA repair;GO:0032876//negative regulation of DNA endoreduplication;GO:0006310//DNA recombination;GO:0033674//positive regulation of kinase activity;GO:0006302//double-strand break repair;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus",GO:0004003//ATP-dependent DNA helicase activity;GO:0008408//3'-5' exonuclease activity;GO:0004520//endodeoxyribonuclease activity;GO:0003677//DNA binding;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0030145//manganese ion binding;GO:0003690//double-stranded DNA binding;GO:0004518//nuclease activity;GO:0008022//protein C-terminus binding;GO:0004519//endonuclease activity;GO:0005515//protein binding,K10865//Homologous recombination;Non-homologous end-joining
4363,0,0,0,0,20,0,0,0,66,0,68,0,"ABCC1;ATP-binding cassette, sub-family C (CFTR/MRP), member 1",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0009235//cobalamin metabolic process;GO:0042493//response to drug;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006691//leukotriene metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0006810//transport;GO:0006766//vitamin metabolic process;GO:0055085//transmembrane transport,"GO:0005524//ATP binding;GO:0005215//transporter activity;GO:0016887//ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05665//Vitamin digestion and absorption;ABC transporters
438,11,0,0,0,0,0,0,0,4,0,0,0,ASMT;acetylserotonin O-methyltransferase,GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0032259//methylation;GO:0006412//translation;GO:0030187//melatonin biosynthetic process;GO:2000019//negative regulation of male gonad development;GO:0046219//indolalkylamine biosynthetic process,GO:0008171//O-methyltransferase activity;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0017096//acetylserotonin O-methyltransferase activity,K00543//Metabolic pathways;Tryptophan metabolism
43847,0,0,0,0,0,4,0,27,61,13,0,0,KLK14;kallikrein-related peptidase 14,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0009566//fertilization;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0048730//epidermis morphogenesis;GO:0006508//proteolysis;GO:0070684//seminal clot liquefaction;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway,GO:0004252//serine-type endopeptidase activity,-
43849,0,0,0,0,0,0,0,0,15,0,0,0,KLK12;kallikrein-related peptidase 12,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
439,0,0,0,0,2,0,0,131,8,0,0,0,"ASNA1;arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0015698//inorganic anion transport;GO:0006810//transport;GO:0045048//protein insertion into ER membrane;GO:0006200//ATP catabolic process,GO:0046872//metal ion binding;GO:0015105//arsenite transmembrane transporter activity;GO:0016887//ATPase activity;GO:0005215//transporter activity;GO:0005524//ATP binding,-
439915,11,0,0,0,0,0,0,0,0,1,0,0,KRTAP5-5;keratin associated protein 5-5,GO:0045095//keratin filament,-,-,-
439921,19,10,0,0,70,0,5,0,36,0,0,0,MXRA7;matrix-remodelling associated 7,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
439931,0,0,40,3,73,30,0,0,19,0,88,0,THAP7-AS1;THAP7 antisense RNA 1,-,-,-,K07374//Pathogenic Escherichia coli infection;Phagosome;Gap junction
439965,0,0,0,0,0,1,0,0,0,0,0,0,"FAM35DP;family with sequence similarity 35, member A pseudogene",-,-,-,-
439996,0,0,0,0,0,0,0,0,51,0,0,0,IFIT1B;interferon-induced protein with tetratricopeptide repeats 1B,-,-,-,K14217//Hepatitis C;Herpes simplex infection
440,0,0,0,0,7,0,78,0,21,0,0,0,ASNS;asparagine synthetase (glutamine-hydrolyzing),GO:0005829//cytosol,GO:0042149//cellular response to glucose starvation;GO:0043066//negative regulation of apoptotic process;GO:0006541//glutamine metabolic process;GO:0031427//response to methotrexate;GO:0045931//positive regulation of mitotic cell cycle;GO:0001889//liver development;GO:0009636//response to toxic substance;GO:0044281//small molecule metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0008652//cellular amino acid biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0043200//response to amino acid;GO:0032354//response to follicle-stimulating hormone;GO:0006529//asparagine biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0009416//response to light stimulus;GO:0032870//cellular response to hormone stimulus;GO:0070981//L-asparagine biosynthetic process;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0048037//cofactor binding,"K01953//Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Nitrogen metabolism;Biosynthesis of secondary metabolites"
440021,0,0,0,0,0,0,0,0,25,0,0,0,KRTAP5-2;keratin associated protein 5-2,GO:0045095//keratin filament,-,-,-
440023,0,0,0,0,0,0,0,56,0,0,0,0,KRTAP5-6;keratin associated protein 5-6,GO:0045095//keratin filament,-,-,-
440026,0,0,0,0,0,3,20,0,29,0,0,0,TMEM41B;transmembrane protein 41B,GO:0016021//integral component of membrane,GO:0007399//nervous system development,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
440040,0,0,0,0,0,0,0,59,18,0,0,0,"LOC440040;glutamate receptor, metabotropic 5 pseudogene",-,-,-,K04604//Glutamatergic synapse;Neuroactive ligand-receptor interaction;Long-term potentiation;Retrograde endocannabinoid signaling;Calcium signaling pathway;Long-term depression;Huntington's disease;Gap junction
440041,0,0,0,0,0,0,37,0,0,0,0,0,"TRIM51HP;tripartite motif-containing 51H, pseudogene",-,-,-,-
440044,176,0,0,0,0,25,52,0,39,11,10,526,"SLC22A20;solute carrier family 22, member 20",GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,-
440051,0,0,0,0,0,0,0,0,29,0,0,0,KRTAP5-11;keratin associated protein 5-11,GO:0045095//keratin filament,-,-,-
440068,0,0,0,0,0,0,0,0,24,0,0,0,"CARD17;caspase recruitment domain family, member 17",GO:0005737//cytoplasm,GO:0010951//negative regulation of endopeptidase activity;GO:0042981//regulation of apoptotic process,GO:0004869//cysteine-type endopeptidase inhibitor activity,K01370//Cytosolic DNA-sensing pathway;Salmonella infection;Amyotrophic lateral sclerosis (ALS);Legionellosis;Pertussis;NOD-like receptor signaling pathway;Influenza A
440072,0,0,55,0,20,41,0,0,5,0,56,0,LINC00167;long intergenic non-protein coding RNA 167,-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
440073,67,0,0,0,0,25,1,0,32,0,1,0,IQSEC3;IQ motif and Sec7 domain 3,GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0060077//inhibitory synapse;GO:0005802//trans-Golgi network,GO:0043547//positive regulation of GTPase activity;GO:0032012//regulation of ARF protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization,GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
440077,0,0,0,0,0,3,0,0,5,0,15,0,ZNF705A;zinc finger protein 705A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
440081,144,0,3,0,0,1,8,46,3,128,0,0,"DDX12P;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene",GO:0005634//nucleus,GO:0032508//DNA duplex unwinding;GO:0006200//ATP catabolic process;GO:0007049//cell cycle,GO:0003677//DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0003723//RNA binding;GO:0005524//ATP binding,-
440087,0,0,0,17,29,14,0,0,0,0,0,0,SMCO3;single-pass membrane protein with coiled-coil domains 3,GO:0016021//integral component of membrane,-,-,-
440093,0,0,0,0,0,0,0,0,3,0,0,0,"H3F3C;H3 histone, family 3C",GO:0005719//nuclear euchromatin;GO:0000786//nucleosome,GO:0030307//positive regulation of cell growth,GO:0046982//protein heterodimerization activity;GO:0031492//nucleosomal DNA binding,K11253//Alcoholism;Transcriptional misregulation in cancer;Systemic lupus erythematosus
440097,0,0,0,0,0,0,34,9,4,0,0,0,DBX2;developing brain homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
440104,0,0,0,0,14,0,0,0,0,0,0,0,"TMEM198B;transmembrane protein 198B, pseudogene",-,-,-,-
440107,0,0,0,0,0,0,31,0,45,0,24,0,"PLEKHG7;pleckstrin homology domain containing, family G (with RhoGef domain) member 7",-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12331//Vascular smooth muscle contraction;K07532//Tuberculosis;Axon guidance;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
440132,0,0,0,0,0,0,0,0,8,0,0,0,LINC00545;long intergenic non-protein coding RNA 545,-,-,-,-
440138,116,0,0,0,0,5,0,0,0,0,0,0,"ALG11;ALG11, alpha-1,2-mannosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0097502//mannosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification,"GO:0004377//GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity",K14567//Ribosome biogenesis in eukaryotes;K03844//Metabolic pathways;Various types of N-glycan biosynthesis;N-Glycan biosynthesis
440145,0,0,0,18,14,0,0,0,2,0,5,0,MZT1;mitotic spindle organizing protein 1,GO:0008274//gamma-tubulin ring complex;GO:0005819//spindle;GO:0005813//centrosome,GO:0033566//gamma-tubulin complex localization,GO:0005515//protein binding,-
440153,0,0,0,0,0,0,19,0,3,0,0,0,"OR11H12;olfactory receptor, family 11, subfamily H, member 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
440163,38,0,0,0,0,0,0,0,35,0,0,0,"RNASE13;ribonuclease, RNase A family, 13 (non-active)",GO:0005576//extracellular region,-,GO:0003676//nucleic acid binding,-
440184,0,0,0,0,0,0,70,0,25,0,0,0,LINC00238;long intergenic non-protein coding RNA 238,-,-,-,K12478//Tuberculosis;Phagosome;Endocytosis
440193,0,2,1,10,60,30,103,0,96,0,26,0,CCDC88C;coiled-coil domain containing 88C,-,GO:0016055//Wnt signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0031648//protein destabilization;GO:0051260//protein homooligomerization,GO:0043621//protein self-association;GO:0030165//PDZ domain binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
440224,0,0,0,0,0,0,20,0,0,0,6,0,CXADRP3;coxsackie virus and adenovirus receptor pseudogene 3,-,-,-,K06788//Viral myocarditis
440225,67,0,0,0,0,0,48,0,41,0,0,0,NF1P2;neurofibromin 1 pseudogene 2,-,-,-,K08052//MAPK signaling pathway
440243,3,0,0,4,0,12,0,0,25,1,0,1,GOLGA6L22;golgin A6 family-like 22,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation
440248,0,27,1,0,0,0,0,0,91,0,0,8,HERC2P9;hect domain and RLD 2 pseudogene 9,-,-,-,K10595//Ubiquitin mediated proteolysis
440253,0,0,0,0,0,0,0,0,12,0,0,0,"WHAMMP2;WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 2",-,-,-,K11447//Transcriptional misregulation in cancer
440270,0,0,0,0,0,0,16,0,10,1,6,1,"GOLGA8B;golgin A8 family, member B",GO:0032580//Golgi cisterna membrane,-,-,K10582//Ubiquitin mediated proteolysis;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K06102//Tight junction
440275,83,16,165,156,173,49,34,74,93,0,81,0,EIF2AK4;eukaryotic translation initiation factor 2 alpha kinase 4,GO:0022626//cytosolic ribosome,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0017148//negative regulation of translation;GO:0009267//cellular response to starvation;GO:0043558//regulation of translational initiation in response to stress;GO:0006468//protein phosphorylation;GO:0006446//regulation of translational initiation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0042803//protein homodimerization activity,K08860//Hepatitis C;Alzheimer's disease;Protein processing in endoplasmic reticulum;Herpes simplex infection;Influenza A;Epstein-Barr virus infection;Measles
440278,1,0,0,0,0,0,0,0,0,0,0,0,"CATSPER2P1;cation channel, sperm associated 2 pseudogene 1",-,-,-,K00797//beta-Alanine metabolism;Metabolic pathways;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K14443//RNA degradation
440279,0,0,0,0,0,23,19,0,24,0,0,0,UNC13C;unc-13 homolog C (C. elegans),GO:0005737//cytoplasm;GO:0048786//presynaptic active zone;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0006887//exocytosis;GO:0035556//intracellular signal transduction;GO:0007268//synaptic transmission,GO:0046872//metal ion binding;GO:0019992//diacylglycerol binding,K15293//Synaptic vesicle cycle
440295,0,0,0,0,0,1,0,0,0,7,0,0,GOLGA6L9;golgin A6 family-like 9,-,-,-,-
440299,0,1,0,0,0,0,2,0,14,0,2,2,DNM1P41;DNM1 pseudogene 41,-,-,-,K01528//Endocytosis;Bacterial invasion of epithelial cells;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Synaptic vesicle cycle
440300,0,465,145,249,221,1,2,1254,126,0,765,1,LOC440300;chondroitin sulfate proteoglycan 4 pseudogene,-,-,-,-
440307,103,0,0,0,0,0,1,0,14,0,0,0,"TTLL13;tubulin tyrosine ligase-like family, member 13",-,GO:0006464//cellular protein modification process,GO:0016874//ligase activity,"K00273//Peroxisome;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism;Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism;Metabolic pathways"
440311,0,0,0,0,0,0,0,0,3,0,0,0,LOC440311;glioma tumor suppressor candidate region gene 2 pseudogene,-,-,-,K14840//Herpes simplex infection
440335,0,0,0,0,0,18,0,0,13,0,0,0,SMIM22;small integral membrane protein 22,GO:0016021//integral component of membrane,-,-,-
440352,0,0,0,0,0,0,1,26,9,118,0,0,SNX29P2;sorting nexin 29 pseudogene 2,-,-,-,K15348//Salmonella infection
440354,0,0,0,0,1,0,0,1,2,0,12,0,SMG1P2;SMG1 pseudogene 2,-,-,-,K08873//mRNA surveillance pathway
440356,0,0,0,0,0,0,0,0,3,0,0,0,CDIPT-AS1;CDIPT antisense RNA 1 (head to head),-,-,-,-
440359,0,0,0,0,0,0,0,0,0,0,0,243,YBX3P1;Y box binding protein 3 pseudogene 1,-,-,-,K06099//Tight junction
440387,0,0,0,0,0,12,0,0,0,0,0,0,CTRB2;chymotrypsinogen B2,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007586//digestion;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0009235//cobalamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006766//vitamin metabolic process;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01310//Protein digestion and absorption;Pancreatic secretion
440400,0,22,0,0,12,0,0,0,0,0,0,0,"RNASEK;ribonuclease, RNase K",GO:0016021//integral component of membrane,"GO:0009303//rRNA transcription;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0004521//endoribonuclease activity,-
440419,0,0,0,0,0,8,0,60,26,0,8,0,"TBC1D3P5;TBC1 domain family, member 3 pseudogene 5",-,-,-,-
440434,0,18,0,16,29,1,0,0,36,0,37,0,LOC440434;aminopeptidase puromycin sensitive pseudogene,GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity,-
440435,97,0,0,0,0,46,60,1,109,0,7,265,GPR179;G protein-coupled receptor 179,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007601//visual perception;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
440446,0,0,0,0,0,0,0,0,9,0,0,0,LOC440446;uncharacterized LOC440446,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
440452,15,0,0,0,0,8,0,0,19,0,0,0,"TBC1D3P2;TBC1 domain family, member 3 pseudogene 2",-,-,-,-
440456,0,0,0,0,0,0,0,0,0,156,11,0,"PLEKHM1P;pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene",-,GO:0035556//intracellular signal transduction,GO:0046872//metal ion binding,-
440461,0,0,0,0,0,0,16,0,18,0,0,0,LOC440461;Rho GTPase activating protein 27 pseudogene,-,-,-,-
440465,0,12,1,0,28,42,0,0,31,0,4,493,BAIAP2-AS1;BAIAP2 antisense RNA 1 (head to head),-,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
440482,0,0,0,0,0,0,0,0,35,66,0,0,"ANKRD20A5P;ankyrin repeat domain 20 family, member A5, pseudogene",-,-,-,-
440498,0,0,0,0,0,23,0,0,0,0,0,0,HSBP1L1;heat shock factor binding protein 1-like 1,-,-,-,-
440503,24,0,0,0,0,0,0,0,15,0,0,0,PLIN5;perilipin 5,GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005811//lipid particle;GO:0005829//cytosol,GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0034389//lipid particle organization;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0019915//lipid storage;GO:0051646//mitochondrion localization;GO:0031999//negative regulation of fatty acid beta-oxidation;GO:0060193//positive regulation of lipase activity;GO:0010890//positive regulation of sequestering of triglyceride;GO:0010884//positive regulation of lipid storage;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0060192//negative regulation of lipase activity;GO:0010897//negative regulation of triglyceride catabolic process,GO:0042802//identical protein binding;GO:0035473//lipase binding,K08768//PPAR signaling pathway
440508,0,0,0,0,18,0,0,0,15,0,0,0,"CLEC4GP1;C-type lectin domain family 4, member G pseudogene 1",-,-,-,-
440515,0,0,0,7,32,24,0,0,18,0,0,0,ZNF506;zinc finger protein 506,GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
440518,0,0,0,0,0,16,0,0,0,0,11,0,GOLGA2P9;golgin A2 pseudogene 9,-,-,-,-
440533,91,0,0,0,0,0,0,0,0,0,0,0,PSG8;pregnancy specific beta-1-glycoprotein 8,GO:0005576//extracellular region,-,-,-
440560,0,0,0,0,0,26,50,0,5,0,0,5,PRAMEF11;PRAME family member 11,-,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation",GO:0042974//retinoic acid receptor binding,-
440563,0,0,0,0,0,0,0,0,10,0,0,0,HNRNPCL2;heterogeneous nuclear ribonucleoprotein C-like 2,-,-,-,K12884//Spliceosome
440567,0,1,0,0,1,0,0,0,3,0,0,0,UQCRHL;ubiquinol-cytochrome c reductase hinge protein-like,-,-,-,K00416//Cardiac muscle contraction;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
440574,0,27,1,57,93,0,47,58,12,0,0,0,MINOS1;mitochondrial inner membrane organizing system 1,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
440590,0,9,0,0,1,0,1,0,29,0,5,1,"ZYG11A;zyg-11 family member A, cell cycle regulator",-,-,-,-
440602,0,0,0,0,0,0,0,48,0,0,0,0,LOC440602;uncharacterized LOC440602,-,-,-,-
440603,35,0,0,0,0,0,0,0,0,0,0,0,BCL2L15;BCL2-like 15,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006915//apoptotic process,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
440689,0,0,0,0,13,0,0,0,11,0,0,0,"HIST2H2BF;histone cluster 2, H2bf",GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006325//chromatin organization,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Alcoholism;Systemic lupus erythematosus
440695,0,0,0,0,0,29,1,51,0,0,0,0,ETV3L;ets variant 3-like,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding,-
440712,0,0,0,0,0,0,15,0,69,0,0,0,C1orf186;chromosome 1 open reading frame 186,GO:0016021//integral component of membrane,-,-,K02872//Ribosome
440730,0,0,0,0,0,0,0,37,0,0,0,0,TRIM67;tripartite motif containing 67,GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0010976//positive regulation of neuron projection development;GO:0046580//negative regulation of Ras protein signal transduction,GO:0008270//zinc ion binding,-
440738,0,0,0,0,0,0,5,0,11,0,0,0,MAP1LC3C;microtubule-associated protein 1 light chain 3 gamma,GO:0031090//organelle membrane;GO:0012505//endomembrane system;GO:0005874//microtubule;GO:0031410//cytoplasmic vesicle;GO:0005776//autophagic vacuole;GO:0000421//autophagic vacuole membrane,GO:0006914//autophagy,GO:0005515//protein binding,-
440757,0,0,0,0,0,0,0,0,9,0,0,0,LINC00851;long intergenic non-protein coding RNA 851,-,-,-,-
440822,0,0,0,0,0,0,29,0,37,0,0,0,PIWIL3;piwi-like RNA-mediated gene silencing 3,GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006417//regulation of translation;GO:0031047//gene silencing by RNA;GO:0007126//meiotic nuclear division;GO:0030154//cell differentiation,GO:0003723//RNA binding,K02156//Dorso-ventral axis formation
440829,118,0,0,0,0,18,0,0,0,0,0,195,SHISA8;shisa family member 8,GO:0016021//integral component of membrane,-,-,-
440836,0,0,0,0,6,0,0,7,0,14,0,0,ODF3B;outer dense fiber of sperm tails 3B,-,-,-,-
440854,91,0,0,0,0,19,0,0,36,0,0,72,CAPN14;calpain 14,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
440888,0,0,0,0,0,10,0,0,25,0,0,1,ACTR3BP2;ACTR3B pseudogene 2,-,-,-,K05692//Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection;Gastric acid secretion;Pathogenic Escherichia coli infection;Vibrio cholerae infection;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
440910,0,0,0,0,0,0,0,1,13,0,0,0,LOC440910;uncharacterized LOC440910,-,-,-,-
440915,92,0,0,0,0,0,0,0,4,0,0,1,"POTEKP;POTE ankyrin domain family, member K, pseudogene",GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton,GO:0002576//platelet degranulation;GO:0030168//platelet activation;GO:0007596//blood coagulation,GO:0005524//ATP binding,K08803//Pathways in cancer;Bladder cancer
440955,0,0,0,0,0,0,18,0,0,0,0,0,TMEM89;transmembrane protein 89,GO:0005634//nucleus;GO:0016021//integral component of membrane,-,-,-
440957,0,0,0,5,1,0,0,0,0,0,0,0,SMIM4;small integral membrane protein 4,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,-
440970,0,0,0,0,0,34,42,0,10,0,22,0,LINC00971;long intergenic non-protein coding RNA 971,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer
440993,0,0,0,0,0,0,0,11,0,0,0,0,LINC00969;long intergenic non-protein coding RNA 969,-,-,-,-
441024,0,0,0,19,0,0,0,56,0,0,13,0,MTHFD2L;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0035999//tetrahydrofolate interconversion;GO:0000105//histidine biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0006164//purine nucleotide biosynthetic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006730//one-carbon metabolic process,GO:0004477//methenyltetrahydrofolate cyclohydrolase activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0004487//methylenetetrahydrofolate dehydrogenase (NAD+) activity;GO:0004329//formate-tetrahydrofolate ligase activity,K13403//Metabolic pathways;One carbon pool by folate
441027,0,0,0,0,0,23,0,0,7,0,0,0,TMEM150C;transmembrane protein 150C,GO:0016021//integral component of membrane,-,-,-
441046,0,0,0,0,0,0,5,0,2,0,0,0,"GUSBP5;glucuronidase, beta pseudogene 5",-,-,-,K01195//Drug metabolism - other enzymes;Lysosome;Starch and sucrose metabolism;Glycosaminoglycan degradation;Pentose and glucuronate interconversions;Metabolic pathways;Porphyrin and chlorophyll metabolism
441054,0,0,0,0,0,0,9,0,66,0,0,0,C4orf47;chromosome 4 open reading frame 47,-,-,-,-
441058,11,0,0,0,0,1,0,2,21,1,0,1,MGC39584;uncharacterized LOC441058,-,-,-,-
441061,0,0,0,0,0,0,0,28,0,0,0,0,MARCH11;membrane-associated ring finger (C3HC4) 11,GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
441081,19,0,0,0,0,16,0,0,0,0,0,0,LOC441081;POM121 membrane glycoprotein (rat) pseudogene,GO:0016021//integral component of membrane,-,-,K14316//RNA transport
441089,0,0,0,0,0,0,0,0,16,0,0,213,CRSP8P;mediator complex subunit 27 pseudogene,-,-,-,-
441094,0,0,16,0,0,0,0,141,25,0,11,0,NR2F1-AS1;NR2F1 antisense RNA 1,-,-,-,K09057//Circadian rhythm - fly;K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
441150,0,0,0,0,1,0,0,0,0,0,0,0,C6orf226;chromosome 6 open reading frame 226,-,-,-,-
441151,0,0,0,0,8,8,12,0,31,7,0,187,TMEM151B;transmembrane protein 151B,GO:0016021//integral component of membrane,-,-,-
441155,0,1,0,0,1,14,36,0,43,0,0,0,LOC441155;zinc finger CCCH-type domain-containing-like,-,-,-,K04157//Serotonergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction;Gap junction
441161,0,0,0,0,0,0,0,0,11,0,0,0,OOEP;oocyte expressed protein,GO:0005938//cell cortex;GO:0045177//apical part of cell;GO:0043234//protein complex,GO:0043623//cellular protein complex assembly;GO:0001701//in utero embryonic development;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0007566//embryo implantation;GO:0006468//protein phosphorylation;GO:0009880//embryonic pattern specification;GO:0009566//fertilization,GO:0003723//RNA binding,-
441168,47,0,0,0,0,0,5,0,5,0,0,0,"FAM26F;family with sequence similarity 26, member F",GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
441177,0,0,0,0,0,0,23,0,12,0,0,0,LINC00602;long intergenic non-protein coding RNA 602,-,-,-,-
441194,0,0,0,0,0,0,0,0,16,0,13,0,PMS2CL;PMS2 C-terminal like pseudogene,-,-,-,K10858//Fanconi anemia pathway;Mismatch repair
441208,0,19,0,0,0,0,5,36,9,0,12,0,ZNRF2P1;zinc and ring finger 2 pseudogene 1,-,-,-,-
441234,0,0,0,0,0,16,0,0,45,0,0,0,ZNF716;zinc finger protein 716,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
441242,0,34,2,0,0,0,12,216,58,0,0,0,LOC441242;uncharacterized LOC441242,-,-,-,-
441250,0,0,0,0,11,24,0,0,49,0,0,0,TYW1B;tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae),-,GO:0055114//oxidation-reduction process;GO:0008033//tRNA processing,"GO:0010181//FMN binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005506//iron ion binding;GO:0016829//lyase activity;GO:0016491//oxidoreductase activity",-
441251,0,0,0,0,9,7,29,0,0,0,13,0,"SPDYE7P;speedy/RINGO cell cycle regulator family member E7, pseudogene",-,-,-,K08694//Progesterone-mediated oocyte maturation;Oocyte meiosis
441263,0,0,0,0,0,0,0,0,0,0,0,554,DTX2P1-UPK3BP1-PMS2P11;DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene,-,-,-,K06058//Notch signaling pathway
441272,1,54,0,85,252,15,0,98,12,0,358,0,SPDYE3;speedy/RINGO cell cycle regulator family member E3,-,-,-,K08694//Progesterone-mediated oocyte maturation;Oocyte meiosis
441282,0,0,0,0,0,19,17,0,32,0,14,0,"AKR1B15;aldo-keto reductase family 1, member B15",-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K00011//Fructose and mannose metabolism;Glycerolipid metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Galactose metabolism;Pyruvate metabolism
441294,4,0,3,10,3,0,0,1,1,1,7,0,"CTAGE15;CTAGE family, member 15",GO:0016021//integral component of membrane,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton
441317,2,0,0,0,0,0,2,0,1,0,0,123,FAM90A7P;putative protein FAM90A7,-,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,-
441369,0,0,0,0,0,17,36,0,35,0,0,0,FLJ46284;uncharacterized LOC441369,-,-,-,-
441376,0,0,0,0,0,0,9,0,17,0,0,0,AARD;alanine and arginine rich domain containing protein,-,GO:0030324//lung development,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
441381,0,88,61,96,71,0,40,322,31,0,218,0,LRRC24;leucine rich repeat containing 24,GO:0016021//integral component of membrane,-,-,K06838//Axon guidance
441389,0,0,0,0,0,6,39,0,16,0,0,0,LINC01239;long intergenic non-protein coding RNA 1239,-,-,-,K11433//Lysine degradation
441425,0,0,0,0,0,0,0,0,2,0,0,0,"ANKRD20A3;ankyrin repeat domain 20 family, member A3",-,-,-,-
441452,0,0,28,0,0,0,3,0,26,0,0,0,"SPATA31C1;SPATA31 subfamily C, member 1",GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
441454,0,0,0,0,0,0,0,0,13,0,0,0,"LOC441454;prothymosin, alpha pseudogene",-,-,-,-
441455,0,0,0,0,0,0,42,10,0,0,0,0,LOC441455;makorin ring finger protein 1 pseudogene,-,-,-,-
441457,0,0,0,9,0,0,1,37,36,0,0,0,NUTM2G;NUT family member 2G,-,-,-,K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
441459,36,0,0,0,16,32,27,0,21,0,0,0,ANKRD18B;ankyrin repeat domain 18B,-,-,-,-
441476,0,0,0,0,0,0,0,0,8,0,0,0,C9orf173;chromosome 9 open reading frame 173,-,-,-,-
441478,0,0,0,6,17,0,39,0,0,0,26,0,NRARP;NOTCH-regulated ankyrin repeat protein,-,GO:1902367//negative regulation of Notch signaling pathway involved in somitogenesis;GO:0045581//negative regulation of T cell differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0001938//positive regulation of endothelial cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045746//negative regulation of Notch signaling pathway;GO:0032525//somite rostral/caudal axis specification;GO:0001569//patterning of blood vessels;GO:0022407//regulation of cell-cell adhesion,-,K06270//Focal adhesion;Long-term potentiation;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;K12329//Vascular smooth muscle contraction
441490,0,0,0,0,0,0,9,0,0,0,0,0,"FTH1P18;ferritin, heavy polypeptide 1 pseudogene 18",-,-,-,K00522//Porphyrin and chlorophyll metabolism;Mineral absorption
441509,0,14,65,11,0,17,0,0,24,0,17,662,"GLRA4;glycine receptor, alpha 4",GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex,GO:1902476//chloride transmembrane transport,GO:0005230//extracellular ligand-gated ion channel activity;GO:0005254//chloride channel activity;GO:0016594//glycine binding;GO:0022824//transmitter-gated ion channel activity,-
441518,0,15,0,45,168,0,0,349,0,1,102,0,"FAM127C;family with sequence similarity 127, member C",-,-,-,-
441549,0,0,0,0,0,18,0,0,20,0,0,0,CDNF;cerebral dopamine neurotrophic factor,GO:0005576//extracellular region,-,GO:0008083//growth factor activity,-
441581,0,0,0,0,0,0,41,0,0,0,0,0,"FRG2B;FSHD region gene 2 family, member B",GO:0005634//nucleus,-,-,-
441608,0,0,0,0,0,0,0,0,0,118,0,0,"OR5B3;olfactory receptor, family 5, subfamily B, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
441631,0,0,0,0,0,0,15,0,86,0,18,0,TSPAN11;tetraspanin 11,GO:0016021//integral component of membrane,-,-,-
441639,0,0,0,0,0,0,0,0,1,0,0,0,"OR9K2;olfactory receptor, family 9, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
441666,61,0,0,0,0,0,23,1,54,0,0,0,LOC441666;zinc finger protein 91 pseudogene,-,-,-,-
441669,0,0,0,0,0,0,0,0,32,0,0,0,"OR4Q3;olfactory receptor, family 4, subfamily Q, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
441670,0,0,0,0,0,0,0,0,15,0,0,0,"OR4M1;olfactory receptor, family 4, subfamily M, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
441687,0,0,0,0,0,17,0,0,0,0,0,0,"TEX21P;testis expressed 21, pseudogene",-,-,-,-
441733,0,20,0,6,0,17,21,0,0,0,14,0,"PRKXP1;protein kinase, X-linked, pseudogene 1",-,-,-,K04345//Hedgehog signaling pathway;Apoptosis;MAPK signaling pathway;Oocyte meiosis;Morphine addiction;Epstein-Barr virus infection;GnRH signaling pathway;Chemokine signaling pathway;Cocaine addiction;Gap junction;Dopaminergic synapse;Meiosis - yeast;Alcoholism;Serotonergic synapse;Prion diseases;Gastric acid secretion;Bile secretion;HTLV-I infection;Retrograde endocannabinoid signaling;Olfactory transduction;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Amphetamine addiction;Glutamatergic synapse;Taste transduction;Vascular smooth muscle contraction;Vasopressin-regulated water reabsorption;Wnt signaling pathway;Amoebiasis;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Long-term potentiation;Melanogenesis;Vibrio cholerae infection;GABAergic synapse;Cholinergic synapse;Dilated cardiomyopathy;Salivary secretion
441818,74,0,0,0,0,1,0,0,43,0,16,0,WBP11P1;WW domain binding protein 11 pseudogene 1,-,-,-,K12866//Spliceosome
441864,0,0,0,0,0,0,0,43,14,0,0,0,"TARM1;T cell-interacting, activating receptor on myeloid cells 1",GO:0016021//integral component of membrane,-,-,K14377//Osteoclast differentiation
441869,0,0,0,0,0,0,0,0,9,0,0,0,ANKRD65;ankyrin repeat domain 65,-,-,-,-
441897,0,0,0,0,0,0,0,0,9,0,0,0,PGCP1;progastricsin (pepsinogen C) pseudogene 1,-,-,-,-
441911,0,0,0,0,0,0,0,65,0,0,0,0,"OR10J3;olfactory receptor, family 10, subfamily J, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
441925,0,0,0,0,0,0,1,0,11,0,0,0,"BECN1P1;beclin 1, autophagy related, pseudogene 1",GO:0005737//cytoplasm,GO:1990172//G-protein coupled receptor catabolic process;GO:0006914//autophagy;GO:0008333//endosome to lysosome transport,GO:0005515//protein binding,K08334//Regulation of autophagy
441932,0,0,0,0,0,0,0,0,10,0,0,0,"OR2W5;olfactory receptor, family 2, subfamily W, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
441933,0,0,0,0,0,0,0,0,21,0,0,0,"OR13G1;olfactory receptor, family 13, subfamily G, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
441951,0,0,0,27,87,0,0,0,0,0,6,191,ZFAS1;ZNFX1 antisense RNA 1,-,-,-,-
442038,0,0,0,0,9,0,0,0,0,0,0,0,"SULT1C3;sulfotransferase family, cytosolic, 1C, member 3",GO:0005737//cytoplasm,GO:0006790//sulfur compound metabolic process,GO:0004062//aryl sulfotransferase activity;GO:0004027//alcohol sulfotransferase activity,-
442075,0,16,0,29,27,0,0,53,61,0,26,0,EMC3-AS1;EMC3 antisense RNA 1,-,-,-,-
442117,0,1,28,0,0,0,10,0,19,0,0,0,GALNTL6;polypeptide N-acetylgalactosaminyltransferase-like 6,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation,GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
442132,0,42,0,5,0,9,13,0,45,0,0,0,LOC442132;golgin A6 family-like 1 pseudogene,-,-,-,-
442211,0,0,0,0,0,0,0,0,0,0,1,0,"ATP6V0CP3;ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c pseudogene 3",-,-,-,K02155//Vibrio cholerae infection;Lysosome;Epithelial cell signaling in Helicobacter pylori infection;Metabolic pathways;Oxidative phosphorylation;Synaptic vesicle cycle;Tuberculosis;Phagosome;Collecting duct acid secretion;Rheumatoid arthritis
442213,76,0,0,0,0,0,0,0,15,0,2,0,PTCHD4;patched domain containing 4,GO:0016021//integral component of membrane,GO:0007165//signal transduction,GO:0008158//hedgehog receptor activity,K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K06225//Basal cell carcinoma;Hedgehog signaling pathway;Pathways in cancer;K12385//Lysosome;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
442245,0,0,0,0,0,0,0,0,49,0,0,0,GSTM2P1;glutathione S-transferase mu 2 (muscle) pseudogene 1,-,-,-,K00799//Metabolism of xenobiotics by cytochrome P450;Prostate cancer;Glutathione metabolism;Drug metabolism - cytochrome P450;Pathways in cancer
442319,0,0,0,0,13,0,0,0,39,0,0,0,"ZNF727P;zinc finger protein 727, pseudogene",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
442361,0,0,0,0,0,0,0,0,10,0,0,0,"OR2A2;olfactory receptor, family 2, subfamily A, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
442421,58,0,0,0,0,27,17,1,40,132,22,0,PTGER4P2-CDK2AP2P2;PTGER4P2-CDK2AP2P2 readthrough transcribed pseudogene,-,-,-,K04261//Neuroactive ligand-receptor interaction
442425,0,0,0,0,0,0,0,0,17,0,0,0,FOXB2;forkhead box B2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
442444,0,0,0,0,0,15,5,0,0,0,0,0,"FAM47C;family with sequence similarity 47, member C",-,-,-,K09187//Lysine degradation
442459,82,0,0,0,0,6,0,38,44,1,0,0,XRCC6P5;X-ray repair complementing defective repair in Chinese hamster cells 6 pseudogene 5,-,-,-,K10884//Non-homologous end-joining
442523,0,0,0,0,0,0,0,0,10,0,0,0,DPY19L2P4;DPY19L2 pseudogene 4,-,-,-,-
442524,0,0,74,0,12,0,0,85,2,0,18,0,DPY19L2P3;DPY19L2 pseudogene 3,-,-,-,-
442582,24,36,1,1,0,0,21,0,15,0,0,0,STAG3L2;stromal antigen 3-like 2 (pseudogene),GO:0005634//nucleus,-,-,K13055//Oocyte meiosis
442720,0,0,0,0,0,13,1,0,28,0,0,0,"EIF3IP1;eukaryotic translation initiation factor 3, subunit I pseudogene 1",-,-,-,K03246//RNA transport
442721,0,0,0,0,0,18,0,0,0,0,0,0,LMOD2;leiomodin 2 (cardiac),GO:0005856//cytoskeleton,-,GO:0003779//actin binding;GO:0005523//tropomyosin binding,-
442898,0,0,0,0,0,0,0,0,17,0,0,0,MIR324;microRNA 324,-,-,-,-
442900,0,0,0,0,0,0,0,0,12,0,0,0,MIR326;microRNA 326,-,-,-,-
442901,6,0,0,0,0,0,0,0,0,0,0,0,MIR328;microRNA 328,-,-,-,-
442909,0,0,0,0,0,0,0,0,14,0,0,0,MIR342;microRNA 342,-,-,-,-
442918,0,0,0,0,0,0,0,0,8,0,0,0,MIR373;microRNA 373,-,-,-,-
443,0,0,0,0,0,0,0,0,35,0,0,0,ASPA;aspartoacylase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0006533//aspartate catabolic process;GO:0022010//central nervous system myelination,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0004046//aminoacylase activity;GO:0046872//metal ion binding;GO:0019807//aspartoacylase activity","K01437//Histidine metabolism;Alanine, aspartate and glutamate metabolism"
4430,0,0,0,12,92,22,0,0,32,0,7,0,MYO1B;myosin IB,GO:0010008//endosome membrane;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0016459//myosin complex;GO:0005737//cytoplasm;GO:0032588//trans-Golgi network membrane;GO:0005903//brush border;GO:0005884//actin filament;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery,GO:0030048//actin filament-based movement;GO:0006892//post-Golgi vesicle-mediated transport;GO:0008152//metabolic process;GO:0007015//actin filament organization;GO:0051017//actin filament bundle assembly,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0000146//microfilament motor activity;GO:0051015//actin filament binding",-
4435,0,0,0,0,0,16,0,45,10,0,0,0,"CITED1;Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1",GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043524//negative regulation of neuron apoptotic process;GO:0006913//nucleocytoplasmic transport;GO:0030318//melanocyte differentiation;GO:0070741//response to interleukin-6;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0034341//response to interferon-gamma;GO:0070670//response to interleukin-4;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0071104//response to interleukin-9;GO:0070669//response to interleukin-2;GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0007420//brain development;GO:0010628//positive regulation of gene expression;GO:0001890//placenta development;GO:0070555//response to interleukin-1;GO:0000578//embryonic axis specification;GO:0071107//response to parathyroid hormone;GO:0051591//response to cAMP;GO:0030178//negative regulation of Wnt signaling pathway;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060711//labyrinthine layer development;GO:0071559//response to transforming growth factor beta;GO:0060712//spongiotrophoblast layer development;GO:0043627//response to estrogen;GO:0042438//melanin biosynthetic process;GO:0071105//response to interleukin-11;GO:0060395//SMAD protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001570//vasculogenesis;GO:0001656//metanephros development;GO:0043473//pigmentation;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0032868//response to insulin;GO:0032496//response to lipopolysaccharide;GO:0060231//mesenchymal to epithelial transition",GO:0003682//chromatin binding;GO:0050693//LBD domain binding;GO:0003713//transcription coactivator activity;GO:0008022//protein C-terminus binding;GO:0044212//transcription regulatory region DNA binding;GO:0070410//co-SMAD binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity,-
4436,0,0,1,0,46,20,44,0,15,0,0,0,MSH2;mutS homolog 2,GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0032301//MutSalpha complex;GO:0032302//MutSbeta complex,GO:0006311//meiotic gene conversion;GO:0006281//DNA repair;GO:0007050//cell cycle arrest;GO:0006200//ATP catabolic process;GO:0006302//double-strand break repair;GO:0043524//negative regulation of neuron apoptotic process;GO:0030183//B cell differentiation;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0045910//negative regulation of DNA recombination;GO:0045128//negative regulation of reciprocal meiotic recombination;GO:0006298//mismatch repair;GO:0008584//male gonad development;GO:0008340//determination of adult lifespan;GO:0051096//positive regulation of helicase activity;GO:0019724//B cell mediated immunity;GO:0010165//response to X-ray;GO:0043570//maintenance of DNA repeat elements;GO:0006301//postreplication repair;GO:0006119//oxidative phosphorylation;GO:0000710//meiotic mismatch repair;GO:0045190//isotype switching;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0031573//intra-S DNA damage checkpoint;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0001701//in utero embryonic development;GO:0007281//germ cell development;GO:0010224//response to UV-B,GO:0032181//dinucleotide repeat insertion binding;GO:0000404//heteroduplex DNA loop binding;GO:0032137//guanine/thymine mispair binding;GO:0032143//single thymine insertion binding;GO:0016887//ATPase activity;GO:0003697//single-stranded DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0003690//double-stranded DNA binding;GO:0000287//magnesium ion binding;GO:0032405//MutLalpha complex binding;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0030983//mismatched DNA binding;GO:0032357//oxidized purine DNA binding;GO:0032142//single guanine insertion binding;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0000400//four-way junction DNA binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0008022//protein C-terminus binding;GO:0043531//ADP binding;GO:0019237//centromeric DNA binding;GO:0000406//double-strand/single-strand DNA junction binding;GO:0000403//Y-form DNA binding;GO:0005515//protein binding,K08735//Colorectal cancer;Mismatch repair;Pathways in cancer
4437,0,45,0,24,63,10,0,450,45,1,64,0,MSH3;mutS homolog 3,GO:0016020//membrane;GO:0000228//nuclear chromosome;GO:0005634//nucleus;GO:0032302//MutSbeta complex,GO:0000710//meiotic mismatch repair;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0045910//negative regulation of DNA recombination;GO:0006298//mismatch repair;GO:0007131//reciprocal meiotic recombination;GO:0051096//positive regulation of helicase activity;GO:0043570//maintenance of DNA repeat elements,GO:0005515//protein binding;GO:0032139//dinucleotide insertion or deletion binding;GO:0000403//Y-form DNA binding;GO:0000406//double-strand/single-strand DNA junction binding;GO:0019237//centromeric DNA binding;GO:0032142//single guanine insertion binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0032357//oxidized purine DNA binding;GO:0030983//mismatched DNA binding;GO:0042803//protein homodimerization activity;GO:0008094//DNA-dependent ATPase activity;GO:0003697//single-stranded DNA binding;GO:0000404//heteroduplex DNA loop binding;GO:0032137//guanine/thymine mispair binding;GO:0032181//dinucleotide repeat insertion binding,K08736//Pathways in cancer;Colorectal cancer;Mismatch repair
4438,0,0,0,0,0,19,12,0,89,0,0,0,MSH4;mutS homolog 4,GO:0032300//mismatch repair complex;GO:0005634//nucleus;GO:0000795//synaptonemal complex,GO:0001541//ovarian follicle development;GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0045143//homologous chromosome segregation;GO:0007292//female gamete generation;GO:0000710//meiotic mismatch repair;GO:0051026//chiasma assembly;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0003684//damaged DNA binding;GO:0030983//mismatched DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
444,134,0,17,0,0,43,42,100,33,59,0,0,ASPH;aspartate beta-hydroxylase,GO:0034704//calcium channel complex;GO:0032541//cortical endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0033018//sarcoplasmic reticulum lumen,"GO:1901879//regulation of protein depolymerization;GO:0060021//palate development;GO:0010649//regulation of cell communication by electrical coupling;GO:0031647//regulation of protein stability;GO:0008285//negative regulation of cell proliferation;GO:0060325//face morphogenesis;GO:0007389//pattern specification process;GO:0032237//activation of store-operated calcium channel activity;GO:0071277//cellular response to calcium ion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0033198//response to ATP;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0090316//positive regulation of intracellular protein transport;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0045862//positive regulation of proteolysis;GO:0055114//oxidation-reduction process;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0035108//limb morphogenesis;GO:0070588//calcium ion transmembrane transport;GO:0031585//regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0006936//muscle contraction;GO:0042264//peptidyl-aspartic acid hydroxylation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0005513//detection of calcium ion",GO:0005509//calcium ion binding;GO:0009055//electron carrier activity;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0044325//ion channel binding;GO:0008307//structural constituent of muscle;GO:0004597//peptide-aspartate beta-dioxygenase activity,-
4440,98,14,0,1,0,0,0,0,19,0,19,0,MSI1;musashi RNA-binding protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005844//polysome,GO:0009725//response to hormone;GO:0007399//nervous system development;GO:0030855//epithelial cell differentiation,GO:0003723//RNA binding;GO:0008266//poly(U) RNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K14411//mRNA surveillance pathway
445,0,0,0,0,13,0,0,0,22,0,0,303,ASS1;argininosuccinate synthase 1,GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0005764//lysosome;GO:0005634//nucleus;GO:0070852//cell body fiber;GO:0005829//cytosol;GO:0043204//perikaryon,GO:0071400//cellular response to oleic acid;GO:0001889//liver development;GO:0007494//midgut development;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0001822//kidney development;GO:0006526//arginine biosynthetic process;GO:0000053//argininosuccinate metabolic process;GO:0010043//response to zinc ion;GO:0007568//aging;GO:0071499//cellular response to laminar fluid shear stress;GO:0032355//response to estradiol;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0071549//cellular response to dexamethasone stimulus;GO:0071320//cellular response to cAMP;GO:0034641//cellular nitrogen compound metabolic process;GO:0000050//urea cycle;GO:0071377//cellular response to glucagon stimulus;GO:0071230//cellular response to amino acid stimulus;GO:0071242//cellular response to ammonium ion;GO:1903038//negative regulation of leukocyte cell-cell adhesion;GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0060416//response to growth hormone;GO:0006953//acute-phase response;GO:0071418//cellular response to amine stimulus;GO:0010046//response to mycotoxin;GO:0060539//diaphragm development;GO:0000052//citrulline metabolic process;GO:0006531//aspartate metabolic process;GO:0071346//cellular response to interferon-gamma;GO:0007584//response to nutrient,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0015643//toxic substance binding;GO:0016597//amino acid binding;GO:0004055//argininosuccinate synthase activity;GO:0005524//ATP binding,"K01940//Biosynthesis of secondary metabolites;Arginine and proline metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
445328,0,1,0,0,2,0,0,0,2,0,0,0,ARHGEF35;Rho guanine nucleotide exchange factor (GEF) 35,-,-,-,-
445347,0,77,2,87,135,10,0,0,9,113,0,0,TARP;TCR gamma alternate reading frame protein,-,-,-,K06554//Primary immunodeficiency;K10785//HTLV-I infection;Chagas disease (American trypanosomiasis);Malaria;Type I diabetes mellitus;Transcriptional misregulation in cancer;Calcium signaling pathway;Cell adhesion molecules (CAMs);Graft-versus-host disease;Asthma;Measles;Antigen processing and presentation;NF-kappa B signaling pathway;Rheumatoid arthritis;Autoimmune thyroid disease;Intestinal immune network for IgA production;Staphylococcus aureus infection;Allograft rejection;T cell receptor signaling pathway;Viral myocarditis;Systemic lupus erythematosus
445571,0,0,0,0,0,10,0,0,14,0,0,0,CBWD3;COBW domain containing 3,-,-,GO:0005524//ATP binding,-
445577,0,35,71,83,93,0,5,191,40,0,100,0,C9orf129;chromosome 9 open reading frame 129,-,-,-,-
445582,4,0,8,0,32,0,2,63,0,0,13,0,"POTEE;POTE ankyrin domain family, member E",GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0021762//substantia nigra development;GO:0001895//retina homeostasis,-,K05692//Pathogenic Escherichia coli infection;Gastric acid secretion;Vibrio cholerae infection;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection
445815,0,0,0,0,0,0,0,0,12,0,0,0,PALM2-AKAP2;PALM2-AKAP2 readthrough,-,-,-,-
4477,0,17,0,0,7,0,0,0,0,0,0,0,"MSMB;microseminoprotein, beta-",GO:0005634//nucleus;GO:0005615//extracellular space,-,-,-
4478,0,0,0,10,9,35,1,1,63,0,11,0,MSN;moesin,GO:0001931//uropod;GO:0031528//microvillus membrane;GO:0031982//vesicle;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005902//microvillus;GO:0005856//cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0030175//filopodium;GO:0072562//blood microparticle,GO:0050900//leukocyte migration;GO:0007159//leukocyte cell-cell adhesion;GO:0010628//positive regulation of gene expression;GO:2000401//regulation of lymphocyte migration;GO:0006928//cellular component movement;GO:0061028//establishment of endothelial barrier;GO:0022614//membrane to membrane docking,GO:0050839//cell adhesion molecule binding;GO:0003725//double-stranded RNA binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005102//receptor binding,K05763//Regulation of actin cytoskeleton;Measles;Leukocyte transendothelial migration
4481,0,0,0,0,0,16,0,0,44,0,1,0,MSR1;macrophage scavenger receptor 1,GO:0005829//cytosol;GO:0034362//low-density lipoprotein particle;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005581//collagen trimer,GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0010886//positive regulation of cholesterol storage;GO:0034381//plasma lipoprotein particle clearance;GO:0006898//receptor-mediated endocytosis;GO:0030301//cholesterol transport;GO:0042953//lipoprotein transport,GO:0005044//scavenger receptor activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding,K06558//Phagosome
4482,147,0,0,0,19,0,0,0,12,1,0,361,MSRA;methionine sulfoxide reductase A,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0055114//oxidation-reduction process;GO:0030091//protein repair;GO:0006464//cellular protein modification process;GO:0006555//methionine metabolic process;GO:0006979//response to oxidative stress,GO:0008113//peptide-methionine (S)-S-oxide reductase activity,-
4485,0,0,0,9,0,40,0,0,8,85,3,0,MST1;macrophage stimulating 1 (hepatocyte growth factor-like),GO:0070062//extracellular vesicular exosome,GO:0007566//embryo implantation;GO:0006508//proteolysis;GO:0030317//sperm motility;GO:0007283//spermatogenesis,GO:0004252//serine-type endopeptidase activity,K05460//Pathways in cancer;Malaria;Melanoma;Cytokine-cytokine receptor interaction;Renal cell carcinoma;Focal adhesion
4486,44,0,46,11,0,13,0,143,30,0,26,0,MST1R;macrophage stimulating 1 receptor (c-met-related tyrosine kinase),GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0001725//stress fiber,GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006928//cellular component movement;GO:0009615//response to virus;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007275//multicellular organismal development;GO:0045087//innate immune response;GO:0051897//positive regulation of protein kinase B signaling;GO:0006952//defense response;GO:0008284//positive regulation of cell proliferation;GO:0038145//macrophage colony-stimulating factor signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0007165//signal transduction;GO:0007338//single fertilization,GO:0005524//ATP binding;GO:0005011//macrophage colony-stimulating factor receptor activity;GO:0019899//enzyme binding;GO:0005515//protein binding,-
4488,0,0,0,0,25,14,0,0,2,144,0,0,MSX2;msh homeobox 2,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0003148//outflow tract septum morphogenesis;GO:0060364//frontal suture morphogenesis;GO:0051795//positive regulation of catagen;GO:0035313//wound healing, spreading of epidermal cells;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071363//cellular response to growth factor stimulus;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0071392//cellular response to estradiol stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023019//signal transduction involved in regulation of gene expression;GO:0045599//negative regulation of fat cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0001649//osteoblast differentiation;GO:0032792//negative regulation of CREB transcription factor activity;GO:0045617//negative regulation of keratinocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0090427//activation of meiosis;GO:0060346//bone trabecula formation;GO:0002076//osteoblast development;GO:0002063//chondrocyte development;GO:0003416//endochondral bone growth;GO:0070166//enamel mineralization;GO:0035116//embryonic hindlimb morphogenesis;GO:2001055//positive regulation of mesenchymal cell apoptotic process;GO:0061312//BMP signaling pathway involved in heart development;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0060363//cranial suture morphogenesis;GO:0042640//anagen;GO:0035880//embryonic nail plate morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0008134//transcription factor binding,K09341//HTLV-I infection
448831,4,0,0,0,0,0,0,0,0,0,0,0,FRG2;FSHD region gene 2,GO:0005634//nucleus,-,-,K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation
448834,0,0,0,0,0,0,0,0,17,0,0,0,KPRP;keratinocyte proline-rich protein,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,-,-
4489,0,0,0,0,0,0,0,0,0,52,11,82,MT1A;metallothionein 1A,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0071276//cellular response to cadmium ion;GO:0071294//cellular response to zinc ion;GO:0045926//negative regulation of growth,GO:0005515//protein binding;GO:0008270//zinc ion binding,-
4490,65,0,0,0,0,0,0,0,0,0,0,0,MT1B;metallothionein 1B,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0071294//cellular response to zinc ion;GO:0045926//negative regulation of growth,GO:0008270//zinc ion binding,K14739//Mineral absorption
4493,65,0,0,0,2,0,0,0,0,0,0,0,MT1E;metallothionein 1E,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045926//negative regulation of growth;GO:0071294//cellular response to zinc ion;GO:0071276//cellular response to cadmium ion,GO:0008270//zinc ion binding,K14739//Mineral absorption
449520,0,0,0,0,0,15,0,0,0,0,0,0,GGNBP1;gametogenetin binding protein 1 (pseudogene),GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0030154//cell differentiation;GO:0000266//mitochondrial fission;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,-
4496,26,0,2,0,0,0,0,0,0,0,0,0,MT1H;metallothionein 1H,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0045926//negative regulation of growth;GO:0071294//cellular response to zinc ion;GO:0071276//cellular response to cadmium ion,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
4498,0,0,0,0,0,34,39,0,0,0,0,0,"MT1JP;metallothionein 1J, pseudogene",-,-,-,K14739//Mineral absorption
4499,0,0,0,0,0,0,0,0,0,0,0,1,MT1M;metallothionein 1M,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0071294//cellular response to zinc ion;GO:0045926//negative regulation of growth,GO:0008270//zinc ion binding,K14739//Mineral absorption
4500,0,0,0,0,0,25,0,0,10,0,0,0,MT1L;metallothionein 1L (gene/pseudogene),-,-,-,-
4501,0,0,0,0,3,0,22,0,0,0,0,0,MT1X;metallothionein 1X,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0010038//response to metal ion;GO:0071294//cellular response to zinc ion;GO:0045926//negative regulation of growth;GO:0036018//cellular response to erythropoietin;GO:0071276//cellular response to cadmium ion,GO:0008270//zinc ion binding;GO:0046872//metal ion binding,K14739//Mineral absorption
4507,0,1,1,36,59,30,22,0,17,0,0,0,MTAP;methylthioadenosine phosphorylase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006139//nucleobase-containing compound metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0006738//nicotinamide riboside catabolic process;GO:0006166//purine ribonucleoside salvage;GO:0006595//polyamine metabolic process;GO:0044281//small molecule metabolic process,GO:0017061//S-methyl-5-thioadenosine phosphorylase activity;GO:0004645//phosphorylase activity,K00772//Metabolic pathways;Cysteine and methionine metabolism
4515,1,0,0,0,6,0,0,0,2,0,0,0,MTCP1;mature T-cell proliferation 1,GO:0005739//mitochondrion,GO:0008283//cell proliferation,-,-
4520,36,0,0,6,38,20,0,0,24,0,0,0,MTF1;metal-regulatory transcription factor 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046686//response to cadmium ion;GO:0006351//transcription, DNA-templated;GO:0006979//response to oxidative stress;GO:0010038//response to metal ion;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001047//core promoter binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0035035//histone acetyltransferase binding,-
4521,0,0,0,7,0,0,2,0,0,0,0,0,NUDT1;nudix (nucleoside diphosphate linked moiety X)-type motif 1,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0034656//nucleobase-containing small molecule catabolic process;GO:0006979//response to oxidative stress;GO:0006184//GTP catabolic process;GO:0006195//purine nucleotide catabolic process;GO:0006203//dGTP catabolic process;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0042262//DNA protection;GO:0046061//dATP catabolic process,"GO:0046872//metal ion binding;GO:0035539//8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity;GO:0030515//snoRNA binding;GO:0047693//ATP diphosphatase activity;GO:0003924//GTPase activity;GO:0050072//m7G(5')pppN diphosphatase activity;GO:0008413//8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity",-
4522,0,0,1,80,225,4,0,0,37,8,55,0,"MTHFD1;methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0009396//folic acid-containing compound biosynthetic process;GO:0006730//one-carbon metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0009086//methionine biosynthetic process;GO:0046655//folic acid metabolic process;GO:0035999//tetrahydrofolate interconversion;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0000105//histidine biosynthetic process,GO:0005524//ATP binding;GO:0004329//formate-tetrahydrofolate ligase activity;GO:0004486//methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity;GO:0004488//methylenetetrahydrofolate dehydrogenase (NADP+) activity;GO:0004477//methenyltetrahydrofolate cyclohydrolase activity,K00288//One carbon pool by folate;Metabolic pathways
4524,1,41,99,25,20,0,110,445,70,0,38,0,MTHFR;methylenetetrahydrofolate reductase (NAD(P)H),GO:0043005//neuron projection;GO:0005829//cytosol,GO:0046655//folic acid metabolic process;GO:0009086//methionine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0042493//response to drug;GO:0033274//response to vitamin B2;GO:0046500//S-adenosylmethionine metabolic process;GO:0050667//homocysteine metabolic process;GO:0008015//blood circulation;GO:0035999//tetrahydrofolate interconversion;GO:0051593//response to folic acid;GO:0070555//response to interleukin-1;GO:0006520//cellular amino acid metabolic process;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0001666//response to hypoxia,GO:0004489//methylenetetrahydrofolate reductase (NAD(P)H) activity;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0072341//modified amino acid binding,K00297//Metabolic pathways;One carbon pool by folate;Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism
4528,6,18,1,14,59,17,0,0,129,0,5,0,MTIF2;mitochondrial translational initiation factor 2,GO:0005739//mitochondrion,GO:0001732//formation of cytoplasmic translation initiation complex;GO:0032790//ribosome disassembly;GO:0006184//GTP catabolic process;GO:0006446//regulation of translational initiation,"GO:0008135//translation factor activity, nucleic acid binding;GO:0044822//poly(A) RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003743//translation initiation factor activity",-
4534,0,29,0,2,31,0,1,0,14,0,11,0,MTM1;myotubularin 1,GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005829//cytosol;GO:0001726//ruffle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030175//filopodium,GO:0045109//intermediate filament organization;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0015031//protein transport;GO:0008333//endosome to lysosome transport;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0048311//mitochondrion distribution;GO:0044281//small molecule metabolic process;GO:0070584//mitochondrion morphogenesis;GO:0044088//regulation of vacuole organization;GO:0006644//phospholipid metabolic process,"GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0035091//phosphatidylinositol binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0019215//intermediate filament binding",K01108//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
4542,0,0,0,5,0,0,37,3,24,0,35,0,MYO1F;myosin IF,GO:0031941//filamentous actin;GO:0030864//cortical actin cytoskeleton;GO:0016461//unconventional myosin complex,GO:0030335//positive regulation of cell migration;GO:0008152//metabolic process;GO:0032956//regulation of actin cytoskeleton organization;GO:0045088//regulation of innate immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0007162//negative regulation of cell adhesion;GO:0043312//neutrophil degranulation,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003774//motor activity,-
4543,0,0,0,0,0,0,12,0,24,0,0,0,MTNR1A;melatonin receptor 1A,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007623//circadian rhythm;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0007617//mating behavior",GO:0097159//organic cyclic compound binding;GO:0005515//protein binding;GO:0008502//melatonin receptor activity;GO:0042562//hormone binding,K04285//Neuroactive ligand-receptor interaction
4544,0,0,0,0,0,0,0,0,0,12,9,0,MTNR1B;melatonin receptor 1B,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0007268//synaptic transmission;GO:0042593//glucose homeostasis;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0050796//regulation of insulin secretion",GO:0004930//G-protein coupled receptor activity;GO:0008502//melatonin receptor activity;GO:0005515//protein binding,K04286//Neuroactive ligand-receptor interaction
4548,11,28,0,20,66,7,1,0,93,0,1,68,MTR;5-methyltetrahydrofolate-homocysteine methyltransferase,GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0007399//nervous system development;GO:0000096//sulfur amino acid metabolic process;GO:0006766//vitamin metabolic process;GO:0009086//methionine biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0032259//methylation;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0042558//pteridine-containing compound metabolic process;GO:0009235//cobalamin metabolic process,GO:0008270//zinc ion binding;GO:0031419//cobalamin binding;GO:0008705//methionine synthase activity;GO:0008898//S-adenosylmethionine-homocysteine S-methyltransferase activity,K00548//Selenocompound metabolism;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;One carbon pool by folate
4552,0,36,0,35,48,7,25,0,1,0,0,0,MTRR;5-methyltetrahydrofolate-homocysteine methyltransferase reductase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton,GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0009235//cobalamin metabolic process;GO:0009086//methionine biosynthetic process;GO:0046655//folic acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006805//xenobiotic metabolic process;GO:0032259//methylation;GO:0006555//methionine metabolic process;GO:0006306//DNA methylation,"GO:0010181//FMN binding;GO:0030586//[methionine synthase] reductase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0005506//iron ion binding",-
4580,0,0,0,7,20,0,0,0,42,1,16,0,MTX1;metaxin 1,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane,GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion,-,-
4582,0,0,1,0,0,24,0,0,11,0,0,3,"MUC1;mucin 1, cell surface associated",GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane;GO:0000790//nuclear chromatin,"GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0030855//epithelial cell differentiation;GO:0044267//cellular protein metabolic process;GO:0071300//cellular response to retinoic acid;GO:0001666//response to hypoxia;GO:0090240//positive regulation of histone H4 acetylation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0007565//female pregnancy;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding;GO:0002039//p53 binding,-
4583,14,0,0,0,0,34,0,103,75,65,6,0,"MUC2;mucin 2, oligomeric mucus/gel-forming",GO:0070702//inner mucus layer;GO:0005796//Golgi lumen;GO:0070703//outer mucus layer,GO:0030277//maintenance of gastrointestinal epithelium;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding,K10955//Amoebiasis;Vibrio cholerae infection
4584,1,78,51,64,534,0,0,232,140,1,962,1,"MUC3A;mucin 3A, cell surface associated",GO:0016021//integral component of membrane;GO:0005796//Golgi lumen;GO:0005576//extracellular region,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,"GO:0005201//extracellular matrix structural constituent;GO:0030197//extracellular matrix constituent, lubricant activity",-
4585,261,27,1,0,6,37,74,35,69,0,8,52,"MUC4;mucin 4, cell surface associated",GO:0005615//extracellular space;GO:0016020//membrane;GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031982//vesicle,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0007160//cell-matrix adhesion;GO:0030277//maintenance of gastrointestinal epithelium,"GO:0005176//ErbB-2 class receptor binding;GO:0030197//extracellular matrix constituent, lubricant activity",K10955//Amoebiasis;Vibrio cholerae infection
4588,0,0,0,0,17,11,95,52,76,116,25,0,"MUC6;mucin 6, oligomeric mucus/gel-forming",GO:0005796//Golgi lumen;GO:0005576//extracellular region,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0030277//maintenance of gastrointestinal epithelium;GO:0044267//cellular protein metabolic process,GO:0005201//extracellular matrix structural constituent,K10955//Amoebiasis;Vibrio cholerae infection
4589,0,0,0,0,0,0,13,38,0,0,0,0,"MUC7;mucin 7, secreted",GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen,GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,GO:0005515//protein binding,K13909//Salivary secretion
4591,0,3,50,55,125,0,25,0,62,0,55,0,TRIM37;tripartite motif containing 37,GO:0005737//cytoplasm;GO:0016235//aggresome;GO:0048471//perinuclear region of cytoplasm;GO:0005777//peroxisome;GO:0005829//cytosol,GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0046600//negative regulation of centriole replication;GO:0051865//protein autoubiquitination;GO:0070842//aggresome assembly;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042803//protein homodimerization activity;GO:0005164//tumor necrosis factor receptor binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0003682//chromatin binding,K10608//Ubiquitin mediated proteolysis
4593,0,8,0,0,0,0,16,0,37,0,0,0,"MUSK;muscle, skeletal, receptor tyrosine kinase",GO:0045211//postsynaptic membrane;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,"GO:2000541//positive regulation of protein geranylgeranylation;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010628//positive regulation of gene expression;GO:0007275//multicellular organismal development;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043525//positive regulation of neuron apoptotic process;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0007528//neuromuscular junction development;GO:0046777//protein autophosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0007613//memory;GO:0030154//cell differentiation;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0030198//extracellular matrix organization",GO:0005515//protein binding;GO:0005524//ATP binding;GO:0030165//PDZ domain binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity,-
4594,0,29,0,33,51,0,64,0,52,0,17,0,MUT;methylmalonyl CoA mutase,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0009791//post-embryonic development;GO:0044255//cellular lipid metabolic process;GO:0009235//cobalamin metabolic process;GO:0019626//short-chain fatty acid catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006766//vitamin metabolic process;GO:0050667//homocysteine metabolic process,GO:0031419//cobalamin binding;GO:0046872//metal ion binding;GO:0004494//methylmalonyl-CoA mutase activity;GO:0072341//modified amino acid binding,"K01847//Metabolic pathways;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Propanoate metabolism;Microbial metabolism in diverse environments;Glyoxylate and dicarboxylate metabolism"
4595,0,0,0,11,23,0,0,0,23,0,31,0,MUTYH;mutY homolog,GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0045007//depurination;GO:0006298//mismatch repair;GO:0006284//base-excision repair;GO:0006281//DNA repair,"GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0032407//MutSalpha complex binding;GO:0032406//MutLbeta complex binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0032408//MutSbeta complex binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0032405//MutLalpha complex binding",K03575//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Base excision repair;Metabolic pathways;Pentose and glucuronate interconversions
4597,0,0,0,1,1,0,5,111,0,0,3,0,MVD;mevalonate (diphospho) decarboxylase,GO:0005829//cytosol;GO:0005777//peroxisome,"GO:0006695//cholesterol biosynthetic process;GO:0008299//isoprenoid biosynthetic process;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044281//small molecule metabolic process",GO:0042803//protein homodimerization activity;GO:0030544//Hsp70 protein binding;GO:0005524//ATP binding;GO:0004163//diphosphomevalonate decarboxylase activity,K01597//Biosynthesis of secondary metabolites;Metabolic pathways;Terpenoid backbone biosynthesis
4598,0,0,0,0,0,0,17,0,0,0,0,0,MVK;mevalonate kinase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005777//peroxisome,"GO:0016310//phosphorylation;GO:0008299//isoprenoid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019287//isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0050728//negative regulation of inflammatory response",GO:0004496//mevalonate kinase activity;GO:0042802//identical protein binding;GO:0005524//ATP binding,K00869//Peroxisome;Biosynthesis of secondary metabolites;Metabolic pathways;Terpenoid backbone biosynthesis
4599,0,0,0,15,1,0,14,0,75,0,4,0,"MX1;myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol,GO:0060337//type I interferon signaling pathway;GO:0006952//defense response;GO:0045087//innate immune response;GO:0051607//defense response to virus;GO:0007165//signal transduction;GO:0006915//apoptotic process;GO:0006184//GTP catabolic process;GO:0045071//negative regulation of viral genome replication;GO:0034340//response to type I interferon;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding,K14754//Measles;Influenza A
460,0,0,0,0,0,9,53,0,67,0,0,0,ASTN1;astrotactin 1,GO:0005768//endosome;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0007158//neuron cell-cell adhesion;GO:0007626//locomotory behavior;GO:0001764//neuron migration,-,-
4600,0,0,0,0,0,13,0,0,70,0,15,0,MX2;myxovirus (influenza virus) resistance 2 (mouse),GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0005634//nucleus,GO:0006184//GTP catabolic process;GO:0051726//regulation of cell cycle;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0060337//type I interferon signaling pathway;GO:0006952//defense response;GO:0051607//defense response to virus;GO:0051028//mRNA transport;GO:0035455//response to interferon-alpha;GO:0046822//regulation of nucleocytoplasmic transport,GO:0003924//GTPase activity;GO:0005525//GTP binding,K14754//Influenza A;Measles
4601,16,0,0,19,58,0,9,0,0,0,0,0,"MXI1;MAX interactor 1, dimerization protein",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation",GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0003714//transcription corepressor activity,-
4602,16,0,0,2,0,3,44,50,102,3,0,0,MYB;v-myb avian myeloblastosis viral oncogene homolog,GO:0016363//nuclear matrix,"GO:0048566//embryonic digestive tract development;GO:0048872//homeostasis of number of cells;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0007596//blood coagulation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000082//G1/S transition of mitotic cell cycle;GO:0030183//B cell differentiation;GO:0006816//calcium ion transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0045624//positive regulation of T-helper cell differentiation",GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K09420//HTLV-I infection
4603,0,0,0,0,0,0,0,0,47,0,0,0,MYBL1;v-myb avian myeloblastosis viral oncogene homolog-like 1,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding,K09421//HTLV-I infection
4604,62,101,5,195,450,0,35,144,40,0,12,45,"MYBPC1;myosin binding protein C, slow type",GO:0005829//cytosol;GO:0032982//myosin filament;GO:0030016//myofibril,GO:0007155//cell adhesion;GO:0030049//muscle filament sliding,GO:0005515//protein binding;GO:0031432//titin binding;GO:0008307//structural constituent of muscle;GO:0003779//actin binding,-
4605,101,0,0,0,0,6,6,0,8,0,0,0,MYBL2;v-myb avian myeloblastosis viral oncogene homolog-like 2,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0031523//Myb complex;GO:0005634//nucleus,"GO:0090307//spindle assembly involved in mitosis;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000278//mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09421//HTLV-I infection
4606,0,0,0,0,0,27,0,56,86,0,11,0,"MYBPC2;myosin binding protein C, fast type",GO:0032982//myosin filament;GO:0005829//cytosol,GO:0030049//muscle filament sliding;GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0003779//actin binding,-
4607,170,0,11,0,0,0,23,132,40,0,14,0,"MYBPC3;myosin binding protein C, cardiac",GO:0005829//cytosol;GO:0031672//A band;GO:0014705//C zone;GO:0005863//striated muscle myosin thick filament;GO:0030017//sarcomere,GO:0032971//regulation of muscle filament sliding;GO:0045214//sarcomere organization;GO:0006942//regulation of striated muscle contraction;GO:0002027//regulation of heart rate;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0007155//cell adhesion;GO:0060048//cardiac muscle contraction;GO:0032781//positive regulation of ATPase activity;GO:0030049//muscle filament sliding;GO:0003007//heart morphogenesis;GO:0031034//myosin filament assembly,GO:0046872//metal ion binding;GO:0001671//ATPase activator activity;GO:0017022//myosin binding;GO:0042802//identical protein binding;GO:0031432//titin binding;GO:0008307//structural constituent of muscle;GO:0032036//myosin heavy chain binding;GO:0003779//actin binding,K12568//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
4608,1,0,0,0,0,8,23,0,1,0,9,0,MYBPH;myosin binding protein H,GO:0032982//myosin filament,GO:0006942//regulation of striated muscle contraction;GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0008307//structural constituent of muscle,K12568//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
4609,0,0,0,0,0,0,0,0,0,0,24,0,MYC;v-myc avian myelocytomatosis viral oncogene homolog,GO:0005730//nucleolus;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006879//cellular iron ion homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0044346//fibroblast apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000573//positive regulation of DNA biosynthetic process;GO:0034644//cellular response to UV;GO:0000165//MAPK cascade;GO:0060070//canonical Wnt signaling pathway;GO:0010332//response to gamma radiation;GO:0032873//negative regulation of stress-activated MAPK cascade;GO:0035690//cellular response to drug;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0007219//Notch signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051782//negative regulation of cell division;GO:0015671//oxygen transport;GO:0070848//response to growth factor;GO:0048147//negative regulation of fibroblast proliferation;GO:0010468//regulation of gene expression;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0090096//positive regulation of metanephric cap mesenchymal cell proliferation;GO:0045656//negative regulation of monocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0032204//regulation of telomere maintenance;GO:0048146//positive regulation of fibroblast proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007050//cell cycle arrest;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:2001022//positive regulation of response to DNA damage stimulus;GO:0006112//energy reserve metabolic process;GO:0006338//chromatin remodeling;GO:0051276//chromosome organization",GO:0032403//protein complex binding;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0070491//repressing transcription factor binding;GO:0003677//DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0070888//E-box binding,K04377//Endometrial cancer;Thyroid cancer;HTLV-I infection;Jak-STAT signaling pathway;Acute myeloid leukemia;TGF-beta signaling pathway;Transcriptional misregulation in cancer;Chronic myeloid leukemia;Wnt signaling pathway;MAPK signaling pathway;Cell cycle;Epstein-Barr virus infection;Colorectal cancer;ErbB signaling pathway;Bladder cancer;Pathways in cancer;Small cell lung cancer
4610,0,33,0,0,22,10,44,0,25,0,15,0,MYCL;v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
4613,0,0,0,0,14,0,22,0,18,0,23,0,MYCN;v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog,GO:0005634//nucleus;GO:0000785//chromatin,GO:0010942//positive regulation of cell death;GO:0048754//branching morphogenesis of an epithelial tube;GO:0030324//lung development;GO:0042733//embryonic digit morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0001502//cartilage condensation;GO:0048712//negative regulation of astrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K09109//Transcriptional misregulation in cancer
4615,0,1,0,0,1,0,21,3,0,149,10,0,MYD88;myeloid differentiation primary response 88,GO:0043234//protein complex;GO:0014069//postsynaptic density;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0032755//positive regulation of interleukin-6 production;GO:0070555//response to interleukin-1;GO:0006954//inflammatory response;GO:0032740//positive regulation of interleukin-17 production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019221//cytokine-mediated signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0045351//type I interferon biosynthetic process;GO:0044130//negative regulation of growth of symbiont in host;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0002238//response to molecule of fungal origin;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0050727//regulation of inflammatory response;GO:0032494//response to peptidoglycan;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0050830//defense response to Gram-positive bacterium;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0034162//toll-like receptor 9 signaling pathway;GO:0050671//positive regulation of lymphocyte proliferation;GO:0008063//Toll signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0016064//immunoglobulin mediated immune response;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0032747//positive regulation of interleukin-23 production;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0046330//positive regulation of JNK cascade;GO:0009615//response to virus;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway,GO:0005149//interleukin-1 receptor binding;GO:0070976//TIR domain binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0005123//death receptor binding;GO:0005121//Toll binding,K04729//Chagas disease (American trypanosomiasis);Malaria;NF-kappa B signaling pathway;Salmonella infection;African trypanosomiasis;Tuberculosis;Legionellosis;Pertussis;Toll-like receptor signaling pathway;Influenza A;Herpes simplex infection;Toxoplasmosis;Apoptosis;Leishmaniasis;Measles
4616,0,32,1,0,0,0,0,0,21,0,0,0,"GADD45B;growth arrest and DNA-damage-inducible, beta",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006469//negative regulation of protein kinase activity;GO:0000185//activation of MAPKKK activity;GO:1900745//positive regulation of p38MAPK cascade;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0046330//positive regulation of JNK cascade;GO:0006950//response to stress;GO:0051726//regulation of cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0000186//activation of MAPKK activity,GO:0005515//protein binding,K04402//Cell cycle;p53 signaling pathway;NF-kappa B signaling pathway;MAPK signaling pathway
4617,37,0,0,0,0,16,0,0,0,0,0,0,MYF5;myogenic factor 5,GO:0005654//nucleoplasm,GO:0007517//muscle organ development;GO:0048704//embryonic skeletal system morphogenesis;GO:0001502//cartilage condensation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007519//skeletal muscle tissue development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042692//muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001952//regulation of cell-matrix adhesion;GO:0060415//muscle tissue morphogenesis;GO:0042693//muscle cell fate commitment;GO:0043010//camera-type eye development;GO:0001756//somitogenesis;GO:0001503//ossification;GO:0051149//positive regulation of muscle cell differentiation;GO:0035914//skeletal muscle cell differentiation;GO:0030198//extracellular matrix organization,GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0070888//E-box binding,-
4618,0,0,0,0,0,4,0,0,18,0,0,0,MYF6;myogenic factor 6 (herculin),GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042692//muscle cell differentiation;GO:0001756//somitogenesis;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043403//skeletal muscle tissue regeneration;GO:0051149//positive regulation of muscle cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060415//muscle tissue morphogenesis;GO:0042693//muscle cell fate commitment;GO:0007519//skeletal muscle tissue development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0070888//E-box binding,-
4619,165,0,13,0,0,23,25,0,117,0,0,0,"MYH1;myosin, heavy chain 1, skeletal muscle, adult",GO:0031672//A band;GO:0014704//intercalated disc;GO:0032982//myosin filament;GO:0005859//muscle myosin complex,GO:0008152//metabolic process;GO:0006936//muscle contraction,GO:0003779//actin binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003774//motor activity,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
462,0,0,0,0,0,0,19,0,13,0,0,0,"SERPINC1;serpin peptidase inhibitor, clade C (antithrombin), member 1",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0072562//blood microparticle;GO:0005576//extracellular region,"GO:0050728//negative regulation of inflammatory response;GO:0030162//regulation of proteolysis;GO:0007584//response to nutrient;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:2000266//regulation of blood coagulation, intrinsic pathway",GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding;GO:0005515//protein binding,K03911//Complement and coagulation cascades
4620,0,0,0,0,0,13,63,0,31,0,19,0,"MYH2;myosin, heavy chain 2, skeletal muscle, adult",GO:0030016//myofibril;GO:0032982//myosin filament;GO:0005794//Golgi apparatus;GO:0005911//cell-cell junction;GO:0005826//actomyosin contractile ring;GO:0043234//protein complex;GO:0031672//A band;GO:0005829//cytosol;GO:0005859//muscle myosin complex;GO:0030017//sarcomere,GO:0030049//muscle filament sliding;GO:0045087//innate immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0001778//plasma membrane repair;GO:0006936//muscle contraction;GO:0014823//response to activity;GO:0061024//membrane organization;GO:0008152//metabolic process,GO:0000146//microfilament motor activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
4621,248,0,0,0,0,43,37,36,11,0,10,0,"MYH3;myosin, heavy chain 3, skeletal muscle, embryonic",GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0032982//myosin filament;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0045214//sarcomere organization;GO:0003009//skeletal muscle contraction;GO:0060325//face morphogenesis;GO:0007517//muscle organ development;GO:0030048//actin filament-based movement;GO:0030326//embryonic limb morphogenesis;GO:0030049//muscle filament sliding;GO:0006200//ATP catabolic process,"GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0042623//ATPase activity, coupled;GO:0051015//actin filament binding;GO:0000146//microfilament motor activity",K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
4622,183,0,0,0,0,58,20,114,118,0,2,294,"MYH4;myosin, heavy chain 4, skeletal muscle",GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0030016//myofibril;GO:0032982//myosin filament,GO:0006936//muscle contraction;GO:0061024//membrane organization;GO:0006200//ATP catabolic process;GO:0014823//response to activity;GO:0030048//actin filament-based movement;GO:0030049//muscle filament sliding,GO:0003779//actin binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0000146//microfilament motor activity;GO:0003725//double-stranded RNA binding,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
4624,141,0,0,0,0,53,76,120,65,0,9,0,"MYH6;myosin, heavy chain 6, cardiac muscle, alpha",GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0016459//myosin complex;GO:0030016//myofibril;GO:0032982//myosin filament;GO:0001725//stress fiber;GO:0030017//sarcomere;GO:0005634//nucleus;GO:0005859//muscle myosin complex;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005829//cytosol,GO:0002026//regulation of the force of heart contraction;GO:0006200//ATP catabolic process;GO:0007512//adult heart development;GO:0006941//striated muscle contraction;GO:0060420//regulation of heart growth;GO:0030049//muscle filament sliding;GO:0002027//regulation of heart rate;GO:0006936//muscle contraction;GO:0043462//regulation of ATPase activity;GO:0045214//sarcomere organization;GO:0008217//regulation of blood pressure;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0048739//cardiac muscle fiber development;GO:0001701//in utero embryonic development;GO:0030239//myofibril assembly;GO:0030509//BMP signaling pathway;GO:0007522//visceral muscle development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0008016//regulation of heart contraction,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0000146//microfilament motor activity;GO:0016887//ATPase activity;GO:0030898//actin-dependent ATPase activity,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
4625,69,0,0,0,0,0,51,0,125,164,1,0,"MYH7;myosin, heavy chain 7, cardiac muscle, beta",GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005859//muscle myosin complex;GO:0001725//stress fiber;GO:0030017//sarcomere;GO:0005634//nucleus;GO:0032982//myosin filament;GO:0016459//myosin complex;GO:0030018//Z disc;GO:0005737//cytoplasm,GO:0006941//striated muscle contraction;GO:0030049//muscle filament sliding;GO:0006200//ATP catabolic process;GO:0002026//regulation of the force of heart contraction;GO:0007512//adult heart development;GO:0002027//regulation of heart rate;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006936//muscle contraction,GO:0005515//protein binding;GO:0000146//microfilament motor activity;GO:0016887//ATPase activity;GO:0030898//actin-dependent ATPase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
4626,63,0,0,0,0,0,0,7,80,0,3,0,"MYH8;myosin, heavy chain 8, skeletal muscle, perinatal",GO:0005829//cytosol;GO:0032982//myosin filament;GO:0005737//cytoplasm;GO:0030017//sarcomere;GO:0005859//muscle myosin complex,GO:0030049//muscle filament sliding;GO:0006936//muscle contraction;GO:0003009//skeletal muscle contraction;GO:0006200//ATP catabolic process,GO:0005516//calmodulin binding;GO:0008307//structural constituent of muscle;GO:0005524//ATP binding;GO:0000146//microfilament motor activity;GO:0032027//myosin light chain binding;GO:0051015//actin filament binding;GO:0016887//ATPase activity,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
4627,2,39,2,17,143,47,39,59,46,148,5,361,"MYH9;myosin, heavy chain 9, non-muscle",GO:0005886//plasma membrane;GO:0005819//spindle;GO:0005913//cell-cell adherens junction;GO:0043234//protein complex;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030863//cortical cytoskeleton;GO:0001931//uropod;GO:0016020//membrane;GO:0032154//cleavage furrow;GO:0001726//ruffle;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0031594//neuromuscular junction;GO:0005737//cytoplasm;GO:0042641//actomyosin;GO:0097513//myosin II filament;GO:0008305//integrin complex;GO:0005826//actomyosin contractile ring;GO:0008180//COP9 signalosome;GO:0016460//myosin II complex;GO:0001772//immunological synapse;GO:0001725//stress fiber;GO:0005634//nucleus,GO:0006509//membrane protein ectodomain proteolysis;GO:0070527//platelet aggregation;GO:0008360//regulation of cell shape;GO:0031532//actin cytoskeleton reorganization;GO:0015031//protein transport;GO:0007411//axon guidance;GO:0001701//in utero embryonic development;GO:0030048//actin filament-based movement;GO:0001525//angiogenesis;GO:0001768//establishment of T cell polarity;GO:0051295//establishment of meiotic spindle localization;GO:0007520//myoblast fusion;GO:0030224//monocyte differentiation;GO:0000910//cytokinesis;GO:0043534//blood vessel endothelial cell migration;GO:0032796//uropod organization;GO:0000212//meiotic spindle organization;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0031032//actomyosin structure organization;GO:0050900//leukocyte migration;GO:0030220//platelet formation;GO:0007229//integrin-mediated signaling pathway;GO:0006200//ATP catabolic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000146//microfilament motor activity;GO:0042803//protein homodimerization activity;GO:0043531//ADP binding;GO:0051015//actin filament binding;GO:0003774//motor activity;GO:0030898//actin-dependent ATPase activity;GO:0016887//ATPase activity;GO:0043495//protein anchor;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
4628,0,45,2,37,212,0,21,46,57,162,10,2,"MYH10;myosin, heavy chain 10, non-muscle",GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0005819//spindle;GO:0030027//lamellipodium;GO:0070062//extracellular vesicular exosome;GO:0031594//neuromuscular junction;GO:0032154//cleavage furrow;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0042641//actomyosin;GO:0097513//myosin II filament;GO:0043197//dendritic spine;GO:0016459//myosin complex;GO:0030496//midbody;GO:0030424//axon;GO:0016460//myosin II complex;GO:0001725//stress fiber;GO:0005634//nucleus,"GO:0060041//retina development in camera-type eye;GO:0006200//ATP catabolic process;GO:0021670//lateral ventricle development;GO:0031032//actomyosin structure organization;GO:0055015//ventricular cardiac muscle cell development;GO:0007512//adult heart development;GO:0021680//cerebellar Purkinje cell layer development;GO:0001764//neuron migration;GO:0001778//plasma membrane repair;GO:0006887//exocytosis;GO:0021678//third ventricle development;GO:0007155//cell adhesion;GO:0000281//mitotic cytokinesis;GO:0001701//in utero embryonic development;GO:0030048//actin filament-based movement;GO:0006930//substrate-dependent cell migration, cell extension;GO:0021592//fourth ventricle development;GO:0055003//cardiac myofibril assembly;GO:0007097//nuclear migration;GO:0008283//cell proliferation;GO:0007411//axon guidance;GO:0008360//regulation of cell shape;GO:0050885//neuromuscular process controlling balance",GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0051015//actin filament binding;GO:0030898//actin-dependent ATPase activity;GO:0043531//ADP binding;GO:0005515//protein binding;GO:0000146//microfilament motor activity,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
4629,80,280,115,108,138,13,14,238,117,1,218,1,"MYH11;myosin, heavy chain 11, smooth muscle",GO:0005859//muscle myosin complex;GO:0001725//stress fiber;GO:0030485//smooth muscle contractile fiber;GO:0032982//myosin filament;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0005829//cytosol,GO:0030241//skeletal muscle myosin thick filament assembly;GO:0006939//smooth muscle contraction;GO:0008152//metabolic process;GO:0007411//axon guidance;GO:0006936//muscle contraction;GO:0048739//cardiac muscle fiber development;GO:0048251//elastic fiber assembly,GO:0008307//structural constituent of muscle;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding;GO:0003774//motor activity;GO:0005515//protein binding,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
463,89,155,81,96,337,68,78,100,95,0,135,0,ZFHX3;zinc finger homeobox 3,GO:0005739//mitochondrion;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0007420//brain development;GO:0007517//muscle organ development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045664//regulation of neuron differentiation;GO:0045662//negative regulation of myoblast differentiation;GO:0007050//cell cycle arrest;GO:0006355//regulation of transcription, DNA-templated;GO:0045663//positive regulation of myoblast differentiation",GO:0044212//transcription regulatory region DNA binding;GO:0019899//enzyme binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding,-
4632,35,0,0,0,0,28,0,44,11,0,0,0,"MYL1;myosin, light chain 1, alkali; skeletal, fast",GO:0030017//sarcomere;GO:0005859//muscle myosin complex;GO:0005829//cytosol;GO:0030016//myofibril,GO:0006936//muscle contraction;GO:0060048//cardiac muscle contraction;GO:0030049//muscle filament sliding,GO:0005509//calcium ion binding;GO:0008307//structural constituent of muscle,-
4634,1,0,0,0,0,0,0,134,0,8,5,0,"MYL3;myosin, light chain 3, alkali; ventricular, skeletal, slow",GO:0005829//cytosol;GO:0031672//A band;GO:0005859//muscle myosin complex;GO:0030017//sarcomere;GO:0031674//I band,GO:0032781//positive regulation of ATPase activity;GO:0030049//muscle filament sliding;GO:0060048//cardiac muscle contraction;GO:0002026//regulation of the force of heart contraction;GO:0007519//skeletal muscle tissue development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006942//regulation of striated muscle contraction;GO:0008152//metabolic process,GO:0032038//myosin II heavy chain binding;GO:0005509//calcium ion binding;GO:0003774//motor activity;GO:0003785//actin monomer binding;GO:0008307//structural constituent of muscle,K12749//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction
4635,0,0,0,0,0,0,0,0,19,0,0,0,"MYL4;myosin, light chain 4, alkali; atrial, embryonic",GO:0031672//A band;GO:0005829//cytosol;GO:0016459//myosin complex,GO:0060048//cardiac muscle contraction;GO:0030049//muscle filament sliding;GO:0032781//positive regulation of ATPase activity;GO:0002026//regulation of the force of heart contraction,GO:0003785//actin monomer binding;GO:0032038//myosin II heavy chain binding;GO:0051015//actin filament binding;GO:0005509//calcium ion binding,-
4636,0,24,0,0,4,0,13,50,18,0,0,0,"MYL5;myosin, light chain 5, regulatory",GO:0005859//muscle myosin complex,GO:0006937//regulation of muscle contraction,GO:0008307//structural constituent of muscle;GO:0005509//calcium ion binding,K12753//Focal adhesion;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Tight junction
4637,0,210,0,94,335,0,1,0,19,0,1,0,"MYL6;myosin, light chain 6, alkali, smooth muscle and non-muscle",GO:0016461//unconventional myosin complex;GO:0031982//vesicle;GO:0016459//myosin complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0007411//axon guidance;GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0006936//muscle contraction;GO:0007519//skeletal muscle tissue development;GO:0030049//muscle filament sliding,GO:0008307//structural constituent of muscle;GO:0005515//protein binding;GO:0030898//actin-dependent ATPase activity;GO:0005509//calcium ion binding;GO:0003774//motor activity,K12751//Vascular smooth muscle contraction
4638,121,0,0,48,35,87,73,37,109,1,64,578,MYLK;myosin light chain kinase,GO:0032154//cleavage furrow;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0005911//cell-cell junction,GO:0006468//protein phosphorylation;GO:0032060//bleb assembly;GO:0030335//positive regulation of cell migration;GO:0090303//positive regulation of wound healing;GO:0006936//muscle contraction;GO:0007015//actin filament organization;GO:0071476//cellular hypotonic response;GO:0051928//positive regulation of calcium ion transport;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0006939//smooth muscle contraction;GO:0014820//tonic smooth muscle contraction,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0004687//myosin light chain kinase activity;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
4640,81,0,0,0,0,0,14,0,25,0,0,0,MYO1A;myosin IA,GO:0016323//basolateral plasma membrane;GO:0031941//filamentous actin;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0016459//myosin complex;GO:0016328//lateral plasma membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane,GO:0051648//vesicle localization;GO:0008152//metabolic process;GO:0007605//sensory perception of sound;GO:0030033//microvillus assembly,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003774//motor activity,-
4641,105,3,1,24,89,3,80,1,87,0,17,0,MYO1C;myosin IC,GO:0005654//nucleoplasm;GO:0016328//lateral plasma membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0016020//membrane;GO:0060171//stereocilium membrane;GO:0070062//extracellular vesicular exosome;GO:0005903//brush border;GO:0009925//basal plasma membrane;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0016461//unconventional myosin complex;GO:0005643//nuclear pore;GO:0005730//nucleolus;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0045160//myosin I complex;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0005739//mitochondrion,GO:2000810//regulation of tight junction assembly;GO:0008152//metabolic process;GO:0006605//protein targeting;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:0030335//positive regulation of cell migration;GO:0061024//membrane organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006612//protein targeting to membrane;GO:0045087//innate immune response;GO:0038089//positive regulation of cell migration by vascular endothelial growth factor signaling pathway;GO:0051028//mRNA transport;GO:0090314//positive regulation of protein targeting to membrane,GO:0005102//receptor binding;GO:0003779//actin binding;GO:0008022//protein C-terminus binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0003774//motor activity,-
4642,9,2,0,48,134,0,1,52,41,3,0,0,MYO1D;myosin ID,GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0030673//axolemma;GO:0016459//myosin complex;GO:0005790//smooth endoplasmic reticulum,GO:0061502//early endosome to recycling endosome transport;GO:0010923//negative regulation of phosphatase activity;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0030898//actin-dependent ATPase activity;GO:0048306//calcium-dependent protein binding;GO:0000146//microfilament motor activity,-
4643,18,71,42,19,98,20,40,1,44,0,31,288,MYO1E;myosin IE,GO:0005912//adherens junction;GO:0045334//clathrin-coated endocytic vesicle;GO:0015629//actin cytoskeleton;GO:0016459//myosin complex;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0070062//extracellular vesicular exosome,GO:0003094//glomerular filtration;GO:0032836//glomerular basement membrane development;GO:0001701//in utero embryonic development;GO:0030048//actin filament-based movement;GO:0001570//vasculogenesis;GO:0006200//ATP catabolic process;GO:0035166//post-embryonic hemopoiesis;GO:0006897//endocytosis;GO:0072015//glomerular visceral epithelial cell development;GO:0048008//platelet-derived growth factor receptor signaling pathway,"GO:0042623//ATPase activity, coupled;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0000146//microfilament motor activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003774//motor activity;GO:0051015//actin filament binding",-
4644,0,6,1,65,85,9,104,0,141,0,0,0,"MYO5A;myosin VA (heavy chain 12, myoxin)",GO:0032593//insulin-responsive compartment;GO:0035371//microtubule plus-end;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0042470//melanosome;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0016459//myosin complex;GO:0001750//photoreceptor outer segment;GO:0042641//actomyosin;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0030426//growth cone,"GO:0042476//odontogenesis;GO:0030073//insulin secretion;GO:0032402//melanosome transport;GO:0030318//melanocyte differentiation;GO:0007601//visual perception;GO:0006810//transport;GO:0006887//exocytosis;GO:0042552//myelination;GO:0042759//long-chain fatty acid biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0031585//regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0061024//membrane organization;GO:0007268//synaptic transmission;GO:0030048//actin filament-based movement;GO:0042438//melanin biosynthetic process;GO:0016192//vesicle-mediated transport;GO:0032252//secretory granule localization;GO:0032869//cellular response to insulin stimulus;GO:0072659//protein localization to plasma membrane;GO:0051643//endoplasmic reticulum localization;GO:0031987//locomotion involved in locomotory behavior;GO:0042640//anagen;GO:0050808//synapse organization;GO:0015031//protein transport",GO:0017137//Rab GTPase binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0005509//calcium ion binding;GO:0000146//microfilament motor activity;GO:0044822//poly(A) RNA binding,-
4645,67,119,2,61,160,21,27,6,61,189,26,0,MYO5B;myosin VB,GO:0043234//protein complex;GO:0016459//myosin complex;GO:0030659//cytoplasmic vesicle membrane;GO:0070062//extracellular vesicular exosome,GO:0016192//vesicle-mediated transport;GO:0006833//water transport;GO:0008152//metabolic process;GO:0015031//protein transport;GO:0055085//transmembrane transport,GO:0003779//actin binding;GO:0017137//Rab GTPase binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0005515//protein binding;GO:0000146//microfilament motor activity,-
4646,0,0,0,5,0,0,0,0,0,0,0,0,MYO6;myosin VI,"GO:0001726//ruffle;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0030665//clathrin-coated vesicle membrane;GO:0005654//nucleoplasm;GO:0005905//coated pit;GO:0005765//lysosomal membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0045334//clathrin-coated endocytic vesicle;GO:0030424//axon;GO:0005634//nucleus;GO:0016461//unconventional myosin complex;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0031965//nuclear membrane;GO:0043025//neuronal cell body;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0030139//endocytic vesicle;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0048471//perinuclear region of cytoplasm","GO:0048167//regulation of synaptic plasticity;GO:0051046//regulation of secretion;GO:0014047//glutamate secretion;GO:0008152//metabolic process;GO:0006605//protein targeting;GO:0042472//inner ear morphogenesis;GO:0030048//actin filament-based movement;GO:0042493//response to drug;GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0006897//endocytosis;GO:0071257//cellular response to electrical stimulus;GO:0007268//synaptic transmission;GO:0061024//membrane organization;GO:0007416//synapse assembly;GO:0042491//auditory receptor cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006886//intracellular protein transport;GO:0016358//dendrite development;GO:0030330//DNA damage response, signal transduction by p53 class mediator",GO:0043531//ADP binding;GO:0060001//minus-end directed microfilament motor activity;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0051015//actin filament binding;GO:0003774//motor activity,-
4647,0,0,0,0,0,28,21,0,77,19,7,0,MYO7A;myosin VIIA,GO:0005829//cytosol;GO:0032391//photoreceptor connecting cilium;GO:0032420//stereocilium;GO:0042470//melanosome;GO:0045202//synapse;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0031477//myosin VII complex;GO:0016324//apical plasma membrane;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane,GO:0050953//sensory perception of light stimulus;GO:0060088//auditory receptor cell stereocilium organization;GO:0008152//metabolic process;GO:0007040//lysosome organization;GO:0051904//pigment granule transport;GO:0001845//phagolysosome assembly;GO:0048563//post-embryonic organ morphogenesis;GO:0006886//intracellular protein transport;GO:0042462//eye photoreceptor cell development;GO:0006200//ATP catabolic process;GO:0007601//visual perception;GO:0050957//equilibrioception;GO:0007605//sensory perception of sound;GO:0030048//actin filament-based movement,GO:0019904//protein domain specific binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0030898//actin-dependent ATPase activity;GO:0051015//actin filament binding;GO:0043531//ADP binding;GO:0030507//spectrin binding;GO:0000146//microfilament motor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
4648,224,0,0,0,0,33,23,0,77,83,9,1,MYO7B;myosin VIIB,GO:0016459//myosin complex;GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0003779//actin binding;GO:0003774//motor activity,-
4649,45,1,0,26,64,66,12,0,119,1,12,260,MYO9A;myosin IXA,GO:0016461//unconventional myosin complex;GO:0016021//integral component of membrane;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007601//visual perception;GO:0008152//metabolic process,GO:0005096//GTPase activator activity;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003774//motor activity,-
4650,0,1,0,2,1,14,0,87,38,59,35,0,MYO9B;myosin IXB,GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0016459//myosin complex;GO:0032433//filopodium tip;GO:0001726//ruffle;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0031941//filamentous actin,GO:0048246//macrophage chemotaxis;GO:0002548//monocyte chemotaxis;GO:0032011//ARF protein signal transduction;GO:0007266//Rho protein signal transduction;GO:0006200//ATP catabolic process;GO:0032321//positive regulation of Rho GTPase activity;GO:0072673//lamellipodium morphogenesis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0030048//actin filament-based movement;GO:0007264//small GTPase mediated signal transduction;GO:0030010//establishment of cell polarity,GO:0043531//ADP binding;GO:0000146//microfilament motor activity;GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity;GO:0042803//protein homodimerization activity;GO:0043008//ATP-dependent protein binding;GO:0008270//zinc ion binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0051015//actin filament binding;GO:0030898//actin-dependent ATPase activity;GO:0016887//ATPase activity,-
4651,52,16,0,16,120,82,22,143,92,171,18,0,MYO10;myosin X,GO:0005886//plasma membrane;GO:0032433//filopodium tip;GO:0001726//ruffle;GO:0043005//neuron projection;GO:0031527//filopodium membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0016459//myosin complex;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0008360//regulation of cell shape;GO:0022409//positive regulation of cell-cell adhesion;GO:0051489//regulation of filopodium assembly;GO:0007411//axon guidance;GO:0008152//metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0006200//ATP catabolic process;GO:0045087//innate immune response;GO:0030705//cytoskeleton-dependent intracellular transport,"GO:0060002//plus-end directed microfilament motor activity;GO:0030507//spectrin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0051015//actin filament binding;GO:0030898//actin-dependent ATPase activity",K12559//Fc gamma R-mediated phagocytosis
4653,0,39,0,0,5,0,0,0,0,0,0,0,"MYOC;myocilin, trabecular meshwork inducible glucocorticoid response",GO:0005578//proteinaceous extracellular matrix;GO:0031410//cytoplasmic vesicle;GO:0033268//node of Ranvier;GO:0005783//endoplasmic reticulum;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0070062//extracellular vesicular exosome;GO:0005758//mitochondrial intermembrane space;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0031012//extracellular matrix;GO:0005929//cilium;GO:0005615//extracellular space;GO:0005743//mitochondrial inner membrane;GO:0005791//rough endoplasmic reticulum,GO:0038133//ERBB2-ERBB3 signaling pathway;GO:0051497//negative regulation of stress fiber assembly;GO:0014734//skeletal muscle hypertrophy;GO:0001953//negative regulation of cell-matrix adhesion;GO:0001649//osteoblast differentiation;GO:0051496//positive regulation of stress fiber assembly;GO:0060348//bone development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0051901//positive regulation of mitochondrial depolarization;GO:0031175//neuron projection development;GO:0045162//clustering of voltage-gated sodium channels;GO:0051897//positive regulation of protein kinase B signaling;GO:0030335//positive regulation of cell migration;GO:0022011//myelination in peripheral nervous system;GO:0043408//regulation of MAPK cascade;GO:0035024//negative regulation of Rho protein signal transduction;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0051894//positive regulation of focal adhesion assembly,GO:0030971//receptor tyrosine kinase binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0032027//myosin light chain binding;GO:0001968//fibronectin binding,-
4654,0,0,0,0,0,0,0,42,16,0,0,0,MYOD1;myogenic differentiation 1,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0030016//myofibril,"GO:0042693//muscle cell fate commitment;GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0071392//cellular response to estradiol stimulus;GO:0043503//skeletal muscle fiber adaptation;GO:0051149//positive regulation of muscle cell differentiation;GO:0048741//skeletal muscle fiber development;GO:0006366//transcription from RNA polymerase II promoter;GO:0071453//cellular response to oxygen levels;GO:0007519//skeletal muscle tissue development;GO:0007518//myoblast fate determination;GO:0007517//muscle organ development;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006468//protein phosphorylation;GO:0014904//myotube cell development;GO:0043967//histone H4 acetylation;GO:0043484//regulation of RNA splicing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1901741//positive regulation of myoblast fusion;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0043966//histone H3 acetylation;GO:0071385//cellular response to glucocorticoid stimulus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009267//cellular response to starvation;GO:0042692//muscle cell differentiation",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0070888//E-box binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0001047//core promoter binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0035257//nuclear hormone receptor binding;GO:0003713//transcription coactivator activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding,-
4656,0,0,0,0,0,0,0,0,7,0,0,0,MYOG;myogenin (myogenic factor 4),GO:0032993//protein-DNA complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,GO:0048741//skeletal muscle fiber development;GO:0045663//positive regulation of myoblast differentiation;GO:0007049//cell cycle;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0051149//positive regulation of muscle cell differentiation;GO:0071158//positive regulation of cell cycle arrest;GO:0001503//ossification;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0071285//cellular response to lithium ion;GO:1901739//regulation of myoblast fusion;GO:0014873//response to muscle activity involved in regulation of muscle adaptation;GO:0008285//negative regulation of cell proliferation;GO:0014842//regulation of satellite cell proliferation;GO:0042693//muscle cell fate commitment;GO:0071392//cellular response to estradiol stimulus;GO:0042692//muscle cell differentiation;GO:0014737//positive regulation of muscle atrophy;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014891//striated muscle atrophy;GO:0071363//cellular response to growth factor stimulus;GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0007519//skeletal muscle tissue development;GO:0010831//positive regulation of myotube differentiation,GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0001047//core promoter binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0070888//E-box binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
4659,0,0,0,12,96,33,46,4,75,0,0,0,"PPP1R12A;protein phosphatase 1, regulatory subunit 12A",GO:0043292//contractile fiber;GO:0072357//PTW/PP1 phosphatase complex;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0000776//kinetochore,GO:0006470//protein dephosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0030155//regulation of cell adhesion;GO:0035507//regulation of myosin-light-chain-phosphatase activity;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051297//centrosome organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0046822//regulation of nucleocytoplasmic transport;GO:0007067//mitotic nuclear division,GO:0004871//signal transducer activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004857//enzyme inhibitor activity;GO:0071889//14-3-3 protein binding;GO:0019208//phosphatase regulator activity,K06270//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Long-term potentiation;Focal adhesion
466,0,0,0,0,8,0,0,0,5,0,0,0,ATF1;activating transcription factor 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043623//cellular protein complex assembly;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0014070//response to organic cyclic compound;GO:0010976//positive regulation of neuron projection development;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0045740//positive regulation of DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0032025//response to cobalt ion;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway,GO:0032403//protein complex binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K09053//Transcriptional misregulation in cancer;HTLV-I infection
4660,0,13,0,33,26,0,0,31,10,0,9,375,"PPP1R12B;protein phosphatase 1, regulatory subunit 12B",GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0006937//regulation of muscle contraction;GO:0043085//positive regulation of catalytic activity;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007165//signal transduction,GO:0008047//enzyme activator activity,K12329//Vascular smooth muscle contraction
4661,0,0,0,0,0,76,0,54,27,0,7,0,MYT1;myelin transcription factor 1,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development",GO:0008270//zinc ion binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
4664,0,0,1,0,0,0,44,0,89,0,1,0,NAB1;NGFI-A binding protein 1 (EGR1 binding protein 1),GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0042552//myelination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045682//regulation of epidermis development;GO:0001958//endochondral ossification;GO:0014037//Schwann cell differentiation;GO:0006351//transcription, DNA-templated",GO:0008134//transcription factor binding,-
4665,0,0,0,5,5,0,0,0,0,0,0,0,NAB2;NGFI-A binding protein 2 (EGR1 binding protein 2),GO:0005634//nucleus,"GO:0001958//endochondral ossification;GO:0014037//Schwann cell differentiation;GO:0045682//regulation of epidermis development;GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0042552//myelination;GO:0007399//nervous system development",GO:0003714//transcription corepressor activity;GO:0008134//transcription factor binding,-
4666,0,69,9,86,427,28,0,0,44,200,1,0,NACA;nascent polypeptide-associated complex alpha subunit,GO:0005854//nascent polypeptide-associated complex;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0043403//skeletal muscle tissue regeneration;GO:0048742//regulation of skeletal muscle fiber development;GO:1901227//negative regulation of transcription from RNA polymerase II promoter involved in heart development;GO:0016032//viral process;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0003231//cardiac ventricle development;GO:0006355//regulation of transcription, DNA-templated;GO:0061384//heart trabecula morphogenesis;GO:0006351//transcription, DNA-templated;GO:0006412//translation;GO:0015031//protein transport;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis;GO:1901228//positive regulation of transcription from RNA polymerase II promoter involved in heart development",GO:0003713//transcription coactivator activity;GO:0017025//TBP-class protein binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
4668,93,24,0,0,0,0,0,111,41,0,0,0,"NAGA;N-acetylgalactosaminidase, alpha-",GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0005737//cytoplasm,GO:0016052//carbohydrate catabolic process;GO:0009311//oligosaccharide metabolic process;GO:0016139//glycoside catabolic process;GO:0046477//glycosylceramide catabolic process,GO:0008456//alpha-N-acetylgalactosaminidase activity;GO:0042803//protein homodimerization activity;GO:0004557//alpha-galactosidase activity,K01204//Lysosome;Glycosphingolipid biosynthesis - globo series
4669,0,0,0,0,0,12,12,49,29,149,20,0,"NAGLU;N-acetylglucosaminidase, alpha",GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen;GO:0005764//lysosome,GO:0005975//carbohydrate metabolic process;GO:0045475//locomotor rhythm;GO:0046548//retinal rod cell development;GO:0042474//middle ear morphogenesis;GO:0060119//inner ear receptor cell development;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0007040//lysosome organization;GO:0021680//cerebellar Purkinje cell layer development;GO:0007399//nervous system development;GO:0006027//glycosaminoglycan catabolic process,GO:0004561//alpha-N-acetylglucosaminidase activity,K01205//Lysosome;Metabolic pathways;Glycosaminoglycan degradation
467,0,0,0,0,5,25,0,0,38,0,10,0,ATF3;activating transcription factor 3,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0030968//endoplasmic reticulum unfolded protein response;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044267//cellular protein metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006351//transcription, DNA-templated;GO:0006094//gluconeogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity,K09032//HTLV-I infection
4670,0,10,65,33,143,0,0,101,142,0,9,0,HNRNPM;heterogeneous nuclear ribonucleoprotein M,GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0042382//paraspeckles;GO:0005887//integral component of plasma membrane;GO:0016363//nuclear matrix;GO:0031012//extracellular matrix;GO:0005634//nucleus,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0000380//alternative mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0003723//RNA binding,K12887//Spliceosome
4671,18,1,0,0,1,10,0,0,48,0,0,47,"NAIP;NLR family, apoptosis inhibitory protein",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane,GO:0007399//nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0006954//inflammatory response;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0045087//innate immune response,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process,K12807//NOD-like receptor signaling pathway;Legionellosis
4673,0,0,1,35,88,9,1,0,0,0,0,0,NAP1L1;nucleosome assembly protein 1-like 1,GO:0005634//nucleus;GO:0042470//melanosome;GO:0016020//membrane,GO:0008284//positive regulation of cell proliferation;GO:0006334//nucleosome assembly;GO:0006260//DNA replication,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
4674,0,1,0,19,81,0,0,0,12,153,0,0,NAP1L2;nucleosome assembly protein 1-like 2,GO:0005634//nucleus,GO:0006334//nucleosome assembly;GO:2000035//regulation of stem cell division;GO:0071442//positive regulation of histone H3-K14 acetylation;GO:0045666//positive regulation of neuron differentiation;GO:2000617//positive regulation of histone H3-K9 acetylation,GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042393//histone binding,-
4675,0,0,0,0,0,22,0,0,25,117,0,0,NAP1L3;nucleosome assembly protein 1-like 3,GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
4676,0,16,1,45,21,0,0,0,4,0,0,0,NAP1L4;nucleosome assembly protein 1-like 4,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006334//nucleosome assembly,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,-
4677,0,97,1,81,205,0,12,0,0,0,0,0,NARS;asparaginyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006421//asparaginyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0004816//asparagine-tRNA ligase activity;GO:0003676//nucleic acid binding;GO:0005524//ATP binding,K01893//Aminoacyl-tRNA biosynthesis;Ribosome
4678,0,0,0,8,32,0,39,0,27,1,7,0,NASP;nuclear autoantigenic sperm protein (histone-binding),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0005730//nucleolus,GO:0006335//DNA replication-dependent nucleosome assembly;GO:0043486//histone exchange;GO:0007049//cell cycle;GO:0008283//cell proliferation;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006260//DNA replication;GO:0015031//protein transport;GO:0001824//blastocyst development,GO:0042393//histone binding;GO:0051879//Hsp90 protein binding,-
468,0,231,2,51,423,0,0,42,16,0,0,0,ATF4;activating transcription factor 4,GO:0034399//nuclear periphery;GO:0005634//nucleus;GO:0032590//dendrite membrane;GO:0005667//transcription factor complex;GO:0005815//microtubule organizing center;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034976//response to endoplasmic reticulum stress;GO:0006520//cellular amino acid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0044267//cellular protein metabolic process;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006366//transcription from RNA polymerase II promoter;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0006094//gluconeogenesis;GO:0043267//negative regulation of potassium ion transport;GO:0043525//positive regulation of neuron apoptotic process",GO:0008022//protein C-terminus binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding,K04374//MAPK signaling pathway;Protein processing in endoplasmic reticulum;Amphetamine addiction;Neurotrophin signaling pathway;Dopaminergic synapse;Cocaine addiction;GnRH signaling pathway;HTLV-I infection;Cholinergic synapse;Alcoholism;Prostate cancer;Long-term potentiation
4680,0,0,0,0,0,22,18,0,30,0,0,0,CEACAM6;carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen),GO:0031225//anchored component of membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007267//cell-cell signaling;GO:0007165//signal transduction,GO:0005515//protein binding,-
4681,0,0,0,0,0,20,0,0,5,0,25,0,"NBL1;neuroblastoma 1, DAN family BMP antagonist",GO:0005615//extracellular space,GO:0035582//sequestering of BMP in extracellular matrix;GO:0090027//negative regulation of monocyte chemotaxis;GO:0007399//nervous system development;GO:0038098//sequestering of BMP from receptor via BMP binding;GO:0048812//neuron projection morphogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0048263//determination of dorsal identity,GO:0016015//morphogen activity;GO:0036122//BMP binding;GO:0042803//protein homodimerization activity,K01645//Wnt signaling pathway
4682,0,65,1,0,20,0,0,1,6,0,0,0,NUBP1;nucleotide binding protein 1,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0010826//negative regulation of centrosome duplication;GO:0051642//centrosome localization;GO:0072697//protein localization to cell cortex;GO:0006879//cellular iron ion homeostasis;GO:0016226//iron-sulfur cluster assembly;GO:0016049//cell growth,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0051536//iron-sulfur cluster binding",-
4683,0,57,1,40,101,51,0,169,1,141,0,8,NBN;nibrin,"GO:0005654//nucleoplasm;GO:0005657//replication fork;GO:0000784//nuclear chromosome, telomeric region;GO:0035861//site of double-strand break;GO:0030870//Mre11 complex;GO:0005634//nucleus;GO:0016605//PML body;GO:0005730//nucleolus;GO:0042405//nuclear inclusion body","GO:0000723//telomere maintenance;GO:0008283//cell proliferation;GO:0007126//meiotic nuclear division;GO:0097193//intrinsic apoptotic signaling pathway;GO:0032508//DNA duplex unwinding;GO:0050885//neuromuscular process controlling balance;GO:0000077//DNA damage checkpoint;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0007093//mitotic cell cycle checkpoint;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0045190//isotype switching;GO:0001832//blastocyst growth;GO:0031954//positive regulation of protein autophosphorylation;GO:0000724//double-strand break repair via homologous recombination;GO:0007050//cell cycle arrest;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0033674//positive regulation of kinase activity;GO:0006302//double-strand break repair;GO:0006281//DNA repair",GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0003684//damaged DNA binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0047485//protein N-terminus binding,K10867//Homologous recombination
4684,70,0,0,0,1,71,6,168,41,1,37,0,NCAM1;neural cell adhesion molecule 1,GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,GO:0007411//axon guidance;GO:0019221//cytokine-mediated signaling pathway;GO:0007155//cell adhesion;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0030198//extracellular matrix organization,GO:0042802//identical protein binding,K06491//Prion diseases;Cell adhesion molecules (CAMs)
4685,0,0,0,0,15,0,0,0,16,4,0,0,NCAM2;neural cell adhesion molecule 2,GO:0030424//axon;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007413//axonal fasciculation;GO:0007608//sensory perception of smell;GO:0007158//neuron cell-cell adhesion,-,K06491//Cell adhesion molecules (CAMs);Prion diseases
4686,0,2,21,59,90,11,0,20,103,0,39,0,"NCBP1;nuclear cap binding protein subunit 1, 80kDa",GO:0030529//ribonucleoprotein complex;GO:0005845//mRNA cap binding complex;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005846//nuclear cap binding complex,"GO:0034660//ncRNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0045292//mRNA cis splicing, via spliceosome;GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0016071//mRNA metabolic process;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0006379//mRNA cleavage;GO:0006370//7-methylguanosine mRNA capping;GO:0016070//RNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0031047//gene silencing by RNA;GO:0006446//regulation of translational initiation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006406//mRNA export from nucleus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000339//RNA cap binding;GO:0003723//RNA binding,K12882//RNA transport;mRNA surveillance pathway;Spliceosome
4688,0,0,0,0,0,6,0,0,22,114,0,0,NCF2;neutrophil cytosolic factor 2,GO:0032010//phagolysosome;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0001669//acrosomal vesicle;GO:0043020//NADPH oxidase complex,"GO:0043525//positive regulation of neuron apoptotic process;GO:0032496//response to lipopolysaccharide;GO:0014823//response to activity;GO:0045777//positive regulation of blood pressure;GO:0006801//superoxide metabolic process;GO:0009749//response to glucose;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0034616//response to laminar fluid shear stress;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0055093//response to hyperoxia;GO:0006968//cellular defense response;GO:0042554//superoxide anion generation;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0090382//phagosome maturation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051701//interaction with host;GO:0045730//respiratory burst;GO:0032870//cellular response to hormone stimulus;GO:0007568//aging;GO:0032570//response to progesterone",GO:0008022//protein C-terminus binding;GO:0048365//Rac GTPase binding;GO:0005515//protein binding;GO:0009055//electron carrier activity,K08010//Leukocyte transendothelial migration;Phagosome;Leishmaniasis;Osteoclast differentiation
4689,0,0,0,0,0,0,0,1,34,0,9,485,"NCF4;neutrophil cytosolic factor 4, 40kDa",GO:0032010//phagolysosome;GO:0043020//NADPH oxidase complex;GO:0016020//membrane;GO:0005829//cytosol;GO:0010008//endosome membrane,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006955//immune response;GO:0055114//oxidation-reduction process;GO:0043085//positive regulation of catalytic activity;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051701//interaction with host;GO:0090382//phagosome maturation",GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding,K08012//Leukocyte transendothelial migration;Osteoclast differentiation;Leishmaniasis;Phagosome
4690,46,0,0,27,1,0,0,0,45,0,0,0,NCK1;NCK adaptor protein 1,GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0012506//vesicle membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0051707//response to other organism;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0007172//signal complex assembly;GO:0006469//negative regulation of protein kinase activity;GO:0042110//T cell activation;GO:0007411//axon guidance;GO:0006417//regulation of translation;GO:0030838//positive regulation of actin filament polymerization;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016477//cell migration;GO:0050852//T cell receptor signaling pathway;GO:0030032//lamellipodium assembly;GO:0007015//actin filament organization;GO:0060548//negative regulation of cell death,GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity;GO:0005102//receptor binding;GO:0030971//receptor tyrosine kinase binding;GO:0030159//receptor signaling complex scaffold activity;GO:0019904//protein domain specific binding,K07365//Axon guidance;T cell receptor signaling pathway;ErbB signaling pathway;Pathogenic Escherichia coli infection
4691,0,46,0,113,174,0,0,0,14,0,6,0,NCL;nucleolin,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005938//cell cortex;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0001525//angiogenesis;GO:1901838//positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0042802//identical protein binding;GO:0008022//protein C-terminus binding;GO:0042162//telomeric DNA binding;GO:0003723//RNA binding,K11294//Pathogenic Escherichia coli infection
4692,180,0,0,0,0,10,0,1,22,185,0,0,"NDN;necdin, melanoma antigen (MAGE) family member",GO:0043204//perikaryon;GO:0005829//cytosol;GO:0005813//centrosome;GO:0005634//nucleus;GO:0042995//cell projection,"GO:0007399//nervous system development;GO:0001764//neuron migration;GO:0071514//genetic imprinting;GO:0009791//post-embryonic development;GO:0019233//sensory perception of pain;GO:0008285//negative regulation of cell proliferation;GO:0007417//central nervous system development;GO:0048675//axon extension;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0008347//glial cell migration;GO:0003016//respiratory system process;GO:0048871//multicellular organismal homeostasis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007413//axonal fasciculation",GO:0043015//gamma-tubulin binding;GO:0003677//DNA binding,K12464//Neurotrophin signaling pathway
4693,0,0,0,0,0,0,23,72,0,0,0,0,NDP;Norrie disease (pseudoglioma),GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031012//extracellular matrix,"GO:0007399//nervous system development;GO:0001890//placenta development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0008283//cell proliferation;GO:0060070//canonical Wnt signaling pathway;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0007033//vacuole organization;GO:0007267//cell-cell signaling;GO:0035426//extracellular matrix-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity;GO:0008083//growth factor activity,-
4694,0,17,0,37,45,0,0,0,0,0,6,0,"NDUFA1;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,"GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03945//Metabolic pathways;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation
4695,0,42,0,9,12,0,0,0,0,13,0,0,"NDUFA2;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0031966//mitochondrial membrane,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03946//Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease;Metabolic pathways
4696,0,0,0,0,15,0,0,0,0,0,6,1,"NDUFA3;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa",GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03947//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
4697,0,108,2,28,77,0,16,0,6,0,0,0,"NDUFA4;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005751//mitochondrial respiratory chain complex IV,"GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0004129//cytochrome-c oxidase activity;GO:0032403//protein complex binding;GO:0005515//protein binding,K03948//Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
4698,0,74,1,101,431,7,33,57,23,0,0,0,"NDUFA5;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03949//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
47,0,78,7,168,541,0,28,0,45,0,35,0,ACLY;ATP citrate lyase,GO:0009346//citrate lyase complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0015936//coenzyme A metabolic process;GO:0031325//positive regulation of cellular metabolic process;GO:0006101//citrate metabolic process;GO:0044262//cellular carbohydrate metabolic process;GO:0006112//energy reserve metabolic process;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0008610//lipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process,GO:0048037//cofactor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0003878//ATP citrate synthase activity;GO:0004775//succinate-CoA ligase (ADP-forming) activity,K01648//Microbial metabolism in diverse environments;Metabolic pathways;Citrate cycle (TCA cycle);Biosynthesis of secondary metabolites
4700,0,0,0,11,106,0,0,0,8,0,32,0,"NDUFA6;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa",GO:0031966//mitochondrial membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0044281//small molecule metabolic process;GO:0006979//response to oxidative stress;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03950//Metabolic pathways;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease
4701,0,1,0,0,0,0,0,0,22,0,0,0,"NDUFA7;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03951//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
4702,0,0,0,10,0,0,27,0,0,0,0,0,"NDUFA8;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa",GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0032403//protein complex binding,K03952//Metabolic pathways;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease
4703,87,11,40,0,31,103,111,0,253,123,40,0,NEB;nebulin,GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0007525//somatic muscle development;GO:0030049//muscle filament sliding;GO:0007517//muscle organ development,GO:0008307//structural constituent of muscle;GO:0003779//actin binding;GO:0005515//protein binding,-
4704,124,0,0,10,15,0,6,15,20,0,0,0,"NDUFA9;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0031966//mitochondrial membrane;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006814//sodium ion transport;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0050662//coenzyme binding;GO:0032403//protein complex binding;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding,K03953//Metabolic pathways;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease
4705,0,0,0,1,51,0,22,0,24,1,0,248,"NDUFA10;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain;GO:0042493//response to drug;GO:0009165//nucleotide biosynthetic process",GO:0005524//ATP binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0019206//nucleoside kinase activity,K03954//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
4706,0,27,1,12,0,0,0,47,0,0,0,0,"NDUFAB1;NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa",GO:0005759//mitochondrial matrix;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0031966//mitochondrial membrane,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0009249//protein lipoylation;GO:0006633//fatty acid biosynthetic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0005504//fatty acid binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0005509//calcium ion binding;GO:0000036//ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process,K03955//Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease;Metabolic pathways
4708,0,0,0,5,31,0,0,0,0,0,0,0,"NDUFB2;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03958//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
4709,0,0,0,0,92,7,0,0,0,0,0,0,"NDUFB3;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03959//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
471,0,0,0,15,17,21,16,2,65,0,0,0,ATIC;5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0046452//dihydrofolate metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0021549//cerebellum development;GO:0031100//organ regeneration;GO:0009116//nucleoside metabolic process;GO:0010035//response to inorganic substance;GO:0046654//tetrahydrofolate biosynthetic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0021987//cerebral cortex development;GO:0003360//brainstem development;GO:0006139//nucleobase-containing compound metabolic process,GO:0042803//protein homodimerization activity;GO:0004643//phosphoribosylaminoimidazolecarboxamide formyltransferase activity;GO:0003937//IMP cyclohydrolase activity,K00602//Purine metabolism;Biosynthesis of secondary metabolites;Homologous recombination;One carbon pool by folate;Metabolic pathways
4710,0,0,0,5,32,0,0,0,0,28,0,0,"NDUFB4;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa",GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane,"GO:0044237//cellular metabolic process;GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03960//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
4711,0,0,0,14,87,0,0,0,28,0,0,0,"NDUFB5;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa",GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03961//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
4712,0,0,0,10,45,11,0,0,16,0,0,0,"NDUFB6;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa",GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03962//Metabolic pathways;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation
4713,0,0,20,1,2,0,19,1,0,0,0,309,"NDUFB7;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa",GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03963//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
4714,0,32,0,10,66,0,0,3,53,0,0,0,"NDUFB8;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03964//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
4715,0,0,0,0,14,2,0,0,0,0,0,0,"NDUFB9;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0007605//sensory perception of sound;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03965//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
4716,0,14,0,10,22,0,0,0,0,0,0,0,"NDUFB10;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,"GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0005515//protein binding,K03966//Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways
4717,17,0,0,13,78,0,11,0,0,0,0,0,"NDUFC1;NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03967//Metabolic pathways;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease
4718,0,1,0,0,22,0,20,0,3,0,0,0,"NDUFC2;NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,"GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03968//Metabolic pathways;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease
4719,0,40,1,42,104,0,18,33,44,0,3,0,"NDUFS1;NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space,"GO:0046034//ATP metabolic process;GO:0045333//cellular respiration;GO:0051881//regulation of mitochondrial membrane potential;GO:0044281//small molecule metabolic process;GO:0072593//reactive oxygen species metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain;GO:0008637//apoptotic mitochondrial changes","GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0009055//electron carrier activity;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity",K03934//Metabolic pathways;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease
472,85,1,2,46,69,64,29,31,16,4,3,0,ATM;ATM serine/threonine kinase,"GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0005819//spindle","GO:0030889//negative regulation of B cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0006302//double-strand break repair;GO:0007165//signal transduction;GO:0006975//DNA damage induced protein phosphorylation;GO:0001666//response to hypoxia;GO:0090399//replicative senescence;GO:0002331//pre-B cell allelic exclusion;GO:0043065//positive regulation of apoptotic process;GO:0071044//histone mRNA catabolic process;GO:0000724//double-strand break repair via homologous recombination;GO:0006468//protein phosphorylation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0010212//response to ionizing radiation;GO:0001756//somitogenesis;GO:0051402//neuron apoptotic process;GO:0000723//telomere maintenance;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0035404//histone-serine phosphorylation;GO:0007050//cell cycle arrest;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0007094//mitotic spindle assembly checkpoint;GO:0007131//reciprocal meiotic recombination;GO:0071480//cellular response to gamma radiation;GO:0042159//lipoprotein catabolic process;GO:0007507//heart development;GO:0048599//oocyte development;GO:0043525//positive regulation of neuron apoptotic process;GO:0007420//brain development;GO:0072434//signal transduction involved in mitotic G2 DNA damage checkpoint",GO:0003677//DNA binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0035174//histone serine kinase activity;GO:0004677//DNA-dependent protein kinase activity;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0046983//protein dimerization activity;GO:0047485//protein N-terminus binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K04728//p53 signaling pathway;Transcriptional misregulation in cancer;Cell cycle;Apoptosis;HTLV-I infection;NF-kappa B signaling pathway
4720,150,25,0,0,20,1,0,4,31,0,0,0,"NDUFS2;NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)",GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain","GO:0051287//NAD binding;GO:0003954//NADH dehydrogenase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0009055//electron carrier activity;GO:0048038//quinone binding",K03935//Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease;Metabolic pathways
4722,0,1,0,1,1,8,0,19,19,0,0,0,"NDUFS3;NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)",GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus,"GO:0030308//negative regulation of cell growth;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0021762//substantia nigra development;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain",GO:0003954//NADH dehydrogenase activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron carrier activity;GO:0005515//protein binding,K03936//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
4723,0,1,0,2,1,0,0,1,4,0,0,0,"NDUFV1;NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process","GO:0051539//4 iron, 4 sulfur cluster binding;GO:0010181//FMN binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0051287//NAD binding;GO:0046872//metal ion binding",K03942//Metabolic pathways;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation
4724,0,22,0,25,17,0,0,0,20,0,0,0,"NDUFS4;NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)",GO:0005739//mitochondrion;GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0045333//cellular respiration;GO:0048146//positive regulation of fibroblast proliferation;GO:0001932//regulation of protein phosphorylation;GO:0019933//cAMP-mediated signaling;GO:0007420//brain development;GO:0022904//respiratory electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0051591//response to cAMP;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0072593//reactive oxygen species metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03937//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
4725,0,1,1,9,89,0,0,0,0,0,0,0,"NDUFS5;NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion,"GO:0022904//respiratory electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity,K03938//Metabolic pathways;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease
4726,0,0,0,7,8,0,0,0,9,0,5,0,"NDUFS6;NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane,"GO:0061458//reproductive system development;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0072358//cardiovascular system development;GO:0022904//respiratory electron transport chain;GO:0070584//mitochondrion morphogenesis;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0010259//multicellular organismal aging;GO:0006631//fatty acid metabolic process;GO:0006936//muscle contraction;GO:0035264//multicellular organism growth",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0009055//electron carrier activity,K03939//Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways
4728,0,2,0,0,1,0,0,0,27,0,0,0,"NDUFS8;NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,"GO:0044237//cellular metabolic process;GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0003954//NADH dehydrogenase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0046872//metal ion binding",K03941//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
4729,0,14,0,9,47,0,16,0,14,0,0,0,"NDUFV2;NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa",GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0045272//plasma membrane respiratory chain complex I,"GO:0044237//cellular metabolic process;GO:0007399//nervous system development;GO:0048738//cardiac muscle tissue development;GO:0044281//small molecule metabolic process;GO:0022904//respiratory electron transport chain;GO:0006120//mitochondrial electron transport, NADH to ubiquinone","GO:0009055//electron carrier activity;GO:0046872//metal ion binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0051537//2 iron, 2 sulfur cluster binding",K03943//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
473,0,54,2,50,374,27,80,0,63,0,9,0,RERE;arginine-glutamic acid dipeptide (RE) repeats,GO:0000118//histone deacetylase complex;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0007275//multicellular organismal development;GO:0006607//NLS-bearing protein import into nucleus;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0008267//poly-glutamine tract binding,-
4731,0,0,0,1,6,0,0,1,0,0,2,0,"NDUFV3;NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0044822//poly(A) RNA binding,K03944//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
4733,0,16,0,26,120,0,0,0,10,0,0,0,DRG1;developmentally regulated GTP binding protein 1,GO:0016020//membrane;GO:0005844//polysome;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005525//GTP binding,-
4734,422,0,0,23,12,0,6,0,71,0,0,0,"NEDD4;neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0016327//apicolateral plasma membrane;GO:0000151//ubiquitin ligase complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0000785//chromatin,GO:0019089//transmission of virus;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0003197//endocardial cushion development;GO:0006513//protein monoubiquitination;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:0042110//T cell activation;GO:0044111//development involved in symbiotic interaction;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0050847//progesterone receptor signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0051592//response to calcium ion;GO:0003151//outflow tract morphogenesis;GO:0010766//negative regulation of sodium ion transport;GO:0031623//receptor internalization;GO:0002250//adaptive immune response;GO:0046824//positive regulation of nucleocytoplasmic transport;GO:0034644//cellular response to UV;GO:0050807//regulation of synapse organization;GO:0042391//regulation of membrane potential;GO:0016567//protein ubiquitination;GO:0006622//protein targeting to lysosome;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032801//receptor catabolic process;GO:0007528//neuromuscular junction development;GO:0031175//neuron projection development;GO:0007041//lysosomal transport;GO:0045732//positive regulation of protein catabolic process;GO:0010768//negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage;GO:0048814//regulation of dendrite morphogenesis;GO:0070534//protein K63-linked ubiquitination;GO:0042921//glucocorticoid receptor signaling pathway;GO:0034765//regulation of ion transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0048514//blood vessel morphogenesis,GO:0019904//protein domain specific binding;GO:0070064//proline-rich region binding;GO:0016874//ligase activity;GO:0050815//phosphoserine binding;GO:0070063//RNA polymerase binding;GO:0043130//ubiquitin binding;GO:0031698//beta-2 adrenergic receptor binding;GO:0019871//sodium channel inhibitor activity;GO:0005515//protein binding;GO:0050816//phosphothreonine binding;GO:0004842//ubiquitin-protein transferase activity,K10591//Endocytosis;Ubiquitin mediated proteolysis;Epstein-Barr virus infection
4735,1,872,1085,655,1187,20,15,339,254,0,536,0,SEPT2;septin 2,GO:0031105//septin complex;GO:0060170//ciliary membrane;GO:0005819//spindle;GO:0015629//actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0032154//cleavage furrow;GO:0000777//condensed chromosome kinetochore;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0000145//exocyst;GO:0005730//nucleolus;GO:0035869//ciliary transition zone;GO:0030496//midbody;GO:0005634//nucleus,GO:0032880//regulation of protein localization;GO:0007224//smoothened signaling pathway;GO:0042384//cilium assembly;GO:0050790//regulation of catalytic activity;GO:0007067//mitotic nuclear division;GO:0031175//neuron projection development;GO:0002036//regulation of L-glutamate transport,GO:0032947//protein complex scaffold;GO:0005525//GTP binding;GO:0030234//enzyme regulator activity;GO:0005515//protein binding,K04557//Parkinson's disease
4736,0,571,8,144,785,0,1,0,13,0,0,0,RPL10A;ribosomal protein L10a,GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit,"GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0009653//anatomical structure morphogenesis;GO:0019083//viral transcription;GO:0006413//translational initiation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02865//Ribosome
4738,0,24,0,0,26,0,0,0,0,0,0,0,"NEDD8;neural precursor cell expressed, developmentally down-regulated 8",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005634//nucleus,GO:0045116//protein neddylation;GO:0008104//protein localization;GO:0006508//proteolysis;GO:0009653//anatomical structure morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0014070//response to organic cyclic compound,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,-
4739,0,0,0,0,9,11,13,0,12,0,0,0,"NEDD9;neural precursor cell expressed, developmentally down-regulated 9",GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005819//spindle;GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0000922//spindle pole;GO:0005925//focal adhesion,GO:0040008//regulation of growth;GO:0007067//mitotic nuclear division;GO:0051017//actin filament bundle assembly;GO:0007155//cell adhesion;GO:0007010//cytoskeleton organization;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway,GO:0005515//protein binding,K05726//Chemokine signaling pathway;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Focal adhesion;Leukocyte transendothelial migration
4741,0,0,0,0,0,7,25,0,8,0,0,0,"NEFM;neurofilament, medium polypeptide",GO:0005883//neurofilament;GO:0097418//neurofibrillary tangle;GO:0031594//neuromuscular junction;GO:0030424//axon,GO:0033693//neurofilament bundle assembly;GO:0000226//microtubule cytoskeleton organization;GO:0031133//regulation of axon diameter;GO:0008088//axon cargo transport,GO:0005200//structural constituent of cytoskeleton;GO:0008017//microtubule binding;GO:0005515//protein binding,K04573//Amyotrophic lateral sclerosis (ALS)
474170,0,0,0,0,11,1,0,58,20,1,13,0,"LRRC37A2;leucine rich repeat containing 37, member A2",GO:0016021//integral component of membrane,-,-,K04306//Neuroactive ligand-receptor interaction;K06839//Axon guidance
474338,0,0,0,1,1,0,0,0,0,0,0,0,SUMO1P3;SUMO1 pseudogene 3 (functional),-,-,-,K12160//RNA transport
474343,0,0,0,0,1,0,0,0,0,0,0,0,"SPIN2B;spindlin family, member 2B",GO:0005634//nucleus,GO:0007049//cell cycle;GO:0051726//regulation of cell cycle;GO:0006915//apoptotic process;GO:0007276//gamete generation,-,-
474344,0,0,0,0,0,14,1,0,4,0,0,0,"GIMAP6;GTPase, IMAP family member 6",GO:0005829//cytosol,-,GO:0005525//GTP binding,K05305//Amino sugar and nucleotide sugar metabolism;Fructose and mannose metabolism;Metabolic pathways
474354,0,0,0,0,0,2,10,0,1,0,0,0,LRRC18;leucine rich repeat containing 18,GO:0005737//cytoplasm,-,-,K10130//p53 signaling pathway;NF-kappa B signaling pathway
4744,0,292,4,269,1704,0,6,43,56,1,0,0,"NEFH;neurofilament, heavy polypeptide",GO:0005737//cytoplasm;GO:0097418//neurofibrillary tangle;GO:0005883//neurofilament;GO:0005739//mitochondrion;GO:0030424//axon,GO:0007409//axonogenesis;GO:0033693//neurofilament bundle assembly;GO:0008219//cell death;GO:0000226//microtubule cytoskeleton organization;GO:1902513//regulation of organelle transport along microtubule;GO:0048936//peripheral nervous system neuron axonogenesis;GO:0061564//axon development;GO:0030031//cell projection assembly,"GO:0008017//microtubule binding;GO:0045502//dynein binding;GO:0030674//protein binding, bridging;GO:0019901//protein kinase binding;GO:0005198//structural molecule activity;GO:0019894//kinesin binding;GO:0005200//structural constituent of cytoskeleton",K04574//Amyotrophic lateral sclerosis (ALS)
4745,81,0,0,0,0,48,0,0,58,0,3,96,NELL1;NEL-like 1 (chicken),GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0005576//extracellular region,GO:0030154//cell differentiation;GO:0033689//negative regulation of osteoblast proliferation;GO:0010468//regulation of gene expression;GO:2000599//negative regulation of cyclin catabolic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0007399//nervous system development;GO:0030501//positive regulation of bone mineralization,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
4747,0,0,0,2,21,20,45,0,11,0,0,0,"NEFL;neurofilament, light polypeptide",GO:0033596//TSC1-TSC2 complex;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005883//neurofilament;GO:0030424//axon,GO:0051412//response to corticosterone;GO:0000226//microtubule cytoskeleton organization;GO:0007268//synaptic transmission;GO:0031133//regulation of axon diameter;GO:0014012//peripheral nervous system axon regeneration;GO:0043434//response to peptide hormone;GO:0045109//intermediate filament organization;GO:0019896//axon transport of mitochondrion;GO:0040011//locomotion;GO:0043524//negative regulation of neuron apoptotic process;GO:0050772//positive regulation of axonogenesis;GO:0008090//retrograde axon cargo transport;GO:0051258//protein polymerization;GO:0050885//neuromuscular process controlling balance;GO:0033693//neurofilament bundle assembly;GO:0008219//cell death;GO:0009636//response to toxic substance;GO:0008089//anterograde axon cargo transport;GO:0048812//neuron projection morphogenesis,"GO:0043274//phospholipase binding;GO:0005200//structural constituent of cytoskeleton;GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0030674//protein binding, bridging;GO:0005515//protein binding",K04572//Amyotrophic lateral sclerosis (ALS)
4750,0,0,2,70,56,42,22,0,106,0,0,0,NEK1;NIMA-related kinase 1,GO:0000242//pericentriolar material;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0006974//cellular response to DNA damage stimulus;GO:0007067//mitotic nuclear division;GO:0010212//response to ionizing radiation;GO:0042384//cilium assembly;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity,-
4751,75,0,0,0,0,8,11,0,4,0,3,0,NEK2;NIMA-related kinase 2,GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0000794//condensed nuclear chromosome;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0030496//midbody;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005634//nucleus,GO:0001824//blastocyst development;GO:0007126//meiotic nuclear division;GO:0007088//regulation of mitosis;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0090307//spindle assembly involved in mitosis;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0051299//centrosome separation;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0000070//mitotic sister chromatid segregation;GO:0046777//protein autophosphorylation;GO:0007067//mitotic nuclear division;GO:0051225//spindle assembly;GO:0043392//negative regulation of DNA binding;GO:0046602//regulation of mitotic centrosome separation,GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0005524//ATP binding,-
4752,0,0,0,0,6,10,9,0,10,0,1,0,NEK3;NIMA-related kinase 3,GO:0030424//axon;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0007067//mitotic nuclear division,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
4753,84,0,0,0,0,30,0,0,50,0,0,0,NELL2;NEL-like 2 (chicken),GO:0005576//extracellular region,-,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
4756,0,66,0,5,40,24,14,0,46,5,0,0,NEO1;neogenin 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0042692//muscle cell differentiation;GO:0055072//iron ion homeostasis;GO:0051149//positive regulation of muscle cell differentiation;GO:0007520//myoblast fusion",GO:0004872//receptor activity;GO:0045296//cadherin binding,K06766//Cell adhesion molecules (CAMs)
4759,0,0,0,0,0,0,0,0,8,0,0,0,NEU2;sialidase 2 (cytosolic sialidase),GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0006689//ganglioside catabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0009313//oligosaccharide catabolic process;GO:0006665//sphingolipid metabolic process,GO:0052796//exo-alpha-(2->8)-sialidase activity;GO:0052794//exo-alpha-(2->3)-sialidase activity;GO:0052795//exo-alpha-(2->6)-sialidase activity,K12357//Other glycan degradation;Sphingolipid metabolism
476,0,39,50,71,145,14,0,2,75,0,37,0,"ATP1A1;ATPase, Na+/K+ transporting, alpha 1 polypeptide",GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005901//caveola;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0031982//vesicle;GO:0016324//apical plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0043234//protein complex;GO:0042383//sarcolemma,GO:0006883//cellular sodium ion homeostasis;GO:0060081//membrane hyperpolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0042493//response to drug;GO:0010107//potassium ion import;GO:0045989//positive regulation of striated muscle contraction;GO:0031947//negative regulation of glucocorticoid biosynthetic process;GO:0055085//transmembrane transport;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0086009//membrane repolarization;GO:0086004//regulation of cardiac muscle cell contraction;GO:0002028//regulation of sodium ion transport;GO:0016311//dephosphorylation;GO:0002026//regulation of the force of heart contraction;GO:0006754//ATP biosynthetic process;GO:0045822//negative regulation of heart contraction;GO:0030007//cellular potassium ion homeostasis;GO:0045823//positive regulation of heart contraction;GO:0071260//cellular response to mechanical stimulus;GO:0034220//ion transmembrane transport;GO:0008217//regulation of blood pressure,GO:0005515//protein binding;GO:0016791//phosphatase activity;GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0043531//ADP binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0019901//protein kinase binding;GO:0030506//ankyrin binding;GO:0030955//potassium ion binding;GO:0031402//sodium ion binding;GO:0051087//chaperone binding;GO:0019904//protein domain specific binding;GO:0005524//ATP binding,K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
4760,0,0,0,0,0,0,0,0,18,0,0,0,NEUROD1;neuronal differentiation 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021542//dentate gyrus development;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0045597//positive regulation of cell differentiation;GO:0043065//positive regulation of apoptotic process;GO:0021549//cerebellum development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042493//response to drug;GO:0035883//enteroendocrine cell differentiation;GO:0050796//regulation of insulin secretion;GO:0035881//amacrine cell differentiation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0006913//nucleocytoplasmic transport;GO:0009952//anterior/posterior pattern specification;GO:0030073//insulin secretion;GO:0022008//neurogenesis;GO:0031018//endocrine pancreas development;GO:0045666//positive regulation of neuron differentiation;GO:0048839//inner ear development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0071333//cellular response to glucose stimulus;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0007263//nitric oxide mediated signal transduction;GO:0071156//regulation of cell cycle arrest;GO:0009749//response to glucose;GO:0060730//regulation of intestinal epithelial structure maintenance;GO:0048562//embryonic organ morphogenesis;GO:0042593//glucose homeostasis;GO:0003329//pancreatic PP cell fate commitment;GO:0006351//transcription, DNA-templated;GO:0003326//pancreatic A cell fate commitment",GO:0003713//transcription coactivator activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003690//double-stranded DNA binding;GO:0070888//E-box binding;GO:0008134//transcription factor binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K08033//Maturity onset diabetes of the young
4761,0,0,0,0,0,0,0,0,23,0,0,0,NEUROD2;neuronal differentiation 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:2000297//negative regulation of synapse maturation;GO:0016567//protein ubiquitination;GO:0008306//associative learning;GO:0071277//cellular response to calcium ion;GO:0090129//positive regulation of synapse maturation;GO:0048666//neuron development;GO:0071257//cellular response to electrical stimulus;GO:0031915//positive regulation of synaptic plasticity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007399//nervous system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050850//positive regulation of calcium-mediated signaling;GO:0045666//positive regulation of neuron differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001662//behavioral fear response;GO:0021695//cerebellar cortex development",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0070888//E-box binding,-
4762,0,0,0,0,0,0,0,1,0,163,0,0,NEUROG1;neurogenin 1,GO:0043204//perikaryon;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045666//positive regulation of neuron differentiation;GO:0042472//inner ear morphogenesis;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030182//neuron differentiation;GO:0031536//positive regulation of exit from mitosis;GO:0006351//transcription, DNA-templated",GO:0000989//transcription factor binding transcription factor activity;GO:0003682//chromatin binding;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0070888//E-box binding;GO:0003677//DNA binding,-
4763,0,24,1,43,263,45,14,110,87,0,31,0,NF1;neurofibromin 1,GO:0016020//membrane;GO:0030424//axon;GO:0030425//dendrite;GO:0005730//nucleolus;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0048485//sympathetic nervous system development;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0030198//extracellular matrix organization;GO:0007154//cell communication;GO:0007406//negative regulation of neuroblast proliferation;GO:0043473//pigmentation;GO:0001656//metanephros development;GO:0006469//negative regulation of protein kinase activity;GO:0007422//peripheral nervous system development;GO:0048745//smooth muscle tissue development;GO:0000165//MAPK cascade;GO:0030036//actin cytoskeleton organization;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0042060//wound healing;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0048593//camera-type eye morphogenesis;GO:0045762//positive regulation of adenylate cyclase activity;GO:0001952//regulation of cell-matrix adhesion;GO:0014044//Schwann cell development;GO:0030325//adrenal gland development;GO:0022011//myelination in peripheral nervous system;GO:0001938//positive regulation of endothelial cell proliferation;GO:0035021//negative regulation of Rac protein signal transduction;GO:0045765//regulation of angiogenesis;GO:0021915//neural tube development;GO:0001953//negative regulation of cell-matrix adhesion;GO:0032318//regulation of Ras GTPase activity;GO:0001937//negative regulation of endothelial cell proliferation;GO:0043407//negative regulation of MAP kinase activity;GO:0032320//positive regulation of Ras GTPase activity;GO:0001666//response to hypoxia;GO:0043065//positive regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0021510//spinal cord development;GO:0001889//liver development;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0007507//heart development;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0007265//Ras protein signal transduction;GO:0030199//collagen fibril organization;GO:0043525//positive regulation of neuron apoptotic process;GO:0007420//brain development;GO:0030336//negative regulation of cell migration;GO:0016525//negative regulation of angiogenesis;GO:0008542//visual learning;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0001649//osteoblast differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:0043409//negative regulation of MAPK cascade;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0046580//negative regulation of Ras protein signal transduction;GO:0046929//negative regulation of neurotransmitter secretion;GO:0048853//forebrain morphogenesis;GO:0048844//artery morphogenesis;GO:0045124//regulation of bone resorption;GO:0050890//cognition;GO:0021987//cerebral cortex development;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0045671//negative regulation of osteoclast differentiation;GO:0021897//forebrain astrocyte development;GO:0007519//skeletal muscle tissue development",GO:0005515//protein binding;GO:0008429//phosphatidylethanolamine binding;GO:0005099//Ras GTPase activator activity;GO:0031210//phosphatidylcholine binding,K08052//MAPK signaling pathway
477,0,0,0,0,0,23,22,0,57,0,8,0,"ATP1A2;ATPase, Na+/K+ transporting, alpha 2 polypeptide",GO:0005886//plasma membrane;GO:0005768//endosome;GO:0045202//synapse;GO:0030315//T-tubule;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005901//caveola,GO:0034220//ion transmembrane transport;GO:0008217//regulation of blood pressure;GO:0019229//regulation of vasoconstriction;GO:0006942//regulation of striated muscle contraction;GO:0071260//cellular response to mechanical stimulus;GO:0030007//cellular potassium ion homeostasis;GO:0045822//negative regulation of heart contraction;GO:0008344//adult locomotory behavior;GO:0040011//locomotion;GO:0006754//ATP biosynthetic process;GO:0006814//sodium ion transport;GO:0008542//visual learning;GO:0035094//response to nicotine;GO:0002026//regulation of the force of heart contraction;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0086004//regulation of cardiac muscle cell contraction;GO:0006813//potassium ion transport;GO:0055085//transmembrane transport;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0045988//negative regulation of striated muscle contraction;GO:0001504//neurotransmitter uptake;GO:0010107//potassium ion import;GO:0006883//cellular sodium ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006940//regulation of smooth muscle contraction,GO:0005524//ATP binding;GO:0051087//chaperone binding;GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption
4771,40,0,1,6,94,0,32,0,59,116,14,254,NF2;neurofibromin 2 (merlin),GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0031527//filopodium membrane;GO:0032154//cleavage furrow;GO:0016020//membrane;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0005730//nucleolus;GO:0019898//extrinsic component of membrane;GO:0030027//lamellipodium;GO:0045177//apical part of cell;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0048471//perinuclear region of cytoplasm;GO:0030864//cortical actin cytoskeleton;GO:0032587//ruffle membrane,GO:0070306//lens fiber cell differentiation;GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0031647//regulation of protein stability;GO:0030036//actin cytoskeleton organization;GO:0007398//ectoderm development;GO:0008156//negative regulation of DNA replication;GO:0006469//negative regulation of protein kinase activity;GO:0014010//Schwann cell proliferation;GO:0021766//hippocampus development;GO:0045216//cell-cell junction organization;GO:2000177//regulation of neural precursor cell proliferation;GO:0001707//mesoderm formation;GO:0042518//negative regulation of tyrosine phosphorylation of Stat3 protein;GO:0046426//negative regulation of JAK-STAT cascade;GO:0035330//regulation of hippo signaling;GO:0042524//negative regulation of tyrosine phosphorylation of Stat5 protein;GO:0045597//positive regulation of cell differentiation;GO:0022408//negative regulation of cell-cell adhesion;GO:0043409//negative regulation of MAPK cascade;GO:0051496//positive regulation of stress fiber assembly;GO:0001953//negative regulation of cell-matrix adhesion;GO:0042475//odontogenesis of dentin-containing tooth,GO:0005515//protein binding;GO:0003779//actin binding,K05762//Regulation of actin cytoskeleton;K08007//Leukocyte transendothelial migration;Gastric acid secretion;Pathogenic Escherichia coli infection;Regulation of actin cytoskeleton;K05763//Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Measles
4772,0,0,0,1,0,0,23,0,57,10,0,0,"NFATC1;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1",GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,"GO:0006816//calcium ion transport;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0030316//osteoclast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001837//epithelial to mesenchymal transition;GO:0007507//heart development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0000082//G1/S transition of mitotic cell cycle",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0005528//FK506 binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding,K04446//Osteoclast differentiation;T cell receptor signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;VEGF signaling pathway;Axon guidance;HTLV-I infection;B cell receptor signaling pathway
4773,0,0,0,0,0,29,0,48,24,0,7,0,"NFATC2;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2",GO:0044798//nuclear transcription factor complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001816//cytokine production;GO:0016477//cell migration;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0030890//positive regulation of B cell proliferation;GO:0050853//B cell receptor signaling pathway",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K04446//Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Osteoclast differentiation;Wnt signaling pathway;VEGF signaling pathway;Axon guidance;HTLV-I infection;B cell receptor signaling pathway
4774,0,80,21,61,303,20,32,0,69,0,10,361,NFIA;nuclear factor I/A,GO:0005634//nucleus,"GO:0014070//response to organic cyclic compound;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0019079//viral genome replication;GO:0006260//DNA replication;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
4775,0,50,92,86,274,28,0,1,51,0,33,0,"NFATC3;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0006366//transcription from RNA polymerase II promoter;GO:0045333//cellular respiration;GO:0071285//cellular response to lithium ion;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006954//inflammatory response;GO:0071277//cellular response to calcium ion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0051145//smooth muscle cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007507//heart development;GO:0055001//muscle cell development;GO:0001569//patterning of blood vessels,GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K04446//Wnt signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Osteoclast differentiation;VEGF signaling pathway;HTLV-I infection;Axon guidance;B cell receptor signaling pathway
4776,9,0,0,0,0,0,0,0,44,80,12,0,"NFATC4;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4",GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,GO:0007507//heart development;GO:0032760//positive regulation of tumor necrosis factor production;GO:0071285//cellular response to lithium ion;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045333//cellular respiration;GO:0048167//regulation of synaptic plasticity;GO:0034644//cellular response to UV;GO:0001569//patterning of blood vessels;GO:0055001//muscle cell development;GO:0051145//smooth muscle cell differentiation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0006366//transcription from RNA polymerase II promoter,GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0042975//peroxisome proliferator activated receptor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008134//transcription factor binding,K04446//Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Osteoclast differentiation;T cell receptor signaling pathway;Wnt signaling pathway;VEGF signaling pathway;Axon guidance;HTLV-I infection;B cell receptor signaling pathway
4778,0,0,0,0,0,6,40,18,16,0,0,0,"NFE2;nuclear factor, erythroid 2",GO:0015629//actin cytoskeleton;GO:0005730//nucleolus;GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008015//blood circulation;GO:0007599//hemostasis;GO:0007267//cell-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030502//negative regulation of bone mineralization;GO:0006337//nucleosome disassembly;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated;GO:0007596//blood coagulation;GO:0060716//labyrinthine layer blood vessel development",GO:0047485//protein N-terminus binding;GO:0050699//WW domain binding;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
4779,0,0,0,0,29,12,11,48,43,152,0,0,"NFE2L1;nuclear factor, erythroid 2-like 1",GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0006783//heme biosynthetic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation,GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003712//transcription cofactor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
478,0,0,0,0,0,0,34,107,13,0,0,0,"ATP1A3;ATPase, Na+/K+ transporting, alpha 3 polypeptide",GO:0005634//nucleus;GO:0044327//dendritic spine head;GO:0030424//axon;GO:0043209//myelin sheath;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0031982//vesicle;GO:0044326//dendritic spine neck;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0005794//Golgi apparatus,GO:0006754//ATP biosynthetic process;GO:0006883//cellular sodium ion homeostasis;GO:0008542//visual learning;GO:0010107//potassium ion import;GO:0042493//response to drug;GO:0008344//adult locomotory behavior;GO:0030007//cellular potassium ion homeostasis;GO:0007613//memory;GO:0034220//ion transmembrane transport;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0055085//transmembrane transport;GO:0086064//cell communication by electrical coupling involved in cardiac conduction,GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0051087//chaperone binding;GO:0031748//D1 dopamine receptor binding,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
4780,0,0,0,27,98,0,0,90,16,0,0,0,"NFE2L2;nuclear factor, erythroid 2-like 2",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0045995//regulation of embryonic development;GO:0071356//cellular response to tumor necrosis factor;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0071499//cellular response to laminar fluid shear stress;GO:0030194//positive regulation of blood coagulation;GO:0016567//protein ubiquitination;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:2000121//regulation of removal of superoxide radicals;GO:0070301//cellular response to hydrogen peroxide;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0010499//proteasomal ubiquitin-independent protein catabolic process,GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0019904//protein domain specific binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K05638//Protein processing in endoplasmic reticulum
4781,87,130,0,223,720,20,36,32,59,0,0,0,NFIB;nuclear factor I/B,GO:0005730//nucleolus;GO:0044300//cerebellar mossy fiber;GO:0005634//nucleus,GO:0002062//chondrocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000791//negative regulation of mesenchymal cell proliferation involved in lung development;GO:2000795//negative regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0021740//principal sensory nucleus of trigeminal nerve development;GO:0021960//anterior commissure morphogenesis;GO:0060510//Type II pneumocyte differentiation;GO:0060509//Type I pneumocyte differentiation;GO:0006260//DNA replication;GO:0060486//Clara cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0071679//commissural neuron axon guidance;GO:0061141//lung ciliated cell differentiation;GO:0010001//glial cell differentiation;GO:0030902//hindbrain development;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003690//double-stranded DNA binding,-
4782,0,4,35,29,38,0,0,2,37,29,16,0,NFIC;nuclear factor I/C (CCAAT-binding transcription factor),GO:0005730//nucleolus;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding;GO:0001159//core promoter proximal region DNA binding,-
4783,0,0,0,40,41,0,0,0,0,9,7,0,"NFIL3;nuclear factor, interleukin 3 regulated",GO:0005634//nucleus,GO:0010628//positive regulation of gene expression;GO:0007623//circadian rhythm;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071353//cellular response to interleukin-4;GO:0006955//immune response;GO:0006366//transcription from RNA polymerase II promoter,GO:0003714//transcription corepressor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
4784,0,3,1,56,171,0,13,1,38,0,24,0,NFIX;nuclear factor I/X (CCAAT-binding transcription factor),GO:0005634//nucleus,GO:0006260//DNA replication;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021707//cerebellar granule cell differentiation;GO:0048708//astrocyte differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0021680//cerebellar Purkinje cell layer development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
479,50,0,0,0,0,44,100,30,70,9,0,0,"ATP12A;ATPase, H+/K+ transporting, nongastric, alpha polypeptide",GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005889//hydrogen:potassium-exchanging ATPase complex,GO:0055075//potassium ion homeostasis;GO:0055085//transmembrane transport;GO:0006885//regulation of pH;GO:0034220//ion transmembrane transport;GO:0006754//ATP biosynthetic process;GO:0006813//potassium ion transport;GO:1902600//hydrogen ion transmembrane transport,GO:0008900//hydrogen:potassium-exchanging ATPase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,K01544//Oxidative phosphorylation
4790,0,1,0,6,20,0,0,0,66,0,27,1,NFKB1;nuclear factor of kappa light polypeptide gene enhancer in B-cells 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0033256//I-kappaB/NF-kappaB complex;GO:0005730//nucleolus,"GO:0071347//cellular response to interleukin-1;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0010956//negative regulation of calcidiol 1-monooxygenase activity;GO:0006979//response to oxidative stress;GO:0050852//T cell receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0001818//negative regulation of cytokine production;GO:0071222//cellular response to lipopolysaccharide;GO:0046688//response to copper ion;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0071354//cellular response to interleukin-6;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0071316//cellular response to nicotine;GO:0071260//cellular response to mechanical stimulus;GO:0031293//membrane protein intracellular domain proteolysis;GO:0050728//negative regulation of inflammatory response;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0071375//cellular response to peptide hormone stimulus;GO:2000630//positive regulation of miRNA metabolic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0032375//negative regulation of cholesterol transport;GO:0045083//negative regulation of interleukin-12 biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0032269//negative regulation of cellular protein metabolic process;GO:0034166//toll-like receptor 10 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0010884//positive regulation of lipid storage;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway",GO:0000975//regulatory region DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K02580//Amoebiasis;T cell receptor signaling pathway;Chronic myeloid leukemia;Prostate cancer;Tuberculosis;Small cell lung cancer;Salmonella infection;Measles;Adipocytokine signaling pathway;Neurotrophin signaling pathway;Hepatitis C;Cytosolic DNA-sensing pathway;Transcriptional misregulation in cancer;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Acute myeloid leukemia;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Apoptosis;MAPK signaling pathway;Herpes simplex infection;Pertussis;Influenza A;Toll-like receptor signaling pathway;Chemokine signaling pathway;Pathways in cancer;Cocaine addiction;Pancreatic cancer;NF-kappa B signaling pathway;Toxoplasmosis;Leishmaniasis;Osteoclast differentiation;Legionellosis;NOD-like receptor signaling pathway;Shigellosis;HTLV-I infection
4791,0,0,0,10,6,0,17,65,40,0,9,0,NFKB2;nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100),GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002268//follicular dendritic cell differentiation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0038061//NIK/NF-kappaB signaling;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0030198//extracellular matrix organization;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0002467//germinal center formation;GO:0002756//MyD88-independent toll-like receptor signaling pathway",GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K04469//Epstein-Barr virus infection;Legionellosis;NF-kappa B signaling pathway;HTLV-I infection;Pathways in cancer;Osteoclast differentiation;MAPK signaling pathway
4792,0,0,0,0,53,0,0,0,25,0,0,0,"NFKBIA;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0033256//I-kappaB/NF-kappaB complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0032270//positive regulation of cellular protein metabolic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043330//response to exogenous dsRNA;GO:0070417//cellular response to cold;GO:0034142//toll-like receptor 4 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034146//toll-like receptor 5 signaling pathway;GO:0042127//regulation of cell proliferation;GO:0016032//viral process;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0032495//response to muramyl dipeptide;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0070427//nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0045638//negative regulation of myeloid cell differentiation;GO:0010888//negative regulation of lipid storage;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0010875//positive regulation of cholesterol efflux;GO:0043392//negative regulation of DNA binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000060//protein import into nucleus, translocation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006915//apoptotic process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045746//negative regulation of Notch signaling pathway",GO:0008139//nuclear localization sequence binding;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0051059//NF-kappaB binding;GO:0032403//protein complex binding;GO:0019899//enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding,K04734//Legionellosis;Shigellosis;NOD-like receptor signaling pathway;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);HTLV-I infection;Measles;Osteoclast differentiation;Toxoplasmosis;Leishmaniasis;Adipocytokine signaling pathway;Cytosolic DNA-sensing pathway;Hepatitis C;Neurotrophin signaling pathway;Prostate cancer;Toll-like receptor signaling pathway;Small cell lung cancer;Influenza A;Chemokine signaling pathway;Pathways in cancer;NF-kappa B signaling pathway;RIG-I-like receptor signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;Herpes simplex infection;T cell receptor signaling pathway;Apoptosis;Chronic myeloid leukemia
4793,0,0,106,0,0,0,0,0,15,0,12,0,"NFKBIB;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta",GO:0005634//nucleus;GO:0005829//cytosol,"GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction",GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity,K02581//Chemokine signaling pathway;Influenza A;B cell receptor signaling pathway;NOD-like receptor signaling pathway;Shigellosis;Neurotrophin signaling pathway;Cytosolic DNA-sensing pathway;Toxoplasmosis;Leishmaniasis;T cell receptor signaling pathway;Adipocytokine signaling pathway;Herpes simplex infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Measles
4794,2,1,0,0,1,16,0,0,7,0,0,0,"NFKBIE;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon",GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0005829//cytosol,GO:0042942//D-serine transport;GO:0042994//cytoplasmic sequestering of transcription factor,GO:0005515//protein binding,K05872//Adipocytokine signaling pathway;T cell receptor signaling pathway;Neurotrophin signaling pathway;B cell receptor signaling pathway;Epstein-Barr virus infection
4796,113,3,39,1,18,18,0,75,31,1,96,948,"TONSL;tonsoku-like, DNA repair protein",GO:0043596//nuclear replication fork;GO:0005662//DNA replication factor A complex;GO:0005730//nucleolus;GO:0035101//FACT complex;GO:0042555//MCM complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0042994//cytoplasmic sequestering of transcription factor;GO:2001141//regulation of RNA biosynthetic process;GO:0000724//double-strand break repair via homologous recombination;GO:0031297//replication fork processing,GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042393//histone binding,-
4798,87,0,0,0,0,0,0,0,35,0,8,264,NFRKB;nuclear factor related to kappaB binding protein,GO:0005730//nucleolus;GO:0031011//Ino80 complex;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006310//DNA recombination",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0002020//protease binding,-
4799,104,29,0,17,68,18,0,9,56,89,0,1,"NFX1;nuclear transcription factor, X-box binding 1",GO:0005634//nucleus,GO:0006954//inflammatory response;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
48,1,0,0,50,99,0,25,2,36,0,0,0,"ACO1;aconitase 1, soluble",GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion,GO:0006101//citrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0050892//intestinal absorption;GO:0010040//response to iron(II) ion;GO:0006879//cellular iron ion homeostasis;GO:0006417//regulation of translation;GO:0009791//post-embryonic development,"GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030350//iron-responsive element binding;GO:0003994//aconitate hydratase activity;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003723//RNA binding","K01681//Glyoxylate and dicarboxylate metabolism;Microbial metabolism in diverse environments;Phenylalanine, tyrosine and tryptophan biosynthesis;Carbon fixation pathways in prokaryotes;Citrate cycle (TCA cycle);Metabolic pathways;Biosynthesis of secondary metabolites"
480,0,0,0,5,0,0,0,32,27,0,15,0,"ATP1A4;ATPase, Na+/K+ transporting, alpha 4 polypeptide",GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006754//ATP biosynthetic process;GO:0006814//sodium ion transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0030641//regulation of cellular pH;GO:0055085//transmembrane transport;GO:0009566//fertilization;GO:0042391//regulation of membrane potential;GO:0007283//spermatogenesis;GO:0030317//sperm motility;GO:0035725//sodium ion transmembrane transport,GO:0005524//ATP binding;GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0046872//metal ion binding,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption
4800,0,31,0,18,32,22,92,0,43,0,0,158,"NFYA;nuclear transcription factor Y, alpha",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016602//CCAAT-binding factor complex,"GO:2000036//regulation of stem cell maintenance;GO:2000648//positive regulation of stem cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0003677//DNA binding,K08064//Tuberculosis;Antigen processing and presentation
4801,8,38,14,52,27,10,0,0,14,0,0,0,"NFYB;nuclear transcription factor Y, beta",GO:0016602//CCAAT-binding factor complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0006351//transcription, DNA-templated",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0070491//repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding,K08065//Tuberculosis;Antigen processing and presentation;HTLV-I infection
4802,0,1,0,17,45,0,0,115,0,287,9,0,"NFYC;nuclear transcription factor Y, gamma",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016602//CCAAT-binding factor complex;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0006457//protein folding;GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity,K08066//Antigen processing and presentation;Tuberculosis
4803,0,0,0,0,0,11,0,0,0,0,0,0,NGF;nerve growth factor (beta polypeptide),GO:0005796//Golgi lumen;GO:0005768//endosome;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0007623//circadian rhythm;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035094//response to nicotine;GO:0007613//memory;GO:0045666//positive regulation of neuron differentiation;GO:0008344//adult locomotory behavior;GO:0043524//negative regulation of neuron apoptotic process;GO:0019233//sensory perception of pain;GO:0045786//negative regulation of cell cycle;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045773//positive regulation of axon extension;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0050770//regulation of axonogenesis;GO:0051602//response to electrical stimulus;GO:0000186//activation of MAPKK activity;GO:2000648//positive regulation of stem cell proliferation;GO:0007265//Ras protein signal transduction;GO:0032455//nerve growth factor processing;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0010193//response to ozone;GO:0043434//response to peptide hormone;GO:0043065//positive regulation of apoptotic process;GO:0009314//response to radiation;GO:0031954//positive regulation of protein autophosphorylation;GO:0009612//response to mechanical stimulus;GO:0014042//positive regulation of neuron maturation;GO:0010976//positive regulation of neuron projection development;GO:0050772//positive regulation of axonogenesis;GO:0051388//positive regulation of neurotrophin TRK receptor signaling pathway;GO:0006954//inflammatory response;GO:0007202//activation of phospholipase C activity;GO:0051402//neuron apoptotic process;GO:0032496//response to lipopolysaccharide;GO:0007422//peripheral nervous system development;GO:0048812//neuron projection morphogenesis;GO:0051384//response to glucocorticoid;GO:0042493//response to drug;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0046928//regulation of neurotransmitter secretion,GO:0005163//nerve growth factor receptor binding;GO:0005057//receptor signaling protein activity;GO:0008083//growth factor activity,K02582//Apoptosis;MAPK signaling pathway;Neurotrophin signaling pathway
4804,0,0,0,0,0,0,0,0,20,0,0,0,NGFR;nerve growth factor receptor,GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0097481//neuronal postsynaptic density,GO:0045786//negative regulation of cell cycle;GO:0050772//positive regulation of axonogenesis;GO:0006886//intracellular protein transport;GO:0021675//nerve development;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0031293//membrane protein intracellular domain proteolysis;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031069//hair follicle morphogenesis;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042593//glucose homeostasis;GO:0042488//positive regulation of odontogenesis of dentin-containing tooth;GO:2001273//regulation of glucose import in response to insulin stimulus;GO:0032922//circadian regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0050771//negative regulation of axonogenesis;GO:0007411//axon guidance;GO:0050770//regulation of axonogenesis;GO:0007417//central nervous system development;GO:0048146//positive regulation of fibroblast proliferation;GO:0051799//negative regulation of hair follicle development;GO:0016048//detection of temperature stimulus,GO:0005035//death receptor activity;GO:0048406//nerve growth factor binding;GO:0005515//protein binding;GO:0017137//Rab GTPase binding;GO:0004872//receptor activity;GO:0004871//signal transducer activity;GO:0031625//ubiquitin protein ligase binding;GO:0004888//transmembrane signaling receptor activity,K02583//Transcriptional misregulation in cancer;Neurotrophin signaling pathway;Cytokine-cytokine receptor interaction
4807,3,0,0,0,0,0,19,50,47,0,0,0,NHLH1;nescient helix loop helix 1,GO:0005634//nucleus,"GO:0007417//central nervous system development;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
4808,0,0,0,0,0,0,0,0,0,0,7,0,NHLH2;nescient helix loop helix 2,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0042698//ovulation cycle;GO:0030154//cell differentiation;GO:0007417//central nervous system development;GO:0007617//mating behavior",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0046983//protein dimerization activity,-
4809,0,1,0,19,115,0,0,0,20,0,0,0,NHP2L1;NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae),GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0031428//box C/D snoRNP complex;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0042254//ribosome biogenesis;GO:0000398//mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0030515//snoRNA binding,K12845//Ribosome biogenesis in eukaryotes;Spliceosome
481,0,0,0,0,0,0,0,0,1,0,0,0,"ATP1B1;ATPase, Na+/K+ transporting, beta 1 polypeptide",GO:0005901//caveola;GO:0016323//basolateral plasma membrane;GO:0042383//sarcolemma;GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0014704//intercalated disc,GO:0055085//transmembrane transport;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055119//relaxation of cardiac muscle;GO:0050821//protein stabilization;GO:0072659//protein localization to plasma membrane;GO:0086009//membrane repolarization;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0032781//positive regulation of ATPase activity;GO:0010107//potassium ion import;GO:0006883//cellular sodium ion homeostasis;GO:0006874//cellular calcium ion homeostasis;GO:0060048//cardiac muscle contraction;GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0010468//regulation of gene expression;GO:0034220//ion transmembrane transport;GO:0001666//response to hypoxia;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:0050900//leukocyte migration;GO:0030007//cellular potassium ion homeostasis,GO:0023026//MHC class II protein complex binding;GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0051117//ATPase binding;GO:0005391//sodium:potassium-exchanging ATPase activity,K01540//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
4810,0,0,0,8,0,0,0,0,88,2,22,0,NHS;Nance-Horan syndrome (congenital cataracts and dental anomalies),GO:0005925//focal adhesion;GO:0005923//tight junction;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:0030154//cell differentiation;GO:0002088//lens development in camera-type eye,-,-
4811,194,0,0,0,0,49,0,48,66,0,0,1,NID1;nidogen 1,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005605//basal lamina;GO:0005604//basement membrane;GO:0031012//extracellular matrix;GO:0071944//cell periphery,GO:0071711//basement membrane organization;GO:0010811//positive regulation of cell-substrate adhesion;GO:0032836//glomerular basement membrane development;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0007160//cell-matrix adhesion,GO:0043237//laminin-1 binding;GO:0005509//calcium ion binding;GO:0043394//proteoglycan binding;GO:0043236//laminin binding;GO:0005518//collagen binding,-
4814,0,0,0,0,0,0,29,0,0,113,0,0,NINJ1;ninjurin 1,GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0042246//tissue regeneration;GO:1990384//hyaloid vascular plexus regression;GO:0001954//positive regulation of cell-matrix adhesion,-,-
4815,0,0,0,10,0,0,0,0,19,0,0,0,NINJ2;ninjurin 2,GO:0005887//integral component of plasma membrane,GO:0007399//nervous system development;GO:0042246//tissue regeneration;GO:0007158//neuron cell-cell adhesion,-,-
4817,1,232,166,288,337,16,0,327,19,0,663,0,NIT1;nitrilase 1,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0006807//nitrogen compound metabolic process,GO:0000257//nitrilase activity,-
4818,0,0,0,0,0,0,0,0,12,1,0,0,NKG7;natural killer cell granule protein 7,GO:0005887//integral component of plasma membrane,-,-,-
482,0,0,0,0,0,18,0,0,6,0,8,0,"ATP1B2;ATPase, Na+/K+ transporting, beta 2 polypeptide",GO:0005890//sodium:potassium-exchanging ATPase complex;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane,GO:0050900//leukocyte migration;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:0006883//cellular sodium ion homeostasis;GO:0010107//potassium ion import;GO:0032781//positive regulation of ATPase activity;GO:0030007//cellular potassium ion homeostasis;GO:0050821//protein stabilization;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055085//transmembrane transport;GO:0007155//cell adhesion;GO:0086009//membrane repolarization;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007596//blood coagulation,GO:0005515//protein binding;GO:0001671//ATPase activator activity;GO:0051117//ATPase binding;GO:0005391//sodium:potassium-exchanging ATPase activity,K01540//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
4820,0,13,0,15,121,0,18,0,45,0,0,0,NKTR;natural killer cell triggering receptor,GO:0016020//membrane,GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization,GO:0016018//cyclosporin A binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
4821,104,0,0,0,0,5,0,1,0,0,0,0,NKX2-2;NK2 homeobox 2,GO:0005654//nucleoplasm,"GO:0045666//positive regulation of neuron differentiation;GO:0032570//response to progesterone;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0031018//endocrine pancreas development;GO:0014003//oligodendrocyte development;GO:0007224//smoothened signaling pathway;GO:0003323//type B pancreatic cell development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060580//ventral spinal cord interneuron fate determination;GO:0048565//digestive tract development;GO:0003329//pancreatic PP cell fate commitment;GO:0009749//response to glucose;GO:0003327//type B pancreatic cell fate commitment;GO:0048665//neuron fate specification;GO:0021530//spinal cord oligodendrocyte cell fate specification;GO:0048708//astrocyte differentiation;GO:0021554//optic nerve development;GO:0007420//brain development;GO:0006351//transcription, DNA-templated;GO:0021522//spinal cord motor neuron differentiation;GO:0003326//pancreatic A cell fate commitment;GO:0045665//negative regulation of neuron differentiation",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003682//chromatin binding;GO:0001159//core promoter proximal region DNA binding;GO:0003713//transcription coactivator activity,K08029//Maturity onset diabetes of the young
4824,0,443,4,227,751,0,1,155,1,0,21,0,NKX3-1;NK3 homeobox 1,GO:0005622//intracellular;GO:0005634//nucleus,"GO:0051781//positive regulation of cell division;GO:0071356//cellular response to tumor necrosis factor;GO:0043401//steroid hormone mediated signaling pathway;GO:0071347//cellular response to interleukin-1;GO:0071899//negative regulation of estrogen receptor binding;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:2001022//positive regulation of response to DNA damage stimulus;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0008584//male gonad development;GO:0010629//negative regulation of gene expression;GO:0045931//positive regulation of mitotic cell cycle;GO:0043491//protein kinase B signaling;GO:0008284//positive regulation of cell proliferation;GO:0045930//negative regulation of mitotic cell cycle;GO:0060442//branching involved in prostate gland morphogenesis;GO:0035907//dorsal aorta development;GO:0071850//mitotic cell cycle arrest;GO:0007507//heart development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010942//positive regulation of cell death;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:2000836//positive regulation of androgen secretion;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007431//salivary gland development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0045860//positive regulation of protein kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060037//pharyngeal system development;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001656//metanephros development;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0006355//regulation of transcription, DNA-templated;GO:0001756//somitogenesis;GO:0071456//cellular response to hypoxia;GO:0033574//response to testosterone;GO:0035690//cellular response to drug;GO:0071383//cellular response to steroid hormone stimulus;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0030295//protein kinase activator activity;GO:0004882//androgen receptor activity;GO:0030331//estrogen receptor binding;GO:0030284//estrogen receptor activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0001047//core promoter binding;GO:0097162//MADS box domain binding;GO:0043621//protein self-association;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding,K09348//Prostate cancer;Pathways in cancer
4825,0,0,0,0,0,0,0,67,0,0,0,0,NKX6-1;NK6 homeobox 1,GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0045686//negative regulation of glial cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045666//positive regulation of neuron differentiation;GO:0035094//response to nicotine;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0048709//oligodendrocyte differentiation;GO:0032024//positive regulation of insulin secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071375//cellular response to peptide hormone stimulus;GO:0071345//cellular response to cytokine stimulus;GO:0031018//endocrine pancreas development;GO:0007224//smoothened signaling pathway;GO:2001222//regulation of neuron migration;GO:0072560//type B pancreatic cell maturation;GO:0031016//pancreas development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009887//organ morphogenesis;GO:0021912//regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification;GO:0008283//cell proliferation;GO:0045687//positive regulation of glial cell differentiation;GO:2000078//positive regulation of type B pancreatic cell development;GO:0030516//regulation of axon extension;GO:0051594//detection of glucose;GO:0042493//response to drug,GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding,K08030//Maturity onset diabetes of the young
4826,0,25,0,7,16,0,0,0,0,0,0,0,NNAT;neuronatin,GO:0005737//cytoplasm,GO:0007420//brain development;GO:0009249//protein lipoylation;GO:0030182//neuron differentiation;GO:0032880//regulation of protein localization;GO:0006810//transport;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose,-,K00850//Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Pentose phosphate pathway;Galactose metabolism;Metabolic pathways;Fructose and mannose metabolism
4828,0,0,0,0,0,0,0,0,1,0,0,0,NMB;neuromedin B,GO:0005576//extracellular region;GO:0043005//neuron projection,GO:0046888//negative regulation of hormone secretion;GO:0007218//neuropeptide signaling pathway;GO:0046887//positive regulation of hormone secretion;GO:0050482//arachidonic acid secretion;GO:0007165//signal transduction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007267//cell-cell signaling;GO:0042593//glucose homeostasis;GO:0008284//positive regulation of cell proliferation,GO:0005179//hormone activity,-
4829,0,0,0,0,0,0,0,0,17,0,0,0,NMBR;neuromedin B receptor,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0031989//bombesin receptor signaling pathway,GO:0004946//bombesin receptor activity,K04168//Neuroactive ligand-receptor interaction
483,0,1,0,7,0,13,15,0,0,32,0,0,"ATP1B3;ATPase, Na+/K+ transporting, beta 3 polypeptide",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0005901//caveola;GO:0005890//sodium:potassium-exchanging ATPase complex,GO:0030007//cellular potassium ion homeostasis;GO:0010107//potassium ion import;GO:0032781//positive regulation of ATPase activity;GO:0006883//cellular sodium ion homeostasis;GO:1901018//positive regulation of potassium ion transmembrane transporter activity;GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0006810//transport;GO:0072659//protein localization to plasma membrane;GO:0034220//ion transmembrane transport;GO:0086009//membrane repolarization;GO:0055085//transmembrane transport;GO:0050821//protein stabilization,GO:0051117//ATPase binding;GO:0005391//sodium:potassium-exchanging ATPase activity;GO:0001671//ATPase activator activity,K01540//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
4830,0,0,0,0,29,0,3,0,0,0,0,0,NME1;NME/NM23 nucleoside diphosphate kinase 1,GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0006165//nucleoside diphosphate phosphorylation;GO:0043388//positive regulation of DNA binding;GO:0033574//response to testosterone;GO:0035690//cellular response to drug;GO:0008285//negative regulation of cell proliferation;GO:0006241//CTP biosynthetic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0015949//nucleobase-containing small molecule interconversion;GO:0010629//negative regulation of gene expression;GO:0014075//response to amine;GO:0002762//negative regulation of myeloid leukocyte differentiation;GO:0021766//hippocampus development;GO:0044281//small molecule metabolic process;GO:0006897//endocytosis;GO:0006228//UTP biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0071398//cellular response to fatty acid;GO:0006183//GTP biosynthetic process;GO:0051591//response to cAMP;GO:0042981//regulation of apoptotic process;GO:0007595//lactation;GO:0006308//DNA catabolic process;GO:0010976//positive regulation of neuron projection development,GO:0000287//magnesium ion binding;GO:0019215//intermediate filament binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005525//GTP binding;GO:0043024//ribosomal small subunit binding;GO:0043015//gamma-tubulin binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0003697//single-stranded DNA binding;GO:0019901//protein kinase binding;GO:0004536//deoxyribonuclease activity,K00940//Bacterial invasion of epithelial cells;Metabolic pathways;Purine metabolism;Shigellosis;Nitrogen metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
4831,0,1,0,0,1,0,0,0,4,0,0,0,NME2;NME/NM23 nucleoside diphosphate kinase 2,GO:0070062//extracellular vesicular exosome;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0071944//cell periphery;GO:0005634//nucleus,"GO:0007229//integrin-mediated signaling pathway;GO:0045682//regulation of epidermis development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0018106//peptidyl-histidine phosphorylation;GO:0006183//GTP biosynthetic process;GO:0007155//cell adhesion;GO:0006228//UTP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0015949//nucleobase-containing small molecule interconversion;GO:0045618//positive regulation of keratinocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006241//CTP biosynthetic process;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0006165//nucleoside diphosphate phosphorylation",GO:0004550//nucleoside diphosphate kinase activity;GO:0004673//protein histidine kinase activity;GO:0005524//ATP binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,K00940//Nitrogen metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Shigellosis;Purine metabolism;Bacterial invasion of epithelial cells;Metabolic pathways
4832,0,0,0,0,0,6,0,1,0,0,0,0,NME3;NME/NM23 nucleoside diphosphate kinase 3,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0006228//UTP biosynthetic process;GO:0006915//apoptotic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006183//GTP biosynthetic process;GO:0006241//CTP biosynthetic process,GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0046872//metal ion binding,K00940//Metabolic pathways;Bacterial invasion of epithelial cells;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Nitrogen metabolism;Shigellosis;Purine metabolism
4833,0,48,48,15,30,0,35,0,6,0,11,0,NME4;NME/NM23 nucleoside diphosphate kinase 4,GO:0005739//mitochondrion;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane,GO:0006241//CTP biosynthetic process;GO:0006183//GTP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0009116//nucleoside metabolic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006228//UTP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding;GO:0032403//protein complex binding,K12485//Endocytosis;K00940//Metabolic pathways;Bacterial invasion of epithelial cells;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Nitrogen metabolism;Shigellosis;Purine metabolism
4835,0,0,35,0,77,0,21,0,26,0,79,0,"NQO2;NAD(P)H dehydrogenase, quinone 2",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:0007613//memory,GO:0008753//NADPH dehydrogenase (quinone) activity;GO:0009055//electron carrier activity;GO:0046872//metal ion binding;GO:0001512//dihydronicotinamide riboside quinone reductase activity,-
4836,0,2,0,1,21,0,0,0,17,0,0,0,NMT1;N-myristoyltransferase 1,GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm,"GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0001701//in utero embryonic development;GO:0006499//N-terminal protein myristoylation;GO:0016032//viral process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0009249//protein lipoylation;GO:0006915//apoptotic process;GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway",GO:0003824//catalytic activity;GO:0004379//glycylpeptide N-tetradecanoyltransferase activity,-
4838,84,0,0,0,0,0,0,0,30,0,11,0,NODAL;nodal growth differentiation factor,GO:0005615//extracellular space,GO:0001947//heart looping;GO:0002085//inhibition of neuroepithelial cell differentiation;GO:0001842//neural fold formation;GO:0009880//embryonic pattern specification;GO:0035987//endodermal cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045766//positive regulation of angiogenesis;GO:0060395//SMAD protein signal transduction;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060137//maternal process involved in parturition;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0060460//left lung morphogenesis;GO:0033505//floor plate morphogenesis;GO:0048546//digestive tract morphogenesis;GO:1900224//positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010085//polarity specification of proximal/distal axis;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007420//brain development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0001893//maternal placenta development;GO:0001890//placenta development;GO:0048382//mesendoderm development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0001831//trophectodermal cellular morphogenesis;GO:0060802//epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:1901383//negative regulation of chorionic trophoblast cell proliferation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0001889//liver development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0048327//axial mesodermal cell fate specification;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0060136//embryonic process involved in female pregnancy;GO:0019827//stem cell maintenance;GO:0040007//growth;GO:2000036//regulation of stem cell maintenance;GO:0022409//positive regulation of cell-cell adhesion;GO:0010470//regulation of gastrulation;GO:0048859//formation of anatomical boundary;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0001944//vasculature development;GO:0090010//transforming growth factor beta receptor signaling pathway involved in primitive streak formation;GO:1901164//negative regulation of trophoblast cell migration;GO:0042074//cell migration involved in gastrulation;GO:0001892//embryonic placenta development,GO:0016015//morphogen activity;GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0048018//receptor agonist activity;GO:0070698//type I activin receptor binding,K04666//TGF-beta signaling pathway
4839,0,0,0,0,8,0,34,0,1,0,0,0,NOP2;NOP2 nucleolar protein,GO:0005730//nucleolus,GO:0032259//methylation;GO:0008284//positive regulation of cell proliferation;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity,-
4841,0,83,1,51,266,7,2,0,49,54,0,0,"NONO;non-POU domain containing, octamer-binding",GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0042382//paraspeckles;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0016020//membrane,"GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0008380//RNA splicing;GO:0007623//circadian rhythm;GO:0006397//mRNA processing",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0042802//identical protein binding;GO:0001047//core promoter binding,-
4842,0,0,0,0,0,56,36,37,111,0,30,685,NOS1;nitric oxide synthase 1 (neuronal),GO:0001917//photoreceptor inner segment;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043197//dendritic spine;GO:0045121//membrane raft;GO:0045202//synapse;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0042383//sarcolemma;GO:0016529//sarcoplasmic reticulum,"GO:0055114//oxidation-reduction process;GO:0007520//myoblast fusion;GO:0007596//blood coagulation;GO:0031284//positive regulation of guanylate cyclase activity;GO:0001666//response to hypoxia;GO:0033555//multicellular organismal response to stress;GO:0007263//nitric oxide mediated signal transduction;GO:0071363//cellular response to growth factor stimulus;GO:0006941//striated muscle contraction;GO:0051926//negative regulation of calcium ion transport;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0051701//interaction with host;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006527//arginine catabolic process;GO:0090382//phagosome maturation;GO:0045909//positive regulation of vasodilation;GO:0051612//negative regulation of serotonin uptake;GO:0045776//negative regulation of blood pressure;GO:0002028//regulation of sodium ion transport;GO:0035066//positive regulation of histone acetylation;GO:1902307//positive regulation of sodium ion transmembrane transport;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0006809//nitric oxide biosynthetic process;GO:0043267//negative regulation of potassium ion transport;GO:0009408//response to heat;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042738//exogenous drug catabolic process;GO:0055117//regulation of cardiac muscle contraction;GO:0051346//negative regulation of hydrolase activity;GO:0042136//neurotransmitter biosynthetic process",GO:0050661//NADP binding;GO:0010181//FMN binding;GO:0005516//calmodulin binding;GO:0005506//iron ion binding;GO:0017080//sodium channel regulator activity;GO:0097110//scaffold protein binding;GO:0034617//tetrahydrobiopterin binding;GO:0044325//ion channel binding;GO:0016491//oxidoreductase activity;GO:0034618//arginine binding;GO:0020037//heme binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0046870//cadmium ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0005515//protein binding;GO:0004517//nitric-oxide synthase activity,K13240//Phagosome;Long-term depression;Salivary secretion;Calcium signaling pathway;Metabolic pathways;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;Arginine and proline metabolism
4843,0,0,0,0,0,29,22,62,51,271,6,1,"NOS2;nitric oxide synthase 2, inducible",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005777//peroxisome;GO:0005622//intracellular;GO:0030863//cortical cytoskeleton;GO:0005829//cytosol,GO:0010629//negative regulation of gene expression;GO:0051712//positive regulation of killing of cells of other organism;GO:0050829//defense response to Gram-negative bacterium;GO:0002227//innate immune response in mucosa;GO:0050796//regulation of insulin secretion;GO:0006809//nitric oxide biosynthetic process;GO:0043457//regulation of cellular respiration;GO:0042742//defense response to bacterium;GO:0006801//superoxide metabolic process;GO:0090382//phagosome maturation;GO:0051701//interaction with host;GO:0006954//inflammatory response;GO:0018119//peptidyl-cysteine S-nitrosylation;GO:0006527//arginine catabolic process;GO:0042127//regulation of cell proliferation;GO:0009617//response to bacterium;GO:0045776//negative regulation of blood pressure;GO:0071346//cellular response to interferon-gamma;GO:0045909//positive regulation of vasodilation;GO:0071222//cellular response to lipopolysaccharide;GO:0001666//response to hypoxia;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0042177//negative regulation of protein catabolic process;GO:0001912//positive regulation of leukocyte mediated cytotoxicity;GO:0007623//circadian rhythm;GO:0007263//nitric oxide mediated signal transduction,GO:0005506//iron ion binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0050661//NADP binding;GO:0020037//heme binding;GO:0005516//calmodulin binding;GO:0010181//FMN binding;GO:0004517//nitric-oxide synthase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0034618//arginine binding;GO:0005102//receptor binding;GO:0050660//flavin adenine dinucleotide binding;GO:0034617//tetrahydrobiopterin binding,K13241//Arginine and proline metabolism;Amoebiasis;Toxoplasmosis;Leishmaniasis;Metabolic pathways;Tuberculosis;Pertussis;Calcium signaling pathway;Peroxisome;Small cell lung cancer;Chagas disease (American trypanosomiasis);Pathways in cancer;Salmonella infection
4846,61,0,0,0,21,36,0,9,53,0,16,0,NOS3;nitric oxide synthase 3 (endothelial cell),GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0005634//nucleus;GO:0005829//cytosol;GO:0030666//endocytic vesicle membrane,GO:0045909//positive regulation of vasodilation;GO:0045776//negative regulation of blood pressure;GO:0003100//regulation of systemic arterial blood pressure by endothelin;GO:0043542//endothelial cell migration;GO:0006527//arginine catabolic process;GO:0090382//phagosome maturation;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0030324//lung development;GO:0055114//oxidation-reduction process;GO:0001974//blood vessel remodeling;GO:0044281//small molecule metabolic process;GO:0051346//negative regulation of hydrolase activity;GO:0045766//positive regulation of angiogenesis;GO:0001701//in utero embryonic development;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0034405//response to fluid shear stress;GO:0014740//negative regulation of muscle hyperplasia;GO:0009408//response to heat;GO:0007005//mitochondrion organization;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0001542//ovulation from ovarian follicle;GO:0051701//interaction with host;GO:0051926//negative regulation of calcium ion transport;GO:0007263//nitric oxide mediated signal transduction;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007596//blood coagulation;GO:0050999//regulation of nitric-oxide synthase activity;GO:0001525//angiogenesis;GO:0010544//negative regulation of platelet activation;GO:0008285//negative regulation of cell proliferation;GO:0014806//smooth muscle hyperplasia;GO:0046209//nitric oxide metabolic process;GO:0043267//negative regulation of potassium ion transport;GO:0003057//regulation of the force of heart contraction by chemical signal;GO:0002028//regulation of sodium ion transport;GO:0006809//nitric oxide biosynthetic process,GO:0034617//tetrahydrobiopterin binding;GO:0046870//cadmium ion binding;GO:0050660//flavin adenine dinucleotide binding;GO:0034618//arginine binding;GO:0005515//protein binding;GO:0004517//nitric-oxide synthase activity;GO:0010181//FMN binding;GO:0005516//calmodulin binding;GO:0020037//heme binding;GO:0050661//NADP binding;GO:0003785//actin monomer binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0005506//iron ion binding,K13242//Calcium signaling pathway;Arginine and proline metabolism;VEGF signaling pathway;Metabolic pathways
4848,0,28,0,27,25,0,22,1,2,78,29,0,"CNOT2;CCR4-NOT transcription complex, subunit 2",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex;GO:0016020//membrane;GO:0005829//cytosol,"GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006417//regulation of translation;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:2000036//regulation of stem cell maintenance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010606//positive regulation of cytoplasmic mRNA processing body assembly;GO:0016070//RNA metabolic process;GO:0001829//trophectodermal cell differentiation;GO:0016071//mRNA metabolic process;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic",GO:0004535//poly(A)-specific ribonuclease activity;GO:0001226//RNA polymerase II transcription corepressor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,K12605//RNA degradation
4849,0,0,0,0,25,0,66,202,26,0,7,0,"CNOT3;CCR4-NOT transcription complex, subunit 3",GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex;GO:0005829//cytosol,"GO:0006351//transcription, DNA-templated;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006417//regulation of translation;GO:2000036//regulation of stem cell maintenance;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0001829//trophectodermal cell differentiation;GO:0016071//mRNA metabolic process",GO:0005515//protein binding,K12580//RNA degradation
4850,0,0,1,0,21,57,72,0,89,0,13,0,"CNOT4;CCR4-NOT transcription complex, subunit 4",GO:0005829//cytosol;GO:0005634//nucleus;GO:0030014//CCR4-NOT complex,"GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0051865//protein autoubiquitination;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,K10643//RNA degradation
4851,0,0,0,0,0,13,39,15,37,7,11,0,NOTCH1;notch 1,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0002193//MAML1-RBP-Jkappa- ICN1 complex;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0043235//receptor complex;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,"GO:0003180//aortic valve morphogenesis;GO:0060956//endocardial cell differentiation;GO:0003181//atrioventricular valve morphogenesis;GO:0003219//cardiac right ventricle formation;GO:0032495//response to muramyl dipeptide;GO:0003214//cardiac left ventricle morphogenesis;GO:0072144//glomerular mesangial cell development;GO:0035914//skeletal muscle cell differentiation;GO:0002040//sprouting angiogenesis;GO:0003157//endocardium development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0008284//positive regulation of cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0060979//vasculogenesis involved in coronary vascular morphogenesis;GO:0001889//liver development;GO:0035116//embryonic hindlimb morphogenesis;GO:0061384//heart trabecula morphogenesis;GO:0014031//mesenchymal cell development;GO:2000811//negative regulation of anoikis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0006955//immune response;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0042640//anagen;GO:0003192//mitral valve formation;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0003208//cardiac ventricle morphogenesis;GO:0010001//glial cell differentiation;GO:0014807//regulation of somitogenesis;GO:0030514//negative regulation of BMP signaling pathway;GO:0060842//arterial endothelial cell differentiation;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0007219//Notch signaling pathway;GO:0060740//prostate gland epithelium morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035148//tube formation;GO:0045668//negative regulation of osteoblast differentiation;GO:0006959//humoral immune response;GO:0060768//regulation of epithelial cell proliferation involved in prostate gland development;GO:0072017//distal tubule development;GO:0010812//negative regulation of cell-substrate adhesion;GO:0003270//Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation;GO:0003273//cell migration involved in endocardial cushion formation;GO:0003344//pericardium morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:2001027//negative regulation of endothelial cell chemotaxis;GO:0001701//in utero embryonic development;GO:0045662//negative regulation of myoblast differentiation;GO:0060411//cardiac septum morphogenesis;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0001947//heart looping;GO:0007220//Notch receptor processing;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0046427//positive regulation of JAK-STAT cascade;GO:0030900//forebrain development;GO:0007492//endoderm development;GO:0003160//endocardium morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0048103//somatic stem cell division;GO:0030513//positive regulation of BMP signaling pathway;GO:0060843//venous endothelial cell differentiation;GO:0060038//cardiac muscle cell proliferation;GO:0003241//growth involved in heart morphogenesis;GO:2000974//negative regulation of pro-B cell differentiation;GO:0007368//determination of left/right symmetry;GO:0007386//compartment pattern specification;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0072044//collecting duct development;GO:0043086//negative regulation of catalytic activity;GO:0060948//cardiac vascular smooth muscle cell development;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0009912//auditory receptor cell fate commitment;GO:0070986//left/right axis specification;GO:0072602//interleukin-4 secretion;GO:0060271//cilium morphogenesis;GO:0045618//positive regulation of keratinocyte differentiation;GO:0010832//negative regulation of myotube differentiation;GO:1901201//regulation of extracellular matrix assembly;GO:2000737//negative regulation of stem cell differentiation;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0061314//Notch signaling involved in heart development;GO:0007507//heart development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0003184//pulmonary valve morphogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0002437//inflammatory response to antigenic stimulus;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0003207//cardiac chamber formation;GO:0097150//neuronal stem cell maintenance;GO:0050679//positive regulation of epithelial cell proliferation;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0021915//neural tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003169//coronary vein morphogenesis;GO:0003213//cardiac right atrium morphogenesis;GO:0030216//keratinocyte differentiation;GO:0050768//negative regulation of neurogenesis;GO:0030324//lung development;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:0048711//positive regulation of astrocyte differentiation;GO:0043065//positive regulation of apoptotic process;GO:0031069//hair follicle morphogenesis;GO:0030279//negative regulation of ossification;GO:0001708//cell fate specification;GO:0001837//epithelial to mesenchymal transition;GO:0003209//cardiac atrium morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0003162//atrioventricular node development;GO:0007409//axonogenesis;GO:0060253//negative regulation of glial cell proliferation;GO:0007440//foregut morphogenesis;GO:0030335//positive regulation of cell migration;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005509//calcium ion binding;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0004857//enzyme inhibitor activity;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0019899//enzyme binding;GO:0004872//receptor activity;GO:0001047//core promoter binding,K02599//Prion diseases;Notch signaling pathway;Dorso-ventral axis formation
4852,0,0,0,1,3,0,12,0,20,0,10,0,NPY;neuropeptide Y,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005623//cell,"GO:0021954//central nervous system neuron development;GO:0007586//digestion;GO:0007610//behavior;GO:0032100//positive regulation of appetite;GO:0008015//blood circulation;GO:0008217//regulation of blood pressure;GO:0007631//feeding behavior;GO:0021987//cerebral cortex development;GO:0006928//cellular component movement;GO:0007268//synaptic transmission;GO:0031175//neuron projection development;GO:0008283//cell proliferation;GO:0008343//adult feeding behavior;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0006816//calcium ion transport",GO:0005246//calcium channel regulator activity;GO:0001664//G-protein coupled receptor binding;GO:0005102//receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0005184//neuropeptide hormone activity,K05232//Alcoholism;Adipocytokine signaling pathway
4853,41,1,0,0,27,26,54,141,165,0,14,0,NOTCH2;notch 2,GO:0005929//cilium;GO:0043235//receptor complex;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005654//nucleoplasm,"GO:0043065//positive regulation of apoptotic process;GO:0007399//nervous system development;GO:0007275//multicellular organismal development;GO:0060674//placenta blood vessel development;GO:0006959//humoral immune response;GO:0006915//apoptotic process;GO:0007219//Notch signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007220//Notch receptor processing;GO:0006355//regulation of transcription, DNA-templated;GO:0060413//atrial septum morphogenesis;GO:0001701//in utero embryonic development;GO:0019827//stem cell maintenance;GO:0046849//bone remodeling;GO:0030097//hemopoiesis;GO:0001709//cell fate determination;GO:0007050//cell cycle arrest;GO:0007368//determination of left/right symmetry;GO:0030522//intracellular receptor signaling pathway;GO:0030513//positive regulation of BMP signaling pathway;GO:0009887//organ morphogenesis;GO:0002011//morphogenesis of an epithelial sheet;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0002437//inflammatory response to antigenic stimulus;GO:0061073//ciliary body morphogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0003184//pulmonary valve morphogenesis;GO:0061314//Notch signaling involved in heart development;GO:0030326//embryonic limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0016049//cell growth;GO:0072602//interleukin-4 secretion",GO:0004872//receptor activity;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0038049//ligand-activated RNA polymerase II transcription factor binding transcription factor activity,K02599//Notch signaling pathway;Dorso-ventral axis formation;Prion diseases
4854,1,0,0,0,0,28,33,178,79,6,9,0,NOTCH3;notch 3,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045665//negative regulation of neuron differentiation;GO:0007220//Notch receptor processing;GO:0010467//gene expression;GO:0030900//forebrain development;GO:0048663//neuron fate commitment;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007219//Notch signaling pathway;GO:0072104//glomerular capillary formation;GO:0006355//regulation of transcription, DNA-templated",GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019899//enzyme binding,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
4855,0,0,0,0,0,0,0,0,4,0,0,0,NOTCH4;notch 4,GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,"GO:0001763//morphogenesis of a branching structure;GO:0001709//cell fate determination;GO:0045602//negative regulation of endothelial cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0030097//hemopoiesis;GO:0030879//mammary gland development;GO:0030154//cell differentiation;GO:0001886//endothelial cell morphogenesis;GO:0001569//patterning of blood vessels;GO:0007219//Notch signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007220//Notch receptor processing;GO:0010467//gene expression;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0009790//embryo development;GO:0045893//positive regulation of transcription, DNA-templated",GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004872//receptor activity,K02599//Prion diseases;Notch signaling pathway;Dorso-ventral axis formation
4856,0,0,0,0,15,21,0,0,60,0,0,0,NOV;nephroblastoma overexpressed,GO:0030424//axon;GO:0005576//extracellular region;GO:0030425//dendrite;GO:0043231//intracellular membrane-bounded organelle;GO:0031012//extracellular matrix;GO:0043025//neuronal cell body,GO:0001558//regulation of cell growth;GO:0010468//regulation of gene expression,GO:0005520//insulin-like growth factor binding;GO:0008083//growth factor activity,-
4857,78,0,22,0,0,0,0,60,40,0,0,0,NOVA1;neuro-oncological ventral antigen 1,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,"GO:0007626//locomotory behavior;GO:0006396//RNA processing;GO:0051252//regulation of RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0007268//synaptic transmission",GO:0044822//poly(A) RNA binding;GO:0003729//mRNA binding;GO:0003723//RNA binding,-
4858,0,17,0,0,0,0,5,35,0,0,0,0,NOVA2;neuro-oncological ventral antigen 2,GO:0005634//nucleus,GO:0051252//regulation of RNA metabolic process,GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,-
4860,82,39,0,0,16,0,0,0,11,0,15,0,PNP;purine nucleoside phosphorylase,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0070970//interleukin-2 secretion;GO:0034418//urate biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0006148//inosine catabolic process;GO:0034356//NAD biosynthesis via nicotinamide riboside salvage pathway;GO:0006955//immune response;GO:0006139//nucleobase-containing compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006195//purine nucleotide catabolic process;GO:0043101//purine-containing compound salvage;GO:0006738//nicotinamide riboside catabolic process;GO:0042102//positive regulation of T cell proliferation;GO:0042493//response to drug,GO:0004731//purine-nucleoside phosphorylase activity;GO:0002060//purine nucleobase binding;GO:0008144//drug binding;GO:0042301//phosphate ion binding;GO:0001882//nucleoside binding,K03783//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Polyketide sugar unit biosynthesis;Metabolic pathways;Streptomycin biosynthesis;Nicotinate and nicotinamide metabolism
4861,15,0,1,6,9,0,0,0,8,0,1,0,NPAS1;neuronal PAS domain protein 1,GO:0005634//nucleus,"GO:0042711//maternal behavior;GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0001964//startle response;GO:0007417//central nervous system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0004871//signal transducer activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046983//protein dimerization activity,-
4862,74,0,2,0,42,0,8,59,40,151,12,0,NPAS2;neuronal PAS domain protein 2,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0045739//positive regulation of DNA repair;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0042745//circadian sleep/wake cycle;GO:0051775//response to redox state;GO:2001020//regulation of response to DNA damage stimulus;GO:0060548//negative regulation of cell death;GO:0007417//central nervous system development;GO:0045475//locomotor rhythm;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction",GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0051879//Hsp90 protein binding;GO:0001047//core promoter binding;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09026//Circadian rhythm - mammal
4863,0,0,0,9,0,0,102,0,24,110,9,0,"NPAT;nuclear protein, ataxia-telangiectasia locus",GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0097504//Gemini of coiled bodies;GO:0005730//nucleolus,"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0010468//regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0047485//protein N-terminus binding;GO:0008022//protein C-terminus binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity,-
4864,0,0,0,0,11,35,10,0,36,0,0,0,"NPC1;Niemann-Pick disease, type C1",GO:0005887//integral component of plasma membrane;GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0031902//late endosome membrane;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane,GO:0006486//protein glycosylation;GO:0090150//establishment of protein localization to membrane;GO:0031579//membrane raft organization;GO:0030301//cholesterol transport;GO:0007165//signal transduction;GO:0042632//cholesterol homeostasis;GO:0006897//endocytosis;GO:0006914//autophagy;GO:0060548//negative regulation of cell death;GO:0042493//response to drug;GO:0007041//lysosomal transport;GO:0033344//cholesterol efflux;GO:0016242//negative regulation of macroautophagy;GO:0071383//cellular response to steroid hormone stimulus;GO:0046686//response to cadmium ion;GO:0008206//bile acid metabolic process;GO:0007628//adult walking behavior;GO:0071404//cellular response to low-density lipoprotein particle stimulus;GO:0008203//cholesterol metabolic process,GO:0015248//sterol transporter activity;GO:0015485//cholesterol binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0008158//hedgehog receptor activity;GO:0004872//receptor activity,K12385//Lysosome
4867,0,0,0,0,0,46,0,0,54,1,0,370,NPHP1;nephronophthisis 1 (juvenile),GO:0016020//membrane;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005923//tight junction;GO:0035869//ciliary transition zone;GO:0031514//motile cilium;GO:0032391//photoreceptor connecting cilium;GO:0005912//adherens junction,GO:0007165//signal transduction;GO:0030030//cell projection organization;GO:0035845//photoreceptor cell outer segment organization;GO:0007632//visual behavior;GO:0060041//retina development in camera-type eye;GO:0048515//spermatid differentiation;GO:0016337//single organismal cell-cell adhesion;GO:0030036//actin cytoskeleton organization;GO:0034613//cellular protein localization;GO:0007588//excretion,GO:0005198//structural molecule activity;GO:0005515//protein binding,K04364//Neurotrophin signaling pathway;Hepatitis C;MAPK signaling pathway - fly;Osteoclast differentiation;Endometrial cancer;Non-small cell lung cancer;Dorso-ventral axis formation;Focal adhesion;Glioma;Jak-STAT signaling pathway;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Renal cell carcinoma;ErbB signaling pathway;Insulin signaling pathway;GnRH signaling pathway;Pathways in cancer;Chemokine signaling pathway;Gap junction;Prostate cancer;Alcoholism;K04438//Pathways in cancer;Chemokine signaling pathway;Bacterial invasion of epithelial cells;Insulin signaling pathway;Fc gamma R-mediated phagocytosis;Shigellosis;MAPK signaling pathway;Chronic myeloid leukemia;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;ErbB signaling pathway;Focal adhesion;Renal cell carcinoma
4868,0,0,0,0,0,0,11,47,36,49,13,0,"NPHS1;nephrosis 1, congenital, Finnish type (nephrin)",GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0036057//slit diaphragm;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane;GO:0042995//cell projection,GO:0072015//glomerular visceral epithelial cell development;GO:0007588//excretion;GO:0007519//skeletal muscle tissue development;GO:0007520//myoblast fusion;GO:0007155//cell adhesion;GO:0030838//positive regulation of actin filament polymerization;GO:0032836//glomerular basement membrane development;GO:0044062//regulation of excretion;GO:0007254//JNK cascade,GO:0051393//alpha-actinin binding;GO:0017022//myosin binding;GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0030507//spectrin binding,-
4869,75,161,0,68,425,28,1,0,23,0,0,0,"NPM1;nucleophosmin (nucleolar phosphoprotein B23, numatrin)",GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0031616//spindle pole centrosome;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005654//nucleoplasm,GO:0006334//nucleosome assembly;GO:0051259//protein oligomerization;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046599//regulation of centriole replication;GO:0060699//regulation of endoribonuclease activity;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0032071//regulation of endodeoxyribonuclease activity;GO:0008104//protein localization;GO:0016032//viral process;GO:0006913//nucleocytoplasmic transport;GO:0045727//positive regulation of translation;GO:0006281//DNA repair;GO:0006886//intracellular protein transport;GO:0060735//regulation of eIF2 alpha phosphorylation by dsRNA;GO:0034080//CENP-A containing nucleosome assembly;GO:0007165//signal transduction;GO:0010826//negative regulation of centrosome duplication;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0007569//cell aging;GO:0006950//response to stress;GO:0007098//centrosome cycle;GO:0042255//ribosome assembly,GO:0043024//ribosomal small subunit binding;GO:0051059//NF-kappaB binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0030957//Tat protein binding;GO:0019901//protein kinase binding;GO:0043023//ribosomal large subunit binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004860//protein kinase inhibitor activity;GO:0042393//histone binding;GO:0051082//unfolded protein binding,-
487,157,98,0,89,185,20,18,279,82,0,213,0,"ATP2A1;ATPase, Ca++ transporting, cardiac muscle, fast twitch 1",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0031095//platelet dense tubular network membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016529//sarcoplasmic reticulum;GO:0031673//H zone;GO:0048471//perinuclear region of cytoplasm;GO:0034704//calcium channel complex;GO:0005789//endoplasmic reticulum membrane;GO:0031674//I band;GO:0033017//sarcoplasmic reticulum membrane,GO:0034220//ion transmembrane transport;GO:0007596//blood coagulation;GO:0006942//regulation of striated muscle contraction;GO:0070588//calcium ion transmembrane transport;GO:0031448//positive regulation of fast-twitch skeletal muscle fiber contraction;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0034976//response to endoplasmic reticulum stress;GO:0008637//apoptotic mitochondrial changes;GO:0006200//ATP catabolic process;GO:0051659//maintenance of mitochondrion location;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0045988//negative regulation of striated muscle contraction;GO:0006816//calcium ion transport;GO:0008152//metabolic process;GO:0055085//transmembrane transport;GO:0032470//positive regulation of endoplasmic reticulum calcium ion concentration;GO:0070509//calcium ion import;GO:0090076//relaxation of skeletal muscle;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,GO:0005388//calcium-transporting ATPase activity;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005524//ATP binding,K05853//Cardiac muscle contraction;Pancreatic secretion;Calcium signaling pathway;Dilated cardiomyopathy;Alzheimer's disease;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC)
4878,0,0,0,0,0,0,2,0,0,0,0,0,NPPA;natriuretic peptide A,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0042629//mast cell granule;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0032868//response to insulin;GO:0007565//female pregnancy;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0006182//cGMP biosynthetic process;GO:0030308//negative regulation of cell growth;GO:0071260//cellular response to mechanical stimulus;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050880//regulation of blood vessel size;GO:0008217//regulation of blood pressure;GO:0001666//response to hypoxia,GO:0005102//receptor binding;GO:0005179//hormone activity;GO:0051428//peptide hormone receptor binding,-
4879,0,0,0,0,0,0,0,0,11,0,0,0,NPPB;natriuretic peptide B,GO:0043234//protein complex;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0050880//regulation of blood vessel size;GO:0007166//cell surface receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0035815//positive regulation of renal sodium excretion;GO:0043114//regulation of vascular permeability;GO:0042312//regulation of vasodilation;GO:0030308//negative regulation of cell growth;GO:0016525//negative regulation of angiogenesis;GO:0006182//cGMP biosynthetic process;GO:0007589//body fluid secretion;GO:0035810//positive regulation of urine volume;GO:0007168//receptor guanylyl cyclase signaling pathway,GO:0008613//diuretic hormone activity;GO:0005102//receptor binding;GO:0005179//hormone activity,-
488,0,0,0,0,23,16,53,74,81,44,3,0,"ATP2A2;ATPase, Ca++ transporting, cardiac muscle, slow twitch 2",GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031095//platelet dense tubular network membrane,GO:0010460//positive regulation of heart rate;GO:0006874//cellular calcium ion homeostasis;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0006984//ER-nucleus signaling pathway;GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0008544//epidermis development;GO:0055119//relaxation of cardiac muscle;GO:0008152//metabolic process;GO:0055085//transmembrane transport;GO:0045822//negative regulation of heart contraction;GO:0002026//regulation of the force of heart contraction;GO:0034220//ion transmembrane transport;GO:0007596//blood coagulation;GO:0006810//transport;GO:0007155//cell adhesion;GO:0070588//calcium ion transmembrane transport,GO:0008022//protein C-terminus binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005388//calcium-transporting ATPase activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0044548//S100 protein binding;GO:0086039//calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential,K05853//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Alzheimer's disease;Calcium signaling pathway;Dilated cardiomyopathy;Pancreatic secretion;Cardiac muscle contraction
4880,108,0,0,0,0,0,0,0,18,0,0,0,NPPC;natriuretic peptide C,GO:0030141//secretory granule;GO:0005615//extracellular space,GO:0001666//response to hypoxia;GO:0050880//regulation of blood vessel size;GO:0030823//regulation of cGMP metabolic process;GO:0051447//negative regulation of meiotic cell cycle;GO:0040014//regulation of multicellular organism growth;GO:0051053//negative regulation of DNA metabolic process;GO:0045909//positive regulation of vasodilation;GO:1900194//negative regulation of oocyte maturation;GO:0009791//post-embryonic development;GO:0044702//single organism reproductive process;GO:0003418//growth plate cartilage chondrocyte differentiation;GO:0048660//regulation of smooth muscle cell proliferation;GO:0003419//growth plate cartilage chondrocyte proliferation;GO:0008285//negative regulation of cell proliferation;GO:0045471//response to ethanol;GO:0006182//cGMP biosynthetic process;GO:0042493//response to drug;GO:0001503//ossification;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0030814//regulation of cAMP metabolic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0007168//receptor guanylyl cyclase signaling pathway,GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0005179//hormone activity;GO:0051428//peptide hormone receptor binding,-
4881,81,0,0,0,0,0,63,1,17,208,5,604,NPR1;natriuretic peptide receptor 1,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane,GO:0016525//negative regulation of angiogenesis;GO:0007589//body fluid secretion;GO:0042312//regulation of vasodilation;GO:0006468//protein phosphorylation;GO:0008217//regulation of blood pressure;GO:0007166//cell surface receptor signaling pathway;GO:0050880//regulation of blood vessel size;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0030828//positive regulation of cGMP biosynthetic process;GO:0035810//positive regulation of urine volume;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0006182//cGMP biosynthetic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0035556//intracellular signal transduction;GO:0042417//dopamine metabolic process;GO:0043114//regulation of vascular permeability;GO:0035815//positive regulation of renal sodium excretion,GO:0042562//hormone binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0005524//ATP binding;GO:0017046//peptide hormone binding;GO:0005525//GTP binding;GO:0016941//natriuretic peptide receptor activity;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0004383//guanylate cyclase activity,K12323//Vascular smooth muscle contraction;Purine metabolism
4882,0,0,0,0,1,0,0,36,5,0,0,274,NPR2;natriuretic peptide receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0060348//bone development;GO:0008217//regulation of blood pressure;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0007166//cell surface receptor signaling pathway;GO:0044702//single organism reproductive process;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0007165//signal transduction;GO:1900194//negative regulation of oocyte maturation;GO:0001503//ossification;GO:0006182//cGMP biosynthetic process;GO:0051447//negative regulation of meiotic cell cycle,GO:0004888//transmembrane signaling receptor activity;GO:0004383//guanylate cyclase activity;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0042562//hormone binding;GO:0016941//natriuretic peptide receptor activity;GO:0005525//GTP binding;GO:0017046//peptide hormone binding;GO:0004872//receptor activity,K12324//Vascular smooth muscle contraction;Purine metabolism
4883,0,25,1,121,112,0,23,0,106,0,26,0,NPR3;natriuretic peptide receptor 3,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0048015//phosphatidylinositol-mediated signaling;GO:0007194//negative regulation of adenylate cyclase activity;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0030157//pancreatic juice secretion;GO:0001501//skeletal system development;GO:0008217//regulation of blood pressure;GO:0002158//osteoclast proliferation;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0035810//positive regulation of urine volume;GO:0033688//regulation of osteoblast proliferation,GO:0017046//peptide hormone binding;GO:0016941//natriuretic peptide receptor activity;GO:0042562//hormone binding;GO:0008528//G-protein coupled peptide receptor activity;GO:0042803//protein homodimerization activity,-
4884,0,0,0,0,0,2,27,0,11,0,17,0,NPTX1;neuronal pentraxin I,GO:0030133//transport vesicle;GO:0005739//mitochondrion;GO:0043005//neuron projection;GO:0005886//plasma membrane,GO:0006839//mitochondrial transport;GO:0060385//axonogenesis involved in innervation;GO:0006810//transport;GO:0035865//cellular response to potassium ion;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0071333//cellular response to glucose stimulus;GO:0007268//synaptic transmission;GO:0007417//central nervous system development,GO:0046872//metal ion binding,-
4885,0,0,0,0,0,4,27,0,11,0,9,0,NPTX2;neuronal pentraxin II,GO:0005576//extracellular region,GO:0007268//synaptic transmission,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding,-
4886,0,0,0,0,8,0,0,0,2,0,15,0,NPY1R;neuropeptide Y receptor Y1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0003151//outflow tract morphogenesis;GO:0040014//regulation of multicellular organism growth;GO:0019233//sensory perception of pain;GO:0007626//locomotory behavior;GO:0006006//glucose metabolic process;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007631//feeding behavior;GO:0008217//regulation of blood pressure;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway",GO:0001602//pancreatic polypeptide receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0001601//peptide YY receptor activity;GO:0005515//protein binding,K04204//Neuroactive ligand-receptor interaction
4887,0,0,0,0,0,0,0,0,39,0,49,0,NPY2R;neuropeptide Y receptor Y2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0030818//negative regulation of cAMP biosynthetic process;GO:0003151//outflow tract morphogenesis;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:2000252//negative regulation of feeding behavior;GO:0001662//behavioral fear response;GO:0045785//positive regulation of cell adhesion;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0051048//negative regulation of secretion;GO:0051930//regulation of sensory perception of pain;GO:0007263//nitric oxide mediated signal transduction;GO:0090394//negative regulation of excitatory postsynaptic membrane potential;GO:0003214//cardiac left ventricle morphogenesis;GO:0002793//positive regulation of peptide secretion;GO:0007626//locomotory behavior;GO:0045987//positive regulation of smooth muscle contraction;GO:0033603//positive regulation of dopamine secretion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0031645//negative regulation of neurological system process;GO:0046903//secretion;GO:0007218//neuropeptide signaling pathway",GO:0005246//calcium channel regulator activity;GO:0004872//receptor activity;GO:0001601//peptide YY receptor activity;GO:0004983//neuropeptide Y receptor activity;GO:0005515//protein binding,K04205//Neuroactive ligand-receptor interaction
4889,0,0,0,0,0,42,0,0,47,0,0,0,NPY5R;neuropeptide Y receptor Y5,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0060112//generation of ovulation cycle rhythm;GO:0003151//outflow tract morphogenesis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0003214//cardiac left ventricle morphogenesis;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0007268//synaptic transmission;GO:0007218//neuropeptide signaling pathway;GO:0002675//positive regulation of acute inflammatory response;GO:0014050//negative regulation of glutamate secretion;GO:0042755//eating behavior",GO:0004983//neuropeptide Y receptor activity;GO:0001601//peptide YY receptor activity;GO:0001602//pancreatic polypeptide receptor activity,K04207//Neuroactive ligand-receptor interaction
489,111,0,0,0,1,0,2,0,20,0,10,459,"ATP2A3;ATPase, Ca++ transporting, ubiquitous",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0016529//sarcoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031095//platelet dense tubular network membrane,GO:0007596//blood coagulation;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0008152//metabolic process;GO:0006816//calcium ion transport,GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity,K05853//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Alzheimer's disease;Pancreatic secretion;Calcium signaling pathway;Dilated cardiomyopathy;Cardiac muscle contraction
4891,4,0,0,0,21,12,37,0,66,0,4,0,"SLC11A2;solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2",GO:0048471//perinuclear region of cytoplasm;GO:0031902//late endosome membrane;GO:0070826//paraferritin complex;GO:0055037//recycling endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005770//late endosome;GO:0016324//apical plasma membrane;GO:0045178//basal part of cell;GO:0045177//apical part of cell;GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0005903//brush border;GO:0016020//membrane;GO:0005773//vacuole;GO:0009986//cell surface;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm,GO:0035434//copper ion transmembrane transport;GO:0015676//vanadium ion transport;GO:0010288//response to lead ion;GO:0048813//dendrite morphogenesis;GO:0071356//cellular response to tumor necrosis factor;GO:1902600//hydrogen ion transmembrane transport;GO:0034599//cellular response to oxidative stress;GO:0034755//iron ion transmembrane transport;GO:0010039//response to iron ion;GO:0006879//cellular iron ion homeostasis;GO:0071456//cellular response to hypoxia;GO:0048821//erythrocyte development;GO:0007611//learning or memory;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0055085//transmembrane transport;GO:0006828//manganese ion transport;GO:0071281//cellular response to iron ion;GO:0071577//zinc ion transmembrane transport;GO:0006783//heme biosynthetic process;GO:0046686//response to cadmium ion;GO:0015684//ferrous iron transport;GO:0070574//cadmium ion transmembrane transport;GO:0006825//copper ion transport;GO:0060586//multicellular organismal iron ion homeostasis;GO:0003032//detection of oxygen;GO:0010042//response to manganese ion;GO:0015692//lead ion transport;GO:0035444//nickel cation transmembrane transport;GO:0070627//ferrous iron import;GO:0006824//cobalt ion transport;GO:0071421//manganese ion transmembrane transport;GO:0001666//response to hypoxia,GO:0015086//cadmium ion transmembrane transporter activity;GO:0015087//cobalt ion transmembrane transporter activity;GO:0005375//copper ion transmembrane transporter activity;GO:0015093//ferrous iron transmembrane transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0015099//nickel cation transmembrane transporter activity;GO:0005385//zinc ion transmembrane transporter activity;GO:0015085//calcium ion transmembrane transporter activity;GO:0015100//vanadium ion transmembrane transporter activity;GO:0005506//iron ion binding;GO:0030145//manganese ion binding;GO:0046870//cadmium ion binding;GO:0005507//copper ion binding;GO:0070835//chromium ion transmembrane transporter activity;GO:0015295//solute:proton symporter activity;GO:0005515//protein binding;GO:0050897//cobalt ion binding;GO:0016151//nickel cation binding;GO:0008270//zinc ion binding;GO:0005384//manganese ion transmembrane transporter activity;GO:0015094//lead ion transmembrane transporter activity,K12347//Mineral absorption;Lysosome
4892,107,0,0,0,0,23,0,44,73,0,0,0,NRAP;nebulin-related anchoring protein,GO:0030016//myofibril;GO:0005927//muscle tendon junction;GO:0005916//fascia adherens,-,GO:0003779//actin binding;GO:0017166//vinculin binding;GO:0051371//muscle alpha-actinin binding;GO:0008270//zinc ion binding,-
4893,0,48,1,21,130,4,35,109,16,0,0,0,NRAS;neuroblastoma RAS viral (v-ras) oncogene homolog,GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0050900//leukocyte migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0008542//visual learning;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0051146//striated muscle cell differentiation;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0007596//blood coagulation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0045596//negative regulation of cell differentiation;GO:0007265//Ras protein signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007411//axon guidance;GO:0000186//activation of MAPKK activity;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0035022//positive regulation of Rac protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0000165//MAPK cascade;GO:0006184//GTP catabolic process",GO:0005525//GTP binding;GO:0032403//protein complex binding,K07828//B cell receptor signaling pathway;Fc epsilon RI signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Tight junction;Melanogenesis;Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;Melanoma;Non-small cell lung cancer;Long-term potentiation;Prostate cancer;Insulin signaling pathway;Axon guidance;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;HTLV-I infection;Long-term depression;VEGF signaling pathway;Thyroid cancer;Glioma;Endometrial cancer;Alcoholism;Serotonergic synapse;Gap junction;GnRH signaling pathway;Pathways in cancer;Chemokine signaling pathway;Renal cell carcinoma;ErbB signaling pathway;Bladder cancer;MAPK signaling pathway
4897,3,0,0,0,0,3,0,58,25,0,7,0,NRCAM;neuronal cell adhesion molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0043194//axon initial segment;GO:0009897//external side of plasma membrane;GO:0045202//synapse;GO:0043005//neuron projection,GO:0001764//neuron migration;GO:0034113//heterotypic cell-cell adhesion;GO:0019227//neuronal action potential propagation;GO:0007417//central nervous system development;GO:0016337//single organismal cell-cell adhesion;GO:0007411//axon guidance;GO:0008104//protein localization;GO:0007416//synapse assembly;GO:0007413//axonal fasciculation;GO:0007409//axonogenesis;GO:0045162//clustering of voltage-gated sodium channels;GO:0030516//regulation of axon extension;GO:0001525//angiogenesis;GO:0031290//retinal ganglion cell axon guidance;GO:0045666//positive regulation of neuron differentiation,GO:0086080//protein binding involved in heterotypic cell-cell adhesion;GO:0005515//protein binding;GO:0030506//ankyrin binding,K06756//Cell adhesion molecules (CAMs)
4898,115,98,54,76,206,36,45,62,116,0,6,0,NRD1;nardilysin (N-arginine dibasic convertase),GO:0005829//cytosol;GO:0009986//cell surface,GO:0016477//cell migration;GO:0008283//cell proliferation;GO:0007528//neuromuscular junction development;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0006508//proteolysis;GO:0052548//regulation of endopeptidase activity,GO:0004222//metalloendopeptidase activity;GO:0048408//epidermal growth factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
4899,0,0,0,0,1,1,23,0,28,0,4,0,NRF1;nuclear respiratory factor 1,GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0006091//generation of precursor metabolites and energy;GO:0051602//response to electrical stimulus;GO:0032496//response to lipopolysaccharide;GO:0001666//response to hypoxia;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0007005//mitochondrion organization;GO:0032355//response to estradiol;GO:0031100//organ regeneration;GO:0051593//response to folic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K11831//Huntington's disease
490,0,0,0,0,0,20,16,7,128,0,0,0,"ATP2B1;ATPase, Ca++ transporting, plasma membrane 1",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0034220//ion transmembrane transport;GO:0007596//blood coagulation;GO:0006810//transport;GO:0008152//metabolic process;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,K05850//Salivary secretion;Calcium signaling pathway;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion
4900,0,0,0,9,17,0,0,0,0,0,3,0,"NRGN;neurogranin (protein kinase C substrate, RC3)",-,GO:0007399//nervous system development;GO:0007165//signal transduction,GO:0005516//calmodulin binding,-
4901,0,0,0,0,0,0,0,0,0,2,0,0,NRL;neural retina leucine zipper,GO:0005634//nucleus,GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0007468//regulation of rhodopsin gene expression;GO:0045872//positive regulation of rhodopsin gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046548//retinal rod cell development;GO:0006366//transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0043522//leucine zipper domain binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
4902,78,0,0,0,0,0,0,0,0,16,0,0,NRTN;neurturin,GO:0005576//extracellular region;GO:0030424//axon,GO:0021675//nerve development;GO:0000165//MAPK cascade;GO:0031175//neuron projection development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0001755//neural crest cell migration,GO:0008083//growth factor activity;GO:0005102//receptor binding,-
4904,0,37,0,17,138,0,1,0,8,40,0,0,YBX1;Y box binding protein 1,GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005689//U12-type spliceosomal complex;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0070937//CRD-mediated mRNA stability complex;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070934//CRD-mediated mRNA stabilization;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0051154//negative regulation of striated muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0051781//positive regulation of cell division;GO:0001701//in utero embryonic development",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0003723//RNA binding,-
4905,0,30,0,26,86,0,76,0,21,0,0,213,NSF;N-ethylmaleimide-sensitive factor,GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006887//exocytosis;GO:0001921//positive regulation of receptor recycling;GO:0006813//potassium ion transport;GO:0045026//plasma membrane fusion;GO:0006200//ATP catabolic process;GO:0007268//synaptic transmission;GO:0015031//protein transport,"GO:0042623//ATPase activity, coupled;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0017075//syntaxin-1 binding",K06027//Vasopressin-regulated water reabsorption;GABAergic synapse;Synaptic vesicle cycle
4907,0,0,1,8,13,0,0,0,4,0,30,0,"NT5E;5'-nucleotidase, ecto (CD73)",GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006195//purine nucleotide catabolic process;GO:0006196//AMP catabolic process;GO:0046086//adenosine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006259//DNA metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0050728//negative regulation of inflammatory response;GO:0046135//pyrimidine nucleoside catabolic process;GO:0016311//dephosphorylation;GO:0006206//pyrimidine nucleobase metabolic process,GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0008253//5'-nucleotidase activity,K01081//Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
4909,0,0,0,0,0,9,0,30,40,0,0,0,NTF4;neurotrophin 4,GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0060548//negative regulation of cell death;GO:0007402//ganglion mother cell fate determination;GO:0008052//sensory organ boundary specification;GO:0008544//epidermis development;GO:0060384//innervation;GO:0008344//adult locomotory behavior;GO:0042490//mechanoreceptor differentiation;GO:0007616//long-term memory;GO:0061193//taste bud development,GO:0008083//growth factor activity,K12457//MAPK signaling pathway;Neurotrophin signaling pathway
491,3,0,0,0,0,37,47,63,54,0,6,493,"ATP2B2;ATPase, Ca++ transporting, plasma membrane 2",GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005929//cilium;GO:0005886//plasma membrane,GO:0008361//regulation of cell size;GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0042428//serotonin metabolic process;GO:0051928//positive regulation of calcium ion transport;GO:0021702//cerebellar Purkinje cell differentiation;GO:0048167//regulation of synaptic plasticity;GO:0051480//cytosolic calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0050885//neuromuscular process controlling balance;GO:0046068//cGMP metabolic process;GO:0006816//calcium ion transport;GO:0050808//synapse organization;GO:0060088//auditory receptor cell stereocilium organization;GO:0007595//lactation;GO:0040011//locomotion;GO:0006200//ATP catabolic process;GO:0007596//blood coagulation;GO:0030182//neuron differentiation;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0090102//cochlea development;GO:0070588//calcium ion transmembrane transport;GO:0006996//organelle organization;GO:0021707//cerebellar granule cell differentiation;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0045299//otolith mineralization,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0030165//PDZ domain binding;GO:0008022//protein C-terminus binding;GO:0005509//calcium ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030899//calcium-dependent ATPase activity,K05850//Calcium signaling pathway;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion
4913,81,0,0,0,0,0,0,1,0,2,1,0,NTHL1;nth endonuclease III-like 1 (E. coli),GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006281//DNA repair;GO:0045008//depyrimidination;GO:0006284//base-excision repair;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006296//nucleotide-excision repair, DNA incision, 5'-to lesion","GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004519//endonuclease activity;GO:0019104//DNA N-glycosylase activity",K10773//Base excision repair
4914,6,0,0,0,0,0,26,0,14,0,0,605,"NTRK1;neurotrophic tyrosine kinase, receptor, type 1",GO:0031901//early endosome membrane;GO:0030424//axon;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0031902//late endosome membrane;GO:0005770//late endosome;GO:0009986//cell surface;GO:0005769//early endosome;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0031410//cytoplasmic vesicle;GO:0043234//protein complex;GO:0043025//neuronal cell body,"GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032320//positive regulation of Ras GTPase activity;GO:0009314//response to radiation;GO:0051599//response to hydrostatic pressure;GO:0071316//cellular response to nicotine;GO:0006468//protein phosphorylation;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0021553//olfactory nerve development;GO:0060385//axonogenesis involved in innervation;GO:1990090//cellular response to nerve growth factor stimulus;GO:0030183//B cell differentiation;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0007190//activation of adenylate cyclase activity;GO:0007411//axon guidance;GO:0045471//response to ethanol;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007202//activation of phospholipase C activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045766//positive regulation of angiogenesis;GO:0048485//sympathetic nervous system development;GO:0042493//response to drug;GO:0007611//learning or memory;GO:0010623//developmental programmed cell death;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0031667//response to nutrient levels;GO:0043068//positive regulation of programmed cell death;GO:0007623//circadian rhythm;GO:0048678//response to axon injury;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0042490//mechanoreceptor differentiation;GO:0007568//aging;GO:0051602//response to electrical stimulus;GO:0000186//activation of MAPKK activity;GO:0014823//response to activity;GO:0008285//negative regulation of cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0060009//Sertoli cell development;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0038180//nerve growth factor signaling pathway;GO:0007265//Ras protein signal transduction",GO:0005524//ATP binding;GO:0046875//ephrin receptor binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0048406//nerve growth factor binding;GO:0005166//neurotrophin p75 receptor binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043121//neurotrophin binding;GO:0010465//nerve growth factor receptor activity,K03176//Thyroid cancer;Transcriptional misregulation in cancer;Endocytosis;Neurotrophin signaling pathway;MAPK signaling pathway;Pathways in cancer;Apoptosis
4915,2,0,0,0,0,36,38,121,103,82,19,0,"NTRK2;neurotrophic tyrosine kinase, receptor, type 2",GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0097481//neuronal postsynaptic density;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0043197//dendritic spine;GO:0005829//cytosol;GO:0060076//excitatory synapse;GO:0043195//terminal bouton;GO:0043235//receptor complex;GO:0048786//presynaptic active zone;GO:0005887//integral component of plasma membrane,"GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0001570//vasculogenesis;GO:0007528//neuromuscular junction development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0046928//regulation of neurotransmitter secretion;GO:0051896//regulation of protein kinase B signaling;GO:0007612//learning;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0010996//response to auditory stimulus;GO:0014047//glutamate secretion;GO:0007190//activation of adenylate cyclase activity;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0050772//positive regulation of axonogenesis;GO:0050773//regulation of dendrite development;GO:0007616//long-term memory;GO:0021954//central nervous system neuron development;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0030182//neuron differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0008284//positive regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:2000811//negative regulation of anoikis;GO:0048935//peripheral nervous system neuron development;GO:0032314//regulation of Rac GTPase activity;GO:0046548//retinal rod cell development;GO:0048709//oligodendrocyte differentiation;GO:0042490//mechanoreceptor differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0007568//aging;GO:0007623//circadian rhythm;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007631//feeding behavior;GO:0021987//cerebral cortex development;GO:0060291//long-term synaptic potentiation;GO:0001764//neuron migration",GO:0060175//brain-derived neurotrophic factor-activated receptor activity;GO:0043121//neurotrophin binding;GO:0005524//ATP binding;GO:0048403//brain-derived neurotrophic factor binding;GO:0046875//ephrin receptor binding;GO:0042803//protein homodimerization activity,K04360//Neurotrophin signaling pathway;MAPK signaling pathway;Alcoholism
4916,0,0,0,4,0,4,0,48,4,0,4,0,"NTRK3;neurotrophic tyrosine kinase, receptor, type 3",GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0001764//neuron migration;GO:0071300//cellular response to retinoic acid;GO:0051412//response to corticosterone;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0090102//cochlea development;GO:0060548//negative regulation of cell death;GO:0048678//response to axon injury;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007623//circadian rhythm;GO:0048712//negative regulation of astrocyte differentiation;GO:0042490//mechanoreceptor differentiation;GO:0032148//activation of protein kinase B activity;GO:0046777//protein autophosphorylation;GO:0032856//activation of Ras GTPase activity;GO:0019056//modulation by virus of host transcription;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0000187//activation of MAPK activity;GO:0001933//negative regulation of protein phosphorylation;GO:0070306//lens fiber cell differentiation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0045471//response to ethanol;GO:0038179//neurotrophin signaling pathway;GO:0030335//positive regulation of cell migration;GO:0010628//positive regulation of gene expression;GO:0050927//positive regulation of positive chemotaxis;GO:0048665//neuron fate specification;GO:0008284//positive regulation of cell proliferation;GO:0048691//positive regulation of axon extension involved in regeneration,GO:0005030//neurotrophin receptor activity;GO:0002039//p53 binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043121//neurotrophin binding;GO:0005524//ATP binding;GO:0046875//ephrin receptor binding,K05101//Neurotrophin signaling pathway
4917,121,0,0,0,0,0,0,0,0,0,0,0,NTN3;netrin 3,GO:0005578//proteinaceous extracellular matrix;GO:0005794//Golgi apparatus,GO:0051149//positive regulation of muscle cell differentiation;GO:0042692//muscle cell differentiation;GO:0007411//axon guidance,GO:0005102//receptor binding,K06844//Axon guidance
4919,0,0,0,0,0,0,19,0,68,0,0,0,ROR1;receptor tyrosine kinase-like orphan receptor 1,GO:0005886//plasma membrane;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0017147//Wnt-protein binding;GO:0005515//protein binding,-
492,0,0,0,0,0,15,26,0,73,0,8,0,"ATP2B3;ATPase, Ca++ transporting, plasma membrane 3",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0031982//vesicle,GO:0034220//ion transmembrane transport;GO:0008219//cell death;GO:0007596//blood coagulation;GO:0006810//transport;GO:0008152//metabolic process;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005388//calcium-transporting ATPase activity;GO:0046872//metal ion binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding,K05850//Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Calcium signaling pathway
4920,0,0,0,0,1,8,20,0,9,0,0,0,ROR2;receptor tyrosine kinase-like orphan receptor 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane,"GO:0030335//positive regulation of cell migration;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0008285//negative regulation of cell proliferation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0007254//JNK cascade;GO:0001756//somitogenesis;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042472//inner ear morphogenesis;GO:0001502//cartilage condensation;GO:0007275//multicellular organismal development;GO:0030538//embryonic genitalia morphogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007165//signal transduction;GO:0030154//cell differentiation",GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005109//frizzled binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0017147//Wnt-protein binding,-
4921,0,0,0,0,0,6,0,0,12,0,0,0,DDR2;discoidin domain receptor tyrosine kinase 2,GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0038063//collagen-activated tyrosine kinase receptor signaling pathway;GO:0007155//cell adhesion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010763//positive regulation of fibroblast migration;GO:0007165//signal transduction;GO:0045860//positive regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0010715//regulation of extracellular matrix disassembly;GO:0035988//chondrocyte proliferation;GO:0031214//biomineral tissue development;GO:0090091//positive regulation of extracellular matrix disassembly;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0048146//positive regulation of fibroblast proliferation;GO:0030199//collagen fibril organization;GO:0030500//regulation of bone mineralization;GO:0045669//positive regulation of osteoblast differentiation;GO:0003416//endochondral bone growth;GO:0030198//extracellular matrix organization;GO:0001503//ossification,GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0038062//protein tyrosine kinase collagen receptor activity;GO:0005518//collagen binding;GO:0005524//ATP binding;GO:0005515//protein binding,-
4922,0,0,0,0,0,0,36,0,29,0,0,0,NTS;neurotensin,GO:0030133//transport vesicle;GO:0005576//extracellular region,GO:0050880//regulation of blood vessel size;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0005184//neuropeptide hormone activity,-
4923,0,0,0,0,0,0,1,0,12,0,0,0,NTSR1;neurotensin receptor 1 (high affinity),GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007268//synaptic transmission;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0007218//neuropeptide signaling pathway;GO:0008344//adult locomotory behavior,GO:0016492//G-protein coupled neurotensin receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding,K04211//Calcium signaling pathway;Neuroactive ligand-receptor interaction
492303,0,0,0,0,0,0,9,0,0,0,0,0,GEMIN8P4;gem (nuclear organelle) associated protein 8 pseudogene 4,-,-,-,K13136//RNA transport
492307,0,0,0,0,0,0,0,4,24,0,0,0,C8orf22;chromosome 8 open reading frame 22,-,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development,-,-
492311,0,32,0,9,0,0,11,0,1,0,0,0,IGIP;IgA-inducing protein,GO:0005576//extracellular region,-,-,-
4924,0,0,0,3,0,0,0,142,1,0,6,0,NUCB1;nucleobindin 1,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,-,GO:0005509//calcium ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,K12385//Lysosome
4925,40,0,0,15,13,0,0,58,36,0,0,0,NUCB2;nucleobindin 2,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005640//nuclear outer membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,-,GO:0005509//calcium ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,K12385//Lysosome
4926,0,160,7,54,219,0,38,3,39,0,73,0,NUMA1;nuclear mitotic apparatus protein 1,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005819//spindle;GO:0045177//apical part of cell;GO:0005654//nucleoplasm;GO:0030425//dendrite;GO:0005694//chromosome;GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0000922//spindle pole;GO:0016363//nuclear matrix;GO:0005876//spindle microtubule;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0060487//lung epithelial cell differentiation;GO:0000132//establishment of mitotic spindle orientation;GO:0006997//nucleus organization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0051321//meiotic cell cycle,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0005198//structural molecule activity,K12478//Tuberculosis;Endocytosis;Phagosome;K06267//ECM-receptor interaction
4927,0,31,1,9,20,1,0,0,25,6,13,0,NUP88;nucleoporin 88kDa,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005643//nuclear pore,GO:0044281//small molecule metabolic process;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0015758//glucose transport,GO:0005215//transporter activity,K14318//RNA transport
4928,88,27,0,34,113,12,0,0,80,0,0,0,NUP98;nucleoporin 98kDa,GO:0042405//nuclear inclusion body;GO:0005829//cytosol;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0034399//nuclear periphery;GO:0044615//nuclear pore nuclear basket;GO:0000776//kinetochore;GO:0031080//nuclear pore outer ring;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm,"GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0006913//nucleocytoplasmic transport;GO:0000059//protein import into nucleus, docking;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0051292//nuclear pore complex assembly;GO:0044281//small molecule metabolic process;GO:0006999//nuclear pore organization;GO:0015758//glucose transport;GO:0019221//cytokine-mediated signaling pathway;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0006260//DNA replication",GO:0017056//structural constituent of nuclear pore;GO:0005515//protein binding;GO:0005215//transporter activity;GO:0042277//peptide binding,K14297//Influenza A;RNA transport
4929,0,0,0,0,11,11,18,0,17,7,0,0,"NR4A2;nuclear receptor subfamily 4, group A, member 2",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0031668//cellular response to extracellular stimulus;GO:0042053//regulation of dopamine metabolic process;GO:0001764//neuron migration;GO:0043401//steroid hormone mediated signaling pathway;GO:0001666//response to hypoxia;GO:0043085//positive regulation of catalytic activity;GO:0009791//post-embryonic development;GO:0042416//dopamine biosynthetic process;GO:0042551//neuron maturation;GO:0017085//response to insecticide;GO:0007165//signal transduction;GO:0021986//habenula development;GO:0008344//adult locomotory behavior;GO:0010035//response to inorganic substance;GO:0030522//intracellular receptor signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0001975//response to amphetamine;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051866//general adaptation syndrome;GO:0034599//cellular response to oxidative stress;GO:0010467//gene expression;GO:0021952//central nervous system projection neuron axonogenesis;GO:0043576//regulation of respiratory gaseous exchange;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0071542//dopaminergic neuron differentiation;GO:0016265//death",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,-
493,172,0,0,0,12,10,1,1,2,303,12,1,"ATP2B4;ATPase, Ca++ transporting, plasma membrane 4",GO:0016020//membrane;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0030018//Z disc;GO:0005887//integral component of plasma membrane;GO:0005901//caveola,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0055074//calcium ion homeostasis;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0070588//calcium ion transmembrane transport;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007596//blood coagulation;GO:0051599//response to hydrostatic pressure;GO:0034220//ion transmembrane transport;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0006874//cellular calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0008152//metabolic process;GO:0071872//cellular response to epinephrine stimulus;GO:1902305//regulation of sodium ion transmembrane transport,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005388//calcium-transporting ATPase activity;GO:0097110//scaffold protein binding;GO:0017080//sodium channel regulator activity;GO:0030235//nitric-oxide synthase regulator activity;GO:0050998//nitric-oxide synthase binding;GO:0030346//protein phosphatase 2B binding;GO:0005516//calmodulin binding;GO:0005524//ATP binding,K05850//Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Salivary secretion
4931,0,0,0,9,3,27,0,0,91,0,0,0,NVL;nuclear VCP-like,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,K14571//Ribosome biogenesis in eukaryotes
4935,0,0,0,17,0,0,15,62,28,0,0,0,GPR143;G protein-coupled receptor 143,GO:0042470//melanosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0033162//melanosome membrane,GO:0006726//eye pigment biosynthetic process;GO:0032400//melanosome localization;GO:0007601//visual perception;GO:0007165//signal transduction;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0032402//melanosome transport;GO:0007218//neuropeptide signaling pathway;GO:0050848//regulation of calcium-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032438//melanosome organization;GO:0048015//phosphatidylinositol-mediated signaling,GO:0004930//G-protein coupled receptor activity;GO:0072545//tyrosine binding;GO:0005515//protein binding;GO:0072544//L-DOPA binding;GO:0035643//L-DOPA receptor activity;GO:0035240//dopamine binding,-
493753,0,0,55,47,30,0,0,0,0,0,0,0,COA5;cytochrome c oxidase assembly factor 5,GO:0005739//mitochondrion,-,-,-
493754,0,0,0,0,43,0,0,0,3,0,19,0,LOC493754;RAB guanine nucleotide exchange factor (GEF) 1 pseudogene,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K03914//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Regulation of actin cytoskeleton;Endocytosis;K11447//Transcriptional misregulation in cancer
4938,0,0,0,0,0,5,18,0,17,0,18,0,"OAS1;2'-5'-oligoadenylate synthetase 1, 40/46kDa",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0009615//response to virus;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0006006//glucose metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0060700//regulation of ribonuclease activity;GO:0035457//cellular response to interferon-alpha;GO:0042593//glucose homeostasis;GO:0051607//defense response to virus;GO:0051259//protein oligomerization;GO:0060337//type I interferon signaling pathway,GO:0005524//ATP binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003725//double-stranded RNA binding;GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K14216//Herpes simplex infection;Hepatitis C;Measles;Influenza A
493812,0,0,0,0,7,10,0,0,9,0,3,0,HCG11;HLA complex group 11 (non-protein coding),-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
493829,0,0,0,0,0,21,0,0,8,0,0,0,"TRIM72;tripartite motif containing 72, E3 ubiquitin protein ligase",GO:0030659//cytoplasmic vesicle membrane;GO:0042383//sarcolemma,GO:0007517//muscle organ development;GO:0006887//exocytosis;GO:0001778//plasma membrane repair;GO:0003012//muscle system process;GO:0051260//protein homooligomerization,GO:0001786//phosphatidylserine binding;GO:0008270//zinc ion binding,-
493856,0,0,0,0,9,0,0,0,30,0,21,0,CISD2;CDGSH iron sulfur domain 2,GO:0043234//protein complex;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane,GO:0010259//multicellular organismal aging;GO:0010506//regulation of autophagy;GO:0000422//mitochondrion degradation,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity",K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
493860,0,39,7,78,141,0,42,0,82,0,64,0,CCDC73;coiled-coil domain containing 73,-,-,-,K12478//Endocytosis;Phagosome;Tuberculosis
493861,0,0,0,0,0,0,24,0,0,0,0,0,EID3;EP300 interacting inhibitor of differentiation 3,"GO:0030915//Smc5-Smc6 complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000781//chromosome, telomeric region","GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006310//DNA recombination;GO:0006351//transcription, DNA-templated",GO:0042802//identical protein binding;GO:0005515//protein binding,-
493869,0,0,0,0,3,0,0,0,0,0,0,0,GPX8;glutathione peroxidase 8 (putative),GO:0016021//integral component of membrane;GO:0005788//endoplasmic reticulum lumen,GO:0055114//oxidation-reduction process;GO:0006979//response to oxidative stress,GO:0004601//peroxidase activity;GO:0004602//glutathione peroxidase activity,K00432//Two-component system;Arachidonic acid metabolism;Amyotrophic lateral sclerosis (ALS);Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Glutathione metabolism;Huntington's disease
4939,41,0,0,5,34,0,0,90,75,0,4,0,"OAS2;2'-5'-oligoadenylate synthetase 2, 69/71kDa",GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm,GO:0006139//nucleobase-containing compound metabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0060337//type I interferon signaling pathway;GO:0006401//RNA catabolic process;GO:0006486//protein glycosylation;GO:0051607//defense response to virus;GO:0006164//purine nucleotide biosynthetic process;GO:0018377//protein myristoylation,GO:0005524//ATP binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0046872//metal ion binding;GO:0003725//double-stranded RNA binding;GO:0008270//zinc ion binding,K14216//Herpes simplex infection;Hepatitis C;Measles;Influenza A
493901,0,0,0,0,0,0,45,63,8,0,0,0,"RNASE12;ribonuclease, RNase A family, 12 (non-active)",GO:0005576//extracellular region,-,GO:0003676//nucleic acid binding,-
493911,0,0,0,12,21,12,0,0,0,0,0,0,"PHOSPHO2;phosphatase, orphan 2",-,GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0033883//pyridoxal phosphatase activity,K13248//Vitamin B6 metabolism;Metabolic pathways
4940,0,54,1,8,11,64,7,38,8,127,0,0,"OAS3;2'-5'-oligoadenylate synthetase 3, 100kDa",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space,GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0060700//regulation of ribonuclease activity;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0006139//nucleobase-containing compound metabolic process;GO:0045071//negative regulation of viral genome replication,GO:0005524//ATP binding;GO:0001730//2'-5'-oligoadenylate synthetase activity;GO:0003725//double-stranded RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K14216//Herpes simplex infection;Hepatitis C;Measles;Influenza A
494115,0,40,0,23,15,0,0,0,53,0,0,0,"RBMXL1;RNA binding motif protein, X-linked-like 1",GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K12885//Spliceosome
494118,0,0,0,0,0,0,0,0,15,0,0,0,"SPANXN1;SPANX family, member N1",-,-,-,K11422//Lysine degradation;K14572//Ribosome biogenesis in eukaryotes
494127,0,0,0,0,0,0,0,44,0,0,0,0,LOC494127;NFYC pseudogene,-,-,-,K08066//Tuberculosis;Antigen processing and presentation
494143,0,0,0,0,5,0,16,70,24,0,0,0,"CHAC2;ChaC, cation transport regulator homolog 2 (E. coli)",-,-,-,-
494188,16,0,0,0,0,0,0,0,55,0,12,0,FBXO47;F-box protein 47,-,-,-,-
494197,0,0,0,0,0,13,0,0,0,0,0,0,"SPANXN5;SPANX family, member N5",-,-,-,-
4942,0,1,0,17,57,0,0,0,6,0,0,0,OAT;ornithine aminotransferase,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0008652//cellular amino acid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007601//visual perception;GO:0055129//L-proline biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0034214//protein hexamerization,GO:0030170//pyridoxal phosphate binding;GO:0004587//ornithine-oxo-acid transaminase activity,K00819//Biosynthesis of secondary metabolites;Arginine and proline metabolism;Metabolic pathways
4943,0,0,20,0,18,25,9,0,32,94,0,0,"TBC1D25;TBC1 domain family, member 25",GO:0005776//autophagic vacuole;GO:0031410//cytoplasmic vesicle,GO:0032851//positive regulation of Rab GTPase activity;GO:1901096//regulation of autophagic vacuole maturation;GO:0006914//autophagy,GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K12813//Spliceosome;K13136//RNA transport
494328,0,0,0,0,0,8,0,0,0,0,0,0,MIR379;microRNA 379,-,-,-,-
494329,0,0,0,0,0,0,0,0,1,0,0,0,MIR380;microRNA 380,-,-,-,-
494470,140,0,0,0,0,10,19,0,34,0,18,0,RNF165;ring finger protein 165,-,-,GO:0008270//zinc ion binding,K06058//Notch signaling pathway
494513,0,0,0,0,0,0,0,0,28,0,0,0,"DFNB59;deafness, autosomal recessive 59",GO:0043025//neuronal cell body,GO:0007605//sensory perception of sound,-,-
494514,0,35,0,21,28,0,0,69,19,0,18,0,TYMSOS;TYMS opposite strand,-,-,-,K00560//One carbon pool by folate;Metabolic pathways;Homologous recombination;Pyrimidine metabolism
494551,0,0,0,12,0,15,61,0,13,0,0,0,WEE2;WEE1 homolog 2 (S. pombe),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035038//female pronucleus assembly;GO:0007143//female meiotic division;GO:0060631//regulation of meiosis I;GO:0007067//mitotic nuclear division;GO:1900194//negative regulation of oocyte maturation;GO:0018108//peptidyl-tyrosine phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0000287//magnesium ion binding,K06632//Cell cycle
4946,0,0,0,0,8,0,0,0,0,0,0,0,OAZ1;ornithine decarboxylase antizyme 1,GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0006596//polyamine biosynthetic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport,GO:0005515//protein binding;GO:0008073//ornithine decarboxylase inhibitor activity,-
4947,0,17,0,0,18,0,0,0,0,0,0,0,OAZ2;ornithine decarboxylase antizyme 2,GO:0005829//cytosol;GO:0005634//nucleus,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0006595//polyamine metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport,GO:0005515//protein binding;GO:0008073//ornithine decarboxylase inhibitor activity,-
495,0,0,0,0,0,0,30,0,29,0,0,0,"ATP4A;ATPase, H+/K+ exchanging, alpha polypeptide",GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,GO:0006813//potassium ion transport;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0045851//pH reduction;GO:0055085//transmembrane transport;GO:0006754//ATP biosynthetic process;GO:0010155//regulation of proton transport;GO:0042493//response to drug;GO:0015991//ATP hydrolysis coupled proton transport,GO:0046982//protein heterodimerization activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0008900//hydrogen:potassium-exchanging ATPase activity,K01542//Collecting duct acid secretion;Oxidative phosphorylation;Gastric acid secretion
4951,0,0,0,0,0,27,0,0,0,0,0,0,OCM2;oncomodulin 2,-,-,GO:0005509//calcium ion binding,-
4952,0,24,1,35,136,1,30,0,26,0,0,0,OCRL;oculocerebrorenal syndrome of Lowe,GO:0005798//Golgi-associated vesicle;GO:0005634//nucleus;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005795//Golgi stack;GO:0005905//coated pit;GO:0001750//photoreceptor outer segment;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0030136//clathrin-coated vesicle;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane,GO:0044281//small molecule metabolic process;GO:0032314//regulation of Rac GTPase activity;GO:0006644//phospholipid metabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0001701//in utero embryonic development;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006629//lipid metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0042384//cilium assembly;GO:0006661//phosphatidylinositol biosynthetic process;GO:0032855//positive regulation of Rac GTPase activity,"GO:0048365//Rac GTPase binding;GO:0030675//Rac GTPase activator activity;GO:0052745//inositol phosphate phosphatase activity;GO:0005515//protein binding;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",K01099//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
4953,0,155,3,76,356,0,0,2,30,0,2,0,ODC1;ornithine decarboxylase 1,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0042176//regulation of protein catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0009615//response to virus;GO:0033387//putrescine biosynthetic process from ornithine;GO:0034641//cellular nitrogen compound metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0006595//polyamine metabolic process;GO:0044281//small molecule metabolic process;GO:0001822//kidney development,GO:0004586//ornithine decarboxylase activity;GO:0042803//protein homodimerization activity,K01581//Glutathione metabolism;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Lysine biosynthesis
4956,0,0,0,0,0,0,0,0,13,0,0,0,ODF1;outer dense fiber of sperm tails 1,GO:0005634//nucleus;GO:0001520//outer dense fiber,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0019904//protein domain specific binding,-
4957,0,0,0,28,57,32,31,0,41,0,13,1,ODF2;outer dense fiber of sperm tails 2,GO:0005634//nucleus;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0072372//primary cilium;GO:0005829//cytosol;GO:0005814//centriole;GO:0005813//centrosome;GO:0001520//outer dense fiber;GO:0036064//ciliary basal body,GO:0007275//multicellular organismal development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:1902017//regulation of cilium assembly;GO:0007286//spermatid development,GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0005198//structural molecule activity,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
4958,0,0,0,0,0,16,0,97,2,0,0,0,OMD;osteomodulin,GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen,GO:0007155//cell adhesion;GO:0042340//keratan sulfate catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process,-,-
496,0,0,0,0,14,0,0,0,5,0,2,0,"ATP4B;ATPase, H+/K+ exchanging, beta polypeptide",GO:0005886//plasma membrane;GO:0005890//sodium:potassium-exchanging ATPase complex,GO:0006814//sodium ion transport;GO:1902600//hydrogen ion transmembrane transport;GO:0010243//response to organonitrogen compound;GO:0034220//ion transmembrane transport;GO:0006813//potassium ion transport;GO:0032496//response to lipopolysaccharide;GO:0055085//transmembrane transport;GO:0007155//cell adhesion,GO:0008900//hydrogen:potassium-exchanging ATPase activity,K01543//Gastric acid secretion;Oxidative phosphorylation;Collecting duct acid secretion
4967,87,0,0,10,57,18,0,0,35,0,11,0,OGDH;oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide),GO:0045252//oxoglutarate dehydrogenase complex;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane,GO:0021766//hippocampus development;GO:0044281//small molecule metabolic process;GO:0021860//pyramidal neuron development;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0006091//generation of precursor metabolites and energy;GO:0006104//succinyl-CoA metabolic process;GO:0006096//glycolytic process;GO:0006734//NADH metabolic process;GO:0044237//cellular metabolic process;GO:0021695//cerebellar cortex development;GO:0006554//lysine catabolic process;GO:0061034//olfactory bulb mitral cell layer development;GO:0006103//2-oxoglutarate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0021794//thalamus development;GO:0021756//striatum development,GO:0030976//thiamine pyrophosphate binding;GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0051087//chaperone binding;GO:0046872//metal ion binding;GO:0031072//heat shock protein binding;GO:0034602//oxoglutarate dehydrogenase (NAD+) activity,K00164//Biosynthesis of secondary metabolites;Lysine degradation;Tryptophan metabolism;Microbial metabolism in diverse environments;Citrate cycle (TCA cycle);Metabolic pathways
4968,0,389,217,218,473,1,25,78,87,0,597,1,OGG1;8-oxoguanine DNA glycosylase,GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005739//mitochondrion,"GO:0051593//response to folic acid;GO:0006284//base-excision repair;GO:0002526//acute inflammatory response;GO:0006281//DNA repair;GO:0032355//response to estradiol;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair;GO:0009314//response to radiation;GO:0006979//response to oxidative stress;GO:0042493//response to drug;GO:0033158//regulation of protein import into nucleus, translocation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006355//regulation of transcription, DNA-templated;GO:0071276//cellular response to cadmium ion;GO:0045007//depurination;GO:0045471//response to ethanol","GO:0004519//endonuclease activity;GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0034039//8-oxo-7,8-dihydroguanine DNA N-glycosylase activity;GO:0003684//damaged DNA binding",K03660//Base excision repair
4969,0,0,0,0,0,0,1,0,1,0,0,0,OGN;osteoglycin,GO:0031012//extracellular matrix;GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0031982//vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0042340//keratan sulfate catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0018146//keratan sulfate biosynthetic process,GO:0005515//protein binding;GO:0008083//growth factor activity,-
497049,0,0,0,0,0,0,0,40,9,0,6,0,FLJ25758;MAP/microtubule affinity-regulating kinase 1 pseudogene,-,-,-,-
497189,0,0,0,0,0,17,0,0,0,0,0,0,"TIFAB;TRAF-interacting protein with forkhead-associated domain, family member B",-,-,-,-
497190,74,0,0,0,0,27,15,41,32,2,0,0,"CLEC18B;C-type lectin domain family 18, member B",GO:0005576//extracellular region,-,GO:0030246//carbohydrate binding,-
4973,0,0,0,0,0,0,13,0,12,0,0,0,OLR1;oxidized low density lipoprotein (lectin-like) receptor 1,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0016020//membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0007159//leukocyte cell-cell adhesion;GO:0050900//leukocyte migration;GO:0008015//blood circulation;GO:0008219//cell death;GO:0042157//lipoprotein metabolic process;GO:0006954//inflammatory response;GO:0042542//response to hydrogen peroxide;GO:0006508//proteolysis;GO:0006898//receptor-mediated endocytosis;GO:0007596//blood coagulation,GO:0005041//low-density lipoprotein receptor activity;GO:0005515//protein binding;GO:0030246//carbohydrate binding,K08763//PPAR signaling pathway;Phagosome
4974,0,0,0,0,3,0,0,0,56,0,10,0,OMG;oligodendrocyte myelin glycoprotein,GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,GO:0007155//cell adhesion;GO:0031102//neuron projection regeneration;GO:0050770//regulation of axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0048683//regulation of collateral sprouting of intact axon in response to injury;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0042802//identical protein binding,K08764//Peroxisome;Metabolic pathways;Primary bile acid biosynthesis;PPAR signaling pathway
4976,0,16,0,44,111,38,0,0,37,0,0,0,OPA1;optic atrophy 1 (autosomal dominant),GO:0030425//dendrite;GO:0005758//mitochondrial intermembrane space;GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0030061//mitochondrial crista,GO:0090398//cellular senescence;GO:0008053//mitochondrial fusion;GO:0000266//mitochondrial fission;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0007601//visual perception;GO:0007005//mitochondrion organization;GO:0001843//neural tube closure;GO:0007007//inner mitochondrial membrane organization;GO:0006915//apoptotic process;GO:0006184//GTP catabolic process;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0019896//axon transport of mitochondrion,GO:0003924//GTPase activity;GO:0000287//magnesium ion binding;GO:0005525//GTP binding;GO:0005515//protein binding,K01528//Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Bacterial invasion of epithelial cells;Endocytosis
497661,0,0,0,0,18,0,0,0,0,0,0,0,C18orf32;chromosome 18 open reading frame 32,-,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction,GO:0004871//signal transducer activity,K02880//Ribosome
4978,0,0,0,0,0,0,0,0,6,0,0,33,OPCML;opioid binding protein/cell adhesion molecule-like,GO:0005887//integral component of plasma membrane;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007155//cell adhesion;GO:0038003//opioid receptor signaling pathway;GO:0008038//neuron recognition,GO:0004985//opioid receptor activity,-
498,0,194,2,111,286,0,5,0,12,131,8,0,"ATP5A1;ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0045261//proton-transporting ATP synthase complex, catalytic core F(1);GO:0008180//COP9 signalosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion",GO:0006754//ATP biosynthetic process;GO:0022904//respiratory electron transport chain;GO:0006629//lipid metabolic process;GO:0009790//embryo development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process,"GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0022857//transmembrane transporter activity;GO:0016887//ATPase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0042288//MHC class I protein binding;GO:0005524//ATP binding",K02132//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
4982,0,0,0,0,0,15,0,80,18,0,0,0,"TNFRSF11B;tumor necrosis factor receptor superfamily, member 11b",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0006915//apoptotic process;GO:0001501//skeletal system development;GO:0007584//response to nutrient;GO:0043627//response to estrogen;GO:0046685//response to arsenic-containing substance;GO:0042489//negative regulation of odontogenesis of dentin-containing tooth;GO:0030198//extracellular matrix organization;GO:0042493//response to drug;GO:0007165//signal transduction;GO:0032026//response to magnesium ion;GO:0045779//negative regulation of bone resorption,GO:0004872//receptor activity;GO:0005125//cytokine activity,K05148//Cytokine-cytokine receptor interaction;Osteoclast differentiation
4983,0,38,0,84,132,15,36,0,35,0,0,31,OPHN1;oligophrenin 1,GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0030054//cell junction;GO:0043195//terminal bouton;GO:0043197//dendritic spine,"GO:0006930//substrate-dependent cell migration, cell extension;GO:0007165//signal transduction;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0032321//positive regulation of Rho GTPase activity;GO:0007411//axon guidance;GO:0048488//synaptic vesicle endocytosis;GO:0007399//nervous system development;GO:0030036//actin cytoskeleton organization;GO:0030100//regulation of endocytosis",GO:0003779//actin binding;GO:0035255//ionotropic glutamate receptor binding;GO:0005543//phospholipid binding;GO:0005100//Rho GTPase activator activity,K13736//Bacterial invasion of epithelial cells
4985,0,0,0,0,0,17,0,0,7,0,0,0,"OPRD1;opioid receptor, delta 1",GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0045121//membrane raft;GO:0043679//axon terminus;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0031226//intrinsic component of plasma membrane;GO:0032590//dendrite membrane;GO:0005887//integral component of plasma membrane,"GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0051924//regulation of calcium ion transport;GO:0032793//positive regulation of CREB transcription factor activity;GO:0051930//regulation of sensory perception of pain;GO:0051881//regulation of mitochondrial membrane potential;GO:0000060//protein import into nucleus, translocation;GO:0008344//adult locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0097237//cellular response to toxic substance;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007218//neuropeptide signaling pathway;GO:0038003//opioid receptor signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0071456//cellular response to hypoxia;GO:0032460//negative regulation of protein oligomerization;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0010629//negative regulation of gene expression",GO:0038046//enkephalin receptor activity;GO:0004985//opioid receptor activity;GO:0005515//protein binding,K04213//Neuroactive ligand-receptor interaction
49854,108,1,0,13,114,19,45,0,14,0,0,0,ZBTB21;zinc finger and BTB domain containing 21,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008327//methyl-CpG binding,-
49855,59,0,0,18,34,0,45,0,49,0,0,0,SCAPER;S-phase cyclin A-associated protein in the ER,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,-,GO:0046872//metal ion binding,-
49856,0,0,0,4,0,1,0,0,4,0,3,0,"WRAP73;WD repeat containing, antisense to TP73",GO:0005813//centrosome;GO:0005737//cytoplasm,-,-,-
4986,0,0,0,15,0,0,0,4,0,0,7,0,"OPRK1;opioid receptor, kappa 1",GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0046877//regulation of saliva secretion;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0038003//opioid receptor signaling pathway;GO:0006955//immune response;GO:0031635//adenylate cyclase-inhibiting opioid receptor signaling pathway;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007600//sensory perception;GO:0007610//behavior;GO:0019233//sensory perception of pain;GO:0051607//defense response to virus;GO:0007626//locomotory behavior,GO:0004985//opioid receptor activity;GO:0005515//protein binding;GO:0038048//dynorphin receptor activity,K04214//Neuroactive ligand-receptor interaction
49861,0,0,0,0,0,0,0,0,8,0,0,0,CLDN20;claudin 20,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//tight junction assembly;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
4987,0,0,4,0,0,17,0,0,41,0,0,0,OPRL1;opiate receptor-like 1,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007610//behavior;GO:0007600//sensory perception;GO:0019233//sensory perception of pain;GO:0038003//opioid receptor signaling pathway,GO:0005515//protein binding;GO:0001626//nociceptin receptor activity;GO:0004930//G-protein coupled receptor activity,K04216//Neuroactive ligand-receptor interaction
4988,84,0,0,0,1,17,26,0,75,0,35,0,"OPRM1;opioid receptor, mu 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,"GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0071315//cellular response to morphine;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0007626//locomotory behavior;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008285//negative regulation of cell proliferation;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0048149//behavioral response to ethanol;GO:0038003//opioid receptor signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0061358//negative regulation of Wnt protein secretion;GO:0050769//positive regulation of neurogenesis;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0007600//sensory perception;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0019233//sensory perception of pain;GO:0070588//calcium ion transmembrane transport;GO:0033554//cellular response to stress;GO:0070374//positive regulation of ERK1 and ERK2 cascade",GO:0001965//G-protein alpha-subunit binding;GO:0004930//G-protein coupled receptor activity;GO:0038047//morphine receptor activity;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0004979//beta-endorphin receptor activity,K04215//Morphine addiction;Neuroactive ligand-receptor interaction
4990,0,0,1,0,0,0,0,0,0,0,0,0,SIX6;SIX homeobox 6,GO:0005634//nucleus,GO:0009887//organ morphogenesis;GO:0007601//visual perception;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding,K15614//Transcriptional misregulation in cancer
4993,0,0,0,0,0,0,0,0,16,0,0,0,"OR2C1;olfactory receptor, family 2, subfamily C, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005938//cell cortex,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
4994,0,0,0,0,0,0,4,0,8,0,0,0,"OR3A1;olfactory receptor, family 3, subfamily A, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
4995,0,0,0,0,0,21,0,0,0,0,3,0,"OR3A2;olfactory receptor, family 3, subfamily A, member 2",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007606//sensory perception of chemical stimulus;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004872//receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
4998,0,0,0,0,0,0,0,0,34,0,0,0,"ORC1;origin recognition complex, subunit 1",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005664//nuclear origin of replication recognition complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0000082//G1/S transition of mitotic cell cycle,GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0005515//protein binding,K02603//Meiosis - yeast;Cell cycle - yeast;Cell cycle
4999,0,0,0,38,80,0,33,48,45,0,0,0,"ORC2;origin recognition complex, subunit 2",GO:0016020//membrane;GO:0000939//condensed chromosome inner kinetochore;GO:0005886//plasma membrane;GO:0005664//nuclear origin of replication recognition complex;GO:0005654//nucleoplasm;GO:0000792//heterochromatin;GO:0005634//nucleus,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle,GO:0005515//protein binding;GO:0003688//DNA replication origin binding,K02604//Cell cycle - yeast;Cell cycle;Meiosis - yeast
50,0,321,287,272,391,2,96,611,168,0,845,1,"ACO2;aconitase 2, mitochondrial",GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005759//mitochondrial matrix,GO:0006101//citrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0008219//cell death;GO:0006102//isocitrate metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,"GO:0005506//iron ion binding;GO:0003994//aconitate hydratase activity;GO:0051538//3 iron, 4 sulfur cluster binding;GO:0051539//4 iron, 4 sulfur cluster binding","K01681//Biosynthesis of secondary metabolites;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Citrate cycle (TCA cycle);Phenylalanine, tyrosine and tryptophan biosynthesis;Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments"
5000,50,0,33,38,80,0,0,0,55,73,43,0,"ORC4;origin recognition complex, subunit 4",GO:0005664//nuclear origin of replication recognition complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle,GO:0003688//DNA replication origin binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0005524//ATP binding,K02606//Cell cycle - yeast;Cell cycle;Meiosis - yeast
5001,0,0,0,0,0,11,14,49,37,0,0,0,"ORC5;origin recognition complex, subunit 5",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005664//nuclear origin of replication recognition complex,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006270//DNA replication initiation;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication,GO:0005524//ATP binding;GO:0003688//DNA replication origin binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K02607//Meiosis - yeast;Cell cycle;Cell cycle - yeast
5002,0,0,0,0,0,0,0,84,30,0,0,0,"SLC22A18;solute carrier family 22, member 18",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005635//nuclear envelope;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0055085//transmembrane transport;GO:0015893//drug transport;GO:0007588//excretion;GO:0015695//organic cation transport;GO:0006855//drug transmembrane transport,GO:0015293//symporter activity;GO:0031625//ubiquitin protein ligase binding;GO:0015238//drug transmembrane transporter activity,-
5003,8,11,0,10,6,0,11,0,1,0,25,0,"SLC22A18AS;solute carrier family 22 (organic cation transporter), member 18 antisense",-,-,-,-
5004,0,0,0,0,0,0,0,0,3,0,10,0,ORM1;orosomucoid 1,GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0006953//acute-phase response;GO:0006810//transport;GO:0002682//regulation of immune system process;GO:0006954//inflammatory response,GO:0005515//protein binding,-
5005,0,0,0,0,18,0,0,0,0,0,0,0,ORM2;orosomucoid 2,GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0006953//acute-phase response;GO:0006810//transport;GO:0002682//regulation of immune system process,-,-
5007,0,65,0,48,171,0,45,5,56,92,46,0,OSBP;oxysterol binding protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0005730//nucleolus,GO:0006869//lipid transport,GO:0008142//oxysterol binding,-
5009,0,0,0,0,0,0,1,0,7,0,0,0,OTC;ornithine carbamoyltransferase,GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0001889//liver development;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0070781//response to biotin;GO:0007494//midgut development;GO:0010043//response to zinc ion;GO:0000050//urea cycle;GO:0042493//response to drug;GO:0034641//cellular nitrogen compound metabolic process;GO:0006526//arginine biosynthetic process;GO:0097272//ammonia homeostasis;GO:0070207//protein homotrimerization;GO:0006593//ornithine catabolic process;GO:0019240//citrulline biosynthetic process,GO:0005543//phospholipid binding;GO:0042301//phosphate ion binding;GO:0016597//amino acid binding;GO:0004585//ornithine carbamoyltransferase activity,K00611//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Arginine and proline metabolism;Fructose and mannose metabolism;Other glycan degradation;Metabolic pathways
501,0,44,28,74,267,0,19,1,31,0,7,0,"ALDH7A1;aldehyde dehydrogenase 7 family, member A1",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0034641//cellular nitrogen compound metabolic process;GO:0006554//lysine catabolic process;GO:0044281//small molecule metabolic process;GO:0019285//glycine betaine biosynthetic process from choline;GO:0007605//sensory perception of sound;GO:0055114//oxidation-reduction process;GO:0006081//cellular aldehyde metabolic process,GO:0005515//protein binding;GO:0004029//aldehyde dehydrogenase (NAD) activity;GO:0008802//betaine-aldehyde dehydrogenase activity;GO:0004043//L-aminoadipate-semialdehyde dehydrogenase activity,"K14085//Metabolic pathways;Pyruvate metabolism;Propanoate metabolism;Lysine degradation;Fatty acid metabolism;Arginine and proline metabolism;Histidine metabolism;Ascorbate and aldarate metabolism;Tryptophan metabolism;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;beta-Alanine metabolism;Glycerolipid metabolism;Lysine biosynthesis;Glycolysis / Gluconeogenesis"
5010,0,0,0,0,0,26,4,0,18,0,3,0,CLDN11;claudin 11,GO:0005923//tight junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0045178//basal part of cell,GO:0008366//axon ensheathment;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0007283//spermatogenesis,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Cell adhesion molecules (CAMs);Tight junction
5013,0,0,0,0,6,0,0,4,14,0,0,0,OTX1;orthodenticle homeobox 1,GO:0005634//nucleus,GO:0042472//inner ear morphogenesis;GO:0022037//metencephalon development;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030901//midbrain development;GO:0048852//diencephalon morphogenesis,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
5015,0,0,0,0,0,0,53,0,0,0,0,0,OTX2;orthodenticle homeobox 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0043234//protein complex,"GO:0048852//diencephalon morphogenesis;GO:0007411//axon guidance;GO:0008589//regulation of smoothened signaling pathway;GO:0030900//forebrain development;GO:0007492//endoderm development;GO:0009953//dorsal/ventral pattern formation;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0032525//somite rostral/caudal axis specification;GO:0090009//primitive streak formation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001708//cell fate specification;GO:0022037//metencephalon development;GO:0042472//inner ear morphogenesis;GO:0006461//protein complex assembly;GO:0040019//positive regulation of embryonic development;GO:0042706//eye photoreceptor cell fate commitment;GO:0048664//neuron fate determination;GO:2000543//positive regulation of gastrulation;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0008190//eukaryotic initiation factor 4E binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
5016,0,12,0,0,12,0,0,0,18,0,0,0,"OVGP1;oviductal glycoprotein 1, 120kDa",GO:0030133//transport vesicle;GO:0005829//cytosol,GO:0007339//binding of sperm to zona pellucida;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:0007565//female pregnancy;GO:0005975//carbohydrate metabolic process;GO:0032504//multicellular organism reproduction;GO:0006032//chitin catabolic process;GO:0007338//single fertilization,GO:0004568//chitinase activity,K01183//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Metabolic pathways
5017,34,1,0,0,0,0,0,0,8,23,0,37,OVOL1;ovo-like zinc finger 1,GO:0005634//nucleus,"GO:0001822//kidney development;GO:1901994//negative regulation of meiotic cell cycle phase transition;GO:0009913//epidermal cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0007283//spermatogenesis;GO:0051729//germline cell cycle switching, mitotic to meiotic cell cycle;GO:0007010//cytoskeleton organization",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872//metal ion binding,-
5018,0,0,0,13,12,35,0,0,18,0,3,0,OXA1L;oxidase (cytochrome c) assembly 1-like,GO:0032592//integral component of mitochondrial membrane;GO:0043234//protein complex;GO:0005746//mitochondrial respiratory chain;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion,GO:0051354//negative regulation of oxidoreductase activity;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0006461//protein complex assembly;GO:0051205//protein insertion into membrane;GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly;GO:0009060//aerobic respiration;GO:0055114//oxidation-reduction process;GO:0051262//protein tetramerization;GO:0032780//negative regulation of ATPase activity,GO:0097177//mitochondrial ribosome binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K03217//ABC transporters;Metabolic pathways;Bacterial secretion system;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Protein export
5019,0,0,1,12,88,39,18,99,38,0,0,0,OXCT1;3-oxoacid CoA transferase 1,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0007584//response to nutrient;GO:0071229//cellular response to acid chemical;GO:0071333//cellular response to glucose stimulus;GO:0032024//positive regulation of insulin secretion;GO:0009725//response to hormone;GO:0042594//response to starvation;GO:0060612//adipose tissue development;GO:0007420//brain development;GO:0042182//ketone catabolic process;GO:0045471//response to ethanol;GO:0014823//response to activity;GO:0042493//response to drug;GO:0046952//ketone body catabolic process;GO:0044255//cellular lipid metabolic process;GO:0007507//heart development;GO:0044281//small molecule metabolic process,GO:0008260//3-oxoacid CoA-transferase activity;GO:0042803//protein homodimerization activity,"K01027//Valine, leucine and isoleucine degradation;Butanoate metabolism;Synthesis and degradation of ketone bodies"
5020,0,0,0,0,0,0,0,0,6,0,0,0,OXT;oxytocin/neurophysin I prepropeptide,GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0005576//extracellular region;GO:0043195//terminal bouton,GO:0032094//response to food;GO:0010701//positive regulation of norepinephrine secretion;GO:0045777//positive regulation of blood pressure;GO:0060455//negative regulation of gastric acid secretion;GO:0045925//positive regulation of female receptivity;GO:0051384//response to glucocorticoid;GO:0051930//regulation of sensory perception of pain;GO:0002027//regulation of heart rate;GO:0043434//response to peptide hormone;GO:0045778//positive regulation of ossification;GO:0001975//response to amphetamine;GO:0051591//response to cAMP;GO:0030431//sleep;GO:0032526//response to retinoic acid;GO:0045776//negative regulation of blood pressure;GO:0051965//positive regulation of synapse assembly;GO:0032570//response to progesterone;GO:0007165//signal transduction;GO:0050806//positive regulation of synaptic transmission;GO:0051602//response to electrical stimulus;GO:0035815//positive regulation of renal sodium excretion;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0014823//response to activity;GO:0042713//sperm ejaculation;GO:0042538//hyperosmotic salinity response;GO:0045472//response to ether;GO:0042711//maternal behavior;GO:0034695//response to prostaglandin E;GO:0009744//response to sucrose;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060406//positive regulation of penile erection;GO:0007565//female pregnancy;GO:0060179//male mating behavior;GO:0042220//response to cocaine;GO:0007507//heart development;GO:0032308//positive regulation of prostaglandin secretion;GO:0002125//maternal aggressive behavior;GO:0042755//eating behavior;GO:0035811//negative regulation of urine volume;GO:0035176//social behavior;GO:0060450//positive regulation of hindgut contraction;GO:0007625//grooming behavior;GO:0007613//memory;GO:0032355//response to estradiol;GO:0042756//drinking behavior,GO:0005185//neurohypophyseal hormone activity;GO:0031855//oxytocin receptor binding,-
5021,7,0,0,9,12,15,0,0,33,0,0,0,OXTR;oxytocin receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005913//cell-cell adherens junction;GO:0005902//microvillus;GO:0016324//apical plasma membrane,"GO:0051965//positive regulation of synapse assembly;GO:0032570//response to progesterone;GO:0001967//suckling behavior;GO:0030431//sleep;GO:0001975//response to amphetamine;GO:0034059//response to anoxia;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0070371//ERK1 and ERK2 cascade;GO:0043434//response to peptide hormone;GO:0034097//response to cytokine;GO:0060137//maternal process involved in parturition;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0060455//negative regulation of gastric acid secretion;GO:0042493//response to drug;GO:0045777//positive regulation of blood pressure;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010701//positive regulation of norepinephrine secretion;GO:0032355//response to estradiol;GO:0007613//memory;GO:0021537//telencephalon development;GO:0060206//estrous cycle phase;GO:0007595//lactation;GO:0006936//muscle contraction;GO:0007166//cell surface receptor signaling pathway;GO:0035176//social behavior;GO:0042755//eating behavior;GO:0042220//response to cocaine;GO:0007507//heart development;GO:0048565//digestive tract development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0042711//maternal behavior;GO:0060406//positive regulation of penile erection;GO:0007565//female pregnancy;GO:0042713//sperm ejaculation;GO:0070474//positive regulation of uterine smooth muscle contraction",GO:0017046//peptide hormone binding;GO:0004990//oxytocin receptor activity;GO:0005000//vasopressin receptor activity,K04229//Neuroactive ligand-receptor interaction;Calcium signaling pathway
5023,80,0,1,0,0,0,0,0,26,0,3,0,"P2RX1;purinergic receptor P2X, ligand-gated ion channel, 1",GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0043005//neuron projection;GO:0045211//postsynaptic membrane;GO:0005639//integral component of nuclear inner membrane;GO:0043234//protein complex;GO:0031240//external side of cell outer membrane;GO:0005887//integral component of plasma membrane,"GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0003056//regulation of vascular smooth muscle contraction;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0051291//protein heterooligomerization;GO:0051924//regulation of calcium ion transport;GO:0006810//transport;GO:0046513//ceramide biosynthetic process;GO:0007596//blood coagulation;GO:0008217//regulation of blood pressure;GO:0007320//insemination;GO:0033198//response to ATP;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051260//protein homooligomerization;GO:0019228//neuronal action potential;GO:0002554//serotonin secretion by platelet;GO:0042310//vasoconstriction;GO:0043270//positive regulation of ion transport;GO:0035249//synaptic transmission, glutamatergic;GO:0006812//cation transport;GO:0006811//ion transport",GO:0005262//calcium channel activity;GO:0008270//zinc ion binding;GO:0008144//drug binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellular ATP-gated cation channel activity;GO:0005261//cation channel activity;GO:0005524//ATP binding,K05215//Neuroactive ligand-receptor interaction;Calcium signaling pathway
5024,0,0,0,0,0,24,0,0,9,0,0,0,"P2RX3;purinergic receptor P2X, ligand-gated ion channel, 3",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0043195//terminal bouton;GO:0005791//rough endoplasmic reticulum;GO:0043197//dendritic spine;GO:0005639//integral component of nuclear inner membrane;GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0045121//membrane raft,GO:0030432//peristalsis;GO:0048266//behavioral response to pain;GO:0019228//neuronal action potential;GO:0009408//response to heat;GO:0048167//regulation of synaptic plasticity;GO:0009409//response to cold;GO:0033198//response to ATP;GO:0051260//protein homooligomerization;GO:0009743//response to carbohydrate;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0001666//response to hypoxia;GO:0006810//transport;GO:0050909//sensory perception of taste;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0007165//signal transduction;GO:0014832//urinary bladder smooth muscle contraction;GO:0050850//positive regulation of calcium-mediated signaling;GO:0007274//neuromuscular synaptic transmission,GO:0004931//extracellular ATP-gated cation channel activity;GO:0001614//purinergic nucleotide receptor activity;GO:0005524//ATP binding,K05217//Neuroactive ligand-receptor interaction;Calcium signaling pathway
5025,0,1,3,4,0,0,29,61,38,0,7,139,"P2RX4;purinergic receptor P2X, ligand-gated ion channel, 4",GO:0043195//terminal bouton;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0014069//postsynaptic density;GO:0045177//apical part of cell;GO:0043025//neuronal cell body;GO:0005765//lysosomal membrane;GO:0043197//dendritic spine;GO:0005639//integral component of nuclear inner membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction,GO:0042311//vasodilation;GO:0008217//regulation of blood pressure;GO:0034220//ion transmembrane transport;GO:0032308//positive regulation of prostaglandin secretion;GO:0006810//transport;GO:0097190//apoptotic signaling pathway;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0050850//positive regulation of calcium-mediated signaling;GO:0019233//sensory perception of pain;GO:0051899//membrane depolarization;GO:0042118//endothelial cell activation;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0007165//signal transduction;GO:0034405//response to fluid shear stress;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0051928//positive regulation of calcium ion transport;GO:0006809//nitric oxide biosynthetic process;GO:0002028//regulation of sodium ion transport;GO:0006816//calcium ion transport;GO:0055119//relaxation of cardiac muscle;GO:0071318//cellular response to ATP;GO:0019228//neuronal action potential;GO:0051260//protein homooligomerization;GO:0001894//tissue homeostasis;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0033198//response to ATP;GO:0055117//regulation of cardiac muscle contraction;GO:0045429//positive regulation of nitric oxide biosynthetic process,GO:0045296//cadherin binding;GO:0001614//purinergic nucleotide receptor activity;GO:0008144//drug binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding;GO:0005102//receptor binding;GO:0004931//extracellular ATP-gated cation channel activity;GO:0005507//copper ion binding,K05218//Calcium signaling pathway;Neuroactive ligand-receptor interaction
5027,0,0,0,0,0,84,0,0,0,0,0,0,"P2RX7;purinergic receptor P2X, ligand-gated ion channel, 7",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0032059//bleb;GO:0005737//cytoplasm;GO:0005639//integral component of nuclear inner membrane,"GO:0032060//bleb assembly;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0006812//cation transport;GO:0002028//regulation of sodium ion transport;GO:0033198//response to ATP;GO:0051709//regulation of killing of cells of other organism;GO:0046931//pore complex assembly;GO:0045087//innate immune response;GO:0097190//apoptotic signaling pathway;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0051495//positive regulation of cytoskeleton organization;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0030501//positive regulation of bone mineralization;GO:0045779//negative regulation of bone resorption;GO:0045919//positive regulation of cytolysis;GO:0019233//sensory perception of pain;GO:0051899//membrane depolarization;GO:0043409//negative regulation of MAPK cascade",GO:0005102//receptor binding;GO:0001614//purinergic nucleotide receptor activity;GO:0004931//extracellular ATP-gated cation channel activity;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0001530//lipopolysaccharide binding,K05220//Calcium signaling pathway;Neuroactive ligand-receptor interaction
5028,96,1,0,9,32,0,0,2,16,0,13,349,"P2RY1;purinergic receptor P2Y, G-protein coupled, 1",GO:0044297//cell body;GO:0016324//apical plasma membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0097481//neuronal postsynaptic density;GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0016323//basolateral plasma membrane,GO:0046887//positive regulation of hormone secretion;GO:0072659//protein localization to plasma membrane;GO:0043270//positive regulation of ion transport;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0090075//relaxation of muscle;GO:0007186//G-protein coupled receptor signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:0007420//brain development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060406//positive regulation of penile erection;GO:0010469//regulation of receptor activity;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0042755//eating behavior;GO:0051100//negative regulation of binding;GO:0007596//blood coagulation;GO:0070848//response to growth factor;GO:0042312//regulation of vasodilation;GO:0001934//positive regulation of protein phosphorylation;GO:0010700//negative regulation of norepinephrine secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019233//sensory perception of pain;GO:0007568//aging;GO:0001973//adenosine receptor signaling pathway;GO:0030168//platelet activation;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0004872//receptor activity;GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0005524//ATP binding;GO:0031686//A1 adenosine receptor binding;GO:0045032//ADP-activated nucleotide receptor activity;GO:0045031//ATP-activated nucleotide receptor activity;GO:0097110//scaffold protein binding;GO:0043531//ADP binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K04270//Neuroactive ligand-receptor interaction
5029,0,0,0,0,0,15,0,84,42,6,12,0,"P2RY2;purinergic receptor P2Y, G-protein coupled, 2",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway;GO:0042312//regulation of vasodilation;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006873//cellular ion homeostasis;GO:0070257//positive regulation of mucus secretion,GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004872//receptor activity,K04269//Neuroactive ligand-receptor interaction
5030,0,0,0,0,0,0,11,0,22,0,0,0,"P2RY4;pyrimidinergic receptor P2Y, G-protein coupled, 4",GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0030321//transepithelial chloride transport,GO:0005524//ATP binding;GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0045030//UTP-activated nucleotide receptor activity,K04271//Neuroactive ligand-receptor interaction
5031,0,0,0,0,0,22,9,0,0,0,7,0,"P2RY6;pyrimidinergic receptor P2Y, G-protein coupled, 6",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0045028//G-protein coupled purinergic nucleotide receptor activity;GO:0004930//G-protein coupled receptor activity,K04272//Neuroactive ligand-receptor interaction
5033,0,0,0,1,0,0,0,0,14,0,0,0,"P4HA1;prolyl 4-hydroxylase, alpha polypeptide I",GO:0005788//endoplasmic reticulum lumen;GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle,GO:0030199//collagen fibril organization;GO:0055114//oxidation-reduction process;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline,"GO:0005515//protein binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding;GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding",K00472//Metabolic pathways;Arginine and proline metabolism
5034,0,24,1,37,39,0,0,2,22,157,0,0,"P4HB;prolyl 4-hydroxylase, beta polypeptide",GO:0005788//endoplasmic reticulum lumen;GO:0005925//focal adhesion;GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0045454//cell redox homeostasis;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0006457//protein folding;GO:0044281//small molecule metabolic process;GO:0071456//cellular response to hypoxia;GO:0042157//lipoprotein metabolic process;GO:0030198//extracellular matrix organization;GO:0034976//response to endoplasmic reticulum stress,GO:0046982//protein heterodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity;GO:0004656//procollagen-proline 4-dioxygenase activity,K09580//Protein processing in endoplasmic reticulum
503497,0,0,0,0,0,0,0,0,15,5,0,0,"MS4A13;membrane-spanning 4-domains, subfamily A, member 13",GO:0016021//integral component of membrane,-,-,-
503519,17,0,0,0,0,0,0,0,14,0,0,0,LINC00929;long intergenic non-protein coding RNA 929,-,-,-,-
503538,0,0,0,12,19,23,21,0,10,0,33,0,A1BG-AS1;A1BG antisense RNA 1,-,-,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways;K14377//Osteoclast differentiation;K14443//RNA degradation
503542,248,78,101,55,96,2,0,296,20,0,217,0,SPRN;shadow of prion protein homolog (zebrafish),GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0031225//anchored component of membrane;GO:0031982//vesicle,GO:0006606//protein import into nucleus,GO:0003676//nucleic acid binding,-
503582,0,0,0,0,0,19,0,0,28,0,10,0,ARGFX;arginine-fifty homeobox,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
5036,0,0,0,31,53,0,0,0,33,0,0,0,"PA2G4;proliferation-associated 2G4, 38kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0006417//regulation of translation;GO:0007050//cell cycle arrest;GO:0006364//rRNA processing;GO:0008283//cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K05084//Calcium signaling pathway;ErbB signaling pathway;Endocytosis
503640,0,0,0,0,0,0,0,0,13,0,0,0,ARGFXP2;arginine-fifty homeobox pseudogene 2,-,-,-,-
5037,0,115,4,37,383,0,21,1,0,0,13,0,PEBP1;phosphatidylethanolamine binding protein 1,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010951//negative regulation of endopeptidase activity,GO:0008429//phosphatidylethanolamine binding;GO:0019901//protein kinase binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding,-
503834,0,0,0,0,0,0,0,0,2,0,0,0,DPRX;divergent-paired related homeobox,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
503835,0,0,0,0,0,0,0,0,50,0,0,0,DUXA;double homeobox A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
5042,0,0,0,0,2,0,34,0,27,0,0,0,"PABPC3;poly(A) binding protein, cytoplasmic 3",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0016071//mRNA metabolic process,GO:0008143//poly(A) binding;GO:0000166//nucleotide binding,K13126//RNA transport;mRNA surveillance pathway;RNA degradation
5045,0,0,1,0,13,1,0,78,75,0,0,0,FURIN;furin (paired basic amino acid cleaving enzyme),GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0030140//trans-Golgi network transport vesicle;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0045121//membrane raft;GO:0005802//trans-Golgi network,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0019058//viral life cycle;GO:0032455//nerve growth factor processing;GO:0030198//extracellular matrix organization;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016486//peptide hormone processing;GO:0032904//negative regulation of nerve growth factor production;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0019082//viral protein processing;GO:0008283//cell proliferation;GO:0052548//regulation of endopeptidase activity;GO:0032902//nerve growth factor production;GO:0007219//Notch signaling pathway;GO:0043687//post-translational protein modification;GO:0016032//viral process;GO:0032940//secretion by cell;GO:0032911//negative regulation of transforming growth factor beta1 production;GO:0016485//protein processing;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0019068//virion assembly;GO:0043043//peptide biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0010951//negative regulation of endopeptidase activity;GO:0042176//regulation of protein catabolic process;GO:0006465//signal peptide processing;GO:0030574//collagen catabolic process;GO:0032804//negative regulation of low-density lipoprotein particle receptor catabolic process,GO:0004175//endopeptidase activity;GO:0002020//protease binding;GO:0042277//peptide binding;GO:0004252//serine-type endopeptidase activity;GO:0048406//nerve growth factor binding;GO:0046872//metal ion binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008233//peptidase activity,K01349//Influenza A
5046,0,29,0,0,0,18,0,67,52,49,4,0,PCSK6;proprotein convertase subtilisin/kexin type 6,GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0009986//cell surface;GO:0005796//Golgi lumen,"GO:0032940//secretion by cell;GO:0030510//regulation of BMP signaling pathway;GO:0016486//peptide hormone processing;GO:0016485//protein processing;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007354//zygotic determination of anterior/posterior axis, embryo;GO:0032455//nerve growth factor processing;GO:0032902//nerve growth factor production;GO:0007368//determination of left/right symmetry;GO:0009100//glycoprotein metabolic process;GO:0006508//proteolysis",GO:0004175//endopeptidase activity;GO:0008201//heparin binding;GO:0048406//nerve growth factor binding;GO:0004252//serine-type endopeptidase activity,-
5047,0,0,0,0,0,0,0,77,8,0,1,0,PAEP;progestagen-associated endometrial protein,GO:0005576//extracellular region,GO:0007275//multicellular organismal development;GO:0006810//transport,GO:0036094//small molecule binding,-
5048,0,99,2,63,301,0,35,0,8,0,1,0,"PAFAH1B1;platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)",GO:0005871//kinesin complex;GO:0005875//microtubule associated complex;GO:0031512//motile primary cilium;GO:0005938//cell cortex;GO:0030426//growth cone;GO:0031252//cell leading edge;GO:0000776//kinetochore;GO:0070062//extracellular vesicular exosome;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0031513//nonmotile primary cilium;GO:0000235//astral microtubule;GO:0031965//nuclear membrane;GO:0005813//centrosome;GO:0043025//neuronal cell body,GO:0021766//hippocampus development;GO:0045931//positive regulation of mitotic cell cycle;GO:0045773//positive regulation of axon extension;GO:0021895//cerebral cortex neuron differentiation;GO:0016042//lipid catabolic process;GO:0032319//regulation of Rho GTPase activity;GO:0007097//nuclear migration;GO:0019226//transmission of nerve impulse;GO:0048854//brain morphogenesis;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0008344//adult locomotory behavior;GO:0008090//retrograde axon cargo transport;GO:0031023//microtubule organizing center organization;GO:0009306//protein secretion;GO:0007017//microtubule-based process;GO:0047496//vesicle transport along microtubule;GO:0000226//microtubule cytoskeleton organization;GO:0051081//nuclear envelope disassembly;GO:0017145//stem cell division;GO:0001764//neuron migration;GO:0021987//cerebral cortex development;GO:0046469//platelet activating factor metabolic process;GO:0021819//layer formation in cerebral cortex;GO:0010977//negative regulation of neuron projection development;GO:0001667//ameboidal cell migration;GO:0007611//learning or memory;GO:0050885//neuromuscular process controlling balance;GO:0021540//corpus callosum morphogenesis;GO:0001675//acrosome assembly;GO:0030036//actin cytoskeleton organization;GO:0007067//mitotic nuclear division;GO:0007405//neuroblast proliferation;GO:0051660//establishment of centrosome localization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007268//synaptic transmission;GO:0046329//negative regulation of JNK cascade;GO:0036035//osteoclast development;GO:0000132//establishment of mitotic spindle orientation,GO:0043274//phospholipase binding;GO:0008017//microtubule binding;GO:0045502//dynein binding;GO:0034452//dynactin binding;GO:0051219//phosphoprotein binding;GO:0045505//dynein intermediate chain binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008201//heparin binding,K01062//Ether lipid metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
50484,0,101,1,41,144,0,31,0,16,0,0,0,RRM2B;ribonucleotide reductase M2 B (TP53 inducible),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0006979//response to oxidative stress;GO:0009186//deoxyribonucleoside diphosphate metabolic process;GO:0006264//mitochondrial DNA replication;GO:0015949//nucleobase-containing small molecule interconversion;GO:0009200//deoxyribonucleoside triphosphate metabolic process;GO:0003014//renal system process;GO:0006281//DNA repair;GO:0001822//kidney development;GO:0044281//small molecule metabolic process,"GO:0046872//metal ion binding;GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",K10808//Purine metabolism;Glutathione metabolism;p53 signaling pathway;Pyrimidine metabolism;Metabolic pathways
50485,14,24,2,25,44,0,22,0,6,0,8,0,"SMARCAL1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1",GO:0005634//nucleus;GO:0035861//site of double-strand break;GO:0005662//DNA replication factor A complex,GO:0006974//cellular response to DNA damage stimulus;GO:0031297//replication fork processing;GO:0000733//DNA strand renaturation;GO:0016568//chromatin modification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006259//DNA metabolic process;GO:0006200//ATP catabolic process,GO:0036310//annealing helicase activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity;GO:0005524//ATP binding,-
50486,0,0,0,7,0,0,24,0,0,0,0,0,G0S2;G0/G1 switch 2,GO:0005739//mitochondrion;GO:0005811//lipid particle,GO:0044255//cellular lipid metabolic process;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0044281//small molecule metabolic process;GO:0097191//extrinsic apoptotic signaling pathway,GO:0005515//protein binding,-
50487,0,0,0,0,0,0,0,15,12,129,0,0,"PLA2G3;phospholipase A2, group III",GO:0005615//extracellular space;GO:0042629//mast cell granule;GO:0005814//centriole;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0060271//cilium morphogenesis;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0043303//mast cell degranulation;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0019372//lipoxygenase pathway;GO:0001675//acrosome assembly;GO:0007288//sperm axoneme assembly;GO:0016042//lipid catabolic process,GO:0005509//calcium ion binding;GO:0047498//calcium-dependent phospholipase A2 activity,K01047//Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;GnRH signaling pathway;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Metabolic pathways;Vascular smooth muscle contraction
50488,3,1,0,5,49,0,0,42,81,0,4,0,MINK1;misshapen-like kinase 1,GO:0045211//postsynaptic membrane;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030424//axon,GO:0007254//JNK cascade;GO:0045060//negative thymic T cell selection;GO:0035556//intracellular signal transduction;GO:0046330//positive regulation of JNK cascade;GO:0031532//actin cytoskeleton reorganization;GO:0001952//regulation of cell-matrix adhesion;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0048813//dendrite morphogenesis;GO:0022407//regulation of cell-cell adhesion;GO:0046777//protein autophosphorylation;GO:0030334//regulation of cell migration;GO:0050790//regulation of catalytic activity;GO:0006950//response to stress;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development,GO:0005524//ATP binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,-
50489,0,0,0,0,0,11,31,0,28,0,0,0,"CD207;CD207 molecule, langerin",GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0005886//plasma membrane,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0051607//defense response to virus;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I",GO:0030246//carbohydrate binding;GO:0005537//mannose binding,-
5049,0,85,0,12,206,21,20,4,1,0,0,0,"PAFAH1B2;platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0016239//positive regulation of macroautophagy;GO:0006629//lipid metabolic process;GO:0007420//brain development;GO:0007283//spermatogenesis;GO:0016042//lipid catabolic process,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity,K01062//Biosynthesis of secondary metabolites;Ether lipid metabolism;Metabolic pathways
5050,0,63,0,0,0,21,4,103,20,0,11,0,"PAFAH1B3;platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane,GO:0006629//lipid metabolic process;GO:0007399//nervous system development;GO:0016042//lipid catabolic process;GO:0007283//spermatogenesis;GO:0007420//brain development,GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
50506,25,0,0,0,0,35,16,51,36,0,19,0,DUOX2;dual oxidase 2,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0016324//apical plasma membrane,GO:0035264//multicellular organism growth;GO:0055114//oxidation-reduction process;GO:0042335//cuticle development;GO:0009566//fertilization;GO:0048855//adenohypophysis morphogenesis;GO:0030282//bone mineralization;GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0030878//thyroid gland development;GO:0042744//hydrogen peroxide catabolic process;GO:0051591//response to cAMP;GO:0042446//hormone biosynthetic process;GO:0006590//thyroid hormone generation;GO:0048839//inner ear development,GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0005509//calcium ion binding;GO:0016174//NAD(P)H oxidase activity,-
50507,0,0,0,0,0,12,0,0,0,0,0,0,NOX4;NADPH oxidase 4,GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0043020//NADPH oxidase complex,GO:0050667//homocysteine metabolic process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:2000573//positive regulation of DNA biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0014911//positive regulation of smooth muscle cell migration;GO:0072593//reactive oxygen species metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0071320//cellular response to cAMP;GO:0055114//oxidation-reduction process;GO:0042554//superoxide anion generation;GO:0055007//cardiac muscle cell differentiation;GO:0001666//response to hypoxia;GO:0007569//cell aging;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0000902//cell morphogenesis;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0071333//cellular response to glucose stimulus;GO:0071480//cellular response to gamma radiation;GO:0043065//positive regulation of apoptotic process;GO:0045453//bone resorption;GO:0051496//positive regulation of stress fiber assembly;GO:0006954//inflammatory response,GO:0072341//modified amino acid binding;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron carrier activity;GO:0019826//oxygen sensor activity;GO:0000166//nucleotide binding;GO:0020037//heme binding;GO:0016174//NAD(P)H oxidase activity;GO:0016175//superoxide-generating NADPH oxidase activity,K08008//Osteoclast differentiation;Phagosome;Leukocyte transendothelial migration
50508,0,0,0,0,0,0,0,0,2,0,0,0,NOX3;NADPH oxidase 3,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0043020//NADPH oxidase complex,GO:0042554//superoxide anion generation;GO:0055114//oxidation-reduction process;GO:0009590//detection of gravity;GO:0048840//otolith development;GO:0001659//temperature homeostasis,GO:0016175//superoxide-generating NADPH oxidase activity,K08008//Leukocyte transendothelial migration;Osteoclast differentiation;Phagosome
50509,45,0,0,0,0,55,149,39,116,1,18,284,"COL5A3;collagen, type V, alpha 3",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005588//collagen type V trimer;GO:0005788//endoplasmic reticulum lumen,GO:0007411//axon guidance;GO:0007160//cell-matrix adhesion;GO:0043588//skin development;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process,GO:0005201//extracellular matrix structural constituent;GO:0043394//proteoglycan binding;GO:0008201//heparin binding;GO:0005518//collagen binding,K06236//Focal adhesion;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction
5051,0,67,1,18,75,0,10,57,51,0,0,0,"PAFAH2;platelet-activating factor acetylhydrolase 2, 40kDa",GO:0005737//cytoplasm,GO:0006629//lipid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0016042//lipid catabolic process,GO:0005543//phospholipid binding;GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity,K01062//Metabolic pathways;Ether lipid metabolism;Biosynthesis of secondary metabolites
50511,0,0,0,0,0,0,29,0,0,0,0,0,SYCP3;synaptonemal complex protein 3,GO:0005694//chromosome;GO:0005634//nucleus,"GO:0035093//spermatogenesis, exchange of chromosomal proteins;GO:0007141//male meiosis I",GO:0003677//DNA binding,K06675//Cell cycle - yeast;K09187//Lysine degradation
50512,84,0,0,0,24,28,0,26,0,0,0,1,PODXL2;podocalyxin-like 2,GO:0005887//integral component of plasma membrane,GO:0050901//leukocyte tethering or rolling,GO:0005515//protein binding;GO:0005539//glycosaminoglycan binding,-
50514,0,0,0,0,0,0,8,0,0,0,0,0,DEC1;deleted in esophageal cancer 1,-,GO:0008285//negative regulation of cell proliferation,-,-
50515,0,0,0,0,0,1,0,58,19,0,0,0,CHST11;carbohydrate (chondroitin 4) sulfotransferase 11,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0043066//negative regulation of apoptotic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0016051//carbohydrate biosynthetic process;GO:0042733//embryonic digit morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0036342//post-anal tail morphogenesis;GO:0044281//small molecule metabolic process;GO:0007585//respiratory gaseous exchange;GO:0002063//chondrocyte development;GO:0048589//developmental growth;GO:0009791//post-embryonic development;GO:0033037//polysaccharide localization;GO:0030203//glycosaminoglycan metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0042127//regulation of cell proliferation,GO:0047756//chondroitin 4-sulfotransferase activity;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity;GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity,K01017//Sulfur metabolism;Glycosaminoglycan biosynthesis - chondroitin sulfate
5052,0,203,3,99,316,0,0,0,9,0,40,0,PRDX1;peroxiredoxin 1,GO:0005782//peroxisomal matrix;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005719//nuclear euchromatin;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome,GO:0032872//regulation of stress-activated MAPK cascade;GO:0034101//erythrocyte homeostasis;GO:0001501//skeletal system development;GO:0055114//oxidation-reduction process;GO:0008283//cell proliferation;GO:0001895//retina homeostasis;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0042744//hydrogen peroxide catabolic process;GO:0019430//removal of superoxide radicals;GO:0042267//natural killer cell mediated cytotoxicity,GO:0008379//thioredoxin peroxidase activity;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004601//peroxidase activity;GO:0020037//heme binding,K13279//Peroxisome
5053,0,0,0,6,0,0,0,0,34,195,7,0,PAH;phenylalanine hydroxylase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0042423//catecholamine biosynthetic process;GO:0042136//neurotransmitter biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0055114//oxidation-reduction process;GO:0008652//cellular amino acid biosynthetic process,GO:0016597//amino acid binding;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005506//iron ion binding,"K00500//Metabolic pathways;Phenylalanine, tyrosine and tryptophan biosynthesis;Phenylalanine metabolism"
5054,0,0,0,0,0,36,48,80,15,0,0,0,"SERPINE1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1",GO:0031012//extracellular matrix;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0030336//negative regulation of cell migration;GO:0010467//gene expression;GO:0001300//chronological cell aging;GO:0090026//positive regulation of monocyte chemotaxis;GO:0042730//fibrinolysis;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0035491//positive regulation of leukotriene production involved in inflammatory response;GO:0001525//angiogenesis;GO:0050829//defense response to Gram-negative bacterium;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030195//negative regulation of blood coagulation;GO:2000098//negative regulation of smooth muscle cell-matrix adhesion;GO:0032757//positive regulation of interleukin-8 production;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0050729//positive regulation of inflammatory response;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0010951//negative regulation of endopeptidase activity;GO:0071222//cellular response to lipopolysaccharide;GO:0030168//platelet activation;GO:0051918//negative regulation of fibrinolysis;GO:0042127//regulation of cell proliferation;GO:0030194//positive regulation of blood coagulation;GO:0061045//negative regulation of wound healing;GO:0014912//negative regulation of smooth muscle cell migration;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0010469//regulation of receptor activity;GO:0010757//negative regulation of plasminogen activation;GO:0045766//positive regulation of angiogenesis;GO:0030198//extracellular matrix organization;GO:0061044//negative regulation of vascular wound healing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0004867//serine-type endopeptidase inhibitor activity;GO:0002020//protease binding;GO:0005102//receptor binding;GO:0005515//protein binding,K03982//Chagas disease (American trypanosomiasis);p53 signaling pathway;Complement and coagulation cascades
5055,0,0,0,0,0,69,0,0,8,0,0,0,"SERPINB2;serpin peptidase inhibitor, clade B (ovalbumin), member 2",GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0007596//blood coagulation;GO:0030162//regulation of proteolysis;GO:0042730//fibrinolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0043066//negative regulation of apoptotic process,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5058,112,0,0,9,27,10,54,0,42,0,19,0,PAK1;p21 protein (Cdc42/Rac)-activated kinase 1,GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0031941//filamentous actin;GO:0005925//focal adhesion;GO:0030424//axon;GO:0030018//Z disc;GO:0043234//protein complex;GO:0031965//nuclear membrane;GO:0005911//cell-cell junction;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0014704//intercalated disc;GO:0030425//dendrite;GO:0005886//plasma membrane,GO:0006915//apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0001666//response to hypoxia;GO:0006887//exocytosis;GO:0006468//protein phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0051496//positive regulation of stress fiber assembly;GO:0016358//dendrite development;GO:0046777//protein autophosphorylation;GO:0000165//MAPK cascade;GO:0042060//wound healing;GO:0048754//branching morphogenesis of an epithelial tube;GO:0032869//cellular response to insulin stimulus;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0007411//axon guidance;GO:0031295//T cell costimulation;GO:0045087//innate immune response;GO:0043113//receptor clustering;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0048812//neuron projection morphogenesis;GO:0007528//neuromuscular junction development,GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005518//collagen binding;GO:0005524//ATP binding,K04409//Regulation of actin cytoskeleton;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Focal adhesion;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection;ErbB signaling pathway;Axon guidance;MAPK signaling pathway - yeast;Chemokine signaling pathway;Fc gamma R-mediated phagocytosis
506,0,99,2,48,220,0,20,0,22,51,0,0,"ATP5B;ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0005634//nucleus;GO:0005754//mitochondrial proton-transporting ATP synthase, catalytic core;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane",GO:0006091//generation of precursor metabolites and energy;GO:0015992//proton transport;GO:0051453//regulation of intracellular pH;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0022904//respiratory electron transport chain;GO:0006629//lipid metabolic process;GO:0006754//ATP biosynthetic process;GO:0001649//osteoblast differentiation;GO:0044237//cellular metabolic process;GO:0001525//angiogenesis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process,"GO:0042288//MHC class I protein binding;GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0022857//transmembrane transporter activity;GO:0005215//transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005515//protein binding",K02133//Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease;Metabolic pathways
50613,0,11,0,0,0,0,1,0,15,0,0,0,UBQLN3;ubiquilin 3,-,-,-,K04523//Protein processing in endoplasmic reticulum
50614,128,0,0,0,0,20,34,1,12,0,21,402,GALNT9;polypeptide N-acetylgalactosaminyltransferase 9,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0006493//protein O-linked glycosylation;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing,GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
50615,64,0,0,0,0,0,0,14,86,0,0,0,IL21R;interleukin 21 receptor,GO:0016021//integral component of membrane,GO:0030101//natural killer cell activation;GO:0038114//interleukin-21-mediated signaling pathway,GO:0001532//interleukin-21 receptor activity,K05075//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
50616,0,0,0,0,0,10,0,0,47,0,0,0,IL22;interleukin 22,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006953//acute-phase response;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0051384//response to glucocorticoid,GO:0005125//cytokine activity;GO:0045518//interleukin-22 receptor binding,K05445//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
50617,0,0,0,0,0,13,33,1,9,0,21,0,"ATP6V0A4;ATPase, H+ transporting, lysosomal V0 subunit a4","GO:0005768//endosome;GO:0031526//brush border membrane;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane;GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0045177//apical part of cell;GO:0016471//vacuolar proton-transporting V-type ATPase complex",GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006885//regulation of pH;GO:0001503//ossification;GO:0007605//sensory perception of sound;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0007588//excretion;GO:0015992//proton transport,GO:0051117//ATPase binding;GO:0005515//protein binding;GO:0015078//hydrogen ion transmembrane transporter activity,K02154//Tuberculosis;Synaptic vesicle cycle;Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Lysosome;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Oxidative phosphorylation;Metabolic pathways
50618,44,30,0,13,19,32,16,0,58,0,0,0,ITSN2;intersectin 2,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006897//endocytosis;GO:0032321//positive regulation of Rho GTPase activity;GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K07532//Tuberculosis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Axon guidance;K12331//Vascular smooth muscle contraction;K13738//Bacterial invasion of epithelial cells
50619,0,18,1,6,0,0,5,1,46,49,18,0,DEF6;differentially expressed in FDCP 6 homolog (mouse),GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
5062,47,173,1,31,246,20,15,27,52,0,13,0,PAK2;p21 protein (Cdc42/Rac)-activated kinase 2,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0031295//T cell costimulation;GO:0006469//negative regulation of protein kinase activity;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0040008//regulation of growth;GO:0007411//axon guidance;GO:0043066//negative regulation of apoptotic process;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0016310//phosphorylation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis;GO:0006915//apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0006468//protein phosphorylation,GO:0030296//protein tyrosine kinase activator activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity,K04410//Focal adhesion;Renal cell carcinoma;ErbB signaling pathway;Regulation of actin cytoskeleton;MAPK signaling pathway;Axon guidance;T cell receptor signaling pathway
50626,75,0,1,7,0,0,0,0,38,0,0,0,CYHR1;cysteine/histidine-rich 1,GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope,-,GO:0008270//zinc ion binding,K04506//Wnt signaling pathway;Ubiquitin mediated proteolysis;p53 signaling pathway
50628,0,0,1,0,10,0,11,98,16,0,34,0,GEMIN4;gem (nuclear organelle) associated protein 4,GO:0034719//SMN-Sm protein complex;GO:0016020//membrane;GO:0097504//Gemini of coiled bodies;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0032797//SMN complex;GO:0005737//cytoplasm;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0006364//rRNA processing;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0016070//RNA metabolic process;GO:0010467//gene expression,GO:0005515//protein binding,K13132//RNA transport
5063,196,0,0,0,0,9,0,0,42,0,0,0,PAK3;p21 protein (Cdc42/Rac)-activated kinase 3,GO:0005737//cytoplasm,GO:0007409//axonogenesis;GO:0016358//dendrite development;GO:0030833//regulation of actin filament polymerization;GO:0060997//dendritic spine morphogenesis;GO:0050808//synapse organization;GO:0006468//protein phosphorylation;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade,GO:0004674//protein serine/threonine kinase activity;GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004708//MAP kinase kinase activity;GO:0017048//Rho GTPase binding;GO:0005524//ATP binding,K05733//Renal cell carcinoma;Focal adhesion;ErbB signaling pathway;Regulation of actin cytoskeleton;T cell receptor signaling pathway;Axon guidance
50636,0,19,1,0,0,0,34,30,25,0,0,0,ANO7;anoctamin 7,GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0055085//transmembrane transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport,GO:0017128//phospholipid scramblase activity;GO:0005229//intracellular calcium activated chloride channel activity,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism
5064,0,0,0,0,0,0,22,0,5,0,0,2,PALM;paralemmin,GO:0032590//dendrite membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0030424//axon;GO:0016323//basolateral plasma membrane;GO:0016327//apicolateral plasma membrane;GO:0005886//plasma membrane;GO:0032591//dendritic spine membrane;GO:0031527//filopodium membrane;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0071257//cellular response to electrical stimulus;GO:0007194//negative regulation of adenylate cyclase activity;GO:0008360//regulation of cell shape;GO:0006928//cellular component movement;GO:0007010//cytoskeleton organization;GO:0072661//protein targeting to plasma membrane;GO:0051491//positive regulation of filopodium assembly;GO:0060999//positive regulation of dendritic spine development;GO:0060160//negative regulation of dopamine receptor signaling pathway;GO:0060074//synapse maturation,GO:0031750//D3 dopamine receptor binding;GO:0005515//protein binding,K06236//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption;Amoebiasis
50640,0,50,0,11,41,26,2,0,32,0,0,0,PNPLA8;patatin-like phospholipase domain containing 8,GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005777//peroxisome;GO:0005622//intracellular;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0006631//fatty acid metabolic process;GO:0046338//phosphatidylethanolamine catabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0019369//arachidonic acid metabolic process;GO:0043651//linoleic acid metabolic process;GO:0001516//prostaglandin biosynthetic process;GO:0044281//small molecule metabolic process;GO:0050482//arachidonic acid secretion;GO:0034638//phosphatidylcholine catabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0008219//cell death,GO:0047499//calcium-independent phospholipase A2 activity;GO:0005524//ATP binding;GO:0004622//lysophospholipase activity,K11447//Transcriptional misregulation in cancer;K01047//MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Metabolic pathways;Vascular smooth muscle contraction;GnRH signaling pathway;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;Toxoplasmosis;Arachidonic acid metabolism;Fat digestion and absorption;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism;Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
50649,0,0,0,0,0,0,45,0,61,0,10,0,ARHGEF4;Rho guanine nucleotide exchange factor (GEF) 4,GO:0032587//ruffle membrane;GO:0005829//cytosol,GO:0032855//positive regulation of Rac GTPase activity;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0030032//lamellipodium assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0046847//filopodium assembly;GO:0043547//positive regulation of GTPase activity,GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0019904//protein domain specific binding,K05769//Regulation of actin cytoskeleton
50650,0,60,0,13,67,8,2,0,26,145,6,0,ARHGEF3;Rho guanine nucleotide exchange factor (GEF) 3,GO:0005829//cytosol;GO:0005622//intracellular,GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K07532//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Axon guidance;Tuberculosis;K12330//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12331//Vascular smooth muscle contraction
50651,0,0,0,0,0,0,12,22,0,10,0,0,"SLC45A1;solute carrier family 45, member 1",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0008643//carbohydrate transport,GO:0015293//symporter activity,-
5066,0,1,0,0,1,39,69,48,0,0,2,0,PAM;peptidylglycine alpha-amidating monooxygenase,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005802//trans-Golgi network;GO:0030667//secretory granule membrane;GO:0005615//extracellular space;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm,GO:0051260//protein homooligomerization;GO:0060173//limb development;GO:0001519//peptide amidation;GO:0009268//response to pH;GO:0042493//response to drug;GO:0001676//long-chain fatty acid metabolic process;GO:0007507//heart development;GO:0051384//response to glucocorticoid;GO:0007417//central nervous system development;GO:0032956//regulation of actin cytoskeleton organization;GO:0007595//lactation;GO:0042476//odontogenesis;GO:0032355//response to estradiol;GO:0050708//regulation of protein secretion;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009404//toxin metabolic process;GO:0046688//response to copper ion;GO:0001666//response to hypoxia;GO:0022602//ovulation cycle process;GO:0055114//oxidation-reduction process;GO:0060135//maternal process involved in female pregnancy;GO:0018032//protein amidation,GO:0004598//peptidylamidoglycolate lyase activity;GO:0005507//copper ion binding;GO:0005509//calcium ion binding;GO:0004504//peptidylglycine monooxygenase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0031418//L-ascorbic acid binding;GO:0019901//protein kinase binding,-
5067,85,0,0,0,14,46,15,0,61,0,0,0,CNTN3;contactin 3 (plasmacytoma associated),GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0007399//nervous system development;GO:0007155//cell adhesion,-,-
50674,0,0,0,0,0,0,0,0,12,68,7,0,NEUROG3;neurogenin 3,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045666//positive regulation of neuron differentiation;GO:0031018//endocrine pancreas development;GO:0021510//spinal cord development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030902//hindbrain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030855//epithelial cell differentiation;GO:0030900//forebrain development;GO:0007399//nervous system development;GO:0007417//central nervous system development;GO:0060290//transdifferentiation;GO:0048814//regulation of dendrite morphogenesis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0007422//peripheral nervous system development;GO:0006351//transcription, DNA-templated",GO:0003690//double-stranded DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001047//core promoter binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0031490//chromatin DNA binding,K08028//Maturity onset diabetes of the young
5068,0,0,0,0,0,0,0,0,0,0,10,0,REG3A;regenerating islet-derived 3 alpha,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0090303//positive regulation of wound healing;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0010838//positive regulation of keratinocyte proliferation;GO:0006953//acute-phase response;GO:0045617//negative regulation of keratinocyte differentiation,GO:0030246//carbohydrate binding,K06560//Tuberculosis;Phagosome
5069,176,1,0,15,0,48,33,0,83,0,7,0,"PAPPA;pregnancy-associated plasma protein A, pappalysin 1",GO:0005576//extracellular region;GO:0016020//membrane;GO:0005615//extracellular space,GO:0030154//cell differentiation;GO:0032354//response to follicle-stimulating hormone;GO:0007565//female pregnancy;GO:0051384//response to glucocorticoid;GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis,GO:0004175//endopeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding,-
50700,79,0,0,0,0,0,0,0,14,55,0,0,RDH8;retinol dehydrogenase 8 (all-trans),GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0055114//oxidation-reduction process;GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light;GO:0042572//retinol metabolic process;GO:0006703//estrogen biosynthetic process;GO:0006694//steroid biosynthetic process;GO:0007601//visual perception",GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity,K11150//Metabolic pathways;Retinol metabolism
5071,0,0,0,0,16,10,54,0,38,0,9,0,PARK2;parkin RBR E3 ubiquitin protein ligase,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0071797//LUBAC complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005794//Golgi apparatus;GO:0043005//neuron projection;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0016235//aggresome;GO:0000151//ubiquitin ligase complex,"GO:0034976//response to endoplasmic reticulum stress;GO:0043524//negative regulation of neuron apoptotic process;GO:0008344//adult locomotory behavior;GO:0001964//startle response;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0070842//aggresome assembly;GO:0000422//mitochondrion degradation;GO:0060548//negative regulation of cell death;GO:0046676//negative regulation of insulin secretion;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0051865//protein autoubiquitination;GO:0010821//regulation of mitochondrion organization;GO:0010506//regulation of autophagy;GO:0042417//dopamine metabolic process;GO:0006351//transcription, DNA-templated;GO:0000209//protein polyubiquitination;GO:0001933//negative regulation of protein phosphorylation;GO:0044257//cellular protein catabolic process;GO:1901215//negative regulation of neuron death;GO:0007417//central nervous system development;GO:0006513//protein monoubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032232//negative regulation of actin filament bundle assembly;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:1902530//positive regulation of protein linear polyubiquitination;GO:0033132//negative regulation of glucokinase activity;GO:0070936//protein K48-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0046928//regulation of neurotransmitter secretion;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0042415//norepinephrine metabolic process;GO:0008219//cell death;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035249//synaptic transmission, glutamatergic;GO:0071287//cellular response to manganese ion;GO:0016567//protein ubiquitination;GO:0007612//learning;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0014059//regulation of dopamine secretion;GO:0097237//cellular response to toxic substance",GO:0061630//ubiquitin protein ligase activity;GO:0031072//heat shock protein binding;GO:0001664//G-protein coupled receptor binding;GO:0019900//kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043130//ubiquitin binding;GO:1990381//ubiquitin-specific protease binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding;GO:0016874//ligase activity;GO:0051087//chaperone binding;GO:0031624//ubiquitin conjugating enzyme binding,K04556//Protein processing in endoplasmic reticulum;Parkinson's disease;Ubiquitin mediated proteolysis
50717,0,71,1,72,135,34,24,40,29,0,20,0,DCAF8;DDB1 and CUL4 associated factor 8,GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
5073,153,28,0,16,22,7,0,0,68,194,21,0,PARN;poly(A)-specific ribonuclease,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol,"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0009451//RNA modification;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0007292//female gamete generation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016071//mRNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0016070//RNA metabolic process",GO:0004535//poly(A)-specific ribonuclease activity;GO:0019901//protein kinase binding;GO:0003730//mRNA 3'-UTR binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0004518//nuclease activity,K01148//RNA degradation
5074,0,24,17,0,11,0,0,49,4,0,0,0,"PAWR;PRKC, apoptosis, WT1, regulator",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005884//actin filament,"GO:0042130//negative regulation of T cell proliferation;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0042094//interleukin-2 biosynthetic process;GO:0030889//negative regulation of B cell proliferation;GO:0051017//actin filament bundle assembly;GO:0050860//negative regulation of T cell receptor signaling pathway",GO:0003714//transcription corepressor activity;GO:0003779//actin binding;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0043522//leucine zipper domain binding,K06270//Focal adhesion;Long-term potentiation;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
5075,0,0,0,0,0,41,16,0,5,0,30,0,PAX1;paired box 1,GO:0005634//nucleus,"GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0060349//bone morphogenesis;GO:0061056//sclerotome development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048538//thymus development;GO:0060017//parathyroid gland development;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0001756//somitogenesis",GO:0003677//DNA binding,-
5076,1,0,0,0,0,0,0,61,0,0,0,0,PAX2;paired box 2,GO:0034451//centriolar satellite;GO:0032993//protein-DNA complex;GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0005764//lysosome;GO:0005634//nucleus,"GO:0071300//cellular response to retinoic acid;GO:0035566//regulation of metanephros size;GO:0071333//cellular response to glucose stimulus;GO:0048793//pronephros development;GO:0007568//aging;GO:0001843//neural tube closure;GO:0090103//cochlea morphogenesis;GO:0061205//paramesonephric duct development;GO:0001823//mesonephros development;GO:0006351//transcription, DNA-templated;GO:0035799//ureter maturation;GO:0048854//brain morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0021554//optic nerve development;GO:0043491//protein kinase B signaling;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0072179//nephric duct formation;GO:0043069//negative regulation of programmed cell death;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development;GO:0072593//reactive oxygen species metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0055114//oxidation-reduction process;GO:0090102//cochlea development;GO:0021631//optic nerve morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061360//optic chiasma development;GO:0001655//urogenital system development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0070301//cellular response to hydrogen peroxide;GO:0060231//mesenchymal to epithelial transition;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031016//pancreas development;GO:0072189//ureter development;GO:0072075//metanephric mesenchyme development;GO:0007409//axonogenesis;GO:0048863//stem cell differentiation;GO:0031667//response to nutrient levels;GO:0045918//negative regulation of cytolysis;GO:0001709//cell fate determination;GO:0002072//optic cup morphogenesis involved in camera-type eye development;GO:2000594//positive regulation of metanephric DCT cell differentiation;GO:0072289//metanephric nephron tubule formation;GO:0007601//visual perception;GO:0072207//metanephric epithelium development;GO:2000597//positive regulation of optic nerve formation;GO:0007501//mesodermal cell fate specification;GO:0039003//pronephric field specification;GO:1900218//negative regulation of apoptotic process involved in metanephric nephron tubule development;GO:0021633//optic nerve structural organization;GO:0072197//ureter morphogenesis;GO:0072172//mesonephric tubule formation;GO:0043066//negative regulation of apoptotic process;GO:0042472//inner ear morphogenesis;GO:0072205//metanephric collecting duct development;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043010//camera-type eye development;GO:1900215//negative regulation of apoptotic process involved in metanephric collecting duct development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0072305//negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis;GO:0071260//cellular response to mechanical stimulus;GO:0072177//mesonephric duct development;GO:0072221//metanephric distal convoluted tubule development;GO:0072300//positive regulation of metanephric glomerulus development;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0010001//glial cell differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0021650//vestibulocochlear nerve formation;GO:0072162//metanephric mesenchymal cell differentiation;GO:0003406//retinal pigment epithelium development;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0070742//C2H2 zinc finger domain binding;GO:0005515//protein binding;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding,-
5077,0,0,0,0,0,27,0,6,54,0,6,0,PAX3;paired box 3,GO:0005634//nucleus,"GO:0007517//muscle organ development;GO:0001755//neural crest cell migration;GO:0021527//spinal cord association neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006915//apoptotic process;GO:0001843//neural tube closure;GO:0014807//regulation of somitogenesis;GO:0048066//developmental pigmentation;GO:0048663//neuron fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0060594//mammary gland specification;GO:0007507//heart development;GO:0007605//sensory perception of sound;GO:0008284//positive regulation of cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0071837//HMG box domain binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,K09381//Transcriptional misregulation in cancer
5078,94,0,0,0,0,0,0,0,21,0,0,0,PAX4;paired box 4,GO:0005654//nucleoplasm,"GO:0051591//response to cAMP;GO:0031018//endocrine pancreas development;GO:0060041//retina development in camera-type eye;GO:0030154//cell differentiation;GO:0042493//response to drug;GO:0045597//positive regulation of cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007623//circadian rhythm;GO:0043066//negative regulation of apoptotic process;GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0003677//DNA binding,K08032//Maturity onset diabetes of the young
5079,229,0,0,0,0,16,5,61,54,0,8,1,PAX5;paired box 5,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0007399//nervous system development;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006959//humoral immune response;GO:0006366//transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K09383//Transcriptional misregulation in cancer
5080,188,54,0,17,26,8,0,0,56,0,29,0,PAX6;paired box 6,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm,"GO:0030902//hindbrain development;GO:0007224//smoothened signaling pathway;GO:0060041//retina development in camera-type eye;GO:0048596//embryonic camera-type eye morphogenesis;GO:0030334//regulation of cell migration;GO:0009611//response to wounding;GO:0007601//visual perception;GO:0042462//eye photoreceptor cell development;GO:0021918//regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment;GO:0001709//cell fate determination;GO:0021905//forebrain-midbrain boundary formation;GO:0061072//iris morphogenesis;GO:0021902//commitment of neuronal cell to specific neuron type in forebrain;GO:0001764//neuron migration;GO:0007435//salivary gland morphogenesis;GO:0021797//forebrain anterior/posterior pattern specification;GO:0048505//regulation of timing of cell differentiation;GO:0042593//glucose homeostasis;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0030858//positive regulation of epithelial cell differentiation;GO:0002088//lens development in camera-type eye;GO:0001568//blood vessel development;GO:0001654//eye development;GO:0061303//cornea development in camera-type eye;GO:0021796//cerebral cortex regionalization;GO:0010628//positive regulation of gene expression;GO:0007417//central nervous system development;GO:0048708//astrocyte differentiation;GO:0021912//regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification;GO:0002052//positive regulation of neuroblast proliferation;GO:0032808//lacrimal gland development;GO:0009887//organ morphogenesis;GO:0048663//neuron fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003322//pancreatic A cell development;GO:0042660//positive regulation of cell fate specification;GO:0050680//negative regulation of epithelial cell proliferation;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0030216//keratinocyte differentiation;GO:0050768//negative regulation of neurogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0009950//dorsal/ventral axis specification;GO:0033365//protein localization to organelle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0003309//type B pancreatic cell differentiation;GO:0021778//oligodendrocyte cell fate specification;GO:0021983//pituitary gland development;GO:0045665//negative regulation of neuron differentiation;GO:0007411//axon guidance;GO:0016567//protein ubiquitination;GO:0023019//signal transduction involved in regulation of gene expression",GO:0035035//histone acetyltransferase binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0031625//ubiquitin protein ligase binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003690//double-stranded DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0070412//R-SMAD binding;GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0071837//HMG box domain binding;GO:0003680//AT DNA binding;GO:0019901//protein kinase binding;GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0070410//co-SMAD binding;GO:0008134//transcription factor binding,K08031//Maturity onset diabetes of the young
50801,85,0,0,0,0,11,0,0,0,0,24,1,"KCNK4;potassium channel, subfamily K, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0006813//potassium ion transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,-
50804,0,0,0,0,10,0,0,0,0,0,0,0,MYEF2;myelin expression factor 2,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0014902//myotube differentiation",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003677//DNA binding,K12887//Spliceosome
50805,0,0,0,9,0,0,0,0,15,0,22,0,IRX4;iroquois homeobox 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0048561//establishment of organ orientation;GO:0007507//heart development",GO:0043565//sequence-specific DNA binding,K15610//Transcriptional misregulation in cancer;K15613//Transcriptional misregulation in cancer;K09355//Transcriptional misregulation in cancer
50807,0,0,0,0,15,26,36,0,16,0,0,0,"ASAP1;ArfGAP with SH3 domain, ankyrin repeat and PH domain 1",GO:0016020//membrane;GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity;GO:0060271//cilium morphogenesis,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0008060//ARF GTPase activator activity",K12488//Endocytosis;Fc gamma R-mediated phagocytosis
50808,29,17,0,20,160,20,9,0,53,0,10,0,AK3;adenylate kinase 3,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0016310//phosphorylation;GO:0046033//AMP metabolic process;GO:0046051//UTP metabolic process;GO:0046039//GTP metabolic process;GO:0007596//blood coagulation;GO:0046041//ITP metabolic process;GO:0006172//ADP biosynthetic process,GO:0004017//adenylate kinase activity;GO:0046899//nucleoside triphosphate adenylate kinase activity;GO:0005524//ATP binding;GO:0005525//GTP binding,K00944//Pyrimidine metabolism
50809,0,70,9,75,256,16,0,0,11,0,0,0,"HP1BP3;heterochromatin protein 1, binding protein 3",GO:0005634//nucleus;GO:0005730//nucleolus;GO:0000786//nucleosome,GO:0006334//nucleosome assembly,GO:0003677//DNA binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
5081,0,20,0,0,13,8,70,0,0,0,0,0,PAX7;paired box 7,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling;GO:0021527//spinal cord association neuron differentiation;GO:0043393//regulation of protein binding;GO:0048706//embryonic skeletal system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048663//neuron fate commitment;GO:0060415//muscle tissue morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0031062//positive regulation of histone methylation;GO:0043066//negative regulation of apoptotic process;GO:2000288//positive regulation of myoblast proliferation;GO:0014813//skeletal muscle satellite cell commitment;GO:0043403//skeletal muscle tissue regeneration;GO:0010453//regulation of cell fate commitment;GO:0021904//dorsal/ventral neural tube patterning;GO:0051216//cartilage development,GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity,K09381//Transcriptional misregulation in cancer
50810,0,0,0,8,50,0,0,0,48,0,0,0,"HDGFRP3;hepatoma-derived growth factor, related protein 3",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008283//cell proliferation,GO:0008083//growth factor activity,"K00020//Pentose phosphate pathway;Valine, leucine and isoleucine degradation;Metabolic pathways;Glutathione metabolism"
50813,0,0,1,5,16,10,35,8,14,59,16,43,COPS7A;COP9 signalosome subunit 7A,GO:0008180//COP9 signalosome;GO:0005737//cytoplasm,GO:0010388//cullin deneddylation,-,-
50814,88,0,1,0,4,0,1,0,17,0,0,1,NSDHL;NAD(P) dependent steroid dehydrogenase-like,GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0005789//endoplasmic reticulum membrane,GO:0001942//hair follicle development;GO:0060716//labyrinthine layer blood vessel development;GO:0007224//smoothened signaling pathway;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process,GO:0047012//sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity;GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity,K07748//Metabolic pathways;Steroid biosynthesis
5082,0,0,0,35,4,0,0,59,24,0,0,0,PDCL;phosducin-like,GO:0005737//cytoplasm,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0006457//protein folding;GO:0061084//negative regulation of protein refolding;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0035556//intracellular signal transduction,GO:0005057//receptor signaling protein activity;GO:0032403//protein complex binding,K08327//Olfactory transduction
5083,0,1,0,0,23,0,0,0,46,0,0,0,PAX9;paired box 9,GO:0005634//nucleus,"GO:0042481//regulation of odontogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042476//odontogenesis;GO:0071363//cellular response to growth factor stimulus;GO:0007492//endoderm development;GO:0060325//face morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
50831,0,0,0,0,0,0,0,0,28,0,0,0,"TAS2R3;taste receptor, type 2, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050909//sensory perception of taste;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction,GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50832,0,0,0,0,0,0,40,0,15,0,0,0,"TAS2R4;taste receptor, type 2, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0060170//ciliary membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0050909//sensory perception of taste;GO:0007585//respiratory gaseous exchange,GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50833,0,0,0,0,0,1,0,0,0,0,0,0,"TAS2R16;taste receptor, type 2, member 16",GO:0005802//trans-Golgi network;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0005515//protein binding;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50834,0,0,0,0,0,0,1,0,12,0,0,0,"TAS2R1;taste receptor, type 2, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007635//chemosensory behavior;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50835,0,0,0,0,0,0,0,0,0,0,5,0,"TAS2R9;taste receptor, type 2, member 9",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050912//detection of chemical stimulus involved in sensory perception of taste,GO:0008527//taste receptor activity,K08474//Taste transduction
50838,0,0,0,0,0,0,53,0,0,0,0,0,"TAS2R13;taste receptor, type 2, member 13",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0032467//positive regulation of cytokinesis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50839,0,0,0,0,0,0,0,0,16,0,0,0,"TAS2R10;taste receptor, type 2, member 10",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008527//taste receptor activity;GO:0033038//bitter taste receptor activity,K08474//Taste transduction
50846,0,0,48,1,0,0,15,7,8,2,0,0,DHH;desert hedgehog,GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0006508//proteolysis;GO:0042552//myelination;GO:0030238//male sex determination;GO:0033327//Leydig cell differentiation;GO:0032355//response to estradiol;GO:0007286//spermatid development;GO:0050810//regulation of steroid biosynthetic process;GO:0007267//cell-cell signaling,GO:0008233//peptidase activity;GO:0005515//protein binding;GO:0005113//patched binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding,K11990//Hedgehog signaling pathway
50848,0,0,0,0,1,0,57,0,23,0,0,0,F11R;F11 receptor,GO:0005923//tight junction;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005911//cell-cell junction;GO:0015630//microtubule cytoskeleton,GO:0030198//extracellular matrix organization;GO:0006954//inflammatory response;GO:0016032//viral process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0050900//leukocyte migration;GO:0045216//cell-cell junction organization;GO:0070830//tight junction assembly;GO:0007596//blood coagulation;GO:0034329//cell junction assembly;GO:0007155//cell adhesion;GO:0030855//epithelial cell differentiation,GO:0005515//protein binding,K06089//Cell adhesion molecules (CAMs);Tight junction;Epithelial cell signaling in Helicobacter pylori infection;Leukocyte transendothelial migration
50853,87,1,0,1,0,0,24,0,63,0,0,0,VILL;villin-like,GO:0015629//actin cytoskeleton,GO:0051693//actin filament capping;GO:0007010//cytoskeleton organization,GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton,-
50854,0,0,0,0,2,0,0,0,1,0,0,0,C6orf48;chromosome 6 open reading frame 48,-,-,-,-
50855,0,0,1,0,0,0,0,0,12,0,8,0,PARD6A;par-6 family cell polarity regulator alpha,GO:0005923//tight junction;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0001726//ruffle;GO:0005938//cell cortex;GO:0043234//protein complex;GO:0045177//apical part of cell,GO:0034329//cell junction assembly;GO:0045217//cell-cell junction maintenance;GO:0016032//viral process;GO:0051301//cell division;GO:0070830//tight junction assembly;GO:0045216//cell-cell junction organization;GO:0007049//cell cycle;GO:0007179//transforming growth factor beta receptor signaling pathway,GO:0005080//protein kinase C binding;GO:0008134//transcription factor binding;GO:0017048//Rho GTPase binding;GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding,K06093//Tight junction;Endocytosis
50856,0,0,0,0,0,0,0,0,16,0,5,0,"CLEC4A;C-type lectin domain family 4, member A",GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0045087//innate immune response;GO:0007166//cell surface receptor signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding,-
50859,0,0,0,0,0,8,13,0,15,0,0,0,"SPOCK3;sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space,GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0007165//signal transduction;GO:0010951//negative regulation of endopeptidase activity,GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0005539//glycosaminoglycan binding,-
50861,0,0,0,0,0,15,24,0,9,0,5,0,STMN3;stathmin-like 3,GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0030424//axon;GO:0005794//Golgi apparatus,GO:0035021//negative regulation of Rac protein signal transduction;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0051493//regulation of cytoskeleton organization;GO:0007399//nervous system development;GO:0032314//regulation of Rac GTPase activity;GO:0031122//cytoplasmic microtubule organization;GO:0031175//neuron projection development,GO:0019904//protein domain specific binding;GO:0015631//tubulin binding,K04381//MAPK signaling pathway
50862,0,86,1,77,328,0,9,0,26,0,0,0,RNF141;ring finger protein 141,-,"GO:0051865//protein autoubiquitination;GO:0006355//regulation of transcription, DNA-templated",GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
50863,0,0,48,0,0,0,0,1,38,79,0,0,NTM;neurotrimin,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0008038//neuron recognition;GO:0007155//cell adhesion,GO:0005515//protein binding,-
50865,0,0,0,9,51,0,0,0,3,0,0,0,HEBP1;heme binding protein 1,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0007623//circadian rhythm,GO:0020037//heme binding,-
5087,0,47,0,41,203,0,11,0,37,0,0,0,PBX1;pre-B-cell leukemia homeobox 1,GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0030278//regulation of ossification;GO:0035162//embryonic hemopoiesis;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0009954//proximal/distal pattern formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0048706//embryonic skeletal system development;GO:0007548//sex differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045665//negative regulation of neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0009887//organ morphogenesis;GO:0030325//adrenal gland development;GO:0030326//embryonic limb morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0048538//thymus development;GO:0048536//spleen development;GO:0006694//steroid biosynthetic process",GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K09355//Transcriptional misregulation in cancer
509,0,77,0,17,36,0,0,0,66,0,0,0,"ATP5C1;ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1","GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);GO:0070062//extracellular vesicular exosome;GO:0005759//mitochondrial matrix;GO:0005753//mitochondrial proton-transporting ATP synthase complex",GO:0022904//respiratory electron transport chain;GO:0006119//oxidative phosphorylation;GO:0006754//ATP biosynthetic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process,"GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0016887//ATPase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0044822//poly(A) RNA binding;GO:0022857//transmembrane transporter activity",K02136//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
5090,0,0,0,24,14,28,0,0,0,0,0,0,PBX3;pre-B-cell leukemia homeobox 3,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0021516//dorsal spinal cord development;GO:0006351//transcription, DNA-templated;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0007388//posterior compartment specification;GO:0048666//neuron development;GO:0006355//regulation of transcription, DNA-templated;GO:0007387//anterior compartment pattern formation;GO:0007585//respiratory gaseous exchange;GO:0008344//adult locomotory behavior",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09355//Transcriptional misregulation in cancer;K15610//Transcriptional misregulation in cancer
5091,0,0,0,13,0,40,0,1,50,0,0,0,PC;pyruvate carboxylase,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0006768//biotin metabolic process;GO:0006766//vitamin metabolic process;GO:0006094//gluconeogenesis;GO:0006629//lipid metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0009374//biotin binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004736//pyruvate carboxylase activity;GO:0005524//ATP binding;GO:0004075//biotin carboxylase activity,K01958//Citrate cycle (TCA cycle);Metabolic pathways;Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Pyruvate metabolism
5092,0,37,0,46,56,0,0,0,0,0,2,0,PCBD1;pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006559//L-phenylalanine catabolic process;GO:0051289//protein homotetramerization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0006351//transcription, DNA-templated;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0051291//protein heterooligomerization;GO:0043496//regulation of protein homodimerization activity",GO:0003713//transcription coactivator activity;GO:0008124//4-alpha-hydroxytetrahydrobiopterin dehydratase activity;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0005515//protein binding;GO:0042802//identical protein binding,-
5093,199,0,0,13,30,0,1,0,15,0,9,0,PCBP1;poly(rC) binding protein 1,GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K12889//Spliceosome
50937,54,22,11,0,0,7,34,0,18,0,0,0,"CDON;cell adhesion associated, oncogene regulated",GO:0031012//extracellular matrix;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0051149//positive regulation of muscle cell differentiation;GO:0001708//cell fate specification;GO:0043410//positive regulation of MAPK cascade;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0002088//lens development in camera-type eye;GO:0010172//embryonic body morphogenesis;GO:0007224//smoothened signaling pathway;GO:0043497//regulation of protein heterodimerization activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:0045666//positive regulation of neuron differentiation;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0042692//muscle cell differentiation;GO:0014816//skeletal muscle satellite cell differentiation;GO:0007520//myoblast fusion;GO:0021987//cerebral cortex development;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion,GO:0005515//protein binding,-
50939,0,0,0,0,0,76,19,0,61,133,0,0,IMPG2;interphotoreceptor matrix proteoglycan 2,GO:0005578//proteinaceous extracellular matrix;GO:0043235//receptor complex;GO:0016021//integral component of membrane,GO:0007601//visual perception,GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding;GO:0005540//hyaluronic acid binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
5094,0,73,3,147,670,0,40,0,2,2,3,0,PCBP2;poly(rC) binding protein 2,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032480//negative regulation of type I interferon production;GO:0016071//mRNA metabolic process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0050687//negative regulation of defense response to virus;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0003723//RNA binding;GO:0019899//enzyme binding,-
50940,99,24,0,69,209,39,0,0,29,15,5,0,PDE11A;phosphodiesterase 11A,GO:0043204//perikaryon;GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0007165//signal transduction;GO:0046069//cGMP catabolic process;GO:0006198//cAMP catabolic process,"GO:0046872//metal ion binding;GO:0030552//cAMP binding;GO:0030553//cGMP binding;GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity",K13298//Morphine addiction;Purine metabolism
50943,0,84,0,106,142,8,0,0,18,0,208,0,FOXP3;forkhead box P3,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0042110//T cell activation;GO:0008285//negative regulation of cell proliferation;GO:0009615//response to virus;GO:0035067//negative regulation of histone acetylation;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0035066//positive regulation of histone acetylation;GO:0031064//negative regulation of histone deacetylation;GO:0032693//negative regulation of interleukin-10 production;GO:0032689//negative regulation of interferon-gamma production;GO:0002456//T cell mediated immunity;GO:0043029//T cell homeostasis;GO:0002262//myeloid cell homeostasis;GO:0002677//negative regulation of chronic inflammatory response;GO:0046007//negative regulation of activated T cell proliferation;GO:0032703//negative regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway;GO:0001816//cytokine production;GO:0033092//positive regulation of immature T cell proliferation in thymus;GO:0006338//chromatin remodeling;GO:0002851//positive regulation of peripheral T cell tolerance induction;GO:0032720//negative regulation of tumor necrosis factor production;GO:0042130//negative regulation of T cell proliferation;GO:0002669//positive regulation of T cell anergy;GO:0032792//negative regulation of CREB transcription factor activity;GO:0002725//negative regulation of T cell cytokine production;GO:0032713//negative regulation of interleukin-4 production;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042036//negative regulation of cytokine biosynthetic process;GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0006355//regulation of transcription, DNA-templated;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0032753//positive regulation of interleukin-4 production;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050710//negative regulation of cytokine secretion;GO:0002513//tolerance induction to self antigen;GO:0001782//B cell homeostasis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032714//negative regulation of interleukin-5 production;GO:0006366//transcription from RNA polymerase II promoter;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0050777//negative regulation of immune response;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0032715//negative regulation of interleukin-6 production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032831//positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0035035//histone acetyltransferase binding;GO:0051525//NFAT protein binding;GO:0051059//NF-kappaB binding;GO:0003714//transcription corepressor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
50944,97,0,0,0,7,49,28,0,69,103,5,0,SHANK1;SH3 and multiple ankyrin repeat domains 1,GO:0060076//excitatory synapse;GO:0005622//intracellular;GO:0017146//N-methyl-D-aspartate selective glutamate receptor complex;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0016020//membrane;GO:0045211//postsynaptic membrane;GO:0097481//neuronal postsynaptic density;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0008328//ionotropic glutamate receptor complex,GO:0046959//habituation;GO:0035176//social behavior;GO:0030534//adult behavior;GO:0032232//negative regulation of actin filament bundle assembly;GO:0060074//synapse maturation;GO:0007616//long-term memory;GO:0060997//dendritic spine morphogenesis;GO:0042048//olfactory behavior;GO:0050885//neuromuscular process controlling balance;GO:0008306//associative learning;GO:0035418//protein localization to synapse;GO:0060013//righting reflex;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0071625//vocalization behavior;GO:0006461//protein complex assembly;GO:0050894//determination of affect;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0060999//positive regulation of dendritic spine development,GO:0032403//protein complex binding;GO:0017124//SH3 domain binding;GO:0030160//GKAP/Homer scaffold activity;GO:0042802//identical protein binding;GO:0008022//protein C-terminus binding;GO:0097110//scaffold protein binding;GO:0071532//ankyrin repeat binding;GO:0035255//ionotropic glutamate receptor binding;GO:0005515//protein binding,K15009//Glutamatergic synapse
50945,2,0,0,0,0,23,0,0,44,0,0,0,TBX22;T-box 22,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
5095,73,0,0,67,43,1,0,0,52,0,12,0,"PCCA;propionyl CoA carboxylase, alpha polypeptide",GO:0005759//mitochondrial matrix;GO:0005829//cytosol,GO:0006768//biotin metabolic process;GO:0006766//vitamin metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019626//short-chain fatty acid catabolic process;GO:0006635//fatty acid beta-oxidation;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0046872//metal ion binding;GO:0009374//biotin binding;GO:0004658//propionyl-CoA carboxylase activity;GO:0019899//enzyme binding;GO:0004075//biotin carboxylase activity;GO:0005524//ATP binding,"K01965//Metabolic pathways;Valine, leucine and isoleucine degradation;Propanoate metabolism;Microbial metabolism in diverse environments;Glyoxylate and dicarboxylate metabolism"
5096,0,39,0,39,43,0,0,72,81,0,0,0,"PCCB;propionyl CoA carboxylase, beta polypeptide",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0019626//short-chain fatty acid catabolic process;GO:0044255//cellular lipid metabolic process;GO:0006766//vitamin metabolic process;GO:0006768//biotin metabolic process,GO:0004658//propionyl-CoA carboxylase activity;GO:0005524//ATP binding,"K01966//Nitrogen metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Propanoate metabolism;Microbial metabolism in diverse environments;Glyoxylate and dicarboxylate metabolism"
50964,0,0,0,0,0,0,0,0,37,0,10,0,SOST;sclerostin,GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,"GO:0016055//Wnt signaling pathway;GO:2000054//negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0030514//negative regulation of BMP signaling pathway;GO:0001503//ossification;GO:0030279//negative regulation of ossification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0009612//response to mechanical stimulus;GO:0031333//negative regulation of protein complex assembly",GO:0008201//heparin binding;GO:0005515//protein binding;GO:0008134//transcription factor binding,-
5097,0,0,0,0,6,14,38,0,30,89,0,0,PCDH1;protocadherin 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development;GO:0007267//cell-cell signaling,GO:0005509//calcium ion binding,-
5098,0,0,0,0,0,0,9,0,25,0,0,0,"PCDHGC3;protocadherin gamma subfamily C, 3",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0005509//calcium ion binding,-
5099,0,0,0,0,0,68,50,124,47,0,1,0,PCDH7;protocadherin 7,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
50999,147,0,0,4,20,96,14,33,50,339,49,0,TMED5;transmembrane emp24 protein transport domain containing 5,GO:0070971//endoplasmic reticulum exit site;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane,GO:0015031//protein transport;GO:0090161//Golgi ribbon formation,GO:0005515//protein binding,-
51,0,636,154,419,763,4,41,530,136,52,525,0,"ACOX1;acyl-CoA oxidase 1, palmitoyl",GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005778//peroxisomal membrane,GO:0016559//peroxisome fission;GO:0044281//small molecule metabolic process;GO:0006693//prostaglandin metabolic process;GO:0055088//lipid homeostasis;GO:2000189//positive regulation of cholesterol homeostasis;GO:0044255//cellular lipid metabolic process;GO:0019395//fatty acid oxidation;GO:0000038//very long-chain fatty acid metabolic process;GO:0006629//lipid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0036109//alpha-linolenic acid metabolic process;GO:0007283//spermatogenesis;GO:0006091//generation of precursor metabolites and energy,GO:0016401//palmitoyl-CoA oxidase activity;GO:0003997//acyl-CoA oxidase activity;GO:0071949//FAD binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0047485//protein N-terminus binding;GO:0030165//PDZ domain binding;GO:0005504//fatty acid binding;GO:0050660//flavin adenine dinucleotide binding;GO:0005102//receptor binding,"K00232//PPAR signaling pathway;alpha-Linolenic acid metabolism;Peroxisome;Propanoate metabolism;beta-Alanine metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;Biosynthesis of unsaturated fatty acids;Fatty acid metabolism"
5100,0,0,0,0,0,0,23,1,5,0,8,0,PCDH8;protocadherin 8,GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0045211//postsynaptic membrane;GO:0005887//integral component of plasma membrane,GO:0007268//synaptic transmission;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001756//somitogenesis;GO:0016331//morphogenesis of embryonic epithelium;GO:0007267//cell-cell signaling,GO:0005509//calcium ion binding,-
51000,0,0,0,5,20,13,0,0,7,0,0,0,"SLC35B3;solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005739//mitochondrion,GO:0055085//transmembrane transport;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process,-,-
51001,0,0,0,9,2,0,0,0,33,89,0,0,MTERF3;mitochondrial transcription termination factor 3,GO:0005739//mitochondrion,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding,-
51003,0,55,30,100,91,0,0,0,17,0,60,0,MED31;mediator complex subunit 31,GO:0005654//nucleoplasm;GO:0016592//mediator complex,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0060173//limb development;GO:0006461//protein complex assembly;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0048147//negative regulation of fibroblast proliferation,GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity,-
51004,0,24,65,16,37,21,53,86,39,0,108,0,COQ6;coenzyme Q6 monooxygenase,GO:0042995//cell projection;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus,GO:0006744//ubiquinone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process,"GO:0050660//flavin adenine dinucleotide binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",K06126//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
51005,0,0,0,0,30,0,48,193,0,0,57,0,AMDHD2;amidohydrolase domain containing 2,GO:0005634//nucleus,GO:0006044//N-acetylglucosamine metabolic process;GO:0005975//carbohydrate metabolic process;GO:0019262//N-acetylneuraminate catabolic process,GO:0046872//metal ion binding;GO:0008448//N-acetylglucosamine-6-phosphate deacetylase activity,K01443//Metabolic pathways;ABC transporters;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Ribosome;Riboflavin metabolism
51006,180,0,0,0,7,14,0,1,36,0,0,0,"SLC35C2;solute carrier family 35 (GDP-fucose transporter), member C2",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane,GO:0036066//protein O-linked fucosylation;GO:0045747//positive regulation of Notch signaling pathway;GO:0006810//transport;GO:0010629//negative regulation of gene expression,-,-
51008,0,706,264,433,1148,0,61,174,54,62,532,1,ASCC1;activating signal cointegrator 1 complex subunit 1,GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003824//catalytic activity;GO:0003723//RNA binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K09057//Circadian rhythm - fly;K12756//Leukocyte transendothelial migration;Focal adhesion;Tight junction;Regulation of actin cytoskeleton;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
51009,0,1,0,0,16,0,0,0,45,0,8,0,DERL2;derlin 2,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005770//late endosome;GO:0005769//early endosome,"GO:0001967//suckling behavior;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030970//retrograde protein transport, ER to cytosol;GO:0008284//positive regulation of cell proliferation;GO:0030307//positive regulation of cell growth",GO:0005515//protein binding,K13989//Protein processing in endoplasmic reticulum
5101,0,0,0,0,0,0,0,0,47,0,0,0,PCDH9;protocadherin 9,GO:0044291//cell-cell contact zone;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030426//growth cone,GO:0030900//forebrain development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
51010,0,0,0,0,59,0,0,14,8,167,0,0,EXOSC3;exosome component 3,GO:0035327//transcriptionally active chromatin;GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex);GO:0000177//cytoplasmic exosome (RNase complex);GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000176//nuclear exosome (RNase complex),"GO:0006364//rRNA processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0016070//RNA metabolic process;GO:0045190//isotype switching;GO:0016071//mRNA metabolic process;GO:0071034//CUT catabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0045006//DNA deamination;GO:0010467//gene expression;GO:0045830//positive regulation of isotype switching;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0004532//exoribonuclease activity;GO:0003723//RNA binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0005515//protein binding,K03681//RNA degradation
51011,0,0,0,0,17,0,49,37,5,0,0,0,FAHD2A;fumarylacetoacetate hydrolase domain containing 2A,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K01557//Tyrosine metabolism;Metabolic pathways
51012,0,21,0,17,71,0,0,0,16,0,0,0,SLMO2;slowmo homolog 2 (Drosophila),GO:0005758//mitochondrial intermembrane space,GO:0015914//phospholipid transport,GO:1990050//phosphatidic acid transporter activity,-
51013,0,0,0,6,3,33,0,0,0,0,1,0,EXOSC1;exosome component 1,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000178//exosome (RNase complex),"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0006364//rRNA processing",GO:0004532//exoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding,K07573//RNA degradation
51014,0,0,0,0,5,0,0,0,0,0,0,0,TMED7;transmembrane emp24 protein transport domain containing 7,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0030126//COPI vesicle coat;GO:0005789//endoplasmic reticulum membrane;GO:0030127//COPII vesicle coat,GO:0015031//protein transport,-,-
51015,0,16,0,14,78,0,0,0,6,0,6,0,ISOC1;isochorismatase domain containing 1,GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0003824//catalytic activity,K04432//Toxoplasmosis;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Epstein-Barr virus infection;GnRH signaling pathway;Fc epsilon RI signaling pathway;Influenza A;Toll-like receptor signaling pathway
51016,11,15,40,0,2,0,0,3,9,120,7,0,EMC9;ER membrane protein complex subunit 9,GO:0072546//ER membrane protein complex;GO:0005737//cytoplasm,-,-,-
51018,0,0,0,7,1,26,0,0,44,39,0,0,RRP15;ribosomal RNA processing 15 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
51020,0,0,0,0,0,0,0,0,40,0,0,0,HDDC2;HD domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,-,GO:0005515//protein binding,-
51021,0,54,29,26,9,4,52,0,0,0,0,0,MRPS16;mitochondrial ribosomal protein S16,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;Metabolic pathways;beta-Alanine metabolism
51022,0,26,0,18,14,0,0,0,0,0,0,242,GLRX2;glutaredoxin 2,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0010033//response to organic substance;GO:0042262//DNA protection;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006457//protein folding;GO:0055114//oxidation-reduction process;GO:0006749//glutathione metabolic process;GO:0009966//regulation of signal transduction;GO:0009266//response to temperature stimulus;GO:0045454//cell redox homeostasis;GO:0051775//response to redox state;GO:0042542//response to hydrogen peroxide","GO:0003756//protein disulfide isomerase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0009055//electron carrier activity;GO:0008794//arsenate reductase (glutaredoxin) activity;GO:0046872//metal ion binding;GO:0015038//glutathione disulfide oxidoreductase activity;GO:0051537//2 iron, 2 sulfur cluster binding",K03676//Pyrimidine metabolism;Purine metabolism;Metabolic pathways
51023,0,0,1,0,28,0,0,0,0,0,0,0,MRPS18C;mitochondrial ribosomal protein S18C,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K10600//Ubiquitin mediated proteolysis
51024,0,2,0,34,64,0,0,0,8,0,1,0,FIS1;fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae),GO:0031307//integral component of mitochondrial outer membrane;GO:0005777//peroxisome;GO:0043234//protein complex;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0010821//regulation of mitochondrion organization;GO:0090314//positive regulation of protein targeting to membrane;GO:0051260//protein homooligomerization;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0070584//mitochondrion morphogenesis;GO:0000266//mitochondrial fission;GO:0016559//peroxisome fission;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0090141//positive regulation of mitochondrial fission;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0008053//mitochondrial fusion;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0001836//release of cytochrome c from mitochondria;GO:0006626//protein targeting to mitochondrion;GO:0000422//mitochondrion degradation,GO:0005515//protein binding;GO:0005102//receptor binding,K15044//Influenza A
51025,0,0,0,0,1,0,0,0,0,0,0,0,PAM16;presequence translocase-associated motor 16 homolog (S. cerevisiae),GO:0005744//mitochondrial inner membrane presequence translocase complex,GO:0030150//protein import into mitochondrial matrix;GO:0006626//protein targeting to mitochondrion;GO:0044267//cellular protein metabolic process,-,-
51026,28,0,2,0,11,15,35,0,7,0,0,0,GOLT1B;golgi transport 1B,GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0016192//vesicle-mediated transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction;GO:0015031//protein transport,GO:0004871//signal transducer activity,K00923//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
51027,0,0,0,0,0,0,0,0,10,0,0,0,BOLA1;bolA family member 1,GO:0005739//mitochondrion;GO:0005576//extracellular region,-,-,-
51028,0,22,0,30,74,25,0,59,26,41,0,0,VPS36;vacuolar protein sorting 36 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005764//lysosome;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005770//late endosome;GO:0016020//membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0006351//transcription, DNA-templated",GO:0043130//ubiquitin binding;GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding,K12190//Endocytosis
51029,0,0,0,0,12,0,0,0,0,0,0,0,DESI2;desumoylating isopeptidase 2,GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0008233//peptidase activity,-
51030,106,0,30,18,19,0,0,0,0,0,0,0,TVP23B;trans-golgi network vesicle protein 23 homolog B (S. cerevisiae),GO:0016021//integral component of membrane,-,-,-
51031,0,1,1,14,67,0,0,0,21,0,21,0,GLOD4;glyoxalase domain containing 4,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,-,-,-
51032,50,0,0,7,39,0,0,0,18,0,0,0,"CELA2B;chymotrypsin-like elastase family, member 2B",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K01346//Pancreatic secretion;Protein digestion and absorption
51035,0,1,0,0,7,0,0,1,19,0,0,0,UBXN1;UBX domain protein 1,GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0034098//Cdc48p-Npl4p-Ufd1p AAA ATPase complex;GO:0030425//dendrite,GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031397//negative regulation of protein ubiquitination,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0031593//polyubiquitin binding;GO:0051117//ATPase binding;GO:0071796//K6-linked polyubiquitin binding;GO:0043130//ubiquitin binding,-
5104,4,0,0,0,0,0,47,0,30,0,0,0,"SERPINA5;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5",GO:0036025//protein C inhibitor-TMPRSS11E complex;GO:0097181//protein C inhibitor-coagulation factor V complex;GO:0036028//protein C inhibitor-thrombin complex;GO:0036027//protein C inhibitor-PLAU complex;GO:0031091//platelet alpha granule;GO:0031094//platelet dense tubular network;GO:0005615//extracellular space;GO:0097182//protein C inhibitor-coagulation factor Xa complex;GO:0036024//protein C inhibitor-TMPRSS7 complex;GO:0002080//acrosomal membrane;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0036029//protein C inhibitor-KLK3 complex;GO:0036030//protein C inhibitor-plasma kallikrein complex;GO:0097183//protein C inhibitor-coagulation factor XI complex;GO:0043234//protein complex;GO:0036026//protein C inhibitor-PLAT complex,GO:0006869//lipid transport;GO:0007283//spermatogenesis;GO:0045861//negative regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis;GO:0007342//fusion of sperm to egg plasma membrane,GO:0001972//retinoic acid binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0031210//phosphatidylcholine binding;GO:0002020//protease binding;GO:0005539//glycosaminoglycan binding;GO:0032190//acrosin binding;GO:0008201//heparin binding,K03913//Complement and coagulation cascades
51042,0,0,0,0,1,20,0,0,0,0,0,0,ZNF593;zinc finger protein 593,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
51043,0,48,0,0,20,13,23,1,17,0,19,1,ZBTB7B;zinc finger and BTB domain containing 7B,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007398//ectoderm development;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
51046,62,0,0,0,0,11,46,0,59,0,15,0,"ST8SIA3;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3",GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane,GO:0009311//oligosaccharide metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0097503//sialylation;GO:0009100//glycoprotein metabolic process;GO:0044267//cellular protein metabolic process;GO:0001574//ganglioside biosynthetic process;GO:0006688//glycosphingolipid biosynthetic process,"GO:0033691//sialic acid binding;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",-
5105,0,0,0,0,0,0,29,0,26,0,9,128,PCK1;phosphoenolpyruvate carboxykinase 1 (soluble),GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0014823//response to activity;GO:0017144//drug metabolic process;GO:0006094//gluconeogenesis;GO:0044281//small molecule metabolic process;GO:0032868//response to insulin;GO:0046327//glycerol biosynthetic process from pyruvate;GO:0006006//glucose metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0006475//internal protein amino acid acetylation;GO:0005975//carbohydrate metabolic process;GO:0042593//glucose homeostasis,GO:0031406//carboxylic acid binding;GO:0005525//GTP binding;GO:0000287//magnesium ion binding;GO:0030145//manganese ion binding;GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity;GO:0019003//GDP binding,K01596//Proximal tubule bicarbonate reclamation;Citrate cycle (TCA cycle);Metabolic pathways;Pyruvate metabolism;Adipocytokine signaling pathway;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Insulin signaling pathway;Microbial metabolism in diverse environments;PPAR signaling pathway
51050,0,0,1,60,135,0,14,0,48,0,0,0,PI15;peptidase inhibitor 15,GO:0070062//extracellular vesicular exosome,GO:0010466//negative regulation of peptidase activity,GO:0030414//peptidase inhibitor activity,-
51052,0,0,0,0,0,0,0,0,0,0,24,0,PRLH;prolactin releasing hormone,GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0006112//energy reserve metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045444//fat cell differentiation;GO:0009749//response to glucose;GO:0001894//tissue homeostasis;GO:0006629//lipid metabolic process;GO:0032868//response to insulin;GO:0002023//reduction of food intake in response to dietary excess;GO:0048483//autonomic nervous system development,GO:0031861//prolactin-releasing peptide receptor binding;GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity,-
51053,0,0,0,6,39,1,27,0,0,0,0,0,"GMNN;geminin, DNA replication inhibitor",GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008156//negative regulation of DNA replication;GO:0009887//organ morphogenesis;GO:0000278//mitotic cell cycle;GO:0006461//protein complex assembly;GO:0045786//negative regulation of cell cycle;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0070491//repressing transcription factor binding,-
51056,23,1,0,37,50,0,0,0,0,0,0,0,LAP3;leucine aminopeptidase 3,GO:0005802//trans-Golgi network;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0008235//metalloexopeptidase activity;GO:0004177//aminopeptidase activity;GO:0030145//manganese ion binding,K11142//Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways
51057,97,0,0,0,0,0,2,0,41,0,0,0,WDPCP;WD repeat containing planar cell polarity effector,GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0016324//apical plasma membrane;GO:0005930//axoneme,GO:2000114//regulation of establishment of cell polarity;GO:0042384//cilium assembly;GO:0045184//establishment of protein localization;GO:0051893//regulation of focal adhesion assembly;GO:0016476//regulation of embryonic cell shape;GO:1900027//regulation of ruffle assembly;GO:0007224//smoothened signaling pathway;GO:0032185//septin cytoskeleton organization;GO:0060021//palate development;GO:0055123//digestive system development;GO:0042733//embryonic digit morphogenesis;GO:0001822//kidney development;GO:0043010//camera-type eye development;GO:0002093//auditory receptor cell morphogenesis;GO:0032880//regulation of protein localization;GO:0010762//regulation of fibroblast migration;GO:0072358//cardiovascular system development;GO:0060541//respiratory system development;GO:0060271//cilium morphogenesis,-,-
51058,9,0,0,0,0,0,0,0,11,0,0,0,ZNF691;zinc finger protein 691,GO:0005634//nucleus,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
51059,0,0,0,0,1,0,18,0,65,0,14,0,"FAM135B;family with sequence similarity 135, member B",-,-,-,-
5106,0,0,0,0,0,18,0,21,78,0,2,0,PCK2;phosphoenolpyruvate carboxykinase 2 (mitochondrial),GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006116//NADH oxidation;GO:0006094//gluconeogenesis;GO:0071333//cellular response to glucose stimulus;GO:0005975//carbohydrate metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0006107//oxaloacetate metabolic process;GO:0051384//response to glucocorticoid;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process,GO:0005525//GTP binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004613//phosphoenolpyruvate carboxykinase (GTP) activity,K01596//Proximal tubule bicarbonate reclamation;Adipocytokine signaling pathway;Pyruvate metabolism;Citrate cycle (TCA cycle);Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;PPAR signaling pathway;Microbial metabolism in diverse environments;Insulin signaling pathway
51060,0,0,0,15,8,0,0,0,68,0,6,0,TXNDC12;thioredoxin domain containing 12 (endoplasmic reticulum),GO:0005788//endoplasmic reticulum lumen,GO:0055114//oxidation-reduction process;GO:0045454//cell redox homeostasis,GO:0019153//protein-disulfide reductase (glutathione) activity,K05360//Glutathione metabolism
51061,0,0,0,15,89,19,0,0,22,0,0,0,TXNDC11;thioredoxin domain containing 11,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0045454//cell redox homeostasis;GO:0006457//protein folding;GO:0034976//response to endoplasmic reticulum stress,GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding,K09582//Protein processing in endoplasmic reticulum;Vibrio cholerae infection;K08056//Protein processing in endoplasmic reticulum;Antigen processing and presentation
51062,0,0,17,8,70,0,0,0,11,0,0,0,ATL1;atlastin GTPase 1,GO:0005789//endoplasmic reticulum membrane;GO:0000137//Golgi cis cisterna;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0030424//axon,GO:0008219//cell death;GO:0007029//endoplasmic reticulum organization;GO:0051260//protein homooligomerization;GO:0006184//GTP catabolic process;GO:0007409//axonogenesis,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
51063,98,0,0,0,8,0,0,0,15,0,18,1,CALHM2;calcium homeostasis modulator 2,GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
51065,0,1,0,28,127,32,0,0,20,0,7,0,RPS27L;ribosomal protein S27-like,GO:0005634//nucleus;GO:0005840//ribosome,GO:0006974//cellular response to DNA damage stimulus;GO:0045727//positive regulation of translation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006412//translation;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006281//DNA repair,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome;GO:0008494//translation activator activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process,K02978//Ribosome
51066,0,0,0,0,11,0,0,2,0,0,11,0,SSUH2;ssu-2 homolog (C. elegans),GO:0005737//cytoplasm,-,-,-
51067,0,1,0,11,32,0,0,0,33,0,9,0,"YARS2;tyrosyl-tRNA synthetase 2, mitochondrial",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006412//translation;GO:0070184//mitochondrial tyrosyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0000049//tRNA binding;GO:0005524//ATP binding;GO:0072545//tyrosine binding;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0004831//tyrosine-tRNA ligase activity,K01866//Aminoacyl-tRNA biosynthesis;ABC transporters;Peptidoglycan biosynthesis
51068,0,29,1,45,48,18,0,0,0,0,5,0,NMD3;NMD3 ribosome export adaptor,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016020//membrane,GO:0000055//ribosomal large subunit export from nucleus;GO:0015031//protein transport,"GO:0043023//ribosomal large subunit binding;GO:0044822//poly(A) RNA binding;GO:0030674//protein binding, bridging",K07562//Ribosome biogenesis in eukaryotes;RNA transport
51070,0,1,0,0,18,20,0,0,0,0,0,0,NOSIP;nitric oxide synthase interacting protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000139//Golgi membrane;GO:0005829//cytosol,GO:0043086//negative regulation of catalytic activity;GO:0050999//regulation of nitric-oxide synthase activity;GO:0044281//small molecule metabolic process;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0046209//nitric oxide metabolic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
51071,0,0,0,0,1,0,0,0,7,0,0,0,DERA;deoxyribose-phosphate aldolase (putative),GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0009264//deoxyribonucleotide catabolic process;GO:0046121//deoxyribonucleoside catabolic process;GO:0046386//deoxyribose phosphate catabolic process,GO:0004139//deoxyribose-phosphate aldolase activity,K01619//Pentose phosphate pathway
51073,61,1,0,0,0,0,0,0,8,0,0,0,MRPL4;mitochondrial ribosomal protein L4,GO:0005840//ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
51074,0,22,0,76,130,0,37,0,15,0,0,0,APIP;APAF1 interacting protein,GO:0005829//cytosol,GO:0006595//polyamine metabolic process;GO:0019284//L-methionine biosynthetic process from S-adenosylmethionine;GO:0044281//small molecule metabolic process;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process,GO:0008270//zinc ion binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0046570//methylthioribulose 1-phosphate dehydratase activity,K08964//Cysteine and methionine metabolism;Metabolic pathways
51075,0,16,0,27,41,0,0,0,21,0,0,0,TMX2;thioredoxin-related transmembrane protein 2,GO:0016021//integral component of membrane,GO:0045454//cell redox homeostasis,-,K03671//Pyrimidine metabolism;Selenocompound metabolism
51076,0,0,0,16,10,0,0,1,1,0,0,0,CUTC;cutC copper transporter,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051262//protein tetramerization;GO:0055070//copper ion homeostasis;GO:0006825//copper ion transport,GO:0005507//copper ion binding,-
51077,0,0,0,24,51,0,0,0,20,0,0,0,FCF1;FCF1 rRNA-processing protein,GO:0005730//nucleolus;GO:0032040//small-subunit processome,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,K14566//Ribosome biogenesis in eukaryotes
51078,0,0,3,24,0,0,0,1,11,0,0,0,THAP4;THAP domain containing 4,-,-,GO:0003677//DNA binding;GO:0046872//metal ion binding,K00943//One carbon pool by folate;Metabolic pathways;Two-component system;Pyrimidine metabolism
51079,0,16,3,16,26,0,0,0,0,0,0,0,"NDUFA13;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005746//mitochondrial respiratory chain,"GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0044237//cellular metabolic process;GO:0035458//cellular response to interferon-beta;GO:0022904//respiratory electron transport chain;GO:0045039//protein import into mitochondrial inner membrane;GO:0010952//positive regulation of peptidase activity;GO:0097190//apoptotic signaling pathway;GO:0030308//negative regulation of cell growth;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0071300//cellular response to retinoic acid;GO:0045892//negative regulation of transcription, DNA-templated;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway",GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0005524//ATP binding;GO:0003954//NADH dehydrogenase activity;GO:0005515//protein binding,K11353//Metabolic pathways;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease
5108,47,75,1,81,208,0,46,73,56,202,0,0,PCM1;pericentriolar material 1,GO:0000242//pericentriolar material;GO:0034451//centriolar satellite;GO:0005829//cytosol;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0043234//protein complex;GO:0031513//nonmotile primary cilium;GO:0031965//nuclear membrane,GO:0050768//negative regulation of neurogenesis;GO:0090316//positive regulation of intracellular protein transport;GO:0097150//neuronal stem cell maintenance;GO:0031122//cytoplasmic microtubule organization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0051297//centrosome organization;GO:0042384//cilium assembly;GO:0034454//microtubule anchoring at centrosome;GO:0022027//interkinetic nuclear migration;GO:0071539//protein localization to centrosome;GO:0035735//intraciliary transport involved in cilium morphogenesis;GO:0034453//microtubule anchoring,GO:0042802//identical protein binding;GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
51081,0,0,0,65,75,1,0,136,0,0,76,0,MRPS7;mitochondrial ribosomal protein S7,GO:0022627//cytosolic small ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
51082,0,58,20,14,39,2,0,53,10,213,0,0,"POLR1D;polymerase (RNA) I polypeptide D, 16kDa",GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005829//cytosol,GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter,GO:0046983//protein dimerization activity;GO:0001054//RNA polymerase I activity;GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding,K03020//Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Pyrimidine metabolism;Cytosolic DNA-sensing pathway;Metabolic pathways
51083,0,0,0,0,0,0,0,0,11,0,0,0,GAL;galanin/GMAP prepropeptide,GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule,GO:0019933//cAMP-mediated signaling;GO:1902891//negative regulation of root hair elongation;GO:0050672//negative regulation of lymphocyte proliferation;GO:0007218//neuropeptide signaling pathway;GO:0032868//response to insulin;GO:0042493//response to drug;GO:0031943//regulation of glucocorticoid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0043627//response to estrogen;GO:0007399//nervous system development;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity;GO:0007631//feeding behavior;GO:0010737//protein kinase A signaling;GO:0051795//positive regulation of catagen;GO:0051464//positive regulation of cortisol secretion;GO:0030073//insulin secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response,GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding,-
51084,5,95,11,1,39,13,0,57,9,0,1,444,"CRYL1;crystallin, lambda 1",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0055114//oxidation-reduction process;GO:0006631//fatty acid metabolic process,GO:0070403//NAD+ binding;GO:0042803//protein homodimerization activity;GO:0050104//L-gulonate 3-dehydrogenase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity,K13247//Metabolic pathways;Pentose and glucuronate interconversions
51085,1,0,0,1,0,13,0,0,18,0,0,398,MLXIPL;MLX interacting protein-like,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000505//regulation of energy homeostasis;GO:0070328//triglyceride homeostasis;GO:0006112//energy reserve metabolic process;GO:0055089//fatty acid homeostasis;GO:0046889//positive regulation of lipid biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010255//glucose mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0042593//glucose homeostasis;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0031325//positive regulation of cellular metabolic process;GO:0090324//negative regulation of oxidative phosphorylation;GO:0045821//positive regulation of glycolytic process;GO:0035556//intracellular signal transduction;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0071157//negative regulation of cell cycle arrest;GO:0042304//regulation of fatty acid biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0035538//carbohydrate response element binding,-
51087,0,0,0,0,0,0,0,0,22,0,4,0,YBX2;Y box binding protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005844//polysome,"GO:0051100//negative regulation of binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0007286//spermatid development;GO:0009386//translational attenuation;GO:0048255//mRNA stabilization;GO:0048599//oocyte development;GO:0006355//regulation of transcription, DNA-templated;GO:0017148//negative regulation of translation",GO:0008289//lipid binding;GO:0045182//translation regulator activity;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0003730//mRNA 3'-UTR binding,-
51088,0,0,0,0,13,57,0,19,13,0,0,0,KLHL5;kelch-like family member 5,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,GO:0003779//actin binding,-
51090,0,0,0,0,7,0,0,0,0,0,0,0,PLLP;plasmolipin,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0043218//compact myelin,GO:0009611//response to wounding;GO:0042552//myelination;GO:0006811//ion transport,-,-
51091,0,0,0,0,4,7,0,0,33,0,14,0,SEPSECS;Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process;GO:0001514//selenocysteine incorporation,"GO:0005515//protein binding;GO:0030170//pyridoxal phosphate binding;GO:0016785//transferase activity, transferring selenium-containing groups;GO:0000049//tRNA binding",K03341//Selenocompound metabolism;Aminoacyl-tRNA biosynthesis
51092,0,0,47,13,7,0,0,12,14,0,19,585,"SIDT2;SID1 transmembrane family, member 2",GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0009749//response to glucose;GO:0000902//cell morphogenesis;GO:0003323//type B pancreatic cell development;GO:0042593//glucose homeostasis;GO:0044342//type B pancreatic cell proliferation;GO:0033227//dsRNA transport,GO:0051033//RNA transmembrane transporter activity,-
51093,0,50,56,41,24,0,32,27,22,0,119,1,RRNAD1;ribosomal RNA adenine dimethylase domain containing 1,GO:0016021//integral component of membrane,GO:0031167//rRNA methylation,"GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity",-
51094,64,22,0,2,54,0,0,0,51,0,6,0,ADIPOR1;adiponectin receptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0019395//fatty acid oxidation;GO:0033211//adiponectin-activated signaling pathway;GO:0009755//hormone-mediated signaling pathway;GO:0030308//negative regulation of cell growth;GO:0046427//positive regulation of JAK-STAT cascade;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0033210//leptin-mediated signaling pathway,GO:0046982//protein heterodimerization activity;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0004872//receptor activity;GO:0055100//adiponectin binding;GO:0042562//hormone binding,K07297//Adipocytokine signaling pathway
51095,0,0,2,14,93,45,0,0,0,0,0,0,"TRNT1;tRNA nucleotidyl transferase, CCA-adding, 1",GO:0005622//intracellular;GO:0005739//mitochondrion,GO:0006626//protein targeting to mitochondrion;GO:0001680//tRNA 3'-terminal CCA addition;GO:0042780//tRNA 3'-end processing,GO:0052928//CTP:3'-cytidine-tRNA cytidylyltransferase activity;GO:0004810//tRNA adenylyltransferase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0052929//ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity;GO:0052927//CTP:tRNA cytidylyltransferase activity,K00974//RNA transport
51096,0,25,1,8,13,2,0,41,16,0,22,0,UTP18;UTP18 small subunit (SSU) processome component homolog (yeast),GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,K14553//Ribosome biogenesis in eukaryotes
51097,0,2,1,38,73,13,0,12,32,0,3,0,SCCPDH;saccharopine dehydrogenase (putative),GO:0005634//nucleus;GO:0030496//midbody;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005811//lipid particle,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
51098,0,0,0,0,13,36,0,0,48,0,8,0,IFT52;intraflagellar transport 52,GO:0097546//ciliary base;GO:0005929//cilium;GO:0005814//centriole;GO:0031514//motile cilium;GO:0044292//dendrite terminus;GO:0030992//intraciliary transport particle B;GO:0032391//photoreceptor connecting cilium,GO:0060271//cilium morphogenesis;GO:0007224//smoothened signaling pathway;GO:0042073//intraciliary transport;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070613//regulation of protein processing;GO:0042733//embryonic digit morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0001947//heart looping;GO:0001841//neural tube formation,GO:0008022//protein C-terminus binding,-
51099,0,26,0,0,32,0,0,0,11,0,11,0,ABHD5;abhydrolase domain containing 5,GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005811//lipid particle;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051006//positive regulation of lipoprotein lipase activity;GO:0044281//small molecule metabolic process;GO:0030154//cell differentiation;GO:0019433//triglyceride catabolic process;GO:0006631//fatty acid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0010891//negative regulation of sequestering of triglyceride;GO:0010898//positive regulation of triglyceride catabolic process,GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0004806//triglyceride lipase activity,-
5110,0,42,0,7,13,37,0,0,5,0,0,0,PCMT1;protein-L-isoaspartate (D-aspartate) O-methyltransferase,GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0006479//protein methylation;GO:0030091//protein repair,GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,-
51100,269,37,0,10,56,14,0,0,108,0,0,0,SH3GLB1;SH3-domain GRB2-like endophilin B1,GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0043234//protein complex;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0051084//'de novo' posttranslational protein folding;GO:0032461//positive regulation of protein oligomerization;GO:0051259//protein oligomerization;GO:0006654//phosphatidic acid biosynthetic process,GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0042171//lysophosphatidic acid acyltransferase activity;GO:0005504//fatty acid binding,K11248//Endocytosis
51101,0,0,12,0,27,17,0,0,0,0,0,0,"ZC2HC1A;zinc finger, C2HC-type containing 1A",-,-,GO:0046872//metal ion binding,-
51102,0,0,0,1,0,0,0,0,5,0,20,0,MECR;mitochondrial trans-2-enoyl-CoA reductase,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process;GO:0006631//fatty acid metabolic process,GO:0008270//zinc ion binding;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity,K07512//Fatty acid elongation;Metabolic pathways
51103,0,0,0,1,0,17,0,0,0,0,0,0,"NDUFAF1;NADH dehydrogenase (ubiquinone) complex I, assembly factor 1",GO:0005747//mitochondrial respiratory chain complex I;GO:0005737//cytoplasm,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006461//protein complex assembly",GO:0051082//unfolded protein binding;GO:0005515//protein binding,K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
51104,0,1,0,9,8,0,0,0,39,181,0,0,ABHD17B;abhydrolase domain containing 17B,GO:0016020//membrane;GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
51105,0,28,0,45,45,41,0,0,19,0,0,0,PHF20L1;PHD finger protein 20-like 1,-,-,GO:0005515//protein binding;GO:0008270//zinc ion binding,K06101//Tight junction;Lysine degradation;K09189//Lysine degradation
51106,0,0,0,4,15,0,0,0,23,0,0,0,"TFB1M;transcription factor B1, mitochondrial",GO:0042645//mitochondrial nucleoid,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0031167//rRNA methylation","GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0005515//protein binding",-
51107,0,1,0,22,73,0,2,0,22,0,0,0,APH1A;APH1A gamma secretase subunit,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0032580//Golgi cisterna membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0006509//membrane protein ectodomain proteolysis;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0031293//membrane protein intracellular domain proteolysis;GO:0007220//Notch receptor processing;GO:0016485//protein processing;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0001656//metanephros development,GO:0004175//endopeptidase activity;GO:0005515//protein binding,K06172//Notch signaling pathway;Alzheimer's disease
51108,0,59,1,39,188,15,2,0,16,0,0,0,METTL9;methyltransferase like 9,-,-,GO:0005515//protein binding,-
51109,0,1,52,81,138,0,0,0,10,0,1,0,RDH11;retinol dehydrogenase 11 (all-trans/9-cis/11-cis),GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0001917//photoreceptor inner segment,"GO:0016062//adaptation of rhodopsin mediated signaling;GO:0042574//retinal metabolic process;GO:0001523//retinoid metabolic process;GO:0055114//oxidation-reduction process;GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light",GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity,K11152//Metabolic pathways;Retinol metabolism
5111,0,17,0,1,109,0,17,1,0,0,0,0,PCNA;proliferating cell nuclear antigen,GO:0005634//nucleus;GO:0005663//DNA replication factor C complex;GO:0005730//nucleolus;GO:0070557//PCNA-p21 complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0043596//nuclear replication fork;GO:0043626//PCNA complex,"GO:0046686//response to cadmium ion;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0033993//response to lipid;GO:0008283//cell proliferation;GO:0032077//positive regulation of deoxyribonuclease activity;GO:0006272//leading strand elongation;GO:0019985//translesion synthesis;GO:0007507//heart development;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0030855//epithelial cell differentiation;GO:0000278//mitotic cell cycle;GO:0006298//mismatch repair;GO:0006284//base-excision repair;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006275//regulation of DNA replication",GO:0030971//receptor tyrosine kinase binding;GO:0070182//DNA polymerase binding;GO:0042802//identical protein binding;GO:0030337//DNA polymerase processivity factor activity;GO:0032139//dinucleotide insertion or deletion binding;GO:0000701//purine-specific mismatch base pair DNA N-glycosylase activity;GO:0032405//MutLalpha complex binding;GO:0005515//protein binding,K04802//DNA replication;HTLV-I infection;Nucleotide excision repair;Base excision repair;Mismatch repair;Cell cycle
51110,0,0,0,5,0,0,0,0,0,0,0,0,"LACTB2;lactamase, beta 2",GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K01069//Pyruvate metabolism
51112,0,1,0,0,8,0,18,1,24,0,0,0,TRAPPC12;trafficking protein particle complex 12,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0016192//vesicle-mediated transport,-,-
51114,0,0,0,0,4,30,0,24,48,0,0,0,"ZDHHC9;zinc finger, DHHC-type containing 9",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0002178//palmitoyltransferase complex;GO:0005789//endoplasmic reticulum membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0005737//cytoplasm,GO:0018345//protein palmitoylation;GO:0018230//peptidyl-L-cysteine S-palmitoylation,GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity;GO:0043849//Ras palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
51115,0,53,23,84,47,0,0,0,22,0,23,0,RMDN1;regulator of microtubule dynamics 1,GO:0005739//mitochondrion;GO:0000922//spindle pole;GO:0005874//microtubule,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
51116,0,0,0,0,0,0,12,0,44,0,0,0,MRPS2;mitochondrial ribosomal protein S2,GO:0015935//small ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
51117,0,0,0,0,13,11,0,34,30,0,19,0,COQ4;coenzyme Q4,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0006744//ubiquinone biosynthetic process,-,-
51118,0,0,0,1,0,0,0,0,0,0,2,0,"UTP11L;UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)",GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0032040//small-subunit processome,GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing;GO:0007399//nervous system development;GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
51119,0,43,0,142,300,0,0,0,0,0,3,0,SBDS;Shwachman-Bodian-Diamond syndrome,GO:0000922//spindle pole;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis;GO:0048539//bone marrow development;GO:0043148//mitotic spindle stabilization;GO:0030282//bone mineralization;GO:0030595//leukocyte chemotaxis;GO:0008283//cell proliferation;GO:0042256//mature ribosome assembly;GO:0001833//inner cell mass cell proliferation,GO:0019843//rRNA binding;GO:0043022//ribosome binding;GO:0044822//poly(A) RNA binding;GO:0008017//microtubule binding;GO:0005515//protein binding,K14574//Ribosome biogenesis in eukaryotes
51121,0,8,0,0,0,0,0,0,0,0,0,0,RPL26L1;ribosomal protein L26-like 1,GO:0005829//cytosol;GO:0015934//large ribosomal subunit;GO:0070062//extracellular vesicular exosome,"GO:0016032//viral process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003735//structural constituent of ribosome,K02898//Ribosome
51122,0,1,0,0,39,11,0,55,0,198,0,0,COMMD2;COMM domain containing 2,-,-,GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome
51123,0,4,0,13,35,5,0,1,22,0,0,0,ZNF706;zinc finger protein 706,-,-,GO:0046872//metal ion binding,-
51124,0,25,0,12,2,0,0,0,0,0,0,0,IER3IP1;immediate early response 3 interacting protein 1,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:2000269//regulation of fibroblast apoptotic process,-,-
51125,0,0,0,13,23,0,0,0,13,0,0,130,GOLGA7;golgin A7,GO:0002178//palmitoyltransferase complex;GO:0005795//Golgi stack;GO:0070062//extracellular vesicular exosome;GO:0031228//intrinsic component of Golgi membrane,GO:0050821//protein stabilization;GO:0043001//Golgi to plasma membrane protein transport;GO:0018230//peptidyl-L-cysteine S-palmitoylation,GO:0005515//protein binding,K05546//Protein processing in endoplasmic reticulum;N-Glycan biosynthesis;Metabolic pathways
51126,0,128,0,43,64,0,27,0,2,1,45,0,"NAA20;N(alpha)-acetyltransferase 20, NatB catalytic subunit",GO:0005622//intracellular;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008152//metabolic process,GO:0004596//peptide alpha-N-acetyltransferase activity,-
51127,70,0,0,0,0,14,0,0,37,0,1,0,TRIM17;tripartite motif containing 17,GO:0005622//intracellular,GO:0051865//protein autoubiquitination,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
51128,0,51,2,113,317,1,0,14,75,32,9,73,"SAR1B;secretion associated, Ras related GTPase 1B",GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane,GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0006184//GTP catabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0044281//small molecule metabolic process;GO:0048208//COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0043687//post-translational protein modification;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I,GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07953//Legionellosis;Protein processing in endoplasmic reticulum
51129,0,0,0,8,21,8,0,0,10,0,0,0,ANGPTL4;angiopoietin-like 4,GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005576//extracellular region,GO:0044281//small molecule metabolic process;GO:0070328//triglyceride homeostasis;GO:0001525//angiogenesis;GO:0044255//cellular lipid metabolic process;GO:0051260//protein homooligomerization;GO:0045766//positive regulation of angiogenesis;GO:0030154//cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0001666//response to hypoxia,GO:0005515//protein binding;GO:0004857//enzyme inhibitor activity,K08767//PPAR signaling pathway
51130,0,0,0,0,68,0,0,0,6,129,15,0,ASB3;ankyrin repeat and SOCS box containing 3,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
51131,0,39,0,17,12,0,0,0,0,0,2,0,PHF11;PHD finger protein 11,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding,K11421//Lysine degradation;K09186//Transcriptional misregulation in cancer;Lysine degradation;K14959//Lysine degradation
51132,0,106,0,72,427,0,38,0,54,0,3,320,"RLIM;ring finger protein, LIM domain interacting",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0017053//transcriptional repressor complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006351//transcription, DNA-templated;GO:0060816//random inactivation of X chromosome;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016567//protein ubiquitination",GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,K13126//RNA transport;mRNA surveillance pathway;RNA degradation
51133,91,77,2,132,403,30,0,1,81,0,0,0,KCTD3;potassium channel tetramerization domain containing 3,-,GO:0051260//protein homooligomerization,-,K04892//Serotonergic synapse;K08023//TGF-beta signaling pathway
51134,0,0,0,0,0,0,37,0,0,0,0,0,CEP83;centrosomal protein 83kDa,GO:0005814//centriole;GO:0097539//ciliary transition fiber;GO:0005794//Golgi apparatus,GO:0071539//protein localization to centrosome;GO:0048278//vesicle docking;GO:0042384//cilium assembly,GO:0005515//protein binding,K04514//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Wnt signaling pathway;Pathogenic Escherichia coli infection;Focal adhesion;Axon guidance;Chemokine signaling pathway;Salmonella infection;TGF-beta signaling pathway;Shigellosis;Leukocyte transendothelial migration
51135,96,28,1,2,9,0,0,55,24,0,15,1,IRAK4;interleukin-1 receptor-associated kinase 4,GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005886//plasma membrane,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0034134//toll-like receptor 2 signaling pathway;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006468//protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0001816//cytokine production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005149//interleukin-1 receptor binding,K04733//Chagas disease (American trypanosomiasis);NF-kappa B signaling pathway;Tuberculosis;Pertussis;Influenza A;Toll-like receptor signaling pathway;Apoptosis;Leishmaniasis;Toxoplasmosis;Neurotrophin signaling pathway;Measles
51136,0,0,0,8,0,0,0,0,0,0,0,0,"RNFT1;ring finger protein, transmembrane 1",GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,K11981//Endocytosis
51138,0,0,0,4,13,0,0,0,20,0,1,0,COPS4;COP9 signalosome subunit 4,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0008180//COP9 signalosome;GO:0030054//cell junction;GO:0008021//synaptic vesicle,GO:0010388//cullin deneddylation;GO:0000338//protein deneddylation,GO:0005515//protein binding,-
51141,0,20,0,7,15,9,0,1,0,1,1,2,INSIG2;insulin induced gene 2,GO:0005789//endoplasmic reticulum membrane;GO:0032937//SREBP-SCAP-Insig complex,GO:0006695//cholesterol biosynthetic process;GO:0070542//response to fatty acid;GO:0060363//cranial suture morphogenesis;GO:0060021//palate development;GO:0006641//triglyceride metabolic process;GO:0042472//inner ear morphogenesis;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0042474//middle ear morphogenesis;GO:0010894//negative regulation of steroid biosynthetic process;GO:0032933//SREBP signaling pathway;GO:0032868//response to insulin;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0008134//transcription factor binding,-
51142,0,84,0,69,188,0,22,2,16,0,0,0,CHCHD2;coiled-coil-helix-coiled-coil-helix domain containing 2,GO:0005739//mitochondrion,-,-,-
51143,0,81,0,45,68,10,0,117,82,0,66,1,"DYNC1LI1;dynein, cytoplasmic 1, light intermediate chain 1",GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005868//cytoplasmic dynein complex;GO:0005886//plasma membrane;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane,GO:0007067//mitotic nuclear division;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0008152//metabolic process;GO:0016032//viral process;GO:0006810//transport;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,K10416//Salmonella infection;Vasopressin-regulated water reabsorption;Phagosome
51144,0,1,0,12,8,0,0,117,7,0,7,0,HSD17B12;hydroxysteroid (17-beta) dehydrogenase 12,GO:0005789//endoplasmic reticulum membrane;GO:0031012//extracellular matrix;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0010811//positive regulation of cell-substrate adhesion;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0030198//extracellular matrix organization;GO:0019432//triglyceride biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0044281//small molecule metabolic process,GO:0005518//collagen binding;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0001968//fibronectin binding,K10251//Metabolic pathways;Fatty acid elongation;Biosynthesis of secondary metabolites;Biosynthesis of unsaturated fatty acids;Steroid hormone biosynthesis;K00044//Steroid hormone biosynthesis;Biosynthesis of unsaturated fatty acids;Fatty acid elongation;Metabolic pathways
51146,0,0,0,0,0,0,0,0,0,0,4,0,"A4GNT;alpha-1,4-N-acetylglucosaminyltransferase",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0009101//glycoprotein biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006493//protein O-linked glycosylation;GO:0050680//negative regulation of epithelial cell proliferation,GO:0008375//acetylglucosaminyltransferase activity,-
51147,0,1,1,0,42,0,32,0,9,0,0,0,"ING4;inhibitor of growth family, member 4",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex,"GO:0008285//negative regulation of cell proliferation;GO:0045926//negative regulation of growth;GO:0043065//positive regulation of apoptotic process;GO:0006473//protein acetylation;GO:0006325//chromatin organization;GO:0006260//DNA replication;GO:0043981//histone H4-K5 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0007050//cell cycle arrest;GO:0043984//histone H4-K16 acetylation;GO:0043966//histone H3 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0043982//histone H4-K8 acetylation",GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding,-
51148,5,0,0,0,0,0,17,0,39,0,0,0,CERCAM;cerebral endothelial cell adhesion molecule,GO:0005886//plasma membrane;GO:0005788//endoplasmic reticulum lumen,GO:0007155//cell adhesion;GO:0006928//cellular component movement;GO:0007159//leukocyte cell-cell adhesion;GO:0009103//lipopolysaccharide biosynthetic process,-,K11703//Lysine degradation;Other types of O-glycan biosynthesis
51150,0,0,0,0,5,0,0,0,7,0,0,0,SDF4;stromal cell derived factor 4,GO:0005796//Golgi lumen;GO:0005737//cytoplasm;GO:0032059//bleb;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0005770//late endosome,GO:0045471//response to ethanol;GO:0070625//zymogen granule exocytosis;GO:0045444//fat cell differentiation;GO:0009650//UV protection;GO:0021549//cerebellum development;GO:0017156//calcium ion-dependent exocytosis,GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
51151,0,0,0,0,0,18,0,0,6,0,9,0,"SLC45A2;solute carrier family 45, member 2",GO:0016021//integral component of membrane;GO:0033162//melanosome membrane,GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0042438//melanin biosynthetic process;GO:0048066//developmental pigmentation,-,-
51154,0,2,0,1,10,0,0,0,82,0,0,0,MRTO4;mRNA turnover 4 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0031965//nuclear membrane;GO:0005634//nucleus,GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding,-
51155,0,0,0,5,61,19,2,0,0,0,2,0,HN1;hematological and neurological expressed 1,GO:0005634//nucleus,GO:0032502//developmental process,-,-
51156,194,0,0,0,0,0,0,0,43,0,0,0,"SERPINA10;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0030162//regulation of proteolysis;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:0060046//regulation of acrosome reaction,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0008201//heparin binding,K03984//Complement and coagulation cascades
51157,0,0,0,8,1,0,0,0,25,0,0,0,ZNF580;zinc finger protein 580,GO:0005634//nucleus,"GO:0002690//positive regulation of leukocyte chemotaxis;GO:0006355//regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0001938//positive regulation of endothelial cell proliferation;GO:0032757//positive regulation of interleukin-8 production;GO:0010628//positive regulation of gene expression;GO:0006935//chemotaxis;GO:0070301//cellular response to hydrogen peroxide;GO:0006351//transcription, DNA-templated;GO:0010595//positive regulation of endothelial cell migration",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
5116,0,0,0,11,51,47,40,115,55,155,13,0,PCNT;pericentrin,GO:0005874//microtubule;GO:0005829//cytosol;GO:0005814//centriole;GO:0000242//pericentriolar material;GO:0031514//motile cilium;GO:0045171//intercellular bridge;GO:0034451//centriolar satellite;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0036064//ciliary basal body,GO:0007051//spindle organization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0042384//cilium assembly;GO:0000226//microtubule cytoskeleton organization;GO:0035108//limb morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0061351//neural precursor cell proliferation;GO:0021696//cerebellar cortex morphogenesis;GO:0035264//multicellular organism growth;GO:0001764//neuron migration;GO:0090316//positive regulation of intracellular protein transport;GO:0021772//olfactory bulb development;GO:0048854//brain morphogenesis;GO:0001701//in utero embryonic development,GO:0005516//calmodulin binding;GO:0005515//protein binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
51160,0,0,0,3,18,0,0,0,35,0,31,0,VPS28;vacuolar protein sorting 28 homolog (S. cerevisiae),GO:0005768//endosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex,GO:0019082//viral protein processing;GO:0075733//intracellular transport of virus;GO:0061024//membrane organization;GO:0016197//endosomal transport;GO:0031397//negative regulation of protein ubiquitination;GO:0019068//virion assembly;GO:0015031//protein transport;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0016032//viral process;GO:0019058//viral life cycle,GO:0005515//protein binding,K12184//Endocytosis
51161,52,42,0,12,34,0,0,0,15,0,110,0,C3orf18;chromosome 3 open reading frame 18,GO:0016021//integral component of membrane,-,-,-
51162,0,0,0,0,0,11,24,43,17,0,12,0,"EGFL7;EGF-like-domain, multiple 7",GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031012//extracellular matrix,GO:0045746//negative regulation of Notch signaling pathway;GO:0001568//blood vessel development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0030336//negative regulation of cell migration;GO:0007155//cell adhesion;GO:0001570//vasculogenesis;GO:0001525//angiogenesis,GO:0005509//calcium ion binding;GO:0005112//Notch binding,K06824//ECM-receptor interaction
51163,0,0,0,17,3,0,0,0,2,0,0,0,DBR1;debranching RNA lariats 1,GO:0005634//nucleus,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0008419//RNA lariat debranching enzyme activity,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption
51164,5,72,0,61,92,34,0,0,60,0,0,0,DCTN4;dynactin 4 (p62),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005869//dynactin complex;GO:0005829//cytosol,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0047485//protein N-terminus binding,K10426//Huntington's disease;Vasopressin-regulated water reabsorption
51166,69,0,0,2,38,6,0,101,0,0,0,1,AADAT;aminoadipate aminotransferase,GO:0005759//mitochondrial matrix,GO:0097052//L-kynurenine metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0006569//tryptophan catabolic process;GO:0006554//lysine catabolic process;GO:0044281//small molecule metabolic process;GO:0006536//glutamate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0033512//L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0019441//tryptophan catabolic process to kynurenine;GO:0009058//biosynthetic process,GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0042803//protein homodimerization activity;GO:0030170//pyridoxal phosphate binding;GO:0047536//2-aminoadipate transaminase activity,K00825//Metabolic pathways;Lysine biosynthesis;Tryptophan metabolism;Lysine degradation
51167,0,18,2,0,0,1,39,0,26,0,0,0,CYB5R4;cytochrome b5 reductase 4,GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum,GO:0006091//generation of precursor metabolites and energy;GO:0055114//oxidation-reduction process;GO:0006801//superoxide metabolic process;GO:0042593//glucose homeostasis;GO:0030073//insulin secretion;GO:0003032//detection of oxygen;GO:0048468//cell development;GO:0046677//response to antibiotic;GO:0006739//NADP metabolic process,"GO:0050660//flavin adenine dinucleotide binding;GO:0020037//heme binding;GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0046872//metal ion binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0016174//NAD(P)H oxidase activity",K00326//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
51168,6,0,62,10,0,17,102,251,138,0,31,0,MYO15A;myosin XVA,GO:0070062//extracellular vesicular exosome;GO:0016459//myosin complex;GO:0032420//stereocilium;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis,GO:0003774//motor activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding,-
51170,13,0,0,0,8,0,24,0,0,0,0,0,HSD17B11;hydroxysteroid (17-beta) dehydrogenase 11,GO:0005737//cytoplasm;GO:0005811//lipid particle;GO:0005576//extracellular region,GO:0006694//steroid biosynthetic process;GO:0006710//androgen catabolic process;GO:0055114//oxidation-reduction process,GO:0004303//estradiol 17-beta-dehydrogenase activity,K15734//Retinol metabolism
51171,0,0,1,0,18,0,0,0,37,0,0,0,HSD17B14;hydroxysteroid (17-beta) dehydrogenase 14,GO:0005829//cytosol,GO:0006706//steroid catabolic process;GO:0055114//oxidation-reduction process,GO:0005515//protein binding;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0004303//estradiol 17-beta-dehydrogenase activity,K00019//Butanoate metabolism;Metabolic pathways;Synthesis and degradation of ketone bodies;K13370//Steroid hormone biosynthesis;Metabolic pathways
51172,0,33,0,0,0,21,0,77,8,0,6,0,NAGPA;N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase,GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane,GO:0006622//protein targeting to lysosome;GO:0007040//lysosome organization;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation,GO:0003944//N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity,K01125//Lysosome
51174,54,0,0,0,0,0,0,0,9,0,8,34,"TUBD1;tubulin, delta 1",GO:0005874//microtubule;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005730//nucleolus,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0007017//microtubule-based process;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0030154//cell differentiation,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005200//structural constituent of cytoskeleton,-
51175,0,0,0,0,0,4,21,0,9,0,0,280,"TUBE1;tubulin, epsilon 1",GO:0000242//pericentriolar material;GO:0005874//microtubule,GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0007098//centrosome cycle,GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
51176,0,0,0,0,0,6,0,0,47,0,0,0,LEF1;lymphoid enhancer-binding factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0032993//protein-DNA complex,"GO:0030509//BMP signaling pathway;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0021854//hypothalamus development;GO:0060326//cell chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0048069//eye pigmentation;GO:0045063//T-helper 1 cell differentiation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0002040//sprouting angiogenesis;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001755//neural crest cell migration;GO:0021943//formation of radial glial scaffolds;GO:0043401//steroid hormone mediated signaling pathway;GO:0001569//patterning of blood vessels;GO:0022408//negative regulation of cell-cell adhesion;GO:0043967//histone H4 acetylation;GO:0071353//cellular response to interleukin-4;GO:0071866//negative regulation of apoptotic process in bone marrow;GO:0071895//odontoblast differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0060710//chorio-allantoic fusion;GO:0043586//tongue development;GO:0033153//T cell receptor V(D)J recombination;GO:0001756//somitogenesis;GO:0060561//apoptotic process involved in morphogenesis;GO:0060033//anatomical structure regression;GO:0030854//positive regulation of granulocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030879//mammary gland development;GO:0032714//negative regulation of interleukin-5 production;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043966//histone H3 acetylation;GO:0090068//positive regulation of cell cycle process;GO:0071345//cellular response to cytokine stimulus;GO:0021879//forebrain neuron differentiation;GO:0060021//palate development;GO:0030307//positive regulation of cell growth;GO:0030223//neutrophil differentiation;GO:1902262//apoptotic process involved in patterning of blood vessels;GO:0032696//negative regulation of interleukin-13 production;GO:0030326//embryonic limb morphogenesis;GO:0046632//alpha-beta T cell differentiation;GO:0022409//positive regulation of cell-cell adhesion;GO:0043923//positive regulation by host of viral transcription;GO:0016202//regulation of striated muscle tissue development;GO:0050909//sensory perception of taste;GO:0071899//negative regulation of estrogen receptor binding;GO:0021873//forebrain neuroblast division;GO:0016055//Wnt signaling pathway;GO:0021861//forebrain radial glial cell differentiation;GO:0032713//negative regulation of interleukin-4 production;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001649//osteoblast differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060325//face morphogenesis;GO:0048341//paraxial mesoderm formation;GO:0045843//negative regulation of striated muscle tissue development;GO:0030335//positive regulation of cell migration;GO:0001837//epithelial to mesenchymal transition;GO:0048747//muscle fiber development;GO:0042100//B cell proliferation;GO:0061153//trachea gland development;GO:0006366//transcription from RNA polymerase II promoter;GO:0071864//positive regulation of cell proliferation in bone marrow;GO:0022407//regulation of cell-cell adhesion;GO:0021542//dentate gyrus development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding","GO:0003682//chromatin binding;GO:0045295//gamma-catenin binding;GO:0008301//DNA binding, bending;GO:0035326//enhancer binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0030331//estrogen receptor binding;GO:0003677//DNA binding;GO:0030284//estrogen receptor activity;GO:0008134//transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0070016//armadillo repeat domain binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0070742//C2H2 zinc finger domain binding;GO:0008013//beta-catenin binding;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity",K04492//Colorectal cancer;Melanogenesis;Thyroid cancer;Adherens junction;Wnt signaling pathway;Endometrial cancer;Basal cell carcinoma;Prostate cancer;Acute myeloid leukemia;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer
51177,0,0,0,0,0,0,41,0,0,0,0,204,"PLEKHO1;pleckstrin homology domain containing, family O member 1",GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
51179,85,0,0,0,0,0,36,0,15,0,0,0,HAO2;hydroxyacid oxidase 2 (long chain),GO:0005777//peroxisome;GO:0070062//extracellular vesicular exosome,GO:0019395//fatty acid oxidation,GO:0052853//long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity;GO:0010181//FMN binding;GO:0005102//receptor binding;GO:0052852//very-long-chain-(S)-2-hydroxy-acid oxidase activity;GO:0052854//medium-chain-(S)-2-hydroxy-acid oxidase activity,K11517//Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Biosynthesis of secondary metabolites;Peroxisome
5118,0,0,0,0,0,10,0,0,11,0,0,0,PCOLCE;procollagen C-endopeptidase enhancer,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0031012//extracellular matrix,GO:0007275//multicellular organismal development;GO:0010952//positive regulation of peptidase activity;GO:0006508//proteolysis,GO:0005518//collagen binding;GO:0016504//peptidase activator activity;GO:0008201//heparin binding;GO:0005515//protein binding,-
51181,0,2,1,32,31,0,48,0,1,21,1,0,DCXR;dicarbonyl/L-xylulose reductase,GO:0005903//brush border;GO:0005634//nucleus;GO:0005902//microvillus;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005881//cytoplasmic microtubule,GO:0055114//oxidation-reduction process;GO:0051289//protein homotetramerization;GO:0005997//xylulose metabolic process;GO:0042732//D-xylose metabolic process;GO:0006006//glucose metabolic process;GO:0006739//NADP metabolic process,"GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0050038//L-xylulose reductase (NADP+) activity",K03331//Pentose and glucuronate interconversions;Metabolic pathways
51182,0,1,0,0,54,45,116,0,22,0,30,0,HSPA14;heat shock 70kDa protein 14,GO:0016020//membrane;GO:0005829//cytosol;GO:0005840//ribosome,GO:0051083//'de novo' cotranslational protein folding,GO:0005515//protein binding;GO:0005524//ATP binding,K03283//Epstein-Barr virus infection;Antigen processing and presentation;Measles;Toxoplasmosis;Protein processing in endoplasmic reticulum;Prion diseases;MAPK signaling pathway;Influenza A;Legionellosis;Endocytosis;Spliceosome;K11447//Transcriptional misregulation in cancer
51184,0,0,0,0,0,0,0,54,13,156,0,0,GPN3;GPN-loop GTPase 3,GO:0043234//protein complex,-,GO:0005525//GTP binding,-
51185,0,121,1,126,183,0,14,0,21,0,9,0,CRBN;cereblon,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0005730//nucleolus,GO:0090073//positive regulation of protein homodimerization activity;GO:0016567//protein ubiquitination;GO:0032463//negative regulation of protein homooligomerization;GO:0006200//ATP catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0034766//negative regulation of ion transmembrane transport,GO:0004176//ATP-dependent peptidase activity;GO:0005515//protein binding,-
51186,0,1,0,5,19,0,0,0,0,0,0,0,WBP5;WW domain binding protein 5,-,-,GO:0050699//WW domain binding,K12465//Neurotrophin signaling pathway
51187,0,26,0,10,50,0,0,0,0,0,0,0,RSL24D1;ribosomal L24 domain containing 1,GO:0005730//nucleolus,GO:0042254//ribosome biogenesis,-,K02896//Ribosome
51188,0,0,0,6,27,0,0,53,0,0,0,0,SS18L2;synovial sarcoma translocation gene on chromosome 18-like 2,-,-,-,K15623//Transcriptional misregulation in cancer
5119,0,0,1,1,16,0,0,0,12,0,14,0,CHMP1A;charged multivesicular body protein 1A,GO:0016363//nuclear matrix;GO:0005815//microtubule organizing center;GO:0010008//endosome membrane;GO:0000794//condensed nuclear chromosome;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0012505//endomembrane system,"GO:0016458//gene silencing;GO:0016192//vesicle-mediated transport;GO:0045014//negative regulation of transcription by glucose;GO:0007076//mitotic chromosome condensation;GO:0000910//cytokinesis;GO:0015031//protein transport;GO:0006508//proteolysis;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0019904//protein domain specific binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,K12197//Endocytosis
51191,0,0,0,1,11,0,63,0,50,0,0,0,HERC5;HECT and RLD domain containing E3 ubiquitin protein ligase 5,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032480//negative regulation of type I interferon production;GO:0050688//regulation of defense response to virus;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0032020//ISG15-protein conjugation;GO:0019221//cytokine-mediated signaling pathway,GO:0042296//ISG15 ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K10615//Ubiquitin mediated proteolysis
51192,0,0,0,5,11,0,0,0,0,0,24,0,CKLF;chemokine-like factor,GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005615//extracellular space,GO:0008283//cell proliferation;GO:0048247//lymphocyte chemotaxis;GO:0032940//secretion by cell;GO:0030593//neutrophil chemotaxis;GO:0048246//macrophage chemotaxis,GO:0008009//chemokine activity,-
51193,0,0,0,0,14,9,31,0,26,1,18,0,ZNF639;zinc finger protein 639,GO:0005634//nucleus,"GO:0043923//positive regulation by host of viral transcription;GO:0043922//negative regulation by host of viral transcription;GO:0030307//positive regulation of cell growth;GO:0006351//transcription, DNA-templated;GO:0046718//viral entry into host cell;GO:0045892//negative regulation of transcription, DNA-templated",GO:0043621//protein self-association;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding,-
51194,54,0,0,0,14,26,22,0,59,0,11,0,IPO11;importin 11,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006610//ribosomal protein import into nucleus,GO:0008565//protein transporter activity;GO:0008536//Ran GTPase binding,-
51195,3,0,0,0,0,46,0,0,24,0,0,127,RAPGEFL1;Rap guanine nucleotide exchange factor (GEF)-like 1,GO:0016020//membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007399//nervous system development;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity,K04351//Leukocyte transendothelial migration
51196,1,3,1,7,9,32,24,80,145,0,0,502,"PLCE1;phospholipase C, epsilon 1",GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007265//Ras protein signal transduction;GO:0006651//diacylglycerol biosynthetic process;GO:0007507//heart development;GO:0044281//small molecule metabolic process;GO:0043547//positive regulation of GTPase activity;GO:0006940//regulation of smooth muscle contraction;GO:0046578//regulation of Ras protein signal transduction;GO:0001558//regulation of cell growth;GO:0032835//glomerulus development;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0016042//lipid catabolic process;GO:0007010//cytoskeleton organization;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0008283//cell proliferation;GO:0000187//activation of MAPK activity;GO:0048016//inositol phosphate-mediated signaling;GO:0045859//regulation of protein kinase activity;GO:0019722//calcium-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006644//phospholipid metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0005057//receptor signaling protein activity;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0017016//Ras GTPase binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0004629//phospholipase C activity,K05860//Inositol phosphate metabolism;Calcium signaling pathway;Metabolic pathways;Phosphatidylinositol signaling system
51199,65,199,21,33,227,14,24,0,29,0,13,297,NIN;ninein (GSK3B interacting protein),GO:0005813//centrosome;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005730//nucleolus;GO:0005814//centriole,GO:0090222//centrosome-templated microtubule nucleation;GO:0034454//microtubule anchoring at centrosome;GO:0051642//centrosome localization,GO:0005525//GTP binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K00688//Insulin signaling pathway;Starch and sucrose metabolism
51200,0,0,0,0,0,32,0,0,24,31,2,1,CPA4;carboxypeptidase A4,GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0016573//histone acetylation,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,-
51201,0,0,0,28,95,0,19,107,12,0,0,0,"ZDHHC2;zinc finger, DHHC-type containing 2",GO:0005887//integral component of plasma membrane;GO:0055038//recycling endosome membrane;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0018345//protein palmitoylation,GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
51202,0,0,0,1,38,0,0,0,0,0,0,0,DDX47;DEAD (Asp-Glu-Ala-Asp) box polypeptide 47,GO:0005730//nucleolus;GO:0016020//membrane,GO:0008380//RNA splicing;GO:0006200//ATP catabolic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0006397//mRNA processing;GO:0006364//rRNA processing,GO:0008026//ATP-dependent helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
51204,0,0,0,0,7,0,40,0,8,0,0,0,TACO1;translational activator of mitochondrially encoded cytochrome c oxidase I,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0006417//regulation of translation,-,-
51205,0,28,1,0,2,0,0,0,2,0,6,0,"ACP6;acid phosphatase 6, lysophosphatidic",GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0016311//dephosphorylation;GO:2001311//lysobisphosphatidic acid metabolic process;GO:0006644//phospholipid metabolic process,GO:0003993//acid phosphatase activity;GO:0052642//lysophosphatidic acid phosphatase activity,K14395//Riboflavin metabolism
51206,118,0,0,0,0,6,10,71,0,0,0,0,GP6;glycoprotein VI (platelet),GO:0005887//integral component of plasma membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0050900//leukocyte migration;GO:0030168//platelet activation;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0007596//blood coagulation,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0005518//collagen binding,K06264//ECM-receptor interaction
51207,0,0,0,0,0,11,0,0,31,0,0,0,DUSP13;dual specificity phosphatase 13,GO:0005737//cytoplasm,GO:0007126//meiotic nuclear division;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0007283//spermatogenesis,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,-
51208,0,0,0,0,10,0,0,0,41,0,4,0,CLDN18;claudin 18,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//tight junction assembly;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
51209,0,0,0,2,0,17,15,0,0,0,0,0,"RAB9B;RAB9B, member RAS oncogene family",GO:0045335//phagocytic vesicle;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005515//protein binding;GO:0019003//GDP binding;GO:0005525//GTP binding,K07900//Measles
51213,0,0,0,0,0,0,0,0,8,0,0,0,LUZP4;leucine zipper protein 4,GO:0005634//nucleus,-,-,-
51214,0,0,0,0,0,8,0,0,0,0,0,0,IGF2-AS;IGF2 antisense RNA,-,-,-,-
51218,0,9,0,5,51,0,0,0,23,0,0,0,GLRX5;glutaredoxin 5,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process;GO:0030097//hemopoiesis;GO:0045454//cell redox homeostasis,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0046872//metal ion binding;GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity",-
5122,0,0,0,0,0,0,0,0,18,0,0,0,PCSK1;proprotein convertase subtilisin/kexin type 1,GO:0005794//Golgi apparatus;GO:0005615//extracellular space;GO:0030133//transport vesicle;GO:0034774//secretory granule lumen,GO:0007267//cell-cell signaling;GO:0050796//regulation of insulin secretion;GO:0016486//peptide hormone processing;GO:0006508//proteolysis;GO:0008152//metabolic process;GO:0044267//cellular protein metabolic process;GO:0043043//peptide biosynthetic process,GO:0004252//serine-type endopeptidase activity,-
51222,0,0,0,3,0,0,0,23,0,0,8,2,ZNF219;zinc finger protein 219,GO:0005634//nucleus;GO:0016021//integral component of membrane,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001505//regulation of neurotransmitter levels;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004969//histamine receptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
51224,16,0,0,0,0,0,17,0,1,0,0,0,TCEB3B;transcription elongation factor B polypeptide 3B (elongin A2),GO:0016021//integral component of membrane;GO:0005634//nucleus,"GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding,-
51225,0,0,0,0,0,0,0,0,7,0,0,0,"ABI3;ABI family, member 3",GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005622//intracellular;GO:0016020//membrane,GO:0030334//regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006928//cellular component movement,GO:0005515//protein binding,K05751//Regulation of actin cytoskeleton
51226,0,0,0,0,0,0,0,0,11,0,7,0,"COPZ2;coatomer protein complex, subunit zeta 2",GO:0030126//COPI vesicle coat;GO:0005801//cis-Golgi network;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,-,K12399//Lysosome;K12403//Lysosome;K02604//Cell cycle;Cell cycle - yeast;Meiosis - yeast
51227,0,0,0,3,1,16,0,0,3,0,9,0,"PIGP;phosphatidylinositol glycan anchor biosynthesis, class P",GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0016254//preassembly of GPI anchor in ER membrane;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation,GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity,K03861//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
51228,0,0,0,22,45,16,0,60,10,0,0,0,GLTP;glycolipid transfer protein,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0046836//glycolipid transport,GO:0051861//glycolipid binding;GO:0008289//lipid binding;GO:0017089//glycolipid transporter activity,K11447//Transcriptional misregulation in cancer
51230,0,0,0,14,29,0,16,0,69,0,7,0,PHF20;PHD finger protein 20,GO:0005730//nucleolus;GO:0000123//histone acetyltransferase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0071339//MLL1 complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0043984//histone H4-K16 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0006351//transcription, DNA-templated;GO:0043982//histone H4-K8 acetylation",GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
51231,0,2,1,13,4,0,8,59,31,0,0,0,VRK3;vaccinia related kinase 3,GO:0005634//nucleus,GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0019903//protein phosphatase binding;GO:0005524//ATP binding,-
51232,0,0,0,0,0,13,67,0,31,0,0,184,CRIM1;cysteine rich transmembrane BMP regulator 1 (chordin-like),GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0007399//nervous system development;GO:0001558//regulation of cell growth;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0030165//PDZ domain binding;GO:0005010//insulin-like growth factor-activated receptor activity;GO:0005520//insulin-like growth factor binding,K04657//TGF-beta signaling pathway
51233,0,0,0,0,0,0,0,0,19,0,0,29,DRICH1;aspartate-rich 1,-,-,-,-
51234,0,0,0,13,0,0,0,1,12,51,0,0,EMC4;ER membrane protein complex subunit 4,GO:0016021//integral component of membrane;GO:0072546//ER membrane protein complex,GO:0006915//apoptotic process,-,-
51237,10,0,0,11,15,0,26,0,0,1,18,0,MZB1;marginal zone B and B1 cell-specific protein,GO:0005788//endoplasmic reticulum lumen;GO:0005737//cytoplasm;GO:0034663//endoplasmic reticulum chaperone complex;GO:0005576//extracellular region,GO:0030888//regulation of B cell proliferation;GO:0006915//apoptotic process;GO:0042127//regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0033622//integrin activation;GO:0002642//positive regulation of immunoglobulin biosynthetic process;GO:2001274//negative regulation of glucose import in response to insulin stimulus,GO:0005515//protein binding,K14611//Vitamin digestion and absorption
51239,0,0,0,0,0,0,0,1,12,0,1,233,ANKRD39;ankyrin repeat domain 39,-,-,-,-
51241,0,26,0,23,82,0,0,0,12,0,4,0,COX16;COX16 cytochrome c oxidase assembly homolog (S. cerevisiae),GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K11447//Transcriptional misregulation in cancer
51244,0,19,0,9,15,8,0,0,24,0,0,0,CCDC174;coiled-coil domain containing 174,GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
51246,0,0,0,0,32,15,2,0,43,0,0,0,SHISA5;shisa family member 5,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,GO:0050699//WW domain binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,K10135//p53 signaling pathway
51247,0,1,3,66,445,7,0,0,0,0,0,0,PAIP2;poly(A) binding protein interacting protein 2,GO:0005737//cytoplasm,GO:0045947//negative regulation of translational initiation;GO:0007613//memory;GO:1900271//regulation of long-term synaptic potentiation;GO:0007283//spermatogenesis,GO:0030371//translation repressor activity;GO:0005515//protein binding;GO:0003729//mRNA binding,-
51248,75,0,2,8,32,18,0,0,28,0,0,0,PDZD11;PDZ domain containing 11,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0005576//extracellular region,-,GO:0008022//protein C-terminus binding;GO:0005515//protein binding,K08018//MAPK signaling pathway
51249,0,11,17,59,69,0,0,0,0,0,34,0,TMEM69;transmembrane protein 69,GO:0016021//integral component of membrane,-,-,K11251//Alcoholism;Systemic lupus erythematosus;K04012//Hematopoietic cell lineage;Epstein-Barr virus infection;Complement and coagulation cascades;B cell receptor signaling pathway
5125,157,0,30,0,13,54,7,0,90,0,24,0,PCSK5;proprotein convertase subtilisin/kexin type 5,GO:0005796//Golgi lumen;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0030141//secretory granule;GO:0005615//extracellular space,GO:0048706//embryonic skeletal system development;GO:0009952//anterior/posterior pattern specification;GO:0016485//protein processing;GO:0030323//respiratory tube development;GO:0042089//cytokine biosynthetic process;GO:0006465//signal peptide processing;GO:0006508//proteolysis;GO:0035108//limb morphogenesis;GO:0048566//embryonic digestive tract development;GO:0043043//peptide biosynthetic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0016486//peptide hormone processing;GO:0001822//kidney development;GO:0032455//nerve growth factor processing;GO:0007507//heart development;GO:0019058//viral life cycle;GO:0007566//embryo implantation;GO:0002001//renin secretion into blood stream,GO:0042277//peptide binding;GO:0008233//peptidase activity;GO:0004252//serine-type endopeptidase activity,-
51250,0,19,0,0,19,12,0,0,24,127,0,0,C6orf203;chromosome 6 open reading frame 203,GO:0005739//mitochondrion,-,-,K12662//Spliceosome
51251,0,0,0,15,15,0,0,0,12,0,0,227,"NT5C3A;5'-nucleotidase, cytosolic IIIA",GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006206//pyrimidine nucleobase metabolic process;GO:0006213//pyrimidine nucleoside metabolic process;GO:0016311//dephosphorylation;GO:0046135//pyrimidine nucleoside catabolic process;GO:0044281//small molecule metabolic process;GO:0009117//nucleotide metabolic process,GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity;GO:0008665//2'-phosphotransferase activity;GO:0000166//nucleotide binding,K01081//Nicotinate and nicotinamide metabolism;Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
51252,0,0,0,0,0,65,32,0,33,0,11,0,"FAM178B;family with sequence similarity 178, member B",-,-,-,K06521//Axon guidance
51253,0,0,0,0,7,0,0,0,19,2,0,0,MRPL37;mitochondrial ribosomal protein L37,GO:0005761//mitochondrial ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
51255,0,0,1,0,1,0,0,0,3,0,0,0,RNF181;ring finger protein 181,-,GO:0051865//protein autoubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
51256,0,0,0,0,1,0,0,0,11,0,0,0,"TBC1D7;TBC1 domain family, member 7",GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0036064//ciliary basal body;GO:0031410//cytoplasmic vesicle,GO:0032862//activation of Rho GTPase activity;GO:0032007//negative regulation of TOR signaling;GO:0070848//response to growth factor;GO:0032851//positive regulation of Rab GTPase activity;GO:0031398//positive regulation of protein ubiquitination;GO:0033126//positive regulation of GTP catabolic process,GO:0017137//Rab GTPase binding;GO:0005097//Rab GTPase activator activity;GO:0005515//protein binding,-
51257,0,1,27,0,5,0,0,0,13,0,16,0,"MARCH2;membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0005765//lysosomal membrane,GO:0006897//endocytosis;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
51258,0,2,2,64,94,0,0,0,0,0,0,0,MRPL51;mitochondrial ribosomal protein L51,GO:0005762//mitochondrial large ribosomal subunit;GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0005515//protein binding,-
51259,0,0,0,0,0,0,0,0,13,0,0,0,TMEM216;transmembrane protein 216,GO:0016021//integral component of membrane;GO:0005929//cilium;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0036038//TCTN-B9D complex,GO:0042384//cilium assembly;GO:0060271//cilium morphogenesis,-,-
5126,0,0,0,0,6,55,0,36,36,0,4,0,PCSK2;proprotein convertase subtilisin/kexin type 2,GO:0043204//perikaryon;GO:0030425//dendrite;GO:0016020//membrane;GO:0005615//extracellular space;GO:0034774//secretory granule lumen;GO:0030133//transport vesicle,GO:0030070//insulin processing;GO:0009790//embryo development;GO:0034231//islet amyloid polypeptide processing;GO:0034230//enkephalin processing;GO:0044267//cellular protein metabolic process;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0007399//nervous system development,GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0032403//protein complex binding,-
51260,0,0,0,21,66,12,0,0,0,0,0,0,PBDC1;polysaccharide biosynthesis domain containing 1,-,-,-,-
51263,0,0,0,54,93,34,62,0,35,0,0,0,MRPL30;mitochondrial ribosomal protein L30,GO:0005840//ribosome;GO:0005739//mitochondrion,-,-,K11447//Transcriptional misregulation in cancer;K14209//Protein digestion and absorption;K03956//Metabolic pathways;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease
51264,0,13,0,3,23,0,0,0,1,0,0,0,MRPL27;mitochondrial ribosomal protein L27,GO:0005762//mitochondrial large ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
51265,0,0,0,0,0,0,0,0,8,0,0,0,CDKL3;cyclin-dependent kinase-like 3,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0006464//cellular protein modification process,GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity,-
51266,0,0,0,0,0,0,3,0,33,0,0,0,"CLEC1B;C-type lectin domain family 1, member B",GO:0005887//integral component of plasma membrane,GO:0030220//platelet formation;GO:0007166//cell surface receptor signaling pathway;GO:0006952//defense response,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding,-
51268,117,0,0,0,0,0,18,0,3,48,0,0,PIPOX;pipecolic acid oxidase,GO:0005777//peroxisome,GO:0046653//tetrahydrofolate metabolic process;GO:0033514//L-lysine catabolic process to acetyl-CoA via L-pipecolate;GO:0055114//oxidation-reduction process,GO:0005102//receptor binding;GO:0050031//L-pipecolate oxidase activity;GO:0008115//sarcosine oxidase activity,"K00306//Metabolic pathways;Glycine, serine and threonine metabolism;Lysine degradation;Peroxisome"
5127,0,0,0,10,24,0,0,0,15,0,12,0,CDK16;cyclin-dependent kinase 16,GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0030133//transport vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0015630//microtubule cytoskeleton,GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0006887//exocytosis;GO:0030252//growth hormone secretion;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0007283//spermatogenesis;GO:0031175//neuron projection development,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
51270,0,0,0,0,0,0,0,2,28,0,0,0,"TFDP3;transcription factor Dp family, member 3",GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0006351//transcription, DNA-templated;GO:0000082//G1/S transition of mitotic cell cycle",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K04683//TGF-beta signaling pathway;Cell cycle
51271,0,0,0,1,27,14,0,48,10,0,14,0,UBAP1;ubiquitin associated protein 1,GO:0005829//cytosol;GO:0000813//ESCRT I complex;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway,GO:0043130//ubiquitin binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
51272,0,21,2,1,21,0,0,0,15,0,0,0,BET1L;Bet1 golgi vesicular membrane trafficking protein-like,GO:0031201//SNARE complex;GO:0005795//Golgi stack;GO:0030173//integral component of Golgi membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0016020//membrane,"GO:0042147//retrograde transport, endosome to Golgi;GO:0015031//protein transport",GO:0005484//SNAP receptor activity,K08504//SNARE interactions in vesicular transport
51274,66,61,0,85,75,13,89,0,13,189,2,0,KLF3;Kruppel-like factor 3 (basic),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:1901653//cellular response to peptide;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K15605//Transcriptional misregulation in cancer
51275,0,267,22,135,223,0,16,220,97,1,260,0,MAPKAPK5-AS1;MAPKAPK5 antisense RNA 1,-,-,-,K04442//MAPK signaling pathway
51276,0,35,159,25,55,3,0,101,0,0,49,0,ZNF571;zinc finger protein 571,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
51277,0,0,1,8,0,0,0,0,27,0,19,0,"DNAJC27;DnaJ (Hsp40) homolog, subfamily C, member 27",GO:0005739//mitochondrion,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
51278,0,0,0,0,5,0,0,3,25,0,17,0,IER5;immediate early response 5,-,-,-,-
5128,0,30,0,13,67,48,0,34,18,0,1,0,CDK17;cyclin-dependent kinase 17,-,GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle,GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,-
51280,326,24,61,85,88,0,0,16,13,7,48,634,GOLM1;golgi membrane protein 1,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,GO:0006997//nucleus organization;GO:0019216//regulation of lipid metabolic process,GO:0005515//protein binding,-
51281,10,0,0,0,14,14,27,61,9,0,14,0,ANKMY1;ankyrin repeat and MYND domain containing 1,-,-,GO:0046872//metal ion binding,-
51282,43,67,0,58,60,0,0,0,49,0,123,0,SCAND1;SCAN domain containing 1,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0042802//identical protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
51283,0,0,0,9,0,0,0,0,37,0,11,0,BFAR;bifunctional apoptosis regulator,GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process,GO:0008270//zinc ion binding;GO:0005198//structural molecule activity,-
51284,0,0,0,0,0,1,0,0,0,0,6,0,TLR7;toll-like receptor 7,GO:0032009//early phagosome;GO:0005737//cytoplasm;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005764//lysosome;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex;GO:0036020//endolysosome membrane,GO:0045416//positive regulation of interleukin-8 biosynthetic process;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0002282//microglial cell activation involved in immune response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006954//inflammatory response;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0051607//defense response to virus;GO:0032755//positive regulation of interleukin-6 production;GO:0034154//toll-like receptor 7 signaling pathway;GO:0007252//I-kappaB phosphorylation;GO:0045356//positive regulation of interferon-alpha biosynthetic process;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0071260//cellular response to mechanical stimulus;GO:0032757//positive regulation of interleukin-8 production;GO:0034162//toll-like receptor 9 signaling pathway,GO:0003727//single-stranded RNA binding;GO:0035197//siRNA binding;GO:0003725//double-stranded RNA binding;GO:0004888//transmembrane signaling receptor activity;GO:0008144//drug binding,K05404//Measles;Influenza A;Toll-like receptor signaling pathway
51285,0,0,0,0,0,14,0,0,26,0,0,0,"RASL12;RAS-like, family 12",GO:0016020//membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005525//GTP binding,-
51286,0,0,0,0,0,24,0,0,16,0,0,0,CEND1;cell cycle exit and neuronal differentiation 1,GO:0016021//integral component of membrane,GO:0021702//cerebellar Purkinje cell differentiation;GO:0021941//negative regulation of cerebellar granule cell precursor proliferation;GO:0007628//adult walking behavior;GO:0021933//radial glia guided migration of cerebellar granule cell,-,-
51287,0,1,1,26,91,0,0,0,3,0,2,0,COA4;cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae),GO:0005739//mitochondrion,-,-,-
51289,0,0,0,0,0,0,0,0,13,176,12,0,RXFP3;relaxin/insulin-like family peptide receptor 3,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway,GO:0008528//G-protein coupled peptide receptor activity;GO:0004930//G-protein coupled receptor activity,-
5129,27,0,0,0,0,41,0,0,33,0,0,0,CDK18;cyclin-dependent kinase 18,-,GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle,GO:0005515//protein binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
51290,0,0,0,11,25,21,21,0,31,0,0,0,ERGIC2;ERGIC and golgi 2,GO:0005789//endoplasmic reticulum membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0016192//vesicle-mediated transport,-,-
51291,0,0,0,0,0,12,1,0,18,0,2,0,GMIP;GEM interacting protein,GO:0005622//intracellular;GO:0005829//cytosol,GO:0034259//negative regulation of Rho GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0035556//intracellular signal transduction,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005100//Rho GTPase activator activity,K02649//Aldosterone-regulated sodium reabsorption;Prostate cancer;Small cell lung cancer;Progesterone-mediated oocyte maturation;Carbohydrate digestion and absorption;Phosphatidylinositol signaling system;Insulin signaling pathway;Colorectal cancer;Amoebiasis;Type II diabetes mellitus;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chronic myeloid leukemia;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;Measles;Non-small cell lung cancer;Melanoma;Hepatitis C;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Influenza A;Toll-like receptor signaling pathway;Pathways in cancer;Chemokine signaling pathway;Pancreatic cancer;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;Apoptosis;mTOR signaling pathway;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Glioma;Focal adhesion;VEGF signaling pathway;Osteoclast differentiation;Toxoplasmosis;Endometrial cancer;K04450//Influenza A;Alcoholism;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction
51292,0,58,2,69,69,42,17,24,60,209,62,291,GMPR2;guanosine monophosphate reductase 2,GO:0005829//cytosol;GO:1902560//GMP reductase complex,GO:0043101//purine-containing compound salvage;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0046037//GMP metabolic process;GO:0006144//purine nucleobase metabolic process,GO:0046872//metal ion binding;GO:0003920//GMP reductase activity,K00364//One carbon pool by folate;Metabolic pathways;Biosynthesis of secondary metabolites;Purine metabolism
51293,0,0,0,0,0,0,0,0,11,0,2,314,CD320;CD320 molecule,GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0001558//regulation of cell growth;GO:0009235//cobalamin metabolic process;GO:0006766//vitamin metabolic process,GO:0031419//cobalamin binding;GO:0008083//growth factor activity,-
51294,0,0,0,0,0,11,25,84,13,0,30,423,PCDH12;protocadherin 12,GO:0005911//cell-cell junction;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0060711//labyrinthine layer development;GO:0008038//neuron recognition;GO:0005977//glycogen metabolic process;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
51295,0,0,0,4,1,0,5,0,0,231,0,1,ECSIT;ECSIT signalling integrator,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0005739//mitochondrion,GO:0030509//BMP signaling pathway;GO:0051341//regulation of oxidoreductase activity;GO:0001707//mesoderm formation;GO:0045087//innate immune response;GO:0055114//oxidation-reduction process,"GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H",K04405//MAPK signaling pathway
51296,0,0,0,0,0,9,0,0,15,71,19,0,"SLC15A3;solute carrier family 15 (oligopeptide transporter), member 3",GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0015833//peptide transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0015031//protein transport,GO:0015293//symporter activity,-
51297,42,0,0,0,0,13,0,0,0,0,5,0,"BPIFA1;BPI fold containing family A, member 1",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0045087//innate immune response;GO:1902305//regulation of sodium ion transmembrane transport;GO:0050891//multicellular organismal water homeostasis;GO:0050828//regulation of liquid surface tension;GO:0019731//antibacterial humoral response;GO:1900229//negative regulation of single-species biofilm formation in or on host organism,GO:0008289//lipid binding,-
51298,0,0,0,0,0,0,21,0,15,0,6,0,THEG;theg spermatid protein,GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0051131//chaperone-mediated protein complex assembly,GO:0005515//protein binding,-
51299,40,0,0,0,0,18,9,0,2,0,0,0,NRN1;neuritin 1,GO:0045202//synapse;GO:0030054//cell junction;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0031225//anchored component of membrane,GO:0007399//nervous system development,-,K12616//RNA degradation
513,0,1,0,4,0,0,15,0,0,0,14,0,"ATP5D;ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion",GO:0006754//ATP biosynthetic process;GO:0022904//respiratory electron transport chain;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process;GO:0046688//response to copper ion;GO:0006119//oxidative phosphorylation,"GO:0016887//ATPase activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0005524//ATP binding;GO:0022857//transmembrane transporter activity;GO:0005215//transporter activity;GO:0043531//ADP binding",K02134//Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease;Metabolic pathways
5130,129,60,0,0,41,0,15,1,0,0,0,0,"PCYT1A;phosphate cytidylyltransferase 1, choline, alpha",GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0042587//glycogen granule,GO:0006657//CDP-choline pathway;GO:0044281//small molecule metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process,GO:0042803//protein homodimerization activity;GO:0008289//lipid binding;GO:0004105//choline-phosphate cytidylyltransferase activity,K00968//Metabolic pathways;Phosphonate and phosphinate metabolism;Glycerophospholipid metabolism
51300,0,10,2,21,62,0,0,1,17,0,0,0,TIMMDC1;translocase of inner mitochondrial membrane domain containing 1,GO:0005730//nucleolus;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005634//nucleus,-,-,-
51301,17,0,0,0,0,0,0,0,67,0,0,0,"GCNT4;glucosaminyl (N-acetyl) transferase 4, core 2",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0042403//thyroid hormone metabolic process;GO:0060993//kidney morphogenesis;GO:0044267//cellular protein metabolic process;GO:0002121//inter-male aggressive behavior;GO:0048729//tissue morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0048872//homeostasis of number of cells;GO:0005975//carbohydrate metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,"GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity",K09663//Metabolic pathways;Mucin type O-Glycan biosynthesis
51302,0,0,0,5,0,0,0,0,52,0,0,0,"CYP39A1;cytochrome P450, family 39, subfamily A, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0055114//oxidation-reduction process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0016125//sterol metabolic process;GO:0007586//digestion;GO:0030573//bile acid catabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006707//cholesterol catabolic process,GO:0005506//iron ion binding;GO:0008396//oxysterol 7-alpha-hydroxylase activity;GO:0020037//heme binding;GO:0008387//steroid 7-alpha-hydroxylase activity;GO:0033782//24-hydroxycholesterol 7alpha-hydroxylase activity,K07439//Primary bile acid biosynthesis
51304,113,62,0,10,50,35,58,17,75,0,34,0,"ZDHHC3;zinc finger, DHHC-type containing 3",GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0018345//protein palmitoylation;GO:0006605//protein targeting,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
51305,0,0,0,0,1,0,0,0,14,0,0,0,"KCNK9;potassium channel, subfamily K, member 9",GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane,GO:0006813//potassium ion transport;GO:0090102//cochlea development;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
51306,0,19,1,20,69,35,40,0,47,0,9,0,"FAM13B;family with sequence similarity 13, member B",GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K13709//Leukocyte transendothelial migration;Focal adhesion;K05732//Regulation of actin cytoskeleton;Focal adhesion;Leukocyte transendothelial migration;K07526//Axon guidance
51307,7,1,0,5,24,24,38,22,0,0,0,0,"FAM53C;family with sequence similarity 53, member C",-,-,-,K05867//Oocyte meiosis;Progesterone-mediated oocyte maturation;Cell cycle
51308,0,0,0,0,0,0,6,58,0,0,9,0,REEP2;receptor accessory protein 2,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005881//cytoplasmic microtubule;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0071786//endoplasmic reticulum tubular network organization;GO:0008219//cell death;GO:0050916//sensory perception of sweet taste;GO:0050913//sensory perception of bitter taste;GO:0032596//protein transport into membrane raft;GO:0032386//regulation of intracellular transport,GO:0031883//taste receptor binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
51309,0,40,0,27,39,0,0,0,6,0,0,0,"ARMCX1;armadillo repeat containing, X-linked 1",GO:0016021//integral component of membrane,-,-,-
51310,49,0,0,0,0,0,0,45,19,0,0,1,"SLC22A17;solute carrier family 22, member 17",GO:0005887//integral component of plasma membrane;GO:0005774//vacuolar membrane;GO:0031301//integral component of organelle membrane,GO:0055085//transmembrane transport;GO:0007165//signal transduction;GO:0055072//iron ion homeostasis;GO:0006811//ion transport;GO:0015891//siderophore transport,GO:0022857//transmembrane transporter activity;GO:0004888//transmembrane signaling receptor activity,-
51311,0,0,0,0,0,18,0,0,12,0,0,0,TLR8;toll-like receptor 8,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0036020//endolysosome membrane;GO:0005789//endoplasmic reticulum membrane,GO:0002282//microglial cell activation involved in immune response;GO:0009615//response to virus;GO:0002224//toll-like receptor signaling pathway;GO:0045089//positive regulation of innate immune response;GO:0016064//immunoglobulin mediated immune response;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045416//positive regulation of interleukin-8 biosynthetic process;GO:0034162//toll-like receptor 9 signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0050707//regulation of cytokine secretion;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0045356//positive regulation of interferon-alpha biosynthetic process;GO:0051607//defense response to virus;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0034158//toll-like receptor 8 signaling pathway;GO:0006954//inflammatory response,GO:0003725//double-stranded RNA binding;GO:0003677//DNA binding;GO:0003727//single-stranded RNA binding;GO:0003723//RNA binding;GO:0004872//receptor activity;GO:0008144//drug binding,K10170//Toll-like receptor signaling pathway
51312,43,67,0,8,86,0,0,33,14,0,70,331,"SLC25A37;solute carrier family 25 (mitochondrial iron transporter), member 37",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0034755//iron ion transmembrane transport;GO:0044281//small molecule metabolic process;GO:0048250//mitochondrial iron ion transport;GO:0055072//iron ion homeostasis,GO:0005381//iron ion transmembrane transporter activity,-
51313,108,0,0,17,29,23,19,0,31,0,22,0,"FAM198B;family with sequence similarity 198, member B",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,-,-,-
51314,0,0,0,8,0,6,32,0,11,0,0,0,NME8;NME/NM23 family member 8,GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0006228//UTP biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0045454//cell redox homeostasis;GO:0007275//multicellular organismal development;GO:0006183//GTP biosynthetic process;GO:0007283//spermatogenesis;GO:0006241//CTP biosynthetic process,GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity,K00940//Bacterial invasion of epithelial cells;Metabolic pathways;Nitrogen metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Shigellosis;Purine metabolism
51315,0,12,0,0,16,0,0,0,0,0,0,0,KRCC1;lysine-rich coiled-coil 1,-,-,-,-
51316,0,0,0,0,0,0,0,0,21,0,0,0,PLAC8;placenta-specific 8,-,GO:0009409//response to cold;GO:0050873//brown fat cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0040015//negative regulation of multicellular organism growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process,GO:0003682//chromatin binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer
51317,28,11,1,24,47,39,0,0,10,0,0,7,PHF21A;PHD finger protein 21A,GO:0005654//nucleoplasm;GO:0000118//histone deacetylase complex,"GO:0007596//blood coagulation;GO:0006351//transcription, DNA-templated;GO:0001967//suckling behavior;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
51318,2,36,1,16,44,0,0,0,17,0,15,0,MRPL35;mitochondrial ribosomal protein L35,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
51319,116,0,1,5,42,3,58,0,24,0,0,238,RSRC1;arginine/serine-rich coiled-coil 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck,"GO:0008380//RNA splicing;GO:0006913//nucleocytoplasmic transport;GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding,-
51320,0,0,0,27,2,0,0,52,0,0,34,0,MEX3C;mex-3 RNA binding family member C,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045598//regulation of fat cell differentiation;GO:0008152//metabolic process;GO:0003415//chondrocyte hypertrophy;GO:0097009//energy homeostasis,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
51321,0,0,0,6,46,0,0,0,24,0,0,0,AMZ2;archaelysin family metallopeptidase 2,-,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
51322,0,194,1,187,378,9,2,235,55,0,96,1,WAC;WW domain containing adaptor with coiled-coil,GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005681//spliceosomal complex,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0016239//positive regulation of macroautophagy;GO:0071894//histone H2B conserved C-terminal lysine ubiquitination;GO:0006351//transcription, DNA-templated;GO:0010390//histone monoubiquitination;GO:0044783//G1 DNA damage checkpoint;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process",GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0000993//RNA polymerase II core binding,K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
51324,0,0,1,41,120,0,0,43,14,0,0,0,"SPG21;spastic paraplegia 21 (autosomal recessive, Mast syndrome)",GO:0030140//trans-Golgi network transport vesicle;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0050851//antigen receptor-mediated signaling pathway,GO:0042609//CD4 receptor binding,-
51326,42,27,38,49,31,7,53,51,9,5,21,6,ARL17A;ADP-ribosylation factor-like 17A,-,-,-,-
51329,0,43,0,19,18,0,0,0,28,0,0,0,ARL6IP4;ADP-ribosylation factor-like 6 interacting protein 4,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
5133,0,0,0,0,0,43,0,17,0,0,0,0,PDCD1;programmed cell death 1,GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0031295//T cell costimulation;GO:0006959//humoral immune response;GO:0006915//apoptotic process;GO:0007275//multicellular organismal development;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0004871//signal transducer activity,K06744//Cell adhesion molecules (CAMs);T cell receptor signaling pathway
51332,127,0,0,0,0,74,20,98,120,52,11,0,"SPTBN5;spectrin, beta, non-erythrocytic 5",GO:0008091//spectrin;GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0097381//photoreceptor disc membrane;GO:0032391//photoreceptor connecting cilium;GO:0005737//cytoplasm,GO:0051693//actin filament capping;GO:0051260//protein homooligomerization;GO:0030036//actin cytoskeleton organization;GO:0007041//lysosomal transport;GO:0007030//Golgi organization;GO:0007411//axon guidance,GO:0003779//actin binding;GO:0034452//dynactin binding;GO:0030507//spectrin binding;GO:0043621//protein self-association;GO:0032029//myosin tail binding;GO:0019894//kinesin binding;GO:0045505//dynein intermediate chain binding,K06115//Tight junction
51335,4,65,3,55,235,0,0,0,19,0,6,0,"NGRN;neugrin, neurite outgrowth associated",GO:0005634//nucleus;GO:0005576//extracellular region,GO:0030182//neuron differentiation,GO:0044822//poly(A) RNA binding,-
51337,0,0,0,0,1,0,0,0,0,0,0,0,THEM6;thioesterase superfamily member 6,GO:0005576//extracellular region,-,-,-
51338,0,0,0,0,0,0,20,0,0,0,0,0,"MS4A4A;membrane-spanning 4-domains, subfamily A, member 4A",GO:0016021//integral component of membrane,-,-,K08090//Fc epsilon RI signaling pathway;Asthma;K06466//Hematopoietic cell lineage
51339,0,0,40,0,0,32,1,0,0,126,1,0,DACT1;dishevelled-binding antagonist of beta-catenin 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030877//beta-catenin destruction complex;GO:0030054//cell junction;GO:0045202//synapse,"GO:0046329//negative regulation of JNK cascade;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035412//regulation of catenin import into nucleus;GO:2000095//regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0001702//gastrulation with mouth forming second;GO:0045600//positive regulation of fat cell differentiation;GO:0048813//dendrite morphogenesis;GO:0048619//embryonic hindgut morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0035413//positive regulation of catenin import into nucleus;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0050808//synapse organization;GO:0031647//regulation of protein stability;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1900107//regulation of nodal signaling pathway;GO:0045732//positive regulation of protein catabolic process",GO:0070097//delta-catenin binding;GO:0051018//protein kinase A binding;GO:0008013//beta-catenin binding;GO:0005080//protein kinase C binding;GO:0005515//protein binding,-
5134,0,0,2,31,15,1,0,4,47,0,0,0,PDCD2;programmed cell death 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006915//apoptotic process,GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
51340,0,2,21,35,57,11,0,0,39,75,8,0,CRNKL1;crooked neck pre-mRNA splicing factor 1,GO:0005737//cytoplasm;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0016607//nuclear speck,"GO:0000398//mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding,K12869//Spliceosome
51341,0,11,0,6,22,0,22,87,1,0,2,0,ZBTB7A;zinc finger and BTB domain containing 7A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0035035//histone acetyltransferase binding,-
51343,50,0,3,4,6,0,15,0,17,0,5,0,FZR1;fizzy/cell division cycle 20 related 1 (Drosophila),GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane,GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0008284//positive regulation of cell proliferation;GO:0051488//activation of anaphase-promoting complex activity;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045732//positive regulation of protein catabolic process;GO:0031572//G2 DNA damage checkpoint;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0070306//lens fiber cell differentiation;GO:0000278//mitotic cell cycle;GO:0090344//negative regulation of cell aging;GO:0040020//regulation of meiosis,GO:0005515//protein binding,K03364//Cell cycle;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast
51347,0,44,0,66,222,31,0,0,16,0,4,344,TAOK3;TAO kinase 3,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007095//mitotic G2 DNA damage checkpoint;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0006469//negative regulation of protein kinase activity;GO:0006281//DNA repair;GO:0046777//protein autophosphorylation;GO:0000165//MAPK cascade;GO:0043507//positive regulation of JUN kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0006468//protein phosphorylation;GO:0046329//negative regulation of JNK cascade,GO:0004674//protein serine/threonine kinase activity;GO:0016740//transferase activity;GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity;GO:0005524//ATP binding,K04429//MAPK signaling pathway
51348,0,0,0,0,0,0,0,0,35,0,0,0,"KLRF1;killer cell lectin-like receptor subfamily F, member 1",GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0007166//cell surface receptor signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0032393//MHC class I receptor activity;GO:0030246//carbohydrate binding,-
51350,0,0,0,0,0,20,0,0,0,0,0,0,KRT76;keratin 76,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0045095//keratin filament;GO:0005634//nucleus,GO:0007010//cytoskeleton organization,GO:0005198//structural molecule activity,-
51351,0,0,21,0,26,0,0,0,44,0,0,0,ZNF117;zinc finger protein 117,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
5136,0,0,0,14,11,9,43,0,0,0,0,0,"PDE1A;phosphodiesterase 1A, calmodulin-dependent",GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005829//cytosol,GO:0034391//regulation of smooth muscle cell apoptotic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0046069//cGMP catabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0006198//cAMP catabolic process;GO:0007202//activation of phospholipase C activity;GO:0048660//regulation of smooth muscle cell proliferation;GO:0007596//blood coagulation,"GO:0046872//metal ion binding;GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0030553//cGMP binding;GO:0048101//calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity;GO:0005516//calmodulin binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K13755//Morphine addiction;Taste transduction;Purine metabolism;Calcium signaling pathway;Olfactory transduction
51360,0,0,0,0,7,0,11,0,51,1,0,0,"MBTPS2;membrane-bound transcription factor peptidase, site 2",GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0044281//small molecule metabolic process;GO:0008203//cholesterol metabolic process;GO:0006508//proteolysis;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process,GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity,K07765//Protein processing in endoplasmic reticulum
51361,0,30,0,31,185,13,25,0,72,85,0,0,HOOK1;hook microtubule-tethering protein 1,GO:0005874//microtubule;GO:0030897//HOPS complex;GO:0070695//FHF complex,GO:0008333//endosome to lysosome transport;GO:0045022//early endosome to late endosome transport;GO:0007040//lysosome organization;GO:0007286//spermatid development;GO:0007275//multicellular organismal development;GO:0007032//endosome organization;GO:0015031//protein transport,GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K12478//Phagosome;Endocytosis;Tuberculosis
51362,196,65,0,23,61,0,22,0,51,0,1,0,CDC40;cell division cycle 40,GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome,"GO:0031124//mRNA 3'-end processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0006406//mRNA export from nucleus",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12816//Spliceosome
51363,94,0,0,3,1,0,46,10,23,0,0,0,CHST15;carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0019319//hexose biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process,GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0050659//N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity,K08106//Glycosaminoglycan biosynthesis - chondroitin sulfate
51364,0,0,0,0,0,12,0,33,18,0,5,0,"ZMYND10;zinc finger, MYND-type containing 10",GO:0034451//centriolar satellite;GO:0005737//cytoplasm,GO:0036158//outer dynein arm assembly;GO:0036159//inner dynein arm assembly;GO:0044458//motile cilium assembly,GO:0005515//protein binding;GO:0046872//metal ion binding,-
51365,0,0,0,0,0,0,17,0,8,0,0,0,PLA1A;phospholipase A1 member A,GO:0070062//extracellular vesicular exosome,GO:0006629//lipid metabolic process;GO:0016042//lipid catabolic process;GO:0006658//phosphatidylserine metabolic process,GO:0008970//phosphatidylcholine 1-acylhydrolase activity,-
51366,0,20,0,52,158,88,52,0,23,0,10,0,UBR5;ubiquitin protein ligase E3 component n-recognin 5,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0050847//progesterone receptor signaling pathway;GO:2000780//negative regulation of double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0006281//DNA repair;GO:0000209//protein polyubiquitination;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:0008283//cell proliferation;GO:0035413//positive regulation of catenin import into nucleus",GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0034450//ubiquitin-ubiquitin ligase activity;GO:0043130//ubiquitin binding;GO:0003723//RNA binding,K10593//Ubiquitin mediated proteolysis
51367,0,28,0,6,31,0,0,0,8,0,0,0,"POP5;processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)",GO:0005655//nucleolar ribonuclease P complex,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0008033//tRNA processing",GO:0005515//protein binding;GO:0004526//ribonuclease P activity,K03537//Ribosome biogenesis in eukaryotes;RNA transport
51368,97,0,2,0,0,0,17,0,5,0,0,0,TEX264;testis expressed 264,GO:0070062//extracellular vesicular exosome,-,-,-
5137,13,0,0,0,0,0,0,0,35,0,0,371,"PDE1C;phosphodiesterase 1C, calmodulin-dependent 70kDa",GO:0005829//cytosol,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0008152//metabolic process;GO:0007165//signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007202//activation of phospholipase C activity,GO:0046872//metal ion binding;GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0005516//calmodulin binding,K13755//Taste transduction;Morphine addiction;Calcium signaling pathway;Olfactory transduction;Purine metabolism
51371,0,60,0,114,236,0,11,0,0,0,0,0,POMP;proteasome maturation protein,GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0031090//organelle membrane,GO:0043248//proteasome assembly,GO:0005515//protein binding,K11599//Proteasome
51372,0,24,1,13,15,0,0,0,0,0,0,0,TMA7;translation machinery associated 7 homolog (S. cerevisiae),-,-,-,-
51373,92,0,0,19,43,0,0,0,13,1,0,0,MRPS17;mitochondrial ribosomal protein S17,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding,-
51374,0,1,0,35,0,0,28,10,18,0,3,0,ATRAID;all-trans retinoic acid-induced differentiation factor,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope,GO:0033689//negative regulation of osteoblast proliferation;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0030501//positive regulation of bone mineralization;GO:0045669//positive regulation of osteoblast differentiation;GO:2000599//negative regulation of cyclin catabolic process,GO:0005515//protein binding,-
51375,0,0,0,9,0,3,0,0,9,0,0,63,SNX7;sorting nexin 7,GO:0030659//cytoplasmic vesicle membrane;GO:0005768//endosome,GO:0006915//apoptotic process;GO:0006886//intracellular protein transport,GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K08545//MAPK signaling pathway - fly
51377,5,775,67,758,1461,0,136,764,178,0,1013,0,UCHL5;ubiquitin carboxyl-terminal hydrolase L5,GO:0005829//cytosol;GO:0031011//Ino80 complex;GO:0005634//nucleus;GO:0000502//proteasome complex,"GO:0061136//regulation of proteasomal protein catabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030901//midbrain development;GO:0006355//regulation of transcription, DNA-templated;GO:0048853//forebrain morphogenesis;GO:0006281//DNA repair;GO:0016579//protein deubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006310//DNA recombination;GO:0021670//lateral ventricle development;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0010951//negative regulation of endopeptidase activity",GO:0070628//proteasome binding;GO:0004866//endopeptidase inhibitor activity;GO:0008242//omega peptidase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004843//ubiquitin-specific protease activity,-
51378,87,0,0,0,18,9,7,72,15,1,0,640,ANGPT4;angiopoietin 4,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0050900//leukocyte migration;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071456//cellular response to hypoxia;GO:0001525//angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0016525//negative regulation of angiogenesis;GO:0001935//endothelial cell proliferation;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0043066//negative regulation of apoptotic process;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0010595//positive regulation of endothelial cell migration;GO:0007596//blood coagulation,GO:0030971//receptor tyrosine kinase binding;GO:0030297//transmembrane receptor protein tyrosine kinase activator activity,-
51379,0,0,0,8,20,0,0,1,40,0,0,0,CRLF3;cytokine receptor-like factor 3,GO:0005737//cytoplasm,"GO:0030308//negative regulation of cell growth;GO:0046427//positive regulation of JAK-STAT cascade;GO:0000082//G1/S transition of mitotic cell cycle;GO:0071158//positive regulation of cell cycle arrest;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",-,K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
5138,0,0,0,0,5,30,0,0,50,1,9,100,"PDE2A;phosphodiesterase 2A, cGMP-stimulated",GO:0030424//axon;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,"GO:0035690//cellular response to drug;GO:0043116//negative regulation of vascular permeability;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0019933//cAMP-mediated signaling;GO:0008152//metabolic process;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0043117//positive regulation of vascular permeability;GO:0061028//establishment of endothelial barrier;GO:0046069//cGMP catabolic process;GO:0007596//blood coagulation;GO:0006626//protein targeting to mitochondrion;GO:0050729//positive regulation of inflammatory response;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0030224//monocyte differentiation;GO:0070588//calcium ion transmembrane transport;GO:0006198//cAMP catabolic process;GO:0071260//cellular response to mechanical stimulus;GO:0071321//cellular response to cGMP;GO:0030818//negative regulation of cAMP biosynthetic process;GO:0019934//cGMP-mediated signaling",GO:0004118//cGMP-stimulated cyclic-nucleotide phosphodiesterase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005262//calcium channel activity;GO:0042803//protein homodimerization activity;GO:0030911//TPR domain binding;GO:0008144//drug binding;GO:0030553//cGMP binding;GO:0030552//cAMP binding,K01120//Morphine addiction;Purine metabolism
51380,59,91,1,31,132,3,0,53,4,0,82,0,CSAD;cysteine sulfinic acid decarboxylase,-,GO:0042412//taurine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0044281//small molecule metabolic process;GO:0000098//sulfur amino acid catabolic process,GO:0030170//pyridoxal phosphate binding;GO:0004782//sulfinoalanine decarboxylase activity,K01594//Metabolic pathways;Taurine and hypotaurine metabolism
51382,0,22,0,42,90,25,0,11,17,0,0,0,"ATP6V1D;ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D",GO:0070062//extracellular vesicular exosome;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0005929//cilium;GO:0005765//lysosomal membrane;GO:0005813//centrosome,GO:0006879//cellular iron ion homeostasis;GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0042384//cilium assembly;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0061512//protein localization to cilium;GO:0015992//proton transport,"GO:0005515//protein binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K02149//Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Metabolic pathways;Oxidative phosphorylation;Synaptic vesicle cycle;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion
51384,0,0,0,0,0,0,0,0,8,0,0,0,"WNT16;wingless-type MMTV integration site family, member 16",GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0045165//cell fate commitment;GO:0016055//Wnt signaling pathway;GO:0003408//optic cup formation involved in camera-type eye development;GO:0030216//keratinocyte differentiation;GO:0090399//replicative senescence;GO:0043616//keratinocyte proliferation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0090403//oxidative stress-induced premature senescence;GO:0030182//neuron differentiation;GO:0046330//positive regulation of JNK cascade;GO:0010628//positive regulation of gene expression;GO:0046849//bone remodeling;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0060548//negative regulation of cell death,GO:0005109//frizzled binding,K01558//HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Hedgehog signaling pathway;Melanogenesis;Transcriptional misregulation in cancer;Basal cell carcinoma
51385,0,56,0,14,31,34,27,0,8,0,12,0,ZNF589;zinc finger protein 589,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
51386,0,112,2,147,378,0,4,0,19,0,0,0,"EIF3L;eukaryotic translation initiation factor 3, subunit L",GO:0005654//nucleoplasm;GO:0001650//fibrillar center;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0016020//membrane;GO:0016282//eukaryotic 43S preinitiation complex,GO:0006413//translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0006446//regulation of translational initiation,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003743//translation initiation factor activity,-
51388,0,10,13,6,76,15,20,0,21,0,76,0,"NIP7;NIP7, nucleolar pre-rRNA processing protein",GO:0005730//nucleolus,GO:0042255//ribosome assembly,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
51389,97,1,0,22,46,18,1,0,47,131,0,0,RWDD1;RWD domain containing 1,-,-,GO:0005515//protein binding,K08860//Epstein-Barr virus infection;Influenza A;Measles;Alzheimer's disease;Hepatitis C;Herpes simplex infection;Protein processing in endoplasmic reticulum
5139,144,0,0,0,0,0,0,75,38,0,21,0,"PDE3A;phosphodiesterase 3A, cGMP-inhibited",GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0016101//diterpenoid metabolic process;GO:0060282//positive regulation of oocyte development;GO:0051591//response to cAMP;GO:0019934//cGMP-mediated signaling;GO:0071321//cellular response to cGMP;GO:0040020//regulation of meiosis;GO:0006198//cAMP catabolic process;GO:0007596//blood coagulation;GO:0043117//positive regulation of vascular permeability;GO:0006629//lipid metabolic process;GO:0042493//response to drug;GO:0043066//negative regulation of apoptotic process;GO:0019933//cAMP-mediated signaling;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0043116//negative regulation of vascular permeability;GO:0001556//oocyte maturation,"GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0004119//cGMP-inhibited cyclic-nucleotide phosphodiesterase activity;GO:0030552//cAMP binding;GO:0046872//metal ion binding",K13296//Purine metabolism;Progesterone-mediated oocyte maturation;Morphine addiction;Insulin signaling pathway
51390,0,0,0,0,0,0,0,0,72,0,0,0,AIG1;androgen-induced 1,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,-
51393,0,0,0,0,0,15,0,0,35,0,25,0,"TRPV2;transient receptor potential cation channel, subfamily V, member 2",GO:0005887//integral component of plasma membrane;GO:0032584//growth cone membrane;GO:0044297//cell body;GO:0044295//axonal growth cone;GO:0009986//cell surface;GO:0042470//melanosome;GO:0012505//endomembrane system;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0045773//positive regulation of axon extension;GO:0009266//response to temperature stimulus;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0090280//positive regulation of calcium ion import;GO:0009408//response to heat;GO:0007600//sensory perception,GO:0005262//calcium channel activity;GO:0005216//ion channel activity;GO:0005261//cation channel activity;GO:0015075//ion transmembrane transporter activity,-
51397,0,15,0,28,96,36,0,3,9,0,0,0,COMMD10;COMM domain containing 10,-,-,GO:0005515//protein binding,-
51398,0,103,50,85,103,0,0,58,25,0,210,0,WDR83OS;WD repeat domain 83 opposite strand,GO:0016021//integral component of membrane,-,-,-
51399,0,77,0,38,67,0,0,0,0,0,93,0,TRAPPC4;trafficking protein particle complex 4,GO:0008021//synaptic vesicle;GO:0005783//endoplasmic reticulum;GO:0005801//cis-Golgi network;GO:0045202//synapse;GO:0005795//Golgi stack;GO:0030425//dendrite;GO:0030008//TRAPP complex,GO:0016358//dendrite development;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0030198//extracellular matrix organization,GO:0005515//protein binding,-
514,0,0,0,9,53,0,0,0,23,0,0,0,"ATP5E;ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit","GO:0000275//mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);GO:0005759//mitochondrial matrix;GO:0005753//mitochondrial proton-transporting ATP synthase complex",GO:0022904//respiratory electron transport chain;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process,"GO:0022857//transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0016887//ATPase activity;GO:0046961//proton-transporting ATPase activity, rotational mechanism",K02135//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
5140,0,0,0,0,10,62,29,0,23,0,3,0,"PDE3B;phosphodiesterase 3B, cGMP-inhibited",GO:0032045//guanyl-nucleotide exchange factor complex;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,GO:0007596//blood coagulation;GO:0032869//cellular response to insulin stimulus;GO:0050796//regulation of insulin secretion;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0007162//negative regulation of cell adhesion;GO:0006198//cAMP catabolic process;GO:0008286//insulin receptor signaling pathway;GO:0050995//negative regulation of lipid catabolic process;GO:0031018//endocrine pancreas development;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0042593//glucose homeostasis;GO:0016525//negative regulation of angiogenesis;GO:0001525//angiogenesis,"GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0043422//protein kinase B binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004119//cGMP-inhibited cyclic-nucleotide phosphodiesterase activity",K13296//Progesterone-mediated oocyte maturation;Purine metabolism;Insulin signaling pathway;Morphine addiction
51400,0,0,0,16,105,16,30,0,5,0,0,0,PPME1;protein phosphatase methylesterase 1,-,GO:0043086//negative regulation of catalytic activity;GO:0006482//protein demethylation;GO:0050790//regulation of catalytic activity,GO:0004864//protein phosphatase inhibitor activity;GO:0019903//protein phosphatase binding;GO:0051721//protein phosphatase 2A binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0051722//protein C-terminal methylesterase activity,-
51406,0,0,0,18,77,0,14,0,14,0,0,0,"NOL7;nucleolar protein 7, 27kDa",GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
51409,212,0,0,4,0,0,0,15,55,0,0,0,HEMK1;HemK methyltransferase family member 1,GO:0005739//mitochondrion,GO:0006479//protein methylation;GO:0006306//DNA methylation,GO:0003677//DNA binding;GO:0008276//protein methyltransferase activity;GO:0008170//N-methyltransferase activity,K00599//Polycyclic aromatic hydrocarbon degradation;Lipopolysaccharide biosynthesis;Microbial metabolism in diverse environments;Histidine metabolism;Tyrosine metabolism;Metabolic pathways
5141,0,0,0,0,14,0,0,71,82,0,2,0,"PDE4A;phosphodiesterase 4A, cAMP-specific",GO:0016020//membrane;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0048471//perinuclear region of cytoplasm,GO:0006198//cAMP catabolic process;GO:0043949//regulation of cAMP-mediated signaling;GO:0007165//signal transduction;GO:0035690//cellular response to drug;GO:0010738//regulation of protein kinase A signaling;GO:0007608//sensory perception of smell,"GO:0046872//metal ion binding;GO:0030552//cAMP binding;GO:0005515//protein binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K01120//Morphine addiction;Purine metabolism
51411,0,0,0,0,0,0,0,0,70,0,0,0,BIN2;bridging integrator 2,GO:0001891//phagocytic cup;GO:0030054//cell junction;GO:0002102//podosome;GO:0005938//cell cortex;GO:0042995//cell projection,"GO:0006911//phagocytosis, engulfment;GO:0097320//membrane tubulation;GO:0071800//podosome assembly;GO:0060326//cell chemotaxis",GO:0005543//phospholipid binding;GO:0005515//protein binding,K12562//Fc gamma R-mediated phagocytosis
51412,0,0,0,0,0,0,26,52,38,54,14,0,ACTL6B;actin-like 6B,GO:0016514//SWI/SNF complex;GO:0005634//nucleus;GO:0071565//nBAF complex;GO:0005730//nucleolus,"GO:0007399//nervous system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated",GO:0005200//structural constituent of cytoskeleton;GO:0003713//transcription coactivator activity,-
5142,0,50,0,11,53,0,20,0,12,0,0,0,"PDE4B;phosphodiesterase 4B, cAMP-specific",GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005891//voltage-gated calcium channel complex;GO:0030018//Z disc,GO:0001780//neutrophil homeostasis;GO:0086004//regulation of cardiac muscle cell contraction;GO:0071872//cellular response to epinephrine stimulus;GO:0035690//cellular response to drug;GO:0030593//neutrophil chemotaxis;GO:1901898//negative regulation of relaxation of cardiac muscle;GO:0006198//cAMP catabolic process;GO:0032743//positive regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:0032729//positive regulation of interferon-gamma production;GO:0071222//cellular response to lipopolysaccharide;GO:0050900//leukocyte migration,"GO:0044325//ion channel binding;GO:0030552//cAMP binding;GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K01120//Morphine addiction;Purine metabolism
51421,0,0,0,5,0,0,0,71,120,162,0,0,AMOTL2;angiomotin like 2,GO:0005829//cytosol;GO:0005923//tight junction;GO:0055037//recycling endosome;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane,GO:0016055//Wnt signaling pathway;GO:0035329//hippo signaling,GO:0042802//identical protein binding;GO:0005515//protein binding,K06104//Tight junction
51422,10,0,0,0,10,0,0,0,45,0,27,0,"PRKAG2;protein kinase, AMP-activated, gamma 2 non-catalytic subunit",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0031588//AMP-activated protein kinase complex,GO:0006469//negative regulation of protein kinase activity;GO:0044281//small molecule metabolic process;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0044255//cellular lipid metabolic process;GO:0046320//regulation of fatty acid oxidation;GO:0042304//regulation of fatty acid biosynthetic process;GO:0006853//carnitine shuttle;GO:0035556//intracellular signal transduction;GO:0019217//regulation of fatty acid metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0007050//cell cycle arrest;GO:0016126//sterol biosynthetic process;GO:0006633//fatty acid biosynthetic process;GO:0006110//regulation of glycolytic process;GO:0006754//ATP biosynthetic process;GO:0008286//insulin receptor signaling pathway;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0061024//membrane organization;GO:0005977//glycogen metabolic process;GO:0046324//regulation of glucose import;GO:0006112//energy reserve metabolic process,GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0043531//ADP binding;GO:0030295//protein kinase activator activity;GO:0016208//AMP binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0008607//phosphorylase kinase regulator activity;GO:0005524//ATP binding;GO:0019901//protein kinase binding,K07200//Adipocytokine signaling pathway;Hypertrophic cardiomyopathy (HCM);Insulin signaling pathway
51426,0,0,0,13,15,0,10,0,0,0,0,0,POLK;polymerase (DNA directed) kappa,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair",GO:0046872//metal ion binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003684//damaged DNA binding,K03511//Fanconi anemia pathway
51427,66,0,0,7,0,20,1,58,33,0,0,0,ZNF107;zinc finger protein 107,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K15464//Legionellosis;K13962//Gastric acid secretion
51428,0,0,0,0,11,15,0,41,18,0,1,0,DDX41;DEAD (Asp-Glu-Ala-Asp) box polypeptide 41,GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,"GO:0007275//multicellular organismal development;GO:0000398//mRNA splicing, via spliceosome;GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035458//cellular response to interferon-beta;GO:0006396//RNA processing;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004386//helicase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005524//ATP binding,-
51429,91,1,0,49,88,11,0,0,16,0,1,0,SNX9;sorting nexin 9,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0030136//clathrin-coated vesicle;GO:0001726//ruffle;GO:0030659//cytoplasmic vesicle membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network,GO:0043547//positive regulation of GTPase activity;GO:0006886//intracellular protein transport;GO:0007067//mitotic nuclear division;GO:0000281//mitotic cytokinesis;GO:0032461//positive regulation of protein oligomerization;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0036089//cleavage furrow formation;GO:0016197//endosomal transport;GO:0060988//lipid tube assembly;GO:0006897//endocytosis;GO:0006898//receptor-mediated endocytosis,GO:0005545//1-phosphatidylinositol binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity,-
5143,0,0,0,0,0,9,19,3,37,0,13,0,"PDE4C;phosphodiesterase 4C, cAMP-specific",GO:0072372//primary cilium;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0006198//cAMP catabolic process;GO:0007165//signal transduction,"GO:0046872//metal ion binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K01120//Morphine addiction;Purine metabolism
51430,21,0,30,11,18,24,0,0,101,0,36,0,SUCO;SUN domain containing ossification factor,GO:0030867//rough endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005791//rough endoplasmic reticulum,GO:0032967//positive regulation of collagen biosynthetic process;GO:0001503//ossification;GO:0007275//multicellular organismal development;GO:0045669//positive regulation of osteoblast differentiation;GO:0046850//regulation of bone remodeling,-,-
51433,0,27,1,12,2,37,21,72,85,0,7,0,ANAPC5;anaphase promoting complex subunit 5,GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle,GO:0019903//protein phosphatase binding,K03352//Meiosis - yeast;HTLV-I infection;Oocyte meiosis;Cell cycle;Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis
51434,0,0,0,12,33,28,9,0,52,0,25,0,ANAPC7;anaphase promoting complex subunit 7,GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle,GO:0019903//protein phosphatase binding,K03354//Oocyte meiosis;HTLV-I infection;Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis
51435,2,0,0,0,0,0,0,0,1,0,0,1259,"SCARA3;scavenger receptor class A, member 3",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005581//collagen trimer;GO:0005789//endoplasmic reticulum membrane,GO:0006898//receptor-mediated endocytosis;GO:0009650//UV protection;GO:0006979//response to oxidative stress,GO:0005044//scavenger receptor activity,K10062//Phagosome
51438,0,0,0,0,0,0,0,0,18,0,0,0,"MAGEC2;melanoma antigen family C, 2",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0044257//cellular protein catabolic process,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
51439,0,15,0,8,41,0,13,0,33,0,0,0,"FAM8A1;family with sequence similarity 8, member A1",GO:0016021//integral component of membrane,-,-,-
5144,174,117,19,64,93,45,39,64,56,242,52,0,"PDE4D;phosphodiesterase 4D, cAMP-specific",GO:0016020//membrane;GO:0005829//cytosol;GO:0005815//microtubule organizing center;GO:0005891//voltage-gated calcium channel complex;GO:0016324//apical plasma membrane;GO:0034704//calcium channel complex,GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0061028//establishment of endothelial barrier;GO:0032729//positive regulation of interferon-gamma production;GO:0032754//positive regulation of interleukin-5 production;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0010469//regulation of receptor activity;GO:0035264//multicellular organism growth;GO:0086004//regulation of cardiac muscle cell contraction;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0071872//cellular response to epinephrine stimulus;GO:0030593//neutrophil chemotaxis;GO:0071875//adrenergic receptor signaling pathway;GO:1901898//negative regulation of relaxation of cardiac muscle;GO:0019933//cAMP-mediated signaling;GO:0007568//aging;GO:0045822//negative regulation of heart contraction;GO:0006939//smooth muscle contraction;GO:0071222//cellular response to lipopolysaccharide;GO:0071320//cellular response to cAMP;GO:0086024//adrenergic receptor signaling pathway involved in positive regulation of heart rate;GO:0006198//cAMP catabolic process;GO:0002027//regulation of heart rate;GO:0032743//positive regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway,"GO:0030552//cAMP binding;GO:0031625//ubiquitin protein ligase binding;GO:0051117//ATPase binding;GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0097110//scaffold protein binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0031698//beta-2 adrenergic receptor binding",K01120//Purine metabolism;Morphine addiction
51440,0,0,0,0,0,0,16,0,0,0,0,0,HPCAL4;hippocalcin like 4,GO:0005622//intracellular,GO:0007417//central nervous system development;GO:0007165//signal transduction,GO:0005509//calcium ion binding;GO:0008022//protein C-terminus binding;GO:0005246//calcium channel regulator activity;GO:0019904//protein domain specific binding,K13764//Phototransduction
51441,0,0,1,13,27,0,0,3,11,0,8,0,"YTHDF2;YTH domain family, member 2",GO:0000932//cytoplasmic mRNA processing body,GO:0006959//humoral immune response;GO:0043488//regulation of mRNA stability,GO:0044822//poly(A) RNA binding;GO:1990247//N6-methyladenosine-containing RNA binding,-
51444,249,27,0,3,73,29,18,0,15,0,11,0,"RNF138;ring finger protein 138, E3 ubiquitin protein ligase",GO:0005634//nucleus,GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0016874//ligase activity,-
51447,0,32,0,0,29,82,27,0,27,0,0,0,IP6K2;inositol hexakisphosphate kinase 2,GO:0045111//intermediate filament cytoskeleton;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0019221//cytokine-mediated signaling pathway;GO:0046854//phosphatidylinositol phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0030308//negative regulation of cell growth;GO:0006817//phosphate ion transport;GO:0044281//small molecule metabolic process;GO:0060337//type I interferon signaling pathway,"GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0005524//ATP binding;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity",-
51449,0,0,0,10,21,8,0,0,24,0,0,0,PCYOX1;prenylcysteine oxidase 1,GO:0005764//lysosome;GO:0034361//very-low-density lipoprotein particle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030327//prenylated protein catabolic process;GO:0030328//prenylcysteine catabolic process;GO:0055114//oxidation-reduction process;GO:1902476//chloride transmembrane transport,GO:0008555//chloride-transporting ATPase activity;GO:0001735//prenylcysteine oxidase activity,K05906//Terpenoid backbone biosynthesis
5145,49,0,0,0,1,0,12,77,158,0,0,0,"PDE6A;phosphodiesterase 6A, cGMP-specific, rod, alpha",GO:0005886//plasma membrane;GO:0097381//photoreceptor disc membrane,"GO:0060041//retina development in camera-type eye;GO:0007603//phototransduction, visible light;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0051480//cytosolic calcium ion homeostasis;GO:0007601//visual perception;GO:0046037//GMP metabolic process","GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity",K08718//Phototransduction;Purine metabolism
51450,0,0,0,0,0,13,0,0,24,0,0,0,PRRX2;paired related homeobox 2,GO:0005634//nucleus,"GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0045880//positive regulation of smoothened signaling pathway;GO:0051216//cartilage development;GO:0048844//artery morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0042474//middle ear morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
51451,0,1,0,1,24,0,0,0,9,0,9,0,LCMT1;leucine carboxyl methyltransferase 1,GO:0005829//cytosol,GO:0042981//regulation of apoptotic process;GO:0006464//cellular protein modification process;GO:0006481//C-terminal protein methylation;GO:0031333//negative regulation of protein complex assembly;GO:0010906//regulation of glucose metabolic process;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint;GO:0006479//protein methylation,GO:0003880//protein C-terminal carboxyl O-methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0005515//protein binding,-
51454,0,417,34,259,678,0,35,235,41,133,610,305,"GULP1;GULP, engulfment adaptor PTB domain containing 1",GO:0005737//cytoplasm,"GO:0007165//signal transduction;GO:0006869//lipid transport;GO:0006915//apoptotic process;GO:0006911//phagocytosis, engulfment",GO:0004871//signal transducer activity,K12474//Endocytosis
51455,0,0,25,38,55,0,10,50,1,0,0,0,"REV1;REV1, polymerase (DNA directed)",GO:0005654//nucleoplasm,GO:0006261//DNA-dependent DNA replication;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0009411//response to UV;GO:0042276//error-prone translesion synthesis,GO:0017125//deoxycytidyl transferase activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0003684//damaged DNA binding,K03515//Fanconi anemia pathway
51458,0,0,0,0,0,0,42,100,57,28,13,519,"RHCG;Rh family, C glycoprotein",GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane,GO:0070634//transepithelial ammonium transport;GO:0006873//cellular ion homeostasis;GO:0006885//regulation of pH;GO:0042592//homeostatic process;GO:0015837//amine transport;GO:0072488//ammonium transmembrane transport;GO:0055085//transmembrane transport;GO:0030855//epithelial cell differentiation,GO:0030506//ankyrin binding;GO:0008519//ammonium transmembrane transporter activity,-
5146,0,0,0,0,0,26,0,0,17,0,21,0,"PDE6C;phosphodiesterase 6C, cGMP-specific, cone, alpha prime",GO:0005886//plasma membrane,"GO:0007603//phototransduction, visible light;GO:0008152//metabolic process;GO:0007601//visual perception;GO:0046549//retinal cone cell development","GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0046872//metal ion binding;GO:0030553//cGMP binding",K13757//Purine metabolism
51460,114,20,0,0,28,19,30,0,40,0,0,0,SFMBT1;Scm-like with four mbt domains 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0016568//chromatin modification;GO:0048635//negative regulation of muscle organ development;GO:0007283//spermatogenesis",GO:0003714//transcription corepressor activity;GO:0042393//histone binding;GO:0005515//protein binding,-
51463,0,0,0,0,1,0,23,0,10,0,0,203,GPR89B;G protein-coupled receptor 89B,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0034765//regulation of ion transmembrane transport;GO:0015031//protein transport;GO:0006811//ion transport,GO:0005244//voltage-gated ion channel activity,-
51465,0,301,1,334,1018,0,18,0,51,0,18,0,"UBE2J1;ubiquitin-conjugating enzyme E2, J1",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0016567//protein ubiquitination,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K10578//Protein processing in endoplasmic reticulum;Parkinson's disease;Ubiquitin mediated proteolysis
51466,0,1,41,7,27,36,0,0,77,0,9,0,EVL;Enah/Vasp-like,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0016020//membrane,GO:0010633//negative regulation of epithelial cell migration;GO:0007166//cell surface receptor signaling pathway;GO:0007015//actin filament organization;GO:1900028//negative regulation of ruffle assembly;GO:0009887//organ morphogenesis;GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0051496//positive regulation of stress fiber assembly;GO:0051289//protein homotetramerization;GO:0030838//positive regulation of actin filament polymerization;GO:0008154//actin polymerization or depolymerization,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0003779//actin binding;GO:0005522//profilin binding,K05746//Regulation of actin cytoskeleton
5147,0,0,0,16,30,32,0,0,21,0,0,0,"PDE6D;phosphodiesterase 6D, cGMP-specific, rod, delta",GO:0031410//cytoplasmic vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol,GO:0008152//metabolic process;GO:0007601//visual perception;GO:0033124//regulation of GTP catabolic process;GO:0050896//response to stimulus;GO:0043086//negative regulation of catalytic activity,"GO:0005095//GTPase inhibitor activity;GO:0005515//protein binding;GO:0017137//Rab GTPase binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity",K13758//Purine metabolism
51471,0,0,0,8,0,0,0,0,1,0,9,0,"NAT8B;N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0016021//integral component of membrane,GO:0001702//gastrulation with mouth forming second;GO:0010628//positive regulation of gene expression;GO:0050435//beta-amyloid metabolic process;GO:0043066//negative regulation of apoptotic process,"GO:0008080//N-acetyltransferase activity;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0005515//protein binding",-
51473,0,0,0,0,0,11,0,0,19,0,22,0,DCDC2;doublecortin domain containing 2,-,GO:0035556//intracellular signal transduction;GO:0006968//cellular defense response;GO:0001764//neuron migration;GO:0048813//dendrite morphogenesis;GO:0008542//visual learning,-,-
51474,0,42,0,24,79,9,31,0,25,198,0,1,LIMA1;LIM domain and actin binding 1,GO:0001725//stress fiber;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton,GO:0031529//ruffle organization;GO:0051017//actin filament bundle assembly;GO:0030835//negative regulation of actin filament depolymerization,GO:0003785//actin monomer binding;GO:0008270//zinc ion binding;GO:0051015//actin filament binding;GO:0005515//protein binding,-
51477,77,24,0,16,66,18,4,69,22,0,37,0,ISYNA1;inositol-3-phosphate synthase 1,GO:0005829//cytosol,GO:0006021//inositol biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process,GO:0004512//inositol-3-phosphate synthase activity,K01858//Metabolic pathways;Streptomycin biosynthesis;Biosynthesis of secondary metabolites;Inositol phosphate metabolism
51478,0,18,0,0,0,0,26,0,33,0,0,0,HSD17B7;hydroxysteroid (17-beta) dehydrogenase 7,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0006703//estrogen biosynthetic process,GO:0000253//3-keto sterol reductase activity;GO:0005148//prolactin receptor binding;GO:0004303//estradiol 17-beta-dehydrogenase activity,K13373//Steroid hormone biosynthesis;Metabolic pathways;Steroid biosynthesis
51479,0,35,0,31,179,24,6,14,51,3,81,0,ANKFY1;ankyrin repeat and FYVE domain containing 1,GO:0044354//macropinosome;GO:0030904//retromer complex;GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome,"GO:0042147//retrograde transport, endosome to Golgi;GO:0048549//positive regulation of pinocytosis;GO:0032439//endosome localization;GO:0090160//Golgi to lysosome transport",GO:1901981//phosphatidylinositol phosphate binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0017137//Rab GTPase binding,-
5148,0,0,0,0,0,0,0,79,26,0,0,0,"PDE6G;phosphodiesterase 6G, cGMP-specific, rod, gamma",GO:0097381//photoreceptor disc membrane;GO:0005886//plasma membrane,"GO:0000187//activation of MAPK activity;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0043086//negative regulation of catalytic activity;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light;GO:0008152//metabolic process;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0007601//visual perception","GO:0005515//protein binding;GO:0030553//cGMP binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004857//enzyme inhibitor activity",K13759//Phototransduction;Purine metabolism
51480,87,0,0,0,0,4,0,0,0,0,0,0,"VCX2;variable charge, X-linked 2",-,-,-,-
51481,0,0,0,0,0,0,0,0,1,0,0,0,"VCX3A;variable charge, X-linked 3A",GO:0005634//nucleus;GO:0005730//nucleolus,GO:0007420//brain development,-,-
51490,0,721,90,432,687,3,0,253,107,210,1573,0,C9orf114;chromosome 9 open reading frame 114,-,-,GO:0044822//poly(A) RNA binding,-
51491,10,0,0,5,27,41,0,0,0,0,0,0,NOP16;NOP16 nucleolar protein,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,-,GO:0044822//poly(A) RNA binding,-
51493,0,0,0,17,57,0,0,74,8,71,3,0,"RTCB;RNA 2',3'-cyclic phosphate and 5'-OH ligase",GO:0072669//tRNA-splicing ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001890//placenta development;GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0001701//in utero embryonic development",GO:0017166//vinculin binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0003972//RNA ligase (ATP) activity,-
51495,0,0,0,11,0,10,26,32,12,0,0,0,PTPLAD1;protein tyrosine phosphatase-like A domain containing 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005925//focal adhesion,GO:0043547//positive regulation of GTPase activity;GO:0007266//Rho protein signal transduction;GO:0016601//Rac protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007257//activation of JUN kinase activity;GO:0006633//fatty acid biosynthetic process,GO:0005515//protein binding;GO:0016829//lyase activity;GO:0005096//GTPase activator activity,K10703//Fatty acid elongation;Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites
51496,0,0,0,9,52,15,12,44,63,0,0,0,"CTDSPL2;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2",-,GO:0016311//dephosphorylation,GO:0004721//phosphoprotein phosphatase activity,-
51497,67,1,0,11,27,0,31,2,9,0,9,0,NELFCD;negative elongation factor complex member C/D,GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0032021//NELF complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0010467//gene expression",GO:0005515//protein binding,-
51499,0,0,0,13,10,0,0,0,0,0,0,0,TRIAP1;TP53 regulated inhibitor of apoptosis 1,GO:0048471//perinuclear region of cytoplasm;GO:0043234//protein complex;GO:0005758//mitochondrial intermembrane space;GO:0005739//mitochondrion,"GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0097035//regulation of membrane lipid distribution;GO:0034644//cellular response to UV;GO:0043066//negative regulation of apoptotic process;GO:0015914//phospholipid transport;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001140//positive regulation of phospholipid transport;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0030330//DNA damage response, signal transduction by p53 class mediator",GO:0005515//protein binding;GO:0002039//p53 binding;GO:1990050//phosphatidic acid transporter activity,-
515,0,165,34,34,263,22,0,424,19,0,169,0,"ATP5F1;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005759//mitochondrial matrix;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome",GO:0022904//respiratory electron transport chain;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0044237//cellular metabolic process;GO:0015986//ATP synthesis coupled proton transport;GO:0042776//mitochondrial ATP synthesis coupled proton transport,"GO:0022857//transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0016887//ATPase activity;GO:0005515//protein binding",K02127//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
5150,242,53,140,162,215,29,32,28,58,0,151,0,PDE7A;phosphodiesterase 7A,GO:0005829//cytosol,GO:0007165//signal transduction;GO:0006198//cAMP catabolic process,"GO:0046872//metal ion binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K01120//Purine metabolism;Morphine addiction
51501,0,0,0,0,0,14,0,0,0,110,0,0,C11orf73;chromosome 11 open reading frame 73,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0030054//cell junction;GO:0005634//nucleus,GO:0015031//protein transport;GO:0007030//Golgi organization;GO:0006606//protein import into nucleus;GO:0034605//cellular response to heat;GO:0030324//lung development,GO:0008565//protein transporter activity;GO:0030544//Hsp70 protein binding,-
51504,0,22,0,24,142,0,8,0,17,0,53,0,TRMT112;tRNA methyltransferase 11-2 homolog (S. cerevisiae),GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex,GO:0018364//peptidyl-glutamine methylation,GO:0005515//protein binding;GO:0008276//protein methyltransferase activity,-
51506,0,55,1,8,71,12,0,0,0,0,0,0,UFC1;ubiquitin-fold modifier conjugating enzyme 1,GO:0070062//extracellular vesicular exosome,GO:0034976//response to endoplasmic reticulum stress;GO:0071569//protein ufmylation,GO:0071568//UFM1 conjugating enzyme activity;GO:0005515//protein binding,-
51507,0,50,1,1,109,45,0,6,13,101,1,0,RTFDC1;replication termination factor 2 domain containing 1,-,-,-,-
5151,0,0,0,10,32,20,14,0,23,0,0,0,PDE8A;phosphodiesterase 8A,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0000160//phosphorelay signal transduction system;GO:0006198//cAMP catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0009187//cyclic nucleotide metabolic process","GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0046872//metal ion binding;GO:0004871//signal transducer activity",K01120//Purine metabolism;Morphine addiction
51510,0,23,1,58,22,19,0,15,12,1,0,299,CHMP5;charged multivesicular body protein 5,GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0019058//viral life cycle;GO:0016032//viral process;GO:0001919//regulation of receptor recycling;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport,GO:0005515//protein binding,K12198//Endocytosis
51512,2,0,0,0,0,15,0,24,6,96,4,0,GTSE1;G-2 and S-phase expressed 1,GO:0005881//cytoplasmic microtubule;GO:0016020//membrane,"GO:0007017//microtubule-based process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0005515//protein binding,K10129//p53 signaling pathway
51513,0,0,48,2,0,0,0,42,0,0,1,0,ETV7;ets variant 7,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,K03211//MAPK signaling pathway - fly;Dorso-ventral axis formation;Transcriptional misregulation in cancer
51514,158,0,0,0,0,39,0,0,12,204,1,87,DTL;denticleless E3 ubiquitin protein ligase homolog (Drosophila),GO:0005694//chromosome;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0043231//intracellular membrane-bounded organelle;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006513//protein monoubiquitination;GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0000209//protein polyubiquitination;GO:0009411//response to UV;GO:0031572//G2 DNA damage checkpoint;GO:0019985//translesion synthesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
51517,0,0,0,0,0,0,2,0,28,0,5,0,NCKIPSD;NCK interacting protein with SH3 domain,GO:0005829//cytosol;GO:0005882//intermediate filament;GO:0008180//COP9 signalosome,GO:0045087//innate immune response;GO:0007165//signal transduction;GO:0007010//cytoskeleton organization;GO:0006607//NLS-bearing protein import into nucleus;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0008092//cytoskeletal protein binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding,-
5152,8,31,1,7,81,0,0,0,52,101,3,0,PDE9A;phosphodiesterase 9A,GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm,GO:0008152//metabolic process;GO:0007165//signal transduction;GO:0019934//cGMP-mediated signaling;GO:0007596//blood coagulation,"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity",K13761//Purine metabolism
51520,0,119,48,70,288,35,0,0,58,0,8,537,LARS;leucyl-tRNA synthetase,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006429//leucyl-tRNA aminoacylation;GO:0006450//regulation of translational fidelity,GO:0005524//ATP binding;GO:0002161//aminoacyl-tRNA editing activity;GO:0004823//leucine-tRNA ligase activity;GO:0005515//protein binding,K01869//Cyanoamino acid metabolism;Riboflavin metabolism;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;ABC transporters
51522,0,11,0,52,32,29,0,0,22,0,0,0,TMEM14C;transmembrane protein 14C,GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane,GO:0006783//heme biosynthetic process,-,-
51523,0,22,0,0,0,0,0,61,9,0,0,0,CXXC5;CXXC finger protein 5,GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0004871//signal transducer activity,K03344//Wnt signaling pathway
51524,0,62,0,27,53,0,0,10,0,0,121,0,TMEM138;transmembrane protein 138,GO:0005774//vacuolar membrane;GO:0016021//integral component of membrane;GO:0005929//cilium,GO:0042384//cilium assembly,-,-
51526,0,0,0,1,34,0,18,0,42,0,0,0,OSER1;oxidative stress responsive serine-rich 1,-,GO:0070301//cellular response to hydrogen peroxide,-,-
51527,0,25,0,38,13,10,8,0,11,0,0,0,GSKIP;GSK3B interacting protein,GO:0005737//cytoplasm,-,-,-
51528,0,0,0,6,0,0,0,0,12,0,8,0,JKAMP;JNK1/MAPK8-associated membrane protein,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006986//response to unfolded protein;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0031625//ubiquitin protein ligase binding,-
51529,0,119,0,74,29,10,13,370,60,0,155,0,ANAPC11;anaphase promoting complex subunit 11,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex,GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity,K03358//Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;HTLV-I infection;Oocyte meiosis;Meiosis - yeast
5153,0,0,0,0,0,41,0,39,92,0,10,0,"PDE1B;phosphodiesterase 1B, calmodulin-dependent",GO:0043025//neuronal cell body;GO:0005829//cytosol,GO:0046069//cGMP catabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042428//serotonin metabolic process;GO:0045087//innate immune response;GO:0001505//regulation of neurotransmitter levels;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0007626//locomotory behavior;GO:0007202//activation of phospholipase C activity;GO:0007165//signal transduction;GO:0008542//visual learning;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001975//response to amphetamine;GO:0006198//cAMP catabolic process;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0006915//apoptotic process;GO:0030224//monocyte differentiation;GO:0007596//blood coagulation;GO:0042053//regulation of dopamine metabolic process,"GO:0004117//calmodulin-dependent cyclic-nucleotide phosphodiesterase activity;GO:0046872//metal ion binding;GO:0005516//calmodulin binding;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity;GO:0048101//calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity",K13755//Purine metabolism;Calcium signaling pathway;Olfactory transduction;Morphine addiction;Taste transduction
51530,103,3,0,0,1,0,0,43,32,0,0,0,"ZC3HC1;zinc finger, C3HC-type containing 1",GO:0005634//nucleus;GO:0031965//nuclear membrane,GO:0007067//mitotic nuclear division;GO:0016567//protein ubiquitination;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
51531,0,0,0,0,16,0,0,0,22,0,0,0,C9orf156;chromosome 9 open reading frame 156,-,GO:0016032//viral process;GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
51533,0,0,0,25,39,10,0,1,16,3,0,0,PHF7;PHD finger protein 7,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005634//nucleus,-,GO:0008270//zinc ion binding,K11421//Lysine degradation;K09188//Lysine degradation
51534,0,45,0,15,104,1,0,0,2,0,0,0,VTA1;vesicle (multivesicular body) trafficking 1,GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005829//cytosol,GO:0016032//viral process;GO:0019058//viral life cycle;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0016197//endosomal transport,GO:0005515//protein binding,K12199//Endocytosis
51535,0,59,0,17,8,105,0,0,41,0,3,0,PPHLN1;periphilin 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0031424//keratinization,GO:0044822//poly(A) RNA binding,-
51537,0,0,0,0,19,0,62,0,15,0,4,0,MTFP1;mitochondrial fission process 1,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006915//apoptotic process;GO:0000266//mitochondrial fission,-,-
51538,42,21,21,12,5,0,0,0,30,31,14,0,"ZCCHC17;zinc finger, CCHC domain containing 17",GO:0022625//cytosolic large ribosomal subunit;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K12818//Spliceosome
5154,0,0,20,0,10,0,0,0,0,1,0,0,PDGFA;platelet-derived growth factor alpha polypeptide,GO:0005576//extracellular region;GO:0000139//Golgi membrane;GO:0031093//platelet alpha granule lumen;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005902//microvillus,GO:0048015//phosphatidylinositol-mediated signaling;GO:0072124//regulation of glomerular mesangial cell proliferation;GO:0009887//organ morphogenesis;GO:0048146//positive regulation of fibroblast proliferation;GO:0001775//cell activation;GO:0030031//cell projection assembly;GO:0060683//regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0043588//skin development;GO:0001525//angiogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0010544//negative regulation of platelet activation;GO:0045087//innate immune response;GO:0001942//hair follicle development;GO:0009790//embryo development;GO:0008284//positive regulation of cell proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0002576//platelet degranulation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0050919//negative chemotaxis;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0032355//response to estradiol;GO:0048839//inner ear development;GO:0009611//response to wounding;GO:0051781//positive regulation of cell division;GO:0010035//response to inorganic substance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0030335//positive regulation of cell migration;GO:0030036//actin cytoskeleton organization;GO:0042060//wound healing;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0048286//lung alveolus development;GO:0043406//positive regulation of MAP kinase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0042493//response to drug;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0007267//cell-cell signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0031954//positive regulation of protein autophosphorylation;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:2000278//regulation of DNA biosynthetic process;GO:0045740//positive regulation of DNA replication;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001666//response to hypoxia;GO:0032526//response to retinoic acid;GO:0014910//regulation of smooth muscle cell migration,GO:0005161//platelet-derived growth factor receptor binding;GO:0005518//collagen binding;GO:0008083//growth factor activity;GO:0048407//platelet-derived growth factor binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K04359//Transcriptional misregulation in cancer;Prostate cancer;Gap junction;Pathways in cancer;HTLV-I infection;Glioma;Focal adhesion;Renal cell carcinoma;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Regulation of actin cytoskeleton;Melanoma
51542,2,15,0,22,82,38,0,0,36,0,1,0,VPS54;vacuolar protein sorting 54 homolog (S. cerevisiae),GO:0000938//GARP complex,"GO:0060052//neurofilament cytoskeleton organization;GO:0040007//growth;GO:0042147//retrograde transport, endosome to Golgi;GO:0048873//homeostasis of number of cells within a tissue;GO:0015031//protein transport;GO:0050881//musculoskeletal movement",GO:0005515//protein binding,-
51545,0,0,0,0,0,0,0,0,12,0,5,0,ZNF581;zinc finger protein 581,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
51547,0,0,0,0,1,0,0,0,4,62,0,1,SIRT7;sirtuin 7,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005731//nucleolus organizer region,GO:0007072//positive regulation of transcription on exit from mitosis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070932//histone H3 deacetylation;GO:0009303//rRNA transcription;GO:0070933//histone H4 deacetylation,GO:0003682//chromatin binding;GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0070403//NAD+ binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
51548,0,0,0,0,0,0,0,1,8,0,10,0,SIRT6;sirtuin 6,GO:0005634//nucleus;GO:0005724//nuclear telomeric heterochromatin;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0016575//histone deacetylation;GO:0006471//protein ADP-ribosylation;GO:0070932//histone H3 deacetylation;GO:0010569//regulation of double-strand break repair via homologous recombination,GO:0070403//NAD+ binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0017136//NAD-dependent histone deacetylase activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity,-
5155,68,0,0,0,0,1,0,0,15,0,5,0,PDGFB;platelet-derived growth factor beta polypeptide,GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0031093//platelet alpha granule lumen;GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0000139//Golgi membrane,"GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060445//branching involved in salivary gland morphogenesis;GO:0030036//actin cytoskeleton organization;GO:2000573//positive regulation of DNA biosynthetic process;GO:0006929//substrate-dependent cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043406//positive regulation of MAP kinase activity;GO:0032868//response to insulin;GO:1900127//positive regulation of hyaluronan biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0072264//metanephric glomerular endothelium development;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006260//DNA replication;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0060664//epithelial cell proliferation involved in salivary gland morphogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0050921//positive regulation of chemotaxis;GO:0072262//metanephric glomerular mesangial cell proliferation involved in metanephros development;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010544//negative regulation of platelet activation;GO:0008284//positive regulation of cell proliferation;GO:0072126//positive regulation of glomerular mesangial cell proliferation;GO:0060326//cell chemotaxis;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0045840//positive regulation of mitosis;GO:0030097//hemopoiesis;GO:0002548//monocyte chemotaxis;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0030168//platelet activation;GO:0032355//response to estradiol;GO:0009611//response to wounding;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0042493//response to drug;GO:0003104//positive regulation of glomerular filtration;GO:0038001//paracrine signaling;GO:0030198//extracellular matrix organization;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0031954//positive regulation of protein autophosphorylation;GO:0010512//negative regulation of phosphatidylinositol biosynthetic process;GO:0045740//positive regulation of DNA replication;GO:0090280//positive regulation of calcium ion import;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001666//response to hypoxia;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0071506//cellular response to mycophenolic acid;GO:0071363//cellular response to growth factor stimulus;GO:0072255//metanephric glomerular mesangial cell development;GO:0048514//blood vessel morphogenesis;GO:0030031//cell projection assembly;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0032147//activation of protein kinase activity;GO:0048146//positive regulation of fibroblast proliferation;GO:0030336//negative regulation of cell migration;GO:0045087//innate immune response;GO:0050918//positive chemotaxis;GO:0016049//cell growth;GO:0043410//positive regulation of MAPK cascade;GO:0007507//heart development;GO:0014911//positive regulation of smooth muscle cell migration;GO:0072593//reactive oxygen species metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007596//blood coagulation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0002576//platelet degranulation;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0051781//positive regulation of cell division;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001892//embryonic placenta development",GO:0005518//collagen binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0042056//chemoattractant activity;GO:0005515//protein binding;GO:0008083//growth factor activity;GO:0016176//superoxide-generating NADPH oxidase activator activity;GO:0005161//platelet-derived growth factor receptor binding;GO:0042802//identical protein binding;GO:0048407//platelet-derived growth factor binding,K04359//HTLV-I infection;Gap junction;Pathways in cancer;Transcriptional misregulation in cancer;Prostate cancer;Cytokine-cytokine receptor interaction;Regulation of actin cytoskeleton;Melanoma;MAPK signaling pathway;Focal adhesion;Renal cell carcinoma;Glioma
51550,0,0,0,18,52,8,0,0,10,0,0,0,CINP;cyclin-dependent kinase 2 interacting protein,GO:0005634//nucleus,GO:0051301//cell division;GO:0007049//cell cycle;GO:0006260//DNA replication;GO:0006281//DNA repair,GO:0005515//protein binding,-
51552,74,0,1,91,181,10,40,0,13,0,13,0,"RAB14;RAB14, member RAS oncogene family",GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0005795//Golgi stack;GO:0005791//rough endoplasmic reticulum;GO:0005622//intracellular;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network;GO:0055037//recycling endosome;GO:0048471//perinuclear region of cytoplasm;GO:0030659//cytoplasmic vesicle membrane;GO:0005770//late endosome;GO:0045335//phagocytic vesicle;GO:0030670//phagocytic vesicle membrane;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0072372//primary cilium;GO:0005764//lysosome;GO:0000139//Golgi membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane,GO:0006184//GTP catabolic process;GO:0015031//protein transport;GO:0006895//Golgi to endosome transport;GO:0061024//membrane organization;GO:0032456//endocytic recycling;GO:0009790//embryo development;GO:0032880//regulation of protein localization;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0046907//intracellular transport;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0005515//protein binding,-
51554,0,0,0,0,0,0,0,0,16,0,0,0,ACKR4;atypical chemokine receptor 4,GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005887//integral component of plasma membrane;GO:0055037//recycling endosome,GO:0007186//G-protein coupled receptor signaling pathway;GO:0070098//chemokine-mediated signaling pathway;GO:0006955//immune response;GO:0006898//receptor-mediated endocytosis;GO:0006935//chemotaxis,GO:0004950//chemokine receptor activity;GO:0005515//protein binding;GO:0005044//scavenger receptor activity;GO:0019956//chemokine binding,-
51555,0,0,0,0,0,14,53,99,37,0,3,0,PEX5L;peroxisomal biogenesis factor 5-like,GO:0043235//receptor complex;GO:0005778//peroxisomal membrane;GO:0030425//dendrite;GO:0005829//cytosol,"GO:0016558//protein import into peroxisome matrix;GO:0045185//maintenance of protein location;GO:0016560//protein import into peroxisome matrix, docking;GO:0042391//regulation of membrane potential;GO:0043949//regulation of cAMP-mediated signaling",GO:0031267//small GTPase binding;GO:0000268//peroxisome targeting sequence binding;GO:0005052//peroxisome matrix targeting signal-1 binding,K13342//Peroxisome
51557,38,0,0,0,0,0,17,0,42,0,0,0,"LGSN;lengsin, lens protein with glutamine synthetase domain",GO:0005886//plasma membrane,GO:0006542//glutamine biosynthetic process,GO:0004356//glutamate-ammonia ligase activity,K11447//Transcriptional misregulation in cancer
51559,0,0,0,21,15,27,0,0,46,0,0,0,NT5DC3;5'-nucleotidase domain containing 3,GO:0043235//receptor complex;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K01081//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Nicotinate and nicotinamide metabolism;Metabolic pathways
5156,0,0,0,0,0,21,0,0,82,0,2,0,"PDGFRA;platelet-derived growth factor receptor, alpha polypeptide",GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0031226//intrinsic component of plasma membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane,GO:0046777//protein autophosphorylation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045740//positive regulation of DNA replication;GO:0030324//lung development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0055003//cardiac myofibril assembly;GO:0033327//Leydig cell differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0060325//face morphogenesis;GO:0023019//signal transduction involved in regulation of gene expression;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0030325//adrenal gland development;GO:0050920//regulation of chemotaxis;GO:0042060//wound healing;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0010863//positive regulation of phospholipase C activity;GO:0016032//viral process;GO:0072277//metanephric glomerular capillary formation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0001553//luteinization;GO:0048704//embryonic skeletal system morphogenesis;GO:0061298//retina vasculature development in camera-type eye;GO:0008210//estrogen metabolic process;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0060326//cell chemotaxis;GO:0030539//male genitalia development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0035790//platelet-derived growth factor receptor-alpha signaling pathway;GO:0045087//innate immune response;GO:0010544//negative regulation of platelet activation;GO:2000739//regulation of mesenchymal stem cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048015//phosphatidylinositol-mediated signaling;GO:0070527//platelet aggregation;GO:0048146//positive regulation of fibroblast proliferation;GO:0060021//palate development;GO:0001775//cell activation;GO:0048008//platelet-derived growth factor receptor signaling pathway,GO:0038085//vascular endothelial growth factor binding;GO:0005524//ATP binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0048407//platelet-derived growth factor binding;GO:0005018//platelet-derived growth factor alpha-receptor activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K04363//Pathways in cancer;Gap junction;HTLV-I infection;Endocytosis;Prostate cancer;Calcium signaling pathway;MAPK signaling pathway;Regulation of actin cytoskeleton;Melanoma;Cytokine-cytokine receptor interaction;Glioma;Focal adhesion
51560,89,0,0,0,9,9,0,0,6,115,4,0,"RAB6B;RAB6B, member RAS oncogene family",GO:0005794//Golgi apparatus;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0000139//Golgi membrane,"GO:0015031//protein transport;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,-
51561,0,0,43,0,16,0,0,6,0,0,14,0,"IL23A;interleukin 23, alpha subunit p19",GO:0070743//interleukin-23 complex,GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0042520//positive regulation of tyrosine phosphorylation of Stat4 protein;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0032735//positive regulation of interleukin-12 production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0050729//positive regulation of inflammatory response;GO:0042510//regulation of tyrosine phosphorylation of Stat1 protein;GO:0002230//positive regulation of defense response to virus by host;GO:0042098//T cell proliferation;GO:0045087//innate immune response;GO:0010535//positive regulation of activation of JAK2 kinase activity;GO:0032693//negative regulation of interleukin-10 production;GO:0050829//defense response to Gram-negative bacterium;GO:0032819//positive regulation of natural killer cell proliferation;GO:0051135//positive regulation of NK T cell activation;GO:0032740//positive regulation of interleukin-17 production;GO:0006954//inflammatory response;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048771//tissue remodeling;GO:0051142//positive regulation of NK T cell proliferation;GO:0051607//defense response to virus;GO:0043382//positive regulation of memory T cell differentiation;GO:0042104//positive regulation of activated T cell proliferation;GO:0032816//positive regulation of natural killer cell activation;GO:0032725//positive regulation of granulocyte macrophage colony-stimulating factor production;GO:0032729//positive regulation of interferon-gamma production;GO:0032760//positive regulation of tumor necrosis factor production;GO:2000330//positive regulation of T-helper 17 cell lineage commitment;GO:0045672//positive regulation of osteoclast differentiation;GO:0034105//positive regulation of tissue remodeling;GO:0032733//positive regulation of interleukin-10 production;GO:0042523//positive regulation of tyrosine phosphorylation of Stat5 protein;GO:0042346//positive regulation of NF-kappaB import into nucleus,GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0045519//interleukin-23 receptor binding,K05426//Tuberculosis;Pertussis;Rheumatoid arthritis;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
51562,0,37,1,0,9,0,0,0,16,0,0,0,MBIP;MAP3K12 binding inhibitory protein 1,GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0000173//inactivation of MAPK activity involved in osmosensory signaling pathway,GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity;GO:0042802//identical protein binding,K03635//Metabolic pathways;Folate biosynthesis;Sulfur relay system;K00962//Pyrimidine metabolism;Purine metabolism;Propanoate metabolism;RNA degradation
51564,166,1,0,16,27,17,0,8,72,0,2,306,HDAC7;histone deacetylase 7,GO:0000118//histone deacetylase complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0070933//histone H4 deacetylation;GO:0045668//negative regulation of osteoblast differentiation;GO:0007043//cell-cell junction assembly;GO:0007219//Notch signaling pathway;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0001570//vasculogenesis;GO:0070932//histone H3 deacetylation;GO:0032703//negative regulation of interleukin-2 production",GO:0070491//repressing transcription factor binding;GO:0005080//protein kinase C binding;GO:0033613//activating transcription factor binding;GO:0019901//protein kinase binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0071889//14-3-3 protein binding,K11408//Alcoholism
51566,0,56,0,107,94,0,18,0,7,0,0,0,"ARMCX3;armadillo repeat containing, X-linked 3",GO:0031307//integral component of mitochondrial outer membrane,GO:0034613//cellular protein localization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,-,-
51567,0,37,2,84,227,0,23,97,0,158,12,0,TDP2;tyrosyl-DNA phosphodiesterase 2,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0016605//PML body;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:2001141//regulation of RNA biosynthetic process;GO:0006302//double-strand break repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007166//cell surface receptor signaling pathway,GO:0004518//nuclease activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0070260//5'-tyrosyl-DNA phosphodiesterase activity;GO:0003714//transcription corepressor activity;GO:0036317//tyrosyl-RNA phosphodiesterase activity;GO:0030145//manganese ion binding;GO:0003697//single-stranded DNA binding,-
51569,0,122,2,195,411,9,0,0,44,108,0,0,UFM1;ubiquitin-fold modifier 1,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0071569//protein ufmylation;GO:0034976//response to endoplasmic reticulum stress,-,-
5157,0,0,0,0,0,15,0,0,0,0,10,0,PDGFRL;platelet-derived growth factor receptor-like,GO:0005576//extracellular region,GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004992//platelet activating factor receptor activity;GO:0005019//platelet-derived growth factor beta-receptor activity,K05098//Cytokine-cytokine receptor interaction;Endocytosis;Focal adhesion;VEGF signaling pathway;K05096//Transcriptional misregulation in cancer;Focal adhesion;Rheumatoid arthritis;Endocytosis;Cytokine-cytokine receptor interaction
51571,0,0,0,0,0,0,0,0,38,0,0,0,"FAM49B;family with sequence similarity 49, member B",GO:0005929//cilium;GO:0070062//extracellular vesicular exosome,-,-,-
51573,0,90,0,99,225,0,3,0,40,0,10,0,GDE1;glycerophosphodiester phosphodiesterase 1,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process,GO:0046872//metal ion binding;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0047395//glycerophosphoinositol glycerophosphodiesterase activity,K01126//Sphingolipid metabolism;Glycerophospholipid metabolism;Other glycan degradation
51574,0,0,0,5,84,0,0,0,32,0,0,0,"LARP7;La ribonucleoprotein domain family, member 7",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,GO:0006396//RNA processing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
51575,0,0,0,0,0,0,0,0,4,0,0,0,"ESF1;ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)",GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding,-
5158,5,13,0,0,0,0,0,27,40,113,11,392,"PDE6B;phosphodiesterase 6B, cGMP-specific, rod, beta",GO:0097381//photoreceptor disc membrane;GO:0005886//plasma membrane,"GO:0007603//phototransduction, visible light;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0060041//retina development in camera-type eye;GO:0046037//GMP metabolic process;GO:0007601//visual perception;GO:0051480//cytosolic calcium ion homeostasis","GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity;GO:0046872//metal ion binding",K13756//Phototransduction;Purine metabolism
51582,0,25,0,24,39,0,0,0,0,0,0,0,AZIN1;antizyme inhibitor 1,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006521//regulation of cellular amino acid metabolic process;GO:0006596//polyamine biosynthetic process;GO:0043086//negative regulation of catalytic activity;GO:0043085//positive regulation of catalytic activity;GO:0034641//cellular nitrogen compound metabolic process;GO:0042177//negative regulation of protein catabolic process;GO:0044281//small molecule metabolic process,GO:0042978//ornithine decarboxylase activator activity;GO:0003824//catalytic activity;GO:0004857//enzyme inhibitor activity,K01581//Lysine biosynthesis;Microbial metabolism in diverse environments;Metabolic pathways;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Glutathione metabolism
51585,0,0,0,25,32,43,13,0,25,33,0,0,PCF11;PCF11 cleavage and polyadenylation factor subunit,GO:0005849//mRNA cleavage factor complex;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0031124//mRNA 3'-end processing;GO:0006379//mRNA cleavage;GO:0006369//termination of RNA polymerase II transcription",-,K14400//mRNA surveillance pathway
51586,0,0,0,5,0,48,55,0,93,0,18,0,MED15;mediator complex subunit 15,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016592//mediator complex;GO:0005654//nucleoplasm;GO:0016020//membrane,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression,GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,-
51588,0,1,0,5,4,5,0,1,13,0,8,236,"PIAS4;protein inhibitor of activated STAT, 4",GO:0005730//nucleolus;GO:0016605//PML body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix,"GO:0033235//positive regulation of protein sumoylation;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:0016055//Wnt signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0019789//SUMO ligase activity,K16065//NF-kappa B signaling pathway;Jak-STAT signaling pathway;Ubiquitin mediated proteolysis
5159,52,0,0,0,0,0,10,0,23,7,9,0,"PDGFRB;platelet-derived growth factor receptor, beta polypeptide",GO:0043202//lysosomal lumen;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0031226//intrinsic component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005634//nucleus;GO:0005925//focal adhesion,GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0072278//metanephric comma-shaped body morphogenesis;GO:0046488//phosphatidylinositol metabolic process;GO:0060981//cell migration involved in coronary angiogenesis;GO:0035793//positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway;GO:0061298//retina vasculature development in camera-type eye;GO:0045840//positive regulation of mitosis;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0048839//inner ear development;GO:0032355//response to estradiol;GO:0010863//positive regulation of phospholipase C activity;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0071670//smooth muscle cell chemotaxis;GO:0016477//cell migration;GO:0035909//aorta morphogenesis;GO:0072277//metanephric glomerular capillary formation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042542//response to hydrogen peroxide;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0050921//positive regulation of chemotaxis;GO:0072262//metanephric glomerular mesangial cell proliferation involved in metanephros development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0032967//positive regulation of collagen biosynthetic process;GO:0014911//positive regulation of smooth muscle cell migration;GO:0006024//glycosaminoglycan biosynthetic process;GO:0009636//response to toxic substance;GO:0060326//cell chemotaxis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045087//innate immune response;GO:0001894//tissue homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0036120//cellular response to platelet-derived growth factor stimulus;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0072284//metanephric S-shaped body morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090280//positive regulation of calcium ion import;GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0048705//skeletal system morphogenesis;GO:0032526//response to retinoic acid;GO:2000573//positive regulation of DNA biosynthetic process;GO:0032956//regulation of actin cytoskeleton organization;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030335//positive regulation of cell migration;GO:0030325//adrenal gland development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0034405//response to fluid shear stress;GO:0048745//smooth muscle tissue development;GO:0042060//wound healing;GO:0035441//cell migration involved in vasculogenesis;GO:0055093//response to hyperoxia;GO:0055003//cardiac myofibril assembly;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0043406//positive regulation of MAP kinase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0072075//metanephric mesenchyme development;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0004992//platelet activating factor receptor activity;GO:0005515//protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005019//platelet-derived growth factor beta-receptor activity;GO:0005102//receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0019901//protein kinase binding;GO:0048407//platelet-derived growth factor binding;GO:0005161//platelet-derived growth factor receptor binding;GO:0038085//vascular endothelial growth factor binding;GO:0005524//ATP binding,K05089//Calcium signaling pathway;Prostate cancer;Gap junction;Pathways in cancer;HTLV-I infection;Glioma;Focal adhesion;MAPK signaling pathway;Cytokine-cytokine receptor interaction;Melanoma;Regulation of actin cytoskeleton
51592,0,40,0,51,232,13,0,0,60,79,0,1,TRIM33;tripartite motif containing 33,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,"GO:0030514//negative regulation of BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0010467//gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated",GO:0070412//R-SMAD binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0070410//co-SMAD binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,-
51593,84,50,1,28,48,16,0,0,16,0,25,0,"SRRT;serrate, RNA effector molecule",GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0031053//primary miRNA processing;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0046685//response to arsenic-containing substance;GO:0006355//regulation of transcription, DNA-templated;GO:0097150//neuronal stem cell maintenance",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
51594,95,1,1,13,7,81,11,0,36,0,6,273,NBAS;neuroblastoma amplified sequence,GO:0005737//cytoplasm;GO:0016020//membrane,"GO:0000956//nuclear-transcribed mRNA catabolic process;GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",-,K05869//Amphetamine addiction;Osteoclast differentiation;Neurotrophin signaling pathway;Cholinergic synapse;Alcoholism;Calcium signaling pathway;Long-term potentiation
51596,0,1,0,0,8,0,0,0,0,0,0,0,CUTA;cutA divalent cation tolerance homolog (E. coli),GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0008104//protein localization;GO:0010038//response to metal ion,GO:0019899//enzyme binding;GO:0005515//protein binding,-
51599,22,39,0,1,0,0,19,27,2,29,27,2,LSR;lipolysis stimulated lipoprotein receptor,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0034362//low-density lipoprotein particle;GO:0016021//integral component of membrane;GO:0034361//very-low-density lipoprotein particle;GO:0042627//chylomicron,GO:0001889//liver development;GO:0009790//embryo development,-,-
516,0,1,0,0,8,0,0,0,0,0,0,0,"ATP5G1;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0005743//mitochondrial inner membrane",GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0044237//cellular metabolic process,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0008289//lipid binding;GO:0005215//transporter activity,K02128//Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
5160,0,1,0,11,37,0,0,68,39,0,0,0,PDHA1;pyruvate dehydrogenase (lipoamide) alpha 1,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0045254//pyruvate dehydrogenase complex,GO:0006099//tricarboxylic acid cycle;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006090//pyruvate metabolic process,GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity,"K00161//Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Butanoate metabolism;Pyruvate metabolism;Valine, leucine and isoleucine biosynthesis;Citrate cycle (TCA cycle);Metabolic pathways"
51601,0,0,0,0,0,11,13,0,38,0,0,0,LIPT1;lipoyltransferase 1,GO:0005739//mitochondrion,GO:0006629//lipid metabolic process;GO:0006464//cellular protein modification process;GO:0009249//protein lipoylation,"GO:0016746//transferase activity, transferring acyl groups",K10105//Metabolic pathways;Lipoic acid metabolism
51602,0,0,0,10,42,15,27,0,33,0,0,0,NOP58;NOP58 ribonucleoprotein,GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0005634//nucleus;GO:0016020//membrane;GO:0070761//pre-snoRNP complex;GO:0005737//cytoplasm;GO:0031428//box C/D snoRNP complex,GO:0006608//snRNP protein import into nucleus;GO:0016049//cell growth;GO:0006364//rRNA processing,GO:0030515//snoRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14565//Ribosome biogenesis in eukaryotes
51603,0,0,0,10,15,0,23,0,12,0,1,0,METTL13;methyltransferase like 13,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
51604,0,0,0,0,0,1,65,0,20,0,10,0,"PIGT;phosphatidylinositol glycan anchor biosynthesis, class T",GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0042765//GPI-anchor transamidase complex;GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0051402//neuron apoptotic process;GO:0016255//attachment of GPI anchor to protein;GO:0030182//neuron differentiation;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation,GO:0005515//protein binding;GO:0003923//GPI-anchor transamidase activity,K05292//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
51605,0,0,0,32,0,0,25,0,24,0,0,0,TRMT6;tRNA methyltransferase 6 homolog (S. cerevisiae),GO:0005634//nucleus,GO:0006413//translational initiation;GO:0006446//regulation of translational initiation;GO:0008033//tRNA processing,GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding,-
51606,0,32,0,0,2,0,1,0,32,55,0,0,"ATP6V1H;ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H","GO:0000221//vacuolar proton-transporting V-type ATPase, V1 domain;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005765//lysosomal membrane",GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0016032//viral process;GO:0050790//regulation of catalytic activity;GO:0006200//ATP catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006897//endocytosis;GO:0007035//vacuolar acidification;GO:0050690//regulation of defense response to virus by virus;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport,"GO:0030234//enzyme regulator activity;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism",K02144//Rheumatoid arthritis;Phagosome;Tuberculosis;Synaptic vesicle cycle;Oxidative phosphorylation;Metabolic pathways;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Lysosome
51608,0,0,0,2,2,0,12,38,32,0,7,0,GET4;golgi to ER traffic protein 4 homolog (S. cerevisiae),GO:0071818//BAT3 complex;GO:0005829//cytosol,GO:0006810//transport;GO:0071816//tail-anchored membrane protein insertion into ER membrane,-,-
5161,0,0,0,0,0,14,0,0,8,0,0,0,PDHA2;pyruvate dehydrogenase (lipoamide) alpha 2,GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0006099//tricarboxylic acid cycle;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0006090//pyruvate metabolic process,GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity,"K00161//Microbial metabolism in diverse environments;Butanoate metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Pyruvate metabolism;Valine, leucine and isoleucine biosynthesis;Metabolic pathways;Citrate cycle (TCA cycle)"
51611,0,52,0,15,10,0,0,0,0,0,31,0,DPH5;diphthamide biosynthesis 5,-,GO:0032259//methylation;GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine,GO:0004164//diphthine synthase activity,-
51614,0,0,1,19,31,0,0,29,10,0,10,0,ERGIC3;ERGIC and golgi 3,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0016192//vesicle-mediated transport,-,-
51616,0,0,0,42,103,25,0,0,1,0,29,0,"TAF9B;TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa",GO:0033276//transcription factor TFTC complex;GO:0005669//transcription factor TFIID complex,"GO:0014070//response to organic cyclic compound;GO:0006352//DNA-templated transcription, initiation;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0030307//positive regulation of cell growth;GO:0012501//programmed cell death;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization",GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K03133//Basal transcription factors;Herpes simplex infection
51617,0,0,0,0,0,0,0,26,14,0,0,300,HMP19;HMP19 protein,GO:0032585//multivesicular body membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0048268//clathrin coat assembly;GO:0007212//dopamine receptor signaling pathway,GO:0032051//clathrin light chain binding,K15493//Dopaminergic synapse
51619,0,0,0,20,42,0,42,217,81,0,115,1,UBE2D4;ubiquitin-conjugating enzyme E2D 4 (putative),-,GO:0070936//protein K48-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0085020//protein K6-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0035519//protein K29-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K06689//Shigellosis;Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum
5162,55,0,1,29,30,0,0,0,34,0,7,0,PDHB;pyruvate dehydrogenase (lipoamide) beta,GO:0070062//extracellular vesicular exosome;GO:0045254//pyruvate dehydrogenase complex;GO:0005634//nucleus;GO:0005759//mitochondrial matrix,GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0006086//acetyl-CoA biosynthetic process from pyruvate;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006006//glucose metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006090//pyruvate metabolic process,GO:0005515//protein binding;GO:0004739//pyruvate dehydrogenase (acetyl-transferring) activity,"K00162//Pyruvate metabolism;Citrate cycle (TCA cycle);Valine, leucine and isoleucine biosynthesis;Metabolic pathways;Purine metabolism;Butanoate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis"
51621,36,34,0,0,5,24,0,98,25,0,0,0,KLF13;Kruppel-like factor 13,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation;GO:0045647//negative regulation of erythrocyte differentiation,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
51622,0,0,0,0,1,0,24,0,0,0,0,0,CCZ1;CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae),GO:0005765//lysosomal membrane,-,-,K08269//Regulation of autophagy;mTOR signaling pathway
51626,0,2,0,9,30,42,5,0,37,0,0,0,"DYNC2LI1;dynein, cytoplasmic 2, light intermediate chain 1",GO:0072372//primary cilium;GO:0005829//cytosol;GO:0005858//axonemal dynein complex;GO:0030990//intraciliary transport particle;GO:0005930//axoneme;GO:0005881//cytoplasmic microtubule;GO:0036064//ciliary basal body;GO:0031512//motile primary cilium;GO:0045177//apical part of cell,GO:0007368//determination of left/right symmetry;GO:0042384//cilium assembly;GO:0008152//metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0003774//motor activity;GO:0005515//protein binding,K10417//Vasopressin-regulated water reabsorption
51629,0,0,2,0,2,0,0,0,8,0,0,345,"SLC25A39;solute carrier family 25, member 39",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006810//transport;GO:0006783//heme biosynthetic process,-,-
5163,0,15,0,7,31,15,0,40,24,0,8,0,"PDK1;pyruvate dehydrogenase kinase, isozyme 1",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0008283//cell proliferation;GO:0006468//protein phosphorylation;GO:0010906//regulation of glucose metabolic process;GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0006006//glucose metabolic process,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K12077//Fc epsilon RI signaling pathway;Hepatitis C;Neurotrophin signaling pathway;Toxoplasmosis;T cell receptor signaling pathway
51631,0,0,167,14,16,0,19,379,12,0,67,1,LUC7L2;LUC7-like 2 (S. cerevisiae),GO:0016607//nuclear speck;GO:0005685//U1 snRNP,GO:0006376//mRNA splice site selection,GO:0019899//enzyme binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding,-
51633,0,0,0,0,0,0,47,0,68,17,0,0,OTUD6B;OTU domain containing 6B,-,GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity,K12655//RIG-I-like receptor signaling pathway;K13349//Peroxisome
51634,0,0,0,0,0,0,0,0,31,0,0,0,"RBMX2;RNA binding motif protein, X-linked 2",-,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
51635,0,1,0,36,41,1,0,0,16,0,0,0,DHRS7;dehydrogenase/reductase (SDR family) member 7,GO:0016020//membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
51637,0,0,0,13,66,0,0,0,0,0,2,0,C14orf166;chromosome 14 open reading frame 166,GO:0072669//tRNA-splicing ligase complex;GO:0005815//microtubule organizing center;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005730//nucleolus,"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0050658//RNA transport;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0016032//viral process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0003723//RNA binding;GO:0000993//RNA polymerase II core binding,-
51639,0,0,0,38,118,0,0,0,12,0,0,0,"SF3B6;splicing factor 3b, subunit 6, 14kDa",GO:0005689//U12-type spliceosomal complex;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K12833//Spliceosome
5164,0,0,0,14,0,11,0,2,30,0,0,0,"PDK2;pyruvate dehydrogenase kinase, isozyme 2",GO:0005759//mitochondrial matrix;GO:0005967//mitochondrial pyruvate dehydrogenase complex,GO:0044281//small molecule metabolic process;GO:0006111//regulation of gluconeogenesis;GO:0034614//cellular response to reactive oxygen species;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0006885//regulation of pH;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0006006//glucose metabolic process;GO:0031670//cellular response to nutrient;GO:0042593//glucose homeostasis;GO:0006468//protein phosphorylation;GO:0010906//regulation of glucose metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate,GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding,-
51642,0,26,0,6,30,0,1,0,0,0,0,0,MRPL48;mitochondrial ribosomal protein L48,GO:0005761//mitochondrial ribosome,-,GO:0005515//protein binding,-
51643,0,0,0,11,13,0,0,0,15,0,0,0,TMBIM4;transmembrane BAX inhibitor motif containing 4,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005795//Golgi stack,GO:0006915//apoptotic process;GO:0050848//regulation of calcium-mediated signaling;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding,-
51645,0,1,0,9,53,0,0,0,63,0,14,0,PPIL1;peptidylprolyl isomerase (cyclophilin)-like 1,GO:0071013//catalytic step 2 spliceosome;GO:0070062//extracellular vesicular exosome,"GO:0000398//mRNA splicing, via spliceosome;GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization",GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding,K12733//Spliceosome
51646,0,68,1,34,53,0,0,0,3,0,17,0,YPEL5;yippee-like 5 (Drosophila),-,-,-,-
51647,0,0,0,0,25,0,0,0,5,0,0,0,"FAM96B;family with sequence similarity 96, member B",GO:0005730//nucleolus;GO:0097361//CIA complex;GO:0071817//MMXD complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle,GO:0007059//chromosome segregation;GO:0044281//small molecule metabolic process,GO:0005515//protein binding,-
51649,0,3,0,40,182,0,0,122,17,0,0,0,MRPS23;mitochondrial ribosomal protein S23,GO:0045111//intermediate filament cytoskeleton;GO:0005739//mitochondrion;GO:0005840//ribosome;GO:0031965//nuclear membrane,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
5165,0,67,0,34,87,0,46,4,64,0,4,0,"PDK3;pyruvate dehydrogenase kinase, isozyme 3",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0097411//hypoxia-inducible factor-1alpha signaling pathway;GO:0008219//cell death;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0006090//pyruvate metabolic process;GO:0006006//glucose metabolic process;GO:0044237//cellular metabolic process;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0044281//small molecule metabolic process;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0071333//cellular response to glucose stimulus;GO:0010906//regulation of glucose metabolic process;GO:0071398//cellular response to fatty acid,GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
51650,0,1,0,0,33,0,0,0,5,0,0,0,MRPS33;mitochondrial ribosomal protein S33,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K09635//Influenza A
51652,0,0,0,0,11,2,0,0,0,0,0,0,CHMP3;charged multivesicular body protein 3,GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0019058//viral life cycle;GO:0050792//regulation of viral process;GO:0007049//cell cycle;GO:0016032//viral process;GO:0051301//cell division;GO:1902188//positive regulation of viral release from host cell;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0006915//apoptotic process,GO:0005515//protein binding,K12193//Endocytosis
51654,0,0,0,7,11,0,0,0,10,0,1,0,CDK5RAP1;CDK5 regulatory subunit associated protein 1,GO:0005737//cytoplasm,GO:0006400//tRNA modification;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045664//regulation of neuron differentiation;GO:0007420//brain development,"GO:0019901//protein kinase binding;GO:0046872//metal ion binding;GO:0016740//transferase activity;GO:0032403//protein complex binding;GO:0051539//4 iron, 4 sulfur cluster binding",-
51655,0,25,3,1,20,0,26,0,5,0,0,0,"RASD1;RAS, dexamethasone-induced 1",GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0007263//nitric oxide mediated signal transduction;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway",GO:0003924//GTPase activity;GO:0005525//GTP binding,-
51657,0,31,0,4,12,12,0,0,18,0,0,0,STYXL1;serine/threonine/tyrosine interacting-like 1,-,GO:0035556//intracellular signal transduction;GO:0006470//protein dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
51659,0,0,0,0,1,0,0,0,0,0,14,0,GINS2;GINS complex subunit 2 (Psf2 homolog),GO:0005654//nucleoplasm,GO:0000278//mitotic cell cycle;GO:0006271//DNA strand elongation involved in DNA replication,GO:0005515//protein binding,-
5166,2,0,0,0,68,12,0,0,32,0,0,0,"PDK4;pyruvate dehydrogenase kinase, isozyme 4",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0006006//glucose metabolic process;GO:0044237//cellular metabolic process;GO:0045124//regulation of bone resorption;GO:0009267//cellular response to starvation;GO:0008286//insulin receptor signaling pathway;GO:0071398//cellular response to fatty acid;GO:0010906//regulation of glucose metabolic process;GO:0006468//protein phosphorylation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0006090//pyruvate metabolic process;GO:0006885//regulation of pH;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0042593//glucose homeostasis;GO:0042304//regulation of fatty acid biosynthetic process;GO:0046320//regulation of fatty acid oxidation;GO:0042594//response to starvation;GO:2000811//negative regulation of anoikis,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004740//pyruvate dehydrogenase (acetyl-transferring) kinase activity;GO:0004672//protein kinase activity,-
51660,0,0,0,1,19,29,0,0,14,0,0,0,MPC1;mitochondrial pyruvate carrier 1,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006850//mitochondrial pyruvate transport;GO:0006090//pyruvate metabolic process;GO:1901475//pyruvate transmembrane transport,GO:0050833//pyruvate transmembrane transporter activity,-
51661,0,0,0,0,5,8,0,0,33,0,0,126,FKBP7;FK506 binding protein 7,GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0061077//chaperone-mediated protein folding;GO:0000413//protein peptidyl-prolyl isomerization,GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding,-
51663,0,0,0,16,81,0,68,22,38,10,14,0,ZFR;zinc finger RNA binding protein,GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
51665,36,0,0,1,17,5,13,141,37,0,24,0,ASB1;ankyrin repeat and SOCS box containing 1,GO:0005622//intracellular,GO:0042036//negative regulation of cytokine biosynthetic process;GO:0030539//male genitalia development;GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
51666,0,0,0,0,0,15,15,0,38,0,0,0,ASB4;ankyrin repeat and SOCS box containing 4,GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031466//Cul5-RING ubiquitin ligase complex,GO:0051865//protein autoubiquitination;GO:0035556//intracellular signal transduction;GO:2001214//positive regulation of vasculogenesis,GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity,-
51667,0,2,0,0,35,52,44,0,27,0,0,0,NUB1;negative regulator of ubiquitin-like proteins 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0034612//response to tumor necrosis factor;GO:0016567//protein ubiquitination;GO:0034341//response to interferon-gamma;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding,-
51668,21,0,0,6,66,0,0,0,0,0,0,0,"HSPB11;heat shock protein family B (small), member 11",GO:0005929//cilium;GO:0070062//extracellular vesicular exosome;GO:0030992//intraciliary transport particle B;GO:0005813//centrosome,GO:0001501//skeletal system development;GO:0030324//lung development;GO:0015031//protein transport;GO:0042384//cilium assembly;GO:0070986//left/right axis specification;GO:0007155//cell adhesion;GO:0006950//response to stress;GO:0007224//smoothened signaling pathway;GO:0007507//heart development,GO:0046872//metal ion binding,-
51669,0,1,0,13,172,0,0,0,0,0,13,0,SARAF;store-operated calcium entry-associated regulatory factor,GO:0030176//integral component of endoplasmic reticulum membrane,GO:2001256//regulation of store-operated calcium entry;GO:0006816//calcium ion transport,GO:0005515//protein binding,-
5167,0,0,0,0,1,8,33,0,39,0,20,0,ENPP1;ectonucleotide pyrophosphatase/phosphodiesterase 1,GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane,GO:0030643//cellular phosphate ion homeostasis;GO:0030730//sequestering of triglyceride;GO:0045599//negative regulation of fat cell differentiation;GO:0030308//negative regulation of cell growth;GO:0006955//immune response;GO:0006091//generation of precursor metabolites and energy;GO:0032869//cellular response to insulin stimulus;GO:0044281//small molecule metabolic process;GO:0030500//regulation of bone mineralization;GO:0006767//water-soluble vitamin metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0009143//nucleoside triphosphate catabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0030279//negative regulation of ossification;GO:0006771//riboflavin metabolic process;GO:0046849//bone remodeling;GO:0031953//negative regulation of protein autophosphorylation;GO:0030505//inorganic diphosphate transport;GO:0006898//receptor-mediated endocytosis;GO:0006766//vitamin metabolic process;GO:0006200//ATP catabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0031214//biomineral tissue development;GO:0046325//negative regulation of glucose import;GO:0046627//negative regulation of insulin receptor signaling pathway,GO:0005515//protein binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0042803//protein homodimerization activity;GO:0035529//NADH pyrophosphatase activity;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0003676//nucleic acid binding;GO:0030247//polysaccharide binding;GO:0005044//scavenger receptor activity;GO:0004528//phosphodiesterase I activity;GO:0005158//insulin receptor binding;GO:0004551//nucleotide diphosphatase activity;GO:0005524//ATP binding,K01513//Metabolic pathways;Nicotinate and nicotinamide metabolism;Riboflavin metabolism;Purine metabolism;Starch and sucrose metabolism;Pantothenate and CoA biosynthesis
51673,0,0,0,0,0,21,0,45,0,1,0,0,TPPP3;tubulin polymerization-promoting protein family member 3,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0001578//microtubule bundle formation,GO:0015631//tubulin binding,-
51676,0,0,0,0,0,0,11,0,15,0,0,0,ASB2;ankyrin repeat and SOCS box containing 2,GO:0031466//Cul5-RING ubiquitin ligase complex,GO:0035556//intracellular signal transduction;GO:0007165//signal transduction;GO:0045445//myoblast differentiation;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0035914//skeletal muscle cell differentiation,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
51678,1,0,27,3,95,35,41,0,21,1,0,316,"MPP6;membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006461//protein complex assembly,GO:0005515//protein binding;GO:0030165//PDZ domain binding,K06103//Tight junction
5168,14,0,0,0,14,0,0,0,72,0,1,0,ENPP2;ectonucleotide pyrophosphatase/phosphodiesterase 2,GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,GO:0034638//phosphatidylcholine catabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0030334//regulation of cell migration;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0009395//phospholipid catabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006928//cellular component movement;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006898//receptor-mediated endocytosis,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0008134//transcription factor binding;GO:0030247//polysaccharide binding;GO:0003676//nucleic acid binding;GO:0016787//hydrolase activity;GO:0005044//scavenger receptor activity;GO:0047391//alkylglycerophosphoethanolamine phosphodiesterase activity;GO:0004551//nucleotide diphosphatase activity;GO:0004528//phosphodiesterase I activity;GO:0004622//lysophospholipase activity,K01122//Ether lipid metabolism
51684,0,0,0,0,14,0,0,56,52,53,2,1,SUFU;suppressor of fused homolog (Drosophila),GO:0072372//primary cilium;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007165//signal transduction;GO:0001843//neural tube closure;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0007275//multicellular organismal development;GO:0006508//proteolysis;GO:0021775//smoothened signaling pathway involved in ventral spinal cord interneuron specification;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0001501//skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0045879//negative regulation of smoothened signaling pathway;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043588//skin development;GO:0021776//smoothened signaling pathway involved in spinal cord motor neuron cell fate specification;GO:0001947//heart looping",GO:0004871//signal transducer activity;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity;GO:0008013//beta-catenin binding,K06229//Basal cell carcinoma;Hedgehog signaling pathway;Pathways in cancer
51686,0,492,337,427,635,0,2,247,38,0,529,227,OAZ3;ornithine decarboxylase antizyme 3,GO:0005829//cytosol;GO:0036126//sperm flagellum;GO:0072562//blood microparticle;GO:0005634//nucleus,GO:0044281//small molecule metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0007283//spermatogenesis;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0043086//negative regulation of catalytic activity;GO:0006521//regulation of cellular amino acid metabolic process,GO:0071532//ankyrin repeat binding;GO:0008073//ornithine decarboxylase inhibitor activity;GO:0005515//protein binding,-
5169,0,0,0,0,0,0,24,0,62,0,0,0,ENPP3;ectonucleotide pyrophosphatase/phosphodiesterase 3,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0009143//nucleoside triphosphate catabolic process;GO:0030505//inorganic diphosphate transport;GO:0006796//phosphate-containing compound metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0006955//immune response,GO:0035529//NADH pyrophosphatase activity;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0046872//metal ion binding;GO:0005044//scavenger receptor activity;GO:0030247//polysaccharide binding;GO:0003676//nucleic acid binding;GO:0004551//nucleotide diphosphatase activity;GO:0004528//phosphodiesterase I activity,K01513//Nicotinate and nicotinamide metabolism;Metabolic pathways;Starch and sucrose metabolism;Pantothenate and CoA biosynthesis;Purine metabolism;Riboflavin metabolism
51690,0,6,0,0,0,0,0,0,11,0,4,0,"LSM7;LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005829//cytosol;GO:0005681//spliceosomal complex,"GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006397//mRNA processing;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0017070//U6 snRNA binding;GO:0005515//protein binding,K12626//Spliceosome;RNA degradation
51691,197,104,1,26,79,25,32,0,25,0,26,0,"LSM8;LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005681//spliceosomal complex,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0017070//U6 snRNA binding,K12627//RNA degradation;Spliceosome
51692,0,0,1,7,89,0,0,0,72,0,13,0,"CPSF3;cleavage and polyadenylation specific factor 3, 73kDa",GO:0005654//nucleoplasm;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0030529//ribonucleoprotein complex,"GO:0031124//mRNA 3'-end processing;GO:0006398//histone mRNA 3'-end processing;GO:0006379//mRNA cleavage;GO:0006406//mRNA export from nucleus;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006378//mRNA polyadenylation;GO:0006369//termination of RNA polymerase II transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter",GO:0008409//5'-3' exonuclease activity;GO:0004521//endoribonuclease activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K14403//mRNA surveillance pathway
51693,0,0,0,0,15,0,4,0,0,0,0,0,TRAPPC2L;trafficking protein particle complex 2-like,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0006888//ER to Golgi vesicle-mediated transport,GO:0005515//protein binding,-
51696,56,0,28,40,11,0,0,0,49,0,4,0,HECA;headcase homolog (Drosophila),GO:0016020//membrane,GO:0030323//respiratory tube development,-,K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
51699,0,38,1,21,40,0,33,0,28,0,0,0,VPS29;vacuolar protein sorting 29 homolog (S. cerevisiae),GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0016311//dephosphorylation;GO:0015031//protein transport,GO:0004647//phosphoserine phosphatase activity;GO:0046872//metal ion binding,-
517,0,20,1,0,62,16,31,0,0,0,0,13,"ATP5G2;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016021//integral component of membrane;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o)",GO:0045471//response to ethanol;GO:0015991//ATP hydrolysis coupled proton transport;GO:0015986//ATP synthesis coupled proton transport,GO:0005215//transporter activity;GO:0008289//lipid binding;GO:0015078//hydrogen ion transmembrane transporter activity,K02128//Metabolic pathways;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation
5170,0,0,1,17,53,12,2,76,0,125,17,0,PDPK1;3-phosphoinositide dependent protein kinase 1,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0042995//cell projection,"GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043304//regulation of mast cell degranulation;GO:0007596//blood coagulation;GO:0003323//type B pancreatic cell development;GO:0008286//insulin receptor signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0016477//cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030168//platelet activation;GO:0032869//cellular response to insulin stimulus;GO:0006351//transcription, DNA-templated;GO:0048015//phosphatidylinositol-mediated signaling;GO:0035556//intracellular signal transduction;GO:0045087//innate immune response;GO:0010594//regulation of endothelial cell migration;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission;GO:0019722//calcium-mediated signaling;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0048041//focal adhesion assembly;GO:0046777//protein autophosphorylation;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0010518//positive regulation of phospholipase activity;GO:0006972//hyperosmotic response;GO:0030036//actin cytoskeleton organization;GO:0031295//T cell costimulation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0006355//regulation of transcription, DNA-templated;GO:0008543//fibroblast growth factor receptor signaling pathway",GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0016004//phospholipase activator activity;GO:0019901//protein kinase binding;GO:0004676//3-phosphoinositide-dependent protein kinase activity;GO:0043274//phospholipase binding;GO:0005524//ATP binding;GO:0005158//insulin receptor binding;GO:0016301//kinase activity,K06276//mTOR signaling pathway;Non-small cell lung cancer;Endometrial cancer;Focal adhesion;Insulin signaling pathway;PPAR signaling pathway;Prostate cancer;Aldosterone-regulated sodium reabsorption
51700,0,0,0,0,27,10,0,0,0,0,20,332,CYB5R2;cytochrome b5 reductase 2,GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005634//nucleus,GO:0016126//sterol biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H",K00326//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
51701,179,17,0,9,18,6,0,29,42,0,0,0,NLK;nemo-like kinase,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0018107//peptidyl-threonine phosphorylation;GO:0033136//serine phosphorylation of STAT3 protein;GO:0000165//MAPK cascade;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0046777//protein autophosphorylation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway",GO:0000287//magnesium ion binding;GO:0042169//SH2 domain binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0031625//ubiquitin protein ligase binding;GO:0004672//protein kinase activity;GO:0004707//MAP kinase activity,K04468//Adherens junction;Wnt signaling pathway;MAPK signaling pathway
51702,10,0,0,0,9,0,16,0,47,0,10,0,"PADI3;peptidyl arginine deiminase, type III",GO:0005737//cytoplasm,GO:0018101//protein citrullination,GO:0005509//calcium ion binding;GO:0004668//protein-arginine deiminase activity,-
51703,84,0,0,0,11,32,0,0,30,0,16,1,ACSL5;acyl-CoA synthetase long-chain family member 5,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane,GO:0001676//long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:2001236//regulation of extrinsic apoptotic signaling pathway,GO:0005524//ATP binding;GO:0004467//long-chain fatty acid-CoA ligase activity,K01897//Metabolic pathways;PPAR signaling pathway;Adipocytokine signaling pathway;Ribosome;Fatty acid metabolism;Peroxisome
51704,0,0,0,0,0,0,0,48,60,0,0,0,"GPRC5B;G protein-coupled receptor, class C, group 5, member B",GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0030659//cytoplasmic vesicle membrane;GO:0045121//membrane raft;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0045666//positive regulation of neuron differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0010976//positive regulation of neuron projection development;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0060907//positive regulation of macrophage cytokine production;GO:0007626//locomotory behavior;GO:0042593//glucose homeostasis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0050729//positive regulation of inflammatory response,GO:0030295//protein kinase activator activity;GO:0004930//G-protein coupled receptor activity;GO:0001664//G-protein coupled receptor binding;GO:0019901//protein kinase binding,-
51705,0,0,0,0,0,3,70,0,41,0,0,0,EMCN;endomucin,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
51706,0,0,0,0,0,0,16,92,3,0,18,281,CYB5R1;cytochrome b5 reductase 1,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0016126//sterol biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H",K00326//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
51710,0,35,0,0,17,0,0,0,19,0,0,0,ZNF44;zinc finger protein 44,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
51714,0,1,0,12,71,0,0,0,10,0,0,0,SELT;selenoprotein T,GO:0005783//endoplasmic reticulum,GO:0031016//pancreas development;GO:0001514//selenocysteine incorporation;GO:0045454//cell redox homeostasis;GO:0035773//insulin secretion involved in cellular response to glucose stimulus,GO:0008430//selenium binding,-
51715,0,82,124,68,149,0,2,0,59,310,12,0,"RAB23;RAB23, member RAS oncogene family",GO:0005737//cytoplasm;GO:0005776//autophagic vacuole;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0045335//phagocytic vesicle,GO:0021513//spinal cord dorsal/ventral patterning;GO:0008589//regulation of smoothened signaling pathway;GO:0042384//cilium assembly;GO:0015031//protein transport;GO:0006968//cellular defense response;GO:0042733//embryonic digit morphogenesis;GO:0006184//GTP catabolic process;GO:0000045//autophagic vacuole assembly;GO:0097094//craniofacial suture morphogenesis;GO:0045861//negative regulation of proteolysis;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0007264//small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K06234//Hedgehog signaling pathway
51716,0,0,0,0,0,0,2,0,26,0,0,0,CES1P1;carboxylesterase 1 pseudogene 1,-,-,-,K01044//Metabolic pathways;Drug metabolism - other enzymes
51719,0,54,1,44,235,17,0,0,8,0,8,1,CAB39;calcium binding protein 39,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex,GO:2000681//negative regulation of rubidium ion transport;GO:0071476//cellular hypotonic response;GO:0051291//protein heterooligomerization;GO:0035556//intracellular signal transduction;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0032147//activation of protein kinase activity;GO:0008286//insulin receptor signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:2000687//negative regulation of rubidium ion transmembrane transporter activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0018105//peptidyl-serine phosphorylation;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0023014//signal transduction by phosphorylation;GO:0007050//cell cycle arrest,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity,K08272//mTOR signaling pathway
5172,0,0,40,32,1,0,48,2,44,0,55,0,"SLC26A4;solute carrier family 26 (anion exchanger), member 4",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0015698//inorganic anion transport;GO:1902358//sulfate transmembrane transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0032880//regulation of protein localization;GO:0007605//sensory perception of sound;GO:0015705//iodide transport;GO:1902476//chloride transmembrane transport;GO:0006885//regulation of pH;GO:0008272//sulfate transport,GO:0015108//chloride transmembrane transporter activity;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015111//iodide transmembrane transporter activity,-
51720,0,19,0,17,111,19,0,89,33,0,19,0,UIMC1;ubiquitin interaction motif containing 1,GO:0005634//nucleus;GO:0070531//BRCA1-A complex,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045739//positive regulation of DNA repair;GO:0006302//double-strand break repair;GO:0010212//response to ionizing radiation;GO:0031572//G2 DNA damage checkpoint;GO:0070537//histone H2A K63-linked deubiquitination",GO:0046965//retinoid X receptor binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0070530//K63-linked polyubiquitin binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption
51725,148,0,0,0,0,0,18,0,61,0,0,0,FBXO40;F-box protein 40,GO:0005737//cytoplasm,GO:0042692//muscle cell differentiation;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity,-
51726,0,0,0,0,8,13,13,0,31,0,0,0,"DNAJB11;DnaJ (Hsp40) homolog, subfamily B, member 11",GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006457//protein folding;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0016556//mRNA modification,GO:0005515//protein binding;GO:0051082//unfolded protein binding,K09517//Protein processing in endoplasmic reticulum
51727,0,311,3,245,946,0,15,0,20,0,0,329,"CMPK1;cytidine monophosphate (UMP-CMP) kinase 1, cytosolic",GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006222//UMP biosynthetic process;GO:0009220//pyrimidine ribonucleotide biosynthetic process;GO:0006225//UDP biosynthetic process;GO:0006240//dCDP biosynthetic process;GO:0006227//dUDP biosynthetic process;GO:0006165//nucleoside diphosphate phosphorylation;GO:0009142//nucleoside triphosphate biosynthetic process;GO:0022602//ovulation cycle process;GO:0046705//CDP biosynthetic process;GO:0018963//phthalate metabolic process,GO:0033862//UMP kinase activity;GO:0004849//uridine kinase activity;GO:0004127//cytidylate kinase activity;GO:0004550//nucleoside diphosphate kinase activity;GO:0005524//ATP binding,K13800//Pyrimidine metabolism;Metabolic pathways
51728,0,0,2,4,10,0,0,0,0,0,0,0,"POLR3K;polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa",GO:0005829//cytosol;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm,GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0032481//positive regulation of type I interferon production;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0045087//innate immune response,GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003899//DNA-directed RNA polymerase activity,K03019//Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism;Cytosolic DNA-sensing pathway;Metabolic pathways
51729,0,43,0,31,78,3,70,139,15,0,9,0,WBP11;WW domain binding protein 11,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck,GO:0006364//rRNA processing;GO:0008380//RNA splicing;GO:0050790//regulation of catalytic activity;GO:0006397//mRNA processing,GO:0008599//protein phosphatase type 1 regulator activity;GO:0050699//WW domain binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K12866//Spliceosome
5173,0,0,0,0,0,0,0,3,28,0,10,0,PDYN;prodynorphin,GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0008219//cell death;GO:0007218//neuropeptide signaling pathway;GO:0007268//synaptic transmission,GO:0001515//opioid peptide activity,K15840//Cocaine addiction;Amphetamine addiction;Alcoholism
51733,0,0,0,1,2,0,11,1,27,0,3,0,"UPB1;ureidopropionase, beta",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0019483//beta-alanine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0046872//metal ion binding;GO:0003837//beta-ureidopropionase activity,K01431//beta-Alanine metabolism;Metabolic pathways;Drug metabolism - other enzymes;Pyrimidine metabolism;Pantothenate and CoA biosynthesis
51734,0,2,1,0,22,0,0,0,0,0,0,0,MSRB1;methionine sulfoxide reductase B1,GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process;GO:0045087//innate immune response;GO:0030041//actin filament polymerization;GO:0030091//protein repair,GO:0008270//zinc ion binding;GO:0033743//peptide-methionine (R)-S-oxide reductase activity;GO:0003779//actin binding;GO:0070191//methionine-R-sulfoxide reductase activity,-
51735,34,17,1,21,38,14,43,121,129,86,1,0,RAPGEF6;Rap guanine nucleotide exchange factor (GEF) 6,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0043547//positive regulation of GTPase activity;GO:0007265//Ras protein signal transduction;GO:0043087//regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0017016//Ras GTPase binding,-
51738,0,0,0,10,23,0,0,0,24,2,0,0,GHRL;ghrelin/obestatin prepropeptide,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0030424//axon;GO:0034774//secretory granule lumen;GO:0005788//endoplasmic reticulum lumen,"GO:0050728//negative regulation of inflammatory response;GO:0040013//negative regulation of locomotion;GO:0044267//cellular protein metabolic process;GO:0046697//decidualization;GO:0043627//response to estrogen;GO:0051461//positive regulation of corticotropin secretion;GO:0060399//positive regulation of growth hormone receptor signaling pathway;GO:0006006//glucose metabolic process;GO:0046010//positive regulation of circadian sleep/wake cycle, non-REM sleep;GO:0001937//negative regulation of endothelial cell proliferation;GO:0030252//growth hormone secretion;GO:0009725//response to hormone;GO:0051965//positive regulation of synapse assembly;GO:0032691//negative regulation of interleukin-1 beta production;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0000187//activation of MAPK activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001696//gastric acid secretion;GO:0008154//actin polymerization or depolymerization;GO:0046676//negative regulation of insulin secretion;GO:0040018//positive regulation of multicellular organism growth;GO:0042127//regulation of cell proliferation;GO:0032024//positive regulation of insulin secretion;GO:0016525//negative regulation of angiogenesis;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0009755//hormone-mediated signaling pathway;GO:0042322//negative regulation of circadian sleep/wake cycle, REM sleep;GO:0051464//positive regulation of cortisol secretion;GO:0016358//dendrite development;GO:0032100//positive regulation of appetite;GO:0008343//adult feeding behavior;GO:0042536//negative regulation of tumor necrosis factor biosynthetic process;GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0060124//positive regulation of growth hormone secretion;GO:0051216//cartilage development",GO:0016608//growth hormone-releasing hormone activity;GO:0030296//protein tyrosine kinase activator activity;GO:0001664//G-protein coupled receptor binding;GO:0031768//ghrelin receptor binding,-
5174,0,0,0,0,0,0,0,0,28,0,0,0,PDZK1;PDZ domain containing 1,GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0031528//microvillus membrane;GO:0005886//plasma membrane;GO:0031526//brush border membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0090314//positive regulation of protein targeting to membrane;GO:0015893//drug transport;GO:0015879//carnitine transport;GO:0008283//cell proliferation;GO:0006810//transport;GO:0090002//establishment of protein localization to plasma membrane;GO:0044070//regulation of anion transport;GO:0034767//positive regulation of ion transmembrane transport,GO:0005515//protein binding;GO:0005215//transporter activity;GO:0032403//protein complex binding;GO:0005124//scavenger receptor binding;GO:0030165//PDZ domain binding,-
51741,0,25,0,0,4,0,0,110,56,46,14,1,WWOX;WW domain containing oxidoreductase,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005902//microvillus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0016055//Wnt signaling pathway;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0030178//negative regulation of Wnt signaling pathway;GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus,GO:0005515//protein binding;GO:0016491//oxidoreductase activity;GO:0048037//cofactor binding;GO:0019899//enzyme binding;GO:0046983//protein dimerization activity;GO:0050662//coenzyme binding,K13305//Endocytosis;Ubiquitin mediated proteolysis;Aldosterone-regulated sodium reabsorption;K11153//Metabolic pathways;Retinol metabolism;K10591//Ubiquitin mediated proteolysis;Epstein-Barr virus infection;Endocytosis;K05632//Endocytosis;Ubiquitin mediated proteolysis;K05633//Ubiquitin mediated proteolysis;Endocytosis
51742,0,32,244,65,161,15,18,1029,262,0,19,0,ARID4B;AT rich interactive domain 4B (RBP1-like),GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006349//regulation of gene expression by genetic imprinting;GO:0036124//histone H3-K9 trimethylation;GO:0006355//regulation of transcription, DNA-templated;GO:0034773//histone H4-K20 trimethylation",GO:0003677//DNA binding;GO:0005515//protein binding,K07874//Legionellosis
51744,0,0,0,0,0,0,0,4,12,3,0,0,"CD244;CD244 molecule, natural killer cell receptor 2B4",GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0007165//signal transduction,GO:0004872//receptor activity;GO:0005515//protein binding,K06582//Natural killer cell mediated cytotoxicity
51747,0,35,0,6,92,40,1,0,27,0,0,0,LUC7L3;LUC7-like 3 (S. cerevisiae),GO:0005634//nucleus;GO:0005685//U1 snRNP;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0016607//nuclear speck,GO:0006376//mRNA splice site selection;GO:0008380//RNA splicing,GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
5175,0,0,0,0,0,20,0,0,0,0,0,0,PECAM1;platelet/endothelial cell adhesion molecule 1,GO:0031092//platelet alpha granule membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0002576//platelet degranulation;GO:0007155//cell adhesion;GO:0008037//cell recognition;GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0050904//diapedesis;GO:0072011//glomerular endothelium development;GO:0030168//platelet activation;GO:0030198//extracellular matrix organization;GO:0006909//phagocytosis,GO:0005515//protein binding,K06471//Malaria;Cell adhesion molecules (CAMs);Leukocyte transendothelial migration
51751,0,0,0,1,1,0,0,0,0,0,0,0,"HIGD1B;HIG1 hypoxia inducible domain family, member 1B",GO:0016021//integral component of membrane,-,-,-
51752,3,129,257,280,514,9,151,2,132,478,233,0,ERAP1;endoplasmic reticulum aminopeptidase 1,GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0006509//membrane protein ectodomain proteolysis;GO:0008217//regulation of blood pressure;GO:0009617//response to bacterium;GO:0045444//fat cell differentiation;GO:0045088//regulation of innate immune response;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0045766//positive regulation of angiogenesis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0001525//angiogenesis,"GO:0008235//metalloexopeptidase activity;GO:0005151//interleukin-1, Type II receptor binding;GO:0008270//zinc ion binding;GO:0004177//aminopeptidase activity;GO:0005138//interleukin-6 receptor binding;GO:0005515//protein binding",-
51754,0,0,0,0,9,28,25,0,6,0,0,0,TMEM8B;transmembrane protein 8B,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0007346//regulation of mitotic cell cycle;GO:0040008//regulation of growth;GO:0007160//cell-matrix adhesion,GO:0005515//protein binding,-
51755,0,90,0,37,83,65,16,0,28,173,9,0,CDK12;cyclin-dependent kinase 12,GO:0002944//cyclin K-CDK12 complex;GO:0005634//nucleus;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0005730//nucleolus;GO:0016607//nuclear speck,GO:0043405//regulation of MAP kinase activity;GO:0051726//regulation of cell cycle;GO:0046777//protein autophosphorylation;GO:0006397//mRNA processing;GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:0008380//RNA splicing,GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0030332//cyclin binding;GO:0005515//protein binding,-
51759,0,4,0,8,46,0,23,0,7,0,0,0,C9orf78;chromosome 9 open reading frame 78,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
5176,0,0,0,2,0,0,0,0,19,0,23,0,"SERPINF1;serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1",GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0042470//melanosome,GO:0016525//negative regulation of angiogenesis;GO:0007568//aging;GO:0032526//response to retinoic acid;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0051384//response to glucocorticoid;GO:0050769//positive regulation of neurogenesis;GO:0001822//kidney development;GO:0010951//negative regulation of endopeptidase activity;GO:0007614//short-term memory;GO:0030162//regulation of proteolysis;GO:0008283//cell proliferation;GO:0007275//multicellular organismal development;GO:0050728//negative regulation of inflammatory response,GO:0004867//serine-type endopeptidase inhibitor activity,K03983//Complement and coagulation cascades
51760,0,0,0,5,46,0,0,50,0,0,0,0,SYT17;synaptotagmin XVII,GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0005802//trans-Golgi network,GO:0006887//exocytosis,GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
51761,38,0,12,3,0,25,90,235,30,0,6,0,"ATP8A2;ATPase, aminophospholipid transporter, class I, type 8A, member 2",GO:0001750//photoreceptor outer segment;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0010842//retina layer formation;GO:0050908//detection of light stimulus involved in visual perception;GO:0042755//eating behavior;GO:0043588//skin development;GO:0045332//phospholipid translocation;GO:0010996//response to auditory stimulus;GO:0008152//metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0042472//inner ear morphogenesis;GO:0040018//positive regulation of multicellular organism growth;GO:0007568//aging;GO:0007409//axonogenesis;GO:0050884//neuromuscular process controlling posture;GO:0060052//neurofilament cytoskeleton organization;GO:0010976//positive regulation of neuron projection development,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity,-
51762,0,1,0,20,138,0,0,0,33,0,19,0,"RAB8B;RAB8B, member RAS oncogene family",GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm;GO:0045335//phagocytic vesicle;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane;GO:0051286//cell tip,GO:0042384//cilium assembly;GO:0031346//positive regulation of cell projection organization;GO:0006184//GTP catabolic process;GO:0019882//antigen processing and presentation;GO:0034332//adherens junction organization;GO:0007264//small GTPase mediated signal transduction;GO:0045046//protein import into peroxisome membrane;GO:0051461//positive regulation of corticotropin secretion,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005102//receptor binding;GO:0030911//TPR domain binding;GO:0019003//GDP binding;GO:0005515//protein binding,-
51763,101,30,27,20,1,0,0,37,31,0,15,1,INPP5K;inositol polyphosphate-5-phosphatase K,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0032869//cellular response to insulin stimulus;GO:0001933//negative regulation of protein phosphorylation;GO:0090315//negative regulation of protein targeting to membrane;GO:0042593//glucose homeostasis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0071320//cellular response to cAMP;GO:0035305//negative regulation of dephosphorylation;GO:0010829//negative regulation of glucose transport;GO:0071356//cellular response to tumor necrosis factor;GO:0045719//negative regulation of glycogen biosynthetic process;GO:2001153//positive regulation of renal water transport;GO:0097178//ruffle assembly;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0051926//negative regulation of calcium ion transport;GO:0051898//negative regulation of protein kinase B signaling;GO:0051497//negative regulation of stress fiber assembly;GO:0046855//inositol phosphate dephosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016311//dephosphorylation;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0030036//actin cytoskeleton organization;GO:0006469//negative regulation of protein kinase activity;GO:0044281//small molecule metabolic process;GO:0035810//positive regulation of urine volume;GO:0001701//in utero embryonic development;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0043922//negative regulation by host of viral transcription;GO:0072661//protein targeting to plasma membrane;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000466//negative regulation of glycogen (starch) synthase activity;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0005979//regulation of glycogen biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0032870//cellular response to hormone stimulus;GO:0006644//phospholipid metabolic process","GO:0052658//inositol-1,4,5-trisphosphate 5-phosphatase activity;GO:0005000//vasopressin receptor activity;GO:0005515//protein binding;GO:0042577//lipid phosphatase activity;GO:0052659//inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0016312//inositol bisphosphate phosphatase activity;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0034485//phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity",K01106//Phosphatidylinositol signaling system;Metabolic pathways;Insulin signaling pathway;Inositol phosphate metabolism
51764,0,0,0,0,0,0,4,0,9,0,9,0,"GNG13;guanine nucleotide binding protein (G protein), gamma 13",GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0044281//small molecule metabolic process;GO:0050909//sensory perception of taste;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0071377//cellular response to glucagon stimulus,GO:0031681//G-protein beta-subunit binding;GO:0004871//signal transducer activity,K04547//Chemokine signaling pathway;GABAergic synapse;Dopaminergic synapse;Cholinergic synapse;Alcoholism;Retrograde endocannabinoid signaling;Serotonergic synapse;Glutamatergic synapse;Taste transduction;Morphine addiction;Phototransduction - fly
51765,120,0,0,2,22,0,22,0,69,0,0,0,MST4;serine/threonine protein kinase MST4,GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0042802//identical protein binding;GO:0005515//protein binding,-
51768,102,0,1,7,0,30,10,13,38,0,0,1,TM7SF3;transmembrane 7 superfamily member 3,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
51773,1,0,0,22,80,0,0,0,70,0,1,0,RSF1;remodeling and spacing factor 1,GO:0005654//nucleoplasm;GO:0031213//RSF complex;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0016584//nucleosome positioning;GO:0006338//chromatin remodeling;GO:0006352//DNA-templated transcription, initiation;GO:0043392//negative regulation of DNA binding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006334//nucleosome assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0050434//positive regulation of viral transcription",GO:0016887//ATPase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0042393//histone binding,-
51776,67,24,14,11,71,16,30,0,16,0,1,0,ZAK;sterile alpha motif and leucine zipper containing kinase AZK,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007050//cell cycle arrest;GO:0000075//cell cycle checkpoint;GO:0030154//cell differentiation;GO:0008219//cell death;GO:0000077//DNA damage checkpoint;GO:0035556//intracellular signal transduction;GO:0006950//response to stress;GO:0043065//positive regulation of apoptotic process;GO:0007010//cytoskeleton organization;GO:0006468//protein phosphorylation;GO:0009314//response to radiation;GO:0007257//activation of JUN kinase activity;GO:0000186//activation of MAPKK activity;GO:0008283//cell proliferation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K04424//MAPK signaling pathway;Tight junction
51778,0,0,0,0,0,82,0,58,0,0,0,0,MYOZ2;myozenin 2,GO:0015629//actin cytoskeleton;GO:0030018//Z disc;GO:0030017//sarcomere,-,GO:0005515//protein binding;GO:0003779//actin binding;GO:0030346//protein phosphatase 2B binding;GO:0031433//telethonin binding,-
5178,5,0,0,7,56,0,0,0,37,0,4,0,PEG3;paternally expressed 3,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0035264//multicellular organism growth;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0071514//genetic imprinting,GO:0046872//metal ion binding;GO:0003676//nucleic acid binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
51780,1,178,1,106,254,25,1,136,33,0,0,0,KDM3B;lysine (K)-specific demethylase 3B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0055114//oxidation-reduction process;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0051213//dioxygenase activity;GO:0046872//metal ion binding,-
518,0,42,0,4,97,0,0,14,17,0,9,0,"ATP5G3;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)","GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0016021//integral component of membrane",GO:0015991//ATP hydrolysis coupled proton transport;GO:0015986//ATP synthesis coupled proton transport,GO:0008289//lipid binding;GO:0005215//transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity,K02128//Metabolic pathways;Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation
51802,0,0,0,0,8,0,0,0,78,0,0,0,ASIC5;acid-sensing (proton-gated) ion channel family member 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:0015992//proton transport,GO:0015280//ligand-gated sodium channel activity;GO:0015252//hydrogen ion channel activity,-
51804,0,0,1,0,7,12,0,0,35,0,44,0,SIX4;SIX homeobox 4,GO:0005634//nucleus,GO:0009653//anatomical structure morphogenesis;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0072095//regulation of branch elongation involved in ureteric bud branching;GO:0072107//positive regulation of ureteric bud formation;GO:0051451//myoblast migration;GO:0007519//skeletal muscle tissue development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072075//metanephric mesenchyme development;GO:0048538//thymus development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0042472//inner ear morphogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0032880//regulation of protein localization;GO:0048699//generation of neurons,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,K15615//Transcriptional misregulation in cancer
51805,0,0,0,0,0,14,11,0,0,0,0,0,COQ3;coenzyme Q3 methyltransferase,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0032259//methylation;GO:0044281//small molecule metabolic process;GO:0006744//ubiquinone biosynthetic process;GO:0006071//glycerol metabolic process,"GO:0004395//hexaprenyldihydroxybenzoate methyltransferase activity;GO:0008171//O-methyltransferase activity;GO:0008425//2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity;GO:0008689//3-demethylubiquinone-9 3-O-methyltransferase activity",K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
51806,0,0,0,0,0,0,0,65,32,0,0,0,CALML5;calmodulin-like 5,GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0008544//epidermis development,GO:0005509//calcium ion binding,K02183//Phototransduction;Insulin signaling pathway;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Long-term potentiation;Pertussis;Tuberculosis;Alcoholism;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Alzheimer's disease;Neurotrophin signaling pathway;Melanogenesis;Glioma;Gastric acid secretion
51807,0,0,0,0,0,0,13,28,3,0,0,0,"TUBA8;tubulin, alpha 8",GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process;GO:0051258//protein polymerization;GO:0007017//microtubule-based process,GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07374//Pathogenic Escherichia coli infection;Phagosome;Gap junction
51808,96,1,0,32,89,0,1,0,22,0,6,0,PHAX;phosphorylated adaptor for RNA export,GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0043025//neuronal cell body;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0015031//protein transport;GO:0010467//gene expression;GO:0006408//snRNA export from nucleus;GO:0016070//RNA metabolic process,GO:0003723//RNA binding;GO:0015643//toxic substance binding,K14291//RNA transport
51809,0,22,0,14,72,11,0,1,5,0,6,0,GALNT7;polypeptide N-acetylgalactosaminyltransferase 7,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0044267//cellular protein metabolic process;GO:0006493//protein O-linked glycosylation,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
51816,123,0,0,5,0,15,0,90,22,0,29,122,"CECR1;cat eye syndrome chromosome region, candidate 1",GO:0005615//extracellular space;GO:0005829//cytosol,GO:0006154//adenosine catabolic process;GO:0043103//hypoxanthine salvage;GO:0007275//multicellular organismal development;GO:0046103//inosine biosynthetic process,GO:0008270//zinc ion binding;GO:0008083//growth factor activity;GO:0004000//adenosine deaminase activity;GO:0043394//proteoglycan binding;GO:0042803//protein homodimerization activity;GO:0008201//heparin binding;GO:0031685//adenosine receptor binding,K01488//Primary immunodeficiency;Metabolic pathways;Purine metabolism
5184,71,1,0,1,0,16,0,0,1,0,0,0,PEPD;peptidase D,GO:0070062//extracellular vesicular exosome,GO:0030574//collagen catabolic process;GO:0006520//cellular amino acid metabolic process;GO:0006508//proteolysis,GO:0004181//metallocarboxypeptidase activity;GO:0030145//manganese ion binding;GO:0016805//dipeptidase activity;GO:0004177//aminopeptidase activity,-
5187,0,0,0,0,5,23,0,164,0,0,1,1,PER1;period circadian clock 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043966//histone H3 acetylation;GO:0007165//signal transduction;GO:0042634//regulation of hair cycle;GO:0009649//entrainment of circadian clock;GO:0043967//histone H4 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1900744//regulation of p38MAPK cascade;GO:0043153//entrainment of circadian clock by photoperiod;GO:0007623//circadian rhythm;GO:0046329//negative regulation of JNK cascade;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070932//histone H3 deacetylation;GO:1900015//regulation of cytokine production involved in inflammatory response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0097167//circadian regulation of translation;GO:0002028//regulation of sodium ion transport;GO:0010608//posttranscriptional regulation of gene expression;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0070888//E-box binding;GO:0019900//kinase binding;GO:0004871//signal transducer activity;GO:0031490//chromatin DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0000989//transcription factor binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K02633//Circadian rhythm - mammal;Transcriptional misregulation in cancer;Circadian rhythm - fly;Herpes simplex infection
5188,0,0,0,0,0,0,23,3,11,140,7,346,PET112;PET112 homolog (yeast),GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex;GO:0005739//mitochondrion,GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation;GO:0032543//mitochondrial translation;GO:0006412//translation,"GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity;GO:0005524//ATP binding;GO:0008135//translation factor activity, nucleic acid binding",K02434//Metabolic pathways;Aminoacyl-tRNA biosynthesis
5189,143,20,16,40,81,0,32,0,12,0,0,327,PEX1;peroxisomal biogenesis factor 1,GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005778//peroxisomal membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm,GO:0006200//ATP catabolic process;GO:0007031//peroxisome organization;GO:0060152//microtubule-based peroxisome localization;GO:0016558//protein import into peroxisome matrix;GO:0006625//protein targeting to peroxisome,"GO:0042623//ATPase activity, coupled;GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding",K13338//Peroxisome
5190,0,235,28,249,369,0,42,373,38,0,88,0,PEX6;peroxisomal biogenesis factor 6,GO:0005829//cytosol;GO:0005778//peroxisomal membrane;GO:0005777//peroxisome;GO:0005737//cytoplasm,"GO:0050821//protein stabilization;GO:0007031//peroxisome organization;GO:0006200//ATP catabolic process;GO:0016561//protein import into peroxisome matrix, translocation;GO:0006625//protein targeting to peroxisome","GO:0042623//ATPase activity, coupled;GO:0008022//protein C-terminus binding;GO:0032403//protein complex binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0016887//ATPase activity",K13339//Peroxisome
5191,0,0,0,12,42,0,36,0,36,0,13,0,PEX7;peroxisomal biogenesis factor 7,GO:0005829//cytosol;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,GO:0008611//ether lipid biosynthetic process;GO:0007031//peroxisome organization;GO:0001764//neuron migration;GO:0016558//protein import into peroxisome matrix;GO:0006635//fatty acid beta-oxidation;GO:0001958//endochondral ossification,GO:0019899//enzyme binding;GO:0005053//peroxisome matrix targeting signal-2 binding;GO:0042803//protein homodimerization activity,K13341//Peroxisome
5192,0,167,125,227,181,42,0,74,150,0,266,0,PEX10;peroxisomal biogenesis factor 10,GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005622//intracellular,GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008022//protein C-terminus binding,K13346//Peroxisome
5193,0,25,0,0,2,0,0,0,2,0,25,0,PEX12;peroxisomal biogenesis factor 12,GO:0005779//integral component of peroxisomal membrane;GO:0005778//peroxisomal membrane;GO:0005777//peroxisome,GO:0016558//protein import into peroxisome matrix;GO:0006625//protein targeting to peroxisome;GO:0007031//peroxisome organization,GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K13345//Peroxisome
5194,0,3,0,5,51,0,28,0,22,0,0,0,PEX13;peroxisomal biogenesis factor 13,GO:0016020//membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005778//peroxisomal membrane;GO:0005777//peroxisome,"GO:0021795//cerebral cortex cell migration;GO:0016560//protein import into peroxisome matrix, docking;GO:0007626//locomotory behavior;GO:0001764//neuron migration;GO:0001561//fatty acid alpha-oxidation;GO:0060152//microtubule-based peroxisome localization;GO:0001967//suckling behavior",GO:0005515//protein binding,K13344//Peroxisome
5195,0,28,0,0,0,24,0,169,24,39,0,320,PEX14;peroxisomal biogenesis factor 14,GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0043234//protein complex;GO:0005777//peroxisome;GO:0005622//intracellular;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,"GO:0016561//protein import into peroxisome matrix, translocation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016558//protein import into peroxisome matrix;GO:0036250//peroxisome transport along microtubule;GO:0032091//negative regulation of protein binding;GO:0007031//peroxisome organization;GO:0006461//protein complex assembly;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051260//protein homooligomerization;GO:0044721//protein import into peroxisome matrix, substrate release;GO:0034453//microtubule anchoring;GO:1901094//negative regulation of protein homotetramerization",GO:0003714//transcription corepressor activity;GO:0047485//protein N-terminus binding;GO:0005102//receptor binding;GO:0048487//beta-tubulin binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K13343//Peroxisome
5196,0,0,0,0,0,0,0,0,28,0,0,0,PF4;platelet factor 4,GO:0005576//extracellular region;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space,GO:0030168//platelet activation;GO:0016525//negative regulation of angiogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0030595//leukocyte chemotaxis;GO:0002576//platelet degranulation;GO:0045653//negative regulation of megakaryocyte differentiation;GO:0019221//cytokine-mediated signaling pathway;GO:0045918//negative regulation of cytolysis;GO:0007596//blood coagulation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0032760//positive regulation of tumor necrosis factor production;GO:0045651//positive regulation of macrophage differentiation;GO:0030816//positive regulation of cAMP metabolic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045347//negative regulation of MHC class II biosynthetic process;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0010628//positive regulation of gene expression;GO:0006955//immune response,GO:0008201//heparin binding;GO:0008009//chemokine activity;GO:0048248//CXCR3 chemokine receptor binding,K05407//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
5197,0,0,0,0,0,0,0,0,29,0,9,0,PF4V1;platelet factor 4 variant 1,GO:0005615//extracellular space,GO:0006955//immune response;GO:0060326//cell chemotaxis,GO:0008009//chemokine activity;GO:0008201//heparin binding,K05407//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
5198,23,0,0,1,17,7,0,0,31,0,3,0,PFAS;phosphoribosylformylglycinamidine synthase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0006189//'de novo' IMP biosynthetic process;GO:0006541//glutamine metabolic process;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006144//purine nucleobase metabolic process,GO:0046872//metal ion binding;GO:0004642//phosphoribosylformylglycinamidine synthase activity;GO:0005524//ATP binding,K01952//Purine metabolism;Phosphotransferase system (PTS);Biosynthesis of secondary metabolites;Metabolic pathways;Fructose and mannose metabolism
5199,83,0,0,0,0,0,0,0,0,0,0,0,CFP;complement factor properdin,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0031012//extracellular matrix,"GO:0045087//innate immune response;GO:0006955//immune response;GO:0006956//complement activation;GO:0006957//complement activation, alternative pathway;GO:0030449//regulation of complement activation;GO:0042742//defense response to bacterium",-,K15412//Herpes simplex infection
52,0,1,1,10,135,12,22,0,0,0,0,0,"ACP1;acid phosphatase 1, soluble",GO:0005737//cytoplasm;GO:0009898//cytoplasmic side of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0005515//protein binding;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0003993//acid phosphatase activity,K14394//Riboflavin metabolism;Adherens junction
5202,0,27,0,0,1,0,16,0,7,0,0,0,PFDN2;prefoldin subunit 2,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0016272//prefoldin complex;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process,GO:0051082//unfolded protein binding;GO:0005515//protein binding,-
5203,0,0,0,0,0,0,0,0,7,0,7,0,PFDN4;prefoldin subunit 4,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016272//prefoldin complex;GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding,GO:0051087//chaperone binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding,-
5204,0,143,1,90,180,0,40,0,0,0,0,0,PFDN5;prefoldin subunit 5,GO:0016272//prefoldin complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060041//retina development in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0044267//cellular protein metabolic process",GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0051082//unfolded protein binding,-
5205,1,0,0,24,58,0,46,0,66,0,42,1,"ATP8B1;ATPase, aminophospholipid transporter, class I, type 8B, member 1",GO:0005886//plasma membrane;GO:0031526//brush border membrane;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0032420//stereocilium;GO:0005887//integral component of plasma membrane,"GO:0008206//bile acid metabolic process;GO:0021650//vestibulocochlear nerve formation;GO:0055085//transmembrane transport;GO:0032534//regulation of microvillus assembly;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport;GO:0006855//drug transmembrane transport;GO:0060119//inner ear receptor cell development;GO:0015721//bile acid and bile salt transport;GO:0007605//sensory perception of sound",GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:1901612//cardiolipin binding,K01530//Purine metabolism
5207,4,0,1,0,38,0,7,0,9,112,37,0,"PFKFB1;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1","GO:0043540//6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex;GO:0005829//cytosol","GO:0005975//carbohydrate metabolic process;GO:0051591//response to cAMP;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006112//energy reserve metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0031100//organ regeneration;GO:0051384//response to glucocorticoid;GO:0032868//response to insulin;GO:0044281//small molecule metabolic process;GO:0016311//dephosphorylation;GO:0042594//response to starvation;GO:0033762//response to glucagon;GO:0006094//gluconeogenesis;GO:0035556//intracellular signal transduction;GO:0006000//fructose metabolic process;GO:0033133//positive regulation of glucokinase activity","GO:0070095//fructose-6-phosphate binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0019900//kinase binding;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524//ATP binding;GO:0003873//6-phosphofructo-2-kinase activity",K01103//Fructose and mannose metabolism
5208,0,0,3,72,79,33,45,0,100,0,6,0,"PFKFB2;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2",GO:0005829//cytosol,"GO:0006000//fructose metabolic process;GO:0033133//positive regulation of glucokinase activity;GO:0046835//carbohydrate phosphorylation;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0006089//lactate metabolic process;GO:0016311//dephosphorylation;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0006007//glucose catabolic process;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose;GO:0005975//carbohydrate metabolic process","GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0005524//ATP binding;GO:0003873//6-phosphofructo-2-kinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding",K01103//Fructose and mannose metabolism
5209,0,0,0,0,0,0,14,1,16,0,1,582,"PFKFB3;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3",GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0006000//fructose metabolic process;GO:0016311//dephosphorylation;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process","GO:0005524//ATP binding;GO:0003873//6-phosphofructo-2-kinase activity;GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity",K01103//Fructose and mannose metabolism
521,0,0,0,11,1,0,0,0,0,0,0,0,"ATP5I;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E","GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)",GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process,GO:0016887//ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0022857//transmembrane transporter activity,K02129//Oxidative phosphorylation;Metabolic pathways
5210,0,0,0,0,16,37,25,28,50,0,0,1,"PFKFB4;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4",GO:0005829//cytosol,"GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006003//fructose 2,6-bisphosphate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0006000//fructose metabolic process;GO:0016311//dephosphorylation","GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity;GO:0003873//6-phosphofructo-2-kinase activity;GO:0005524//ATP binding",K01103//Fructose and mannose metabolism
5211,62,1,1,1,21,6,13,3,33,0,0,209,"PFKL;phosphofructokinase, liver",GO:0005945//6-phosphofructokinase complex;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0030388//fructose 1,6-bisphosphate metabolic process;GO:0009749//response to glucose;GO:0051259//protein oligomerization;GO:0005975//carbohydrate metabolic process;GO:0051289//protein homotetramerization;GO:0046835//carbohydrate phosphorylation;GO:0046676//negative regulation of insulin secretion",GO:0019900//kinase binding;GO:0003872//6-phosphofructokinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070061//fructose binding;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0070095//fructose-6-phosphate binding,K00850//Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Methane metabolism;Biosynthesis of secondary metabolites;Fructose and mannose metabolism;Metabolic pathways;Galactose metabolism;Pentose phosphate pathway
5212,0,0,0,0,0,17,38,1,30,0,12,0,VIT;vitrin,GO:0005614//interstitial matrix,GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization,GO:0005539//glycosaminoglycan binding,K06560//Phagosome;Tuberculosis;K06238//ECM-receptor interaction;Protein digestion and absorption;Focal adhesion
5213,0,1,41,16,51,0,28,272,56,0,44,0,"PFKM;phosphofructokinase, muscle",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0097228//sperm principal piece;GO:0016324//apical plasma membrane;GO:0005945//6-phosphofructokinase complex,GO:0046716//muscle cell cellular homeostasis;GO:0046835//carbohydrate phosphorylation;GO:0042593//glucose homeostasis;GO:0051259//protein oligomerization;GO:0005975//carbohydrate metabolic process;GO:0032024//positive regulation of insulin secretion;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008022//protein C-terminus binding;GO:0019900//kinase binding;GO:0003872//6-phosphofructokinase activity;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0070061//fructose binding,K00850//Microbial metabolism in diverse environments;Methane metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Metabolic pathways;Pentose phosphate pathway;Galactose metabolism;Fructose and mannose metabolism
5214,0,0,0,0,19,35,16,1,68,0,0,0,"PFKP;phosphofructokinase, platelet",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0003872//6-phosphofructokinase activity,K00850//Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Fructose and mannose metabolism;Galactose metabolism;Pentose phosphate pathway;Metabolic pathways
5216,0,72,2,15,60,0,0,137,35,0,0,0,PFN1;profilin 1,GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0016020//membrane;GO:0072562//blood microparticle;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:1900029//positive regulation of ruffle assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0051497//negative regulation of stress fiber assembly;GO:0008219//cell death;GO:0032781//positive regulation of ATPase activity;GO:0030837//negative regulation of actin filament polymerization;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032232//negative regulation of actin filament bundle assembly;GO:0030168//platelet activation;GO:0001843//neural tube closure;GO:0030036//actin cytoskeleton organization;GO:0007596//blood coagulation;GO:0010634//positive regulation of epithelial cell migration;GO:0002576//platelet degranulation,"GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0017048//Rho GTPase binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0003779//actin binding",K05759//Shigellosis;Salmonella infection;Regulation of actin cytoskeleton
5217,0,99,1,94,332,0,8,0,0,0,9,0,PFN2;profilin 2,GO:0070062//extracellular vesicular exosome;GO:0043195//terminal bouton;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0030837//negative regulation of actin filament polymerization;GO:0030838//positive regulation of actin filament polymerization;GO:0051496//positive regulation of stress fiber assembly;GO:0032781//positive regulation of ATPase activity;GO:2000300//regulation of synaptic vesicle exocytosis;GO:0032233//positive regulation of actin filament bundle assembly;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:1900028//negative regulation of ruffle assembly;GO:0030036//actin cytoskeleton organization;GO:0010633//negative regulation of epithelial cell migration,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0003785//actin monomer binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0005515//protein binding",K05759//Shigellosis;Regulation of actin cytoskeleton;Salmonella infection
5218,0,1,0,12,69,35,15,0,13,0,5,0,CDK14;cyclin-dependent kinase 14,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0000308//cytoplasmic cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm,GO:0060828//regulation of canonical Wnt signaling pathway;GO:0006468//protein phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0016055//Wnt signaling pathway;GO:0051301//cell division,GO:0030332//cyclin binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,K08821//Transcriptional misregulation in cancer
522,0,105,18,115,143,2,0,258,29,0,127,1,"ATP5J;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6","GO:0000276//mitochondrial proton-transporting ATP synthase complex, coupling factor F(o);GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane",GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0006200//ATP catabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain,GO:0016887//ATPase activity;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005215//transporter activity;GO:0022857//transmembrane transporter activity,K02131//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
5222,0,0,0,0,0,0,0,0,0,0,7,0,"PGA5;pepsinogen 5, group I (pepsinogen A)",GO:0070062//extracellular vesicular exosome,GO:0007586//digestion;GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity,K06002//Protein digestion and absorption
5223,196,105,1,0,38,0,0,0,24,0,0,0,PGAM1;phosphoglycerate mutase 1 (brain),GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0016311//dephosphorylation;GO:0006094//gluconeogenesis;GO:0045730//respiratory burst;GO:0005975//carbohydrate metabolic process;GO:0006110//regulation of glycolytic process;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0043456//regulation of pentose-phosphate shunt;GO:0044281//small molecule metabolic process,GO:0004083//bisphosphoglycerate 2-phosphatase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,"K01834//Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Metabolic pathways"
5224,0,0,1,17,37,0,0,0,4,0,74,0,PGAM2;phosphoglycerate mutase 2 (muscle),GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0005975//carbohydrate metabolic process;GO:0006941//striated muscle contraction;GO:0044281//small molecule metabolic process;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0006094//gluconeogenesis;GO:0046689//response to mercury ion;GO:0016311//dephosphorylation;GO:0007283//spermatogenesis,"GO:0048037//cofactor binding;GO:0046538//2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity;GO:0004083//bisphosphoglycerate 2-phosphatase activity;GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity","K01834//Glycine, serine and threonine metabolism;Glycolysis / Gluconeogenesis;Methane metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Microbial metabolism in diverse environments"
5225,0,12,0,0,0,0,0,0,24,0,1,0,PGC;progastricsin (pepsinogen C),GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0007586//digestion,GO:0004190//aspartic-type endopeptidase activity,-
5226,0,67,0,21,70,7,10,0,38,0,2,0,PGD;phosphogluconate dehydrogenase,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0019322//pentose biosynthetic process;GO:0006098//pentose-phosphate shunt;GO:0019521//D-gluconate metabolic process;GO:0055114//oxidation-reduction process;GO:0009051//pentose-phosphate shunt, oxidative branch;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process",GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity;GO:0050661//NADP binding,"K00033//Glutathione metabolism;Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;Metabolic pathways;Microbial metabolism in diverse environments;Aminoacyl-tRNA biosynthesis;Pentose phosphate pathway"
5228,0,23,0,0,0,0,0,0,30,0,0,0,PGF;placental growth factor,GO:0005576//extracellular region;GO:0016020//membrane;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0051781//positive regulation of cell division;GO:0030154//cell differentiation;GO:0032870//cellular response to hormone stimulus;GO:0001666//response to hypoxia;GO:0060688//regulation of morphogenesis of a branching structure;GO:0002040//sprouting angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0007267//cell-cell signaling;GO:0031100//organ regeneration;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0008284//positive regulation of cell proliferation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0048010//vascular endothelial growth factor receptor signaling pathway,GO:0008083//growth factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0008201//heparin binding;GO:0005515//protein binding,K05448//mTOR signaling pathway;Cytokine-cytokine receptor interaction;Renal cell carcinoma;VEGF signaling pathway;Focal adhesion;Bladder cancer;Rheumatoid arthritis;Pancreatic cancer;Pathways in cancer
5229,0,14,0,75,119,0,0,0,20,0,0,0,"PGGT1B;protein geranylgeranyltransferase type I, beta subunit",GO:0005953//CAAX-protein geranylgeranyltransferase complex,GO:0008284//positive regulation of cell proliferation;GO:0034097//response to cytokine;GO:0045787//positive regulation of cell cycle;GO:0018344//protein geranylgeranylation;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process,GO:0004662//CAAX-protein geranylgeranyltransferase activity;GO:0008270//zinc ion binding,-
523,0,70,3,88,351,12,25,66,59,0,0,1,"ATP6V1A;ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A","GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0005765//lysosomal membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0033180//proton-transporting V-type ATPase, V1 domain",GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006810//transport;GO:0046034//ATP metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport,"GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0005524//ATP binding",K02145//Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Synaptic vesicle cycle;Metabolic pathways;Oxidative phosphorylation;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection
5230,0,83,17,44,132,0,0,0,27,0,10,0,PGK1;phosphoglycerate kinase 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0030855//epithelial cell differentiation;GO:0006096//glycolytic process;GO:0006094//gluconeogenesis;GO:0016310//phosphorylation;GO:0005975//carbohydrate metabolic process,GO:0005524//ATP binding;GO:0004618//phosphoglycerate kinase activity;GO:0005515//protein binding,K00927//Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Metabolic pathways
5232,0,19,1,0,0,0,0,0,32,0,0,0,PGK2;phosphoglycerate kinase 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0035686//sperm fibrous sheath,GO:0016310//phosphorylation;GO:0006096//glycolytic process;GO:0030317//sperm motility,GO:0005524//ATP binding;GO:0004618//phosphoglycerate kinase activity,K00927//Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites
5236,0,35,43,1,20,27,36,0,24,0,11,0,PGM1;phosphoglucomutase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0005975//carbohydrate metabolic process;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019388//galactose catabolic process;GO:0006094//gluconeogenesis;GO:0005980//glycogen catabolic process,GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity,K01835//Purine metabolism;Galactose metabolism;Pentose phosphate pathway;Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Streptomycin biosynthesis
5238,0,184,53,148,397,0,28,0,24,0,132,0,PGM3;phosphoglucomutase 3,GO:0005829//cytosol,GO:0018279//protein N-linked glycosylation via asparagine;GO:0006041//glucosamine metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0007283//spermatogenesis;GO:0030097//hemopoiesis;GO:0019255//glucose 1-phosphate metabolic process,GO:0004614//phosphoglucomutase activity;GO:0000287//magnesium ion binding;GO:0004610//phosphoacetylglucosamine mutase activity,K01836//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
5239,0,0,0,8,66,0,6,0,59,76,22,0,PGM5;phosphoglucomutase 5,GO:0043034//costamere;GO:0009898//cytoplasmic side of plasma membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0014704//intercalated disc;GO:0030018//Z disc;GO:0005913//cell-cell adherens junction;GO:0005829//cytosol;GO:0005914//spot adherens junction;GO:0005925//focal adhesion;GO:0042383//sarcolemma;GO:0001725//stress fiber,GO:0019388//galactose catabolic process;GO:0005978//glycogen biosynthetic process;GO:0007155//cell adhesion;GO:0006006//glucose metabolic process,GO:0004614//phosphoglucomutase activity;GO:0005198//structural molecule activity;GO:0000287//magnesium ion binding,-
5241,4,0,0,0,11,14,68,0,12,0,14,0,PGR;progesterone receptor,GO:0005654//nucleoplasm;GO:0005741//mitochondrial outer membrane,GO:0007267//cell-cell signaling;GO:0060748//tertiary branching involved in mammary gland duct morphogenesis;GO:0010629//negative regulation of gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050847//progesterone receptor signaling pathway;GO:0007165//signal transduction;GO:0001542//ovulation from ovarian follicle;GO:0043401//steroid hormone mediated signaling pathway;GO:0050678//regulation of epithelial cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0002070//epithelial cell maturation,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005102//receptor binding;GO:0005496//steroid binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0003677//DNA binding,K08556//Oocyte meiosis;Progesterone-mediated oocyte maturation
5243,1,0,0,0,0,18,37,0,68,0,0,0,"ABCB1;ATP-binding cassette, sub-family B (MDR/TAP), member 1",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane,GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0042493//response to drug;GO:0072089//stem cell proliferation;GO:0042908//xenobiotic transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0055085//transmembrane transport;GO:0006855//drug transmembrane transport;GO:0006810//transport,"GO:0005524//ATP binding;GO:0005215//transporter activity;GO:0008559//xenobiotic-transporting ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005515//protein binding",K05658//Bile secretion;ABC transporters
5244,0,36,0,0,22,15,13,58,9,0,0,0,"ABCB4;ATP-binding cassette, sub-family B (MDR/TAP), member 4",GO:0046581//intercellular canaliculus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0006855//drug transmembrane transport;GO:0006810//transport;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0044255//cellular lipid metabolic process;GO:0006629//lipid metabolic process;GO:0042493//response to drug,"GO:0008559//xenobiotic-transporting ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding",K05659//Bile secretion;ABC transporters
5245,0,41,2,17,56,24,0,0,11,0,0,0,PHB;prohibitin,GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0042981//regulation of apoptotic process;GO:0001649//osteoblast differentiation;GO:0007165//signal transduction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071354//cellular response to interleukin-6;GO:0016575//histone deacetylation;GO:0006260//DNA replication;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0050847//progesterone receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008285//negative regulation of cell proliferation",GO:0044212//transcription regulatory region DNA binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0005515//protein binding,-
525,0,0,0,0,0,15,0,0,32,0,0,283,"ATP6V1B1;ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1","GO:0016328//lateral plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0012505//endomembrane system;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0033180//proton-transporting V-type ATPase, V1 domain",GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0055074//calcium ion homeostasis;GO:0046034//ATP metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0006885//regulation of pH;GO:0033572//transferrin transport;GO:0042472//inner ear morphogenesis;GO:0001503//ossification;GO:0007605//sensory perception of sound;GO:0045851//pH reduction;GO:0055085//transmembrane transport;GO:0015992//proton transport;GO:0007588//excretion,"GO:0015078//hydrogen ion transmembrane transporter activity;GO:0016820//hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;GO:0032403//protein complex binding;GO:0005524//ATP binding",K02147//Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Synaptic vesicle cycle;Oxidative phosphorylation;Metabolic pathways;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection
5250,0,33,0,49,99,0,1,0,1,0,1,0,"SLC25A3;solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3",GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0006091//generation of precursor metabolites and energy;GO:0006810//transport;GO:0035435//phosphate ion transmembrane transport,GO:0032403//protein complex binding;GO:0015293//symporter activity;GO:0015320//phosphate ion carrier activity,-
5251,312,0,0,0,0,0,20,39,49,141,8,0,"PHEX;phosphate regulating endopeptidase homolog, X-linked",GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0030282//bone mineralization;GO:0006508//proteolysis;GO:0019637//organophosphate metabolic process;GO:0001501//skeletal system development;GO:0007267//cell-cell signaling;GO:0006464//cellular protein modification process,GO:0004222//metalloendopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
5252,0,0,0,1,27,0,0,0,0,0,0,0,PHF1;PHD finger protein 1,GO:0035861//site of double-strand break;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0005815//microtubule organizing center,"GO:0061086//negative regulation of histone H3-K27 methylation;GO:0016568//chromatin modification;GO:0061087//positive regulation of histone H3-K27 methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0035064//methylated histone binding,-
5253,22,34,0,36,39,0,53,0,86,0,0,0,PHF2;PHD finger protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0061188//negative regulation of chromatin silencing at rDNA;GO:0006482//protein demethylation;GO:0055114//oxidation-reduction process;GO:0033169//histone H3-K9 demethylation;GO:0001889//liver development",GO:0005506//iron ion binding;GO:0035064//methylated histone binding;GO:0032452//histone demethylase activity;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0051213//dioxygenase activity;GO:0032454//histone demethylase activity (H3-K9 specific),-
5255,34,110,0,3,55,35,16,0,27,0,0,0,"PHKA1;phosphorylase kinase, alpha 1 (muscle)",GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0006468//protein phosphorylation,"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005516//calmodulin binding;GO:0004689//phosphorylase kinase activity",K07190//Calcium signaling pathway;Insulin signaling pathway
5256,0,41,23,85,29,38,33,160,117,0,219,49,"PHKA2;phosphorylase kinase, alpha 2 (liver)",GO:0005964//phosphorylase kinase complex;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation;GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process,"GO:0005516//calmodulin binding;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004689//phosphorylase kinase activity",K07190//Insulin signaling pathway;Calcium signaling pathway
5257,58,12,0,150,317,35,58,0,34,0,0,255,"PHKB;phosphorylase kinase, beta",GO:0005964//phosphorylase kinase complex;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006006//glucose metabolic process;GO:0005980//glycogen catabolic process;GO:0006468//protein phosphorylation;GO:0005977//glycogen metabolic process;GO:0044281//small molecule metabolic process,"GO:0005515//protein binding;GO:0004689//phosphorylase kinase activity;GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0005516//calmodulin binding",K07190//Calcium signaling pathway;Insulin signaling pathway
526,54,0,5,29,78,0,16,1,49,0,5,0,"ATP6V1B2;ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2","GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005902//microvillus;GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0012505//endomembrane system;GO:0042470//melanosome;GO:0001726//ruffle;GO:0016021//integral component of membrane",GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0015992//proton transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0046034//ATP metabolic process,"GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005524//ATP binding",K02147//Synaptic vesicle cycle;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Metabolic pathways;Oxidative phosphorylation
5260,0,159,192,118,189,32,0,141,10,0,75,0,"PHKG1;phosphorylase kinase, gamma 1 (muscle)",GO:0005829//cytosol;GO:0005964//phosphorylase kinase complex,GO:0005975//carbohydrate metabolic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006468//protein phosphorylation;GO:0005980//glycogen catabolic process,GO:0050321//tau-protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0004689//phosphorylase kinase activity,K00871//Calcium signaling pathway;Insulin signaling pathway
5261,0,0,0,25,6,0,12,0,8,0,2,0,"PHKG2;phosphorylase kinase, gamma 2 (testis)",GO:0005964//phosphorylase kinase complex;GO:0005829//cytosol,GO:0006091//generation of precursor metabolites and energy;GO:0006468//protein phosphorylation;GO:0005980//glycogen catabolic process;GO:0045819//positive regulation of glycogen catabolic process;GO:0005977//glycogen metabolic process;GO:0005975//carbohydrate metabolic process;GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process,GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0004689//phosphorylase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0050321//tau-protein kinase activity,K00871//Calcium signaling pathway;Insulin signaling pathway
5264,0,0,0,0,13,8,14,0,40,0,0,0,PHYH;phytanoyl-CoA 2-hydroxylase,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0006720//isoprenoid metabolic process;GO:0001561//fatty acid alpha-oxidation;GO:0097089//methyl-branched fatty acid metabolic process;GO:0044255//cellular lipid metabolic process,GO:0048037//cofactor binding;GO:0009055//electron carrier activity;GO:0048244//phytanoyl-CoA dioxygenase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0031418//L-ascorbic acid binding,K00477//Peroxisome
5265,0,0,0,0,0,11,11,0,29,0,0,0,"SERPINA1;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1",GO:0005578//proteinaceous extracellular matrix;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030168//platelet activation;GO:0002576//platelet degranulation;GO:0030162//regulation of proteolysis;GO:0006953//acute-phase response;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0002020//protease binding;GO:0001948//glycoprotein binding,K03984//Complement and coagulation cascades
5267,0,0,0,0,0,0,0,0,22,0,0,0,"SERPINA4;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03984//Complement and coagulation cascades
5268,0,0,0,0,99,0,16,74,28,274,0,0,"SERPINB5;serpin peptidase inhibitor, clade B (ovalbumin), member 5",GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0006928//cellular component movement;GO:0030162//regulation of proteolysis;GO:0060512//prostate gland morphogenesis;GO:0002009//morphogenesis of an epithelium;GO:0010951//negative regulation of endopeptidase activity;GO:0050678//regulation of epithelial cell proliferation;GO:0030198//extracellular matrix organization,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K10139//p53 signaling pathway
5269,123,0,0,0,1,11,0,0,7,0,1,0,"SERPINB6;serpin peptidase inhibitor, clade B (ovalbumin), member 6",GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0002020//protease binding,K13963//Amoebiasis
527,0,0,0,0,0,0,0,0,61,0,0,0,"ATP6V0C;ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c","GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain;GO:0005925//focal adhesion;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome",GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0016032//viral process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0015992//proton transport,"GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0031625//ubiquitin protein ligase binding;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism",K02155//Oxidative phosphorylation;Metabolic pathways;Vibrio cholerae infection;Lysosome;Epithelial cell signaling in Helicobacter pylori infection;Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Tuberculosis;Synaptic vesicle cycle
5270,0,0,0,0,0,0,23,0,13,0,0,0,"SERPINE2;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2",GO:0031594//neuromuscular junction;GO:0005576//extracellular region;GO:0031232//extrinsic component of external side of plasma membrane;GO:0031982//vesicle;GO:0031091//platelet alpha granule;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0031012//extracellular matrix,"GO:0030195//negative regulation of blood coagulation;GO:0048711//positive regulation of astrocyte differentiation;GO:0042177//negative regulation of protein catabolic process;GO:0060291//long-term synaptic potentiation;GO:0042628//mating plug formation;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:0060384//innervation;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0030334//regulation of cell migration;GO:0032940//secretion by cell;GO:0061108//seminal vesicle epithelium development;GO:0090331//negative regulation of platelet aggregation;GO:0010766//negative regulation of sodium ion transport;GO:0010955//negative regulation of protein processing;GO:0033363//secretory granule organization;GO:0045879//negative regulation of smoothened signaling pathway;GO:0030308//negative regulation of cell growth;GO:0008285//negative regulation of cell proliferation;GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0010544//negative regulation of platelet activation;GO:0010757//negative regulation of plasminogen activation;GO:0048505//regulation of timing of cell differentiation;GO:0021683//cerebellar granular layer morphogenesis;GO:0045861//negative regulation of proteolysis",GO:0005539//glycosaminoglycan binding;GO:0005102//receptor binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0008201//heparin binding,K03982//Complement and coagulation cascades;p53 signaling pathway;Chagas disease (American trypanosomiasis)
5271,0,0,0,0,0,0,0,0,39,0,0,11,"SERPINB8;serpin peptidase inhibitor, clade B (ovalbumin), member 8",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5272,0,0,0,0,0,18,77,4,14,0,2,0,"SERPINB9;serpin peptidase inhibitor, clade B (ovalbumin), member 9",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010951//negative regulation of endopeptidase activity;GO:0006955//immune response;GO:0030162//regulation of proteolysis;GO:0043066//negative regulation of apoptotic process;GO:0071391//cellular response to estrogen stimulus;GO:0002448//mast cell mediated immunity,GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding,K13963//Amoebiasis
5273,0,0,0,0,0,12,0,0,0,0,0,0,"SERPINB10;serpin peptidase inhibitor, clade B (ovalbumin), member 10",GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5274,0,0,0,0,0,19,17,0,4,50,15,0,"SERPINI1;serpin peptidase inhibitor, clade I (neuroserpin), member 1",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0030155//regulation of cell adhesion;GO:0008219//cell death;GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0007422//peripheral nervous system development;GO:0007417//central nervous system development,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5275,0,0,0,0,0,0,0,0,9,0,0,0,"SERPINB13;serpin peptidase inhibitor, clade B (ovalbumin), member 13",GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0009411//response to UV,GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5276,0,0,0,0,0,0,0,0,44,0,0,0,"SERPINI2;serpin peptidase inhibitor, clade I (pancpin), member 2",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0030155//regulation of cell adhesion;GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0006928//cellular component movement,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K13963//Amoebiasis
5277,0,0,0,9,25,0,0,0,15,0,0,0,"PIGA;phosphatidylinositol glycan anchor biosynthesis, class A",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,GO:0043687//post-translational protein modification;GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0009893//positive regulation of metabolic process,GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity;GO:0005515//protein binding,K03857//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
5279,0,0,0,1,23,0,0,34,12,0,4,0,"PIGC;phosphatidylinositol glycan anchor biosynthesis, class C",GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane,GO:0003824//catalytic activity;GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity,K03859//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
528,0,87,2,4,43,3,0,0,39,0,2,0,"ATP6V1C1;ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1","GO:0045177//apical part of cell;GO:0031410//cytoplasmic vesicle;GO:0005765//lysosomal membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016469//proton-transporting two-sector ATPase complex;GO:0005829//cytosol;GO:0033180//proton-transporting V-type ATPase, V1 domain",GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0051701//interaction with host;GO:0055085//transmembrane transport;GO:0008286//insulin receptor signaling pathway;GO:0015992//proton transport,"GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0005215//transporter activity;GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism",K02148//Synaptic vesicle cycle;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Metabolic pathways;Oxidative phosphorylation
5281,0,16,55,266,189,0,0,0,12,0,162,0,"PIGF;phosphatidylinositol glycan anchor biosynthesis, class F",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0016254//preassembly of GPI anchor in ER membrane;GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation,GO:0004307//ethanolaminephosphotransferase activity,K05287//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
5283,0,0,0,44,95,0,0,0,24,0,20,0,"PIGH;phosphatidylinositol glycan anchor biosynthesis, class H",GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006506//GPI anchor biosynthetic process;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0006464//cellular protein modification process,GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity;GO:0003824//catalytic activity,K03858//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
5284,0,0,0,0,0,48,18,0,14,0,0,0,PIGR;polymeric immunoglobulin receptor,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane,GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001895//retina homeostasis;GO:0043113//receptor clustering;GO:0038093//Fc receptor signaling pathway,GO:0001792//polymeric immunoglobulin receptor activity,K13073//Intestinal immune network for IgA production
5286,107,68,3,110,349,2,0,47,84,0,0,1,"PIK3C2A;phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha",GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005634//nucleus;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0031982//vesicle;GO:0005737//cytoplasm,GO:0014829//vascular smooth muscle contraction;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0006897//endocytosis;GO:0006887//exocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0048268//clathrin coat assembly;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0006644//phospholipid metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0044281//small molecule metabolic process,GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0005524//ATP binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0035091//phosphatidylinositol binding,K00923//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
5287,69,0,1,20,36,42,0,0,57,0,11,1,"PIK3C2B;phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta",GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0030139//endocytic vesicle;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,GO:0043491//protein kinase B signaling;GO:0006644//phospholipid metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process,GO:0035091//phosphatidylinositol binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0005515//protein binding;GO:0001727//lipid kinase activity;GO:0005524//ATP binding;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity,K00923//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
5288,105,0,0,0,0,35,4,0,33,40,9,0,"PIK3C2G;phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex,GO:0006935//chemotaxis;GO:0006644//phospholipid metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process,GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0035091//phosphatidylinositol binding;GO:0016307//phosphatidylinositol phosphate kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0005524//ATP binding,K00923//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
5289,0,53,0,6,51,0,0,0,0,0,17,0,"PIK3C3;phosphatidylinositol 3-kinase, catalytic subunit type 3",GO:0005930//axoneme;GO:0005770//late endosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0030496//midbody;GO:0045335//phagocytic vesicle,GO:0045087//innate immune response;GO:0044281//small molecule metabolic process;GO:0002224//toll-like receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0000910//cytokinesis;GO:0000045//autophagic vacuole assembly;GO:0016485//protein processing;GO:0006644//phospholipid metabolic process;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0050708//regulation of protein secretion;GO:0007032//endosome organization;GO:0045022//early endosome to late endosome transport;GO:0008286//insulin receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006468//protein phosphorylation;GO:0046854//phosphatidylinositol phosphorylation;GO:0043201//response to leucine,GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K00914//Inositol phosphate metabolism;Tuberculosis;Phagosome;Metabolic pathways;Regulation of autophagy;Phosphatidylinositol signaling system
529,0,111,1,44,58,0,0,0,28,0,15,0,"ATP6V1E1;ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016469//proton-transporting two-sector ATPase complex;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005902//microvillus;GO:0005765//lysosomal membrane;GO:0016324//apical plasma membrane,GO:0015991//ATP hydrolysis coupled proton transport;GO:0006879//cellular iron ion homeostasis;GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0008152//metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0015992//proton transport,"GO:0051117//ATPase binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0005515//protein binding;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism",K02150//Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Oxidative phosphorylation;Metabolic pathways;Synaptic vesicle cycle;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome
5290,0,20,0,15,50,48,0,0,65,0,0,0,"PIK3CA;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha","GO:0005943//phosphatidylinositol 3-kinase complex, class IA;GO:0030027//lamellipodium;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005886//plasma membrane",GO:2000653//regulation of genetic imprinting;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006644//phospholipid metabolic process;GO:0043542//endothelial cell migration;GO:0045860//positive regulation of protein kinase activity;GO:0006006//glucose metabolic process;GO:0050900//leukocyte migration;GO:2000811//negative regulation of anoikis;GO:0048015//phosphatidylinositol-mediated signaling;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0043491//protein kinase B signaling;GO:0045087//innate immune response;GO:0060048//cardiac muscle contraction;GO:0001525//angiogenesis;GO:0007596//blood coagulation;GO:0008286//insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0001944//vasculature development;GO:0044029//hypomethylation of CpG island;GO:0006661//phosphatidylinositol biosynthetic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0030168//platelet activation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process,"GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0030295//protein kinase activator activity;GO:0043560//insulin receptor substrate binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0016301//kinase activity;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0005524//ATP binding",K00922//Bacterial invasion of epithelial cells;HTLV-I infection;Jak-STAT signaling pathway;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;Endometrial cancer;Toxoplasmosis;Osteoclast differentiation;Focal adhesion;Inositol phosphate metabolism;VEGF signaling pathway;Glioma;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Toll-like receptor signaling pathway;Influenza A;mTOR signaling pathway;Apoptosis;Renal cell carcinoma;Epstein-Barr virus infection;ErbB signaling pathway;Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;Neurotrophin signaling pathway;Melanoma;Regulation of actin cytoskeleton;Hepatitis C;Non-small cell lung cancer;Measles;Insulin signaling pathway;Phosphatidylinositol signaling system;Carbohydrate digestion and absorption;Small cell lung cancer;Progesterone-mediated oocyte maturation;Aldosterone-regulated sodium reabsorption;Prostate cancer;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Type II diabetes mellitus;Colorectal cancer;Amoebiasis
5291,169,58,1,30,116,0,48,0,58,153,0,0,"PIK3CB;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta",GO:0005634//nucleus;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0006644//phospholipid metabolic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0010508//positive regulation of autophagy;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0001952//regulation of cell-matrix adhesion;GO:0007186//G-protein coupled receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0000187//activation of MAPK activity;GO:0030168//platelet activation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0016477//cell migration;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0046854//phosphatidylinositol phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007596//blood coagulation;GO:0006935//chemotaxis;GO:0006914//autophagy;GO:0045087//innate immune response;GO:0070527//platelet aggregation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0040016//embryonic cleavage;GO:2000369//regulation of clathrin-mediated endocytosis,"GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0043560//insulin receptor substrate binding;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity",K00922//Measles;Non-small cell lung cancer;Hepatitis C;Melanoma;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;Type II diabetes mellitus;Amoebiasis;Colorectal cancer;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Chronic myeloid leukemia;Aldosterone-regulated sodium reabsorption;Prostate cancer;Carbohydrate digestion and absorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;Phosphatidylinositol signaling system;Insulin signaling pathway;Glioma;Inositol phosphate metabolism;Focal adhesion;VEGF signaling pathway;Endometrial cancer;Toxoplasmosis;Osteoclast differentiation;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Bacterial invasion of epithelial cells;HTLV-I infection;Jak-STAT signaling pathway;ErbB signaling pathway;Epstein-Barr virus infection;Renal cell carcinoma;Apoptosis;mTOR signaling pathway;Toll-like receptor signaling pathway;Influenza A;Chemokine signaling pathway;Pathways in cancer;Pancreatic cancer
5292,0,0,0,0,0,17,0,0,18,4,27,0,"PIM1;Pim-1 proto-oncogene, serine/threonine kinase",GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0046777//protein autophosphorylation;GO:0030212//hyaluronan metabolic process;GO:0007049//cell cycle,GO:0030145//manganese ion binding;GO:0008134//transcription factor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0043024//ribosomal small subunit binding;GO:0005524//ATP binding,K04702//Jak-STAT signaling pathway;Acute myeloid leukemia
5293,12,0,1,44,0,10,18,118,19,0,56,0,"PIK3CD;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta",GO:0042629//mast cell granule;GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0005886//plasma membrane,GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0035747//natural killer cell chemotaxis;GO:0002551//mast cell chemotaxis;GO:0002679//respiratory burst involved in defense response;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0060374//mast cell differentiation;GO:0035754//B cell chemotaxis;GO:0001816//cytokine production;GO:0006661//phosphatidylinositol biosynthetic process;GO:0050852//T cell receptor signaling pathway;GO:0030101//natural killer cell activation;GO:0046854//phosphatidylinositol phosphorylation;GO:0010818//T cell chemotaxis;GO:0045087//innate immune response;GO:0042110//T cell activation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007165//signal transduction;GO:0072672//neutrophil extravasation;GO:0042113//B cell activation;GO:0006954//inflammatory response;GO:0006644//phospholipid metabolic process;GO:0001779//natural killer cell differentiation;GO:0006468//protein phosphorylation;GO:0001782//B cell homeostasis;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043303//mast cell degranulation;GO:0030217//T cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0030593//neutrophil chemotaxis;GO:0002250//adaptive immune response,"GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0005515//protein binding;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0005524//ATP binding;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity",K00922//Pathways in cancer;Chemokine signaling pathway;Pancreatic cancer;Toll-like receptor signaling pathway;Influenza A;Apoptosis;mTOR signaling pathway;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;Bacterial invasion of epithelial cells;HTLV-I infection;Jak-STAT signaling pathway;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Endometrial cancer;Toxoplasmosis;Osteoclast differentiation;Glioma;Focal adhesion;VEGF signaling pathway;Inositol phosphate metabolism;Phosphatidylinositol signaling system;Insulin signaling pathway;Prostate cancer;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Small cell lung cancer;Progesterone-mediated oocyte maturation;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Chronic myeloid leukemia;Type II diabetes mellitus;Colorectal cancer;Amoebiasis;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;B cell receptor signaling pathway;Non-small cell lung cancer;Regulation of actin cytoskeleton;Melanoma;Hepatitis C;Neurotrophin signaling pathway;Measles
5294,0,0,0,0,0,0,2,6,17,0,1,0,"PIK3CG;phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma","GO:0005886//plasma membrane;GO:0042629//mast cell granule;GO:0005829//cytosol;GO:0016020//membrane;GO:0005944//phosphatidylinositol 3-kinase complex, class IB;GO:0005737//cytoplasm",GO:0043303//mast cell degranulation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0006468//protein phosphorylation;GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response;GO:0072672//neutrophil extravasation;GO:0010897//negative regulation of triglyceride catabolic process;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0030593//neutrophil chemotaxis;GO:0002250//adaptive immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032252//secretory granule localization;GO:0044281//small molecule metabolic process;GO:0043406//positive regulation of MAP kinase activity;GO:0010818//T cell chemotaxis;GO:0006897//endocytosis;GO:0007596//blood coagulation;GO:0046854//phosphatidylinositol phosphorylation;GO:0001816//cytokine production;GO:0006661//phosphatidylinositol biosynthetic process;GO:0002679//respiratory burst involved in defense response;GO:0002407//dendritic cell chemotaxis;GO:0035747//natural killer cell chemotaxis;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0030168//platelet activation;GO:0097284//hepatocyte apoptotic process;GO:0002675//positive regulation of acute inflammatory response;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0042110//T cell activation;GO:0070527//platelet aggregation;GO:0042098//T cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045087//innate immune response;GO:0055118//negative regulation of cardiac muscle contraction;GO:0051897//positive regulation of protein kinase B signaling;GO:0001525//angiogenesis,"GO:0005524//ATP binding;GO:0035005//1-phosphatidylinositol-4-phosphate 3-kinase activity;GO:0046875//ephrin receptor binding;GO:0004672//protein kinase activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0046934//phosphatidylinositol-4,5-bisphosphate 3-kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity",K00922//Influenza A;Toll-like receptor signaling pathway;Chemokine signaling pathway;Pathways in cancer;Pancreatic cancer;ErbB signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;Apoptosis;mTOR signaling pathway;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Jak-STAT signaling pathway;Bacterial invasion of epithelial cells;HTLV-I infection;Glioma;Focal adhesion;Inositol phosphate metabolism;VEGF signaling pathway;Osteoclast differentiation;Toxoplasmosis;Endometrial cancer;Prostate cancer;Aldosterone-regulated sodium reabsorption;Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;Phosphatidylinositol signaling system;Insulin signaling pathway;Amoebiasis;Colorectal cancer;Type II diabetes mellitus;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chronic myeloid leukemia;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Acute myeloid leukemia;Cholinergic synapse;Fc epsilon RI signaling pathway;Measles;Non-small cell lung cancer;Melanoma;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Hepatitis C
5295,0,50,1,53,169,19,18,0,36,316,0,0,"PIK3R1;phosphoinositide-3-kinase, regulatory subunit 1 (alpha)","GO:0005886//plasma membrane;GO:0005942//phosphatidylinositol 3-kinase complex;GO:0016020//membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005943//phosphatidylinositol 3-kinase complex, class IA",GO:0006468//protein phosphorylation;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050900//leukocyte migration;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006644//phospholipid metabolic process;GO:0001953//negative regulation of cell-matrix adhesion;GO:0030183//B cell differentiation;GO:0030335//positive regulation of cell migration;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0034644//cellular response to UV;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0051531//NFAT protein import into nucleus;GO:0031295//T cell costimulation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0050852//T cell receptor signaling pathway;GO:0046854//phosphatidylinositol phosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0045671//negative regulation of osteoclast differentiation;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016032//viral process;GO:0043066//negative regulation of apoptotic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0046326//positive regulation of glucose import;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0060396//growth hormone receptor signaling pathway;GO:0045087//innate immune response,GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0043559//insulin binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0043560//insulin receptor substrate binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005159//insulin-like growth factor receptor binding;GO:0043125//ErbB-3 class receptor binding;GO:0005158//insulin receptor binding;GO:0019903//protein phosphatase binding,K02649//Progesterone-mediated oocyte maturation;Small cell lung cancer;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Prostate cancer;Insulin signaling pathway;Phosphatidylinositol signaling system;Colorectal cancer;Amoebiasis;Type II diabetes mellitus;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;B cell receptor signaling pathway;Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Measles;Melanoma;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Hepatitis C;Non-small cell lung cancer;Influenza A;Toll-like receptor signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Epstein-Barr virus infection;Renal cell carcinoma;ErbB signaling pathway;mTOR signaling pathway;Apoptosis;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Focal adhesion;VEGF signaling pathway;Glioma;Toxoplasmosis;Osteoclast differentiation;Endometrial cancer
5296,0,0,0,0,37,0,10,0,21,0,0,0,"PIK3R2;phosphoinositide-3-kinase, regulatory subunit 2 (beta)",GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex,GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006644//phospholipid metabolic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction,GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0030971//receptor tyrosine kinase binding;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0005515//protein binding,K02649//Carbohydrate digestion and absorption;Small cell lung cancer;Progesterone-mediated oocyte maturation;Aldosterone-regulated sodium reabsorption;Prostate cancer;Insulin signaling pathway;Phosphatidylinositol signaling system;Type II diabetes mellitus;Colorectal cancer;Amoebiasis;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;B cell receptor signaling pathway;Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;Chagas disease (American trypanosomiasis);Measles;Melanoma;Hepatitis C;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Non-small cell lung cancer;Toll-like receptor signaling pathway;Influenza A;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Epstein-Barr virus infection;Renal cell carcinoma;ErbB signaling pathway;mTOR signaling pathway;Apoptosis;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;HTLV-I infection;Bacterial invasion of epithelial cells;Jak-STAT signaling pathway;Focal adhesion;VEGF signaling pathway;Glioma;Endometrial cancer;Toxoplasmosis;Osteoclast differentiation
5297,1,2,0,2,85,13,18,7,42,0,60,406,"PI4KA;phosphatidylinositol 4-kinase, catalytic, alpha",GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030660//Golgi-associated vesicle membrane,GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006644//phospholipid metabolic process,GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding,K00888//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism
5298,0,26,0,10,67,32,0,0,41,0,0,0,"PI4KB;phosphatidylinositol 4-kinase, catalytic, beta",GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0005741//mitochondrial outer membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0048015//phosphatidylinositol-mediated signaling;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0006898//receptor-mediated endocytosis;GO:0006644//phospholipid metabolic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004430//1-phosphatidylinositol 4-kinase activity,K00888//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
5300,33,0,1,0,2,0,0,0,13,42,0,0,"PIN1;peptidylprolyl cis/trans isomerase, NIMA-interacting 1",GO:0016607//nuclear speck;GO:0030496//midbody;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032321//positive regulation of Rho GTPase activity;GO:0045087//innate immune response;GO:0000413//protein peptidyl-prolyl isomerization;GO:2000146//negative regulation of cell motility;GO:0032480//negative regulation of type I interferon production;GO:0007088//regulation of mitosis;GO:0007049//cell cycle;GO:0032465//regulation of cytokinesis;GO:0006457//protein folding;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0001934//positive regulation of protein phosphorylation,GO:0031434//mitogen-activated protein kinase kinase binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0050815//phosphoserine binding;GO:0050816//phosphothreonine binding;GO:0005515//protein binding;GO:0032794//GTPase activating protein binding,K09578//RIG-I-like receptor signaling pathway
5301,0,0,0,0,0,0,0,0,9,0,0,322,"PIN1P1;peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1",-,-,-,K09578//RIG-I-like receptor signaling pathway
5303,0,0,0,0,53,28,0,0,0,0,0,0,"PIN4;protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0030684//preribosome;GO:0005819//spindle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,GO:0000413//protein peptidyl-prolyl isomerization;GO:0006364//rRNA processing;GO:0006457//protein folding,GO:0003677//DNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0044822//poly(A) RNA binding;GO:0003681//bent DNA binding;GO:0003690//double-stranded DNA binding,-
5304,0,0,0,6,0,0,0,0,1,0,1,0,PIP;prolactin-induced protein,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0016324//apical plasma membrane,GO:0001895//retina homeostasis;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0002682//regulation of immune system process;GO:0070233//negative regulation of T cell apoptotic process;GO:0006508//proteolysis;GO:0010628//positive regulation of gene expression,GO:0005515//protein binding;GO:0019864//IgG binding;GO:0003779//actin binding;GO:0046983//protein dimerization activity;GO:0004190//aspartic-type endopeptidase activity;GO:0001948//glycoprotein binding,-
5305,1,0,0,4,47,35,0,107,39,0,3,0,"PIP4K2A;phosphatidylinositol-5-phosphate 4-kinase, type II, alpha",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0035855//megakaryocyte development,GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0005524//ATP binding;GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity,K00920//Inositol phosphate metabolism;Metabolic pathways;Regulation of actin cytoskeleton;Endocytosis;Phosphatidylinositol signaling system
5306,0,10,2,33,104,0,0,0,19,0,0,0,"PITPNA;phosphatidylinositol transfer protein, alpha",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0015914//phospholipid transport;GO:0007601//visual perception;GO:0007411//axon guidance;GO:0006629//lipid metabolic process,GO:0008289//lipid binding;GO:0008525//phosphatidylcholine transporter activity;GO:0008526//phosphatidylinositol transporter activity,K01106//Phosphatidylinositol signaling system;Metabolic pathways;Insulin signaling pathway;Inositol phosphate metabolism
5307,0,0,0,0,1,7,18,0,13,0,0,0,PITX1;paired-like homeodomain 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0014707//branchiomeric skeletal muscle development;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0001501//skeletal system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035116//embryonic hindlimb morphogenesis;GO:0048625//myoblast fate commitment;GO:0051216//cartilage development;GO:0021983//pituitary gland development",GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
5308,0,0,0,0,8,0,16,0,0,0,0,0,PITX2;paired-like homeodomain 2,GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:2000288//positive regulation of myoblast proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0035315//hair cell differentiation;GO:0061325//cell proliferation involved in outflow tract morphogenesis;GO:0048557//embryonic digestive tract morphogenesis;GO:0001570//vasculogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0060460//left lung morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0031076//embryonic camera-type eye development;GO:0060577//pulmonary vein morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042476//odontogenesis;GO:0035993//deltoid tuberosity development;GO:0009725//response to hormone;GO:0060578//superior vena cava morphogenesis;GO:0055015//ventricular cardiac muscle cell development;GO:0043388//positive regulation of DNA binding;GO:0008585//female gonad development;GO:0021763//subthalamic nucleus development;GO:0035116//embryonic hindlimb morphogenesis;GO:0048536//spleen development;GO:0043010//camera-type eye development;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0061072//iris morphogenesis;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0021855//hypothalamus cell migration;GO:0007520//myoblast fusion;GO:0001764//neuron migration;GO:0060126//somatotropin secreting cell differentiation;GO:0061031//endodermal digestive tract morphogenesis;GO:0070986//left/right axis specification;GO:0008584//male gonad development;GO:0003350//pulmonary myocardium development;GO:0060412//ventricular septum morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0060127//prolactin secreting cell differentiation;GO:0003171//atrioventricular valve development;GO:0030334//regulation of cell migration;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007368//determination of left/right symmetry;GO:0035886//vascular smooth muscle cell differentiation;GO:0033189//response to vitamin A;GO:0016055//Wnt signaling pathway;GO:0002074//extraocular skeletal muscle development;GO:0001569//patterning of blood vessels",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0051219//phosphoprotein binding;GO:0043021//ribonucleoprotein complex binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0031490//chromatin DNA binding;GO:0001085//RNA polymerase II transcription factor binding,K04686//TGF-beta signaling pathway
5310,0,30,86,0,55,23,18,117,259,0,7,74,PKD1;polycystic kidney disease 1 (autosomal dominant),GO:0002133//polycystin complex;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0031512//motile primary cilium;GO:0005737//cytoplasm;GO:0016328//lateral plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005929//cilium;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane,GO:0001822//kidney development;GO:0048565//digestive tract development;GO:0007507//heart development;GO:0001889//liver development;GO:0051216//cartilage development;GO:0021510//spinal cord development;GO:0072205//metanephric collecting duct development;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0048754//branching morphogenesis of an epithelial tube;GO:0043588//skin development;GO:0032092//positive regulation of protein binding;GO:0007259//JAK-STAT cascade;GO:0001892//embryonic placenta development;GO:0007161//calcium-independent cell-matrix adhesion;GO:0007050//cell cycle arrest;GO:0072218//metanephric ascending thin limb development;GO:0061136//regulation of proteasomal protein catabolic process;GO:0006807//nitrogen compound metabolic process;GO:0060236//regulation of mitotic spindle organization;GO:0072287//metanephric distal tubule morphogenesis;GO:0070588//calcium ion transmembrane transport;GO:0001502//cartilage condensation;GO:0072164//mesonephric tubule development;GO:0006611//protein export from nucleus;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001701//in utero embryonic development;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0060428//lung epithelium development;GO:0007218//neuropeptide signaling pathway;GO:0034405//response to fluid shear stress;GO:0009653//anatomical structure morphogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0050982//detection of mechanical stimulus;GO:0072237//metanephric proximal tubule development;GO:0021915//neural tube development;GO:0072177//mesonephric duct development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048806//genitalia development;GO:0060674//placenta blood vessel development;GO:0007160//cell-matrix adhesion,GO:0019904//protein domain specific binding;GO:0005261//cation channel activity;GO:0044325//ion channel binding;GO:0019901//protein kinase binding;GO:0030246//carbohydrate binding;GO:0005262//calcium channel activity;GO:0005515//protein binding,-
5311,0,0,0,0,18,13,0,0,63,0,0,0,PKD2;polycystic kidney disease 2 (autosomal dominant),GO:0031512//motile primary cilium;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0002133//polycystin complex;GO:0072686//mitotic spindle;GO:0070062//extracellular vesicular exosome;GO:0036064//ciliary basal body;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0045180//basal cortex;GO:0005929//cilium;GO:0031513//nonmotile primary cilium;GO:0030027//lamellipodium;GO:0060170//ciliary membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0031941//filamentous actin,"GO:0001889//liver development;GO:0007507//heart development;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0071498//cellular response to fluid shear stress;GO:0021510//spinal cord development;GO:0071158//positive regulation of cell cycle arrest;GO:0006816//calcium ion transport;GO:0008285//negative regulation of cell proliferation;GO:0071470//cellular response to osmotic stress;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0051209//release of sequestered calcium ion into cytosol;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0003127//detection of nodal flow;GO:0001892//embryonic placenta development;GO:0007368//determination of left/right symmetry;GO:0007050//cell cycle arrest;GO:0007259//JAK-STAT cascade;GO:0042127//regulation of cell proliferation;GO:0072218//metanephric ascending thin limb development;GO:0090279//regulation of calcium ion import;GO:0071910//determination of liver left/right asymmetry;GO:0072235//metanephric distal tubule development;GO:0071464//cellular response to hydrostatic pressure;GO:0070588//calcium ion transmembrane transport;GO:0035502//metanephric part of ureteric bud development;GO:0035904//aorta development;GO:0072164//mesonephric tubule development;GO:0072219//metanephric cortical collecting duct development;GO:0034614//cellular response to reactive oxygen species;GO:0030814//regulation of cAMP metabolic process;GO:0072075//metanephric mesenchyme development;GO:0061441//renal artery morphogenesis;GO:0072214//metanephric cortex development;GO:0071805//potassium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0001947//heart looping;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0050982//detection of mechanical stimulus;GO:0051298//centrosome duplication;GO:0021915//neural tube development;GO:0072177//mesonephric duct development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061333//renal tubule morphogenesis;GO:0072284//metanephric S-shaped body morphogenesis;GO:0072208//metanephric smooth muscle tissue development;GO:0060674//placenta blood vessel development",GO:0005509//calcium ion binding;GO:0051219//phosphoprotein binding;GO:0005245//voltage-gated calcium channel activity;GO:0044325//ion channel binding;GO:0042803//protein homodimerization activity;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity;GO:0008092//cytoskeletal protein binding;GO:0005102//receptor binding;GO:0042805//actinin binding;GO:0005515//protein binding;GO:0048763//calcium-induced calcium release activity;GO:0051371//muscle alpha-actinin binding;GO:0043398//HLH domain binding;GO:0005248//voltage-gated sodium channel activity;GO:0051117//ATPase binding;GO:0042802//identical protein binding;GO:0022843//voltage-gated cation channel activity,-
5313,0,0,0,0,0,8,0,0,61,0,0,0,"PKLR;pyruvate kinase, liver and RBC",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0031325//positive regulation of cellular metabolic process;GO:0032869//cellular response to insulin stimulus;GO:0009408//response to heat;GO:0009749//response to glucose;GO:0010226//response to lithium ion;GO:0051707//response to other organism;GO:0044281//small molecule metabolic process;GO:0033198//response to ATP;GO:0007584//response to nutrient;GO:0001666//response to hypoxia;GO:0006112//energy reserve metabolic process;GO:0042866//pyruvate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0031018//endocrine pancreas development;GO:0051591//response to cAMP;GO:0006754//ATP biosynthetic process;GO:0016310//phosphorylation;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004743//pyruvate kinase activity;GO:0030955//potassium ion binding,K12406//Purine metabolism;Type II diabetes mellitus;Maturity onset diabetes of the young;Glycolysis / Gluconeogenesis;Metabolic pathways;Insulin signaling pathway;Pyruvate metabolism
5314,2,0,0,0,0,96,32,0,122,0,8,0,PKHD1;polycystic kidney and hepatic disease 1 (autosomal recessive),GO:0072372//primary cilium;GO:0031362//anchored component of external side of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0036064//ciliary basal body;GO:0070062//extracellular vesicular exosome;GO:0072686//mitotic spindle;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005813//centrosome,GO:0051271//negative regulation of cellular component movement;GO:0042592//homeostatic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0001822//kidney development;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0008284//positive regulation of cell proliferation;GO:0006874//cellular calcium ion homeostasis;GO:0051898//negative regulation of protein kinase B signaling;GO:0010824//regulation of centrosome duplication;GO:0032006//regulation of TOR signaling;GO:0042384//cilium assembly;GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion,GO:0004872//receptor activity;GO:0005515//protein binding,-
5315,0,138,4,79,283,16,1,28,31,1,1,0,"PKM;pyruvate kinase, muscle",GO:0005829//cytosol;GO:0005929//cilium;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0031982//vesicle,GO:0006006//glucose metabolic process;GO:0006096//glycolytic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0012501//programmed cell death;GO:0016310//phosphorylation,GO:0004743//pyruvate kinase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0030955//potassium ion binding;GO:0023026//MHC class II protein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K00873//Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Metabolic pathways;Thiamine metabolism;Pyruvate metabolism;Type II diabetes mellitus;Purine metabolism
5316,0,0,0,9,15,0,40,0,40,0,9,5,PKNOX1;PBX/knotted 1 homeobox 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex,GO:0006366//transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043010//camera-type eye development;GO:0001525//angiogenesis;GO:0030217//T cell differentiation,GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,K15613//Transcriptional misregulation in cancer
5317,0,77,3,24,197,9,26,70,24,163,1,278,PKP1;plakophilin 1,GO:0030057//desmosome;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,GO:0006915//apoptotic process;GO:0045110//intermediate filament bundle assembly;GO:0016337//single organismal cell-cell adhesion;GO:0007165//signal transduction;GO:0007275//multicellular organismal development;GO:0007155//cell adhesion;GO:0006921//cellular component disassembly involved in execution phase of apoptosis,GO:0005515//protein binding;GO:0030280//structural constituent of epidermis;GO:0004871//signal transducer activity;GO:0005521//lamin binding;GO:0019215//intermediate filament binding,-
5318,0,45,0,0,52,40,0,2,23,0,0,0,PKP2;plakophilin 2,GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0014704//intercalated disc;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005882//intermediate filament;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0030057//desmosome;GO:0005730//nucleolus,GO:0034334//adherens junction maintenance;GO:0086091//regulation of heart rate by cardiac conduction;GO:0016264//gap junction assembly;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:2000810//regulation of tight junction assembly;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0086001//cardiac muscle cell action potential;GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0016337//single organismal cell-cell adhesion;GO:0045110//intermediate filament bundle assembly;GO:0048496//maintenance of organ identity;GO:0010765//positive regulation of sodium ion transport;GO:0055088//lipid homeostasis;GO:0086019//cell-cell signaling involved in cardiac conduction;GO:0007507//heart development;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0002159//desmosome assembly,GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0017080//sodium channel regulator activity;GO:0044325//ion channel binding;GO:0032947//protein complex scaffold;GO:0019215//intermediate filament binding,K12642//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
5320,0,36,0,1,0,0,0,0,29,0,0,0,"PLA2G2A;phospholipase A2, group IIA (platelets, synovial fluid)",GO:0005739//mitochondrion;GO:0030141//secretory granule;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005789//endoplasmic reticulum membrane,GO:0016042//lipid catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0050729//positive regulation of inflammatory response;GO:0035019//somatic stem cell maintenance;GO:0050680//negative regulation of epithelial cell proliferation;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0036149//phosphatidylinositol acyl-chain remodeling,GO:0005543//phospholipid binding;GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity;GO:0047498//calcium-dependent phospholipase A2 activity,K01047//Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism;Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Metabolic pathways;Vascular smooth muscle contraction;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse
5321,0,0,0,0,0,0,2,0,13,46,0,0,"PLA2G4A;phospholipase A2, group IVA (cytosolic, calcium-dependent)",GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005743//mitochondrial inner membrane;GO:0005794//Golgi apparatus;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005829//cytosol,GO:0006644//phospholipid metabolic process;GO:0042127//regulation of cell proliferation;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046456//icosanoid biosynthetic process;GO:0050482//arachidonic acid secretion;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0030168//platelet activation;GO:0035965//cardiolipin acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0019369//arachidonic acid metabolic process;GO:0007596//blood coagulation;GO:0006654//phosphatidic acid biosynthetic process;GO:0071236//cellular response to antibiotic;GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0006663//platelet activating factor biosynthetic process;GO:0009395//phospholipid catabolic process,GO:0004622//lysophospholipase activity;GO:0005544//calcium-dependent phospholipid binding;GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding;GO:0047498//calcium-dependent phospholipase A2 activity,K01047//Vascular smooth muscle contraction;Metabolic pathways;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism;Fc epsilon RI signaling pathway;Long-term depression;Fc gamma R-mediated phagocytosis
5322,0,0,0,0,0,0,0,68,8,0,0,0,"PLA2G5;phospholipase A2, group V",GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0050482//arachidonic acid secretion;GO:0044281//small molecule metabolic process;GO:0019370//leukotriene biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0051591//response to cAMP;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0006663//platelet activating factor biosynthetic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0034097//response to cytokine,GO:0008201//heparin binding;GO:0047498//calcium-dependent phospholipase A2 activity;GO:0005509//calcium ion binding,K01047//Ether lipid metabolism;VEGF signaling pathway;Glycerophospholipid metabolism;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway;Vascular smooth muscle contraction;Metabolic pathways;Glutamatergic synapse;MAPK signaling pathway;Linoleic acid metabolism;alpha-Linolenic acid metabolism;Serotonergic synapse;Pancreatic secretion;GnRH signaling pathway
5324,0,0,0,0,0,17,51,0,106,0,0,0,PLAG1;pleiomorphic adenoma gene 1,GO:0005634//nucleus,GO:0060736//prostate gland growth;GO:0035264//multicellular organism growth;GO:0060252//positive regulation of glial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0022612//gland morphogenesis;GO:0035265//organ growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010629//negative regulation of gene expression,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
5325,1,0,0,0,22,44,0,37,20,33,0,0,PLAGL1;pleiomorphic adenoma gene-like 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0007050//cell cycle arrest;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035914//skeletal muscle cell differentiation;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding,-
5326,5,0,1,9,21,27,0,54,12,0,0,0,PLAGL2;pleiomorphic adenoma gene-like 2,GO:0005634//nucleus,"GO:0009791//post-embryonic development;GO:0006629//lipid metabolic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0034378//chylomicron assembly",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
5327,0,44,0,3,0,18,0,0,20,4,7,0,"PLAT;plasminogen activator, tissue",GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0031012//extracellular matrix;GO:0045202//synapse;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0045177//apical part of cell,"GO:0051384//response to glucocorticoid;GO:0031639//plasminogen activation;GO:0006464//cellular protein modification process;GO:0051591//response to cAMP;GO:0045861//negative regulation of proteolysis;GO:0043434//response to peptide hormone;GO:0006508//proteolysis;GO:0048167//regulation of synaptic plasticity;GO:0007596//blood coagulation;GO:0014909//smooth muscle cell migration;GO:0001666//response to hypoxia;GO:0060279//positive regulation of ovulation;GO:0035249//synaptic transmission, glutamatergic;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0042730//fibrinolysis",GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity,K01343//Transcriptional misregulation in cancer;Complement and coagulation cascades
5328,5,0,39,0,0,0,0,0,17,150,0,0,"PLAU;plasminogen activator, urokinase",GO:0005925//focal adhesion;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0009986//cell surface,GO:0006508//proteolysis;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0006935//chemotaxis;GO:0014909//smooth muscle cell migration;GO:0007596//blood coagulation;GO:0042730//fibrinolysis;GO:0001666//response to hypoxia;GO:0061041//regulation of wound healing;GO:2000097//regulation of smooth muscle cell-matrix adhesion;GO:0010469//regulation of receptor activity;GO:0007165//signal transduction;GO:0042127//regulation of cell proliferation;GO:0014910//regulation of smooth muscle cell migration,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K01348//Complement and coagulation cascades;Transcriptional misregulation in cancer;NF-kappa B signaling pathway
533,0,0,0,0,1,1,0,0,58,0,0,0,"ATP6V0B;ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b","GO:0016021//integral component of membrane;GO:0005774//vacuolar membrane;GO:0010008//endosome membrane;GO:0030670//phagocytic vesicle membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain",GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0051701//interaction with host;GO:0055085//transmembrane transport;GO:0008286//insulin receptor signaling pathway;GO:0015992//proton transport,GO:0005215//transporter activity;GO:0015078//hydrogen ion transmembrane transporter activity,K03661//Metabolic pathways;Oxidative phosphorylation;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Lysosome;Phagosome;Rheumatoid arthritis;Synaptic vesicle cycle;Tuberculosis
5330,162,8,0,0,0,19,5,0,64,0,10,0,"PLCB2;phospholipase C, beta 2",GO:0005829//cytosol,GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0007268//synaptic transmission;GO:0035556//intracellular signal transduction;GO:0007202//activation of phospholipase C activity;GO:0006644//phospholipid metabolic process;GO:0050913//sensory perception of bitter taste;GO:0044281//small molecule metabolic process,GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004629//phospholipase C activity,K05858//Salivary secretion;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Cholinergic synapse;Long-term depression;Chagas disease (American trypanosomiasis);Melanogenesis;Inositol phosphate metabolism;Gastric acid secretion;Alzheimer's disease;Long-term potentiation;Carbohydrate digestion and absorption;Serotonergic synapse;African trypanosomiasis;Pancreatic secretion;Huntington's disease;Phosphatidylinositol signaling system;GnRH signaling pathway;Chemokine signaling pathway;Dopaminergic synapse;Gap junction;Amoebiasis;Phototransduction - fly;Metabolic pathways;Vascular smooth muscle contraction;Wnt signaling pathway;Glutamatergic synapse;Taste transduction
5331,0,0,0,0,0,11,55,44,26,0,0,0,"PLCB3;phospholipase C, beta 3 (phosphatidylinositol-specific)",GO:0043234//protein complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane;GO:0005730//nucleolus,GO:0007268//synaptic transmission;GO:0003073//regulation of systemic arterial blood pressure;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process;GO:0016042//lipid catabolic process;GO:0035556//intracellular signal transduction,GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005516//calmodulin binding;GO:0004629//phospholipase C activity,K05858//Alzheimer's disease;Inositol phosphate metabolism;Melanogenesis;Gastric acid secretion;Long-term depression;Cholinergic synapse;Chagas disease (American trypanosomiasis);Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Retrograde endocannabinoid signaling;Calcium signaling pathway;Vascular smooth muscle contraction;Metabolic pathways;Wnt signaling pathway;Glutamatergic synapse;Taste transduction;Amoebiasis;Phototransduction - fly;Huntington's disease;Gap junction;Dopaminergic synapse;Chemokine signaling pathway;Phosphatidylinositol signaling system;GnRH signaling pathway;Long-term potentiation;Carbohydrate digestion and absorption;Pancreatic secretion;African trypanosomiasis;Serotonergic synapse
5332,111,0,1,2,40,41,6,1,33,0,0,0,"PLCB4;phospholipase C, beta 4",GO:0005829//cytosol;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0005790//smooth endoplasmic reticulum;GO:0005634//nucleus,GO:0035556//intracellular signal transduction;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process,GO:0004629//phospholipase C activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity,K05858//Amoebiasis;Phototransduction - fly;Vascular smooth muscle contraction;Wnt signaling pathway;Metabolic pathways;Glutamatergic synapse;Taste transduction;Carbohydrate digestion and absorption;Long-term potentiation;Serotonergic synapse;African trypanosomiasis;Pancreatic secretion;Huntington's disease;Phosphatidylinositol signaling system;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Dopaminergic synapse;Melanogenesis;Inositol phosphate metabolism;Gastric acid secretion;Alzheimer's disease;Salivary secretion;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Cholinergic synapse;Long-term depression;Chagas disease (American trypanosomiasis)
5333,0,28,0,1,0,0,39,0,4,0,12,0,"PLCD1;phospholipase C, delta 1",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0060716//labyrinthine layer blood vessel development;GO:0035556//intracellular signal transduction;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0042127//regulation of cell proliferation;GO:0006644//phospholipid metabolic process;GO:0001525//angiogenesis;GO:0044281//small molecule metabolic process,GO:0070300//phosphatidic acid binding;GO:0032794//GTPase activating protein binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:1901981//phosphatidylinositol phosphate binding;GO:0001786//phosphatidylserine binding,K05857//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Calcium signaling pathway
53335,15,0,0,0,0,0,5,0,44,32,0,0,BCL11A;B-cell CLL/lymphoma 11A (zinc finger protein),GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016604//nuclear body,"GO:0030217//T cell differentiation;GO:0010977//negative regulation of neuron projection development;GO:2000171//negative regulation of dendrite development;GO:0010976//positive regulation of neuron projection development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030517//negative regulation of axon extension;GO:0030183//B cell differentiation;GO:0048672//positive regulation of collateral sprouting;GO:0050773//regulation of dendrite development;GO:0032463//negative regulation of protein homooligomerization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048671//negative regulation of collateral sprouting;GO:0006351//transcription, DNA-templated;GO:0016925//protein sumoylation",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding,-
53339,0,30,0,52,124,8,0,0,14,0,0,0,BTBD1;BTB (POZ) domain containing 1,GO:0000932//cytoplasmic mRNA processing body;GO:0043234//protein complex,GO:0043393//regulation of protein binding;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
5334,0,0,0,8,13,28,0,41,57,0,0,29,PLCL1;phospholipase C-like 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm,"GO:0006629//lipid metabolic process;GO:0032228//regulation of synaptic transmission, GABAergic;GO:1900122//positive regulation of receptor binding;GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0035556//intracellular signal transduction;GO:0007214//gamma-aminobutyric acid signaling pathway","GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0050811//GABA receptor binding;GO:0004629//phospholipase C activity",K15375//GABAergic synapse
53340,0,0,0,4,10,23,0,0,0,0,0,0,SPA17;sperm autoantigenic protein 17,GO:0005737//cytoplasm;GO:0031514//motile cilium;GO:0072372//primary cilium;GO:0016020//membrane,GO:0007339//binding of sperm to zona pellucida;GO:0007338//single fertilization;GO:0003351//epithelial cilium movement;GO:0007283//spermatogenesis,-,K04739//Apoptosis;Insulin signaling pathway
53342,0,20,0,0,16,0,0,0,14,0,4,0,IL17D;interleukin 17D,GO:0005615//extracellular space,GO:0006954//inflammatory response,GO:0005125//cytokine activity,-
53343,0,1,0,0,30,1,0,0,23,0,0,0,NUDT9;nudix (nucleoside diphosphate linked moiety X)-type motif 9,GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0046032//ADP catabolic process;GO:0046709//IDP catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0044281//small molecule metabolic process,GO:0047631//ADP-ribose diphosphatase activity;GO:0019144//ADP-sugar diphosphatase activity;GO:0043262//adenosine-diphosphatase activity,K13988//Purine metabolism
53345,0,0,0,0,15,22,0,0,0,0,0,0,TM6SF2;transmembrane 6 superfamily member 2,GO:0016021//integral component of membrane,-,-,-
53346,0,29,35,63,90,0,14,0,12,0,53,0,TM6SF1;transmembrane 6 superfamily member 1,GO:0016021//integral component of membrane,-,-,-
53347,0,0,0,0,0,0,0,0,56,0,9,0,UBASH3A;ubiquitin associated and SH3 domain containing A,GO:0005634//nucleus;GO:0005829//cytosol,GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0008152//metabolic process;GO:0001817//regulation of cytokine production,GO:0003824//catalytic activity,-
53349,0,0,0,0,28,0,0,0,12,0,0,0,"ZFYVE1;zinc finger, FYVE domain containing 1",GO:0005795//Golgi stack;GO:0000407//pre-autophagosomal structure;GO:0005783//endoplasmic reticulum;GO:0005776//autophagic vacuole;GO:0048471//perinuclear region of cytoplasm,GO:0010923//negative regulation of phosphatase activity,"GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005545//1-phosphatidylinositol binding;GO:0008270//zinc ion binding;GO:0005515//protein binding",K12482//Endocytosis
5335,156,0,1,0,1,33,2,61,27,0,4,0,"PLCG1;phospholipase C, gamma 1",GO:0005886//plasma membrane;GO:0001726//ruffle;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0042995//cell projection,GO:0045087//innate immune response;GO:0001701//in utero embryonic development;GO:0045766//positive regulation of angiogenesis;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0000186//activation of MAPKK activity;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0007202//activation of phospholipase C activity;GO:0009395//phospholipid catabolic process;GO:0007411//axon guidance;GO:0016032//viral process;GO:0016477//cell migration;GO:0019722//calcium-mediated signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0010634//positive regulation of epithelial cell migration;GO:0007596//blood coagulation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0050852//T cell receptor signaling pathway;GO:0043647//inositol phosphate metabolic process,GO:0005509//calcium ion binding;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0035254//glutamate receptor binding;GO:0004629//phospholipase C activity;GO:0019901//protein kinase binding;GO:0005057//receptor signaling protein activity;GO:0030971//receptor tyrosine kinase binding,K01116//Calcium signaling pathway;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Fc epsilon RI signaling pathway;Glioma;Vibrio cholerae infection;Inositol phosphate metabolism;VEGF signaling pathway;Non-small cell lung cancer;Neurotrophin signaling pathway;Phosphatidylinositol signaling system;Pathways in cancer;NF-kappa B signaling pathway;ErbB signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Metabolic pathways
53353,110,0,0,0,0,33,63,1,157,0,15,0,LRP1B;low density lipoprotein receptor-related protein 1B,GO:0016021//integral component of membrane;GO:0043235//receptor complex,GO:0006898//receptor-mediated endocytosis;GO:0015031//protein transport,GO:0005509//calcium ion binding;GO:0005041//low-density lipoprotein receptor activity,K04550//Malaria;Alzheimer's disease
53354,0,22,0,16,35,29,17,0,73,0,0,0,PANK1;pantothenate kinase 1,GO:0005634//nucleus;GO:0071944//cell periphery;GO:0055037//recycling endosome;GO:0005829//cytosol;GO:0030118//clathrin coat,GO:0006766//vitamin metabolic process;GO:0016310//phosphorylation;GO:0015937//coenzyme A biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0015939//pantothenate metabolic process,GO:0005524//ATP binding;GO:0004594//pantothenate kinase activity,K09680//Pantothenate and CoA biosynthesis;Metabolic pathways
53358,0,0,0,0,0,11,19,0,26,0,8,0,SHC3;SHC (Src homology 2 domain containing) transforming protein 3,GO:0005829//cytosol,"GO:0035249//synaptic transmission, glutamatergic;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007417//central nervous system development;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0007611//learning or memory",GO:0005515//protein binding;GO:0004871//signal transducer activity,K06279//VEGF signaling pathway;Focal adhesion;Glioma;ErbB signaling pathway;Neurotrophin signaling pathway;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;Alcoholism;Insulin signaling pathway;Bacterial invasion of epithelial cells;Chemokine signaling pathway
5336,63,0,0,0,0,43,4,151,59,49,8,0,"PLCG2;phospholipase C, gamma 2 (phosphatidylinositol-specific)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0050853//B cell receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0030168//platelet activation;GO:0016055//Wnt signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0019722//calcium-mediated signaling;GO:0030183//B cell differentiation;GO:0045087//innate immune response;GO:0050852//T cell receptor signaling pathway;GO:0043647//inositol phosphate metabolic process;GO:0009395//phospholipid catabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007596//blood coagulation;GO:0051209//release of sequestered calcium ion into cytosol,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0004629//phospholipase C activity,K05859//ErbB signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;Natural killer cell mediated cytotoxicity;Metabolic pathways;Pathways in cancer;Phosphatidylinositol signaling system;NF-kappa B signaling pathway;Glioma;Vibrio cholerae infection;VEGF signaling pathway;Inositol phosphate metabolism;Osteoclast differentiation;Non-small cell lung cancer;Neurotrophin signaling pathway;Calcium signaling pathway;Fc gamma R-mediated phagocytosis;B cell receptor signaling pathway;Leukocyte transendothelial migration;Fc epsilon RI signaling pathway
5337,0,0,0,0,8,2,91,0,55,362,9,0,"PLD1;phospholipase D1, phosphatidylcholine-specific",GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane,GO:0006655//phosphatidylglycerol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007265//Ras protein signal transduction;GO:0006644//phospholipid metabolic process;GO:0050830//defense response to Gram-positive bacterium;GO:0007264//small GTPase mediated signal transduction;GO:0046474//glycerophospholipid biosynthetic process;GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006935//chemotaxis,GO:0005515//protein binding;GO:0004630//phospholipase D activity;GO:0035091//phosphatidylinositol binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity,K01115//Fc gamma R-mediated phagocytosis;Endocytosis;Pancreatic cancer;GnRH signaling pathway;Pathways in cancer;Ether lipid metabolism;Glycerophospholipid metabolism;Metabolic pathways;Glutamatergic synapse
53371,0,0,0,34,4,0,18,0,0,0,0,0,NUP54;nucleoporin 54kDa,GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005643//nuclear pore,GO:0051028//mRNA transport;GO:0006913//nucleocytoplasmic transport;GO:0010827//regulation of glucose transport;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0006605//protein targeting;GO:0019221//cytokine-mediated signaling pathway;GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle,GO:0005487//nucleocytoplasmic transporter activity,K14308//RNA transport
5338,0,0,0,1,17,0,65,0,17,0,0,0,PLD2;phospholipase D2,GO:0005886//plasma membrane;GO:0031526//brush border membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007010//cytoskeleton organization;GO:0016042//lipid catabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006644//phospholipid metabolic process;GO:0002031//G-protein coupled receptor internalization;GO:0045087//innate immune response;GO:0046474//glycerophospholipid biosynthetic process,GO:0035091//phosphatidylinositol binding;GO:0004630//phospholipase D activity;GO:0005515//protein binding;GO:0070290//N-acylphosphatidylethanolamine-specific phospholipase D activity,K01115//Pancreatic cancer;Endocytosis;Pathways in cancer;GnRH signaling pathway;Fc gamma R-mediated phagocytosis;Metabolic pathways;Glutamatergic synapse;Ether lipid metabolism;Glycerophospholipid metabolism
5339,235,0,0,0,7,54,70,72,94,0,12,0,PLEC;plectin,GO:0045111//intermediate filament cytoskeleton;GO:0042383//sarcolemma;GO:0005925//focal adhesion;GO:0030056//hemidesmosome;GO:0016528//sarcoplasm;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0043034//costamere,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0034329//cell junction assembly;GO:0030198//extracellular matrix organization;GO:0031581//hemidesmosome assembly;GO:0006915//apoptotic process,GO:0008307//structural constituent of muscle;GO:0003779//actin binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030506//ankyrin binding,-
5340,93,0,0,0,0,14,2,0,61,137,1,0,PLG;plasminogen,GO:0009986//cell surface;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031232//extrinsic component of external side of plasma membrane;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen,GO:0022617//extracellular matrix disassembly;GO:0048771//tissue remodeling;GO:0030198//extracellular matrix organization;GO:2000048//negative regulation of cell-cell adhesion mediated by cadherin;GO:0051918//negative regulation of fibrinolysis;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0042730//fibrinolysis;GO:0051919//positive regulation of fibrinolysis;GO:0044267//cellular protein metabolic process;GO:0002576//platelet degranulation;GO:0010812//negative regulation of cell-substrate adhesion;GO:0008285//negative regulation of cell proliferation;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity;GO:0034185//apolipoprotein binding;GO:0019904//protein domain specific binding,K01315//Staphylococcus aureus infection;Influenza A;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
53405,0,40,0,0,0,41,0,0,70,0,22,0,CLIC5;chloride intracellular channel 5,GO:0032420//stereocilium;GO:0005938//cell cortex;GO:0005815//microtubule organizing center;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0015629//actin cytoskeleton;GO:0034707//chloride channel complex,GO:0006821//chloride transport;GO:0007565//female pregnancy;GO:0007605//sensory perception of sound;GO:0002024//diet induced thermogenesis;GO:1902476//chloride transmembrane transport;GO:0044070//regulation of anion transport;GO:0050885//neuromuscular process controlling balance;GO:0060088//auditory receptor cell stereocilium organization;GO:0034765//regulation of ion transmembrane transport;GO:0008104//protein localization;GO:0006810//transport,GO:0005515//protein binding;GO:0005247//voltage-gated chloride channel activity,-
53407,0,0,0,12,46,0,58,48,47,0,0,0,STX18;syntaxin 18,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport,GO:0019904//protein domain specific binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding,K08492//SNARE interactions in vesicular transport;Phagosome
5341,0,0,0,0,0,0,0,0,33,0,11,0,PLEK;pleckstrin,GO:0005576//extracellular region;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0031529//ruffle organization;GO:0002244//hematopoietic progenitor cell differentiation;GO:0010572//positive regulation of platelet activation;GO:0070527//platelet aggregation;GO:0033625//positive regulation of integrin activation;GO:0031532//actin cytoskeleton reorganization;GO:0032233//positive regulation of actin filament bundle assembly;GO:0070528//protein kinase C signaling;GO:0006904//vesicle docking involved in exocytosis;GO:0070560//protein secretion by platelet;GO:0010920//negative regulation of inositol phosphate biosynthetic process;GO:0030168//platelet activation;GO:0070493//thrombin receptor signaling pathway;GO:0030836//positive regulation of actin filament depolymerization;GO:0030030//cell projection organization;GO:0060305//regulation of cell diameter;GO:0007229//integrin-mediated signaling pathway;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0050849//negative regulation of calcium-mediated signaling;GO:0030845//phospholipase C-inhibiting G-protein coupled receptor signaling pathway;GO:0046488//phosphatidylinositol metabolic process;GO:0002576//platelet degranulation;GO:0010925//positive regulation of inositol-polyphosphate 5-phosphatase activity;GO:0007596//blood coagulation;GO:0030866//cortical actin cytoskeleton organization,"GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005080//protein kinase C binding",K06082//Adherens junction
5342,0,0,0,0,0,0,0,0,1,0,0,0,PLGLB2;plasminogen-like B2,-,-,-,K01315//Staphylococcus aureus infection;Influenza A;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
5345,0,0,0,0,13,0,0,54,0,0,0,0,"SERPINF2;serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0009986//cell surface;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005577//fibrinogen complex,GO:0010033//response to organic substance;GO:0010757//negative regulation of plasminogen activation;GO:0071636//positive regulation of transforming growth factor beta production;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0046330//positive regulation of JNK cascade;GO:0042730//fibrinolysis;GO:0032967//positive regulation of collagen biosynthetic process;GO:0030199//collagen fibril organization;GO:0006953//acute-phase response;GO:0051918//negative regulation of fibrinolysis;GO:0002034//regulation of blood vessel size by renin-angiotensin;GO:0030168//platelet activation;GO:0048514//blood vessel morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051496//positive regulation of stress fiber assembly;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0002576//platelet degranulation;GO:0010951//negative regulation of endopeptidase activity;GO:0045597//positive regulation of cell differentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030162//regulation of proteolysis;GO:0007596//blood coagulation,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004866//endopeptidase inhibitor activity;GO:0002020//protease binding;GO:0004867//serine-type endopeptidase inhibitor activity,K03983//Complement and coagulation cascades
5346,1,0,0,0,0,0,13,0,33,0,0,0,PLIN1;perilipin 1,GO:0005829//cytosol;GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum,GO:0044281//small molecule metabolic process;GO:0019433//triglyceride catabolic process;GO:0006629//lipid metabolic process,GO:0008289//lipid binding,K08768//PPAR signaling pathway
5347,0,0,0,0,0,32,2,0,37,0,0,0,PLK1;polo-like kinase 1,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0030496//midbody;GO:0015630//microtubule cytoskeleton;GO:0005876//spindle microtubule;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0051233//spindle midzone;GO:0000776//kinetochore;GO:0005819//spindle;GO:0000942//condensed nuclear chromosome outer kinetochore;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0008283//cell proliferation;GO:0071168//protein localization to chromatin;GO:0043066//negative regulation of apoptotic process;GO:0051726//regulation of cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031572//G2 DNA damage checkpoint;GO:0046677//response to antibiotic;GO:0007094//mitotic spindle assembly checkpoint;GO:0045862//positive regulation of proteolysis;GO:0045184//establishment of protein localization;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007092//activation of mitotic anaphase-promoting complex activity;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0001578//microtubule bundle formation;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051297//centrosome organization;GO:0000281//mitotic cytokinesis;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0000070//mitotic sister chromatid segregation;GO:0040038//polar body extrusion after meiotic divisions;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0031648//protein destabilization;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043393//regulation of protein binding;GO:0007077//mitotic nuclear envelope disassembly;GO:0000910//cytokinesis;GO:0018105//peptidyl-serine phosphorylation;GO:0007346//regulation of mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0010997//anaphase-promoting complex binding;GO:0005515//protein binding,K06631//Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation
5349,0,0,0,16,38,7,0,0,12,0,0,0,FXYD3;FXYD domain containing ion transport regulator 3,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0034707//chloride channel complex,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006821//chloride transport;GO:0055085//transmembrane transport;GO:0050790//regulation of catalytic activity,GO:0051117//ATPase binding;GO:0005254//chloride channel activity,-
535,0,0,0,0,24,0,0,122,21,0,0,0,"ATP6V0A1;ATPase, H+ transporting, lysosomal V0 subunit a1","GO:0000220//vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0042470//melanosome;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle",GO:0055085//transmembrane transport;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0008286//insulin receptor signaling pathway;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0051701//interaction with host,GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005515//protein binding;GO:0051117//ATPase binding,K02154//Metabolic pathways;Oxidative phosphorylation;Epithelial cell signaling in Helicobacter pylori infection;Lysosome;Vibrio cholerae infection;Phagosome;Collecting duct acid secretion;Rheumatoid arthritis;Synaptic vesicle cycle;Tuberculosis
5350,0,0,0,0,0,25,0,0,0,0,0,336,PLN;phospholamban,GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0033017//sarcoplasmic reticulum membrane,GO:0086036//regulation of cardiac muscle cell membrane potential;GO:0051260//protein homooligomerization;GO:0010459//negative regulation of heart rate;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0055119//relaxation of cardiac muscle;GO:0006816//calcium ion transport;GO:0048738//cardiac muscle tissue development;GO:0090281//negative regulation of calcium ion import;GO:0051480//cytosolic calcium ion homeostasis;GO:0032780//negative regulation of ATPase activity;GO:1901020//negative regulation of calcium ion transmembrane transporter activity;GO:0033574//response to testosterone;GO:0086004//regulation of cardiac muscle cell contraction;GO:0008016//regulation of heart contraction;GO:0002026//regulation of the force of heart contraction;GO:0008015//blood circulation;GO:0010043//response to zinc ion;GO:0051926//negative regulation of calcium ion transport;GO:0051924//regulation of calcium ion transport;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:1901897//regulation of relaxation of cardiac muscle;GO:0043086//negative regulation of catalytic activity,GO:0004857//enzyme inhibitor activity;GO:0005246//calcium channel regulator activity;GO:0051117//ATPase binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042030//ATPase inhibitor activity,K05852//Dilated cardiomyopathy;Calcium signaling pathway
5351,0,0,0,0,0,28,0,49,0,0,0,0,"PLOD1;procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1",GO:0005789//endoplasmic reticulum membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome,GO:0001666//response to hypoxia;GO:0030198//extracellular matrix organization;GO:0008544//epidermis development;GO:0055114//oxidation-reduction process;GO:0006464//cellular protein modification process;GO:0046947//hydroxylysine biosynthetic process,GO:0031418//L-ascorbic acid binding;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0005506//iron ion binding;GO:0042803//protein homodimerization activity,K00473//Lysine degradation
5352,112,0,0,0,0,9,1,0,28,11,0,0,"PLOD2;procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2",GO:0005789//endoplasmic reticulum membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0006464//cellular protein modification process;GO:0055114//oxidation-reduction process;GO:0030198//extracellular matrix organization;GO:0001666//response to hypoxia,GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding,K13645//Lysine degradation
5354,0,0,0,0,0,0,0,35,0,0,0,237,PLP1;proteolipid protein 1,GO:0043209//myelin sheath;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0048469//cell maturation;GO:0006954//inflammatory response;GO:0008219//cell death;GO:0014002//astrocyte development;GO:0008366//axon ensheathment;GO:0007229//integrin-mediated signaling pathway;GO:0021762//substantia nigra development;GO:0022010//central nervous system myelination;GO:0061564//axon development;GO:0042759//long-chain fatty acid biosynthetic process;GO:0007268//synaptic transmission;GO:0010628//positive regulation of gene expression,GO:0019911//structural constituent of myelin sheath;GO:0005198//structural molecule activity,-
5355,5,0,0,19,2,0,0,86,14,0,4,0,PLP2;proteolipid protein 2 (colonic epithelium-enriched),GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0034220//ion transmembrane transport;GO:0006811//ion transport;GO:0006935//chemotaxis,GO:0005515//protein binding;GO:0019956//chemokine binding;GO:0015075//ion transmembrane transporter activity,K04514//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Wnt signaling pathway;Focal adhesion;Pathogenic Escherichia coli infection;Salmonella infection;Chemokine signaling pathway;Axon guidance;Leukocyte transendothelial migration;Shigellosis;TGF-beta signaling pathway
5356,92,0,0,0,56,0,0,0,26,44,0,0,PLRG1;pleiotropic regulator 1,GO:0071013//catalytic step 2 spliceosome;GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0034504//protein localization to nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0007165//signal transduction;GO:2001141//regulation of RNA biosynthetic process",GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0004871//signal transducer activity,K12862//Spliceosome
5357,0,0,0,0,1,8,0,0,69,0,0,0,PLS1;plastin 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,GO:0005200//structural constituent of cytoskeleton;GO:0005509//calcium ion binding;GO:0051015//actin filament binding,-
5358,0,0,0,0,0,0,0,0,16,0,6,0,PLS3;plastin 3,GO:0005737//cytoplasm,GO:0060348//bone development,GO:0005509//calcium ion binding;GO:0003779//actin binding,K06115//Tight junction
5359,0,0,0,0,1,0,58,0,44,0,5,0,PLSCR1;phospholipid scramblase 1,GO:0045121//membrane raft;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0017121//phospholipid scrambling;GO:0006659//phosphatidylserine biosynthetic process;GO:2000373//positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity;GO:0030168//platelet activation;GO:0033003//regulation of mast cell activation;GO:0045089//positive regulation of innate immune response;GO:0006915//apoptotic process;GO:0045071//negative regulation of viral genome replication;GO:0006953//acute-phase response;GO:0060368//regulation of Fc receptor mediated stimulatory signaling pathway;GO:0035456//response to interferon-beta;GO:0010628//positive regulation of gene expression,GO:0005154//epidermal growth factor receptor binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0017128//phospholipid scramblase activity;GO:0005509//calcium ion binding;GO:0042609//CD4 receptor binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0003677//DNA binding;GO:0017124//SH3 domain binding,K08267//mTOR signaling pathway
5360,224,0,0,0,21,12,19,0,27,0,9,0,PLTP;phospholipid transfer protein,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0006629//lipid metabolic process;GO:0006869//lipid transport;GO:0030317//sperm motility;GO:0010189//vitamin E biosynthetic process,GO:0008289//lipid binding,K08761//PPAR signaling pathway
5361,132,0,0,0,0,27,104,0,74,142,0,354,PLXNA1;plexin A1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0002116//semaphorin receptor complex,GO:0014910//regulation of smooth muscle cell migration;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0007411//axon guidance;GO:0007275//multicellular organismal development;GO:0071526//semaphorin-plexin signaling pathway,GO:0004872//receptor activity;GO:0017154//semaphorin receptor activity,K06820//Axon guidance
53615,0,0,0,0,7,0,0,51,34,0,0,0,MBD3;methyl-CpG binding domain protein 3,GO:0005737//cytoplasm;GO:0016581//NuRD complex;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin;GO:0043234//protein complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0001701//in utero embryonic development;GO:0006351//transcription, DNA-templated;GO:0009888//tissue development;GO:0006346//methylation-dependent chromatin silencing;GO:0016573//histone acetylation",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0003677//DNA binding;GO:0008327//methyl-CpG binding;GO:0005515//protein binding,-
53616,0,0,0,0,0,5,0,0,89,0,0,332,ADAM22;ADAM metallopeptidase domain 22,GO:0016021//integral component of membrane,GO:0008344//adult locomotory behavior;GO:0007162//negative regulation of cell adhesion;GO:0007155//cell adhesion;GO:0022011//myelination in peripheral nervous system;GO:0006508//proteolysis;GO:0007417//central nervous system development,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0004222//metalloendopeptidase activity,-
5362,0,0,0,0,0,35,26,1,138,0,30,182,PLXNA2;plexin A2,GO:0005887//integral component of plasma membrane;GO:0002116//semaphorin receptor complex;GO:0005622//intracellular;GO:0005886//plasma membrane,GO:0007411//axon guidance;GO:0071526//semaphorin-plexin signaling pathway;GO:0060174//limb bud formation;GO:0021935//cerebellar granule cell precursor tangential migration;GO:0030334//regulation of cell migration;GO:0051642//centrosome localization;GO:0001756//somitogenesis;GO:0021915//neural tube development;GO:0060037//pharyngeal system development,GO:0005515//protein binding;GO:0017154//semaphorin receptor activity,K06820//Axon guidance
53630,0,0,0,0,0,7,0,0,42,0,0,0,"BCMO1;beta-carotene 15,15'-monooxygenase 1",GO:0005829//cytosol,"GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light;GO:0035238//vitamin A biosynthetic process;GO:0001523//retinoid metabolic process;GO:0055114//oxidation-reduction process;GO:0042574//retinal metabolic process","GO:0046872//metal ion binding;GO:0004497//monooxygenase activity;GO:0003834//beta-carotene 15,15'-monooxygenase activity",K00515//Retinol metabolism;Metabolic pathways
53632,0,0,0,0,0,0,29,0,32,0,0,0,"PRKAG3;protein kinase, AMP-activated, gamma 3 non-catalytic subunit",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0031588//AMP-activated protein kinase complex,GO:0006633//fatty acid biosynthetic process;GO:0007050//cell cycle arrest;GO:0005978//glycogen biosynthetic process;GO:0015758//glucose transport;GO:0006468//protein phosphorylation;GO:0061024//membrane organization;GO:0008286//insulin receptor signaling pathway;GO:0035556//intracellular signal transduction,GO:0004679//AMP-activated protein kinase activity;GO:0005524//ATP binding;GO:0019901//protein kinase binding,K07200//Hypertrophic cardiomyopathy (HCM);Adipocytokine signaling pathway;Insulin signaling pathway
53635,0,33,0,35,46,0,0,82,13,0,158,0,PTOV1;prostate tumor overexpressed 1,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
53637,0,0,0,0,10,0,0,40,24,0,0,0,S1PR5;sphingosine-1-phosphate receptor 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0045664//regulation of neuron differentiation,GO:0038036//sphingosine-1-phosphate receptor activity,K04295//Neuroactive ligand-receptor interaction
5364,0,0,0,0,7,0,4,0,38,0,0,0,PLXNB1;plexin B1,GO:0002116//semaphorin receptor complex;GO:0005576//extracellular region;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0048812//neuron projection morphogenesis;GO:0043931//ossification involved in bone maturation;GO:0051493//regulation of cytoskeleton organization;GO:0050772//positive regulation of axonogenesis;GO:0016477//cell migration;GO:0032321//positive regulation of Rho GTPase activity;GO:1900220//semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis;GO:0007411//axon guidance;GO:0035556//intracellular signal transduction;GO:0008360//regulation of cell shape;GO:0071526//semaphorin-plexin signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007162//negative regulation of cell adhesion;GO:0033689//negative regulation of osteoblast proliferation,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0032794//GTPase activating protein binding;GO:0030215//semaphorin receptor binding;GO:0017154//semaphorin receptor activity;GO:0004872//receptor activity,K06821//Axon guidance
5365,0,0,0,0,0,2,0,0,85,17,0,0,PLXNB3;plexin B3,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane,GO:0007162//negative regulation of cell adhesion;GO:0034260//negative regulation of GTPase activity;GO:0007411//axon guidance;GO:0030336//negative regulation of cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0071526//semaphorin-plexin signaling pathway;GO:0050918//positive chemotaxis;GO:0060326//cell chemotaxis;GO:0010593//negative regulation of lamellipodium assembly,GO:0005515//protein binding;GO:0051022//Rho GDP-dissociation inhibitor binding;GO:0019904//protein domain specific binding;GO:0017154//semaphorin receptor activity,K06821//Axon guidance
5366,0,0,0,0,0,0,0,68,25,0,0,0,PMAIP1;phorbol-12-myristate-13-acetate-induced protein 1,GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0043065//positive regulation of apoptotic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0010917//negative regulation of mitochondrial membrane potential;GO:0010165//response to X-ray;GO:0006915//apoptotic process;GO:0043331//response to dsRNA;GO:0051607//defense response to virus;GO:0001836//release of cytochrome c from mitochondria;GO:0032461//positive regulation of protein oligomerization;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0010498//proteasomal protein catabolic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0046902//regulation of mitochondrial membrane permeability;GO:0043525//positive regulation of neuron apoptotic process;GO:0042149//cellular response to glucose starvation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009411//response to UV;GO:0071456//cellular response to hypoxia;GO:0043029//T cell homeostasis;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0072593//reactive oxygen species metabolic process;GO:0010907//positive regulation of glucose metabolic process;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors",GO:0005515//protein binding,K10131//p53 signaling pathway
5367,0,0,0,14,0,0,0,0,23,0,0,0,PMCH;pro-melanin-concentrating hormone,GO:0005576//extracellular region;GO:0005634//nucleus,GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007268//synaptic transmission;GO:0007283//spermatogenesis,GO:0030354//melanin-concentrating hormone activity,-
5368,0,0,0,0,0,0,0,0,16,0,0,0,PNOC;prepronociceptin,GO:0005576//extracellular region,GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0007600//sensory perception;GO:0007218//neuropeptide signaling pathway,GO:0001515//opioid peptide activity;GO:0005515//protein binding;GO:0005184//neuropeptide hormone activity,-
537,0,0,0,0,0,13,0,0,31,0,11,0,"ATP6AP1;ATPase, H+ transporting, lysosomal accessory protein 1","GO:0070062//extracellular vesicular exosome;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0005774//vacuolar membrane;GO:0016021//integral component of membrane;GO:0016469//proton-transporting two-sector ATPase complex",GO:0045669//positive regulation of osteoblast differentiation;GO:0015991//ATP hydrolysis coupled proton transport;GO:0015992//proton transport;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045780//positive regulation of bone resorption;GO:0051656//establishment of organelle localization;GO:2001206//positive regulation of osteoclast development;GO:0045921//positive regulation of exocytosis;GO:0045851//pH reduction,"GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0005524//ATP binding;GO:0017137//Rab GTPase binding;GO:0005215//transporter activity",K03662//Rheumatoid arthritis;Phagosome;Tuberculosis;Oxidative phosphorylation;Metabolic pathways;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Lysosome
5371,0,1,0,0,3,32,98,1,28,5,0,370,PML;promyelocytic leukemia,GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0016605//PML body;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0042406//extrinsic component of endoplasmic reticulum membrane,"GO:0051607//defense response to virus;GO:0031065//positive regulation of histone deacetylation;GO:2000779//regulation of double-strand break repair;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043153//entrainment of circadian clock by photoperiod;GO:0019221//cytokine-mediated signaling pathway;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045165//cell fate commitment;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0090398//cellular senescence;GO:0006355//regulation of transcription, DNA-templated;GO:0007184//SMAD protein import into nucleus;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0032922//circadian regulation of gene expression;GO:0010332//response to gamma radiation;GO:0001932//regulation of protein phosphorylation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006605//protein targeting;GO:0050821//protein stabilization;GO:1902187//negative regulation of viral release from host cell;GO:0016032//viral process;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0071353//cellular response to interleukin-4;GO:0016525//negative regulation of angiogenesis;GO:0051457//maintenance of protein location in nucleus;GO:0007050//cell cycle arrest;GO:0030099//myeloid cell differentiation;GO:0042752//regulation of circadian rhythm;GO:0010522//regulation of calcium ion transport into cytosol;GO:0032938//negative regulation of translation in response to oxidative stress;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0002230//positive regulation of defense response to virus by host;GO:0045930//negative regulation of mitotic cell cycle;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0048384//retinoic acid receptor signaling pathway;GO:0045343//regulation of MHC class I biosynthetic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030578//PML body organization;GO:0006351//transcription, DNA-templated;GO:0009411//response to UV;GO:0030308//negative regulation of cell growth;GO:0051974//negative regulation of telomerase activity;GO:0007182//common-partner SMAD protein phosphorylation;GO:0008285//negative regulation of cell proliferation",GO:0050897//cobalt ion binding;GO:0008270//zinc ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0032183//SUMO binding;GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0003713//transcription coactivator activity;GO:0046332//SMAD binding,K10054//Ubiquitin mediated proteolysis;Influenza A;Transcriptional misregulation in cancer;Endocytosis;Acute myeloid leukemia;Herpes simplex infection;Pathways in cancer
5372,0,1,0,14,0,0,0,0,0,0,0,0,PMM1;phosphomannomutase 1,GO:0043025//neuronal cell body;GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0019307//mannose biosynthetic process;GO:0006013//mannose metabolic process;GO:0043687//post-translational protein modification;GO:0009298//GDP-mannose biosynthetic process,GO:0004615//phosphomannomutase activity;GO:0046872//metal ion binding,K01840//Amino sugar and nucleotide sugar metabolism;Arginine and proline metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;ABC transporters;Fructose and mannose metabolism
5373,0,34,0,1,1,8,0,0,0,0,0,0,PMM2;phosphomannomutase 2,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0043025//neuronal cell body,GO:0006486//protein glycosylation;GO:0043687//post-translational protein modification;GO:0009298//GDP-mannose biosynthetic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0019307//mannose biosynthetic process,GO:0004615//phosphomannomutase activity,K01840//ABC transporters;Metabolic pathways;Fructose and mannose metabolism;Biosynthesis of secondary metabolites;Arginine and proline metabolism;Amino sugar and nucleotide sugar metabolism
5375,39,0,0,0,0,0,28,0,15,13,0,0,PMP2;peripheral myelin protein 2,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006810//transport;GO:0061024//membrane organization,GO:0015485//cholesterol binding;GO:0005215//transporter activity;GO:0005504//fatty acid binding,K08753//PPAR signaling pathway
5376,9,0,0,0,0,0,30,0,22,0,9,0,PMP22;peripheral myelin protein 22,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007422//peripheral nervous system development;GO:0008219//cell death;GO:0007268//synaptic transmission,GO:0005515//protein binding,K08341//GABAergic synapse;Regulation of autophagy
5378,166,0,0,15,83,37,0,0,16,34,40,0,PMS1;PMS1 postmeiotic segregation increased 1 (S. cerevisiae),GO:0032389//MutLalpha complex;GO:0005634//nucleus,GO:0042493//response to drug;GO:0006298//mismatch repair;GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0003677//DNA binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0030983//mismatched DNA binding,-
5379,0,23,0,12,15,0,0,0,0,0,0,0,PMS2P1;postmeiotic segregation increased 2 pseudogene 1,GO:0032300//mismatch repair complex,GO:0006298//mismatch repair;GO:0016310//phosphorylation,GO:0016301//kinase activity,K10858//Mismatch repair;Fanconi anemia pathway
538,106,0,0,0,25,20,65,30,85,0,0,0,"ATP7A;ATPase, Cu++ transporting, alpha polypeptide",GO:0048471//perinuclear region of cytoplasm;GO:0030141//secretory granule;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane;GO:0005802//trans-Golgi network;GO:0043025//neuronal cell body;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0043005//neuron projection;GO:0005783//endoplasmic reticulum;GO:0030140//trans-Golgi network transport vesicle;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0031526//brush border membrane,GO:0007595//lactation;GO:0043524//negative regulation of neuron apoptotic process;GO:0010043//response to zinc ion;GO:0007005//mitochondrion organization;GO:0006570//tyrosine metabolic process;GO:0018205//peptidyl-lysine modification;GO:0042414//epinephrine metabolic process;GO:0046034//ATP metabolic process;GO:0021860//pyramidal neuron development;GO:0007626//locomotory behavior;GO:0001568//blood vessel development;GO:0051216//cartilage development;GO:0048553//negative regulation of metalloenzyme activity;GO:0021702//cerebellar Purkinje cell differentiation;GO:0030199//collagen fibril organization;GO:0048813//dendrite morphogenesis;GO:0051353//positive regulation of oxidoreductase activity;GO:0043588//skin development;GO:0042417//dopamine metabolic process;GO:0051542//elastin biosynthetic process;GO:0001836//release of cytochrome c from mitochondria;GO:0021954//central nervous system neuron development;GO:0006878//cellular copper ion homeostasis;GO:0002082//regulation of oxidative phosphorylation;GO:0048554//positive regulation of metalloenzyme activity;GO:0042093//T-helper cell differentiation;GO:0048251//elastic fiber assembly;GO:0006825//copper ion transport;GO:0010041//response to iron(III) ion;GO:0010468//regulation of gene expression;GO:0010273//detoxification of copper ion;GO:0034220//ion transmembrane transport;GO:0043085//positive regulation of catalytic activity;GO:0042421//norepinephrine biosynthetic process;GO:0001701//in utero embryonic development;GO:0042415//norepinephrine metabolic process;GO:0042428//serotonin metabolic process;GO:0030198//extracellular matrix organization;GO:0031069//hair follicle morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0043473//pigmentation;GO:0060003//copper ion export;GO:0006584//catecholamine metabolic process;GO:0019430//removal of superoxide radicals;GO:0001974//blood vessel remodeling;GO:0048286//lung alveolus development;GO:0015677//copper ion import;GO:0055085//transmembrane transport;GO:0006568//tryptophan metabolic process,GO:0032767//copper-dependent protein binding;GO:0005515//protein binding;GO:0004008//copper-exporting ATPase activity;GO:0005524//ATP binding;GO:0005507//copper ion binding;GO:0016532//superoxide dismutase copper chaperone activity;GO:0005375//copper ion transmembrane transporter activity,K01533//Mineral absorption
5380,0,0,1,0,1,0,0,0,0,0,0,0,PMS2L2;postmeiotic segregation increased 2-like 2 pseudogene,-,-,-,K10858//Mismatch repair;Fanconi anemia pathway
5382,0,0,0,0,0,0,0,0,16,0,0,0,PMS2P4;postmeiotic segregation increased 2 pseudogene 4,-,-,-,K10858//Fanconi anemia pathway;Mismatch repair
53820,0,0,0,0,0,0,0,63,0,0,0,0,RIPPLY3;ripply transcriptional repressor 3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0060037//pharyngeal system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007507//heart development",-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
53822,0,0,0,0,0,0,0,57,0,0,0,0,FXYD7;FXYD domain containing ion transport regulator 7,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0043269//regulation of ion transport;GO:0034220//ion transmembrane transport,GO:0005216//ion channel activity;GO:0051117//ATPase binding,-
53826,0,26,0,0,0,14,0,0,10,1,0,0,FXYD6;FXYD domain containing ion transport regulator 6,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005216//ion channel activity,-
53827,0,0,0,0,0,27,0,0,10,0,0,0,FXYD5;FXYD domain containing ion transport regulator 5,GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0030033//microvillus assembly;GO:0046588//negative regulation of calcium-dependent cell-cell adhesion,GO:0003779//actin binding;GO:0005216//ion channel activity;GO:0045296//cadherin binding,-
53828,0,0,0,0,0,11,0,0,0,0,0,0,FXYD4;FXYD domain containing ion transport regulator 4,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport,GO:0005216//ion channel activity,K13359//Aldosterone-regulated sodium reabsorption
53829,0,0,0,0,0,0,21,0,27,0,0,0,"P2RY13;purinergic receptor P2Y, G-protein coupled, 13",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,GO:0007194//negative regulation of adenylate cyclase activity;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0045028//G-protein coupled purinergic nucleotide receptor activity,K08388//Neuroactive ligand-receptor interaction
5383,0,0,0,11,0,0,0,0,11,0,7,0,PMS2P5;postmeiotic segregation increased 2 pseudogene 5,GO:0032300//mismatch repair complex,GO:0006298//mismatch repair,-,K10858//Fanconi anemia pathway;Mismatch repair
53831,0,0,0,0,0,0,0,0,0,110,0,0,GPR84;G protein-coupled receptor 84,GO:0043235//receptor complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
53832,0,0,0,9,16,22,19,0,34,0,0,0,"IL20RA;interleukin 20 receptor, alpha",GO:0016021//integral component of membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0045124//regulation of bone resorption;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway,GO:0042015//interleukin-20 binding,K05136//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
53833,0,0,0,0,0,14,0,0,0,0,8,0,IL20RB;interleukin 20 receptor beta,GO:0016021//integral component of membrane,GO:0032753//positive regulation of interleukin-4 production;GO:0032703//negative regulation of interleukin-2 production;GO:0032689//negative regulation of interferon-gamma production;GO:0001808//negative regulation of type IV hypersensitivity;GO:0042130//negative regulation of T cell proliferation;GO:0002437//inflammatory response to antigenic stimulus;GO:0032733//positive regulation of interleukin-10 production;GO:0048873//homeostasis of number of cells within a tissue;GO:0002765//immune response-inhibiting signal transduction,GO:0042015//interleukin-20 binding,K05137//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
53834,0,0,0,0,2,0,20,0,15,98,0,0,FGFRL1;fibroblast growth factor receptor-like 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0003179//heart valve morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0001501//skeletal system development;GO:0060539//diaphragm development;GO:0008285//negative regulation of cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0008201//heparin binding;GO:0005007//fibroblast growth factor-activated receptor activity;GO:0017134//fibroblast growth factor binding,K05095//MAPK signaling pathway;Endocytosis;Regulation of actin cytoskeleton;K05094//Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Endocytosis;Bladder cancer;K01217//Metabolic pathways;Glycosaminoglycan degradation;Lysosome
53836,0,0,0,0,0,33,0,1,0,0,0,0,GPR87;G protein-coupled receptor 87,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007194//negative regulation of adenylate cyclase activity;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0045028//G-protein coupled purinergic nucleotide receptor activity,-
53838,0,0,0,0,0,11,0,0,0,0,0,0,C11orf24;chromosome 11 open reading frame 24,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,-,-,-
53840,0,0,0,11,0,0,0,0,0,0,0,0,TRIM34;tripartite motif containing 34,GO:0005737//cytoplasm,GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0070206//protein trimerization,GO:0008270//zinc ion binding,-
53841,0,0,0,0,0,25,0,41,4,0,11,0,CDHR5;cadherin-related family member 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0008013//beta-catenin binding;GO:0005509//calcium ion binding,K14000//Protein processing in endoplasmic reticulum
53842,0,25,0,19,76,4,1,0,62,0,24,0,CLDN22;claudin 22,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//tight junction assembly,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Hepatitis C;Cell adhesion molecules (CAMs);Tight junction;Leukocyte transendothelial migration;Pathogenic Escherichia coli infection
5387,0,0,0,0,9,0,0,0,32,54,0,0,PMS2P3;postmeiotic segregation increased 2 pseudogene 3,GO:0032300//mismatch repair complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006298//mismatch repair",GO:0003676//nucleic acid binding,K10858//Fanconi anemia pathway;Mismatch repair
539,0,0,0,26,33,0,32,0,11,0,0,0,"ATP5O;ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit",GO:0005634//nucleus;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005743//mitochondrial inner membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0015992//proton transport;GO:0006754//ATP biosynthetic process;GO:0022904//respiratory electron transport chain;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport;GO:0044237//cellular metabolic process,"GO:0008144//drug binding;GO:0005215//transporter activity;GO:0022857//transmembrane transporter activity;GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0016887//ATPase activity",K02137//Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways
53904,130,0,0,11,0,22,0,178,67,0,4,0,MYO3A;myosin IIIA,GO:0005737//cytoplasm;GO:0032426//stereocilium bundle tip;GO:0001917//photoreceptor inner segment;GO:0016459//myosin complex;GO:0032433//filopodium tip;GO:0030175//filopodium;GO:0031941//filamentous actin,GO:0007605//sensory perception of sound;GO:0051491//positive regulation of filopodium assembly;GO:0018105//peptidyl-serine phosphorylation;GO:0006200//ATP catabolic process;GO:0007601//visual perception;GO:0048839//inner ear development;GO:0046777//protein autophosphorylation;GO:0050896//response to stimulus;GO:0018107//peptidyl-threonine phosphorylation,GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0004672//protein kinase activity;GO:0051015//actin filament binding;GO:0030898//actin-dependent ATPase activity;GO:0043531//ADP binding;GO:0060002//plus-end directed microfilament motor activity;GO:0000146//microfilament motor activity;GO:0004674//protein serine/threonine kinase activity,K08834//Phototransduction - fly
53905,8,0,15,0,16,8,0,19,67,0,34,0,DUOX1;dual oxidase 1,GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane,GO:0006590//thyroid hormone generation;GO:0042446//hormone biosynthetic process;GO:0051591//response to cAMP;GO:0042744//hydrogen peroxide catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0050665//hydrogen peroxide biosynthetic process;GO:0042335//cuticle development;GO:0055114//oxidation-reduction process;GO:0042554//superoxide anion generation,GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0050661//NADP binding;GO:0005509//calcium ion binding;GO:0016174//NAD(P)H oxidase activity,-
53917,0,8,0,10,2,0,0,0,20,0,0,0,"RAB24;RAB24, member RAS oncogene family",GO:0005829//cytosol;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005776//autophagic vacuole,GO:0015031//protein transport;GO:0006914//autophagy;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding,-
53918,0,0,0,6,26,38,20,0,16,0,0,0,PELO;pelota homolog (Drosophila),GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0071025//RNA surveillance;GO:0008283//cell proliferation;GO:0051276//chromosome organization;GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0007049//cell cycle;GO:0051301//cell division;GO:0070481//nuclear-transcribed mRNA catabolic process, non-stop decay",GO:0004519//endonuclease activity;GO:0046872//metal ion binding,K06965//mRNA surveillance pathway
53919,85,0,0,0,0,9,0,50,72,0,0,0,"SLCO1C1;solute carrier organic anion transporter family, member 1C1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0043252//sodium-independent organic anion transport,GO:0005215//transporter activity,-
5393,0,0,1,5,51,0,0,0,0,0,8,0,EXOSC9;exosome component 9,GO:0000176//nuclear exosome (RNase complex);GO:0005634//nucleus;GO:0000178//exosome (RNase complex);GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton,"GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0071028//nuclear mRNA surveillance;GO:0006364//rRNA processing;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0030307//positive regulation of cell growth;GO:0006955//immune response;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0003723//RNA binding;GO:0004532//exoribonuclease activity;GO:0017091//AU-rich element binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000175//3'-5'-exoribonuclease activity,K03678//RNA degradation
53938,0,23,0,0,22,0,0,0,0,0,1,0,PPIL3;peptidylprolyl isomerase (cyclophilin)-like 3,GO:0071013//catalytic step 2 spliceosome,"GO:0006457//protein folding;GO:0000398//mRNA splicing, via spliceosome;GO:0000413//protein peptidyl-prolyl isomerization",GO:0005515//protein binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
5394,0,1,0,0,1,0,61,0,48,79,0,0,EXOSC10;exosome component 10,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000178//exosome (RNase complex);GO:0000176//nuclear exosome (RNase complex);GO:0005730//nucleolus;GO:0035327//transcriptionally active chromatin;GO:0016020//membrane,"GO:0071028//nuclear mRNA surveillance;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0071035//nuclear polyadenylation-dependent rRNA catabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0071034//CUT catabolic process;GO:0071048//nuclear retention of unspliced pre-mRNA at the site of transcription;GO:0071044//histone mRNA catabolic process;GO:0000460//maturation of 5.8S rRNA",GO:0004532//exoribonuclease activity;GO:0044822//poly(A) RNA binding;GO:0008408//3'-5' exonuclease activity;GO:0005515//protein binding;GO:0000166//nucleotide binding,K12591//RNA degradation
53940,0,0,0,0,0,0,0,0,10,0,0,1,"FTHL17;ferritin, heavy polypeptide-like 17",-,GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis,GO:0008199//ferric iron binding,K00522//Porphyrin and chlorophyll metabolism;Mineral absorption
53942,0,0,0,0,0,0,34,0,41,0,15,0,CNTN5;contactin 5,GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0007605//sensory perception of sound,-,-
53944,164,1,0,17,26,16,14,0,34,0,6,0,"CSNK1G1;casein kinase 1, gamma 1",GO:0005737//cytoplasm,GO:0016055//Wnt signaling pathway;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K08958//Hedgehog signaling pathway
53947,0,10,0,5,0,0,0,0,0,0,16,0,"A4GALT;alpha 1,4-galactosyltransferase",GO:0016020//membrane;GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular vesicular exosome,GO:0007009//plasma membrane organization;GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process,GO:0015643//toxic substance binding;GO:0050512//lactosylceramide 4-alpha-galactosyltransferase activity;GO:0008378//galactosyltransferase activity,K01988//Glycosphingolipid biosynthesis - globo series;Metabolic pathways
5395,0,49,0,1,0,0,0,0,2,5,4,0,PMS2;PMS2 postmeiotic segregation increased 2 (S. cerevisiae),GO:0015630//microtubule cytoskeleton;GO:0032389//MutLalpha complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006298//mismatch repair;GO:0042493//response to drug;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0006200//ATP catabolic process;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0032138//single base insertion or deletion binding;GO:0003697//single-stranded DNA binding;GO:0032407//MutSalpha complex binding;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,K10858//Fanconi anemia pathway;Mismatch repair
5396,0,0,0,0,0,35,0,0,45,0,0,0,PRRX1;paired related homeobox 1,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0045880//positive regulation of smoothened signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060021//palate development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0042474//middle ear morphogenesis;GO:0048844//artery morphogenesis;GO:0051216//cartilage development,GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding;GO:0003713//transcription coactivator activity,-
53981,0,42,0,54,139,18,60,27,55,1,26,0,"CPSF2;cleavage and polyadenylation specific factor 2, 100kDa",GO:0016020//membrane;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0006379//mRNA cleavage;GO:0006398//histone mRNA 3'-end processing",GO:0003723//RNA binding;GO:0005515//protein binding,K14402//mRNA surveillance pathway
54,0,0,0,0,15,0,0,0,3,24,21,138,"ACP5;acid phosphatase 5, tartrate resistant",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005764//lysosome,GO:0032691//negative regulation of interleukin-1 beta production;GO:0032496//response to lipopolysaccharide;GO:0016311//dephosphorylation;GO:0032695//negative regulation of interleukin-12 production;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0034097//response to cytokine;GO:0060349//bone morphogenesis;GO:0006766//vitamin metabolic process;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006771//riboflavin metabolic process;GO:0045453//bone resorption;GO:0050728//negative regulation of inflammatory response;GO:0032929//negative regulation of superoxide anion generation;GO:0050830//defense response to Gram-positive bacterium;GO:0045019//negative regulation of nitric oxide biosynthetic process,GO:0008198//ferrous iron binding;GO:0003993//acid phosphatase activity;GO:0008199//ferric iron binding,K14379//Riboflavin metabolism;Lysosome;Osteoclast differentiation;Rheumatoid arthritis
540,88,0,52,0,0,0,22,178,40,0,12,0,"ATP7B;ATPase, Cu++ transporting, beta polypeptide",GO:0016323//basolateral plasma membrane;GO:0005739//mitochondrion;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016020//membrane;GO:0005770//late endosome;GO:0000139//Golgi membrane;GO:0005802//trans-Golgi network,GO:0007595//lactation;GO:0015680//intracellular copper ion transport;GO:0006878//cellular copper ion homeostasis;GO:0006882//cellular zinc ion homeostasis;GO:0046688//response to copper ion;GO:0006825//copper ion transport;GO:0060003//copper ion export;GO:0015677//copper ion import;GO:0051208//sequestering of calcium ion;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0004008//copper-exporting ATPase activity;GO:0005507//copper ion binding;GO:0005524//ATP binding,K01533//Mineral absorption
54014,0,31,1,46,204,71,32,58,163,0,7,0,BRWD1;bromodomain and WD repeat domain containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization;GO:0006357//regulation of transcription from RNA polymerase II promoter",-,-
54020,0,0,0,0,1,19,0,0,24,0,11,0,"SLC37A1;solute carrier family 37 (glucose-6-phosphate transporter), member 1",GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
54033,0,0,0,7,0,0,0,0,4,0,3,0,RBM11;RNA binding motif protein 11,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0034599//cellular response to oxidative stress;GO:0030154//cell differentiation;GO:0006397//mRNA processing;GO:0007275//multicellular organismal development;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0042803//protein homodimerization activity;GO:0008266//poly(U) RNA binding,-
54039,0,0,0,0,0,33,0,0,30,0,0,0,PCBP3;poly(rC) binding protein 3,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0005829//cytosol,GO:0016071//mRNA metabolic process,GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,-
54058,0,28,71,0,0,44,0,0,0,162,12,0,C21orf58;chromosome 21 open reading frame 58,-,-,-,K06264//ECM-receptor interaction
54059,0,58,0,6,25,16,0,0,28,0,9,0,YBEY;ybeY metallopeptidase (putative),GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006508//proteolysis;GO:0006364//rRNA processing,GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity,-
5406,0,0,0,0,0,0,0,0,45,0,0,0,PNLIP;pancreatic lipase,GO:0005576//extracellular region,"GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light;GO:0030299//intestinal cholesterol absorption;GO:0044241//lipid digestion;GO:0016042//lipid catabolic process;GO:0044281//small molecule metabolic process",GO:0046872//metal ion binding;GO:0004806//triglyceride lipase activity,K14073//Metabolic pathways;Vitamin digestion and absorption;Fat digestion and absorption;Glycerolipid metabolism;Pancreatic secretion
54065,0,0,0,0,0,0,35,0,0,0,0,0,SMIM11;small integral membrane protein 11,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
54069,0,0,0,5,0,0,20,0,30,0,7,0,MIS18A;MIS18 kinetochore protein A,"GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm",GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation;GO:0034080//CENP-A containing nucleosome assembly;GO:0044030//regulation of DNA methylation;GO:0006334//nucleosome assembly,-,-
5407,0,0,0,0,9,0,0,0,24,0,0,0,PNLIPRP1;pancreatic lipase-related protein 1,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006629//lipid metabolic process,GO:0016298//lipase activity;GO:0005509//calcium ion binding;GO:0004806//triglyceride lipase activity,K14074//Pancreatic secretion;Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism
5408,0,0,0,0,0,2,0,52,0,0,0,0,PNLIPRP2;pancreatic lipase-related protein 2,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0006641//triglyceride metabolic process;GO:0009395//phospholipid catabolic process;GO:0044281//small molecule metabolic process;GO:0044241//lipid digestion;GO:0019376//galactolipid catabolic process,GO:0047714//galactolipase activity;GO:0004620//phospholipase activity;GO:0005509//calcium ion binding;GO:0047372//acylglycerol lipase activity;GO:0004806//triglyceride lipase activity,K14075//Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism;Pancreatic secretion
54084,0,0,0,0,0,30,0,26,10,0,0,0,TSPEAR;thrombospondin-type laminin G domain and EAR repeats,GO:0032420//stereocilium;GO:0060170//ciliary membrane;GO:0005576//extracellular region;GO:0009986//cell surface,GO:0007605//sensory perception of sound,-,K06236//Protein digestion and absorption;Amoebiasis;Focal adhesion;ECM-receptor interaction
5409,75,0,0,0,0,0,0,0,0,0,0,0,PNMT;phenylethanolamine N-methyltransferase,GO:0005829//cytosol,GO:0034641//cellular nitrogen compound metabolic process;GO:0042423//catecholamine biosynthetic process;GO:0042418//epinephrine biosynthetic process;GO:0032259//methylation;GO:0044281//small molecule metabolic process,GO:0004603//phenylethanolamine N-methyltransferase activity,K00553//Tyrosine metabolism;Metabolic pathways
54093,0,0,0,1,11,13,21,22,4,11,3,0,SETD4;SET domain containing 4,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K05662//ABC transporters
54097,0,1,0,4,21,0,0,0,0,0,14,0,"FAM3B;family with sequence similarity 3, member B",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0030073//insulin secretion;GO:0006915//apoptotic process,GO:0005125//cytokine activity,K09633//Influenza A;Transcriptional misregulation in cancer;K09666//Other types of O-glycan biosynthesis
54101,0,4,0,0,8,14,6,0,47,0,0,0,RIPK4;receptor-interacting serine-threonine kinase 4,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002009//morphogenesis of an epithelium,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
54102,72,0,0,0,39,13,0,0,33,0,0,0,CLIC6;chloride intracellular channel 6,GO:0005737//cytoplasm;GO:0034707//chloride channel complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0034765//regulation of ion transmembrane transport;GO:0044070//regulation of anion transport;GO:1902476//chloride transmembrane transport,GO:0031749//D2 dopamine receptor binding;GO:0008022//protein C-terminus binding;GO:0031751//D4 dopamine receptor binding;GO:0005247//voltage-gated chloride channel activity;GO:0042803//protein homodimerization activity;GO:0031750//D3 dopamine receptor binding,-
54103,111,0,0,0,1,0,0,0,1,0,0,0,GSAP;gamma-secretase activating protein,GO:0005802//trans-Golgi network,GO:0030162//regulation of proteolysis;GO:1902004//positive regulation of beta-amyloid formation,GO:0001540//beta-amyloid binding,-
54106,0,0,0,0,0,0,22,0,43,0,16,0,TLR9;toll-like receptor 9,GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0032009//early phagosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0010008//endosome membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005768//endosome;GO:0005764//lysosome;GO:0005789//endoplasmic reticulum membrane;GO:0036020//endolysosome membrane;GO:0016323//basolateral plasma membrane,GO:0032760//positive regulation of tumor necrosis factor production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0032733//positive regulation of interleukin-10 production;GO:0002224//toll-like receptor signaling pathway;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032717//negative regulation of interleukin-8 production;GO:0045356//positive regulation of interferon-alpha biosynthetic process;GO:0032715//negative regulation of interleukin-6 production;GO:0006954//inflammatory response;GO:0032741//positive regulation of interleukin-18 production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0043507//positive regulation of JUN kinase activity;GO:0050707//regulation of cytokine secretion;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0050829//defense response to Gram-negative bacterium;GO:0032728//positive regulation of interferon-beta production;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0032722//positive regulation of chemokine production;GO:0045087//innate immune response;GO:0042742//defense response to bacterium;GO:0046330//positive regulation of JNK cascade;GO:0030277//maintenance of gastrointestinal epithelium;GO:0007252//I-kappaB phosphorylation;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0034162//toll-like receptor 9 signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0008286//insulin receptor signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0050729//positive regulation of inflammatory response,GO:0004888//transmembrane signaling receptor activity;GO:0005149//interleukin-1 receptor binding;GO:0035197//siRNA binding,K10161//Toll-like receptor signaling pathway;African trypanosomiasis;Tuberculosis;Measles;Chagas disease (American trypanosomiasis);Herpes simplex infection;Malaria
54107,0,0,0,31,51,1,1,0,8,0,10,0,"POLE3;polymerase (DNA directed), epsilon 3, accessory subunit",GO:0008622//epsilon DNA polymerase complex;GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,GO:0006261//DNA-dependent DNA replication;GO:0043966//histone H3 acetylation;GO:0006260//DNA replication,GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003887//DNA-directed DNA polymerase activity,K02326//Metabolic pathways;Nucleotide excision repair;HTLV-I infection;DNA replication;Purine metabolism;Pyrimidine metabolism;Base excision repair
54108,0,0,0,3,50,20,0,0,48,0,21,0,CHRAC1;chromatin accessibility complex 1,GO:0008623//CHRAC;GO:0008622//epsilon DNA polymerase complex,GO:0006338//chromatin remodeling;GO:0006261//DNA-dependent DNA replication,GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003887//DNA-directed DNA polymerase activity,K11447//Transcriptional misregulation in cancer
5411,106,60,1,31,183,0,0,0,38,0,12,0,"PNN;pinin, desmosome associated protein",GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005882//intermediate filament;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0030057//desmosome;GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0016607//nuclear speck,"GO:0006355//regulation of transcription, DNA-templated;GO:0007155//cell adhesion;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome",GO:0003677//DNA binding;GO:0005198//structural molecule activity;GO:0044822//poly(A) RNA binding,K13114//mRNA surveillance pathway;RNA transport
54112,4,0,0,15,37,0,10,97,54,0,13,0,GPR88;G protein-coupled receptor 88,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007626//locomotory behavior;GO:0007186//G-protein coupled receptor signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:0019228//neuronal action potential,GO:0004930//G-protein coupled receptor activity,-
5412,0,52,1,74,93,0,28,0,25,0,15,0,UBL3;ubiquitin-like 3,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005886//plasma membrane,-,-,-
5413,0,0,0,0,0,12,0,0,0,0,0,0,SEPT5;septin 5,GO:0043195//terminal bouton;GO:0005886//plasma membrane;GO:0031105//septin complex;GO:0008021//synaptic vesicle,GO:0000910//cytokinesis;GO:2000300//regulation of synaptic vesicle exocytosis;GO:0017157//regulation of exocytosis;GO:0006184//GTP catabolic process;GO:0016080//synaptic vesicle targeting,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K04557//Parkinson's disease
5414,8,0,14,0,0,10,5,0,0,0,6,13,SEPT4;septin 4,GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0097227//sperm annulus,GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0048240//sperm capacitation;GO:0006915//apoptotic process;GO:0006184//GTP catabolic process;GO:0007420//brain development;GO:0043065//positive regulation of apoptotic process;GO:0051301//cell division;GO:0042981//regulation of apoptotic process;GO:0031398//positive regulation of protein ubiquitination;GO:0007049//cell cycle;GO:0030382//sperm mitochondrion organization,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005198//structural molecule activity,K04557//Parkinson's disease
541468,0,0,0,0,0,6,0,0,37,0,4,0,LURAP1;leucine rich adaptor protein 1,GO:0042641//actomyosin;GO:0005737//cytoplasm,GO:0031032//actomyosin structure organization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001819//positive regulation of cytokine production;GO:0016477//cell migration,-,K05767//Regulation of actin cytoskeleton;Adherens junction;K11447//Transcriptional misregulation in cancer
541473,0,0,0,0,10,0,0,0,0,0,0,0,"LOC541473;FK506 binding protein 6, 36kDa pseudogene",-,-,-,-
54148,0,0,0,10,0,43,0,0,29,0,0,0,MRPL39;mitochondrial ribosomal protein L39,GO:0005761//mitochondrial ribosome,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K01868//Metabolic pathways;Vitamin B6 metabolism;Aminoacyl-tRNA biosynthesis
54149,0,0,0,1,16,15,0,0,84,0,0,0,C21orf91;chromosome 21 open reading frame 91,-,-,-,-
541565,0,11,441,18,41,0,78,521,85,0,70,1,C8orf58;chromosome 8 open reading frame 58,-,-,-,-
541578,0,0,0,0,23,0,0,0,29,0,0,0,CXorf40B;chromosome X open reading frame 40B,-,-,-,-
54165,0,48,0,22,74,0,28,0,45,0,0,0,"DCUN1D1;DCN1, defective in cullin neddylation 1, domain containing 1",GO:0000151//ubiquitin ligase complex,-,GO:0005515//protein binding,-
54187,0,244,20,163,412,0,0,58,1,1,88,1,NANS;N-acetylneuraminic acid synthase,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0009103//lipopolysaccharide biosynthetic process,GO:0050462//N-acetylneuraminate synthase activity;GO:0008781//N-acylneuraminate cytidylyltransferase activity;GO:0047444//N-acylneuraminate-9-phosphate synthase activity,K05304//Metabolic pathways;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
5420,84,0,0,0,0,1,0,0,31,2,0,2,PODXL;podocalyxin-like,GO:0045121//membrane raft;GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0036057//slit diaphragm;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0044297//cell body;GO:0016324//apical plasma membrane;GO:0005615//extracellular space;GO:0031528//microvillus membrane;GO:0005887//integral component of plasma membrane,GO:0016477//cell migration;GO:0072175//epithelial tube formation;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0022408//negative regulation of cell-cell adhesion;GO:0050900//leukocyte migration;GO:0007162//negative regulation of cell adhesion;GO:0072015//glomerular visceral epithelial cell development;GO:0007155//cell adhesion;GO:0032534//regulation of microvillus assembly;GO:0030335//positive regulation of cell migration,GO:0005515//protein binding,-
54205,0,31,1,52,125,0,0,0,22,118,0,0,"CYCS;cytochrome c, somatic",GO:0070469//respiratory chain;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus;GO:0000159//protein phosphatase type 2A complex,GO:0006309//apoptotic DNA fragmentation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0006915//apoptotic process;GO:0045333//cellular respiration;GO:0016311//dephosphorylation;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain,"GO:0045155//electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity;GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0020037//heme binding;GO:0004722//protein serine/threonine phosphatase activity",K08738//Amyotrophic lateral sclerosis (ALS);Herpes simplex infection;Apoptosis;Two-component system;Viral myocarditis;Colorectal cancer;Huntington's disease;Parkinson's disease;Pathways in cancer;Influenza A;Small cell lung cancer;Tuberculosis;Alzheimer's disease;Toxoplasmosis;p53 signaling pathway;Legionellosis
54206,0,0,1,1,13,0,25,0,0,27,0,0,ERRFI1;ERBB receptor feedback inhibitor 1,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0048286//lung alveolus development;GO:0032321//positive regulation of Rho GTPase activity;GO:0060426//lung vasculature development;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0006950//response to stress;GO:0045616//regulation of keratinocyte differentiation;GO:0031953//negative regulation of protein autophosphorylation;GO:0060428//lung epithelium development;GO:0043589//skin morphogenesis,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0005100//Rho GTPase activator activity,-
54207,0,0,0,0,0,10,49,0,0,0,0,0,"KCNK10;potassium channel, subfamily K, member 10",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006810//transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0007165//signal transduction,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,K04920//Gastric acid secretion
54209,0,6,0,0,0,0,0,0,0,0,4,0,TREM2;triggering receptor expressed on myeloid cells 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006959//humoral immune response;GO:0007411//axon guidance;GO:1903078//positive regulation of protein localization to plasma membrane;GO:0045087//innate immune response;GO:0050850//positive regulation of calcium-mediated signaling;GO:0002588//positive regulation of antigen processing and presentation of peptide antigen via MHC class II;GO:2000350//positive regulation of CD40 signaling pathway;GO:0097028//dendritic cell differentiation;GO:1903082//positive regulation of C-C chemokine receptor CCR7 signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation,GO:0001530//lipopolysaccharide binding;GO:0097110//scaffold protein binding;GO:0004872//receptor activity,K14378//Osteoclast differentiation
54210,0,0,0,0,0,0,12,0,38,0,0,0,TREM1;triggering receptor expressed on myeloid cells 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0035556//intracellular signal transduction;GO:0050900//leukocyte migration;GO:0072672//neutrophil extravasation;GO:0030593//neutrophil chemotaxis;GO:0007596//blood coagulation;GO:0045087//innate immune response;GO:0006959//humoral immune response,GO:0004872//receptor activity;GO:0097110//scaffold protein binding,-
54212,0,0,0,0,0,0,0,0,27,0,0,0,"SNTG1;syntrophin, gamma 1",GO:0016013//syntrophin complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0032587//ruffle membrane,GO:0007154//cell communication,GO:0003779//actin binding;GO:0008022//protein C-terminus binding,K05629//Tight junction;K05631//Tight junction
5422,96,0,0,0,55,28,41,0,59,29,16,0,"POLA1;polymerase (DNA directed), alpha 1, catalytic subunit",GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005658//alpha DNA polymerase:primase complex;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0000731//DNA synthesis involved in DNA repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000278//mitotic cell cycle;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0006260//DNA replication;GO:0000722//telomere maintenance via recombination;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006273//lagging strand elongation;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0006270//DNA replication initiation;GO:0008283//cell proliferation;GO:0000723//telomere maintenance;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006272//leading strand elongation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0019985//translesion synthesis","GO:0046872//metal ion binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0001882//nucleoside binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003896//DNA primase activity;GO:0003677//DNA binding;GO:0008408//3'-5' exonuclease activity;GO:0019901//protein kinase binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003682//chromatin binding",K02320//Metabolic pathways;DNA replication;Purine metabolism;Pyrimidine metabolism
54221,61,0,0,0,1,0,0,67,1,0,2,177,"SNTG2;syntrophin, gamma 2",GO:0005737//cytoplasm;GO:0016013//syntrophin complex;GO:0005856//cytoskeleton;GO:0042383//sarcolemma,GO:0007417//central nervous system development,GO:0030165//PDZ domain binding;GO:0003779//actin binding,K06092//Tight junction
5423,0,0,0,26,7,24,0,0,0,0,0,0,"POLB;polymerase (DNA directed), beta",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005876//spindle microtubule;GO:0005874//microtubule,"GO:0071897//DNA biosynthetic process;GO:0006284//base-excision repair;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0051402//neuron apoptotic process;GO:0006287//base-excision repair, gap-filling;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006290//pyrimidine dimer repair;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006261//DNA-dependent DNA replication;GO:0045471//response to ethanol",GO:0016829//lyase activity;GO:0008017//microtubule binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003684//damaged DNA binding;GO:0019899//enzyme binding,K02330//Base excision repair;HTLV-I infection
5424,0,0,0,0,0,0,27,0,38,0,0,0,"POLD1;polymerase (DNA directed), delta 1, catalytic subunit",GO:0043625//delta DNA polymerase complex;GO:0016020//membrane;GO:0016235//aggresome;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000109//nucleotide-excision repair complex,"GO:0019985//translesion synthesis;GO:0044281//small molecule metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0043137//DNA replication, removal of RNA primer;GO:0006287//base-excision repair, gap-filling;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0009411//response to UV;GO:0007346//regulation of mitotic cell cycle;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair;GO:0006284//base-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0045004//DNA replication proofreading;GO:0055089//fatty acid homeostasis;GO:0000731//DNA synthesis involved in DNA repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair","GO:0003682//chromatin binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0008408//3'-5' exonuclease activity;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003887//DNA-directed DNA polymerase activity",K02327//Purine metabolism;Metabolic pathways;DNA replication;Pyrimidine metabolism;Mismatch repair;Homologous recombination;Base excision repair;Nucleotide excision repair;HTLV-I infection
5425,0,0,1,1,6,5,0,0,12,97,0,0,"POLD2;polymerase (DNA directed), delta 2, accessory subunit",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043625//delta DNA polymerase complex,"GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair;GO:0000723//telomere maintenance;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0000722//telomere maintenance via recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006284//base-excision repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair",GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0003677//DNA binding,K02328//Purine metabolism;DNA replication;Metabolic pathways;Pyrimidine metabolism;Mismatch repair;Homologous recombination;Base excision repair;Nucleotide excision repair;HTLV-I infection
5426,0,0,0,0,9,42,28,2,83,159,9,0,"POLE;polymerase (DNA directed), epsilon, catalytic subunit",GO:0008622//epsilon DNA polymerase complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005730//nucleolus,"GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0001701//in utero embryonic development;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006287//base-excision repair, gap-filling;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006289//nucleotide-excision repair;GO:0006270//DNA replication initiation;GO:0000731//DNA synthesis involved in DNA repair","GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0000166//nucleotide binding;GO:0003887//DNA-directed DNA polymerase activity",K02324//Pyrimidine metabolism;Base excision repair;Purine metabolism;DNA replication;Metabolic pathways;Nucleotide excision repair;HTLV-I infection
5427,107,0,0,0,0,0,0,0,52,0,0,0,"POLE2;polymerase (DNA directed), epsilon 2, accessory subunit",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0008622//epsilon DNA polymerase complex;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006270//DNA replication initiation;GO:0006289//nucleotide-excision repair;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000082//G1/S transition of mitotic cell cycle",GO:0003677//DNA binding;GO:0003887//DNA-directed DNA polymerase activity,K02325//Purine metabolism;Pyrimidine metabolism;Base excision repair;Nucleotide excision repair;Metabolic pathways;HTLV-I infection;DNA replication
542767,0,0,55,0,0,0,0,0,18,0,8,0,C1QTNF9B-AS1;C1QTNF9B antisense RNA 1,GO:0005737//cytoplasm,-,-,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction;K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus
5428,0,1,59,37,63,28,16,2,47,0,98,0,"POLG;polymerase (DNA directed), gamma",GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005760//gamma DNA polymerase complex,"GO:0006287//base-excision repair, gap-filling;GO:0008219//cell death;GO:0006264//mitochondrial DNA replication;GO:0007568//aging;GO:0006259//DNA metabolic process;GO:0006261//DNA-dependent DNA replication;GO:0090305//nucleic acid phosphodiester bond hydrolysis",GO:0003682//chromatin binding;GO:0002020//protease binding;GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0003887//DNA-directed DNA polymerase activity;GO:0003677//DNA binding,K02332//Metabolic pathways
5429,0,32,34,44,12,52,2,0,48,0,8,0,"POLH;polymerase (DNA directed), eta",GO:0005654//nucleoplasm,GO:0006261//DNA-dependent DNA replication;GO:0010225//response to UV-C;GO:0006290//pyrimidine dimer repair;GO:0006281//DNA repair;GO:0006301//postreplication repair;GO:0006282//regulation of DNA repair;GO:0000731//DNA synthesis involved in DNA repair,GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003684//damaged DNA binding,K03509//Fanconi anemia pathway
5430,161,13,0,30,67,1,76,117,0,1,3,443,"POLR2A;polymerase (RNA) II (DNA directed) polypeptide A, 220kDa","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0016032//viral process;GO:0001172//transcription, RNA-templated;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0006355//regulation of transcription, DNA-templated;GO:0050434//positive regulation of viral transcription",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0003968//RNA-directed RNA polymerase activity;GO:0003899//DNA-directed RNA polymerase activity;GO:0031625//ubiquitin protein ligase binding;GO:0003677//DNA binding;GO:0001055//RNA polymerase II activity,K03006//Huntington's disease;Metabolic pathways;Herpes simplex infection;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism
5431,0,61,1,57,237,11,14,0,72,0,0,0,"POLR2B;polymerase (RNA) II (DNA directed) polypeptide B, 140kDa","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0016020//membrane","GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0050434//positive regulation of viral transcription",GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0032549//ribonucleoside binding;GO:0003682//chromatin binding,K03010//Huntington's disease;Metabolic pathways;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Pyrimidine metabolism
5432,0,87,26,9,63,0,0,1,1,0,9,0,"POLR2C;polymerase (RNA) II (DNA directed) polypeptide C, 33kDa","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton","GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0050434//positive regulation of viral transcription",GO:0046983//protein dimerization activity;GO:0001055//RNA polymerase II activity;GO:0003677//DNA binding,K03011//Huntington's disease;Metabolic pathways;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism
54328,31,0,0,0,0,12,0,0,43,0,0,0,GPR173;G protein-coupled receptor 173,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:2001223//negative regulation of neuron migration,GO:0004968//gonadotropin-releasing hormone receptor activity;GO:0004930//G-protein coupled receptor activity,-
54329,0,0,0,0,0,0,0,0,5,0,0,0,GPR85;G protein-coupled receptor 85,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
5433,4,0,0,0,11,0,0,0,18,0,0,0,POLR2D;polymerase (RNA) II (DNA directed) polypeptide D,"GO:0005654//nucleoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0034402//recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0050434//positive regulation of viral transcription;GO:0016032//viral process;GO:0045948//positive regulation of translational initiation;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome",GO:0003697//single-stranded DNA binding;GO:0000166//nucleotide binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0003727//single-stranded RNA binding;GO:0031369//translation initiation factor binding,K03012//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Huntington's disease;Metabolic pathways
54331,0,0,0,0,17,0,51,0,30,0,0,0,"GNG2;guanine nucleotide binding protein (G protein), gamma 2",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0071870//cellular response to catecholamine stimulus;GO:0030168//platelet activation;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007268//synaptic transmission;GO:0008283//cell proliferation;GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process,GO:0004871//signal transducer activity;GO:0031681//G-protein beta-subunit binding,K07826//Morphine addiction;Glutamatergic synapse;Serotonergic synapse;Alcoholism;Retrograde endocannabinoid signaling;Cholinergic synapse;GABAergic synapse;Dopaminergic synapse;Chemokine signaling pathway
54332,77,0,0,1,10,0,43,0,21,0,0,0,GDAP1;ganglioside induced differentiation associated protein 1,GO:0016020//membrane;GO:0005634//nucleus;GO:0031307//integral component of mitochondrial outer membrane,GO:0000266//mitochondrial fission;GO:0032526//response to retinoic acid;GO:0006626//protein targeting to mitochondrion;GO:0008219//cell death,-,K00799//Pathways in cancer;Drug metabolism - cytochrome P450;Glutathione metabolism;Prostate cancer;Metabolism of xenobiotics by cytochrome P450
5434,24,1,0,10,8,0,0,68,25,0,20,7,"POLR2E;polymerase (RNA) II (DNA directed) polypeptide E, 25kDa","GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005634//nucleus;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005829//cytosol;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0006360//transcription from RNA polymerase I promoter;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0032481//positive regulation of type I interferon production;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0016032//viral process",GO:0003899//DNA-directed RNA polymerase activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0001056//RNA polymerase III activity;GO:0001054//RNA polymerase I activity;GO:0001055//RNA polymerase II activity,K03013//Huntington's disease;Cytosolic DNA-sensing pathway;Metabolic pathways;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism
54344,0,0,0,0,1,0,6,0,0,0,0,0,DPM3;dolichyl-phosphate mannosyltransferase polypeptide 3,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0033185//dolichol-phosphate-mannose synthase complex,GO:0005975//carbohydrate metabolic process;GO:0006506//GPI anchor biosynthetic process;GO:0018406//protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan;GO:0043687//post-translational protein modification;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0035269//protein O-linked mannosylation;GO:0044267//cellular protein metabolic process;GO:0031647//regulation of protein stability;GO:0006501//C-terminal protein lipidation,GO:0004582//dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0005515//protein binding,K09659//Metabolic pathways;N-Glycan biosynthesis
54345,0,0,0,0,0,0,0,14,0,0,0,0,SOX18;SRY (sex determining region Y)-box 18,GO:0044798//nuclear transcription factor complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0048866//stem cell fate specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060214//endocardium formation;GO:0001944//vasculature development;GO:0060836//lymphatic endothelial cell differentiation;GO:0043534//blood vessel endothelial cell migration;GO:0060956//endocardial cell differentiation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0001946//lymphangiogenesis;GO:0035050//embryonic heart tube development;GO:0003151//outflow tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001947//heart looping;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0001942//hair follicle development;GO:0061028//establishment of endothelial barrier;GO:0048469//cell maturation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001570//vasculogenesis;GO:0001525//angiogenesis;GO:0072091//regulation of stem cell proliferation",GO:0046982//protein heterodimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
54346,0,0,0,0,0,18,14,0,0,0,0,0,UNC93A;unc-93 homolog A (C. elegans),GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,-
5436,158,32,1,1,26,0,0,37,10,0,0,0,POLR2G;polymerase (RNA) II (DNA directed) polypeptide G,"GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000398//mRNA splicing, via spliceosome;GO:0006915//apoptotic process;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0045948//positive regulation of translational initiation;GO:0016032//viral process;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000291//nuclear-transcribed mRNA catabolic process, exonucleolytic;GO:0006368//transcription elongation from RNA polymerase II promoter",GO:0003899//DNA-directed RNA polymerase activity;GO:0003697//single-stranded DNA binding;GO:0031369//translation initiation factor binding;GO:0003727//single-stranded RNA binding,K03015//Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Huntington's disease;Metabolic pathways
54360,0,0,0,0,0,0,0,0,30,0,0,0,CYTL1;cytokine-like 1,GO:0005615//extracellular space,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1990079//cartilage homeostasis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0048839//inner ear development;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0007165//signal transduction;GO:0002062//chondrocyte differentiation,GO:0005102//receptor binding,-
54361,0,0,0,0,0,5,0,61,20,0,3,0,"WNT4;wingless-type MMTV integration site family, member 4",GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,"GO:0060126//somatotropin secreting cell differentiation;GO:0008584//male gonad development;GO:0061369//negative regulation of testicular blood vessel morphogenesis;GO:0061184//positive regulation of dermatome development;GO:2000019//negative regulation of male gonad development;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0051145//smooth muscle cell differentiation;GO:0009267//cellular response to starvation;GO:0061205//paramesonephric duct development;GO:0032321//positive regulation of Rho GTPase activity;GO:0033080//immature T cell proliferation in thymus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030336//negative regulation of cell migration;GO:0032967//positive regulation of collagen biosynthetic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0008585//female gonad development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000225//negative regulation of testosterone biosynthetic process;GO:0048599//oocyte development;GO:0001889//liver development;GO:0001822//kidney development;GO:0006702//androgen biosynthetic process;GO:0001838//embryonic epithelial tube formation;GO:0010629//negative regulation of gene expression;GO:0060748//tertiary branching involved in mammary gland duct morphogenesis;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0072174//metanephric tubule formation;GO:0090002//establishment of protein localization to plasma membrane;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0030182//neuron differentiation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0072034//renal vesicle induction;GO:0022407//regulation of cell-cell adhesion;GO:0010894//negative regulation of steroid biosynthetic process;GO:0018345//protein palmitoylation;GO:0051496//positive regulation of stress fiber assembly;GO:0072162//metanephric mesenchymal cell differentiation;GO:0030325//adrenal gland development;GO:0061045//negative regulation of wound healing;GO:0072273//metanephric nephron morphogenesis;GO:0072033//renal vesicle formation;GO:0060070//canonical Wnt signaling pathway;GO:0060231//mesenchymal to epithelial transition;GO:0038030//non-canonical Wnt signaling pathway via MAPK cascade;GO:0045836//positive regulation of meiosis;GO:0061180//mammary gland epithelium development;GO:0051894//positive regulation of focal adhesion assembly;GO:0045669//positive regulation of osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0030237//female sex determination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045165//cell fate commitment;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:2000066//positive regulation of cortisol biosynthetic process",GO:0048018//receptor agonist activity;GO:0003714//transcription corepressor activity;GO:0005109//frizzled binding,K00408//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection
54363,1,0,0,0,0,15,0,43,1,0,0,0,HAO1;hydroxyacid oxidase (glycolate oxidase) 1,GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,GO:0034641//cellular nitrogen compound metabolic process;GO:0046487//glyoxylate metabolic process;GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0001561//fatty acid alpha-oxidation;GO:0046296//glycolate catabolic process,GO:0008891//glycolate oxidase activity;GO:0052852//very-long-chain-(S)-2-hydroxy-acid oxidase activity;GO:0052854//medium-chain-(S)-2-hydroxy-acid oxidase activity;GO:0052853//long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity;GO:0010181//FMN binding;GO:0005102//receptor binding;GO:0047969//glyoxylate oxidase activity,K11517//Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Biosynthesis of secondary metabolites;Peroxisome
5437,0,10,0,0,19,1,0,130,3,0,1,0,POLR2H;polymerase (RNA) II (DNA directed) polypeptide H,"GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005829//cytosol;GO:0005736//DNA-directed RNA polymerase I complex","GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0000398//mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping;GO:0050434//positive regulation of viral transcription;GO:0016032//viral process;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032481//positive regulation of type I interferon production;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter",GO:0001055//RNA polymerase II activity;GO:0001054//RNA polymerase I activity;GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding,K03016//Cytosolic DNA-sensing pathway;Huntington's disease;Metabolic pathways;Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection
5438,0,40,1,7,0,0,35,111,33,0,13,235,"POLR2I;polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa","GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm","GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0001193//maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0006370//7-methylguanosine mRNA capping",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003899//DNA-directed RNA polymerase activity,K03017//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Huntington's disease;Metabolic pathways
54386,0,37,0,100,81,0,0,25,25,0,0,0,"TERF2IP;telomeric repeat binding factor 2, interacting protein","GO:0000784//nuclear chromosome, telomeric region;GO:0030870//Mre11 complex;GO:0000228//nuclear chromosome;GO:0000783//nuclear telomere cap complex;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005634//nucleus","GO:0031848//protection from non-homologous end joining at telomere;GO:0032205//negative regulation of telomere maintenance;GO:0000723//telomere maintenance;GO:0006351//transcription, DNA-templated;GO:0007004//telomere maintenance via telomerase;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048239//negative regulation of DNA recombination at telomere;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0010833//telomere maintenance via telomere lengthening;GO:0070198//protein localization to chromosome, telomeric region",GO:0005515//protein binding;GO:0042162//telomeric DNA binding,-
5439,0,0,0,2,14,0,0,0,25,0,7,0,"POLR2J;polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000398//mRNA splicing, via spliceosome;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process",GO:0005515//protein binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0003677//DNA binding;GO:0001055//RNA polymerase II activity;GO:0030275//LRR domain binding;GO:0046983//protein dimerization activity,K03008//RNA polymerase;Epstein-Barr virus infection;Purine metabolism;Pyrimidine metabolism;Metabolic pathways;Huntington's disease
5440,0,23,0,76,215,0,4,0,14,0,0,0,"POLR2K;polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005829//cytosol;GO:0005736//DNA-directed RNA polymerase I complex","GO:0016032//viral process;GO:0050434//positive regulation of viral transcription;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0006356//regulation of transcription from RNA polymerase I promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0032481//positive regulation of type I interferon production;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006385//transcription elongation from RNA polymerase III promoter",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0001056//RNA polymerase III activity;GO:0001054//RNA polymerase I activity;GO:0001055//RNA polymerase II activity,K03009//Huntington's disease;Cytosolic DNA-sensing pathway;Metabolic pathways;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Pyrimidine metabolism
54407,0,0,0,15,34,40,54,0,0,0,0,0,"SLC38A2;solute carrier family 38, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006814//sodium ion transport;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0014047//glutamate secretion,GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity,K14207//GABAergic synapse;Glutamatergic synapse;Protein digestion and absorption
5441,0,2,0,0,13,0,0,0,2,0,0,0,"POLR2L;polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa","GO:0005829//cytosol;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005665//DNA-directed RNA polymerase II, core complex;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005634//nucleus","GO:0006386//termination of RNA polymerase III transcription;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0032481//positive regulation of type I interferon production;GO:0006360//transcription from RNA polymerase I promoter;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0006370//7-methylguanosine mRNA capping;GO:0006356//regulation of transcription from RNA polymerase I promoter;GO:0006281//DNA repair;GO:0016032//viral process;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000398//mRNA splicing, via spliceosome;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter",GO:0003899//DNA-directed RNA polymerase activity;GO:0001056//RNA polymerase III activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0001055//RNA polymerase II activity;GO:0001054//RNA polymerase I activity,K03007//Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism;Metabolic pathways;Cytosolic DNA-sensing pathway;Huntington's disease
54413,0,0,0,0,0,0,0,37,60,0,9,0,NLGN3;neuroligin 3,GO:0009986//cell surface;GO:0030139//endocytic vesicle;GO:0060076//excitatory synapse;GO:0030054//cell junction;GO:0045202//synapse;GO:0005887//integral component of plasma membrane,"GO:0035176//social behavior;GO:0060080//regulation of inhibitory postsynaptic membrane potential;GO:0006898//receptor-mediated endocytosis;GO:2000969//positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0030534//adult behavior;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0007416//synapse assembly;GO:0048709//oligodendrocyte differentiation;GO:0008542//visual learning;GO:0060024//rhythmic synaptic transmission;GO:0097104//postsynaptic membrane assembly;GO:0050804//regulation of synaptic transmission;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0051965//positive regulation of synapse assembly;GO:1900271//regulation of long-term synaptic potentiation;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:2000331//regulation of terminal button organization;GO:0061001//regulation of dendritic spine morphogenesis;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0048675//axon extension;GO:0097105//presynaptic membrane assembly;GO:0050808//synapse organization;GO:0007612//learning;GO:0007158//neuron cell-cell adhesion;GO:0071625//vocalization behavior",GO:0042043//neurexin family protein binding;GO:0004872//receptor activity;GO:0050839//cell adhesion molecule binding;GO:0005515//protein binding,K07378//Cell adhesion molecules (CAMs)
54414,0,0,0,0,1,0,10,0,20,0,8,0,SIAE;sialic acid acetylesterase,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005764//lysosome,GO:0002682//regulation of immune system process;GO:0005975//carbohydrate metabolic process,GO:0001681//sialate O-acetylesterase activity,-
5442,0,5,0,21,2,0,14,5,32,120,21,418,POLRMT;polymerase (RNA) mitochondrial (DNA directed),GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005759//mitochondrial matrix,GO:0010467//gene expression;GO:0006391//transcription initiation from mitochondrial promoter;GO:0006390//transcription from mitochondrial promoter,GO:0003899//DNA-directed RNA polymerase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
5443,0,0,0,0,0,14,0,0,36,95,0,0,POMC;proopiomelanocortin,GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0005615//extracellular space;GO:0034774//secretory granule lumen;GO:0005737//cytoplasm;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome,GO:2000852//regulation of corticosterone secretion;GO:0044267//cellular protein metabolic process;GO:0032098//regulation of appetite;GO:0008217//regulation of blood pressure;GO:0007218//neuropeptide signaling pathway;GO:0032720//negative regulation of tumor necrosis factor production;GO:0033059//cellular pigmentation;GO:0006091//generation of precursor metabolites and energy;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070873//regulation of glycogen metabolic process;GO:0016486//peptide hormone processing;GO:0042593//glucose homeostasis,GO:0070996//type 1 melanocortin receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0005179//hormone activity;GO:0031781//type 3 melanocortin receptor binding;GO:0001664//G-protein coupled receptor binding;GO:0005102//receptor binding,K05228//Melanogenesis;Adipocytokine signaling pathway
54431,2,0,0,22,7,45,34,0,51,0,0,0,"DNAJC10;DnaJ (Hsp40) homolog, subfamily C, member 10",GO:0034663//endoplasmic reticulum chaperone complex;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0032781//positive regulation of ATPase activity;GO:0034976//response to endoplasmic reticulum stress;GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process;GO:0034975//protein folding in endoplasmic reticulum;GO:0001933//negative regulation of protein phosphorylation,"GO:0051787//misfolded protein binding;GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0015035//protein disulfide oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0030544//Hsp70 protein binding;GO:0051117//ATPase binding;GO:0051087//chaperone binding;GO:0015036//disulfide oxidoreductase activity",K09530//Protein processing in endoplasmic reticulum
54432,0,0,0,43,85,8,0,0,10,0,0,0,"YIPF1;Yip1 domain family, member 1",GO:0016021//integral component of membrane;GO:0030133//transport vesicle,-,-,-
54433,0,0,0,35,27,4,21,0,0,0,0,0,GAR1;GAR1 ribonucleoprotein,GO:0031429//box H/ACA snoRNP complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0015030//Cajal body,GO:0006812//cation transport;GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005261//cation channel activity,K11128//Ribosome biogenesis in eukaryotes
54434,0,0,1,0,22,42,2,0,34,0,7,0,SSH1;slingshot protein phosphatase 1,GO:0005634//nucleus;GO:0030496//midbody;GO:0005730//nucleolus;GO:0030027//lamellipodium;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0032154//cleavage furrow;GO:0005886//plasma membrane,GO:0071318//cellular response to ATP;GO:0050770//regulation of axonogenesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0000902//cell morphogenesis;GO:0032268//regulation of cellular protein metabolic process;GO:0008064//regulation of actin polymerization or depolymerization;GO:0010591//regulation of lamellipodium assembly,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0003677//DNA binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0003779//actin binding,K05766//Regulation of actin cytoskeleton
54435,0,0,0,0,4,0,17,0,0,0,0,0,HCG4;HLA complex group 4 (non-protein coding),-,-,-,K06751//Autoimmune thyroid disease;Phagosome;HTLV-I infection;Endocytosis;Type I diabetes mellitus;Allograft rejection;Graft-versus-host disease;Viral myocarditis;Natural killer cell mediated cytotoxicity;Herpes simplex infection;Cell adhesion molecules (CAMs);Epstein-Barr virus infection;Antigen processing and presentation
54436,64,0,0,0,0,0,37,0,76,0,0,0,SH3TC1;SH3 domain and tetratricopeptide repeats 1,-,-,-,K15839//Cocaine addiction
54437,1,0,0,0,0,23,21,0,66,33,9,272,"SEMA5B;sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B",GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007399//nervous system development,GO:0004872//receptor activity,K06841//Axon guidance
54438,0,0,0,0,0,14,0,0,0,1,0,4,GFOD1;glucose-fructose oxidoreductase domain containing 1,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K00078//Pentose and glucuronate interconversions;Metabolism of xenobiotics by cytochrome P450
54439,39,0,3,19,78,23,32,0,77,0,0,1,RBM27;RNA binding motif protein 27,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005730//nucleolus,GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0000166//nucleotide binding,-
5444,0,42,0,0,0,0,1,0,9,0,0,0,PON1;paraoxonase 1,GO:0034364//high-density lipoprotein particle;GO:0034366//spherical high-density lipoprotein particle;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space,GO:0010875//positive regulation of cholesterol efflux;GO:0046470//phosphatidylcholine metabolic process;GO:0009636//response to toxic substance;GO:0019439//aromatic compound catabolic process;GO:0034445//negative regulation of plasma lipoprotein particle oxidation;GO:0032411//positive regulation of transporter activity;GO:0046395//carboxylic acid catabolic process;GO:0051099//positive regulation of binding;GO:0016311//dephosphorylation;GO:0046434//organophosphate catabolic process;GO:0009605//response to external stimulus,GO:0005509//calcium ion binding;GO:0005543//phospholipid binding;GO:0004064//arylesterase activity;GO:0004063//aryldialkylphosphatase activity;GO:0042803//protein homodimerization activity,K01045//Metabolic pathways
54440,0,0,1,0,22,0,22,0,29,112,0,0,SASH3;SAM and SH3 domain containing 3,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0032760//positive regulation of tumor necrosis factor production;GO:0030890//positive regulation of B cell proliferation;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0042102//positive regulation of T cell proliferation;GO:0032753//positive regulation of interleukin-4 production;GO:0032729//positive regulation of interferon-gamma production;GO:0046622//positive regulation of organ growth;GO:0032743//positive regulation of interleukin-2 production;GO:0002639//positive regulation of immunoglobulin production;GO:0048873//homeostasis of number of cells within a tissue;GO:0032733//positive regulation of interleukin-10 production;GO:0002726//positive regulation of T cell cytokine production",-,K04438//Fc gamma R-mediated phagocytosis;Shigellosis;Chemokine signaling pathway;Pathways in cancer;Bacterial invasion of epithelial cells;Insulin signaling pathway;ErbB signaling pathway;Focal adhesion;Renal cell carcinoma;MAPK signaling pathway;Chronic myeloid leukemia;Neurotrophin signaling pathway;Regulation of actin cytoskeleton
54441,1,1,0,0,0,0,43,0,0,0,2,4,STAG3L1;stromal antigen 3-like 1 (pseudogene),GO:0005634//nucleus,-,-,K13055//Oocyte meiosis
54442,0,0,0,0,14,20,12,52,0,0,0,0,KCTD5;potassium channel tetramerization domain containing 5,GO:0005829//cytosol;GO:0005634//nucleus,GO:0051260//protein homooligomerization;GO:0016032//viral process,GO:0032403//protein complex binding;GO:0005515//protein binding,K04257//Olfactory transduction
54443,0,0,0,0,0,0,62,0,71,0,1,32,"ANLN;anillin, actin binding protein",GO:0005826//actomyosin contractile ring;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0007067//mitotic nuclear division;GO:0007096//regulation of exit from mitosis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0000921//septin ring assembly;GO:0000281//mitotic cytokinesis,GO:0003779//actin binding,K08836//Oocyte meiosis
5445,60,0,0,0,0,0,48,0,0,0,6,0,PON2;paraoxonase 2,GO:0005764//lysosome;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0006979//response to oxidative stress;GO:0019439//aromatic compound catabolic process,GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0004064//arylesterase activity,K01045//Metabolic pathways
54453,0,22,0,0,1,45,0,0,38,0,0,0,RIN2;Ras and Rab interactor 2,GO:0005737//cytoplasm,GO:0032851//positive regulation of Rab GTPase activity;GO:0050790//regulation of catalytic activity;GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction,GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005083//small GTPase regulator activity;GO:0005096//GTPase activator activity,-
54455,218,0,1,18,45,10,19,0,36,0,0,0,FBXO42;F-box protein 42,-,-,-,-
54456,0,0,3,0,0,14,23,0,72,28,13,0,MOV10L1;Mov10 RISC complex RNA helicase like 1,GO:0005622//intracellular,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0006200//ATP catabolic process;GO:0007281//germ cell development,GO:0000287//magnesium ion binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004004//ATP-dependent RNA helicase activity,-
54457,0,0,0,0,0,0,21,0,49,0,1,0,"TAF7L;TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa",GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter",-,K03132//Basal transcription factors
54458,0,0,0,9,32,0,0,0,1,0,0,0,PRR13;proline rich 13,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
54460,0,8,0,1,1,14,0,0,0,0,12,0,MRPS21;mitochondrial ribosomal protein S21,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
54461,75,0,1,0,1,11,18,8,26,0,10,0,FBXW5;F-box and WD repeat domain containing 5,GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0019005//SCF ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0051298//centrosome duplication;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division,GO:0019901//protein kinase binding;GO:0005515//protein binding,-
54462,0,31,0,18,140,38,25,0,9,0,0,0,CCSER2;coiled-coil serine-rich protein 2,GO:0015630//microtubule cytoskeleton,GO:0001578//microtubule bundle formation,GO:0008017//microtubule binding,K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
54463,0,0,0,0,0,40,16,0,11,0,1,0,"FAM134B;family with sequence similarity 134, member B",GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016021//integral component of membrane,GO:0019233//sensory perception of pain,-,-
54464,16,68,0,53,219,23,9,0,84,0,3,0,XRN1;5'-3' exoribonuclease 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0000932//cytoplasmic mRNA processing body,"GO:0071028//nuclear mRNA surveillance;GO:0016075//rRNA catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0071044//histone mRNA catabolic process",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008409//5'-3' exonuclease activity,K12618//Ribosome biogenesis in eukaryotes;RNA degradation
54465,81,0,0,18,13,26,0,0,79,0,0,0,ETAA1;Ewing tumor-associated antigen 1,GO:0005737//cytoplasm,-,-,-
54466,0,0,0,0,0,0,9,0,19,0,0,0,"SPIN2A;spindlin family, member 2A",GO:0005634//nucleus,GO:0007276//gamete generation;GO:0007049//cell cycle;GO:0051726//regulation of cell cycle,-,-
54467,0,12,1,38,126,32,28,0,18,0,16,0,ANKIB1;ankyrin repeat and IBR domain containing 1,-,-,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
54468,0,29,0,88,142,8,0,0,11,0,0,0,"MIOS;missing oocyte, meiosis regulator, homolog (Drosophila)",GO:0005765//lysosomal membrane,-,-,-
54469,0,0,0,10,108,9,14,141,25,0,0,0,"ZFAND6;zinc finger, AN1-type domain 6",GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006625//protein targeting to peroxisome;GO:0043066//negative regulation of apoptotic process;GO:0071356//cellular response to tumor necrosis factor,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0031593//polyubiquitin binding,-
5447,40,0,1,4,9,45,1,3,7,0,0,280,POR;P450 (cytochrome) oxidoreductase,GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0043602//nitrate catabolic process;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0045880//positive regulation of smoothened signaling pathway;GO:0070988//demethylation;GO:0090031//positive regulation of steroid hormone biosynthetic process;GO:0009812//flavonoid metabolic process;GO:0003420//regulation of growth plate cartilage chondrocyte proliferation;GO:0071375//cellular response to peptide hormone stimulus;GO:0060192//negative regulation of lipase activity;GO:0009437//carnitine metabolic process;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0090346//cellular organofluorine metabolic process;GO:0032770//positive regulation of monooxygenase activity;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0043066//negative regulation of apoptotic process;GO:0046210//nitric oxide catabolic process;GO:0042493//response to drug;GO:0019395//fatty acid oxidation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032332//positive regulation of chondrocyte differentiation;GO:0018393//internal peptidyl-lysine acetylation,"GO:0010181//FMN binding;GO:0019899//enzyme binding;GO:0050661//NADP binding;GO:0003958//NADPH-hemoprotein reductase activity;GO:0005506//iron ion binding;GO:0008941//nitric oxide dioxygenase activity;GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0016787//hydrolase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0009055//electron carrier activity;GO:0047726//iron-cytochrome-c reductase activity;GO:0005515//protein binding",-
54470,0,0,0,0,0,8,0,0,0,0,0,0,"ARMCX6;armadillo repeat containing, X-linked 6",GO:0016021//integral component of membrane,-,-,-
54471,16,52,0,13,16,27,9,0,49,0,35,0,MIEF1;mitochondrial elongation factor 1,GO:0005777//peroxisome;GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0090314//positive regulation of protein targeting to membrane;GO:0008053//mitochondrial fusion;GO:0000266//mitochondrial fission;GO:0090141//positive regulation of mitochondrial fission,GO:0043531//ADP binding;GO:0042802//identical protein binding;GO:0019003//GDP binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
54472,0,24,0,9,28,24,5,43,0,0,0,0,TOLLIP;toll interacting protein,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0045092//interleukin-18 receptor complex;GO:0016604//nuclear body;GO:0045323//interleukin-1 receptor complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0007267//cell-cell signaling;GO:0036010//protein localization to endosome;GO:0016310//phosphorylation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0035556//intracellular signal transduction;GO:0045321//leukocyte activation;GO:0030855//epithelial cell differentiation;GO:0033235//positive regulation of protein sumoylation,"GO:0019900//kinase binding;GO:0032183//SUMO binding;GO:0005150//interleukin-1, Type I receptor binding;GO:0035325//Toll-like receptor binding;GO:0005515//protein binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0031625//ubiquitin protein ligase binding;GO:0004871//signal transducer activity",K05402//Toll-like receptor signaling pathway
54474,0,0,0,0,1,25,0,0,33,0,0,0,KRT20;keratin 20,GO:0005882//intermediate filament;GO:0005737//cytoplasm,GO:0045109//intermediate filament organization;GO:0050708//regulation of protein secretion;GO:0033554//cellular response to stress;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
54475,0,0,22,0,0,0,22,0,26,0,0,0,NLE1;notchless homolog 1 (Drosophila),GO:0005730//nucleolus;GO:0005634//nucleus,GO:0045930//negative regulation of mitotic cell cycle;GO:0042273//ribosomal large subunit biogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2001268//negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0007219//Notch signaling pathway;GO:0001826//inner cell mass cell differentiation,-,-
54476,1,1,0,0,45,9,0,0,67,0,0,0,RNF216;ring finger protein 216,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006915//apoptotic process;GO:0016032//viral process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0050691//regulation of defense response to virus by host;GO:0032648//regulation of interferon-beta production,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding,-
54477,70,0,0,19,52,17,0,1,32,275,15,0,"PLEKHA5;pleckstrin homology domain containing, family A member 5",GO:0016020//membrane;GO:0005829//cytosol,GO:0061458//reproductive system development,"GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005545//1-phosphatidylinositol binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0005515//protein binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding",K10591//Ubiquitin mediated proteolysis;Epstein-Barr virus infection;Endocytosis;K05633//Ubiquitin mediated proteolysis;Endocytosis;K14721//Cytosolic DNA-sensing pathway;Pyrimidine metabolism;Epstein-Barr virus infection;RNA polymerase;Purine metabolism;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K06082//Adherens junction;K03426//Nicotinate and nicotinamide metabolism;Peroxisome
54478,0,0,0,0,0,0,18,0,0,0,24,0,"FAM64A;family with sequence similarity 64, member A",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
54480,53,0,0,0,0,0,0,27,18,1,14,0,CHPF2;chondroitin polymerizing factor 2,GO:0032580//Golgi cisterna membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0008376//acetylgalactosaminyltransferase activity;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity,K03419//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
54482,0,2,0,14,34,0,5,0,31,0,0,0,TRMT13;tRNA methyltransferase 13 homolog (S. cerevisiae),-,GO:0008033//tRNA processing;GO:0032259//methylation,GO:0046872//metal ion binding;GO:0008168//methyltransferase activity,-
54487,0,0,1,0,37,0,21,105,19,193,31,0,DGCR8;DGCR8 microprocessor complex subunit,GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0010467//gene expression;GO:0031053//primary miRNA processing,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003725//double-stranded RNA binding,-
5449,14,0,0,0,0,1,0,0,11,0,0,0,POU1F1;POU class 1 homeobox 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051169//nuclear transport;GO:0040018//positive regulation of multicellular organism growth;GO:0030183//B cell differentiation;GO:0001708//cell fate specification;GO:0008284//positive regulation of cell proliferation;GO:0032962//positive regulation of inositol trisphosphate biosynthetic process;GO:0043567//regulation of insulin-like growth factor receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0060133//somatotropin secreting cell development;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008340//determination of adult lifespan",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
54490,0,44,0,0,0,0,0,0,12,144,17,0,"UGT2B28;UDP glucuronosyltransferase 2 family, polypeptide B28",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0008152//metabolic process,GO:0015020//glucuronosyltransferase activity,K00699//Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Pentose and glucuronate interconversions;Metabolic pathways;Drug metabolism - cytochrome P450;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism
54491,0,0,0,0,1,0,0,0,20,0,0,165,"FAM105A;family with sequence similarity 105, member A",-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
54492,0,0,0,0,0,20,13,71,20,0,11,1,NEURL1B;neuralized E3 ubiquitin protein ligase 1B,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
54494,0,0,0,2,48,0,1,0,25,0,31,0,C11orf71;chromosome 11 open reading frame 71,-,-,-,-
54495,0,0,0,0,18,24,0,0,21,0,0,0,TMX3;thioredoxin-related transmembrane protein 3,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0006457//protein folding,GO:0003756//protein disulfide isomerase activity,-
54496,0,0,0,1,0,14,0,0,43,0,13,0,PRMT7;protein arginine methyltransferase 7,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus,"GO:0034969//histone arginine methylation;GO:0006351//transcription, DNA-templated;GO:0000387//spliceosomal snRNP assembly;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0043985//histone H4-R3 methylation;GO:0030154//cell differentiation;GO:0043393//regulation of protein binding;GO:0019918//peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0016571//histone methylation;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006355//regulation of transcription, DNA-templated;GO:0043046//DNA methylation involved in gamete generation",GO:0016277//[myelin basic protein]-arginine N-methyltransferase activity;GO:0042393//histone binding;GO:0043021//ribonucleoprotein complex binding;GO:0035243//protein-arginine omega-N symmetric methyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0008469//histone-arginine N-methyltransferase activity;GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity,-
54497,0,0,0,9,87,55,1,0,72,0,4,0,HEATR5B;HEAT repeat containing 5B,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,-,-,-
54498,0,0,0,0,13,0,18,101,43,0,0,0,SMOX;spermine oxidase,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006595//polyamine metabolic process;GO:0055114//oxidation-reduction process;GO:0046208//spermine catabolic process;GO:0006596//polyamine biosynthetic process,GO:0052895//N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity;GO:0052901//spermine:oxygen oxidoreductase (spermidine-forming) activity;GO:0052894//norspermine:oxygen oxidoreductase activity;GO:0046592//polyamine oxidase activity,-
54499,0,0,0,1,11,0,0,0,11,159,0,0,TMCO1;transmembrane and coiled-coil domains 1,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,-,-,-
545,96,0,0,10,10,15,2,0,44,0,8,0,ATR;ATR serine/threonine kinase,GO:0005694//chromosome;GO:0016605//PML body;GO:0001741//XY body;GO:0005654//nucleoplasm,"GO:0042493//response to drug;GO:0043393//regulation of protein binding;GO:0000077//DNA damage checkpoint;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0008156//negative regulation of DNA replication;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0007049//cell cycle;GO:0034644//cellular response to UV;GO:0090399//replicative senescence;GO:0071480//cellular response to gamma radiation;GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0006260//DNA replication;GO:0007275//multicellular organismal development",GO:0032407//MutSalpha complex binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0032405//MutLalpha complex binding;GO:0004674//protein serine/threonine kinase activity;GO:0003677//DNA binding;GO:0005524//ATP binding,K06640//HTLV-I infection;Cell cycle;Fanconi anemia pathway;p53 signaling pathway
5450,0,0,0,0,0,0,0,0,10,0,0,0,POU2AF1;POU class 2 associating factor 1,GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006959//humoral immune response;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity;GO:0003713//transcription coactivator activity,K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
54502,0,363,6,296,713,0,0,60,24,0,0,0,RBM47;RNA binding motif protein 47,GO:0005634//nucleus,GO:0002244//hematopoietic progenitor cell differentiation,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
54503,80,0,0,0,0,0,0,0,44,0,0,0,"ZDHHC13;zinc finger, DHHC-type containing 13",GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0030660//Golgi-associated vesicle membrane,GO:0007165//signal transduction;GO:0008152//metabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity;GO:0016409//palmitoyltransferase activity;GO:0004871//signal transducer activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K12460//Neurotrophin signaling pathway
54504,0,0,0,0,0,7,0,0,36,0,0,0,"CPVL;carboxypeptidase, vitellogenic-like",GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0004185//serine-type carboxypeptidase activity,-
54505,0,5,107,51,68,27,117,4,41,0,0,0,DHX29;DEAH (Asp-Glu-Ala-His) box polypeptide 29,GO:0016282//eukaryotic 43S preinitiation complex;GO:0005739//mitochondrion,GO:0006200//ATP catabolic process;GO:0006413//translational initiation,GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0043024//ribosomal small subunit binding;GO:0005524//ATP binding;GO:0003743//translation initiation factor activity,K14442//RNA degradation
54507,45,0,0,0,0,60,10,58,7,0,19,0,ADAMTSL4;ADAMTS-like 4,GO:0005614//interstitial matrix,GO:0043065//positive regulation of apoptotic process;GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0002020//protease binding;GO:0004222//metalloendopeptidase activity,-
54508,0,62,176,43,45,0,0,193,14,0,50,227,EPB41L4A-AS2;EPB41L4A antisense RNA 2 (head to head),-,-,-,-
54509,33,23,0,11,0,0,0,93,2,0,8,0,RHOF;ras homolog family member F (in filopodia),GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007015//actin filament organization,GO:0005525//GTP binding;GO:0003924//GTPase activity,-
5451,16,0,1,28,34,8,0,0,22,0,6,0,POU2F1;POU class 2 homeobox 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter;GO:0010467//gene expression",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09364//Herpes simplex infection
54511,0,0,0,0,0,22,0,0,0,216,0,0,HMGCLL1;3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1,GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,GO:0046951//ketone body biosynthetic process,GO:0004419//hydroxymethylglutaryl-CoA lyase activity;GO:0046872//metal ion binding,"K01640//Biosynthesis of secondary metabolites;Geraniol degradation;Peroxisome;Synthesis and degradation of ketone bodies;Butanoate metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation"
54512,0,84,0,0,15,0,0,136,0,0,44,0,EXOSC4;exosome component 4,GO:0005737//cytoplasm;GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0035327//transcriptionally active chromatin;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0071044//histone mRNA catabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000460//maturation of 5.8S rRNA;GO:0010467//gene expression;GO:0030307//positive regulation of cell growth;GO:0045006//DNA deamination;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0051607//defense response to virus;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0071028//nuclear mRNA surveillance;GO:0006364//rRNA processing",GO:0000175//3'-5'-exoribonuclease activity;GO:0005515//protein binding;GO:0004532//exoribonuclease activity;GO:0017091//AU-rich element binding,K11600//RNA degradation
54514,0,0,0,0,0,0,69,2,1,202,2,289,DDX4;DEAD (Asp-Glu-Ala-Asp) box polypeptide 4,GO:0071547//piP-body;GO:0033391//chromatoid body;GO:0071546//pi-body;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0032880//regulation of protein localization;GO:0007141//male meiosis I;GO:0007283//spermatogenesis;GO:0030317//sperm motility;GO:0006200//ATP catabolic process;GO:0007275//multicellular organismal development,GO:0008026//ATP-dependent helicase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding,-
54516,0,0,0,5,17,0,0,0,0,0,0,0,MTRF1L;mitochondrial translational release factor 1-like,GO:0005739//mitochondrion,GO:0006415//translational termination,"GO:0016149//translation release factor activity, codon specific",-
54517,0,27,0,0,2,10,0,73,30,0,0,0,PUS7;pseudouridylate synthase 7 (putative),-,GO:0008033//tRNA processing;GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0019899//enzyme binding;GO:0044822//poly(A) RNA binding,-
54518,0,0,0,0,0,5,41,0,34,0,0,0,"APBB1IP;amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein",GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0007165//signal transduction,-,-
5452,41,0,0,0,0,0,27,55,5,77,4,2,POU2F2;POU class 2 homeobox 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0048469//cell maturation;GO:0002380//immunoglobulin secretion involved in immune response;GO:0006959//humoral immune response;GO:0006366//transcription from RNA polymerase II promoter;GO:0002335//mature B cell differentiation",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019904//protein domain specific binding,K09364//Herpes simplex infection
54520,11,0,1,0,20,37,28,0,134,0,5,0,CCDC93;coiled-coil domain containing 93,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K04648//Huntington's disease;Vasopressin-regulated water reabsorption;K12478//Endocytosis;Phagosome;Tuberculosis
54521,0,0,0,0,34,12,0,62,38,0,0,0,WDR44;WD repeat domain 44,GO:0005794//Golgi apparatus;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,-,-,K12857//Spliceosome
54522,57,0,0,0,0,13,0,50,1,0,0,0,ANKRD16;ankyrin repeat domain 16,-,-,-,-
54529,60,32,0,36,88,0,0,0,30,0,0,0,ASNSD1;asparagine synthetase domain containing 1,-,GO:0006541//glutamine metabolic process;GO:0006529//asparagine biosynthetic process,GO:0004066//asparagine synthase (glutamine-hydrolyzing) activity,-
5453,0,0,0,0,0,0,25,0,0,0,0,0,POU3F1;POU class 3 homeobox 1,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008366//axon ensheathment;GO:0030216//keratinocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0030900//forebrain development;GO:0022011//myelination in peripheral nervous system;GO:0010628//positive regulation of gene expression",GO:0043565//sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
54531,0,0,0,0,1,0,10,0,57,0,9,0,"MIER2;mesoderm induction early response 1, family member 2",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003682//chromatin binding,-
54532,0,0,0,9,24,16,68,56,93,66,17,0,USP53;ubiquitin specific peptidase 53,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004221//ubiquitin thiolesterase activity,K14206//Protein digestion and absorption
54534,0,0,0,5,1,13,0,0,0,0,0,0,MRPL50;mitochondrial ribosomal protein L50,GO:0005739//mitochondrion;GO:0005840//ribosome,-,-,-
54535,2,0,0,0,0,0,1,63,14,244,0,0,CCHCR1;coiled-coil alpha-helical rod protein 1,GO:0005814//centriole;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0006611//protein export from nucleus;GO:0030154//cell differentiation,-,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis
54536,0,19,1,0,49,11,1,0,64,0,0,0,EXOC6;exocyst complex component 6,GO:0000145//exocyst;GO:0005886//plasma membrane,GO:0044267//cellular protein metabolic process;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0030218//erythrocyte differentiation;GO:0006904//vesicle docking involved in exocytosis,-,-
54537,0,40,0,57,99,10,0,0,46,0,9,0,"FAM35A;family with sequence similarity 35, member A",-,-,-,-
54538,7,0,0,0,0,0,0,0,0,0,0,0,"ROBO4;roundabout, axon guidance receptor, homolog 4 (Drosophila)",GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0030334//regulation of cell migration;GO:0001525//angiogenesis;GO:0030336//negative regulation of cell migration;GO:0030154//cell differentiation,GO:0004872//receptor activity,-
54539,0,27,0,0,1,17,10,59,16,0,21,0,"NDUFB11;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa",GO:0005747//mitochondrial respiratory chain complex I;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,-,K11351//Metabolic pathways;Alzheimer's disease;Huntington's disease;Parkinson's disease;Oxidative phosphorylation
5454,0,0,0,0,0,15,19,0,8,0,10,0,POU3F2;POU class 3 homeobox 2,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0040018//positive regulation of multicellular organism growth;GO:0014002//astrocyte development;GO:0021985//neurohypophysis development;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0008544//epidermis development;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0021979//hypothalamus cell differentiation;GO:0071310//cellular response to organic substance;GO:0050770//regulation of axonogenesis;GO:0022011//myelination in peripheral nervous system",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity,-
54540,0,18,0,4,11,16,0,0,38,0,0,0,"FAM193B;family with sequence similarity 193, member B",GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
54541,63,1,0,13,19,0,0,0,17,0,0,1,DDIT4;DNA-damage-inducible transcript 4,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005622//intracellular;GO:0005737//cytoplasm,GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0043241//protein complex disassembly;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0051607//defense response to virus;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:1901216//positive regulation of neuron death;GO:0072593//reactive oxygen species metabolic process;GO:0032007//negative regulation of TOR signaling;GO:0001764//neuron migration;GO:0030182//neuron differentiation;GO:0008283//cell proliferation;GO:0001666//response to hypoxia;GO:0007420//brain development;GO:0045820//negative regulation of glycolytic process,GO:0071889//14-3-3 protein binding,K08270//mTOR signaling pathway
54542,0,35,1,25,53,6,0,0,17,0,0,0,RC3H2;ring finger and CCCH-type domains 2,GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016020//membrane;GO:0009986//cell surface,GO:0009791//post-embryonic development;GO:0048536//spleen development;GO:0043029//T cell homeostasis;GO:0048286//lung alveolus development;GO:0042098//T cell proliferation;GO:0060173//limb development;GO:0001782//B cell homeostasis;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0048535//lymph node development;GO:0010608//posttranscriptional regulation of gene expression;GO:0035264//multicellular organism growth;GO:0000209//protein polyubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003729//mRNA binding,-
54543,0,18,1,20,65,0,0,0,12,0,0,191,TOMM7;translocase of outer mitochondrial membrane 7 homolog (yeast),GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005742//mitochondrial outer membrane translocase complex,GO:0006626//protein targeting to mitochondrion;GO:0030150//protein import into mitochondrial matrix;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0008320//protein transmembrane transporter activity,-
54545,0,12,1,18,162,42,0,0,0,0,9,0,MTMR12;myotubularin related protein 12,GO:0005737//cytoplasm,GO:0016311//dephosphorylation,GO:0016791//phosphatase activity;GO:0005515//protein binding,K01108//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system;K01112//Fructose and mannose metabolism
54546,0,0,0,0,0,1,0,0,0,0,0,0,RNF186;ring finger protein 186,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
54549,88,0,0,0,0,41,22,1,116,258,11,361,SDK2;sidekick cell adhesion molecule 2,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,K06252//ECM-receptor interaction;Focal adhesion
5455,0,0,0,0,0,0,24,0,0,0,0,0,POU3F3;POU class 3 homeobox 3,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0072233//metanephric thick ascending limb development;GO:0072236//metanephric loop of Henle development;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0007417//central nervous system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0072218//metanephric ascending thin limb development;GO:0021799//cerebral cortex radially oriented cell migration;GO:0021869//forebrain ventricular zone progenitor cell division",GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
54550,0,0,0,0,0,0,0,0,47,0,9,0,NECAB2;N-terminal EF-hand calcium binding protein 2,GO:0005737//cytoplasm,-,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
54551,0,0,2,0,0,10,22,0,42,0,6,0,MAGEL2;MAGE-like 2,GO:0030904//retromer complex;GO:0005768//endosome;GO:0005769//early endosome,"GO:0042147//retrograde transport, endosome to Golgi;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0070534//protein K63-linked ubiquitination",GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K12464//Neurotrophin signaling pathway
54552,267,0,1,0,108,20,42,59,30,0,21,0,GNL3L;guanine nucleotide binding protein-like 3 (nucleolar)-like,GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006184//GTP catabolic process;GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K14538//Ribosome biogenesis in eukaryotes
54554,0,11,0,36,147,8,22,0,5,0,48,0,WDR5B;WD repeat domain 5B,-,-,-,-
54555,118,0,0,1,0,0,0,0,17,0,0,0,DDX49;DEAD (Asp-Glu-Ala-Asp) box polypeptide 49,-,GO:0006200//ATP catabolic process,GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
54556,0,15,0,0,12,0,10,0,0,0,8,0,"ING3;inhibitor of growth family, member 3",GO:0005730//nucleolus;GO:0032777//Piccolo NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0000812//Swr1 complex,"GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0043065//positive regulation of apoptotic process",GO:0035064//methylated histone binding;GO:0008270//zinc ion binding;GO:0004402//histone acetyltransferase activity,-
54557,0,0,0,3,17,0,0,0,9,0,6,0,"SGTB;small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta",-,-,-,K09553//Prion diseases
54558,0,11,0,8,0,37,0,0,42,0,0,139,SPATA6;spermatogenesis associated 6,GO:0005576//extracellular region,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,-,-
5456,0,35,0,0,0,0,0,29,34,0,0,0,POU3F4;POU class 3 homeobox 4,GO:0005634//nucleus,"GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0090103//cochlea morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0007605//sensory perception of sound;GO:0021879//forebrain neuron differentiation",GO:0003680//AT DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding,-
54566,0,3,1,16,76,38,57,0,70,1,0,0,EPB41L4B;erythrocyte membrane protein band 4.1 like 4B,GO:0005856//cytoskeleton;GO:0019898//extrinsic component of membrane;GO:0005737//cytoplasm;GO:0045177//apical part of cell,GO:0031032//actomyosin structure organization,GO:0005200//structural constituent of cytoskeleton;GO:0008092//cytoskeletal protein binding,K06107//Tight junction
54567,0,0,0,0,0,36,18,0,48,112,17,0,DLL4;delta-like 4 (Drosophila),GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0003208//cardiac ventricle morphogenesis;GO:0007165//signal transduction;GO:0007601//visual perception;GO:0008015//blood circulation;GO:0060579//ventral spinal cord interneuron fate commitment;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0007219//Notch signaling pathway;GO:0001569//patterning of blood vessels;GO:0035912//dorsal aorta morphogenesis;GO:0003344//pericardium morphogenesis;GO:0010596//negative regulation of endothelial cell migration;GO:0061074//regulation of neural retina development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0050767//regulation of neurogenesis;GO:0003209//cardiac atrium morphogenesis;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0061314//Notch signaling involved in heart development;GO:0001974//blood vessel remodeling;GO:0001525//angiogenesis;GO:0008285//negative regulation of cell proliferation;GO:0007220//Notch receptor processing;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0072554//blood vessel lumenization,GO:0005509//calcium ion binding;GO:0005112//Notch binding,K06051//Notch signaling pathway
5457,0,0,0,0,0,0,0,6,10,0,0,0,POU4F1;POU class 4 homeobox 1,GO:0043005//neuron projection;GO:0000790//nuclear chromatin,GO:0021986//habenula development;GO:0003223//ventricular compact myocardium morphogenesis;GO:0001967//suckling behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007416//synapse assembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0021535//cell migration in hindbrain;GO:0043065//positive regulation of apoptotic process;GO:0021559//trigeminal nerve development;GO:0060384//innervation;GO:0006366//transcription from RNA polymerase II promoter;GO:0050767//regulation of neurogenesis;GO:0048880//sensory system development;GO:0007409//axonogenesis;GO:0048665//neuron fate specification;GO:0051355//proprioception involved in equilibrioception;GO:0007498//mesoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021953//central nervous system neuron differentiation;GO:0048935//peripheral nervous system neuron development,GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
54575,0,0,0,0,0,0,0,0,8,0,0,0,"UGT1A10;UDP glucuronosyltransferase 1 family, polypeptide A10",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0051552//flavone metabolic process;GO:0052695//cellular glucuronidation,GO:0019899//enzyme binding;GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005080//protein kinase C binding,K00699//Retinol metabolism;Bile secretion;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Pentose and glucuronate interconversions;Metabolic pathways;Drug metabolism - cytochrome P450;Starch and sucrose metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis;Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism
54576,0,0,0,0,0,0,0,0,10,0,0,0,"UGT1A8;UDP glucuronosyltransferase 1 family, polypeptide A8",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle,GO:0045939//negative regulation of steroid metabolic process;GO:0031324//negative regulation of cellular metabolic process;GO:0051552//flavone metabolic process;GO:0042573//retinoic acid metabolic process;GO:2001030//negative regulation of cellular glucuronidation;GO:0045922//negative regulation of fatty acid metabolic process;GO:0052696//flavonoid glucuronidation;GO:0009804//coumarin metabolic process;GO:0006631//fatty acid metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0043086//negative regulation of catalytic activity;GO:0017144//drug metabolic process;GO:0008202//steroid metabolic process,GO:0001972//retinoic acid binding;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0005504//fatty acid binding;GO:0004857//enzyme inhibitor activity;GO:0005496//steroid binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K00699//Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis;Starch and sucrose metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions;Bile secretion;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis
54577,0,0,0,0,0,0,14,0,5,0,0,0,"UGT1A7;UDP glucuronosyltransferase 1 family, polypeptide A7",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0009804//coumarin metabolic process;GO:0052696//flavonoid glucuronidation;GO:0017144//drug metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0007588//excretion;GO:0052697//xenobiotic glucuronidation;GO:0052695//cellular glucuronidation;GO:2001030//negative regulation of cellular glucuronidation;GO:0042573//retinoic acid metabolic process;GO:0051552//flavone metabolic process;GO:0045922//negative regulation of fatty acid metabolic process,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004857//enzyme inhibitor activity;GO:0005080//protein kinase C binding;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0001972//retinoic acid binding,K00699//Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis;Starch and sucrose metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions;Bile secretion;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis
54578,0,0,0,0,0,9,0,0,1,0,0,0,"UGT1A6;UDP glucuronosyltransferase 1 family, polypeptide A6",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:0044281//small molecule metabolic process,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0001972//retinoic acid binding;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding,K00699//Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis;Retinol metabolism;Bile secretion
54579,0,0,0,0,0,0,0,0,29,0,0,0,"UGT1A5;UDP glucuronosyltransferase 1 family, polypeptide A5",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0008152//metabolic process,GO:0015020//glucuronosyltransferase activity,K00699//Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Pentose and glucuronate interconversions;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion
5458,0,0,0,0,0,29,24,24,0,0,1,0,POU4F2;POU class 4 homeobox 2,GO:0005634//nucleus;GO:0016607//nuclear speck,"GO:0030182//neuron differentiation;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0048675//axon extension;GO:0000165//MAPK cascade;GO:0045597//positive regulation of cell differentiation;GO:0006351//transcription, DNA-templated;GO:0050885//neuromuscular process controlling balance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0007605//sensory perception of sound;GO:0060041//retina development in camera-type eye;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031290//retinal ganglion cell axon guidance",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
54581,88,47,4,39,41,0,0,0,39,0,51,0,SCAND2P;SCAN domain containing 2 pseudogene,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity,K09592//Renal cell carcinoma;Pathways in cancer
54583,0,26,52,2,34,14,51,0,60,0,0,0,EGLN1;egl-9 family hypoxia-inducible factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0001666//response to hypoxia;GO:0060711//labyrinthine layer development;GO:0055114//oxidation-reduction process;GO:0055008//cardiac muscle tissue morphogenesis;GO:0060347//heart trabecula formation;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0032364//oxygen homeostasis;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline;GO:0060412//ventricular septum morphogenesis;GO:0071731//response to nitric oxide;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0030821//negative regulation of cAMP catabolic process;GO:0045765//regulation of angiogenesis;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia,GO:0031418//L-ascorbic acid binding;GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0005506//iron ion binding,K09592//Renal cell carcinoma;Pathways in cancer
54584,0,0,0,0,0,0,0,0,15,0,0,0,"GNB1L;guanine nucleotide binding protein (G protein), beta polypeptide 1-like",GO:0009898//cytoplasmic side of plasma membrane;GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035176//social behavior,-,-
54585,0,0,0,4,6,59,0,0,35,0,0,0,LZTFL1;leucine zipper transcription factor-like 1,GO:0005737//cytoplasm;GO:0034464//BBSome,GO:0072594//establishment of protein localization to organelle,GO:0005515//protein binding;GO:0042802//identical protein binding,K04514//Axon guidance;Chemokine signaling pathway;Salmonella infection;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Focal adhesion;K12478//Endocytosis;Phagosome;Tuberculosis;K09291//Thyroid cancer;RNA transport;Pathways in cancer;MAPK signaling pathway - yeast;K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K06638//Cell cycle;Progesterone-mediated oocyte maturation
54586,47,0,0,0,0,1,0,0,6,0,0,0,"EQTN;equatorin, sperm acrosome associated",GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0002079//inner acrosomal membrane;GO:0016021//integral component of membrane;GO:0002081//outer acrosomal membrane;GO:0005634//nucleus,GO:0007342//fusion of sperm to egg plasma membrane;GO:0060478//acrosomal vesicle exocytosis;GO:0006897//endocytosis,-,-
54587,0,0,0,35,27,0,0,41,33,106,52,0,MXRA8;matrix-remodelling associated 8,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0060857//establishment of glial blood-brain barrier,-,-
5459,0,0,0,0,0,0,0,28,0,0,1,0,POU4F3;POU class 4 homeobox 3,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0050885//neuromuscular process controlling balance;GO:0048675//axon extension;GO:0051402//neuron apoptotic process;GO:0031290//retinal ganglion cell axon guidance;GO:0007601//visual perception;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007605//sensory perception of sound;GO:0042491//auditory receptor cell differentiation;GO:0042472//inner ear morphogenesis;GO:0021562//vestibulocochlear nerve development,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
54596,0,0,0,0,1,0,41,0,0,0,0,0,L1TD1;LINE-1 type transposase domain containing 1,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K11447//Transcriptional misregulation in cancer
546,0,61,0,101,376,29,123,7,113,16,1,0,ATRX;alpha thalassemia/mental retardation syndrome X-linked,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016605//PML body;GO:0005730//nucleolus;GO:0031933//telomeric heterochromatin;GO:0005737//cytoplasm;GO:0070603//SWI/SNF superfamily-type complex;GO:0005720//nuclear heterochromatin,"GO:1901581//negative regulation of telomeric RNA transcription from RNA pol II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0031297//replication fork processing;GO:0060009//Sertoli cell development;GO:0006334//nucleosome assembly;GO:0032206//positive regulation of telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0072520//seminiferous tubule development;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0030900//forebrain development;GO:0006351//transcription, DNA-templated;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006310//DNA recombination;GO:0006306//DNA methylation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0072711//cellular response to hydroxyurea;GO:0006338//chromatin remodeling",GO:0070087//chromo shadow domain binding;GO:0008270//zinc ion binding;GO:0015616//DNA translocase activity;GO:0005515//protein binding;GO:0042393//histone binding;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0035064//methylated histone binding;GO:0003678//DNA helicase activity,-
5460,0,0,0,0,0,0,3,0,0,0,0,0,POU5F1;POU class 5 homeobox 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060965//negative regulation of gene silencing by miRNA;GO:0006355//regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0035413//positive regulation of catenin import into nucleus;GO:0001824//blastocyst development;GO:0060913//cardiac cell fate determination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0090308//regulation of methylation-dependent chromatin silencing;GO:0035019//somatic stem cell maintenance;GO:0009611//response to wounding;GO:0009786//regulation of asymmetric cell division;GO:0090081//regulation of heart induction by regulation of canonical Wnt signaling pathway;GO:0001714//endodermal cell fate specification;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0003130//BMP signaling pathway involved in heart induction",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0035198//miRNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
54600,0,0,0,0,1,0,10,0,39,0,0,0,"UGT1A9;UDP glucuronosyltransferase 1 family, polypeptide A9",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0044255//cellular lipid metabolic process;GO:0045922//negative regulation of fatty acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:2001030//negative regulation of cellular glucuronidation;GO:0044281//small molecule metabolic process;GO:0042573//retinoic acid metabolic process;GO:0051552//flavone metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0017144//drug metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0008152//metabolic process;GO:0052696//flavonoid glucuronidation,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0001972//retinoic acid binding;GO:0004857//enzyme inhibitor activity;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding,K00699//Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions;Starch and sucrose metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism
54602,64,0,29,0,0,30,18,0,0,0,0,0,NDFIP2;Nedd4 family interacting protein 2,GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0032585//multivesicular body membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle,GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0032410//negative regulation of transporter activity;GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031398//positive regulation of protein ubiquitination,GO:0050699//WW domain binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,-
54606,67,1,0,0,7,0,0,32,32,0,21,0,DDX56;DEAD (Asp-Glu-Ala-Asp) box helicase 56,GO:0016020//membrane;GO:0005730//nucleolus,GO:0006364//rRNA processing;GO:0006200//ATP catabolic process,GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
54617,34,34,1,5,53,6,22,15,17,0,0,0,INO80;INO80 complex subunit,GO:0031011//Ino80 complex;GO:0005634//nucleus;GO:0005874//microtubule,GO:0030307//positive regulation of cell growth;GO:0000070//mitotic sister chromatid segregation;GO:0006338//chromatin remodeling;GO:0034644//cellular response to UV;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0070914//UV-damage excision repair;GO:0000724//double-strand break repair via homologous recombination;GO:0032508//DNA duplex unwinding;GO:0051225//spindle assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071479//cellular response to ionizing radiation;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0006200//ATP catabolic process;GO:0006302//double-strand break repair,GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003678//DNA helicase activity;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0016887//ATPase activity,-
54619,0,0,0,0,16,0,18,0,39,0,14,0,CCNJ;cyclin J,GO:0005634//nucleus,-,-,K06627//Cell cycle;Epstein-Barr virus infection;Progesterone-mediated oocyte maturation;Transcriptional misregulation in cancer;Acute myeloid leukemia;Pathways in cancer
5462,0,0,0,0,0,0,0,58,23,0,0,0,POU5F1B;POU class 5 homeobox 1B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
54620,0,0,0,0,0,57,0,0,41,0,15,0,FBXL19;F-box and leucine-rich repeat protein 19,GO:0019005//SCF ubiquitin ligase complex,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
54621,0,0,0,12,0,12,1,60,5,2,0,0,VSIG10;V-set and immunoglobulin domain containing 10,GO:0016021//integral component of membrane,-,-,-
54622,63,0,0,9,35,18,0,0,12,0,19,0,ARL15;ADP-ribosylation factor-like 15,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,K07941//Fc gamma R-mediated phagocytosis;Endocytosis
54623,0,0,1,13,37,0,0,240,20,0,3,0,"PAF1;Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)",GO:0016593//Cdc73/Paf1 complex,"GO:0033523//histone H2B ubiquitination;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0010390//histone monoubiquitination;GO:0006351//transcription, DNA-templated;GO:0006378//mRNA polyadenylation;GO:0019827//stem cell maintenance;GO:0001711//endodermal cell fate commitment;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0016055//Wnt signaling pathway",GO:0000993//RNA polymerase II core binding;GO:0003682//chromatin binding;GO:0005515//protein binding,-
54625,0,33,2,55,270,15,1,0,37,40,15,0,"PARP14;poly (ADP-ribose) polymerase family, member 14",GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003950//NAD+ ADP-ribosyltransferase activity,-
54626,0,0,0,0,0,14,0,1,25,0,0,0,HES2;hes family bHLH transcription factor 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003690//double-stranded DNA binding;GO:0008134//transcription factor binding,-
54627,0,0,0,0,0,0,20,0,51,0,45,0,MAP10;microtubule-associated protein 10,GO:0030496//midbody;GO:0097431//mitotic spindle pole;GO:0005881//cytoplasmic microtubule;GO:0005813//centrosome;GO:1990023//mitotic spindle midzone,GO:0032467//positive regulation of cytokinesis;GO:0051256//spindle midzone assembly involved in mitosis;GO:0032886//regulation of microtubule-based process;GO:0031122//cytoplasmic microtubule organization,GO:0008017//microtubule binding,-
54629,2,0,0,13,127,0,34,0,11,0,4,0,"FAM63B;family with sequence similarity 63, member B",-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
5463,0,1,0,4,18,5,0,44,6,0,0,0,POU6F1;POU class 6 homeobox 1,GO:0005634//nucleus,"GO:0007507//heart development;GO:0007517//muscle organ development;GO:0007420//brain development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
5464,0,0,1,6,19,0,16,44,20,0,3,0,PPA1;pyrophosphatase (inorganic) 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0071344//diphosphate metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0004427//inorganic diphosphatase activity;GO:0000287//magnesium ion binding,K01507//Oxidative phosphorylation
5465,0,31,0,26,48,0,34,44,29,246,12,90,PPARA;peroxisome proliferator-activated receptor alpha,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0032868//response to insulin;GO:0044281//small molecule metabolic process;GO:0035095//behavioral response to nicotine;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006631//fatty acid metabolic process;GO:0032922//circadian regulation of gene expression;GO:0008544//epidermis development;GO:0042060//wound healing;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0010891//negative regulation of sequestering of triglyceride;GO:0032099//negative regulation of appetite;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0045776//negative regulation of blood pressure;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042157//lipoprotein metabolic process;GO:0045722//positive regulation of gluconeogenesis;GO:0046321//positive regulation of fatty acid oxidation;GO:0015908//fatty acid transport;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0001666//response to hypoxia;GO:0007507//heart development;GO:0070166//enamel mineralization;GO:0006629//lipid metabolic process;GO:0072369//regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0032091//negative regulation of protein binding;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:1901215//negative regulation of neuron death;GO:0010887//negative regulation of cholesterol storage;GO:0072363//regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter;GO:0010871//negative regulation of receptor biosynthetic process;GO:0030522//intracellular receptor signaling pathway;GO:0072366//regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter;GO:0045820//negative regulation of glycolytic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0042752//regulation of circadian rhythm",GO:0051525//NFAT protein binding;GO:0019904//protein domain specific binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0003677//DNA binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019902//phosphatase binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008144//drug binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0008289//lipid binding;GO:0032403//protein complex binding;GO:0043565//sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003707//steroid hormone receptor activity,K07294//Hepatitis C;PPAR signaling pathway;Adipocytokine signaling pathway
54657,0,0,0,0,0,9,0,0,0,0,0,0,"UGT1A4;UDP glucuronosyltransferase 1 family, polypeptide A4",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0052695//cellular glucuronidation;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding;GO:0001972//retinoic acid binding,K00699//Metabolic pathways;Pentose and glucuronate interconversions;Drug metabolism - cytochrome P450;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism
54658,0,0,0,0,0,14,0,0,0,0,0,0,"UGT1A1;UDP glucuronosyltransferase 1 family, polypeptide A1",GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0070069//cytochrome complex;GO:0005783//endoplasmic reticulum,GO:0008210//estrogen metabolic process;GO:0042167//heme catabolic process;GO:0007584//response to nutrient;GO:0006778//porphyrin-containing compound metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0017144//drug metabolic process;GO:0052696//flavonoid glucuronidation;GO:0070980//biphenyl catabolic process;GO:0006789//bilirubin conjugation;GO:0007586//digestion;GO:0045939//negative regulation of steroid metabolic process;GO:0051552//flavone metabolic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:2001030//negative regulation of cellular glucuronidation;GO:0042573//retinoic acid metabolic process;GO:0052697//xenobiotic glucuronidation;GO:0042594//response to starvation;GO:0032496//response to lipopolysaccharide;GO:0006953//acute-phase response;GO:0008202//steroid metabolic process;GO:0046483//heterocycle metabolic process;GO:0071361//cellular response to ethanol;GO:0031100//organ regeneration;GO:0042493//response to drug;GO:0001889//liver development;GO:0006805//xenobiotic metabolic process;GO:0052695//cellular glucuronidation;GO:0044281//small molecule metabolic process,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0001972//retinoic acid binding;GO:0004857//enzyme inhibitor activity;GO:0015020//glucuronosyltransferase activity;GO:0019899//enzyme binding;GO:0005496//steroid binding,K00699//Metabolic pathways;Pentose and glucuronate interconversions;Drug metabolism - cytochrome P450;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism
54660,30,0,0,0,0,0,0,32,0,0,0,0,PCDHB18;protocadherin beta 18 pseudogene,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
54661,0,0,0,0,0,0,0,0,43,0,0,0,PCDHB17;protocadherin beta 17 pseudogene,-,-,-,-
54662,95,0,0,0,44,20,17,50,59,0,6,0,"TBC1D13;TBC1 domain family, member 13",-,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
54663,0,56,54,23,0,0,19,12,40,0,23,0,WDR74;WD repeat domain 74,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0016070//RNA metabolic process;GO:0001825//blastocyst formation,-,-
54664,0,0,0,17,11,0,26,0,38,0,0,0,TMEM106B;transmembrane protein 106B,GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006810//transport;GO:0008219//cell death;GO:0048813//dendrite morphogenesis;GO:0032418//lysosome localization,GO:0005515//protein binding,-
54665,0,0,0,8,0,0,8,0,59,0,0,0,RSBN1;round spermatid basic protein 1,GO:0005634//nucleus,-,-,-
5467,22,0,0,0,1,2,19,49,9,55,0,0,PPARD;peroxisome proliferator-activated receptor delta,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0043401//steroid hormone mediated signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0097190//apoptotic signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:0031589//cell-substrate adhesion;GO:0030522//intracellular receptor signaling pathway;GO:0006776//vitamin A metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008654//phospholipid biosynthetic process;GO:0033189//response to vitamin A;GO:0045600//positive regulation of fat cell differentiation;GO:0006635//fatty acid beta-oxidation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006091//generation of precursor metabolites and energy;GO:0008283//cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0014823//response to activity;GO:0010467//gene expression;GO:0007566//embryo implantation;GO:0042640//anagen;GO:0030308//negative regulation of cell growth;GO:0009749//response to glucose;GO:0009062//fatty acid catabolic process;GO:0008284//positive regulation of cell proliferation;GO:0006629//lipid metabolic process;GO:0007507//heart development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0046697//decidualization;GO:0015908//fatty acid transport;GO:0050728//negative regulation of inflammatory response;GO:0030154//cell differentiation;GO:0051546//keratinocyte migration;GO:0008366//axon ensheathment;GO:0050680//negative regulation of epithelial cell proliferation;GO:0045909//positive regulation of vasodilation;GO:0006006//glucose metabolic process;GO:0009299//mRNA transcription;GO:0042060//wound healing;GO:0043616//keratinocyte proliferation;GO:0015758//glucose transport;GO:0008203//cholesterol metabolic process;GO:0045684//positive regulation of epidermis development;GO:0014912//negative regulation of smooth muscle cell migration;GO:0060612//adipose tissue development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006029//proteoglycan metabolic process;GO:0032966//negative regulation of collagen biosynthetic process;GO:0071456//cellular response to hypoxia",GO:0070539//linoleic acid binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008144//drug binding;GO:0003713//transcription coactivator activity;GO:0008289//lipid binding;GO:0051059//NF-kappaB binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,K04504//Acute myeloid leukemia;Wnt signaling pathway;PPAR signaling pathway;Pathways in cancer
54674,0,0,0,0,0,0,0,24,0,0,0,0,LRRN3;leucine rich repeat neuronal 3,GO:0030131//clathrin adaptor complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001934//positive regulation of protein phosphorylation,GO:0032403//protein complex binding,K07523//Axon guidance
54675,0,19,16,19,70,0,0,3,32,89,0,1,CRLS1;cardiolipin synthase 1,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0032049//cardiolipin biosynthetic process;GO:0044281//small molecule metabolic process,-,K08744//Glycerophospholipid metabolism;Metabolic pathways
54676,80,50,0,5,13,19,0,0,31,0,0,0,GTPBP2;GTP binding protein 2,GO:0043231//intracellular membrane-bounded organelle,GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K14416//Legionellosis;mRNA surveillance pathway
54677,0,69,0,11,125,6,0,0,61,72,2,0,CROT;carnitine O-octanoyltransferase,GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,GO:0015936//coenzyme A metabolic process;GO:0015908//fatty acid transport;GO:0006631//fatty acid metabolic process;GO:0051791//medium-chain fatty acid metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0006091//generation of precursor metabolites and energy;GO:0044281//small molecule metabolic process;GO:0009437//carnitine metabolic process;GO:0044255//cellular lipid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase,GO:0008458//carnitine O-octanoyltransferase activity;GO:0005102//receptor binding,K05940//Peroxisome
5468,0,0,0,1,20,16,0,0,9,8,11,0,PPARG;peroxisome proliferator-activated receptor gamma,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0043401//steroid hormone mediated signaling pathway;GO:0030224//monocyte differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030855//epithelial cell differentiation;GO:0010871//negative regulation of receptor biosynthetic process;GO:0010887//negative regulation of cholesterol storage;GO:0033189//response to vitamin A;GO:0045600//positive regulation of fat cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0033993//response to lipid;GO:0032869//cellular response to insulin stimulus;GO:0009409//response to cold;GO:0001890//placenta development;GO:0051974//negative regulation of telomerase activity;GO:0010467//gene expression;GO:0055098//response to low-density lipoprotein particle;GO:0071285//cellular response to lithium ion;GO:0030308//negative regulation of cell growth;GO:0048469//cell maturation;GO:0006629//lipid metabolic process;GO:0045087//innate immune response;GO:0042593//glucose homeostasis;GO:0045713//low-density lipoprotein particle receptor biosynthetic process;GO:0007507//heart development;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0008217//regulation of blood pressure;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050873//brown fat cell differentiation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007584//response to nutrient;GO:0043627//response to estrogen;GO:0046321//positive regulation of fatty acid oxidation;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031000//response to caffeine;GO:0032526//response to retinoic acid;GO:0015909//long-chain fatty acid transport;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0050872//white fat cell differentiation;GO:0007165//signal transduction;GO:0060694//regulation of cholesterol transporter activity;GO:0010891//negative regulation of sequestering of triglyceride;GO:0002674//negative regulation of acute inflammatory response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045165//cell fate commitment;GO:0055088//lipid homeostasis;GO:0031100//organ regeneration;GO:0019395//fatty acid oxidation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042493//response to drug;GO:0042953//lipoprotein transport",GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003677//DNA binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0001012//RNA polymerase II regulatory region DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0050544//arachidonic acid binding;GO:0046965//retinoid X receptor binding;GO:0043565//sequence-specific DNA binding;GO:0033613//activating transcription factor binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004955//prostaglandin receptor activity;GO:0008144//drug binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0044212//transcription regulatory region DNA binding,K08530//Huntington's disease;PPAR signaling pathway;Pathways in cancer;Osteoclast differentiation;Thyroid cancer;Transcriptional misregulation in cancer
54680,0,0,0,4,19,13,0,0,21,0,0,0,"ZNHIT6;zinc finger, HIT-type containing 6",GO:0070062//extracellular vesicular exosome;GO:0070761//pre-snoRNP complex,GO:0000492//box C/D snoRNP assembly;GO:0042254//ribosome biogenesis,GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
54681,0,0,51,12,38,21,0,60,31,0,56,1,"P4HTM;prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,"GO:0031418//L-ascorbic acid binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0005509//calcium ion binding",-
54682,0,0,0,0,0,0,0,0,25,0,0,0,MANSC1;MANSC domain containing 1,GO:0016021//integral component of membrane,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism
5469,0,76,3,84,258,44,0,99,52,1,72,0,MED1;mediator complex subunit 1,GO:0016020//membrane;GO:0032993//protein-DNA complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005634//nucleus;GO:0016592//mediator complex,"GO:0002154//thyroid hormone mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0006590//thyroid hormone generation;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0030216//keratinocyte differentiation;GO:0048822//enucleate erythrocyte development;GO:0000902//cell morphogenesis;GO:0070371//ERK1 and ERK2 cascade;GO:2001141//regulation of RNA biosynthetic process;GO:0003406//retinal pigment epithelium development;GO:0031100//organ regeneration;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0070318//positive regulation of G0 to G1 transition;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0048821//erythrocyte development;GO:0044281//small molecule metabolic process;GO:2000273//positive regulation of receptor activity;GO:0045665//negative regulation of neuron differentiation;GO:0071383//cellular response to steroid hormone stimulus;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0060744//mammary gland branching involved in thelarche;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035855//megakaryocyte development;GO:0007595//lactation;GO:0060745//mammary gland branching involved in pregnancy;GO:0097067//cellular response to thyroid hormone stimulus;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0035050//embryonic heart tube development;GO:0006356//regulation of transcription from RNA polymerase I promoter;GO:0001892//embryonic placenta development;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0030224//monocyte differentiation;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0035162//embryonic hemopoiesis;GO:0010839//negative regulation of keratinocyte proliferation;GO:0045618//positive regulation of keratinocyte differentiation;GO:2000347//positive regulation of hepatocyte proliferation;GO:0035116//embryonic hindlimb morphogenesis;GO:0001525//angiogenesis;GO:0006702//androgen biosynthetic process;GO:0002088//lens development in camera-type eye;GO:0001889//liver development;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007420//brain development;GO:0051726//regulation of cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway",GO:0016922//ligand-dependent nuclear receptor binding;GO:0031490//chromatin DNA binding;GO:0030375//thyroid hormone receptor coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003713//transcription coactivator activity;GO:0042809//vitamin D receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042974//retinoic acid receptor binding;GO:0030331//estrogen receptor binding;GO:0004872//receptor activity;GO:0042975//peroxisome proliferator activated receptor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046966//thyroid hormone receptor binding;GO:0050693//LBD domain binding;GO:0003682//chromatin binding;GO:0001047//core promoter binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0036033//mediator complex binding;GO:0008134//transcription factor binding;GO:0003712//transcription cofactor activity,-
547,165,35,0,0,8,6,21,46,128,3,27,0,KIF1A;kinesin family member 1A,GO:0043005//neuron projection;GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0043025//neuronal cell body,GO:0008219//cell death;GO:0007018//microtubule-based movement;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0016192//vesicle-mediated transport;GO:0008152//metabolic process;GO:0008089//anterograde axon cargo transport;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0003774//motor activity;GO:0016887//ATPase activity;GO:0008017//microtubule binding,-
5470,0,0,0,7,0,0,0,0,27,0,0,0,"PPEF2;protein phosphatase, EF-hand calcium binding domain 2",GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005737//cytoplasm,GO:0007601//visual perception;GO:0050906//detection of stimulus involved in sensory perception;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0043409//negative regulation of MAPK cascade;GO:0043405//regulation of MAP kinase activity;GO:0006470//protein dephosphorylation;GO:0043506//regulation of JUN kinase activity,GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0030145//manganese ion binding;GO:0030544//Hsp70 protein binding;GO:0051879//Hsp90 protein binding;GO:0005506//iron ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding,-
54700,0,0,0,3,15,0,0,0,0,0,0,0,RRN3;RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0048872//homeostasis of number of cells;GO:0008283//cell proliferation;GO:0007028//cytoplasm organization;GO:1902254//negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator;GO:2000142//regulation of DNA-templated transcription, initiation;GO:0001701//in utero embryonic development;GO:0006360//transcription from RNA polymerase I promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007000//nucleolus organization;GO:0006361//transcription initiation from RNA polymerase I promoter",GO:0070063//RNA polymerase binding,-
54704,223,0,0,9,0,0,29,0,9,0,0,1,PDP1;pyruvate dehyrogenase phosphatase catalytic subunit 1,GO:0005759//mitochondrial matrix,GO:0035970//peptidyl-threonine dephosphorylation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity,-
54707,0,31,0,1,2,0,17,0,10,0,0,0,GPN2;GPN-loop GTPase 2,-,-,GO:0005525//GTP binding,-
54708,0,130,1,50,105,0,0,0,38,270,12,0,MARCH5;membrane-associated ring finger (C3HC4) 5,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane,GO:0070585//protein localization to mitochondrion;GO:0000209//protein polyubiquitination;GO:0051865//protein autoubiquitination;GO:0090140//regulation of mitochondrial fission;GO:0090141//positive regulation of mitochondrial fission;GO:0090344//negative regulation of cell aging,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0051020//GTPase binding,-
5471,0,0,0,0,24,1,20,0,7,0,0,0,PPAT;phosphoribosyl pyrophosphate amidotransferase,GO:0005829//cytosol,GO:0051289//protein homotetramerization;GO:0031100//organ regeneration;GO:0009116//nucleoside metabolic process;GO:0006164//purine nucleotide biosynthetic process;GO:0001822//kidney development;GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0035690//cellular response to drug;GO:0032869//cellular response to insulin stimulus;GO:0006189//'de novo' IMP biosynthetic process;GO:0009113//purine nucleobase biosynthetic process;GO:0007595//lactation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006543//glutamine catabolic process;GO:0060135//maternal process involved in female pregnancy;GO:0006144//purine nucleobase metabolic process,"GO:0004044//amidophosphoribosyltransferase activity;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding","K00764//Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fructose and mannose metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis"
54714,0,0,0,8,0,8,42,1,13,0,0,0,CNGB3;cyclic nucleotide gated channel beta 3,GO:1902495//transmembrane transporter complex;GO:0005887//integral component of plasma membrane;GO:0001750//photoreceptor outer segment,"GO:0006810//transport;GO:0007603//phototransduction, visible light;GO:0006812//cation transport;GO:0042391//regulation of membrane potential;GO:0007165//signal transduction;GO:0071805//potassium ion transmembrane transport;GO:0007601//visual perception",GO:0005222//intracellular cAMP activated cation channel activity;GO:0005223//intracellular cGMP activated cation channel activity;GO:0005249//voltage-gated potassium channel activity;GO:0030553//cGMP binding,-
54715,0,0,0,0,0,2,0,39,35,0,6,0,"RBFOX1;RNA binding protein, fox-1 homolog (C. elegans) 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network,GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0050885//neuromuscular process controlling balance;GO:0050658//RNA transport;GO:0043484//regulation of RNA splicing,GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008022//protein C-terminus binding;GO:0003723//RNA binding,-
54716,69,0,0,0,0,22,4,0,82,0,19,0,"SLC6A20;solute carrier family 6 (proline IMINO transporter), member 20",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane,GO:0006836//neurotransmitter transport;GO:0015816//glycine transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0003333//amino acid transmembrane transport;GO:0015824//proline transport;GO:0006865//amino acid transport,GO:0005328//neurotransmitter:sodium symporter activity;GO:0015171//amino acid transmembrane transporter activity,-
54718,0,0,0,0,0,28,30,0,32,0,0,0,"BTN2A3P;butyrophilin, subfamily 2, member A3, pseudogene",GO:0016021//integral component of membrane,-,-,-
54726,1,41,74,14,80,23,18,52,102,0,0,0,OTUD4;OTU deubiquitinase 4,-,GO:0006508//proteolysis;GO:0071108//protein K48-linked deubiquitination,GO:0044822//poly(A) RNA binding;GO:0004843//ubiquitin-specific protease activity,-
54729,0,0,0,0,0,0,0,63,0,0,15,0,NKX1-1;NK1 homeobox 1,GO:0005634//nucleus,"GO:0050877//neurological system process;GO:0006629//lipid metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0010906//regulation of glucose metabolic process",GO:0043565//sequence-specific DNA binding,-
5473,0,0,0,0,0,0,14,0,0,0,0,0,PPBP;pro-platelet basic protein (chemokine (C-X-C motif) ligand 7),GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0007596//blood coagulation;GO:0015758//glucose transport;GO:0006955//immune response;GO:0002576//platelet degranulation;GO:0042742//defense response to bacterium;GO:0051781//positive regulation of cell division;GO:0060326//cell chemotaxis;GO:0002523//leukocyte migration involved in inflammatory response;GO:0030168//platelet activation,GO:0005355//glucose transmembrane transporter activity;GO:0008083//growth factor activity;GO:0008009//chemokine activity,K10029//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
54732,0,3,0,0,0,0,0,0,10,0,0,0,TMED9;transmembrane emp24 protein transport domain containing 9,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007030//Golgi organization;GO:0032527//protein exit from endoplasmic reticulum;GO:0010638//positive regulation of organelle organization;GO:0048205//COPI coating of Golgi vesicle;GO:0034498//early endosome to Golgi transport,GO:0019905//syntaxin binding;GO:0005515//protein binding,-
54733,24,0,0,2,35,0,10,0,45,0,0,0,"SLC35F2;solute carrier family 35, member F2",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
54734,0,0,0,0,0,0,0,0,35,0,0,0,"RAB39A;RAB39A, member RAS oncogene family",GO:0045335//phagocytic vesicle;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane,GO:0090385//phagosome-lysosome fusion;GO:0015031//protein transport;GO:0090383//phagosome acidification;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
54737,11,0,0,13,48,25,0,0,28,0,0,0,MPHOSPH8;M-phase phosphoprotein 8,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005720//nuclear heterochromatin;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0000788//nuclear nucleosome,"GO:0044030//regulation of DNA methylation;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0035064//methylated histone binding,K11447//Transcriptional misregulation in cancer;K12460//Neurotrophin signaling pathway;K08803//Bladder cancer;Pathways in cancer
54738,0,0,0,0,0,0,29,0,31,0,1,0,FEV;FEV (ETS oncogene family),GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0048665//neuron fate specification;GO:0030154//cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042551//neuron maturation",GO:0003690//double-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09437//Transcriptional misregulation in cancer
54739,0,0,0,0,0,0,24,0,19,0,0,0,XAF1;XIAP associated factor 1,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0060337//type I interferon signaling pathway;GO:0006915//apoptotic process;GO:0031333//negative regulation of protein complex assembly;GO:0035456//response to interferon-beta;GO:0019221//cytokine-mediated signaling pathway,GO:0008270//zinc ion binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
54741,0,0,0,7,28,39,0,0,25,0,0,0,LEPROT;leptin receptor overlapping transcript,GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0010008//endosome membrane,GO:2000009//negative regulation of protein localization to cell surface;GO:0060400//negative regulation of growth hormone receptor signaling pathway;GO:0046426//negative regulation of JAK-STAT cascade,GO:0005102//receptor binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
54742,4,0,0,0,78,9,0,0,0,58,7,0,"LY6K;lymphocyte antigen 6 complex, locus K",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031225//anchored component of membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005576//extracellular region,-,-,-
54749,0,24,0,11,16,0,0,0,17,0,0,0,EPDR1;ependymin related 1,GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,GO:0007160//cell-matrix adhesion,GO:0005509//calcium ion binding,-
5475,0,0,1,0,0,12,1,0,52,0,7,0,"PPEF1;protein phosphatase, EF-hand calcium binding domain 1",GO:0005829//cytosol,"GO:0050906//detection of stimulus involved in sensory perception;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0006470//protein dephosphorylation;GO:0007603//phototransduction, visible light",GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0005509//calcium ion binding;GO:0030145//manganese ion binding,-
54751,0,0,0,8,0,0,0,8,7,0,0,0,FBLIM1;filamin binding LIM protein 1,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0001725//stress fiber;GO:0005938//cell cortex,GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0008360//regulation of cell shape;GO:0033623//regulation of integrin activation,GO:0031005//filamin binding;GO:0008270//zinc ion binding,K06273//Focal adhesion
54752,0,0,0,31,20,0,0,0,22,0,58,0,FNDC8;fibronectin type III domain containing 8,GO:0005634//nucleus,-,-,-
54753,0,0,0,2,0,16,0,1,17,0,6,294,ZNF853;zinc finger protein 853,-,-,GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
54754,2,0,0,0,0,0,0,0,0,0,0,0,NUTM2F;NUT family member 2F,-,-,-,K06236//Focal adhesion;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction
54756,77,1,0,0,0,17,20,0,17,0,1,0,IL17RD;interleukin 17 receptor D,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0007165//signal transduction,-,-
54757,77,0,0,8,1,0,60,0,17,0,3,372,"FAM20A;family with sequence similarity 20, member A",GO:0005623//cell;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0070166//enamel mineralization;GO:0044691//tooth eruption;GO:0055074//calcium ion homeostasis,-,-
54758,0,0,48,19,13,0,0,0,0,0,9,0,KLHDC4;kelch domain containing 4,-,-,GO:0005515//protein binding,-
5476,0,5,9,0,64,24,0,127,36,0,15,2,CTSA;cathepsin A,GO:0043202//lysosomal lumen;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0006886//intracellular protein transport;GO:0006687//glycosphingolipid metabolic process;GO:0006508//proteolysis;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0043085//positive regulation of catalytic activity,GO:0004185//serine-type carboxypeptidase activity;GO:0008047//enzyme activator activity;GO:0004180//carboxypeptidase activity,K13289//Lysosome;Renin-angiotensin system
54760,0,18,0,0,8,0,20,0,33,0,37,0,PCSK4;proprotein convertase subtilisin/kexin type 4,GO:0016021//integral component of membrane;GO:0002080//acrosomal membrane,GO:0006508//proteolysis;GO:0007340//acrosome reaction;GO:0048240//sperm capacitation;GO:0007339//binding of sperm to zona pellucida,GO:0004252//serine-type endopeptidase activity,-
54762,0,0,0,6,16,42,80,0,106,0,2,0,GRAMD1C;GRAM domain containing 1C,GO:0016021//integral component of membrane,-,-,-
54763,0,0,0,0,0,0,0,52,0,0,0,0,ROPN1;rhophilin associated tail protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
54764,0,35,36,45,130,0,72,1,51,0,46,0,"ZRANB1;zinc finger, RAN-binding domain containing 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0035523//protein K29-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination;GO:0016477//cell migration;GO:0022604//regulation of cell morphogenesis;GO:0016055//Wnt signaling pathway;GO:0071947//protein deubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0070536//protein K63-linked deubiquitination;GO:0007010//cytoskeleton organization;GO:0030177//positive regulation of Wnt signaling pathway,GO:0005515//protein binding;GO:0070530//K63-linked polyubiquitin binding;GO:0004843//ubiquitin-specific protease activity;GO:0008270//zinc ion binding;GO:0004221//ubiquitin thiolesterase activity,-
54765,0,17,1,41,101,0,0,0,13,0,0,373,TRIM44;tripartite motif containing 44,GO:0005622//intracellular,-,GO:0005515//protein binding;GO:0008270//zinc ion binding,-
54766,0,0,0,0,7,0,13,3,2,0,0,0,BTG4;B-cell translocation gene 4,-,GO:0008285//negative regulation of cell proliferation;GO:0007050//cell cycle arrest;GO:0030182//neuron differentiation;GO:0045930//negative regulation of mitotic cell cycle,-,K14443//RNA degradation
54768,17,2,0,4,39,74,130,53,249,0,21,0,"HYDIN;HYDIN, axonemal central pair apparatus protein",GO:0005929//cilium,GO:0042384//cilium assembly;GO:0021591//ventricular system development;GO:0003341//cilium movement;GO:0060438//trachea development;GO:0002064//epithelial cell development,-,-
54769,0,0,0,0,0,23,20,0,9,0,0,0,"DIRAS2;DIRAS family, GTP-binding RAS-like 2",GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0043406//positive regulation of MAP kinase activity,GO:0005525//GTP binding,-
54776,10,0,0,0,0,0,0,58,50,0,5,15,"PPP1R12C;protein phosphatase 1, regulatory subunit 12C",GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12329//Vascular smooth muscle contraction;K06270//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Long-term potentiation;Focal adhesion
54777,0,0,0,0,0,75,121,94,86,250,14,0,TTC40;tetratricopeptide repeat domain 40,-,-,-,-
54778,0,0,0,2,13,25,0,0,10,0,0,0,RNF111;ring finger protein 111,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005730//nucleolus,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0007389//pattern specification process;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0010467//gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0031398//positive regulation of protein ubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway",GO:0008270//zinc ion binding;GO:0032184//SUMO polymer binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0046332//SMAD binding,-
54780,0,0,0,15,14,0,0,0,19,0,4,0,NSMCE4A;non-SMC element 4 homolog A (S. cerevisiae),"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030915//Smc5-Smc6 complex",GO:0006310//DNA recombination;GO:0006281//DNA repair;GO:2001022//positive regulation of response to DNA damage stimulus,GO:0005515//protein binding,-
54784,0,10,0,0,4,0,0,1,16,0,0,0,"ALKBH4;alkB, alkylation repair homolog 4 (E. coli)",GO:0030496//midbody;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070938//contractile ring,"GO:0055114//oxidation-reduction process;GO:0006351//transcription, DNA-templated;GO:0006482//protein demethylation;GO:0036090//cleavage furrow ingression;GO:0031032//actomyosin structure organization;GO:0006355//regulation of transcription, DNA-templated","GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0046872//metal ion binding;GO:0032451//demethylase activity;GO:0003779//actin binding",-
54785,0,34,51,13,18,0,0,0,17,0,74,0,C17orf59;chromosome 17 open reading frame 59,-,-,-,-
54788,70,0,1,4,14,0,36,4,60,0,0,0,"DNAJB12;DnaJ (Hsp40) homolog, subfamily B, member 12",GO:0016020//membrane;GO:0016021//integral component of membrane,-,-,K09518//Protein processing in endoplasmic reticulum
5479,0,118,0,34,54,0,0,0,8,0,57,0,PPIB;peptidylprolyl isomerase B (cyclophilin B),GO:0005925//focal adhesion;GO:0032991//macromolecular complex;GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0030198//extracellular matrix organization;GO:0040018//positive regulation of multicellular organism growth;GO:0000413//protein peptidyl-prolyl isomerization;GO:0050821//protein stabilization;GO:0060348//bone development;GO:0061077//chaperone-mediated protein folding;GO:1901873//regulation of post-translational protein modification,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0051082//unfolded protein binding;GO:0042277//peptide binding;GO:0005518//collagen binding;GO:0032403//protein complex binding,-
54790,0,59,1,24,151,63,39,0,174,91,7,0,TET2;tet methylcytosine dioxygenase 2,-,GO:0007049//cell cycle;GO:0030099//myeloid cell differentiation;GO:0080111//DNA demethylation;GO:0001822//kidney development;GO:0009791//post-embryonic development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006211//5-methylcytosine catabolic process;GO:0006493//protein O-linked glycosylation;GO:0080182//histone H3-K4 trimethylation;GO:0055114//oxidation-reduction process,GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0008198//ferrous iron binding;GO:0005515//protein binding;GO:0070579//methylcytosine dioxygenase activity,-
54793,0,0,1,27,36,0,18,0,23,166,7,0,KCTD9;potassium channel tetramerization domain containing 9,-,GO:0051260//protein homooligomerization,-,-
54795,0,0,0,6,2,7,7,0,81,49,8,0,"TRPM4;transient receptor potential cation channel, subfamily M, member 4",GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0034220//ion transmembrane transport;GO:0016925//protein sumoylation;GO:0042310//vasoconstriction;GO:0042391//regulation of membrane potential;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0061337//cardiac conduction;GO:0002407//dendritic cell chemotaxis;GO:0002724//regulation of T cell cytokine production;GO:0008284//positive regulation of cell proliferation,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0005227//calcium activated cation channel activity;GO:0005262//calcium channel activity,-
54796,36,0,0,4,1,16,12,87,23,51,0,425,BNC2;basonuclin 2,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0003416//endochondral bone growth;GO:0043586//tongue development;GO:0060021//palate development;GO:0060485//mesenchyme development;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
54797,75,0,0,0,0,0,1,0,0,0,0,0,MED18;mediator complex subunit 18,GO:0016592//mediator complex,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity,-
54798,0,0,0,0,0,99,0,12,209,342,21,0,DCHS2;dachsous cadherin-related 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
54799,0,0,1,32,58,38,11,0,36,0,0,0,MBTD1;mbt domain containing 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0048706//embryonic skeletal system development;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification",GO:0008270//zinc ion binding,-
5480,0,0,0,4,1,8,7,0,18,0,13,0,PPIC;peptidylprolyl isomerase C (cyclophilin C),GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization;GO:0007165//signal transduction,GO:0016018//cyclosporin A binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0051082//unfolded protein binding,-
54800,0,70,1,69,43,10,34,0,61,0,14,0,KLHL24;kelch-like family member 24,GO:0030424//axon;GO:0043204//perikaryon;GO:0005737//cytoplasm,-,-,-
54801,0,32,0,1,20,0,0,0,48,0,9,0,"HAUS6;HAUS augmin-like complex, subunit 6",GO:0005874//microtubule;GO:0005819//spindle;GO:0070652//HAUS complex;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0051225//spindle assembly;GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization,-,-
54802,0,1,0,6,13,8,0,0,0,0,0,0,TRIT1;tRNA isopentenyltransferase 1,GO:0005739//mitochondrion,GO:0008033//tRNA processing,GO:0005524//ATP binding;GO:0052381//tRNA dimethylallyltransferase activity;GO:0046872//metal ion binding,K00791//Biosynthesis of secondary metabolites;Zeatin biosynthesis;Metabolic pathways
54805,74,0,0,0,0,1,0,4,0,0,0,1,CNNM2;cyclin M2,GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport;GO:0010960//magnesium ion homeostasis,GO:0030554//adenyl nucleotide binding,-
54806,0,65,1,1,54,14,87,0,44,0,2,0,AHI1;Abelson helper integration site 1,GO:0031513//nonmotile primary cilium;GO:0001750//photoreceptor outer segment;GO:0005911//cell-cell junction;GO:0036038//TCTN-B9D complex;GO:0005813//centrosome;GO:0036064//ciliary basal body;GO:0005912//adherens junction;GO:0005814//centriole;GO:0005929//cilium;GO:0072372//primary cilium,GO:0043066//negative regulation of apoptotic process;GO:0039008//pronephric nephron tubule morphogenesis;GO:0007417//central nervous system development;GO:0001947//heart looping;GO:0060271//cilium morphogenesis;GO:0030862//positive regulation of polarized epithelial cell differentiation;GO:0016192//vesicle-mediated transport;GO:0006903//vesicle targeting;GO:0039023//pronephric duct morphogenesis;GO:0065001//specification of axis polarity;GO:0042384//cilium assembly;GO:0033365//protein localization to organelle;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0070986//left/right axis specification;GO:0002092//positive regulation of receptor internalization;GO:0071599//otic vesicle development;GO:0034613//cellular protein localization;GO:0035844//cloaca development;GO:0010842//retina layer formation;GO:0001738//morphogenesis of a polarized epithelium;GO:0050795//regulation of behavior;GO:0035845//photoreceptor cell outer segment organization;GO:0070121//Kupffer's vesicle development;GO:0030902//hindbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding,-
54807,0,0,0,10,38,0,0,0,12,0,0,0,ZNF586;zinc finger protein 586,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
54808,0,1,0,5,61,9,25,15,39,0,0,322,DYM;dymeclin,GO:0005737//cytoplasm;GO:0005794//Golgi apparatus,GO:0007030//Golgi organization;GO:0060348//bone development,GO:0019899//enzyme binding;GO:0005515//protein binding,-
54809,0,0,0,0,16,31,0,0,0,0,0,0,SAMD9;sterile alpha motif domain containing 9,GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle,-,GO:0005515//protein binding,-
5481,0,0,41,59,65,8,0,0,0,0,13,0,PPID;peptidylprolyl isomerase D,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006457//protein folding;GO:0006915//apoptotic process;GO:0034389//lipid particle organization;GO:0015031//protein transport;GO:0061077//chaperone-mediated protein folding;GO:0043065//positive regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050714//positive regulation of protein secretion;GO:0045070//positive regulation of viral genome replication;GO:0006461//protein complex assembly;GO:0000413//protein peptidyl-prolyl isomerization;GO:0071492//cellular response to UV-A;GO:0019076//viral release from host cell,GO:0016018//cyclosporin A binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding;GO:0030544//Hsp70 protein binding;GO:0051879//Hsp90 protein binding;GO:0030331//estrogen receptor binding,-
54810,0,0,0,0,0,0,44,0,4,0,0,0,"GIPC2;GIPC PDZ domain containing family, member 2",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,-,-
54811,0,0,0,0,34,0,0,0,0,0,0,0,ZNF562;zinc finger protein 562,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
54812,0,185,20,151,540,0,0,0,8,0,35,0,AFTPH;aftiphilin,GO:0030121//AP-1 adaptor complex;GO:0005829//cytosol,GO:0015031//protein transport,GO:0030276//clathrin binding,-
54813,0,21,0,9,17,3,15,0,13,11,0,1,KLHL28;kelch-like family member 28,-,-,-,-
54814,0,0,0,0,0,0,0,0,35,0,0,0,QPCTL;glutaminyl-peptide cyclotransferase-like,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,"GO:0017186//peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase",GO:0016603//glutaminyl-peptide cyclotransferase activity;GO:0008270//zinc ion binding,-
54816,12,0,0,25,38,57,0,0,41,0,11,0,ZNF280D;zinc finger protein 280D,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
54820,0,0,0,0,1,24,0,0,11,0,21,327,NDE1;nudE neurodevelopment protein 1,GO:0005829//cytosol;GO:0005874//microtubule;GO:0000776//kinetochore;GO:0016020//membrane;GO:0032154//cleavage furrow;GO:0000777//condensed chromosome kinetochore;GO:0031616//spindle pole centrosome;GO:0005813//centrosome,GO:0007067//mitotic nuclear division;GO:0007405//neuroblast proliferation;GO:0051298//centrosome duplication;GO:0051303//establishment of chromosome localization;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0047496//vesicle transport along microtubule;GO:0001764//neuron migration;GO:0007020//microtubule nucleation;GO:0000132//establishment of mitotic spindle orientation;GO:0021987//cerebral cortex development,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0019904//protein domain specific binding,K06560//Tuberculosis;Phagosome;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
54821,77,0,0,7,0,3,33,0,30,0,0,0,ERCC6L;excision repair cross-complementation group 6-like,GO:0016020//membrane;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol,GO:0008152//metabolic process;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle,GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding,K10841//Nucleotide excision repair
54823,58,0,17,0,12,0,0,0,49,0,12,0,SWT1;SWT1 RNA endoribonuclease homolog (S. cerevisiae),-,-,-,K11124//mRNA surveillance pathway
54825,0,35,53,0,5,41,0,52,46,80,4,611,CDHR2;cadherin-related family member 2,GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction,GO:0007155//cell adhesion;GO:0030308//negative regulation of cell growth;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
54826,0,0,0,9,1,16,0,0,18,0,0,0,GIN1;gypsy retrotransposon integrase 1,-,GO:0015074//DNA integration,GO:0003676//nucleic acid binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption
54827,0,0,0,0,0,0,0,0,24,4,0,0,"NXPE4;neurexophilin and PC-esterase domain family, member 4",GO:0070062//extracellular vesicular exosome,-,-,-
54828,0,0,1,0,11,11,0,0,20,0,7,0,BCAS3;breast carcinoma amplified sequence 3,GO:0045111//intermediate filament cytoskeleton;GO:0031252//cell leading edge;GO:0005881//cytoplasmic microtubule;GO:0035327//transcriptionally active chromatin;GO:0005737//cytoplasm;GO:0071944//cell periphery;GO:0005634//nucleus,GO:0032864//activation of Cdc42 GTPase activity;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0035148//tube formation;GO:0010595//positive regulation of endothelial cell migration;GO:0043085//positive regulation of catalytic activity;GO:0090316//positive regulation of intracellular protein transport;GO:0034259//negative regulation of Rho GTPase activity;GO:0043089//positive regulation of Cdc42 GTPase activity;GO:2000114//regulation of establishment of cell polarity;GO:0007030//Golgi organization;GO:0051491//positive regulation of filopodium assembly;GO:0031023//microtubule organizing center organization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051895//negative regulation of focal adhesion assembly;GO:0071391//cellular response to estrogen stimulus,GO:0035035//histone acetyltransferase binding;GO:0035257//nuclear hormone receptor binding;GO:0003682//chromatin binding;GO:0010698//acetyltransferase activator activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0008134//transcription factor binding,-
54829,0,0,0,0,0,0,0,0,7,0,0,0,ASPN;asporin,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0030282//bone mineralization;GO:0070171//negative regulation of tooth mineralization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0005518//collagen binding;GO:0005509//calcium ion binding,-
54830,0,0,0,0,0,0,38,0,12,0,0,0,NUP62CL;nucleoporin 62kDa C-terminal like,GO:0005643//nuclear pore,GO:0015031//protein transport,GO:0017056//structural constituent of nuclear pore,K14306//RNA transport
54831,0,0,0,0,0,14,0,10,17,0,1,0,BEST2;bestrophin 2,GO:0005886//plasma membrane;GO:0005929//cilium;GO:0034707//chloride channel complex,GO:0007608//sensory perception of smell;GO:1902476//chloride transmembrane transport;GO:0051899//membrane depolarization,GO:0005254//chloride channel activity,K13879//Salivary secretion
54832,172,108,0,82,195,18,92,3,233,0,1,0,VPS13C;vacuolar protein sorting 13 homolog C (S. cerevisiae),GO:0070062//extracellular vesicular exosome,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
54834,0,101,1,56,58,18,71,75,35,0,0,0,GDAP2;ganglioside induced differentiation associated protein 2,GO:0005765//lysosomal membrane,GO:0032526//response to retinoic acid,-,K11447//Transcriptional misregulation in cancer
54836,0,19,0,4,8,18,0,0,29,0,0,236,BSPRY;B-box and SPRY domain containing,GO:0031252//cell leading edge;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm,GO:0006816//calcium ion transport,GO:0008270//zinc ion binding,-
54838,0,5,0,6,24,0,5,15,44,78,12,0,WBP1L;WW domain binding protein 1-like,GO:0016021//integral component of membrane,-,-,-
54839,234,0,0,20,1,0,35,157,83,0,7,268,LRRC49;leucine rich repeat containing 49,GO:0005737//cytoplasm;GO:0005874//microtubule,-,-,-
54840,0,0,0,19,10,0,0,0,13,0,9,0,APTX;aprataxin,GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0098506//polynucleotide 3' dephosphorylation;GO:0006302//double-strand break repair;GO:0006974//cellular response to DNA damage stimulus;GO:0008219//cell death;GO:0031647//regulation of protein stability;GO:0000012//single strand break repair;GO:0042542//response to hydrogen peroxide;GO:0006266//DNA ligation;GO:0000738//DNA catabolic process, exonucleolytic;GO:0016311//dephosphorylation",GO:0033699//DNA 5'-adenosine monophosphate hydrolase activity;GO:0003690//double-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0051219//phosphoprotein binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046403//polynucleotide 3'-phosphatase activity;GO:0003682//chromatin binding;GO:0047485//protein N-terminus binding;GO:0008967//phosphoglycolate phosphatase activity;GO:0003725//double-stranded RNA binding,-
54841,0,0,0,0,31,0,0,0,0,0,1,0,"BIVM;basic, immunoglobulin-like variable motif containing",GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,K10846//Nucleotide excision repair
54842,0,0,0,10,13,0,0,1,8,0,0,0,MFSD6;major facilitator superfamily domain containing 6,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0055085//transmembrane transport,-,-
54843,0,1,0,32,39,0,0,68,29,96,0,0,SYTL2;synaptotagmin-like 2,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0042470//melanosome;GO:0005737//cytoplasm;GO:0019897//extrinsic component of plasma membrane;GO:0005634//nucleus;GO:0070382//exocytic vesicle,GO:0006886//intracellular protein transport;GO:0010923//negative regulation of phosphatase activity;GO:0006887//exocytosis;GO:0016192//vesicle-mediated transport;GO:0070257//positive regulation of mucus secretion;GO:0006904//vesicle docking involved in exocytosis,"GO:0042043//neurexin family protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0017137//Rab GTPase binding;GO:0001786//phosphatidylserine binding;GO:0019902//phosphatase binding;GO:0005515//protein binding",K15290//Synaptic vesicle cycle
54845,0,35,2,31,66,0,40,0,33,0,0,0,ESRP1;epithelial splicing regulatory protein 1,GO:0005634//nucleus,GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing,GO:0003729//mRNA binding;GO:0000166//nucleotide binding,-
54847,0,0,0,0,0,1,9,1,22,0,28,0,"SIDT1;SID1 transmembrane family, member 1",GO:0016021//integral component of membrane,GO:0033227//dsRNA transport,GO:0051033//RNA transmembrane transporter activity,K03914//Endocytosis;Regulation of actin cytoskeleton;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;Calcium signaling pathway
54848,0,0,0,10,5,22,0,0,0,0,0,0,ARHGEF38;Rho guanine nucleotide exchange factor (GEF) 38,GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K03099//B cell receptor signaling pathway;Jak-STAT signaling pathway;Acute myeloid leukemia;Fc epsilon RI signaling pathway;Glioma;Dorso-ventral axis formation;Focal adhesion;MAPK signaling pathway - fly;Endometrial cancer;Non-small cell lung cancer;Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;Alcoholism;Prostate cancer;GnRH signaling pathway;Pathways in cancer;Chemokine signaling pathway;Gap junction;Insulin signaling pathway;ErbB signaling pathway;Renal cell carcinoma;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Chronic myeloid leukemia
54849,1,0,0,77,8,8,22,26,45,0,89,0,DEF8;differentially expressed in FDCP 8 homolog (mouse),-,GO:0035556//intracellular signal transduction,GO:0008270//zinc ion binding,-
54850,0,1,0,0,0,0,0,0,0,0,0,0,FBXL12;F-box and leucine-rich repeat protein 12,GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0005515//protein binding,-
54851,0,0,0,0,14,0,0,0,0,0,0,0,ANKRD49;ankyrin repeat domain 49,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated",-,-
54852,0,0,0,0,4,14,15,0,7,0,6,0,PAQR5;progestin and adipoQ receptor family member V,GO:0016021//integral component of membrane,GO:0048477//oogenesis;GO:0007275//multicellular organismal development,GO:0004872//receptor activity;GO:0005496//steroid binding,K07297//Adipocytokine signaling pathway
54853,0,0,1,0,29,0,17,0,0,0,0,0,WDR55;WD repeat domain 55,GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0006364//rRNA processing,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
54854,0,0,0,0,0,0,0,0,0,0,3,0,"FAM83E;family with sequence similarity 83, member E",-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
54855,0,29,0,20,127,22,18,1,45,0,6,3,"FAM46C;family with sequence similarity 46, member C",-,-,-,-
54856,1,33,3,24,136,42,0,1,86,59,31,0,GON4L;gon-4-like (C. elegans),GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
54857,0,0,0,0,0,0,64,0,24,0,0,0,GDPD2;glycerophosphodiester phosphodiesterase domain containing 2,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process,GO:0047394//glycerophosphoinositol inositolphosphodiesterase activity;GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0046872//metal ion binding,-
54859,102,0,1,0,33,18,0,0,1,54,2,0,ELP6;elongator acetyltransferase complex subunit 6,GO:0033588//Elongator holoenzyme complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization;GO:0030335//positive regulation of cell migration",-,-
548596,0,0,0,0,0,0,0,2,0,0,0,0,"CKMT1A;creatine kinase, mitochondrial 1A",GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006600//creatine metabolic process;GO:0016310//phosphorylation,GO:0004111//creatine kinase activity;GO:0005524//ATP binding,K00933//Arginine and proline metabolism;Metabolic pathways
54860,0,0,0,0,0,0,0,0,16,0,0,0,"MS4A12;membrane-spanning 4-domains, subfamily A, member 12",GO:0016021//integral component of membrane,-,-,K08090//Asthma;Fc epsilon RI signaling pathway;K06466//Hematopoietic cell lineage
54861,0,0,0,32,61,0,20,0,44,0,0,0,SNRK;SNF related kinase,GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0030099//myeloid cell differentiation,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
54862,29,0,0,1,0,37,44,0,4,13,6,0,CC2D1A;coiled-coil and C2 domain containing 1A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007165//signal transduction",GO:0004871//signal transducer activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K13911//Salivary secretion
54863,0,0,0,0,0,0,0,2,28,0,0,0,"TOR4A;torsin family 4, member A",GO:0016021//integral component of membrane,GO:0051085//chaperone mediated protein folding requiring cofactor,GO:0005524//ATP binding,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
548645,0,1,0,8,0,0,0,0,0,0,0,0,"DNAJC25;DnaJ (Hsp40) homolog, subfamily C , member 25",GO:0016021//integral component of membrane,-,-,K09523//Protein processing in endoplasmic reticulum;Influenza A
54865,0,0,0,13,29,20,0,55,9,0,0,0,GPATCH4;G patch domain containing 4,-,-,GO:0044822//poly(A) RNA binding,K15188//Transcriptional misregulation in cancer
54866,155,0,0,0,0,0,0,0,7,0,0,0,"PPP1R14D;protein phosphatase 1, regulatory (inhibitor) subunit 14D",GO:0005737//cytoplasm,GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity,GO:0004864//protein phosphatase inhibitor activity,K12328//Vascular smooth muscle contraction
54867,0,0,0,1,0,0,33,59,45,85,0,0,TMEM214;transmembrane protein 214,GO:0005789//endoplasmic reticulum membrane;GO:0005881//cytoplasmic microtubule;GO:0016021//integral component of membrane,GO:0006915//apoptotic process,-,-
54868,0,0,0,0,0,37,1,0,10,5,0,0,TMEM104;transmembrane protein 104,GO:0016021//integral component of membrane,-,-,-
54869,81,0,0,0,0,0,1,0,9,0,8,0,EPS8L1;EPS8-like 1,GO:0032587//ruffle membrane;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0005737//cytoplasm,GO:1900029//positive regulation of ruffle assembly;GO:0032855//positive regulation of Rac GTPase activity;GO:0032321//positive regulation of Rho GTPase activity;GO:0035023//regulation of Rho protein signal transduction;GO:0007266//Rho protein signal transduction,GO:0003779//actin binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0042608//T cell receptor binding,K07365//T cell receptor signaling pathway;Axon guidance;Pathogenic Escherichia coli infection;ErbB signaling pathway
54870,0,0,0,14,33,16,1,0,21,103,1,0,QRICH1;glutamine-rich 1,GO:0005634//nucleus;GO:0005730//nucleolus,-,-,-
54872,84,0,0,0,8,13,36,0,26,0,0,0,"PIGG;phosphatidylinositol glycan anchor biosynthesis, class G",GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification,GO:0051267//CP2 mannose-ethanolamine phosphotransferase activity,K05310//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
54873,0,0,0,0,15,0,0,0,10,0,0,0,PALMD;palmdelphin,GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0016020//membrane,GO:0008360//regulation of cell shape,-,-
54874,0,89,0,41,218,0,9,0,50,77,0,0,FNBP1L;formin binding protein 1-like,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0051491//positive regulation of filopodium assembly;GO:0006900//membrane budding;GO:0006914//autophagy;GO:0010324//membrane invagination;GO:0030050//vesicle transport along actin filament;GO:0072583//clathrin-mediated endocytosis;GO:0016050//vesicle organization;GO:0097320//membrane tubulation,GO:0008289//lipid binding;GO:0005515//protein binding,K07196//Insulin signaling pathway
54875,0,0,0,2,11,20,45,0,130,0,0,0,"CNTLN;centlein, centrosomal protein",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005814//centriole;GO:0070062//extracellular vesicular exosome,GO:0023014//signal transduction by phosphorylation;GO:0000160//phosphorelay signal transduction system;GO:0010457//centriole-centriole cohesion;GO:0033365//protein localization to organelle,"GO:0019904//protein domain specific binding;GO:0000155//phosphorelay sensor kinase activity;GO:0030674//protein binding, bridging;GO:0019901//protein kinase binding",K11447//Transcriptional misregulation in cancer;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
54876,0,0,0,56,69,13,0,0,1,60,0,0,DCAF16;DDB1 and CUL4 associated factor 16,GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:0016567//protein ubiquitination,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
54877,47,0,0,0,113,58,0,27,92,0,0,1,"ZCCHC2;zinc finger, CCHC domain containing 2",GO:0005737//cytoplasm,-,GO:0035091//phosphatidylinositol binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,K12185//Endocytosis
54878,93,42,0,15,103,0,63,0,34,0,0,45,DPP8;dipeptidyl-peptidase 8,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,GO:0006508//proteolysis;GO:0006955//immune response,GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity,-
54879,0,0,0,0,0,21,28,0,20,0,0,0,ST7L;suppression of tumorigenicity 7 like,GO:0016021//integral component of membrane,GO:0030308//negative regulation of cell growth,-,-
54880,0,29,0,31,23,24,10,0,11,0,0,0,BCOR;BCL6 corepressor,GO:0031519//PcG protein complex;GO:0005634//nucleus,"GO:0042476//odontogenesis;GO:0030502//negative regulation of bone mineralization;GO:0007507//heart development;GO:0035518//histone H2A monoubiquitination;GO:0070171//negative regulation of tooth mineralization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000415//negative regulation of histone H3-K36 methylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0065001//specification of axis polarity;GO:0060021//palate development",GO:0042826//histone deacetylase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0008134//transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0003714//transcription corepressor activity,-
54881,81,43,0,40,39,0,19,0,0,7,13,0,TEX10;testis expressed 10,GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0071339//MLL1 complex,-,GO:0005515//protein binding,-
54882,20,0,0,0,6,0,0,0,7,0,0,0,ANKHD1;ankyrin repeat and KH domain containing 1,GO:0005737//cytoplasm,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
54883,0,24,0,3,18,0,21,0,39,0,0,0,CWC25;CWC25 spliceosome-associated protein homolog (S. cerevisiae),-,-,-,K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
54884,0,1,0,17,1,22,15,0,6,0,0,0,"RETSAT;retinol saturase (all-trans-retinol 13,14-reductase)",GO:0016020//membrane;GO:0005640//nuclear outer membrane;GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane,GO:0042572//retinol metabolic process;GO:0055114//oxidation-reduction process,"GO:0016491//oxidoreductase activity;GO:0051786//all-trans-retinol 13,14-reductase activity",K09516//Retinol metabolism
54885,0,27,1,17,58,0,23,0,45,0,8,0,"TBC1D8B;TBC1 domain family, member 8B (with GRAM domain)",-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity;GO:0005509//calcium ion binding,-
54886,118,0,0,0,0,0,0,52,6,144,0,0,LPPR1;lipid phosphate phosphatase-related protein type 1,GO:0016021//integral component of membrane,GO:0007399//nervous system development;GO:0008152//metabolic process,GO:0003824//catalytic activity,K01080//Sphingolipid metabolism;Ether lipid metabolism;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism
54887,126,74,0,16,114,15,43,1,64,151,11,0,UHRF1BP1;UHRF1 binding protein 1,-,-,GO:0042826//histone deacetylase binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
54888,0,1,1,31,145,0,17,27,30,0,3,0,"NSUN2;NOP2/Sun RNA methyltransferase family, member 2",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005730//nucleolus,GO:0030488//tRNA methylation;GO:0007067//mitotic nuclear division,GO:0000049//tRNA binding;GO:0016428//tRNA (cytosine-5-)-methyltransferase activity;GO:0044822//poly(A) RNA binding,-
54890,0,4,0,13,146,0,0,0,4,0,0,0,"ALKBH5;alkB, alkylation repair homolog 5 (E. coli)",GO:0005634//nucleus;GO:0016607//nuclear speck,GO:0001666//response to hypoxia;GO:0006406//mRNA export from nucleus;GO:0030154//cell differentiation;GO:0006397//mRNA processing;GO:0035553//oxidative single-stranded RNA demethylation;GO:0007283//spermatogenesis,"GO:0035515//oxidative RNA demethylase activity;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",-
54891,1,45,0,84,122,15,0,172,114,45,81,0,INO80D;INO80 complex subunit D,GO:0005634//nucleus,"GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated",-,-
54892,41,0,1,0,0,1,96,0,50,0,0,227,"NCAPG2;non-SMC condensin II complex, subunit G2",GO:0016020//membrane;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0030261//chromosome condensation;GO:0001833//inner cell mass cell proliferation,GO:0035064//methylated histone binding;GO:0005515//protein binding,-
54893,0,735,445,736,926,0,28,650,105,284,1276,13,MTMR10;myotubularin related protein 10,-,GO:0016311//dephosphorylation,GO:0016791//phosphatase activity,K01108//Phosphatidylinositol signaling system;Metabolic pathways;Inositol phosphate metabolism;K01112//Fructose and mannose metabolism
54894,94,0,72,7,0,34,45,0,9,0,24,0,RNF43;ring finger protein 43,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope,GO:0072089//stem cell proliferation;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0038018//Wnt receptor catabolic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005109//frizzled binding,-
54896,0,0,0,0,0,18,5,0,8,0,3,0,PQLC2;PQ loop repeat containing 2,GO:0031301//integral component of organelle membrane;GO:0005765//lysosomal membrane,GO:0003333//amino acid transmembrane transport;GO:0080144//amino acid homeostasis;GO:0015819//lysine transport;GO:0015809//arginine transport,GO:0015189//L-lysine transmembrane transporter activity;GO:0015181//arginine transmembrane transporter activity,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K03247//RNA transport;Measles;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
54897,78,1,0,4,16,47,47,3,86,0,17,2,CASZ1;castor zinc finger 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
54898,0,0,0,0,31,16,57,66,26,0,0,0,ELOVL2;ELOVL fatty acid elongase 2,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0042761//very long-chain fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0044281//small molecule metabolic process",GO:0009922//fatty acid elongase activity;GO:0005515//protein binding,K10205//Fatty acid elongation;Biosynthesis of unsaturated fatty acids
54899,0,0,0,8,7,0,0,0,25,196,18,0,PXK;PX domain containing serine/threonine kinase,GO:0005886//plasma membrane;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043271//negative regulation of ion transport;GO:0032780//negative regulation of ATPase activity;GO:0006954//inflammatory response;GO:0050804//regulation of synaptic transmission;GO:0006468//protein phosphorylation,GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0000166//nucleotide binding;GO:0004672//protein kinase activity;GO:0035091//phosphatidylinositol binding,-
549,0,0,0,13,39,5,18,0,27,0,0,0,AUH;AU RNA binding protein/enoyl-CoA hydratase,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006552//leucine catabolic process;GO:0009083//branched-chain amino acid catabolic process,GO:0004490//methylglutaconyl-CoA hydratase activity;GO:0003730//mRNA 3'-UTR binding;GO:0004300//enoyl-CoA hydratase activity,"K05607//Valine, leucine and isoleucine degradation;Metabolic pathways"
54900,0,0,0,0,0,24,0,0,49,175,2,0,LAX1;lymphocyte transmembrane adaptor 1,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005737//cytoplasm,GO:0042113//B cell activation;GO:0035556//intracellular signal transduction;GO:0000188//inactivation of MAPK activity;GO:0006955//immune response;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048305//immunoglobulin secretion;GO:0050868//negative regulation of T cell activation,GO:0042169//SH2 domain binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
54901,198,0,1,0,21,11,25,34,19,0,6,0,CDKAL1;CDK5 regulatory subunit associated protein 1-like 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005791//rough endoplasmic reticulum,GO:1990145//maintenance of translational fidelity;GO:0035600//tRNA methylthiolation,"GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0035598//N6-threonylcarbomyladenosine methylthiotransferase activity",-
54902,79,45,1,117,191,17,25,477,107,0,97,0,TTC19;tetratricopeptide repeat domain 19,GO:0005813//centrosome;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0030496//midbody,GO:0000910//cytokinesis;GO:0034551//mitochondrial respiratory chain complex III assembly,GO:0005515//protein binding,K10407//Salmonella infection
54903,0,1,0,3,0,34,0,1,27,1,20,1,"MKS1;Meckel syndrome, type 1",GO:0005814//centriole;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0036038//TCTN-B9D complex;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0060271//cilium morphogenesis;GO:0048754//branching morphogenesis of an epithelial tube;GO:0042384//cilium assembly,GO:0005515//protein binding,-
54904,0,13,0,33,120,43,16,0,57,0,0,0,WHSC1L1;Wolf-Hirschhorn syndrome candidate 1-like 1,GO:0005634//nucleus;GO:0005694//chromosome,"GO:0006355//regulation of transcription, DNA-templated;GO:0016571//histone methylation;GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity,K11425//Lysine degradation
54905,0,1,0,0,0,12,0,0,16,0,1,0,"CYP2W1;cytochrome P450, family 2, subfamily W, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,"GO:0020037//heme binding;GO:0004497//monooxygenase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding",-
54906,297,24,0,30,48,19,76,0,69,49,21,154,"FAM208B;family with sequence similarity 208, member B",-,-,-,-
54908,0,0,0,0,0,0,0,41,36,0,0,0,SPDL1;spindle apparatus coiled-coil protein 1,GO:0005829//cytosol;GO:0000940//condensed chromosome outer kinetochore;GO:0005815//microtubule organizing center;GO:0000922//spindle pole;GO:0005634//nucleus,GO:0007080//mitotic metaphase plate congression;GO:0000132//establishment of mitotic spindle orientation;GO:0031577//spindle checkpoint;GO:0034501//protein localization to kinetochore;GO:0000278//mitotic cell cycle,GO:0043515//kinetochore binding;GO:0005515//protein binding;GO:0019899//enzyme binding,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
54910,0,0,0,0,0,34,51,153,0,0,9,0,"SEMA4C;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C",GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0014069//postsynaptic density,GO:0042692//muscle cell differentiation;GO:0021535//cell migration in hindbrain;GO:0071526//semaphorin-plexin signaling pathway;GO:0001843//neural tube closure;GO:0021549//cerebellum development;GO:0032874//positive regulation of stress-activated MAPK cascade,GO:0004872//receptor activity,K06521//Axon guidance
54913,0,0,0,0,1,0,0,0,22,0,0,0,RPP25;ribonuclease P/MRP 25kDa subunit,GO:0005634//nucleus,"GO:0008033//tRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0044822//poly(A) RNA binding;GO:0004526//ribonuclease P activity;GO:0005515//protein binding,K14525//RNA transport;Ribosome biogenesis in eukaryotes
54914,0,52,1,17,54,10,38,0,38,0,1,0,FOCAD;focadhesin,GO:0016021//integral component of membrane;GO:0005925//focal adhesion,-,GO:0005515//protein binding,-
54915,0,0,1,25,145,4,1,48,46,0,0,0,"YTHDF1;YTH domain family, member 1",-,-,GO:0044822//poly(A) RNA binding;GO:1990247//N6-methyladenosine-containing RNA binding,-
54916,0,0,0,0,0,0,24,0,54,0,11,0,TMEM260;transmembrane protein 260,GO:0016021//integral component of membrane,-,-,-
54918,0,32,1,16,38,0,0,0,0,0,0,0,CMTM6;CKLF-like MARVEL transmembrane domain containing 6,GO:0005615//extracellular space;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0006935//chemotaxis,GO:0005125//cytokine activity,-
54919,0,17,15,0,38,18,47,50,81,0,77,0,HEATR2;HEAT repeat containing 2,GO:0005737//cytoplasm,-,-,K12462//Neurotrophin signaling pathway;Vasopressin-regulated water reabsorption
54920,62,0,0,13,41,0,0,95,8,0,53,0,DUS2;dihydrouridine synthase 2,GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process;GO:0060548//negative regulation of cell death;GO:0006469//negative regulation of protein kinase activity;GO:0002943//tRNA dihydrouridine synthesis,GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity;GO:0003725//double-stranded RNA binding;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding,-
54921,0,50,1,10,50,0,64,50,20,0,3,0,"CHTF8;CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)",GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0007049//cell cycle;GO:0006260//DNA replication,GO:0003677//DNA binding,-
54922,0,0,44,0,0,30,19,0,16,0,0,440,RASIP1;Ras interacting protein 1,GO:0005795//Golgi stack;GO:0048471//perinuclear region of cytoplasm,GO:0048754//branching morphogenesis of an epithelial tube;GO:0032319//regulation of Rho GTPase activity;GO:0007165//signal transduction;GO:0001570//vasculogenesis;GO:0010507//negative regulation of autophagy;GO:0001525//angiogenesis,-,K05702//Tight junction;Adherens junction;Leukocyte transendothelial migration
54923,0,0,0,0,17,0,0,0,8,85,0,0,LIME1;Lck interacting transmembrane adaptor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0050852//T cell receptor signaling pathway;GO:0050853//B cell receptor signaling pathway,-,-
54925,0,101,0,51,72,0,18,40,59,0,103,0,ZSCAN32;zinc finger and SCAN domain containing 32,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
54926,0,0,0,1,78,15,0,0,5,0,19,0,UBE2R2;ubiquitin-conjugating enzyme E2R 2,-,GO:0070936//protein K48-linked ubiquitination;GO:0006513//protein monoubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K02207//Herpes simplex infection;Ubiquitin mediated proteolysis
54927,0,0,0,2,39,0,0,0,36,0,12,0,CHCHD3;coiled-coil-helix-coiled-coil-helix domain containing 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane,"GO:0006351//transcription, DNA-templated;GO:0008053//mitochondrial fusion;GO:0007007//inner mitochondrial membrane organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0019902//phosphatase binding;GO:0032947//protein complex scaffold,-
54928,0,0,0,25,53,0,21,0,59,0,20,0,IMPAD1;inositol monophosphatase domain containing 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0046854//phosphatidylinositol phosphorylation;GO:0030204//chondroitin sulfate metabolic process;GO:0002063//chondrocyte development;GO:0042733//embryonic digit morphogenesis;GO:0016311//dephosphorylation;GO:0009791//post-embryonic development;GO:0006021//inositol biosynthetic process;GO:0001958//endochondral ossification,"GO:0052832//inositol monophosphate 3-phosphatase activity;GO:0046872//metal ion binding;GO:0008254//3'-nucleotidase activity;GO:0008441//3'(2'),5'-bisphosphate nucleotidase activity;GO:0008934//inositol monophosphate 1-phosphatase activity;GO:0052833//inositol monophosphate 4-phosphatase activity",K15759//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system;Sulfur metabolism
54929,168,0,0,0,0,18,15,0,10,0,0,1,TMEM161A;transmembrane protein 161A,GO:0016021//integral component of membrane,GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0032526//response to retinoic acid;GO:0045739//positive regulation of DNA repair;GO:0034599//cellular response to oxidative stress;GO:0034644//cellular response to UV,-,-
5493,0,0,0,0,1,0,19,185,57,0,4,0,PPL;periplakin,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030057//desmosome;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0005634//nucleus,GO:0031424//keratinization,GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,-
54930,0,0,0,7,38,18,8,26,17,9,0,0,"HAUS4;HAUS augmin-like complex, subunit 4",GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005874//microtubule;GO:0005819//spindle;GO:0070652//HAUS complex,GO:0051225//spindle assembly;GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization,-,-
54931,0,0,0,20,0,0,0,0,10,0,0,0,TRMT10C;tRNA methyltransferase 10 homolog C (S. cerevisiae),GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005634//nucleus,GO:0008033//tRNA processing;GO:0032259//methylation;GO:0000964//mitochondrial RNA 5'-end processing,GO:0008168//methyltransferase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
54932,0,0,0,0,1,0,0,52,118,0,0,0,EXD3;exonuclease 3'-5' domain containing 3,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K10955//Amoebiasis;Vibrio cholerae infection
54933,0,0,0,0,0,0,0,0,11,0,14,0,"RHBDL2;rhomboid, veinlet-like 2 (Drosophila)",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,K02857//Dorso-ventral axis formation
54934,49,0,0,0,36,29,20,0,13,0,5,265,KANSL2;KAT8 regulatory NSL complex subunit 2,GO:0005654//nucleoplasm;GO:0000123//histone acetyltransferase complex,GO:0006325//chromatin organization;GO:0043984//histone H4-K16 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0043981//histone H4-K5 acetylation,GO:0005515//protein binding;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific),-
54935,0,0,0,0,0,0,0,42,6,0,0,0,DUSP23;dual specificity phosphatase 23,GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
54936,0,0,0,0,0,16,0,0,16,0,0,0,ADPRHL2;ADP-ribosylhydrolase like 2,GO:0005730//nucleolus;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0008152//metabolic process,GO:0004649//poly(ADP-ribose) glycohydrolase activity;GO:0046872//metal ion binding,-
54937,0,0,0,0,0,6,0,0,25,0,0,0,SOHLH2;spermatogenesis and oogenesis specific basic helix-loop-helix 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0048477//oogenesis;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
54938,17,0,0,1,13,54,0,33,11,0,15,80,"SARS2;seryl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process;GO:0010467//gene expression;GO:0006434//seryl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation,GO:0005524//ATP binding;GO:0004828//serine-tRNA ligase activity;GO:0044822//poly(A) RNA binding,K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Arginine and proline metabolism;Biotin metabolism
54939,0,0,1,0,10,0,19,0,44,0,1,0,COMMD4;COMM domain containing 4,GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K09254//Transcriptional misregulation in cancer
5494,0,155,0,61,226,8,49,85,74,0,20,16,"PPM1A;protein phosphatase, Mg2+/Mn2+ dependent, 1A",GO:0005829//cytosol;GO:0043005//neuron projection;GO:0016020//membrane;GO:0005634//nucleus;GO:0005891//voltage-gated calcium channel complex;GO:0005654//nucleoplasm,"GO:0016311//dephosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006499//N-terminal protein myristoylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006470//protein dephosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0016055//Wnt signaling pathway;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0007050//cell cycle arrest",GO:0008022//protein C-terminus binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0070412//R-SMAD binding;GO:0004871//signal transducer activity;GO:0030145//manganese ion binding,K04457//MAPK signaling pathway
54940,0,31,0,12,29,0,17,0,21,0,3,0,OCIAD1;OCIA domain containing 1,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005768//endosome,-,GO:0005515//protein binding,K04006//Hematopoietic cell lineage;Viral myocarditis;Complement and coagulation cascades;K11447//Transcriptional misregulation in cancer;K05767//Adherens junction;Regulation of actin cytoskeleton;K03956//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
54941,155,15,0,0,0,0,0,0,20,0,0,0,"RNF125;ring finger protein 125, E3 ubiquitin protein ligase",-,GO:0045087//innate immune response;GO:0032480//negative regulation of type I interferon production;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K12170//RIG-I-like receptor signaling pathway
54942,0,0,0,0,25,0,0,0,22,0,0,0,"FAM206A;family with sequence similarity 206, member A",GO:0016607//nuclear speck,-,-,-
54943,0,0,0,0,13,0,13,0,4,0,0,0,"DNAJC28;DnaJ (Hsp40) homolog, subfamily C, member 28",-,-,-,K09517//Protein processing in endoplasmic reticulum
54944,0,0,36,0,0,2,1,0,28,0,1,0,LOC54944;uncharacterized LOC54944,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
54946,27,0,0,0,0,11,34,0,30,131,0,0,"SLC41A3;solute carrier family 41, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,GO:0008324//cation transmembrane transporter activity,-
54947,0,0,0,0,0,15,24,0,60,0,9,0,LPCAT2;lysophosphatidylcholine acyltransferase 2,GO:0005789//endoplasmic reticulum membrane;GO:0005795//Golgi stack;GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006663//platelet activating factor biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0061024//membrane organization,GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0005509//calcium ion binding,K13510//Metabolic pathways;Ether lipid metabolism;Glycerophospholipid metabolism
54948,0,0,0,1,11,1,0,90,0,0,0,0,MRPL16;mitochondrial ribosomal protein L16,GO:0005840//ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding,-
54949,0,0,0,16,11,0,0,0,0,0,0,0,SDHAF2;succinate dehydrogenase complex assembly factor 2,GO:0005739//mitochondrion,"GO:0006470//protein dephosphorylation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0018293//protein-FAD linkage;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0006121//mitochondrial electron transport, succinate to ubiquinone",GO:0005515//protein binding,-
5495,91,39,0,4,100,22,0,0,32,0,0,0,"PPM1B;protein phosphatase, Mg2+/Mn2+ dependent, 1B",GO:0016020//membrane;GO:0005829//cytosol,GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0032688//negative regulation of interferon-beta production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050687//negative regulation of defense response to virus;GO:0006499//N-terminal protein myristoylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0006470//protein dephosphorylation,GO:0000287//magnesium ion binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0030145//manganese ion binding,K04461//MAPK signaling pathway
54951,0,0,0,20,0,24,0,0,0,0,15,0,COMMD8;COMM domain containing 8,-,-,GO:0005515//protein binding,-
54952,0,0,0,0,0,10,0,7,0,1,0,0,TRNAU1AP;tRNA selenocysteine 1 associated protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0001514//selenocysteine incorporation,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K13126//RNA degradation;RNA transport;mRNA surveillance pathway
54953,0,0,0,8,0,0,18,0,40,0,0,0,C1orf27;chromosome 1 open reading frame 27,GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity;GO:0008270//zinc ion binding,-
54954,0,0,0,0,0,9,0,0,0,0,6,0,FAM120C;family with sequence similarity 120C,-,-,GO:0044822//poly(A) RNA binding,-
54955,0,0,0,1,45,0,31,0,0,24,0,0,C1orf109;chromosome 1 open reading frame 109,-,-,-,-
54956,0,3,0,3,4,0,0,66,4,0,0,1,"PARP16;poly (ADP-ribose) polymerase family, member 16",GO:0071782//endoplasmic reticulum tubular network;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0070213//protein auto-ADP-ribosylation;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060548//negative regulation of cell death;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006471//protein ADP-ribosylation,GO:0005515//protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0003956//NAD(P)+-protein-arginine ADP-ribosyltransferase activity;GO:0019900//kinase binding;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
54957,0,32,0,8,15,15,0,0,24,0,0,0,TXNL4B;thioredoxin-like 4B,GO:0005681//spliceosomal complex,GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0007067//mitotic nuclear division,-,K12859//Spliceosome
54958,0,0,0,0,0,0,5,0,0,0,0,0,TMEM160;transmembrane protein 160,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,-
54959,0,0,0,0,0,0,23,0,6,0,0,0,"ODAM;odontogenic, ameloblast asssociated",GO:0043205//fibril;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042475//odontogenesis of dentin-containing tooth;GO:0031214//biomineral tissue development,-,-
5496,0,0,0,8,18,0,55,0,20,0,8,0,"PPM1G;protein phosphatase, Mg2+/Mn2+ dependent, 1G",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0007050//cell cycle arrest;GO:0006470//protein dephosphorylation;GO:0035970//peptidyl-threonine dephosphorylation,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,-
54960,0,0,0,0,13,0,0,0,9,0,10,0,GEMIN8;gem (nuclear organelle) associated protein 8,GO:0005730//nucleolus;GO:0034719//SMN-Sm protein complex;GO:0005829//cytosol;GO:0097504//Gemini of coiled bodies;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032797//SMN complex,GO:0000387//spliceosomal snRNP assembly,GO:0005515//protein binding,K13136//RNA transport
54961,0,0,0,0,10,0,0,0,3,0,14,0,SSH3;slingshot protein phosphatase 3,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008064//regulation of actin polymerization or depolymerization;GO:0010591//regulation of lamellipodium assembly;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0050770//regulation of axonogenesis,GO:0003677//DNA binding;GO:0004725//protein tyrosine phosphatase activity;GO:0003779//actin binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,K05766//Regulation of actin cytoskeleton
54962,0,0,0,0,0,0,0,0,0,0,4,0,TIPIN;TIMELESS interacting protein,GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0009411//response to UV;GO:0048478//replication fork protection;GO:0044770//cell cycle phase transition;GO:0000076//DNA replication checkpoint;GO:0031573//intra-S DNA damage checkpoint;GO:0008284//positive regulation of cell proliferation;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
54963,14,0,0,6,1,0,0,38,26,0,1,0,UCKL1;uridine-cytidine kinase 1-like 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0016310//phosphorylation;GO:0044211//CTP salvage;GO:0016032//viral process;GO:0044206//UMP salvage,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004849//uridine kinase activity,K00876//Metabolic pathways;Microbial metabolism in diverse environments;Pyruvate metabolism;Drug metabolism - other enzymes;Pyrimidine metabolism;Aminobenzoate degradation
54964,0,44,68,112,123,0,17,0,16,1,48,0,C1orf56;chromosome 1 open reading frame 56,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005730//nucleolus,-,-,-
54965,0,0,0,8,14,0,0,0,16,0,0,0,"PIGX;phosphatidylinositol glycan anchor biosynthesis, class X",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane,-,K07541//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
54967,0,0,0,0,0,0,3,0,33,0,0,0,CT55;cancer/testis antigen 55,-,-,-,-
54968,0,0,1,12,8,0,0,0,9,0,0,0,TMEM70;transmembrane protein 70,GO:0032592//integral component of mitochondrial membrane;GO:0005743//mitochondrial inner membrane,GO:0033615//mitochondrial proton-transporting ATP synthase complex assembly,-,K02969//Ribosome
54969,0,0,0,11,18,19,0,0,1,0,0,0,C4orf27;chromosome 4 open reading frame 27,GO:0005634//nucleus,-,-,-
54970,29,1,0,7,21,37,0,0,42,0,0,0,TTC12;tetratricopeptide repeat domain 12,-,-,-,K09553//Prion diseases
54971,0,0,0,0,0,15,39,0,5,0,14,0,BANP;BTG3 associated nuclear protein,GO:0005634//nucleus,"GO:0034504//protein localization to nucleus;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0042177//negative regulation of protein catabolic process;GO:0007275//multicellular organismal development;GO:0007049//cell cycle",GO:0005515//protein binding;GO:0002039//p53 binding;GO:0003677//DNA binding,-
54972,8,0,0,0,0,0,0,48,3,0,9,0,TMEM132A;transmembrane protein 132A,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome,-,-,-
54973,0,81,24,40,87,1,19,2,24,0,151,0,CPSF3L;cleavage and polyadenylation specific factor 3-like,GO:0072562//blood microparticle;GO:0032039//integrator complex;GO:0005737//cytoplasm,GO:0016180//snRNA processing,GO:0005515//protein binding;GO:0016787//hydrolase activity,-
54974,0,0,0,1,32,9,0,0,12,0,0,0,THG1L;tRNA-histidine guanylyltransferase 1-like (S. cerevisiae),GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0006400//tRNA modification;GO:0051289//protein homotetramerization;GO:0008033//tRNA processing,GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0008193//tRNA guanylyltransferase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0000049//tRNA binding,-
54976,0,0,0,0,0,13,0,0,19,29,11,0,C20orf27;chromosome 20 open reading frame 27,-,-,-,-
54977,0,46,44,30,91,22,0,69,16,0,49,0,"SLC25A38;solute carrier family 25, member 38",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0030218//erythrocyte differentiation;GO:0006810//transport;GO:0006783//heme biosynthetic process,-,-
54978,0,0,0,0,0,0,0,40,12,0,0,0,"SLC35F6;solute carrier family 35, member F6",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane,GO:0008284//positive regulation of cell proliferation;GO:0006810//transport;GO:1901029//negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
54979,0,0,0,0,0,0,0,0,7,0,0,0,HRASLS2;HRAS-like suppressor 2,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0016042//lipid catabolic process,"GO:0016746//transferase activity, transferring acyl groups;GO:0016787//hydrolase activity",K00678//Retinol metabolism;Vitamin digestion and absorption
5498,0,0,0,0,0,62,12,118,0,0,0,0,PPOX;protoporphyrinogen oxidase,GO:0031966//mitochondrial membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0005758//mitochondrial intermembrane space,GO:0006783//heme biosynthetic process;GO:0042493//response to drug;GO:0055114//oxidation-reduction process;GO:0006778//porphyrin-containing compound metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0044281//small molecule metabolic process,GO:0050660//flavin adenine dinucleotide binding;GO:0004729//oxygen-dependent protoporphyrinogen oxidase activity,K00231//Biosynthesis of secondary metabolites;Metabolic pathways;Porphyrin and chlorophyll metabolism
54980,0,0,0,4,32,19,0,0,0,0,0,0,C2orf42;chromosome 2 open reading frame 42,-,-,-,-
54981,0,0,0,27,48,0,0,0,7,0,5,0,NMRK1;nicotinamide riboside kinase 1,-,GO:0009435//NAD biosynthetic process;GO:0016310//phosphorylation,GO:0046872//metal ion binding;GO:0050262//ribosylnicotinamide kinase activity;GO:0005524//ATP binding,K10524//Nicotinate and nicotinamide metabolism
54982,91,0,0,0,0,0,0,0,6,6,0,0,"CLN6;ceroid-lipofuscinosis, neuronal 6, late infantile, variant",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0031987//locomotion involved in locomotory behavior;GO:0045862//positive regulation of proteolysis;GO:0044265//cellular macromolecule catabolic process;GO:0008203//cholesterol metabolic process;GO:0001573//ganglioside metabolic process;GO:0008219//cell death;GO:0007601//visual perception;GO:0030203//glycosaminoglycan metabolic process;GO:0030163//protein catabolic process;GO:0007042//lysosomal lumen acidification,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
54984,1,0,0,8,0,0,6,0,0,0,0,0,"PINX1;PIN2/TERF1 interacting, telomerase inhibitor 1","GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005730//nucleolus;GO:0000228//nuclear chromosome;GO:0005819//spindle;GO:0000781//chromosome, telomeric region",GO:0051974//negative regulation of telomerase activity;GO:0008285//negative regulation of cell proliferation;GO:0007004//telomere maintenance via telomerase;GO:0007080//mitotic metaphase plate congression,GO:0005515//protein binding;GO:0070034//telomeric RNA binding;GO:0010521//telomerase inhibitor activity,-
54985,0,16,0,13,0,0,0,124,31,0,46,0,HCFC1R1;host cell factor C1 regulator 1 (XPO1 dependent),GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
54986,0,0,0,0,1,26,0,0,37,30,14,0,ULK4;unc-51 like kinase 4,-,GO:0060271//cilium morphogenesis;GO:2001222//regulation of neuron migration;GO:0021591//ventricular system development;GO:0010975//regulation of neuron projection development;GO:0003351//epithelial cilium movement;GO:0006468//protein phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0090036//regulation of protein kinase C signaling;GO:0046328//regulation of JNK cascade;GO:1900744//regulation of p38MAPK cascade;GO:0043408//regulation of MAPK cascade,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K08269//Regulation of autophagy;mTOR signaling pathway;K06228//Hedgehog signaling pathway;Pathways in cancer;Basal cell carcinoma
54987,0,0,0,19,83,0,0,0,18,0,0,0,C1orf123;chromosome 1 open reading frame 123,GO:0070062//extracellular vesicular exosome,-,-,-
54988,7,0,0,0,0,18,21,43,99,0,6,0,ACSM5;acyl-CoA synthetase medium-chain family member 5,GO:0005759//mitochondrial matrix,GO:0006631//fatty acid metabolic process,GO:0047760//butyrate-CoA ligase activity;GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0046872//metal ion binding,K01896//Butanoate metabolism;Lipoic acid metabolism;Metabolic pathways
54989,0,0,0,41,136,0,45,0,31,0,0,0,ZNF770;zinc finger protein 770,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
5499,0,26,0,28,38,0,12,70,0,0,0,0,"PPP1CA;protein phosphatase 1, catalytic subunit, alpha isozyme",GO:0070688//MLL5-L complex;GO:0005634//nucleus;GO:0072357//PTW/PP1 phosphatase complex;GO:0042587//glycogen granule;GO:0005829//cytosol;GO:0043204//perikaryon;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0070062//extracellular vesicular exosome;GO:0000164//protein phosphatase type 1 complex,GO:0019433//triglyceride catabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0048754//branching morphogenesis of an epithelial tube;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0044281//small molecule metabolic process;GO:0007049//cell cycle;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051301//cell division;GO:0005979//regulation of glycogen biosynthetic process;GO:0005981//regulation of glycogen catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0005977//glycogen metabolic process;GO:0042752//regulation of circadian rhythm;GO:0006470//protein dephosphorylation;GO:0030324//lung development,GO:0004722//protein serine/threonine phosphatase activity;GO:0043021//ribonucleoprotein complex binding;GO:0016791//phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K06269//Alcoholism;Long-term potentiation;Dopaminergic synapse;Insulin signaling pathway;Meiosis - yeast;Focal adhesion;mRNA surveillance pathway;Amphetamine addiction;Herpes simplex infection;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Oocyte meiosis
54991,0,0,0,0,0,8,0,0,0,0,0,0,C1orf159;chromosome 1 open reading frame 159,GO:0016021//integral component of membrane,-,-,-
54993,0,1,0,40,29,6,11,38,31,0,10,0,ZSCAN2;zinc finger and SCAN domain containing 2,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
54994,0,27,1,12,44,0,44,0,14,0,0,0,GID8;GID complex subunit 8,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0030054//cell junction,-,-,-
54995,0,0,0,0,0,0,0,0,8,0,0,0,"OXSM;3-oxoacyl-ACP synthase, mitochondrial",GO:0005739//mitochondrion,GO:0006637//acyl-CoA metabolic process;GO:0051790//short-chain fatty acid biosynthetic process;GO:0051792//medium-chain fatty acid biosynthetic process,GO:0004315//3-oxoacyl-[acyl-carrier-protein] synthase activity,K09458//Metabolic pathways;Fatty acid biosynthesis
54996,0,50,0,17,0,0,0,85,40,0,31,0,MARC2;mitochondrial amidoxime reducing component 2,GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0005743//mitochondrial inner membrane,GO:0051410//detoxification of nitrogen compound;GO:0055114//oxidation-reduction process;GO:0042126//nitrate metabolic process,GO:0043546//molybdopterin cofactor binding;GO:0030151//molybdenum ion binding;GO:0008940//nitrate reductase activity;GO:0030170//pyridoxal phosphate binding,-
54997,0,0,22,0,14,0,0,62,11,0,10,0,TESC;tescalcin,GO:0005886//plasma membrane;GO:0032587//ruffle membrane;GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030027//lamellipodium,"GO:0072661//protein targeting to plasma membrane;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0030154//cell differentiation;GO:0030854//positive regulation of granulocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0006469//negative regulation of protein kinase activity;GO:0071300//cellular response to retinoic acid;GO:0043086//negative regulation of catalytic activity;GO:0051604//protein maturation;GO:0050821//protein stabilization;GO:0010628//positive regulation of gene expression;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0008285//negative regulation of cell proliferation",GO:0000287//magnesium ion binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0019212//phosphatase inhibitor activity;GO:0004860//protein kinase inhibitor activity;GO:0042803//protein homodimerization activity,K06268//Glutamatergic synapse;Apoptosis;T cell receptor signaling pathway;Amphetamine addiction;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;Tuberculosis;Long-term potentiation;Axon guidance;VEGF signaling pathway;Osteoclast differentiation;Alzheimer's disease;Calcium signaling pathway;B cell receptor signaling pathway;HTLV-I infection
54998,0,0,1,0,14,0,0,0,0,0,0,0,AURKAIP1;aurora kinase A interacting protein 1,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0045839//negative regulation of mitosis;GO:0045862//positive regulation of proteolysis,GO:0005515//protein binding,-
55,0,575,1,652,1632,2,19,2,25,0,9,0,"ACPP;acid phosphatase, prostate",GO:0005765//lysosomal membrane;GO:0045177//apical part of cell;GO:0030175//filopodium;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0031985//Golgi cisterna;GO:0005771//multivesicular body;GO:0005622//intracellular;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0012506//vesicle membrane,GO:0009117//nucleotide metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0060168//positive regulation of adenosine receptor signaling pathway;GO:0016311//dephosphorylation;GO:0046085//adenosine metabolic process;GO:0006772//thiamine metabolic process;GO:0051930//regulation of sensory perception of pain,GO:0042802//identical protein binding;GO:0042131//thiamine phosphate phosphatase activity;GO:0016791//phosphatase activity;GO:0003993//acid phosphatase activity;GO:0033265//choline binding;GO:0042803//protein homodimerization activity;GO:0052642//lysophosphatidic acid phosphatase activity;GO:0008253//5'-nucleotidase activity,K14410//Riboflavin metabolism;Lysosome
550,0,0,0,8,0,7,40,0,0,0,0,0,AUP1;ancient ubiquitous protein 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,-,GO:0005515//protein binding,K10636//Protein processing in endoplasmic reticulum;K14022//Protein processing in endoplasmic reticulum
5500,0,578,7,726,2289,0,38,30,17,0,0,0,"PPP1CB;protein phosphatase 1, catalytic subunit, beta isozyme",GO:0070062//extracellular vesicular exosome;GO:0000164//protein phosphatase type 1 complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0072357//PTW/PP1 phosphatase complex;GO:0042587//glycogen granule;GO:0005634//nucleus;GO:0070688//MLL5-L complex,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0051301//cell division;GO:0019433//triglyceride catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0005981//regulation of glycogen catabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0005979//regulation of glycogen biosynthetic process;GO:0005977//glycogen metabolic process;GO:0042752//regulation of circadian rhythm;GO:0030155//regulation of cell adhesion;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0006470//protein dephosphorylation,GO:0016791//phosphatase activity;GO:0017018//myosin phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0050115//myosin-light-chain-phosphatase activity;GO:0019901//protein kinase binding,K06269//Amphetamine addiction;Herpes simplex infection;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Oocyte meiosis;Focal adhesion;mRNA surveillance pathway;Dopaminergic synapse;Insulin signaling pathway;Meiosis - yeast;Alcoholism;Long-term potentiation
55001,0,0,0,0,2,0,43,0,0,0,26,0,TTC22;tetratricopeptide repeat domain 22,-,-,-,K01881//Aminoacyl-tRNA biosynthesis
55002,0,0,0,21,35,9,1,43,48,0,0,0,TMCO3;transmembrane and coiled-coil domains 3,GO:0016021//integral component of membrane,GO:1902600//hydrogen ion transmembrane transport,GO:0015299//solute:proton antiporter activity,-
55003,0,32,2,49,102,0,11,71,32,0,0,0,PAK1IP1;PAK1 interacting protein 1,GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0008283//cell proliferation;GO:0009968//negative regulation of signal transduction;GO:0060021//palate development,-,-
55004,0,93,0,8,50,0,0,1,10,0,3,0,"LAMTOR1;late endosomal/lysosomal adaptor, MAPK and MTOR activator 1",GO:0005765//lysosomal membrane;GO:0045121//membrane raft;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005764//lysosome;GO:0031902//late endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0071986//Ragulator complex,GO:0034613//cellular protein localization;GO:0007040//lysosome organization;GO:0042632//cholesterol homeostasis;GO:0032439//endosome localization;GO:0001919//regulation of receptor recycling;GO:0010872//regulation of cholesterol esterification;GO:0071230//cellular response to amino acid stimulus;GO:0043410//positive regulation of MAPK cascade;GO:0016049//cell growth;GO:0060620//regulation of cholesterol import;GO:0032418//lysosome localization;GO:0032008//positive regulation of TOR signaling;GO:0007032//endosome organization;GO:0043547//positive regulation of GTPase activity;GO:0010874//regulation of cholesterol efflux,GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032947//protein complex scaffold,-
55005,0,0,0,0,13,1,0,0,0,0,0,0,RMND1;required for meiotic nuclear division 1 homolog (S. cerevisiae),GO:0005739//mitochondrion,GO:0006412//translation,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01920//Glutathione metabolism;Metabolic pathways
55006,0,0,0,1,31,24,0,1,19,0,0,0,TRMT61B;tRNA methyltransferase 61 homolog B (S. cerevisiae),GO:0005739//mitochondrion;GO:0031515//tRNA (m1A) methyltransferase complex,GO:0070901//mitochondrial tRNA methylation;GO:0051260//protein homooligomerization,GO:0016429//tRNA (adenine-N1-)-methyltransferase activity;GO:0005515//protein binding,K08694//Oocyte meiosis;Progesterone-mediated oocyte maturation
55007,7,0,0,12,36,0,10,0,0,0,0,0,"FAM118A;family with sequence similarity 118, member A",GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
55008,9,21,2,28,89,1,36,0,30,102,16,0,HERC6;HECT and RLD domain containing E3 ubiquitin protein ligase family member 6,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0002244//hematopoietic progenitor cell differentiation;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,K10615//Ubiquitin mediated proteolysis
55009,0,0,0,0,0,0,0,0,0,0,7,409,C19orf24;chromosome 19 open reading frame 24,GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm,-,-,-
5501,0,77,1,68,164,0,0,0,9,0,8,0,"PPP1CC;protein phosphatase 1, catalytic subunit, gamma isozyme",GO:0005634//nucleus;GO:0070688//MLL5-L complex;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0072357//PTW/PP1 phosphatase complex;GO:0016607//nuclear speck;GO:0005739//mitochondrion;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0000777//condensed chromosome kinetochore;GO:0032154//cleavage furrow,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0030182//neuron differentiation;GO:0006470//protein dephosphorylation;GO:0032922//circadian regulation of gene expression;GO:0019433//triglyceride catabolic process;GO:0043153//entrainment of circadian clock by photoperiod;GO:0000278//mitotic cell cycle;GO:0005977//glycogen metabolic process;GO:0051301//cell division;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0044281//small molecule metabolic process,GO:0004722//protein serine/threonine phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019901//protein kinase binding;GO:0004721//phosphoprotein phosphatase activity;GO:0016791//phosphatase activity,K06269//Meiosis - yeast;Insulin signaling pathway;Dopaminergic synapse;Long-term potentiation;Alcoholism;Oocyte meiosis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Herpes simplex infection;Amphetamine addiction;mRNA surveillance pathway;Focal adhesion
55010,0,0,0,0,0,16,0,1,60,0,0,0,PARPBP;PARP1 binding protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000785//chromatin,GO:0006281//DNA repair;GO:2000042//negative regulation of double-strand break repair via homologous recombination,GO:0003677//DNA binding;GO:0005515//protein binding,-
55011,0,0,1,4,10,0,0,0,24,1,0,0,PIH1D1;PIH1 domain containing 1,GO:0070761//pre-snoRNP complex,GO:0000492//box C/D snoRNP assembly;GO:0030855//epithelial cell differentiation,-,-
550113,0,0,0,0,0,0,0,0,3,0,0,0,LOC550113;uncharacterized LOC550113,-,-,-,K15290//Synaptic vesicle cycle
55012,0,36,0,24,106,0,2,26,11,0,27,0,"PPP2R3C;protein phosphatase 2, regulatory subunit B'', gamma",GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,GO:0032147//activation of protein kinase activity;GO:0001782//B cell homeostasis;GO:0043029//T cell homeostasis;GO:0048536//spleen development;GO:0045579//positive regulation of B cell differentiation;GO:0002759//regulation of antimicrobial humoral response;GO:0051900//regulation of mitochondrial depolarization,GO:0005509//calcium ion binding,K11583//Dopaminergic synapse;mRNA surveillance pathway
55013,0,0,0,0,0,16,18,0,8,0,0,0,CCDC109B;coiled-coil domain containing 109B,GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane;GO:0031224//intrinsic component of membrane;GO:1990246//uniplex complex;GO:0034704//calcium channel complex,GO:0006851//mitochondrial calcium ion transport;GO:0051560//mitochondrial calcium ion homeostasis,GO:0005216//ion channel activity;GO:0019855//calcium channel inhibitor activity,-
55014,0,96,0,78,100,25,34,12,53,0,14,0,STX17;syntaxin 17,GO:0005765//lysosomal membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0031201//SNARE complex;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0016021//integral component of membrane;GO:0030134//ER to Golgi transport vesicle;GO:0000421//autophagic vacuole membrane;GO:0030868//smooth endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0007030//Golgi organization;GO:0097111//endoplasmic reticulum-Golgi intermediate compartment organization;GO:0006887//exocytosis;GO:0034497//protein localization to pre-autophagosomal structure;GO:0000046//autophagic vacuole fusion,GO:0019901//protein kinase binding;GO:0005484//SNAP receptor activity;GO:0000149//SNARE binding;GO:0019903//protein phosphatase binding,K08491//SNARE interactions in vesicular transport
55015,0,1,0,0,16,7,63,0,0,0,0,224,PRPF39;pre-mRNA processing factor 39,GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,-,-
55016,1,0,0,0,0,25,0,0,33,0,0,0,"MARCH1;membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase",GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005764//lysosome;GO:0031902//late endosome membrane,GO:0000209//protein polyubiquitination;GO:0006955//immune response;GO:0002495//antigen processing and presentation of peptide antigen via MHC class II,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0042287//MHC protein binding,-
55017,0,0,0,17,41,0,0,0,13,0,0,0,C14orf119;chromosome 14 open reading frame 119,GO:0005739//mitochondrion,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
5502,0,0,0,0,0,0,20,67,0,0,23,0,"PPP1R1A;protein phosphatase 1, regulatory (inhibitor) subunit 1A",GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0043086//negative regulation of catalytic activity;GO:0005977//glycogen metabolic process;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0004865//protein serine/threonine phosphatase inhibitor activity,K08050//Long-term potentiation
55020,0,0,0,9,10,0,12,57,40,0,0,0,TTC38;tetratricopeptide repeat domain 38,GO:0070062//extracellular vesicular exosome,-,-,-
55022,0,0,6,1,0,0,13,45,2,0,0,0,PID1;phosphotyrosine interaction domain containing 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0071356//cellular response to tumor necrosis factor;GO:0010635//regulation of mitochondrial fusion;GO:2001274//negative regulation of glucose import in response to insulin stimulus;GO:0071345//cellular response to cytokine stimulus;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0071398//cellular response to fatty acid;GO:0006112//energy reserve metabolic process;GO:0070346//positive regulation of fat cell proliferation;GO:0044320//cellular response to leptin stimulus;GO:0071354//cellular response to interleukin-6;GO:0051881//regulation of mitochondrial membrane potential;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2001171//positive regulation of ATP biosynthetic process;GO:0070584//mitochondrion morphogenesis;GO:2001170//negative regulation of ATP biosynthetic process;GO:0010628//positive regulation of gene expression;GO:0090298//negative regulation of mitochondrial DNA replication;GO:0001933//negative regulation of protein phosphorylation,-,-
55023,12,4,1,88,362,3,26,68,105,29,12,0,PHIP;pleckstrin homology domain interacting protein,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0006606//protein import into nucleus;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0022604//regulation of cell morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0045840//positive regulation of mitosis;GO:0040008//regulation of growth;GO:0008286//insulin receptor signaling pathway;GO:0001932//regulation of protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043066//negative regulation of apoptotic process",GO:0005515//protein binding;GO:0070577//lysine-acetylated histone binding;GO:0005158//insulin receptor binding,-
55024,58,0,0,26,20,0,0,0,28,0,9,0,BANK1;B-cell scaffold protein with ankyrin repeats 1,-,GO:0042113//B cell activation,-,K12230//B cell receptor signaling pathway
55026,0,0,0,4,0,21,0,0,21,0,0,0,TMEM255A;transmembrane protein 255A,GO:0016021//integral component of membrane,-,-,-
55027,0,0,0,4,15,1,0,0,24,0,0,0,HEATR3;HEAT repeat containing 3,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
55028,56,44,18,12,90,0,0,87,18,0,54,1,C17orf80;chromosome 17 open reading frame 80,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,K02130//Oxidative phosphorylation;Metabolic pathways
55030,0,0,0,54,22,0,24,0,38,0,26,1,FBXO34;F-box protein 34,-,-,-,-
55031,0,25,0,43,192,77,14,0,62,0,6,0,USP47;ubiquitin specific peptidase 47,GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex,"GO:0006284//base-excision repair;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0042493//response to drug;GO:0010972//negative regulation of G2/M transition of mitotic cell cycle;GO:0034644//cellular response to UV;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030307//positive regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0035520//monoubiquitinated protein deubiquitination",GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0071987//WD40-repeat domain binding,-
55032,0,24,0,24,24,1,0,0,27,0,0,0,"SLC35A5;solute carrier family 35, member A5",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:1901679//nucleotide transmembrane transport;GO:0015992//proton transport;GO:0015780//nucleotide-sugar transport;GO:0008643//carbohydrate transport,GO:0005338//nucleotide-sugar transmembrane transporter activity;GO:0005351//sugar:proton symporter activity,-
55033,0,0,0,13,0,3,0,0,26,0,12,0,"FKBP14;FK506 binding protein 14, 22 kDa",GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0000413//protein peptidyl-prolyl isomerization;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0061077//chaperone-mediated protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005509//calcium ion binding;GO:0005528//FK506 binding,-
55034,0,0,0,0,0,0,0,101,14,0,13,0,MOCOS;molybdenum cofactor sulfurase,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0006766//vitamin metabolic process,GO:0030151//molybdenum ion binding;GO:0016829//lyase activity;GO:0016740//transferase activity;GO:0008265//Mo-molybdopterin cofactor sulfurase activity;GO:0030170//pyridoxal phosphate binding,-
55035,0,0,1,11,47,34,4,0,5,0,0,0,NOL8;nucleolar protein 8,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0030307//positive regulation of cell growth;GO:0006364//rRNA processing;GO:0006260//DNA replication,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K01870//Flagellar assembly;Aminoacyl-tRNA biosynthesis
55036,47,42,43,26,52,8,0,89,48,0,56,0,CCDC40;coiled-coil domain containing 40,GO:0005737//cytoplasm;GO:0005929//cilium,GO:0003351//epithelial cilium movement;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0035469//determination of pancreatic left/right asymmetry;GO:0003356//regulation of cilium beat frequency;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry;GO:0070286//axonemal dynein complex assembly;GO:0001947//heart looping;GO:0030324//lung development,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
55037,0,32,1,14,32,22,21,49,57,0,19,0,PTCD3;pentatricopeptide repeat domain 3,GO:0005739//mitochondrion,GO:0006417//regulation of translation;GO:0032543//mitochondrial translation,GO:0044822//poly(A) RNA binding;GO:0043024//ribosomal small subunit binding;GO:0019843//rRNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
55039,0,2,33,5,13,0,0,0,16,0,0,0,TRMT12;tRNA methyltransferase 12 homolog (S. cerevisiae),-,GO:0008033//tRNA processing,GO:0016740//transferase activity,-
5504,0,48,1,46,66,0,16,0,41,0,0,0,"PPP1R2;protein phosphatase 1, regulatory (inhibitor) subunit 2",-,GO:0009966//regulation of signal transduction;GO:0006091//generation of precursor metabolites and energy;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0043086//negative regulation of catalytic activity;GO:0005977//glycogen metabolic process,GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0005515//protein binding,K12489//Endocytosis
55040,0,1,0,4,11,0,37,0,25,0,1,0,EPN3;epsin 3,GO:0070062//extracellular vesicular exosome;GO:0030136//clathrin-coated vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0019897//extrinsic component of plasma membrane;GO:0005905//coated pit,-,GO:0005515//protein binding;GO:0008289//lipid binding,K12471//Endocytosis
55041,0,70,8,140,310,0,0,44,90,0,1,217,"PLEKHB2;pleckstrin homology domain containing, family B (evectins) member 2",GO:0055038//recycling endosome membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
55048,1,0,0,0,1,0,0,0,31,0,0,0,VPS37C;vacuolar protein sorting 37 homolog C (S. cerevisiae),GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0000813//ESCRT I complex;GO:0031902//late endosome membrane,GO:0019082//viral protein processing;GO:0061024//membrane organization;GO:0019068//virion assembly;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0016032//viral process;GO:0019058//viral life cycle,-,K12185//Endocytosis
55049,0,0,0,9,0,0,9,5,0,76,0,0,C19orf60;chromosome 19 open reading frame 60,-,-,GO:0005515//protein binding,-
55051,0,0,0,8,0,0,0,0,5,0,0,280,"NRDE2;NRDE-2, necessary for RNA interference, domain containing",-,-,-,-
55052,0,0,29,0,56,0,0,0,0,0,0,0,MRPL20;mitochondrial ribosomal protein L20,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0019843//rRNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
55054,0,26,0,5,45,0,0,55,0,0,18,0,ATG16L1;autophagy related 16-like 1 (S. cerevisiae),GO:0005930//axoneme;GO:0005776//autophagic vacuole;GO:0000421//autophagic vacuole membrane;GO:0034045//pre-autophagosomal structure membrane,GO:0015031//protein transport;GO:0051260//protein homooligomerization;GO:0000045//autophagic vacuole assembly;GO:0039689//negative stranded viral RNA replication,GO:0042802//identical protein binding;GO:0005515//protein binding,K12857//Spliceosome
55055,0,0,0,9,36,0,15,57,20,0,0,0,ZWILCH;zwilch kinetochore protein,GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007093//mitotic cell cycle checkpoint,GO:0005515//protein binding,-
55057,0,0,0,0,10,0,55,0,46,0,9,0,AIM1L;absent in melanoma 1-like,-,-,GO:0030246//carbohydrate binding,-
5506,0,0,0,0,0,0,0,0,4,0,0,0,"PPP1R3A;protein phosphatase 1, regulatory subunit 3A",GO:0016021//integral component of membrane,GO:0005977//glycogen metabolic process,-,K07189//Insulin signaling pathway
55061,0,0,0,0,8,0,3,0,37,0,0,0,SUSD4;sushi domain containing 4,GO:0016021//integral component of membrane,-,-,K03906//Complement and coagulation cascades;K04012//Hematopoietic cell lineage;Epstein-Barr virus infection;Complement and coagulation cascades;B cell receptor signaling pathway;K04004//Complement and coagulation cascades;Staphylococcus aureus infection
55062,0,0,2,0,50,0,0,155,11,0,3,0,"WIPI1;WD repeat domain, phosphoinositide interacting 1",GO:0000421//autophagic vacuole membrane;GO:0030136//clathrin-coated vesicle;GO:0034045//pre-autophagosomal structure membrane;GO:0000139//Golgi membrane;GO:0010008//endosome membrane;GO:0000407//pre-autophagosomal structure;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,"GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006914//autophagy;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0048203//vesicle targeting, trans-Golgi to endosome","GO:0030331//estrogen receptor binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0050681//androgen receptor binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005102//receptor binding",-
55063,0,15,0,0,1,9,12,0,17,72,23,0,"ZCWPW1;zinc finger, CW type with PWWP domain 1",-,-,GO:0008270//zinc ion binding,K11424//Lysine degradation;Transcriptional misregulation in cancer
550631,0,174,51,89,136,0,27,227,36,1,192,305,CCDC157;coiled-coil domain containing 157,-,-,-,-
55064,0,0,0,8,38,0,0,0,18,0,0,0,SPATA6L;spermatogenesis associated 6-like,-,-,-,-
550643,0,21,0,6,44,0,0,0,0,0,6,0,LINC01420;long intergenic non-protein coding RNA 1420,-,-,-,-
55065,0,0,0,0,1,0,0,0,10,0,0,0,"SLC52A1;solute carrier family 52 (riboflavin transporter), member 1",GO:0005887//integral component of plasma membrane,GO:0032218//riboflavin transport;GO:0009615//response to virus,GO:0001618//virus receptor activity;GO:0032217//riboflavin transporter activity,K14620//Vitamin digestion and absorption
55066,0,0,0,5,0,48,77,59,86,0,29,0,PDPR;pyruvate dehydrogenase phosphatase regulatory subunit,GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,GO:0006546//glycine catabolic process;GO:0055114//oxidation-reduction process;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process;GO:0032259//methylation,GO:0016491//oxidoreductase activity;GO:0004047//aminomethyltransferase activity,"K00314//Metabolic pathways;Glycine, serine and threonine metabolism"
55068,0,0,0,0,0,12,25,0,34,0,5,0,ENOX1;ecto-NOX disulfide-thiol exchanger 1,GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0055114//oxidation-reduction process;GO:0048511//rhythmic process,GO:0000166//nucleotide binding;GO:0016491//oxidoreductase activity;GO:0003676//nucleic acid binding,-
55069,1,22,0,14,27,0,36,0,17,0,0,0,TMEM248;transmembrane protein 248,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K12662//Spliceosome
5507,0,26,0,0,0,0,0,0,0,0,0,0,"PPP1R3C;protein phosphatase 1, regulatory subunit 3C",GO:0005829//cytosol,GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0016311//dephosphorylation;GO:0005975//carbohydrate metabolic process,GO:0005515//protein binding;GO:0019903//protein phosphatase binding;GO:0004722//protein serine/threonine phosphatase activity,K07189//Insulin signaling pathway
55070,0,0,0,0,0,0,0,73,23,160,4,0,DET1;de-etiolated homolog 1 (Arabidopsis),GO:0005634//nucleus,-,-,K10571//Ubiquitin mediated proteolysis
55071,0,0,0,0,0,0,0,0,25,0,0,0,C9orf40;chromosome 9 open reading frame 40,-,-,-,-
55072,75,28,1,1,5,0,0,0,0,0,14,0,RNF31;ring finger protein 31,GO:0005737//cytoplasm;GO:0071797//LUBAC complex;GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050852//T cell receptor signaling pathway;GO:0097039//protein linear polyubiquitination;GO:0000209//protein polyubiquitination;GO:0023035//CD40 signaling pathway,GO:0043130//ubiquitin binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,-
55073,0,62,12,23,117,9,24,7,25,58,43,0,"LRRC37A4P;leucine rich repeat containing 37, member A4, pseudogene",-,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
55074,0,1,0,58,38,41,19,0,14,161,0,0,OXR1;oxidation resistance 1,GO:0005739//mitochondrion;GO:0005730//nucleolus,GO:0071447//cellular response to hydroperoxide;GO:0055114//oxidation-reduction process;GO:0043524//negative regulation of neuron apoptotic process;GO:0006979//response to oxidative stress;GO:0007628//adult walking behavior,GO:0016491//oxidoreductase activity,K12587//RNA degradation;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
55075,0,0,0,0,2,5,44,0,25,0,0,0,UACA;uveal autoantigen with coiled-coil domains and ankyrin repeats,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005635//nuclear envelope;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0043293//apoptosome,GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042307//positive regulation of protein import into nucleus;GO:0043065//positive regulation of apoptotic process;GO:0050728//negative regulation of inflammatory response;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009411//response to UV,GO:0005515//protein binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
55076,0,0,0,0,0,0,0,0,6,0,0,0,TMEM45A;transmembrane protein 45A,GO:0016021//integral component of membrane,-,-,-
55079,0,0,0,0,0,20,0,127,22,0,0,0,FEZF2;FEZ family zinc finger 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021797//forebrain anterior/posterior pattern specification;GO:0007411//axon guidance;GO:0008285//negative regulation of cell proliferation;GO:0021542//dentate gyrus development;GO:0007626//locomotory behavior;GO:0007413//axonal fasciculation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0016358//dendrite development;GO:0045666//positive regulation of neuron differentiation",GO:0046872//metal ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
55080,0,1,0,0,14,0,0,12,20,0,0,0,TAPBPL;TAP binding protein-like,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0002590//negative regulation of antigen processing and presentation of peptide antigen via MHC class I,GO:0032403//protein complex binding,K08058//Antigen processing and presentation
55081,0,1,0,65,184,0,0,0,0,0,0,0,IFT57;intraflagellar transport 57,GO:0030992//intraciliary transport particle B;GO:0005794//Golgi apparatus;GO:0044292//dendrite terminus;GO:0036064//ciliary basal body;GO:0005929//cilium;GO:0005813//centrosome;GO:0032391//photoreceptor connecting cilium,"GO:0042981//regulation of apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007224//smoothened signaling pathway;GO:0001843//neural tube closure;GO:0006355//regulation of transcription, DNA-templated;GO:0050680//negative regulation of epithelial cell proliferation;GO:0042073//intraciliary transport;GO:0001947//heart looping;GO:0006351//transcription, DNA-templated;GO:0060972//left/right pattern formation;GO:0006915//apoptotic process;GO:0042384//cilium assembly",GO:0003677//DNA binding;GO:0005515//protein binding,K04638//Huntington's disease
55082,0,0,0,3,9,0,0,0,17,0,0,0,ARGLU1;arginine and glutamate rich 1,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
55083,0,0,0,0,0,24,45,0,69,98,12,0,KIF26B;kinesin family member 26B,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005871//kinesin complex,GO:0007018//microtubule-based movement;GO:0072092//ureteric bud invasion;GO:0030010//establishment of cell polarity;GO:0022409//positive regulation of cell-cell adhesion;GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding,-
55084,0,0,0,0,0,34,23,0,36,0,11,0,SOBP;sine oculis binding protein homolog (Drosophila),-,GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis,GO:0032184//SUMO polymer binding;GO:0046872//metal ion binding,-
55086,0,0,0,0,0,15,0,0,20,0,0,0,CXorf57;chromosome X open reading frame 57,-,-,GO:0044822//poly(A) RNA binding,-
55088,120,50,0,56,179,12,28,0,47,0,1,0,CCDC186;coiled-coil domain containing 186,-,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
55089,0,0,0,0,0,5,23,0,76,0,0,0,"SLC38A4;solute carrier family 38, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0055085//transmembrane transport,GO:0015171//amino acid transmembrane transporter activity;GO:0015293//symporter activity,-
5509,0,0,1,23,98,7,0,1,49,0,0,0,"PPP1R3D;protein phosphatase 1, regulatory subunit 3D",GO:0042587//glycogen granule;GO:0043231//intracellular membrane-bounded organelle,GO:0016311//dephosphorylation;GO:0005977//glycogen metabolic process;GO:0005981//regulation of glycogen catabolic process;GO:0005979//regulation of glycogen biosynthetic process,GO:0004722//protein serine/threonine phosphatase activity;GO:0019899//enzyme binding,K07189//Insulin signaling pathway
55090,0,0,0,0,0,0,0,0,19,0,0,0,MED9;mediator complex subunit 9,GO:0016592//mediator complex,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity,-
55092,0,0,0,0,20,0,9,0,49,0,0,0,TMEM51;transmembrane protein 51,GO:0016021//integral component of membrane,-,-,-
55093,0,0,0,12,3,0,0,0,8,0,0,0,WDYHV1;WDYHV motif containing 1,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006464//cellular protein modification process,GO:0070773//protein-N-terminal glutamine amidohydrolase activity;GO:0005515//protein binding,-
55094,0,0,1,9,8,36,0,70,54,0,7,0,GPATCH1;G patch domain containing 1,GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome",GO:0003676//nucleic acid binding,-
55095,0,24,0,0,31,7,16,44,52,0,6,0,SAMD4B;sterile alpha motif domain containing 4B,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding,-
55096,0,0,0,0,0,0,0,0,24,0,0,0,EBLN2;endogenous Bornavirus-like nucleoprotein 2,-,-,-,-
5510,1,45,1,83,99,11,0,183,17,52,46,0,"PPP1R7;protein phosphatase 1, regulatory subunit 7",GO:0070062//extracellular vesicular exosome;GO:0005694//chromosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050790//regulation of catalytic activity;GO:0035307//positive regulation of protein dephosphorylation,GO:0030234//enzyme regulator activity;GO:0008599//protein phosphatase type 1 regulator activity,-
55100,0,0,0,11,14,14,51,0,2,134,6,0,WDR70;WD repeat domain 70,-,-,GO:0019899//enzyme binding,K12857//Spliceosome
55101,9,1,0,17,9,0,0,0,2,0,33,0,ATP5SL;ATP5S-like,GO:0005739//mitochondrion,-,-,-
55102,70,1,0,83,150,17,0,36,77,0,1,0,ATG2B;autophagy related 2B,GO:0000407//pre-autophagosomal structure;GO:0005811//lipid particle;GO:0034045//pre-autophagosomal structure membrane;GO:0019898//extrinsic component of membrane,GO:0000422//mitochondrion degradation;GO:0006995//cellular response to nitrogen starvation;GO:0000045//autophagic vacuole assembly,-,-
55103,0,7,0,22,110,18,87,30,71,0,9,0,RALGPS2;Ral GEF with PH domain and SH3 binding motif 2,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005085//guanyl-nucleotide exchange factor activity,K04349//MAPK signaling pathway;Focal adhesion
55105,0,0,0,1,9,8,22,0,0,0,0,0,GPATCH2;G patch domain containing 2,-,GO:0010923//negative regulation of phosphatase activity,GO:0003676//nucleic acid binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
55106,0,0,0,0,0,0,0,0,0,0,9,0,SLFN12;schlafen family member 12,-,-,GO:0005524//ATP binding,-
55107,93,0,0,0,0,11,22,19,69,1,0,1,"ANO1;anoctamin 1, calcium activated chloride channel",GO:0034707//chloride channel complex;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0060438//trachea development;GO:0006812//cation transport;GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006821//chloride transport;GO:0042391//regulation of membrane potential;GO:0055085//transmembrane transport,GO:0005227//calcium activated cation channel activity;GO:0005229//intracellular calcium activated chloride channel activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,-
55109,82,1,1,26,47,10,0,28,30,0,0,0,AGGF1;angiogenic factor with G patch and FHA domains 1,GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0001938//positive regulation of endothelial cell proliferation;GO:0001570//vasculogenesis;GO:0007155//cell adhesion;GO:0001525//angiogenesis;GO:0045766//positive regulation of angiogenesis;GO:0006396//RNA processing,GO:0003676//nucleic acid binding;GO:0005515//protein binding,-
5511,0,27,1,26,44,0,36,0,22,0,9,0,"PPP1R8;protein phosphatase 1, regulatory subunit 8",GO:0016607//nuclear speck;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0008283//cell proliferation;GO:0043086//negative regulation of catalytic activity;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0006401//RNA catabolic process",GO:0004519//endonuclease activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004865//protein serine/threonine phosphatase inhibitor activity;GO:0008599//protein phosphatase type 1 regulator activity;GO:0003723//RNA binding;GO:0008995//ribonuclease E activity,-
55111,0,41,0,0,0,0,0,0,1,0,0,0,"PLEKHJ1;pleckstrin homology domain containing, family J member 1",-,-,-,K01109//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
55112,0,31,0,22,3,0,0,0,41,0,0,0,WDR60;WD repeat domain 60,GO:0005929//cilium;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0030030//cell projection organization,-,K10415//Phagosome;Vasopressin-regulated water reabsorption;Salmonella infection
55113,45,0,0,0,22,0,12,134,3,0,5,0,"XKR8;XK, Kell blood group complex subunit-related family, member 8",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0043652//engulfment of apoptotic cell;GO:0070782//phosphatidylserine exposure on apoptotic cell surface,-,-
55114,0,1,0,8,20,0,0,0,50,0,3,0,ARHGAP17;Rho GTPase activating protein 17,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0005096//GTPase activator activity,K05732//Regulation of actin cytoskeleton;Focal adhesion;Leukocyte transendothelial migration;K07526//Axon guidance;K13709//Focal adhesion;Leukocyte transendothelial migration
55116,105,0,0,0,0,0,0,58,12,87,9,0,TMEM39B;transmembrane protein 39B,GO:0016021//integral component of membrane,-,-,-
55117,0,0,0,0,0,30,64,0,10,0,4,0,"SLC6A15;solute carrier family 6 (neutral amino acid transporter), member 15",GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006836//neurotransmitter transport;GO:0006865//amino acid transport;GO:0006814//sodium ion transport;GO:0015820//leucine transport;GO:0055085//transmembrane transport;GO:0015804//neutral amino acid transport;GO:0015824//proline transport;GO:0006811//ion transport;GO:0035524//proline transmembrane transport,GO:0005328//neurotransmitter:sodium symporter activity;GO:0005326//neurotransmitter transporter activity;GO:0005298//proline:sodium symporter activity,-
55118,0,0,0,0,0,13,0,0,3,0,5,0,CRTAC1;cartilage acidic protein 1,GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome,-,GO:0005509//calcium ion binding,K08023//TGF-beta signaling pathway
55119,105,0,0,0,42,28,17,0,16,0,0,0,PRPF38B;pre-mRNA processing factor 38B,GO:0005681//spliceosomal complex,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding,K12850//Spliceosome
55120,0,34,0,65,85,16,0,0,45,0,0,0,"FANCL;Fanconi anemia, complementation group L",GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043240//Fanconi anaemia nuclear complex,GO:0006974//cellular response to DNA damage stimulus;GO:0007276//gamete generation;GO:0042127//regulation of cell proliferation;GO:0006513//protein monoubiquitination;GO:0006281//DNA repair,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0031625//ubiquitin protein ligase binding,K10606//Fanconi anemia pathway;Ubiquitin mediated proteolysis
55122,1,0,0,0,11,6,10,9,16,0,0,0,AKIRIN2;akirin 2,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009790//embryo development;GO:0008284//positive regulation of cell proliferation;GO:0032755//positive regulation of interleukin-6 production;GO:0045087//innate immune response;GO:0010950//positive regulation of endopeptidase activity;GO:0006351//transcription, DNA-templated;GO:0032496//response to lipopolysaccharide;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0019899//enzyme binding,-
55124,1,0,0,0,0,0,38,0,71,0,6,0,PIWIL2;piwi-like RNA-mediated gene silencing 2,GO:0033391//chromatoid body;GO:0005844//polysome;GO:0043186//P granule;GO:0071546//pi-body;GO:0005737//cytoplasm,GO:0031047//gene silencing by RNA;GO:0045727//positive regulation of translation;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0060903//positive regulation of meiosis I;GO:0000966//RNA 5'-end processing;GO:0030718//germ-line stem cell maintenance;GO:0007126//meiotic nuclear division;GO:0007275//multicellular organismal development;GO:0048477//oogenesis;GO:0007283//spermatogenesis,GO:0003729//mRNA binding;GO:0034584//piRNA binding,K02156//Dorso-ventral axis formation
55125,162,0,0,49,55,10,0,0,39,0,5,119,CEP192;centrosomal protein 192kDa,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051225//spindle assembly;GO:0010923//negative regulation of phosphatase activity;GO:0051298//centrosome duplication,GO:0005515//protein binding;GO:0019902//phosphatase binding,K14299//RNA transport
55127,15,349,118,696,900,30,82,0,101,1,402,5,HEATR1;HEAT repeat containing 1,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005634//nucleus,GO:0006364//rRNA processing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14550//Ribosome biogenesis in eukaryotes
55128,0,0,0,35,42,17,0,0,19,0,18,0,TRIM68;tripartite motif containing 68,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,GO:0051865//protein autoubiquitination;GO:0060765//regulation of androgen receptor signaling pathway,GO:0035035//histone acetyltransferase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0050681//androgen receptor binding;GO:0008270//zinc ion binding,-
55129,1,0,0,0,5,0,0,18,7,0,0,0,ANO10;anoctamin 10,GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008219//cell death;GO:1902476//chloride transmembrane transport;GO:0006812//cation transport;GO:0034220//ion transmembrane transport;GO:0006821//chloride transport;GO:0055085//transmembrane transport,GO:0005227//calcium activated cation channel activity;GO:0005229//intracellular calcium activated chloride channel activity,-
55130,0,0,0,0,4,4,13,0,25,0,0,0,ARMC4;armadillo repeat containing 4,GO:0005930//axoneme;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0097546//ciliary base,GO:0036158//outer dynein arm assembly;GO:0070986//left/right axis specification;GO:0030030//cell projection organization;GO:0021591//ventricular system development;GO:0003341//cilium movement,-,K02105//Leukocyte transendothelial migration;Tight junction;Bacterial invasion of epithelial cells;HTLV-I infection;Pathogenic Escherichia coli infection;Thyroid cancer;Melanogenesis;Focal adhesion;Endometrial cancer;Prostate cancer;Basal cell carcinoma;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Adherens junction;Colorectal cancer;Wnt signaling pathway;K10056//Acute myeloid leukemia;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Transcriptional misregulation in cancer
55131,76,0,0,8,8,0,0,63,32,0,4,0,RBM28;RNA binding motif protein 28,GO:0005681//spliceosomal complex;GO:0005730//nucleolus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K14573//Ribosome biogenesis in eukaryotes
55132,0,48,0,8,65,24,33,0,5,0,0,0,"LARP1B;La ribonucleoprotein domain family, member 1B",GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,K11090//Systemic lupus erythematosus
55133,0,24,0,9,36,4,15,0,31,0,9,0,SRBD1;S1 RNA binding domain 1,-,GO:0006139//nucleobase-containing compound metabolic process,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0003723//RNA binding",-
55135,8,68,24,95,111,0,27,1,3,0,154,2,"WRAP53;WD repeat containing, antisense to TP53",GO:0005730//nucleolus;GO:0005697//telomerase holoenzyme complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015030//Cajal body,GO:0032203//telomere formation via telomerase;GO:0051973//positive regulation of telomerase activity,GO:0005515//protein binding;GO:0003723//RNA binding,K03130//Basal transcription factors;Herpes simplex infection
55137,0,0,0,1,0,7,51,18,0,86,2,0,FIGN;fidgetin,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0016363//nuclear matrix;GO:0005815//microtubule organizing center,GO:0007067//mitotic nuclear division,GO:0008022//protein C-terminus binding;GO:0005524//ATP binding,-
55138,0,0,0,0,0,0,25,0,59,0,11,0,"FAM90A1;family with sequence similarity 90, member A1",-,-,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,-
55139,0,0,1,17,0,0,0,0,20,0,15,0,ANKZF1;ankyrin repeat and zinc finger domain containing 1,GO:0016020//membrane,-,GO:0046872//metal ion binding;GO:0005515//protein binding,-
55140,0,31,2,6,30,0,31,0,63,0,10,0,ELP3;elongator acetyltransferase complex subunit 3,"GO:0033588//Elongator holoenzyme complex;GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex;GO:0005737//cytoplasm;GO:0016591//DNA-directed RNA polymerase II, holoenzyme",GO:0016573//histone acetylation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0030335//positive regulation of cell migration;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045859//regulation of protein kinase activity;GO:0006325//chromatin organization,GO:0008607//phosphorylase kinase regulator activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0051536//iron-sulfur cluster binding,-
55142,0,0,0,5,17,0,0,118,26,0,0,0,"HAUS2;HAUS augmin-like complex, subunit 2",GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0070652//HAUS complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005874//microtubule,GO:0051225//spindle assembly;GO:0051297//centrosome organization;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,-,K11447//Transcriptional misregulation in cancer
55143,0,0,0,0,10,49,0,78,32,0,0,0,CDCA8;cell division cycle associated 8,"GO:0030496//midbody;GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0005829//cytosol;GO:0005634//nucleus;GO:0032133//chromosome passenger complex;GO:0000775//chromosome, centromeric region;GO:0010369//chromocenter;GO:0043234//protein complex;GO:0005819//spindle",GO:0000278//mitotic cell cycle;GO:0051276//chromosome organization;GO:0007080//mitotic metaphase plate congression,GO:0005515//protein binding,-
55144,0,0,0,0,0,0,10,1,29,0,0,398,"LRRC8D;leucine rich repeat containing 8 family, member D",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006811//ion transport,GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway
55145,0,0,0,0,21,0,0,0,9,0,0,0,"THAP1;THAP domain containing, apoptosis associated protein 1",GO:0016605//PML body;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0007346//regulation of mitotic cell cycle;GO:0001935//endothelial cell proliferation;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,K00943//Two-component system;One carbon pool by folate;Metabolic pathways;Pyrimidine metabolism
55146,45,23,2,0,32,0,0,0,0,0,0,0,"ZDHHC4;zinc finger, DHHC-type containing 4",GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0008152//metabolic process,GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
55147,1,0,0,19,32,0,21,0,23,1,0,414,RBM23;RNA binding motif protein 23,GO:0016020//membrane;GO:0005634//nucleus,GO:0006397//mRNA processing,GO:0003723//RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
55148,0,0,1,0,63,21,0,62,15,0,0,0,UBR7;ubiquitin protein ligase E3 component n-recognin 7 (putative),-,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
55149,0,0,0,0,54,0,0,0,39,0,15,0,MTPAP;mitochondrial poly(A) polymerase,GO:0005739//mitochondrion;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006378//mRNA polyadenylation;GO:0071044//histone mRNA catabolic process;GO:0008219//cell death;GO:0006351//transcription, DNA-templated",GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity;GO:0004652//polynucleotide adenylyltransferase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0002134//UTP binding;GO:0030145//manganese ion binding;GO:0042802//identical protein binding,K11447//Transcriptional misregulation in cancer
5515,0,14,3,24,137,0,0,0,2,0,16,0,"PPP2CA;protein phosphatase 2, catalytic subunit, alpha isozyme","GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0000922//spindle pole;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0000159//protein phosphatase type 2A complex;GO:0000775//chromosome, centromeric region;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome","GO:0006355//regulation of transcription, DNA-templated;GO:0006672//ceramide metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0070208//protein heterotrimerization;GO:0010469//regulation of receptor activity;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0042518//negative regulation of tyrosine phosphorylation of Stat3 protein;GO:0030111//regulation of Wnt signaling pathway;GO:0010033//response to organic substance;GO:0030308//negative regulation of cell growth;GO:0007498//mesoderm development;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0031952//regulation of protein autophosphorylation;GO:0007126//meiotic nuclear division;GO:0040008//regulation of growth;GO:0016070//RNA metabolic process;GO:0006275//regulation of DNA replication;GO:0016071//mRNA metabolic process;GO:0000278//mitotic cell cycle;GO:0045595//regulation of cell differentiation;GO:0007084//mitotic nuclear envelope reassembly;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030155//regulation of cell adhesion;GO:0000188//inactivation of MAPK activity;GO:0006915//apoptotic process;GO:0019932//second-messenger-mediated signaling;GO:0042176//regulation of protein catabolic process;GO:0006470//protein dephosphorylation",GO:0008022//protein C-terminus binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0046983//protein dimerization activity;GO:0050811//GABA receptor binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K04382//mRNA surveillance pathway;Cell cycle - yeast;Oocyte meiosis;Wnt signaling pathway;Hepatitis C;TGF-beta signaling pathway;Meiosis - yeast;Long-term depression;Chagas disease (American trypanosomiasis);Dopaminergic synapse;Tight junction
55150,0,33,85,31,66,0,25,0,0,0,52,0,C19orf73;chromosome 19 open reading frame 73,-,-,-,-
55151,0,1,0,0,1,0,0,0,29,123,0,0,TMEM38B;transmembrane protein 38B,GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0033017//sarcoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0071805//potassium ion transmembrane transport,GO:0005267//potassium channel activity,-
55152,0,340,190,347,811,22,0,280,50,252,522,0,DALRD3;DALR anticodon binding domain containing 3,-,GO:0006420//arginyl-tRNA aminoacylation,GO:0005524//ATP binding;GO:0004814//arginine-tRNA ligase activity,-
55153,0,0,0,23,23,35,48,0,20,0,0,0,SDAD1;SDA1 domain containing 1,GO:0005730//nucleolus,GO:0015031//protein transport;GO:0000055//ribosomal large subunit export from nucleus;GO:0030036//actin cytoskeleton organization;GO:0042273//ribosomal large subunit biogenesis,-,-
55154,0,0,0,7,0,0,0,0,0,0,0,0,"MSTO1;misato 1, mitochondrial distribution and morphology regulator",GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm,GO:0007005//mitochondrion organization;GO:0048311//mitochondrion distribution,-,-
55156,9,1,0,9,69,38,36,32,14,0,0,0,ARMC1;armadillo repeat containing 1,GO:0005739//mitochondrion,GO:0030001//metal ion transport,GO:0046872//metal ion binding,-
55157,115,106,2,31,70,0,31,0,13,0,46,0,"DARS2;aspartyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0010467//gene expression;GO:0070145//mitochondrial asparaginyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004815//aspartate-tRNA ligase activity;GO:0000049//tRNA binding;GO:0005524//ATP binding;GO:0050560//aspartate-tRNA(Asn) ligase activity,K01876//Aminoacyl-tRNA biosynthesis
55159,0,1,0,11,0,19,23,0,39,0,13,0,RFWD3;ring finger and WD repeat domain 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016605//PML body;GO:0035861//site of double-strand break,GO:0031571//mitotic G1 DNA damage checkpoint;GO:2000001//regulation of DNA damage checkpoint;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0097371//MDM2/MDM4 family protein binding,-
5516,17,3,0,39,63,9,0,0,21,0,0,0,"PPP2CB;protein phosphatase 2, catalytic subunit, beta isozyme","GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0000922//spindle pole;GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region",GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0046580//negative regulation of Ras protein signal transduction;GO:0046677//response to antibiotic;GO:0008637//apoptotic mitochondrial changes;GO:0034976//response to endoplasmic reticulum stress;GO:0042542//response to hydrogen peroxide;GO:0006470//protein dephosphorylation;GO:0010468//regulation of gene expression,GO:0004722//protein serine/threonine phosphatase activity;GO:0008022//protein C-terminus binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K04382//TGF-beta signaling pathway;Tight junction;Dopaminergic synapse;Chagas disease (American trypanosomiasis);Long-term depression;Meiosis - yeast;Cell cycle - yeast;mRNA surveillance pathway;Hepatitis C;Wnt signaling pathway;Oocyte meiosis
55160,51,0,0,5,0,1,32,44,61,30,36,1,ARHGEF10L;Rho guanine nucleotide exchange factor (GEF) 10-like,GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K04436//MAPK signaling pathway;K05156//Cytokine-cytokine receptor interaction
55161,0,0,0,0,19,15,0,0,51,93,20,160,TMEM33;transmembrane protein 33,GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
55163,0,1,2,6,13,0,0,49,32,0,0,436,PNPO;pyridoxamine 5'-phosphate oxidase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0042823//pyridoxal phosphate biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006766//vitamin metabolic process;GO:0008615//pyridoxine biosynthetic process;GO:0042816//vitamin B6 metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0010181//FMN binding;GO:0004733//pyridoxamine-phosphate oxidase activity,K00275//Metabolic pathways;Vitamin B6 metabolism
55164,106,0,0,9,8,7,0,0,52,0,5,1,"SHQ1;SHQ1, H/ACA ribonucleoprotein assembly factor",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0022618//ribonucleoprotein complex assembly;GO:0043065//positive regulation of apoptotic process;GO:2000233//negative regulation of rRNA processing,GO:0005515//protein binding,-
55165,0,0,0,0,0,50,0,0,15,0,0,0,CEP55;centrosomal protein 55kDa,GO:0045171//intercellular bridge;GO:0030496//midbody;GO:0016020//membrane;GO:0032154//cleavage furrow;GO:0005814//centriole;GO:0005813//centrosome,GO:0045184//establishment of protein localization;GO:0000281//mitotic cytokinesis;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,K12478//Phagosome;Endocytosis;Tuberculosis;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
55166,0,0,0,0,17,11,11,0,0,0,0,0,CENPQ;centromere protein Q,"GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus;GO:0005829//cytosol",GO:0006334//nucleosome assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0000278//mitotic cell cycle,-,-
55167,0,0,1,14,32,17,17,0,36,0,10,0,MSL2;male-specific lethal 2 homolog (Drosophila),GO:0005654//nucleoplasm;GO:0072487//MSL complex,GO:0043984//histone H4-K16 acetylation;GO:0006325//chromatin organization,GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
55168,0,0,0,0,32,21,0,0,0,0,7,430,MRPS18A;mitochondrial ribosomal protein S18A,GO:0005763//mitochondrial small ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
55170,0,1,0,62,95,49,0,153,5,0,67,0,PRMT6;protein arginine methyltransferase 6,GO:0005634//nucleus;GO:0005829//cytosol,"GO:0043985//histone H4-R3 methylation;GO:0006351//transcription, DNA-templated;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034970//histone H3-R2 methylation;GO:0016032//viral process;GO:0016571//histone methylation;GO:0006284//base-excision repair",GO:0005515//protein binding;GO:0042393//histone binding;GO:0070612//histone methyltransferase activity (H2A-R3 specific);GO:0042054//histone methyltransferase activity;GO:0070611//histone methyltransferase activity (H3-R2 specific);GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0044020//histone methyltransferase activity (H4-R3 specific),-
55171,0,0,1,10,9,23,5,27,46,0,0,0,TBCCD1;TBCC domain containing 1,GO:0031616//spindle pole centrosome;GO:0005737//cytoplasm,GO:0000902//cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0030334//regulation of cell migration;GO:0051684//maintenance of Golgi location;GO:0051661//maintenance of centrosome location;GO:0008360//regulation of cell shape,GO:0003779//actin binding,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
55172,116,22,0,0,1,16,0,0,28,0,0,0,"DNAAF2;dynein, axonemal, assembly factor 2",GO:0005737//cytoplasm,GO:0032526//response to retinoic acid;GO:0071973//bacterial-type flagellum-dependent cell motility;GO:0070286//axonemal dynein complex assembly;GO:0060285//cilium-dependent cell motility,GO:0005515//protein binding,-
55173,0,27,1,12,17,0,0,0,46,0,0,0,MRPS10;mitochondrial ribosomal protein S10,GO:0005739//mitochondrion;GO:0005840//ribosome,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
55174,0,23,1,96,29,15,0,0,12,0,17,0,INTS10;integrator complex subunit 10,GO:0032039//integrator complex,GO:0016180//snRNA processing,GO:0005515//protein binding,-
55175,90,35,0,8,50,0,20,41,34,0,6,0,KLHL11;kelch-like family member 11,-,-,-,-
55176,87,112,212,551,560,0,4,1,152,0,585,1,SEC61A2;Sec61 alpha 2 subunit (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0015031//protein transport;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I",GO:0043022//ribosome binding,K10956//Protein export;Vibrio cholerae infection;Protein processing in endoplasmic reticulum;Phagosome
55177,0,0,0,0,7,0,18,27,16,0,0,0,RMDN3;regulator of microtubule dynamics 3,GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005874//microtubule;GO:0000922//spindle pole,GO:0006915//apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0030154//cell differentiation,GO:0005515//protein binding,-
55178,0,7,51,15,37,0,0,0,2,0,32,0,RNMTL1;RNA methyltransferase like 1,GO:0005739//mitochondrion,GO:0001510//RNA methylation;GO:0006396//RNA processing,GO:0008173//RNA methyltransferase activity;GO:0044822//poly(A) RNA binding,-
55179,0,33,0,14,35,21,0,54,38,0,3,0,FAIM;Fas apoptotic inhibitory molecule,GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors,-,K14209//Protein digestion and absorption;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
5518,0,3,0,10,31,0,58,0,33,0,7,0,"PPP2R1A;protein phosphatase 2, regulatory subunit A, alpha","GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0015630//microtubule cytoskeleton;GO:0000775//chromosome, centromeric region;GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus","GO:0070262//peptidyl-serine dephosphorylation;GO:0040008//regulation of growth;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0030308//negative regulation of cell growth;GO:0010033//response to organic substance;GO:0042518//negative regulation of tyrosine phosphorylation of Stat3 protein;GO:0030111//regulation of Wnt signaling pathway;GO:0006461//protein complex assembly;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006672//ceramide metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0006915//apoptotic process;GO:0019932//second-messenger-mediated signaling;GO:0006470//protein dephosphorylation;GO:0030155//regulation of cell adhesion;GO:0000188//inactivation of MAPK activity;GO:0007084//mitotic nuclear envelope reassembly;GO:0007059//chromosome segregation;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045595//regulation of cell differentiation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006275//regulation of DNA replication",GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0008601//protein phosphatase type 2A regulator activity;GO:0003823//antigen binding,K03456//Cell cycle - yeast;mRNA surveillance pathway;Hepatitis C;Wnt signaling pathway;Oocyte meiosis;TGF-beta signaling pathway;Dopaminergic synapse;Tight junction;Chagas disease (American trypanosomiasis);Meiosis - yeast;Long-term depression
55180,0,40,0,0,13,10,2,152,25,0,20,0,LINS;lines homolog (Drosophila),-,-,-,-
55181,0,0,0,0,9,17,1,0,40,0,10,0,SMG8;SMG8 nonsense mediated mRNA decay factor,GO:0005829//cytosol,"GO:0016071//mRNA metabolic process;GO:0045859//regulation of protein kinase activity;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0010467//gene expression",GO:0005515//protein binding,-
55182,0,34,0,43,17,0,0,0,13,0,47,0,RNF220;ring finger protein 220,GO:0005737//cytoplasm,GO:0051865//protein autoubiquitination;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
55183,64,32,0,54,52,45,0,60,14,1,0,286,RIF1;replication timing regulatory factor 1,"GO:0005886//plasma membrane;GO:0005819//spindle;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0001939//female pronucleus;GO:0005730//nucleolus;GO:0001940//male pronucleus;GO:0005634//nucleus",GO:0019827//stem cell maintenance;GO:0007049//cell cycle;GO:0006974//cellular response to DNA damage stimulus,-,K11138//Galactose metabolism
55184,0,0,0,0,0,0,19,0,30,0,6,0,DZANK1;double zinc ribbon and ankyrin repeat domains 1,-,-,GO:0008270//zinc ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
55186,0,1,0,41,35,29,70,0,30,0,13,0,"SLC25A36;solute carrier family 25 (pyrimidine nucleotide carrier ), member 36",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0032355//response to estradiol;GO:0055085//transmembrane transport,-,-
55187,8,131,3,49,177,84,60,0,125,242,16,0,VPS13D;vacuolar protein sorting 13 homolog D (S. cerevisiae),GO:0070062//extracellular vesicular exosome,-,-,-
55188,0,0,0,1,48,0,0,12,18,166,6,0,RIC8B;RIC8 guanine nucleotide exchange factor B,GO:0005813//centrosome;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0001965//G-protein alpha-subunit binding;GO:0005085//guanyl-nucleotide exchange factor activity,-
5519,0,124,78,144,80,0,51,0,12,0,94,318,"PPP2R1B;protein phosphatase 2, regulatory subunit A, beta",GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome,GO:0060561//apoptotic process involved in morphogenesis;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005515//protein binding,K03456//mRNA surveillance pathway;Cell cycle - yeast;Oocyte meiosis;Hepatitis C;Wnt signaling pathway;TGF-beta signaling pathway;Chagas disease (American trypanosomiasis);Dopaminergic synapse;Tight junction;Long-term depression;Meiosis - yeast
55190,0,0,0,11,18,0,0,0,0,0,4,16,NUDT11;nudix (nucleoside diphosphate linked moiety X)-type motif 11,GO:0005829//cytosol;GO:0005622//intracellular,GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process,"GO:0052844//inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity;GO:0052843//inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity;GO:0052847//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052840//inositol diphosphate tetrakisphosphate diphosphatase activity;GO:0008486//diphosphoinositol-polyphosphate diphosphatase activity;GO:0046872//metal ion binding;GO:0052848//inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity;GO:0052846//inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity;GO:0052845//inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity",-
55191,0,1,0,0,21,7,56,0,39,0,4,0,NADSYN1;NAD synthetase 1,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006766//vitamin metabolic process;GO:0009435//NAD biosynthetic process;GO:0019674//NAD metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,"GO:0005524//ATP binding;GO:0016810//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;GO:0003952//NAD+ synthase (glutamine-hydrolyzing) activity",K01950//Metabolic pathways;Nicotinate and nicotinamide metabolism
55192,0,0,0,18,1,31,0,234,59,0,49,280,"DNAJC17;DnaJ (Hsp40) homolog, subfamily C, member 17",-,GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
55193,0,2,0,67,176,24,53,0,38,0,20,0,PBRM1;polybromo 1,GO:0000776//kinetochore;GO:0000228//nuclear chromosome,"GO:0001890//placenta development;GO:0008285//negative regulation of cell proliferation;GO:0007067//mitotic nuclear division;GO:0007507//heart development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0005515//protein binding,-
55194,0,41,0,0,17,0,0,182,15,0,39,0,EVA1B;eva-1 homolog B (C. elegans),GO:0016021//integral component of membrane,-,-,-
55195,133,0,0,0,0,0,0,0,28,0,0,0,C14orf105;chromosome 14 open reading frame 105,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
55196,0,0,0,16,19,0,0,0,55,0,8,0,KIAA1551;KIAA1551,-,-,-,-
55197,0,68,1,78,143,0,32,0,41,0,0,0,RPRD1A;regulation of nuclear pre-mRNA domain containing 1A,"GO:0016591//DNA-directed RNA polymerase II, holoenzyme",GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain,-,-
55198,0,0,0,52,107,42,17,54,21,1,0,516,"APPL2;adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2",GO:0016581//NuRD complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0031901//early endosome membrane;GO:0010008//endosome membrane,GO:0007049//cell cycle;GO:0007165//signal transduction;GO:0008283//cell proliferation,GO:0005515//protein binding,K08733//Colorectal cancer;Pathways in cancer
55199,1,0,0,0,15,0,0,0,13,120,46,0,"FAM86C1;family with sequence similarity 86, member C1",-,-,-,K03842//N-Glycan biosynthesis;Various types of N-glycan biosynthesis;Metabolic pathways
552,0,0,0,12,0,0,0,0,39,0,0,0,AVPR1A;arginine vasopressin receptor 1A,GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0031410//cytoplasmic vesicle,GO:0045907//positive regulation of vasoconstriction;GO:0007621//negative regulation of female receptivity;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0035176//social behavior;GO:0002125//maternal aggressive behavior;GO:0051412//response to corticosterone;GO:0043084//penile erection;GO:0051970//negative regulation of transmission of nerve impulse;GO:0001992//regulation of systemic arterial blood pressure by vasopressin;GO:0014902//myotube differentiation;GO:0021537//telencephalon development;GO:0008015//blood circulation;GO:0007625//grooming behavior;GO:0042631//cellular response to water deprivation;GO:0019722//calcium-mediated signaling;GO:0007202//activation of phospholipase C activity;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0042713//sperm ejaculation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030307//positive regulation of cell growth;GO:0006091//generation of precursor metabolites and energy;GO:0035815//positive regulation of renal sodium excretion;GO:0014049//positive regulation of glutamate secretion;GO:0008284//positive regulation of cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0032849//positive regulation of cellular pH reduction;GO:0010460//positive regulation of heart rate;GO:0042711//maternal behavior,GO:0005515//protein binding;GO:0005000//vasopressin receptor activity;GO:0005080//protein kinase C binding;GO:0017046//peptide hormone binding;GO:0031894//V1A vasopressin receptor binding,K04226//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction
5520,0,20,0,5,78,0,0,0,17,0,0,0,"PPP2R2A;protein phosphatase 2, regulatory subunit B, alpha",GO:0005654//nucleoplasm;GO:0000159//protein phosphatase type 2A complex;GO:0005829//cytosol,"GO:0043278//response to morphine;GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006470//protein dephosphorylation;GO:0010467//gene expression;GO:0007084//mitotic nuclear envelope reassembly;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle",GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,K04354//Hepatitis C;Dopaminergic synapse;Tight junction;Chagas disease (American trypanosomiasis);mRNA surveillance pathway;Cell cycle - yeast
55200,0,0,0,0,0,49,55,0,35,0,10,0,"PLEKHG6;pleckstrin homology domain containing, family G (with RhoGef domain) member 6",GO:0032154//cleavage furrow;GO:0000922//spindle pole;GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity,GO:0005096//GTPase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K12330//Regulation of actin cytoskeleton;Vascular smooth muscle contraction
55201,76,0,0,0,0,0,50,91,48,0,0,0,MAP1S;microtubule-associated protein 1S,GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005819//spindle;GO:0045202//synapse;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0007399//nervous system development;GO:0006309//apoptotic DNA fragmentation;GO:0047497//mitochondrion transport along microtubule;GO:0007420//brain development;GO:0048812//neuron projection morphogenesis;GO:0001578//microtubule bundle formation;GO:0097194//execution phase of apoptosis,GO:0051015//actin filament binding;GO:0004536//deoxyribonuclease activity;GO:0003677//DNA binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0015631//tubulin binding;GO:0048487//beta-tubulin binding;GO:0005515//protein binding,-
55203,0,0,0,3,0,34,0,38,24,0,0,0,"LGI2;leucine-rich repeat LGI family, member 2",GO:0005576//extracellular region,-,-,K06839//Axon guidance
55204,0,0,1,27,89,27,0,69,22,0,3,0,GOLPH3L;golgi phosphoprotein 3-like,GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0032588//trans-Golgi network membrane,GO:0050714//positive regulation of protein secretion;GO:0007030//Golgi organization,GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0005515//protein binding,K15620//Transcriptional misregulation in cancer
55205,69,75,3,75,444,11,0,2,27,0,26,0,ZNF532;zinc finger protein 532,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
55206,0,1,1,33,147,23,4,0,118,0,36,0,SBNO1;strawberry notch homolog 1 (Drosophila),-,"GO:0006355//regulation of transcription, DNA-templated",-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
55207,0,10,1,21,51,0,0,0,0,0,0,0,ARL8B;ADP-ribosylation factor-like 8B,GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005737//cytoplasm;GO:0051233//spindle midzone;GO:0016020//membrane;GO:0030496//midbody;GO:0070062//extracellular vesicular exosome,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0051301//cell division;GO:0007059//chromosome segregation;GO:0007049//cell cycle,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0043014//alpha-tubulin binding;GO:0019003//GDP binding;GO:0048487//beta-tubulin binding,-
55208,0,0,0,0,0,0,0,0,58,30,2,0,"DCUN1D2;DCN1, defective in cullin neddylation 1, domain containing 2",-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
55209,5,0,1,28,136,23,34,4,58,0,0,0,SETD5;SET domain containing 5,-,-,-,K09189//Lysine degradation
5521,0,0,0,0,0,8,0,0,30,0,0,0,"PPP2R2B;protein phosphatase 2, regulatory subunit B, beta",GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane;GO:0000159//protein phosphatase type 2A complex;GO:0005856//cytoskeleton,GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,K04354//Hepatitis C;Chagas disease (American trypanosomiasis);Dopaminergic synapse;Tight junction;mRNA surveillance pathway;Cell cycle - yeast
55210,0,0,0,0,0,19,0,56,3,0,35,0,"ATAD3A;ATPase family, AAA domain containing 3A",GO:0042645//mitochondrial nucleoid;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0043066//negative regulation of apoptotic process;GO:0016049//cell growth,GO:0005524//ATP binding,K12196//Endocytosis;K03064//Proteasome;Epstein-Barr virus infection
55211,0,0,0,0,0,39,39,0,5,0,0,0,DPPA4;developmental pluripotency associated 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0060484//lung-associated mesenchyme development",GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
55212,9,0,0,0,39,6,0,94,54,0,0,0,BBS7;Bardet-Biedl syndrome 7,GO:0060170//ciliary membrane;GO:0005930//axoneme;GO:0005813//centrosome;GO:0005634//nucleus;GO:0036064//ciliary basal body;GO:0034464//BBSome,GO:0032402//melanosome transport;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007368//determination of left/right symmetry;GO:0035058//nonmotile primary cilium assembly;GO:0007601//visual perception;GO:0007224//smoothened signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0045444//fat cell differentiation;GO:0051877//pigment granule aggregation in cell center;GO:0007420//brain development;GO:0060021//palate development;GO:0015031//protein transport;GO:0001947//heart looping;GO:0001654//eye development;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0060271//cilium morphogenesis;GO:0060173//limb development,GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0005515//protein binding,-
55213,76,0,0,12,82,12,23,43,0,0,0,0,RCBTB1;regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated",-,-
55214,70,33,1,23,39,37,2,63,32,0,27,0,LEPREL1;leprecan-like 1,GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005604//basement membrane;GO:0005794//Golgi apparatus,GO:0030198//extracellular matrix organization;GO:0055114//oxidation-reduction process;GO:0008285//negative regulation of cell proliferation;GO:0019511//peptidyl-proline hydroxylation;GO:0032963//collagen metabolic process,GO:0031418//L-ascorbic acid binding;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0005506//iron ion binding,-
55215,0,67,2,99,23,0,23,0,49,0,123,0,"FANCI;Fanconi anemia, complementation group I",GO:0016020//membrane;GO:0005654//nucleoplasm,GO:0007049//cell cycle;GO:0031398//positive regulation of protein ubiquitination;GO:0006281//DNA repair,GO:0005515//protein binding;GO:0070182//DNA polymerase binding;GO:0003677//DNA binding,K10895//Fanconi anemia pathway
55216,0,0,0,0,13,0,0,0,4,0,0,0,C11orf57;chromosome 11 open reading frame 57,-,-,-,-
55217,0,0,0,3,0,0,0,0,0,0,0,0,"TMLHE;trimethyllysine hydroxylase, epsilon",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0045329//carnitine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0051354//negative regulation of oxidoreductase activity;GO:0044281//small molecule metabolic process,"GO:0050353//trimethyllysine dioxygenase activity;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding",K00474//Lysine degradation
55218,10,0,0,0,41,8,27,0,77,0,0,0,EXD2;exonuclease 3'-5' domain containing 2,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0008408//3'-5' exonuclease activity;GO:0003676//nucleic acid binding,-
55219,0,0,0,17,0,0,0,90,0,0,4,2,TMEM57;transmembrane protein 57,GO:0031965//nuclear membrane;GO:0044306//neuron projection terminus;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0045202//synapse;GO:0030424//axon,GO:0007420//brain development,-,K14000//Protein processing in endoplasmic reticulum;K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12478//Tuberculosis;Endocytosis;Phagosome
5522,47,0,0,1,20,0,0,169,37,0,15,0,"PPP2R2C;protein phosphatase 2, regulatory subunit B, gamma",GO:0000159//protein phosphatase type 2A complex,GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity,GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,K04354//Hepatitis C;Tight junction;Dopaminergic synapse;Chagas disease (American trypanosomiasis);mRNA surveillance pathway;Cell cycle - yeast
55220,0,0,0,0,0,0,17,0,12,0,32,0,KLHDC8A;kelch domain containing 8A,-,-,-,-
55222,0,0,0,0,1,64,65,55,14,144,0,0,LRRC20;leucine rich repeat containing 20,-,-,-,K10130//NF-kappa B signaling pathway;p53 signaling pathway;K12603//RNA degradation
55223,0,0,0,0,0,2,24,0,26,0,0,0,TRIM62;tripartite motif containing 62,GO:0005737//cytoplasm,GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:1902186//regulation of viral release from host cell;GO:0046596//regulation of viral entry into host cell;GO:0032897//negative regulation of viral transcription;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
55225,75,52,0,8,44,30,0,0,0,1,9,0,"RAVER2;ribonucleoprotein, PTB-binding 2",GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K11219//Jak-STAT signaling pathway;Influenza A;Herpes simplex infection;Osteoclast differentiation;Toxoplasmosis;Hepatitis C;Measles;Epstein-Barr virus infection
55226,108,0,0,8,22,28,33,70,28,12,2,0,NAT10;N-acetyltransferase 10 (GCN5-related),GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,GO:0008152//metabolic process,GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0008080//N-acetyltransferase activity,K14521//Ribosome biogenesis in eukaryotes
55227,0,27,0,12,24,33,43,0,32,0,0,0,LRRC1;leucine rich repeat containing 1,GO:0005737//cytoplasm;GO:0016020//membrane,-,-,K12796//NOD-like receptor signaling pathway
55228,0,0,0,0,1,0,18,57,44,0,0,0,PNMAL1;paraneoplastic Ma antigen family-like 1,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome
55229,0,0,0,3,0,12,0,31,26,153,0,0,PANK4;pantothenate kinase 4,GO:0005737//cytoplasm,GO:0015937//coenzyme A biosynthetic process;GO:0016310//phosphorylation,GO:0004594//pantothenate kinase activity;GO:0005524//ATP binding,K09680//Metabolic pathways;Pantothenate and CoA biosynthesis
5523,0,32,0,12,57,0,0,9,75,130,44,0,"PPP2R3A;protein phosphatase 2, regulatory subunit B'', alpha",GO:0000159//protein phosphatase type 2A complex,GO:0006470//protein dephosphorylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0001754//eye photoreceptor cell differentiation;GO:0061053//somite development;GO:0090249//regulation of cell motility involved in somitogenic axis elongation;GO:0007525//somatic muscle development;GO:0045732//positive regulation of protein catabolic process;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0050790//regulation of catalytic activity,GO:0005509//calcium ion binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0005515//protein binding,K11583//mRNA surveillance pathway;Dopaminergic synapse
55230,179,0,0,0,48,25,5,0,55,0,0,0,USP40;ubiquitin specific peptidase 40,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
55231,0,0,0,0,0,0,0,0,25,0,0,0,CCDC87;coiled-coil domain containing 87,-,GO:0000226//microtubule cytoskeleton organization;GO:0000910//cytokinesis,GO:0008017//microtubule binding,-
55233,0,18,0,65,63,0,0,0,10,0,0,0,MOB1A;MOB kinase activator 1A,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0035329//hippo signaling,GO:0046872//metal ion binding;GO:0005515//protein binding,K06685//Cell cycle - yeast
55234,94,0,1,57,106,40,30,0,10,0,5,487,SMU1;smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans),GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,-
55236,66,22,0,41,146,0,59,0,23,0,0,0,UBA6;ubiquitin-like modifier activating enzyme 6,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0019780//FAT10 activating enzyme activity,K10699//Ubiquitin mediated proteolysis
55237,0,0,0,0,0,0,0,0,16,0,0,0,VRTN;vertebrae development associated,-,"GO:0006313//transposition, DNA-mediated",GO:0004803//transposase activity;GO:0043565//sequence-specific DNA binding,-
55238,0,7,1,0,0,0,24,0,1,0,12,0,"SLC38A7;solute carrier family 38, member 7",GO:0030424//axon;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body,GO:0015825//L-serine transport;GO:0006868//glutamine transport;GO:0015810//aspartate transport;GO:0006867//asparagine transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0015817//histidine transport;GO:0015821//methionine transport;GO:0015813//L-glutamate transport;GO:0015808//L-alanine transport;GO:0015803//branched-chain amino acid transport;GO:0006814//sodium ion transport,GO:0015186//L-glutamine transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0005290//L-histidine transmembrane transporter activity;GO:0015182//L-asparagine transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0015190//L-leucine transmembrane transporter activity;GO:0015191//L-methionine transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity,-
55239,0,18,0,34,81,12,0,0,31,0,37,0,OGFOD1;2-oxoglutarate and iron-dependent oxygenase domain containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule,GO:0019511//peptidyl-proline hydroxylation;GO:0034063//stress granule assembly;GO:0055114//oxidation-reduction process;GO:0006449//regulation of translational termination;GO:0008283//cell proliferation,GO:0005506//iron ion binding;GO:0031544//peptidyl-proline 3-dioxygenase activity;GO:0031418//L-ascorbic acid binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
5524,0,65,0,9,32,33,0,0,58,0,0,0,"PPP2R4;protein phosphatase 2A activator, regulatory subunit 4",GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0000159//protein phosphatase type 2A complex;GO:0034704//calcium channel complex;GO:0005634//nucleus,GO:0043065//positive regulation of apoptotic process;GO:0035307//positive regulation of protein dephosphorylation;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0006457//protein folding;GO:0035308//negative regulation of protein dephosphorylation;GO:0006200//ATP catabolic process;GO:0000413//protein peptidyl-prolyl isomerization;GO:0030472//mitotic spindle organization in nucleus,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding;GO:0051721//protein phosphatase 2A binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0016887//ATPase activity;GO:0008160//protein tyrosine phosphatase activator activity;GO:0005524//ATP binding,-
55240,0,0,0,0,0,0,18,0,17,0,0,0,"STEAP3;STEAP family member 3, metalloreductase",GO:0005771//multivesicular body;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane,GO:0033572//transferrin transport;GO:0006879//cellular iron ion homeostasis;GO:0007049//cell cycle;GO:0015677//copper ion import;GO:0055114//oxidation-reduction process;GO:1902167//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0009306//protein secretion;GO:0055085//transmembrane transport;GO:1990182//exosomal secretion,GO:0000293//ferric-chelate reductase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K10142//p53 signaling pathway
55243,1,0,0,0,0,46,43,6,51,29,43,322,KIRREL;kin of IRRE like (Drosophila),GO:0005911//cell-cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0043198//dendritic shaft;GO:0016021//integral component of membrane,GO:0030838//positive regulation of actin filament polymerization;GO:0001933//negative regulation of protein phosphorylation;GO:0007588//excretion;GO:0016337//single organismal cell-cell adhesion,GO:0005515//protein binding;GO:0017022//myosin binding,K14319//RNA transport;K06527//NF-kappa B signaling pathway;HTLV-I infection;Cell adhesion molecules (CAMs);Malaria;Leukocyte transendothelial migration;African trypanosomiasis;K06754//Axon guidance;K06755//Axon guidance
55244,93,0,0,0,0,0,0,0,57,0,0,0,"SLC47A1;solute carrier family 47 (multidrug and toxin extrusion), member 1",GO:0016021//integral component of membrane;GO:0031988//membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0015695//organic cation transport;GO:0006855//drug transmembrane transport;GO:1902600//hydrogen ion transmembrane transport,GO:0015238//drug transmembrane transporter activity;GO:0005451//monovalent cation:proton antiporter activity,-
55245,92,0,0,5,45,14,0,26,0,0,0,0,UQCC1;ubiquinol-cytochrome c reductase complex assembly factor 1,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005739//mitochondrion,-,-,-
55246,0,21,1,13,87,1,0,0,51,0,0,0,CCDC25;coiled-coil domain containing 25,GO:0070062//extracellular vesicular exosome,-,-,-
55247,0,0,0,0,0,0,25,0,20,135,0,0,NEIL3;nei endonuclease VIII-like 3 (E. coli),GO:0005634//nucleus,"GO:0006284//base-excision repair;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006289//nucleotide-excision repair",GO:0019104//DNA N-glycosylase activity;GO:0000405//bubble DNA binding;GO:0003697//single-stranded DNA binding;GO:0008270//zinc ion binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding,K10569//Base excision repair
55248,0,0,0,0,1,22,0,0,16,0,0,0,TMEM206;transmembrane protein 206,GO:0016021//integral component of membrane;GO:0009986//cell surface,-,-,-
55249,0,47,0,37,111,0,48,17,93,0,24,0,YY1AP1;YY1 associated protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
5525,0,6,44,40,78,0,18,108,11,158,10,17,"PPP2R5A;protein phosphatase 2, regulatory subunit B', alpha","GO:0005634//nucleus;GO:0000159//protein phosphatase type 2A complex;GO:0031430//M band;GO:0000775//chromosome, centromeric region;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0016020//membrane",GO:0035307//positive regulation of protein dephosphorylation;GO:0090219//negative regulation of lipid kinase activity;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0019900//kinase binding,K11584//Wnt signaling pathway;Meiosis - yeast;Oocyte meiosis;Dopaminergic synapse;mRNA surveillance pathway
55250,0,1,0,11,65,0,0,0,49,0,6,0,ELP2;elongator acetyltransferase complex subunit 2,"GO:0005737//cytoplasm;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0033588//Elongator holoenzyme complex;GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex",GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0046425//regulation of JAK-STAT cascade,GO:0019901//protein kinase binding;GO:0003677//DNA binding,-
55251,100,16,0,39,164,0,13,0,4,0,14,0,PCMTD2;protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2,GO:0005737//cytoplasm,GO:0006479//protein methylation,GO:0004719//protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,-
55252,0,34,0,27,66,9,35,0,77,0,0,0,ASXL2;additional sex combs like transcriptional regulator 2,GO:0000790//nuclear chromatin,"GO:0006351//transcription, DNA-templated;GO:0045672//positive regulation of osteoclast differentiation;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048704//embryonic skeletal system morphogenesis;GO:1900159//positive regulation of bone mineralization involved in bone maturation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007512//adult heart development;GO:0045600//positive regulation of fat cell differentiation",GO:0042975//peroxisome proliferator activated receptor binding;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
55253,31,0,0,24,4,0,33,0,36,0,0,0,TYW1;tRNA-yW synthesizing protein 1 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0055114//oxidation-reduction process;GO:0008033//tRNA processing,"GO:0016829//lyase activity;GO:0016491//oxidoreductase activity;GO:0005506//iron ion binding;GO:0010181//FMN binding;GO:0051539//4 iron, 4 sulfur cluster binding",-
55254,0,0,0,0,0,24,0,0,42,0,6,0,TMEM39A;transmembrane protein 39A,GO:0016021//integral component of membrane,-,-,-
55255,0,25,1,18,80,0,0,0,0,0,0,0,WDR41;WD repeat domain 41,GO:0005765//lysosomal membrane,-,-,K10260//Ubiquitin mediated proteolysis
55256,0,63,2,163,271,0,23,0,49,0,4,0,ADI1;acireductone dioxygenase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0006595//polyamine metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0055114//oxidation-reduction process,GO:0005506//iron ion binding;GO:0005515//protein binding;GO:0010309//acireductone dioxygenase [iron(II)-requiring] activity;GO:0016491//oxidoreductase activity,K08967//Cysteine and methionine metabolism;Metabolic pathways
55258,0,0,0,5,35,29,0,0,56,0,0,0,THNSL2;threonine synthase-like 2 (S. cerevisiae),GO:0005615//extracellular space,GO:0046360//2-oxobutyrate biosynthetic process;GO:0009071//serine family amino acid catabolic process;GO:0016311//dephosphorylation,GO:0005125//cytokine activity;GO:0070905//serine binding;GO:0016829//lyase activity;GO:0030170//pyridoxal phosphate binding,-
55259,0,0,0,0,1,0,0,1,13,0,0,0,CASC1;cancer susceptibility candidate 1,-,-,-,-
5526,1,33,0,0,7,0,0,1,40,0,7,0,"PPP2R5B;protein phosphatase 2, regulatory subunit B', beta",GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process,GO:0008601//protein phosphatase type 2A regulator activity;GO:0005515//protein binding,K11584//Dopaminergic synapse;Wnt signaling pathway;Oocyte meiosis;Meiosis - yeast;mRNA surveillance pathway
55260,0,0,0,0,0,0,0,243,5,0,0,0,TMEM143;transmembrane protein 143,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0002244//hematopoietic progenitor cell differentiation,-,-
55262,0,0,0,0,0,32,0,36,10,195,0,0,C7orf43;chromosome 7 open reading frame 43,-,-,-,-
55266,0,0,0,0,12,14,19,0,66,0,0,0,TMEM19;transmembrane protein 19,GO:0016021//integral component of membrane,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
55267,0,38,0,18,35,26,0,3,20,0,22,0,PRR34;proline rich 34,-,-,-,-
55268,0,17,65,34,53,7,15,65,7,96,79,0,ECHDC2;enoyl CoA hydratase domain containing 2,GO:0005739//mitochondrion,GO:0006631//fatty acid metabolic process,GO:0016829//lyase activity,"K05607//Metabolic pathways;Valine, leucine and isoleucine degradation"
55269,26,0,0,2,40,0,0,0,0,0,0,0,PSPC1;paraspeckle component 1,GO:0016363//nuclear matrix;GO:0042382//paraspeckles;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005730//nucleolus,"GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048511//rhythmic process;GO:0006351//transcription, DNA-templated",GO:0001047//core promoter binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
5527,0,1,1,28,132,10,8,0,55,0,12,0,"PPP2R5C;protein phosphatase 2, regulatory subunit B', gamma","GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region","GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0050790//regulation of catalytic activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction",GO:0008601//protein phosphatase type 2A regulator activity;GO:0005515//protein binding,K11584//mRNA surveillance pathway;Dopaminergic synapse;Meiosis - yeast;Oocyte meiosis;Wnt signaling pathway
55270,0,108,0,53,224,0,23,139,53,135,145,3,NUDT15;nudix (nucleoside diphosphate linked moiety X)-type motif 15,GO:0005829//cytosol,GO:0006184//GTP catabolic process;GO:0006203//dGTP catabolic process;GO:0044281//small molecule metabolic process;GO:0034656//nucleobase-containing small molecule catabolic process,"GO:0008413//8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity;GO:0046872//metal ion binding;GO:0035539//8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity",K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
55272,0,0,0,0,59,0,0,0,0,0,0,0,"IMP3;IMP3, U3 small nucleolar ribonucleoprotein",GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019843//rRNA binding,K14560//Ribosome biogenesis in eukaryotes
55273,72,0,0,0,0,0,1,0,0,0,0,0,TMEM100;transmembrane protein 100,GO:0043204//perikaryon;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm,GO:0001701//in utero embryonic development;GO:0043491//protein kinase B signaling;GO:0071773//cellular response to BMP stimulus;GO:0060842//arterial endothelial cell differentiation;GO:0001570//vasculogenesis;GO:0001525//angiogenesis;GO:0007219//Notch signaling pathway;GO:2001214//positive regulation of vasculogenesis;GO:0045603//positive regulation of endothelial cell differentiation;GO:0030509//BMP signaling pathway,-,-
55274,0,128,48,200,139,6,43,0,13,0,51,0,PHF10;PHD finger protein 10,GO:0071564//npBAF complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development",GO:0008270//zinc ion binding,-
55275,114,0,0,14,46,18,0,1,38,0,0,0,VPS53;vacuolar protein sorting 53 homolog (S. cerevisiae),GO:0010008//endosome membrane;GO:0000938//GARP complex,GO:0015031//protein transport,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
55276,0,1,0,12,29,35,15,62,53,0,0,1,PGM2;phosphoglucomutase 2,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0019388//galactose catabolic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0005980//glycogen catabolic process;GO:0046386//deoxyribose phosphate catabolic process;GO:0006006//glucose metabolic process,GO:0008973//phosphopentomutase activity;GO:0000287//magnesium ion binding;GO:0004614//phosphoglucomutase activity,K15779//Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Glycolysis / Gluconeogenesis;Purine metabolism;Pentose phosphate pathway;Galactose metabolism;Metabolic pathways
55277,0,0,0,8,14,0,0,41,23,0,0,0,FGGY;FGGY carbohydrate kinase domain containing,-,GO:0016310//phosphorylation;GO:0070050//neuron cellular homeostasis;GO:0005975//carbohydrate metabolic process;GO:0008219//cell death,"GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0016301//kinase activity",K00864//Plant-pathogen interaction;PPAR signaling pathway;Glycerolipid metabolism;Metabolic pathways
55278,1,0,1,0,0,15,0,0,0,253,8,0,QRSL1;glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1,GO:0030956//glutamyl-tRNA(Gln) amidotransferase complex;GO:0005739//mitochondrion,GO:0070681//glutaminyl-tRNAGln biosynthesis via transamidation;GO:0032543//mitochondrial translation,GO:0050567//glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity;GO:0005524//ATP binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01426//Microbial metabolism in diverse environments;Styrene degradation;Tryptophan metabolism;Phenylalanine metabolism;Cyanoamino acid metabolism;Arginine and proline metabolism;Aminobenzoate degradation;K11447//Transcriptional misregulation in cancer;K02433//Metabolic pathways;Aminoacyl-tRNA biosynthesis
55279,0,44,0,21,52,0,12,0,47,214,16,2,ZNF654;zinc finger protein 654,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
5528,69,221,0,142,609,43,16,58,21,79,188,1,"PPP2R5D;protein phosphatase 2, regulatory subunit B', delta",GO:0000159//protein phosphatase type 2A complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0016311//dephosphorylation;GO:0002224//toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0007399//nervous system development;GO:0006112//energy reserve metabolic process;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0050790//regulation of catalytic activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0005975//carbohydrate metabolic process,GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,K11584//mRNA surveillance pathway;Dopaminergic synapse;Wnt signaling pathway;Meiosis - yeast;Oocyte meiosis
55280,0,0,0,0,12,0,0,0,30,84,0,0,"CWF19L1;CWF19-like 1, cell cycle control (S. pombe)",-,GO:0008152//metabolic process,GO:0003824//catalytic activity,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
55281,1,1027,424,890,1435,0,54,319,81,2,1571,2,TMEM140;transmembrane protein 140,GO:0016021//integral component of membrane,-,-,-
55282,0,0,0,0,0,0,0,0,8,0,0,0,LRRC36;leucine rich repeat containing 36,-,-,-,K11092//Spliceosome
55283,0,0,0,0,0,0,0,29,22,0,7,0,MCOLN3;mucolipin 3,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:0042491//auditory receptor cell differentiation;GO:0007626//locomotory behavior,-,-
55284,0,41,0,73,55,0,28,0,37,3,0,0,UBE2W;ubiquitin-conjugating enzyme E2W (putative),GO:0005634//nucleus,GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006281//DNA repair;GO:0006513//protein monoubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0071218//cellular response to misfolded protein,GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K10688//Ubiquitin mediated proteolysis
55285,0,12,0,19,86,43,0,0,40,0,0,0,RBM41;RNA binding motif protein 41,-,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
55286,0,0,4,0,0,4,0,0,12,0,5,0,C4orf19;chromosome 4 open reading frame 19,-,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
55287,0,0,0,0,0,0,0,0,4,0,12,272,TMEM40;transmembrane protein 40,GO:0016021//integral component of membrane,-,-,-
55288,0,0,1,23,63,0,25,114,36,0,0,0,RHOT1;ras homolog family member T1,GO:0031307//integral component of mitochondrial outer membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0097345//mitochondrial outer membrane permeabilization;GO:0019725//cellular homeostasis;GO:0047497//mitochondrion transport along microtubule;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
552889,82,182,11,130,348,0,0,32,12,0,0,0,ATXN7L3B;ataxin 7-like 3B,-,-,-,-
55289,212,17,0,2,5,0,0,0,80,0,9,78,ACOXL;acyl-CoA oxidase-like,GO:0005777//peroxisome,GO:0006635//fatty acid beta-oxidation,GO:0003997//acyl-CoA oxidase activity;GO:0003995//acyl-CoA dehydrogenase activity,"K00232//Fatty acid metabolism;Biosynthesis of unsaturated fatty acids;Valine, leucine and isoleucine degradation;Metabolic pathways;beta-Alanine metabolism;Propanoate metabolism;Peroxisome;alpha-Linolenic acid metabolism;PPAR signaling pathway"
5529,0,2,0,16,64,30,52,0,3,60,0,0,"PPP2R5E;protein phosphatase 2, regulatory subunit B', epsilon isoform",GO:0000159//protein phosphatase type 2A complex;GO:0005737//cytoplasm,GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity,K11584//Wnt signaling pathway;Meiosis - yeast;Oocyte meiosis;Dopaminergic synapse;mRNA surveillance pathway
55290,66,0,0,5,38,0,0,0,31,0,6,0,"BRF2;BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit",GO:0005654//nucleoplasm,"GO:0006383//transcription from RNA polymerase III promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression",GO:0008270//zinc ion binding,-
55291,99,2,1,52,163,0,24,0,50,154,0,0,"PPP6R3;protein phosphatase 6, regulatory subunit 3",GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043666//regulation of phosphoprotein phosphatase activity,GO:0019903//protein phosphatase binding;GO:0005515//protein binding,-
55293,0,0,0,0,37,0,0,0,29,0,12,0,UEVLD;UEV and lactate/malate dehyrogenase domains,GO:0070062//extracellular vesicular exosome,GO:0015031//protein transport;GO:0044262//cellular carbohydrate metabolic process;GO:0055114//oxidation-reduction process;GO:0006464//cellular protein modification process,"GO:0016616//oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor",K00016//Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Propanoate metabolism;Microbial metabolism in diverse environments;Pyruvate metabolism;Metabolic pathways;K12183//Endocytosis
55294,0,8,0,0,29,0,0,0,27,0,0,0,"FBXW7;F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase",GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0019005//SCF ubiquitin ligase complex;GO:0005634//nucleus,"GO:0007062//sister chromatid cohesion;GO:0030324//lung development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000346//negative regulation of hepatocyte proliferation;GO:0045746//negative regulation of Notch signaling pathway;GO:0001944//vasculature development;GO:0016032//viral process;GO:0006974//cellular response to DNA damage stimulus;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0032876//negative regulation of DNA endoreduplication;GO:0007219//Notch signaling pathway;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0034644//cellular response to UV;GO:0010868//negative regulation of triglyceride biosynthetic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0016567//protein ubiquitination;GO:0050821//protein stabilization;GO:0032880//regulation of protein localization;GO:0055088//lipid homeostasis;GO:0010883//regulation of lipid storage;GO:2000639//negative regulation of SREBP signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0001570//vasculogenesis","GO:0042802//identical protein binding;GO:0030674//protein binding, bridging;GO:0031625//ubiquitin protein ligase binding;GO:0030332//cyclin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding",K10260//Ubiquitin mediated proteolysis
55295,120,0,0,0,0,7,0,0,0,0,0,0,KLHL26;kelch-like family member 26,-,-,-,-
55296,0,0,0,0,15,15,0,0,30,0,8,0,"TBC1D19;TBC1 domain family, member 19",-,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity,-
55297,0,0,0,9,30,9,3,0,15,0,0,0,CCDC91;coiled-coil domain containing 91,GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0015031//protein transport,GO:0042802//identical protein binding,K11423//Lysine degradation
55298,0,0,0,0,0,0,13,0,0,0,0,0,RNF121;ring finger protein 121,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
55299,0,0,0,1,19,0,0,0,0,0,2,0,"BRIX1;BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)",GO:0005634//nucleus;GO:0005730//nucleolus,GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding,-
5530,123,175,1,216,648,4,0,81,15,0,25,328,"PPP3CA;protein phosphatase 3, catalytic subunit, alpha isozyme",GO:0005955//calcineurin complex;GO:0030018//Z disc;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0042383//sarcolemma;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0046676//negative regulation of insulin secretion;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0033173//calcineurin-NFAT signaling cascade;GO:0071333//cellular response to glucose stimulus;GO:0051592//response to calcium ion;GO:0033555//multicellular organismal response to stress;GO:0006470//protein dephosphorylation;GO:0050804//regulation of synaptic transmission;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006606//protein import into nucleus;GO:0001975//response to amphetamine;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006816//calcium ion transport;GO:0042110//T cell activation;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0035690//cellular response to drug;GO:0016311//dephosphorylation;GO:0048741//skeletal muscle fiber development;GO:0014883//transition between fast and slow fiber;GO:0045087//innate immune response,GO:0046983//protein dimerization activity;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,K04348//Long-term potentiation;Tuberculosis;Dopaminergic synapse;Axon guidance;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;Glutamatergic synapse;Amphetamine addiction;T cell receptor signaling pathway;Apoptosis;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation
55300,0,58,0,17,42,17,6,0,4,0,0,0,PI4K2B;phosphatidylinositol 4-kinase type 2 beta,GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0006644//phospholipid metabolic process,GO:0005524//ATP binding;GO:0004430//1-phosphatidylinositol 4-kinase activity,K13711//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
55301,0,0,0,0,0,0,0,0,0,0,2,0,OLAH;oleoyl-ACP hydrolase,-,GO:0006633//fatty acid biosynthetic process,GO:0016295//myristoyl-[acyl-carrier-protein] hydrolase activity;GO:0016296//palmitoyl-[acyl-carrier-protein] hydrolase activity;GO:0004320//oleoyl-[acyl-carrier-protein] hydrolase activity,K01071//Metabolic pathways;Fatty acid biosynthesis
55303,86,0,0,0,0,6,0,0,36,0,0,0,"GIMAP4;GTPase, IMAP family member 4",GO:0005829//cytosol,-,GO:0005525//GTP binding,K05305//Amino sugar and nucleotide sugar metabolism;Fructose and mannose metabolism;Metabolic pathways
55304,0,0,1,15,1,0,0,0,56,0,0,0,"SPTLC3;serine palmitoyltransferase, long chain base subunit 3",GO:0016021//integral component of membrane;GO:0017059//serine C-palmitoyltransferase complex;GO:0005789//endoplasmic reticulum membrane,GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0046520//sphingoid biosynthetic process;GO:0030148//sphingolipid biosynthetic process,GO:0004758//serine C-palmitoyltransferase activity;GO:0030170//pyridoxal phosphate binding,K00654//Metabolic pathways;Sphingolipid metabolism
55308,0,79,2,6,16,0,0,2,0,0,0,0,DDX19A;DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A,GO:0005737//cytoplasm;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0016020//membrane,GO:0051028//mRNA transport;GO:0010043//response to zinc ion;GO:0043065//positive regulation of apoptotic process;GO:0008152//metabolic process;GO:0015031//protein transport,GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004386//helicase activity,K13025//mRNA surveillance pathway;RNA transport;Spliceosome;K03257//RNA transport;K01529//Purine metabolism
5531,0,0,1,0,0,0,0,13,51,0,0,1,"PPP4C;protein phosphatase 4, catalytic subunit",GO:0005886//plasma membrane;GO:0030289//protein phosphatase 4 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0038061//NIK/NF-kappaB signaling;GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004704//NF-kappaB-inducing kinase activity;GO:0004722//protein serine/threonine phosphatase activity,-
55311,0,0,1,0,0,0,0,0,10,0,0,0,ZNF444;zinc finger protein 444,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
553115,0,73,0,8,43,0,0,0,25,0,0,0,PEF1;penta-EF-hand domain containing 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0051592//response to calcium ion;GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0046983//protein dimerization activity;GO:0046982//protein heterodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,K07359//Alcoholism;Adipocytokine signaling pathway;K01367//Apoptosis;Protein processing in endoplasmic reticulum;Alzheimer's disease
55312,0,44,0,105,169,0,0,0,30,0,23,0,RFK;riboflavin kinase,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0006767//water-soluble vitamin metabolic process;GO:0072593//reactive oxygen species metabolic process;GO:0044281//small molecule metabolic process;GO:0033864//positive regulation of NAD(P)H oxidase activity;GO:0016310//phosphorylation;GO:0009398//FMN biosynthetic process;GO:0006771//riboflavin metabolic process;GO:0006915//apoptotic process;GO:0009231//riboflavin biosynthetic process;GO:0006766//vitamin metabolic process,GO:0008531//riboflavin kinase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,K00861//Riboflavin metabolism;Metabolic pathways
55313,56,0,0,10,38,42,61,0,26,0,23,0,CPPED1;calcineurin-like phosphoesterase domain containing 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0004721//phosphoprotein phosphatase activity,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
55314,0,0,0,9,0,12,0,0,37,0,0,0,TMEM144;transmembrane protein 144,GO:0016021//integral component of membrane,-,-,-
55315,0,0,0,0,0,0,0,0,19,0,0,0,"SLC29A3;solute carrier family 29 (equilibrative nucleoside transporter), member 3",GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0005765//lysosomal membrane,GO:0055085//transmembrane transport;GO:1901642//nucleoside transmembrane transport,GO:0005337//nucleoside transmembrane transporter activity,K15014//Alcoholism
55316,0,0,0,0,13,5,0,0,0,0,4,0,RSAD1;radical S-adenosyl methionine domain containing 1,GO:0005739//mitochondrion,GO:0006779//porphyrin-containing compound biosynthetic process;GO:0055114//oxidation-reduction process,"GO:0051539//4 iron, 4 sulfur cluster binding;GO:0004109//coproporphyrinogen oxidase activity;GO:0046872//metal ion binding",-
55317,0,0,0,0,0,0,0,0,11,0,0,0,"AP5S1;adaptor-related protein complex 5, sigma 1 subunit",GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0005764//lysosome;GO:0030119//AP-type membrane coat adaptor complex;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0005829//cytosol,GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0000724//double-strand break repair via homologous recombination,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
55319,0,47,0,0,14,31,0,0,38,0,0,0,TMA16;translation machinery associated 16 homolog (S. cerevisiae),GO:0005634//nucleus,-,-,-
5532,0,34,0,45,142,55,0,0,37,0,26,0,"PPP3CB;protein phosphatase 3, catalytic subunit, beta isozyme",GO:0005654//nucleoplasm;GO:0005955//calcineurin complex;GO:0005886//plasma membrane;GO:0005829//cytosol,"GO:0017156//calcium ion-dependent exocytosis;GO:0016311//dephosphorylation;GO:0035690//cellular response to drug;GO:0048167//regulation of synaptic plasticity;GO:0048675//axon extension;GO:0050796//regulation of insulin secretion;GO:0031987//locomotion involved in locomotory behavior;GO:0007612//learning;GO:0042110//T cell activation;GO:0045087//innate immune response;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042098//T cell proliferation;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0007507//heart development;GO:0043029//T cell homeostasis;GO:0030217//T cell differentiation;GO:0035176//social behavior;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0006470//protein dephosphorylation;GO:0034097//response to cytokine;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0007613//memory;GO:0007165//signal transduction",GO:0019899//enzyme binding;GO:0008144//drug binding;GO:0005516//calmodulin binding;GO:0030346//protein phosphatase 2B binding;GO:0046983//protein dimerization activity;GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,K04348//MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Amphetamine addiction;Apoptosis;T cell receptor signaling pathway;Glutamatergic synapse;Oocyte meiosis;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Dopaminergic synapse;Axon guidance;Tuberculosis;Long-term potentiation;Osteoclast differentiation;Alzheimer's disease;VEGF signaling pathway;HTLV-I infection;Calcium signaling pathway;B cell receptor signaling pathway
55320,0,0,0,4,0,18,43,31,28,0,0,0,MIS18BP1;MIS18 binding protein 1,"GO:0005654//nucleoplasm;GO:0000775//chromosome, centromeric region",GO:0007067//mitotic nuclear division;GO:0034080//CENP-A containing nucleosome assembly;GO:0006334//nucleosome assembly,GO:0003677//DNA binding;GO:0003682//chromatin binding,-
55321,0,0,0,4,12,0,0,75,28,115,0,0,TMEM74B;transmembrane protein 74B,GO:0016021//integral component of membrane,-,-,-
55322,0,21,0,24,89,28,0,0,42,0,7,0,C5orf22;chromosome 5 open reading frame 22,-,-,-,-
55323,0,0,0,9,15,0,0,0,4,0,0,0,"LARP6;La ribonucleoprotein domain family, member 6",GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006417//regulation of translation;GO:0006396//RNA processing,GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
55324,0,7,19,13,1,0,58,0,37,136,9,11,"ABCF3;ATP-binding cassette, sub-family F (GCN20), member 3",GO:0016020//membrane,GO:0051607//defense response to virus;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity,-
55325,127,503,525,1160,549,0,1,93,39,0,1573,308,UFSP2;UFM1-specific peptidase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum,GO:0006508//proteolysis,GO:0019783//small conjugating protein-specific protease activity;GO:0016790//thiolester hydrolase activity,-
55326,125,0,0,0,0,9,5,0,7,0,0,0,AGPAT5;1-acylglycerol-3-phosphate O-acyltransferase 5,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope,GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0044281//small molecule metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13523//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism;K13513//Glycerophospholipid metabolism;Glycerolipid metabolism;Metabolic pathways
55327,0,21,22,69,209,0,14,0,44,121,0,0,LIN7C;lin-7 homolog C (C. elegans),GO:0043005//neuron projection;GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0014069//postsynaptic density;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0005923//tight junction;GO:0097025//MPP7-DLG1-LIN7 complex,GO:0006887//exocytosis;GO:0002011//morphogenesis of an epithelial sheet;GO:0015031//protein transport;GO:0007269//neurotransmitter secretion,GO:0030165//PDZ domain binding;GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding;GO:0097016//L27 domain binding,-
55328,0,28,55,2,34,0,0,826,72,138,111,1,"RNLS;renalase, FAD-dependent amine oxidase",GO:0005615//extracellular space,GO:0042414//epinephrine metabolic process;GO:1902074//response to salt;GO:0071871//response to epinephrine;GO:0003214//cardiac left ventricle morphogenesis;GO:0071873//response to norepinephrine;GO:0060047//heart contraction;GO:0055114//oxidation-reduction process;GO:0002931//response to ischemia;GO:0042417//dopamine metabolic process;GO:0003073//regulation of systemic arterial blood pressure;GO:0042415//norepinephrine metabolic process;GO:0055062//phosphate ion homeostasis,GO:0016491//oxidoreductase activity,-
55329,0,0,0,28,0,0,0,0,11,37,3,0,MNS1;meiosis-specific nuclear structural 1,GO:0005882//intermediate filament;GO:0036126//sperm flagellum;GO:0005635//nuclear envelope;GO:0005930//axoneme,GO:0007126//meiotic nuclear division;GO:0070986//left/right axis specification;GO:0044782//cilium organization,GO:0042802//identical protein binding,-
5533,0,0,0,1,7,0,26,0,10,0,0,1,"PPP3CC;protein phosphatase 3, catalytic subunit, gamma isozyme",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006915//apoptotic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0016311//dephosphorylation;GO:0097193//intrinsic apoptotic signaling pathway,GO:0005516//calmodulin binding;GO:0004721//phosphoprotein phosphatase activity;GO:0046872//metal ion binding,K04348//Axon guidance;Dopaminergic synapse;Long-term potentiation;Tuberculosis;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;Amphetamine addiction;Apoptosis;T cell receptor signaling pathway;Glutamatergic synapse;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;HTLV-I infection;B cell receptor signaling pathway;Calcium signaling pathway;Alzheimer's disease;Osteoclast differentiation;VEGF signaling pathway
55330,0,0,0,0,1,0,0,0,0,0,0,0,"BLOC1S4;biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino",GO:0005737//cytoplasm;GO:0031083//BLOC-1 complex;GO:0005829//cytosol,GO:0008089//anterograde axon cargo transport;GO:0031175//neuron projection development;GO:0006892//post-Golgi vesicle-mediated transport;GO:0032438//melanosome organization;GO:0061024//membrane organization;GO:0048490//anterograde synaptic vesicle transport;GO:0050885//neuromuscular process controlling balance;GO:0070527//platelet aggregation,GO:0005515//protein binding,-
55332,0,0,0,0,0,0,0,0,7,0,0,0,DRAM1;DNA-damage regulated autophagy modulator 1,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005764//lysosome,GO:0006915//apoptotic process;GO:0006914//autophagy;GO:0010506//regulation of autophagy,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
55333,0,25,0,33,162,16,20,0,15,0,0,0,SYNJ2BP;synaptojanin 2 binding protein,GO:0031307//integral component of mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0009986//cell surface,GO:0032927//positive regulation of activin receptor signaling pathway;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0002092//positive regulation of receptor internalization;GO:2000010//positive regulation of protein localization to cell surface;GO:0048312//intracellular distribution of mitochondria,GO:0070699//type II activin receptor binding;GO:0008022//protein C-terminus binding,K11828//Glutamatergic synapse;Cocaine addiction;Huntington's disease;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
55334,0,30,0,34,85,0,3,0,26,0,0,0,"SLC39A9;solute carrier family 39, member 9",GO:0016021//integral component of membrane,GO:0006829//zinc ion transport;GO:0055085//transmembrane transport,GO:0046873//metal ion transmembrane transporter activity,-
55336,0,0,0,8,6,0,0,66,11,58,6,4,FBXL8;F-box and leucine-rich repeat protein 8,-,-,GO:0005515//protein binding,-
55337,0,0,0,0,0,0,0,0,0,0,2,226,C19orf66;chromosome 19 open reading frame 66,-,-,-,K03903//Complement and coagulation cascades
55339,0,0,1,4,49,39,63,0,90,0,8,0,WDR33;WD repeat domain 33,GO:0005634//nucleus;GO:0005581//collagen trimer,GO:0006397//mRNA processing;GO:0007283//spermatogenesis;GO:0006301//postreplication repair,GO:0044822//poly(A) RNA binding,K15542//mRNA surveillance pathway
5534,0,71,1,105,178,62,0,0,25,0,4,0,"PPP3R1;protein phosphatase 3, regulatory subunit B, alpha",GO:0042383//sarcolemma;GO:0005955//calcineurin complex;GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0097193//intrinsic apoptotic signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006470//protein dephosphorylation;GO:0060487//lung epithelial cell differentiation;GO:0006915//apoptotic process;GO:0001837//epithelial to mesenchymal transition;GO:0001569//patterning of blood vessels;GO:0007507//heart development;GO:0051531//NFAT protein import into nucleus;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0045087//innate immune response,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005516//calmodulin binding,K06268//Osteoclast differentiation;Alzheimer's disease;VEGF signaling pathway;HTLV-I infection;Calcium signaling pathway;B cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Apoptosis;Glutamatergic synapse;T cell receptor signaling pathway;Amphetamine addiction;Oocyte meiosis;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Axon guidance;Tuberculosis;Long-term potentiation
55341,0,0,2,8,0,0,0,0,0,0,0,0,LSG1;large 60S subunit nuclear export GTPase 1,GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015030//Cajal body,GO:0015031//protein transport;GO:0042254//ribosome biogenesis;GO:0006184//GTP catabolic process;GO:0051168//nuclear export,GO:0005525//GTP binding;GO:0003924//GTPase activity,K14539//Ribosome biogenesis in eukaryotes
55342,0,56,1,38,26,0,0,1,49,0,21,0,STRBP;spermatid perinuclear RNA binding protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton,GO:0007286//spermatid development;GO:0006928//cellular component movement;GO:0007275//multicellular organismal development;GO:0007638//mechanosensory behavior,GO:0003725//double-stranded RNA binding;GO:0003727//single-stranded RNA binding;GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding,-
55343,0,0,0,0,0,0,23,0,58,0,0,0,"SLC35C1;solute carrier family 35 (GDP-fucose transporter), member C1",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030259//lipid glycosylation;GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport;GO:0045746//negative regulation of Notch signaling pathway,-,-
55344,57,0,0,0,0,0,13,0,16,0,0,0,"PLCXD1;phosphatidylinositol-specific phospholipase C, X domain containing 1",-,GO:0006629//lipid metabolic process,GO:0008081//phosphoric diester hydrolase activity,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
55345,82,0,0,0,15,1,7,0,76,0,8,0,"ZGRF1;zinc finger, GRF-type containing 1",GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,K14326//mRNA surveillance pathway;RNA transport
55346,16,0,0,0,5,24,0,5,40,0,12,0,"TCP11L1;t-complex 11, testis-specific-like 1",GO:0005874//microtubule,-,-,-
55347,0,0,0,8,6,9,0,0,18,0,0,0,ABHD10;abhydrolase domain containing 10,GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0019391//glucuronoside catabolic process,"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",-
55349,16,0,0,11,2,0,0,0,37,0,0,0,CHDH;choline dehydrogenase,GO:0005743//mitochondrial inner membrane,GO:0019285//glycine betaine biosynthetic process from choline;GO:0055114//oxidation-reduction process,GO:0008812//choline dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding,"K00108//Glycine, serine and threonine metabolism"
5535,0,0,0,0,0,0,0,116,2,18,0,0,"PPP3R2;protein phosphatase 3, regulatory subunit B, beta",-,-,GO:0005509//calcium ion binding,K06268//B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation;Long-term potentiation;Tuberculosis;Axon guidance;Oocyte meiosis;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Apoptosis;Amphetamine addiction;T cell receptor signaling pathway;Glutamatergic synapse
55350,0,0,0,0,0,18,0,0,5,0,6,0,VNN3;vanin 3,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0006807//nitrogen compound metabolic process,GO:0017159//pantetheine hydrolase activity,K08069//Pantothenate and CoA biosynthesis
55351,91,0,0,0,0,0,0,0,69,0,0,0,STK32B;serine/threonine kinase 32B,-,GO:0006468//protein phosphorylation,GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
55352,0,16,0,10,35,14,0,0,0,0,0,0,"COPRS;coordinator of PRMT5, differentiation stimulator",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane,"GO:0007517//muscle organ development;GO:0043985//histone H4-R3 methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0042393//histone binding;GO:0005515//protein binding,-
55353,0,0,0,0,0,10,11,0,1,0,0,0,LAPTM4B;lysosomal protein transmembrane 4 beta,GO:0012505//endomembrane system;GO:0016021//integral component of membrane,GO:0006810//transport,GO:0005515//protein binding,K12387//Lysosome
55355,88,0,0,0,0,0,0,0,0,0,0,0,HJURP;Holliday junction recognition protein,"GO:0005737//cytoplasm;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0000777//condensed chromosome kinetochore",GO:0043254//regulation of protein complex assembly;GO:0051101//regulation of DNA binding;GO:0006334//nucleosome assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0007059//chromosome segregation;GO:0007049//cell cycle,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042393//histone binding;GO:0003677//DNA binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion
55356,0,0,0,0,0,28,22,0,10,0,0,1,"SLC22A15;solute carrier family 22, member 15",GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,-
55357,0,0,0,0,6,9,59,0,32,0,0,0,"TBC1D2;TBC1 domain family, member 2",GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030054//cell junction;GO:0031410//cytoplasmic vesicle,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity;GO:0045296//cadherin binding,-
55359,0,0,0,0,0,0,19,0,0,0,0,0,STYK1;serine/threonine/tyrosine kinase 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0018108//peptidyl-tyrosine phosphorylation,GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding,-
5536,0,0,0,0,42,0,0,0,22,0,0,0,"PPP5C;protein phosphatase 5, catalytic subunit",GO:0005634//nucleus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0016020//membrane,"GO:0051291//protein heterooligomerization;GO:0006470//protein dephosphorylation;GO:0006351//transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006281//DNA repair;GO:0007067//mitotic nuclear division;GO:0007165//signal transduction;GO:0008219//cell death;GO:0043278//response to morphine",GO:0008289//lipid binding;GO:0003723//RNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004871//signal transducer activity;GO:0042802//identical protein binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K04460//MAPK signaling pathway
55361,74,31,0,10,28,0,0,0,76,0,16,0,PI4K2A;phosphatidylinositol 4-kinase type 2 alpha,GO:0005887//integral component of plasma membrane;GO:0043204//perikaryon;GO:0005765//lysosomal membrane;GO:0044231//host cell presynaptic membrane;GO:0005768//endosome;GO:0030425//dendrite;GO:0043005//neuron projection;GO:0016020//membrane;GO:0070382//exocytic vesicle;GO:0005829//cytosol;GO:0035838//growing cell tip;GO:0005739//mitochondrion;GO:0031901//early endosome membrane;GO:0031083//BLOC-1 complex;GO:0043025//neuronal cell body;GO:0031410//cytoplasmic vesicle;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0042734//presynaptic membrane;GO:0030672//synaptic vesicle membrane;GO:0045121//membrane raft,GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004430//1-phosphatidylinositol 4-kinase activity;GO:0035651//AP-3 adaptor complex binding;GO:0005515//protein binding,K13711//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
55362,66,336,21,185,367,21,24,714,236,0,301,0,TMEM63B;transmembrane protein 63B,GO:0016021//integral component of membrane,GO:0006811//ion transport,GO:0000166//nucleotide binding,K00728//Other types of O-glycan biosynthesis
55363,279,0,0,0,0,24,0,0,24,0,0,0,HEMGN;hemogen,GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0005515//protein binding,-
55364,0,59,0,108,165,15,0,0,73,0,0,0,IMPACT;impact RWD domain protein,GO:0005737//cytoplasm,GO:0006446//regulation of translational initiation;GO:0001933//negative regulation of protein phosphorylation,-,-
55366,0,0,0,16,1,36,13,0,0,152,0,0,LGR4;leucine-rich repeat containing G protein-coupled receptor 4,GO:0005887//integral component of plasma membrane,"GO:0030539//male genitalia development;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0050673//epithelial cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050710//negative regulation of cytokine secretion;GO:0045087//innate immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0072224//metanephric glomerulus development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001649//osteoblast differentiation;GO:0072282//metanephric nephron tubule morphogenesis;GO:0046849//bone remodeling;GO:0030282//bone mineralization;GO:0007283//spermatogenesis;GO:0061290//canonical Wnt signaling pathway involved in metanephric kidney development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0072202//cell differentiation involved in metanephros development",GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004930//G-protein coupled receptor activity,-
55367,0,3,19,0,0,8,0,0,24,0,0,0,PIDD1;p53-induced death domain protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus,"GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006974//cellular response to DNA damage stimulus;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process",GO:0005515//protein binding;GO:0005123//death receptor binding,K10130//NF-kappa B signaling pathway;p53 signaling pathway
5537,0,24,0,39,148,0,0,0,8,0,0,0,"PPP6C;protein phosphatase 6, catalytic subunit",GO:0005829//cytosol,GO:0000082//G1/S transition of mitotic cell cycle;GO:0006470//protein dephosphorylation,GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
55370,0,0,0,0,0,30,30,0,11,0,0,333,"PPP4R1L;protein phosphatase 4, regulatory subunit 1-like",-,-,-,-
55379,0,18,34,32,28,25,0,1,0,0,0,0,LRRC59;leucine rich repeat containing 59,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0042645//mitochondrial nucleoid;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane,-,GO:0044822//poly(A) RNA binding,K01768//Meiosis - yeast;Purine metabolism;K10130//p53 signaling pathway;NF-kappa B signaling pathway;K12603//RNA degradation
5538,0,0,0,6,17,0,20,0,0,0,0,0,PPT1;palmitoyl-protein thioesterase 1,GO:0005634//nucleus;GO:0005764//lysosome;GO:0030424//axon;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0043025//neuronal cell body;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0045121//membrane raft,GO:0007601//visual perception;GO:0031579//membrane raft organization;GO:0007042//lysosomal lumen acidification;GO:0030163//protein catabolic process;GO:0002084//protein depalmitoylation;GO:0008344//adult locomotory behavior;GO:0043524//negative regulation of neuron apoptotic process;GO:0007625//grooming behavior;GO:0007399//nervous system development;GO:0051181//cofactor transport;GO:0006898//receptor-mediated endocytosis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0048666//neuron development;GO:0032429//regulation of phospholipase A2 activity;GO:0030149//sphingolipid catabolic process;GO:0051186//cofactor metabolic process;GO:0008219//cell death;GO:0016042//lipid catabolic process;GO:0043066//negative regulation of apoptotic process;GO:0015031//protein transport;GO:0008306//associative learning;GO:0007269//neurotransmitter secretion;GO:0007420//brain development;GO:0030308//negative regulation of cell growth;GO:0050803//regulation of synapse structure and activity;GO:0044257//cellular protein catabolic process;GO:0048549//positive regulation of pinocytosis;GO:0006907//pinocytosis,GO:0008474//palmitoyl-(protein) hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity,K01074//Lysosome;Fatty acid elongation;Metabolic pathways
55388,84,0,0,0,0,21,0,51,56,0,0,654,MCM10;minichromosome maintenance complex component 10,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000082//G1/S transition of mitotic cell cycle;GO:0008283//cell proliferation;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0003677//DNA binding,-
554,0,0,0,0,0,10,0,0,7,0,0,0,AVPR2;arginine vasopressin receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0008284//positive regulation of cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007588//excretion;GO:0007190//activation of adenylate cyclase activity;GO:0010628//positive regulation of gene expression;GO:0055085//transmembrane transport;GO:0035814//negative regulation of renal sodium excretion;GO:0007599//hemostasis;GO:0021537//telencephalon development;GO:0006833//water transport;GO:0031398//positive regulation of protein ubiquitination;GO:0034097//response to cytokine;GO:0035811//negative regulation of urine volume;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0032609//interferon-gamma production,GO:0005000//vasopressin receptor activity;GO:0005515//protein binding,K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction
5540,0,0,0,0,0,0,0,0,0,0,11,0,NPY4R;neuropeptide Y receptor Y4,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007586//digestion;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0008015//blood circulation;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0042277//peptide binding;GO:0001602//pancreatic polypeptide receptor activity;GO:0001601//peptide YY receptor activity,K04204//Neuroactive ligand-receptor interaction
5542,0,0,0,0,0,0,0,38,0,0,11,139,PRB1;proline-rich protein BstNI subfamily 1,GO:0005576//extracellular region,-,-,K12797//NOD-like receptor signaling pathway;K13911//Salivary secretion
554201,0,0,0,0,0,0,0,0,12,56,0,0,CCDC148-AS1;CCDC148 antisense RNA 1,-,-,-,-
554203,0,0,0,0,1,24,0,62,0,0,0,0,"JPX;JPX transcript, XIST activator (non-protein coding)",-,-,-,K07050//Aminoacyl-tRNA biosynthesis
55421,0,1,37,27,57,0,0,0,38,21,0,0,C17orf85;chromosome 17 open reading frame 85,-,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
55422,0,32,0,26,91,0,0,0,33,0,0,0,ZNF331;zinc finger protein 331,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
554223,0,0,1,0,0,0,0,0,0,0,0,0,LOC554223;histocompatibility antigen-related,-,-,-,K06751//Phagosome;Autoimmune thyroid disease;Endocytosis;HTLV-I infection;Type I diabetes mellitus;Allograft rejection;Viral myocarditis;Graft-versus-host disease;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Epstein-Barr virus infection;Antigen processing and presentation
55423,0,0,0,0,0,0,0,0,14,0,0,0,SIRPG;signal-regulatory protein gamma,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007596//blood coagulation;GO:0022409//positive regulation of cell-cell adhesion;GO:0007155//cell adhesion;GO:0035556//intracellular signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0050870//positive regulation of T cell activation;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0050900//leukocyte migration,GO:0005515//protein binding,K06551//Osteoclast differentiation
554235,0,0,0,0,0,0,0,74,7,0,14,0,ASPDH;aspartate dehydrogenase domain containing,-,GO:0006742//NADP catabolic process;GO:0055114//oxidation-reduction process;GO:0009435//NAD biosynthetic process,GO:0050661//NADP binding;GO:0033735//aspartate dehydrogenase activity,-
554236,98,0,0,0,0,10,46,0,20,0,7,0,DPY19L2P1;DPY19L2 pseudogene 1,GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
55425,0,0,0,1,34,0,1,0,9,72,0,0,GPALPP1;GPALPP motifs containing 1,-,-,-,K13171//RNA transport;mRNA surveillance pathway
554251,0,0,0,0,0,0,0,0,14,0,0,0,FBXO48;F-box protein 48,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
55432,40,0,37,16,33,19,24,0,6,0,0,0,YOD1;YOD1 deubiquitinase,-,GO:1990167//protein K27-linked deubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0035523//protein K29-linked deubiquitination;GO:1990168//protein K33-linked deubiquitination;GO:0006520//cellular amino acid metabolic process;GO:0035871//protein K11-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0070536//protein K63-linked deubiquitination,GO:1990380//Lys48-specific deubiquitinase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K13719//Protein processing in endoplasmic reticulum
55435,0,8,0,23,94,0,0,0,30,0,22,0,AP1AR;adaptor-related protein complex 1 associated regulatory protein,GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0005730//nucleolus;GO:0030133//transport vesicle;GO:0005737//cytoplasm,"GO:0001920//negative regulation of receptor recycling;GO:0034315//regulation of Arp2/3 complex-mediated actin nucleation;GO:0048203//vesicle targeting, trans-Golgi to endosome;GO:2000146//negative regulation of cell motility;GO:0034613//cellular protein localization;GO:0015031//protein transport;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading",GO:0035650//AP-1 adaptor complex binding;GO:0019894//kinesin binding,-
55437,0,36,0,5,23,0,31,61,2,0,2,0,STRADB;STE20-related kinase adaptor beta,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0000902//cell morphogenesis;GO:0006611//protein export from nucleus;GO:0008286//insulin receptor signaling pathway;GO:0032147//activation of protein kinase activity;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0007050//cell cycle arrest,GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0005515//protein binding,K08271//mTOR signaling pathway
55449,0,304,25,363,465,0,9,219,29,0,540,1,DHRS4-AS1;DHRS4 antisense RNA 1,-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K11147//Peroxisome;Retinol metabolism;Metabolic pathways
5545,0,0,0,0,0,14,10,0,0,0,0,0,PRB4;proline-rich protein BstNI subfamily 4,GO:0005576//extracellular region,-,-,K13911//Salivary secretion
55450,0,1,0,1,34,8,0,0,0,0,12,0,CAMK2N1;calcium/calmodulin-dependent protein kinase II inhibitor 1,GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body,GO:0006469//negative regulation of protein kinase activity,GO:0019901//protein kinase binding;GO:0008427//calcium-dependent protein kinase inhibitor activity,-
55454,0,0,0,2,16,0,2,0,69,0,0,0,CSGALNACT2;chondroitin sulfate N-acetylgalactosaminyltransferase 2,GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane,"GO:0030166//proteoglycan biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0050652//dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0050653//chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process;GO:0030204//chondroitin sulfate metabolic process",GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0008376//acetylgalactosaminyltransferase activity,K00746//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate
5546,0,14,0,11,0,0,0,0,8,0,0,0,PRCC;papillary renal cell carcinoma (translocation-associated),GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0007093//mitotic cell cycle checkpoint,GO:0005515//protein binding,K13105//Transcriptional misregulation in cancer
55466,4,60,2,187,340,32,0,189,21,0,24,2,"DNAJA4;DnaJ (Hsp40) homolog, subfamily A, member 4",GO:0005829//cytosol;GO:0016020//membrane,GO:0090084//negative regulation of inclusion body assembly;GO:0042026//protein refolding;GO:0009408//response to heat,GO:0051087//chaperone binding;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding,-
5547,0,1,0,22,27,0,1,0,15,0,0,0,PRCP;prolylcarboxypeptidase (angiotensinase C),GO:0045178//basal part of cell;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0006508//proteolysis;GO:0007596//blood coagulation;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0007597//blood coagulation, intrinsic pathway;GO:0097009//energy homeostasis;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0042593//glucose homeostasis;GO:0060055//angiogenesis involved in wound healing",GO:0004185//serine-type carboxypeptidase activity;GO:0005515//protein binding,K01285//Protein digestion and absorption
55471,0,0,0,0,0,4,0,0,19,0,0,0,"NDUFAF7;NADH dehydrogenase (ubiquinone) complex I, assembly factor 7",GO:0005615//extracellular space;GO:0005739//mitochondrion,GO:0032259//methylation;GO:0032981//mitochondrial respiratory chain complex I assembly,GO:0008168//methyltransferase activity;GO:0019899//enzyme binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation
55486,0,0,0,1,36,0,0,0,0,0,0,0,"PARL;presenilin associated, rhomboid-like",GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus,GO:2000377//regulation of reactive oxygen species metabolic process;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0033619//membrane protein proteolysis;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity,-
5549,47,0,0,0,0,7,17,49,5,0,0,0,PRELP;proline/arginine-rich end leucine-rich repeat protein,GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0031982//vesicle;GO:0043202//lysosomal lumen,GO:0042340//keratan sulfate catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0007569//cell aging;GO:0001501//skeletal system development;GO:0018146//keratan sulfate biosynthetic process,GO:0005201//extracellular matrix structural constituent;GO:0008201//heparin binding,-
5550,162,1,0,9,32,19,68,0,22,0,0,272,PREP;prolyl endopeptidase,GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0005515//protein binding;GO:0070008//serine-type exopeptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,-
55500,0,0,0,6,4,0,0,0,35,0,0,0,ETNK1;ethanolamine kinase 1,GO:0005829//cytosol;GO:0016020//membrane,GO:0044281//small molecule metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0016310//phosphorylation;GO:0046474//glycerophospholipid biosynthetic process,GO:0005524//ATP binding;GO:0004305//ethanolamine kinase activity,K00894//Glycerophospholipid metabolism;Metabolic pathways
55501,0,0,0,0,12,10,0,33,9,0,0,0,CHST12;carbohydrate (chondroitin 4) sulfotransferase 12,GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane,GO:0016051//carbohydrate biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0047756//chondroitin 4-sulfotransferase activity,K04742//Glycosaminoglycan biosynthesis - chondroitin sulfate;Sulfur metabolism
55502,71,0,0,0,0,0,0,0,6,0,0,0,HES6;hes family bHLH transcription factor 6,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007399//nervous system development;GO:0006355//regulation of transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003712//transcription cofactor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0008134//transcription factor binding,-
55503,0,35,1,25,49,0,0,50,9,0,2,0,"TRPV6;transient receptor potential cation channel, subfamily V, member 6",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0055085//transmembrane transport;GO:0006816//calcium ion transport,GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005516//calmodulin binding,K04975//Salivary secretion;Mineral absorption
55504,43,144,192,537,49,1,0,89,67,0,711,0,"TNFRSF19;tumor necrosis factor receptor superfamily, member 19",GO:0016021//integral component of membrane,GO:0006915//apoptotic process;GO:0001942//hair follicle development;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007254//JNK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0005031//tumor necrosis factor-activated receptor activity,K05155//Cytokine-cytokine receptor interaction
55505,0,16,0,5,38,0,0,0,11,0,0,0,NOP10;NOP10 ribonucleoprotein,GO:0005730//nucleolus;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0072588//box H/ACA RNP complex;GO:0015030//Cajal body,GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing,GO:0030515//snoRNA binding;GO:0005515//protein binding,K11130//Ribosome biogenesis in eukaryotes
55506,0,0,1,0,12,0,14,1,67,0,0,0,"H2AFY2;H2A histone family, member Y2",GO:0035098//ESC/E(Z) complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0001740//Barr body;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,"GO:0006334//nucleosome assembly;GO:0001558//regulation of cell growth;GO:1901837//negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0016568//chromatin modification;GO:0071169//establishment of protein localization to chromatin;GO:0007549//dosage compensation;GO:0007420//brain development;GO:0045814//negative regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0044212//transcription regulatory region DNA binding;GO:0031490//chromatin DNA binding;GO:0046982//protein heterodimerization activity,K11251//Systemic lupus erythematosus;Alcoholism
55507,0,0,0,9,11,0,0,0,9,0,0,0,"GPRC5D;G protein-coupled receptor, class C, group 5, member D",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
55508,0,0,0,6,0,0,34,0,11,0,0,0,"SLC35E3;solute carrier family 35, member E3",GO:0016021//integral component of membrane,-,-,-
55509,0,0,0,0,0,0,0,0,44,0,0,4,"BATF3;basic leucine zipper transcription factor, ATF-like 3",GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0009615//response to virus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0097028//dendritic cell differentiation;GO:0043011//myeloid dendritic cell differentiation,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
5551,127,0,0,0,0,18,0,0,24,55,0,0,PRF1;perforin 1 (pore forming protein),GO:0031904//endosome lumen;GO:0044194//cytolytic granule;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0055085//transmembrane transport;GO:0006968//cellular defense response;GO:0019835//cytolysis;GO:0006915//apoptotic process;GO:0002357//defense response to tumor cell;GO:0002418//immune response to tumor cell;GO:0051607//defense response to virus;GO:0051260//protein homooligomerization,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0022829//wide pore channel activity,K07818//Autoimmune thyroid disease;Allograft rejection;Graft-versus-host disease;Viral myocarditis;Natural killer cell mediated cytotoxicity;Type I diabetes mellitus
55510,0,0,0,15,1,0,0,0,49,29,0,0,DDX43;DEAD (Asp-Glu-Ala-Asp) box polypeptide 43,GO:0005622//intracellular,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0004004//ATP-dependent RNA helicase activity,K12823//Spliceosome;Transcriptional misregulation in cancer
55511,0,0,0,0,0,16,0,0,34,0,5,0,SAGE1;sarcoma antigen 1,GO:0005730//nucleolus;GO:0005634//nucleus,-,-,-
55512,1,0,0,0,0,39,0,55,43,0,3,1,"SMPD3;sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)",GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0000137//Golgi cis cisterna,GO:0006685//sphingomyelin catabolic process;GO:0006665//sphingolipid metabolic process;GO:0030072//peptide hormone secretion;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007049//cell cycle;GO:0044281//small molecule metabolic process;GO:0006687//glycosphingolipid metabolic process,GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity,K12352//Metabolic pathways;Sphingolipid metabolism
55515,0,0,0,0,0,35,0,69,0,0,0,0,ASIC4;acid-sensing (proton-gated) ion channel family member 4,GO:0005887//integral component of plasma membrane,GO:0035725//sodium ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006810//transport,GO:0005216//ion channel activity;GO:0015081//sodium ion transmembrane transporter activity;GO:0005272//sodium channel activity,-
5552,0,0,0,0,0,0,0,0,0,0,1,0,SRGN;serglycin,GO:0005576//extracellular region;GO:0042588//zymogen granule;GO:0005794//Golgi apparatus;GO:0042629//mast cell granule;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen,GO:0030502//negative regulation of bone mineralization;GO:0050710//negative regulation of cytokine secretion;GO:0016485//protein processing;GO:0031214//biomineral tissue development;GO:0030168//platelet activation;GO:0033364//mast cell secretory granule organization;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0007596//blood coagulation;GO:0033373//maintenance of protease location in mast cell secretory granule;GO:0033382//maintenance of granzyme B location in T cell secretory granule;GO:0002576//platelet degranulation,GO:0005518//collagen binding;GO:0005515//protein binding,-
55520,0,0,10,11,38,24,0,0,0,0,10,308,ELAC1;elaC ribonuclease Z 1,GO:0005634//nucleus;GO:0005829//cytosol,"GO:0042779//tRNA 3'-trailer cleavage;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic","GO:0016891//endoribonuclease activity, producing 5'-phosphomonoesters;GO:0046872//metal ion binding",K00784//RNA transport
55521,0,0,0,0,13,0,0,0,0,0,0,0,TRIM36;tripartite motif containing 36,GO:0070062//extracellular vesicular exosome;GO:0001669//acrosomal vesicle;GO:0005856//cytoskeleton,GO:0016567//protein ubiquitination;GO:0051726//regulation of cell cycle;GO:0007340//acrosome reaction,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
55526,0,56,0,77,175,0,40,12,11,0,0,0,DHTKD1;dehydrogenase E1 and transketolase domain containing 1,GO:0005739//mitochondrion,GO:0006099//tricarboxylic acid cycle;GO:0006096//glycolytic process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006091//generation of precursor metabolites and energy;GO:0008219//cell death,GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976//thiamine pyrophosphate binding,-
55527,0,23,0,18,24,53,1,0,14,2,12,0,FEM1A;fem-1 homolog a (C. elegans),GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0051438//regulation of ubiquitin-protein transferase activity;GO:0050728//negative regulation of inflammatory response,GO:0004842//ubiquitin-protein transferase activity;GO:0031867//EP4 subtype prostaglandin E2 receptor binding,-
55529,0,0,63,2,20,3,0,0,0,0,0,0,TMEM55A;transmembrane protein 55A,GO:0016021//integral component of membrane;GO:0031902//late endosome membrane;GO:0005765//lysosomal membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
5553,0,0,0,0,0,0,0,0,5,0,0,0,"PRG2;proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0030133//transport vesicle,GO:0006955//immune response;GO:0032753//positive regulation of interleukin-4 production;GO:0042742//defense response to bacterium;GO:0032693//negative regulation of interleukin-10 production;GO:0002215//defense response to nematode,GO:0030246//carbohydrate binding;GO:0008201//heparin binding,K10786//Asthma
55530,81,0,0,0,14,0,6,0,102,0,0,0,SVOP;SV2 related protein homolog (rat),GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane,GO:0034220//ion transmembrane transport,GO:0015075//ion transmembrane transporter activity,K06258//ECM-receptor interaction
55531,0,0,0,0,0,0,0,0,17,0,16,0,ELMOD1;ELMO/CED-12 domain containing 1,GO:0005856//cytoskeleton,GO:0006909//phagocytosis;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
55534,0,0,0,8,22,20,19,0,56,0,0,0,MAML3;mastermind-like 3 (Drosophila),GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0007219//Notch signaling pathway,GO:0003713//transcription coactivator activity,K06061//Notch signaling pathway
55536,2,0,0,5,0,0,0,0,42,175,25,2,CDCA7L;cell division cycle associated 7-like,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
55540,0,132,76,258,403,0,9,0,74,0,214,0,IL17RB;interleukin 17 receptor B,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0016020//membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0001558//regulation of cell growth;GO:0006952//defense response,GO:0004896//cytokine receptor activity,K05165//Cytokine-cytokine receptor interaction
55544,0,0,0,0,0,0,0,0,4,0,0,0,RBM38;RNA binding motif protein 38,GO:0005634//nucleus;GO:0005829//cytosol,"GO:0010830//regulation of myotube differentiation;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0008285//negative regulation of cell proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0043484//regulation of RNA splicing;GO:0030154//cell differentiation;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0007050//cell cycle arrest;GO:0007049//cell cycle",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0003729//mRNA binding;GO:0003730//mRNA 3'-UTR binding,K13708//Focal adhesion;Shigellosis;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;K14411//mRNA surveillance pathway
55545,0,0,0,0,0,0,0,0,31,0,9,0,MSX2P1;msh homeobox 2 pseudogene 1,-,-,-,K09341//HTLV-I infection
5555,0,0,0,0,0,0,0,0,11,0,0,0,PRH2;proline-rich protein HaeIII subfamily 2,GO:0005615//extracellular space,-,GO:0005515//protein binding,K13911//Salivary secretion;K13910//Salivary secretion
55552,0,0,0,0,0,0,16,0,23,0,0,0,ZNF823;zinc finger protein 823,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
55553,0,0,23,7,0,8,0,0,68,0,7,0,SOX6;SRY (sex determining region Y)-box 6,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0061036//positive regulation of cartilage development;GO:0009791//post-embryonic development;GO:0016458//gene silencing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0055007//cardiac muscle cell differentiation;GO:0000902//cell morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0032332//positive regulation of chondrocyte differentiation;GO:0051216//cartilage development;GO:0048821//erythrocyte development;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0021778//oligodendrocyte cell fate specification;GO:0001701//in utero embryonic development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0048708//astrocyte differentiation;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding,-
55554,0,0,0,0,0,0,0,0,13,0,1,0,KLK15;kallikrein-related peptidase 15,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
55556,11,19,1,7,30,9,15,74,60,147,20,0,ENOSF1;enolase superfamily member 1,GO:0005739//mitochondrion,GO:0009063//cellular amino acid catabolic process;GO:0044275//cellular carbohydrate catabolic process,GO:0000287//magnesium ion binding;GO:0050023//L-fuconate dehydratase activity;GO:0016853//isomerase activity,K00560//Homologous recombination;Pyrimidine metabolism;One carbon pool by folate;Metabolic pathways
55558,0,2,0,0,0,21,17,27,42,0,8,0,PLXNA3;plexin A3,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0002116//semaphorin receptor complex,GO:0007275//multicellular organismal development;GO:0007411//axon guidance;GO:0021612//facial nerve structural organization;GO:0071526//semaphorin-plexin signaling pathway;GO:0050919//negative chemotaxis;GO:0051495//positive regulation of cytoskeleton organization;GO:0021785//branchiomotor neuron axon guidance;GO:0021766//hippocampus development;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0021860//pyramidal neuron development,GO:0017154//semaphorin receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K06820//Axon guidance
55559,0,0,0,1,0,0,9,0,33,81,0,0,"HAUS7;HAUS augmin-like complex, subunit 7",GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0070652//HAUS complex;GO:0005819//spindle;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0051225//spindle assembly;GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization,GO:0031996//thioesterase binding,-
55561,0,25,0,0,0,0,0,45,18,36,10,0,CDC42BPG;CDC42 binding protein kinase gamma (DMPK-like),GO:0005737//cytoplasm;GO:0031252//cell leading edge,GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0050790//regulation of catalytic activity,GO:0005083//small GTPase regulator activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
55565,0,0,19,0,53,0,0,0,18,0,9,0,ZNF821;zinc finger protein 821,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
55567,0,0,0,0,0,17,50,25,55,182,23,0,"DNAH3;dynein, axonemal, heavy chain 3",GO:0005858//axonemal dynein complex;GO:0005874//microtubule,GO:0008152//metabolic process;GO:0001539//cilium or flagellum-dependent cell motility;GO:0007018//microtubule-based movement,GO:0005524//ATP binding;GO:0003777//microtubule motor activity,K10408//Huntington's disease
55568,0,0,36,0,0,14,0,0,28,0,0,6,GALNT10;polypeptide N-acetylgalactosaminyltransferase 10,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0044267//cellular protein metabolic process,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
5557,0,0,0,15,0,0,17,0,24,0,0,0,"PRIM1;primase, DNA, polypeptide 1 (49kDa)",GO:1990077//primosome complex;GO:0016020//membrane;GO:0005654//nucleoplasm,"GO:0032201//telomere maintenance via semi-conservative replication;GO:0006269//DNA replication, synthesis of RNA primer;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000722//telomere maintenance via recombination;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000723//telomere maintenance",GO:0046872//metal ion binding;GO:0003896//DNA primase activity,K02684//Metabolic pathways;DNA replication;Purine metabolism;Pyrimidine metabolism
55571,0,0,0,17,5,12,0,0,0,0,32,1,"CNOT11;CCR4-NOT transcription complex, subunit 11",GO:0005829//cytosol;GO:0030014//CCR4-NOT complex;GO:0005634//nucleus,"GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0006417//regulation of translation;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0031047//gene silencing by RNA;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0016071//mRNA metabolic process",GO:0005515//protein binding,-
55572,101,0,1,0,17,1,0,50,1,167,2,0,FOXRED1;FAD-dependent oxidoreductase domain containing 1,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,"K00315//Glycine, serine and threonine metabolism;Metabolic pathways;K00314//Metabolic pathways;Glycine, serine and threonine metabolism"
55573,0,0,1,40,176,11,17,0,0,0,20,0,CDV3;CDV3 homolog (mouse),GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0008283//cell proliferation,-,-
55576,63,0,0,6,12,18,20,71,107,1,0,1,STAB2;stabilin 2,GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0042742//defense response to bacterium;GO:0007155//cell adhesion;GO:0006897//endocytosis;GO:0010468//regulation of gene expression;GO:0055114//oxidation-reduction process;GO:0006898//receptor-mediated endocytosis;GO:0030214//hyaluronan catabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030212//hyaluronan metabolic process;GO:0030193//regulation of blood coagulation;GO:0001525//angiogenesis;GO:0005975//carbohydrate metabolic process,GO:0015035//protein disulfide oxidoreductase activity;GO:0005041//low-density lipoprotein receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0005044//scavenger receptor activity,K14616//Vitamin digestion and absorption
55577,0,7,0,0,30,0,0,0,12,85,23,0,NAGK;N-acetylglucosamine kinase,GO:0070062//extracellular vesicular exosome,GO:0006044//N-acetylglucosamine metabolic process;GO:0046835//carbohydrate phosphorylation;GO:0006051//N-acetylmannosamine metabolic process;GO:0019262//N-acetylneuraminate catabolic process,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0045127//N-acetylglucosamine kinase activity,K00884//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
55578,0,4,0,6,46,20,20,39,25,69,0,0,SUPT20H;suppressor of Ty 20 homolog (S. cerevisiae),GO:0070461//SAGA-type complex;GO:0000124//SAGA complex,GO:0006325//chromatin organization;GO:2001141//regulation of RNA biosynthetic process;GO:0007369//gastrulation;GO:0006914//autophagy,GO:0003712//transcription cofactor activity;GO:0005515//protein binding,-
5558,0,0,0,36,89,27,0,0,14,0,2,0,"PRIM2;primase, DNA, polypeptide 2 (58kDa)",GO:1990077//primosome complex;GO:0005654//nucleoplasm,"GO:0000082//G1/S transition of mitotic cell cycle;GO:0006269//DNA replication, synthesis of RNA primer;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000723//telomere maintenance;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000722//telomere maintenance via recombination;GO:0000278//mitotic cell cycle","GO:0046872//metal ion binding;GO:0003896//DNA primase activity;GO:0003677//DNA binding;GO:0051539//4 iron, 4 sulfur cluster binding",K02685//Metabolic pathways;DNA replication;Purine metabolism;Pyrimidine metabolism
55582,71,0,0,1,2,0,47,47,75,0,0,0,KIF27;kinesin family member 27,GO:0005871//kinesin complex;GO:0005929//cilium;GO:0070062//extracellular vesicular exosome;GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0007224//smoothened signaling pathway;GO:0007018//microtubule-based movement;GO:0003351//epithelial cilium movement;GO:0021591//ventricular system development;GO:0006200//ATP catabolic process;GO:0042384//cilium assembly;GO:0008152//metabolic process,GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
55584,22,0,0,0,0,0,0,0,35,0,8,0,"CHRNA9;cholinergic receptor, nicotinic, alpha 9 (neuronal)",GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane,GO:0070588//calcium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0042472//inner ear morphogenesis;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0005262//calcium channel activity,K04810//Neuroactive ligand-receptor interaction
55585,0,0,0,25,93,0,0,57,6,0,0,0,UBE2Q1;ubiquitin-conjugating enzyme E2Q family member 1,-,GO:0016567//protein ubiquitination;GO:0007566//embryo implantation;GO:0007617//mating behavior;GO:0009566//fertilization;GO:0001967//suckling behavior;GO:0061458//reproductive system development;GO:0070459//prolactin secretion,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding;GO:0005515//protein binding,K10582//Ubiquitin mediated proteolysis
55586,0,0,0,0,0,36,0,0,21,0,1,0,MIOX;myo-inositol oxygenase,GO:0005737//cytoplasm;GO:0016234//inclusion body;GO:0070062//extracellular vesicular exosome,GO:0019310//inositol catabolic process;GO:0055114//oxidation-reduction process,"GO:0008199//ferric iron binding;GO:0004033//aldo-keto reductase (NADP) activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H;GO:0050661//NADP binding;GO:0050113//inositol oxygenase activity",K00469//Inositol phosphate metabolism;Ascorbate and aldarate metabolism
55588,0,116,0,9,29,0,0,0,1,0,0,0,MED29;mediator complex subunit 29,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016592//mediator complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,-
55589,20,15,0,6,29,32,17,0,25,6,1,0,BMP2K;BMP2 inducible kinase,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006468//protein phosphorylation;GO:0030500//regulation of bone mineralization;GO:0050790//regulation of catalytic activity,GO:0004674//protein serine/threonine kinase activity;GO:0019208//phosphatase regulator activity;GO:0005524//ATP binding,K08854//Transcriptional misregulation in cancer
55591,0,38,0,15,26,11,25,60,35,97,1,0,"VEZT;vezatin, adherens junctions transmembrane protein",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0002142//stereocilia ankle link complex;GO:0005634//nucleus;GO:0005912//adherens junction;GO:0005730//nucleolus;GO:0001669//acrosomal vesicle,GO:0043009//chordate embryonic development;GO:0016337//single organismal cell-cell adhesion,GO:0017022//myosin binding,-
55592,0,0,0,0,0,0,2,0,53,0,0,0,GOLGA2P5;golgin A2 pseudogene 5,GO:0005794//Golgi apparatus,-,-,-
55593,0,0,28,17,57,0,0,0,2,0,56,0,OTUD5;OTU deubiquitinase 5,GO:0005829//cytosol,GO:0032496//response to lipopolysaccharide;GO:0070536//protein K63-linked deubiquitination;GO:0045087//innate immune response;GO:0071108//protein K48-linked deubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0006508//proteolysis,GO:0004843//ubiquitin-specific protease activity,K12655//RIG-I-like receptor signaling pathway
55596,0,35,1,0,13,15,0,52,12,0,12,0,"ZCCHC8;zinc finger, CCHC domain containing 8",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus,"GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
55599,0,0,0,0,0,0,0,0,1,0,0,0,"RNPC3;RNA-binding region (RNP1, RRM) containing 3",GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0003723//RNA binding;GO:0000166//nucleotide binding,-
55600,0,0,0,0,0,16,8,0,0,0,18,0,ITLN1;intelectin 1 (galactofuranose binding),GO:0031225//anchored component of membrane;GO:0043235//receptor complex;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane;GO:0045121//membrane raft,GO:0009624//response to nematode;GO:0046326//positive regulation of glucose import;GO:0001934//positive regulation of protein phosphorylation,GO:0030246//carbohydrate binding,-
55601,0,32,0,15,42,48,82,64,49,118,0,0,DDX60;DEAD (Asp-Glu-Ala-Asp) box polypeptide 60,GO:0045111//intermediate filament cytoskeleton;GO:0005737//cytoplasm,GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:1900246//positive regulation of RIG-I signaling pathway;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:0009615//response to virus;GO:0008152//metabolic process,GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0003690//double-stranded DNA binding,K12599//RNA degradation;K01529//Purine metabolism
55602,0,0,0,0,2,0,0,40,0,0,0,0,CDKN2AIP;CDKN2A interacting protein,GO:0005730//nucleolus;GO:0001652//granular component;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0031647//regulation of protein stability;GO:0009967//positive regulation of signal transduction;GO:0030308//negative regulation of cell growth,GO:0003723//RNA binding;GO:0002039//p53 binding;GO:0005515//protein binding,-
55603,87,40,0,11,27,0,0,0,6,1,0,0,"FAM46A;family with sequence similarity 46, member A",-,GO:0030193//regulation of blood coagulation;GO:0010468//regulation of gene expression,GO:0044822//poly(A) RNA binding,-
55604,130,24,0,27,66,35,44,0,36,213,8,1,LRRC16A;leucine rich repeat containing 16A,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030027//lamellipodium,GO:2000813//negative regulation of barbed-end actin filament capping;GO:0051638//barbed-end actin filament uncapping;GO:0046415//urate metabolic process;GO:0007596//blood coagulation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0007015//actin filament organization;GO:0030335//positive regulation of cell migration;GO:0030032//lamellipodium assembly;GO:0016477//cell migration;GO:0051496//positive regulation of stress fiber assembly;GO:0030838//positive regulation of actin filament polymerization;GO:1902745//positive regulation of lamellipodium organization;GO:0031529//ruffle organization,GO:0032403//protein complex binding,K08727//Pertussis;Shigellosis;NOD-like receptor signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;K11147//Retinol metabolism;Peroxisome;Metabolic pathways
55605,24,33,0,39,201,0,22,62,69,0,10,0,KIF21A;kinesin family member 21A,GO:0005871//kinesin complex;GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0005515//protein binding,-
55607,0,0,0,65,31,73,15,43,72,114,2,0,"PPP1R9A;protein phosphatase 1, regulatory subunit 9A",GO:0030426//growth cone;GO:0030864//cortical actin cytoskeleton;GO:0043197//dendritic spine;GO:0045202//synapse;GO:0030054//cell junction;GO:0030175//filopodium,GO:0007015//actin filament organization;GO:0031175//neuron projection development;GO:0019722//calcium-mediated signaling,GO:0005515//protein binding;GO:0003779//actin binding,K06095//Tight junction
55608,0,0,0,0,22,0,39,5,27,0,0,25,ANKRD10;ankyrin repeat domain 10,-,-,-,-
55609,0,0,0,0,48,11,21,0,6,0,1,0,ZNF280C;zinc finger protein 280C,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
55610,0,0,0,16,41,0,0,0,72,0,0,0,CCDC132;coiled-coil domain containing 132,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,-,-,-
55611,0,0,0,0,41,31,0,0,10,0,0,0,"OTUB1;OTU deubiquitinase, ubiquitin aldehyde binding 1",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0002376//immune system process;GO:0006508//proteolysis;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:2000780//negative regulation of double-strand break repair;GO:0071108//protein K48-linked deubiquitination;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination,GO:0008242//omega peptidase activity;GO:0043130//ubiquitin binding;GO:0031625//ubiquitin protein ligase binding;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0019784//NEDD8-specific protease activity,-
55612,0,0,0,0,0,1,8,0,57,0,7,53,FERMT1;fermitin family member 1,GO:0030054//cell junction;GO:0005925//focal adhesion;GO:0031941//filamentous actin;GO:0032587//ruffle membrane;GO:0005829//cytosol,GO:0007155//cell adhesion;GO:0090162//establishment of epithelial cell polarity;GO:0051546//keratinocyte migration;GO:0043616//keratinocyte proliferation,-,K06271//HTLV-I infection;Focal adhesion
55613,88,0,0,0,0,31,0,0,33,0,0,0,MTMR8;myotubularin related protein 8,GO:0005635//nuclear envelope,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity,K01112//Fructose and mannose metabolism
55614,64,0,1,7,6,8,0,0,25,163,3,0,KIF16B;kinesin family member 16B,GO:0031901//early endosome membrane;GO:0005871//kinesin complex;GO:0005769//early endosome;GO:0005768//endosome;GO:0005874//microtubule,GO:0032801//receptor catabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007018//microtubule-based movement;GO:0006200//ATP catabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045022//early endosome to late endosome transport;GO:0001704//formation of primary germ layer;GO:0006895//Golgi to endosome transport;GO:0001919//regulation of receptor recycling;GO:0007492//endoderm development,"GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0017137//Rab GTPase binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding",-
55615,0,0,0,0,0,18,0,0,36,230,2,2,PRR5;proline rich 5 (renal),GO:0031932//TORC2 complex,GO:0001934//positive regulation of protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007049//cell cycle,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
55616,98,1,0,2,36,43,25,0,35,0,14,0,"ASAP3;ArfGAP with SH3 domain, ankyrin repeat and PH domain 3",GO:0005925//focal adhesion;GO:0001726//ruffle;GO:0005737//cytoplasm,GO:0032850//positive regulation of ARF GTPase activity;GO:0051492//regulation of stress fiber assembly;GO:0016477//cell migration,GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K12488//Fc gamma R-mediated phagocytosis;Endocytosis
55617,0,15,0,0,15,0,33,0,23,0,9,0,"TASP1;taspase, threonine aspartase, 1",-,"GO:0006508//proteolysis;GO:0045893//positive regulation of transcription, DNA-templated",GO:0004298//threonine-type endopeptidase activity,-
55619,0,0,0,0,0,23,82,0,80,0,5,5,DOCK10;dedicator of cytokinesis 10,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0030334//regulation of cell migration;GO:0007264//small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity,GO:0017048//Rho GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
5562,0,65,42,68,395,31,37,0,8,0,0,0,"PRKAA1;protein kinase, AMP-activated, alpha 1 catalytic subunit",GO:0031588//AMP-activated protein kinase complex;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005622//intracellular;GO:0005829//cytosol,"GO:0042752//regulation of circadian rhythm;GO:0006695//cholesterol biosynthetic process;GO:0006914//autophagy;GO:0008286//insulin receptor signaling pathway;GO:0035404//histone-serine phosphorylation;GO:0016055//Wnt signaling pathway;GO:2001274//negative regulation of glucose import in response to insulin stimulus;GO:0007050//cell cycle arrest;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0009411//response to UV;GO:0009631//cold acclimation;GO:0050995//negative regulation of lipid catabolic process;GO:0045821//positive regulation of glycolytic process;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0014823//response to activity;GO:0060627//regulation of vesicle-mediated transport;GO:0042593//glucose homeostasis;GO:0008610//lipid biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0046318//negative regulation of glucosylceramide biosynthetic process;GO:0031669//cellular response to nutrient levels;GO:0032007//negative regulation of TOR signaling;GO:0001666//response to hypoxia;GO:0055089//fatty acid homeostasis;GO:0051291//protein heterooligomerization;GO:0006468//protein phosphorylation;GO:2000505//regulation of energy homeostasis;GO:0006633//fatty acid biosynthetic process;GO:0048511//rhythmic process;GO:0031000//response to caffeine;GO:0006006//glucose metabolic process;GO:0007165//signal transduction;GO:0042149//cellular response to glucose starvation;GO:0070301//cellular response to hydrogen peroxide;GO:0010332//response to gamma radiation;GO:0000187//activation of MAPK activity;GO:0071361//cellular response to ethanol;GO:0019395//fatty acid oxidation;GO:0071456//cellular response to hypoxia;GO:0010508//positive regulation of autophagy;GO:0006355//regulation of transcription, DNA-templated",GO:0019900//kinase binding;GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0035174//histone serine kinase activity;GO:0005524//ATP binding;GO:0004691//cAMP-dependent protein kinase activity;GO:0004672//protein kinase activity;GO:0050321//tau-protein kinase activity,K07198//Adipocytokine signaling pathway;Regulation of autophagy;Hypertrophic cardiomyopathy (HCM);Insulin signaling pathway;mTOR signaling pathway
55620,0,1,0,0,33,3,3,0,39,0,3,0,STAP2;signal transducing adaptor family member 2,GO:0005737//cytoplasm;GO:0005886//plasma membrane,-,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K06641//HTLV-I infection;Cell cycle - yeast;Cell cycle;p53 signaling pathway
55621,61,0,0,0,0,0,1,36,18,0,2,0,TRMT1;tRNA methyltransferase 1 homolog (S. cerevisiae),-,GO:0030488//tRNA methylation,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0000049//tRNA binding;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity,-
55622,0,0,0,0,11,0,0,0,29,90,16,0,TTC27;tetratricopeptide repeat domain 27,-,-,-,K03350//Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;HTLV-I infection;Meiosis - yeast;Oocyte meiosis
55623,0,29,0,57,206,0,1,0,11,0,0,0,THUMPD1;THUMP domain containing 1,-,-,GO:0044822//poly(A) RNA binding,-
55624,0,31,0,17,46,0,0,111,42,0,61,0,"POMGNT1;protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006493//protein O-linked glycosylation,"GO:0047223//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity",K09666//Other types of O-glycan biosynthesis
55625,0,0,0,1,0,0,8,0,57,0,1,0,"ZDHHC7;zinc finger, DHHC-type containing 7",GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0018230//peptidyl-L-cysteine S-palmitoylation;GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
55626,0,0,0,0,0,0,0,0,0,0,7,0,AMBRA1;autophagy/beclin-1 regulator 1,GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0005776//autophagic vacuole;GO:0045335//phagocytic vesicle,GO:0008285//negative regulation of cell proliferation;GO:0030154//cell differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0006914//autophagy;GO:0021915//neural tube development,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
55627,4,1258,593,671,981,12,204,5487,911,474,1919,40,"SMPD4;sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)",GO:0005789//endoplasmic reticulum membrane;GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0071356//cellular response to tumor necrosis factor;GO:0006687//glycosphingolipid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0044281//small molecule metabolic process;GO:0046513//ceramide biosynthetic process;GO:0006685//sphingomyelin catabolic process;GO:0006665//sphingolipid metabolic process,GO:0004767//sphingomyelin phosphodiesterase activity;GO:0050290//sphingomyelin phosphodiesterase D activity;GO:0046872//metal ion binding,K12353//Sphingolipid metabolism;Metabolic pathways
55628,12,0,0,14,13,36,3,68,27,58,0,0,ZNF407;zinc finger protein 407,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
55629,0,0,1,1,33,0,0,0,0,0,0,0,PNRC2;proline-rich nuclear receptor coactivator 2,GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body,"GO:0006351//transcription, DNA-templated;GO:0031087//deadenylation-independent decapping of nuclear-transcribed mRNA;GO:0006355//regulation of transcription, DNA-templated;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0005515//protein binding,-
5563,0,0,1,46,85,15,2,0,67,0,0,0,"PRKAA2;protein kinase, AMP-activated, alpha 2 catalytic subunit",GO:0005829//cytosol;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010508//positive regulation of autophagy;GO:0044281//small molecule metabolic process;GO:0031669//cellular response to nutrient levels;GO:0008610//lipid biosynthetic process;GO:0042593//glucose homeostasis;GO:0044255//cellular lipid metabolic process;GO:0006853//carnitine shuttle;GO:0045821//positive regulation of glycolytic process;GO:0042304//regulation of fatty acid biosynthetic process;GO:0043066//negative regulation of apoptotic process;GO:0042149//cellular response to glucose starvation;GO:0006351//transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction;GO:0007050//cell cycle arrest;GO:0006633//fatty acid biosynthetic process;GO:0035404//histone-serine phosphorylation;GO:2000505//regulation of energy homeostasis;GO:0048511//rhythmic process;GO:0006950//response to stress;GO:0008286//insulin receptor signaling pathway;GO:0061024//membrane organization;GO:0006468//protein phosphorylation;GO:0006695//cholesterol biosynthetic process;GO:0042752//regulation of circadian rhythm;GO:0032007//negative regulation of TOR signaling;GO:0055089//fatty acid homeostasis;GO:0006112//energy reserve metabolic process;GO:0006914//autophagy",GO:0047322//[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity;GO:0004679//AMP-activated protein kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0050405//[acetyl-CoA carboxylase] kinase activity;GO:0005524//ATP binding;GO:0035174//histone serine kinase activity;GO:0003682//chromatin binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity,K07198//Insulin signaling pathway;mTOR signaling pathway;Adipocytokine signaling pathway;Regulation of autophagy;Hypertrophic cardiomyopathy (HCM)
55630,5,0,22,4,0,1,14,0,8,0,31,0,"SLC39A4;solute carrier family 39 (zinc transporter), member 4",GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0055038//recycling endosome membrane;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006882//cellular zinc ion homeostasis;GO:0071577//zinc ion transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity,K14710//Mineral absorption
55631,0,0,0,4,22,6,57,0,40,0,0,0,LRRC40;leucine rich repeat containing 40,GO:0016020//membrane,-,-,K12796//NOD-like receptor signaling pathway
55632,0,34,0,0,0,0,28,0,6,89,0,0,G2E3;G2/M-phase specific E3 ubiquitin protein ligase,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0001824//blastocyst development;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0000209//protein polyubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,K09188//Lysine degradation;K11421//Lysine degradation;K09186//Lysine degradation;Transcriptional misregulation in cancer
55633,0,0,1,7,27,0,0,0,31,23,9,0,"TBC1D22B;TBC1 domain family, member 22B",-,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
55634,0,0,0,6,0,0,0,0,9,0,0,0,KRBOX4;KRAB box domain containing 4,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,-
55635,0,111,0,0,43,1,1,126,22,101,0,0,DEPDC1;DEP domain containing 1,GO:0017053//transcriptional repressor complex;GO:0005634//nucleus,"GO:0043547//positive regulation of GTPase activity;GO:0035556//intracellular signal transduction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0005096//GTPase activator activity,-
55636,42,1,1,34,67,54,0,83,84,92,15,0,CHD7;chromodomain helicase DNA binding protein 7,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0050767//regulation of neurogenesis;GO:0048806//genitalia development;GO:0021772//olfactory bulb development;GO:0007512//adult heart development;GO:0008015//blood circulation;GO:0021553//olfactory nerve development;GO:0007628//adult walking behavior;GO:0043584//nose development;GO:0006355//regulation of transcription, DNA-templated;GO:0048752//semicircular canal morphogenesis;GO:0030217//T cell differentiation;GO:0006364//rRNA processing;GO:0001701//in utero embryonic development;GO:0007605//sensory perception of sound;GO:0060173//limb development;GO:0060429//epithelium development;GO:0050890//cognition;GO:0001501//skeletal system development;GO:0048844//artery morphogenesis;GO:0003007//heart morphogenesis;GO:0016568//chromatin modification;GO:0030540//female genitalia development;GO:0040018//positive regulation of multicellular organism growth;GO:0060041//retina development in camera-type eye;GO:0060324//face development;GO:0042048//olfactory behavior;GO:0060021//palate development;GO:0007417//central nervous system development;GO:0060123//regulation of growth hormone secretion;GO:0006351//transcription, DNA-templated;GO:0035116//embryonic hindlimb morphogenesis;GO:0042472//inner ear morphogenesis;GO:0021545//cranial nerve development",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0003682//chromatin binding;GO:0005524//ATP binding,-
55638,0,1,0,0,25,0,0,0,17,0,0,0,SYBU;syntabulin (syntaxin-interacting),GO:0005856//cytoskeleton;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0097433//dense body,GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0005515//protein binding;GO:0017075//syntaxin-1 binding;GO:0008017//microtubule binding;GO:0019894//kinesin binding,-
5564,0,0,0,1,1,0,21,0,11,0,0,0,"PRKAB1;protein kinase, AMP-activated, beta 1 non-catalytic subunit",GO:0005829//cytosol;GO:0005634//nucleus;GO:0031588//AMP-activated protein kinase complex,GO:0006633//fatty acid biosynthetic process;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0007050//cell cycle arrest;GO:0061024//membrane organization;GO:0010628//positive regulation of gene expression;GO:0006468//protein phosphorylation;GO:0051291//protein heterooligomerization;GO:0008286//insulin receptor signaling pathway,GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0005515//protein binding,K07199//Insulin signaling pathway;Adipocytokine signaling pathway;Hypertrophic cardiomyopathy (HCM)
55640,9,0,14,0,0,2,3,0,1,103,24,0,"FLVCR2;feline leukemia virus subgroup C cellular receptor family, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0015886//heme transport;GO:0055085//transmembrane transport,GO:0020037//heme binding;GO:0015232//heme transporter activity,-
55643,0,1,0,9,19,0,0,0,18,0,29,0,BTBD2;BTB (POZ) domain containing 2,GO:0000932//cytoplasmic mRNA processing body,-,GO:0005515//protein binding,-
55644,42,3,0,0,0,0,4,0,6,0,0,0,OSGEP;O-sialoglycoprotein endopeptidase,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0070526//threonylcarbamoyladenosine biosynthetic process,"GO:0046872//metal ion binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups",-
55646,21,16,0,0,0,0,0,0,40,0,0,0,LYAR;Ly1 antibody reactive,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
55647,0,0,0,4,20,7,0,0,0,0,0,0,"RAB20;RAB20, member RAS oncogene family",GO:0030670//phagocytic vesicle membrane;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus;GO:0043231//intracellular membrane-bounded organelle,GO:0090385//phagosome-lysosome fusion;GO:0015031//protein transport;GO:0090383//phagosome acidification;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
5565,0,0,0,1,47,0,26,0,0,0,0,0,"PRKAB2;protein kinase, AMP-activated, beta 2 non-catalytic subunit",GO:0031588//AMP-activated protein kinase complex;GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0007050//cell cycle arrest;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0006468//protein phosphorylation;GO:0061024//membrane organization;GO:0042304//regulation of fatty acid biosynthetic process;GO:0008286//insulin receptor signaling pathway;GO:0006853//carnitine shuttle;GO:0006112//energy reserve metabolic process,GO:0004679//AMP-activated protein kinase activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K07199//Adipocytokine signaling pathway;Hypertrophic cardiomyopathy (HCM);Insulin signaling pathway
55650,0,0,0,0,1,0,11,0,25,0,1,0,"PIGV;phosphatidylinositol glycan anchor biosynthesis, class V",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0097502//mannosylation;GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process,GO:0000030//mannosyltransferase activity,K07542//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
55651,0,88,94,91,141,28,59,1,0,0,84,0,NHP2;NHP2 ribonucleoprotein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0015030//Cajal body;GO:0005730//nucleolus,GO:0031118//rRNA pseudouridine synthesis,GO:0044822//poly(A) RNA binding;GO:0030515//snoRNA binding,K11129//Ribosome biogenesis in eukaryotes
55652,0,0,0,0,0,0,0,0,8,0,0,52,"SLC48A1;solute carrier family 48 (heme transporter), member 1",GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0005765//lysosomal membrane,GO:0015886//heme transport,GO:0015232//heme transporter activity,-
55654,86,0,0,0,0,25,20,0,79,29,13,0,TMEM127;transmembrane protein 127,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0032007//negative regulation of TOR signaling;GO:0008285//negative regulation of cell proliferation,-,K11447//Transcriptional misregulation in cancer;K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Biotin metabolism;Arginine and proline metabolism;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
55655,0,0,0,2,8,0,0,3,30,0,0,451,"NLRP2;NLR family, pyrin domain containing 2",GO:0005737//cytoplasm,GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0032090//Pyrin domain binding,K12800//NOD-like receptor signaling pathway;Influenza A;Pertussis
55656,0,0,0,7,21,0,0,0,31,142,0,0,INTS8;integrator complex subunit 8,GO:0032039//integrator complex,GO:0016180//snRNA processing,GO:0005515//protein binding,-
55657,0,0,1,0,35,0,14,159,38,66,45,0,ZNF692;zinc finger protein 692,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
55658,0,0,0,1,0,0,0,0,17,0,12,0,RNF126;ring finger protein 126,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042147//retrograde transport, endosome to Golgi;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0042127//regulation of cell proliferation;GO:0032880//regulation of protein localization;GO:0070936//protein K48-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0006513//protein monoubiquitination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway",GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity,-
55659,0,0,45,0,2,0,0,20,11,0,0,0,ZNF416;zinc finger protein 416,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
5566,0,31,0,0,8,7,0,60,31,0,0,0,"PRKACA;protein kinase, cAMP-dependent, catalytic, alpha",GO:0005952//cAMP-dependent protein kinase complex;GO:0005813//centrosome;GO:0097225//sperm midpiece;GO:0031594//neuromuscular junction;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0097546//ciliary base;GO:0005634//nucleus;GO:0034704//calcium channel complex;GO:0031588//AMP-activated protein kinase complex;GO:0031514//motile cilium;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:2000810//regulation of tight junction assembly;GO:0035556//intracellular signal transduction;GO:0051480//cytosolic calcium ion homeostasis;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0071872//cellular response to epinephrine stimulus;GO:0006094//gluconeogenesis;GO:0048240//sperm capacitation;GO:0055117//regulation of cardiac muscle contraction;GO:0071158//positive regulation of cell cycle arrest;GO:0045087//innate immune response;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0018107//peptidyl-threonine phosphorylation;GO:0071333//cellular response to glucose stimulus;GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process;GO:0001843//neural tube closure;GO:0070613//regulation of protein processing;GO:0034199//activation of protein kinase A activity;GO:0050804//regulation of synaptic transmission;GO:0046827//positive regulation of protein export from nucleus;GO:0061136//regulation of proteasomal protein catabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007202//activation of phospholipase C activity;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0019433//triglyceride catabolic process;GO:0055085//transmembrane transport;GO:0050796//regulation of insulin secretion;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001707//mesoderm formation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0000086//G2/M transition of mitotic cell cycle;GO:0045667//regulation of osteoblast differentiation;GO:0000278//mitotic cell cycle;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0002027//regulation of heart rate;GO:0006468//protein phosphorylation;GO:0006006//glucose metabolic process;GO:0046777//protein autophosphorylation;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0006833//water transport;GO:0043393//regulation of protein binding;GO:0005975//carbohydrate metabolic process,GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding;GO:0004691//cAMP-dependent protein kinase activity,K04345//Taste transduction;Glutamatergic synapse;Amphetamine addiction;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Wnt signaling pathway;Amoebiasis;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Long-term potentiation;Melanogenesis;Vibrio cholerae infection;GABAergic synapse;Cholinergic synapse;Dilated cardiomyopathy;Salivary secretion;Apoptosis;Hedgehog signaling pathway;MAPK signaling pathway;Oocyte meiosis;Morphine addiction;Epstein-Barr virus infection;GnRH signaling pathway;Chemokine signaling pathway;Gap junction;Cocaine addiction;Dopaminergic synapse;Meiosis - yeast;Serotonergic synapse;Alcoholism;Prion diseases;Gastric acid secretion;Bile secretion;HTLV-I infection;Olfactory transduction;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption
55660,0,0,0,27,123,10,19,1,50,0,0,0,PRPF40A;PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae),GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix,GO:0008380//RNA splicing;GO:0007010//cytoskeleton organization;GO:0006397//mRNA processing;GO:0008360//regulation of cell shape;GO:0016477//cell migration;GO:0051301//cell division;GO:0007049//cell cycle;GO:0032465//regulation of cytokinesis,GO:0070064//proline-rich region binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12821//Spliceosome
55661,180,0,0,6,45,0,0,0,19,0,0,0,DDX27;DEAD (Asp-Glu-Ala-Asp) box polypeptide 27,GO:0005634//nucleus,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity,-
55662,0,28,2,34,68,0,3,0,26,0,5,0,"HIF1AN;hypoxia inducible factor 1, alpha subunit inhibitor",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0055114//oxidation-reduction process;GO:0042265//peptidyl-asparagine hydroxylation;GO:0006351//transcription, DNA-templated;GO:0036138//peptidyl-histidine hydroxylation;GO:0042264//peptidyl-aspartic acid hydroxylation;GO:0045746//negative regulation of Notch signaling pathway;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:2001214//positive regulation of vasculogenesis;GO:0045663//positive regulation of myoblast differentiation;GO:0071456//cellular response to hypoxia;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia","GO:0019826//oxygen sensor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0071532//ankyrin repeat binding;GO:0031406//carboxylic acid binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0048037//cofactor binding;GO:0036140//peptidyl-asparagine 3-dioxygenase activity;GO:0036139//peptidyl-histidine dioxygenase activity;GO:0005112//Notch binding;GO:0051059//NF-kappaB binding",-
55663,0,0,0,8,45,0,0,124,13,1,36,552,ZNF446;zinc finger protein 446,GO:0005615//extracellular space;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
55664,0,38,0,18,87,0,12,0,0,0,0,0,CDC37L1;cell division cycle 37-like 1,GO:0005737//cytoplasm,-,-,-
55665,110,0,0,0,15,0,9,112,0,0,2,0,URGCP;upregulator of cell proliferation,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007049//cell cycle,GO:0005525//GTP binding,K12797//NOD-like receptor signaling pathway
55666,25,1,0,33,6,24,42,124,25,0,21,0,NPLOC4;nuclear protein localization 4 homolog (S. cerevisiae),GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0042175//nuclear outer membrane-endoplasmic reticulum membrane network,GO:0061025//membrane fusion;GO:0007030//Golgi organization;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0008270//zinc ion binding,K14015//Protein processing in endoplasmic reticulum
55667,0,91,47,106,271,45,57,1,28,0,7,0,DENND4C;DENN/MADD domain containing 4C,GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030904//retromer complex;GO:0032593//insulin-responsive compartment,GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport;GO:0072659//protein localization to plasma membrane;GO:0032869//cellular response to insulin stimulus,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism
55668,72,1,25,0,55,34,0,0,31,124,0,0,GPATCH2L;G patch domain containing 2-like,-,-,GO:0005515//protein binding,-
55669,112,88,0,8,81,0,17,0,22,0,2,0,MFN1;mitofusin 1,GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0008053//mitochondrial fusion;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
5567,0,54,0,71,107,0,11,0,5,0,1,0,"PRKACB;protein kinase, cAMP-dependent, catalytic, beta",GO:0097546//ciliary base;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005952//cAMP-dependent protein kinase complex;GO:0005813//centrosome;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission;GO:0007596//blood coagulation;GO:0097338//response to clozapine;GO:0006112//energy reserve metabolic process;GO:0006006//glucose metabolic process;GO:0001843//neural tube closure;GO:0070613//regulation of protein processing;GO:0034199//activation of protein kinase A activity;GO:0006833//water transport;GO:0007165//signal transduction;GO:0005975//carbohydrate metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051447//negative regulation of meiotic cell cycle;GO:0007202//activation of phospholipase C activity;GO:0055085//transmembrane transport;GO:0035556//intracellular signal transduction;GO:0019433//triglyceride catabolic process;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0006094//gluconeogenesis;GO:0050796//regulation of insulin secretion;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus,GO:0005524//ATP binding;GO:0004691//cAMP-dependent protein kinase activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K04345//Epstein-Barr virus infection;Morphine addiction;Oocyte meiosis;MAPK signaling pathway;Hedgehog signaling pathway;Apoptosis;Alcoholism;Serotonergic synapse;Meiosis - yeast;Cocaine addiction;Dopaminergic synapse;Gap junction;Chemokine signaling pathway;GnRH signaling pathway;Bile secretion;Gastric acid secretion;Prion diseases;Endocrine and other factor-regulated calcium reabsorption;Olfactory transduction;Retrograde endocannabinoid signaling;Calcium signaling pathway;HTLV-I infection;Amoebiasis;Wnt signaling pathway;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Taste transduction;Glutamatergic synapse;Amphetamine addiction;Long-term potentiation;Progesterone-mediated oocyte maturation;Insulin signaling pathway;Melanogenesis;Vibrio cholerae infection;Salivary secretion;Dilated cardiomyopathy;Cholinergic synapse;GABAergic synapse
55670,0,28,0,0,61,17,0,0,9,0,15,0,PEX26;peroxisomal biogenesis factor 26,GO:0005779//integral component of peroxisomal membrane;GO:0005777//peroxisome,GO:0045046//protein import into peroxisome membrane;GO:0016558//protein import into peroxisome matrix,GO:0005515//protein binding;GO:0051117//ATPase binding;GO:0032403//protein complex binding;GO:0008022//protein C-terminus binding,K13340//Peroxisome
55671,0,3,1,28,29,16,0,0,52,0,6,0,"SMEK1;SMEK homolog 1, suppressor of mek1 (Dictyostelium)",GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030289//protein phosphatase 4 complex,GO:0006470//protein dephosphorylation;GO:0045722//positive regulation of gluconeogenesis,-,-
55672,137,14,0,41,30,27,84,3,146,100,20,0,"NBPF1;neuroblastoma breakpoint family, member 1",GO:0005737//cytoplasm,-,-,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K12478//Endocytosis;Phagosome;Tuberculosis
55676,0,0,0,0,6,38,18,0,48,0,0,0,"SLC30A6;solute carrier family 30 (zinc transporter), member 6",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005794//Golgi apparatus,GO:0044267//cellular protein metabolic process;GO:0055085//transmembrane transport;GO:0006895//Golgi to endosome transport;GO:0071577//zinc ion transmembrane transport,GO:0005385//zinc ion transmembrane transporter activity,-
55677,0,0,152,13,25,11,35,238,0,0,56,0,IWS1;IWS1 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0090239//regulation of histone H4 acetylation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0006351//transcription, DNA-templated;GO:2001253//regulation of histone H3-K36 trimethylation;GO:0050684//regulation of mRNA processing;GO:0006355//regulation of transcription, DNA-templated;GO:0010793//regulation of mRNA export from nucleus;GO:0051028//mRNA transport",GO:0005515//protein binding;GO:0003677//DNA binding,-
55679,0,0,0,0,0,0,0,0,37,0,5,0,LIMS2;LIM and senescent cell antigen-like domains 2,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005925//focal adhesion,GO:2000178//negative regulation of neural precursor cell proliferation;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0045216//cell-cell junction organization;GO:2000346//negative regulation of hepatocyte proliferation;GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly,GO:0008270//zinc ion binding,K05760//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway;VEGF signaling pathway;Leukocyte transendothelial migration;Focal adhesion
5568,0,0,0,0,0,0,0,0,14,0,0,0,"PRKACG;protein kinase, cAMP-dependent, catalytic, gamma",GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process;GO:0007283//spermatogenesis;GO:0008584//male gonad development;GO:0006468//protein phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006006//glucose metabolic process;GO:0006833//water transport;GO:0007165//signal transduction;GO:0034199//activation of protein kinase A activity;GO:0050796//regulation of insulin secretion;GO:0006094//gluconeogenesis;GO:0055085//transmembrane transport;GO:0019433//triglyceride catabolic process;GO:0035556//intracellular signal transduction;GO:0007202//activation of phospholipase C activity;GO:0045087//innate immune response;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0004691//cAMP-dependent protein kinase activity,K04345//Cholinergic synapse;GABAergic synapse;Salivary secretion;Dilated cardiomyopathy;Melanogenesis;Vibrio cholerae infection;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Long-term potentiation;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Wnt signaling pathway;Amphetamine addiction;Glutamatergic synapse;Taste transduction;Amoebiasis;HTLV-I infection;Olfactory transduction;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Prion diseases;Bile secretion;Gastric acid secretion;Meiosis - yeast;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Cocaine addiction;Dopaminergic synapse;Serotonergic synapse;Alcoholism;Oocyte meiosis;Morphine addiction;Hedgehog signaling pathway;Apoptosis;MAPK signaling pathway;Epstein-Barr virus infection
55680,193,30,172,128,310,20,1,46,4,0,65,0,RUFY2;RUN and FYVE domain containing 2,GO:0005634//nucleus,-,GO:0046872//metal ion binding,K12482//Endocytosis
55681,49,36,0,18,126,0,45,0,36,1,0,0,SCYL2;SCY1-like 2 (S. cerevisiae),GO:0048471//perinuclear region of cytoplasm;GO:0010008//endosome membrane;GO:0030136//clathrin-coated vesicle;GO:0005794//Golgi apparatus,GO:0006468//protein phosphorylation;GO:0002092//positive regulation of receptor internalization;GO:2000370//positive regulation of clathrin-mediated endocytosis;GO:0008333//endosome to lysosome transport;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway,GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005102//receptor binding;GO:0005524//ATP binding,-
55683,26,22,0,12,2,33,0,2,29,0,4,0,KANSL3;KAT8 regulatory NSL complex subunit 3,GO:0043231//intracellular membrane-bounded organelle;GO:0000123//histone acetyltransferase complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0043984//histone H4-K16 acetylation;GO:0006325//chromatin organization;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation,GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0043996//histone acetyltransferase activity (H4-K8 specific),-
55684,0,90,73,26,41,0,51,1,113,0,44,0,"RABL6;RAB, member RAS oncogene family-like 6",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding,K07874//Legionellosis;K07897//Amoebiasis;Tuberculosis;Phagosome;Endocytosis;Salmonella infection
55686,0,0,0,0,11,0,0,0,34,0,12,0,MREG;melanoregulin,GO:0016324//apical plasma membrane,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
55687,0,0,0,0,0,0,0,0,11,0,0,0,TRMU;tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase,GO:0005739//mitochondrion,GO:0008033//tRNA processing,GO:0016783//sulfurtransferase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding,K00566//Galactose metabolism;Flagellar assembly;Ribosome;Bacterial chemotaxis;Sulfur relay system
55689,0,0,0,8,54,17,0,111,39,5,0,0,YEATS2;YEATS domain containing 2,GO:0072686//mitotic spindle;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,"GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0017025//TBP-class protein binding,-
5569,65,30,0,19,35,0,54,0,0,0,7,304,"PKIA;protein kinase (cAMP-dependent, catalytic) inhibitor alpha",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042308//negative regulation of protein import into nucleus;GO:2000480//negative regulation of cAMP-dependent protein kinase activity,GO:0034236//protein kinase A catalytic subunit binding;GO:0005515//protein binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity,K15985//Alcoholism
55690,0,25,0,3,58,9,37,58,46,0,31,0,PACS1;phosphofurin acidic cluster sorting protein 1,GO:0005829//cytosol;GO:0030137//COPI-coated vesicle,GO:0050690//regulation of defense response to virus by virus;GO:0016032//viral process;GO:0072661//protein targeting to plasma membrane;GO:0000042//protein targeting to Golgi,GO:0005515//protein binding;GO:0044325//ion channel binding,-
55691,137,0,71,0,73,3,67,1,37,0,10,320,FRMD4A;FERM domain containing 4A,GO:0005923//tight junction;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0090162//establishment of epithelial cell polarity,"GO:0030674//protein binding, bridging",K08007//Gastric acid secretion;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;K12817//Spliceosome;K05763//Leukocyte transendothelial migration;Measles;Regulation of actin cytoskeleton;K05762//Regulation of actin cytoskeleton
55692,1,28,0,0,0,0,3,0,7,0,0,0,LUC7L;LUC7-like (S. cerevisiae),GO:0005685//U1 snRNP,GO:0006376//mRNA splice site selection;GO:0045843//negative regulation of striated muscle tissue development,GO:0003729//mRNA binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0050733//RS domain binding,-
55693,0,1,0,0,0,21,0,0,48,54,0,0,KDM4D;lysine (K)-specific demethylase 4D,GO:0072562//blood microparticle;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0055114//oxidation-reduction process;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0051213//dioxygenase activity;GO:0046872//metal ion binding,-
55695,45,10,0,0,8,0,0,5,8,0,25,0,"NSUN5;NOP2/Sun domain family, member 5",GO:0005730//nucleolus;GO:0005634//nucleus,GO:0032259//methylation,GO:0044822//poly(A) RNA binding;GO:0008168//methyltransferase activity,-
55696,0,0,0,0,24,24,0,0,8,0,0,0,RBM22;RNA binding motif protein 22,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus,"GO:0090316//positive regulation of intracellular protein transport;GO:0000060//protein import into nucleus, translocation;GO:0000398//mRNA splicing, via spliceosome;GO:0045292//mRNA cis splicing, via spliceosome;GO:0035690//cellular response to drug;GO:0033120//positive regulation of RNA splicing",GO:0048306//calcium-dependent protein binding;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0036002//pre-mRNA binding;GO:0017069//snRNA binding,K12872//Spliceosome
55697,33,8,0,0,0,1,61,113,33,0,0,0,VAC14;Vac14 homolog (S. cerevisiae),GO:0000139//Golgi membrane;GO:0031901//early endosome membrane;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0031902//late endosome membrane;GO:0070772//PAS complex,GO:0006661//phosphatidylinositol biosynthetic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0043550//regulation of lipid kinase activity;GO:0006644//phospholipid metabolic process;GO:0016032//viral process,GO:0005515//protein binding;GO:0004872//receptor activity,K15305//HTLV-I infection
55698,0,0,0,0,1,24,0,0,30,0,0,0,RADIL;Ras association and DIL domains,GO:0005874//microtubule,GO:0007275//multicellular organismal development;GO:0007165//signal transduction;GO:0034446//substrate adhesion-dependent cell spreading,-,K05702//Leukocyte transendothelial migration;Adherens junction;Tight junction;K05631//Tight junction
55699,0,0,0,1,57,0,2,0,80,0,4,0,"IARS2;isoleucyl-tRNA synthetase 2, mitochondrial",GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,GO:0006428//isoleucyl-tRNA aminoacylation;GO:0006450//regulation of translational fidelity;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0002161//aminoacyl-tRNA editing activity;GO:0004822//isoleucine-tRNA ligase activity;GO:0005524//ATP binding,K01870//Aminoacyl-tRNA biosynthesis;Flagellar assembly
5570,0,0,37,5,0,22,0,34,0,26,0,0,"PKIB;protein kinase (cAMP-dependent, catalytic) inhibitor beta",-,GO:0071901//negative regulation of protein serine/threonine kinase activity,GO:0004862//cAMP-dependent protein kinase inhibitor activity,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism;K15985//Alcoholism
55700,0,1,0,2,12,32,21,48,23,0,2,0,MAP7D1;MAP7 domain containing 1,GO:0005819//spindle;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0000226//microtubule cytoskeleton organization,-,-
55701,0,26,43,0,10,0,26,0,41,0,8,0,ARHGEF40;Rho guanine nucleotide exchange factor (GEF) 40,GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,-
55702,60,0,0,1,0,0,0,1,0,0,12,0,CCDC94;coiled-coil domain containing 94,-,-,-,-
55703,0,0,0,21,26,33,44,38,55,0,0,0,POLR3B;polymerase (RNA) III (DNA directed) polypeptide B,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex,GO:0045089//positive regulation of innate immune response;GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0032481//positive regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0006386//termination of RNA polymerase III transcription,GO:0032549//ribonucleoside binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K03021//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Cytosolic DNA-sensing pathway;Metabolic pathways
55704,0,0,0,8,62,29,32,0,11,0,30,0,CCDC88A;coiled-coil domain containing 88A,GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005829//cytosol,GO:0030032//lamellipodium assembly;GO:0061024//membrane organization;GO:0006260//DNA replication;GO:0032956//regulation of actin cytoskeleton organization;GO:0001932//regulation of protein phosphorylation;GO:0032148//activation of protein kinase B activity;GO:0042127//regulation of cell proliferation;GO:0016477//cell migration;GO:0031929//TOR signaling;GO:0010975//regulation of neuron projection development;GO:0006275//regulation of DNA replication,GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding;GO:0043422//protein kinase B binding,-
55705,197,1,1,2,91,59,81,0,116,0,6,0,IPO9;importin 9,GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006606//protein import into nucleus,GO:0008565//protein transporter activity;GO:0008536//Ran GTPase binding;GO:0042393//histone binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer
55706,0,36,30,0,0,0,53,0,33,0,0,0,NDC1;NDC1 transmembrane nucleoporin,GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0016020//membrane,GO:0031081//nuclear pore distribution;GO:0051028//mRNA transport;GO:0007129//synapsis;GO:0051292//nuclear pore complex assembly;GO:0015031//protein transport;GO:0007283//spermatogenesis,GO:0017056//structural constituent of nuclear pore,K14315//RNA transport
55707,97,0,0,1,21,0,0,0,58,0,0,0,NECAP2;NECAP endocytosis associated 2,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0030125//clathrin vesicle coat;GO:0005905//coated pit,GO:0006897//endocytosis;GO:0015031//protein transport,-,-
55709,0,141,27,120,152,0,0,18,16,0,94,0,KBTBD4;kelch repeat and BTB (POZ) domain containing 4,-,-,-,-
5571,0,0,1,24,66,43,0,61,41,0,10,0,"PRKAG1;protein kinase, AMP-activated, gamma 1 non-catalytic subunit",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0031588//AMP-activated protein kinase complex;GO:0005634//nucleus,GO:0010628//positive regulation of gene expression;GO:0061024//membrane organization;GO:0006468//protein phosphorylation;GO:0051291//protein heterooligomerization;GO:0007283//spermatogenesis;GO:0008286//insulin receptor signaling pathway;GO:0007165//signal transduction;GO:0007050//cell cycle arrest;GO:0045860//positive regulation of protein kinase activity;GO:0006110//regulation of glycolytic process;GO:0006633//fatty acid biosynthetic process,GO:0004679//AMP-activated protein kinase activity;GO:0016208//AMP binding;GO:0043531//ADP binding;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0004691//cAMP-dependent protein kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding,K07200//Insulin signaling pathway;Hypertrophic cardiomyopathy (HCM);Adipocytokine signaling pathway
55711,25,1,46,30,23,0,41,0,32,0,10,0,FAR2;fatty acyl CoA reductase 2,GO:0005777//peroxisome;GO:0005789//endoplasmic reticulum membrane;GO:0005782//peroxisomal matrix;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane,GO:0044255//cellular lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0008611//ether lipid biosynthetic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process,GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity;GO:0050062//long-chain-fatty-acyl-CoA reductase activity,"K13356//Cutin, suberine and wax biosynthesis;Peroxisome"
55713,0,0,0,18,43,41,24,0,6,0,0,1,ZNF334;zinc finger protein 334,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
55714,94,0,0,0,1,0,43,92,154,1,0,0,TENM3;teneurin transmembrane protein 3,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0030424//axon,GO:0010976//positive regulation of neuron projection development;GO:0097264//self proteolysis;GO:0048593//camera-type eye morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007165//signal transduction,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K06252//Focal adhesion;ECM-receptor interaction
55715,0,34,1,32,125,0,0,0,18,0,8,0,DOK4;docking protein 4,-,GO:0007399//nervous system development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0000165//MAPK cascade,GO:0005515//protein binding;GO:0005057//receptor signaling protein activity;GO:0005158//insulin receptor binding,K14752//Measles
55717,0,100,0,12,98,11,21,47,30,0,0,325,WDR11;WD repeat domain 11,GO:0016021//integral component of membrane;GO:0005929//cilium;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005634//nucleus,-,GO:0005515//protein binding,-
55718,60,0,1,15,39,0,0,0,6,133,0,0,POLR3E;polymerase (RNA) III (DNA directed) polypeptide E (80kD),GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex,GO:0006386//termination of RNA polymerase III transcription;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression;GO:0051607//defense response to virus;GO:0006383//transcription from RNA polymerase III promoter;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production,GO:0001056//RNA polymerase III activity,K14721//Cytosolic DNA-sensing pathway;Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism
55719,0,20,0,46,101,33,91,132,64,221,49,0,"FAM178A;family with sequence similarity 178, member A",GO:0000785//chromatin;GO:0005634//nucleus;GO:0005615//extracellular space,-,-,K06521//Axon guidance
55720,79,151,242,437,741,1,0,139,50,0,523,0,"TSR1;TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)",GO:0005730//nucleolus,GO:0042255//ribosome assembly,GO:0044822//poly(A) RNA binding,-
55721,0,0,80,0,0,9,0,0,43,0,5,0,IQCC;IQ motif containing C,-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
55722,2,0,0,0,0,0,46,16,41,0,0,1,CEP72;centrosomal protein 72kDa,GO:0005813//centrosome;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007051//spindle organization;GO:0033566//gamma-tubulin complex localization,GO:0042802//identical protein binding;GO:0005515//protein binding,K11092//Spliceosome
55723,0,0,0,0,0,0,0,1,0,0,0,0,ASF1B;anti-silencing function 1B histone chaperone,GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0030154//cell differentiation",GO:0042393//histone binding;GO:0005515//protein binding,-
55726,0,0,0,0,14,21,39,0,21,0,17,0,ASUN;asunder spermatogenesis regulator,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0080154//regulation of fertilization;GO:0030317//sperm motility;GO:0007346//regulation of mitotic cell cycle;GO:0007052//mitotic spindle organization;GO:0051642//centrosome localization;GO:0007067//mitotic nuclear division,GO:0005515//protein binding,-
55727,39,2,0,4,74,0,0,153,53,1,28,0,BTBD7;BTB (POZ) domain containing 7,GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0060693//regulation of branching involved in salivary gland morphogenesis,-,-
55728,0,0,1,20,117,73,38,0,71,0,9,0,N4BP2;NEDD4 binding protein 2,GO:0005829//cytosol,GO:0016310//phosphorylation;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0005515//protein binding;GO:0046404//ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity;GO:0004519//endonuclease activity;GO:0005524//ATP binding,-
55729,0,2,2,62,302,0,4,1,21,391,1,0,ATF7IP;activating transcription factor 7 interacting protein,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0006306//DNA methylation;GO:0045898//regulation of RNA polymerase II transcriptional preinitiation complex assembly",GO:0005515//protein binding,K04573//Amyotrophic lateral sclerosis (ALS);K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K09880//Cysteine and methionine metabolism;K11294//Pathogenic Escherichia coli infection;K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Calcium signaling pathway;Gastric acid secretion;K11447//Transcriptional misregulation in cancer
5573,125,9,44,75,336,0,24,0,73,0,1,0,"PRKAR1A;protein kinase, cAMP-dependent, regulatory, type I, alpha",GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0031594//neuromuscular junction;GO:0043234//protein complex;GO:0031588//AMP-activated protein kinase complex;GO:0005952//cAMP-dependent protein kinase complex,GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process;GO:0045214//sarcomere organization;GO:0034199//activation of protein kinase A activity;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006833//water transport;GO:0060038//cardiac muscle cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007143//female meiotic division;GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0055085//transmembrane transport;GO:0050796//regulation of insulin secretion;GO:0045835//negative regulation of meiosis;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0001707//mesoderm formation;GO:0045087//innate immune response;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0034236//protein kinase A catalytic subunit binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0030552//cAMP binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity,K04739//Insulin signaling pathway;Apoptosis
55731,9,25,50,0,18,21,9,63,20,40,65,0,"FAM222B;family with sequence similarity 222, member B",-,-,-,-
55732,108,0,0,9,27,0,39,0,11,149,16,0,C1orf112;chromosome 1 open reading frame 112,-,-,-,-
55733,0,0,0,0,0,0,12,0,43,0,0,0,HHAT;hedgehog acyltransferase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0007224//smoothened signaling pathway;GO:0018345//protein palmitoylation;GO:0007275//multicellular organismal development,GO:0005525//GTP binding;GO:0016409//palmitoyltransferase activity,-
55734,0,1,0,3,13,0,1,49,28,0,7,0,ZFP64;ZFP64 zinc finger protein,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
55735,171,0,0,28,17,16,22,120,33,0,64,218,"DNAJC11;DnaJ (Hsp40) homolog, subfamily C, member 11",GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,-,GO:0005515//protein binding,-
55737,0,51,2,42,126,0,21,0,0,0,0,0,VPS35;vacuolar protein sorting 35 homolog (S. cerevisiae),GO:0005829//cytosol;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0030904//retromer complex;GO:0005765//lysosomal membrane,"GO:0008219//cell death;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi",GO:0005515//protein binding,-
55738,0,0,0,1,0,0,0,75,12,82,7,0,ARFGAP1;ADP-ribosylation factor GTPase activating protein 1,GO:0030660//Golgi-associated vesicle membrane;GO:0045202//synapse;GO:0005829//cytosol,"GO:0032312//regulation of ARF GTPase activity;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0043547//positive regulation of GTPase activity;GO:0048205//COPI coating of Golgi vesicle;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0015031//protein transport;GO:0061024//membrane organization",GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K12492//Endocytosis
55739,0,21,0,7,57,6,19,2,0,0,0,0,CARKD;carbohydrate kinase domain containing,GO:0005739//mitochondrion,GO:0046496//nicotinamide nucleotide metabolic process,GO:0047453//ATP-dependent NAD(P)H-hydrate dehydratase activity;GO:0005524//ATP binding,-
55740,46,3,0,55,102,8,19,141,54,1,9,0,ENAH;enabled homolog (Drosophila),GO:0001725//stress fiber;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0030175//filopodium,GO:0008154//actin polymerization or depolymerization;GO:0046907//intracellular transport;GO:0001843//neural tube closure;GO:0050852//T cell receptor signaling pathway;GO:0007411//axon guidance,GO:0003779//actin binding;GO:0050699//WW domain binding;GO:0017124//SH3 domain binding;GO:0005515//protein binding,K05746//Regulation of actin cytoskeleton
55741,0,0,0,0,0,13,0,0,0,0,0,0,"EDEM2;ER degradation enhancer, mannosidase alpha-like 2",GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane;GO:0005576//extracellular region,GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006986//response to unfolded protein;GO:0006457//protein folding,"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005509//calcium ion binding",K10085//Protein processing in endoplasmic reticulum
55742,0,52,0,86,279,0,0,103,97,0,1,359,"PARVA;parvin, alpha",GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0005886//plasma membrane,GO:0060271//cilium morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0002040//sprouting angiogenesis;GO:0071670//smooth muscle cell chemotaxis;GO:0070252//actin-mediated cell contraction;GO:0034446//substrate adhesion-dependent cell spreading;GO:0034113//heterotypic cell-cell adhesion;GO:0034329//cell junction assembly;GO:0031532//actin cytoskeleton reorganization;GO:0007163//establishment or maintenance of cell polarity;GO:0008360//regulation of cell shape,GO:0005515//protein binding;GO:0003779//actin binding,K06275//Focal adhesion
55743,61,0,0,0,22,0,0,1,89,0,0,0,"CHFR;checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0016605//PML body,GO:0007067//mitotic nuclear division;GO:0019941//modification-dependent protein catabolic process;GO:0000209//protein polyubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007093//mitotic cell cycle checkpoint,GO:0016874//ligase activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
55744,0,0,0,7,37,0,6,0,0,0,0,0,COA1;cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae),GO:0005739//mitochondrion;GO:0031305//integral component of mitochondrial inner membrane;GO:0005737//cytoplasm,GO:0033617//mitochondrial respiratory chain complex IV assembly;GO:0032981//mitochondrial respiratory chain complex I assembly,-,K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
55745,69,37,0,3,90,24,0,11,16,0,0,0,"AP5M1;adaptor-related protein complex 5, mu 1 subunit",GO:0005764//lysosome;GO:0030119//AP-type membrane coat adaptor complex;GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0030131//clathrin adaptor complex;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0005770//late endosome,GO:0016192//vesicle-mediated transport;GO:0016197//endosomal transport;GO:0006886//intracellular protein transport,-,-
55746,152,52,1,35,42,0,0,0,16,1,0,0,NUP133;nucleoporin 133kDa,GO:0005635//nuclear envelope;GO:0005643//nuclear pore;GO:0000940//condensed chromosome outer kinetochore;GO:0031080//nuclear pore outer ring;GO:0005829//cytosol;GO:0016020//membrane;GO:0000777//condensed chromosome kinetochore,GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0048339//paraxial mesoderm development;GO:0015758//glucose transport;GO:0006999//nuclear pore organization;GO:0044281//small molecule metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0006406//mRNA export from nucleus;GO:0010827//regulation of glucose transport,GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding,K14300//RNA transport
55748,0,73,2,133,185,40,17,0,20,0,18,0,CNDP2;CNDP dipeptidase 2 (metallopeptidase M20 family),GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:1901687//glutathione derivative biosynthetic process;GO:0006750//glutathione biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006508//proteolysis,GO:0004180//carboxypeptidase activity;GO:0034701//tripeptidase activity;GO:0008237//metallopeptidase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding,K08660//Arginine and proline metabolism;Histidine metabolism;beta-Alanine metabolism;Metabolic pathways
55749,0,0,0,31,36,6,0,0,75,0,0,0,CCAR1;cell division cycle and apoptosis regulator 1,GO:0048471//perinuclear region of cytoplasm;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0006915//apoptotic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer
5575,149,13,21,9,3,13,0,148,28,0,64,0,"PRKAR1B;protein kinase, cAMP-dependent, regulatory, type I, beta",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005952//cAMP-dependent protein kinase complex,GO:0007202//activation of phospholipase C activity;GO:0055085//transmembrane transport;GO:0050796//regulation of insulin secretion;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007611//learning or memory;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:0006468//protein phosphorylation;GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process;GO:0034199//activation of protein kinase A activity;GO:0007165//signal transduction;GO:0006833//water transport;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0030552//cAMP binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0004862//cAMP-dependent protein kinase inhibitor activity,K04739//Apoptosis;Insulin signaling pathway
55750,0,16,0,4,3,14,21,0,65,0,1,0,AGK;acylglycerol kinase,GO:0043231//intracellular membrane-bounded organelle;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion,GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0046834//lipid phosphorylation;GO:0046486//glycerolipid metabolic process;GO:0046513//ceramide biosynthetic process,GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0001729//ceramide kinase activity;GO:0005524//ATP binding;GO:0047620//acylglycerol kinase activity,K09881//Glycerolipid metabolism;Metabolic pathways
55751,0,32,27,20,21,18,98,0,47,0,0,0,TMEM184C;transmembrane protein 184C,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
55752,166,9,0,0,55,0,40,0,37,0,0,0,SEPT11;septin 11,GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0030424//axon;GO:0031105//septin complex;GO:0030054//cell junction;GO:0043197//dendritic spine;GO:0001725//stress fiber,GO:0007049//cell cycle;GO:0051291//protein heterooligomerization;GO:0051301//cell division,GO:0005515//protein binding;GO:0005525//GTP binding,K04557//Parkinson's disease
55753,0,0,0,0,11,7,0,64,29,0,1,0,OGDHL;oxoglutarate dehydrogenase-like,GO:0005759//mitochondrial matrix,GO:0006096//glycolytic process;GO:0006099//tricarboxylic acid cycle,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004591//oxoglutarate dehydrogenase (succinyl-transferring) activity;GO:0030976//thiamine pyrophosphate binding,K00164//Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Citrate cycle (TCA cycle);Metabolic pathways;Microbial metabolism in diverse environments
55754,0,28,0,17,0,0,0,1,10,0,3,554,TMEM30A;transmembrane protein 30A,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0030658//transport vesicle membrane;GO:0016324//apical plasma membrane,GO:0010976//positive regulation of neuron projection development;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:0045332//phospholipid translocation;GO:0006855//drug transmembrane transport;GO:0036010//protein localization to endosome,GO:0005515//protein binding,-
55755,235,0,47,17,19,17,69,0,32,0,0,305,CDK5RAP2;CDK5 regulatory subunit associated protein 2,GO:0048471//perinuclear region of cytoplasm;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0000242//pericentriolar material;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,"GO:0001578//microtubule bundle formation;GO:0045665//negative regulation of neuron differentiation;GO:0000132//establishment of mitotic spindle orientation;GO:0046600//negative regulation of centriole replication;GO:0051297//centrosome organization;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007420//brain development;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0007059//chromosome segregation;GO:0022008//neurogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045664//regulation of neuron differentiation;GO:0090231//regulation of spindle checkpoint",GO:0005516//calmodulin binding;GO:0015631//tubulin binding;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding,K12478//Phagosome;Endocytosis;Tuberculosis;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
55756,0,0,0,0,0,0,11,0,34,97,0,0,INTS9;integrator complex subunit 9,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032039//integrator complex;GO:0005730//nucleolus,GO:0016180//snRNA processing,GO:0005515//protein binding,-
55757,0,0,0,13,23,34,64,54,102,0,0,0,UGGT2;UDP-glucose glycoprotein glucosyltransferase 2,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005788//endoplasmic reticulum lumen,GO:0097359//UDP-glucosylation;GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0003980//UDP-glucose:glycoprotein glucosyltransferase activity,K11718//Protein processing in endoplasmic reticulum
55758,0,17,1,10,57,0,12,82,38,0,0,1,RCOR3;REST corepressor 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0003677//DNA binding,K11829//Huntington's disease
55759,0,0,0,11,22,0,18,0,29,0,6,0,WDR12;WD repeat domain 12,"GO:0070545//PeBoW complex;GO:0005654//nucleoplasm;GO:0030687//preribosome, large subunit precursor;GO:0005730//nucleolus","GO:0042273//ribosomal large subunit biogenesis;GO:0000466//maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0008283//cell proliferation;GO:0000463//maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007219//Notch signaling pathway",GO:0043021//ribonucleoprotein complex binding;GO:0005515//protein binding,-
5576,0,0,0,25,55,28,0,0,36,0,0,0,"PRKAR2A;protein kinase, cAMP-dependent, regulatory, type II, alpha",GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0031588//AMP-activated protein kinase complex;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005952//cAMP-dependent protein kinase complex;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0006112//energy reserve metabolic process;GO:0007596//blood coagulation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006833//water transport;GO:0007165//signal transduction;GO:0034199//activation of protein kinase A activity;GO:0050796//regulation of insulin secretion;GO:0055085//transmembrane transport;GO:0035556//intracellular signal transduction;GO:0007202//activation of phospholipase C activity;GO:0071377//cellular response to glucagon stimulus;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0044281//small molecule metabolic process;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0034236//protein kinase A catalytic subunit binding;GO:0031625//ubiquitin protein ligase binding;GO:0030552//cAMP binding;GO:0005515//protein binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0004862//cAMP-dependent protein kinase inhibitor activity,K04739//Apoptosis;Insulin signaling pathway
55760,0,28,57,96,147,0,25,54,29,0,57,0,DHX32;DEAH (Asp-Glu-Ala-His) box polypeptide 32,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0004386//helicase activity;GO:0005524//ATP binding,-
55761,74,0,1,0,14,12,0,0,0,55,0,0,TTC17;tetratricopeptide repeat domain 17,GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm,GO:0044782//cilium organization;GO:0030041//actin filament polymerization,GO:0005515//protein binding,-
55762,73,0,0,0,6,21,62,0,33,150,7,0,ZNF701;zinc finger protein 701,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
55763,0,0,0,1,3,12,0,0,36,0,0,0,EXOC1;exocyst complex component 1,GO:0000145//exocyst;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0061024//membrane organization;GO:0015031//protein transport;GO:0044267//cellular protein metabolic process;GO:0006887//exocytosis,GO:0005515//protein binding,-
55764,0,0,0,14,34,59,27,1,51,0,0,0,IFT122;intraflagellar transport 122,GO:0036064//ciliary basal body;GO:0016020//membrane;GO:0072372//primary cilium;GO:0032391//photoreceptor connecting cilium;GO:0030991//intraciliary transport particle A;GO:0005737//cytoplasm,GO:0048593//camera-type eye morphogenesis;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway;GO:0045879//negative regulation of smoothened signaling pathway;GO:0061512//protein localization to cilium;GO:0072594//establishment of protein localization to organelle;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0042733//embryonic digit morphogenesis;GO:0060971//embryonic heart tube left/right pattern formation;GO:0060173//limb development;GO:0060271//cilium morphogenesis;GO:0035721//intraciliary retrograde transport;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0035115//embryonic forelimb morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001843//neural tube closure;GO:0035050//embryonic heart tube development;GO:0010172//embryonic body morphogenesis,GO:0005515//protein binding,K12602//RNA degradation;K03130//Herpes simplex infection;Basal transcription factors
55765,5,0,0,0,0,0,19,0,1,51,0,0,C1orf106;chromosome 1 open reading frame 106,-,-,-,K12817//Spliceosome;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
55766,0,64,2,30,95,0,0,0,0,0,4,0,"H2AFJ;H2A histone family, member J",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Systemic lupus erythematosus;Alcoholism
55768,0,0,0,17,33,22,21,0,8,0,0,2,NGLY1;N-glycanase 1,GO:0005737//cytoplasm,GO:0006516//glycoprotein catabolic process,GO:0000224//peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K01456//Protein processing in endoplasmic reticulum
55769,0,42,0,23,68,0,0,0,45,0,0,0,ZNF83;zinc finger protein 83,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
5577,24,0,0,4,12,9,1,0,0,0,0,0,"PRKAR2B;protein kinase, cAMP-dependent, regulatory, type II, beta",GO:0005952//cAMP-dependent protein kinase complex;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0043198//dendritic shaft;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0097546//ciliary base;GO:0005829//cytosol,GO:0007596//blood coagulation;GO:0006112//energy reserve metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034199//activation of protein kinase A activity;GO:0007165//signal transduction;GO:0006833//water transport;GO:0050796//regulation of insulin secretion;GO:0007202//activation of phospholipase C activity;GO:0055085//transmembrane transport;GO:0035556//intracellular signal transduction;GO:0006631//fatty acid metabolic process;GO:0007612//learning;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0071377//cellular response to glucagon stimulus;GO:2000480//negative regulation of cAMP-dependent protein kinase activity;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0004862//cAMP-dependent protein kinase inhibitor activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0031625//ubiquitin protein ligase binding;GO:0008603//cAMP-dependent protein kinase regulator activity;GO:0030552//cAMP binding,K04739//Insulin signaling pathway;Apoptosis
55770,0,0,1,20,50,10,0,0,4,32,14,0,EXOC2;exocyst complex component 2,GO:0000145//exocyst;GO:0005886//plasma membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane,GO:0044267//cellular protein metabolic process;GO:0061024//membrane organization;GO:0006893//Golgi to plasma membrane transport;GO:0015031//protein transport;GO:0006887//exocytosis,GO:0005515//protein binding;GO:0017160//Ral GTPase binding;GO:0047485//protein N-terminus binding,-
55771,66,0,0,0,0,29,0,100,31,0,0,0,PRR11;proline rich 11,GO:0016020//membrane;GO:0005737//cytoplasm,-,-,K11447//Transcriptional misregulation in cancer
55773,0,0,0,11,16,7,0,0,27,0,0,0,"TBC1D23;TBC1 domain family, member 23",-,GO:0050727//regulation of inflammatory response;GO:0032755//positive regulation of interleukin-6 production;GO:0032680//regulation of tumor necrosis factor production;GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,K04707//Pathways in cancer;Insulin signaling pathway;Jak-STAT signaling pathway;Endocytosis;Bacterial invasion of epithelial cells;Ubiquitin mediated proteolysis;T cell receptor signaling pathway;Chronic myeloid leukemia;Measles;ErbB signaling pathway
55775,0,22,9,1,0,0,41,0,40,167,0,0,TDP1;tyrosyl-DNA phosphodiesterase 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0000012//single strand break repair;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004527//exonuclease activity;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding;GO:0017005//3'-tyrosyl-DNA phosphodiesterase activity;GO:0003690//double-stranded DNA binding,-
55776,0,0,0,12,18,0,0,0,39,0,0,0,SAYSD1;SAYSVFN motif domain containing 1,GO:0030659//cytoplasmic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane,-,-,-
55777,0,1,0,0,6,0,0,0,64,0,10,266,MBD5;methyl-CpG binding domain protein 5,GO:0010369//chromocenter;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0044708//single-organism behavior;GO:0040014//regulation of multicellular organism growth;GO:0060399//positive regulation of growth hormone receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0007399//nervous system development,GO:0003677//DNA binding;GO:0003682//chromatin binding,-
55778,46,131,37,31,219,30,17,50,69,0,212,0,ZNF839;zinc finger protein 839,-,-,GO:0046872//metal ion binding,K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
55779,96,0,0,4,1,31,52,0,105,38,20,0,WDR52;WD repeat domain 52,-,-,-,-
5578,0,14,0,16,27,0,0,67,25,0,3,0,"PRKCA;protein kinase C, alpha",GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0001750//photoreceptor outer segment;GO:0005654//nucleoplasm;GO:0045177//apical part of cell,"GO:0002026//regulation of the force of heart contraction;GO:0071322//cellular response to carbohydrate stimulus;GO:0030168//platelet activation;GO:0016070//RNA metabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035408//histone H3-T6 phosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0036289//peptidyl-serine autophosphorylation;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0016056//rhodopsin mediated signaling pathway;GO:0006112//energy reserve metabolic process;GO:2000707//positive regulation of dense core granule biogenesis;GO:0000188//inactivation of MAPK activity;GO:0050729//positive regulation of inflammatory response;GO:0007596//blood coagulation;GO:0002159//desmosome assembly;GO:0001525//angiogenesis;GO:0045087//innate immune response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045931//positive regulation of mitotic cell cycle;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0050930//induction of positive chemotaxis;GO:0045785//positive regulation of cell adhesion;GO:0007165//signal transduction;GO:0016071//mRNA metabolic process;GO:0046325//negative regulation of glucose import;GO:0070555//response to interleukin-1;GO:0006468//protein phosphorylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0007268//synaptic transmission;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0090330//regulation of platelet aggregation;GO:0006937//regulation of muscle contraction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0045651//positive regulation of macrophage differentiation;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0045766//positive regulation of angiogenesis;GO:0034351//negative regulation of glial cell apoptotic process;GO:0006874//cellular calcium ion homeostasis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0030335//positive regulation of cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007202//activation of phospholipase C activity;GO:0007194//negative regulation of adenylate cyclase activity;GO:0002062//chondrocyte differentiation;GO:0050796//regulation of insulin secretion;GO:0007603//phototransduction, visible light;GO:0007190//activation of adenylate cyclase activity;GO:0030593//neutrophil chemotaxis",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004698//calcium-dependent protein kinase C activity;GO:0035403//histone kinase activity (H3-T6 specific);GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0004697//protein kinase C activity;GO:0005524//ATP binding,K02677//Salivary secretion;B cell receptor signaling pathway;GABAergic synapse;Tight junction;Cholinergic synapse;Fc epsilon RI signaling pathway;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;Aldosterone-regulated sodium reabsorption;African trypanosomiasis;Pancreatic secretion;Carbohydrate digestion and absorption;Long-term potentiation;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Phototransduction - fly;Amoebiasis;Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Vascular smooth muscle contraction;Wnt signaling pathway;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Long-term depression;Glioma;Gastric acid secretion;Pathogenic Escherichia coli infection;VEGF signaling pathway;Focal adhesion;Leishmaniasis;Serotonergic synapse;Influenza A;GnRH signaling pathway;Chemokine signaling pathway;Pathways in cancer;Dopaminergic synapse;Gap junction;NF-kappa B signaling pathway;ErbB signaling pathway;MAPK signaling pathway;Morphine addiction
55780,0,0,0,6,18,44,0,0,20,0,0,3,ERMARD;ER membrane-associated RNA degradation,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development,-,-
55781,0,37,0,24,0,18,53,0,22,0,2,0,RIOK2;RIO kinase 2,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K07179//Ribosome biogenesis in eukaryotes
55783,0,53,1,29,54,0,0,0,16,0,0,0,CMTR2;cap methyltransferase 2,GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006370//7-methylguanosine mRNA capping;GO:0097310//cap2 mRNA methylation,GO:0004483//mRNA (nucleoside-2'-O-)-methyltransferase activity,-
55784,0,20,0,4,11,21,0,17,32,0,0,0,"MCTP2;multiple C2 domains, transmembrane 2",GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0019722//calcium-mediated signaling,GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,K02677//Leishmaniasis;VEGF signaling pathway;Focal adhesion;Glioma;Pathogenic Escherichia coli infection;Gastric acid secretion;Long-term depression;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Morphine addiction;MAPK signaling pathway;ErbB signaling pathway;NF-kappa B signaling pathway;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Gap junction;Dopaminergic synapse;Influenza A;Serotonergic synapse;Non-small cell lung cancer;Vibrio cholerae infection;Melanogenesis;Cholinergic synapse;Fc epsilon RI signaling pathway;Tight junction;GABAergic synapse;B cell receptor signaling pathway;Salivary secretion;Vascular smooth muscle contraction;Wnt signaling pathway;Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Amoebiasis;Phototransduction - fly;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Long-term potentiation;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;African trypanosomiasis;Pancreatic secretion;K15293//Synaptic vesicle cycle
55785,202,0,0,0,8,20,99,52,52,1,1,0,"FGD6;FYVE, RhoGEF and PH domain containing 6",GO:0001726//ruffle;GO:0005794//Golgi apparatus;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0032321//positive regulation of Rho GTPase activity;GO:0043088//regulation of Cdc42 GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0046847//filopodium assembly;GO:0008360//regulation of cell shape;GO:0043547//positive regulation of GTPase activity;GO:0007010//cytoskeleton organization,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0031267//small GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding,-
55786,0,0,0,0,1,0,12,0,0,0,0,0,ZNF415;zinc finger protein 415,GO:0005737//cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
55787,0,0,52,30,39,0,0,0,17,0,11,311,TXLNG;taxilin gamma,GO:0031965//nuclear membrane;GO:0005829//cytosol,"GO:0006351//transcription, DNA-templated;GO:0030500//regulation of bone mineralization;GO:0007049//cell cycle;GO:0010564//regulation of cell cycle process;GO:0051726//regulation of cell cycle;GO:0006355//regulation of transcription, DNA-templated",GO:0019905//syntaxin binding;GO:0046982//protein heterodimerization activity,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K06106//Shigellosis;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction
55788,0,0,14,0,9,0,0,0,24,0,0,0,LMBRD1;LMBR1 domain containing 1,GO:0016021//integral component of membrane;GO:0045334//clathrin-coated endocytic vesicle;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane,GO:0006766//vitamin metabolic process;GO:0009235//cobalamin metabolic process;GO:0051898//negative regulation of protein kinase B signaling;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0016032//viral process;GO:0046325//negative regulation of glucose import;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0031419//cobalamin binding;GO:0005158//insulin receptor binding,K14617//Vitamin digestion and absorption
55789,0,0,0,1,0,13,0,0,0,13,0,0,DEPDC1B;DEP domain containing 1B,GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,-
5579,0,0,0,0,0,47,29,0,8,0,0,0,"PRKCB;protein kinase C, beta",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0007596//blood coagulation;GO:0006915//apoptotic process;GO:0010829//negative regulation of glucose transport;GO:0030168//platelet activation;GO:0042113//B cell activation;GO:0071322//cellular response to carbohydrate stimulus;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0035408//histone H3-T6 phosphorylation;GO:0035556//intracellular signal transduction;GO:0006816//calcium ion transport;GO:0006351//transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042953//lipoprotein transport;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0050853//B cell receptor signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0045766//positive regulation of angiogenesis",GO:0005515//protein binding;GO:0042393//histone binding;GO:0004674//protein serine/threonine kinase activity;GO:0008270//zinc ion binding;GO:0035403//histone kinase activity (H3-T6 specific);GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0005080//protein kinase C binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0005246//calcium channel regulator activity,K02677//Wnt signaling pathway;Vascular smooth muscle contraction;Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Amoebiasis;Phototransduction - fly;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Carbohydrate digestion and absorption;Long-term potentiation;Aldosterone-regulated sodium reabsorption;African trypanosomiasis;Pancreatic secretion;Non-small cell lung cancer;Vibrio cholerae infection;Melanogenesis;Cholinergic synapse;Fc epsilon RI signaling pathway;GABAergic synapse;Tight junction;B cell receptor signaling pathway;Salivary secretion;Morphine addiction;MAPK signaling pathway;ErbB signaling pathway;NF-kappa B signaling pathway;GnRH signaling pathway;Chemokine signaling pathway;Pathways in cancer;Dopaminergic synapse;Gap junction;Influenza A;Serotonergic synapse;Leishmaniasis;VEGF signaling pathway;Focal adhesion;Glioma;Pathogenic Escherichia coli infection;Gastric acid secretion;Long-term depression;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Calcium signaling pathway;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption
55790,156,98,79,61,100,0,11,71,84,0,10,0,CSGALNACT1;chondroitin sulfate N-acetylgalactosaminyltransferase 1,GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane;GO:0005622//intracellular,"GO:0030210//heparin biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0001958//endochondral ossification;GO:0030203//glycosaminoglycan metabolic process;GO:0015014//heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0050653//chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;GO:0008037//cell recognition;GO:0007399//nervous system development;GO:0030198//extracellular matrix organization;GO:0030166//proteoglycan biosynthetic process;GO:0046398//UDP-glucuronate metabolic process;GO:0044281//small molecule metabolic process;GO:0051216//cartilage development;GO:0008283//cell proliferation;GO:0050651//dermatan sulfate proteoglycan biosynthetic process;GO:0019276//UDP-N-acetylgalactosamine metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0030204//chondroitin sulfate metabolic process;GO:0050650//chondroitin sulfate proteoglycan biosynthetic process",GO:0008955//peptidoglycan glycosyltransferase activity;GO:0008376//acetylgalactosaminyltransferase activity;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity;GO:0015020//glucuronosyltransferase activity;GO:0046872//metal ion binding;GO:0047237//glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,K00746//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways
55791,0,0,0,5,51,0,0,35,0,0,0,0,LRIF1;ligand dependent nuclear receptor interacting factor 1,GO:0015629//actin cytoskeleton;GO:0016363//nuclear matrix;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0042974//retinoic acid receptor binding;GO:0005515//protein binding,-
55793,0,0,24,11,0,0,0,10,41,0,11,45,"FAM63A;family with sequence similarity 63, member A",GO:0070062//extracellular vesicular exosome,-,-,-
55794,0,26,0,6,21,0,0,0,14,0,0,0,DDX28;DEAD (Asp-Glu-Ala-Asp) box polypeptide 28,GO:0005634//nucleus;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0044822//poly(A) RNA binding,-
55795,0,19,0,8,54,0,0,0,44,0,27,0,PCID2;PCI domain containing 2,-,"GO:0043488//regulation of mRNA stability;GO:2000117//negative regulation of cysteine-type endopeptidase activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0048536//spleen development;GO:0043066//negative regulation of apoptotic process",-,-
55796,0,1,0,2,44,7,0,0,35,0,0,0,MBNL3;muscleblind-like splicing regulator 3,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045662//negative regulation of myoblast differentiation;GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0007275//multicellular organismal development;GO:0008380//RNA splicing,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
55798,0,0,0,10,40,0,36,0,8,0,0,343,METTL2B;methyltransferase like 2B,-,GO:0030488//tRNA methylation,GO:0016427//tRNA (cytosine) methyltransferase activity,K00599//Histidine metabolism;Microbial metabolism in diverse environments;Tyrosine metabolism;Metabolic pathways;Lipopolysaccharide biosynthesis;Polycyclic aromatic hydrocarbon degradation
55799,0,0,0,0,0,0,0,58,61,139,0,0,"CACNA2D3;calcium channel, voltage-dependent, alpha 2/delta subunit 3",GO:0016021//integral component of membrane,GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding,K04860//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Cardiac muscle contraction;Dilated cardiomyopathy
558,46,0,0,5,0,0,7,60,0,0,16,0,AXL;AXL receptor tyrosine kinase,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0001764//neuron migration;GO:0032720//negative regulation of tumor necrosis factor production;GO:0021885//forebrain cell migration;GO:0007283//spermatogenesis;GO:0031668//cellular response to extracellular stimulus;GO:0032940//secretion by cell;GO:0043524//negative regulation of neuron apoptotic process;GO:0042698//ovulation cycle;GO:0006909//phagocytosis;GO:0071222//cellular response to lipopolysaccharide;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030168//platelet activation;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0045087//innate immune response;GO:0043491//protein kinase B signaling;GO:0048469//cell maturation;GO:0035457//cellular response to interferon-alpha;GO:2000669//negative regulation of dendritic cell apoptotic process;GO:0032689//negative regulation of interferon-gamma production;GO:0034101//erythrocyte homeostasis;GO:0032825//positive regulation of natural killer cell differentiation;GO:0001779//natural killer cell differentiation;GO:0006954//inflammatory response;GO:0007165//signal transduction;GO:0051250//negative regulation of lymphocyte activation;GO:0070301//cellular response to hydrogen peroxide;GO:0043277//apoptotic cell clearance;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031100//organ regeneration;GO:0060068//vagina development;GO:0097028//dendritic cell differentiation;GO:0001974//blood vessel remodeling,GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0005524//ATP binding;GO:0032036//myosin heavy chain binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0001786//phosphatidylserine binding,-
5580,56,39,2,13,145,0,33,0,28,0,15,0,"PRKCD;protein kinase C, delta",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0016363//nuclear matrix;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0016071//mRNA metabolic process;GO:0007165//signal transduction;GO:0023021//termination of signal transduction;GO:1900163//positive regulation of phospholipid scramblase activity;GO:0050728//negative regulation of inflammatory response;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010469//regulation of receptor activity;GO:0042100//B cell proliferation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0090398//cellular senescence;GO:0034351//negative regulation of glial cell apoptotic process;GO:0007202//activation of phospholipase C activity;GO:0018108//peptidyl-tyrosine phosphorylation;GO:2000755//positive regulation of sphingomyelin catabolic process;GO:0050821//protein stabilization;GO:0051490//negative regulation of filopodium assembly;GO:0030168//platelet activation;GO:0016070//RNA metabolic process;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:2000753//positive regulation of glucosylceramide catabolic process;GO:0090331//negative regulation of platelet aggregation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0007596//blood coagulation;GO:0032615//interleukin-12 production;GO:0016064//immunoglobulin mediated immune response;GO:0030837//negative regulation of actin filament polymerization;GO:0032613//interleukin-10 production;GO:0007049//cell cycle;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0045087//innate immune response;GO:0010467//gene expression;GO:0032091//negative regulation of protein binding;GO:0042742//defense response to bacterium;GO:0032930//positive regulation of superoxide anion generation;GO:0042119//neutrophil activation;GO:0035307//positive regulation of protein dephosphorylation,GO:0004697//protein kinase C activity;GO:0008047//enzyme activator activity;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004699//calcium-independent protein kinase C activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043560//insulin receptor substrate binding,K06068//T cell receptor signaling pathway;Adipocytokine signaling pathway;Neurotrophin signaling pathway;Vascular smooth muscle contraction;Measles;Type II diabetes mellitus;Tight junction;Chemokine signaling pathway;GnRH signaling pathway;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis
55800,0,0,0,12,0,0,39,43,36,0,5,0,"SCN3B;sodium channel, voltage-gated, type III, beta subunit",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc;GO:0001518//voltage-gated sodium channel complex,GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0051899//membrane depolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0006814//sodium ion transport;GO:0019233//sensory perception of pain;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0086070//SA node cell to atrial cardiac muscle cell communication;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0072659//protein localization to plasma membrane;GO:0035725//sodium ion transmembrane transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0007411//axon guidance;GO:0086014//atrial cardiac muscle cell action potential;GO:0010765//positive regulation of sodium ion transport;GO:0060048//cardiac muscle contraction;GO:0010460//positive regulation of heart rate;GO:0086010//membrane depolarization during action potential;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential,GO:0017080//sodium channel regulator activity;GO:0044325//ion channel binding;GO:0005248//voltage-gated sodium channel activity;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential,-
55801,0,0,0,0,0,0,0,0,7,0,0,0,IL26;interleukin 26,GO:0005615//extracellular space;GO:0005829//cytosol,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0007267//cell-cell signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0050680//negative regulation of epithelial cell proliferation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050715//positive regulation of cytokine secretion;GO:0046427//positive regulation of JAK-STAT cascade,GO:0005125//cytokine activity,K05446//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
55802,0,20,0,0,14,22,0,0,34,0,8,0,DCP1A;decapping mRNA 1A,GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005829//cytosol;GO:0016020//membrane,"GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0010467//gene expression;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0016787//hydrolase activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K12610//RNA degradation
55803,0,0,0,0,0,33,0,0,12,0,13,0,ADAP2;ArfGAP with dual PH domains 2,GO:0005740//mitochondrial envelope;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007507//heart development;GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity,"GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0043533//inositol 1,3,4,5 tetrakisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0030674//protein binding, bridging;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005515//protein binding;GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding",K12486//Endocytosis
55805,0,0,0,7,0,0,34,0,75,0,0,0,LRP2BP;LRP2 binding protein,GO:0005737//cytoplasm,-,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
55806,0,0,0,2,14,40,22,0,37,0,0,0,HR;hair growth associated,GO:0016604//nuclear body;GO:0005634//nucleus,"GO:0055114//oxidation-reduction process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0016491//oxidoreductase activity,K11449//Transcriptional misregulation in cancer
55808,0,0,0,0,0,12,0,0,58,0,0,0,"ST6GALNAC1;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0097503//sialylation;GO:0006486//protein glycosylation;GO:0009312//oligosaccharide biosynthetic process,"GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity",K03479//Metabolic pathways;Mucin type O-Glycan biosynthesis
55809,0,0,49,0,0,14,75,0,61,0,0,0,TRERF1;transcriptional regulating factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0007275//multicellular organismal development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006707//cholesterol catabolic process;GO:0042592//homeostatic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006694//steroid biosynthetic process;GO:0046885//regulation of hormone biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated","GO:0003682//chromatin binding;GO:0008301//DNA binding, bending;GO:0046872//metal ion binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding",K11829//Huntington's disease
5581,67,0,37,3,1,12,2,0,42,131,23,0,"PRKCE;protein kinase C, epsilon",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0071944//cell periphery;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0051209//release of sequestered calcium ion into cytosol;GO:0035556//intracellular signal transduction;GO:0050996//positive regulation of lipid catabolic process;GO:0043410//positive regulation of MAPK cascade;GO:0045087//innate immune response;GO:0007049//cell cycle;GO:0035641//locomotory exploration behavior;GO:0070257//positive regulation of mucus secretion;GO:0007596//blood coagulation;GO:0007155//cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0010763//positive regulation of fibroblast migration;GO:0030168//platelet activation;GO:0002281//macrophage activation involved in immune response;GO:0071361//cellular response to ethanol;GO:0090303//positive regulation of wound healing;GO:0007202//activation of phospholipase C activity;GO:0010811//positive regulation of cell-substrate adhesion;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051301//cell division;GO:0035669//TRAM-dependent toll-like receptor 4 signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:2000273//positive regulation of receptor activity;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0071456//cellular response to hypoxia;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0006915//apoptotic process;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0010634//positive regulation of epithelial cell migration;GO:0006468//protein phosphorylation;GO:0030838//positive regulation of actin filament polymerization;GO:0043278//response to morphine;GO:0032467//positive regulation of cytokinesis;GO:2001031//positive regulation of cellular glucuronidation;GO:0007165//signal transduction",GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0008047//enzyme activator activity;GO:0003785//actin monomer binding;GO:0004699//calcium-independent protein kinase C activity;GO:0019899//enzyme binding;GO:0004871//signal transducer activity;GO:0030546//receptor activator activity;GO:0035276//ethanol binding;GO:0071889//14-3-3 protein binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K06068//Tight junction;Chemokine signaling pathway;GnRH signaling pathway;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;T cell receptor signaling pathway;Adipocytokine signaling pathway;Neurotrophin signaling pathway;Vascular smooth muscle contraction;Measles;Type II diabetes mellitus
55810,0,19,0,0,51,0,52,0,77,166,0,0,FOXJ2;forkhead box J2,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding,-
55812,0,0,0,0,17,0,0,0,19,0,0,0,SPATA7;spermatogenesis associated 7,-,GO:0007601//visual perception;GO:0050896//response to stimulus,-,-
55813,52,0,1,0,47,11,0,108,0,0,19,0,"UTP6;UTP6, small subunit (SSU) processome component, homolog (yeast)",GO:0005730//nucleolus,GO:0006364//rRNA processing,-,K14557//Ribosome biogenesis in eukaryotes
55814,35,31,24,49,200,4,37,59,74,0,31,0,"BDP1;B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006383//transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
55815,0,0,0,0,0,8,0,0,14,0,0,315,TSNAXIP1;translin-associated factor X interacting protein 1,GO:0048471//perinuclear region of cytoplasm,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,-,-
55816,80,0,0,0,0,19,0,0,1,0,5,0,DOK5;docking protein 5,-,GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007399//nervous system development;GO:0000165//MAPK cascade,GO:0005057//receptor signaling protein activity;GO:0005158//insulin receptor binding,K14752//Measles
55818,48,0,0,27,25,0,19,54,15,0,0,0,KDM3A;lysine (K)-specific demethylase 3A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,"GO:0006351//transcription, DNA-templated;GO:0036123//histone H3-K9 dimethylation;GO:0055114//oxidation-reduction process;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0030521//androgen receptor signaling pathway;GO:0046293//formaldehyde biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033169//histone H3-K9 demethylation;GO:0007290//spermatid nucleus elongation;GO:0009755//hormone-mediated signaling pathway",GO:0050681//androgen receptor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005506//iron ion binding;GO:0051213//dioxygenase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001047//core promoter binding,-
55819,0,47,0,6,1,0,0,0,0,0,1,0,RNF130;ring finger protein 130,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0016567//protein ubiquitination;GO:0006915//apoptotic process;GO:0012501//programmed cell death,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
5582,55,0,0,0,0,42,33,65,10,0,0,0,"PRKCG;protein kinase C, gamma",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005911//cell-cell junction;GO:0097060//synaptic membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008219//cell death;GO:0007611//learning or memory;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0032425//positive regulation of mismatch repair;GO:0007635//chemosensory behavior;GO:0007202//activation of phospholipase C activity;GO:0035556//intracellular signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0043278//response to morphine;GO:0016310//phosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0046777//protein autophosphorylation;GO:0060384//innervation;GO:0007596//blood coagulation;GO:0031397//negative regulation of protein ubiquitination;GO:0048265//response to pain;GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission;GO:0042177//negative regulation of protein catabolic process,GO:0004672//protein kinase activity;GO:0008270//zinc ion binding;GO:0004698//calcium-dependent protein kinase C activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004697//protein kinase C activity;GO:0005524//ATP binding,K02677//Vibrio cholerae infection;Melanogenesis;Non-small cell lung cancer;B cell receptor signaling pathway;Salivary secretion;GABAergic synapse;Tight junction;Fc epsilon RI signaling pathway;Cholinergic synapse;Phototransduction - fly;Amoebiasis;Natural killer cell mediated cytotoxicity;Glutamatergic synapse;Amphetamine addiction;Wnt signaling pathway;Vascular smooth muscle contraction;Pancreatic secretion;African trypanosomiasis;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Long-term potentiation;MAPK signaling pathway - yeast;Phosphatidylinositol signaling system;Pathogenic Escherichia coli infection;Glioma;Gastric acid secretion;Focal adhesion;VEGF signaling pathway;Leishmaniasis;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Retrograde endocannabinoid signaling;Calcium signaling pathway;Leukocyte transendothelial migration;Long-term depression;ErbB signaling pathway;MAPK signaling pathway;Morphine addiction;Serotonergic synapse;Influenza A;Dopaminergic synapse;Gap junction;GnRH signaling pathway;Chemokine signaling pathway;Pathways in cancer;NF-kappa B signaling pathway
55821,0,0,0,0,0,0,0,53,25,123,0,0,ALLC;allantoicase,-,GO:0000256//allantoin catabolic process,GO:0004037//allantoicase activity,K01477//Metabolic pathways;Microbial metabolism in diverse environments;Purine metabolism
55823,9,0,23,8,35,0,0,0,47,151,13,0,VPS11;vacuolar protein sorting 11 homolog (S. cerevisiae),GO:0030139//endocytic vesicle;GO:0005768//endosome;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport,GO:0008270//zinc ion binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
55824,2,1,0,7,0,17,19,0,74,0,5,0,PAG1;phosphoprotein membrane anchor with glycosphingolipid microdomains 1,GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050868//negative regulation of T cell activation;GO:0007165//signal transduction;GO:0050852//T cell receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0050863//regulation of T cell activation;GO:0009967//positive regulation of signal transduction,GO:0005515//protein binding;GO:0005070//SH3/SH2 adaptor activity;GO:0042169//SH2 domain binding,K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K08522//Neuroactive ligand-receptor interaction;Autoimmune thyroid disease;GnRH signaling pathway;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
55825,0,0,0,0,1,0,0,0,0,0,10,0,PECR;peroxisomal trans-2-enoyl-CoA reductase,GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle,GO:0006633//fatty acid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0033306//phytol metabolic process,"GO:0008670//2,4-dienoyl-CoA reductase (NADPH) activity;GO:0005102//receptor binding;GO:0019166//trans-2-enoyl-CoA reductase (NADPH) activity",K07753//Biosynthesis of unsaturated fatty acids;Peroxisome
55827,0,4,6,39,86,26,12,0,25,0,1,0,DCAF6;DDB1 and CUL4 associated factor 6,GO:0005634//nucleus;GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,-
55829,102,0,0,0,8,0,18,0,25,0,0,0,VIMP;VCP-interacting membrane protein,GO:0034362//low-density lipoprotein particle;GO:0034361//very-low-density lipoprotein particle;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005881//cytoplasmic microtubule;GO:0030176//integral component of endoplasmic reticulum membrane,"GO:0009749//response to glucose;GO:2000110//negative regulation of macrophage apoptotic process;GO:0051771//negative regulation of nitric-oxide synthase biosynthetic process;GO:0006111//regulation of gluconeogenesis;GO:0030970//retrograde protein transport, ER to cytosol;GO:0032869//cellular response to insulin stimulus;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0051775//response to redox state;GO:0034599//cellular response to oxidative stress;GO:0032715//negative regulation of interleukin-6 production;GO:0046325//negative regulation of glucose import;GO:0006983//ER overload response;GO:0071222//cellular response to lipopolysaccharide;GO:0080164//regulation of nitric oxide metabolic process;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045719//negative regulation of glycogen biosynthetic process;GO:0002865//negative regulation of acute inflammatory response to antigenic stimulus;GO:0045184//establishment of protein localization;GO:0032720//negative regulation of tumor necrosis factor production;GO:0045454//cell redox homeostasis;GO:0050728//negative regulation of inflammatory response",GO:0008430//selenium binding;GO:0016209//antioxidant activity;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0019899//enzyme binding,K14025//Protein processing in endoplasmic reticulum
5583,0,68,1,22,144,7,10,30,13,0,15,0,"PRKCH;protein kinase C, eta",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0034351//negative regulation of glial cell apoptotic process;GO:0045618//positive regulation of keratinocyte differentiation;GO:0007165//signal transduction;GO:0050861//positive regulation of B cell receptor signaling pathway;GO:0030168//platelet activation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007596//blood coagulation;GO:0070528//protein kinase C signaling;GO:0060252//positive regulation of glial cell proliferation;GO:0006468//protein phosphorylation;GO:2000810//regulation of tight junction assembly,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0017160//Ral GTPase binding;GO:0004699//calcium-independent protein kinase C activity;GO:0019899//enzyme binding,K06068//Fc gamma R-mediated phagocytosis;Chemokine signaling pathway;GnRH signaling pathway;Tight junction;Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;Measles;Type II diabetes mellitus;Adipocytokine signaling pathway;T cell receptor signaling pathway;Vascular smooth muscle contraction;Neurotrophin signaling pathway
55830,0,38,193,169,125,0,33,0,60,0,49,0,GLT8D1;glycosyltransferase 8 domain containing 1,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
55831,0,0,0,0,2,0,0,0,0,0,0,0,EMC3;ER membrane protein complex subunit 3,GO:0016021//integral component of membrane;GO:0072546//ER membrane protein complex,-,-,-
55832,56,75,0,30,162,13,0,0,22,0,0,0,CAND1;cullin-associated and neddylation-dissociated 1,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,GO:0030154//cell differentiation;GO:0010265//SCF complex assembly;GO:0045899//positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0043086//negative regulation of catalytic activity;GO:0016567//protein ubiquitination,GO:0017025//TBP-class protein binding;GO:0005515//protein binding,-
55833,150,24,0,10,27,3,80,0,17,65,0,0,UBAP2;ubiquitin associated protein 2,-,-,GO:0044822//poly(A) RNA binding,-
55835,0,0,0,0,9,0,0,0,53,0,0,0,CENPJ;centromere protein J,GO:0005874//microtubule;GO:0005813//centrosome;GO:0008275//gamma-tubulin small complex;GO:0005814//centriole;GO:0005829//cytosol,GO:0007020//microtubule nucleation;GO:0051301//cell division;GO:0046785//microtubule polymerization;GO:0046599//regulation of centriole replication;GO:0000278//mitotic cell cycle;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle,GO:0015631//tubulin binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
55837,0,1,0,1,57,15,19,23,26,0,8,0,EAPP;E2F-associated phosphoprotein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus,GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation,-,-
55839,29,688,394,797,954,22,62,300,77,6,468,0,CENPN;centromere protein N,GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006334//nucleosome assembly;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0034080//CENP-A containing nucleosome assembly,-,-
5584,0,3,0,51,282,0,28,13,57,0,0,1,"PRKCI;protein kinase C, iota",GO:0005829//cytosol;GO:0045171//intercellular bridge;GO:0015630//microtubule cytoskeleton;GO:0043220//Schmidt-Lanterman incisure;GO:0005634//nucleus;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0043234//protein complex;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0061024//membrane organization;GO:0006468//protein phosphorylation;GO:0007015//actin filament organization;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0048194//Golgi vesicle budding;GO:0035089//establishment of apical/basal cell polarity;GO:0060252//positive regulation of glial cell proliferation;GO:0010976//positive regulation of neuron projection development;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0006612//protein targeting to membrane;GO:0042462//eye photoreceptor cell development;GO:0070830//tight junction assembly;GO:0070555//response to interleukin-1;GO:0016477//cell migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0034329//cell junction assembly;GO:0007010//cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0046326//positive regulation of glucose import;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0032869//cellular response to insulin stimulus;GO:0045216//cell-cell junction organization;GO:0046903//secretion;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0034351//negative regulation of glial cell apoptotic process;GO:0016192//vesicle-mediated transport,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005543//phospholipid binding;GO:0019904//protein domain specific binding;GO:0004697//protein kinase C activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity,K06069//Type II diabetes mellitus;Chemokine signaling pathway;Tight junction;Insulin signaling pathway;Endocytosis
55840,0,0,40,7,70,0,0,0,0,0,0,109,EAF2;ELL associated factor 2,GO:0032783//ELL-EAF complex;GO:0016607//nuclear speck;GO:0008023//transcription elongation factor complex,"GO:0006915//apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0030308//negative regulation of cell growth",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding,-
55841,0,0,1,14,57,38,10,0,63,0,10,0,WWC3;WWC family member 3,GO:0005829//cytosol,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046621//negative regulation of organ growth;GO:0035331//negative regulation of hippo signaling,GO:0019900//kinase binding;GO:0032947//protein complex scaffold,K06112//Tight junction;K05631//Tight junction;K07532//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Axon guidance;Tuberculosis
55843,77,0,0,0,0,0,33,0,46,0,9,0,ARHGAP15;Rho GTPase activating protein 15,GO:0005829//cytosol;GO:0016020//membrane,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032855//positive regulation of Rac GTPase activity;GO:0008360//regulation of cell shape,GO:0030675//Rac GTPase activator activity,K13736//Bacterial invasion of epithelial cells;K04450//Dopaminergic synapse;Cocaine addiction;HTLV-I infection;Alcoholism;Influenza A;MAPK signaling pathway;Amphetamine addiction;Epstein-Barr virus infection
55844,38,13,1,0,27,1,0,0,42,0,0,0,"PPP2R2D;protein phosphatase 2, regulatory subunit B, delta",GO:0005737//cytoplasm;GO:0000159//protein phosphatase type 2A complex,GO:0010458//exit from mitosis;GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0008601//protein phosphatase type 2A regulator activity,K04354//Chagas disease (American trypanosomiasis);Dopaminergic synapse;Tight junction;Hepatitis C;mRNA surveillance pathway;Cell cycle - yeast
55845,0,120,0,30,87,21,0,0,22,0,0,0,"BRK1;BRICK1, SCAR/WAVE actin-nucleating complex subunit",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0031209//SCAR complex;GO:0030027//lamellipodium,GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0016601//Rac protein signal transduction;GO:0045087//innate immune response;GO:0001701//in utero embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0010592//positive regulation of lamellipodium assembly;GO:0048870//cell motility;GO:0030036//actin cytoskeleton organization;GO:0070207//protein homotrimerization,GO:0032403//protein complex binding;GO:0048365//Rac GTPase binding,K05752//Regulation of actin cytoskeleton
55846,0,9,0,0,26,11,23,0,13,0,0,0,ITFG2;integrin alpha FG-GAP repeat containing 2,GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0002314//germinal center B cell differentiation,-,-
55847,0,0,0,0,0,32,0,0,0,0,0,0,CISD1;CDGSH iron sulfur domain 1,GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane,GO:0043457//regulation of cellular respiration,"GO:0046872//metal ion binding;GO:0051537//2 iron, 2 sulfur cluster binding",-
55848,53,0,0,0,0,0,0,0,0,0,0,0,"PLGRKT;plasminogen receptor, C-terminal lysine transmembrane protein",GO:0005739//mitochondrion;GO:0005887//integral component of plasma membrane,GO:0006954//inflammatory response;GO:0010756//positive regulation of plasminogen activation;GO:0006935//chemotaxis,-,-
5585,37,0,1,0,14,1,2,5,8,1,0,0,PKN1;protein kinase N1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0016023//cytoplasmic membrane-bounded vesicle,"GO:0035407//histone H3-T11 phosphorylation;GO:2000145//regulation of cell motility;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0007257//activation of JUN kinase activity;GO:0006972//hyperosmotic response;GO:0006351//transcription, DNA-templated;GO:0010631//epithelial cell migration;GO:0006468//protein phosphorylation",GO:0005080//protein kinase C binding;GO:0017049//GTP-Rho binding;GO:0050681//androgen receptor binding;GO:0042826//histone deacetylase binding;GO:0004672//protein kinase activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0048365//Rac GTPase binding;GO:0035402//histone kinase activity (H3-T11 specific);GO:0004697//protein kinase C activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0042393//histone binding,K06071//Salmonella infection
55850,0,0,0,0,0,0,0,0,21,0,0,257,USE1;unconventional SNARE in the ER 1 homolog (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005764//lysosome,GO:0030163//protein catabolic process;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0007041//lysosomal transport;GO:0015031//protein transport;GO:0060628//regulation of ER to Golgi vesicle-mediated transport;GO:0071786//endoplasmic reticulum tubular network organization;GO:0032940//secretion by cell,GO:0005515//protein binding,K08507//SNARE interactions in vesicular transport
55851,0,0,0,0,5,0,0,0,0,0,0,0,PSENEN;presenilin enhancer gamma secretase subunit,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0032580//Golgi cisterna membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0007219//Notch signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016485//protein processing;GO:0007220//Notch receptor processing;GO:0031293//membrane protein intracellular domain proteolysis;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0006509//membrane protein ectodomain proteolysis;GO:0043085//positive regulation of catalytic activity;GO:0042987//amyloid precursor protein catabolic process,GO:0005515//protein binding,K06170//Notch signaling pathway;Alzheimer's disease
55852,3,0,0,26,13,4,0,0,56,132,16,0,TEX2;testis expressed 2,GO:0016021//integral component of membrane,GO:0006665//sphingolipid metabolic process;GO:0007165//signal transduction,-,-
55854,0,52,1,79,264,0,0,0,22,0,0,0,ZC3H15;zinc finger CCCH-type containing 15,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0019221//cytokine-mediated signaling pathway,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
55855,107,0,0,0,2,11,0,0,0,0,0,0,"FAM45B;family with sequence similarity 45, member A pseudogene",-,-,-,-
55856,0,321,219,472,922,31,46,0,40,0,582,0,ACOT13;acyl-CoA thioesterase 13,GO:0005819//spindle;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process;GO:0051289//protein homotetramerization,GO:0047617//acyl-CoA hydrolase activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
55857,0,5,0,0,0,0,0,0,9,0,0,0,KIZ;kizuna centrosomal protein,GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0007051//spindle organization,GO:0019901//protein kinase binding;GO:0005515//protein binding,-
55858,0,0,0,0,18,0,0,50,51,0,0,0,TMEM165;transmembrane protein 165,GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005765//lysosomal membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane;GO:0032588//trans-Golgi network membrane;GO:0031902//late endosome membrane,GO:0006487//protein N-linked glycosylation;GO:0032472//Golgi calcium ion transport;GO:0035751//regulation of lysosomal lumen pH;GO:0006874//cellular calcium ion homeostasis,-,-
55859,0,0,0,0,0,0,0,0,14,0,0,0,"BEX1;brain expressed, X-linked 1",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex,GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0001102//RNA polymerase II activating transcription factor binding,K12465//Neurotrophin signaling pathway
5586,75,0,0,0,20,28,1,0,52,0,0,1,PKN2;protein kinase N2,GO:0005634//nucleus;GO:0043296//apical junction complex;GO:0030496//midbody;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0032154//cleavage furrow;GO:0016020//membrane,"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0043297//apical junction assembly;GO:0010631//epithelial cell migration;GO:0007155//cell adhesion;GO:0032467//positive regulation of cytokinesis;GO:0051301//cell division;GO:0045931//positive regulation of mitotic cell cycle;GO:0007049//cell cycle;GO:0007165//signal transduction;GO:2000145//regulation of cell motility;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0042826//histone deacetylase binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0004697//protein kinase C activity,K06071//Salmonella infection
55860,0,0,0,1,22,0,11,0,0,0,0,0,ACTR10;actin-related protein 10 homolog (S. cerevisiae),GO:0005737//cytoplasm;GO:0005869//dynactin complex,GO:0007018//microtubule-based movement,-,K05692//Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Viral myocarditis;Adherens junction;Phototransduction - fly;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A
55862,2,0,1,11,1,0,0,0,12,0,0,0,ECHDC1;enoyl CoA hydratase domain containing 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0016831//carboxy-lyase activity;GO:0004492//methylmalonyl-CoA decarboxylase activity,"K05607//Metabolic pathways;Valine, leucine and isoleucine degradation"
55863,9,0,0,1,52,0,0,0,26,0,0,0,TMEM126B;transmembrane protein 126B,GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane,-,-,-
55867,167,0,0,0,4,22,0,50,6,174,0,0,"SLC22A11;solute carrier family 22 (organic anion/urate transporter), member 11",GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane,GO:0046415//urate metabolic process;GO:0015711//organic anion transport;GO:0055085//transmembrane transport,GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity,-
55869,0,1,0,32,32,10,0,0,0,0,9,0,HDAC8;histone deacetylase 8,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000228//nuclear chromosome;GO:0000118//histone deacetylase complex;GO:0005829//cytosol,"GO:0006333//chromatin assembly or disassembly;GO:0007062//sister chromatid cohesion;GO:0070933//histone H4 deacetylation;GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070932//histone H3 deacetylation;GO:0071922//regulation of cohesin localization to chromatin;GO:0016568//chromatin modification",GO:0004407//histone deacetylase activity;GO:0008134//transcription factor binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0046872//metal ion binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific),K11405//Alcoholism
5587,0,65,1,53,207,0,33,47,22,0,15,0,PRKD1;protein kinase D1,GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network;GO:0005886//plasma membrane,GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007030//Golgi organization;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0006915//apoptotic process;GO:0007229//integrin-mediated signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0007165//signal transduction;GO:0045806//negative regulation of endocytosis;GO:0010976//positive regulation of neuron projection development;GO:0046777//protein autophosphorylation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001938//positive regulation of endothelial cell proliferation;GO:0044281//small molecule metabolic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045766//positive regulation of angiogenesis;GO:0032793//positive regulation of CREB transcription factor activity;GO:0060548//negative regulation of cell death;GO:0006665//sphingolipid metabolic process;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0034599//cellular response to oxidative stress;GO:1901727//positive regulation of histone deacetylase activity;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:2001044//regulation of integrin-mediated signaling pathway;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0008283//cell proliferation;GO:0010837//regulation of keratinocyte proliferation;GO:0048193//Golgi vesicle transport;GO:0030148//sphingolipid biosynthetic process;GO:0001525//angiogenesis;GO:0045087//innate immune response,GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0004674//protein serine/threonine kinase activity,-
55870,74,78,1,91,313,75,33,158,102,0,4,0,"ASH1L;ash1 (absent, small, or homeotic)-like (Drosophila)",GO:0005694//chromosome;GO:0005923//tight junction;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006366//transcription from RNA polymerase II promoter;GO:0034968//histone lysine methylation;GO:0007267//cell-cell signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0006323//DNA packaging",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003682//chromatin binding,K06101//Lysine degradation;Tight junction
55871,0,2,0,19,45,0,0,0,4,0,0,0,CBWD1;COBW domain containing 1,-,-,GO:0005524//ATP binding,-
55876,0,0,0,0,0,0,8,0,22,0,3,0,GSDMB;gasdermin B,GO:0005737//cytoplasm,-,-,-
55879,0,0,0,0,0,0,0,0,32,0,16,0,"GABRQ;gamma-aminobutyric acid (GABA) A receptor, theta",GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex,GO:0006836//neurotransmitter transport;GO:0007165//signal transduction;GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity;GO:0005326//neurotransmitter transporter activity;GO:0005230//extracellular ligand-gated ion channel activity;GO:0004888//transmembrane signaling receptor activity;GO:0004890//GABA-A receptor activity,K05192//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
5588,86,0,0,0,0,0,2,0,123,0,26,0,"PRKCQ;protein kinase C, theta",GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0001772//immunological synapse,"GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination;GO:0007411//axon guidance;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light;GO:0070233//negative regulation of T cell apoptotic process;GO:0006509//membrane protein ectodomain proteolysis;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006355//regulation of transcription, DNA-templated;GO:0045087//innate immune response;GO:0050870//positive regulation of T cell activation;GO:0032753//positive regulation of interleukin-4 production;GO:2000570//positive regulation of T-helper 2 cell activation;GO:0001558//regulation of cell growth;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0050852//T cell receptor signaling pathway;GO:0090330//regulation of platelet aggregation;GO:0007596//blood coagulation;GO:0016056//rhodopsin mediated signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0006915//apoptotic process;GO:0030168//platelet activation;GO:2000318//positive regulation of T-helper 17 type immune response;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0006954//inflammatory response;GO:0032740//positive regulation of interleukin-17 production",GO:0005524//ATP binding;GO:0004697//protein kinase C activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity,K06068//Fc gamma R-mediated phagocytosis;Tight junction;Chemokine signaling pathway;GnRH signaling pathway;Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;Measles;Type II diabetes mellitus;T cell receptor signaling pathway;Adipocytokine signaling pathway;Neurotrophin signaling pathway;Vascular smooth muscle contraction
55884,0,22,0,45,187,0,21,23,32,0,12,623,WSB2;WD repeat and SOCS box containing 2,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,-,-
55885,0,0,0,0,0,4,0,58,59,0,5,0,LMO3;LIM domain only 3 (rhombotin-like 2),-,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding,K15612//Transcriptional misregulation in cancer
55888,0,37,0,8,13,46,0,59,28,0,0,0,ZKSCAN7;zinc finger with KRAB and SCAN domains 7,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
55889,0,0,0,0,0,14,53,15,0,0,0,0,"GOLGA6B;golgin A6 family, member B",GO:0005794//Golgi apparatus,-,-,K12478//Phagosome;Endocytosis;Tuberculosis;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
5589,0,0,1,0,46,0,38,47,43,0,0,0,PRKCSH;protein kinase C substrate 80K-H,GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005622//intracellular,GO:0045087//innate immune response;GO:0006491//N-glycan processing;GO:0001701//in utero embryonic development;GO:0072001//renal system development;GO:0043687//post-translational protein modification;GO:0006807//nitrogen compound metabolic process;GO:0010977//negative regulation of neuron projection development;GO:0018279//protein N-linked glycosylation via asparagine;GO:0001889//liver development;GO:0006457//protein folding;GO:0051291//protein heterooligomerization;GO:0035556//intracellular signal transduction;GO:0044267//cellular protein metabolic process,GO:0044325//ion channel binding;GO:0005509//calcium ion binding;GO:0051219//phosphoprotein binding;GO:0005080//protein kinase C binding;GO:0003723//RNA binding,K08288//Protein processing in endoplasmic reticulum
55890,0,0,0,0,0,33,0,0,23,0,0,0,"GPRC5C;G protein-coupled receptor, class C, group 5, member C",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0031982//vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
55892,0,2,0,14,4,0,19,0,31,70,0,0,MYNN;myoneurin,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K10500//Transcriptional misregulation in cancer;Cell cycle
55893,0,0,0,10,59,0,0,0,27,0,0,0,ZNF395;zinc finger protein 395,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
55897,83,0,0,0,0,0,0,45,1,0,0,0,MESP1;mesoderm posterior basic helix-loop-helix transcription factor 1,GO:0005634//nucleus,"GO:0003259//cardioblast anterior-lateral migration;GO:0060913//cardiac cell fate determination;GO:0060975//cardioblast migration to the midline involved in heart field formation;GO:0023019//signal transduction involved in regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0003143//embryonic heart tube morphogenesis;GO:0008078//mesodermal cell migration;GO:0003236//sinus venosus morphogenesis;GO:0003210//cardiac atrium formation;GO:0001947//heart looping;GO:0042664//negative regulation of endodermal cell fate specification;GO:0045446//endothelial cell differentiation;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035481//positive regulation of Notch signaling pathway involved in heart induction;GO:0045747//positive regulation of Notch signaling pathway;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0090082//positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060921//sinoatrial node cell differentiation;GO:0055007//cardiac muscle cell differentiation;GO:0048368//lateral mesoderm development;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0003241//growth involved in heart morphogenesis;GO:0003139//secondary heart field specification;GO:0007219//Notch signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0022008//neurogenesis;GO:0070368//positive regulation of hepatocyte differentiation;GO:0003211//cardiac ventricle formation;GO:0007369//gastrulation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046983//protein dimerization activity;GO:0035326//enhancer binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
55898,0,37,0,0,22,17,0,49,60,0,40,0,UNC45A;unc-45 homolog A (C. elegans),GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0007517//muscle organ development;GO:0061077//chaperone-mediated protein folding;GO:0030154//cell differentiation,GO:0051879//Hsp90 protein binding,K04460//MAPK signaling pathway;K09561//Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum;K09553//Prion diseases
5590,59,81,117,1,77,27,26,0,16,0,197,0,"PRKCZ;protein kinase C, zeta",GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0043203//axon hillock;GO:0043234//protein complex;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005923//tight junction;GO:0005815//microtubule organizing center;GO:0016363//nuclear matrix;GO:0035748//myelin sheath abaxonal region;GO:0005635//nuclear envelope;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0005768//endosome;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0045179//apical cortex,GO:0006954//inflammatory response;GO:0007616//long-term memory;GO:0018105//peptidyl-serine phosphorylation;GO:0007165//signal transduction;GO:0031584//activation of phospholipase D activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2001181//positive regulation of interleukin-10 secretion;GO:2000664//positive regulation of interleukin-5 secretion;GO:0006468//protein phosphorylation;GO:0051291//protein heterooligomerization;GO:0030010//establishment of cell polarity;GO:0032753//positive regulation of interleukin-4 production;GO:0051346//negative regulation of hydrolase activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0070528//protein kinase C signaling;GO:0072659//protein localization to plasma membrane;GO:0046628//positive regulation of insulin receptor signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:2000667//positive regulation of interleukin-13 secretion;GO:0016477//cell migration;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0032148//activation of protein kinase B activity;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0060291//long-term synaptic potentiation;GO:0047496//vesicle transport along microtubule;GO:0000226//microtubule cytoskeleton organization;GO:0008286//insulin receptor signaling pathway;GO:0060081//membrane hyperpolarization;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0046326//positive regulation of glucose import;GO:0001954//positive regulation of cell-matrix adhesion;GO:0031333//negative regulation of protein complex assembly;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:1990138//neuron projection extension;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0071889//14-3-3 protein binding;GO:0043560//insulin receptor substrate binding;GO:0015459//potassium channel regulator activity;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0019904//protein domain specific binding;GO:0004697//protein kinase C activity;GO:0005524//ATP binding;GO:0043274//phospholipase binding,K06069//Type II diabetes mellitus;Endocytosis;Insulin signaling pathway;Tight junction;Chemokine signaling pathway
55900,0,0,0,11,60,26,47,0,10,0,0,0,ZNF302;zinc finger protein 302,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
55901,0,0,0,0,0,0,1,0,36,253,0,0,"THSD1;thrombospondin, type I, domain containing 1",GO:0005737//cytoplasm;GO:0071944//cell periphery;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005576//extracellular region,GO:0002244//hematopoietic progenitor cell differentiation,-,K06841//Axon guidance
55902,65,0,45,11,50,0,1,0,46,0,0,0,ACSS2;acyl-CoA synthetase short-chain family member 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus,GO:0006069//ethanol oxidation;GO:0019542//propionate biosynthetic process;GO:0008610//lipid biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0019427//acetyl-CoA biosynthetic process from acetate;GO:0019413//acetate biosynthetic process,GO:0005524//ATP binding;GO:0016208//AMP binding;GO:0003987//acetate-CoA ligase activity,K01895//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Methane metabolism;Microbial metabolism in diverse environments;Carbon fixation pathways in prokaryotes;Pyruvate metabolism;Propanoate metabolism;Metabolic pathways;Two-component system
55904,210,1,0,101,398,14,0,1,64,238,82,0,KMT2E;lysine (K)-specific methyltransferase 2E,GO:0070688//MLL5-L complex;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005886//plasma membrane,"GO:0051568//histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0071300//cellular response to retinoic acid;GO:0042119//neutrophil activation;GO:0048384//retinoic acid receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030854//positive regulation of granulocyte differentiation;GO:0030218//erythrocyte differentiation;GO:0006306//DNA methylation;GO:0002446//neutrophil mediated immunity;GO:0007050//cell cycle arrest",GO:0019899//enzyme binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K09189//Lysine degradation
55905,121,24,0,41,134,1,17,0,36,0,0,0,RNF114;ring finger protein 114,GO:0005622//intracellular;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0016567//protein ubiquitination;GO:0007283//spermatogenesis;GO:0030154//cell differentiation,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
55906,38,0,0,0,11,0,0,36,39,0,0,0,"ZC4H2;zinc finger, C4H2 domain containing",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,GO:0021522//spinal cord motor neuron differentiation;GO:0007528//neuromuscular junction development;GO:0007399//nervous system development,GO:0046872//metal ion binding,-
55907,88,59,3,29,72,10,0,0,17,0,13,0,CMAS;cytidine monophosphate N-acetylneuraminic acid synthetase,GO:0005634//nucleus;GO:0016020//membrane,GO:0006054//N-acetylneuraminate metabolic process;GO:0009103//lipopolysaccharide biosynthetic process,GO:0008781//N-acylneuraminate cytidylyltransferase activity,K00983//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
55908,0,0,0,0,0,12,0,0,26,0,0,0,C19orf80;chromosome 19 open reading frame 80,GO:0005576//extracellular region,GO:0044342//type B pancreatic cell proliferation;GO:0070328//triglyceride homeostasis;GO:0006006//glucose metabolic process;GO:0010954//positive regulation of protein processing;GO:0050746//regulation of lipoprotein metabolic process;GO:0044255//cellular lipid metabolic process,GO:0005179//hormone activity;GO:0005515//protein binding,-
55909,0,1,0,0,5,0,0,0,31,355,30,0,BIN3;bridging integrator 3,GO:0005884//actin filament;GO:0005737//cytoplasm,GO:0010591//regulation of lamellipodium assembly;GO:0009826//unidimensional cell growth;GO:0000910//cytokinesis;GO:0008104//protein localization;GO:0000917//barrier septum assembly;GO:0048741//skeletal muscle fiber development;GO:0007015//actin filament organization,GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity,K12562//Fc gamma R-mediated phagocytosis
5591,83,67,3,57,305,51,20,82,152,221,14,0,"PRKDC;protein kinase, DNA-activated, catalytic polypeptide",GO:0016020//membrane;GO:0070419//nonhomologous end joining complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0005634//nucleus;GO:0005667//transcription factor complex,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0018105//peptidyl-serine phosphorylation;GO:0002328//pro-B cell differentiation;GO:0042752//regulation of circadian rhythm;GO:0002360//T cell lineage commitment;GO:0043065//positive regulation of apoptotic process;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0035234//ectopic germ cell programmed cell death;GO:0033077//T cell differentiation in thymus;GO:0031648//protein destabilization;GO:0006464//cellular protein modification process;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0002326//B cell lineage commitment;GO:0007507//heart development;GO:0072431//signal transduction involved in mitotic G1 DNA damage checkpoint;GO:0033153//T cell receptor V(D)J recombination;GO:0001756//somitogenesis;GO:0032869//cellular response to insulin stimulus;GO:0010332//response to gamma radiation;GO:0001933//negative regulation of protein phosphorylation;GO:0000723//telomere maintenance;GO:0007420//brain development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0033152//immunoglobulin V(D)J recombination,GO:0008134//transcription factor binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004677//DNA-dependent protein kinase activity;GO:0019899//enzyme binding,K06642//Cell cycle;Non-homologous end-joining
55911,0,0,0,0,0,0,15,38,9,0,0,0,APOBR;apolipoprotein B receptor,GO:0005886//plasma membrane;GO:0034361//very-low-density lipoprotein particle;GO:0016020//membrane;GO:0034362//low-density lipoprotein particle;GO:0042627//chylomicron,GO:0006898//receptor-mediated endocytosis;GO:0006641//triglyceride metabolic process;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process,GO:0030229//very-low-density lipoprotein particle receptor activity,-
55914,93,136,1,110,284,17,66,0,46,32,0,0,ERBB2IP;erbb2 interacting protein,GO:0005886//plasma membrane;GO:0005604//basement membrane;GO:0030056//hemidesmosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0009925//basal plasma membrane;GO:0031965//nuclear membrane,GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0007155//cell adhesion;GO:0045175//basal protein localization;GO:0016049//cell growth;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0007049//cell cycle;GO:0007229//integrin-mediated signaling pathway;GO:0045104//intermediate filament cytoskeleton organization,GO:0005200//structural constituent of cytoskeleton;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005176//ErbB-2 class receptor binding,K12796//NOD-like receptor signaling pathway
55915,0,46,1,11,34,0,1,1,45,0,7,0,LANCL2;LanC lantibiotic synthetase component C-like 2 (bacterial),GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0030864//cortical actin cytoskeleton;GO:0005737//cytoplasm,"GO:0008152//metabolic process;GO:0009789//positive regulation of abscisic acid-activated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated",GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005524//ATP binding;GO:0003824//catalytic activity;GO:0005525//GTP binding,-
55916,0,0,0,11,59,2,35,0,16,0,0,0,NXT2;nuclear transport factor 2-like export factor 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051028//mRNA transport;GO:0015031//protein transport,-,K14285//mRNA surveillance pathway;RNA transport;Influenza A;Ribosome biogenesis in eukaryotes
55917,0,0,0,9,28,7,0,0,59,0,0,0,CTTNBP2NL;CTTNBP2 N-terminal like,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton,GO:0032410//negative regulation of transporter activity;GO:0006470//protein dephosphorylation,GO:0051721//protein phosphatase 2A binding;GO:0005515//protein binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
5592,91,0,0,0,0,26,0,0,42,0,0,0,"PRKG1;protein kinase, cGMP-dependent, type I",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0006468//protein phosphorylation;GO:0030900//forebrain development;GO:0030036//actin cytoskeleton organization;GO:0043087//regulation of GTPase activity;GO:0060087//relaxation of vascular smooth muscle;GO:0007596//blood coagulation;GO:0001764//neuron migration;GO:0016358//dendrite development;GO:0007165//signal transduction;GO:0090331//negative regulation of platelet aggregation;GO:0019934//cGMP-mediated signaling,GO:0005515//protein binding;GO:0030553//cGMP binding;GO:0004692//cGMP-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005246//calcium channel regulator activity,K07376//Gap junction;Vascular smooth muscle contraction;Long-term depression;Olfactory transduction;Salivary secretion
55920,0,37,0,18,43,17,0,0,29,21,0,222,RCC2;regulator of chromosome condensation 2,"GO:0005829//cytosol;GO:0005730//nucleolus;GO:0030496//midbody;GO:0005874//microtubule;GO:1990023//mitotic spindle midzone;GO:0034506//chromosome, centromeric core domain",GO:0034260//negative regulation of GTPase activity;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0000278//mitotic cell cycle;GO:0048041//focal adhesion assembly;GO:0072356//chromosome passenger complex localization to kinetochore;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore;GO:0051895//negative regulation of focal adhesion assembly;GO:0030334//regulation of cell migration;GO:0007032//endosome organization;GO:0007229//integrin-mediated signaling pathway;GO:0007067//mitotic nuclear division,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0048365//Rac GTPase binding,K10595//Ubiquitin mediated proteolysis
55922,0,39,0,7,8,22,24,0,28,0,12,0,NKRF;NFKB repressing factor,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
55924,0,0,96,10,17,0,23,0,0,0,12,0,"FAM212B;family with sequence similarity 212, member B",-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
55929,0,0,0,3,0,0,0,53,11,0,0,0,DMAP1;DNA methyltransferase 1 associated protein 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005657//replication fork;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex,"GO:0006338//chromatin remodeling;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated;GO:0043968//histone H2A acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0043967//histone H4 acetylation;GO:0006306//DNA methylation;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0006281//DNA repair",GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0005515//protein binding,-
5593,0,22,1,20,161,0,27,0,58,0,0,0,"PRKG2;protein kinase, cGMP-dependent, type II",GO:0016324//apical plasma membrane;GO:0005829//cytosol,GO:0046209//nitric oxide metabolic process;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0006468//protein phosphorylation;GO:0050999//regulation of nitric-oxide synthase activity;GO:0007596//blood coagulation;GO:0032922//circadian regulation of gene expression,GO:0004672//protein kinase activity;GO:0030553//cGMP binding;GO:0004692//cGMP-dependent protein kinase activity;GO:0005524//ATP binding,K07376//Salivary secretion;Olfactory transduction;Vascular smooth muscle contraction;Long-term depression;Gap junction
55930,74,1,37,50,167,66,14,1,138,0,0,366,MYO5C;myosin VC,GO:0016459//myosin complex;GO:0070062//extracellular vesicular exosome,GO:0008152//metabolic process,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0003774//motor activity,-
5594,0,42,0,101,168,14,15,0,22,0,24,0,MAPK1;mitogen-activated protein kinase 1,GO:0043234//protein complex;GO:0005770//late endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0032839//dendrite cytoplasm;GO:0005815//microtubule organizing center;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0070062//extracellular vesicular exosome;GO:0072686//mitotic spindle;GO:0015630//microtubule cytoskeleton;GO:0005901//caveola;GO:0005634//nucleus;GO:0031143//pseudopodium;GO:0005730//nucleolus;GO:0043204//perikaryon;GO:0005925//focal adhesion,"GO:0007411//axon guidance;GO:0051403//stress-activated MAPK cascade;GO:0031647//regulation of protein stability;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0000189//MAPK import into nucleus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0034134//toll-like receptor 2 signaling pathway;GO:0045596//negative regulation of cell differentiation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0033598//mammary gland epithelial cell proliferation;GO:0043330//response to exogenous dsRNA;GO:0038127//ERBB signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0070849//response to epidermal growth factor;GO:0007265//Ras protein signal transduction;GO:0007049//cell cycle;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009636//response to toxic substance;GO:0006935//chemotaxis;GO:0032872//regulation of stress-activated MAPK cascade;GO:0019858//cytosine metabolic process;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006950//response to stress;GO:0072584//caveolin-mediated endocytosis;GO:0018107//peptidyl-threonine phosphorylation;GO:0008286//insulin receptor signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0019233//sensory perception of pain;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0030168//platelet activation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0030335//positive regulation of cell migration;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0050853//B cell receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006915//apoptotic process;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:0043627//response to estrogen;GO:0007268//synaptic transmission;GO:0045727//positive regulation of translation;GO:0006974//cellular response to DNA damage stimulus;GO:2000641//regulation of early endosome to late endosome transport;GO:0007165//signal transduction;GO:0060716//labyrinthine layer blood vessel development;GO:0000186//activation of MAPKK activity;GO:0006351//transcription, DNA-templated;GO:0009887//organ morphogenesis;GO:0034146//toll-like receptor 5 signaling pathway;GO:0051493//regulation of cytoskeleton organization;GO:0045087//innate immune response;GO:0007264//small GTPase mediated signal transduction;GO:0007596//blood coagulation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0090170//regulation of Golgi inheritance;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0031663//lipopolysaccharide-mediated signaling pathway",GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0001784//phosphotyrosine binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0019902//phosphatase binding;GO:0008134//transcription factor binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0004707//MAP kinase activity,K04371//Acute myeloid leukemia;Cholinergic synapse;TGF-beta signaling pathway;Melanoma;Regulation of actin cytoskeleton;Hepatitis C;Tuberculosis;Prostate cancer;Aldosterone-regulated sodium reabsorption;Long-term potentiation;Glutamatergic synapse;Chronic myeloid leukemia;Vascular smooth muscle contraction;Type II diabetes mellitus;Colorectal cancer;Long-term depression;Retrograde endocannabinoid signaling;Endometrial cancer;MAPK signaling pathway - fly;Leishmaniasis;Glioma;Thyroid cancer;Pathways in cancer;GnRH signaling pathway;Serotonergic synapse;Toll-like receptor signaling pathway;Influenza A;Oocyte meiosis;ErbB signaling pathway;Bladder cancer;Renal cell carcinoma;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Non-small cell lung cancer;Neurotrophin signaling pathway;Dorso-ventral axis formation;Cell cycle - yeast;Melanogenesis;Axon guidance;MAPK signaling pathway - yeast;Salmonella infection;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Fc gamma R-mediated phagocytosis;Shigellosis;NOD-like receptor signaling pathway;Osteoclast differentiation;Toxoplasmosis;Prion diseases;Alzheimer's disease;VEGF signaling pathway;Focal adhesion;Gap junction;Chemokine signaling pathway;Pancreatic cancer;Pertussis;Alcoholism;MAPK signaling pathway;mTOR signaling pathway;Adherens junction;Plant-pathogen interaction
5595,0,13,0,0,23,0,0,0,1,0,0,0,MAPK3;mitogen-activated protein kinase 3,GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0031143//pseudopodium;GO:0005634//nucleus;GO:0005901//caveola;GO:0015630//microtubule cytoskeleton;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005770//late endosome;GO:0005856//cytoskeleton;GO:0005654//nucleoplasm,GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0019233//sensory perception of pain;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0090170//regulation of Golgi inheritance;GO:0016032//viral process;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0030168//platelet activation;GO:0032872//regulation of stress-activated MAPK cascade;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007596//blood coagulation;GO:0034162//toll-like receptor 9 signaling pathway;GO:0072584//caveolin-mediated endocytosis;GO:0008286//insulin receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0070849//response to epidermal growth factor;GO:0007264//small GTPase mediated signal transduction;GO:0051493//regulation of cytoskeleton organization;GO:0045087//innate immune response;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007049//cell cycle;GO:0034138//toll-like receptor 3 signaling pathway;GO:0051216//cartilage development;GO:0007265//Ras protein signal transduction;GO:0043330//response to exogenous dsRNA;GO:0035066//positive regulation of histone acetylation;GO:0000186//activation of MAPKK activity;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010467//gene expression;GO:0030509//BMP signaling pathway;GO:0009887//organ morphogenesis;GO:0016310//phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000641//regulation of early endosome to late endosome transport;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0033129//positive regulation of histone phosphorylation;GO:0006915//apoptotic process;GO:0006975//DNA damage induced protein phosphorylation;GO:0071260//cellular response to mechanical stimulus;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:2000657//negative regulation of apolipoprotein binding;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0034134//toll-like receptor 2 signaling pathway;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0007411//axon guidance;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade,GO:0019902//phosphatase binding;GO:0004707//MAP kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0001784//phosphotyrosine binding,K04371//Cholinergic synapse;Acute myeloid leukemia;TGF-beta signaling pathway;Melanoma;Hepatitis C;Regulation of actin cytoskeleton;Aldosterone-regulated sodium reabsorption;Prostate cancer;Tuberculosis;Long-term potentiation;Glutamatergic synapse;Vascular smooth muscle contraction;Chronic myeloid leukemia;Colorectal cancer;Type II diabetes mellitus;Long-term depression;Retrograde endocannabinoid signaling;MAPK signaling pathway - fly;Leishmaniasis;Endometrial cancer;Glioma;Thyroid cancer;Pathways in cancer;GnRH signaling pathway;Serotonergic synapse;Influenza A;Toll-like receptor signaling pathway;Oocyte meiosis;Bladder cancer;ErbB signaling pathway;Renal cell carcinoma;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Non-small cell lung cancer;Neurotrophin signaling pathway;Dorso-ventral axis formation;Cell cycle - yeast;Melanogenesis;Axon guidance;MAPK signaling pathway - yeast;Insulin signaling pathway;Salmonella infection;Progesterone-mediated oocyte maturation;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Fc gamma R-mediated phagocytosis;NOD-like receptor signaling pathway;Shigellosis;Prion diseases;Osteoclast differentiation;Toxoplasmosis;Alzheimer's disease;Focal adhesion;VEGF signaling pathway;Chemokine signaling pathway;Gap junction;Pancreatic cancer;Alcoholism;Pertussis;MAPK signaling pathway;mTOR signaling pathway;Adherens junction;Plant-pathogen interaction
55954,0,0,0,0,11,0,0,35,9,0,0,0,"ZMAT5;zinc finger, matrin-type 5",GO:0005634//nucleus;GO:0005689//U12-type spliceosomal complex;GO:0005730//nucleolus,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0008270//zinc ion binding,-
55957,0,0,0,0,5,0,0,0,0,57,0,0,LIN37;lin-37 homolog (C. elegans),GO:0017053//transcriptional repressor complex;GO:0005654//nucleoplasm,GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,-
55958,22,74,0,23,66,0,0,0,26,0,0,0,KLHL9;kelch-like family member 9,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0030496//midbody,GO:0016567//protein ubiquitination;GO:0007067//mitotic nuclear division;GO:0000910//cytokinesis,GO:0004842//ubiquitin-protein transferase activity,K10447//Ubiquitin mediated proteolysis
55959,140,0,0,0,0,14,38,0,45,123,1,0,SULF2;sulfatase 2,GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0005795//Golgi stack;GO:0005886//plasma membrane,GO:0014846//esophagus smooth muscle contraction;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0060384//innervation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0030177//positive regulation of Wnt signaling pathway;GO:0030201//heparan sulfate proteoglycan metabolic process;GO:0002063//chondrocyte development;GO:0060348//bone development;GO:0003094//glomerular filtration;GO:0032836//glomerular basement membrane development;GO:0048706//embryonic skeletal system development;GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0001822//kidney development;GO:0051216//cartilage development,GO:0004065//arylsulfatase activity;GO:0005509//calcium ion binding;GO:0008449//N-acetylglucosamine-6-sulfatase activity,-
5596,83,0,0,0,0,0,0,48,22,0,0,0,MAPK4;mitogen-activated protein kinase 4,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000165//MAPK cascade;GO:0006468//protein phosphorylation;GO:0007049//cell cycle,GO:0004707//MAP kinase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0005524//ATP binding,-
55964,0,0,55,1,0,0,20,0,47,0,2,0,SEPT3;septin 3,GO:0030054//cell junction;GO:0045202//synapse;GO:0031105//septin complex,GO:0007049//cell cycle;GO:0051301//cell division,GO:0005525//GTP binding,K04557//Parkinson's disease
55966,0,0,0,0,0,18,34,41,34,0,0,0,AJAP1;adherens junctions associated protein 1,GO:0005912//adherens junction;GO:0016324//apical plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,-
55967,0,0,0,1,0,0,0,0,10,0,0,0,"NDUFA12;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12",GO:0005743//mitochondrial inner membrane;GO:0005747//mitochondrial respiratory chain complex I;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0022904//respiratory electron transport chain;GO:0007585//respiratory gaseous exchange;GO:0006979//response to oxidative stress;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process,GO:0009055//electron carrier activity;GO:0008137//NADH dehydrogenase (ubiquinone) activity,K11352//Metabolic pathways;Huntington's disease;Oxidative phosphorylation;Parkinson's disease;Alzheimer's disease
55968,0,0,0,4,0,0,29,0,4,0,0,0,NSFL1C;NSFL1 (p97) cofactor (p47),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005694//chromosome;GO:0005795//Golgi stack;GO:0045111//intermediate filament cytoskeleton;GO:0005886//plasma membrane;GO:0005730//nucleolus,-,GO:0008289//lipid binding;GO:0005515//protein binding,K14012//Protein processing in endoplasmic reticulum
55969,0,0,0,0,0,6,0,0,0,0,0,0,C20orf24;chromosome 20 open reading frame 24,-,-,-,-
5597,75,32,0,33,175,33,0,0,61,0,0,0,MAPK6;mitogen-activated protein kinase 6,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0007049//cell cycle;GO:0000165//MAPK cascade,GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0005524//ATP binding,-
55970,40,22,1,26,108,14,20,0,45,40,9,0,"GNG12;guanine nucleotide binding protein (G protein), gamma 12",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005834//heterotrimeric G-protein complex,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0006112//energy reserve metabolic process;GO:0021987//cerebral cortex development;GO:0032496//response to lipopolysaccharide;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0071377//cellular response to glucagon stimulus,GO:0042301//phosphate ion binding;GO:0004871//signal transducer activity;GO:0030165//PDZ domain binding,K04347//Morphine addiction;Regulation of actin cytoskeleton;MAPK signaling pathway;Glutamatergic synapse;Serotonergic synapse;Alcoholism;Retrograde endocannabinoid signaling;Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway
55971,0,40,0,53,8,14,0,0,42,59,21,0,BAIAP2L1;BAI1-associated protein 2-like 1,GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030838//positive regulation of actin filament polymerization;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0009617//response to bacterium;GO:0007165//signal transduction;GO:0046847//filopodium assembly,GO:0017124//SH3 domain binding;GO:0008093//cytoskeletal adaptor activity;GO:0070064//proline-rich region binding;GO:0003779//actin binding,K05627//Adherens junction;Regulation of actin cytoskeleton
55972,0,0,1,0,20,12,0,0,0,0,10,0,"SLC25A40;solute carrier family 25, member 40",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport,-,-
55973,0,26,0,0,2,14,0,0,16,0,0,0,BCAP29;B-cell receptor-associated protein 29,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006886//intracellular protein transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006915//apoptotic process;GO:0001649//osteoblast differentiation,-,K14009//Protein processing in endoplasmic reticulum
55974,62,0,2,3,28,2,8,0,24,0,0,0,"SLC50A1;solute carrier family 50 (sugar efflux transporter), member 1",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005634//nucleus,"GO:0006310//DNA recombination;GO:0042946//glucoside transport;GO:0008643//carbohydrate transport;GO:0045815//positive regulation of gene expression, epigenetic",GO:0042947//glucoside transmembrane transporter activity,-
55975,0,0,0,11,16,0,37,1,34,0,0,0,KLHL7;kelch-like family member 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0016567//protein ubiquitination,GO:0042803//protein homodimerization activity,-
5598,0,0,0,0,0,16,0,2,10,0,0,0,MAPK7;mitogen-activated protein kinase 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0005730//nucleolus;GO:0005829//cytosol,GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0071499//cellular response to laminar fluid shear stress;GO:0036003//positive regulation of transcription from RNA polymerase II promoter in response to stress;GO:0051247//positive regulation of protein metabolic process;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0034162//toll-like receptor 9 signaling pathway;GO:0030821//negative regulation of cAMP catabolic process;GO:0045087//innate immune response;GO:0007049//cell cycle;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045765//regulation of angiogenesis;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0071363//cellular response to growth factor stimulus;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0060761//negative regulation of response to cytokine stimulus;GO:0050728//negative regulation of inflammatory response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0002224//toll-like receptor signaling pathway;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0019933//cAMP-mediated signaling,GO:0004707//MAP kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0051019//mitogen-activated protein kinase binding,K04464//GnRH signaling pathway;Gap junction;MAPK signaling pathway;MAPK signaling pathway - yeast;Neurotrophin signaling pathway
5599,76,0,39,0,77,68,4,68,28,0,0,0,MAPK8;mitogen-activated protein kinase 8,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0034134//toll-like receptor 2 signaling pathway;GO:0001503//ossification;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0090045//positive regulation of deacetylase activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0046686//response to cadmium ion;GO:0018105//peptidyl-serine phosphorylation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0071732//cellular response to nitric oxide;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0007258//JUN phosphorylation;GO:0006915//apoptotic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032880//regulation of protein localization;GO:0045087//innate immune response;GO:0034146//toll-like receptor 5 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0032091//negative regulation of protein binding;GO:0010628//positive regulation of gene expression;GO:0031063//regulation of histone deacetylation;GO:0009411//response to UV;GO:0071222//cellular response to lipopolysaccharide;GO:2000017//positive regulation of determination of dorsal identity;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0006950//response to stress;GO:0034162//toll-like receptor 9 signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0097300//programmed necrotic cell death;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0035033//histone deacetylase regulator activity;GO:0005515//protein binding;GO:0004705//JUN kinase activity;GO:0042826//histone deacetylase binding;GO:0005524//ATP binding,K04440//Retrograde endocannabinoid signaling;NOD-like receptor signaling pathway;Shigellosis;HTLV-I infection;Focal adhesion;Toxoplasmosis;Osteoclast differentiation;Pertussis;Influenza A;Toll-like receptor signaling pathway;GnRH signaling pathway;Pathways in cancer;Dopaminergic synapse;Pancreatic cancer;ErbB signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;MAPK signaling pathway;Herpes simplex infection;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Adipocytokine signaling pathway;Hepatitis C;Neurotrophin signaling pathway;Tuberculosis;Progesterone-mediated oocyte maturation;Insulin signaling pathway;Salmonella infection;Colorectal cancer;Type II diabetes mellitus;T cell receptor signaling pathway;Protein processing in endoplasmic reticulum;Wnt signaling pathway
55998,0,0,0,0,0,0,0,0,13,0,0,0,NXF5;nuclear RNA export factor 5,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050658//RNA transport;GO:0006406//mRNA export from nucleus;GO:0007275//multicellular organismal development,GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003723//RNA binding,K14284//Herpes simplex infection;Ribosome biogenesis in eukaryotes;Influenza A;RNA transport;mRNA surveillance pathway
55999,0,0,0,0,0,12,45,0,0,0,4,0,NXF4;nuclear RNA export factor 4 pseudogene,-,-,-,K14284//Herpes simplex infection;RNA transport;mRNA surveillance pathway;Influenza A;Ribosome biogenesis in eukaryotes
56,0,0,0,0,0,0,0,0,56,0,13,0,ACRV1;acrosomal vesicle protein 1,GO:0001669//acrosomal vesicle,GO:0007275//multicellular organismal development,-,-
5600,0,0,0,0,5,0,63,0,13,0,12,0,MAPK11;mitogen-activated protein kinase 11,GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000187//activation of MAPK activity;GO:0006351//transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0010467//gene expression;GO:0045087//innate immune response;GO:0051149//positive regulation of muscle cell differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0007265//Ras protein signal transduction;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006950//response to stress;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006468//protein phosphorylation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0042692//muscle cell differentiation;GO:0007165//signal transduction",GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity,K04441//Progesterone-mediated oocyte maturation;Influenza A;Toll-like receptor signaling pathway;Tuberculosis;Pertussis;Salmonella infection;GnRH signaling pathway;Dopaminergic synapse;MAPK signaling pathway - yeast;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;T cell receptor signaling pathway;MAPK signaling pathway;NOD-like receptor signaling pathway;Leukocyte transendothelial migration;Shigellosis;Retrograde endocannabinoid signaling;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);VEGF signaling pathway;Hepatitis C;Neurotrophin signaling pathway;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation
56000,63,0,0,0,0,0,0,43,40,157,0,0,NXF3;nuclear RNA export factor 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0042272//nuclear RNA export factor complex,GO:0006406//mRNA export from nucleus;GO:0016973//poly(A)+ mRNA export from nucleus,GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding,K14284//Herpes simplex infection;RNA transport;mRNA surveillance pathway;Ribosome biogenesis in eukaryotes;Influenza A
56005,0,0,0,0,1,0,0,0,8,0,0,0,C19orf10;chromosome 19 open reading frame 10,GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006987//activation of signaling protein activity involved in unfolded protein response,-,-
56006,86,0,1,0,10,14,37,0,57,25,1,0,SMG9;SMG9 nonsense mediated mRNA decay factor,GO:0005829//cytosol;GO:0005622//intracellular,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010467//gene expression;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0005515//protein binding;GO:0042802//identical protein binding,-
5601,0,46,0,16,105,0,2,0,17,0,0,0,MAPK9;mitogen-activated protein kinase 9,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005654//nucleoplasm,"GO:0034644//cellular response to UV;GO:0046686//response to cadmium ion;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042493//response to drug;GO:0014075//response to amine;GO:0031396//regulation of protein ubiquitination;GO:0010770//positive regulation of cell morphogenesis involved in differentiation;GO:0031175//neuron projection development;GO:0034134//toll-like receptor 2 signaling pathway;GO:0009612//response to mechanical stimulus;GO:0006626//protein targeting to mitochondrion;GO:0007258//JUN phosphorylation;GO:0071363//cellular response to growth factor stimulus;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0001836//release of cytochrome c from mitochondria;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0034146//toll-like receptor 5 signaling pathway;GO:0010628//positive regulation of gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007417//central nervous system development;GO:0046328//regulation of JNK cascade;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009636//response to toxic substance;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0071347//cellular response to interleukin-1;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032308//positive regulation of prostaglandin secretion;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006950//response to stress;GO:0001934//positive regulation of protein phosphorylation;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0071356//cellular response to tumor necrosis factor;GO:0071222//cellular response to lipopolysaccharide",GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004705//JUN kinase activity;GO:0008134//transcription factor binding,K04440//HTLV-I infection;NOD-like receptor signaling pathway;Shigellosis;Retrograde endocannabinoid signaling;Toxoplasmosis;Osteoclast differentiation;Focal adhesion;Pancreatic cancer;Pathways in cancer;GnRH signaling pathway;Dopaminergic synapse;Influenza A;Toll-like receptor signaling pathway;Pertussis;MAPK signaling pathway;Herpes simplex infection;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;ErbB signaling pathway;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Hepatitis C;Neurotrophin signaling pathway;Adipocytokine signaling pathway;Insulin signaling pathway;Salmonella infection;Progesterone-mediated oocyte maturation;Tuberculosis;Wnt signaling pathway;T cell receptor signaling pathway;Protein processing in endoplasmic reticulum;Colorectal cancer;Type II diabetes mellitus
5602,0,0,1,9,64,13,0,0,24,0,0,0,MAPK10;mitogen-activated protein kinase 10,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0045087//innate immune response;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0000187//activation of MAPK activity;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007258//JUN phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway,GO:0005524//ATP binding;GO:0004708//MAP kinase kinase activity;GO:0004705//JUN kinase activity;GO:0005515//protein binding,K04440//Osteoclast differentiation;Toxoplasmosis;Focal adhesion;HTLV-I infection;NOD-like receptor signaling pathway;Shigellosis;Retrograde endocannabinoid signaling;Herpes simplex infection;MAPK signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;ErbB signaling pathway;Pancreatic cancer;GnRH signaling pathway;Pathways in cancer;Dopaminergic synapse;Influenza A;Toll-like receptor signaling pathway;Pertussis;Neurotrophin signaling pathway;Hepatitis C;Adipocytokine signaling pathway;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Wnt signaling pathway;T cell receptor signaling pathway;Protein processing in endoplasmic reticulum;Colorectal cancer;Type II diabetes mellitus;Insulin signaling pathway;Salmonella infection;Progesterone-mediated oocyte maturation;Tuberculosis
5603,0,1,1,4,31,14,1,72,14,118,0,0,MAPK13;mitogen-activated protein kinase 13,GO:0005829//cytosol,"GO:0006351//transcription, DNA-templated;GO:0000165//MAPK cascade;GO:0050729//positive regulation of inflammatory response;GO:0006950//response to stress;GO:0035556//intracellular signal transduction;GO:0006970//response to osmotic stress;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0007049//cell cycle;GO:0018105//peptidyl-serine phosphorylation;GO:0007265//Ras protein signal transduction;GO:0006355//regulation of transcription, DNA-templated",GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004707//MAP kinase activity;GO:0004674//protein serine/threonine kinase activity,K04441//GnRH signaling pathway;MAPK signaling pathway - yeast;Dopaminergic synapse;Salmonella infection;Tuberculosis;Pertussis;Progesterone-mediated oocyte maturation;Influenza A;Toll-like receptor signaling pathway;T cell receptor signaling pathway;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Retrograde endocannabinoid signaling;NOD-like receptor signaling pathway;Shigellosis;Leukocyte transendothelial migration;Toxoplasmosis;Osteoclast differentiation;Leishmaniasis;Neurotrophin signaling pathway;Hepatitis C;VEGF signaling pathway
56033,0,0,0,0,0,0,0,0,26,0,6,0,BARX1;BARX homeobox 1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0048536//spleen development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0009952//anterior/posterior pattern specification;GO:0007267//cell-cell signaling;GO:0030855//epithelial cell differentiation;GO:0055123//digestive system development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
56034,0,0,0,0,0,0,0,0,11,135,0,0,PDGFC;platelet derived growth factor C,GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space,GO:0048146//positive regulation of fibroblast proliferation;GO:0009887//organ morphogenesis;GO:0007417//central nervous system development;GO:0045740//positive regulation of DNA replication;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0051781//positive regulation of cell division;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0071230//cellular response to amino acid stimulus,GO:0005161//platelet-derived growth factor receptor binding;GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K05450//Focal adhesion;Prostate cancer;Cytokine-cytokine receptor interaction;Melanoma;Regulation of actin cytoskeleton;Gap junction
5604,0,26,42,65,137,7,0,0,6,0,48,0,MAP2K1;mitogen-activated protein kinase kinase 1,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0032839//dendrite cytoplasm;GO:0005794//Golgi apparatus;GO:0005770//late endosome;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0043204//perikaryon;GO:0005925//focal adhesion;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005815//microtubule organizing center,GO:0051291//protein heterooligomerization;GO:0006928//cellular component movement;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0032320//positive regulation of Ras GTPase activity;GO:0030216//keratinocyte differentiation;GO:0045597//positive regulation of cell differentiation;GO:0060711//labyrinthine layer development;GO:0060674//placenta blood vessel development;GO:0007165//signal transduction;GO:0007067//mitotic nuclear division;GO:2000641//regulation of early endosome to late endosome transport;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007411//axon guidance;GO:0030335//positive regulation of cell migration;GO:0051403//stress-activated MAPK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0051384//response to glucocorticoid;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0090398//cellular senescence;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0047496//vesicle transport along microtubule;GO:0048870//cell motility;GO:0006979//response to oxidative stress;GO:0034162//toll-like receptor 9 signaling pathway;GO:0048678//response to axon injury;GO:0008286//insulin receptor signaling pathway;GO:0032872//regulation of stress-activated MAPK cascade;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006935//chemotaxis;GO:0007050//cell cycle arrest;GO:0032402//melanosome transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0003056//regulation of vascular smooth muscle contraction;GO:0090170//regulation of Golgi inheritance;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007265//Ras protein signal transduction;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0045087//innate immune response,GO:0004672//protein kinase activity;GO:0004708//MAP kinase kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004728//receptor signaling protein tyrosine phosphatase activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0017016//Ras GTPase binding;GO:0004713//protein tyrosine kinase activity,K04368//Vascular smooth muscle contraction;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Colorectal cancer;Insulin signaling pathway;Progesterone-mediated oocyte maturation;Long-term potentiation;Prostate cancer;Regulation of actin cytoskeleton;Melanoma;Neurotrophin signaling pathway;Non-small cell lung cancer;Dorso-ventral axis formation;Melanogenesis;Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Oocyte meiosis;MAPK signaling pathway;Renal cell carcinoma;Plant-pathogen interaction;Bladder cancer;ErbB signaling pathway;Pancreatic cancer;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Influenza A;Toll-like receptor signaling pathway;Alcoholism;Serotonergic synapse;Prion diseases;MAPK signaling pathway - fly;Osteoclast differentiation;Endometrial cancer;Thyroid cancer;Focal adhesion;VEGF signaling pathway;Glioma;Long-term depression;Fc gamma R-mediated phagocytosis
5605,0,0,2,13,3,0,0,0,2,0,0,0,MAP2K2;mitogen-activated protein kinase kinase 2,GO:0005576//extracellular region;GO:0005911//cell-cell junction;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0009898//cytoplasmic side of plasma membrane;GO:0005770//late endosome;GO:0005794//Golgi apparatus;GO:0005769//early endosome;GO:0005778//peroxisomal membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005874//microtubule;GO:0048471//perinuclear region of cytoplasm,GO:0034134//toll-like receptor 2 signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007411//axon guidance;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0051403//stress-activated MAPK cascade;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000165//MAPK cascade;GO:0000187//activation of MAPK activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:2000641//regulation of early endosome to late endosome transport;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0070371//ERK1 and ERK2 cascade;GO:0007265//Ras protein signal transduction;GO:2000147//positive regulation of cell motility;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0007264//small GTPase mediated signal transduction;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000186//activation of MAPKK activity;GO:0090170//regulation of Golgi inheritance;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0032872//regulation of stress-activated MAPK cascade;GO:0036289//peptidyl-serine autophosphorylation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0032947//protein complex scaffold;GO:0097110//scaffold protein binding;GO:0004713//protein tyrosine kinase activity;GO:0043539//protein serine/threonine kinase activator activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0005524//ATP binding,K04369//B cell receptor signaling pathway;Long-term depression;Fc epsilon RI signaling pathway;Acute myeloid leukemia;Glioma;VEGF signaling pathway;Melanogenesis;Thyroid cancer;Non-small cell lung cancer;Endometrial cancer;Prion diseases;Melanoma;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Prostate cancer;Long-term potentiation;Toll-like receptor signaling pathway;Influenza A;Gap junction;Pathways in cancer;GnRH signaling pathway;Insulin signaling pathway;ErbB signaling pathway;Bladder cancer;Renal cell carcinoma;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Chronic myeloid leukemia;Vascular smooth muscle contraction
56052,0,77,45,85,220,0,40,1,36,1,238,0,"ALG1;ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0009103//lipopolysaccharide biosynthetic process;GO:0006486//protein glycosylation;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0097502//mannosylation,GO:0004578//chitobiosyldiphosphodolichol beta-mannosyltransferase activity;GO:0000030//mannosyltransferase activity,K03842//Metabolic pathways;Various types of N-glycan biosynthesis;N-Glycan biosynthesis
5606,29,0,0,0,3,0,5,67,1,0,13,0,MAP2K3;mitogen-activated protein kinase kinase 3,GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0016020//membrane,"GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0042035//regulation of cytokine biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060048//cardiac muscle contraction;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0045860//positive regulation of protein kinase activity;GO:0007165//signal transduction;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway",GO:0004674//protein serine/threonine kinase activity;GO:0019901//protein kinase binding;GO:0004708//MAP kinase kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity,K04432//Toll-like receptor signaling pathway;Influenza A;GnRH signaling pathway;Fc epsilon RI signaling pathway;Epstein-Barr virus infection;MAPK signaling pathway;Toxoplasmosis;Amyotrophic lateral sclerosis (ALS)
56061,0,1,2,19,109,15,17,0,37,0,0,0,UBFD1;ubiquitin family domain containing 1,-,-,GO:0044822//poly(A) RNA binding,-
56062,0,0,0,0,0,56,0,0,52,0,0,0,KLHL4;kelch-like family member 4,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,GO:0003779//actin binding,-
56063,0,0,0,0,1,3,0,0,0,0,17,0,TMEM234;transmembrane protein 234,GO:0016021//integral component of membrane,-,-,-
5607,66,35,0,0,15,29,78,0,20,0,0,0,MAP2K5;mitogen-activated protein kinase kinase 5,GO:0005634//nucleus;GO:0005819//spindle;GO:0005829//cytosol,GO:0000187//activation of MAPK activity;GO:0030307//positive regulation of cell growth;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070375//ERK5 cascade;GO:0045415//negative regulation of interleukin-8 biosynthetic process;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0007507//heart development;GO:0051247//positive regulation of protein metabolic process;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0071363//cellular response to growth factor stimulus;GO:0060761//negative regulation of response to cytokine stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071499//cellular response to laminar fluid shear stress;GO:0007165//signal transduction;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034115//negative regulation of heterotypic cell-cell adhesion,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity,K04463//Neurotrophin signaling pathway;Gap junction;MAPK signaling pathway
5608,55,0,0,0,0,0,0,0,15,0,0,0,MAP2K6;mitogen-activated protein kinase kinase 6,GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0005654//nucleoplasm,"GO:0072709//cellular response to sorbitol;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0007050//cell cycle arrest;GO:0007165//signal transduction;GO:0042692//muscle cell differentiation;GO:0006975//DNA damage induced protein phosphorylation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0051149//positive regulation of muscle cell differentiation;GO:0042493//response to drug;GO:0060048//cardiac muscle contraction;GO:0034134//toll-like receptor 2 signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0002931//response to ischemia;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0000187//activation of MAPK activity;GO:0051403//stress-activated MAPK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway",GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004708//MAP kinase kinase activity;GO:0019901//protein kinase binding;GO:0004674//protein serine/threonine kinase activity,K04433//Epstein-Barr virus infection;Osteoclast differentiation;Toxoplasmosis;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Influenza A;Toll-like receptor signaling pathway;GnRH signaling pathway;Fc epsilon RI signaling pathway
5609,102,0,0,2,0,0,0,0,10,0,1,0,MAP2K7;mitogen-activated protein kinase kinase 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0009411//response to UV;GO:0009408//response to heat;GO:0002224//toll-like receptor signaling pathway;GO:0043525//positive regulation of neuron apoptotic process;GO:0034166//toll-like receptor 10 signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0045087//innate immune response;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade;GO:0034134//toll-like receptor 2 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0007257//activation of JUN kinase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006970//response to osmotic stress;GO:0072709//cellular response to sorbitol;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0000287//magnesium ion binding;GO:0008022//protein C-terminus binding;GO:0004708//MAP kinase kinase activity;GO:0019901//protein kinase binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0008545//JUN kinase kinase activity;GO:0019903//protein phosphatase binding;GO:0005524//ATP binding,K04431//Influenza A;Toll-like receptor signaling pathway;GnRH signaling pathway;Fc epsilon RI signaling pathway;ErbB signaling pathway;Epstein-Barr virus infection;Osteoclast differentiation;Protein processing in endoplasmic reticulum;T cell receptor signaling pathway;MAPK signaling pathway;Neurotrophin signaling pathway
56097,0,0,0,0,6,0,27,0,0,0,0,360,"PCDHGC5;protocadherin gamma subfamily C, 5",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56098,0,0,0,0,0,4,11,0,73,125,9,0,"PCDHGC4;protocadherin gamma subfamily C, 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56099,0,0,0,0,0,0,0,0,15,116,0,0,"PCDHGB7;protocadherin gamma subfamily B, 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
5610,0,28,2,62,194,15,43,0,37,0,0,0,EIF2AK2;eukaryotic translation initiation factor 2-alpha kinase 2,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane,"GO:0006468//protein phosphorylation;GO:0033689//negative regulation of osteoblast proliferation;GO:0045071//negative regulation of viral genome replication;GO:0017148//negative regulation of translation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0046777//protein autophosphorylation;GO:0051607//defense response to virus;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0009615//response to virus;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:1901224//positive regulation of NIK/NF-kappaB signaling;GO:0008285//negative regulation of cell proliferation;GO:1900225//regulation of NLRP3 inflammasome complex assembly;GO:0019054//modulation by virus of host process;GO:0001819//positive regulation of cytokine production;GO:0000186//activation of MAPKK activity;GO:0006412//translation;GO:0030683//evasion or tolerance by virus of host immune response;GO:0006351//transcription, DNA-templated;GO:0019048//modulation by virus of host morphology or physiology;GO:0019058//viral life cycle;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0035455//response to interferon-alpha;GO:1902036//regulation of hematopoietic stem cell differentiation;GO:1902033//regulation of hematopoietic stem cell proliferation;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production",GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0008601//protein phosphatase type 2A regulator activity;GO:0003725//double-stranded RNA binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,K08860//Epstein-Barr virus infection;Influenza A;Measles;Alzheimer's disease;Hepatitis C;Herpes simplex infection;Protein processing in endoplasmic reticulum
56100,0,0,0,0,0,0,0,0,32,0,0,0,"PCDHGB6;protocadherin gamma subfamily B, 6",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56101,0,0,0,0,0,0,0,0,17,0,7,0,"PCDHGB5;protocadherin gamma subfamily B, 5",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56102,0,0,0,0,0,0,0,0,5,0,0,0,"PCDHGB3;protocadherin gamma subfamily B, 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56103,0,0,0,0,0,0,10,0,25,3,0,0,"PCDHGB2;protocadherin gamma subfamily B, 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56104,0,0,0,0,0,0,0,0,0,0,9,0,"PCDHGB1;protocadherin gamma subfamily B, 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56106,0,0,0,0,0,32,0,0,8,0,0,0,"PCDHGA10;protocadherin gamma subfamily A, 10",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56107,0,0,0,0,0,0,0,0,14,0,0,0,"PCDHGA9;protocadherin gamma subfamily A, 9",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007283//spermatogenesis,GO:0005509//calcium ion binding;GO:0044822//poly(A) RNA binding,-
56108,0,0,0,0,0,0,8,0,0,0,10,0,"PCDHGA7;protocadherin gamma subfamily A, 7",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
5611,0,0,41,1,44,14,36,43,20,0,0,0,"DNAJC3;DnaJ (Hsp40) homolog, subfamily C, member 3",GO:0031205//endoplasmic reticulum Sec complex;GO:0005788//endoplasmic reticulum lumen;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0051607//defense response to virus;GO:0006469//negative regulation of protein kinase activity;GO:0044267//cellular protein metabolic process;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0051087//chaperone binding;GO:0004860//protein kinase inhibitor activity;GO:0051787//misfolded protein binding,K09523//Influenza A;Protein processing in endoplasmic reticulum
56110,0,0,0,0,0,10,0,0,1,0,5,0,"PCDHGA5;protocadherin gamma subfamily A, 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56111,0,0,0,0,0,0,31,43,22,0,0,0,"PCDHGA4;protocadherin gamma subfamily A, 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007283//spermatogenesis,GO:0005509//calcium ion binding,-
56112,0,0,0,0,0,0,0,0,0,0,0,66,"PCDHGA3;protocadherin gamma subfamily A, 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56113,11,0,0,0,0,0,23,46,0,149,0,0,"PCDHGA2;protocadherin gamma subfamily A, 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
5612,0,46,0,1,116,0,0,0,52,0,0,0,"PRKRIR;protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",GO:0005634//nucleus,GO:0006950//response to stress;GO:0007165//signal transduction;GO:0008285//negative regulation of cell proliferation,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity,-
56121,0,0,0,0,0,0,0,0,3,0,0,0,PCDHB15;protocadherin beta 15,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56122,0,0,0,0,0,0,6,0,37,0,0,0,PCDHB14;protocadherin beta 14,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007416//synapse assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission,GO:0005509//calcium ion binding,-
56123,0,0,0,0,0,0,0,0,16,0,0,19,PCDHB13;protocadherin beta 13,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007416//synapse assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission,GO:0005509//calcium ion binding,-
56124,0,31,0,0,0,0,21,0,31,0,0,0,PCDHB12;protocadherin beta 12,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56125,0,0,0,0,0,33,0,0,1,0,3,0,PCDHB11;protocadherin beta 11,GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane,GO:0007416//synapse assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,-
56126,0,0,0,0,0,0,0,0,3,0,0,0,PCDHB10;protocadherin beta 10,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007268//synaptic transmission;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007416//synapse assembly,GO:0005509//calcium ion binding,-
56127,0,0,0,0,0,0,31,0,29,10,6,0,PCDHB9;protocadherin beta 9,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission;GO:0007416//synapse assembly,GO:0005509//calcium ion binding,-
56128,52,0,0,0,0,0,0,0,0,0,0,0,PCDHB8;protocadherin beta 8,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56129,48,0,0,0,0,17,0,0,0,0,0,0,PCDHB7;protocadherin beta 7,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
5613,96,0,0,0,1,0,34,0,18,0,0,0,"PRKX;protein kinase, X-linked",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030155//regulation of cell adhesion;GO:2000696//regulation of epithelial cell differentiation involved in kidney development;GO:0007155//cell adhesion;GO:0060993//kidney morphogenesis;GO:0001935//endothelial cell proliferation;GO:0031589//cell-substrate adhesion;GO:0060562//epithelial tube morphogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0030334//regulation of cell migration;GO:0030099//myeloid cell differentiation;GO:0046777//protein autophosphorylation;GO:0001525//angiogenesis;GO:0043542//endothelial cell migration,GO:0004691//cAMP-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding,K04345//Serotonergic synapse;Alcoholism;Dopaminergic synapse;Cocaine addiction;Gap junction;GnRH signaling pathway;Chemokine signaling pathway;Meiosis - yeast;Epstein-Barr virus infection;MAPK signaling pathway;Hedgehog signaling pathway;Apoptosis;Morphine addiction;Oocyte meiosis;Endocrine and other factor-regulated calcium reabsorption;Olfactory transduction;Calcium signaling pathway;Retrograde endocannabinoid signaling;HTLV-I infection;Gastric acid secretion;Bile secretion;Prion diseases;Long-term potentiation;Progesterone-mediated oocyte maturation;Insulin signaling pathway;Amoebiasis;Glutamatergic synapse;Amphetamine addiction;Taste transduction;Vasopressin-regulated water reabsorption;Vascular smooth muscle contraction;Wnt signaling pathway;Dilated cardiomyopathy;Salivary secretion;GABAergic synapse;Cholinergic synapse;Vibrio cholerae infection;Melanogenesis
56131,0,0,0,0,0,0,69,17,25,0,13,0,PCDHB4;protocadherin beta 4,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0045111//intermediate filament cytoskeleton,GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155//cell adhesion;GO:0007416//synapse assembly,GO:0005509//calcium ion binding,-
56132,0,0,39,0,6,0,37,0,23,0,4,0,PCDHB3;protocadherin beta 3,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane,GO:0007416//synapse assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,-
56133,0,34,0,0,0,0,0,43,0,0,0,317,PCDHB2;protocadherin beta 2,GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane,GO:0007416//synapse assembly;GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007268//synaptic transmission;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0005509//calcium ion binding,-
56134,0,0,0,0,0,8,46,0,2,0,13,34,"PCDHAC2;protocadherin alpha subfamily C, 2",GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56135,0,0,0,0,0,0,0,39,38,0,0,0,"PCDHAC1;protocadherin alpha subfamily C, 1",GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56137,0,0,1,0,0,13,0,0,1,3,13,0,PCDHA12;protocadherin alpha 12,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56138,0,76,0,20,0,0,0,113,35,0,45,0,PCDHA11;protocadherin alpha 11,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56139,0,0,0,8,0,0,0,0,17,0,0,0,PCDHA10;protocadherin alpha 10,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56140,19,0,0,0,0,12,0,47,0,1,0,0,PCDHA8;protocadherin alpha 8,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56141,0,0,0,0,0,0,0,0,0,0,7,0,PCDHA7;protocadherin alpha 7,GO:0005887//integral component of plasma membrane,GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,-
56142,100,0,0,0,0,14,0,0,23,0,0,0,PCDHA6;protocadherin alpha 6,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56143,2,0,0,0,0,0,0,96,0,0,0,0,PCDHA5;protocadherin alpha 5,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56144,0,0,0,0,0,27,0,0,0,0,0,0,PCDHA4;protocadherin alpha 4,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
56145,0,0,96,0,0,0,0,217,0,0,26,0,PCDHA3;protocadherin alpha 3,GO:0005887//integral component of plasma membrane,GO:0007399//nervous system development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007155//cell adhesion,GO:0005509//calcium ion binding,-
56146,0,0,0,0,0,0,23,0,14,0,8,0,PCDHA2;protocadherin alpha 2,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56147,0,0,0,0,0,22,1,0,32,0,0,0,PCDHA1;protocadherin alpha 1,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0007155//cell adhesion;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007399//nervous system development,GO:0005509//calcium ion binding,-
56154,0,0,46,0,0,63,88,0,122,54,0,0,TEX15;testis expressed 15,-,GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0030539//male genitalia development;GO:0007140//male meiosis;GO:0032880//regulation of protein localization;GO:0034502//protein localization to chromosome;GO:0048873//homeostasis of number of cells within a tissue;GO:0009566//fertilization;GO:0007283//spermatogenesis;GO:0007130//synaptonemal complex assembly,-,K14007//Protein processing in endoplasmic reticulum
56155,0,22,0,0,25,0,40,0,79,0,37,0,TEX14;testis expressed 14,GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0045171//intercellular bridge;GO:0030496//midbody;GO:0005623//cell;GO:0005737//cytoplasm,GO:0007094//mitotic spindle assembly checkpoint;GO:0032466//negative regulation of cytokinesis;GO:0032091//negative regulation of protein binding;GO:0006468//protein phosphorylation;GO:0051306//mitotic sister chromatid separation;GO:0043063//intercellular bridge organization;GO:0007140//male meiosis;GO:0008608//attachment of spindle microtubules to kinetochore,GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0005515//protein binding,K05704//Shigellosis;Tuberculosis;Endocytosis;Bacterial invasion of epithelial cells;GnRH signaling pathway;Chemokine signaling pathway;GABAergic synapse;Gap junction;Tight junction;Epithelial cell signaling in Helicobacter pylori infection;VEGF signaling pathway;Focal adhesion;Adherens junction;ErbB signaling pathway;Regulation of actin cytoskeleton;K05705//Tight junction;Adherens junction;K04422//MAPK signaling pathway
56157,0,0,0,0,0,0,0,0,9,0,0,0,TEX13A;testis expressed 13A,-,-,GO:0008270//zinc ion binding,-
56158,0,0,0,0,0,12,0,0,14,0,0,0,TEX12;testis expressed 12,GO:0000801//central element,GO:0007130//synaptonemal complex assembly;GO:0000711//meiotic DNA repair synthesis,-,-
56159,0,0,0,0,0,53,29,0,55,0,1,0,TEX11;testis expressed 11,GO:0000801//central element;GO:0000795//synaptonemal complex,GO:0006311//meiotic gene conversion;GO:0051026//chiasma assembly;GO:0009566//fertilization;GO:0008584//male gonad development;GO:0007131//reciprocal meiotic recombination;GO:0007060//male meiosis chromosome segregation;GO:0043066//negative regulation of apoptotic process;GO:0007130//synaptonemal complex assembly;GO:0000712//resolution of meiotic recombination intermediates,GO:0005515//protein binding,K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Biotin metabolism;Arginine and proline metabolism;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
5616,0,1,0,1,12,0,0,0,0,0,0,0,"PRKY;protein kinase, Y-linked, pseudogene",-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04345//Epstein-Barr virus infection;Morphine addiction;Oocyte meiosis;Apoptosis;Hedgehog signaling pathway;MAPK signaling pathway;Alcoholism;Serotonergic synapse;Meiosis - yeast;GnRH signaling pathway;Chemokine signaling pathway;Dopaminergic synapse;Cocaine addiction;Gap junction;Bile secretion;Gastric acid secretion;Prion diseases;Olfactory transduction;Retrograde endocannabinoid signaling;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;HTLV-I infection;Amoebiasis;Wnt signaling pathway;Vascular smooth muscle contraction;Vasopressin-regulated water reabsorption;Taste transduction;Glutamatergic synapse;Amphetamine addiction;Progesterone-mediated oocyte maturation;Long-term potentiation;Insulin signaling pathway;Vibrio cholerae infection;Melanogenesis;Salivary secretion;Dilated cardiomyopathy;Cholinergic synapse;GABAergic synapse
56160,0,0,0,0,26,16,0,0,17,0,0,0,NDNL2;necdin-like 2,"GO:0030915//Smc5-Smc6 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000781//chromosome, telomeric region",GO:0006310//DNA recombination;GO:0006281//DNA repair;GO:0031398//positive regulation of protein ubiquitination;GO:0040008//regulation of growth,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
56163,298,0,0,0,0,39,25,113,94,0,1,0,RNF17;ring finger protein 17,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0008152//metabolic process;GO:0007286//spermatid development,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0003676//nucleic acid binding;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding",K15979//Epstein-Barr virus infection
56164,0,0,0,0,0,0,14,0,88,18,0,0,STK31;serine/threonine kinase 31,GO:0001669//acrosomal vesicle,GO:0006468//protein phosphorylation,"GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding;GO:0016788//hydrolase activity, acting on ester bonds",-
56165,23,0,0,0,0,42,0,0,27,41,0,0,TDRD1;tudor domain containing 1,GO:0043186//P granule;GO:0071546//pi-body;GO:0005737//cytoplasm;GO:0033391//chromatoid body,GO:0031047//gene silencing by RNA;GO:0007126//meiotic nuclear division;GO:0007281//germ cell development;GO:0007275//multicellular organismal development;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation;GO:0007283//spermatogenesis,GO:0046872//metal ion binding,K15979//Epstein-Barr virus infection
56169,12,0,0,0,0,0,0,0,32,0,0,0,GSDMC;gasdermin C,GO:0005739//mitochondrion;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm,-,-,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
5617,0,0,0,0,0,0,0,0,13,0,0,0,PRL;prolactin,GO:0030141//secretory granule;GO:0005576//extracellular region,GO:0032355//response to estradiol;GO:0007262//STAT protein import into nucleus;GO:0007567//parturition;GO:0040014//regulation of multicellular organism growth;GO:0007595//lactation;GO:0042698//ovulation cycle;GO:0007623//circadian rhythm;GO:0033555//multicellular organismal response to stress;GO:0030278//regulation of ossification;GO:0007166//cell surface receptor signaling pathway;GO:0007584//response to nutrient;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0046427//positive regulation of JAK-STAT cascade;GO:0045471//response to ethanol;GO:0050679//positive regulation of epithelial cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0008283//cell proliferation,GO:0005179//hormone activity;GO:0005515//protein binding;GO:0005148//prolactin receptor binding,K05439//Neuroactive ligand-receptor interaction;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
56171,0,19,1,12,9,39,0,75,216,1,0,0,"DNAH7;dynein, axonemal, heavy chain 7",GO:0005874//microtubule;GO:0005929//cilium;GO:0005858//axonemal dynein complex,GO:0001539//cilium or flagellum-dependent cell motility;GO:0008152//metabolic process;GO:0003341//cilium movement;GO:0006200//ATP catabolic process,GO:0003777//microtubule motor activity;GO:0005509//calcium ion binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,K10408//Huntington's disease
56172,173,87,1,102,208,0,15,11,224,215,97,0,ANKH;ANKH inorganic pyrophosphate transport regulator,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0019867//outer membrane;GO:0005886//plasma membrane,GO:0001501//skeletal system development;GO:0007626//locomotory behavior;GO:0030500//regulation of bone mineralization;GO:0030505//inorganic diphosphate transport;GO:0035435//phosphate ion transmembrane transport,GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0015114//phosphate ion transmembrane transporter activity;GO:0030504//inorganic diphosphate transmembrane transporter activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
5618,0,40,0,0,10,12,20,0,140,0,31,0,PRLR;prolactin receptor,GO:0031904//endosome lumen;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0043066//negative regulation of apoptotic process;GO:0042110//T cell activation;GO:0007566//embryo implantation;GO:0007166//cell surface receptor signaling pathway;GO:0038161//prolactin signaling pathway;GO:0006694//steroid biosynthetic process;GO:0007171//activation of transmembrane receptor protein tyrosine kinase activity;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0007595//lactation;GO:0042977//activation of JAK2 kinase activity,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004925//prolactin receptor activity;GO:0017046//peptide hormone binding;GO:0042978//ornithine decarboxylase activator activity,K05081//Neuroactive ligand-receptor interaction;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
56180,0,0,0,0,40,10,0,0,44,0,0,0,MOSPD1;motile sperm domain containing 1,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0005198//structural molecule activity,-
56181,0,60,48,6,31,0,0,0,16,0,0,0,MTFR1L;mitochondrial fission regulator 1-like,-,-,-,-
5619,100,0,0,0,2,16,0,0,0,0,0,0,PRM1;protamine 1,GO:0005654//nucleoplasm;GO:0000786//nucleosome,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0006323//DNA packaging;GO:0030261//chromosome condensation;GO:0007283//spermatogenesis,GO:0003677//DNA binding,-
5620,0,32,4,14,18,0,0,1,0,0,0,1,PRM2;protamine 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000786//nucleosome,GO:0030154//cell differentiation;GO:0030261//chromosome condensation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0006323//DNA packaging,GO:0003677//DNA binding,-
56203,0,0,0,0,0,25,0,0,47,0,0,0,LMOD3;leiomodin 3 (fetal),GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,GO:0005523//tropomyosin binding,-
56204,251,0,1,9,47,7,20,0,9,0,0,0,"FAM214A;family with sequence similarity 214, member A",-,-,-,-
5621,0,0,0,5,0,0,0,0,53,0,2,0,PRNP;prion protein,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0031225//anchored component of membrane;GO:0019898//extrinsic component of membrane,GO:0032880//regulation of protein localization;GO:0046007//negative regulation of activated T cell proliferation;GO:0032703//negative regulation of interleukin-2 production;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051260//protein homooligomerization;GO:0070885//negative regulation of calcineurin-NFAT signaling cascade;GO:0007611//learning or memory;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0032689//negative regulation of interferon-gamma production;GO:0046686//response to cadmium ion;GO:0001933//negative regulation of protein phosphorylation;GO:0007411//axon guidance;GO:0043066//negative regulation of apoptotic process;GO:0008152//metabolic process;GO:0006878//cellular copper ion homeostasis;GO:0046688//response to copper ion;GO:0007050//cell cycle arrest;GO:1901379//regulation of potassium ion transmembrane transport;GO:0032700//negative regulation of interleukin-17 production;GO:0006979//response to oxidative stress,GO:0043008//ATP-dependent protein binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042802//identical protein binding;GO:0005507//copper ion binding;GO:0015631//tubulin binding;GO:0051087//chaperone binding,K05634//Prion diseases
5624,0,0,0,0,3,0,0,0,1,48,0,0,PROC;protein C (inactivator of coagulation factors Va and VIIIa),GO:0005788//endoplasmic reticulum lumen;GO:0005886//plasma membrane;GO:0005796//Golgi lumen;GO:0005576//extracellular region,GO:0043687//post-translational protein modification;GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0044267//cellular protein metabolic process;GO:0030195//negative regulation of blood coagulation;GO:0043066//negative regulation of apoptotic process;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004252//serine-type endopeptidase activity,K01344//Complement and coagulation cascades
56241,0,0,0,0,0,1,27,6,8,1,17,0,SUSD2;sushi domain containing 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006955//immune response;GO:0006898//receptor-mediated endocytosis,GO:0030247//polysaccharide binding;GO:0005044//scavenger receptor activity;GO:0005515//protein binding,K04003//Complement and coagulation cascades;Pertussis
56242,0,0,0,0,0,0,0,0,26,0,0,0,ZNF253;zinc finger protein 253,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
56243,65,0,15,26,194,26,45,49,88,116,6,0,KIAA1217;KIAA1217,GO:0005737//cytoplasm,GO:0048706//embryonic skeletal system development,-,-
56245,0,11,0,0,0,0,0,0,25,0,9,0,C21orf62;chromosome 21 open reading frame 62,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
56246,0,1,12,142,135,0,2,0,64,0,196,0,MRAP;melanocortin 2 receptor accessory protein,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030819//positive regulation of cAMP biosynthetic process;GO:0034394//protein localization to cell surface;GO:0050873//brown fat cell differentiation,GO:0031783//type 5 melanocortin receptor binding;GO:0070996//type 1 melanocortin receptor binding;GO:0031780//corticotropin hormone receptor binding;GO:0031782//type 4 melanocortin receptor binding;GO:0005515//protein binding;GO:0031781//type 3 melanocortin receptor binding,-
5625,0,0,0,5,25,0,3,235,22,1,9,0,PRODH;proline dehydrogenase (oxidase) 1,GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0010133//proline catabolic process to glutamate;GO:0055114//oxidation-reduction process;GO:0006562//proline catabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process,GO:0071949//FAD binding;GO:0004657//proline dehydrogenase activity,K00318//Metabolic pathways;Arginine and proline metabolism;Biosynthesis of secondary metabolites
56252,0,47,26,4,105,10,19,36,58,62,3,0,YLPM1;YLP motif containing 1,GO:0005634//nucleus;GO:0016607//nuclear speck,"GO:0032204//regulation of telomere maintenance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K04441//GnRH signaling pathway;Dopaminergic synapse;MAPK signaling pathway - yeast;Salmonella infection;Pertussis;Tuberculosis;Progesterone-mediated oocyte maturation;Influenza A;Toll-like receptor signaling pathway;T cell receptor signaling pathway;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;Chagas disease (American trypanosomiasis);Fc epsilon RI signaling pathway;Retrograde endocannabinoid signaling;NOD-like receptor signaling pathway;Leukocyte transendothelial migration;Shigellosis;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation;Neurotrophin signaling pathway;Hepatitis C;VEGF signaling pathway;K13911//Salivary secretion
56253,0,0,0,0,0,0,0,0,22,0,7,0,CRTAM;cytotoxic and regulatory T cell molecule,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0051606//detection of stimulus;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0050776//regulation of immune response;GO:0002355//detection of tumor cell;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0008037//cell recognition;GO:0001913//T cell mediated cytotoxicity;GO:0050798//activated T cell proliferation;GO:0050715//positive regulation of cytokine secretion,GO:0005102//receptor binding,K06780//Cell adhesion molecules (CAMs)
56254,0,36,3,19,115,0,38,0,47,0,7,0,"RNF20;ring finger protein 20, E3 ubiquitin protein ligase",GO:0005730//nucleolus;GO:0033503//HULC complex;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030336//negative regulation of cell migration;GO:0031062//positive regulation of histone methylation;GO:0000209//protein polyubiquitination;GO:0010390//histone monoubiquitination;GO:0033523//histone H2B ubiquitination",GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0002039//p53 binding;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0042393//histone binding,-
56255,29,0,1,1,0,8,0,0,49,0,13,0,TMX4;thioredoxin-related transmembrane protein 4,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0034976//response to endoplasmic reticulum stress;GO:0006457//protein folding;GO:0045454//cell redox homeostasis,GO:0003756//protein disulfide isomerase activity,K13984//Protein processing in endoplasmic reticulum
56256,0,0,0,0,0,0,1,37,11,0,0,0,SERTAD4;SERTA domain containing 4,GO:0005634//nucleus,-,-,-
56257,0,0,0,0,18,0,0,1,14,0,9,0,MEPCE;methylphosphate capping enzyme,-,GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0040031//snRNA modification;GO:0001510//RNA methylation;GO:0035562//negative regulation of chromatin binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0008173//RNA methyltransferase activity;GO:0044822//poly(A) RNA binding,-
56259,98,26,0,15,18,0,0,0,26,0,0,0,"CTNNBL1;catenin, beta like 1",GO:0016020//membrane;GO:0000974//Prp19 complex;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0016445//somatic diversification of immunoglobulins;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043065//positive regulation of apoptotic process,GO:0019899//enzyme binding;GO:0005515//protein binding,K12864//Spliceosome
5626,0,0,0,0,0,40,26,0,35,0,0,0,PROP1;PROP paired-like homeobox 1,GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0048850//hypophysis morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0009953//dorsal/ventral pattern formation;GO:0060126//somatotropin secreting cell differentiation;GO:0021979//hypothalamus cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016477//cell migration;GO:0001568//blood vessel development,GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0008022//protein C-terminus binding;GO:0008013//beta-catenin binding,-
56260,0,0,0,0,0,0,0,0,0,0,8,0,C8orf44;chromosome 8 open reading frame 44,GO:0005634//nucleus;GO:0005730//nucleolus,-,-,K11447//Transcriptional misregulation in cancer
56261,0,0,0,0,11,6,0,0,62,0,4,0,GPCPD1;glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae),GO:0005829//cytosol,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process,GO:2001070//starch binding;GO:0047389//glycerophosphocholine phosphodiesterase activity,-
56262,149,66,42,42,25,0,0,127,15,1,44,1,"LRRC8A;leucine rich repeat containing 8 family, member A",GO:0034702//ion channel complex;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016020//membrane,GO:0006884//cell volume homeostasis;GO:0002329//pre-B cell differentiation;GO:0006970//response to osmotic stress;GO:0006820//anion transport,GO:0005253//anion channel activity;GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway;K01768//Purine metabolism;Meiosis - yeast
56265,117,0,0,0,0,0,8,0,25,142,1,0,"CPXM1;carboxypeptidase X (M14 family), member 1",GO:0005615//extracellular space,GO:0007155//cell adhesion;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,-
56267,0,0,1,19,45,0,0,0,0,0,0,0,CCBL2;cysteine conjugate-beta lyase 2,GO:0005739//mitochondrion,GO:0009058//biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006520//cellular amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006569//tryptophan catabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0097052//L-kynurenine metabolic process,GO:0030170//pyridoxal phosphate binding;GO:0047804//cysteine-S-conjugate beta-lyase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0047315//kynurenine-glyoxylate transaminase activity;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity,K00816//Metabolic pathways;Tryptophan metabolism;Selenocompound metabolism
56269,0,0,0,0,3,0,0,1,0,0,0,0,"IRGC;immunity-related GTPase family, cinema",GO:0016020//membrane,GO:0008152//metabolic process,"GO:0005525//GTP binding;GO:0016817//hydrolase activity, acting on acid anhydrides",K14140//Toxoplasmosis;K14139//Toxoplasmosis
5627,0,0,0,0,0,0,0,0,32,0,0,0,PROS1;protein S (alpha),GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0005789//endoplasmic reticulum membrane;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0042730//fibrinolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0030449//regulation of complement activation;GO:0030168//platelet activation;GO:0050900//leukocyte migration;GO:0045087//innate immune response;GO:0043687//post-translational protein modification,GO:0004866//endopeptidase inhibitor activity;GO:0005509//calcium ion binding,K03908//Complement and coagulation cascades
56270,1,0,1,26,103,0,37,126,32,148,8,1,WDR45B;WD repeat domain 45B,-,-,-,-
56271,0,20,0,6,92,16,40,32,3,0,0,0,"BEX4;brain expressed, X-linked 4",GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,K12465//Neurotrophin signaling pathway
56288,0,0,0,4,44,33,0,36,43,0,0,0,PARD3;par-3 family cell polarity regulator,GO:0005913//cell-cell adherens junction;GO:0005819//spindle;GO:0043234//protein complex;GO:0045177//apical part of cell;GO:0044295//axonal growth cone;GO:0005938//cell cortex;GO:0043025//neuronal cell body;GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0030054//cell junction;GO:0033269//internode region of axon;GO:0005829//cytosol;GO:0005923//tight junction,"GO:0045216//cell-cell junction organization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007049//cell cycle;GO:0051642//centrosome localization;GO:0007409//axonogenesis;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0006461//protein complex assembly;GO:0032970//regulation of actin filament-based process;GO:0007163//establishment or maintenance of cell polarity;GO:0090162//establishment of epithelial cell polarity;GO:0044319//wound healing, spreading of cells;GO:0031643//positive regulation of myelination;GO:0034329//cell junction assembly;GO:0022011//myelination in peripheral nervous system;GO:0003383//apical constriction;GO:0008356//asymmetric cell division;GO:0070830//tight junction assembly;GO:0006612//protein targeting to membrane;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0060341//regulation of cellular localization","GO:0005080//protein kinase C binding;GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019903//protein phosphatase binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding",K04237//Adherens junction;Neuroactive ligand-receptor interaction;Chemokine signaling pathway;Tight junction;Endocytosis
5629,0,0,0,0,9,31,14,96,50,0,5,0,PROX1;prospero homeobox 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0070365//hepatocyte differentiation;GO:0010595//positive regulation of endothelial cell migration;GO:0048845//venous blood vessel morphogenesis;GO:0097150//neuronal stem cell maintenance;GO:0007420//brain development;GO:0021516//dorsal spinal cord development;GO:0008285//negative regulation of cell proliferation;GO:1901978//positive regulation of cell cycle checkpoint;GO:0002194//hepatocyte cell migration;GO:0008284//positive regulation of cell proliferation;GO:0001822//kidney development;GO:0060414//aorta smooth muscle tissue morphogenesis;GO:0002088//lens development in camera-type eye;GO:0046619//optic placode formation involved in camera-type eye formation;GO:0001889//liver development;GO:0042752//regulation of circadian rhythm;GO:0001709//cell fate determination;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0031667//response to nutrient levels;GO:0060836//lymphatic endothelial cell differentiation;GO:0072574//hepatocyte proliferation;GO:0060412//ventricular septum morphogenesis;GO:0001946//lymphangiogenesis;GO:0045787//positive regulation of cell cycle;GO:0070858//negative regulation of bile acid biosynthetic process;GO:0060298//positive regulation of sarcomere organization;GO:0030240//skeletal muscle thin filament assembly;GO:0060042//retina morphogenesis in camera-type eye;GO:0060849//regulation of transcription involved in lymphatic endothelial cell fate commitment;GO:0030910//olfactory placode formation;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060421//positive regulation of heart growth;GO:0001938//positive regulation of endothelial cell proliferation;GO:0043049//otic placode formation;GO:0031016//pancreas development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0055005//ventricular cardiac myofibril assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000979//positive regulation of forebrain neuron differentiation;GO:0070309//lens fiber cell morphogenesis;GO:0010468//regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0045071//negative regulation of viral genome replication;GO:0060214//endocardium formation;GO:0021707//cerebellar granule cell differentiation;GO:0021542//dentate gyrus development;GO:0021915//neural tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060059//embryonic retina morphogenesis in camera-type eye;GO:2000179//positive regulation of neural precursor cell proliferation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0050692//DBD domain binding;GO:0005515//protein binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003714//transcription corepressor activity;GO:0050693//LBD domain binding,-
563,0,35,1,48,142,0,0,15,2,0,7,0,"AZGP1;alpha-2-glycoprotein 1, zinc-binding",GO:0005634//nucleus;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0042612//MHC class I protein complex,GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0071806//protein transmembrane transport;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste;GO:0001895//retina homeostasis;GO:0006955//immune response;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion,GO:0042605//peptide antigen binding;GO:0004540//ribonuclease activity;GO:0001948//glycoprotein binding;GO:0008320//protein transmembrane transporter activity,K06751//Antigen processing and presentation;Epstein-Barr virus infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Graft-versus-host disease;Viral myocarditis;Allograft rejection;Type I diabetes mellitus;HTLV-I infection;Endocytosis;Autoimmune thyroid disease;Phagosome
5630,18,0,13,0,0,0,21,0,0,232,12,1,PRPH;peripherin,GO:0044299//C-fiber;GO:0045098//type III intermediate filament;GO:0005883//neurofilament;GO:0016020//membrane;GO:0042622//photoreceptor outer segment membrane;GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,GO:0045104//intermediate filament cytoskeleton organization,GO:0005198//structural molecule activity,K07607//Amyotrophic lateral sclerosis (ALS)
56300,73,0,14,0,0,0,0,0,22,14,0,0,"IL36G;interleukin 36, gamma",GO:0005615//extracellular space,GO:0006955//immune response;GO:0032755//positive regulation of interleukin-6 production;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response,GO:0005125//cytokine activity;GO:0005149//interleukin-1 receptor binding,-
56301,2,0,0,9,0,0,36,0,47,0,22,0,"SLC7A10;solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0042942//D-serine transport;GO:0050900//leukocyte migration;GO:0015804//neutral amino acid transport;GO:0007596//blood coagulation;GO:0006811//ion transport;GO:0015825//L-serine transport;GO:0042941//D-alanine transport;GO:0055085//transmembrane transport,GO:0015194//L-serine transmembrane transporter activity;GO:0015175//neutral amino acid transmembrane transporter activity,-
56302,1,0,0,32,0,7,0,0,34,0,31,0,"TRPV5;transient receptor potential cation channel, subfamily V, member 5",GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0051262//protein tetramerization;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0006816//calcium ion transport;GO:0060402//calcium ion transport into cytosol,GO:0005516//calmodulin binding;GO:0005515//protein binding;GO:0005262//calcium channel activity,K04974//Endocrine and other factor-regulated calcium reabsorption
5631,0,0,0,20,8,16,0,0,12,0,0,0,PRPS1;phosphoribosyl pyrophosphate synthetase 1,GO:0005829//cytosol,GO:0006221//pyrimidine nucleotide biosynthetic process;GO:0007399//nervous system development;GO:0034418//urate biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0009156//ribonucleoside monophosphate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046101//hypoxanthine biosynthetic process;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0016310//phosphorylation;GO:0006164//purine nucleotide biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0008219//cell death,GO:0042803//protein homodimerization activity;GO:0004749//ribose phosphate diphosphokinase activity;GO:0000287//magnesium ion binding;GO:0016301//kinase activity;GO:0005524//ATP binding,K00948//Purine metabolism;Biosynthesis of secondary metabolites;Pentose phosphate pathway;Oxidative phosphorylation;Microbial metabolism in diverse environments;Thiamine metabolism;Metabolic pathways
56311,0,0,0,0,0,0,0,0,34,0,0,0,ANKRD7;ankyrin repeat domain 7,GO:0005634//nucleus,GO:0008584//male gonad development,-,-
56339,0,125,24,107,277,0,0,168,77,0,168,0,METTL3;methyltransferase like 3,GO:0005654//nucleoplasm;GO:0036396//MIS complex;GO:0005634//nucleus;GO:0016607//nuclear speck,GO:0061157//mRNA destabilization;GO:0019827//stem cell maintenance;GO:0007623//circadian rhythm;GO:0006397//mRNA processing;GO:0080009//mRNA methylation;GO:0010467//gene expression;GO:0001510//RNA methylation,GO:0003723//RNA binding;GO:0016422//mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,-
5634,0,23,1,3,72,3,0,0,13,113,0,0,PRPS2;phosphoribosyl pyrophosphate synthetase 2,GO:0002189//ribose phosphate diphosphokinase complex;GO:0070062//extracellular vesicular exosome,GO:0006167//AMP biosynthetic process;GO:0031100//organ regeneration;GO:0006139//nucleobase-containing compound metabolic process;GO:0016310//phosphorylation;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process,GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0019003//GDP binding;GO:0004749//ribose phosphate diphosphokinase activity;GO:0030246//carbohydrate binding;GO:0016208//AMP binding;GO:0043531//ADP binding;GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity,K00948//Pentose phosphate pathway;Oxidative phosphorylation;Microbial metabolism in diverse environments;Metabolic pathways;Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites
56341,22,0,0,0,0,0,32,0,2,0,1,0,PRMT8;protein arginine methyltransferase 8,GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005829//cytosol,"GO:0043985//histone H4-R3 methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0034969//histone arginine methylation;GO:0043393//regulation of protein binding;GO:0016571//histone methylation;GO:0019919//peptidyl-arginine methylation, to asymmetrical-dimethyl arginine",GO:0035242//protein-arginine omega-N asymmetric methyltransferase activity;GO:0008469//histone-arginine N-methyltransferase activity;GO:0044020//histone methyltransferase activity (H4-R3 specific);GO:0042802//identical protein binding;GO:0035241//protein-arginine omega-N monomethyltransferase activity;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
56344,0,0,0,0,0,0,0,0,23,129,1,0,CABP5;calcium binding protein 5,GO:0005829//cytosol,GO:0007165//signal transduction,GO:0005509//calcium ion binding,K02183//Olfactory transduction;Calcium signaling pathway;Salivary secretion;Glioma;Gastric acid secretion;Melanogenesis;Neurotrophin signaling pathway;Alzheimer's disease;Alcoholism;Pertussis;Tuberculosis;Long-term potentiation;Phosphatidylinositol signaling system;GnRH signaling pathway;Dopaminergic synapse;Insulin signaling pathway;Phototransduction;Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Vascular smooth muscle contraction;Oocyte meiosis
5635,0,0,0,5,4,0,0,0,59,0,0,0,PRPSAP1;phosphoribosyl pyrophosphate synthetase-associated protein 1,GO:0002189//ribose phosphate diphosphokinase complex,GO:0009165//nucleotide biosynthetic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0033673//negative regulation of kinase activity,GO:0004749//ribose phosphate diphosphokinase activity;GO:0000287//magnesium ion binding;GO:0019900//kinase binding;GO:0004857//enzyme inhibitor activity,K00948//Oxidative phosphorylation;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites
5636,0,0,0,0,26,0,0,138,0,0,0,0,PRPSAP2;phosphoribosyl pyrophosphate synthetase-associated protein 2,GO:0002189//ribose phosphate diphosphokinase complex,GO:0060348//bone development;GO:0006139//nucleobase-containing compound metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0043086//negative regulation of catalytic activity,GO:0000287//magnesium ion binding;GO:0004857//enzyme inhibitor activity;GO:0004749//ribose phosphate diphosphokinase activity,K00948//Metabolic pathways;Thiamine metabolism;Oxidative phosphorylation;Microbial metabolism in diverse environments;Pentose phosphate pathway;Biosynthesis of secondary metabolites;Purine metabolism
5638,0,0,0,0,1,0,80,0,23,0,0,0,PRRG1;proline rich Gla (G-carboxyglutamic acid) 1,GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,-,GO:0005509//calcium ion binding,K01314//Complement and coagulation cascades;K01320//Complement and coagulation cascades;K00522//Mineral absorption;Porphyrin and chlorophyll metabolism
5639,0,0,0,0,0,0,27,0,0,0,0,0,PRRG2;proline rich Gla (G-carboxyglutamic acid) 2,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,K01321//Complement and coagulation cascades;K01320//Complement and coagulation cascades;K01314//Complement and coagulation cascades
5641,0,0,0,0,18,0,9,0,20,0,0,678,LGMN;legumain,GO:0005770//late endosome;GO:0070062//extracellular vesicular exosome;GO:0045177//apical part of cell;GO:0005764//lysosome;GO:0043202//lysosomal lumen,GO:0008202//steroid metabolic process;GO:1901185//negative regulation of ERBB signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0040015//negative regulation of multicellular organism growth;GO:0032801//receptor catabolic process;GO:0010447//response to acidic pH;GO:0003014//renal system process;GO:0045087//innate immune response;GO:0043524//negative regulation of neuron apoptotic process;GO:0042359//vitamin D metabolic process;GO:0044281//small molecule metabolic process,GO:0004197//cysteine-type endopeptidase activity;GO:0008233//peptidase activity,K01369//Antigen processing and presentation;Lysosome
56413,0,22,0,2,48,14,0,0,16,0,12,0,LTB4R2;leukotriene B4 receptor 2,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0007194//negative regulation of adenylate cyclase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0051546//keratinocyte migration;GO:0006935//chemotaxis,GO:0004974//leukotriene receptor activity;GO:0001632//leukotriene B4 receptor activity,K04297//Calcium signaling pathway;Neuroactive ligand-receptor interaction
5644,0,0,0,0,0,0,0,0,0,2,4,0,"PRSS1;protease, serine, 1 (trypsin 1)",GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region,GO:0006766//vitamin metabolic process;GO:0006508//proteolysis;GO:0009235//cobalamin metabolic process;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0007586//digestion;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process,GO:0046872//metal ion binding;GO:0004252//serine-type endopeptidase activity,K01312//Neuroactive ligand-receptor interaction;Influenza A;Protein digestion and absorption;Pancreatic secretion
5646,0,0,0,0,0,0,12,0,1,0,0,0,"PRSS3;protease, serine, 3",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0006766//vitamin metabolic process;GO:0031638//zymogen activation;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0007586//digestion;GO:0009235//cobalamin metabolic process;GO:0043542//endothelial cell migration;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0008236//serine-type peptidase activity;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004252//serine-type endopeptidase activity,K01312//Influenza A;Neuroactive ligand-receptor interaction;Protein digestion and absorption;Pancreatic secretion
56474,219,34,0,29,78,0,23,0,28,0,6,0,CTPS2;CTP synthase 2,GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006541//glutamine metabolic process;GO:0044210//'de novo' CTP biosynthetic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0006220//pyrimidine nucleotide metabolic process,GO:0005524//ATP binding;GO:0003883//CTP synthase activity,K01937//Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
56475,1,0,0,0,0,0,0,0,5,0,0,0,"RPRM;reprimo, TP53 dependent G2 arrest mediator candidate",GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0007050//cell cycle arrest;GO:0007346//regulation of mitotic cell cycle,-,K10128//p53 signaling pathway
56478,0,60,0,20,13,37,0,0,11,0,11,0,EIF4ENIF1;eukaryotic translation initiation factor 4E nuclear import factor 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0016020//membrane;GO:0016607//nuclear speck;GO:0016605//PML body,GO:0015031//protein transport,GO:0008565//protein transporter activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
56479,136,0,0,0,0,0,41,104,8,0,10,301,"KCNQ5;potassium voltage-gated channel, KQT-like subfamily, member 5",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex,GO:0006461//protein complex assembly;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport,GO:0005242//inward rectifier potassium channel activity;GO:0005251//delayed rectifier potassium channel activity,K04930//Cholinergic synapse
5648,23,0,51,0,0,27,49,35,99,66,14,0,MASP1;mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor),GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0045087//innate immune response;GO:0006956//complement activation;GO:0045916//negative regulation of complement activation;GO:0001867//complement activation, lectin pathway;GO:0006508//proteolysis",GO:0008233//peptidase activity;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K03992//Staphylococcus aureus infection;Complement and coagulation cascades
5649,122,40,89,123,131,9,49,99,128,2,144,0,RELN;reelin,GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0030425//dendrite;GO:0005615//extracellular space,"GO:0048265//response to pain;GO:0006508//proteolysis;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:2000969//positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:1902078//positive regulation of lateral motor column neuron migration;GO:0097114//N-methyl-D-aspartate receptor clustering;GO:0010001//glial cell differentiation;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0010976//positive regulation of neuron projection development;GO:0045860//positive regulation of protein kinase activity;GO:0097477//lateral motor column neuron migration;GO:0021517//ventral spinal cord development;GO:0007616//long-term memory;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007411//axon guidance;GO:0000904//cell morphogenesis involved in differentiation;GO:0090129//positive regulation of synapse maturation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0007155//cell adhesion;GO:0032793//positive regulation of CREB transcription factor activity;GO:0021819//layer formation in cerebral cortex;GO:0038026//reelin-mediated signaling pathway;GO:0001764//neuron migration;GO:0050804//regulation of synaptic transmission;GO:0016358//dendrite development;GO:0050795//regulation of behavior;GO:0021511//spinal cord patterning;GO:0032008//positive regulation of TOR signaling;GO:0097119//postsynaptic density protein 95 clustering;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0097120//receptor localization to synapse;GO:0008306//associative learning;GO:0007417//central nervous system development;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0007420//brain development;GO:1900273//positive regulation of long-term synaptic potentiation;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0021766//hippocampus development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0021800//cerebral cortex tangential migration",GO:0070325//lipoprotein particle receptor binding;GO:0070326//very-low-density lipoprotein particle receptor binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0008236//serine-type peptidase activity,K06249//Focal adhesion;ECM-receptor interaction
5650,234,0,0,0,0,0,11,0,0,0,0,0,KLK7;kallikrein-related peptidase 7,GO:0005576//extracellular region;GO:0097209//epidermal lamellar body,GO:0006508//proteolysis;GO:0008544//epidermis development;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly,GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,-
5651,96,0,0,0,0,57,1,0,54,167,0,0,"TMPRSS15;transmembrane protease, serine 15",GO:0016021//integral component of membrane;GO:0005903//brush border,GO:0006898//receptor-mediated endocytosis;GO:0006508//proteolysis,GO:0005044//scavenger receptor activity;GO:0004252//serine-type endopeptidase activity,-
5652,0,0,35,0,0,0,0,0,12,0,0,0,"PRSS8;protease, serine, 8",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0010765//positive regulation of sodium ion transport,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,-
56521,0,0,0,0,28,0,0,0,0,0,0,0,"DNAJC12;DnaJ (Hsp40) homolog, subfamily C, member 12",-,-,-,-
5653,45,0,0,0,0,5,0,0,14,0,0,0,KLK6;kallikrein-related peptidase 6,GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005615//extracellular space,GO:0042982//amyloid precursor protein metabolic process;GO:0042552//myelination;GO:0030574//collagen catabolic process;GO:0007417//central nervous system development;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0045595//regulation of cell differentiation;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0042246//tissue regeneration;GO:0042445//hormone metabolic process;GO:0070997//neuron death;GO:0009611//response to wounding;GO:0010975//regulation of neuron projection development,GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity,-
5654,0,12,0,0,0,0,1,0,41,0,0,0,HTRA1;HtrA serine peptidase 1,GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0030514//negative regulation of BMP signaling pathway;GO:0006508//proteolysis;GO:0001558//regulation of cell growth;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding,-
56547,0,0,0,0,0,0,0,0,17,0,0,0,MMP26;matrix metallopeptidase 26,GO:0005578//proteinaceous extracellular matrix,GO:0030574//collagen catabolic process;GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,K04257//Olfactory transduction
56548,68,29,0,0,0,0,15,0,36,0,33,292,CHST7;carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006790//sulfur compound metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0006044//N-acetylglucosamine metabolic process;GO:0005976//polysaccharide metabolic process,GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008459//chondroitin 6-sulfotransferase activity,K04743//Glycosaminoglycan biosynthesis - chondroitin sulfate
5655,0,0,0,0,0,0,0,0,0,143,0,135,KLK10;kallikrein-related peptidase 10,GO:0005576//extracellular region,GO:0007049//cell cycle;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity,-
5657,0,0,0,0,0,1,0,0,24,0,0,0,PRTN3;proteinase 3,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031012//extracellular matrix,GO:0006508//proteolysis;GO:0097029//mature dendritic cell differentiation;GO:0050765//negative regulation of phagocytosis;GO:0030574//collagen catabolic process;GO:0008284//positive regulation of cell proliferation,GO:0004252//serine-type endopeptidase activity;GO:0019899//enzyme binding;GO:0008236//serine-type peptidase activity,-
566,0,0,0,0,0,0,0,76,19,0,19,0,AZU1;azurocidin 1,GO:0042582//azurophil granule;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0008347//glial cell migration;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0050829//defense response to Gram-negative bacterium;GO:0042117//monocyte activation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0050930//induction of positive chemotaxis;GO:0043114//regulation of vascular permeability;GO:0050725//positive regulation of interleukin-1 beta biosynthetic process;GO:0050766//positive regulation of phagocytosis;GO:0045785//positive regulation of cell adhesion;GO:0001774//microglial cell activation;GO:0006954//inflammatory response;GO:0050754//positive regulation of fractalkine biosynthetic process;GO:0045123//cellular extravasation;GO:0048246//macrophage chemotaxis;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0015643//toxic substance binding;GO:0008201//heparin binding,K01327//Systemic lupus erythematosus;Transcriptional misregulation in cancer
5660,0,24,0,8,44,0,32,32,0,0,0,0,PSAP;prosaposin,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane,GO:0002576//platelet degranulation;GO:0071310//cellular response to organic substance;GO:0019216//regulation of lipid metabolic process;GO:0006869//lipid transport;GO:0043408//regulation of MAPK cascade;GO:0006687//glycosphingolipid metabolic process;GO:0060736//prostate gland growth;GO:0043085//positive regulation of catalytic activity;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0007596//blood coagulation;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0030168//platelet activation,GO:0008289//lipid binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding,K12382//Lysosome
56603,174,0,0,0,0,0,24,57,56,1,11,0,"CYP26B1;cytochrome P450, family 26, subfamily B, polypeptide 1",GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0061436//establishment of skin barrier;GO:0070268//cornification;GO:0007283//spermatogenesis;GO:0071300//cellular response to retinoic acid;GO:0001709//cell fate determination;GO:0060349//bone morphogenesis;GO:2001037//positive regulation of tongue muscle cell differentiation;GO:0006766//vitamin metabolic process;GO:0055114//oxidation-reduction process;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043587//tongue morphogenesis;GO:0009954//proximal/distal pattern formation;GO:0010628//positive regulation of gene expression;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0007140//male meiosis;GO:0048384//retinoic acid receptor signaling pathway;GO:0030326//embryonic limb morphogenesis;GO:0034653//retinoic acid catabolic process,GO:0005506//iron ion binding;GO:0008401//retinoic acid 4-hydroxylase activity;GO:0001972//retinoic acid binding;GO:0020037//heme binding,K12664//Retinol metabolism
56605,14,0,0,7,28,25,5,0,9,0,0,0,ERO1LB;ERO1-like beta (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,GO:0030070//insulin processing;GO:0055114//oxidation-reduction process;GO:0042593//glucose homeostasis;GO:0030198//extracellular matrix organization;GO:0006457//protein folding;GO:0022417//protein maturation by protein folding;GO:0045454//cell redox homeostasis,"GO:0003756//protein disulfide isomerase activity;GO:0051082//unfolded protein binding;GO:0015035//protein disulfide oxidoreductase activity;GO:0016491//oxidoreductase activity;GO:0016671//oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor;GO:0005515//protein binding",K10976//Protein processing in endoplasmic reticulum
56606,0,0,0,0,0,0,0,0,43,265,13,0,"SLC2A9;solute carrier family 2 (facilitated glucose transporter), member 9",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005635//nuclear envelope;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0015992//proton transport;GO:0015758//glucose transport;GO:0046415//urate metabolic process,GO:0005355//glucose transmembrane transporter activity;GO:0005351//sugar:proton symporter activity,-
56616,0,1,0,1,23,21,22,56,34,0,0,0,"DIABLO;diablo, IAP-binding mitochondrial protein",GO:0005758//mitochondrial intermembrane space;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0006915//apoptotic process;GO:0051402//neuron apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0043065//positive regulation of apoptotic process;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors,GO:0005515//protein binding,-
5662,0,0,0,0,0,50,0,1,12,0,0,0,PSD;pleckstrin and Sec7 domain containing,GO:0005802//trans-Golgi network;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0032012//regulation of ARF protein signal transduction;GO:0030182//neuron differentiation;GO:0016192//vesicle-mediated transport,GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0005543//phospholipid binding,K12494//Endocytosis
56623,2,0,0,0,0,0,32,64,36,143,3,0,"INPP5E;inositol polyphosphate-5-phosphatase, 72 kDa",GO:0005930//axoneme;GO:0005856//cytoskeleton;GO:0032580//Golgi cisterna membrane;GO:0005829//cytosol,GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0046855//inositol phosphate dephosphorylation;GO:0044281//small molecule metabolic process;GO:0006644//phospholipid metabolic process,"GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",K01099//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
56624,0,0,0,0,11,0,0,0,18,0,0,0,ASAH2;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006915//apoptotic process;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0006687//glycosphingolipid metabolic process;GO:0006672//ceramide metabolic process,GO:0017040//ceramidase activity,K12349//Metabolic pathways;Sphingolipid metabolism
5663,0,0,0,1,0,0,0,0,0,0,0,0,PSEN1;presenilin 1,GO:0043198//dendritic shaft;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0005813//centrosome;GO:0031965//nuclear membrane;GO:0035253//ciliary rootlet;GO:0031410//cytoplasmic vesicle;GO:0005743//mitochondrial inner membrane;GO:0005791//rough endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005640//nuclear outer membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0000776//kinetochore;GO:0031594//neuromuscular junction;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005938//cell cortex;GO:0030426//growth cone;GO:0005765//lysosomal membrane;GO:0030018//Z disc;GO:0070765//gamma-secretase complex;GO:0030424//axon;GO:0005790//smooth endoplasmic reticulum;GO:0005887//integral component of plasma membrane,"GO:0001764//neuron migration;GO:0070588//calcium ion transmembrane transport;GO:0009791//post-embryonic development;GO:0007613//memory;GO:0000186//activation of MAPKK activity;GO:0015871//choline transport;GO:0048854//brain morphogenesis;GO:0050820//positive regulation of coagulation;GO:0016337//single organismal cell-cell adhesion;GO:0030326//embryonic limb morphogenesis;GO:0002573//myeloid leukocyte differentiation;GO:0001568//blood vessel development;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042987//amyloid precursor protein catabolic process;GO:0043065//positive regulation of apoptotic process;GO:0034205//beta-amyloid formation;GO:0006486//protein glycosylation;GO:0016485//protein processing;GO:0043393//regulation of protein binding;GO:0006974//cellular response to DNA damage stimulus;GO:0048705//skeletal system morphogenesis;GO:0006509//membrane protein ectodomain proteolysis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002286//T cell activation involved in immune response;GO:0050771//negative regulation of axonogenesis;GO:0001708//cell fate specification;GO:0042325//regulation of phosphorylation;GO:0030198//extracellular matrix organization;GO:0051563//smooth endoplasmic reticulum calcium ion homeostasis;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0001921//positive regulation of receptor recycling;GO:0006979//response to oxidative stress;GO:0050852//T cell receptor signaling pathway;GO:0000045//autophagic vacuole assembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0042640//anagen;GO:0035556//intracellular signal transduction;GO:0021870//Cajal-Retzius cell differentiation;GO:0050435//beta-amyloid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0050673//epithelial cell proliferation;GO:0015813//L-glutamate transport;GO:0048666//neuron development;GO:0021795//cerebral cortex cell migration;GO:0043589//skin morphogenesis;GO:0043085//positive regulation of catalytic activity;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0060075//regulation of resting membrane potential;GO:0022617//extracellular matrix disassembly;GO:0007219//Notch signaling pathway;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0016080//synaptic vesicle targeting;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0051402//neuron apoptotic process;GO:0001947//heart looping;GO:0048167//regulation of synaptic plasticity;GO:0060070//canonical Wnt signaling pathway;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0015031//protein transport;GO:0007220//Notch receptor processing;GO:0006839//mitochondrial transport;GO:0021904//dorsal/ventral neural tube patterning;GO:0048538//thymus development;GO:0001756//somitogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043406//positive regulation of MAP kinase activity",GO:0008013//beta-catenin binding;GO:0004190//aspartic-type endopeptidase activity;GO:0030165//PDZ domain binding;GO:0004175//endopeptidase activity;GO:0045296//cadherin binding;GO:0005262//calcium channel activity;GO:0005515//protein binding,K04505//Alzheimer's disease;Neurotrophin signaling pathway;Wnt signaling pathway;Notch signaling pathway
5664,0,0,0,0,10,0,12,0,0,83,9,0,PSEN2;presenilin 2,GO:0035253//ciliary rootlet;GO:0043234//protein complex;GO:0016324//apical plasma membrane;GO:0043025//neuronal cell body;GO:0005813//centrosome;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0043198//dendritic shaft;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005743//mitochondrial inner membrane;GO:0030018//Z disc;GO:0030426//growth cone;GO:0005938//cell cortex;GO:0005765//lysosomal membrane;GO:0009986//cell surface;GO:0036064//ciliary basal body;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0000776//kinetochore;GO:0031594//neuromuscular junction;GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0005637//nuclear inner membrane,GO:0042640//anagen;GO:0035556//intracellular signal transduction;GO:0050820//positive regulation of coagulation;GO:0050435//beta-amyloid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0006816//calcium ion transport;GO:0032091//negative regulation of protein binding;GO:0031333//negative regulation of protein complex assembly;GO:0001933//negative regulation of protein phosphorylation;GO:0048854//brain morphogenesis;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0030326//embryonic limb morphogenesis;GO:0060048//cardiac muscle contraction;GO:0002573//myeloid leukocyte differentiation;GO:0097190//apoptotic signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0007613//memory;GO:0030900//forebrain development;GO:0002286//T cell activation involved in immune response;GO:0015031//protein transport;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0007220//Notch receptor processing;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0048167//regulation of synaptic plasticity;GO:0006509//membrane protein ectodomain proteolysis;GO:0001756//somitogenesis;GO:0048286//lung alveolus development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0001708//cell fate specification;GO:0021904//dorsal/ventral neural tube patterning;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0048538//thymus development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0031293//membrane protein intracellular domain proteolysis;GO:0042987//amyloid precursor protein catabolic process;GO:0043085//positive regulation of catalytic activity;GO:0001666//response to hypoxia;GO:0007219//Notch signaling pathway;GO:0016485//protein processing;GO:0040011//locomotion,GO:0005515//protein binding;GO:0004190//aspartic-type endopeptidase activity;GO:0004175//endopeptidase activity,K04522//Neurotrophin signaling pathway;Alzheimer's disease;Notch signaling pathway
56647,1,163,154,288,377,13,0,0,9,0,437,29,BCCIP;BRCA2 and CDKN1A interacting protein,GO:0005634//nucleus;GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex,GO:0006281//DNA repair;GO:0007049//cell cycle;GO:0061101//neuroendocrine cell differentiation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019207//kinase regulator activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
56648,0,0,42,0,0,0,55,0,43,0,2,0,EIF5A2;eukaryotic translation initiation factor 5A2,GO:0005829//cytosol;GO:0005643//nuclear pore;GO:0005789//endoplasmic reticulum membrane,GO:0015031//protein transport;GO:0010509//polyamine homeostasis;GO:0045901//positive regulation of translational elongation;GO:0007283//spermatogenesis;GO:0044267//cellular protein metabolic process;GO:0008612//peptidyl-lysine modification to peptidyl-hypusine;GO:0045905//positive regulation of translational termination;GO:0006452//translational frameshifting;GO:0051028//mRNA transport;GO:0043687//post-translational protein modification;GO:0008284//positive regulation of cell proliferation,GO:0005515//protein binding;GO:0043022//ribosome binding;GO:0003746//translation elongation factor activity,-
56649,0,0,35,0,0,0,15,1,14,135,30,0,"TMPRSS4;transmembrane protease, serine 4",GO:0016021//integral component of membrane,GO:0006898//receptor-mediated endocytosis;GO:0006508//proteolysis,GO:0005044//scavenger receptor activity;GO:0004252//serine-type endopeptidase activity,K09635//Influenza A
56650,96,1,0,0,29,0,9,0,6,0,0,0,CLDND1;claudin domain containing 1,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,-,-,-
56652,0,0,0,0,22,0,27,65,25,134,0,84,C10orf2;chromosome 10 open reading frame 2,GO:0042645//mitochondrial nucleoid,GO:0006390//transcription from mitochondrial promoter;GO:0008219//cell death;GO:0006264//mitochondrial DNA replication;GO:0051260//protein homooligomerization;GO:0034214//protein hexamerization;GO:0006268//DNA unwinding involved in DNA replication,GO:0003697//single-stranded DNA binding;GO:0043139//5'-3' DNA helicase activity;GO:0005524//ATP binding;GO:0002020//protease binding,-
56654,0,1,1,5,10,0,4,0,29,0,0,0,"NPDC1;neural proliferation, differentiation and control, 1",GO:0016021//integral component of membrane,-,-,-
56656,0,0,0,0,0,0,0,6,22,0,0,0,"OR2S2;olfactory receptor, family 2, subfamily S, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
56659,90,0,0,0,0,0,0,0,49,0,0,0,"KCNK13;potassium channel, subfamily K, member 13",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005267//potassium channel activity;GO:0005244//voltage-gated ion channel activity,-
56660,0,0,0,0,0,0,0,0,0,0,1,0,"KCNK12;potassium channel, subfamily K, member 12",GO:0016021//integral component of membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,-
56662,0,0,0,0,0,0,0,0,2,0,0,0,VTRNA1-3;vault RNA 1-3,-,-,-,-
56666,0,0,0,0,0,22,0,55,52,0,0,0,PANX2;pannexin 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005921//gap junction,GO:0002931//response to ischemia;GO:0006811//ion transport;GO:0034214//protein hexamerization;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission,GO:0055077//gap junction hemi-channel activity,-
56667,0,0,0,0,0,21,0,0,14,0,0,89,"MUC13;mucin 13, cell surface associated",GO:0016324//apical plasma membrane;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen,GO:0030277//maintenance of gastrointestinal epithelium;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0042803//protein homodimerization activity,K06588//Focal adhesion;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Phagosome;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC)
56670,0,0,0,0,0,0,0,0,35,0,0,0,SUCNR1;succinate receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
56672,0,0,0,0,0,0,0,0,9,0,0,0,AKIP1;A kinase (PRKA) interacting protein 1,GO:0005634//nucleus,GO:0034446//substrate adhesion-dependent cell spreading,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
56673,0,0,0,0,18,12,0,0,21,0,0,0,C11orf16;chromosome 11 open reading frame 16,-,-,-,-
56674,0,95,26,40,112,0,22,78,31,0,121,1,"TMEM9B;TMEM9 domain family, member B",GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0004871//signal transducer activity,-
56675,0,0,0,0,0,7,4,5,1,0,1,0,NRIP3;nuclear receptor interacting protein 3,-,GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity,-
56681,6,84,0,1,127,0,52,0,15,56,36,0,"SAR1A;secretion associated, Ras related GTPase 1A",GO:0005794//Golgi apparatus;GO:0016529//sarcoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0006886//intracellular protein transport;GO:0016192//vesicle-mediated transport;GO:1901303//negative regulation of cargo loading into COPII-coated vesicle,GO:0005525//GTP binding,K07953//Legionellosis;Protein processing in endoplasmic reticulum
56683,0,0,42,16,4,0,0,0,0,0,0,0,C21orf59;chromosome 21 open reading frame 59,GO:0005634//nucleus;GO:0005829//cytosol,-,-,-
567,0,71,1,90,225,13,0,0,5,0,0,0,B2M;beta-2-microglobulin,GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0031905//early endosome lumen;GO:0031901//early endosome membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0042612//MHC class I protein complex;GO:0005794//Golgi apparatus;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane,"GO:0002480//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent;GO:0016032//viral process;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050776//regulation of immune response;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0002237//response to molecule of bacterial origin;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0033077//T cell differentiation in thymus;GO:0001895//retina homeostasis;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0042493//response to drug;GO:0042026//protein refolding;GO:0046686//response to cadmium ion",GO:0005515//protein binding;GO:0042802//identical protein binding,K08055//Antigen processing and presentation
5670,0,0,0,0,0,0,1,0,0,0,0,0,PSG2;pregnancy specific beta-1-glycoprotein 2,GO:0005576//extracellular region,GO:0007565//female pregnancy;GO:0016477//cell migration,-,-
56704,16,0,0,0,0,31,0,0,35,0,0,0,JPH1;junctophilin 1,GO:0030018//Z disc;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0030314//junctional membrane complex;GO:0005886//plasma membrane,GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0007517//muscle organ development;GO:0060402//calcium ion transport into cytosol,GO:0008307//structural constituent of muscle,K04575//Amyotrophic lateral sclerosis (ALS)
5671,0,0,0,0,0,1,38,54,0,0,2,0,PSG3;pregnancy specific beta-1-glycoprotein 3,GO:0005576//extracellular region,GO:0007565//female pregnancy;GO:0006952//defense response,-,-
5672,0,0,0,0,0,0,28,0,0,0,0,0,PSG4;pregnancy specific beta-1-glycoprotein 4,GO:0070062//extracellular vesicular exosome,GO:0007565//female pregnancy,-,-
5673,0,0,0,0,0,0,0,0,16,0,0,0,PSG5;pregnancy specific beta-1-glycoprotein 5,GO:0005576//extracellular region,GO:0007565//female pregnancy,GO:0005515//protein binding,-
56731,0,0,2,1,20,3,0,32,12,0,8,0,SLC2A4RG;SLC2A4 regulator,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
5675,0,0,14,0,0,10,22,0,8,0,5,0,PSG6;pregnancy specific beta-1-glycoprotein 6,GO:0005576//extracellular region,GO:0007565//female pregnancy,-,-
56751,0,0,0,0,0,1,15,0,18,0,0,0,BARHL1;BarH-like homeobox 1,GO:0005634//nucleus,"GO:0043524//negative regulation of neuron apoptotic process;GO:0001764//neuron migration;GO:0007605//sensory perception of sound;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0030901//midbrain development",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0043565//sequence-specific DNA binding,-
5676,0,0,0,0,0,0,0,0,9,0,0,0,PSG7;pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene),GO:0005576//extracellular region,GO:0007565//female pregnancy,-,-
56776,0,0,0,0,0,21,12,0,40,199,0,0,FMN2;formin 2,GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005730//nucleolus;GO:0005819//spindle;GO:0005938//cell cortex;GO:0005902//microvillus;GO:0030659//cytoplasmic vesicle membrane;GO:0005886//plasma membrane,GO:0071456//cellular response to hypoxia;GO:0070649//formin-nucleated actin cable assembly;GO:0046907//intracellular transport;GO:0016192//vesicle-mediated transport;GO:0006974//cellular response to DNA damage stimulus;GO:0015031//protein transport;GO:0043066//negative regulation of apoptotic process;GO:0048477//oogenesis;GO:0007275//multicellular organismal development;GO:0042177//negative regulation of protein catabolic process;GO:0035556//intracellular signal transduction;GO:0051758//homologous chromosome movement towards spindle pole involved in homologous chromosome segregation;GO:0051295//establishment of meiotic spindle localization;GO:0040038//polar body extrusion after meiotic divisions,GO:0003779//actin binding,K02184//Dorso-ventral axis formation
5680,0,0,0,0,0,0,11,0,15,0,11,0,PSG11;pregnancy specific beta-1-glycoprotein 11,GO:0005576//extracellular region,GO:0007565//female pregnancy,-,-
5681,19,0,1,0,42,17,11,70,34,0,0,0,PSKH1;protein serine kinase H1,GO:0016607//nuclear speck;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005815//microtubule organizing center;GO:0005789//endoplasmic reticulum membrane,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
5682,0,2,0,16,22,0,26,0,27,0,21,0,"PSMA1;proteasome (prosome, macropain) subunit, alpha type, 1","GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005813//centrosome;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005839//proteasome core complex;GO:0005844//polysome;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus","GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0044281//small molecule metabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0006915//apoptotic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity,K02725//Proteasome
56829,19,0,59,10,52,0,2,0,67,179,0,0,"ZC3HAV1;zinc finger CCCH-type, antiviral 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0009615//response to virus;GO:0008152//metabolic process;GO:0045071//negative regulation of viral genome replication;GO:0032728//positive regulation of interferon-beta production;GO:0061014//positive regulation of mRNA catabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032727//positive regulation of interferon-alpha production;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0051607//defense response to virus;GO:0045087//innate immune response,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
5683,0,0,1,33,55,0,0,24,16,0,0,0,"PSMA2;proteasome (prosome, macropain) subunit, alpha type, 2","GO:0005829//cytosol;GO:0005634//nucleus;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0000932//cytoplasmic mRNA processing body","GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0009615//response to virus;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02726//Proteasome
56832,0,0,0,0,0,0,0,0,6,0,0,0,"IFNK;interferon, kappa",GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0002250//adaptive immune response;GO:0002323//natural killer cell activation involved in immune response;GO:0045089//positive regulation of innate immune response;GO:0043330//response to exogenous dsRNA;GO:0002286//T cell activation involved in immune response;GO:0008285//negative regulation of cell proliferation;GO:0009615//response to virus;GO:0033141//positive regulation of peptidyl-serine phosphorylation of STAT protein;GO:0042100//B cell proliferation;GO:0045087//innate immune response;GO:0006355//regulation of transcription, DNA-templated;GO:0045343//regulation of MHC class I biosynthetic process;GO:0006959//humoral immune response;GO:0030101//natural killer cell activation;GO:0019221//cytokine-mediated signaling pathway;GO:0030183//B cell differentiation;GO:0051607//defense response to virus",GO:0005125//cytokine activity;GO:0005132//type I interferon receptor binding,K05441//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;RIG-I-like receptor signaling pathway
56833,0,41,0,16,20,9,10,110,41,0,24,0,SLAMF8;SLAM family member 8,GO:0016021//integral component of membrane,GO:0043549//regulation of kinase activity;GO:0090383//phagosome acidification;GO:0035690//cellular response to drug;GO:0033860//regulation of NAD(P)H oxidase activity;GO:0042742//defense response to bacterium,GO:0004872//receptor activity,K06479//Natural killer cell mediated cytotoxicity;K06536//Measles
56834,0,489,76,354,574,0,0,245,41,0,447,0,GPR137;G protein-coupled receptor 137,GO:0016021//integral component of membrane,-,-,-
5684,0,32,0,29,39,0,0,0,7,0,0,0,"PSMA3;proteasome (prosome, macropain) subunit, alpha type, 3","GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005839//proteasome core complex;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005634//nucleus","GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02727//Proteasome
56848,0,0,0,0,0,6,0,0,25,0,0,0,SPHK2;sphingosine kinase 2,GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0005829//cytosol,GO:0001568//blood vessel development;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008284//positive regulation of cell proliferation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0006669//sphinganine-1-phosphate biosynthetic process;GO:0007420//brain development;GO:0043066//negative regulation of apoptotic process;GO:0006665//sphingolipid metabolic process;GO:0008283//cell proliferation;GO:0046834//lipid phosphorylation;GO:0006670//sphingosine metabolic process,GO:0017050//D-erythro-sphingosine kinase activity;GO:0005515//protein binding;GO:0008481//sphinganine kinase activity;GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0017016//Ras GTPase binding;GO:0005524//ATP binding,K04718//Metabolic pathways;Fc gamma R-mediated phagocytosis;Tuberculosis;Calcium signaling pathway;VEGF signaling pathway;Sphingolipid metabolism
5685,0,18,2,43,143,1,0,0,18,0,7,0,"PSMA4;proteasome (prosome, macropain) subunit, alpha type, 4","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0000932//cytoplasmic mRNA processing body;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005839//proteasome core complex;GO:0070062//extracellular vesicular exosome","GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02728//Proteasome
56850,0,12,0,0,34,0,12,0,9,0,12,0,GRIPAP1;GRIP1 associated protein 1,GO:0072562//blood microparticle;GO:0005769//early endosome,-,-,-
56851,0,0,0,0,22,7,0,0,0,0,0,0,EMC7;ER membrane protein complex subunit 7,GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
56852,0,0,1,22,61,0,0,55,34,0,0,0,RAD18;RAD18 homolog (S. cerevisiae),GO:0000785//chromatin;GO:0005634//nucleus;GO:0005657//replication fork;GO:0001741//XY body,GO:0009411//response to UV;GO:0045910//negative regulation of DNA recombination;GO:0007283//spermatogenesis;GO:0006281//DNA repair;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0031593//polyubiquitin binding;GO:0008270//zinc ion binding;GO:0000403//Y-form DNA binding;GO:0003684//damaged DNA binding,-
56853,0,0,0,0,0,0,0,31,9,0,13,0,"CELF4;CUGBP, Elav-like family member 4",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000380//alternative mRNA splicing, via spliceosome;GO:0090394//negative regulation of excitatory postsynaptic membrane potential;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0009790//embryo development;GO:0007281//germ cell development;GO:0006376//mRNA splice site selection;GO:0017148//negative regulation of translation","GO:0000900//translation repressor activity, nucleic acid binding;GO:0000166//nucleotide binding;GO:0042835//BRE binding;GO:0003729//mRNA binding",-
5686,6,1,0,2,78,14,0,0,6,0,0,0,"PSMA5;proteasome (prosome, macropain) subunit, alpha type, 5","GO:0019773//proteasome core complex, alpha-subunit complex;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus","GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02729//Proteasome
5687,0,68,2,59,203,0,20,0,0,0,0,0,"PSMA6;proteasome (prosome, macropain) subunit, alpha type, 6","GO:0005829//cytosol;GO:0005634//nucleus;GO:0030017//sarcomere;GO:0016363//nuclear matrix;GO:0030016//myofibril;GO:0070062//extracellular vesicular exosome;GO:0005844//polysome;GO:0005839//proteasome core complex;GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0000502//proteasome complex;GO:0005654//nucleoplasm","GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0000209//protein polyubiquitination;GO:0050727//regulation of inflammatory response;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression",GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity;GO:0051059//NF-kappaB binding;GO:0035639//purine ribonucleoside triphosphate binding;GO:0004175//endopeptidase activity;GO:0003723//RNA binding,K02730//Proteasome
5688,0,4,1,30,11,20,0,0,17,0,0,0,"PSMA7;proteasome (prosome, macropain) subunit, alpha type, 7","GO:0019773//proteasome core complex, alpha-subunit complex;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005634//nucleus","GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process",GO:0042802//identical protein binding;GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02731//Proteasome
56882,0,36,1,42,102,0,0,0,37,0,0,0,CDC42SE1;CDC42 small effector 1,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0008360//regulation of cell shape;GO:0043086//negative regulation of catalytic activity;GO:0006909//phagocytosis,GO:0005095//GTPase inhibitor activity,-
56884,0,0,0,0,0,33,30,0,23,74,0,0,FSTL5;follistatin-like 5,GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,K06766//Cell adhesion molecules (CAMs)
56886,64,0,0,0,31,11,43,0,86,4,6,0,UGGT1;UDP-glucose glycoprotein glucosyltransferase 1,GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0043687//post-translational protein modification;GO:0097359//UDP-glucosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0051082//unfolded protein binding;GO:0003980//UDP-glucose:glycoprotein glucosyltransferase activity,K11718//Protein processing in endoplasmic reticulum
56888,0,24,1,40,123,32,1,1,74,0,2,0,KCMF1;potassium channel modulatory factor 1,-,GO:0008152//metabolic process,GO:0016874//ligase activity;GO:0008270//zinc ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
56889,0,6,29,88,144,14,19,55,38,0,0,0,TM9SF3;transmembrane 9 superfamily member 3,GO:0016021//integral component of membrane,-,-,-
5689,0,0,0,12,32,0,0,0,17,0,19,0,"PSMB1;proteasome (prosome, macropain) subunit, beta type, 1",GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex,"GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0044281//small molecule metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02732//Proteasome
56890,115,0,0,0,20,101,41,0,26,0,5,0,MDM1;Mdm1 nuclear protein homolog (mouse),GO:0005634//nucleus,GO:0060041//retina development in camera-type eye,-,K03995//Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus
56891,0,0,0,13,0,0,0,0,12,0,7,0,"LGALS14;lectin, galactoside-binding, soluble, 14",GO:0005634//nucleus,GO:0006915//apoptotic process,GO:0030246//carbohydrate binding,-
56892,0,0,0,9,25,0,0,0,0,0,0,0,C8orf4;chromosome 8 open reading frame 4,-,GO:0006915//apoptotic process,-,-
56893,0,10,0,13,28,0,31,1,13,0,0,0,UBQLN4;ubiquilin 4,GO:0031595//nuclear proteasome complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0031597//cytosolic proteasome complex;GO:0005789//endoplasmic reticulum membrane,GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0042802//identical protein binding;GO:0031593//polyubiquitin binding;GO:0005515//protein binding,K04523//Protein processing in endoplasmic reticulum
56894,4,10,0,0,22,0,30,0,117,0,4,24,AGPAT3;1-acylglycerol-3-phosphate O-acyltransferase 3,GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane,GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008654//phospholipid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13523//Metabolic pathways;Glycerolipid metabolism;Glycerophospholipid metabolism
56895,0,0,0,0,16,0,17,62,16,0,25,0,AGPAT4;1-acylglycerol-3-phosphate O-acyltransferase 4,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0008654//phospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process,GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13523//Metabolic pathways;Glycerolipid metabolism;Glycerophospholipid metabolism
56896,0,0,0,0,2,0,0,0,49,0,9,0,DPYSL5;dihydropyrimidinase-like 5,GO:0030425//dendrite;GO:0005829//cytosol;GO:0043025//neuronal cell body,GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0007411//axon guidance;GO:0006208//pyrimidine nucleobase catabolic process,"GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides",K07529//Axon guidance
56897,1,13,0,9,16,15,4,2,18,31,8,0,WRNIP1;Werner helicase interacting protein 1,GO:0016020//membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0006260//DNA replication;GO:0006200//ATP catabolic process;GO:0000731//DNA synthesis involved in DNA repair,GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
56898,0,0,0,0,0,0,0,0,12,0,0,0,"BDH2;3-hydroxybutyrate dehydrogenase, type 2",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0042168//heme metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0019290//siderophore biosynthetic process;GO:0030855//epithelial cell differentiation;GO:0055072//iron ion homeostasis,"GO:0051287//NAD binding;GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0003858//3-hydroxybutyrate dehydrogenase activity",K00019//Metabolic pathways;Butanoate metabolism;Synthesis and degradation of ketone bodies
56899,38,0,0,92,84,7,0,1,79,0,16,0,ANKS1B;ankyrin repeat and sterile alpha motif domain containing 1B,GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0015030//Cajal body;GO:0014069//postsynaptic density,-,GO:0046875//ephrin receptor binding,K12474//Endocytosis
5690,106,0,0,11,44,0,64,0,40,0,4,0,"PSMB2;proteasome (prosome, macropain) subunit, beta type, 2",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0014070//response to organic cyclic compound;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010243//response to organonitrogen compound",GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity,K02734//Proteasome
56900,0,3,0,60,132,0,0,0,26,0,22,0,TMEM167B;transmembrane protein 167B,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,-,-,-
56901,0,0,0,0,0,0,0,49,16,0,5,230,"NDUFA4L2;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2",-,-,-,K03948//Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways
56902,0,0,0,0,21,0,0,0,11,0,0,0,PNO1;partner of NOB1 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,-
56903,104,0,0,0,0,10,8,0,38,0,0,0,PAPOLB;poly(A) polymerase beta (testis specific),GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006369//termination of RNA polymerase II transcription;GO:0006378//mRNA polyadenylation;GO:0000398//mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0046872//metal ion binding,K14376//mRNA surveillance pathway
56904,0,3,0,0,0,3,33,0,21,85,7,0,SH3GLB2;SH3-domain GRB2-like endophilin B2,GO:0005737//cytoplasm,-,GO:0005515//protein binding,K11248//Endocytosis
56905,0,21,0,0,0,13,16,0,10,0,0,4,C15orf39;chromosome 15 open reading frame 39,GO:0005737//cytoplasm,-,-,-
56906,0,0,0,0,0,0,0,0,26,0,0,0,THAP10;THAP domain containing 10,-,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
56907,0,53,0,14,43,0,0,53,41,40,2,0,SPIRE1;spire-type actin nucleation factor 1,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0032154//cleavage furrow;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005938//cell cortex,GO:0015031//protein transport;GO:0036089//cleavage furrow formation;GO:0030036//actin cytoskeleton organization;GO:0051295//establishment of meiotic spindle localization;GO:0040038//polar body extrusion after meiotic divisions;GO:0048193//Golgi vesicle transport;GO:0070649//formin-nucleated actin cable assembly;GO:0046907//intracellular transport;GO:0016192//vesicle-mediated transport,GO:0003779//actin binding,K02098//Dorso-ventral axis formation
5691,0,0,0,25,49,0,0,0,12,0,0,0,"PSMB3;proteasome (prosome, macropain) subunit, beta type, 3",GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005634//nucleus,"GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02735//Proteasome
56910,0,60,45,57,213,13,0,0,28,0,0,0,STARD7;StAR-related lipid transfer (START) domain containing 7,GO:0005739//mitochondrion,-,GO:0008289//lipid binding,-
56911,0,0,0,0,1,28,0,0,0,1,0,0,MAP3K7CL;MAP3K7 C-terminal like,GO:0005829//cytosol;GO:0005634//nucleus,-,GO:0005515//protein binding,K04427//Toxoplasmosis;Leishmaniasis;T cell receptor signaling pathway;Osteoclast differentiation;MAPK signaling pathway;Herpes simplex infection;Wnt signaling pathway;Adherens junction;Measles;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway
56912,1,0,0,28,40,45,0,0,9,0,0,0,IFT46;intraflagellar transport 46,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031512//motile primary cilium;GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0036064//ciliary basal body,GO:0042073//intraciliary transport;GO:0050821//protein stabilization;GO:0042384//cilium assembly;GO:0007224//smoothened signaling pathway,GO:0008022//protein C-terminus binding,-
56915,0,0,0,0,0,0,0,32,10,0,11,56,EXOSC5;exosome component 5,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0035327//transcriptionally active chromatin;GO:0000178//exosome (RNase complex);GO:0005737//cytoplasm,"GO:0045006//DNA deamination;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0006364//rRNA processing;GO:0051607//defense response to virus;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0000175//3'-5'-exoribonuclease activity;GO:0005515//protein binding;GO:0004532//exoribonuclease activity;GO:0003723//RNA binding,K12590//RNA degradation
56916,0,0,0,16,103,42,0,0,43,0,0,0,"SMARCAD1;SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1",GO:0043596//nuclear replication fork;GO:0035861//site of double-strand break;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0000792//heterochromatin,"GO:0070933//histone H4 deacetylation;GO:0006338//chromatin remodeling;GO:0000018//regulation of DNA recombination;GO:0051304//chromosome separation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000729//DNA double-strand break processing;GO:0051260//protein homooligomerization;GO:0070932//histone H3 deacetylation;GO:0009117//nucleotide metabolic process;GO:0043044//ATP-dependent chromatin remodeling;GO:0016568//chromatin modification",GO:0003676//nucleic acid binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004386//helicase activity,-
56918,0,0,0,0,0,15,0,0,5,0,0,0,C2orf83;chromosome 2 open reading frame 83,GO:0016020//membrane,GO:0006810//transport,-,K14610//Vitamin digestion and absorption;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
56919,12,0,1,0,0,0,0,53,13,25,0,0,DHX33;DEAH (Asp-Glu-Ala-His) box polypeptide 33,GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0006200//ATP catabolic process,GO:0033613//activating transcription factor binding;GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity;GO:0000182//rDNA binding;GO:0005524//ATP binding,K12813//Spliceosome;K12818//Spliceosome
5692,0,49,1,27,54,0,0,0,0,0,1,0,"PSMB4;proteasome (prosome, macropain) subunit, beta type, 4",GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex,"GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0006915//apoptotic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression",GO:0001530//lipopolysaccharide binding;GO:0004298//threonine-type endopeptidase activity,K02736//Proteasome
56920,0,0,1,0,0,0,0,0,44,0,22,0,"SEMA3G;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0007275//multicellular organismal development,GO:0004872//receptor activity,K06840//Axon guidance
56922,0,0,0,21,33,67,51,0,38,0,0,0,MCCC1;methylcrotonoyl-CoA carboxylase 1 (alpha),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0006768//biotin metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0006766//vitamin metabolic process;GO:0006552//leucine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0005524//ATP binding;GO:0004485//methylcrotonoyl-CoA carboxylase activity;GO:0004075//biotin carboxylase activity;GO:0009374//biotin binding;GO:0005515//protein binding;GO:0046872//metal ion binding,"K01968//Valine, leucine and isoleucine degradation;Metabolic pathways"
56923,0,0,0,0,0,0,0,0,13,0,0,0,NMUR2;neuromedin U receptor 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0048265//response to pain;GO:0007631//feeding behavior;GO:0050482//arachidonic acid secretion;GO:0002023//reduction of food intake in response to dietary excess;GO:0048016//inositol phosphate-mediated signaling;GO:1902476//chloride transmembrane transport;GO:0019722//calcium-mediated signaling;GO:0007625//grooming behavior;GO:0006816//calcium ion transport;GO:0043006//activation of phospholipase A2 activity by calcium-mediated signaling;GO:0007417//central nervous system development;GO:0007218//neuropeptide signaling pathway;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0006940//regulation of smooth muscle contraction;GO:0006821//chloride transport;GO:0007267//cell-cell signaling;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0005229//intracellular calcium activated chloride channel activity;GO:0001607//neuromedin U receptor activity;GO:0042924//neuromedin U binding;GO:0005525//GTP binding;GO:0004930//G-protein coupled receptor activity,K05053//Neuroactive ligand-receptor interaction
56924,0,0,0,0,1,5,19,98,39,3,13,0,PAK6;p21 protein (Cdc42/Rac)-activated kinase 6,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K05735//Regulation of actin cytoskeleton;Axon guidance;T cell receptor signaling pathway;Focal adhesion;Renal cell carcinoma;ErbB signaling pathway
56925,0,0,0,13,1,8,0,0,0,0,0,0,LXN;latexin,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0010951//negative regulation of endopeptidase activity;GO:0006954//inflammatory response,GO:0008191//metalloendopeptidase inhibitor activity;GO:0008201//heparin binding,-
56926,0,0,0,0,0,0,0,0,28,0,0,0,NCLN;nicalin,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0009966//regulation of signal transduction,GO:0005515//protein binding,-
56927,0,0,0,0,0,0,0,48,10,0,7,0,GPR108;G protein-coupled receptor 108,GO:0016021//integral component of membrane,-,-,-
56928,40,34,0,0,0,0,18,62,15,0,0,0,SPPL2B;signal peptide peptidase like 2B,GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0005765//lysosomal membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane,GO:0050776//regulation of immune response;GO:0006509//membrane protein ectodomain proteolysis;GO:0031293//membrane protein intracellular domain proteolysis,"GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving",-
56929,0,0,1,39,55,19,0,0,18,0,0,0,FEM1C;fem-1 homolog c (C. elegans),GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,-,-
5693,0,1,0,19,48,0,0,0,1,0,0,0,"PSMB5;proteasome (prosome, macropain) subunit, beta type, 5",GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005839//proteasome core complex;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,"GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006915//apoptotic process;GO:0006979//response to oxidative stress;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I",GO:0004298//threonine-type endopeptidase activity;GO:0005515//protein binding,K02737//Proteasome
56931,0,0,0,0,0,0,20,0,11,0,0,0,DUS3L;dihydrouridine synthase 3-like (S. cerevisiae),-,GO:0055114//oxidation-reduction process;GO:0002943//tRNA dihydrouridine synthesis,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0017150//tRNA dihydrouridine synthase activity;GO:0050660//flavin adenine dinucleotide binding,-
56934,0,0,0,0,0,15,0,0,21,0,0,0,CA10;carbonic anhydrase X,-,GO:0007420//brain development,-,K01672//Collecting duct acid secretion;Nitrogen metabolism;Pancreatic secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
56935,0,24,0,5,97,0,0,0,0,0,0,242,SMCO4;single-pass membrane protein with coiled-coil domains 4,GO:0016021//integral component of membrane,-,-,-
56936,0,0,0,0,0,0,0,0,40,0,0,0,CCDC177;coiled-coil domain containing 177,-,-,-,-
56937,1,558,919,1176,1614,5,109,1195,422,292,1916,1,"PMEPA1;prostate transmembrane protein, androgen induced 1",GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0031901//early endosome membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0030521//androgen receptor signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0007179//transforming growth factor beta receptor signaling pathway,GO:0005515//protein binding;GO:0070412//R-SMAD binding;GO:0050699//WW domain binding,-
56938,0,0,0,0,0,32,4,0,125,0,4,0,ARNTL2;aryl hydrocarbon receptor nuclear translocator-like 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0009649//entrainment of circadian clock;GO:0042753//positive regulation of circadian rhythm;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0006366//transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004871//signal transducer activity;GO:0070888//E-box binding;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0046983//protein dimerization activity,-
5694,0,0,0,0,0,17,0,0,21,0,0,190,"PSMB6;proteasome (prosome, macropain) subunit, beta type, 6",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005839//proteasome core complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0004298//threonine-type endopeptidase activity;GO:0004175//endopeptidase activity,K02738//Proteasome
56940,99,0,0,0,29,16,0,0,60,0,0,452,DUSP22;dual specificity phosphatase 22,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006915//apoptotic process;GO:0000188//inactivation of MAPK activity;GO:0008283//cell proliferation;GO:0046330//positive regulation of JNK cascade;GO:0007275//multicellular organismal development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0007179//transforming growth factor beta receptor signaling pathway,GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity,K04459//MAPK signaling pathway;Serotonergic synapse;Transcriptional misregulation in cancer
56941,0,75,0,0,55,1,0,0,19,0,0,0,"HMCES;5-hydroxymethylcytosine (hmC) binding, ES cell-specific",-,GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0003677//DNA binding,K05696//Adherens junction;Insulin signaling pathway
56942,0,1,0,0,0,0,0,0,0,0,0,0,CMC2;C-x(9)-C motif containing 2,GO:0005739//mitochondrion,-,-,-
56943,0,0,0,0,7,0,0,0,0,0,0,0,ENY2;enhancer of yellow 2 homolog (Drosophila),GO:0000124//SAGA complex;GO:0070390//transcription export complex 2;GO:0005643//nuclear pore;GO:0071819//DUBm complex,"GO:0006325//chromatin organization;GO:0015031//protein transport;GO:0016578//histone deubiquitination;GO:0006406//mRNA export from nucleus;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003713//transcription coactivator activity,-
56944,46,0,0,0,0,25,0,36,11,155,9,1,OLFML3;olfactomedin-like 3,GO:0031982//vesicle;GO:0005576//extracellular region,GO:0007275//multicellular organismal development,-,-
56945,0,1,0,46,49,0,0,0,12,179,52,0,MRPS22;mitochondrial ribosomal protein S22,GO:0005739//mitochondrion;GO:0005761//mitochondrial ribosome;GO:0005763//mitochondrial small ribosomal subunit,-,GO:0003735//structural constituent of ribosome,-
56947,106,1,1,21,33,0,0,0,62,0,13,0,MFF;mitochondrial fission factor,GO:0005777//peroxisome;GO:0032592//integral component of mitochondrial membrane;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane,GO:0006626//protein targeting to mitochondrion;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:1900063//regulation of peroxisome organization;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008053//mitochondrial fusion;GO:0070584//mitochondrion morphogenesis;GO:0001836//release of cytochrome c from mitochondria;GO:0000266//mitochondrial fission;GO:0010821//regulation of mitochondrion organization;GO:0090314//positive regulation of protein targeting to membrane;GO:0051260//protein homooligomerization;GO:0090141//positive regulation of mitochondrial fission;GO:0016559//peroxisome fission,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
56948,0,359,128,401,657,0,44,408,103,0,858,149,"SDR39U1;short chain dehydrogenase/reductase family 39U, member 1",GO:0005634//nucleus,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
56949,32,0,2,22,0,0,20,83,0,0,12,1,XAB2;XPA binding protein 2,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane,"GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0006281//DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0001824//blastocyst development",GO:0005515//protein binding,K12867//Spliceosome
5695,0,290,753,1195,1511,9,29,0,109,1,1582,0,"PSMB7;proteasome (prosome, macropain) subunit, beta type, 7",GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005839//proteasome core complex;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process",GO:0005515//protein binding;GO:0004298//threonine-type endopeptidase activity,K02739//Proteasome
56950,0,0,0,17,39,0,0,0,44,0,0,0,SMYD2;SET and MYND domain containing 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,"GO:0006351//transcription, DNA-templated;GO:0018026//peptidyl-lysine monomethylation;GO:0018027//peptidyl-lysine dimethylation;GO:0043516//regulation of DNA damage response, signal transduction by p53 class mediator;GO:0010452//histone H3-K36 methylation;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0016279//protein-lysine N-methyltransferase activity;GO:0000993//RNA polymerase II core binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0002039//p53 binding,-
56951,0,0,0,0,0,0,0,0,14,0,0,0,C5orf15;chromosome 5 open reading frame 15,GO:0016021//integral component of membrane,-,-,-
56952,0,0,0,0,0,0,0,0,5,0,0,0,PRTFDC1;phosphoribosyl transferase domain containing 1,GO:0005829//cytosol,GO:0032263//GMP salvage;GO:0046038//GMP catabolic process;GO:0006178//guanine salvage;GO:0032264//IMP salvage;GO:0006166//purine ribonucleoside salvage;GO:0006168//adenine salvage;GO:0046100//hypoxanthine metabolic process,GO:0042803//protein homodimerization activity;GO:0000166//nucleotide binding;GO:0004422//hypoxanthine phosphoribosyltransferase activity;GO:0000287//magnesium ion binding,K00760//Metabolic pathways;Biosynthesis of secondary metabolites;Selenocompound metabolism;Drug metabolism - other enzymes;Purine metabolism
56953,0,0,0,0,0,14,0,0,1,0,0,0,"NT5M;5',3'-nucleotidase, mitochondrial",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006206//pyrimidine nucleobase metabolic process;GO:0016311//dephosphorylation;GO:0046135//pyrimidine nucleoside catabolic process;GO:0009223//pyrimidine deoxyribonucleotide catabolic process;GO:0044281//small molecule metabolic process;GO:0046079//dUMP catabolic process;GO:0006260//DNA replication,GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0008253//5'-nucleotidase activity,K01081//Nicotinate and nicotinamide metabolism;Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
56954,0,0,0,0,52,15,0,0,37,105,0,0,"NIT2;nitrilase family, member 2",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0006107//oxaloacetate metabolic process;GO:0006541//glutamine metabolic process;GO:0006528//asparagine metabolic process,GO:0050152//omega-amidase activity,"K13566//Alanine, aspartate and glutamate metabolism"
56955,0,0,0,0,0,16,0,0,38,0,0,0,MEPE;matrix extracellular phosphoglycoprotein,GO:0005578//proteinaceous extracellular matrix,GO:0031214//biomineral tissue development;GO:0046850//regulation of bone remodeling;GO:0001501//skeletal system development;GO:0030502//negative regulation of bone mineralization,GO:0005201//extracellular matrix structural constituent;GO:0005515//protein binding,-
56956,0,0,0,0,0,1,8,0,0,0,0,0,LHX9;LIM homeobox 9,GO:0005634//nucleus,"GO:0035262//gonad morphogenesis;GO:0008584//male gonad development;GO:0008045//motor neuron axon guidance;GO:0045892//negative regulation of transcription, DNA-templated;GO:0008585//female gonad development;GO:0008283//cell proliferation",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding;GO:0003714//transcription corepressor activity,-
56957,0,0,0,5,96,9,0,8,67,0,1,0,OTUD7B;OTU deubiquitinase 7B,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1900181//negative regulation of protein localization to nucleus;GO:0002385//mucosal immune response;GO:0035871//protein K11-linked deubiquitination;GO:0006508//proteolysis;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032717//negative regulation of interleukin-8 production,GO:0008234//cysteine-type peptidase activity;GO:0070530//K63-linked polyubiquitin binding;GO:0003677//DNA binding;GO:1990380//Lys48-specific deubiquitinase activity;GO:0004221//ubiquitin thiolesterase activity;GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0008270//zinc ion binding,-
56961,33,0,0,0,0,0,0,0,17,131,0,0,SHD;Src homology 2 domain containing transforming protein D,-,-,GO:0005515//protein binding,K08887//ErbB signaling pathway;Viral myocarditis;K07365//Pathogenic Escherichia coli infection;ErbB signaling pathway;T cell receptor signaling pathway;Axon guidance
56963,82,0,0,0,0,32,4,0,11,0,0,0,RGMA;repulsive guidance molecule family member a,GO:0031225//anchored component of membrane;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030510//regulation of BMP signaling pathway;GO:0030509//BMP signaling pathway;GO:0007411//axon guidance;GO:0001843//neural tube closure,GO:0015026//coreceptor activity,-
56964,89,0,70,229,139,26,57,0,73,102,119,1,WDR93;WD repeat domain 93,-,GO:0022900//electron transport chain,"GO:0016651//oxidoreductase activity, acting on NAD(P)H",K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
56965,0,0,2,20,0,4,0,0,27,0,6,0,"PARP6;poly (ADP-ribose) polymerase family, member 6",-,GO:0008152//metabolic process,GO:0003950//NAD+ ADP-ribosyltransferase activity,-
56967,0,18,0,0,49,22,42,33,38,0,0,0,C14orf132;chromosome 14 open reading frame 132,GO:0016021//integral component of membrane,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
56969,2,0,0,0,0,0,6,0,9,0,0,0,RPL23AP32;ribosomal protein L23a pseudogene 32,-,-,-,K02893//Ribosome
5697,0,0,0,0,0,0,29,2,47,0,0,0,PYY;peptide YY,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006928//cellular component movement;GO:0007010//cytoskeleton organization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042755//eating behavior;GO:0008283//cell proliferation;GO:0007631//feeding behavior;GO:0007586//digestion;GO:0007267//cell-cell signaling,GO:0005184//neuropeptide hormone activity;GO:0005179//hormone activity;GO:0005515//protein binding,-
56970,0,0,25,13,9,6,43,71,39,0,0,0,ATXN7L3;ataxin 7-like 3,GO:0000124//SAGA complex;GO:0071819//DUBm complex,"GO:0006325//chromatin organization;GO:0016578//histone deubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003713//transcription coactivator activity,-
56971,161,0,0,0,0,42,0,0,19,0,0,0,CEACAM19;carcinoembryonic antigen-related cell adhesion molecule 19,GO:0016021//integral component of membrane,-,-,-
56975,79,0,0,0,0,0,0,1,13,0,0,0,"FAM20C;family with sequence similarity 20, member C",GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0051174//regulation of phosphorus metabolic process;GO:0070166//enamel mineralization;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0045669//positive regulation of osteoblast differentiation;GO:0071895//odontoblast differentiation;GO:0036179//osteoclast maturation;GO:0001501//skeletal system development;GO:0097187//dentinogenesis;GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005509//calcium ion binding,-
56977,0,0,0,0,0,24,0,0,37,33,0,0,STOX2;storkhead box 2,-,GO:0001893//maternal placenta development;GO:0009790//embryo development,-,-
56978,59,31,62,30,77,11,0,0,16,0,70,0,PRDM8;PR domain containing 8,GO:0005634//nucleus,"GO:0051567//histone H3-K9 methylation;GO:0021540//corpus callosum morphogenesis;GO:0021957//corticospinal tract morphogenesis;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity,K12463//Neurotrophin signaling pathway
56979,4,0,0,0,0,14,0,0,17,97,8,0,PRDM9;PR domain containing 9,GO:0005654//nucleoplasm;GO:0005694//chromosome,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0007283//spermatogenesis;GO:0006311//meiotic gene conversion;GO:0060903//positive regulation of meiosis I;GO:0010845//positive regulation of reciprocal meiotic recombination",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0010844//recombination hotspot binding,-
56980,0,0,0,6,13,15,48,44,41,0,0,313,PRDM10;PR domain containing 10,GO:0005634//nucleus,"GO:0032259//methylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity,-
56981,96,0,0,0,0,23,1,0,66,161,15,0,PRDM11;PR domain containing 11,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K12463//Neurotrophin signaling pathway
56983,0,0,0,0,5,59,16,0,23,18,1,0,POGLUT1;protein O-glucosyltransferase 1,GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen,GO:0006493//protein O-linked glycosylation;GO:0008593//regulation of Notch signaling pathway;GO:0007219//Notch signaling pathway;GO:0072358//cardiovascular system development,GO:0046527//glucosyltransferase activity;GO:0030158//protein xylosyltransferase activity;GO:0035251//UDP-glucosyltransferase activity,K13667//Other types of O-glycan biosynthesis
56984,0,0,0,0,68,0,0,25,22,0,0,0,"PSMG2;proteasome (prosome, macropain) assembly chaperone 2",GO:0005634//nucleus,GO:0007094//mitotic spindle assembly checkpoint;GO:0043248//proteasome assembly;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding,-
56985,0,45,55,62,86,0,0,0,42,0,120,0,"ADPRM;ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent",-,GO:0008152//metabolic process,GO:0047734//CDP-glycerol diphosphatase activity;GO:0046872//metal ion binding;GO:0047631//ADP-ribose diphosphatase activity,K01517//Glycerophospholipid metabolism;Purine metabolism
56986,0,2,0,1,14,0,0,0,10,0,0,0,DTWD1;DTW domain containing 1,-,-,-,-
56987,0,29,5,70,160,0,32,68,37,0,0,0,BBX;bobby sox homolog (Drosophila),GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0060348//bone development;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,K04495//Wnt signaling pathway
5699,0,36,0,16,0,0,0,0,6,0,0,0,"PSMB10;proteasome (prosome, macropain) subunit, beta type, 10",GO:0005839//proteasome core complex;GO:1990111//spermatoproteasome complex;GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0000502//proteasome complex,"GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006959//humoral immune response;GO:0000902//cell morphogenesis;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042098//T cell proliferation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process",GO:0004298//threonine-type endopeptidase activity,K02733//Proteasome
56990,0,0,0,109,233,7,10,0,11,0,0,0,CDC42SE2;CDC42 small effector 2,GO:0001891//phagocytic cup;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0042995//cell projection;GO:0005737//cytoplasm,GO:0008360//regulation of cell shape;GO:0009966//regulation of signal transduction;GO:0006909//phagocytosis,GO:0005515//protein binding;GO:0005198//structural molecule activity,-
56992,80,0,0,0,0,0,0,0,81,0,0,319,KIF15;kinesin family member 15,GO:0005813//centrosome;GO:0005819//spindle;GO:0005874//microtubule;GO:0016020//membrane;GO:0005829//cytosol;GO:0005873//plus-end kinesin complex;GO:0005871//kinesin complex,GO:0007067//mitotic nuclear division;GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007018//microtubule-based movement;GO:0008283//cell proliferation,GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0003677//DNA binding;GO:0005524//ATP binding,-
56993,2,1,0,3,36,0,0,0,1,0,0,0,TOMM22;translocase of outer mitochondrial membrane 22 homolog (yeast),GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0045040//protein import into mitochondrial outer membrane;GO:0044267//cellular protein metabolic process;GO:0006626//protein targeting to mitochondrion,GO:0008320//protein transmembrane transporter activity;GO:0005515//protein binding,-
56994,0,0,0,14,5,12,0,0,0,0,0,0,CHPT1;choline phosphotransferase 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0006663//platelet activating factor biosynthetic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0006657//CDP-choline pathway;GO:0001558//regulation of cell growth;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006629//lipid metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0004142//diacylglycerol cholinephosphotransferase activity;GO:0019992//diacylglycerol binding,K00994//Metabolic pathways;Glycerophospholipid metabolism;Ether lipid metabolism
56995,173,217,29,115,356,7,39,2,166,0,16,1,TULP4;tubby like protein 4,GO:0005737//cytoplasm,"GO:0016567//protein ubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction;GO:0007584//response to nutrient",GO:0003700//sequence-specific DNA binding transcription factor activity,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
56996,0,0,0,0,0,19,26,0,49,0,0,0,"SLC12A9;solute carrier family 12, member 9",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:1902476//chloride transmembrane transport;GO:0006821//chloride transport,GO:0015377//cation:chloride symporter activity,-
56997,0,0,0,2,2,0,42,0,35,0,0,0,ADCK3;aarF domain containing kinase 3,GO:0005739//mitochondrion,GO:0008219//cell death;GO:0006468//protein phosphorylation;GO:0006744//ubiquinone biosynthetic process,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
56998,0,81,4,3,55,0,64,0,17,0,0,0,"CTNNBIP1;catenin, beta interacting protein 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex,GO:0045657//positive regulation of monocyte differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0043392//negative regulation of DNA binding;GO:0009952//anterior/posterior pattern specification;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060633//negative regulation of transcription initiation from RNA polymerase II promoter;GO:0045669//positive regulation of osteoblast differentiation;GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032091//negative regulation of protein binding,GO:0005515//protein binding;GO:0008013//beta-catenin binding;GO:0070016//armadillo repeat domain binding,K04493//Wnt signaling pathway
56999,78,0,0,0,0,76,16,0,44,209,0,0,"ADAMTS9;ADAM metallopeptidase with thrombospondin type 1 motif, 9",GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,GO:0007275//multicellular organismal development;GO:0006508//proteolysis;GO:0015031//protein transport;GO:0045636//positive regulation of melanocyte differentiation;GO:0006516//glycoprotein catabolic process;GO:0016192//vesicle-mediated transport,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity,-
570,3,0,0,0,0,22,22,0,23,0,0,0,BAAT;bile acid CoA:amino acid N-acyltransferase,GO:0005829//cytosol;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome,GO:0001889//liver development;GO:0015721//bile acid and bile salt transport;GO:0044281//small molecule metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0031100//organ regeneration;GO:0002152//bile acid conjugation;GO:0019530//taurine metabolic process;GO:0006544//glycine metabolic process;GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0006631//fatty acid metabolic process,GO:0016290//palmitoyl-CoA hydrolase activity;GO:0005102//receptor binding;GO:0052689//carboxylic ester hydrolase activity;GO:0016410//N-acyltransferase activity;GO:0052815//medium-chain acyl-CoA hydrolase activity;GO:0052817//very long chain acyl-CoA hydrolase activity;GO:0047963//glycine N-choloyltransferase activity,K00659//Primary bile acid biosynthesis;Metabolic pathways;Biosynthesis of unsaturated fatty acids;Bile secretion;Taurine and hypotaurine metabolism;Peroxisome
5700,0,37,2,68,218,0,0,0,13,0,6,0,"PSMC1;proteasome (prosome, macropain) 26S subunit, ATPase, 1",GO:0022624//proteasome accessory complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0044281//small molecule metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0006200//ATP catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process",GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0016887//ATPase activity,K03062//Proteasome;Epstein-Barr virus infection
57000,0,0,0,0,27,0,1,84,20,1,98,0,GSN-AS1;GSN antisense RNA 1,-,-,-,K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
57001,0,0,0,20,0,0,0,0,0,0,0,0,ACN9;ACN9 homolog (S. cerevisiae),GO:0005758//mitochondrial intermembrane space,GO:0006111//regulation of gluconeogenesis,-,-
57002,0,0,0,0,22,26,20,0,29,0,0,0,YAE1D1;Yae1 domain containing 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
57003,0,8,0,21,39,5,37,0,25,0,8,128,CCDC47;coiled-coil domain containing 47,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0001649//osteoblast differentiation;GO:0055074//calcium ion homeostasis;GO:0009791//post-embryonic development;GO:0006983//ER overload response,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
57007,0,0,0,0,0,0,20,1,0,0,10,0,ACKR3;atypical chemokine receptor 3,GO:0005905//coated pit;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0048471//perinuclear region of cytoplasm;GO:0055037//recycling endosome,GO:0001525//angiogenesis;GO:0001570//vasculogenesis;GO:0031623//receptor internalization;GO:0016032//viral process;GO:0007155//cell adhesion;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006935//chemotaxis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070098//chemokine-mediated signaling pathway,GO:0015026//coreceptor activity;GO:0005044//scavenger receptor activity;GO:0019958//C-X-C chemokine binding;GO:0016494//C-X-C chemokine receptor activity;GO:0005515//protein binding,K04304//Cytokine-cytokine receptor interaction
5701,40,1,1,98,107,12,0,0,24,0,0,0,"PSMC2;proteasome (prosome, macropain) 26S subunit, ATPase, 2",GO:0022624//proteasome accessory complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process;GO:0006200//ATP catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0001649//osteoblast differentiation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process",GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0005515//protein binding,K03061//Epstein-Barr virus infection;Proteasome
57016,0,0,0,0,0,10,55,0,4,0,6,0,"AKR1B10;aldo-keto reductase family 1, member B10 (aldose reductase)",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005764//lysosome,"GO:0044598//doxorubicin metabolic process;GO:0001523//retinoid metabolic process;GO:0007586//digestion;GO:0007603//phototransduction, visible light;GO:0006081//cellular aldehyde metabolic process;GO:0008202//steroid metabolic process;GO:0044597//daunorubicin metabolic process;GO:0055114//oxidation-reduction process;GO:0016488//farnesol catabolic process",GO:0004033//aldo-keto reductase (NADP) activity;GO:0045550//geranylgeranyl reductase activity;GO:0047718//indanol dehydrogenase activity;GO:0001758//retinal dehydrogenase activity;GO:0005515//protein binding,K00011//Galactose metabolism;Pyruvate metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Glycerolipid metabolism;Fructose and mannose metabolism
57017,0,0,0,0,25,0,0,0,13,12,0,0,COQ9;coenzyme Q9,GO:0005739//mitochondrion,"GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0006744//ubiquinone biosynthetic process",-,K03011//Metabolic pathways;Huntington's disease;Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism
57018,0,43,71,37,60,0,17,203,18,0,201,0,CCNL1;cyclin L1,GO:0005634//nucleus;GO:0016607//nuclear speck,"GO:0006355//regulation of transcription, DNA-templated;GO:0006396//RNA processing;GO:0006351//transcription, DNA-templated;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity",GO:0019901//protein kinase binding,K15188//Transcriptional misregulation in cancer
57019,0,45,0,24,1,0,0,71,2,0,49,0,CIAPIN1;cytokine induced apoptosis inhibitor 1,GO:0005730//nucleolus;GO:0005758//mitochondrial intermembrane space;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0030097//hemopoiesis;GO:0044281//small molecule metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0016226//iron-sulfur cluster assembly,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0009055//electron carrier activity;GO:0046872//metal ion binding;GO:0005515//protein binding",-
5702,2,0,0,0,11,0,15,0,14,0,8,0,"PSMC3;proteasome (prosome, macropain) 26S subunit, ATPase, 3",GO:0022624//proteasome accessory complex;GO:0016020//membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:2001141//regulation of RNA biosynthetic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0003713//transcription coactivator activity;GO:0005524//ATP binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0016887//ATPase activity,K03065//Epstein-Barr virus infection;Proteasome
57020,0,0,0,9,0,0,0,0,0,0,0,0,C16orf62;chromosome 16 open reading frame 62,GO:0016021//integral component of membrane,-,-,-
57026,0,1,0,0,0,15,0,0,0,0,9,0,"PDXP;pyridoxal (pyridoxine, vitamin B6) phosphatase",GO:0070938//contractile ring;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0031258//lamellipodium membrane;GO:0030496//midbody;GO:0030027//lamellipodium;GO:0032154//cleavage furrow;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0032361//pyridoxal phosphate catabolic process;GO:0006470//protein dephosphorylation;GO:0031247//actin rod assembly;GO:0071318//cellular response to ATP;GO:0032465//regulation of cytokinesis;GO:0030836//positive regulation of actin filament depolymerization;GO:0007088//regulation of mitosis,GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity;GO:0031072//heat shock protein binding;GO:0004647//phosphoserine phosphatase activity;GO:0000287//magnesium ion binding;GO:0033883//pyridoxal phosphatase activity,K07758//Metabolic pathways;Vitamin B6 metabolism
57030,145,1,0,0,0,6,9,0,15,154,23,0,"SLC17A7;solute carrier family 17 (vesicular glutamate transporter), member 7",GO:0005886//plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0044300//cerebellar mossy fiber;GO:0060076//excitatory synapse;GO:0048786//presynaptic active zone,"GO:0042137//sequestering of neurotransmitter;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0006817//phosphate ion transport;GO:0006811//ion transport;GO:0014047//glutamate secretion;GO:0035249//synaptic transmission, glutamatergic;GO:0051938//L-glutamate import;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0007616//long-term memory;GO:0035435//phosphate ion transmembrane transport;GO:0044341//sodium-dependent phosphate transport",GO:0005313//L-glutamate transmembrane transporter activity;GO:0015319//sodium:inorganic phosphate symporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity,K12302//Glutamatergic synapse;Nicotine addiction;Synaptic vesicle cycle;Retrograde endocannabinoid signaling
57037,0,0,0,4,1,17,0,53,11,0,8,0,ANKMY2;ankyrin repeat and MYND domain containing 2,GO:0005929//cilium,-,GO:0046872//metal ion binding,K11420//Lysine degradation
57038,0,23,49,0,74,14,0,0,13,0,0,0,"RARS2;arginyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0006420//arginyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0044822//poly(A) RNA binding;GO:0004814//arginine-tRNA ligase activity;GO:0005524//ATP binding,K01887//Aminoacyl-tRNA biosynthesis
5704,0,3,0,12,95,0,0,0,4,0,0,0,"PSMC4;proteasome (prosome, macropain) 26S subunit, ATPase, 4",GO:0016020//membrane;GO:0016234//inclusion body;GO:0022624//proteasome accessory complex;GO:0000502//proteasome complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0031597//cytosolic proteasome complex;GO:0005634//nucleus,"GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0006508//proteolysis;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006200//ATP catabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0001824//blastocyst development;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process",GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K03063//Epstein-Barr virus infection;Proteasome
57045,1,0,0,7,18,0,15,34,33,0,0,0,TWSG1;twisted gastrulation BMP signaling modulator 1,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0043010//camera-type eye development;GO:0030514//negative regulation of BMP signaling pathway;GO:0030154//cell differentiation;GO:0001707//mesoderm formation;GO:0001503//ossification;GO:0030513//positive regulation of BMP signaling pathway;GO:0030900//forebrain development;GO:0030509//BMP signaling pathway;GO:0007435//salivary gland morphogenesis;GO:0045668//negative regulation of osteoblast differentiation;GO:0030097//hemopoiesis,-,K01810//Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Pentose phosphate pathway
57047,80,0,1,0,0,3,0,0,27,0,0,0,PLSCR2;phospholipid scramblase 2,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0017121//phospholipid scrambling,GO:0017128//phospholipid scramblase activity;GO:0005509//calcium ion binding,K08267//mTOR signaling pathway
57048,0,0,0,0,0,9,0,0,0,0,0,0,PLSCR3;phospholipid scramblase 3,GO:0005886//plasma membrane;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,GO:0071222//cellular response to lipopolysaccharide;GO:0042632//cholesterol homeostasis;GO:0017121//phospholipid scrambling;GO:0042593//glucose homeostasis;GO:0006915//apoptotic process,GO:0017128//phospholipid scramblase activity;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0017124//SH3 domain binding;GO:0005515//protein binding,K08267//mTOR signaling pathway
5705,0,48,3,10,112,0,0,49,0,0,0,0,"PSMC5;proteasome (prosome, macropain) 26S subunit, ATPase, 5",GO:0016020//membrane;GO:0016234//inclusion body;GO:0031595//nuclear proteasome complex;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0031410//cytoplasmic vesicle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031597//cytosolic proteasome complex;GO:0005634//nucleus,"GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090261//positive regulation of inclusion body assembly;GO:0006915//apoptotic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043069//negative regulation of programmed cell death;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process",GO:0003712//transcription cofactor activity;GO:0005524//ATP binding;GO:0031531//thyrotropin-releasing hormone receptor binding;GO:0017025//TBP-class protein binding;GO:0008134//transcription factor binding;GO:0016887//ATPase activity;GO:0005515//protein binding,K03066//Epstein-Barr virus infection;Proteasome
57050,0,1,0,30,21,0,21,0,21,0,0,0,"UTP3;UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)",GO:0005730//nucleolus;GO:0005634//nucleus,GO:0007420//brain development;GO:0016568//chromatin modification,GO:0044822//poly(A) RNA binding,-
57053,0,0,0,0,0,0,0,0,15,0,0,0,"CHRNA10;cholinergic receptor, nicotinic, alpha 10 (neuronal)",GO:0030054//cell junction;GO:0030424//axon;GO:0043204//perikaryon;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0016020//membrane,"GO:0007271//synaptic transmission, cholinergic;GO:0070588//calcium ion transmembrane transport;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0042127//regulation of cell proliferation;GO:0042472//inner ear morphogenesis;GO:0007204//positive regulation of cytosolic calcium ion concentration",GO:0005262//calcium channel activity;GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0005102//receptor binding,K04811//Neuroactive ligand-receptor interaction
57057,0,0,0,0,0,0,0,0,2,40,0,0,TBX20;T-box 20,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001706//endoderm formation;GO:0003143//embryonic heart tube morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0048370//lateral mesoderm formation;GO:0003193//pulmonary valve formation;GO:0001947//heart looping;GO:0003272//endocardial cushion formation;GO:0003279//cardiac septum development;GO:0060413//atrial septum morphogenesis;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0003344//pericardium morphogenesis;GO:0060577//pulmonary vein morphogenesis;GO:0021524//visceral motor neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0003175//tricuspid valve development;GO:0008015//blood circulation;GO:0003148//outflow tract septum morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003207//cardiac chamber formation;GO:0003215//cardiac right ventricle morphogenesis;GO:0035922//foramen ovale closure;GO:0036306//embryonic heart tube elongation;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0006936//muscle contraction;GO:0055008//cardiac muscle tissue morphogenesis;GO:0001764//neuron migration;GO:0001569//patterning of blood vessels;GO:0003180//aortic valve morphogenesis",GO:0001085//RNA polymerase II transcription factor binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001102//RNA polymerase II activating transcription factor binding,-
5706,0,0,0,49,43,0,1,0,22,0,0,0,"PSMC6;proteasome (prosome, macropain) 26S subunit, ATPase, 6",GO:0022624//proteasome accessory complex;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex,"GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression","GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0030674//protein binding, bridging",K03064//Epstein-Barr virus infection;Proteasome
57060,112,1,1,4,12,0,0,49,0,0,11,2,PCBP4;poly(rC) binding protein 4,GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm,-,GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,-
57062,0,37,32,12,44,17,47,0,40,0,34,0,DDX24;DEAD (Asp-Glu-Ala-Asp) box helicase 24,GO:0016020//membrane;GO:0005730//nucleolus,GO:0006200//ATP catabolic process;GO:0016070//RNA metabolic process,GO:0003724//RNA helicase activity;GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
5707,76,1,0,39,144,0,0,0,22,0,0,0,"PSMD1;proteasome (prosome, macropain) 26S subunit, non-ATPase, 1",GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0044281//small molecule metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042176//regulation of protein catabolic process;GO:0006915//apoptotic process",GO:0030234//enzyme regulator activity,K03032//Proteasome;Epstein-Barr virus infection
5708,0,51,1,19,22,0,1,1,6,0,0,482,"PSMD2;proteasome (prosome, macropain) 26S subunit, non-ATPase, 2",GO:0000502//proteasome complex;GO:0005838//proteasome regulatory particle;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0016020//membrane;GO:0005829//cytosol,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042176//regulation of protein catabolic process;GO:0006915//apoptotic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0044281//small molecule metabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle",GO:0030234//enzyme regulator activity;GO:0005515//protein binding,K03028//Epstein-Barr virus infection;Proteasome
57082,0,0,0,0,25,31,1,0,60,0,0,0,CASC5;cancer susceptibility candidate 5,GO:0070062//extracellular vesicular exosome;GO:0000777//condensed chromosome kinetochore;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0001669//acrosomal vesicle;GO:0005829//cytosol;GO:0005634//nucleus,GO:0071173//spindle assembly checkpoint;GO:0010923//negative regulation of phosphatase activity;GO:0006334//nucleosome assembly;GO:0034080//CENP-A containing nucleosome assembly;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0007067//mitotic nuclear division;GO:0001675//acrosome assembly;GO:0034501//protein localization to kinetochore;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,-
57084,0,0,0,0,0,9,0,0,16,118,0,0,"SLC17A6;solute carrier family 17 (vesicular glutamate transporter), member 6",GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction,GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:0001504//neurotransmitter uptake;GO:0055085//transmembrane transport;GO:0015813//L-glutamate transport,GO:0015293//symporter activity;GO:0005313//L-glutamate transmembrane transporter activity,K12302//Nicotine addiction;Glutamatergic synapse;Synaptic vesicle cycle;Retrograde endocannabinoid signaling
57085,74,0,0,8,15,0,24,0,11,0,8,0,AGTRAP;angiotensin II receptor-associated protein,GO:0005789//endoplasmic reticulum membrane;GO:0005938//cell cortex;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005886//plasma membrane,GO:0038166//angiotensin-activated signaling pathway;GO:0008217//regulation of blood pressure;GO:0001666//response to hypoxia,GO:0004945//angiotensin type II receptor activity;GO:0005515//protein binding,-
57088,58,0,0,0,8,0,4,0,4,0,0,0,PLSCR4;phospholipid scramblase 4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0071222//cellular response to lipopolysaccharide;GO:0017121//phospholipid scrambling,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0042609//CD4 receptor binding;GO:0005509//calcium ion binding;GO:0017128//phospholipid scramblase activity;GO:0019899//enzyme binding,-
57089,154,42,63,70,91,0,41,25,79,11,627,9,ENTPD7;ectonucleoside triphosphate diphosphohydrolase 7,GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,-
5709,0,1,0,15,20,0,17,0,0,0,0,0,"PSMD3;proteasome (prosome, macropain) 26S subunit, non-ATPase, 3",GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005838//proteasome regulatory particle;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0022624//proteasome accessory complex;GO:0070062//extracellular vesicular exosome,"GO:0044281//small molecule metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042176//regulation of protein catabolic process;GO:0006915//apoptotic process",GO:0030234//enzyme regulator activity,K03033//Epstein-Barr virus infection;Proteasome
57091,0,0,0,0,0,0,1,0,117,0,0,0,CASS4;Cas scaffolding protein family member 4,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion;GO:0016020//membrane,GO:0000160//phosphorelay signal transduction system;GO:0023014//signal transduction by phosphorylation;GO:0007155//cell adhesion,GO:0000155//phosphorelay sensor kinase activity,K05726//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Focal adhesion;Leukocyte transendothelial migration
57092,53,86,0,79,193,0,36,0,0,0,0,0,PCNP;PEST proteolytic signal containing nuclear protein,GO:0005634//nucleus,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
57093,0,0,0,0,0,11,0,0,2,4,11,0,TRIM49;tripartite motif containing 49,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
57094,90,0,0,0,0,0,0,0,11,0,0,0,CPA6;carboxypeptidase A6,GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,-
57095,0,56,1,91,161,0,21,0,18,0,1,0,PITHD1;PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1,GO:0005634//nucleus,-,-,K03671//Selenocompound metabolism;Pyrimidine metabolism
57096,15,0,0,8,0,33,0,32,39,103,0,0,RPGRIP1;retinitis pigmentosa GTPase regulator interacting protein 1,GO:0005930//axoneme;GO:0031513//nonmotile primary cilium,GO:0042462//eye photoreceptor cell development;GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0060041//retina development in camera-type eye,GO:0005515//protein binding,-
57097,200,2,1,55,129,0,0,69,24,0,0,460,"PARP11;poly (ADP-ribose) polymerase family, member 11",-,GO:0008152//metabolic process,GO:0003950//NAD+ ADP-ribosyltransferase activity,-
57099,0,0,0,0,7,11,0,0,0,0,7,0,"AVEN;apoptosis, caspase activation inhibitor",GO:0005622//intracellular;GO:0012505//endomembrane system;GO:0016020//membrane,GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process,GO:0005515//protein binding,-
571,0,31,1,42,177,0,0,0,11,0,0,0,"BACH1;BTB and CNC homology 1, basic leucine zipper transcription factor 1",GO:0005634//nucleus;GO:0005829//cytosol,"GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000117//regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0020037//heme binding,-
5710,77,31,0,20,68,0,30,0,0,145,1,2,"PSMD4;proteasome (prosome, macropain) 26S subunit, non-ATPase, 4","GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0022624//proteasome accessory complex","GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042802//identical protein binding,K03029//Epstein-Barr virus infection;Proteasome
57101,15,0,0,0,0,22,0,0,27,0,0,0,"ANO2;anoctamin 2, calcium activated chloride channel",GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0034707//chloride channel complex;GO:0005634//nucleus,GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport;GO:0055085//transmembrane transport,GO:0005229//intracellular calcium activated chloride channel activity,-
57102,0,0,0,0,26,19,0,0,28,0,0,53,C12orf4;chromosome 12 open reading frame 4,-,-,-,-
57103,0,3,0,9,0,0,68,45,9,3,1,0,C12orf5;chromosome 12 open reading frame 5,GO:0005622//intracellular,GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0060576//intestinal epithelial cell development;GO:1901525//negative regulation of macromitophagy;GO:0009410//response to xenobiotic stimulus;GO:0010332//response to gamma radiation;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0016311//dephosphorylation,"GO:0004331//fructose-2,6-bisphosphate 2-phosphatase activity",K14634//Fructose and mannose metabolism
57104,1,23,0,0,0,0,0,0,57,0,15,0,PNPLA2;patatin-like phospholipase domain containing 2,GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005811//lipid particle;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0044281//small molecule metabolic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0019915//lipid storage;GO:0019433//triglyceride catabolic process;GO:0036155//acylglycerol acyl-chain remodeling;GO:0034389//lipid particle organization;GO:0010898//positive regulation of triglyceride catabolic process;GO:0010891//negative regulation of sequestering of triglyceride,GO:0004806//triglyceride lipase activity,K13534//Metabolic pathways;Glycerolipid metabolism
57105,0,0,0,0,0,0,0,0,54,0,7,0,CYSLTR2;cysteinyl leukotriene receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045766//positive regulation of angiogenesis;GO:0006955//immune response;GO:0010942//positive regulation of cell death,GO:0001631//cysteinyl leukotriene receptor activity;GO:0005515//protein binding;GO:0004974//leukotriene receptor activity,K04323//Calcium signaling pathway;Neuroactive ligand-receptor interaction
57106,87,0,0,0,0,0,0,0,5,0,0,0,"NAT14;N-acetyltransferase 14 (GCN5-related, putative)",GO:0016021//integral component of membrane;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation",GO:0003677//DNA binding;GO:0008080//N-acetyltransferase activity,-
57107,0,75,42,71,155,28,0,95,16,0,22,0,"PDSS2;prenyl (decaprenyl) diphosphate synthase, subunit 2",GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0006744//ubiquinone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0050878//regulation of body fluid levels;GO:0051290//protein heterotetramerization;GO:0008299//isoprenoid biosynthetic process,GO:0000010//trans-hexaprenyltranstransferase activity;GO:0050347//trans-octaprenyltranstransferase activity;GO:0046982//protein heterodimerization activity,K12505//Terpenoid backbone biosynthesis
57109,0,22,0,4,10,0,0,1,50,0,0,303,"REXO4;REX4, RNA exonuclease 4 homolog (S. cerevisiae)",GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0090305//nucleic acid phosphodiester bond hydrolysis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004527//exonuclease activity;GO:0044822//poly(A) RNA binding,-
5711,129,38,2,37,178,0,30,0,36,0,0,0,"PSMD5;proteasome (prosome, macropain) 26S subunit, non-ATPase, 5","GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0022624//proteasome accessory complex;GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006521//regulation of cellular amino acid metabolic process;GO:0070682//proteasome regulatory particle assembly;GO:0006457//protein folding;GO:0000209//protein polyubiquitination;GO:0044281//small molecule metabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process",GO:0005515//protein binding;GO:0044183//protein binding involved in protein folding,-
57110,156,0,0,0,0,0,3,0,0,0,0,1,HRASLS;HRAS-like suppressor,GO:0005641//nuclear envelope lumen;GO:0016021//integral component of membrane;GO:0005777//peroxisome,GO:0016042//lipid catabolic process;GO:0046485//ether lipid metabolic process;GO:0007031//peroxisome organization,GO:0004620//phospholipase activity;GO:0016740//transferase activity,K00678//Vitamin digestion and absorption;Retinol metabolism
57111,0,2,0,14,37,0,0,0,16,52,0,0,"RAB25;RAB25, member RAS oncogene family",GO:0031143//pseudopodium;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0070062//extracellular vesicular exosome;GO:0031260//pseudopodium membrane;GO:0031410//cytoplasmic vesicle,GO:0015031//protein transport;GO:0008284//positive regulation of cell proliferation;GO:0007264//small GTPase mediated signal transduction;GO:0031268//pseudopodium organization,GO:0005525//GTP binding;GO:0005515//protein binding,-
57113,0,0,0,0,0,0,0,0,15,0,0,0,"TRPC7;transient receptor potential cation channel, subfamily C, member 7",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope,GO:0007596//blood coagulation;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0030168//platelet activation;GO:0006828//manganese ion transport;GO:0007411//axon guidance,GO:0005262//calcium channel activity;GO:0005515//protein binding,-
57115,0,0,0,0,0,0,0,17,0,105,0,0,PGLYRP4;peptidoglycan recognition protein 4,GO:0016020//membrane;GO:0005622//intracellular;GO:0005576//extracellular region,GO:0002221//pattern recognition receptor signaling pathway;GO:0032827//negative regulation of natural killer cell differentiation involved in immune response;GO:0050830//defense response to Gram-positive bacterium;GO:0045087//innate immune response;GO:0044117//growth of symbiont in host;GO:0032689//negative regulation of interferon-gamma production;GO:0016045//detection of bacterium;GO:0009253//peptidoglycan catabolic process,GO:0016019//peptidoglycan receptor activity;GO:0008745//N-acetylmuramoyl-L-alanine amidase activity;GO:0008270//zinc ion binding;GO:0042834//peptidoglycan binding,-
57116,82,0,0,0,0,0,0,0,60,0,0,0,ZNF695;zinc finger protein 695,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
57117,0,19,0,0,58,0,0,0,19,0,0,0,INTS12;integrator complex subunit 12,GO:0032039//integrator complex,GO:0016180//snRNA processing,GO:0005515//protein binding;GO:0008270//zinc ion binding,-
57118,2,0,0,0,0,0,0,0,53,0,8,0,CAMK1D;calcium/calmodulin-dependent protein kinase ID,GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050773//regulation of dendrite development;GO:0006954//inflammatory response;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0010976//positive regulation of neuron projection development;GO:0050766//positive regulation of phagocytosis;GO:0060267//positive regulation of respiratory burst;GO:0032793//positive regulation of CREB transcription factor activity;GO:0006468//protein phosphorylation,GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,-
57119,0,0,0,0,0,0,44,0,0,0,0,0,EPPIN;epididymal peptidase inhibitor,GO:0009986//cell surface;GO:0005576//extracellular region,GO:0042742//defense response to bacterium;GO:0010951//negative regulation of endopeptidase activity;GO:0010466//negative regulation of peptidase activity,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades;K04520//Alzheimer's disease;Serotonergic synapse;K15619//Transcriptional misregulation in cancer
57120,80,66,0,32,49,41,0,0,11,0,0,255,GOPC;golgi-associated PDZ and coiled-coil motif containing,GO:0043234//protein complex;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0030140//trans-Golgi network transport vesicle;GO:0030425//dendrite;GO:0005886//plasma membrane,GO:0015031//protein transport;GO:0006893//Golgi to plasma membrane transport;GO:0007289//spermatid nucleus differentiation;GO:0050790//regulation of catalytic activity;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0045176//apical protein localization;GO:0051260//protein homooligomerization;GO:0043004//cytoplasmic sequestering of CFTR protein,GO:0005083//small GTPase regulator activity;GO:0005515//protein binding;GO:0044325//ion channel binding,K06092//Tight junction;K14548//Ribosome biogenesis in eukaryotes
57121,0,0,0,0,0,17,0,2,0,0,5,0,LPAR5;lysophosphatidic acid receptor 5,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
57122,0,15,1,3,29,9,8,0,72,0,0,14,NUP107;nucleoporin 107kDa,GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0031080//nuclear pore outer ring;GO:0000776//kinetochore;GO:0031965//nuclear membrane;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0034399//nuclear periphery;GO:0005634//nucleus,GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0015758//glucose transport;GO:0051292//nuclear pore complex assembly;GO:0044281//small molecule metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0006406//mRNA export from nucleus;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport,GO:0017056//structural constituent of nuclear pore;GO:0005515//protein binding;GO:0005487//nucleocytoplasmic transporter activity,K14301//RNA transport
57124,0,0,0,0,0,36,0,0,13,0,0,0,"CD248;CD248 molecule, endosialin",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm,GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0060033//anatomical structure regression;GO:0048535//lymph node development;GO:0008284//positive regulation of cell proliferation;GO:0016477//cell migration,GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding;GO:0050840//extracellular matrix binding,-
57125,0,19,0,6,0,25,0,101,2,147,0,0,PLXDC1;plexin domain containing 1,GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005923//tight junction;GO:0043235//receptor complex,GO:0021510//spinal cord development;GO:0001525//angiogenesis,GO:0005515//protein binding;GO:0004872//receptor activity,K11447//Transcriptional misregulation in cancer
57126,0,0,0,0,29,0,0,1,7,0,0,0,CD177;CD177 molecule,GO:0031225//anchored component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0050900//leukocyte migration;GO:0007596//blood coagulation,-,-
57127,5,0,0,0,0,23,0,51,46,0,0,0,"RHBG;Rh family, B glycoprotein (gene/pseudogene)",GO:0005886//plasma membrane;GO:0014731//spectrin-associated cytoskeleton;GO:0046658//anchored component of plasma membrane;GO:0016323//basolateral plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0072488//ammonium transmembrane transport;GO:0070634//transepithelial ammonium transport,GO:0008519//ammonium transmembrane transporter activity;GO:0030506//ankyrin binding,-
57128,0,0,0,13,1,8,0,0,0,0,0,0,LYRM4;LYR motif containing 4,GO:0005759//mitochondrial matrix;GO:0005634//nucleus,GO:0044281//small molecule metabolic process,-,K11447//Transcriptional misregulation in cancer;K01539//Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Arginine and proline metabolism;Biotin metabolism;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
57129,0,0,0,17,14,0,0,0,30,0,0,0,MRPL47;mitochondrial ribosomal protein L47,GO:0005739//mitochondrion;GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
5713,0,1,1,18,81,0,21,1,26,0,0,0,"PSMD7;proteasome (prosome, macropain) 26S subunit, non-ATPase, 7",GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0044281//small molecule metabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process",GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K03038//Epstein-Barr virus infection;Proteasome
57130,90,0,0,0,0,11,0,49,1,0,9,0,ATP13A1;ATPase type 13A1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006200//ATP catabolic process,GO:0019829//cation-transporting ATPase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,-
57132,0,0,0,47,94,0,0,0,15,0,0,0,CHMP1B;charged multivesicular body protein 1B,GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0015031//protein transport;GO:0000910//cytokinesis;GO:0045184//establishment of protein localization,GO:0019904//protein domain specific binding;GO:0005515//protein binding,K12197//Endocytosis
57134,89,0,0,0,5,0,31,0,27,0,0,0,"MAN1C1;mannosidase, alpha, class 1C, member 1",GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular vesicular exosome,GO:0043687//post-translational protein modification;GO:0006487//protein N-linked glycosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,"GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",K01230//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
57136,0,0,0,0,8,0,0,0,8,0,0,0,APMAP;adipocyte plasma membrane associated protein,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0009058//biosynthetic process,GO:0004064//arylesterase activity;GO:0016844//strictosidine synthase activity,K01757//Biosynthesis of secondary metabolites;Metabolic pathways;Indole alkaloid biosynthesis
57139,0,0,0,0,0,19,0,48,20,0,6,0,RGL3;ral guanine nucleotide dissociation stimulator-like 3,GO:0005622//intracellular,GO:0007264//small GTPase mediated signal transduction,GO:0017016//Ras GTPase binding;GO:0008321//Ral guanyl-nucleotide exchange factor activity,K08732//Colorectal cancer;Pathways in cancer;Pancreatic cancer
5714,0,22,1,9,37,0,0,0,0,0,0,0,"PSMD8;proteasome (prosome, macropain) 26S subunit, non-ATPase, 8",GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000502//proteasome complex;GO:0005838//proteasome regulatory particle;GO:0005654//nucleoplasm,"GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process;GO:0006915//apoptotic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",-,K03031//Epstein-Barr virus infection;Proteasome
57140,0,33,0,1,2,11,0,2,34,0,3,0,RNPEPL1;arginyl aminopeptidase (aminopeptidase B)-like 1,-,GO:0006508//proteolysis;GO:0019370//leukotriene biosynthetic process,GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
57142,109,24,79,2,55,0,2,0,53,0,0,0,RTN4;reticulon 4,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0043025//neuronal cell body;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005635//nuclear envelope;GO:0042995//cell projection;GO:0005622//intracellular,GO:0001525//angiogenesis;GO:0030334//regulation of cell migration;GO:0042981//regulation of apoptotic process;GO:2000172//regulation of branching morphogenesis of a nerve;GO:0030517//negative regulation of axon extension;GO:0071786//endoplasmic reticulum tubular network organization;GO:0007413//axonal fasciculation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0050770//regulation of axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0021801//cerebral cortex radial glia guided migration;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K00907//Calcium signaling pathway;Gastric acid secretion;Focal adhesion;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;K00688//Starch and sucrose metabolism;Insulin signaling pathway;K09880//Cysteine and methionine metabolism
57143,0,0,0,0,0,0,52,0,23,0,0,575,ADCK1;aarF domain containing kinase 1,GO:0005739//mitochondrion;GO:0005576//extracellular region,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
57144,62,0,0,0,0,20,0,0,39,0,24,0,PAK7;p21 protein (Cdc42/Rac)-activated kinase 7,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0007165//signal transduction;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0007613//memory;GO:0016049//cell growth;GO:0007626//locomotory behavior;GO:0016477//cell migration;GO:0007612//learning;GO:0006468//protein phosphorylation;GO:0007010//cytoskeleton organization;GO:0006915//apoptotic process;GO:0008283//cell proliferation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K05736//ErbB signaling pathway;Renal cell carcinoma;Focal adhesion;T cell receptor signaling pathway;Axon guidance;Regulation of actin cytoskeleton
57147,0,0,0,0,6,0,0,49,14,0,0,0,SCYL3;SCY1-like 3 (S. cerevisiae),GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005794//Golgi apparatus,GO:0016477//cell migration;GO:0006468//protein phosphorylation,GO:0005515//protein binding;GO:0016301//kinase activity;GO:0005524//ATP binding,-
57148,55,23,1,61,187,50,19,0,17,0,14,0,"RALGAPB;Ral GTPase activating protein, beta subunit (non-catalytic)",-,GO:0061024//membrane organization;GO:0032859//activation of Ral GTPase activity;GO:0060178//regulation of exocyst localization,GO:0046982//protein heterodimerization activity;GO:0017123//Ral GTPase activator activity,-
57149,1,44,0,0,115,0,0,99,3,0,6,0,LYRM1;LYR motif containing 1,GO:0005634//nucleus;GO:0005739//mitochondrion,-,-,-
5715,0,14,0,1,14,0,0,0,36,368,0,0,"PSMD9;proteasome (prosome, macropain) 26S subunit, non-ATPase, 9","GO:0005829//cytosol;GO:0008540//proteasome regulatory particle, base subcomplex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005838//proteasome regulatory particle","GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0046676//negative regulation of insulin secretion;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0032024//positive regulation of insulin secretion;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0070682//proteasome regulatory particle assembly;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0044281//small molecule metabolic process",GO:0005515//protein binding;GO:0043425//bHLH transcription factor binding;GO:0003713//transcription coactivator activity,-
57150,0,0,0,0,5,0,0,0,37,0,0,0,SMIM8;small integral membrane protein 8,GO:0016021//integral component of membrane,-,-,-
57151,0,0,0,0,1,0,0,0,0,0,9,0,LYZL6;lysozyme-like 6,GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process,GO:0003796//lysozyme activity,-
57152,0,0,0,0,0,12,13,0,0,0,0,0,SLURP1;secreted LY6/PLAUR domain containing 1,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0001775//cell activation;GO:0007155//cell adhesion,GO:0005125//cytokine activity,-
57153,87,0,31,1,7,17,1,0,24,0,6,0,"SLC44A2;solute carrier family 44 (choline transporter), member 2",GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0015871//choline transport;GO:0055085//transmembrane transport;GO:0006656//phosphatidylcholine biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction,GO:0015220//choline transmembrane transporter activity;GO:0004871//signal transducer activity,-
57154,0,65,0,52,65,26,32,117,16,162,98,0,SMURF1;SMAD specific E3 ubiquitin protein ligase 1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0016567//protein ubiquitination;GO:0030509//BMP signaling pathway;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0006611//protein export from nucleus;GO:0000209//protein polyubiquitination;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0034394//protein localization to cell surface;GO:0030514//negative regulation of BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007398//ectoderm development;GO:0032801//receptor catabolic process;GO:0030279//negative regulation of ossification;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030154//cell differentiation,GO:0070411//I-SMAD binding;GO:0070412//R-SMAD binding;GO:0048185//activin binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K04678//Endocytosis;Ubiquitin mediated proteolysis;TGF-beta signaling pathway
57156,0,0,0,0,0,48,0,75,45,0,0,674,TMEM63C;transmembrane protein 63C,GO:0016021//integral component of membrane,GO:0006812//cation transport,GO:0005227//calcium activated cation channel activity,K00728//Other types of O-glycan biosynthesis
57157,97,0,0,0,0,12,27,0,110,0,0,69,PHTF2;putative homeodomain transcription factor 2,GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
57158,0,0,11,0,0,15,28,63,9,0,0,0,JPH2;junctophilin 2,GO:0030018//Z disc;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0030314//junctional membrane complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0055074//calcium ion homeostasis;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0055024//regulation of cardiac muscle tissue development;GO:0070588//calcium ion transmembrane transport;GO:0060402//calcium ion transport into cytosol,"GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005515//protein binding;GO:0001786//phosphatidylserine binding;GO:0015278//calcium-release channel activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070300//phosphatidic acid binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding",K04575//Amyotrophic lateral sclerosis (ALS)
57159,0,0,0,0,0,0,0,0,5,0,0,0,TRIM54;tripartite motif containing 54,GO:0005875//microtubule associated complex;GO:0030018//Z disc;GO:0005874//microtubule,GO:0030154//cell differentiation;GO:0007165//signal transduction;GO:0007275//multicellular organismal development;GO:0007017//microtubule-based process;GO:0007026//negative regulation of microtubule depolymerization,GO:0008017//microtubule binding;GO:0008270//zinc ion binding;GO:0004871//signal transducer activity,-
5716,0,0,0,14,30,0,1,0,0,0,0,0,"PSMD10;proteasome (prosome, macropain) 26S subunit, non-ATPase, 10","GO:0005634//nucleus;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0008540//proteasome regulatory particle, base subcomplex","GO:0006915//apoptotic process;GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0000278//mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0016071//mRNA metabolic process;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0070682//proteasome regulatory particle assembly;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043409//negative regulation of MAPK cascade;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031398//positive regulation of protein ubiquitination;GO:0016070//RNA metabolic process;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0006521//regulation of cellular amino acid metabolic process;GO:0030307//positive regulation of cell growth;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process",GO:0008134//transcription factor binding;GO:0005515//protein binding,-
57161,62,0,0,3,23,20,20,0,0,0,3,0,PELI2;pellino E3 ubiquitin protein ligase family member 2,GO:0005829//cytosol,GO:0034166//toll-like receptor 10 signaling pathway;GO:0008063//Toll signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0016567//protein ubiquitination;GO:0045087//innate immune response;GO:0043410//positive regulation of MAPK cascade;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway,GO:0016874//ligase activity;GO:0005515//protein binding,-
57162,0,0,0,0,32,0,22,0,14,0,0,0,PELI1;pellino E3 ubiquitin protein ligase 1,GO:0005829//cytosol;GO:0005634//nucleus,GO:0034141//positive regulation of toll-like receptor 3 signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0031398//positive regulation of protein ubiquitination;GO:0043331//response to dsRNA;GO:0070936//protein K48-linked ubiquitination;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0008063//Toll signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0030890//positive regulation of B cell proliferation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0034134//toll-like receptor 2 signaling pathway;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034145//positive regulation of toll-like receptor 4 signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0001819//positive regulation of cytokine production,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
57165,0,0,0,0,0,17,0,0,2,0,0,0,"GJC2;gap junction protein, gamma 2, 47kDa",GO:0043209//myelin sheath;GO:0005922//connexon complex;GO:0016021//integral component of membrane,GO:0009636//response to toxic substance;GO:0055085//transmembrane transport;GO:0007267//cell-cell signaling;GO:0008219//cell death,GO:0005243//gap junction channel activity,-
57167,103,0,0,0,0,0,20,59,11,0,0,472,SALL4;spalt-like transcription factor 4,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000792//heterochromatin;GO:0043234//protein complex,"GO:0001843//neural tube closure;GO:0030326//embryonic limb morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003281//ventricular septum development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0006351//transcription, DNA-templated;GO:0001833//inner cell mass cell proliferation",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
57168,0,22,81,10,30,4,0,0,12,0,20,0,ASPHD2;aspartate beta-hydroxylase domain containing 2,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0018193//peptidyl-amino acid modification,GO:0046872//metal ion binding;GO:0051213//dioxygenase activity,-
57169,0,26,55,31,130,13,0,0,31,100,3,0,"ZNFX1;zinc finger, NFX1-type containing 1",-,-,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,K14326//RNA transport;mRNA surveillance pathway
5717,0,45,0,8,130,0,0,0,16,110,0,0,"PSMD11;proteasome (prosome, macropain) 26S subunit, non-ATPase, 11",GO:0000502//proteasome complex;GO:0005838//proteasome regulatory particle;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0044281//small molecule metabolic process;GO:0048863//stem cell differentiation;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0043248//proteasome assembly;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0005515//protein binding,K03036//Proteasome;Epstein-Barr virus infection
57171,0,0,0,0,0,0,0,0,7,0,0,0,DOLPP1;dolichyldiphosphatase 1,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0008610//lipid biosynthetic process;GO:0043687//post-translational protein modification;GO:0006487//protein N-linked glycosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0047874//dolichyldiphosphatase activity,K07252//N-Glycan biosynthesis
57172,0,0,0,0,0,36,0,0,65,0,0,0,CAMK1G;calcium/calmodulin-dependent protein kinase IG,GO:0043005//neuron projection;GO:0000139//Golgi membrane;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation,GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,-
57175,0,25,0,17,23,1,0,1,5,0,20,0,"CORO1B;coronin, actin binding protein, 1B",GO:0005884//actin filament;GO:0001725//stress fiber;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge,GO:0031529//ruffle organization;GO:0051017//actin filament bundle assembly;GO:0016477//cell migration;GO:0035767//endothelial cell chemotaxis;GO:0042060//wound healing;GO:1902463//protein localization to cell leading edge;GO:0030036//actin cytoskeleton organization;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0090135//actin filament branching,GO:0071933//Arp2/3 complex binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0051015//actin filament binding,-
57176,1,0,0,0,0,0,25,0,16,0,0,0,"VARS2;valyl-tRNA synthetase 2, mitochondrial",GO:0005739//mitochondrion,GO:0006438//valyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006450//regulation of translational fidelity,GO:0002161//aminoacyl-tRNA editing activity;GO:0004832//valine-tRNA ligase activity;GO:0005524//ATP binding,K01873//Biosynthesis of secondary metabolites;Glutathione metabolism;Aminoacyl-tRNA biosynthesis;Microbial metabolism in diverse environments;Pentose phosphate pathway;Metabolic pathways
57178,1,1,0,0,28,16,33,55,90,2,16,0,"ZMIZ1;zinc finger, MIZ-type containing 1",GO:0016607//nuclear speck;GO:0005737//cytoplasm,"GO:0048146//positive regulation of fibroblast proliferation;GO:0007296//vitellogenesis;GO:0006351//transcription, DNA-templated;GO:0007569//cell aging;GO:0048589//developmental growth;GO:0048844//artery morphogenesis;GO:0001570//vasculogenesis;GO:0003007//heart morphogenesis;GO:0001701//in utero embryonic development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0008270//zinc ion binding,K04706//Hepatitis C;Jak-STAT signaling pathway;Ubiquitin mediated proteolysis;K16063//Small cell lung cancer;Ubiquitin mediated proteolysis;Pathways in cancer;Jak-STAT signaling pathway;K16065//Ubiquitin mediated proteolysis;NF-kappa B signaling pathway;Jak-STAT signaling pathway
57179,0,2,1,0,27,0,12,0,13,0,18,0,KIAA1191;KIAA1191,GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
5718,0,33,0,19,69,13,0,0,0,0,0,0,"PSMD12;proteasome (prosome, macropain) 26S subunit, non-ATPase, 12",GO:0070062//extracellular vesicular exosome;GO:0022624//proteasome accessory complex;GO:0016020//membrane;GO:0005829//cytosol;GO:0005838//proteasome regulatory particle;GO:0000502//proteasome complex;GO:0005654//nucleoplasm,"GO:0044281//small molecule metabolic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0006915//apoptotic process",-,K03035//Proteasome;Epstein-Barr virus infection
57180,0,0,0,10,8,0,0,0,15,0,21,0,ACTR3B;ARP3 actin-related protein 3 homolog B (yeast),GO:0070062//extracellular vesicular exosome;GO:0042995//cell projection;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,-,GO:0005524//ATP binding;GO:0003779//actin binding,K05692//Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Viral myocarditis;Adherens junction;Phototransduction - fly;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;K12314//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction
57181,69,45,1,46,71,21,38,0,1,0,77,0,"SLC39A10;solute carrier family 39 (zinc transporter), member 10",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006829//zinc ion transport,GO:0046873//metal ion transmembrane transporter activity,-
57182,6,0,1,63,221,19,22,0,68,87,0,0,ANKRD50;ankyrin repeat domain 50,-,-,GO:0005515//protein binding,-
57184,0,33,50,78,181,0,0,0,15,0,12,0,"FAM219B;family with sequence similarity 219, member B",-,-,-,-
57185,0,30,2,126,377,0,29,0,38,0,0,0,NIPAL3;NIPA-like domain containing 3,GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
57186,106,30,2,38,124,0,25,53,50,0,2,137,"RALGAPA2;Ral GTPase activating protein, alpha subunit 2 (catalytic)",GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0032859//activation of Ral GTPase activity;GO:0061024//membrane organization,GO:0017123//Ral GTPase activator activity;GO:0046982//protein heterodimerization activity,K07207//mTOR signaling pathway;Insulin signaling pathway;p53 signaling pathway
57187,11,51,1,57,95,46,25,0,80,262,14,0,THOC2;THO complex 2,GO:0000445//THO complex part of transcription export complex;GO:0016607//nuclear speck;GO:0000346//transcription export complex,GO:0006397//mRNA processing;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0008380//RNA splicing;GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus,GO:0003723//RNA binding;GO:0005515//protein binding,K12879//Spliceosome;RNA transport
57189,0,38,1,53,154,9,40,2,42,0,17,0,KIAA1147;KIAA1147,-,-,-,-
5719,0,24,4,40,99,0,0,11,0,142,1,0,"PSMD13;proteasome (prosome, macropain) 26S subunit, non-ATPase, 13",GO:0022624//proteasome accessory complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005838//proteasome regulatory particle;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0044281//small molecule metabolic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0007127//meiosis I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006915//apoptotic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I",-,K03039//Proteasome;Epstein-Barr virus infection
57190,0,0,0,11,19,0,0,90,19,0,4,0,"SEPN1;selenoprotein N, 1",GO:0005789//endoplasmic reticulum membrane,-,GO:0005509//calcium ion binding;GO:0005515//protein binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion
57192,141,34,0,0,0,0,0,1,13,0,0,0,MCOLN1;mucolipin 1,GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0031902//late endosome membrane;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0055085//transmembrane transport;GO:0006879//cellular iron ion homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0051209//release of sequestered calcium ion into cytosol;GO:0033572//transferrin transport;GO:0034220//ion transmembrane transport;GO:0006812//cation transport,GO:0072345//NAADP-sensitive calcium-release channel activity;GO:0005261//cation channel activity,K04992//Lysosome
57194,49,41,0,0,0,57,1,54,54,246,0,0,"ATP10A;ATPase, class V, type 10A",GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0045332//phospholipid translocation;GO:0034220//ion transmembrane transport;GO:0008152//metabolic process;GO:0055085//transmembrane transport;GO:0008360//regulation of cell shape,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity,K01530//Purine metabolism
57198,52,0,25,11,41,30,18,0,99,0,22,2,"ATP8B2;ATPase, aminophospholipid transporter, class I, type 8B, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:0055085//transmembrane transport;GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity;GO:0000287//magnesium ion binding,K01530//Purine metabolism
572,0,38,0,1,0,0,0,0,0,0,20,0,BAD;BCL2-associated agonist of cell death,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane,GO:0097202//activation of cysteine-type endopeptidase activity;GO:0006915//apoptotic process;GO:0043200//response to amino acid;GO:0071316//cellular response to nicotine;GO:0019221//cytokine-mediated signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0010918//positive regulation of mitochondrial membrane potential;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0071396//cellular response to lipid;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0046031//ADP metabolic process;GO:0045582//positive regulation of T cell differentiation;GO:0001836//release of cytochrome c from mitochondria;GO:0032570//response to progesterone;GO:0034201//response to oleic acid;GO:0046902//regulation of mitochondrial membrane permeability;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0033574//response to testosterone;GO:0033133//positive regulation of glucokinase activity;GO:0045471//response to ethanol;GO:0097193//intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0042493//response to drug;GO:0046931//pore complex assembly;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0044342//type B pancreatic cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010508//positive regulation of autophagy;GO:0071456//cellular response to hypoxia;GO:0051384//response to glucocorticoid;GO:2000078//positive regulation of type B pancreatic cell development;GO:0045862//positive regulation of proteolysis;GO:0060139//positive regulation of apoptotic process by virus;GO:0046034//ATP metabolic process;GO:0051592//response to calcium ion;GO:0097190//apoptotic signaling pathway;GO:0032024//positive regulation of insulin secretion;GO:1901216//positive regulation of neuron death;GO:0006007//glucose catabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045579//positive regulation of B cell differentiation;GO:0032355//response to estradiol;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0042542//response to hydrogen peroxide;GO:0009749//response to glucose;GO:0071247//cellular response to chromate;GO:0019050//suppression by virus of host apoptotic process;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0042593//glucose homeostasis;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0060154//cellular process regulating host cell cycle in response to virus,GO:0008289//lipid binding;GO:0030346//protein phosphatase 2B binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0043422//protein kinase B binding;GO:0005543//phospholipid binding,K02158//Acute myeloid leukemia;Toxoplasmosis;Non-small cell lung cancer;Endometrial cancer;Melanoma;Hepatitis C;Neurotrophin signaling pathway;Alzheimer's disease;VEGF signaling pathway;Focal adhesion;Pathways in cancer;Insulin signaling pathway;Pancreatic cancer;Prostate cancer;Tuberculosis;Apoptosis;Amyotrophic lateral sclerosis (ALS);Chronic myeloid leukemia;ErbB signaling pathway;Colorectal cancer
5720,171,12,0,62,79,8,1,0,0,0,0,0,"PSME1;proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0000502//proteasome complex,"GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0006915//apoptotic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0006521//regulation of cellular amino acid metabolic process;GO:0000209//protein polyubiquitination;GO:0010950//positive regulation of endopeptidase activity;GO:0044281//small molecule metabolic process;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest",GO:0061133//endopeptidase activator activity,K06696//Proteasome;Antigen processing and presentation
57205,0,0,0,0,0,12,12,0,32,0,0,0,"ATP10D;ATPase, class V, type 10D",GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0034220//ion transmembrane transport;GO:0045332//phospholipid translocation;GO:0006812//cation transport;GO:0055085//transmembrane transport;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0019829//cation-transporting ATPase activity;GO:0004012//phospholipid-translocating ATPase activity,K01530//Purine metabolism
57209,0,1,0,4,82,13,62,0,55,0,17,0,ZNF248;zinc finger protein 248,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
5721,0,89,4,47,66,0,0,0,13,0,4,0,"PSME2;proteasome (prosome, macropain) activator subunit 2 (PA28 beta)",GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0008537//proteasome activator complex;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,"GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0044281//small molecule metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0042981//regulation of apoptotic process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I",-,K06697//Proteasome;Antigen processing and presentation
57210,1,0,0,4,4,34,41,0,50,111,16,211,"SLC45A4;solute carrier family 45, member 4",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
57211,0,0,0,0,0,0,0,33,15,294,4,0,GPR126;G protein-coupled receptor 126,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
57212,0,0,0,0,20,2,37,0,27,0,6,0,TP73-AS1;TP73 antisense RNA 1,GO:0005576//extracellular region,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
57213,0,0,0,28,29,0,58,0,66,0,0,0,SPRYD7;SPRY domain containing 7,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
57214,70,0,0,4,0,11,4,24,70,0,2,31,"CEMIP;cell migration inducing protein, hyaluronan binding",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum,GO:1900020//positive regulation of protein kinase C activity;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0007605//sensory perception of sound;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0090314//positive regulation of protein targeting to membrane;GO:0030214//hyaluronan catabolic process;GO:0030335//positive regulation of cell migration,GO:0005540//hyaluronic acid binding;GO:0032050//clathrin heavy chain binding;GO:0005515//protein binding;GO:0004415//hyalurononglucosaminidase activity;GO:0046923//ER retention sequence binding,K09666//Other types of O-glycan biosynthesis
57215,0,0,0,0,10,0,0,0,0,0,21,0,THAP11;THAP domain containing 11,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0045171//intercellular bridge,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
57216,0,0,0,0,11,0,9,0,61,0,0,0,VANGL2;VANGL planar cell polarity protein 2,GO:0001725//stress fiber;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005911//cell-cell junction;GO:0060187//cell pole;GO:0016328//lateral plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030134//ER to Golgi transport vesicle,GO:0001947//heart looping;GO:0090177//establishment of planar polarity involved in neural tube closure;GO:0048105//establishment of body hair planar orientation;GO:0042060//wound healing;GO:0032956//regulation of actin cytoskeleton organization;GO:0060993//kidney morphogenesis;GO:0035787//cell migration involved in kidney development;GO:0032835//glomerulus development;GO:0003150//muscular septum morphogenesis;GO:0060122//inner ear receptor stereocilium organization;GO:0043507//positive regulation of JUN kinase activity;GO:0003149//membranous septum morphogenesis;GO:0048546//digestive tract morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0003402//planar cell polarity pathway involved in axis elongation;GO:0007266//Rho protein signal transduction;GO:0060490//lateral sprouting involved in lung morphogenesis;GO:0060028//convergent extension involved in axis elongation;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity;GO:0001736//establishment of planar polarity;GO:0022007//convergent extension involved in neural plate elongation;GO:0001942//hair follicle development;GO:0030111//regulation of Wnt signaling pathway;GO:0036342//post-anal tail morphogenesis;GO:0061346//planar cell polarity pathway involved in heart morphogenesis;GO:0048103//somatic stem cell division;GO:0009952//anterior/posterior pattern specification;GO:0001843//neural tube closure;GO:0045176//apical protein localization;GO:0060489//planar dichotomous subdivision of terminal units involved in lung branching morphogenesis;GO:0090103//cochlea morphogenesis;GO:0035019//somatic stem cell maintenance;GO:0035058//nonmotile primary cilium assembly;GO:0060488//orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis,-,K04510//Wnt signaling pathway
57217,55,0,1,0,24,17,1,107,93,0,3,0,TTC7A;tetratricopeptide repeat domain 7A,-,GO:0006879//cellular iron ion homeostasis;GO:0030097//hemopoiesis,-,K09667//Other types of O-glycan biosynthesis
57221,1,321,14,245,653,0,36,74,107,23,60,0,KIAA1244;KIAA1244,GO:0016021//integral component of membrane;GO:0005802//trans-Golgi network,GO:0016192//vesicle-mediated transport;GO:0010923//negative regulation of phosphatase activity;GO:0032012//regulation of ARF protein signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005086//ARF guanyl-nucleotide exchange factor activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
57222,0,1,0,15,25,0,0,0,0,0,0,0,ERGIC1;endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1,GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0006888//ER to Golgi vesicle-mediated transport,GO:0005515//protein binding,-
57223,176,93,1,120,215,27,0,0,18,0,3,0,"SMEK2;SMEK homolog 2, suppressor of mek1 (Dictyostelium)",GO:0030289//protein phosphatase 4 complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005815//microtubule organizing center,GO:0006470//protein dephosphorylation;GO:0045722//positive regulation of gluconeogenesis;GO:0019216//regulation of lipid metabolic process,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
57224,0,13,0,14,6,49,0,0,45,0,14,0,NHSL1;NHS-like 1,-,-,-,-
57226,0,80,33,95,125,15,0,58,15,0,0,0,LYRM2;LYR motif containing 2,GO:0005739//mitochondrion,-,-,K12824//Spliceosome
57228,0,16,58,67,120,0,10,2,0,0,69,0,SMAGP;small cell adhesion glycoprotein,GO:0016021//integral component of membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005634//nucleus,-,-,K06576//Malaria
5723,0,0,0,15,9,13,22,0,0,0,0,0,PSPH;phosphoserine phosphatase,GO:0005829//cytosol;GO:0043005//neuron projection;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0006564//L-serine biosynthetic process;GO:0006563//L-serine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0031667//response to nutrient levels;GO:0008652//cellular amino acid biosynthetic process;GO:0009612//response to mechanical stimulus;GO:0016311//dephosphorylation;GO:0033574//response to testosterone,GO:0000287//magnesium ion binding;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0004647//phosphoserine phosphatase activity,"K01079//Arginine and proline metabolism;Biosynthesis of secondary metabolites;Methane metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Metabolic pathways"
57231,0,0,0,0,58,26,0,0,5,0,8,0,SNX14;sorting nexin 14,GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0035091//phosphatidylinositol binding,-
57232,0,0,54,34,41,0,22,0,55,0,26,0,ZNF630;zinc finger protein 630,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
57234,69,0,14,0,0,1,48,1,1,0,1,0,LINC00869;long intergenic non-protein coding RNA 869,-,-,-,-
5724,89,0,0,0,0,0,0,0,35,35,0,0,PTAFR;platelet-activating factor receptor,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0032959//inositol trisphosphate biosynthetic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001816//cytokine production;GO:0019221//cytokine-mediated signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0006954//inflammatory response,GO:0004930//G-protein coupled receptor activity;GO:0004992//platelet activating factor receptor activity;GO:0005543//phospholipid binding;GO:0001530//lipopolysaccharide binding;GO:0001875//lipopolysaccharide receptor activity,K04279//Calcium signaling pathway;Neuroactive ligand-receptor interaction;Staphylococcus aureus infection
5725,0,23,27,3,17,20,39,0,41,0,1,0,PTBP1;polypyrimidine tract binding protein 1,GO:0016020//membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0033119//negative regulation of RNA splicing;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0051148//negative regulation of muscle cell differentiation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0008187//poly-pyrimidine tract binding;GO:0036002//pre-mRNA binding;GO:0003723//RNA binding,-
5726,0,0,0,0,0,0,0,0,12,0,0,0,"TAS2R38;taste receptor, type 2, member 38",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0033038//bitter taste receptor activity,K08474//Taste transduction
5727,0,0,34,11,22,32,0,0,74,127,21,0,PTCH1;patched 1,GO:0014069//postsynaptic density;GO:0044295//axonal growth cone;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0043231//intracellular membrane-bounded organelle;GO:0030496//midbody;GO:0072372//primary cilium;GO:0044294//dendritic growth cone,GO:0009612//response to mechanical stimulus;GO:0010157//response to chlorate;GO:0045668//negative regulation of osteoblast differentiation;GO:0061053//somite development;GO:0010875//positive regulation of cholesterol efflux;GO:0060603//mammary gland duct morphogenesis;GO:0072203//cell proliferation involved in metanephros development;GO:0016485//protein processing;GO:0032526//response to retinoic acid;GO:0051782//negative regulation of cell division;GO:0007346//regulation of mitotic cell cycle;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0071397//cellular response to cholesterol;GO:0008544//epidermis development;GO:0043616//keratinocyte proliferation;GO:0008589//regulation of smoothened signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045879//negative regulation of smoothened signaling pathway;GO:0040015//negative regulation of multicellular organism growth;GO:0072001//renal system development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0072661//protein targeting to plasma membrane;GO:0060037//pharyngeal system development;GO:0001701//in utero embryonic development;GO:0042493//response to drug;GO:0035137//hindlimb morphogenesis;GO:0035108//limb morphogenesis;GO:0061005//cell differentiation involved in kidney development;GO:0007224//smoothened signaling pathway;GO:0032355//response to estradiol;GO:0021997//neural plate axis specification;GO:0003007//heart morphogenesis;GO:0001843//neural tube closure;GO:0048568//embryonic organ development;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0021522//spinal cord motor neuron differentiation;GO:0021532//neural tube patterning;GO:0009887//organ morphogenesis;GO:0007420//brain development;GO:0030326//embryonic limb morphogenesis;GO:0042593//glucose homeostasis;GO:0032880//regulation of protein localization;GO:0060644//mammary gland epithelial cell differentiation,GO:0097108//hedgehog family protein binding;GO:0008158//hedgehog receptor activity;GO:0005119//smoothened binding;GO:0005515//protein binding;GO:0005113//patched binding;GO:0008201//heparin binding;GO:0032403//protein complex binding;GO:0015485//cholesterol binding;GO:0030332//cyclin binding,K06225//Basal cell carcinoma;Hedgehog signaling pathway;Pathways in cancer
5728,0,12,0,80,226,15,41,0,60,4,6,0,PTEN;phosphatase and tensin homolog,GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0035749//myelin sheath adaxonal region;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0009898//cytoplasmic side of plasma membrane;GO:0045211//postsynaptic membrane;GO:0043005//neuron projection;GO:0005634//nucleus;GO:0042995//cell projection;GO:0043220//Schmidt-Lanterman incisure;GO:0005730//nucleolus;GO:0016605//PML body;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0009749//response to glucose;GO:0042711//maternal behavior;GO:0045087//innate immune response;GO:0060179//male mating behavior;GO:0043491//protein kinase B signaling;GO:0031658//negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0007507//heart development;GO:0001525//angiogenesis;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050765//negative regulation of phagocytosis;GO:0048854//brain morphogenesis;GO:0060134//prepulse inhibition;GO:0008283//cell proliferation;GO:0046685//response to arsenic-containing substance;GO:0060997//dendritic spine morphogenesis;GO:0030336//negative regulation of cell migration;GO:0051898//negative regulation of protein kinase B signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007568//aging;GO:0032286//central nervous system myelin maintenance;GO:0045475//locomotor rhythm;GO:0007613//memory;GO:0048853//forebrain morphogenesis;GO:0006470//protein dephosphorylation;GO:0035176//social behavior;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060291//long-term synaptic potentiation;GO:0006661//phosphatidylinositol biosynthetic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042493//response to drug;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0051895//negative regulation of focal adhesion assembly;GO:0007270//neuron-neuron synaptic transmission;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0061002//negative regulation of dendritic spine morphogenesis;GO:0048738//cardiac muscle tissue development;GO:0045471//response to ethanol;GO:0050771//negative regulation of axonogenesis;GO:0060024//rhythmic synaptic transmission;GO:0021542//dentate gyrus development;GO:2000808//negative regulation of synaptic vesicle clustering;GO:0043542//endothelial cell migration;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0045792//negative regulation of cell size;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0090071//negative regulation of ribosome biogenesis;GO:0006915//apoptotic process;GO:0007584//response to nutrient;GO:0046856//phosphatidylinositol dephosphorylation;GO:0033555//multicellular organismal response to stress;GO:0043065//positive regulation of apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007626//locomotory behavior;GO:0008284//positive regulation of cell proliferation;GO:0031642//negative regulation of myelination;GO:0032535//regulation of cellular component size;GO:0001933//negative regulation of protein phosphorylation;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0007417//central nervous system development;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0048015//phosphatidylinositol-mediated signaling;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0010043//response to zinc ion;GO:0007416//synapse assembly;GO:0016477//cell migration;GO:0007092//activation of mitotic anaphase-promoting complex activity;GO:0032355//response to estradiol;GO:0002902//regulation of B cell apoptotic process;GO:0010975//regulation of neuron projection development;GO:0060074//synapse maturation;GO:0043647//inositol phosphate metabolic process;GO:0060292//long term synaptic depression;GO:0050852//T cell receptor signaling pathway;GO:0090394//negative regulation of excitatory postsynaptic membrane potential;GO:0033198//response to ATP;GO:0044281//small molecule metabolic process;GO:0007611//learning or memory;GO:0021955//central nervous system neuron axonogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0097105//presynaptic membrane assembly;GO:0033032//regulation of myeloid cell apoptotic process;GO:0050821//protein stabilization;GO:0031647//regulation of protein stability;GO:0046855//inositol phosphate dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0097107//postsynaptic density assembly;GO:0050680//negative regulation of epithelial cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060736//prostate gland growth;GO:0046621//negative regulation of organ growth;GO:0090344//negative regulation of cell aging,"GO:0005161//platelet-derived growth factor receptor binding;GO:0019899//enzyme binding;GO:0004721//phosphoprotein phosphatase activity;GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0019901//protein kinase binding;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0030165//PDZ domain binding;GO:0010997//anaphase-promoting complex binding;GO:0005515//protein binding;GO:0051717//inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity;GO:0008289//lipid binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0051800//phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0000287//magnesium ion binding",K01110//Focal adhesion;Inositol phosphate metabolism;p53 signaling pathway;Glioma;Melanoma;Endometrial cancer;Small cell lung cancer;Prostate cancer;Tight junction;Phosphatidylinositol signaling system;Pathways in cancer
57282,0,0,0,0,0,0,0,0,89,0,0,0,"SLC4A10;solute carrier family 4, sodium bicarbonate transporter, member 10",GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006885//regulation of pH;GO:0006821//chloride transport;GO:0015701//bicarbonate transport;GO:0006811//ion transport;GO:0006814//sodium ion transport,GO:0005452//inorganic anion exchanger activity;GO:0015293//symporter activity,-
5729,0,0,0,0,0,22,11,0,0,0,0,0,PTGDR;prostaglandin D2 receptor (DP),GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0030238//male sex determination;GO:0006954//inflammatory response;GO:0030431//sleep;GO:0071799//cellular response to prostaglandin D stimulus;GO:0046085//adenosine metabolic process,GO:0005515//protein binding;GO:0001785//prostaglandin J receptor activity;GO:0004956//prostaglandin D receptor activity,K04332//Neuroactive ligand-receptor interaction
57291,0,0,0,5,26,0,0,0,30,0,0,0,DANCR;differentiation antagonizing non-protein coding RNA,-,-,-,-
573,0,14,0,22,61,0,0,0,1,0,0,0,BAG1;BCL2-associated athanogene,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043066//negative regulation of apoptotic process;GO:0070389//chaperone cofactor-dependent protein refolding;GO:0035556//intracellular signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process,GO:0051087//chaperone binding;GO:0005515//protein binding;GO:0005057//receptor signaling protein activity,K09555//Protein processing in endoplasmic reticulum
5730,0,0,0,0,0,19,0,0,10,0,0,0,PTGDS;prostaglandin D2 synthase 21kDa (brain),GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane;GO:0005791//rough endoplasmic reticulum;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane,"GO:0019371//cyclooxygenase pathway;GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0001516//prostaglandin biosynthetic process;GO:0019369//arachidonic acid metabolic process;GO:0045187//regulation of circadian sleep/wake cycle, sleep;GO:0006810//transport",GO:0005215//transporter activity;GO:0005504//fatty acid binding;GO:0004667//prostaglandin-D synthase activity;GO:0005501//retinoid binding,K01830//Metabolic pathways;Arachidonic acid metabolism
5731,0,0,0,0,0,0,0,3,0,0,0,0,"PTGER1;prostaglandin E receptor 1 (subtype EP1), 42kDa",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0032496//response to lipopolysaccharide,GO:0004957//prostaglandin E receptor activity,K04258//Calcium signaling pathway;Neuroactive ligand-receptor interaction
5732,0,0,0,0,0,0,0,0,32,0,0,0,"PTGER2;prostaglandin E receptor 2 (subtype EP2), 53kDa",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0032496//response to lipopolysaccharide;GO:0042127//regulation of cell proliferation;GO:0071380//cellular response to prostaglandin E stimulus;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004957//prostaglandin E receptor activity,K04259//Neuroactive ligand-receptor interaction
57325,0,0,0,11,34,0,0,0,0,0,6,0,CSRP2BP;CSRP2 binding protein,GO:0005634//nucleus;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0005737//cytoplasm,GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0000086//G2/M transition of mitotic cell cycle,GO:0004402//histone acetyltransferase activity;GO:0030274//LIM domain binding;GO:0005515//protein binding,-
57326,0,0,0,0,0,0,3,0,30,0,0,25,PBXIP1;pre-B-cell leukemia homeobox interacting protein 1,GO:0005874//microtubule;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007275//multicellular organismal development",GO:0005515//protein binding;GO:0003714//transcription corepressor activity,-
5733,68,0,0,0,0,40,32,65,117,61,0,0,PTGER3;prostaglandin E receptor 3 (subtype EP3),GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope,"GO:0006351//transcription, DNA-templated;GO:0031622//positive regulation of fever generation;GO:0030522//intracellular receptor signaling pathway;GO:0008219//cell death;GO:0007186//G-protein coupled receptor signaling pathway",GO:0004957//prostaglandin E receptor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,K04260//Calcium signaling pathway;Neuroactive ligand-receptor interaction
57332,0,0,0,0,0,0,28,0,16,0,0,0,CBX8;chromobox homolog 8,GO:0005654//nucleoplasm;GO:0000792//heterochromatin;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0035102//PRC1 complex;GO:0005730//nucleolus;GO:0031519//PcG protein complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0016574//histone ubiquitination",GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0003727//single-stranded RNA binding,-
57333,0,0,1,0,11,0,0,0,57,63,0,0,"RCN3;reticulocalbin 3, EF-hand calcium binding domain",GO:0005788//endoplasmic reticulum lumen,-,GO:0005515//protein binding;GO:0005509//calcium ion binding,K02183//Gastric acid secretion;Glioma;Melanogenesis;Alzheimer's disease;Neurotrophin signaling pathway;Olfactory transduction;Calcium signaling pathway;Salivary secretion;Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Oocyte meiosis;Vascular smooth muscle contraction;Tuberculosis;Pertussis;Alcoholism;Long-term potentiation;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Phototransduction;Insulin signaling pathway
57335,0,0,3,7,17,0,0,0,1,0,0,0,ZNF286A;zinc finger protein 286A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
57336,0,0,0,1,6,2,0,0,50,0,0,0,ZNF287;zinc finger protein 287,GO:0005634//nucleus,"GO:0042035//regulation of cytokine biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
57337,82,0,0,0,121,9,0,0,21,0,21,0,SENP7;SUMO1/sentrin specific peptidase 7,GO:0005634//nucleus;GO:0005622//intracellular,GO:0006508//proteolysis,GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding,-
57338,0,0,0,0,0,0,0,0,20,0,4,0,JPH3;junctophilin 3,GO:0005886//plasma membrane;GO:0030314//junctional membrane complex;GO:0016021//integral component of membrane;GO:0014701//junctional sarcoplasmic reticulum membrane,GO:0048168//regulation of neuronal synaptic plasticity;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0040011//locomotion;GO:0007613//memory;GO:0070588//calcium ion transmembrane transport;GO:0050885//neuromuscular process controlling balance;GO:0007612//learning;GO:0060402//calcium ion transport into cytosol;GO:0035640//exploration behavior,GO:0015278//calcium-release channel activity,K04575//Amyotrophic lateral sclerosis (ALS)
5734,0,0,0,0,0,0,22,0,75,0,0,0,PTGER4;prostaglandin E receptor 4 (subtype EP4),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0032496//response to lipopolysaccharide;GO:0050715//positive regulation of cytokine secretion;GO:0006955//immune response;GO:0007254//JNK cascade;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0050710//negative regulation of cytokine secretion;GO:0051492//regulation of stress fiber assembly;GO:0060348//bone development;GO:0033624//negative regulation of integrin activation;GO:0071260//cellular response to mechanical stimulus;GO:0070371//ERK1 and ERK2 cascade;GO:0050728//negative regulation of inflammatory response;GO:0030278//regulation of ossification;GO:0009612//response to mechanical stimulus;GO:0050729//positive regulation of inflammatory response;GO:0042093//T-helper cell differentiation;GO:2000420//negative regulation of eosinophil extravasation,GO:0005515//protein binding;GO:0004957//prostaglandin E receptor activity,K04261//Neuroactive ligand-receptor interaction
57343,0,0,0,0,0,0,0,1,27,0,0,0,ZNF304;zinc finger protein 304,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57348,0,0,0,0,0,24,0,27,0,0,0,0,TTYH1;tweety family member 1,GO:0030868//smooth endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0032433//filopodium tip;GO:0016021//integral component of membrane;GO:0031527//filopodium membrane;GO:0034707//chloride channel complex,GO:0016337//single organismal cell-cell adhesion;GO:0055085//transmembrane transport;GO:0006826//iron ion transport;GO:0044070//regulation of anion transport;GO:0034755//iron ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0046847//filopodium assembly;GO:0006821//chloride transport;GO:0007067//mitotic nuclear division;GO:0031589//cell-substrate adhesion;GO:1902476//chloride transmembrane transport,GO:0005509//calcium ion binding;GO:0072320//volume-sensitive chloride channel activity;GO:0005381//iron ion transmembrane transporter activity,-
57369,0,0,0,0,0,0,0,39,0,0,0,0,"GJD2;gap junction protein, delta 2, 36kDa",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005922//connexon complex,GO:0007601//visual perception;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport;GO:0001508//action potential,GO:0005243//gap junction channel activity,K07373//Gap junction
5737,0,0,0,0,0,7,0,0,86,0,2,0,PTGFR;prostaglandin F receptor (FP),GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0032496//response to lipopolysaccharide;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0043066//negative regulation of apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007567//parturition,GO:0004958//prostaglandin F receptor activity,K04262//Neuroactive ligand-receptor interaction;Calcium signaling pathway
57379,0,0,0,0,0,0,0,0,27,0,0,0,AICDA;activation-induced cytidine deaminase,GO:0000178//exosome (RNase complex);GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0016445//somatic diversification of immunoglobulins;GO:0030183//B cell differentiation;GO:0009972//cytidine deamination;GO:0071222//cellular response to lipopolysaccharide;GO:0080111//DNA demethylation;GO:0045190//isotype switching;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0090310//negative regulation of methylation-dependent chromatin silencing;GO:0006397//mRNA processing,GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0004126//cytidine deaminase activity,K10989//Primary immunodeficiency;Intestinal immune network for IgA production
5738,0,0,0,0,1,28,31,0,62,0,8,0,PTGFRN;prostaglandin F2 receptor inhibitor,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005789//endoplasmic reticulum membrane,GO:0034389//lipid particle organization,GO:0005515//protein binding,-
57380,0,0,1,6,31,0,10,33,14,0,6,0,MRS2;MRS2 magnesium transporter,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
57381,0,0,0,0,0,18,29,0,38,0,0,0,RHOJ;ras homolog family member J,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0008360//regulation of cell shape,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
5739,8,0,0,0,0,0,0,0,26,0,6,0,PTGIR;prostaglandin I2 (prostacyclin) receptor (IP),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005829//cytosol,"GO:0007267//cell-cell signaling;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0043547//positive regulation of GTPase activity;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030819//positive regulation of cAMP biosynthetic process",GO:0005085//guanyl-nucleotide exchange factor activity;GO:0004930//G-protein coupled receptor activity,K04263//Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction
57393,0,0,0,0,0,0,20,0,12,0,6,0,TMEM27;transmembrane protein 27,GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0035543//positive regulation of SNARE complex assembly;GO:0006508//proteolysis;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045956//positive regulation of calcium ion-dependent exocytosis,GO:0008237//metallopeptidase activity;GO:0005515//protein binding;GO:0008241//peptidyl-dipeptidase activity,K09708//Renin-angiotensin system;Protein digestion and absorption
57396,0,0,0,0,0,0,0,0,66,0,0,0,CLK4;CDC-like kinase 4,GO:0005634//nucleus,GO:0043484//regulation of RNA splicing;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity,K08823//Legionellosis
574,0,0,0,0,0,2,16,0,20,1,12,0,BAGE;B melanoma antigen,GO:0005576//extracellular region,-,-,K09188//Lysine degradation
5740,59,0,0,0,0,0,23,0,23,0,19,0,PTGIS;prostaglandin I2 (prostacyclin) synthase,GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005901//caveola;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0001516//prostaglandin biosynthetic process;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0050728//negative regulation of inflammatory response;GO:0035360//positive regulation of peroxisome proliferator activated receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:1900119//positive regulation of execution phase of apoptosis;GO:0045766//positive regulation of angiogenesis;GO:0071456//cellular response to hypoxia;GO:0006805//xenobiotic metabolic process;GO:0019371//cyclooxygenase pathway;GO:0044281//small molecule metabolic process,"GO:0004497//monooxygenase activity;GO:0020037//heme binding;GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0008116//prostaglandin-I synthase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",K01831//Arachidonic acid metabolism;Metabolic pathways
57402,0,0,0,0,8,0,0,0,0,0,3,0,S100A14;S100 calcium binding protein A14,GO:0070062//extracellular vesicular exosome;GO:0048471//perinuclear region of cytoplasm,GO:0032496//response to lipopolysaccharide;GO:0090026//positive regulation of monocyte chemotaxis;GO:0071624//positive regulation of granulocyte chemotaxis;GO:0055074//calcium ion homeostasis;GO:0006915//apoptotic process;GO:0042742//defense response to bacterium;GO:0034142//toll-like receptor 4 signaling pathway,GO:0005509//calcium ion binding;GO:0042379//chemokine receptor binding,-
574029,0,0,0,0,0,0,0,0,25,0,0,0,DUSP5P1;dual specificity phosphatase 5 pseudogene 1,-,-,-,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
57403,0,33,1,78,119,55,33,0,2,126,0,0,"RAB22A;RAB22A, member RAS oncogene family",GO:0015629//actin cytoskeleton;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0045335//phagocytic vesicle;GO:0010008//endosome membrane;GO:0001726//ruffle,GO:0006897//endocytosis;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0015031//protein transport;GO:0007032//endosome organization,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07891//Endocytosis
57404,0,159,122,117,244,17,11,211,82,110,103,1,"CYP20A1;cytochrome P450, family 20, subfamily A, polypeptide 1",GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process,"GO:0020037//heme binding;GO:0004497//monooxygenase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding",-
57405,0,0,0,0,0,0,21,0,0,0,0,0,"SPC25;SPC25, NDC80 kinetochore complex component",GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0031262//Ndc80 complex;GO:0005634//nucleus,GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation;GO:0007052//mitotic spindle organization,GO:0005515//protein binding,-
57406,0,0,0,0,0,23,0,3,37,0,3,0,ABHD6;abhydrolase domain containing 6,GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:2000124//regulation of endocannabinoid signaling pathway;GO:0008152//metabolic process;GO:0060292//long term synaptic depression;GO:0030336//negative regulation of cell migration,GO:0047372//acylglycerol lipase activity,K13700//Retrograde endocannabinoid signaling
57407,0,10,1,0,12,12,0,2,0,240,0,1,NMRAL1;NmrA-like family domain containing 1,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,-,-,-
57409,54,32,53,82,28,0,0,0,0,0,16,0,MIF4GD;MIF4G domain containing,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006417//regulation of translation,GO:0003723//RNA binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding,-
5741,0,0,0,0,0,0,14,0,15,0,0,0,PTH;parathyroid hormone,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0009967//positive regulation of signal transduction;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0042493//response to drug;GO:0007267//cell-cell signaling;GO:0006874//cellular calcium ion homeostasis;GO:0046058//cAMP metabolic process;GO:0010288//response to lead ion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045471//response to ethanol;GO:0071774//response to fibroblast growth factor;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0046326//positive regulation of glucose import;GO:0046686//response to cadmium ion;GO:0007266//Rho protein signal transduction;GO:0030501//positive regulation of bone mineralization;GO:0033280//response to vitamin D;GO:0071107//response to parathyroid hormone;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0045453//bone resorption;GO:0010468//regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0034645//cellular macromolecule biosynthetic process,GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0051428//peptide hormone receptor binding;GO:0005179//hormone activity;GO:0031857//type 1 parathyroid hormone receptor binding,-
57410,50,26,0,5,38,16,12,1,42,0,0,0,SCYL1;SCY1-like 1 (S. cerevisiae),GO:0030126//COPI vesicle coat;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,"GO:0006351//transcription, DNA-templated;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding,-
57412,0,0,0,0,0,6,0,0,0,0,2,0,AS3MT;arsenite methyltransferase,GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0018872//arsonoacetate metabolic process;GO:0009404//toxin metabolic process;GO:0032259//methylation,GO:0030791//arsenite methyltransferase activity;GO:0030792//methylarsonite methyltransferase activity,-
57415,0,0,1,22,45,11,21,0,1,0,0,0,C3orf14;chromosome 3 open reading frame 14,-,-,-,-
57418,51,0,0,0,8,0,54,0,31,0,0,0,WDR18;WD repeat domain 18,GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development,GO:0005515//protein binding,-
57419,0,0,0,0,0,26,0,40,27,1,1,0,"SLC24A3;solute carrier family 24 (sodium/potassium/calcium exchanger), member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0006813//potassium ion transport;GO:0006811//ion transport,"GO:0015293//symporter activity;GO:0008273//calcium, potassium:sodium antiporter activity",-
5742,0,0,0,0,0,0,33,0,53,0,4,0,PTGS1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase),GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0001750//photoreceptor outer segment,GO:0044281//small molecule metabolic process;GO:0019371//cyclooxygenase pathway;GO:0006805//xenobiotic metabolic process;GO:0042127//regulation of cell proliferation;GO:0006629//lipid metabolic process;GO:0006954//inflammatory response;GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0001516//prostaglandin biosynthetic process;GO:0008217//regulation of blood pressure,GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0004666//prostaglandin-endoperoxide synthase activity;GO:0051213//dioxygenase activity;GO:0046872//metal ion binding,K00509//Serotonergic synapse;Metabolic pathways;Arachidonic acid metabolism
5743,0,0,0,0,1,0,0,0,32,0,0,0,PTGS2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0043234//protein complex;GO:0043005//neuron projection,"GO:0008217//regulation of blood pressure;GO:0055114//oxidation-reduction process;GO:0031915//positive regulation of synaptic plasticity;GO:0030728//ovulation;GO:0032227//negative regulation of synaptic transmission, dopaminergic;GO:0034612//response to tumor necrosis factor;GO:0050873//brown fat cell differentiation;GO:0001516//prostaglandin biosynthetic process;GO:0090336//positive regulation of brown fat cell differentiation;GO:0046697//decidualization;GO:0071260//cellular response to mechanical stimulus;GO:0006928//cellular component movement;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0043065//positive regulation of apoptotic process;GO:0010042//response to manganese ion;GO:0006954//inflammatory response;GO:0033280//response to vitamin D;GO:0035633//maintenance of blood-brain barrier;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0034644//cellular response to UV;GO:0050727//regulation of inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0007612//learning;GO:0071318//cellular response to ATP;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0045987//positive regulation of smooth muscle contraction;GO:0071636//positive regulation of transforming growth factor beta production;GO:0042493//response to drug;GO:0044281//small molecule metabolic process;GO:0019371//cyclooxygenase pathway;GO:0051384//response to glucocorticoid;GO:0071456//cellular response to hypoxia;GO:0006693//prostaglandin metabolic process;GO:0019372//lipoxygenase pathway;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0019369//arachidonic acid metabolic process;GO:0006979//response to oxidative stress;GO:0045986//negative regulation of smooth muscle contraction;GO:0030282//bone mineralization;GO:0045907//positive regulation of vasoconstriction;GO:0070542//response to fatty acid;GO:0019233//sensory perception of pain;GO:0045786//negative regulation of cell cycle;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051926//negative regulation of calcium ion transport;GO:0032355//response to estradiol;GO:0007613//memory;GO:0009750//response to fructose;GO:0008285//negative regulation of cell proliferation;GO:0007566//embryo implantation;GO:0042640//anagen;GO:0090271//positive regulation of fibroblast growth factor production;GO:0031394//positive regulation of prostaglandin biosynthetic process;GO:0090362//positive regulation of platelet-derived growth factor production;GO:0010226//response to lithium ion;GO:0031622//positive regulation of fever generation;GO:0001525//angiogenesis;GO:0045429//positive regulation of nitric oxide biosynthetic process",GO:0050473//arachidonate 15-lipoxygenase activity;GO:0020037//heme binding;GO:0008289//lipid binding;GO:0019899//enzyme binding;GO:0004666//prostaglandin-endoperoxide synthase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0004601//peroxidase activity,K11987//VEGF signaling pathway;Metabolic pathways;Arachidonic acid metabolism;Leishmaniasis;Small cell lung cancer;Retrograde endocannabinoid signaling;Serotonergic synapse;NF-kappa B signaling pathway;Pathways in cancer
5744,0,0,0,0,0,17,38,0,19,44,0,0,PTHLH;parathyroid hormone-like hormone,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005730//nucleolus;GO:0005576//extracellular region;GO:0005794//Golgi apparatus,GO:0048286//lung alveolus development;GO:0060659//nipple sheath formation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007267//cell-cell signaling;GO:0043129//surfactant homeostasis;GO:0032331//negative regulation of chondrocyte differentiation;GO:0007565//female pregnancy;GO:0008284//positive regulation of cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0046058//cAMP metabolic process;GO:0007492//endoderm development;GO:0008544//epidermis development;GO:0001958//endochondral ossification;GO:0016485//protein processing;GO:0060649//mammary gland bud elongation;GO:0002076//osteoblast development;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030855//epithelial cell differentiation;GO:0001501//skeletal system development;GO:0010468//regulation of gene expression,GO:0005179//hormone activity;GO:0051428//peptide hormone receptor binding,-
574407,115,3,0,0,24,5,0,62,10,0,1,0,C1orf145;chromosome 1 open reading frame 145,-,-,-,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM);K00747//Metabolic pathways;Glycosaminoglycan biosynthesis - chondroitin sulfate;K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Calcium signaling pathway;Gastric acid secretion
574413,0,0,0,0,0,0,0,0,12,0,0,0,MIR409;microRNA 409,-,-,-,-
574436,0,0,0,0,0,35,0,0,0,0,0,0,MIR485;microRNA 485,-,-,-,-
574453,0,0,0,0,0,0,0,0,14,0,0,0,MIR495;microRNA 495,-,-,-,-
574455,0,0,0,0,0,14,0,0,0,0,0,0,MIR193B;microRNA 193b,-,-,-,-
574459,0,0,0,0,0,1,0,0,0,0,0,0,MIR512-2;microRNA 512-2,-,-,-,-
57446,24,0,1,61,273,15,0,0,44,0,6,0,NDRG3;NDRG family member 3,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0030308//negative regulation of cell growth;GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation
574461,0,0,0,0,0,3,0,0,0,0,0,0,MIR520E;microRNA 520e,-,-,-,-
574463,0,0,0,0,0,0,0,0,8,0,3,0,MIR519E;microRNA 519e,-,-,-,-
574467,0,0,0,0,0,38,0,0,0,0,0,0,MIR520A;microRNA 520a,-,-,-,-
57447,0,3,42,15,147,35,0,52,0,0,0,0,NDRG2;NDRG family member 2,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0021762//substantia nigra development;GO:0016055//Wnt signaling pathway;GO:0090361//regulation of platelet-derived growth factor production;GO:0030154//cell differentiation;GO:0001818//negative regulation of cytokine production;GO:0010574//regulation of vascular endothelial growth factor production;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0048662//negative regulation of smooth muscle cell proliferation,GO:0005515//protein binding,-
574473,0,0,0,0,0,0,0,0,7,0,0,0,MIR520B;microRNA 520b,-,-,-,-
57448,168,164,1,153,498,99,31,39,95,9,24,56,BIRC6;baculoviral IAP repeat containing 6,GO:0016020//membrane;GO:0005768//endosome;GO:0030496//midbody;GO:0005802//trans-Golgi network;GO:0000922//spindle pole;GO:0005815//microtubule organizing center,GO:0010951//negative regulation of endopeptidase activity;GO:0060711//labyrinthine layer development;GO:0006915//apoptotic process;GO:0060712//spongiotrophoblast layer development;GO:0006468//protein phosphorylation;GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0042127//regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0007067//mitotic nuclear division;GO:0032465//regulation of cytokinesis;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway,GO:0016881//acid-amino acid ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0004869//cysteine-type endopeptidase inhibitor activity,K10586//Ubiquitin mediated proteolysis
574482,0,0,0,0,0,0,0,0,12,0,0,0,MIR520D;microRNA 520d,-,-,-,-
57449,0,0,0,0,0,13,14,0,95,0,0,0,"PLEKHG5;pleckstrin homology domain containing, family G (with RhoGef domain) member 5",GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0048471//perinuclear region of cytoplasm;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0030139//endocytic vesicle;GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035767//endothelial cell chemotaxis;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway,GO:0004871//signal transducer activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12331//Vascular smooth muscle contraction;K05160//Cytokine-cytokine receptor interaction;K12330//Vascular smooth muscle contraction;Regulation of actin cytoskeleton
574491,0,0,0,0,0,0,0,0,6,0,0,0,MIR518A2;microRNA 518a-2,-,-,-,-
574499,0,0,0,0,0,0,0,0,0,0,0,199,MIR516A2;microRNA 516a-2,-,-,-,-
5745,0,0,0,0,0,0,51,0,77,0,0,0,PTH1R;parathyroid hormone 1 receptor,GO:0031526//brush border membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005634//nucleus,"GO:0007568//aging;GO:0001501//skeletal system development;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030282//bone mineralization;GO:0045453//bone resorption;GO:0002076//osteoblast development;GO:0048469//cell maturation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0008284//positive regulation of cell proliferation;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0002062//chondrocyte differentiation",GO:0017046//peptide hormone binding;GO:0004991//parathyroid hormone receptor activity;GO:0005515//protein binding;GO:0043621//protein self-association,K04585//Neuroactive ligand-receptor interaction;Endocrine and other factor-regulated calcium reabsorption
574503,0,0,0,0,0,0,0,0,0,0,3,0,MIR501;microRNA 501,-,-,-,-
574504,0,0,0,0,0,0,0,0,7,0,0,0,MIR502;microRNA 502,-,-,-,-
57451,60,0,44,18,13,1,6,0,150,0,25,22,TENM2;teneurin transmembrane protein 2,GO:0045211//postsynaptic membrane;GO:0005783//endoplasmic reticulum;GO:0043005//neuron projection;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030175//filopodium;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0030426//growth cone;GO:0043197//dendritic spine;GO:0005911//cell-cell junction;GO:0016605//PML body;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016337//single organismal cell-cell adhesion;GO:0007411//axon guidance;GO:0097264//self proteolysis;GO:0051491//positive regulation of filopodium assembly;GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0007165//signal transduction",GO:0005102//receptor binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0050839//cell adhesion molecule binding,K06252//ECM-receptor interaction;Focal adhesion
574516,0,0,0,0,0,0,0,0,10,0,0,0,MIR514A1;microRNA 514a-1,-,-,-,-
57452,66,0,0,0,6,0,0,0,81,0,14,0,GALNT16;polypeptide N-acetylgalactosaminyltransferase 16,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome,GO:0006486//protein glycosylation,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
57453,222,0,0,0,0,34,0,0,34,0,1,0,DSCAML1;Down syndrome cell adhesion molecule like 1,GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0007409//axonogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0070593//dendrite self-avoidance;GO:0007420//brain development;GO:0048704//embryonic skeletal system morphogenesis;GO:0007417//central nervous system development;GO:0001709//cell fate determination;GO:0009953//dorsal/ventral pattern formation;GO:0007162//negative regulation of cell adhesion,GO:0042803//protein homodimerization activity,-
574538,0,0,0,15,0,70,32,42,7,0,0,0,LOC574538;uncharacterized LOC574538,-,-,-,K12495//Endocytosis
57455,0,0,43,15,1,28,37,1,21,0,0,0,"REXO1;REX1, RNA exonuclease 1 homolog (S. cerevisiae)",GO:0005730//nucleolus;GO:0005634//nucleus,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding,K14570//Ribosome biogenesis in eukaryotes
57456,0,24,0,29,131,0,18,9,2,0,21,0,KIAA1143;KIAA1143,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K13962//Gastric acid secretion;K11447//Transcriptional misregulation in cancer
57459,25,12,0,15,62,47,1,0,17,0,26,0,GATAD2B;GATA zinc finger domain containing 2B,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0043234//protein complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0043044//ATP-dependent chromatin remodeling;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding,-
5746,0,0,0,5,0,22,0,4,34,0,5,0,PTH2R;parathyroid hormone 2 receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004991//parathyroid hormone receptor activity,K04586//Neuroactive ligand-receptor interaction
57460,0,185,4,96,278,13,14,0,57,0,9,12,"PPM1H;protein phosphatase, Mg2+/Mn2+ dependent, 1H",-,GO:0016311//dephosphorylation,GO:0004721//phosphoprotein phosphatase activity,-
57461,0,0,0,0,0,20,0,59,18,0,0,0,ISY1;ISY1 splicing factor homolog (S. cerevisiae),GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12870//Spliceosome
57462,0,0,0,0,0,7,27,0,24,87,0,0,KIAA1161;KIAA1161,GO:0016021//integral component of membrane;GO:0031965//nuclear membrane,GO:0051897//positive regulation of protein kinase B signaling;GO:0005975//carbohydrate metabolic process;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0048741//skeletal muscle fiber development,"GO:0004553//hydrolase activity, hydrolyzing O-glycosyl compounds",K01187//Starch and sucrose metabolism;Riboflavin metabolism;Metabolic pathways;Galactose metabolism;K12316//Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism;Lysosome;K05546//Protein processing in endoplasmic reticulum;N-Glycan biosynthesis;Metabolic pathways
57463,0,0,0,0,0,0,0,0,11,0,0,0,AMIGO1;adhesion molecule with Ig-like domain 1,GO:0030424//axon;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042552//myelination;GO:0050772//positive regulation of axonogenesis;GO:0007413//axonal fasciculation;GO:0007409//axonogenesis;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,-,K06839//Axon guidance
57464,0,0,0,0,0,0,0,0,45,93,1,0,STRIP2;striatin interacting protein 2,GO:0005737//cytoplasm,GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
57465,79,1,1,0,15,13,13,0,13,142,14,0,"TBC1D24;TBC1 domain family, member 24",GO:0005737//cytoplasm,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly;GO:0031175//neuron projection development,GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K02155//Collecting duct acid secretion;Rheumatoid arthritis;Phagosome;Tuberculosis;Synaptic vesicle cycle;Oxidative phosphorylation;Metabolic pathways;Epithelial cell signaling in Helicobacter pylori infection;Lysosome;Vibrio cholerae infection
57466,122,0,6,12,1,7,0,33,36,249,0,0,SCAF4;SR-related CTD-associated factor 4,GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
57467,0,0,0,0,1,18,17,0,37,0,0,0,HHATL;hedgehog acyltransferase-like,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm,GO:0060262//negative regulation of N-terminal protein palmitoylation,-,-
57468,64,0,0,0,0,20,0,232,54,0,30,0,"SLC12A5;solute carrier family 12 (potassium/chloride transporter), member 5",GO:0016021//integral component of membrane;GO:0043198//dendritic shaft;GO:0005886//plasma membrane;GO:0043025//neuronal cell body,GO:0006810//transport;GO:0035264//multicellular organism growth;GO:0006811//ion transport;GO:0006813//potassium ion transport;GO:0055085//transmembrane transport;GO:0007612//learning;GO:0007268//synaptic transmission;GO:0006873//cellular ion homeostasis;GO:0042493//response to drug;GO:0040040//thermosensory behavior;GO:1902476//chloride transmembrane transport,GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding,K14427//GABAergic synapse
57469,0,0,0,0,0,0,20,40,33,0,0,0,PNMAL2;paraneoplastic Ma antigen family-like 2,-,-,-,-
5747,82,59,1,63,168,0,1,2,31,0,1,25,PTK2;protein tyrosine kinase 2,GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0001725//stress fiber;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030027//lamellipodium;GO:0016324//apical plasma membrane;GO:0005938//cell cortex;GO:0005856//cytoskeleton,GO:0032319//regulation of Rho GTPase activity;GO:2000811//negative regulation of anoikis;GO:0008360//regulation of cell shape;GO:0001890//placenta development;GO:0043066//negative regulation of apoptotic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0045087//innate immune response;GO:0009790//embryo development;GO:0051493//regulation of cytoskeleton organization;GO:0008284//positive regulation of cell proliferation;GO:0010594//regulation of endothelial cell migration;GO:0001525//angiogenesis;GO:0048013//ephrin receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0060396//growth hormone receptor signaling pathway;GO:0001764//neuron migration;GO:0007596//blood coagulation;GO:0001934//positive regulation of protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0000226//microtubule cytoskeleton organization;GO:0048870//cell motility;GO:0042127//regulation of cell proliferation;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0051964//negative regulation of synapse assembly;GO:0030168//platelet activation;GO:0003007//heart morphogenesis;GO:0022408//negative regulation of cell-cell adhesion;GO:0038007//netrin-activated signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0050771//negative regulation of axonogenesis;GO:0030335//positive regulation of cell migration;GO:0007411//axon guidance;GO:0030198//extracellular matrix organization;GO:0030010//establishment of cell polarity;GO:0007172//signal complex assembly;GO:0021955//central nervous system neuron axonogenesis;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0001570//vasculogenesis;GO:0006915//apoptotic process;GO:0051893//regulation of focal adhesion assembly;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0046621//negative regulation of organ growth;GO:0045667//regulation of osteoblast differentiation;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0040023//establishment of nucleus localization;GO:0045860//positive regulation of protein kinase activity;GO:0046777//protein autophosphorylation;GO:0043542//endothelial cell migration;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007229//integrin-mediated signaling pathway,GO:0042169//SH2 domain binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004871//signal transducer activity;GO:0008432//JUN kinase binding;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity,K05725//Amoebiasis;Focal adhesion;VEGF signaling pathway;ErbB signaling pathway;Regulation of actin cytoskeleton;Small cell lung cancer;Leukocyte transendothelial migration;Transcriptional misregulation in cancer;Bacterial invasion of epithelial cells;Pathways in cancer;Chemokine signaling pathway;Axon guidance
57470,0,18,0,12,54,15,10,0,37,0,0,284,LRRC47;leucine rich repeat containing 47,-,GO:0008152//metabolic process,GO:0004826//phenylalanine-tRNA ligase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K01890//Aminoacyl-tRNA biosynthesis;ABC transporters;Bacterial secretion system
57471,0,0,0,0,0,11,0,0,3,0,0,0,"ERMN;ermin, ERM-like protein",GO:0033269//internode region of axon;GO:0033270//paranode region of axon;GO:0005856//cytoskeleton;GO:0043025//neuronal cell body;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0043209//myelin sheath;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome,GO:0031344//regulation of cell projection organization;GO:0001763//morphogenesis of a branching structure;GO:0007015//actin filament organization;GO:0008360//regulation of cell shape,GO:0051015//actin filament binding,-
57473,61,29,0,5,0,17,0,42,59,77,13,0,ZNF512B;zinc finger protein 512B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57474,0,0,0,0,45,0,8,0,69,0,1,0,ZNF490;zinc finger protein 490,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
57475,0,8,37,62,83,12,0,0,32,0,8,0,"PLEKHH1;pleckstrin homology domain containing, family H (with MyTH4 domain) member 1",GO:0005856//cytoskeleton,-,-,K12559//Fc gamma R-mediated phagocytosis
57476,123,0,0,0,0,36,54,0,43,1,0,381,GRAMD1B;GRAM domain containing 1B,GO:0016020//membrane;GO:0016021//integral component of membrane,-,-,-
57477,0,0,1,0,31,16,0,0,40,0,0,0,SHROOM4;shroom family member 4,GO:0009925//basal plasma membrane;GO:0016460//myosin II complex;GO:0001725//stress fiber;GO:0030864//cortical actin cytoskeleton;GO:0031941//filamentous actin;GO:0015629//actin cytoskeleton;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0009898//cytoplasmic side of plasma membrane,GO:0007015//actin filament organization;GO:0007420//brain development;GO:0050890//cognition;GO:0000902//cell morphogenesis;GO:0030036//actin cytoskeleton organization,GO:0051015//actin filament binding,K11447//Transcriptional misregulation in cancer;K00901//Glycerophospholipid metabolism;Phosphatidylinositol signaling system;Glycerolipid metabolism;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
57478,152,2,0,25,12,38,0,48,83,0,0,0,USP31;ubiquitin specific peptidase 31,GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0004843//ubiquitin-specific protease activity,-
57479,53,0,0,0,0,0,0,0,30,0,0,0,PRR12;proline rich 12,-,-,GO:0003677//DNA binding,-
57480,0,0,0,0,0,0,2,0,59,0,0,244,"PLEKHG1;pleckstrin homology domain containing, family G (with RhoGef domain) member 1",-,GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K05769//Regulation of actin cytoskeleton
57481,0,0,0,0,0,27,0,66,63,0,0,0,KIAA1210;KIAA1210,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K14443//RNA degradation
57482,60,0,10,2,26,0,13,43,28,0,0,0,KIAA1211;KIAA1211,-,-,-,K04574//Amyotrophic lateral sclerosis (ALS)
57484,51,0,0,0,30,16,34,0,83,23,0,0,RNF150;ring finger protein 150,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
57486,69,38,0,35,53,22,33,2,29,17,0,0,NLN;neurolysin (metallopeptidase M3 family),GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane,GO:0006508//proteolysis,GO:0046872//metal ion binding;GO:0004222//metalloendopeptidase activity;GO:0042277//peptide binding,K01393//Renin-angiotensin system
57488,0,0,0,2,0,29,65,28,77,0,0,0,ESYT2;extended synaptotagmin-like protein 2,GO:0005887//integral component of plasma membrane;GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0016020//membrane;GO:0044232//organelle membrane contact site;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane,GO:0006869//lipid transport;GO:0006897//endocytosis,GO:0035091//phosphatidylinositol binding;GO:0005509//calcium ion binding;GO:0008429//phosphatidylethanolamine binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0031210//phosphatidylcholine binding;GO:0005544//calcium-dependent phospholipid binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K15290//Synaptic vesicle cycle
57489,0,0,0,12,3,0,0,34,9,0,13,0,ODF2L;outer dense fiber of sperm tails 2-like,GO:0005813//centrosome,-,-,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K04257//Olfactory transduction;K12478//Tuberculosis;Phagosome;Endocytosis
57491,405,0,0,0,0,15,0,0,66,0,9,0,AHRR;aryl-hydrocarbon receptor repressor,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0033235//positive regulation of protein sumoylation;GO:0007165//signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0004871//signal transducer activity,-
57492,0,16,1,21,82,0,25,121,91,0,3,34,ARID1B;AT rich interactive domain 1B (SWI1-like),GO:0005730//nucleolus;GO:0016514//SWI/SNF complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0048096//chromatin-mediated maintenance of transcription;GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0005515//protein binding,-
57493,0,0,0,6,0,0,0,0,62,6,5,0,HEG1;heart development protein with EGF-like domains 1,GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0005911//cell-cell junction,GO:0007043//cell-cell junction assembly;GO:0003209//cardiac atrium morphogenesis;GO:0050878//regulation of body fluid levels;GO:0001570//vasculogenesis;GO:0009791//post-embryonic development;GO:0001886//endothelial cell morphogenesis;GO:0060039//pericardium development;GO:0003281//ventricular septum development;GO:0003017//lymph circulation;GO:0001701//in utero embryonic development;GO:0048845//venous blood vessel morphogenesis;GO:0001945//lymph vessel development;GO:0030324//lung development;GO:0035264//multicellular organism growth,GO:0005509//calcium ion binding,K02599//Prion diseases;Dorso-ventral axis formation;Notch signaling pathway
57494,0,0,0,0,0,0,0,0,1,0,0,0,RIMKLB;ribosomal modification protein rimK-like family member B,GO:0005737//cytoplasm,GO:0006464//cellular protein modification process,GO:0046872//metal ion binding;GO:0072590//N-acetyl-L-aspartate-L-glutamate ligase activity;GO:0072591//citrate-L-glutamate ligase activity;GO:0005524//ATP binding,-
57495,0,0,0,0,8,69,36,54,67,0,2,0,NWD2;NACHT and WD repeat domain containing 2,-,-,-,K02084//Parkinson's disease;Huntington's disease;Tuberculosis;Legionellosis;Small cell lung cancer;Apoptosis;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;p53 signaling pathway
57496,104,13,1,32,178,11,60,89,108,0,0,0,MKL2;MKL/myocardin-like 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001701//in utero embryonic development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048514//blood vessel morphogenesis;GO:0003007//heart morphogenesis;GO:0051145//smooth muscle cell differentiation;GO:0001889//liver development;GO:0045844//positive regulation of striated muscle tissue development;GO:0048568//embryonic organ development;GO:0006351//transcription, DNA-templated;GO:0007517//muscle organ development;GO:0048738//cardiac muscle tissue development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003676//nucleic acid binding;GO:0003713//transcription coactivator activity;GO:0003779//actin binding,-
57497,0,0,0,0,0,15,48,20,22,0,16,0,LRFN2;leucine rich repeat and fibronectin type III domain containing 2,GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,-,-,K07523//Axon guidance
57498,103,0,31,0,7,72,0,0,84,201,15,0,"KIDINS220;kinase D-interacting substrate, 220kDa",GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0043234//protein complex,GO:0048813//dendrite morphogenesis;GO:0000186//activation of MAPKK activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016482//cytoplasmic transport;GO:0001701//in utero embryonic development;GO:1990090//cellular response to nerve growth factor stimulus;GO:0038180//nerve growth factor signaling pathway;GO:0010976//positive regulation of neuron projection development,GO:0030165//PDZ domain binding,K12460//Neurotrophin signaling pathway
575,0,0,0,0,0,24,20,0,56,0,34,15,BAI1;brain-specific angiogenesis inhibitor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0007218//neuropeptide signaling pathway;GO:0007422//peripheral nervous system development;GO:0007165//signal transduction;GO:0007409//axonogenesis;GO:0016525//negative regulation of angiogenesis,GO:0004930//G-protein coupled receptor activity,K04596//p53 signaling pathway
57501,0,0,0,0,0,0,0,0,0,0,2,0,KIAA1257;KIAA1257,-,-,-,-
57502,0,0,0,0,0,6,20,50,22,0,7,0,"NLGN4X;neuroligin 4, X-linked",GO:0014069//postsynaptic density;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0009986//cell surface;GO:0005887//integral component of plasma membrane;GO:0060076//excitatory synapse,GO:0090394//negative regulation of excitatory postsynaptic membrane potential;GO:0035265//organ growth;GO:0050808//synapse organization;GO:0007612//learning;GO:0035176//social behavior;GO:0030182//neuron differentiation;GO:0003360//brainstem development;GO:0097105//presynaptic membrane assembly;GO:0030534//adult behavior;GO:0071625//vocalization behavior;GO:0045216//cell-cell junction organization;GO:0007158//neuron cell-cell adhesion;GO:0021549//cerebellum development,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0031404//chloride ion binding;GO:0004872//receptor activity;GO:0042043//neurexin family protein binding,K07378//Cell adhesion molecules (CAMs)
57504,0,0,0,0,11,15,17,49,13,22,0,0,"MTA3;metastasis associated 1 family, member 3",GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,"GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding,-
57505,0,0,23,3,0,14,18,119,26,0,30,287,"AARS2;alanyl-tRNA synthetase 2, mitochondrial",GO:0005739//mitochondrion,GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression;GO:0070143//mitochondrial alanyl-tRNA aminoacylation;GO:0033108//mitochondrial respiratory chain complex assembly,GO:0000049//tRNA binding;GO:0005524//ATP binding;GO:0008270//zinc ion binding;GO:0004813//alanine-tRNA ligase activity,K01872//Microbial metabolism in diverse environments;Aminoacyl-tRNA biosynthesis;Purine metabolism
57506,215,85,1,10,57,0,49,70,163,0,7,1,MAVS;mitochondrial antiviral signaling protein,GO:0005778//peroxisomal membrane;GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion,"GO:0071360//cellular response to exogenous dsRNA;GO:0045087//innate immune response;GO:0032728//positive regulation of interferon-beta production;GO:0032480//negative regulation of type I interferon production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032727//positive regulation of interferon-alpha production;GO:0071651//positive regulation of chemokine (C-C motif) ligand 5 production;GO:0042742//defense response to bacterium;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0016032//viral process;GO:0007165//signal transduction;GO:0071660//positive regulation of IP-10 production;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0002218//activation of innate immune response;GO:0045071//negative regulation of viral genome replication;GO:1900063//regulation of peroxisome organization;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002230//positive regulation of defense response to virus by host;GO:0039529//RIG-I signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0001934//positive regulation of protein phosphorylation",GO:0019901//protein kinase binding;GO:0050700//CARD domain binding;GO:0005515//protein binding;GO:0004871//signal transducer activity,K12648//Measles;Influenza A;RIG-I-like receptor signaling pathway;Herpes simplex infection;Hepatitis C;Cytosolic DNA-sensing pathway
57507,0,0,0,0,23,9,20,71,26,245,0,0,ZNF608;zinc finger protein 608,-,-,GO:0046872//metal ion binding,K10847//Nucleotide excision repair
57508,0,0,0,0,0,17,22,0,41,0,10,0,INTS2;integrator complex subunit 2,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005622//intracellular;GO:0032039//integrator complex;GO:0031965//nuclear membrane,GO:0016180//snRNA processing,GO:0005515//protein binding,-
57509,0,101,1,52,151,34,60,0,1,0,0,0,MTUS1;microtubule associated tumor suppressor 1,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005819//spindle;GO:0005739//mitochondrion;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005874//microtubule,GO:0071375//cellular response to peptide hormone stimulus;GO:0010758//regulation of macrophage chemotaxis,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
57510,88,104,0,121,184,23,0,82,34,46,25,52,XPO5;exportin 5,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0031047//gene silencing by RNA;GO:0006611//protein export from nucleus;GO:0010467//gene expression,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008536//Ran GTPase binding;GO:0000049//tRNA binding;GO:0003723//RNA binding;GO:0008565//protein transporter activity,K14289//RNA transport
57511,30,0,1,6,47,0,10,1,57,0,0,0,COG6;component of oligomeric golgi complex 6,GO:0000139//Golgi membrane;GO:0017119//Golgi transport complex,GO:0070085//glycosylation;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport,-,-
57512,186,0,0,0,0,5,21,0,52,1,19,652,GPR158;G protein-coupled receptor 158,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0072659//protein localization to plasma membrane,GO:0004930//G-protein coupled receptor activity,-
57513,0,0,0,5,0,13,0,0,29,0,36,0,CASKIN2;CASK interacting protein 2,GO:0005737//cytoplasm,-,-,-
57514,0,0,0,0,0,19,22,0,64,0,11,0,ARHGAP31;Rho GTPase activating protein 31,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030027//lamellipodium,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0017124//SH3 domain binding;GO:0005096//GTPase activator activity,K04450//Influenza A;Alcoholism;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Epstein-Barr virus infection;Amphetamine addiction;MAPK signaling pathway;K08878//Pathways in cancer;Chronic myeloid leukemia
57515,0,1,0,16,5,11,0,0,3,0,3,0,SERINC1;serine incorporator 1,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006665//sphingolipid metabolic process;GO:0051347//positive regulation of transferase activity;GO:0015825//L-serine transport;GO:0008654//phospholipid biosynthetic process;GO:0006658//phosphatidylserine metabolic process,GO:0015194//L-serine transmembrane transporter activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
57519,0,0,0,0,12,35,89,0,174,0,16,0,STARD9;StAR-related lipid transfer (START) domain containing 9,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0005871//kinesin complex;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0051225//spindle assembly;GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0008289//lipid binding;GO:0005524//ATP binding;GO:0008574//plus-end-directed microtubule motor activity;GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity,-
57520,102,0,0,1,0,10,69,31,131,0,2,0,"HECW2;HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
57521,180,33,0,0,2,52,94,93,89,0,0,0,"RPTOR;regulatory associated protein of MTOR, complex 1",GO:0005764//lysosome;GO:0031931//TORC1 complex;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol,GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0001938//positive regulation of endothelial cell proliferation;GO:0008286//insulin receptor signaling pathway;GO:0008361//regulation of cell size;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0016049//cell growth;GO:0071230//cellular response to amino acid stimulus;GO:0032008//positive regulation of TOR signaling;GO:0031929//TOR signaling;GO:0031669//cellular response to nutrient levels;GO:0007050//cell cycle arrest,GO:0001030//RNA polymerase III type 1 promoter DNA binding;GO:0019901//protein kinase binding;GO:0001031//RNA polymerase III type 2 promoter DNA binding;GO:0032403//protein complex binding;GO:0001032//RNA polymerase III type 3 promoter DNA binding;GO:0005515//protein binding;GO:0001156//TFIIIC-class transcription factor binding;GO:0071889//14-3-3 protein binding,K07204//mTOR signaling pathway;Insulin signaling pathway
57522,177,0,51,0,1,5,3,0,50,0,0,0,SRGAP1;SLIT-ROBO Rho GTPase activating protein 1,GO:0005829//cytosol,GO:0016477//cell migration;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction;GO:0007411//axon guidance,GO:0005100//Rho GTPase activator activity;GO:0017048//Rho GTPase binding;GO:0005515//protein binding,K07526//Axon guidance
57523,0,0,0,0,0,3,0,0,39,107,6,0,NYNRIN;NYN domain and retroviral integrase containing,GO:0016021//integral component of membrane,GO:0015074//DNA integration,GO:0003676//nucleic acid binding,K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption
57524,0,158,58,123,321,15,91,178,126,0,400,61,CASKIN1;CASK interacting protein 1,GO:0005737//cytoplasm,GO:0007165//signal transduction,GO:0005515//protein binding,-
57526,0,0,0,0,0,26,16,0,41,0,5,0,PCDH19;protocadherin 19,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
57528,84,0,0,0,0,0,0,0,57,106,0,1,KCTD16;potassium channel tetramerization domain containing 16,GO:0043235//receptor complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0051260//protein homooligomerization,-,-
57529,113,0,0,0,0,6,8,0,26,152,0,0,RGAG1;retrotransposon gag domain containing 1,-,-,-,K10955//Amoebiasis;Vibrio cholerae infection
5753,0,0,0,0,0,29,4,37,10,0,12,0,PTK6;protein tyrosine kinase 6,GO:0001726//ruffle;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010976//positive regulation of neuron projection development;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0046777//protein autophosphorylation;GO:0042506//tyrosine phosphorylation of Stat5 protein;GO:0016477//cell migration;GO:0006468//protein phosphorylation;GO:0045926//negative regulation of growth;GO:0071300//cellular response to retinoic acid;GO:0042503//tyrosine phosphorylation of Stat3 protein;GO:0060575//intestinal epithelial cell differentiation,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,-
57530,178,20,0,24,15,0,0,52,27,0,28,0,CGN;cingulin,GO:0016459//myosin complex;GO:0005923//tight junction;GO:0030054//cell junction,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008152//metabolic process,GO:0003779//actin binding;GO:0005515//protein binding;GO:0003774//motor activity,K06102//Tight junction
57531,0,0,0,33,23,0,0,1,48,0,0,0,HACE1;HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1,GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0061025//membrane fusion;GO:0070936//protein K48-linked ubiquitination;GO:0016567//protein ubiquitination;GO:0007030//Golgi organization;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030334//regulation of cell migration;GO:0007049//cell cycle;GO:0016601//Rac protein signal transduction;GO:0006355//regulation of transcription, DNA-templated",GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0048365//Rac GTPase binding;GO:0017137//Rab GTPase binding,-
57532,0,77,0,101,187,18,27,62,97,51,0,0,NUFIP2;nuclear fragile X mental retardation protein interacting protein 2,GO:0042788//polysomal ribosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,-,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
57533,0,50,2,12,197,8,13,129,33,0,21,260,"TBC1D14;TBC1 domain family, member 14",GO:0055037//recycling endosome;GO:0005776//autophagic vacuole;GO:0005794//Golgi apparatus,GO:1902017//regulation of cilium assembly;GO:0010507//negative regulation of autophagy;GO:0032851//positive regulation of Rab GTPase activity;GO:0071955//recycling endosome to Golgi transport;GO:2000785//regulation of autophagic vacuole assembly,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K08187//Protein digestion and absorption;K13136//RNA transport
57534,71,99,0,44,189,0,0,95,46,0,0,1,MIB1;mindbomb E3 ubiquitin protein ligase 1,GO:0014069//postsynaptic density;GO:0031410//cytoplasmic vesicle;GO:0005813//centrosome;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0045665//negative regulation of neuron differentiation;GO:0001947//heart looping;GO:0045807//positive regulation of endocytosis;GO:0001841//neural tube formation;GO:0016567//protein ubiquitination;GO:0001701//in utero embryonic development;GO:0001756//somitogenesis;GO:0007219//Notch signaling pathway;GO:0001568//blood vessel development,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
57535,127,0,0,9,9,9,18,54,24,6,9,0,KIAA1324;KIAA1324,GO:0005887//integral component of plasma membrane;GO:0005802//trans-Golgi network;GO:0005764//lysosome;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005770//late endosome;GO:0070062//extracellular vesicular exosome,GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0016236//macroautophagy;GO:2000786//positive regulation of autophagic vacuole assembly;GO:0009267//cellular response to starvation,GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
57536,0,8,22,0,0,77,20,0,14,0,7,0,KIAA1328;KIAA1328,-,-,-,-
57537,0,0,0,0,0,19,25,0,35,0,20,0,SORCS2;sortilin-related VPS10 domain containing receptor 2,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity,K12388//Lysosome;Neurotrophin signaling pathway
57538,123,0,0,0,0,22,20,51,112,0,13,152,ALPK3;alpha-kinase 3,GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0007507//heart development,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
57539,33,0,23,11,36,73,26,0,77,108,0,0,WDR35;WD repeat domain 35,GO:0036064//ciliary basal body;GO:0030991//intraciliary transport particle A;GO:0005930//axoneme;GO:0005813//centrosome,GO:0042384//cilium assembly;GO:0035721//intraciliary retrograde transport,-,-
5754,69,0,0,7,0,16,11,317,41,0,19,0,PTK7;protein tyrosine kinase 7,GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction,GO:0007155//cell adhesion;GO:0071300//cellular response to retinoic acid;GO:0001843//neural tube closure;GO:0010976//positive regulation of neuron projection development;GO:0003401//axis elongation;GO:0090103//cochlea morphogenesis;GO:0060026//convergent extension;GO:0007165//signal transduction;GO:0016477//cell migration;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0060070//canonical Wnt signaling pathway;GO:0042060//wound healing;GO:0001736//establishment of planar polarity;GO:0060484//lung-associated mesenchyme development,GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0005515//protein binding,-
57540,70,0,0,0,0,13,0,59,0,97,26,688,PTCHD2;patched domain containing 2,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031965//nuclear membrane,GO:0007224//smoothened signaling pathway;GO:0042632//cholesterol homeostasis;GO:0032368//regulation of lipid transport,GO:0008158//hedgehog receptor activity,-
57541,5,0,0,9,20,32,0,0,45,0,13,0,ZNF398;zinc finger protein 398,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
57542,0,1,0,23,91,5,25,0,21,0,9,0,KLHL42;kelch-like family member 42,GO:0005819//spindle;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032886//regulation of microtubule-based process;GO:0007067//mitotic nuclear division,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
57544,0,0,0,14,0,0,0,0,24,42,0,0,TXNDC16;thioredoxin domain containing 16,GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen,GO:0045454//cell redox homeostasis,GO:0005515//protein binding,K08056//Protein processing in endoplasmic reticulum;Antigen processing and presentation;K09580//Protein processing in endoplasmic reticulum
57545,0,1,0,36,49,10,52,0,65,0,14,0,CC2D2A;coiled-coil and C2 domain containing 2A,GO:0035869//ciliary transition zone;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0036038//TCTN-B9D complex,GO:0042384//cilium assembly;GO:0060271//cilium morphogenesis;GO:0007224//smoothened signaling pathway,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption
57546,0,32,1,4,52,0,0,0,12,0,0,0,PDP2;pyruvate dehyrogenase phosphatase catalytic subunit 2,GO:0005759//mitochondrial matrix,GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process;GO:0035970//peptidyl-threonine dephosphorylation;GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate,GO:0046872//metal ion binding;GO:0004741//[pyruvate dehydrogenase (lipoamide)] phosphatase activity;GO:0004724//magnesium-dependent protein serine/threonine phosphatase activity,-
57547,71,0,0,0,19,0,22,0,13,0,0,0,ZNF624;zinc finger protein 624,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
57549,7,0,0,0,0,5,35,1,19,0,36,0,"IGSF9;immunoglobulin superfamily, member 9",GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0030054//cell junction;GO:0016021//integral component of membrane,GO:0016358//dendrite development,-,K06755//Axon guidance;K06754//Axon guidance
57551,0,155,0,24,187,0,38,53,48,216,0,0,TAOK1;TAO kinase 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006974//cellular response to DNA damage stimulus;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0097194//execution phase of apoptosis;GO:0051493//regulation of cytoskeleton organization;GO:0031577//spindle checkpoint;GO:0031572//G2 DNA damage checkpoint;GO:0006281//DNA repair;GO:0046330//positive regulation of JNK cascade;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle,GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0016740//transferase activity;GO:0004674//protein serine/threonine kinase activity,K04429//MAPK signaling pathway
57552,40,0,0,0,17,15,35,0,14,0,0,0,NCEH1;neutral cholesterol ester hydrolase 1,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0006470//protein dephosphorylation;GO:0016042//lipid catabolic process;GO:0006805//xenobiotic metabolic process,GO:0042301//phosphate ion binding;GO:0017171//serine hydrolase activity;GO:0052689//carboxylic ester hydrolase activity,K14349//Bile secretion
57553,0,9,0,5,9,47,98,0,108,132,7,0,"MICAL3;microtubule associated monooxygenase, calponin and LIM domain containing 3",GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0055114//oxidation-reduction process;GO:0006887//exocytosis;GO:0030042//actin filament depolymerization;GO:0007010//cytoskeleton organization,"GO:0008270//zinc ion binding;GO:0071949//FAD binding;GO:0003779//actin binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",K06115//Tight junction
57554,0,0,0,7,0,54,15,0,62,0,0,0,LRRC7;leucine rich repeat containing 7,GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,-,GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway
57555,74,40,0,0,1,10,0,38,2,14,2,0,NLGN2;neuroligin 2,GO:0042734//presynaptic membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0060077//inhibitory synapse;GO:0005887//integral component of plasma membrane,"GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0097151//positive regulation of inhibitory postsynaptic membrane potential;GO:0097104//postsynaptic membrane assembly;GO:0050804//regulation of synaptic transmission;GO:0051965//positive regulation of synapse assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0019233//sensory perception of pain;GO:0007416//synapse assembly;GO:0097116//gephyrin clustering;GO:0050808//synapse organization;GO:0045217//cell-cell junction maintenance;GO:0035418//protein localization to synapse;GO:0016337//single organismal cell-cell adhesion;GO:0050885//neuromuscular process controlling balance;GO:0072553//terminal button organization;GO:0097105//presynaptic membrane assembly;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0035641//locomotory exploration behavior;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0007158//neuron cell-cell adhesion",GO:0050839//cell adhesion molecule binding;GO:0004872//receptor activity;GO:0042043//neurexin family protein binding,K07378//Cell adhesion molecules (CAMs)
57558,43,0,0,0,0,0,21,43,16,107,0,0,USP35;ubiquitin specific peptidase 35,-,GO:0016579//protein deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004843//ubiquitin-specific protease activity,-
57559,0,0,0,0,0,16,32,120,13,0,0,0,STAMBPL1;STAM binding protein-like 1,GO:0016020//membrane,GO:0006508//proteolysis,GO:0008237//metallopeptidase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
5756,0,12,0,13,125,17,0,0,65,0,0,0,TWF1;twinfilin actin-binding protein 1,GO:0030175//filopodium;GO:0030016//myofibril;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0032587//ruffle membrane;GO:0005925//focal adhesion;GO:0048471//perinuclear region of cytoplasm,GO:0051016//barbed-end actin filament capping;GO:0043538//regulation of actin phosphorylation;GO:0030837//negative regulation of actin filament polymerization;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0042989//sequestering of actin monomers,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005524//ATP binding;GO:0003785//actin monomer binding;GO:0004713//protein tyrosine kinase activity",-
57560,0,0,0,9,66,25,0,0,5,0,0,0,IFT80;intraflagellar transport 80,GO:0030992//intraciliary transport particle B;GO:0005929//cilium;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0001649//osteoblast differentiation;GO:0007224//smoothened signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:0060349//bone morphogenesis;GO:0042384//cilium assembly;GO:0002062//chondrocyte differentiation;GO:0045880//positive regulation of smoothened signaling pathway,-,K04508//Wnt signaling pathway
57561,0,0,0,0,33,0,18,0,23,0,0,0,ARRDC3;arrestin domain containing 3,GO:0005768//endosome;GO:0005886//plasma membrane,GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0001659//temperature homeostasis;GO:0044252//negative regulation of multicellular organismal metabolic process;GO:0043588//skin development;GO:0060613//fat pad development;GO:0031651//negative regulation of heat generation;GO:0090327//negative regulation of locomotion involved in locomotory behavior;GO:0071879//positive regulation of adrenergic receptor signaling pathway,GO:0005515//protein binding;GO:0031699//beta-3 adrenergic receptor binding,-
57562,65,0,0,0,0,25,16,0,51,0,2,0,KIAA1377;KIAA1377,GO:0030496//midbody,-,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
57563,90,0,0,31,66,0,0,0,43,0,0,0,KLHL8;kelch-like family member 8,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination,-,-
57565,0,13,0,0,0,0,0,0,26,0,0,0,KLHL14;kelch-like family member 14,GO:0043025//neuronal cell body;GO:0005789//endoplasmic reticulum membrane;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,-,-,-
57567,11,0,0,0,15,0,14,0,19,180,6,0,ZNF319;zinc finger protein 319,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57568,121,1,0,0,8,10,37,158,60,137,0,165,SIPA1L2;signal-induced proliferation-associated 1 like 2,-,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K08013//Leukocyte transendothelial migration
57569,0,0,0,0,0,0,39,0,61,0,0,0,ARHGAP20;Rho GTPase activating protein 20,GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K08773//Pathways in cancer;Pancreatic cancer;K07526//Axon guidance
5757,0,46,1,135,307,0,0,0,17,0,0,0,"PTMA;prothymosin, alpha",GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated",-,-
57570,67,49,0,3,12,1,0,0,59,0,0,0,TRMT5;tRNA methyltransferase 5,GO:0005634//nucleus;GO:0005759//mitochondrial matrix,GO:0030488//tRNA methylation,GO:0052906//tRNA (guanine(37)-N(1))-methyltransferase activity,-
57571,0,0,0,0,0,6,28,0,41,161,14,0,CARNS1;carnosine synthase 1,-,GO:0006200//ATP catabolic process,GO:0016887//ATPase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding,K14755//Histidine metabolism;beta-Alanine metabolism;Arginine and proline metabolism
57572,0,1,0,0,0,41,3,0,88,94,46,0,DOCK6;dedicator of cytokinesis 6,GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0007596//blood coagulation;GO:0043547//positive regulation of GTPase activity,GO:0005085//guanyl-nucleotide exchange factor activity,K13708//Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Focal adhesion;Shigellosis
57573,0,0,0,0,0,0,0,0,25,0,0,0,ZNF471;zinc finger protein 471,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
57574,0,5,0,7,11,0,0,0,57,0,1,0,"MARCH4;membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase",GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005795//Golgi stack,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
57575,100,0,30,0,0,0,0,0,17,145,22,0,PCDH10;protocadherin 10,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
57576,0,0,1,1,0,10,52,28,31,0,0,0,KIF17;kinesin family member 17,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0030992//intraciliary transport particle B;GO:0005871//kinesin complex,GO:0022008//neurogenesis;GO:0007018//microtubule-based movement;GO:0016192//vesicle-mediated transport;GO:0006200//ATP catabolic process;GO:0030030//cell projection organization;GO:0015031//protein transport;GO:0031503//protein complex localization;GO:0008152//metabolic process,GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding;GO:0008017//microtubule binding;GO:0016887//ATPase activity,-
57577,0,0,0,7,0,0,0,0,7,93,15,0,KIAA1407;KIAA1407,-,-,-,"K13524//GABAergic synapse;Metabolic pathways;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Propanoate metabolism;Butanoate metabolism;Alanine, aspartate and glutamate metabolism"
57578,70,0,0,0,1,18,0,19,91,1,47,564,UNC79;unc-79 homolog (C. elegans),GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0035264//multicellular organism growth;GO:0048149//behavioral response to ethanol;GO:0055085//transmembrane transport,-,-
57579,0,160,7,205,688,0,21,0,81,0,2,0,"FAM135A;family with sequence similarity 135, member A",-,-,-,-
57580,0,0,0,0,2,13,32,48,77,0,9,0,"PREX1;phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1",GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0043198//dendritic shaft;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030426//growth cone;GO:0005737//cytoplasm,GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0032855//positive regulation of Rac GTPase activity;GO:0030041//actin filament polymerization;GO:0030593//neutrophil chemotaxis;GO:0042119//neutrophil activation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006801//superoxide metabolic process;GO:0035556//intracellular signal transduction;GO:0050773//regulation of dendrite development;GO:0030833//regulation of actin filament polymerization;GO:0030217//T cell differentiation,GO:0019899//enzyme binding;GO:0005100//Rho GTPase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005543//phospholipid binding,K12365//Chemokine signaling pathway
57582,0,0,0,0,0,12,14,48,53,96,28,0,"KCNT1;potassium channel, subfamily T, member 1",GO:0008076//voltage-gated potassium channel complex,GO:0071805//potassium ion transmembrane transport,GO:0015269//calcium-activated potassium channel activity;GO:0005249//voltage-gated potassium channel activity,-
57583,0,1,0,0,43,33,17,0,40,0,0,0,TMEM181;transmembrane protein 181,GO:0016021//integral component of membrane,GO:0009405//pathogenesis,GO:0015643//toxic substance binding,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
57584,301,0,1,0,41,28,27,2,134,163,0,285,ARHGAP21;Rho GTPase activating protein 21,GO:0005856//cytoskeleton;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0030659//cytoplasmic vesicle membrane;GO:0000139//Golgi membrane,GO:0043547//positive regulation of GTPase activity;GO:0007030//Golgi organization;GO:0007165//signal transduction;GO:0051684//maintenance of Golgi location;GO:0072384//organelle transport along microtubule;GO:0051683//establishment of Golgi localization,GO:0005096//GTPase activator activity;GO:0005515//protein binding,K08878//Pathways in cancer;Chronic myeloid leukemia;K07526//Axon guidance;K04450//MAPK signaling pathway;Amphetamine addiction;Epstein-Barr virus infection;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;Alcoholism;Influenza A
57585,81,0,0,0,53,31,0,1,70,0,33,1,"CRAMP1L;Crm, cramped-like (Drosophila)",GO:0005634//nucleus,-,GO:0003682//chromatin binding;GO:0003677//DNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
57586,0,0,59,7,9,0,30,64,34,0,0,0,SYT13;synaptotagmin XIII,GO:0005887//integral component of plasma membrane;GO:0030133//transport vesicle,GO:0016192//vesicle-mediated transport,-,K15290//Synaptic vesicle cycle
57587,0,0,0,60,57,0,25,0,12,0,0,0,KIAA1430;KIAA1430,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
57589,0,3,0,6,20,38,0,0,66,0,49,0,KIAA1432;KIAA1432,GO:0043234//protein complex;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005829//cytosol,"GO:0032851//positive regulation of Rab GTPase activity;GO:0042147//retrograde transport, endosome to Golgi",GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0017137//Rab GTPase binding,-
57590,0,1,0,53,135,17,26,12,23,0,10,0,WDFY1;WD repeat and FYVE domain containing 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005769//early endosome,-,GO:0008270//zinc ion binding;GO:0005545//1-phosphatidylinositol binding,K03362//Ubiquitin mediated proteolysis;Shigellosis;Circadian rhythm - mammal;Wnt signaling pathway;Oocyte meiosis;Hedgehog signaling pathway;K12182//Endocytosis;Phagosome
57591,0,0,0,0,0,18,5,0,40,0,2,0,MKL1;megakaryoblastic leukemia (translocation) 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:2001234//negative regulation of apoptotic signaling pathway;GO:0010735//positive regulation of transcription via serum response element binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051145//smooth muscle cell differentiation",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043522//leucine zipper domain binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003785//actin monomer binding;GO:0003713//transcription coactivator activity;GO:0003779//actin binding,-
57592,0,0,0,9,0,0,38,228,86,33,36,1,ZNF687;zinc finger protein 687,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57593,0,0,0,0,14,16,45,0,13,0,0,0,EBF4;early B-cell factor 4,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0046983//protein dimerization activity,-
57594,0,0,0,1,31,31,0,49,78,0,1,0,HOMEZ;homeobox and leucine zipper encoding,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
57595,81,0,0,0,0,18,0,0,34,0,13,0,PDZD4;PDZ domain containing 4,GO:0005938//cell cortex,-,-,-
57596,59,0,0,0,0,1,17,0,0,0,0,0,BEGAIN;brain-enriched guanylate kinase-associated,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0016020//membrane,-,GO:0005515//protein binding,K06105//Tight junction
57597,0,0,0,0,14,43,28,104,105,61,17,256,BAHCC1;BAH domain and coiled-coil containing 1,-,-,GO:0003682//chromatin binding,K00558//Metabolic pathways;Cysteine and methionine metabolism;Folate biosynthesis
57599,0,44,0,8,112,0,0,0,2,0,0,0,WDR48;WD repeat domain 48,GO:0005764//lysosome;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,GO:0048568//embryonic organ development;GO:0043588//skin development;GO:0035264//multicellular organism growth;GO:0072520//seminiferous tubule development;GO:0048872//homeostasis of number of cells;GO:0000724//double-strand break repair via homologous recombination;GO:0007283//spermatogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0016032//viral process;GO:0048705//skeletal system morphogenesis;GO:0007338//single fertilization;GO:0016579//protein deubiquitination,GO:0005515//protein binding,K15361//Fanconi anemia pathway
576,91,0,0,0,0,19,43,47,28,0,13,0,BAI2;brain-specific angiogenesis inhibitor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007422//peripheral nervous system development;GO:0016525//negative regulation of angiogenesis;GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
57600,0,0,0,0,53,22,0,0,0,0,4,0,FNIP2;folliculin interacting protein 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001932//regulation of protein phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding,-
57602,0,24,0,0,7,15,0,1,37,52,17,0,USP36;ubiquitin specific peptidase 36,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0016579//protein deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0044822//poly(A) RNA binding;GO:0004843//ubiquitin-specific protease activity,-
57604,0,0,0,0,0,0,10,0,91,0,10,0,KIAA1456;KIAA1456,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
57606,188,22,3,59,228,26,38,170,13,1,13,1,"SLAIN2;SLAIN motif family, member 2",GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end,GO:0031122//cytoplasmic microtubule organization;GO:0007020//microtubule nucleation;GO:0031116//positive regulation of microtubule polymerization,GO:0005515//protein binding,-
57608,0,0,0,0,5,35,59,110,96,0,0,0,KIAA1462;KIAA1462,GO:0005911//cell-cell junction;GO:0005912//adherens junction,GO:0007155//cell adhesion,-,K11447//Transcriptional misregulation in cancer;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
57609,102,70,1,7,86,40,45,0,126,158,8,0,DIP2B;DIP2 disco-interacting protein 2 homolog B (Drosophila),GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0003824//catalytic activity;GO:0008134//transcription factor binding,-
57610,0,0,0,8,4,0,15,0,70,0,12,0,RANBP10;RAN binding protein 10,GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule;GO:0005829//cytosol,GO:0000226//microtubule cytoskeleton organization;GO:0032853//positive regulation of Ran GTPase activity,GO:0008536//Ran GTPase binding;GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0048487//beta-tubulin binding,-
57611,0,0,0,0,8,0,0,0,22,0,6,0,ISLR2;immunoglobulin superfamily containing leucine-rich repeat 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0045773//positive regulation of axon extension,-,K11447//Transcriptional misregulation in cancer;K06838//Axon guidance
57613,0,0,0,3,0,30,22,0,19,0,0,0,KIAA1467;KIAA1467,GO:0016021//integral component of membrane,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption
57614,7,10,1,26,136,15,16,0,26,0,0,103,KIAA1468;KIAA1468,-,-,-,-
57615,0,0,0,0,0,0,0,0,40,0,0,0,ZNF492;zinc finger protein 492,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
57616,33,0,0,9,0,11,0,0,2,0,0,0,TSHZ3;teashirt zinc finger homeobox 3,GO:0030426//growth cone;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0060993//kidney morphogenesis;GO:0072195//kidney smooth muscle cell differentiation;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0050881//musculoskeletal movement;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0006351//transcription, DNA-templated;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0001657//ureteric bud development;GO:0001656//metanephros development;GO:0072193//ureter smooth muscle cell differentiation;GO:0001701//in utero embryonic development;GO:0072105//ureteric peristalsis;GO:0050975//sensory perception of touch",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
57617,123,0,0,1,8,28,0,0,1,0,0,0,VPS18;vacuolar protein sorting 18 homolog (S. cerevisiae),GO:0005769//early endosome;GO:0005884//actin filament;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane,GO:0006886//intracellular protein transport;GO:0007032//endosome organization;GO:0007040//lysosome organization;GO:0016192//vesicle-mediated transport;GO:0046718//viral entry into host cell,GO:0003779//actin binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
57619,44,60,33,87,104,22,0,0,62,0,4,0,SHROOM3;shroom family member 3,GO:0005856//cytoskeleton;GO:0043296//apical junction complex;GO:0005912//adherens junction;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0001843//neural tube closure;GO:0045176//apical protein localization;GO:0002066//columnar/cuboidal epithelial cell development;GO:0043482//cellular pigment accumulation;GO:0007389//pattern specification process;GO:0008360//regulation of cell shape;GO:0030036//actin cytoskeleton organization;GO:0000902//cell morphogenesis,GO:0003779//actin binding,K05868//Progesterone-mediated oocyte maturation;Cell cycle;p53 signaling pathway;HTLV-I infection;Oocyte meiosis
57620,0,0,0,0,1,0,59,1,44,0,4,0,STIM2;stromal interaction molecule 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0070588//calcium ion transmembrane transport;GO:0032237//activation of store-operated calcium channel activity;GO:0006874//cellular calcium ion homeostasis;GO:0051928//positive regulation of calcium ion transport,GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0005509//calcium ion binding,K16059//Calcium signaling pathway
57621,52,0,0,0,26,0,0,0,7,38,0,0,ZBTB2;zinc finger and BTB domain containing 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57622,90,0,0,0,0,0,0,79,10,0,3,0,LRFN1;leucine rich repeat and fibronectin type III domain containing 1,GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,-,-,K07523//Axon guidance
57623,0,0,0,9,5,0,0,3,48,0,1,0,ZFAT;zinc finger and AT hook domain containing,GO:0005634//nucleus;GO:0005829//cytosol,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0002244//hematopoietic progenitor cell differentiation;GO:0060712//spongiotrophoblast layer development",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57624,0,0,0,0,0,14,32,0,45,0,0,0,NYAP2;neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2,-,GO:0048812//neuron projection morphogenesis;GO:0014065//phosphatidylinositol 3-kinase signaling,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
57626,98,0,0,0,19,13,0,0,0,124,19,0,KLHL1;kelch-like family member 1,GO:0005856//cytoskeleton;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0030425//dendrite,GO:0030036//actin cytoskeleton organization;GO:0021680//cerebellar Purkinje cell layer development;GO:0016358//dendrite development;GO:0007628//adult walking behavior,GO:0003779//actin binding,-
57628,0,0,0,0,0,0,26,0,16,0,7,109,DPP10;dipeptidyl-peptidase 10 (non-functional),GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0008239//dipeptidyl-peptidase activity,K01278//Protein digestion and absorption
5763,0,83,23,7,76,0,0,6,0,0,13,0,PTMS;parathymosin,GO:0005634//nucleus,GO:0006260//DNA replication;GO:0002376//immune system process,-,-
57630,170,30,2,61,141,45,0,0,31,0,0,0,SH3RF1;SH3 domain containing ring finger 1,GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0030027//lamellipodium,GO:0046328//regulation of JNK cascade;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,-
57631,0,0,1,0,16,5,0,0,37,0,10,0,LRCH2;leucine-rich repeats and calponin homology (CH) domain containing 2,-,-,-,K10130//NF-kappa B signaling pathway;p53 signaling pathway
57634,16,26,0,2,41,18,61,73,88,27,12,0,EP400;E1A binding protein p400,GO:0000812//Swr1 complex;GO:0005654//nucleoplasm;GO:0035267//NuA4 histone acetyltransferase complex;GO:0016607//nuclear speck,GO:0043967//histone H4 acetylation;GO:0043968//histone H2A acetylation;GO:0006325//chromatin organization,GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003677//DNA binding,-
57636,0,0,0,0,0,0,57,65,38,137,0,1,ARHGAP23;Rho GTPase activating protein 23,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K08878//Pathways in cancer;Chronic myeloid leukemia;K05732//Focal adhesion;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;K04450//Alcoholism;Influenza A;Dopaminergic synapse;Cocaine addiction;HTLV-I infection;Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction;K07526//Axon guidance
57639,0,0,0,0,0,0,37,0,33,0,0,0,CCDC146;coiled-coil domain containing 146,-,-,-,-
5764,42,0,0,0,0,7,0,0,0,0,0,0,PTN;pleiotrophin,GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum,GO:0043086//negative regulation of catalytic activity;GO:0051781//positive regulation of cell division;GO:0008284//positive regulation of cell proliferation;GO:0007399//nervous system development;GO:0030282//bone mineralization;GO:0007612//learning;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway,GO:0008083//growth factor activity;GO:0008201//heparin binding;GO:0004864//protein phosphatase inhibitor activity,-
57642,119,0,0,0,0,6,0,0,88,148,28,99,"COL20A1;collagen, type XX, alpha 1",GO:0005581//collagen trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0030198//extracellular matrix organization,-,K08133//Protein digestion and absorption
57643,47,1,0,0,17,0,0,9,91,0,6,0,"ZSWIM5;zinc finger, SWIM-type containing 5",GO:0005615//extracellular space,-,GO:0008270//zinc ion binding,-
57644,187,12,1,4,0,0,34,8,41,0,15,0,"MYH7B;myosin, heavy chain 7B, cardiac muscle, beta",GO:0032982//myosin filament;GO:0016020//membrane,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0003774//motor activity,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
57645,0,50,0,1,15,22,0,0,15,2,0,0,POGK;pogo transposable element with KRAB domain,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003677//DNA binding;GO:0005515//protein binding,-
57646,0,1,0,0,0,0,0,0,0,0,0,0,USP28;ubiquitin specific peptidase 28,GO:0005634//nucleus;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0016579//protein deubiquitination;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0006974//cellular response to DNA damage stimulus;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000077//DNA damage checkpoint;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0034644//cellular response to UV;GO:0008283//cell proliferation,GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,-
57647,92,0,34,0,0,18,30,0,25,97,13,0,DHX37;DEAH (Asp-Glu-Ala-His) box polypeptide 37,-,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0003676//nucleic acid binding;GO:0004386//helicase activity,-
57648,0,247,3,88,236,0,40,57,39,0,1,1,KIAA1522;KIAA1522,-,-,-,-
57649,49,0,0,34,141,49,22,0,124,0,14,0,PHF12;PHD finger protein 12,GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016580//Sin3 complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0001222//transcription corepressor binding;GO:0008270//zinc ion binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
57650,0,95,1,21,113,12,0,42,84,0,84,0,KIAA1524;KIAA1524,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:2000179//positive regulation of neural precursor cell proliferation;GO:0007283//spermatogenesis,GO:0005515//protein binding,-
57653,40,0,0,0,0,0,0,0,0,0,0,0,LOC100499484-C9ORF174;LOC100499484-C9orf174 readthrough,-,-,-,K12795//Plant-pathogen interaction;NOD-like receptor signaling pathway
57654,0,0,0,1,0,28,0,136,39,0,23,0,UVSSA;UV-stimulated scaffold protein A,GO:0005694//chromosome,GO:0009411//response to UV;GO:0016567//protein ubiquitination;GO:0006283//transcription-coupled nucleotide-excision repair,GO:0000993//RNA polymerase II core binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
57655,81,0,0,0,21,0,0,0,14,0,14,0,GRAMD1A;GRAM domain containing 1A,GO:0016021//integral component of membrane,-,-,-
57657,0,0,0,0,0,0,13,0,0,0,0,5,HCN3;hyperpolarization activated cyclic nucleotide-gated potassium channel 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0071320//cellular response to cAMP;GO:0035725//sodium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0042391//regulation of membrane potential,GO:0005248//voltage-gated sodium channel activity;GO:0030552//cAMP binding;GO:0005249//voltage-gated potassium channel activity,-
57658,104,34,1,7,32,17,1,31,13,0,2,0,CALCOCO1;calcium binding and coiled-coil domain 1,GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction",GO:0008013//beta-catenin binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0070016//armadillo repeat domain binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0008022//protein C-terminus binding;GO:0003712//transcription cofactor activity;GO:0005515//protein binding,K06102//Tight junction;K04559//Huntington's disease;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
57659,0,0,0,15,195,13,23,0,31,0,1,0,ZBTB4;zinc finger and BTB domain containing 4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0045892//negative regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0008327//methyl-CpG binding;GO:0010428//methyl-CpNpG binding,-
57661,75,0,0,0,0,8,0,53,90,0,1,0,PHRF1;PHD and ring finger domains 1,GO:0016020//membrane,GO:0006366//transcription from RNA polymerase II promoter;GO:0006397//mRNA processing,GO:0008270//zinc ion binding;GO:0070063//RNA polymerase binding;GO:0019904//protein domain specific binding,-
57662,0,0,0,0,0,0,30,0,0,1,12,0,"CAMSAP3;calmodulin regulated spectrin-associated protein family, member 3",GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005915//zonula adherens,GO:0045218//zonula adherens maintenance;GO:0010923//negative regulation of phosphatase activity;GO:0034453//microtubule anchoring;GO:0033043//regulation of organelle organization;GO:0000226//microtubule cytoskeleton organization;GO:0090136//epithelial cell-cell adhesion;GO:0070507//regulation of microtubule cytoskeleton organization,GO:0051011//microtubule minus-end binding,-
57663,0,0,0,0,0,0,28,0,37,0,1,0,USP29;ubiquitin specific peptidase 29,-,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004221//ubiquitin thiolesterase activity;GO:0008234//cysteine-type peptidase activity,-
57664,1,0,0,0,0,0,0,0,42,237,0,0,"PLEKHA4;pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4",GO:0016020//membrane;GO:0005737//cytoplasm,-,GO:0005545//1-phosphatidylinositol binding,K03426//Peroxisome;Nicotinate and nicotinamide metabolism
57665,2,0,0,0,13,0,0,60,28,0,0,0,RDH14;retinol dehydrogenase 14 (all-trans/9-cis/11-cis),GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum,GO:0001649//osteoblast differentiation;GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
57666,0,0,0,0,18,5,31,35,36,0,37,1,FBRSL1;fibrosin-like 1,-,-,GO:0044822//poly(A) RNA binding,-
57669,33,20,1,57,97,15,1,87,54,0,9,1,EPB41L5;erythrocyte membrane protein band 4.1 like 5,GO:0019898//extrinsic component of membrane;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0032587//ruffle membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane,"GO:0001701//in utero embryonic development;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0007509//mesoderm migration involved in gastrulation;GO:0032525//somite rostral/caudal axis specification;GO:0007398//ectoderm development;GO:0001837//epithelial to mesenchymal transition;GO:0006931//substrate-dependent cell migration, cell attachment to substrate;GO:0010608//posttranscriptional regulation of gene expression;GO:0051894//positive regulation of focal adhesion assembly;GO:0003383//apical constriction;GO:0032092//positive regulation of protein binding;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0007492//endoderm development;GO:0048319//axial mesoderm morphogenesis;GO:0048339//paraxial mesoderm development;GO:0032091//negative regulation of protein binding;GO:0048617//embryonic foregut morphogenesis;GO:0031032//actomyosin structure organization;GO:0070201//regulation of establishment of protein localization;GO:0022408//negative regulation of cell-cell adhesion;GO:0009826//unidimensional cell growth;GO:0010634//positive regulation of epithelial cell migration;GO:0070986//left/right axis specification;GO:0001839//neural plate morphogenesis",GO:0008092//cytoskeletal protein binding;GO:0019904//protein domain specific binding,K06107//Tight junction
57670,45,0,0,0,0,27,60,0,59,0,0,0,KIAA1549;KIAA1549,GO:0016021//integral component of membrane,-,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
57673,0,0,0,6,12,38,0,0,40,137,0,237,BEND3;BEN domain containing 3,-,-,-,-
57674,326,142,0,98,245,84,61,134,159,204,164,342,RNF213;ring finger protein 213,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0051865//protein autoubiquitination;GO:0006200//ATP catabolic process;GO:0016567//protein ubiquitination,GO:0016887//ATPase activity;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K04006//Complement and coagulation cascades;Viral myocarditis;Hematopoietic cell lineage;K01557//Tyrosine metabolism;Metabolic pathways
57677,0,0,0,21,16,0,23,42,39,26,0,0,ZFP14;ZFP14 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
57678,208,0,0,0,25,33,4,0,57,0,0,42,"GPAM;glycerol-3-phosphate acyltransferase, mitochondrial",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane,GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0006654//phosphatidic acid biosynthetic process;GO:0055089//fatty acid homeostasis;GO:0050707//regulation of cytokine secretion;GO:0055091//phospholipid homeostasis;GO:0042104//positive regulation of activated T cell proliferation;GO:0006637//acyl-CoA metabolic process;GO:0006644//phospholipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0040018//positive regulation of multicellular organism growth;GO:0051607//defense response to virus;GO:0070970//interleukin-2 secretion;GO:0006631//fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0009749//response to glucose;GO:0046474//glycerophospholipid biosynthetic process,GO:0004366//glycerol-3-phosphate O-acyltransferase activity,K00629//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism
57679,0,1,0,9,29,16,0,41,102,0,0,0,ALS2;amyotrophic lateral sclerosis 2 (juvenile),GO:0005829//cytosol;GO:0001726//ruffle;GO:0005769//early endosome;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0030027//lamellipodium;GO:0043234//protein complex;GO:0005813//centrosome;GO:0031982//vesicle;GO:0030426//growth cone;GO:0043197//dendritic spine,"GO:0001881//receptor recycling;GO:0016050//vesicle organization;GO:0008104//protein localization;GO:0032851//positive regulation of Rab GTPase activity;GO:0032855//positive regulation of Rac GTPase activity;GO:0035022//positive regulation of Rac protein signal transduction;GO:0035249//synaptic transmission, glutamatergic;GO:0048812//neuron projection morphogenesis;GO:0007528//neuromuscular junction development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0007626//locomotory behavior;GO:0008219//cell death;GO:0016197//endosomal transport;GO:0006979//response to oxidative stress;GO:0045860//positive regulation of protein kinase activity;GO:0051036//regulation of endosome size;GO:0007032//endosome organization;GO:0001662//behavioral fear response;GO:0032853//positive regulation of Ran GTPase activity",GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005087//Ran guanyl-nucleotide exchange factor activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0017137//Rab GTPase binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0043539//protein serine/threonine kinase activator activity,K04575//Amyotrophic lateral sclerosis (ALS)
5768,0,0,0,0,0,0,0,0,18,0,0,0,QSOX1;quiescin Q6 sulfhydryl oxidase 1,GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0055114//oxidation-reduction process;GO:0006457//protein folding;GO:0045454//cell redox homeostasis,GO:0016971//flavin-linked sulfhydryl oxidase activity;GO:0003756//protein disulfide isomerase activity,-
57680,1,1,0,14,44,1,0,24,94,134,0,0,CHD8;chromodomain helicase DNA binding protein 8,GO:0005730//nucleolus;GO:0071339//MLL1 complex;GO:0043234//protein complex;GO:0005634//nucleus,"GO:2000270//negative regulation of fibroblast apoptotic process;GO:0032508//DNA duplex unwinding;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060070//canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0030178//negative regulation of Wnt signaling pathway;GO:0043044//ATP-dependent chromatin remodeling;GO:0006200//ATP catabolic process;GO:0001701//in utero embryonic development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003678//DNA helicase activity;GO:0035064//methylated histone binding;GO:0003677//DNA binding;GO:0002039//p53 binding;GO:0008013//beta-catenin binding;GO:0005524//ATP binding;GO:0070016//armadillo repeat domain binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0008094//DNA-dependent ATPase activity,K04494//Wnt signaling pathway
57683,0,69,0,13,79,0,0,0,205,0,0,0,"ZDBF2;zinc finger, DBF-type containing 2",-,-,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K03257//RNA transport
57684,0,0,0,9,15,0,62,0,8,0,1,0,ZBTB26;zinc finger and BTB domain containing 26,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
57685,0,0,0,0,3,0,20,0,49,218,0,1,CACHD1;cache domain containing 1,GO:0016021//integral component of membrane,GO:0006816//calcium ion transport,-,K04859//MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction;K04858//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway;Dilated cardiomyopathy;Cardiac muscle contraction
57687,0,0,0,0,0,21,13,0,22,0,0,0,VAT1L;vesicle amine transport 1-like,-,GO:0055114//oxidation-reduction process,GO:0008270//zinc ion binding;GO:0016491//oxidoreductase activity,K00344//Fatty acid metabolism;Chloroalkane and chloroalkene degradation;Naphthalene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments
57688,79,0,1,0,0,5,52,73,39,0,0,0,"ZSWIM6;zinc finger, SWIM-type containing 6",-,GO:2001222//regulation of neuron migration;GO:0048812//neuron projection morphogenesis,GO:0008270//zinc ion binding,-
57689,0,0,0,0,0,43,0,0,27,52,0,0,LRRC4C;leucine rich repeat containing 4C,GO:0030054//cell junction;GO:0005615//extracellular space;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0050770//regulation of axonogenesis,GO:0005515//protein binding,K07523//Axon guidance
57690,0,0,1,37,38,0,44,0,30,0,33,1,TNRC6C;trinucleotide repeat containing 6C,GO:0005829//cytosol,"GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060964//regulation of gene silencing by miRNA;GO:0007219//Notch signaling pathway;GO:0035162//embryonic hemopoiesis;GO:0001706//endoderm formation;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0010467//gene expression;GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K06237//ECM-receptor interaction;Pathways in cancer;Focal adhesion;Protein digestion and absorption;Small cell lung cancer;Amoebiasis
57691,0,0,0,9,2,8,21,0,0,0,0,0,KIAA1586;KIAA1586,-,-,GO:0003676//nucleic acid binding,-
57692,0,0,0,4,0,0,14,0,0,0,0,0,"MAGEE1;melanoma antigen family E, 1",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0016010//dystrophin-associated glycoprotein complex;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
57693,79,0,0,0,1,8,0,1,14,76,10,0,ZNF317;zinc finger protein 317,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
57695,99,14,0,8,34,22,0,24,44,0,1,0,USP37;ubiquitin specific peptidase 37,GO:0005634//nucleus,GO:0007067//mitotic nuclear division;GO:0035871//protein K11-linked deubiquitination;GO:0016579//protein deubiquitination;GO:0000082//G1/S transition of mitotic cell cycle;GO:0071108//protein K48-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004843//ubiquitin-specific protease activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity,-
57696,0,0,0,0,16,13,0,0,31,0,2,0,DDX55;DEAD (Asp-Glu-Ala-Asp) box polypeptide 55,GO:0016020//membrane,GO:0006200//ATP catabolic process,GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
57697,76,0,0,0,0,18,0,1,76,0,0,70,"FANCM;Fanconi anemia, complementation group M",GO:0043240//Fanconi anaemia nuclear complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0071821//FANCM-MHF complex;GO:0005634//nucleus,GO:0031297//replication fork processing;GO:0000712//resolution of meiotic recombination intermediates;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair,GO:0004518//nuclease activity;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0005515//protein binding,K10896//Fanconi anemia pathway
57698,22,1,1,41,122,27,32,0,37,0,1,0,KIAA1598;KIAA1598,GO:0044295//axonal growth cone,GO:2001222//regulation of neuron migration;GO:0007411//axon guidance;GO:2000114//regulation of establishment of cell polarity,GO:0019900//kinase binding,K06267//ECM-receptor interaction;K09288//Thyroid cancer;Pathways in cancer;K11423//Lysine degradation;K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
57699,0,0,0,0,0,0,0,17,41,0,31,0,CPNE5;copine V,GO:0043025//neuronal cell body;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome,-,-,K06491//Prion diseases;Cell adhesion molecules (CAMs);K02677//Leishmaniasis;Pathogenic Escherichia coli infection;Glioma;Gastric acid secretion;VEGF signaling pathway;Focal adhesion;Long-term depression;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Retrograde endocannabinoid signaling;Calcium signaling pathway;Leukocyte transendothelial migration;MAPK signaling pathway;Morphine addiction;ErbB signaling pathway;Dopaminergic synapse;Gap junction;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;NF-kappa B signaling pathway;Serotonergic synapse;Influenza A;Non-small cell lung cancer;Vibrio cholerae infection;Melanogenesis;Tight junction;GABAergic synapse;Fc epsilon RI signaling pathway;Cholinergic synapse;Salivary secretion;B cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Amphetamine addiction;Glutamatergic synapse;Vascular smooth muscle contraction;Wnt signaling pathway;Phototransduction - fly;Amoebiasis;MAPK signaling pathway - yeast;Phosphatidylinositol signaling system;Pancreatic secretion;African trypanosomiasis;Aldosterone-regulated sodium reabsorption;Long-term potentiation;Carbohydrate digestion and absorption;K15290//Synaptic vesicle cycle
577,119,0,0,0,0,18,21,2,60,0,0,0,BAI3;brain-specific angiogenesis inhibitor 3,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0016525//negative regulation of angiogenesis;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity,-
5770,0,0,3,6,35,0,15,46,21,0,12,1,"PTPN1;protein tyrosine phosphatase, non-receptor type 1",GO:0097443//sorting endosome;GO:0005789//endoplasmic reticulum membrane;GO:0031410//cytoplasmic vesicle;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005769//early endosome;GO:0005886//plasma membrane,GO:1902202//regulation of hepatocyte growth factor receptor signaling pathway;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway;GO:1990264//peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity;GO:0030100//regulation of endocytosis;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0030168//platelet activation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0035791//platelet-derived growth factor receptor-beta signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0007596//blood coagulation;GO:0009966//regulation of signal transduction;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0030971//receptor tyrosine kinase binding;GO:0005158//insulin receptor binding;GO:0019899//enzyme binding;GO:0046875//ephrin receptor binding,K05696//Insulin signaling pathway;Adherens junction
57700,56,0,0,27,45,0,0,0,20,0,1,0,"FAM160B1;family with sequence similarity 160, member B1",-,-,-,-
57701,0,0,0,0,7,11,0,0,4,0,0,0,NCKAP5L;NCK-associated protein 5-like,-,-,-,K13911//Salivary secretion;K06237//ECM-receptor interaction;Pathways in cancer;Focal adhesion;Protein digestion and absorption;Small cell lung cancer;Amoebiasis
57703,114,0,0,14,29,14,33,0,18,1,5,0,CWC22;CWC22 spliceosome-associated protein,GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0000398//mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0005515//protein binding,-
57704,69,325,214,386,533,25,19,2,60,163,324,0,"GBA2;glucosidase, beta (bile acid) 2",GO:0005790//smooth endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0021954//central nervous system neuron development;GO:0008206//bile acid metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0006680//glucosylceramide catabolic process;GO:0006665//sphingolipid metabolic process;GO:0016139//glycoside catabolic process,GO:0008422//beta-glucosidase activity;GO:0004348//glucosylceramidase activity,-
57705,241,0,0,0,0,30,65,8,75,0,6,0,WDFY4;WDFY family member 4,GO:0016021//integral component of membrane,-,-,-
57706,11,0,0,11,0,44,17,0,75,88,11,0,DENND1A;DENN/MADD domain containing 1A,GO:0030136//clathrin-coated vesicle;GO:0030054//cell junction;GO:0030425//dendrite;GO:0042734//presynaptic membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0043025//neuronal cell body,GO:0006897//endocytosis;GO:0032851//positive regulation of Rab GTPase activity;GO:0048488//synaptic vesicle endocytosis;GO:0015031//protein transport,GO:0017124//SH3 domain binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome;K05753//Bacterial invasion of epithelial cells;Salmonella infection;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Adherens junction;Shigellosis
57707,20,1,0,8,26,17,50,17,27,0,9,214,TLDC1;TBC/LysM-associated domain containing 1,GO:0005765//lysosomal membrane,-,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
57708,0,0,0,48,130,0,19,0,70,17,0,0,"MIER1;mesoderm induction early response 1, transcriptional regulator",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus,"GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031937//positive regulation of chromatin silencing;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity,-
57709,1,0,0,0,0,10,104,21,48,0,17,0,"SLC7A14;solute carrier family 7, member 14",GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0010923//negative regulation of phosphatase activity;GO:0003333//amino acid transmembrane transport,GO:0015171//amino acid transmembrane transporter activity,-
5771,0,0,0,6,5,3,21,0,16,0,0,0,"PTPN2;protein tyrosine phosphatase, non-receptor type 2",GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0030183//B cell differentiation;GO:1902212//negative regulation of prolactin signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0050922//negative regulation of chemotaxis;GO:0045722//positive regulation of gluconeogenesis;GO:0019221//cytokine-mediated signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0030218//erythrocyte differentiation;GO:0010888//negative regulation of lipid storage;GO:0030217//T cell differentiation;GO:1902206//negative regulation of interleukin-2-mediated signaling pathway;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:2000587//negative regulation of platelet-derived growth factor receptor-beta signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0070104//negative regulation of interleukin-6-mediated signaling pathway;GO:1902215//negative regulation of interleukin-4-mediated signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:1902233//negative regulation of positive thymic T cell selection;GO:0042512//negative regulation of tyrosine phosphorylation of Stat1 protein;GO:0042524//negative regulation of tyrosine phosphorylation of Stat5 protein;GO:0045650//negative regulation of macrophage differentiation;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:1902227//negative regulation of macrophage colony-stimulating factor signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0042518//negative regulation of tyrosine phosphorylation of Stat3 protein;GO:1902202//regulation of hepatocyte growth factor receptor signaling pathway;GO:0042593//glucose homeostasis;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0008285//negative regulation of cell proliferation;GO:0042527//negative regulation of tyrosine phosphorylation of Stat6 protein;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway,GO:0019901//protein kinase binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019905//syntaxin binding;GO:0030971//receptor tyrosine kinase binding,-
57710,101,0,0,6,0,12,20,41,20,0,18,0,KIAA1614;KIAA1614,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
57711,0,0,0,3,0,8,16,0,16,167,10,0,ZNF529;zinc finger protein 529,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
57713,0,0,1,30,49,32,30,56,33,0,0,0,SFMBT2;Scm-like with four mbt domains 2,GO:0005634//nucleus,"GO:0010629//negative regulation of gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0042393//histone binding,-
57715,0,106,1,20,100,10,0,0,36,0,40,0,"SEMA4G;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007399//nervous system development,GO:0004872//receptor activity,K06521//Axon guidance
57716,0,0,1,4,0,0,6,39,15,0,14,0,PRX;periaxin,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0008366//axon ensheathment,GO:0005515//protein binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
57717,0,0,0,0,0,0,0,0,38,0,0,0,PCDHB16;protocadherin beta 16,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007416//synapse assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission,GO:0005509//calcium ion binding,-
57718,44,0,0,0,0,16,19,0,77,0,0,0,"PPP4R4;protein phosphatase 4, regulatory subunit 4",GO:0005737//cytoplasm;GO:0008287//protein serine/threonine phosphatase complex,GO:0032515//negative regulation of phosphoprotein phosphatase activity;GO:0080163//regulation of protein serine/threonine phosphatase activity,GO:0019888//protein phosphatase regulator activity;GO:0005515//protein binding,-
57719,0,0,30,8,10,5,0,1,9,0,22,162,ANO8;anoctamin 8,GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006821//chloride transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport,GO:0005229//intracellular calcium activated chloride channel activity,K03018//Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism;Cytosolic DNA-sensing pathway;Metabolic pathways
57720,177,71,0,21,9,30,21,0,39,25,7,0,GPR107;G protein-coupled receptor 107,GO:0016021//integral component of membrane,-,-,-
57721,0,0,0,26,75,0,0,0,17,0,0,0,METTL14;methyltransferase like 14,GO:0005634//nucleus;GO:0036396//MIS complex,GO:0061157//mRNA destabilization;GO:0019827//stem cell maintenance;GO:0080009//mRNA methylation,GO:0016422//mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity;GO:0003723//RNA binding,-
57722,131,0,0,0,0,12,17,0,33,0,5,0,"IGDCC4;immunoglobulin superfamily, DCC subclass, member 4",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K06765//Axon guidance;Pathways in cancer;Colorectal cancer;K06766//Cell adhesion molecules (CAMs)
57724,0,2,0,16,92,87,33,1,151,105,0,277,EPG5;ectopic P-granules autophagy protein 5 homolog (C. elegans),-,GO:0006914//autophagy;GO:0032456//endocytic recycling,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
57727,54,0,0,23,66,0,1,0,29,0,8,0,NCOA5;nuclear receptor coactivator 5,GO:0005615//extracellular space;GO:0015629//actin cytoskeleton;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K09186//Lysine degradation;Transcriptional misregulation in cancer
57728,62,0,0,2,0,24,5,0,46,0,0,0,WDR19;WD repeat domain 19,GO:0031514//motile cilium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030991//intraciliary transport particle A;GO:0031513//nonmotile primary cilium;GO:0032391//photoreceptor connecting cilium,GO:0042384//cilium assembly;GO:0035721//intraciliary retrograde transport;GO:0031076//embryonic camera-type eye development;GO:0061055//myotome development;GO:0042471//ear morphogenesis;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0055123//digestive system development;GO:0050877//neurological system process;GO:0001701//in utero embryonic development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0030326//embryonic limb morphogenesis,-,K03364//Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;Cell cycle
57730,1,0,0,0,0,24,41,50,17,0,9,65,ANKRD36B;ankyrin repeat domain 36B,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Gastric acid secretion;Calcium signaling pathway;K11447//Transcriptional misregulation in cancer
57731,202,0,0,0,7,12,77,28,70,98,3,0,"SPTBN4;spectrin, beta, non-erythrocytic 4",GO:0016605//PML body;GO:0043194//axon initial segment;GO:0005829//cytosol;GO:0070852//cell body fiber;GO:0005912//adherens junction;GO:0016363//nuclear matrix;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0008091//spectrin;GO:0016020//membrane;GO:0033270//paranode region of axon;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0033268//node of Ranvier;GO:0043203//axon hillock,GO:0033135//regulation of peptidyl-serine phosphorylation;GO:0010459//negative regulation of heart rate;GO:0016192//vesicle-mediated transport;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007605//sensory perception of sound;GO:0045162//clustering of voltage-gated sodium channels;GO:0007409//axonogenesis;GO:0019226//transmission of nerve impulse;GO:0051693//actin filament capping;GO:0002028//regulation of sodium ion transport;GO:0021952//central nervous system projection neuron axonogenesis;GO:0007411//axon guidance;GO:0007628//adult walking behavior;GO:0040018//positive regulation of multicellular organism growth;GO:0061337//cardiac conduction;GO:0009566//fertilization;GO:0090002//establishment of protein localization to plasma membrane,GO:0030507//spectrin binding;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0005515//protein binding;GO:0030506//ankyrin binding;GO:0005543//phospholipid binding;GO:0019902//phosphatase binding,K06115//Tight junction
57732,0,0,0,0,7,0,40,0,0,86,6,0,"ZFYVE28;zinc finger, FYVE domain containing 28",GO:0031901//early endosome membrane;GO:0005829//cytosol,GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity,GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K12182//Phagosome;Endocytosis
57733,0,0,0,0,0,0,0,0,50,0,0,0,"GBA3;glucosidase, beta, acid 3",GO:0005829//cytosol,GO:0016139//glycoside catabolic process;GO:0005975//carbohydrate metabolic process;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0046477//glycosylceramide catabolic process;GO:0006687//glycosphingolipid metabolic process,GO:0017042//glycosylceramidase activity;GO:0008422//beta-glucosidase activity;GO:0004565//beta-galactosidase activity,K05350//Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Cyanoamino acid metabolism;Phenylpropanoid biosynthesis;Metabolic pathways
5774,0,43,1,18,70,57,0,1,36,126,6,0,"PTPN3;protein tyrosine phosphatase, non-receptor type 3",GO:0009898//cytoplasmic side of plasma membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0045930//negative regulation of mitotic cell cycle;GO:0051045//negative regulation of membrane protein ectodomain proteolysis,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0017080//sodium channel regulator activity;GO:0051117//ATPase binding;GO:0008092//cytoskeletal protein binding;GO:0001784//phosphotyrosine binding,-
5775,0,36,1,2,29,9,34,79,62,0,0,0,"PTPN4;protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0008092//cytoskeletal protein binding;GO:0005515//protein binding;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity,-
57758,45,0,0,0,0,11,94,0,56,0,0,0,"SCUBE2;signal peptide, CUB domain, EGF-like 2",GO:0005576//extracellular region,-,GO:0005509//calcium ion binding,-
57761,0,31,0,0,0,0,0,0,14,0,11,0,TRIB3;tribbles pseudokinase 3,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0034976//response to endoplasmic reticulum stress;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010827//regulation of glucose transport;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0043405//regulation of MAP kinase activity;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0032869//cellular response to insulin stimulus;GO:0032092//positive regulation of protein binding;GO:0006351//transcription, DNA-templated",GO:0004860//protein kinase inhibitor activity;GO:0005515//protein binding;GO:0055106//ubiquitin-protein transferase regulator activity;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0016301//kinase activity;GO:0003714//transcription corepressor activity;GO:0005524//ATP binding,-
57763,0,0,0,0,0,0,0,0,4,0,0,0,"ANKRA2;ankyrin repeat, family A (RFXANK-like), 2",GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0016020//membrane;GO:0005829//cytosol,-,GO:0030169//low-density lipoprotein particle binding;GO:0042826//histone deacetylase binding,K08062//Antigen processing and presentation;Tuberculosis;Primary immunodeficiency
5777,0,0,1,4,6,0,73,30,20,67,29,0,"PTPN6;protein tyrosine phosphatase, non-receptor type 6",GO:0005737//cytoplasm;GO:0042105//alpha-beta T cell receptor complex;GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0035855//megakaryocyte development;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0031295//T cell costimulation;GO:0050853//B cell receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0043407//negative regulation of MAP kinase activity;GO:0006915//apoptotic process;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0030154//cell differentiation;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0002924//negative regulation of humoral immune response mediated by circulating immunoglobulin;GO:0050900//leukocyte migration;GO:0008283//cell proliferation;GO:0045577//regulation of B cell differentiation;GO:0070527//platelet aggregation;GO:0008285//negative regulation of cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0042267//natural killer cell mediated cytotoxicity;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0042130//negative regulation of T cell proliferation;GO:0007596//blood coagulation;GO:0006470//protein dephosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0060333//interferon-gamma-mediated signaling pathway;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0033277//abortive mitotic cell cycle;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0030220//platelet formation,GO:0001784//phosphotyrosine binding;GO:0042169//SH2 domain binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding;GO:0017124//SH3 domain binding,K05697//Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Leishmaniasis;Jak-STAT signaling pathway;Adherens junction;B cell receptor signaling pathway
5778,0,0,0,0,0,0,0,138,0,126,0,0,"PTPN7;protein tyrosine phosphatase, non-receptor type 7",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0009898//cytoplasmic side of plasma membrane;GO:0005829//cytosol,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding,K04458//MAPK signaling pathway
57786,80,0,1,15,41,0,0,0,28,0,11,0,RBAK;RB-associated KRAB zinc finger,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,-
57787,42,0,0,15,34,0,29,1,45,98,6,0,MARK4;MAP/microtubule affinity-regulating kinase 4,GO:0005813//centrosome;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0043005//neuron projection,GO:0001578//microtubule bundle formation;GO:0043068//positive regulation of programmed cell death;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0000226//microtubule cytoskeleton organization,GO:0043015//gamma-tubulin binding;GO:0005524//ATP binding;GO:0043130//ubiquitin binding;GO:0050321//tau-protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0008017//microtubule binding;GO:0005515//protein binding,-
57794,0,0,0,0,7,15,0,0,19,0,0,0,SUGP1;SURP and G patch domain containing 1,GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex,"GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
57795,0,0,0,0,19,22,3,0,5,0,0,0,BRINP2;bone morphogenetic protein/retinoic acid inducible neural-specific 2,GO:0005576//extracellular region,GO:0071300//cellular response to retinoic acid;GO:0045930//negative regulation of mitotic cell cycle;GO:0045666//positive regulation of neuron differentiation;GO:0007050//cell cycle arrest,-,-
57798,0,49,0,31,33,0,1,68,15,0,0,476,GATAD1;GATA zinc finger domain containing 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
57799,0,0,0,0,1,11,26,0,0,0,10,0,"RAB40C;RAB40C, member RAS oncogene family",GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane,GO:0015031//protein transport;GO:0016567//protein ubiquitination;GO:0007264//small GTPase mediated signal transduction,GO:0019003//GDP binding;GO:0005525//GTP binding,-
578,54,0,0,0,0,0,0,1,24,0,5,0,BAK1;BCL2-antagonist/killer 1,GO:0031307//integral component of mitochondrial outer membrane;GO:0005829//cytosol;GO:0046930//pore complex;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane,GO:0045862//positive regulation of proteolysis;GO:0051881//regulation of mitochondrial membrane potential;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0097190//apoptotic signaling pathway;GO:0043496//regulation of protein homodimerization activity;GO:0035108//limb morphogenesis;GO:0007568//aging;GO:0031018//endocrine pancreas development;GO:0009620//response to fungus;GO:0014070//response to organic cyclic compound;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0008283//cell proliferation;GO:0002352//B cell negative selection;GO:0042542//response to hydrogen peroxide;GO:0051726//regulation of cell cycle;GO:0007420//brain development;GO:0008285//negative regulation of cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0010629//negative regulation of gene expression;GO:0002262//myeloid cell homeostasis;GO:1902262//apoptotic process involved in patterning of blood vessels;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0006915//apoptotic process;GO:0001782//B cell homeostasis;GO:0001783//B cell apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0001836//release of cytochrome c from mitochondria;GO:0008053//mitochondrial fusion;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0043497//regulation of protein heterodimerization activity;GO:0046902//regulation of mitochondrial membrane permeability;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0010046//response to mycotoxin;GO:0070242//thymocyte apoptotic process;GO:0010332//response to gamma radiation;GO:0034644//cellular response to UV;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0044346//fibroblast apoptotic process;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0010225//response to UV-C;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045471//response to ethanol;GO:0031100//organ regeneration;GO:0060068//vagina development;GO:0042493//response to drug;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0001974//blood vessel remodeling,GO:0042802//identical protein binding;GO:0051087//chaperone binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0031072//heat shock protein binding;GO:0051400//BH domain binding,K14021//Protein processing in endoplasmic reticulum
5780,0,37,0,8,33,0,1,0,11,0,0,0,"PTPN9;protein tyrosine phosphatase, non-receptor type 9",GO:0005737//cytoplasm,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity,-
57804,0,28,0,0,16,0,19,50,27,0,39,0,"POLD4;polymerase (DNA-directed), delta 4, accessory subunit",GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair;GO:0006284//base-excision repair",GO:0003887//DNA-directed DNA polymerase activity;GO:0005515//protein binding,K03505//Purine metabolism;DNA replication;Metabolic pathways;Homologous recombination;Base excision repair;Pyrimidine metabolism;Mismatch repair;HTLV-I infection;Nucleotide excision repair
57805,0,136,156,49,139,1,20,406,202,0,180,316,CCAR2;cell cycle and apoptosis regulator 2,GO:0044609//DBIRD complex;GO:0005681//spliceosomal complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,"GO:0042752//regulation of circadian rhythm;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0043086//negative regulation of catalytic activity;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0009411//response to UV;GO:0043065//positive regulation of apoptotic process;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:2000003//positive regulation of DNA damage checkpoint;GO:0031647//regulation of protein stability;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0006974//cellular response to DNA damage stimulus;GO:0007049//cell cycle",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity;GO:0000993//RNA polymerase II core binding,-
5781,54,60,1,78,253,1,0,0,76,0,0,0,"PTPN11;protein tyrosine phosphatase, non-receptor type 11",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex,GO:0007420//brain development;GO:0038127//ERBB signaling pathway;GO:0035265//organ growth;GO:0048015//phosphatidylinositol-mediated signaling;GO:0000077//DNA damage checkpoint;GO:0048609//multicellular organismal reproductive process;GO:0045087//innate immune response;GO:0042593//glucose homeostasis;GO:0048013//ephrin receptor signaling pathway;GO:0007507//heart development;GO:0007596//blood coagulation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0008286//insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0040014//regulation of multicellular organism growth;GO:0042445//hormone metabolic process;GO:0030220//platelet formation;GO:0048839//inner ear development;GO:0009755//hormone-mediated signaling pathway;GO:0033277//abortive mitotic cell cycle;GO:0051463//negative regulation of cortisol secretion;GO:0046887//positive regulation of hormone secretion;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0000187//activation of MAPK activity;GO:0036302//atrioventricular canal development;GO:0007411//axon guidance;GO:2001275//positive regulation of glucose import in response to insulin stimulus;GO:0060325//face morphogenesis;GO:0035855//megakaryocyte development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0048806//genitalia development;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0046825//regulation of protein export from nucleus;GO:0019221//cytokine-mediated signaling pathway;GO:0006641//triglyceride metabolic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0060125//negative regulation of growth hormone secretion;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007229//integrin-mediated signaling pathway,GO:0004721//phosphoprotein phosphatase activity;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity;GO:0051428//peptide hormone receptor binding;GO:0004725//protein tyrosine phosphatase activity;GO:0043274//phospholipase binding;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding;GO:0005158//insulin receptor binding;GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding;GO:0043560//insulin receptor substrate binding;GO:0031748//D1 dopamine receptor binding,K07293//Leukocyte transendothelial migration;Jak-STAT signaling pathway;Renal cell carcinoma;Epithelial cell signaling in Helicobacter pylori infection;MAPK signaling pathway - fly;Adipocytokine signaling pathway;Natural killer cell mediated cytotoxicity;Herpes simplex infection;Neurotrophin signaling pathway;Chronic myeloid leukemia
57817,0,0,0,0,0,0,0,0,7,0,0,0,HAMP;hepcidin antimicrobial peptide,GO:0045179//apical cortex;GO:0005576//extracellular region,GO:0042742//defense response to bacterium;GO:0031640//killing of cells of other organism;GO:0006879//cellular iron ion homeostasis;GO:0050832//defense response to fungus;GO:0006955//immune response,GO:0005179//hormone activity,-
57818,0,0,0,0,0,16,0,34,26,0,0,0,"G6PC2;glucose-6-phosphatase, catalytic, 2",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006094//gluconeogenesis;GO:0050796//regulation of insulin secretion;GO:0016311//dephosphorylation;GO:0015758//glucose transport;GO:0055085//transmembrane transport;GO:0042593//glucose homeostasis;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process,GO:0004346//glucose-6-phosphatase activity,K01084//Galactose metabolism;Insulin signaling pathway;Metabolic pathways;Adipocytokine signaling pathway;Carbohydrate digestion and absorption;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis
57819,0,0,0,0,0,0,0,1,0,0,0,0,"LSM2;LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)",GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005829//cytosol,"GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0017070//U6 snRNA binding,K12621//Spliceosome;RNA degradation
5782,0,0,0,0,25,0,49,0,19,0,0,112,"PTPN12;protein tyrosine phosphatase, non-receptor type 12",GO:0002102//podosome;GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030054//cell junction,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0042246//tissue regeneration,GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0004726//non-membrane spanning protein tyrosine phosphatase activity,-
57820,0,0,0,0,16,0,0,0,0,0,0,0,"CCNB1IP1;cyclin B1 interacting protein 1, E3 ubiquitin protein ligase",GO:0000795//synaptonemal complex,GO:0016567//protein ubiquitination;GO:0051026//chiasma assembly;GO:0007131//reciprocal meiotic recombination;GO:0001825//blastocyst formation;GO:0007286//spermatid development,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,-
57822,0,0,34,0,0,24,0,0,53,0,0,150,GRHL3;grainyhead-like 3 (Drosophila),GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0008544//epidermis development;GO:0042060//wound healing;GO:0001736//establishment of planar polarity;GO:0007389//pattern specification process;GO:0032956//regulation of actin cytoskeleton organization;GO:0007417//central nervous system development;GO:0032321//positive regulation of Rho GTPase activity;GO:0061029//eyelid development in camera-type eye;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0007398//ectoderm development;GO:0090103//cochlea morphogenesis,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0005515//protein binding,-
57823,0,0,0,0,0,0,0,0,13,0,0,0,SLAMF7;SLAM family member 7,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,GO:0032814//regulation of natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity;GO:0007155//cell adhesion;GO:0030101//natural killer cell activation,GO:0004872//receptor activity,-
57824,0,0,0,0,0,0,0,0,2,0,0,0,HMHB1;histocompatibility (minor) HB-1,-,GO:0002376//immune system process,-,-
57826,0,17,0,7,21,10,21,0,66,0,0,0,"RAP2C;RAP2C, member of RAS oncogene family",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0055038//recycling endosome membrane;GO:0005737//cytoplasm,GO:0031954//positive regulation of protein autophosphorylation;GO:0006184//GTP catabolic process;GO:0032486//Rap protein signal transduction;GO:0030336//negative regulation of cell migration;GO:0061097//regulation of protein tyrosine kinase activity;GO:2001141//regulation of RNA biosynthetic process,GO:0005525//GTP binding;GO:0003713//transcription coactivator activity;GO:0019003//GDP binding,-
57828,21,0,0,0,0,26,0,0,38,0,9,0,CATSPERG;catsper channel auxiliary subunit gamma,GO:0036128//CatSper complex;GO:0005886//plasma membrane;GO:0097228//sperm principal piece,GO:0030154//cell differentiation;GO:0032504//multicellular organism reproduction;GO:0007283//spermatogenesis;GO:0035036//sperm-egg recognition;GO:0007338//single fertilization;GO:0007275//multicellular organismal development,-,-
57829,0,0,0,0,0,0,0,3,13,0,3,0,ZP4;zona pellucida glycoprotein 4,GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:2000344//positive regulation of acrosome reaction;GO:0070528//protein kinase C signaling;GO:0032504//multicellular organism reproduction;GO:0035556//intracellular signal transduction;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:0007339//binding of sperm to zona pellucida;GO:0060478//acrosomal vesicle exocytosis;GO:0042102//positive regulation of T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0010737//protein kinase A signaling;GO:0007338//single fertilization;GO:0002922//positive regulation of humoral immune response,GO:0032190//acrosin binding;GO:0004871//signal transducer activity,K13912//Salivary secretion
5783,0,0,0,38,124,51,62,4,137,0,0,0,"PTPN13;protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)",GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030027//lamellipodium;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity,-
57830,0,0,0,0,0,0,0,0,9,0,0,0,KRTAP5-8;keratin associated protein 5-8,GO:0045095//keratin filament,-,GO:0030280//structural constituent of epidermis,-
57834,0,17,0,526,33,6,0,127,0,0,50,421,"CYP4F11;cytochrome P450, family 4, subfamily F, polypeptide 11",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0006954//inflammatory response;GO:0042376//phylloquinone catabolic process;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process,"GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0020037//heme binding;GO:0070330//aromatase activity;GO:0005506//iron ion binding",K00490//Arachidonic acid metabolism;Metabolic pathways
57835,3,50,227,78,111,37,66,85,235,0,175,0,"SLC4A5;solute carrier family 4 (sodium bicarbonate cotransporter), member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0002064//epithelial cell development;GO:0033326//cerebrospinal fluid secretion;GO:0060041//retina development in camera-type eye;GO:0003014//renal system process;GO:0048311//mitochondrion distribution;GO:0003073//regulation of systemic arterial blood pressure;GO:0010468//regulation of gene expression;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0015701//bicarbonate transport;GO:0035725//sodium ion transmembrane transport,GO:0008510//sodium:bicarbonate symporter activity;GO:0005452//inorganic anion exchanger activity,K13857//Bile secretion
5784,71,1,0,8,30,37,11,132,45,0,14,0,"PTPN14;protein tyrosine phosphatase, non-receptor type 14",GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0001946//lymphangiogenesis;GO:0006351//transcription, DNA-templated;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0008285//negative regulation of cell proliferation;GO:0046825//regulation of protein export from nucleus;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0030971//receptor tyrosine kinase binding;GO:0003712//transcription cofactor activity,-
5786,0,0,0,0,40,16,0,65,42,0,14,0,"PTPRA;protein tyrosine phosphatase, receptor type, A",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0007411//axon guidance;GO:0006468//protein phosphorylation;GO:0008286//insulin receptor signaling pathway,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,-
57862,0,30,65,30,60,3,0,1,36,0,20,0,ZNF410;zinc finger protein 410,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
57863,84,0,0,0,0,16,0,0,41,0,0,0,CADM3;cell adhesion molecule 3,GO:0005911//cell-cell junction;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034332//adherens junction organization;GO:0034329//cell junction assembly;GO:0008104//protein localization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization,GO:0042803//protein homodimerization activity,K06780//Cell adhesion molecules (CAMs)
57864,0,0,0,0,0,0,77,0,29,0,3,0,"SLC46A2;solute carrier family 46, member 2",GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0048538//thymus development;GO:0070233//negative regulation of T cell apoptotic process;GO:0043029//T cell homeostasis;GO:0055085//transmembrane transport;GO:0045580//regulation of T cell differentiation,GO:0015293//symporter activity,-
5787,0,0,0,0,0,24,108,0,66,0,15,0,"PTPRB;protein tyrosine phosphatase, receptor type, B",GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane,GO:0001525//angiogenesis;GO:0006796//phosphate-containing compound metabolic process;GO:0016311//dephosphorylation;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding,K05694//Adherens junction
5788,7,0,53,0,0,17,13,0,87,5,0,91,"PTPRC;protein tyrosine phosphatase, receptor type, C",GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0045121//membrane raft;GO:0016020//membrane,GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0050852//T cell receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0001915//negative regulation of T cell mediated cytotoxicity;GO:0007166//cell surface receptor signaling pathway;GO:2000473//positive regulation of hematopoietic stem cell migration;GO:0045860//positive regulation of protein kinase activity;GO:0044770//cell cycle phase transition;GO:0042102//positive regulation of T cell proliferation;GO:0051607//defense response to virus;GO:0007411//axon guidance;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0051726//regulation of cell cycle;GO:2000648//positive regulation of stem cell proliferation;GO:0050857//positive regulation of antigen receptor-mediated signaling pathway;GO:0016311//dephosphorylation;GO:0051209//release of sequestered calcium ion into cytosol;GO:0002244//hematopoietic progenitor cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0002378//immunoglobulin biosynthetic process;GO:0030217//T cell differentiation;GO:0006469//negative regulation of protein kinase activity;GO:0048539//bone marrow development;GO:0048864//stem cell development;GO:0042100//B cell proliferation,GO:0019901//protein kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,K06478//Cell adhesion molecules (CAMs);Primary immunodeficiency;T cell receptor signaling pathway;Fc gamma R-mediated phagocytosis
5789,104,0,0,0,0,49,17,45,92,98,11,239,"PTPRD;protein tyrosine phosphatase, receptor type, D",GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0097105//presynaptic membrane assembly;GO:0030182//neuron differentiation;GO:0006796//phosphate-containing compound metabolic process;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0050775//positive regulation of dendrite morphogenesis,GO:0005102//receptor binding;GO:0050839//cell adhesion molecule binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding,-
579,0,0,0,0,0,0,17,0,8,0,0,0,NKX3-2;NK3 homeobox 2,GO:0005634//nucleus,GO:0043066//negative regulation of apoptotic process;GO:0031016//pancreas development;GO:0048645//organ formation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060576//intestinal epithelial cell development;GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048705//skeletal system morphogenesis;GO:0007368//determination of left/right symmetry;GO:0048536//spleen development;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048706//embryonic skeletal system development;GO:0042474//middle ear morphogenesis,GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
5791,0,0,0,0,0,36,0,0,95,0,8,3,"PTPRE;protein tyrosine phosphatase, receptor type, E",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0033003//regulation of mast cell activation;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0046627//negative regulation of insulin receptor signaling pathway,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
5792,1,24,35,0,14,0,88,0,115,140,9,0,"PTPRF;protein tyrosine phosphatase, receptor type, F",GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0016477//cell migration;GO:1900121//negative regulation of receptor binding;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0007155//cell adhesion;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway,GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0008201//heparin binding;GO:0032403//protein complex binding,K05695//Adherens junction;Insulin signaling pathway;Cell adhesion molecules (CAMs)
5793,128,0,0,16,0,30,56,0,102,0,6,1,"PTPRG;protein tyrosine phosphatase, receptor type, G",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0010633//negative regulation of epithelial cell migration;GO:0007420//brain development;GO:0010977//negative regulation of neuron projection development;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0042802//identical protein binding,-
5794,5,0,0,0,0,6,5,0,41,0,1,0,"PTPRH;protein tyrosine phosphatase, receptor type, H",GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,GO:0006915//apoptotic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0005515//protein binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,-
5795,5,0,1,6,60,0,0,0,14,0,16,1,"PTPRJ;protein tyrosine phosphatase, receptor type, J",GO:0032587//ruffle membrane;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0001772//immunological synapse,GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0043116//negative regulation of vascular permeability;GO:0051894//positive regulation of focal adhesion assembly;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0030336//negative regulation of cell migration;GO:0050918//positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0001570//vasculogenesis;GO:0007507//heart development;GO:0043407//negative regulation of MAP kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0030155//regulation of cell adhesion;GO:0060242//contact inhibition;GO:0051898//negative regulation of protein kinase B signaling;GO:0048709//oligodendrocyte differentiation;GO:0045785//positive regulation of cell adhesion,GO:0005515//protein binding;GO:0016791//phosphatase activity;GO:0070097//delta-catenin binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding;GO:0051019//mitogen-activated protein kinase binding;GO:0008013//beta-catenin binding;GO:0045295//gamma-catenin binding;GO:0005161//platelet-derived growth factor receptor binding,K05698//Adherens junction
5796,0,0,0,7,15,10,35,0,41,130,0,0,"PTPRK;protein tyrosine phosphatase, receptor type, K",GO:0030425//dendrite;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005911//cell-cell junction;GO:0043025//neuronal cell body;GO:0001750//photoreceptor outer segment;GO:0030424//axon;GO:0031256//leading edge membrane;GO:0005912//adherens junction;GO:0005887//integral component of plasma membrane,"GO:0034614//cellular response to reactive oxygen species;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007165//signal transduction;GO:0016477//cell migration;GO:0048041//focal adhesion assembly;GO:0045786//negative regulation of cell cycle;GO:0010839//negative regulation of keratinocyte proliferation;GO:0030336//negative regulation of cell migration;GO:0007155//cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0034394//protein localization to cell surface;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034644//cellular response to UV;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation",GO:0045295//gamma-catenin binding;GO:0008013//beta-catenin binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0019901//protein kinase binding,-
5797,0,0,0,3,26,0,24,0,17,0,0,0,"PTPRM;protein tyrosine phosphatase, receptor type, M",GO:0005913//cell-cell adherens junction;GO:0005887//integral component of plasma membrane;GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005911//cell-cell junction,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0010842//retina layer formation;GO:0010596//negative regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis;GO:0042493//response to drug;GO:0045909//positive regulation of vasodilation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0031290//retinal ganglion cell axon guidance;GO:0007165//signal transduction;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0031175//neuron projection development,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042802//identical protein binding;GO:0045296//cadherin binding,K05693//Adherens junction;Cell adhesion molecules (CAMs)
5798,0,0,0,0,0,0,0,0,31,0,4,0,"PTPRN;protein tyrosine phosphatase, receptor type, N",GO:0005887//integral component of plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0032868//response to insulin;GO:0043627//response to estrogen;GO:0000302//response to reactive oxygen species;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0009749//response to glucose;GO:0051591//response to cAMP,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0051020//GTPase binding;GO:0030507//spectrin binding,K07817//Type I diabetes mellitus
5799,9,0,0,4,24,17,20,56,47,0,1,0,"PTPRN2;protein tyrosine phosphatase, receptor type, N polypeptide 2",GO:0030141//secretory granule;GO:0005788//endoplasmic reticulum lumen;GO:0043235//receptor complex;GO:0043195//terminal bouton;GO:0030658//transport vesicle membrane;GO:0005887//integral component of plasma membrane,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0034260//negative regulation of GTPase activity,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,K07817//Type I diabetes mellitus
58,0,0,0,0,0,0,16,0,0,0,0,0,"ACTA1;actin, alpha 1, skeletal muscle",GO:0005865//striated muscle thin filament;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005884//actin filament;GO:0001725//stress fiber;GO:0030017//sarcomere;GO:0015629//actin cytoskeleton;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0006936//muscle contraction;GO:0043503//skeletal muscle fiber adaptation;GO:0048545//response to steroid hormone;GO:0009612//response to mechanical stimulus;GO:0030240//skeletal muscle thin filament assembly;GO:0048741//skeletal muscle fiber development;GO:0016049//cell growth;GO:0010226//response to lithium ion;GO:0009991//response to extracellular stimulus;GO:0030049//muscle filament sliding,GO:0043531//ADP binding;GO:0005200//structural constituent of cytoskeleton;GO:0005524//ATP binding;GO:0017022//myosin binding;GO:0005515//protein binding,-
580,102,0,0,29,29,0,13,0,63,0,6,0,BARD1;BRCA1 associated RING domain 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0005730//nucleolus;GO:0031436//BRCA1-BARD1 complex;GO:0070531//BRCA1-A complex;GO:0043231//intracellular membrane-bounded organelle,GO:0085020//protein K6-linked ubiquitination;GO:0043065//positive regulation of apoptotic process;GO:0031441//negative regulation of mRNA 3'-end processing;GO:0043066//negative regulation of apoptotic process;GO:0046826//negative regulation of protein export from nucleus;GO:0016567//protein ubiquitination;GO:0001894//tissue homeostasis;GO:0006974//cellular response to DNA damage stimulus;GO:0042325//regulation of phosphorylation;GO:0006281//DNA repair;GO:0045732//positive regulation of protein catabolic process;GO:0007050//cell cycle arrest,GO:0019900//kinase binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003723//RNA binding;GO:0016874//ligase activity,-
5800,0,0,0,0,0,0,51,28,166,0,0,0,"PTPRO;protein tyrosine phosphatase, receptor type, O",GO:0030027//lamellipodium;GO:0016328//lateral plasma membrane;GO:0043197//dendritic spine;GO:0016324//apical plasma membrane;GO:0030426//growth cone;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0030424//axon,GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0000902//cell morphogenesis;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0036060//slit diaphragm assembly;GO:0030032//lamellipodium assembly;GO:0010812//negative regulation of cell-substrate adhesion;GO:0007411//axon guidance;GO:0002548//monocyte chemotaxis;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0032835//glomerulus development;GO:0010977//negative regulation of neuron projection development;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:0003105//negative regulation of glomerular filtration;GO:0003093//regulation of glomerular filtration,GO:0016791//phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0042803//protein homodimerization activity;GO:0017147//Wnt-protein binding,-
5801,0,0,0,0,0,1,17,0,53,0,0,0,"PTPRR;protein tyrosine phosphatase, receptor type, R",GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm,GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001701//in utero embryonic development;GO:0010633//negative regulation of epithelial cell migration,GO:0019901//protein kinase binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,K04458//MAPK signaling pathway
5802,0,17,0,0,4,79,30,70,40,0,0,0,"PTPRS;protein tyrosine phosphatase, receptor type, S",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0021549//cerebellum development;GO:0030198//extracellular matrix organization;GO:0021510//spinal cord development;GO:0021766//hippocampus development;GO:0021987//cerebral cortex development;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0022038//corpus callosum development;GO:0007155//cell adhesion,GO:0005001//transmembrane receptor protein tyrosine phosphatase activity;GO:0005515//protein binding,-
5803,0,0,0,0,0,0,83,63,57,141,0,0,"PTPRZ1;protein tyrosine phosphatase, receptor-type, Z polypeptide 1",GO:0005887//integral component of plasma membrane;GO:0072534//perineuronal net;GO:0005578//proteinaceous extracellular matrix,GO:0007409//axonogenesis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0007611//learning or memory;GO:0048709//oligodendrocyte differentiation;GO:0070445//regulation of oligodendrocyte progenitor proliferation;GO:0007417//central nervous system development;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0005001//transmembrane receptor protein tyrosine phosphatase activity,K08114//Epithelial cell signaling in Helicobacter pylori infection
5805,0,16,0,18,14,0,0,0,0,0,0,0,PTS;6-pyruvoyltetrahydropterin synthase,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0046209//nitric oxide metabolic process;GO:0007417//central nervous system development;GO:0006520//cellular amino acid metabolic process;GO:0044281//small molecule metabolic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0006729//tetrahydrobiopterin biosynthetic process,GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0003874//6-pyruvoyltetrahydropterin synthase activity,K01737//Folate biosynthesis;Metabolic pathways
5806,0,0,0,0,0,0,0,0,8,0,0,0,"PTX3;pentraxin 3, long",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0001878//response to yeast;GO:0046597//negative regulation of viral entry into host cell;GO:1903016//negative regulation of exo-alpha-sialidase activity;GO:0045087//innate immune response;GO:0008228//opsonization;GO:1903019//negative regulation of glycoprotein metabolic process;GO:0006954//inflammatory response;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050766//positive regulation of phagocytosis,GO:0001872//(1->3)-beta-D-glucan binding;GO:0001849//complement component C1q binding;GO:0046790//virion binding,K01672//Pancreatic secretion;Nitrogen metabolism;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Collecting duct acid secretion
581,0,0,0,4,0,0,2,0,0,0,3,0,BAX;BCL2-associated X protein,GO:0005739//mitochondrion;GO:0046930//pore complex;GO:0005757//mitochondrial permeability transition pore complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0097144//BAX complex;GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0016020//membrane;GO:0097136//Bcl-2 family protein complex;GO:0005783//endoplasmic reticulum,GO:0032461//positive regulation of protein oligomerization;GO:0043524//negative regulation of neuron apoptotic process;GO:0008637//apoptotic mitochondrial changes;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response;GO:0021987//cerebral cortex development;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0051881//regulation of mitochondrial membrane potential;GO:0048515//spermatid differentiation;GO:0035234//ectopic germ cell programmed cell death;GO:0097296//activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0048678//response to axon injury;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0097190//apoptotic signaling pathway;GO:1990009//retinal cell apoptotic process;GO:0048597//post-embryonic camera-type eye morphogenesis;GO:0045136//development of secondary sexual characteristics;GO:0002358//B cell homeostatic proliferation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0009636//response to toxic substance;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0001822//kidney development;GO:0002262//myeloid cell homeostasis;GO:0021854//hypothalamus development;GO:0043525//positive regulation of neuron apoptotic process;GO:0002352//B cell negative selection;GO:0051726//regulation of cell cycle;GO:1990117//B cell receptor apoptotic signaling pathway;GO:0043497//regulation of protein heterodimerization activity;GO:0008053//mitochondrial fusion;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0048147//negative regulation of fibroblast proliferation;GO:0009566//fertilization;GO:0051260//protein homooligomerization;GO:0070584//mitochondrion morphogenesis;GO:0001974//blood vessel remodeling;GO:0010332//response to gamma radiation;GO:0070242//thymocyte apoptotic process;GO:0006808//regulation of nitrogen utilization;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0051402//neuron apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042475//odontogenesis of dentin-containing tooth;GO:0016032//viral process;GO:0060041//retina development in camera-type eye;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:1902512//positive regulation of apoptotic DNA fragmentation;GO:0001764//neuron migration;GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0043496//regulation of protein homodimerization activity;GO:0046666//retinal cell programmed cell death;GO:0060011//Sertoli cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0051259//protein oligomerization;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1902262//apoptotic process involved in patterning of blood vessels;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0001777//T cell homeostatic proliferation;GO:0071310//cellular response to organic substance;GO:0032091//negative regulation of protein binding;GO:0009651//response to salt stress;GO:0048087//positive regulation of developmental pigmentation;GO:0032976//release of matrix enzymes from mitochondria;GO:0001836//release of cytochrome c from mitochondria;GO:0006915//apoptotic process;GO:1902263//apoptotic process involved in embryonic digit morphogenesis;GO:0001541//ovarian follicle development;GO:0001782//B cell homeostasis;GO:0097191//extrinsic apoptotic signaling pathway;GO:0001783//B cell apoptotic process;GO:0006687//glycosphingolipid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0007281//germ cell development;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060068//vagina development;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0006927//transformed cell apoptotic process;GO:0034644//cellular response to UV;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0048873//homeostasis of number of cells within a tissue;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0002904//positive regulation of B cell apoptotic process,GO:0008289//lipid binding;GO:0051434//BH3 domain binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0015267//channel activity,K02159//Tuberculosis;Pathways in cancer;Huntington's disease;HTLV-I infection;p53 signaling pathway;Colorectal cancer;Prion diseases;Protein processing in endoplasmic reticulum;Apoptosis;Amyotrophic lateral sclerosis (ALS);Neurotrophin signaling pathway
5810,119,0,41,23,68,3,0,0,81,0,0,0,RAD1;RAD1 homolog (S. pombe),GO:0043231//intracellular membrane-bounded organelle;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0000077//DNA damage checkpoint;GO:0071479//cellular response to ionizing radiation;GO:0051598//meiotic recombination checkpoint;GO:0006974//cellular response to DNA damage stimulus;GO:0021762//substantia nigra development;GO:0006281//DNA repair;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000738//DNA catabolic process, exonucleolytic;GO:0006260//DNA replication",GO:0003684//damaged DNA binding;GO:0008853//exodeoxyribonuclease III activity;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity,K02830//Cell cycle - yeast;Meiosis - yeast
5813,39,18,0,20,38,16,0,20,36,0,36,0,PURA;purine-rich element binding protein A,"GO:0030425//dendrite;GO:0005662//DNA replication factor A complex;GO:0000784//nuclear chromosome, telomeric region;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005634//nucleus","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0017148//negative regulation of translation;GO:0006268//DNA unwinding involved in DNA replication;GO:0008284//positive regulation of cell proliferation;GO:0007399//nervous system development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006270//DNA replication initiation","GO:0046332//SMAD binding;GO:0003691//double-stranded telomeric DNA binding;GO:0003697//single-stranded DNA binding;GO:0000900//translation repressor activity, nucleic acid binding;GO:0032422//purine-rich negative regulatory element binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008134//transcription factor binding",-
5814,93,31,21,40,136,24,28,32,39,0,20,0,PURB;purine-rich element binding protein B,GO:0005662//DNA replication factor A complex;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0045637//regulation of myeloid cell differentiation;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003697//single-stranded DNA binding;GO:0008134//transcription factor binding;GO:0003729//mRNA binding;GO:0003690//double-stranded DNA binding;GO:0046332//SMAD binding,K11447//Transcriptional misregulation in cancer
58157,0,0,0,0,0,14,4,0,35,0,1,0,NGB;neuroglobin,GO:0005739//mitochondrion;GO:0043204//perikaryon,GO:0006915//apoptotic process;GO:0015671//oxygen transport,GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0005506//iron ion binding;GO:0005344//oxygen transporter activity,-
58158,0,0,0,1,0,16,14,0,23,0,0,285,NEUROD4;neuronal differentiation 4,GO:0005634//nucleus,"GO:0048666//neuron development;GO:0010001//glial cell differentiation;GO:0007219//Notch signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0045165//cell fate commitment;GO:0007405//neuroblast proliferation;GO:0006351//transcription, DNA-templated;GO:0045597//positive regulation of cell differentiation;GO:0035881//amacrine cell differentiation;GO:0001764//neuron migration",GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
5817,0,0,0,0,0,17,1,13,24,0,6,0,PVR;poliovirus receptor,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0016032//viral process;GO:0060370//susceptibility to T cell mediated cytotoxicity;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0050776//regulation of immune response;GO:0034332//adherens junction organization;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0045216//cell-cell junction organization;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0007155//cell adhesion;GO:0034329//cell junction assembly,GO:0004872//receptor activity;GO:0050839//cell adhesion molecule binding;GO:0005515//protein binding,K06539//Cell adhesion molecules (CAMs)
5818,66,0,0,0,0,13,12,18,39,184,0,0,PVRL1;poliovirus receptor-related 1 (herpesvirus entry mediator C),GO:0005913//cell-cell adherens junction;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0032584//growth cone membrane;GO:0005912//adherens junction;GO:0043231//intracellular membrane-bounded organelle;GO:0030424//axon,GO:0034332//adherens junction organization;GO:0070166//enamel mineralization;GO:0045216//cell-cell junction organization;GO:0002089//lens morphogenesis in camera-type eye;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0006826//iron ion transport;GO:0009615//response to virus;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0007411//axon guidance;GO:0006955//immune response;GO:0007165//signal transduction;GO:0060041//retina development in camera-type eye;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0002934//desmosome organization;GO:0051963//regulation of synapse assembly;GO:0046718//viral entry into host cell,GO:0046790//virion binding;GO:0015026//coreceptor activity;GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0030246//carbohydrate binding;GO:0050839//cell adhesion molecule binding,K06081//Adherens junction;Herpes simplex infection;Cell adhesion molecules (CAMs)
58189,0,0,0,0,0,0,17,0,0,0,0,0,WFDC1;WAP four-disulfide core domain 1,GO:0005615//extracellular space,GO:0050680//negative regulation of epithelial cell proliferation;GO:0032355//response to estradiol;GO:0030308//negative regulation of cell growth;GO:0010951//negative regulation of endopeptidase activity;GO:0042493//response to drug,GO:0004867//serine-type endopeptidase inhibitor activity,K01537//Purine metabolism
5819,0,6,0,0,10,22,0,73,50,68,59,0,PVRL2;poliovirus receptor-related 2 (herpesvirus entry mediator B),GO:0005915//zonula adherens;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0060370//susceptibility to T cell mediated cytotoxicity;GO:0051654//establishment of mitochondrion localization;GO:0033005//positive regulation of mast cell activation;GO:0007286//spermatid development;GO:0030382//sperm mitochondrion organization;GO:0007165//signal transduction;GO:0019064//fusion of virus membrane with host plasma membrane;GO:0002860//positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;GO:0009566//fertilization;GO:0044406//adhesion of symbiont to host;GO:0042271//susceptibility to natural killer cell mediated cytotoxicity;GO:0045216//cell-cell junction organization;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034332//adherens junction organization;GO:0044782//cilium organization;GO:0032990//cell part morphogenesis;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0007289//spermatid nucleus differentiation;GO:0001675//acrosome assembly;GO:0046814//coreceptor-mediated virion attachment to host cell;GO:0007010//cytoskeleton organization;GO:0009615//response to virus;GO:0034329//cell junction assembly;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0001618//virus receptor activity;GO:0015026//coreceptor activity,K06531//Adherens junction;Herpes simplex infection;Cell adhesion molecules (CAMs)
58190,1,23,2,12,31,43,34,0,3,0,5,0,"CTDSP1;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1",GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0050768//negative regulation of neurogenesis;GO:0006470//protein dephosphorylation;GO:0045665//negative regulation of neuron differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0008420//CTD phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
58191,0,0,61,8,6,0,11,65,30,0,19,0,CXCL16;chemokine (C-X-C motif) ligand 16,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0048247//lymphocyte chemotaxis;GO:0006898//receptor-mediated endocytosis;GO:0034612//response to tumor necrosis factor;GO:0030307//positive regulation of cell growth;GO:0006935//chemotaxis;GO:0034097//response to cytokine;GO:0030335//positive regulation of cell migration;GO:0034341//response to interferon-gamma,GO:0005041//low-density lipoprotein receptor activity;GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0005044//scavenger receptor activity,K10035//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
582,0,22,0,0,33,6,33,0,20,0,6,0,BBS1;Bardet-Biedl syndrome 1,GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0005815//microtubule organizing center;GO:0034464//BBSome,GO:0001895//retina homeostasis;GO:0043001//Golgi to plasma membrane protein transport;GO:0045494//photoreceptor cell maintenance;GO:0050896//response to stimulus;GO:0042384//cilium assembly;GO:0007601//visual perception;GO:0035058//nonmotile primary cilium assembly,GO:0005119//smoothened binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0005113//patched binding;GO:0005515//protein binding,-
5822,116,0,0,0,0,1,0,59,27,138,28,0,PWP2;PWP2 periodic tryptophan protein homolog (yeast),GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0007165//signal transduction,GO:0004871//signal transducer activity;GO:0044822//poly(A) RNA binding,K14558//Ribosome biogenesis in eukaryotes
5824,0,13,1,48,195,6,0,0,4,0,0,0,PEX19;peroxisomal biogenesis factor 19,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005778//peroxisomal membrane;GO:0031526//brush border membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0043234//protein complex,GO:0072321//chaperone-mediated protein transport;GO:0055085//transmembrane transport;GO:0050821//protein stabilization;GO:0007031//peroxisome organization;GO:0016557//peroxisome membrane biogenesis;GO:0061077//chaperone-mediated protein folding;GO:1900131//negative regulation of lipid binding;GO:0016559//peroxisome fission;GO:0006625//protein targeting to peroxisome;GO:0045046//protein import into peroxisome membrane,GO:0036105//peroxisome membrane class-1 targeting sequence binding;GO:0047485//protein N-terminus binding;GO:0051117//ATPase binding;GO:0005515//protein binding,K13337//Peroxisome
5825,0,0,0,14,41,0,22,0,23,0,0,0,"ABCD3;ATP-binding cassette, sub-family D (ALD), member 3",GO:0005743//mitochondrial inner membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005782//peroxisomal matrix;GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005777//peroxisome,GO:0006635//fatty acid beta-oxidation;GO:0042760//very long-chain fatty acid catabolic process;GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0007031//peroxisome organization,"GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005515//protein binding;GO:0042803//protein homodimerization activity",K05677//ABC transporters;Peroxisome
5826,0,0,0,0,10,0,15,44,13,0,0,0,"ABCD4;ATP-binding cassette, sub-family D (ALD), member 4",GO:0005789//endoplasmic reticulum membrane;GO:0005777//peroxisome;GO:0043190//ATP-binding cassette (ABC) transporter complex;GO:0016021//integral component of membrane;GO:0005778//peroxisomal membrane,GO:0009235//cobalamin metabolic process;GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding",K05678//ABC transporters;Peroxisome
5827,0,24,0,0,21,5,0,0,0,0,0,1,"PXMP2;peroxisomal membrane protein 2, 22kDa",GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0043234//protein complex,-,GO:0005515//protein binding,K13347//Peroxisome
5828,0,53,0,7,72,36,0,0,75,0,0,0,PEX2;peroxisomal biogenesis factor 2,GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane;GO:0016020//membrane;GO:0016593//Cdc73/Paf1 complex,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006699//bile acid biosynthetic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0031648//protein destabilization;GO:0007031//peroxisome organization;GO:0042632//cholesterol homeostasis;GO:0045540//regulation of cholesterol biosynthetic process;GO:0001764//neuron migration;GO:0006635//fatty acid beta-oxidation;GO:0016558//protein import into peroxisome matrix;GO:0050680//negative regulation of epithelial cell proliferation;GO:0000038//very long-chain fatty acid metabolic process,GO:0008270//zinc ion binding;GO:0005515//protein binding,K06664//Peroxisome
5829,0,173,0,40,85,28,29,199,46,0,82,0,PXN;paxillin,GO:0005634//nucleus;GO:0001725//stress fiber;GO:0005730//nucleolus;GO:0005875//microtubule associated complex;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0030027//lamellipodium;GO:0005886//plasma membrane,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007010//cytoskeleton organization;GO:0034329//cell junction assembly;GO:0008360//regulation of cell shape;GO:0000187//activation of MAPK activity;GO:0048754//branching morphogenesis of an epithelial tube;GO:0034614//cellular response to reactive oxygen species;GO:0060396//growth hormone receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007172//signal complex assembly;GO:0030032//lamellipodium assembly;GO:0006936//muscle contraction;GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0007229//integrin-mediated signaling pathway;GO:0007165//signal transduction;GO:0034446//substrate adhesion-dependent cell spreading;GO:0048041//focal adhesion assembly;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0008270//zinc ion binding;GO:0019901//protein kinase binding;GO:0051435//BH4 domain binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0017166//vinculin binding;GO:0008013//beta-catenin binding,K05760//Chemokine signaling pathway;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;VEGF signaling pathway;Focal adhesion
583,0,23,0,11,19,12,57,0,15,12,30,0,BBS2;Bardet-Biedl syndrome 2,GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0031514//motile cilium;GO:0036064//ciliary basal body;GO:0034464//BBSome,GO:0007601//visual perception;GO:0035058//nonmotile primary cilium assembly;GO:0032402//melanosome transport;GO:0045444//fat cell differentiation;GO:0043001//Golgi to plasma membrane protein transport;GO:0014824//artery smooth muscle contraction;GO:0040018//positive regulation of multicellular organism growth;GO:0033365//protein localization to organelle;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0042311//vasodilation;GO:0030534//adult behavior;GO:0021987//cerebral cortex development;GO:0021756//striatum development;GO:0021766//hippocampus development;GO:0051216//cartilage development;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0010629//negative regulation of gene expression;GO:0060271//cilium morphogenesis;GO:0040015//negative regulation of multicellular organism growth;GO:0008104//protein localization;GO:0007288//sperm axoneme assembly;GO:0048854//brain morphogenesis;GO:0045494//photoreceptor cell maintenance,GO:0005515//protein binding;GO:0001103//RNA polymerase II repressing transcription factor binding,-
5830,0,30,0,0,0,0,0,15,30,0,0,0,PEX5;peroxisomal biogenesis factor 5,GO:0043234//protein complex;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005622//intracellular,"GO:0016558//protein import into peroxisome matrix;GO:0007029//endoplasmic reticulum organization;GO:0021795//cerebral cortex cell migration;GO:0050905//neuromuscular process;GO:0001764//neuron migration;GO:0016561//protein import into peroxisome matrix, translocation;GO:0006625//protein targeting to peroxisome;GO:0040018//positive regulation of multicellular organism growth;GO:0006635//fatty acid beta-oxidation;GO:0051262//protein tetramerization;GO:0016560//protein import into peroxisome matrix, docking;GO:0021895//cerebral cortex neuron differentiation;GO:0045046//protein import into peroxisome membrane;GO:0000038//very long-chain fatty acid metabolic process;GO:1901094//negative regulation of protein homotetramerization;GO:0048468//cell development;GO:0007006//mitochondrial membrane organization",GO:0008022//protein C-terminus binding;GO:0047485//protein N-terminus binding;GO:0019899//enzyme binding;GO:0000268//peroxisome targeting sequence binding;GO:0005052//peroxisome matrix targeting signal-1 binding;GO:0031267//small GTPase binding;GO:0005515//protein binding,K13342//Peroxisome
5831,0,12,0,0,14,0,0,0,26,0,37,0,PYCR1;pyrroline-5-carboxylate reductase 1,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0034641//cellular nitrogen compound metabolic process;GO:0008652//cellular amino acid biosynthetic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0006561//proline biosynthetic process;GO:0055129//L-proline biosynthetic process;GO:0034599//cellular response to oxidative stress,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004735//pyrroline-5-carboxylate reductase activity,"K00286//Glycine, serine and threonine metabolism;Methane metabolism;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Arginine and proline metabolism;Metabolic pathways;Propanoate metabolism;Pyruvate metabolism;Two-component system"
5832,223,27,0,20,33,0,0,19,31,0,10,0,"ALDH18A1;aldehyde dehydrogenase 18 family, member A1",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0019240//citrulline biosynthetic process;GO:0055114//oxidation-reduction process;GO:0008652//cellular amino acid biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006536//glutamate metabolic process;GO:0006592//ornithine biosynthetic process;GO:0016310//phosphorylation;GO:0044281//small molecule metabolic process;GO:0006561//proline biosynthetic process;GO:0055129//L-proline biosynthetic process,GO:0004349//glutamate 5-kinase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0004350//glutamate-5-semialdehyde dehydrogenase activity,K12657//Metabolic pathways;Arginine and proline metabolism
5833,82,0,3,9,0,0,0,0,13,0,0,0,"PCYT2;phosphate cytidylyltransferase 2, ethanolamine",GO:0005789//endoplasmic reticulum membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0008654//phospholipid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0004306//ethanolamine-phosphate cytidylyltransferase activity,K00967//Glycerophospholipid metabolism;Metabolic pathways
5834,0,46,3,15,71,24,3,50,11,0,0,406,"PYGB;phosphorylase, glycogen; brain",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,GO:0008184//glycogen phosphorylase activity;GO:0030170//pyridoxal phosphate binding,K00688//Insulin signaling pathway;Starch and sucrose metabolism
5836,0,0,21,0,70,0,42,0,26,0,0,182,"PYGL;phosphorylase, glycogen, liver",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0005977//glycogen metabolic process;GO:0005980//glycogen catabolic process;GO:0005975//carbohydrate metabolic process;GO:0042593//glucose homeostasis;GO:0006015//5-phosphoribose 1-diphosphate biosynthetic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0070266//necroptotic process,GO:0042803//protein homodimerization activity;GO:0016208//AMP binding;GO:0002060//purine nucleobase binding;GO:0030170//pyridoxal phosphate binding;GO:0032052//bile acid binding;GO:0008184//glycogen phosphorylase activity;GO:0008144//drug binding;GO:0005524//ATP binding;GO:0005536//glucose binding;GO:0019842//vitamin binding,K00688//Starch and sucrose metabolism;Insulin signaling pathway
5837,0,0,0,0,0,34,20,53,62,132,6,0,"PYGM;phosphorylase, glycogen, muscle",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0005980//glycogen catabolic process;GO:0044281//small molecule metabolic process;GO:0005977//glycogen metabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,GO:0000166//nucleotide binding;GO:0008184//glycogen phosphorylase activity;GO:0030170//pyridoxal phosphate binding,K00688//Insulin signaling pathway;Starch and sucrose metabolism
58472,43,0,1,33,103,7,3,0,15,0,10,0,SQRDL;sulfide quinone reductase-like (yeast),GO:0005743//mitochondrial inner membrane,"GO:0044281//small molecule metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000098//sulfur amino acid catabolic process;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase",GO:0070224//sulfide:quinone oxidoreductase activity,-
58473,77,0,0,1,67,31,38,0,14,87,0,562,"PLEKHB1;pleckstrin homology domain containing, family B (evectins) member 1",GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0045595//regulation of cell differentiation;GO:0007275//multicellular organismal development;GO:0007602//phototransduction,GO:0008022//protein C-terminus binding;GO:0004871//signal transducer activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
58475,15,0,0,0,0,0,0,0,9,157,0,0,"MS4A7;membrane-spanning 4-domains, subfamily A, member 7",GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
58476,0,0,1,0,0,16,23,0,8,0,0,0,TP53INP2;tumor protein p53 inducible nuclear protein 2,GO:0031410//cytoplasmic vesicle;GO:0005634//nucleus;GO:0005776//autophagic vacuole;GO:0005829//cytosol;GO:0016605//PML body,"GO:0000045//autophagic vacuole assembly;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001649//osteoblast differentiation;GO:0010508//positive regulation of autophagy",GO:0005515//protein binding,K15310//HTLV-I infection
58477,0,0,0,0,0,11,0,0,12,0,14,0,"SRPRB;signal recognition particle receptor, B subunit",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005881//cytoplasmic microtubule;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0007264//small GTPase mediated signal transduction;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process,GO:0005525//GTP binding,K12272//Protein export
58478,0,5,0,52,95,0,0,0,0,0,7,0,ENOPH1;enolase-phosphatase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0016311//dephosphorylation;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0000096//sulfur amino acid metabolic process,GO:0043874//acireductone synthase activity;GO:0000287//magnesium ion binding,K09880//Cysteine and methionine metabolism
58480,0,3,1,43,316,17,19,0,43,0,6,6,RHOU;ras homolog family member U,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0042995//cell projection;GO:0002102//podosome,GO:0016601//Rac protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization;GO:0030036//actin cytoskeleton organization;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
58484,0,0,43,4,0,0,26,0,0,0,9,0,"NLRC4;NLR family, CARD domain containing 4",GO:0005622//intracellular;GO:0005829//cytosol;GO:0072557//IPAF inflammasome complex,"GO:0042742//defense response to bacterium;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0050702//interleukin-1 beta secretion;GO:0016045//detection of bacterium;GO:0070269//pyroptosis;GO:0002218//activation of innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051260//protein homooligomerization;GO:0006954//inflammatory response;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response",GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,K12805//Salmonella infection;Legionellosis;NOD-like receptor signaling pathway
58485,0,0,0,0,41,0,0,0,0,0,0,0,TRAPPC1;trafficking protein particle complex 1,GO:0030008//TRAPP complex;GO:0005801//cis-Golgi network;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0006888//ER to Golgi vesicle-mediated transport,-,-
58486,0,27,0,0,21,0,0,0,9,0,0,0,"ZBED5;zinc finger, BED-type containing 5",-,-,GO:0003677//DNA binding;GO:0046872//metal ion binding,K06103//Tight junction;K06115//Tight junction
58487,0,0,0,8,4,30,15,0,16,20,0,178,CREBZF;CREB/ATF bZIP transcription factor,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0006351//transcription, DNA-templated;GO:0045814//negative regulation of gene expression, epigenetic;GO:0009615//response to virus",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042802//identical protein binding,-
58488,0,0,0,6,9,0,0,0,30,0,0,0,PCTP;phosphatidylcholine transfer protein,GO:0005829//cytosol,GO:0015914//phospholipid transport;GO:0006869//lipid transport;GO:0008203//cholesterol metabolic process,GO:0008525//phosphatidylcholine transporter activity;GO:0031210//phosphatidylcholine binding,-
58489,0,24,1,18,85,0,0,2,0,0,0,0,ABHD17C;abhydrolase domain containing 17C,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
58490,0,1,0,18,26,0,0,0,12,0,0,0,RPRD1B;regulation of nuclear pre-mRNA domain containing 1B,"GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005634//nucleus","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain;GO:0010564//regulation of cell cycle process",GO:0005515//protein binding;GO:0000993//RNA polymerase II core binding,-
58491,0,0,0,0,6,8,0,0,7,0,0,0,ZNF71;zinc finger protein 71,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
58492,0,0,0,0,28,0,0,0,27,0,0,0,ZNF77;zinc finger protein 77,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
58493,0,0,0,0,0,0,0,0,1,0,0,0,INIP;INTS3 and NABP interacting protein,GO:0005634//nucleus;GO:0070876//SOSS complex;GO:0005730//nucleolus,GO:0006974//cellular response to DNA damage stimulus;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
58494,25,0,1,1,0,0,0,0,10,0,9,0,JAM2;junctional adhesion molecule 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0016337//single organismal cell-cell adhesion;GO:0050900//leukocyte migration;GO:0030198//extracellular matrix organization;GO:0007162//negative regulation of cell adhesion;GO:0007596//blood coagulation,GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K06735//Epithelial cell signaling in Helicobacter pylori infection;Leukocyte transendothelial migration;Tight junction;Cell adhesion molecules (CAMs)
58495,0,0,0,0,1,33,0,0,0,0,1,0,OVOL2;ovo-like zinc finger 2,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001755//neural crest cell migration;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0045746//negative regulation of Notch signaling pathway;GO:0060214//endocardium formation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0045617//negative regulation of keratinocyte differentiation;GO:0010837//regulation of keratinocyte proliferation;GO:0001525//angiogenesis;GO:0048557//embryonic digestive tract morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008285//negative regulation of cell proliferation;GO:0051726//regulation of cell cycle;GO:0001842//neural fold formation;GO:0009953//dorsal/ventral pattern formation;GO:0060347//heart trabecula formation;GO:0001947//heart looping;GO:0060716//labyrinthine layer blood vessel development",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
58497,1,0,1,2,12,8,26,0,33,0,0,0,PRUNE;prune exopolyphosphatase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005925//focal adhesion,GO:0008152//metabolic process,GO:0004427//inorganic diphosphatase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K01514//Purine metabolism
58498,0,0,0,0,0,0,0,0,20,0,0,0,"MYL7;myosin, light chain 7, regulatory",GO:0031672//A band;GO:0016459//myosin complex;GO:0043197//dendritic spine,-,GO:0005509//calcium ion binding,K12754//Regulation of actin cytoskeleton;Tight junction;Focal adhesion;Leukocyte transendothelial migration
58499,17,22,0,86,272,17,2,0,35,0,0,0,ZNF462;zinc finger protein 462,GO:0005634//nucleus,"GO:0043392//negative regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
585,0,1,0,8,15,33,52,0,29,0,27,0,BBS4;Bardet-Biedl syndrome 4,GO:0036064//ciliary basal body;GO:0034464//BBSome;GO:0005813//centrosome;GO:0031513//nonmotile primary cilium;GO:0060170//ciliary membrane;GO:0000242//pericentriolar material;GO:0034451//centriolar satellite;GO:0031514//motile cilium;GO:0005814//centriole;GO:0005929//cilium,GO:0007601//visual perception;GO:0035058//nonmotile primary cilium assembly;GO:0016358//dendrite development;GO:0001843//neural tube closure;GO:0032402//melanosome transport;GO:0051877//pigment granule aggregation in cell center;GO:0046548//retinal rod cell development;GO:0051457//maintenance of protein location in nucleus;GO:0040018//positive regulation of multicellular organism growth;GO:0000226//microtubule cytoskeleton organization;GO:0021987//cerebral cortex development;GO:0021766//hippocampus development;GO:0046907//intracellular transport;GO:0060271//cilium morphogenesis;GO:0010629//negative regulation of gene expression;GO:0045494//photoreceptor cell maintenance;GO:0007608//sensory perception of smell;GO:0048854//brain morphogenesis;GO:0032465//regulation of cytokinesis;GO:0071539//protein localization to centrosome;GO:0045444//fat cell differentiation;GO:0007286//spermatid development;GO:0034454//microtubule anchoring at centrosome;GO:0042384//cilium assembly;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0033365//protein localization to organelle;GO:0030534//adult behavior;GO:0001895//retina homeostasis;GO:0021756//striatum development;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0050893//sensory processing;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0000281//mitotic cytokinesis;GO:0060027//convergent extension involved in gastrulation;GO:0045724//positive regulation of cilium assembly;GO:0008152//metabolic process;GO:0019216//regulation of lipid metabolic process;GO:0015031//protein transport;GO:0051297//centrosome organization;GO:0001947//heart looping,GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0034452//dynactin binding;GO:0048487//beta-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding,K09553//Prion diseases;K03350//Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;Cell cycle;Oocyte meiosis;HTLV-I infection;Meiosis - yeast;K13137//RNA transport
58500,0,23,0,10,30,13,34,0,65,0,0,0,ZNF250;zinc finger protein 250,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
58503,0,0,0,0,0,3,0,0,0,0,0,0,"PROL1;proline rich, lacrimal 1",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0051930//regulation of sensory perception of pain;GO:0010951//negative regulation of endopeptidase activity;GO:0001895//retina homeostasis,GO:0030414//peptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity,-
58504,0,0,0,0,0,16,0,0,58,0,0,0,ARHGAP22;Rho GTPase activating protein 22,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0001525//angiogenesis;GO:0043547//positive regulation of GTPase activity;GO:0030154//cell differentiation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006351//transcription, DNA-templated;GO:0007264//small GTPase mediated signal transduction",GO:0005515//protein binding;GO:0005096//GTPase activator activity,K07526//Axon guidance
58505,0,0,0,9,5,6,14,0,19,0,0,0,OSTC;oligosaccharyltransferase complex subunit (non-catalytic),GO:0008250//oligosaccharyltransferase complex;GO:0016021//integral component of membrane,GO:0018279//protein N-linked glycosylation via asparagine,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity,-
58506,163,1,0,2,27,8,14,1,32,0,8,0,SCAF1;SR-related CTD-associated factor 1,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0019904//protein domain specific binding;GO:0003723//RNA binding,-
58508,79,138,1,73,284,62,54,0,81,122,54,0,KMT2C;lysine (K)-specific methyltransferase 2C,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,"GO:0051568//histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0035556//intracellular signal transduction",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0042800//histone methyltransferase activity (H3-K4 specific),K09188//Lysine degradation
58509,70,0,0,0,0,0,0,0,0,0,20,0,"CACTIN;cactin, spliceosome C complex subunit",GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0032720//negative regulation of tumor necrosis factor production;GO:0000398//mRNA splicing, via spliceosome;GO:0071347//cellular response to interleukin-1;GO:0001933//negative regulation of protein phosphorylation;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0032688//negative regulation of interferon-beta production;GO:0032717//negative regulation of interleukin-8 production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
58510,136,0,0,0,0,0,14,6,3,0,2,0,PRODH2;proline dehydrogenase (oxidase) 2,GO:0005743//mitochondrial inner membrane,GO:0010133//proline catabolic process to glutamate;GO:0055114//oxidation-reduction process,GO:0004657//proline dehydrogenase activity,K11394//Metabolic pathways;Arginine and proline metabolism
58511,0,0,0,0,11,0,0,0,0,0,0,0,DNASE2B;deoxyribonuclease II beta,GO:0005576//extracellular region;GO:0005622//intracellular;GO:0005764//lysosome,GO:0006309//apoptotic DNA fragmentation,GO:0004531//deoxyribonuclease II activity,K01158//Lysosome
58512,0,0,0,0,0,5,0,1,20,0,0,0,"DLGAP3;discs, large (Drosophila) homolog-associated protein 3",GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0007267//cell-cell signaling,GO:0001540//beta-amyloid binding;GO:0005515//protein binding,K15008//Glutamatergic synapse
58513,70,1,0,1,20,26,57,32,52,0,0,251,EPS15L1;epidermal growth factor receptor pathway substrate 15-like 1,GO:0030132//clathrin coat of coated pit;GO:0005634//nucleus;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006897//endocytosis;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005509//calcium ion binding;GO:0005515//protein binding,K12472//Endocytosis
58515,0,2,3,19,94,0,0,58,0,0,0,0,SELK;selenoprotein K,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:2000406//positive regulation of T cell migration;GO:0042102//positive regulation of T cell proliferation;GO:0018345//protein palmitoylation;GO:0045728//respiratory burst after phagocytosis;GO:0051223//regulation of protein transport;GO:0006979//response to oxidative stress;GO:0006816//calcium ion transport;GO:0010742//macrophage derived foam cell differentiation,-,-
58516,0,0,2,9,39,0,0,1,12,0,1,479,"FAM60A;family with sequence similarity 60, member A",GO:0016580//Sin3 complex,GO:0030336//negative regulation of cell migration,GO:0005515//protein binding,K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
58517,0,24,0,20,78,27,26,0,21,292,10,0,RBM25;RNA binding motif protein 25,GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0042981//regulation of apoptotic process;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding,K12822//Spliceosome
58524,0,0,0,0,0,0,20,0,0,0,0,0,DMRT3;doublesex and mab-3 related transcription factor 3,GO:0005634//nucleus,"GO:0046661//male sex differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007548//sex differentiation;GO:0019226//transmission of nerve impulse;GO:0006351//transcription, DNA-templated;GO:0007628//adult walking behavior;GO:0021521//ventral spinal cord interneuron specification;GO:0042487//regulation of odontogenesis of dentin-containing tooth",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
58525,0,0,0,0,0,0,0,0,61,0,0,0,WIZ;widely interspaced zinc finger motifs,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0070208//protein heterotrimerization;GO:0050821//protein stabilization;GO:0010571//positive regulation of nuclear cell cycle DNA replication,GO:0005515//protein binding;GO:0046872//metal ion binding,-
58526,14,0,0,0,0,0,15,19,0,148,0,0,MID1IP1;MID1 interacting protein 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule,GO:0051351//positive regulation of ligase activity;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0007026//negative regulation of microtubule depolymerization;GO:0051258//protein polymerization;GO:0006629//lipid metabolic process,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
58527,0,20,0,28,14,0,0,0,0,0,0,0,ABRACL;ABRA C-terminal like,-,-,-,-
58528,0,45,1,61,184,22,0,56,82,0,4,0,RRAGD;Ras-related GTP binding D,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0032008//positive regulation of TOR signaling;GO:0034613//cellular protein localization;GO:0071230//cellular response to amino acid stimulus,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005525//GTP binding,-
58529,0,0,0,0,0,19,0,0,47,0,0,0,MYOZ1;myozenin 1,GO:0015629//actin cytoskeleton;GO:0031143//pseudopodium;GO:0005634//nucleus,GO:0030239//myofibril assembly,GO:0005515//protein binding;GO:0051373//FATZ binding,-
58531,0,0,0,0,0,0,0,3,0,0,9,0,PRM3;protamine 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000786//nucleosome,GO:0030317//sperm motility;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0030261//chromosome condensation;GO:0030154//cell differentiation,GO:0003677//DNA binding,-
58533,0,1,0,21,56,0,0,0,48,0,0,0,SNX6;sorting nexin 6,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031901//early endosome membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005622//intracellular,"GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0035091//phosphatidylinositol binding,-
58538,36,0,0,0,0,0,8,0,17,0,0,0,"MPP4;membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)",GO:0042734//presynaptic membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035418//protein localization to synapse,-,K00942//Purine metabolism;Metabolic pathways
5858,0,0,0,0,0,54,52,0,88,0,9,0,PZP;pregnancy-zone protein,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,GO:0010951//negative regulation of endopeptidase activity;GO:0007565//female pregnancy,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity,K03910//Complement and coagulation cascades
5859,0,59,1,4,32,26,0,0,46,0,8,0,QARS;glutaminyl-tRNA synthetase,GO:0005829//cytosol;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0007420//brain development;GO:0006418//tRNA aminoacylation for protein translation;GO:0006425//glutaminyl-tRNA aminoacylation;GO:0010467//gene expression,GO:0005524//ATP binding;GO:0004819//glutamine-tRNA ligase activity;GO:0005515//protein binding,K01886//ABC transporters;Aminoacyl-tRNA biosynthesis;Metabolic pathways;Ribosome
586,0,0,0,0,0,31,0,0,47,0,9,0,"BCAT1;branched chain amino-acid transaminase 1, cytosolic",GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0000082//G1/S transition of mitotic cell cycle;GO:0009083//branched-chain amino acid catabolic process;GO:0008283//cell proliferation;GO:0009082//branched-chain amino acid biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process,GO:0052654//L-leucine transaminase activity;GO:0042802//identical protein binding;GO:0052656//L-isoleucine transaminase activity;GO:0052655//L-valine transaminase activity,"K00826//Valine, leucine and isoleucine degradation;Valine, leucine and isoleucine biosynthesis;Metabolic pathways;Glucosinolate biosynthesis;Pantothenate and CoA biosynthesis;Biosynthesis of secondary metabolites;Ribosome;Folate biosynthesis"
5860,0,24,0,20,109,30,31,0,2,0,0,0,QDPR;quinoid dihydropteridine reductase,GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0010288//response to lead ion;GO:0034641//cellular nitrogen compound metabolic process;GO:0010044//response to aluminum ion;GO:0006520//cellular amino acid metabolic process;GO:0035690//cellular response to drug;GO:0055114//oxidation-reduction process;GO:0033762//response to glucagon;GO:0051066//dihydrobiopterin metabolic process;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0044281//small molecule metabolic process;GO:0001889//liver development;GO:0006559//L-phenylalanine catabolic process,"GO:0004155//6,7-dihydropteridine reductase activity;GO:0070404//NADH binding;GO:0042803//protein homodimerization activity;GO:0070402//NADPH binding;GO:0009055//electron carrier activity",K00357//Metabolic pathways;Folate biosynthesis
5861,0,1,0,33,183,25,19,54,30,0,0,506,"RAB1A;RAB1A, member RAS oncogene family",GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005829//cytosol;GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane,GO:0072606//interleukin-8 secretion;GO:0006184//GTP catabolic process;GO:0042742//defense response to bacterium;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006914//autophagy;GO:0006897//endocytosis;GO:0000278//mitotic cell cycle;GO:0007030//Golgi organization;GO:0047496//vesicle transport along microtubule;GO:0019068//virion assembly;GO:0042384//cilium assembly;GO:0016477//cell migration;GO:0000045//autophagic vacuole assembly;GO:0032402//melanosome transport;GO:0034446//substrate adhesion-dependent cell spreading;GO:0030252//growth hormone secretion,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,K07874//Legionellosis
5862,0,7,2,109,193,0,36,0,36,99,0,0,"RAB2A;RAB2A, member RAS oncogene family",GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005765//lysosomal membrane;GO:0000139//Golgi membrane;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0015031//protein transport;GO:0007030//Golgi organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0000278//mitotic cell cycle,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0019003//GDP binding,-
5863,1,0,1,0,0,2,0,0,1,0,2,0,RGL2;ral guanine nucleotide dissociation stimulator-like 2,GO:0005622//intracellular,GO:0032320//positive regulation of Ras GTPase activity;GO:0007265//Ras protein signal transduction,GO:0005088//Ras guanyl-nucleotide exchange factor activity,K08732//Pathways in cancer;Pancreatic cancer;Colorectal cancer
5864,0,0,0,0,0,0,0,0,18,0,7,0,"RAB3A;RAB3A, member RAS oncogene family",GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0031982//vesicle;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane;GO:0005829//cytosol;GO:0001669//acrosomal vesicle,GO:0007264//small GTPase mediated signal transduction;GO:0045054//constitutive secretory pathway;GO:0032781//positive regulation of ATPase activity;GO:0003016//respiratory system process;GO:0031630//regulation of synaptic vesicle fusion to presynaptic membrane;GO:0007409//axonogenesis;GO:0006184//GTP catabolic process;GO:0014047//glutamate secretion;GO:0051602//response to electrical stimulus;GO:0016188//synaptic vesicle maturation;GO:0015031//protein transport;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0048790//maintenance of presynaptic active zone structure;GO:0050975//sensory perception of touch;GO:0007274//neuromuscular synaptic transmission;GO:0007005//mitochondrion organization;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0009791//post-embryonic development;GO:0030324//lung development;GO:0007268//synaptic transmission;GO:0045921//positive regulation of exocytosis,GO:0005515//protein binding;GO:0001671//ATPase activator activity;GO:0051117//ATPase binding;GO:0003924//GTPase activity;GO:0051020//GTPase binding;GO:0005525//GTP binding;GO:0008022//protein C-terminus binding,K07882//Synaptic vesicle cycle
5865,147,407,5,442,1523,22,43,1,61,0,10,0,"RAB3B;RAB3B, member RAS oncogene family",GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0030141//secretory granule,GO:0007264//small GTPase mediated signal transduction;GO:0051586//positive regulation of dopamine uptake involved in synaptic transmission;GO:0097494//regulation of vesicle size;GO:0006184//GTP catabolic process;GO:0019882//antigen processing and presentation;GO:0017157//regulation of exocytosis;GO:0015031//protein transport;GO:0018125//peptidyl-cysteine methylation,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K06108//Tight junction
5866,84,0,0,0,0,8,0,0,0,105,0,0,RAB3IL1;RAB3A interacting protein (rabin3)-like 1,-,GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport,GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
5867,0,0,0,41,138,8,0,1,0,0,24,0,"RAB4A;RAB4A, member RAS oncogene family",GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0016020//membrane;GO:0031982//vesicle;GO:0048471//perinuclear region of cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0030100//regulation of endocytosis;GO:0006184//GTP catabolic process;GO:0019882//antigen processing and presentation;GO:0015031//protein transport;GO:0061024//membrane organization,GO:0008565//protein transporter activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019003//GDP binding;GO:0005515//protein binding,K07879//Endocytosis
5868,59,43,0,54,256,0,0,49,1,0,0,0,"RAB5A;RAB5A, member RAS oncogene family",GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0043195//terminal bouton;GO:0001726//ruffle;GO:0045121//membrane raft;GO:0042470//melanosome;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0045335//phagocytic vesicle;GO:0005737//cytoplasm,GO:0051036//regulation of endosome size;GO:0030154//cell differentiation;GO:2000300//regulation of synaptic vesicle exocytosis;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0045921//positive regulation of exocytosis;GO:0051489//regulation of filopodium assembly;GO:0015031//protein transport;GO:0007399//nervous system development;GO:0007596//blood coagulation;GO:0045022//early endosome to late endosome transport;GO:0006897//endocytosis;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0005515//protein binding,K07887//Amoebiasis;Tuberculosis;Amyotrophic lateral sclerosis (ALS);Vasopressin-regulated water reabsorption;Phagosome;Endocytosis
5869,0,63,0,27,140,3,0,0,44,0,16,4,"RAB5B;RAB5B, member RAS oncogene family",GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0005622//intracellular;GO:0042470//melanosome;GO:0016020//membrane;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0048227//plasma membrane to endosome transport;GO:0007264//small GTPase mediated signal transduction;GO:0030100//regulation of endocytosis;GO:0006184//GTP catabolic process;GO:0019882//antigen processing and presentation;GO:0007032//endosome organization;GO:0015031//protein transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding,K07888//Tuberculosis;Amoebiasis;Endocytosis;Phagosome;Vasopressin-regulated water reabsorption
587,0,41,0,0,2,0,58,0,14,0,9,0,"BCAT2;branched chain amino-acid transaminase 2, mitochondrial",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0034641//cellular nitrogen compound metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0009082//branched-chain amino acid biosynthetic process;GO:0006573//valine metabolic process;GO:0044281//small molecule metabolic process;GO:0010817//regulation of hormone levels;GO:0006550//isoleucine catabolic process;GO:0006551//leucine metabolic process,GO:0052655//L-valine transaminase activity;GO:0052656//L-isoleucine transaminase activity;GO:0052654//L-leucine transaminase activity,"K00826//Folate biosynthesis;Ribosome;Biosynthesis of secondary metabolites;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Valine, leucine and isoleucine degradation;Glucosinolate biosynthesis;Pantothenate and CoA biosynthesis"
5870,0,136,2,77,327,8,69,0,0,2,30,0,"RAB6A;RAB6A, member RAS oncogene family",GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0007264//small GTPase mediated signal transduction;GO:0018125//peptidyl-cysteine methylation;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0034498//early endosome to Golgi transport;GO:0019882//antigen processing and presentation;GO:0000042//protein targeting to Golgi;GO:0034067//protein localization to Golgi apparatus;GO:0006184//GTP catabolic process",GO:0005515//protein binding;GO:0019904//protein domain specific binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
5871,64,0,0,5,0,0,23,42,46,287,0,0,MAP4K2;mitogen-activated protein kinase kinase kinase kinase 2,GO:0000139//Golgi membrane;GO:0016323//basolateral plasma membrane,GO:0046330//positive regulation of JNK cascade;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0006955//immune response;GO:0007257//activation of JUN kinase activity;GO:0007254//JNK cascade;GO:0045087//innate immune response;GO:0006903//vesicle targeting,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005083//small GTPase regulator activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005524//ATP binding,K04414//MAPK signaling pathway
5872,0,1,0,59,79,0,17,0,16,0,1,0,"RAB13;RAB13, member RAS oncogene family",GO:0005802//trans-Golgi network;GO:0031410//cytoplasmic vesicle;GO:0030027//lamellipodium;GO:0030659//cytoplasmic vesicle membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0032593//insulin-responsive compartment;GO:0055037//recycling endosome;GO:0030139//endocytic vesicle;GO:0005923//tight junction;GO:0055038//recycling endosome membrane;GO:0030658//transport vesicle membrane;GO:0016328//lateral plasma membrane;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome,GO:0006184//GTP catabolic process;GO:1902463//protein localization to cell leading edge;GO:0032869//cellular response to insulin stimulus;GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0044795//trans-Golgi network to recycling endosome transport;GO:0031175//neuron projection development;GO:0030866//cortical actin cytoskeleton organization;GO:0097368//establishment of Sertoli cell barrier;GO:0061024//membrane organization;GO:0035767//endothelial cell chemotaxis;GO:0016197//endosomal transport;GO:0090002//establishment of protein localization to plasma membrane;GO:0032456//endocytic recycling;GO:0010737//protein kinase A signaling;GO:0070830//tight junction assembly,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0034236//protein kinase A catalytic subunit binding,K06109//Tight junction
5873,0,238,36,301,365,32,8,0,0,3,0,0,"RAB27A;RAB27A, member RAS oncogene family",GO:0001750//photoreceptor outer segment;GO:0016324//apical plasma membrane;GO:0005770//late endosome;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0032585//multivesicular body membrane;GO:0005794//Golgi apparatus;GO:0070382//exocytic vesicle;GO:0005764//lysosome;GO:0030667//secretory granule membrane,GO:0019882//antigen processing and presentation;GO:0006184//GTP catabolic process;GO:0043316//cytotoxic T cell degranulation;GO:0010628//positive regulation of gene expression;GO:0048489//synaptic vesicle transport;GO:0006605//protein targeting;GO:1990182//exosomal secretion;GO:0043320//natural killer cell degranulation;GO:0007264//small GTPase mediated signal transduction;GO:0007596//blood coagulation;GO:0006887//exocytosis;GO:0045921//positive regulation of exocytosis;GO:0044267//cellular protein metabolic process;GO:0032402//melanosome transport;GO:0030318//melanocyte differentiation;GO:0071985//multivesicular body sorting pathway,GO:0031489//myosin V binding;GO:0019904//protein domain specific binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0019003//GDP binding,-
5874,1,166,4,152,558,0,15,121,48,0,1,0,"RAB27B;RAB27B, member RAS oncogene family",GO:0030140//trans-Golgi network transport vesicle;GO:0070062//extracellular vesicular exosome;GO:0042589//zymogen granule membrane;GO:0005795//Golgi stack;GO:0032585//multivesicular body membrane;GO:0016324//apical plasma membrane,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport;GO:0071985//multivesicular body sorting pathway,GO:0019003//GDP binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019904//protein domain specific binding,K07886//Pancreatic secretion
5875,0,1,1,1,2,0,0,0,0,0,1,0,"RABGGTA;Rab geranylgeranyltransferase, alpha subunit",GO:0005968//Rab-protein geranylgeranyltransferase complex,GO:0006464//cellular protein modification process;GO:0007601//visual perception;GO:0018344//protein geranylgeranylation,GO:0008270//zinc ion binding;GO:0004663//Rab geranylgeranyltransferase activity;GO:0017137//Rab GTPase binding,-
5876,2,0,1,24,80,46,0,0,7,0,0,0,"RABGGTB;Rab geranylgeranyltransferase, beta subunit",GO:0005968//Rab-protein geranylgeranyltransferase complex,GO:0018344//protein geranylgeranylation;GO:0007601//visual perception;GO:0006464//cellular protein modification process,GO:0017137//Rab GTPase binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004663//Rab geranylgeranyltransferase activity,-
5877,0,1,0,32,54,0,0,212,3,0,0,0,RABIF;RAB interacting factor,-,GO:0015031//protein transport;GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0061025//membrane fusion,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K01489//Drug metabolism - other enzymes;Pyrimidine metabolism;Metabolic pathways
5878,0,1,0,2,19,10,32,50,0,0,2,0,"RAB5C;RAB5C, member RAS oncogene family",GO:0031901//early endosome membrane;GO:0030139//endocytic vesicle;GO:0043231//intracellular membrane-bounded organelle;GO:0005765//lysosomal membrane;GO:0042470//melanosome;GO:0005811//lipid particle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0030100//regulation of endocytosis;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0048227//plasma membrane to endosome transport;GO:0015031//protein transport;GO:0007032//endosome organization,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07889//Endocytosis;Vasopressin-regulated water reabsorption;Phagosome;Amoebiasis;Tuberculosis
5879,0,1,1,65,417,15,0,0,15,0,0,1,"RAC1;ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)",GO:0005802//trans-Golgi network;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0001891//phagocytic cup;GO:0019897//extrinsic component of plasma membrane;GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0005829//cytosol,"GO:0051496//positive regulation of stress fiber assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0006954//inflammatory response;GO:0007160//cell-matrix adhesion;GO:0045740//positive regulation of DNA replication;GO:0006928//cellular component movement;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0010592//positive regulation of lamellipodium assembly;GO:0045453//bone resorption;GO:0010310//regulation of hydrogen peroxide metabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0031295//T cell costimulation;GO:0031529//ruffle organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0002093//auditory receptor cell morphogenesis;GO:0043652//engulfment of apoptotic cell;GO:0045216//cell-cell junction organization;GO:0051894//positive regulation of focal adhesion assembly;GO:0006972//hyperosmotic response;GO:0072659//protein localization to plasma membrane;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0009653//anatomical structure morphogenesis;GO:0006184//GTP catabolic process;GO:0030036//actin cytoskeleton organization;GO:0071526//semaphorin-plexin signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0007411//axon guidance;GO:0016032//viral process;GO:0097178//ruffle assembly;GO:0030168//platelet activation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0002551//mast cell chemotaxis;GO:0051668//localization within membrane;GO:0009611//response to wounding;GO:0030334//regulation of cell migration;GO:0021831//embryonic olfactory bulb interneuron precursor migration;GO:0090103//cochlea morphogenesis;GO:0007596//blood coagulation;GO:0048532//anatomical structure arrangement;GO:0007155//cell adhesion;GO:0001934//positive regulation of protein phosphorylation;GO:0097190//apoptotic signaling pathway;GO:0048870//cell motility;GO:0050690//regulation of defense response to virus by virus;GO:0030032//lamellipodium assembly;GO:0045087//innate immune response;GO:0060263//regulation of respiratory burst;GO:0007264//small GTPase mediated signal transduction;GO:0071542//dopaminergic neuron differentiation;GO:0021799//cerebral cortex radially oriented cell migration;GO:0030041//actin filament polymerization;GO:0008283//cell proliferation;GO:0003382//epithelial cell morphogenesis;GO:0048813//dendrite morphogenesis;GO:0035025//positive regulation of Rho protein signal transduction;GO:0032707//negative regulation of interleukin-23 production;GO:0035556//intracellular signal transduction",GO:0017137//Rab GTPase binding;GO:0019899//enzyme binding;GO:0005525//GTP binding;GO:0019901//protein kinase binding;GO:0031996//thioesterase binding;GO:0003924//GTPase activity;GO:0051022//Rho GDP-dissociation inhibitor binding;GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding,K04392//Adherens junction;Renal cell carcinoma;Colorectal cancer;Epithelial cell signaling in Helicobacter pylori infection;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Viral myocarditis;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Pancreatic secretion;Toll-like receptor signaling pathway;Axon guidance;Chemokine signaling pathway;Pathways in cancer;Salmonella infection;Pancreatic cancer;Phagosome;Focal adhesion;VEGF signaling pathway;Osteoclast differentiation;Neurotrophin signaling pathway;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Shigellosis;Leukocyte transendothelial migration;B cell receptor signaling pathway;Fc epsilon RI signaling pathway;Bacterial invasion of epithelial cells
5881,0,0,0,0,0,0,11,0,0,0,1,0,"RAC3;ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)",GO:0031941//filamentous actin;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0012505//endomembrane system;GO:0030027//lamellipodium;GO:0030426//growth cone;GO:0043025//neuronal cell body,GO:0035556//intracellular signal transduction;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0050885//neuromuscular process controlling balance;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0006184//GTP catabolic process;GO:0030036//actin cytoskeleton organization;GO:0030031//cell projection assembly;GO:0031175//neuron projection development;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0048306//calcium-dependent protein binding;GO:0005515//protein binding,K07861//Pancreatic cancer;Fc epsilon RI signaling pathway;Axon guidance;Pathways in cancer;B cell receptor signaling pathway;Regulation of actin cytoskeleton;Wnt signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Viral myocarditis;VEGF signaling pathway;Focal adhesion;Colorectal cancer;Adherens junction
5883,0,1086,662,687,1806,0,0,645,38,239,1847,27,RAD9A;RAD9 homolog A (S. pombe),GO:0030896//checkpoint clamp complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006260//DNA replication;GO:0000738//DNA catabolic process, exonucleolytic;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0071479//cellular response to ionizing radiation;GO:0000077//DNA damage checkpoint;GO:0006974//cellular response to DNA damage stimulus;GO:0000076//DNA replication checkpoint;GO:0031573//intra-S DNA damage checkpoint",GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0008853//exodeoxyribonuclease III activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0008408//3'-5' exonuclease activity;GO:0017124//SH3 domain binding,-
5884,0,23,0,91,50,11,0,147,26,107,39,0,RAD17;RAD17 homolog (S. pombe),"GO:0005730//nucleolus;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0005634//nucleus",GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0008156//negative regulation of DNA replication;GO:0000077//DNA damage checkpoint;GO:0006974//cellular response to DNA damage stimulus;GO:0042325//regulation of phosphorylation;GO:0000076//DNA replication checkpoint;GO:0007093//mitotic cell cycle checkpoint,GO:0005524//ATP binding;GO:0005515//protein binding,K06662//Meiosis - yeast;Cell cycle - yeast
5885,0,85,1,42,146,40,6,0,37,0,10,0,RAD21;RAD21 homolog (S. pombe),"GO:0034991//nuclear meiotic cohesin complex;GO:0005654//nucleoplasm;GO:0008278//cohesin complex;GO:0016020//membrane;GO:0005694//chromosome;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus",GO:0071168//protein localization to chromatin;GO:0006915//apoptotic process;GO:0007131//reciprocal meiotic recombination;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0007067//mitotic nuclear division;GO:0006310//DNA recombination;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006302//double-strand break repair,GO:0005515//protein binding,K06670//Cell cycle;Cell cycle - yeast
5886,0,108,0,41,108,0,26,145,66,0,122,0,RAD23A;RAD23 homolog A (S. cerevisiae),GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006289//nucleotide-excision repair;GO:0016032//viral process;GO:0045070//positive regulation of viral genome replication;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0003684//damaged DNA binding;GO:1990381//ubiquitin-specific protease binding;GO:0005515//protein binding;GO:0031593//polyubiquitin binding;GO:0003697//single-stranded DNA binding,K10839//Nucleotide excision repair;Protein processing in endoplasmic reticulum
5887,0,33,0,104,162,2,0,0,1,0,0,0,RAD23B;RAD23 homolog B (S. cerevisiae),GO:0005730//nucleolus;GO:0071942//XPC complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0000502//proteasome complex,"GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007283//spermatogenesis;GO:0006281//DNA repair;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006289//nucleotide-excision repair;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:0000718//nucleotide-excision repair, DNA damage removal",GO:0005515//protein binding;GO:0031593//polyubiquitin binding;GO:0003697//single-stranded DNA binding;GO:0003684//damaged DNA binding,K10839//Protein processing in endoplasmic reticulum;Nucleotide excision repair
5888,11,0,0,0,0,34,0,0,18,67,0,0,RAD51;RAD51 recombinase,GO:0000228//nuclear chromosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0000793//condensed chromosome;GO:0005815//microtubule organizing center;GO:0000800//lateral element;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0000794//condensed nuclear chromosome;GO:0016605//PML body;GO:0005730//nucleolus,GO:0007131//reciprocal meiotic recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006974//cellular response to DNA damage stimulus;GO:0006268//DNA unwinding involved in DNA replication;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006200//ATP catabolic process;GO:0006310//DNA recombination;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0007126//meiotic nuclear division;GO:0006312//mitotic recombination;GO:0051106//positive regulation of DNA ligation;GO:0000730//DNA recombinase assembly;GO:0072757//cellular response to camptothecin;GO:0071479//cellular response to ionizing radiation;GO:0051260//protein homooligomerization,GO:0070182//DNA polymerase binding;GO:0043142//single-stranded DNA-dependent ATPase activity;GO:0042802//identical protein binding;GO:0003697//single-stranded DNA binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding,K04482//Pathways in cancer;Pancreatic cancer;Homologous recombination;Fanconi anemia pathway
5889,0,0,0,0,1,0,18,0,0,0,6,0,RAD51C;RAD51 paralog C,GO:0033065//Rad51C-XRCC3 complex;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0048476//Holliday junction resolvase complex;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0000724//double-strand break repair via homologous recombination;GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0007596//blood coagulation;GO:0000737//DNA catabolic process, endonucleolytic;GO:0007062//sister chromatid cohesion;GO:0006200//ATP catabolic process;GO:0007066//female meiosis sister chromatid cohesion;GO:0006310//DNA recombination;GO:0007141//male meiosis I;GO:0006281//DNA repair;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle",GO:0000400//four-way junction DNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0008094//DNA-dependent ATPase activity;GO:0005524//ATP binding,K10870//Homologous recombination;Fanconi anemia pathway
5890,0,0,0,6,0,0,14,0,36,0,0,0,RAD51B;RAD51 paralog B,GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0005634//nucleus;GO:0005657//replication fork;GO:0005654//nucleoplasm,GO:0007596//blood coagulation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0006200//ATP catabolic process;GO:0006310//DNA recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0007131//reciprocal meiotic recombination;GO:0006281//DNA repair,GO:0005515//protein binding;GO:0000400//four-way junction DNA binding;GO:0003697//single-stranded DNA binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity,K10869//Homologous recombination
5891,3,0,0,0,0,9,0,0,15,0,0,0,MOK;MOK protein kinase,GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle,GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity,-
5892,0,23,0,0,0,0,4,34,59,0,1,0,RAD51D;RAD51 paralog D,"GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005657//replication fork;GO:0005634//nucleus;GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex",GO:0000723//telomere maintenance;GO:0006281//DNA repair;GO:0007131//reciprocal meiotic recombination;GO:0042148//strand invasion;GO:0000724//double-strand break repair via homologous recombination;GO:0006200//ATP catabolic process,GO:0043015//gamma-tubulin binding;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0000400//four-way junction DNA binding;GO:0003697//single-stranded DNA binding,K10871//Homologous recombination
5893,0,0,0,0,0,0,21,0,103,0,2,0,RAD52;RAD52 homolog (S. cerevisiae),GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0000730//DNA recombinase assembly;GO:0000724//double-strand break repair via homologous recombination,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0003677//DNA binding,K10873//Homologous recombination
5894,132,41,37,31,111,0,0,0,12,0,71,0,"RAF1;Raf-1 proto-oncogene, serine/threonine kinase",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0031143//pseudopodium;GO:0005741//mitochondrial outer membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0034220//ion transmembrane transport;GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0007165//signal transduction;GO:2000145//regulation of cell motility;GO:0042060//wound healing;GO:0000165//MAPK cascade;GO:0007190//activation of adenylate cyclase activity;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0007411//axon guidance;GO:0055085//transmembrane transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045104//intermediate filament cytoskeleton organization;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0045595//regulation of cell differentiation;GO:0008286//insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035023//regulation of Rho protein signal transduction;GO:0035019//somatic stem cell maintenance;GO:0030168//platelet activation;GO:0031333//negative regulation of protein complex assembly;GO:0008283//cell proliferation;GO:0000186//activation of MAPKK activity;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007264//small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0071550//death-inducing signaling complex assembly;GO:0007265//Ras protein signal transduction;GO:0007507//heart development,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046982//protein heterodimerization activity;GO:0031267//small GTPase binding;GO:0004709//MAP kinase kinase kinase activity;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0005524//ATP binding,K04366//B cell receptor signaling pathway;Acute myeloid leukemia;Fc epsilon RI signaling pathway;Melanogenesis;Melanoma;Neurotrophin signaling pathway;Hepatitis C;Regulation of actin cytoskeleton;Non-small cell lung cancer;Progesterone-mediated oocyte maturation;Long-term potentiation;Prostate cancer;Tuberculosis;Insulin signaling pathway;Colorectal cancer;Vascular smooth muscle contraction;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Fc gamma R-mediated phagocytosis;Long-term depression;VEGF signaling pathway;Focal adhesion;Glioma;Endometrial cancer;Influenza A;Serotonergic synapse;Alcoholism;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Gap junction;Renal cell carcinoma;Bladder cancer;ErbB signaling pathway;MAPK signaling pathway
5896,0,0,0,0,0,0,107,0,0,0,0,0,RAG1;recombination activating gene 1,GO:0005634//nucleus,GO:0006955//immune response;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0002250//adaptive immune response;GO:0010390//histone monoubiquitination;GO:0002331//pre-B cell allelic exclusion;GO:0033077//T cell differentiation in thymus;GO:0030183//B cell differentiation;GO:0051865//protein autoubiquitination;GO:0033151//V(D)J recombination;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048538//thymus development;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0045580//regulation of T cell differentiation;GO:0043029//T cell homeostasis;GO:0006310//DNA recombination,GO:0008270//zinc ion binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0004519//endonuclease activity;GO:0042393//histone binding;GO:0042803//protein homodimerization activity;GO:0016881//acid-amino acid ligase activity;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,K10628//Primary immunodeficiency
5897,0,0,0,0,0,0,12,0,2,0,0,0,RAG2;recombination activating gene 2,GO:0005634//nucleus,GO:0002331//pre-B cell allelic exclusion;GO:0033151//V(D)J recombination;GO:0030183//B cell differentiation;GO:0016568//chromatin modification;GO:0033077//T cell differentiation in thymus,"GO:0008270//zinc ion binding;GO:0035091//phosphatidylinositol binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035064//methylated histone binding;GO:0003677//DNA binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0003682//chromatin binding",K10988//Primary immunodeficiency
5898,0,11,54,19,81,0,0,66,2,0,0,0,RALA;v-ral simian leukemia viral oncogene homolog A (ras related),GO:0030139//endocytic vesicle;GO:0030496//midbody;GO:0005925//focal adhesion;GO:0030659//cytoplasmic vesicle membrane;GO:0032154//cleavage furrow;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0051665//membrane raft localization;GO:0061024//membrane organization;GO:0031532//actin cytoskeleton reorganization;GO:0006887//exocytosis;GO:0017157//regulation of exocytosis;GO:0006935//chemotaxis;GO:0006184//GTP catabolic process;GO:0007265//Ras protein signal transduction;GO:0007165//signal transduction;GO:0051491//positive regulation of filopodium assembly;GO:0000910//cytokinesis;GO:0016032//viral process;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0031755//Edg-2 lysophosphatidic acid receptor binding,K07834//Pathways in cancer;Pancreatic cancer
58985,0,0,0,0,0,0,20,0,0,0,0,0,"IL22RA1;interleukin 22 receptor, alpha 1",GO:0016021//integral component of membrane,GO:0050829//defense response to Gram-negative bacterium;GO:0019221//cytokine-mediated signaling pathway,GO:0042015//interleukin-20 binding;GO:0004904//interferon receptor activity,K05138//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
58986,0,23,0,0,0,23,0,0,23,0,3,0,TMEM8A;transmembrane protein 8A,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005765//lysosomal membrane,GO:0007155//cell adhesion,-,K03006//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Herpes simplex infection;Huntington's disease;Metabolic pathways
5899,12,144,3,75,278,2,21,0,17,0,0,2,RALB;v-ral simian leukemia viral oncogene homolog B,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030496//midbody,GO:0006915//apoptotic process;GO:0001928//regulation of exocyst assembly;GO:0006184//GTP catabolic process;GO:0007265//Ras protein signal transduction;GO:0007165//signal transduction;GO:0060178//regulation of exocyst localization;GO:0000910//cytokinesis;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding,K07835//Pathways in cancer;Pancreatic cancer
59,0,0,0,0,10,27,18,0,22,0,26,0,"ACTA2;actin, alpha 2, smooth muscle, aorta",GO:0043234//protein complex;GO:0030485//smooth muscle contractile fiber;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0014829//vascular smooth muscle contraction;GO:0008217//regulation of blood pressure;GO:0072144//glomerular mesangial cell development;GO:0006936//muscle contraction;GO:0009615//response to virus,GO:0019901//protein kinase binding;GO:0005524//ATP binding,K12313//Vascular smooth muscle contraction
590,0,0,0,0,0,0,0,0,1,0,17,0,BCHE;butyrylcholinesterase,GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0016020//membrane;GO:0005641//nuclear envelope lumen;GO:0005615//extracellular space,"GO:0050805//negative regulation of synaptic transmission;GO:0019695//choline metabolic process;GO:0014016//neuroblast differentiation;GO:0044267//cellular protein metabolic process;GO:0007612//learning;GO:0008285//negative regulation of cell proliferation;GO:0051593//response to folic acid;GO:0043279//response to alkaloid;GO:0042493//response to drug;GO:0051384//response to glucocorticoid;GO:0007271//synaptic transmission, cholinergic;GO:0050783//cocaine metabolic process",GO:0033265//choline binding;GO:0042802//identical protein binding;GO:0003990//acetylcholinesterase activity;GO:0019899//enzyme binding;GO:0001540//beta-amyloid binding;GO:0004104//cholinesterase activity;GO:0003824//catalytic activity,-
5900,132,26,0,0,9,3,0,2,13,1,0,0,RALGDS;ral guanine nucleotide dissociation stimulator,GO:0005829//cytosol,GO:0007265//Ras protein signal transduction;GO:0050790//regulation of catalytic activity;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005083//small GTPase regulator activity;GO:0005515//protein binding,K08732//Pathways in cancer;Pancreatic cancer;Colorectal cancer
5901,0,22,0,9,34,0,0,0,0,0,0,0,"RAN;RAN, member RAS oncogene family",GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0000785//chromatin;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0016020//membrane,"GO:0006184//GTP catabolic process;GO:0032092//positive regulation of protein binding;GO:0030036//actin cytoskeleton organization;GO:0010467//gene expression;GO:0034629//cellular protein complex localization;GO:0007264//small GTPase mediated signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0019058//viral life cycle;GO:0000056//ribosomal small subunit export from nucleus;GO:0044281//small molecule metabolic process;GO:0006611//protein export from nucleus;GO:0075733//intracellular transport of virus;GO:0007052//mitotic spindle organization;GO:0006606//protein import into nucleus;GO:0016032//viral process;GO:0030521//androgen receptor signaling pathway;GO:0007067//mitotic nuclear division;GO:0006259//DNA metabolic process;GO:0007165//signal transduction;GO:0000055//ribosomal large subunit export from nucleus",GO:0050681//androgen receptor binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding,K07936//HTLV-I infection;RNA transport;Epstein-Barr virus infection;Ribosome biogenesis in eukaryotes
5902,1,169,78,44,118,0,0,408,58,0,348,0,RANBP1;RAN binding protein 1,GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0046604//positive regulation of mitotic centrosome separation;GO:0016032//viral process;GO:0046907//intracellular transport;GO:0007051//spindle organization;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0043547//positive regulation of GTPase activity,GO:0005092//GDP-dissociation inhibitor activity;GO:0005096//GTPase activator activity;GO:0008536//Ran GTPase binding,K15306//HTLV-I infection
5903,0,166,2,115,410,32,12,56,71,25,3,0,RANBP2;RAN binding protein 2,GO:0005643//nuclear pore;GO:0044615//nuclear pore nuclear basket;GO:0031965//nuclear membrane;GO:0042405//nuclear inclusion body;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0005975//carbohydrate metabolic process;GO:0006606//protein import into nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0010827//regulation of glucose transport;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0033132//negative regulation of glucokinase activity;GO:0016925//protein sumoylation;GO:0044281//small molecule metabolic process;GO:0000413//protein peptidyl-prolyl isomerization;GO:0051028//mRNA transport;GO:0055085//transmembrane transport;GO:0090526//regulation of gluconeogenesis involved in cellular glucose homeostasis;GO:0015758//glucose transport;GO:0006457//protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0008270//zinc ion binding;GO:0008536//Ran GTPase binding;GO:0003723//RNA binding,K12172//RNA transport
5905,0,14,2,18,22,33,86,1,54,152,7,0,RANGAP1;Ran GTPase activating protein 1,GO:0000922//spindle pole;GO:0005643//nuclear pore;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore,GO:0007165//signal transduction;GO:0046826//negative regulation of protein export from nucleus;GO:0000278//mitotic cell cycle;GO:0032853//positive regulation of Ran GTPase activity,GO:0005515//protein binding;GO:0005098//Ran GTPase activator activity,K14319//RNA transport
5906,0,0,0,44,45,0,2,0,29,0,0,0,"RAP1A;RAP1A, member of RAS oncogene family",GO:0032045//guanyl-nucleotide exchange factor complex;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0030054//cell junction;GO:0005770//late endosome;GO:0043005//neuron projection;GO:0005737//cytoplasm,GO:0071320//cellular response to cAMP;GO:0007596//blood coagulation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0006112//energy reserve metabolic process;GO:1990090//cellular response to nerve growth factor stimulus;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:0045860//positive regulation of protein kinase activity;GO:0010976//positive regulation of neuron projection development;GO:0030168//platelet activation;GO:2001214//positive regulation of vasculogenesis;GO:0032486//Rap protein signal transduction;GO:0007165//signal transduction;GO:0000186//activation of MAPKK activity;GO:0050796//regulation of insulin secretion;GO:0006184//GTP catabolic process;GO:0032854//positive regulation of Rap GTPase activity;GO:0015031//protein transport;GO:0038180//nerve growth factor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0061028//establishment of endothelial barrier;GO:0044281//small molecule metabolic process;GO:1901888//regulation of cell junction assembly,GO:0017016//Ras GTPase binding;GO:0005525//GTP binding;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0003924//GTPase activity;GO:0032403//protein complex binding;GO:0008565//protein transporter activity;GO:0005515//protein binding,K04353//MAPK signaling pathway;Neurotrophin signaling pathway;Focal adhesion;Renal cell carcinoma;Chemokine signaling pathway;Pancreatic secretion;Long-term potentiation;Leukocyte transendothelial migration
59067,0,0,0,0,0,19,0,0,0,0,0,0,IL21;interleukin 21,GO:0005615//extracellular space,GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0034105//positive regulation of tissue remodeling;GO:0006955//immune response;GO:0032733//positive regulation of interleukin-10 production;GO:0002729//positive regulation of natural killer cell cytokine production;GO:0030890//positive regulation of B cell proliferation;GO:0048469//cell maturation;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0050729//positive regulation of inflammatory response;GO:0007165//signal transduction;GO:0032740//positive regulation of interleukin-17 production;GO:0042102//positive regulation of T cell proliferation;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0032825//positive regulation of natural killer cell differentiation,GO:0005126//cytokine receptor binding;GO:0005134//interleukin-2 receptor binding;GO:0005125//cytokine activity,K05434//Jak-STAT signaling pathway;Cytokine-cytokine receptor interaction
5908,0,16,0,42,35,0,0,0,1,0,17,0,"RAP1B;RAP1B, member of RAS oncogene family",GO:0005622//intracellular;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0045121//membrane raft;GO:0005811//lipid particle;GO:0016020//membrane;GO:0005911//cell-cell junction,GO:0071320//cellular response to cAMP;GO:0007596//blood coagulation;GO:0008283//cell proliferation;GO:0006112//energy reserve metabolic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0050796//regulation of insulin secretion;GO:0006184//GTP catabolic process;GO:2000114//regulation of establishment of cell polarity;GO:0061028//establishment of endothelial barrier;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0030168//platelet activation;GO:0032486//Rap protein signal transduction;GO:1901888//regulation of cell junction assembly;GO:0044281//small molecule metabolic process,GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding;GO:0005515//protein binding,K07836//Chemokine signaling pathway;Pancreatic secretion;Leukocyte transendothelial migration;Long-term potentiation;MAPK signaling pathway;Neurotrophin signaling pathway;Renal cell carcinoma;Focal adhesion
59082,0,0,0,0,0,12,0,82,0,134,0,0,"CARD18;caspase recruitment domain family, member 18",-,GO:0010951//negative regulation of endopeptidase activity;GO:0006954//inflammatory response;GO:0042981//regulation of apoptotic process,GO:0004869//cysteine-type endopeptidase inhibitor activity,K01370//NOD-like receptor signaling pathway;Influenza A;Pertussis;Legionellosis;Cytosolic DNA-sensing pathway;Salmonella infection;Amyotrophic lateral sclerosis (ALS);K12806//NOD-like receptor signaling pathway
59084,60,43,0,12,10,0,0,0,37,0,0,194,ENPP5;ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative),GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007154//cell communication;GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,-
5909,62,42,0,7,18,52,0,0,22,0,0,0,RAP1GAP;RAP1 GTPase activating protein,GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol,GO:0006184//GTP catabolic process;GO:0032318//regulation of Ras GTPase activity;GO:0007165//signal transduction;GO:0032854//positive regulation of Rap GTPase activity,GO:0017016//Ras GTPase binding;GO:0003924//GTPase activity;GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046582//Rap GTPase activator activity,K08013//Leukocyte transendothelial migration;K04851//GnRH signaling pathway;Dopaminergic synapse;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Carbohydrate digestion and absorption;Serotonergic synapse;Vascular smooth muscle contraction;Glutamatergic synapse;Amphetamine addiction;MAPK signaling pathway;Type II diabetes mellitus;Cholinergic synapse;GABAergic synapse;Cardiac muscle contraction;Dilated cardiomyopathy;Calcium signaling pathway;Retrograde endocannabinoid signaling;Alzheimer's disease;Hypertrophic cardiomyopathy (HCM)
5910,0,0,0,30,15,0,1,1,56,0,0,0,"RAP1GDS1;RAP1, GTP-GDP dissociation stimulator 1",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0031034//myosin filament assembly;GO:0014829//vascular smooth muscle contraction;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0032321//positive regulation of Rho GTPase activity,GO:0005096//GTPase activator activity,K15042//Influenza A;K15043//Influenza A
5911,0,14,0,0,32,18,0,55,43,0,0,0,"RAP2A;RAP2A, member of RAS oncogene family",GO:0005829//cytosol;GO:0030496//midbody;GO:0070062//extracellular vesicular exosome;GO:0055038//recycling endosome membrane;GO:0055037//recycling endosome,GO:0032486//Rap protein signal transduction;GO:0034613//cellular protein localization;GO:0045184//establishment of protein localization;GO:0048814//regulation of dendrite morphogenesis;GO:0031954//positive regulation of protein autophosphorylation;GO:0006184//GTP catabolic process;GO:0030336//negative regulation of cell migration;GO:0046328//regulation of JNK cascade;GO:0031532//actin cytoskeleton reorganization,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,-
5912,0,0,1,0,23,7,54,6,57,0,0,0,"RAP2B;RAP2B, member of RAS oncogene family",GO:0005829//cytosol;GO:0045121//membrane raft;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0055038//recycling endosome membrane,GO:0007165//signal transduction;GO:0030168//platelet activation;GO:0032486//Rap protein signal transduction;GO:0006184//GTP catabolic process;GO:0031954//positive regulation of protein autophosphorylation;GO:0061097//regulation of protein tyrosine kinase activity;GO:0030336//negative regulation of cell migration;GO:0070527//platelet aggregation,GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0019003//GDP binding,-
5913,0,0,0,0,0,14,14,0,0,243,0,0,RAPSN;receptor-associated protein of the synapse,GO:0045211//postsynaptic membrane;GO:0005794//Golgi apparatus;GO:0031594//neuromuscular junction;GO:0030054//cell junction;GO:0005856//cytoskeleton,"GO:0043525//positive regulation of neuron apoptotic process;GO:0007271//synaptic transmission, cholinergic;GO:0007268//synaptic transmission",GO:0008270//zinc ion binding;GO:0033130//acetylcholine receptor binding;GO:0035255//ionotropic glutamate receptor binding,K15839//Cocaine addiction
5914,0,15,0,0,3,0,29,67,14,0,11,245,"RARA;retinoic acid receptor, alpha",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0009986//cell surface;GO:0030425//dendrite;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0048471//perinuclear region of cytoplasm,"GO:0043401//steroid hormone mediated signaling pathway;GO:0071300//cellular response to retinoic acid;GO:0032720//negative regulation of tumor necrosis factor production;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0003417//growth plate cartilage development;GO:0007283//spermatogenesis;GO:0045787//positive regulation of cell cycle;GO:0060010//Sertoli cell fate commitment;GO:0045666//positive regulation of neuron differentiation;GO:0032355//response to estradiol;GO:0071222//cellular response to lipopolysaccharide;GO:0033189//response to vitamin A;GO:0001843//neural tube closure;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0031641//regulation of myelination;GO:0030850//prostate gland development;GO:0060324//face development;GO:0048384//retinoic acid receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0007565//female pregnancy;GO:0032736//positive regulation of interleukin-13 production;GO:0032689//negative regulation of interferon-gamma production;GO:0001889//liver development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0034097//response to cytokine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006468//protein phosphorylation;GO:0031076//embryonic camera-type eye development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003148//outflow tract septum morphogenesis;GO:0032526//response to retinoic acid;GO:0045947//negative regulation of translational initiation;GO:0007165//signal transduction;GO:0001657//ureteric bud development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0051099//positive regulation of binding;GO:0060591//chondroblast differentiation;GO:0035264//multicellular organism growth;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0045471//response to ethanol;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0043277//apoptotic cell clearance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061037//negative regulation of cartilage development;GO:0060173//limb development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032753//positive regulation of interleukin-4 production;GO:0007281//germ cell development;GO:0030853//negative regulation of granulocyte differentiation;GO:0071391//cellular response to estrogen stimulus;GO:0060534//trachea cartilage development;GO:0032754//positive regulation of interleukin-5 production","GO:0005102//receptor binding;GO:0043422//protein kinase B binding;GO:0003707//steroid hormone receptor activity;GO:0003708//retinoic acid receptor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0003713//transcription coactivator activity;GO:0001972//retinoic acid binding;GO:0008144//drug binding;GO:0044323//retinoic acid-responsive element binding;GO:0031490//chromatin DNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0051018//protein kinase A binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0008270//zinc ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0000900//translation repressor activity, nucleic acid binding",K08527//Transcriptional misregulation in cancer;Pathways in cancer;Acute myeloid leukemia
5915,0,0,0,19,16,0,55,0,47,0,19,0,"RARB;retinoic acid receptor, beta",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0043401//steroid hormone mediated signaling pathway;GO:0021756//striatum development;GO:0048048//embryonic eye morphogenesis;GO:0048566//embryonic digestive tract development;GO:0003417//growth plate cartilage development;GO:0043065//positive regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003148//outflow tract septum morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0007165//signal transduction;GO:0001657//ureteric bud development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0035264//multicellular organism growth;GO:0031641//regulation of myelination;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0061037//negative regulation of cartilage development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048384//retinoic acid receptor signaling pathway;GO:0003406//retinal pigment epithelium development;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0035116//embryonic hindlimb morphogenesis,GO:0005515//protein binding;GO:0003708//retinoic acid receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0046965//retinoid X receptor binding;GO:0003677//DNA binding;GO:0008144//drug binding;GO:0032403//protein complex binding,K08528//Small cell lung cancer;Non-small cell lung cancer;Pathways in cancer
5916,0,0,0,0,0,0,0,0,11,0,0,0,"RARG;retinoic acid receptor, gamma",GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0016021//integral component of membrane;GO:0005730//nucleolus,GO:0071300//cellular response to retinoic acid;GO:0060740//prostate gland epithelium morphogenesis;GO:0043401//steroid hormone mediated signaling pathway;GO:0043068//positive regulation of programmed cell death;GO:0048048//embryonic eye morphogenesis;GO:0003430//growth plate cartilage chondrocyte growth;GO:0043065//positive regulation of apoptotic process;GO:0031076//embryonic camera-type eye development;GO:0070384//Harderian gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0032526//response to retinoic acid;GO:0001843//neural tube closure;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0060070//canonical Wnt signaling pathway;GO:0035264//multicellular organism growth;GO:0031641//regulation of myelination;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061037//negative regulation of cartilage development;GO:0060324//face development;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048384//retinoic acid receptor signaling pathway;GO:0003406//retinal pigment epithelium development;GO:0008284//positive regulation of cell proliferation;GO:0008361//regulation of cell size;GO:0035116//embryonic hindlimb morphogenesis;GO:0060534//trachea cartilage development,GO:0003677//DNA binding;GO:0046965//retinoid X receptor binding;GO:0003708//retinoic acid receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
5917,0,53,0,22,113,0,0,0,42,279,9,0,RARS;arginyl-tRNA synthetase,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex,GO:0006420//arginyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0005515//protein binding;GO:0034618//arginine binding;GO:0004814//arginine-tRNA ligase activity;GO:0005524//ATP binding;GO:0000049//tRNA binding,K01887//Aminoacyl-tRNA biosynthesis
5918,0,2,0,6,9,0,0,0,0,0,18,0,RARRES1;retinoic acid receptor responder (tazarotene induced) 1,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0008285//negative regulation of cell proliferation,-,-
5920,0,0,0,5,0,0,1,0,39,0,8,0,RARRES3;retinoic acid receptor responder (tazarotene induced) 3,GO:0016021//integral component of membrane,GO:0006644//phospholipid metabolic process;GO:0016042//lipid catabolic process;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding;GO:0004623//phospholipase A2 activity,K00678//Retinol metabolism;Vitamin digestion and absorption
5921,92,1,2,39,104,19,19,0,25,0,2,20,RASA1;RAS p21 protein activator (GTPase activating protein) 1,GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005829//cytosol,GO:0008360//regulation of cell shape;GO:0035556//intracellular signal transduction;GO:0007162//negative regulation of cell adhesion;GO:0051252//regulation of RNA metabolic process;GO:0032320//positive regulation of Ras GTPase activity;GO:0001570//vasculogenesis;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007165//signal transduction;GO:0043524//negative regulation of neuron apoptotic process;GO:0009790//embryo development;GO:0030833//regulation of actin filament polymerization;GO:0048514//blood vessel morphogenesis;GO:0000281//mitotic cytokinesis;GO:0001953//negative regulation of cell-matrix adhesion,GO:0005099//Ras GTPase activator activity;GO:0051020//GTPase binding;GO:0019870//potassium channel inhibitor activity;GO:0005102//receptor binding;GO:0001948//glycoprotein binding;GO:0005515//protein binding,K04352//MAPK signaling pathway;Axon guidance
5922,0,5,0,12,24,0,36,0,54,261,11,0,RASA2;RAS p21 protein activator 2,GO:0005737//cytoplasm;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0048471//perinuclear region of cytoplasm,GO:0035556//intracellular signal transduction;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007165//signal transduction;GO:0032320//positive regulation of Ras GTPase activity,GO:0005099//Ras GTPase activator activity;GO:0046872//metal ion binding,K08053//MAPK signaling pathway
5923,85,0,0,0,0,0,27,1,113,130,36,0,RASGRF1;Ras protein-specific guanine nucleotide-releasing factor 1,GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030426//growth cone,GO:0048167//regulation of synaptic plasticity;GO:0008283//cell proliferation;GO:0032320//positive regulation of Ras GTPase activity;GO:0007268//synaptic transmission;GO:0048168//regulation of neuronal synaptic plasticity;GO:0032863//activation of Rac GTPase activity;GO:0046578//regulation of Ras protein signal transduction;GO:0007616//long-term memory;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0031175//neuron projection development;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:0007165//signal transduction;GO:0035020//regulation of Rac protein signal transduction,GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0035254//glutamate receptor binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K04349//MAPK signaling pathway;Focal adhesion
5924,0,0,24,16,1,0,22,79,90,43,4,610,RASGRF2;Ras protein-specific guanine nucleotide-releasing factor 2,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0007268//synaptic transmission;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005516//calmodulin binding,K12326//MAPK signaling pathway
5925,0,0,0,60,54,9,0,60,72,0,0,0,RB1;retinoblastoma 1,GO:0035189//Rb-E2F complex;GO:0016605//PML body;GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005819//spindle;GO:0016514//SWI/SNF complex;GO:0005634//nucleus,"GO:0043353//enucleate erythrocyte differentiation;GO:0031175//neuron projection development;GO:0006469//negative regulation of protein kinase activity;GO:0045651//positive regulation of macrophage differentiation;GO:0071922//regulation of cohesin localization to chromatin;GO:0043550//regulation of lipid kinase activity;GO:0090230//regulation of centromere complex assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045879//negative regulation of smoothened signaling pathway;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0007070//negative regulation of transcription from RNA polymerase II promoter during mitosis;GO:0051402//neuron apoptotic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0042551//neuron maturation;GO:0045445//myoblast differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0007346//regulation of mitotic cell cycle;GO:0031134//sister chromatid biorientation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030521//androgen receptor signaling pathway;GO:0071459//protein localization to chromosome, centromeric region;GO:0000278//mitotic cell cycle;GO:0071930//negative regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048565//digestive tract development;GO:0007265//Ras protein signal transduction;GO:0000075//cell cycle checkpoint;GO:0034088//maintenance of mitotic sister chromatid cohesion;GO:0007093//mitotic cell cycle checkpoint;GO:0035914//skeletal muscle cell differentiation;GO:0034349//glial cell apoptotic process;GO:0006351//transcription, DNA-templated;GO:0097284//hepatocyte apoptotic process;GO:0007050//cell cycle arrest;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0051146//striated muscle cell differentiation;GO:0006338//chromatin remodeling",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0051219//phosphoprotein binding;GO:0008134//transcription factor binding;GO:0019900//kinase binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0050681//androgen receptor binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0003677//DNA binding;GO:0001047//core promoter binding;GO:0003713//transcription coactivator activity,K06618//Pancreatic cancer;HTLV-I infection;Pathways in cancer;Small cell lung cancer;Prostate cancer;Melanoma;Chronic myeloid leukemia;Non-small cell lung cancer;Epstein-Barr virus infection;Cell cycle;Bladder cancer;Glioma
5926,0,0,0,0,37,0,23,0,40,0,19,0,ARID4A;AT rich interactive domain 4A (RBP1-like),GO:0017053//transcriptional repressor complex;GO:0005634//nucleus,"GO:0048821//erythrocyte development;GO:0034773//histone H4-K20 trimethylation;GO:0006349//regulation of gene expression by genetic imprinting;GO:0080182//histone H3-K4 trimethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0036124//histone H3-K9 trimethylation;GO:0006366//transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K07874//Legionellosis
59269,0,0,0,0,13,22,0,0,77,113,24,0,HIVEP3;human immunodeficiency virus type I enhancer binding protein 3,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0035914//skeletal muscle cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
5927,14,49,7,24,117,48,40,58,73,0,26,3,KDM5A;lysine (K)-specific demethylase 5A,GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0055114//oxidation-reduction process;GO:0007275//multicellular organismal development;GO:0016568//chromatin modification","GO:0005515//protein binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity",-
59271,0,0,0,1,0,4,0,59,33,0,0,0,EVA1C;eva-1 homolog C (C. elegans),GO:0016021//integral component of membrane,-,GO:0030246//carbohydrate binding,-
59272,78,0,0,0,0,0,23,0,61,0,0,0,ACE2;angiotensin I converting enzyme 2,GO:0045121//membrane raft;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0042127//regulation of cell proliferation;GO:0002005//angiotensin catabolic process in blood;GO:0003051//angiotensin-mediated drinking behavior;GO:0046718//viral entry into host cell;GO:0001817//regulation of cytokine production;GO:0019229//regulation of vasoconstriction;GO:0044267//cellular protein metabolic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006508//proteolysis;GO:0003081//regulation of systemic arterial blood pressure by renin-angiotensin;GO:0042312//regulation of vasodilation;GO:0032800//receptor biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0046813//receptor-mediated virion attachment to host cell;GO:0002003//angiotensin maturation;GO:0009615//response to virus,GO:0017046//peptide hormone binding;GO:0001948//glycoprotein binding;GO:0004175//endopeptidase activity;GO:0001618//virus receptor activity;GO:0004180//carboxypeptidase activity;GO:0005515//protein binding;GO:0008241//peptidyl-dipeptidase activity;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding,K09708//Protein digestion and absorption;Renin-angiotensin system
59274,0,0,0,0,0,0,0,0,27,0,0,0,MESDC1;mesoderm development candidate 1,-,-,-,K06271//Focal adhesion;HTLV-I infection
59277,0,0,0,0,0,0,37,0,25,0,0,0,NTN4;netrin 4,GO:0005886//plasma membrane;GO:0005604//basement membrane,GO:0007411//axon guidance;GO:0016322//neuron remodeling;GO:0030198//extracellular matrix organization;GO:0060668//regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling,GO:0043237//laminin-1 binding,K06845//Axon guidance
5928,0,240,2,248,593,0,24,47,90,117,88,0,RBBP4;retinoblastoma binding protein 4,GO:0016589//NURF complex;GO:0016581//NuRD complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0033186//CAF-1 complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0016580//Sin3 complex;GO:0035098//ESC/E(Z) complex,"GO:0008285//negative regulation of cell proliferation;GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006200//ATP catabolic process;GO:0034080//CENP-A containing nucleosome assembly;GO:0031497//chromatin assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0043044//ATP-dependent chromatin remodeling;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006334//nucleosome assembly",GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0008094//DNA-dependent ATPase activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0042393//histone binding;GO:0042826//histone deacetylase binding;GO:0005515//protein binding,-
59283,0,0,0,0,0,0,19,0,29,0,0,0,"CACNG8;calcium channel, voltage-dependent, gamma subunit 8",GO:0005891//voltage-gated calcium channel complex;GO:0014069//postsynaptic density;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane,GO:0006816//calcium ion transport;GO:0007268//synaptic transmission;GO:0070588//calcium ion transmembrane transport;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,GO:0005245//voltage-gated calcium channel activity,K04873//Cardiac muscle contraction;Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Hypertrophic cardiomyopathy (HCM)
59284,0,0,0,0,0,0,0,0,14,0,0,0,"CACNG7;calcium channel, voltage-dependent, gamma subunit 7",GO:0005891//voltage-gated calcium channel complex;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0006816//calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,GO:0005245//voltage-gated calcium channel activity,K04872//Dilated cardiomyopathy;Cardiac muscle contraction;MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
59285,0,0,0,0,0,0,0,42,0,0,0,275,"CACNG6;calcium channel, voltage-dependent, gamma subunit 6",GO:0005891//voltage-gated calcium channel complex,GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity,K04871//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway;Dilated cardiomyopathy;Cardiac muscle contraction
59286,0,7,0,13,14,0,0,0,0,0,0,0,UBL5;ubiquitin-like 5,GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
5929,0,12,0,6,43,26,68,0,38,0,7,0,RBBP5;retinoblastoma binding protein 5,GO:0071339//MLL1 complex;GO:0048188//Set1C/COMPASS complex;GO:0005634//nucleus;GO:0035097//histone methyltransferase complex;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0006974//cellular response to DNA damage stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0043627//response to estrogen",GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0044212//transcription regulatory region DNA binding;GO:0035064//methylated histone binding;GO:0005515//protein binding,-
593,0,0,1,0,22,26,12,0,0,0,0,0,"BCKDHA;branched chain keto acid dehydrogenase E1, alpha polypeptide",GO:0005739//mitochondrion;GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex;GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0034641//cellular nitrogen compound metabolic process;GO:0051591//response to cAMP;GO:0009083//branched-chain amino acid catabolic process;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003863//3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity;GO:0016831//carboxy-lyase activity;GO:0003826//alpha-ketoacid dehydrogenase activity;GO:0032403//protein complex binding,"K00166//Valine, leucine and isoleucine degradation;Metabolic pathways;Biosynthesis of secondary metabolites"
5930,0,0,0,15,70,0,19,1,69,0,1,0,RBBP6;retinoblastoma binding protein 6,GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005694//chromosome;GO:0005730//nucleolus,GO:0048568//embryonic organ development;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0035264//multicellular organism growth;GO:0001701//in utero embryonic development;GO:0061053//somite development,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,-
59307,0,0,0,0,0,0,0,0,9,0,0,0,SIGIRR;single immunoglobulin and toll-interleukin 1 receptor (TIR) domain,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006953//acute-phase response;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045079//negative regulation of chemokine biosynthetic process;GO:0007165//signal transduction;GO:0001960//negative regulation of cytokine-mediated signaling pathway,GO:0005515//protein binding,-
5931,0,3,3,91,112,9,53,0,51,0,0,0,RBBP7;retinoblastoma binding protein 7,GO:0005654//nucleoplasm;GO:0035098//ESC/E(Z) complex;GO:0005634//nucleus;GO:0016581//NuRD complex,"GO:0034080//CENP-A containing nucleosome assembly;GO:0006334//nucleosome assembly;GO:0006260//DNA replication;GO:0030308//negative regulation of cell growth;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0070370//cellular heat acclimation;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003723//RNA binding,-
5932,0,0,0,0,37,0,0,0,22,44,0,0,RBBP8;retinoblastoma binding protein 8,GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0007126//meiotic nuclear division;GO:0000737//DNA catabolic process, endonucleolytic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000724//double-strand break repair via homologous recombination;GO:0000075//cell cycle checkpoint;GO:0000082//G1/S transition of mitotic cell cycle;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0031572//G2 DNA damage checkpoint;GO:0006281//DNA repair;GO:0007067//mitotic nuclear division;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001835//blastocyst hatching",GO:0003684//damaged DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0000014//single-stranded DNA endodeoxyribonuclease activity;GO:0005515//protein binding,-
5933,0,0,0,6,1,0,0,13,30,0,0,0,RBL1;retinoblastoma-like 1,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0016568//chromatin modification;GO:0043550//regulation of lipid kinase activity;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0008134//transcription factor binding,K04681//Cell cycle;TGF-beta signaling pathway
59335,0,0,0,0,0,0,0,91,26,0,9,0,PRDM12;PR domain containing 12,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0022008//neurogenesis;GO:0032259//methylation;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity,K12463//Neurotrophin signaling pathway
59336,33,0,0,0,0,20,0,0,28,0,0,81,PRDM13;PR domain containing 13,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032259//methylation;GO:0022008//neurogenesis;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0008168//methyltransferase activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
59338,4,25,0,25,58,32,0,0,41,0,0,0,"PLEKHA1;pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032587//ruffle membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0035264//multicellular organism growth;GO:0070301//cellular response to hydrogen peroxide;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:0031529//ruffle organization;GO:0033327//Leydig cell differentiation;GO:0050853//B cell receptor signaling pathway;GO:0045184//establishment of protein localization;GO:0008210//estrogen metabolic process;GO:0007283//spermatogenesis;GO:0008209//androgen metabolic process;GO:0001553//luteinization;GO:0051898//negative regulation of protein kinase B signaling;GO:0009791//post-embryonic development;GO:0048705//skeletal system morphogenesis,"GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",K11447//Transcriptional misregulation in cancer;K12229//B cell receptor signaling pathway;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
59339,0,0,0,0,12,0,28,0,32,0,1,0,"PLEKHA2;pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0001954//positive regulation of cell-matrix adhesion,GO:0043236//laminin binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0001968//fibronectin binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
5934,0,134,2,56,162,0,15,0,13,0,51,0,RBL2;retinoblastoma-like 2,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0043550//regulation of lipid kinase activity;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification",GO:0003677//DNA binding;GO:0005515//protein binding,K04681//Cell cycle;TGF-beta signaling pathway
59340,0,0,0,0,0,34,0,0,10,0,0,0,HRH4;histamine receptor H4,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0043408//regulation of MAPK cascade;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006954//inflammatory response,GO:0004969//histamine receptor activity,K04152//Neuroactive ligand-receptor interaction
59341,0,0,0,0,0,6,14,0,22,0,9,0,"TRPV4;transient receptor potential cation channel, subfamily V, member 4",GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0031410//cytoplasmic vesicle;GO:0030426//growth cone;GO:0005929//cilium;GO:0032587//ruffle membrane;GO:0005925//focal adhesion;GO:0005912//adherens junction;GO:0030864//cortical actin cytoskeleton,GO:0031117//positive regulation of microtubule depolymerization;GO:0046785//microtubule polymerization;GO:0030103//vasopressin secretion;GO:0007015//actin filament organization;GO:0070588//calcium ion transmembrane transport;GO:0006884//cell volume homeostasis;GO:0071476//cellular hypotonic response;GO:0009612//response to mechanical stimulus;GO:0034220//ion transmembrane transport;GO:0010977//negative regulation of neuron projection development;GO:0007043//cell-cell junction assembly;GO:0008219//cell death;GO:0043622//cortical microtubule organization;GO:0047484//regulation of response to osmotic stress;GO:0070509//calcium ion import;GO:0034605//cellular response to heat;GO:0007231//osmosensory signaling pathway;GO:0006874//cellular calcium ion homeostasis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0055085//transmembrane transport;GO:0006816//calcium ion transport;GO:0071470//cellular response to osmotic stress;GO:0031532//actin cytoskeleton reorganization;GO:0042538//hyperosmotic salinity response,GO:0005034//osmosensor activity;GO:0005261//cation channel activity;GO:0042169//SH2 domain binding;GO:0043014//alpha-tubulin binding;GO:0005262//calcium channel activity;GO:0048487//beta-tubulin binding;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0008017//microtubule binding;GO:0019901//protein kinase binding;GO:0051015//actin filament binding;GO:0005080//protein kinase C binding,-
59342,0,0,0,0,23,8,30,0,23,0,21,0,SCPEP1;serine carboxypeptidase 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0045776//negative regulation of blood pressure;GO:0006508//proteolysis;GO:0042573//retinoic acid metabolic process;GO:0045909//positive regulation of vasodilation,GO:0004185//serine-type carboxypeptidase activity,-
59343,0,0,0,30,100,48,0,1,21,76,0,640,SENP2;SUMO1/sentrin/SMT3 specific peptidase 2,GO:0016605//PML body;GO:0005643//nuclear pore;GO:0031965//nuclear membrane;GO:0031410//cytoplasmic vesicle;GO:0005654//nucleoplasm,"GO:0032091//negative regulation of protein binding;GO:0015031//protein transport;GO:0016926//protein desumoylation;GO:0007507//heart development;GO:0060707//trophoblast giant cell differentiation;GO:0051028//mRNA transport;GO:0030111//regulation of Wnt signaling pathway;GO:0044267//cellular protein metabolic process;GO:0060712//spongiotrophoblast layer development;GO:0001934//positive regulation of protein phosphorylation;GO:0006508//proteolysis;GO:0009950//dorsal/ventral axis specification;GO:0032875//regulation of DNA endoreduplication;GO:0016925//protein sumoylation;GO:0060711//labyrinthine layer development;GO:0035562//negative regulation of chromatin binding;GO:0016055//Wnt signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043687//post-translational protein modification;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0016929//SUMO-specific protease activity;GO:0005515//protein binding;GO:0019904//protein domain specific binding,K03345//Wnt signaling pathway;RNA transport
59344,0,0,0,0,0,0,58,1,54,0,0,0,ALOXE3;arachidonate lipoxygenase 3,GO:0005737//cytoplasm,GO:0019233//sensory perception of pain;GO:0045444//fat cell differentiation;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0051122//hepoxilin biosynthetic process;GO:0019372//lipoxygenase pathway;GO:0043651//linoleic acid metabolic process;GO:0006665//sphingolipid metabolic process;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0046513//ceramide biosynthetic process;GO:0061436//establishment of skin barrier,"GO:0005506//iron ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0005515//protein binding;GO:0051120//hepoxilin A3 synthase activity",K08021//Arachidonic acid metabolism;Metabolic pathways;Serotonergic synapse
59345,0,2,1,0,83,0,22,43,16,0,17,0,"GNB4;guanine nucleotide binding protein (G protein), beta polypeptide 4",GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0021762//substantia nigra development;GO:0007165//signal transduction;GO:0008219//cell death;GO:0071377//cellular response to glucagon stimulus;GO:0006112//energy reserve metabolic process,GO:0032403//protein complex binding;GO:0004871//signal transducer activity,K04538//Glutamatergic synapse;Morphine addiction;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Cholinergic synapse;Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling
59348,43,49,57,80,143,0,0,0,0,0,35,0,ZNF350;zinc finger protein 350,GO:0005730//nucleolus;GO:0017053//transcriptional repressor complex;GO:0005634//nucleus;GO:0016363//nuclear matrix,"GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
59349,0,88,1,58,87,0,14,0,28,0,2,0,KLHL12;kelch-like family member 12,GO:0000139//Golgi membrane;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0030134//ER to Golgi transport vesicle,GO:0048208//COPII vesicle coating;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0016055//Wnt signaling pathway;GO:0006513//protein monoubiquitination,GO:0005515//protein binding,-
5935,0,1,1,3,27,22,41,1,29,0,0,0,"RBM3;RNA binding motif (RNP1, RRM) protein 3",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030425//dendrite;GO:0015934//large ribosomal subunit,GO:0006417//regulation of translation;GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0006396//RNA processing;GO:0009409//response to cold;GO:0006412//translation;GO:0045727//positive regulation of translation,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0043023//ribosomal large subunit binding;GO:0005515//protein binding;GO:0003723//RNA binding,-
59350,0,0,0,0,0,15,0,0,23,0,0,0,RXFP1;relaxin/insulin-like family peptide receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007567//parturition;GO:0060658//nipple morphogenesis;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0030154//cell differentiation;GO:0060427//lung connective tissue development,GO:0004930//G-protein coupled receptor activity;GO:0042562//hormone binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K04306//Neuroactive ligand-receptor interaction
59351,0,0,0,1,0,8,0,0,9,0,0,0,PBOV1;prostate and breast cancer overexpressed 1,GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
59352,167,0,19,0,0,23,0,0,26,39,0,0,LGR6;leucine-rich repeat containing G protein-coupled receptor 6,GO:0005887//integral component of plasma membrane;GO:0031982//vesicle;GO:0032588//trans-Golgi network membrane,GO:0030335//positive regulation of cell migration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016055//Wnt signaling pathway;GO:0030177//positive regulation of Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity,-
59353,0,0,0,0,0,0,6,0,13,0,0,0,TMEM35;transmembrane protein 35,GO:0016021//integral component of membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005778//peroxisomal membrane,-,-,-
5936,0,63,0,15,30,9,1,0,5,0,0,0,RBM4;RNA binding motif protein 4,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0046685//response to arsenic-containing substance;GO:0051403//stress-activated MAPK cascade;GO:0006397//mRNA processing;GO:0097167//circadian regulation of translation;GO:0008380//RNA splicing;GO:0046822//regulation of nucleocytoplasmic transport;GO:0002192//IRES-dependent translational initiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0043153//entrainment of circadian clock by photoperiod;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0032055//negative regulation of translation in response to stress;GO:0017148//negative regulation of translation;GO:0006396//RNA processing;GO:0045947//negative regulation of translational initiation;GO:0030154//cell differentiation",GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0097158//pre-mRNA intronic pyrimidine-rich binding;GO:0035198//miRNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0008270//zinc ion binding;GO:0003729//mRNA binding;GO:0097157//pre-mRNA intronic binding;GO:0003723//RNA binding,-
5937,51,0,0,0,19,40,25,0,56,0,0,0,"RBMS1;RNA binding motif, single stranded interacting protein 1",GO:0005634//nucleus,GO:0006396//RNA processing;GO:0006260//DNA replication,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding;GO:0003690//double-stranded DNA binding,-
5939,2,0,0,59,45,0,20,0,53,5,0,0,"RBMS2;RNA binding motif, single stranded interacting protein 2",GO:0005634//nucleus,GO:0006396//RNA processing,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,K11447//Transcriptional misregulation in cancer
594,0,0,0,11,90,14,0,0,22,0,0,0,"BCKDHB;branched chain keto acid dehydrogenase E1, beta polypeptide",GO:0005947//mitochondrial alpha-ketoglutarate dehydrogenase complex;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0051384//response to glucocorticoid;GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0009083//branched-chain amino acid catabolic process;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0051591//response to cAMP,GO:0016831//carboxy-lyase activity;GO:0003863//3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity;GO:0005515//protein binding;GO:0032403//protein complex binding;GO:0003826//alpha-ketoacid dehydrogenase activity,"K00167//Biosynthesis of secondary metabolites;Valine, leucine and isoleucine degradation;Metabolic pathways"
5947,0,0,0,0,0,5,0,0,40,0,6,0,"RBP1;retinol binding protein 1, cellular",GO:0005829//cytosol,"GO:0006776//vitamin A metabolic process;GO:0006810//transport;GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light",GO:0005501//retinoid binding;GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0005215//transporter activity,K06210//Metabolic pathways;Nicotinate and nicotinamide metabolism
5948,0,0,0,0,0,0,0,22,14,0,0,0,"RBP2;retinol binding protein 2, cellular",GO:0005829//cytosol,"GO:0008544//epidermis development;GO:0007603//phototransduction, visible light;GO:0001523//retinoid metabolic process;GO:0006810//transport;GO:0006776//vitamin A metabolic process",GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0005501//retinoid binding;GO:0005215//transporter activity,K14622//Vitamin digestion and absorption
594839,0,0,0,0,0,0,0,0,16,0,0,0,"SNORA33;small nucleolar RNA, H/ACA box 33",-,-,-,-
594855,0,0,0,0,0,0,0,0,66,0,0,0,CPLX3;complexin 3,GO:0005829//cytosol;GO:0045202//synapse;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0016079//synaptic vesicle exocytosis;GO:0030073//insulin secretion;GO:0046928//regulation of neurotransmitter secretion,GO:0005326//neurotransmitter transporter activity;GO:0019905//syntaxin binding,K15295//Synaptic vesicle cycle
5949,0,0,0,0,0,11,0,119,26,0,0,0,"RBP3;retinol binding protein 3, interstitial",GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031982//vesicle;GO:0033165//interphotoreceptor matrix,"GO:0007603//phototransduction, visible light;GO:0001523//retinoid metabolic process;GO:0006810//transport;GO:0006629//lipid metabolic process;GO:0006508//proteolysis;GO:0007601//visual perception",GO:0005501//retinoid binding;GO:0019841//retinol binding;GO:0016918//retinal binding;GO:0008236//serine-type peptidase activity,-
595,0,39,42,64,386,0,1,1,56,0,40,0,CCND1;cyclin D1,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005622//intracellular;GO:0005923//tight junction;GO:0005634//nucleus;GO:0016020//membrane;GO:0017053//transcriptional repressor complex;GO:0005654//nucleoplasm;GO:0000307//cyclin-dependent protein kinase holoenzyme complex,"GO:0051412//response to corticosterone;GO:0001934//positive regulation of protein phosphorylation;GO:0051592//response to calcium ion;GO:0007595//lactation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0033197//response to vitamin E;GO:0033598//mammary gland epithelial cell proliferation;GO:0060749//mammary gland alveolus development;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0006351//transcription, DNA-templated;GO:0001889//liver development;GO:0010165//response to X-ray;GO:0000278//mitotic cell cycle;GO:0043627//response to estrogen;GO:0006468//protein phosphorylation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0000320//re-entry into mitotic cell cycle;GO:0006974//cellular response to DNA damage stimulus;GO:0045444//fat cell differentiation;GO:0032026//response to magnesium ion;GO:0030178//negative regulation of Wnt signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0010243//response to organonitrogen compound;GO:0007219//Notch signaling pathway;GO:0030857//negative regulation of epithelial cell differentiation;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0070141//response to UV-A;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0060070//canonical Wnt signaling pathway;GO:0071157//negative regulation of cell cycle arrest;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045471//response to ethanol;GO:0051301//cell division;GO:0042493//response to drug;GO:0031100//organ regeneration;GO:0033327//Leydig cell differentiation;GO:0010039//response to iron ion",GO:0019899//enzyme binding;GO:0003714//transcription corepressor activity;GO:0032403//protein complex binding;GO:0070064//proline-rich region binding;GO:0042826//histone deacetylase binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005515//protein binding;GO:0008134//transcription factor binding,K04503//HTLV-I infection;Acute myeloid leukemia;Jak-STAT signaling pathway;Glioma;p53 signaling pathway;Measles;Focal adhesion;Thyroid cancer;Non-small cell lung cancer;Endometrial cancer;Melanoma;Prostate cancer;Small cell lung cancer;Pathways in cancer;Pancreatic cancer;Bladder cancer;Cell cycle;Colorectal cancer;Viral myocarditis;Chronic myeloid leukemia;Wnt signaling pathway
595135,0,11,0,2,34,0,1,1,0,0,13,0,PGM5P2;phosphoglucomutase 5 pseudogene 2,-,-,-,-
5954,5,0,24,0,15,0,0,1,0,1,0,0,"RCN1;reticulocalbin 1, EF-hand calcium binding domain",GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum,GO:0043010//camera-type eye development;GO:0001701//in utero embryonic development,GO:0005509//calcium ion binding;GO:0005515//protein binding,K05865//Cardiac muscle contraction;Calcium signaling pathway;Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM);K02183//Melanogenesis;Gastric acid secretion;Glioma;Alzheimer's disease;Neurotrophin signaling pathway;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Plant-pathogen interaction;Phototransduction - fly;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Long-term potentiation;Pertussis;Tuberculosis;Alcoholism;Phototransduction;Insulin signaling pathway;Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system
5955,0,0,0,0,4,0,43,0,48,0,0,0,"RCN2;reticulocalbin 2, EF-hand calcium binding domain",GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus,-,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
5956,0,0,0,0,0,0,0,3,0,0,0,0,"OPN1LW;opsin 1 (cone pigments), long-wave-sensitive",GO:0005887//integral component of plasma membrane;GO:0042622//photoreceptor outer segment membrane,"GO:0018298//protein-chromophore linkage;GO:0007603//phototransduction, visible light;GO:0001523//retinoid metabolic process;GO:0032467//positive regulation of cytokinesis;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0007601//visual perception",GO:0004930//G-protein coupled receptor activity;GO:0009881//photoreceptor activity,-
5959,0,0,0,0,0,0,0,45,0,22,0,379,RDH5;retinol dehydrogenase 5 (11-cis/9-cis),GO:0005788//endoplasmic reticulum lumen;GO:0044297//cell body;GO:0005789//endoplasmic reticulum membrane,"GO:0007601//visual perception;GO:0001523//retinoid metabolic process;GO:0055114//oxidation-reduction process;GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light",GO:0004745//retinol dehydrogenase activity,K00061//Retinol metabolism
596,0,20,0,19,53,17,27,33,99,0,0,0,BCL2;B-cell CLL/lymphoma 2,GO:0046930//pore complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0043209//myelin sheath,"GO:0030318//melanocyte differentiation;GO:0009791//post-embryonic development;GO:0040018//positive regulation of multicellular organism growth;GO:0043496//regulation of protein homodimerization activity;GO:0008584//male gonad development;GO:0007015//actin filament organization;GO:0043375//CD8-positive, alpha-beta T cell lineage commitment;GO:0006470//protein dephosphorylation;GO:0033689//negative regulation of osteoblast proliferation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0048599//oocyte development;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0072593//reactive oxygen species metabolic process;GO:0002326//B cell lineage commitment;GO:0043029//T cell homeostasis;GO:0014911//positive regulation of smooth muscle cell migration;GO:0016049//cell growth;GO:0007565//female pregnancy;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0006582//melanin metabolic process;GO:0010559//regulation of glycoprotein biosynthetic process;GO:0016337//single organismal cell-cell adhesion;GO:0071310//cellular response to organic substance;GO:0035265//organ growth;GO:0030336//negative regulation of cell migration;GO:0030307//positive regulation of cell growth;GO:0001662//behavioral fear response;GO:0045636//positive regulation of melanocyte differentiation;GO:0003014//renal system process;GO:0006974//cellular response to DNA damage stimulus;GO:0001836//release of cytochrome c from mitochondria;GO:0048546//digestive tract morphogenesis;GO:0001782//B cell homeostasis;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0014042//positive regulation of neuron maturation;GO:0007569//cell aging;GO:0006915//apoptotic process;GO:0022612//gland morphogenesis;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0009314//response to radiation;GO:0001541//ovarian follicle development;GO:0030890//positive regulation of B cell proliferation;GO:0050853//B cell receptor signaling pathway;GO:0007409//axonogenesis;GO:0071456//cellular response to hypoxia;GO:0031069//hair follicle morphogenesis;GO:0030279//negative regulation of ossification;GO:0032835//glomerulus development;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0042100//B cell proliferation;GO:0042493//response to drug;GO:0048873//homeostasis of number of cells within a tissue;GO:0001952//regulation of cell-matrix adhesion;GO:0051902//negative regulation of mitochondrial depolarization;GO:0033033//negative regulation of myeloid cell apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0046902//regulation of mitochondrial membrane permeability;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0042149//cellular response to glucose starvation;GO:0035094//response to nicotine;GO:0048589//developmental growth;GO:0022898//regulation of transmembrane transporter activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0033077//T cell differentiation in thymus;GO:0051924//regulation of calcium ion transport;GO:0018107//peptidyl-threonine phosphorylation;GO:0051881//regulation of mitochondrial membrane potential;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0009636//response to toxic substance;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0048536//spleen development;GO:0045930//negative regulation of mitotic cell cycle;GO:0045069//regulation of viral genome replication;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0043066//negative regulation of apoptotic process;GO:0042542//response to hydrogen peroxide;GO:0030308//negative regulation of cell growth;GO:0010224//response to UV-B;GO:0000209//protein polyubiquitination;GO:0001101//response to acid chemical;GO:0002931//response to ischemia;GO:2000811//negative regulation of anoikis;GO:0014031//mesenchymal cell development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0018105//peptidyl-serine phosphorylation;GO:0048041//focal adhesion assembly;GO:0043497//regulation of protein heterodimerization activity;GO:0046671//negative regulation of retinal cell programmed cell death;GO:0051607//defense response to virus;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0010507//negative regulation of autophagy;GO:0043085//positive regulation of catalytic activity;GO:0006959//humoral immune response;GO:0048753//pigment granule organization;GO:0034097//response to cytokine;GO:0032848//negative regulation of cellular pH reduction;GO:0001656//metanephros development;GO:0010039//response to iron ion;GO:0051384//response to glucocorticoid;GO:0048538//thymus development;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0001503//ossification;GO:0031647//regulation of protein stability;GO:0031103//axon regeneration;GO:0097193//intrinsic apoptotic signaling pathway;GO:0021747//cochlear nucleus development;GO:0002320//lymphoid progenitor cell differentiation;GO:0055085//transmembrane transport;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043583//ear development;GO:0010332//response to gamma radiation;GO:0051402//neuron apoptotic process;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0006808//regulation of nitrogen utilization;GO:0010523//negative regulation of calcium ion transport into cytosol",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0016248//channel inhibitor activity;GO:0008134//transcription factor binding;GO:0051721//protein phosphatase 2A binding;GO:0051434//BH3 domain binding;GO:0002020//protease binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0015267//channel activity,K02161//Apoptosis;Toxoplasmosis;Protein processing in endoplasmic reticulum;Neurotrophin signaling pathway;Amyotrophic lateral sclerosis (ALS);Colorectal cancer;Epstein-Barr virus infection;Focal adhesion;Pathways in cancer;Cholinergic synapse;NF-kappa B signaling pathway;Prostate cancer;Tuberculosis;Small cell lung cancer
5961,46,0,0,0,0,24,64,0,1,0,0,0,"PRPH2;peripherin 2 (retinal degeneration, slow)",GO:0016021//integral component of membrane,GO:0007601//visual perception;GO:0007155//cell adhesion;GO:0060041//retina development in camera-type eye,-,K07607//Amyotrophic lateral sclerosis (ALS)
5962,0,0,0,31,130,29,0,43,85,0,7,0,RDX;radixin,GO:0032420//stereocilium;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0045177//apical part of cell;GO:0030027//lamellipodium;GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0051286//cell tip;GO:0001726//ruffle;GO:0032154//cleavage furrow;GO:0030315//T-tubule;GO:0030175//filopodium;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0045176//apical protein localization;GO:0010628//positive regulation of gene expression;GO:0051693//actin filament capping;GO:0061028//establishment of endothelial barrier;GO:0030033//microvillus assembly,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003779//actin binding,K05762//Regulation of actin cytoskeleton
5965,0,2,132,168,243,41,13,0,6,0,112,0,RECQL;RecQ helicase-like,GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,GO:0000733//DNA strand renaturation;GO:0006200//ATP catabolic process;GO:0032508//DNA duplex unwinding;GO:0006310//DNA recombination;GO:0006260//DNA replication;GO:0006281//DNA repair,GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0003678//DNA helicase activity;GO:0036310//annealing helicase activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
5966,0,16,0,0,46,50,0,0,17,0,6,0,REL;v-rel avian reticuloendotheliosis viral oncogene homolog,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0001816//cytokine production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901215//negative regulation of neuron death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007249//I-kappaB kinase/NF-kappaB signaling",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K09254//Transcriptional misregulation in cancer
5968,0,0,0,0,0,0,19,0,0,0,0,0,REG1B;regenerating islet-derived 1 beta,GO:0070062//extracellular vesicular exosome,GO:0008283//cell proliferation,GO:0030246//carbohydrate binding,K06560//Phagosome;Tuberculosis
5970,0,0,0,0,20,41,26,1,28,0,5,25,RELA;v-rel avian reticuloendotheliosis viral oncogene homolog A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0034146//toll-like receptor 5 signaling pathway;GO:0009887//organ morphogenesis;GO:0033590//response to cobalamin;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006117//acetaldehyde metabolic process;GO:0016032//viral process;GO:0007568//aging;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070301//cellular response to hydrogen peroxide;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0032332//positive regulation of chondrocyte differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042493//response to drug;GO:0042177//negative regulation of protein catabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0009612//response to mechanical stimulus;GO:0071354//cellular response to interleukin-6;GO:0006366//transcription from RNA polymerase II promoter;GO:0043200//response to amino acid;GO:0051591//response to cAMP;GO:0071375//cellular response to peptide hormone stimulus;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070555//response to interleukin-1;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010224//response to UV-B;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0001889//liver development;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0001942//hair follicle development;GO:0050852//T cell receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0071347//cellular response to interleukin-1;GO:0032495//response to muramyl dipeptide;GO:0071356//cellular response to tumor necrosis factor;GO:0071222//cellular response to lipopolysaccharide;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0050727//regulation of inflammatory response;GO:0032868//response to insulin;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0010033//response to organic substance;GO:0045893//positive regulation of transcription, DNA-templated;GO:0031293//membrane protein intracellular domain proteolysis;GO:0071316//cellular response to nicotine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006968//cellular defense response;GO:0032570//response to progesterone;GO:0043278//response to morphine;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:2000630//positive regulation of miRNA metabolic process;GO:0014040//positive regulation of Schwann cell differentiation;GO:0051607//defense response to virus",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0071532//ankyrin repeat binding;GO:0033613//activating transcription factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0032403//protein complex binding;GO:0042301//phosphate ion binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0070491//repressing transcription factor binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0051059//NF-kappaB binding;GO:0047485//protein N-terminus binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K04735//Pertussis;Influenza A;Toll-like receptor signaling pathway;Chemokine signaling pathway;Pathways in cancer;Cocaine addiction;Pancreatic cancer;NF-kappa B signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;RIG-I-like receptor signaling pathway;Apoptosis;MAPK signaling pathway;Herpes simplex infection;Legionellosis;NOD-like receptor signaling pathway;Shigellosis;HTLV-I infection;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation;Prostate cancer;Tuberculosis;Small cell lung cancer;Salmonella infection;Amoebiasis;T cell receptor signaling pathway;Chronic myeloid leukemia;Transcriptional misregulation in cancer;B cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Acute myeloid leukemia;Measles;Adipocytokine signaling pathway;Hepatitis C;Neurotrophin signaling pathway;Cytosolic DNA-sensing pathway
5971,0,0,0,0,0,0,0,0,20,0,1,0,RELB;v-rel avian reticuloendotheliosis viral oncogene homolog B,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0043011//myeloid dendritic cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0038061//NIK/NF-kappaB signaling;GO:0045063//T-helper 1 cell differentiation;GO:0010628//positive regulation of gene expression;GO:0019882//antigen processing and presentation;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001047//core promoter binding;GO:0003714//transcription corepressor activity,K09253//Osteoclast differentiation;MAPK signaling pathway;NF-kappa B signaling pathway;HTLV-I infection;Epstein-Barr virus infection
5972,0,0,0,0,0,0,0,1,8,0,0,0,REN;renin,GO:0005615//extracellular space;GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0035690//cellular response to drug;GO:0032496//response to lipopolysaccharide;GO:0001823//mesonephros development;GO:0002003//angiotensin maturation;GO:0043408//regulation of MAPK cascade;GO:0050435//beta-amyloid metabolic process;GO:0048469//cell maturation;GO:0001822//kidney development;GO:0070305//response to cGMP;GO:0002018//renin-angiotensin regulation of aldosterone production;GO:0008217//regulation of blood pressure;GO:0044267//cellular protein metabolic process;GO:0008584//male gonad development;GO:0006508//proteolysis;GO:0051591//response to cAMP;GO:0009755//hormone-mediated signaling pathway;GO:0042756//drinking behavior,GO:0004190//aspartic-type endopeptidase activity;GO:0008233//peptidase activity;GO:0005102//receptor binding;GO:0005159//insulin-like growth factor receptor binding,K01380//Renin-angiotensin system
5973,0,0,0,0,0,0,7,0,52,0,0,0,RENBP;renin binding protein,GO:0070062//extracellular vesicular exosome,GO:0010951//negative regulation of endopeptidase activity;GO:0008217//regulation of blood pressure;GO:0019262//N-acetylneuraminate catabolic process;GO:0006051//N-acetylmannosamine metabolic process;GO:0006044//N-acetylglucosamine metabolic process,GO:0042803//protein homodimerization activity;GO:0050121//N-acylglucosamine 2-epimerase activity;GO:0004866//endopeptidase inhibitor activity;GO:0005524//ATP binding,K01787//Amino sugar and nucleotide sugar metabolism;K14966//Herpes simplex infection
5976,47,33,1,2,66,0,0,2,19,0,7,0,UPF1;UPF1 regulator of nonsense transcripts homolog (yeast),GO:0000785//chromatin;GO:0005634//nucleus;GO:0044530//supraspliceosomal complex;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0005737//cytoplasm;GO:0000932//cytoplasmic mRNA processing body,"GO:0010467//gene expression;GO:0071044//histone mRNA catabolic process;GO:0006260//DNA replication;GO:0009048//dosage compensation by inactivation of X chromosome;GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006449//regulation of translational termination;GO:0006200//ATP catabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0006281//DNA repair;GO:0016071//mRNA metabolic process;GO:0006406//mRNA export from nucleus",GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0003723//RNA binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0008270//zinc ion binding,K14326//mRNA surveillance pathway;RNA transport
5977,0,2,0,5,1,12,22,1,23,0,1,0,"DPF2;D4, zinc and double PHD fingers family 2",GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0097190//apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
5978,0,59,1,50,145,19,22,1,35,0,0,0,REST;RE1-silencing transcription factor,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex;GO:0005829//cytosol,"GO:0043065//positive regulation of apoptotic process;GO:0046676//negative regulation of insulin secretion;GO:0071257//cellular response to electrical stimulus;GO:0070933//histone H4 deacetylation;GO:0050768//negative regulation of neurogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0071385//cellular response to glucocorticoid stimulus;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0071805//potassium ion transmembrane transport;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000798//negative regulation of amniotic stem cell differentiation;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0060379//cardiac muscle cell myoblast differentiation;GO:0035690//cellular response to drug;GO:0045665//negative regulation of neuron differentiation;GO:0002244//hematopoietic progenitor cell differentiation;GO:2000706//negative regulation of dense core granule biogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:2000065//negative regulation of cortisol biosynthetic process;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0043922//negative regulation by host of viral transcription",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008134//transcription factor binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003682//chromatin binding;GO:0001047//core promoter binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0015271//outward rectifier potassium channel activity,K09222//Huntington's disease
5979,0,0,0,0,10,31,0,3,78,288,2,360,RET;ret proto-oncogene,GO:0010008//endosome membrane;GO:0045121//membrane raft;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane,"GO:0007158//neuron cell-cell adhesion;GO:0001838//embryonic epithelial tube formation;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0035799//ureter maturation;GO:0097021//lymphocyte migration into lymphoid organs;GO:0050770//regulation of axonogenesis;GO:0060041//retina development in camera-type eye;GO:0061146//Peyer's patch morphogenesis;GO:0030155//regulation of cell adhesion;GO:0071300//cellular response to retinoic acid;GO:0060384//innervation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0001755//neural crest cell migration;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042493//response to drug;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045793//positive regulation of cell size;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0048484//enteric nervous system development;GO:0000165//MAPK cascade;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0007497//posterior midgut development;GO:0030335//positive regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0072300//positive regulation of metanephric glomerulus development;GO:0010976//positive regulation of neuron projection development;GO:0001657//ureteric bud development;GO:0042551//neuron maturation;GO:0007165//signal transduction;GO:0033619//membrane protein proteolysis;GO:0014042//positive regulation of neuron maturation;GO:0006468//protein phosphorylation;GO:0048265//response to pain",GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004872//receptor activity;GO:0005524//ATP binding,K05126//Thyroid cancer;Pathways in cancer;Endocytosis
598,0,12,0,11,69,0,3,61,19,0,1,0,BCL2L1;BCL2-like 1,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0097136//Bcl-2 family protein complex;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0031965//nuclear membrane;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix,"GO:0071312//cellular response to alkaloid;GO:0090201//negative regulation of release of cytochrome c from mitochondria;GO:0043524//negative regulation of neuron apoptotic process;GO:0008637//apoptotic mitochondrial changes;GO:0071480//cellular response to gamma radiation;GO:0040007//growth;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:1900118//negative regulation of execution phase of apoptosis;GO:0006897//endocytosis;GO:0051881//regulation of mitochondrial membrane potential;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0060154//cellular process regulating host cell cycle in response to virus;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0008284//positive regulation of cell proliferation;GO:0007093//mitotic cell cycle checkpoint;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0019050//suppression by virus of host apoptotic process;GO:0045087//innate immune response;GO:0043066//negative regulation of apoptotic process;GO:0097284//hepatocyte apoptotic process;GO:2000811//negative regulation of anoikis;GO:0008283//cell proliferation;GO:0071839//apoptotic process in bone marrow;GO:0001836//release of cytochrome c from mitochondria;GO:0000910//cytokinesis;GO:0046898//response to cycloheximide;GO:0010507//negative regulation of autophagy;GO:0009566//fertilization;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0034097//response to cytokine;GO:0006915//apoptotic process;GO:0001541//ovarian follicle development;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0071230//cellular response to amino acid stimulus;GO:0001701//in utero embryonic development;GO:0007281//germ cell development;GO:0070584//mitochondrion morphogenesis;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0046902//regulation of mitochondrial membrane permeability;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0051402//neuron apoptotic process",GO:0051434//BH3 domain binding;GO:0019901//protein kinase binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K04570//Transcriptional misregulation in cancer;Small cell lung cancer;Pathways in cancer;Pancreatic cancer;HTLV-I infection;NF-kappa B signaling pathway;Jak-STAT signaling pathway;Apoptosis;Toxoplasmosis;Chronic myeloid leukemia;Amyotrophic lateral sclerosis (ALS)
5980,0,22,0,35,57,35,97,67,55,197,39,0,"REV3L;REV3-like, polymerase (DNA directed), zeta, catalytic subunit",GO:0005634//nucleus;GO:0016035//zeta DNA polymerase complex;GO:0005694//chromosome,"GO:0019985//translesion synthesis;GO:0006261//DNA-dependent DNA replication;GO:0006297//nucleotide-excision repair, DNA gap filling","GO:0003887//DNA-directed DNA polymerase activity;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0008408//3'-5' exonuclease activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0051539//4 iron, 4 sulfur cluster binding",K02350//Metabolic pathways;Fanconi anemia pathway
5981,0,12,0,8,42,48,0,44,24,0,10,0,"RFC1;replication factor C (activator 1) 1, 145kDa",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005663//DNA replication factor C complex,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0000278//mitotic cell cycle;GO:0043085//positive regulation of catalytic activity;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006261//DNA-dependent DNA replication;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006351//transcription, DNA-templated;GO:0000723//telomere maintenance;GO:0007004//telomere maintenance via telomerase;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005524//ATP binding;GO:0008047//enzyme activator activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003689//DNA clamp loader activity;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding,K10754//Mismatch repair;DNA replication;Nucleotide excision repair
5982,0,0,0,0,36,0,4,0,25,0,0,34,"RFC2;replication factor C (activator 1) 2, 40kDa",GO:0005663//DNA replication factor C complex;GO:0005654//nucleoplasm,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0005524//ATP binding,K10755//Nucleotide excision repair;DNA replication;Mismatch repair
5983,0,18,0,20,62,19,0,0,52,0,0,0,"RFC3;replication factor C (activator 1) 3, 38kDa",GO:0005663//DNA replication factor C complex;GO:0005654//nucleoplasm,"GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000731//DNA synthesis involved in DNA repair;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0006200//ATP catabolic process;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair",GO:0003689//DNA clamp loader activity;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0005515//protein binding,K10756//Nucleotide excision repair;DNA replication;Mismatch repair
5984,0,20,0,8,19,11,0,40,25,0,1,0,"RFC4;replication factor C (activator 1) 4, 37kDa",GO:0005654//nucleoplasm;GO:0005663//DNA replication factor C complex,"GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair",GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0005515//protein binding,K10755//DNA replication;Nucleotide excision repair;Mismatch repair
5985,0,58,63,63,40,0,31,0,20,0,104,0,"RFC5;replication factor C (activator 1) 5, 36.5kDa",GO:0005663//DNA replication factor C complex;GO:0005654//nucleoplasm,"GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000722//telomere maintenance via recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000723//telomere maintenance;GO:0006297//nucleotide-excision repair, DNA gap filling",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0019899//enzyme binding;GO:0005524//ATP binding,K10756//DNA replication;Nucleotide excision repair;Mismatch repair
5986,27,0,0,0,0,18,0,37,0,0,0,0,RFNG;RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0030173//integral component of Golgi membrane,GO:0030154//cell differentiation;GO:0032092//positive regulation of protein binding;GO:0009887//organ morphogenesis;GO:0007389//pattern specification process;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0045747//positive regulation of Notch signaling pathway,GO:0033829//O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity;GO:0046872//metal ion binding,K05948//Notch signaling pathway;Other types of O-glycan biosynthesis
5987,0,0,0,0,0,0,0,0,10,0,0,0,TRIM27;tripartite motif containing 27,GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0016605//PML body;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0030904//retromer complex;GO:0005768//endosome;GO:0005769//early endosome;GO:0016020//membrane,"GO:0002820//negative regulation of adaptive immune response;GO:0042147//retrograde transport, endosome to Golgi;GO:0006469//negative regulation of protein kinase activity;GO:0045087//innate immune response;GO:1902187//negative regulation of viral release from host cell;GO:0032897//negative regulation of viral transcription;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0090281//negative regulation of calcium ion import;GO:0034314//Arp2/3 complex-mediated actin nucleation;GO:0045814//negative regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation;GO:0072643//interferon-gamma secretion;GO:0070206//protein trimerization;GO:0070534//protein K63-linked ubiquitination;GO:0007283//spermatogenesis;GO:1900041//negative regulation of interleukin-2 secretion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032720//negative regulation of tumor necrosis factor production",GO:0016874//ligase activity;GO:0003677//DNA binding;GO:0003676//nucleic acid binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0046872//metal ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
5988,0,58,105,225,286,0,0,1,42,0,257,0,RFPL1;ret finger protein-like 1,-,-,GO:0008270//zinc ion binding,K12803//NOD-like receptor signaling pathway
5989,90,0,0,9,1,0,0,0,72,176,1,0,"RFX1;regulatory factor X, 1 (influences HLA class II expression)",GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006955//immune response,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
5990,0,0,0,8,2,0,47,42,88,0,22,0,"RFX2;regulatory factor X, 2 (influences HLA class II expression)",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
5991,5,0,0,26,12,9,0,0,57,0,0,0,"RFX3;regulatory factor X, 3 (influences HLA class II expression)",GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex,"GO:0042384//cilium assembly;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050796//regulation of insulin secretion;GO:0006366//transcription from RNA polymerase II promoter;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:2000078//positive regulation of type B pancreatic cell development;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048469//cell maturation;GO:0072560//type B pancreatic cell maturation;GO:0031018//endocrine pancreas development;GO:0060285//cilium-dependent cell motility",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,-
5992,1,1,0,0,0,50,30,26,20,0,1,253,"RFX4;regulatory factor X, 4 (influences HLA class II expression)",GO:0005634//nucleus,"GO:0021516//dorsal spinal cord development;GO:0042384//cilium assembly;GO:0021696//cerebellar cortex morphogenesis;GO:0006351//transcription, DNA-templated;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning;GO:0070613//regulation of protein processing;GO:0021537//telencephalon development;GO:0030901//midbrain development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
5993,83,0,1,0,16,0,0,0,36,130,1,310,"RFX5;regulatory factor X, 5 (influences HLA class II expression)",GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K08061//Primary immunodeficiency;Tuberculosis;Antigen processing and presentation
5994,0,0,0,0,1,0,0,23,11,0,0,0,RFXAP;regulatory factor X-associated protein,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity,K08063//Tuberculosis;Antigen processing and presentation;Primary immunodeficiency
5995,0,0,0,0,0,27,0,0,3,112,4,0,RGR;retinal G protein coupled receptor,GO:0005887//integral component of plasma membrane,GO:0007602//phototransduction;GO:0006935//chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0018298//protein-chromophore linkage;GO:0007601//visual perception;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004950//chemokine receptor activity;GO:0009881//photoreceptor activity;GO:0005515//protein binding,-
5996,21,17,0,0,0,0,0,0,0,0,0,0,RGS1;regulator of G-protein signaling 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0006955//immune response,GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity,K07524//Axon guidance
5997,0,30,0,0,0,0,0,0,0,0,4,0,RGS2;regulator of G-protein signaling 2,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0009898//cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0005737//cytoplasm,GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0010519//negative regulation of phospholipase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0043407//negative regulation of MAP kinase activity;GO:0050873//brown fat cell differentiation;GO:0060087//relaxation of vascular smooth muscle;GO:0007283//spermatogenesis;GO:0031116//positive regulation of microtubule polymerization;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0071877//regulation of adrenergic receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:0060452//positive regulation of cardiac muscle contraction;GO:0007049//cell cycle;GO:0055119//relaxation of cardiac muscle;GO:0006417//regulation of translation,GO:0005096//GTPase activator activity;GO:0005516//calmodulin binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding,K07524//Axon guidance
5998,0,0,1,3,8,15,22,0,10,56,17,0,RGS3;regulator of G-protein signaling 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0000188//inactivation of MAPK activity,GO:0005096//GTPase activator activity,K07524//Axon guidance
5999,0,0,0,0,15,0,0,0,36,0,0,0,RGS4;regulator of G-protein signaling 4,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0000188//inactivation of MAPK activity;GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity;GO:0001965//G-protein alpha-subunit binding;GO:0005516//calmodulin binding,K07524//Axon guidance
60,0,233,4,127,525,33,0,4,0,0,21,0,"ACTB;actin, beta",GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0014069//postsynaptic density;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0030424//axon;GO:0070688//MLL5-L complex;GO:0000790//nuclear chromatin;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043234//protein complex;GO:0005829//cytosol;GO:0030863//cortical cytoskeleton,GO:0021762//substantia nigra development;GO:0051084//'de novo' posttranslational protein folding;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0006928//cellular component movement;GO:0001895//retina homeostasis;GO:0007596//blood coagulation;GO:0045216//cell-cell junction organization;GO:0043044//ATP-dependent chromatin remodeling;GO:0034332//adherens junction organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0045087//innate immune response;GO:0034329//cell junction assembly;GO:0007411//axon guidance;GO:0070527//platelet aggregation;GO:0006325//chromatin organization;GO:0006457//protein folding,GO:0019894//kinesin binding;GO:0005515//protein binding;GO:0050998//nitric-oxide synthase binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005524//ATP binding;GO:0005200//structural constituent of cytoskeleton;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019901//protein kinase binding;GO:0030957//Tat protein binding,K05692//Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Influenza A;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phototransduction - fly;Adherens junction;Viral myocarditis
6000,0,0,0,0,0,0,20,0,19,0,0,262,RGS7;regulator of G-protein signaling 7,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0044292//dendrite terminus;GO:0005834//heterotrimeric G-protein complex,GO:0043547//positive regulation of GTPase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0035556//intracellular signal transduction,GO:0005096//GTPase activator activity;GO:0031681//G-protein beta-subunit binding;GO:0004871//signal transducer activity,K13765//Cocaine addiction;Phototransduction
6001,162,0,0,11,38,10,0,50,0,0,0,0,RGS10;regulator of G-protein signaling 10,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0043197//dendritic spine;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity,K07524//Axon guidance
6002,0,0,0,2,0,0,0,64,31,123,9,0,RGS12;regulator of G-protein signaling 12,GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000794//condensed nuclear chromosome;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0006351//transcription, DNA-templated;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0050790//regulation of catalytic activity;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0035556//intracellular signal transduction",GO:0005057//receptor signaling protein activity;GO:0005096//GTPase activator activity;GO:0030695//GTPase regulator activity,K13765//Cocaine addiction;Phototransduction
6003,0,0,0,0,0,0,0,81,0,0,0,0,RGS13;regulator of G-protein signaling 13,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity,K07524//Axon guidance
6004,62,0,0,0,0,0,0,0,0,0,0,0,RGS16;regulator of G-protein signaling 16,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007601//visual perception;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005516//calmodulin binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding,K07524//Axon guidance
6005,0,0,0,0,0,22,0,0,47,0,0,96,RHAG;Rh-associated glycoprotein,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0015701//bicarbonate transport;GO:0072488//ammonium transmembrane transport;GO:0015670//carbon dioxide transport;GO:0048821//erythrocyte development;GO:0044281//small molecule metabolic process;GO:0006873//cellular ion homeostasis;GO:0060586//multicellular organismal iron ion homeostasis,GO:0008519//ammonium transmembrane transporter activity;GO:0030506//ankyrin binding,-
6006,69,0,0,9,0,0,23,0,52,0,0,0,"RHCE;Rh blood group, CcEe antigens",GO:0005887//integral component of plasma membrane,GO:0072488//ammonium transmembrane transport,GO:0008519//ammonium transmembrane transporter activity,-
6007,53,0,0,15,13,14,22,0,27,0,0,0,"RHD;Rh blood group, D antigen",GO:0005887//integral component of plasma membrane,GO:0072488//ammonium transmembrane transport,GO:0008519//ammonium transmembrane transporter activity,-
6009,0,0,1,52,218,0,0,3,13,0,0,0,RHEB;Ras homolog enriched in brain,GO:0043025//neuronal cell body;GO:0005681//spliceosomal complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0005829//cytosol;GO:0016020//membrane,GO:0007165//signal transduction;GO:0007050//cell cycle arrest;GO:0032008//positive regulation of TOR signaling;GO:0008286//insulin receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019003//GDP binding;GO:0019901//protein kinase binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07208//mTOR signaling pathway;Insulin signaling pathway
6010,161,0,0,3,0,0,17,61,1,0,1,0,RHO;rhodopsin,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0042622//photoreceptor outer segment membrane;GO:0005911//cell-cell junction;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0097381//photoreceptor disc membrane;GO:0030867//rough endoplasmic reticulum membrane;GO:0060342//photoreceptor inner segment membrane;GO:0005887//integral component of plasma membrane,"GO:0006468//protein phosphorylation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0009585//red, far-red light phototransduction;GO:0018298//protein-chromophore linkage;GO:0007603//phototransduction, visible light;GO:0007601//visual perception;GO:0060041//retina development in camera-type eye;GO:0001523//retinoid metabolic process",GO:0004930//G-protein coupled receptor activity;GO:0009881//photoreceptor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016918//retinal binding,K04250//Phototransduction
6011,0,0,0,0,9,15,0,0,0,0,0,0,GRK1;G protein-coupled receptor kinase 1,GO:0097381//photoreceptor disc membrane,"GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0007603//phototransduction, visible light;GO:0060060//post-embryonic retina morphogenesis in camera-type eye;GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008594//photoreceptor cell morphogenesis;GO:0046777//protein autophosphorylation;GO:0042327//positive regulation of phosphorylation;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007601//visual perception",GO:0005524//ATP binding;GO:0050254//rhodopsin kinase activity;GO:0004703//G-protein coupled receptor kinase activity;GO:0004672//protein kinase activity,K00909//Chemokine signaling pathway;Endocytosis;Phototransduction
6013,0,0,0,0,0,0,0,0,40,0,0,0,RLN1;relaxin 1,GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0007565//female pregnancy,GO:0005179//hormone activity,-
6014,0,0,0,0,0,14,0,0,0,0,0,0,RIT2;Ras-like without CAAX 2,GO:0005886//plasma membrane;GO:0005634//nucleus,GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005516//calmodulin binding,-
6016,0,1,0,5,33,11,59,0,72,0,2,0,RIT1;Ras-like without CAAX 1,GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0007265//Ras protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005525//GTP binding;GO:0005516//calmodulin binding;GO:0005515//protein binding,-
6017,0,0,0,13,11,0,0,0,5,0,9,0,RLBP1;retinaldehyde binding protein 1,GO:0005829//cytosol;GO:0044297//cell body,"GO:0007601//visual perception;GO:0006776//vitamin A metabolic process;GO:0006810//transport;GO:0001523//retinoid metabolic process;GO:0007603//phototransduction, visible light",GO:0005215//transporter activity;GO:0005502//11-cis retinal binding;GO:0019841//retinol binding,-
6018,292,0,0,12,18,16,52,0,56,0,1,0,RLF;rearranged L-myc fusion,GO:0005634//nucleus,"GO:0051276//chromosome organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0015074//DNA integration;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
6019,50,0,0,23,4,0,0,0,11,0,0,0,RLN2;relaxin 2,GO:0005576//extracellular region,GO:0007565//female pregnancy,GO:0005179//hormone activity,-
602,0,0,0,0,0,0,0,0,7,0,0,0,BCL3;B-cell CLL/lymphoma 3,GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0032996//Bcl3-Bcl10 complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0033257//Bcl3/NF-kappaB2 complex;GO:0005737//cytoplasm;GO:0043234//protein complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0045082//positive regulation of interleukin-10 biosynthetic process;GO:0042981//regulation of apoptotic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045727//positive regulation of translation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000060//protein import into nucleus, translocation;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0010225//response to UV-C;GO:0042345//regulation of NF-kappaB import into nucleus;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0032729//positive regulation of interferon-gamma production;GO:0030198//extracellular matrix organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042832//defense response to protozoan;GO:0002315//marginal zone B cell differentiation;GO:0051457//maintenance of protein location in nucleus;GO:0002467//germinal center formation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0051101//regulation of DNA binding;GO:0042536//negative regulation of tumor necrosis factor biosynthetic process;GO:0002268//follicular dendritic cell differentiation;GO:0019730//antimicrobial humoral response;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0042742//defense response to bacterium;GO:0009615//response to virus;GO:0045415//negative regulation of interleukin-8 biosynthetic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0042088//T-helper 1 type immune response;GO:0048536//spleen development;GO:0045064//T-helper 2 cell differentiation","GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0030674//protein binding, bridging;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding",-
6023,0,0,0,0,0,0,30,0,3,0,2,19,RMRP;RNA component of mitochondrial RNA processing endoribonuclease,-,-,-,-
60312,0,22,1,0,9,24,21,0,51,0,0,3,AFAP1;actin filament associated protein 1,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005925//focal adhesion,-,GO:0003779//actin binding,-
60313,0,0,0,48,200,1,55,0,32,0,0,0,GPBP1L1;GC-rich promoter binding protein 1-like 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
60314,14,31,0,1,0,0,0,0,21,0,0,0,C12orf10;chromosome 12 open reading frame 10,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0035641//locomotory exploration behavior;GO:0043473//pigmentation,-,-
60343,0,0,0,1,10,10,0,0,9,0,0,0,"FAM3A;family with sequence similarity 3, member A",GO:0005576//extracellular region,-,-,K09666//Other types of O-glycan biosynthesis
6035,0,0,0,0,0,17,0,0,0,0,0,0,"RNASE1;ribonuclease, RNase A family, 1 (pancreatic)",GO:0070062//extracellular vesicular exosome,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0004522//pancreatic ribonuclease activity,-
6036,136,0,0,0,0,17,0,55,0,0,0,0,"RNASE2;ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)",GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0006935//chemotaxis;GO:0006401//RNA catabolic process;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0004540//ribonuclease activity;GO:0004522//pancreatic ribonuclease activity;GO:0003676//nucleic acid binding,K10787//Asthma
6037,0,0,0,0,2,0,0,0,0,0,21,0,"RNASE3;ribonuclease, RNase A family, 3",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006401//RNA catabolic process;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0050830//defense response to Gram-positive bacterium;GO:0019731//antibacterial humoral response;GO:0002227//innate immune response in mucosa,GO:0004540//ribonuclease activity;GO:0004519//endonuclease activity;GO:0003676//nucleic acid binding,K10787//Asthma
6038,0,0,0,3,7,0,0,0,10,0,0,0,"RNASE4;ribonuclease, RNase A family, 4",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0009267//cellular response to starvation;GO:0006379//mRNA cleavage;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0003676//nucleic acid binding;GO:0004522//pancreatic ribonuclease activity,-
60385,78,0,0,7,0,13,0,3,0,0,12,0,TSKS;testis-specific serine kinase substrate,GO:0005814//centriole,GO:0010923//negative regulation of phosphatase activity,GO:0005515//protein binding;GO:0019901//protein kinase binding,-
60386,0,0,0,15,0,17,0,0,3,1,0,596,"SLC25A19;solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0055085//transmembrane transport;GO:0030302//deoxynucleotide transport,GO:0030233//deoxynucleotide transmembrane transporter activity,-
6039,0,0,0,0,0,0,0,0,4,0,0,0,"RNASE6;ribonuclease, RNase A family, k6",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0006401//RNA catabolic process;GO:0090501//RNA phosphodiester bond hydrolysis;GO:0006952//defense response,GO:0003676//nucleic acid binding;GO:0004519//endonuclease activity;GO:0004540//ribonuclease activity,-
604,0,0,1,0,16,25,0,0,37,0,0,342,BCL6;B-cell CLL/lymphoma 6,GO:0005657//replication fork;GO:0005634//nucleus,"GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0043380//regulation of memory T cell differentiation;GO:0048821//erythrocyte development;GO:0030890//positive regulation of B cell proliferation;GO:0032319//regulation of Rho GTPase activity;GO:0032764//negative regulation of mast cell cytokine production;GO:0050727//regulation of inflammatory response;GO:0035024//negative regulation of Rho protein signal transduction;GO:0006351//transcription, DNA-templated;GO:0030036//actin cytoskeleton organization;GO:0051272//positive regulation of cellular component movement;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030308//negative regulation of cell growth;GO:0002634//regulation of germinal center formation;GO:0008285//negative regulation of cell proliferation;GO:0030183//B cell differentiation;GO:0006954//inflammatory response;GO:0050776//regulation of immune response;GO:0000060//protein import into nucleus, translocation;GO:0006974//cellular response to DNA damage stimulus;GO:0001953//negative regulation of cell-matrix adhesion;GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0007266//Rho protein signal transduction;GO:0002467//germinal center formation;GO:0002903//negative regulation of B cell apoptotic process;GO:0002829//negative regulation of type 2 immune response;GO:0000902//cell morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process;GO:0042092//type 2 immune response",GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding;GO:0003682//chromatin binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0005515//protein binding;GO:0046872//metal ion binding,K15618//Transcriptional misregulation in cancer
60401,0,0,0,0,18,0,0,0,35,0,0,0,EDA2R;ectodysplasin A2 receptor,GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046330//positive regulation of JNK cascade;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0009790//embryo development;GO:0030154//cell differentiation;GO:0008544//epidermis development,GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0004872//receptor activity,K05163//Cytokine-cytokine receptor interaction
6041,0,0,0,5,1,0,0,0,21,0,0,0,"RNASEL;ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)",GO:0016363//nuclear matrix;GO:0005739//mitochondrion;GO:0005829//cytosol,"GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006364//rRNA processing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045071//negative regulation of viral genome replication;GO:0006468//protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway;GO:0006397//mRNA processing",GO:0019843//rRNA binding;GO:0004521//endoribonuclease activity;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K01165//Hepatitis C;Herpes simplex infection;Influenza A
60412,123,0,0,30,88,0,0,0,51,0,0,318,EXOC4;exocyst complex component 4,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0035748//myelin sheath abaxonal region;GO:0000145//exocyst;GO:0032584//growth cone membrane,GO:0006904//vesicle docking involved in exocytosis;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0047485//protein N-terminus binding,K06111//Tight junction
60436,0,0,0,0,0,6,16,0,44,0,8,3,TGIF2;TGFB-induced factor homeobox 2,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0060041//retina development in camera-type eye;GO:0006355//regulation of transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0038092//nodal signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0010470//regulation of gastrulation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K15613//Transcriptional misregulation in cancer
60437,0,40,0,7,41,0,0,0,0,100,10,0,CDH26;cadherin 26,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,K06736//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Cell adhesion molecules (CAMs)
6045,0,2,0,8,35,0,0,0,16,0,0,0,RNF2;ring finger protein 2,GO:0071339//MLL1 complex;GO:0000151//ubiquitin ligase complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex;GO:0001739//sex chromatin;GO:0005634//nucleus;GO:0000791//euchromatin;GO:0005730//nucleolus,"GO:0036353//histone H2A-K119 monoubiquitination;GO:0006351//transcription, DNA-templated;GO:0035518//histone H2A monoubiquitination;GO:0000278//mitotic cell cycle;GO:0009948//anterior/posterior axis specification;GO:0001702//gastrulation with mouth forming second;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0071535//RING-like zinc finger domain binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0003682//chromatin binding,-
6046,0,0,0,0,4,0,0,15,0,0,0,9,BRD2;bromodomain containing 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0006334//nucleosome assembly;GO:0016568//chromatin modification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis",GO:0070577//lysine-acetylated histone binding;GO:0003682//chromatin binding;GO:0005515//protein binding,-
60467,0,0,0,0,0,0,35,67,0,18,0,0,"BPESC1;blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding)",-,-,-,-
60468,0,0,14,0,0,23,11,0,45,265,0,75,"BACH2;BTB and CNC homology 1, basic leucine zipper transcription factor 2",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
6047,94,0,0,4,0,0,2,0,8,0,7,0,RNF4;ring finger protein 4,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016605//PML body,"GO:0070979//protein K11-linked ubiquitination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051865//protein autoubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030521//androgen receptor signaling pathway;GO:0090169//regulation of spindle assembly;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0090234//regulation of kinetochore assembly;GO:0006351//transcription, DNA-templated;GO:0085020//protein K6-linked ubiquitination;GO:0046685//response to arsenic-containing substance;GO:0070936//protein K48-linked ubiquitination;GO:0070534//protein K63-linked ubiquitination",GO:0031491//nucleosome binding;GO:0003713//transcription coactivator activity;GO:0016874//ligase activity;GO:0050681//androgen receptor binding;GO:0003677//DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0032184//SUMO polymer binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding,-
60481,0,18,0,77,21,5,26,0,0,0,33,0,ELOVL5;ELOVL fatty acid elongase 5,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,"GO:0036109//alpha-linolenic acid metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0019432//triglyceride biosynthetic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0044255//cellular lipid metabolic process",GO:0005515//protein binding;GO:0009922//fatty acid elongase activity,K10244//Fatty acid elongation;Biosynthesis of unsaturated fatty acids
60482,102,0,0,0,0,0,0,0,41,12,3,0,"SLC5A7;solute carrier family 5 (sodium/choline cotransporter), member 7",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043025//neuronal cell body,"GO:0008219//cell death;GO:0007274//neuromuscular synaptic transmission;GO:0006814//sodium ion transport;GO:0007271//synaptic transmission, cholinergic;GO:0015871//choline transport;GO:0008292//acetylcholine biosynthetic process;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion",GO:0005307//choline:sodium symporter activity;GO:0033265//choline binding;GO:0015220//choline transmembrane transporter activity,K14387//Cholinergic synapse
60484,20,1,1,0,0,12,0,1,0,0,0,0,HAPLN2;hyaluronan and proteoglycan link protein 2,GO:0005578//proteinaceous extracellular matrix,GO:0008065//establishment of blood-nerve barrier;GO:0007155//cell adhesion;GO:0085029//extracellular matrix assembly,GO:0005540//hyaluronic acid binding,-
60485,0,0,0,8,76,0,0,0,16,0,0,0,SAV1;salvador family WW domain containing protein 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0060412//ventricular septum morphogenesis;GO:0001942//hair follicle development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060487//lung epithelial cell differentiation;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0030216//keratinocyte differentiation;GO:0060575//intestinal epithelial cell differentiation;GO:0035329//hippo signaling;GO:0043065//positive regulation of apoptotic process;GO:2000036//regulation of stem cell maintenance,GO:0005515//protein binding,K05631//Tight junction;K05629//Tight junction
60487,0,0,0,12,0,0,0,0,53,0,0,0,TRMT11;tRNA methyltransferase 11 homolog (S. cerevisiae),-,GO:0032259//methylation;GO:0008033//tRNA processing,GO:0008168//methyltransferase activity;GO:0000049//tRNA binding,-
60488,0,14,1,52,200,0,0,0,43,0,0,0,MRPS35;mitochondrial ribosomal protein S35,GO:0005739//mitochondrion;GO:0005763//mitochondrial small ribosomal subunit;GO:0005737//cytoplasm,"GO:0043043//peptide biosynthetic process;GO:0042769//DNA damage response, detection of DNA damage",GO:0044822//poly(A) RNA binding,-
60489,0,1,0,0,23,0,0,0,0,0,0,0,"APOBEC3G;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G",GO:0030895//apolipoprotein B mRNA editing enzyme complex;GO:0000932//cytoplasmic mRNA processing body;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex,GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0016553//base conversion or substitution editing;GO:0048525//negative regulation of viral process;GO:0010529//negative regulation of transposition;GO:0009972//cytidine deamination;GO:0045071//negative regulation of viral genome replication;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0070383//DNA cytosine deamination;GO:0002230//positive regulation of defense response to virus by host,GO:0004126//cytidine deaminase activity;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding;GO:0047844//deoxycytidine deaminase activity,K01500//Atrazine degradation;Microbial metabolism in diverse environments
6049,0,1,0,51,79,0,27,233,15,0,38,0,RNF6;ring finger protein (C3H2C3 type) 6,GO:0030424//axon;GO:0016605//PML body;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane,"GO:0085020//protein K6-linked ubiquitination;GO:0044314//protein K27-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0030517//negative regulation of axon extension;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0060765//regulation of androgen receptor signaling pathway",GO:0050681//androgen receptor binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
60491,0,0,0,0,41,0,0,0,26,198,16,0,NIF3L1;NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae),GO:0005739//mitochondrion;GO:0005737//cytoplasm,"GO:0035998//7,8-dihydroneopterin 3'-triphosphate biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005525//GTP binding;GO:0003934//GTP cyclohydrolase I activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008134//transcription factor binding,-
60492,0,0,76,0,52,19,49,123,17,0,3,0,CCDC90B;coiled-coil domain containing 90B,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
60493,0,0,0,0,0,0,0,0,8,0,0,0,FASTKD5;FAST kinase domains 5,GO:0005739//mitochondrion,GO:0045333//cellular respiration;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0044822//poly(A) RNA binding,-
60494,0,0,0,0,0,16,0,25,11,84,0,0,CCDC81;coiled-coil domain containing 81,-,-,-,-
60495,0,0,0,0,17,0,19,0,44,169,1,0,HPSE2;heparanase 2 (inactive),GO:0005622//intracellular;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix,GO:0006027//glycosaminoglycan catabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process,GO:0030305//heparanase activity;GO:0043395//heparan sulfate proteoglycan binding,K07965//Metabolic pathways;Glycosaminoglycan degradation
60496,0,1,20,9,56,0,0,0,26,0,0,0,AASDHPPT;aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0015939//pantothenate metabolic process;GO:0009059//macromolecule biosynthetic process;GO:0006766//vitamin metabolic process,GO:0000287//magnesium ion binding;GO:0005515//protein binding;GO:0008897//holo-[acyl-carrier-protein] synthase activity,K06133//Pantothenate and CoA biosynthesis
605,0,0,0,0,1,0,0,0,38,0,2,0,BCL7A;B-cell CLL/lymphoma 7A,-,"GO:0045892//negative regulation of transcription, DNA-templated",-,-
6050,0,18,0,0,1,28,61,60,75,0,16,0,RNH1;ribonuclease/angiogenin inhibitor 1,GO:0005737//cytoplasm;GO:0032311//angiogenin-PRI complex;GO:0070062//extracellular vesicular exosome,GO:0006402//mRNA catabolic process;GO:0043086//negative regulation of catalytic activity;GO:0045765//regulation of angiogenesis,GO:0008428//ribonuclease inhibitor activity;GO:0005515//protein binding,K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A
60506,0,0,0,0,0,0,0,86,0,0,0,0,NYX;nyctalopin,GO:0005578//proteinaceous extracellular matrix;GO:0005622//intracellular,GO:0007601//visual perception;GO:0050896//response to stimulus,-,-
60509,1,909,558,1238,2875,0,1,175,105,306,1300,490,AGBL5;ATP/GTP binding protein-like 5,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006508//proteolysis;GO:0035611//protein branching point deglutamylation,GO:0015631//tubulin binding;GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,-
6051,0,37,56,62,223,0,0,0,30,0,0,0,RNPEP;arginyl aminopeptidase (aminopeptidase B),GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0019370//leukotriene biosynthetic process;GO:0006508//proteolysis,GO:0008235//metalloexopeptidase activity;GO:0004301//epoxide hydrolase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
60526,0,1,1,0,10,0,0,33,84,0,0,161,C2orf43;chromosome 2 open reading frame 43,-,-,-,-
60528,0,0,0,7,13,0,3,1,52,70,6,0,ELAC2;elaC ribonuclease Z 2,GO:0005634//nucleus;GO:0005739//mitochondrion,"GO:0072684//mitochondrial tRNA 3'-trailer cleavage, endonucleolytic",GO:0004519//endonuclease activity;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,K00784//RNA transport
60529,112,0,0,0,0,16,0,0,3,0,1,0,ALX4;ALX homeobox 4,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0007517//muscle organ development;GO:0060021//palate development;GO:0048704//embryonic skeletal system morphogenesis;GO:0035115//embryonic forelimb morphogenesis;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0042733//embryonic digit morphogenesis;GO:0048565//digestive tract development;GO:0009791//post-embryonic development;GO:0035116//embryonic hindlimb morphogenesis;GO:0001942//hair follicle development;GO:0042981//regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification",GO:0003677//DNA binding;GO:0071837//HMG box domain binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity,-
60558,176,0,0,11,32,20,0,0,7,0,20,300,GUF1;GUF1 GTPase homolog (S. cerevisiae),GO:0005759//mitochondrial matrix;GO:0005743//mitochondrial inner membrane,GO:0006412//translation;GO:0045727//positive regulation of translation;GO:0006184//GTP catabolic process,GO:0043022//ribosome binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K14536//Ribosome biogenesis in eukaryotes;K03596//Legionellosis
60559,0,31,40,29,43,0,0,174,39,0,39,0,SPCS3;signal peptidase complex subunit 3 homolog (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0005787//signal peptidase complex;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0050796//regulation of insulin secretion;GO:0006465//signal peptide processing;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006508//proteolysis;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,GO:0008233//peptidase activity,K12948//Protein export
60560,0,28,0,0,51,20,53,0,62,0,0,0,"NAA35;N(alpha)-acetyltransferase 35, NatC auxiliary subunit",GO:0005844//polysome;GO:0031417//NatC complex;GO:0005737//cytoplasm,GO:0043066//negative regulation of apoptotic process;GO:0048659//smooth muscle cell proliferation,GO:0005515//protein binding,-
60561,0,0,0,30,39,28,0,0,9,0,0,0,RINT1;RAD50 interactor 1,GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0016192//vesicle-mediated transport;GO:0031572//G2 DNA damage checkpoint;GO:0015031//protein transport,GO:0005515//protein binding,-
6059,6,0,0,20,57,0,0,0,25,0,0,1,"ABCE1;ATP-binding cassette, sub-family E (OABP), member 1",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0006401//RNA catabolic process;GO:0016032//viral process;GO:0043086//negative regulation of catalytic activity;GO:0009615//response to virus;GO:0006200//ATP catabolic process,GO:0008428//ribonuclease inhibitor activity;GO:0051536//iron-sulfur cluster binding;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
60592,0,1,1,19,144,29,0,0,23,0,0,0,SCOC;short coiled-coil protein,GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005802//trans-Golgi network,GO:0016239//positive regulation of macroautophagy,GO:0005515//protein binding,-
60598,0,0,0,0,0,0,5,0,24,0,0,0,"KCNK15;potassium channel, subfamily K, member 15",GO:0016021//integral component of membrane,GO:0034765//regulation of ion transmembrane transport;GO:0071805//potassium ion transmembrane transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,-
606,0,0,0,0,0,0,28,0,18,0,0,0,NBEAP1;neurobeachin pseudogene 1,-,-,-,-
60625,67,1,0,1,4,5,1,0,36,0,9,0,DHX35;DEAH (Asp-Glu-Ala-His) box polypeptide 35,GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome;GO:0006200//ATP catabolic process",GO:0003676//nucleic acid binding;GO:0005524//ATP binding;GO:0008026//ATP-dependent helicase activity,-
60626,0,20,0,7,23,13,0,2,21,0,0,0,RIC8A;RIC8 guanine nucleotide exchange factor A,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0042074//cell migration involved in gastrulation;GO:0043547//positive regulation of GTPase activity;GO:0001701//in utero embryonic development;GO:0008542//visual learning;GO:0071711//basement membrane organization;GO:0001944//vasculature development;GO:0070586//cell-cell adhesion involved in gastrulation,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
606495,67,0,0,0,2,0,75,0,52,0,0,0,CYB5RL;cytochrome b5 reductase-like,-,GO:0055114//oxidation-reduction process,"GO:0004128//cytochrome-b5 reductase activity, acting on NAD(P)H",K00326//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
606551,0,0,0,4,0,0,0,0,0,0,0,0,UBE2MP1;ubiquitin-conjugating enzyme E2M pseudogene 1,-,-,-,K10579//Ubiquitin mediated proteolysis
606553,0,0,0,0,0,3,0,0,0,0,0,0,C8orf49;chromosome 8 open reading frame 49,GO:0016021//integral component of membrane,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
60672,0,0,0,0,0,0,0,0,47,66,0,0,MIIP;migration and invasion inhibitory protein,-,-,-,K03129//Basal transcription factors;Herpes simplex infection;Huntington's disease
606724,0,0,0,0,1,0,0,0,0,0,0,0,"LOC606724;coronin, actin binding protein, 1A pseudogene",-,-,-,K13882//Phagosome;Tuberculosis
60673,0,1,0,0,39,21,0,1,0,0,12,0,ATG101;autophagy related 101,GO:0000407//pre-autophagosomal structure,GO:0000045//autophagic vacuole assembly,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0032403//protein complex binding,-
60675,0,0,0,0,0,0,0,0,20,0,0,0,PROK2;prokineticin 2,GO:0005576//extracellular region,GO:0006954//inflammatory response;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0019233//sensory perception of pain;GO:0045987//positive regulation of smooth muscle contraction;GO:0001525//angiogenesis;GO:0008283//cell proliferation;GO:0006935//chemotaxis;GO:0000187//activation of MAPK activity;GO:0007218//neuropeptide signaling pathway;GO:0007283//spermatogenesis;GO:0007623//circadian rhythm;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process,GO:0001664//G-protein coupled receptor binding,-
60676,0,0,0,0,0,0,15,87,35,0,3,0,PAPPA2;pappalysin 2,GO:0016020//membrane;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0030154//cell differentiation;GO:0060349//bone morphogenesis;GO:0001558//regulation of cell growth;GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding,-
60677,0,0,0,0,0,0,0,0,27,120,13,0,"CELF6;CUGBP, Elav-like family member 6",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing",GO:0003723//RNA binding;GO:0000166//nucleotide binding,-
60678,49,0,30,0,6,0,3,0,48,0,0,0,"EEFSEC;eukaryotic elongation factor, selenocysteine-tRNA-specific",GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0030529//ribonucleoprotein complex,GO:0006184//GTP catabolic process;GO:0001514//selenocysteine incorporation,GO:0043021//ribonucleoprotein complex binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003746//translation elongation factor activity;GO:0035368//selenocysteine insertion sequence binding;GO:0000049//tRNA binding,K02358//Plant-pathogen interaction
60680,107,20,0,0,0,0,0,1,31,301,4,0,"CELF5;CUGBP, Elav-like family member 5",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
60681,0,0,0,0,0,12,0,0,18,0,6,0,"FKBP10;FK506 binding protein 10, 65 kDa",GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0061077//chaperone-mediated protein folding;GO:0000413//protein peptidyl-prolyl isomerization,GO:0005509//calcium ion binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding,-
60682,0,23,1,5,20,13,0,66,0,0,8,0,SMAP1;small ArfGAP 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0032312//regulation of ARF GTPase activity;GO:0043547//positive regulation of GTPase activity;GO:2000369//regulation of clathrin-mediated endocytosis;GO:0045648//positive regulation of erythrocyte differentiation,GO:0030276//clathrin binding;GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12486//Endocytosis
60684,42,1,0,66,81,0,29,0,50,0,0,281,TRAPPC11;trafficking protein particle complex 11,GO:0005794//Golgi apparatus,GO:0016192//vesicle-mediated transport,-,-
60685,7,54,2,6,51,34,22,0,21,0,12,0,"ZFAND3;zinc finger, AN1-type domain 3",-,-,GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
60686,109,0,0,1,12,0,21,0,8,0,14,0,C14orf93;chromosome 14 open reading frame 93,GO:0005576//extracellular region,-,GO:0044822//poly(A) RNA binding,-
607,171,34,1,1,62,1,19,27,105,0,0,1,BCL9;B-cell CLL/lymphoma 9,GO:0005634//nucleus;GO:0005801//cis-Golgi network;GO:0005794//Golgi apparatus,GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0035019//somatic stem cell maintenance;GO:0014908//myotube differentiation involved in skeletal muscle regeneration;GO:0035914//skeletal muscle cell differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0008013//beta-catenin binding,K06237//ECM-receptor interaction;Pathways in cancer;Focal adhesion;Small cell lung cancer;Amoebiasis;Protein digestion and absorption;K06236//Focal adhesion;Protein digestion and absorption;Amoebiasis;ECM-receptor interaction;K14007//Protein processing in endoplasmic reticulum
6079,0,0,0,0,0,0,0,0,40,0,0,0,"SNORD15A;small nucleolar RNA, C/D box 15A",-,-,-,-
608,0,0,0,0,0,12,16,0,17,0,0,0,"TNFRSF17;tumor necrosis factor receptor superfamily, member 17",GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005886//plasma membrane,GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0007275//multicellular organismal development;GO:0002376//immune system process,GO:0004872//receptor activity,K05153//Intestinal immune network for IgA production;Cytokine-cytokine receptor interaction
6090,0,0,0,0,0,0,0,0,11,0,0,0,"RNY5;RNA, Ro-associated Y5",-,-,-,-
6091,258,0,0,0,0,0,142,17,35,0,8,0,"ROBO1;roundabout, axon guidance receptor, homolog 1 (Drosophila)",GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0030673//axolemma;GO:0009986//cell surface,GO:0050925//negative regulation of negative chemotaxis;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050772//positive regulation of axonogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016199//axon midline choice point recognition;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0035385//Roundabout signaling pathway;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0060763//mammary duct terminal end bud growth;GO:0007411//axon guidance;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0007399//nervous system development;GO:0007155//cell adhesion,GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008046//axon guidance receptor activity;GO:0030275//LRR domain binding,K06753//Axon guidance
6092,0,0,0,0,0,7,48,51,52,0,0,0,"ROBO2;roundabout, axon guidance receptor, homolog 2 (Drosophila)",GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0030673//axolemma,GO:0007417//central nervous system development;GO:0007411//axon guidance;GO:0061364//apoptotic process involved in luteolysis;GO:0007420//brain development;GO:0016199//axon midline choice point recognition;GO:0021891//olfactory bulb interneuron development;GO:0031290//retinal ganglion cell axon guidance;GO:0001656//metanephros development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001657//ureteric bud development;GO:0050925//negative regulation of negative chemotaxis;GO:0051964//negative regulation of synapse assembly;GO:0050772//positive regulation of axonogenesis;GO:0032870//cellular response to hormone stimulus,GO:0008046//axon guidance receptor activity;GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K06754//Axon guidance
6093,0,39,0,51,103,25,35,76,25,0,0,1,"ROCK1;Rho-associated, coiled-coil containing protein kinase 1",GO:0005829//cytosol;GO:0005814//centriole;GO:0005886//plasma membrane;GO:0000139//Golgi membrane;GO:0001726//ruffle;GO:0032059//bleb;GO:0005856//cytoskeleton;GO:0030027//lamellipodium,GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007266//Rho protein signal transduction;GO:2000145//regulation of cell motility;GO:0016525//negative regulation of angiogenesis;GO:0006939//smooth muscle contraction;GO:0043524//negative regulation of neuron apoptotic process;GO:0022614//membrane to membrane docking;GO:2000114//regulation of establishment of cell polarity;GO:0045616//regulation of keratinocyte differentiation;GO:0006468//protein phosphorylation;GO:0051893//regulation of focal adhesion assembly;GO:0006915//apoptotic process;GO:0030155//regulation of cell adhesion;GO:0051451//myoblast migration;GO:0007159//leukocyte cell-cell adhesion;GO:0050901//leukocyte tethering or rolling;GO:0051492//regulation of stress fiber assembly;GO:0007411//axon guidance;GO:0032060//bleb assembly;GO:0032956//regulation of actin cytoskeleton organization;GO:0003383//apical constriction;GO:0030036//actin cytoskeleton organization;GO:0051894//positive regulation of focal adhesion assembly,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0017048//Rho GTPase binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K04514//Axon guidance;Chemokine signaling pathway;Salmonella infection;Leukocyte transendothelial migration;Shigellosis;TGF-beta signaling pathway;Regulation of actin cytoskeleton;Wnt signaling pathway;Vascular smooth muscle contraction;Pathogenic Escherichia coli infection;Focal adhesion
6094,0,1,1,0,13,0,0,0,6,0,7,0,ROM1;retinal outer segment membrane protein 1,GO:0042622//photoreceptor outer segment membrane;GO:0005887//integral component of plasma membrane,GO:0007601//visual perception;GO:0007155//cell adhesion;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0061298//retina vasculature development in camera-type eye;GO:0010468//regulation of gene expression,-,K07607//Amyotrophic lateral sclerosis (ALS)
6095,104,0,17,10,5,11,66,41,51,0,12,0,RORA;RAR-related orphan receptor A,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0030522//intracellular receptor signaling pathway;GO:0042753//positive regulation of circadian rhythm;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0019218//regulation of steroid metabolic process;GO:0070328//triglyceride homeostasis;GO:2000188//regulation of cholesterol homeostasis;GO:0042692//muscle cell differentiation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0043401//steroid hormone mediated signaling pathway;GO:0043030//regulation of macrophage activation;GO:0050728//negative regulation of inflammatory response;GO:0010906//regulation of glucose metabolic process;GO:0072539//T-helper 17 cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071456//cellular response to hypoxia;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006805//xenobiotic metabolic process;GO:0021702//cerebellar Purkinje cell differentiation;GO:0006809//nitric oxide biosynthetic process;GO:0032922//circadian regulation of gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0046068//cGMP metabolic process;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0045599//negative regulation of fat cell differentiation;GO:0021930//cerebellar granule cell precursor proliferation;GO:0036315//cellular response to sterol;GO:0008589//regulation of smoothened signaling pathway;GO:0010467//gene expression",GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008013//beta-catenin binding;GO:0008142//oxysterol binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0001223//transcription coactivator binding;GO:0001222//transcription corepressor binding,K08532//Circadian rhythm - mammal
6096,53,8,0,0,127,17,1,0,31,0,27,0,RORB;RAR-related orphan receptor B,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0035881//amacrine cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0060041//retina development in camera-type eye;GO:0030522//intracellular receptor signaling pathway;GO:0048511//rhythmic process;GO:0046548//retinal rod cell development;GO:0042462//eye photoreceptor cell development;GO:0007601//visual perception;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0045668//negative regulation of osteoblast differentiation;GO:0071300//cellular response to retinoic acid;GO:0046549//retinal cone cell development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,K08533//Circadian rhythm - mammal
6097,0,22,0,0,20,15,0,0,18,0,22,0,RORC;RAR-related orphan receptor C,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0030522//intracellular receptor signaling pathway;GO:0042753//positive regulation of circadian rhythm;GO:0042093//T-helper cell differentiation;GO:0019218//regulation of steroid metabolic process;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0048535//lymph node development;GO:0043401//steroid hormone mediated signaling pathway;GO:0010906//regulation of glucose metabolic process;GO:0006468//protein phosphorylation;GO:0033077//T cell differentiation in thymus;GO:0072539//T-helper 17 cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048541//Peyer's patch development;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0006805//xenobiotic metabolic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression;GO:0060612//adipose tissue development;GO:0060850//regulation of transcription involved in cell fate commitment;GO:0036315//cellular response to sterol;GO:0045598//regulation of fat cell differentiation;GO:0010467//gene expression",GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0008142//oxysterol binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001223//transcription coactivator binding,K08534//Circadian rhythm - mammal
6098,0,0,0,0,0,65,41,2,44,11,0,0,"ROS1;ROS proto-oncogene 1 , receptor tyrosine kinase",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0002066//columnar/cuboidal epithelial cell development;GO:0030154//cell differentiation;GO:0010629//negative regulation of gene expression;GO:0016049//cell growth;GO:0007283//spermatogenesis;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0010966//regulation of phosphate transport;GO:0006468//protein phosphorylation;GO:0032006//regulation of TOR signaling;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0008283//cell proliferation,GO:0005515//protein binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding,K05088//MAPK signaling pathway - fly
610,0,0,0,0,4,0,0,0,10,0,0,0,HCN2;hyperpolarization activated cyclic nucleotide-gated potassium channel 2,GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane,GO:0071320//cellular response to cAMP;GO:0042391//regulation of membrane potential;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071321//cellular response to cGMP;GO:0035725//sodium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007267//cell-cell signaling,GO:0005249//voltage-gated potassium channel activity;GO:0005222//intracellular cAMP activated cation channel activity;GO:0042802//identical protein binding;GO:0030552//cAMP binding;GO:0005248//voltage-gated sodium channel activity,-
6100,0,28,18,28,0,0,0,0,24,0,0,0,RP9;retinitis pigmentosa 9 (autosomal dominant),GO:0005634//nucleus;GO:0005785//signal recognition particle receptor complex,GO:0008380//RNA splicing;GO:0050890//cognition,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
6101,0,0,0,0,0,40,0,0,13,0,10,0,RP1;retinitis pigmentosa 1 (autosomal dominant),GO:0032391//photoreceptor connecting cilium;GO:0005874//microtubule;GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0005930//axoneme;GO:0005875//microtubule associated complex,"GO:0035082//axoneme assembly;GO:0007601//visual perception;GO:0035845//photoreceptor cell outer segment organization;GO:0046548//retinal rod cell development;GO:0035556//intracellular signal transduction;GO:0046549//retinal cone cell development;GO:0007603//phototransduction, visible light;GO:0042461//photoreceptor cell development;GO:0045494//photoreceptor cell maintenance;GO:0071482//cellular response to light stimulus",GO:0005515//protein binding;GO:0008017//microtubule binding,-
6102,0,20,0,4,4,0,0,0,0,0,18,0,RP2;retinitis pigmentosa 2 (X-linked recessive),GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0036064//ciliary basal body;GO:0005814//centriole,GO:0043547//positive regulation of GTPase activity;GO:0007601//visual perception;GO:0006183//GTP biosynthetic process;GO:0006241//CTP biosynthetic process;GO:0015031//protein transport;GO:0007010//cytoskeleton organization;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006228//UTP biosynthetic process;GO:0007023//post-chaperonin tubulin folding pathway;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006457//protein folding;GO:0000902//cell morphogenesis,GO:0005525//GTP binding;GO:0005096//GTPase activator activity;GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity;GO:0003779//actin binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding,K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
6103,0,0,0,5,67,0,5,0,16,0,0,0,RPGR;retinitis pigmentosa GTPase regulator,GO:0005813//centrosome;GO:0001750//photoreceptor outer segment;GO:0005794//Golgi apparatus;GO:0036126//sperm flagellum;GO:0036064//ciliary basal body,GO:0043547//positive regulation of GTPase activity;GO:0007601//visual perception;GO:0042384//cilium assembly;GO:0042073//intraciliary transport;GO:0042462//eye photoreceptor cell development;GO:0006886//intracellular protein transport;GO:0050896//response to stimulus,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity,K10615//Ubiquitin mediated proteolysis;K10614//Ubiquitin mediated proteolysis
611,0,0,0,0,0,0,0,13,0,0,21,0,"OPN1SW;opsin 1 (cone pigments), short-wave-sensitive",GO:0042622//photoreceptor outer segment membrane;GO:0005887//integral component of plasma membrane,"GO:0007601//visual perception;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007602//phototransduction;GO:0001523//retinoid metabolic process;GO:0018298//protein-chromophore linkage;GO:0007603//phototransduction, visible light",GO:0004930//G-protein coupled receptor activity;GO:0004872//receptor activity;GO:0009881//photoreceptor activity,-
6117,0,69,1,53,122,0,30,53,23,140,0,0,"RPA1;replication protein A1, 70kDa",GO:0005634//nucleus;GO:0000800//lateral element;GO:0005662//DNA replication factor A complex;GO:0016605//PML body;GO:0005730//nucleolus;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus;GO:0005654//nucleoplasm,"GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0030097//hemopoiesis;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006284//base-excision repair;GO:0006298//mismatch repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0007126//meiotic nuclear division;GO:0000723//telomere maintenance;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0006261//DNA-dependent DNA replication;GO:0048873//homeostasis of number of cells within a tissue;GO:0000730//DNA recombinase assembly;GO:0008284//positive regulation of cell proliferation;GO:0001701//in utero embryonic development",GO:0003682//chromatin binding;GO:0003684//damaged DNA binding;GO:0003697//single-stranded DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K07466//DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;Fanconi anemia pathway
6118,0,5,0,13,56,0,0,0,46,0,0,0,"RPA2;replication protein A2, 32kDa","GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region;GO:0005662//DNA replication factor A complex;GO:0016605//PML body;GO:0035861//site of double-strand break;GO:0005730//nucleolus","GO:0010569//regulation of double-strand break repair via homologous recombination;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication;GO:0006298//mismatch repair;GO:0006284//base-excision repair;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000724//double-strand break repair via homologous recombination;GO:0000722//telomere maintenance via recombination;GO:2000001//regulation of DNA damage checkpoint;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006289//nucleotide-excision repair;GO:0000730//DNA recombinase assembly;GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0031571//mitotic G1 DNA damage checkpoint",GO:0003684//damaged DNA binding;GO:0047485//protein N-terminus binding;GO:0019899//enzyme binding;GO:0019903//protein phosphatase binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0003697//single-stranded DNA binding,K10739//Mismatch repair;Homologous recombination;Fanconi anemia pathway;DNA replication;Nucleotide excision repair
6119,146,0,0,8,40,21,0,0,19,0,0,0,"RPA3;replication protein A3, 14kDa",GO:0005662//DNA replication factor A complex;GO:0005654//nucleoplasm,"GO:0006297//nucleotide-excision repair, DNA gap filling;GO:0000723//telomere maintenance;GO:0000730//DNA recombinase assembly;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006289//nucleotide-excision repair;GO:0006271//DNA strand elongation involved in DNA replication;GO:0000724//double-strand break repair via homologous recombination;GO:0006283//transcription-coupled nucleotide-excision repair;GO:0000722//telomere maintenance via recombination;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0006284//base-excision repair;GO:0006298//mismatch repair;GO:0000082//G1/S transition of mitotic cell cycle;GO:0042127//regulation of cell proliferation;GO:0007346//regulation of mitotic cell cycle;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0032201//telomere maintenance via semi-conservative replication",GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0003684//damaged DNA binding,K10740//DNA replication;Nucleotide excision repair;Homologous recombination;Mismatch repair;Fanconi anemia pathway
6120,131,17,0,50,44,62,31,0,23,0,0,0,RPE;ribulose-5-phosphate-3-epimerase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0006098//pentose-phosphate shunt;GO:0005975//carbohydrate metabolic process,GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0004750//ribulose-phosphate 3-epimerase activity,K01783//Pentose and glucuronate interconversions;Metabolic pathways;Pentose phosphate pathway;Purine metabolism;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms;Pyrimidine metabolism;Biosynthesis of secondary metabolites
6121,0,0,0,0,0,0,22,70,39,172,0,0,RPE65;retinal pigment epithelium-specific protein 65kDa,GO:0031090//organelle membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum,"GO:0071257//cellular response to electrical stimulus;GO:0007603//phototransduction, visible light;GO:0001895//retina homeostasis;GO:0050908//detection of light stimulus involved in visual perception;GO:0060042//retina morphogenesis in camera-type eye;GO:0042574//retinal metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0042572//retinol metabolic process;GO:0006776//vitamin A metabolic process;GO:0001523//retinoid metabolic process;GO:0007601//visual perception;GO:0007468//regulation of rhodopsin gene expression","GO:0004744//retinal isomerase activity;GO:0052885//all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity;GO:0046872//metal ion binding;GO:0052884//all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity",K11158//Retinol metabolism
6122,0,578,8,250,582,0,6,86,42,0,6,0,RPL3;ribosomal protein L3,GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0071353//cellular response to interleukin-4;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02925//Ribosome
6123,0,0,0,0,1,0,35,0,0,0,0,0,RPL3L;ribosomal protein L3-like,GO:0016020//membrane;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022625//cytosolic large ribosomal subunit,"GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome,K02925//Ribosome
6124,0,325,7,308,1062,0,0,0,1,0,0,0,RPL4;ribosomal protein L4,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02930//Ribosome
6125,0,83,5,102,435,0,5,0,17,0,12,162,RPL5;ribosomal protein L5,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis;GO:0016032//viral process",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding;GO:0008097//5S rRNA binding,K02932//Ribosome
6128,1,161,1,188,543,0,0,8,1,0,0,0,RPL6;ribosomal protein L6,GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003677//DNA binding,K02934//Ribosome
6129,0,37,72,121,384,0,0,0,20,0,0,0,RPL7;ribosomal protein L7,GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0016032//viral process;GO:0042273//ribosomal large subunit biogenesis;GO:0006364//rRNA processing;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity,K02937//Ribosome
613,80,0,0,0,3,18,5,15,5,67,1,0,BCR;breakpoint cluster region,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0043234//protein complex,GO:0007165//signal transduction;GO:0050766//positive regulation of phagocytosis;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0050728//negative regulation of inflammatory response;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0042472//inner ear morphogenesis;GO:0043314//negative regulation of neutrophil degranulation;GO:0030036//actin cytoskeleton organization;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0032855//positive regulation of Rac GTPase activity;GO:0032496//response to lipopolysaccharide;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007420//brain development;GO:0051726//regulation of cell cycle;GO:0030336//negative regulation of cell migration;GO:0050885//neuromuscular process controlling balance,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005096//GTPase activator activity;GO:0004713//protein tyrosine kinase activity;GO:0030675//Rac GTPase activator activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0016301//kinase activity,K08878//Chronic myeloid leukemia;Pathways in cancer
6130,0,460,10,263,526,0,0,1,40,1,15,0,RPL7A;ribosomal protein L7a,GO:0042788//polysomal ribosome;GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol,"GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016032//viral process",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02936//Ribosome
613037,1,0,0,0,0,7,0,0,1,0,1,0,LOC613037;nuclear pore complex interacting protein pseudogene,-,-,-,K10413//Salmonella infection;Vasopressin-regulated water reabsorption;Phagosome;K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
6132,0,64,5,22,182,0,27,1,7,0,0,0,RPL8;ribosomal protein L8,GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding;GO:0019843//rRNA binding,K02938//Ribosome
613210,0,0,0,0,0,0,1,0,0,0,0,0,"DEFB136;defensin, beta 136",GO:0005576//extracellular region,GO:0042742//defense response to bacterium,-,-
613212,0,0,0,0,0,0,0,0,48,0,0,0,CTXN3;cortexin 3,GO:0016021//integral component of membrane,-,-,-
6133,28,183,1,53,289,0,0,0,17,1,0,0,RPL9;ribosomal protein L9,GO:0005840//ribosome;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,"GO:0016032//viral process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding;GO:0019843//rRNA binding,K02940//Ribosome
6134,0,299,43,295,814,18,51,69,14,0,147,0,RPL10;ribosomal protein L10,GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit,"GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02866//Ribosome
6135,54,140,3,289,579,0,0,0,19,0,0,0,RPL11;ribosomal protein L11,GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005829//cytosol,"GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0034504//protein localization to nucleus;GO:0006413//translational initiation;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0042273//ribosomal large subunit biogenesis;GO:0006364//rRNA processing;GO:0006605//protein targeting;GO:0010467//gene expression;GO:0006412//translation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding;GO:0003723//RNA binding,K02868//Ribosome
6136,0,96,0,85,501,0,2,0,1,0,44,0,RPL12;ribosomal protein L12,GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02870//Ribosome
6137,0,169,1,107,396,1,0,3,33,0,9,0,RPL13;ribosomal protein L13,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0022626//cytosolic ribosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005829//cytosol,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02873//Ribosome
6138,0,374,58,297,995,1,127,0,125,0,68,0,RPL15;ribosomal protein L15,GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005840//ribosome,"GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016032//viral process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02877//Ribosome
6139,0,48,0,79,194,0,0,0,0,0,0,22,RPL17;ribosomal protein L17,GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02880//Ribosome
6141,0,155,25,118,231,1,0,22,2,0,0,0,RPL18;ribosomal protein L18,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome,K02883//Ribosome
6142,0,14,0,10,60,0,0,0,22,0,0,0,RPL18A;ribosomal protein L18a,GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0005829//cytosol,"GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016032//viral process;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02882//Ribosome
6143,0,101,20,66,360,0,0,0,0,1,2,0,RPL19;ribosomal protein L19,GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02885//Ribosome
6146,0,293,3,315,1193,18,1,0,32,0,13,0,RPL22;ribosomal protein L22,GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,"GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0016032//viral process;GO:0046632//alpha-beta T cell differentiation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008201//heparin binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02891//Ribosome
6147,0,88,7,86,370,0,24,0,0,0,0,0,RPL23A;ribosomal protein L23a,GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0031932//TORC2 complex,"GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0008283//cell proliferation;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0019843//rRNA binding,K02893//Ribosome
6150,0,0,0,0,0,0,0,0,0,153,0,0,MRPL23;mitochondrial ribosomal protein L23,GO:0005730//nucleolus;GO:0005762//mitochondrial large ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0003735//structural constituent of ribosome,-
6152,14,124,2,34,340,1,8,0,0,0,20,0,RPL24;ribosomal protein L24,GO:0022625//cytosolic large ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0000027//ribosomal large subunit assembly;GO:0006414//translational elongation;GO:0016032//viral process;GO:0060041//retina development in camera-type eye;GO:0044267//cellular protein metabolic process;GO:0010458//exit from mitosis;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0019058//viral life cycle;GO:0031290//retinal ganglion cell axon guidance;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0007093//mitotic cell cycle checkpoint;GO:0010467//gene expression;GO:0021554//optic nerve development;GO:0006412//translation",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02896//Ribosome
6154,0,11,1,49,182,0,31,0,0,0,0,0,RPL26;ribosomal protein L26,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0006364//rRNA processing;GO:0042273//ribosomal large subunit biogenesis",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02898//Ribosome
6155,0,65,0,90,155,0,0,0,0,0,0,0,RPL27;ribosomal protein L27,GO:0005925//focal adhesion;GO:0005840//ribosome;GO:0005829//cytosol;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit,"GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02901//Ribosome
6156,0,0,0,0,0,0,22,0,0,0,0,0,RPL30;ribosomal protein L30,GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,"GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003723//RNA binding,K02908//Ribosome
6157,1,132,28,69,428,0,3,0,10,0,0,0,RPL27A;ribosomal protein L27a,GO:0005829//cytosol;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit,"GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02900//Ribosome
6158,21,55,0,2,57,43,0,0,24,0,0,0,RPL28;ribosomal protein L28,GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0044297//cell body;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0005829//cytosol;GO:0016020//membrane,"GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02903//Ribosome
6159,0,94,2,50,196,0,0,0,0,0,0,0,RPL29;ribosomal protein L29,GO:0005829//cytosol;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit,"GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016032//viral process;GO:0010467//gene expression;GO:0007566//embryo implantation;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0008201//heparin binding;GO:0044822//poly(A) RNA binding,K02905//Ribosome
6160,0,0,0,79,134,0,0,0,22,0,0,0,RPL31;ribosomal protein L31,GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K02910//Ribosome
6161,75,1,1,90,241,0,0,0,13,139,0,0,RPL32;ribosomal protein L32,GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0005829//cytosol,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02912//Ribosome
6164,0,110,2,39,141,0,0,0,5,0,18,0,RPL34;ribosomal protein L34,GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02915//Ribosome
6165,0,118,0,14,175,0,0,0,14,0,12,0,RPL35A;ribosomal protein L35a,GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0042273//ribosomal large subunit biogenesis;GO:0006364//rRNA processing;GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination",GO:0000049//tRNA binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02917//Ribosome
6166,0,0,1,8,49,0,0,0,9,0,0,0,RPL36AL;ribosomal protein L36a-like,GO:0005840//ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K02929//Ribosome
6167,0,3,0,11,51,0,0,0,0,0,0,0,RPL37;ribosomal protein L37,GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination",GO:0003735//structural constituent of ribosome;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0019843//rRNA binding,K02922//Ribosome
6168,0,83,2,75,208,0,16,0,0,0,0,0,RPL37A;ribosomal protein L37a,GO:0022625//cytosolic large ribosomal subunit;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,"GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0003735//structural constituent of ribosome,K02921//Ribosome
6169,0,77,1,20,73,0,0,0,7,0,0,0,RPL38;ribosomal protein L38,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit,"GO:0042474//middle ear morphogenesis;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0001501//skeletal system development;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0048318//axial mesoderm development;GO:0007605//sensory perception of sound;GO:0001503//ossification;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0006412//translation;GO:0010467//gene expression;GO:0006417//regulation of translation",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02923//Ribosome
617,0,0,0,0,2,0,29,0,17,0,23,0,BCS1L;BC1 (ubiquinol-cytochrome c reductase) synthesis-like,GO:0005750//mitochondrial respiratory chain complex III;GO:0005739//mitochondrion,GO:0007005//mitochondrion organization;GO:0033617//mitochondrial respiratory chain complex IV assembly;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0034551//mitochondrial respiratory chain complex III assembly,GO:0005524//ATP binding;GO:0005515//protein binding,-
6170,0,64,0,83,22,0,0,0,0,0,0,0,RPL39;ribosomal protein L39,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002227//innate immune response in mucosa;GO:0019058//viral life cycle;GO:0010467//gene expression;GO:0019731//antibacterial humoral response;GO:0006412//translation;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0050830//defense response to Gram-positive bacterium;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02924//Ribosome
6171,0,38,2,17,64,0,1,0,0,1,0,0,RPL41;ribosomal protein L41,GO:0022625//cytosolic large ribosomal subunit;GO:0005829//cytosol,"GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K01511//Pyrimidine metabolism;Purine metabolism
6175,0,241,6,58,333,0,5,1,15,0,1,109,"RPLP0;ribosomal protein, large, P0",GO:0005634//nucleus;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome,"GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0042254//ribosome biogenesis;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,K02941//Ribosome
6176,92,0,1,1,32,0,0,0,0,0,0,0,"RPLP1;ribosomal protein, large, P1",GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion,"GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0003723//RNA binding,K02942//Ribosome
618,1,0,0,0,0,0,0,41,7,0,5,0,BCYRN1;brain cytoplasmic RNA 1,-,-,-,-
6181,0,16,0,3,25,0,0,0,0,0,0,0,"RPLP2;ribosomal protein, large, P2",GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005829//cytosol;GO:0022625//cytosolic large ribosomal subunit,"GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02943//Ribosome
6182,0,1,0,0,0,3,0,0,15,0,0,0,MRPL12;mitochondrial ribosomal protein L12,GO:0005762//mitochondrial large ribosomal subunit;GO:0005739//mitochondrion,"GO:0006390//transcription from mitochondrial promoter;GO:0006412//translation;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0003723//RNA binding,K13577//Proximal tubule bicarbonate reclamation
6183,0,0,0,0,1,0,3,0,0,0,33,0,MRPS12;mitochondrial ribosomal protein S12,GO:0015935//small ribosomal subunit;GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02973//Ribosome
6184,68,19,31,2,37,28,1,0,15,0,10,0,RPN1;ribophorin I,GO:0005789//endoplasmic reticulum membrane;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex;GO:0042470//melanosome,GO:0006412//translation;GO:0006464//cellular protein modification process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12666//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis;Protein processing in endoplasmic reticulum
6185,0,1,0,34,38,21,0,0,8,50,16,0,RPN2;ribophorin II,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005791//rough endoplasmic reticulum;GO:0008250//oligosaccharyltransferase complex;GO:0000421//autophagic vacuole membrane;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0043687//post-translational protein modification;GO:0007568//aging;GO:0006464//cellular protein modification process;GO:0042493//response to drug;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0043022//ribosome binding,K12667//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
6187,0,31,1,24,76,0,0,1,0,0,10,0,RPS2;ribosomal protein S2,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus,"GO:0044267//cellular protein metabolic process;GO:0051347//positive regulation of transferase activity;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process",GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0019899//enzyme binding,K02981//Ribosome
6188,0,330,106,172,436,10,16,0,30,0,2,0,RPS3;ribosomal protein S3,GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0071159//NF-kappaB complex;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit,"GO:0006412//translation;GO:0045738//negative regulation of DNA repair;GO:0010467//gene expression;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0019058//viral life cycle;GO:1902546//positive regulation of DNA N-glycosylase activity;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0002181//cytoplasmic translation;GO:0044267//cellular protein metabolic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0016032//viral process;GO:0006974//cellular response to DNA damage stimulus;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006414//translational elongation",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003684//damaged DNA binding;GO:0051018//protein kinase A binding;GO:0019901//protein kinase binding;GO:0003735//structural constituent of ribosome;GO:0003729//mRNA binding;GO:0051536//iron-sulfur cluster binding;GO:0019899//enzyme binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0051059//NF-kappaB binding,K02985//Ribosome
6189,90,315,5,455,1423,1,0,0,4,0,0,0,RPS3A;ribosomal protein S3A,GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome,"GO:0030154//cell differentiation;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0002181//cytoplasmic translation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0006412//translation;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02984//Ribosome
6191,94,439,28,407,1319,0,0,0,14,0,12,0,"RPS4X;ribosomal protein S4, X-linked",GO:0022627//cytosolic small ribosomal subunit;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0005840//ribosome;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005844//polysome;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex,"GO:0006412//translation;GO:0010467//gene expression;GO:0008284//positive regulation of cell proliferation;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0007275//multicellular organismal development;GO:0016032//viral process;GO:0045727//positive regulation of translation;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0019843//rRNA binding,K02987//Ribosome
619189,707,3628,1880,2986,4039,1,51,1083,222,4,4458,7,SERINC4;serine incorporator 4,GO:0016021//integral component of membrane,GO:0008654//phospholipid biosynthetic process,-,-
619190,1,0,0,24,19,9,0,74,25,0,0,0,FDPSP2;farnesyl diphosphate synthase pseudogene 2,-,-,-,K00787//Metabolic pathways;Terpenoid backbone biosynthesis;HTLV-I infection;Biosynthesis of secondary metabolites;Influenza A
6192,0,23,1,52,215,0,0,0,0,0,0,0,"RPS4Y1;ribosomal protein S4, Y-linked 1",GO:0016020//membrane;GO:0005829//cytosol;GO:0005844//polysome;GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus,"GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0007275//multicellular organismal development;GO:0010467//gene expression",GO:0003723//RNA binding;GO:0019843//rRNA binding;GO:0003735//structural constituent of ribosome,K02987//Ribosome
619207,0,0,0,0,0,3,0,0,18,0,0,0,SCART1;scavenger receptor protein family member,GO:0016021//integral component of membrane,GO:0006898//receptor-mediated endocytosis;GO:0002376//immune system process,GO:0005044//scavenger receptor activity,-
619208,0,0,0,4,35,28,11,0,54,0,0,0,"FAM229B;family with sequence similarity 229, member B",-,-,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
619279,40,76,0,56,379,1,0,124,49,0,43,142,ZNF704;zinc finger protein 704,-,-,GO:0046872//metal ion binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
6193,0,0,0,21,22,1,0,30,0,0,1,0,RPS5;ribosomal protein S5,GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit,"GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006450//regulation of translational fidelity;GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K02989//Ribosome
619343,0,0,0,0,0,0,11,0,0,0,0,0,ERICH1-AS1;ERICH1 antisense RNA 1,-,-,-,-
619373,0,0,0,0,0,16,0,37,36,0,0,0,MBOAT4;membrane bound O-acyltransferase domain containing 4,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0018191//peptidyl-serine octanoylation;GO:0044267//cellular protein metabolic process,GO:0016412//serine O-acyltransferase activity,K13517//Glycerophospholipid metabolism;Glycerolipid metabolism;Metabolic pathways
6194,0,558,25,312,1113,0,1,0,19,0,6,0,RPS6;ribosomal protein S6,GO:0044297//cell body;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0030425//dendrite;GO:0005844//polysome;GO:0022627//cytosolic small ribosomal subunit;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0015935//small ribosomal subunit,"GO:0006412//translation;GO:0002309//T cell proliferation involved in immune response;GO:0001890//placenta development;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0042593//glucose homeostasis;GO:0006364//rRNA processing;GO:0007093//mitotic cell cycle checkpoint;GO:0000028//ribosomal small subunit assembly;GO:0042274//ribosomal small subunit biogenesis;GO:0006924//activation-induced cell death of T cells;GO:0019058//viral life cycle;GO:0022605//oogenesis stage;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0048821//erythrocyte development;GO:0031929//TOR signaling;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0008286//insulin receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0044267//cellular protein metabolic process;GO:0033077//T cell differentiation in thymus;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007369//gastrulation;GO:0016071//mRNA metabolic process;GO:0007067//mitotic nuclear division;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019901//protein kinase binding,K02991//Ribosome;mTOR signaling pathway;Insulin signaling pathway
619455,0,0,0,0,0,0,21,0,2,0,0,0,SPANXA2-OT1;SPANXA2 overlapping transcript 1,-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
6195,0,0,1,0,52,27,0,41,50,0,9,0,"RPS6KA1;ribosomal protein S6 kinase, 90kDa, polypeptide 1",GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007049//cell cycle;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043555//regulation of translation in response to stress;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007411//axon guidance;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0030307//positive regulation of cell growth;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0007165//signal transduction;GO:2000491//positive regulation of hepatic stellate cell activation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0045597//positive regulation of cell differentiation,GO:0000287//magnesium ion binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity,K04373//Long-term potentiation;Progesterone-mediated oocyte maturation;MAPK signaling pathway;Oocyte meiosis;mTOR signaling pathway;Neurotrophin signaling pathway
619518,0,0,0,0,0,0,0,0,17,0,0,0,SSBP3-AS1;SSBP3 antisense RNA 1,GO:0005576//extracellular region,-,-,-
619552,0,0,0,0,0,0,0,0,10,0,0,0,MIR483;microRNA 483,-,-,-,-
619556,0,0,0,0,0,8,0,0,0,0,0,0,MIR455;microRNA 455,-,-,-,-
6196,8,1,0,50,33,5,8,0,70,38,17,0,"RPS6KA2;ribosomal protein S6 kinase, 90kDa, polypeptide 2",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0043065//positive regulation of apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0007268//synaptic transmission;GO:0018105//peptidyl-serine phosphorylation;GO:0007165//signal transduction;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0060047//heart contraction;GO:0007411//axon guidance;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0002035//brain renin-angiotensin system;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0071322//cellular response to carbohydrate stimulus;GO:0070613//regulation of protein processing;GO:0045786//negative regulation of cell cycle;GO:0035556//intracellular signal transduction;GO:0034146//toll-like receptor 5 signaling pathway;GO:0010628//positive regulation of gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0001556//oocyte maturation;GO:0007507//heart development;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045835//negative regulation of meiosis;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0010659//cardiac muscle cell apoptotic process,GO:0005515//protein binding;GO:0004711//ribosomal protein S6 kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,K04373//Long-term potentiation;Progesterone-mediated oocyte maturation;Oocyte meiosis;mTOR signaling pathway;Neurotrophin signaling pathway;MAPK signaling pathway
6197,0,292,0,190,447,0,25,0,75,0,0,1,"RPS6KA3;ribosomal protein S6 kinase, 90kDa, polypeptide 3",GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0043620//regulation of DNA-templated transcription in response to stress;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0030307//positive regulation of cell growth;GO:0034166//toll-like receptor 10 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0007417//central nervous system development;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007411//axon guidance;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043555//regulation of translation in response to stress;GO:0045087//innate immune response;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007049//cell cycle;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0001501//skeletal system development;GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction,GO:0000287//magnesium ion binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K04373//Progesterone-mediated oocyte maturation;Long-term potentiation;MAPK signaling pathway;Neurotrophin signaling pathway;mTOR signaling pathway;Oocyte meiosis
6198,0,0,0,5,73,26,0,0,60,0,0,0,"RPS6KB1;ribosomal protein S6 kinase, 70kDa, polypeptide 1",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0043005//neuron projection;GO:0045202//synapse;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm,GO:0014732//skeletal muscle atrophy;GO:0007165//signal transduction;GO:0048633//positive regulation of skeletal muscle tissue growth;GO:0007616//long-term memory;GO:0045727//positive regulation of translation;GO:0003009//skeletal muscle contraction;GO:0071363//cellular response to growth factor stimulus;GO:0006468//protein phosphorylation;GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0007584//response to nutrient;GO:0034612//response to tumor necrosis factor;GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0051384//response to glucocorticoid;GO:0042493//response to drug;GO:0007281//germ cell development;GO:0045471//response to ethanol;GO:0033574//response to testosterone;GO:0032496//response to lipopolysaccharide;GO:0009408//response to heat;GO:0009611//response to wounding;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016477//cell migration;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007568//aging;GO:0045948//positive regulation of translational initiation;GO:0008286//insulin receptor signaling pathway;GO:0043201//response to leucine;GO:0046324//regulation of glucose import;GO:0014911//positive regulation of smooth muscle cell migration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0031929//TOR signaling;GO:0009636//response to toxic substance;GO:0045931//positive regulation of mitotic cell cycle;GO:0043491//protein kinase B signaling;GO:0009749//response to glucose;GO:0048015//phosphatidylinositol-mediated signaling;GO:0043066//negative regulation of apoptotic process;GO:0033762//response to glucagon,GO:0005524//ATP binding;GO:0042277//peptide binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004711//ribosomal protein S6 kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,K04688//Fc gamma R-mediated phagocytosis;ErbB signaling pathway;TGF-beta signaling pathway;mTOR signaling pathway;Acute myeloid leukemia;Insulin signaling pathway
6199,0,17,1,0,1,0,26,0,13,0,1,0,"RPS6KB2;ribosomal protein S6 kinase, 70kDa, polypeptide 2",GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006468//protein phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006412//translation;GO:0007165//signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045948//positive regulation of translational initiation;GO:0045087//innate immune response;GO:0043491//protein kinase B signaling,GO:0004711//ribosomal protein S6 kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0042277//peptide binding,K04688//Acute myeloid leukemia;Insulin signaling pathway;mTOR signaling pathway;TGF-beta signaling pathway;Fc gamma R-mediated phagocytosis;ErbB signaling pathway
6201,0,77,0,113,211,0,0,0,21,0,10,0,RPS7;ribosomal protein S7,GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0032040//small-subunit processome;GO:0005815//microtubule organizing center;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005840//ribosome;GO:0030686//90S preribosome;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane,"GO:0044267//cellular protein metabolic process;GO:0002181//cytoplasmic translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0006414//translational elongation;GO:0016032//viral process;GO:0010467//gene expression;GO:0006412//translation;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006364//rRNA processing;GO:0042274//ribosomal small subunit biogenesis",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02993//Ribosome
6202,0,224,9,162,581,0,0,1,0,0,6,0,RPS8;ribosomal protein S8,GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0070062//extracellular vesicular exosome,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02995//Ribosome
6203,6,70,6,43,188,20,52,5,11,0,2,0,RPS9;ribosomal protein S9,GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005840//ribosome;GO:0005829//cytosol;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm,"GO:0016032//viral process;GO:0008284//positive regulation of cell proliferation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0006417//regulation of translation;GO:0044267//cellular protein metabolic process",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0045182//translation regulator activity;GO:0019843//rRNA binding,K02997//Ribosome
6204,0,0,0,1,0,0,0,0,0,0,0,0,RPS10;ribosomal protein S10,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0022627//cytosolic small ribosomal subunit,"GO:0016032//viral process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02947//Ribosome
6205,0,127,2,21,119,1,19,0,0,0,0,0,RPS11;ribosomal protein S11,GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005840//ribosome;GO:0005829//cytosol,"GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0016032//viral process",GO:0019843//rRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,K02949//Ribosome
6206,0,32,1,135,232,0,0,0,31,0,0,0,RPS12;ribosomal protein S12,GO:0022627//cytosolic small ribosomal subunit;GO:0005829//cytosol;GO:0016020//membrane,"GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016032//viral process;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,K02951//Ribosome
6207,0,82,0,100,157,0,0,0,19,0,0,0,RPS13;ribosomal protein S13,GO:0005829//cytosol;GO:0005840//ribosome;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit;GO:0005634//nucleus;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,"GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0033119//negative regulation of RNA splicing;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003729//mRNA binding;GO:0003735//structural constituent of ribosome,K02953//Ribosome
6208,0,73,5,71,375,0,0,0,0,0,0,0,RPS14;ribosomal protein S14,GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005829//cytosol,"GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0030490//maturation of SSU-rRNA;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006412//translation;GO:0010467//gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006417//regulation of translation;GO:0030218//erythrocyte differentiation;GO:0000028//ribosomal small subunit assembly;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0048027//mRNA 5'-UTR binding;GO:0045182//translation regulator activity;GO:0003723//RNA binding,K02955//Ribosome
6209,0,70,0,7,41,0,18,0,1,0,0,0,RPS15;ribosomal protein S15,GO:0016020//membrane;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0022627//cytosolic small ribosomal subunit;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006364//rRNA processing;GO:0042274//ribosomal small subunit biogenesis;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000056//ribosomal small subunit export from nucleus;GO:0006412//translation;GO:0010467//gene expression;GO:0016032//viral process;GO:0001649//osteoblast differentiation;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0006414//translational elongation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process",GO:0003735//structural constituent of ribosome;GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02958//Ribosome
6210,0,73,2,74,279,0,0,0,0,0,0,0,RPS15A;ribosomal protein S15a,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0022627//cytosolic small ribosomal subunit,"GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006414//translational elongation;GO:0016032//viral process;GO:0045787//positive regulation of cell cycle;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0008284//positive regulation of cell proliferation;GO:0010467//gene expression;GO:0009615//response to virus;GO:0006412//translation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K02957//Ribosome
6217,0,0,1,4,36,0,0,0,0,0,0,0,RPS16;ribosomal protein S16,GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0015935//small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0022627//cytosolic small ribosomal subunit,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0006364//rRNA processing;GO:0042274//ribosomal small subunit biogenesis",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003723//RNA binding,K02960//Ribosome
6218,0,44,0,47,92,0,0,0,0,0,0,0,RPS17;ribosomal protein S17,GO:0022627//cytosolic small ribosomal subunit;GO:0005840//ribosome;GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,"GO:0006412//translation;GO:0010467//gene expression;GO:0006364//rRNA processing;GO:0000028//ribosomal small subunit assembly;GO:0042274//ribosomal small subunit biogenesis;GO:0019058//viral life cycle;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0019083//viral transcription;GO:0034101//erythrocyte homeostasis;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006414//translational elongation",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02962//Ribosome
622,0,0,0,11,9,0,0,0,1,105,1,236,"BDH1;3-hydroxybutyrate dehydrogenase, type 1",GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus,GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0051412//response to corticosterone;GO:0032355//response to estradiol;GO:0042594//response to starvation;GO:0046686//response to cadmium ion;GO:0060416//response to growth hormone;GO:0060612//adipose tissue development;GO:0007420//brain development;GO:0045471//response to ethanol;GO:0042493//response to drug;GO:0046952//ketone body catabolic process;GO:0044255//cellular lipid metabolic process;GO:0046951//ketone body biosynthetic process;GO:0001889//liver development;GO:0009636//response to toxic substance;GO:0032868//response to insulin;GO:0044281//small molecule metabolic process,GO:0005543//phospholipid binding;GO:0003858//3-hydroxybutyrate dehydrogenase activity,K00019//Butanoate metabolism;Metabolic pathways;Synthesis and degradation of ketone bodies
6222,0,5,0,0,4,0,0,0,0,2,0,0,RPS18;ribosomal protein S18,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0015935//small ribosomal subunit;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005840//ribosome,"GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0042254//ribosome biogenesis;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation",GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019843//rRNA binding,K02964//Ribosome
6223,0,19,3,19,31,26,2,5,25,0,0,0,RPS19;ribosomal protein S19,GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005840//ribosome;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005737//cytoplasm,"GO:0042274//ribosomal small subunit biogenesis;GO:0000028//ribosomal small subunit assembly;GO:0006364//rRNA processing;GO:0030218//erythrocyte differentiation;GO:0009991//response to extracellular stimulus;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0051262//protein tetramerization;GO:0060265//positive regulation of respiratory burst involved in inflammatory response;GO:0006412//translation;GO:0010467//gene expression;GO:0060266//negative regulation of respiratory burst involved in inflammatory response;GO:0051272//positive regulation of cellular component movement;GO:0030490//maturation of SSU-rRNA;GO:0007000//nucleolus organization;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0002548//monocyte chemotaxis;GO:0044267//cellular protein metabolic process",GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome;GO:0017134//fibroblast growth factor binding,K02966//Ribosome
6224,30,327,12,322,1248,0,0,0,0,0,8,0,RPS20;ribosomal protein S20,GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,"GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016071//mRNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0016032//viral process;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02969//Ribosome
6227,73,17,0,1,9,0,0,114,4,0,0,0,RPS21;ribosomal protein S21,GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0015935//small ribosomal subunit,"GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412//translation;GO:0010467//gene expression;GO:0042274//ribosomal small subunit biogenesis;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0000461//endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0016032//viral process;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0016071//mRNA metabolic process",GO:0047485//protein N-terminus binding;GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,K02971//Ribosome
6228,85,85,7,203,520,0,39,0,9,0,12,0,RPS23;ribosomal protein S23,GO:0016020//membrane;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005730//nucleolus;GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm,"GO:0016032//viral process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02973//Ribosome
6229,85,49,0,61,232,11,29,1,70,0,0,0,RPS24;ribosomal protein S24,GO:0005730//nucleolus;GO:0015935//small ribosomal subunit;GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0022627//cytosolic small ribosomal subunit,"GO:0006412//translation;GO:0010467//gene expression;GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0019058//viral life cycle;GO:0019083//viral transcription;GO:0034101//erythrocyte homeostasis;GO:0006413//translational initiation;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0016032//viral process;GO:0006414//translational elongation;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003735//structural constituent of ribosome;GO:0031369//translation initiation factor binding,K02974//Ribosome
6230,0,50,1,98,195,0,0,0,19,0,0,0,RPS25;ribosomal protein S25,GO:0015935//small ribosomal subunit;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005840//ribosome;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,"GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0016032//viral process;GO:0000028//ribosomal small subunit assembly;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006415//translational termination;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02975//Ribosome
6231,0,23,0,8,351,55,35,38,0,0,0,0,RPS26;ribosomal protein S26,GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0015935//small ribosomal subunit;GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0033119//negative regulation of RNA splicing;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome;GO:0003729//mRNA binding,K02976//Ribosome
6232,0,0,0,1,1,0,0,0,0,0,0,0,RPS27;ribosomal protein S27,GO:0005840//ribosome;GO:0005829//cytosol;GO:0005634//nucleus;GO:0022627//cytosolic small ribosomal subunit,"GO:0010467//gene expression;GO:0000278//mitotic cell cycle;GO:0044267//cellular protein metabolic process;GO:0019083//viral transcription;GO:0006413//translational initiation;GO:0008283//cell proliferation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0016032//viral process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0003735//structural constituent of ribosome;GO:0003677//DNA binding,K02978//Ribosome
6233,0,110,4,149,350,0,1,56,3,0,6,0,RPS27A;ribosomal protein S27a,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0010008//endosome membrane;GO:0005654//nucleoplasm;GO:0015935//small ribosomal subunit;GO:0030666//endocytic vesicle membrane;GO:0005829//cytosol;GO:0022627//cytosolic small ribosomal subunit,"GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071456//cellular response to hypoxia;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006412//translation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0006281//DNA repair;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0061024//membrane organization;GO:0019221//cytokine-mediated signaling pathway;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006915//apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007254//JNK cascade;GO:0032481//positive regulation of type I interferon production;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045087//innate immune response;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0034146//toll-like receptor 5 signaling pathway;GO:0019082//viral protein processing;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006414//translational elongation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0075733//intracellular transport of virus;GO:0016197//endosomal transport;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0019083//viral transcription;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0019058//viral life cycle;GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0032480//negative regulation of type I interferon production;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0055085//transmembrane transport;GO:0007220//Notch receptor processing;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0016071//mRNA metabolic process;GO:0007219//Notch signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0044267//cellular protein metabolic process;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0019068//virion assembly;GO:0034220//ion transmembrane transport;GO:0006413//translational initiation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000209//protein polyubiquitination;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0034162//toll-like receptor 9 signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0050852//T cell receptor signaling pathway",GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0003735//structural constituent of ribosome,K02977//Ribosome
6234,0,49,1,7,28,0,13,0,0,0,12,0,RPS28;ribosomal protein S28,GO:0005737//cytoplasm;GO:0022627//cytosolic small ribosomal subunit;GO:0070062//extracellular vesicular exosome;GO:0015935//small ribosomal subunit;GO:0005829//cytosol,"GO:0006364//rRNA processing;GO:0016032//viral process;GO:0042274//ribosomal small subunit biogenesis;GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K02979//Ribosome
6235,0,7496,2044,21,7283,0,1,4,985,1,5,0,RPS29;ribosomal protein S29,GO:0022627//cytosolic small ribosomal subunit;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0015935//small ribosomal subunit;GO:0005925//focal adhesion,"GO:0016032//viral process;GO:0016070//RNA metabolic process;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression",GO:0003735//structural constituent of ribosome;GO:0008270//zinc ion binding,K02980//Ribosome;K02912//Ribosome
6236,0,0,0,0,0,0,0,0,17,0,0,0,RRAD;Ras-related associated with diabetes,GO:0005886//plasma membrane,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005516//calmodulin binding;GO:0005515//protein binding,-
6237,0,0,0,0,11,28,0,1,16,139,0,0,RRAS;related RAS viral (r-ras) oncogene homolog,GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0006184//GTP catabolic process;GO:0045766//positive regulation of angiogenesis;GO:0007265//Ras protein signal transduction;GO:0030336//negative regulation of cell migration;GO:0007268//synaptic transmission;GO:0007411//axon guidance,GO:0005515//protein binding;GO:0019003//GDP binding;GO:0032403//protein complex binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07829//Regulation of actin cytoskeleton;HTLV-I infection;Tight junction;MAPK signaling pathway
6238,190,18,1,0,16,13,25,91,26,2,16,1,RRBP1;ribosome binding protein 1,GO:0016020//membrane;GO:0005840//ribosome;GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0006412//translation;GO:0001649//osteoblast differentiation;GO:0015031//protein transport,GO:0044822//poly(A) RNA binding;GO:0004872//receptor activity,K14000//Protein processing in endoplasmic reticulum
6239,0,24,0,7,45,43,0,17,58,14,32,0,RREB1;ras responsive element binding protein 1,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0016604//nuclear body;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007265//Ras protein signal transduction;GO:0007275//multicellular organismal development",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
624,0,0,0,0,4,51,0,0,39,0,12,0,BDKRB2;bradykinin receptor B2,GO:0005887//integral component of plasma membrane;GO:0005768//endosome;GO:0005886//plasma membrane,GO:0006939//smooth muscle contraction;GO:0006954//inflammatory response;GO:0008015//blood circulation;GO:0050482//arachidonic acid secretion;GO:0007166//cell surface receptor signaling pathway;GO:0042311//vasodilation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019229//regulation of vasoconstriction;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:1902239//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator;GO:0043114//regulation of vascular permeability;GO:0008152//metabolic process;GO:0042310//vasoconstriction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009651//response to salt stress,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0046982//protein heterodimerization activity;GO:0004947//bradykinin receptor activity;GO:0005515//protein binding;GO:0031702//type 1 angiotensin receptor binding;GO:0002020//protease binding,K03916//Endocrine and other factor-regulated calcium reabsorption;Calcium signaling pathway;Complement and coagulation cascades;Neuroactive ligand-receptor interaction;Chagas disease (American trypanosomiasis);Regulation of actin cytoskeleton
6240,0,102,0,29,75,1,0,0,68,0,0,0,RRM1;ribonucleotide reductase M1,GO:0005654//nucleoplasm;GO:0005635//nuclear envelope;GO:0042995//cell projection;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0060041//retina development in camera-type eye;GO:0015949//nucleobase-containing small molecule interconversion;GO:0010212//response to ionizing radiation;GO:0044281//small molecule metabolic process;GO:0051290//protein heterotetramerization;GO:0055114//oxidation-reduction process;GO:0021846//cell proliferation in forebrain;GO:0006206//pyrimidine nucleobase metabolic process;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0008584//male gonad development;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle,"GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor;GO:0005524//ATP binding;GO:0005515//protein binding",K10807//Purine metabolism;Glutathione metabolism;Pyrimidine metabolism;Metabolic pathways
6241,0,0,0,0,0,0,0,0,4,0,0,0,RRM2;ribonucleotide reductase M2,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0009186//deoxyribonucleoside diphosphate metabolic process;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0009263//deoxyribonucleotide biosynthetic process;GO:0055114//oxidation-reduction process;GO:0051290//protein heterotetramerization;GO:0044281//small molecule metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0000082//G1/S transition of mitotic cell cycle,"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004748//ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor",K10808//Metabolic pathways;p53 signaling pathway;Glutathione metabolism;Pyrimidine metabolism;Purine metabolism
6242,0,0,0,0,0,18,19,0,25,0,0,0,RTKN;rhotekin,-,GO:0006915//apoptotic process;GO:0043086//negative regulation of catalytic activity;GO:0007266//Rho protein signal transduction;GO:0007165//signal transduction,GO:0005525//GTP binding;GO:0005515//protein binding;GO:0017049//GTP-Rho binding;GO:0005095//GTPase inhibitor activity,-
6247,41,0,0,20,0,0,0,0,17,0,0,0,RS1;retinoschisin 1,GO:0019897//extrinsic component of plasma membrane;GO:0005615//extracellular space,GO:0016062//adaptation of rhodopsin mediated signaling;GO:0007155//cell adhesion;GO:0007275//multicellular organismal development;GO:0007601//visual perception;GO:0010842//retina layer formation,"GO:0001786//phosphatidylserine binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",K03902//Complement and coagulation cascades
6248,0,0,0,20,28,0,0,35,0,0,0,0,"RSC1A1;regulatory solute carrier protein, family 1, member 1",GO:0005903//brush border;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005794//Golgi apparatus,"GO:0050892//intestinal absorption;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051051//negative regulation of transport;GO:0006810//transport",GO:0008200//ion channel inhibitor activity,-
6249,0,2,0,8,81,10,0,0,23,0,36,0,CLIP1;CAP-GLY domain containing linker protein 1,GO:0005829//cytosol;GO:0035371//microtubule plus-end;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0030659//cytoplasmic vesicle membrane;GO:0001726//ruffle;GO:0000776//kinetochore;GO:0005882//intermediate filament;GO:0005768//endosome;GO:0044354//macropinosome;GO:0005813//centrosome,GO:0006810//transport;GO:0001578//microtubule bundle formation;GO:0031116//positive regulation of microtubule polymerization;GO:0000278//mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0008017//microtubule binding;GO:0051010//microtubule plus-end binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0015631//tubulin binding;GO:0003676//nucleic acid binding,-
6251,0,0,0,12,51,0,0,0,0,0,0,0,RSU1;Ras suppressor protein 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0034329//cell junction assembly;GO:0007265//Ras protein signal transduction;GO:2000179//positive regulation of neural precursor cell proliferation,-,K12796//NOD-like receptor signaling pathway
6252,0,0,0,0,13,14,0,76,82,0,6,0,RTN1;reticulon 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030182//neuron differentiation,GO:0005515//protein binding,K00688//Starch and sucrose metabolism;Insulin signaling pathway
6253,0,0,0,0,0,0,19,0,21,0,0,0,RTN2;reticulon 2,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0014802//terminal cisterna;GO:0005783//endoplasmic reticulum;GO:0030315//T-tubule,GO:0065002//intracellular protein transmembrane transport;GO:0008219//cell death;GO:0046324//regulation of glucose import,GO:0005515//protein binding,K00688//Starch and sucrose metabolism;Insulin signaling pathway
6256,145,27,0,18,37,18,57,1,57,0,27,0,"RXRA;retinoid X receptor, alpha",GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm,GO:0006766//vitamin metabolic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0032526//response to retinoic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035357//peroxisome proliferator activated receptor signaling pathway;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0019048//modulation by virus of host morphology or physiology;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008203//cholesterol metabolic process;GO:0010467//gene expression;GO:0001893//maternal placenta development;GO:0007566//embryo implantation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0051289//protein homotetramerization;GO:0001701//in utero embryonic development;GO:0048384//retinoic acid receptor signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0043010//camera-type eye development;GO:0044281//small molecule metabolic process,GO:0003707//steroid hormone receptor activity;GO:0003708//retinoic acid receptor activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042809//vitamin D receptor binding;GO:0044212//transcription regulatory region DNA binding;GO:0044323//retinoic acid-responsive element binding;GO:0070644//vitamin D response element binding;GO:0031490//chromatin DNA binding;GO:0003713//transcription coactivator activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005515//protein binding;GO:0004886//9-cis retinoic acid receptor activity;GO:0003677//DNA binding;GO:0019899//enzyme binding,K08524//Transcriptional misregulation in cancer;Small cell lung cancer;Pathways in cancer;PPAR signaling pathway;Bile secretion;Thyroid cancer;Adipocytokine signaling pathway;Non-small cell lung cancer;Hepatitis C
6257,0,0,0,0,1,0,0,0,0,0,0,0,"RXRB;retinoid X receptor, beta",GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0060038//cardiac muscle cell proliferation;GO:0001701//in utero embryonic development;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048384//retinoic acid receptor signaling pathway;GO:0071300//cellular response to retinoic acid;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0001893//maternal placenta development;GO:0010467//gene expression,GO:0004886//9-cis retinoic acid receptor activity;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding,K08525//Non-small cell lung cancer;Adipocytokine signaling pathway;Pathways in cancer;PPAR signaling pathway;Transcriptional misregulation in cancer;Thyroid cancer;Small cell lung cancer
6258,0,0,0,0,0,7,0,7,10,0,9,0,"RXRG;retinoid X receptor, gamma",GO:0005654//nucleoplasm,GO:0030182//neuron differentiation;GO:0007519//skeletal muscle tissue development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007422//peripheral nervous system development;GO:0043401//steroid hormone mediated signaling pathway;GO:0031641//regulation of myelination;GO:0010467//gene expression;GO:0032526//response to retinoic acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048384//retinoic acid receptor signaling pathway;GO:0007507//heart development,GO:0004886//9-cis retinoic acid receptor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding,K08526//Thyroid cancer;Small cell lung cancer;Transcriptional misregulation in cancer;Pathways in cancer;Adipocytokine signaling pathway;PPAR signaling pathway;Non-small cell lung cancer
6259,0,0,0,14,20,0,0,0,60,0,9,0,RYK;receptor-like tyrosine kinase,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane,GO:0031175//neuron projection development;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction;GO:0043410//positive regulation of MAPK cascade;GO:0022038//corpus callosum development;GO:0007411//axon guidance;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030182//neuron differentiation,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding,-
6261,157,0,0,0,0,45,69,166,109,221,25,1,RYR1;ryanodine receptor 1 (skeletal),GO:0030314//junctional membrane complex;GO:0016529//sarcoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0031674//I band;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0005790//smooth endoplasmic reticulum;GO:0014802//terminal cisterna;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005938//cell cortex;GO:0005737//cytoplasm,GO:0006816//calcium ion transport;GO:0006936//muscle contraction;GO:0055085//transmembrane transport;GO:0051480//cytosolic calcium ion homeostasis;GO:0070588//calcium ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0001666//response to hypoxia;GO:0071313//cellular response to caffeine;GO:0043588//skin development;GO:0051209//release of sequestered calcium ion into cytosol;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0048741//skeletal muscle fiber development;GO:0031000//response to caffeine;GO:0043931//ossification involved in bone maturation;GO:0003151//outflow tract morphogenesis,GO:0005516//calmodulin binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0002020//protease binding;GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0005262//calcium channel activity;GO:0005509//calcium ion binding;GO:0015278//calcium-release channel activity,K04961//Long-term depression;Calcium signaling pathway
6262,203,0,0,0,2,70,90,0,175,168,17,11,RYR2;ryanodine receptor 2 (cardiac),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0043234//protein complex;GO:0030018//Z disc;GO:0016529//sarcoplasmic reticulum;GO:0034704//calcium channel complex;GO:0005790//smooth endoplasmic reticulum;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane,GO:0035584//calcium-mediated signaling using intracellular calcium source;GO:0006874//cellular calcium ion homeostasis;GO:1901896//positive regulation of calcium-transporting ATPase activity;GO:0051284//positive regulation of sequestering of calcium ion;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055085//transmembrane transport;GO:0060070//canonical Wnt signaling pathway;GO:0003143//embryonic heart tube morphogenesis;GO:0005513//detection of calcium ion;GO:0031000//response to caffeine;GO:0019722//calcium-mediated signaling;GO:0002027//regulation of heart rate;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0003300//cardiac muscle hypertrophy;GO:0001666//response to hypoxia;GO:0034220//ion transmembrane transport;GO:0086029//Purkinje myocyte to ventricular cardiac muscle cell signaling;GO:0086005//ventricular cardiac muscle cell action potential;GO:0055117//regulation of cardiac muscle contraction;GO:0010460//positive regulation of heart rate;GO:0060048//cardiac muscle contraction;GO:0086094//positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction;GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0030509//BMP signaling pathway;GO:0006816//calcium ion transport;GO:0097050//type B pancreatic cell apoptotic process;GO:0051775//response to redox state;GO:0051480//cytosolic calcium ion homeostasis;GO:0071313//cellular response to caffeine;GO:0051209//release of sequestered calcium ion into cytosol;GO:0071872//cellular response to epinephrine stimulus;GO:0014808//release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0003220//left ventricular cardiac muscle tissue morphogenesis;GO:0060402//calcium ion transport into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0072599//establishment of protein localization to endoplasmic reticulum,GO:0043924//suramin binding;GO:0019899//enzyme binding;GO:0005516//calmodulin binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0042802//identical protein binding;GO:0005218//intracellular ligand-gated calcium channel activity;GO:0048763//calcium-induced calcium release activity;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0005262//calcium channel activity;GO:0043621//protein self-association;GO:0005509//calcium ion binding;GO:0015278//calcium-release channel activity,K04962//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Cardiac muscle contraction;Calcium signaling pathway;Dilated cardiomyopathy;Pancreatic secretion
6263,65,0,0,0,12,77,44,94,211,202,42,0,RYR3;ryanodine receptor 3,GO:0033017//sarcoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0030314//junctional membrane complex,GO:0051289//protein homotetramerization;GO:0006941//striated muscle contraction;GO:0071277//cellular response to calcium ion;GO:0071318//cellular response to ATP;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0071286//cellular response to magnesium ion;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0034220//ion transmembrane transport;GO:0071313//cellular response to caffeine,GO:0048763//calcium-induced calcium release activity;GO:0005516//calmodulin binding;GO:0005219//ryanodine-sensitive calcium-release channel activity;GO:0015278//calcium-release channel activity;GO:0005509//calcium ion binding,K04963//Calcium signaling pathway;Salivary secretion;Alzheimer's disease
627,0,1,0,61,55,12,20,4,131,276,3,101,BDNF;brain-derived neurotrophic factor,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0005576//extracellular region,"GO:0072347//response to anesthetic;GO:0007399//nervous system development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0014076//response to fluoxetine;GO:0001666//response to hypoxia;GO:0001657//ureteric bud development;GO:0046668//regulation of retinal cell programmed cell death;GO:0009725//response to hormone;GO:0051965//positive regulation of synapse assembly;GO:0001662//behavioral fear response;GO:0097484//dendrite extension;GO:0061193//taste bud development;GO:0045843//negative regulation of striated muscle tissue development;GO:0007411//axon guidance;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0014047//glutamate secretion;GO:0008038//neuron recognition;GO:0048675//axon extension;GO:0055093//response to hyperoxia;GO:0007611//learning or memory;GO:0007406//negative regulation of neuroblast proliferation;GO:0006120//mitochondrial electron transport, NADH to ubiquinone;GO:0007412//axon target recognition;GO:0007623//circadian rhythm;GO:0021675//nerve development;GO:0007631//feeding behavior;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0033189//response to vitamin A;GO:0016358//dendrite development;GO:0048839//inner ear development;GO:0045666//positive regulation of neuron differentiation;GO:0042490//mechanoreceptor differentiation;GO:0043524//negative regulation of neuron apoptotic process;GO:0002544//chronic inflammatory response;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0048170//positive regulation of long-term neuronal synaptic plasticity",GO:0008083//growth factor activity;GO:0005169//neurotrophin TRKB receptor binding,K04355//Neurotrophin signaling pathway;Huntington's disease;MAPK signaling pathway;Cocaine addiction;Alcoholism
6271,40,0,0,19,15,0,0,26,0,0,38,0,S100A1;S100 calcium binding protein A1,GO:0030018//Z disc;GO:0043234//protein complex;GO:0005634//nucleus;GO:0031430//M band;GO:0043005//neuron projection;GO:0016529//sarcoplasmic reticulum,GO:0008016//regulation of heart contraction;GO:0021762//substantia nigra development;GO:1901387//positive regulation of voltage-gated calcium channel activity;GO:0035556//intracellular signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0044548//S100 protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0051117//ATPase binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding,-
6272,0,0,0,8,6,0,32,0,79,0,0,0,SORT1;sortilin 1,GO:0032580//Golgi cisterna membrane;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030140//trans-Golgi network transport vesicle;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005905//coated pit;GO:0031965//nuclear membrane;GO:0005765//lysosomal membrane,GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0032868//response to insulin;GO:0038180//nerve growth factor signaling pathway;GO:0001503//ossification;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051005//negative regulation of lipoprotein lipase activity;GO:0016050//vesicle organization;GO:0046323//glucose import;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0032509//endosome transport via multivesicular body sorting pathway;GO:0014902//myotube differentiation;GO:0006895//Golgi to endosome transport;GO:0007275//multicellular organismal development;GO:0010468//regulation of gene expression;GO:0006897//endocytosis;GO:0008333//endosome to lysosome transport;GO:0048227//plasma membrane to endosome transport,"GO:0030379//neurotensin receptor activity, non-G-protein coupled;GO:0010465//nerve growth factor receptor activity;GO:0019899//enzyme binding;GO:0048406//nerve growth factor binding;GO:0005515//protein binding",K12388//Neurotrophin signaling pathway;Lysosome
6274,0,0,0,0,0,0,0,0,36,0,0,0,S100A3;S100 calcium binding protein A3,GO:0005737//cytoplasm;GO:0005730//nucleolus,-,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding,-
6275,0,0,0,0,0,13,0,0,22,0,0,0,S100A4;S100 calcium binding protein A4,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome,GO:0001837//epithelial to mesenchymal transition;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0050786//RAGE receptor binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003779//actin binding,K14734//Mineral absorption
6277,0,0,0,0,0,0,0,0,3,0,0,0,S100A6;S100 calcium binding protein A6,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0001726//ruffle;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane,GO:0007409//axonogenesis;GO:0048146//positive regulation of fibroblast proliferation;GO:0007165//signal transduction;GO:0034220//ion transmembrane transport,GO:0044548//S100 protein binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0008270//zinc ion binding;GO:0005523//tropomyosin binding;GO:0015075//ion transmembrane transporter activity,-
6278,0,0,0,0,0,0,0,0,0,0,13,0,S100A7;S100 calcium binding protein A7,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005925//focal adhesion;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,GO:0090026//positive regulation of monocyte chemotaxis;GO:0010820//positive regulation of T cell chemotaxis;GO:0032496//response to lipopolysaccharide;GO:0008544//epidermis development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030216//keratinocyte differentiation;GO:0001525//angiogenesis;GO:0051238//sequestering of metal ion;GO:0050829//defense response to Gram-negative bacterium;GO:0000302//response to reactive oxygen species;GO:0071624//positive regulation of granulocyte chemotaxis;GO:0045087//innate immune response,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0050786//RAGE receptor binding,-
6279,0,0,0,0,0,0,0,0,11,0,0,0,S100A8;S100 calcium binding protein A8,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0010043//response to zinc ion;GO:0006954//inflammatory response;GO:0002526//acute inflammatory response;GO:0002523//leukocyte migration involved in inflammatory response;GO:0070488//neutrophil aggregation;GO:0050729//positive regulation of inflammatory response;GO:0032119//sequestering of zinc ion;GO:0006914//autophagy;GO:0001816//cytokine production;GO:0045087//innate immune response;GO:0051493//regulation of cytoskeleton organization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0030307//positive regulation of cell growth;GO:0030593//neutrophil chemotaxis;GO:0032602//chemokine production;GO:0050832//defense response to fungus;GO:0042060//wound healing;GO:0002544//chronic inflammatory response;GO:0042742//defense response to bacterium;GO:0045471//response to ethanol,GO:0050544//arachidonic acid binding;GO:0008270//zinc ion binding;GO:0050786//RAGE receptor binding;GO:0005509//calcium ion binding;GO:0035662//Toll-like receptor 4 binding;GO:0008017//microtubule binding;GO:0005515//protein binding,K14734//Mineral absorption
6280,0,1,0,0,0,0,0,0,0,0,0,0,S100A9;S100 calcium binding protein A9,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0045471//response to ethanol;GO:0002544//chronic inflammatory response;GO:0042742//defense response to bacterium;GO:0030593//neutrophil chemotaxis;GO:0032496//response to lipopolysaccharide;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0030307//positive regulation of cell growth;GO:0050832//defense response to fungus;GO:0032602//chemokine production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051493//regulation of cytoskeleton organization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045087//innate immune response;GO:0007267//cell-cell signaling;GO:0001816//cytokine production;GO:0032119//sequestering of zinc ion;GO:0050729//positive regulation of inflammatory response;GO:0070488//neutrophil aggregation;GO:0006914//autophagy;GO:0002523//leukocyte migration involved in inflammatory response;GO:0007165//signal transduction;GO:0010043//response to zinc ion;GO:0006954//inflammatory response,GO:0005509//calcium ion binding;GO:0050786//RAGE receptor binding;GO:0008270//zinc ion binding;GO:0050544//arachidonic acid binding;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0016209//antioxidant activity;GO:0008017//microtubule binding;GO:0035662//Toll-like receptor 4 binding,-
6281,0,18,1,27,97,0,0,0,7,0,0,0,S100A10;S100 calcium binding protein A10,GO:0070062//extracellular vesicular exosome;GO:0045121//membrane raft;GO:0019897//extrinsic component of plasma membrane,GO:0051894//positive regulation of focal adhesion assembly;GO:0051290//protein heterotetramerization;GO:0051099//positive regulation of binding;GO:0032855//positive regulation of Rac GTPase activity;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0006900//membrane budding;GO:0071229//cellular response to acid chemical;GO:0090002//establishment of protein localization to plasma membrane;GO:0051496//positive regulation of stress fiber assembly;GO:0001765//membrane raft assembly,GO:0008289//lipid binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0044325//ion channel binding;GO:0005515//protein binding,-
6282,0,28,0,4,44,21,0,0,0,0,0,0,S100A11;S100 calcium binding protein A11,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0001726//ruffle;GO:0070062//extracellular vesicular exosome,GO:0008156//negative regulation of DNA replication;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction,GO:0044548//S100 protein binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
6283,0,0,0,0,0,0,0,0,9,0,0,0,S100A12;S100 calcium binding protein A12,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0030593//neutrophil chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0045576//mast cell activation;GO:0050832//defense response to fungus;GO:0050663//cytokine secretion;GO:0002548//monocyte chemotaxis;GO:0042742//defense response to bacterium;GO:0045087//innate immune response;GO:0006954//inflammatory response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031640//killing of cells of other organism;GO:0043406//positive regulation of MAP kinase activity;GO:0006805//xenobiotic metabolic process,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0050786//RAGE receptor binding;GO:0005515//protein binding;GO:0005507//copper ion binding,-
6284,0,0,0,0,39,12,10,0,13,0,0,0,S100A13;S100 calcium binding protein A13,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0042629//mast cell granule;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0008284//positive regulation of cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0046688//response to copper ion;GO:0051602//response to electrical stimulus;GO:0043303//mast cell degranulation;GO:0050663//cytokine secretion;GO:0050703//interleukin-1 alpha secretion;GO:0008360//regulation of cell shape,GO:0008289//lipid binding;GO:0005507//copper ion binding;GO:0017134//fibroblast growth factor binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0050786//RAGE receptor binding,K14734//Mineral absorption
6285,0,0,0,0,0,12,0,0,18,0,0,0,S100B;S100 calcium binding protein B,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0005576//extracellular region,GO:0008360//regulation of cell shape;GO:0007417//central nervous system development;GO:0048708//astrocyte differentiation;GO:0008283//cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051384//response to glucocorticoid;GO:0007409//axonogenesis;GO:0071456//cellular response to hypoxia;GO:0007611//learning or memory;GO:0008284//positive regulation of cell proliferation;GO:0045087//innate immune response;GO:0048168//regulation of neuronal synaptic plasticity;GO:0043065//positive regulation of apoptotic process;GO:0060291//long-term synaptic potentiation;GO:0051597//response to methylmercury;GO:0007613//memory;GO:2001015//negative regulation of skeletal muscle cell differentiation,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0050786//RAGE receptor binding;GO:0048306//calcium-dependent protein binding;GO:0008270//zinc ion binding;GO:0048156//tau protein binding;GO:0042802//identical protein binding;GO:0044548//S100 protein binding,-
6289,0,0,0,0,0,0,1,0,14,0,0,0,SAA2;serum amyloid A2,GO:0034364//high-density lipoprotein particle;GO:0070062//extracellular vesicular exosome,GO:0006953//acute-phase response,-,-
629,1,0,0,0,0,0,0,0,12,0,0,0,CFB;complement factor B,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0006956//complement activation;GO:0045087//innate immune response;GO:0006508//proteolysis;GO:0030449//regulation of complement activation;GO:0006957//complement activation, alternative pathway",GO:0001848//complement binding;GO:0004252//serine-type endopeptidase activity,K01335//Staphylococcus aureus infection;Complement and coagulation cascades
6293,7,0,0,0,0,0,0,0,0,0,0,0,VPS52;vacuolar protein sorting 52 homolog (S. cerevisiae),GO:0010008//endosome membrane;GO:0005794//Golgi apparatus,GO:0010668//ectodermal cell differentiation;GO:0015031//protein transport;GO:0048611//embryonic ectodermal digestive tract development,GO:0005515//protein binding,-
6294,1,0,1,2,28,0,2,1,27,0,16,0,SAFB;scaffold attachment factor B,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0042445//hormone metabolic process;GO:0040007//growth;GO:0006325//chromatin organization",GO:0001047//core promoter binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
6295,0,0,0,0,0,13,0,0,47,0,2,359,SAG;S-antigen; retina and pineal gland (arrestin),GO:0001917//photoreceptor inner segment;GO:0001750//photoreceptor outer segment;GO:0005829//cytosol,"GO:0007601//visual perception;GO:0043086//negative regulation of catalytic activity;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0007603//phototransduction, visible light",GO:0004864//protein phosphatase inhibitor activity;GO:0002046//opsin binding;GO:0051219//phosphoprotein binding,K04439//Olfactory transduction;Morphine addiction;Phototransduction;Endocytosis;Chemokine signaling pathway;MAPK signaling pathway;Dopaminergic synapse
6296,0,32,40,17,43,13,22,0,25,0,0,0,ACSM3;acyl-CoA synthetase medium-chain family member 3,GO:0005759//mitochondrial matrix,GO:0042632//cholesterol homeostasis;GO:0006633//fatty acid biosynthetic process;GO:0008217//regulation of blood pressure,GO:0015645//fatty acid ligase activity;GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,K01896//Metabolic pathways;Lipoic acid metabolism;Butanoate metabolism
6297,0,1,0,0,7,0,60,0,50,0,1,318,SALL2;spalt-like transcription factor 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
6299,0,0,0,0,0,14,4,0,34,148,0,0,SALL1;spalt-like transcription factor 1,GO:0016581//NuRD complex;GO:0000792//heterochromatin;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0010369//chromocenter,"GO:0001822//kidney development;GO:0007507//heart development;GO:0021983//pituitary gland development;GO:2000177//regulation of neural precursor cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060173//limb development;GO:0045879//negative regulation of smoothened signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031129//inductive cell-cell signaling;GO:0030325//adrenal gland development;GO:0021889//olfactory bulb interneuron differentiation;GO:0042733//embryonic digit morphogenesis;GO:0042473//outer ear morphogenesis;GO:0006351//transcription, DNA-templated;GO:0001657//ureteric bud development;GO:0001843//neural tube closure;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0061034//olfactory bulb mitral cell layer development;GO:0045666//positive regulation of neuron differentiation;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0021553//olfactory nerve development;GO:0003281//ventricular septum development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030177//positive regulation of Wnt signaling pathway;GO:0048566//embryonic digestive tract development;GO:0072092//ureteric bud invasion;GO:0035137//hindlimb morphogenesis;GO:0008406//gonad development;GO:0035136//forelimb morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016575//histone deacetylation",GO:0004407//histone deacetylase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0008013//beta-catenin binding,-
6300,0,0,0,0,1,0,13,0,44,0,0,0,MAPK12;mitogen-activated protein kinase 12,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol,"GO:0007265//Ras protein signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0045445//myoblast differentiation;GO:0007050//cell cycle arrest;GO:0042692//muscle cell differentiation;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0051149//positive regulation of muscle cell differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007517//muscle organ development;GO:0006975//DNA damage induced protein phosphorylation;GO:0000165//MAPK cascade;GO:0006351//transcription, DNA-templated",GO:0004674//protein serine/threonine kinase activity;GO:0004707//MAP kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K04441//RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Epithelial cell signaling in Helicobacter pylori infection;Oocyte meiosis;Amyotrophic lateral sclerosis (ALS);MAPK signaling pathway;T cell receptor signaling pathway;Toll-like receptor signaling pathway;Progesterone-mediated oocyte maturation;Influenza A;Pertussis;Tuberculosis;Salmonella infection;MAPK signaling pathway - yeast;Dopaminergic synapse;GnRH signaling pathway;VEGF signaling pathway;Neurotrophin signaling pathway;Hepatitis C;Toxoplasmosis;Osteoclast differentiation;Leishmaniasis;Shigellosis;Leukocyte transendothelial migration;NOD-like receptor signaling pathway;Retrograde endocannabinoid signaling;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis)
6301,0,1,3,20,107,1,23,3,0,144,1,446,SARS;seryl-tRNA synthetase,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0097056//selenocysteinyl-tRNA(Sec) biosynthetic process;GO:0010467//gene expression;GO:0006434//seryl-tRNA aminoacylation;GO:0008033//tRNA processing;GO:0006418//tRNA aminoacylation for protein translation;GO:0006412//translation,GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0004828//serine-tRNA ligase activity,K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
6302,0,0,0,12,44,0,0,0,19,0,24,0,TSPAN31;tetraspanin 31,GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0008284//positive regulation of cell proliferation,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
63027,113,0,0,21,18,54,134,0,36,0,39,1,"SLC22A23;solute carrier family 22, member 23",GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,-
6303,0,47,0,0,57,0,0,0,9,0,0,0,SAT1;spermidine/spermine N1-acetyltransferase 1,GO:0005829//cytosol;GO:0005622//intracellular,GO:0006596//polyamine biosynthetic process;GO:0009447//putrescine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0032918//spermidine acetylation;GO:0042127//regulation of cell proliferation;GO:0006595//polyamine metabolic process;GO:0044281//small molecule metabolic process;GO:0001525//angiogenesis,GO:0004145//diamine N-acetyltransferase activity;GO:0005515//protein binding;GO:0019809//spermidine binding,K00657//Metabolic pathways;ABC transporters;Arginine and proline metabolism
63035,78,0,0,1,14,10,0,0,26,88,0,0,BCORL1;BCL6 corepressor-like 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification",-,-
63036,0,0,0,0,0,0,0,0,18,0,0,0,"CELA2A;chymotrypsin-like elastase family, member 2A",GO:0036457//keratohyalin granule;GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0017171//serine hydrolase activity;GO:0004252//serine-type endopeptidase activity,K01346//Pancreatic secretion;Protein digestion and absorption
6304,0,36,0,36,205,14,0,0,75,0,3,0,SATB1;SATB homeobox 1,GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0005720//nuclear heterochromatin;GO:0016605//PML body,"GO:0016032//viral process;GO:0016571//histone methylation;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0008544//epidermis development;GO:0006915//apoptotic process;GO:0050798//activated T cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0060004//reflex",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0003690//double-stranded DNA binding,-
6305,30,1,2,36,45,25,0,68,60,1,4,0,SBF1;SET binding factor 1,GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0032851//positive regulation of Rab GTPase activity;GO:0007283//spermatogenesis;GO:0006470//protein dephosphorylation;GO:0008219//cell death,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0017112//Rab guanyl-nucleotide exchange factor activity,-
6307,0,0,0,6,18,13,33,0,8,0,0,0,MSMO1;methylsterol monooxygenase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,GO:0006631//fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0006633//fatty acid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process;GO:0008202//steroid metabolic process,GO:0005506//iron ion binding;GO:0000254//C-4 methylsterol oxidase activity,K07750//Steroid biosynthesis;Metabolic pathways
6309,0,0,0,23,75,33,13,31,24,52,11,0,SC5D;sterol-C5-desaturase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process;GO:0006629//lipid metabolic process;GO:0033490//cholesterol biosynthetic process via lathosterol,GO:0050046//lathosterol oxidase activity;GO:0000248//C-5 sterol desaturase activity;GO:0005506//iron ion binding,K00227//Metabolic pathways;Steroid biosynthesis;Biosynthesis of secondary metabolites
631,115,40,0,3,18,1,0,0,29,0,17,0,"BFSP1;beaded filament structural protein 1, filensin",GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0015629//actin cytoskeleton,GO:0070307//lens fiber cell development;GO:0048469//cell maturation,GO:0005200//structural constituent of cytoskeleton;GO:0005212//structural constituent of eye lens,-
6310,0,43,44,288,218,0,70,0,71,0,116,0,ATXN1;ataxin 1,GO:0043231//intracellular membrane-bounded organelle;GO:0042272//nuclear RNA export factor complex;GO:0042405//nuclear inclusion body;GO:0005730//nucleolus;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0008344//adult locomotory behavior;GO:0008219//cell death;GO:0006396//RNA processing;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008542//visual learning;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0042326//negative regulation of phosphorylation;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051168//nuclear export;GO:0006351//transcription, DNA-templated",GO:0008022//protein C-terminus binding;GO:0008266//poly(U) RNA binding;GO:0003677//DNA binding;GO:0043621//protein self-association;GO:0034046//poly(G) binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
6311,13,0,1,11,53,14,6,0,50,0,22,0,ATXN2;ataxin 2,GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005844//polysome;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus,GO:0016070//RNA metabolic process;GO:0048812//neuron projection morphogenesis;GO:0002091//negative regulation of receptor internalization;GO:0008219//cell death;GO:0050658//RNA transport;GO:0040015//negative regulation of multicellular organism growth;GO:0006417//regulation of translation;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0034063//stress granule assembly;GO:0048872//homeostasis of number of cells;GO:0021702//cerebellar Purkinje cell differentiation;GO:0050905//neuromuscular process,GO:0005154//epidermal growth factor receptor binding;GO:0003723//RNA binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
6314,0,23,0,1,17,25,64,0,21,0,1,285,ATXN7;ataxin 7,GO:0005730//nucleolus;GO:0015630//microtubule cytoskeleton;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006997//nucleus organization;GO:0006325//chromatin organization;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0016578//histone deubiquitination;GO:0000226//microtubule cytoskeleton organization;GO:0042326//negative regulation of phosphorylation;GO:0006351//transcription, DNA-templated;GO:0007601//visual perception;GO:0008219//cell death;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003682//chromatin binding,-
6315,78,27,0,9,0,0,0,1,0,0,0,0,ATXN8OS;ATXN8 opposite strand (non-protein coding),-,-,-,-
6317,0,0,0,0,0,0,14,0,0,1,0,0,"SERPINB3;serpin peptidase inhibitor, clade B (ovalbumin), member 3",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005634//nucleus,GO:0010951//negative regulation of endopeptidase activity;GO:0043086//negative regulation of catalytic activity;GO:0045861//negative regulation of proteolysis;GO:0030162//regulation of proteolysis;GO:0010466//negative regulation of peptidase activity;GO:0009615//response to virus,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0001618//virus receptor activity,K13963//Amoebiasis
6319,0,2,7,22,140,27,0,0,20,0,0,0,SCD;stearoyl-CoA desaturase (delta-9-desaturase),GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process,GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0005506//iron ion binding,K00507//Biosynthesis of unsaturated fatty acids;PPAR signaling pathway
6320,0,0,0,0,0,0,0,0,11,76,0,0,"CLEC11A;C-type lectin domain family 11, member A",GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0008284//positive regulation of cell proliferation,GO:0008083//growth factor activity;GO:0030246//carbohydrate binding,K10066//Phagosome;K12589//RNA degradation
6322,0,0,0,0,0,33,0,0,0,0,0,0,SCML1;sex comb on midleg-like 1 (Drosophila),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6323,53,0,0,0,0,20,58,145,95,0,17,0,"SCN1A;sodium channel, voltage-gated, type I, alpha subunit",GO:0001518//voltage-gated sodium channel complex;GO:0043194//axon initial segment;GO:0030018//Z disc;GO:0043025//neuronal cell body;GO:0033268//node of Ranvier;GO:0030315//T-tubule;GO:0014704//intercalated disc;GO:0005886//plasma membrane,GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0050884//neuromuscular process controlling posture;GO:0035725//sodium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0019227//neuronal action potential propagation;GO:0007628//adult walking behavior;GO:0019228//neuronal action potential,GO:0005248//voltage-gated sodium channel activity,K04833//Dopaminergic synapse
6324,145,0,0,0,0,0,0,0,0,0,0,1,"SCN1B;sodium channel, voltage-gated, type I, beta subunit",GO:0033268//node of Ranvier;GO:0001518//voltage-gated sodium channel complex;GO:0014704//intercalated disc;GO:0005576//extracellular region;GO:0030315//T-tubule,GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0051899//membrane depolarization;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0040011//locomotion;GO:0010976//positive regulation of neuron projection development;GO:0021966//corticospinal neuron axon guidance;GO:0007155//cell adhesion;GO:0019227//neuronal action potential propagation;GO:0061337//cardiac conduction;GO:0007268//synaptic transmission;GO:0060048//cardiac muscle contraction;GO:0010765//positive regulation of sodium ion transport;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0046684//response to pyrethroid;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086047//membrane depolarization during Purkinje myocyte cell action potential;GO:0035725//sodium ion transmembrane transport;GO:0007411//axon guidance,GO:0086062//voltage-gated sodium channel activity involved in Purkinje myocyte action potential;GO:0019871//sodium channel inhibitor activity;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0017080//sodium channel regulator activity;GO:0005248//voltage-gated sodium channel activity,-
6326,9,0,0,0,0,7,0,0,52,0,0,0,"SCN2A;sodium channel, voltage-gated, type II, alpha subunit",GO:0001518//voltage-gated sodium channel complex;GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0034706//sodium channel complex;GO:0031226//intrinsic component of plasma membrane;GO:0033268//node of Ranvier;GO:0033270//paranode region of axon;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0014704//intercalated disc,GO:0042552//myelination;GO:0051402//neuron apoptotic process;GO:0008627//intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0019228//neuronal action potential;GO:0035725//sodium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0006814//sodium ion transport;GO:0086010//membrane depolarization during action potential,GO:0005248//voltage-gated sodium channel activity,-
6327,106,0,0,0,0,27,14,57,18,0,2,0,"SCN2B;sodium channel, voltage-gated, type II, beta subunit",GO:0001518//voltage-gated sodium channel complex,GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0046684//response to pyrethroid;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0007399//nervous system development;GO:0035725//sodium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060048//cardiac muscle contraction;GO:0086002//cardiac muscle cell action potential involved in contraction,GO:0017080//sodium channel regulator activity;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential,-
6328,0,0,0,0,1,5,27,0,39,0,22,0,"SCN3A;sodium channel, voltage-gated, type III, alpha subunit",GO:0005886//plasma membrane;GO:0001518//voltage-gated sodium channel complex;GO:0005737//cytoplasm,GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport,GO:0005248//voltage-gated sodium channel activity,-
6329,63,20,1,0,0,50,57,0,34,0,9,0,"SCN4A;sodium channel, voltage-gated, type IV, alpha subunit",GO:0005886//plasma membrane;GO:0001518//voltage-gated sodium channel complex;GO:0005887//integral component of plasma membrane,GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0019228//neuronal action potential;GO:0006936//muscle contraction;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport,GO:0005248//voltage-gated sodium channel activity,-
633,0,0,0,0,0,16,1,0,0,0,0,0,BGN;biglycan,GO:0031012//extracellular matrix;GO:0042383//sarcolemma;GO:0005796//Golgi lumen;GO:0043202//lysosomal lumen;GO:0030133//transport vesicle;GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0009986//cell surface,GO:0030204//chondroitin sulfate metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0030198//extracellular matrix organization;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0001974//blood vessel remodeling;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process,GO:0005201//extracellular matrix structural constituent;GO:0050840//extracellular matrix binding;GO:0005539//glycosaminoglycan binding,-
6331,163,0,0,0,0,26,26,130,53,0,6,0,"SCN5A;sodium channel, voltage-gated, type V, alpha subunit",GO:0016328//lateral plasma membrane;GO:0014704//intercalated disc;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0030315//T-tubule;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005901//caveola;GO:0001518//voltage-gated sodium channel complex;GO:0042383//sarcolemma,GO:0086004//regulation of cardiac muscle cell contraction;GO:1902305//regulation of sodium ion transmembrane transport;GO:0050679//positive regulation of epithelial cell proliferation;GO:0019228//neuronal action potential;GO:0086067//AV node cell to bundle of His cell communication;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0086046//membrane depolarization during SA node cell action potential;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0035725//sodium ion transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0060048//cardiac muscle contraction;GO:0010765//positive regulation of sodium ion transport;GO:0021549//cerebellum development;GO:0086010//membrane depolarization during action potential;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0086005//ventricular cardiac muscle cell action potential;GO:0003231//cardiac ventricle development;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:0003360//brainstem development;GO:0045760//positive regulation of action potential;GO:0002027//regulation of heart rate;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0051899//membrane depolarization;GO:0042475//odontogenesis of dentin-containing tooth;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0006814//sodium ion transport;GO:0086070//SA node cell to atrial cardiac muscle cell communication;GO:0021537//telencephalon development,GO:0005248//voltage-gated sodium channel activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0030506//ankyrin binding;GO:0050998//nitric-oxide synthase binding;GO:0086006//voltage-gated sodium channel activity involved in cardiac muscle cell action potential;GO:0005516//calmodulin binding;GO:0019899//enzyme binding;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding;GO:0097110//scaffold protein binding,-
6332,2,0,27,0,0,4,21,49,46,0,1,0,"SCN7A;sodium channel, voltage-gated, type VII, alpha subunit",GO:0005886//plasma membrane;GO:0097386//glial cell projection;GO:0001518//voltage-gated sodium channel complex,GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0006936//muscle contraction;GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0055078//sodium ion homeostasis,GO:0005248//voltage-gated sodium channel activity,-
6334,0,0,51,0,8,39,115,0,52,0,0,0,"SCN8A;sodium channel, voltage gated, type VIII, alpha subunit",GO:0030018//Z disc;GO:0043025//neuronal cell body;GO:0033268//node of Ranvier;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0001518//voltage-gated sodium channel complex;GO:0043194//axon initial segment,GO:0042552//myelination;GO:0050905//neuromuscular process;GO:0007422//peripheral nervous system development;GO:0007628//adult walking behavior;GO:0019228//neuronal action potential;GO:0007517//muscle organ development;GO:0007411//axon guidance;GO:0035725//sodium ion transmembrane transport;GO:0007399//nervous system development;GO:0034765//regulation of ion transmembrane transport;GO:0007605//sensory perception of sound;GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0009636//response to toxic substance,GO:0005248//voltage-gated sodium channel activity;GO:0005524//ATP binding,-
6335,117,0,0,0,0,0,60,0,58,0,4,0,"SCN9A;sodium channel, voltage-gated, type IX, alpha subunit",GO:0001518//voltage-gated sodium channel complex;GO:0005886//plasma membrane,GO:0006954//inflammatory response;GO:0006814//sodium ion transport;GO:0086010//membrane depolarization during action potential;GO:0009636//response to toxic substance;GO:0009791//post-embryonic development;GO:0034765//regulation of ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0019228//neuronal action potential;GO:0048266//behavioral response to pain,GO:0031402//sodium ion binding;GO:0005248//voltage-gated sodium channel activity,-
6336,3,0,0,0,0,22,0,0,64,0,0,0,"SCN10A;sodium channel, voltage-gated, type X, alpha subunit",GO:0070062//extracellular vesicular exosome;GO:0044299//C-fiber;GO:0001518//voltage-gated sodium channel complex,GO:0002027//regulation of heart rate;GO:0035725//sodium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0086067//AV node cell to bundle of His cell communication;GO:0019228//neuronal action potential;GO:0019233//sensory perception of pain;GO:0086069//bundle of His cell to Purkinje myocyte communication;GO:0086010//membrane depolarization during action potential;GO:0006814//sodium ion transport;GO:0007600//sensory perception;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0055117//regulation of cardiac muscle contraction,GO:0005248//voltage-gated sodium channel activity,-
6337,193,0,0,5,1,30,0,0,40,0,8,364,"SCNN1A;sodium channel, non-voltage-gated 1 alpha subunit",GO:0005887//integral component of plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0005829//cytosol;GO:0034706//sodium channel complex;GO:0031514//motile cilium;GO:0060170//ciliary membrane;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0007588//excretion;GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0050896//response to stimulus;GO:0055078//sodium ion homeostasis;GO:0006814//sodium ion transport;GO:0050891//multicellular organismal water homeostasis,GO:0015280//ligand-gated sodium channel activity;GO:0003779//actin binding;GO:0050699//WW domain binding;GO:0005515//protein binding,K04824//Taste transduction;Aldosterone-regulated sodium reabsorption
6338,0,0,0,0,0,0,0,0,13,0,10,0,"SCNN1B;sodium channel, non-voltage-gated 1, beta subunit",GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0034706//sodium channel complex;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:0007588//excretion;GO:0050909//sensory perception of taste;GO:0050896//response to stimulus;GO:0006814//sodium ion transport;GO:0050891//multicellular organismal water homeostasis;GO:0055078//sodium ion homeostasis,GO:0015280//ligand-gated sodium channel activity;GO:0050699//WW domain binding;GO:0005515//protein binding,K04825//Aldosterone-regulated sodium reabsorption;Taste transduction
6339,37,0,0,0,0,33,43,34,0,0,0,0,"SCNN1D;sodium channel, non-voltage-gated 1, delta subunit",GO:0015629//actin cytoskeleton;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0050896//response to stimulus;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0006814//sodium ion transport,GO:0015280//ligand-gated sodium channel activity;GO:0005515//protein binding,-
634,0,3,0,0,2,0,8,0,28,0,0,0,CEACAM1;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein),GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0016477//cell migration;GO:0001525//angiogenesis;GO:0007229//integrin-mediated signaling pathway;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
6340,42,0,0,0,0,0,64,0,6,159,0,0,"SCNN1G;sodium channel, non-voltage-gated 1, gamma subunit",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0034706//sodium channel complex;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055078//sodium ion homeostasis;GO:0006814//sodium ion transport;GO:0050891//multicellular organismal water homeostasis;GO:0050896//response to stimulus;GO:0007588//excretion;GO:0050909//sensory perception of taste;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport,GO:0015280//ligand-gated sodium channel activity;GO:0050699//WW domain binding;GO:0005272//sodium channel activity;GO:0005515//protein binding,K04827//Aldosterone-regulated sodium reabsorption;Taste transduction
6341,0,1,1,0,12,0,0,0,55,0,28,0,SCO1;SCO1 cytochrome c oxidase assembly protein,GO:0005739//mitochondrion;GO:0030016//myofibril;GO:0005743//mitochondrial inner membrane,GO:0006825//copper ion transport;GO:0008535//respiratory chain complex IV assembly;GO:0006091//generation of precursor metabolites and energy;GO:0006878//cellular copper ion homeostasis,GO:0005507//copper ion binding,-
6342,0,96,24,144,324,14,0,0,27,0,63,0,SCP2;sterol carrier protein 2,GO:0005634//nucleus;GO:0005782//peroxisomal matrix;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005777//peroxisome;GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0006701//progesterone biosynthetic process;GO:0007031//peroxisome organization;GO:0036109//alpha-linolenic acid metabolic process;GO:0008206//bile acid metabolic process;GO:0072659//protein localization to plasma membrane;GO:1901373//lipid hydroperoxide transport;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0006869//lipid transport;GO:0032385//positive regulation of intracellular cholesterol transport;GO:0015914//phospholipid transport;GO:0045940//positive regulation of steroid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0032959//inositol trisphosphate biosynthetic process,GO:0033814//propanoyl-CoA C-acyltransferase activity;GO:0015485//cholesterol binding;GO:0005102//receptor binding;GO:0008526//phosphatidylinositol transporter activity;GO:0036042//long-chain fatty acyl-CoA binding;GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding;GO:0070538//oleic acid binding,K08764//Peroxisome;Metabolic pathways;Primary bile acid biosynthesis;PPAR signaling pathway
6343,0,0,0,0,15,0,0,0,0,0,0,0,SCT;secretin,GO:0005576//extracellular region,GO:0097150//neuronal stem cell maintenance;GO:0030157//pancreatic juice secretion;GO:0008542//visual learning;GO:0021542//dentate gyrus development;GO:0043524//negative regulation of neuron apoptotic process,GO:0005179//hormone activity,-
6344,73,0,0,0,0,0,0,0,43,0,7,0,SCTR;secretin receptor,GO:0005887//integral component of plasma membrane;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane,GO:0007586//digestion;GO:0007588//excretion;GO:0007186//G-protein coupled receptor signaling pathway,GO:0015055//secretin receptor activity,K04588//Neuroactive ligand-receptor interaction;Bile secretion;Pancreatic secretion
6345,0,0,31,0,0,28,10,1,51,0,0,0,SRL;sarcalumenin,GO:0033018//sarcoplasmic reticulum lumen,GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding,K12483//Endocytosis
6346,0,0,0,0,0,8,0,0,20,0,0,0,CCL1;chemokine (C-C motif) ligand 1,GO:0005615//extracellular space,GO:0060326//cell chemotaxis;GO:0007165//signal transduction;GO:0006935//chemotaxis;GO:0016032//viral process;GO:0006955//immune response;GO:0006874//cellular calcium ion homeostasis,GO:0008009//chemokine activity,K05514//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
635,0,0,45,0,39,0,0,0,37,0,6,0,BHMT;betaine--homocysteine S-methyltransferase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0000096//sulfur amino acid metabolic process;GO:0006479//protein methylation;GO:0046500//S-adenosylmethionine metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006579//amino-acid betaine catabolic process;GO:0071267//L-methionine salvage;GO:0050666//regulation of homocysteine metabolic process;GO:0044281//small molecule metabolic process;GO:0010243//response to organonitrogen compound;GO:0006577//amino-acid betaine metabolic process,GO:0008270//zinc ion binding;GO:0047150//betaine-homocysteine S-methyltransferase activity;GO:0032403//protein complex binding;GO:0008898//S-adenosylmethionine-homocysteine S-methyltransferase activity,"K00544//Metabolic pathways;Glycine, serine and threonine metabolism;Cysteine and methionine metabolism"
6354,69,0,0,0,0,0,0,0,0,0,0,0,CCL7;chemokine (C-C motif) ligand 7,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0006954//inflammatory response;GO:0006874//cellular calcium ion homeostasis;GO:0007267//cell-cell signaling;GO:0048245//eosinophil chemotaxis;GO:0007165//signal transduction;GO:0010332//response to gamma radiation;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0007010//cytoskeleton organization;GO:0002548//monocyte chemotaxis;GO:0030335//positive regulation of cell migration;GO:0071361//cellular response to ethanol;GO:0008360//regulation of cell shape,GO:0008009//chemokine activity;GO:0031727//CCR2 chemokine receptor binding;GO:0031726//CCR1 chemokine receptor binding;GO:0008201//heparin binding,K05509//Asthma;Chemokine signaling pathway;NF-kappa B signaling pathway;Cytokine-cytokine receptor interaction
6355,22,0,0,0,0,21,0,0,0,0,0,0,CCL8;chemokine (C-C motif) ligand 8,GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:0006874//cellular calcium ion homeostasis;GO:0007267//cell-cell signaling;GO:0060326//cell chemotaxis;GO:0007165//signal transduction;GO:0043085//positive regulation of catalytic activity;GO:0006935//chemotaxis;GO:0006887//exocytosis;GO:0006955//immune response;GO:0009615//response to virus;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport,GO:0004672//protein kinase activity;GO:0008201//heparin binding;GO:0016004//phospholipase activator activity;GO:0008009//chemokine activity,K14624//Influenza A;NOD-like receptor signaling pathway;Rheumatoid arthritis;Chemokine signaling pathway;Malaria;Chagas disease (American trypanosomiasis);Cytokine-cytokine receptor interaction;Herpes simplex infection;K05509//Asthma;Cytokine-cytokine receptor interaction;NF-kappa B signaling pathway;Chemokine signaling pathway
636,0,0,1,0,44,12,0,0,54,0,0,0,BICD1;bicaudal D homolog 1 (Drosophila),GO:0016020//membrane;GO:0005881//cytoplasmic microtubule;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle;GO:0005802//trans-Golgi network;GO:0072517//host cell viral assembly compartment;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0045298//tubulin complex;GO:0048471//perinuclear region of cytoplasm,GO:1900275//negative regulation of phospholipase C activity;GO:0008298//intracellular mRNA localization;GO:0072393//microtubule anchoring at microtubule organizing center;GO:0006396//RNA processing;GO:0016032//viral process;GO:0072385//minus-end-directed organelle transport along microtubule;GO:0034063//stress granule assembly;GO:0033365//protein localization to organelle;GO:1900276//regulation of proteinase activated receptor activity;GO:0009653//anatomical structure morphogenesis;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:1900737//negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0045502//dynein binding;GO:0008093//cytoskeletal adaptor activity;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0017137//Rab GTPase binding;GO:0034452//dynactin binding;GO:0031871//proteinase activated receptor binding,K12478//Tuberculosis;Phagosome;Endocytosis;K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
6360,0,0,0,0,0,0,0,0,17,0,14,0,CCL16;chemokine (C-C motif) ligand 16,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0060326//cell chemotaxis;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0006935//chemotaxis;GO:0007154//cell communication;GO:0006955//immune response;GO:0050918//positive chemotaxis,GO:0042056//chemoattractant activity;GO:0008009//chemokine activity,K05514//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
6361,0,0,0,0,0,0,0,0,15,0,0,0,CCL17;chemokine (C-C motif) ligand 17,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0060326//cell chemotaxis;GO:0007275//multicellular organismal development;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005102//receptor binding;GO:0008009//chemokine activity;GO:0031729//CCR4 chemokine receptor binding,K05514//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
6362,0,0,0,0,0,0,0,0,22,0,0,0,CCL18;chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated),GO:0005615//extracellular space,GO:0007154//cell communication;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response;GO:0009607//response to biotic stimulus;GO:0007165//signal transduction;GO:0060326//cell chemotaxis;GO:0006955//immune response;GO:0006935//chemotaxis,GO:0005515//protein binding;GO:0008009//chemokine activity,K05408//Toll-like receptor signaling pathway;Chagas disease (American trypanosomiasis);Chemokine signaling pathway;Cytokine-cytokine receptor interaction;Rheumatoid arthritis;Salmonella infection;K05514//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
6363,0,0,0,0,0,0,0,6,0,0,0,0,CCL19;chemokine (C-C motif) ligand 19,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006874//cellular calcium ion homeostasis;GO:0031295//T cell costimulation;GO:0007154//cell communication;GO:0001768//establishment of T cell polarity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0001771//immunological synapse formation;GO:0060491//regulation of cell projection assembly;GO:0002408//myeloid dendritic cell chemotaxis;GO:0043089//positive regulation of Cdc42 GTPase activity;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0042102//positive regulation of T cell proliferation;GO:0006954//inflammatory response;GO:0045860//positive regulation of protein kinase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0032320//positive regulation of Ras GTPase activity;GO:0007257//activation of JUN kinase activity;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0097029//mature dendritic cell differentiation;GO:0048469//cell maturation;GO:0034695//response to prostaglandin E;GO:0051897//positive regulation of protein kinase B signaling;GO:2000147//positive regulation of cell motility;GO:0006955//immune response;GO:0051209//release of sequestered calcium ion into cytosol;GO:0050921//positive regulation of chemotaxis;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0009615//response to virus;GO:0046330//positive regulation of JNK cascade;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0071731//response to nitric oxide;GO:0014070//response to organic cyclic compound;GO:0002407//dendritic cell chemotaxis;GO:2000549//positive regulation of dendritic cell dendrite assembly;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0032735//positive regulation of interleukin-12 production;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0072610//interleukin-12 secretion;GO:0045807//positive regulation of endocytosis,GO:0042379//chemokine receptor binding;GO:0031735//CCR10 chemokine receptor binding;GO:0008009//chemokine activity;GO:0031732//CCR7 chemokine receptor binding;GO:0048020//CCR chemokine receptor binding,K05512//Chemokine signaling pathway;Cytokine-cytokine receptor interaction;NF-kappa B signaling pathway
6366,0,0,0,4,0,0,12,71,10,0,18,0,CCL21;chemokine (C-C motif) ligand 21,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0001768//establishment of T cell polarity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031529//ruffle organization;GO:0031295//T cell costimulation;GO:2000406//positive regulation of T cell migration;GO:0035759//mesangial cell-matrix adhesion;GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:2000529//positive regulation of myeloid dendritic cell chemotaxis;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0001771//immunological synapse formation;GO:0045860//positive regulation of protein kinase activity;GO:0006954//inflammatory response;GO:0030838//positive regulation of actin filament polymerization;GO:2000548//negative regulation of dendritic cell dendrite assembly;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0031274//positive regulation of pseudopodium assembly;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0060326//cell chemotaxis;GO:2000147//positive regulation of cell motility;GO:0048469//cell maturation;GO:0034695//response to prostaglandin E;GO:0051897//positive regulation of protein kinase B signaling;GO:0046330//positive regulation of JNK cascade;GO:0032862//activation of Rho GTPase activity;GO:0001954//positive regulation of cell-matrix adhesion;GO:0050921//positive regulation of chemotaxis;GO:0051209//release of sequestered calcium ion into cytosol;GO:0006955//immune response;GO:0010560//positive regulation of glycoprotein biosynthetic process;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0002407//dendritic cell chemotaxis;GO:0051491//positive regulation of filopodium assembly;GO:0048260//positive regulation of receptor-mediated endocytosis,GO:0031732//CCR7 chemokine receptor binding;GO:0008009//chemokine activity;GO:0042379//chemokine receptor binding,K16062//Chemokine signaling pathway;Cytokine-cytokine receptor interaction;NF-kappa B signaling pathway
6367,49,0,0,0,0,0,25,0,28,0,7,0,CCL22;chemokine (C-C motif) ligand 22,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0009615//response to virus;GO:0060326//cell chemotaxis;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response;GO:0006955//immune response;GO:0006935//chemotaxis,GO:0008009//chemokine activity,K05514//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
6368,0,0,0,0,0,0,0,0,0,0,6,0,CCL23;chemokine (C-C motif) ligand 23,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006955//immune response;GO:0006935//chemotaxis;GO:2001264//negative regulation of C-C chemokine binding;GO:0002548//monocyte chemotaxis;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0006874//cellular calcium ion homeostasis;GO:0006954//inflammatory response;GO:0007165//signal transduction,GO:0008009//chemokine activity;GO:0008201//heparin binding;GO:0031726//CCR1 chemokine receptor binding,K05511//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
637,0,114,26,113,64,0,0,0,7,0,68,0,BID;BH3 interacting domain death agonist,GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0032592//integral component of mitochondrial membrane,GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0032355//response to estradiol;GO:0042770//signal transduction in response to DNA damage;GO:0090150//establishment of protein localization to membrane;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0042127//regulation of cell proliferation;GO:0032461//positive regulation of protein oligomerization;GO:0001836//release of cytochrome c from mitochondria;GO:0008637//apoptotic mitochondrial changes;GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0006626//protein targeting to mitochondrion;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032464//positive regulation of protein homooligomerization;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0051260//protein homooligomerization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097193//intrinsic apoptotic signaling pathway;GO:0034349//glial cell apoptotic process;GO:0007420//brain development;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0051402//neuron apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0005123//death receptor binding,K04726//p53 signaling pathway;Viral myocarditis;Apoptosis;Natural killer cell mediated cytotoxicity;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;Tuberculosis;Pathways in cancer
6370,0,0,0,0,0,0,9,0,13,0,0,0,CCL25;chemokine (C-C motif) ligand 25,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006954//inflammatory response;GO:0050900//leukocyte migration;GO:0060326//cell chemotaxis;GO:0001954//positive regulation of cell-matrix adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008009//chemokine activity;GO:0005179//hormone activity;GO:0031735//CCR10 chemokine receptor binding;GO:0042379//chemokine receptor binding,K13072//Chemokine signaling pathway;Cytokine-cytokine receptor interaction;Intestinal immune network for IgA production
6372,0,0,0,0,0,14,0,0,26,0,0,0,CXCL6;chemokine (C-X-C motif) ligand 6,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006935//chemotaxis;GO:0006955//immune response;GO:0006954//inflammatory response;GO:0007267//cell-cell signaling;GO:0060326//cell chemotaxis;GO:0042742//defense response to bacterium;GO:0007165//signal transduction,GO:0008009//chemokine activity;GO:0008201//heparin binding,K05506//Cytokine-cytokine receptor interaction;Rheumatoid arthritis;Chemokine signaling pathway;Pertussis
6374,0,0,0,0,0,0,22,0,19,0,4,0,CXCL5;chemokine (C-X-C motif) ligand 5,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007267//cell-cell signaling;GO:0008284//positive regulation of cell proliferation;GO:0006955//immune response;GO:0006935//chemotaxis;GO:0007165//signal transduction;GO:0060326//cell chemotaxis,GO:0008009//chemokine activity,K05506//Rheumatoid arthritis;Cytokine-cytokine receptor interaction;Chemokine signaling pathway;Pertussis
6375,0,0,0,0,0,5,0,0,17,0,0,0,XCL1;chemokine (C motif) ligand 1,GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0010820//positive regulation of T cell chemotaxis;GO:2000566//positive regulation of CD8-positive, alpha-beta T cell proliferation;GO:2000503//positive regulation of natural killer cell chemotaxis;GO:0071353//cellular response to interleukin-4;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0002725//negative regulation of T cell cytokine production;GO:2000518//negative regulation of T-helper 1 cell activation;GO:2000412//positive regulation of thymocyte migration;GO:0051209//release of sequestered calcium ion into cytosol;GO:0006955//immune response;GO:2000558//positive regulation of immunoglobulin production in mucosal tissue;GO:0009615//response to virus;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0032703//negative regulation of interleukin-2 production;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:2000538//positive regulation of B cell chemotaxis;GO:0032689//negative regulation of interferon-gamma production;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0071663//positive regulation of granzyme B production;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:0035782//mature natural killer cell chemotaxis;GO:2000513//positive regulation of granzyme A production;GO:2000563//positive regulation of CD4-positive, alpha-beta T cell proliferation;GO:0007165//signal transduction;GO:0002726//positive regulation of T cell cytokine production;GO:0030593//neutrophil chemotaxis;GO:0050727//regulation of inflammatory response;GO:0032733//positive regulation of interleukin-10 production;GO:2000556//positive regulation of T-helper 1 cell cytokine production;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0007267//cell-cell signaling;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0071636//positive regulation of transforming growth factor beta production;GO:0002826//negative regulation of T-helper 1 type immune response",GO:0008009//chemokine activity;GO:0042803//protein homodimerization activity;GO:0042379//chemokine receptor binding,K05507//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
6376,0,0,0,0,0,30,0,0,26,0,0,0,CX3CL1;chemokine (C-X3-C motif) ligand 1,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0030593//neutrophil chemotaxis;GO:0006955//immune response;GO:0060055//angiogenesis involved in wound healing;GO:0006952//defense response;GO:0045766//positive regulation of angiogenesis;GO:0006935//chemotaxis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0050729//positive regulation of inflammatory response;GO:0007155//cell adhesion;GO:0019221//cytokine-mediated signaling pathway;GO:0048246//macrophage chemotaxis;GO:0030595//leukocyte chemotaxis;GO:0048247//lymphocyte chemotaxis;GO:0051041//positive regulation of calcium-independent cell-cell adhesion;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0050902//leukocyte adhesive activation,GO:0008009//chemokine activity;GO:0005102//receptor binding;GO:0005515//protein binding,K05508//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
638,0,0,3,0,8,0,17,2,2,0,0,0,BIK;BCL2-interacting killer (apoptosis-inducing),GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane,GO:0008637//apoptotic mitochondrial changes;GO:0006915//apoptotic process;GO:0007283//spermatogenesis;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008584//male gonad development;GO:0032464//positive regulation of protein homooligomerization,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0051400//BH domain binding,-
6382,0,0,27,0,13,0,0,0,0,0,6,0,SDC1;syndecan 1,GO:0005796//Golgi lumen;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0043202//lysosomal lumen,"GO:0051592//response to calcium ion;GO:0001657//ureteric bud development;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0042476//odontogenesis;GO:0006954//inflammatory response;GO:0042157//lipoprotein metabolic process;GO:0051591//response to cAMP;GO:0042542//response to hydrogen peroxide;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0055002//striated muscle cell development;GO:0060070//canonical Wnt signaling pathway;GO:0042060//wound healing;GO:0007603//phototransduction, visible light;GO:0051384//response to glucocorticoid;GO:0006024//glycosaminoglycan biosynthetic process;GO:0009636//response to toxic substance;GO:0044281//small molecule metabolic process;GO:0001523//retinoid metabolic process;GO:0048627//myoblast development;GO:0060009//Sertoli cell development;GO:0030198//extracellular matrix organization",GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0008092//cytoskeletal protein binding;GO:0001948//glycoprotein binding,K06257//ECM-receptor interaction;Malaria;Cell adhesion molecules (CAMs)
63826,0,382,345,442,695,8,0,92,16,0,347,0,SRR;serine racemase,GO:0045177//apical part of cell;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0043278//response to morphine;GO:0007568//aging;GO:0051289//protein homotetramerization;GO:0042493//response to drug;GO:0070179//D-serine biosynthetic process;GO:0032496//response to lipopolysaccharide;GO:0006563//L-serine metabolic process;GO:0007420//brain development;GO:0042866//pyruvate biosynthetic process,GO:0005524//ATP binding;GO:0008721//D-serine ammonia-lyase activity;GO:0030170//pyridoxal phosphate binding;GO:0030165//PDZ domain binding;GO:0000287//magnesium ion binding;GO:0030378//serine racemase activity;GO:0016594//glycine binding;GO:0003941//L-serine ammonia-lyase activity;GO:0005509//calcium ion binding;GO:0018114//threonine racemase activity;GO:0042803//protein homodimerization activity,"K12235//Glycine, serine and threonine metabolism"
63827,0,0,0,0,0,9,6,105,0,0,0,0,BCAN;brevican,GO:0005578//proteinaceous extracellular matrix;GO:0043202//lysosomal lumen;GO:0031225//anchored component of membrane;GO:0005576//extracellular region;GO:0005796//Golgi lumen,GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0005975//carbohydrate metabolic process;GO:0030207//chondroitin sulfate catabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0022617//extracellular matrix disassembly;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0021766//hippocampus development,GO:0030246//carbohydrate binding;GO:0005540//hyaluronic acid binding,-
6383,0,0,0,0,20,30,0,0,22,0,1,0,SDC2;syndecan 2,GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043202//lysosomal lumen;GO:0043025//neuronal cell body,"GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030198//extracellular matrix organization;GO:0031000//response to caffeine;GO:0005975//carbohydrate metabolic process;GO:0001523//retinoid metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0048813//dendrite morphogenesis;GO:0042060//wound healing;GO:0001666//response to hypoxia;GO:0007603//phototransduction, visible light;GO:0048814//regulation of dendrite morphogenesis",GO:0005515//protein binding;GO:0008092//cytoskeletal protein binding;GO:0030165//PDZ domain binding,K06257//ECM-receptor interaction;Cell adhesion molecules (CAMs);Malaria
6385,0,0,0,11,0,13,18,0,19,0,0,0,SDC4;syndecan 4,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0043034//costamere;GO:0009986//cell surface;GO:0043202//lysosomal lumen;GO:0005925//focal adhesion;GO:0005796//Golgi lumen;GO:0005887//integral component of plasma membrane,"GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0045860//positive regulation of protein kinase activity;GO:0001657//ureteric bud development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030198//extracellular matrix organization;GO:0005975//carbohydrate metabolic process;GO:0051496//positive regulation of stress fiber assembly;GO:0001523//retinoid metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0007603//phototransduction, visible light;GO:0051894//positive regulation of focal adhesion assembly",GO:0005515//protein binding;GO:0070053//thrombospondin receptor activity;GO:0001968//fibronectin binding;GO:0005080//protein kinase C binding;GO:0008092//cytoskeletal protein binding,K06257//ECM-receptor interaction;Malaria;Cell adhesion molecules (CAMs)
6386,0,70,2,13,91,0,0,0,0,0,0,0,SDCBP;syndecan binding protein (syntenin),GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0005789//endoplasmic reticulum membrane;GO:0005912//adherens junction;GO:0005634//nucleus;GO:0016020//membrane;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005895//interleukin-5 receptor complex;GO:0005856//cytoskeleton,"GO:0006612//protein targeting to membrane;GO:0007265//Ras protein signal transduction;GO:0042327//positive regulation of phosphorylation;GO:0006930//substrate-dependent cell migration, cell extension;GO:0030036//actin cytoskeleton organization;GO:0035556//intracellular signal transduction;GO:0007268//synaptic transmission;GO:0046330//positive regulation of JNK cascade;GO:0007411//axon guidance",GO:0047485//protein N-terminus binding;GO:0001948//glycoprotein binding;GO:0046875//ephrin receptor binding;GO:0005109//frizzled binding;GO:0005137//interleukin-5 receptor binding;GO:0042802//identical protein binding;GO:0050839//cell adhesion molecule binding;GO:0019838//growth factor binding;GO:0042043//neurexin family protein binding;GO:0008022//protein C-terminus binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity;GO:0045545//syndecan binding,-
6387,0,0,0,0,17,51,0,0,36,0,10,0,CXCL12;chemokine (C-X-C motif) ligand 12,GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0042098//T cell proliferation;GO:0060326//cell chemotaxis;GO:0090026//positive regulation of monocyte chemotaxis;GO:0006955//immune response;GO:0050930//induction of positive chemotaxis;GO:0022029//telencephalon cell migration;GO:0008045//motor neuron axon guidance;GO:0009615//response to virus;GO:0008344//adult locomotory behavior;GO:0001569//patterning of blood vessels;GO:0045666//positive regulation of neuron differentiation;GO:0001764//neuron migration;GO:0006935//chemotaxis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0007155//cell adhesion;GO:0007281//germ cell development;GO:0031100//organ regeneration;GO:0033603//positive regulation of dopamine secretion;GO:2000406//positive regulation of T cell migration;GO:0006874//cellular calcium ion homeostasis;GO:0001667//ameboidal cell migration;GO:0009408//response to heat;GO:0001938//positive regulation of endothelial cell proliferation;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008064//regulation of actin polymerization or depolymerization;GO:0007165//signal transduction;GO:0008015//blood circulation;GO:0045785//positive regulation of cell adhesion;GO:0008354//germ cell migration;GO:0009314//response to radiation;GO:2000107//negative regulation of leukocyte apoptotic process;GO:0090280//positive regulation of calcium ion import;GO:0009612//response to mechanical stimulus;GO:0001666//response to hypoxia;GO:0070098//chemokine-mediated signaling pathway;GO:0043434//response to peptide hormone,GO:0008009//chemokine activity;GO:0045236//CXCR chemokine receptor binding;GO:0005102//receptor binding;GO:0008083//growth factor activity;GO:0042379//chemokine receptor binding,K10031//Intestinal immune network for IgA production;Leukocyte transendothelial migration;Cytokine-cytokine receptor interaction;Rheumatoid arthritis;NF-kappa B signaling pathway;Chemokine signaling pathway;Axon guidance
63874,0,0,0,0,3,0,0,42,8,0,9,0,ABHD4;abhydrolase domain containing 4,-,GO:0016042//lipid catabolic process,GO:0016787//hydrolase activity,-
63875,0,41,67,6,5,0,0,3,57,0,7,0,MRPL17;mitochondrial ribosomal protein L17,GO:0005743//mitochondrial inner membrane;GO:0005840//ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0019904//protein domain specific binding,-
63876,0,0,0,12,37,0,13,0,11,0,0,0,PKNOX2;PBX/knotted 1 homeobox 2,GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015629//actin cytoskeleton,GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003785//actin monomer binding;GO:0003677//DNA binding;GO:0051015//actin filament binding;GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer
63877,0,2,19,6,39,0,0,8,13,0,5,0,"FAM204A;family with sequence similarity 204, member A",-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
6388,0,0,0,1,18,7,0,1,0,0,12,0,SDF2;stromal cell-derived factor 2,GO:0016020//membrane;GO:0005615//extracellular space,GO:0035269//protein O-linked mannosylation;GO:0006486//protein glycosylation,GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity,K00728//Other types of O-glycan biosynthesis
6389,0,29,0,8,35,0,4,0,55,0,0,0,"SDHA;succinate dehydrogenase complex, subunit A, flavoprotein (Fp)",GO:0005749//mitochondrial respiratory chain complex II;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0007399//nervous system development;GO:0044281//small molecule metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0006105//succinate metabolic process;GO:0022904//respiratory electron transport chain;GO:0055114//oxidation-reduction process,GO:0050660//flavin adenine dinucleotide binding;GO:0008177//succinate dehydrogenase (ubiquinone) activity;GO:0005515//protein binding;GO:0000104//succinate dehydrogenase activity,K00234//Biosynthesis of secondary metabolites;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Citrate cycle (TCA cycle);Metabolic pathways
63891,0,409,499,654,1080,27,48,132,69,0,962,3,RNF123;ring finger protein 123,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
63892,184,0,0,0,0,10,0,0,44,193,36,0,THADA;thyroid adenoma associated,-,-,-,-
63893,0,0,0,27,21,27,0,78,67,0,0,0,UBE2O;ubiquitin-conjugating enzyme E2O,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0070534//protein K63-linked ubiquitination;GO:0006513//protein monoubiquitination;GO:0042147//retrograde transport, endosome to Golgi;GO:0030513//positive regulation of BMP signaling pathway",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K10581//Ubiquitin mediated proteolysis
63894,0,0,0,0,11,0,12,0,22,0,0,0,"VIPAS39;VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog",GO:0030897//HOPS complex;GO:0005737//cytoplasm;GO:0055037//recycling endosome;GO:0005769//early endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005770//late endosome,"GO:0007283//spermatogenesis;GO:0006886//intracellular protein transport;GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0008333//endosome to lysosome transport",GO:0005515//protein binding,K00654//Sphingolipid metabolism;Metabolic pathways
63895,0,0,0,0,0,0,16,189,115,0,15,0,PIEZO2;piezo-type mechanosensitive ion channel component 2,GO:0016021//integral component of membrane,GO:0050974//detection of mechanical stimulus involved in sensory perception;GO:0042391//regulation of membrane potential;GO:0006812//cation transport;GO:0009612//response to mechanical stimulus,GO:0005261//cation channel activity;GO:0008381//mechanically-gated ion channel activity,-
63897,33,30,0,0,33,18,0,0,41,27,1,0,HEATR6;HEAT repeat containing 6,-,-,GO:0044822//poly(A) RNA binding,-
63898,0,58,1,0,27,0,0,125,26,2,0,0,SH2D4A;SH2 domain containing 4A,GO:0005737//cytoplasm,GO:0010923//negative regulation of phosphatase activity,GO:0019902//phosphatase binding;GO:0005515//protein binding,K07901//Pancreatic secretion;K08273//VEGF signaling pathway
63899,0,26,0,13,8,0,47,0,26,0,0,0,"NSUN3;NOP2/Sun domain family, member 3",-,GO:0032259//methylation,GO:0003723//RNA binding;GO:0008168//methyltransferase activity,-
639,0,1,0,0,16,10,0,5,83,0,9,0,"PRDM1;PR domain containing 1, with ZNF domain",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045579//positive regulation of B cell differentiation;GO:0032259//methylation;GO:0009791//post-embryonic development;GO:0042462//eye photoreceptor cell development;GO:0060707//trophoblast giant cell differentiation;GO:0030889//negative regulation of B cell proliferation;GO:0045165//cell fate commitment;GO:0007281//germ cell development;GO:0031665//negative regulation of lipopolysaccharide-mediated signaling pathway;GO:0010628//positive regulation of gene expression;GO:0001893//maternal placenta development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060576//intestinal epithelial cell development;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042826//histone deacetylase binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008168//methyltransferase activity,-
6390,0,0,0,0,10,0,31,68,22,0,1,0,"SDHB;succinate dehydrogenase complex, subunit B, iron sulfur (Ip)",GO:0005749//mitochondrial respiratory chain complex II;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0009060//aerobic respiration;GO:0006099//tricarboxylic acid cycle;GO:0006105//succinate metabolic process;GO:0022904//respiratory electron transport chain,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0008177//succinate dehydrogenase (ubiquinone) activity;GO:0048039//ubiquinone binding;GO:0009055//electron carrier activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0051538//3 iron, 4 sulfur cluster binding",K00235//Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways;Citrate cycle (TCA cycle);Biosynthesis of secondary metabolites
63901,0,0,0,111,104,21,0,0,14,0,2,0,"FAM111A;family with sequence similarity 111, member A",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000785//chromatin,GO:0051607//defense response to virus;GO:0016032//viral process;GO:0045071//negative regulation of viral genome replication;GO:0006260//DNA replication,GO:0003824//catalytic activity;GO:0005515//protein binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
63905,0,0,0,0,0,0,62,0,17,0,0,0,"MANBAL;mannosidase, beta A, lysosomal-like",GO:0016021//integral component of membrane,-,-,-
63906,0,0,0,0,1,0,0,3,23,1,0,0,GPATCH3;G patch domain containing 3,-,-,GO:0003676//nucleic acid binding,-
63908,0,0,0,8,5,21,0,0,20,0,0,0,"NAPB;N-ethylmaleimide-sensitive factor attachment protein, beta",GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070062//extracellular vesicular exosome,"GO:0035249//synaptic transmission, glutamatergic;GO:0035494//SNARE complex disassembly;GO:0010807//regulation of synaptic vesicle priming;GO:0006886//intracellular protein transport",GO:0019905//syntaxin binding,K15296//Synaptic vesicle cycle
6391,0,65,0,24,14,32,0,0,56,0,0,0,"SDHC;succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005749//mitochondrial respiratory chain complex II,GO:0022904//respiratory electron transport chain;GO:0055114//oxidation-reduction process;GO:0006099//tricarboxylic acid cycle;GO:0009060//aerobic respiration;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,GO:0020037//heme binding;GO:0009055//electron carrier activity;GO:0046872//metal ion binding;GO:0000104//succinate dehydrogenase activity,K00236//Biosynthesis of secondary metabolites;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Citrate cycle (TCA cycle);Metabolic pathways
63910,0,1,0,0,0,0,27,1,0,0,8,0,"SLC17A9;solute carrier family 17 (vesicular nucleotide transporter), member 9",GO:0016021//integral component of membrane,GO:0006887//exocytosis;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
63916,0,1,0,26,34,9,0,0,0,0,7,257,ELMO2;engulfment and cell motility 2,GO:0005856//cytoskeleton;GO:0016020//membrane;GO:0005829//cytosol,GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0060326//cell chemotaxis;GO:0045087//innate immune response;GO:0006915//apoptotic process,GO:0030971//receptor tyrosine kinase binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding,K12366//Shigellosis;Bacterial invasion of epithelial cells;Chemokine signaling pathway
63917,0,39,1,18,76,0,0,0,10,0,4,0,GALNT11;polypeptide N-acetylgalactosaminyltransferase 11,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044267//cellular protein metabolic process;GO:0007220//Notch receptor processing;GO:0008593//regulation of Notch signaling pathway;GO:0007368//determination of left/right symmetry;GO:0061314//Notch signaling involved in heart development;GO:0018243//protein O-linked glycosylation via threonine;GO:0016266//O-glycan processing;GO:0060271//cilium morphogenesis;GO:0043687//post-translational protein modification,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0005112//Notch binding,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
6392,0,2,2,13,16,0,0,0,26,0,10,0,"SDHD;succinate dehydrogenase complex, subunit D, integral membrane protein",GO:0005749//mitochondrial respiratory chain complex II;GO:0005740//mitochondrial envelope;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0044281//small molecule metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0044237//cellular metabolic process;GO:0022904//respiratory electron transport chain,GO:0046872//metal ion binding;GO:0000104//succinate dehydrogenase activity;GO:0009055//electron carrier activity;GO:0048039//ubiquinone binding;GO:0020037//heme binding,K00237//Biosynthesis of secondary metabolites;Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways;Citrate cycle (TCA cycle)
63920,0,0,0,0,0,0,0,0,22,0,0,0,"ZBED8;zinc finger, BED-type containing 8",GO:0005739//mitochondrion,-,GO:0003676//nucleic acid binding,K06103//Tight junction
63922,0,0,0,0,0,17,0,3,12,0,27,0,"CHTF18;CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane,GO:0006260//DNA replication;GO:0007049//cell cycle,GO:0003677//DNA binding;GO:0005524//ATP binding,-
63923,0,0,0,0,0,18,0,0,18,0,5,279,TNN;tenascin N,GO:0009986//cell surface;GO:0005578//proteinaceous extracellular matrix,GO:0016049//cell growth;GO:0007160//cell-matrix adhesion;GO:0016477//cell migration;GO:0007409//axonogenesis,GO:0042802//identical protein binding;GO:0005178//integrin binding,K06252//Focal adhesion;ECM-receptor interaction
63924,91,0,0,0,0,9,0,0,0,0,11,0,CIDEC;cell death-inducing DFFA-like effector c,GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0034389//lipid particle organization;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0097194//execution phase of apoptosis;GO:0042981//regulation of apoptotic process",-,K02311//Apoptosis;K02310//Apoptosis
63925,0,0,0,0,0,12,5,72,25,2,0,0,ZNF335;zinc finger protein 335,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,"GO:0021895//cerebral cortex neuron differentiation;GO:0051569//regulation of histone H3-K4 methylation;GO:0050671//positive regulation of lymphocyte proliferation;GO:0002052//positive regulation of neuroblast proliferation;GO:0040029//regulation of gene expression, epigenetic;GO:0007420//brain development;GO:0048854//brain morphogenesis;GO:0080182//histone H3-K4 trimethylation;GO:0006351//transcription, DNA-templated;GO:0048812//neuron projection morphogenesis;GO:0050769//positive regulation of neurogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development",GO:0044212//transcription regulatory region DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
63926,0,0,0,0,42,0,0,0,27,0,0,0,ANKEF1;ankyrin repeat and EF-hand domain containing 1,-,-,GO:0005509//calcium ion binding,-
63928,0,0,0,0,0,15,0,0,60,0,0,0,CHP2;calcineurin-like EF-hand protein 2,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0015031//protein transport;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:0071277//cellular response to calcium ion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042307//positive regulation of protein import into nucleus;GO:0010922//positive regulation of phosphatase activity;GO:0008284//positive regulation of cell proliferation,GO:0005509//calcium ion binding;GO:0005515//protein binding,K06268//Glutamatergic synapse;T cell receptor signaling pathway;Apoptosis;Amphetamine addiction;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Wnt signaling pathway;Amyotrophic lateral sclerosis (ALS);Oocyte meiosis;Axon guidance;Tuberculosis;Long-term potentiation;Osteoclast differentiation;Alzheimer's disease;VEGF signaling pathway;HTLV-I infection;Calcium signaling pathway;B cell receptor signaling pathway
63929,0,1,46,11,47,39,0,11,67,0,0,2,"XPNPEP3;X-prolyl aminopeptidase (aminopeptidase P) 3, putative",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0003094//glomerular filtration;GO:0016485//protein processing,GO:0030145//manganese ion binding;GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity,-
63930,0,0,0,0,0,5,21,0,18,0,0,0,LOC63930;uncharacterized LOC63930,-,-,-,-
63931,0,1,0,9,39,12,46,0,0,0,0,0,MRPS14;mitochondrial ribosomal protein S14,GO:0031965//nuclear membrane;GO:0005761//mitochondrial ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,K11984//Spliceosome
63932,0,0,0,3,30,9,0,0,9,0,1,0,CXorf56;chromosome X open reading frame 56,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
63933,0,0,0,5,25,0,0,76,11,0,7,0,MCUR1;mitochondrial calcium uniporter regulator 1,GO:0031305//integral component of mitochondrial inner membrane,GO:0070509//calcium ion import;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0006851//mitochondrial calcium ion transport,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
63934,0,0,0,0,17,21,0,0,65,0,0,0,ZNF667;zinc finger protein 667,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
63935,0,0,0,6,0,11,22,0,23,133,36,0,PCIF1;PDX1 C-terminal inhibiting factor 1,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus,GO:0010923//negative regulation of phosphatase activity,-,-
63939,37,134,46,81,124,34,41,0,15,0,41,0,"FAM217B;family with sequence similarity 217, member B",-,-,-,K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
63941,0,1,1,4,15,0,8,31,55,0,0,295,NECAB3;N-terminal EF-hand calcium binding protein 3,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0000137//Golgi cis cisterna;GO:0005737//cytoplasm,GO:0042984//regulation of amyloid precursor protein biosynthetic process;GO:0009306//protein secretion;GO:0019538//protein metabolic process,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
63943,0,0,0,0,0,0,0,0,1,0,0,0,FKBPL;FK506 binding protein like,GO:0005789//endoplasmic reticulum membrane,GO:0000413//protein peptidyl-prolyl isomerization;GO:0009314//response to radiation;GO:0061077//chaperone-mediated protein folding,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0005528//FK506 binding,-
63946,0,0,94,16,0,0,35,102,44,0,0,1,DMRTC2;DMRT-like family C2,GO:0005634//nucleus;GO:0001741//XY body,"GO:1900111//positive regulation of histone H3-K9 dimethylation;GO:0006351//transcription, DNA-templated;GO:1900114//positive regulation of histone H3-K9 trimethylation;GO:0006355//regulation of transcription, DNA-templated;GO:0007290//spermatid nucleus elongation;GO:0007141//male meiosis I;GO:0007548//sex differentiation",GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
63948,99,0,0,0,0,0,18,0,0,0,0,0,"DMRTB1;DMRT-like family B with proline-rich C-terminal, 1",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
63950,0,0,0,0,0,0,0,0,9,0,7,0,DMRTA2;DMRT-like family A2,GO:0005634//nucleus,"GO:0035914//skeletal muscle cell differentiation;GO:0021796//cerebral cortex regionalization;GO:0048665//neuron fate specification;GO:0071542//dopaminergic neuron differentiation;GO:0002052//positive regulation of neuroblast proliferation;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding,-
63951,0,0,0,3,0,22,0,0,60,0,0,0,DMRTA1;DMRT-like family A1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0001541//ovarian follicle development;GO:0060179//male mating behavior;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,-
6396,0,2,0,15,13,0,0,74,10,0,0,0,SEC13;SEC13 homolog (S. cerevisiae),GO:0005635//nuclear envelope;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0000776//kinetochore;GO:0000139//Golgi membrane;GO:0031080//nuclear pore outer ring,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0000278//mitotic cell cycle;GO:0043687//post-translational protein modification;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051028//mRNA transport;GO:0048208//COPII vesicle coating;GO:0006886//intracellular protein transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006888//ER to Golgi vesicle-mediated transport,GO:0005515//protein binding,K14004//RNA transport;Protein processing in endoplasmic reticulum
63967,0,0,0,0,0,0,21,0,73,84,27,0,CLSPN;claspin,GO:0005654//nucleoplasm,GO:0006915//apoptotic process;GO:0032147//activation of protein kinase activity;GO:0006260//DNA replication;GO:0000077//DNA damage checkpoint;GO:0033314//mitotic DNA replication checkpoint;GO:0018105//peptidyl-serine phosphorylation;GO:0006281//DNA repair;GO:0031572//G2 DNA damage checkpoint;GO:0006921//cellular component disassembly involved in execution phase of apoptosis,GO:0010997//anaphase-promoting complex binding;GO:0003677//DNA binding;GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
6397,0,11,0,3,69,7,37,0,0,0,1,0,SEC14L1;SEC14-like 1 (S. cerevisiae),GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0006810//transport,-,K03006//Purine metabolism;Epstein-Barr virus infection;RNA polymerase;Pyrimidine metabolism;Huntington's disease;Metabolic pathways;Herpes simplex infection
63970,0,0,0,0,0,0,0,85,8,0,0,1,TP53AIP1;tumor protein p53 regulated apoptosis inducing protein 1,GO:0005739//mitochondrion,GO:0006915//apoptotic process,-,K13773//p53 signaling pathway
63971,0,114,1,21,170,37,35,48,60,0,11,0,KIF13A;kinesin family member 13A,GO:0032588//trans-Golgi network membrane;GO:0030496//midbody;GO:0000139//Golgi membrane;GO:0005871//kinesin complex;GO:0010008//endosome membrane;GO:0005813//centrosome;GO:0005874//microtubule,GO:0006200//ATP catabolic process;GO:0006886//intracellular protein transport;GO:0035459//cargo loading into vesicle;GO:0000910//cytokinesis;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0007018//microtubule-based movement;GO:0043001//Golgi to plasma membrane protein transport;GO:0008152//metabolic process;GO:0032438//melanosome organization;GO:0008333//endosome to lysosome transport,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity,-
63973,0,0,0,0,0,0,0,0,7,0,0,0,NEUROG2;neurogenin 2,GO:0005634//nucleus,"GO:0045666//positive regulation of neuron differentiation;GO:0021954//central nervous system neuron development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048469//cell maturation;GO:0045165//cell fate commitment;GO:0030900//forebrain development;GO:0007411//axon guidance;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0001764//neuron migration;GO:0006351//transcription, DNA-templated",GO:0046983//protein dimerization activity;GO:0043565//sequence-specific DNA binding;GO:0070888//E-box binding,-
63974,79,0,0,0,0,0,0,0,0,0,0,0,NEUROD6;neuronal differentiation 6,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0021542//dentate gyrus development;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
63976,70,0,0,0,0,0,11,93,35,0,0,0,PRDM16;PR domain containing 16,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex,"GO:0060021//palate development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050873//brown fat cell differentiation;GO:0043457//regulation of cellular respiration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0050872//white fat cell differentiation;GO:0035019//somatic stem cell maintenance;GO:0043586//tongue development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0022008//neurogenesis;GO:0030853//negative regulation of granulocyte differentiation",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0046332//SMAD binding,K04462//Chronic myeloid leukemia;Pathways in cancer;MAPK signaling pathway
63977,93,0,0,0,0,45,54,1,48,1,1,0,PRDM15;PR domain containing 15,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0032259//methylation;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity,-
63978,0,0,0,0,0,0,15,0,5,0,8,6,PRDM14;PR domain containing 14,GO:0005634//nucleus,"GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0000902//cell morphogenesis;GO:0006351//transcription, DNA-templated;GO:0044030//regulation of DNA methylation;GO:0030718//germ-line stem cell maintenance;GO:0048873//homeostasis of number of cells within a tissue;GO:0040029//regulation of gene expression, epigenetic;GO:0009566//fertilization;GO:0001708//cell fate specification;GO:0007281//germ cell development;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008168//methyltransferase activity,K12463//Neurotrophin signaling pathway
63979,62,0,0,0,28,16,0,0,14,0,6,0,FIGNL1;fidgetin-like 1,GO:0000228//nuclear chromosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0001649//osteoblast differentiation;GO:0071479//cellular response to ionizing radiation;GO:0033687//osteoblast proliferation;GO:0010569//regulation of double-strand break repair via homologous recombination;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0051726//regulation of cell cycle;GO:0043066//negative regulation of apoptotic process;GO:0046034//ATP metabolic process,GO:0005524//ATP binding;GO:0016787//hydrolase activity;GO:0000287//magnesium ion binding;GO:0005515//protein binding,-
63982,137,0,0,0,0,37,18,0,71,180,0,0,ANO3;anoctamin 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,GO:0017128//phospholipid scramblase activity;GO:0005229//intracellular calcium activated chloride channel activity,-
6399,0,0,0,31,128,0,17,0,21,0,36,0,TRAPPC2;trafficking protein particle complex 2,GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0001501//skeletal system development;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006355//regulation of transcription, DNA-templated",GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0044325//ion channel binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
640,0,0,0,0,0,0,0,0,28,0,10,0,"BLK;BLK proto-oncogene, Src family tyrosine kinase",GO:0005886//plasma membrane,GO:0035556//intracellular signal transduction;GO:0050853//B cell receptor signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0032024//positive regulation of insulin secretion,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding,-
6400,0,0,1,0,5,43,15,0,51,0,0,0,SEL1L;sel-1 suppressor of lin-12-like (C. elegans),GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007219//Notch signaling pathway;GO:0034976//response to endoplasmic reticulum stress,GO:0005515//protein binding,K14026//Protein processing in endoplasmic reticulum
64005,90,0,0,0,5,0,0,66,16,0,0,276,MYO1G;myosin IG,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016459//myosin complex,GO:0008152//metabolic process,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0003774//motor activity,-
6401,42,0,0,0,0,14,0,0,46,0,0,0,SELE;selectin E,GO:0005615//extracellular space;GO:0030863//cortical cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005901//caveola;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005905//coated pit,GO:0034612//response to tumor necrosis factor;GO:0007596//blood coagulation;GO:0030029//actin filament-based process;GO:0002092//positive regulation of receptor internalization;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0019722//calcium-mediated signaling;GO:0070555//response to interleukin-1;GO:0006954//inflammatory response;GO:0002523//leukocyte migration involved in inflammatory response;GO:0050900//leukocyte migration;GO:0032496//response to lipopolysaccharide;GO:0050727//regulation of inflammatory response;GO:0007202//activation of phospholipase C activity;GO:0050901//leukocyte tethering or rolling;GO:0002687//positive regulation of leukocyte migration;GO:0007159//leukocyte cell-cell adhesion,GO:0033691//sialic acid binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0070492//oligosaccharide binding;GO:0043274//phospholipase binding,K06494//African trypanosomiasis;Malaria;Cell adhesion molecules (CAMs)
6402,0,0,0,0,0,0,0,0,24,0,0,0,SELL;selectin L,GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0007596//blood coagulation;GO:0050900//leukocyte migration;GO:0033198//response to ATP;GO:0007155//cell adhesion,GO:0050839//cell adhesion molecule binding;GO:0043208//glycosphingolipid binding;GO:0008201//heparin binding;GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0002020//protease binding,K06495//Cell adhesion molecules (CAMs)
6403,78,0,0,0,0,0,0,4,24,0,7,0,"SELP;selectin P (granule membrane protein 140kDa, antigen CD62)",GO:0031088//platelet dense granule membrane;GO:0031092//platelet alpha granule membrane;GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005730//nucleolus;GO:0005615//extracellular space,GO:0007596//blood coagulation;GO:0032496//response to lipopolysaccharide;GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0002576//platelet degranulation;GO:0033623//regulation of integrin activation;GO:0010572//positive regulation of platelet activation;GO:0050901//leukocyte tethering or rolling;GO:0006954//inflammatory response;GO:0030168//platelet activation;GO:0050900//leukocyte migration;GO:0050829//defense response to Gram-negative bacterium;GO:0007159//leukocyte cell-cell adhesion;GO:0002687//positive regulation of leukocyte migration,GO:0048306//calcium-dependent protein binding;GO:0005515//protein binding;GO:0001530//lipopolysaccharide binding;GO:0008201//heparin binding;GO:0043208//glycosphingolipid binding;GO:0033691//sialic acid binding;GO:0070492//oligosaccharide binding;GO:0042806//fucose binding;GO:0001948//glycoprotein binding,K06496//Malaria;Cell adhesion molecules (CAMs);Staphylococcus aureus infection
6404,0,0,0,11,0,9,26,0,17,0,3,0,SELPLG;selectin P ligand,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007155//cell adhesion;GO:0050902//leukocyte adhesive activation;GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0071354//cellular response to interleukin-6;GO:0050901//leukocyte tethering or rolling,GO:0005102//receptor binding;GO:0005515//protein binding,K06544//Cell adhesion molecules (CAMs);Staphylococcus aureus infection
6405,74,0,0,0,3,0,54,15,50,0,0,0,"SEMA3F;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F",GO:0016020//membrane;GO:0005615//extracellular space,GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0021785//branchiomotor neuron axon guidance;GO:0061549//sympathetic ganglion development;GO:0097491//sympathetic neuron projection guidance;GO:0021675//nerve development;GO:0050919//negative chemotaxis;GO:0001755//neural crest cell migration;GO:0007411//axon guidance;GO:0048846//axon extension involved in axon guidance;GO:0097490//sympathetic neuron projection extension;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0021612//facial nerve structural organization,GO:0045499//chemorepellent activity;GO:0004872//receptor activity,K06840//Axon guidance
6406,0,270,0,13,7,0,0,0,2,0,0,0,SEMG1;semenogelin I,GO:0005634//nucleus;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0007320//insemination,GO:0005515//protein binding;GO:0005198//structural molecule activity,K06672//Cell cycle - yeast
64061,0,0,0,0,16,0,22,0,23,0,0,0,TSPYL2;TSPY-like 2,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0016568//chromatin modification;GO:0007049//cell cycle;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006355//regulation of transcription, DNA-templated;GO:0008156//negative regulation of DNA replication;GO:0045859//regulation of protein kinase activity;GO:0045786//negative regulation of cell cycle;GO:0006334//nucleosome assembly;GO:0030308//negative regulation of cell growth;GO:0044267//cellular protein metabolic process;GO:0006351//transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0009966//regulation of signal transduction",GO:0000182//rDNA binding,-
64062,0,1,0,13,89,22,18,0,29,276,1,0,RBM26;RNA binding motif protein 26,-,GO:0006397//mRNA processing;GO:0010923//negative regulation of phosphatase activity,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
64063,0,1,1,0,0,0,0,0,26,0,1,0,"PRSS22;protease, serine, 22",GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
64065,0,0,0,24,89,15,43,0,80,0,5,0,"PERP;PERP, TP53 apoptosis effector",GO:0005887//integral component of plasma membrane;GO:0005794//Golgi apparatus;GO:0030057//desmosome;GO:0005739//mitochondrion,GO:0097186//amelogenesis;GO:0045862//positive regulation of proteolysis;GO:0034113//heterotypic cell-cell adhesion;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0002934//desmosome organization;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator,-,K10136//p53 signaling pathway
64066,0,0,0,0,0,0,0,0,6,0,0,0,MMP27;matrix metallopeptidase 27,GO:0005578//proteinaceous extracellular matrix,GO:0030574//collagen catabolic process;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
64067,0,0,0,0,0,13,73,0,34,0,0,0,NPAS3;neuronal PAS domain protein 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0001964//startle response;GO:0007165//signal transduction;GO:0007626//locomotory behavior;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042711//maternal behavior",GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0004871//signal transducer activity,-
6407,101,54,0,0,0,0,0,0,11,0,0,0,SEMG2;semenogelin II,GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0019953//sexual reproduction,GO:0005198//structural molecule activity,K00907//Gastric acid secretion;Calcium signaling pathway;Focal adhesion;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
64072,330,0,0,0,9,96,32,0,193,30,8,0,CDH23;cadherin-related 23,GO:0032420//stereocilium;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007605//sensory perception of sound;GO:0050957//equilibrioception;GO:0050896//response to stimulus;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007601//visual perception;GO:0045494//photoreceptor cell maintenance;GO:0051480//cytosolic calcium ion homeostasis;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0006816//calcium ion transport;GO:0050953//sensory perception of light stimulus,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
64073,0,0,0,17,3,0,0,137,0,0,15,0,C19orf33;chromosome 19 open reading frame 33,GO:0005634//nucleus,-,GO:0003690//double-stranded DNA binding;GO:0003697//single-stranded DNA binding,-
64077,0,0,0,0,0,0,0,82,0,0,0,0,LHPP;phospholysine phosphohistidine inorganic pyrophosphate phosphatase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0006796//phosphate-containing compound metabolic process;GO:0006470//protein dephosphorylation,GO:0042803//protein homodimerization activity;GO:0004427//inorganic diphosphatase activity;GO:0008969//phosphohistidine phosphatase activity;GO:0000287//magnesium ion binding,K11725//Oxidative phosphorylation
64078,0,0,0,0,0,0,60,0,21,0,5,0,"SLC28A3;solute carrier family 28 (concentrative nucleoside transporter), member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0015860//purine nucleoside transmembrane transport;GO:0072531//pyrimidine-containing compound transmembrane transport;GO:0055085//transmembrane transport;GO:0006863//purine nucleobase transport;GO:0015864//pyrimidine nucleoside transport;GO:0015855//pyrimidine nucleobase transport,GO:0001882//nucleoside binding;GO:0015389//pyrimidine- and adenine-specific:sodium symporter activity;GO:0015390//purine-specific nucleoside:sodium symporter activity,-
64080,0,0,0,0,0,23,10,0,28,0,0,0,RBKS;ribokinase,GO:0070062//extracellular vesicular exosome,GO:0046835//carbohydrate phosphorylation;GO:0019303//D-ribose catabolic process,GO:0005524//ATP binding;GO:0004747//ribokinase activity,K00852//Pentose phosphate pathway
64081,0,0,39,0,13,0,12,81,44,9,5,0,PBLD;phenazine biosynthesis-like protein domain containing,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0009058//biosynthetic process;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0030277//maintenance of gastrointestinal epithelium;GO:0010633//negative regulation of epithelial cell migration;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0060392//negative regulation of SMAD protein import into nucleus,GO:0016853//isomerase activity;GO:0005515//protein binding,-
64083,0,25,2,56,263,5,0,394,18,0,55,1,GOLPH3;golgi phosphoprotein 3 (coat-protein),GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0032580//Golgi cisterna membrane;GO:0031985//Golgi cisterna;GO:0005768//endosome;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network,GO:0008283//cell proliferation;GO:0010467//gene expression;GO:0030032//lamellipodium assembly;GO:0007030//Golgi organization;GO:0048194//Golgi vesicle budding;GO:0009306//protein secretion;GO:0050714//positive regulation of protein secretion;GO:0010821//regulation of mitochondrion organization;GO:0009101//glycoprotein biosynthetic process;GO:0050901//leukocyte tethering or rolling;GO:0016477//cell migration;GO:0043001//Golgi to plasma membrane protein transport;GO:0045053//protein retention in Golgi apparatus;GO:0032008//positive regulation of TOR signaling;GO:0060352//cell adhesion molecule production,GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0005515//protein binding;GO:0019899//enzyme binding,K15620//Transcriptional misregulation in cancer
64084,0,0,0,0,0,6,0,0,59,0,0,0,CLSTN2;calsyntenin 2,GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
64087,0,136,5,196,494,44,0,0,23,0,1,0,MCCC2;methylcrotonoyl-CoA carboxylase 2 (beta),GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006552//leucine catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0015936//coenzyme A metabolic process;GO:0006766//vitamin metabolic process;GO:0006768//biotin metabolic process;GO:0009083//branched-chain amino acid catabolic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004485//methylcrotonoyl-CoA carboxylase activity,"K01969//Valine, leucine and isoleucine degradation;Metabolic pathways"
64089,0,0,0,0,1,11,32,0,16,0,9,0,SNX16;sorting nexin 16,GO:0005770//late endosome;GO:0031901//early endosome membrane;GO:0031313//extrinsic component of endosome membrane;GO:0005769//early endosome;GO:0005764//lysosome;GO:0031902//late endosome membrane,GO:0045022//early endosome to late endosome transport;GO:0008333//endosome to lysosome transport;GO:0006622//protein targeting to lysosome,GO:0042802//identical protein binding;GO:0035091//phosphatidylinositol binding,-
64090,22,0,0,0,0,0,0,0,10,0,0,0,GAL3ST2;galactose-3-O-sulfotransferase 2,GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0009058//biosynthetic process,GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity,-
64091,0,0,0,0,0,0,0,0,19,0,18,0,POPDC2;popeye domain containing 2,GO:0016021//integral component of membrane,GO:0060931//sinoatrial node cell development;GO:0002027//regulation of heart rate;GO:0042391//regulation of membrane potential,GO:0030552//cAMP binding,-
64092,0,0,0,0,0,0,0,0,16,0,6,0,"SAMSN1;SAM domain, SH3 domain and nuclear localization signals 1",GO:0005634//nucleus;GO:0005829//cytosol;GO:0001726//ruffle,GO:0050869//negative regulation of B cell activation;GO:0002820//negative regulation of adaptive immune response;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation,GO:0001784//phosphotyrosine binding;GO:0044822//poly(A) RNA binding,-
64093,0,0,0,0,0,0,6,0,18,0,2,0,SMOC1;SPARC related modular calcium binding 1,GO:0005604//basement membrane,GO:0030154//cell differentiation;GO:0001654//eye development;GO:0030198//extracellular matrix organization;GO:0060173//limb development;GO:0045667//regulation of osteoblast differentiation;GO:0010811//positive regulation of cell-substrate adhesion;GO:0007165//signal transduction,GO:0050840//extracellular matrix binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
64094,0,0,0,0,0,17,22,0,41,0,0,0,SMOC2;SPARC related modular calcium binding 2,GO:0005614//interstitial matrix;GO:0005604//basement membrane,GO:0007165//signal transduction;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization,GO:0008201//heparin binding;GO:0005509//calcium ion binding,K10809//Autoimmune thyroid disease
64096,0,0,0,0,0,0,1,0,24,0,0,0,GFRA4;GDNF family receptor alpha 4,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0031225//anchored component of membrane,GO:0035860//glial cell-derived neurotrophic factor receptor signaling pathway;GO:0030279//negative regulation of ossification,GO:0016167//glial cell-derived neurotrophic factor receptor activity,-
64097,0,50,0,87,100,0,44,61,12,0,21,0,EPB41L4A;erythrocyte membrane protein band 4.1 like 4A,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0019898//extrinsic component of membrane,-,GO:0008092//cytoskeletal protein binding,-
64098,0,0,0,0,0,15,2,0,0,0,0,0,"PARVG;parvin, gamma",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005925//focal adhesion,GO:0031532//actin cytoskeleton reorganization;GO:0007160//cell-matrix adhesion,GO:0003779//actin binding,K06275//Focal adhesion
641,0,0,0,0,0,22,82,0,25,0,4,0,"BLM;Bloom syndrome, RecQ helicase-like","GO:0000781//chromosome, telomeric region;GO:0000228//nuclear chromosome;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus;GO:0045120//pronucleus;GO:0016363//nuclear matrix;GO:0000800//lateral element;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0016605//PML body","GO:0051782//negative regulation of cell division;GO:0000733//DNA strand renaturation;GO:0006974//cellular response to DNA damage stimulus;GO:0000729//DNA double-strand break processing;GO:0045910//negative regulation of DNA recombination;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0051098//regulation of binding;GO:0006310//DNA recombination;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0010165//response to X-ray;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0072711//cellular response to hydroxyurea;GO:0000724//double-strand break repair via homologous recombination;GO:0046632//alpha-beta T cell differentiation;GO:0051259//protein oligomerization;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0072757//cellular response to camptothecin;GO:0045950//negative regulation of mitotic recombination;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071479//cellular response to ionizing radiation;GO:0031297//replication fork processing;GO:0000723//telomere maintenance;GO:0032508//DNA duplex unwinding;GO:0048478//replication fork protection",GO:0005515//protein binding;GO:0036310//annealing helicase activity;GO:0008026//ATP-dependent helicase activity;GO:0000405//bubble DNA binding;GO:0051880//G-quadruplex DNA binding;GO:0003697//single-stranded DNA binding;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0004386//helicase activity;GO:0016887//ATPase activity;GO:0002039//p53 binding;GO:0009378//four-way junction helicase activity;GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding,K10901//Homologous recombination;Fanconi anemia pathway
64100,3,0,0,0,0,1,23,1,15,0,0,0,ELSPBP1;epididymal sperm binding protein 1,GO:0005576//extracellular region,GO:0007338//single fertilization,-,K01403//Pathways in cancer;Transcriptional misregulation in cancer;Bladder cancer;Leukocyte transendothelial migration
64101,0,0,0,0,0,24,8,38,5,0,0,333,LRRC4;leucine rich repeat containing 4,GO:0043197//dendritic spine;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane;GO:0060076//excitatory synapse;GO:0030054//cell junction,GO:0050807//regulation of synapse organization;GO:0050808//synapse organization;GO:0097119//postsynaptic density protein 95 clustering,GO:0005515//protein binding,K07523//Axon guidance
64102,0,0,0,0,0,0,0,0,34,0,0,0,TNMD;tenomodulin,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005635//nuclear envelope,GO:0035990//tendon cell differentiation;GO:0016525//negative regulation of angiogenesis;GO:0071773//cellular response to BMP stimulus;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001886//endothelial cell morphogenesis,-,K01099//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
64105,0,0,0,0,0,0,0,0,44,0,5,0,CENPK;centromere protein K,GO:0005654//nucleoplasm;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol,GO:0034080//CENP-A containing nucleosome assembly;GO:0000278//mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006334//nucleosome assembly,-,-
64106,0,0,0,0,0,0,0,0,4,0,0,0,NPFFR1;neuropeptide FF receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity;GO:0004930//G-protein coupled receptor activity,K04240//Neuroactive ligand-receptor interaction
64108,0,0,0,0,0,32,0,0,9,0,0,0,RTP4;receptor (chemosensory) transporter protein 4,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0006612//protein targeting to membrane;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0005515//protein binding,-
64109,0,0,0,0,0,0,15,42,0,0,0,0,CRLF2;cytokine receptor-like factor 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0035745//T-helper 2 cell cytokine production;GO:0002380//immunoglobulin secretion involved in immune response;GO:0006954//inflammatory response,-,K05078//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
64110,0,38,0,0,72,0,0,0,24,0,0,0,"MAGEF1;melanoma antigen family F, 1",GO:0070062//extracellular vesicular exosome,-,-,K12464//Neurotrophin signaling pathway
64112,0,58,0,14,50,0,4,0,0,0,4,0,MOAP1;modulator of apoptosis 1,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005741//mitochondrial outer membrane;GO:0005737//cytoplasm,GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0001844//protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction;K11447//Transcriptional misregulation in cancer
64114,0,1,0,10,70,0,28,27,12,0,3,0,TMBIM1;transmembrane BAX inhibitor motif containing 1,GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,GO:1902045//negative regulation of Fas signaling pathway;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:2000504//positive regulation of blood vessel remodeling;GO:0048553//negative regulation of metalloenzyme activity,GO:0005123//death receptor binding,-
64115,0,0,0,0,0,10,4,57,48,0,20,0,C10orf54;chromosome 10 open reading frame 54,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,"GO:0002725//negative regulation of T cell cytokine production;GO:0048863//stem cell differentiation;GO:2000562//negative regulation of CD4-positive, alpha-beta T cell proliferation;GO:2000738//positive regulation of stem cell differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0030509//BMP signaling pathway",-,-
64116,91,0,0,0,0,35,15,0,17,0,0,83,"SLC39A8;solute carrier family 39 (zinc transporter), member 8",GO:0031090//organelle membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006829//zinc ion transport;GO:0055085//transmembrane transport,GO:0046873//metal ion transmembrane transporter activity,-
64118,99,3,0,10,7,25,0,110,0,0,23,0,DUS1L;dihydrouridine synthase 1-like (S. cerevisiae),-,GO:0055114//oxidation-reduction process;GO:0002943//tRNA dihydrouridine synthesis,GO:0050660//flavin adenine dinucleotide binding;GO:0017150//tRNA dihydrouridine synthase activity,-
64121,0,29,0,14,36,12,0,0,30,0,6,0,RRAGC;Ras-related GTP binding C,GO:0005764//lysosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle,"GO:0016049//cell growth;GO:0071230//cellular response to amino acid stimulus;GO:0007264//small GTPase mediated signal transduction;GO:0008380//RNA splicing;GO:0034613//cellular protein localization;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0006184//GTP catabolic process",GO:0019003//GDP binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0000287//magnesium ion binding,-
64122,0,0,28,0,4,0,0,0,11,0,0,0,FN3K;fructosamine 3 kinase,-,GO:0030855//epithelial cell differentiation;GO:0016310//phosphorylation;GO:0030393//fructoselysine metabolic process,GO:0030387//fructosamine-3-kinase activity,-
64123,0,0,0,0,0,11,12,0,45,0,1,0,"ELTD1;EGF, latrophilin and seven transmembrane domain containing 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0005509//calcium ion binding,-
64127,0,0,1,0,0,14,0,0,20,0,1,224,NOD2;nucleotide-binding oligomerization domain containing 2,GO:0008180//COP9 signalosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043234//protein complex,"GO:0032755//positive regulation of interleukin-6 production;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071608//macrophage inflammatory protein-1 alpha production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0007584//response to nutrient;GO:0006965//positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0044130//negative regulation of growth of symbiont in host;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002224//toll-like receptor signaling pathway;GO:0032733//positive regulation of interleukin-10 production;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000187//activation of MAPK activity;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0035419//activation of MAPK activity involved in innate immune response;GO:0002381//immunoglobulin production involved in immunoglobulin mediated immune response;GO:0002282//microglial cell activation involved in immune response;GO:0031398//positive regulation of protein ubiquitination;GO:0002925//positive regulation of humoral immune response mediated by circulating immunoglobulin;GO:0032735//positive regulation of interleukin-12 production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0046645//positive regulation of gamma-delta T cell activation;GO:0051259//protein oligomerization;GO:0032703//negative regulation of interleukin-2 production;GO:0045087//innate immune response;GO:0006952//defense response;GO:0032689//negative regulation of interferon-gamma production;GO:0007254//JNK cascade;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0030277//maintenance of gastrointestinal epithelium;GO:0050679//positive regulation of epithelial cell proliferation;GO:0032695//negative regulation of interleukin-12 production;GO:0046330//positive regulation of JNK cascade;GO:0034146//toll-like receptor 5 signaling pathway;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0032740//positive regulation of interleukin-17 production;GO:0002367//cytokine production involved in immune response;GO:0002862//negative regulation of inflammatory response to antigenic stimulus;GO:0071225//cellular response to muramyl dipeptide;GO:0060585//positive regulation of prostaglandin-endoperoxide synthase activity;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0045747//positive regulation of Notch signaling pathway;GO:0032498//detection of muramyl dipeptide;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0032731//positive regulation of interleukin-1 beta production;GO:0032496//response to lipopolysaccharide;GO:0050727//regulation of inflammatory response;GO:0009595//detection of biotic stimulus;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0090022//regulation of neutrophil chemotaxis;GO:0071224//cellular response to peptidoglycan;GO:0050830//defense response to Gram-positive bacterium;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:2000363//positive regulation of prostaglandin-E synthase activity;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0050766//positive regulation of phagocytosis;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032495//response to muramyl dipeptide;GO:0034162//toll-like receptor 9 signaling pathway;GO:0002830//positive regulation of type 2 immune response;GO:0002710//negative regulation of T cell mediated immunity;GO:0032701//negative regulation of interleukin-18 production;GO:2000110//negative regulation of macrophage apoptotic process;GO:0002732//positive regulation of dendritic cell cytokine production;GO:0002227//innate immune response in mucosa;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0050871//positive regulation of B cell activation;GO:0034138//toll-like receptor 3 signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016045//detection of bacterium;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0043330//response to exogenous dsRNA;GO:0051353//positive regulation of oxidoreductase activity;GO:0035556//intracellular signal transduction;GO:0042742//defense response to bacterium;GO:0034142//toll-like receptor 4 signaling pathway",GO:0032500//muramyl dipeptide binding;GO:0042834//peptidoglycan binding;GO:0005515//protein binding;GO:0050700//CARD domain binding;GO:0019901//protein kinase binding;GO:0005524//ATP binding;GO:0019899//enzyme binding,K10165//NOD-like receptor signaling pathway;Shigellosis;Tuberculosis
64129,1,0,0,0,0,29,0,0,45,0,9,1,TINAGL1;tubulointerstitial nephritis antigen-like 1,GO:0005737//cytoplasm;GO:0031012//extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0006508//proteolysis;GO:0016197//endosomal transport;GO:0006898//receptor-mediated endocytosis;GO:0006955//immune response,GO:0005201//extracellular matrix structural constituent;GO:0008234//cysteine-type peptidase activity;GO:0030247//polysaccharide binding;GO:0043236//laminin binding;GO:0005044//scavenger receptor activity,K01363//Lysosome;Antigen processing and presentation
641298,3,0,0,0,0,2,2,0,29,0,10,0,SMG1P1;SMG1 pseudogene 1,-,-,-,K08873//mRNA surveillance pathway
64131,0,0,0,0,0,31,0,4,57,0,0,0,XYLT1;xylosyltransferase I,GO:0005789//endoplasmic reticulum membrane;GO:0005576//extracellular region;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0030206//chondroitin sulfate biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0034605//cellular response to heat;GO:0006024//glycosaminoglycan biosynthetic process,GO:0030158//protein xylosyltransferase activity;GO:0008375//acetylglucosaminyltransferase activity,K00771//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
641311,0,0,0,0,0,0,30,0,0,0,0,0,RPL31P11;ribosomal protein L31 pseudogene 11,-,-,-,K02910//Ribosome
64132,0,0,0,0,0,2,1,33,4,136,0,0,XYLT2;xylosyltransferase II,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030210//heparin biosynthetic process;GO:0006024//glycosaminoglycan biosynthetic process,GO:0008375//acetylglucosaminyltransferase activity;GO:0030158//protein xylosyltransferase activity,K00771//Glycosaminoglycan biosynthesis - heparan sulfate;Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways
641339,0,0,0,15,0,0,2,0,21,0,26,0,ZNF674;zinc finger protein 674,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
64135,0,32,1,38,119,46,0,0,5,0,0,0,IFIH1;interferon induced with helicase C domain 1,GO:0005634//nucleus;GO:0005829//cytosol,GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0032727//positive regulation of interferon-alpha production;GO:0034344//regulation of type III interferon production;GO:0032728//positive regulation of interferon-beta production;GO:0032480//negative regulation of type I interferon production;GO:0009597//detection of virus;GO:0016925//protein sumoylation;GO:0039528//cytoplasmic pattern recognition receptor signaling pathway in response to virus;GO:0009615//response to virus,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0043021//ribonucleoprotein complex binding;GO:0003677//DNA binding;GO:0003727//single-stranded RNA binding;GO:0003725//double-stranded RNA binding;GO:0004386//helicase activity;GO:0005524//ATP binding,K12647//Herpes simplex infection;RIG-I-like receptor signaling pathway;Influenza A;Measles
641367,0,0,1,0,0,0,26,0,0,0,0,0,LOC641367;cyclin Y-like 1 pseudogene,-,-,-,-
64137,0,0,0,0,0,9,0,50,47,269,0,0,"ABCG4;ATP-binding cassette, sub-family G (WHITE), member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0033344//cholesterol efflux;GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0017127//cholesterol transporter activity;GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K05680//ABC transporters
641371,0,0,0,0,1,0,0,0,0,0,0,0,ACOT1;acyl-CoA thioesterase 1,GO:0005829//cytosol,GO:0001676//long-chain fatty acid metabolic process;GO:0006637//acyl-CoA metabolic process;GO:0000038//very long-chain fatty acid metabolic process,GO:0047617//acyl-CoA hydrolase activity;GO:0016290//palmitoyl-CoA hydrolase activity;GO:0052689//carboxylic ester hydrolase activity,K01068//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
641372,0,0,45,8,0,12,0,0,21,0,0,0,ACOT6;acyl-CoA thioesterase 6,GO:0005829//cytosol,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
6414,0,0,0,1,35,16,0,0,19,4,0,0,"SEPP1;selenoprotein P, plasma, 1",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0040007//growth;GO:0019953//sexual reproduction;GO:0007420//brain development;GO:0009791//post-embryonic development;GO:0006979//response to oxidative stress;GO:0001887//selenium compound metabolic process;GO:0007626//locomotory behavior,GO:0008430//selenium binding,-
64145,0,0,0,0,0,0,0,0,21,0,0,0,"ZFYVE20;zinc finger, FYVE domain containing 20",GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0005768//endosome,GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0007596//blood coagulation,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0017137//Rab GTPase binding,K12481//Endocytosis
641455,71,5,5,24,79,0,2,6,18,194,30,0,"POTEM;POTE ankyrin domain family, member M",-,-,-,K05692//Pathogenic Escherichia coli infection;Gastric acid secretion;Focal adhesion;Vibrio cholerae infection;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Dilated cardiomyopathy;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Phototransduction - fly;Adherens junction;Viral myocarditis;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Salmonella infection;Phagosome
64147,114,20,1,75,134,24,45,240,77,0,163,0,KIF9;kinesin family member 9,GO:0005871//kinesin complex;GO:0002102//podosome;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0031982//vesicle,GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:1903008//organelle disassembly;GO:0071801//regulation of podosome assembly;GO:0007596//blood coagulation;GO:0007018//microtubule-based movement;GO:0022617//extracellular matrix disassembly,GO:0008017//microtubule binding;GO:0005515//protein binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0046983//protein dimerization activity;GO:0005524//ATP binding,-
64149,0,0,1,16,29,15,56,0,37,0,0,229,C17orf75;chromosome 17 open reading frame 75,-,-,-,K11447//Transcriptional misregulation in cancer
6415,0,47,2,17,95,3,0,0,0,0,0,0,"SEPW1;selenoprotein W, 1",GO:0005737//cytoplasm,GO:0045454//cell redox homeostasis,GO:0016209//antioxidant activity;GO:0008430//selenium binding,-
64151,1,0,49,59,108,8,0,0,29,0,34,0,"NCAPG;non-SMC condensin I complex, subunit G",GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0016020//membrane;GO:0000796//condensin complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0000278//mitotic cell cycle;GO:0007076//mitotic chromosome condensation,GO:0005515//protein binding,K06678//Cell cycle - yeast
641515,0,0,0,0,13,0,20,0,0,0,6,0,"LOC641515;alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein pseudogene",-,-,-,K13748//Metabolic pathways;N-Glycan biosynthesis
641518,0,24,0,0,37,0,0,0,21,0,0,0,LEF1-AS1;LEF1 antisense RNA 1,-,-,-,K04492//Endometrial cancer;Wnt signaling pathway;Adherens junction;Colorectal cancer;Melanogenesis;Thyroid cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Acute myeloid leukemia;Basal cell carcinoma;Prostate cancer
6416,0,0,0,32,89,11,0,0,1,0,0,0,MAP2K4;mitogen-activated protein kinase kinase 4,GO:0005634//nucleus;GO:0005829//cytosol;GO:0043204//perikaryon;GO:0032839//dendrite cytoplasm,GO:0007257//activation of JUN kinase activity;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0045740//positive regulation of DNA replication;GO:0006915//apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0072709//cellular response to sorbitol;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0007165//signal transduction;GO:0002224//toll-like receptor signaling pathway;GO:0043525//positive regulation of neuron apoptotic process;GO:0034166//toll-like receptor 10 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0045087//innate immune response;GO:0034134//toll-like receptor 2 signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007254//JNK cascade,GO:0004713//protein tyrosine kinase activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0008545//JUN kinase kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity,K04430//Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;ErbB signaling pathway;MAPK signaling pathway;Influenza A;Toll-like receptor signaling pathway;Fc epsilon RI signaling pathway;HTLV-I infection;GnRH signaling pathway;Chagas disease (American trypanosomiasis)
641649,0,50,0,11,17,0,12,0,0,0,89,0,TMEM91;transmembrane protein 91,GO:0016021//integral component of membrane,GO:0009607//response to biotic stimulus;GO:0002244//hematopoietic progenitor cell differentiation,-,"K00166//Biosynthesis of secondary metabolites;Metabolic pathways;Valine, leucine and isoleucine degradation"
641654,0,0,0,16,9,0,0,0,5,0,0,0,"HEPN1;hepatocellular carcinoma, down-regulated 1",GO:0005737//cytoplasm,-,-,-
64167,115,0,0,16,0,18,0,33,95,33,1,0,ERAP2;endoplasmic reticulum aminopeptidase 2,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0008217//regulation of blood pressure;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0006508//proteolysis,GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
64168,76,31,1,131,37,0,16,0,43,0,69,322,NECAB1;N-terminal EF-hand calcium binding protein 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005509//calcium ion binding,-
64170,0,0,0,0,0,0,35,0,0,256,0,0,"CARD9;caspase recruitment domain family, member 9",GO:0005737//cytoplasm,"GO:0045076//regulation of interleukin-2 biosynthetic process;GO:0032495//response to muramyl dipeptide;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0050830//defense response to Gram-positive bacterium;GO:0051607//defense response to virus;GO:0032755//positive regulation of interleukin-6 production;GO:0042981//regulation of apoptotic process;GO:0009620//response to fungus;GO:0032494//response to peptidoglycan;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0043330//response to exogenous dsRNA;GO:0045408//regulation of interleukin-6 biosynthetic process;GO:0046330//positive regulation of JNK cascade;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042534//regulation of tumor necrosis factor biosynthetic process",GO:0050700//CARD domain binding;GO:0042803//protein homodimerization activity,K12794//NOD-like receptor signaling pathway;Tuberculosis
641700,0,0,0,0,0,0,1,0,0,0,0,0,ECSCR;endothelial cell surface expressed chemotaxis and apoptosis regulator,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0001525//angiogenesis;GO:0006915//apoptotic process;GO:0006935//chemotaxis;GO:0030154//cell differentiation,-,-
64172,0,0,0,0,0,10,0,0,6,0,30,0,OSGEPL1;O-sialoglycoprotein endopeptidase-like 1,GO:0005739//mitochondrion,GO:0070526//threonylcarbamoyladenosine biosynthetic process,"GO:0046872//metal ion binding;GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups",-
64174,0,0,0,0,0,0,0,0,6,0,0,0,DPEP2;dipeptidase 2,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0019369//arachidonic acid metabolic process;GO:0006508//proteolysis;GO:0044281//small molecule metabolic process;GO:0006691//leukotriene metabolic process,GO:0008235//metalloexopeptidase activity;GO:0008239//dipeptidyl-peptidase activity;GO:0016805//dipeptidase activity;GO:0046872//metal ion binding,-
64175,0,0,0,0,0,0,1,0,14,0,11,0,LEPRE1;leucine proline-enriched proteoglycan (leprecan) 1,GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0032991//macromolecular complex;GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus,GO:0030278//regulation of ossification;GO:0006457//protein folding;GO:0030199//collagen fibril organization;GO:0055114//oxidation-reduction process;GO:0060348//bone development;GO:0050821//protein stabilization;GO:0061077//chaperone-mediated protein folding;GO:0008285//negative regulation of cell proliferation;GO:0032963//collagen metabolic process;GO:1901874//negative regulation of post-translational protein modification;GO:0016049//cell growth;GO:0030198//extracellular matrix organization;GO:0019511//peptidyl-proline hydroxylation;GO:0050708//regulation of protein secretion,GO:0032403//protein complex binding;GO:0031418//L-ascorbic acid binding;GO:0005518//collagen binding;GO:0019797//procollagen-proline 3-dioxygenase activity;GO:0005506//iron ion binding,-
6418,50,165,21,107,431,23,0,0,23,0,7,0,SET;SET nuclear proto-oncogene,GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0043086//negative regulation of catalytic activity;GO:0010467//gene expression;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0035067//negative regulation of histone acetylation;GO:0006913//nucleocytoplasmic transport;GO:0043524//negative regulation of neuron apoptotic process;GO:0006337//nucleosome disassembly;GO:0006334//nucleosome assembly;GO:0050790//regulation of catalytic activity;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0004864//protein phosphatase inhibitor activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0008601//protein phosphatase type 2A regulator activity;GO:0003677//DNA binding,-
64180,0,0,0,0,0,0,0,0,45,177,11,0,DPEP3;dipeptidase 3,GO:0031225//anchored component of membrane,GO:0007140//male meiosis;GO:0006508//proteolysis,GO:0008239//dipeptidyl-peptidase activity;GO:0008235//metalloexopeptidase activity;GO:0046872//metal ion binding;GO:0016805//dipeptidase activity,-
64184,0,0,0,0,0,30,0,0,0,0,0,0,EDDM3B;epididymal protein 3B,GO:0005576//extracellular region,-,-,-
6419,0,0,1,8,13,0,0,1,5,0,11,0,SETMAR;SET domain and mariner transposase fusion gene,GO:0005694//chromosome;GO:0005634//nucleus,"GO:0006313//transposition, DNA-mediated;GO:0000729//DNA double-strand break processing;GO:0034968//histone lysine methylation;GO:2001034//positive regulation of double-strand break repair via nonhomologous end joining;GO:0000737//DNA catabolic process, endonucleolytic;GO:2001251//negative regulation of chromosome organization;GO:0071157//negative regulation of cell cycle arrest;GO:0015074//DNA integration",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004519//endonuclease activity;GO:0004803//transposase activity;GO:0008270//zinc ion binding;GO:0043566//structure-specific DNA binding;GO:0018024//histone-lysine N-methyltransferase activity,K11433//Lysine degradation
642,78,0,0,0,20,0,18,0,10,0,0,0,BLMH;bleomycin hydrolase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0009636//response to toxic substance;GO:0006508//proteolysis;GO:0042493//response to drug;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0000209//protein polyubiquitination,GO:0004177//aminopeptidase activity;GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0004180//carboxypeptidase activity,-
642006,3,0,0,0,0,0,0,29,0,0,0,0,"GUSBP10;glucuronidase, beta pseudogene 10",-,-,-,K01195//Drug metabolism - other enzymes;Lysosome;Starch and sucrose metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Glycosaminoglycan degradation;Porphyrin and chlorophyll metabolism
64207,0,1,0,7,14,0,0,10,11,171,30,0,IRF2BPL;interferon regulatory factor 2 binding protein-like,GO:0005634//nucleus;GO:0005615//extracellular space,GO:0046543//development of secondary female sexual characteristics;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0046872//metal ion binding,-
6421,0,46,49,21,133,0,0,13,43,0,25,0,SFPQ;splicing factor proline/glutamine-rich,GO:0000785//chromatin;GO:0042382//paraspeckles;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042752//regulation of circadian rhythm;GO:0000380//alternative mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0042754//negative regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0006310//DNA recombination;GO:0006281//DNA repair;GO:0070932//histone H3 deacetylation",GO:0001047//core promoter binding;GO:0044212//transcription regulatory region DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
64210,196,30,40,41,88,0,0,48,66,85,92,0,MMS19;MMS19 nucleotide excision repair homolog (S. cerevisiae),GO:0005819//spindle;GO:0071817//MMXD complex;GO:0005737//cytoplasm;GO:0005675//holo TFIIH complex;GO:0016020//membrane;GO:0097361//CIA complex;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006974//cellular response to DNA damage stimulus;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0006259//DNA metabolic process;GO:0044281//small molecule metabolic process;GO:0009725//response to hormone;GO:0006289//nucleotide-excision repair;GO:0006351//transcription, DNA-templated;GO:0016226//iron-sulfur cluster assembly;GO:0007059//chromosome segregation;GO:0000160//phosphorelay signal transduction system","GO:0003713//transcription coactivator activity;GO:0030159//receptor signaling complex scaffold activity;GO:0030331//estrogen receptor binding;GO:0005515//protein binding;GO:0030674//protein binding, bridging",-
64211,0,0,0,0,0,0,0,0,0,0,26,0,LHX5;LIM homeobox 5,GO:0005634//nucleus,"GO:0021937//cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation;GO:0021766//hippocampus development;GO:0021879//forebrain neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021527//spinal cord association neuron differentiation;GO:0021702//cerebellar Purkinje cell differentiation;GO:0021846//cell proliferation in forebrain;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding,-
64215,0,0,0,0,14,0,0,0,19,0,7,0,"DNAJC1;DnaJ (Hsp40) homolog, subfamily C, member 1",GO:0031965//nuclear membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0045861//negative regulation of proteolysis;GO:0006457//protein folding;GO:0032781//positive regulation of ATPase activity;GO:0050708//regulation of protein secretion;GO:0006417//regulation of translation,GO:0051087//chaperone binding;GO:0003682//chromatin binding;GO:0001671//ATPase activator activity;GO:0005515//protein binding;GO:0003677//DNA binding,K09521//Protein processing in endoplasmic reticulum
64216,0,1,0,11,1,0,30,48,38,0,5,0,"TFB2M;transcription factor B2, mitochondrial",GO:0042645//mitochondrial nucleoid;GO:0005759//mitochondrial matrix,"GO:0010467//gene expression;GO:0031167//rRNA methylation;GO:0006391//transcription initiation from mitochondrial promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006390//transcription from mitochondrial promoter","GO:0044822//poly(A) RNA binding;GO:0000179//rRNA (adenine-N6,N6-)-dimethyltransferase activity;GO:0003712//transcription cofactor activity",-
64218,0,1,0,0,19,8,0,0,15,19,11,0,"SEMA4A;sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0008360//regulation of cell shape;GO:0001525//angiogenesis;GO:0071526//semaphorin-plexin signaling pathway;GO:0007411//axon guidance;GO:0045063//T-helper 1 cell differentiation;GO:0010594//regulation of endothelial cell migration;GO:0016525//negative regulation of angiogenesis,GO:0005515//protein binding;GO:0004872//receptor activity,K06521//Axon guidance
64219,0,83,0,1,11,10,16,0,54,0,0,0,"PJA1;praja ring finger 1, E3 ubiquitin protein ligase",GO:0005737//cytoplasm,GO:0030163//protein catabolic process;GO:0016567//protein ubiquitination,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
6422,0,0,0,4,0,0,0,0,17,0,22,355,SFRP1;secreted frizzled-related protein 1,GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005622//intracellular;GO:0042995//cell projection;GO:0031012//extracellular matrix,"GO:0045578//negative regulation of B cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0001843//neural tube closure;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0035019//somatic stem cell maintenance;GO:0014070//response to organic cyclic compound;GO:0001649//osteoblast differentiation;GO:0014034//neural crest cell fate commitment;GO:0008584//male gonad development;GO:0090246//convergent extension involved in somitogenesis;GO:0033689//negative regulation of osteoblast proliferation;GO:0060346//bone trabecula formation;GO:0045671//negative regulation of osteoclast differentiation;GO:0044345//stromal-epithelial cell signaling involved in prostate gland development;GO:2000054//negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification;GO:2000041//negative regulation of planar cell polarity pathway involved in axis elongation;GO:0010629//negative regulation of gene expression;GO:0030336//negative regulation of cell migration;GO:0071380//cellular response to prostaglandin E stimulus;GO:0050679//positive regulation of epithelial cell proliferation;GO:2000080//negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation;GO:0030307//positive regulation of cell growth;GO:0008585//female gonad development;GO:0001954//positive regulation of cell-matrix adhesion;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0030178//negative regulation of Wnt signaling pathway;GO:0048546//digestive tract morphogenesis;GO:0051496//positive regulation of stress fiber assembly;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0010564//regulation of cell cycle process;GO:0043065//positive regulation of apoptotic process;GO:0030177//positive regulation of Wnt signaling pathway;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0071363//cellular response to growth factor stimulus;GO:0006508//proteolysis;GO:0071456//cellular response to hypoxia;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0042493//response to drug;GO:0030279//negative regulation of ossification;GO:0071305//cellular response to vitamin D;GO:0051894//positive regulation of focal adhesion assembly;GO:0071392//cellular response to estradiol stimulus;GO:0071356//cellular response to tumor necrosis factor;GO:0060218//hematopoietic stem cell differentiation;GO:0009267//cellular response to starvation;GO:0046676//negative regulation of insulin secretion;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0001944//vasculature development;GO:0008406//gonad development;GO:0022601//menstrual cycle phase;GO:0071347//cellular response to interleukin-1;GO:0060527//prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:2000052//positive regulation of non-canonical Wnt signaling pathway;GO:0007420//brain development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030308//negative regulation of cell growth;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0001657//ureteric bud development;GO:0030514//negative regulation of BMP signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0045765//regulation of angiogenesis;GO:0045880//positive regulation of smoothened signaling pathway;GO:0048147//negative regulation of fibroblast proliferation;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0009950//dorsal/ventral axis specification;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071391//cellular response to estrogen stimulus;GO:0071773//cellular response to BMP stimulus;GO:0002244//hematopoietic progenitor cell differentiation;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0071481//cellular response to X-ray;GO:0046851//negative regulation of bone remodeling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071504//cellular response to heparin;GO:0043508//negative regulation of JUN kinase activity;GO:0032855//positive regulation of Rac GTPase activity;GO:0060070//canonical Wnt signaling pathway",GO:0008201//heparin binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0042802//identical protein binding;GO:0017147//Wnt-protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0042813//Wnt-activated receptor activity;GO:0005109//frizzled binding;GO:0008144//drug binding,K02166//Wnt signaling pathway
64220,26,0,0,0,0,18,0,0,78,0,6,0,STRA6;stimulated by retinoic acid 6,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043234//protein complex,"GO:0061205//paramesonephric duct development;GO:0042573//retinoic acid metabolic process;GO:0030540//female genitalia development;GO:0048589//developmental growth;GO:0048844//artery morphogenesis;GO:0048520//positive regulation of behavior;GO:0060426//lung vasculature development;GO:0061156//pulmonary artery morphogenesis;GO:0050890//cognition;GO:0007631//feeding behavior;GO:0001568//blood vessel development;GO:0007507//heart development;GO:0001822//kidney development;GO:0060900//embryonic camera-type eye formation;GO:0061029//eyelid development in camera-type eye;GO:0071939//vitamin A import;GO:0003184//pulmonary valve morphogenesis;GO:0097070//ductus arteriosus closure;GO:0060323//head morphogenesis;GO:0003281//ventricular septum development;GO:0048546//digestive tract morphogenesis;GO:0048566//embryonic digestive tract development;GO:0050905//neuromuscular process;GO:0061143//alveolar primary septum development;GO:0030324//lung development;GO:0034633//retinol transport;GO:0048286//lung alveolus development;GO:0042297//vocal learning;GO:0001523//retinoid metabolic process;GO:0046427//positive regulation of JAK-STAT cascade;GO:0030325//adrenal gland development;GO:0061038//uterus morphogenesis;GO:0007612//learning;GO:0060539//diaphragm development;GO:0060325//face morphogenesis;GO:0043585//nose morphogenesis;GO:0048745//smooth muscle tissue development;GO:0043583//ear development;GO:0060322//head development;GO:0007603//phototransduction, visible light",GO:0004872//receptor activity;GO:0051183//vitamin transporter activity,-
64221,0,0,0,0,0,0,14,0,17,0,8,1,"ROBO3;roundabout, axon guidance receptor, homolog 3 (Drosophila)",GO:0030424//axon;GO:0016021//integral component of membrane,GO:0007411//axon guidance;GO:0016199//axon midline choice point recognition;GO:0001764//neuron migration,GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K06755//Axon guidance
64222,0,0,0,0,0,0,25,116,0,67,0,0,"TOR3A;torsin family 3, member A",GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen,GO:0006200//ATP catabolic process;GO:0051085//chaperone mediated protein folding requiring cofactor,GO:0016887//ATPase activity;GO:0005524//ATP binding,-
64223,0,0,0,8,1,0,0,0,24,0,0,0,"MLST8;MTOR associated protein, LST8 homolog (S. cerevisiae)",GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0031295//T cell costimulation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0030838//positive regulation of actin filament polymerization;GO:0045087//innate immune response;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0032314//regulation of Rac GTPase activity;GO:0032008//positive regulation of TOR signaling;GO:0008286//insulin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0032956//regulation of actin cytoskeleton organization;GO:0038095//Fc-epsilon receptor signaling pathway,GO:0005515//protein binding,K08266//mTOR signaling pathway
642236,0,0,0,0,0,31,22,0,13,0,0,0,LOC642236;FSHD region gene 1 pseudogene,-,-,-,-
64224,217,24,0,8,0,0,1,0,11,0,33,0,HERPUD2;HERPUD family member 2,GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0006986//response to unfolded protein,-,K14027//Protein processing in endoplasmic reticulum
64225,0,0,18,0,26,0,0,0,27,0,0,0,ATL2;atlastin GTPase 2,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0051260//protein homooligomerization;GO:0006184//GTP catabolic process;GO:0007029//endoplasmic reticulum organization;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0007030//Golgi organization,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
642273,0,0,0,0,0,0,0,49,23,0,0,0,"FAM110C;family with sequence similarity 110, member C",GO:0005634//nucleus;GO:0005938//cell cortex;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005815//microtubule organizing center,GO:0051897//positive regulation of protein kinase B signaling;GO:0030335//positive regulation of cell migration;GO:0060491//regulation of cell projection assembly,GO:0005515//protein binding;GO:0043014//alpha-tubulin binding,-
642280,0,0,0,0,0,19,0,0,18,0,0,0,"ZNF876P;zinc finger protein 876, pseudogene",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
6423,0,0,0,0,0,0,0,0,68,0,0,0,SFRP2;secreted frizzled-related protein 2,GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0042995//cell projection,"GO:0001569//patterning of blood vessels;GO:0045600//positive regulation of fat cell differentiation;GO:0001843//neural tube closure;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0003151//outflow tract morphogenesis;GO:0008584//male gonad development;GO:0031668//cellular response to extracellular stimulus;GO:0001944//vasculature development;GO:0002063//chondrocyte development;GO:0003214//cardiac left ventricle morphogenesis;GO:0008406//gonad development;GO:0060349//bone morphogenesis;GO:0010950//positive regulation of endopeptidase activity;GO:0036342//post-anal tail morphogenesis;GO:2000041//negative regulation of planar cell polarity pathway involved in axis elongation;GO:0008284//positive regulation of cell proliferation;GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010629//negative regulation of gene expression;GO:0030336//negative regulation of cell migration;GO:0030308//negative regulation of cell growth;GO:0007420//brain development;GO:0008285//negative regulation of cell proliferation;GO:0030199//collagen fibril organization;GO:0030307//positive regulation of cell growth;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060028//convergent extension involved in axis elongation;GO:0035413//positive regulation of catenin import into nucleus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0030178//negative regulation of Wnt signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030514//negative regulation of BMP signaling pathway;GO:2000035//regulation of stem cell division;GO:0048546//digestive tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0061056//sclerotome development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0071425//hematopoietic stem cell proliferation;GO:0007584//response to nutrient;GO:0061185//negative regulation of dermatome development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045669//positive regulation of osteoblast differentiation;GO:0042493//response to drug;GO:0045766//positive regulation of angiogenesis;GO:0071481//cellular response to X-ray;GO:0007267//cell-cell signaling;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043508//negative regulation of JUN kinase activity;GO:0042733//embryonic digit morphogenesis",GO:0042813//Wnt-activated receptor activity;GO:0010577//metalloenzyme activator activity;GO:0017147//Wnt-protein binding;GO:0048018//receptor agonist activity;GO:0061133//endopeptidase activator activity;GO:0030165//PDZ domain binding;GO:0005178//integrin binding;GO:0001968//fibronectin binding,K02176//Wnt signaling pathway
64231,0,0,0,0,0,0,0,0,32,0,0,0,"MS4A6A;membrane-spanning 4-domains, subfamily A, member 6A",GO:0016021//integral component of membrane,-,-,K08090//Asthma;Fc epsilon RI signaling pathway
64236,0,0,0,0,1,39,28,0,85,0,7,0,PDLIM2;PDZ and LIM domain 2 (mystique),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,-,GO:0051371//muscle alpha-actinin binding;GO:0032036//myosin heavy chain binding;GO:0031005//filamin binding;GO:0008270//zinc ion binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K05629//Tight junction;K05631//Tight junction;K05767//Adherens junction;Regulation of actin cytoskeleton;K11447//Transcriptional misregulation in cancer
642361,0,3,58,13,46,0,0,0,0,0,53,0,LOC642361;uncharacterized LOC642361,-,-,-,-
642394,0,0,0,0,0,0,0,0,0,0,1,0,ADARB2-AS1;ADARB2 antisense RNA 1,-,-,-,-
6424,0,0,0,0,0,0,44,0,0,0,0,515,SFRP4;secreted frizzled-related protein 4,GO:0032589//neuron projection membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0009986//cell surface;GO:0005615//extracellular space,GO:0008406//gonad development;GO:0022601//menstrual cycle phase;GO:2000119//negative regulation of sodium-dependent phosphate transport;GO:0002092//positive regulation of receptor internalization;GO:0043065//positive regulation of apoptotic process;GO:0046329//negative regulation of JNK cascade;GO:0046697//decidualization;GO:0001944//vasculature development;GO:0060429//epithelium development;GO:0055062//phosphate ion homeostasis;GO:0016055//Wnt signaling pathway;GO:0009725//response to hormone;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:1902174//positive regulation of keratinocyte apoptotic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0045606//positive regulation of epidermal cell differentiation;GO:0007420//brain development;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0060056//mammary gland involution;GO:0007409//axonogenesis,GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity,K02185//Wnt signaling pathway
64240,36,0,0,0,8,14,0,0,19,0,35,0,"ABCG5;ATP-binding cassette, sub-family G (WHITE), member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0042632//cholesterol homeostasis;GO:0007584//response to nutrient;GO:0007588//excretion;GO:0030299//intestinal cholesterol absorption;GO:0055085//transmembrane transport;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0042493//response to drug;GO:0010949//negative regulation of intestinal phytosterol absorption;GO:0033344//cholesterol efflux;GO:0010212//response to ionizing radiation;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0017127//cholesterol transporter activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0016887//ATPase activity,K05683//ABC transporters;Fat digestion and absorption;Bile secretion
642402,3,0,0,0,0,1,0,0,0,0,0,3,"GOLGA6L17P;golgin A6 family-like 17, pseudogene",-,-,-,-
64241,1,0,0,0,5,0,0,1,11,0,3,0,"ABCG8;ATP-binding cassette, sub-family G (WHITE), member 8",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0016324//apical plasma membrane,GO:0030299//intestinal cholesterol absorption;GO:0055085//transmembrane transport;GO:0015914//phospholipid transport;GO:0045796//negative regulation of intestinal cholesterol absorption;GO:0007588//excretion;GO:0007584//response to nutrient;GO:0042632//cholesterol homeostasis;GO:0033344//cholesterol efflux;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0042493//response to drug;GO:0010949//negative regulation of intestinal phytosterol absorption,GO:0017127//cholesterol transporter activity;GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K05684//Bile secretion;ABC transporters;Fat digestion and absorption
642446,0,0,0,0,0,56,9,0,28,10,19,0,TRIM64B;tripartite motif containing 64B,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
642475,0,0,0,0,0,0,0,0,7,0,0,0,MROH6;maestro heat-like repeat family member 6,-,-,-,-
6425,0,0,0,0,0,0,15,0,29,0,0,0,SFRP5;secreted frizzled-related protein 5,GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0042995//cell projection;GO:0005737//cytoplasm,GO:0007601//visual perception;GO:0007165//signal transduction;GO:2000057//negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0051898//negative regulation of protein kinase B signaling;GO:0030154//cell differentiation;GO:0048546//digestive tract morphogenesis;GO:0001944//vasculature development;GO:0006915//apoptotic process;GO:0008406//gonad development;GO:2000041//negative regulation of planar cell polarity pathway involved in axis elongation;GO:0036342//post-anal tail morphogenesis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0007163//establishment or maintenance of cell polarity;GO:0008285//negative regulation of cell proliferation;GO:0035414//negative regulation of catenin import into nucleus;GO:0007420//brain development;GO:0009653//anatomical structure morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043508//negative regulation of JUN kinase activity;GO:0060028//convergent extension involved in axis elongation,GO:0017147//Wnt-protein binding;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding,K02222//Wnt signaling pathway
642517,0,0,0,0,0,9,0,2,36,0,0,0,"AGAP9;ArfGAP with GTPase domain, ankyrin repeat and PH domain 9",-,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K12491//Endocytosis
642559,0,0,0,0,0,0,16,0,0,0,0,0,POU5F1P3;POU class 5 homeobox 1 pseudogene 3,-,-,-,-
642569,0,0,0,0,0,36,0,0,17,0,0,0,"TRIM53AP;tripartite motif containing 53A, pseudogene",-,-,-,-
642597,0,0,0,0,0,0,0,0,12,0,0,0,C18orf42;chromosome 18 open reading frame 42,-,-,-,-
6426,54,140,65,84,257,10,45,0,55,0,19,0,SRSF1;serine/arginine-rich splicing factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0035145//exon-exon junction complex;GO:0070062//extracellular vesicular exosome;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome,"GO:0043488//regulation of mRNA stability;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition;GO:0006417//regulation of translation;GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0001701//in utero embryonic development;GO:0006406//mRNA export from nucleus;GO:0006376//mRNA splice site selection;GO:0060048//cardiac muscle contraction;GO:0006355//regulation of transcription, DNA-templated;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0031124//mRNA 3'-end processing",GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0003729//mRNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12890//Spliceosome;Herpes simplex infection
642612,0,0,0,0,0,0,0,0,0,129,0,0,TRIM49C;tripartite motif containing 49C,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
642633,0,0,0,0,0,0,0,0,30,0,0,0,"FAM230B;family with sequence similarity 230, member B (non-protein coding)",-,-,-,K06236//ECM-receptor interaction;Amoebiasis;Protein digestion and absorption;Focal adhesion
642636,0,0,0,0,0,10,0,42,35,4,0,0,RAD21L1;RAD21-like 1 (S. pombe),GO:0034991//nuclear meiotic cohesin complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0030893//meiotic cohesin complex;GO:0005694//chromosome,GO:0070197//attachment of telomeric heterochromatin to nuclear envelope;GO:0030999//linear element assembly;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0007059//chromosome segregation;GO:0072520//seminiferous tubule development;GO:0000724//double-strand break repair via homologous recombination,-,K06670//Cell cycle;Cell cycle - yeast
6427,0,64,1,17,61,0,0,0,26,0,40,0,SRSF2;serine/arginine-rich splicing factor 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0070062//extracellular vesicular exosome;GO:0016605//PML body;GO:0016607//nuclear speck,"GO:0031124//mRNA 3'-end processing;GO:0006406//mRNA export from nucleus;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:2001141//regulation of RNA biosynthetic process;GO:0006369//termination of RNA polymerase II transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity,K12891//Herpes simplex infection;Spliceosome
642757,0,0,44,0,0,17,0,0,0,0,0,0,LOC642757;uncharacterized LOC642757,-,-,-,K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
6428,0,40,3,73,139,0,0,64,27,0,0,0,SRSF3;serine/arginine-rich splicing factor 3,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck,"GO:0006366//transcription from RNA polymerase II promoter;GO:0006406//mRNA export from nucleus;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0043274//phospholipase binding;GO:0003723//RNA binding,K12892//Herpes simplex infection;Spliceosome
64282,0,0,0,25,16,6,0,0,28,0,10,0,PAPD5;PAP associated domain containing 5,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0006397//mRNA processing;GO:0006261//DNA-dependent DNA replication;GO:0007067//mitotic nuclear division;GO:0071044//histone mRNA catabolic process;GO:0006364//rRNA processing,GO:0003677//DNA binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0003887//DNA-directed DNA polymerase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,K03514//RNA degradation
642826,0,0,0,0,0,1,1,0,8,0,0,0,BMS1P6;BMS1 pseudogene 6,-,-,-,K14569//Ribosome biogenesis in eukaryotes
64283,93,0,0,10,0,18,41,112,52,0,0,0,ARHGEF28;Rho guanine nucleotide exchange factor (GEF) 28,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0032321//positive regulation of Rho GTPase activity;GO:0021955//central nervous system neuron axonogenesis;GO:0060052//neurofilament cytoskeleton organization;GO:0035556//intracellular signal transduction,GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12791//Pathogenic Escherichia coli infection
64284,0,0,0,0,9,2,10,0,16,0,3,0,"RAB17;RAB17, member RAS oncogene family",GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0042470//melanosome;GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0005622//intracellular;GO:0030139//endocytic vesicle;GO:0016323//basolateral plasma membrane,GO:0006184//GTP catabolic process;GO:0042384//cilium assembly;GO:0015031//protein transport;GO:0051489//regulation of filopodium assembly;GO:0051963//regulation of synapse assembly;GO:0032456//endocytic recycling;GO:0050773//regulation of dendrite development;GO:0032401//establishment of melanosome localization;GO:0007264//small GTPase mediated signal transduction;GO:0045056//transcytosis;GO:0002415//immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor;GO:0046847//filopodium assembly;GO:0032402//melanosome transport,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
642843,0,94,57,60,142,0,0,0,21,0,134,0,CPSF4L;cleavage and polyadenylation specific factor 4-like,-,-,GO:0046872//metal ion binding;GO:0003723//RNA binding,K14404//mRNA surveillance pathway;Influenza A
642846,0,0,0,0,0,20,0,1,70,0,2,0,LOC642846;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11-like,-,-,-,-
64285,0,0,0,0,1,0,20,0,1,0,1,0,RHBDF1;rhomboid 5 homolog 1 (Drosophila),GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0050708//regulation of protein secretion;GO:0061136//regulation of proteasomal protein catabolic process;GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0016477//cell migration;GO:0015031//protein transport;GO:0006508//proteolysis;GO:0050709//negative regulation of protein secretion;GO:0008283//cell proliferation,GO:0004252//serine-type endopeptidase activity;GO:0019838//growth factor binding,K02857//Dorso-ventral axis formation
64288,74,22,0,1,33,8,0,0,6,0,0,1,ZSCAN31;zinc finger and SCAN domain containing 31,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
6429,0,16,39,7,37,0,8,0,20,0,0,0,SRSF4;serine/arginine-rich splicing factor 4,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0002244//hematopoietic progenitor cell differentiation",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K12893//Spliceosome;Herpes simplex infection
642929,0,0,0,0,0,0,30,0,0,0,0,0,"LOC642929;general transcription factor II, i pseudogene",-,-,-,-
642938,0,0,0,0,0,10,0,0,0,0,7,0,"FAM196A;family with sequence similarity 196, member A",-,-,-,-
642943,0,0,0,0,0,28,0,0,33,0,6,0,LOC642943;SPATA31 subfamily A pseudogene,-,-,-,-
642968,0,0,0,0,0,0,31,0,9,0,0,0,"FAM163B;family with sequence similarity 163, member B",GO:0016021//integral component of membrane,-,-,-
642987,0,0,0,0,0,0,0,0,5,0,0,0,TMEM232;transmembrane protein 232,GO:0016021//integral component of membrane,-,-,-
643,0,0,0,2,0,0,0,0,14,8,2,0,CXCR5;chemokine (C-X-C motif) receptor 5,GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0070098//chemokine-mediated signaling pathway;GO:0006935//chemotaxis;GO:0048535//lymph node development;GO:0006955//immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006928//cellular component movement;GO:0032467//positive regulation of cytokinesis;GO:0042113//B cell activation,GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0016494//C-X-C chemokine receptor activity,K04190//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
6430,0,17,1,19,100,1,0,0,46,0,0,0,SRSF5;serine/arginine-rich splicing factor 5,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005730//nucleolus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0051726//regulation of cell cycle;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006406//mRNA export from nucleus;GO:0006376//mRNA splice site selection;GO:0031124//mRNA 3'-end processing;GO:0009611//response to wounding",GO:0050733//RS domain binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12893//Herpes simplex infection;Spliceosome
643008,0,0,39,5,0,7,80,90,19,0,6,0,SMIM5;small integral membrane protein 5,GO:0016021//integral component of membrane,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption
6431,0,82,2,107,215,0,0,0,25,0,1,0,SRSF6;serine/arginine-rich splicing factor 6,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0031124//mRNA 3'-end processing;GO:0010837//regulation of keratinocyte proliferation;GO:0006376//mRNA splice site selection;GO:0006406//mRNA export from nucleus;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0061041//regulation of wound healing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0060548//negative regulation of cell death;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0045617//negative regulation of keratinocyte differentiation;GO:0000380//alternative mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0036002//pre-mRNA binding,K12893//Spliceosome;Herpes simplex infection
643155,61,49,0,45,206,0,0,0,0,0,0,0,SMIM15;small integral membrane protein 15,GO:0016021//integral component of membrane,-,-,-
643161,0,0,0,0,0,0,0,0,6,0,13,0,"FAM25A;family with sequence similarity 25, member A",-,-,-,-
64318,10,9,0,0,6,20,0,0,34,0,4,0,NOC3L;nucleolar complex associated 3 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0016607//nuclear speck,GO:0045444//fat cell differentiation,GO:0044822//poly(A) RNA binding,-
643180,1,0,18,0,0,0,0,0,0,0,0,0,"CCT6P3;chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3",-,-,-,-
64319,87,0,0,0,14,0,0,0,0,220,0,0,FBRS;fibrosin,-,-,-,-
6432,0,74,1,32,28,0,0,0,0,0,0,0,SRSF7;serine/arginine-rich splicing factor 7,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,"GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0048025//negative regulation of mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,K12896//Spliceosome;Herpes simplex infection
64320,0,0,0,0,11,0,0,0,0,0,1,0,RNF25;ring finger protein 25,GO:0005829//cytosol;GO:0005634//nucleus,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0051059//NF-kappaB binding,-
643201,0,0,0,0,0,0,2,0,0,0,0,0,LOC643201;centrosomal protein 192kDa pseudogene,-,-,-,K14299//RNA transport
64321,0,0,0,0,0,0,37,20,2,7,13,0,SOX17;SRY (sex determining region Y)-box 17,GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005667//transcription factor complex,"GO:0061031//endodermal digestive tract morphogenesis;GO:0007283//spermatogenesis;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0048617//embryonic foregut morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0035050//embryonic heart tube development;GO:0003142//cardiogenic plate morphogenesis;GO:0060956//endocardial cell differentiation;GO:0042662//negative regulation of mesodermal cell fate specification;GO:0042074//cell migration involved in gastrulation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0061009//common bile duct development;GO:0060913//cardiac cell fate determination;GO:0030308//negative regulation of cell growth;GO:0060914//heart formation;GO:0072091//regulation of stem cell proliferation;GO:0001525//angiogenesis;GO:0045597//positive regulation of cell differentiation;GO:0045995//regulation of embryonic development;GO:0048866//stem cell fate specification;GO:0060214//endocardium formation;GO:0031648//protein destabilization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000035//regulation of stem cell division;GO:0048643//positive regulation of skeletal muscle tissue development;GO:0021903//rostrocaudal neural tube patterning;GO:0001706//endoderm formation;GO:0003143//embryonic heart tube morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0060807//regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification;GO:0001947//heart looping;GO:0050821//protein stabilization;GO:0023019//signal transduction involved in regulation of gene expression;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0072001//renal system development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061010//gall bladder development;GO:0045732//positive regulation of protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0001570//vasculogenesis",GO:0043565//sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0008013//beta-catenin binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding,K04495//Wnt signaling pathway
643210,0,0,0,0,0,0,0,0,0,154,0,0,EHMT1-IT1;EHMT1 intronic transcript 1,-,-,-,-
643224,0,0,0,5,11,10,0,0,0,0,0,0,"TUBBP5;tubulin, beta pseudogene 5",-,-,-,K07375//Phagosome;Gap junction;Pathogenic Escherichia coli infection
643226,0,0,0,0,0,0,0,0,12,0,0,0,"GRXCR2;glutaredoxin, cysteine rich 2",-,-,GO:0051082//unfolded protein binding;GO:0031072//heat shock protein binding,-
643236,0,0,0,0,0,0,34,2,37,0,21,0,TMEM72;transmembrane protein 72,GO:0016021//integral component of membrane,-,-,-
64324,0,35,0,23,209,54,2,0,47,0,0,0,NSD1;nuclear receptor binding SET domain protein 1,GO:0005694//chromosome;GO:0005634//nucleus,"GO:0010452//histone H3-K36 methylation;GO:0034770//histone H4-K20 methylation;GO:0001702//gastrulation with mouth forming second;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation",GO:0008270//zinc ion binding;GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0046965//retinoid X receptor binding;GO:0003712//transcription cofactor activity;GO:0030331//estrogen receptor binding;GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0050681//androgen receptor binding;GO:0042974//retinoic acid receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity,K15588//Lysine degradation
643246,0,0,0,1,0,11,31,0,0,0,4,0,MAP1LC3B2;microtubule-associated protein 1 light chain 3 beta 2,GO:0012505//endomembrane system;GO:0031410//cytoplasmic vesicle;GO:0005874//microtubule;GO:0000421//autophagic vacuole membrane,GO:0006914//autophagy,-,-
643253,0,0,0,0,0,6,0,0,0,0,0,0,"CCT6P1;chaperonin containing TCP1, subunit 6 (zeta) pseudogene 1",-,-,-,-
64326,0,0,0,1,40,2,11,0,70,0,0,0,"RFWD2;ring finger and WD repeat domain 2, E3 ubiquitin protein ligase",GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0010212//response to ionizing radiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination",GO:0008270//zinc ion binding;GO:0061630//ubiquitin protein ligase activity;GO:0005515//protein binding;GO:0016874//ligase activity,K10143//Ubiquitin mediated proteolysis;p53 signaling pathway
64327,0,18,0,8,44,0,13,0,11,0,0,0,LMBR1;limb development membrane protein 1,GO:0016021//integral component of membrane,GO:0042733//embryonic digit morphogenesis,-,-
64328,0,0,0,19,41,12,0,0,49,0,0,0,XPO4;exportin 4,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0046827//positive regulation of protein export from nucleus,GO:0005515//protein binding,-
6433,0,0,0,9,12,0,0,0,34,0,13,0,"SFSWAP;splicing factor, suppressor of white-apricot family",GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0006355//regulation of transcription, DNA-templated;GO:0006376//mRNA splice site selection;GO:0006351//transcription, DNA-templated",GO:0003723//RNA binding,-
643311,0,0,0,0,0,27,20,0,3,0,0,0,"CT47B1;cancer/testis antigen family 47, member B1",-,-,-,-
643314,2,1,0,0,13,0,0,0,22,0,0,0,KIAA0754;KIAA0754,-,-,-,K11447//Transcriptional misregulation in cancer;K00797//beta-Alanine metabolism;Metabolic pathways;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
64332,1,0,26,0,16,0,3,0,27,0,0,138,"NFKBIZ;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta",GO:0005634//nucleus,"GO:0006954//inflammatory response;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,K14242//Transcriptional misregulation in cancer
64333,0,0,0,0,0,0,0,0,14,160,0,0,ARHGAP9;Rho GTPase activating protein 9,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,"GO:0005096//GTPase activator activity;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding",K07526//Axon guidance;K04450//Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;Alcoholism;Influenza A;K08878//Chronic myeloid leukemia;Pathways in cancer
643338,0,0,0,0,8,7,55,96,8,16,25,0,C15orf62;chromosome 15 open reading frame 62,GO:0005739//mitochondrion,-,-,-
643365,0,0,0,0,0,0,0,0,13,0,0,0,LINC00452;long intergenic non-protein coding RNA 452,-,-,-,-
643376,0,1,0,11,39,28,0,0,24,0,0,0,BTBD18;BTB (POZ) domain containing 18,-,-,-,-
643387,0,0,0,0,0,0,0,0,4,0,0,0,LOC643387;TAR DNA binding protein pseudogene,-,-,-,-
643394,0,0,0,0,0,0,0,0,13,0,0,0,"SPINK9;serine peptidase inhibitor, Kazal type 9",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,-
6434,0,0,0,19,56,20,93,0,9,0,0,0,TRA2B;transformer 2 beta homolog (Drosophila),GO:0005634//nucleus,"GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding,K12897//Spliceosome
643401,0,0,0,0,0,0,0,0,0,0,14,0,LINC01021;long intergenic non-protein coding RNA 1021,-,-,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
643406,0,0,0,0,0,0,24,0,29,0,0,0,LOC643406;uncharacterized LOC643406,-,-,-,K09299//Transcriptional misregulation in cancer;K00543//Tryptophan metabolism;Metabolic pathways;K04257//Olfactory transduction
643414,0,0,0,0,0,0,17,0,13,0,0,0,"LIPK;lipase, family member K",GO:0005576//extracellular region,GO:0016042//lipid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds",K14452//Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption
643418,0,0,0,0,0,35,0,0,0,0,0,0,"LIPN;lipase, family member N",GO:0005576//extracellular region,GO:0016042//lipid catabolic process,"GO:0016788//hydrolase activity, acting on ester bonds",K01052//Steroid biosynthesis;Lysosome;K14452//Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption
64342,0,30,0,1,3,22,0,1,0,1,10,0,HS1BP3;HCLS1 binding protein 3,-,-,GO:0035091//phosphatidylinositol binding,-
64343,0,0,0,33,105,0,21,0,0,0,0,0,AZI2;5-azacytidine induced 2,GO:0005737//cytoplasm,GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032609//interferon-gamma production;GO:0042110//T cell activation;GO:0097028//dendritic cell differentiation;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K12651//RIG-I-like receptor signaling pathway
64344,0,0,0,0,0,14,18,23,33,106,4,0,"HIF3A;hypoxia inducible factor 3, alpha subunit",GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0003714//transcription corepressor activity;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0004871//signal transducer activity;GO:0003677//DNA binding,-
64359,4,1,1,21,68,0,1,0,1,0,14,0,NXN;nucleoredoxin,GO:0005829//cytosol;GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0055114//oxidation-reduction process;GO:0072358//cardiovascular system development;GO:0031397//negative regulation of protein ubiquitination;GO:0030178//negative regulation of Wnt signaling pathway;GO:0016055//Wnt signaling pathway,GO:0047134//protein-disulfide reductase activity;GO:0004791//thioredoxin-disulfide reductase activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
643596,35,0,0,0,0,0,28,0,0,0,0,0,RNF224;ring finger protein 224,-,-,GO:0008270//zinc ion binding,K14683//Mineral absorption
643641,80,0,0,0,0,0,7,46,39,0,40,0,ZNF862;zinc finger protein 862,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity,-
643664,0,0,0,0,0,0,11,0,0,0,0,0,"SLC35G6;solute carrier family 35, member G6",GO:0016021//integral component of membrane,-,-,-
643669,0,0,0,0,0,0,0,0,16,15,1,0,CCER2;coiled-coil glutamate-rich protein 2,GO:0005576//extracellular region,-,-,-
643677,0,0,0,0,0,56,102,151,156,53,0,0,CCDC168;coiled-coil domain containing 168,-,-,-,K00907//Calcium signaling pathway;Gastric acid secretion;Focal adhesion;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
643699,0,0,0,0,15,0,0,2,0,0,0,0,"GOLGA8N;golgin A8 family, member N",GO:0005794//Golgi apparatus,-,-,K12478//Tuberculosis;Phagosome;Endocytosis
643707,1,0,0,0,0,1,0,2,2,0,0,0,GOLGA6L4;golgin A6 family-like 4,-,-,-,-
643719,0,0,0,0,0,53,0,0,0,0,0,0,"SCGB1B2P;secretoglobin, family 1B, member 2, pseudogene",-,-,-,-
643733,0,0,0,11,0,13,0,0,0,0,0,0,"LOC643733;caspase 4, apoptosis-related cysteine peptidase pseudogene",-,-,-,-
64374,0,0,0,0,0,0,23,0,14,0,0,0,SIL1;SIL1 nucleotide exchange factor,GO:0005788//endoplasmic reticulum lumen;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space,GO:0006886//intracellular protein transport;GO:0006457//protein folding,GO:0051082//unfolded protein binding,K14001//Protein processing in endoplasmic reticulum
64375,0,0,0,0,0,0,0,0,42,0,4,0,IKZF4;IKAROS family zinc finger 4 (Eos),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated",GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
64376,0,32,1,60,65,1,0,1,29,77,0,0,IKZF5;IKAROS family zinc finger 5 (Pegasus),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
64377,0,0,0,0,0,0,0,1,16,0,0,0,CHST8;carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030166//proteoglycan biosynthetic process;GO:0016051//carbohydrate biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0042446//hormone biosynthetic process;GO:0007417//central nervous system development,GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity,-
643802,17,0,0,0,0,0,0,0,0,0,0,0,LOC643802;u3 small nucleolar ribonucleoprotein protein MPP10-like,-,-,-,K14559//Ribosome biogenesis in eukaryotes
643803,0,0,0,0,0,0,0,0,31,0,0,0,KRTAP24-1;keratin associated protein 24-1,GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
643834,0,0,0,0,0,30,0,0,17,0,7,0,"PGA3;pepsinogen 3, group I (pepsinogen A)",GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0007586//digestion,GO:0004190//aspartic-type endopeptidase activity,K06002//Protein digestion and absorption
643836,0,16,12,6,64,0,14,0,13,0,14,0,ZFP62;ZFP62 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
643847,0,0,0,0,0,0,0,0,0,0,1,0,"PGA4;pepsinogen 4, group I (pepsinogen A)",GO:0070062//extracellular vesicular exosome,GO:0007586//digestion;GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity,K06002//Protein digestion and absorption
643853,0,0,0,0,0,28,31,0,50,0,0,0,TMPPE;transmembrane protein with metallophosphoesterase domain,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,-
643854,99,1,0,30,1,0,12,1,0,0,11,0,"CTAGE9;CTAGE family, member 9",GO:0016021//integral component of membrane,-,-,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
64386,20,0,0,20,0,10,30,104,38,0,39,0,MMP25;matrix metallopeptidase 25,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane,GO:0006954//inflammatory response;GO:0060022//hard palate development;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
643866,0,0,25,0,0,0,0,0,0,0,3,0,CBLN3;cerebellin 3 precursor,GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0045202//synapse;GO:0030054//cell junction;GO:0005794//Golgi apparatus,-,-,-
64388,0,44,0,0,0,0,0,0,6,0,0,1,"GREM2;gremlin 2, DAN family BMP antagonist",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0038098//sequestering of BMP from receptor via BMP binding;GO:0019221//cytokine-mediated signaling pathway;GO:0060300//regulation of cytokine activity;GO:0030509//BMP signaling pathway;GO:0048263//determination of dorsal identity;GO:0010172//embryonic body morphogenesis,GO:0005125//cytokine activity;GO:0008201//heparin binding;GO:0042803//protein homodimerization activity;GO:0036122//BMP binding,K01645//Wnt signaling pathway
6439,0,0,0,0,0,3,0,0,17,0,0,10,SFTPB;surfactant protein B,GO:0005615//extracellular space;GO:0005764//lysosome,GO:0007585//respiratory gaseous exchange;GO:0006665//sphingolipid metabolic process;GO:0009887//organ morphogenesis,-,K12382//Lysosome
643904,0,0,0,0,0,0,11,0,23,0,0,0,RNF222;ring finger protein 222,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
643905,0,0,0,0,0,8,0,0,14,0,0,0,PRR21;proline rich 21,-,-,-,K12826//Spliceosome
64393,0,1,0,31,10,50,0,0,79,0,0,0,"ZMAT3;zinc finger, matrin-type 3",GO:0005730//nucleolus,GO:0015031//protein transport;GO:0043065//positive regulation of apoptotic process;GO:0040008//regulation of growth;GO:0006974//cellular response to DNA damage stimulus;GO:0006915//apoptotic process,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K10137//p53 signaling pathway
64395,0,0,0,5,5,0,0,0,70,0,4,0,"GMCL1;germ cell-less, spermatogenesis associated 1",GO:0005635//nuclear envelope;GO:0016363//nuclear matrix,"GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030154//cell differentiation",-,-
643955,0,0,0,0,0,0,0,0,0,0,13,0,"ZNF733P;zinc finger protein 733, pseudogene",-,-,-,-
64396,0,0,0,0,0,0,0,0,9,0,11,0,"GMCL1P1;germ cell-less, spermatogenesis associated 1 pseudogene 1",GO:0016363//nuclear matrix,GO:0030154//cell differentiation;GO:0016567//protein ubiquitination;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0005515//protein binding,-
643965,0,0,0,0,0,0,0,0,11,0,0,0,TMEM88B;transmembrane protein 88B,GO:0016021//integral component of membrane,-,-,-
64397,0,62,1,158,301,0,86,0,54,0,1,0,ZNF106;zinc finger protein 106,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0016020//membrane,GO:0008286//insulin receptor signaling pathway,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0001515//opioid peptide activity;GO:0017124//SH3 domain binding,K10260//Ubiquitin mediated proteolysis
64398,0,84,80,198,370,26,14,0,36,0,181,0,"MPP5;membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)",GO:0005730//nucleolus;GO:0005923//tight junction;GO:0043220//Schmidt-Lanterman incisure;GO:0043219//lateral loop;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0035749//myelin sheath adaxonal region;GO:0005737//cytoplasm,GO:0032287//peripheral nervous system myelin maintenance;GO:0045216//cell-cell junction organization;GO:0070830//tight junction assembly;GO:0002011//morphogenesis of an epithelial sheet;GO:0034329//cell junction assembly;GO:0090002//establishment of protein localization to plasma membrane;GO:0035750//protein localization to myelin sheath abaxonal region;GO:0032288//myelin assembly,GO:0005515//protein binding;GO:0019904//protein domain specific binding,K06091//Tight junction
643988,0,0,0,0,0,0,0,0,0,0,0,362,C1orf233;chromosome 1 open reading frame 233,GO:0016021//integral component of membrane,-,-,-
64399,0,0,0,0,0,0,1,0,63,0,34,0,HHIP;hedgehog interacting protein,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005576//extracellular region,GO:0045879//negative regulation of smoothened signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0055114//oxidation-reduction process;GO:0009953//dorsal/ventral pattern formation;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0048705//skeletal system morphogenesis;GO:0007405//neuroblast proliferation;GO:0007224//smoothened signaling pathway;GO:0005975//carbohydrate metabolic process;GO:0060441//epithelial tube branching involved in lung morphogenesis,"GO:0097108//hedgehog family protein binding;GO:0048038//quinone binding;GO:0008270//zinc ion binding;GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0005515//protein binding",K06231//Hedgehog signaling pathway;Pathways in cancer;Basal cell carcinoma
644,0,0,0,7,29,22,0,13,30,147,0,0,BLVRA;biliverdin reductase A,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0042167//heme catabolic process;GO:0055114//oxidation-reduction process;GO:0006778//porphyrin-containing compound metabolic process;GO:0044281//small molecule metabolic process,GO:0004074//biliverdin reductase activity;GO:0008270//zinc ion binding,K00214//Porphyrin and chlorophyll metabolism
6440,0,0,0,0,0,0,9,76,17,0,0,0,SFTPC;surfactant protein C,GO:0005615//extracellular space;GO:0005771//multivesicular body;GO:0097208//alveolar lamellar body,GO:0007623//circadian rhythm;GO:0071260//cellular response to mechanical stimulus;GO:0070848//response to growth factor;GO:0032496//response to lipopolysaccharide;GO:0051384//response to glucocorticoid;GO:0055093//response to hyperoxia;GO:0033189//response to vitamin A;GO:0070741//response to interleukin-6;GO:0032526//response to retinoic acid;GO:0071732//cellular response to nitric oxide;GO:0007585//respiratory gaseous exchange;GO:0051591//response to cAMP;GO:0009749//response to glucose;GO:0051260//protein homooligomerization,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
64400,0,0,0,3,32,0,42,75,0,0,11,0,AKTIP;AKT interacting protein,GO:0030897//HOPS complex;GO:0070695//FHF complex;GO:0005886//plasma membrane,GO:0001934//positive regulation of protein phosphorylation;GO:0008152//metabolic process;GO:0015031//protein transport;GO:0007040//lysosome organization;GO:0045022//early endosome to late endosome transport;GO:0032092//positive regulation of protein binding;GO:0008333//endosome to lysosome transport;GO:0006915//apoptotic process;GO:0007032//endosome organization,GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity,K10576//Ubiquitin mediated proteolysis;K02207//Ubiquitin mediated proteolysis;Herpes simplex infection
644019,0,0,0,0,0,0,1,0,0,0,0,0,CBWD6;COBW domain containing 6,-,-,GO:0005524//ATP binding,-
64403,0,0,0,0,0,46,10,0,26,2,0,416,"CDH24;cadherin 24, type 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005911//cell-cell junction,GO:0034332//adherens junction organization;GO:0016337//single organismal cell-cell adhesion;GO:0034329//cell junction assembly;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0045216//cell-cell junction organization,GO:0005509//calcium ion binding;GO:0045294//alpha-catenin binding;GO:0008013//beta-catenin binding;GO:0070097//delta-catenin binding,-
644041,0,0,0,0,0,1,0,0,70,140,12,1,C18orf63;chromosome 18 open reading frame 63,-,-,-,-
64405,0,0,0,0,0,24,0,7,19,127,11,0,"CDH22;cadherin 22, type 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007420//brain development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
64407,0,0,0,0,0,0,0,0,11,200,0,0,RGS18;regulator of G-protein signaling 18,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K07524//Axon guidance
64409,7,1,0,0,8,18,1,0,26,0,0,0,WBSCR17;Williams-Beuren syndrome chromosome region 17,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation,GO:0046872//metal ion binding;GO:0030246//carbohydrate binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways
644096,132,0,0,0,0,0,0,0,2,0,0,0,SDHAF1;succinate dehydrogenase complex assembly factor 1,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0016226//iron-sulfur cluster assembly,-,-
6441,0,0,0,0,0,0,22,0,23,0,0,0,SFTPD;surfactant protein D,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030139//endocytic vesicle;GO:0005581//collagen trimer;GO:0005764//lysosome;GO:0005578//proteinaceous extracellular matrix,GO:0072593//reactive oxygen species metabolic process;GO:0050766//positive regulation of phagocytosis;GO:0048286//lung alveolus development;GO:0043129//surfactant homeostasis;GO:0045087//innate immune response;GO:0007585//respiratory gaseous exchange;GO:0048246//macrophage chemotaxis;GO:0042742//defense response to bacterium;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0001817//regulation of cytokine production;GO:0006898//receptor-mediated endocytosis;GO:0042130//negative regulation of T cell proliferation,GO:0030246//carbohydrate binding;GO:0005515//protein binding,K10068//Phagosome
64410,0,0,0,0,0,0,0,0,24,0,0,0,KLHL25;kelch-like family member 25,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006446//regulation of translational initiation;GO:0016567//protein ubiquitination,-,-
64411,0,0,0,0,1,11,25,2,49,0,0,0,"ARAP3;ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3",GO:0001726//ruffle;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0008360//regulation of cell shape;GO:0030336//negative regulation of cell migration;GO:0007010//cytoskeleton organization;GO:0035024//negative regulation of Rho protein signal transduction;GO:0032312//regulation of ARF GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0035021//negative regulation of Rac protein signal transduction,"GO:0005100//Rho GTPase activator activity;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030675//Rac GTPase activator activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding",K12490//Endocytosis
64412,0,0,0,0,32,1,0,1,20,0,0,486,GZF1;GDNF-inducible zinc finger protein 1,GO:0005730//nucleolus;GO:0005654//nucleoplasm,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding,-
644139,0,0,0,0,0,0,0,0,0,105,0,0,PIRT;phosphoinositide-interacting regulator of transient receptor potential channels,GO:0016021//integral component of membrane,-,-,-
644145,0,0,0,0,0,0,0,0,22,0,0,0,LOC644145;exocyst complex component 1 pseudogene,-,-,-,-
644150,0,0,0,0,0,56,64,0,30,0,0,0,"WIPF3;WAS/WASL interacting protein family, member 3",GO:0005829//cytosol,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0030154//cell differentiation;GO:0045087//innate immune response,GO:0003779//actin binding,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
644165,0,16,0,0,0,0,15,20,20,0,0,0,BCRP3;breakpoint cluster region pseudogene 3,-,-,-,K08878//Pathways in cancer;Chronic myeloid leukemia
64417,0,0,0,0,0,5,25,0,0,0,0,0,C5orf28;chromosome 5 open reading frame 28,GO:0016021//integral component of membrane,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
644172,0,1,0,0,0,30,0,1,1,0,0,0,LOC644172;mitogen-activated protein kinase 8 interacting protein 1 pseudogene,-,-,-,K04434//MAPK signaling pathway
64418,0,0,0,0,23,13,44,0,52,0,25,0,TMEM168;transmembrane protein 168,GO:0016021//integral component of membrane;GO:0030133//transport vesicle,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
644189,102,0,0,0,0,0,0,0,4,0,0,0,LOC644189;acyl-CoA thioesterase 4 pseudogene,-,-,-,K01068//Fatty acid elongation;Biosynthesis of secondary metabolites;Biosynthesis of unsaturated fatty acids
64419,0,0,0,0,1,0,23,0,0,0,0,1,MTMR14;myotubularin related protein 14,GO:0005829//cytosol;GO:0001726//ruffle;GO:0048471//perinuclear region of cytoplasm,GO:0044281//small molecule metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006644//phospholipid metabolic process,GO:0004725//protein tyrosine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity,-
6442,115,0,44,0,0,1,0,43,10,0,0,0,"SGCA;sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)",GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0016012//sarcoglycan complex;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0042383//sarcolemma,GO:0007517//muscle organ development;GO:0006936//muscle contraction,GO:0005509//calcium ion binding,K12565//Dilated cardiomyopathy;Viral myocarditis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
64420,77,0,0,9,0,16,29,0,22,0,16,0,SUSD1;sushi domain containing 1,GO:0016021//integral component of membrane,-,GO:0005509//calcium ion binding,-
64421,0,53,82,159,95,38,0,54,2,0,142,1,DCLRE1C;DNA cross-link repair 1C,GO:0005634//nucleus,"GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0010212//response to ionizing radiation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000723//telomere maintenance;GO:0030183//B cell differentiation;GO:0000737//DNA catabolic process, endonucleolytic",GO:0008409//5'-3' exonuclease activity;GO:0000014//single-stranded DNA endodeoxyribonuclease activity,K10887//Non-homologous end-joining;Primary immunodeficiency
64422,0,0,0,7,17,0,0,0,0,0,0,2,ATG3;autophagy related 3,GO:0005829//cytosol;GO:0000153//cytoplasmic ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0000422//mitochondrion degradation;GO:1902017//regulation of cilium assembly;GO:0006612//protein targeting to membrane;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0000045//autophagic vacuole assembly;GO:0006464//cellular protein modification process,GO:0019777//Atg12 ligase activity;GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity;GO:0019899//enzyme binding;GO:0019776//Atg8 ligase activity,K08343//Regulation of autophagy
64423,38,0,0,13,0,0,14,0,21,0,25,0,"INF2;inverted formin, FH2 and WH2 domain containing",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum,GO:0032535//regulation of cellular component size;GO:0030036//actin cytoskeleton organization;GO:0090140//regulation of mitochondrial fission;GO:0008219//cell death,GO:0017048//Rho GTPase binding;GO:0003779//actin binding,K05745//Regulation of actin cytoskeleton;K05740//Focal adhesion;Shigellosis;Regulation of actin cytoskeleton;K05741//Regulation of actin cytoskeleton;K04512//Wnt signaling pathway
64425,0,24,0,13,0,26,5,0,4,0,0,0,"POLR1E;polymerase (RNA) I polypeptide E, 53kDa",GO:0005736//DNA-directed RNA polymerase I complex;GO:0005730//nucleolus,GO:0001189//RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript;GO:0009303//rRNA transcription,GO:0001054//RNA polymerase I activity;GO:0003677//DNA binding,K03005//RNA polymerase;Purine metabolism;Pyrimidine metabolism;Metabolic pathways
64426,0,6,1,36,215,1,0,56,31,0,0,0,SUDS3;suppressor of defective silencing 3 homolog (S. cerevisiae),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016580//Sin3 complex;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0021762//substantia nigra development;GO:0043065//positive regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation",GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004407//histone deacetylase activity,-
64427,0,0,0,0,0,0,0,0,15,0,0,0,TTC31;tetratricopeptide repeat domain 31,-,-,-,K09553//Prion diseases
64428,0,1,0,1,0,10,0,56,24,0,1,0,NARFL;nuclear prelamin A recognition factor-like,GO:0097361//CIA complex,"GO:0001666//response to hypoxia;GO:0016226//iron-sulfur cluster assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process;GO:0032364//oxygen homeostasis;GO:0002244//hematopoietic progenitor cell differentiation","GO:0046872//metal ion binding;GO:0051539//4 iron, 4 sulfur cluster binding",-
64429,0,1,0,31,10,0,0,0,48,0,0,0,"ZDHHC6;zinc finger, DHHC-type containing 6",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
6443,0,0,0,0,11,11,39,0,52,0,10,19,"SGCB;sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)",GO:0042383//sarcolemma;GO:0016012//sarcoglycan complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0048747//muscle fiber development;GO:0055013//cardiac muscle cell development;GO:0097084//vascular smooth muscle cell development;GO:0007517//muscle organ development,-,K12566//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy
64430,0,1,0,12,28,53,29,0,27,0,10,0,PCNXL4;pecanex-like 4 (Drosophila),GO:0016021//integral component of membrane,-,-,-
64431,0,39,0,5,42,0,0,5,17,0,0,0,ACTR6;ARP6 actin-related protein 6 homolog (yeast),GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
644316,0,0,0,0,0,0,31,0,26,0,0,0,FLJ43315;asparagine synthetase pseudogene,-,-,-,"K01953//Biosynthesis of secondary metabolites;Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments"
64432,88,0,10,41,48,0,0,0,59,0,28,0,MRPS25;mitochondrial ribosomal protein S25,GO:0005840//ribosome;GO:0005739//mitochondrion,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
64434,76,1,0,9,0,0,42,6,46,0,0,0,NOM1;nucleolar protein with MIF4G domain 1,GO:0005634//nucleus;GO:0005730//nucleolus,-,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
644353,0,0,0,0,0,0,24,0,9,0,0,0,"ZCCHC18;zinc finger, CCHC domain containing 18",-,-,GO:0003676//nucleic acid binding;GO:0008270//zinc ion binding,K04228//Vasopressin-regulated water reabsorption;Neuroactive ligand-receptor interaction
6444,176,21,0,10,9,42,45,0,24,0,1,0,"SGCD;sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)",GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016010//dystrophin-associated glycoprotein complex;GO:0042383//sarcolemma;GO:0005886//plasma membrane;GO:0016012//sarcoglycan complex;GO:0016021//integral component of membrane,GO:0007517//muscle organ development,-,K12563//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Dilated cardiomyopathy
644444,0,0,0,0,0,12,0,0,0,0,0,0,TMEM30C;transmembrane protein 30C,GO:0016021//integral component of membrane,-,-,-
64446,58,0,0,0,0,0,0,53,7,53,10,0,"DNAI2;dynein, axonemal, intermediate chain 2",GO:0005858//axonemal dynein complex;GO:0005874//microtubule;GO:0005930//axoneme,GO:0008152//metabolic process;GO:0042384//cilium assembly,GO:0003777//microtubule motor activity,K11143//Huntington's disease
6445,0,0,0,0,0,0,16,0,24,0,0,0,"SGCG;sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0042383//sarcolemma;GO:0016012//sarcoglycan complex;GO:0016021//integral component of membrane,GO:0007517//muscle organ development,GO:0005515//protein binding,K12564//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Viral myocarditis;Dilated cardiomyopathy
644524,0,0,0,0,0,0,0,0,0,0,4,0,NKX2-4;NK2 homeobox 4,GO:0005634//nucleus,"GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,-
644591,0,0,0,0,0,0,0,0,5,0,0,0,PPIAL4G;peptidylprolyl isomerase A (cyclophilin A)-like 4G,GO:0005737//cytoplasm,GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization,GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
644596,0,0,0,0,0,0,11,0,0,0,0,0,LINC00087;long intergenic non-protein coding RNA 87,-,-,-,-
6446,0,0,0,0,0,0,0,0,26,146,0,0,SGK1;serum/glucocorticoid regulated kinase 1,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050790//regulation of catalytic activity;GO:0030334//regulation of cell migration;GO:0070294//renal sodium ion absorption;GO:0006974//cellular response to DNA damage stimulus;GO:0006814//sodium ion transport;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0042127//regulation of cell proliferation;GO:0007616//long-term memory;GO:0042981//regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0034220//ion transmembrane transport;GO:0006915//apoptotic process;GO:0008217//regulation of blood pressure;GO:0032411//positive regulation of transporter activity;GO:0001558//regulation of cell growth;GO:0060453//regulation of gastric acid secretion;GO:0055085//transmembrane transport,GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0015459//potassium channel regulator activity;GO:0017080//sodium channel regulator activity;GO:0005524//ATP binding;GO:0005246//calcium channel regulator activity;GO:0017081//chloride channel regulator activity,K13302//Aldosterone-regulated sodium reabsorption
644619,145,41,56,2,22,23,35,2,42,125,15,0,INTS4L2;integrator complex subunit 4-like 2,-,-,-,-
644694,0,0,0,0,0,0,0,0,17,0,0,0,CDRT15P2;CMT1A duplicated region transcript 15 pseudogene 2,GO:0016021//integral component of membrane,-,-,-
6447,0,0,0,0,0,11,0,0,16,0,2,0,SCG5;secretogranin V (7B2 protein),GO:0005576//extracellular region;GO:0030141//secretory granule,GO:0046883//regulation of hormone secretion;GO:0006886//intracellular protein transport;GO:0043086//negative regulation of catalytic activity;GO:0007218//neuropeptide signaling pathway;GO:0016486//peptide hormone processing,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0004857//enzyme inhibitor activity;GO:0005525//GTP binding,-
644714,0,0,0,0,0,0,0,0,0,0,1,0,LIMD1-AS1;LIMD1 antisense RNA 1,-,-,-,-
644762,0,0,0,0,0,17,0,0,28,0,0,0,LOC644762;mitochondrial fission factor pseudogene,-,-,-,-
64478,9,0,0,0,0,70,40,62,90,136,21,347,CSMD1;CUB and Sushi multiple domains 1,GO:0016021//integral component of membrane,-,-,K14616//Vitamin digestion and absorption
6448,0,0,17,0,9,0,24,57,7,0,8,0,SGSH;N-sulfoglucosamine sulfohydrolase,GO:0070062//extracellular vesicular exosome;GO:0043202//lysosomal lumen,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006027//glycosaminoglycan catabolic process;GO:0006029//proteoglycan metabolic process;GO:0005975//carbohydrate metabolic process,GO:0016250//N-sulfoglucosamine sulfohydrolase activity;GO:0008484//sulfuric ester hydrolase activity;GO:0003824//catalytic activity;GO:0046872//metal ion binding,K01565//Metabolic pathways;Glycosaminoglycan degradation;Lysosome
644809,0,8,0,10,23,0,0,46,0,0,59,0,C15orf56;chromosome 15 open reading frame 56,-,-,-,-
644815,0,0,0,0,0,20,10,77,36,0,0,0,"FAM83G;family with sequence similarity 83, member G",GO:0005634//nucleus;GO:0005829//cytosol,GO:0030509//BMP signaling pathway,GO:0005515//protein binding,-
644861,86,0,0,0,0,0,0,0,14,0,0,0,"NBPF13P;neuroblastoma breakpoint family, member 13, pseudogene",-,-,-,-
644873,0,0,0,13,54,19,0,0,11,0,0,0,LINC01184;long intergenic non-protein coding RNA 1184,-,-,-,-
644890,0,0,0,0,0,0,0,0,24,0,0,0,MEIG1;meiosis/spermiogenesis associated 1,GO:0005634//nucleus,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
6449,11,16,0,2,11,0,0,52,36,129,0,117,"SGTA;small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha",GO:0005737//cytoplasm,GO:0016032//viral process,GO:0005515//protein binding,K09553//Prion diseases
644936,0,0,0,0,0,0,0,0,11,0,0,0,"LOC644936;actin, beta pseudogene",-,-,-,K05692//Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Focal adhesion;Vibrio cholerae infection;Gastric acid secretion;Pathogenic Escherichia coli infection;Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Viral myocarditis;Phototransduction - fly;Adherens junction;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A
644943,0,0,0,0,0,0,0,0,0,0,1,0,RASSF10;Ras association (RalGDS/AF-6) domain family (N-terminal) member 10,GO:0005829//cytosol;GO:0000922//spindle pole;GO:0005815//microtubule organizing center,GO:0007165//signal transduction,-,-
644945,88,0,0,0,0,0,0,0,15,0,2,0,KRT16P3;keratin 16 pseudogene 3,-,-,-,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
644962,0,0,0,0,0,0,0,0,0,0,4,0,TNRC18P1;TNRC18P1,-,-,-,-
644974,0,0,0,0,4,0,0,2,17,0,11,0,"ALG1L2;ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2",-,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",K03842//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
644994,0,0,0,0,0,0,0,0,4,0,11,0,SMIM23;small integral membrane protein 23,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
644997,10,0,0,0,0,0,20,0,8,0,0,0,C1orf200;chromosome 1 open reading frame 200,-,-,-,-
645,0,0,0,0,1,0,38,1,1,0,0,0,BLVRB;biliverdin reductase B (flavin reductase (NADPH)),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0006778//porphyrin-containing compound metabolic process;GO:0042167//heme catabolic process,GO:0004074//biliverdin reductase activity;GO:0042602//riboflavin reductase (NADPH) activity,K05901//Porphyrin and chlorophyll metabolism;Riboflavin metabolism
6450,0,0,0,0,9,6,0,0,0,0,0,0,SH3BGR;SH3 domain binding glutamate-rich protein,GO:0005829//cytosol,GO:0009967//positive regulation of signal transduction;GO:0006461//protein complex assembly,GO:0005070//SH3/SH2 adaptor activity;GO:0017124//SH3 domain binding,-
645027,0,0,0,14,0,1,0,0,28,0,0,250,EVPLL;envoplakin-like,-,-,-,-
64506,5,0,0,0,0,0,18,0,22,160,1,0,CPEB1;cytoplasmic polyadenylation element binding protein 1,GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0030054//cell junction,GO:0071230//cellular response to amino acid stimulus;GO:0032869//cellular response to insulin stimulus;GO:0006397//mRNA processing;GO:2000766//negative regulation of cytoplasmic translation;GO:0071456//cellular response to hypoxia,"GO:0000900//translation repressor activity, nucleic acid binding;GO:0046872//metal ion binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0000166//nucleotide binding",K02602//Progesterone-mediated oocyte maturation;Dorso-ventral axis formation;Oocyte meiosis
6451,0,0,0,33,29,0,0,0,38,0,0,0,SH3BGRL;SH3 domain binding glutamate-rich protein like,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0017124//SH3 domain binding,-
645104,0,0,0,0,0,0,0,37,0,0,1,0,CLRN2;clarin 2,GO:0016021//integral component of membrane,-,-,-
645121,0,0,0,12,1,0,0,0,14,232,13,0,"CCNI2;cyclin I family, member 2",-,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding,K10145//p53 signaling pathway;K10146//p53 signaling pathway
645166,30,0,0,0,0,38,20,83,3,0,10,481,LOC645166;lymphocyte-specific protein 1 pseudogene,-,-,-,K14957//Tuberculosis
64518,2,0,0,0,0,0,0,0,7,0,0,0,TEKT3;tektin 3,GO:0005874//microtubule;GO:0002080//acrosomal membrane;GO:0005634//nucleus;GO:0036126//sperm flagellum;GO:0070062//extracellular vesicular exosome,GO:0030317//sperm motility;GO:0080154//regulation of fertilization;GO:0060271//cilium morphogenesis,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K04688//TGF-beta signaling pathway;ErbB signaling pathway;Fc gamma R-mediated phagocytosis;mTOR signaling pathway;Acute myeloid leukemia;Insulin signaling pathway
645191,0,0,0,0,0,0,0,0,14,0,6,0,LINGO3;leucine rich repeat and Ig domain containing 3,GO:0016021//integral component of membrane,-,-,K07523//Axon guidance
6452,54,0,45,0,9,1,18,97,43,0,20,1,SH3BP2;SH3-domain binding protein 2,-,GO:0009967//positive regulation of signal transduction;GO:0007165//signal transduction,GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0005070//SH3/SH2 adaptor activity,K07984//Natural killer cell mediated cytotoxicity
645206,0,0,0,0,0,5,0,0,16,0,0,0,LINC00693;long intergenic non-protein coding RNA 693,-,-,-,-
6453,0,0,0,6,32,12,4,131,71,0,0,0,ITSN1;intersectin 1 (SH3 domain protein),GO:0005886//plasma membrane;GO:0045202//synapse;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005905//coated pit;GO:0030027//lamellipodium;GO:0030139//endocytic vesicle;GO:0005829//cytosol,GO:0048488//synaptic vesicle endocytosis;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0051897//positive regulation of protein kinase B signaling;GO:0032321//positive regulation of Rho GTPase activity;GO:0043524//negative regulation of neuron apoptotic process;GO:0043547//positive regulation of GTPase activity;GO:0042327//positive regulation of phosphorylation,GO:0005509//calcium ion binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0070064//proline-rich region binding;GO:0005515//protein binding;GO:0032947//protein complex scaffold;GO:0019209//kinase activator activity;GO:0005085//guanyl-nucleotide exchange factor activity,K13738//Bacterial invasion of epithelial cells
645339,28,0,0,0,0,13,0,0,0,0,0,0,SNRPD2P2;small nuclear ribonucleoprotein D2 pseudogene 2,-,-,-,K11096//Spliceosome
645367,0,0,0,0,11,0,14,0,29,0,0,0,GGT8P;gamma-glutamyltransferase 8 pseudogene,-,-,-,K00681//Metabolic pathways;Arachidonic acid metabolism;Cyanoamino acid metabolism;Glutathione metabolism;Taurine and hypotaurine metabolism
645369,0,0,0,0,0,0,0,0,31,0,0,0,TMEM200C;transmembrane protein 200C,GO:0016021//integral component of membrane,-,-,-
645402,0,0,1,0,0,17,0,1,0,0,0,0,USP17L4;ubiquitin specific peptidase 17-like family member 4,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0036459//ubiquitinyl hydrolase activity,-
645414,0,0,0,0,0,0,0,0,2,0,0,0,PRAMEF19;PRAME family member 19,-,"GO:0008284//positive regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process",GO:0042974//retinoic acid receptor binding,-
645425,0,0,0,0,0,7,0,0,0,0,0,0,PRAMEF20;PRAME family member 20,-,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0042974//retinoic acid receptor binding,-
645426,0,0,0,0,0,0,0,0,0,0,2,0,TMEM191C;transmembrane protein 191C,GO:0016021//integral component of membrane,-,-,-
645431,118,0,0,0,0,0,0,0,7,0,0,0,FUT8-AS1;FUT8 antisense RNA 1,-,-,-,-
645432,0,0,0,0,0,0,40,2,1,166,0,0,ARRDC5;arrestin domain containing 5,-,-,-,-
645455,0,0,0,0,0,0,0,0,1,0,0,0,CEP170P1;centrosomal protein 170kDa pseudogene 1,-,-,GO:0042802//identical protein binding,-
6455,0,24,0,1,36,34,11,126,51,0,26,0,SH3GL1;SH3-domain GRB2-like 1,GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0002102//podosome;GO:0030054//cell junction;GO:0031901//early endosome membrane,GO:0007165//signal transduction;GO:0007417//central nervous system development;GO:0006897//endocytosis,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0051020//GTPase binding;GO:0008289//lipid binding,K11247//Endocytosis
6456,0,32,0,0,0,12,32,0,0,0,0,0,SH3GL2;SH3-domain GRB2-like 2,GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0005829//cytosol,GO:0002090//regulation of receptor internalization;GO:0007165//signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0007411//axon guidance;GO:0061024//membrane organization;GO:0007417//central nervous system development;GO:0048488//synaptic vesicle endocytosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006892//post-Golgi vesicle-mediated transport,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008289//lipid binding,K11247//Endocytosis
645676,85,59,182,86,165,15,0,155,89,0,105,0,ASH1L-AS1;ASH1L antisense RNA 1,-,-,-,-
645682,0,0,0,0,0,0,0,0,8,0,0,0,POU5F1P4;POU class 5 homeobox 1 pseudogene 4,-,-,-,-
645683,0,0,0,0,0,13,44,2,26,0,0,0,RPL13AP3;ribosomal protein L13a pseudogene 3,GO:0070062//extracellular vesicular exosome;GO:0005840//ribosome;GO:0005634//nucleus,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K02872//Ribosome
645700,0,0,0,0,0,0,19,0,0,0,0,0,"ZNF890P;zinc finger protein 890, pseudogene",-,-,-,-
645745,0,0,0,0,0,0,0,0,11,0,0,0,MT1HL1;metallothionein 1H-like 1,-,-,GO:0046872//metal ion binding,-
645752,93,0,0,0,0,0,0,46,0,0,0,0,"LOC645752;golgin A6 family, member A pseudogene",-,-,-,K13517//Metabolic pathways;Glycerolipid metabolism;Glycerophospholipid metabolism;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;K12485//Endocytosis
64577,0,0,12,0,0,4,48,0,40,0,4,0,"ALDH8A1;aldehyde dehydrogenase 8 family, member A1",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,GO:0042574//retinal metabolic process;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0042573//retinoic acid metabolic process;GO:0055114//oxidation-reduction process,GO:0001758//retinal dehydrogenase activity,"K00128//Limonene and pinene degradation;Bacterial chemotaxis;Glycerolipid metabolism;beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Glycolysis / Gluconeogenesis;Arginine and proline metabolism;Lysine degradation;Fatty acid metabolism;Chloroalkane and chloroalkene degradation;Two-component system;Pyruvate metabolism;Propanoate metabolism;Pentose and glucuronate interconversions;Metabolic pathways;Biosynthesis of secondary metabolites;Tryptophan metabolism;Ascorbate and aldarate metabolism;Microbial metabolism in diverse environments;Histidine metabolism;K00149//beta-Alanine metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation;Propanoate metabolism;Pyruvate metabolism;Glycerolipid metabolism;Lysine degradation;Fatty acid metabolism;Arginine and proline metabolism;Histidine metabolism;Ascorbate and aldarate metabolism;Tryptophan metabolism;Glycolysis / Gluconeogenesis"
645784,0,0,0,4,0,0,0,0,0,0,5,0,ANKRD36BP2;ankyrin repeat domain 36B pseudogene 2,-,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
64579,0,0,0,0,0,0,0,0,41,0,0,0,NDST4;N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0030210//heparin biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity;GO:0019213//deacetylase activity,K02579//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
6458,0,0,0,0,0,0,0,0,15,0,0,0,SH3GL1P1;SH3-domain GRB2-like 1 pseudogene 1,-,-,-,K11247//Endocytosis
645811,0,117,218,129,520,0,12,863,144,0,868,0,CCDC154;coiled-coil domain containing 154,GO:0005769//early endosome,-,-,K06102//Tight junction;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
64582,0,0,0,0,0,0,0,0,0,249,0,0,GPR135;G protein-coupled receptor 135,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
645832,0,0,0,7,15,0,0,0,0,0,0,0,SEBOX;SEBOX homeobox,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003677//DNA binding,K09381//Transcriptional misregulation in cancer
645836,0,0,0,0,0,0,0,0,5,0,1,3,USP17L3;ubiquitin specific peptidase 17-like family member 3,GO:0005783//endoplasmic reticulum;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process,GO:0008234//cysteine-type peptidase activity;GO:0036459//ubiquitinyl hydrolase activity,-
645840,0,0,0,0,0,23,32,0,0,0,0,0,TXNRD3NB;thioredoxin reductase 3 neighbor,-,-,-,K00384//Selenocompound metabolism;Pyrimidine metabolism;Two-component system
645843,0,0,0,0,0,0,0,0,25,0,0,0,TMEM14E;transmembrane protein 14E,GO:0016021//integral component of membrane,-,-,-
645864,0,0,0,0,9,0,0,0,0,0,0,0,"MAGEB17;melanoma antigen family B, 17",-,-,-,K12464//Neurotrophin signaling pathway
6459,16,0,2,0,0,0,0,0,17,0,5,0,SH3GL1P2;SH3-domain GRB2-like 1 pseudogene 2,-,-,-,K11247//Endocytosis
64591,0,0,0,0,0,0,0,0,0,1,0,0,"TSPY2;testis specific protein, Y-linked 2",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation;GO:0006334//nucleosome assembly,-,-
645922,0,0,0,0,0,0,0,0,7,0,0,0,S100A7L2;S100 calcium binding protein A7-like 2,-,-,GO:0005509//calcium ion binding,-
645954,0,0,0,0,0,0,0,45,18,0,11,0,SVILP1;supervillin pseudogene 1,-,-,-,-
645958,0,0,0,0,0,0,0,0,2,0,0,0,RPS18P9;ribosomal protein S18 pseudogene 9,-,-,-,K02964//Ribosome
645961,0,0,0,0,0,1,14,0,9,3,2,0,"SPATA31C2;SPATA31 subfamily C, member 2",-,-,-,-
645974,0,0,0,1,1,0,0,0,31,0,1,0,"PABPC1L2B;poly(A) binding protein, cytoplasmic 1-like 2B",GO:0070062//extracellular vesicular exosome,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K13126//mRNA surveillance pathway;RNA transport;RNA degradation
64598,1,0,0,0,0,0,0,1,0,0,0,0,MOSPD3;motile sperm domain containing 3,GO:0016021//integral component of membrane,GO:0007507//heart development,GO:0005198//structural molecule activity,-
64599,0,0,0,0,11,25,0,73,62,0,0,0,GIGYF1;GRB10 interacting GYF protein 1,-,GO:0048009//insulin-like growth factor receptor signaling pathway,-,-
645996,0,0,0,0,0,0,0,0,12,0,0,0,NAP1L6;nucleosome assembly protein 1-like 6,GO:0005634//nucleus,GO:0006334//nucleosome assembly,-,-
64600,0,0,0,0,0,0,0,133,1,0,10,1,"PLA2G2F;phospholipase A2, group IIF",GO:0005576//extracellular region;GO:0005829//cytosol,GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process,GO:0004623//phospholipase A2 activity;GO:0005509//calcium ion binding,K01047//Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Glycerophospholipid metabolism;Ether lipid metabolism;VEGF signaling pathway;GnRH signaling pathway;Serotonergic synapse;Pancreatic secretion;alpha-Linolenic acid metabolism;Glutamatergic synapse;Linoleic acid metabolism;MAPK signaling pathway;Vascular smooth muscle contraction;Metabolic pathways
646000,0,0,0,0,0,0,0,0,7,0,0,0,"SLC35G4P;solute carrier family 35, member G4, pseudogene",GO:0016021//integral component of membrane,-,-,-
64601,101,0,0,0,1,0,0,63,23,53,8,0,VPS16;vacuolar protein sorting 16 homolog (S. cerevisiae),GO:0043025//neuronal cell body;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0005770//late endosome;GO:0005769//early endosome;GO:0055037//recycling endosome;GO:0005884//actin filament;GO:0031902//late endosome membrane;GO:0030424//axon,GO:0046718//viral entry into host cell;GO:0006886//intracellular protein transport,GO:0051015//actin filament binding,-
646019,0,0,41,0,0,0,0,358,14,0,52,0,CBY3;chibby homolog 3 (Drosophila),-,-,-,-
646074,0,1,0,0,1,28,23,46,33,0,11,0,"POM121L10P;POM121 transmembrane nucleoporin-like 10, pseudogene",-,-,-,K14316//RNA transport
646096,0,0,0,0,0,25,0,0,45,0,12,0,CHEK2P2;checkpoint kinase 2 pseudogene 2,-,-,-,K06641//HTLV-I infection;p53 signaling pathway;Cell cycle - yeast;Cell cycle
6461,0,0,0,0,15,26,0,35,48,0,78,0,SHB;Src homology 2 domain containing adaptor protein B,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0006915//apoptotic process;GO:0001525//angiogenesis;GO:0009967//positive regulation of signal transduction;GO:0007165//signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07365//T cell receptor signaling pathway;Axon guidance;Pathogenic Escherichia coli infection;ErbB signaling pathway;K08887//ErbB signaling pathway;Viral myocarditis;K06619//Axon guidance;Pathways in cancer;Shigellosis;Viral myocarditis;Chronic myeloid leukemia;Neurotrophin signaling pathway;ErbB signaling pathway;Pathogenic Escherichia coli infection;Cell cycle
646113,0,0,0,0,0,0,44,0,35,0,12,0,LINC00643;long intergenic non-protein coding RNA 643,-,-,-,-
646174,7,0,0,0,0,13,1,0,0,0,0,0,C16orf90;chromosome 16 open reading frame 90,-,-,-,-
6462,0,0,0,0,0,7,0,0,27,0,0,0,SHBG;sex hormone-binding globulin,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0007285//primary spermatocyte growth,GO:0005497//androgen binding,K03908//Complement and coagulation cascades
646201,0,0,0,0,0,0,0,0,11,0,0,0,"BASP1P1;brain abundant, membrane attached signal protein 1 pseudogene 1",-,-,-,-
646214,0,0,0,0,1,51,277,4,174,0,45,470,LOC646214;p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene,-,-,-,K04410//ErbB signaling pathway;Focal adhesion;Renal cell carcinoma;MAPK signaling pathway;Axon guidance;T cell receptor signaling pathway;Regulation of actin cytoskeleton
646262,0,0,0,0,0,0,29,0,12,0,6,327,"LACTBL1;lactamase, beta-like 1",-,-,-,-
646278,0,0,0,0,0,11,0,39,19,0,0,0,PDCD6IPP2;PDCD6IP pseudogene 2,-,-,-,K12200//Endocytosis
646282,0,0,0,0,1,0,0,50,31,0,0,0,"AZGP1P1;alpha-2-glycoprotein 1, zinc-binding pseudogene 1",-,-,-,K06751//Antigen processing and presentation;Epstein-Barr virus infection;Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Herpes simplex infection;Viral myocarditis;Graft-versus-host disease;Allograft rejection;Type I diabetes mellitus;HTLV-I infection;Endocytosis;Phagosome;Autoimmune thyroid disease
646300,0,0,0,0,0,36,48,0,23,0,0,0,"COL6A4P2;collagen, type VI, alpha 4 pseudogene 2",-,-,-,K06238//ECM-receptor interaction;Focal adhesion;Protein digestion and absorption
646396,17,0,0,0,0,0,0,0,50,0,0,0,REREP3;arginine-glutamic acid dipeptide (RE) repeats pseudogene 3,-,-,-,-
6464,76,34,0,44,116,0,0,60,25,0,13,0,SHC1;SHC (Src homology 2 domain containing) transforming protein 1,GO:0005759//mitochondrial matrix;GO:0070435//Shc-EGFR complex;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007507//heart development;GO:0001525//angiogenesis;GO:0007265//Ras protein signal transduction;GO:0040008//regulation of growth;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0031532//actin cytoskeleton reorganization;GO:0016337//single organismal cell-cell adhesion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0050900//leukocyte migration;GO:0030168//platelet activation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0045740//positive regulation of DNA replication;GO:0007596//blood coagulation;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0044267//cellular protein metabolic process,GO:0005154//epidermal growth factor receptor binding;GO:0004713//protein tyrosine kinase activity;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005543//phospholipid binding;GO:0005168//neurotrophin TRKA receptor binding;GO:0005515//protein binding;GO:0046875//ephrin receptor binding;GO:0005158//insulin receptor binding;GO:0005159//insulin-like growth factor receptor binding,K06279//Insulin signaling pathway;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Alcoholism;Neurotrophin signaling pathway;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;Focal adhesion;VEGF signaling pathway;Glioma;ErbB signaling pathway
64641,0,0,0,0,0,6,35,0,19,0,8,0,EBF2;early B-cell factor 2,GO:0005634//nucleus,"GO:0050873//brown fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0001709//cell fate determination;GO:0060612//adipose tissue development;GO:0035563//positive regulation of chromatin binding",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding,-
64645,0,55,0,0,15,0,20,0,28,0,1,0,HIAT1;hippocampus abundant transcript 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport,GO:0005215//transporter activity,K14613//Mineral absorption;Vitamin digestion and absorption
646450,82,137,1,114,176,0,34,0,49,0,86,0,ARIH2OS;ariadne homolog 2 opposite strand,GO:0016021//integral component of membrane,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
646457,74,0,0,0,0,0,32,0,49,0,0,2,C19orf67;chromosome 19 open reading frame 67,-,-,-,-
646471,0,649,623,566,1205,11,7,573,63,1,678,645,LOC646471;uncharacterized LOC646471,-,-,-,K06264//ECM-receptor interaction;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
64648,0,0,0,0,0,0,0,0,24,2,0,0,"SPANXD;SPANX family, member D",GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
646480,0,0,0,0,0,0,0,0,21,0,0,0,"FABP9;fatty acid binding protein 9, testis",GO:0001669//acrosomal vesicle,GO:0006810//transport;GO:0001675//acrosome assembly,GO:0005215//transporter activity;GO:0008289//lipid binding,K08753//PPAR signaling pathway
646498,0,0,0,0,0,0,0,0,14,0,0,0,C3orf84;chromosome 3 open reading frame 84,-,-,-,-
646508,0,0,0,0,0,0,0,0,3,0,0,0,"FAM90A27P;family with sequence similarity 90, member A27, pseudogene",-,-,-,-
64651,0,0,33,19,29,0,0,186,55,0,7,0,CSRNP1;cysteine-serine-rich nuclear protein 1,GO:0005634//nucleus,"GO:0009791//post-embryonic development;GO:0048705//skeletal system morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060325//face morphogenesis;GO:0060021//palate development;GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0048008//platelet-derived growth factor receptor signaling pathway",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
646603,9,0,0,0,0,0,0,0,0,0,0,0,C4orf51;chromosome 4 open reading frame 51,-,-,-,-
646625,238,0,37,0,0,0,0,0,1,58,0,0,URAD;ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase,GO:0005777//peroxisome,GO:0019628//urate catabolic process;GO:0019428//allantoin biosynthetic process;GO:0006144//purine nucleobase metabolic process,GO:0016831//carboxy-lyase activity,K13485//Purine metabolism;Metabolic pathways
646643,0,0,0,0,0,0,7,0,0,0,0,0,"SBK2;SH3 domain binding kinase family, member 2",-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
646658,0,0,0,0,0,0,22,0,13,0,0,0,SYNDIG1L;synapse differentiation inducing 1-like,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0009607//response to biotic stimulus,-,-
646743,0,0,0,0,0,0,0,0,1,0,0,0,LOC646743;uncharacterized LOC646743,-,-,-,-
646762,0,0,0,0,0,22,43,0,23,0,0,0,LOC646762;uncharacterized LOC646762,-,-,-,K11447//Transcriptional misregulation in cancer
646799,0,0,0,0,0,0,40,0,10,0,0,0,ZAR1L;zygote arrest 1-like,GO:0005737//cytoplasm,-,-,-
6468,0,0,0,0,28,35,26,0,31,0,0,0,FBXW4;F-box and WD repeat domain containing 4,GO:0000151//ubiquitin ligase complex,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0042733//embryonic digit morphogenesis;GO:0030326//embryonic limb morphogenesis;GO:0051216//cartilage development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0016055//Wnt signaling pathway,-,-
646817,0,0,0,0,0,0,0,0,0,0,0,301,SETSIP;SET-like protein,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045446//endothelial cell differentiation;GO:0006334//nucleosome assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding,-
64682,4,28,0,11,59,61,30,0,164,26,17,0,ANAPC1;anaphase promoting complex subunit 1,GO:0005654//nucleoplasm;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol,GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division,-,K03348//Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle;Oocyte meiosis;HTLV-I infection;Meiosis - yeast
646851,0,0,0,2,0,3,71,9,53,0,8,0,"FAM227A;family with sequence similarity 227, member A",-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
646862,0,0,0,0,0,0,0,0,0,1,0,0,LOC646862;uncharacterized LOC646862,-,-,-,K14683//Mineral absorption
64689,0,0,0,105,55,18,42,3,9,0,41,0,"GORASP1;golgi reassembly stacking protein 1, 65kDa",GO:0000139//Golgi membrane,GO:0015031//protein transport;GO:0007030//Golgi organization;GO:0000278//mitotic cell cycle;GO:0050774//negative regulation of dendrite morphogenesis,-,-
646892,0,21,0,0,15,0,1,136,39,0,24,0,SH2D7;SH2 domain containing 7,-,-,-,K08273//VEGF signaling pathway
64693,0,0,0,0,0,15,0,0,43,0,0,0,CTAGE1;cutaneous T-cell lymphoma-associated antigen 1,GO:0016021//integral component of membrane,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
646960,0,0,0,0,0,8,0,0,41,0,0,0,"PRSS56;protease, serine, 56",GO:0005783//endoplasmic reticulum,GO:0006508//proteolysis;GO:0043010//camera-type eye development,GO:0004252//serine-type endopeptidase activity,-
646962,0,0,0,0,20,0,0,0,0,0,8,0,HRCT1;histidine rich carboxyl terminus 1,GO:0016021//integral component of membrane,-,-,-
64699,0,25,0,0,0,0,0,0,80,0,0,0,"TMPRSS3;transmembrane protease, serine 3",GO:0005789//endoplasmic reticulum membrane;GO:0043025//neuronal cell body;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0006883//cellular sodium ion homeostasis;GO:0007605//sensory perception of sound;GO:0006898//receptor-mediated endocytosis;GO:0006508//proteolysis,GO:0017080//sodium channel regulator activity;GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity,-
6470,0,0,0,44,15,15,0,0,8,0,14,0,SHMT1;serine hydroxymethyltransferase 1 (soluble),GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051262//protein tetramerization;GO:0045329//carnitine biosynthetic process;GO:0006766//vitamin metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0051289//protein homotetramerization;GO:0019264//glycine biosynthetic process from serine;GO:0035999//tetrahydrofolate interconversion;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006565//L-serine catabolic process;GO:0046655//folic acid metabolic process,GO:0042803//protein homodimerization activity;GO:0008732//L-allo-threonine aldolase activity;GO:0016597//amino acid binding;GO:0004372//glycine hydroxymethyltransferase activity;GO:0030170//pyridoxal phosphate binding,"K00600//Metabolic pathways;ABC transporters;Glyoxylate and dicarboxylate metabolism;Fatty acid biosynthesis;One carbon pool by folate;Microbial metabolism in diverse environments;Cyanoamino acid metabolism;Glycine, serine and threonine metabolism;Methane metabolism;Biosynthesis of secondary metabolites"
647024,0,22,0,5,19,16,14,0,28,50,14,0,C6orf132;chromosome 6 open reading frame 132,-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
647033,0,0,0,0,0,0,21,0,9,0,0,0,PA2G4P4;proliferation-associated 2G4 pseudogene 4,-,-,-,K05084//Calcium signaling pathway;ErbB signaling pathway;Endocytosis
647042,0,0,0,0,0,0,1,0,1,0,1,0,GOLGA6L10;golgin A6 family-like 10,-,-,-,-
647060,0,0,0,0,0,0,0,0,3,0,1,0,"SPATA31A1;SPATA31 subfamily A, member 1",GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
64708,0,0,17,6,16,0,0,0,13,0,5,0,COPS7B;COP9 signalosome subunit 7B,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0008180//COP9 signalosome,GO:0010388//cullin deneddylation,-,-
647087,0,1,0,50,51,17,3,0,16,0,0,0,C7orf73;chromosome 7 open reading frame 73,GO:0005576//extracellular region,-,-,-
64710,64,236,2,344,1226,12,17,1,1,0,0,260,NUCKS1;nuclear casein kinase and cyclin-dependent kinase substrate 1,GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,-
64711,0,0,0,0,0,0,1,0,0,0,0,0,HS3ST6;heparan sulfate (glucosamine) 3-O-sulfotransferase 6,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process,GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity,-
647121,0,0,0,0,0,10,0,0,14,0,0,0,EMBP1;embigin pseudogene 1,-,-,-,-
647135,0,11,0,0,0,0,67,0,22,0,0,0,SRGAP2B;SLIT-ROBO Rho GTPase activating protein 2B,-,-,-,K07526//Axon guidance
64714,0,0,0,0,0,15,0,40,0,150,0,0,"PDIA2;protein disulfide isomerase family A, member 2",GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen,GO:0006621//protein retention in ER lumen;GO:0006457//protein folding;GO:0034976//response to endoplasmic reticulum stress;GO:0019511//peptidyl-proline hydroxylation;GO:0045454//cell redox homeostasis;GO:1902175//regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,GO:0031545//peptidyl-proline 4-dioxygenase activity;GO:0005496//steroid binding;GO:0003756//protein disulfide isomerase activity;GO:0005515//protein binding,-
647166,0,0,0,0,0,0,0,0,63,1,0,194,LINC00371;long intergenic non-protein coding RNA 371,-,-,-,K12319//Gap junction;Vascular smooth muscle contraction;Long-term depression;Salivary secretion;Purine metabolism
647174,55,0,0,35,0,0,75,0,5,0,46,0,"SERPINE3;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3",GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity,K03982//Chagas disease (American trypanosomiasis);Complement and coagulation cascades;p53 signaling pathway
64718,0,0,0,0,1,11,0,68,30,13,16,0,UNKL;unkempt family zinc finger-like,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
647190,0,0,0,0,0,0,8,0,0,0,0,0,RPS16P5;ribosomal protein S16 pseudogene 5,-,-,-,K02960//Ribosome
6472,0,0,0,1,11,0,0,0,25,0,5,0,SHMT2;serine hydroxymethyltransferase 2 (mitochondrial),GO:0015630//microtubule cytoskeleton;GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular vesicular exosome;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane,GO:0006730//one-carbon metabolic process;GO:0051289//protein homotetramerization;GO:0008284//positive regulation of cell proliferation;GO:0006564//L-serine biosynthetic process;GO:0035999//tetrahydrofolate interconversion;GO:0019264//glycine biosynthetic process from serine,GO:0016597//amino acid binding;GO:0004372//glycine hydroxymethyltransferase activity;GO:0003682//chromatin binding;GO:0030170//pyridoxal phosphate binding;GO:0042802//identical protein binding;GO:0008732//L-allo-threonine aldolase activity,"K00600//Fatty acid biosynthesis;ABC transporters;Metabolic pathways;Glyoxylate and dicarboxylate metabolism;Glycine, serine and threonine metabolism;Cyanoamino acid metabolism;Biosynthesis of secondary metabolites;Methane metabolism;One carbon pool by folate;Microbial metabolism in diverse environments"
647219,0,0,0,0,0,0,0,0,43,0,0,0,ASCL5;achaete-scute family bHLH transcription factor 5,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
647286,0,0,0,0,0,0,0,0,16,0,0,0,RD3L;retinal degeneration 3-like,-,-,-,-
647288,0,0,0,0,0,1,0,0,17,0,0,0,"CTAGE11P;CTAGE family, member 11, pseudogene",-,-,-,-
6473,0,0,0,0,0,0,33,0,37,7,16,0,SHOX;short stature homeobox,GO:0005634//nucleus,"GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
647309,0,0,0,0,0,0,0,0,0,0,10,0,GMNC;geminin coiled-coil domain containing,GO:0005634//nucleus,GO:0006270//DNA replication initiation;GO:0008283//cell proliferation;GO:0007049//cell cycle,GO:0003682//chromatin binding,-
647310,189,0,0,0,0,0,0,104,8,0,1,0,TEX22;testis expressed 22,GO:0001669//acrosomal vesicle,-,-,-
6474,0,0,0,0,0,0,13,0,0,0,12,0,SHOX2;short stature homeobox 2,GO:0005634//nucleus,GO:0003209//cardiac atrium morphogenesis;GO:0048557//embryonic digestive tract morphogenesis;GO:0007507//heart development;GO:0048743//positive regulation of skeletal muscle fiber development;GO:0003170//heart valve development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060415//muscle tissue morphogenesis;GO:0032330//regulation of chondrocyte differentiation;GO:0060351//cartilage development involved in endochondral bone morphogenesis;GO:0001649//osteoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050772//positive regulation of axonogenesis;GO:2000172//regulation of branching morphogenesis of a nerve;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007399//nervous system development;GO:0002063//chondrocyte development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0001501//skeletal system development;GO:0035115//embryonic forelimb morphogenesis,GO:0043565//sequence-specific DNA binding,-
64743,31,0,0,0,19,26,0,0,10,0,0,0,WDR13;WD repeat domain 13,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
64744,0,1,4,2,14,13,0,0,50,0,0,0,SMAP2;small ArfGAP2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12486//Endocytosis
64745,0,0,0,0,0,32,31,0,9,0,0,0,METTL17;methyltransferase like 17,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0032259//methylation;GO:0006412//translation,GO:0005515//protein binding;GO:0008168//methyltransferase activity;GO:0005507//copper ion binding,-
64746,0,99,2,66,80,0,0,44,21,0,0,0,ACBD3;acyl-CoA binding domain containing 3,GO:0005794//Golgi apparatus;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane,GO:0006694//steroid biosynthetic process;GO:0006810//transport,GO:0000062//fatty-acyl-CoA binding;GO:0005515//protein binding,-
64747,0,0,1,1,40,6,0,0,12,0,0,0,MFSD1;major facilitator superfamily domain containing 1,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
647476,0,0,0,0,0,0,3,0,0,0,0,0,"FLJ20518;FSHD region gene 2 family, member C pseudogene",-,-,-,K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K11447//Transcriptional misregulation in cancer;K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
64748,13,0,0,0,10,0,43,0,47,5,0,0,LPPR2;lipid phosphate phosphatase-related protein type 2,GO:0016021//integral component of membrane,GO:0016311//dephosphorylation,GO:0008195//phosphatidate phosphatase activity,K01080//Glycerophospholipid metabolism;Fc gamma R-mediated phagocytosis;Ether lipid metabolism;Sphingolipid metabolism;Glycerolipid metabolism;Fat digestion and absorption;Metabolic pathways
64750,0,1,0,38,70,46,0,0,26,0,1,0,SMURF2;SMAD specific E3 ubiquitin protein ligase 2,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0005654//nucleoplasm,"GO:0030509//BMP signaling pathway;GO:0010467//gene expression;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process",GO:0042802//identical protein binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005160//transforming growth factor beta receptor binding;GO:0046332//SMAD binding,K04678//TGF-beta signaling pathway;Ubiquitin mediated proteolysis;Endocytosis
64753,0,0,0,0,28,0,12,0,71,0,17,1,CCDC136;coiled-coil domain containing 136,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,-
64754,0,0,0,0,2,0,0,0,13,0,0,0,SMYD3;SET and MYND domain containing 3,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071549//cellular response to dexamethasone stimulus;GO:0045184//establishment of protein localization;GO:0014904//myotube cell development;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0034968//histone lysine methylation;GO:0006334//nucleosome assembly;GO:0006469//negative regulation of protein kinase activity,GO:0046872//metal ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000993//RNA polymerase II core binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0001162//RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding,-
64755,0,2,0,1,0,0,1,376,74,1,0,1,C16orf58;chromosome 16 open reading frame 58,GO:0016021//integral component of membrane;GO:0016020//membrane,-,-,-
64756,0,0,0,25,48,0,0,0,50,0,0,0,ATPAF1;ATP synthase mitochondrial F1 complex assembly factor 1,GO:0005739//mitochondrion,GO:0006461//protein complex assembly,GO:0005515//protein binding,-
64757,0,28,0,0,12,0,0,0,11,120,0,1,MARC1;mitochondrial amidoxime reducing component 1,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane,GO:0051410//detoxification of nitrogen compound;GO:0055114//oxidation-reduction process;GO:0042126//nitrate metabolic process,GO:0030170//pyridoxal phosphate binding;GO:0008940//nitrate reductase activity;GO:0030151//molybdenum ion binding;GO:0043546//molybdopterin cofactor binding,-
647589,0,0,0,0,0,13,15,0,33,0,0,0,ANHX;anomalous homeobox,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K15614//Transcriptional misregulation in cancer
64759,0,0,0,3,0,0,31,0,174,155,0,1,TNS3;tensin 3,GO:0005925//focal adhesion;GO:0005737//cytoplasm,GO:0048286//lung alveolus development;GO:0016477//cell migration;GO:0008284//positive regulation of cell proliferation,GO:0005515//protein binding,K01110//Prostate cancer;Small cell lung cancer;Phosphatidylinositol signaling system;Pathways in cancer;Tight junction;p53 signaling pathway;Glioma;Inositol phosphate metabolism;Focal adhesion;Endometrial cancer;Melanoma;K00665//Fatty acid biosynthesis;Insulin signaling pathway;Metabolic pathways
6476,1,0,0,0,0,0,13,0,102,0,0,0,SI;sucrase-isomaltase (alpha-glucosidase),GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0005903//brush border,GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044245//polysaccharide digestion,"GO:0004575//sucrose alpha-glucosidase activity;GO:0030246//carbohydrate binding;GO:0004574//oligo-1,6-glucosidase activity",K01203//Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism;Carbohydrate digestion and absorption
64760,49,0,0,18,27,20,68,73,37,0,50,0,"FAM160B2;family with sequence similarity 160, member B2",-,-,-,-
64761,0,17,9,20,12,0,0,121,22,95,1,2,"PARP12;poly (ADP-ribose) polymerase family, member 12",GO:0005634//nucleus,GO:0008152//metabolic process,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
64762,0,0,1,14,65,0,0,0,27,232,0,0,"GAREM;GRB2 associated, regulator of MAPK1",GO:0005886//plasma membrane,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0051781//positive regulation of cell division;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0008284//positive regulation of cell proliferation,GO:0070064//proline-rich region binding;GO:0005515//protein binding,K04574//Amyotrophic lateral sclerosis (ALS)
64763,0,0,0,8,0,18,0,0,12,0,0,0,ZNF574;zinc finger protein 574,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
64764,134,1,0,18,100,14,24,0,18,0,0,1,CREB3L2;cAMP responsive element binding protein 3-like 2,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,"GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051216//cartilage development;GO:0034976//response to endoplasmic reticulum stress;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein;GO:0045893//positive regulation of transcription, DNA-templated;GO:0002062//chondrocyte differentiation;GO:0006351//transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0035497//cAMP response element binding,K09048//Amphetamine addiction;Vasopressin-regulated water reabsorption;Melanogenesis;Cocaine addiction;Dopaminergic synapse;Cholinergic synapse;Huntington's disease;Alcoholism;Prostate cancer
64766,0,0,0,15,18,0,35,0,18,0,11,0,S100PBP;S100P binding protein,GO:0005634//nucleus,-,GO:0048306//calcium-dependent protein binding,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
64768,0,14,0,15,22,22,0,1,17,200,29,0,"IPPK;inositol 1,3,4,5,6-pentakisphosphate 2-kinase",GO:0005829//cytosol;GO:0005622//intracellular;GO:0005654//nucleoplasm,GO:0052746//inositol phosphorylation;GO:0044281//small molecule metabolic process;GO:0043647//inositol phosphate metabolic process,GO:0035299//inositol pentakisphosphate 2-kinase activity;GO:0005524//ATP binding,K10572//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
64769,0,167,0,105,273,2,8,0,28,0,0,0,MEAF6;MYST/Esa1-associated factor 6,GO:0070776//MOZ/MORF histone acetyltransferase complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0035267//NuA4 histone acetyltransferase complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0044154//histone H3-K14 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0043984//histone H4-K16 acetylation;GO:0043982//histone H4-K8 acetylation;GO:0006325//chromatin organization;GO:0043968//histone H2A acetylation;GO:0043981//histone H4-K5 acetylation;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
6477,0,48,0,47,176,26,0,0,54,0,0,0,SIAH1;siah E3 ubiquitin protein ligase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030877//beta-catenin destruction complex;GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0030163//protein catabolic process;GO:0009653//anatomical structure morphogenesis;GO:0006915//apoptotic process;GO:0051402//neuron apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0031648//protein destabilization;GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0043065//positive regulation of apoptotic process,GO:0008022//protein C-terminus binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,K04506//Wnt signaling pathway;Ubiquitin mediated proteolysis;p53 signaling pathway
64770,0,1,0,13,22,0,18,0,0,94,0,0,CCDC14;coiled-coil domain containing 14,GO:0005813//centrosome,GO:0021762//substantia nigra development,-,K04257//Olfactory transduction
64771,0,29,0,94,178,14,17,37,32,0,7,0,C6orf106;chromosome 6 open reading frame 106,-,-,-,-
64772,0,0,0,0,0,1,58,0,14,85,0,0,ENGASE;endo-beta-N-acetylglucosaminidase,GO:0005829//cytosol,GO:0008152//metabolic process,GO:0033925//mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity,K01227//Other glycan degradation
64773,0,0,0,0,0,8,0,34,0,26,0,0,PCED1A;PC-esterase domain containing 1A,-,-,-,-
64776,0,0,0,29,46,2,0,0,31,0,0,488,C11orf1;chromosome 11 open reading frame 1,GO:0005634//nucleus,-,-,-
64777,0,0,0,29,5,14,0,76,34,0,0,0,RMND5B;required for meiotic nuclear division 5 homolog B (S. cerevisiae),-,-,-,-
64778,61,37,0,8,87,36,38,67,46,7,0,0,FNDC3B;fibronectin type III domain containing 3B,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0045668//negative regulation of osteoblast differentiation;GO:0016477//cell migration;GO:0060510//Type II pneumocyte differentiation;GO:0048146//positive regulation of fibroblast proliferation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0045600//positive regulation of fat cell differentiation,GO:0044822//poly(A) RNA binding,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
64779,0,0,0,0,20,9,0,44,53,0,7,0,MTHFSD;methenyltetrahydrofolate synthetase domain containing,-,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K01934//One carbon pool by folate;Metabolic pathways;Nucleotide excision repair
6478,0,1,0,7,54,0,0,41,34,0,119,0,SIAH2;siah E3 ubiquitin protein ligase 2,GO:0005769//early endosome;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body,GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0007049//cell cycle;GO:0031396//regulation of protein ubiquitination;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0007411//axon guidance;GO:0016567//protein ubiquitination;GO:2001141//regulation of RNA biosynthetic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0044257//cellular protein catabolic process,GO:0031624//ubiquitin conjugating enzyme binding;GO:0003714//transcription corepressor activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
64780,106,0,0,0,0,0,0,0,14,3,0,291,"MICAL1;microtubule associated monooxygenase, calponin and LIM domain containing 1",GO:0005737//cytoplasm;GO:0005882//intermediate filament,GO:0043066//negative regulation of apoptotic process;GO:0019417//sulfur oxidation;GO:0007010//cytoskeleton organization;GO:0055114//oxidation-reduction process;GO:0030042//actin filament depolymerization;GO:0001933//negative regulation of protein phosphorylation;GO:0007165//signal transduction;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,"GO:0008270//zinc ion binding;GO:0017124//SH3 domain binding;GO:0071949//FAD binding;GO:0005515//protein binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0017137//Rab GTPase binding;GO:0003779//actin binding",K05699//Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Focal adhesion;Amoebiasis;Adherens junction;Regulation of actin cytoskeleton;Systemic lupus erythematosus;K06115//Tight junction
64781,58,0,0,0,0,18,12,74,78,0,0,0,CERK;ceramide kinase,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006672//ceramide metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0006665//sphingolipid metabolic process;GO:0046834//lipid phosphorylation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0005524//ATP binding;GO:0001729//ceramide kinase activity;GO:0000287//magnesium ion binding;GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity,K04715//Sphingolipid metabolism
64782,0,0,0,0,0,0,0,0,47,0,1,0,AEN;apoptosis enhancing nuclease,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane,GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0010212//response to ionizing radiation;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,GO:0004527//exonuclease activity;GO:0003676//nucleic acid binding,-
64783,0,0,0,0,3,21,0,4,11,0,0,3,RBM15;RNA binding motif protein 15,GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0060674//placenta blood vessel development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007221//positive regulation of transcription of Notch receptor target;GO:0060412//ventricular septum morphogenesis;GO:0016032//viral process;GO:0045638//negative regulation of myeloid cell differentiation;GO:0001569//patterning of blood vessels;GO:0048536//spleen development",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
64784,0,0,0,0,15,6,0,0,15,0,15,0,CRTC3;CREB regulated transcription coactivator 3,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0050995//negative regulation of lipid catabolic process;GO:0032793//positive regulation of CREB transcription factor activity;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0016032//viral process;GO:0051289//protein homotetramerization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0097009//energy homeostasis",GO:0008140//cAMP response element binding protein binding,K15309//HTLV-I infection
64785,0,0,0,11,0,0,0,3,20,0,17,0,GINS3;GINS complex subunit 3 (Psf3 homolog),GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006260//DNA replication,-,-
64786,0,18,1,58,123,0,15,0,52,0,23,0,"TBC1D15;TBC1 domain family, member 15",GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity;GO:0032313//regulation of Rab GTPase activity,GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K13136//RNA transport;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
64787,53,2,0,0,24,0,0,68,11,0,7,0,EPS8L2;EPS8-like 2,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0032587//ruffle membrane;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0043234//protein complex,GO:0035023//regulation of Rho protein signal transduction;GO:0007266//Rho protein signal transduction;GO:1900029//positive regulation of ruffle assembly;GO:0032855//positive regulation of Rac GTPase activity;GO:0032321//positive regulation of Rho GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0003779//actin binding,K07370//B cell receptor signaling pathway;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Osteoclast differentiation;Primary immunodeficiency
64788,5,19,0,7,0,0,13,0,27,0,0,0,LMF1;lipase maturation factor 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0034382//chylomicron remnant clearance;GO:0090181//regulation of cholesterol metabolic process;GO:0009306//protein secretion;GO:0051604//protein maturation;GO:0090207//regulation of triglyceride metabolic process;GO:0033578//protein glycosylation in Golgi;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0051006//positive regulation of lipoprotein lipase activity,-,-
64789,0,0,58,2,22,5,0,0,10,69,12,0,EXO5;exonuclease 5,GO:0005829//cytosol;GO:0005634//nucleus,"GO:0000738//DNA catabolic process, exonucleolytic;GO:0036297//interstrand cross-link repair","GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0008310//single-stranded DNA 3'-5' exodeoxyribonuclease activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0051539//4 iron, 4 sulfur cluster binding",K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
64792,0,1,0,8,31,0,0,0,13,0,0,0,IFT22;intraflagellar transport 22,GO:0005929//cilium;GO:0030992//intraciliary transport particle B;GO:0005813//centrosome,GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
64793,0,0,0,1,0,14,47,0,40,0,0,0,CEP85;centrosomal protein 85kDa,GO:0005730//nucleolus;GO:0000922//spindle pole;GO:0005813//centrosome;GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12485//Endocytosis;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
64794,0,83,5,56,73,12,18,333,73,0,145,1,DDX31;DEAD (Asp-Glu-Ala-Asp) box polypeptide 31,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006200//ATP catabolic process,GO:0044822//poly(A) RNA binding;GO:0008026//ATP-dependent helicase activity;GO:0005524//ATP binding,-
64795,0,43,1,71,76,0,6,0,12,0,0,0,RMND5A;required for meiotic nuclear division 5 homolog A (S. cerevisiae),-,-,-,-
647979,0,244,8,415,1072,0,0,0,26,0,0,0,LINC00657;long intergenic non-protein coding RNA 657,-,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
64798,0,1,0,1,17,0,0,156,98,67,0,0,DEPTOR;DEP domain containing MTOR-interacting protein,GO:0005622//intracellular,GO:0035556//intracellular signal transduction;GO:0045792//negative regulation of cell size;GO:0006469//negative regulation of protein kinase activity;GO:0032007//negative regulation of TOR signaling;GO:2001236//regulation of extrinsic apoptotic signaling pathway,GO:0005515//protein binding,K12365//Chemokine signaling pathway
64799,0,98,0,32,55,10,0,138,59,72,7,0,IQCH;IQ motif containing H,-,-,-,-
648,0,0,0,0,0,0,0,0,0,0,4,0,"BMI1;BMI1 proto-oncogene, polycomb ring finger",GO:0035102//PRC1 complex;GO:0031519//PcG protein complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000151//ubiquitin ligase complex,"GO:0006351//transcription, DNA-templated;GO:0030097//hemopoiesis;GO:0007379//segment specification;GO:0010468//regulation of gene expression;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048146//positive regulation of fibroblast proliferation;GO:0016568//chromatin modification",GO:0005515//protein binding;GO:0071535//RING-like zinc finger domain binding;GO:0008270//zinc ion binding,K11459//Transcriptional misregulation in cancer
6480,85,0,2,8,40,26,25,27,14,79,13,0,"ST6GAL1;ST6 beta-galactosamide alpha-2,6-sialyltranferase 1",GO:0030173//integral component of Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane,GO:0097503//sialylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0006959//humoral immune response;GO:0006054//N-acetylneuraminate metabolic process,"GO:0003835//beta-galactoside alpha-2,6-sialyltransferase activity;GO:0008373//sialyltransferase activity",K00778//N-Glycan biosynthesis;Metabolic pathways;Other types of O-glycan biosynthesis
64800,0,32,0,0,0,15,0,0,31,174,18,0,EFCAB6;EF-hand calcium binding domain 6,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005509//calcium ion binding,-
64801,0,0,0,1,26,0,0,0,11,0,0,0,ARV1;ARV1 homolog (S. cerevisiae),GO:0016021//integral component of membrane,GO:0008206//bile acid metabolic process;GO:0030301//cholesterol transport;GO:0006665//sphingolipid metabolic process;GO:0090181//regulation of cholesterol metabolic process,-,-
64806,0,0,0,0,0,0,0,0,7,0,0,0,IL25;interleukin 25,GO:0005615//extracellular space,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030222//eosinophil differentiation;GO:0009620//response to fungus;GO:0009624//response to nematode;GO:0002437//inflammatory response to antigenic stimulus,GO:0005125//cytokine activity;GO:0030380//interleukin-17E receptor binding,K05493//Cytokine-cytokine receptor interaction
64816,0,0,0,0,0,1,0,0,11,0,1,0,"CYP3A43;cytochrome P450, family 3, subfamily A, polypeptide 43",GO:0005789//endoplasmic reticulum membrane,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process,GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0004497//monooxygenase activity;GO:0020037//heme binding,K07424//Drug metabolism - cytochrome P450;Metabolic pathways;Linoleic acid metabolism;Retinol metabolism;Bile secretion;Metabolism of xenobiotics by cytochrome P450;Drug metabolism - other enzymes;Steroid hormone biosynthesis
6482,43,0,0,0,0,0,0,0,39,0,0,70,"ST3GAL1;ST3 beta-galactoside alpha-2,3-sialyltransferase 1",GO:0016020//membrane;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0030173//integral component of Golgi membrane,GO:0097503//sialylation;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0006464//cellular protein modification process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0006487//protein N-linked glycosylation;GO:0044267//cellular protein metabolic process;GO:0006468//protein phosphorylation;GO:0006054//N-acetylneuraminate metabolic process,"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",K00780//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;Mucin type O-Glycan biosynthesis;Glycosphingolipid biosynthesis - ganglio series;Glycosaminoglycan biosynthesis - keratan sulfate
6483,57,0,1,8,0,0,20,0,5,198,7,0,"ST3GAL2;ST3 beta-galactoside alpha-2,3-sialyltransferase 2",GO:0000139//Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0030173//integral component of Golgi membrane;GO:0005576//extracellular region,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0006464//cellular protein modification process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0097503//sialylation;GO:0006040//amino sugar metabolic process;GO:0044267//cellular protein metabolic process,"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity",K03368//Glycosphingolipid biosynthesis - globo series;Mucin type O-Glycan biosynthesis;Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series;Glycosaminoglycan biosynthesis - keratan sulfate
64834,0,0,0,0,9,20,15,60,0,0,0,0,ELOVL1;ELOVL fatty acid elongase 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,"GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0019432//triglyceride biosynthetic process",GO:0005515//protein binding;GO:0009922//fatty acid elongase activity,K10247//Fatty acid elongation
64837,9,27,43,0,13,0,0,112,150,0,5,0,KLC2;kinesin light chain 2,GO:0005874//microtubule;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0035253//ciliary rootlet;GO:0043234//protein complex;GO:0016020//membrane;GO:0043005//neuron projection;GO:0016938//kinesin I complex,GO:0008152//metabolic process;GO:0008088//axon cargo transport;GO:0007018//microtubule-based movement;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation,GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0019894//kinesin binding,K10407//Salmonella infection
64838,0,0,0,5,79,0,0,1,3,0,0,0,FNDC4;fibronectin type III domain containing 4,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,-,-,-
64839,119,0,0,23,25,30,0,0,38,0,0,0,FBXL17;F-box and leucine-rich repeat protein 17,-,-,-,-
6484,0,0,1,0,10,0,9,33,5,0,4,0,"ST3GAL4;ST3 beta-galactoside alpha-2,3-sialyltransferase 4",GO:0070062//extracellular vesicular exosome;GO:0030173//integral component of Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0097503//sialylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0050890//cognition;GO:0044267//cellular protein metabolic process,"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0047288//monosialoganglioside sialyltransferase activity",K03494//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
64840,0,0,0,0,0,20,0,0,12,0,6,0,PORCN;porcupine homolog (Drosophila),GO:0030176//integral component of endoplasmic reticulum membrane;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0009100//glycoprotein metabolic process;GO:0016055//Wnt signaling pathway,"GO:0016746//transferase activity, transferring acyl groups",K00181//Wnt signaling pathway
64841,0,2,0,65,209,16,0,0,25,0,0,0,GNPNAT1;glucosamine-phosphate N-acetyltransferase 1,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0000139//Golgi membrane;GO:0005770//late endosome;GO:0005829//cytosol;GO:0010008//endosome membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006041//glucosamine metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0001889//liver development;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0006044//N-acetylglucosamine metabolic process,GO:0004343//glucosamine 6-phosphate N-acetyltransferase activity;GO:0048029//monosaccharide binding,K00621//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
64843,0,0,0,7,0,0,0,55,33,0,0,0,ISL2;ISL LIM homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0021524//visceral motor neuron differentiation;GO:0048666//neuron development;GO:0031290//retinal ganglion cell axon guidance;GO:0045665//negative regulation of neuron differentiation;GO:0048935//peripheral nervous system neuron development;GO:0021520//spinal cord motor neuron cell fate specification",GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
64844,0,32,0,49,79,0,0,0,29,0,0,0,"MARCH7;membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase",-,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
64847,191,2,0,7,5,27,0,0,0,1,0,1,SPATA20;spermatogenesis associated 20,GO:0005576//extracellular region,GO:0007275//multicellular organismal development;GO:0008152//metabolic process;GO:0007283//spermatogenesis;GO:0030154//cell differentiation,GO:0003824//catalytic activity,-
64848,0,54,0,30,55,18,50,0,85,0,0,0,YTHDC2;YTH domain containing 2,GO:0005783//endoplasmic reticulum,GO:0044829//positive regulation by host of viral genome replication;GO:0070555//response to interleukin-1;GO:0034612//response to tumor necrosis factor;GO:0006200//ATP catabolic process,GO:0004386//helicase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008186//RNA-dependent ATPase activity;GO:0005524//ATP binding;GO:0070063//RNA polymerase binding,K14442//RNA degradation
64849,166,0,0,0,0,0,54,0,43,0,30,0,"SLC13A3;solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0006835//dicarboxylic acid transport;GO:0006814//sodium ion transport,GO:0015362//high-affinity sodium:dicarboxylate symporter activity,-
64850,0,0,0,0,0,0,11,0,36,0,0,0,ETNPPL;ethanolamine-phosphate phospho-lyase,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0030170//pyridoxal phosphate binding;GO:0008483//transaminase activity;GO:0050459//ethanolamine-phosphate phospho-lyase activity,-
64852,0,0,0,35,22,0,2,0,40,0,24,0,"TUT1;terminal uridylyl transferase 1, U6 snRNA-specific",GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex,GO:0071044//histone mRNA catabolic process;GO:0006378//mRNA polyadenylation;GO:0006379//mRNA cleavage;GO:0016180//snRNA processing,GO:0050265//RNA uridylyltransferase activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0003730//mRNA 3'-UTR binding,-
64853,1,0,0,16,52,38,3,0,0,0,0,0,"AIDA;axin interactor, dorsalization associated",GO:0005737//cytoplasm,GO:0009953//dorsal/ventral pattern formation;GO:0043508//negative regulation of JUN kinase activity;GO:0043496//regulation of protein homodimerization activity;GO:0046329//negative regulation of JNK cascade,GO:0019904//protein domain specific binding,-
64854,0,0,0,26,69,0,36,90,68,0,0,0,USP46;ubiquitin specific peptidase 46,-,"GO:0001662//behavioral fear response;GO:0016579//protein deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0048149//behavioral response to ethanol;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0008343//adult feeding behavior;GO:0060013//righting reflex",GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,-
64855,0,38,0,6,15,0,22,0,26,0,12,0,"FAM129B;family with sequence similarity 129, member B",GO:0005634//nucleus;GO:0005912//adherens junction;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0043066//negative regulation of apoptotic process,-,-
64856,0,0,0,0,0,0,17,7,9,54,0,0,VWA1;von Willebrand factor A domain containing 1,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0005614//interstitial matrix,GO:0048266//behavioral response to pain;GO:0030198//extracellular matrix organization,GO:0042802//identical protein binding,K08132//Protein digestion and absorption
64857,8,0,0,6,0,6,0,0,62,152,7,0,"PLEKHG2;pleckstrin homology domain containing, family G (with RhoGef domain) member 2",GO:0005829//cytosol,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K05769//Regulation of actin cytoskeleton
64858,0,0,0,0,9,0,0,0,15,0,0,0,DCLRE1B;DNA cross-link repair 1B,"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm",GO:0031860//telomeric 3' overhang formation;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0031627//telomeric loop formation;GO:0031848//protection from non-homologous end joining at telomere;GO:0000075//cell cycle checkpoint;GO:0000723//telomere maintenance,GO:0008409//5'-3' exonuclease activity;GO:0005515//protein binding,-
64859,155,0,0,0,0,10,0,44,0,0,0,1,NABP1;nucleic acid binding protein 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070876//SOSS complex;GO:0005730//nucleolus,GO:0006974//cellular response to DNA damage stimulus;GO:0007093//mitotic cell cycle checkpoint;GO:0000724//double-strand break repair via homologous recombination;GO:0010212//response to ionizing radiation;GO:0006281//DNA repair,GO:0003697//single-stranded DNA binding;GO:0003723//RNA binding,-
64860,60,14,0,2,91,14,0,0,0,0,0,0,"ARMCX5;armadillo repeat containing, X-linked 5",-,-,-,K14284//Influenza A;Ribosome biogenesis in eukaryotes;RNA transport;mRNA surveillance pathway;Herpes simplex infection
64863,0,35,0,0,31,31,0,70,115,0,0,0,METTL4;methyltransferase like 4,-,GO:0032259//methylation;GO:0006139//nucleobase-containing compound metabolic process,GO:0003676//nucleic acid binding;GO:0008168//methyltransferase activity,-
64864,0,0,0,13,33,0,0,54,34,116,2,0,"RFX7;regulatory factor X, 7",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,K08061//Primary immunodeficiency;Antigen processing and presentation;Tuberculosis
64866,1,0,0,3,0,0,83,12,35,0,0,0,CDCP1;CUB domain containing protein 1,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,-
6487,59,0,0,0,2,20,0,0,34,0,0,0,"ST3GAL3;ST3 beta-galactoside alpha-2,3-sialyltransferase 3",GO:0030173//integral component of Golgi membrane;GO:0005576//extracellular region;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0097503//sialylation;GO:0044267//cellular protein metabolic process,"GO:0003836//beta-galactoside (CMP) alpha-2,3-sialyltransferase activity;GO:0008118//N-acetyllactosaminide alpha-2,3-sialyltransferase activity",K00781//Glycosphingolipid biosynthesis - lacto and neolacto series;Glycosaminoglycan biosynthesis - keratan sulfate;Other types of O-glycan biosynthesis;Metabolic pathways
648740,0,0,0,0,0,0,0,0,6,0,0,0,"ACTG1P4;actin, gamma 1 pseudogene 4",-,-,-,K05692//Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Adherens junction;Phototransduction - fly;Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion
648791,4,0,0,0,0,0,16,0,0,0,0,0,"PPP1R3G;protein phosphatase 1, regulatory subunit 3G",GO:0005737//cytoplasm,GO:0045725//positive regulation of glycogen biosynthetic process;GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:0042593//glucose homeostasis,GO:2001069//glycogen binding;GO:0019903//protein phosphatase binding,K07189//Insulin signaling pathway
64881,0,0,0,0,0,35,0,0,9,0,1,0,PCDH20;protocadherin 20,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0044822//poly(A) RNA binding;GO:0005509//calcium ion binding,-
6489,70,0,0,0,10,60,0,61,118,0,17,1,"ST8SIA1;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1",GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane,GO:0006688//glycosphingolipid biosynthetic process;GO:0097503//sialylation;GO:0034605//cellular response to heat;GO:0008284//positive regulation of cell proliferation;GO:0005975//carbohydrate metabolic process;GO:0006486//protein glycosylation,"GO:0008373//sialyltransferase activity;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",K03371//Glycosphingolipid biosynthesis - ganglio series;Metabolic pathways;Glycosphingolipid biosynthesis - globo series;Glycosphingolipid biosynthesis - lacto and neolacto series
64895,0,1,0,0,27,32,25,4,62,0,8,0,PAPOLG;poly(A) polymerase gamma,GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043631//RNA polyadenylation;GO:0006378//mRNA polyadenylation,GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0004652//polynucleotide adenylyltransferase activity;GO:0046872//metal ion binding,K14376//mRNA surveillance pathway
64897,0,29,0,0,1,17,100,0,9,0,0,0,C12orf43;chromosome 12 open reading frame 43,-,-,-,K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
649,0,0,0,0,0,31,48,14,15,0,12,20,BMP1;bone morphogenetic protein 1,GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0005615//extracellular space;GO:0031988//membrane-bounded vesicle;GO:0005578//proteinaceous extracellular matrix,GO:0001501//skeletal system development;GO:0006508//proteolysis;GO:0007275//multicellular organismal development;GO:0001502//cartilage condensation;GO:0042157//lipoprotein metabolic process;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0001503//ossification;GO:0030154//cell differentiation;GO:0044281//small molecule metabolic process;GO:0061036//positive regulation of cartilage development,GO:0005125//cytokine activity;GO:0008270//zinc ion binding;GO:0008083//growth factor activity;GO:0008237//metallopeptidase activity;GO:0005509//calcium ion binding;GO:0008233//peptidase activity;GO:0004222//metalloendopeptidase activity,-
6490,0,0,0,0,0,0,0,0,0,155,0,0,PMEL;premelanosome protein,GO:0005789//endoplasmic reticulum membrane;GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0032585//multivesicular body membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0032438//melanosome organization;GO:0042438//melanin biosynthetic process,GO:0005515//protein binding,K10955//Amoebiasis;Vibrio cholerae infection
64901,200,1,0,8,0,25,0,0,31,0,0,0,RANBP17;RAN binding protein 17,GO:0005643//nuclear pore;GO:0005737//cytoplasm,GO:0006606//protein import into nucleus;GO:0051028//mRNA transport,GO:0005525//GTP binding;GO:0008536//Ran GTPase binding,K05189//GABAergic synapse;Nicotine addiction;Morphine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
64902,3,0,0,0,0,11,37,0,0,0,0,0,AGXT2;alanine--glyoxylate aminotransferase 2,GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,"GO:0019481//L-alanine catabolic process, by transamination;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046487//glyoxylate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0046135//pyrimidine nucleoside catabolic process;GO:0009436//glyoxylate catabolic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0019265//glycine biosynthetic process, by transamination of glyoxylate",GO:0008453//alanine-glyoxylate transaminase activity;GO:0016223//beta-alanine-pyruvate transaminase activity;GO:0047305//(R)-3-amino-2-methylpropionate-pyruvate transaminase activity;GO:0030170//pyridoxal phosphate binding,"K00827//Alanine, aspartate and glutamate metabolism;Metabolic pathways;Glycine, serine and threonine metabolism"
6491,0,0,0,0,0,35,0,0,18,0,5,0,STIL;SCL/TAL1 interrupting locus,GO:0005829//cytosol;GO:0005813//centrosome,GO:0030900//forebrain development;GO:0043066//negative regulation of apoptotic process;GO:0035264//multicellular organism growth;GO:0008283//cell proliferation;GO:0001947//heart looping;GO:0001843//neural tube closure;GO:0007368//determination of left/right symmetry;GO:0030903//notochord development;GO:0033504//floor plate development;GO:0001701//in utero embryonic development;GO:0007224//smoothened signaling pathway;GO:0000578//embryonic axis specification;GO:0021915//neural tube development,GO:0005515//protein binding,K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
649159,0,0,0,0,0,0,0,0,38,0,0,0,LINC00273;long intergenic non-protein coding RNA 273,-,-,-,K13911//Salivary secretion
64919,118,0,0,0,0,8,30,0,3,0,7,0,BCL11B;B-cell CLL/lymphoma 11B (zinc finger protein),GO:0005634//nucleus,"GO:0071678//olfactory bulb axon guidance;GO:0031077//post-embryonic camera-type eye development;GO:0043368//positive T cell selection;GO:0021773//striatal medium spiny neuron differentiation;GO:0033077//T cell differentiation in thymus;GO:0003334//keratinocyte development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042475//odontogenesis of dentin-containing tooth;GO:0003382//epithelial cell morphogenesis;GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0019216//regulation of lipid metabolic process;GO:0046632//alpha-beta T cell differentiation;GO:0048538//thymus development;GO:0045664//regulation of neuron differentiation;GO:0033153//T cell receptor V(D)J recombination;GO:0010837//regulation of keratinocyte proliferation",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
6492,0,0,0,0,0,39,0,0,49,0,0,0,SIM1;single-minded family bHLH transcription factor 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation;GO:0007399//nervous system development;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0001657//ureteric bud development",GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity,-
64921,0,1,29,18,16,16,0,0,51,0,8,0,CASD1;CAS1 domain containing 1,GO:0016021//integral component of membrane,-,-,K06236//Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
64922,0,0,23,0,0,0,0,0,32,0,1,112,LRRC19;leucine rich repeat containing 19,GO:0016021//integral component of membrane,-,-,-
64924,0,0,1,31,13,0,7,4,0,0,24,0,"SLC30A5;solute carrier family 30 (zinc transporter), member 5",GO:0016324//apical plasma membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005887//integral component of plasma membrane;GO:0005634//nucleus;GO:0030667//secretory granule membrane;GO:0030141//secretory granule;GO:0005730//nucleolus,GO:0006824//cobalt ion transport;GO:0071577//zinc ion transmembrane transport;GO:0055085//transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0006829//zinc ion transport;GO:0010155//regulation of proton transport;GO:0010043//response to zinc ion;GO:0006882//cellular zinc ion homeostasis,GO:0005385//zinc ion transmembrane transporter activity;GO:0008270//zinc ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
64925,0,0,0,0,1,0,0,0,8,0,9,0,CCDC71;coiled-coil domain containing 71,-,-,-,-
649264,0,0,0,0,0,0,0,0,14,0,0,0,CES5AP1;carboxylesterase 5A pseudogene 1,-,-,-,-
64927,94,27,0,0,16,0,41,0,10,32,9,0,TTC23;tetratricopeptide repeat domain 23,-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K14209//Protein digestion and absorption;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism
64928,0,55,0,1,10,0,0,76,0,0,0,0,MRPL14;mitochondrial ribosomal protein L14,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
6493,0,42,0,89,44,0,0,69,36,127,94,0,SIM2;single-minded family bHLH transcription factor 2,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0030324//lung development;GO:0006351//transcription, DNA-templated;GO:0009880//embryonic pattern specification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0007399//nervous system development",GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity,-
6494,52,0,0,12,13,2,0,0,29,3,11,9,SIPA1;signal-induced proliferation-associated 1,GO:0005829//cytosol;GO:0016020//membrane;GO:0043234//protein complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030133//transport vesicle,GO:0008283//cell proliferation;GO:0007162//negative regulation of cell adhesion;GO:0032854//positive regulation of Rap GTPase activity;GO:0035556//intracellular signal transduction;GO:0030308//negative regulation of cell growth;GO:0007010//cytoskeleton organization;GO:0042631//cellular response to water deprivation;GO:0045786//negative regulation of cell cycle;GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005515//protein binding;GO:0046582//Rap GTPase activator activity;GO:0005096//GTPase activator activity;GO:0008022//protein C-terminus binding,K08013//Leukocyte transendothelial migration
64940,0,0,0,0,9,0,0,0,0,0,0,0,STAG3L4;stromal antigen 3-like 4 (pseudogene),-,-,-,K13055//Oocyte meiosis
64943,0,0,0,0,0,21,0,1,24,159,0,0,NT5DC2;5'-nucleotidase domain containing 2,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K01081//Nicotinate and nicotinamide metabolism;Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
64946,0,0,0,0,0,10,0,0,0,0,0,0,CENPH;centromere protein H,GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0051382//kinetochore assembly;GO:0000278//mitotic cell cycle;GO:0051383//kinetochore organization;GO:0034080//CENP-A containing nucleosome assembly;GO:0006334//nucleosome assembly,GO:0005515//protein binding;GO:0043515//kinetochore binding,-
64949,0,15,0,2,0,0,0,0,15,0,0,0,MRPS26;mitochondrial ribosomal protein S26,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005763//mitochondrial small ribosomal subunit,"GO:0042769//DNA damage response, detection of DNA damage;GO:0043043//peptide biosynthetic process",GO:0044822//poly(A) RNA binding,-
6495,0,68,0,0,35,0,0,0,16,71,1,556,SIX1;SIX homeobox 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0001658//branching involved in ureteric bud morphogenesis;GO:0001657//ureteric bud development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030878//thyroid gland development;GO:0008582//regulation of synaptic growth at neuromuscular junction;GO:0034504//protein localization to nucleus;GO:0006915//apoptotic process;GO:0051451//myoblast migration;GO:0048699//generation of neurons;GO:0072193//ureter smooth muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072075//metanephric mesenchyme development;GO:0048538//thymus development;GO:0060037//pharyngeal system development;GO:0007605//sensory perception of sound;GO:0007389//pattern specification process;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000729//positive regulation of mesenchymal cell proliferation involved in ureter development;GO:0090103//cochlea morphogenesis;GO:0048839//inner ear development;GO:0003151//outflow tract morphogenesis;GO:0042474//middle ear morphogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0035909//aorta morphogenesis;GO:0048704//embryonic skeletal system morphogenesis;GO:0030855//epithelial cell differentiation;GO:0071599//otic vesicle development;GO:0072107//positive regulation of ureteric bud formation;GO:0021610//facial nerve morphogenesis;GO:0007519//skeletal muscle tissue development;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis;GO:0001759//organ induction;GO:0001822//kidney development;GO:0045664//regulation of neuron differentiation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0042472//inner ear morphogenesis;GO:0048665//neuron fate specification;GO:0032880//regulation of protein localization;GO:0072172//mesonephric tubule formation;GO:0006351//transcription, DNA-templated;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0072095//regulation of branch elongation involved in ureteric bud branching",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding;GO:0044212//transcription regulatory region DNA binding,K15614//Transcriptional misregulation in cancer
6496,0,0,0,0,0,0,3,1,48,0,0,0,SIX3;SIX homeobox 3,GO:0005634//nucleus,"GO:0021536//diencephalon development;GO:0007420//brain development;GO:0021797//forebrain anterior/posterior pattern specification;GO:0048512//circadian behavior;GO:0001654//eye development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0060235//lens induction in camera-type eye;GO:0021537//telencephalon development;GO:0007601//visual perception;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006606//protein import into nucleus",GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001222//transcription corepressor binding;GO:0005515//protein binding,K15614//Transcriptional misregulation in cancer
64960,0,0,0,1,86,7,0,0,0,0,0,0,MRPS15;mitochondrial ribosomal protein S15,GO:0005763//mitochondrial small ribosomal subunit;GO:0031965//nuclear membrane;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
64963,23,0,0,0,2,0,17,0,5,0,0,0,MRPS11;mitochondrial ribosomal protein S11,GO:0005763//mitochondrial small ribosomal subunit;GO:0005739//mitochondrion,"GO:0042769//DNA damage response, detection of DNA damage;GO:0006412//translation",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
64965,0,0,1,13,0,0,0,0,32,0,18,0,MRPS9;mitochondrial ribosomal protein S9,GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005763//mitochondrial small ribosomal subunit,"GO:0006412//translation;GO:0043043//peptide biosynthetic process;GO:0042769//DNA damage response, detection of DNA damage",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,K02960//Ribosome
64968,0,0,0,0,37,0,0,0,13,0,0,0,MRPS6;mitochondrial ribosomal protein S6,GO:0015935//small ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0019843//rRNA binding,-
64969,97,27,0,6,91,30,0,0,5,0,7,1,MRPS5;mitochondrial ribosomal protein S5,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
6497,0,0,0,0,98,0,0,0,19,0,0,0,SKI;SKI proto-oncogene,GO:0017053//transcriptional repressor complex;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016604//nuclear body;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0032926//negative regulation of activin receptor signaling pathway;GO:0048147//negative regulation of fibroblast proliferation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0070207//protein homotrimerization;GO:0021772//olfactory bulb development;GO:0045668//negative regulation of osteoblast differentiation;GO:0014902//myotube differentiation;GO:0030514//negative regulation of BMP signaling pathway;GO:0042981//regulation of apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043585//nose morphogenesis;GO:0060325//face morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0022011//myelination in peripheral nervous system;GO:0048593//camera-type eye morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060395//SMAD protein signal transduction;GO:0048870//cell motility;GO:0060349//bone morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0001843//neural tube closure;GO:0035019//somatic stem cell maintenance;GO:0060041//retina development in camera-type eye;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0010626//negative regulation of Schwann cell proliferation;GO:0060021//palate development;GO:0030509//BMP signaling pathway;GO:0031064//negative regulation of histone deacetylation;GO:0008283//cell proliferation;GO:0043388//positive regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0048741//skeletal muscle fiber development;GO:0043010//camera-type eye development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002089//lens morphogenesis in camera-type eye;GO:0030326//embryonic limb morphogenesis",GO:0019904//protein domain specific binding;GO:0046332//SMAD binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0046811//histone deacetylase inhibitor activity;GO:0070491//repressing transcription factor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
64975,0,1,0,6,1,0,0,3,12,0,0,0,MRPL41;mitochondrial ribosomal protein L41,GO:0030529//ribonucleoprotein complex;GO:0005739//mitochondrion;GO:0005762//mitochondrial large ribosomal subunit,GO:0007049//cell cycle;GO:0006915//apoptotic process;GO:0006412//translation,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
64976,0,0,0,15,5,0,17,0,18,0,0,0,MRPL40;mitochondrial ribosomal protein L40,GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005761//mitochondrial ribosome;GO:0005634//nucleus,GO:0009653//anatomical structure morphogenesis,GO:0044822//poly(A) RNA binding,-
64978,0,0,0,1,1,0,0,0,8,77,0,0,MRPL38;mitochondrial ribosomal protein L38,GO:0005739//mitochondrion;GO:0005840//ribosome,-,-,-
64979,0,0,0,0,2,0,9,0,0,0,0,0,MRPL36;mitochondrial ribosomal protein L36,GO:0005762//mitochondrial large ribosomal subunit,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
6498,0,15,1,5,68,0,17,0,37,64,0,0,SKIL;SKI-like proto-oncogene,GO:0001669//acrosomal vesicle;GO:0016605//PML body;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001825//blastocyst formation;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0070208//protein heterotrimerization;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0046677//response to antibiotic;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0010467//gene expression;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0002260//lymphocyte homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070306//lens fiber cell differentiation;GO:0042981//regulation of apoptotic process;GO:0050772//positive regulation of axonogenesis;GO:0007050//cell cycle arrest;GO:0034097//response to cytokine;GO:0045596//negative regulation of cell differentiation;GO:0070207//protein homotrimerization;GO:0007519//skeletal muscle tissue development;GO:0070848//response to growth factor;GO:0007283//spermatogenesis",GO:0003682//chromatin binding;GO:0032403//protein complex binding;GO:0003714//transcription corepressor activity;GO:0019904//protein domain specific binding;GO:0046332//SMAD binding;GO:0003677//DNA binding;GO:0005515//protein binding,K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
64981,0,0,0,0,0,35,0,0,29,0,0,0,MRPL34;mitochondrial ribosomal protein L34,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
64983,0,36,0,0,2,0,45,0,0,0,0,0,MRPL32;mitochondrial ribosomal protein L32,GO:0015934//large ribosomal subunit;GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,-
6499,14,0,0,0,12,0,0,0,0,0,0,0,SKIV2L;superkiller viralicidic activity 2-like (S. cerevisiae),GO:0055087//Ski complex;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0006200//ATP catabolic process,GO:0004004//ATP-dependent RNA helicase activity;GO:0005524//ATP binding;GO:0003723//RNA binding,K12599//RNA degradation
650,0,0,0,0,0,0,0,38,15,0,10,0,BMP2;bone morphogenetic protein 2,GO:0005576//extracellular region;GO:0009986//cell surface;GO:0005615//extracellular space,"GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001666//response to hypoxia;GO:0010922//positive regulation of phosphatase activity;GO:0060485//mesenchyme development;GO:0055114//oxidation-reduction process;GO:0048711//positive regulation of astrocyte differentiation;GO:0006468//protein phosphorylation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0035051//cardiocyte differentiation;GO:0045778//positive regulation of ossification;GO:0043065//positive regulation of apoptotic process;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000187//activation of MAPK activity;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0030335//positive regulation of cell migration;GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment;GO:0030198//extracellular matrix organization;GO:0007267//cell-cell signaling;GO:0045669//positive regulation of osteoblast differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0048762//mesenchymal cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0001501//skeletal system development;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0055008//cardiac muscle tissue morphogenesis;GO:0030282//bone mineralization;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0040007//growth;GO:0001934//positive regulation of protein phosphorylation;GO:1900745//positive regulation of p38MAPK cascade;GO:0060039//pericardium development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001649//osteoblast differentiation;GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0045666//positive regulation of neuron differentiation;GO:0030501//positive regulation of bone mineralization;GO:0045600//positive regulation of fat cell differentiation;GO:0060128//corticotropin hormone secreting cell differentiation;GO:0071407//cellular response to organic cyclic compound;GO:0051042//negative regulation of calcium-independent cell-cell adhesion;GO:0009887//organ morphogenesis;GO:0043410//positive regulation of MAPK cascade;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:0060129//thyroid-stimulating hormone-secreting cell differentiation;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007507//heart development;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042482//positive regulation of odontogenesis;GO:0055007//cardiac muscle cell differentiation;GO:0031648//protein destabilization;GO:0035630//bone mineralization involved in bone maturation;GO:0060804//positive regulation of Wnt signaling pathway by BMP signaling pathway;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0061036//positive regulation of cartilage development;GO:0007219//Notch signaling pathway;GO:0010894//negative regulation of steroid biosynthetic process;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002062//chondrocyte differentiation;GO:0060395//SMAD protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000065//negative regulation of cortisol biosynthetic process;GO:0001701//in utero embryonic development;GO:0006029//proteoglycan metabolic process;GO:0071773//cellular response to BMP stimulus;GO:0003130//BMP signaling pathway involved in heart induction;GO:0045786//negative regulation of cell cycle;GO:0003181//atrioventricular valve morphogenesis;GO:0048839//inner ear development;GO:0021537//telencephalon development;GO:0021978//telencephalon regionalization;GO:0033690//positive regulation of osteoblast proliferation;GO:0003308//negative regulation of Wnt signaling pathway involved in heart development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0030509//BMP signaling pathway;GO:2000726//negative regulation of cardiac muscle cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0009790//embryo development",GO:0046332//SMAD binding;GO:0004745//retinol dehydrogenase activity;GO:0070700//BMP receptor binding;GO:0005102//receptor binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0019211//phosphatase activator activity,K04662//Cytokine-cytokine receptor interaction;Hedgehog signaling pathway;Pathways in cancer;TGF-beta signaling pathway;Basal cell carcinoma
6500,0,20,1,247,433,0,0,0,41,0,0,0,SKP1;S-phase kinase-associated protein 1,GO:0070062//extracellular vesicular exosome;GO:0031519//PcG protein complex;GO:0005829//cytosol;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0019005//SCF ubiquitin ligase complex,GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0016567//protein ubiquitination;GO:0007219//Notch signaling pathway;GO:0035518//histone H2A monoubiquitination;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K03094//Circadian rhythm - mammal;Ubiquitin mediated proteolysis;TGF-beta signaling pathway;Cell cycle - yeast;Cell cycle;Protein processing in endoplasmic reticulum;Herpes simplex infection;Wnt signaling pathway;Oocyte meiosis
65003,0,0,0,0,19,14,0,0,0,0,0,0,MRPL11;mitochondrial ribosomal protein L11,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,-
65008,87,0,0,3,15,0,0,0,14,0,0,0,MRPL1;mitochondrial ribosomal protein L1,GO:0005739//mitochondrion;GO:0015934//large ribosomal subunit;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding,-
65009,0,21,0,0,0,31,29,0,33,0,66,0,NDRG4;NDRG family member 4,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006950//response to stress;GO:0030154//cell differentiation;GO:0016049//cell growth,-,-
65010,148,0,0,0,0,12,0,0,41,0,1,0,"SLC26A6;solute carrier family 26 (anion exchanger), member 6",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0016324//apical plasma membrane;GO:0097225//sperm midpiece;GO:0034707//chloride channel complex;GO:0031988//membrane-bounded vesicle;GO:0016323//basolateral plasma membrane;GO:0012506//vesicle membrane,GO:0046724//oxalic acid secretion;GO:0071346//cellular response to interferon-gamma;GO:0008272//sulfate transport;GO:2001150//positive regulation of dipeptide transmembrane transport;GO:0030321//transepithelial chloride transport;GO:0015724//formate transport;GO:1902476//chloride transmembrane transport;GO:0070633//transepithelial transport;GO:0015701//bicarbonate transport;GO:0038166//angiotensin-activated signaling pathway;GO:0071320//cellular response to cAMP;GO:0071332//cellular response to fructose stimulus;GO:0006820//anion transport;GO:0019532//oxalate transport;GO:0006821//chloride transport;GO:0015797//mannitol transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0050892//intestinal absorption;GO:0051454//intracellular pH elevation;GO:0042045//epithelial fluid transport;GO:1902358//sulfate transmembrane transport;GO:0070528//protein kinase C signaling;GO:0048240//sperm capacitation;GO:0006811//ion transport,GO:0030165//PDZ domain binding;GO:0008271//secondary active sulfate transmembrane transporter activity;GO:0015660//formate efflux transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0005515//protein binding;GO:0015106//bicarbonate transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0015301//anion:anion antiporter activity;GO:0019531//oxalate transmembrane transporter activity;GO:0015659//formate uptake transmembrane transporter activity;GO:0015116//sulfate transmembrane transporter activity;GO:0015562//efflux transmembrane transporter activity,K14704//Mineral absorption
65012,6,0,1,0,26,58,6,42,9,0,0,0,"SLC26A10;solute carrier family 26, member 10",GO:0016021//integral component of membrane,GO:1902358//sulfate transmembrane transport,GO:0015116//sulfate transmembrane transporter activity;GO:0015297//antiporter activity,-
65018,1,33,23,13,52,36,0,47,0,0,0,0,PINK1;PTEN induced putative kinase 1,GO:0005741//mitochondrial outer membrane;GO:0005758//mitochondrial intermembrane space;GO:0097449//astrocyte projection;GO:0031932//TORC2 complex;GO:0048471//perinuclear region of cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005856//cytoskeleton;GO:0031307//integral component of mitochondrial outer membrane;GO:0005737//cytoplasm;GO:0044297//cell body;GO:0016020//membrane;GO:0005634//nucleus;GO:0000785//chromatin;GO:0030424//axon,"GO:2000377//regulation of reactive oxygen species metabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0033603//positive regulation of dopamine secretion;GO:0010629//negative regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:0008219//cell death;GO:0031396//regulation of protein ubiquitination;GO:0032226//positive regulation of synaptic transmission, dopaminergic;GO:0071456//cellular response to hypoxia;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0016567//protein ubiquitination;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0097237//cellular response to toxic substance;GO:0035556//intracellular signal transduction;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0016310//phosphorylation;GO:0043524//negative regulation of neuron apoptotic process;GO:0032148//activation of protein kinase B activity;GO:0007005//mitochondrion organization;GO:0018105//peptidyl-serine phosphorylation;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0043254//regulation of protein complex assembly;GO:0051881//regulation of mitochondrial membrane potential;GO:0006468//protein phosphorylation;GO:0038203//TORC2 signaling;GO:0000422//mitochondrion degradation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006979//response to oxidative stress;GO:0010952//positive regulation of peptidase activity;GO:0006950//response to stress",GO:0031625//ubiquitin protein ligase binding;GO:0010857//calcium-dependent protein kinase activity;GO:0016504//peptidase activator activity;GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0055131//C3HC4-type RING finger domain binding;GO:0004674//protein serine/threonine kinase activity;GO:0043422//protein kinase B binding;GO:0005515//protein binding;GO:0002020//protease binding;GO:0000287//magnesium ion binding,K05688//Parkinson's disease
6502,0,0,0,0,0,0,0,51,30,112,0,0,"SKP2;S-phase kinase-associated protein 2, E3 ubiquitin protein ligase",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0019005//SCF ubiquitin ligase complex;GO:0005634//nucleus;GO:0016235//aggresome;GO:0005737//cytoplasm,GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0071460//cellular response to cell-matrix adhesion;GO:0000209//protein polyubiquitination;GO:0008283//cell proliferation;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0042802//identical protein binding,K03875//Herpes simplex infection;Pathways in cancer;Cell cycle;Ubiquitin mediated proteolysis;Small cell lung cancer;Epstein-Barr virus infection
650226,0,0,0,0,0,0,6,0,9,0,0,0,LOC650226;ankyrin repeat domain 26 pseudogene,-,-,-,-
650293,0,0,0,0,0,0,22,0,16,0,0,0,LOC650293;seven transmembrane helix receptor,-,-,-,K04257//Olfactory transduction
6503,0,0,0,0,0,43,0,0,18,0,0,0,SLA;Src-like-adaptor,GO:0005768//endosome,GO:0009967//positive regulation of signal transduction,GO:0005515//protein binding;GO:0005070//SH3/SH2 adaptor activity,K05854//Chemokine signaling pathway;Fc epsilon RI signaling pathway;Long-term depression;NF-kappa B signaling pathway;Fc gamma R-mediated phagocytosis;B cell receptor signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;K08893//Chemokine signaling pathway;Fc gamma R-mediated phagocytosis
650368,0,0,0,0,0,0,1,0,34,61,0,0,LOC650368;asparagine-linked glycosylation 1-like pseudogene,-,-,-,K03842//N-Glycan biosynthesis;Metabolic pathways;Various types of N-glycan biosynthesis
6504,0,0,0,0,0,0,0,82,22,19,28,0,SLAMF1;signaling lymphocytic activation molecule family member 1,GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0045335//phagocytic vesicle;GO:0016021//integral component of membrane,GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:0031338//regulation of vesicle fusion;GO:0046649//lymphocyte activation;GO:0008284//positive regulation of cell proliferation;GO:0016032//viral process,GO:0003823//antigen binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K06536//Measles
6505,0,0,0,0,12,0,0,110,30,0,27,0,"SLC1A1;solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0070779//D-aspartate import;GO:0051260//protein homooligomerization;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0051938//L-glutamate import;GO:0007268//synaptic transmission,GO:0015501//glutamate:sodium symporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0016595//glutamate binding,K05612//Glutamatergic synapse;Protein digestion and absorption
65055,0,0,0,0,0,0,0,0,6,0,8,0,REEP1;receptor accessory protein 1,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0008219//cell death;GO:0071786//endoplasmic reticulum tubular network organization;GO:0051205//protein insertion into membrane;GO:0032386//regulation of intracellular transport,GO:0031849//olfactory receptor binding;GO:0008017//microtubule binding;GO:0005515//protein binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
65056,87,30,0,43,210,0,0,114,47,0,0,0,GPBP1;GC-rich promoter binding protein 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
65057,0,0,0,0,0,0,0,0,14,0,0,293,ACD;adrenocortical dysplasia homolog (mouse),"GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex","GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0070198//protein localization to chromosome, telomeric region;GO:0006886//intracellular protein transport;GO:0032202//telomere assembly;GO:0016233//telomere capping;GO:0000723//telomere maintenance;GO:0051973//positive regulation of telomerase activity;GO:0060381//positive regulation of single-stranded telomeric DNA binding;GO:0031848//protection from non-homologous end joining at telomere",GO:0005515//protein binding;GO:0070182//DNA polymerase binding;GO:0003677//DNA binding,-
65059,62,35,1,49,132,59,32,24,37,0,8,1,RAPH1;Ras association (RalGDS/AF-6) and pleckstrin homology domains 1,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0030175//filopodium,GO:0007160//cell-matrix adhesion;GO:0048675//axon extension;GO:0007165//signal transduction,-,K03956//Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
6506,0,0,0,0,0,112,14,43,118,0,4,0,"SLC1A2;solute carrier family 1 (glial high affinity glutamate transporter), member 2",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0030673//axolemma,GO:0042493//response to drug;GO:0010259//multicellular organismal aging;GO:0007632//visual behavior;GO:0009611//response to wounding;GO:0021537//telencephalon development;GO:0070779//D-aspartate import;GO:0043200//response to amino acid;GO:0035264//multicellular organism growth;GO:0046326//positive regulation of glucose import;GO:0030534//adult behavior;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0051938//L-glutamate import;GO:0031668//cellular response to extracellular stimulus;GO:0007268//synaptic transmission,GO:0005313//L-glutamate transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0005515//protein binding;GO:0015501//glutamate:sodium symporter activity,K05613//Glutamatergic synapse;Amyotrophic lateral sclerosis (ALS)
65061,9,0,0,0,0,31,6,60,40,9,0,0,CDK15;cyclin-dependent kinase 15,-,GO:0051726//regulation of cell cycle;GO:0006468//protein phosphorylation,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
65062,0,0,0,0,0,23,0,0,72,0,0,0,TMEM237;transmembrane protein 237,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0035869//ciliary transition zone,GO:0030111//regulation of Wnt signaling pathway;GO:0042384//cilium assembly,-,K01689//Metabolic pathways;RNA degradation;Microbial metabolism in diverse environments;Methane metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites
650623,158,0,45,56,44,0,2,105,39,1,49,1,BEND3P3;BEN domain containing 3 pseudogene 3,-,-,-,K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
65065,0,4,0,34,97,83,2,0,78,0,0,0,NBEAL1;neurobeachin-like 1,-,-,-,K14556//Ribosome biogenesis in eukaryotes
650655,0,0,13,0,0,27,42,0,50,0,5,0,"ABCA17P;ATP-binding cassette, sub-family A (ABC1), member 17, pseudogene",-,-,-,K05643//ABC transporters
6507,0,0,0,0,0,38,8,0,19,69,0,0,"SLC1A3;solute carrier family 1 (glial high affinity glutamate transporter), member 3",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0043205//fibril;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0042995//cell projection,GO:0007268//synaptic transmission;GO:0051938//L-glutamate import;GO:0009611//response to wounding;GO:0009416//response to light stimulus;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0006537//glutamate biosynthetic process;GO:0031223//auditory behavior;GO:0009449//gamma-aminobutyric acid biosynthetic process;GO:0001504//neurotransmitter uptake;GO:0055085//transmembrane transport;GO:0050885//neuromuscular process controlling balance;GO:0006811//ion transport;GO:0050806//positive regulation of synaptic transmission;GO:0070779//D-aspartate import;GO:0046677//response to antibiotic;GO:0021545//cranial nerve development;GO:0042493//response to drug;GO:0007605//sensory perception of sound,GO:0005314//high-affinity glutamate transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0016595//glutamate binding,K05614//Glutamatergic synapse
65078,0,0,0,0,0,0,0,0,21,0,0,0,RTN4R;reticulon 4 receptor,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0031225//anchored component of membrane,GO:0007409//axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0050770//regulation of axonogenesis;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0004872//receptor activity;GO:0005515//protein binding,-
650794,0,85,57,134,78,0,0,0,0,0,67,0,MIPEPP3;mitochondrial intermediate peptidase pseudogene 3,-,-,-,-
6508,0,0,0,0,0,7,27,0,74,173,9,0,"SLC4A3;solute carrier family 4 (anion exchanger), member 3",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport;GO:0051453//regulation of intracellular pH;GO:0006811//ion transport;GO:0006810//transport,GO:0005452//inorganic anion exchanger activity,-
65080,0,0,0,1,2,0,0,0,6,0,0,0,MRPL44;mitochondrial ribosomal protein L44,GO:0005840//ribosome;GO:0005739//mitochondrion,"GO:0070125//mitochondrial translational elongation;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006396//RNA processing",GO:0004525//ribonuclease III activity;GO:0044822//poly(A) RNA binding,K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
65082,0,0,0,3,4,9,2,0,0,0,3,482,VPS33A;vacuolar protein sorting 33 homolog A (S. cerevisiae),GO:0048471//perinuclear region of cytoplasm;GO:0030897//HOPS complex;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005769//early endosome;GO:0005770//late endosome,GO:0032418//lysosome localization;GO:0015031//protein transport;GO:0048070//regulation of developmental pigmentation;GO:0030220//platelet formation;GO:0032400//melanosome localization;GO:0016192//vesicle-mediated transport;GO:0006904//vesicle docking involved in exocytosis,GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K12479//Endocytosis
65083,0,18,0,0,1,40,0,1,0,0,0,0,NOL6;nucleolar protein 6 (RNA-associated),GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0000794//condensed nuclear chromosome,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,K14544//Ribosome biogenesis in eukaryotes
65084,50,12,0,19,28,0,0,47,54,137,0,0,TMEM135;transmembrane protein 135,GO:0016021//integral component of membrane;GO:0005777//peroxisome,GO:0007031//peroxisome organization,-,K02354//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Wnt signaling pathway;HTLV-I infection;K11447//Transcriptional misregulation in cancer
6509,0,0,36,16,16,0,0,0,114,0,11,0,"SLC1A4;solute carrier family 1 (glutamate/neutral amino acid transporter), member 4",GO:0005815//microtubule organizing center;GO:0005887//integral component of plasma membrane;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0042470//melanosome;GO:0043025//neuronal cell body;GO:0005813//centrosome,"GO:0015808//L-alanine transport;GO:0006821//chloride transport;GO:0034589//hydroxyproline transport;GO:0055085//transmembrane transport;GO:0015825//L-serine transport;GO:0006811//ion transport;GO:0035249//synaptic transmission, glutamatergic;GO:1902476//chloride transmembrane transport;GO:0006865//amino acid transport;GO:0006835//dicarboxylic acid transport;GO:0006868//glutamine transport;GO:0015811//L-cystine transport;GO:0035524//proline transmembrane transport;GO:0015826//threonine transport;GO:0050890//cognition;GO:0015824//proline transport",GO:0034590//L-hydroxyproline transmembrane transporter activity;GO:0015194//L-serine transmembrane transporter activity;GO:0015195//L-threonine transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0015180//L-alanine transmembrane transporter activity;GO:0005254//chloride channel activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0017153//sodium:dicarboxylate symporter activity;GO:0015193//L-proline transmembrane transporter activity,-
65094,65,149,54,57,214,13,0,429,46,1,181,115,JMJD4;jumonji domain containing 4,-,-,GO:0005515//protein binding,-
65095,2,134,30,72,181,0,12,60,61,0,22,13,KRI1;KRI1 homolog (S. cerevisiae),GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
651,0,0,0,0,0,31,1,0,11,0,11,0,BMP3;bone morphogenetic protein 3,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0001503//ossification;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001501//skeletal system development;GO:0007267//cell-cell signaling;GO:0040007//growth;GO:0051216//cartilage development,GO:0070700//BMP receptor binding;GO:0005102//receptor binding;GO:0008083//growth factor activity;GO:0005125//cytokine activity,-
6510,0,31,0,2,15,7,0,42,7,0,69,0,"SLC1A5;solute carrier family 1 (neutral amino acid transporter), member 5",GO:0042470//melanosome;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006835//dicarboxylic acid transport;GO:0006868//glutamine transport;GO:0009615//response to virus;GO:0055085//transmembrane transport;GO:0015825//L-serine transport;GO:0006811//ion transport;GO:0015804//neutral amino acid transport;GO:0006860//extracellular amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport,GO:0015194//L-serine transmembrane transporter activity;GO:0005515//protein binding;GO:0017153//sodium:dicarboxylate symporter activity;GO:0015186//L-glutamine transmembrane transporter activity;GO:0001618//virus receptor activity;GO:0015175//neutral amino acid transmembrane transporter activity;GO:0004872//receptor activity,K05616//Protein digestion and absorption
65108,0,70,1,28,176,0,0,0,14,0,12,0,MARCKSL1;MARCKS-like 1,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0008284//positive regulation of cell proliferation,GO:0005516//calmodulin binding;GO:0003779//actin binding,K13536//Fc gamma R-mediated phagocytosis;Leishmaniasis
65109,0,0,0,0,8,44,24,0,17,0,0,0,UPF3B;UPF3 regulator of nonsense transcripts homolog B (yeast),GO:0005829//cytosol;GO:0035145//exon-exon junction complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0031124//mRNA 3'-end processing;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0045727//positive regulation of translation;GO:0006406//mRNA export from nucleus",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0003729//mRNA binding,K14328//mRNA surveillance pathway;RNA transport
6511,65,0,0,0,0,15,4,0,20,0,4,0,"SLC1A6;solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0006811//ion transport;GO:0015810//aspartate transport;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport;GO:0042391//regulation of membrane potential;GO:0015813//L-glutamate transport,GO:0017153//sodium:dicarboxylate symporter activity;GO:0015183//L-aspartate transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity,K05617//Glutamatergic synapse
65110,5,0,0,5,44,10,0,34,26,0,0,0,UPF3A;UPF3 regulator of nonsense transcripts homolog A (yeast),GO:0035145//exon-exon junction complex;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0045727//positive regulation of translation;GO:0006913//nucleocytoplasmic transport;GO:0051028//mRNA transport",GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0003723//RNA binding,K14328//RNA transport;mRNA surveillance pathway
65117,0,0,0,0,28,11,24,0,28,0,0,0,RSRC2;arginine/serine-rich coiled-coil 2,-,-,GO:0044822//poly(A) RNA binding,-
6512,0,0,0,0,0,10,0,0,58,0,5,0,"SLC1A7;solute carrier family 1 (glutamate transporter), member 7",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006811//ion transport;GO:0015813//L-glutamate transport;GO:0055085//transmembrane transport;GO:0006835//dicarboxylic acid transport,GO:0017153//sodium:dicarboxylate symporter activity;GO:0005313//L-glutamate transmembrane transporter activity,K05618//Glutamatergic synapse
65121,0,0,0,0,0,0,0,0,10,0,0,0,PRAMEF1;PRAME family member 1,-,"GO:0008284//positive regulation of cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045596//negative regulation of cell differentiation;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process",GO:0042974//retinoic acid receptor binding,-
65122,0,0,0,0,0,19,0,0,28,0,0,0,PRAMEF2;PRAME family member 2,-,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0045596//negative regulation of cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0042974//retinoic acid receptor binding,-
65123,195,36,1,0,1,0,30,0,0,129,0,0,INTS3;integrator complex subunit 3,GO:0032039//integrator complex;GO:0070876//SOSS complex;GO:0005634//nucleus,GO:0007093//mitotic cell cycle checkpoint;GO:0006974//cellular response to DNA damage stimulus;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation;GO:0016180//snRNA processing,GO:0005515//protein binding,-
65124,99,0,0,26,9,8,0,0,0,0,0,0,SOWAHC;sosondowah ankyrin repeat domain family member C,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
65125,0,17,2,31,291,0,2,48,71,132,21,0,WNK1;WNK lysine deficient protein kinase 1,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0003084//positive regulation of systemic arterial blood pressure;GO:0018107//peptidyl-threonine phosphorylation;GO:0035556//intracellular signal transduction;GO:0090188//negative regulation of pancreatic juice secretion;GO:0006811//ion transport;GO:0050794//regulation of cellular process;GO:0048666//neuron development;GO:0006469//negative regulation of protein kinase activity;GO:0010923//negative regulation of phosphatase activity,GO:0004674//protein serine/threonine kinase activity;GO:0019902//phosphatase binding;GO:0004860//protein kinase inhibitor activity;GO:0019869//chloride channel inhibitor activity;GO:0005515//protein binding;GO:0005524//ATP binding,-
6513,97,0,0,0,0,0,0,26,17,138,0,0,"SLC2A1;solute carrier family 2 (facilitated glucose transporter), member 1",GO:0005911//cell-cell junction;GO:0016020//membrane;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005887//integral component of plasma membrane;GO:0030864//cortical actin cytoskeleton;GO:0005901//caveola;GO:0016323//basolateral plasma membrane;GO:0001939//female pronucleus;GO:0030496//midbody,GO:0042908//xenobiotic transport;GO:0055085//transmembrane transport;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0042149//cellular response to glucose starvation;GO:0015758//glucose transport;GO:0006766//vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0019852//L-ascorbic acid metabolic process;GO:0070837//dehydroascorbic acid transport;GO:0006970//response to osmotic stress;GO:0006461//protein complex assembly;GO:0005975//carbohydrate metabolic process,GO:0042802//identical protein binding;GO:0005355//glucose transmembrane transporter activity;GO:0033300//dehydroascorbic acid transporter activity;GO:0019900//kinase binding;GO:0042910//xenobiotic transporter activity;GO:0055056//D-glucose transmembrane transporter activity;GO:0005515//protein binding;GO:0043621//protein self-association,K07299//Renal cell carcinoma;Bile secretion;HTLV-I infection;Adipocytokine signaling pathway;Pathways in cancer
651302,0,0,0,0,0,15,0,0,0,0,0,0,ZNF192P1;zinc finger protein 192 pseudogene 1,-,-,-,-
6514,0,0,0,0,0,10,0,0,1,0,0,0,"SLC2A2;solute carrier family 2 (facilitated glucose transporter), member 2",GO:0005903//brush border;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0070837//dehydroascorbic acid transport;GO:0031018//endocrine pancreas development;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0035428//hexose transmembrane transport;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0015758//glucose transport;GO:0055085//transmembrane transport,GO:0005355//glucose transmembrane transporter activity;GO:0033300//dehydroascorbic acid transporter activity;GO:0055056//D-glucose transmembrane transporter activity,K07593//Carbohydrate digestion and absorption;Type II diabetes mellitus;Maturity onset diabetes of the young
651430,0,0,0,0,0,0,0,95,1,0,0,0,FLJ38576;uncharacterized LOC651430,-,-,-,-
6515,0,0,0,0,0,0,11,0,27,0,13,0,"SLC2A3;solute carrier family 2 (facilitated glucose transporter), member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0019852//L-ascorbic acid metabolic process;GO:0055085//transmembrane transport;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0005975//carbohydrate metabolic process;GO:0015758//glucose transport;GO:0006766//vitamin metabolic process,GO:0005355//glucose transmembrane transporter activity,-
6517,115,0,0,0,1,16,25,180,24,88,2,1,"SLC2A4;solute carrier family 2 (facilitated glucose transporter), member 4",GO:0005771//multivesicular body;GO:0042383//sarcolemma;GO:0012506//vesicle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane;GO:0032593//insulin-responsive compartment;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0030140//trans-Golgi network transport vesicle;GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0005905//coated pit,GO:0015758//glucose transport;GO:0032869//cellular response to insulin stimulus;GO:0050873//brown fat cell differentiation;GO:0045471//response to ethanol;GO:0061024//membrane organization;GO:0046323//glucose import;GO:0071470//cellular response to osmotic stress;GO:0010021//amylopectin biosynthetic process;GO:0055085//transmembrane transport;GO:0005975//carbohydrate metabolic process;GO:0042593//glucose homeostasis;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0005355//glucose transmembrane transporter activity;GO:0055056//D-glucose transmembrane transporter activity,K07191//Insulin signaling pathway;Adipocytokine signaling pathway;Type II diabetes mellitus
651746,0,0,1,0,0,11,17,0,6,0,6,0,ANKRD33B;ankyrin repeat domain 33B,-,-,-,K12460//Neurotrophin signaling pathway
6518,0,0,0,1,2,1,0,0,36,0,24,0,"SLC2A5;solute carrier family 2 (facilitated glucose/fructose transporter), member 5",GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0015755//fructose transport;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0015758//glucose transport;GO:0071332//cellular response to fructose stimulus,GO:0005353//fructose transmembrane transporter activity;GO:0005355//glucose transmembrane transporter activity,K08143//Carbohydrate digestion and absorption
6519,0,108,78,205,256,28,0,102,25,0,231,2,"SLC3A1;solute carrier family 3 (amino acid transporter heavy chain), member 1",GO:0005887//integral component of plasma membrane;GO:0005774//vacuolar membrane;GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0015802//basic amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0005975//carbohydrate metabolic process;GO:0006865//amino acid transport;GO:0055085//transmembrane transport;GO:0015811//L-cystine transport;GO:0006520//cellular amino acid metabolic process;GO:0006811//ion transport,GO:0046982//protein heterodimerization activity;GO:0043169//cation binding;GO:0005515//protein binding;GO:0015174//basic amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0015184//L-cystine transmembrane transporter activity;GO:0003824//catalytic activity,K14210//Protein digestion and absorption
652,0,0,0,0,0,12,36,25,18,0,0,0,BMP4;bone morphogenetic protein 4,GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0042326//negative regulation of phosphorylation;GO:0060686//negative regulation of prostatic bud formation;GO:0035993//deltoid tuberosity development;GO:0042476//odontogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0072101//specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002062//chondrocyte differentiation;GO:0021904//dorsal/ventral neural tube patterning;GO:0060395//SMAD protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0072001//renal system development;GO:0060449//bud elongation involved in lung branching;GO:0048286//lung alveolus development;GO:0002244//hematopoietic progenitor cell differentiation;GO:0003323//type B pancreatic cell development;GO:0043401//steroid hormone mediated signaling pathway;GO:2000007//negative regulation of metanephric comma-shaped body morphogenesis;GO:2000137//negative regulation of cell proliferation involved in heart morphogenesis;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0061047//positive regulation of branching involved in lung morphogenesis;GO:0060548//negative regulation of cell death;GO:0045786//negative regulation of cell cycle;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0051150//regulation of smooth muscle cell differentiation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0021537//telencephalon development;GO:0010159//specification of organ position;GO:0021978//telencephalon regionalization;GO:0032092//positive regulation of protein binding;GO:0010595//positive regulation of endothelial cell migration;GO:0060684//epithelial-mesenchymal cell signaling;GO:0030509//BMP signaling pathway;GO:0045839//negative regulation of mitosis;GO:0060363//cranial suture morphogenesis;GO:0003197//endocardial cushion development;GO:0001822//kidney development;GO:0035116//embryonic hindlimb morphogenesis;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043407//negative regulation of MAP kinase activity;GO:0045603//positive regulation of endothelial cell differentiation;GO:0071363//cellular response to growth factor stimulus;GO:0045778//positive regulation of ossification;GO:0043065//positive regulation of apoptotic process;GO:0048663//neuron fate commitment;GO:0001958//endochondral ossification;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0060197//cloacal septation;GO:0060113//inner ear receptor cell differentiation;GO:0045843//negative regulation of striated muscle tissue development;GO:0061155//pulmonary artery endothelial tube morphogenesis;GO:0030198//extracellular matrix organization;GO:0032331//negative regulation of chondrocyte differentiation;GO:0007281//germ cell development;GO:0072161//mesenchymal cell differentiation involved in kidney development;GO:0060433//bronchus development;GO:0021983//pituitary gland development;GO:0045669//positive regulation of osteoblast differentiation;GO:0030224//monocyte differentiation;GO:0030513//positive regulation of BMP signaling pathway;GO:0007224//smoothened signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0009791//post-embryonic development;GO:0009948//anterior/posterior axis specification;GO:0001823//mesonephros development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0000186//activation of MAPKK activity;GO:0030225//macrophage differentiation;GO:0061149//BMP signaling pathway involved in ureter morphogenesis;GO:0007182//common-partner SMAD protein phosphorylation;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0072097//negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway;GO:0050918//positive chemotaxis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0055020//positive regulation of cardiac muscle fiber development;GO:0060442//branching involved in prostate gland morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0070244//negative regulation of thymocyte apoptotic process;GO:0061036//positive regulation of cartilage development;GO:0001657//ureteric bud development;GO:0090184//positive regulation of kidney development;GO:0048745//smooth muscle tissue development;GO:0071893//BMP signaling pathway involved in nephric duct formation;GO:0072015//glomerular visceral epithelial cell development;GO:0002320//lymphoid progenitor cell differentiation;GO:0045606//positive regulation of epidermal cell differentiation;GO:0010453//regulation of cell fate commitment;GO:0045662//negative regulation of myoblast differentiation;GO:0072104//glomerular capillary formation;GO:0060503//bud dilation involved in lung branching;GO:0003130//BMP signaling pathway involved in heart induction;GO:0072192//ureter epithelial cell differentiation;GO:0032967//positive regulation of collagen biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0072205//metanephric collecting duct development;GO:0072125//negative regulation of glomerular mesangial cell proliferation;GO:0034504//protein localization to nucleus;GO:0061151//BMP signaling pathway involved in renal system segmentation;GO:0072200//negative regulation of mesenchymal cell proliferation involved in ureter development;GO:0007500//mesodermal cell fate determination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003014//renal system process;GO:0060440//trachea formation;GO:0003139//secondary heart field specification;GO:2000005//negative regulation of metanephric S-shaped body morphogenesis;GO:0072138//mesenchymal cell proliferation involved in ureteric bud development;GO:0042733//embryonic digit morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090194//negative regulation of glomerulus development;GO:0033085//negative regulation of T cell differentiation in thymus;GO:2000105//positive regulation of DNA-dependent DNA replication;GO:0030218//erythrocyte differentiation;GO:0060438//trachea development;GO:0072193//ureter smooth muscle cell differentiation;GO:0033088//negative regulation of immature T cell proliferation in thymus;GO:0060235//lens induction in camera-type eye;GO:0003279//cardiac septum development;GO:0035990//tendon cell differentiation;GO:0048392//intermediate mesodermal cell differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001649//osteoblast differentiation;GO:0030501//positive regulation of bone mineralization;GO:0060502//epithelial cell proliferation involved in lung morphogenesis;GO:0001843//neural tube closure;GO:0060272//embryonic skeletal joint morphogenesis;GO:0010942//positive regulation of cell death;GO:0060592//mammary gland formation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0060425//lung morphogenesis;GO:0090191//negative regulation of branching involved in ureteric bud morphogenesis",GO:0070700//BMP receptor binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K04662//Cytokine-cytokine receptor interaction;Pathways in cancer;Hedgehog signaling pathway;TGF-beta signaling pathway;Basal cell carcinoma
6520,0,0,0,1,0,0,0,0,0,0,9,0,"SLC3A2;solute carrier family 3 (amino acid transporter heavy chain), member 2",GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0043330//response to exogenous dsRNA;GO:0006811//ion transport;GO:0007596//blood coagulation;GO:0035725//sodium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0055085//transmembrane transport;GO:0016049//cell growth;GO:0006865//amino acid transport;GO:0005975//carbohydrate metabolic process;GO:0060356//leucine import;GO:0050900//leukocyte migration;GO:0015827//tryptophan transport,GO:0003725//double-stranded RNA binding;GO:0005432//calcium:sodium antiporter activity;GO:0044822//poly(A) RNA binding;GO:0043169//cation binding;GO:0005515//protein binding;GO:0003824//catalytic activity;GO:0015175//neutral amino acid transmembrane transporter activity,K06519//Protein digestion and absorption
6521,0,0,0,0,0,37,23,0,44,0,2,0,"SLC4A1;solute carrier family 4 (anion exchanger), member 1 (Diego blood group)",GO:0030863//cortical cytoskeleton;GO:0016323//basolateral plasma membrane;GO:0005887//integral component of plasma membrane;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030018//Z disc,GO:0044281//small molecule metabolic process;GO:0006821//chloride transport;GO:1902476//chloride transmembrane transport;GO:0006873//cellular ion homeostasis;GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006820//anion transport,GO:0030506//ankyrin binding;GO:0043495//protein anchor;GO:0015301//anion:anion antiporter activity;GO:0003779//actin binding;GO:0015106//bicarbonate transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005452//inorganic anion exchanger activity;GO:0015108//chloride transmembrane transporter activity;GO:0008509//anion transmembrane transporter activity;GO:0008022//protein C-terminus binding,K06573//Collecting duct acid secretion
65217,0,0,0,0,0,50,94,0,45,140,10,281,PCDH15;protocadherin-related 15,GO:0032420//stereocilium;GO:0001750//photoreceptor outer segment;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0050953//sensory perception of light stimulus;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007605//sensory perception of sound;GO:0050957//equilibrioception;GO:0045494//photoreceptor cell maintenance,GO:0005509//calcium ion binding,-
6522,173,0,0,0,2,33,0,1,13,0,24,0,"SLC4A2;solute carrier family 4 (anion exchanger), member 2",GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:1902476//chloride transmembrane transport;GO:0006811//ion transport;GO:0006820//anion transport;GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport,GO:0008509//anion transmembrane transporter activity;GO:0015108//chloride transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity,K13855//Bile secretion;Salivary secretion;Gastric acid secretion;Pancreatic secretion
65220,0,23,0,9,39,0,0,0,35,6,17,0,NADK;NAD kinase,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006741//NADP biosynthetic process;GO:0006767//water-soluble vitamin metabolic process;GO:0046034//ATP metabolic process;GO:0019674//NAD metabolic process;GO:0016310//phosphorylation;GO:0006766//vitamin metabolic process,GO:0005524//ATP binding;GO:0003951//NAD+ kinase activity;GO:0046872//metal ion binding,K00858//Histidine metabolism;Metabolic pathways;Nicotinate and nicotinamide metabolism
652276,0,32,0,0,0,1,0,0,24,0,0,0,LOC652276;potassium channel tetramerization domain containing 5 pseudogene,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
6523,0,1,0,0,0,1,0,0,80,64,0,0,"SLC5A1;solute carrier family 5 (sodium/glucose cotransporter), member 1",GO:0016324//apical plasma membrane;GO:0005911//cell-cell junction;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane,GO:0044281//small molecule metabolic process;GO:0050892//intestinal absorption;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0015758//glucose transport;GO:0005975//carbohydrate metabolic process,GO:0005515//protein binding;GO:0005412//glucose:sodium symporter activity,K14158//Carbohydrate digestion and absorption;Bile secretion;Mineral absorption
6524,0,0,213,77,81,0,0,645,155,0,169,1,"SLC5A2;solute carrier family 5 (sodium/glucose cotransporter), member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0015758//glucose transport;GO:0005975//carbohydrate metabolic process;GO:0006810//transport,GO:0005362//low-affinity glucose:sodium symporter activity,-
65243,0,0,0,0,0,30,23,0,43,0,0,0,ZFP69B;ZFP69 zinc finger protein B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
65244,0,0,0,0,0,26,28,69,35,0,2,0,"SPATS2;spermatogenesis associated, serine-rich 2",GO:0005737//cytoplasm,-,GO:0044822//poly(A) RNA binding,K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
65249,0,0,15,0,23,3,21,0,4,1,0,0,"ZSWIM4;zinc finger, SWIM-type containing 4",-,-,GO:0008270//zinc ion binding,-
6525,49,0,0,10,9,0,64,5,28,0,4,0,SMTN;smoothelin,GO:0015629//actin cytoskeleton;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:0007517//muscle organ development;GO:0006939//smooth muscle contraction,GO:0008307//structural constituent of muscle;GO:0003779//actin binding,K05699//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Focal adhesion;Amoebiasis;Adherens junction;K06115//Tight junction
65250,0,0,1,18,48,17,47,68,67,0,6,0,C5orf42;chromosome 5 open reading frame 42,GO:0016021//integral component of membrane,-,-,-
65251,0,1,0,46,103,0,0,0,23,0,0,379,ZNF649;zinc finger protein 649,GO:0005634//nucleus;GO:0005615//extracellular space,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
65258,0,0,0,11,0,24,0,0,4,38,39,0,MPPE1;metallophosphoesterase 1,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0070971//endoplasmic reticulum exit site;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0016021//integral component of membrane;GO:0005801//cis-Golgi network,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006506//GPI anchor biosynthetic process,GO:0034235//GPI anchor binding;GO:0030145//manganese ion binding;GO:0008081//phosphoric diester hydrolase activity,K11447//Transcriptional misregulation in cancer;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
6526,0,0,0,0,0,0,15,16,51,1,0,254,"SLC5A3;solute carrier family 5 (sodium/myo-inositol cotransporter), member 3",GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006020//inositol metabolic process;GO:0043576//regulation of respiratory gaseous exchange;GO:0006810//transport;GO:0007422//peripheral nervous system development;GO:0006814//sodium ion transport;GO:0015798//myo-inositol transport;GO:0055085//transmembrane transport,GO:0005367//myo-inositol:sodium symporter activity,-
65260,0,0,0,0,64,47,0,0,1,0,12,0,COA7;cytochrome c oxidase assembly factor 7 (putative),GO:0005758//mitochondrial intermembrane space,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
65263,0,0,0,0,0,14,0,0,32,127,6,0,PYCRL;pyrroline-5-carboxylate reductase-like,-,GO:0055114//oxidation-reduction process;GO:0055129//L-proline biosynthetic process,GO:0042802//identical protein binding;GO:0004735//pyrroline-5-carboxylate reductase activity,"K00286//Arginine and proline metabolism;Two-component system;Metabolic pathways;Propanoate metabolism;Pyruvate metabolism;Methane metabolism;Taurine and hypotaurine metabolism;Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments"
65264,11,28,0,7,185,0,21,0,17,0,0,0,UBE2Z;ubiquitin-conjugating enzyme E2Z,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0016567//protein ubiquitination;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K10585//Ubiquitin mediated proteolysis
65265,0,18,19,21,134,0,0,0,29,0,0,0,C8orf33;chromosome 8 open reading frame 33,-,-,-,K07987//Natural killer cell mediated cytotoxicity
65266,186,4,0,9,21,9,0,73,30,0,50,313,WNK4;WNK lysine deficient protein kinase 4,GO:0005737//cytoplasm;GO:0005923//tight junction,GO:0070294//renal sodium ion absorption;GO:0006821//chloride transport;GO:0050801//ion homeostasis;GO:0072156//distal tubule morphogenesis;GO:0008104//protein localization;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0090188//negative regulation of pancreatic juice secretion;GO:0006811//ion transport;GO:0050794//regulation of cellular process,GO:0005524//ATP binding;GO:0019869//chloride channel inhibitor activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
65267,0,33,0,27,85,30,38,73,122,0,15,0,WNK3;WNK lysine deficient protein kinase 3,GO:0005912//adherens junction;GO:0005737//cytoplasm;GO:0005923//tight junction,GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010765//positive regulation of sodium ion transport;GO:0046777//protein autophosphorylation;GO:2000021//regulation of ion homeostasis;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0051928//positive regulation of calcium ion transport;GO:2000688//positive regulation of rubidium ion transmembrane transporter activity;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0035556//intracellular signal transduction;GO:2000682//positive regulation of rubidium ion transport;GO:0043066//negative regulation of apoptotic process;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0019869//chloride channel inhibitor activity;GO:0004672//protein kinase activity;GO:0005515//protein binding,-
65268,0,0,0,10,10,33,14,66,24,2,8,0,WNK2;WNK lysine deficient protein kinase 2,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000651//positive regulation of sodium ion transmembrane transporter activity;GO:2000021//regulation of ion homeostasis;GO:0046777//protein autophosphorylation;GO:0035556//intracellular signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
6527,67,51,0,0,37,0,0,0,50,0,12,0,"SLC5A4;solute carrier family 5 (glucose activated ion channel), member 4",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0008643//carbohydrate transport;GO:0006814//sodium ion transport,GO:0015293//symporter activity,-
6528,0,0,0,0,0,24,40,0,33,0,3,0,"SLC5A5;solute carrier family 5 (sodium/iodide cotransporter), member 5",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0031982//vesicle;GO:0005634//nucleus,GO:0071320//cellular response to cAMP;GO:0071371//cellular response to gonadotropin stimulus;GO:0006810//transport;GO:0006811//ion transport;GO:0034641//cellular nitrogen compound metabolic process;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0015705//iodide transport;GO:0044281//small molecule metabolic process;GO:0006590//thyroid hormone generation,GO:0008507//sodium:iodide symporter activity;GO:0015111//iodide transmembrane transporter activity,-
6529,0,0,0,0,0,0,9,33,50,0,0,0,"SLC6A1;solute carrier family 6 (neurotransmitter transporter), member 1",GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0030424//axon;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0051260//protein homooligomerization;GO:0009744//response to sucrose;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0009636//response to toxic substance;GO:0042220//response to cocaine;GO:0051939//gamma-aminobutyric acid import;GO:0010288//response to lead ion;GO:0055085//transmembrane transport;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0007269//neurotransmitter secretion;GO:0007612//learning;GO:0032355//response to estradiol;GO:0006810//transport;GO:0051592//response to calcium ion;GO:0014074//response to purine-containing compound;GO:0007268//synaptic transmission",GO:0005328//neurotransmitter:sodium symporter activity;GO:0005332//gamma-aminobutyric acid:sodium symporter activity,K05034//GABAergic synapse
652968,0,0,0,0,1,0,0,0,0,0,0,0,GATSL3;GATS protein-like 3,-,-,-,-
652972,0,0,0,0,0,0,0,0,16,0,5,0,"LRRC37A5P;leucine rich repeat containing 37, member A5, pseudogene",-,-,-,-
652991,0,0,0,0,0,4,0,1,34,0,5,0,SKOR2;SKI family transcriptional corepressor 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045880//positive regulation of smoothened signaling pathway;GO:0021936//regulation of cerebellar granule cell precursor proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021702//cerebellar Purkinje cell differentiation;GO:0048814//regulation of dendrite morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0030514//negative regulation of BMP signaling pathway",GO:0003714//transcription corepressor activity;GO:0046332//SMAD binding;GO:0042826//histone deacetylase binding,-
653,0,0,0,0,0,23,9,0,20,112,11,0,BMP5;bone morphogenetic protein 5,GO:0005615//extracellular space;GO:0031988//membrane-bounded vesicle,GO:0001501//skeletal system development;GO:0003323//type B pancreatic cell development;GO:1900006//positive regulation of dendrite development;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway;GO:0040007//growth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071676//negative regulation of mononuclear cell migration;GO:0010894//negative regulation of steroid biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0050679//positive regulation of epithelial cell proliferation;GO:0007389//pattern specification process;GO:2000105//positive regulation of DNA-dependent DNA replication;GO:0032348//negative regulation of aldosterone biosynthetic process;GO:2000065//negative regulation of cortisol biosynthetic process;GO:0001503//ossification;GO:0051216//cartilage development;GO:0030539//male genitalia development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation,GO:0070700//BMP receptor binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity,K04663//Hedgehog signaling pathway;Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
6530,57,0,0,0,0,5,0,14,43,0,18,0,"SLC6A2;solute carrier family 6 (neurotransmitter transporter), member 2",GO:0043005//neuron projection;GO:0045121//membrane raft;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006836//neurotransmitter transport;GO:0015844//monoamine transport;GO:0042493//response to drug;GO:0048265//response to pain;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport;GO:0015874//norepinephrine transport;GO:0006810//transport,GO:0005515//protein binding;GO:0043014//alpha-tubulin binding;GO:0008504//monoamine transmembrane transporter activity;GO:0048487//beta-tubulin binding;GO:0005334//norepinephrine:sodium symporter activity,-
653061,2,0,0,0,2,26,0,0,25,0,8,0,"GOLGA8S;golgin A8 family, member S",-,-,-,-
653073,75,0,0,2,0,25,3,0,15,4,7,0,"GOLGA8J;golgin A8 family, member J",GO:0005794//Golgi apparatus,-,-,K12478//Tuberculosis;Endocytosis;Phagosome
653075,0,0,0,0,0,0,16,31,27,0,2,0,"GOLGA8T;golgin A8 family, member T",-,-,-,K12478//Phagosome;Endocytosis;Tuberculosis;K06102//Tight junction
6531,0,0,0,0,0,12,17,0,35,1,11,274,"SLC6A3;solute carrier family 6 (neurotransmitter transporter), member 3",GO:0030424//axon;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane,GO:0060134//prepulse inhibition;GO:0007608//sensory perception of smell;GO:0021984//adenohypophysis development;GO:0055085//transmembrane transport;GO:0045471//response to ethanol;GO:0042493//response to drug;GO:0008219//cell death;GO:0015872//dopamine transport;GO:0007626//locomotory behavior;GO:0010039//response to iron ion;GO:0042136//neurotransmitter biosynthetic process;GO:0042220//response to cocaine;GO:0015844//monoamine transport;GO:0006836//neurotransmitter transport;GO:0042053//regulation of dopamine metabolic process;GO:0042420//dopamine catabolic process;GO:0007268//synaptic transmission;GO:0007568//aging;GO:0040018//positive regulation of multicellular organism growth;GO:0007595//lactation;GO:0051591//response to cAMP;GO:0042416//dopamine biosynthetic process;GO:0035094//response to nicotine,GO:0032403//protein complex binding;GO:0005330//dopamine:sodium symporter activity;GO:0047485//protein N-terminus binding;GO:0008144//drug binding;GO:0035240//dopamine binding;GO:0008504//monoamine transmembrane transporter activity;GO:0002020//protease binding;GO:0005102//receptor binding;GO:0005329//dopamine transmembrane transporter activity;GO:0005515//protein binding,K05036//Alcoholism;Cocaine addiction;Dopaminergic synapse;Amphetamine addiction;Parkinson's disease
653113,32,0,0,0,0,0,12,0,20,0,0,0,"FAM86FP;family with sequence similarity 86, member A pseudogene",-,-,-,K03842//Metabolic pathways;Various types of N-glycan biosynthesis;N-Glycan biosynthesis
653121,0,0,0,0,14,0,16,0,41,0,0,0,ZBTB8A;zinc finger and BTB domain containing 8A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
653125,0,1,0,0,0,0,1,53,13,2,0,0,"GOLGA8K;golgin A8 family, member K",GO:0005794//Golgi apparatus,-,-,K12478//Phagosome;Endocytosis;Tuberculosis
653140,0,0,0,0,0,0,0,0,7,0,13,0,"FAM228A;family with sequence similarity 228, member A",-,-,-,-
653145,0,0,2,0,0,0,1,0,0,0,0,0,ANXA8;annexin A8,GO:0031902//late endosome membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0016197//endosomal transport;GO:0007032//endosome organization;GO:0007596//blood coagulation;GO:1900138//negative regulation of phospholipase A2 activity,"GO:0051015//actin filament binding;GO:0005509//calcium ion binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005544//calcium-dependent phospholipid binding",-
653149,0,0,0,0,0,1,5,1,0,55,1,0,"NBPF6;neuroblastoma breakpoint family, member 6",GO:0005737//cytoplasm,-,-,-
653160,0,0,0,0,0,0,0,0,24,0,0,0,LOC653160;uncharacterized LOC653160,GO:0016021//integral component of membrane,-,-,-
653162,20,0,0,8,1,0,0,0,0,0,0,0,RPSAP9;ribosomal protein SA pseudogene 9,-,-,-,K02998//Ribosome
653188,0,0,0,0,0,0,13,1,7,0,0,0,"GUSBP3;glucuronidase, beta pseudogene 3",-,-,-,K01195//Drug metabolism - other enzymes;Lysosome;Starch and sucrose metabolism;Glycosaminoglycan degradation;Pentose and glucuronate interconversions;Metabolic pathways;Porphyrin and chlorophyll metabolism
653190,0,1,0,0,0,10,1,0,0,0,6,0,"ABCC6P1;ATP-binding cassette, sub-family C, member 6 pseudogene 1 (functional)",-,-,-,K05669//ABC transporters
653192,0,0,0,0,0,0,0,0,30,0,0,0,TRIM43B;tripartite motif containing 43B,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
6532,1,0,0,13,16,29,4,61,51,0,0,1,"SLC6A4;solute carrier family 6 (neurotransmitter transporter), member 4",GO:0045121//membrane raft;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0005887//integral component of plasma membrane,"GO:0051260//protein homooligomerization;GO:0051259//protein oligomerization;GO:0042493//response to drug;GO:0009636//response to toxic substance;GO:0015844//monoamine transport;GO:0048854//brain morphogenesis;GO:0051610//serotonin uptake;GO:0045665//negative regulation of neuron differentiation;GO:0042713//sperm ejaculation;GO:0042310//vasoconstriction;GO:0010628//positive regulation of gene expression;GO:0055085//transmembrane transport;GO:0045787//positive regulation of cell cycle;GO:0007613//memory;GO:0032355//response to estradiol;GO:0021941//negative regulation of cerebellar granule cell precursor proliferation;GO:0071300//cellular response to retinoic acid;GO:0001666//response to hypoxia;GO:0035176//social behavior;GO:0032227//negative regulation of synaptic transmission, dopaminergic;GO:0007584//response to nutrient;GO:0071321//cellular response to cGMP;GO:0007623//circadian rhythm;GO:0021794//thalamus development;GO:0006837//serotonin transport;GO:0046621//negative regulation of organ growth",GO:0050998//nitric-oxide synthase binding;GO:0005335//serotonin:sodium symporter activity;GO:0017137//Rab GTPase binding;GO:0008504//monoamine transmembrane transporter activity;GO:0017075//syntaxin-1 binding;GO:0017022//myosin binding;GO:0019811//cocaine binding;GO:0051015//actin filament binding;GO:0015222//serotonin transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K05037//Serotonergic synapse
653238,0,0,0,0,0,0,14,0,0,0,0,0,"GTF2H2B;general transcription factor IIH, polypeptide 2B (pseudogene)",-,-,-,K03142//Nucleotide excision repair;Basal transcription factors
653247,0,0,0,0,0,0,0,1,0,0,0,0,PRB2;proline-rich protein BstNI subfamily 2,GO:0005576//extracellular region,-,-,K13911//Salivary secretion
653269,0,0,0,0,0,0,1,5,1,0,0,0,"POTEI;POTE ankyrin domain family, member I",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0001895//retina homeostasis,-,K05692//Bacterial invasion of epithelial cells;Tight junction;Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Focal adhesion;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Phototransduction - fly;Adherens junction
653275,0,0,0,0,0,0,0,0,2,0,0,0,"CFC1B;cripto, FRL-1, cryptic family 1B",GO:0005576//extracellular region,GO:0007369//gastrulation,-,-
6533,83,0,0,0,0,37,1,77,34,47,21,0,"SLC6A6;solute carrier family 6 (neurotransmitter transporter), member 6",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006836//neurotransmitter transport;GO:0006520//cellular amino acid metabolic process;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006810//transport;GO:0015734//taurine transport;GO:0006865//amino acid transport,GO:0005369//taurine:sodium symporter activity;GO:0030977//taurine binding;GO:0005328//neurotransmitter:sodium symporter activity,K05039//GABAergic synapse
653308,0,0,0,0,0,0,0,0,2,0,0,0,ASAH2B;N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B,-,-,-,K12349//Sphingolipid metabolism;Metabolic pathways
653319,116,15,0,0,10,0,33,65,13,0,53,0,KIAA0895L;KIAA0895-like,-,-,-,-
653333,0,1,0,0,1,0,0,4,23,0,47,0,"FAM86B2;family with sequence similarity 86, member B2",-,-,-,K00884//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
653361,92,0,0,0,0,0,0,0,0,0,0,0,NCF1;neutrophil cytosolic factor 1,GO:0019898//extrinsic component of membrane;GO:0043025//neuronal cell body;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0043020//NADPH oxidase complex;GO:0032010//phagolysosome;GO:0005791//rough endoplasmic reticulum;GO:0005829//cytosol,"GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045087//innate immune response;GO:0006691//leukotriene metabolic process;GO:0008283//cell proliferation;GO:0070947//neutrophil mediated killing of fungus;GO:0050665//hydrogen peroxide biosynthetic process;GO:0006801//superoxide metabolic process;GO:0045730//respiratory burst;GO:0002679//respiratory burst involved in defense response;GO:0051701//interaction with host;GO:0006954//inflammatory response;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0090382//phagosome maturation;GO:0006612//protein targeting to membrane;GO:0042554//superoxide anion generation;GO:0055114//oxidation-reduction process;GO:0006968//cellular defense response;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0070946//neutrophil mediated killing of gram-positive bacterium;GO:0001878//response to yeast;GO:0045986//negative regulation of smooth muscle contraction","GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0016175//superoxide-generating NADPH oxidase activity;GO:0035091//phosphatidylinositol binding;GO:0009055//electron carrier activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",K08011//Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Leishmaniasis;Chemokine signaling pathway;Osteoclast differentiation;Phagosome
653390,0,0,0,0,0,8,42,0,36,0,0,0,RRN3P2;RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2,-,-,-,-
653399,0,0,0,0,7,0,0,0,1,0,0,0,GSTTP2;glutathione S-transferase theta pseudogene 2,-,-,-,K00799//Prostate cancer;Glutathione metabolism;Metabolism of xenobiotics by cytochrome P450;Pathways in cancer;Drug metabolism - cytochrome P450
6534,0,0,0,0,0,0,11,13,24,0,0,0,"SLC6A7;solute carrier family 6 (neurotransmitter transporter), member 7",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0015824//proline transport;GO:0006810//transport;GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0005328//neurotransmitter:sodium symporter activity,-
653404,0,0,0,0,0,1,0,0,7,0,0,0,FOXD4L6;forkhead box D4-like 6,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
653427,0,0,0,0,0,0,0,2,6,0,0,0,FOXD4L5;forkhead box D4-like 5,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
653437,0,0,0,0,0,0,0,0,1,50,0,0,AQP12B;aquaporin 12B,GO:0016021//integral component of membrane,GO:0006810//transport,GO:0005215//transporter activity,-
653479,0,0,0,0,0,0,0,0,1,0,3,0,MRPL45P2;mitochondrial ribosomal protein L45 pseudogene 2,-,-,-,K11447//Transcriptional misregulation in cancer
653483,77,27,0,1,60,34,0,2,0,0,72,0,MLLT4-AS1;MLLT4 antisense RNA 1 (head to head),-,-,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
653489,99,0,0,1,0,3,3,0,30,0,0,2,RGPD3;RANBP2-like and GRIP domain containing 3,-,GO:0000042//protein targeting to Golgi,-,K12172//RNA transport
6535,0,38,0,0,1,9,0,0,50,0,21,0,"SLC6A8;solute carrier family 6 (neurotransmitter transporter), member 8",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006600//creatine metabolic process;GO:0006810//transport;GO:1902598//creatine transmembrane transport;GO:0034641//cellular nitrogen compound metabolic process;GO:0006936//muscle contraction;GO:0006814//sodium ion transport;GO:0006836//neurotransmitter transport;GO:0044281//small molecule metabolic process,GO:0005328//neurotransmitter:sodium symporter activity;GO:0005309//creatine:sodium symporter activity,K05039//GABAergic synapse
653509,0,0,0,0,0,0,0,0,5,0,0,0,SFTPA1;surfactant protein A1,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix,GO:0007585//respiratory gaseous exchange;GO:0006869//lipid transport,GO:0005319//lipid transporter activity;GO:0030246//carbohydrate binding,K10067//Phagosome;Pertussis
653513,0,0,0,0,0,0,0,1,0,0,0,0,LOC653513;phosphodiesterase 4D interacting protein pseudogene,-,-,-,-
653519,0,0,0,0,0,41,20,0,0,0,0,6,GPR89A;G protein-coupled receptor 89A,GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0030660//Golgi-associated vesicle membrane,GO:0044070//regulation of anion transport;GO:0051452//intracellular pH reduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0015031//protein transport;GO:0034765//regulation of ion transmembrane transport;GO:0007165//signal transduction;GO:0006811//ion transport,GO:0004871//signal transducer activity;GO:0008308//voltage-gated anion channel activity,-
653567,0,0,0,0,0,0,16,0,0,0,2,0,TMEM236;transmembrane protein 236,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K06560//Tuberculosis;Phagosome
653583,0,0,1,0,6,15,3,0,13,0,7,0,"PHLDB3;pleckstrin homology-like domain, family B, member 3",-,-,GO:0019899//enzyme binding,-
6536,44,0,0,6,20,0,22,0,62,0,21,0,"SLC6A9;solute carrier family 6 (neurotransmitter transporter, glycine), member 9",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006810//transport;GO:0003333//amino acid transmembrane transport;GO:0015816//glycine transport;GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0015375//glycine:sodium symporter activity;GO:0005328//neurotransmitter:sodium symporter activity,-
653602,0,0,0,0,0,0,0,0,0,0,8,0,LOC653602;uncharacterized LOC653602,-,-,-,-
653604,0,0,0,0,0,0,0,0,0,0,7,0,"HIST2H3D;histone cluster 2, H3d",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0007596//blood coagulation,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,K11253//Systemic lupus erythematosus;Transcriptional misregulation in cancer;Alcoholism
653635,0,0,0,0,0,0,0,0,1,0,0,0,WASH7P;WAS protein family homolog 7 pseudogene,-,-,-,-
653641,1,0,0,0,0,0,13,0,9,1,0,0,"GOLGA6C;golgin A6 family, member C",GO:0005794//Golgi apparatus,-,-,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K12478//Endocytosis;Phagosome;Tuberculosis
653643,0,0,0,0,0,6,0,0,7,0,0,0,"GOLGA6D;golgin A6 family, member D",GO:0005794//Golgi apparatus,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K12478//Phagosome;Endocytosis;Tuberculosis
653645,0,0,0,0,0,35,0,0,21,0,0,0,TBC1D3P1-DHX40P1;TBC1D3P1-DHX40P1 readthrough transcribed pseudogene,-,-,-,K12815//Spliceosome
653653,0,0,0,0,1,0,0,0,0,0,0,0,"LOC653653;adaptor-related protein complex 1, sigma 2 subunit pseudogene",-,-,-,K12394//Lysosome
653656,0,0,0,0,0,0,0,0,0,0,0,2,MBD3L4;methyl-CpG binding domain protein 3-like 4,-,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
653657,0,0,0,0,0,0,0,59,0,0,0,0,MBD3L3;methyl-CpG binding domain protein 3-like 3,-,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
653677,0,0,0,5,29,0,1,0,11,0,43,0,"SEC1P;secretory blood group 1, pseudogene",-,-,-,K00718//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
653691,0,0,0,0,2,0,1,1,18,0,39,0,"FAM115D;family with sequence similarity 139, member B",-,-,-,-
653712,0,1,28,0,19,0,0,0,0,0,1,0,LOC653712;intraflagellar transport 122 homolog (Chlamydomonas) pseudogene,-,-,-,-
653720,58,0,0,0,0,0,30,2,8,6,18,0,"GOLGA8M;golgin A8 family, member M",GO:0005794//Golgi apparatus,-,-,K12478//Tuberculosis;Phagosome;Endocytosis;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
653781,8,1,36,17,10,0,0,3,11,0,56,0,"POTEJ;POTE ankyrin domain family, member J",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0001895//retina homeostasis,-,K05692//Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection;Pathogenic Escherichia coli infection;Gastric acid secretion;Vibrio cholerae infection;Focal adhesion;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Dilated cardiomyopathy;Shigellosis;Leukocyte transendothelial migration;Tight junction;Bacterial invasion of epithelial cells
653784,0,0,0,0,0,0,0,0,32,0,1,0,MZT2A;mitotic spindle organizing protein 2A,GO:0008274//gamma-tubulin ring complex;GO:0005819//spindle;GO:0005813//centrosome,-,-,-
653786,0,0,0,0,0,0,0,0,0,0,4,0,LOC653786;otoancorin pseudogene,-,-,-,-
6538,0,0,0,0,0,0,0,0,23,0,0,0,"SLC6A11;solute carrier family 6 (neurotransmitter transporter), member 11",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0042995//cell projection;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,GO:0015812//gamma-aminobutyric acid transport;GO:0042493//response to drug;GO:0007420//brain development;GO:0055085//transmembrane transport;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission,GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0042165//neurotransmitter binding;GO:0005328//neurotransmitter:sodium symporter activity,K05039//GABAergic synapse
653808,22,0,0,0,0,4,0,0,0,0,0,0,ZG16;zymogen granule protein 16,GO:0031012//extracellular matrix;GO:0060205//cytoplasmic membrane-bounded vesicle lumen;GO:0005578//proteinaceous extracellular matrix;GO:0042589//zymogen granule membrane;GO:0005796//Golgi lumen,GO:0015031//protein transport,GO:0030246//carbohydrate binding,-
653820,0,0,0,0,0,0,0,0,9,0,0,0,"FAM72B;family with sequence similarity 72, member B",-,-,-,-
653857,0,75,0,17,94,0,0,115,28,0,99,0,ACTR3C;ARP3 actin-related protein 3 homolog C (yeast),GO:0070062//extracellular vesicular exosome,-,GO:0005524//ATP binding;GO:0003779//actin binding,K05692//Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Influenza A;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Adherens junction;Phototransduction - fly;Viral myocarditis;K12314//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction;K12315//Vascular smooth muscle contraction
6539,1,0,0,0,0,4,0,134,13,0,0,0,"SLC6A12;solute carrier family 6 (neurotransmitter transporter), member 12",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0009992//cellular water homeostasis;GO:0006810//transport;GO:0015812//gamma-aminobutyric acid transport;GO:0006811//ion transport;GO:0071474//cellular hyperosmotic response;GO:0006865//amino acid transport;GO:0010033//response to organic substance,GO:0005328//neurotransmitter:sodium symporter activity;GO:0005332//gamma-aminobutyric acid:sodium symporter activity,K05039//GABAergic synapse
654,0,0,20,6,0,33,0,62,29,0,16,0,BMP6;bone morphogenetic protein 6,GO:0005737//cytoplasm;GO:0031988//membrane-bounded vesicle;GO:0005615//extracellular space,GO:0014823//response to activity;GO:0030509//BMP signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation;GO:0001654//eye development;GO:0006955//immune response;GO:0030539//male genitalia development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0051216//cartilage development;GO:0001822//kidney development;GO:2000860//positive regulation of aldosterone secretion;GO:0040007//growth;GO:0003323//type B pancreatic cell development;GO:0001501//skeletal system development;GO:0030501//positive regulation of bone mineralization;GO:0045666//positive regulation of neuron differentiation;GO:0001649//osteoblast differentiation;GO:0001938//positive regulation of endothelial cell proliferation;GO:0045669//positive regulation of osteoblast differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0051384//response to glucocorticoid;GO:0010039//response to iron ion;GO:2000105//positive regulation of DNA-dependent DNA replication;GO:0032349//positive regulation of aldosterone biosynthetic process;GO:0060395//SMAD protein signal transduction;GO:0071260//cellular response to mechanical stimulus;GO:0045603//positive regulation of endothelial cell differentiation;GO:0032026//response to magnesium ion;GO:0001958//endochondral ossification;GO:0050714//positive regulation of protein secretion;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032526//response to retinoic acid,GO:0070700//BMP receptor binding;GO:0005125//cytokine activity;GO:0046982//protein heterodimerization activity;GO:0008083//growth factor activity,K04663//Cytokine-cytokine receptor interaction;Hedgehog signaling pathway;TGF-beta signaling pathway
6540,91,0,0,0,0,0,0,0,25,0,7,0,"SLC6A13;solute carrier family 6 (neurotransmitter transporter), member 13",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0015812//gamma-aminobutyric acid transport;GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion,GO:0005332//gamma-aminobutyric acid:sodium symporter activity;GO:0005328//neurotransmitter:sodium symporter activity,K05039//GABAergic synapse
6541,0,1,1,0,19,2,63,1,51,0,0,0,"SLC7A1;solute carrier family 7 (cationic amino acid transporter, y+ system), member 1",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0015809//arginine transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006810//transport;GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport,GO:0015181//arginine transmembrane transporter activity,-
6542,0,18,0,2,3,21,0,0,10,0,0,0,"SLC7A2;solute carrier family 7 (cationic amino acid transporter, y+ system), member 2",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006811//ion transport;GO:0006809//nitric oxide biosynthetic process;GO:0050727//regulation of inflammatory response;GO:0006810//transport;GO:0006520//cellular amino acid metabolic process;GO:0015809//arginine transport;GO:0055085//transmembrane transport;GO:0043030//regulation of macrophage activation;GO:0006865//amino acid transport;GO:0042116//macrophage activation;GO:0015819//lysine transport;GO:0002537//nitric oxide production involved in inflammatory response,GO:0005289//high-affinity arginine transmembrane transporter activity;GO:0015174//basic amino acid transmembrane transporter activity;GO:0000064//L-ornithine transmembrane transporter activity;GO:0015189//L-lysine transmembrane transporter activity,-
654231,0,0,0,0,0,0,0,0,9,0,0,0,OCM;oncomodulin,-,-,GO:0005509//calcium ion binding,-
654254,0,0,0,0,0,8,0,0,5,0,0,0,ZNF732;zinc finger protein 732,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
6543,0,0,0,0,2,0,0,0,40,0,0,0,"SLC8A2;solute carrier family 8 (sodium/calcium exchanger), member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007596//blood coagulation;GO:0007154//cell communication;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0006816//calcium ion transport;GO:0035725//sodium ion transmembrane transport,GO:0005516//calmodulin binding;GO:0005432//calcium:sodium antiporter activity,K05849//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;Calcium signaling pathway;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM)
654342,0,0,0,0,1,3,0,1,0,0,0,0,LOC654342;lymphocyte-specific protein 1 pseudogene,-,-,-,K14957//Tuberculosis
654346,0,0,0,0,0,0,25,0,20,0,0,9,"LGALS9C;lectin, galactoside-binding, soluble, 9C",-,-,GO:0030246//carbohydrate binding,-
654429,0,0,1,0,1,0,0,0,1,0,0,0,LRTM2;leucine-rich repeats and transmembrane domains 2,GO:0016021//integral component of membrane,-,-,K06839//Axon guidance
654434,0,0,0,0,0,15,0,0,0,0,0,0,SNHG20;small nucleolar RNA host gene 20 (non-protein coding),-,-,-,K11447//Transcriptional misregulation in cancer
654463,0,0,1,12,0,0,0,0,74,105,0,0,FER1L6;fer-1-like family member 6,GO:0016021//integral component of membrane,-,-,K02677//Non-small cell lung cancer;Vibrio cholerae infection;Melanogenesis;Fc epsilon RI signaling pathway;Cholinergic synapse;GABAergic synapse;Tight junction;Salivary secretion;B cell receptor signaling pathway;Vascular smooth muscle contraction;Wnt signaling pathway;Natural killer cell mediated cytotoxicity;Glutamatergic synapse;Amphetamine addiction;Amoebiasis;Phototransduction - fly;MAPK signaling pathway - yeast;Phosphatidylinositol signaling system;Carbohydrate digestion and absorption;Long-term potentiation;Pancreatic secretion;African trypanosomiasis;Aldosterone-regulated sodium reabsorption;Leishmaniasis;Focal adhesion;VEGF signaling pathway;Glioma;Pathogenic Escherichia coli infection;Gastric acid secretion;Long-term depression;Leukocyte transendothelial migration;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Calcium signaling pathway;Retrograde endocannabinoid signaling;Morphine addiction;MAPK signaling pathway;ErbB signaling pathway;NF-kappa B signaling pathway;Dopaminergic synapse;Gap junction;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Influenza A;Serotonergic synapse
654466,0,29,0,0,16,39,6,0,60,0,26,0,KGFLP2;keratinocyte growth factor-like protein 2,-,-,-,K04358//Melanoma;Regulation of actin cytoskeleton;MAPK signaling pathway;Pathways in cancer
6545,0,0,0,0,0,0,17,0,0,0,0,0,"SLC7A4;solute carrier family 7, member 4",GO:0016021//integral component of membrane,GO:0015802//basic amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0003333//amino acid transmembrane transport;GO:0006810//transport,GO:0015174//basic amino acid transmembrane transporter activity,-
654502,0,0,0,0,0,0,4,0,0,0,0,0,IQCJ;IQ motif containing J,-,-,-,-
6546,0,0,0,0,0,11,128,0,143,0,0,0,"SLC8A1;solute carrier family 8 (sodium/calcium exchanger), member 1",GO:0016323//basolateral plasma membrane;GO:0030315//T-tubule;GO:0014704//intercalated disc;GO:0042383//sarcolemma;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0030018//Z disc,GO:0009791//post-embryonic development;GO:0055013//cardiac muscle cell development;GO:0003007//heart morphogenesis;GO:0001892//embryonic placenta development;GO:0002026//regulation of the force of heart contraction;GO:0055074//calcium ion homeostasis;GO:1901660//calcium ion export;GO:0035050//embryonic heart tube development;GO:0006936//muscle contraction;GO:0002027//regulation of heart rate;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0060402//calcium ion transport into cytosol;GO:0044557//relaxation of smooth muscle;GO:0007596//blood coagulation;GO:0014829//vascular smooth muscle contraction;GO:0034614//cellular response to reactive oxygen species;GO:0048747//muscle fiber development;GO:0060048//cardiac muscle contraction;GO:0097369//sodium ion import;GO:0071436//sodium ion export;GO:0070509//calcium ion import;GO:0006883//cellular sodium ion homeostasis;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0055085//transmembrane transport;GO:0055119//relaxation of cardiac muscle;GO:0051481//negative regulation of cytosolic calcium ion concentration;GO:0071313//cellular response to caffeine;GO:0006811//ion transport;GO:0060401//cytosolic calcium ion transport,GO:0005432//calcium:sodium antiporter activity;GO:0046872//metal ion binding;GO:0030506//ankyrin binding;GO:0044325//ion channel binding;GO:0005516//calmodulin binding;GO:0008092//cytoskeletal protein binding,K05849//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Calcium signaling pathway;Dilated cardiomyopathy;Cardiac muscle contraction;Protein digestion and absorption;Hypertrophic cardiomyopathy (HCM)
6547,0,0,0,0,0,3,25,0,12,0,0,0,"SLC8A3;solute carrier family 8 (sodium/calcium exchanger), member 3",GO:0005886//plasma membrane;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0043197//dendritic spine;GO:0043025//neuronal cell body;GO:0005874//microtubule,GO:0006811//ion transport;GO:0071320//cellular response to cAMP;GO:0007596//blood coagulation;GO:0060402//calcium ion transport into cytosol;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:1990034//calcium ion export from cell;GO:0007154//cell communication;GO:0021537//telencephalon development;GO:1990035//calcium ion import into cell;GO:0002244//hematopoietic progenitor cell differentiation,GO:0005432//calcium:sodium antiporter activity;GO:0005516//calmodulin binding,K05849//Hypertrophic cardiomyopathy (HCM);Calcium signaling pathway;Dilated cardiomyopathy;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
654790,0,0,0,0,18,0,0,0,0,0,0,0,PCP4L1;Purkinje cell protein 4 like 1,-,-,-,-
6548,0,1,0,0,26,7,32,11,41,127,7,0,"SLC9A1;solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1",GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005739//mitochondrion;GO:0016323//basolateral plasma membrane;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,GO:0055007//cardiac muscle cell differentiation;GO:0071468//cellular response to acidic pH;GO:0051930//regulation of sensory perception of pain;GO:0045760//positive regulation of action potential;GO:0035794//positive regulation of mitochondrial membrane permeability;GO:1902600//hydrogen ion transmembrane transport;GO:0014070//response to organic cyclic compound;GO:0005975//carbohydrate metabolic process;GO:0030212//hyaluronan metabolic process;GO:0030214//hyaluronan catabolic process;GO:0070997//neuron death;GO:0030203//glycosaminoglycan metabolic process;GO:0002026//regulation of the force of heart contraction;GO:0030307//positive regulation of cell growth;GO:0001101//response to acid chemical;GO:0006811//ion transport;GO:0051453//regulation of intracellular pH;GO:0055085//transmembrane transport;GO:0043066//negative regulation of apoptotic process;GO:0051259//protein oligomerization;GO:0042493//response to drug;GO:0016049//cell growth;GO:0071436//sodium ion export;GO:0010447//response to acidic pH;GO:0006885//regulation of pH;GO:0044281//small molecule metabolic process,GO:0048306//calcium-dependent protein binding;GO:0015385//sodium:proton antiporter activity;GO:0005515//protein binding;GO:0005516//calmodulin binding;GO:0015299//solute:proton antiporter activity,K05742//Gastric acid secretion;Pancreatic secretion;Bile secretion;Cardiac muscle contraction;Salivary secretion;Regulation of actin cytoskeleton
654816,0,0,15,0,0,0,0,0,9,2,0,0,NCF1B;neutrophil cytosolic factor 1B pseudogene,GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process,GO:0035091//phosphatidylinositol binding;GO:0016175//superoxide-generating NADPH oxidase activity,K08011//Phagosome;Chemokine signaling pathway;Leishmaniasis;Osteoclast differentiation;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis
654817,4,0,0,0,0,5,0,13,1,13,0,0,NCF1C;neutrophil cytosolic factor 1C pseudogene,GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process,GO:0016175//superoxide-generating NADPH oxidase activity;GO:0035091//phosphatidylinositol binding,K08011//Leishmaniasis;Osteoclast differentiation;Chemokine signaling pathway;Phagosome;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration
6549,0,0,0,0,16,0,11,8,27,0,0,0,"SLC9A2;solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0006811//ion transport;GO:0006885//regulation of pH;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0008104//protein localization,GO:0015385//sodium:proton antiporter activity,-
655,73,0,0,0,0,26,0,66,7,0,2,0,BMP7;bone morphogenetic protein 7,GO:0031012//extracellular matrix;GO:0031988//membrane-bounded vesicle;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0072125//negative regulation of glomerular mesangial cell proliferation;GO:2000121//regulation of removal of superoxide radicals;GO:0045839//negative regulation of mitosis;GO:0030509//BMP signaling pathway;GO:0045786//negative regulation of cell cycle;GO:0032355//response to estradiol;GO:0016358//dendrite development;GO:0043401//steroid hormone mediated signaling pathway;GO:0060687//regulation of branching involved in prostate gland morphogenesis;GO:0060548//negative regulation of cell death;GO:0001503//ossification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060395//SMAD protein signal transduction;GO:0001656//metanephros development;GO:0060445//branching involved in salivary gland morphogenesis;GO:0007411//axon guidance;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0001657//ureteric bud development;GO:0042326//negative regulation of phosphorylation;GO:0060686//negative regulation of prostatic bud formation;GO:1900006//positive regulation of dendrite development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043434//response to peptide hormone;GO:0030326//embryonic limb morphogenesis;GO:0051216//cartilage development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:1900106//positive regulation of hyaluranon cable assembly;GO:0001823//mesonephros development;GO:0060272//embryonic skeletal joint morphogenesis;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060393//regulation of pathway-restricted SMAD protein phosphorylation;GO:0070487//monocyte aggregation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045666//positive regulation of neuron differentiation;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0030501//positive regulation of bone mineralization;GO:0048596//embryonic camera-type eye morphogenesis;GO:0001501//skeletal system development;GO:0030855//epithelial cell differentiation;GO:0040007//growth;GO:0001707//mesoderm formation;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0030198//extracellular matrix organization;GO:0072134//nephrogenic mesenchyme morphogenesis;GO:0072133//metanephric mesenchyme morphogenesis;GO:0071456//cellular response to hypoxia;GO:0048762//mesenchymal cell differentiation;GO:0048812//neuron projection morphogenesis;GO:0045669//positive regulation of osteoblast differentiation;GO:0072040//negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0045665//negative regulation of neuron differentiation;GO:0009880//embryonic pattern specification;GO:0033280//response to vitamin D;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0060485//mesenchyme development;GO:0034504//protein localization to nucleus;GO:0050768//negative regulation of neurogenesis;GO:0043407//negative regulation of MAP kinase activity;GO:0043065//positive regulation of apoptotic process;GO:0045746//negative regulation of Notch signaling pathway",GO:0008201//heparin binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity,K04663//TGF-beta signaling pathway;Hedgehog signaling pathway;Cytokine-cytokine receptor interaction
6550,0,0,0,16,34,22,1,368,6,0,81,1,"SLC9A3;solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3",GO:0005903//brush border;GO:0016324//apical plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0006885//regulation of pH;GO:0035725//sodium ion transmembrane transport,GO:0005515//protein binding;GO:0015385//sodium:proton antiporter activity;GO:0030165//PDZ domain binding,K12040//Mineral absorption;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Bile secretion
6553,217,0,0,10,0,0,70,26,62,0,49,305,"SLC9A5;solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0006810//transport;GO:0006811//ion transport;GO:0006885//regulation of pH;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport,GO:0015385//sodium:proton antiporter activity,-
6554,0,0,0,0,0,0,42,141,25,0,0,0,"SLC10A1;solute carrier family 10 (sodium/bile acid cotransporter), member 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane,GO:0008206//bile acid metabolic process;GO:0055085//transmembrane transport;GO:0015721//bile acid and bile salt transport;GO:0044281//small molecule metabolic process;GO:0006810//transport;GO:0006814//sodium ion transport,GO:0008508//bile acid:sodium symporter activity,K14341//Bile secretion
6555,0,0,0,0,0,19,0,0,14,0,0,0,"SLC10A2;solute carrier family 10 (sodium/bile acid cotransporter), member 2",GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0000502//proteasome complex,GO:0044281//small molecule metabolic process;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport;GO:0008206//bile acid metabolic process;GO:0006814//sodium ion transport;GO:0006810//transport,GO:0008508//bile acid:sodium symporter activity,K14342//Bile secretion
6556,65,0,0,4,18,0,0,165,23,0,17,0,"SLC11A1;solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1",GO:0070821//tertiary granule membrane;GO:0009279//cell outer membrane;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0005770//late endosome;GO:0031902//late endosome membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome,"GO:0050829//defense response to Gram-negative bacterium;GO:0042742//defense response to bacterium;GO:0010628//positive regulation of gene expression;GO:0032147//activation of protein kinase activity;GO:0006826//iron ion transport;GO:0051701//interaction with host;GO:0006876//cellular cadmium ion homeostasis;GO:0001818//negative regulation of cytokine production;GO:0048255//mRNA stabilization;GO:0009617//response to bacterium;GO:0006909//phagocytosis;GO:0050766//positive regulation of phagocytosis;GO:0032632//interleukin-3 production;GO:0007035//vacuolar acidification;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0045342//MHC class II biosynthetic process;GO:0034341//response to interferon-gamma;GO:0032729//positive regulation of interferon-gamma production;GO:0042116//macrophage activation;GO:0002369//T cell cytokine production;GO:0042832//defense response to protozoan;GO:0006879//cellular iron ion homeostasis;GO:0002309//T cell proliferation involved in immune response;GO:0042060//wound healing;GO:0032496//response to lipopolysaccharide;GO:0001819//positive regulation of cytokine production;GO:0055072//iron ion homeostasis;GO:0006828//manganese ion transport;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:0055085//transmembrane transport;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0015707//nitrite transport;GO:0000060//protein import into nucleus, translocation;GO:0070839//divalent metal ion export;GO:0090382//phagosome maturation;GO:0060586//multicellular organismal iron ion homeostasis;GO:0045730//respiratory burst;GO:0032623//interleukin-2 production;GO:0070574//cadmium ion transmembrane transport;GO:0071421//manganese ion transmembrane transport;GO:0048002//antigen processing and presentation of peptide antigen;GO:0043091//L-arginine import",GO:0051139//metal ion:proton antiporter activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0042803//protein homodimerization activity,K12347//Lysosome;Mineral absorption
6557,0,0,0,0,0,0,0,0,31,0,11,0,"SLC12A1;solute carrier family 12 (sodium/potassium/chloride transporter), member 1",GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport;GO:0006814//sodium ion transport;GO:0008219//cell death;GO:0006821//chloride transport;GO:0001822//kidney development;GO:0006813//potassium ion transport;GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007588//excretion;GO:0048878//chemical homeostasis;GO:0055085//transmembrane transport,GO:0008511//sodium:potassium:chloride symporter activity,-
6558,0,38,0,14,85,16,0,46,81,2,0,0,"SLC12A2;solute carrier family 12 (sodium/potassium/chloride transporter), member 2",GO:0031982//vesicle;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016020//membrane,GO:0030321//transepithelial chloride transport;GO:1902476//chloride transmembrane transport;GO:0045795//positive regulation of cell volume;GO:0006814//sodium ion transport;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0060763//mammary duct terminal end bud growth;GO:0006810//transport;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0070634//transepithelial ammonium transport;GO:0055085//transmembrane transport;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0006972//hyperosmotic response;GO:0035264//multicellular organism growth;GO:0006813//potassium ion transport;GO:0072488//ammonium transmembrane transport;GO:0006811//ion transport,GO:0005515//protein binding;GO:0008519//ammonium transmembrane transporter activity;GO:0008511//sodium:potassium:chloride symporter activity,K10951//Salivary secretion;Vibrio cholerae infection;Pancreatic secretion
6559,0,0,0,0,0,44,17,32,78,0,5,1,"SLC12A3;solute carrier family 12 (sodium/chloride transporter), member 3",GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0006810//transport;GO:0006811//ion transport;GO:0006814//sodium ion transport;GO:1902476//chloride transmembrane transport;GO:0055085//transmembrane transport;GO:0006821//chloride transport;GO:0035725//sodium ion transmembrane transport,GO:0005215//transporter activity;GO:0005515//protein binding,-
656,2,0,0,49,176,0,0,1,2,82,156,0,BMP8B;bone morphogenetic protein 8b,GO:0005615//extracellular space,GO:0001503//ossification;GO:0030154//cell differentiation;GO:0001501//skeletal system development;GO:0040007//growth;GO:0051216//cartilage development,GO:0005125//cytokine activity;GO:0008083//growth factor activity,K04663//Hedgehog signaling pathway;Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
6560,0,0,0,0,0,0,70,0,101,0,0,217,"SLC12A4;solute carrier family 12 (potassium/chloride transporter), member 4",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane,GO:0006884//cell volume homeostasis;GO:0006821//chloride transport;GO:0055085//transmembrane transport;GO:0006813//potassium ion transport;GO:1902476//chloride transmembrane transport;GO:0006811//ion transport;GO:0006810//transport,GO:0015379//potassium:chloride symporter activity;GO:0019901//protein kinase binding,K14427//GABAergic synapse
6561,0,0,0,0,0,25,29,0,61,0,2,0,"SLC13A1;solute carrier family 13 (sodium/sulfate symporter), member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:1902358//sulfate transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport,GO:0015382//sodium:sulfate symporter activity,-
6563,0,0,0,0,0,33,0,0,27,0,7,0,"SLC14A1;solute carrier family 14 (urea transporter), member 1 (Kidd blood group)",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane,GO:0055085//transmembrane transport;GO:0006833//water transport;GO:0071918//urea transmembrane transport;GO:0015840//urea transport,GO:0015204//urea transmembrane transporter activity;GO:0005372//water transmembrane transporter activity;GO:0015265//urea channel activity,-
6564,0,0,0,0,0,34,2,0,25,0,0,0,"SLC15A1;solute carrier family 15 (oligopeptide transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0006810//transport;GO:0007586//digestion;GO:0035672//oligopeptide transmembrane transport;GO:0006811//ion transport;GO:0015992//proton transport;GO:0055085//transmembrane transport;GO:0015031//protein transport,GO:0005427//proton-dependent oligopeptide secondary active transmembrane transporter activity;GO:0015333//peptide:proton symporter activity,K14206//Protein digestion and absorption
6565,56,41,0,41,22,14,13,0,6,0,0,0,"SLC15A2;solute carrier family 15 (oligopeptide transporter), member 2",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0042938//dipeptide transport;GO:0015031//protein transport;GO:0006810//transport;GO:0006811//ion transport;GO:0015992//proton transport;GO:0015893//drug transport;GO:0042891//antibiotic transport,GO:0015334//high-affinity oligopeptide transporter activity;GO:0015333//peptide:proton symporter activity;GO:0042895//antibiotic transporter activity;GO:0042936//dipeptide transporter activity;GO:0005515//protein binding,-
6566,0,0,0,7,66,0,65,0,5,122,0,0,"SLC16A1;solute carrier family 16 (monocarboxylate transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0005813//centrosome;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0071407//cellular response to organic cyclic compound;GO:0055085//transmembrane transport;GO:0051297//centrosome organization;GO:0015718//monocarboxylic acid transport;GO:0050796//regulation of insulin secretion;GO:0032094//response to food;GO:0007596//blood coagulation;GO:0044281//small molecule metabolic process;GO:0050900//leukocyte migration;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0015728//mevalonate transport;GO:0006629//lipid metabolic process;GO:0042593//glucose homeostasis;GO:0035879//plasma membrane lactate transport,GO:0015293//symporter activity;GO:0015130//mevalonate transmembrane transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015355//secondary active monocarboxylate transmembrane transporter activity;GO:0097159//organic cyclic compound binding;GO:0042803//protein homodimerization activity,-
6567,51,0,0,6,0,5,0,32,37,13,0,0,"SLC16A2;solute carrier family 16, member 2 (thyroid hormone transporter)",GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0006810//transport;GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity,-
6568,0,0,0,0,0,14,16,0,2,0,0,0,"SLC17A1;solute carrier family 17 (organic anion transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0006814//sodium ion transport;GO:0006811//ion transport;GO:0046415//urate metabolic process;GO:0006817//phosphate ion transport;GO:0044341//sodium-dependent phosphate transport;GO:0055085//transmembrane transport;GO:0035435//phosphate ion transmembrane transport,GO:0015293//symporter activity;GO:0015321//sodium-dependent phosphate transmembrane transporter activity,-
6569,0,0,0,0,0,0,0,48,78,182,7,37,"SLC34A1;solute carrier family 34 (type II sodium/phosphate contransporter), member 1",GO:0016324//apical plasma membrane;GO:0005886//plasma membrane;GO:0005768//endosome;GO:0031526//brush border membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane;GO:0031988//membrane-bounded vesicle;GO:0016323//basolateral plasma membrane,GO:0001822//kidney development;GO:1901128//gentamycin metabolic process;GO:0044341//sodium-dependent phosphate transport;GO:1901684//arsenate ion transmembrane transport;GO:0042431//indole metabolic process;GO:2000187//positive regulation of phosphate transmembrane transport;GO:0097187//dentinogenesis;GO:0010288//response to lead ion;GO:0035864//response to potassium ion;GO:0072734//cellular response to staurosporine;GO:0006811//ion transport;GO:0033189//response to vitamin A;GO:0097066//response to thyroid hormone;GO:0032355//response to estradiol;GO:0072350//tricarboxylic acid metabolic process;GO:0055062//phosphate ion homeostasis;GO:0006814//sodium ion transport;GO:0046849//bone remodeling;GO:0006817//phosphate ion transport;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0042493//response to drug;GO:0001503//ossification;GO:0051260//protein homooligomerization;GO:0055085//transmembrane transport;GO:0060416//response to growth hormone;GO:0009100//glycoprotein metabolic process;GO:0046689//response to mercury ion;GO:0046686//response to cadmium ion;GO:0032026//response to magnesium ion;GO:2000120//positive regulation of sodium-dependent phosphate transport;GO:0045838//positive regulation of membrane potential;GO:0071248//cellular response to metal ion,GO:0015321//sodium-dependent phosphate transmembrane transporter activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0032403//protein complex binding;GO:0030165//PDZ domain binding;GO:0015293//symporter activity,K14683//Mineral absorption
657,0,13,15,23,38,9,24,135,128,0,63,0,"BMPR1A;bone morphogenetic protein receptor, type IA",GO:0043025//neuronal cell body;GO:0005901//caveola;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0005886//plasma membrane,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0003272//endocardial cushion formation;GO:0045669//positive regulation of osteoblast differentiation;GO:0021983//pituitary gland development;GO:0001756//somitogenesis;GO:0007398//ectoderm development;GO:0021998//neural plate mediolateral regionalization;GO:0042733//embryonic digit morphogenesis;GO:0048378//regulation of lateral mesodermal cell fate specification;GO:0001880//Mullerian duct regression;GO:0048352//paraxial mesoderm structural organization;GO:0048368//lateral mesoderm development;GO:0050768//negative regulation of neurogenesis;GO:0030324//lung development;GO:0014032//neural crest cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0009950//dorsal/ventral axis specification;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0060914//heart formation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0051216//cartilage development;GO:0048568//embryonic organ development;GO:0006955//immune response;GO:0060021//palate development;GO:0048382//mesendoderm development;GO:0030509//BMP signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0030501//positive regulation of bone mineralization;GO:0023014//signal transduction by phosphorylation;GO:0048589//developmental growth;GO:0035137//hindlimb morphogenesis;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0019827//stem cell maintenance",GO:0005024//transforming growth factor beta-activated receptor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0046332//SMAD binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,K04673//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
6570,0,0,0,0,0,3,10,0,18,0,0,195,"SLC18A1;solute carrier family 18 (vesicular monoamine transporter), member 1",GO:0016021//integral component of membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane,GO:0055085//transmembrane transport;GO:0015844//monoamine transport;GO:0006836//neurotransmitter transport;GO:0006855//drug transmembrane transport,GO:0015238//drug transmembrane transporter activity;GO:0008504//monoamine transmembrane transporter activity,K08155//Serotonergic synapse;Alcoholism;Synaptic vesicle cycle;Parkinson's disease;Dopaminergic synapse;Cocaine addiction;Amphetamine addiction
6571,0,37,25,22,25,16,13,0,10,0,35,0,"SLC18A2;solute carrier family 18 (vesicular monoamine transporter), member 2",GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0043195//terminal bouton;GO:0031045//dense core granule;GO:0030672//synaptic vesicle membrane;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0043025//neuronal cell body,GO:0009635//response to herbicide;GO:0051412//response to corticosterone;GO:0006837//serotonin transport;GO:0007268//synaptic transmission;GO:0032456//endocytic recycling;GO:0007568//aging;GO:0030073//insulin secretion;GO:0001975//response to amphetamine;GO:0010043//response to zinc ion;GO:0009791//post-embryonic development;GO:0035690//cellular response to drug;GO:0015837//amine transport;GO:0042594//response to starvation;GO:0055085//transmembrane transport;GO:0007269//neurotransmitter secretion;GO:0007626//locomotory behavior;GO:0071242//cellular response to ammonium ion;GO:0015872//dopamine transport;GO:0042593//glucose homeostasis;GO:0016265//death;GO:0015844//monoamine transport;GO:0051589//negative regulation of neurotransmitter transport;GO:0042220//response to cocaine,GO:0008144//drug binding;GO:0019899//enzyme binding;GO:0031072//heat shock protein binding;GO:0015222//serotonin transmembrane transporter activity;GO:0005275//amine transmembrane transporter activity;GO:0008504//monoamine transmembrane transporter activity,K08155//Parkinson's disease;Amphetamine addiction;Dopaminergic synapse;Cocaine addiction;Alcoholism;Serotonergic synapse;Synaptic vesicle cycle
6572,41,0,0,0,0,0,0,0,10,0,0,0,"SLC18A3;solute carrier family 18 (vesicular acetylcholine transporter), member 3",GO:0005886//plasma membrane;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0015870//acetylcholine transport;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion,GO:0005277//acetylcholine transmembrane transporter activity,K14636//Cholinergic synapse;Synaptic vesicle cycle
6573,0,0,0,0,0,10,0,0,23,143,6,1,"SLC19A1;solute carrier family 19 (folate transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0046655//folic acid metabolic process;GO:0015884//folic acid transport;GO:0051958//methotrexate transport;GO:0006766//vitamin metabolic process,GO:0015350//methotrexate transporter activity;GO:0005542//folic acid binding;GO:0008517//folic acid transporter activity,K14609//Vitamin digestion and absorption
6574,0,0,20,11,0,0,0,0,11,0,0,0,"SLC20A1;solute carrier family 20 (phosphate transporter), member 1",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0006810//transport;GO:0006811//ion transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035435//phosphate ion transmembrane transport;GO:0006796//phosphate-containing compound metabolic process;GO:0007165//signal transduction,GO:0005436//sodium:phosphate symporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0004871//signal transducer activity;GO:0005316//high-affinity inorganic phosphate:sodium symporter activity;GO:0004872//receptor activity,-
6575,0,50,0,47,44,0,20,109,3,0,74,0,"SLC20A2;solute carrier family 20 (phosphate transporter), member 2",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0016032//viral process;GO:0006810//transport;GO:0006811//ion transport;GO:0035435//phosphate ion transmembrane transport;GO:0055085//transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0009615//response to virus,GO:0005436//sodium:phosphate symporter activity;GO:0005315//inorganic phosphate transmembrane transporter activity;GO:0004872//receptor activity;GO:0001618//virus receptor activity,-
6576,0,1,0,10,30,9,0,0,11,0,12,0,"SLC25A1;solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005634//nucleus,GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0055085//transmembrane transport;GO:0015746//citrate transport;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0006094//gluconeogenesis,GO:0015137//citrate transmembrane transporter activity,-
6578,0,0,0,0,0,12,0,0,15,0,0,0,"SLCO2A1;solute carrier organic anion transporter family, member 2A1",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0015732//prostaglandin transport;GO:0006869//lipid transport;GO:0043252//sodium-independent organic anion transport,GO:0005319//lipid transporter activity;GO:0015132//prostaglandin transmembrane transporter activity,-
6579,168,0,0,0,0,21,20,72,23,0,0,0,"SLCO1A2;solute carrier organic anion transporter family, member 1A2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0043252//sodium-independent organic anion transport;GO:0044281//small molecule metabolic process;GO:0015711//organic anion transport;GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport;GO:0008206//bile acid metabolic process,GO:0008514//organic anion transmembrane transporter activity,K03460//Bile secretion
658,0,83,0,38,74,0,0,0,38,0,0,0,"BMPR1B;bone morphogenetic protein receptor, type IB",GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex;GO:0005886//plasma membrane,GO:0023014//signal transduction by phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0006954//inflammatory response;GO:0060041//retina development in camera-type eye;GO:0042698//ovulation cycle;GO:0006468//protein phosphorylation;GO:0001502//cartilage condensation;GO:0035108//limb morphogenesis;GO:0001501//skeletal system development;GO:0045597//positive regulation of cell differentiation;GO:0045669//positive regulation of osteoblast differentiation;GO:0031290//retinal ganglion cell axon guidance;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0001550//ovarian cumulus expansion;GO:0030509//BMP signaling pathway;GO:0002062//chondrocyte differentiation;GO:0009953//dorsal/ventral pattern formation;GO:0001654//eye development,"GO:0005025//transforming growth factor beta receptor activity, type I;GO:0005524//ATP binding;GO:0046332//SMAD binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding",K13578//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
6580,45,0,0,0,7,3,22,0,11,0,13,0,"SLC22A1;solute carrier family 22 (organic cation transporter), member 1",GO:0016020//membrane;GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006855//drug transmembrane transport;GO:1901374//acetate ester transport;GO:0015874//norepinephrine transport;GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0010248//establishment or maintenance of transmembrane electrochemical gradient;GO:0048241//epinephrine transport;GO:0015872//dopamine transport;GO:0015695//organic cation transport;GO:0051260//protein homooligomerization;GO:0044281//small molecule metabolic process;GO:0006836//neurotransmitter transport,GO:0005329//dopamine transmembrane transporter activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005333//norepinephrine transmembrane transporter activity;GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity;GO:0005277//acetylcholine transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity,K08198//Bile secretion
6581,0,68,0,13,7,10,0,27,12,0,19,0,"SLC22A3;solute carrier family 22 (organic cation transporter), member 3",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0006855//drug transmembrane transport;GO:1901998//toxin transport;GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0032098//regulation of appetite;GO:0015695//organic cation transport;GO:0015872//dopamine transport;GO:0051615//histamine uptake;GO:0044281//small molecule metabolic process,GO:0015101//organic cation transmembrane transporter activity;GO:0005329//dopamine transmembrane transporter activity;GO:0019534//toxin transporter activity;GO:0005515//protein binding;GO:0015651//quaternary ammonium group transmembrane transporter activity,-
6582,2,0,0,0,0,0,0,0,15,0,1,301,"SLC22A2;solute carrier family 22 (organic cation transporter), member 2",GO:0016323//basolateral plasma membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0007268//synaptic transmission;GO:0051608//histamine transport;GO:0007269//neurotransmitter secretion;GO:0006855//drug transmembrane transport;GO:0034220//ion transmembrane transport;GO:0015871//choline transport;GO:0042136//neurotransmitter biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007589//body fluid secretion;GO:0015695//organic cation transport,GO:0005496//steroid binding;GO:0015101//organic cation transmembrane transporter activity;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0015220//choline transmembrane transporter activity,-
6583,27,0,0,12,13,34,2,0,25,0,0,0,"SLC22A4;solute carrier family 22 (organic cation/zwitterion transporter), member 4",GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0005739//mitochondrion;GO:0005886//plasma membrane,GO:0007589//body fluid secretion;GO:0006814//sodium ion transport;GO:0015695//organic cation transport;GO:1902603//carnitine transmembrane transport;GO:0009437//carnitine metabolic process;GO:0015879//carnitine transport;GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0006641//triglyceride metabolic process,GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008513//secondary active organic cation transmembrane transporter activity;GO:0015293//symporter activity;GO:0015226//carnitine transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0015491//cation:cation antiporter activity;GO:0005524//ATP binding,-
6584,0,0,0,0,0,0,0,19,44,23,0,0,"SLC22A5;solute carrier family 22 (organic cation/carnitine transporter), member 5",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016324//apical plasma membrane,GO:1902603//carnitine transmembrane transport;GO:0060731//positive regulation of intestinal epithelial structure maintenance;GO:0015879//carnitine transport;GO:0015893//drug transport;GO:0042891//antibiotic transport;GO:0070715//sodium-dependent organic cation transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0052106//quorum sensing involved in interaction with host;GO:0006855//drug transmembrane transport,GO:0005515//protein binding;GO:0015238//drug transmembrane transporter activity;GO:0015293//symporter activity;GO:0015226//carnitine transmembrane transporter activity;GO:0030165//PDZ domain binding;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0042895//antibiotic transporter activity;GO:0005524//ATP binding,-
6585,221,0,0,5,8,35,51,86,121,0,23,0,SLIT1;slit homolog 1 (Drosophila),GO:0005615//extracellular space,GO:0048846//axon extension involved in axon guidance;GO:0007411//axon guidance;GO:0050919//negative chemotaxis;GO:0008045//motor neuron axon guidance;GO:0048853//forebrain morphogenesis;GO:0033563//dorsal/ventral axon guidance;GO:0031290//retinal ganglion cell axon guidance;GO:0040023//establishment of nucleus localization;GO:0021510//spinal cord development;GO:0021834//chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration;GO:0051964//negative regulation of synapse assembly;GO:0048843//negative regulation of axon extension involved in axon guidance,GO:0043395//heparan sulfate proteoglycan binding;GO:0005509//calcium ion binding;GO:0048495//Roundabout binding,K06838//Axon guidance
6586,1,0,0,0,0,30,17,90,160,0,38,3,SLIT3;slit homolog 3 (Drosophila),GO:0005615//extracellular space;GO:0005739//mitochondrion,GO:0050919//negative chemotaxis;GO:0035385//Roundabout signaling pathway;GO:0030308//negative regulation of cell growth;GO:0061364//apoptotic process involved in luteolysis;GO:0009887//organ morphogenesis;GO:0048846//axon extension involved in axon guidance;GO:0007411//axon guidance;GO:0008285//negative regulation of cell proliferation;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0032870//cellular response to hormone stimulus;GO:0051414//response to cortisol;GO:0021834//chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration;GO:0010629//negative regulation of gene expression,GO:0005509//calcium ion binding;GO:0048495//Roundabout binding,K06850//Axon guidance
659,0,32,0,6,96,11,66,46,29,0,0,0,"BMPR2;bone morphogenetic protein receptor, type II (serine/threonine kinase)",GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0009986//cell surface;GO:0044214//fully spanning plasma membrane;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007420//brain development;GO:0030308//negative regulation of cell growth;GO:0014916//regulation of lung blood pressure;GO:0030509//BMP signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0009267//cellular response to starvation;GO:0023014//signal transduction by phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0042127//regulation of cell proliferation;GO:0001946//lymphangiogenesis;GO:0009952//anterior/posterior pattern specification;GO:0030513//positive regulation of BMP signaling pathway;GO:0060840//artery development;GO:0060836//lymphatic endothelial cell differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0002063//chondrocyte development;GO:0061298//retina vasculature development in camera-type eye;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:2000279//negative regulation of DNA biosynthetic process;GO:0045906//negative regulation of vasoconstriction;GO:0032924//activin receptor signaling pathway;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0001974//blood vessel remodeling;GO:0045669//positive regulation of osteoblast differentiation;GO:0048286//lung alveolus development;GO:0001707//mesoderm formation;GO:0060173//limb development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0060841//venous blood vessel development;GO:1902731//negative regulation of chondrocyte proliferation;GO:0006468//protein phosphorylation;GO:0010634//positive regulation of epithelial cell migration;GO:0006366//transcription from RNA polymerase II promoter,"GO:0019838//growth factor binding;GO:0016362//activin receptor activity, type II;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0005515//protein binding",K04671//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
6590,0,0,0,0,0,8,0,0,12,108,0,0,SLPI;secretory leukocyte peptidase inhibitor,GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome,GO:0032091//negative regulation of protein binding;GO:0045071//negative regulation of viral genome replication;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0019899//enzyme binding;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding,-
6591,0,0,0,0,0,0,0,10,5,0,0,0,SNAI2;snail family zinc finger 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0071364//cellular response to epidermal growth factor stimulus;GO:0060070//canonical Wnt signaling pathway;GO:0033629//negative regulation of cell adhesion mediated by integrin;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0030335//positive regulation of cell migration;GO:0007605//sensory perception of sound;GO:0032331//negative regulation of chondrocyte differentiation;GO:0043473//pigmentation;GO:0001837//epithelial to mesenchymal transition;GO:0006366//transcription from RNA polymerase II promoter;GO:0014032//neural crest cell development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045667//regulation of osteoblast differentiation;GO:0003273//cell migration involved in endocardial cushion formation;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0007219//Notch signaling pathway;GO:0050872//white fat cell differentiation;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0035066//positive regulation of histone acetylation;GO:2000811//negative regulation of anoikis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000810//regulation of tight junction assembly;GO:0070563//negative regulation of vitamin D receptor signaling pathway;GO:0035414//negative regulation of catenin import into nucleus;GO:0003198//epithelial to mesenchymal transition involved in endocardial cushion formation;GO:0032642//regulation of chemokine production;GO:1900387//negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter;GO:0060021//palate development;GO:0009790//embryo development;GO:0071479//cellular response to ionizing radiation;GO:0060693//regulation of branching involved in salivary gland morphogenesis;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0010839//negative regulation of keratinocyte proliferation;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0060429//epithelium development;GO:0035921//desmosome disassembly;GO:0060536//cartilage morphogenesis;GO:0001649//osteoblast differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:2000647//negative regulation of stem cell proliferation",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding,K05706//Adherens junction
6594,17,36,0,86,124,0,36,0,19,0,0,0,"SMARCA1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1",GO:0090537//CERF complex;GO:0016589//NURF complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0030182//neuron differentiation;GO:0007420//brain development;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000177//regulation of neural precursor cell proliferation;GO:0000733//DNA strand renaturation;GO:0006200//ATP catabolic process;GO:0043044//ATP-dependent chromatin remodeling",GO:0005524//ATP binding;GO:0031491//nucleosome binding;GO:0070615//nucleosome-dependent ATPase activity;GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0008094//DNA-dependent ATPase activity;GO:0036310//annealing helicase activity;GO:0005515//protein binding,-
6595,0,22,0,59,167,12,60,72,49,431,2,0,"SMARCA2;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2",GO:0071564//npBAF complex;GO:0005654//nucleoplasm;GO:0016514//SWI/SNF complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0071565//nBAF complex;GO:0043231//intracellular membrane-bounded organelle;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus,"GO:0007399//nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030308//negative regulation of cell growth;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0035887//aortic smooth muscle cell differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006200//ATP catabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0001105//RNA polymerase II transcription coactivator activity;GO:0004386//helicase activity;GO:0003713//transcription coactivator activity;GO:0005524//ATP binding;GO:0042393//histone binding;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0008094//DNA-dependent ATPase activity,-
6596,0,28,0,42,215,11,0,0,31,0,9,0,HLTF;helicase-like transcription factor,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0006200//ATP catabolic process;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0016874//ligase activity,-
6597,1,27,0,7,62,0,16,0,36,0,8,0,"SMARCA4;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4",GO:0071564//npBAF complex;GO:0043234//protein complex;GO:0016514//SWI/SNF complex;GO:0016020//membrane;GO:0000792//heterochromatin;GO:0005726//perichromatin fibrils;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0071565//nBAF complex;GO:0005719//nuclear euchromatin;GO:0005615//extracellular space;GO:0005730//nucleolus,"GO:0030216//keratinocyte differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035887//aortic smooth muscle cell differentiation;GO:0000902//cell morphogenesis;GO:0043966//histone H3 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007403//glial cell fate determination;GO:0060318//definitive erythrocyte differentiation;GO:0030900//forebrain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006346//methylation-dependent chromatin silencing;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0007070//negative regulation of transcription from RNA polymerase II promoter during mitosis;GO:0060347//heart trabecula formation;GO:0001570//vasculogenesis;GO:0043044//ATP-dependent chromatin remodeling;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0003407//neural retina development;GO:0048730//epidermis morphogenesis;GO:0019827//stem cell maintenance;GO:0070307//lens fiber cell development;GO:0043923//positive regulation by host of viral transcription;GO:0001832//blastocyst growth;GO:0006338//chromatin remodeling;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010424//DNA methylation on cytosine within a CG sequence;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0001835//blastocyst hatching;GO:0030902//hindbrain development;GO:0030308//negative regulation of cell growth;GO:0043388//positive regulation of DNA binding;GO:0006351//transcription, DNA-templated;GO:0001889//liver development;GO:0035116//embryonic hindlimb morphogenesis;GO:0006337//nucleosome disassembly;GO:0048562//embryonic organ morphogenesis",GO:0003714//transcription corepressor activity;GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0070577//lysine-acetylated histone binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0047485//protein N-terminus binding;GO:0004386//helicase activity;GO:0002039//p53 binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0030957//Tat protein binding;GO:0050681//androgen receptor binding;GO:0008094//DNA-dependent ATPase activity;GO:0005515//protein binding,-
65975,0,0,0,0,0,0,38,0,18,0,0,0,STK33;serine/threonine kinase 33,GO:0048471//perinuclear region of cytoplasm,GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
65977,0,0,0,15,65,0,3,0,8,0,0,0,"PLEKHA3;pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3",GO:0005794//Golgi apparatus;GO:0016020//membrane,-,GO:0005545//1-phosphatidylinositol binding;GO:0005543//phospholipid binding,-
65979,173,41,1,44,191,42,2,64,78,43,0,0,PHACTR4;phosphatase and actin regulator 4,GO:0030027//lamellipodium;GO:0005737//cytoplasm,GO:0001843//neural tube closure;GO:0007266//Rho protein signal transduction;GO:0061386//closure of optic fissure;GO:0030036//actin cytoskeleton organization;GO:0048484//enteric nervous system development;GO:0043085//positive regulation of catalytic activity;GO:2001045//negative regulation of integrin-mediated signaling pathway;GO:0051726//regulation of cell cycle;GO:0001755//neural crest cell migration,GO:0008157//protein phosphatase 1 binding;GO:0003779//actin binding;GO:0071862//protein phosphatase type 1 activator activity,K11447//Transcriptional misregulation in cancer
6598,0,1,0,6,25,20,0,0,2,0,0,0,"SMARCB1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1",GO:0071564//npBAF complex;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016514//SWI/SNF complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0001741//XY body;GO:0071565//nBAF complex;GO:0005730//nucleolus,"GO:0006281//DNA repair;GO:0001835//blastocyst hatching;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043923//positive regulation by host of viral transcription;GO:0007399//nervous system development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006338//chromatin remodeling;GO:0039692//single stranded viral RNA replication via double stranded DNA intermediate;GO:0043044//ATP-dependent chromatin remodeling;GO:0006337//nucleosome disassembly;GO:0015074//DNA integration;GO:0008285//negative regulation of cell proliferation;GO:0044772//mitotic cell cycle phase transition;GO:0006351//transcription, DNA-templated",GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0030957//Tat protein binding;GO:0005515//protein binding;GO:0002039//p53 binding,-
65980,61,0,26,0,0,0,35,160,44,0,0,0,BRD9;bromodomain containing 9,-,"GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0070577//lysine-acetylated histone binding;GO:0003676//nucleic acid binding,-
65981,0,0,0,0,0,0,18,76,73,0,0,0,CAPRIN2;caprin family member 2,GO:0043235//receptor complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0050775//positive regulation of dendrite morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0017148//negative regulation of translation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0032092//positive regulation of protein binding;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0030308//negative regulation of cell growth,GO:0005515//protein binding;GO:0005102//receptor binding;GO:0003723//RNA binding,K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus;K03987//Pertussis;Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection
65982,0,0,0,1,4,34,6,0,17,0,16,0,ZSCAN18;zinc finger and SCAN domain containing 18,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
65983,0,0,0,20,10,27,30,0,1,0,17,0,GRAMD3;GRAM domain containing 3,GO:0005881//cytoplasmic microtubule,-,-,-
65985,82,1,0,35,29,6,54,49,32,131,0,0,AACS;acetoacetyl-CoA synthetase,GO:0005829//cytosol,GO:0045471//response to ethanol;GO:0014074//response to purine-containing compound;GO:0006631//fatty acid metabolic process;GO:0071333//cellular response to glucose stimulus;GO:0060612//adipose tissue development;GO:0071397//cellular response to cholesterol;GO:0007584//response to nutrient;GO:0042594//response to starvation;GO:0001889//liver development;GO:0050872//white fat cell differentiation;GO:0034201//response to oleic acid;GO:0071394//cellular response to testosterone stimulus;GO:0032024//positive regulation of insulin secretion;GO:0042493//response to drug,GO:0030729//acetoacetate-CoA ligase activity;GO:0047760//butyrate-CoA ligase activity;GO:0005524//ATP binding,K01907//Butanoate metabolism
65986,200,113,3,156,614,51,4,0,48,0,17,1,ZBTB10;zinc finger and BTB domain containing 10,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
65987,0,0,0,0,0,0,0,0,0,0,11,0,KCTD14;potassium channel tetramerization domain containing 14,-,GO:0051260//protein homooligomerization,-,K03968//Metabolic pathways;Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation
65988,0,0,0,4,18,4,53,130,14,0,0,0,ZNF747;zinc finger protein 747,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding,-
65989,0,12,18,0,21,0,28,38,17,0,9,0,DLK2;delta-like 2 homolog (Drosophila),GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0045746//negative regulation of Notch signaling pathway;GO:0045598//regulation of fat cell differentiation,GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K06051//Notch signaling pathway
6599,0,33,2,109,271,2,37,0,64,31,9,0,"SMARCC1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1",GO:0043234//protein complex;GO:0071564//npBAF complex;GO:0016514//SWI/SNF complex;GO:0001741//XY body;GO:0071565//nBAF complex;GO:0005730//nucleolus;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006337//nucleosome disassembly;GO:0007399//nervous system development;GO:0008286//insulin receptor signaling pathway;GO:0009887//organ morphogenesis;GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated",GO:0047485//protein N-terminus binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding,-
65991,0,2,38,17,4,14,0,38,12,0,0,0,FUNDC2;FUN14 domain containing 2,GO:0005634//nucleus;GO:0005739//mitochondrion,-,-,-
65992,0,31,0,0,0,0,0,3,27,142,0,129,DDRGK1;DDRGK domain containing 1,GO:0005783//endoplasmic reticulum,-,GO:0005515//protein binding,-
65996,82,2,27,0,0,14,0,59,37,0,0,0,CENPBD1P1;CENPBD1 pseudogene 1,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
65997,0,0,0,0,0,0,0,0,0,0,0,190,"RASL11B;RAS-like, family 11, member B",GO:0016020//membrane,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,-
65998,0,0,0,0,0,9,0,0,1,0,3,0,C11orf95;chromosome 11 open reading frame 95,-,-,-,-
65999,0,0,0,0,1,0,0,0,0,0,0,1,LRRC61;leucine rich repeat containing 61,-,-,-,-
660,0,0,0,0,0,58,0,0,44,0,8,0,BMX;BMX non-receptor tyrosine kinase,GO:0032587//ruffle membrane;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007498//mesoderm development;GO:0035556//intracellular signal transduction;GO:0007155//cell adhesion;GO:0006950//response to stress;GO:0006915//apoptotic process,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004871//signal transducer activity,-
66000,162,0,0,0,0,12,1,0,48,0,0,0,TMEM108;transmembrane protein 108,GO:0016021//integral component of membrane,-,-,-
66002,0,0,0,0,0,0,0,53,20,19,0,0,"CYP4F12;cytochrome P450, family 4, subfamily F, polypeptide 12",GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane,GO:0036101//leukotriene B4 catabolic process;GO:0006805//xenobiotic metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0019373//epoxygenase P450 pathway;GO:0000038//very long-chain fatty acid metabolic process;GO:0055078//sodium ion homeostasis;GO:0042360//vitamin E metabolic process;GO:0042371//vitamin K biosynthetic process;GO:0003091//renal water homeostasis;GO:0030195//negative regulation of blood coagulation;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0017144//drug metabolic process;GO:0003095//pressure natriuresis,GO:0018685//alkane 1-monooxygenase activity;GO:0005506//iron ion binding;GO:0070330//aromatase activity;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0020037//heme binding;GO:0008392//arachidonic acid epoxygenase activity;GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity,K00490//Arachidonic acid metabolism;Metabolic pathways
66004,0,0,0,0,0,13,0,0,20,0,27,0,LYNX1;Ly6/neurotoxin 1,GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0031225//anchored component of membrane,-,-,-
66005,0,0,0,0,0,27,0,0,41,0,0,0,CHID1;chitinase domain containing 1,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005770//late endosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005802//trans-Golgi network;GO:0005764//lysosome,GO:0006032//chitin catabolic process;GO:0045087//innate immune response;GO:1900016//negative regulation of cytokine production involved in inflammatory response;GO:0005975//carbohydrate metabolic process,GO:0005515//protein binding;GO:0004568//chitinase activity;GO:0070492//oligosaccharide binding,-
66008,0,34,1,35,112,1,14,0,85,181,0,0,"TRAK2;trafficking protein, kinesin binding 2",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005886//plasma membrane;GO:0005769//early endosome,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006493//protein O-linked glycosylation;GO:0006605//protein targeting,GO:0005515//protein binding;GO:0050811//GABA receptor binding;GO:0005102//receptor binding;GO:0019899//enzyme binding,K15374//Metabolic pathways;GABAergic synapse
6601,0,57,106,28,99,10,108,0,126,0,37,0,"SMARCC2;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2",GO:0071565//nBAF complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0017053//transcriptional repressor complex;GO:0043234//protein complex;GO:0071564//npBAF complex;GO:0016514//SWI/SNF complex,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006337//nucleosome disassembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021882//regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling",GO:0005515//protein binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity,-
6602,0,0,0,4,62,0,17,22,35,0,14,1,"SMARCD1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1",GO:0071565//nBAF complex;GO:0016514//SWI/SNF complex;GO:0071564//npBAF complex,GO:0006338//chromatin remodeling;GO:0006337//nucleosome disassembly;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048096//chromatin-mediated maintenance of transcription;GO:0007399//nervous system development,GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0032947//protein complex scaffold,-
6603,0,2,0,38,112,0,0,77,3,0,15,0,"SMARCD2;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2",GO:0043234//protein complex;GO:0005634//nucleus;GO:0016514//SWI/SNF complex;GO:0000790//nuclear chromatin,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0043044//ATP-dependent chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0006337//nucleosome disassembly",GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding,-
66035,0,0,0,0,20,0,15,25,17,0,0,0,"SLC2A11;solute carrier family 2 (facilitated glucose transporter), member 11",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0008643//carbohydrate transport,GO:0022891//substrate-specific transmembrane transporter activity,-
66036,66,50,414,34,133,0,44,890,143,4,81,2,MTMR9;myotubularin related protein 9,GO:0005737//cytoplasm,GO:0050790//regulation of catalytic activity;GO:0016311//dephosphorylation,GO:0030234//enzyme regulator activity;GO:0016791//phosphatase activity;GO:0005515//protein binding,K01112//Fructose and mannose metabolism
66037,0,0,0,0,0,28,9,1,76,16,0,266,BOLL;boule-like RNA-binding protein,GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0007126//meiotic nuclear division;GO:0030154//cell differentiation;GO:0045948//positive regulation of translational initiation,GO:0008494//translation activator activity;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003723//RNA binding,K14411//mRNA surveillance pathway
6604,0,0,0,0,1,6,0,0,42,0,0,0,"SMARCD3;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3",GO:0005654//nucleoplasm;GO:0071564//npBAF complex;GO:0016514//SWI/SNF complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0071565//nBAF complex,"GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0003219//cardiac right ventricle formation;GO:0002052//positive regulation of neuroblast proliferation;GO:0006337//nucleosome disassembly;GO:0043393//regulation of protein binding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0003407//neural retina development;GO:0044255//cellular lipid metabolic process;GO:0003139//secondary heart field specification;GO:0044281//small molecule metabolic process;GO:0042692//muscle cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0005102//receptor binding;GO:0008134//transcription factor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0005515//protein binding,-
6605,0,0,1,32,24,20,0,0,18,0,0,0,"SMARCE1;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1",GO:0017053//transcriptional repressor complex;GO:0043234//protein complex;GO:0071564//npBAF complex;GO:0000228//nuclear chromosome;GO:0016514//SWI/SNF complex;GO:0071565//nBAF complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0006337//nucleosome disassembly;GO:0006338//chromatin remodeling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043044//ATP-dependent chromatin remodeling;GO:0007399//nervous system development;GO:0008152//metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0008080//N-acetyltransferase activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003723//RNA binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0016922//ligand-dependent nuclear receptor binding,-
6608,0,0,0,0,0,0,10,0,33,0,6,1,"SMO;smoothened, frizzled class receptor",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0072372//primary cilium;GO:0005929//cilium;GO:0043231//intracellular membrane-bounded organelle;GO:0005901//caveola,GO:0072285//mesenchymal to epithelial transition involved in metanephric renal vesicle formation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001649//osteoblast differentiation;GO:0042307//positive regulation of protein import into nucleus;GO:0007224//smoothened signaling pathway;GO:0007368//determination of left/right symmetry;GO:0048853//forebrain morphogenesis;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway;GO:0050679//positive regulation of epithelial cell proliferation;GO:0010629//negative regulation of gene expression;GO:0007494//midgut development;GO:0031102//neuron projection regeneration;GO:0060644//mammary gland epithelial cell differentiation;GO:0034504//protein localization to nucleus;GO:0051451//myoblast migration;GO:0031076//embryonic camera-type eye development;GO:0048663//neuron fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding;GO:0030857//negative regulation of epithelial cell differentiation;GO:0021561//facial nerve development;GO:0071397//cellular response to cholesterol;GO:0042693//muscle cell fate commitment;GO:0021508//floor plate formation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0048702//embryonic neurocranium morphogenesis;GO:0021938//smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation;GO:0051799//negative regulation of hair follicle development;GO:0021984//adenohypophysis development;GO:0021953//central nervous system neuron differentiation;GO:0031069//hair follicle morphogenesis;GO:0001708//cell fate specification;GO:0060248//detection of cell density by contact stimulus involved in contact inhibition;GO:0021910//smoothened signaling pathway involved in ventral spinal cord patterning;GO:0003323//type B pancreatic cell development;GO:0008406//gonad development;GO:0001755//neural crest cell migration;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0007283//spermatogenesis;GO:2000036//regulation of stem cell maintenance;GO:0009952//anterior/posterior pattern specification;GO:0003007//heart morphogenesis;GO:0048703//embryonic viscerocranium morphogenesis;GO:0060684//epithelial-mesenchymal cell signaling;GO:0021696//cerebellar cortex morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0002052//positive regulation of neuroblast proliferation;GO:0010002//cardioblast differentiation;GO:0048741//skeletal muscle fiber development;GO:2000826//regulation of heart morphogenesis;GO:0032474//otolith morphogenesis;GO:0048846//axon extension involved in axon guidance;GO:0021794//thalamus development;GO:0061053//somite development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0031017//exocrine pancreas development;GO:0007371//ventral midline determination;GO:0060070//canonical Wnt signaling pathway;GO:0035264//multicellular organism growth;GO:0001947//heart looping;GO:0050821//protein stabilization;GO:0007228//positive regulation of hh target transcription factor activity;GO:0021904//dorsal/ventral neural tube patterning;GO:0072001//renal system development;GO:0001701//in utero embryonic development;GO:0061113//pancreas morphogenesis;GO:0003140//determination of left/right asymmetry in lateral mesoderm;GO:0048752//semicircular canal morphogenesis;GO:0060413//atrial septum morphogenesis;GO:0001570//vasculogenesis;GO:0048557//embryonic digestive tract morphogenesis,GO:0005113//patched binding;GO:0017147//Wnt-protein binding;GO:0005515//protein binding;GO:0008144//drug binding;GO:0004930//G-protein coupled receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding,K06226//Basal cell carcinoma;Hedgehog signaling pathway;Pathways in cancer
6609,58,0,0,0,0,0,0,23,0,0,0,0,"SMPD1;sphingomyelin phosphodiesterase 1, acid lysosomal",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0043202//lysosomal lumen;GO:0042599//lamellar body,GO:0035307//positive regulation of protein dephosphorylation;GO:0046513//ceramide biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0043407//negative regulation of MAP kinase activity;GO:0006687//glycosphingolipid metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0006684//sphingomyelin metabolic process;GO:0007399//nervous system development;GO:0008219//cell death;GO:0042493//response to drug;GO:0023021//termination of signal transduction;GO:0006685//sphingomyelin catabolic process;GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0042220//response to cocaine,"GO:0016798//hydrolase activity, acting on glycosyl bonds;GO:0005515//protein binding;GO:0004767//sphingomyelin phosphodiesterase activity",K12350//Lysosome;Sphingolipid metabolism;Metabolic pathways
661,0,35,0,0,0,0,0,0,24,0,0,0,"POLR3D;polymerase (RNA) III (DNA directed) polypeptide D, 44kDa",GO:0005829//cytosol;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex,GO:0032481//positive regulation of type I interferon production;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0032728//positive regulation of interferon-beta production;GO:0045089//positive regulation of innate immune response;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression,GO:0003677//DNA binding;GO:0001056//RNA polymerase III activity;GO:0003682//chromatin binding,K03026//Metabolic pathways;Cytosolic DNA-sensing pathway;Pyrimidine metabolism;Epstein-Barr virus infection;RNA polymerase;Purine metabolism
6610,0,1,44,1,0,10,0,0,0,0,3,1,"SMPD2;sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005901//caveola,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0009612//response to mechanical stimulus;GO:0046513//ceramide biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0006684//sphingomyelin metabolic process;GO:0097190//apoptotic signaling pathway;GO:0006687//glycosphingolipid metabolic process,GO:0046872//metal ion binding;GO:0004767//sphingomyelin phosphodiesterase activity,K12351//Sphingolipid metabolism;Metabolic pathways
6611,61,418,7,492,1065,0,13,2,22,0,3,0,SMS;spermine synthase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006597//spermine biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0006555//methionine metabolic process;GO:0006595//polyamine metabolic process;GO:0044281//small molecule metabolic process,GO:0016768//spermine synthase activity;GO:0004766//spermidine synthase activity,K00802//Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways
6612,0,1,2,49,166,0,15,0,35,4,4,0,SUMO3;small ubiquitin-like modifier 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0000776//kinetochore;GO:0016605//PML body,GO:0034504//protein localization to nucleus;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0043687//post-translational protein modification;GO:0016925//protein sumoylation;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0019789//SUMO ligase activity,K12160//RNA transport
6613,1,17,1,52,206,0,0,0,8,0,1,0,SUMO2;small ubiquitin-like modifier 2,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016605//PML body,GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016925//protein sumoylation,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0031625//ubiquitin protein ligase binding,K12160//RNA transport
6614,1,0,0,0,0,0,0,0,102,0,26,351,"SIGLEC1;sialic acid binding Ig-like lectin 1, sialoadhesin",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0016337//single organismal cell-cell adhesion;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0006954//inflammatory response;GO:0007160//cell-matrix adhesion;GO:0006897//endocytosis;GO:0070234//positive regulation of T cell apoptotic process,GO:0030246//carbohydrate binding,K06548//Cell adhesion molecules (CAMs)
6615,0,0,0,0,0,18,0,0,0,0,0,0,SNAI1;snail family zinc finger 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0060806//negative regulation of cell differentiation involved in embryonic placenta development;GO:0060021//palate development;GO:0030335//positive regulation of cell migration;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000810//regulation of tight junction assembly;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060707//trophoblast giant cell differentiation;GO:0031069//hair follicle morphogenesis;GO:0001707//mesoderm formation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0061314//Notch signaling involved in heart development;GO:0001837//epithelial to mesenchymal transition;GO:0060972//left/right pattern formation;GO:0010957//negative regulation of vitamin D biosynthetic process;GO:0001649//osteoblast differentiation;GO:0060536//cartilage morphogenesis;GO:0016477//cell migration;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator",GO:0019900//kinase binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K05707//Adherens junction
6616,113,0,0,0,0,8,39,0,9,0,0,0,"SNAP25;synaptosomal-associated protein, 25kDa",GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0031083//BLOC-1 complex;GO:0030426//growth cone;GO:0043005//neuron projection;GO:0016020//membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0031201//SNARE complex;GO:0048471//perinuclear region of cytoplasm;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex,GO:0010975//regulation of neuron projection development;GO:0044281//small molecule metabolic process;GO:0070201//regulation of establishment of protein localization;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0014047//glutamate secretion;GO:0060291//long-term synaptic potentiation;GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0001504//neurotransmitter uptake;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0007268//synaptic transmission,GO:0000149//SNARE binding;GO:0005515//protein binding,K08508//SNARE interactions in vesicular transport;Synaptic vesicle cycle
6617,1,0,0,0,0,0,0,0,24,0,11,0,"SNAPC1;small nuclear RNA activating complex, polypeptide 1, 43kDa",GO:0005654//nucleoplasm,"GO:0006383//transcription from RNA polymerase III promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression",GO:0003677//DNA binding,K08268//mTOR signaling pathway;Pathways in cancer;Renal cell carcinoma
6618,23,0,51,8,0,0,0,0,35,0,0,0,"SNAPC2;small nuclear RNA activating complex, polypeptide 2, 45kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0009301//snRNA transcription;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity,-
6619,100,1,0,25,43,0,0,0,29,0,0,0,"SNAPC3;small nuclear RNA activating complex, polypeptide 3, 50kDa",GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0009301//snRNA transcription;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter",GO:0003677//DNA binding,-
662,1,0,0,0,9,0,0,0,13,0,7,0,BNIP1;BCL2/adenovirus E1B 19kDa interacting protein 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0031201//SNARE complex;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0016320//endoplasmic reticulum membrane fusion;GO:0097194//execution phase of apoptosis;GO:0016192//vesicle-mediated transport;GO:0007029//endoplasmic reticulum organization;GO:0006915//apoptotic process;GO:0006914//autophagy;GO:0043066//negative regulation of apoptotic process,GO:0005484//SNAP receptor activity;GO:0005515//protein binding,K08497//SNARE interactions in vesicular transport
6620,0,0,0,0,2,0,0,0,19,0,0,1,"SNCB;synuclein, beta",GO:0043195//terminal bouton;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0016234//inclusion body;GO:0005794//Golgi apparatus,GO:0043524//negative regulation of neuron apoptotic process;GO:0042417//dopamine metabolic process;GO:0043086//negative regulation of catalytic activity;GO:0007268//synaptic transmission;GO:0050808//synapse organization,GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding;GO:0005509//calcium ion binding;GO:0004859//phospholipase inhibitor activity,K04528//Alzheimer's disease;Parkinson's disease
6621,31,0,0,0,0,24,0,0,61,0,14,0,"SNAPC4;small nuclear RNA activating complex, polypeptide 4, 190kDa",GO:0005654//nucleoplasm;GO:0019185//snRNA-activating protein complex;GO:0005634//nucleus,"GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0009301//snRNA transcription;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0042796//snRNA transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006383//transcription from RNA polymerase III promoter",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding,-
6622,0,0,1,12,23,0,37,0,15,0,0,0,"SNCA;synuclein, alpha (non A4 component of amyloid precursor)",GO:0005634//nucleus;GO:0005764//lysosome;GO:0030424//axon;GO:0005840//ribosome;GO:0005938//cell cortex;GO:0031092//platelet alpha granule membrane;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0043205//fibril;GO:0005576//extracellular region;GO:0008021//synaptic vesicle;GO:0005640//nuclear outer membrane;GO:0048471//perinuclear region of cytoplasm;GO:0043195//terminal bouton;GO:0005791//rough endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0016234//inclusion body,GO:0042416//dopamine biosynthetic process;GO:0032026//response to magnesium ion;GO:0070555//response to interleukin-1;GO:0055074//calcium ion homeostasis;GO:0006644//phospholipid metabolic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045963//negative regulation of dopamine metabolic process;GO:0031648//protein destabilization;GO:0048488//synaptic vesicle endocytosis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0032410//negative regulation of transporter activity;GO:0032769//negative regulation of monooxygenase activity;GO:0055114//oxidation-reduction process;GO:0007006//mitochondrial membrane organization;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0042493//response to drug;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070495//negative regulation of thrombin receptor signaling pathway;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0031115//negative regulation of microtubule polymerization;GO:0071280//cellular response to copper ion;GO:0006631//fatty acid metabolic process;GO:0014059//regulation of dopamine secretion;GO:0050808//synapse organization;GO:0032496//response to lipopolysaccharide;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0010040//response to iron(II) ion;GO:0051612//negative regulation of serotonin uptake;GO:0040012//regulation of locomotion;GO:0031623//receptor internalization;GO:0001774//microglial cell activation;GO:0043524//negative regulation of neuron apoptotic process;GO:0007568//aging;GO:0008344//adult locomotory behavior;GO:0034599//cellular response to oxidative stress;GO:0001956//positive regulation of neurotransmitter secretion;GO:0043030//regulation of macrophage activation;GO:0045807//positive regulation of endocytosis;GO:0051583//dopamine uptake involved in synaptic transmission;GO:0034341//response to interferon-gamma;GO:0060732//positive regulation of inositol phosphate biosynthetic process;GO:0060291//long-term synaptic potentiation;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0001921//positive regulation of receptor recycling;GO:0048148//behavioral response to cocaine;GO:0045920//negative regulation of exocytosis;GO:0043206//extracellular fibril organization;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035067//negative regulation of histone acetylation;GO:1901214//regulation of neuron death;GO:0051585//negative regulation of dopamine uptake involved in synaptic transmission;GO:0043066//negative regulation of apoptotic process;GO:0010517//regulation of phospholipase activity;GO:0071872//cellular response to epinephrine stimulus;GO:0006638//neutral lipid metabolic process;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0001933//negative regulation of protein phosphorylation;GO:0051622//negative regulation of norepinephrine uptake,GO:0045502//dynein binding;GO:0008017//microtubule binding;GO:0000287//magnesium ion binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0043014//alpha-tubulin binding;GO:0016491//oxidoreductase activity;GO:0051219//phosphoprotein binding;GO:0005509//calcium ion binding;GO:0019894//kinesin binding;GO:0005543//phospholipid binding;GO:0048487//beta-tubulin binding;GO:0047485//protein N-terminus binding;GO:0019904//protein domain specific binding;GO:0043274//phospholipase binding;GO:0060961//phospholipase D inhibitor activity;GO:0030544//Hsp70 protein binding;GO:0008198//ferrous iron binding;GO:0042802//identical protein binding;GO:0005504//fatty acid binding;GO:0005507//copper ion binding;GO:0048156//tau protein binding;GO:0005515//protein binding;GO:0042393//histone binding;GO:0008270//zinc ion binding,K04528//Alzheimer's disease;Parkinson's disease
6623,65,0,0,0,0,0,0,0,0,0,0,0,"SNCG;synuclein, gamma (breast cancer-specific protein 1)",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005819//spindle;GO:0043025//neuronal cell body;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0048471//perinuclear region of cytoplasm,GO:0002118//aggressive behavior;GO:0046928//regulation of neurotransmitter secretion;GO:0042493//response to drug;GO:0008344//adult locomotory behavior;GO:0042220//response to cocaine;GO:0007268//synaptic transmission;GO:0050808//synapse organization;GO:0071464//cellular response to hydrostatic pressure;GO:0009306//protein secretion;GO:0014059//regulation of dopamine secretion,GO:0043014//alpha-tubulin binding;GO:0048487//beta-tubulin binding,K04528//Parkinson's disease;Alzheimer's disease
6624,0,0,0,0,0,17,44,2,13,0,0,0,FSCN1;fascin actin-bundling protein 1,GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0001725//stress fiber;GO:0071437//invadopodium;GO:0070062//extracellular vesicular exosome;GO:0030175//filopodium;GO:0030054//cell junction;GO:0005737//cytoplasm,GO:0048870//cell motility;GO:0051017//actin filament bundle assembly;GO:0030036//actin cytoskeleton organization;GO:0016477//cell migration;GO:0008283//cell proliferation,"GO:0008144//drug binding;GO:0003779//actin binding;GO:0030674//protein binding, bridging;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0051015//actin filament binding",-
6626,0,26,40,0,19,0,28,0,17,0,32,0,SNRPA;small nuclear ribonucleoprotein polypeptide A,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005685//U1 snRNP;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0005730//nucleolus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome",GO:0017069//snRNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K11091//Spliceosome
6627,0,1,0,0,1,8,0,0,15,0,0,0,SNRPA1;small nuclear ribonucleoprotein polypeptide A',GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0005686//U2 snRNP;GO:0030532//small nuclear ribonucleoprotein complex;GO:0071013//catalytic step 2 spliceosome,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000398//mRNA splicing, via spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11092//Spliceosome
6628,0,10,0,7,30,18,0,0,24,0,0,14,SNRPB;small nuclear ribonucleoprotein polypeptides B and B1,GO:0071204//histone pre-mRNA 3'end processing complex;GO:0005687//U4 snRNP;GO:0005685//U1 snRNP;GO:0034709//methylosome;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005689//U12-type spliceosomal complex;GO:0005654//nucleoplasm;GO:0005683//U7 snRNP;GO:0071013//catalytic step 2 spliceosome;GO:0034719//SMN-Sm protein complex;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex,"GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0071208//histone pre-mRNA DCP binding,K11086//Systemic lupus erythematosus;Spliceosome
6629,0,0,0,12,40,0,0,76,16,0,0,0,SNRPB2;small nuclear ribonucleoprotein polypeptide B,GO:0005681//spliceosomal complex;GO:0005686//U2 snRNP;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome",GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0017069//snRNA binding,K11094//Spliceosome
663,0,0,1,24,32,15,0,0,19,0,0,0,BNIP2;BCL2/adenovirus E1B 19kDa interacting protein 2,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle,GO:0006915//apoptotic process;GO:0051149//positive regulation of muscle cell differentiation;GO:0043547//positive regulation of GTPase activity;GO:0043066//negative regulation of apoptotic process;GO:0042692//muscle cell differentiation,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005096//GTPase activator activity,K01514//Purine metabolism
6631,0,0,0,20,4,0,12,0,19,0,0,0,SNRPC;small nuclear ribonucleoprotein polypeptide C,GO:0005730//nucleolus;GO:0005685//U1 snRNP;GO:0071004//U2-type prespliceosome;GO:0005634//nucleus;GO:0000243//commitment complex;GO:0015030//Cajal body,"GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0000395//mRNA 5'-splice site recognition",GO:0030619//U1 snRNA binding;GO:0008270//zinc ion binding;GO:0003729//mRNA binding;GO:0003727//single-stranded RNA binding;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11095//Spliceosome
6632,0,1,1,2,51,0,0,0,0,0,2,0,SNRPD1;small nuclear ribonucleoprotein D1 polypeptide 16kDa,GO:0005687//U4 snRNP;GO:0005685//U1 snRNP;GO:0034709//methylosome;GO:0005634//nucleus;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0005689//U12-type spliceosomal complex;GO:0005654//nucleoplasm;GO:0034719//SMN-Sm protein complex;GO:0071013//catalytic step 2 spliceosome;GO:0034715//pICln-Sm protein complex,"GO:0000398//mRNA splicing, via spliceosome;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000245//spliceosomal complex assembly;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0016070//RNA metabolic process",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K11087//Spliceosome;Systemic lupus erythematosus
6633,0,46,1,20,53,0,22,0,0,0,0,0,SNRPD2;small nuclear ribonucleoprotein D2 polypeptide 16.5kDa,GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0034715//pICln-Sm protein complex;GO:0034719//SMN-Sm protein complex;GO:0071013//catalytic step 2 spliceosome;GO:0005685//U1 snRNP;GO:0034709//methylosome;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex,"GO:0016070//RNA metabolic process;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0000245//spliceosomal complex assembly;GO:0000387//spliceosomal snRNP assembly;GO:0034660//ncRNA metabolic process;GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K11096//Spliceosome
6634,0,295,62,262,641,23,0,47,78,322,138,0,SNRPD3;small nuclear ribonucleoprotein D3 polypeptide 18kDa,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0034715//pICln-Sm protein complex;GO:0005685//U1 snRNP;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005683//U7 snRNP;GO:0071013//catalytic step 2 spliceosome;GO:0034719//SMN-Sm protein complex;GO:0034709//methylosome;GO:0005687//U4 snRNP;GO:0005689//U12-type spliceosomal complex;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex,"GO:0016070//RNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process;GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006366//transcription from RNA polymerase II promoter;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome",GO:0071208//histone pre-mRNA DCP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0019899//enzyme binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11088//Spliceosome;Systemic lupus erythematosus
6635,0,9,0,21,84,0,0,0,5,0,0,0,SNRPE;small nuclear ribonucleoprotein polypeptide E,GO:0005654//nucleoplasm;GO:0005683//U7 snRNP;GO:0071013//catalytic step 2 spliceosome;GO:0034719//SMN-Sm protein complex;GO:0070062//extracellular vesicular exosome;GO:0005681//spliceosomal complex;GO:0034715//pICln-Sm protein complex;GO:0005687//U4 snRNP;GO:0005685//U1 snRNP;GO:0005634//nucleus;GO:0034709//methylosome;GO:0005829//cytosol;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005689//U12-type spliceosomal complex,"GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0016070//RNA metabolic process;GO:0034660//ncRNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly;GO:0000245//spliceosomal complex assembly;GO:0006366//transcription from RNA polymerase II promoter;GO:0042633//hair cycle;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription",GO:0005515//protein binding;GO:0003723//RNA binding,K11097//Spliceosome
6636,0,18,0,38,35,0,12,0,0,0,0,281,SNRPF;small nuclear ribonucleoprotein polypeptide F,GO:0071013//catalytic step 2 spliceosome;GO:0034719//SMN-Sm protein complex;GO:0034715//pICln-Sm protein complex;GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0005683//U7 snRNP;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0005689//U12-type spliceosomal complex;GO:0005687//U4 snRNP;GO:0034709//methylosome;GO:0005685//U1 snRNP,"GO:0000387//spliceosomal snRNP assembly;GO:0034660//ncRNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0006369//termination of RNA polymerase II transcription;GO:0031124//mRNA 3'-end processing;GO:0008334//histone mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0003723//RNA binding;GO:0005515//protein binding,K11098//Spliceosome
6637,0,49,0,26,78,0,0,0,0,0,0,0,SNRPG;small nuclear ribonucleoprotein polypeptide G,GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0034719//SMN-Sm protein complex;GO:0005683//U7 snRNP;GO:0005654//nucleoplasm;GO:0005689//U12-type spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0005685//U1 snRNP;GO:0034709//methylosome;GO:0005687//U4 snRNP,"GO:0016070//RNA metabolic process;GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter;GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K11099//Spliceosome
6638,0,0,0,0,1,13,0,0,0,0,0,0,SNRPN;small nuclear ribonucleoprotein polypeptide N,GO:0005685//U1 snRNP;GO:0005686//U2 snRNP;GO:0005681//spliceosomal complex;GO:0030532//small nuclear ribonucleoprotein complex,GO:0008380//RNA splicing;GO:0009725//response to hormone,GO:0005515//protein binding;GO:0003723//RNA binding,-
664,0,49,4,64,92,1,8,0,0,0,14,2,BNIP3;BCL2/adenovirus E1B 19kDa interacting protein 3,GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005737//cytoplasm;GO:0031307//integral component of mitochondrial outer membrane;GO:0005654//nucleoplasm;GO:0005741//mitochondrial outer membrane;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum,GO:0048102//autophagic cell death;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0050873//brown fat cell differentiation;GO:0043068//positive regulation of programmed cell death;GO:0043243//positive regulation of protein complex disassembly;GO:0071260//cellular response to mechanical stimulus;GO:0043065//positive regulation of apoptotic process;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0071279//cellular response to cobalt ion;GO:0097345//mitochondrial outer membrane permeabilization;GO:0043653//mitochondrial fragmentation involved in apoptotic process;GO:0010637//negative regulation of mitochondrial fusion;GO:0051402//neuron apoptotic process;GO:0046902//regulation of mitochondrial membrane permeability;GO:0008626//granzyme-mediated apoptotic signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:1990144//intrinsic apoptotic signaling pathway in response to hypoxia;GO:0043066//negative regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0035694//mitochondrial protein catabolic process;GO:0008219//cell death;GO:0072593//reactive oxygen species metabolic process;GO:0045837//negative regulation of membrane potential;GO:0071456//cellular response to hypoxia;GO:0055093//response to hyperoxia;GO:0010508//positive regulation of autophagy;GO:0090141//positive regulation of mitochondrial fission,GO:0051020//GTPase binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,K15464//Legionellosis
6640,0,0,0,0,0,0,0,53,44,0,12,538,"SNTA1;syntrophin, alpha 1",GO:0005622//intracellular;GO:0042383//sarcolemma;GO:0016013//syntrophin complex;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0016328//lateral plasma membrane;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0007528//neuromuscular junction development;GO:0086005//ventricular cardiac muscle cell action potential;GO:0003117//regulation of vasoconstriction by circulating norepinephrine;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0006936//muscle contraction;GO:1902083//negative regulation of peptidyl-cysteine S-nitrosylation;GO:0002027//regulation of heart rate;GO:1902305//regulation of sodium ion transmembrane transport,GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0030165//PDZ domain binding;GO:0017080//sodium channel regulator activity;GO:0051117//ATPase binding;GO:0003779//actin binding;GO:0050998//nitric-oxide synthase binding;GO:0005516//calmodulin binding,K14548//Ribosome biogenesis in eukaryotes;K12196//Endocytosis
6641,13,0,0,0,0,0,0,1,49,0,1,0,"SNTB1;syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)",GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0045202//synapse;GO:0016010//dystrophin-associated glycoprotein complex;GO:0042383//sarcolemma,GO:0006936//muscle contraction,GO:0003779//actin binding;GO:0005516//calmodulin binding;GO:0030165//PDZ domain binding;GO:0005515//protein binding,K12076//T cell receptor signaling pathway;HTLV-I infection;K12196//Endocytosis
6642,95,53,1,48,171,15,1,42,11,0,4,0,SNX1;sorting nexin 1,GO:0043234//protein complex;GO:0030904//retromer complex;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane,GO:0006886//intracellular protein transport;GO:0045732//positive regulation of protein catabolic process;GO:0034498//early endosome to Golgi transport,GO:0005158//insulin receptor binding;GO:0005154//epidermal growth factor receptor binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer
6643,0,0,0,16,111,23,19,0,52,0,20,0,SNX2;sorting nexin 2,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0030904//retromer complex;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane,GO:0006886//intracellular protein transport;GO:0006897//endocytosis;GO:0051259//protein oligomerization,GO:0005154//epidermal growth factor receptor binding;GO:0005158//insulin receptor binding;GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding,K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
6645,0,34,0,13,138,17,1,21,90,0,17,0,"SNTB2;syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)",GO:0005874//microtubule;GO:0005925//focal adhesion;GO:0043234//protein complex;GO:0030658//transport vesicle membrane;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0016010//dystrophin-associated glycoprotein complex;GO:0045202//synapse;GO:0070062//extracellular vesicular exosome,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005516//calmodulin binding,K12196//Endocytosis;K11447//Transcriptional misregulation in cancer
6646,0,14,16,34,26,27,5,0,10,0,0,0,SOAT1;sterol O-acyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0033344//cholesterol efflux;GO:0010878//cholesterol storage;GO:0034379//very-low-density lipoprotein particle assembly;GO:0034435//cholesterol esterification;GO:0042986//positive regulation of amyloid precursor protein biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0042632//cholesterol homeostasis;GO:0010742//macrophage derived foam cell differentiation,GO:0015485//cholesterol binding;GO:0034736//cholesterol O-acyltransferase activity;GO:0005515//protein binding;GO:0000062//fatty-acyl-CoA binding,K00637//Steroid biosynthesis
664612,0,0,0,0,0,0,0,29,0,0,0,0,MIR539;microRNA 539,-,-,-,-
664616,0,0,0,0,0,0,0,0,0,18,0,0,MIR487B;microRNA 487b,-,-,-,-
664617,2,0,0,0,0,0,0,0,0,0,0,0,MIR542;microRNA 542,-,-,-,-
6647,0,211,2,171,297,0,0,0,0,0,0,0,"SOD1;superoxide dismutase 1, soluble",GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0005777//peroxisome;GO:0031410//cytoplasmic vesicle;GO:0043234//protein complex;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane;GO:0032839//dendrite cytoplasm;GO:0031012//extracellular matrix;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0032930//positive regulation of superoxide anion generation;GO:0019226//transmission of nerve impulse;GO:0045541//negative regulation of cholesterol biosynthetic process;GO:0042542//response to hydrogen peroxide;GO:0050665//hydrogen peroxide biosynthetic process;GO:0006801//superoxide metabolic process;GO:0001890//placenta development;GO:0060088//auditory receptor cell stereocilium organization;GO:0007566//embryo implantation;GO:0007626//locomotory behavior;GO:0002262//myeloid cell homeostasis;GO:0072593//reactive oxygen species metabolic process;GO:0032287//peripheral nervous system myelin maintenance;GO:0051881//regulation of mitochondrial membrane potential;GO:0007596//blood coagulation;GO:0060087//relaxation of vascular smooth muscle;GO:0031667//response to nutrient levels;GO:0033081//regulation of T cell differentiation in thymus;GO:0048678//response to axon injury;GO:0007283//spermatogenesis;GO:0002576//platelet degranulation;GO:0008090//retrograde axon cargo transport;GO:0043524//negative regulation of neuron apoptotic process;GO:0040014//regulation of multicellular organism growth;GO:0032314//regulation of Rac GTPase activity;GO:0046688//response to copper ion;GO:0030168//platelet activation;GO:0001819//positive regulation of cytokine production;GO:0009408//response to heat;GO:0000187//activation of MAPK activity;GO:0045471//response to ethanol;GO:0060047//heart contraction;GO:0008219//cell death;GO:0042493//response to drug;GO:0007605//sensory perception of sound;GO:0048538//thymus development;GO:0010033//response to organic substance;GO:0006879//cellular iron ion homeostasis;GO:0019430//removal of superoxide radicals;GO:0008089//anterograde axon cargo transport;GO:0006749//glutathione metabolic process;GO:0055114//oxidation-reduction process;GO:0001541//ovarian follicle development;GO:0001895//retina homeostasis;GO:0042554//superoxide anion generation;GO:0007569//cell aging;GO:0046716//muscle cell cellular homeostasis;GO:0008217//regulation of blood pressure;GO:0043085//positive regulation of catalytic activity;GO:1902177//positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0046620//regulation of organ growth;GO:0001975//response to amphetamine;GO:0060052//neurofilament cytoskeleton organization;GO:0045859//regulation of protein kinase activity;GO:0000303//response to superoxide,GO:0042802//identical protein binding;GO:0048365//Rac GTPase binding;GO:0004784//superoxide dismutase activity;GO:0030346//protein phosphatase 2B binding;GO:0051087//chaperone binding;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005507//copper ion binding,K04565//Amyotrophic lateral sclerosis (ALS);Huntington's disease;Prion diseases;Peroxisome
6648,109,30,0,19,60,0,0,0,16,0,0,0,"SOD2;superoxide dismutase 2, mitochondrial",GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,GO:0030097//hemopoiesis;GO:0051881//regulation of mitochondrial membrane potential;GO:0048678//response to axon injury;GO:0003069//vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0010043//response to zinc ion;GO:0022904//respiratory electron transport chain;GO:0043524//negative regulation of neuron apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050790//regulation of catalytic activity;GO:0009791//post-embryonic development;GO:0010269//response to selenium ion;GO:0051602//response to electrical stimulus;GO:0014823//response to activity;GO:0008285//negative regulation of cell proliferation;GO:0050665//hydrogen peroxide biosynthetic process;GO:0006801//superoxide metabolic process;GO:0042542//response to hydrogen peroxide;GO:0007626//locomotory behavior;GO:0048666//neuron development;GO:0001889//liver development;GO:0007507//heart development;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0008217//regulation of blood pressure;GO:0001666//response to hypoxia;GO:0006749//glutathione metabolic process;GO:0042554//superoxide anion generation;GO:0048773//erythrophore differentiation;GO:0032364//oxygen homeostasis;GO:0048147//negative regulation of fibroblast proliferation;GO:0003032//detection of oxygen;GO:0010042//response to manganese ion;GO:0001836//release of cytochrome c from mitochondria;GO:0000303//response to superoxide;GO:0046686//response to cadmium ion;GO:0010332//response to gamma radiation;GO:0032496//response to lipopolysaccharide;GO:0055072//iron ion homeostasis;GO:0071361//cellular response to ethanol;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045599//negative regulation of fat cell differentiation;GO:0001315//age-dependent response to reactive oxygen species;GO:0042493//response to drug;GO:0051289//protein homotetramerization;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0019430//removal of superoxide radicals;GO:0033591//response to L-ascorbic acid;GO:0034021//response to silicon dioxide;GO:0055093//response to hyperoxia,GO:0003677//DNA binding;GO:0030145//manganese ion binding;GO:0042802//identical protein binding;GO:0004784//superoxide dismutase activity;GO:0019825//oxygen binding,K04564//Peroxisome;Huntington's disease
6649,0,0,0,0,0,0,0,1,7,0,16,21,"SOD3;superoxide dismutase 3, extracellular",GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0005796//Golgi lumen,GO:0046688//response to copper ion;GO:0019430//removal of superoxide radicals;GO:0055114//oxidation-reduction process;GO:0001666//response to hypoxia,GO:0005507//copper ion binding;GO:0004784//superoxide dismutase activity;GO:0008270//zinc ion binding;GO:0008201//heparin binding;GO:0005515//protein binding,-
665,0,82,2,135,343,0,0,137,0,0,0,0,BNIP3L;BCL2/adenovirus E1B 19kDa interacting protein 3-like,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005741//mitochondrial outer membrane;GO:0031224//intrinsic component of membrane;GO:0005635//nuclear envelope,GO:0043065//positive regulation of apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0097345//mitochondrial outer membrane permeabilization;GO:0035694//mitochondrial protein catabolic process;GO:0051607//defense response to virus;GO:0016032//viral process,GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005521//lamin binding,-
6650,0,0,0,0,10,0,0,0,64,0,16,0,CAPN15;calpain 15,GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006508//proteolysis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008234//cysteine-type peptidase activity;GO:0008270//zinc ion binding;GO:0008233//peptidase activity;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,-
6651,0,42,0,55,351,10,39,1,106,0,0,0,SON;SON DNA binding protein,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus,GO:0043484//regulation of RNA splicing;GO:0000910//cytokinesis;GO:0006397//mRNA processing;GO:0000226//microtubule cytoskeleton organization;GO:0043066//negative regulation of apoptotic process;GO:0008380//RNA splicing;GO:0051726//regulation of cell cycle,GO:0050733//RS domain binding;GO:0003723//RNA binding;GO:0003676//nucleic acid binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K06237//Small cell lung cancer;Protein digestion and absorption;Amoebiasis;Focal adhesion;Pathways in cancer;ECM-receptor interaction;K13908//Salivary secretion
6652,1,594,8,608,1776,0,28,3,23,0,4,505,SORD;sorbitol dehydrogenase,GO:0016020//membrane;GO:0031966//mitochondrial membrane;GO:0005615//extracellular space;GO:0031514//motile cilium;GO:0070062//extracellular vesicular exosome,GO:0046370//fructose biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006062//sorbitol catabolic process;GO:0006006//glucose metabolic process;GO:0051160//L-xylitol catabolic process;GO:0030317//sperm motility,GO:0030246//carbohydrate binding;GO:0008270//zinc ion binding;GO:0051287//NAD binding;GO:0003939//L-iditol 2-dehydrogenase activity,K00008//Ribosome;Metabolic pathways;Fructose and mannose metabolism
6653,188,0,0,11,78,65,66,0,120,1,34,338,"SORL1;sortilin-related receptor, L(DLR class) A repeats containing",GO:0043025//neuronal cell body;GO:0005802//trans-Golgi network;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005641//nuclear envelope lumen;GO:0031985//Golgi cisterna;GO:0055037//recycling endosome;GO:0005887//integral component of plasma membrane;GO:0005771//multivesicular body;GO:0034362//low-density lipoprotein particle;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:1902997//negative regulation of neurofibrillary tangle assembly;GO:0016477//cell migration;GO:0014910//regulation of smooth muscle cell migration;GO:2001137//positive regulation of endocytic recycling;GO:0051604//protein maturation;GO:0006869//lipid transport;GO:0006898//receptor-mediated endocytosis;GO:0000042//protein targeting to Golgi;GO:1902771//positive regulation of choline O-acetyltransferase activity;GO:0043407//negative regulation of MAP kinase activity;GO:0050768//negative regulation of neurogenesis;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902966//positive regulation of protein localization to early endosome;GO:0070863//positive regulation of protein exit from endoplasmic reticulum;GO:1902955//positive regulation of early endosome to recycling endosome transport;GO:0032460//negative regulation of protein oligomerization;GO:0045732//positive regulation of protein catabolic process;GO:1902953//positive regulation of ER to Golgi vesicle-mediated transport;GO:0008219//cell death;GO:0045053//protein retention in Golgi apparatus;GO:1902960//negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:1902430//negative regulation of beta-amyloid formation;GO:1902948//negative regulation of tau-protein kinase activity;GO:0032091//negative regulation of protein binding;GO:0008203//cholesterol metabolic process;GO:0006605//protein targeting;GO:0006622//protein targeting to lysosome;GO:0008283//cell proliferation;GO:0006892//post-Golgi vesicle-mediated transport;GO:1901215//negative regulation of neuron death,GO:0001540//beta-amyloid binding;GO:0004888//transmembrane signaling receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0005515//protein binding;GO:0030306//ADP-ribosylation factor binding,K04550//Alzheimer's disease;Malaria
6654,0,0,0,44,112,20,1,0,16,0,0,0,SOS1;son of sevenless homolog 1 (Drosophila),GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body,GO:0051057//positive regulation of small GTPase mediated signal transduction;GO:0007265//Ras protein signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007411//axon guidance;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0030168//platelet activation;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007596//blood coagulation;GO:0032320//positive regulation of Ras GTPase activity,GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0003677//DNA binding;GO:0017124//SH3 domain binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity;GO:0046982//protein heterodimerization activity,K03099//B cell receptor signaling pathway;Acute myeloid leukemia;Jak-STAT signaling pathway;Fc epsilon RI signaling pathway;Dorso-ventral axis formation;Focal adhesion;Glioma;Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;MAPK signaling pathway - fly;Endometrial cancer;Non-small cell lung cancer;Alcoholism;Prostate cancer;Insulin signaling pathway;Pathways in cancer;GnRH signaling pathway;Chemokine signaling pathway;Gap junction;Renal cell carcinoma;ErbB signaling pathway;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway
6655,0,0,0,39,84,4,0,1,33,0,0,0,SOS2;son of sevenless homolog 2 (Drosophila),GO:0005829//cytosol,GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0007411//axon guidance;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0051057//positive regulation of small GTPase mediated signal transduction,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K03099//Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;MAPK signaling pathway - fly;Endometrial cancer;Non-small cell lung cancer;Dorso-ventral axis formation;Focal adhesion;Glioma;Jak-STAT signaling pathway;Acute myeloid leukemia;Fc epsilon RI signaling pathway;B cell receptor signaling pathway;Chronic myeloid leukemia;T cell receptor signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Renal cell carcinoma;ErbB signaling pathway;Insulin signaling pathway;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Gap junction;Alcoholism;Prostate cancer
6656,244,0,0,0,0,0,0,6,21,0,8,0,SOX1;SRY (sex determining region Y)-box 1,GO:0005634//nucleus,"GO:0001764//neuron migration;GO:0021884//forebrain neuron development;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0021521//ventral spinal cord interneuron specification;GO:0006325//chromatin organization;GO:0002089//lens morphogenesis in camera-type eye",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0001046//core promoter sequence-specific DNA binding,-
6657,0,0,0,0,0,0,0,0,11,0,0,7,SOX2;SRY (sex determining region Y)-box 2,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0021987//cerebral cortex development;GO:0021781//glial cell fate commitment;GO:0001649//osteoblast differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0009611//response to wounding;GO:0007050//cell cycle arrest;GO:0048839//inner ear development;GO:0045666//positive regulation of neuron differentiation;GO:0035019//somatic stem cell maintenance;GO:0001714//endodermal cell fate specification;GO:0001654//eye development;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097150//neuronal stem cell maintenance;GO:0002052//positive regulation of neuroblast proliferation;GO:0043410//positive regulation of MAPK cascade;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042472//inner ear morphogenesis;GO:0030539//male genitalia development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0045668//negative regulation of osteoblast differentiation;GO:0050973//detection of mechanical stimulus involved in equilibrioception;GO:0006366//transcription from RNA polymerase II promoter;GO:0010468//regulation of gene expression;GO:0045747//positive regulation of Notch signaling pathway;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0070848//response to growth factor;GO:0021879//forebrain neuron differentiation;GO:0048663//neuron fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032526//response to retinoic acid;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030910//olfactory placode formation;GO:0060042//retina morphogenesis in camera-type eye;GO:0045665//negative regulation of neuron differentiation;GO:0046148//pigment biosynthetic process;GO:0048852//diencephalon morphogenesis;GO:0021984//adenohypophysis development;GO:0030900//forebrain development;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060235//lens induction in camera-type eye;GO:0048286//lung alveolus development;GO:0021983//pituitary gland development;GO:0006355//regulation of transcription, DNA-templated;GO:0043586//tongue development",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0035198//miRNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,-
6658,0,0,0,0,0,0,0,0,26,0,0,0,SOX3;SRY (sex determining region Y)-box 3,GO:0005634//nucleus,"GO:0060009//Sertoli cell development;GO:0007530//sex determination;GO:0021983//pituitary gland development;GO:0048666//neuron development;GO:0045665//negative regulation of neuron differentiation;GO:0006351//transcription, DNA-templated;GO:0021854//hypothalamus development;GO:0009887//organ morphogenesis;GO:0060324//face development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007417//central nervous system development;GO:0007423//sensory organ development;GO:0048515//spermatid differentiation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0003677//DNA binding,-
6659,85,0,22,3,155,0,0,63,34,0,0,0,SOX4;SRY (sex determining region Y)-box 4,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0044798//nuclear transcription factor complex;GO:0005730//nucleolus;GO:0005739//mitochondrion,"GO:0001841//neural tube formation;GO:0060993//kidney morphogenesis;GO:0031647//regulation of protein stability;GO:0050821//protein stabilization;GO:0060070//canonical Wnt signaling pathway;GO:0060174//limb bud formation;GO:0042769//DNA damage response, detection of DNA damage;GO:0006355//regulation of transcription, DNA-templated;GO:0021782//glial cell development;GO:0030217//T cell differentiation;GO:0035910//ascending aorta morphogenesis;GO:0048485//sympathetic nervous system development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0060563//neuroepithelial cell differentiation;GO:0030177//positive regulation of Wnt signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0031397//negative regulation of protein ubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0003211//cardiac ventricle formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045727//positive regulation of translation;GO:0003215//cardiac right ventricle morphogenesis;GO:0008285//negative regulation of cell proliferation;GO:0021522//spinal cord motor neuron differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0007507//heart development;GO:0042593//glucose homeostasis;GO:0021510//spinal cord development;GO:0008284//positive regulation of cell proliferation;GO:0014009//glial cell proliferation;GO:0071333//cellular response to glucose stimulus;GO:0060548//negative regulation of cell death;GO:0046826//negative regulation of protein export from nucleus;GO:0002328//pro-B cell differentiation;GO:0003289//atrial septum primum morphogenesis;GO:0001501//skeletal system development;GO:0003183//mitral valve morphogenesis;GO:0035019//somatic stem cell maintenance;GO:0031018//endocrine pancreas development;GO:0003357//noradrenergic neuron differentiation;GO:0032024//positive regulation of insulin secretion;GO:0060412//ventricular septum morphogenesis",GO:0001105//RNA polymerase II transcription coactivator activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001071//nucleic acid binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
666,0,0,0,0,7,7,0,0,14,0,10,0,BOK;BCL2-related ovarian killer,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0005741//mitochondrial outer membrane,GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0051402//neuron apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0008584//male gonad development;GO:0007420//brain development;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0048709//oligodendrocyte differentiation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1900119//positive regulation of execution phase of apoptosis;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator,GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0051400//BH domain binding,-
6660,0,0,0,0,0,40,22,0,19,0,0,0,SOX5;SRY (sex determining region Y)-box 5,GO:0044798//nuclear transcription factor complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0060164//regulation of timing of neuron differentiation;GO:0021953//central nervous system neuron differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048709//oligodendrocyte differentiation;GO:0001701//in utero embryonic development;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0032332//positive regulation of chondrocyte differentiation;GO:0051216//cartilage development;GO:0061036//positive regulation of cartilage development",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0044212//transcription regulatory region DNA binding,-
6662,0,22,1,38,147,10,0,0,18,0,29,0,SOX9;SRY (sex determining region Y)-box 9,GO:0043234//protein complex;GO:0044798//nuclear transcription factor complex;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0072289//metanephric nephron tubule formation;GO:0042127//regulation of cell proliferation;GO:0060517//epithelial cell proliferation involved in prostatic bud elongation;GO:0031018//endocrine pancreas development;GO:0060008//Sertoli cell differentiation;GO:0071347//cellular response to interleukin-1;GO:0001502//cartilage condensation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0070168//negative regulation of biomineral tissue development;GO:0035622//intrahepatic bile duct development;GO:0007283//spermatogenesis;GO:0060009//Sertoli cell development;GO:0008284//positive regulation of cell proliferation;GO:0001894//tissue homeostasis;GO:2000741//positive regulation of mesenchymal stem cell differentiation;GO:0006334//nucleosome assembly;GO:0001942//hair follicle development;GO:0030903//notochord development;GO:0061138//morphogenesis of a branching epithelium;GO:0030858//positive regulation of epithelial cell differentiation;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0003179//heart valve morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0072197//ureter morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0060018//astrocyte fate commitment;GO:0042981//regulation of apoptotic process;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0061036//positive regulation of cartilage development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010634//positive regulation of epithelial cell migration;GO:0030879//mammary gland development;GO:0071260//cellular response to mechanical stimulus;GO:0060784//regulation of cell proliferation involved in tissue homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030502//negative regulation of bone mineralization;GO:0045662//negative regulation of myoblast differentiation;GO:0001503//ossification;GO:0045732//positive regulation of protein catabolic process;GO:0046533//negative regulation of photoreceptor cell differentiation;GO:0060174//limb bud formation;GO:0003188//heart valve formation;GO:0090184//positive regulation of kidney development;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0003170//heart valve development;GO:0019933//cAMP-mediated signaling;GO:0071504//cellular response to heparin;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048709//oligodendrocyte differentiation;GO:0060041//retina development in camera-type eye;GO:0035019//somatic stem cell maintenance;GO:0090103//cochlea morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0006338//chromatin remodeling;GO:0001501//skeletal system development;GO:0030155//regulation of cell adhesion;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0008584//male gonad development;GO:0001934//positive regulation of protein phosphorylation;GO:0043491//protein kinase B signaling;GO:0006461//protein complex assembly;GO:0051216//cartilage development;GO:0072190//ureter urothelium development;GO:0030850//prostate gland development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0072034//renal vesicle induction;GO:0030857//negative regulation of epithelial cell differentiation;GO:2000020//positive regulation of male gonad development;GO:0060487//lung epithelial cell differentiation;GO:0014032//neural crest cell development;GO:0003415//chondrocyte hypertrophy;GO:0060729//intestinal epithelial structure maintenance;GO:0060221//retinal rod cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:1901203//positive regulation of extracellular matrix assembly;GO:0006468//protein phosphorylation;GO:0002683//negative regulation of immune system process;GO:0010564//regulation of cell cycle process;GO:2000138//positive regulation of cell proliferation involved in heart morphogenesis;GO:0070371//ERK1 and ERK2 cascade;GO:0030198//extracellular matrix organization;GO:0030279//negative regulation of ossification;GO:0030916//otic vesicle formation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0019100//male germ-line sex determination;GO:0001708//cell fate specification;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0032332//positive regulation of chondrocyte differentiation;GO:0072193//ureter smooth muscle cell differentiation;GO:0007010//cytoskeleton organization;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0003203//endocardial cushion morphogenesis",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0004672//protein kinase activity;GO:0034236//protein kinase A catalytic subunit binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0097157//pre-mRNA intronic binding;GO:0043425//bHLH transcription factor binding;GO:0008013//beta-catenin binding;GO:0003682//chromatin binding;GO:0035326//enhancer binding,-
6663,0,0,0,8,0,15,0,0,0,0,0,0,SOX10;SRY (sex determining region Y)-box 10,GO:0031315//extrinsic component of mitochondrial outer membrane;GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0001755//neural crest cell migration;GO:0014015//positive regulation of gliogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048709//oligodendrocyte differentiation;GO:0048546//digestive tract morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030318//melanocyte differentiation;GO:0048589//developmental growth;GO:0007422//peripheral nervous system development;GO:0048484//enteric nervous system development;GO:0009653//anatomical structure morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0002052//positive regulation of neuroblast proliferation;GO:0048469//cell maturation;GO:0001701//in utero embryonic development",GO:0003682//chromatin binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0005515//protein binding,-
6664,0,0,0,0,0,46,20,0,0,0,0,0,SOX11;SRY (sex determining region Y)-box 11,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0048485//sympathetic nervous system development;GO:0060563//neuroepithelial cell differentiation;GO:0021782//glial cell development;GO:0045669//positive regulation of osteoblast differentiation;GO:0048557//embryonic digestive tract morphogenesis;GO:0060174//limb bud formation;GO:0046887//positive regulation of hormone secretion;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0006412//translation;GO:0060253//negative regulation of glial cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001841//neural tube formation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003211//cardiac ventricle formation;GO:0014003//oligodendrocyte development;GO:0014032//neural crest cell development;GO:0030182//neuron differentiation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0045778//positive regulation of ossification;GO:0061053//somite development;GO:0014009//glial cell proliferation;GO:0035914//skeletal muscle cell differentiation;GO:0010629//negative regulation of gene expression;GO:0061029//eyelid development in camera-type eye;GO:0021510//spinal cord development;GO:0008284//positive regulation of cell proliferation;GO:0060425//lung morphogenesis;GO:0002089//lens morphogenesis in camera-type eye;GO:0001822//kidney development;GO:0061303//cornea development in camera-type eye;GO:0006351//transcription, DNA-templated;GO:2000648//positive regulation of stem cell proliferation;GO:0050672//negative regulation of lymphocyte proliferation;GO:0061386//closure of optic fissure;GO:0010628//positive regulation of gene expression;GO:0030513//positive regulation of BMP signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0060412//ventricular septum morphogenesis;GO:0003357//noradrenergic neuron differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0060022//hard palate development;GO:0050769//positive regulation of neurogenesis;GO:0001501//skeletal system development;GO:0072395//signal transduction involved in cell cycle checkpoint;GO:0048704//embryonic skeletal system morphogenesis;GO:0060023//soft palate development;GO:0060548//negative regulation of cell death","GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001071//nucleic acid binding transcription factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001158//enhancer sequence-specific DNA binding",-
6665,0,0,0,0,0,0,0,20,24,0,0,0,SOX15;SRY (sex determining region Y)-box 15,GO:0044798//nuclear transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0048627//myoblast development;GO:0070318//positive regulation of G0 to G1 transition;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0043403//skeletal muscle tissue regeneration;GO:0006325//chromatin organization;GO:0008584//male gonad development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045843//negative regulation of striated muscle tissue development;GO:2000288//positive regulation of myoblast proliferation;GO:0006366//transcription from RNA polymerase II promoter",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6666,192,0,0,0,19,11,0,33,29,49,7,0,SOX12;SRY (sex determining region Y)-box 12,GO:0032993//protein-DNA complex;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0065004//protein-DNA complex assembly;GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0021510//spinal cord development",GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003677//DNA binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
6667,148,137,1,58,298,0,0,1,58,0,8,0,SP1;Sp1 transcription factor,GO:0005730//nucleolus;GO:0032993//protein-DNA complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0016032//viral process;GO:0048706//embryonic skeletal system development;GO:0048511//rhythmic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060216//definitive hemopoiesis;GO:0001829//trophectodermal cell differentiation;GO:0048596//embryonic camera-type eye morphogenesis;GO:0001892//embryonic placenta development;GO:0030324//lung development;GO:0060136//embryonic process involved in female pregnancy;GO:0043923//positive regulation by host of viral transcription;GO:0001503//ossification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0043353//enucleate erythrocyte differentiation;GO:0044281//small molecule metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001889//liver development;GO:0030219//megakaryocyte differentiation;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression",GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008022//protein C-terminus binding;GO:0071837//HMG box domain binding;GO:0003677//DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0035326//enhancer binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003690//double-stranded DNA binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0035035//histone acetyltransferase binding,K04684//Transcriptional misregulation in cancer;TGF-beta signaling pathway;Huntington's disease
6668,0,0,0,0,10,8,29,0,4,1,7,0,SP2;Sp2 transcription factor,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0072358//cardiovascular system development;GO:0048144//fibroblast proliferation;GO:0006955//immune response;GO:0035264//multicellular organism growth;GO:0048568//embryonic organ development;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding,-
667,274,17,0,9,75,185,101,65,222,121,0,336,DST;dystonin,GO:0016021//integral component of membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0060053//neurofilament cytoskeleton;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005604//basement membrane;GO:0045111//intermediate filament cytoskeleton;GO:0031673//H zone;GO:0035371//microtubule plus-end;GO:0005789//endoplasmic reticulum membrane;GO:0005635//nuclear envelope;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0005882//intermediate filament;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0030056//hemidesmosome;GO:0005925//focal adhesion;GO:0030424//axon;GO:0015630//microtubule cytoskeleton;GO:0009925//basal plasma membrane;GO:0005634//nucleus,GO:0007155//cell adhesion;GO:0031122//cytoplasmic microtubule organization;GO:0000226//microtubule cytoskeleton organization;GO:0048870//cell motility;GO:0007010//cytoskeleton organization;GO:0030011//maintenance of cell polarity;GO:0008090//retrograde axon cargo transport;GO:0031110//regulation of microtubule polymerization or depolymerization;GO:0030198//extracellular matrix organization;GO:0031581//hemidesmosome assembly;GO:0007409//axonogenesis;GO:0007050//cell cycle arrest;GO:0007229//integrin-mediated signaling pathway;GO:0045104//intermediate filament cytoskeleton organization;GO:0009611//response to wounding,GO:0005515//protein binding;GO:0005178//integrin binding;GO:0042803//protein homodimerization activity;GO:0005509//calcium ion binding;GO:0051010//microtubule plus-end binding;GO:0008022//protein C-terminus binding;GO:0003779//actin binding,-
6670,17,59,0,52,107,53,14,8,49,0,0,0,SP3;Sp3 transcription factor,GO:0005634//nucleus;GO:0017053//transcriptional repressor complex;GO:0016605//PML body,"GO:0060136//embryonic process involved in female pregnancy;GO:0030224//monocyte differentiation;GO:0030324//lung development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030183//B cell differentiation;GO:0001779//natural killer cell differentiation;GO:0060216//definitive hemopoiesis;GO:0048706//embryonic skeletal system development;GO:0001829//trophectodermal cell differentiation;GO:0001892//embryonic placenta development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0006351//transcription, DNA-templated;GO:0030219//megakaryocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030851//granulocyte differentiation;GO:0001503//ossification;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043353//enucleate erythrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0001889//liver development;GO:0030217//T cell differentiation",GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003690//double-stranded DNA binding;GO:0000987//core promoter proximal region sequence-specific DNA binding,-
6671,0,0,0,9,21,0,21,0,39,0,0,0,SP4;Sp4 transcription factor,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,-
6672,127,13,0,16,90,2,30,0,71,195,1,0,SP100;SP100 nuclear antigen,GO:0030870//Mre11 complex;GO:0016605//PML body;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0034399//nuclear periphery;GO:0005737//cytoplasm,"GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0051271//negative regulation of cellular component movement;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0048384//retinoic acid receptor signaling pathway;GO:1902044//regulation of Fas signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032897//negative regulation of viral transcription;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000723//telomere maintenance;GO:0006351//transcription, DNA-templated;GO:0043392//negative regulation of DNA binding;GO:0045765//regulation of angiogenesis;GO:0060337//type I interferon signaling pathway;GO:0032526//response to retinoic acid;GO:0016032//viral process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0046826//negative regulation of protein export from nucleus;GO:0034341//response to interferon-gamma;GO:0010596//negative regulation of endothelial cell migration;GO:0019221//cytokine-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0034340//response to type I interferon;GO:0034097//response to cytokine;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity",GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0019900//kinase binding;GO:0070087//chromo shadow domain binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008134//transcription factor binding,K15413//Herpes simplex infection
6674,0,0,0,5,33,0,37,0,11,0,6,0,SPAG1;sperm associated antigen 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus,GO:0008152//metabolic process;GO:0007338//single fertilization;GO:0070286//axonemal dynein complex assembly,GO:0016787//hydrolase activity;GO:0005525//GTP binding,K09553//Prion diseases
6675,0,0,1,59,45,0,0,0,20,0,0,0,UAP1;UDP-N-acteylglucosamine pyrophosphorylase 1,GO:0005829//cytosol,GO:0043687//post-translational protein modification;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006048//UDP-N-acetylglucosamine biosynthetic process,GO:0030246//carbohydrate binding;GO:0003977//UDP-N-acetylglucosamine diphosphorylase activity,K00972//Metabolic pathways;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
6676,101,0,0,0,0,14,0,54,0,0,0,1,SPAG4;sperm associated antigen 4,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0031514//motile cilium,GO:0007283//spermatogenesis,GO:0005198//structural molecule activity,-
6677,0,0,2,0,0,8,0,1,38,0,0,0,"SPAM1;sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)",GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0007338//single fertilization;GO:0035036//sperm-egg recognition;GO:0007155//cell adhesion;GO:0032504//multicellular organism reproduction;GO:0005975//carbohydrate metabolic process;GO:0007342//fusion of sperm to egg plasma membrane;GO:0007339//binding of sperm to zona pellucida,GO:0004415//hyalurononglucosaminidase activity,"K01197//Glycosaminoglycan degradation;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Arginine and proline metabolism;Lysosome"
6678,83,0,0,0,0,44,7,0,19,0,5,0,"SPARC;secreted protein, acidic, cysteine-rich (osteonectin)",GO:0005739//mitochondrion;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0031091//platelet alpha granule;GO:0016363//nuclear matrix;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen;GO:0005737//cytoplasm;GO:0031092//platelet alpha granule membrane,GO:0007596//blood coagulation;GO:0034097//response to cytokine;GO:0030324//lung development;GO:0051592//response to calcium ion;GO:0043434//response to peptide hormone;GO:0002576//platelet degranulation;GO:0071363//cellular response to growth factor stimulus;GO:0060348//bone development;GO:0022604//regulation of cell morphogenesis;GO:0051591//response to cAMP;GO:0016525//negative regulation of angiogenesis;GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0048839//inner ear development;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032496//response to lipopolysaccharide;GO:0010595//positive regulation of endothelial cell migration;GO:0009629//response to gravity;GO:0046686//response to cadmium ion;GO:0010288//response to lead ion;GO:0045471//response to ethanol;GO:0001503//ossification;GO:0030198//extracellular matrix organization;GO:0051384//response to glucocorticoid;GO:0007507//heart development;GO:0033591//response to L-ascorbic acid,GO:0005518//collagen binding;GO:0050840//extracellular matrix binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
668,0,0,0,0,0,20,0,0,6,0,0,0,FOXL2;forkhead box L2,GO:0005634//nucleus,"GO:0002074//extraocular skeletal muscle development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030154//cell differentiation;GO:0060014//granulosa cell differentiation;GO:0006309//apoptotic DNA fragmentation;GO:0042703//menstruation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0019101//female somatic sex determination;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001541//ovarian follicle development;GO:0048048//embryonic eye morphogenesis",GO:0003677//DNA binding;GO:0030331//estrogen receptor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0043028//cysteine-type endopeptidase regulator activity involved in apoptotic process;GO:0031624//ubiquitin conjugating enzyme binding,-
6683,0,0,0,10,20,15,52,13,70,0,14,0,SPAST;spastin,GO:0030496//midbody;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0031410//cytoplasmic vesicle,"GO:0008219//cell death;GO:0051260//protein homooligomerization;GO:0007409//axonogenesis;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0034214//protein hexamerization;GO:0031117//positive regulation of microtubule depolymerization;GO:0051013//microtubule severing;GO:0006200//ATP catabolic process;GO:0001578//microtubule bundle formation;GO:0007109//cytokinesis, completion of separation",GO:0048487//beta-tubulin binding;GO:0008568//microtubule-severing ATPase activity;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0005524//ATP binding,-
6687,62,0,1,0,0,0,22,81,19,0,0,0,SPG7;spastic paraplegia 7 (pure and complicated autosomal recessive),GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane,GO:0008219//cell death;GO:0007399//nervous system development;GO:0008089//anterograde axon cargo transport;GO:0007005//mitochondrion organization;GO:0006508//proteolysis,GO:0005524//ATP binding;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0051082//unfolded protein binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
6689,0,0,0,0,0,31,18,0,0,0,0,1,SPIB;Spi-B transcription factor (Spi-1/PU.1 related),GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006366//transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0043565//sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,K02327//Nucleotide excision repair;HTLV-I infection;Mismatch repair;Pyrimidine metabolism;Base excision repair;Homologous recombination;Metabolic pathways;DNA replication;Purine metabolism
669,0,0,0,24,35,0,0,3,11,44,0,0,"BPGM;2,3-bisphosphoglycerate mutase",GO:0070062//extracellular vesicular exosome,GO:0005975//carbohydrate metabolic process;GO:0016311//dephosphorylation;GO:0007585//respiratory gaseous exchange;GO:0006096//glycolytic process;GO:0048821//erythrocyte development,GO:0004082//bisphosphoglycerate mutase activity;GO:0004619//phosphoglycerate mutase activity;GO:0004083//bisphosphoglycerate 2-phosphatase activity,"K01837//Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism"
6690,0,0,0,8,10,0,0,0,0,0,0,0,"SPINK1;serine peptidase inhibitor, Kazal type 1",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0050732//negative regulation of peptidyl-tyrosine phosphorylation;GO:2001256//regulation of store-operated calcium entry;GO:0060046//regulation of acrosome reaction;GO:0090281//negative regulation of calcium ion import;GO:1900004//negative regulation of serine-type endopeptidase activity;GO:0010751//negative regulation of nitric oxide mediated signal transduction,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding,K06254//ECM-receptor interaction
6691,0,0,0,0,0,13,0,0,2,0,0,0,"SPINK2;serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K06254//ECM-receptor interaction
6692,1,373,85,183,584,0,0,205,41,1,809,0,"SPINT1;serine peptidase inhibitor, Kunitz type 1",GO:0016020//membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0060674//placenta blood vessel development;GO:0010951//negative regulation of endopeptidase activity;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0030198//extracellular matrix organization,GO:0004867//serine-type endopeptidase inhibitor activity,K15619//Transcriptional misregulation in cancer
6693,65,25,0,8,3,11,0,1,11,0,30,0,SPN;sialophorin,GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane;GO:0001931//uropod,GO:0042130//negative regulation of T cell proliferation;GO:0006935//chemotaxis;GO:0006968//cellular defense response;GO:0007596//blood coagulation;GO:0007162//negative regulation of cell adhesion;GO:0007166//cell surface receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0042102//positive regulation of T cell proliferation;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0050688//regulation of defense response to virus;GO:0006955//immune response;GO:0001562//response to protozoan;GO:0042742//defense response to bacterium;GO:0007163//establishment or maintenance of cell polarity;GO:0045060//negative thymic T cell selection;GO:0031295//T cell costimulation;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0001808//negative regulation of type IV hypersensitivity,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K06477//Epstein-Barr virus infection;Cell adhesion molecules (CAMs)
6695,0,54,0,24,63,0,53,0,65,0,0,0,"SPOCK1;sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1",GO:0033268//node of Ranvier;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0014069//postsynaptic density;GO:0031594//neuromuscular junction;GO:0016528//sarcoplasm;GO:0005615//extracellular space,GO:0007399//nervous system development;GO:0010812//negative regulation of cell-substrate adhesion;GO:0007155//cell adhesion;GO:0021953//central nervous system neuron differentiation;GO:0010951//negative regulation of endopeptidase activity;GO:0001764//neuron migration;GO:0007165//signal transduction;GO:0010977//negative regulation of neuron projection development;GO:0001558//regulation of cell growth;GO:0022008//neurogenesis,GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0005509//calcium ion binding;GO:0004867//serine-type endopeptidase inhibitor activity,-
6696,0,0,0,0,0,0,0,52,22,0,0,0,SPP1;secreted phosphoprotein 1,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0042995//cell projection;GO:0045177//apical part of cell,GO:0030198//extracellular matrix organization;GO:0001649//osteoblast differentiation;GO:0006954//inflammatory response;GO:0033280//response to vitamin D;GO:0022617//extracellular matrix disassembly;GO:0031214//biomineral tissue development;GO:0030593//neutrophil chemotaxis;GO:0045780//positive regulation of bone resorption;GO:0046697//decidualization;GO:0007566//embryo implantation;GO:0007155//cell adhesion;GO:0010811//positive regulation of cell-substrate adhesion;GO:0048685//negative regulation of collateral sprouting of intact axon in response to injury;GO:0048545//response to steroid hormone,GO:0050840//extracellular matrix binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K06250//ECM-receptor interaction;Toll-like receptor signaling pathway;Focal adhesion
6697,0,25,0,7,46,0,0,73,25,0,9,0,"SPR;sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0044281//small molecule metabolic process;GO:0042428//serotonin metabolic process;GO:0048667//cell morphogenesis involved in neuron differentiation;GO:0040014//regulation of multicellular organism growth;GO:0016265//death;GO:0042415//norepinephrine metabolic process;GO:0050882//voluntary musculoskeletal movement;GO:0046209//nitric oxide metabolic process;GO:0019889//pteridine metabolic process;GO:0006558//L-phenylalanine metabolic process;GO:0042417//dopamine metabolic process;GO:0006729//tetrahydrobiopterin biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006809//nitric oxide biosynthetic process;GO:0050999//regulation of nitric-oxide synthase activity,GO:0050661//NADP binding;GO:0004757//sepiapterin reductase activity;GO:0004033//aldo-keto reductase (NADP) activity,K00072//Folate biosynthesis;Metabolic pathways
6698,0,0,0,0,0,0,0,0,0,139,0,0,SPRR1A;small proline-rich protein 1A,GO:0005737//cytoplasm;GO:0001533//cornified envelope,GO:0030216//keratinocyte differentiation;GO:0008544//epidermis development;GO:0018149//peptide cross-linking;GO:0031424//keratinization,"GO:0005515//protein binding;GO:0030674//protein binding, bridging;GO:0005198//structural molecule activity",-
6699,0,0,0,0,0,0,0,0,34,0,0,0,SPRR1B;small proline-rich protein 1B,GO:0001533//cornified envelope;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0031424//keratinization;GO:0018149//peptide cross-linking;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation,"GO:0005198//structural molecule activity;GO:0030674//protein binding, bridging",-
670,0,0,1,0,1,0,0,3,4,0,5,0,BPHL;biphenyl hydrolase-like (serine hydrolase),GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0006520//cellular amino acid metabolic process;GO:0009636//response to toxic substance,GO:0016787//hydrolase activity,K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
6701,0,0,0,0,0,5,0,0,14,0,0,0,SPRR2B;small proline-rich protein 2B,GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation,-,-
6703,0,0,0,0,0,0,3,0,0,0,0,0,SPRR2D;small proline-rich protein 2D,GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0008544//epidermis development,-,-
6704,3,0,0,0,0,0,0,0,0,0,0,0,SPRR2E;small proline-rich protein 2E,GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0008544//epidermis development;GO:0031424//keratinization,GO:0005515//protein binding;GO:0005198//structural molecule activity,-
6705,0,0,0,0,0,0,0,0,0,0,9,0,SPRR2F;small proline-rich protein 2F,GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation,-,-
6706,0,0,0,0,0,0,0,0,12,0,0,0,SPRR2G;small proline-rich protein 2G,GO:0001533//cornified envelope;GO:0005737//cytoplasm,GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0031424//keratinization,-,-
6707,0,0,0,0,0,18,0,0,24,0,0,81,SPRR3;small proline-rich protein 3,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0031424//keratinization;GO:0042060//wound healing;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0018149//peptide cross-linking,GO:0005198//structural molecule activity;GO:0005515//protein binding,K06261//ECM-receptor interaction;Hematopoietic cell lineage
6708,0,0,0,0,0,18,59,57,115,0,26,0,"SPTA1;spectrin, alpha, erythrocytic 1",GO:0008091//spectrin;GO:0032437//cuticular plate;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0014731//spectrin-associated cytoskeleton;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane,GO:0007411//axon guidance;GO:0006779//porphyrin-containing compound biosynthetic process;GO:0002260//lymphocyte homeostasis;GO:0007015//actin filament organization;GO:0008360//regulation of cell shape;GO:0032092//positive regulation of protein binding;GO:0030097//hemopoiesis;GO:0007009//plasma membrane organization;GO:0051693//actin filament capping;GO:0042102//positive regulation of T cell proliferation,GO:0005200//structural constituent of cytoskeleton;GO:0051015//actin filament binding;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K06114//Tight junction
6709,0,23,0,80,62,22,162,59,72,402,171,0,"SPTAN1;spectrin, alpha, non-erythrocytic 1",GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0015630//microtubule cytoskeleton;GO:0005916//fascia adherens;GO:0016020//membrane;GO:0008091//spectrin;GO:0032437//cuticular plate;GO:0070062//extracellular vesicular exosome;GO:0016328//lateral plasma membrane;GO:0030018//Z disc;GO:0031982//vesicle,GO:0006915//apoptotic process;GO:0051693//actin filament capping;GO:0007411//axon guidance;GO:0006921//cellular component disassembly involved in execution phase of apoptosis,GO:0005200//structural constituent of cytoskeleton;GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0030507//spectrin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K06114//Tight junction
671,0,0,2,0,0,10,31,0,45,0,0,0,BPI;bactericidal/permeability-increasing protein,GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0032717//negative regulation of interleukin-8 production;GO:0043031//negative regulation of macrophage activation;GO:0042742//defense response to bacterium;GO:0032720//negative regulation of tumor necrosis factor production;GO:0006955//immune response;GO:0032715//negative regulation of interleukin-6 production,GO:0001530//lipopolysaccharide binding,K05399//Salmonella infection;NF-kappa B signaling pathway;Tuberculosis;Toll-like receptor signaling pathway
6710,81,43,0,20,13,13,101,0,90,1,49,0,"SPTB;spectrin, beta, erythrocytic",GO:0014731//spectrin-associated cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0008091//spectrin;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0043234//protein complex,GO:0006779//porphyrin-containing compound biosynthetic process;GO:0007411//axon guidance;GO:0051693//actin filament capping;GO:0030097//hemopoiesis;GO:0007009//plasma membrane organization,GO:0051015//actin filament binding;GO:0005515//protein binding;GO:0030506//ankyrin binding;GO:0046982//protein heterodimerization activity;GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding,K06115//Tight junction
6711,17,48,1,31,71,11,32,0,79,0,7,0,"SPTBN1;spectrin, beta, non-erythrocytic 1",GO:0031430//M band;GO:0005730//nucleolus;GO:0030673//axolemma;GO:0014731//spectrin-associated cytoskeleton;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome;GO:0008091//spectrin,GO:0007009//plasma membrane organization;GO:0000281//mitotic cytokinesis;GO:0051693//actin filament capping;GO:0043001//Golgi to plasma membrane protein transport;GO:0072661//protein targeting to plasma membrane;GO:0071709//membrane assembly;GO:0007411//axon guidance,GO:0003779//actin binding;GO:0032403//protein complex binding;GO:0005200//structural constituent of cytoskeleton;GO:0005516//calmodulin binding;GO:0030506//ankyrin binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005543//phospholipid binding,K06115//Tight junction
6712,71,41,15,9,12,28,33,0,78,46,11,0,"SPTBN2;spectrin, beta, non-erythrocytic 2",GO:0008091//spectrin;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane,GO:0051693//actin filament capping;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0035264//multicellular organism growth;GO:0030534//adult behavior;GO:0007411//axon guidance;GO:0008219//cell death;GO:0007416//synapse assembly;GO:0021692//cerebellar Purkinje cell layer morphogenesis;GO:0016192//vesicle-mediated transport,GO:0005200//structural constituent of cytoskeleton;GO:0003779//actin binding;GO:0005543//phospholipid binding,K06115//Tight junction
6713,0,0,0,0,17,13,23,39,46,0,0,0,SQLE;squalene epoxidase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0006695//cholesterol biosynthetic process;GO:0010033//response to organic substance;GO:0006725//cellular aromatic compound metabolic process;GO:0044281//small molecule metabolic process;GO:0016126//sterol biosynthetic process,GO:0004506//squalene monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding,K00511//Biosynthesis of secondary metabolites;Metabolic pathways;Sesquiterpenoid and triterpenoid biosynthesis
6714,0,26,0,6,10,20,27,1,2,0,16,265,"SRC;SRC proto-oncogene, non-receptor tyrosine kinase",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005901//caveola;GO:0005764//lysosome,GO:0048477//oogenesis;GO:0007411//axon guidance;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0030900//forebrain development;GO:0033625//positive regulation of integrin activation;GO:0051902//negative regulation of mitochondrial depolarization;GO:0051895//negative regulation of focal adhesion assembly;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0007172//signal complex assembly;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0060065//uterus development;GO:0061024//membrane organization;GO:0032463//negative regulation of protein homooligomerization;GO:0045453//bone resorption;GO:0033146//regulation of intracellular estrogen receptor signaling pathway;GO:0071393//cellular response to progesterone stimulus;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0046777//protein autophosphorylation;GO:0022407//regulation of cell-cell adhesion;GO:2000641//regulation of early endosome to late endosome transport;GO:0043393//regulation of protein binding;GO:0070555//response to interleukin-1;GO:0043066//negative regulation of apoptotic process;GO:0035556//intracellular signal transduction;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0043114//regulation of vascular permeability;GO:2000811//negative regulation of anoikis;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0007049//cell cycle;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050847//progesterone receptor signaling pathway;GO:0051897//positive regulation of protein kinase B signaling;GO:0045087//innate immune response;GO:0007155//cell adhesion;GO:0007596//blood coagulation;GO:0043149//stress fiber assembly;GO:0030168//platelet activation;GO:0071803//positive regulation of podosome assembly;GO:0045124//regulation of bone resorption;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016032//viral process,GO:0046875//ephrin receptor binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0042169//SH2 domain binding;GO:0005102//receptor binding;GO:0051219//phosphoprotein binding;GO:0044325//ion channel binding;GO:0020037//heme binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0016301//kinase activity;GO:0005070//SH3/SH2 adaptor activity;GO:0070851//growth factor receptor binding;GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005178//integrin binding;GO:0005515//protein binding,K05704//Tuberculosis;Shigellosis;GnRH signaling pathway;Chemokine signaling pathway;Tight junction;GABAergic synapse;Gap junction;Bacterial invasion of epithelial cells;Endocytosis;Adherens junction;ErbB signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Focal adhesion;VEGF signaling pathway;Regulation of actin cytoskeleton
6715,0,1,0,3,28,0,0,0,10,0,14,0,"SRD5A1;steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0007530//sex determination;GO:0007548//sex differentiation;GO:0006702//androgen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0030154//cell differentiation;GO:0008202//steroid metabolic process,GO:0047751//cholestenone 5-alpha-reductase activity;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0009055//electron carrier activity,K12343//Steroid hormone biosynthesis
6716,0,0,0,0,0,0,0,0,13,0,0,0,"SRD5A2;steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0008202//steroid metabolic process;GO:0055114//oxidation-reduction process;GO:0008209//androgen metabolic process;GO:0008584//male gonad development;GO:0007267//cell-cell signaling;GO:0030154//cell differentiation;GO:0044281//small molecule metabolic process;GO:0006702//androgen biosynthetic process,GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0047751//cholestenone 5-alpha-reductase activity;GO:0009917//sterol 5-alpha reductase activity,K12344//Prostate cancer;Steroid hormone biosynthesis
6717,0,0,1,47,60,0,6,0,1,0,0,0,SRI;sorcin,GO:0005829//cytosol;GO:0016529//sarcoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0030315//T-tubule;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0030018//Z disc;GO:0042584//chromaffin granule membrane;GO:0005737//cytoplasm,GO:0051924//regulation of calcium ion transport;GO:0006508//proteolysis;GO:0006942//regulation of striated muscle contraction;GO:0007517//muscle organ development;GO:0006810//transport;GO:0007165//signal transduction;GO:0006816//calcium ion transport;GO:0010649//regulation of cell communication by electrical coupling;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0006880//intracellular sequestering of iron ion;GO:0086004//regulation of cardiac muscle cell contraction;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0008016//regulation of heart contraction;GO:1901077//regulation of relaxation of muscle;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0007507//heart development;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0001508//action potential;GO:0010459//negative regulation of heart rate;GO:1901841//regulation of high voltage-gated calcium channel activity,GO:0005102//receptor binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0002020//protease binding;GO:0046982//protein heterodimerization activity;GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0005246//calcium channel regulator activity;GO:0070491//repressing transcription factor binding,K07359//Adipocytokine signaling pathway;Alcoholism
6718,0,0,0,0,0,0,0,0,7,0,0,0,"AKR1D1;aldo-keto reductase family 1, member D1",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0008207//C21-steroid hormone metabolic process;GO:0055114//oxidation-reduction process;GO:0008206//bile acid metabolic process;GO:0008209//androgen metabolic process;GO:0006699//bile acid biosynthetic process;GO:0007586//digestion;GO:0030573//bile acid catabolic process;GO:0044281//small molecule metabolic process;GO:0006707//cholesterol catabolic process,GO:0047787//delta4-3-oxosteroid 5beta-reductase activity;GO:0005496//steroid binding,K00251//Steroid hormone biosynthesis;Primary bile acid biosynthesis;Metabolic pathways
6719,0,0,0,0,0,0,0,0,7,71,0,0,"SRD5A1P1;steroid-5-alpha-reductase, alpha polypeptide 1 pseudogene 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha pseudogene)",-,-,-,K12343//Steroid hormone biosynthesis
672,0,0,0,0,0,42,105,0,75,4,11,7,"BRCA1;breast cancer 1, early onset",GO:0005694//chromosome;GO:0070531//BRCA1-A complex;GO:0005886//plasma membrane;GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0008274//gamma-tubulin ring complex;GO:0031436//BRCA1-BARD1 complex;GO:0005634//nucleus,"GO:0006281//DNA repair;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0006302//double-strand break repair;GO:0006633//fatty acid biosynthetic process;GO:0042981//regulation of apoptotic process;GO:2000620//positive regulation of histone H4-K16 acetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043627//response to estrogen;GO:0051573//negative regulation of histone H3-K9 methylation;GO:0000724//double-strand break repair via homologous recombination;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006301//postreplication repair;GO:0006915//apoptotic process;GO:0046600//negative regulation of centriole replication;GO:0010212//response to ionizing radiation;GO:0070512//positive regulation of histone H4-K20 methylation;GO:0045717//negative regulation of fatty acid biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045766//positive regulation of angiogenesis;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0016567//protein ubiquitination;GO:0045739//positive regulation of DNA repair;GO:0031398//positive regulation of protein ubiquitination;GO:0071356//cellular response to tumor necrosis factor;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007059//chromosome segregation;GO:0085020//protein K6-linked ubiquitination;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0031572//G2 DNA damage checkpoint;GO:0071158//positive regulation of cell cycle arrest;GO:0051865//protein autoubiquitination;GO:0071681//cellular response to indole-3-methanol;GO:2000617//positive regulation of histone H3-K9 acetylation;GO:0010628//positive regulation of gene expression;GO:0035066//positive regulation of histone acetylation",GO:0003677//DNA binding;GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0050681//androgen receptor binding;GO:0003713//transcription coactivator activity;GO:0003723//RNA binding;GO:0019899//enzyme binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0015631//tubulin binding;GO:0044212//transcription regulatory region DNA binding,K10605//Ubiquitin mediated proteolysis;Fanconi anemia pathway
6720,0,1,0,0,8,32,23,36,48,91,6,0,SREBF1;sterol regulatory element binding transcription factor 1,GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005829//cytosol,"GO:0030324//lung development;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0007623//circadian rhythm;GO:0008286//insulin receptor signaling pathway;GO:0046676//negative regulation of insulin secretion;GO:0071398//cellular response to fatty acid;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051591//response to cAMP;GO:0007568//aging;GO:0032526//response to retinoic acid;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0032570//response to progesterone;GO:0009267//cellular response to starvation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0031065//positive regulation of histone deacetylation;GO:0006351//transcription, DNA-templated;GO:0032094//response to food;GO:0003062//regulation of heart rate by chemical signal;GO:0033762//response to glucagon;GO:0008203//cholesterol metabolic process;GO:0019217//regulation of fatty acid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0009749//response to glucose;GO:0006629//lipid metabolic process;GO:0042493//response to drug;GO:0008610//lipid biosynthetic process;GO:0044281//small molecule metabolic process",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0032810//sterol response element binding;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding;GO:0032403//protein complex binding,K07197//Insulin signaling pathway
6721,0,0,0,1,35,15,19,1,58,1,0,286,SREBF2;sterol regulatory element binding transcription factor 2,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0012507//ER to Golgi transport vesicle membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0032937//SREBP-SCAP-Insig complex;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:2000188//regulation of cholesterol homeostasis;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010886//positive regulation of cholesterol storage;GO:0006629//lipid metabolic process;GO:0071499//cellular response to laminar fluid shear stress;GO:0072368//regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter;GO:0008203//cholesterol metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0055098//response to low-density lipoprotein particle;GO:0006351//transcription, DNA-templated;GO:0090370//negative regulation of cholesterol efflux",GO:0000247//C-8 sterol isomerase activity;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0008022//protein C-terminus binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0070888//E-box binding,-
6722,1,43,0,19,0,0,0,65,35,0,14,0,SRF;serum response factor (c-fos serum response element-binding transcription factor),GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007616//long-term memory;GO:0009725//response to hormone;GO:0070830//tight junction assembly;GO:0001829//trophectodermal cell differentiation;GO:0046016//positive regulation of transcription by glucose;GO:0046716//muscle cell cellular homeostasis;GO:0045214//sarcomere organization;GO:0001666//response to hypoxia;GO:0034097//response to cytokine;GO:0043589//skin morphogenesis;GO:0045597//positive regulation of cell differentiation;GO:0007160//cell-matrix adhesion;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0045987//positive regulation of smooth muscle contraction;GO:0090398//cellular senescence;GO:0090009//primitive streak formation;GO:0001707//mesoderm formation;GO:0045059//positive thymic T cell selection;GO:0048821//erythrocyte development;GO:0033561//regulation of water loss via skin;GO:0055003//cardiac myofibril assembly;GO:0031175//neuron projection development;GO:0001947//heart looping;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0060347//heart trabecula formation;GO:0030038//contractile actin filament bundle assembly;GO:0035855//megakaryocyte development;GO:0042789//mRNA transcription from RNA polymerase II promoter;GO:0051150//regulation of smooth muscle cell differentiation;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0035912//dorsal aorta morphogenesis;GO:0051491//positive regulation of filopodium assembly;GO:0030220//platelet formation;GO:0060218//hematopoietic stem cell differentiation;GO:0030168//platelet activation;GO:0001569//patterning of blood vessels;GO:0048589//developmental growth;GO:0043149//stress fiber assembly;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030155//regulation of cell adhesion;GO:0001764//neuron migration;GO:0060947//cardiac vascular smooth muscle cell differentiation;GO:0060292//long term synaptic depression;GO:0071333//cellular response to glucose stimulus;GO:0010669//epithelial structure maintenance;GO:0022028//tangential migration from the subventricular zone to the olfactory bulb;GO:0060055//angiogenesis involved in wound healing;GO:0061029//eyelid development in camera-type eye;GO:0048666//neuron development;GO:0090136//epithelial cell-cell adhesion;GO:0009636//response to toxic substance;GO:0021766//hippocampus development;GO:0007507//heart development;GO:0010735//positive regulation of transcription via serum response element binding;GO:1900222//negative regulation of beta-amyloid clearance;GO:0008285//negative regulation of cell proliferation;GO:0002011//morphogenesis of an epithelial sheet;GO:0008306//associative learning;GO:0030336//negative regulation of cell migration,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0031490//chromatin DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0010736//serum response element binding;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity,K04378//MAPK signaling pathway;HTLV-I infection
6723,0,0,0,0,14,0,0,0,8,0,20,0,SRM;spermidine synthase,GO:0005829//cytosol,GO:0008295//spermidine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0004766//spermidine synthase activity;GO:0042803//protein homodimerization activity,K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
6725,47,2,0,21,98,24,58,565,25,0,132,0,SRMS;src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites,GO:0005737//cytoplasm,GO:0038083//peptidyl-tyrosine autophosphorylation,GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,-
6726,0,114,5,248,622,2,1,0,17,0,24,0,SRP9;signal recognition particle 9kDa,"GO:0005829//cytosol;GO:0005785//signal recognition particle receptor complex;GO:0070062//extracellular vesicular exosome;GO:0005786//signal recognition particle, endoplasmic reticulum targeting",GO:0010467//gene expression;GO:0045900//negative regulation of translational elongation;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation,GO:0008312//7S RNA binding;GO:0005047//signal recognition particle binding;GO:0003723//RNA binding,K03109//Protein export
6727,149,17,5,23,84,14,0,0,0,0,1,0,SRP14;signal recognition particle 14kDa (homologous Alu RNA binding protein),"GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0045171//intercellular bridge;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm",GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006613//cotranslational protein targeting to membrane;GO:0042493//response to drug;GO:0006412//translation,GO:0008312//7S RNA binding;GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0030942//endoplasmic reticulum signal peptide binding,K03104//Protein export
6728,0,18,1,12,46,0,0,0,25,0,0,0,SRP19;signal recognition particle 19kDa,"GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005829//cytosol;GO:0005739//mitochondrion",GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006613//cotranslational protein targeting to membrane;GO:0042493//response to drug;GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0008312//7S RNA binding,K03105//Protein export
6729,0,0,0,17,200,10,0,0,15,0,0,0,SRP54;signal recognition particle 54kDa,"GO:0005829//cytosol;GO:0016607//nuclear speck;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm","GO:0006616//SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0042493//response to drug;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0006184//GTP catabolic process;GO:0006617//SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition",GO:0043021//ribonucleoprotein complex binding;GO:0044822//poly(A) RNA binding;GO:0008312//7S RNA binding;GO:0003924//GTPase activity;GO:0030942//endoplasmic reticulum signal peptide binding;GO:0019003//GDP binding;GO:0008144//drug binding;GO:0005525//GTP binding,K03106//Pyruvate metabolism;Metabolic pathways;Purine metabolism;Bacterial secretion system;Biosynthesis of secondary metabolites;Protein export
673,0,25,1,38,117,0,3,2,9,0,0,0,"BRAF;B-Raf proto-oncogene, serine/threonine kinase",GO:0005634//nucleus;GO:0044297//cell body;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005739//mitochondrion,"GO:0043434//response to peptide hormone;GO:0051291//protein heterooligomerization;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0010764//negative regulation of fibroblast migration;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0060291//long-term synaptic potentiation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0043368//positive T cell selection;GO:0035019//somatic stem cell maintenance;GO:0043524//negative regulation of neuron apoptotic process;GO:0002318//myeloid progenitor cell differentiation;GO:0051496//positive regulation of stress fiber assembly;GO:0042127//regulation of cell proliferation;GO:2000301//negative regulation of synaptic vesicle exocytosis;GO:0008542//visual learning;GO:0051591//response to cAMP;GO:0009887//organ morphogenesis;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0000186//activation of MAPKK activity;GO:0035690//cellular response to drug;GO:0000165//MAPK cascade;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0071277//cellular response to calcium ion;GO:0007264//small GTPase mediated signal transduction;GO:0070849//response to epidermal growth factor;GO:0048011//neurotrophin TRK receptor signaling pathway",GO:0031434//mitogen-activated protein kinase kinase binding;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005509//calcium ion binding;GO:0046982//protein heterodimerization activity;GO:0031267//small GTPase binding;GO:0005515//protein binding;GO:0004709//MAP kinase kinase kinase activity,K04365//Bladder cancer;ErbB signaling pathway;Colorectal cancer;Renal cell carcinoma;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Vascular smooth muscle contraction;mTOR signaling pathway;Chronic myeloid leukemia;Prostate cancer;Serotonergic synapse;Alcoholism;Progesterone-mediated oocyte maturation;Long-term potentiation;Chemokine signaling pathway;Pathways in cancer;Insulin signaling pathway;Pancreatic cancer;Glioma;Thyroid cancer;Focal adhesion;Non-small cell lung cancer;Endometrial cancer;Melanoma;Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;Acute myeloid leukemia;Long-term depression
6730,0,0,0,21,31,0,16,48,0,0,0,72,SRP68;signal recognition particle 68kDa,"GO:0005730//nucleolus;GO:0005786//signal recognition particle, endoplasmic reticulum targeting;GO:0005840//ribosome;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol",GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006412//translation;GO:0042493//response to drug;GO:0006614//SRP-dependent cotranslational protein targeting to membrane,GO:0030942//endoplasmic reticulum signal peptide binding;GO:0044822//poly(A) RNA binding;GO:0008312//7S RNA binding;GO:0005047//signal recognition particle binding,K03107//Protein export
6731,74,46,1,39,152,10,53,0,71,0,24,0,SRP72;signal recognition particle 72kDa,"GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005786//signal recognition particle, endoplasmic reticulum targeting",GO:0006412//translation;GO:0042493//response to drug;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,GO:0008312//7S RNA binding;GO:0005047//signal recognition particle binding;GO:0044822//poly(A) RNA binding,K03108//Protein export
6732,0,0,0,20,29,11,41,43,59,0,0,0,SRPK1;SRSF protein kinase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum,"GO:0035092//sperm chromatin condensation;GO:0045070//positive regulation of viral genome replication;GO:0045087//innate immune response;GO:0016032//viral process;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0050684//regulation of mRNA processing;GO:0045071//negative regulation of viral genome replication;GO:0008380//RNA splicing;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0006397//mRNA processing;GO:0035556//intracellular signal transduction",GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K15409//Herpes simplex infection
6733,86,28,1,7,44,0,125,8,30,0,0,0,SRPK2;SRSF protein kinase 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0000245//spliceosomal complex assembly;GO:0043525//positive regulation of neuron apoptotic process;GO:0045071//negative regulation of viral genome replication;GO:0035556//intracellular signal transduction;GO:0006468//protein phosphorylation;GO:0035063//nuclear speck organization;GO:0010628//positive regulation of gene expression;GO:0008380//RNA splicing;GO:0045087//innate immune response;GO:0030154//cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0045787//positive regulation of cell cycle;GO:0045070//positive regulation of viral genome replication;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0001525//angiogenesis",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0071889//14-3-3 protein binding;GO:0005524//ATP binding,-
6734,0,0,1,42,10,0,103,33,31,1,5,0,SRPR;signal recognition particle receptor (docking protein),GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005785//signal recognition particle receptor complex;GO:0005783//endoplasmic reticulum,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006613//cotranslational protein targeting to membrane;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006184//GTP catabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0044822//poly(A) RNA binding;GO:0005525//GTP binding;GO:0005047//signal recognition particle binding;GO:0003924//GTPase activity,K13431//Protein export
6737,0,1,0,10,39,20,0,122,32,0,2,0,TRIM21;tripartite motif containing 21,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0019005//SCF ubiquitin ligase complex,GO:0007049//cell cycle;GO:0051865//protein autoubiquitination;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:1902187//negative regulation of viral release from host cell;GO:0032897//negative regulation of viral transcription;GO:0016567//protein ubiquitination;GO:0006513//protein monoubiquitination;GO:0000209//protein polyubiquitination;GO:0090086//negative regulation of protein deubiquitination;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045787//positive regulation of cell cycle;GO:0070206//protein trimerization;GO:0031648//protein destabilization;GO:0046598//positive regulation of viral entry into host cell;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity,GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10651//Systemic lupus erythematosus
6738,0,164,120,180,310,0,0,9,19,0,4,66,"TROVE2;TROVE domain family, member 2",GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0060271//cilium morphogenesis;GO:0009411//response to UV;GO:0006383//transcription from RNA polymerase III promoter;GO:0007224//smoothened signaling pathway;GO:0002520//immune system development,GO:0030620//U2 snRNA binding;GO:0046872//metal ion binding;GO:0003723//RNA binding,K11089//Systemic lupus erythematosus
6741,0,34,34,72,164,17,6,27,0,0,41,0,SSB;Sjogren syndrome antigen B (autoantigen La),GO:0030529//ribonucleoprotein complex;GO:0005634//nucleus,GO:0008334//histone mRNA metabolic process;GO:0006400//tRNA modification,GO:0000049//tRNA binding;GO:0003729//mRNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11090//Systemic lupus erythematosus
6742,0,1,0,1,38,23,0,0,2,0,4,0,"SSBP1;single-stranded DNA binding protein 1, mitochondrial",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion,GO:0070584//mitochondrion morphogenesis;GO:0051096//positive regulation of helicase activity;GO:0006260//DNA replication,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003697//single-stranded DNA binding;GO:0003682//chromatin binding,K03111//Mismatch repair;Homologous recombination;Biosynthesis of secondary metabolites;Polyketide sugar unit biosynthesis;Metabolic pathways;Streptomycin biosynthesis;DNA replication
6744,11,0,1,21,69,17,0,1,25,0,0,0,SSFA2;sperm specific antigen 2,GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0003779//actin binding;GO:0005102//receptor binding,-
6745,0,25,0,18,54,13,42,51,8,0,19,0,"SSR1;signal sequence receptor, alpha",GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006613//cotranslational protein targeting to membrane;GO:0008284//positive regulation of cell proliferation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0005515//protein binding,K13249//Protein processing in endoplasmic reticulum
6746,0,0,2,0,4,0,0,1,45,0,0,0,"SSR2;signal sequence receptor, beta (translocon-associated protein beta)",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006613//cotranslational protein targeting to membrane;GO:0006412//translation,-,K13250//Protein processing in endoplasmic reticulum
6747,221,10,0,46,107,3,0,0,17,0,0,0,"SSR3;signal sequence receptor, gamma (translocon-associated protein gamma)",GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005784//Sec61 translocon complex,GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane,-,K13251//Protein processing in endoplasmic reticulum
6748,0,163,190,44,124,27,0,157,0,44,93,0,"SSR4;signal sequence receptor, delta",GO:0005784//Sec61 translocon complex;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process,-,K04571//Protein processing in endoplasmic reticulum
6749,0,42,0,25,163,23,39,0,17,0,0,0,SSRP1;structure specific recognition protein 1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005694//chromosome;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0006260//DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
675,73,0,0,0,0,17,14,0,58,0,0,0,"BRCA2;breast cancer 2, early onset",GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030141//secretory granule;GO:0033593//BRCA2-MAGE-D1 complex;GO:0005730//nucleolus,"GO:0007283//spermatogenesis;GO:0000724//double-strand break repair via homologous recombination;GO:0033600//negative regulation of mammary gland epithelial cell proliferation;GO:0006289//nucleotide-excision repair;GO:0030097//hemopoiesis;GO:0007569//cell aging;GO:0010165//response to X-ray;GO:0032465//regulation of cytokinesis;GO:0006281//DNA repair;GO:0043966//histone H3 acetylation;GO:0006302//double-strand break repair;GO:0043967//histone H4 acetylation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0000910//cytokinesis;GO:0051298//centrosome duplication;GO:0007420//brain development;GO:0010225//response to UV-C;GO:0048478//replication fork protection;GO:0001556//oocyte maturation;GO:0008585//female gonad development;GO:0001833//inner cell mass cell proliferation;GO:0010332//response to gamma radiation;GO:0007141//male meiosis I;GO:0045931//positive regulation of mitotic cell cycle;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0045893//positive regulation of transcription, DNA-templated",GO:0002020//protease binding;GO:0043015//gamma-tubulin binding;GO:0010484//H3 histone acetyltransferase activity;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding;GO:0010485//H4 histone acetyltransferase activity;GO:0004402//histone acetyltransferase activity,K08775//Homologous recombination;Fanconi anemia pathway;Pathways in cancer;Pancreatic cancer
6750,0,0,0,0,0,0,0,0,0,0,15,0,SST;somatostatin,GO:0043025//neuronal cell body;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0009408//response to heat;GO:0007166//cell surface receptor signaling pathway;GO:0007584//response to nutrient;GO:0006972//hyperosmotic response;GO:0043200//response to amino acid;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007268//synaptic transmission;GO:0048545//response to steroid hormone;GO:0007267//cell-cell signaling;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0042493//response to drug;GO:0007586//digestion;GO:0030334//regulation of cell migration,GO:0005179//hormone activity,K05237//Gastric acid secretion
6751,0,2,0,10,0,0,0,18,3,0,0,0,SSTR1;somatostatin receptor 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0007586//digestion;GO:0021549//cerebellum development;GO:0007267//cell-cell signaling;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0007584//response to nutrient;GO:0007166//cell surface receptor signaling pathway;GO:0007218//neuropeptide signaling pathway;GO:0071392//cellular response to estradiol stimulus;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007283//spermatogenesis;GO:0030900//forebrain development;GO:0007215//glutamate receptor signaling pathway;GO:0008285//negative regulation of cell proliferation",GO:0004994//somatostatin receptor activity,K04217//Neuroactive ligand-receptor interaction
6752,0,0,0,0,0,6,3,0,25,0,0,0,SSTR2;somatostatin receptor 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0007193//adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway;GO:0021549//cerebellum development;GO:0007267//cell-cell signaling;GO:0008285//negative regulation of cell proliferation;GO:0030900//forebrain development;GO:0030432//peristalsis;GO:0071392//cellular response to estradiol stimulus;GO:0007218//neuropeptide signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007586//digestion;GO:0007283//spermatogenesis;GO:0006937//regulation of muscle contraction;GO:0007584//response to nutrient",GO:0005515//protein binding;GO:0004994//somatostatin receptor activity;GO:0030165//PDZ domain binding,K04218//Gastric acid secretion;Neuroactive ligand-receptor interaction
6753,0,1,41,0,0,19,0,0,5,0,0,0,SSTR3;somatostatin receptor 3,GO:0060170//ciliary membrane;GO:0005887//integral component of plasma membrane;GO:0031513//nonmotile primary cilium;GO:0005737//cytoplasm;GO:0005886//plasma membrane,"GO:0007267//cell-cell signaling;GO:0021549//cerebellum development;GO:0008628//hormone-mediated apoptotic signaling pathway;GO:0071385//cellular response to glucocorticoid stimulus;GO:0071392//cellular response to estradiol stimulus;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0038170//somatostatin signaling pathway;GO:0042594//response to starvation;GO:0008285//negative regulation of cell proliferation;GO:0030900//forebrain development;GO:0007283//spermatogenesis",GO:0005515//protein binding;GO:0004994//somatostatin receptor activity,K04219//Neuroactive ligand-receptor interaction
6754,0,0,0,0,0,0,2,0,0,0,0,0,SSTR4;somatostatin receptor 4,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane,"GO:0030900//forebrain development;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0019369//arachidonic acid metabolic process;GO:0038170//somatostatin signaling pathway;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0030815//negative regulation of cAMP metabolic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0016477//cell migration;GO:0043410//positive regulation of MAPK cascade",GO:0004994//somatostatin receptor activity,K04220//Neuroactive ligand-receptor interaction
6755,2,0,0,0,19,0,0,0,19,0,0,0,SSTR5;somatostatin receptor 5,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0032467//positive regulation of cytokinesis;GO:0038170//somatostatin signaling pathway;GO:0042593//glucose homeostasis;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0050796//regulation of insulin secretion;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway",GO:0004994//somatostatin receptor activity,K04221//Neuroactive ligand-receptor interaction
6756,0,0,0,0,0,11,16,0,38,0,0,0,"SSX1;synovial sarcoma, X breakpoint 1",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0003714//transcription corepressor activity,K15624//Transcriptional misregulation in cancer;K15625//Transcriptional misregulation in cancer
6758,75,0,0,0,0,0,0,0,1,0,0,0,"SSX5;synovial sarcoma, X breakpoint 5",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003676//nucleic acid binding,K15624//Transcriptional misregulation in cancer;K15625//Transcriptional misregulation in cancer
676,84,0,0,0,0,45,0,0,52,0,0,0,"BRDT;bromodomain, testis-specific",GO:0005634//nucleus,"GO:0006338//chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0043484//regulation of RNA splicing;GO:0030154//cell differentiation;GO:0001207//histone displacement;GO:0051039//positive regulation of transcription during meiosis;GO:0007141//male meiosis I;GO:0007140//male meiosis",GO:0070577//lysine-acetylated histone binding;GO:0003713//transcription coactivator activity;GO:0042393//histone binding,-
6760,0,40,0,92,122,7,21,0,58,0,0,0,"SS18;synovial sarcoma translocation, chromosome 18",GO:0005634//nucleus;GO:0005881//cytoplasmic microtubule,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0000902//cell morphogenesis;GO:0042493//response to drug;GO:0000226//microtubule cytoskeleton organization;GO:0048013//ephrin receptor signaling pathway;GO:0035556//intracellular signal transduction",GO:0005515//protein binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,K15623//Transcriptional misregulation in cancer
6764,43,0,0,0,1,2,0,0,25,0,42,0,ST5;suppression of tumorigenicity 5,-,GO:0032851//positive regulation of Rab GTPase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
6767,4,49,0,154,730,0,1,2,33,0,2,0,ST13;suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein),GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0061084//negative regulation of protein refolding;GO:0006457//protein folding;GO:0051260//protein homooligomerization;GO:0070389//chaperone cofactor-dependent protein refolding,"GO:0032564//dATP binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0019904//protein domain specific binding;GO:0051087//chaperone binding;GO:0032403//protein complex binding;GO:0030674//protein binding, bridging;GO:0042802//identical protein binding;GO:0030544//Hsp70 protein binding",-
6768,106,8,1,1,1,0,0,0,39,129,7,66,ST14;suppression of tumorigenicity 14 (colon carcinoma),GO:0005887//integral component of plasma membrane;GO:0019897//extrinsic component of plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030216//keratinocyte differentiation;GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity,-
6769,0,0,0,0,0,26,18,37,42,0,3,0,STAC;SH3 and cysteine rich domain,GO:0005829//cytosol,GO:0034605//cellular response to heat;GO:0035556//intracellular signal transduction;GO:0007165//signal transduction,GO:0046872//metal ion binding;GO:0005515//protein binding,K06114//Tight junction;K07366//T cell receptor signaling pathway
677,0,0,1,4,48,0,0,0,22,0,0,0,ZFP36L1;ZFP36 ring finger protein-like 1,GO:0005634//nucleus;GO:0005829//cytosol,"GO:0043488//regulation of mRNA stability;GO:0033077//T cell differentiation in thymus;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0006417//regulation of translation;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0001570//vasculogenesis",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003729//mRNA binding;GO:0003677//DNA binding,K15308//HTLV-I infection
6770,28,0,0,0,18,0,0,0,32,195,8,0,STAR;steroidogenic acute regulatory protein,GO:0030061//mitochondrial crista;GO:0043025//neuronal cell body;GO:0005758//mitochondrial intermembrane space;GO:0043005//neuron projection;GO:0005829//cytosol,"GO:0042747//circadian sleep/wake cycle, REM sleep;GO:0048168//regulation of neuronal synaptic plasticity;GO:0035457//cellular response to interferon-alpha;GO:0007420//brain development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0010288//response to lead ion;GO:0042542//response to hydrogen peroxide;GO:0014823//response to activity;GO:0010628//positive regulation of gene expression;GO:0071872//cellular response to epinephrine stimulus;GO:0032869//cellular response to insulin stimulus;GO:0050769//positive regulation of neurogenesis;GO:0006703//estrogen biosynthetic process;GO:0035094//response to nicotine;GO:0071222//cellular response to lipopolysaccharide;GO:0071312//cellular response to alkaloid;GO:0043524//negative regulation of neuron apoptotic process;GO:0050810//regulation of steroid biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0008584//male gonad development;GO:0060992//response to fungicide;GO:0071320//cellular response to cAMP;GO:0032367//intracellular cholesterol transport;GO:0050756//fractalkine metabolic process;GO:0051412//response to corticosterone;GO:0071549//cellular response to dexamethasone stimulus;GO:0010212//response to ionizing radiation;GO:0044281//small molecule metabolic process;GO:0006694//steroid biosynthetic process;GO:0042493//response to drug;GO:0006700//C21-steroid hormone biosynthetic process;GO:0071378//cellular response to growth hormone stimulus;GO:0071236//cellular response to antibiotic;GO:0006701//progesterone biosynthetic process;GO:0018879//biphenyl metabolic process;GO:0045471//response to ethanol;GO:0071372//cellular response to follicle-stimulating hormone stimulus;GO:0008203//cholesterol metabolic process;GO:0071276//cellular response to cadmium ion;GO:0018963//phthalate metabolic process;GO:0044321//response to leptin;GO:0008202//steroid metabolic process;GO:0018894//dibenzo-p-dioxin metabolic process;GO:0016101//diterpenoid metabolic process;GO:0071346//cellular response to interferon-gamma;GO:0017143//insecticide metabolic process;GO:0071373//cellular response to luteinizing hormone stimulus;GO:0008211//glucocorticoid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0043627//response to estrogen;GO:0018958//phenol-containing compound metabolic process;GO:0009635//response to herbicide;GO:0007584//response to nutrient;GO:0061370//testosterone biosynthetic process",GO:0015485//cholesterol binding,K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
6772,186,66,0,95,350,13,1,13,4,1,22,0,"STAT1;signal transducer and activator of transcription 1, 91kDa",GO:0005730//nucleolus;GO:0030424//axon;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0030425//dendrite;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0032869//cellular response to insulin stimulus;GO:0043330//response to exogenous dsRNA;GO:0042542//response to hydrogen peroxide;GO:0061326//renal tubule development;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0035458//cellular response to interferon-beta;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0016032//viral process;GO:0016525//negative regulation of angiogenesis;GO:0072308//negative regulation of metanephric nephron tubule epithelial cell differentiation;GO:0034240//negative regulation of macrophage fusion;GO:0007259//JAK-STAT cascade;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0072136//metanephric mesenchymal cell proliferation involved in metanephros development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0072162//metanephric mesenchymal cell differentiation;GO:0042493//response to drug;GO:0045893//positive regulation of transcription, DNA-templated;GO:0003340//negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0007584//response to nutrient;GO:0006366//transcription from RNA polymerase II promoter;GO:0009612//response to mechanical stimulus;GO:0006915//apoptotic process;GO:0034097//response to cytokine;GO:0043434//response to peptide hormone;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0051607//defense response to virus;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0042981//regulation of apoptotic process;GO:0051591//response to cAMP;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043542//endothelial cell migration;GO:0008015//blood circulation;GO:0001937//negative regulation of endothelial cell proliferation",GO:0005164//tumor necrosis factor receptor binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0003690//double-stranded DNA binding;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0031730//CCR5 chemokine receptor binding,K11220//Measles;Hepatitis C;Herpes simplex infection;Leishmaniasis;Osteoclast differentiation;Toxoplasmosis;Toll-like receptor signaling pathway;Influenza A;Tuberculosis;Pancreatic cancer;Jak-STAT signaling pathway;Pathways in cancer;Chemokine signaling pathway
6773,0,0,0,10,33,0,39,0,19,0,0,0,"STAT2;signal transducer and activator of transcription 2, 113kDa",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0006351//transcription, DNA-templated;GO:0007259//JAK-STAT cascade;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway",GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005509//calcium ion binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity,K11221//Measles;Influenza A;Chemokine signaling pathway;Osteoclast differentiation;Herpes simplex infection;Jak-STAT signaling pathway;Hepatitis C
6774,0,133,0,80,238,0,0,56,48,0,16,0,STAT3;signal transducer and activator of transcription 3 (acute-phase response factor),GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0042493//response to drug;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0006953//acute-phase response;GO:0001659//temperature homeostasis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045471//response to ethanol;GO:0032870//cellular response to hormone stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016310//phosphorylation;GO:0070102//interleukin-6-mediated signaling pathway;GO:0007165//signal transduction;GO:0006366//transcription from RNA polymerase II promoter;GO:0006928//cellular component movement;GO:0007399//nervous system development;GO:0019221//cytokine-mediated signaling pathway;GO:0045747//positive regulation of Notch signaling pathway;GO:2001223//negative regulation of neuron migration;GO:0042593//glucose homeostasis;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0060396//growth hormone receptor signaling pathway;GO:0008283//cell proliferation;GO:0019953//sexual reproduction;GO:0001754//eye photoreceptor cell differentiation;GO:0048708//astrocyte differentiation;GO:0008285//negative regulation of cell proliferation;GO:0030522//intracellular receptor signaling pathway;GO:0006606//protein import into nucleus;GO:0016032//viral process;GO:0040014//regulation of multicellular organism growth;GO:0060019//radial glial cell differentiation;GO:0007259//JAK-STAT cascade;GO:0032355//response to estradiol;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042755//eating behavior;GO:0060548//negative regulation of cell death;GO:0045820//negative regulation of glycolytic process;GO:0019827//stem cell maintenance",GO:0035259//glucocorticoid receptor binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005509//calcium ion binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0031730//CCR5 chemokine receptor binding;GO:0046983//protein dimerization activity;GO:0019903//protein phosphatase binding;GO:0001103//RNA polymerase II repressing transcription factor binding,K04692//Pancreatic cancer;Jak-STAT signaling pathway;Acute myeloid leukemia;Pathways in cancer;Chemokine signaling pathway;Epstein-Barr virus infection;Measles;Hepatitis C;Adipocytokine signaling pathway;Toxoplasmosis
6775,0,0,0,0,0,10,0,6,68,0,0,0,STAT4;signal transducer and activator of transcription 4,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007259//JAK-STAT cascade;GO:0006468//protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0005509//calcium ion binding,K11222//Jak-STAT signaling pathway
6776,0,0,0,0,32,15,0,0,14,0,0,0,STAT5A;signal transducer and activator of transcription 5A,GO:0005654//nucleoplasm;GO:0005829//cytosol,"GO:0033026//negative regulation of mast cell apoptotic process;GO:0060376//positive regulation of mast cell differentiation;GO:0006101//citrate metabolic process;GO:0061180//mammary gland epithelium development;GO:0060742//epithelial cell differentiation involved in prostate gland development;GO:0038161//prolactin signaling pathway;GO:0006600//creatine metabolic process;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006631//fatty acid metabolic process;GO:0046449//creatinine metabolic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0006105//succinate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006107//oxaloacetate metabolic process;GO:0030856//regulation of epithelial cell differentiation;GO:0019530//taurine metabolic process;GO:0001779//natural killer cell differentiation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0019218//regulation of steroid metabolic process;GO:0006573//valine metabolic process;GO:0042104//positive regulation of activated T cell proliferation;GO:0097011//cellular response to granulocyte macrophage colony-stimulating factor stimulus;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0060740//prostate gland epithelium morphogenesis;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0048541//Peyer's patch development;GO:0007565//female pregnancy;GO:0045931//positive regulation of mitotic cell cycle;GO:0045647//negative regulation of erythrocyte differentiation;GO:0046544//development of secondary male sexual characteristics;GO:0006549//isoleucine metabolic process;GO:0043029//T cell homeostasis;GO:0006351//transcription, DNA-templated;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0046543//development of secondary female sexual characteristics;GO:0040014//regulation of multicellular organism growth;GO:0000255//allantoin metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0040018//positive regulation of multicellular organism growth;GO:0007595//lactation;GO:0045579//positive regulation of B cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007259//JAK-STAT cascade;GO:0050729//positive regulation of inflammatory response;GO:0030155//regulation of cell adhesion;GO:0001553//luteinization;GO:0033077//T cell differentiation in thymus;GO:0070668//positive regulation of mast cell proliferation;GO:0019915//lipid storage",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005509//calcium ion binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0019903//protein phosphatase binding,K11223//Pathways in cancer;Jak-STAT signaling pathway;Acute myeloid leukemia;Chronic myeloid leukemia;HTLV-I infection;Measles;ErbB signaling pathway
6777,98,0,1,19,25,36,0,58,8,143,0,0,STAT5B;signal transducer and activator of transcription 5B,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007565//female pregnancy;GO:0045931//positive regulation of mitotic cell cycle;GO:0048541//Peyer's patch development;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0006549//isoleucine metabolic process;GO:0046544//development of secondary male sexual characteristics;GO:0043029//T cell homeostasis;GO:0001889//liver development;GO:0070670//response to interleukin-4;GO:0045647//negative regulation of erythrocyte differentiation;GO:0070669//response to interleukin-2;GO:0032819//positive regulation of natural killer cell proliferation;GO:0051272//positive regulation of cellular component movement;GO:0046543//development of secondary female sexual characteristics;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0043066//negative regulation of apoptotic process;GO:0040018//positive regulation of multicellular organism growth;GO:0007595//lactation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0040014//regulation of multicellular organism growth;GO:0000255//allantoin metabolic process;GO:0006103//2-oxoglutarate metabolic process;GO:0007259//JAK-STAT cascade;GO:0045579//positive regulation of B cell differentiation;GO:0032355//response to estradiol;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050729//positive regulation of inflammatory response;GO:0030155//regulation of cell adhesion;GO:0033077//T cell differentiation in thymus;GO:0001553//luteinization;GO:0019915//lipid storage;GO:0070672//response to interleukin-15;GO:0006953//acute-phase response;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0032496//response to lipopolysaccharide;GO:0006101//citrate metabolic process;GO:0038161//prolactin signaling pathway;GO:0006600//creatine metabolic process;GO:0006631//fatty acid metabolic process;GO:0046449//creatinine metabolic process;GO:0045954//positive regulation of natural killer cell mediated cytotoxicity;GO:0045471//response to ethanol;GO:0030856//regulation of epithelial cell differentiation;GO:0032825//positive regulation of natural killer cell differentiation;GO:0001779//natural killer cell differentiation;GO:0032870//cellular response to hormone stimulus;GO:0019530//taurine metabolic process;GO:0006107//oxaloacetate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006105//succinate metabolic process;GO:0042104//positive regulation of activated T cell proliferation;GO:0019218//regulation of steroid metabolic process;GO:0006573//valine metabolic process;GO:0006366//transcription from RNA polymerase II promoter;GO:0042448//progesterone metabolic process;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0001666//response to hypoxia;GO:0071363//cellular response to growth factor stimulus,GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0046983//protein dimerization activity;GO:0003682//chromatin binding;GO:0019903//protein phosphatase binding;GO:0035259//glucocorticoid receptor binding;GO:0005509//calcium ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding,K11224//Pathways in cancer;Chemokine signaling pathway;Acute myeloid leukemia;Jak-STAT signaling pathway;HTLV-I infection;Chronic myeloid leukemia;Measles;ErbB signaling pathway
677765,0,0,0,0,0,0,26,0,0,0,0,0,SCARNA18;small Cajal body-specific RNA 18,-,-,-,-
677795,30,0,0,0,0,0,0,0,0,0,0,0,"SNORA5B;small nucleolar RNA, H/ACA box 5B",-,-,-,-
6778,102,56,20,17,58,0,36,72,8,0,20,0,"STAT6;signal transducer and activator of transcription 6, interleukin-4 induced",GO:0005737//cytoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0045121//membrane raft,"GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0033598//mammary gland epithelial cell proliferation;GO:0070301//cellular response to hydrogen peroxide;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060443//mammary gland morphogenesis;GO:0048295//positive regulation of isotype switching to IgE isotypes;GO:0042127//regulation of cell proliferation;GO:0002296//T-helper 1 cell lineage commitment;GO:0035771//interleukin-4-mediated signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:1902170//cellular response to reactive nitrogen species;GO:0002829//negative regulation of type 2 immune response",GO:0019903//protein phosphatase binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K11225//Jak-STAT signaling pathway
677812,0,0,0,0,0,0,0,0,19,0,0,0,"SNORA29;small nucleolar RNA, H/ACA box 29",-,-,-,-
677826,0,0,0,0,0,0,0,0,8,0,0,0,"SNORA45B;small nucleolar RNA, H/ACA box 45B",-,-,-,-
677827,0,0,0,0,0,0,0,0,28,0,0,0,"SNORA46;small nucleolar RNA, H/ACA box 46",-,-,-,-
677829,0,0,0,0,0,0,0,0,14,0,0,0,"SNORA49;small nucleolar RNA, H/ACA box 49",-,-,-,-
678,0,0,0,17,46,36,0,57,35,0,1,1,ZFP36L2;ZFP36 ring finger protein-like 2,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0060216//definitive hemopoiesis;GO:0048103//somatic stem cell division;GO:0006355//regulation of transcription, DNA-templated;GO:0035019//somatic stem cell maintenance;GO:2000737//negative regulation of stem cell differentiation;GO:0008283//cell proliferation;GO:0043488//regulation of mRNA stability;GO:0030097//hemopoiesis;GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0033077//T cell differentiation in thymus;GO:0006402//mRNA catabolic process",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0003677//DNA binding;GO:0017091//AU-rich element binding,K15308//HTLV-I infection
6780,53,69,47,18,195,0,1,0,57,0,20,0,STAU1;staufen double-stranded RNA binding protein 1,GO:0044297//cell body;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0016020//membrane;GO:0010494//cytoplasmic stress granule;GO:0005791//rough endoplasmic reticulum;GO:0005875//microtubule associated complex,GO:0008298//intracellular mRNA localization,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008157//protein phosphatase 1 binding;GO:0003725//double-stranded RNA binding,K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
6781,0,0,0,0,0,17,0,0,43,211,7,0,STC1;stanniocalcin 1,GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0071456//cellular response to hypoxia;GO:0001503//ossification;GO:0007267//cell-cell signaling;GO:0006874//cellular calcium ion homeostasis;GO:0030336//negative regulation of cell migration;GO:0007566//embryo implantation;GO:0086004//regulation of cardiac muscle cell contraction;GO:0001886//endothelial cell morphogenesis;GO:0035988//chondrocyte proliferation;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033280//response to vitamin D;GO:0044070//regulation of anion transport;GO:0046697//decidualization;GO:0010596//negative regulation of endothelial cell migration;GO:0060348//bone development;GO:0071320//cellular response to cAMP;GO:0007584//response to nutrient;GO:0090280//positive regulation of calcium ion import;GO:0007166//cell surface receptor signaling pathway,GO:0005179//hormone activity,-
6782,176,0,0,0,0,55,46,0,18,0,0,0,"HSPA13;heat shock protein 70kDa family, member 13",GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0070062//extracellular vesicular exosome,-,GO:0005524//ATP binding,-
6783,0,0,0,0,0,0,0,0,14,0,0,0,"SULT1E1;sulfotransferase family 1E, estrogen-preferring, member 1",GO:0005829//cytosol,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0008202//steroid metabolic process;GO:0051923//sulfation;GO:0007565//female pregnancy;GO:0008210//estrogen metabolic process,GO:0005496//steroid binding;GO:0050294//steroid sulfotransferase activity;GO:0047894//flavonol 3-sulfotransferase activity;GO:0004304//estrone sulfotransferase activity,K01016//Steroid hormone biosynthesis;Sulfur metabolism
6785,0,0,0,0,0,0,20,0,2,0,0,0,ELOVL4;ELOVL fatty acid elongase 4,GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane,"GO:0006633//fatty acid biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0009584//detection of visible light;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process",GO:0016740//transferase activity;GO:0005515//protein binding;GO:0008020//G-protein coupled photoreceptor activity,K10249//Fatty acid elongation
6786,0,1,0,4,0,0,22,39,27,0,0,0,STIM1;stromal interaction molecule 1,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005874//microtubule;GO:0030426//growth cone;GO:0032541//cortical endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,GO:0007596//blood coagulation;GO:2001256//regulation of store-operated calcium entry;GO:0002115//store-operated calcium entry;GO:0032237//activation of store-operated calcium channel activity;GO:0070588//calcium ion transmembrane transport;GO:0051924//regulation of calcium ion transport;GO:0005513//detection of calcium ion,GO:0051010//microtubule plus-end binding;GO:0005246//calcium channel regulator activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0015279//store-operated calcium channel activity;GO:0005509//calcium ion binding,K16059//Calcium signaling pathway
6787,0,55,1,50,219,5,27,0,24,0,0,0,NEK4;NIMA-related kinase 4,GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0007067//mitotic nuclear division,GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding,-
6788,0,15,0,31,106,0,0,0,26,0,0,0,STK3;serine/threonine kinase 3,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006915//apoptotic process;GO:0006468//protein phosphorylation;GO:0035329//hippo signaling;GO:0043065//positive regulation of apoptotic process;GO:0046621//negative regulation of organ growth;GO:0007165//signal transduction;GO:0097284//hepatocyte apoptotic process;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0046330//positive regulation of JNK cascade;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0035556//intracellular signal transduction;GO:0001841//neural tube formation;GO:0003157//endocardium development;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0051897//positive regulation of protein kinase B signaling;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060215//primitive hemopoiesis,GO:0043539//protein serine/threonine kinase activator activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K04412//MAPK signaling pathway
6789,33,0,0,19,50,10,24,0,52,0,7,0,STK4;serine/threonine kinase 4,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0001569//patterning of blood vessels;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0007165//signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0046621//negative regulation of organ growth;GO:0006468//protein phosphorylation;GO:0035329//hippo signaling;GO:0000902//cell morphogenesis;GO:0030216//keratinocyte differentiation;GO:0006915//apoptotic process;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0060215//primitive hemopoiesis;GO:0003157//endocardium development;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0001841//neural tube formation;GO:0035556//intracellular signal transduction;GO:0007417//central nervous system development;GO:0008285//negative regulation of cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0097284//hepatocyte apoptotic process,GO:0042802//identical protein binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0046983//protein dimerization activity;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding,K04411//Pathways in cancer;MAPK signaling pathway;Non-small cell lung cancer
6790,0,1,0,0,0,20,0,0,41,0,0,0,AURKA;aurora kinase A,GO:0072686//mitotic spindle;GO:0045120//pronucleus;GO:0031616//spindle pole centrosome;GO:0005813//centrosome;GO:0042585//germinal vesicle;GO:0043203//axon hillock;GO:0005819//spindle;GO:0030496//midbody;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0072687//meiotic spindle,GO:0051642//centrosome localization;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0046605//regulation of centrosome cycle;GO:0031647//regulation of protein stability;GO:0043066//negative regulation of apoptotic process;GO:0032091//negative regulation of protein binding;GO:1990138//neuron projection extension;GO:0043146//spindle stabilization;GO:0007067//mitotic nuclear division;GO:0046777//protein autophosphorylation;GO:0009948//anterior/posterior axis specification;GO:0035404//histone-serine phosphorylation;GO:1900195//positive regulation of oocyte maturation;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0071539//protein localization to centrosome;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007052//mitotic spindle organization;GO:0006468//protein phosphorylation;GO:0045840//positive regulation of mitosis;GO:0007100//mitotic centrosome separation;GO:0007057//spindle assembly involved in female meiosis I,GO:0005524//ATP binding;GO:0035174//histone serine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K11481//Progesterone-mediated oocyte maturation;Oocyte meiosis
6792,0,0,1,11,113,8,0,0,24,0,1,0,CDKL5;cyclin-dependent kinase-like 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032839//dendrite cytoplasm;GO:0005730//nucleolus;GO:0044294//dendritic growth cone;GO:0032587//ruffle membrane,GO:0045773//positive regulation of axon extension;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0001764//neuron migration;GO:0032855//positive regulation of Rac GTPase activity;GO:0046777//protein autophosphorylation;GO:0050775//positive regulation of dendrite morphogenesis;GO:0050773//regulation of dendrite development,GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0048365//Rac GTPase binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0016301//kinase activity,-
6793,1,0,0,0,7,41,23,5,41,0,0,0,STK10;serine/threonine kinase 10,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation;GO:0023014//signal transduction by phosphorylation;GO:0007049//cell cycle;GO:2000401//regulation of lymphocyte migration;GO:0046777//protein autophosphorylation;GO:0071593//lymphocyte aggregation,GO:0042801//polo kinase kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0004674//protein serine/threonine kinase activity,-
6794,0,41,1,0,12,0,8,1,11,0,0,0,STK11;serine/threonine kinase 11,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0036398//TCR signalosome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0051896//regulation of protein kinase B signaling;GO:0060070//canonical Wnt signaling pathway;GO:0045059//positive thymic T cell selection;GO:0044281//small molecule metabolic process;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0010212//response to ionizing radiation;GO:0007409//axonogenesis;GO:0030010//establishment of cell polarity;GO:0036399//TCR signalosome assembly;GO:0045722//positive regulation of gluconeogenesis;GO:0006468//protein phosphorylation;GO:0051291//protein heterooligomerization;GO:0046777//protein autophosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0050772//positive regulation of axonogenesis;GO:0007286//spermatid development;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0051645//Golgi localization;GO:0032147//activation of protein kinase activity;GO:0042304//regulation of fatty acid biosynthetic process;GO:0033762//response to glucagon;GO:0033993//response to lipid;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0001558//regulation of cell growth;GO:0030111//regulation of Wnt signaling pathway;GO:0042593//glucose homeostasis;GO:0001894//tissue homeostasis;GO:0050852//T cell receptor signaling pathway;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0001944//vasculature development;GO:0008286//insulin receptor signaling pathway;GO:0043276//anoikis;GO:0006112//energy reserve metabolic process;GO:0006914//autophagy;GO:0007050//cell cycle arrest,GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0002039//p53 binding;GO:0030295//protein kinase activator activity;GO:0000287//magnesium ion binding;GO:0030275//LRR domain binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K07298//mTOR signaling pathway;Adipocytokine signaling pathway
6799,0,0,0,0,0,0,2,0,0,0,0,0,"SULT1A2;sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2",GO:0005829//cytosol,GO:0006805//xenobiotic metabolic process;GO:0009309//amine biosynthetic process;GO:0006584//catecholamine metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0008202//steroid metabolic process;GO:0051923//sulfation;GO:0018958//phenol-containing compound metabolic process,GO:0047894//flavonol 3-sulfotransferase activity;GO:0004062//aryl sulfotransferase activity;GO:0008146//sulfotransferase activity,K01014//Sulfur metabolism;Microbial metabolism in diverse environments
680,0,0,0,0,0,29,0,0,0,0,0,0,BRS3;bombesin-like receptor 3,GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0005886//plasma membrane,GO:0006006//glucose metabolic process;GO:0031989//bombesin receptor signaling pathway;GO:0008217//regulation of blood pressure;GO:0008343//adult feeding behavior,GO:0004946//bombesin receptor activity,K04170//Neuroactive ligand-receptor interaction
6801,0,1,0,14,78,0,0,0,25,0,1,0,"STRN;striatin, calmodulin binding protein",GO:0005923//tight junction;GO:0000159//protein phosphatase type 2A complex;GO:0016020//membrane;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0014069//postsynaptic density,GO:0007626//locomotory behavior;GO:0008285//negative regulation of cell proliferation;GO:0016358//dendrite development;GO:0070830//tight junction assembly;GO:0016055//Wnt signaling pathway,GO:0005515//protein binding;GO:0030331//estrogen receptor binding;GO:0051721//protein phosphatase 2A binding;GO:0032403//protein complex binding;GO:0070016//armadillo repeat domain binding;GO:0005516//calmodulin binding,K12857//Spliceosome;K12602//RNA degradation;K01062//Metabolic pathways;Ether lipid metabolism;Biosynthesis of secondary metabolites
6804,41,0,0,0,0,0,0,0,11,0,12,0,STX1A;syntaxin 1A (brain),GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0031201//SNARE complex;GO:0030672//synaptic vesicle membrane;GO:0042641//actomyosin;GO:0030141//secretory granule;GO:0070033//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex;GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070032//synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex,GO:0044281//small molecule metabolic process;GO:0006886//intracellular protein transport;GO:0001956//positive regulation of neurotransmitter secretion;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0044267//cellular protein metabolic process;GO:0045921//positive regulation of exocytosis;GO:0014047//glutamate secretion;GO:0009629//response to gravity;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0017156//calcium ion-dependent exocytosis;GO:0016081//synaptic vesicle docking involved in exocytosis,"GO:0048306//calcium-dependent protein binding;GO:0043008//ATP-dependent protein binding;GO:0032028//myosin head/neck binding;GO:0046982//protein heterodimerization activity;GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding;GO:0001948//glycoprotein binding;GO:0047485//protein N-terminus binding;GO:0019904//protein domain specific binding;GO:0019855//calcium channel inhibitor activity;GO:0030674//protein binding, bridging",K04560//Amphetamine addiction;SNARE interactions in vesicular transport;Synaptic vesicle cycle
6809,76,0,0,27,47,47,0,0,52,0,0,0,STX3;syntaxin 3,GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0005773//vacuole;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0031201//SNARE complex;GO:0042582//azurophil granule;GO:0042581//specific granule;GO:0005911//cell-cell junction;GO:0016324//apical plasma membrane;GO:0030426//growth cone,GO:0060291//long-term synaptic potentiation;GO:0006887//exocytosis;GO:0061025//membrane fusion;GO:0006886//intracellular protein transport;GO:0031175//neuron projection development;GO:0006836//neurotransmitter transport,GO:0050544//arachidonic acid binding;GO:0005484//SNAP receptor activity;GO:0005515//protein binding,K08486//Synaptic vesicle cycle;SNARE interactions in vesicular transport
6810,0,1,0,9,0,0,0,0,0,0,0,0,STX4;syntaxin 4,GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0043219//lateral loop;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031201//SNARE complex;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0005773//vacuole;GO:0042581//specific granule;GO:0035749//myelin sheath adaxonal region;GO:0005802//trans-Golgi network,GO:0006892//post-Golgi vesicle-mediated transport;GO:0007596//blood coagulation;GO:0035493//SNARE complex assembly;GO:0030168//platelet activation;GO:0006886//intracellular protein transport;GO:0006836//neurotransmitter transport;GO:0061024//membrane organization,GO:0005515//protein binding;GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity,K13502//SNARE interactions in vesicular transport;Vasopressin-regulated water reabsorption
6811,0,33,0,6,19,11,3,0,9,0,14,0,STX5;syntaxin 5,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0031201//SNARE complex;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,"GO:0006903//vesicle targeting;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0048280//vesicle fusion with Golgi apparatus;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport",GO:0005515//protein binding;GO:0005484//SNAP receptor activity;GO:0047485//protein N-terminus binding,K08490//SNARE interactions in vesicular transport
6812,88,1,0,18,11,2,8,0,73,0,4,0,STXBP1;syntaxin binding protein 1,GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031091//platelet alpha granule;GO:0043234//protein complex;GO:0005737//cytoplasm,"GO:0007274//neuromuscular synaptic transmission;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0043524//negative regulation of neuron apoptotic process;GO:0006112//energy reserve metabolic process;GO:0060292//long term synaptic depression;GO:0002576//platelet degranulation;GO:0007412//axon target recognition;GO:0010807//regulation of synaptic vesicle priming;GO:0007268//synaptic transmission;GO:0031630//regulation of synaptic vesicle fusion to presynaptic membrane;GO:0044281//small molecule metabolic process;GO:0016188//synaptic vesicle maturation;GO:0006904//vesicle docking involved in exocytosis;GO:0050796//regulation of insulin secretion;GO:0014047//glutamate secretion;GO:0070527//platelet aggregation;GO:0050821//protein stabilization;GO:0032229//negative regulation of synaptic transmission, GABAergic;GO:0007269//neurotransmitter secretion;GO:0015031//protein transport",GO:0044822//poly(A) RNA binding;GO:0000149//SNARE binding;GO:0017075//syntaxin-1 binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0019905//syntaxin binding;GO:0047485//protein N-terminus binding;GO:0019904//protein domain specific binding,K15292//Synaptic vesicle cycle
6813,72,0,0,15,8,0,0,0,11,84,0,0,STXBP2;syntaxin binding protein 2,GO:0031201//SNARE complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0042581//specific granule;GO:0042582//azurophil granule;GO:0044194//cytolytic granule;GO:0005829//cytosol;GO:0070820//tertiary granule,GO:0015031//protein transport;GO:0043312//neutrophil degranulation;GO:0043304//regulation of mast cell degranulation;GO:0001909//leukocyte mediated cytotoxicity;GO:0006904//vesicle docking involved in exocytosis,GO:0030348//syntaxin-3 binding;GO:0005515//protein binding,-
6814,0,2,0,6,23,0,26,0,56,0,11,0,STXBP3;syntaxin binding protein 3,GO:0016324//apical plasma membrane;GO:0042581//specific granule;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0070820//tertiary granule;GO:0031091//platelet alpha granule;GO:0005829//cytosol;GO:0016323//basolateral plasma membrane,GO:0030168//platelet activation;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0007596//blood coagulation;GO:0043312//neutrophil degranulation;GO:0006904//vesicle docking involved in exocytosis;GO:0051291//protein heterooligomerization;GO:0070527//platelet aggregation;GO:0061024//membrane organization;GO:0015031//protein transport,GO:0019905//syntaxin binding;GO:0005515//protein binding;GO:0017075//syntaxin-1 binding,-
6815,77,0,1,1,87,0,56,0,82,5,0,0,STYX;serine/threonine/tyrosine interacting protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0045204//MAPK export from nucleus;GO:0007283//spermatogenesis;GO:0006470//protein dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K04459//MAPK signaling pathway;Transcriptional misregulation in cancer;Serotonergic synapse;K11447//Transcriptional misregulation in cancer
6817,0,0,0,0,0,0,51,49,0,37,0,0,"SULT1A1;sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1",GO:0005829//cytosol,GO:0009308//amine metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0006584//catecholamine metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009812//flavonoid metabolic process;GO:0008210//estrogen metabolic process;GO:0051923//sulfation,GO:0008146//sulfotransferase activity;GO:0050294//steroid sulfotransferase activity;GO:0047894//flavonol 3-sulfotransferase activity;GO:0004062//aryl sulfotransferase activity,K01014//Microbial metabolism in diverse environments;Sulfur metabolism
6819,0,0,0,0,0,0,12,0,0,0,14,0,"SULT1C2;sulfotransferase family, cytosolic, 1C, member 2",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0051923//sulfation;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0009308//amine metabolic process,GO:0008146//sulfotransferase activity,-
682,0,0,0,0,16,12,0,0,1,1,9,1,BSG;basigin (Ok blood group),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0042470//melanosome;GO:0045121//membrane raft;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0002080//acrosomal membrane;GO:0005925//focal adhesion;GO:0042383//sarcolemma;GO:0005739//mitochondrion;GO:0005887//integral component of plasma membrane,GO:0022617//extracellular matrix disassembly;GO:0072661//protein targeting to plasma membrane;GO:0051591//response to cAMP;GO:0030198//extracellular matrix organization;GO:0042475//odontogenesis of dentin-containing tooth;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0050900//leukocyte migration;GO:0044281//small molecule metabolic process;GO:0007596//blood coagulation;GO:0007166//cell surface receptor signaling pathway;GO:0046689//response to mercury ion;GO:0043434//response to peptide hormone;GO:0046697//decidualization;GO:0007566//embryo implantation,GO:0005515//protein binding;GO:0005537//mannose binding,-
6820,0,32,1,3,28,0,0,0,23,0,1,239,"SULT2B1;sulfotransferase family, cytosolic, 2B, member 1",GO:0043231//intracellular membrane-bounded organelle;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0000103//sulfate assimilation;GO:0008202//steroid metabolic process;GO:0006805//xenobiotic metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0004027//alcohol sulfotransferase activity;GO:0050294//steroid sulfotransferase activity,K01015//Steroid hormone biosynthesis;Sulfur metabolism;Microbial metabolism in diverse environments
6821,0,1,0,0,26,0,19,0,2,0,0,0,SUOX;sulfite oxidase,GO:0005759//mitochondrial matrix;GO:0005758//mitochondrial intermembrane space,"GO:0034641//cellular nitrogen compound metabolic process;GO:0044281//small molecule metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0000098//sulfur amino acid catabolic process;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase",GO:0020037//heme binding;GO:0008482//sulfite oxidase activity;GO:0030151//molybdenum ion binding;GO:0009055//electron carrier activity;GO:0043546//molybdopterin cofactor binding,K00387//Nitrogen metabolism;Microbial metabolism in diverse environments;Sulfur metabolism
6822,0,0,0,0,0,31,19,0,33,0,0,0,"SULT2A1;sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1",GO:0005829//cytosol,GO:0007586//digestion;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0006805//xenobiotic metabolic process;GO:0030573//bile acid catabolic process;GO:0051923//sulfation;GO:0008202//steroid metabolic process,GO:0005515//protein binding;GO:0047704//bile-salt sulfotransferase activity;GO:0008146//sulfotransferase activity,K11822//Bile secretion;Metabolism of xenobiotics by cytochrome P450
6827,1,51,0,12,36,0,0,74,1,0,6,0,SUPT4H1;suppressor of Ty 4 homolog 1 (S. cerevisiae),GO:0032044//DSIF complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0050434//positive regulation of viral transcription;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0032785//negative regulation of DNA-templated transcription, elongation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006338//chromatin remodeling",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0008270//zinc ion binding,-
6829,49,0,1,13,35,0,44,1,39,0,1,0,SUPT5H;suppressor of Ty 5 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0032044//DSIF complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0039692//single stranded viral RNA replication via double stranded DNA intermediate;GO:0006338//chromatin remodeling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0016239//positive regulation of macroautophagy;GO:0032785//negative regulation of DNA-templated transcription, elongation;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010033//response to organic substance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0007049//cell cycle;GO:0050434//positive regulation of viral transcription",GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,-
6830,106,51,0,22,44,43,32,0,14,196,9,0,SUPT6H;suppressor of Ty 6 homolog (S. cerevisiae),GO:0005634//nucleus,"GO:0050684//regulation of mRNA processing;GO:0006355//regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0010793//regulation of mRNA export from nucleus;GO:0051028//mRNA transport;GO:0061086//negative regulation of histone H3-K27 methylation;GO:0051147//regulation of muscle cell differentiation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045191//regulation of isotype switching;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling","GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042393//histone binding;GO:0016788//hydrolase activity, acting on ester bonds",-
6833,113,0,0,0,0,27,40,180,45,0,3,344,"ABCC8;ATP-binding cassette, sub-family C (CFTR/MRP), member 8",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0006813//potassium ion transport;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0007165//signal transduction;GO:0005975//carbohydrate metabolic process,"GO:0008281//sulfonylurea receptor activity;GO:0005524//ATP binding;GO:0044325//ion channel binding;GO:0015079//potassium ion transmembrane transporter activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05032//Type II diabetes mellitus;ABC transporters
6834,0,10,0,0,1,19,24,0,0,0,1,0,SURF1;surfeit 1,GO:0005746//mitochondrial respiratory chain;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:1902600//hydrogen ion transmembrane transport;GO:0006754//ATP biosynthetic process;GO:0006119//oxidative phosphorylation;GO:0009060//aerobic respiration;GO:0008535//respiratory chain complex IV assembly,GO:0005515//protein binding;GO:0004129//cytochrome-c oxidase activity,-
6835,0,0,0,0,18,0,0,32,24,0,0,0,SURF2;surfeit 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane,-,-,-
6836,0,78,1,3,17,0,52,111,51,0,7,0,SURF4;surfeit 4,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0032527//protein exit from endoplasmic reticulum;GO:0010638//positive regulation of organelle organization;GO:0007030//Golgi organization;GO:0034498//early endosome to Golgi transport,GO:0005515//protein binding,-
6837,1,3,1,0,3,0,25,0,37,0,0,0,MED22;mediator complex subunit 22,GO:0005737//cytoplasm;GO:0016592//mediator complex,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,-
6838,0,1,32,10,0,29,25,0,21,0,5,0,SURF6;surfeit 6,GO:0005654//nucleoplasm;GO:0001652//granular component;GO:0005730//nucleolus,GO:0042254//ribosome biogenesis,GO:0003723//RNA binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
6839,118,0,0,0,5,0,0,0,22,170,0,0,SUV39H1;suppressor of variegation 3-9 homolog 1 (Drosophila),"GO:0005654//nucleoplasm;GO:0005652//nuclear lamina;GO:0033553//rDNA heterochromatin;GO:0005677//chromatin silencing complex;GO:0000794//condensed nuclear chromosome;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0000792//heterochromatin","GO:0036123//histone H3-K9 dimethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006325//chromatin organization;GO:0006364//rRNA processing;GO:0030154//cell differentiation;GO:0016032//viral process;GO:0048511//rhythmic process;GO:0042754//negative regulation of circadian rhythm;GO:0036124//histone H3-K9 trimethylation;GO:0000183//chromatin silencing at rDNA;GO:0007049//cell cycle",GO:0003682//chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0047485//protein N-terminus binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0008270//zinc ion binding;GO:0042054//histone methyltransferase activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0008757//S-adenosylmethionine-dependent methyltransferase activity,K11419//Lysine degradation
684,0,0,0,0,0,0,0,0,15,0,8,0,BST2;bone marrow stromal cell antigen 2,GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0031225//anchored component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0005770//late endosome;GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,GO:0006959//humoral immune response;GO:0045071//negative regulation of viral genome replication;GO:0010951//negative regulation of endopeptidase activity;GO:0034341//response to interferon-gamma;GO:0007275//multicellular organismal development;GO:0051607//defense response to virus;GO:0007165//signal transduction;GO:0042113//B cell activation;GO:0008283//cell proliferation;GO:0002737//negative regulation of plasmacytoid dendritic cell cytokine production;GO:0009615//response to virus;GO:1901253//negative regulation of intracellular transport of viral material;GO:0035456//response to interferon-beta;GO:0030336//negative regulation of cell migration;GO:0032956//regulation of actin cytoskeleton organization;GO:0030308//negative regulation of cell growth;GO:0007267//cell-cell signaling;GO:0045087//innate immune response;GO:0035455//response to interferon-alpha;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0004871//signal transducer activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0042803//protein homodimerization activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
6840,140,146,50,123,250,56,24,247,99,130,139,0,SVIL;supervillin,GO:0005737//cytoplasm;GO:0043034//costamere;GO:0071437//invadopodium;GO:0005886//plasma membrane;GO:0002102//podosome;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion,GO:0007010//cytoskeleton organization;GO:0007519//skeletal muscle tissue development,GO:0005515//protein binding;GO:0051015//actin filament binding,-
6843,0,45,0,0,17,0,2,0,9,0,0,0,VAMP1;vesicle-associated membrane protein 1 (synaptobrevin 1),GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0043005//neuron projection;GO:0030672//synaptic vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0005741//mitochondrial outer membrane;GO:0030054//cell junction,GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0035493//SNARE complex assembly,GO:0005515//protein binding,K08510//SNARE interactions in vesicular transport
6844,0,1,0,13,48,15,0,1,0,0,1,0,VAMP2;vesicle-associated membrane protein 2 (synaptobrevin 2),GO:0008021//synaptic vesicle;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0031201//SNARE complex;GO:0005886//plasma membrane;GO:0030672//synaptic vesicle membrane;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0030667//secretory granule membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0044306//neuron projection terminus,GO:0061024//membrane organization;GO:0007268//synaptic transmission;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0044267//cellular protein metabolic process;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0014047//glutamate secretion;GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0044281//small molecule metabolic process,GO:0005515//protein binding;GO:0043621//protein self-association,K13504//Synaptic vesicle cycle;SNARE interactions in vesicular transport;Salivary secretion;Vasopressin-regulated water reabsorption
6845,0,36,0,24,85,8,34,0,40,0,0,0,VAMP7;vesicle-associated membrane protein 7,GO:0070062//extracellular vesicular exosome;GO:0045202//synapse;GO:0009986//cell surface;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane;GO:0030658//transport vesicle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0031201//SNARE complex;GO:0030670//phagocytic vesicle membrane;GO:0005886//plasma membrane;GO:0045335//phagocytic vesicle;GO:0030054//cell junction;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0045177//apical part of cell;GO:0031902//late endosome membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane,"GO:0016192//vesicle-mediated transport;GO:0000046//autophagic vacuole fusion;GO:0043308//eosinophil degranulation;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0043312//neutrophil degranulation;GO:0017156//calcium ion-dependent exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006911//phagocytosis, engulfment;GO:0048280//vesicle fusion with Golgi apparatus;GO:0034197//triglyceride transport;GO:0043001//Golgi to plasma membrane protein transport;GO:1900483//regulation of protein targeting to vacuolar membrane;GO:0006906//vesicle fusion;GO:0035493//SNARE complex assembly;GO:0008333//endosome to lysosome transport;GO:0061024//membrane organization",GO:0005515//protein binding;GO:0019905//syntaxin binding,K08515//SNARE interactions in vesicular transport
6847,112,0,0,0,0,40,0,0,23,0,0,0,SYCP1;synaptonemal complex protein 1,GO:0000801//central element;GO:0000802//transverse filament;GO:0001673//male germ cell nucleus,GO:0032880//regulation of protein localization;GO:0000711//meiotic DNA repair synthesis;GO:0035092//sperm chromatin condensation;GO:0007130//synaptonemal complex assembly;GO:0007131//reciprocal meiotic recombination;GO:0007283//spermatogenesis;GO:0051026//chiasma assembly,GO:0003677//DNA binding,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
6850,0,0,0,0,24,0,48,0,47,0,6,0,SYK;spleen tyrosine kinase,GO:0005829//cytosol;GO:0042101//T cell receptor complex;GO:0005886//plasma membrane;GO:0019815//B cell receptor complex;GO:0032009//early phagosome,GO:0006468//protein phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0010543//regulation of platelet activation;GO:0043366//beta selection;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0090330//regulation of platelet aggregation;GO:0007257//activation of JUN kinase activity;GO:0007229//integrin-mediated signaling pathway;GO:0045425//positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0002366//leukocyte activation involved in immune response;GO:0002283//neutrophil activation involved in immune response;GO:0046777//protein autophosphorylation;GO:0032928//regulation of superoxide anion generation;GO:0048514//blood vessel morphogenesis;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0002281//macrophage activation involved in immune response;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0002554//serotonin secretion by platelet;GO:0002250//adaptive immune response;GO:0030593//neutrophil chemotaxis;GO:0050853//B cell receptor signaling pathway;GO:0019370//leukotriene biosynthetic process;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043313//regulation of neutrophil degranulation;GO:0071226//cellular response to molecule of fungal origin;GO:0050764//regulation of phagocytosis;GO:0045780//positive regulation of bone resorption;GO:0007596//blood coagulation;GO:0045579//positive regulation of B cell differentiation;GO:0070372//regulation of ERK1 and ERK2 cascade;GO:0043306//positive regulation of mast cell degranulation;GO:0030168//platelet activation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0016032//viral process;GO:0045401//positive regulation of interleukin-3 biosynthetic process;GO:0045588//positive regulation of gamma-delta T cell differentiation;GO:0042742//defense response to bacterium;GO:0009887//organ morphogenesis;GO:0001945//lymph vessel development;GO:0007167//enzyme linked receptor protein signaling pathway;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0050715//positive regulation of cytokine secretion;GO:0008283//cell proliferation;GO:0007159//leukocyte cell-cell adhesion;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001525//angiogenesis;GO:0045087//innate immune response;GO:0090237//regulation of arachidonic acid secretion,GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0004713//protein tyrosine kinase activity;GO:0019901//protein kinase binding;GO:0004672//protein kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding,K05855//Osteoclast differentiation;Natural killer cell mediated cytotoxicity;Epstein-Barr virus infection;Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;Tuberculosis;Fc gamma R-mediated phagocytosis;B cell receptor signaling pathway
6853,0,40,4,0,0,10,61,171,32,0,28,0,SYN1;synapsin I,GO:0008021//synaptic vesicle;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0030054//cell junction;GO:0030425//dendrite,GO:0046928//regulation of neurotransmitter secretion;GO:2000300//regulation of synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0008152//metabolic process;GO:0007268//synaptic transmission,GO:0048306//calcium-dependent protein binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005215//transporter activity;GO:0005524//ATP binding;GO:0003824//catalytic activity,-
6854,0,0,0,8,5,0,20,0,28,0,5,0,SYN2;synapsin II,GO:0030054//cell junction;GO:0008021//synaptic vesicle,GO:0007269//neurotransmitter secretion;GO:0008152//metabolic process;GO:0007268//synaptic transmission,GO:0005524//ATP binding;GO:0003824//catalytic activity,-
6855,0,58,0,0,0,0,0,0,0,0,0,0,SYP;synaptophysin,GO:0060076//excitatory synapse;GO:0044306//neuron projection terminus;GO:0048786//presynaptic active zone;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0043005//neuron projection;GO:0043234//protein complex;GO:0030285//integral component of synaptic vesicle membrane,GO:2000474//regulation of opioid receptor signaling pathway;GO:0071310//cellular response to organic substance;GO:0016188//synaptic vesicle maturation;GO:0006897//endocytosis;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0048499//synaptic vesicle membrane organization;GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0048168//regulation of neuronal synaptic plasticity,GO:0032403//protein complex binding;GO:0005215//transporter activity;GO:0042169//SH2 domain binding;GO:0043621//protein self-association;GO:0017075//syntaxin-1 binding;GO:0015485//cholesterol binding;GO:0042802//identical protein binding,-
6856,0,0,0,16,72,0,23,18,12,0,1,0,SYPL1;synaptophysin-like 1,GO:0030285//integral component of synaptic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0042470//melanosome;GO:0030141//secretory granule;GO:0030659//cytoplasmic vesicle membrane,GO:0006810//transport;GO:0007268//synaptic transmission,GO:0005215//transporter activity,-
6857,0,23,0,0,23,13,0,63,27,0,0,0,SYT1;synaptotagmin I,GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0070083//clathrin-sculpted monoamine transport vesicle membrane;GO:0030666//endocytic vesicle membrane;GO:0060201//clathrin-sculpted acetylcholine transport vesicle membrane;GO:0060076//excitatory synapse;GO:0060203//clathrin-sculpted glutamate transport vesicle membrane;GO:0042584//chromaffin granule membrane;GO:0031045//dense core granule;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0030672//synaptic vesicle membrane;GO:0008021//synaptic vesicle;GO:0043005//neuron projection;GO:0016021//integral component of membrane,GO:0014047//glutamate secretion;GO:0017157//regulation of exocytosis;GO:0016079//synaptic vesicle exocytosis;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0031340//positive regulation of vesicle fusion;GO:0051260//protein homooligomerization;GO:0048278//vesicle docking;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0005513//detection of calcium ion,"GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005215//transporter activity;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008022//protein C-terminus binding;GO:0042802//identical protein binding;GO:0017075//syntaxin-1 binding;GO:0005545//1-phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0005516//calmodulin binding",K15290//Synaptic vesicle cycle
686,0,1,0,0,1,0,47,0,4,0,0,3,BTD;biotinidase,GO:0005759//mitochondrial matrix;GO:0045177//apical part of cell;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0043204//perikaryon;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0007417//central nervous system development;GO:0006766//vitamin metabolic process;GO:0006768//biotin metabolic process;GO:0008544//epidermis development,GO:0047708//biotinidase activity;GO:0004075//biotin carboxylase activity,K01435//Biotin metabolism;Metabolic pathways;Vitamin digestion and absorption
6860,0,0,0,0,0,0,32,0,12,0,0,0,SYT4;synaptotagmin IV,GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0030672//synaptic vesicle membrane;GO:0031045//dense core granule;GO:0030054//cell junction,GO:0006887//exocytosis;GO:0031339//negative regulation of vesicle fusion;GO:0045955//negative regulation of calcium ion-dependent exocytosis;GO:0007269//neurotransmitter secretion,GO:0005215//transporter activity;GO:0030276//clathrin binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding;GO:0000149//SNARE binding,K15290//Synaptic vesicle cycle
6862,9,0,0,0,0,11,21,4,56,64,5,425,"T;T, brachyury homolog (mouse)",GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008595//anterior/posterior axis specification, embryo;GO:0048706//embryonic skeletal system development;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0007341//penetration of zona pellucida;GO:0014028//notochord formation;GO:0003007//heart morphogenesis;GO:0007165//signal transduction;GO:0001843//neural tube closure;GO:0060349//bone morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0001839//neural plate morphogenesis;GO:0007509//mesoderm migration involved in gastrulation;GO:0060395//SMAD protein signal transduction;GO:0090009//primitive streak formation;GO:0008284//positive regulation of cell proliferation;GO:0001756//somitogenesis;GO:0061371//determination of heart left/right asymmetry;GO:0036342//post-anal tail morphogenesis;GO:0001570//vasculogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0030509//BMP signaling pathway;GO:0007498//mesoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0023019//signal transduction involved in regulation of gene expression",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0001085//RNA polymerase II transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6865,28,0,0,0,19,8,39,0,16,0,33,0,TACR2;tachykinin receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0035106//operant conditioning;GO:0070459//prolactin secretion;GO:0043117//positive regulation of vascular permeability;GO:0014827//intestine smooth muscle contraction;GO:0007588//excretion;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0007217//tachykinin receptor signaling pathway;GO:0033685//negative regulation of luteinizing hormone secretion;GO:0006936//muscle contraction;GO:0014057//positive regulation of acetylcholine secretion, neurotransmission",GO:0016497//substance K receptor activity;GO:0005515//protein binding;GO:0004995//tachykinin receptor activity,K04223//Calcium signaling pathway;Neuroactive ligand-receptor interaction
6866,0,0,0,0,0,0,0,0,6,87,7,0,TAC3;tachykinin 3,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0007218//neuropeptide signaling pathway;GO:0007217//tachykinin receptor signaling pathway;GO:0007565//female pregnancy,GO:0005515//protein binding;GO:0005102//receptor binding,-
6867,0,0,0,17,112,0,0,0,22,0,16,0,"TACC1;transforming, acidic coiled-coil containing protein 1",GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045111//intermediate filament cytoskeleton,GO:0007049//cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0032886//regulation of microtubule-based process;GO:0051301//cell division;GO:0022008//neurogenesis;GO:0022027//interkinetic nuclear migration;GO:0021987//cerebral cortex development,GO:0005515//protein binding;GO:0019904//protein domain specific binding,-
6868,0,0,0,69,127,0,6,0,32,107,71,0,ADAM17;ADAM metallopeptidase domain 17,GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0009986//cell surface;GO:0016020//membrane;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane,"GO:0055099//response to high density lipoprotein particle;GO:0042493//response to drug;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0007220//Notch receptor processing;GO:0030335//positive regulation of cell migration;GO:0031659//positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle;GO:0033025//regulation of mast cell apoptotic process;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0006509//membrane protein ectodomain proteolysis;GO:0032717//negative regulation of interleukin-8 production;GO:0007219//Notch signaling pathway;GO:0035313//wound healing, spreading of epidermal cells;GO:0002446//neutrophil mediated immunity;GO:0030183//B cell differentiation;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0031293//membrane protein intracellular domain proteolysis;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0048536//spleen development;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0002690//positive regulation of leukocyte chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0032722//positive regulation of chemokine production;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0033627//cell adhesion mediated by integrin;GO:0051272//positive regulation of cellular component movement;GO:0030307//positive regulation of cell growth;GO:0002467//germinal center formation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035625//epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway;GO:0007155//cell adhesion;GO:0097190//apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0048870//cell motility;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0033077//T cell differentiation in thymus;GO:0030574//collagen catabolic process;GO:0010820//positive regulation of T cell chemotaxis",GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0005112//Notch binding;GO:0005138//interleukin-6 receptor binding;GO:0017124//SH3 domain binding,K06059//Alzheimer's disease;Epithelial cell signaling in Helicobacter pylori infection;Notch signaling pathway
6869,8,0,0,0,0,43,17,0,23,0,9,0,TACR1;tachykinin receptor 1,GO:0005887//integral component of plasma membrane;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0030425//dendrite;GO:0005886//plasma membrane,"GO:0060083//smooth muscle contraction involved in micturition;GO:0043117//positive regulation of vascular permeability;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0048660//regulation of smooth muscle cell proliferation;GO:0009408//response to heat;GO:0046887//positive regulation of hormone secretion;GO:0010996//response to auditory stimulus;GO:0045777//positive regulation of blood pressure;GO:0045471//response to ethanol;GO:0007616//long-term memory;GO:0051496//positive regulation of stress fiber assembly;GO:0002118//aggressive behavior;GO:0035106//operant conditioning;GO:0006954//inflammatory response;GO:0046878//positive regulation of saliva secretion;GO:0014910//regulation of smooth muscle cell migration;GO:0043278//response to morphine;GO:0032570//response to progesterone;GO:0010634//positive regulation of epithelial cell migration;GO:0045778//positive regulation of ossification;GO:0010193//response to ozone;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0002687//positive regulation of leukocyte migration;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0007217//tachykinin receptor signaling pathway;GO:0035815//positive regulation of renal sodium excretion;GO:0009582//detection of abiotic stimulus;GO:0048266//behavioral response to pain;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008306//associative learning;GO:0042713//sperm ejaculation;GO:0002526//acute inflammatory response;GO:0035094//response to nicotine;GO:0032224//positive regulation of synaptic transmission, cholinergic;GO:0032355//response to estradiol;GO:0042755//eating behavior;GO:0003051//angiotensin-mediated drinking behavior;GO:0045760//positive regulation of action potential;GO:0045907//positive regulation of vasoconstriction;GO:0050671//positive regulation of lymphocyte proliferation",GO:0005515//protein binding;GO:0004995//tachykinin receptor activity;GO:0016496//substance P receptor activity,K04222//Calcium signaling pathway;Measles;Neuroactive ligand-receptor interaction
687,0,76,89,125,350,15,76,0,13,10,316,0,KLF9;Kruppel-like factor 9,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0007566//embryo implantation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0097067//cellular response to thyroid hormone stimulus;GO:0050847//progesterone receptor signaling pathway;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
6870,0,0,0,0,0,9,0,0,7,0,0,0,TACR3;tachykinin receptor 3,GO:0032809//neuronal cell body membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0032590//dendrite membrane;GO:0005634//nucleus,GO:0060259//regulation of feeding behavior;GO:0010460//positive regulation of heart rate;GO:0043278//response to morphine;GO:0007568//aging;GO:0042220//response to cocaine;GO:0032355//response to estradiol;GO:0070474//positive regulation of uterine smooth muscle contraction;GO:0007217//tachykinin receptor signaling pathway;GO:0042053//regulation of dopamine metabolic process;GO:0042538//hyperosmotic salinity response;GO:0045777//positive regulation of blood pressure,GO:0005515//protein binding;GO:0004995//tachykinin receptor activity,K04224//Calcium signaling pathway;Neuroactive ligand-receptor interaction
6871,0,0,0,0,15,14,15,0,30,157,0,0,TADA2A;transcriptional adaptor 2A,GO:0000125//PCAF complex;GO:0005634//nucleus;GO:0005694//chromosome,"GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0004402//histone acetyltransferase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0003712//transcription cofactor activity,-
6872,0,1,0,26,65,0,135,51,88,111,6,83,"TAF1;TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa",GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0051123//RNA polymerase II transcriptional preinitiation complex assembly;GO:0006352//DNA-templated transcription, initiation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0000117//regulation of transcription involved in G2/M transition of mitotic cell cycle;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0016032//viral process;GO:0006974//cellular response to DNA damage stimulus;GO:0016573//histone acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046777//protein autophosphorylation;GO:0018105//peptidyl-serine phosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0018107//peptidyl-threonine phosphorylation",GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0070577//lysine-acetylated histone binding;GO:0002039//p53 binding;GO:0004402//histone acetyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0017025//TBP-class protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0004674//protein serine/threonine kinase activity;GO:0008134//transcription factor binding;GO:0005515//protein binding,K03125//Basal transcription factors
6873,0,33,0,8,26,6,48,0,25,162,0,0,"TAF2;TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa",GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex,GO:0000086//G2/M transition of mitotic cell cycle;GO:0006508//proteolysis;GO:0014070//response to organic cyclic compound;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0044212//transcription regulatory region DNA binding,K03128//Basal transcription factors
6874,105,0,0,0,0,0,12,59,30,0,0,0,"TAF4;TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa",GO:0005654//nucleoplasm;GO:0071339//MLL1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005669//transcription factor TFIID complex;GO:0033276//transcription factor TFTC complex;GO:0005730//nucleolus,"GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001541//ovarian follicle development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression",GO:0003713//transcription coactivator activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding,K03129//Basal transcription factors;Herpes simplex infection;Huntington's disease
6875,45,0,0,0,1,30,0,0,28,0,0,0,"TAF4B;TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa",GO:0005730//nucleolus;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression",GO:0051059//NF-kappaB binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity,K03129//Herpes simplex infection;Basal transcription factors;Huntington's disease
6876,0,0,0,0,0,0,0,0,6,0,9,0,TAGLN;transgelin,GO:0005737//cytoplasm,GO:0007517//muscle organ development;GO:0030855//epithelial cell differentiation,GO:0005515//protein binding;GO:0003779//actin binding,K05730//Regulation of actin cytoskeleton;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Focal adhesion;Fc epsilon RI signaling pathway;Chemokine signaling pathway;Leukocyte transendothelial migration;B cell receptor signaling pathway;Fc gamma R-mediated phagocytosis
6877,0,178,1,56,64,0,0,70,29,0,0,0,"TAF5;TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0033276//transcription factor TFTC complex;GO:0005730//nucleolus,"GO:0016573//histone acetylation;GO:0006352//DNA-templated transcription, initiation;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression",GO:0044212//transcription regulatory region DNA binding;GO:0046983//protein dimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0004402//histone acetyltransferase activity,K03130//Herpes simplex infection;Basal transcription factors
6878,0,76,1,53,81,0,0,100,9,198,121,0,"TAF6;TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa",GO:0033276//transcription factor TFTC complex;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm,"GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045786//negative regulation of cell cycle;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity;GO:0006352//DNA-templated transcription, initiation",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K03131//Herpes simplex infection;Basal transcription factors
6879,0,1,0,10,52,0,0,0,15,0,0,0,"TAF7;TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa",GO:0033276//transcription factor TFTC complex;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005669//transcription factor TFIID complex;GO:0005634//nucleus;GO:0071339//MLL1 complex;GO:0008024//positive transcription elongation factor complex b,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006469//negative regulation of protein kinase activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000296//spermine transport;GO:0006366//transcription from RNA polymerase II promoter;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0035067//negative regulation of histone acetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0035035//histone acetyltransferase binding;GO:0008134//transcription factor binding;GO:0042809//vitamin D receptor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding,K03132//Basal transcription factors
688,62,0,0,8,37,9,0,0,34,0,0,0,KLF5;Kruppel-like factor 5 (intestinal),GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071407//cellular response to organic cyclic compound;GO:0032534//regulation of microvillus assembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060576//intestinal epithelial cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0030033//microvillus assembly;GO:0035914//skeletal muscle cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:1901653//cellular response to peptide;GO:0008284//positive regulation of cell proliferation,GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
6880,0,0,0,28,46,0,0,0,9,0,0,0,"TAF9;TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa",GO:0005669//transcription factor TFIID complex;GO:0070761//pre-snoRNP complex;GO:0033276//transcription factor TFTC complex;GO:0071339//MLL1 complex;GO:0000125//PCAF complex;GO:0030914//STAGA complex;GO:0005654//nucleoplasm,GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0050821//protein stabilization;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006325//chromatin organization;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030307//positive regulation of cell growth;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043966//histone H3 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus;GO:0060760//positive regulation of response to cytokine stimulus;GO:0016032//viral process;GO:0070555//response to interleukin-1;GO:0006366//transcription from RNA polymerase II promoter,GO:0070742//C2H2 zinc finger domain binding;GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0033613//activating transcription factor binding;GO:0003677//DNA binding;GO:0002039//p53 binding;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K14535//Ribosome biogenesis in eukaryotes;Basal transcription factors
6881,0,0,0,23,32,0,0,0,23,0,16,0,"TAF10;TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa",GO:0033276//transcription factor TFTC complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030914//STAGA complex;GO:0000125//PCAF complex;GO:0005669//transcription factor TFIID complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0051260//protein homooligomerization;GO:0006352//DNA-templated transcription, initiation;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0016578//histone deubiquitination;GO:0010467//gene expression",GO:0030331//estrogen receptor binding;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0070063//RNA polymerase binding;GO:0019899//enzyme binding,K03134//Basal transcription factors;Herpes simplex infection
6882,0,1,1,17,0,15,0,0,76,0,0,0,"TAF11;TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa",GO:0005669//transcription factor TFIID complex;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0043923//positive regulation by host of viral transcription;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0042809//vitamin D receptor binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0047485//protein N-terminus binding,K03135//Basal transcription factors
6883,0,0,0,0,33,0,11,0,11,0,14,0,"TAF12;TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa",GO:0005654//nucleoplasm;GO:0030914//STAGA complex;GO:0000125//PCAF complex;GO:0033276//transcription factor TFTC complex;GO:0005669//transcription factor TFIID complex,"GO:0006325//chromatin organization;GO:2001141//regulation of RNA biosynthetic process;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043966//histone H3 acetylation;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation",GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity,K03126//Basal transcription factors
6884,0,0,1,39,77,0,0,0,0,0,1,0,"TAF13;TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa",GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006352//DNA-templated transcription, initiation;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0008022//protein C-terminus binding,K03127//Basal transcription factors;Herpes simplex infection
6885,0,2,0,6,50,0,20,0,41,0,0,0,MAP3K7;mitogen-activated protein kinase kinase kinase 7,GO:0005737//cytoplasm;GO:0008385//IkappaB kinase complex;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0005634//nucleus;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,"GO:0002726//positive regulation of T cell cytokine production;GO:0000187//activation of MAPK activity;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0001841//neural tube formation;GO:2000377//regulation of reactive oxygen species metabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043507//positive regulation of JUN kinase activity;GO:0006915//apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0043966//histone H3 acetylation;GO:0006351//transcription, DNA-templated;GO:0000186//activation of MAPKK activity;GO:0046330//positive regulation of JNK cascade;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0050870//positive regulation of T cell activation;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007254//JNK cascade;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0001525//angiogenesis;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0032743//positive regulation of interleukin-2 production;GO:0050852//T cell receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034162//toll-like receptor 9 signaling pathway;GO:0007252//I-kappaB phosphorylation;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway",GO:0004672//protein kinase activity;GO:0004708//MAP kinase kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0097110//scaffold protein binding;GO:0000287//magnesium ion binding;GO:0004709//MAP kinase kinase kinase activity,K04427//Toll-like receptor signaling pathway;NOD-like receptor signaling pathway;NF-kappa B signaling pathway;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Adherens junction;Measles;Wnt signaling pathway;MAPK signaling pathway;Herpes simplex infection;Osteoclast differentiation;Toxoplasmosis;Leishmaniasis;T cell receptor signaling pathway
6886,0,0,0,0,0,0,81,0,10,0,67,0,TAL1;T-cell acute lymphocytic leukemia 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0033193//Lsd1/2 complex;GO:0000118//histone deacetylase complex,"GO:0021527//spinal cord association neuron differentiation;GO:0045799//positive regulation of chromatin assembly or disassembly;GO:2000036//regulation of stem cell maintenance;GO:0030097//hemopoiesis;GO:0035162//embryonic hemopoiesis;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030220//platelet formation;GO:0060218//hematopoietic stem cell differentiation;GO:0060375//regulation of mast cell differentiation;GO:0060216//definitive hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0060018//astrocyte fate commitment;GO:0051781//positive regulation of cell division;GO:0060217//hemangioblast cell differentiation;GO:0035855//megakaryocyte development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030219//megakaryocyte differentiation;GO:0045648//positive regulation of erythrocyte differentiation;GO:0001525//angiogenesis;GO:0030221//basophil differentiation;GO:0031334//positive regulation of protein complex assembly;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007626//locomotory behavior;GO:0045931//positive regulation of mitotic cell cycle;GO:0043249//erythrocyte maturation;GO:0030218//erythrocyte differentiation",GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0070888//E-box binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0042826//histone deacetylase binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding,-
6887,0,0,0,0,0,0,0,0,9,0,5,0,TAL2;T-cell acute lymphocytic leukemia 2,-,"GO:0030901//midbrain development;GO:0006351//transcription, DNA-templated;GO:0035264//multicellular organism growth;GO:0021794//thalamus development;GO:0006355//regulation of transcription, DNA-templated;GO:0009791//post-embryonic development",GO:0046983//protein dimerization activity;GO:0003677//DNA binding,-
6888,0,3,0,17,52,0,41,0,16,105,0,0,TALDO1;transaldolase 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0005999//xylulose biosynthetic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0019682//glyceraldehyde-3-phosphate metabolic process;GO:0006112//energy reserve metabolic process;GO:0006098//pentose-phosphate shunt",GO:0004801//sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity;GO:0048029//monosaccharide binding,K00616//Other glycan degradation;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Biosynthesis of secondary metabolites
689,0,129,1,69,216,0,0,0,20,0,0,0,BTF3;basic transcription factor 3,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001701//in utero embryonic development;GO:0006366//transcription from RNA polymerase II promoter;GO:0015031//protein transport;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
6890,0,0,0,0,0,0,0,0,8,0,0,0,"TAP1;transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042825//TAP complex;GO:0005789//endoplasmic reticulum membrane,"GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006952//defense response;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0006200//ATP catabolic process;GO:0015833//peptide transport;GO:0019060//intracellular transport of viral protein in host cell;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0046967//cytosol to ER transport;GO:0055085//transmembrane transport","GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046979//TAP2 binding;GO:0043531//ADP binding;GO:0023029//MHC class Ib protein binding;GO:0042605//peptide antigen binding;GO:0015197//peptide transporter activity;GO:0005524//ATP binding;GO:0042288//MHC class I protein binding;GO:0046978//TAP1 binding",K05653//Primary immunodeficiency;Herpes simplex infection;ABC transporters;Phagosome;Antigen processing and presentation
6891,0,0,0,0,0,0,0,0,5,0,0,0,"TAP2;transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0042825//TAP complex,"GO:0055085//transmembrane transport;GO:0002489//antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent;GO:0046967//cytosol to ER transport;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0046968//peptide antigen transport;GO:0019060//intracellular transport of viral protein in host cell;GO:0002591//positive regulation of antigen processing and presentation of peptide antigen via MHC class I;GO:0002481//antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent;GO:0006200//ATP catabolic process;GO:0002485//antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I",GO:0005515//protein binding;GO:0015433//peptide antigen-transporting ATPase activity;GO:0005215//transporter activity;GO:0046980//tapasin binding;GO:0023029//MHC class Ib protein binding;GO:0046978//TAP1 binding;GO:0005524//ATP binding;GO:0015197//peptide transporter activity,K05654//Phagosome;ABC transporters;Herpes simplex infection;Primary immunodeficiency;Antigen processing and presentation
6892,0,7,0,2,9,0,13,4,2,0,6,0,TAPBP;TAP binding protein (tapasin),GO:0005789//endoplasmic reticulum membrane;GO:0042825//TAP complex;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0042824//MHC class I peptide loading complex;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,"GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0015833//peptide transport;GO:0006955//immune response;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0050823//peptide antigen stabilization;GO:0006461//protein complex assembly;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0019885//antigen processing and presentation of endogenous peptide antigen via MHC class I;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I",GO:0005515//protein binding;GO:0042605//peptide antigen binding;GO:0051082//unfolded protein binding;GO:0046978//TAP1 binding;GO:0015433//peptide antigen-transporting ATPase activity;GO:0042288//MHC class I protein binding;GO:0046979//TAP2 binding,K08058//Antigen processing and presentation
6894,0,0,0,15,23,2,17,0,21,6,0,0,TARBP1;TAR (HIV-1) RNA binding protein 1,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006396//RNA processing;GO:0001510//RNA methylation,GO:0008173//RNA methyltransferase activity;GO:0003723//RNA binding,K03239//RNA transport;Cysteine and methionine metabolism;Metabolic pathways
6895,0,28,0,23,19,0,30,45,11,0,4,0,TARBP2;TAR (HIV-1) RNA binding protein 2,GO:0005829//cytosol;GO:0016442//RISC complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045070//positive regulation of viral genome replication;GO:0030423//targeting of mRNA for destruction involved in RNA interference;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050689//negative regulation of defense response to virus by host;GO:0006355//regulation of transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0046782//regulation of viral transcription;GO:0030422//production of siRNA involved in RNA interference;GO:0010467//gene expression;GO:0035280//miRNA loading onto RISC involved in gene silencing by miRNA;GO:0006417//regulation of translation;GO:0031054//pre-miRNA processing",GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0035197//siRNA binding;GO:0035198//miRNA binding;GO:0003725//double-stranded RNA binding,-
6897,0,71,1,55,148,0,0,156,86,0,0,0,TARS;threonyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006435//threonyl-tRNA aminoacylation;GO:0006412//translation,GO:0004829//threonine-tRNA ligase activity;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding,K01868//Aminoacyl-tRNA biosynthesis;Vitamin B6 metabolism;Metabolic pathways
6898,0,0,0,0,0,11,0,0,40,0,1,0,TAT;tyrosine aminotransferase,GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0006103//2-oxoglutarate metabolic process;GO:0006559//L-phenylalanine catabolic process;GO:0009058//biosynthetic process;GO:0006979//response to oxidative stress;GO:0034641//cellular nitrogen compound metabolic process;GO:0006536//glutamate metabolic process;GO:0046689//response to mercury ion;GO:0006572//tyrosine catabolic process,GO:0004838//L-tyrosine:2-oxoglutarate aminotransferase activity;GO:0016597//amino acid binding;GO:0030170//pyridoxal phosphate binding;GO:0080130//L-phenylalanine:2-oxoglutarate aminotransferase activity,"K00815//Biosynthesis of secondary metabolites;Cysteine and methionine metabolism;Isoquinoline alkaloid biosynthesis;Phenylalanine, tyrosine and tryptophan biosynthesis;Ubiquinone and other terpenoid-quinone biosynthesis;Phenylalanine metabolism;Tyrosine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;Metabolic pathways"
6899,0,0,0,0,9,0,18,171,19,0,0,0,TBX1;T-box 1,GO:0005634//nucleus,"GO:0060325//face morphogenesis;GO:0071600//otic vesicle morphogenesis;GO:0007389//pattern specification process;GO:0007498//mesoderm development;GO:0021644//vagus nerve morphogenesis;GO:0042693//muscle cell fate commitment;GO:0042473//outer ear morphogenesis;GO:0048752//semicircular canal morphogenesis;GO:0001974//blood vessel remodeling;GO:0060037//pharyngeal system development;GO:0007605//sensory perception of sound;GO:0001708//cell fate specification;GO:0048644//muscle organ morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048538//thymus development;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:2001037//positive regulation of tongue muscle cell differentiation;GO:0045596//negative regulation of cell differentiation;GO:0060017//parathyroid gland development;GO:0030878//thyroid gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048514//blood vessel morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0050679//positive regulation of epithelial cell proliferation;GO:0008283//cell proliferation;GO:0060415//muscle tissue morphogenesis;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:0001945//lymph vessel development;GO:0006351//transcription, DNA-templated;GO:0048703//embryonic viscerocranium morphogenesis;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0070166//enamel mineralization;GO:0007507//heart development;GO:0001568//blood vessel development;GO:0001525//angiogenesis;GO:0042472//inner ear morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0048384//retinoic acid receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0030855//epithelial cell differentiation;GO:0001934//positive regulation of protein phosphorylation;GO:0007517//muscle organ development;GO:0042471//ear morphogenesis;GO:0001755//neural crest cell migration;GO:0060023//soft palate development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0035176//social behavior;GO:0071300//cellular response to retinoic acid;GO:0043587//tongue morphogenesis;GO:0048844//artery morphogenesis;GO:0090103//cochlea morphogenesis;GO:0003007//heart morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007368//determination of left/right symmetry;GO:0035909//aorta morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0042474//middle ear morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0009952//anterior/posterior pattern specification",GO:0046983//protein dimerization activity;GO:0043565//sequence-specific DNA binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
6900,0,0,1,0,4,57,43,52,39,0,0,0,CNTN2;contactin 2 (axonal),GO:0005886//plasma membrane;GO:0045202//synapse;GO:0009986//cell surface;GO:0044224//juxtaparanode region of axon;GO:0043025//neuronal cell body;GO:0033268//node of Ranvier;GO:0031225//anchored component of membrane;GO:0043209//myelin sheath;GO:0008076//voltage-gated potassium channel complex;GO:0005887//integral component of plasma membrane,GO:0031623//receptor internalization;GO:0022010//central nervous system myelination;GO:0048710//regulation of astrocyte differentiation;GO:0000226//microtubule cytoskeleton organization;GO:0031133//regulation of axon diameter;GO:0007155//cell adhesion;GO:0071206//establishment of protein localization to juxtaparanode region of axon;GO:0034613//cellular protein localization;GO:0021853//cerebral cortex GABAergic interneuron migration;GO:0007413//axonal fasciculation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0045163//clustering of voltage-gated potassium channels;GO:0097090//presynaptic membrane organization;GO:0007411//axon guidance;GO:0060168//positive regulation of adenosine receptor signaling pathway;GO:0007612//learning;GO:0007628//adult walking behavior;GO:0010954//positive regulation of protein processing;GO:0045665//negative regulation of neuron differentiation,GO:0001948//glycoprotein binding;GO:0042802//identical protein binding;GO:0030246//carbohydrate binding;GO:0043621//protein self-association,K06760//Cell adhesion molecules (CAMs)
6901,0,102,10,20,70,0,0,137,42,0,88,0,TAZ;tafazzin,GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,GO:0007519//skeletal muscle tissue development;GO:0030097//hemopoiesis;GO:0035965//cardiolipin acyl-chain remodeling;GO:0006936//muscle contraction;GO:0032049//cardiolipin biosynthetic process;GO:0042775//mitochondrial ATP synthesis coupled electron transport;GO:0042407//cristae formation;GO:0048738//cardiac muscle tissue development;GO:0046474//glycerophospholipid biosynthetic process;GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0060048//cardiac muscle contraction;GO:0006644//phospholipid metabolic process;GO:0007507//heart development;GO:0044281//small molecule metabolic process,GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity,K13511//Glycerophospholipid metabolism
6903,0,36,0,6,2,0,0,0,0,0,0,0,TBCC;tubulin folding cofactor C,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium,GO:0007023//post-chaperonin tubulin folding pathway;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0006184//GTP catabolic process;GO:0000902//cell morphogenesis;GO:0044267//cellular protein metabolic process,GO:0051087//chaperone binding;GO:0003924//GTPase activity,K06641//HTLV-I infection;p53 signaling pathway;Cell cycle - yeast;Cell cycle;K11447//Transcriptional misregulation in cancer
6904,0,1,0,0,34,70,0,0,68,0,5,0,TBCD;tubulin folding cofactor D,GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0016328//lateral plasma membrane;GO:0005874//microtubule;GO:0005923//tight junction,GO:0070830//tight junction assembly;GO:0043547//positive regulation of GTPase activity;GO:0051084//'de novo' posttranslational protein folding;GO:0031115//negative regulation of microtubule polymerization;GO:0044267//cellular protein metabolic process;GO:0010812//negative regulation of cell-substrate adhesion;GO:0034333//adherens junction assembly;GO:0006457//protein folding;GO:0007023//post-chaperonin tubulin folding pathway,GO:0005515//protein binding;GO:0048487//beta-tubulin binding;GO:0005096//GTPase activator activity;GO:0051087//chaperone binding,K12864//Spliceosome
6905,0,1,91,96,279,23,36,0,40,0,84,0,TBCE;tubulin folding cofactor E,GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0051084//'de novo' posttranslational protein folding;GO:0008344//adult locomotory behavior;GO:0009791//post-embryonic development;GO:0048589//developmental growth;GO:0007023//post-chaperonin tubulin folding pathway;GO:0006457//protein folding;GO:0000226//microtubule cytoskeleton organization;GO:0044267//cellular protein metabolic process;GO:0014889//muscle atrophy;GO:0048936//peripheral nervous system neuron axonogenesis,GO:0051087//chaperone binding,K10411//Huntington's disease;K08844//Parkinson's disease;K10168//Salmonella infection;Toll-like receptor signaling pathway;Pathogenic Escherichia coli infection;Legionellosis;K04648//Huntington's disease;Vasopressin-regulated water reabsorption;K02971//Ribosome
6906,0,0,0,0,0,0,0,0,7,0,0,0,"SERPINA7;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0051412//response to corticosterone;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis;GO:0070327//thyroid hormone transport;GO:0043434//response to peptide hormone;GO:0034695//response to prostaglandin E;GO:0042493//response to drug;GO:0007568//aging;GO:0009791//post-embryonic development;GO:0033189//response to vitamin A,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0042562//hormone binding,K03984//Complement and coagulation cascades
6907,0,54,0,38,64,13,18,0,94,0,8,0,TBL1X;transducin (beta)-like 1X-linked,GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0005654//nucleoplasm;GO:0017053//transcriptional repressor complex;GO:0000118//histone deacetylase complex,"GO:0006508//proteolysis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0060070//canonical Wnt signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0044281//small molecule metabolic process;GO:0007219//Notch signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007605//sensory perception of sound",GO:0003714//transcription corepressor activity;GO:0008013//beta-catenin binding;GO:0019904//protein domain specific binding;GO:0008022//protein C-terminus binding;GO:0044212//transcription regulatory region DNA binding;GO:0008134//transcription factor binding;GO:0042393//histone binding;GO:0005515//protein binding,K04508//Wnt signaling pathway
6908,0,0,0,6,9,15,0,0,17,0,4,0,TBP;TATA box binding protein,GO:0005719//nuclear euchromatin;GO:0005672//transcription factor TFIIA complex;GO:0005669//transcription factor TFIID complex;GO:0001940//male pronucleus;GO:0001939//female pronucleus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0007283//spermatogenesis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0016032//viral process;GO:0006360//transcription from RNA polymerase I promoter;GO:0008219//cell death;GO:0006368//transcription elongation from RNA polymerase II promoter",GO:0008134//transcription factor binding;GO:0070491//repressing transcription factor binding;GO:0005515//protein binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0044212//transcription regulatory region DNA binding,K03120//Epstein-Barr virus infection;Basal transcription factors;Herpes simplex infection;HTLV-I infection;Huntington's disease
6909,0,48,0,19,31,0,0,82,9,0,25,0,TBX2;T-box 2,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0060021//palate development;GO:0048738//cardiac muscle tissue development;GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042733//embryonic digit morphogenesis;GO:0006351//transcription, DNA-templated;GO:0036302//atrioventricular canal development;GO:0003256//regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0060560//developmental growth involved in morphogenesis;GO:0060596//mammary placode formation;GO:1901208//negative regulation of heart looping;GO:0090398//cellular senescence;GO:0008284//positive regulation of cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:1901211//negative regulation of cardiac chamber formation;GO:0060465//pharynx development;GO:0007521//muscle cell fate determination;GO:0007569//cell aging;GO:0045892//negative regulation of transcription, DNA-templated;GO:0048596//embryonic camera-type eye morphogenesis;GO:0003148//outflow tract septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0035909//aorta morphogenesis",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
6910,0,0,0,0,2,0,0,0,61,76,1,0,TBX5;T-box 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0002009//morphogenesis of an epithelium;GO:0072513//positive regulation of secondary heart field cardioblast proliferation;GO:1900117//regulation of execution phase of apoptosis;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0007389//pattern specification process;GO:0003197//endocardial cushion development;GO:0030336//negative regulation of cell migration;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0030326//embryonic limb morphogenesis;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0003229//ventricular cardiac muscle tissue development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0060980//cell migration involved in coronary vasculogenesis;GO:0007507//heart development;GO:0060413//atrial septum morphogenesis;GO:0055007//cardiac muscle cell differentiation;GO:0003218//cardiac left ventricle formation;GO:0035115//embryonic forelimb morphogenesis;GO:0003166//bundle of His development;GO:0030262//apoptotic nuclear changes;GO:0035136//forelimb morphogenesis;GO:0030324//lung development;GO:0051891//positive regulation of cardioblast differentiation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0003181//atrioventricular valve morphogenesis;GO:0060039//pericardium development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003281//ventricular septum development",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6911,0,1,0,0,0,31,0,0,78,0,6,0,TBX6;T-box 6,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0023019//signal transduction involved in regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0014043//negative regulation of neuron maturation;GO:0009653//anatomical structure morphogenesis;GO:0010977//negative regulation of neuron projection development;GO:0001707//mesoderm formation;GO:0001708//cell fate specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032525//somite rostral/caudal axis specification",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6915,0,0,0,0,0,0,19,0,13,0,0,0,TBXA2R;thromboxane A2 receptor,GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0045907//positive regulation of vasoconstriction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045777//positive regulation of blood pressure;GO:0007596//blood coagulation;GO:0007584//response to nutrient;GO:0032496//response to lipopolysaccharide;GO:0019932//second-messenger-mediated signaling;GO:0030168//platelet activation;GO:0043547//positive regulation of GTPase activity;GO:0038193//thromboxane A2 signaling pathway;GO:0042493//response to drug;GO:0045987//positive regulation of smooth muscle contraction;GO:0045766//positive regulation of angiogenesis;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0006954//inflammatory response,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0004961//thromboxane A2 receptor activity;GO:0005515//protein binding,K04264//Neuroactive ligand-receptor interaction;Calcium signaling pathway
6916,0,0,0,0,0,0,0,0,14,1,15,0,TBXAS1;thromboxane A synthase 1 (platelet),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0045907//positive regulation of vasoconstriction;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0019371//cyclooxygenase pathway;GO:0055114//oxidation-reduction process;GO:0030644//cellular chloride ion homeostasis;GO:0019369//arachidonic acid metabolic process,"GO:0020037//heme binding;GO:0004796//thromboxane-A synthase activity;GO:0004497//monooxygenase activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0005506//iron ion binding",K01832//Arachidonic acid metabolism;Metabolic pathways
6917,1,32,0,35,93,0,0,0,25,0,13,0,"TCEA1;transcription elongation factor A (SII), 1",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0006283//transcription-coupled nucleotide-excision repair;GO:0010467//gene expression;GO:0006366//transcription from RNA polymerase II promoter;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006289//nucleotide-excision repair;GO:0050434//positive regulation of viral transcription;GO:0006281//DNA repair;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030218//erythrocyte differentiation;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
6919,0,0,1,0,0,19,2,0,0,0,0,0,"TCEA2;transcription elongation factor A (SII), 2",GO:0005813//centrosome;GO:0005634//nucleus;GO:0008023//transcription elongation factor complex;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032784//regulation of DNA-templated transcription, elongation",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
6920,2,1,0,16,56,8,0,2,65,0,0,0,"TCEA3;transcription elongation factor A (SII), 3",GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032784//regulation of DNA-templated transcription, elongation;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
692058,0,0,0,0,0,0,0,0,16,0,0,0,"SNORD11;small nucleolar RNA, C/D box 11",-,-,-,-
692094,0,178,126,142,257,0,0,108,0,0,438,0,"MSMP;microseminoprotein, prostate associated",GO:0005615//extracellular space;GO:0005737//cytoplasm,-,-,-
692099,83,0,0,0,0,0,0,0,0,0,0,0,"FAM86DP;family with sequence similarity 86, member D, pseudogene",-,-,-,K03842//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
6921,0,0,0,1,36,4,9,0,0,0,0,0,"TCEB1;transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)",GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression,GO:0005515//protein binding,K03872//Renal cell carcinoma;Ubiquitin mediated proteolysis;Pathways in cancer
692107,0,0,0,0,0,0,0,0,19,0,0,0,"SNORD66;small nucleolar RNA, C/D box 66",-,-,-,-
692110,0,0,0,0,0,0,24,0,0,0,0,0,"SNORD70;small nucleolar RNA, C/D box 70",-,-,-,-
692158,0,0,0,0,0,17,0,0,0,0,0,0,"SNORA57;small nucleolar RNA, H/ACA box 57",-,-,-,-
692214,0,0,0,0,0,0,0,0,15,0,0,0,"SNORD111;small nucleolar RNA, C/D box 111",-,-,-,-
692225,0,0,0,0,0,0,19,0,0,0,0,0,"SNORD94;small nucleolar RNA, C/D box 94",-,-,-,-
692227,0,0,0,0,0,1,0,0,0,0,0,0,"SNORD104;small nucleolar RNA, C/D box 104",-,-,-,-
6923,0,67,0,0,0,0,0,0,25,0,0,0,"TCEB2;transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)",GO:0005654//nucleoplasm;GO:0070449//elongin complex;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0031462//Cul2-RING ubiquitin ligase complex,GO:0010467//gene expression;GO:0016567//protein ubiquitination;GO:0006366//transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006461//protein complex assembly,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K03873//Pathways in cancer;Ubiquitin mediated proteolysis;Renal cell carcinoma
6924,67,42,2,96,304,16,16,0,29,0,73,2,"TCEB3;transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)",GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005654//nucleoplasm,GO:0050434//positive regulation of viral transcription;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter,GO:0003677//DNA binding,-
6925,56,0,19,3,36,18,102,167,104,55,13,0,TCF4;transcription factor 4,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0045666//positive regulation of neuron differentiation;GO:0065004//protein-DNA complex assembly;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation",GO:0003677//DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001011//sequence-specific DNA binding RNA polymerase recruiting transcription factor activity;GO:0070888//E-box binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001087//TFIIB-class binding transcription factor activity;GO:0008022//protein C-terminus binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001093//TFIIB-class transcription factor binding,-
6926,0,107,2,77,305,15,0,1,15,0,68,0,TBX3;T-box 3,GO:0005634//nucleus,"GO:0030539//male genitalia development;GO:0001568//blood vessel development;GO:0008284//positive regulation of cell proliferation;GO:0048332//mesoderm morphogenesis;GO:0043066//negative regulation of apoptotic process;GO:0060021//palate development;GO:0009887//organ morphogenesis;GO:2000648//positive regulation of stem cell proliferation;GO:0006351//transcription, DNA-templated;GO:0030540//female genitalia development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010159//specification of organ position;GO:0060412//ventricular septum morphogenesis;GO:0045787//positive regulation of cell cycle;GO:0003151//outflow tract morphogenesis;GO:0060931//sinoatrial node cell development;GO:0019827//stem cell maintenance;GO:0035136//forelimb morphogenesis;GO:0001501//skeletal system development;GO:0035115//embryonic forelimb morphogenesis;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0032275//luteinizing hormone secretion;GO:0003167//atrioventricular bundle cell differentiation;GO:0090398//cellular senescence;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0045662//negative regulation of myoblast differentiation;GO:0021761//limbic system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042733//embryonic digit morphogenesis;GO:0001947//heart looping;GO:0060596//mammary placode formation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0060923//cardiac muscle cell fate commitment;GO:0046884//follicle-stimulating hormone secretion;GO:0008595//anterior/posterior axis specification, embryo;GO:0030879//mammary gland development;GO:0007569//cell aging;GO:0045892//negative regulation of transcription, DNA-templated",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding,-
6927,0,53,48,77,30,28,0,0,25,0,108,0,HNF1A;HNF1 homeobox A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0043234//protein complex;GO:0005730//nucleolus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0042593//glucose homeostasis;GO:0030073//insulin secretion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046323//glucose import;GO:0035565//regulation of pronephros size;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0035623//renal glucose absorption;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding,K08036//Maturity onset diabetes of the young
6928,0,0,0,1,0,0,0,0,24,0,2,0,HNF1B;HNF1 homeobox B,GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005730//nucleolus,"GO:0031018//endocrine pancreas development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0030902//hindbrain development;GO:0030073//insulin secretion;GO:0001826//inner cell mass cell differentiation;GO:0001714//endodermal cell fate specification;GO:0006366//transcription from RNA polymerase II promoter;GO:0060261//positive regulation of transcription initiation from RNA polymerase II promoter;GO:0048806//genitalia development;GO:0048793//pronephros development;GO:0009749//response to glucose;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030111//regulation of Wnt signaling pathway;GO:0072181//mesonephric duct formation;GO:0050673//epithelial cell proliferation;GO:0048557//embryonic digestive tract morphogenesis;GO:0001822//kidney development;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development;GO:0042663//regulation of endodermal cell fate specification;GO:0061017//hepatoblast differentiation;GO:0035565//regulation of pronephros size;GO:0039020//pronephric nephron tubule development;GO:0048754//branching morphogenesis of an epithelial tube;GO:0072095//regulation of branch elongation involved in ureteric bud branching;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0061296//negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis",GO:0044212//transcription regulatory region DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,K08034//Maturity onset diabetes of the young
6929,110,0,0,4,8,1,31,107,50,100,17,306,TCF3;transcription factor 3,GO:0000788//nuclear nucleosome;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0032496//response to lipopolysaccharide;GO:0033152//immunoglobulin V(D)J recombination;GO:0050821//protein stabilization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048541//Peyer's patch development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051149//positive regulation of muscle cell differentiation;GO:0042493//response to drug;GO:0030890//positive regulation of B cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0048468//cell development;GO:0002326//B cell lineage commitment;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0033077//T cell differentiation in thymus;GO:0045787//positive regulation of cell cycle;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001779//natural killer cell differentiation;GO:0030183//B cell differentiation;GO:0043967//histone H4 acetylation;GO:0042692//muscle cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0043966//histone H3 acetylation",GO:0070888//E-box binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0044212//transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0070644//vitamin D response element binding;GO:0003713//transcription coactivator activity;GO:0043425//bHLH transcription factor binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0070491//repressing transcription factor binding;GO:0035326//enhancer binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K09063//Transcriptional misregulation in cancer;HTLV-I infection
693121,0,0,0,0,0,0,0,0,8,0,0,0,MIR411;microRNA 411,-,-,-,-
693126,0,0,0,0,0,19,0,0,0,0,13,0,MIR548A2;microRNA 548a-2,-,-,-,-
693127,0,0,0,0,0,0,0,0,0,0,0,1,MIR548A3;microRNA 548a-3,-,-,-,-
693130,0,0,55,55,39,0,0,0,0,0,20,0,MIR548D1;microRNA 548d-1,-,-,-,-
693138,0,0,0,0,0,0,10,0,0,0,0,0,MIR553;microRNA 553,-,-,-,-
693141,0,0,0,2,0,0,0,0,0,0,0,0,MIR556;microRNA 556,-,-,-,-
693146,0,0,0,0,0,0,0,0,8,0,0,0,MIR561;microRNA 561,-,-,-,-
693148,0,0,0,0,0,0,0,0,0,0,11,0,MIR563;microRNA 563,-,-,-,-
693149,0,0,0,0,0,0,0,82,0,0,7,0,MIR564;microRNA 564,-,-,-,-
693151,0,0,0,0,0,0,2,0,0,0,0,0,MIR566;microRNA 566,-,-,-,K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
693155,0,0,0,0,0,0,0,0,3,0,0,0,MIR570;microRNA 570,-,-,-,-
693171,0,0,0,0,0,0,0,0,10,0,0,0,MIR586;microRNA 586,-,-,-,-
693176,0,0,0,0,0,12,0,0,13,0,0,0,MIR591;microRNA 591,-,-,-,-
693177,0,0,0,0,0,0,0,0,16,0,0,0,MIR592;microRNA 592,-,-,-,-
693178,0,0,0,0,0,0,0,0,21,0,0,0,MIR593;microRNA 593,-,-,-,-
693181,0,0,0,0,0,0,0,0,16,0,0,0,MIR596;microRNA 596,-,-,-,-
693186,0,0,0,0,0,0,0,0,0,0,0,4,MIR601;microRNA 601,-,-,-,-
693187,0,0,0,0,0,0,0,0,7,0,0,0,MIR602;microRNA 602,-,-,-,-
693189,0,0,0,0,0,0,0,0,0,9,0,0,MIR604;microRNA 604,-,-,-,-
693192,0,0,0,0,0,0,0,1,0,252,0,0,MIR607;microRNA 607,-,-,-,-
693198,0,0,0,0,0,0,0,0,7,0,0,0,MIR613;microRNA 613,-,-,-,-
6932,28,0,0,0,6,0,37,0,22,0,0,0,"TCF7;transcription factor 7 (T-cell specific, HMG-box)",GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0046632//alpha-beta T cell differentiation;GO:0042127//regulation of cell proliferation;GO:0071353//cellular response to interleukin-4;GO:0021915//neural tube development;GO:0048557//embryonic digestive tract morphogenesis;GO:0033153//T cell receptor V(D)J recombination;GO:0048699//generation of neurons;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006955//immune response;GO:0044336//canonical Wnt signaling pathway involved in negative regulation of apoptotic process;GO:0006351//transcription, DNA-templated;GO:0060070//canonical Wnt signaling pathway;GO:0048619//embryonic hindgut morphogenesis;GO:0030538//embryonic genitalia morphogenesis;GO:0007420//brain development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding;GO:0008013//beta-catenin binding;GO:0003682//chromatin binding,K02620//Colorectal cancer;Thyroid cancer;Melanogenesis;Adherens junction;Wnt signaling pathway;Endometrial cancer;Prostate cancer;Basal cell carcinoma;Acute myeloid leukemia;Pathways in cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
693202,0,0,0,0,0,0,0,0,6,0,0,0,MIR617;microRNA 617,-,-,-,-
693203,0,0,0,0,0,0,0,0,2,0,0,0,MIR618;microRNA 618,-,-,-,-
693215,0,0,0,0,0,0,0,0,0,0,5,0,MIR630;microRNA 630,-,-,-,-
693216,0,0,0,0,0,0,0,0,14,0,0,0,MIR631;microRNA 631,-,-,-,-
693219,0,0,0,0,0,0,0,0,26,0,0,0,MIR634;microRNA 634,-,-,-,-
693222,123,0,0,0,0,0,0,3,14,0,0,0,MIR637;microRNA 637,-,-,-,-
693229,0,0,0,0,0,0,36,0,0,0,0,0,MIR644A;microRNA 644a,-,-,-,-
693231,0,0,0,0,0,0,0,0,9,0,0,0,MIR646;microRNA 646,-,-,-,-
693234,0,0,0,0,0,0,0,0,0,5,0,0,MIR649;microRNA 649,-,-,-,-
693235,0,0,0,0,0,0,0,0,5,0,0,0,MIR92B;microRNA 92b,-,-,-,K04659//ECM-receptor interaction;Phagosome;Malaria;TGF-beta signaling pathway;Focal adhesion;Bladder cancer;p53 signaling pathway
6934,77,0,0,0,28,0,0,2,16,0,0,0,"TCF7L2;transcription factor 7-like 2 (T-cell specific, HMG-box)",GO:0032993//protein-DNA complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016605//PML body;GO:0070369//beta-catenin-TCF7L2 complex;GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0048713//regulation of oligodendrocyte differentiation;GO:0044334//canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition;GO:0030538//embryonic genitalia morphogenesis;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0030282//bone mineralization;GO:0046827//positive regulation of protein export from nucleus;GO:0032024//positive regulation of insulin secretion;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009791//post-embryonic development;GO:0009267//cellular response to starvation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035019//somatic stem cell maintenance;GO:0007050//cell cycle arrest;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0008283//cell proliferation;GO:0048641//regulation of skeletal muscle tissue development;GO:0043588//skin development;GO:0006351//transcription, DNA-templated;GO:0032092//positive regulation of protein binding;GO:0007420//brain development;GO:0050679//positive regulation of epithelial cell proliferation;GO:0035411//catenin import into nucleus;GO:0032350//regulation of hormone metabolic process;GO:0031641//regulation of myelination;GO:0010909//positive regulation of heparan sulfate proteoglycan biosynthetic process;GO:0051897//positive regulation of protein kinase B signaling;GO:0042593//glucose homeostasis;GO:0009749//response to glucose;GO:0001568//blood vessel development;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:1901142//insulin metabolic process;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0043570//maintenance of DNA repeat elements;GO:0046621//negative regulation of organ growth;GO:0043065//positive regulation of apoptotic process;GO:0005977//glycogen metabolic process;GO:0045722//positive regulation of gluconeogenesis;GO:0014003//oligodendrocyte development;GO:0045444//fat cell differentiation;GO:0021915//neural tube development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048625//myoblast fate commitment;GO:0006006//glucose metabolic process;GO:0030514//negative regulation of BMP signaling pathway;GO:0035264//multicellular organism growth;GO:0048619//embryonic hindgut morphogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0048660//regulation of smooth muscle cell proliferation;GO:0045599//negative regulation of fat cell differentiation;GO:0060325//face morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031016//pancreas development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0048557//embryonic digestive tract morphogenesis;GO:0032252//secretory granule localization;GO:0021983//pituitary gland development;GO:0048699//generation of neurons",GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0008013//beta-catenin binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0035257//nuclear hormone receptor binding;GO:0045295//gamma-catenin binding;GO:0070016//armadillo repeat domain binding;GO:0003682//chromatin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0044212//transcription regulatory region DNA binding,K04491//Endometrial cancer;Wnt signaling pathway;Adherens junction;Melanogenesis;Colorectal cancer;Thyroid cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Acute myeloid leukemia;Basal cell carcinoma;Prostate cancer
6935,0,0,0,0,0,22,38,1,37,0,6,0,ZEB1;zinc finger E-box binding homeobox 1,GO:0005730//nucleolus;GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0033081//regulation of T cell differentiation in thymus;GO:0031667//response to nutrient levels;GO:0045892//negative regulation of transcription, DNA-templated;GO:0010464//regulation of mesenchymal cell proliferation;GO:0048704//embryonic skeletal system morphogenesis;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051150//regulation of smooth muscle cell differentiation;GO:0030857//negative regulation of epithelial cell differentiation;GO:0090103//cochlea morphogenesis;GO:0045666//positive regulation of neuron differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0048596//embryonic camera-type eye morphogenesis;GO:0008283//cell proliferation;GO:0006955//immune response;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007389//pattern specification process;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030900//forebrain development;GO:0014823//response to activity;GO:0008285//negative regulation of cell proliferation;GO:0071230//cellular response to amino acid stimulus;GO:0048752//semicircular canal morphogenesis;GO:0051216//cartilage development",GO:0008270//zinc ion binding;GO:0070888//E-box binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity,K09299//Transcriptional misregulation in cancer
6936,0,49,1,53,89,32,0,33,54,10,56,0,GCFC2;GC-rich sequence DNA-binding factor 2,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0071008//U2-type post-mRNA release spliceosomal complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000245//spliceosomal complex assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
6938,0,0,0,12,37,0,29,0,28,0,0,0,TCF12;transcription factor 12,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0045666//positive regulation of neuron differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006955//immune response",GO:0046332//SMAD binding;GO:0043425//bHLH transcription factor binding;GO:0035326//enhancer binding;GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0070888//E-box binding,-
6939,0,0,0,0,0,0,15,0,0,0,0,0,TCF15;transcription factor 15 (basic helix-loop-helix),GO:0005634//nucleus,"GO:0048705//skeletal system morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045198//establishment of epithelial cell apical/basal polarity;GO:0042755//eating behavior;GO:0003016//respiratory system process;GO:0050884//neuromuscular process controlling posture;GO:0036342//post-anal tail morphogenesis;GO:0001756//somitogenesis;GO:0048644//muscle organ morphogenesis;GO:0016265//death;GO:0048339//paraxial mesoderm development;GO:0007498//mesoderm development;GO:0060231//mesenchymal to epithelial transition;GO:0006351//transcription, DNA-templated;GO:0043588//skin development;GO:0043583//ear development",GO:0046983//protein dimerization activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
694,0,0,0,10,66,26,23,0,18,0,3,0,"BTG1;B-cell translocation gene 1, anti-proliferative",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0045603//positive regulation of endothelial cell differentiation;GO:0045663//positive regulation of myoblast differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045766//positive regulation of angiogenesis;GO:0016477//cell migration",GO:0003712//transcription cofactor activity;GO:0019899//enzyme binding;GO:0019900//kinase binding;GO:0005515//protein binding,K14443//RNA degradation
6940,0,0,0,3,39,0,0,0,0,0,0,0,ZNF354A;zinc finger protein 354A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007605//sensory perception of sound;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
6941,0,0,1,0,0,0,0,1,0,0,0,0,TCF19;transcription factor 19,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008283//cell proliferation",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
6942,0,0,0,13,58,22,55,1,35,0,0,0,TCF20;transcription factor 20 (AR1),GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,K09188//Lysine degradation
6943,77,0,0,0,0,0,0,0,12,0,0,0,TCF21;transcription factor 21,GO:0005634//nucleus,"GO:0030855//epithelial cell differentiation;GO:0001944//vasculature development;GO:0014707//branchiomeric skeletal muscle development;GO:0001763//morphogenesis of a branching structure;GO:0060008//Sertoli cell differentiation;GO:0001657//ureteric bud development;GO:0007530//sex determination;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0060426//lung vasculature development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072277//metanephric glomerular capillary formation;GO:0060539//diaphragm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048608//reproductive structure development;GO:0072162//metanephric mesenchymal cell differentiation;GO:0060021//palate development;GO:0006351//transcription, DNA-templated;GO:0048732//gland development;GO:0048536//spleen development;GO:0048557//embryonic digestive tract morphogenesis;GO:0001822//kidney development;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0060425//lung morphogenesis;GO:0048286//lung alveolus development;GO:0060435//bronchiole development;GO:0060541//respiratory system development;GO:0032835//glomerulus development",GO:0070888//E-box binding;GO:0042826//histone deacetylase binding;GO:0050681//androgen receptor binding;GO:0046983//protein dimerization activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0043425//bHLH transcription factor binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
6944,0,0,0,0,22,0,0,0,1,0,0,1,VPS72;vacuolar protein sorting 72 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0043234//protein complex;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0016568//chromatin modification;GO:0035019//somatic stem cell maintenance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization",GO:0003677//DNA binding;GO:0005515//protein binding,-
6945,0,3,39,21,67,0,0,165,31,76,70,328,"MLX;MLX, MAX dimerization protein",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006913//nucleocytoplasmic transport;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006112//energy reserve metabolic process;GO:0006351//transcription, DNA-templated;GO:0031325//positive regulation of cellular metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
6947,0,0,0,0,0,0,12,0,0,0,0,0,"TCN1;transcobalamin I (vitamin B12 binding protein, R binder family)",GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0015889//cobalamin transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0009235//cobalamin metabolic process;GO:0006824//cobalt ion transport;GO:0006766//vitamin metabolic process,GO:0031419//cobalamin binding,K14615//Vitamin digestion and absorption
6948,54,0,49,0,0,15,0,1,30,0,6,0,TCN2;transcobalamin II,GO:0043202//lysosomal lumen;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0005576//extracellular region,GO:0015889//cobalamin transport;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0009235//cobalamin metabolic process;GO:0006824//cobalt ion transport;GO:0006766//vitamin metabolic process,GO:0046872//metal ion binding;GO:0031419//cobalamin binding,K14619//Vitamin digestion and absorption
6949,0,16,0,0,13,1,56,43,99,0,3,0,TCOF1;Treacher Collins-Franceschetti syndrome 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0001501//skeletal system development;GO:0006810//transport,GO:0005215//transporter activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14562//Ribosome biogenesis in eukaryotes
695,0,0,0,0,0,25,0,78,37,0,0,0,BTK;Bruton agammaglobulinemia tyrosine kinase,GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0042629//mast cell granule;GO:0043231//intracellular membrane-bounded organelle,"GO:0006351//transcription, DNA-templated;GO:0002224//toll-like receptor signaling pathway;GO:0002250//adaptive immune response;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0007498//mesoderm development;GO:0035556//intracellular signal transduction;GO:0010033//response to organic substance;GO:0048469//cell maturation;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0050853//B cell receptor signaling pathway;GO:0000302//response to reactive oxygen species;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0002553//histamine secretion by mast cell;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006468//protein phosphorylation;GO:0097190//apoptotic signaling pathway;GO:0002721//regulation of B cell cytokine production;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0019722//calcium-mediated signaling;GO:0045579//positive regulation of B cell differentiation;GO:0002902//regulation of B cell apoptotic process;GO:0042113//B cell activation;GO:0046777//protein autophosphorylation","GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0005524//ATP binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity",K07370//Osteoclast differentiation;Primary immunodeficiency;Fc epsilon RI signaling pathway;NF-kappa B signaling pathway;B cell receptor signaling pathway
6950,0,1240,957,2371,2921,9,19,75,51,499,956,360,TCP1;t-complex 1,GO:0005832//chaperonin-containing T-complex;GO:0005720//nuclear heterochromatin;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0044297//cell body;GO:0005813//centrosome;GO:0001669//acrosomal vesicle;GO:0005829//cytosol;GO:0002199//zona pellucida receptor complex;GO:0000242//pericentriolar material;GO:0005874//microtubule,GO:0007021//tubulin complex assembly;GO:0044267//cellular protein metabolic process;GO:0007339//binding of sperm to zona pellucida;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding,GO:0051082//unfolded protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0005524//ATP binding,-
6953,35,0,0,1,0,0,0,0,17,0,0,0,TCP10;t-complex 10,GO:0005829//cytosol,-,-,-
6954,95,2,0,9,27,0,0,0,17,0,8,0,"TCP11;t-complex 11, testis-specific",GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,-,-
696,0,0,0,0,0,0,0,81,34,0,0,0,"BTN1A1;butyrophilin, subfamily 1, member A1",GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,-,GO:0004872//receptor activity,-
6975,0,0,0,0,0,5,0,0,62,0,0,0,TECTB;tectorin beta,GO:0031225//anchored component of membrane;GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane,-,-,K13912//Salivary secretion
6988,0,12,0,20,1,0,0,0,29,0,20,0,TCTA;T-cell leukemia translocation altered,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
699,0,0,1,0,0,0,87,0,27,0,0,0,BUB1;BUB1 mitotic checkpoint serine/threonine kinase,"GO:0005730//nucleolus;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0005737//cytoplasm",GO:0007094//mitotic spindle assembly checkpoint;GO:0008283//cell proliferation;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation;GO:0007093//mitotic cell cycle checkpoint;GO:0016032//viral process;GO:0051983//regulation of chromosome segregation;GO:0071173//spindle assembly checkpoint;GO:0007063//regulation of sister chromatid cohesion;GO:0007067//mitotic nuclear division,GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K02178//Oocyte meiosis;Meiosis - yeast;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Cell cycle
6990,0,59,0,67,99,0,0,0,29,0,0,0,"DYNLT3;dynein, light chain, Tctex-type 3",GO:0000777//condensed chromosome kinetochore;GO:0005868//cytoplasmic dynein complex;GO:0000776//kinetochore;GO:0005874//microtubule;GO:0005634//nucleus,GO:0007067//mitotic nuclear division;GO:0008152//metabolic process;GO:0007346//regulation of mitotic cell cycle;GO:0006810//transport,GO:0003774//motor activity;GO:0042802//identical protein binding,-
6991,0,0,0,0,0,10,0,102,5,0,0,0,TCTE3;t-complex-associated-testis-expressed 3,GO:0016020//membrane;GO:0005874//microtubule;GO:0030286//dynein complex;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0006810//transport,GO:0003774//motor activity,-
6992,0,0,0,0,13,0,0,0,16,0,0,0,"PPP1R11;protein phosphatase 1, regulatory (inhibitor) subunit 11",GO:0005737//cytoplasm,GO:0043086//negative regulation of catalytic activity,GO:0005515//protein binding;GO:0004864//protein phosphatase inhibitor activity,-
6993,0,35,1,12,8,0,17,0,0,0,0,0,"DYNLT1;dynein, light chain, Tctex-type 1",GO:0005874//microtubule;GO:0005819//spindle;GO:0005868//cytoplasmic dynein complex;GO:0005794//Golgi apparatus,GO:0008152//metabolic process;GO:0019060//intracellular transport of viral protein in host cell;GO:0046718//viral entry into host cell;GO:0075521//microtubule-dependent intracellular transport of viral material towards nucleus;GO:0050768//negative regulation of neurogenesis;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0000132//establishment of mitotic spindle orientation;GO:0032314//regulation of Rac GTPase activity;GO:0048812//neuron projection morphogenesis;GO:0007067//mitotic nuclear division;GO:0051493//regulation of cytoskeleton organization,GO:0003774//motor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,-
6996,0,10,0,12,33,4,13,0,20,0,0,0,TDG;thymine-DNA glycosylase,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016605//PML body;GO:0005886//plasma membrane,"GO:0035562//negative regulation of chromatin binding;GO:0006281//DNA repair;GO:0080111//DNA demethylation;GO:0016568//chromatin modification;GO:0009790//embryo development;GO:0006284//base-excision repair;GO:0006298//mismatch repair;GO:0045008//depyrimidination;GO:0040029//regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032091//negative regulation of protein binding;GO:0006366//transcription from RNA polymerase II promoter",GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0019104//DNA N-glycosylase activity;GO:0003684//damaged DNA binding;GO:0043566//structure-specific DNA binding;GO:0003690//double-stranded DNA binding;GO:0032183//SUMO binding;GO:0005080//protein kinase C binding;GO:0030983//mismatched DNA binding;GO:0008263//pyrimidine-specific mismatch base pair DNA N-glycosylase activity,K03649//Base excision repair
6997,104,0,0,0,0,0,0,36,67,0,5,0,TDGF1;teratocarcinoma-derived growth factor 1,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0019897//extrinsic component of plasma membrane;GO:0005615//extracellular space;GO:0031225//anchored component of membrane;GO:0016324//apical plasma membrane;GO:0045121//membrane raft;GO:0009986//cell surface;GO:0005794//Golgi apparatus,"GO:0055007//cardiac muscle cell differentiation;GO:0071354//cellular response to interleukin-6;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0030879//mammary gland development;GO:0030154//cell differentiation;GO:0008595//anterior/posterior axis specification, embryo;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0018105//peptidyl-serine phosphorylation;GO:0071346//cellular response to interferon-gamma;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0060070//canonical Wnt signaling pathway;GO:0030335//positive regulation of cell migration;GO:0001701//in utero embryonic development;GO:0001570//vasculogenesis;GO:0009966//regulation of signal transduction;GO:0001763//morphogenesis of a branching structure;GO:0007369//gastrulation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0071356//cellular response to tumor necrosis factor;GO:0010595//positive regulation of endothelial cell migration;GO:0001954//positive regulation of cell-matrix adhesion;GO:0048146//positive regulation of fibroblast proliferation;GO:0043066//negative regulation of apoptotic process;GO:0030509//BMP signaling pathway;GO:0009790//embryo development;GO:0008284//positive regulation of cell proliferation;GO:0007507//heart development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation",GO:0005102//receptor binding;GO:0008083//growth factor activity;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
6998,0,0,0,0,0,0,31,27,12,0,0,0,TDGF1P3;teratocarcinoma-derived growth factor 1 pseudogene 3,GO:0009279//cell outer membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction,GO:0008083//growth factor activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
6999,0,0,0,0,0,0,6,58,23,0,0,0,"TDO2;tryptophan 2,3-dioxygenase",GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0019441//tryptophan catabolic process to kynurenine;GO:0006569//tryptophan catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0055114//oxidation-reduction process;GO:0019442//tryptophan catabolic process to acetyl-CoA,"GO:0020037//heme binding;GO:0019825//oxygen binding;GO:0016597//amino acid binding;GO:0004833//tryptophan 2,3-dioxygenase activity;GO:0046872//metal ion binding",K00453//Metabolic pathways;Tryptophan metabolism
70,0,0,0,0,0,0,0,0,29,161,0,0,"ACTC1;actin, alpha, cardiac muscle 1","GO:0016020//membrane;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0042643//actomyosin, actin portion;GO:0005884//actin filament;GO:0031674//I band;GO:0030017//sarcomere",GO:0060048//cardiac muscle contraction;GO:0030048//actin filament-based movement;GO:0042493//response to drug;GO:0030049//muscle filament sliding;GO:0006200//ATP catabolic process;GO:0030240//skeletal muscle thin filament assembly;GO:0031032//actomyosin structure organization;GO:0055003//cardiac myofibril assembly;GO:0006915//apoptotic process;GO:0055008//cardiac muscle tissue morphogenesis;GO:0033275//actin-myosin filament sliding;GO:0043066//negative regulation of apoptotic process;GO:0045471//response to ethanol;GO:0060047//heart contraction,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0017022//myosin binding,K12314//Cardiac muscle contraction;Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
7001,0,50,0,10,68,17,1,0,2,0,0,0,PRDX2;peroxiredoxin 2,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0043066//negative regulation of apoptotic process;GO:0006979//response to oxidative stress;GO:0055114//oxidation-reduction process;GO:0019430//removal of superoxide radicals;GO:0042744//hydrogen peroxide catabolic process;GO:0042981//regulation of apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0034599//cellular response to oxidative stress,GO:0016209//antioxidant activity;GO:0008379//thioredoxin peroxidase activity,K03386//Amoebiasis
7003,0,0,0,46,115,23,0,113,37,0,26,0,TEAD1;TEA domain family member 1 (SV40 transcriptional enhancer factor),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0035329//hippo signaling;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7004,0,0,0,11,0,46,0,0,17,0,22,0,TEAD4;TEA domain family member 4,GO:0005654//nucleoplasm,GO:0001501//skeletal system development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0010467//gene expression;GO:0035329//hippo signaling;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7005,0,0,0,11,1,0,0,1,13,0,0,0,TEAD3;TEA domain family member 3,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007565//female pregnancy;GO:0035329//hippo signaling;GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding,-
7006,78,0,0,0,0,1,0,0,25,0,0,0,TEC;tec protein tyrosine kinase,GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0010543//regulation of platelet activation;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0045087//innate immune response;GO:0042246//tissue regeneration;GO:0007229//integrin-mediated signaling pathway;GO:0050853//B cell receptor signaling pathway,GO:0008289//lipid binding;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K07364//Osteoclast differentiation;T cell receptor signaling pathway
7007,8,1,0,0,0,31,27,4,17,209,35,0,TECTA;tectorin alpha,GO:0005578//proteinaceous extracellular matrix;GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007160//cell-matrix adhesion;GO:0007605//sensory perception of sound,-,K03900//Complement and coagulation cascades;Focal adhesion;ECM-receptor interaction
7008,34,0,0,0,1,12,77,54,44,0,12,0,TEF;thyrotrophic embryonic factor,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048511//rhythmic process",GO:0003690//double-stranded DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity,-
7009,0,0,0,7,62,12,34,49,16,0,17,0,TMBIM6;transmembrane BAX inhibitor motif containing 6,GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0006986//response to unfolded protein;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process,-,-
701,0,0,0,0,0,0,5,0,13,0,5,0,BUB1B;BUB1 mitotic checkpoint serine/threonine kinase B,GO:0005815//microtubule organizing center;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex;GO:0000940//condensed chromosome outer kinetochore;GO:0000778//condensed nuclear chromosome kinetochore;GO:0005737//cytoplasm;GO:0051233//spindle midzone;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore,"GO:0006915//apoptotic process;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0007094//mitotic spindle assembly checkpoint;GO:0008283//cell proliferation;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0034501//protein localization to kinetochore;GO:0071459//protein localization to chromosome, centromeric region;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007093//mitotic cell cycle checkpoint;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division",GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K06637//HTLV-I infection;Cell cycle
7010,0,0,0,0,0,6,15,0,113,182,0,0,"TEK;TEK tyrosine kinase, endothelial",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005902//microvillus;GO:0005911//cell-cell junction;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane;GO:0001725//stress fiber;GO:0005884//actin filament;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane,GO:0051897//positive regulation of protein kinase B signaling;GO:0051259//protein oligomerization;GO:0001935//endothelial cell proliferation;GO:0002040//sprouting angiogenesis;GO:0001525//angiogenesis;GO:0007507//heart development;GO:0043114//regulation of vascular permeability;GO:2000251//positive regulation of actin cytoskeleton reorganization;GO:0010595//positive regulation of endothelial cell migration;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0016525//negative regulation of angiogenesis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0007596//blood coagulation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0031100//organ regeneration;GO:0007267//cell-cell signaling;GO:0045766//positive regulation of angiogenesis;GO:0048014//Tie signaling pathway;GO:0051894//positive regulation of focal adhesion assembly;GO:0060347//heart trabecula formation;GO:0001938//positive regulation of endothelial cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0001958//endochondral ossification;GO:0051591//response to cAMP;GO:0060216//definitive hemopoiesis;GO:0046777//protein autophosphorylation;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0032878//regulation of establishment or maintenance of cell polarity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0001666//response to hypoxia;GO:0007160//cell-matrix adhesion;GO:0043434//response to peptide hormone;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0050728//negative regulation of inflammatory response;GO:1902533//positive regulation of intracellular signal transduction;GO:0043627//response to estrogen;GO:0033138//positive regulation of peptidyl-serine phosphorylation,GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004872//receptor activity;GO:0019838//growth factor binding;GO:0005524//ATP binding,K05121//Rheumatoid arthritis
7011,82,36,23,22,57,35,54,3,96,145,23,320,TEP1;telomerase-associated protein 1,"GO:0016363//nuclear matrix;GO:0000781//chromosome, telomeric region;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0005697//telomerase holoenzyme complex",GO:0000722//telomere maintenance via recombination;GO:0006278//RNA-dependent DNA replication,GO:0005524//ATP binding;GO:0003723//RNA binding;GO:0003720//telomerase activity,-
7013,0,0,0,1,14,15,0,0,51,0,0,0,TERF1;telomeric repeat binding factor (NIMA-interacting) 1,"GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000783//nuclear telomere cap complex;GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region",GO:0051974//negative regulation of telomerase activity;GO:0000723//telomere maintenance;GO:0001309//age-dependent telomere shortening;GO:0007004//telomere maintenance via telomerase;GO:0008156//negative regulation of DNA replication;GO:0051260//protein homooligomerization;GO:0031116//positive regulation of microtubule polymerization;GO:0045931//positive regulation of mitotic cell cycle;GO:0042493//response to drug;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0032214//negative regulation of telomere maintenance via semi-conservative replication;GO:0045840//positive regulation of mitosis;GO:0007094//mitotic spindle assembly checkpoint;GO:0007067//mitotic nuclear division;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0010834//telomere maintenance via telomere shortening,"GO:0003691//double-stranded telomeric DNA binding;GO:0008301//DNA binding, bending;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0008017//microtubule binding;GO:0042162//telomeric DNA binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding",-
7014,18,1,0,4,102,0,17,0,60,0,5,0,TERF2;telomeric repeat binding factor 2,"GO:0000783//nuclear telomere cap complex;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus;GO:0030870//Mre11 complex;GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0005730//nucleolus","GO:0032206//positive regulation of telomere maintenance;GO:0031848//protection from non-homologous end joining at telomere;GO:0000723//telomere maintenance;GO:0032214//negative regulation of telomere maintenance via semi-conservative replication;GO:0016233//telomere capping;GO:0001309//age-dependent telomere shortening;GO:0032205//negative regulation of telomere maintenance;GO:0007049//cell cycle;GO:0007004//telomere maintenance via telomerase;GO:0031627//telomeric loop formation;GO:0090398//cellular senescence;GO:0070198//protein localization to chromosome, telomeric region;GO:0001701//in utero embryonic development;GO:0010834//telomere maintenance via telomere shortening",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008022//protein C-terminus binding;GO:0003682//chromatin binding;GO:0003691//double-stranded telomeric DNA binding;GO:0042162//telomeric DNA binding,-
7015,0,0,0,0,0,0,0,96,56,122,0,0,TERT;telomerase reverse transcriptase,"GO:0005737//cytoplasm;GO:0000781//chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex;GO:0005697//telomerase holoenzyme complex;GO:0016605//PML body;GO:0005730//nucleolus",GO:0000723//telomere maintenance;GO:0090399//replicative senescence;GO:0032203//telomere formation via telomerase;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0022616//DNA strand elongation;GO:0007004//telomere maintenance via telomerase,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0070034//telomeric RNA binding;GO:0003721//telomeric template RNA reverse transcriptase activity;GO:0003720//telomerase activity;GO:0042162//telomeric DNA binding,K11126//HTLV-I infection
7016,0,0,0,5,0,15,0,0,26,0,0,0,TESK1;testis-specific kinase 1,GO:0005829//cytosol,GO:0034329//cell junction assembly;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007283//spermatogenesis,GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity,-
7018,33,0,0,0,0,38,0,106,36,0,0,0,TF;transferrin,GO:0016324//apical plasma membrane;GO:0045178//basal part of cell;GO:0031982//vesicle;GO:0005769//early endosome;GO:0005770//late endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0034774//secretory granule lumen;GO:0055037//recycling endosome;GO:0030139//endocytic vesicle;GO:0005905//coated pit;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0009925//basal plasma membrane;GO:0005615//extracellular space,GO:0007596//blood coagulation;GO:0001895//retina homeostasis;GO:0033572//transferrin transport;GO:0030168//platelet activation;GO:0055085//transmembrane transport;GO:0006879//cellular iron ion homeostasis;GO:0002576//platelet degranulation,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0008199//ferric iron binding,K14736//Mineral absorption
7019,0,1,0,48,110,15,0,0,0,0,9,0,"TFAM;transcription factor A, mitochondrial",GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005759//mitochondrial matrix;GO:0005634//nucleus,"GO:0006390//transcription from mitochondrial promoter;GO:0033108//mitochondrial respiratory chain complex assembly;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006391//transcription initiation from mitochondrial promoter;GO:0006356//regulation of transcription from RNA polymerase I promoter;GO:0010467//gene expression;GO:0006261//DNA-dependent DNA replication","GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0070363//mitochondrial light strand promoter sense binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0031072//heat shock protein binding;GO:0008301//DNA binding, bending;GO:0003682//chromatin binding",K11830//Huntington's disease
7020,0,0,0,6,35,0,0,0,2,0,23,0,TFAP2A;transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha),GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,"GO:0043525//positive regulation of neuron apoptotic process;GO:0061303//cornea development in camera-type eye;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:0060021//palate development;GO:0003404//optic vesicle morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0061029//eyelid development in camera-type eye;GO:0042472//inner ear morphogenesis;GO:0021884//forebrain neuron development;GO:0045664//regulation of neuron differentiation;GO:0001822//kidney development;GO:0035115//embryonic forelimb morphogenesis;GO:0072210//metanephric nephron development;GO:0060349//bone morphogenesis;GO:0021559//trigeminal nerve development;GO:0045595//regulation of cell differentiation;GO:0048730//epidermis morphogenesis;GO:0010172//embryonic body morphogenesis;GO:0043524//negative regulation of neuron apoptotic process;GO:0021506//anterior neuropore closure;GO:0003334//keratinocyte development;GO:0003151//outflow tract morphogenesis;GO:0003409//optic cup structural organization;GO:0030501//positive regulation of bone mineralization;GO:0070172//positive regulation of tooth mineralization;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0009880//embryonic pattern specification;GO:0060325//face morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030335//positive regulation of cell migration;GO:0071281//cellular response to iron ion;GO:0007605//sensory perception of sound;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048485//sympathetic nervous system development;GO:0060235//lens induction in camera-type eye;GO:0021623//oculomotor nerve formation;GO:0010842//retina layer formation;GO:0006366//transcription from RNA polymerase II promoter;GO:0014032//neural crest cell development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0071711//basement membrane organization;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000378//negative regulation of reactive oxygen species metabolic process",GO:0003682//chromatin binding;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0042803//protein homodimerization activity,-
7021,0,0,0,0,0,17,22,1,19,0,0,244,TFAP2B;transcription factor AP-2 beta (activating enhancer binding protein 2 beta),GO:0005634//nucleus,"GO:0097070//ductus arteriosus closure;GO:0006006//glucose metabolic process;GO:0010960//magnesium ion homeostasis;GO:0055074//calcium ion homeostasis;GO:0097276//cellular creatinine homeostasis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0003091//renal water homeostasis;GO:0097275//cellular ammonia homeostasis;GO:0006366//transcription from RNA polymerase II promoter;GO:0072017//distal tubule development;GO:0010842//retina layer formation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0035810//positive regulation of urine volume;GO:0042493//response to drug;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048485//sympathetic nervous system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0055075//potassium ion homeostasis;GO:0050796//regulation of insulin secretion;GO:0043524//negative regulation of neuron apoptotic process;GO:0035909//aorta morphogenesis;GO:0055078//sodium ion homeostasis;GO:0055062//phosphate ion homeostasis;GO:0097277//cellular urea homeostasis;GO:0045595//regulation of cell differentiation;GO:0072210//metanephric nephron development;GO:0035137//hindlimb morphogenesis;GO:0072044//collecting duct development;GO:0035136//forelimb morphogenesis;GO:0001822//kidney development;GO:0030510//regulation of BMP signaling pathway;GO:0042593//glucose homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0010226//response to lithium ion;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0043525//positive regulation of neuron apoptotic process;GO:0043588//skin development",GO:0001158//enhancer sequence-specific DNA binding;GO:0003677//DNA binding;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0043565//sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0000983//RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
7022,0,1,1,0,28,12,0,0,8,0,0,0,TFAP2C;transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma),GO:0005634//nucleus,"GO:0060598//dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis;GO:0021987//cerebral cortex development;GO:0006366//transcription from RNA polymerase II promoter;GO:0030718//germ-line stem cell maintenance;GO:0048733//sebaceous gland development;GO:0008584//male gonad development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045682//regulation of epidermis development;GO:0003334//keratinocyte development;GO:0035019//somatic stem cell maintenance;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001829//trophectodermal cell differentiation;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:0021877//forebrain neuron fate commitment;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0040029//regulation of gene expression, epigenetic;GO:0007267//cell-cell signaling;GO:0001942//hair follicle development",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003677//DNA binding;GO:0001047//core promoter binding;GO:0046983//protein dimerization activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
7023,0,1,0,0,14,31,0,0,24,0,9,0,TFAP4;transcription factor AP-4 (activating enhancer binding protein 4),GO:0017053//transcriptional repressor complex;GO:0005634//nucleus,"GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006366//transcription from RNA polymerase II promoter;GO:0071549//cellular response to dexamethasone stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043923//positive regulation by host of viral transcription;GO:0071157//negative regulation of cell cycle arrest;GO:0043065//positive regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0006461//protein complex assembly;GO:2001269//positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0043922//negative regulation by host of viral transcription;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043392//negative regulation of DNA binding",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0070888//E-box binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0003677//DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity,-
7024,90,30,1,21,143,18,14,0,41,0,0,0,TFCP2;transcription factor CP2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7025,0,0,0,0,0,13,6,0,23,0,0,0,"NR2F1;nuclear receptor subfamily 2, group F, member 1",GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0010977//negative regulation of neuron projection development;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0001764//neuron migration;GO:0021796//cerebral cortex regionalization;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter,GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding;GO:0044323//retinoic acid-responsive element binding,-
7026,0,0,0,6,6,14,8,0,25,113,11,0,"NR2F2;nuclear receptor subfamily 2, group F, member 2",GO:0005634//nucleus,"GO:0006629//lipid metabolic process;GO:0060707//trophoblast giant cell differentiation;GO:0060173//limb development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0060849//regulation of transcription involved in lymphatic endothelial cell fate commitment;GO:0030900//forebrain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001893//maternal placenta development;GO:0030522//intracellular receptor signaling pathway;GO:0009956//radial pattern formation;GO:0009952//anterior/posterior pattern specification;GO:0048514//blood vessel morphogenesis;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032355//response to estradiol;GO:0007519//skeletal muscle tissue development;GO:0001764//neuron migration;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0043401//steroid hormone mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060674//placenta blood vessel development;GO:0009566//fertilization;GO:0010596//negative regulation of endothelial cell migration",GO:0043565//sequence-specific DNA binding;GO:0001972//retinoic acid binding;GO:0003714//transcription corepressor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity,-
7027,0,0,1,0,27,0,0,0,10,0,0,0,TFDP1;transcription factor Dp-1,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex,"GO:0008283//cell proliferation;GO:0008544//epidermis development;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0097193//intrinsic apoptotic signaling pathway;GO:0010467//gene expression;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2000278//regulation of DNA biosynthetic process;GO:0006915//apoptotic process;GO:0000278//mitotic cell cycle;GO:0043276//anoikis;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003713//transcription coactivator activity;GO:0019904//protein domain specific binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K04683//TGF-beta signaling pathway;Cell cycle
7029,95,0,0,42,155,13,31,35,17,0,10,0,TFDP2;transcription factor Dp-2 (E2F dimerization partner 2),GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,"GO:0000278//mitotic cell cycle;GO:0010467//gene expression;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0007507//heart development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003712//transcription cofactor activity;GO:0019904//protein domain specific binding;GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K09392//Cell cycle
7030,0,0,1,11,28,12,38,33,32,35,11,0,TFE3;transcription factor binding to IGHM enhancer 3,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045785//positive regulation of cell adhesion;GO:0045670//regulation of osteoclast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006959//humoral immune response;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046983//protein dimerization activity;GO:0044212//transcription regulatory region DNA binding,K09105//Transcriptional misregulation in cancer
7032,0,0,0,0,0,20,0,0,20,0,13,0,TFF2;trefoil factor 2,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0019722//calcium-mediated signaling;GO:0008284//positive regulation of cell proliferation;GO:0007586//digestion;GO:0030334//regulation of cell migration;GO:0060455//negative regulation of gastric acid secretion;GO:0043031//negative regulation of macrophage activation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0070098//chemokine-mediated signaling pathway;GO:0050728//negative regulation of inflammatory response,GO:0031723//CXCR4 chemokine receptor binding;GO:0005515//protein binding,K01176//Pancreatic secretion;Starch and sucrose metabolism;Carbohydrate digestion and absorption;Salivary secretion;Porphyrin and chlorophyll metabolism;Metabolic pathways
7033,0,12,0,0,0,0,0,0,15,107,0,0,TFF3;trefoil factor 3 (intestinal),GO:0070062//extracellular vesicular exosome;GO:0032579//apical lamina of hyaline layer;GO:0005576//extracellular region;GO:0030141//secretory granule,GO:0007586//digestion;GO:0006952//defense response;GO:0043434//response to peptide hormone,-,-
7035,0,0,0,0,0,0,1,0,30,0,0,0,TFPI;tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor),GO:0031090//organelle membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0031225//anchored component of membrane,"GO:0010951//negative regulation of endopeptidase activity;GO:0007598//blood coagulation, extrinsic pathway;GO:0007596//blood coagulation",GO:0004866//endopeptidase inhibitor activity;GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades
7036,0,0,57,0,0,0,0,46,17,0,0,404,TFR2;transferrin receptor 2,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane,GO:0006826//iron ion transport;GO:0006879//cellular iron ion homeostasis;GO:0006898//receptor-mediated endocytosis,GO:0004998//transferrin receptor activity,K06503//Endocytosis;Hematopoietic cell lineage;Phagosome
7037,58,0,0,10,0,0,22,52,24,0,2,0,TFRC;transferrin receptor,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0031982//vesicle;GO:0055037//recycling endosome;GO:0048471//perinuclear region of cytoplasm;GO:0009986//cell surface;GO:0016020//membrane;GO:0005768//endosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005905//coated pit;GO:0005615//extracellular space;GO:0043231//intracellular membrane-bounded organelle;GO:0005887//integral component of plasma membrane,GO:0042127//regulation of cell proliferation;GO:0016032//viral process;GO:0097286//iron ion import;GO:0001558//regulation of cell growth;GO:0033572//transferrin transport;GO:0006879//cellular iron ion homeostasis;GO:0030316//osteoclast differentiation;GO:0006898//receptor-mediated endocytosis;GO:0045780//positive regulation of bone resorption;GO:0055085//transmembrane transport,GO:0003725//double-stranded RNA binding;GO:0042802//identical protein binding;GO:0004998//transferrin receptor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K06503//Hematopoietic cell lineage;Endocytosis;Phagosome
7038,31,0,26,0,0,0,55,0,185,0,18,1,TG;thyroglobulin,GO:0005887//integral component of plasma membrane;GO:0045202//synapse;GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0009986//cell surface,GO:0042446//hormone biosynthetic process;GO:0031641//regulation of myelination;GO:0006590//thyroid hormone generation;GO:0007165//signal transduction;GO:0007416//synapse assembly;GO:0030878//thyroid gland development;GO:0015705//iodide transport,GO:0005179//hormone activity;GO:0042043//neurexin family protein binding;GO:0004872//receptor activity,K10809//Autoimmune thyroid disease
7039,0,0,0,0,0,1,14,0,0,0,0,0,"TGFA;transforming growth factor, alpha",GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle,GO:0008283//cell proliferation;GO:0045840//positive regulation of mitosis;GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0060749//mammary gland alveolus development;GO:0042060//wound healing;GO:0050679//positive regulation of epithelial cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0051781//positive regulation of cell division;GO:0042493//response to drug;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001525//angiogenesis,GO:0008083//growth factor activity;GO:0004708//MAP kinase kinase activity;GO:0005515//protein binding;GO:0005154//epidermal growth factor receptor binding;GO:0001948//glycoprotein binding,K08774//Pathways in cancer;Non-small cell lung cancer;Pancreatic cancer;Prostate cancer;Glioma;ErbB signaling pathway;Renal cell carcinoma
7040,107,0,0,0,0,19,0,0,28,0,0,0,"TGFB1;transforming growth factor, beta 1",GO:0005634//nucleus;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0030424//axon;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005902//microvillus;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0072562//blood microparticle;GO:0005576//extracellular region,"GO:0042130//negative regulation of T cell proliferation;GO:0030214//hyaluronan catabolic process;GO:0032355//response to estradiol;GO:0048839//inner ear development;GO:0007050//cell cycle arrest;GO:0051098//regulation of binding;GO:0009611//response to wounding;GO:0030334//regulation of cell migration;GO:0022408//negative regulation of cell-cell adhesion;GO:0035066//positive regulation of histone acetylation;GO:0051101//regulation of DNA binding;GO:0032967//positive regulation of collagen biosynthetic process;GO:0070306//lens fiber cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0010628//positive regulation of gene expression;GO:0085029//extracellular matrix assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0034616//response to laminar fluid shear stress;GO:0043932//ossification involved in bone remodeling;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0070723//response to cholesterol;GO:0000060//protein import into nucleus, translocation;GO:0001657//ureteric bud development;GO:0060364//frontal suture morphogenesis;GO:0032570//response to progesterone;GO:0007492//endoderm development;GO:0045662//negative regulation of myoblast differentiation;GO:0002513//tolerance induction to self antigen;GO:0019058//viral life cycle;GO:0031334//positive regulation of protein complex assembly;GO:0007406//negative regulation of neuroblast proliferation;GO:0010742//macrophage derived foam cell differentiation;GO:0007596//blood coagulation;GO:0048535//lymph node development;GO:0001934//positive regulation of protein phosphorylation;GO:0019049//evasion or tolerance of host defenses by virus;GO:0002576//platelet degranulation;GO:0007568//aging;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0002248//connective tissue replacement involved in inflammatory response wound healing;GO:0030501//positive regulation of bone mineralization;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0019048//modulation by virus of host morphology or physiology;GO:0050679//positive regulation of epithelial cell proliferation;GO:0071158//positive regulation of cell cycle arrest;GO:0007093//mitotic cell cycle checkpoint;GO:0043491//protein kinase B signaling;GO:0032270//positive regulation of cellular protein metabolic process;GO:0043029//T cell homeostasis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0031536//positive regulation of exit from mitosis;GO:0009817//defense response to fungus, incompatible interaction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050714//positive regulation of protein secretion;GO:0050777//negative regulation of immune response;GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0031065//positive regulation of histone deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030335//positive regulation of cell migration;GO:0006874//cellular calcium ion homeostasis;GO:0008156//negative regulation of DNA replication;GO:0043011//myeloid dendritic cell differentiation;GO:0001837//epithelial to mesenchymal transition;GO:0006796//phosphate-containing compound metabolic process;GO:0042552//myelination;GO:0007435//salivary gland morphogenesis;GO:0071549//cellular response to dexamethasone stimulus;GO:0046732//active induction of host immune response by virus;GO:0045786//negative regulation of cell cycle;GO:0048298//positive regulation of isotype switching to IgA isotypes;GO:0030168//platelet activation;GO:1901666//positive regulation of NAD+ ADP-ribosyltransferase activity;GO:0050921//positive regulation of chemotaxis;GO:0032930//positive regulation of superoxide anion generation;GO:0001933//negative regulation of protein phosphorylation;GO:0045066//regulatory T cell differentiation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030308//negative regulation of cell growth;GO:1900182//positive regulation of protein localization to nucleus;GO:0045930//negative regulation of mitotic cell cycle;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0010716//negative regulation of extracellular matrix disassembly;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0009790//embryo development;GO:0008284//positive regulation of cell proliferation;GO:0042482//positive regulation of odontogenesis;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0032740//positive regulation of interleukin-17 production;GO:0050680//negative regulation of epithelial cell proliferation;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0002062//chondrocyte differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060312//regulation of blood vessel remodeling;GO:0032801//receptor catabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043406//positive regulation of MAP kinase activity;GO:0002244//hematopoietic progenitor cell differentiation;GO:0060751//branch elongation involved in mammary gland duct branching;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0006611//protein export from nucleus;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0016202//regulation of striated muscle tissue development;GO:0051781//positive regulation of cell division;GO:0007183//SMAD protein complex assembly;GO:0006754//ATP biosynthetic process;GO:0042307//positive regulation of protein import into nucleus;GO:0010763//positive regulation of fibroblast migration;GO:0002028//regulation of sodium ion transport;GO:0035307//positive regulation of protein dephosphorylation;GO:0050765//negative regulation of phagocytosis;GO:0071407//cellular response to organic cyclic compound;GO:0007182//common-partner SMAD protein phosphorylation;GO:0007565//female pregnancy;GO:0009749//response to glucose;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0010629//negative regulation of gene expression;GO:0016049//cell growth;GO:0048565//digestive tract development;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:1901203//positive regulation of extracellular matrix assembly;GO:0009314//response to radiation;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0001666//response to hypoxia;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:1900126//negative regulation of hyaluronan biosynthetic process;GO:0006468//protein phosphorylation;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0033280//response to vitamin D;GO:0006954//inflammatory response;GO:0008354//germ cell migration;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060744//mammary gland branching involved in thelarche;GO:2000628//regulation of miRNA metabolic process;GO:0000165//MAPK cascade;GO:0060325//face morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0031100//organ regeneration;GO:0061035//regulation of cartilage development;GO:0042493//response to drug;GO:0030198//extracellular matrix organization;GO:0030279//negative regulation of ossification;GO:0007184//SMAD protein import into nucleus;GO:0045216//cell-cell junction organization;GO:0032943//mononuclear cell proliferation;GO:0010936//negative regulation of macrophage cytokine production",GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008083//growth factor activity;GO:0003823//antigen binding;GO:0019899//enzyme binding;GO:0047485//protein N-terminus binding;GO:0001948//glycoprotein binding;GO:0005114//type II transforming growth factor beta receptor binding,K13375//Osteoclast differentiation;Toxoplasmosis;Leishmaniasis;Hypertrophic cardiomyopathy (HCM);TGF-beta signaling pathway;Dilated cardiomyopathy;HTLV-I infection;Malaria;Chagas disease (American trypanosomiasis);Colorectal cancer;Renal cell carcinoma;Amoebiasis;Cell cycle;Chronic myeloid leukemia;Cytokine-cytokine receptor interaction;MAPK signaling pathway;Intestinal immune network for IgA production;Tuberculosis;Rheumatoid arthritis;Endocytosis;Pancreatic cancer;Pathways in cancer
7041,0,0,0,0,0,15,0,0,37,0,5,0,TGFB1I1;transforming growth factor beta 1 induced transcript 1,GO:0005925//focal adhesion;GO:0005622//intracellular;GO:0016363//nuclear matrix;GO:0005856//cytoskeleton;GO:0031012//extracellular matrix;GO:0005737//cytoplasm,"GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0030521//androgen receptor signaling pathway;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016055//Wnt signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006366//transcription from RNA polymerase II promoter;GO:0016331//morphogenesis of embryonic epithelium;GO:0009408//response to heat;GO:0007155//cell adhesion;GO:0045599//negative regulation of fat cell differentiation;GO:0030579//ubiquitin-dependent SMAD protein catabolic process;GO:0030855//epithelial cell differentiation;GO:0008285//negative regulation of cell proliferation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway",GO:0070411//I-SMAD binding;GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0048495//Roundabout binding,K05760//Focal adhesion;Leukocyte transendothelial migration;VEGF signaling pathway;Chemokine signaling pathway;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton
7042,0,0,23,0,0,16,0,0,26,0,0,0,"TGFB2;transforming growth factor, beta 2",GO:0031012//extracellular matrix;GO:0043025//neuronal cell body;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0030424//axon;GO:0005576//extracellular region;GO:0005768//endosome,GO:0051795//positive regulation of catagen;GO:0050777//negative regulation of immune response;GO:0050714//positive regulation of protein secretion;GO:0048663//neuron fate commitment;GO:0042637//catagen;GO:0006468//protein phosphorylation;GO:0097191//extrinsic apoptotic signaling pathway;GO:0010693//negative regulation of alkaline phosphatase activity;GO:0045778//positive regulation of ossification;GO:0001666//response to hypoxia;GO:0000902//cell morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0010936//negative regulation of macrophage cytokine production;GO:0045216//cell-cell junction organization;GO:0007184//SMAD protein import into nucleus;GO:0030198//extracellular matrix organization;GO:0007267//cell-cell signaling;GO:0031069//hair follicle morphogenesis;GO:0042493//response to drug;GO:0008219//cell death;GO:0060325//face morphogenesis;GO:0042060//wound healing;GO:0030593//neutrophil chemotaxis;GO:0045787//positive regulation of cell cycle;GO:0048103//somatic stem cell division;GO:0060038//cardiac muscle cell proliferation;GO:0051781//positive regulation of cell division;GO:0002576//platelet degranulation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0007596//blood coagulation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001525//angiogenesis;GO:0007507//heart development;GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0016049//cell growth;GO:0032147//activation of protein kinase activity;GO:0001654//eye development;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0030199//collagen fibril organization;GO:0032570//response to progesterone;GO:0050680//negative regulation of epithelial cell proliferation;GO:0042416//dopamine biosynthetic process;GO:0042476//odontogenesis;GO:0048566//embryonic digestive tract development;GO:0010634//positive regulation of epithelial cell migration;GO:0001974//blood vessel remodeling;GO:0048699//generation of neurons;GO:0008347//glial cell migration;GO:0007411//axon guidance;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0045726//positive regulation of integrin biosynthetic process;GO:0009611//response to wounding;GO:0023014//signal transduction by phosphorylation;GO:0007050//cell cycle arrest;GO:0003007//heart morphogenesis;GO:0030168//platelet activation;GO:0032909//regulation of transforming growth factor beta2 production;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0016477//cell migration;GO:0050778//positive regulation of immune response;GO:0045823//positive regulation of heart contraction;GO:0001502//cartilage condensation;GO:0051891//positive regulation of cardioblast differentiation;GO:0022601//menstrual cycle phase;GO:0030097//hemopoiesis;GO:0007435//salivary gland morphogenesis;GO:0048666//neuron development;GO:0070237//positive regulation of activation-induced cell death of T cells;GO:0010002//cardioblast differentiation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0009790//embryo development;GO:0008284//positive regulation of cell proliferation;GO:0001942//hair follicle development;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0043525//positive regulation of neuron apoptotic process,GO:0005102//receptor binding;GO:0001540//beta-amyloid binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008083//growth factor activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0004702//receptor signaling protein serine/threonine kinase activity,K13376//Toxoplasmosis;Osteoclast differentiation;Leishmaniasis;Hypertrophic cardiomyopathy (HCM);TGF-beta signaling pathway;Dilated cardiomyopathy;HTLV-I infection;Malaria;Chagas disease (American trypanosomiasis);Amoebiasis;Renal cell carcinoma;Colorectal cancer;Cell cycle;Cytokine-cytokine receptor interaction;Chronic myeloid leukemia;MAPK signaling pathway;Tuberculosis;Pancreatic cancer;Rheumatoid arthritis;Endocytosis;Pathways in cancer
7043,0,48,0,19,67,10,0,0,4,0,0,0,"TGFB3;transforming growth factor, beta 3",GO:0043025//neuronal cell body;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0030315//T-tubule;GO:0009986//cell surface;GO:0031012//extracellular matrix;GO:0005634//nucleus;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space,"GO:0032570//response to progesterone;GO:0060364//frontal suture morphogenesis;GO:0042476//odontogenesis;GO:0050714//positive regulation of protein secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0043627//response to estrogen;GO:0030879//mammary gland development;GO:0001666//response to hypoxia;GO:0045740//positive regulation of DNA replication;GO:0007184//SMAD protein import into nucleus;GO:0008156//negative regulation of DNA replication;GO:0010936//negative regulation of macrophage cytokine production;GO:0048286//lung alveolus development;GO:0045216//cell-cell junction organization;GO:0001701//in utero embryonic development;GO:0030198//extracellular matrix organization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060325//face morphogenesis;GO:0048702//embryonic neurocranium morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0030168//platelet activation;GO:0070483//detection of hypoxia;GO:0048839//inner ear development;GO:0030501//positive regulation of bone mineralization;GO:0051781//positive regulation of cell division;GO:0051491//positive regulation of filopodium assembly;GO:0043524//negative regulation of neuron apoptotic process;GO:0007568//aging;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0007435//salivary gland morphogenesis;GO:0022601//menstrual cycle phase;GO:0048565//digestive tract development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0007565//female pregnancy;GO:0034616//response to laminar fluid shear stress;GO:0043932//ossification involved in bone remodeling;GO:0016049//cell growth;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0008285//negative regulation of cell proliferation;GO:0060021//palate development;GO:0032967//positive regulation of collagen biosynthetic process",GO:0008083//growth factor activity;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0050431//transforming growth factor beta binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0005114//type II transforming growth factor beta receptor binding,K13377//TGF-beta signaling pathway;Dilated cardiomyopathy;HTLV-I infection;Chagas disease (American trypanosomiasis);Malaria;Hypertrophic cardiomyopathy (HCM);Leishmaniasis;Toxoplasmosis;Tuberculosis;Rheumatoid arthritis;Pancreatic cancer;Endocytosis;Pathways in cancer;Cell cycle;Colorectal cancer;Amoebiasis;Renal cell carcinoma;Cytokine-cytokine receptor interaction;Chronic myeloid leukemia;MAPK signaling pathway
7044,0,0,0,0,0,1,14,0,0,0,0,0,LEFTY2;left-right determination factor 2,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0031012//extracellular matrix,GO:0007596//blood coagulation;GO:0016049//cell growth;GO:0030168//platelet activation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0002576//platelet degranulation,GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0005160//transforming growth factor beta receptor binding,K04668//TGF-beta signaling pathway
7045,30,0,0,0,0,39,9,0,51,37,1,0,"TGFBI;transforming growth factor, beta-induced, 68kDa",GO:0031012//extracellular matrix;GO:0005802//trans-Golgi network;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005604//basement membrane;GO:0005615//extracellular space,GO:0007162//negative regulation of cell adhesion;GO:0008283//cell proliferation;GO:0002062//chondrocyte differentiation;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0007601//visual perception;GO:0001525//angiogenesis;GO:0050896//response to stimulus,GO:0005518//collagen binding;GO:0050840//extracellular matrix binding;GO:0005515//protein binding;GO:0005178//integrin binding,-
7046,0,0,0,1,6,33,0,0,25,55,0,0,"TGFBR1;transforming growth factor, beta receptor 1",GO:0005923//tight junction;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0070022//transforming growth factor beta receptor homodimeric complex;GO:0043235//receptor complex,"GO:0006468//protein phosphorylation;GO:0006915//apoptotic process;GO:0048705//skeletal system morphogenesis;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0001937//negative regulation of endothelial cell proliferation;GO:0008354//germ cell migration;GO:0043542//endothelial cell migration;GO:0060017//parathyroid gland development;GO:0048663//neuron fate commitment;GO:0043393//regulation of protein binding;GO:0070723//response to cholesterol;GO:0001824//blastocyst development;GO:0042060//wound healing;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0031396//regulation of protein ubiquitination;GO:0001837//epithelial to mesenchymal transition;GO:0006355//regulation of transcription, DNA-templated;GO:0048762//mesenchymal cell differentiation;GO:0032331//negative regulation of chondrocyte differentiation;GO:0048538//thymus development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060037//pharyngeal system development;GO:0001701//in utero embryonic development;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0048870//cell motility;GO:0018107//peptidyl-threonine phosphorylation;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0001501//skeletal system development;GO:0023014//signal transduction by phosphorylation;GO:0007050//cell cycle arrest;GO:0048844//artery morphogenesis;GO:0009791//post-embryonic development;GO:0009952//anterior/posterior pattern specification;GO:0051491//positive regulation of filopodium assembly;GO:0043066//negative regulation of apoptotic process;GO:0060021//palate development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0051272//positive regulation of cellular component movement;GO:0030307//positive regulation of cell growth;GO:0030199//collagen fibril organization;GO:0000186//activation of MAPKK activity;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001525//angiogenesis;GO:0001822//kidney development;GO:0007507//heart development;GO:0002088//lens development in camera-type eye;GO:0060391//positive regulation of SMAD protein import into nucleus;GO:0008284//positive regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0048701//embryonic cranial skeleton morphogenesis","GO:0004672//protein kinase activity;GO:0050431//transforming growth factor beta binding;GO:0070411//I-SMAD binding;GO:0005524//ATP binding;GO:0046332//SMAD binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity",K04674//TGF-beta signaling pathway;Chagas disease (American trypanosomiasis);Pathways in cancer;Pancreatic cancer;HTLV-I infection;Endocytosis;Adherens junction;Colorectal cancer;MAPK signaling pathway;Osteoclast differentiation;Cytokine-cytokine receptor interaction;Chronic myeloid leukemia
7047,0,1070,3,31,254,66,0,0,66,0,9,568,TGM4;transglutaminase 4,GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0031012//extracellular matrix;GO:0005737//cytoplasm,GO:0042628//mating plug formation;GO:0018149//peptide cross-linking,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding,-
7048,0,0,0,0,0,4,23,0,12,0,5,0,"TGFBR2;transforming growth factor, beta receptor II (70/80kDa)",GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0070022//transforming growth factor beta receptor homodimeric complex;GO:0043235//receptor complex;GO:0005901//caveola,GO:0006915//apoptotic process;GO:0009612//response to mechanical stimulus;GO:0010634//positive regulation of epithelial cell migration;GO:0007584//response to nutrient;GO:0006898//receptor-mediated endocytosis;GO:0002666//positive regulation of T cell tolerance induction;GO:0043627//response to estrogen;GO:0006468//protein phosphorylation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:1990086//lens fiber cell apoptotic process;GO:0060440//trachea formation;GO:0070723//response to cholesterol;GO:0018105//peptidyl-serine phosphorylation;GO:0051138//positive regulation of NK T cell differentiation;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0042060//wound healing;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060463//lung lobe morphogenesis;GO:0002651//positive regulation of tolerance induction to self antigen;GO:0045766//positive regulation of angiogenesis;GO:0001701//in utero embryonic development;GO:0042493//response to drug;GO:0031100//organ regeneration;GO:0043011//myeloid dendritic cell differentiation;GO:0001570//vasculogenesis;GO:0002663//positive regulation of B cell tolerance induction;GO:0060434//bronchus morphogenesis;GO:0035162//embryonic hemopoiesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0018107//peptidyl-threonine phosphorylation;GO:0042127//regulation of cell proliferation;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0007224//smoothened signaling pathway;GO:0007369//gastrulation;GO:0007568//aging;GO:0023014//signal transduction by phosphorylation;GO:0001569//patterning of blood vessels;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0007182//common-partner SMAD protein phosphorylation;GO:0007566//embryo implantation;GO:0060021//palate development;GO:0007420//brain development;GO:0060443//mammary gland morphogenesis;GO:0032147//activation of protein kinase activity;GO:0009749//response to glucose;GO:0008284//positive regulation of cell proliferation;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051216//cartilage development;GO:0048565//digestive tract development;GO:0007507//heart development;GO:0001568//blood vessel development;GO:0002088//lens development in camera-type eye,"GO:0005539//glycosaminoglycan binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005026//transforming growth factor beta receptor activity, type II;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0034714//type III transforming growth factor beta receptor binding;GO:0005524//ATP binding;GO:0034713//type I transforming growth factor beta receptor binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0046332//SMAD binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0050431//transforming growth factor beta binding",K04388//Transcriptional misregulation in cancer;TGF-beta signaling pathway;Chagas disease (American trypanosomiasis);Pathways in cancer;HTLV-I infection;Pancreatic cancer;Endocytosis;Adherens junction;Colorectal cancer;MAPK signaling pathway;Osteoclast differentiation;Cytokine-cytokine receptor interaction;Chronic myeloid leukemia
7049,0,0,0,0,2,17,47,35,106,81,5,0,"TGFBR3;transforming growth factor, beta receptor III",GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum,GO:0001837//epithelial to mesenchymal transition;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0031100//organ regeneration;GO:0001824//blastocyst development;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060347//heart trabecula formation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0060216//definitive hemopoiesis;GO:0043393//regulation of protein binding;GO:0060318//definitive erythrocyte differentiation;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0001666//response to hypoxia;GO:0032354//response to follicle-stimulating hormone;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001889//liver development;GO:0051271//negative regulation of cellular component movement;GO:0001568//blood vessel development;GO:0016049//cell growth;GO:0034695//response to prostaglandin E;GO:0007181//transforming growth factor beta receptor complex assembly;GO:0060021//palate development;GO:0030509//BMP signaling pathway;GO:0035556//intracellular signal transduction;GO:0006955//immune response;GO:0010633//negative regulation of epithelial cell migration;GO:0003007//heart morphogenesis;GO:0060038//cardiac muscle cell proliferation;GO:0016477//cell migration;GO:0034699//response to luteinizing hormone;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0060317//cardiac epithelial to mesenchymal transition,"GO:0005160//transforming growth factor beta receptor binding;GO:0046332//SMAD binding;GO:0005114//type II transforming growth factor beta receptor binding;GO:0070123//transforming growth factor beta receptor activity, type III;GO:0050431//transforming growth factor beta binding;GO:0030165//PDZ domain binding;GO:0017134//fibroblast growth factor binding;GO:0015026//coreceptor activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0048185//activin binding",-
705,0,0,0,0,0,0,4,0,34,0,0,0,BYSL;bystin-like,GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005730//nucleolus;GO:0045177//apical part of cell;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007155//cell adhesion;GO:0001829//trophectodermal cell differentiation;GO:0008283//cell proliferation;GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007565//female pregnancy",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
7050,100,1,34,13,51,6,0,261,22,0,53,0,TGIF1;TGFB-induced factor homeobox 1,GO:0005654//nucleoplasm,"GO:0060041//retina development in camera-type eye;GO:0001843//neural tube closure;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0007368//determination of left/right symmetry;GO:0007275//multicellular organismal development;GO:0010470//regulation of gastrulation;GO:0042493//response to drug;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0009953//dorsal/ventral pattern formation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0038092//nodal signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0048146//positive regulation of fibroblast proliferation;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation",GO:0070410//co-SMAD binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,K15613//Transcriptional misregulation in cancer
7051,22,0,0,0,0,0,0,0,21,0,20,0,TGM1;transglutaminase 1,GO:0001533//cornified envelope;GO:0031224//intrinsic component of membrane;GO:0005913//cell-cell adherens junction;GO:0070062//extracellular vesicular exosome,GO:0006464//cellular protein modification process;GO:0018149//peptide cross-linking;GO:0030216//keratinocyte differentiation;GO:0009887//organ morphogenesis;GO:0043163//cell envelope organization;GO:0031424//keratinization,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
7052,0,13,0,0,62,16,6,4,15,76,0,0,TGM2;transglutaminase 2,GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0050729//positive regulation of inflammatory response;GO:0060445//branching involved in salivary gland morphogenesis;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0043277//apoptotic cell clearance;GO:0018153//isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine;GO:0043065//positive regulation of apoptotic process;GO:0060662//salivary gland cavitation;GO:0032471//negative regulation of endoplasmic reticulum calcium ion concentration;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0051260//protein homooligomerization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045785//positive regulation of cell adhesion;GO:0001974//blood vessel remodeling,GO:0005525//GTP binding;GO:0019904//protein domain specific binding;GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K05625//Huntington's disease
7053,0,0,0,0,0,33,0,1,13,30,12,63,TGM3;transglutaminase 3,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,GO:0030216//keratinocyte differentiation;GO:0031069//hair follicle morphogenesis;GO:0051262//protein tetramerization;GO:0006464//cellular protein modification process;GO:0018149//peptide cross-linking;GO:0031424//keratinization;GO:0043163//cell envelope organization,"GO:0003824//catalytic activity;GO:0016746//transferase activity, transferring acyl groups;GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0005509//calcium ion binding",-
7054,0,0,0,0,0,11,0,0,12,0,10,0,TH;tyrosine hydroxylase,GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm;GO:0009898//cytoplasmic side of plasma membrane;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0030425//dendrite;GO:0043195//terminal bouton;GO:0033162//melanosome membrane;GO:0005634//nucleus;GO:0005790//smooth endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0043204//perikaryon,"GO:0014823//response to activity;GO:0009651//response to salt stress;GO:0045472//response to ether;GO:0009887//organ morphogenesis;GO:0051602//response to electrical stimulus;GO:0007507//heart development;GO:0007626//locomotory behavior;GO:0042418//epinephrine biosynthetic process;GO:0071333//cellular response to glucose stimulus;GO:0034641//cellular nitrogen compound metabolic process;GO:0031667//response to nutrient levels;GO:0051412//response to corticosterone;GO:0021987//cerebral cortex development;GO:0035176//social behavior;GO:0042755//eating behavior;GO:0006665//sphingolipid metabolic process;GO:0006585//dopamine biosynthetic process from tyrosine;GO:0032355//response to estradiol;GO:0007601//visual perception;GO:0003007//heart morphogenesis;GO:0007613//memory;GO:0048596//embryonic camera-type eye morphogenesis;GO:0042462//eye photoreceptor cell development;GO:0015842//synaptic vesicle amine transport;GO:0052314//phytoalexin metabolic process;GO:0010043//response to zinc ion;GO:0010259//multicellular organismal aging;GO:0007612//learning;GO:0045471//response to ethanol;GO:0046684//response to pyrethroid;GO:0006631//fatty acid metabolic process;GO:0009653//anatomical structure morphogenesis;GO:0008016//regulation of heart contraction;GO:0032496//response to lipopolysaccharide;GO:0018963//phthalate metabolic process;GO:0071287//cellular response to manganese ion;GO:0035690//cellular response to drug;GO:0033076//isoquinoline alkaloid metabolic process;GO:0044281//small molecule metabolic process;GO:0043473//pigmentation;GO:0042214//terpene metabolic process;GO:0042136//neurotransmitter biosynthetic process;GO:0001963//synaptic transmission, dopaminergic;GO:0007605//sensory perception of sound;GO:0071316//cellular response to nicotine;GO:0071363//cellular response to growth factor stimulus;GO:0042745//circadian sleep/wake cycle;GO:0043434//response to peptide hormone;GO:0042421//norepinephrine biosynthetic process;GO:0001666//response to hypoxia;GO:0055114//oxidation-reduction process;GO:0009635//response to herbicide;GO:0009414//response to water deprivation;GO:0016137//glycoside metabolic process;GO:0042416//dopamine biosynthetic process;GO:0007617//mating behavior;GO:0042423//catecholamine biosynthetic process;GO:0009416//response to light stimulus;GO:0001975//response to amphetamine",GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0016597//amino acid binding;GO:0035240//dopamine binding;GO:0008198//ferrous iron binding;GO:0019825//oxygen binding;GO:0034617//tetrahydrobiopterin binding;GO:0004511//tyrosine 3-monooxygenase activity;GO:0005515//protein binding;GO:0008199//ferric iron binding,K00501//Metabolic pathways;Tyrosine metabolism;Parkinson's disease;Amphetamine addiction;Cocaine addiction;Dopaminergic synapse;Alcoholism
7056,10,0,0,0,0,0,40,0,13,0,0,0,THBD;thrombomodulin,GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0051918//negative regulation of fibrinolysis;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0010544//negative regulation of platelet activation;GO:0007565//female pregnancy;GO:0051591//response to cAMP;GO:0030195//negative regulation of blood coagulation;GO:0007596//blood coagulation;GO:0032496//response to lipopolysaccharide;GO:0010165//response to X-ray,GO:0004872//receptor activity;GO:0005509//calcium ion binding;GO:0030246//carbohydrate binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K03907//Complement and coagulation cascades
7057,0,0,49,14,11,0,46,18,31,0,24,0,THBS1;thrombospondin 1,GO:0005577//fibrinogen complex;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0031012//extracellular matrix;GO:0031091//platelet alpha granule;GO:0016529//sarcoplasmic reticulum;GO:0031093//platelet alpha granule lumen;GO:0030141//secretory granule;GO:0005615//extracellular space,GO:0009612//response to mechanical stimulus;GO:0001666//response to hypoxia;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0071363//cellular response to growth factor stimulus;GO:0010759//positive regulation of macrophage chemotaxis;GO:0045727//positive regulation of translation;GO:0032026//response to magnesium ion;GO:0000187//activation of MAPK activity;GO:0033574//response to testosterone;GO:0030335//positive regulation of cell migration;GO:0010811//positive regulation of cell-substrate adhesion;GO:0030198//extracellular matrix organization;GO:0045766//positive regulation of angiogenesis;GO:0042493//response to drug;GO:0051895//negative regulation of focal adhesion assembly;GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0003417//growth plate cartilage development;GO:0051592//response to calcium ion;GO:0006986//response to unfolded protein;GO:0016525//negative regulation of angiogenesis;GO:0030194//positive regulation of blood coagulation;GO:0034976//response to endoplasmic reticulum stress;GO:0010763//positive regulation of fibroblast migration;GO:0002581//negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0002605//negative regulation of dendritic cell antigen processing and presentation;GO:0048266//behavioral response to pain;GO:0032695//negative regulation of interleukin-12 production;GO:0034605//cellular response to heat;GO:0009749//response to glucose;GO:0018149//peptide cross-linking;GO:0043032//positive regulation of macrophage activation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0010751//negative regulation of nitric oxide mediated signal transduction;GO:0001953//negative regulation of cell-matrix adhesion;GO:0032570//response to progesterone;GO:0001937//negative regulation of endothelial cell proliferation;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0010757//negative regulation of plasminogen activation;GO:0043652//engulfment of apoptotic cell;GO:0042327//positive regulation of phosphorylation;GO:0007155//cell adhesion;GO:0003151//outflow tract morphogenesis;GO:0016477//cell migration;GO:0007050//cell cycle arrest;GO:0030168//platelet activation;GO:0071356//cellular response to tumor necrosis factor;GO:0051918//negative regulation of fibrinolysis;GO:0010595//positive regulation of endothelial cell migration;GO:0006955//immune response;GO:0050921//positive regulation of chemotaxis;GO:0043066//negative regulation of apoptotic process;GO:0002544//chronic inflammatory response;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0003197//endocardial cushion development;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002040//sprouting angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0010754//negative regulation of cGMP-mediated signaling,GO:0008201//heparin binding;GO:0043394//proteoglycan binding;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding;GO:0001968//fibronectin binding;GO:0017134//fibroblast growth factor binding;GO:0042802//identical protein binding;GO:0050431//transforming growth factor beta binding;GO:0070052//collagen V binding;GO:0001948//glycoprotein binding;GO:0070051//fibrinogen binding;GO:0043236//laminin binding,K04659//Malaria;ECM-receptor interaction;Phagosome;p53 signaling pathway;Bladder cancer;Focal adhesion;TGF-beta signaling pathway
7058,68,0,0,4,7,68,33,2,83,102,2,0,THBS2;thrombospondin 2,GO:0031091//platelet alpha granule;GO:0005576//extracellular region;GO:0005604//basement membrane,GO:0007155//cell adhesion;GO:0051965//positive regulation of synapse assembly;GO:0016525//negative regulation of angiogenesis,GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0008201//heparin binding,K04659//Focal adhesion;TGF-beta signaling pathway;Bladder cancer;p53 signaling pathway;ECM-receptor interaction;Phagosome;Malaria
7059,0,0,56,1,11,5,0,46,35,0,0,0,THBS3;thrombospondin 3,GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm,GO:0003417//growth plate cartilage development;GO:0007160//cell-matrix adhesion;GO:0060346//bone trabecula formation;GO:0043931//ossification involved in bone maturation,GO:0005509//calcium ion binding;GO:0008201//heparin binding,K04659//Phagosome;ECM-receptor interaction;Malaria;TGF-beta signaling pathway;Focal adhesion;Bladder cancer;p53 signaling pathway
706,0,1,1,4,2,0,0,0,0,0,4,0,TSPO;translocator protein (18kDa),GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0032374//regulation of cholesterol transport;GO:0006626//protein targeting to mitochondrion;GO:0006820//anion transport;GO:0008283//cell proliferation;GO:0006915//apoptotic process;GO:0006783//heme biosynthetic process;GO:0008202//steroid metabolic process;GO:0006869//lipid transport;GO:0007268//synaptic transmission,GO:0015485//cholesterol binding;GO:0008503//benzodiazepine receptor activity,K05770//Neuroactive ligand-receptor interaction;HTLV-I infection
7060,45,0,0,0,0,54,8,0,73,0,3,0,THBS4;thrombospondin 4,GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0016529//sarcoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0005604//basement membrane,GO:0048771//tissue remodeling;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0016525//negative regulation of angiogenesis;GO:0006986//response to unfolded protein;GO:0051781//positive regulation of cell division;GO:0034976//response to endoplasmic reticulum stress;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0034103//regulation of tissue remodeling;GO:0051451//myoblast migration;GO:0071603//endothelial cell-cell adhesion;GO:0001938//positive regulation of endothelial cell proliferation;GO:0048266//behavioral response to pain,GO:0005509//calcium ion binding;GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0008201//heparin binding,K04659//Bladder cancer;p53 signaling pathway;TGF-beta signaling pathway;Focal adhesion;Malaria;Phagosome;ECM-receptor interaction
7062,166,0,0,0,9,9,17,0,45,0,2,0,TCHH;trichohyalin,GO:0005856//cytoskeleton,GO:0031424//keratinization,GO:0005509//calcium ion binding,-
7064,0,1,1,0,1,0,2,0,24,0,7,0,THOP1;thimet oligopeptidase 1,GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction;GO:0006508//proteolysis;GO:0006518//peptide metabolic process,GO:0042277//peptide binding;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K01392//Renin-angiotensin system;African trypanosomiasis
7066,158,0,0,0,0,0,18,2,12,0,1,0,THPO;thrombopoietin,GO:0005615//extracellular space,GO:0038163//thrombopoietin-mediated signaling pathway;GO:0030099//myeloid cell differentiation;GO:0030168//platelet activation;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0051897//positive regulation of protein kinase B signaling;GO:0007275//multicellular organismal development;GO:0001934//positive regulation of protein phosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0008283//cell proliferation;GO:0007596//blood coagulation,GO:0005179//hormone activity;GO:0005125//cytokine activity;GO:0008083//growth factor activity,K06854//Hematopoietic cell lineage
7067,0,2,0,20,44,5,0,31,15,123,40,0,"THRA;thyroid hormone receptor, alpha",GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0010831//positive regulation of myotube differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0001502//cartilage condensation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030878//thyroid gland development;GO:0030522//intracellular receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009755//hormone-mediated signaling pathway;GO:0017055//negative regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0009409//response to cold;GO:0008016//regulation of heart contraction;GO:0033032//regulation of myeloid cell apoptotic process;GO:2000143//negative regulation of DNA-templated transcription, initiation;GO:0010467//gene expression;GO:0042994//cytoplasmic sequestering of transcription factor;GO:0050994//regulation of lipid catabolic process;GO:0060509//Type I pneumocyte differentiation;GO:0001503//ossification;GO:0030218//erythrocyte differentiation;GO:0008050//female courtship behavior;GO:0002155//regulation of thyroid hormone mediated signaling pathway;GO:0007611//learning or memory;GO:0045925//positive regulation of female receptivity",GO:0032403//protein complex binding;GO:0019904//protein domain specific binding;GO:0070324//thyroid hormone binding;GO:0002153//steroid receptor RNA activator RNA binding;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0004887//thyroid hormone receptor activity;GO:0044212//transcription regulatory region DNA binding;GO:0017025//TBP-class protein binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,K05547//Neuroactive ligand-receptor interaction
7068,122,0,0,46,63,20,21,18,43,0,0,0,"THRB;thyroid hormone receptor, beta",GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm,"GO:0007605//sensory perception of sound;GO:0030522//intracellular receptor signaling pathway;GO:0060509//Type I pneumocyte differentiation;GO:0008050//female courtship behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008016//regulation of heart contraction;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007621//negative regulation of female receptivity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009887//organ morphogenesis;GO:0010467//gene expression",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0019899//enzyme binding;GO:0070324//thyroid hormone binding;GO:0003714//transcription corepressor activity;GO:0031490//chromatin DNA binding;GO:0043565//sequence-specific DNA binding;GO:0004887//thyroid hormone receptor activity;GO:0003677//DNA binding,K08362//Neuroactive ligand-receptor interaction
7070,3,0,0,0,0,19,0,0,2,0,0,0,THY1;Thy-1 cell surface antigen,GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0030426//growth cone;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0031362//anchored component of external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030336//negative regulation of cell migration;GO:0050852//T cell receptor signaling pathway;GO:0050771//negative regulation of axonogenesis;GO:0046549//retinal cone cell development;GO:0016337//single organismal cell-cell adhesion;GO:0007010//cytoskeleton organization;GO:0050870//positive regulation of T cell activation;GO:0032321//positive regulation of Rho GTPase activity;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0048041//focal adhesion assembly;GO:0001525//angiogenesis;GO:0006469//negative regulation of protein kinase activity;GO:0043547//positive regulation of GTPase activity;GO:0050860//negative regulation of T cell receptor signaling pathway,GO:0005515//protein binding;GO:0005178//integrin binding;GO:0019901//protein kinase binding;GO:0005100//Rho GTPase activator activity;GO:0034235//GPI anchor binding,K06514//Leukocyte transendothelial migration
7071,0,0,0,0,0,18,0,0,10,0,0,0,KLF10;Kruppel-like factor 10,GO:0005634//nucleus,"GO:1901653//cellular response to peptide;GO:0007267//cell-cell signaling;GO:0035019//somatic stem cell maintenance;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0009267//cellular response to starvation;GO:0008283//cell proliferation;GO:0042752//regulation of circadian rhythm;GO:0001501//skeletal system development;GO:0045672//positive regulation of osteoclast differentiation;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030282//bone mineralization;GO:0008285//negative regulation of cell proliferation",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001046//core promoter sequence-specific DNA binding,-
7072,0,28,1,8,0,34,0,79,27,0,0,0,TIA1;TIA1 cytotoxic granule-associated RNA binding protein,GO:0097165//nuclear stress granule;GO:0010494//cytoplasmic stress granule,"GO:0042036//negative regulation of cytokine biosynthetic process;GO:0006915//apoptotic process;GO:0048024//regulation of mRNA splicing, via spliceosome;GO:0017148//negative regulation of translation",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0017091//AU-rich element binding,-
7073,0,1,3,4,55,0,16,0,62,0,15,0,TIAL1;TIA1 cytotoxic granule-associated RNA binding protein-like 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0010494//cytoplasmic stress granule;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome,GO:0017145//stem cell division;GO:0008284//positive regulation of cell proliferation;GO:0007281//germ cell development;GO:0006952//defense response;GO:0006915//apoptotic process;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003723//RNA binding;GO:0017091//AU-rich element binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
7074,189,0,0,0,18,0,53,0,67,0,0,229,TIAM1;T-cell lymphoma invasion and metastasis 1,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0044291//cell-cell contact zone;GO:0005829//cytosol;GO:0005911//cell-cell junction,GO:0048013//ephrin receptor signaling pathway;GO:0016601//Rac protein signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0016477//cell migration;GO:0050772//positive regulation of axonogenesis;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0032855//positive regulation of Rac GTPase activity;GO:0007160//cell-matrix adhesion,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005057//receptor signaling protein activity;GO:0005543//phospholipid binding;GO:0046875//ephrin receptor binding,K05731//Regulation of actin cytoskeleton;Chemokine signaling pathway
7075,152,4,0,0,0,44,16,0,58,0,11,0,TIE1;tyrosine kinase with immunoglobulin-like and EGF-like domains 1,GO:0005887//integral component of plasma membrane,GO:0007498//mesoderm development;GO:0045026//plasma membrane fusion;GO:0030336//negative regulation of cell migration;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0001570//vasculogenesis;GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:0032526//response to retinoic acid;GO:0001701//in utero embryonic development;GO:0016525//negative regulation of angiogenesis,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity,-
7076,0,0,0,1,18,0,12,57,0,0,0,0,TIMP1;TIMP metallopeptidase inhibitor 1,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005604//basement membrane;GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen,GO:0007596//blood coagulation;GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0034097//response to cytokine;GO:0010951//negative regulation of endopeptidase activity;GO:0043434//response to peptide hormone;GO:2001044//regulation of integrin-mediated signaling pathway;GO:0002576//platelet degranulation;GO:0043066//negative regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:1901164//negative regulation of trophoblast cell migration;GO:0007568//aging;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization;GO:0030168//platelet activation;GO:0048553//negative regulation of metalloenzyme activity,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity;GO:0008191//metalloendopeptidase inhibitor activity;GO:0002020//protease binding,-
7077,0,0,0,0,0,1,45,26,23,0,0,0,TIMP2;TIMP metallopeptidase inhibitor 2,GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0031514//motile cilium;GO:0005604//basement membrane;GO:0005615//extracellular space,GO:0045861//negative regulation of proteolysis;GO:0043410//positive regulation of MAPK cascade;GO:0030198//extracellular matrix organization;GO:0042493//response to drug;GO:0045930//negative regulation of mitotic cell cycle;GO:0032487//regulation of Rap protein signal transduction;GO:0071310//cellular response to organic substance;GO:0008285//negative regulation of cell proliferation;GO:0045762//positive regulation of adenylate cyclase activity;GO:0007417//central nervous system development;GO:0007568//aging;GO:0022617//extracellular matrix disassembly;GO:0046580//negative regulation of Ras protein signal transduction;GO:0045666//positive regulation of neuron differentiation;GO:0034097//response to cytokine;GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005178//integrin binding;GO:0008191//metalloendopeptidase inhibitor activity;GO:0008047//enzyme activator activity,-
7078,175,0,0,0,0,17,1,0,41,0,0,1,TIMP3;TIMP metallopeptidase inhibitor 3,GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005604//basement membrane,GO:0051045//negative regulation of membrane protein ectodomain proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0007601//visual perception;GO:0071310//cellular response to organic substance,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008191//metalloendopeptidase inhibitor activity,-
7079,68,0,39,0,0,21,0,0,15,0,7,18,TIMP4;TIMP metallopeptidase inhibitor 4,GO:0030017//sarcomere;GO:0005615//extracellular space,GO:0043434//response to peptide hormone;GO:0007417//central nervous system development;GO:0042493//response to drug;GO:0042698//ovulation cycle;GO:0032496//response to lipopolysaccharide;GO:0034097//response to cytokine;GO:0010951//negative regulation of endopeptidase activity,GO:0008191//metalloendopeptidase inhibitor activity;GO:0046872//metal ion binding,-
708,0,0,0,6,101,0,27,2,0,0,0,0,"C1QBP;complement component 1, q subcomponent binding protein",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,"GO:0014065//phosphatidylinositol 3-kinase signaling;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0006351//transcription, DNA-templated;GO:0006955//immune response;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0006958//complement activation, classical pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0032695//negative regulation of interleukin-12 production;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:1901165//positive regulation of trophoblast cell migration;GO:0045087//innate immune response;GO:0051897//positive regulation of protein kinase B signaling;GO:0050687//negative regulation of defense response to virus;GO:0032689//negative regulation of interferon-gamma production;GO:0030449//regulation of complement activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0006915//apoptotic process;GO:0007596//blood coagulation;GO:0042256//mature ribosome assembly;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0043065//positive regulation of apoptotic process;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0070131//positive regulation of mitochondrial translation;GO:0016032//viral process;GO:0045785//positive regulation of cell adhesion;GO:0039536//negative regulation of RIG-I signaling pathway",GO:0005080//protein kinase C binding;GO:0003729//mRNA binding;GO:0003714//transcription corepressor activity;GO:0031690//adrenergic receptor binding;GO:0005515//protein binding;GO:0001849//complement component C1q binding;GO:0005540//hyaluronic acid binding;GO:0008134//transcription factor binding;GO:0030984//kininogen binding;GO:0097177//mitochondrial ribosome binding,K15414//Herpes simplex infection
7080,0,0,0,0,0,0,0,0,11,0,3,0,NKX2-1;NK2 homeobox 1,GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0048709//oligodendrocyte differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0001764//neuron migration;GO:0060486//Clara cell differentiation;GO:0060430//lung saccule development;GO:0060510//Type II pneumocyte differentiation;GO:0007626//locomotory behavior;GO:0021766//hippocampus development;GO:0021798//forebrain dorsal/ventral pattern formation;GO:0030336//negative regulation of cell migration;GO:0007420//brain development;GO:0042696//menarche;GO:0021877//forebrain neuron fate commitment;GO:0010628//positive regulation of gene expression;GO:0030878//thyroid gland development;GO:0042753//positive regulation of circadian rhythm;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006644//phospholipid metabolic process;GO:0048511//rhythmic process;GO:0009725//response to hormone;GO:0006366//transcription from RNA polymerase II promoter;GO:0021795//cerebral cortex cell migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0031128//developmental induction;GO:0010719//negative regulation of epithelial to mesenchymal transition;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021759//globus pallidus development;GO:0033327//Leydig cell differentiation;GO:0021983//pituitary gland development;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0048646//anatomical structure formation involved in morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0007492//endoderm development;GO:0007411//axon guidance;GO:0021892//cerebral cortex GABAergic interneuron differentiation",GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001047//core promoter binding;GO:0019899//enzyme binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,-
7083,0,31,0,4,11,0,0,87,39,0,1,0,"TK1;thymidine kinase 1, soluble",GO:0005829//cytosol,GO:0031667//response to nutrient levels;GO:0006206//pyrimidine nucleobase metabolic process;GO:0014856//skeletal muscle cell proliferation;GO:0006139//nucleobase-containing compound metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0006260//DNA replication;GO:0016310//phosphorylation;GO:0051414//response to cortisol;GO:0046688//response to copper ion;GO:0043097//pyrimidine nucleoside salvage;GO:0046104//thymidine metabolic process;GO:0051289//protein homotetramerization;GO:0001889//liver development;GO:0060138//fetal process involved in parturition;GO:0009636//response to toxic substance;GO:0044281//small molecule metabolic process;GO:0048565//digestive tract development;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process,GO:0004797//thymidine kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding;GO:0019206//nucleoside kinase activity;GO:0008270//zinc ion binding,K00857//Drug metabolism - other enzymes;Pyrimidine metabolism;ABC transporters;Metabolic pathways;Other glycan degradation
7084,0,25,0,1,10,3,13,0,0,0,2,0,"TK2;thymidine kinase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0016310//phosphorylation;GO:0044281//small molecule metabolic process;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0009165//nucleotide biosynthetic process;GO:0043097//pyrimidine nucleoside salvage;GO:0006260//DNA replication,GO:0004797//thymidine kinase activity;GO:0005524//ATP binding,K00857//Pyrimidine metabolism;Drug metabolism - other enzymes;Other glycan degradation;Metabolic pathways;ABC transporters
7086,110,0,26,0,16,0,24,4,103,0,22,1,TKT;transketolase,GO:0005777//peroxisome;GO:0005634//nucleus;GO:0031982//vesicle;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,"GO:0040008//regulation of growth;GO:0006098//pentose-phosphate shunt;GO:0006112//energy reserve metabolic process;GO:0046166//glyceraldehyde-3-phosphate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0009052//pentose-phosphate shunt, non-oxidative branch;GO:0005999//xylulose biosynthetic process;GO:0044281//small molecule metabolic process",GO:0048037//cofactor binding;GO:0004802//transketolase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding,K00615//Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Microbial metabolism in diverse environments;Salmonella infection;RNA degradation;Biosynthesis of ansamycins;Pentose phosphate pathway;Metabolic pathways
7087,0,0,0,0,0,31,0,0,22,0,0,0,"ICAM5;intercellular adhesion molecule 5, telencephalin",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006909//phagocytosis;GO:0016337//single organismal cell-cell adhesion,GO:0005515//protein binding,-
7088,0,0,0,0,5,35,20,0,20,0,38,0,"TLE1;transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:2000811//negative regulation of anoikis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009887//organ morphogenesis;GO:0010628//positive regulation of gene expression;GO:0007275//multicellular organismal development;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030178//negative regulation of Wnt signaling pathway;GO:0007219//Notch signaling pathway;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0008134//transcription factor binding;GO:0003682//chromatin binding,K04497//Wnt signaling pathway;Notch signaling pathway
7089,0,0,0,0,0,12,0,0,7,0,0,0,TLE2;transducin-like enhancer of split 2,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005615//extracellular space,"GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0009887//organ morphogenesis;GO:0007219//Notch signaling pathway;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway",GO:0005515//protein binding;GO:0003714//transcription corepressor activity,K04497//Wnt signaling pathway;Notch signaling pathway
7090,41,80,29,27,24,42,0,0,24,0,9,0,TLE3;transducin-like enhancer of split 3,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0009887//organ morphogenesis;GO:0007219//Notch signaling pathway;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,K04497//Wnt signaling pathway;Notch signaling pathway
7091,0,0,0,1,0,0,0,0,54,56,6,276,TLE4;transducin-like enhancer of split 4,GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0016055//Wnt signaling pathway;GO:0007219//Notch signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0070491//repressing transcription factor binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding,K04497//Notch signaling pathway;Wnt signaling pathway
7092,0,10,0,0,0,46,10,0,68,211,34,0,TLL1;tolloid-like 1,GO:0005576//extracellular region,GO:0006508//proteolysis;GO:0030198//extracellular matrix organization;GO:0001501//skeletal system development;GO:0030154//cell differentiation;GO:0022617//extracellular matrix disassembly,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005518//collagen binding;GO:0004222//metalloendopeptidase activity,-
7093,180,0,0,0,10,0,39,18,27,109,6,0,TLL2;tolloid-like 2,GO:0005576//extracellular region,GO:0022617//extracellular matrix disassembly;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0006508//proteolysis;GO:0007275//multicellular organismal development,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,-
7094,0,0,2,32,31,41,34,211,116,0,34,0,TLN1;talin 1,GO:0005815//microtubule organizing center;GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007596//blood coagulation;GO:0030866//cortical actin cytoskeleton organization;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006936//muscle contraction;GO:0044267//cellular protein metabolic process;GO:0006928//cellular component movement;GO:0070527//platelet aggregation;GO:0007411//axon guidance;GO:0002576//platelet degranulation;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0030168//platelet activation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007044//cell-substrate junction assembly;GO:0007043//cell-cell junction assembly,GO:0030274//LIM domain binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0017166//vinculin binding;GO:0005158//insulin receptor binding,K06271//HTLV-I infection;Focal adhesion
7095,0,32,0,22,76,0,0,0,63,0,0,0,SEC62;SEC62 homolog (S. cerevisiae),GO:0005791//rough endoplasmic reticulum;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006613//cotranslational protein targeting to membrane;GO:0006620//posttranslational protein targeting to membrane,GO:0004872//receptor activity;GO:0008565//protein transporter activity,K12275//Protein export;Protein processing in endoplasmic reticulum
7096,0,0,0,0,0,32,0,0,23,0,0,0,TLR1;toll-like receptor 1,GO:0005887//integral component of plasma membrane;GO:0035354//Toll-like receptor 1-Toll-like receptor 2 protein complex;GO:0005886//plasma membrane;GO:0030670//phagocytic vesicle membrane;GO:0016020//membrane,GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0034130//toll-like receptor 1 signaling pathway;GO:0042495//detection of triacyl bacterial lipopeptide;GO:0050707//regulation of cytokine secretion;GO:0006955//immune response;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0042116//macrophage activation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007165//signal transduction;GO:0006954//inflammatory response;GO:0045087//innate immune response,GO:0004872//receptor activity;GO:0004888//transmembrane signaling receptor activity;GO:0046982//protein heterodimerization activity,K05398//Toll-like receptor signaling pathway;Tuberculosis
7097,0,0,0,0,0,0,70,2,0,0,0,0,TLR2;toll-like receptor 2,GO:0044297//cell body;GO:0005737//cytoplasm;GO:0035355//Toll-like receptor 2-Toll-like receptor 6 protein complex;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0035354//Toll-like receptor 1-Toll-like receptor 2 protein complex;GO:0009986//cell surface;GO:0042995//cell projection;GO:0005887//integral component of plasma membrane,GO:0044130//negative regulation of growth of symbiont in host;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0032868//response to insulin;GO:0032760//positive regulation of tumor necrosis factor production;GO:0032733//positive regulation of interleukin-10 production;GO:0002224//toll-like receptor signaling pathway;GO:0032289//central nervous system myelin formation;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0002238//response to molecule of fungal origin;GO:0002282//microglial cell activation involved in immune response;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0032741//positive regulation of interleukin-18 production;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0032570//response to progesterone;GO:0007165//signal transduction;GO:0071221//cellular response to bacterial lipopeptide;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0030177//positive regulation of Wnt signaling pathway;GO:0042496//detection of diacyl bacterial lipopeptide;GO:0002752//cell surface pattern recognition receptor signaling pathway;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production;GO:0060907//positive regulation of macrophage cytokine production;GO:0006691//leukotriene metabolic process;GO:0071223//cellular response to lipoteichoic acid;GO:0052063//induction by symbiont of defense-related host nitric oxide production;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0002687//positive regulation of leukocyte migration;GO:0009636//response to toxic substance;GO:0006955//immune response;GO:0050715//positive regulation of cytokine secretion;GO:0042495//detection of triacyl bacterial lipopeptide;GO:0046209//nitric oxide metabolic process;GO:0032695//negative regulation of interleukin-12 production;GO:0071727//cellular response to triacyl bacterial lipopeptide;GO:0008285//negative regulation of cell proliferation;GO:0034142//toll-like receptor 4 signaling pathway;GO:0042892//chloramphenicol transport;GO:0071224//cellular response to peptidoglycan;GO:0050830//defense response to Gram-positive bacterium;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0007252//I-kappaB phosphorylation;GO:0071726//cellular response to diacyl bacterial lipopeptide;GO:0050729//positive regulation of inflammatory response;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032700//negative regulation of interleukin-17 production;GO:0032735//positive regulation of interleukin-12 production;GO:0032757//positive regulation of interleukin-8 production;GO:0070542//response to fatty acid;GO:0034123//positive regulation of toll-like receptor signaling pathway,GO:0042497//triacyl lipopeptide binding;GO:0004872//receptor activity;GO:0042498//diacyl lipopeptide binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0001875//lipopolysaccharide receptor activity;GO:0046982//protein heterodimerization activity;GO:0070891//lipoteichoic acid binding;GO:0008329//signaling pattern recognition receptor activity;GO:0042834//peptidoglycan binding,K10159//Amoebiasis;Measles;Herpes simplex infection;Toxoplasmosis;Leishmaniasis;Toll-like receptor signaling pathway;Legionellosis;Tuberculosis;Rheumatoid arthritis;Phagosome;Chagas disease (American trypanosomiasis);Malaria
7098,0,0,0,0,0,1,5,0,1,0,0,0,TLR3;toll-like receptor 3,GO:0036020//endolysosome membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm,GO:0045671//negative regulation of osteoclast differentiation;GO:0032735//positive regulation of interleukin-12 production;GO:0052033//pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response;GO:0050729//positive regulation of inflammatory response;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0008584//male gonad development;GO:0032757//positive regulation of interleukin-8 production;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0097527//necroptotic signaling pathway;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0007252//I-kappaB phosphorylation;GO:0034346//positive regulation of type III interferon production;GO:0043330//response to exogenous dsRNA;GO:0042742//defense response to bacterium;GO:0046330//positive regulation of JNK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035458//cellular response to interferon-beta;GO:0071360//cellular response to exogenous dsRNA;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0032722//positive regulation of chemokine production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032728//positive regulation of interferon-beta production;GO:0071260//cellular response to mechanical stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0032755//positive regulation of interleukin-6 production;GO:0051607//defense response to virus;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0071346//cellular response to interferon-gamma;GO:0007165//signal transduction;GO:0045356//positive regulation of interferon-alpha biosynthetic process;GO:0002224//toll-like receptor signaling pathway;GO:0006972//hyperosmotic response;GO:0009597//detection of virus;GO:0035690//cellular response to drug;GO:0002282//microglial cell activation involved in immune response;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0032760//positive regulation of tumor necrosis factor production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0004872//receptor activity;GO:0003725//double-stranded RNA binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K05401//Toll-like receptor signaling pathway;Influenza A;Hepatitis C;Herpes simplex infection
7099,0,0,0,0,1,12,0,48,36,0,0,0,TLR4;toll-like receptor 4,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0046696//lipopolysaccharide receptor complex;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0010008//endosome membrane,GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0060907//positive regulation of macrophage cytokine production;GO:0032727//positive regulation of interferon-alpha production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0006955//immune response;GO:0002322//B cell proliferation involved in immune response;GO:0032707//negative regulation of interleukin-23 production;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0042742//defense response to bacterium;GO:0045359//positive regulation of interferon-beta biosynthetic process;GO:0071222//cellular response to lipopolysaccharide;GO:0007252//I-kappaB phosphorylation;GO:0032720//negative regulation of tumor necrosis factor production;GO:0032609//interferon-gamma production;GO:0032497//detection of lipopolysaccharide;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0002537//nitric oxide production involved in inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0032715//negative regulation of interleukin-6 production;GO:0070430//positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0050707//regulation of cytokine secretion;GO:0071260//cellular response to mechanical stimulus;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production;GO:0042088//T-helper 1 type immune response;GO:0045416//positive regulation of interleukin-8 biosynthetic process;GO:0071223//cellular response to lipoteichoic acid;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0050829//defense response to Gram-negative bacterium;GO:0032728//positive regulation of interferon-beta production;GO:0032689//negative regulation of interferon-gamma production;GO:0032732//positive regulation of interleukin-1 production;GO:0046330//positive regulation of JNK cascade;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0050729//positive regulation of inflammatory response;GO:0045671//negative regulation of osteoclast differentiation;GO:0032700//negative regulation of interleukin-17 production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0032757//positive regulation of interleukin-8 production;GO:0070434//positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0010572//positive regulation of platelet activation;GO:0032729//positive regulation of interferon-gamma production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045348//positive regulation of MHC class II biosynthetic process;GO:0030890//positive regulation of B cell proliferation;GO:0032760//positive regulation of tumor necrosis factor production;GO:0042116//macrophage activation;GO:0032733//positive regulation of interleukin-10 production;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0032755//positive regulation of interleukin-6 production;GO:0016046//detection of fungus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051770//positive regulation of nitric-oxide synthase biosynthetic process;GO:0060729//intestinal epithelial structure maintenance;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0035666//TRIF-dependent toll-like receptor signaling pathway,GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0001875//lipopolysaccharide receptor activity;GO:0004872//receptor activity,K10160//Pertussis;Tuberculosis;Toll-like receptor signaling pathway;Influenza A;Salmonella infection;Rheumatoid arthritis;NF-kappa B signaling pathway;Phagosome;Amoebiasis;Legionellosis;Chagas disease (American trypanosomiasis);Malaria;Measles;Pathogenic Escherichia coli infection;Toxoplasmosis;Leishmaniasis
71,0,136,5,74,154,23,9,0,11,0,0,0,"ACTG1;actin, gamma 1",GO:0031941//filamentous actin;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005634//nucleus;GO:0030016//myofibril;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0016020//membrane;GO:0005856//cytoskeleton,GO:0045214//sarcomere organization;GO:0001895//retina homeostasis;GO:0007411//axon guidance;GO:0061024//membrane organization;GO:0034329//cell junction assembly;GO:0006928//cellular component movement;GO:0070527//platelet aggregation;GO:0045087//innate immune response;GO:0045216//cell-cell junction organization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0034332//adherens junction organization,GO:0005200//structural constituent of cytoskeleton;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K05692//Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Gastric acid secretion;Vibrio cholerae infection;Focal adhesion;Tight junction;Bacterial invasion of epithelial cells;Dilated cardiomyopathy;Shigellosis;Leukocyte transendothelial migration;Viral myocarditis;Adherens junction;Phototransduction - fly;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Phagosome;Salmonella infection;Influenza A
710,85,0,0,0,0,26,0,1,31,0,0,0,"SERPING1;serpin peptidase inhibitor, clade G (C1 inhibitor), member 1",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space,"GO:0030168//platelet activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0008015//blood circulation;GO:0045087//innate immune response;GO:0001869//negative regulation of complement activation, lectin pathway;GO:0006958//complement activation, classical pathway;GO:0002576//platelet degranulation;GO:0007596//blood coagulation;GO:0010951//negative regulation of endopeptidase activity;GO:0042730//fibrinolysis",GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity,K04001//Complement and coagulation cascades;Pertussis
7100,0,0,0,0,0,0,0,43,11,0,0,0,TLR5;toll-like receptor 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0071260//cellular response to mechanical stimulus;GO:0042742//defense response to bacterium;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034123//positive regulation of toll-like receptor signaling pathway;GO:0008584//male gonad development;GO:0032757//positive regulation of interleukin-8 production;GO:0002224//toll-like receptor signaling pathway;GO:0050707//regulation of cytokine secretion;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0006954//inflammatory response;GO:0045087//innate immune response,GO:0005149//interleukin-1 receptor binding;GO:0004888//transmembrane signaling receptor activity,K10168//Pathogenic Escherichia coli infection;Legionellosis;Toll-like receptor signaling pathway;Salmonella infection
7101,0,0,0,0,0,0,46,56,32,0,0,0,"NR2E1;nuclear receptor subfamily 2, group E, member 1",GO:0005654//nucleoplasm,GO:0045665//negative regulation of neuron differentiation;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060164//regulation of timing of neuron differentiation;GO:0030198//extracellular matrix organization;GO:0045165//cell fate commitment;GO:0045766//positive regulation of angiogenesis;GO:0008347//glial cell migration;GO:0048814//regulation of dendrite morphogenesis;GO:0021772//olfactory bulb development;GO:0007399//nervous system development;GO:0021542//dentate gyrus development;GO:0002118//aggressive behavior;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0021872//forebrain generation of neurons;GO:0021764//amygdala development;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0001662//behavioral fear response;GO:2000648//positive regulation of stem cell proliferation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0021895//cerebral cortex neuron differentiation;GO:0090049//regulation of cell migration involved in sprouting angiogenesis;GO:0021960//anterior commissure morphogenesis;GO:0060291//long-term synaptic potentiation;GO:0035176//social behavior;GO:0043401//steroid hormone mediated signaling pathway;GO:0021819//layer formation in cerebral cortex;GO:0060041//retina development in camera-type eye;GO:0048712//negative regulation of astrocyte differentiation;GO:0045787//positive regulation of cell cycle;GO:0035019//somatic stem cell maintenance;GO:0007601//visual perception,GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K08545//MAPK signaling pathway - fly
7102,0,0,0,0,0,3,0,0,0,0,0,0,TSPAN7;tetraspanin 7,GO:0005887//integral component of plasma membrane,GO:0016032//viral process,-,K06571//Transcriptional misregulation in cancer
7103,0,0,0,0,2,8,0,0,0,0,0,0,TSPAN8;tetraspanin 8,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0030195//negative regulation of blood coagulation,-,K06497//Lysosome;K06460//Hematopoietic cell lineage
7104,0,0,0,0,0,0,23,0,20,0,0,0,TM4SF4;transmembrane 4 L six family member 4,GO:0016021//integral component of membrane,GO:0042246//tissue regeneration,-,-
7105,0,33,3,0,0,0,0,57,43,0,0,0,TSPAN6;tetraspanin 6,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:1901223//negative regulation of NIK/NF-kappaB signaling,GO:0005515//protein binding;GO:0004871//signal transducer activity,K06571//Transcriptional misregulation in cancer
7106,0,0,0,0,0,0,0,0,2,142,0,0,TSPAN4;tetraspanin 4,GO:0031982//vesicle;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006461//protein complex assembly,GO:0003823//antigen binding;GO:0005178//integrin binding,K06497//Lysosome
7107,0,0,0,0,10,2,29,0,45,0,0,0,GPR137B;G protein-coupled receptor 137B,GO:0005887//integral component of plasma membrane;GO:0005765//lysosomal membrane;GO:0016020//membrane,-,-,-
7108,0,0,0,0,1,0,0,51,0,0,0,0,TM7SF2;transmembrane 7 superfamily member 2,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0043235//receptor complex;GO:0005783//endoplasmic reticulum,GO:0006695//cholesterol biosynthetic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process,GO:0050613//delta14-sterol reductase activity,K00222//Metabolic pathways;Steroid biosynthesis;Biosynthesis of secondary metabolites
7109,0,15,0,20,68,0,35,13,65,0,3,1,TRAPPC10;trafficking protein particle complex 10,GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,GO:0035725//sodium ion transmembrane transport;GO:0006814//sodium ion transport;GO:0016192//vesicle-mediated transport,GO:0015081//sodium ion transmembrane transporter activity;GO:0005515//protein binding,-
7110,0,0,1,55,148,4,14,0,31,0,6,0,TMF1;TATA element modulatory factor 1,GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005634//nucleus,"GO:0061136//regulation of proteasomal protein catabolic process;GO:0010629//negative regulation of gene expression;GO:0032275//luteinizing hormone secretion;GO:0033327//Leydig cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0001819//positive regulation of cytokine production;GO:0007289//spermatid nucleus differentiation;GO:0001675//acrosome assembly;GO:0042742//defense response to bacterium;GO:0043066//negative regulation of apoptotic process;GO:2000845//positive regulation of testosterone secretion;GO:0071407//cellular response to organic cyclic compound;GO:0030317//sperm motility",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003712//transcription cofactor activity,K11447//Transcriptional misregulation in cancer;K12478//Endocytosis;Phagosome;Tuberculosis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
7111,45,76,158,260,503,0,0,60,29,85,184,0,TMOD1;tropomodulin 1,GO:0008180//COP9 signalosome;GO:0030863//cortical cytoskeleton;GO:0030016//myofibril;GO:0016020//membrane;GO:0005829//cytosol,GO:0030049//muscle filament sliding;GO:0008344//adult locomotory behavior;GO:0030239//myofibril assembly,GO:0005523//tropomyosin binding;GO:0003779//actin binding,-
7112,0,30,0,7,28,15,43,48,17,0,13,0,TMPO;thymopoietin,GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0031965//nuclear membrane;GO:0000785//chromatin;GO:0005637//nuclear inner membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,"GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding;GO:0005521//lamin binding,K08860//Protein processing in endoplasmic reticulum;Herpes simplex infection;Hepatitis C;Alzheimer's disease;Measles;Epstein-Barr virus infection;Influenza A;K09188//Lysine degradation;K11447//Transcriptional misregulation in cancer;K10592//Ubiquitin mediated proteolysis;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways
7113,0,117,7,105,647,8,0,71,52,0,18,0,"TMPRSS2;transmembrane protease, serine 2",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0006508//proteolysis;GO:0016540//protein autoprocessing;GO:0046598//positive regulation of viral entry into host cell;GO:0006898//receptor-mediated endocytosis,GO:0005044//scavenger receptor activity;GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K09633//Influenza A;Transcriptional misregulation in cancer
7114,0,22,0,62,31,1,0,0,12,0,0,0,"TMSB4X;thymosin beta 4, X-linked",GO:0005856//cytoskeleton;GO:0005576//extracellular region;GO:0031093//platelet alpha granule lumen,GO:0002576//platelet degranulation;GO:0042989//sequestering of actin monomers;GO:0030168//platelet activation;GO:0030036//actin cytoskeleton organization;GO:0007596//blood coagulation,GO:0003779//actin binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K05764//Regulation of actin cytoskeleton
712,0,0,0,0,0,0,0,54,0,0,12,0,"C1QA;complement component 1, q subcomponent, A chain",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005581//collagen trimer;GO:0005602//complement component C1 complex,"GO:0045087//innate immune response;GO:0006956//complement activation;GO:0007267//cell-cell signaling;GO:0006958//complement activation, classical pathway",GO:0005515//protein binding,K03986//Complement and coagulation cascades;Pertussis;Staphylococcus aureus infection;Chagas disease (American trypanosomiasis);Prion diseases;Systemic lupus erythematosus
7122,0,0,0,0,0,0,0,2,28,0,11,0,CLDN5;claudin 5,GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005911//cell-cell junction;GO:0033270//paranode region of axon;GO:0043220//Schmidt-Lanterman incisure,GO:0042552//myelination;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Cell adhesion molecules (CAMs);Tight junction;Hepatitis C
7123,0,0,0,0,6,0,0,0,0,0,0,0,"CLEC3B;C-type lectin domain family 3, member B",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0001652//granular component;GO:0005737//cytoplasm;GO:0031012//extracellular matrix,GO:0010756//positive regulation of plasminogen activation;GO:0001501//skeletal system development;GO:0001503//ossification;GO:0071310//cellular response to organic substance;GO:0030282//bone mineralization;GO:0071560//cellular response to transforming growth factor beta stimulus,GO:0036143//kringle domain binding;GO:0005509//calcium ion binding;GO:0008201//heparin binding;GO:0030246//carbohydrate binding,K10068//Phagosome;K12589//RNA degradation
7125,0,0,0,0,0,0,0,0,3,0,0,0,TNNC2;troponin C type 2 (fast),GO:0005829//cytosol;GO:0005861//troponin complex,GO:0030049//muscle filament sliding;GO:0006937//regulation of muscle contraction;GO:0003009//skeletal muscle contraction,GO:0005509//calcium ion binding;GO:0003779//actin binding,K12042//Calcium signaling pathway
7126,0,231,97,106,225,9,0,40,7,0,143,0,"TNFAIP1;tumor necrosis factor, alpha-induced protein 1 (endothelial)",GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005768//endosome;GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0009790//embryo development;GO:0016477//cell migration;GO:0051260//protein homooligomerization;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043149//stress fiber assembly;GO:0006955//immune response;GO:0006915//apoptotic process;GO:0045740//positive regulation of DNA replication;GO:0035024//negative regulation of Rho protein signal transduction;GO:0006260//DNA replication;GO:0016567//protein ubiquitination,GO:0019904//protein domain specific binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0017049//GTP-Rho binding,-
7127,0,0,0,0,0,31,0,56,36,45,0,0,"TNFAIP2;tumor necrosis factor, alpha-induced protein 2",GO:0005615//extracellular space;GO:0000145//exocyst,GO:0030154//cell differentiation;GO:0006887//exocytosis;GO:0001525//angiogenesis,-,K06110//Tight junction
7128,41,0,0,1,9,8,21,65,85,32,6,0,"TNFAIP3;tumor necrosis factor, alpha-induced protein 3",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0045779//negative regulation of bone resorption;GO:0071222//cellular response to lipopolysaccharide;GO:0050691//regulation of defense response to virus by host;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0035871//protein K11-linked deubiquitination;GO:0045824//negative regulation of innate immune response;GO:0032720//negative regulation of tumor necrosis factor production;GO:2000349//negative regulation of CD40 signaling pathway;GO:0072573//tolerance induction to lipopolysaccharide;GO:0045087//innate immune response;GO:0061043//regulation of vascular wound healing;GO:0051259//protein oligomerization;GO:0032703//negative regulation of interleukin-2 production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0002634//regulation of germinal center formation;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0032715//negative regulation of interleukin-6 production;GO:0006954//inflammatory response;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0050728//negative regulation of inflammatory response;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0006508//proteolysis;GO:0070936//protein K48-linked ubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0090291//negative regulation of osteoclast proliferation;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0006915//apoptotic process;GO:0034140//negative regulation of toll-like receptor 3 signaling pathway;GO:0071108//protein K48-linked deubiquitination;GO:0045732//positive regulation of protein catabolic process;GO:0016579//protein deubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0050869//negative regulation of B cell activation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0001922//B-1 B cell homeostasis;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0070301//cellular response to hydrogen peroxide;GO:0070536//protein K63-linked deubiquitination",GO:0003677//DNA binding;GO:0016874//ligase activity;GO:0043621//protein self-association;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0002020//protease binding;GO:0004221//ubiquitin thiolesterase activity;GO:0043130//ubiquitin binding,K11859//NF-kappa B signaling pathway;Measles;NOD-like receptor signaling pathway;Epstein-Barr virus infection
713,0,0,0,0,0,0,25,0,0,0,0,0,"C1QB;complement component 1, q subcomponent, B chain",GO:0005602//complement component C1 complex;GO:0005581//collagen trimer;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,"GO:0006958//complement activation, classical pathway;GO:0048839//inner ear development;GO:0045087//innate immune response;GO:0006956//complement activation",GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K03987//Prion diseases;Systemic lupus erythematosus;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades
7130,0,0,0,0,0,4,0,0,10,0,0,0,"TNFAIP6;tumor necrosis factor, alpha-induced protein 6",-,GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response,GO:0005540//hyaluronic acid binding,K14616//Vitamin digestion and absorption
7132,0,1,0,0,0,0,35,69,10,99,0,0,"TNFRSF1A;tumor necrosis factor receptor superfamily, member 1A",GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0045121//membrane raft;GO:0005634//nucleus;GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0030424//axon;GO:0005615//extracellular space,"GO:0009611//response to wounding;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0016032//viral process;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042511//positive regulation of tyrosine phosphorylation of Stat1 protein;GO:0032715//negative regulation of interleukin-6 production;GO:0033013//tetrapyrrole metabolic process;GO:0050728//negative regulation of inflammatory response;GO:0097190//apoptotic signaling pathway;GO:0051291//protein heterooligomerization;GO:0019221//cytokine-mediated signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0043200//response to amino acid;GO:0050729//positive regulation of inflammatory response;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0006693//prostaglandin metabolic process;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043279//response to alkaloid;GO:0045766//positive regulation of angiogenesis;GO:0010629//negative regulation of gene expression;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0042742//defense response to bacterium;GO:0045471//response to ethanol;GO:0043066//negative regulation of apoptotic process;GO:0032496//response to lipopolysaccharide;GO:0071392//cellular response to estradiol stimulus",GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0043120//tumor necrosis factor binding;GO:0002020//protease binding;GO:0032403//protein complex binding,K03158//Tuberculosis;Influenza A;Chagas disease (American trypanosomiasis);NF-kappa B signaling pathway;HTLV-I infection;Osteoclast differentiation;Toxoplasmosis;Apoptosis;Adipocytokine signaling pathway;Herpes simplex infection;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Hepatitis C;Alzheimer's disease;Cytokine-cytokine receptor interaction
7133,0,0,0,0,0,0,0,0,6,0,2,0,"TNFRSF1B;tumor necrosis factor receptor superfamily, member 1B",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0016021//integral component of membrane;GO:0043025//neuronal cell body;GO:0043196//varicosity,GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0071363//cellular response to growth factor stimulus;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0050728//negative regulation of inflammatory response;GO:0097191//extrinsic apoptotic signaling pathway;GO:0006955//immune response;GO:0050779//RNA destabilization;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0006954//inflammatory response;GO:0007568//aging,GO:0031625//ubiquitin protein ligase binding;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding,K05141//Cytokine-cytokine receptor interaction;Amyotrophic lateral sclerosis (ALS);Adipocytokine signaling pathway
7134,0,0,0,0,0,11,11,0,0,0,0,0,TNNC1;troponin C type 1 (slow),GO:0005730//nucleolus;GO:0005861//troponin complex;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005634//nucleus,GO:0006937//regulation of muscle contraction;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0043462//regulation of ATPase activity;GO:0032972//regulation of muscle filament sliding speed;GO:0060048//cardiac muscle contraction;GO:0030049//muscle filament sliding;GO:0010038//response to metal ion;GO:0002086//diaphragm contraction,GO:0031014//troponin T binding;GO:0042803//protein homodimerization activity;GO:0031013//troponin I binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0051015//actin filament binding;GO:0048306//calcium-dependent protein binding,K05865//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Calcium signaling pathway;Cardiac muscle contraction
7135,91,192,0,244,68,0,3,0,11,29,257,0,"TNNI1;troponin I type 1 (skeletal, slow)",GO:0005861//troponin complex;GO:0005829//cytosol,GO:0030049//muscle filament sliding;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0006942//regulation of striated muscle contraction,GO:0046872//metal ion binding;GO:0003779//actin binding,-
7136,0,0,0,0,0,0,24,0,0,0,0,0,"TNNI2;troponin I type 2 (skeletal, fast)",GO:0005634//nucleus;GO:0005861//troponin complex;GO:0005829//cytosol,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0030049//muscle filament sliding;GO:0003009//skeletal muscle contraction",GO:0005515//protein binding;GO:0031014//troponin T binding;GO:0003779//actin binding,-
7137,0,0,0,0,0,13,0,0,0,0,0,0,TNNI3;troponin I type 3 (cardiac),GO:0030017//sarcomere;GO:0005861//troponin complex;GO:0005829//cytosol,GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060047//heart contraction;GO:0032780//negative regulation of ATPase activity;GO:0001980//regulation of systemic arterial blood pressure by ischemic conditions;GO:0001570//vasculogenesis;GO:0007507//heart development;GO:0006940//regulation of smooth muscle contraction;GO:0030049//muscle filament sliding;GO:0006874//cellular calcium ion homeostasis;GO:0060048//cardiac muscle contraction,GO:0003779//actin binding;GO:0019855//calcium channel inhibitor activity;GO:0031014//troponin T binding;GO:0019904//protein domain specific binding;GO:0030172//troponin C binding;GO:0019901//protein kinase binding;GO:0048306//calcium-dependent protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K12044//Cardiac muscle contraction;Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
7138,6,0,0,0,0,0,1,3,21,0,0,0,"TNNT1;troponin T type 1 (skeletal, slow)",GO:0005861//troponin complex;GO:0005829//cytosol,GO:0030049//muscle filament sliding;GO:0045932//negative regulation of muscle contraction;GO:0031444//slow-twitch skeletal muscle fiber contraction;GO:0003009//skeletal muscle contraction,GO:0005523//tropomyosin binding;GO:0031014//troponin T binding,-
7139,32,0,25,0,0,0,21,0,35,0,2,0,TNNT2;troponin T type 2 (cardiac),GO:0005829//cytosol;GO:0005861//troponin complex;GO:0005865//striated muscle thin filament;GO:0030017//sarcomere,GO:0006200//ATP catabolic process;GO:0032781//positive regulation of ATPase activity;GO:0030049//muscle filament sliding;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0051592//response to calcium ion;GO:0045214//sarcomere organization;GO:0032780//negative regulation of ATPase activity;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0006937//regulation of muscle contraction;GO:0008016//regulation of heart contraction,GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005523//tropomyosin binding;GO:0030172//troponin C binding;GO:0016887//ATPase activity;GO:0031013//troponin I binding,K12045//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction
714,0,0,0,0,0,0,0,57,0,0,0,0,"C1QC;complement component 1, q subcomponent, C chain",GO:0005581//collagen trimer;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,"GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response;GO:0030853//negative regulation of granulocyte differentiation;GO:0006956//complement activation;GO:0006955//immune response;GO:0045650//negative regulation of macrophage differentiation",-,K03988//Complement and coagulation cascades;Pertussis;Staphylococcus aureus infection;Systemic lupus erythematosus;Prion diseases;Chagas disease (American trypanosomiasis)
7140,0,0,0,0,0,0,0,0,10,0,0,0,"TNNT3;troponin T type 3 (skeletal, fast)",GO:0005861//troponin complex;GO:0005829//cytosol,GO:0006942//regulation of striated muscle contraction;GO:0006200//ATP catabolic process;GO:0043462//regulation of ATPase activity;GO:0003009//skeletal muscle contraction;GO:0030049//muscle filament sliding,GO:0031013//troponin I binding;GO:0030899//calcium-dependent ATPase activity;GO:0030172//troponin C binding;GO:0048306//calcium-dependent protein binding;GO:0005523//tropomyosin binding;GO:0003779//actin binding,-
7142,0,0,0,0,0,0,0,0,19,0,0,0,TNP2;transition protein 2 (during histone to protamine replacement),GO:0005634//nucleus;GO:0000786//nucleosome,GO:0007275//multicellular organismal development;GO:0030317//sperm motility;GO:0007341//penetration of zona pellucida;GO:0007283//spermatogenesis;GO:0007340//acrosome reaction;GO:0030154//cell differentiation;GO:0007339//binding of sperm to zona pellucida,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7143,0,0,0,0,0,2,14,0,20,18,6,0,TNR;tenascin R,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0072534//perineuronal net;GO:0005737//cytoplasm,"GO:0035641//locomotory exploration behavior;GO:0022408//negative regulation of cell-cell adhesion;GO:0007158//neuron cell-cell adhesion;GO:0051971//positive regulation of transmission of nerve impulse;GO:0048692//negative regulation of axon extension involved in regeneration;GO:0030198//extracellular matrix organization;GO:0050885//neuromuscular process controlling balance;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0007155//cell adhesion;GO:0008306//associative learning;GO:0050808//synapse organization;GO:0007411//axon guidance;GO:0060291//long-term synaptic potentiation;GO:0050805//negative regulation of synaptic transmission;GO:0022029//telencephalon cell migration",-,K06252//ECM-receptor interaction;Focal adhesion
7145,0,0,0,0,26,10,3,32,73,0,6,0,TNS1;tensin 1,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005925//focal adhesion,GO:0010761//fibroblast migration;GO:0007044//cell-substrate junction assembly,GO:0003779//actin binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K01110//Melanoma;Endometrial cancer;Focal adhesion;Inositol phosphate metabolism;p53 signaling pathway;Glioma;Tight junction;Phosphatidylinositol signaling system;Pathways in cancer;Small cell lung cancer;Prostate cancer;K00665//Fatty acid biosynthesis;Metabolic pathways;Insulin signaling pathway
7148,3,0,0,0,0,0,0,1,2,0,0,41,TNXB;tenascin XB,GO:0005615//extracellular space;GO:0005583//fibrillar collagen trimer;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0006641//triglyceride metabolic process;GO:0016337//single organismal cell-cell adhesion;GO:0006631//fatty acid metabolic process;GO:0032963//collagen metabolic process;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0030036//actin cytoskeleton organization;GO:0030199//collagen fibril organization;GO:0048251//elastic fiber assembly;GO:0043506//regulation of JUN kinase activity;GO:0043206//extracellular fibril organization,GO:0005518//collagen binding;GO:0005178//integrin binding;GO:0008201//heparin binding,K06252//ECM-receptor interaction;Focal adhesion
715,0,0,0,0,0,2,0,80,6,0,2,0,"C1R;complement component 1, r subcomponent",GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0072562//blood microparticle,"GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0006955//immune response;GO:0006956//complement activation",GO:0005509//calcium ion binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0008236//serine-type peptidase activity,K01330//Complement and coagulation cascades;Pertussis;Phagosome;Staphylococcus aureus infection;Systemic lupus erythematosus
7150,0,83,0,36,135,15,15,63,17,0,0,0,TOP1;topoisomerase (DNA) I,GO:0043204//perikaryon;GO:0005730//nucleolus;GO:0031298//replication fork protection complex;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0000228//nuclear chromosome;GO:0005654//nucleoplasm,GO:0006200//ATP catabolic process;GO:0016310//phosphorylation;GO:0016032//viral process;GO:0042493//response to drug;GO:0007059//chromosome segregation;GO:0040016//embryonic cleavage;GO:0006265//DNA topological change;GO:0006260//DNA replication;GO:0012501//programmed cell death;GO:0006338//chromatin remodeling,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003918//DNA topoisomerase type II (ATP-hydrolyzing) activity;GO:0003677//DNA binding;GO:0003917//DNA topoisomerase type I activity;GO:0003682//chromatin binding,-
7153,0,0,0,0,0,36,75,0,52,0,0,304,TOP2A;topoisomerase (DNA) II alpha 170kDa,GO:0019035//viral integration complex;GO:0000228//nuclear chromosome;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0009330//DNA topoisomerase complex (ATP-hydrolyzing);GO:0009295//nucleoid;GO:0000793//condensed chromosome;GO:0005634//nucleus;GO:0005814//centriole;GO:0005730//nucleolus,GO:0045870//positive regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0000278//mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0006265//DNA topological change;GO:0007059//chromosome segregation;GO:0006268//DNA unwinding involved in DNA replication;GO:0006200//ATP catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040016//embryonic cleavage;GO:0000819//sister chromatid segregation;GO:0000712//resolution of meiotic recombination intermediates;GO:0006312//mitotic recombination;GO:0006266//DNA ligation;GO:0044774//mitotic DNA integrity checkpoint;GO:0002244//hematopoietic progenitor cell differentiation;GO:0030263//apoptotic chromosome condensation;GO:0045070//positive regulation of viral genome replication,"GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008094//DNA-dependent ATPase activity;GO:0000287//magnesium ion binding;GO:0003918//DNA topoisomerase type II (ATP-hydrolyzing) activity;GO:0005080//protein kinase C binding;GO:0042826//histone deacetylase binding;GO:0008144//drug binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0043130//ubiquitin binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0008301//DNA binding, bending;GO:0019899//enzyme binding",-
7155,94,81,1,114,304,0,69,81,0,0,0,1031,TOP2B;topoisomerase (DNA) II beta 180kDa,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000792//heterochromatin;GO:0009330//DNA topoisomerase complex (ATP-hydrolyzing);GO:0009295//nucleoid;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0007409//axonogenesis;GO:0006268//DNA unwinding involved in DNA replication;GO:0044774//mitotic DNA integrity checkpoint;GO:0006200//ATP catabolic process;GO:0006265//DNA topological change;GO:0030900//forebrain development;GO:0000819//sister chromatid segregation;GO:0001764//neuron migration;GO:0006312//mitotic recombination;GO:0000712//resolution of meiotic recombination intermediates,"GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0008022//protein C-terminus binding;GO:0003918//DNA topoisomerase type II (ATP-hydrolyzing) activity;GO:0005080//protein kinase C binding;GO:0042826//histone deacetylase binding;GO:0008301//DNA binding, bending;GO:0005524//ATP binding;GO:0003682//chromatin binding;GO:0019899//enzyme binding",-
7156,0,0,0,0,9,18,0,0,13,0,1,2,TOP3A;topoisomerase (DNA) III alpha,GO:0005634//nucleus;GO:0005694//chromosome;GO:0016605//PML body,GO:0006265//DNA topological change;GO:0007126//meiotic nuclear division,GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003917//DNA topoisomerase type I activity,K03165//Homologous recombination;Fanconi anemia pathway
7157,0,28,3,3,23,20,0,30,29,0,8,0,TP53;tumor protein p53,GO:0005783//endoplasmic reticulum;GO:0043234//protein complex;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016363//nuclear matrix;GO:0005669//transcription factor TFIID complex;GO:0005654//nucleoplasm;GO:0016604//nuclear body;GO:0005737//cytoplasm;GO:0005657//replication fork;GO:0005759//mitochondrial matrix;GO:0016605//PML body;GO:0005730//nucleolus;GO:0000785//chromatin;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0071850//mitotic cell cycle arrest;GO:0002326//B cell lineage commitment;GO:0071479//cellular response to ionizing radiation;GO:0006461//protein complex assembly;GO:0071158//positive regulation of cell cycle arrest;GO:0009651//response to salt stress;GO:1901525//negative regulation of macromitophagy;GO:0090403//oxidative stress-induced premature senescence;GO:0008283//cell proliferation;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006284//base-excision repair;GO:0016032//viral process;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0007596//blood coagulation;GO:0006289//nucleotide-excision repair;GO:0006355//regulation of transcription, DNA-templated;GO:0071456//cellular response to hypoxia;GO:0008156//negative regulation of DNA replication;GO:0021549//cerebellum development;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0010666//positive regulation of cardiac muscle cell apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0034644//cellular response to UV;GO:1902108//regulation of mitochondrial membrane permeability involved in apoptotic process;GO:0051262//protein tetramerization;GO:0035690//cellular response to drug;GO:0042149//cellular response to glucose starvation;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0046902//regulation of mitochondrial membrane permeability;GO:0006302//double-strand break repair;GO:0031065//positive regulation of histone deacetylation;GO:0006974//cellular response to DNA damage stimulus;GO:0051097//negative regulation of helicase activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035794//positive regulation of mitochondrial membrane permeability;GO:0001836//release of cytochrome c from mitochondria;GO:0007275//multicellular organismal development;GO:0008340//determination of adult lifespan;GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0007569//cell aging;GO:0010165//response to X-ray;GO:0002360//T cell lineage commitment;GO:0034613//cellular protein localization;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0046677//response to antibiotic;GO:0007265//Ras protein signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth;GO:0048568//embryonic organ development;GO:0009303//rRNA transcription;GO:0043525//positive regulation of neuron apoptotic process;GO:0002931//response to ischemia;GO:0070266//necroptotic process;GO:0007050//cell cycle arrest;GO:0034103//regulation of tissue remodeling;GO:0032461//positive regulation of protein oligomerization;GO:0000733//DNA strand renaturation;GO:0007369//gastrulation;GO:0090343//positive regulation of cell aging;GO:0033077//T cell differentiation in thymus;GO:0031497//chromatin assembly;GO:0007406//negative regulation of neuroblast proliferation;GO:0001756//somitogenesis;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008104//protein localization;GO:0002309//T cell proliferation involved in immune response;GO:0010332//response to gamma radiation;GO:0051402//neuron apoptotic process;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0035264//multicellular organism growth;GO:0097252//oligodendrocyte apoptotic process;GO:0007219//Notch signaling pathway;GO:2000378//negative regulation of reactive oxygen species metabolic process;GO:0006983//ER overload response;GO:0000060//protein import into nucleus, translocation;GO:0030154//cell differentiation;GO:0042981//regulation of apoptotic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0048147//negative regulation of fibroblast proliferation;GO:0090399//replicative senescence;GO:0045892//negative regulation of transcription, DNA-templated",GO:0031625//ubiquitin protein ligase binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0002039//p53 binding;GO:0035035//histone acetyltransferase binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0019903//protein phosphatase binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0051721//protein phosphatase 2A binding;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0003677//DNA binding;GO:0051087//chaperone binding;GO:0030971//receptor tyrosine kinase binding;GO:0047485//protein N-terminus binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0035033//histone deacetylase regulator activity;GO:0008270//zinc ion binding;GO:0003684//damaged DNA binding;GO:0097371//MDM2/MDM4 family protein binding;GO:0005507//copper ion binding;GO:0002020//protease binding,K04451//Colorectal cancer;Epstein-Barr virus infection;Cell cycle;Bladder cancer;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Chronic myeloid leukemia;Apoptosis;Herpes simplex infection;MAPK signaling pathway;Small cell lung cancer;Prostate cancer;Basal cell carcinoma;Huntington's disease;Pancreatic cancer;Pathways in cancer;Thyroid cancer;p53 signaling pathway;Glioma;Measles;Hepatitis C;Melanoma;Neurotrophin signaling pathway;Non-small cell lung cancer;Endometrial cancer;Transcriptional misregulation in cancer;HTLV-I infection
7158,0,1,91,60,146,30,48,0,59,0,94,0,TP53BP1;tumor protein p53 binding protein 1,"GO:0000777//condensed chromosome kinetochore;GO:0005657//replication fork;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000781//chromosome, telomeric region","GO:0000724//double-strand break repair via homologous recombination;GO:0006366//transcription from RNA polymerase II promoter;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006974//cellular response to DNA damage stimulus",GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0002039//p53 binding;GO:0003684//damaged DNA binding;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0042162//telomeric DNA binding,K04574//Amyotrophic lateral sclerosis (ALS);K00907//Gastric acid secretion;Calcium signaling pathway;Focal adhesion;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
7159,0,0,0,23,43,20,0,0,37,0,8,0,TP53BP2;tumor protein p53 binding protein 2,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0009967//positive regulation of signal transduction;GO:0007507//heart development;GO:0010212//response to ionizing radiation;GO:0007165//signal transduction;GO:0007049//cell cycle;GO:0072332//intrinsic apoptotic signaling pathway by p53 class mediator;GO:0045786//negative regulation of cell cycle;GO:0009792//embryo development ending in birth or egg hatching;GO:0007417//central nervous system development,GO:0017124//SH3 domain binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0051059//NF-kappaB binding;GO:0005070//SH3/SH2 adaptor activity,K06270//Long-term potentiation;Focal adhesion;Regulation of actin cytoskeleton;Vascular smooth muscle contraction
716,0,0,0,0,0,0,0,0,29,0,2,0,"C1S;complement component 1, s subcomponent",GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0006958//complement activation, classical pathway;GO:0006508//proteolysis;GO:0045087//innate immune response;GO:0006956//complement activation",GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K01331//Staphylococcus aureus infection;Systemic lupus erythematosus;Complement and coagulation cascades;Pertussis
7161,99,25,0,0,43,10,41,0,90,0,17,0,TP73;tumor protein p73,GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0000785//chromatin;GO:0005829//cytosol,"GO:0007050//cell cycle arrest;GO:0009791//post-embryonic development;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0043524//negative regulation of neuron apoptotic process;GO:0006351//transcription, DNA-templated;GO:0048666//neuron development;GO:0021766//hippocampus development;GO:0001822//kidney development;GO:0033326//cerebrospinal fluid secretion;GO:0043065//positive regulation of apoptotic process;GO:0010165//response to X-ray;GO:0010243//response to organonitrogen compound;GO:0006974//cellular response to DNA damage stimulus;GO:0006298//mismatch repair;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0048546//digestive tract morphogenesis;GO:0001836//release of cytochrome c from mitochondria;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034644//cellular response to UV;GO:0000187//activation of MAPK activity;GO:0010332//response to gamma radiation;GO:0051262//protein tetramerization;GO:1902167//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0043508//negative regulation of JUN kinase activity;GO:0045665//negative regulation of neuron differentiation;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0045793//positive regulation of cell size;GO:0045893//positive regulation of transcription, DNA-templated;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator",GO:0008134//transcription factor binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003684//damaged DNA binding;GO:0002039//p53 binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding,K10148//p53 signaling pathway;Measles;Neurotrophin signaling pathway
7162,4,0,0,8,0,14,0,0,8,1,12,560,TPBG;trophoblast glycoprotein,GO:0005887//integral component of plasma membrane;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface,GO:0007155//cell adhesion,-,K06260//ECM-receptor interaction;Hematopoietic cell lineage;K06839//Axon guidance;K06850//Axon guidance
7163,1,62,6,223,553,23,0,0,31,0,6,0,TPD52;tumor protein D52,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum,GO:0046903//secretion;GO:0009653//anatomical structure morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0030183//B cell differentiation,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
7164,0,0,0,5,1,0,0,0,0,0,0,0,TPD52L1;tumor protein D52-like 1,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0000086//G2/M transition of mitotic cell cycle;GO:0043406//positive regulation of MAP kinase activity;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0046330//positive regulation of JNK cascade;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding;GO:0005515//protein binding,-
7165,0,0,0,0,1,0,0,0,0,0,0,0,TPD52L2;tumor protein D52-like 2,GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0042127//regulation of cell proliferation,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,-
7166,0,0,0,0,0,13,0,0,17,0,0,0,TPH1;tryptophan hydroxylase 1,GO:0043005//neuron projection;GO:0005829//cytosol,GO:0007623//circadian rhythm;GO:0046849//bone remodeling;GO:0034641//cellular nitrogen compound metabolic process;GO:0042427//serotonin biosynthetic process;GO:0060749//mammary gland alveolus development;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0046219//indolalkylamine biosynthetic process;GO:0030279//negative regulation of ossification;GO:0035902//response to immobilization stress;GO:0009072//aromatic amino acid family metabolic process,GO:0004510//tryptophan 5-monooxygenase activity;GO:0005506//iron ion binding;GO:0016597//amino acid binding,K00502//Metabolic pathways;Serotonergic synapse;Tryptophan metabolism
7167,0,79,3,31,106,0,0,0,0,22,6,0,TPI1;triosephosphate isomerase 1,GO:0005634//nucleus;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0019682//glyceraldehyde-3-phosphate metabolic process;GO:0006098//pentose-phosphate shunt;GO:0006094//gluconeogenesis;GO:0007275//multicellular organismal development;GO:0005975//carbohydrate metabolic process;GO:0006096//glycolytic process;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process,GO:0004807//triose-phosphate isomerase activity;GO:0005515//protein binding,K01803//Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism;Inositol phosphate metabolism;Carbon fixation in photosynthetic organisms;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites
7168,0,0,0,11,12,0,1,0,21,0,0,0,TPM1;tropomyosin 1 (alpha),GO:0005862//muscle thin filament tropomyosin;GO:0032059//bleb;GO:0005856//cytoskeleton;GO:0031941//filamentous actin;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0030017//sarcomere;GO:0001725//stress fiber,GO:0045785//positive regulation of cell adhesion;GO:0030049//muscle filament sliding;GO:0051496//positive regulation of stress fiber assembly;GO:0006936//muscle contraction;GO:0006928//cellular component movement;GO:0003065//positive regulation of heart rate by epinephrine;GO:0006937//regulation of muscle contraction;GO:0045214//sarcomere organization;GO:0031529//ruffle organization;GO:0034614//cellular response to reactive oxygen species;GO:0032781//positive regulation of ATPase activity;GO:0001701//in utero embryonic development;GO:0060048//cardiac muscle contraction;GO:0030336//negative regulation of cell migration;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0007010//cytoskeleton organization;GO:0008016//regulation of heart contraction;GO:0042060//wound healing,GO:0008092//cytoskeletal protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0008307//structural constituent of muscle;GO:0003779//actin binding,K09290//Pathways in cancer;Hypertrophic cardiomyopathy (HCM);Thyroid cancer;Cardiac muscle contraction;Dilated cardiomyopathy;K10373//Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);K10375//Cardiac muscle contraction;Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
717,0,0,0,0,0,0,0,1,0,2,3,0,C2;complement component 2,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,"GO:0006508//proteolysis;GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:2000427//positive regulation of apoptotic cell clearance;GO:0006956//complement activation;GO:0045087//innate immune response",GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding,K01335//Complement and coagulation cascades;Staphylococcus aureus infection;K01332//Systemic lupus erythematosus;Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades
7170,2,56,0,32,157,13,0,0,128,0,9,0,TPM3;tropomyosin 3,GO:0005862//muscle thin filament tropomyosin;GO:0005856//cytoskeleton;GO:0001725//stress fiber;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0006936//muscle contraction;GO:0006928//cellular component movement;GO:0030049//muscle filament sliding,GO:0003779//actin binding,K10373//Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;K09290//Dilated cardiomyopathy;Thyroid cancer;Cardiac muscle contraction;Pathways in cancer;Hypertrophic cardiomyopathy (HCM)
7171,0,95,0,41,150,0,0,7,20,0,0,0,TPM4;tropomyosin 4,GO:0005829//cytosol;GO:0031941//filamentous actin;GO:0005925//focal adhesion;GO:0030863//cortical cytoskeleton;GO:0002102//podosome;GO:0001725//stress fiber;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0005862//muscle thin filament tropomyosin,GO:0001649//osteoblast differentiation;GO:0030049//muscle filament sliding;GO:0006928//cellular component movement;GO:0006936//muscle contraction,GO:0005509//calcium ion binding;GO:0003779//actin binding;GO:0008307//structural constituent of muscle,K10375//Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM)
7172,1,0,0,42,59,0,23,2,31,0,0,0,TPMT;thiopurine S-methyltransferase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0033574//response to testosterone;GO:0006139//nucleobase-containing compound metabolic process;GO:0044281//small molecule metabolic process;GO:0032259//methylation;GO:0006805//xenobiotic metabolic process,GO:0008119//thiopurine S-methyltransferase activity,K00569//Drug metabolism - other enzymes
7173,0,10,0,5,0,0,28,27,36,11,12,0,TPO;thyroid peroxidase,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0009986//cell surface;GO:0005615//extracellular space,GO:0006590//thyroid hormone generation;GO:0044281//small molecule metabolic process;GO:0042446//hormone biosynthetic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0035162//embryonic hemopoiesis;GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process,GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0004447//iodide peroxidase activity;GO:0005509//calcium ion binding,K00431//Hematopoietic cell lineage;Cytokine-cytokine receptor interaction;Tyrosine metabolism;Metabolic pathways;Autoimmune thyroid disease;Jak-STAT signaling pathway
7174,0,11,0,15,69,16,49,0,81,0,0,6,TPP2;tripeptidyl peptidase II,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0006508//proteolysis;GO:0000209//protein polyubiquitination;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I,GO:0004252//serine-type endopeptidase activity;GO:0004177//aminopeptidase activity;GO:0004175//endopeptidase activity;GO:0008240//tripeptidyl-peptidase activity,-
7175,0,44,0,72,97,13,37,0,62,2,1,293,"TPR;translocated promoter region, nuclear basket protein",GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0000776//kinetochore;GO:0005868//cytoplasmic dynein complex;GO:0072686//mitotic spindle;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0034399//nuclear periphery;GO:0005634//nucleus;GO:0044615//nuclear pore nuclear basket;GO:0042405//nuclear inclusion body,GO:0035457//cellular response to interferon-alpha;GO:0006405//RNA export from nucleus;GO:0034605//cellular response to heat;GO:0070849//response to epidermal growth factor;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0046832//negative regulation of RNA export from nucleus;GO:0010965//regulation of mitotic sister chromatid separation;GO:0016032//viral process;GO:0006606//protein import into nucleus;GO:0042307//positive regulation of protein import into nucleus;GO:0046827//positive regulation of protein export from nucleus;GO:0010827//regulation of glucose transport;GO:0010793//regulation of mRNA export from nucleus;GO:0043578//nuclear matrix organization;GO:0007094//mitotic spindle assembly checkpoint;GO:0006999//nuclear pore organization;GO:0090316//positive regulation of intracellular protein transport;GO:0006611//protein export from nucleus;GO:0044281//small molecule metabolic process;GO:0031453//positive regulation of heterochromatin assembly;GO:0051292//nuclear pore complex assembly;GO:0000189//MAPK import into nucleus;GO:0055085//transmembrane transport;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0031647//regulation of protein stability;GO:0031990//mRNA export from nucleus in response to heat stress;GO:0015758//glucose transport;GO:0006404//RNA import into nucleus;GO:0007067//mitotic nuclear division;GO:0005975//carbohydrate metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0045947//negative regulation of translational initiation;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0046825//regulation of protein export from nucleus;GO:1901673//regulation of spindle assembly involved in mitosis,GO:0051019//mitogen-activated protein kinase binding;GO:0043495//protein anchor;GO:0003682//chromatin binding;GO:0070840//dynein complex binding;GO:0003729//mRNA binding;GO:0015631//tubulin binding;GO:0005215//transporter activity;GO:0042803//protein homodimerization activity;GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0031072//heat shock protein binding,K09291//Thyroid cancer;RNA transport;Pathways in cancer;MAPK signaling pathway - yeast
7178,0,1421,107,1252,8940,2,28,33,44,0,0,0,"TPT1;tumor protein, translationally-controlled 1",GO:0005771//multivesicular body;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0045298//tubulin complex,GO:2000384//negative regulation of ectoderm development;GO:0019827//stem cell maintenance;GO:1902230//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0043066//negative regulation of apoptotic process;GO:0006816//calcium ion transport;GO:0009615//response to virus;GO:0042981//regulation of apoptotic process;GO:0006874//cellular calcium ion homeostasis,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008134//transcription factor binding;GO:0005509//calcium ion binding,K11447//Transcriptional misregulation in cancer;K04168//Neuroactive ligand-receptor interaction
7179,0,0,29,0,0,22,73,0,52,0,19,0,TPTE;transmembrane phosphatase with tensin homology,GO:0016021//integral component of membrane,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0034220//ion transmembrane transport;GO:0007165//signal transduction,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0005216//ion channel activity;GO:0004725//protein tyrosine phosphatase activity,K01110//Tight junction;Pathways in cancer;Phosphatidylinositol signaling system;Prostate cancer;Small cell lung cancer;Endometrial cancer;Melanoma;Glioma;p53 signaling pathway;Inositol phosphate metabolism;Focal adhesion
718,89,0,30,1,23,0,50,33,18,126,14,0,C3;complement component 3,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0010884//positive regulation of lipid storage;GO:0001970//positive regulation of activation of membrane attack complex;GO:0030449//regulation of complement activation;GO:0045766//positive regulation of angiogenesis;GO:0045087//innate immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045745//positive regulation of G-protein coupled receptor protein signaling pathway;GO:0006631//fatty acid metabolic process;GO:0006958//complement activation, classical pathway;GO:0006957//complement activation, alternative pathway;GO:0006955//immune response;GO:2000427//positive regulation of apoptotic cell clearance;GO:0006956//complement activation;GO:0007165//signal transduction;GO:0006954//inflammatory response;GO:0050776//regulation of immune response;GO:0010828//positive regulation of glucose transport;GO:0001934//positive regulation of protein phosphorylation;GO:0010866//regulation of triglyceride biosynthetic process;GO:0010951//negative regulation of endopeptidase activity;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0001798//positive regulation of type IIa hypersensitivity",GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity;GO:0005515//protein binding;GO:0031715//C5L2 anaphylatoxin chemotactic receptor binding,K03990//Leishmaniasis;Systemic lupus erythematosus;Herpes simplex infection;Staphylococcus aureus infection;Tuberculosis;Legionellosis;Pertussis;Complement and coagulation cascades;Chagas disease (American trypanosomiasis);Phagosome
7180,0,21,30,5,10,0,0,0,0,0,0,0,CRISP2;cysteine-rich secretory protein 2,GO:0005615//extracellular space,GO:0016337//single organismal cell-cell adhesion,-,K02330//Base excision repair;HTLV-I infection
7181,0,0,0,0,0,18,0,0,10,0,0,0,"NR2C1;nuclear receptor subfamily 2, group C, member 1",GO:0005654//nucleoplasm;GO:0016605//PML body,GO:0010467//gene expression;GO:0048386//positive regulation of retinoic acid receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter,GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0004872//receptor activity;GO:0003677//DNA binding;GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding,-
7182,82,48,0,20,62,19,0,64,71,0,52,0,"NR2C2;nuclear receptor subfamily 2, group C, member 2",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0007283//spermatogenesis;GO:0007399//nervous system development;GO:0010467//gene expression;GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0004872//receptor activity;GO:0003713//transcription coactivator activity;GO:0043565//sequence-specific DNA binding,-
7184,1,0,0,29,79,29,1,0,37,111,0,0,"HSP90B1;heat shock protein 90kDa beta (Grp94), member 1",GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0005789//endoplasmic reticulum membrane;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0071682//endocytic vesicle lumen,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0045087//innate immune response;GO:0071318//cellular response to ATP;GO:0044267//cellular protein metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0015031//protein transport;GO:0002224//toll-like receptor signaling pathway;GO:0051208//sequestering of calcium ion;GO:0001666//response to hypoxia;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0031247//actin rod assembly;GO:0006457//protein folding;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0050750//low-density lipoprotein particle receptor binding;GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0046790//virion binding;GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding,K09487//Pathways in cancer;Protein processing in endoplasmic reticulum;Plant-pathogen interaction;NOD-like receptor signaling pathway;Prostate cancer
7185,0,0,0,0,0,7,19,59,0,0,0,232,TRAF1;TNF receptor-associated factor 1,GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0006915//apoptotic process;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:0006461//protein complex assembly,GO:0005164//tumor necrosis factor receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031996//thioesterase binding,K03172//Pathways in cancer;Herpes simplex infection;NF-kappa B signaling pathway;Transcriptional misregulation in cancer;Epstein-Barr virus infection;Small cell lung cancer
7186,0,0,0,0,0,0,38,35,20,0,2,0,TRAF2;TNF receptor-associated factor 2,GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0045121//membrane raft,GO:0002726//positive regulation of T cell cytokine production;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0034351//negative regulation of glial cell apoptotic process;GO:0051865//protein autoubiquitination;GO:0045087//innate immune response;GO:0006461//protein complex assembly;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0050870//positive regulation of T cell activation;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0090073//positive regulation of protein homodimerization activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0051023//regulation of immunoglobulin secretion;GO:0097300//programmed necrotic cell death;GO:0006915//apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0070207//protein homotrimerization;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0032743//positive regulation of interleukin-2 production;GO:0070534//protein K63-linked ubiquitination;GO:0097190//apoptotic signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0051291//protein heterooligomerization;GO:0043623//cellular protein complex assembly;GO:0042981//regulation of apoptotic process;GO:0071732//cellular response to nitric oxide;GO:0007165//signal transduction;GO:0030163//protein catabolic process,GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding;GO:0004871//signal transducer activity;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0019899//enzyme binding;GO:0032403//protein complex binding;GO:0019903//protein phosphatase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046625//sphingolipid binding;GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0008270//zinc ion binding;GO:0031996//thioesterase binding;GO:0005174//CD40 receptor binding,K03173//RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;MAPK signaling pathway;Herpes simplex infection;Apoptosis;Osteoclast differentiation;Protein processing in endoplasmic reticulum;Adipocytokine signaling pathway;Hepatitis C;Small cell lung cancer;Pathways in cancer;NF-kappa B signaling pathway
7187,72,0,0,0,32,0,43,0,70,49,7,7,TRAF3;TNF receptor-associated factor 3,GO:0005768//endosome;GO:0009898//cytoplasmic side of plasma membrane;GO:0035631//CD40 receptor complex;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0007165//signal transduction;GO:0008063//Toll signaling pathway;GO:0030162//regulation of proteolysis;GO:0006915//apoptotic process;GO:0001817//regulation of cytokine production;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0050688//regulation of defense response to virus;GO:0002224//toll-like receptor signaling pathway;GO:0032648//regulation of interferon-beta production;GO:0034142//toll-like receptor 4 signaling pathway;GO:0016567//protein ubiquitination,GO:0004871//signal transducer activity;GO:0016874//ligase activity;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding,K03174//Pathways in cancer;NF-kappa B signaling pathway;Toll-like receptor signaling pathway;Small cell lung cancer;Herpes simplex infection;Hepatitis C;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection
7188,0,0,0,0,0,0,36,0,36,0,2,0,TRAF5;TNF receptor-associated factor 5,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane,GO:0042981//regulation of apoptotic process;GO:0008284//positive regulation of cell proliferation;GO:0007165//signal transduction;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination,GO:0004871//signal transducer activity;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0031996//thioesterase binding,K09849//NF-kappa B signaling pathway;Herpes simplex infection;Pathways in cancer;Epstein-Barr virus infection;Small cell lung cancer
7189,7,0,0,0,12,1,0,52,23,0,0,0,"TRAF6;TNF receptor-associated factor 6, E3 ubiquitin protein ligase",GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0005811//lipid particle;GO:0010008//endosome membrane;GO:0035631//CD40 receptor complex;GO:0009898//cytoplasmic side of plasma membrane;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion,"GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034162//toll-like receptor 9 signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0032743//positive regulation of interleukin-2 production;GO:0048661//positive regulation of smooth muscle cell proliferation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0031398//positive regulation of protein ubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0001843//neural tube closure;GO:0000209//protein polyubiquitination;GO:0045410//positive regulation of interleukin-6 biosynthetic process;GO:0032147//activation of protein kinase activity;GO:0043066//negative regulation of apoptotic process;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0045087//innate immune response;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006461//protein complex assembly;GO:0042088//T-helper 1 type immune response;GO:0051865//protein autoubiquitination;GO:0048468//cell development;GO:0051023//regulation of immunoglobulin secretion;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045084//positive regulation of interleukin-12 biosynthetic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0030316//osteoclast differentiation;GO:0043507//positive regulation of JUN kinase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0070534//protein K63-linked ubiquitination;GO:0031293//membrane protein intracellular domain proteolysis;GO:0045453//bone resorption;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070555//response to interleukin-1;GO:0070498//interleukin-1-mediated signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0045672//positive regulation of osteoclast differentiation;GO:0000187//activation of MAPK activity;GO:0002726//positive regulation of T cell cytokine production;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0001503//ossification;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043011//myeloid dendritic cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway",GO:0042826//histone deacetylase binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0016874//ligase activity;GO:0004871//signal transducer activity;GO:0047485//protein N-terminus binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0031624//ubiquitin conjugating enzyme binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0043422//protein kinase B binding;GO:0031996//thioesterase binding,K03175//MAPK signaling pathway;Herpes simplex infection;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Pathways in cancer;Endocytosis;NF-kappa B signaling pathway;Pertussis;Tuberculosis;Toll-like receptor signaling pathway;Small cell lung cancer;Leishmaniasis;Toxoplasmosis;Osteoclast differentiation;Neurotrophin signaling pathway;Hepatitis C;Measles;Chagas disease (American trypanosomiasis);Ubiquitin mediated proteolysis;NOD-like receptor signaling pathway
719,0,0,0,0,0,0,6,0,0,0,4,5,C3AR1;complement component 3a receptor 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0008152//metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0010759//positive regulation of macrophage chemotaxis;GO:0002430//complement receptor mediated signaling pathway;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0006935//chemotaxis;GO:0008015//blood circulation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045766//positive regulation of angiogenesis;GO:0006954//inflammatory response;GO:0090023//positive regulation of neutrophil chemotaxis,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0004943//C3a anaphylatoxin receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004876//complement component C3a receptor activity,K04009//Staphylococcus aureus infection;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
7190,0,0,0,0,0,0,0,0,13,0,0,0,"HSP90B2P;heat shock protein 90kDa beta (Grp94), member 2, pseudogene",-,GO:0006457//protein folding;GO:0006950//response to stress,GO:0005524//ATP binding;GO:0051082//unfolded protein binding,K09487//Pathways in cancer;Protein processing in endoplasmic reticulum;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction
72,0,0,0,0,0,0,0,0,21,0,0,0,"ACTG2;actin, gamma 2, smooth muscle, enteric",GO:0071944//cell periphery;GO:0005856//cytoskeleton;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0006936//muscle contraction,GO:0005524//ATP binding,K12315//Vascular smooth muscle contraction
7200,12,0,1,0,0,31,0,0,11,26,0,0,TRH;thyrotropin-releasing hormone,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0030141//secretory granule;GO:0005634//nucleus,GO:0007628//adult walking behavior;GO:0045471//response to ethanol;GO:0042755//eating behavior;GO:0014050//negative regulation of glutamate secretion;GO:0009409//response to cold;GO:0001666//response to hypoxia;GO:0051412//response to corticosterone;GO:0009755//hormone-mediated signaling pathway;GO:0014054//positive regulation of gamma-aminobutyric acid secretion;GO:0007165//signal transduction;GO:2000252//negative regulation of feeding behavior;GO:0007267//cell-cell signaling;GO:0009749//response to glucose;GO:0032024//positive regulation of insulin secretion,GO:0005184//neuropeptide hormone activity,-
7201,0,0,0,0,0,0,40,0,27,0,0,0,TRHR;thyrotropin-releasing hormone receptor,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004997//thyrotropin-releasing hormone receptor activity,K04282//Neuroactive ligand-receptor interaction;Calcium signaling pathway
7203,33,26,1,27,82,1,38,0,85,0,12,0,"CCT3;chaperonin containing TCP1, subunit 3 (gamma)",GO:0002199//zona pellucida receptor complex;GO:0005829//cytosol;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005832//chaperonin-containing T-complex;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0044297//cell body,GO:0044267//cellular protein metabolic process;GO:0007339//binding of sperm to zona pellucida;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding,GO:0005524//ATP binding;GO:0051082//unfolded protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
7204,2,65,0,28,117,30,17,0,48,257,6,0,TRIO;trio Rho guanine nucleotide exchange factor,GO:0005829//cytosol,GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0007411//axon guidance;GO:0007185//transmembrane receptor protein tyrosine phosphatase signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005524//ATP binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0019899//enzyme binding;GO:0004674//protein serine/threonine kinase activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
7205,0,0,0,0,17,15,71,0,32,219,0,0,TRIP6;thyroid hormone receptor interactor 6,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0045323//interleukin-1 receptor complex;GO:0005886//plasma membrane;GO:0005925//focal adhesion,"GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0006351//transcription, DNA-templated;GO:0048041//focal adhesion assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0030335//positive regulation of cell migration",GO:0019900//kinase binding;GO:0046966//thyroid hormone receptor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0005149//interleukin-1 receptor binding,K12792//NOD-like receptor signaling pathway
7216,0,30,0,0,1,0,0,1,12,0,18,0,TRO;trophinin,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030308//negative regulation of cell growth;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007566//embryo implantation,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
722,0,0,0,0,0,15,16,0,11,0,0,0,"C4BPA;complement component 4 binding protein, alpha",GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0044216//other organism cell,"GO:0045732//positive regulation of protein catabolic process;GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0045959//negative regulation of complement activation, classical pathway;GO:0045087//innate immune response;GO:1903027//regulation of opsonization",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K04002//Complement and coagulation cascades;Pertussis
7220,0,0,0,0,0,4,25,0,88,0,0,0,"TRPC1;transient receptor potential cation channel, subfamily C, member 1",GO:0005886//plasma membrane;GO:0043034//costamere;GO:0045121//membrane raft;GO:0016323//basolateral plasma membrane;GO:0030017//sarcomere;GO:0005887//integral component of plasma membrane;GO:0043235//receptor complex,GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0055085//transmembrane transport;GO:0051480//cytosolic calcium ion homeostasis;GO:0051592//response to calcium ion;GO:0070588//calcium ion transmembrane transport;GO:0007411//axon guidance;GO:0006816//calcium ion transport;GO:0034220//ion transmembrane transport;GO:0046541//saliva secretion,"GO:0015279//store-operated calcium channel activity;GO:0044325//ion channel binding;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0005261//cation channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding",K04964//Serotonergic synapse;Pancreatic secretion;Glutamatergic synapse
7221,23,0,0,0,0,5,1,0,13,0,0,0,"TRPC2;transient receptor potential cation channel, subfamily C, member 2, pseudogene",-,-,-,-
7222,0,0,0,0,0,8,5,0,21,0,13,0,"TRPC3;transient receptor potential cation channel, subfamily C, member 3",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0051592//response to calcium ion;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0007411//axon guidance;GO:0006816//calcium ion transport;GO:0007602//phototransduction;GO:0007596//blood coagulation;GO:0034220//ion transmembrane transport;GO:0030168//platelet activation;GO:0033198//response to ATP;GO:0010524//positive regulation of calcium ion transport into cytosol,"GO:0015279//store-operated calcium channel activity;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0070679//inositol 1,4,5 trisphosphate binding",-
7223,72,0,0,0,0,35,0,0,33,0,0,0,"TRPC4;transient receptor potential cation channel, subfamily C, member 4",GO:0034704//calcium channel complex;GO:0005911//cell-cell junction;GO:0005901//caveola;GO:0030863//cortical cytoskeleton;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016323//basolateral plasma membrane,GO:0070509//calcium ion import;GO:0048709//oligodendrocyte differentiation;GO:0034220//ion transmembrane transport;GO:0014051//gamma-aminobutyric acid secretion;GO:0007411//axon guidance;GO:0006816//calcium ion transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport,"GO:0015279//store-operated calcium channel activity;GO:0045296//cadherin binding;GO:0005515//protein binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0008013//beta-catenin binding",-
7224,0,0,0,0,0,19,0,0,76,0,0,0,"TRPC5;transient receptor potential cation channel, subfamily C, member 5",GO:0034704//calcium channel complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0007399//nervous system development;GO:0006816//calcium ion transport;GO:0007411//axon guidance,"GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding",-
7225,0,0,0,0,0,0,84,0,23,0,0,0,"TRPC6;transient receptor potential cation channel, subfamily C, member 6",GO:0036057//slit diaphragm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007411//axon guidance;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006812//cation transport;GO:0070301//cellular response to hydrogen peroxide;GO:0051928//positive regulation of calcium ion transport;GO:0007596//blood coagulation;GO:0032414//positive regulation of ion transmembrane transporter activity;GO:0030168//platelet activation;GO:0071456//cellular response to hypoxia;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007568//aging,"GO:0005515//protein binding;GO:0015279//store-operated calcium channel activity;GO:0070679//inositol 1,4,5 trisphosphate binding",-
7226,152,0,0,0,0,15,6,0,48,5,27,0,"TRPM2;transient receptor potential cation channel, subfamily M, member 2",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0071421//manganese ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0008152//metabolic process;GO:0035725//sodium ion transmembrane transport;GO:0033194//response to hydroperoxide;GO:0006816//calcium ion transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005272//sodium channel activity;GO:0005384//manganese ion transmembrane transporter activity;GO:0047631//ADP-ribose diphosphatase activity;GO:0005262//calcium channel activity,-
7227,0,1,0,23,67,17,51,0,61,0,6,0,TRPS1;trichorhinophalangeal syndrome I,GO:0005634//nucleus,GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0032330//regulation of chondrocyte differentiation;GO:0006607//NLS-bearing protein import into nucleus;GO:0031063//regulation of histone deacetylation;GO:0001501//skeletal system development;GO:0006366//transcription from RNA polymerase II promoter;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0002062//chondrocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
723779,0,0,0,0,0,9,0,0,0,0,0,0,MIR651;microRNA 651,-,-,-,-
723972,0,0,0,0,18,0,0,0,0,0,0,0,"ANP32AP1;acidic (leucine-rich) nuclear phosphoprotein 32 family, member A pseudogene 1",-,-,-,K11092//Spliceosome
724030,22,0,0,0,0,0,0,0,0,0,0,0,MIR660;microRNA 660,-,-,-,-
724032,0,1,0,0,0,0,0,0,0,0,0,0,MIR662;microRNA 662,-,-,-,-
7247,0,0,0,0,35,0,0,0,43,83,0,0,TSN;translin,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006310//DNA recombination;GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0004519//endonuclease activity;GO:0032403//protein complex binding,-
7248,0,16,1,36,4,22,0,179,117,0,18,0,TSC1;tuberous sclerosis 1,GO:0016020//membrane;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0043234//protein complex;GO:0030027//lamellipodium;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0033596//TSC1-TSC2 complex;GO:0005884//actin filament,GO:0001822//kidney development;GO:0021766//hippocampus development;GO:0032868//response to insulin;GO:0051492//regulation of stress fiber assembly;GO:0051726//regulation of cell cycle;GO:0006417//regulation of translation;GO:0050821//protein stabilization;GO:0050808//synapse organization;GO:0008285//negative regulation of cell proliferation;GO:0001952//regulation of cell-matrix adhesion;GO:0051894//positive regulation of focal adhesion assembly;GO:0032862//activation of Rho GTPase activity;GO:0006813//potassium ion transport;GO:0043666//regulation of phosphoprotein phosphatase activity;GO:0045859//regulation of protein kinase activity;GO:0017148//negative regulation of translation;GO:0001843//neural tube closure;GO:0045792//negative regulation of cell size;GO:0007050//cell cycle arrest;GO:0030030//cell projection organization;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0055007//cardiac muscle cell differentiation;GO:0042552//myelination;GO:0006407//rRNA export from nucleus;GO:0032007//negative regulation of TOR signaling;GO:0021987//cerebral cortex development;GO:0007160//cell-matrix adhesion,GO:0032794//GTPase activating protein binding;GO:0030695//GTPase regulator activity;GO:0051087//chaperone binding;GO:0047485//protein N-terminus binding;GO:0005515//protein binding,K07206//Insulin signaling pathway;mTOR signaling pathway
7249,0,27,1,0,4,29,0,0,64,0,4,0,TSC2;tuberous sclerosis 2,GO:0005829//cytosol;GO:0033596//TSC1-TSC2 complex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005901//caveola;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0030425//dendrite;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0030426//growth cone,GO:0045087//innate immune response;GO:0043491//protein kinase B signaling;GO:0050918//positive chemotaxis;GO:0007507//heart development;GO:0030100//regulation of endocytosis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051726//regulation of cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0006606//protein import into nucleus;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0051898//negative regulation of protein kinase B signaling;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001843//neural tube closure;GO:0007050//cell cycle arrest;GO:0006897//endocytosis;GO:0008286//insulin receptor signaling pathway;GO:0051260//protein homooligomerization;GO:0016192//vesicle-mediated transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006953//acute-phase response;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0008104//protein localization;GO:0030178//negative regulation of Wnt signaling pathway;GO:0045792//negative regulation of cell size;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030030//cell projection organization;GO:0032007//negative regulation of TOR signaling;GO:0043407//negative regulation of MAP kinase activity;GO:0032320//positive regulation of Ras GTPase activity;GO:0001666//response to hypoxia;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0051291//protein heterooligomerization;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0046626//regulation of insulin receptor signaling pathway,GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0071889//14-3-3 protein binding;GO:0005096//GTPase activator activity,K07207//mTOR signaling pathway;Insulin signaling pathway;p53 signaling pathway
725,0,0,0,0,0,0,0,0,1,0,0,0,"C4BPB;complement component 4 binding protein, beta",GO:0005576//extracellular region;GO:0044216//other organism cell;GO:0005886//plasma membrane;GO:0005615//extracellular space,"GO:0030449//regulation of complement activation;GO:0006958//complement activation, classical pathway;GO:0045732//positive regulation of protein catabolic process;GO:1903027//regulation of opsonization;GO:0045087//innate immune response;GO:0045959//negative regulation of complement activation, classical pathway;GO:0007596//blood coagulation",GO:0005515//protein binding,K04003//Pertussis;Complement and coagulation cascades
7251,0,11,0,4,99,0,0,59,18,0,0,0,TSG101;tumor susceptibility 101,GO:0005730//nucleolus;GO:0005771//multivesicular body;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0005770//late endosome;GO:0010008//endosome membrane;GO:0005737//cytoplasm,"GO:0019082//viral protein processing;GO:0015031//protein transport;GO:0008285//negative regulation of cell proliferation;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0006464//cellular protein modification process;GO:0051301//cell division;GO:0001558//regulation of cell growth;GO:0019058//viral life cycle;GO:0046755//viral budding;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030216//keratinocyte differentiation;GO:0075733//intracellular transport of virus;GO:0016197//endosomal transport;GO:0019068//virion assembly;GO:0061024//membrane organization;GO:0016032//viral process;GO:0007050//cell cycle arrest",GO:0043130//ubiquitin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042803//protein homodimerization activity;GO:0048306//calcium-dependent protein binding;GO:0003677//DNA binding,K12183//Endocytosis
7252,0,0,0,0,0,21,0,0,5,0,0,0,"TSHB;thyroid stimulating hormone, beta",GO:0005576//extracellular region,GO:0033189//response to vitamin A;GO:0007267//cell-cell signaling;GO:0016486//peptide hormone processing;GO:0007186//G-protein coupled receptor signaling pathway;GO:0043627//response to estrogen;GO:0044267//cellular protein metabolic process;GO:0051592//response to calcium ion;GO:0009653//anatomical structure morphogenesis,GO:0005179//hormone activity,K05251//Autoimmune thyroid disease;Neuroactive ligand-receptor interaction
7253,0,0,0,0,0,0,0,0,21,0,0,0,TSHR;thyroid stimulating hormone receptor,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030183//B cell differentiation;GO:0040018//positive regulation of multicellular organism growth;GO:0008344//adult locomotory behavior;GO:0008284//positive regulation of cell proliferation;GO:0038194//thyroid-stimulating hormone signaling pathway;GO:0007267//cell-cell signaling;GO:0040012//regulation of locomotion",GO:0005515//protein binding;GO:0004996//thyroid-stimulating hormone receptor activity,K04249//Neuroactive ligand-receptor interaction;Autoimmune thyroid disease
7257,0,36,0,0,123,0,0,0,47,0,5,0,TSNAX;translin-associated factor X,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005794//Golgi apparatus,GO:0030154//cell differentiation;GO:0015031//protein transport;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,GO:0008565//protein transporter activity;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption
7259,0,160,4,209,361,13,15,0,4,1,0,0,TSPYL1;TSPY-like 1,GO:0005730//nucleolus,GO:0006334//nucleosome assembly,GO:0019899//enzyme binding,-
726,87,0,0,13,3,41,19,0,64,0,1,274,CAPN5;calpain 5,GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity,-
7260,0,0,0,0,13,0,0,0,0,0,0,0,TSSC1;tumor suppressing subtransferable candidate 1,-,-,-,K13341//Peroxisome
7262,0,0,0,0,0,3,0,0,0,0,0,217,"PHLDA2;pleckstrin homology-like domain, family A, member 2",GO:0005737//cytoplasm;GO:0016020//membrane,GO:0009887//organ morphogenesis;GO:0030334//regulation of cell migration;GO:0001890//placenta development;GO:0045995//regulation of embryonic development;GO:0070873//regulation of glycogen metabolic process;GO:0010468//regulation of gene expression;GO:0006915//apoptotic process,-,-
7263,0,31,8,0,0,0,0,0,0,0,5,0,TST;thiosulfate sulfurtransferase (rhodanese),GO:0005759//mitochondrial matrix;GO:0005615//extracellular space;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,"GO:0000096//sulfur amino acid metabolic process;GO:0035928//rRNA import into mitochondrion;GO:0034641//cellular nitrogen compound metabolic process;GO:0030855//epithelial cell differentiation;GO:0070221//sulfide oxidation, using sulfide:quinone oxidoreductase;GO:0044281//small molecule metabolic process;GO:0009440//cyanate catabolic process;GO:0000098//sulfur amino acid catabolic process",GO:0008097//5S rRNA binding;GO:0004792//thiosulfate sulfurtransferase activity,K01011//Metabolic pathways;Sulfur relay system;Cysteine and methionine metabolism
7264,0,0,0,4,28,0,0,0,42,56,0,0,TSTA3;tissue specific transplantation antigen P35B,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0019835//cytolysis;GO:0055114//oxidation-reduction process;GO:0007159//leukocyte cell-cell adhesion;GO:0042351//'de novo' GDP-L-fucose biosynthetic process;GO:0019673//GDP-mannose metabolic process,GO:0050577//GDP-L-fucose synthase activity;GO:0050662//coenzyme binding;GO:0016853//isomerase activity;GO:0042356//GDP-4-dehydro-D-rhamnose reductase activity;GO:0009055//electron carrier activity,K02377//Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism
7265,0,26,22,0,1,0,0,0,10,0,0,0,TTC1;tetratricopeptide repeat domain 1,GO:0005778//peroxisomal membrane,GO:0006457//protein folding,GO:0005515//protein binding;GO:0051082//unfolded protein binding,-
7266,59,0,0,66,84,15,19,78,37,0,83,574,"DNAJC7;DnaJ (Hsp40) homolog, subfamily C, member 7",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus,GO:0070389//chaperone cofactor-dependent protein refolding;GO:0006457//protein folding,GO:0031072//heat shock protein binding;GO:0005515//protein binding,-
7267,0,273,5,208,835,14,0,0,113,144,12,309,TTC3;tetratricopeptide repeat domain 3,GO:0005634//nucleus;GO:0005773//vacuole;GO:0005739//mitochondrion;GO:0005730//nucleolus,GO:0045665//negative regulation of neuron differentiation;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010771//negative regulation of cell morphogenesis involved in differentiation;GO:0070936//protein K48-linked ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
7268,0,0,0,0,0,0,0,0,12,0,1,0,TTC4;tetratricopeptide repeat domain 4,-,-,-,-
727,0,0,33,0,4,1,15,0,21,0,31,1,C5;complement component 5,GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005579//membrane attack complex,"GO:0033602//negative regulation of dopamine secretion;GO:0006954//inflammatory response;GO:0090197//positive regulation of chemokine secretion;GO:0002523//leukocyte migration involved in inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0010951//negative regulation of endopeptidase activity;GO:0010575//positive regulation vascular endothelial growth factor production;GO:0006935//chemotaxis;GO:0010700//negative regulation of norepinephrine secretion;GO:0006950//response to stress;GO:0045766//positive regulation of angiogenesis;GO:0006874//cellular calcium ion homeostasis;GO:0045087//innate immune response;GO:0042593//glucose homeostasis;GO:0001701//in utero embryonic development;GO:0060326//cell chemotaxis;GO:0030449//regulation of complement activation;GO:0010760//negative regulation of macrophage chemotaxis;GO:0000187//activation of MAPK activity;GO:0050921//positive regulation of chemotaxis;GO:0019835//cytolysis;GO:0006956//complement activation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway",GO:0005515//protein binding;GO:0005102//receptor binding;GO:0004866//endopeptidase inhibitor activity;GO:0031714//C5a anaphylatoxin chemotactic receptor binding;GO:0008009//chemokine activity,K03994//Systemic lupus erythematosus;Prion diseases;Herpes simplex infection;Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades
7270,0,0,1,14,13,0,6,0,13,1,5,0,"TTF1;transcription termination factor, RNA polymerase I",GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0006353//DNA-templated transcription, termination;GO:0006338//chromatin remodeling;GO:0006355//regulation of transcription, DNA-templated;GO:0008156//negative regulation of DNA replication;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0006360//transcription from RNA polymerase I promoter",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
7272,0,0,26,17,0,18,0,0,44,89,7,0,TTK;TTK protein kinase,GO:0016020//membrane;GO:0005819//spindle,GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007052//mitotic spindle organization;GO:0051304//chromosome separation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007051//spindle organization;GO:0008284//positive regulation of cell proliferation;GO:0007094//mitotic spindle assembly checkpoint,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K08866//Cell cycle;Cell cycle - yeast
7273,336,420,726,464,569,208,440,161,1088,147,508,702,TTN;titin,GO:0031430//M band;GO:0005634//nucleus;GO:0031674//I band;GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005865//striated muscle thin filament;GO:0030018//Z disc;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005576//extracellular region,GO:0006936//muscle contraction;GO:0003300//cardiac muscle hypertrophy;GO:0051592//response to calcium ion;GO:0002576//platelet degranulation;GO:0006468//protein phosphorylation;GO:0007596//blood coagulation;GO:0055008//cardiac muscle tissue morphogenesis;GO:0045214//sarcomere organization;GO:1901897//regulation of relaxation of cardiac muscle;GO:0030168//platelet activation;GO:0007512//adult heart development;GO:0045859//regulation of protein kinase activity;GO:0030240//skeletal muscle thin filament assembly;GO:0050790//regulation of catalytic activity;GO:0048769//sarcomerogenesis;GO:0007076//mitotic chromosome condensation;GO:0006941//striated muscle contraction;GO:0030049//muscle filament sliding;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0035995//detection of muscle stretch;GO:0043056//forward locomotion;GO:0001756//somitogenesis;GO:0048739//cardiac muscle fiber development;GO:0055003//cardiac myofibril assembly;GO:0001701//in utero embryonic development;GO:0060048//cardiac muscle contraction,GO:0051015//actin filament binding;GO:0005516//calmodulin binding;GO:0004674//protein serine/threonine kinase activity;GO:0043621//protein self-association;GO:0005509//calcium ion binding;GO:0031433//telethonin binding;GO:0030506//ankyrin binding;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0008307//structural constituent of muscle;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0042805//actinin binding;GO:0097493//structural molecule activity conferring elasticity;GO:0005515//protein binding;GO:0002020//protease binding;GO:0051371//muscle alpha-actinin binding,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
7274,0,0,0,0,0,0,0,0,45,0,9,0,TTPA;tocopherol (alpha) transfer protein,GO:0005829//cytosol;GO:0005770//late endosome,GO:0060548//negative regulation of cell death;GO:0007584//response to nutrient;GO:0006810//transport;GO:0090212//negative regulation of establishment of blood-brain barrier;GO:0051452//intracellular pH reduction;GO:0046909//intermembrane transport;GO:0001892//embryonic placenta development;GO:0051180//vitamin transport;GO:0009636//response to toxic substance;GO:0009268//response to pH;GO:0006629//lipid metabolic process;GO:0042360//vitamin E metabolic process,"GO:0008431//vitamin E binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005215//transporter activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",-
7275,206,49,8,0,21,10,24,0,86,54,5,1,TUB;tubby bipartite transcription factor,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0044259//multicellular organismal macromolecule metabolic process;GO:0009584//detection of visible light;GO:0007602//phototransduction;GO:0009725//response to hormone;GO:0050766//positive regulation of phagocytosis;GO:0006909//phagocytosis;GO:0007605//sensory perception of sound;GO:0060041//retina development in camera-type eye,GO:0032403//protein complex binding;GO:0008020//G-protein coupled photoreceptor activity,-
7276,0,0,0,0,0,0,20,0,21,0,0,0,TTR;transthyretin,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0005737//cytoplasm,"GO:0001523//retinoid metabolic process;GO:0006810//transport;GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light;GO:0030198//extracellular matrix organization",GO:0046982//protein heterodimerization activity;GO:0005179//hormone activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0042562//hormone binding,K07127//Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments
727684,0,0,0,0,0,0,0,0,9,0,0,0,C1orf195;chromosome 1 open reading frame 195,-,-,-,-
7277,0,1,1,3,52,0,0,1,0,0,73,0,"TUBA4A;tubulin, alpha 4a",GO:0005874//microtubule;GO:0005829//cytosol;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0007596//blood coagulation;GO:0051258//protein polymerization;GO:0006457//protein folding;GO:0006184//GTP catabolic process;GO:0007017//microtubule-based process;GO:0044267//cellular protein metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0002576//platelet degranulation;GO:0051084//'de novo' posttranslational protein folding;GO:0030168//platelet activation,GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07374//Pathogenic Escherichia coli infection;Gap junction;Phagosome
727758,0,0,0,0,19,0,0,71,12,0,0,0,"ROCK1P1;Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1",-,-,-,K04514//TGF-beta signaling pathway;Shigellosis;Leukocyte transendothelial migration;Salmonella infection;Axon guidance;Chemokine signaling pathway;Focal adhesion;Pathogenic Escherichia coli infection;Wnt signaling pathway;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
727764,1,0,0,0,1,8,9,62,79,4,2,0,MAFIP;MAFF interacting protein (pseudogene),GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,K04688//ErbB signaling pathway;Fc gamma R-mediated phagocytosis;TGF-beta signaling pathway;Acute myeloid leukemia;Insulin signaling pathway;mTOR signaling pathway
7278,0,0,0,0,0,0,0,0,0,18,0,0,"TUBA3C;tubulin, alpha 3c",-,-,-,K07374//Phagosome;Gap junction;Pathogenic Escherichia coli infection
727800,0,0,0,0,0,0,21,0,0,0,0,0,RNF208;ring finger protein 208,-,GO:0051865//protein autoubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity,-
727830,0,0,0,0,0,0,0,50,0,0,0,0,"SPATA31A3;SPATA31 subfamily A, member 3",GO:0016021//integral component of membrane,GO:0030154//cell differentiation;GO:0007283//spermatogenesis,-,-
727832,9,0,0,0,0,17,0,0,36,8,3,0,GOLGA6L6;golgin A6 family-like 6,-,-,-,K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
727897,159,0,0,0,0,65,42,101,168,0,40,0,"MUC5B;mucin 5B, oligomeric mucus/gel-forming",GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen;GO:0005615//extracellular space,GO:0010193//response to ozone;GO:0044267//cellular protein metabolic process;GO:0030855//epithelial cell differentiation;GO:0010477//response to sulfur dioxide;GO:0071300//cellular response to retinoic acid;GO:0032496//response to lipopolysaccharide;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0071385//cellular response to glucocorticoid stimulus;GO:0033189//response to vitamin A;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0005515//protein binding,K13908//Salivary secretion
727910,0,0,0,0,3,0,0,40,14,0,10,139,TLCD2;TLC domain containing 2,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer
727924,0,0,0,0,0,0,49,0,0,0,0,0,LOC727924;uncharacterized LOC727924,-,-,-,K04257//Olfactory transduction
727936,0,0,0,0,0,0,26,0,50,0,0,0,GXYLT2;glucoside xylosyltransferase 2,GO:0016021//integral component of membrane,GO:0016266//O-glycan processing,GO:0035252//UDP-xylosyltransferase activity,K13676//Other types of O-glycan biosynthesis
727956,0,0,0,0,1,8,0,0,1,0,2,0,"SDHAP2;succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2",-,-,-,K00234//Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways;Citrate cycle (TCA cycle);Biosynthesis of secondary metabolites
727957,58,0,35,0,0,42,6,1,0,3,1,0,MROH1;maestro heat-like repeat family member 1,-,-,-,-
7280,0,0,0,0,6,0,0,0,8,0,0,0,"TUBB2A;tubulin, beta 2A class IIa",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005634//nucleus;GO:0005874//microtubule,GO:0007017//microtubule-based process;GO:0044267//cellular protein metabolic process;GO:0006184//GTP catabolic process;GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0051258//protein polymerization,GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07375//Gap junction;Phagosome;Pathogenic Escherichia coli infection
728024,0,0,0,0,0,15,0,0,0,0,0,0,LOC728024;chromosome X open reading frame 56 pseudogene,-,-,-,-
728039,0,0,0,0,0,0,0,0,42,0,14,0,"SSR4P1;signal sequence receptor, delta pseudogene 1",-,-,-,K04571//Protein processing in endoplasmic reticulum
728047,0,0,0,0,0,32,1,0,2,22,1,0,"GOLGA8O;golgin A8 family, member O",GO:0005794//Golgi apparatus,-,GO:0005515//protein binding,K12478//Tuberculosis;Endocytosis;Phagosome
728116,0,36,0,0,0,0,39,0,4,0,14,0,ZBTB8B;zinc finger and BTB domain containing 8B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
728118,2,0,0,0,0,2,28,0,1,51,0,0,NUTM2A;NUT family member 2A,-,-,-,-
728130,0,1,0,0,0,31,0,19,0,8,0,0,NUTM2D;NUT family member 2D,-,-,-,-
728215,0,0,0,0,8,0,40,1,34,0,0,313,"FAM155A;family with sequence similarity 155, member A",GO:0016021//integral component of membrane,-,-,-
728224,0,0,0,0,0,1,0,0,11,0,0,0,KRTAP4-8;keratin associated protein 4-8,GO:0045095//keratin filament,GO:0007568//aging;GO:0042633//hair cycle,-,-
728229,0,0,0,0,0,0,0,0,0,0,11,0,TMEM191B;transmembrane protein 191B,GO:0016021//integral component of membrane,-,-,-
728233,0,0,0,0,0,23,1,0,0,1,0,311,"PI4KAP1;phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1",-,GO:0046854//phosphatidylinositol phosphorylation;GO:0048015//phosphatidylinositol-mediated signaling,-,K00888//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
728255,0,0,0,0,0,14,0,0,0,0,0,0,KRTAP1-4;keratin associated protein 1-4,GO:0045095//keratin filament,-,-,-
728262,0,0,0,0,0,0,30,0,32,0,0,0,"FAM157A;family with sequence similarity 157, member A",-,-,-,-
728276,0,4,0,10,0,0,0,0,9,0,0,0,"CLEC19A;C-type lectin domain family 19, member A",GO:0005576//extracellular region,-,GO:0030246//carbohydrate binding,-
728294,0,0,0,0,0,0,1,0,5,7,0,0,D2HGDH;D-2-hydroxyglutarate dehydrogenase,GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process;GO:0032025//response to cobalt ion;GO:0051592//response to calcium ion;GO:0044267//cellular protein metabolic process;GO:0010042//response to manganese ion;GO:0010043//response to zinc ion;GO:0006103//2-oxoglutarate metabolic process;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0032026//response to magnesium ion,GO:0008762//UDP-N-acetylmuramate dehydrogenase activity;GO:0051990//(R)-2-hydroxyglutarate dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding,K00102//Pyruvate metabolism
7283,0,23,0,13,44,22,30,45,25,1,1,0,"TUBG1;tubulin, gamma 1",GO:0000242//pericentriolar material;GO:0005814//centriole;GO:0005829//cytosol;GO:0000794//condensed nuclear chromosome;GO:0005827//polar microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0031513//nonmotile primary cilium;GO:0031252//cell leading edge;GO:0005881//cytoplasmic microtubule;GO:0000930//gamma-tubulin complex;GO:0036064//ciliary basal body,GO:0000086//G2/M transition of mitotic cell cycle;GO:0031122//cytoplasmic microtubule organization;GO:0000278//mitotic cell cycle;GO:0000226//microtubule cytoskeleton organization;GO:0007020//microtubule nucleation;GO:0000212//meiotic spindle organization;GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005200//structural constituent of cytoskeleton;GO:0005515//protein binding,-
728310,0,16,0,1,0,0,0,0,27,0,15,0,"GOLGA6L7P;golgin A6 family-like 7, pseudogene",-,-,-,-
728340,0,0,0,0,0,0,0,0,0,0,0,252,GTF2H2C;GTF2H2 family member C,-,-,-,K03142//Nucleotide excision repair;Basal transcription factors
728377,0,0,1,11,0,0,21,0,42,276,5,0,"ARHGEF34P;Rho guanine nucleotide exchange factor (GEF) 34, pseudogene",-,-,-,K04257//Olfactory transduction
728378,4,31,0,66,21,0,1,0,15,0,37,0,"POTEF;POTE ankyrin domain family, member F",GO:0005938//cell cortex;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0072562//blood microparticle,GO:0001895//retina homeostasis,-,K05692//Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Focal adhesion;Vibrio cholerae infection;Gastric acid secretion;Pathogenic Escherichia coli infection;Salmonella infection;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Viral myocarditis;Phototransduction - fly;Adherens junction
728392,10,0,0,0,0,0,0,0,10,0,0,0,LOC728392;uncharacterized LOC728392,-,-,-,-
728395,0,0,0,0,0,0,0,0,0,1,0,0,"TSPY4;testis specific protein, Y-linked 4",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007506//gonadal mesoderm development;GO:0030154//cell differentiation;GO:0006334//nucleosome assembly;GO:0007283//spermatogenesis,-,-
7284,20,1,0,0,0,10,0,0,5,0,8,0,"TUFM;Tu translation elongation factor, mitochondrial",GO:0070062//extracellular vesicular exosome;GO:0042645//mitochondrial nucleoid;GO:0016020//membrane;GO:0005739//mitochondrion,GO:0006184//GTP catabolic process;GO:0006414//translational elongation,GO:0044822//poly(A) RNA binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding,K02358//Plant-pathogen interaction
728402,0,0,0,0,0,0,18,0,0,0,6,0,TPI1P3;triosephosphate isomerase 1 pseudogene 3,-,-,-,K01803//Inositol phosphate metabolism;Glycolysis / Gluconeogenesis;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism
728407,0,0,0,0,0,19,0,0,0,0,0,0,PARGP1;poly (ADP-ribose) glycohydrolase pseudogene 1,-,-,-,-
728411,123,0,2,0,0,0,43,0,64,1,4,1,"GUSBP1;glucuronidase, beta pseudogene 1",-,-,-,K01195//Porphyrin and chlorophyll metabolism;Glycosaminoglycan degradation;Metabolic pathways;Pentose and glucuronate interconversions;Starch and sucrose metabolism;Drug metabolism - other enzymes;Lysosome
728464,0,0,30,0,0,0,0,61,12,0,0,0,METTL24;methyltransferase like 24,GO:0005576//extracellular region,GO:0032259//methylation,GO:0008168//methyltransferase activity,K12816//Spliceosome
728489,0,0,0,0,23,0,0,103,9,0,0,0,DNLZ;DNL-type zinc finger,GO:0005739//mitochondrion,-,GO:0008270//zinc ion binding,-
728495,0,0,0,0,0,0,0,0,11,0,0,0,"FAM74A3;family with sequence similarity 74, member A3",GO:0016021//integral component of membrane,-,-,K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
728498,0,0,0,5,13,0,8,2,62,0,13,0,"GOLGA8H;golgin A8 family, member H",GO:0005794//Golgi apparatus,-,-,K12478//Tuberculosis;Phagosome;Endocytosis
728524,63,0,0,0,1,0,0,11,4,0,6,0,"SPDYE8P;speedy/RINGO cell cycle regulator family member E8, pseudogene",-,-,-,K08694//Oocyte meiosis;Progesterone-mediated oocyte maturation
728554,0,0,0,0,1,0,16,0,6,0,0,0,LOC728554;THO complex 3 pseudogene,-,-,-,K12880//RNA transport;Spliceosome
728577,1,0,0,0,0,26,0,0,0,0,0,0,CNTNAP3B;contactin associated protein-like 3B,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,-,K07380//Cell adhesion molecules (CAMs)
728591,0,0,0,0,25,0,0,0,0,0,0,0,CCDC169;coiled-coil domain containing 169,-,-,-,-
728597,0,0,0,0,0,18,0,0,37,0,8,0,DCDC2C;doublecortin domain containing 2C,-,GO:0035556//intracellular signal transduction,-,-
7286,0,0,0,0,0,8,26,0,0,0,0,0,TUFT1;tuftelin 1,GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0030282//bone mineralization;GO:0042476//odontogenesis,GO:0030345//structural constituent of tooth enamel,K11447//Transcriptional misregulation in cancer;K06674//Cell cycle - yeast
728609,0,0,0,0,0,0,6,0,0,0,0,0,"SDHAP3;succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3",-,-,-,K00234//Biosynthesis of secondary metabolites;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease;Citrate cycle (TCA cycle);Metabolic pathways
728619,0,0,0,7,0,1,45,0,0,0,5,0,ASB9P1;ankyrin repeat and SOCS box containing 9 pseudogene 1,-,-,-,-
728621,0,0,1,3,0,0,27,0,15,0,0,0,CCDC30;coiled-coil domain containing 30,GO:0070062//extracellular vesicular exosome,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K06267//ECM-receptor interaction;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways
728622,0,0,0,0,0,14,0,0,15,0,0,0,SKP1P2;S-phase kinase-associated protein 1 pseudogene 2,-,-,-,K03094//Oocyte meiosis;Wnt signaling pathway;Herpes simplex infection;Protein processing in endoplasmic reticulum;Cell cycle;Cell cycle - yeast;TGF-beta signaling pathway;Ubiquitin mediated proteolysis;Circadian rhythm - mammal
728635,0,0,0,0,1,0,0,0,40,0,0,0,DHRS4L1;dehydrogenase/reductase (SDR family) member 4 like 1,-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K11147//Peroxisome;Retinol metabolism;Metabolic pathways
728640,0,0,0,0,0,0,0,0,41,0,0,0,"FAM133CP;family with sequence similarity 133, member A pseudogene",-,-,-,-
728642,0,0,0,0,0,0,1,0,26,0,1,0,CDK11A;cyclin-dependent kinase 11A,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006468//protein phosphorylation;GO:0050684//regulation of mRNA processing;GO:0007067//mitotic nuclear division;GO:0006355//regulation of transcription, DNA-templated;GO:0051726//regulation of cell cycle;GO:0001558//regulation of cell growth;GO:0006915//apoptotic process",GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005524//ATP binding,-
728643,0,0,0,0,0,0,7,0,0,0,0,0,HNRNPA1P33;heterogeneous nuclear ribonucleoprotein A1 pseudogene 33,-,-,-,K12741//Spliceosome
728661,74,66,1,21,20,0,21,0,14,122,1,0,"SLC35E2B;solute carrier family 35, member E2B",GO:0016021//integral component of membrane,-,-,-
728689,0,0,0,0,0,0,0,0,2,0,0,0,"EIF3CL;eukaryotic translation initiation factor 3, subunit C-like",GO:0016282//eukaryotic 43S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0033290//eukaryotic 48S preinitiation complex,GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex,GO:0031369//translation initiation factor binding;GO:0003743//translation initiation factor activity,K03252//RNA transport
728695,0,0,0,0,0,1,0,0,2,0,0,0,"SPANXB1;SPANX family, member B1",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007286//spermatid development,-,-
7287,55,0,0,0,10,6,29,57,0,0,12,0,TULP1;tubby like protein 1,GO:0005737//cytoplasm;GO:0001750//photoreceptor outer segment;GO:0001917//photoreceptor inner segment;GO:0005576//extracellular region;GO:0045202//synapse;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0042995//cell projection,GO:0007601//visual perception;GO:0016358//dendrite development;GO:0050766//positive regulation of phagocytosis;GO:0042462//eye photoreceptor cell development;GO:0060041//retina development in camera-type eye;GO:0006909//phagocytosis;GO:0045494//photoreceptor cell maintenance;GO:0050908//detection of light stimulus involved in visual perception;GO:0007602//phototransduction;GO:0001895//retina homeostasis,"GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0008020//G-protein coupled photoreceptor activity;GO:0051015//actin filament binding;GO:0005515//protein binding",-
728741,4,0,0,0,0,0,0,1,5,0,0,0,"NPIPB6;nuclear pore complex interacting protein family, member B6",-,-,-,K01896//Butanoate metabolism;Lipoic acid metabolism;Metabolic pathways
728747,0,0,0,0,0,0,27,5,8,4,0,88,"ANKRD20A4;ankyrin repeat domain 20 family, member A4",-,-,-,-
728752,53,0,0,13,8,3,0,0,0,0,6,1,LOC728752;uncharacterized LOC728752,-,-,-,-
728758,0,0,0,0,0,0,0,82,12,0,0,0,"PIN4P1;protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 pseudogene 1",-,-,-,-
728773,0,0,0,0,0,0,0,0,21,127,0,0,"PABPC1P2;poly(A) binding protein, cytoplasmic 1 pseudogene 2",-,-,-,K13126//RNA degradation;RNA transport;mRNA surveillance pathway
728780,94,2,0,3,0,11,0,0,44,0,0,0,ANKDD1B;ankyrin repeat and death domain containing 1B,-,GO:0007165//signal transduction,-,-
728798,0,0,0,1,1,0,38,0,20,0,0,0,FRMPD2P1;FERM and PDZ domain containing 2 pseudogene 1,-,-,-,-
7288,0,0,0,0,0,3,0,0,11,58,0,0,TULP2;tubby like protein 2,GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0007601//visual perception,GO:0032403//protein complex binding,-
728806,0,0,0,0,9,0,0,0,0,0,0,0,NSFP1;N-ethylmaleimide-sensitive factor pseudogene 1,-,-,-,K06027//Synaptic vesicle cycle;Vasopressin-regulated water reabsorption;GABAergic synapse
728819,0,0,0,0,0,0,0,0,7,0,0,0,LOC728819;hCG1645220,-,-,-,K09653//Metabolic pathways;Mucin type O-Glycan biosynthesis
728841,60,4,0,1,42,19,22,8,25,1,0,0,"NBPF8;neuroblastoma breakpoint family, member 8",GO:0005737//cytoplasm,-,-,-
728855,0,3,0,0,0,1,0,0,0,0,0,0,LINC00623;long intergenic non-protein coding RNA 623,-,-,-,-
728858,0,0,0,0,0,0,30,0,0,0,0,0,C12orf71;chromosome 12 open reading frame 71,-,-,-,-
7289,0,0,0,0,9,33,0,0,26,0,0,0,TULP3;tubby like protein 3,GO:0072372//primary cilium;GO:0005730//nucleolus;GO:0005929//cilium;GO:0005634//nucleus;GO:0005930//axoneme;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0097546//ciliary base;GO:0030991//intraciliary transport particle A,"GO:0006355//regulation of transcription, DNA-templated;GO:0048702//embryonic neurocranium morphogenesis;GO:0045879//negative regulation of smoothened signaling pathway;GO:0021953//central nervous system neuron differentiation;GO:0007420//brain development;GO:0007186//G-protein coupled receptor signaling pathway;GO:1901621//negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0060831//smoothened signaling pathway involved in dorsal/ventral neural tube patterning;GO:0042733//embryonic digit morphogenesis;GO:0001843//neural tube closure;GO:0009952//anterior/posterior pattern specification;GO:0031076//embryonic camera-type eye development;GO:0060348//bone development;GO:0060434//bronchus morphogenesis;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0021914//negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning","GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0032403//protein complex binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0019899//enzyme binding",-
728927,48,0,0,5,42,12,0,0,52,0,0,9,ZNF736;zinc finger protein 736,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
728989,0,0,0,0,0,0,30,0,8,36,1,0,LOC728989;phosphodiesterase 4D interacting protein pseudogene,-,-,-,-
729,0,0,0,0,0,15,13,0,83,0,0,0,C6;complement component 6,GO:0005579//membrane attack complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0030449//regulation of complement activation;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response;GO:0001701//in utero embryonic development;GO:0019835//cytolysis;GO:0006956//complement activation",GO:0005515//protein binding,K03995//Systemic lupus erythematosus;Prion diseases;Complement and coagulation cascades
7290,67,0,1,15,26,46,1,0,13,0,121,0,HIRA;histone cell cycle regulator,GO:0016605//PML body;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0006336//DNA replication-independent nucleosome assembly;GO:0001649//osteoblast differentiation;GO:0007369//gastrulation;GO:0042692//muscle cell differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity,-
729020,0,0,0,0,0,28,2,0,0,0,0,0,RPEL1;ribulose-5-phosphate-3-epimerase-like 1,-,GO:0006098//pentose-phosphate shunt,GO:0004750//ribulose-phosphate 3-epimerase activity;GO:0046872//metal ion binding,K01783//Pentose phosphate pathway;Pentose and glucuronate interconversions;Metabolic pathways;Purine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms;Pyrimidine metabolism
729025,0,0,0,0,0,5,15,0,34,301,0,19,"SLC15A5;solute carrier family 15, member 5",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0015031//protein transport;GO:0015833//peptide transport,GO:0015293//symporter activity,-
729041,0,0,0,0,0,0,0,0,6,107,0,1,FAAHP1;fatty acid amide hydrolase pseudogene 1,-,-,-,K15528//Retrograde endocannabinoid signaling
729080,69,0,0,0,0,0,0,0,18,1,0,393,LOC729080;glycine cleavage system protein H (aminomethyl carrier) pseudogene,-,-,-,K02437//Glyoxylate and dicarboxylate metabolism;Biosynthesis of secondary metabolites;Ribosome
729082,0,0,0,0,0,0,0,0,1,0,0,0,OIP5-AS1;OIP5 antisense RNA 1,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K11447//Transcriptional misregulation in cancer
729085,103,0,0,0,0,0,0,3,13,0,13,0,"FAM198A;family with sequence similarity 198, member A",GO:0005576//extracellular region,-,-,-
729092,0,0,0,0,0,0,10,1,8,0,0,0,"AGAP5;ArfGAP with GTPase domain, ankyrin repeat and PH domain 5",-,GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12491//Endocytosis
729096,0,0,0,0,20,0,26,0,26,142,0,0,BMS1P4;BMS1 pseudogene 4,-,-,-,K14569//Ribosome biogenesis in eukaryotes
7291,0,0,0,0,0,0,0,0,25,0,2,0,TWIST1;twist family bHLH transcription factor 1,GO:0005634//nucleus,"GO:0048642//negative regulation of skeletal muscle tissue development;GO:0007517//muscle organ development;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0032720//negative regulation of tumor necrosis factor production;GO:0035115//embryonic forelimb morphogenesis;GO:0001764//neuron migration;GO:0001843//neural tube closure;GO:0003183//mitral valve morphogenesis;GO:0003180//aortic valve morphogenesis;GO:2000780//negative regulation of double-strand break repair;GO:0001649//osteoblast differentiation;GO:0060021//palate development;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0050679//positive regulation of epithelial cell proliferation;GO:0035067//negative regulation of histone acetylation;GO:0060363//cranial suture morphogenesis;GO:2000276//negative regulation of oxidative phosphorylation uncoupler activity;GO:2000147//positive regulation of cell motility;GO:2000773//negative regulation of cellular senescence;GO:0035116//embryonic hindlimb morphogenesis;GO:0060900//embryonic camera-type eye formation;GO:0061029//eyelid development in camera-type eye;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:2000778//positive regulation of interleukin-6 secretion;GO:0071363//cellular response to growth factor stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045668//negative regulation of osteoblast differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0035359//negative regulation of peroxisome proliferator activated receptor signaling pathway;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0033128//negative regulation of histone phosphorylation;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0042476//odontogenesis;GO:0003203//endocardial cushion morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042473//outer ear morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0030500//regulation of bone mineralization;GO:0071456//cellular response to hypoxia;GO:0045766//positive regulation of angiogenesis;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001503//ossification;GO:0001701//in utero embryonic development",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0070888//E-box binding;GO:0008134//transcription factor binding;GO:0019904//protein domain specific binding;GO:0043425//bHLH transcription factor binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
729156,0,132,279,283,230,0,2,1,23,0,225,0,GTF2IRD1P1;GTF2I repeat domain containing 1 pseusogene 1,-,-,-,K03121//Herpes simplex infection;Basal transcription factors
729159,0,0,0,0,0,0,0,0,22,1,11,0,LOC729159;UPF0607 protein ENSP00000381418-like,-,-,-,K14316//RNA transport
729171,0,0,0,0,0,11,0,0,76,0,8,0,"ANKRD20A8P;ankyrin repeat domain 20 family, member A8, pseudogene",-,-,-,-
7292,0,17,0,0,11,0,0,0,1,218,0,0,"TNFSF4;tumor necrosis factor (ligand) superfamily, member 4",GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,"GO:0032753//positive regulation of interleukin-4 production;GO:0032729//positive regulation of interferon-gamma production;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0050710//negative regulation of cytokine secretion;GO:0002726//positive regulation of T cell cytokine production;GO:0051024//positive regulation of immunoglobulin secretion;GO:0032733//positive regulation of interleukin-10 production;GO:0050727//regulation of inflammatory response;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0008203//cholesterol metabolic process;GO:0045590//negative regulation of regulatory T cell differentiation;GO:0032755//positive regulation of interleukin-6 production;GO:0043382//positive regulation of memory T cell differentiation;GO:0007165//signal transduction;GO:0042104//positive regulation of activated T cell proliferation;GO:1900281//positive regulation of CD4-positive, alpha-beta T cell costimulation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:2000570//positive regulation of T-helper 2 cell activation;GO:0042098//T cell proliferation;GO:0032736//positive regulation of interleukin-13 production;GO:0008284//positive regulation of cell proliferation;GO:0002215//defense response to nematode;GO:0032689//negative regulation of interferon-gamma production;GO:0050871//positive regulation of B cell activation;GO:0002819//regulation of adaptive immune response;GO:0035714//cellular response to nitrogen dioxide;GO:0002891//positive regulation of immunoglobulin mediated immune response;GO:0006955//immune response;GO:2000568//positive regulation of memory T cell activation;GO:0009615//response to virus;GO:0071380//cellular response to prostaglandin E stimulus;GO:0002526//acute inflammatory response;GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0032735//positive regulation of interleukin-12 production;GO:0032700//negative regulation of interleukin-17 production;GO:2000572//positive regulation of interleukin-4-dependent isotype switching to IgE isotypes;GO:0050729//positive regulation of inflammatory response;GO:0032743//positive regulation of interleukin-2 production;GO:0045626//negative regulation of T-helper 1 cell differentiation;GO:0002830//positive regulation of type 2 immune response;GO:0071954//chemokine (C-C motif) ligand 11 production",GO:0005102//receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding,K05469//Cytokine-cytokine receptor interaction
729218,79,0,53,0,0,0,0,0,56,172,16,0,LOC729218;uncharacterized LOC729218,-,-,-,K04006//Viral myocarditis;Hematopoietic cell lineage;Complement and coagulation cascades
729230,0,0,0,0,0,0,0,0,3,0,0,0,CCR2;chemokine (C-C motif) receptor 2,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0043204//perikaryon,"GO:0019221//cytokine-mediated signaling pathway;GO:0002829//negative regulation of type 2 immune response;GO:0006968//cellular defense response;GO:0070098//chemokine-mediated signaling pathway;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0006954//inflammatory response;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0035705//T-helper 17 cell chemotaxis;GO:0001974//blood vessel remodeling;GO:0010574//regulation of vascular endothelial growth factor production;GO:0006874//cellular calcium ion homeostasis;GO:0032729//positive regulation of interferon-gamma production;GO:0032743//positive regulation of interleukin-2 production;GO:2000464//positive regulation of astrocyte chemotaxis;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006935//chemotaxis;GO:0010820//positive regulation of T cell chemotaxis;GO:0050729//positive regulation of inflammatory response;GO:0007259//JAK-STAT cascade;GO:2000439//positive regulation of monocyte extravasation;GO:0019725//cellular homeostasis;GO:2000473//positive regulation of hematopoietic stem cell migration;GO:0009611//response to wounding;GO:0002407//dendritic cell chemotaxis;GO:0016032//viral process;GO:0016525//negative regulation of angiogenesis;GO:0090265//positive regulation of immune complex clearance by monocytes and macrophages;GO:0090026//positive regulation of monocyte chemotaxis;GO:0006955//immune response;GO:0043310//negative regulation of eosinophil degranulation;GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:2000451//positive regulation of CD8-positive, alpha-beta T cell extravasation;GO:0045087//innate immune response;GO:0050870//positive regulation of T cell activation;GO:0007204//positive regulation of cytosolic calcium ion concentration",GO:0042803//protein homodimerization activity;GO:0004950//chemokine receptor activity;GO:0031727//CCR2 chemokine receptor binding;GO:0016493//C-C chemokine receptor activity,K04177//Chemokine signaling pathway;Cytokine-cytokine receptor interaction
729234,0,0,0,0,0,0,0,0,0,0,12,0,"FAHD2CP;fumarylacetoacetate hydrolase domain containing 2C, pseudogene",-,-,-,K00629//Glycerophospholipid metabolism;Glycerolipid metabolism;Metabolic pathways;K01557//Metabolic pathways;Tyrosine metabolism
729238,0,1,0,0,0,0,37,0,33,0,0,0,SFTPA2;surfactant protein A2,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005581//collagen trimer;GO:0005578//proteinaceous extracellular matrix,GO:0007585//respiratory gaseous exchange,GO:0030246//carbohydrate binding,K10067//Phagosome;Pertussis
729252,1,0,20,0,0,13,8,62,29,0,25,0,KRT16P1;keratin 16 pseudogene 1,-,-,-,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
729262,0,0,0,0,0,12,21,34,51,2,0,0,NUTM2B;NUT family member 2B,-,-,-,-
729264,0,0,0,0,0,0,0,1,10,0,0,0,TP53TG3D;TP53 target 3D,-,-,-,-
729288,0,21,0,0,0,0,0,0,14,0,0,0,ZNF286B;zinc finger protein 286B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7293,0,0,0,0,0,0,0,0,7,0,3,0,"TNFRSF4;tumor necrosis factor receptor superfamily, member 4",GO:0009986//cell surface;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,"GO:0050710//negative regulation of cytokine secretion;GO:0042981//regulation of apoptotic process;GO:0006954//inflammatory response;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042098//T cell proliferation;GO:0045859//regulation of protein kinase activity;GO:0030890//positive regulation of B cell proliferation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0006968//cellular defense response;GO:0006955//immune response;GO:0051024//positive regulation of immunoglobulin secretion;GO:0045892//negative regulation of transcription, DNA-templated",GO:0005031//tumor necrosis factor-activated receptor activity,K05142//Cytokine-cytokine receptor interaction
729330,18,0,0,0,0,19,0,0,16,0,7,160,OC90;otoconin 90,GO:0005576//extracellular region,GO:0016042//lipid catabolic process;GO:0006644//phospholipid metabolic process,GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity,K01047//GnRH signaling pathway;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;Linoleic acid metabolism;MAPK signaling pathway;Glutamatergic synapse;Metabolic pathways;Vascular smooth muscle contraction;Fc epsilon RI signaling pathway;Long-term depression;Fc gamma R-mediated phagocytosis;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism
729359,0,0,0,0,0,8,21,68,48,0,14,0,PLIN4;perilipin 4,GO:0005886//plasma membrane;GO:0005811//lipid particle;GO:0005737//cytoplasm,-,-,K10955//Vibrio cholerae infection;Amoebiasis
729384,4,0,0,0,0,0,0,0,0,0,0,0,"TRIM49D2P;tripartite motif containing 49D2, pseudogene",GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
7294,0,0,0,0,0,12,22,0,47,0,3,0,TXK;TXK tyrosine kinase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane,"GO:0006351//transcription, DNA-templated;GO:0002250//adaptive immune response;GO:0032633//interleukin-4 production;GO:0032609//interferon-gamma production;GO:0050852//T cell receptor signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0001816//cytokine production;GO:0006468//protein phosphorylation;GO:0007202//activation of phospholipase C activity;GO:0032729//positive regulation of interferon-gamma production;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0001865//NK T cell differentiation",GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0001012//RNA polymerase II regulatory region DNA binding;GO:0005515//protein binding,K08016//Leukocyte transendothelial migration
729438,1,0,0,0,0,2,16,101,24,0,0,9,GATSL2;GATS protein-like 2,-,-,-,K11447//Transcriptional misregulation in cancer
729440,0,0,0,0,1,0,0,0,1,0,0,0,CCDC61;coiled-coil domain containing 61,GO:0005813//centrosome,-,-,-
729447,0,0,0,0,0,0,0,0,1,0,0,0,GAGE2A;G antigen 2A,-,-,-,-
729475,0,0,0,0,0,1,0,0,27,0,9,0,RAD51AP2;RAD51 associated protein 2,-,-,-,-
7295,0,120,1,58,191,7,0,62,7,0,0,0,TXN;thioredoxin,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,"GO:0008283//cell proliferation;GO:0006351//transcription, DNA-templated;GO:0043388//positive regulation of DNA binding;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045087//innate immune response;GO:0033158//regulation of protein import into nucleus, translocation;GO:0015949//nucleobase-containing small molecule interconversion;GO:0007267//cell-cell signaling;GO:0044281//small molecule metabolic process;GO:0055114//oxidation-reduction process;GO:0009314//response to radiation;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0006928//cellular component movement;GO:0045454//cell redox homeostasis;GO:0046826//negative regulation of protein export from nucleus;GO:0006662//glycerol ether metabolic process;GO:0007165//signal transduction",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0015035//protein disulfide oxidoreductase activity;GO:0015037//peptide disulfide oxidoreductase activity,K03671//Pyrimidine metabolism;Selenocompound metabolism
729515,0,31,0,3,14,53,0,0,17,0,2,253,TMEM242;transmembrane protein 242,GO:0016021//integral component of membrane,-,-,-
729522,0,0,0,0,0,0,2,0,0,6,0,0,AACSP1;acetoacetyl-CoA synthetase pseudogene 1,-,-,-,K01907//Butanoate metabolism
729574,11,0,0,0,0,0,19,0,11,6,1,0,"FAM231A;family with sequence similarity 231, member A",-,-,-,-
729597,0,3,29,11,29,1,0,2,2,5,11,0,SPDYE6;speedy/RINGO cell cycle regulator family member E6,-,-,-,K08694//Progesterone-mediated oocyte maturation;Oocyte meiosis
7296,0,17,1,0,11,0,15,0,21,0,0,0,TXNRD1;thioredoxin reductase 1,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus,GO:0045454//cell redox homeostasis;GO:0055114//oxidation-reduction process;GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0015949//nucleobase-containing small molecule interconversion;GO:0044255//cellular lipid metabolic process;GO:0001707//mesoderm formation,GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding;GO:0005515//protein binding;GO:0009055//electron carrier activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0004791//thioredoxin-disulfide reductase activity,K00384//Selenocompound metabolism;Pyrimidine metabolism;Two-component system
729603,188,0,0,0,0,0,0,0,19,0,0,0,LOC729603;calcineurin-like EF-hand protein 1 pseudogene,-,-,-,K06268//Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Oocyte meiosis;Amphetamine addiction;Apoptosis;Glutamatergic synapse;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;Long-term potentiation;Tuberculosis;Axon guidance;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation;B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection
729614,0,72,0,77,124,0,0,69,30,0,43,631,FLJ37453;uncharacterized LOC729614,-,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
729627,0,0,0,0,0,2,34,0,0,24,0,0,PRR23A;proline rich 23A,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
729648,0,1,0,0,29,0,23,0,12,140,10,0,ZNF812;zinc finger protein 812,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
729665,0,0,0,0,0,14,0,0,65,0,0,0,CCDC175;coiled-coil domain containing 175,-,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton
729668,0,0,1,0,0,11,23,0,37,0,8,0,GOLGA2P6;golgin A2 pseudogene 6,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
729689,0,0,0,0,0,0,0,3,0,0,0,0,"FAM90A2P;family with sequence similarity 90, member A2 pseudogene",-,-,-,-
7297,0,0,0,0,2,5,14,45,78,0,0,0,TYK2;tyrosine kinase 2,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton,GO:0019221//cytokine-mediated signaling pathway;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060337//type I interferon signaling pathway,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005131//growth hormone receptor binding;GO:0031702//type 1 angiotensin receptor binding;GO:0005515//protein binding,K11219//Epstein-Barr virus infection;Measles;Hepatitis C;Osteoclast differentiation;Toxoplasmosis;Herpes simplex infection;Influenza A;Jak-STAT signaling pathway
729732,3,0,0,0,0,0,32,0,17,29,1,0,LOC729732;uncharacterized LOC729732,-,-,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
729737,0,0,1,0,0,8,1,0,13,0,0,0,LOC729737;uncharacterized LOC729737,-,-,-,K05185//Neuroactive ligand-receptor interaction;Retrograde endocannabinoid signaling;Nicotine addiction;Morphine addiction;GABAergic synapse
729747,0,0,0,0,0,2,22,0,0,0,1,0,ZNF878;zinc finger protein 878,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
729767,82,0,0,0,0,2,0,0,31,0,0,0,CEACAM18;carcinoembryonic antigen-related cell adhesion molecule 18,-,-,-,-
729786,3,0,0,0,0,3,1,57,11,0,0,4,"GOLGA8CP;golgin A8 family, member C, pseudogene",GO:0005794//Golgi apparatus,-,-,-
729799,0,0,0,0,0,0,19,0,0,0,8,0,SEC14L1P1;SEC14-like 1 pseudogene 1,-,-,-,-
7298,0,0,46,77,119,0,0,0,29,0,62,0,TYMS;thymidylate synthetase,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005654//nucleoplasm,GO:0060574//intestinal epithelial cell maturation;GO:0031100//organ regeneration;GO:0006231//dTMP biosynthetic process;GO:0042493//response to drug;GO:0006235//dTTP biosynthetic process;GO:0009636//response to toxic substance;GO:0051216//cartilage development;GO:0032259//methylation;GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0009157//deoxyribonucleoside monophosphate biosynthetic process;GO:0005976//polysaccharide metabolic process;GO:0046078//dUMP metabolic process;GO:0045471//response to ethanol;GO:0051593//response to folic acid;GO:0007568//aging;GO:0000082//G1/S transition of mitotic cell cycle;GO:0046683//response to organophosphorus;GO:0019860//uracil metabolic process;GO:0032570//response to progesterone;GO:0033189//response to vitamin A;GO:0048589//developmental growth;GO:0046653//tetrahydrofolate metabolic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0034097//response to cytokine;GO:0006139//nucleobase-containing compound metabolic process;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0019088//immortalization of host cell by virus;GO:0007623//circadian rhythm;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0004799//thymidylate synthase activity;GO:0008144//drug binding;GO:0000166//nucleotide binding;GO:0042803//protein homodimerization activity;GO:0048037//cofactor binding;GO:0003729//mRNA binding;GO:0005542//folic acid binding,K00560//Metabolic pathways;One carbon pool by folate;Pyrimidine metabolism;Homologous recombination
729830,0,0,0,0,13,10,49,0,43,0,0,0,"FAM160A1;family with sequence similarity 160, member A1",-,-,-,-
729862,0,0,0,27,0,0,0,0,0,0,31,0,LSP1P3;lymphocyte-specific protein 1 pseudogene 3,-,-,-,K14957//Tuberculosis
729873,0,0,0,0,0,0,0,0,0,5,0,0,"TBC1D3;TBC1 domain family, member 3",GO:0005886//plasma membrane,GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly,GO:0005097//Rab GTPase activator activity,-
7299,0,0,0,0,0,23,0,0,26,0,0,0,TYR;tyrosinase,GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0033162//melanosome membrane;GO:0005737//cytoplasm;GO:0005764//lysosome;GO:0005798//Golgi-associated vesicle,GO:0007601//visual perception;GO:0048538//thymus development;GO:0008283//cell proliferation;GO:0006726//eye pigment biosynthetic process;GO:0055114//oxidation-reduction process;GO:0006583//melanin biosynthetic process from tyrosine,GO:0005507//copper ion binding;GO:0004503//monophenol monooxygenase activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K00505//Biosynthesis of secondary metabolites;Melanogenesis;Riboflavin metabolism;Metabolic pathways;Tyrosine metabolism
729920,0,0,0,0,20,13,43,0,16,35,11,0,ISPD;isoprenoid synthase domain containing,-,GO:0035269//protein O-linked mannosylation;GO:0008299//isoprenoid biosynthetic process;GO:0007411//axon guidance,GO:0016779//nucleotidyltransferase activity,-
729930,0,0,0,0,0,0,0,0,1,0,0,0,LOC729930;chromosome 11 open reading frame 74 pseudogene,-,-,-,-
729956,0,0,0,0,0,18,0,0,8,1,0,1,SHISA7;shisa family member 7,GO:0016021//integral component of membrane,-,-,K02327//DNA replication;Metabolic pathways;Purine metabolism;HTLV-I infection;Nucleotide excision repair;Homologous recombination;Base excision repair;Pyrimidine metabolism;Mismatch repair;K10583//Ubiquitin mediated proteolysis
729966,0,0,0,0,0,0,20,0,33,0,0,0,LOC729966;uncharacterized LOC729966,-,-,-,-
729967,0,0,0,12,60,0,0,0,0,0,0,0,MORN2;MORN repeat containing 2,-,-,-,K04575//Amyotrophic lateral sclerosis (ALS)
729974,0,0,0,0,0,1,0,0,0,0,0,0,RFPL4AL1;ret finger protein-like 4A-like 1,-,-,GO:0008270//zinc ion binding,-
729975,0,16,50,9,15,0,0,0,0,0,16,0,FLJ30403;uncharacterized LOC729975,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
729991,0,0,0,0,1,0,0,0,0,0,0,0,MEF2BNB;MEF2B neighbor,-,GO:0007507//heart development,GO:0005515//protein binding,K14443//RNA degradation;K00797//Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;Metabolic pathways;beta-Alanine metabolism
729993,0,4,0,0,0,16,13,0,8,0,13,148,SHISA9;shisa family member 9,GO:0030054//cell junction;GO:0045202//synapse;GO:0032591//dendritic spine membrane;GO:0008328//ionotropic glutamate receptor complex,GO:0048172//regulation of short-term neuronal synaptic plasticity,-,K11447//Transcriptional misregulation in cancer;K04257//Olfactory transduction;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
730,0,0,0,0,0,13,0,0,18,0,5,0,C7;complement component 7,GO:0005579//membrane attack complex;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,"GO:0030449//regulation of complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0006883//cellular sodium ion homeostasis;GO:0045087//innate immune response;GO:0019835//cytolysis;GO:0006956//complement activation",-,K03996//Systemic lupus erythematosus;Prion diseases;Complement and coagulation cascades
730005,92,0,0,0,0,1,0,48,7,0,7,0,SEC14L6;SEC14-like 6 (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0006810//transport,GO:0005215//transporter activity,-
730051,0,1,19,39,59,4,0,0,0,0,42,0,ZNF814;zinc finger protein 814,GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
730092,0,0,0,0,0,12,0,44,17,0,0,0,RRN3P1;RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1,-,-,-,-
730094,0,0,0,0,0,0,0,0,18,0,0,0,C16orf52;chromosome 16 open reading frame 52,-,-,-,-
7301,19,0,0,0,0,9,26,6,28,0,7,0,TYRO3;TYRO3 protein tyrosine kinase,GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0005635//nuclear envelope;GO:0005634//nucleus,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0070527//platelet aggregation;GO:0043277//apoptotic cell clearance;GO:0014065//phosphatidylinositol 3-kinase signaling;GO:0051250//negative regulation of lymphocyte activation;GO:0034122//negative regulation of toll-like receptor signaling pathway;GO:0060068//vagina development;GO:0043491//protein kinase B signaling;GO:0045824//negative regulation of innate immune response;GO:0050728//negative regulation of inflammatory response;GO:0007283//spermatogenesis;GO:0007155//cell adhesion;GO:0021885//forebrain cell migration;GO:0070050//neuron cellular homeostasis;GO:0023014//signal transduction by phosphorylation;GO:0007165//signal transduction;GO:0034446//substrate adhesion-dependent cell spreading;GO:0046777//protein autophosphorylation;GO:0030168//platelet activation;GO:0032940//secretion by cell;GO:0043524//negative regulation of neuron apoptotic process;GO:0001779//natural killer cell differentiation;GO:0042698//ovulation cycle,GO:0005524//ATP binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0004714//transmembrane receptor protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0046982//protein heterodimerization activity;GO:0004716//receptor signaling protein tyrosine kinase activity;GO:0005515//protein binding,-
730102,0,13,1,8,40,9,0,0,11,0,0,0,LOC730102;quinone oxidoreductase-like protein 2 pseudogene,-,-,-,K00344//Fatty acid metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Naphthalene degradation;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments
730112,0,0,0,0,0,0,0,0,37,0,0,0,"FAM166B;family with sequence similarity 166, member B",-,-,-,-
730130,0,0,0,0,10,0,0,61,0,0,0,0,TMEM229A;transmembrane protein 229A,GO:0016021//integral component of membrane,"GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity,-
730159,0,0,0,0,0,5,0,0,0,0,0,0,LOC730159;uncharacterized LOC730159,-,-,-,-
730183,0,27,48,42,70,0,0,67,22,0,36,0,LOC730183;uncharacterized LOC730183,-,-,-,-
7302,0,0,0,0,0,0,0,0,13,0,0,0,TYRO3P;TYRO3P protein tyrosine kinase pseudogene,-,-,-,-
730249,0,0,0,0,0,0,0,34,8,0,0,0,IRG1;immunoresponsive 1 homolog (mouse),GO:0005739//mitochondrion,GO:0050728//negative regulation of inflammatory response;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045824//negative regulation of innate immune response;GO:0002760//positive regulation of antimicrobial humoral response;GO:0071347//cellular response to interleukin-1;GO:0071393//cellular response to progesterone stimulus;GO:0019543//propionate catabolic process;GO:0071222//cellular response to lipopolysaccharide;GO:0071356//cellular response to tumor necrosis factor;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0071346//cellular response to interferon-gamma;GO:0071219//cellular response to molecule of bacterial origin;GO:0006954//inflammatory response;GO:0008152//metabolic process;GO:0007566//embryo implantation;GO:0034136//negative regulation of toll-like receptor 2 signaling pathway;GO:0072573//tolerance induction to lipopolysaccharide;GO:0032480//negative regulation of type I interferon production;GO:0006952//defense response;GO:0035458//cellular response to interferon-beta,GO:0047613//aconitate decarboxylase activity;GO:0047547//2-methylcitrate dehydratase activity,-
730291,0,0,0,0,0,0,0,37,2,0,10,0,"ZNF735P;zinc finger protein 735, pseudogene",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
730394,0,0,0,0,0,0,0,0,0,0,0,404,"GTF2H2C_2;GTF2H2 family member C, copy 2",GO:0000439//core TFIIH complex,"GO:0006351//transcription, DNA-templated;GO:0006289//nucleotide-excision repair;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding,K03142//Nucleotide excision repair;Basal transcription factors
7305,0,0,0,0,0,0,0,0,6,0,11,0,TYROBP;TYRO protein tyrosine kinase binding protein,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface,GO:0006968//cellular defense response;GO:0002281//macrophage activation involved in immune response;GO:0007411//axon guidance;GO:0035556//intracellular signal transduction;GO:0050776//regulation of immune response;GO:0045087//innate immune response;GO:0007229//integrin-mediated signaling pathway;GO:0007165//signal transduction;GO:2001204//regulation of osteoclast development;GO:0002283//neutrophil activation involved in immune response,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0005057//receptor signaling protein activity;GO:0005102//receptor binding,K07992//Osteoclast differentiation;Natural killer cell mediated cytotoxicity
7306,0,0,0,0,0,7,0,0,65,43,12,16,TYRP1;tyrosinase-related protein 1,GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0033162//melanosome membrane;GO:0042470//melanosome;GO:0010008//endosome membrane;GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0042438//melanin biosynthetic process;GO:0030318//melanocyte differentiation;GO:0032438//melanosome organization;GO:0043438//acetoacetic acid metabolic process,"GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0016716//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen;GO:0005507//copper ion binding",K00506//Metabolic pathways;Tyrosine metabolism;Melanogenesis
730668,0,0,0,0,0,52,5,0,24,0,0,0,LOC730668;dynein heavy chain -like pseudogene,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K03914//Regulation of actin cytoskeleton;Endocytosis;Calcium signaling pathway;Neuroactive ligand-receptor interaction;Complement and coagulation cascades;K06264//ECM-receptor interaction
7307,0,0,0,18,17,0,14,0,22,0,0,0,U2AF1;U2 small nuclear RNA auxiliary factor 1,GO:0005654//nucleoplasm;GO:0015030//Cajal body;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0071013//catalytic step 2 spliceosome;GO:0005730//nucleolus;GO:0005681//spliceosomal complex,"GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0006369//termination of RNA polymerase II transcription",GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12836//Shigellosis;Spliceosome
731,0,0,0,0,0,53,0,0,36,0,11,0,"C8A;complement component 8, alpha polypeptide",GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005579//membrane attack complex,"GO:0045087//innate immune response;GO:0006956//complement activation;GO:0019835//cytolysis;GO:0006955//immune response;GO:0030449//regulation of complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway",GO:0001848//complement binding;GO:0032403//protein complex binding,K03997//Prion diseases;Systemic lupus erythematosus;Complement and coagulation cascades;Amoebiasis
7311,0,4,4,5,39,22,0,0,15,0,8,0,UBA52;ubiquitin A-52 residue ribosomal protein fusion product 1,GO:0030666//endocytic vesicle membrane;GO:0005840//ribosome;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005765//lysosomal membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0005654//nucleoplasm,"GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0007220//Notch receptor processing;GO:0055085//transmembrane transport;GO:0032480//negative regulation of type I interferon production;GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019058//viral life cycle;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006464//cellular protein modification process;GO:0019068//virion assembly;GO:0044267//cellular protein metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0034220//ion transmembrane transport;GO:0006413//translational initiation;GO:0016071//mRNA metabolic process;GO:0007219//Notch signaling pathway;GO:0042981//regulation of apoptotic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0000209//protein polyubiquitination;GO:0034138//toll-like receptor 3 signaling pathway;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0050852//T cell receptor signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0097190//apoptotic signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006415//translational termination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0016070//RNA metabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0006412//translation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0061024//membrane organization;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006006//glucose metabolic process;GO:0006281//DNA repair;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0005975//carbohydrate metabolic process;GO:0034146//toll-like receptor 5 signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0019082//viral protein processing;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007254//JNK cascade;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0019083//viral transcription;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006414//translational elongation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process",GO:0005515//protein binding;GO:0003735//structural constituent of ribosome,K02927//Ribosome
731220,0,0,0,0,0,40,0,0,17,0,0,0,"RFX8;RFX family member 8, lacking RFX DNA binding domain",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,-
731275,0,0,0,0,0,0,0,0,5,0,8,0,LINC01347;long intergenic non-protein coding RNA 1347,-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K03121//Herpes simplex infection;Basal transcription factors
7314,0,110,1,87,349,0,0,0,0,0,0,0,UBB;ubiquitin B,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005654//nucleoplasm,"GO:0034146//toll-like receptor 5 signaling pathway;GO:0019082//viral protein processing;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007254//JNK cascade;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0075733//intracellular transport of virus;GO:0016197//endosomal transport;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034166//toll-like receptor 10 signaling pathway;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071456//cellular response to hypoxia;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0061024//membrane organization;GO:0019221//cytokine-mediated signaling pathway;GO:0006915//apoptotic process;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0006006//glucose metabolic process;GO:0006281//DNA repair;GO:0005975//carbohydrate metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034162//toll-like receptor 9 signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0050852//T cell receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0055085//transmembrane transport;GO:0007220//Notch receptor processing;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0019058//viral life cycle;GO:0044281//small molecule metabolic process;GO:0032480//negative regulation of type I interferon production;GO:0005978//glycogen biosynthetic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0019068//virion assembly;GO:0034220//ion transmembrane transport;GO:0007219//Notch signaling pathway;GO:0016071//mRNA metabolic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0042981//regulation of apoptotic process",GO:0005515//protein binding,K04551//Parkinson's disease
731424,0,0,0,0,18,0,0,0,0,0,0,0,LOC731424;uncharacterized LOC731424,-,-,-,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
7316,0,254,1,98,254,0,0,31,7,0,12,0,UBC;ubiquitin C,GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0030666//endocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0007254//JNK cascade;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0032481//positive regulation of type I interferon production;GO:0034146//toll-like receptor 5 signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0019082//viral protein processing;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0071456//cellular response to hypoxia;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0006006//glucose metabolic process;GO:0006281//DNA repair;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0005975//carbohydrate metabolic process;GO:0019221//cytokine-mediated signaling pathway;GO:0061024//membrane organization;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006915//apoptotic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010467//gene expression;GO:0000209//protein polyubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0016070//RNA metabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0050852//T cell receptor signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0097190//apoptotic signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0019058//viral life cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0007220//Notch receptor processing;GO:0055085//transmembrane transport;GO:0007219//Notch signaling pathway;GO:0016071//mRNA metabolic process;GO:0042981//regulation of apoptotic process;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0019068//virion assembly;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0034220//ion transmembrane transport",GO:0002020//protease binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K08770//PPAR signaling pathway
7317,1,64,2,20,174,52,18,0,44,0,0,0,UBA1;ubiquitin-like modifier activating enzyme 1,GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0030867//rough endoplasmic reticulum membrane;GO:0030057//desmosome;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0000792//heterochromatin,GO:0006974//cellular response to DNA damage stimulus;GO:0008219//cell death;GO:0016567//protein ubiquitination;GO:0019941//modification-dependent protein catabolic process,GO:0005524//ATP binding;GO:0004839//ubiquitin activating enzyme activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K03178//Parkinson's disease;Ubiquitin mediated proteolysis
731789,0,0,0,0,0,0,0,0,40,0,0,0,LINC00202-2;long intergenic non-protein coding RNA 202-2,-,-,-,-
7318,44,31,0,1,9,1,33,0,22,0,7,0,UBA7;ubiquitin-like modifier activating enzyme 7,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006464//cellular protein modification process;GO:0045087//innate immune response;GO:0019941//modification-dependent protein catabolic process;GO:0032020//ISG15-protein conjugation;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0019221//cytokine-mediated signaling pathway,GO:0004839//ubiquitin activating enzyme activity;GO:0005524//ATP binding;GO:0004842//ubiquitin-protein transferase activity;GO:0019782//ISG15 activating enzyme activity,K10698//Parkinson's disease;Ubiquitin mediated proteolysis
7319,0,0,1,25,48,18,16,54,10,0,0,0,UBE2A;ubiquitin-conjugating enzyme E2A,GO:0005829//cytosol;GO:0001741//XY body;GO:0000785//chromatin;GO:0033503//HULC complex;GO:0000790//nuclear chromatin,GO:0006281//DNA repair;GO:0001701//in utero embryonic development;GO:0008284//positive regulation of cell proliferation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0070979//protein K11-linked ubiquitination;GO:0051865//protein autoubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0033522//histone H2A ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0060135//maternal process involved in female pregnancy;GO:0000209//protein polyubiquitination;GO:0006301//postreplication repair;GO:0009411//response to UV,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K10573//Ubiquitin mediated proteolysis
732,0,0,0,0,0,10,12,0,35,0,0,0,"C8B;complement component 8, beta polypeptide",GO:0031982//vesicle;GO:0005579//membrane attack complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0016020//membrane,"GO:0006955//immune response;GO:0019835//cytolysis;GO:0006956//complement activation;GO:0045087//innate immune response;GO:0006958//complement activation, classical pathway;GO:0006957//complement activation, alternative pathway;GO:0030449//regulation of complement activation",GO:0032403//protein complex binding,K03998//Amoebiasis;Complement and coagulation cascades;Systemic lupus erythematosus;Prion diseases
7320,0,1,0,15,51,0,0,28,0,0,8,0,UBE2B;ubiquitin-conjugating enzyme E2B,GO:0001741//XY body;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0000785//chromatin;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005657//replication fork;GO:0033503//HULC complex,GO:0006281//DNA repair;GO:0051026//chiasma assembly;GO:0033128//negative regulation of histone phosphorylation;GO:0070076//histone lysine demethylation;GO:0070979//protein K11-linked ubiquitination;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0033522//histone H2A ubiquitination;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0006344//maintenance of chromatin silencing;GO:0006301//postreplication repair;GO:0001666//response to hypoxia;GO:0070193//synaptonemal complex organization;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0042493//response to drug;GO:0001701//in utero embryonic development;GO:0051865//protein autoubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0010845//positive regulation of reciprocal meiotic recombination;GO:0016567//protein ubiquitination;GO:0050821//protein stabilization;GO:0043066//negative regulation of apoptotic process;GO:0007288//sperm axoneme assembly;GO:0032869//cellular response to insulin stimulus;GO:0000209//protein polyubiquitination;GO:0060070//canonical Wnt signaling pathway;GO:0009411//response to UV,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0031625//ubiquitin protein ligase binding,K10574//Ubiquitin mediated proteolysis
7321,0,0,0,0,16,46,0,0,2,0,0,0,UBE2D1;ubiquitin-conjugating enzyme E2D 1,GO:0005829//cytosol;GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0031398//positive regulation of protein ubiquitination;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0000278//mitotic cell cycle;GO:0070936//protein K48-linked ubiquitination;GO:0007094//mitotic spindle assembly checkpoint;GO:0071456//cellular response to hypoxia;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045087//innate immune response;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030509//BMP signaling pathway;GO:0010467//gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated",GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K06689//Ubiquitin mediated proteolysis;Shigellosis;Protein processing in endoplasmic reticulum
7322,101,37,0,27,56,0,30,0,25,0,0,0,UBE2D2;ubiquitin-conjugating enzyme E2D 2,GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0045087//innate immune response;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0071456//cellular response to hypoxia;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0000209//protein polyubiquitination;GO:0002224//toll-like receptor signaling pathway;GO:0016567//protein ubiquitination;GO:0034142//toll-like receptor 4 signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0035666//TRIF-dependent toll-like receptor signaling pathway,GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K06689//Ubiquitin mediated proteolysis;Shigellosis;Protein processing in endoplasmic reticulum
7323,0,0,40,61,16,1,0,0,0,0,29,0,UBE2D3;ubiquitin-conjugating enzyme E2D 3,GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005829//cytosol,"GO:0002224//toll-like receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0030509//BMP signaling pathway;GO:0010467//gene expression;GO:0034142//toll-like receptor 4 signaling pathway;GO:0006464//cellular protein modification process;GO:0045087//innate immune response;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0071456//cellular response to hypoxia;GO:0032480//negative regulation of type I interferon production;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070979//protein K11-linked ubiquitination;GO:0006281//DNA repair;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia",GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K06689//Shigellosis;Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum
7324,0,0,1,26,19,0,0,0,0,0,14,0,UBE2E1;ubiquitin-conjugating enzyme E2E 1,GO:0005829//cytosol;GO:0000151//ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0016567//protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0070936//protein K48-linked ubiquitination;GO:0007094//mitotic spindle assembly checkpoint;GO:0000209//protein polyubiquitination;GO:0010390//histone monoubiquitination;GO:0033523//histone H2B ubiquitination;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0042296//ISG15 ligase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K06689//Ubiquitin mediated proteolysis;Shigellosis;Protein processing in endoplasmic reticulum
7325,0,3,0,7,27,0,0,0,0,133,1,0,UBE2E2;ubiquitin-conjugating enzyme E2E 2,-,GO:0070936//protein K48-linked ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0070534//protein K63-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0005524//ATP binding;GO:0042296//ISG15 ligase activity,K06689//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis;Shigellosis
7326,0,21,0,21,117,47,0,0,12,0,0,0,UBE2G1;ubiquitin-conjugating enzyme E2G 1,GO:0070062//extracellular vesicular exosome,GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity,K10575//Protein processing in endoplasmic reticulum;Parkinson's disease;Ubiquitin mediated proteolysis
7327,62,12,1,32,97,24,9,0,0,0,5,0,UBE2G2;ubiquitin-conjugating enzyme E2G 2,GO:0005829//cytosol;GO:0005783//endoplasmic reticulum,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0070936//protein K48-linked ubiquitination;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K04555//Ubiquitin mediated proteolysis;Parkinson's disease;Protein processing in endoplasmic reticulum
7328,0,41,1,55,104,13,0,0,6,0,0,0,UBE2H;ubiquitin-conjugating enzyme E2H,-,GO:0070936//protein K48-linked ubiquitination;GO:0070979//protein K11-linked ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K10576//Ubiquitin mediated proteolysis
7329,0,26,0,0,37,1,1,0,0,0,1,0,UBE2I;ubiquitin-conjugating enzyme E2I,GO:0001650//fibrillar center;GO:0045202//synapse;GO:0030425//dendrite;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0005634//nucleus;GO:0000795//synaptonemal complex,"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043687//post-translational protein modification;GO:0016032//viral process;GO:0006464//cellular protein modification process;GO:0010469//regulation of receptor activity;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:0016925//protein sumoylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0007059//chromosome segregation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0044267//cellular protein metabolic process",GO:0019899//enzyme binding;GO:0043425//bHLH transcription factor binding;GO:0019789//SUMO ligase activity;GO:0005524//ATP binding;GO:0071535//RING-like zinc finger domain binding;GO:0043398//HLH domain binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008134//transcription factor binding,K10577//RNA transport;Ubiquitin mediated proteolysis;NF-kappa B signaling pathway
733,0,0,0,0,0,1,0,0,14,0,0,0,"C8G;complement component 8, gamma polypeptide",GO:0005579//membrane attack complex;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,"GO:0030449//regulation of complement activation;GO:0006957//complement activation, alternative pathway;GO:0006958//complement activation, classical pathway;GO:0045087//innate immune response;GO:0019835//cytolysis",GO:0019841//retinol binding;GO:0001848//complement binding;GO:0032403//protein complex binding,K03999//Complement and coagulation cascades;Amoebiasis;Prion diseases;Systemic lupus erythematosus
7332,64,29,3,5,125,0,16,4,6,0,15,0,UBE2L3;ubiquitin-conjugating enzyme E2L 3,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000151//ubiquitin ligase complex,"GO:0008283//cell proliferation;GO:0071383//cellular response to steroid hormone stimulus;GO:0000209//protein polyubiquitination;GO:0006351//transcription, DNA-templated;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0016567//protein ubiquitination;GO:0006464//cellular protein modification process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0031398//positive regulation of protein ubiquitination;GO:0071385//cellular response to glucocorticoid stimulus",GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0003713//transcription coactivator activity;GO:0031625//ubiquitin protein ligase binding;GO:0016881//acid-amino acid ligase activity;GO:0044822//poly(A) RNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K04552//Parkinson's disease;Ubiquitin mediated proteolysis
7334,0,163,2,61,238,0,0,1,4,0,19,0,UBE2N;ubiquitin-conjugating enzyme E2N,GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0035370//UBC13-UEV1A complex;GO:0000151//ubiquitin ligase complex;GO:0031372//UBC13-MMS2 complex;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0033182//regulation of histone ubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006282//regulation of DNA repair;GO:0045087//innate immune response;GO:0006464//cellular protein modification process;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0016567//protein ubiquitination;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0045739//positive regulation of DNA repair;GO:0034166//toll-like receptor 10 signaling pathway;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0000729//DNA double-strand break processing;GO:0016574//histone ubiquitination;GO:0000724//double-strand break repair via homologous recombination;GO:0019221//cytokine-mediated signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0050852//T cell receptor signaling pathway;GO:0006508//proteolysis;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0031058//positive regulation of histone modification;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006301//postreplication repair",GO:0043130//ubiquitin binding;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K10580//Ubiquitin mediated proteolysis
7335,0,0,0,0,0,3,0,0,41,0,12,0,UBE2V1;ubiquitin-conjugating enzyme E2 variant 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000151//ubiquitin ligase complex;GO:0043234//protein complex;GO:0035370//UBC13-UEV1A complex;GO:0031371//ubiquitin conjugating enzyme complex;GO:0005737//cytoplasm,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045087//innate immune response;GO:0006282//regulation of DNA repair;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0000209//protein polyubiquitination;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0030154//cell differentiation;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0070534//protein K63-linked ubiquitination;GO:0050852//T cell receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0042275//error-free postreplication DNA repair",GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity;GO:0031624//ubiquitin conjugating enzyme binding,-
7336,0,40,0,24,94,15,0,0,18,0,0,0,UBE2V2;ubiquitin-conjugating enzyme E2 variant 2,GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031372//UBC13-MMS2 complex,GO:0016567//protein ubiquitination;GO:0000209//protein polyubiquitination;GO:0008283//cell proliferation;GO:0045739//positive regulation of DNA repair;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0051965//positive regulation of synapse assembly;GO:0010976//positive regulation of neuron projection development;GO:0000729//DNA double-strand break processing;GO:0043524//negative regulation of neuron apoptotic process;GO:0006282//regulation of DNA repair,GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity,-
7337,0,3,2,47,296,19,0,0,92,0,0,0,UBE3A;ubiquitin protein ligase E3A,GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0007420//brain development;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0006508//proteolysis;GO:0070936//protein K48-linked ubiquitination;GO:0001541//ovarian follicle development;GO:0060736//prostate gland growth;GO:0035037//sperm entry;GO:0016032//viral process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0030521//androgen receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051865//protein autoubiquitination,GO:0003713//transcription coactivator activity;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,K10587//Ubiquitin mediated proteolysis
734,0,0,0,27,38,14,0,0,52,0,41,0,OSGIN2;oxidative stress induced growth inhibitor family member 2,-,GO:0007126//meiotic nuclear division,-,-
7341,0,152,3,179,684,0,0,0,10,0,0,0,SUMO1;small ubiquitin-like modifier 1,GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0005730//nucleolus;GO:0016605//PML body;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0045202//synapse;GO:0030425//dendrite,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0090204//protein localization to nuclear pore;GO:0044267//cellular protein metabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0043392//negative regulation of DNA binding;GO:0043687//post-translational protein modification;GO:0006281//DNA repair;GO:0030578//PML body organization;GO:0060021//palate development;GO:0032880//regulation of protein localization;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0031334//positive regulation of protein complex assembly;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008134//transcription factor binding;GO:0019789//SUMO ligase activity,K12160//RNA transport
7342,18,25,0,8,60,0,2,0,15,0,12,1,UBP1;upstream binding protein 1 (LBP-1a),GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0006351//transcription, DNA-templated;GO:0019079//viral genome replication;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7343,0,1,2,43,98,0,0,1,44,275,0,32,"UBTF;upstream binding transcription factor, RNA polymerase I",GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0010467//gene expression;GO:0045943//positive regulation of transcription from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0000183//chromatin silencing at rDNA;GO:0006356//regulation of transcription from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter,GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
7345,0,0,0,7,0,0,1,0,52,0,0,0,UCHL1;ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase),GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0030424//axon;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0042755//eating behavior;GO:0002931//response to ischemia;GO:0008283//cell proliferation;GO:0043407//negative regulation of MAP kinase activity;GO:0050905//neuromuscular process;GO:0007628//adult walking behavior;GO:0019896//axon transport of mitochondrion;GO:0007412//axon target recognition;GO:0008219//cell death;GO:0048747//muscle fiber development;GO:0019233//sensory perception of pain;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0008242//omega peptidase activity;GO:0031694//alpha-2A adrenergic receptor binding;GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004197//cysteine-type endopeptidase activity,K05611//Parkinson's disease
7347,0,21,33,51,69,0,0,51,15,148,25,0,UCHL3;ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030163//protein catabolic process,GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0008233//peptidase activity;GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity,-
7348,0,0,0,0,0,0,4,0,33,0,0,0,UPK1B;uroplakin 1B,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0016324//apical plasma membrane,GO:0030855//epithelial cell differentiation,GO:0005198//structural molecule activity,K11447//Transcriptional misregulation in cancer;K06497//Lysosome
7349,0,0,0,0,0,0,0,0,1,0,0,0,UCN;urocortin,GO:0005576//extracellular region;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0043196//varicosity;GO:0043679//axon terminus,"GO:0007186//G-protein coupled receptor signaling pathway;GO:0035483//gastric emptying;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007218//neuropeptide signaling pathway;GO:0030157//pancreatic juice secretion;GO:0032099//negative regulation of appetite;GO:0051384//response to glucocorticoid;GO:0060455//negative regulation of gastric acid secretion;GO:0031175//neuron projection development;GO:0060547//negative regulation of necrotic cell death;GO:0043117//positive regulation of vascular permeability;GO:0048265//response to pain;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0090280//positive regulation of calcium ion import;GO:0045740//positive regulation of DNA replication;GO:0046888//negative regulation of hormone secretion;GO:2000252//negative regulation of feeding behavior;GO:0045776//negative regulation of blood pressure;GO:0051966//regulation of synaptic transmission, glutamatergic;GO:0045909//positive regulation of vasodilation;GO:0045792//negative regulation of cell size;GO:0045727//positive regulation of translation;GO:0006954//inflammatory response;GO:0051461//positive regulation of corticotropin secretion;GO:0032755//positive regulation of interleukin-6 production;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0008306//associative learning;GO:1901215//negative regulation of neuron death;GO:0032967//positive regulation of collagen biosynthetic process;GO:0031064//negative regulation of histone deacetylation;GO:0030307//positive regulation of cell growth;GO:0060452//positive regulation of cardiac muscle contraction;GO:0010629//negative regulation of gene expression;GO:0007565//female pregnancy;GO:0006979//response to oxidative stress;GO:2000987//positive regulation of behavioral fear response;GO:0009060//aerobic respiration;GO:0034199//activation of protein kinase A activity;GO:0032355//response to estradiol;GO:0042756//drinking behavior",GO:0051430//corticotropin-releasing hormone receptor 1 binding;GO:0005515//protein binding;GO:0005184//neuropeptide hormone activity;GO:0046811//histone deacetylase inhibitor activity,-
735,0,0,0,0,0,0,0,0,43,0,0,0,C9;complement component 9,GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005579//membrane attack complex;GO:0005737//cytoplasm,"GO:0006958//complement activation, classical pathway;GO:0030449//regulation of complement activation;GO:0019836//hemolysis by symbiont of host erythrocytes;GO:0006957//complement activation, alternative pathway;GO:0045087//innate immune response",-,K04000//Amoebiasis;Complement and coagulation cascades;Prion diseases;Systemic lupus erythematosus
7350,0,0,0,0,0,0,0,0,24,0,0,0,"UCP1;uncoupling protein 1 (mitochondrial, proton carrier)",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006839//mitochondrial transport;GO:0050873//brown fat cell differentiation;GO:0022904//respiratory electron transport chain;GO:0015992//proton transport;GO:0044237//cellular metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0044281//small molecule metabolic process,GO:0017077//oxidative phosphorylation uncoupler activity,K08769//PPAR signaling pathway;Huntington's disease
7351,0,16,0,0,12,0,17,0,8,0,0,0,"UCP2;uncoupling protein 2 (mitochondrial, proton carrier)",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0097421//liver regeneration;GO:0006839//mitochondrial transport;GO:0007565//female pregnancy;GO:0044281//small molecule metabolic process;GO:0010942//positive regulation of cell death;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0032869//cellular response to insulin stimulus;GO:0034198//cellular response to amino acid starvation;GO:0015992//proton transport;GO:0043066//negative regulation of apoptotic process;GO:0022904//respiratory electron transport chain;GO:0007568//aging;GO:0044237//cellular metabolic process;GO:0000303//response to superoxide;GO:0051881//regulation of mitochondrial membrane potential;GO:0006810//transport;GO:0001666//response to hypoxia;GO:0070542//response to fatty acid;GO:0071333//cellular response to glucose stimulus,-,-
7352,0,0,0,0,0,0,0,0,35,0,0,0,"UCP3;uncoupling protein 3 (mitochondrial, proton carrier)",GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0014823//response to activity;GO:0006631//fatty acid metabolic process;GO:0015992//proton transport;GO:0009409//response to cold;GO:0032868//response to insulin;GO:0044281//small molecule metabolic process;GO:0051384//response to glucocorticoid;GO:0007585//respiratory gaseous exchange;GO:0006839//mitochondrial transport;GO:0006629//lipid metabolic process;GO:0001666//response to hypoxia;GO:0007584//response to nutrient;GO:0000303//response to superoxide;GO:0044237//cellular metabolic process;GO:0032870//cellular response to hormone stimulus;GO:0022904//respiratory electron transport chain;GO:0007568//aging,GO:0017077//oxidative phosphorylation uncoupler activity;GO:0005515//protein binding;GO:0005215//transporter activity,-
7353,0,0,173,19,63,0,9,0,48,1,44,0,UFD1L;ubiquitin fusion degradation 1 like (yeast),GO:0005829//cytosol;GO:0005634//nucleus,GO:0001501//skeletal system development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0032403//protein complex binding;GO:0005102//receptor binding;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,K14016//Protein processing in endoplasmic reticulum
735301,0,0,0,0,0,0,0,28,0,0,0,0,SNHG9;small nucleolar RNA host gene 9 (non-protein coding),-,-,-,-
7355,0,0,0,0,0,12,0,0,40,0,16,0,"SLC35A2;solute carrier family 35 (UDP-galactose transporter), member A2",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005634//nucleus,GO:0006012//galactose metabolic process;GO:0072334//UDP-galactose transmembrane transport;GO:0055085//transmembrane transport;GO:0015785//UDP-galactose transport;GO:0015992//proton transport,GO:0005459//UDP-galactose transmembrane transporter activity;GO:0005515//protein binding;GO:0005351//sugar:proton symporter activity,-
7357,0,0,0,0,0,0,40,0,49,0,0,0,UGCG;UDP-glucose ceramide glucosyltransferase,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0006665//sphingolipid metabolic process;GO:0008544//epidermis development;GO:0006687//glycosphingolipid metabolic process;GO:0006679//glucosylceramide biosynthetic process;GO:0006688//glycosphingolipid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0008120//ceramide glucosyltransferase activity,K00720//Metabolic pathways;Sphingolipid metabolism
7358,0,43,1,63,308,0,6,0,0,0,0,0,UGDH;UDP-glucose 6-dehydrogenase,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006011//UDP-glucose metabolic process;GO:0055114//oxidation-reduction process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0001702//gastrulation with mouth forming second;GO:0052695//cellular glucuronidation;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006065//UDP-glucuronate biosynthetic process,GO:0009055//electron carrier activity;GO:0003979//UDP-glucose 6-dehydrogenase activity;GO:0051287//NAD binding,K00012//Pyrimidine metabolism;Mismatch repair;Homologous recombination;Base excision repair;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism;Ascorbate and aldarate metabolism;Purine metabolism;DNA replication;Metabolic pathways;Pentose and glucuronate interconversions
7360,2,96,1,37,147,47,0,0,26,0,15,0,UGP2;UDP-glucose pyrophosphorylase 2,GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0019255//glucose 1-phosphate metabolic process;GO:0006011//UDP-glucose metabolic process;GO:0005978//glycogen biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0052695//cellular glucuronidation;GO:0006006//glucose metabolic process;GO:0006065//UDP-glucuronate biosynthetic process;GO:0005975//carbohydrate metabolic process,GO:0005536//glucose binding;GO:0003983//UTP:glucose-1-phosphate uridylyltransferase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0032557//pyrimidine ribonucleotide binding,K00963//Glycolysis / Gluconeogenesis;Starch and sucrose metabolism;Butanoate metabolism;Galactose metabolism;Naphthalene degradation;Dioxin degradation;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Nucleotide excision repair;Microbial metabolism in diverse environments;One carbon pool by folate;Benzoate degradation;Fatty acid metabolism;Chloroalkane and chloroalkene degradation;Pentose and glucuronate interconversions;Metabolic pathways;Tyrosine metabolism;Pyruvate metabolism;Glyoxylate and dicarboxylate metabolism
7363,0,0,0,0,0,19,0,0,16,0,0,0,"UGT2B4;UDP glucuronosyltransferase 2 family, polypeptide B4",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006711//estrogen catabolic process;GO:0052695//cellular glucuronidation,GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding,K00699//Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Bile secretion;Retinol metabolism;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism
7364,0,0,0,0,0,0,0,0,17,0,0,0,"UGT2B7;UDP glucuronosyltransferase 2 family, polypeptide B7",GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006629//lipid metabolic process;GO:0008209//androgen metabolic process;GO:0052695//cellular glucuronidation,GO:0001972//retinoic acid binding;GO:0015020//glucuronosyltransferase activity,K00699//Bile secretion;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis;Pentose and glucuronate interconversions;Metabolic pathways;Drug metabolism - cytochrome P450;Starch and sucrose metabolism;Drug metabolism - other enzymes;Steroid hormone biosynthesis;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism
7365,89,0,0,0,0,14,22,0,88,0,0,0,"UGT2B10;UDP glucuronosyltransferase 2 family, polypeptide B10",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006629//lipid metabolic process,GO:0015020//glucuronosyltransferase activity,K00699//Starch and sucrose metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Bile secretion;Retinol metabolism;Drug metabolism - cytochrome P450;Metabolic pathways;Pentose and glucuronate interconversions
7366,0,0,0,0,0,0,0,0,21,0,0,0,"UGT2B15;UDP glucuronosyltransferase 2 family, polypeptide B15",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0052695//cellular glucuronidation;GO:0006805//xenobiotic metabolic process;GO:0008202//steroid metabolic process,GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding,K00699//Metabolism of xenobiotics by cytochrome P450;Other types of O-glycan biosynthesis;Retinol metabolism;Bile secretion;Pentose and glucuronate interconversions;Metabolic pathways;Drug metabolism - cytochrome P450;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism
7367,0,0,0,0,0,13,0,0,0,0,0,0,"UGT2B17;UDP glucuronosyltransferase 2 family, polypeptide B17",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0008202//steroid metabolic process;GO:0052695//cellular glucuronidation,GO:0015020//glucuronosyltransferase activity;GO:0001972//retinoic acid binding,K00699//Steroid hormone biosynthesis;Drug metabolism - other enzymes;Starch and sucrose metabolism;Ascorbate and aldarate metabolism;Porphyrin and chlorophyll metabolism;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Retinol metabolism;Bile secretion;Drug metabolism - cytochrome P450;Metabolic pathways;Pentose and glucuronate interconversions
7368,0,0,0,0,0,0,0,64,22,78,0,0,UGT8;UDP glycosyltransferase 8,GO:0016021//integral component of membrane,GO:0008088//axon cargo transport;GO:0002175//protein localization to paranode region of axon;GO:0007417//central nervous system development;GO:0007010//cytoskeleton organization;GO:0006682//galactosylceramide biosynthetic process;GO:0007422//peripheral nervous system development;GO:0048812//neuron projection morphogenesis;GO:0030913//paranodal junction assembly,"GO:0008489//UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity;GO:0003851//2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity",K04628//Sphingolipid metabolism;Metabolic pathways
7369,0,0,0,0,0,0,36,27,56,0,0,0,UMOD;uromodulin,GO:0072372//primary cilium;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0000922//spindle pole;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0045121//membrane raft;GO:0016324//apical plasma membrane;GO:0019898//extrinsic component of membrane;GO:0031225//anchored component of membrane;GO:0060170//ciliary membrane;GO:0031410//cytoplasmic vesicle,GO:1990266//neutrophil migration;GO:0072218//metanephric ascending thin limb development;GO:0072221//metanephric distal convoluted tubule development;GO:0010033//response to organic substance;GO:2000021//regulation of ion homeostasis;GO:0007159//leukocyte cell-cell adhesion;GO:0006968//cellular defense response;GO:0007588//excretion;GO:0072233//metanephric thick ascending limb development;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0008285//negative regulation of cell proliferation;GO:0048878//chemical homeostasis,GO:0019864//IgG binding;GO:0005509//calcium ion binding,-
7371,0,0,5,0,0,0,31,0,0,0,3,327,UCK2;uridine-cytidine kinase 2,GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle,GO:0016310//phosphorylation;GO:0044281//small molecule metabolic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0007631//feeding behavior;GO:0044206//UMP salvage;GO:0071453//cellular response to oxygen levels;GO:0044211//CTP salvage;GO:0048678//response to axon injury;GO:0043097//pyrimidine nucleoside salvage,GO:0004849//uridine kinase activity;GO:0019206//nucleoside kinase activity;GO:0005524//ATP binding,K00876//Pyrimidine metabolism;Aminobenzoate degradation;Drug metabolism - other enzymes;Metabolic pathways;Microbial metabolism in diverse environments;Pyruvate metabolism
7372,0,2,0,16,9,12,0,0,45,0,0,0,UMPS;uridine monophosphate synthetase,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0035690//cellular response to drug;GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0044205//'de novo' UMP biosynthetic process;GO:0044281//small molecule metabolic process;GO:0007595//lactation;GO:0006222//UMP biosynthetic process;GO:0007565//female pregnancy,GO:0004588//orotate phosphoribosyltransferase activity;GO:0004590//orotidine-5'-phosphate decarboxylase activity,K13421//Pyrimidine metabolism;Drug metabolism - other enzymes;Metabolic pathways
7373,127,0,0,0,1,31,0,49,92,0,22,0,"COL14A1;collagen, type XIV, alpha 1",GO:0005615//extracellular space;GO:0005614//interstitial matrix;GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0005581//collagen trimer;GO:0005596//collagen type XIV trimer;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0061050//regulation of cell growth involved in cardiac muscle cell development;GO:0030198//extracellular matrix organization;GO:0003229//ventricular cardiac muscle tissue development;GO:0022617//extracellular matrix disassembly;GO:0016337//single organismal cell-cell adhesion;GO:0048873//homeostasis of number of cells within a tissue;GO:0030574//collagen catabolic process;GO:0030199//collagen fibril organization,"GO:0005201//extracellular matrix structural constituent;GO:0044822//poly(A) RNA binding;GO:0030674//protein binding, bridging;GO:0005518//collagen binding",K08133//Protein digestion and absorption
7374,0,1,0,8,18,0,0,0,42,0,0,0,UNG;uracil-DNA glycosylase,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0006284//base-excision repair;GO:0016032//viral process;GO:0016447//somatic recombination of immunoglobulin gene segments;GO:0043066//negative regulation of apoptotic process;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006281//DNA repair,GO:0005515//protein binding;GO:0004844//uracil DNA N-glycosylase activity,K03648//Primary immunodeficiency;Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Base excision repair;Selenocompound metabolism
7375,0,0,0,6,41,57,0,64,20,66,11,0,USP4;ubiquitin specific peptidase 4 (proto-oncogene),GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0016579//protein deubiquitination;GO:0031397//negative regulation of protein ubiquitination;GO:0031647//regulation of protein stability;GO:0034394//protein localization to cell surface;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0031685//adenosine receptor binding;GO:0004221//ubiquitin thiolesterase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0004843//ubiquitin-specific protease activity,-
7376,13,0,0,1,10,0,0,148,7,0,0,0,"NR1H2;nuclear receptor subfamily 1, group H, member 2",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0032270//positive regulation of cellular protein metabolic process;GO:0032376//positive regulation of cholesterol transport;GO:0048384//retinoic acid receptor signaling pathway;GO:0044255//cellular lipid metabolic process;GO:0045723//positive regulation of fatty acid biosynthetic process;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0051006//positive regulation of lipoprotein lipase activity;GO:2000188//regulation of cholesterol homeostasis;GO:0010887//negative regulation of cholesterol storage;GO:0010875//positive regulation of cholesterol efflux;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032369//negative regulation of lipid transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0048550//negative regulation of pinocytosis;GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0010745//negative regulation of macrophage derived foam cell differentiation",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0046965//retinoid X receptor binding;GO:0001133//sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0051117//ATPase binding;GO:0003677//DNA binding;GO:0034191//apolipoprotein A-I receptor binding,-
7378,0,0,0,10,0,15,0,33,0,112,0,0,UPP1;uridine phosphorylase 1,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0046108//uridine metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0044206//UMP salvage;GO:0046135//pyrimidine nucleoside catabolic process;GO:0042149//cellular response to glucose starvation;GO:0006139//nucleobase-containing compound metabolic process;GO:0009166//nucleotide catabolic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0004850//uridine phosphorylase activity,K00757//Pyrimidine metabolism;Drug metabolism - other enzymes;Metabolic pathways;ABC transporters
7379,0,0,0,0,12,0,0,1,18,0,0,0,UPK2;uroplakin 2,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0016324//apical plasma membrane;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007275//multicellular organismal development;GO:0061024//membrane organization;GO:0030855//epithelial cell differentiation,-,-
738,0,1,0,4,7,0,0,1,5,0,45,0,VPS51;vacuolar protein sorting 51 homolog (S. cerevisiae),GO:0000938//GARP complex;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,"GO:0006914//autophagy;GO:0015031//protein transport;GO:0006869//lipid transport;GO:0042147//retrograde transport, endosome to Golgi",GO:0005515//protein binding,-
7380,0,0,0,3,0,0,0,0,7,0,1,0,UPK3A;uroplakin 3A,GO:0005789//endoplasmic reticulum membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0006833//water transport;GO:0060157//urinary bladder development;GO:0001822//kidney development;GO:0055078//sodium ion homeostasis;GO:0055075//potassium ion homeostasis;GO:0030855//epithelial cell differentiation;GO:0000902//cell morphogenesis;GO:0015840//urea transport,-,-
7381,0,9,39,29,131,0,21,0,51,0,10,0,UQCRB;ubiquinol-cytochrome c reductase binding protein,GO:0005746//mitochondrial respiratory chain;GO:0005750//mitochondrial respiratory chain complex III;GO:0005743//mitochondrial inner membrane,"GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0022904//respiratory electron transport chain;GO:0055114//oxidation-reduction process;GO:0006119//oxidative phosphorylation;GO:0044237//cellular metabolic process;GO:0009060//aerobic respiration;GO:0044281//small molecule metabolic process",-,K00417//Cardiac muscle contraction;Metabolic pathways;Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease
7384,83,1,1,2,21,17,0,0,60,0,0,0,UQCRC1;ubiquinol-cytochrome c reductase core protein I,GO:0005750//mitochondrial respiratory chain complex III;GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respiratory chain,"GO:0009060//aerobic respiration;GO:0014823//response to activity;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0055114//oxidation-reduction process;GO:0006119//oxidative phosphorylation;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0043279//response to alkaloid",GO:0032403//protein complex binding;GO:0008121//ubiquinol-cytochrome-c reductase activity;GO:0046872//metal ion binding,K00414//Cardiac muscle contraction;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
7385,11,1,3,9,90,0,34,0,28,1,10,534,UQCRC2;ubiquinol-cytochrome c reductase core protein II,GO:0005739//mitochondrion;GO:0005750//mitochondrial respiratory chain complex III;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane,GO:0009060//aerobic respiration;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0006508//proteolysis;GO:0022904//respiratory electron transport chain;GO:0006119//oxidative phosphorylation,GO:0032403//protein complex binding;GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K00415//Cardiac muscle contraction;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways
7386,0,51,0,45,120,0,0,0,0,0,0,0,"UQCRFS1;ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005750//mitochondrial respiratory chain complex III,GO:0009725//response to hormone;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0046677//response to antibiotic;GO:0022904//respiratory electron transport chain;GO:1902600//hydrogen ion transmembrane transport;GO:0042493//response to drug,"GO:0051537//2 iron, 2 sulfur cluster binding;GO:0032403//protein complex binding;GO:0046872//metal ion binding;GO:0008121//ubiquinol-cytochrome-c reductase activity",K00411//Huntington's disease;Parkinson's disease;Cardiac muscle contraction;Two-component system;Metabolic pathways;Oxidative phosphorylation;Alzheimer's disease;Nitrogen metabolism
7388,0,80,1,43,110,0,0,61,5,0,0,0,UQCRH;ubiquinol-cytochrome c reductase hinge protein,GO:0005746//mitochondrial respiratory chain;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005750//mitochondrial respiratory chain complex III,"GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:0006122//mitochondrial electron transport, ubiquinol to cytochrome c;GO:0055114//oxidation-reduction process;GO:0006119//oxidative phosphorylation;GO:0051291//protein heterooligomerization;GO:0009060//aerobic respiration",GO:0032403//protein complex binding;GO:0008121//ubiquinol-cytochrome-c reductase activity,K00416//Cardiac muscle contraction;Metabolic pathways;Oxidative phosphorylation;Huntington's disease;Parkinson's disease;Alzheimer's disease
7389,0,0,1,7,17,0,13,0,0,0,6,0,UROD;uroporphyrinogen decarboxylase,GO:0005829//cytosol,GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006778//porphyrin-containing compound metabolic process;GO:0006783//heme biosynthetic process,GO:0004853//uroporphyrinogen decarboxylase activity,K01599//Metabolic pathways;Porphyrin and chlorophyll metabolism;Biosynthesis of secondary metabolites
7390,0,2,0,25,17,0,0,0,0,0,0,0,UROS;uroporphyrinogen III synthase,GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0046677//response to antibiotic;GO:0044281//small molecule metabolic process;GO:0006782//protoporphyrinogen IX biosynthetic process;GO:0006780//uroporphyrinogen III biosynthetic process;GO:0071243//cellular response to arsenic-containing substance;GO:0006778//porphyrin-containing compound metabolic process;GO:0071418//cellular response to amine stimulus;GO:0006783//heme biosynthetic process,GO:0048037//cofactor binding;GO:0004852//uroporphyrinogen-III synthase activity,K01719//Metabolic pathways;Propanoate metabolism;Pyruvate metabolism;Methane metabolism;Biosynthesis of secondary metabolites;Taurine and hypotaurine metabolism;Microbial metabolism in diverse environments;Porphyrin and chlorophyll metabolism
7391,0,0,1,0,14,12,0,0,41,20,0,0,USF1;upstream transcription factor 1,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0032869//cellular response to insulin stimulus;GO:0006366//transcription from RNA polymerase II promoter;GO:0001666//response to hypoxia;GO:0009411//response to UV;GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0019086//late viral transcription;GO:0042593//glucose homeostasis;GO:0055088//lipid homeostasis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051918//negative regulation of fibrinolysis;GO:0006006//glucose metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003690//double-stranded DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0043425//bHLH transcription factor binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0019901//protein kinase binding;GO:0043565//sequence-specific DNA binding,-
7392,0,0,0,1,43,1,0,0,27,0,0,0,"USF2;upstream transcription factor 2, c-fos interacting",GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0000430//regulation of transcription from RNA polymerase II promoter by glucose;GO:0006351//transcription, DNA-templated;GO:0000432//positive regulation of transcription from RNA polymerase II promoter by glucose;GO:0019086//late viral transcription;GO:0007595//lactation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0055088//lipid homeostasis",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0043425//bHLH transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003690//double-stranded DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity,-
7398,0,0,20,48,23,0,25,0,65,0,0,0,USP1;ubiquitin specific peptidase 1,GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0009411//response to UV;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001501//skeletal system development;GO:0006282//regulation of DNA repair;GO:0016579//protein deubiquitination;GO:0035520//monoubiquitinated protein deubiquitination;GO:0006281//DNA repair,GO:0004843//ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0004221//ubiquitin thiolesterase activity,K11832//Fanconi anemia pathway
7399,95,0,0,0,1,84,59,32,175,4,0,40,"USH2A;Usher syndrome 2A (autosomal recessive, mild)",GO:0060171//stereocilium membrane;GO:0032421//stereocilium bundle;GO:0005604//basement membrane;GO:0016021//integral component of membrane;GO:0002142//stereocilia ankle link complex;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane,GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0048496//maintenance of organ identity;GO:0007605//sensory perception of sound;GO:0035315//hair cell differentiation;GO:0050953//sensory perception of light stimulus;GO:0060113//inner ear receptor cell differentiation;GO:0045494//photoreceptor cell maintenance,GO:0005518//collagen binding;GO:0005515//protein binding;GO:0017022//myosin binding,K06240//Amoebiasis;Small cell lung cancer;Focal adhesion;ECM-receptor interaction;Toxoplasmosis;Pathways in cancer
740,0,19,0,16,50,0,0,47,13,0,6,0,MRPL49;mitochondrial ribosomal protein L49,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
7401,0,0,0,0,0,0,0,0,2,0,0,0,CLRN1;clarin 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030027//lamellipodium;GO:0005902//microvillus,GO:0050896//response to stimulus;GO:0007601//visual perception;GO:0007605//sensory perception of sound;GO:0050957//equilibrioception;GO:0007015//actin filament organization;GO:0060088//auditory receptor cell stereocilium organization;GO:0048870//cell motility;GO:0050953//sensory perception of light stimulus;GO:0010592//positive regulation of lamellipodium assembly;GO:0045494//photoreceptor cell maintenance,-,-
7402,0,95,4,152,588,55,42,43,126,0,13,286,UTRN;utrophin,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0016010//dystrophin-associated glycoprotein complex;GO:0031594//neuromuscular junction;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0030016//myofibril;GO:0031527//filopodium membrane;GO:0016020//membrane;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0045211//postsynaptic membrane;GO:0070938//contractile ring;GO:0042383//sarcolemma,GO:0090287//regulation of cellular response to growth factor stimulus;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0001954//positive regulation of cell-matrix adhesion;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0042692//muscle cell differentiation;GO:0045666//positive regulation of neuron differentiation;GO:0010976//positive regulation of neuron projection development;GO:0048812//neuron projection morphogenesis;GO:0007568//aging,GO:0017166//vinculin binding;GO:0003779//actin binding;GO:0019901//protein kinase binding;GO:0030165//PDZ domain binding;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0008270//zinc ion binding,K10366//Dilated cardiomyopathy;Viral myocarditis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
7403,78,0,0,13,12,4,11,0,50,0,0,0,KDM6A;lysine (K)-specific demethylase 6A,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,GO:0060070//canonical Wnt signaling pathway;GO:0051568//histone H3-K4 methylation;GO:0048570//notochord morphogenesis;GO:0035264//multicellular organism growth;GO:0010468//regulation of gene expression;GO:0055114//oxidation-reduction process;GO:0032525//somite rostral/caudal axis specification;GO:0001701//in utero embryonic development;GO:0003007//heart morphogenesis;GO:0071557//histone H3-K27 demethylation;GO:0048333//mesodermal cell differentiation;GO:0003016//respiratory system process;GO:0001843//neural tube closure,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0042802//identical protein binding;GO:0071558//histone demethylase activity (H3-K27 specific);GO:0051213//dioxygenase activity,K11447//Transcriptional misregulation in cancer
7404,0,82,0,22,61,0,0,0,0,0,76,0,"UTY;ubiquitously transcribed tetratricopeptide repeat containing, Y-linked",GO:0005634//nucleus,GO:0055114//oxidation-reduction process;GO:0010468//regulation of gene expression;GO:0071557//histone H3-K27 demethylation,GO:0071558//histone demethylase activity (H3-K27 specific);GO:0046872//metal ion binding;GO:0051213//dioxygenase activity,K11447//Transcriptional misregulation in cancer
7405,15,1,1,8,34,5,35,78,36,0,10,0,UVRAG;UV radiation resistance associated,GO:0005770//late endosome;GO:0045335//phagocytic vesicle;GO:0005769//early endosome;GO:0043234//protein complex;GO:0005764//lysosome;GO:0005737//cytoplasm,GO:0010508//positive regulation of autophagy;GO:0006281//DNA repair;GO:0046718//viral entry into host cell;GO:0035493//SNARE complex assembly,GO:0017124//SH3 domain binding;GO:0000149//SNARE binding;GO:0005515//protein binding,-
7408,0,29,1,26,30,11,32,0,26,172,0,0,VASP;vasodilator-stimulated phosphoprotein,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0031527//filopodium membrane;GO:0005923//tight junction;GO:0005925//focal adhesion;GO:0031258//lamellipodium membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol,GO:0051289//protein homotetramerization;GO:0030838//positive regulation of actin filament polymerization;GO:0008154//actin polymerization or depolymerization;GO:0001843//neural tube closure;GO:0007411//axon guidance;GO:0050852//T cell receptor signaling pathway;GO:0034329//cell junction assembly,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0003779//actin binding;GO:0005522//profilin binding,K06274//Fc gamma R-mediated phagocytosis;Focal adhesion;Leukocyte transendothelial migration
7409,0,0,0,0,0,0,0,42,35,0,5,0,VAV1;vav 1 guanine nucleotide exchange factor,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005911//cell-cell junction,"GO:0030593//neutrophil chemotaxis;GO:0032855//positive regulation of Rac GTPase activity;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042110//T cell activation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0007264//small GTPase mediated signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0072593//reactive oxygen species metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007596//blood coagulation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0032314//regulation of Rac GTPase activity;GO:0030168//platelet activation;GO:0007229//integrin-mediated signaling pathway;GO:0045785//positive regulation of cell adhesion",GO:0005085//guanyl-nucleotide exchange factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K05730//Focal adhesion;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;B cell receptor signaling pathway;Chemokine signaling pathway;Fc epsilon RI signaling pathway
741,0,0,0,0,13,24,0,0,12,97,0,0,"ZNHIT2;zinc finger, HIT-type containing 2",-,-,GO:0046872//metal ion binding,-
7410,0,0,0,0,8,12,26,0,37,0,57,0,VAV2;vav 2 guanine nucleotide exchange factor,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0016477//cell migration;GO:0032321//positive regulation of Rho GTPase activity;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0030032//lamellipodium assembly;GO:0007596//blood coagulation;GO:0010468//regulation of gene expression;GO:0001525//angiogenesis;GO:0030193//regulation of blood coagulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0007411//axon guidance,GO:0046872//metal ion binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005154//epidermal growth factor receptor binding;GO:0005085//guanyl-nucleotide exchange factor activity,K05730//Fc gamma R-mediated phagocytosis;B cell receptor signaling pathway;Leukocyte transendothelial migration;Chemokine signaling pathway;Fc epsilon RI signaling pathway;Focal adhesion;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Regulation of actin cytoskeleton
7411,41,40,1,16,19,1,0,0,19,0,0,0,VBP1;von Hippel-Lindau binding protein 1,GO:0043231//intracellular membrane-bounded organelle;GO:0016272//prefoldin complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051084//'de novo' posttranslational protein folding;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process,GO:0051082//unfolded protein binding;GO:0005515//protein binding,-
7412,0,0,0,0,0,20,0,0,17,0,0,0,VCAM1;vascular cell adhesion molecule 1,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0030175//filopodium;GO:0009897//external side of plasma membrane;GO:0071065//alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0005902//microvillus;GO:0005615//extracellular space;GO:0042383//sarcolemma;GO:0002102//podosome,GO:0019221//cytokine-mediated signaling pathway;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007155//cell adhesion;GO:0071333//cellular response to glucose stimulus;GO:0001666//response to hypoxia;GO:0007160//cell-matrix adhesion;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0071356//cellular response to tumor necrosis factor;GO:0035094//response to nicotine;GO:0050776//regulation of immune response;GO:0002526//acute inflammatory response;GO:0042102//positive regulation of T cell proliferation;GO:0010043//response to zinc ion;GO:0030183//B cell differentiation;GO:0016032//viral process;GO:0007568//aging;GO:0022614//membrane to membrane docking;GO:0045471//response to ethanol;GO:0002544//chronic inflammatory response;GO:0060710//chorio-allantoic fusion;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0032496//response to lipopolysaccharide;GO:0007159//leukocyte cell-cell adhesion;GO:0060326//cell chemotaxis;GO:0009308//amine metabolic process;GO:0007507//heart development;GO:0010212//response to ionizing radiation;GO:0030198//extracellular matrix organization;GO:0050901//leukocyte tethering or rolling,GO:0005178//integrin binding;GO:0008131//primary amine oxidase activity;GO:0050839//cell adhesion molecule binding,K06527//Cell adhesion molecules (CAMs);Malaria;HTLV-I infection;NF-kappa B signaling pathway;African trypanosomiasis;Leukocyte transendothelial migration
7414,0,0,0,3,12,0,76,0,23,0,15,0,VCL;vinculin,GO:0043234//protein complex;GO:0005913//cell-cell adherens junction;GO:0005856//cytoskeleton;GO:0005911//cell-cell junction;GO:0030055//cell-substrate junction;GO:0031982//vesicle;GO:0043034//costamere;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005916//fascia adherens;GO:0005912//adherens junction;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion,GO:0007160//cell-matrix adhesion;GO:0002009//morphogenesis of an epithelium;GO:0034394//protein localization to cell surface;GO:0007596//blood coagulation;GO:0034333//adherens junction assembly;GO:0002576//platelet degranulation;GO:0043297//apical junction assembly;GO:0030032//lamellipodium assembly;GO:0030336//negative regulation of cell migration;GO:0007155//cell adhesion;GO:0006928//cellular component movement;GO:0006936//muscle contraction;GO:0070527//platelet aggregation;GO:0090136//epithelial cell-cell adhesion;GO:0030168//platelet activation,GO:0045294//alpha-catenin binding;GO:0008013//beta-catenin binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0045296//cadherin binding;GO:0002162//dystroglycan binding,K05700//Adherens junction;Shigellosis;Leukocyte transendothelial migration;Focal adhesion;Amoebiasis;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton
7415,0,2,5,17,122,1,0,96,45,143,4,0,VCP;valosin containing protein,GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0035861//site of double-strand break;GO:0070062//extracellular vesicular exosome,"GO:0016567//protein ubiquitination;GO:0019985//translesion synthesis;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0030970//retrograde protein transport, ER to cytosol;GO:0031334//positive regulation of protein complex assembly;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0051260//protein homooligomerization;GO:1903006//positive regulation of protein K63-linked deubiquitination;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070842//aggresome assembly;GO:0045184//establishment of protein localization;GO:1903007//positive regulation of Lys63-specific deubiquitinase activity;GO:0006302//double-strand break repair;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0006974//cellular response to DNA damage stimulus;GO:0042981//regulation of apoptotic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:1990381//ubiquitin-specific protease binding;GO:0005102//receptor binding;GO:0043531//ADP binding;GO:0031593//polyubiquitin binding;GO:0042802//identical protein binding;GO:0016887//ATPase activity;GO:0019904//protein domain specific binding;GO:0008289//lipid binding;GO:0035800//deubiquitinase activator activity;GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0019903//protein phosphatase binding,K13525//Legionellosis;Protein processing in endoplasmic reticulum
7416,0,85,2,53,127,13,0,358,46,0,75,0,VDAC1;voltage-dependent anion channel 1,GO:0005741//mitochondrial outer membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005743//mitochondrial inner membrane;GO:0046930//pore complex;GO:0042645//mitochondrial nucleoid;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0016032//viral process;GO:0001662//behavioral fear response;GO:0006915//apoptotic process;GO:0007270//neuron-neuron synaptic transmission;GO:0006820//anion transport;GO:0007612//learning;GO:0044070//regulation of anion transport;GO:0030855//epithelial cell differentiation;GO:0055085//transmembrane transport,GO:0008308//voltage-gated anion channel activity;GO:0015288//porin activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,K05862//Influenza A;Calcium signaling pathway;HTLV-I infection;Huntington's disease;Parkinson's disease
7417,0,3,1,24,32,0,0,0,45,0,0,0,VDAC2;voltage-dependent anion channel 2,GO:0005739//mitochondrion;GO:0046930//pore complex;GO:0042645//mitochondrial nucleoid;GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane;GO:0005634//nucleus,GO:0032272//negative regulation of protein polymerization;GO:0044070//regulation of anion transport;GO:0055085//transmembrane transport;GO:0006820//anion transport;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway,GO:0015288//porin activity;GO:0008308//voltage-gated anion channel activity;GO:0000166//nucleotide binding;GO:0005515//protein binding,K15040//Huntington's disease;HTLV-I infection;Parkinson's disease;Calcium signaling pathway
7419,0,0,0,6,31,0,0,0,13,0,0,0,VDAC3;voltage-dependent anion channel 3,GO:0070062//extracellular vesicular exosome;GO:0005741//mitochondrial outer membrane;GO:0005739//mitochondrion;GO:0046930//pore complex;GO:0005634//nucleus,GO:0055085//transmembrane transport;GO:0044070//regulation of anion transport;GO:0015853//adenine transport;GO:0006820//anion transport,GO:0008308//voltage-gated anion channel activity;GO:0015288//porin activity;GO:0000166//nucleotide binding,K15041//Calcium signaling pathway;Huntington's disease;HTLV-I infection;Parkinson's disease
7421,0,12,0,0,0,0,23,0,0,57,10,0,"VDR;vitamin D (1,25- dihydroxyvitamin D3) receptor",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050892//intestinal absorption;GO:0009887//organ morphogenesis;GO:0010467//gene expression;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0006816//calcium ion transport;GO:0060058//positive regulation of apoptotic process involved in mammary gland involution;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0045618//positive regulation of keratinocyte differentiation;GO:0006874//cellular calcium ion homeostasis;GO:0010839//negative regulation of keratinocyte proliferation;GO:0038183//bile acid signaling pathway;GO:0060558//regulation of calcidiol 1-monooxygenase activity;GO:0046697//decidualization;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0000902//cell morphogenesis;GO:0001501//skeletal system development;GO:0007165//signal transduction;GO:0070561//vitamin D receptor signaling pathway;GO:0007595//lactation;GO:0060745//mammary gland branching involved in pregnancy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0070644//vitamin D response element binding;GO:0043565//sequence-specific DNA binding;GO:0038186//lithocholic acid receptor activity;GO:0003677//DNA binding;GO:1902098//calcitriol binding;GO:0008434//calcitriol receptor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:1902121//lithocholic acid binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0046965//retinoid X receptor binding,K08539//Endocrine and other factor-regulated calcium reabsorption;Tuberculosis;Mineral absorption
7422,0,1,0,0,21,0,0,63,0,0,32,0,VEGFA;vascular endothelial growth factor A,GO:0031093//platelet alpha granule lumen;GO:0005615//extracellular space;GO:0030141//secretory granule;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm;GO:0009986//cell surface;GO:0016020//membrane;GO:0005576//extracellular region,GO:0002092//positive regulation of receptor internalization;GO:1902533//positive regulation of intracellular signal transduction;GO:0001541//ovarian follicle development;GO:0031077//post-embryonic camera-type eye development;GO:0031954//positive regulation of protein autophosphorylation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0071679//commissural neuron axon guidance;GO:0001666//response to hypoxia;GO:0030324//lung development;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0003169//coronary vein morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0038190//VEGF-activated neuropilin signaling pathway;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007498//mesoderm development;GO:0030335//positive regulation of cell migration;GO:0048593//camera-type eye morphogenesis;GO:0051894//positive regulation of focal adhesion assembly;GO:1902966//positive regulation of protein localization to early endosome;GO:0071456//cellular response to hypoxia;GO:0045766//positive regulation of angiogenesis;GO:0040007//growth;GO:0001934//positive regulation of protein phosphorylation;GO:0030855//epithelial cell differentiation;GO:0002576//platelet degranulation;GO:0060948//cardiac vascular smooth muscle cell development;GO:0007596//blood coagulation;GO:0030224//monocyte differentiation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007595//lactation;GO:0051781//positive regulation of cell division;GO:0060982//coronary artery morphogenesis;GO:1900745//positive regulation of p38MAPK cascade;GO:0038033//positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway;GO:0060319//primitive erythrocyte differentiation;GO:0051272//positive regulation of cellular component movement;GO:0032147//activation of protein kinase activity;GO:0050679//positive regulation of epithelial cell proliferation;GO:1901727//positive regulation of histone deacetylase activity;GO:0030225//macrophage differentiation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0060749//mammary gland alveolus development;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0002575//basophil chemotaxis;GO:0001525//angiogenesis;GO:0071542//dopaminergic neuron differentiation;GO:0002687//positive regulation of leukocyte migration;GO:0050918//positive chemotaxis;GO:0050927//positive regulation of positive chemotaxis;GO:0043129//surfactant homeostasis;GO:0048469//cell maturation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0007399//nervous system development;GO:0035148//tube formation;GO:1902336//positive regulation of retinal ganglion cell axon guidance;GO:0090037//positive regulation of protein kinase C signaling;GO:0038084//vascular endothelial growth factor signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0061419//positive regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0001938//positive regulation of endothelial cell proliferation;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0001570//vasculogenesis;GO:0031334//positive regulation of protein complex assembly;GO:0043406//positive regulation of MAP kinase activity;GO:0001701//in utero embryonic development;GO:0043117//positive regulation of vascular permeability;GO:0032793//positive regulation of CREB transcription factor activity;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060754//positive regulation of mast cell chemotaxis;GO:0035767//endothelial cell chemotaxis;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0048844//artery morphogenesis;GO:0038091//positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway;GO:0030168//platelet activation;GO:0001569//patterning of blood vessels;GO:0042462//eye photoreceptor cell development;GO:0003007//heart morphogenesis;GO:0003151//outflow tract morphogenesis;GO:1900086//positive regulation of peptidyl-tyrosine autophosphorylation;GO:0008360//regulation of cell shape;GO:0002052//positive regulation of neuroblast proliferation;GO:0010628//positive regulation of gene expression;GO:0043066//negative regulation of apoptotic process;GO:0050930//induction of positive chemotaxis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0048739//cardiac muscle fiber development;GO:0001822//kidney development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008284//positive regulation of cell proliferation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005161//platelet-derived growth factor receptor binding;GO:0048018//receptor agonist activity;GO:0042802//identical protein binding;GO:0005172//vascular endothelial growth factor receptor binding;GO:0008201//heparin binding;GO:0005515//protein binding;GO:0050840//extracellular matrix binding;GO:0038191//neuropilin binding;GO:0043183//vascular endothelial growth factor receptor 1 binding;GO:0008083//growth factor activity;GO:0001968//fibronectin binding;GO:0046982//protein heterodimerization activity;GO:0042056//chemoattractant activity;GO:0042803//protein homodimerization activity;GO:0005125//cytokine activity;GO:0043184//vascular endothelial growth factor receptor 2 binding,K05448//Cytokine-cytokine receptor interaction;mTOR signaling pathway;Bladder cancer;Focal adhesion;VEGF signaling pathway;Renal cell carcinoma;Pathways in cancer;Rheumatoid arthritis;Pancreatic cancer
7423,0,0,0,0,0,0,1,0,0,0,0,0,VEGFB;vascular endothelial growth factor B,GO:0005615//extracellular space;GO:0031093//platelet alpha granule lumen;GO:0016020//membrane;GO:0005576//extracellular region,GO:0043066//negative regulation of apoptotic process;GO:0001938//positive regulation of endothelial cell proliferation;GO:0050930//induction of positive chemotaxis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0035470//positive regulation of vascular wound healing;GO:0001525//angiogenesis;GO:0060048//cardiac muscle contraction;GO:0043117//positive regulation of vascular permeability;GO:0010629//negative regulation of gene expression;GO:0051897//positive regulation of protein kinase B signaling;GO:0050918//positive chemotaxis;GO:0042493//response to drug;GO:0060754//positive regulation of mast cell chemotaxis;GO:0006493//protein O-linked glycosylation;GO:0002576//platelet degranulation;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007596//blood coagulation;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0030168//platelet activation;GO:0060976//coronary vasculature development;GO:0051781//positive regulation of cell division;GO:0043524//negative regulation of neuron apoptotic process,GO:0043183//vascular endothelial growth factor receptor 1 binding;GO:0008083//growth factor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008201//heparin binding;GO:0042056//chemoattractant activity,K05448//Pathways in cancer;Pancreatic cancer;Rheumatoid arthritis;Bladder cancer;Renal cell carcinoma;VEGF signaling pathway;Focal adhesion;mTOR signaling pathway;Cytokine-cytokine receptor interaction
7424,0,0,0,0,0,25,13,0,0,0,0,0,VEGFC;vascular endothelial growth factor C,GO:0005615//extracellular space;GO:0016020//membrane;GO:0031093//platelet alpha granule lumen;GO:0005576//extracellular region,GO:0001954//positive regulation of cell-matrix adhesion;GO:0016331//morphogenesis of embryonic epithelium;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0050930//induction of positive chemotaxis;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0002052//positive regulation of neuroblast proliferation;GO:0006929//substrate-dependent cell migration;GO:0050679//positive regulation of epithelial cell proliferation;GO:0009887//organ morphogenesis;GO:0045766//positive regulation of angiogenesis;GO:0050918//positive chemotaxis;GO:0008284//positive regulation of cell proliferation;GO:0042493//response to drug;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:1901492//positive regulation of lymphangiogenesis;GO:0001525//angiogenesis;GO:0007596//blood coagulation;GO:0031954//positive regulation of protein autophosphorylation;GO:0002576//platelet degranulation;GO:0043536//positive regulation of blood vessel endothelial cell migration;GO:0060754//positive regulation of mast cell chemotaxis;GO:0050714//positive regulation of protein secretion;GO:0051781//positive regulation of cell division;GO:0045776//negative regulation of blood pressure;GO:0007165//signal transduction;GO:0030168//platelet activation,GO:0043185//vascular endothelial growth factor receptor 3 binding;GO:0008083//growth factor activity;GO:0042056//chemoattractant activity;GO:0005515//protein binding,K05449//Focal adhesion;Renal cell carcinoma;Bladder cancer;Pancreatic cancer;Cytokine-cytokine receptor interaction;mTOR signaling pathway;Pathways in cancer
7425,91,0,0,0,0,0,0,0,24,77,6,0,VGF;VGF nerve growth factor inducible,GO:0031410//cytoplasmic vesicle;GO:0030133//transport vesicle;GO:0005615//extracellular space,GO:0019953//sexual reproduction;GO:0042742//defense response to bacterium;GO:0002021//response to dietary excess;GO:0009409//response to cold;GO:0001541//ovarian follicle development;GO:0006091//generation of precursor metabolites and energy;GO:0032868//response to insulin;GO:0042593//glucose homeostasis;GO:0051591//response to cAMP;GO:0030073//insulin secretion,GO:0005184//neuropeptide hormone activity;GO:0008083//growth factor activity,-
7428,0,0,1,19,34,0,22,0,3,0,0,0,"VHL;von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase",GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005634//nucleus,"GO:0016567//protein ubiquitination;GO:0050821//protein stabilization;GO:0006508//proteolysis;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000902//cell morphogenesis;GO:0045597//positive regulation of cell differentiation;GO:0071456//cellular response to hypoxia;GO:0006355//regulation of transcription, DNA-templated;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0045893//positive regulation of transcription, DNA-templated;GO:0061428//negative regulation of transcription from RNA polymerase II promoter in response to hypoxia",GO:0019899//enzyme binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0061630//ubiquitin protein ligase activity;GO:0008134//transcription factor binding,K03871//Pathways in cancer;Renal cell carcinoma;Ubiquitin mediated proteolysis
7429,0,0,0,0,0,7,0,18,51,103,12,12,VIL1;villin 1,GO:0001726//ruffle;GO:0030175//filopodium;GO:0032433//filopodium tip;GO:0070062//extracellular vesicular exosome;GO:0030027//lamellipodium;GO:0005902//microvillus;GO:0032432//actin filament bundle;GO:0005737//cytoplasm,GO:0030855//epithelial cell differentiation;GO:0030042//actin filament depolymerization;GO:0010634//positive regulation of epithelial cell migration;GO:0051014//actin filament severing;GO:0061041//regulation of wound healing;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0009617//response to bacterium;GO:0032233//positive regulation of actin filament bundle assembly;GO:0030335//positive regulation of cell migration;GO:0008360//regulation of cell shape;GO:0060327//cytoplasmic actin-based contraction involved in cell motility;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0030041//actin filament polymerization;GO:0051125//regulation of actin nucleation;GO:0051693//actin filament capping;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006461//protein complex assembly;GO:2000392//regulation of lamellipodium morphogenesis,"GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0035727//lysophosphatidic acid binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0051015//actin filament binding;GO:0042802//identical protein binding",-
7430,61,438,9,291,417,11,63,106,41,109,187,0,EZR;ezrin,GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0005884//actin filament;GO:0001726//ruffle;GO:0016020//membrane;GO:0036064//ciliary basal body;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0005902//microvillus;GO:0044297//cell body;GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0030863//cortical cytoskeleton;GO:0097454//Schwann cell microvillus;GO:0031528//microvillus membrane;GO:0001931//uropod;GO:0044393//microspike;GO:0045121//membrane raft;GO:0097449//astrocyte projection;GO:0030315//T-tubule;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0019898//extrinsic component of membrane;GO:0051286//cell tip;GO:0016324//apical plasma membrane;GO:0031982//vesicle,GO:0008360//regulation of cell shape;GO:0010628//positive regulation of gene expression;GO:0007411//axon guidance;GO:0051017//actin filament bundle assembly;GO:0046847//filopodium assembly;GO:0007159//leukocyte cell-cell adhesion;GO:0031623//receptor internalization;GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0022614//membrane to membrane docking;GO:0061028//establishment of endothelial barrier,GO:0019904//protein domain specific binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0050839//cell adhesion molecule binding;GO:0051015//actin filament binding,K08007//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton
7431,0,122,2,82,129,0,0,205,0,0,26,0,VIM;vimentin,GO:0005777//peroxisome;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0005882//intermediate filament;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0045111//intermediate filament cytoskeleton,GO:0010628//positive regulation of gene expression;GO:0045109//intermediate filament organization;GO:0006928//cellular component movement;GO:0070307//lens fiber cell development;GO:0006915//apoptotic process;GO:0014002//astrocyte development;GO:0010977//negative regulation of neuron projection development;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0060020//Bergmann glial cell differentiation;GO:0030049//muscle filament sliding;GO:0016032//viral process,GO:0001948//glycoprotein binding;GO:0005200//structural constituent of cytoskeleton;GO:0042802//identical protein binding;GO:0003725//double-stranded RNA binding;GO:0097110//scaffold protein binding;GO:0008022//protein C-terminus binding;GO:0005212//structural constituent of eye lens;GO:0005515//protein binding,K07606//Epstein-Barr virus infection
7432,0,0,0,0,0,0,0,0,30,0,0,0,VIP;vasoactive intestinal peptide,GO:0043025//neuronal cell body;GO:0005576//extracellular region,GO:0045732//positive regulation of protein catabolic process;GO:0007611//learning or memory;GO:0045909//positive regulation of vasodilation;GO:0008284//positive regulation of cell proliferation;GO:0032880//regulation of protein localization;GO:0060406//positive regulation of penile erection;GO:0007589//body fluid secretion;GO:0010579//positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0043267//negative regulation of potassium ion transport;GO:0051930//regulation of sensory perception of pain;GO:0009966//regulation of signal transduction;GO:0048662//negative regulation of smooth muscle cell proliferation,GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding,-
7433,0,0,0,0,0,0,0,0,39,0,0,0,VIPR1;vasoactive intestinal peptide receptor 1,GO:0043235//receptor complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,"GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0006936//muscle contraction;GO:0007187//G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0008284//positive regulation of cell proliferation;GO:0006955//immune response;GO:0007586//digestion",GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0005515//protein binding,K04589//Neuroactive ligand-receptor interaction
7434,0,0,0,0,0,15,0,98,12,0,0,0,VIPR2;vasoactive intestinal peptide receptor 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007267//cell-cell signaling;GO:0007190//activation of adenylate cyclase activity;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004999//vasoactive intestinal polypeptide receptor activity;GO:0004930//G-protein coupled receptor activity,K04590//Neuroactive ligand-receptor interaction
7436,127,0,0,3,0,0,0,1,35,0,22,1,VLDLR;very low density lipoprotein receptor,GO:0043235//receptor complex;GO:0005905//coated pit;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0034361//very-low-density lipoprotein particle;GO:0005886//plasma membrane,GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport;GO:0007399//nervous system development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034447//very-low-density lipoprotein particle clearance;GO:1900006//positive regulation of dendrite development;GO:0038026//reelin-mediated signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0007165//signal transduction;GO:0007613//memory;GO:0045860//positive regulation of protein kinase activity;GO:0034436//glycoprotein transport;GO:0021517//ventral spinal cord development,GO:0001948//glycoprotein binding;GO:0038025//reelin receptor activity;GO:0034185//apolipoprotein binding;GO:0034189//very-low-density lipoprotein particle binding;GO:0034437//glycoprotein transporter activity;GO:0005515//protein binding;GO:0048306//calcium-dependent protein binding;GO:0030229//very-low-density lipoprotein particle receptor activity;GO:0005509//calcium ion binding;GO:0005041//low-density lipoprotein receptor activity,K12473//Toxoplasmosis;Hepatitis C;Endocytosis;Bile secretion
7439,0,0,0,0,0,16,0,0,0,0,0,0,BEST1;bestrophin 1,GO:0005829//cytosol;GO:0034707//chloride channel complex;GO:0016323//basolateral plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0030321//transepithelial chloride transport;GO:1902476//chloride transmembrane transport;GO:0006821//chloride transport;GO:0007601//visual perception;GO:0050908//detection of light stimulus involved in visual perception;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0051924//regulation of calcium ion transport,GO:0005254//chloride channel activity,-
744,245,1,0,37,45,23,43,57,31,0,11,0,MPPED2;metallophosphoesterase domain containing 2,-,GO:0008152//metabolic process;GO:0007399//nervous system development,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
7441,0,0,0,0,0,0,0,0,0,0,3,0,VPREB1;pre-B lymphocyte 1,-,-,-,-
7442,0,0,0,0,0,15,56,1,38,134,0,1,"TRPV1;transient receptor potential cation channel, subfamily V, member 1",GO:0045211//postsynaptic membrane;GO:0032591//dendritic spine membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0031226//intrinsic component of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0050955//thermoception;GO:0071312//cellular response to alkaloid;GO:0006810//transport;GO:0034220//ion transmembrane transport;GO:0007635//chemosensory behavior;GO:0007166//cell surface receptor signaling pathway;GO:0071318//cellular response to ATP;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport,GO:0004888//transmembrane signaling receptor activity;GO:0005262//calcium channel activity;GO:0051219//phosphoprotein binding;GO:0015278//calcium-release channel activity;GO:0005231//excitatory extracellular ligand-gated ion channel activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,K05222//Neuroactive ligand-receptor interaction
7443,0,0,0,2,0,33,0,0,0,0,8,0,VRK1;vaccinia related kinase 1,GO:0005730//nucleolus;GO:0005795//Golgi stack;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005654//nucleoplasm,GO:0007067//mitotic nuclear division;GO:0046777//protein autophosphorylation;GO:0007077//mitotic nuclear envelope disassembly;GO:0090166//Golgi disassembly;GO:0043987//histone H3-S10 phosphorylation;GO:0072355//histone H3-T3 phosphorylation;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0007084//mitotic nuclear envelope reassembly,GO:0005524//ATP binding;GO:0072354//histone kinase activity (H3-T3 specific);GO:0031493//nucleosomal histone binding;GO:0004674//protein serine/threonine kinase activity;GO:0035175//histone kinase activity (H3-S10 specific);GO:0004672//protein kinase activity;GO:0005515//protein binding,-
7444,0,34,27,27,41,0,0,77,6,0,9,0,VRK2;vaccinia related kinase 2,GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0016032//viral process;GO:0034599//cellular response to oxidative stress;GO:2000659//regulation of interleukin-1-mediated signaling pathway;GO:0046777//protein autophosphorylation;GO:0043408//regulation of MAPK cascade;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
7447,0,0,0,0,0,0,43,0,32,0,16,0,VSNL1;visinin-like 1,-,GO:0019722//calcium-mediated signaling,GO:0005509//calcium ion binding,K13764//Phototransduction
7448,12,0,0,0,0,0,25,0,13,0,0,0,VTN;vitronectin,GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0071062//alphav-beta3 integrin-vitronectin complex;GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix,GO:0090303//positive regulation of wound healing;GO:0035987//endodermal cell differentiation;GO:0033627//cell adhesion mediated by integrin;GO:0010811//positive regulation of cell-substrate adhesion;GO:0006955//immune response;GO:0032092//positive regulation of protein binding;GO:0014911//positive regulation of smooth muscle cell migration;GO:0030449//regulation of complement activation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0045087//innate immune response;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0030195//negative regulation of blood coagulation;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0006898//receptor-mediated endocytosis;GO:0010951//negative regulation of endopeptidase activity;GO:0061302//smooth muscle cell-matrix adhesion;GO:0007160//cell-matrix adhesion;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0005178//integrin binding;GO:0008201//heparin binding;GO:0030247//polysaccharide binding;GO:0005044//scavenger receptor activity;GO:0050840//extracellular matrix binding,K06251//ECM-receptor interaction;Focal adhesion
745,61,0,0,0,11,28,23,57,76,87,5,0,MYRF;myelin regulatory factor,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0031643//positive regulation of myelination;GO:0006508//proteolysis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048709//oligodendrocyte differentiation;GO:0014003//oligodendrocyte development;GO:0032286//central nervous system myelin maintenance;GO:0022010//central nervous system myelination",GO:0008233//peptidase activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7450,90,0,21,0,0,30,39,258,206,112,28,0,VWF;von Willebrand factor,GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0031093//platelet alpha granule lumen;GO:0033093//Weibel-Palade body;GO:0031091//platelet alpha granule;GO:0031012//extracellular matrix,"GO:0030198//extracellular matrix organization;GO:0007599//hemostasis;GO:0031589//cell-substrate adhesion;GO:0051260//protein homooligomerization;GO:0009611//response to wounding;GO:0001889//liver development;GO:0030168//platelet activation;GO:0007597//blood coagulation, intrinsic pathway;GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0001890//placenta development;GO:0007155//cell adhesion",GO:0001948//glycoprotein binding;GO:0047485//protein N-terminus binding;GO:0051087//chaperone binding;GO:0042802//identical protein binding;GO:0002020//protease binding;GO:0019865//immunoglobulin binding;GO:0005518//collagen binding;GO:0042803//protein homodimerization activity;GO:0005178//integrin binding;GO:0005515//protein binding,K03900//Complement and coagulation cascades;Focal adhesion;ECM-receptor interaction
7453,0,81,0,7,12,0,0,0,68,81,7,0,WARS;tryptophanyl-tRNA synthetase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0001525//angiogenesis;GO:0006436//tryptophanyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0006412//translation;GO:0045765//regulation of angiogenesis,GO:0005524//ATP binding;GO:0004830//tryptophan-tRNA ligase activity;GO:0005515//protein binding,K01867//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Aminoacyl-tRNA biosynthesis;Metabolic pathways
7454,0,0,0,0,0,13,1,0,29,0,8,0,WAS;Wiskott-Aldrich syndrome,GO:0005911//cell-cell junction;GO:0070062//extracellular vesicular exosome;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0012506//vesicle membrane,GO:0016197//endosomal transport;GO:0042110//T cell activation;GO:0050852//T cell receptor signaling pathway;GO:0008544//epidermis development;GO:0030041//actin filament polymerization;GO:0007596//blood coagulation;GO:0006955//immune response;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0050790//regulation of catalytic activity;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0008154//actin polymerization or depolymerization;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0030048//actin filament-based movement;GO:0006952//defense response,GO:0043274//phospholipase binding;GO:0003779//actin binding;GO:0005083//small GTPase regulator activity;GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding,K05747//Regulation of actin cytoskeleton;Adherens junction;Pathogenic Escherichia coli infection;Salmonella infection;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Shigellosis;Fc gamma R-mediated phagocytosis
7455,100,0,0,0,10,80,47,1,65,6,13,444,ZAN;zonadhesin,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0016337//single organismal cell-cell adhesion;GO:0007339//binding of sperm to zona pellucida,-,K13908//Salivary secretion
7456,0,0,0,0,0,7,0,87,4,0,0,0,"WIPF1;WAS/WASL interacting protein family, member 1",GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0015629//actin cytoskeleton;GO:0001726//ruffle;GO:0005884//actin filament,GO:0030048//actin filament-based movement;GO:0045087//innate immune response;GO:0006461//protein complex assembly;GO:0008154//actin polymerization or depolymerization;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0051707//response to other organism,GO:0005515//protein binding;GO:0005522//profilin binding;GO:0003779//actin binding,-
7458,0,44,0,34,221,15,1,126,40,0,0,0,EIF4H;eukaryotic translation initiation factor 4H,GO:0005829//cytosol;GO:0016020//membrane;GO:0048471//perinuclear region of cytoplasm;GO:0016281//eukaryotic translation initiation factor 4F complex,GO:0016032//viral process;GO:0006446//regulation of translational initiation;GO:0048589//developmental growth;GO:0006412//translation;GO:0006413//translational initiation;GO:0019953//sexual reproduction;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression,"GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity",K03258//mTOR signaling pathway;RNA transport
746,0,45,0,1,21,0,5,0,10,0,0,0,TMEM258;transmembrane protein 258,GO:0016021//integral component of membrane,-,-,-
7461,33,0,39,0,5,16,0,5,52,0,0,0,CLIP2;CAP-GLY domain containing linker protein 2,GO:0005875//microtubule associated complex;GO:0005881//cytoplasmic microtubule;GO:0035371//microtubule plus-end,-,GO:0051010//microtubule plus-end binding,-
7462,93,39,0,0,15,0,0,2,0,0,52,0,"LAT2;linker for activation of T cells family, member 2",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0042629//mast cell granule;GO:0016021//integral component of membrane,GO:0042113//B cell activation;GO:0035556//intracellular signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050853//B cell receptor signaling pathway;GO:0045087//innate immune response;GO:0019722//calcium-mediated signaling;GO:0043303//mast cell degranulation,GO:0005515//protein binding;GO:0042169//SH2 domain binding,-
7464,1,32,2,20,117,7,45,84,28,0,1,0,"CORO2A;coronin, actin binding protein, 2A",GO:0017053//transcriptional repressor complex;GO:0015629//actin cytoskeleton,GO:0030036//actin cytoskeleton organization;GO:0035556//intracellular signal transduction,GO:0051015//actin filament binding,-
7465,0,0,0,14,36,0,31,0,19,0,13,0,WEE1;WEE1 G2 checkpoint kinase,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000086//G2/M transition of mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000278//mitotic cell cycle;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0007596//blood coagulation;GO:0007067//mitotic nuclear division;GO:0048812//neuron projection morphogenesis;GO:0000082//G1/S transition of mitotic cell cycle;GO:0030010//establishment of cell polarity,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0000287//magnesium ion binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K06632//Cell cycle
7466,0,0,42,0,9,15,0,73,17,1,29,0,WFS1;Wolfram syndrome 1 (wolframin),GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0030425//dendrite,GO:0001822//kidney development;GO:0045927//positive regulation of growth;GO:0042593//glucose homeostasis;GO:0007605//sensory perception of sound;GO:0022417//protein maturation by protein folding;GO:0050877//neurological system process;GO:0043069//negative regulation of programmed cell death;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0042048//olfactory behavior;GO:0050821//protein stabilization;GO:0070845//polyubiquitinated misfolded protein transport;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0051928//positive regulation of calcium ion transport;GO:0006983//ER overload response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007601//visual perception;GO:0043524//negative regulation of neuron apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0055074//calcium ion homeostasis;GO:0003091//renal water homeostasis;GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0044267//cellular protein metabolic process;GO:0045862//positive regulation of proteolysis;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0051247//positive regulation of protein metabolic process,GO:0031625//ubiquitin protein ligase binding;GO:0048306//calcium-dependent protein binding;GO:0051117//ATPase binding;GO:0033613//activating transcription factor binding;GO:0005516//calmodulin binding;GO:0005215//transporter activity,K14020//Protein processing in endoplasmic reticulum
7468,0,0,0,30,22,0,0,0,80,0,2,0,WHSC1;Wolf-Hirschhorn syndrome candidate 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0005694//chromosome;GO:0005730//nucleolus,"GO:0060348//bone development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0003289//atrial septum primum morphogenesis;GO:0003290//atrial septum secundum morphogenesis;GO:0034968//histone lysine methylation;GO:0003149//membranous septum morphogenesis",GO:0003682//chromatin binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,K11424//Transcriptional misregulation in cancer;Lysine degradation
7469,0,0,0,0,0,13,0,2,0,0,8,0,NELFA;negative elongation factor complex member A,GO:0005730//nucleolus;GO:0032021//NELF complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0010467//gene expression;GO:0050434//positive regulation of viral transcription;GO:0007275//multicellular organismal development;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0003682//chromatin binding,-
747,112,0,1,0,0,22,36,0,47,239,14,0,"DAGLA;diacylglycerol lipase, alpha",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0046340//diacylglycerol catabolic process;GO:0030168//platelet activation;GO:0042136//neurotransmitter biosynthetic process;GO:0071926//endocannabinoid signaling pathway;GO:0008219//cell death;GO:0007405//neuroblast proliferation;GO:0007596//blood coagulation;GO:0019369//arachidonic acid metabolic process,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,K13806//Retrograde endocannabinoid signaling;Phototransduction - fly
7472,95,0,0,0,0,0,0,0,14,0,7,0,WNT2;wingless-type MMTV integration site family member 2,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016055//Wnt signaling pathway;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030182//neuron differentiation;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0071300//cellular response to retinoic acid;GO:0055009//atrial cardiac muscle tissue morphogenesis;GO:0061072//iris morphogenesis;GO:0030324//lung development;GO:0060492//lung induction;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0008284//positive regulation of cell proliferation;GO:0045165//cell fate commitment;GO:0007267//cell-cell signaling;GO:0002088//lens development in camera-type eye;GO:0060716//labyrinthine layer blood vessel development;GO:0061180//mammary gland epithelium development;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0048146//positive regulation of fibroblast proliferation,GO:0048018//receptor agonist activity;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005109//frizzled binding,K00182//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection
7473,0,0,2,0,0,0,32,1,21,0,11,0,"WNT3;wingless-type MMTV integration site family, member 3",GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005578//proteinaceous extracellular matrix,GO:0060323//head morphogenesis;GO:0009948//anterior/posterior axis specification;GO:0035115//embryonic forelimb morphogenesis;GO:0030182//neuron differentiation;GO:0044339//canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0071300//cellular response to retinoic acid;GO:0000902//cell morphogenesis;GO:0009950//dorsal/ventral axis specification;GO:0001707//mesoderm formation;GO:0045165//cell fate commitment;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0060064//Spemann organizer formation at the anterior end of the primitive streak;GO:0035116//embryonic hindlimb morphogenesis;GO:0061180//mammary gland epithelium development;GO:0044338//canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0048697//positive regulation of collateral sprouting in absence of injury;GO:0007276//gamete generation;GO:0060174//limb bud formation;GO:0060070//canonical Wnt signaling pathway;GO:0010628//positive regulation of gene expression;GO:0007411//axon guidance,GO:0019904//protein domain specific binding;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0048018//receptor agonist activity,K00312//Wnt signaling pathway;HTLV-I infection;Pathways in cancer;Hedgehog signaling pathway;Melanogenesis;Basal cell carcinoma
7474,0,0,0,0,0,12,3,0,30,0,16,0,"WNT5A;wingless-type MMTV integration site family, member 5A",GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface,"GO:0061354//planar cell polarity pathway involved in pericardium morphogenesis;GO:0045732//positive regulation of protein catabolic process;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0001667//ameboidal cell migration;GO:0001756//somitogenesis;GO:0071277//cellular response to calcium ion;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060065//uterus development;GO:0010033//response to organic substance;GO:0090009//primitive streak formation;GO:0007411//axon guidance;GO:0001938//positive regulation of endothelial cell proliferation;GO:0061347//planar cell polarity pathway involved in outflow tract morphogenesis;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0045599//negative regulation of fat cell differentiation;GO:0003408//optic cup formation involved in camera-type eye development;GO:0060070//canonical Wnt signaling pathway;GO:0001947//heart looping;GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030514//negative regulation of BMP signaling pathway;GO:0060029//convergent extension involved in organogenesis;GO:0061036//positive regulation of cartilage development;GO:0010976//positive regulation of neuron projection development;GO:0090037//positive regulation of protein kinase C signaling;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0021891//olfactory bulb interneuron development;GO:0060686//negative regulation of prostatic bud formation;GO:0048806//genitalia development;GO:0030182//neuron differentiation;GO:0007257//activation of JUN kinase activity;GO:0002088//lens development in camera-type eye;GO:0036342//post-anal tail morphogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0060907//positive regulation of macrophage cytokine production;GO:0061349//planar cell polarity pathway involved in cardiac right atrium morphogenesis;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0043066//negative regulation of apoptotic process;GO:0060324//face development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030825//positive regulation of cGMP metabolic process;GO:0010595//positive regulation of endothelial cell migration;GO:0001736//establishment of planar polarity;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0048706//embryonic skeletal system development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0003323//type B pancreatic cell development;GO:0060599//lateral sprouting involved in mammary gland duct morphogenesis;GO:0001837//epithelial to mesenchymal transition;GO:0060157//urinary bladder development;GO:0045766//positive regulation of angiogenesis;GO:0045165//cell fate commitment;GO:0032729//positive regulation of interferon-gamma production;GO:0060068//vagina development;GO:0061350//planar cell polarity pathway involved in cardiac muscle tissue morphogenesis;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0000187//activation of MAPK activity;GO:2000484//positive regulation of interleukin-8 secretion;GO:0048850//hypophysis morphogenesis;GO:0042733//embryonic digit morphogenesis;GO:0042060//wound healing;GO:0060744//mammary gland branching involved in thelarche;GO:0045836//positive regulation of meiosis;GO:0071346//cellular response to interferon-gamma;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0008595//anterior/posterior axis specification, embryo;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0006468//protein phosphorylation;GO:0045778//positive regulation of ossification;GO:0040037//negative regulation of fibroblast growth factor receptor signaling pathway;GO:0030324//lung development;GO:0030216//keratinocyte differentiation;GO:0071425//hematopoietic stem cell proliferation;GO:0034613//cellular protein localization;GO:0043032//positive regulation of macrophage activation;GO:0051216//cartilage development;GO:0071542//dopaminergic neuron differentiation;GO:0007494//midgut development;GO:0060638//mesenchymal-epithelial cell signaling;GO:0060750//epithelial cell proliferation involved in mammary gland duct elongation;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:0060021//palate development;GO:0046330//positive regulation of JNK cascade;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0048146//positive regulation of fibroblast proliferation;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0007442//hindgut morphogenesis;GO:0090103//cochlea morphogenesis;GO:0016055//Wnt signaling pathway;GO:0001843//neural tube closure;GO:0051964//negative regulation of synapse assembly;GO:0060067//cervix development;GO:0045080//positive regulation of chemokine biosynthetic process;GO:0060760//positive regulation of response to cytokine stimulus;GO:0032148//activation of protein kinase B activity;GO:0061348//planar cell polarity pathway involved in ventricular septum morphogenesis;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0008584//male gonad development;GO:0071300//cellular response to retinoic acid;GO:0010820//positive regulation of T cell chemotaxis;GO:0050919//negative chemotaxis;GO:0050729//positive regulation of inflammatory response",GO:0044212//transcription regulatory region DNA binding;GO:0005115//receptor tyrosine kinase-like orphan receptor binding;GO:0005125//cytokine activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0019904//protein domain specific binding;GO:0005109//frizzled binding;GO:0005110//frizzled-2 binding;GO:0048018//receptor agonist activity,K00444//HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Hedgehog signaling pathway;Melanogenesis;Basal cell carcinoma
7475,0,0,47,0,0,0,13,0,10,0,0,0,"WNT6;wingless-type MMTV integration site family, member 6",GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0005796//Golgi lumen;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen,"GO:0071300//cellular response to retinoic acid;GO:0061303//cornea development in camera-type eye;GO:0072079//nephron tubule formation;GO:0070172//positive regulation of tooth mineralization;GO:0060684//epithelial-mesenchymal cell signaling;GO:0009798//axis specification;GO:0030182//neuron differentiation;GO:0010628//positive regulation of gene expression;GO:0045165//cell fate commitment;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0016055//Wnt signaling pathway",GO:0005109//frizzled binding,K00445//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Pathways in cancer;Hedgehog signaling pathway
7476,0,0,0,0,0,0,0,0,21,0,0,0,"WNT7A;wingless-type MMTV integration site family, member 7A",GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005796//Golgi lumen;GO:0005886//plasma membrane,"GO:0070307//lens fiber cell development;GO:0031133//regulation of axon diameter;GO:0001502//cartilage condensation;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0035567//non-canonical Wnt signaling pathway;GO:0035115//embryonic forelimb morphogenesis;GO:0022009//central nervous system vasculogenesis;GO:0007548//sex differentiation;GO:0060066//oviduct development;GO:0032355//response to estradiol;GO:0035019//somatic stem cell maintenance;GO:0048103//somatic stem cell division;GO:0014719//skeletal muscle satellite cell activation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0060021//palate development;GO:0007269//neurotransmitter secretion;GO:0046330//positive regulation of JNK cascade;GO:0043066//negative regulation of apoptotic process;GO:0021846//cell proliferation in forebrain;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0035116//embryonic hindlimb morphogenesis;GO:0008105//asymmetric protein localization;GO:0021707//cerebellar granule cell differentiation;GO:0030182//neuron differentiation;GO:0050768//negative regulation of neurogenesis;GO:0035659//Wnt signaling pathway involved in wound healing, spreading of epidermal cells;GO:0051965//positive regulation of synapse assembly;GO:0000578//embryonic axis specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002062//chondrocyte differentiation;GO:0050808//synapse organization;GO:0061038//uterus morphogenesis;GO:0009953//dorsal/ventral pattern formation;GO:0060070//canonical Wnt signaling pathway;GO:0042733//embryonic digit morphogenesis;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0048864//stem cell development;GO:0045165//cell fate commitment;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030010//establishment of cell polarity",GO:0005102//receptor binding;GO:0005109//frizzled binding;GO:0005125//cytokine activity;GO:0048018//receptor agonist activity,K00572//Hedgehog signaling pathway;Pathways in cancer;HTLV-I infection;Wnt signaling pathway;Basal cell carcinoma;Melanogenesis
7477,95,0,0,0,0,25,0,0,0,0,0,0,"WNT7B;wingless-type MMTV integration site family, member 7B",GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005796//Golgi lumen,GO:0001701//in utero embryonic development;GO:0060484//lung-associated mesenchyme development;GO:0060535//trachea cartilage morphogenesis;GO:0060033//anatomical structure regression;GO:0060482//lobar bronchus development;GO:0045165//cell fate commitment;GO:0060669//embryonic placenta morphogenesis;GO:0048812//neuron projection morphogenesis;GO:0051384//response to glucocorticoid;GO:0042592//homeostatic process;GO:0072053//renal inner medulla development;GO:0045669//positive regulation of osteoblast differentiation;GO:0061180//mammary gland epithelium development;GO:0060428//lung epithelium development;GO:0060710//chorio-allantoic fusion;GO:0060070//canonical Wnt signaling pathway;GO:0045879//negative regulation of smoothened signaling pathway;GO:0050808//synapse organization;GO:0072061//inner medullary collecting duct development;GO:0016332//establishment or maintenance of polarity of embryonic epithelium;GO:0044237//cellular metabolic process;GO:0030182//neuron differentiation;GO:0007257//activation of JUN kinase activity;GO:0072236//metanephric loop of Henle development;GO:0030324//lung development;GO:0048144//fibroblast proliferation;GO:0032364//oxygen homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0072205//metanephric collecting duct development;GO:0003338//metanephros morphogenesis;GO:1902262//apoptotic process involved in patterning of blood vessels;GO:0072054//renal outer medulla development;GO:0060425//lung morphogenesis;GO:0060560//developmental growth involved in morphogenesis;GO:0048568//embryonic organ development;GO:0010628//positive regulation of gene expression;GO:0046330//positive regulation of JNK cascade;GO:0021871//forebrain regionalization;GO:0072089//stem cell proliferation;GO:0072060//outer medullary collecting duct development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0016055//Wnt signaling pathway;GO:0072207//metanephric epithelium development;GO:0051145//smooth muscle cell differentiation;GO:0022009//central nervous system vasculogenesis;GO:0071300//cellular response to retinoic acid;GO:0032536//regulation of cell projection size;GO:0070307//lens fiber cell development,GO:0005109//frizzled binding,K00572//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Hedgehog signaling pathway;Pathways in cancer
7479,0,0,0,0,0,25,0,0,9,0,0,0,"WNT8B;wingless-type MMTV integration site family, member 8B",GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0030182//neuron differentiation;GO:0071300//cellular response to retinoic acid;GO:0010628//positive regulation of gene expression;GO:0007399//nervous system development;GO:0007369//gastrulation;GO:0032526//response to retinoic acid;GO:0010629//negative regulation of gene expression;GO:0045165//cell fate commitment;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction;GO:0048263//determination of dorsal identity;GO:0032355//response to estradiol,GO:0005109//frizzled binding,K00714//Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection;Basal cell carcinoma;Melanogenesis
7480,0,0,0,0,0,0,0,0,9,0,0,0,"WNT10B;wingless-type MMTV integration site family, member 10B",GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0061196//fungiform papilla development;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0014835//myoblast differentiation involved in skeletal muscle regeneration;GO:0050680//negative regulation of epithelial cell proliferation;GO:0030182//neuron differentiation;GO:0071425//hematopoietic stem cell proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043065//positive regulation of apoptotic process;GO:0045899//positive regulation of RNA polymerase II transcriptional preinitiation complex assembly;GO:0045165//cell fate commitment;GO:0071374//cellular response to parathyroid hormone stimulus;GO:0045669//positive regulation of osteoblast differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0050821//protein stabilization;GO:0002062//chondrocyte differentiation;GO:0045599//negative regulation of fat cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007224//smoothened signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0007050//cell cycle arrest;GO:0016055//Wnt signaling pathway;GO:0060346//bone trabecula formation;GO:0071300//cellular response to retinoic acid;GO:0071320//cellular response to cAMP;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0050909//sensory perception of taste;GO:0071464//cellular response to hydrostatic pressure;GO:0008284//positive regulation of cell proliferation;GO:0006629//lipid metabolic process;GO:0032434//regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0048741//skeletal muscle fiber development;GO:0030858//positive regulation of epithelial cell differentiation;GO:0051885//positive regulation of anagen;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0048641//regulation of skeletal muscle tissue development,GO:0048018//receptor agonist activity;GO:0005109//frizzled binding,K01357//Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection;Basal cell carcinoma;Melanogenesis
7481,0,0,0,0,0,0,24,0,25,0,0,0,"WNT11;wingless-type MMTV integration site family, member 11",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005737//cytoplasm,"GO:0060548//negative regulation of cell death;GO:0030282//bone mineralization;GO:0035567//non-canonical Wnt signaling pathway;GO:0031667//response to nutrient levels;GO:0071300//cellular response to retinoic acid;GO:0048844//artery morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0001649//osteoblast differentiation;GO:0060412//ventricular septum morphogenesis;GO:0048706//embryonic skeletal system development;GO:0030336//negative regulation of cell migration;GO:0030308//negative regulation of cell growth;GO:0060021//palate development;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0034394//protein localization to cell surface;GO:0060675//ureteric bud morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0006468//protein phosphorylation;GO:0090272//negative regulation of fibroblast growth factor production;GO:0030182//neuron differentiation;GO:0032320//positive regulation of Ras GTPase activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070830//tight junction assembly;GO:0045860//positive regulation of protein kinase activity;GO:0090037//positive regulation of protein kinase C signaling;GO:0060197//cloacal septation;GO:0051496//positive regulation of stress fiber assembly;GO:0072177//mesonephric duct development;GO:0061037//negative regulation of cartilage development;GO:0032915//positive regulation of transforming growth factor beta2 production;GO:0072201//negative regulation of mesenchymal cell proliferation;GO:0061101//neuroendocrine cell differentiation;GO:0030325//adrenal gland development;GO:0030335//positive regulation of cell migration;GO:0060070//canonical Wnt signaling pathway;GO:0060484//lung-associated mesenchyme development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045165//cell fate commitment",GO:0005099//Ras GTPase activator activity;GO:0030295//protein kinase activator activity;GO:0044212//transcription regulatory region DNA binding;GO:0005109//frizzled binding,K01384//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection
7482,0,0,0,0,0,0,57,0,28,0,0,0,"WNT2B;wingless-type MMTV integration site family, member 2B",GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0005578//proteinaceous extracellular matrix,GO:0002062//chondrocyte differentiation;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0021871//forebrain regionalization;GO:0061303//cornea development in camera-type eye;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0002088//lens development in camera-type eye;GO:0060638//mesenchymal-epithelial cell signaling;GO:0045165//cell fate commitment;GO:0008584//male gonad development;GO:0030182//neuron differentiation;GO:0071425//hematopoietic stem cell proliferation;GO:0060492//lung induction;GO:0061072//iris morphogenesis;GO:0016055//Wnt signaling pathway;GO:0009267//cellular response to starvation,GO:0005109//frizzled binding,K00182//Melanogenesis;Basal cell carcinoma;HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Hedgehog signaling pathway
7483,0,0,0,0,0,0,0,1,30,4,0,0,"WNT9A;wingless-type MMTV integration site family, member 9A",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix,GO:0016055//Wnt signaling pathway;GO:0048704//embryonic skeletal system morphogenesis;GO:0007275//multicellular organismal development;GO:0045880//positive regulation of smoothened signaling pathway;GO:0060548//negative regulation of cell death;GO:0071300//cellular response to retinoic acid;GO:0061072//iris morphogenesis;GO:0045597//positive regulation of cell differentiation;GO:0030182//neuron differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0072498//embryonic skeletal joint development;GO:0007267//cell-cell signaling;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0032331//negative regulation of chondrocyte differentiation;GO:0045165//cell fate commitment;GO:0007093//mitotic cell cycle checkpoint;GO:0008285//negative regulation of cell proliferation;GO:0061037//negative regulation of cartilage development;GO:0060070//canonical Wnt signaling pathway;GO:0061303//cornea development in camera-type eye,GO:0005109//frizzled binding,K01064//HTLV-I infection;Wnt signaling pathway;Hedgehog signaling pathway;Pathways in cancer;Melanogenesis;Basal cell carcinoma
7484,0,0,0,0,0,0,0,0,23,0,0,0,"WNT9B;wingless-type MMTV integration site family, member 9B",GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0030539//male genitalia development;GO:0001701//in utero embryonic development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0072181//mesonephric duct formation;GO:0007267//cell-cell signaling;GO:0003339//regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0045165//cell fate commitment;GO:0001932//regulation of protein phosphorylation;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0061038//uterus morphogenesis;GO:0060021//palate development;GO:0060070//canonical Wnt signaling pathway;GO:0061303//cornea development in camera-type eye;GO:0072003//kidney rudiment formation;GO:0009786//regulation of asymmetric cell division;GO:0016055//Wnt signaling pathway;GO:0009267//cellular response to starvation;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0032526//response to retinoic acid;GO:0035150//regulation of tube size;GO:0072174//metanephric tubule formation;GO:0007275//multicellular organismal development;GO:0030182//neuron differentiation;GO:0072046//establishment of planar polarity involved in nephron morphogenesis;GO:0072044//collecting duct development;GO:0071300//cellular response to retinoic acid;GO:0043085//positive regulation of catalytic activity",GO:0005109//frizzled binding,K01064//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Pathways in cancer;Hedgehog signaling pathway
7485,0,0,0,3,0,0,25,0,0,0,3,0,WRB;tryptophan rich basic protein,GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0071816//tail-anchored membrane protein insertion into ER membrane,-,-
7486,49,13,0,6,0,22,35,0,59,0,30,0,"WRN;Werner syndrome, RecQ helicase-like",GO:0005813//centrosome;GO:0032389//MutLalpha complex;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0031297//replication fork processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0000723//telomere maintenance;GO:0010225//response to UV-C;GO:0032508//DNA duplex unwinding;GO:0042981//regulation of apoptotic process;GO:0007568//aging;GO:0006974//cellular response to DNA damage stimulus;GO:0010259//multicellular organismal aging;GO:0006284//base-excision repair;GO:0006259//DNA metabolic process;GO:0032066//nucleolus to nucleoplasm transport;GO:0006200//ATP catabolic process;GO:0006302//double-strand break repair;GO:0009267//cellular response to starvation;GO:0006310//DNA recombination;GO:0001302//replicative cell aging;GO:0000731//DNA synthesis involved in DNA repair;GO:0040009//regulation of growth rate;GO:0051345//positive regulation of hydrolase activity;GO:0007569//cell aging;GO:0006260//DNA replication;GO:0071480//cellular response to gamma radiation;GO:0006979//response to oxidative stress,GO:0016887//ATPase activity;GO:0030145//manganese ion binding;GO:0004386//helicase activity;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0003678//DNA helicase activity;GO:0032403//protein complex binding;GO:0042803//protein homodimerization activity;GO:0051880//G-quadruplex DNA binding;GO:0000287//magnesium ion binding;GO:0009378//four-way junction helicase activity;GO:0003677//DNA binding;GO:0004527//exonuclease activity;GO:0008408//3'-5' exonuclease activity;GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0000405//bubble DNA binding;GO:0005515//protein binding;GO:0043138//3'-5' DNA helicase activity;GO:0000403//Y-form DNA binding,-
7490,0,0,0,16,0,20,0,0,7,0,0,0,WT1;Wilms tumor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0016607//nuclear speck,"GO:2001076//positive regulation of metanephric ureteric bud development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060539//diaphragm development;GO:0060421//positive regulation of heart growth;GO:0030325//adrenal gland development;GO:0008380//RNA splicing;GO:0060231//mesenchymal to epithelial transition;GO:0001570//vasculogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0007281//germ cell development;GO:0072075//metanephric mesenchyme development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032835//glomerulus development;GO:0043065//positive regulation of apoptotic process;GO:0072284//metanephric S-shaped body morphogenesis;GO:0071371//cellular response to gonadotropin stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060923//cardiac muscle cell fate commitment;GO:0001657//ureteric bud development;GO:2000020//positive regulation of male gonad development;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061032//visceral serous pericardium development;GO:0072302//negative regulation of metanephric glomerular mesangial cell proliferation;GO:0035802//adrenal cortex formation;GO:0030308//negative regulation of cell growth;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0003156//regulation of organ formation;GO:0006351//transcription, DNA-templated;GO:0043010//camera-type eye development;GO:0007507//heart development;GO:0001822//kidney development;GO:0030539//male genitalia development;GO:0009888//tissue development;GO:0008584//male gonad development;GO:0030855//epithelial cell differentiation;GO:0007356//thorax and anterior abdomen determination;GO:0008406//gonad development;GO:0071320//cellular response to cAMP;GO:2000195//negative regulation of female gonad development;GO:0007530//sex determination;GO:0017148//negative regulation of translation;GO:0072207//metanephric epithelium development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0032836//glomerular basement membrane development;GO:0072166//posterior mesonephric tubule development",GO:0043565//sequence-specific DNA binding;GO:0003723//RNA binding;GO:0070742//C2H2 zinc finger domain binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding,K09234//Transcriptional misregulation in cancer
7494,0,33,0,46,84,0,0,0,39,271,36,0,XBP1;X-box binding protein 1,GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006366//transcription from RNA polymerase II promoter;GO:0051602//response to electrical stimulus;GO:0006955//immune response;GO:0044267//cellular protein metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071236//cellular response to antibiotic;GO:0042593//glucose homeostasis;GO:0031017//exocrine pancreas development;GO:0042493//response to drug;GO:0060096//serotonin secretion, neurotransmission;GO:0060691//epithelial cell maturation involved in salivary gland development;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:1900103//positive regulation of endoplasmic reticulum unfolded protein response",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,K09027//Protein processing in endoplasmic reticulum;HTLV-I infection
7498,1,0,0,0,0,49,73,0,86,6,13,0,XDH;xanthine dehydrogenase,GO:0005777//peroxisome;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0007595//lactation;GO:1900745//positive regulation of p38MAPK cascade;GO:0051898//negative regulation of protein kinase B signaling;GO:0006195//purine nucleotide catabolic process;GO:0001937//negative regulation of endothelial cell proliferation;GO:0055114//oxidation-reduction process;GO:2001213//negative regulation of vasculogenesis;GO:0045602//negative regulation of endothelial cell differentiation;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010629//negative regulation of gene expression;GO:0009115//xanthine catabolic process;GO:0044281//small molecule metabolic process;GO:0001933//negative regulation of protein phosphorylation;GO:1900747//negative regulation of vascular endothelial growth factor signaling pathway,"GO:0043546//molybdopterin cofactor binding;GO:0042803//protein homodimerization activity;GO:0009055//electron carrier activity;GO:0050660//flavin adenine dinucleotide binding;GO:0051537//2 iron, 2 sulfur cluster binding;GO:0005506//iron ion binding;GO:0008762//UDP-N-acetylmuramate dehydrogenase activity;GO:0004855//xanthine oxidase activity;GO:0004854//xanthine dehydrogenase activity",K00106//Drug metabolism - other enzymes;Purine metabolism;Peroxisome;Caffeine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Microbial metabolism in diverse environments
7499,0,0,0,15,0,0,26,0,0,140,0,0,XG;Xg blood group,GO:0005887//integral component of plasma membrane,-,-,-
7503,0,0,0,0,0,8,0,0,27,0,0,0,XIST;X inactive specific transcript (non-protein coding),-,-,-,-
7504,0,0,0,0,4,12,0,0,6,0,0,0,XK;X-linked Kx blood group,GO:0016021//integral component of membrane,GO:0006865//amino acid transport;GO:0006810//transport,GO:0005215//transporter activity;GO:0005515//protein binding,K08008//Leukocyte transendothelial migration;Osteoclast differentiation;Phagosome
7507,0,0,1,6,39,0,0,0,38,0,0,0,"XPA;xeroderma pigmentosum, complementation group A",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005662//DNA replication factor A complex;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0045171//intercellular bridge,"GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006979//response to oxidative stress;GO:0035264//multicellular organism growth;GO:0006289//nucleotide-excision repair;GO:0009411//response to UV;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0006281//DNA repair;GO:0009636//response to toxic substance",GO:0019904//protein domain specific binding;GO:0003684//damaged DNA binding;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K10847//Nucleotide excision repair
7508,271,1,0,14,24,39,37,0,47,0,10,0,"XPC;xeroderma pigmentosum, complementation group C",GO:0071942//XPC complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0010224//response to UV-B;GO:0006289//nucleotide-excision repair;GO:0000715//nucleotide-excision repair, DNA damage recognition;GO:1901990//regulation of mitotic cell cycle phase transition;GO:0006281//DNA repair;GO:0042493//response to drug;GO:0031573//intra-S DNA damage checkpoint",GO:0005515//protein binding;GO:0000405//bubble DNA binding;GO:0003697//single-stranded DNA binding;GO:0000404//heteroduplex DNA loop binding;GO:0003684//damaged DNA binding,K10838//Nucleotide excision repair
751071,0,0,0,0,0,0,0,0,0,7,0,0,METTL12;methyltransferase like 12,GO:0005739//mitochondrion,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
7511,0,84,0,25,31,13,57,30,34,0,0,0,"XPNPEP1;X-prolyl aminopeptidase (aminopeptidase P) 1, soluble",GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0010815//bradykinin catabolic process;GO:0006508//proteolysis,GO:0070006//metalloaminopeptidase activity;GO:0042803//protein homodimerization activity;GO:0030145//manganese ion binding;GO:0004177//aminopeptidase activity,-
7512,0,0,0,0,0,36,44,0,18,0,0,0,"XPNPEP2;X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound",GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0031225//anchored component of membrane,GO:0006508//proteolysis,GO:0046872//metal ion binding;GO:0004177//aminopeptidase activity;GO:0008237//metallopeptidase activity,K14208//Protein digestion and absorption
7514,0,53,49,88,143,25,0,0,34,0,40,3,XPO1;exportin 1,GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0030529//ribonucleoprotein complex;GO:0000776//kinetochore;GO:0015030//Cajal body;GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005642//annulate lamellae,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010824//regulation of centrosome duplication;GO:0010467//gene expression;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0019058//viral life cycle;GO:0000056//ribosomal small subunit export from nucleus;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0042493//response to drug;GO:0051028//mRNA transport;GO:0075733//intracellular transport of virus;GO:0000278//mitotic cell cycle;GO:0046825//regulation of protein export from nucleus;GO:0042176//regulation of protein catabolic process;GO:0034504//protein localization to nucleus;GO:0006611//protein export from nucleus;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000055//ribosomal large subunit export from nucleus;GO:0016032//viral process,GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding;GO:0005215//transporter activity;GO:0003723//RNA binding;GO:0008565//protein transporter activity;GO:0019904//protein domain specific binding;GO:0008536//Ran GTPase binding,K14290//Ribosome biogenesis in eukaryotes;Epstein-Barr virus infection;Influenza A;RNA transport;HTLV-I infection
7515,67,0,0,11,0,0,1,119,34,0,1,0,XRCC1;X-ray repair complementing defective repair in Chinese hamster cells 1,GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0010033//response to organic substance;GO:0006284//base-excision repair;GO:0001666//response to hypoxia;GO:0042493//response to drug;GO:0021766//hippocampus development;GO:0000012//single strand break repair;GO:0006281//DNA repair,GO:0005515//protein binding;GO:0003684//damaged DNA binding,K10803//Base excision repair
7516,0,0,0,0,0,0,0,0,20,0,0,0,XRCC2;X-ray repair complementing defective repair in Chinese hamster cells 2,GO:0033063//Rad51B-Rad51C-Rad51D-XRCC2 complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005657//replication fork,GO:0051297//centrosome organization;GO:0000278//mitotic cell cycle;GO:0000724//double-strand break repair via homologous recombination;GO:0007126//meiotic nuclear division;GO:0010332//response to gamma radiation;GO:0010165//response to X-ray;GO:0006281//DNA repair;GO:0042148//strand invasion;GO:0050769//positive regulation of neurogenesis;GO:0006200//ATP catabolic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0001701//in utero embryonic development,GO:0005515//protein binding;GO:0000400//four-way junction DNA binding;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity,K10879//Homologous recombination
7517,36,0,0,0,0,20,24,88,30,0,17,0,XRCC3;X-ray repair complementing defective repair in Chinese hamster cells 3,GO:0033065//Rad51C-XRCC3 complex;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005657//replication fork,"GO:0006310//DNA recombination;GO:0006200//ATP catabolic process;GO:0006281//DNA repair;GO:0071140//resolution of mitotic recombination intermediates;GO:0010033//response to organic substance;GO:0006974//cellular response to DNA damage stimulus;GO:0000724//double-strand break repair via homologous recombination;GO:0090267//positive regulation of mitotic cell cycle spindle assembly checkpoint;GO:0010824//regulation of centrosome duplication;GO:0000737//DNA catabolic process, endonucleolytic",GO:0008821//crossover junction endodeoxyribonuclease activity;GO:0005515//protein binding;GO:0000400//four-way junction DNA binding;GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity,K10880//Homologous recombination
7518,0,0,0,0,0,16,0,0,54,0,0,0,XRCC4;X-ray repair complementing defective repair in Chinese hamster cells 4,GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0070419//nonhomologous end joining complex;GO:0000793//condensed chromosome;GO:0030054//cell junction;GO:0005634//nucleus;GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex;GO:0032807//DNA ligase IV complex;GO:0005829//cytosol;GO:0005730//nucleolus,GO:0043524//negative regulation of neuron apoptotic process;GO:0016032//viral process;GO:0006302//double-strand break repair;GO:0006281//DNA repair;GO:0050769//positive regulation of neurogenesis;GO:0010165//response to X-ray;GO:0002328//pro-B cell differentiation;GO:0033077//T cell differentiation in thymus;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0001701//in utero embryonic development;GO:0051103//DNA ligation involved in DNA repair;GO:0051351//positive regulation of ligase activity;GO:0075713//establishment of integrated proviral latency;GO:0045190//isotype switching;GO:0010332//response to gamma radiation;GO:0007417//central nervous system development;GO:0033152//immunoglobulin V(D)J recombination;GO:0071285//cellular response to lithium ion;GO:0048146//positive regulation of fibroblast proliferation,GO:0008022//protein C-terminus binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0016874//ligase activity,K10886//Non-homologous end-joining
752,0,118,1,53,17,0,29,29,104,131,52,0,FMNL1;formin-like 1,GO:0032059//bleb;GO:0005938//cell cortex;GO:0045335//phagocytic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane,GO:0051014//actin filament severing;GO:0008360//regulation of cell shape;GO:0006929//substrate-dependent cell migration;GO:0030866//cortical actin cytoskeleton organization,GO:0051015//actin filament binding;GO:0005515//protein binding;GO:0005522//profilin binding;GO:0032794//GTPase activating protein binding;GO:0048365//Rac GTPase binding,K04512//Wnt signaling pathway
7520,0,99,0,177,296,14,0,34,26,0,0,0,XRCC5;X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining),"GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0070419//nonhomologous end joining complex;GO:0016020//membrane;GO:0000784//nuclear chromosome, telomeric region;GO:0005654//nucleoplasm;GO:0000783//nuclear telomere cap complex;GO:0043564//Ku70:Ku80 complex","GO:0060218//hematopoietic stem cell differentiation;GO:0050769//positive regulation of neurogenesis;GO:0006281//DNA repair;GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0016032//viral process;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0071398//cellular response to fatty acid;GO:0045892//negative regulation of transcription, DNA-templated;GO:0075713//establishment of integrated proviral latency;GO:0071475//cellular hyperosmotic salinity response;GO:0042493//response to drug;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0071481//cellular response to X-ray;GO:0007420//brain development;GO:0032508//DNA duplex unwinding;GO:0008283//cell proliferation;GO:0000723//telomere maintenance;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042162//telomeric DNA binding;GO:0003684//damaged DNA binding;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0005524//ATP binding;GO:0003691//double-stranded telomeric DNA binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0004003//ATP-dependent DNA helicase activity,K10885//Non-homologous end-joining
752014,1,165,45,103,106,6,0,1442,119,2,559,2,CEMP1;cementum protein 1,GO:0005737//cytoplasm,-,-,K01443//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Ribosome;Riboflavin metabolism;Metabolic pathways;ABC transporters
7525,0,28,0,50,86,0,0,0,67,0,0,0,"YES1;YES proto-oncogene 1, Src family tyrosine kinase",GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005794//Golgi apparatus;GO:0005829//cytosol,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0043114//regulation of vascular permeability;GO:0007596//blood coagulation;GO:0015758//glucose transport;GO:0046777//protein autophosphorylation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0050900//leukocyte migration;GO:0045087//innate immune response;GO:0006464//cellular protein modification process;GO:0031295//T cell costimulation,GO:0044325//ion channel binding;GO:0005515//protein binding;GO:0005154//epidermal growth factor receptor binding;GO:0005524//ATP binding;GO:0019899//enzyme binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity,K05705//Adherens junction;Tight junction
7528,0,70,0,38,112,5,12,193,34,0,85,237,YY1;YY1 transcription factor,GO:0016363//nuclear matrix;GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0031011//Ino80 complex;GO:0031519//PcG protein complex,"GO:0034696//response to prostaglandin F;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0006974//cellular response to DNA damage stimulus;GO:0009952//anterior/posterior pattern specification;GO:0007283//spermatogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0000724//double-strand break repair via homologous recombination;GO:0048593//camera-type eye morphogenesis;GO:0010225//response to UV-C;GO:0006403//RNA localization;GO:0051276//chromosome organization;GO:0006351//transcription, DNA-templated;GO:0034644//cellular response to UV",GO:0003677//DNA binding;GO:0000400//four-way junction DNA binding;GO:0003723//RNA binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044212//transcription regulatory region DNA binding,-
7529,0,97,1,79,229,0,0,0,17,0,1,0,"YWHAB;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta",GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0042470//melanosome;GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0017053//transcriptional repressor complex;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0043085//positive regulation of catalytic activity;GO:0061024//membrane organization;GO:0035329//hippo signaling;GO:0051291//protein heterooligomerization;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008286//insulin receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0035308//negative regulation of protein dephosphorylation;GO:0000165//MAPK cascade;GO:0000186//activation of MAPKK activity;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007411//axon guidance;GO:0010467//gene expression;GO:0006605//protein targeting;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0051220//cytoplasmic sequestering of protein",GO:0051219//phosphoprotein binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0042826//histone deacetylase binding;GO:0050815//phosphoserine binding;GO:0003714//transcription corepressor activity;GO:0032403//protein complex binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding,K06630//Oocyte meiosis;Neurotrophin signaling pathway;Cell cycle;Epstein-Barr virus infection;Pathogenic Escherichia coli infection
753,50,0,0,6,74,0,12,0,90,1,0,1,LDLRAD4;low density lipoprotein receptor class A domain containing 4,GO:0016021//integral component of membrane;GO:0031901//early endosome membrane;GO:0005886//plasma membrane,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0030336//negative regulation of cell migration;GO:0010991//negative regulation of SMAD protein complex assembly;GO:0010719//negative regulation of epithelial to mesenchymal transition,GO:0070412//R-SMAD binding;GO:0005515//protein binding,-
7531,0,198,2,139,494,0,20,92,9,150,0,0,"YWHAE;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon",GO:0005925//focal adhesion;GO:0005739//mitochondrion;GO:0005871//kinesin complex;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0042470//melanosome;GO:0030659//cytoplasmic vesicle membrane,GO:0021762//substantia nigra development;GO:0016032//viral process;GO:0086091//regulation of heart rate by cardiac conduction;GO:0097190//apoptotic signaling pathway;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0061024//membrane organization;GO:0035329//hippo signaling;GO:0001764//neuron migration;GO:0021987//cerebral cortex development;GO:1902309//negative regulation of peptidyl-serine dephosphorylation;GO:0003064//regulation of heart rate by hormone;GO:0006915//apoptotic process;GO:0021766//hippocampus development;GO:0086013//membrane repolarization during cardiac muscle cell action potential;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0035556//intracellular signal transduction;GO:0060306//regulation of membrane repolarization;GO:0006605//protein targeting;GO:0097193//intrinsic apoptotic signaling pathway;GO:1901016//regulation of potassium ion transmembrane transporter activity,GO:0051219//phosphoprotein binding;GO:0046982//protein heterodimerization activity;GO:0044325//ion channel binding;GO:0023026//MHC class II protein complex binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0042826//histone deacetylase binding;GO:0015459//potassium channel regulator activity;GO:0050815//phosphoserine binding;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding,K06630//Pathogenic Escherichia coli infection;Epstein-Barr virus infection;Cell cycle;Neurotrophin signaling pathway;Oocyte meiosis
7532,0,89,1,38,294,0,0,25,85,0,5,0,"YWHAG;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma",GO:0005829//cytosol;GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:0032869//cellular response to insulin stimulus;GO:0048167//regulation of synaptic plasticity;GO:0009966//regulation of signal transduction;GO:0006915//apoptotic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle;GO:0006605//protein targeting;GO:0061024//membrane organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045664//regulation of neuron differentiation;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006469//negative regulation of protein kinase activity,GO:0005080//protein kinase C binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008426//protein kinase C inhibitor activity;GO:0019904//protein domain specific binding;GO:0030971//receptor tyrosine kinase binding,K06630//Pathogenic Escherichia coli infection;Cell cycle;Epstein-Barr virus infection;Oocyte meiosis;Neurotrophin signaling pathway
7533,0,0,0,15,4,0,1,0,0,0,0,0,"YWHAH;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0005829//cytosol;GO:0030659//cytoplasmic vesicle membrane,"GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0086010//membrane depolarization during action potential;GO:0045664//regulation of neuron differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021762//substantia nigra development;GO:0006886//intracellular protein transport;GO:0050774//negative regulation of dendrite morphogenesis;GO:0006915//apoptotic process;GO:0048167//regulation of synaptic plasticity;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0002028//regulation of sodium ion transport;GO:0097193//intrinsic apoptotic signaling pathway;GO:0061024//membrane organization;GO:0006713//glucocorticoid catabolic process;GO:0042921//glucocorticoid receptor signaling pathway",GO:0017080//sodium channel regulator activity;GO:0005159//insulin-like growth factor receptor binding;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0046982//protein heterodimerization activity;GO:0035259//glucocorticoid receptor binding,K06630//Neurotrophin signaling pathway;Oocyte meiosis;Epstein-Barr virus infection;Cell cycle;Pathogenic Escherichia coli infection
7534,0,220,2,284,1225,1,1,0,18,0,15,0,"YWHAZ;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta",GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0043234//protein complex;GO:0042470//melanosome;GO:0030659//cytoplasmic vesicle membrane;GO:0005634//nucleus;GO:0005615//extracellular space;GO:0042629//mast cell granule;GO:0005925//focal adhesion;GO:0005654//nucleoplasm;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0072562//blood microparticle;GO:0031252//cell leading edge;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0002553//histamine secretion by mast cell;GO:0016071//mRNA metabolic process;GO:0030168//platelet activation;GO:0016070//RNA metabolic process;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0042493//response to drug;GO:0061024//membrane organization;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006915//apoptotic process;GO:0007596//blood coagulation;GO:0006626//protein targeting to mitochondrion,GO:0032403//protein complex binding;GO:0019904//protein domain specific binding;GO:0008134//transcription factor binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K06630//Pathogenic Escherichia coli infection;Cell cycle;Epstein-Barr virus infection;Oocyte meiosis;Neurotrophin signaling pathway
7535,1,0,0,0,10,7,20,0,29,0,0,27,ZAP70;zeta-chain (TCR) associated protein kinase 70kDa,GO:0042101//T cell receptor complex;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0001772//immunological synapse;GO:0005911//cell-cell junction,GO:0050852//T cell receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0072678//T cell migration;GO:0043366//beta selection;GO:0070489//T cell aggregation;GO:0046777//protein autophosphorylation;GO:0042113//B cell activation;GO:0050850//positive regulation of calcium-mediated signaling;GO:0045582//positive regulation of T cell differentiation;GO:0035556//intracellular signal transduction;GO:0042110//T cell activation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006955//immune response;GO:0002250//adaptive immune response;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0045059//positive thymic T cell selection;GO:0030217//T cell differentiation;GO:0045060//negative thymic T cell selection,GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0001784//phosphotyrosine binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding,K07360//Primary immunodeficiency;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;NF-kappa B signaling pathway
7536,0,38,1,20,26,0,0,69,51,33,0,0,SF1;splicing factor 1,GO:0005634//nucleus;GO:0005840//ribosome;GO:0005681//spliceosomal complex;GO:0005730//nucleolus,"GO:0050810//regulation of steroid biosynthetic process;GO:0000389//mRNA 3'-splice site recognition;GO:0033327//Leydig cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0030238//male sex determination;GO:0006351//transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0000245//spliceosomal complex assembly",GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding;GO:0003714//transcription corepressor activity,-
7538,0,0,0,0,0,2,21,0,21,0,0,0,ZFP36;ZFP36 ring finger protein,GO:0005829//cytosol;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:1900153//positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0035556//intracellular signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0006402//mRNA catabolic process;GO:0042594//response to starvation;GO:0035278//negative regulation of translation involved in gene silencing by miRNA;GO:0045638//negative regulation of myeloid cell differentiation;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0050728//negative regulation of inflammatory response;GO:0050779//RNA destabilization;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0032680//regulation of tumor necrosis factor production",GO:0019957//C-C chemokine binding;GO:0003729//mRNA binding;GO:0003727//single-stranded RNA binding;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0017091//AU-rich element binding;GO:0071889//14-3-3 protein binding;GO:0046872//metal ion binding;GO:0035925//mRNA 3'-UTR AU-rich region binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K15308//HTLV-I infection
7539,0,0,0,0,0,0,38,0,6,0,0,0,ZFP37;ZFP37 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
754,2,0,0,0,14,14,0,0,11,0,0,0,PTTG1IP;pituitary tumor-transforming 1 interacting protein,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0006606//protein import into nucleus,GO:0004872//receptor activity,-
7541,157,0,1,16,29,39,0,1,13,95,9,0,ZBTB14;zinc finger and BTB domain containing 14,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding,K10500//Cell cycle;Transcriptional misregulation in cancer
7542,0,0,19,0,2,0,0,0,27,0,0,0,ZFPL1;zinc finger protein-like 1,GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,"GO:0016192//vesicle-mediated transport;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7543,57,48,0,74,238,0,40,0,30,87,0,0,"ZFX;zinc finger protein, X-linked",GO:0005634//nucleus,"GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0048872//homeostasis of number of cells;GO:0001541//ovarian follicle development;GO:0035264//multicellular organism growth;GO:0006351//transcription, DNA-templated;GO:0009791//post-embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0048599//oocyte development;GO:0060746//parental behavior;GO:0016265//death",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,-
7544,0,5,0,17,63,0,0,87,0,0,2,0,"ZFY;zinc finger protein, Y-linked",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7545,0,0,0,0,0,5,0,0,31,0,0,0,ZIC1;Zic family member 1,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0042307//positive regulation of protein import into nucleus;GO:0042472//inner ear morphogenesis;GO:0030154//cell differentiation;GO:0021510//spinal cord development;GO:0008589//regulation of smoothened signaling pathway;GO:0007389//pattern specification process;GO:0007628//adult walking behavior;GO:0007420//brain development;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7546,0,0,0,0,0,0,25,0,32,0,0,0,ZIC2;Zic family member 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007420//brain development;GO:0048066//developmental pigmentation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001843//neural tube closure;GO:0007601//visual perception;GO:0031290//retinal ganglion cell axon guidance",GO:0003677//DNA binding;GO:0031490//chromatin DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K06235//Hedgehog signaling pathway
7547,0,0,0,0,0,0,0,0,27,0,12,0,ZIC3;Zic family member 3,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001947//heart looping;GO:0030324//lung development;GO:0006351//transcription, DNA-templated;GO:0071907//determination of digestive tract left/right asymmetry;GO:0071910//determination of liver left/right asymmetry;GO:0030154//cell differentiation;GO:0035469//determination of pancreatic left/right asymmetry;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035545//determination of left/right asymmetry in nervous system;GO:0007368//determination of left/right symmetry",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
7549,0,43,61,42,129,0,0,182,0,0,183,1,ZNF2;zinc finger protein 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
755,0,57,35,1,32,0,0,31,66,0,205,0,C21orf2;chromosome 21 open reading frame 2,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization;GO:0007224//smoothened signaling pathway;GO:0060271//cilium morphogenesis,-,K14284//Herpes simplex infection;RNA transport;mRNA surveillance pathway;Influenza A;Ribosome biogenesis in eukaryotes
7551,69,96,26,128,172,0,4,0,11,0,215,0,ZNF3;zinc finger protein 3,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045321//leukocyte activation;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7552,0,0,0,0,17,11,0,0,27,0,0,0,ZNF711;zinc finger protein 711,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding,-
7553,0,0,0,33,13,0,0,0,25,1,0,0,ZNF7;zinc finger protein 7,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7554,0,0,0,0,8,0,27,0,8,0,0,0,ZNF8;zinc finger protein 8,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030509//BMP signaling pathway;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7555,0,192,39,342,848,0,0,1,36,0,0,0,"CNBP;CCHC-type zinc finger, nucleic acid binding protein",GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol,"GO:0006355//regulation of transcription, DNA-templated;GO:0006695//cholesterol biosynthetic process;GO:0008284//positive regulation of cell proliferation;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003697//single-stranded DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7556,0,0,0,16,11,0,0,0,1,0,3,26,ZNF10;zinc finger protein 10,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
7559,0,0,0,42,35,0,0,0,15,0,0,343,ZNF12;zinc finger protein 12,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7561,0,34,0,16,27,0,0,0,0,0,0,0,ZNF14;zinc finger protein 14,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7562,0,0,0,0,15,0,40,0,5,0,0,0,ZNF708;zinc finger protein 708,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7564,0,0,0,0,7,9,10,0,22,0,0,0,ZNF16;zinc finger protein 16,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045648//positive regulation of erythrocyte differentiation;GO:0043066//negative regulation of apoptotic process;GO:1901989//positive regulation of cell cycle phase transition;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0072707//cellular response to sodium dodecyl sulfate;GO:0051781//positive regulation of cell division;GO:0051301//cell division;GO:0008284//positive regulation of cell proliferation;GO:0033674//positive regulation of kinase activity;GO:0007049//cell cycle;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7565,0,0,0,0,17,26,0,0,39,0,0,0,ZNF17;zinc finger protein 17,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7566,0,0,0,0,4,20,0,0,0,1,3,0,ZNF18;zinc finger protein 18,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7567,0,0,0,11,0,0,63,0,12,0,0,0,ZNF19;zinc finger protein 19,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7569,0,0,0,0,8,6,15,0,51,0,0,0,ZNF182;zinc finger protein 182,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
757,0,23,0,0,1,18,0,24,26,0,1,0,TMEM50B;transmembrane protein 50B,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
7570,0,89,0,6,96,13,0,0,34,2,0,0,ZNF22;zinc finger protein 22,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0042476//odontogenesis",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
7571,76,0,0,0,0,1,0,0,40,0,0,0,ZNF23;zinc finger protein 23,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7572,0,60,3,128,241,17,0,0,26,0,0,0,ZNF24;zinc finger protein 24,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042552//myelination",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,-
7574,0,14,0,12,4,12,9,0,17,0,0,0,ZNF26;zinc finger protein 26,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7576,0,1,0,24,17,16,0,0,31,0,0,0,ZNF28;zinc finger protein 28,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7579,89,0,0,0,21,8,0,0,58,133,0,0,ZSCAN20;zinc finger and SCAN domain containing 20,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
758,0,0,0,0,19,15,0,83,56,0,0,0,MPPED1;metallophosphoesterase domain containing 1,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
7580,0,100,0,27,50,0,0,0,0,0,28,0,ZNF32;zinc finger protein 32,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7581,0,59,0,89,220,13,14,0,16,0,0,0,ZNF33A;zinc finger protein 33A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7582,312,0,0,97,259,0,0,0,69,0,21,0,ZNF33B;zinc finger protein 33B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7584,0,0,0,23,28,0,0,0,14,0,0,0,ZNF35;zinc finger protein 35,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005623//cell,"GO:0071300//cellular response to retinoic acid;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7586,0,134,2,166,455,50,15,0,75,0,6,0,ZKSCAN1;zinc finger with KRAB and SCAN domains 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7587,0,1,4,49,90,3,101,0,102,0,0,0,ZNF37A;zinc finger protein 37A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7589,0,4,1,129,14,0,0,0,0,0,25,1,ZSCAN21;zinc finger and SCAN domain containing 21,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
7592,0,0,0,31,52,47,0,0,9,0,0,0,ZNF41;zinc finger protein 41,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7593,0,28,1,2,19,0,20,292,0,0,87,0,MZF1;myeloid zinc finger 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
7594,0,1,0,6,30,16,0,50,0,97,0,377,ZNF43;zinc finger protein 43,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7596,0,0,1,39,83,0,34,0,68,159,25,0,ZNF45;zinc finger protein 45,GO:0005654//nucleoplasm,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0007275//multicellular organismal development;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7597,0,0,0,0,16,0,0,26,0,0,24,0,ZBTB25;zinc finger and BTB domain containing 25,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
760,0,0,0,0,0,0,0,120,35,0,0,0,CA2;carbonic anhydrase II,GO:0030424//axon;GO:0005615//extracellular space;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0043209//myelin sheath,"GO:0002009//morphogenesis of an epithelium;GO:0045672//positive regulation of osteoclast differentiation;GO:0051453//regulation of intracellular pH;GO:0009268//response to pH;GO:0006730//one-carbon metabolic process;GO:0032849//positive regulation of cellular pH reduction;GO:0001822//kidney development;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0044281//small molecule metabolic process;GO:0046903//secretion;GO:0045780//positive regulation of bone resorption;GO:0044070//regulation of anion transport;GO:0038166//angiotensin-activated signaling pathway;GO:0015701//bicarbonate transport;GO:0043627//response to estrogen;GO:2001150//positive regulation of dipeptide transmembrane transport;GO:0042475//odontogenesis of dentin-containing tooth;GO:0010043//response to zinc ion",GO:0004089//carbonate dehydratase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K01672//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Nitrogen metabolism;Pancreatic secretion;Collecting duct acid secretion
761,1,0,0,0,0,0,0,44,0,0,0,0,"CA3;carbonic anhydrase III, muscle specific",GO:0005829//cytosol,GO:0006979//response to oxidative stress;GO:0045471//response to ethanol;GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process,GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding;GO:0016151//nickel cation binding,K01672//Bile secretion;Nitrogen metabolism;Pancreatic secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Collecting duct acid secretion
762,0,0,0,0,0,13,24,73,13,35,0,0,CA4;carbonic anhydrase IV,GO:0016529//sarcoplasmic reticulum;GO:0030667//secretory granule membrane;GO:0016323//basolateral plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031526//brush border membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0030658//transport vesicle membrane;GO:0042383//sarcolemma;GO:0005791//rough endoplasmic reticulum;GO:0048471//perinuclear region of cytoplasm;GO:0031362//anchored component of external side of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016324//apical plasma membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005802//trans-Golgi network,GO:0048513//organ development;GO:0042493//response to drug;GO:0006730//one-carbon metabolic process;GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport;GO:0048545//response to steroid hormone,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity,K01672//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Pancreatic secretion;Nitrogen metabolism;Collecting duct acid secretion
7620,0,0,0,0,3,0,0,0,0,0,9,0,ZNF69;zinc finger protein 69,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7621,0,35,1,0,20,26,23,0,32,0,0,0,ZNF70;zinc finger protein 70,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7625,111,0,0,0,0,0,0,0,0,0,17,0,ZNF74;zinc finger protein 74,GO:0005730//nucleolus;GO:0015629//actin cytoskeleton;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006351//transcription, DNA-templated",GO:0003723//RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7626,0,24,4,31,43,0,0,0,52,0,0,0,ZNF75D;zinc finger protein 75D,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7629,117,0,31,0,36,5,0,197,46,143,24,0,ZNF76;zinc finger protein 76,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
763,0,0,0,0,0,0,0,0,7,0,0,0,"CA5A;carbonic anhydrase VA, mitochondrial",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0015701//bicarbonate transport;GO:0044281//small molecule metabolic process;GO:0006730//one-carbon metabolic process,GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding,K01672//Collecting duct acid secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Pancreatic secretion;Nitrogen metabolism
7633,0,0,0,0,9,0,0,58,0,0,0,0,ZNF79;zinc finger protein 79,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7634,0,0,0,0,0,0,17,29,51,0,0,0,ZNF80;zinc finger protein 80,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7637,0,0,0,0,0,2,0,1,1,0,0,0,ZNF84;zinc finger protein 84,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7638,0,56,0,0,0,0,0,0,20,0,0,0,ZNF221;zinc finger protein 221,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7639,0,0,1,9,0,37,24,0,23,0,0,0,ZNF85;zinc finger protein 85,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
7643,0,0,0,0,0,0,0,0,22,29,0,0,ZNF90;zinc finger protein 90,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7644,0,0,0,0,16,0,0,0,12,0,0,0,ZNF91;zinc finger protein 91,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7652,0,0,0,0,0,14,122,0,12,0,0,0,ZNF99;zinc finger protein 99,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
766,0,0,0,0,0,0,0,0,0,0,9,0,CA7;carbonic anhydrase VII,GO:0005829//cytosol,"GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0032849//positive regulation of cellular pH reduction;GO:0006730//one-carbon metabolic process",GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding,K01672//Collecting duct acid secretion;Pancreatic secretion;Nitrogen metabolism;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
767,0,0,0,0,7,0,13,0,0,0,0,0,CA8;carbonic anhydrase VIII,GO:0005737//cytoplasm,GO:0048015//phosphatidylinositol-mediated signaling;GO:0006730//one-carbon metabolic process,GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity,K01672//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Nitrogen metabolism;Pancreatic secretion;Bile secretion;Collecting duct acid secretion
7673,97,0,0,0,14,0,0,0,0,0,0,1,ZNF222;zinc finger protein 222,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7675,0,0,0,36,10,0,0,0,0,0,0,0,ZNF121;zinc finger protein 121,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
767583,0,0,0,0,0,0,0,0,19,0,0,0,"SNORD114-7;small nucleolar RNA, C/D box 114-7",-,-,-,-
767585,0,0,0,0,0,33,0,0,0,0,0,0,"SNORD114-9;small nucleolar RNA, C/D box 114-9",-,-,-,-
767595,0,0,0,0,0,0,0,0,9,0,0,0,"SNORD114-17;small nucleolar RNA, C/D box 114-17",-,-,-,-
767605,0,0,0,0,0,0,0,0,11,0,0,0,"SNORD114-25;small nucleolar RNA, C/D box 114-25",-,-,-,-
7678,0,6,0,7,4,0,0,0,34,0,22,0,ZNF124;zinc finger protein 124,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
767811,0,0,0,0,0,0,2,0,1,0,4,0,"H2BFXP;H2B histone family, member X, pseudogene",-,-,-,K11252//Systemic lupus erythematosus;Alcoholism
767846,0,17,23,0,16,0,0,0,0,0,10,0,PFN1P2;profilin 1 pseudogene 2,-,-,-,K05759//Shigellosis;Regulation of actin cytoskeleton;Salmonella infection
768,0,0,0,0,0,0,23,0,0,11,7,0,CA9;carbonic anhydrase IX,GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0031528//microvillus membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0015701//bicarbonate transport;GO:0002009//morphogenesis of an epithelium;GO:0033574//response to testosterone;GO:0071456//cellular response to hypoxia;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0046903//secretion;GO:0044281//small molecule metabolic process;GO:0006730//one-carbon metabolic process;GO:0042493//response to drug,GO:0004089//carbonate dehydratase activity;GO:0008270//zinc ion binding,K01672//Nitrogen metabolism;Pancreatic secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Collecting duct acid secretion
7681,0,0,0,0,0,0,0,0,11,0,0,0,MKRN3;makorin ring finger protein 3,GO:0030529//ribonucleoprotein complex,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity,-
768206,0,0,0,0,0,0,0,0,0,0,4,0,PRCD;progressive rod-cone degeneration,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0007601//visual perception;GO:0050896//response to stimulus,-,-
768211,0,0,0,0,10,0,4,0,16,0,20,0,RELL1;RELT-like 1,GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K05156//Cytokine-cytokine receptor interaction
768215,0,0,0,0,0,0,0,0,3,0,0,0,MIR767;microRNA 767,-,-,-,-
768217,0,0,0,0,0,0,29,0,0,0,0,0,MIR769;microRNA 769,-,-,-,-
768218,0,0,0,0,0,0,8,0,0,0,0,0,MIR766;microRNA 766,-,-,-,-
768239,0,0,0,0,0,0,0,0,11,0,0,0,PSAPL1;prosaposin-like 1 (gene/pseudogene),GO:0005576//extracellular region;GO:0005764//lysosome,GO:0006665//sphingolipid metabolic process,-,K12382//Lysosome
7690,0,0,0,0,1,0,0,164,7,0,0,0,ZNF131;zinc finger protein 131,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,K10500//Cell cycle;Transcriptional misregulation in cancer
7691,0,0,0,13,50,0,0,0,25,0,29,0,ZNF132;zinc finger protein 132,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7692,0,0,37,16,28,0,0,46,26,0,0,0,ZNF133;zinc finger protein 133,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7693,0,15,0,3,18,18,56,0,0,0,0,0,ZNF134;zinc finger protein 134,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7694,0,0,0,0,6,17,14,0,59,0,0,0,ZNF135;zinc finger protein 135,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7695,0,63,0,10,97,9,55,104,0,0,0,0,ZNF136;zinc finger protein 136,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
7696,0,0,0,0,0,0,0,0,28,0,1,0,"ZNF137P;zinc finger protein 137, pseudogene",-,-,-,-
7697,0,0,0,0,0,0,2,0,21,0,0,0,ZNF138;zinc finger protein 138,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K01008//Metabolic pathways;Selenocompound metabolism
770,0,0,0,0,0,3,0,0,0,0,2,0,CA11;carbonic anhydrase XI,GO:0005576//extracellular region;GO:0016323//basolateral plasma membrane,-,GO:0004089//carbonate dehydratase activity,K01672//Collecting duct acid secretion;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Pancreatic secretion;Nitrogen metabolism
7700,110,0,0,2,0,0,0,0,0,0,0,0,ZNF141;zinc finger protein 141,GO:0005634//nucleus,"GO:0006366//transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0035108//limb morphogenesis",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7701,0,0,0,5,52,0,19,0,16,0,3,0,ZNF142;zinc finger protein 142,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7702,87,1,0,19,22,25,0,1,45,0,10,0,ZNF143;zinc finger protein 143,GO:0005654//nucleoplasm,GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006359//regulation of transcription from RNA polymerase III promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7703,0,184,203,133,317,0,39,94,72,0,247,0,PCGF2;polycomb group ring finger 2,GO:0016604//nuclear body;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0001739//sex chromatin;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex,"GO:0016573//histone acetylation;GO:0009952//anterior/posterior pattern specification;GO:0001701//in utero embryonic development;GO:0006351//transcription, DNA-templated;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0048704//embryonic skeletal system morphogenesis;GO:0016567//protein ubiquitination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
7704,19,36,20,5,61,38,0,0,0,0,79,0,ZBTB16;zinc finger and BTB domain containing 16,GO:0005886//plasma membrane;GO:0016605//PML body;GO:0017053//transcriptional repressor complex;GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0005634//nucleus;GO:0016604//nuclear body,"GO:0045778//positive regulation of ossification;GO:0043065//positive regulation of apoptotic process;GO:0034504//protein localization to nucleus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030097//hemopoiesis;GO:0006915//apoptotic process;GO:0035136//forelimb morphogenesis;GO:0030099//myeloid cell differentiation;GO:0061036//positive regulation of cartilage development;GO:0045600//positive regulation of fat cell differentiation;GO:0051138//positive regulation of NK T cell differentiation;GO:0009952//anterior/posterior pattern specification;GO:0048133//male germ-line stem cell asymmetric division;GO:0007417//central nervous system development;GO:0016567//protein ubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0009880//embryonic pattern specification;GO:0006351//transcription, DNA-templated;GO:0001823//mesonephros development;GO:0042733//embryonic digit morphogenesis;GO:0032332//positive regulation of chondrocyte differentiation;GO:0051216//cartilage development;GO:0035116//embryonic hindlimb morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045638//negative regulation of myeloid cell differentiation",GO:0019904//protein domain specific binding;GO:0042802//identical protein binding;GO:0003677//DNA binding;GO:0003690//double-stranded DNA binding;GO:0008022//protein C-terminus binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K10055//Acute myeloid leukemia;Pathways in cancer;Transcriptional misregulation in cancer
7705,0,84,24,40,134,0,15,1,19,0,0,0,ZNF146;zinc finger protein 146,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008201//heparin binding,-
7706,129,1,0,20,73,23,0,0,40,0,0,0,TRIM25;tripartite motif containing 25,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0033280//response to vitamin D;GO:0032480//negative regulation of type I interferon production;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0043627//response to estrogen;GO:1902187//negative regulation of viral release from host cell;GO:0046597//negative regulation of viral entry into host cell;GO:1902186//regulation of viral release from host cell;GO:0046596//regulation of viral entry into host cell,GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity,K10652//RIG-I-like receptor signaling pathway;Influenza A;NF-kappa B signaling pathway
7707,0,48,0,57,165,61,7,0,8,0,0,0,ZNF148;zinc finger protein 148,GO:0005634//nucleus,"GO:0021762//substantia nigra development;GO:0006461//protein complex assembly;GO:0010629//negative regulation of gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006968//cellular defense response;GO:0007276//gamete generation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated",GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003690//double-stranded DNA binding,-
7709,0,0,0,0,0,16,0,0,22,129,0,0,ZBTB17;zinc finger and BTB domain containing 17,GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045786//negative regulation of cell cycle;GO:0001702//gastrulation with mouth forming second;GO:0007398//ectoderm development;GO:0030968//endoplasmic reticulum unfolded protein response",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K10500//Cell cycle;Transcriptional misregulation in cancer
771,1,0,0,0,0,8,34,0,19,0,11,0,CA12;carbonic anhydrase XII,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0044281//small molecule metabolic process;GO:0015701//bicarbonate transport;GO:0006730//one-carbon metabolic process,GO:0008270//zinc ion binding;GO:0004089//carbonate dehydratase activity,K01672//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Nitrogen metabolism;Pancreatic secretion;Bile secretion;Collecting duct acid secretion
7710,0,17,0,0,0,13,71,0,102,0,0,0,ZNF154;zinc finger protein 154,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7711,0,31,44,10,22,21,17,0,14,0,49,0,ZNF155;zinc finger protein 155,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7712,0,0,0,0,0,0,25,0,24,0,0,0,ZNF157;zinc finger protein 157,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7716,0,1,0,60,49,13,2,0,28,0,0,0,VEZF1;vascular endothelial zinc finger 1,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001525//angiogenesis;GO:0001885//endothelial cell development;GO:0006366//transcription from RNA polymerase II promoter;GO:0006968//cellular defense response,GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7718,0,65,0,26,61,0,19,49,2,0,24,0,ZNF165;zinc finger protein 165,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
7726,0,0,0,0,0,0,0,0,2,0,0,0,TRIM26;tripartite motif containing 26,GO:0005737//cytoplasm,GO:1902187//negative regulation of viral release from host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0045087//innate immune response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity,GO:0046872//metal ion binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
7727,0,0,0,0,0,12,37,0,29,131,0,0,ZNF174;zinc finger protein 174,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005730//nucleolus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding,-
7728,0,0,0,0,0,0,0,0,38,0,0,0,ZNF175;zinc finger protein 175,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0045111//intermediate filament cytoskeleton;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051607//defense response to virus",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
773,0,0,0,0,0,38,32,6,96,0,19,142,"CACNA1A;calcium channel, voltage-dependent, P/Q type, alpha 1A subunit",GO:0005891//voltage-gated calcium channel complex;GO:0005634//nucleus;GO:0042995//cell projection;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030425//dendrite,"GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0086010//membrane depolarization during action potential;GO:0016049//cell growth;GO:0043113//receptor clustering;GO:0021679//cerebellar molecular layer development;GO:0019226//transmission of nerve impulse;GO:0048813//dendrite morphogenesis;GO:0017156//calcium ion-dependent exocytosis;GO:0021522//spinal cord motor neuron differentiation;GO:0021750//vestibular nucleus development;GO:0021702//cerebellar Purkinje cell differentiation;GO:0014051//gamma-aminobutyric acid secretion;GO:0050770//regulation of axonogenesis;GO:0014056//regulation of acetylcholine secretion, neurotransmission;GO:0048266//behavioral response to pain;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0051899//membrane depolarization;GO:0043524//negative regulation of neuron apoptotic process;GO:0007416//synapse assembly;GO:0042445//hormone metabolic process;GO:0007274//neuromuscular synaptic transmission;GO:0021590//cerebellum maturation;GO:0006112//energy reserve metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0050883//musculoskeletal movement, spinal reflex action;GO:0070588//calcium ion transmembrane transport;GO:0032353//negative regulation of hormone biosynthetic process;GO:0070509//calcium ion import;GO:0030644//cellular chloride ion homeostasis;GO:0008219//cell death;GO:0044281//small molecule metabolic process;GO:0035249//synaptic transmission, glutamatergic;GO:0050796//regulation of insulin secretion;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0050885//neuromuscular process controlling balance;GO:0007628//adult walking behavior;GO:0060024//rhythmic synaptic transmission;GO:0048791//calcium ion-dependent exocytosis of neurotransmitter;GO:0006006//glucose metabolic process;GO:0042133//neurotransmitter metabolic process;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission",GO:0008331//high voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0019905//syntaxin binding,K04344//GABAergic synapse;Dopaminergic synapse;Long-term depression;Cholinergic synapse;Nicotine addiction;Serotonergic synapse;Calcium signaling pathway;Retrograde endocannabinoid signaling;Synaptic vesicle cycle;MAPK signaling pathway;Glutamatergic synapse;Taste transduction;Morphine addiction;Type II diabetes mellitus
7732,0,0,0,0,0,27,31,0,38,0,1,0,RNF112;ring finger protein 112,GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006184//GTP catabolic process,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0008270//zinc ion binding,-
7733,0,0,0,2,6,0,0,0,33,47,12,0,ZNF180;zinc finger protein 180,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7737,47,0,0,23,0,0,0,0,0,0,56,0,RNF113A;ring finger protein 113A,-,-,GO:0005515//protein binding;GO:0008270//zinc ion binding,-
7738,0,18,0,0,14,5,0,0,23,0,9,0,ZNF184;zinc finger protein 184,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
7739,78,12,0,1,6,12,13,111,40,0,1,0,ZNF185;zinc finger protein 185 (LIM domain),GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding,K06084//Adherens junction
774,310,0,3,0,0,44,27,133,120,155,0,0,"CACNA1B;calcium channel, voltage-dependent, N type, alpha 1B subunit",GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0043025//neuronal cell body;GO:0005891//voltage-gated calcium channel complex,GO:0070588//calcium ion transmembrane transport;GO:0051924//regulation of calcium ion transport;GO:0007269//neurotransmitter secretion;GO:0048265//response to pain;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006810//transport;GO:0008016//regulation of heart contraction;GO:0008217//regulation of blood pressure;GO:0007626//locomotory behavior;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0051899//membrane depolarization,GO:0008022//protein C-terminus binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity;GO:0008331//high voltage-gated calcium channel activity;GO:0005509//calcium ion binding,K04849//Serotonergic synapse;Retrograde endocannabinoid signaling;Calcium signaling pathway;Synaptic vesicle cycle;Nicotine addiction;Cholinergic synapse;Dopaminergic synapse;GABAergic synapse;Type II diabetes mellitus;Morphine addiction;MAPK signaling pathway;Taste transduction
7741,0,0,0,30,0,26,0,0,11,0,1,0,ZSCAN26;zinc finger and SCAN domain containing 26,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
7743,0,0,0,31,9,0,20,0,1,0,25,0,ZNF189;zinc finger protein 189,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
7745,47,1,0,17,67,25,2,51,59,0,18,0,ZKSCAN8;zinc finger with KRAB and SCAN domains 8,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7746,0,0,0,0,10,0,0,0,0,0,0,0,ZSCAN9;zinc finger and SCAN domain containing 9,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7748,0,0,1,0,25,29,49,0,7,0,0,0,ZNF195;zinc finger protein 195,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
775,147,0,2,0,22,24,85,130,119,111,10,0,"CACNA1C;calcium channel, voltage-dependent, L type, alpha 1C subunit",GO:0014069//postsynaptic density;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0005891//voltage-gated calcium channel complex;GO:0002095//caveolar macromolecular signaling complex,GO:0008217//regulation of blood pressure;GO:0006112//energy reserve metabolic process;GO:0046620//regulation of organ growth;GO:0007268//synaptic transmission;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0034765//regulation of ion transmembrane transport;GO:0035585//calcium-mediated signaling using extracellular calcium source;GO:0060402//calcium ion transport into cytosol;GO:0070588//calcium ion transmembrane transport;GO:0019229//regulation of vasoconstriction;GO:0008542//visual learning;GO:0030073//insulin secretion;GO:0030252//growth hormone secretion;GO:0050796//regulation of insulin secretion;GO:0017156//calcium ion-dependent exocytosis;GO:0007411//axon guidance;GO:0086064//cell communication by electrical coupling involved in cardiac conduction;GO:0007628//adult walking behavior;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0060083//smooth muscle contraction involved in micturition;GO:0042593//glucose homeostasis;GO:0044281//small molecule metabolic process,GO:0005516//calmodulin binding;GO:0008331//high voltage-gated calcium channel activity;GO:0051393//alpha-actinin binding;GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K04850//Long-term potentiation;Serotonergic synapse;Dopaminergic synapse;Arrhythmogenic right ventricular cardiomyopathy (ARVC);GnRH signaling pathway;Type II diabetes mellitus;Vascular smooth muscle contraction;MAPK signaling pathway;Glutamatergic synapse;Amphetamine addiction;Cardiac muscle contraction;Dilated cardiomyopathy;Calcium signaling pathway;Retrograde endocannabinoid signaling;Cholinergic synapse;GABAergic synapse;Alzheimer's disease;Hypertrophic cardiomyopathy (HCM)
7750,0,34,0,48,330,18,0,0,53,0,0,0,"ZMYM2;zinc finger, MYM-type 2",GO:0005829//cytosol;GO:0016605//PML body,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0031624//ubiquitin conjugating enzyme binding,-
7752,0,2,0,0,0,0,0,0,9,0,0,0,ZNF200;zinc finger protein 200,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003676//nucleic acid binding;GO:0046872//metal ion binding,-
7754,0,1,0,17,31,0,0,0,0,0,0,0,"ZNF204P;zinc finger protein 204, pseudogene",-,-,-,-
7755,75,32,0,18,12,22,22,0,27,99,61,1,ZNF205;zinc finger protein 205,GO:0005634//nucleus,"GO:0010729//positive regulation of hydrogen peroxide biosynthetic process;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
7756,0,43,0,3,79,11,0,0,0,0,0,0,ZNF207;zinc finger protein 207,GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005874//microtubule;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0050821//protein stabilization;GO:0007094//mitotic spindle assembly checkpoint;GO:0000070//mitotic sister chromatid segregation;GO:0051983//regulation of chromosome segregation",GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008201//heparin binding;GO:0008017//microtubule binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
7757,0,0,0,0,12,20,3,28,66,0,0,0,ZNF208;zinc finger protein 208,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
776,0,65,41,0,13,27,56,1,80,0,21,0,"CACNA1D;calcium channel, voltage-dependent, L type, alpha 1D subunit",GO:0005891//voltage-gated calcium channel complex;GO:0030018//Z disc;GO:0005886//plasma membrane,GO:0050796//regulation of insulin secretion;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0051928//positive regulation of calcium ion transport;GO:0007411//axon guidance;GO:0006816//calcium ion transport;GO:0086012//membrane depolarization during cardiac muscle cell action potential;GO:0086046//membrane depolarization during SA node cell action potential;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0007605//sensory perception of sound;GO:0044281//small molecule metabolic process;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0060372//regulation of atrial cardiac muscle cell membrane repolarization;GO:1901379//regulation of potassium ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0086091//regulation of heart rate by cardiac conduction;GO:0086052//membrane repolarization during SA node cell action potential,GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity;GO:0051393//alpha-actinin binding;GO:0030506//ankyrin binding;GO:0008331//high voltage-gated calcium channel activity;GO:0086059//voltage-gated calcium channel activity involved SA node cell action potential,K04851//Hypertrophic cardiomyopathy (HCM);Alzheimer's disease;Calcium signaling pathway;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Cardiac muscle contraction;GABAergic synapse;Cholinergic synapse;Type II diabetes mellitus;MAPK signaling pathway;Amphetamine addiction;Glutamatergic synapse;Vascular smooth muscle contraction;Serotonergic synapse;Carbohydrate digestion and absorption;Dopaminergic synapse;Arrhythmogenic right ventricular cardiomyopathy (ARVC);GnRH signaling pathway
7760,0,0,0,0,0,0,0,0,11,0,0,0,ZNF213;zinc finger protein 213,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7761,0,0,0,11,0,76,0,0,20,0,0,0,ZNF214;zinc finger protein 214,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7762,0,23,63,20,16,0,0,4,180,0,10,346,ZNF215;zinc finger protein 215,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
7763,0,0,0,27,17,0,0,0,34,0,10,0,"ZFAND5;zinc finger, AN1-type domain 5",GO:0005737//cytoplasm,GO:0048745//smooth muscle tissue development;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0001944//vasculature development;GO:0060324//face development;GO:0001701//in utero embryonic development;GO:0048705//skeletal system morphogenesis;GO:0003016//respiratory system process;GO:0010761//fibroblast migration,GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
7764,100,105,0,52,241,6,0,160,21,1,9,0,ZNF217;zinc finger protein 217,GO:0005654//nucleoplasm;GO:0000118//histone deacetylase complex,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7766,0,0,0,1,15,0,0,0,0,0,0,0,ZNF223;zinc finger protein 223,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7767,39,7,0,34,93,0,0,0,10,0,35,0,ZNF224;zinc finger protein 224,GO:0017053//transcriptional repressor complex;GO:0031965//nuclear membrane;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7768,0,0,0,0,10,0,0,0,23,0,0,0,ZNF225;zinc finger protein 225,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7769,1,0,0,20,21,13,0,0,0,0,0,0,ZNF226;zinc finger protein 226,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
777,50,0,0,0,0,43,44,129,85,115,15,93,"CACNA1E;calcium channel, voltage-dependent, R type, alpha 1E subunit",GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex,GO:0006810//transport;GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0051899//membrane depolarization;GO:0044281//small molecule metabolic process,GO:0005509//calcium ion binding;GO:0008331//high voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity,K04852//MAPK signaling pathway;Calcium signaling pathway;Type II diabetes mellitus
7770,45,2,2,101,120,22,33,0,31,0,71,0,ZNF227;zinc finger protein 227,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7771,0,17,0,0,34,0,0,0,27,0,0,0,ZNF112;zinc finger protein 112,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7772,0,1,0,0,26,0,21,0,61,0,14,0,ZNF229;zinc finger protein 229,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7773,0,0,0,0,0,0,0,0,51,0,0,0,ZNF230;zinc finger protein 230,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
7775,0,37,42,62,11,0,19,413,46,0,108,0,ZNF232;zinc finger protein 232,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7776,65,0,0,0,17,23,26,0,87,0,0,1,ZNF236;zinc finger protein 236,GO:0005634//nucleus,"GO:0071333//cellular response to glucose stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
7779,0,0,0,8,0,0,0,0,23,0,17,0,"SLC30A1;solute carrier family 30 (zinc transporter), member 1",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0005737//cytoplasm;GO:0031965//nuclear membrane,GO:0006882//cellular zinc ion homeostasis;GO:0070574//cadmium ion transmembrane transport;GO:0046929//negative regulation of neurotransmitter secretion;GO:0001701//in utero embryonic development;GO:0071585//detoxification of cadmium ion;GO:0070509//calcium ion import;GO:0006874//cellular calcium ion homeostasis;GO:0055085//transmembrane transport;GO:0090281//negative regulation of calcium ion import;GO:0006829//zinc ion transport;GO:0071577//zinc ion transmembrane transport;GO:0071584//negative regulation of zinc ion transmembrane import,GO:0005515//protein binding;GO:0019855//calcium channel inhibitor activity;GO:0005385//zinc ion transmembrane transporter activity,K14688//Mineral absorption
778,242,0,0,0,0,26,20,150,71,81,9,0,"CACNA1F;calcium channel, voltage-dependent, L type, alpha 1F subunit",GO:0001750//photoreceptor outer segment;GO:0005891//voltage-gated calcium channel complex;GO:0016021//integral component of membrane;GO:0043204//perikaryon,GO:0048813//dendrite morphogenesis;GO:0050908//detection of light stimulus involved in visual perception;GO:0034765//regulation of ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:0006874//cellular calcium ion homeostasis;GO:0060041//retina development in camera-type eye;GO:0007601//visual perception;GO:0007409//axonogenesis,GO:0008331//high voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding,K04853//Cardiac muscle contraction;Serotonergic synapse;Dilated cardiomyopathy;Retrograde endocannabinoid signaling;Calcium signaling pathway;Cholinergic synapse;GnRH signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);GABAergic synapse;Vascular smooth muscle contraction;Alzheimer's disease;MAPK signaling pathway;Hypertrophic cardiomyopathy (HCM)
7780,88,4,0,0,0,16,43,0,0,0,0,0,"SLC30A2;solute carrier family 30 (zinc transporter), member 2",GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane,GO:0061090//positive regulation of sequestering of zinc ion;GO:0055085//transmembrane transport;GO:0006829//zinc ion transport,GO:0008324//cation transmembrane transporter activity,-
7781,0,0,0,0,0,0,0,0,32,0,0,0,"SLC30A3;solute carrier family 30 (zinc transporter), member 3",GO:0005887//integral component of plasma membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0043005//neuron projection;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0005768//endosome;GO:0005737//cytoplasm,GO:0071577//zinc ion transmembrane transport;GO:0006810//transport;GO:0055085//transmembrane transport;GO:0061088//regulation of sequestering of zinc ion;GO:0051050//positive regulation of transport,GO:0015633//zinc transporting ATPase activity,-
7782,1,2277,623,3188,4097,28,30,606,121,1,1608,636,"SLC30A4;solute carrier family 30 (zinc transporter), member 4",GO:0005737//cytoplasm;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0005770//late endosome,GO:0055069//zinc ion homeostasis;GO:0071577//zinc ion transmembrane transport;GO:0061088//regulation of sequestering of zinc ion;GO:0009636//response to toxic substance,GO:0005385//zinc ion transmembrane transporter activity,-
7783,0,0,0,0,0,11,0,0,14,0,10,0,ZP2;zona pellucida glycoprotein 2 (sperm receptor),GO:0031012//extracellular matrix;GO:0005771//multivesicular body;GO:0030141//secretory granule;GO:0005578//proteinaceous extracellular matrix;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0006828//manganese ion transport;GO:0060468//prevention of polyspermy;GO:0060046//regulation of acrosome reaction;GO:0032504//multicellular organism reproduction;GO:0006886//intracellular protein transport;GO:0007165//signal transduction;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida,GO:0015026//coreceptor activity;GO:0032190//acrosin binding,K13912//Salivary secretion
7784,53,0,0,0,0,0,0,0,57,0,0,0,ZP3;zona pellucida glycoprotein 3 (sperm receptor),GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0031012//extracellular matrix;GO:0002081//outer acrosomal membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005771//multivesicular body;GO:0001669//acrosomal vesicle;GO:0030141//secretory granule;GO:0005615//extracellular space,"GO:0071421//manganese ion transmembrane transport;GO:0045892//negative regulation of transcription, DNA-templated;GO:0090280//positive regulation of calcium ion import;GO:2000386//positive regulation of ovarian follicle development;GO:0010513//positive regulation of phosphatidylinositol biosynthetic process;GO:2000360//negative regulation of binding of sperm to zona pellucida;GO:0035803//egg coat formation;GO:0042102//positive regulation of T cell proliferation;GO:0045860//positive regulation of protein kinase activity;GO:0002922//positive regulation of humoral immune response;GO:2000344//positive regulation of acrosome reaction;GO:0070528//protein kinase C signaling;GO:0032504//multicellular organism reproduction;GO:2000388//positive regulation of antral ovarian follicle growth;GO:0002455//humoral immune response mediated by circulating immunoglobulin;GO:0006828//manganese ion transport;GO:0032729//positive regulation of interferon-gamma production;GO:0001809//positive regulation of type IV hypersensitivity;GO:0032753//positive regulation of interleukin-4 production;GO:0045893//positive regulation of transcription, DNA-templated;GO:0050729//positive regulation of inflammatory response;GO:0070588//calcium ion transmembrane transport;GO:0006886//intracellular protein transport;GO:0007338//single fertilization;GO:0035556//intracellular signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0051897//positive regulation of protein kinase B signaling;GO:0007339//binding of sperm to zona pellucida;GO:0001825//blastocyst formation;GO:2000368//positive regulation of acrosomal vesicle exocytosis;GO:0048599//oocyte development;GO:0002687//positive regulation of leukocyte migration",GO:0032190//acrosin binding;GO:0015279//store-operated calcium channel activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0005384//manganese ion transmembrane transporter activity;GO:0030246//carbohydrate binding,K13912//Salivary secretion
7786,22,214,259,372,665,0,9,71,65,0,174,0,MAP3K12;mitogen-activated protein kinase kinase kinase 12,GO:0005737//cytoplasm;GO:0030426//growth cone;GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030424//axon,GO:0018105//peptidyl-serine phosphorylation;GO:0007254//JNK cascade;GO:0016572//histone phosphorylation;GO:0046777//protein autophosphorylation;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0018107//peptidyl-threonine phosphorylation;GO:0000186//activation of MAPKK activity,GO:0004672//protein kinase activity;GO:0042803//protein homodimerization activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding,K04423//MAPK signaling pathway
7789,0,0,0,19,14,0,0,0,17,46,10,0,"ZXDA;zinc finger, X-linked, duplicated A",GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0070742//C2H2 zinc finger domain binding;GO:0003676//nucleic acid binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
779,98,0,0,0,0,39,32,0,71,0,10,23,"CACNA1S;calcium channel, voltage-dependent, L type, alpha 1S subunit",GO:0016529//sarcoplasmic reticulum;GO:0005886//plasma membrane;GO:0030315//T-tubule;GO:0005737//cytoplasm;GO:0005891//voltage-gated calcium channel complex;GO:0031674//I band,GO:0001501//skeletal system development;GO:0007029//endoplasmic reticulum organization;GO:0007520//myoblast fusion;GO:0034765//regulation of ion transmembrane transport;GO:0043501//skeletal muscle adaptation;GO:0006816//calcium ion transport;GO:0007411//axon guidance;GO:0070588//calcium ion transmembrane transport;GO:0006936//muscle contraction;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0006941//striated muscle contraction;GO:0002074//extraocular skeletal muscle development;GO:0048741//skeletal muscle fiber development;GO:0007528//neuromuscular junction development,GO:0008331//high voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding,K04857//GABAergic synapse;Arrhythmogenic right ventricular cardiomyopathy (ARVC);GnRH signaling pathway;Cholinergic synapse;Calcium signaling pathway;Dilated cardiomyopathy;Serotonergic synapse;Retrograde endocannabinoid signaling;Cardiac muscle contraction;MAPK signaling pathway;Hypertrophic cardiomyopathy (HCM);Alzheimer's disease;Vascular smooth muscle contraction
7791,0,0,0,0,0,0,18,0,0,0,0,0,ZYX;zyxin,GO:0005886//plasma membrane;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0001725//stress fiber;GO:0005913//cell-cell adherens junction;GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0050727//regulation of inflammatory response;GO:0043149//stress fiber assembly;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0016032//viral process,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K06273//Focal adhesion
7798,1,0,0,0,26,39,0,140,99,0,0,0,LUZP1;leucine zipper protein 1,GO:0016020//membrane;GO:0005634//nucleus,GO:0060840//artery development;GO:0021503//neural fold bending;GO:0003281//ventricular septum development,-,-
7799,0,10,0,43,86,0,0,0,0,0,13,0,"PRDM2;PR domain containing 2, with ZNF domain",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0006351//transcription, DNA-templated",GO:0018024//histone-lysine N-methyltransferase activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
7802,0,19,0,0,57,0,0,0,0,0,0,0,"DNALI1;dynein, axonemal, light intermediate chain 1",GO:0005737//cytoplasm;GO:0005930//axoneme;GO:0030175//filopodium;GO:0005858//axonemal dynein complex,GO:0006928//cellular component movement;GO:0008152//metabolic process;GO:0007338//single fertilization,GO:0003777//microtubule motor activity;GO:0005515//protein binding,K10410//Huntington's disease
7803,0,0,115,99,253,0,107,0,46,0,53,0,"PTP4A1;protein tyrosine phosphatase type IVA, member 1",GO:0005819//spindle;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0009898//cytoplasmic side of plasma membrane;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0007275//multicellular organismal development;GO:0030335//positive regulation of cell migration;GO:0007049//cell cycle,GO:0004725//protein tyrosine phosphatase activity,-
7804,216,75,48,13,15,47,0,147,41,0,29,0,"LRP8;low density lipoprotein receptor-related protein 8, apolipoprotein e receptor",GO:0043025//neuronal cell body;GO:0014069//postsynaptic density;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005901//caveola;GO:0043235//receptor complex;GO:0005875//microtubule associated complex,"GO:1900006//positive regulation of dendrite development;GO:0021819//layer formation in cerebral cortex;GO:0021541//ammon gyrus development;GO:0038026//reelin-mediated signaling pathway;GO:0006897//endocytosis;GO:0007596//blood coagulation;GO:0006898//receptor-mediated endocytosis;GO:0071363//cellular response to growth factor stimulus;GO:0006508//proteolysis;GO:0019221//cytokine-mediated signaling pathway;GO:0032793//positive regulation of CREB transcription factor activity;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0007165//signal transduction;GO:0050804//regulation of synaptic transmission;GO:0007603//phototransduction, visible light;GO:0071397//cellular response to cholesterol;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042493//response to drug;GO:0001523//retinoid metabolic process;GO:0006629//lipid metabolic process;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation",GO:0008035//high-density lipoprotein particle binding;GO:0004888//transmembrane signaling receptor activity;GO:0038025//reelin receptor activity;GO:0034185//apolipoprotein binding;GO:0005515//protein binding;GO:0019894//kinesin binding;GO:0005509//calcium ion binding;GO:0030229//very-low-density lipoprotein particle receptor activity,K12473//Bile secretion;Toxoplasmosis;Hepatitis C;Endocytosis
780776,0,162,52,132,445,0,16,95,29,0,445,0,TVP23A;trans-golgi network vesicle protein 23 homolog A (S. cerevisiae),GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
7809,0,0,0,0,0,8,0,0,36,0,0,0,BSND;barttin CLCNK-type chloride channel accessory beta subunit,GO:0005886//plasma membrane;GO:0016323//basolateral plasma membrane;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0034220//ion transmembrane transport;GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity;GO:0017081//chloride channel regulator activity,-
781,0,0,0,15,33,0,0,0,68,0,0,0,"CACNA2D1;calcium channel, voltage-dependent, alpha 2/delta subunit 1",GO:0070062//extracellular vesicular exosome;GO:0016529//sarcoplasmic reticulum;GO:0030315//T-tubule;GO:0005891//voltage-gated calcium channel complex,GO:0070588//calcium ion transmembrane transport;GO:0006816//calcium ion transport;GO:0051924//regulation of calcium ion transport;GO:0034765//regulation of ion transmembrane transport,GO:0046872//metal ion binding;GO:0005245//voltage-gated calcium channel activity,K04858//Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Cardiac muscle contraction;Dilated cardiomyopathy
7812,128,437,2,448,1130,13,0,61,21,0,0,0,"CSDE1;cold shock domain containing E1, RNA-binding",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070937//CRD-mediated mRNA stability complex;GO:0005737//cytoplasm,"GO:0070966//nuclear-transcribed mRNA catabolic process, no-go decay;GO:0006355//regulation of transcription, DNA-templated;GO:0008584//male gonad development",GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,K01490//Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
7813,82,2,1,23,0,30,41,29,64,0,6,0,EVI5;ecotropic viral integration site 5,GO:0005815//microtubule organizing center;GO:0005819//spindle;GO:0005634//nucleus;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005794//Golgi apparatus,"GO:0042147//retrograde transport, endosome to Golgi;GO:0007049//cell cycle;GO:0051301//cell division;GO:0033126//positive regulation of GTP catabolic process;GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation",GO:0017137//Rab GTPase binding;GO:0005097//Rab GTPase activator activity;GO:0005515//protein binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
7818,0,0,47,47,63,0,38,72,5,0,0,0,DAP3;death associated protein 3,GO:0005739//mitochondrion;GO:0015935//small ribosomal subunit;GO:0005730//nucleolus;GO:0005761//mitochondrial ribosome;GO:0005634//nucleus,GO:0097190//apoptotic signaling pathway;GO:0008637//apoptotic mitochondrial changes,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
782,0,0,0,0,0,0,12,47,22,2,7,0,"CACNB1;calcium channel, voltage-dependent, beta 1 subunit",GO:0005891//voltage-gated calcium channel complex;GO:0030315//T-tubule;GO:0016529//sarcoplasmic reticulum,GO:0006810//transport;GO:0007411//axon guidance;GO:0034765//regulation of ion transmembrane transport;GO:0006612//protein targeting to membrane;GO:0070588//calcium ion transmembrane transport,GO:0008331//high voltage-gated calcium channel activity;GO:0005245//voltage-gated calcium channel activity,K04862//Dilated cardiomyopathy;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);MAPK signaling pathway;Hypertrophic cardiomyopathy (HCM)
7827,0,0,0,0,0,0,0,0,15,0,0,0,"NPHS2;nephrosis 2, idiopathic, steroid-resistant (podocin)",GO:0005887//integral component of plasma membrane;GO:0005911//cell-cell junction;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0043234//protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0036057//slit diaphragm;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft,GO:0072249//metanephric glomerular visceral epithelial cell development;GO:0007588//excretion;GO:0031532//actin cytoskeleton reorganization,GO:0005515//protein binding,K03364//Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle
783,0,0,0,0,18,31,0,4,14,18,3,488,"CACNB2;calcium channel, voltage-dependent, beta 2 subunit",GO:0005887//integral component of plasma membrane;GO:0005891//voltage-gated calcium channel complex;GO:0042383//sarcolemma,GO:0070588//calcium ion transmembrane transport;GO:0007411//axon guidance;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006810//transport;GO:0051928//positive regulation of calcium ion transport;GO:0007528//neuromuscular junction development;GO:0007601//visual perception;GO:0070509//calcium ion import,GO:0005262//calcium channel activity;GO:0008331//high voltage-gated calcium channel activity;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity,K04863//Dilated cardiomyopathy;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
7832,0,0,0,3,29,16,35,0,10,0,3,0,"BTG2;BTG family, member 2",GO:0070062//extracellular vesicular exosome,"GO:2000178//negative regulation of neural precursor cell proliferation;GO:0006351//transcription, DNA-templated;GO:0051602//response to electrical stimulus;GO:0008285//negative regulation of cell proliferation;GO:0008306//associative learning;GO:0035914//skeletal muscle cell differentiation;GO:0031175//neuron projection development;GO:0009612//response to mechanical stimulus;GO:0060213//positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0006479//protein methylation;GO:0043434//response to peptide hormone;GO:0006974//cellular response to DNA damage stimulus;GO:0009952//anterior/posterior pattern specification;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0014070//response to organic cyclic compound;GO:0043524//negative regulation of neuron apoptotic process;GO:0021542//dentate gyrus development;GO:0021954//central nervous system neuron development;GO:0017148//negative regulation of translation;GO:0006281//DNA repair",GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K14443//RNA degradation
7837,0,160,0,15,16,0,18,193,21,1,84,0,PXDN;peroxidasin homolog (Drosophila),GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0030198//extracellular matrix organization;GO:0042744//hydrogen peroxide catabolic process;GO:0055114//oxidation-reduction process;GO:0006955//immune response,GO:0005152//interleukin-1 receptor antagonist activity;GO:0020037//heme binding;GO:0004601//peroxidase activity;GO:0046872//metal ion binding;GO:0005201//extracellular matrix structural constituent,K00431//Cytokine-cytokine receptor interaction;Hematopoietic cell lineage;Tyrosine metabolism;Autoimmune thyroid disease;Jak-STAT signaling pathway;Metabolic pathways
784,0,0,0,0,9,13,0,5,9,0,3,9,"CACNB3;calcium channel, voltage-dependent, beta 3 subunit",GO:0016020//membrane;GO:0005829//cytosol;GO:0016324//apical plasma membrane;GO:0005891//voltage-gated calcium channel complex,GO:0050852//T cell receptor signaling pathway;GO:0007411//axon guidance;GO:0006816//calcium ion transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0070588//calcium ion transmembrane transport;GO:0006810//transport;GO:0051899//membrane depolarization,GO:0019901//protein kinase binding;GO:0005245//voltage-gated calcium channel activity,K04864//Cardiac muscle contraction;Dilated cardiomyopathy;MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM)
7840,106,0,1,48,94,10,70,0,49,0,21,0,ALMS1;Alstrom syndrome 1,GO:0005929//cilium;GO:0005814//centriole;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0000922//spindle pole,GO:0016197//endosomal transport;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0051492//regulation of stress fiber assembly,GO:0005515//protein binding,-
7841,49,0,0,0,0,0,0,0,16,77,0,0,MOGS;mannosyl-oligosaccharide glucosidase,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0006487//protein N-linked glycosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0009311//oligosaccharide metabolic process,GO:0004573//mannosyl-oligosaccharide glucosidase activity,K01228//N-Glycan biosynthesis;Protein processing in endoplasmic reticulum;Metabolic pathways
7844,0,0,0,0,19,25,0,0,27,0,0,0,RNF103;ring finger protein 103,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0007417//central nervous system development,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K12193//Endocytosis
7846,0,0,0,0,133,0,0,0,27,61,4,0,"TUBA1A;tubulin, alpha 1a",GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005881//cytoplasmic microtubule;GO:0005874//microtubule;GO:0005634//nucleus,GO:0051301//cell division;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051084//'de novo' posttranslational protein folding;GO:0007017//microtubule-based process;GO:0044267//cellular protein metabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0051258//protein polymerization;GO:0006457//protein folding;GO:0006184//GTP catabolic process,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0019904//protein domain specific binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07374//Pathogenic Escherichia coli infection;Phagosome;Gap junction
7849,0,2,0,14,59,10,0,44,11,150,17,0,PAX8;paired box 8,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0072108//positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0009653//anatomical structure morphogenesis;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0042981//regulation of apoptotic process;GO:0030878//thyroid gland development;GO:0038194//thyroid-stimulating hormone signaling pathway;GO:2000612//regulation of thyroid-stimulating hormone secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0072221//metanephric distal convoluted tubule development;GO:0001655//urogenital system development;GO:0003337//mesenchymal to epithelial transition involved in metanephros morphogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0071371//cellular response to gonadotropin stimulus;GO:2000611//positive regulation of thyroid hormone generation;GO:0072305//negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis;GO:0072284//metanephric S-shaped body morphogenesis;GO:0042472//inner ear morphogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:1900215//negative regulation of apoptotic process involved in metanephric collecting duct development;GO:0001822//kidney development;GO:1900212//negative regulation of mesenchymal cell apoptotic process involved in metanephros development;GO:1900218//negative regulation of apoptotic process involved in metanephric nephron tubule development;GO:0006351//transcription, DNA-templated;GO:0001823//mesonephros development;GO:0007417//central nervous system development;GO:0072289//metanephric nephron tubule formation;GO:0072207//metanephric epithelium development;GO:0039003//pronephric field specification;GO:0071599//otic vesicle development;GO:2000594//positive regulation of metanephric DCT cell differentiation;GO:0048793//pronephros development;GO:0072278//metanephric comma-shaped body morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding;GO:0004996//thyroid-stimulating hormone receptor activity;GO:0044212//transcription regulatory region DNA binding,K09293//Transcriptional misregulation in cancer;Thyroid cancer;Pathways in cancer
785,1,0,0,25,34,0,9,0,109,0,15,0,"CACNB4;calcium channel, voltage-dependent, beta 4 subunit",GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0005891//voltage-gated calcium channel complex,"GO:0048536//spleen development;GO:0007528//neuromuscular junction development;GO:0006874//cellular calcium ion homeostasis;GO:0048538//thymus development;GO:0048541//Peyer's patch development;GO:0048747//muscle fiber development;GO:0007214//gamma-aminobutyric acid signaling pathway;GO:0007411//axon guidance;GO:0046058//cAMP metabolic process;GO:0007628//adult walking behavior;GO:0035249//synaptic transmission, glutamatergic;GO:0050908//detection of light stimulus involved in visual perception;GO:0014051//gamma-aminobutyric acid secretion;GO:0051899//membrane depolarization;GO:0007268//synaptic transmission;GO:0050852//T cell receptor signaling pathway;GO:1901385//regulation of voltage-gated calcium channel activity;GO:0070588//calcium ion transmembrane transport;GO:0019227//neuronal action potential propagation;GO:0006810//transport",GO:0008331//high voltage-gated calcium channel activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0005245//voltage-gated calcium channel activity,K04865//MAPK signaling pathway;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;Cardiac muscle contraction
7850,0,0,0,0,0,0,0,0,36,0,0,0,"IL1R2;interleukin 1 receptor, type II",GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0019221//cytokine-mediated signaling pathway;GO:0006955//immune response,"GO:0004910//interleukin-1, Type II, blocking receptor activity;GO:0005515//protein binding;GO:0004908//interleukin-1 receptor activity",K04387//Amoebiasis;Transcriptional misregulation in cancer;Hematopoietic cell lineage;HTLV-I infection;Cytokine-cytokine receptor interaction;MAPK signaling pathway
7851,0,0,0,0,1,0,0,0,11,0,0,0,"MALL;mal, T-cell differentiation protein-like",GO:0000139//Golgi membrane;GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0042632//cholesterol homeostasis,GO:0005515//protein binding,K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism
7852,0,0,0,0,0,7,0,0,0,0,0,0,CXCR4;chemokine (C-X-C motif) receptor 4,GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0005769//early endosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005770//late endosome;GO:0005911//cell-cell junction;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle,GO:0001764//neuron migration;GO:0043217//myelin maintenance;GO:0001666//response to hypoxia;GO:0006915//apoptotic process;GO:0070098//chemokine-mediated signaling pathway;GO:0019722//calcium-mediated signaling;GO:0002407//dendritic cell chemotaxis;GO:0016032//viral process;GO:0071345//cellular response to cytokine stimulus;GO:0048714//positive regulation of oligodendrocyte differentiation;GO:0006954//inflammatory response;GO:0030260//entry into host cell;GO:0001569//patterning of blood vessels;GO:0030334//regulation of cell migration;GO:0008354//germ cell migration;GO:0050920//regulation of chemotaxis;GO:0042119//neutrophil activation;GO:0061351//neural precursor cell proliferation;GO:0000187//activation of MAPK activity;GO:0008045//motor neuron axon guidance;GO:0007420//brain development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0009615//response to virus;GO:0007281//germ cell development;GO:0042098//T cell proliferation;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001667//ameboidal cell migration,GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0043130//ubiquitin binding;GO:0001618//virus receptor activity;GO:0015026//coreceptor activity;GO:0032027//myosin light chain binding;GO:0031625//ubiquitin protein ligase binding;GO:0019955//cytokine binding;GO:0016494//C-X-C chemokine receptor activity;GO:0003779//actin binding,K04189//Intestinal immune network for IgA production;Leukocyte transendothelial migration;Chemokine signaling pathway;Axon guidance;Endocytosis;Cytokine-cytokine receptor interaction
7855,0,0,0,0,17,0,0,0,41,0,15,113,FZD5;frizzled class receptor 5,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042995//cell projection;GO:0048471//perinuclear region of cytoplasm;GO:0005923//tight junction,"GO:0007409//axonogenesis;GO:0001525//angiogenesis;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0048469//cell maturation;GO:0032729//positive regulation of interferon-gamma production;GO:0060561//apoptotic process involved in morphogenesis;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification;GO:0008285//negative regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:2000810//regulation of tight junction assembly;GO:0007420//brain development;GO:0060070//canonical Wnt signaling pathway;GO:0060715//syncytiotrophoblast cell differentiation involved in labyrinthine layer development;GO:0060716//labyrinthine layer blood vessel development;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008595//anterior/posterior axis specification, embryo;GO:0000578//embryonic axis specification;GO:0071219//cellular response to molecule of bacterial origin;GO:0033077//T cell differentiation in thymus;GO:0060718//chorionic trophoblast cell differentiation;GO:0031076//embryonic camera-type eye development;GO:0006915//apoptotic process;GO:0043507//positive regulation of JUN kinase activity;GO:0008406//gonad development;GO:0060061//Spemann organizer formation;GO:0031077//post-embryonic camera-type eye development;GO:0030182//neuron differentiation",GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding;GO:0004930//G-protein coupled receptor activity,K02375//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Pathways in cancer
7857,0,0,0,0,0,0,0,0,0,65,0,0,SCG2;secretogranin II,GO:0005615//extracellular space;GO:0030141//secretory granule,GO:0035556//intracellular signal transduction;GO:0006928//cellular component movement;GO:0001938//positive regulation of endothelial cell proliferation;GO:0009306//protein secretion;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0050930//induction of positive chemotaxis;GO:0000165//MAPK cascade;GO:0001525//angiogenesis;GO:0043542//endothelial cell migration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0050918//positive chemotaxis;GO:0048245//eosinophil chemotaxis;GO:0006954//inflammatory response,GO:0005125//cytokine activity;GO:0042056//chemoattractant activity,-
786,0,0,0,0,0,0,0,0,10,0,0,279,"CACNG1;calcium channel, voltage-dependent, gamma subunit 1",GO:0005891//voltage-gated calcium channel complex,GO:0070296//sarcoplasmic reticulum calcium ion transport;GO:0006810//transport;GO:0006936//muscle contraction;GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity,K04866//Cardiac muscle contraction;Dilated cardiomyopathy;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway
7862,0,0,0,0,9,36,21,5,51,1,0,0,"BRPF1;bromodomain and PHD finger containing, 1",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex,"GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
7866,0,1,0,0,14,0,0,1,0,0,6,0,IFRD2;interferon-related developmental regulator 2,GO:0005634//nucleus,-,GO:0005515//protein binding,-
7867,0,1,0,0,11,70,0,0,3,127,5,0,MAPKAPK3;mitogen-activated protein kinase-activated protein kinase 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005829//cytosol,GO:0034134//toll-like receptor 2 signaling pathway;GO:0007265//Ras protein signal transduction;GO:0034138//toll-like receptor 3 signaling pathway;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0044351//macropinocytosis;GO:0032496//response to lipopolysaccharide;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0000187//activation of MAPK activity;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0034162//toll-like receptor 9 signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006950//response to stress;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0034097//response to cytokine,GO:0004674//protein serine/threonine kinase activity;GO:0004708//MAP kinase kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K04444//MAPK signaling pathway;VEGF signaling pathway
7869,0,0,0,0,0,18,0,0,54,0,17,0,"SEMA3B;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B",GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0007267//cell-cell signaling;GO:0007411//axon guidance,GO:0004872//receptor activity,K06840//Axon guidance
7871,0,74,1,35,49,25,21,0,33,0,0,0,SLMAP;sarcolemma associated protein,GO:0042383//sarcolemma;GO:0005790//smooth endoplasmic reticulum;GO:0005887//integral component of plasma membrane;GO:0005815//microtubule organizing center,GO:0006936//muscle contraction,GO:0005515//protein binding,K12478//Tuberculosis;Phagosome;Endocytosis
7873,0,0,1,0,12,0,0,0,4,0,1,0,MANF;mesencephalic astrocyte-derived neurotrophic factor,GO:0005615//extracellular space;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0006986//response to unfolded protein;GO:0002014//vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure,GO:0044822//poly(A) RNA binding;GO:0008083//growth factor activity,-
7874,1,27,2,112,168,13,25,0,35,0,0,0,USP7;ubiquitin specific peptidase 7 (herpes virus-associated),GO:0016605//PML body;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006283//transcription-coupled nucleotide-excision repair;GO:0007275//multicellular organismal development;GO:0010216//maintenance of DNA methylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0016579//protein deubiquitination;GO:0016032//viral process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051090//regulation of sequence-specific DNA binding transcription factor activity,GO:0004197//cysteine-type endopeptidase activity;GO:0031625//ubiquitin protein ligase binding;GO:0002039//p53 binding;GO:0004221//ubiquitin thiolesterase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0008134//transcription factor binding,K11838//Herpes simplex infection;Epstein-Barr virus infection
7879,0,57,1,71,366,0,0,0,21,0,25,0,"RAB7A;RAB7A, member RAS oncogene family",GO:0005770//late endosome;GO:0042470//melanosome;GO:0030670//phagocytic vesicle membrane;GO:0070062//extracellular vesicular exosome;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus;GO:0005765//lysosomal membrane;GO:0097208//alveolar lamellar body;GO:0043231//intracellular membrane-bounded organelle;GO:0005764//lysosome,GO:0006622//protein targeting to lysosome;GO:0045453//bone resorption;GO:0015031//protein transport;GO:0090385//phagosome-lysosome fusion;GO:0008333//endosome to lysosome transport;GO:0006184//GTP catabolic process;GO:0045022//early endosome to late endosome transport;GO:0006897//endocytosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007174//epidermal growth factor catabolic process;GO:0090382//phagosome maturation;GO:0007264//small GTPase mediated signal transduction;GO:0008219//cell death;GO:0090383//phagosome acidification,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0048365//Rac GTPase binding,K07897//Tuberculosis;Amoebiasis;Salmonella infection;Endocytosis;Phagosome
788,0,0,0,2,11,0,0,58,9,0,0,0,"SLC25A20;solute carrier family 25 (carnitine/acylcarnitine translocase), member 20",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0044255//cellular lipid metabolic process;GO:0006853//carnitine shuttle;GO:0044281//small molecule metabolic process,-,-
7881,88,40,0,47,100,9,0,52,70,0,63,0,"KCNAB1;potassium voltage-gated channel, shaker-related subfamily, beta member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007611//learning or memory;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:1901016//regulation of potassium ion transmembrane transporter activity;GO:0006813//potassium ion transport,GO:0005249//voltage-gated potassium channel activity;GO:0015459//potassium channel regulator activity,-
7884,0,0,0,1,6,0,3,87,58,0,0,0,SLBP;stem-loop binding protein,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0005829//cytosol;GO:0030529//ribonucleoprotein complex,GO:0051028//mRNA transport;GO:0006406//mRNA export from nucleus;GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0006398//histone mRNA 3'-end processing;GO:0033260//nuclear cell cycle DNA replication;GO:0006366//transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription,GO:0071207//histone pre-mRNA stem-loop binding;GO:0071208//histone pre-mRNA DCP binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003729//mRNA binding,-
78986,0,0,0,0,0,0,0,0,11,0,0,0,DUSP26;dual specificity phosphatase 26 (putative),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0005739//mitochondrion,GO:1902310//positive regulation of peptidyl-serine dephosphorylation;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045785//positive regulation of cell adhesion,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity;GO:0004647//phosphoserine phosphatase activity;GO:0002039//p53 binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0001102//RNA polymerase II activating transcription factor binding,-
78987,0,0,51,12,53,0,14,0,14,0,15,0,CRELD1;cysteine-rich with EGF-like domains 1,GO:0016021//integral component of membrane,GO:0003279//cardiac septum development;GO:0003197//endocardial cushion development,GO:0005509//calcium ion binding,K08023//TGF-beta signaling pathway
78988,0,2,0,12,13,15,27,9,16,138,0,0,MRPL57;mitochondrial ribosomal protein L57,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
78989,0,0,0,0,0,1,54,0,14,0,10,0,COLEC11;collectin sub-family member 11,GO:0005581//collagen trimer;GO:0005576//extracellular region,GO:0032502//developmental process;GO:0007275//multicellular organismal development,GO:0005537//mannose binding,K10066//Phagosome
78990,93,0,16,0,19,10,0,0,25,0,11,0,"OTUB2;OTU deubiquitinase, ubiquitin aldehyde binding 2",GO:0005634//nucleus,GO:0070536//protein K63-linked deubiquitination;GO:0071108//protein K48-linked deubiquitination;GO:0006520//cellular amino acid metabolic process;GO:0035871//protein K11-linked deubiquitination;GO:0006508//proteolysis;GO:0016579//protein deubiquitination,GO:0004843//ubiquitin-specific protease activity;GO:0008242//omega peptidase activity,-
78992,60,0,16,0,0,30,0,0,0,0,39,0,"YIPF2;Yip1 domain family, member 2",GO:0030133//transport vesicle;GO:0016021//integral component of membrane,-,-,-
78994,0,0,0,0,4,0,0,43,25,0,0,0,PRR14;proline rich 14,-,-,-,K01613//Glycerophospholipid metabolism;Metabolic pathways
78995,63,0,0,0,0,0,0,290,30,0,29,0,C17orf53;chromosome 17 open reading frame 53,-,-,-,-
78996,0,20,0,3,20,0,5,0,15,0,0,0,C7orf49;chromosome 7 open reading frame 49,GO:0005737//cytoplasm,-,-,-
78997,31,0,0,0,0,6,0,0,43,75,0,0,GDAP1L1;ganglioside induced differentiation associated protein 1-like 1,-,-,-,K00799//Drug metabolism - cytochrome P450;Pathways in cancer;Metabolism of xenobiotics by cytochrome P450;Glutathione metabolism;Prostate cancer
78999,0,1,0,0,0,13,0,0,0,0,0,0,LRFN4;leucine rich repeat and fibronectin type III domain containing 4,GO:0016021//integral component of membrane,-,-,K07523//Axon guidance
790,91,0,0,0,1,61,28,1,96,0,20,0,"CAD;carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase",GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0043025//neuronal cell body;GO:0005829//cytosol;GO:0043195//terminal bouton;GO:0016363//nuclear matrix;GO:0042995//cell projection;GO:0005634//nucleus,GO:0046134//pyrimidine nucleoside biosynthetic process;GO:0006206//pyrimidine nucleobase metabolic process;GO:0006228//UTP biosynthetic process;GO:0017144//drug metabolic process;GO:0018107//peptidyl-threonine phosphorylation;GO:0007595//lactation;GO:0051414//response to cortisol;GO:0031000//response to caffeine;GO:0046777//protein autophosphorylation;GO:0006543//glutamine catabolic process;GO:0033574//response to testosterone;GO:0035690//cellular response to drug;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0044205//'de novo' UMP biosynthetic process;GO:0006207//'de novo' pyrimidine nucleobase biosynthetic process;GO:0006541//glutamine metabolic process;GO:0009790//embryo development;GO:0031100//organ regeneration;GO:0014075//response to amine;GO:0007565//female pregnancy;GO:0070409//carbamoyl phosphate biosynthetic process;GO:0044281//small molecule metabolic process,GO:0070335//aspartate binding;GO:0008270//zinc ion binding;GO:0004088//carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity;GO:0019899//enzyme binding;GO:0004070//aspartate carbamoyltransferase activity;GO:0005524//ATP binding;GO:0004151//dihydroorotase activity;GO:0004672//protein kinase activity;GO:0042802//identical protein binding,"K11540//Pyrimidine metabolism;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
79000,2,321,630,622,401,8,71,595,68,2,1016,0,AUNIP;aurora kinase A and ninein interacting protein,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000922//spindle pole,GO:0007051//spindle organization,GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer
79001,0,0,0,0,1,0,15,0,14,0,0,0,"VKORC1;vitamin K epoxide reductase complex, subunit 1",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0042373//vitamin K metabolic process;GO:0043687//post-translational protein modification;GO:0017144//drug metabolic process;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0007596//blood coagulation;GO:0055114//oxidation-reduction process;GO:0060348//bone development;GO:0044267//cellular protein metabolic process,GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0048038//quinone binding,K05357//Ubiquinone and other terpenoid-quinone biosynthesis
79002,175,1,0,0,26,0,0,56,5,0,0,0,C19orf43;chromosome 19 open reading frame 43,-,-,-,-
79003,0,0,0,0,0,0,15,0,20,0,0,0,MIS12;MIS12 kinetochore complex component,GO:0005634//nucleus;GO:0000444//MIS12/MIND type complex;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0051382//kinetochore assembly;GO:0007067//mitotic nuclear division;GO:0007059//chromosome segregation,GO:0005515//protein binding,-
79004,82,17,0,1,8,31,69,0,0,0,0,0,CUEDC2;CUE domain containing 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0005730//nucleolus,-,GO:0005515//protein binding,-
79005,0,0,0,2,2,0,0,0,0,0,0,0,SCNM1;sodium channel modifier 1,GO:0016607//nuclear speck,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0046872//metal ion binding;GO:0019899//enzyme binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01539//Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism
79006,0,0,0,0,0,2,0,62,3,0,0,0,"METRN;meteorin, glial cell differentiation regulator",GO:0005615//extracellular space,GO:0010001//glial cell differentiation;GO:0050772//positive regulation of axonogenesis,-,K00901//Glycerophospholipid metabolism;Phosphatidylinositol signaling system;Glycerolipid metabolism;Metabolic pathways
79007,103,0,0,7,46,0,51,0,38,0,13,0,DBNDD1;dysbindin (dystrobrevin binding protein 1) domain containing 1,GO:0005737//cytoplasm,-,-,-
79009,67,0,2,20,50,19,3,0,0,1,8,0,DDX50;DEAD (Asp-Glu-Ala-Asp) box polypeptide 50,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005886//plasma membrane,GO:0008152//metabolic process,GO:0004386//helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,-
79012,0,0,0,0,3,16,0,0,32,0,0,0,CAMKV;CaM kinase-like vesicle-associated,GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane,GO:0006468//protein phosphorylation,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004672//protein kinase activity,-
79016,0,0,0,0,13,16,12,47,7,0,0,337,DDA1;DET1 and DDB1 associated 1,-,-,-,-
79017,0,1,0,38,28,0,0,0,0,0,4,0,GGCT;gamma-glutamylcyclotransferase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0001836//release of cytochrome c from mitochondria;GO:1901687//glutathione derivative biosynthetic process;GO:0006750//glutathione biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0003839//gamma-glutamylcyclotransferase activity;GO:0042803//protein homodimerization activity,K00682//Glutathione metabolism
79018,0,0,2,20,45,0,25,133,27,0,5,0,GID4;GID complex subunit 4,-,-,-,-
79019,0,0,0,0,0,1,36,0,22,0,0,0,CENPM;centromere protein M,GO:0005634//nucleus;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol,GO:0000278//mitotic cell cycle,-,-
79020,0,18,0,0,41,16,0,0,0,0,0,0,C7orf25;chromosome 7 open reading frame 25,-,-,-,-
79022,0,14,0,6,1,0,0,0,1,0,0,0,TMEM106C;transmembrane protein 106C,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
79023,0,0,0,1,31,0,0,0,12,0,0,0,NUP37;nucleoporin 37kDa,GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0000776//kinetochore;GO:0031080//nuclear pore outer ring;GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore,GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport;GO:0007067//mitotic nuclear division;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0007059//chromosome segregation,GO:0005515//protein binding,K14302//RNA transport
79024,0,0,20,0,2,0,23,0,0,0,0,582,SMIM2;small integral membrane protein 2,GO:0016021//integral component of membrane,-,-,-
79025,0,0,0,0,0,0,0,6,0,0,2,0,C20orf195;chromosome 20 open reading frame 195,GO:0070062//extracellular vesicular exosome,-,-,-
79026,124,226,1,120,432,36,25,18,158,0,0,0,AHNAK;AHNAK nucleoprotein,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0043034//costamere;GO:0030315//T-tubule;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0005925//focal adhesion;GO:0042383//sarcolemma;GO:0044291//cell-cell contact zone;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus,GO:1901385//regulation of voltage-gated calcium channel activity;GO:0051259//protein oligomerization;GO:0043484//regulation of RNA splicing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0097493//structural molecule activity conferring elasticity;GO:0044548//S100 protein binding,K10955//Amoebiasis;Vibrio cholerae infection
79027,0,361,147,146,407,15,56,1048,462,0,472,42,ZNF655;zinc finger protein 655,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
79029,0,0,0,0,0,19,0,0,56,0,20,0,SPATA5L1;spermatogenesis associated 5-like 1,GO:0005737//cytoplasm,-,GO:0005524//ATP binding,K14575//Ribosome biogenesis in eukaryotes;K13525//Protein processing in endoplasmic reticulum;Legionellosis
7903,0,0,0,0,0,29,23,0,23,0,0,0,"ST8SIA4;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4",GO:0030173//integral component of Golgi membrane;GO:0000139//Golgi membrane,GO:0009311//oligosaccharide metabolic process;GO:0006486//protein glycosylation;GO:0006491//N-glycan processing;GO:0006464//cellular protein modification process;GO:0097503//sialylation;GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0001574//ganglioside biosynthetic process,"GO:0033691//sialic acid binding;GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity",-
79031,0,0,0,0,20,0,0,0,10,0,0,0,PDCL3;phosducin-like 3,GO:0005737//cytoplasm,GO:0001938//positive regulation of endothelial cell proliferation;GO:2000059//negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0006457//protein folding;GO:0001525//angiogenesis;GO:0050730//regulation of peptidyl-tyrosine phosphorylation;GO:0016032//viral process;GO:0045766//positive regulation of angiogenesis,GO:0044183//protein binding involved in protein folding;GO:0043184//vascular endothelial growth factor receptor 2 binding;GO:0005515//protein binding,K08327//Olfactory transduction
79034,0,0,0,0,8,0,0,1,13,0,0,0,C7orf26;chromosome 7 open reading frame 26,-,-,-,-
79035,0,0,0,0,15,0,0,0,29,6,0,0,NABP2;nucleic acid binding protein 2,GO:0005634//nucleus;GO:0070876//SOSS complex;GO:0005730//nucleolus,GO:0006974//cellular response to DNA damage stimulus;GO:0007093//mitotic cell cycle checkpoint;GO:0000724//double-strand break repair via homologous recombination;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation,GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
79036,0,5,1,5,42,0,0,0,28,0,8,0,KXD1;KxDL motif containing 1,GO:0031083//BLOC-1 complex,GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,-
79037,0,0,1,6,8,10,16,0,0,0,0,513,PVRIG;poliovirus receptor related immunoglobulin domain containing,GO:0016021//integral component of membrane,-,-,-
79038,0,40,1,28,51,0,0,0,8,0,0,0,"ZFYVE21;zinc finger, FYVE domain containing 21",GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005925//focal adhesion;GO:0005768//endosome,-,GO:0046872//metal ion binding,K00921//Regulation of actin cytoskeleton;Phagosome;Phosphatidylinositol signaling system;Inositol phosphate metabolism
79039,0,29,0,0,5,45,12,53,34,0,15,0,DDX54;DEAD (Asp-Glu-Ala-Asp) box polypeptide 54,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006396//RNA processing;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0006200//ATP catabolic process",GO:0005102//receptor binding;GO:0003714//transcription corepressor activity;GO:0005524//ATP binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0030331//estrogen receptor binding,-
79041,0,0,0,6,0,0,53,0,19,0,0,340,TMEM38A;transmembrane protein 38A,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0031965//nuclear membrane;GO:0033017//sarcoplasmic reticulum membrane,GO:0071805//potassium ion transmembrane transport,GO:0005267//potassium channel activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K14209//Protein digestion and absorption;K11447//Transcriptional misregulation in cancer
79042,0,0,1,2,9,0,25,0,0,1,0,0,TSEN34;TSEN34 tRNA splicing endonuclease subunit,GO:0000214//tRNA-intron endonuclease complex;GO:0005730//nucleolus,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0000379//tRNA-type intron splice site recognition and cleavage;GO:0006397//mRNA processing",GO:0016829//lyase activity;GO:0003676//nucleic acid binding;GO:0000213//tRNA-intron endonuclease activity,-
79047,87,0,0,0,12,1,14,0,53,0,0,0,KCTD15;potassium channel tetramerization domain containing 15,-,GO:0051260//protein homooligomerization;GO:0007275//multicellular organismal development,-,-
79048,0,0,0,68,72,8,21,0,81,89,6,1,SECISBP2;SECIS binding protein 2,GO:0005730//nucleolus;GO:0030529//ribonucleoprotein complex;GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0043021//ribonucleoprotein complex binding;GO:0003730//mRNA 3'-UTR binding;GO:0035368//selenocysteine insertion sequence binding,-
7905,0,0,0,51,89,24,0,0,0,0,0,0,REEP5;receptor accessory protein 5,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
79050,1,0,0,0,0,0,16,0,35,0,0,0,NOC4L;nucleolar complex associated 4 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0031965//nuclear membrane,GO:0006364//rRNA processing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
79053,0,0,0,0,0,21,0,0,20,0,0,0,"ALG8;ALG8, alpha-1,3-glucosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0097502//mannosylation,"GO:0000033//alpha-1,3-mannosyltransferase activity",K03849//Metabolic pathways;N-Glycan biosynthesis
79054,0,120,1,69,143,22,14,75,67,138,9,0,"TRPM8;transient receptor potential cation channel, subfamily M, member 8",GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005789//endoplasmic reticulum membrane,GO:0034220//ion transmembrane transport;GO:0009409//response to cold;GO:0070207//protein homotrimerization;GO:0055085//transmembrane transport;GO:0016048//detection of temperature stimulus;GO:0070588//calcium ion transmembrane transport;GO:0006874//cellular calcium ion homeostasis;GO:0051289//protein homotetramerization;GO:0050955//thermoception,GO:0005262//calcium channel activity;GO:0042803//protein homodimerization activity,-
79056,0,0,0,8,9,0,0,37,40,2,0,327,PRRG4;proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane),GO:0005576//extracellular region;GO:0016021//integral component of membrane,-,GO:0005509//calcium ion binding,K11447//Transcriptional misregulation in cancer
79057,0,0,0,0,0,0,38,0,0,0,0,0,PRRG3;proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane),GO:0005576//extracellular region;GO:0016021//integral component of membrane,-,GO:0005509//calcium ion binding,K01320//Complement and coagulation cascades
79058,3,0,0,0,2,23,36,1,29,0,0,0,"ASPSCR1;alveolar soft part sarcoma chromosome region, candidate 1",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0019898//extrinsic component of membrane;GO:0012505//endomembrane system;GO:0005829//cytosol;GO:0009898//cytoplasmic side of plasma membrane;GO:0012506//vesicle membrane,GO:0042593//glucose homeostasis;GO:0046324//regulation of glucose import;GO:0061024//membrane organization;GO:0006886//intracellular protein transport,GO:0005515//protein binding,K15627//Transcriptional misregulation in cancer
79064,0,41,0,16,21,0,13,49,12,0,23,41,TMEM223;transmembrane protein 223,GO:0016021//integral component of membrane,-,-,-
79065,87,0,0,0,0,14,0,0,33,0,4,0,ATG9A;autophagy related 9A,GO:0005789//endoplasmic reticulum membrane;GO:0055037//recycling endosome;GO:0031902//late endosome membrane;GO:0005776//autophagic vacuole;GO:0000421//autophagic vacuole membrane;GO:0031410//cytoplasmic vesicle;GO:0005802//trans-Golgi network;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0000407//pre-autophagosomal structure;GO:0005768//endosome,GO:0000422//mitochondrion degradation;GO:0015031//protein transport;GO:0044805//late nucleophagy;GO:0000045//autophagic vacuole assembly;GO:0034497//protein localization to pre-autophagosomal structure;GO:0034727//piecemeal microautophagy of nucleus,GO:0005515//protein binding,-
79066,0,0,0,9,35,10,7,0,26,0,0,0,METTL16;methyltransferase like 16,-,GO:0032259//methylation,GO:0044822//poly(A) RNA binding;GO:0008168//methyltransferase activity,-
79068,0,0,0,2,108,9,56,0,22,0,0,0,FTO;fat mass and obesity associated,GO:0016607//nuclear speck;GO:0005634//nucleus,GO:0035552//oxidative single-stranded DNA demethylation;GO:0042245//RNA repair;GO:0080111//DNA demethylation;GO:0040014//regulation of multicellular organism growth;GO:0010883//regulation of lipid storage;GO:0044065//regulation of respiratory system process;GO:0070989//oxidative demethylation;GO:0006307//DNA dealkylation involved in DNA repair;GO:0070350//regulation of white fat cell proliferation;GO:0060612//adipose tissue development;GO:0001659//temperature homeostasis;GO:0035553//oxidative single-stranded RNA demethylation,GO:0035515//oxidative RNA demethylase activity;GO:0043734//DNA-N1-methyladenine dioxygenase activity;GO:0008198//ferrous iron binding;GO:0035516//oxidative DNA demethylase activity,K01539//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
79070,0,0,0,0,0,0,19,0,30,0,0,0,KDELC1;KDEL (Lys-Asp-Glu-Leu) containing 1,GO:0005788//endoplasmic reticulum lumen,-,-,K13667//Other types of O-glycan biosynthesis
79071,102,1,0,0,1,0,0,0,18,0,0,0,ELOVL6;ELOVL fatty acid elongase 6,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,"GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0044255//cellular lipid metabolic process;GO:0042759//long-chain fatty acid biosynthetic process;GO:0019432//triglyceride biosynthetic process","GO:0016747//transferase activity, transferring acyl groups other than amino-acyl groups;GO:0005515//protein binding",K10203//Fatty acid elongation;Biosynthesis of unsaturated fatty acids
79072,0,0,0,3,11,0,0,45,13,0,0,0,FASTKD3;FAST kinase domains 3,GO:0005739//mitochondrion,GO:0045333//cellular respiration;GO:0006468//protein phosphorylation,GO:0004672//protein kinase activity;GO:0044822//poly(A) RNA binding,-
79073,0,0,0,0,0,0,0,0,29,0,25,0,TMEM109;transmembrane protein 109,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0033017//sarcoplasmic reticulum membrane;GO:0005640//nuclear outer membrane,GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0060548//negative regulation of cell death;GO:0071480//cellular response to gamma radiation,-,-
79074,3,32,20,3,21,0,0,0,0,0,0,0,C2orf49;chromosome 2 open reading frame 49,GO:0072669//tRNA-splicing ligase complex,GO:0048598//embryonic morphogenesis,-,-
79077,0,0,0,13,31,0,0,0,1,0,0,0,DCTPP1;dCTP pyrophosphatase 1,GO:0005829//cytosol,GO:0009143//nucleoside triphosphate catabolic process;GO:0051289//protein homotetramerization,GO:0032556//pyrimidine deoxyribonucleotide binding;GO:0047429//nucleoside-triphosphate diphosphatase activity;GO:0000287//magnesium ion binding;GO:0047840//dCTP diphosphatase activity,-
79078,0,0,0,2,13,0,0,0,13,0,0,0,C1orf50;chromosome 1 open reading frame 50,-,-,-,-
79080,0,0,0,27,0,49,0,16,36,0,55,0,CCDC86;coiled-coil domain containing 86,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0016032//viral process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
79081,0,0,0,2,18,0,0,0,13,0,0,0,C11orf48;chromosome 11 open reading frame 48,-,-,-,-
79083,0,595,9,193,603,41,34,78,115,116,89,0,MLPH;melanophilin,GO:0070062//extracellular vesicular exosome;GO:0035371//microtubule plus-end;GO:0005815//microtubule organizing center;GO:0030864//cortical actin cytoskeleton;GO:0001725//stress fiber,GO:0006605//protein targeting;GO:0030318//melanocyte differentiation;GO:0032400//melanosome localization,GO:0046872//metal ion binding;GO:0051010//microtubule plus-end binding;GO:0017137//Rab GTPase binding;GO:0003779//actin binding;GO:0031489//myosin V binding,-
79084,0,0,0,12,21,0,0,0,4,0,1,62,WDR77;WD repeat domain 77,GO:0005737//cytoplasm;GO:0034709//methylosome;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,GO:0008284//positive regulation of cell proliferation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0060770//negative regulation of epithelial cell proliferation involved in prostate gland development;GO:0016070//RNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0034660//ncRNA metabolic process;GO:0060528//secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development;GO:0010467//gene expression,GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0005515//protein binding,-
79085,91,0,0,4,1,0,26,1,5,137,8,0,"SLC25A23;solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport;GO:0071277//cellular response to calcium ion;GO:0002082//regulation of oxidative phosphorylation;GO:0043457//regulation of cellular respiration,GO:0005509//calcium ion binding,-
79086,0,35,1,23,68,0,0,0,0,0,0,0,SMIM7;small integral membrane protein 7,GO:0016021//integral component of membrane,-,-,-
79087,0,0,0,0,0,0,0,26,9,0,0,0,"ALG12;ALG12, alpha-1,6-mannosyltransferase",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0097502//mannosylation;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006487//protein N-linked glycosylation;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,"GO:0052917//dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity",K03847//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
79088,0,0,0,0,24,0,0,0,0,0,0,0,ZNF426;zinc finger protein 426,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79089,0,1,0,2,19,16,24,0,14,0,28,0,TMUB2;transmembrane and ubiquitin-like domain containing 2,GO:0016021//integral component of membrane,-,-,-
79090,0,0,0,0,5,0,0,0,5,0,0,0,TRAPPC6A;trafficking protein particle complex 6A,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0016192//vesicle-mediated transport,GO:0005515//protein binding,-
79091,0,0,0,0,0,0,39,0,8,0,0,0,METTL22;methyltransferase like 22,GO:0005634//nucleus,GO:0032259//methylation,GO:0008168//methyltransferase activity,-
79092,46,0,43,0,35,13,1,173,42,0,31,0,"CARD14;caspase recruitment domain family, member 14",GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0001934//positive regulation of protein phosphorylation;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043066//negative regulation of apoptotic process,GO:0050700//CARD domain binding,K07367//B cell receptor signaling pathway;T cell receptor signaling pathway;NF-kappa B signaling pathway
79095,0,1,0,0,0,0,0,0,0,0,0,0,C9orf16;chromosome 9 open reading frame 16,-,-,-,-
790955,0,1,0,8,21,18,0,0,0,0,16,0,C11orf83;chromosome 11 open reading frame 83,GO:0005576//extracellular region,-,-,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
79096,0,76,36,25,48,30,0,66,24,0,104,0,C11orf49;chromosome 11 open reading frame 49,GO:0005634//nucleus;GO:0005730//nucleolus,-,-,-
79097,0,0,0,0,0,0,0,0,30,0,0,0,TRIM48;tripartite motif containing 48,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
79098,0,97,0,175,338,17,0,1,69,0,1,0,C1orf116;chromosome 1 open reading frame 116,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,-,-
79101,0,0,0,0,2,0,0,0,44,0,0,0,"TAF1D;TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa",GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005634//nucleus,"GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding,-
79102,0,0,0,0,1,0,16,0,9,0,0,0,RNF26;ring finger protein 26,GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
79109,0,36,1,34,66,0,0,58,21,0,0,0,MAPKAP1;mitogen-activated protein kinase associated protein 1,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005829//cytosol;GO:0005634//nucleus,GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0031295//T cell costimulation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0021762//substantia nigra development;GO:0046580//negative regulation of Ras protein signal transduction,"GO:0019901//protein kinase binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0070300//phosphatidic acid binding;GO:0017016//Ras GTPase binding",-
7913,0,17,0,38,144,0,0,0,1,0,0,0,DEK;DEK proto-oncogene,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:2000779//regulation of double-strand break repair;GO:0019079//viral genome replication;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0007165//signal transduction,GO:0042393//histone binding;GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
79132,0,0,24,0,0,0,0,0,35,0,1,0,DHX58;DEXH (Asp-Glu-X-His) box polypeptide 58,GO:0005737//cytoplasm,GO:0039536//negative regulation of RIG-I signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:1900245//positive regulation of MDA-5 signaling pathway;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0039534//negative regulation of MDA-5 signaling pathway;GO:0032481//positive regulation of type I interferon production;GO:1900246//positive regulation of RIG-I signaling pathway;GO:0045088//regulation of innate immune response;GO:0045824//negative regulation of innate immune response;GO:0009615//response to virus;GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003725//double-stranded RNA binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0003727//single-stranded RNA binding;GO:0005515//protein binding,K12649//RIG-I-like receptor signaling pathway
79133,0,0,0,12,0,0,0,0,12,0,7,0,"NDUFAF5;NADH dehydrogenase (ubiquinone) complex I, assembly factor 5",GO:0031314//extrinsic component of mitochondrial inner membrane,GO:0032259//methylation;GO:0032981//mitochondrial respiratory chain complex I assembly,GO:0008168//methyltransferase activity,K10718//Insect hormone biosynthesis
79134,0,0,0,0,1,23,4,0,43,0,0,0,TMEM185B;transmembrane protein 185B,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00547//Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79135,0,0,0,3,0,0,19,0,0,0,0,0,APOO;apolipoprotein O,GO:0034364//high-density lipoprotein particle;GO:0034362//low-density lipoprotein particle;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0034361//very-low-density lipoprotein particle;GO:0005615//extracellular space,GO:0006869//lipid transport,-,-
79137,0,0,0,5,13,0,14,0,18,0,0,115,"FAM134A;family with sequence similarity 134, member A",GO:0016021//integral component of membrane,-,-,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
79139,0,0,0,0,6,0,0,52,7,0,11,0,DERL1;derlin 1,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0000836//Hrd1p ubiquitin ligase complex;GO:0005769//early endosome;GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,"GO:0030970//retrograde protein transport, ER to cytosol;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0006986//response to unfolded protein;GO:0045184//establishment of protein localization;GO:0019060//intracellular transport of viral protein in host cell",GO:0004872//receptor activity;GO:0042288//MHC class I protein binding;GO:0005515//protein binding,K11519//Amyotrophic lateral sclerosis (ALS);Protein processing in endoplasmic reticulum
79142,0,0,1,0,21,0,0,0,0,8,0,627,PHF23;PHD finger protein 23,-,-,GO:0008270//zinc ion binding,-
79143,0,0,0,0,0,0,2,1,0,0,17,0,MBOAT7;membrane bound O-acyltransferase domain containing 7,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0021591//ventricular system development;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0021819//layer formation in cerebral cortex,GO:0071617//lysophospholipid acyltransferase activity;GO:0005515//protein binding,K13516//Glycerophospholipid metabolism
79144,0,12,1,1,22,0,0,1,16,0,0,0,PPDPF;pancreatic progenitor cell differentiation and proliferation factor,-,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development,-,-
79145,0,0,1,37,116,0,0,0,0,0,0,0,CHCHD7;coiled-coil-helix-coiled-coil-helix domain containing 7,GO:0005758//mitochondrial intermembrane space,-,-,-
79147,124,0,0,0,0,17,0,0,18,0,13,0,FKRP;fukutin related protein,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005615//extracellular space;GO:0042383//sarcolemma;GO:0005794//Golgi apparatus;GO:0016010//dystrophin-associated glycoprotein complex;GO:0005791//rough endoplasmic reticulum,GO:0009101//glycoprotein biosynthetic process;GO:0016485//protein processing,GO:0016740//transferase activity,-
79148,0,0,0,0,0,24,54,0,19,0,14,0,MMP28;matrix metallopeptidase 28,GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,GO:0010760//negative regulation of macrophage chemotaxis;GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004222//metalloendopeptidase activity,-
79149,0,0,0,0,0,0,0,0,54,0,0,0,ZSCAN5A;zinc finger and SCAN domain containing 5A,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
7915,0,1,1,1,34,0,7,2,55,294,51,0,"ALDH5A1;aldehyde dehydrogenase 5 family, member A1",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006536//glutamate metabolic process;GO:0042135//neurotransmitter catabolic process;GO:0007417//central nervous system development;GO:0007269//neurotransmitter secretion;GO:0006541//glutamine metabolic process;GO:0006681//galactosylceramide metabolic process;GO:0009450//gamma-aminobutyric acid catabolic process;GO:0051289//protein homotetramerization;GO:0046459//short-chain fatty acid metabolic process;GO:0007268//synaptic transmission;GO:0006650//glycerophospholipid metabolic process;GO:0006749//glutathione metabolic process;GO:0006678//glucosylceramide metabolic process;GO:0006006//glucose metabolic process;GO:0009791//post-embryonic development;GO:0022904//respiratory electron transport chain;GO:0006083//acetate metabolic process;GO:0006105//succinate metabolic process,GO:0004777//succinate-semialdehyde dehydrogenase (NAD+) activity;GO:0042803//protein homodimerization activity;GO:0009013//succinate-semialdehyde dehydrogenase [NAD(P)+] activity,"K00139//Metabolic pathways;Alanine, aspartate and glutamate metabolism;Butanoate metabolism"
79152,0,0,0,0,0,0,11,0,35,0,0,0,FA2H;fatty acid 2-hydroxylase,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0032287//peripheral nervous system myelin maintenance;GO:0042634//regulation of hair cycle;GO:0006633//fatty acid biosynthetic process;GO:0008219//cell death;GO:0032286//central nervous system myelin maintenance;GO:0042127//regulation of cell proliferation;GO:0030258//lipid modification;GO:0006665//sphingolipid metabolic process;GO:0001949//sebaceous gland cell differentiation;GO:0055114//oxidation-reduction process,GO:0020037//heme binding;GO:0080132//fatty acid alpha-hydroxylase activity;GO:0005506//iron ion binding,-
79153,0,0,0,0,0,0,0,0,36,0,15,0,GDPD3;glycerophosphodiester phosphodiesterase domain containing 3,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process,GO:0008889//glycerophosphodiester phosphodiesterase activity;GO:0046872//metal ion binding,K01126//Sphingolipid metabolism;Glycerophospholipid metabolism;Other glycan degradation
79154,0,0,0,0,28,0,0,0,0,0,0,0,DHRS11;dehydrogenase/reductase (SDR family) member 11,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K11147//Retinol metabolism;Peroxisome;Metabolic pathways;K16066//Metabolic pathways;Pyrimidine metabolism
79155,0,0,0,0,3,15,0,0,22,5,16,0,TNIP2;TNFAIP3 interacting protein 2,GO:0005634//nucleus;GO:0005829//cytosol,"GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0050821//protein stabilization;GO:0006351//transcription, DNA-templated;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043032//positive regulation of macrophage activation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050871//positive regulation of B cell activation;GO:0034134//toll-like receptor 2 signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0034162//toll-like receptor 9 signaling pathway;GO:0006915//apoptotic process;GO:0071222//cellular response to lipopolysaccharide;GO:0023035//CD40 signaling pathway;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070498//interleukin-1-mediated signaling pathway",GO:0031593//polyubiquitin binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
79156,58,0,0,0,0,0,0,101,0,0,0,0,"PLEKHF1;pleckstrin homology domain containing, family F (with FYVE domain) member 1",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005765//lysosomal membrane;GO:0005764//lysosome;GO:0005768//endosome;GO:0010008//endosome membrane,GO:0006915//apoptotic process;GO:0072659//protein localization to plasma membrane;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0007032//endosome organization;GO:0016050//vesicle organization;GO:0010508//positive regulation of autophagy,GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0046872//metal ion binding;GO:0070273//phosphatidylinositol-4-phosphate binding,-
79157,1,768,166,379,819,0,2,406,189,0,916,2,MFSD11;major facilitator superfamily domain containing 11,GO:0016021//integral component of membrane,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K12891//Herpes simplex infection;Spliceosome;K11447//Transcriptional misregulation in cancer
79158,132,0,0,32,29,0,0,0,65,0,3,0,"GNPTAB;N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits",GO:0005634//nucleus;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0009306//protein secretion;GO:0046835//carbohydrate phosphorylation;GO:0007040//lysosome organization;GO:0030154//cell differentiation,GO:0005509//calcium ion binding;GO:0008134//transcription factor binding;GO:0003976//UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity,K08239//Lysosome
79159,0,0,0,1,0,14,0,77,9,0,15,0,NOL12;nucleolar protein 12,GO:0005730//nucleolus,-,GO:0019843//rRNA binding;GO:0044822//poly(A) RNA binding,-
7916,0,0,0,0,0,0,1,0,0,0,0,0,PRRC2A;proline-rich coiled-coil 2A,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
79161,0,1,0,0,0,0,0,0,0,0,0,0,"TMEM243;transmembrane protein 243, mitochondrial",GO:0016021//integral component of membrane,-,-,-
79165,0,14,1,4,0,0,0,0,0,0,8,0,LENG1;leukocyte receptor cluster (LRC) member 1,-,-,-,-
79166,0,0,0,0,0,0,0,0,4,0,0,0,LILRP2;leukocyte immunoglobulin-like receptor pseudogene 2,-,-,-,K06512//B cell receptor signaling pathway;Osteoclast differentiation
79168,0,0,0,0,0,39,18,0,0,0,0,0,"LILRA6;leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6",GO:0016021//integral component of membrane,GO:0002376//immune system process,-,K06512//Osteoclast differentiation;B cell receptor signaling pathway
79169,0,0,0,0,1,14,0,4,0,0,5,0,C1orf35;chromosome 1 open reading frame 35,-,-,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
79170,0,20,0,13,26,0,0,43,23,1,0,0,PRR15L;proline rich 15-like,-,-,-,-
79171,0,0,0,4,1,0,0,0,22,49,29,0,RBM42;RNA binding motif protein 42,GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
79172,94,627,63,410,651,54,0,1,61,0,464,0,CENPO;centromere protein O,GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006334//nucleosome assembly;GO:0000278//mitotic cell cycle;GO:0034080//CENP-A containing nucleosome assembly,-,-
79173,0,0,0,0,0,0,0,0,0,0,0,1,C19orf57;chromosome 19 open reading frame 57,-,GO:0007275//multicellular organismal development,GO:0005515//protein binding,K06236//Focal adhesion;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction
79174,0,0,0,0,0,0,1,0,27,0,0,0,CRELD2;cysteine-rich with EGF-like domains 2,GO:0005794//Golgi apparatus;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum,-,GO:0005515//protein binding;GO:0005509//calcium ion binding,K06824//ECM-receptor interaction;K08023//TGF-beta signaling pathway
79175,0,0,0,0,17,20,0,0,11,7,0,0,ZNF343;zinc finger protein 343,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
79176,0,0,32,7,10,0,0,0,21,35,12,0,FBXL15;F-box and leucine-rich repeat protein 15,GO:0019005//SCF ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0030282//bone mineralization;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0030513//positive regulation of BMP signaling pathway;GO:0009953//dorsal/ventral pattern formation,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,-
79177,0,0,0,0,0,0,0,1,8,0,0,264,ZNF576;zinc finger protein 576,GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79178,0,0,20,7,0,0,0,0,0,0,0,0,THTPA;thiamine triphosphatase,GO:0005829//cytosol,GO:0006772//thiamine metabolic process;GO:0006766//vitamin metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0016311//dephosphorylation;GO:0042723//thiamine-containing compound metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0042357//thiamine diphosphate metabolic process,GO:0050333//thiamin-triphosphatase activity;GO:0000287//magnesium ion binding;GO:0016787//hydrolase activity,K05307//Metabolic pathways;Thiamine metabolism
7918,0,0,1,0,0,0,0,0,0,1,0,0,GPANK1;G patch domain and ankyrin repeats 1,-,-,GO:0003676//nucleic acid binding,K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
79180,0,2,0,4,16,8,0,96,27,0,1,0,"EFHD2;EF-hand domain family, member D2",GO:0045121//membrane raft,-,GO:0005509//calcium ion binding,-
79183,0,0,0,23,32,0,0,0,19,0,0,0,TTPAL;tocopherol (alpha) transfer protein-like,GO:0005622//intracellular;GO:0016020//membrane,GO:0006810//transport,GO:0005215//transporter activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
79184,0,2,1,16,21,0,0,0,19,0,0,0,"BRCC3;BRCA1/BRCA2-containing complex, subunit 3",GO:0000151//ubiquitin ligase complex;GO:0000152//nuclear ubiquitin ligase complex;GO:0005634//nucleus;GO:0070531//BRCA1-A complex;GO:0070552//BRISC complex;GO:0005730//nucleolus,GO:0010212//response to ionizing radiation;GO:0031572//G2 DNA damage checkpoint;GO:0070537//histone H2A K63-linked deubiquitination;GO:0006302//double-strand break repair;GO:0050790//regulation of catalytic activity;GO:0070536//protein K63-linked deubiquitination;GO:0045739//positive regulation of DNA repair;GO:0010165//response to X-ray;GO:0006508//proteolysis,GO:0030234//enzyme regulator activity;GO:0004221//ubiquitin thiolesterase activity;GO:0008237//metallopeptidase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004843//ubiquitin-specific protease activity;GO:0031593//polyubiquitin binding,-
79187,0,0,1,0,0,0,0,0,9,109,0,0,FSD1;fibronectin type III and SPRY domain containing 1,GO:0005874//microtubule;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0032154//cleavage furrow,GO:0007067//mitotic nuclear division,-,K08285//Ubiquitin mediated proteolysis
79188,0,24,0,0,0,0,45,77,18,190,0,0,TMEM43;transmembrane protein 43,GO:0005637//nuclear inner membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0071763//nuclear membrane organization,GO:0005515//protein binding,-
7919,0,0,0,0,0,0,0,3,0,0,0,0,DDX39B;DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B,GO:0005737//cytoplasm;GO:0005688//U6 snRNP;GO:0005634//nucleus;GO:0005687//U4 snRNP;GO:0005681//spliceosomal complex;GO:0000346//transcription export complex;GO:0016607//nuclear speck,"GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0006200//ATP catabolic process;GO:2000002//negative regulation of DNA damage checkpoint;GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0008380//RNA splicing;GO:0010501//RNA secondary structure unwinding;GO:0000398//mRNA splicing, via spliceosome;GO:0000245//spliceosomal complex assembly",GO:0044822//poly(A) RNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0005515//protein binding;GO:0043008//ATP-dependent protein binding;GO:0017070//U6 snRNA binding;GO:0005524//ATP binding;GO:0030621//U4 snRNA binding;GO:0008186//RNA-dependent ATPase activity,K12812//mRNA surveillance pathway;RNA transport;Influenza A;Spliceosome
79190,0,0,0,0,0,0,22,1,33,154,0,97,IRX6;iroquois homeobox 6,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K09355//Transcriptional misregulation in cancer;K15613//Transcriptional misregulation in cancer
79191,0,0,0,0,16,7,11,105,0,0,0,34,IRX3;iroquois homeobox 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030424//axon,"GO:0006351//transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0001656//metanephros development;GO:0045666//positive regulation of neuron differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0007498//mesoderm development",GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer
79192,0,0,0,0,0,0,4,0,0,0,0,0,IRX1;iroquois homeobox 1,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding,K15613//Transcriptional misregulation in cancer
79228,0,0,0,8,53,0,0,119,32,1,20,620,THOC6;THO complex 6 homolog (Drosophila),GO:0005634//nucleus;GO:0000445//THO complex part of transcription export complex;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0000346//transcription export complex,GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0008380//RNA splicing;GO:0007417//central nervous system development;GO:0006397//mRNA processing,GO:0003723//RNA binding,K13175//RNA transport
7923,0,0,0,0,0,0,0,0,1,0,0,0,HSD17B8;hydroxysteroid (17-beta) dehydrogenase 8,GO:0005740//mitochondrial envelope;GO:0005759//mitochondrial matrix;GO:0005886//plasma membrane,GO:0055114//oxidation-reduction process;GO:0006633//fatty acid biosynthetic process;GO:0006703//estrogen biosynthetic process;GO:0008209//androgen metabolic process,GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0003857//3-hydroxyacyl-CoA dehydrogenase activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0005515//protein binding,K13370//Steroid hormone biosynthesis;Metabolic pathways
79230,0,0,3,9,1,18,0,0,18,0,2,0,ZNF557;zinc finger protein 557,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79258,38,245,161,161,203,24,0,203,132,0,452,324,MMEL1;membrane metallo-endopeptidase-like 1,GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
79269,0,0,10,47,60,1,0,0,35,0,18,0,DCAF10;DDB1 and CUL4 associated factor 10,GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:0016567//protein ubiquitination,-,-
79290,0,0,0,0,0,8,0,0,39,0,0,0,"OR13A1;olfactory receptor, family 13, subfamily A, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
793,0,0,0,0,0,23,24,0,0,0,0,0,"CALB1;calbindin 1, 28kDa",GO:0045202//synapse;GO:0030424//axon;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005634//nucleus;GO:0043025//neuronal cell body,GO:0071310//cellular response to organic substance;GO:0051480//cytosolic calcium ion homeostasis;GO:0007614//short-term memory;GO:0035502//metanephric part of ureteric bud development;GO:0072286//metanephric connecting tubule development;GO:0048167//regulation of synaptic plasticity;GO:0010842//retina layer formation;GO:0072221//metanephric distal convoluted tubule development;GO:0007626//locomotory behavior;GO:0072205//metanephric collecting duct development;GO:0007616//long-term memory,GO:0005499//vitamin D binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K14757//Endocrine and other factor-regulated calcium reabsorption
79310,0,0,0,0,0,0,0,0,15,0,0,0,"OR5H2;olfactory receptor, family 5, subfamily H, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
79315,0,0,0,0,0,0,0,0,30,0,0,0,"OR7E91P;olfactory receptor, family 7, subfamily E, member 91 pseudogene",-,-,-,K04257//Olfactory transduction
79317,25,0,0,0,0,27,0,0,0,0,0,0,"OR4K5;olfactory receptor, family 4, subfamily K, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
79324,0,0,0,0,0,0,0,0,56,0,0,0,"OR51G1;olfactory receptor, family 51, subfamily G, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
79334,0,0,0,0,0,0,0,0,14,0,0,0,"OR11H2;olfactory receptor, family 11, subfamily H, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
79339,0,0,0,0,0,0,0,0,14,0,0,0,"OR51B4;olfactory receptor, family 51, subfamily B, member 4",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
79345,0,0,0,0,0,0,0,0,12,0,0,0,"OR51B2;olfactory receptor, family 51, subfamily B, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
7936,2,0,0,0,0,0,0,0,0,0,0,0,NELFE;negative elongation factor complex member E,GO:0032021//NELF complex;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0010467//gene expression;GO:0050434//positive regulation of viral transcription;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0006366//transcription from RNA polymerase II promoter,GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
79363,0,0,0,0,0,25,2,0,0,0,0,0,RSG1;REM2 and RAB-like small GTPase 1,GO:0036064//ciliary basal body;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0042384//cilium assembly;GO:0007264//small GTPase mediated signal transduction;GO:0031338//regulation of vesicle fusion;GO:0017157//regulation of exocytosis;GO:0006887//exocytosis;GO:0034613//cellular protein localization,GO:0005525//GTP binding,-
79364,0,0,0,1,14,14,0,1,37,0,0,0,ZXDC;ZXD family zinc finger C,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0030275//LRR domain binding;GO:0070742//C2H2 zinc finger domain binding;GO:0003676//nucleic acid binding,-
79365,0,0,1,8,0,0,0,0,37,0,0,0,"BHLHE41;basic helix-loop-helix family, member e41",GO:0005634//nucleus,"GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0009887//organ morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010944//negative regulation of transcription by competitive promoter binding;GO:0030154//cell differentiation;GO:0010832//negative regulation of myotube differentiation",GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0070888//E-box binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0043425//bHLH transcription factor binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0043426//MRF binding;GO:0042826//histone deacetylase binding,K03730//Circadian rhythm - mammal
79366,0,0,0,0,24,0,0,0,18,0,0,0,HMGN5;high mobility group nucleosome binding domain 5,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000785//chromatin,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0031492//nucleosomal DNA binding;GO:0044822//poly(A) RNA binding,K11299//Herpes simplex infection
79369,0,0,0,0,0,19,0,41,9,0,12,0,"B3GNT4;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0044267//cellular protein metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0008378//galactosyltransferase activity,K07971//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
79370,0,0,19,0,0,1,0,0,0,0,0,0,BCL2L14;BCL2-like 14 (apoptosis facilitator),GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005829//cytosol;GO:0043229//intracellular organelle;GO:0005737//cytoplasm,GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0019901//protein kinase binding,K03211//Transcriptional misregulation in cancer;Dorso-ventral axis formation;MAPK signaling pathway - fly
794,64,0,0,0,0,21,45,0,13,207,9,0,CALB2;calbindin 2,GO:0005737//cytoplasm;GO:0005921//gap junction;GO:0005634//nucleus,GO:0051480//cytosolic calcium ion homeostasis,GO:0005509//calcium ion binding,"K14757//Endocrine and other factor-regulated calcium reabsorption;K14455//Cysteine and methionine metabolism;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis;Isoquinoline alkaloid biosynthesis;Phenylalanine metabolism;Arginine and proline metabolism;Metabolic pathways;Tropane, piperidine and pyridine alkaloid biosynthesis;Fat digestion and absorption;Tyrosine metabolism;Alanine, aspartate and glutamate metabolism"
79400,0,0,0,0,11,14,0,0,40,0,15,0,"NOX5;NADPH oxidase, EF-hand calcium binding domain 5",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0050663//cytokine secretion;GO:0042554//superoxide anion generation;GO:0008283//cell proliferation;GO:0055114//oxidation-reduction process;GO:0015992//proton transport;GO:0006915//apoptotic process;GO:0001525//angiogenesis;GO:0000910//cytokinesis;GO:0043012//regulation of fusion of sperm to egg plasma membrane;GO:0010155//regulation of proton transport;GO:0001935//endothelial cell proliferation,GO:0016175//superoxide-generating NADPH oxidase activity;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0015252//hydrogen ion channel activity;GO:0020037//heme binding;GO:0050661//NADP binding;GO:0050660//flavin adenine dinucleotide binding,K08008//Osteoclast differentiation;Phagosome;Leukocyte transendothelial migration
7941,110,0,0,0,14,0,24,61,15,0,0,0,"PLA2G7;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)",GO:0005737//cytoplasm;GO:0034362//low-density lipoprotein particle;GO:0005576//extracellular region,GO:0034441//plasma lipoprotein particle oxidation;GO:0034440//lipid oxidation;GO:0050729//positive regulation of inflammatory response;GO:0090026//positive regulation of monocyte chemotaxis;GO:0016042//lipid catabolic process;GO:0034374//low-density lipoprotein particle remodeling;GO:0044267//cellular protein metabolic process,GO:0005543//phospholipid binding;GO:0047499//calcium-independent phospholipase A2 activity;GO:0003847//1-alkyl-2-acetylglycerophosphocholine esterase activity,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
79411,0,0,0,21,4,0,0,0,8,0,0,0,"GLB1L;galactosidase, beta 1-like",GO:0005576//extracellular region,GO:0005975//carbohydrate metabolic process,GO:0004565//beta-galactosidase activity,K12309//Glycosaminoglycan degradation;Glycosphingolipid biosynthesis - ganglio series;Galactose metabolism;Metabolic pathways;Other glycan degradation;Lysosome;Sphingolipid metabolism
79412,0,0,70,0,21,17,0,45,16,11,77,0,KREMEN2;kringle containing transmembrane protein 2,GO:0016021//integral component of membrane,GO:0016055//Wnt signaling pathway,-,K01315//Staphylococcus aureus infection;Influenza A;Complement and coagulation cascades;Neuroactive ligand-receptor interaction
79413,4,0,0,0,0,31,0,0,21,0,0,0,"ZBED2;zinc finger, BED-type containing 2",-,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79414,0,0,0,0,0,0,0,0,0,3,0,0,LRFN3;leucine rich repeat and fibronectin type III domain containing 3,GO:0030424//axon;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0030425//dendrite;GO:0016021//integral component of membrane;GO:0045211//postsynaptic membrane,GO:0007155//cell adhesion,-,K07523//Axon guidance
79415,60,28,0,0,16,0,32,0,11,0,0,330,C17orf62;chromosome 17 open reading frame 62,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K03956//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;K09188//Lysine degradation
7942,0,0,0,0,0,21,17,84,16,0,0,0,TFEB;transcription factor EB,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007040//lysosome organization;GO:0006959//humoral immune response;GO:0006351//transcription, DNA-templated;GO:0006914//autophagy;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010508//positive regulation of autophagy;GO:0006355//regulation of transcription, DNA-templated;GO:0001892//embryonic placenta development",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding;GO:0046983//protein dimerization activity,-
79441,0,33,0,23,40,0,0,0,10,0,0,0,"HAUS3;HAUS augmin-like complex, subunit 3",GO:0005819//spindle;GO:0070652//HAUS complex;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0051297//centrosome organization;GO:0007067//mitotic nuclear division;GO:0051225//spindle assembly,-,K11447//Transcriptional misregulation in cancer
79442,1,0,0,0,0,0,43,0,53,0,0,0,LRRC2;leucine rich repeat containing 2,-,-,-,K01768//Purine metabolism;Meiosis - yeast
79443,0,10,0,2,58,5,0,30,31,144,5,256,FYCO1;FYVE and coiled-coil domain containing 1,GO:0016021//integral component of membrane;GO:0005770//late endosome;GO:0016020//membrane;GO:0005776//autophagic vacuole;GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle,GO:0072383//plus-end-directed vesicle transport along microtubule,GO:0046872//metal ion binding;GO:0005515//protein binding,K12482//Endocytosis;K12478//Tuberculosis;Phagosome;Endocytosis
79444,0,0,0,0,0,0,5,0,29,0,0,0,BIRC7;baculoviral IAP repeat containing 7,GO:0005794//Golgi apparatus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0010951//negative regulation of endopeptidase activity;GO:0042127//regulation of cell proliferation;GO:0007257//activation of JUN kinase activity;GO:0070247//regulation of natural killer cell apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination,GO:0019899//enzyme binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,K16061//Apoptosis;Pathways in cancer;Toxoplasmosis;Small cell lung cancer;Ubiquitin mediated proteolysis
79446,1,0,0,0,0,18,20,1,0,0,0,389,WDR25;WD repeat domain 25,-,-,-,K12816//Spliceosome
79447,0,0,0,9,6,48,33,1,7,0,1,0,PAGR1;PAXIP1 associated glutamate-rich protein 1,GO:0005634//nucleus;GO:0035097//histone methyltransferase complex,-,GO:0005515//protein binding,-
79465,0,0,0,0,0,0,0,0,33,0,0,0,ULBP3;UL16 binding protein 3,GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane,GO:0042267//natural killer cell mediated cytotoxicity;GO:0030101//natural killer cell activation;GO:0019882//antigen processing and presentation;GO:0016032//viral process;GO:0050776//regulation of immune response,GO:0046703//natural killer cell lectin-like receptor binding,K07986//Natural killer cell mediated cytotoxicity
79473,0,0,0,0,0,0,0,0,21,0,0,0,"OR52N1;olfactory receptor, family 52, subfamily N, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
795,0,0,0,0,0,0,25,0,0,0,0,0,S100G;S100 calcium binding protein G,GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane,-,GO:0005509//calcium ion binding;GO:0005499//vitamin D binding,K14734//Mineral absorption
79501,0,0,0,0,0,0,0,0,23,0,0,0,"OR4F5;olfactory receptor, family 4, subfamily F, member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
79541,0,0,0,0,0,0,0,0,5,0,1,0,"OR2A4;olfactory receptor, family 2, subfamily A, member 4",GO:0097431//mitotic spindle pole;GO:0090543//Flemming body;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0032154//cleavage furrow;GO:1990023//mitotic spindle midzone;GO:0055037//recycling endosome,GO:0032956//regulation of actin cytoskeleton organization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032467//positive regulation of cytokinesis;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
79567,52,0,0,1,0,0,54,0,52,0,15,0,"FAM65A;family with sequence similarity 65, member A",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,-,-,-
79568,0,0,0,6,0,0,0,0,11,0,0,0,C2orf47;chromosome 2 open reading frame 47,GO:0005739//mitochondrion,-,-,-
7957,0,0,0,4,0,0,27,44,26,0,0,0,"EPM2A;epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)",GO:0005886//plasma membrane;GO:0005844//polysome;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007399//nervous system development;GO:0046855//inositol phosphate dephosphorylation;GO:0005977//glycogen metabolic process;GO:0046959//habituation;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006914//autophagy;GO:0005978//glycogen biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,"GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:2001070//starch binding;GO:0004722//protein serine/threonine phosphatase activity;GO:0019203//carbohydrate phosphatase activity;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding",-
79570,0,0,0,0,0,0,23,93,4,0,13,0,NKAIN1;Na+/K+ transporting ATPase interacting 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
79571,0,34,0,13,59,0,0,0,25,162,1,0,GCC1;GRIP and coiled-coil domain containing 1,GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0000042//protein targeting to Golgi,GO:0005515//protein binding,K02084//Huntington's disease;Parkinson's disease;Tuberculosis;Legionellosis;Small cell lung cancer;Apoptosis;Amyotrophic lateral sclerosis (ALS);Alzheimer's disease;p53 signaling pathway
79572,0,0,0,20,3,42,0,0,129,0,0,0,ATP13A3;ATPase type 13A3,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006200//ATP catabolic process,GO:0019829//cation-transporting ATPase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,-
79573,14,0,0,0,0,45,33,0,9,42,0,0,TTC13;tetratricopeptide repeat domain 13,-,-,-,K09667//Other types of O-glycan biosynthesis;K09523//Protein processing in endoplasmic reticulum;Influenza A
79574,86,0,0,0,0,22,0,0,19,0,0,0,EPS8L3;EPS8-like 3,GO:0005737//cytoplasm,-,-,K07363//Leukocyte transendothelial migration;Chemokine signaling pathway;T cell receptor signaling pathway;K07364//Osteoclast differentiation;T cell receptor signaling pathway
79576,0,0,0,0,0,0,0,60,7,69,0,0,NKAP;NFKB activating protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0033077//T cell differentiation in thymus;GO:0030851//granulocyte differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046638//positive regulation of alpha-beta T cell differentiation;GO:0071425//hematopoietic stem cell proliferation;GO:0007219//Notch signaling pathway",GO:0031490//chromatin DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding,-
79577,0,3,1,24,143,35,0,0,50,0,0,0,CDC73;cell division cycle 73,GO:0016593//Cdc73/Paf1 complex;GO:0005634//nucleus,"GO:0045638//negative regulation of myeloid cell differentiation;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0010390//histone monoubiquitination;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006378//mRNA polyadenylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050680//negative regulation of epithelial cell proliferation;GO:0016055//Wnt signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033523//histone H2B ubiquitination;GO:0031648//protein destabilization;GO:0030177//positive regulation of Wnt signaling pathway;GO:0019827//stem cell maintenance;GO:0048147//negative regulation of fibroblast proliferation;GO:0001711//endodermal cell fate commitment",GO:0000993//RNA polymerase II core binding;GO:0005515//protein binding,-
79581,0,0,0,0,0,0,0,0,12,0,0,0,"SLC52A2;solute carrier family 52 (riboflavin transporter), member 2",GO:0005887//integral component of plasma membrane,GO:0009615//response to virus;GO:0032218//riboflavin transport,GO:0032217//riboflavin transporter activity;GO:0001618//virus receptor activity,K14620//Vitamin digestion and absorption
79582,0,1,1,6,50,29,0,0,53,0,0,135,SPAG16;sperm associated antigen 16,GO:0031514//motile cilium;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005930//axoneme,GO:0042384//cilium assembly;GO:0007283//spermatogenesis,GO:0019901//protein kinase binding,-
79583,196,0,0,0,0,12,0,0,23,0,13,0,TMEM231;transmembrane protein 231,GO:0035869//ciliary transition zone;GO:0016021//integral component of membrane;GO:0036038//TCTN-B9D complex;GO:0060170//ciliary membrane,GO:0042384//cilium assembly;GO:0007224//smoothened signaling pathway,-,K12460//Neurotrophin signaling pathway
79585,0,0,0,0,0,0,0,44,0,81,1,0,CORO7;coronin 7,GO:0005802//trans-Golgi network;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005829//cytosol;GO:0015629//actin cytoskeleton,GO:0030041//actin filament polymerization;GO:0030036//actin cytoskeleton organization;GO:0006895//Golgi to endosome transport;GO:0015031//protein transport,GO:0003779//actin binding;GO:0051015//actin filament binding;GO:0005515//protein binding,K13882//Tuberculosis;Phagosome
79586,0,0,0,0,0,0,0,21,54,1,0,0,CHPF;chondroitin polymerizing factor,GO:0000139//Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0050510//N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity;GO:0047238//glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity,K00747//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways
79587,65,37,0,33,25,0,0,0,34,0,0,0,"CARS2;cysteinyl-tRNA synthetase 2, mitochondrial (putative)",GO:0005829//cytosol;GO:0005759//mitochondrial matrix,GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006423//cysteinyl-tRNA aminoacylation,GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0004817//cysteine-tRNA ligase activity,K01883//Arginine and proline metabolism;Ribosome;DNA replication;Metabolic pathways;Aminoacyl-tRNA biosynthesis
79589,0,0,0,1,0,8,0,0,16,0,0,0,"RNF128;ring finger protein 128, E3 ubiquitin protein ligase",GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0005770//late endosome;GO:0016021//integral component of membrane;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm,GO:0042036//negative regulation of cytokine biosynthetic process;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
79590,0,36,0,18,3,0,0,0,31,0,0,0,MRPL24;mitochondrial ribosomal protein L24,GO:0005840//ribosome;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
79591,0,0,0,5,2,10,15,0,10,0,4,0,C10orf76;chromosome 10 open reading frame 76,GO:0016021//integral component of membrane,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K15187//Transcriptional misregulation in cancer;K11447//Transcriptional misregulation in cancer;K14443//RNA degradation
79594,0,1,0,0,21,12,29,72,11,0,17,0,MUL1;mitochondrial E3 ubiquitin protein ligase 1,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005777//peroxisome;GO:0005737//cytoplasm;GO:0031307//integral component of mitochondrial outer membrane;GO:0005634//nucleus,GO:0051898//negative regulation of protein kinase B signaling;GO:0007257//activation of JUN kinase activity;GO:0016925//protein sumoylation;GO:1901028//regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0045824//negative regulation of innate immune response;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0000266//mitochondrial fission;GO:0071360//cellular response to exogenous dsRNA;GO:0071650//negative regulation of chemokine (C-C motif) ligand 5 production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0090141//positive regulation of mitochondrial fission;GO:0050689//negative regulation of defense response to virus by host;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0010637//negative regulation of mitochondrial fusion;GO:0030308//negative regulation of cell growth;GO:0051646//mitochondrion localization;GO:0050821//protein stabilization;GO:0016567//protein ubiquitination;GO:0033235//positive regulation of protein sumoylation,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0004871//signal transducer activity;GO:0008270//zinc ion binding;GO:0019789//SUMO ligase activity,-
79595,0,33,1,0,1,12,33,3,60,0,10,0,"SAP130;Sin3A-associated protein, 130kDa",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0030914//STAGA complex,"GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity,K10955//Vibrio cholerae infection;Amoebiasis
79596,0,5,44,31,11,0,0,0,67,0,3,0,RNF219;ring finger protein 219,-,-,GO:0008270//zinc ion binding,-
79598,0,0,0,0,37,0,0,0,65,0,0,0,CEP97;centrosomal protein 97kDa,GO:0005815//microtubule organizing center;GO:0043234//protein complex;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0030030//cell projection organization,GO:0005515//protein binding;GO:0005516//calmodulin binding,K11092//Spliceosome
796,0,0,0,0,0,0,0,0,13,0,21,0,CALCA;calcitonin-related polypeptide alpha,GO:0005634//nucleus;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0043195//terminal bouton;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0045986//negative regulation of smooth muscle contraction;GO:0001944//vasculature development;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0002548//monocyte chemotaxis;GO:0032757//positive regulation of interleukin-8 production;GO:0045671//negative regulation of osteoclast differentiation;GO:0051482//positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0007631//feeding behavior;GO:0031623//receptor internalization;GO:0045779//negative regulation of bone resorption;GO:0007568//aging;GO:0007566//embryo implantation;GO:0032147//activation of protein kinase activity;GO:0001976//neurological system process involved in regulation of systemic arterial blood pressure;GO:0051480//cytosolic calcium ion homeostasis;GO:0007159//leukocyte cell-cell adhesion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0001935//endothelial cell proliferation;GO:0002031//G-protein coupled receptor internalization;GO:0048265//response to pain;GO:0002027//regulation of heart rate;GO:0006468//protein phosphorylation;GO:0001984//vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure;GO:0045778//positive regulation of ossification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0008217//regulation of blood pressure;GO:0045909//positive regulation of vasodilation;GO:0045776//negative regulation of blood pressure;GO:0043542//endothelial cell migration;GO:0006954//inflammatory response;GO:0045762//positive regulation of adenylate cyclase activity;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007218//neuropeptide signaling pathway;GO:0009408//response to heat;GO:0050727//regulation of inflammatory response;GO:0007190//activation of adenylate cyclase activity;GO:0010523//negative regulation of calcium ion transport into cytosol;GO:0031645//negative regulation of neurological system process;GO:0045651//positive regulation of macrophage differentiation;GO:0032730//positive regulation of interleukin-1 alpha production;GO:0030279//negative regulation of ossification;GO:0007267//cell-cell signaling",GO:0031716//calcitonin receptor binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005179//hormone activity;GO:0005102//receptor binding;GO:0032403//protein complex binding,-
79600,50,0,0,8,1,14,0,0,22,0,0,0,TCTN1;tectonic family member 1,GO:0005615//extracellular space;GO:0016020//membrane;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0036038//TCTN-B9D complex,GO:0001841//neural tube formation;GO:0021956//central nervous system interneuron axonogenesis;GO:0008589//regulation of smoothened signaling pathway;GO:0021537//telencephalon development;GO:0001701//in utero embryonic development;GO:0060271//cilium morphogenesis;GO:0021523//somatic motor neuron differentiation;GO:0021904//dorsal/ventral neural tube patterning,-,-
79602,0,0,1,12,57,0,27,0,24,0,0,0,ADIPOR2;adiponectin receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007565//female pregnancy;GO:0019395//fatty acid oxidation;GO:0033211//adiponectin-activated signaling pathway;GO:0007507//heart development;GO:0009755//hormone-mediated signaling pathway;GO:0007584//response to nutrient;GO:0046326//positive regulation of glucose import;GO:0030308//negative regulation of cell growth,GO:0004872//receptor activity;GO:0055100//adiponectin binding;GO:0042562//hormone binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity,K07297//Adipocytokine signaling pathway
79603,0,0,1,0,1,0,0,0,28,0,7,0,CERS4;ceramide synthase 4,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0046513//ceramide biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process,GO:0003677//DNA binding;GO:0050291//sphingosine N-acyltransferase activity,K04710//Sphingolipid metabolism;Metabolic pathways
79605,69,0,0,0,8,0,0,0,21,0,0,0,PGBD5;piggyBac transposable element derived 5,GO:0016021//integral component of membrane,-,-,-
79607,0,67,0,0,32,13,0,0,65,0,64,0,"FAM118B;family with sequence similarity 118, member B",-,-,-,-
79608,0,21,31,4,54,0,9,0,30,0,52,0,RIC3;RIC3 acetylcholine receptor chaperone,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0043623//cellular protein complex assembly;GO:0006457//protein folding;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007271//synaptic transmission, cholinergic",GO:0033130//acetylcholine receptor binding;GO:0044183//protein binding involved in protein folding,-
79609,0,0,0,4,12,0,0,0,16,0,0,0,VCPKMT;valosin containing protein lysine (K) methyltransferase,GO:0005737//cytoplasm,GO:0018023//peptidyl-lysine trimethylation,GO:0005515//protein binding;GO:0016279//protein-lysine N-methyltransferase activity,-
79611,0,0,1,12,11,16,5,0,40,0,17,0,ACSS3;acyl-CoA synthetase short-chain family member 3,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0003987//acetate-CoA ligase activity,K01908//Propanoate metabolism;Metabolic pathways;RNA degradation
79612,0,0,0,0,19,0,63,0,20,0,0,0,"NAA16;N(alpha)-acetyltransferase 16, NatA auxiliary subunit",GO:0031415//NatA complex;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization;GO:0006474//N-terminal protein amino acid acetylation;GO:0045893//positive regulation of transcription, DNA-templated",GO:0043022//ribosome binding;GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0005515//protein binding,-
79613,0,0,0,10,14,31,0,0,1,0,32,0,TANGO6;transport and golgi organization 6 homolog (Drosophila),GO:0016021//integral component of membrane,-,-,-
79616,0,0,0,0,0,0,0,1,17,0,0,0,CCNJL;cyclin J-like,GO:0005634//nucleus,-,-,-
79618,0,0,0,12,51,33,0,0,17,0,0,0,HMBOX1;homeobox containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding,K08036//Maturity onset diabetes of the young
79621,0,1,0,0,0,0,20,37,16,255,0,141,"RNASEH2B;ribonuclease H2, subunit B",GO:0032299//ribonuclease H2 complex;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0010629//negative regulation of gene expression;GO:0001701//in utero embryonic development;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006401//RNA catabolic process;GO:0009259//ribonucleotide metabolic process;GO:0048146//positive regulation of fibroblast proliferation;GO:2000001//regulation of DNA damage checkpoint",GO:0004523//RNA-DNA hybrid ribonuclease activity,K10744//DNA replication
79622,0,23,0,13,2,0,0,0,0,0,0,0,SNRNP25;small nuclear ribonucleoprotein 25kDa (U11/U12),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005689//U12-type spliceosomal complex;GO:0045171//intercellular bridge;GO:0005730//nucleolus,GO:0008380//RNA splicing;GO:0006397//mRNA processing,-,-
79623,0,0,0,0,2,46,0,0,21,0,6,0,GALNT14;polypeptide N-acetylgalactosaminyltransferase 14,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity;GO:0046872//metal ion binding;GO:0030246//carbohydrate binding,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
79624,0,0,0,10,23,0,10,0,1,0,0,300,C6orf211;chromosome 6 open reading frame 211,-,-,-,-
79625,0,0,0,0,0,37,0,0,0,0,0,0,NDNF;neuron-derived neurotrophic factor,GO:0005576//extracellular region;GO:0031012//extracellular matrix,GO:0010976//positive regulation of neuron projection development;GO:0010811//positive regulation of cell-substrate adhesion;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0001764//neuron migration;GO:0043524//negative regulation of neuron apoptotic process;GO:0016049//cell growth;GO:0030198//extracellular matrix organization,GO:0005539//glycosaminoglycan binding;GO:0008201//heparin binding,-
79626,0,0,0,0,7,0,0,0,0,0,0,0,"TNFAIP8L2;tumor necrosis factor, alpha-induced protein 8-like 2",GO:0005737//cytoplasm,GO:0050728//negative regulation of inflammatory response;GO:0050868//negative regulation of T cell activation;GO:0045087//innate immune response,GO:0005515//protein binding,-
79627,0,0,0,18,7,0,0,0,21,0,0,0,OGFRL1;opioid growth factor receptor-like 1,GO:0016020//membrane,-,GO:0004872//receptor activity,-
79628,0,0,0,0,0,36,86,0,158,133,0,0,SH3TC2;SH3 domain and tetratricopeptide repeats 2,GO:0055037//recycling endosome;GO:0031410//cytoplasmic vesicle;GO:0005886//plasma membrane,GO:0032287//peripheral nervous system myelin maintenance;GO:1901184//regulation of ERBB signaling pathway;GO:0008219//cell death;GO:0033157//regulation of intracellular protein transport,-,K11447//Transcriptional misregulation in cancer
79629,0,1,0,0,1,0,0,0,14,0,0,0,OCEL1;occludin/ELL domain containing 1,-,-,-,-
79631,14,0,1,14,83,0,18,0,77,0,11,0,EFTUD1;elongation factor Tu GTP binding domain containing 1,-,GO:0042256//mature ribosome assembly;GO:0006184//GTP catabolic process;GO:0006414//translational elongation,GO:0043022//ribosome binding;GO:0003746//translation elongation factor activity;GO:0003924//GTPase activity;GO:0005525//GTP binding,K14536//Ribosome biogenesis in eukaryotes
79632,0,0,0,0,0,0,19,4,21,0,0,0,"FAM184A;family with sequence similarity 184, member A",GO:0005615//extracellular space,-,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K12478//Tuberculosis;Phagosome;Endocytosis
79633,207,0,0,0,14,27,41,0,169,130,0,0,FAT4;FAT atypical cadherin 4,GO:0045177//apical part of cell;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0048565//digestive tract development;GO:0003007//heart morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0022008//neurogenesis;GO:0072307//regulation of metanephric nephron tubule epithelial cell differentiation;GO:0043931//ossification involved in bone maturation;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035329//hippo signaling;GO:0021987//cerebral cortex development;GO:0060122//inner ear receptor stereocilium organization;GO:0007009//plasma membrane organization,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
79634,0,0,0,0,23,38,0,0,0,0,7,0,SCRN3;secernin 3,-,GO:0006508//proteolysis,GO:0016805//dipeptidase activity,-
79635,0,0,0,0,9,0,0,0,30,0,0,0,CCDC121;coiled-coil domain containing 121,-,-,-,-
79637,0,86,22,54,64,0,0,43,72,0,30,0,ARMC7;armadillo repeat containing 7,GO:0005737//cytoplasm,-,-,K10610//Ubiquitin mediated proteolysis;Nucleotide excision repair
79640,0,0,0,0,0,0,28,0,16,0,0,0,C22orf46;chromosome 22 open reading frame 46,GO:0005576//extracellular region,-,-,-
79641,0,0,0,9,15,0,1,5,10,0,7,0,ROGDI;rogdi homolog (Drosophila),GO:0005622//intracellular;GO:0005635//nuclear envelope,GO:0030097//hemopoiesis;GO:0008284//positive regulation of cell proliferation,-,-
79642,40,0,0,17,0,1,0,135,13,0,15,0,"ARSJ;arylsulfatase family, member J",GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region,GO:0044281//small molecule metabolic process;GO:0044267//cellular protein metabolic process;GO:0006687//glycosphingolipid metabolic process;GO:0043687//post-translational protein modification;GO:0006665//sphingolipid metabolic process,GO:0004065//arylsulfatase activity;GO:0046872//metal ion binding,-
79643,0,1,0,0,0,35,0,41,12,0,10,0,CHMP6;charged multivesicular body protein 6,GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0031902//late endosome membrane,GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0019058//viral life cycle;GO:0016032//viral process,GO:0005515//protein binding;GO:0047485//protein N-terminus binding,K12195//Endocytosis
79644,0,0,0,0,0,14,17,0,9,324,1,0,SRD5A3;steroid 5 alpha-reductase 3,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006489//dolichyl diphosphate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0055114//oxidation-reduction process;GO:0008202//steroid metabolic process;GO:0019348//dolichol metabolic process;GO:0016095//polyprenol catabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006702//androgen biosynthetic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0043687//post-translational protein modification,"GO:0016628//oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0003865//3-oxo-5-alpha-steroid 4-dehydrogenase activity;GO:0047751//cholestenone 5-alpha-reductase activity",K12345//Steroid hormone biosynthesis
79645,0,0,0,0,6,33,0,0,0,0,0,0,EFCAB1;EF-hand calcium binding domain 1,-,-,GO:0005509//calcium ion binding,K06268//Tuberculosis;Long-term potentiation;Axon guidance;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Apoptosis;Glutamatergic synapse;Amphetamine addiction;Oocyte meiosis;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;Calcium signaling pathway;B cell receptor signaling pathway;HTLV-I infection;VEGF signaling pathway;Osteoclast differentiation;Alzheimer's disease;K08328//Olfactory transduction;Phototransduction;K01852//Biosynthesis of secondary metabolites;Metabolic pathways;Steroid biosynthesis
79646,0,0,2,40,304,0,31,0,16,0,1,0,PANK3;pantothenate kinase 3,GO:0005737//cytoplasm,GO:0016310//phosphorylation;GO:0015937//coenzyme A biosynthetic process,GO:0005524//ATP binding;GO:0004594//pantothenate kinase activity,K09680//Metabolic pathways;Pantothenate and CoA biosynthesis
79647,1,0,1,17,131,0,0,1,9,0,0,0,AKIRIN1;akirin 1,GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005730//nucleolus,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption
79648,0,11,0,0,9,0,18,0,80,0,26,0,MCPH1;microcephalin 1,GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm,GO:0021987//cerebral cortex development;GO:0000278//mitotic cell cycle,GO:0042802//identical protein binding;GO:0005515//protein binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption
79649,0,0,0,0,0,34,55,191,24,0,3,0,MAP7D3;MAP7 domain containing 3,GO:0005819//spindle;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0016020//membrane;GO:0005730//nucleolus,GO:0000226//microtubule cytoskeleton organization,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
7965,0,76,0,50,87,0,0,0,3,0,27,0,AIMP2;aminoacyl tRNA synthetase complex-interacting multifunctional protein 2,GO:0005634//nucleus;GO:0005829//cytosol;GO:0016020//membrane,GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0031398//positive regulation of protein ubiquitination;GO:0006915//apoptotic process;GO:0060510//Type II pneumocyte differentiation,GO:0005515//protein binding,-
79650,0,0,0,0,0,1,0,0,9,0,0,0,USB1;U6 snRNA biogenesis 1,GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0034477//U6 snRNA 3'-end processing;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic",GO:0000175//3'-5'-exoribonuclease activity,-
79651,0,0,0,0,0,36,0,7,11,0,0,0,RHBDF2;rhomboid 5 homolog 2 (Drosophila),GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050709//negative regulation of protein secretion;GO:0015031//protein transport;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0019838//growth factor binding,K02857//Dorso-ventral axis formation
79652,0,0,0,0,0,26,34,0,34,118,20,0,TMEM204;transmembrane protein 204,GO:0005912//adherens junction;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006950//response to stress;GO:0051145//smooth muscle cell differentiation;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001945//lymph vessel development,-,-
79654,0,0,0,0,24,1,0,37,26,0,40,0,HECTD3;HECT domain containing E3 ubiquitin protein ligase 3,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0019905//syntaxin binding,-
79657,0,0,0,13,11,1,0,0,79,0,0,0,RPAP3;RNA polymerase II associated protein 3,-,-,GO:0005515//protein binding,K09553//Prion diseases
79658,0,0,0,0,6,24,0,56,26,0,0,0,ARHGAP10;Rho GTPase activating protein 10,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,GO:0007264//small GTPase mediated signal transduction;GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007010//cytoskeleton organization;GO:0043066//negative regulation of apoptotic process,GO:0005515//protein binding;GO:0005100//Rho GTPase activator activity,K13736//Bacterial invasion of epithelial cells
79659,13,1,0,19,150,12,83,97,120,0,0,0,"DYNC2H1;dynein, cytoplasmic 2, heavy chain 1",GO:0005874//microtubule;GO:0005930//axoneme;GO:0005829//cytosol;GO:0045177//apical part of cell;GO:0030286//dynein complex;GO:0031512//motile primary cilium;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0045880//positive regulation of smoothened signaling pathway;GO:0030900//forebrain development;GO:0007030//Golgi organization;GO:0042384//cilium assembly;GO:0035721//intraciliary retrograde transport;GO:0021522//spinal cord motor neuron differentiation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0009953//dorsal/ventral pattern formation;GO:0007368//determination of left/right symmetry;GO:0006200//ATP catabolic process;GO:0030326//embryonic limb morphogenesis;GO:0016485//protein processing;GO:0008105//asymmetric protein localization,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003774//motor activity;GO:0003777//microtubule motor activity,K10414//Salmonella infection;Phagosome;Vasopressin-regulated water reabsorption
79660,88,29,0,23,67,38,0,0,94,0,16,0,"PPP1R3B;protein phosphatase 1, regulatory subunit 3B",GO:0000164//protein phosphatase type 1 complex;GO:0042587//glycogen granule;GO:0043231//intracellular membrane-bounded organelle,GO:0005981//regulation of glycogen catabolic process;GO:0005979//regulation of glycogen biosynthetic process;GO:0050790//regulation of catalytic activity;GO:0005977//glycogen metabolic process,GO:0019899//enzyme binding;GO:0019888//protein phosphatase regulator activity,K07189//Insulin signaling pathway
79661,0,0,1,7,0,0,0,0,24,0,13,0,NEIL1;nei endonuclease VIII-like 1 (E. coli),GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005694//chromosome,"GO:0032074//negative regulation of nuclease activity;GO:0006979//response to oxidative stress;GO:0006289//nucleotide-excision repair;GO:0000737//DNA catabolic process, endonucleolytic;GO:0006284//base-excision repair","GO:0003684//damaged DNA binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0008022//protein C-terminus binding;GO:0019104//DNA N-glycosylase activity;GO:0008270//zinc ion binding;GO:0016798//hydrolase activity, acting on glycosyl bonds",K10567//Base excision repair
79663,0,0,0,0,0,24,0,0,30,70,0,0,HSPBAP1;HSPB (heat shock 27kDa) associated protein 1,GO:0005737//cytoplasm,-,-,-
79664,0,27,0,38,31,0,47,54,36,0,6,0,ICE2;interactor of little elongator complex ELL subunit 2,GO:0015030//Cajal body;GO:0008023//transcription elongation factor complex;GO:0035327//transcriptionally active chromatin,GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0042796//snRNA transcription from RNA polymerase III promoter;GO:0045945//positive regulation of transcription from RNA polymerase III promoter,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
79665,0,68,26,24,25,28,0,0,19,0,0,0,DHX40;DEAH (Asp-Glu-Ala-His) box polypeptide 40,-,GO:0006200//ATP catabolic process,GO:0008026//ATP-dependent helicase activity;GO:0003676//nucleic acid binding;GO:0005524//ATP binding,K12818//Spliceosome
79666,0,0,0,0,36,60,10,0,3,126,0,1,"PLEKHF2;pleckstrin homology domain containing, family F (with FYVE domain) member 2",GO:0030133//transport vesicle;GO:0031901//early endosome membrane;GO:0005783//endoplasmic reticulum,GO:0015031//protein transport,GO:0005515//protein binding;GO:0046872//metal ion binding,-
79668,0,134,9,76,155,50,33,109,54,0,108,0,"PARP8;poly (ADP-ribose) polymerase family, member 8",GO:0005622//intracellular,GO:0008152//metabolic process,GO:0003950//NAD+ ADP-ribosyltransferase activity,-
79669,0,0,0,0,0,19,0,0,8,0,6,0,C3orf52;chromosome 3 open reading frame 52,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,-,-,-
79670,0,66,2,82,258,0,23,0,127,0,0,0,"ZCCHC6;zinc finger, CCHC domain containing 6",-,GO:0031123//RNA 3'-end processing;GO:0071044//histone mRNA catabolic process,GO:0008270//zinc ion binding;GO:0050265//RNA uridylyltransferase activity;GO:0044822//poly(A) RNA binding,-
79671,0,0,0,0,0,0,35,52,14,28,17,0,NLRX1;NLR family member X1,GO:0005741//mitochondrial outer membrane,GO:0050728//negative regulation of inflammatory response;GO:0045824//negative regulation of innate immune response;GO:0032688//negative regulation of interferon-beta production;GO:0039536//negative regulation of RIG-I signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0016032//viral process;GO:0045087//innate immune response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032715//negative regulation of interleukin-6 production,GO:0005515//protein binding;GO:0005524//ATP binding,K12653//RIG-I-like receptor signaling pathway;Influenza A
79672,0,0,0,0,9,19,0,114,17,99,0,0,FN3KRP;fructosamine 3 kinase related protein,-,GO:0016310//phosphorylation,GO:0016301//kinase activity,-
79673,0,31,0,9,0,24,0,0,38,0,0,0,ZNF329;zinc finger protein 329,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79674,0,0,0,17,0,33,0,0,46,0,14,0,VEPH1;ventricular zone expressed PH domain-containing 1,GO:0005886//plasma membrane,-,-,-
79675,0,0,0,0,0,0,14,0,27,0,0,0,FASTKD1;FAST kinase domains 1,GO:0005739//mitochondrion,GO:0045333//cellular respiration;GO:0006468//protein phosphorylation,GO:0044822//poly(A) RNA binding;GO:0004672//protein kinase activity,-
79676,95,25,62,2,11,0,0,0,12,0,8,0,OGFOD2;2-oxoglutarate and iron-dependent oxygenase domain containing 2,-,GO:0055114//oxidation-reduction process,"GO:0031418//L-ascorbic acid binding;GO:0005506//iron ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",K05656//ABC transporters;Lysosome;K00473//Lysine degradation
79677,0,0,0,12,0,13,21,0,22,248,7,0,SMC6;structural maintenance of chromosomes 6,"GO:0000781//chromosome, telomeric region;GO:0005634//nucleus;GO:0030915//Smc5-Smc6 complex;GO:0005730//nucleolus;GO:0016605//PML body;GO:0005622//intracellular",GO:0090398//cellular senescence;GO:0000722//telomere maintenance via recombination;GO:0000724//double-strand break repair via homologous recombination,GO:0005524//ATP binding;GO:0005515//protein binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
79679,1,0,0,0,0,0,0,0,6,219,4,0,VTCN1;V-set domain containing T cell activation inhibitor 1,GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,GO:0002376//immune system process;GO:0072643//interferon-gamma secretion;GO:0001562//response to protozoan;GO:0050868//negative regulation of T cell activation;GO:0042102//positive regulation of T cell proliferation;GO:0072602//interleukin-4 secretion,GO:0005102//receptor binding,-
79680,87,32,1,0,26,12,43,0,18,0,12,1,C22orf29;chromosome 22 open reading frame 29,GO:0005739//mitochondrion,GO:0051881//regulation of mitochondrial membrane potential;GO:0097345//mitochondrial outer membrane permeabilization,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;K11447//Transcriptional misregulation in cancer
79682,0,0,0,15,13,0,46,0,4,0,2,0,CENPU;centromere protein U,GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center,"GO:0043009//chordate embryonic development;GO:0016032//viral process;GO:0006334//nucleosome assembly;GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0006355//regulation of transcription, DNA-templated;GO:0034080//CENP-A containing nucleosome assembly",-,-
79683,24,0,0,5,1,0,0,0,15,0,0,0,"ZDHHC14;zinc finger, DHHC-type containing 14",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
79684,0,0,0,0,18,0,0,0,0,0,0,0,MSANTD2;Myb/SANT-like DNA-binding domain containing 2,-,-,-,-
79685,0,8,0,18,203,48,34,0,44,0,0,0,SAP30L;SAP30-like,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79686,0,1,0,0,0,0,0,0,12,0,5,0,LINC00341;long intergenic non-protein coding RNA 341,-,-,-,-
79689,0,40,0,51,67,7,37,0,2,0,0,0,STEAP4;STEAP family member 4,GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0055072//iron ion homeostasis;GO:0015677//copper ion import;GO:0055114//oxidation-reduction process;GO:0045444//fat cell differentiation,GO:0046872//metal ion binding,K14738//Mineral absorption
79690,0,0,0,0,0,16,0,1,7,83,0,0,GAL3ST4;galactose-3-O-sulfotransferase 4,GO:0070062//extracellular vesicular exosome;GO:0032580//Golgi cisterna membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0009100//glycoprotein metabolic process;GO:0006790//sulfur compound metabolic process;GO:0007267//cell-cell signaling;GO:0030166//proteoglycan biosynthetic process;GO:0009311//oligosaccharide metabolic process,GO:0050698//proteoglycan sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding;GO:0001733//galactosylceramide sulfotransferase activity,-
79691,0,0,1,18,27,1,3,0,41,0,0,285,QTRTD1;queuine tRNA-ribosyltransferase domain containing 1,GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0008616//queuosine biosynthetic process,GO:0008270//zinc ion binding;GO:0008479//queuine tRNA-ribosyltransferase activity,-
79692,6,26,0,23,50,34,0,72,60,224,0,0,ZNF322;zinc finger protein 322,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79693,0,133,18,79,152,0,0,775,112,210,344,0,YRDC;yrdC N(6)-threonylcarbamoyltransferase domain containing,GO:0016020//membrane;GO:0005739//mitochondrion,GO:0051051//negative regulation of transport,GO:0003725//double-stranded RNA binding,K03019//Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Cytosolic DNA-sensing pathway;Metabolic pathways
79694,72,0,0,0,0,0,0,60,53,0,3,0,"MANEA;mannosidase, endo-alpha",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification,"GO:0004569//glycoprotein endo-alpha-1,2-mannosidase activity",-
79695,0,0,0,0,14,18,0,52,1,0,6,1,GALNT12;polypeptide N-acetylgalactosaminyltransferase 12,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification,GO:0030246//carbohydrate binding;GO:0046872//metal ion binding;GO:0004653//polypeptide N-acetylgalactosaminyltransferase activity,K00710//Metabolic pathways;Mucin type O-Glycan biosynthesis
79696,0,0,0,0,0,1,21,0,24,0,23,0,"ZC2HC1C;zinc finger, C2HC-type containing 1C",-,-,GO:0046872//metal ion binding,-
79697,93,0,0,9,1,0,0,0,0,0,0,0,C14orf169;chromosome 14 open reading frame 169,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0045668//negative regulation of osteoblast differentiation;GO:0070544//histone H3-K36 demethylation;GO:0034720//histone H3-K4 demethylation;GO:0055114//oxidation-reduction process","GO:0032453//histone demethylase activity (H3-K4 specific);GO:0051864//histone demethylase activity (H3-K36 specific);GO:0005506//iron ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005515//protein binding",-
79698,118,0,0,0,0,0,19,0,28,0,0,0,"ZMAT4;zinc finger, matrin-type 4",GO:0005634//nucleus,-,GO:0003677//DNA binding;GO:0008270//zinc ion binding,K10137//p53 signaling pathway
79699,24,35,0,8,117,0,9,36,42,0,0,0,"ZYG11B;zyg-11 family member B, cell cycle regulator",-,-,-,-
797,0,0,0,0,0,0,13,159,0,0,1,0,CALCB;calcitonin-related polypeptide beta,GO:0005576//extracellular region,GO:0006874//cellular calcium ion homeostasis;GO:0007165//signal transduction,GO:0005184//neuropeptide hormone activity,-
79701,0,0,0,0,48,0,20,28,54,1,4,0,OGFOD3;2-oxoglutarate and iron-dependent oxygenase domain containing 3,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process,"GO:0005506//iron ion binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0031418//L-ascorbic acid binding",K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79705,0,5,22,16,53,26,51,112,41,133,32,2,LRRK1;leucine-rich repeat kinase 1,GO:0005737//cytoplasm;GO:0005739//mitochondrion,GO:0007264//small GTPase mediated signal transduction;GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0005525//GTP binding,-
79706,0,0,0,1,0,0,0,0,0,0,0,0,PRKRIP1;PRKR interacting protein 1 (IL11 inducible),GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0042326//negative regulation of phosphorylation;GO:0003014//renal system process;GO:0006469//negative regulation of protein kinase activity,GO:0004860//protein kinase inhibitor activity;GO:0019901//protein kinase binding;GO:0003725//double-stranded RNA binding,-
79707,0,0,0,18,44,59,0,12,116,0,2,336,NOL9;nucleolar protein 9,GO:0016020//membrane;GO:0005730//nucleolus,GO:0016310//phosphorylation;GO:0000460//maturation of 5.8S rRNA,GO:0003723//RNA binding;GO:0051731//polynucleotide 5'-hydroxyl-kinase activity;GO:0005524//ATP binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
79709,84,0,0,0,0,0,50,0,74,0,2,6,COLGALT1;collagen beta(1-O)galactosyltransferase 1,GO:0005788//endoplasmic reticulum lumen;GO:0016020//membrane,GO:0030198//extracellular matrix organization;GO:0009103//lipopolysaccharide biosynthetic process,GO:0050211//procollagen galactosyltransferase activity,K11703//Other types of O-glycan biosynthesis;Lysine degradation
79710,0,52,1,11,100,1,17,0,6,0,7,0,MORC4;MORC family CW-type zinc finger 4,GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0005515//protein binding,-
79711,0,0,0,0,0,21,0,50,22,0,5,3,IPO4;importin 4,GO:0043234//protein complex;GO:0000790//nuclear chromatin;GO:0005643//nuclear pore;GO:0005737//cytoplasm;GO:0016020//membrane,GO:0015031//protein transport;GO:0006886//intracellular protein transport;GO:0006336//DNA replication-independent nucleosome assembly;GO:0006335//DNA replication-dependent nucleosome assembly,GO:0008536//Ran GTPase binding,-
79712,0,13,0,15,44,1,0,0,41,0,0,0,GTDC1;glycosyltransferase-like domain containing 1,-,GO:0009058//biosynthetic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
79713,0,0,0,0,0,0,0,83,16,0,0,0,IGFLR1;IGF-like family receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,GO:0005515//protein binding,-
79714,0,30,0,11,0,0,0,0,0,0,0,0,CCDC51;coiled-coil domain containing 51,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,-
79717,0,54,0,32,142,0,0,0,42,0,4,0,PPCS;phosphopantothenoylcysteine synthetase,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0009108//coenzyme biosynthetic process;GO:0015939//pantothenate metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0006766//vitamin metabolic process,GO:0004632//phosphopantothenate--cysteine ligase activity,K01922//Metabolic pathways;Pantothenate and CoA biosynthesis
79718,0,65,2,87,98,10,0,0,27,0,0,0,TBL1XR1;transducin (beta)-like 1 X-linked receptor 1,GO:0005876//spindle microtubule;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0017053//transcriptional repressor complex,"GO:0044281//small molecule metabolic process;GO:0016568//chromatin modification;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007219//Notch signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060070//canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0047485//protein N-terminus binding;GO:0008013//beta-catenin binding;GO:0003714//transcription corepressor activity;GO:0042393//histone binding;GO:0005515//protein binding,K04508//Wnt signaling pathway
79719,51,0,0,37,153,0,58,0,12,0,1,0,AAGAB;alpha- and gamma-adaptin binding protein,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0015031//protein transport,-,-
79720,0,1,29,0,21,10,34,0,28,0,6,0,VPS37B;vacuolar protein sorting 37 homolog B (S. cerevisiae),GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex;GO:0070062//extracellular vesicular exosome;GO:0030496//midbody;GO:0010008//endosome membrane,GO:0061024//membrane organization;GO:0015031//protein transport;GO:0019068//virion assembly;GO:0016197//endosomal transport;GO:0075733//intracellular transport of virus;GO:0019082//viral protein processing;GO:0019058//viral life cycle;GO:0016032//viral process,GO:0005515//protein binding,K12185//Endocytosis
79722,0,0,0,0,0,20,34,22,56,0,0,0,ANKRD55;ankyrin repeat domain 55,-,-,-,-
79723,0,1,0,87,77,11,0,0,45,0,0,0,SUV39H2;suppressor of variegation 3-9 homolog 2 (Drosophila),"GO:0005720//nuclear heterochromatin;GO:0000785//chromatin;GO:0000775//chromosome, centromeric region","GO:0006333//chromatin assembly or disassembly;GO:0036123//histone H3-K9 dimethylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0007140//male meiosis;GO:0030154//cell differentiation;GO:0036124//histone H3-K9 trimethylation;GO:0048511//rhythmic process;GO:0042754//negative regulation of circadian rhythm",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific),K11419//Lysine degradation
79724,15,0,0,4,4,0,0,0,5,0,0,40,ZNF768;zinc finger protein 768,"GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
79725,0,11,0,10,0,1,0,0,27,0,0,0,THAP9;THAP domain containing 9,-,"GO:0006310//DNA recombination;GO:0015074//DNA integration;GO:0006313//transposition, DNA-mediated",GO:0004803//transposase activity;GO:0016740//transferase activity;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding,K14575//Ribosome biogenesis in eukaryotes;K12882//Spliceosome;mRNA surveillance pathway;RNA transport;K14613//Mineral absorption;Vitamin digestion and absorption
79726,30,0,0,4,2,12,0,3,11,0,35,0,WDR59;WD repeat domain 59,-,-,-,-
79727,0,0,0,0,0,24,0,17,36,0,0,0,LIN28A;lin-28 homolog A (C. elegans),GO:0000932//cytoplasmic mRNA processing body;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0031054//pre-miRNA processing;GO:0019827//stem cell maintenance;GO:0045686//negative regulation of glial cell differentiation;GO:0007281//germ cell development;GO:0045727//positive regulation of translation;GO:0060964//regulation of gene silencing by miRNA;GO:0006355//regulation of transcription, DNA-templated;GO:0045666//positive regulation of neuron differentiation;GO:0010587//miRNA catabolic process;GO:0031123//RNA 3'-end processing",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003729//mRNA binding;GO:0031369//translation initiation factor binding;GO:0035198//miRNA binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
79728,93,0,0,0,22,0,38,0,45,101,0,0,PALB2;partner and localizer of BRCA2,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006281//DNA repair;GO:0036342//post-anal tail morphogenesis;GO:0001756//somitogenesis;GO:0009887//organ morphogenesis;GO:0007498//mesoderm development;GO:0000724//double-strand break repair via homologous recombination;GO:0043066//negative regulation of apoptotic process;GO:0001833//inner cell mass cell proliferation,GO:0003677//DNA binding;GO:0005515//protein binding,K10897//Fanconi anemia pathway
79729,0,1,0,0,0,27,22,0,0,0,10,0,SH3D21;SH3 domain containing 21,GO:0070062//extracellular vesicular exosome,-,-,K12470//Endocytosis;K13738//Bacterial invasion of epithelial cells
79730,0,53,0,33,49,12,0,0,23,0,11,0,"NSUN7;NOP2/Sun domain family, member 7",-,GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0003723//RNA binding,-
79731,0,20,0,1,34,0,19,0,7,0,0,0,"NARS2;asparaginyl-tRNA synthetase 2, mitochondrial (putative)",GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion,GO:0006421//asparaginyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0004816//asparagine-tRNA ligase activity;GO:0005524//ATP binding;GO:0003676//nucleic acid binding,K01893//Aminoacyl-tRNA biosynthesis;Ribosome
79733,104,0,0,0,14,12,0,0,27,0,0,0,E2F8;E2F transcription factor 8,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0032877//positive regulation of DNA endoreduplication;GO:0002040//sprouting angiogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060707//trophoblast giant cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001890//placenta development;GO:0060718//chorionic trophoblast cell differentiation;GO:0032466//negative regulation of cytokinesis;GO:0033301//cell cycle comprising mitosis without cytokinesis;GO:0070365//hepatocyte differentiation;GO:0006351//transcription, DNA-templated",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001047//core promoter binding;GO:0003714//transcription corepressor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
79734,134,0,0,0,0,0,19,0,36,0,0,0,KCTD17;potassium channel tetramerization domain containing 17,-,GO:0051260//protein homooligomerization,GO:0042802//identical protein binding;GO:0005515//protein binding,K08023//TGF-beta signaling pathway
79735,0,107,31,11,17,0,7,0,45,294,37,0,"TBC1D17;TBC1 domain family, member 17",GO:0031410//cytoplasmic vesicle;GO:0005776//autophagic vacuole;GO:0005829//cytosol,"GO:0006914//autophagy;GO:0032851//positive regulation of Rab GTPase activity;GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi;GO:1902017//regulation of cilium assembly",GO:0005097//Rab GTPase activator activity,K13136//RNA transport
79736,0,28,0,0,0,9,0,26,0,0,0,0,"TEFM;transcription elongation factor, mitochondrial",GO:0005759//mitochondrial matrix;GO:0030529//ribonucleoprotein complex;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid,"GO:0006259//DNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006119//oxidative phosphorylation;GO:0006390//transcription from mitochondrial promoter;GO:0006264//mitochondrial DNA replication",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0030337//DNA polymerase processivity factor activity;GO:0008821//crossover junction endodeoxyribonuclease activity,-
79738,0,0,0,0,2,0,13,0,6,0,0,0,BBS10;Bardet-Biedl syndrome 10,GO:0005929//cilium,GO:0035058//nonmotile primary cilium assembly;GO:0007601//visual perception;GO:0050896//response to stimulus;GO:0045494//photoreceptor cell maintenance;GO:0001895//retina homeostasis;GO:0051131//chaperone-mediated protein complex assembly;GO:0043254//regulation of protein complex assembly;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0001103//RNA polymerase II repressing transcription factor binding,-
79739,59,0,0,19,23,17,45,0,13,0,0,0,"TTLL7;tubulin tyrosine ligase-like family, member 7",GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005929//cilium;GO:0030425//dendrite;GO:0043204//perikaryon,GO:0018095//protein polyglutamylation;GO:0007399//nervous system development;GO:0030154//cell differentiation,GO:0016874//ligase activity,"K00273//Glycine, serine and threonine metabolism;Penicillin and cephalosporin biosynthesis;Arginine and proline metabolism;D-Arginine and D-ornithine metabolism;Peroxisome;Metabolic pathways"
79740,0,0,0,0,0,33,0,0,15,0,7,98,"ZBBX;zinc finger, B-box domain containing",GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
79741,0,32,2,51,78,16,16,0,10,57,77,0,CCDC7;coiled-coil domain containing 7,-,-,-,K00907//Focal adhesion;Calcium signaling pathway;Gastric acid secretion;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12592//RNA degradation
79742,11,0,0,0,0,37,30,0,28,1,1,0,CXorf36;chromosome X open reading frame 36,GO:0005576//extracellular region,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
79744,0,0,0,12,37,0,13,0,28,0,0,0,ZNF419;zinc finger protein 419,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79745,0,0,0,0,0,3,47,0,43,0,0,0,"CLIP4;CAP-GLY domain containing linker protein family, member 4",-,-,-,-
79746,82,1,0,5,0,1,0,0,17,0,0,0,ECHDC3;enoyl CoA hydratase domain containing 3,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0003824//catalytic activity,"K07511//Fatty acid metabolism;Lysine degradation;Fatty acid elongation;Propanoate metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;beta-Alanine metabolism;Tryptophan metabolism;Biosynthesis of secondary metabolites;Butanoate metabolism"
79747,66,0,0,0,0,52,11,0,74,116,0,3,ADGB;androglobin,GO:0005737//cytoplasm,GO:0015671//oxygen transport;GO:0006508//proteolysis,GO:0005506//iron ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0020037//heme binding;GO:0019825//oxygen binding,-
79748,0,0,0,0,1,0,21,17,40,234,12,0,"LMAN1L;lectin, mannose-binding, 1 like",GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane,-,GO:0030246//carbohydrate binding,K10081//Protein processing in endoplasmic reticulum
7975,0,27,1,0,26,19,0,0,12,0,18,0,MAFK;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K,GO:0005654//nucleoplasm,"GO:0007399//nervous system development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007596//blood coagulation",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
79750,0,0,0,0,0,0,0,1,22,0,0,0,ZNF385D;zinc finger protein 385D,GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding,-
79751,49,4,0,0,28,4,1,1,0,0,11,0,"SLC25A22;solute carrier family 25 (mitochondrial carrier: glutamate), member 22",GO:0005634//nucleus;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0015813//L-glutamate transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity;GO:0005313//L-glutamate transmembrane transporter activity,-
79752,0,2,0,23,91,0,0,0,2,0,0,0,"ZFAND1;zinc finger, AN1-type domain 1",-,-,GO:0008270//zinc ion binding,-
79753,0,0,0,26,70,0,0,0,0,0,0,0,SNIP1;Smad nuclear interacting protein 1,GO:0005634//nucleus,"GO:0035196//production of miRNAs involved in gene silencing by miRNA;GO:0006355//regulation of transcription, DNA-templated;GO:0007249//I-kappaB kinase/NF-kappaB signaling",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
79754,0,0,0,0,0,0,33,0,71,0,8,0,ASB13;ankyrin repeat and SOCS box containing 13,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
79755,0,0,0,0,28,0,1,51,62,143,14,0,ZNF750;zinc finger protein 750,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0008544//epidermis development;GO:0030154//cell differentiation",GO:0001046//core promoter sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
79758,0,0,0,0,24,18,20,0,11,0,23,0,DHRS12;dehydrogenase/reductase (SDR family) member 12,-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
79759,0,0,0,0,0,0,20,78,0,0,11,0,ZNF668;zinc finger protein 668,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
7976,0,1,8,0,0,51,74,44,100,0,10,0,FZD3;frizzled class receptor 3,GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0016324//apical plasma membrane;GO:0045177//apical part of cell;GO:0032589//neuron projection membrane;GO:0016328//lateral plasma membrane;GO:0030424//axon;GO:0048786//presynaptic active zone,GO:0008406//gonad development;GO:0001764//neuron migration;GO:0030182//neuron differentiation;GO:0060070//canonical Wnt signaling pathway;GO:0001736//establishment of planar polarity;GO:0071679//commissural neuron axon guidance;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0001944//vasculature development;GO:0042472//inner ear morphogenesis;GO:0001942//hair follicle development;GO:0033278//cell proliferation in midbrain;GO:0001843//neural tube closure;GO:0036342//post-anal tail morphogenesis;GO:0021754//facial nucleus development,GO:0017147//Wnt-protein binding;GO:0005515//protein binding;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding;GO:0004930//G-protein coupled receptor activity,K02329//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Wnt signaling pathway;HTLV-I infection
79760,57,37,39,19,92,0,0,64,14,0,75,0,GEMIN7;gem (nuclear organelle) associated protein 7,GO:0005829//cytosol;GO:0005634//nucleus;GO:0097504//Gemini of coiled bodies;GO:0034719//SMN-Sm protein complex;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0016604//nuclear body;GO:0005654//nucleoplasm,"GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0016070//RNA metabolic process",GO:0005515//protein binding,K13135//RNA transport
79762,0,65,1,54,106,0,22,0,0,0,0,0,C1orf115;chromosome 1 open reading frame 115,GO:0016021//integral component of membrane,-,-,-
79763,8,0,0,0,0,11,0,59,0,0,0,0,ISOC2;isochorismatase domain containing 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0031648//protein destabilization;GO:0008152//metabolic process,GO:0003824//catalytic activity;GO:0005515//protein binding,K04432//MAPK signaling pathway;Toxoplasmosis;Amyotrophic lateral sclerosis (ALS);Epstein-Barr virus infection;GnRH signaling pathway;Fc epsilon RI signaling pathway;Toll-like receptor signaling pathway;Influenza A
79767,66,0,0,0,0,0,0,53,0,0,3,0,ELMO3;engulfment and cell motility 3,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0006915//apoptotic process;GO:0006909//phagocytosis,GO:0017124//SH3 domain binding,K12366//Shigellosis;Chemokine signaling pathway;Bacterial invasion of epithelial cells
79768,0,0,0,0,1,0,4,0,6,0,0,0,KATNBL1;katanin p80 subunit B-like 1,GO:0005730//nucleolus,-,-,-
79770,1,0,0,6,12,37,0,0,40,0,36,0,TXNDC15;thioredoxin domain containing 15,GO:0016021//integral component of membrane,GO:0045454//cell redox homeostasis,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79772,0,0,0,0,0,0,0,0,0,140,0,0,"MCTP1;multiple C2 domains, transmembrane 1",GO:0016021//integral component of membrane,GO:0019722//calcium-mediated signaling,GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,K15290//Synaptic vesicle cycle
79774,0,0,0,0,13,0,0,0,0,0,0,0,GRTP1;growth hormone regulated TBC protein 1,-,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
79776,322,1,0,0,13,0,140,0,104,1,11,1,ZFHX4;zinc finger homeobox 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding,-
79777,0,0,0,0,0,0,12,105,8,0,0,0,ACBD4;acyl-CoA binding domain containing 4,-,-,GO:0008289//lipid binding;GO:0000062//fatty-acyl-CoA binding,K08762//PPAR signaling pathway;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
79778,0,0,0,0,0,5,0,0,39,237,7,0,MICALL2;MICAL-like 2,GO:0043005//neuron projection;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0032432//actin filament bundle;GO:0005829//cytosol;GO:0005923//tight junction;GO:0055037//recycling endosome;GO:0001725//stress fiber,GO:0034446//substrate adhesion-dependent cell spreading;GO:0070830//tight junction assembly;GO:0031175//neuron projection development;GO:0031532//actin cytoskeleton reorganization;GO:0030041//actin filament polymerization;GO:0032456//endocytic recycling,GO:0017137//Rab GTPase binding;GO:0031005//filamin binding;GO:0051015//actin filament binding;GO:0008270//zinc ion binding;GO:0042805//actinin binding,K05699//Leukocyte transendothelial migration;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Adherens junction;Focal adhesion;Amoebiasis;Systemic lupus erythematosus;Regulation of actin cytoskeleton
79780,0,0,0,16,8,21,0,0,42,0,0,0,CCDC82;coiled-coil domain containing 82,-,-,-,-
79781,0,0,0,0,0,0,0,0,14,1,12,0,IQCA1;IQ motif containing with AAA domain 1,-,-,GO:0005524//ATP binding,K00665//Fatty acid biosynthesis;Metabolic pathways;Insulin signaling pathway;K12196//Endocytosis
79782,0,0,0,0,0,0,0,0,0,0,5,0,LRRC31;leucine rich repeat containing 31,-,-,-,K12807//NOD-like receptor signaling pathway;Legionellosis;K12800//Pertussis;NOD-like receptor signaling pathway;Influenza A;K12805//NOD-like receptor signaling pathway;Legionellosis;Salmonella infection;K14319//RNA transport
79783,48,0,0,0,7,0,6,0,0,0,1,1,SUGCT;succinyl-CoA:glutarate-CoA transferase,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0047369//succinate-hydroxymethylglutarate CoA-transferase activity,K01796//Primary bile acid biosynthesis;Metabolic pathways;Peroxisome
79784,25,0,0,0,14,35,0,25,57,105,14,2,"MYH14;myosin, heavy chain 14, non-muscle",GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0097513//myosin II filament;GO:0042641//actomyosin;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0016460//myosin II complex;GO:0001725//stress fiber;GO:0030424//axon,GO:0071625//vocalization behavior;GO:0006200//ATP catabolic process;GO:0014732//skeletal muscle atrophy;GO:0031032//actomyosin structure organization;GO:0030048//actin filament-based movement;GO:0070584//mitochondrion morphogenesis;GO:0007605//sensory perception of sound;GO:0007411//axon guidance;GO:0019228//neuronal action potential;GO:0003009//skeletal muscle contraction;GO:0008360//regulation of cell shape;GO:0007519//skeletal muscle tissue development,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0030898//actin-dependent ATPase activity;GO:0051015//actin filament binding;GO:0000146//microfilament motor activity,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
79786,0,20,0,4,1,0,24,10,16,0,0,0,KLHL36;kelch-like family member 36,-,GO:0016567//protein ubiquitination,-,-
79788,0,0,1,0,0,1,47,0,4,65,0,0,ZNF665;zinc finger protein 665,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
79789,0,21,1,87,164,0,4,54,22,0,0,0,"CLMN;calmin (calponin-like, transmembrane)",GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0008285//negative regulation of cell proliferation;GO:0031175//neuron projection development,GO:0003779//actin binding,K06115//Tight junction
7979,0,0,0,1,0,0,0,0,0,0,0,0,SHFM1;split hand/foot malformation (ectrodactyly) type 1,GO:0000502//proteasome complex;GO:0032039//integrator complex,GO:0000724//double-strand break repair via homologous recombination,GO:0005515//protein binding,K10881//Proteasome;Epstein-Barr virus infection;Homologous recombination
79791,0,1,0,0,25,23,9,63,15,84,9,0,FBXO31;F-box protein 31,GO:0019005//SCF ubiquitin ligase complex,GO:0008054//cyclin catabolic process;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0016567//protein ubiquitination;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0006974//cellular response to DNA damage stimulus,GO:0030332//cyclin binding,-
79792,66,0,0,0,1,0,0,1,22,0,3,123,GSDMD;gasdermin D,-,GO:0031668//cellular response to extracellular stimulus,-,-
79794,0,0,0,0,5,0,16,0,44,0,18,320,C12orf49;chromosome 12 open reading frame 49,GO:0005576//extracellular region,-,-,-
79796,33,0,0,0,1,8,0,0,31,0,19,0,"ALG9;ALG9, alpha-1,2-mannosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0097502//mannosylation;GO:0043687//post-translational protein modification,"GO:0052926//dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity;GO:0052918//dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity",K03846//N-Glycan biosynthesis;Various types of N-glycan biosynthesis;Metabolic pathways
79797,0,0,0,0,0,32,0,0,4,0,0,0,ZNF408;zinc finger protein 408,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
79798,0,40,150,103,160,0,1,127,33,0,30,0,ARMC5;armadillo repeat containing 5,-,-,-,-
79799,0,0,0,0,0,0,32,0,21,0,0,14,"UGT2A3;UDP glucuronosyltransferase 2 family, polypeptide A3",GO:0016021//integral component of membrane,GO:0052695//cellular glucuronidation,GO:0015020//glucuronosyltransferase activity,K00699//Starch and sucrose metabolism;Steroid hormone biosynthesis;Drug metabolism - other enzymes;Porphyrin and chlorophyll metabolism;Ascorbate and aldarate metabolism;Other types of O-glycan biosynthesis;Metabolism of xenobiotics by cytochrome P450;Bile secretion;Retinol metabolism;Metabolic pathways;Drug metabolism - cytochrome P450;Pentose and glucuronate interconversions
7980,0,0,0,0,0,2,50,0,0,0,0,0,TFPI2;tissue factor pathway inhibitor 2,GO:0005578//proteinaceous extracellular matrix;GO:0005634//nucleus,GO:0010951//negative regulation of endopeptidase activity;GO:0007596//blood coagulation,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005201//extracellular matrix structural constituent,K03909//Complement and coagulation cascades
79800,0,0,0,7,35,32,60,0,36,0,0,0,CARF;calcium responsive transcription factor,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0035865//cellular response to potassium ion;GO:0071277//cellular response to calcium ion;GO:0006351//transcription, DNA-templated;GO:0061400//positive regulation of transcription from RNA polymerase II promoter in response to calcium ion",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
79801,0,0,0,0,1,17,0,0,11,0,0,0,SHCBP1;SHC SH2-domain binding protein 1,-,GO:2000177//regulation of neural precursor cell proliferation;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0042169//SH2 domain binding,K01081//Nicotinate and nicotinamide metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
79802,0,0,0,0,0,0,3,0,11,0,8,0,HHIPL2;HHIP-like 2,GO:0005576//extracellular region,GO:0055114//oxidation-reduction process;GO:0005975//carbohydrate metabolic process,"GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0048038//quinone binding",K06231//Hedgehog signaling pathway;Pathways in cancer;Basal cell carcinoma
79803,0,0,0,0,0,0,0,0,13,80,18,0,HPS6;Hermansky-Pudlak syndrome 6,GO:0031084//BLOC-2 complex;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0031901//early endosome membrane,GO:0006996//organelle organization;GO:0030318//melanocyte differentiation;GO:0072657//protein localization to membrane;GO:0007596//blood coagulation,GO:0017137//Rab GTPase binding;GO:0030742//GTP-dependent protein binding,-
79807,0,1,1,0,26,34,111,21,20,107,0,0,"GSTCD;glutathione S-transferase, C-terminal domain containing",GO:0070062//extracellular vesicular exosome,-,GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79809,0,0,0,7,59,0,20,0,38,0,0,0,TTC21B;tetratricopeptide repeat domain 21B,GO:0005929//cilium;GO:0030991//intraciliary transport particle A;GO:0000790//nuclear chromatin;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0061512//protein localization to cilium;GO:0035721//intraciliary retrograde transport;GO:0008589//regulation of smoothened signaling pathway;GO:0035735//intraciliary transport involved in cilium morphogenesis;GO:0007224//smoothened signaling pathway;GO:0021591//ventricular system development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0021798//forebrain dorsal/ventral pattern formation,-,K09553//Prion diseases;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79810,0,0,0,0,0,0,0,0,45,0,0,0,PTCD2;pentatricopeptide repeat domain 2,GO:0005739//mitochondrion,GO:0048747//muscle fiber development;GO:0050684//regulation of mRNA processing;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0001822//kidney development;GO:0007005//mitochondrion organization;GO:0006397//mRNA processing;GO:0001889//liver development,GO:0044822//poly(A) RNA binding,-
79811,37,0,0,8,43,0,0,59,6,0,0,0,"SLTM;SAFB-like, transcription modulator",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006355//regulation of transcription, DNA-templated",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,-
79812,0,0,0,0,0,0,9,0,33,138,0,0,MMRN2;multimerin 2,GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome,GO:0001525//angiogenesis;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0030948//negative regulation of vascular endothelial growth factor receptor signaling pathway,GO:0005515//protein binding,-
79813,135,0,11,0,12,27,1,34,39,0,5,625,EHMT1;euchromatic histone-lysine N-methyltransferase 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005694//chromosome,"GO:0051567//histone H3-K9 methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0018027//peptidyl-lysine dimethylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0070734//histone H3-K27 methylation;GO:0009790//embryo development;GO:0016571//histone methylation;GO:0018026//peptidyl-lysine monomethylation;GO:0006306//DNA methylation;GO:0016568//chromatin modification",GO:0018024//histone-lysine N-methyltransferase activity;GO:0046976//histone methyltransferase activity (H3-K27 specific);GO:0070742//C2H2 zinc finger domain binding;GO:0002039//p53 binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0008168//methyltransferase activity;GO:0008270//zinc ion binding;GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0005515//protein binding,K11420//Lysine degradation
79814,0,0,1,0,0,22,18,0,0,0,0,0,AGMAT;agmatine ureohydrolase (agmatinase),GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0097055//agmatine biosynthetic process;GO:0008295//spermidine biosynthetic process;GO:0033388//putrescine biosynthetic process from arginine;GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0046872//metal ion binding;GO:0008783//agmatinase activity,K01480//Arginine and proline metabolism;Metabolic pathways
79815,0,0,0,8,46,0,21,0,35,0,10,0,NIPAL2;NIPA-like domain containing 2,GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
79816,0,0,0,0,0,10,18,0,24,0,0,0,TLE6;transducin-like enhancer of split 6,GO:0005634//nucleus;GO:0005938//cell cortex;GO:0043234//protein complex,"GO:0006355//regulation of transcription, DNA-templated",-,K04497//Notch signaling pathway;Wnt signaling pathway
79817,73,0,0,0,0,0,3,120,50,143,9,0,MOB3B;MOB kinase activator 3B,-,-,GO:0046872//metal ion binding;GO:0005515//protein binding,K04372//MAPK signaling pathway;Insulin signaling pathway;K06685//Cell cycle - yeast
79818,0,0,0,15,0,0,17,0,0,6,0,0,ZNF552;zinc finger protein 552,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79819,0,0,0,0,0,32,27,0,70,0,0,381,WDR78;WD repeat domain 78,-,GO:0002244//hematopoietic progenitor cell differentiation,-,K10409//Huntington's disease
7982,0,0,0,0,20,9,55,0,44,0,0,0,ST7;suppression of tumorigenicity 7,GO:0016021//integral component of membrane,-,-,-
79820,0,1,0,0,0,34,0,0,22,0,17,0,CATSPERB;catsper channel auxiliary subunit beta,GO:0005886//plasma membrane;GO:0036128//CatSper complex;GO:0005929//cilium,GO:0030154//cell differentiation;GO:0032504//multicellular organism reproduction;GO:0007283//spermatogenesis;GO:0035036//sperm-egg recognition;GO:0007338//single fertilization;GO:0007275//multicellular organismal development,-,-
79822,0,0,1,13,6,9,42,0,16,0,0,0,ARHGAP28;Rho GTPase activating protein 28,GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005829//cytosol;GO:0005634//nucleus,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K08878//Pathways in cancer;Chronic myeloid leukemia
79823,0,0,0,0,14,0,0,0,0,0,0,0,CAMKMT;calmodulin-lysine N-methyltransferase,GO:0005634//nucleus;GO:0005794//Golgi apparatus,GO:0018022//peptidyl-lysine methylation,GO:0018025//calmodulin-lysine N-methyltransferase activity,-
79825,0,0,0,0,27,12,1,0,7,0,0,0,EFCC1;EF-hand and coiled-coil domain containing 1,-,-,GO:0005509//calcium ion binding,-
79827,0,0,0,0,16,17,0,0,0,0,35,0,CLMP;CXADR-like membrane protein,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005881//cytoplasmic microtubule,GO:0048565//digestive tract development,-,-
79828,0,30,69,12,57,0,11,0,20,0,56,0,METTL8;methyltransferase like 8,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032259//methylation,GO:0008168//methyltransferase activity,K00599//Lipopolysaccharide biosynthesis;Microbial metabolism in diverse environments;Tyrosine metabolism;Histidine metabolism;Metabolic pathways;Polycyclic aromatic hydrocarbon degradation
79830,25,0,0,9,17,0,0,11,8,0,17,0,"ZMYM1;zinc finger, MYM-type 1",GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding;GO:0046983//protein dimerization activity,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
79831,0,49,45,46,41,0,45,0,16,0,47,485,KDM8;lysine (K)-specific demethylase 8,GO:0005634//nucleus,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0055114//oxidation-reduction process;GO:0070544//histone H3-K36 demethylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0051864//histone demethylase activity (H3-K36 specific);GO:0046872//metal ion binding,K01047//Metabolic pathways;Vascular smooth muscle contraction;Glutamatergic synapse;Linoleic acid metabolism;MAPK signaling pathway;alpha-Linolenic acid metabolism;Serotonergic synapse;Pancreatic secretion;GnRH signaling pathway;Ether lipid metabolism;VEGF signaling pathway;Glycerophospholipid metabolism;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway
79832,0,0,0,21,54,22,30,0,48,0,0,0,QSER1;glutamine and serine rich 1,-,-,-,-
79833,0,0,0,0,0,0,0,0,2,0,0,0,GEMIN6;gem (nuclear organelle) associated protein 6,GO:0097504//Gemini of coiled bodies;GO:0034719//SMN-Sm protein complex;GO:0005829//cytosol;GO:0032797//SMN complex;GO:0005737//cytoplasm;GO:0016604//nuclear body;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0016070//RNA metabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000245//spliceosomal complex assembly",GO:0005515//protein binding,K13134//RNA transport
79834,16,0,0,0,15,22,33,0,75,195,0,0,PEAK1;pseudopodium-enriched atypical kinase 1,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion,GO:0046777//protein autophosphorylation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0016477//cell migration,GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005515//protein binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption
79836,0,0,0,0,0,7,45,0,15,0,0,0,LONRF3;LON peptidase N-terminal domain and ring finger 3,-,GO:0006200//ATP catabolic process;GO:0006508//proteolysis,GO:0004176//ATP-dependent peptidase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,K09553//Prion diseases
79837,0,27,1,1,54,0,0,0,17,37,6,0,"PIP4K2C;phosphatidylinositol-5-phosphate 4-kinase, type II, gamma",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0046854//phosphatidylinositol phosphorylation,GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0005524//ATP binding;GO:0042802//identical protein binding,K00920//Metabolic pathways;Regulation of actin cytoskeleton;Endocytosis;Phosphatidylinositol signaling system;Inositol phosphate metabolism
79838,3,17,0,16,88,0,13,0,29,0,17,0,TMC5;transmembrane channel-like 5,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,GO:0006811//ion transport,-,K01539//Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K06237//Focal adhesion;Small cell lung cancer;Protein digestion and absorption;Amoebiasis;Pathways in cancer;ECM-receptor interaction
79839,0,0,0,0,0,13,0,0,0,0,0,0,CCDC102B;coiled-coil domain containing 102B,-,-,-,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
7984,0,0,8,15,4,13,18,8,17,1,26,0,ARHGEF5;Rho guanine nucleotide exchange factor (GEF) 5,-,GO:0032321//positive regulation of Rho GTPase activity;GO:0032319//regulation of Rho GTPase activity;GO:0030036//actin cytoskeleton organization;GO:0071803//positive regulation of podosome assembly;GO:0035556//intracellular signal transduction;GO:0002408//myeloid dendritic cell chemotaxis,GO:0005525//GTP binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K07525//Axon guidance
79840,0,0,0,8,11,17,0,0,26,0,0,0,NHEJ1;nonhomologous end-joining factor 1,GO:0070419//nonhomologous end joining complex;GO:0005634//nucleus,GO:0030217//T cell differentiation;GO:0007417//central nervous system development;GO:0006310//DNA recombination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0010212//response to ionizing radiation;GO:0051351//positive regulation of ligase activity;GO:0030183//B cell differentiation,GO:0003677//DNA binding;GO:0005515//protein binding,K10980//Non-homologous end-joining
79841,0,0,11,0,7,0,0,33,44,0,0,0,AGBL2;ATP/GTP binding protein-like 2,GO:0005829//cytosol,GO:0006508//proteolysis,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,K14611//Vitamin digestion and absorption
79842,0,17,0,0,8,0,0,0,6,152,0,0,ZBTB3;zinc finger and BTB domain containing 3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79843,0,0,0,0,0,0,47,0,14,0,0,0,FAM124B;family with sequence similarity 124B,-,-,GO:0005515//protein binding,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
79844,0,0,0,0,0,19,0,0,66,0,0,0,"ZDHHC11;zinc finger, DHHC-type containing 11",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0008270//zinc ion binding,K14000//Protein processing in endoplasmic reticulum
79845,0,0,0,0,0,8,0,0,35,144,0,0,RNF122;ring finger protein 122,GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,GO:0008270//zinc ion binding,-
79846,108,28,0,35,133,26,8,2,95,0,1,0,C7orf63;chromosome 7 open reading frame 63,-,-,-,-
79847,81,0,0,0,7,0,12,0,15,204,10,0,TMEM180;transmembrane protein 180,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
79848,0,0,1,16,53,0,0,0,16,0,21,0,CSPP1;centrosome and spindle pole associated protein 1,GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005874//microtubule;GO:0000922//spindle pole;GO:0005819//spindle,GO:0032467//positive regulation of cytokinesis;GO:0051781//positive regulation of cell division,-,-
79849,0,0,0,0,0,0,0,0,11,0,0,0,PDZD3;PDZ domain containing 3,GO:0005903//brush border;GO:0045177//apical part of cell;GO:0035003//subapical complex;GO:0005829//cytosol,GO:0030827//negative regulation of cGMP biosynthetic process;GO:0006811//ion transport;GO:0019934//cGMP-mediated signaling;GO:0031283//negative regulation of guanylate cyclase activity;GO:0007168//receptor guanylyl cyclase signaling pathway;GO:0009636//response to toxic substance;GO:0006833//water transport,GO:0008022//protein C-terminus binding;GO:0030251//guanylate cyclase inhibitor activity;GO:0008200//ion channel inhibitor activity;GO:0005515//protein binding,K13358//Aldosterone-regulated sodium reabsorption
79850,0,0,33,26,50,0,0,115,37,5,23,0,"FAM57A;family with sequence similarity 57, member A",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
79852,0,0,0,0,0,0,0,0,21,0,0,244,EPHX3;epoxide hydrolase 3,GO:0005576//extracellular region,GO:0008152//metabolic process,GO:0016787//hydrolase activity,K08059//Antigen processing and presentation;K08726//Peroxisome;Arachidonic acid metabolism;Metabolic pathways
79853,0,0,0,0,0,11,7,0,0,125,10,0,TM4SF20;transmembrane 4 L six family member 20,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
79854,0,1,41,20,25,0,0,14,0,0,19,0,LINC00115;long intergenic non-protein coding RNA 115,-,-,-,-
79856,180,826,232,579,752,14,61,92,133,0,804,0,SNX22;sorting nexin 22,GO:0030659//cytoplasmic vesicle membrane,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding,-
79857,0,0,0,0,35,0,0,0,5,0,0,0,FLJ13224;uncharacterized LOC79857,-,-,-,-
79858,0,0,0,11,0,16,0,0,27,0,0,0,NEK11;NIMA-related kinase 11,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0031573//intra-S DNA damage checkpoint;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0031572//G2 DNA damage checkpoint,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
79861,0,0,0,0,0,0,0,0,14,0,0,0,"TUBAL3;tubulin, alpha-like 3",GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007017//microtubule-based process;GO:0006184//GTP catabolic process;GO:0051258//protein polymerization,GO:0005200//structural constituent of cytoskeleton;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07374//Pathogenic Escherichia coli infection;Phagosome;Gap junction
79862,0,0,0,0,0,0,0,40,22,0,0,0,ZNF669;zinc finger protein 669,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79863,0,1,0,0,0,9,25,0,35,36,1,0,RBFA;ribosome binding factor A (putative),GO:0005739//mitochondrion,GO:0006364//rRNA processing,-,-
79864,0,0,0,0,12,23,0,0,30,0,0,0,C11orf63;chromosome 11 open reading frame 63,-,GO:0007420//brain development;GO:0035082//axoneme assembly;GO:0033326//cerebrospinal fluid secretion,-,K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
79865,50,0,0,0,15,20,61,84,30,0,6,0,TREML2;triggering receptor expressed on myeloid cells-like 2,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0042110//T cell activation,GO:0005515//protein binding;GO:0004872//receptor activity,-
79866,0,0,0,30,52,0,0,0,30,0,0,0,"BORA;bora, aurora kinase A activator",GO:0005829//cytosol,GO:0060236//regulation of mitotic spindle organization;GO:0032880//regulation of protein localization;GO:0007088//regulation of mitosis;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0019901//protein kinase binding;GO:0005515//protein binding,-
79867,0,0,0,1,10,14,25,0,7,0,10,0,TCTN2;tectonic family member 2,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0036038//TCTN-B9D complex;GO:0005856//cytoskeleton,GO:0007224//smoothened signaling pathway;GO:0060271//cilium morphogenesis;GO:0042384//cilium assembly,-,K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
79868,125,75,0,15,15,0,59,0,62,48,22,0,"ALG13;ALG13, UDP-N-acetylglucosaminyltransferase subunit",GO:0005789//endoplasmic reticulum membrane,GO:0006508//proteolysis;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0030259//lipid glycosylation,GO:0030246//carbohydrate binding;GO:0008234//cysteine-type peptidase activity;GO:0044822//poly(A) RNA binding;GO:0004577//N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity,K07432//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
79869,75,0,1,12,25,17,0,0,44,0,0,0,"CPSF7;cleavage and polyadenylation specific factor 7, 59kDa",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005849//mRNA cleavage factor complex;GO:0016020//membrane,"GO:0000398//mRNA splicing, via spliceosome;GO:0051262//protein tetramerization;GO:0006366//transcription from RNA polymerase II promoter;GO:0031124//mRNA 3'-end processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K14398//mRNA surveillance pathway
79870,0,0,0,0,0,0,0,49,7,158,8,0,"BAALC;brain and acute leukemia, cytoplasmic",GO:0016020//membrane;GO:0005737//cytoplasm,-,-,-
79871,0,36,0,3,12,0,0,0,26,0,0,0,RPAP2;RNA polymerase II associated protein 2,"GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005634//nucleus",GO:0070940//dephosphorylation of RNA polymerase II C-terminal domain;GO:0009301//snRNA transcription,GO:0046872//metal ion binding;GO:0008420//CTD phosphatase activity,-
79872,0,33,2,26,34,1,19,0,37,0,0,0,"CBLL1;Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase",GO:0000151//ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0016337//single organismal cell-cell adhesion;GO:0030335//positive regulation of cell migration;GO:0045807//positive regulation of endocytosis;GO:0007162//negative regulation of cell adhesion,GO:0042802//identical protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
79873,0,0,0,1,0,0,0,0,18,0,0,0,NUDT18;nudix (nucleoside diphosphate linked moiety X)-type motif 18,GO:0005829//cytosol,GO:0046712//GDP catabolic process;GO:0046067//dGDP catabolic process;GO:0034656//nucleobase-containing small molecule catabolic process;GO:0046057//dADP catabolic process;GO:0044281//small molecule metabolic process,GO:0044715//8-oxo-dGDP phosphatase activity;GO:0005515//protein binding;GO:0044717//8-hydroxy-dADP phosphatase activity;GO:0044716//8-oxo-GDP phosphatase activity;GO:0000287//magnesium ion binding,-
79874,80,0,2,0,7,0,0,1,10,0,1,4,"RABEP2;rabaptin, RAB GTPase binding effector protein 2",GO:0005769//early endosome;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006897//endocytosis;GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport,GO:0005096//GTPase activator activity;GO:0008083//growth factor activity,K12480//Endocytosis
79875,8,12,0,6,13,51,94,0,51,0,1,0,"THSD4;thrombospondin, type I, domain containing 4",GO:0070062//extracellular vesicular exosome;GO:0001527//microfibril,GO:0006508//proteolysis;GO:0048251//elastic fiber assembly,GO:0004222//metalloendopeptidase activity,-
79876,0,46,0,29,83,0,15,51,32,0,0,0,UBA5;ubiquitin-like modifier activating enzyme 5,GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071569//protein ufmylation;GO:0034976//response to endoplasmic reticulum stress,GO:0071566//UFM1 activating enzyme activity;GO:0005524//ATP binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
79877,0,0,0,1,26,5,0,59,21,0,0,0,DCAKD;dephospho-CoA kinase domain containing,GO:0005739//mitochondrion;GO:0016020//membrane,GO:0016310//phosphorylation;GO:0015937//coenzyme A biosynthetic process,GO:0004140//dephospho-CoA kinase activity;GO:0005524//ATP binding,K02318//Pantothenate and CoA biosynthesis;Metabolic pathways;K00859//Metabolic pathways;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Purine metabolism
79879,0,0,0,0,0,22,16,0,15,0,5,0,CCDC134;coiled-coil domain containing 134,GO:0016020//membrane;GO:0005576//extracellular region,-,-,-
7988,0,2,0,0,7,0,0,0,11,0,38,0,ZNF212;zinc finger protein 212,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
79882,0,23,1,152,275,47,0,0,61,115,27,0,ZC3H14;zinc finger CCCH-type containing 14,GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
79883,0,0,0,0,8,2,27,0,30,0,0,0,PODNL1;podocan-like 1,GO:0005578//proteinaceous extracellular matrix,-,-,K08764//PPAR signaling pathway;Metabolic pathways;Primary bile acid biosynthesis;Peroxisome
79884,0,6,0,97,42,0,94,0,111,0,1,0,MAP9;microtubule-associated protein 9,GO:0000235//astral microtubule;GO:1990023//mitotic spindle midzone,GO:0090307//spindle assembly involved in mitosis;GO:0007088//regulation of mitosis;GO:0000910//cytokinesis,-,-
79885,42,1,0,0,1,17,0,0,27,171,1,0,HDAC11;histone deacetylase 11,GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0016568//chromatin modification;GO:0070932//histone H3 deacetylation;GO:0006355//regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0006351//transcription, DNA-templated;GO:0070933//histone H4 deacetylation;GO:0014003//oligodendrocyte development",GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding;GO:0004407//histone deacetylase activity;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific),K11418//Alcoholism
79886,0,0,0,0,3,0,0,0,26,0,6,0,CAAP1;caspase activity and apoptosis inhibitor 1,-,GO:0006915//apoptotic process,-,K14018//Protein processing in endoplasmic reticulum
79887,43,59,0,17,48,0,39,0,36,0,53,0,PLBD1;phospholipase B domain containing 1,GO:0005829//cytosol;GO:0005764//lysosome,GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling,GO:0016787//hydrolase activity,-
79888,0,0,0,0,3,0,0,0,32,127,4,0,LPCAT1;lysophosphatidylcholine acyltransferase 1,GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005811//lipid particle;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0008654//phospholipid biosynthetic process;GO:2001246//negative regulation of phosphatidylcholine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0045732//positive regulation of protein catabolic process;GO:0060041//retina development in camera-type eye;GO:0046474//glycerophospholipid biosynthetic process;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0043129//surfactant homeostasis;GO:0006654//phosphatidic acid biosynthetic process;GO:0036151//phosphatidylcholine acyl-chain remodeling,GO:0047159//1-alkenylglycerophosphocholine O-acyltransferase activity;GO:0047191//1-alkylglycerophosphocholine O-acyltransferase activity;GO:0047184//1-acylglycerophosphocholine O-acyltransferase activity;GO:0047192//1-alkylglycerophosphocholine O-acetyltransferase activity;GO:0005509//calcium ion binding,K13510//Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
79890,0,0,0,9,17,0,0,145,14,283,38,0,RIN3;Ras and Rab interactor 3,GO:0005769//early endosome;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031410//cytoplasmic vesicle,GO:0032851//positive regulation of Rab GTPase activity;GO:0007165//signal transduction;GO:0006897//endocytosis,GO:0005096//GTPase activator activity;GO:0017137//Rab GTPase binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
79891,0,0,0,1,7,0,21,113,0,0,0,0,ZNF671;zinc finger protein 671,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
79892,0,16,0,8,29,31,16,0,34,0,0,319,MCMBP;minichromosome maintenance complex binding protein,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0042555//MCM complex;GO:0005634//nucleus,GO:0006261//DNA-dependent DNA replication;GO:0007067//mitotic nuclear division;GO:0007062//sister chromatid cohesion,GO:0005515//protein binding;GO:0003682//chromatin binding,-
79893,0,0,0,4,57,0,0,2,70,100,0,0,GGNBP2;gametogenetin binding protein 2,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,-
79894,0,0,0,1,0,0,0,0,11,0,0,171,ZNF672;zinc finger protein 672,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79895,60,30,1,52,87,40,35,0,27,0,7,130,"ATP8B4;ATPase, class I, type 8B, member 4",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process;GO:0045332//phospholipid translocation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004012//phospholipid-translocating ATPase activity;GO:0019829//cation-transporting ATPase activity,K01530//Purine metabolism
79896,0,0,0,0,0,35,0,0,10,22,0,0,THNSL1;threonine synthase-like 1 (S. cerevisiae),GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
79898,0,2,31,1,39,0,1,0,22,0,20,0,ZNF613;zinc finger protein 613,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79899,37,0,0,0,0,1,14,0,21,0,2,0,PRR5L;proline rich 5 like,GO:0031932//TORC2 complex;GO:0005739//mitochondrion,GO:0001933//negative regulation of protein phosphorylation;GO:0010762//regulation of fibroblast migration;GO:0009968//negative regulation of signal transduction;GO:0038203//TORC2 signaling;GO:0001934//positive regulation of protein phosphorylation;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling,GO:0031625//ubiquitin protein ligase binding,-
799,0,0,0,0,0,22,0,0,0,0,0,0,CALCR;calcitonin receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007190//activation of adenylate cyclase activity;GO:0072659//protein localization to plasma membrane;GO:0007186//G-protein coupled receptor signaling pathway;GO:0045762//positive regulation of adenylate cyclase activity;GO:0015031//protein transport;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007202//activation of phospholipase C activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0031623//receptor internalization;GO:0051384//response to glucocorticoid,GO:0032841//calcitonin binding;GO:0008565//protein transporter activity;GO:0004948//calcitonin receptor activity;GO:0004872//receptor activity;GO:0005515//protein binding,K04576//Neuroactive ligand-receptor interaction;Osteoclast differentiation
79901,0,0,0,0,0,15,22,4,3,0,0,0,CYBRD1;cytochrome b reductase 1,GO:0016021//integral component of membrane;GO:0031526//brush border membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0010039//response to iron ion;GO:0006879//cellular iron ion homeostasis;GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0000293//ferric-chelate reductase activity,K08370//Mineral absorption
79902,0,0,1,16,4,0,0,51,34,0,9,270,NUP85;nucleoporin 85kDa,GO:0005819//spindle;GO:0031965//nuclear membrane;GO:0000776//kinetochore;GO:0016020//membrane;GO:0000777//condensed chromosome kinetochore;GO:0031080//nuclear pore outer ring;GO:0005635//nuclear envelope;GO:0005829//cytosol,GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0030032//lamellipodium assembly;GO:0015031//protein transport;GO:0048246//macrophage chemotaxis;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport;GO:0051028//mRNA transport,GO:0005515//protein binding,K14304//RNA transport
79903,0,0,22,0,1,0,0,0,6,0,5,0,"NAA60;N(alpha)-acetyltransferase 60, NatF catalytic subunit",GO:0000139//Golgi membrane,GO:0007059//chromosome segregation;GO:0043967//histone H4 acetylation;GO:0008283//cell proliferation;GO:0006334//nucleosome assembly;GO:0017196//N-terminal peptidyl-methionine acetylation,GO:0010485//H4 histone acetyltransferase activity;GO:0004596//peptide alpha-N-acetyltransferase activity,K14021//Protein processing in endoplasmic reticulum
79905,0,0,0,0,1,5,0,0,0,0,20,0,TMC7;transmembrane channel-like 7,GO:0016021//integral component of membrane,GO:0006811//ion transport,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
79908,0,0,0,0,0,0,45,39,12,0,0,0,BTNL8;butyrophilin-like 8,GO:0016021//integral component of membrane,GO:0002376//immune system process,GO:0005515//protein binding,-
7991,3,0,0,4,40,0,70,0,67,0,0,0,TUSC3;tumor suppressor candidate 3,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0008250//oligosaccharyltransferase complex,GO:0045454//cell redox homeostasis;GO:0006487//protein N-linked glycosylation;GO:0015693//magnesium ion transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0050890//cognition;GO:0043687//post-translational protein modification,GO:0004579//dolichyl-diphosphooligosaccharide-protein glycotransferase activity;GO:0015095//magnesium ion transmembrane transporter activity,K12669//Protein processing in endoplasmic reticulum;N-Glycan biosynthesis;Metabolic pathways;Various types of N-glycan biosynthesis
79912,0,178,55,125,232,9,0,0,24,0,129,0,PYROXD1;pyridine nucleotide-disulphide oxidoreductase domain 1,-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,-
79913,0,0,0,0,0,0,0,0,52,0,8,0,ACTR5;ARP5 actin-related protein 5 homolog (yeast),GO:0005737//cytoplasm;GO:0031011//Ino80 complex;GO:0005634//nucleus,"GO:0006302//double-strand break repair;GO:0006310//DNA recombination;GO:0006355//regulation of transcription, DNA-templated;GO:0070914//UV-damage excision repair;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
79915,109,0,0,0,0,11,0,14,58,0,0,0,"ATAD5;ATPase family, AAA domain containing 5",GO:0005634//nucleus,GO:0006974//cellular response to DNA damage stimulus,GO:0005524//ATP binding,K10754//Mismatch repair;DNA replication;Nucleotide excision repair
79917,98,0,0,0,0,13,0,0,31,0,10,1,"MAGIX;MAGI family member, X-linked",-,-,-,K06112//Tight junction;K05631//Tight junction;K05629//Tight junction
79918,0,107,99,223,290,26,1,179,41,0,249,0,SETD6;SET domain containing 6,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050727//regulation of inflammatory response;GO:0018026//peptidyl-lysine monomethylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0005515//protein binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0051059//NF-kappaB binding,-
79919,0,0,0,0,0,20,1,0,0,0,0,0,C2orf54;chromosome 2 open reading frame 54,-,-,-,-
79921,0,0,0,12,1,0,0,0,0,0,0,0,TCEAL4;transcription elongation factor A (SII)-like 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
79922,0,0,0,0,1,13,0,46,8,0,0,0,MRM1;mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae),GO:0005739//mitochondrion,GO:0006396//RNA processing;GO:0001510//RNA methylation,GO:0008173//RNA methyltransferase activity;GO:0044822//poly(A) RNA binding,-
79925,0,25,0,1,1,32,54,0,120,0,8,0,SPEF2;sperm flagellar 2,GO:0002177//manchette;GO:0005794//Golgi apparatus;GO:0097225//sperm midpiece,GO:0002520//immune system development;GO:0007283//spermatogenesis;GO:0048702//embryonic neurocranium morphogenesis;GO:0009566//fertilization;GO:0048854//brain morphogenesis;GO:0035082//axoneme assembly;GO:0060541//respiratory system development;GO:0010259//multicellular organismal aging,GO:0046983//protein dimerization activity,-
79927,0,0,0,0,0,15,0,0,7,0,0,0,"FAM110D;family with sequence similarity 110, member D",-,-,-,-
79929,131,0,0,0,0,23,8,0,23,0,0,0,MAP6D1;MAP6 domain containing 1,GO:0005801//cis-Golgi network;GO:0005874//microtubule;GO:0005798//Golgi-associated vesicle,GO:0048813//dendrite morphogenesis;GO:0018009//N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0007026//negative regulation of microtubule depolymerization;GO:0032418//lysosome localization;GO:0000226//microtubule cytoskeleton organization,GO:0005516//calmodulin binding;GO:0008017//microtubule binding,-
7993,0,0,0,0,7,7,0,1,21,0,0,828,UBXN8;UBX domain protein 8,GO:0030176//integral component of endoplasmic reticulum membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0007338//single fertilization,GO:0005515//protein binding,-
79930,73,0,0,0,0,16,36,0,8,0,22,0,DOK3;docking protein 3,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007265//Ras protein signal transduction,GO:0005158//insulin receptor binding;GO:0005515//protein binding,K14752//Measles
79931,0,0,0,0,0,0,0,71,22,0,0,0,TNIP3;TNFAIP3 interacting protein 3,-,GO:0071222//cellular response to lipopolysaccharide;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0031593//polyubiquitin binding,K14443//RNA degradation
79932,0,0,0,29,19,12,19,0,24,6,20,0,KIAA0319L;KIAA0319-like,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle,-,GO:0005515//protein binding,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
79933,0,0,0,0,0,27,12,98,33,222,32,0,SYNPO2L;synaptopodin 2-like,GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0030018//Z disc,-,GO:0003779//actin binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism
79934,0,0,0,0,1,13,0,40,39,0,0,0,ADCK4;aarF domain containing kinase 4,GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005886//plasma membrane,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity,-
79935,128,0,0,0,0,0,0,0,11,0,0,0,CNTD2;cyclin N-terminal domain containing 2,-,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding,K06627//Acute myeloid leukemia;Pathways in cancer;Cell cycle;Epstein-Barr virus infection;Progesterone-mediated oocyte maturation;Transcriptional misregulation in cancer
79937,0,0,0,0,0,16,0,0,9,176,8,0,CNTNAP3;contactin associated protein-like 3,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0008037//cell recognition;GO:0007155//cell adhesion,-,K07380//Cell adhesion molecules (CAMs)
79939,0,0,0,7,15,0,22,124,16,0,0,0,"SLC35E1;solute carrier family 35, member E1",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
7994,60,28,1,64,184,3,0,0,65,0,24,0,KAT6A;K(lysine) acetyltransferase 6A,GO:0000786//nucleosome;GO:0016605//PML body;GO:0070776//MOZ/MORF histone acetyltransferase complex;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0006473//protein acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0035162//embryonic hemopoiesis;GO:0030099//myeloid cell differentiation;GO:0003007//heart morphogenesis;GO:0035019//somatic stem cell maintenance;GO:0043966//histone H3 acetylation;GO:0016573//histone acetylation;GO:0035909//aorta morphogenesis;GO:0006323//DNA packaging;GO:0060325//face morphogenesis;GO:0006325//chromatin organization;GO:0006351//transcription, DNA-templated;GO:0090398//cellular senescence;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006334//nucleosome assembly",GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0004402//histone acetyltransferase activity;GO:0016407//acetyltransferase activity,-
79943,1,1,0,0,5,0,0,82,26,0,7,0,ZNF696;zinc finger protein 696,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
79944,4,0,0,0,21,11,0,80,53,0,0,0,L2HGDH;L-2-hydroxyglutarate dehydrogenase,GO:0031305//integral component of mitochondrial inner membrane;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006103//2-oxoglutarate metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0044267//cellular protein metabolic process,GO:0047545//2-hydroxyglutarate dehydrogenase activity,K00109//Butanoate metabolism
79946,0,390,148,299,516,43,12,337,86,0,161,0,C10orf95;chromosome 10 open reading frame 95,-,-,GO:0005515//protein binding,-
79947,0,0,0,15,22,0,1,0,31,0,0,0,DHDDS;dehydrodolichyl diphosphate synthase,GO:0005789//endoplasmic reticulum membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0006489//dolichyl diphosphate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification,"GO:0016765//transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0005515//protein binding",K11778//Terpenoid backbone biosynthesis;Biosynthesis of secondary metabolites
79948,34,0,0,0,0,13,15,0,24,0,9,0,LPPR3;lipid phosphate phosphatase-related protein type 3,GO:0016021//integral component of membrane,GO:0016311//dephosphorylation,GO:0008195//phosphatidate phosphatase activity,K01080//Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Sphingolipid metabolism;Ether lipid metabolism
79949,0,0,0,0,0,0,15,0,60,0,4,0,"PLEKHS1;pleckstrin homology domain containing, family S member 1",-,-,-,K09593//ErbB signaling pathway;Renal cell carcinoma;Neurotrophin signaling pathway;Bacterial invasion of epithelial cells;K08091//Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Chronic myeloid leukemia;Osteoclast differentiation
79953,0,0,0,0,0,0,7,0,6,149,0,0,SYNDIG1;synapse differentiation inducing 1,GO:0043198//dendritic shaft;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0044297//cell body;GO:0043197//dendritic spine;GO:0014069//postsynaptic density;GO:0060076//excitatory synapse;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane,GO:0006886//intracellular protein transport;GO:0009607//response to biotic stimulus;GO:0051965//positive regulation of synapse assembly;GO:0097091//synaptic vesicle clustering,GO:0035254//glutamate receptor binding;GO:0042803//protein homodimerization activity,-
79954,71,0,0,61,23,59,0,0,14,0,18,0,NOL10;nucleolar protein 10,GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
79955,0,0,1,0,3,0,21,0,35,0,0,0,PDZD7;PDZ domain containing 7,GO:0005634//nucleus;GO:0005929//cilium;GO:0005615//extracellular space,-,GO:0005515//protein binding,K08018//MAPK signaling pathway
79956,0,0,0,3,14,24,0,0,16,0,5,0,ERMP1;endoplasmic reticulum metallopeptidase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006508//proteolysis,GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity,-
79957,0,0,0,0,0,0,0,0,21,0,0,0,PAQR6;progestin and adipoQ receptor family member VI,GO:0016021//integral component of membrane,-,GO:0004872//receptor activity,K07297//Adipocytokine signaling pathway
79958,0,347,51,472,860,24,35,545,63,155,773,850,DENND1C;DENN/MADD domain containing 1C,GO:0005829//cytosol;GO:0030136//clathrin-coated vesicle,GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
79959,0,0,0,0,30,0,46,2,7,0,2,0,CEP76;centrosomal protein 76kDa,GO:0005829//cytosol;GO:0005814//centriole;GO:0005813//centrosome;GO:0043234//protein complex,GO:0046599//regulation of centriole replication;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0005515//protein binding,-
79960,2,18,0,20,57,57,12,1,38,0,11,374,JADE1;jade family PHD finger 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0045171//intercellular bridge;GO:0005886//plasma membrane;GO:0000123//histone acetyltransferase complex,"GO:0043966//histone H3 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043982//histone H4-K8 acetylation;GO:0006325//chromatin organization;GO:0030308//negative regulation of cell growth;GO:0006950//response to stress;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0043981//histone H4-K5 acetylation;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0001105//RNA polymerase II transcription coactivator activity,-
79961,1,1,27,0,0,24,2,52,11,0,3,0,DENND2D;DENN/MADD domain containing 2D,GO:0005737//cytoplasm,GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome;K13644//Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
79963,0,0,0,1,22,0,0,0,36,0,0,0,"ABCA11P;ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene",-,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity,K05652//ABC transporters
79966,0,0,0,0,0,0,28,0,26,0,1,0,SCD5;stearoyl-CoA desaturase 5,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006633//fatty acid biosynthetic process;GO:0055114//oxidation-reduction process,GO:0005506//iron ion binding;GO:0004768//stearoyl-CoA 9-desaturase activity,K00507//PPAR signaling pathway;Biosynthesis of unsaturated fatty acids
79968,2,0,0,17,0,5,0,0,7,14,6,0,WDR76;WD repeat domain 76,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K01539//Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
79970,0,0,0,0,0,21,26,0,0,0,0,0,"ZNF767P;zinc finger family member 767, pseudogene",-,-,-,-
79971,85,0,0,10,0,19,0,0,0,233,0,0,WLS;wntless Wnt ligand secretion mediator,GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0000139//Golgi membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane,GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001707//mesoderm formation;GO:0009948//anterior/posterior axis specification;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0016055//Wnt signaling pathway,GO:0004871//signal transducer activity;GO:0017147//Wnt-protein binding;GO:0005515//protein binding,-
79973,0,0,0,0,15,44,0,0,0,0,8,0,ZNF442;zinc finger protein 442,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79974,0,0,0,0,0,52,46,38,38,116,0,0,CPED1;cadherin-like and PC-esterase domain containing 1,GO:0005783//endoplasmic reticulum,-,-,-
79977,0,93,2,107,284,16,1,0,104,0,28,0,GRHL2;grainyhead-like 2 (Drosophila),GO:0005634//nucleus,"GO:0060324//face development;GO:0007420//brain development;GO:0060463//lung lobe morphogenesis;GO:0035264//multicellular organism growth;GO:0006351//transcription, DNA-templated;GO:0042733//embryonic digit morphogenesis;GO:0001843//neural tube closure;GO:0043010//camera-type eye development;GO:0006355//regulation of transcription, DNA-templated;GO:0003208//cardiac ventricle morphogenesis;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0001701//in utero embryonic development",GO:0003677//DNA binding,-
79979,0,0,0,10,56,0,0,48,1,0,0,0,TRMT2B;tRNA methyltransferase 2 homolog B (S. cerevisiae),GO:0005739//mitochondrion,GO:0008033//tRNA processing;GO:0032259//methylation,GO:0030697//S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity,-
79980,0,0,0,19,2,0,0,0,4,0,9,0,"DSN1;DSN1, MIS12 kinetochore complex component",GO:0005829//cytosol;GO:0005634//nucleus;GO:0000444//MIS12/MIND type complex,GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation,GO:0005515//protein binding,-
79981,0,0,0,0,0,27,14,43,74,0,0,0,FRMD1;FERM domain containing 1,GO:0005856//cytoskeleton,-,-,-
79982,0,1,0,1,51,22,0,0,44,0,0,0,"DNAJB14;DnaJ (Hsp40) homolog, subfamily B, member 14",GO:0016020//membrane;GO:0016021//integral component of membrane,-,-,-
79983,155,0,0,0,0,0,0,0,28,0,0,0,"POF1B;premature ovarian failure, 1B",GO:0005923//tight junction,-,GO:0003779//actin binding,K04514//Axon guidance;Chemokine signaling pathway;Salmonella infection;Shigellosis;TGF-beta signaling pathway;Leukocyte transendothelial migration;Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Focal adhesion
79986,0,24,0,39,9,0,0,0,11,0,0,0,"ZNF702P;zinc finger protein 702, pseudogene",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
79987,121,0,0,0,0,63,21,66,62,0,12,0,"SVEP1;sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005576//extracellular region,GO:0007155//cell adhesion,GO:0005509//calcium ion binding;GO:0003682//chromatin binding,K04011//Malaria;Leishmaniasis;Hematopoietic cell lineage;Tuberculosis;Legionellosis;Complement and coagulation cascades
79989,0,0,0,0,13,0,3,0,26,0,0,0,TTC26;tetratricopeptide repeat domain 26,GO:0030992//intraciliary transport particle B;GO:0072372//primary cilium;GO:0036064//ciliary basal body;GO:0005813//centrosome,GO:0042384//cilium assembly,-,K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;Metabolic pathways;beta-Alanine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
79990,0,0,1,0,0,0,12,0,21,0,4,2,"PLEKHH3;pleckstrin homology domain containing, family H (with MyTH4 domain) member 3",GO:0005856//cytoskeleton;GO:0005615//extracellular space,GO:0007165//signal transduction,-,K12559//Fc gamma R-mediated phagocytosis
79991,10,0,0,12,0,0,19,0,6,0,3,0,OBFC1;oligonucleotide/oligosaccharide-binding fold containing 1,"GO:0005634//nucleus;GO:0070188//Stn1-Ten1 complex;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0000784//nuclear chromosome, telomeric region",GO:0000723//telomere maintenance;GO:0010833//telomere maintenance via telomere lengthening;GO:0045740//positive regulation of DNA replication,GO:0043047//single-stranded telomeric DNA binding;GO:0003697//single-stranded DNA binding;GO:0005515//protein binding,-
79993,0,2,0,24,63,0,0,34,0,0,0,204,ELOVL7;ELOVL fatty acid elongase 7,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,"GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0044281//small molecule metabolic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process",GO:0016740//transferase activity;GO:0005515//protein binding,K10250//Fatty acid elongation
79998,0,0,0,0,0,0,1,0,26,0,0,0,ANKRD53;ankyrin repeat domain 53,-,-,-,-
800,156,29,1,116,243,0,28,0,26,0,11,0,CALD1;caldesmon 1,GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0030478//actin cap;GO:0005886//plasma membrane;GO:0030016//myofibril,GO:0006928//cellular component movement;GO:0006936//muscle contraction,GO:0017022//myosin binding;GO:0005523//tropomyosin binding;GO:0003779//actin binding;GO:0005516//calmodulin binding,K12327//Vascular smooth muscle contraction
8000,0,0,0,0,1,0,19,0,0,0,0,3,PSCA;prostate stem cell antigen,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031225//anchored component of membrane,-,-,-
80000,0,0,1,14,0,0,82,97,53,26,14,0,GREB1L;growth regulation by estrogen in breast cancer-like,GO:0016021//integral component of membrane,-,-,-
80003,0,0,0,0,27,11,21,33,74,103,30,0,PCNXL2;pecanex-like 2 (Drosophila),GO:0016021//integral component of membrane,-,-,-
80004,33,17,1,29,127,16,0,0,29,0,8,0,ESRP2;epithelial splicing regulatory protein 2,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0043484//regulation of RNA splicing;GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003729//mRNA binding,-
80005,94,17,0,38,127,17,24,52,54,0,0,0,DOCK5;dedicator of cytokinesis 5,GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity,-
80006,0,0,0,59,43,0,8,0,0,0,0,0,TRAPPC13;trafficking protein particle complex 13,-,-,GO:0005515//protein binding,-
80007,0,0,0,0,0,10,0,0,46,0,0,0,C10orf88;chromosome 10 open reading frame 88,-,-,GO:0042802//identical protein binding,-
80008,0,0,0,0,0,12,0,0,19,0,2,0,TMEM156;transmembrane protein 156,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
8001,0,0,0,0,0,45,36,0,53,0,26,0,"GLRA3;glycine receptor, alpha 3",GO:0045211//postsynaptic membrane;GO:0034707//chloride channel complex;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005887//integral component of plasma membrane,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport,GO:0016594//glycine binding;GO:0022824//transmitter-gated ion channel activity;GO:0016934//extracellular-glycine-gated chloride channel activity,K05195//Neuroactive ligand-receptor interaction
80010,9,0,0,18,51,0,0,14,98,0,0,0,RMI1;RecQ mediated genome instability 1,GO:0005634//nucleus,GO:0009749//response to glucose;GO:0035264//multicellular organism growth;GO:0042593//glucose homeostasis;GO:0006260//DNA replication;GO:0002023//reduction of food intake in response to dietary excess,GO:0005515//protein binding,K10990//Fanconi anemia pathway
80011,0,1,0,15,85,37,0,0,21,0,0,0,"FAM192A;family with sequence similarity 192, member A",GO:0005634//nucleus,-,-,-
80012,0,109,41,149,398,3,0,1,79,0,45,0,PHC3;polyhomeotic homolog 3 (Drosophila),GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0015629//actin cytoskeleton;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex;GO:0005730//nucleolus,GO:0007275//multicellular organismal development,GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
80013,0,15,0,16,31,0,0,0,56,0,0,0,"FAM188A;family with sequence similarity 188, member A",GO:0005634//nucleus,GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0005509//calcium ion binding,-
80014,0,2,0,6,101,35,0,1,46,0,1,0,WWC2;WW and C2 domain containing 2,GO:0005829//cytosol,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046621//negative regulation of organ growth;GO:0035331//negative regulation of hippo signaling,GO:0032947//protein complex scaffold;GO:0019900//kinase binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
80017,0,11,0,4,4,0,35,0,42,0,0,0,C14orf159;chromosome 14 open reading frame 159,GO:0005739//mitochondrion,-,-,-
80018,78,0,0,11,13,19,59,112,10,0,4,0,"NAA25;N(alpha)-acetyltransferase 25, NatB auxiliary subunit",GO:0005737//cytoplasm,-,-,-
80019,0,0,0,0,0,0,44,109,0,0,0,0,UBTD1;ubiquitin domain containing 1,-,-,-,-
80020,36,15,0,3,9,55,28,46,17,0,14,0,FOXRED2;FAD-dependent oxidoreductase domain containing 2,GO:0005788//endoplasmic reticulum lumen,GO:0055114//oxidation-reduction process;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0016491//oxidoreductase activity;GO:0005515//protein binding;GO:0050660//flavin adenine dinucleotide binding;GO:0001948//glycoprotein binding,K11447//Transcriptional misregulation in cancer
80021,0,1,0,0,12,0,0,0,0,0,0,0,TMEM62;transmembrane protein 62,GO:0016021//integral component of membrane,-,-,-
80022,0,1,3,1,3,3,17,7,65,0,23,0,MYO15B;myosin XVB pseudogene,-,-,-,-
80023,0,0,1,0,20,0,0,0,47,0,0,0,NRSN2;neurensin 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030133//transport vesicle;GO:0043025//neuronal cell body,-,-,-
80024,0,0,0,0,0,47,12,0,0,0,0,0,"SLC8B1;solute carrier family 8 (sodium/lithium/calcium exchanger), member B1",GO:0042383//sarcolemma;GO:0005886//plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0032592//integral component of mitochondrial membrane,GO:0042593//glucose homeostasis;GO:0006851//mitochondrial calcium ion transport;GO:0050896//response to stimulus;GO:0006811//ion transport;GO:0050796//regulation of insulin secretion;GO:0035725//sodium ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0055085//transmembrane transport,GO:0005432//calcium:sodium antiporter activity,-
80025,0,0,0,22,68,0,0,0,23,0,18,0,PANK2;pantothenate kinase 2,GO:0005758//mitochondrial intermembrane space;GO:0005829//cytosol,GO:0015937//coenzyme A biosynthetic process;GO:0006766//vitamin metabolic process;GO:0051881//regulation of mitochondrial membrane potential;GO:0015939//pantothenate metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0009060//aerobic respiration;GO:0016310//phosphorylation;GO:0070584//mitochondrion morphogenesis;GO:0008219//cell death;GO:0007286//spermatid development;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0004594//pantothenate kinase activity;GO:0005524//ATP binding,K09680//Pantothenate and CoA biosynthesis;Metabolic pathways
80028,0,0,0,0,18,11,40,0,27,137,11,403,FBXL18;F-box and leucine-rich repeat protein 18,-,-,-,-
80031,65,0,0,0,0,13,2,0,24,0,8,0,"SEMA6D;sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D",GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0021591//ventricular system development;GO:0007411//axon guidance;GO:0014911//positive regulation of smooth muscle cell migration;GO:0014912//negative regulation of smooth muscle cell migration,GO:0030215//semaphorin receptor binding;GO:0004872//receptor activity,K06842//Axon guidance
80034,0,0,0,0,14,30,0,40,50,0,25,270,CSRNP3;cysteine-serine-rich nuclear protein 3,GO:0005634//nucleus,"GO:0010923//negative regulation of phosphatase activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
80036,0,0,0,0,6,11,27,0,98,0,0,0,"TRPM3;transient receptor potential cation channel, subfamily M, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050951//sensory perception of temperature stimulus;GO:0006812//cation transport;GO:0034220//ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0016048//detection of temperature stimulus;GO:0055085//transmembrane transport,GO:0005262//calcium channel activity;GO:0005227//calcium activated cation channel activity;GO:0005261//cation channel activity,-
80055,0,2,0,0,0,10,16,0,41,0,0,0,PGAP1;post-GPI attachment to proteins 1,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0060322//head development;GO:0044267//cellular protein metabolic process;GO:0009880//embryonic pattern specification;GO:0021871//forebrain regionalization;GO:0006501//C-terminal protein lipidation;GO:0016255//attachment of GPI anchor to protein;GO:0007605//sensory perception of sound;GO:0043687//post-translational protein modification;GO:0015798//myo-inositol transport;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006886//intracellular protein transport;GO:0009948//anterior/posterior axis specification,GO:0042578//phosphoric ester hydrolase activity;GO:0004518//nuclease activity,K05294//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
80059,0,0,0,0,0,0,1,0,18,0,0,0,LRRTM4;leucine rich repeat transmembrane neuronal 4,GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0097113//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering,GO:0043395//heparan sulfate proteoglycan binding,K06248//Focal adhesion;ECM-receptor interaction
80063,6,0,0,5,0,0,4,0,6,0,0,0,ATF7IP2;activating transcription factor 7 interacting protein 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,K01539//Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
80067,0,0,0,9,24,0,0,0,11,0,19,0,DCAF17;DDB1 and CUL4 associated factor 17,GO:0005730//nucleolus;GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0016021//integral component of membrane,GO:0016567//protein ubiquitination,-,K10415//Salmonella infection;Vasopressin-regulated water reabsorption;Phagosome
80070,0,0,0,0,0,62,56,0,50,0,0,0,"ADAMTS20;ADAM metallopeptidase with thrombospondin type 1 motif, 20",GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space,GO:0045636//positive regulation of melanocyte differentiation;GO:0009967//positive regulation of signal transduction;GO:0006508//proteolysis;GO:0043066//negative regulation of apoptotic process;GO:0030198//extracellular matrix organization,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding,-
80071,0,0,0,11,18,0,0,0,7,0,0,0,CCDC15;coiled-coil domain containing 15,GO:0005813//centrosome,-,-,K03006//Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Herpes simplex infection;Huntington's disease;Metabolic pathways
80072,0,0,55,5,34,0,0,0,0,154,15,1,HEXA-AS1;HEXA antisense RNA 1,-,-,-,-
80086,0,0,0,0,0,16,0,0,18,167,0,0,"TUBA4B;tubulin, alpha 4b (pseudogene)",GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0007017//microtubule-based process,GO:0005525//GTP binding;GO:0005200//structural constituent of cytoskeleton,K07374//Phagosome;Gap junction;Pathogenic Escherichia coli infection
80095,0,49,3,8,47,0,58,0,6,0,22,0,ZNF606;zinc finger protein 606,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
80097,0,0,1,1,8,0,0,0,0,0,23,0,MZT2B;mitotic spindle organizing protein 2B,GO:0005813//centrosome;GO:0008274//gamma-tubulin ring complex;GO:0005819//spindle,-,GO:0005515//protein binding,-
80099,0,0,0,0,0,0,0,25,0,0,0,0,C7orf69;chromosome 7 open reading frame 69,GO:0005576//extracellular region,-,-,-
801,0,229,7,295,1027,0,24,0,19,0,2,571,"CALM1;calmodulin 1 (phosphorylase kinase, delta)",-,-,-,K02183//Olfactory transduction;Calcium signaling pathway;Salivary secretion;Neurotrophin signaling pathway;Alzheimer's disease;Gastric acid secretion;Glioma;Melanogenesis;GnRH signaling pathway;Phosphatidylinositol signaling system;Dopaminergic synapse;Insulin signaling pathway;Phototransduction;Alcoholism;Tuberculosis;Pertussis;Long-term potentiation;Amphetamine addiction;Vascular smooth muscle contraction;Oocyte meiosis;Phototransduction - fly;Plant-pathogen interaction
80108,0,0,0,0,0,28,0,0,7,0,0,0,ZFP2;ZFP2 zinc finger protein,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
80110,0,41,35,94,112,0,42,0,39,0,34,0,ZNF614;zinc finger protein 614,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
80111,0,0,0,0,0,0,0,0,0,100,0,0,C3orf36;chromosome 3 open reading frame 36,-,-,-,-
80114,0,1,0,0,1,36,35,62,57,0,0,0,BICC1;BicC family RNA binding protein 1,GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0090090//negative regulation of canonical Wnt signaling pathway,GO:0044822//poly(A) RNA binding,K12889//Spliceosome
80115,0,0,0,8,0,0,33,125,40,0,15,0,BAIAP2L2;BAI1-associated protein 2-like 2,GO:0012506//vesicle membrane;GO:0071439//clathrin complex;GO:0030659//cytoplasmic vesicle membrane;GO:0044291//cell-cell contact zone;GO:0005886//plasma membrane,GO:0061024//membrane organization;GO:0007165//signal transduction;GO:0032956//regulation of actin cytoskeleton organization;GO:0046847//filopodium assembly,GO:0017124//SH3 domain binding;GO:0005543//phospholipid binding;GO:0008093//cytoskeletal adaptor activity,K05627//Regulation of actin cytoskeleton;Adherens junction
80119,0,0,0,0,0,0,0,0,42,0,14,0,PIF1;PIF1 5'-to-3' DNA helicase,"GO:0000784//nuclear chromosome, telomeric region;GO:0005739//mitochondrion",GO:0000002//mitochondrial genome maintenance;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0006310//DNA recombination;GO:0032211//negative regulation of telomere maintenance via telomerase;GO:0032204//regulation of telomere maintenance;GO:0051974//negative regulation of telomerase activity;GO:0032508//DNA duplex unwinding;GO:0000723//telomere maintenance,GO:0033682//ATP-dependent 5'-3' DNA/RNA helicase activity;GO:0005524//ATP binding;GO:0017116//single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0043141//ATP-dependent 5'-3' DNA helicase activity;GO:0042162//telomeric DNA binding;GO:0051880//G-quadruplex DNA binding;GO:0010521//telomerase inhibitor activity;GO:0000287//magnesium ion binding,-
80122,30,31,0,0,0,37,56,0,14,0,0,0,MAP3K19;mitogen-activated protein kinase kinase kinase 19,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K04420//Gap junction;MAPK signaling pathway;GnRH signaling pathway;K04421//HTLV-I infection;Neurotrophin signaling pathway;MAPK signaling pathway;GnRH signaling pathway
80124,0,51,0,22,128,9,20,0,39,0,1,0,VCPIP1;valosin containing protein (p97)/p47 complex interacting protein 1,GO:0005783//endoplasmic reticulum;GO:0005795//Golgi stack;GO:0005737//cytoplasm,GO:0007067//mitotic nuclear division;GO:0006508//proteolysis;GO:0035871//protein K11-linked deubiquitination;GO:0016567//protein ubiquitination;GO:0016320//endoplasmic reticulum membrane fusion;GO:0090168//Golgi reassembly;GO:0071108//protein K48-linked deubiquitination,GO:0004843//ubiquitin-specific protease activity,-
80125,0,0,0,2,0,12,36,2,2,0,0,0,CCDC33;coiled-coil domain containing 33,-,-,GO:0005515//protein binding,-
80127,93,1177,793,1353,1925,0,23,206,111,1,1834,634,CCDC176;coiled-coil domain containing 176,GO:0005737//cytoplasm;GO:0036064//ciliary basal body,GO:0044458//motile cilium assembly,-,"K00140//Inositol phosphate metabolism;Propanoate metabolism;beta-Alanine metabolism;Metabolic pathways;Valine, leucine and isoleucine degradation"
80128,1,0,0,0,2,0,27,10,29,6,10,0,TRIM46;tripartite motif containing 46,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
80129,0,0,0,0,0,16,0,1,20,0,15,0,CCDC170;coiled-coil domain containing 170,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
8013,90,0,25,0,0,1,0,0,76,0,7,0,"NR4A3;nuclear receptor subfamily 4, group A, member 3",GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0030522//intracellular receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression",GO:0004887//thyroid hormone receptor activity;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003707//steroid hormone receptor activity;GO:0003677//DNA binding,K08559//Transcriptional misregulation in cancer
80131,0,0,0,0,0,49,0,72,70,0,0,0,"LRRC8E;leucine rich repeat containing 8 family, member E",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006811//ion transport,GO:0005515//protein binding,K01768//Purine metabolism;Meiosis - yeast;K10130//p53 signaling pathway;NF-kappa B signaling pathway
80133,0,0,0,0,0,0,27,0,63,0,0,0,MROH9;maestro heat-like repeat family member 9,-,-,-,-
80135,0,16,1,44,23,0,0,0,26,0,0,0,RPF1;ribosome production factor 1 homolog (S. cerevisiae),GO:0005730//nucleolus,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding;GO:0019843//rRNA binding;GO:0003723//RNA binding,-
80139,0,0,0,13,0,0,0,0,2,0,16,0,ZNF703;zinc finger protein 703,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0043234//protein complex,"GO:0060828//regulation of canonical Wnt signaling pathway;GO:0060644//mammary gland epithelial cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0034111//negative regulation of homotypic cell-cell adhesion;GO:0030335//positive regulation of cell migration;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0071392//cellular response to estradiol stimulus;GO:0033601//positive regulation of mammary gland epithelial cell proliferation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034333//adherens junction assembly",GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0070491//repressing transcription factor binding,-
80142,0,0,0,0,0,31,0,51,32,0,6,0,PTGES2;prostaglandin E synthase 2,GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0046903//secretion;GO:0045454//cell redox homeostasis;GO:0001516//prostaglandin biosynthetic process;GO:0055114//oxidation-reduction process;GO:0045893//positive regulation of transcription, DNA-templated",GO:0015035//protein disulfide oxidoreductase activity;GO:0009055//electron carrier activity;GO:0050220//prostaglandin-E synthase activity;GO:0016829//lyase activity;GO:0003677//DNA binding;GO:0043295//glutathione binding;GO:0020037//heme binding,K05309//Arachidonic acid metabolism;Metabolic pathways
80143,190,1,1,12,57,16,16,68,26,1,25,0,SIKE1;suppressor of IKBKE 1,GO:0005829//cytosol,GO:0045087//innate immune response,GO:0005515//protein binding,K12656//RIG-I-like receptor signaling pathway
80144,66,0,0,0,5,50,75,108,189,535,15,1,FRAS1;Fraser extracellular matrix complex subunit 1,GO:0031012//extracellular matrix;GO:0061618//sublamina densa;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0060021//palate development;GO:0015031//protein transport;GO:0002009//morphogenesis of an epithelium;GO:0030326//embryonic limb morphogenesis;GO:0007154//cell communication;GO:0003338//metanephros morphogenesis;GO:0043588//skin development,GO:0046872//metal ion binding,-
80145,0,1,0,13,20,22,0,0,17,0,0,0,THOC7;THO complex 7 homolog (Drosophila),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000445//THO complex part of transcription export complex;GO:0005730//nucleolus;GO:0000346//transcription export complex;GO:0016607//nuclear speck,GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0046784//viral mRNA export from host cell nucleus;GO:0006406//mRNA export from nucleus,GO:0003723//RNA binding;GO:0005515//protein binding,K13176//RNA transport
80146,0,0,0,0,11,0,0,0,49,0,0,0,UXS1;UDP-glucuronate decarboxylase 1,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0005739//mitochondrion,GO:0033320//UDP-D-xylose biosynthetic process;GO:0051262//protein tetramerization,GO:0042803//protein homodimerization activity;GO:0048040//UDP-glucuronate decarboxylase activity;GO:0070403//NAD+ binding,K08678//Amino sugar and nucleotide sugar metabolism;Starch and sucrose metabolism;Metabolic pathways
80148,0,0,0,0,0,0,20,0,8,10,0,0,PQLC1;PQ loop repeat containing 1,GO:0016021//integral component of membrane,-,-,-
80149,0,0,0,0,0,0,0,1,0,0,0,0,ZC3H12A;zinc finger CCCH-type containing 12A,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0032715//negative regulation of interleukin-6 production;GO:0030154//cell differentiation;GO:0045600//positive regulation of fat cell differentiation;GO:0071222//cellular response to lipopolysaccharide;GO:0043031//negative regulation of macrophage activation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0006915//apoptotic process;GO:0032720//negative regulation of tumor necrosis factor production;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0010629//negative regulation of gene expression;GO:0010884//positive regulation of lipid storage;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0010508//positive regulation of autophagy;GO:0001525//angiogenesis;GO:0010628//positive regulation of gene expression,GO:0004519//endonuclease activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
80150,0,20,0,24,16,0,31,0,4,0,16,0,ASRGL1;asparaginase like 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006508//proteolysis;GO:0033345//asparagine catabolic process via L-aspartate,GO:0008798//beta-aspartyl-peptidase activity;GO:0003948//N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity;GO:0004067//asparaginase activity,-
80152,261,63,2,53,85,0,0,0,54,0,69,0,CENPT;centromere protein T,"GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus",GO:0051276//chromosome organization;GO:0007059//chromosome segregation;GO:0000278//mitotic cell cycle;GO:0051382//kinetochore assembly;GO:0007067//mitotic nuclear division,GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
80153,111,0,0,15,54,18,0,0,52,0,12,1,EDC3;enhancer of mRNA decapping 3,GO:0016020//membrane;GO:0005829//cytosol;GO:0000932//cytoplasmic mRNA processing body,"GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010467//gene expression;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0043928//exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K12615//RNA degradation
80154,0,0,0,0,0,2,0,0,17,0,0,0,LOC80154;golgin A2 pseudogene,-,-,-,K01528//Endocytosis;Bacterial invasion of epithelial cells;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Synaptic vesicle cycle
80155,99,39,0,27,52,0,17,0,61,84,30,1,"NAA15;N(alpha)-acetyltransferase 15, NatA auxiliary subunit",GO:0016020//membrane;GO:0031415//NatA complex;GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0001525//angiogenesis;GO:0050821//protein stabilization;GO:0043066//negative regulation of apoptotic process;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006474//N-terminal protein amino acid acetylation",GO:0016407//acetyltransferase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008080//N-acetyltransferase activity;GO:0043022//ribosome binding,-
80157,1,0,0,0,18,0,28,0,25,0,20,0,CWH43;cell wall biogenesis 43 C-terminal homolog (S. cerevisiae),GO:0016021//integral component of membrane,GO:0006506//GPI anchor biosynthetic process,-,-
80161,69,2,0,0,1,0,0,0,8,0,14,0,ASMTL-AS1;ASMTL antisense RNA 1,-,-,-,K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
80162,0,0,0,0,8,0,42,54,13,0,17,0,"ATHL1;ATH1, acid trehalase-like 1 (yeast)",-,GO:0005975//carbohydrate metabolic process,"GO:0016798//hydrolase activity, acting on glycosyl bonds",K06566//B cell receptor signaling pathway
80164,44,0,1,0,0,0,0,49,29,0,7,10,FLJ22184;putative uncharacterized protein FLJ22184,-,-,-,K03006//Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism;Metabolic pathways;Huntington's disease;Herpes simplex infection
80167,0,0,0,0,24,28,24,0,37,79,1,0,C4orf29;chromosome 4 open reading frame 29,GO:0005576//extracellular region,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;Metabolic pathways;beta-Alanine metabolism
80168,0,0,0,0,0,0,0,58,8,0,0,0,MOGAT2;monoacylglycerol O-acyltransferase 2,GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0019432//triglyceride biosynthetic process;GO:0006071//glycerol metabolic process;GO:0006651//diacylglycerol biosynthetic process;GO:0050892//intestinal absorption,GO:0016407//acetyltransferase activity;GO:0003846//2-acylglycerol O-acyltransferase activity,K14457//Fat digestion and absorption
80169,46,0,0,16,2,13,17,75,13,0,0,0,CTC1;CTS telomere maintenance complex component 1,"GO:0000784//nuclear chromosome, telomeric region;GO:0070188//Stn1-Ten1 complex;GO:0005634//nucleus",GO:0048146//positive regulation of fibroblast proliferation;GO:0045740//positive regulation of DNA replication;GO:0000723//telomere maintenance;GO:0090399//replicative senescence;GO:0035264//multicellular organism growth;GO:0071425//hematopoietic stem cell proliferation;GO:0048536//spleen development;GO:0048539//bone marrow development;GO:0010833//telomere maintenance via telomere lengthening;GO:0006974//cellular response to DNA damage stimulus;GO:0048538//thymus development;GO:0010389//regulation of G2/M transition of mitotic cell cycle,GO:0005515//protein binding;GO:0003697//single-stranded DNA binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K14443//RNA degradation;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion
80173,77,116,15,71,179,0,0,547,18,0,104,432,IFT74;intraflagellar transport 74,GO:0005929//cilium;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B;GO:0005813//centrosome;GO:0005634//nucleus,GO:0035735//intraciliary transport involved in cilium morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003334//keratinocyte development;GO:0050680//negative regulation of epithelial cell proliferation;GO:0042384//cilium assembly;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0007219//Notch signaling pathway,GO:0003682//chromatin binding;GO:0048487//beta-tubulin binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;K12478//Tuberculosis;Endocytosis;Phagosome
80174,0,40,0,0,0,0,13,0,36,0,8,0,DBF4B;DBF4 zinc finger B,GO:0043231//intracellular membrane-bounded organelle;GO:0016235//aggresome;GO:0005737//cytoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0045860//positive regulation of protein kinase activity;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0007049//cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle,GO:0019901//protein kinase binding;GO:0008270//zinc ion binding;GO:0003676//nucleic acid binding;GO:0030295//protein kinase activator activity,K06629//Cell cycle
80176,32,1,0,3,0,0,0,2,0,0,13,0,SPSB1;splA/ryanodine receptor domain and SOCS box containing 1,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,GO:0005515//protein binding,-
80177,0,0,0,0,8,0,0,0,5,0,0,0,MYCT1;myc target 1,GO:0005634//nucleus,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
80178,0,0,0,0,0,0,0,0,13,0,0,0,C16orf59;chromosome 16 open reading frame 59,-,-,-,-
80179,0,37,0,10,27,0,33,0,30,0,59,0,MYO19;myosin XIX,GO:0016459//myosin complex;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane,GO:0008152//metabolic process,GO:0003779//actin binding;GO:0005524//ATP binding;GO:0003774//motor activity,-
80183,221,0,0,0,0,0,89,0,65,0,0,0,KIAA0226L;KIAA0226-like,-,-,-,-
80184,17,23,54,86,47,1,156,0,125,310,20,0,CEP290;centrosomal protein 290kDa,GO:0043234//protein complex;GO:0005813//centrosome;GO:0036038//TCTN-B9D complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0000930//gamma-tubulin complex;GO:0032391//photoreceptor connecting cilium;GO:0005634//nucleus;GO:0005829//cytosol;GO:0034451//centriolar satellite,"GO:0042462//eye photoreceptor cell development;GO:0070201//regulation of establishment of protein localization;GO:0030814//regulation of cAMP metabolic process;GO:0060041//retina development in camera-type eye;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060271//cilium morphogenesis;GO:0030902//hindbrain development;GO:0030916//otic vesicle formation;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0042384//cilium assembly;GO:0048793//pronephros development;GO:0007163//establishment or maintenance of cell polarity;GO:0015031//protein transport;GO:0090316//positive regulation of intracellular protein transport",GO:0051011//microtubule minus-end binding;GO:0005515//protein binding,-
80185,0,51,29,183,187,12,1,0,23,0,269,1,TTI2;TELO2 interacting protein 2,-,-,-,-
8019,91,30,0,0,66,24,12,0,0,0,37,0,BRD3;bromodomain containing 3,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0005515//protein binding,-
80194,0,0,0,0,3,16,0,0,0,0,0,0,TMEM134;transmembrane protein 134,GO:0016021//integral component of membrane,-,-,-
80196,0,0,0,17,17,1,30,0,0,29,0,0,"RNF34;ring finger protein 34, E3 ubiquitin protein ligase",GO:0012505//endomembrane system;GO:0005886//plasma membrane;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:2001271//negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0016567//protein ubiquitination;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0070936//protein K48-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1901797//negative regulation of signal transduction by p53 class mediator;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process",GO:0016874//ligase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0061630//ubiquitin protein ligase activity;GO:1901981//phosphatidylinositol phosphate binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding,K16061//Small cell lung cancer;Ubiquitin mediated proteolysis;Pathways in cancer;Apoptosis;Toxoplasmosis;K10871//Homologous recombination
80198,0,1,0,6,42,0,25,87,42,0,20,0,MUS81;MUS81 structure-specific endonuclease subunit,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006281//DNA repair;GO:0006310//DNA recombination;GO:0000737//DNA catabolic process, endonucleolytic",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0048257//3'-flap endonuclease activity,K08991//Fanconi anemia pathway;Homologous recombination
80199,0,213,19,86,145,0,0,362,44,0,182,0,FUZ;fuzzy planar cell polarity protein,GO:0070062//extracellular vesicular exosome;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0001942//hair follicle development;GO:0045724//positive regulation of cilium assembly;GO:0090301//negative regulation of neural crest formation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0001736//establishment of planar polarity;GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0015031//protein transport;GO:0008589//regulation of smoothened signaling pathway;GO:0010172//embryonic body morphogenesis;GO:0001843//neural tube closure;GO:0035058//nonmotile primary cilium assembly;GO:0021513//spinal cord dorsal/ventral patterning;GO:2000314//negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0048704//embryonic skeletal system morphogenesis;GO:0042384//cilium assembly,-,K12617//RNA degradation
80201,0,0,0,0,0,33,0,5,37,0,0,0,HKDC1;hexokinase domain containing 1,GO:0005829//cytosol,GO:0006096//glycolytic process;GO:0046835//carbohydrate phosphorylation;GO:0019318//hexose metabolic process;GO:0001678//cellular glucose homeostasis;GO:0051156//glucose 6-phosphate metabolic process,GO:0019158//mannokinase activity;GO:0008865//fructokinase activity;GO:0005524//ATP binding;GO:0004340//glucokinase activity,K00844//Insulin signaling pathway;Microbial metabolism in diverse environments;Streptomycin biosynthesis;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Butirosin and neomycin biosynthesis;Starch and sucrose metabolism;Carbohydrate digestion and absorption;Fructose and mannose metabolism;Metabolic pathways;Galactose metabolism;Type II diabetes mellitus
80204,0,0,0,10,32,0,0,11,69,0,0,0,FBXO11;F-box protein 11,GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005694//chromosome,GO:0016567//protein ubiquitination;GO:0006464//cellular protein modification process;GO:0007605//sensory perception of sound;GO:0035246//peptidyl-arginine N-methylation;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016274//protein-arginine N-methyltransferase activity;GO:0008270//zinc ion binding,-
80205,0,28,2,11,116,80,29,0,101,0,1,0,CHD9;chromodomain helicase DNA binding protein 9,GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding,-
80206,22,19,1,0,0,59,4,73,7,0,28,366,FHOD3;formin homology 2 domain containing 3,GO:0005865//striated muscle thin filament;GO:0030018//Z disc,GO:0045214//sarcomere organization;GO:0055003//cardiac myofibril assembly;GO:0030837//negative regulation of actin filament polymerization;GO:0051639//actin filament network formation,GO:0003779//actin binding;GO:0005515//protein binding,K04512//Wnt signaling pathway;K05745//Regulation of actin cytoskeleton;K05740//Focal adhesion;Shigellosis;Regulation of actin cytoskeleton
80207,78,0,0,0,9,0,42,22,68,0,7,308,"OPA3;optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)",GO:0005739//mitochondrion,GO:0050905//neuromuscular process;GO:0070584//mitochondrion morphogenesis;GO:0007601//visual perception;GO:0019216//regulation of lipid metabolic process;GO:0040007//growth;GO:0050896//response to stimulus,-,K11447//Transcriptional misregulation in cancer
80208,0,121,53,172,431,23,23,134,45,0,250,125,SPG11;spastic paraplegia 11 (autosomal recessive),GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0008219//cell death,GO:0005515//protein binding,-
80209,0,25,0,32,30,0,48,0,26,0,0,0,PROSER1;proline and serine rich 1,-,-,-,-
8021,0,26,0,4,72,43,2,0,103,73,12,0,NUP214;nucleoporin 214kDa,GO:0005925//focal adhesion;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0055085//transmembrane transport;GO:0051726//regulation of cell cycle;GO:0010467//gene expression;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0006406//mRNA export from nucleus;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0006611//protein export from nucleus;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006606//protein import into nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0010827//regulation of glucose transport,GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding;GO:0005215//transporter activity,K14317//Epstein-Barr virus infection;RNA transport
80210,213,0,0,0,2,68,66,40,70,0,0,0,ARMC9;armadillo repeat containing 9,GO:0070062//extracellular vesicular exosome,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
80212,97,0,13,27,26,0,0,1,0,0,2,0,CCDC92;coiled-coil domain containing 92,GO:0005814//centriole,-,GO:0005515//protein binding,-
80213,0,0,0,0,0,0,2,0,0,1,0,0,TM2D3;TM2 domain containing 3,GO:0016021//integral component of membrane,-,-,K03511//Fanconi anemia pathway
80216,98,0,0,0,14,7,2,40,50,0,0,0,ALPK1;alpha-kinase 1,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
80217,0,0,1,10,0,52,0,0,78,43,3,0,WDR96;WD repeat domain 96,-,-,-,-
80218,0,56,3,223,666,1,18,0,17,0,15,219,"NAA50;N(alpha)-acetyltransferase 50, NatE catalytic subunit",GO:0031415//NatA complex;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,"GO:0006474//N-terminal protein amino acid acetylation;GO:0071962//mitotic sister chromatid cohesion, centromeric;GO:0043967//histone H4 acetylation","GO:0005515//protein binding;GO:0052858//peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity",K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
80219,0,0,0,27,39,15,0,0,0,0,0,0,COQ10B;coenzyme Q10 homolog B (S. cerevisiae),GO:0005743//mitochondrial inner membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
8022,80,0,0,7,0,0,0,0,12,0,0,0,LHX3;LIM homeobox 3,GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0048839//inner ear development;GO:0021983//pituitary gland development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0021526//medial motor column neuron differentiation;GO:0021520//spinal cord motor neuron cell fate specification;GO:0021521//ventral spinal cord interneuron specification;GO:0009887//organ morphogenesis;GO:0001890//placenta development;GO:0043066//negative regulation of apoptotic process;GO:0021527//spinal cord association neuron differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0008045//motor neuron axon guidance;GO:0030324//lung development",GO:0008270//zinc ion binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
80221,0,0,0,0,8,0,0,46,4,0,0,0,ACSF2;acyl-CoA synthetase family member 2,GO:0005739//mitochondrion,GO:0006631//fatty acid metabolic process,GO:0005524//ATP binding;GO:0016874//ligase activity,-
80222,0,0,1,0,0,0,0,44,8,0,2,0,"TARS2;threonyl-tRNA synthetase 2, mitochondrial (putative)",GO:0005759//mitochondrial matrix,GO:0070159//mitochondrial threonyl-tRNA aminoacylation;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation,GO:0005524//ATP binding;GO:0004829//threonine-tRNA ligase activity,K01868//Vitamin B6 metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
80223,0,17,0,69,91,0,15,25,71,0,0,0,RAB11FIP1;RAB11 family interacting protein 1 (class I),GO:0055037//recycling endosome;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0030670//phagocytic vesicle membrane,GO:0015031//protein transport,-,K12484//Endocytosis
80224,0,0,29,0,13,0,0,0,32,0,0,0,NUBPL;nucleotide binding protein-like,GO:0005739//mitochondrion,GO:0032981//mitochondrial respiratory chain complex I assembly;GO:0070584//mitochondrion morphogenesis,"GO:0046872//metal ion binding;GO:0005524//ATP binding;GO:0051539//4 iron, 4 sulfur cluster binding",-
80227,0,0,1,0,6,0,0,0,29,0,9,0,PAAF1;proteasomal ATPase-associated factor 1,GO:0000502//proteasome complex,GO:0016032//viral process,GO:0005515//protein binding,-
80228,77,0,0,39,143,0,34,75,89,0,60,0,ORAI2;ORAI calcium release-activated calcium modulator 2,GO:0030426//growth cone;GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K16057//Calcium signaling pathway
80230,60,0,0,12,2,10,0,44,30,1,0,0,RUFY1;RUN and FYVE domain containing 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane,GO:0015031//protein transport;GO:0030100//regulation of endocytosis;GO:0006897//endocytosis,GO:0008289//lipid binding;GO:0008565//protein transporter activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K12482//Endocytosis
80231,0,0,0,0,0,0,0,0,5,0,18,1,CXorf21;chromosome X open reading frame 21,-,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
80232,0,5,2,85,267,7,31,1,76,0,0,0,WDR26;WD repeat domain 26,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
80233,0,33,31,6,13,0,43,1,19,0,21,0,C17orf70;chromosome 17 open reading frame 70,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0043240//Fanconi anaemia nuclear complex,GO:0006281//DNA repair,GO:0003677//DNA binding;GO:0005515//protein binding,K10993//Fanconi anemia pathway
80235,0,0,0,0,0,0,0,0,2,24,21,0,"PIGZ;phosphatidylinositol glycan anchor biosynthesis, class Z",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0097502//mannosylation;GO:0006506//GPI anchor biosynthetic process,"GO:0000026//alpha-1,2-mannosyltransferase activity;GO:0000030//mannosyltransferase activity",K08098//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
80237,0,0,0,23,0,6,0,101,18,3,19,0,ELL3;elongation factor RNA polymerase II-like 3,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0008023//transcription elongation factor complex,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000179//positive regulation of neural precursor cell proliferation;GO:0050769//positive regulation of neurogenesis;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0048863//stem cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0007283//spermatogenesis;GO:0010717//regulation of epithelial to mesenchymal transition;GO:0042795//snRNA transcription from RNA polymerase II promoter",GO:0035326//enhancer binding,-
80243,237,0,0,0,0,23,19,0,83,213,0,0,"PREX2;phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2",-,GO:0007186//G-protein coupled receptor signaling pathway;GO:0035556//intracellular signal transduction;GO:0048813//dendrite morphogenesis;GO:0032855//positive regulation of Rac GTPase activity;GO:0008344//adult locomotory behavior,GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0030675//Rac GTPase activator activity,K12365//Chemokine signaling pathway
80254,1,324,114,366,409,35,55,517,118,0,225,1,CEP63;centrosomal protein 63kDa,GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome;GO:0000922//spindle pole,GO:0042770//signal transduction in response to DNA damage;GO:0007067//mitotic nuclear division;GO:0007099//centriole replication;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000077//DNA damage checkpoint;GO:0051225//spindle assembly,GO:0005515//protein binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
80255,96,0,0,0,8,0,36,0,64,0,0,0,"SLC35F5;solute carrier family 35, member F5",GO:0016021//integral component of membrane,GO:0006810//transport,-,-
80256,0,0,0,0,1,0,0,59,5,0,0,0,"FAM214B;family with sequence similarity 214, member B",GO:0005634//nucleus,-,-,-
80258,0,0,0,0,0,90,22,0,60,0,0,0,EFHC2;EF-hand domain (C-terminal) containing 2,-,-,GO:0005509//calcium ion binding,-
80262,0,28,0,0,1,41,4,0,82,0,31,0,C16orf70;chromosome 16 open reading frame 70,-,-,GO:0005515//protein binding,-
80263,24,0,0,0,0,31,0,11,1,95,7,0,TRIM45;tripartite motif containing 45,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0060348//bone development,GO:0008270//zinc ion binding,-
80264,0,0,0,5,28,0,0,0,14,0,0,0,ZNF430;zinc finger protein 430,GO:0005634//nucleus,"GO:0021762//substantia nigra development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
80267,0,54,0,20,32,0,29,0,89,0,0,0,"EDEM3;ER degradation enhancer, mannosidase alpha-like 3",GO:0005788//endoplasmic reticulum lumen;GO:0005789//endoplasmic reticulum membrane,GO:0006516//glycoprotein catabolic process;GO:0043687//post-translational protein modification;GO:0006457//protein folding;GO:0006986//response to unfolded protein;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,"GO:0004569//glycoprotein endo-alpha-1,2-mannosidase activity;GO:0005509//calcium ion binding;GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity",K10086//Protein processing in endoplasmic reticulum
8027,0,2,0,5,66,0,0,46,29,0,1,0,STAM;signal transducing adaptor molecule (SH3 domain and ITAM motif) 1,GO:0005829//cytosol;GO:0031901//early endosome membrane,GO:0007165//signal transduction;GO:0061024//membrane organization;GO:0016197//endosomal transport;GO:0006886//intracellular protein transport;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0005070//SH3/SH2 adaptor activity,K04705//Endocytosis;Jak-STAT signaling pathway
80270,0,0,0,0,0,0,0,0,27,0,0,0,"HSD3B7;hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0055114//oxidation-reduction process,"GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity;GO:0047016//cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity",K12408//Metabolic pathways;Primary bile acid biosynthesis
80271,0,0,0,0,60,36,36,30,27,0,43,0,ITPKC;inositol-trisphosphate 3-kinase C,GO:0005829//cytosol;GO:0005634//nucleus,GO:0016310//phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process,"GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity",K00911//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Calcium signaling pathway
80273,0,0,0,33,35,21,0,0,0,0,0,0,"GRPEL1;GrpE-like 1, mitochondrial (E. coli)",GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0050790//regulation of catalytic activity;GO:0044267//cellular protein metabolic process;GO:0006457//protein folding;GO:0006626//protein targeting to mitochondrion,GO:0051082//unfolded protein binding;GO:0000774//adenyl-nucleotide exchange factor activity;GO:0042803//protein homodimerization activity;GO:0051087//chaperone binding,-
80274,18,0,0,0,0,0,18,0,2,84,0,186,"SCUBE1;signal peptide, CUB domain, EGF-like 1",GO:0019897//extrinsic component of plasma membrane;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0009897//external side of plasma membrane,GO:0006954//inflammatory response;GO:0051260//protein homooligomerization;GO:0007596//blood coagulation;GO:0045446//endothelial cell differentiation;GO:0007512//adult heart development;GO:0009791//post-embryonic development,GO:0005509//calcium ion binding;GO:0042802//identical protein binding;GO:0046982//protein heterodimerization activity,-
80279,65,1,0,2,1,0,0,58,1,0,0,0,CDK5RAP3;CDK5 regulatory subunit associated protein 3,GO:0016020//membrane,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0045664//regulation of neuron differentiation;GO:0071569//protein ufmylation;GO:0007420//brain development,GO:0019901//protein kinase binding;GO:0005515//protein binding,-
8028,0,0,0,11,5,44,19,0,40,0,0,251,"MLLT10;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
8029,65,0,0,4,0,18,7,10,168,220,0,1,CUBN;cubilin (intrinsic factor-cobalamin receptor),GO:0043202//lysosomal lumen;GO:0005765//lysosomal membrane;GO:0031232//extrinsic component of external side of plasma membrane;GO:0016324//apical plasma membrane;GO:0005905//coated pit;GO:0005794//Golgi apparatus;GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0030139//endocytic vesicle,GO:0001894//tissue homeostasis;GO:0042359//vitamin D metabolic process;GO:0009235//cobalamin metabolic process;GO:0042157//lipoprotein metabolic process;GO:0042953//lipoprotein transport;GO:0015889//cobalamin transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0006766//vitamin metabolic process;GO:0006898//receptor-mediated endocytosis;GO:0008202//steroid metabolic process;GO:0008203//cholesterol metabolic process,GO:0005215//transporter activity;GO:0004872//receptor activity;GO:0031419//cobalamin binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K14616//Vitamin digestion and absorption
80298,24,67,0,13,0,0,0,0,26,0,0,0,MTERF2;mitochondrial transcription termination factor 2,GO:0005759//mitochondrial matrix;GO:0042645//mitochondrial nucleoid,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0042803//protein homodimerization activity,-
8030,0,50,2,53,227,2,0,0,28,0,8,0,CCDC6;coiled-coil domain containing 6,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,GO:0005200//structural constituent of cytoskeleton;GO:0017124//SH3 domain binding;GO:0005515//protein binding,K09288//Thyroid cancer;Pathways in cancer
80301,1,0,0,0,0,0,14,0,45,0,0,0,"PLEKHO2;pleckstrin homology domain containing, family O member 2",-,-,-,-
80303,0,0,0,0,13,20,52,46,1,0,1,0,"EFHD1;EF-hand domain family, member D1",GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane,GO:0031175//neuron projection development,GO:0005509//calcium ion binding,-
80304,0,0,0,0,15,0,0,0,0,0,0,0,C2orf44;chromosome 2 open reading frame 44,-,-,-,-
80305,99,0,0,6,16,15,10,125,50,0,28,0,TRABD;TraB domain containing,-,-,-,-
80306,0,1,0,8,87,0,0,54,18,0,0,0,MED28;mediator complex subunit 28,GO:0016020//membrane;GO:0016592//mediator complex;GO:0030864//cortical actin cytoskeleton,"GO:0019827//stem cell maintenance;GO:0006355//regulation of transcription, DNA-templated;GO:0051151//negative regulation of smooth muscle cell differentiation;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003779//actin binding,-
80307,58,1,24,0,11,58,29,0,67,0,0,0,"FER1L4;fer-1-like family member 4, pseudogene (functional)",GO:0016021//integral component of membrane,-,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption
80308,0,0,0,0,2,0,0,0,0,0,0,0,FLAD1;flavin adenine dinucleotide synthetase 1,GO:0005759//mitochondrial matrix;GO:0005829//cytosol,GO:0006771//riboflavin metabolic process;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006747//FAD biosynthetic process;GO:0006766//vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process,GO:0005524//ATP binding;GO:0003919//FMN adenylyltransferase activity,K00953//Metabolic pathways;Riboflavin metabolism
80309,9,0,0,0,0,32,44,50,83,0,0,0,"SPHKAP;SPHK1 interactor, AKAP domain containing",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0030018//Z disc,-,GO:0005515//protein binding;GO:0051018//protein kinase A binding,-
8031,0,844,5,517,1840,31,1,0,15,0,37,285,NCOA4;nuclear receptor coactivator 4,GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0008584//male gonad development;GO:0009725//response to hormone",GO:0003713//transcription coactivator activity;GO:0050681//androgen receptor binding,K09289//Thyroid cancer;Pathways in cancer
80310,0,0,0,0,0,0,0,64,19,0,0,0,PDGFD;platelet derived growth factor D,GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane,GO:0071230//cellular response to amino acid stimulus;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0051781//positive regulation of cell division;GO:0007275//multicellular organismal development;GO:0050730//regulation of peptidyl-tyrosine phosphorylation,GO:0008083//growth factor activity;GO:0005161//platelet-derived growth factor receptor binding,K05450//Cytokine-cytokine receptor interaction;Melanoma;Regulation of actin cytoskeleton;Gap junction;Focal adhesion;Prostate cancer
80311,0,0,0,0,18,19,59,0,41,0,0,0,KLHL15;kelch-like family member 15,-,GO:0016567//protein ubiquitination,-,-
80312,272,0,0,26,39,12,37,51,43,0,1,0,TET1;tet methylcytosine dioxygenase 1,GO:0005634//nucleus,"GO:0090310//negative regulation of methylation-dependent chromatin silencing;GO:0006493//protein O-linked glycosylation;GO:0019827//stem cell maintenance;GO:0006351//transcription, DNA-templated;GO:0044030//regulation of DNA methylation;GO:0055114//oxidation-reduction process;GO:0016568//chromatin modification;GO:0080111//DNA demethylation;GO:0001826//inner cell mass cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0070579//methylcytosine dioxygenase activity;GO:0043566//structure-specific DNA binding;GO:0005506//iron ion binding;GO:0008270//zinc ion binding,-
80313,0,0,0,2,0,13,0,0,19,0,1,0,LRRC27;leucine rich repeat containing 27,-,-,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
80314,0,1,0,11,10,0,0,0,8,0,0,0,EPC1;enhancer of polycomb homolog 1 (Drosophila),GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm;GO:0032777//Piccolo NuA4 histone acetyltransferase complex,"GO:0043967//histone H4 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045814//negative regulation of gene expression, epigenetic;GO:0006325//chromatin organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043968//histone H2A acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006351//transcription, DNA-templated",GO:0004402//histone acetyltransferase activity,-
80315,0,0,0,19,55,24,10,86,11,0,1,0,CPEB4;cytoplasmic polyadenylation element binding protein 4,GO:0005783//endoplasmic reticulum;GO:0030425//dendrite;GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0043524//negative regulation of neuron apoptotic process;GO:0036294//cellular response to decreased oxygen levels;GO:0002931//response to ischemia;GO:0042149//cellular response to glucose starvation;GO:0071230//cellular response to amino acid stimulus,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K02602//Progesterone-mediated oocyte maturation;Dorso-ventral axis formation;Oocyte meiosis
80317,0,0,0,9,35,0,1,0,4,0,1,0,ZKSCAN3;zinc finger with KRAB and SCAN domains 3,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0010507//negative regulation of autophagy;GO:2000773//negative regulation of cellular senescence;GO:0007040//lysosome organization;GO:0006914//autophagy;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
80318,0,0,0,4,20,14,1,0,0,114,0,0,GKAP1;G kinase anchoring protein 1,GO:0005794//Golgi apparatus,GO:0007165//signal transduction,-,-
80320,0,0,0,0,0,0,0,0,26,0,0,0,SP6;Sp6 transcription factor,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0008284//positive regulation of cell proliferation;GO:0042481//regulation of odontogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
80321,54,77,0,22,46,0,0,0,1,0,6,1,CEP70;centrosomal protein 70kDa,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0031965//nuclear membrane;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K03956//Huntington's disease;Parkinson's disease;Oxidative phosphorylation;Alzheimer's disease;Metabolic pathways;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
80323,0,15,1,0,19,0,0,35,22,0,0,0,CCDC68;coiled-coil domain containing 68,-,-,-,-
80324,0,0,0,0,0,13,0,0,20,0,0,0,PUS1;pseudouridylate synthase 1,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0000790//nuclear chromatin;GO:0005667//transcription factor complex,GO:0031119//tRNA pseudouridine synthesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0044822//poly(A) RNA binding;GO:0004730//pseudouridylate synthase activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0009982//pseudouridine synthase activity,-
80325,0,0,1,0,0,1,0,66,0,0,0,0,ABTB1;ankyrin repeat and BTB (POZ) domain containing 1,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0006414//translational elongation,GO:0003746//translation elongation factor activity,-
80326,0,0,12,0,0,0,0,0,0,0,0,0,"WNT10A;wingless-type MMTV integration site family, member 10A",GO:0005578//proteinaceous extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0031069//hair follicle morphogenesis;GO:0045165//cell fate commitment;GO:0042476//odontogenesis;GO:0001942//hair follicle development;GO:0016055//Wnt signaling pathway;GO:0043586//tongue development;GO:0043588//skin development;GO:0030182//neuron differentiation;GO:0010628//positive regulation of gene expression;GO:0048730//epidermis morphogenesis;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0048733//sebaceous gland development;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0014033//neural crest cell differentiation,GO:0005109//frizzled binding,K01357//Melanogenesis;Basal cell carcinoma;HTLV-I infection;Wnt signaling pathway;Hedgehog signaling pathway;Pathways in cancer
80329,74,0,0,0,0,0,34,0,0,0,0,0,ULBP1;UL16 binding protein 1,GO:0005783//endoplasmic reticulum;GO:0046658//anchored component of plasma membrane;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0019882//antigen processing and presentation;GO:0030101//natural killer cell activation;GO:0042267//natural killer cell mediated cytotoxicity,GO:0046703//natural killer cell lectin-like receptor binding,K07986//Natural killer cell mediated cytotoxicity
80331,0,2,2,10,30,5,16,3,57,0,19,0,"DNAJC5;DnaJ (Hsp40) homolog, subfamily C, member 5",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0042470//melanosome;GO:0008021//synaptic vesicle;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0061202//clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane;GO:0005739//mitochondrion,GO:0043524//negative regulation of neuron apoptotic process;GO:0006887//exocytosis;GO:0008219//cell death;GO:0007268//synaptic transmission;GO:0016079//synaptic vesicle exocytosis;GO:0007269//neurotransmitter secretion;GO:0045055//regulated secretory pathway,GO:0043008//ATP-dependent protein binding;GO:0001948//glycoprotein binding,K09525//Protein processing in endoplasmic reticulum
80332,0,0,0,0,0,5,6,0,1,13,0,0,ADAM33;ADAM metallopeptidase domain 33,GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
80333,29,0,0,15,0,12,0,0,32,162,0,0,KCNIP4;Kv channel interacting protein 4,GO:0043025//neuronal cell body;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005509//calcium ion binding;GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,K13764//Phototransduction
80335,12,45,3,16,47,0,0,129,11,0,6,0,WDR82;WD repeat domain 82,GO:0048188//Set1C/COMPASS complex;GO:0000785//chromatin;GO:0035097//histone methyltransferase complex;GO:0072357//PTW/PP1 phosphatase complex,GO:0051568//histone H3-K4 methylation,GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003682//chromatin binding;GO:0005515//protein binding,K14962//mRNA surveillance pathway
80336,62,0,0,0,0,0,0,0,70,0,0,0,"PABPC1L;poly(A) binding protein, cytoplasmic 1-like",GO:0070062//extracellular vesicular exosome,GO:0006378//mRNA polyadenylation;GO:0001556//oocyte maturation,GO:0003723//RNA binding;GO:0000166//nucleotide binding,K13126//RNA transport;mRNA surveillance pathway;RNA degradation
80339,0,0,0,0,0,16,21,0,6,0,17,0,PNPLA3;patatin-like phospholipase domain containing 3,GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0019433//triglyceride catabolic process;GO:0019432//triglyceride biosynthetic process;GO:0036155//acylglycerol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0051265//diolein transacylation activity;GO:0051264//mono-olein transacylation activity;GO:0004623//phospholipase A2 activity;GO:0004806//triglyceride lipase activity,K13534//Glycerolipid metabolism;Metabolic pathways
8034,0,1,16,42,156,0,0,1,0,220,0,0,"SLC25A16;solute carrier family 25 (mitochondrial carrier), member 16",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0015939//pantothenate metabolic process;GO:0009108//coenzyme biosynthetic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0055085//transmembrane transport;GO:0006766//vitamin metabolic process;GO:0006810//transport,GO:0015297//antiporter activity,-
80341,78,0,0,0,0,11,23,0,40,1,0,0,"BPIFB2;BPI fold containing family B, member 2",GO:0070062//extracellular vesicular exosome,-,GO:0008289//lipid binding,-
80342,0,0,0,10,17,0,0,0,38,82,8,0,TRAF3IP3;TRAF3 interacting protein 3,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K06674//Cell cycle - yeast;K12478//Phagosome;Endocytosis;Tuberculosis;K15680//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Metabolic pathways
80343,1,0,0,0,0,0,68,0,16,2,27,333,SEL1L2;sel-1 suppressor of lin-12-like 2 (C. elegans),GO:0016021//integral component of membrane,-,-,-
80344,0,99,1,17,129,19,0,2,48,0,84,0,DCAF11;DDB1 and CUL4 associated factor 11,GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
80345,106,0,0,0,0,19,0,0,0,0,0,0,ZSCAN16;zinc finger and SCAN domain containing 16,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
80346,0,0,0,0,0,16,0,0,0,0,0,0,REEP4;receptor accessory protein 4,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005874//microtubule,GO:0007084//mitotic nuclear envelope reassembly;GO:0007067//mitotic nuclear division;GO:0006998//nuclear envelope organization,GO:0008017//microtubule binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
80347,0,0,0,2,0,9,0,0,54,0,3,0,COASY;CoA synthase,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0005741//mitochondrial outer membrane;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome,GO:0016310//phosphorylation;GO:0008219//cell death;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0015937//coenzyme A biosynthetic process;GO:0006766//vitamin metabolic process;GO:0015939//pantothenate metabolic process;GO:0009108//coenzyme biosynthetic process,GO:0004595//pantetheine-phosphate adenylyltransferase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004140//dephospho-CoA kinase activity,K02318//Pantothenate and CoA biosynthesis;Metabolic pathways
80349,0,27,0,0,6,2,31,0,0,0,13,0,WDR61;WD repeat domain 61,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0055087//Ski complex;GO:0005730//nucleolus;GO:0016593//Cdc73/Paf1 complex;GO:0035327//transcriptionally active chromatin,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation;GO:2001162//positive regulation of histone H3-K79 methylation;GO:0016055//Wnt signaling pathway;GO:0080182//histone H3-K4 trimethylation;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter",GO:0005515//protein binding,K12602//RNA degradation
80350,0,0,0,0,0,21,0,0,35,0,10,0,"LPAL2;lipoprotein, Lp(a)-like 2, pseudogene",GO:0005576//extracellular region,-,-,-
80351,151,2,0,29,110,39,0,53,57,0,0,0,"TNKS2;tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005635//nuclear envelope;GO:0000242//pericentriolar material;GO:0000784//nuclear chromosome, telomeric region;GO:0000139//Golgi membrane","GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0016055//Wnt signaling pathway;GO:0006471//protein ADP-ribosylation;GO:0040014//regulation of multicellular organism growth;GO:0070198//protein localization to chromosome, telomeric region;GO:0035264//multicellular organism growth;GO:0070213//protein auto-ADP-ribosylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0000209//protein polyubiquitination",GO:0019899//enzyme binding;GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
80352,0,1,42,0,39,0,0,0,0,0,0,0,RNF39;ring finger protein 39,GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding,-
8036,0,1,0,6,76,12,3,0,21,0,0,0,SHOC2;soc-2 suppressor of clear homolog (C. elegans),GO:0005730//nucleolus;GO:0000164//protein phosphatase type 1 complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007265//Ras protein signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0050790//regulation of catalytic activity;GO:0046579//positive regulation of Ras protein signal transduction,GO:0019903//protein phosphatase binding;GO:0019888//protein phosphatase regulator activity,K01768//Meiosis - yeast;Purine metabolism;K12796//NOD-like receptor signaling pathway
8038,0,0,6,0,0,22,0,0,23,0,0,0,ADAM12;ADAM metallopeptidase domain 12,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007520//myoblast fusion;GO:0006508//proteolysis;GO:0007155//cell adhesion,GO:0004222//metalloendopeptidase activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
80380,0,0,0,0,0,12,0,0,16,0,6,0,PDCD1LG2;programmed cell death 1 ligand 2,GO:0012505//endomembrane system;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042130//negative regulation of T cell proliferation;GO:0006955//immune response;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation,-,K06708//Cell adhesion molecules (CAMs)
80381,0,0,0,0,6,0,0,2,18,0,4,0,CD276;CD276 molecule,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0006955//immune response;GO:0008283//cell proliferation;GO:0042130//negative regulation of T cell proliferation;GO:0050728//negative regulation of inflammatory response;GO:0042110//T cell activation;GO:0045085//negative regulation of interleukin-2 biosynthetic process;GO:0045078//positive regulation of interferon-gamma biosynthetic process;GO:0050776//regulation of immune response;GO:0042102//positive regulation of T cell proliferation;GO:0045077//negative regulation of interferon-gamma biosynthetic process;GO:0045669//positive regulation of osteoblast differentiation;GO:0030501//positive regulation of bone mineralization,GO:0005515//protein binding;GO:0005102//receptor binding,K06746//Cell adhesion molecules (CAMs)
8045,38,0,0,0,0,17,0,0,13,0,12,0,RASSF7;Ras association (RalGDS/AF-6) domain family (N-terminal) member 7,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,GO:0007165//signal transduction;GO:0006915//apoptotic process,-,-
8048,0,0,0,0,0,0,0,0,7,0,17,0,CSRP3;cysteine and glycine-rich protein 3 (cardiac LIM protein),GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0030018//Z disc,GO:0055003//cardiac myofibril assembly;GO:0002026//regulation of the force of heart contraction;GO:0006874//cellular calcium ion homeostasis;GO:0060048//cardiac muscle contraction;GO:0033365//protein localization to organelle;GO:0035995//detection of muscle stretch;GO:0003300//cardiac muscle hypertrophy;GO:0048738//cardiac muscle tissue development;GO:0007519//skeletal muscle tissue development,GO:0008307//structural constituent of muscle;GO:0031433//telethonin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0042805//actinin binding,-
805,0,64,1,87,220,0,8,0,0,0,0,0,"CALM2;calmodulin 2 (phosphorylase kinase, delta)",-,-,-,K02183//Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Oocyte meiosis;Vascular smooth muscle contraction;Pertussis;Tuberculosis;Alcoholism;Long-term potentiation;Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system;Phototransduction;Insulin signaling pathway;Gastric acid secretion;Glioma;Melanogenesis;Alzheimer's disease;Neurotrophin signaling pathway;Calcium signaling pathway;Olfactory transduction;Salivary secretion
8050,0,72,0,56,232,0,6,0,50,56,174,1,"PDHX;pyruvate dehydrogenase complex, component X",GO:0005759//mitochondrial matrix,GO:0010510//regulation of acetyl-CoA biosynthetic process from pyruvate;GO:0044237//cellular metabolic process;GO:0006090//pyruvate metabolic process;GO:0044281//small molecule metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K13997//Metabolic pathways
8065,0,175,41,32,160,10,58,405,33,0,140,0,CUL5;cullin 5,GO:0005634//nucleus;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0005886//plasma membrane,GO:0016567//protein ubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0070588//calcium ion transmembrane transport;GO:0051480//cytosolic calcium ion homeostasis;GO:0008283//cell proliferation;GO:0007050//cell cycle arrest;GO:0006970//response to osmotic stress;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle,GO:0046982//protein heterodimerization activity;GO:0031625//ubiquitin protein ligase binding;GO:0005262//calcium channel activity;GO:0005515//protein binding;GO:0004872//receptor activity,K10612//Ubiquitin mediated proteolysis
80700,0,0,1,0,33,0,0,1,1,0,5,0,UBXN6;UBX domain protein 6,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,-,GO:0005515//protein binding,K14011//Protein processing in endoplasmic reticulum
80704,0,0,0,0,0,0,14,40,14,0,0,0,"SLC19A3;solute carrier family 19 (thiamine transporter), member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0042723//thiamine-containing compound metabolic process;GO:0006766//vitamin metabolic process;GO:0071934//thiamine transmembrane transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process,GO:0015403//thiamine uptake transmembrane transporter activity,K14610//Vitamin digestion and absorption
80705,0,0,0,8,7,32,0,0,47,70,0,0,"TSGA10;testis specific, 10",GO:0043005//neuron projection;GO:0031514//motile cilium;GO:0031965//nuclear membrane;GO:0005737//cytoplasm,GO:0030031//cell projection assembly;GO:0007283//spermatogenesis,-,-
80709,109,0,0,0,9,65,56,34,42,0,3,0,AKNA;AT-hook transcription factor,GO:0005634//nucleus;GO:0016020//membrane,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites
80712,0,0,0,0,0,13,0,0,28,0,0,0,ESX1;ESX homeobox 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060713//labyrinthine layer morphogenesis;GO:0051726//regulation of cell cycle;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060716//labyrinthine layer blood vessel development",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0043565//sequence-specific DNA binding,-
80714,0,0,0,0,0,0,0,0,23,0,2,0,PBX4;pre-B-cell leukemia homeobox 4,GO:0001741//XY body;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
80723,0,0,0,0,0,0,39,0,0,0,0,0,"SLC35G2;solute carrier family 35, member G2",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus,-,-,-
80724,61,0,0,0,8,5,0,0,68,0,0,0,"ACAD10;acyl-CoA dehydrogenase family, member 10",GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,"GO:0050660//flavin adenine dinucleotide binding;GO:0003995//acyl-CoA dehydrogenase activity;GO:0016787//hydrolase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups",-
80725,2,0,0,0,4,20,0,102,62,0,19,0,SRCIN1;SRC kinase signaling inhibitor 1,GO:0005925//focal adhesion;GO:0030424//axon;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0045202//synapse;GO:0030425//dendrite;GO:0045211//postsynaptic membrane,GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0061001//regulation of dendritic spine morphogenesis;GO:0006887//exocytosis;GO:0030334//regulation of cell migration;GO:0034446//substrate adhesion-dependent cell spreading;GO:0061099//negative regulation of protein tyrosine kinase activity,GO:0005515//protein binding;GO:0019901//protein kinase binding,-
80726,0,0,0,0,0,0,0,26,4,0,0,0,KIAA1683;KIAA1683,GO:0005739//mitochondrion;GO:0005634//nucleus,-,-,-
80727,231,0,0,0,0,40,0,0,53,0,0,0,TTYH3;tweety family member 3,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0034707//chloride channel complex,GO:1902476//chloride transmembrane transport;GO:0034220//ion transmembrane transport;GO:0006821//chloride transport;GO:0055085//transmembrane transport,GO:0005254//chloride channel activity;GO:0005229//intracellular calcium activated chloride channel activity,-
80728,86,0,0,0,0,11,0,0,38,6,17,1,ARHGAP39;Rho GTPase activating protein 39,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005829//cytosol,GO:0007411//axon guidance;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,-,K01464//Drug metabolism - other enzymes;Pyrimidine metabolism;Pantothenate and CoA biosynthesis;Metabolic pathways;beta-Alanine metabolism;K07526//Axon guidance
8073,2,29,0,105,265,0,0,35,34,0,20,0,"PTP4A2;protein tyrosine phosphatase type IVA, member 2",GO:0005737//cytoplasm;GO:0005769//early endosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004727//prenylated protein tyrosine phosphatase activity,-
80731,0,0,1,0,0,35,1,0,58,0,10,0,"THSD7B;thrombospondin, type I, domain containing 7B",GO:0016021//integral component of membrane,-,-,-
80739,0,0,0,0,0,0,0,0,1,0,0,0,C6orf25;chromosome 6 open reading frame 25,GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0007596//blood coagulation;GO:0035855//megakaryocyte development;GO:0030220//platelet formation;GO:0007229//integrin-mediated signaling pathway,GO:0008201//heparin binding,K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
8074,0,0,0,0,0,0,0,0,13,0,0,0,FGF23;fibroblast growth factor 23,GO:0005615//extracellular space;GO:0005576//extracellular region,"GO:0007173//epidermal growth factor receptor signaling pathway;GO:0055062//phosphate ion homeostasis;GO:0030154//cell differentiation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0010966//regulation of phosphate transport;GO:0008286//insulin receptor signaling pathway;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045668//negative regulation of osteoblast differentiation;GO:0046888//negative regulation of hormone secretion;GO:0006796//phosphate-containing compound metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030502//negative regulation of bone mineralization;GO:0045087//innate immune response;GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0030643//cellular phosphate ion homeostasis;GO:0048015//phosphatidylinositol-mediated signaling;GO:0010980//positive regulation of vitamin D 24-hydroxylase activity;GO:0042369//vitamin D catabolic process",GO:0008083//growth factor activity;GO:0005105//type 1 fibroblast growth factor receptor binding,K04358//Melanoma;Regulation of actin cytoskeleton;MAPK signaling pathway;Pathways in cancer
80740,0,0,0,0,0,0,0,0,0,0,1,0,"LY6G6C;lymphocyte antigen 6 complex, locus G6C",GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,-,-,-
80742,2,0,0,0,0,0,0,0,0,0,0,0,PRR3;proline rich 3,-,-,GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
80745,0,0,0,6,16,0,0,0,1,0,24,0,THUMPD2;THUMP domain containing 2,-,GO:0032259//methylation,GO:0003723//RNA binding;GO:0008168//methyltransferase activity,-
80746,91,0,0,0,14,0,37,36,3,0,15,0,TSEN2;TSEN2 tRNA splicing endonuclease subunit,GO:0005730//nucleolus;GO:0000214//tRNA-intron endonuclease complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus,"GO:0006388//tRNA splicing, via endonucleolytic cleavage and ligation;GO:0006397//mRNA processing;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic",GO:0016829//lyase activity;GO:0000213//tRNA-intron endonuclease activity;GO:0003676//nucleic acid binding,-
80757,0,0,0,0,0,0,0,0,18,0,0,0,TMEM121;transmembrane protein 121,GO:0016021//integral component of membrane,-,-,-
80758,0,0,0,0,0,0,0,0,9,0,0,0,PRR7;proline rich 7 (synaptic),GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane,-,-,-
80759,0,1,0,0,0,0,0,0,0,0,0,0,KHDC1;KH homology domain containing 1,GO:0016021//integral component of membrane,-,GO:0003723//RNA binding,-
80760,0,0,0,0,0,0,0,0,67,235,0,407,"ITIH5;inter-alpha-trypsin inhibitor heavy chain family, member 5",GO:0005576//extracellular region,GO:0030212//hyaluronan metabolic process;GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K05316//MAPK signaling pathway
80761,0,0,0,0,0,2,18,0,10,0,0,0,UPK3B;uroplakin 3B,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0010629//negative regulation of gene expression,-,K06058//Notch signaling pathway
80762,63,34,0,24,74,0,3,0,23,0,0,0,NDFIP1;Nedd4 family interacting protein 1,GO:0010008//endosome membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005576//extracellular region;GO:0048471//perinuclear region of cytoplasm;GO:0005938//cell cortex,GO:0048294//negative regulation of isotype switching to IgE isotypes;GO:0045732//positive regulation of protein catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0051224//negative regulation of protein transport;GO:0010629//negative regulation of gene expression;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0002761//regulation of myeloid leukocyte differentiation;GO:0045619//regulation of lymphocyte differentiation;GO:0007165//signal transduction;GO:0031398//positive regulation of protein ubiquitination;GO:0032713//negative regulation of interleukin-4 production;GO:0050728//negative regulation of inflammatory response;GO:0032410//negative regulation of transporter activity;GO:0002829//negative regulation of type 2 immune response;GO:0042130//negative regulation of T cell proliferation,GO:0050699//WW domain binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,-
80763,0,0,0,0,0,13,0,0,0,0,0,0,SPX;spexin hormone,GO:0030133//transport vesicle;GO:0005615//extracellular space,GO:0044539//long-chain fatty acid import;GO:0032099//negative regulation of appetite;GO:0035814//negative regulation of renal sodium excretion;GO:0051930//regulation of sensory perception of pain;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010459//negative regulation of heart rate;GO:0003084//positive regulation of systemic arterial blood pressure,GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity,-
80764,0,0,46,0,0,0,0,0,11,220,53,1,THAP7;THAP domain containing 7,GO:0005694//chromosome;GO:0016607//nuclear speck,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0047485//protein N-terminus binding;GO:0070742//C2H2 zinc finger domain binding;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
80765,0,0,0,0,0,0,0,0,9,0,0,0,STARD5;StAR-related lipid transfer (START) domain containing 5,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006869//lipid transport;GO:0006700//C21-steroid hormone biosynthetic process;GO:0008202//steroid metabolic process,GO:0008289//lipid binding,-
80772,2,0,0,0,0,0,28,47,0,0,2,0,CPTP;ceramide-1-phosphate transfer protein,GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005640//nuclear outer membrane,GO:0046836//glycolipid transport;GO:1902389//ceramide 1-phosphate transport,GO:0005543//phospholipid binding;GO:1902387//ceramide 1-phosphate binding;GO:0051861//glycolipid binding;GO:1902388//ceramide 1-phosphate transporter activity;GO:0005548//phospholipid transporter activity,-
80774,0,69,64,105,181,0,21,180,45,0,265,0,LIMD2;LIM domain containing 2,-,-,GO:0008270//zinc ion binding,-
80775,0,0,0,0,6,0,58,0,0,0,0,0,TMEM177;transmembrane protein 177,GO:0016021//integral component of membrane,-,-,-
80776,0,17,0,0,10,20,7,0,0,0,6,0,B9D2;B9 protein domain 2,GO:0005829//cytosol;GO:0036064//ciliary basal body;GO:0016020//membrane;GO:0005634//nucleus;GO:0036038//TCTN-B9D complex;GO:0005813//centrosome,GO:0000278//mitotic cell cycle;GO:0042384//cilium assembly,GO:0005515//protein binding;GO:0043015//gamma-tubulin binding,-
80777,0,18,0,23,50,2,0,0,12,0,0,0,CYB5B;cytochrome b5 type B (outer mitochondrial membrane),GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0055114//oxidation-reduction process,GO:0020037//heme binding;GO:0046872//metal ion binding,K10595//Ubiquitin mediated proteolysis;K10226//Biosynthesis of unsaturated fatty acids;alpha-Linolenic acid metabolism;PPAR signaling pathway
80778,0,0,0,0,0,0,0,0,39,0,0,0,ZNF34;zinc finger protein 34,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
8078,0,1,0,7,69,0,63,0,49,0,0,0,USP5;ubiquitin specific peptidase 5 (isopeptidase T),GO:0005764//lysosome,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0071108//protein K48-linked deubiquitination;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0008270//zinc ion binding;GO:0004221//ubiquitin thiolesterase activity;GO:0008242//omega peptidase activity,-
80781,99,128,0,13,16,1,30,50,48,111,34,0,"COL18A1;collagen, type XVIII, alpha 1",GO:0005788//endoplasmic reticulum lumen;GO:0031012//extracellular matrix;GO:0005581//collagen trimer;GO:0005615//extracellular space;GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0030574//collagen catabolic process;GO:0051599//response to hydrostatic pressure;GO:0030335//positive regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0007155//cell adhesion;GO:0009887//organ morphogenesis;GO:0030198//extracellular matrix organization;GO:0042493//response to drug;GO:0008284//positive regulation of cell proliferation;GO:0022617//extracellular matrix disassembly;GO:0007601//visual perception;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0001525//angiogenesis;GO:0001886//endothelial cell morphogenesis,GO:0005198//structural molecule activity;GO:0042802//identical protein binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K06823//Protein digestion and absorption
80789,0,15,0,0,0,0,0,68,0,280,0,0,INTS5;integrator complex subunit 5,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0032039//integrator complex,GO:0016180//snRNA processing,GO:0005515//protein binding,-
8079,58,58,2,24,57,19,0,2,31,44,0,0,MLF2;myeloid leukemia factor 2,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006952//defense response,GO:0005515//protein binding,K15622//Transcriptional misregulation in cancer
80790,0,8,0,0,79,0,18,53,63,0,1,0,CMIP;c-Maf inducing protein,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005515//protein binding,-
808,0,47,1,6,188,22,0,1,29,0,0,0,"CALM3;calmodulin 3 (phosphorylase kinase, delta)",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0031982//vesicle;GO:0030426//growth cone;GO:0005813//centrosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0000922//spindle pole;GO:0005876//spindle microtubule;GO:0005634//nucleus;GO:0034704//calcium channel complex;GO:0030017//sarcomere;GO:0005829//cytosol,"GO:0007186//G-protein coupled receptor signaling pathway;GO:0051343//positive regulation of cyclic-nucleotide phosphodiesterase activity;GO:0007202//activation of phospholipase C activity;GO:0007603//phototransduction, visible light;GO:0007190//activation of adenylate cyclase activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0032516//positive regulation of phosphoprotein phosphatase activity;GO:0044281//small molecule metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0061024//membrane organization;GO:0007268//synaptic transmission;GO:0002027//regulation of heart rate;GO:0005980//glycogen catabolic process;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0031954//positive regulation of protein autophosphorylation;GO:0007165//signal transduction;GO:0005513//detection of calcium ion;GO:0021762//substantia nigra development;GO:0032465//regulation of cytokinesis;GO:0006006//glucose metabolic process;GO:0001975//response to amphetamine;GO:0010801//negative regulation of peptidyl-threonine phosphorylation;GO:0005975//carbohydrate metabolic process;GO:0046209//nitric oxide metabolic process;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0035307//positive regulation of protein dephosphorylation;GO:0055117//regulation of cardiac muscle contraction;GO:1901841//regulation of high voltage-gated calcium channel activity;GO:0045087//innate immune response;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0002576//platelet degranulation;GO:0006936//muscle contraction;GO:0051592//response to calcium ion;GO:0016056//rhodopsin mediated signaling pathway;GO:0051412//response to corticosterone;GO:0007596//blood coagulation;GO:0050999//regulation of nitric-oxide synthase activity;GO:0030168//platelet activation;GO:0007173//epidermal growth factor receptor signaling pathway",GO:0044325//ion channel binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0031996//thioesterase binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0008179//adenylate cyclase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0030235//nitric-oxide synthase regulator activity;GO:0072542//protein phosphatase activator activity;GO:0005515//protein binding;GO:0031997//N-terminal myristoylation domain binding;GO:0019901//protein kinase binding;GO:0031432//titin binding;GO:0019904//protein domain specific binding;GO:0050998//nitric-oxide synthase binding;GO:0031800//type 3 metabotropic glutamate receptor binding;GO:0043274//phospholipase binding,K02183//Long-term potentiation;Pertussis;Tuberculosis;Alcoholism;Phototransduction;Insulin signaling pathway;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Plant-pathogen interaction;Phototransduction - fly;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Melanogenesis;Gastric acid secretion;Glioma;Alzheimer's disease;Neurotrophin signaling pathway
80816,0,0,0,0,0,31,0,0,27,126,9,0,ASXL3;additional sex combs like transcriptional regulator 3,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
80817,0,1,21,7,31,0,0,127,77,0,0,0,CEP44;centrosomal protein 44kDa,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000922//spindle pole;GO:0030496//midbody,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
80818,0,0,0,17,124,20,26,44,59,0,20,0,ZNF436;zinc finger protein 436,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,-
8082,14,0,0,12,1,0,0,0,1,0,0,0,SSPN;sarcospan,GO:0030133//transport vesicle;GO:0005887//integral component of plasma membrane;GO:0042383//sarcolemma;GO:0016010//dystrophin-associated glycoprotein complex;GO:0030054//cell junction;GO:0045211//postsynaptic membrane,GO:0007155//cell adhesion;GO:0006936//muscle contraction,-,-
80820,1,0,0,0,0,15,41,0,54,0,0,0,EEPD1;endonuclease/exonuclease/phosphatase family domain containing 1,-,GO:0006281//DNA repair,GO:0003677//DNA binding,K10260//Ubiquitin mediated proteolysis
80821,0,0,0,0,0,8,20,29,95,0,17,0,DDHD1;DDHD domain containing 1,GO:0005737//cytoplasm,GO:0016042//lipid catabolic process;GO:0008219//cell death,GO:0046872//metal ion binding;GO:0016787//hydrolase activity,-
80823,29,0,0,2,10,32,0,0,27,0,0,0,"BHLHB9;basic helix-loop-helix domain containing, class B, 9",GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0007611//learning or memory;GO:0051965//positive regulation of synapse assembly;GO:0050769//positive regulation of neurogenesis;GO:0043524//negative regulation of neuron apoptotic process,GO:0042803//protein homodimerization activity,-
80824,0,97,2,94,177,13,19,0,32,0,43,0,DUSP16;dual specificity phosphatase 16,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005730//nucleolus,"GO:0045209//MAPK phosphatase export from nucleus, leptomycin B sensitive;GO:0045204//MAPK export from nucleus;GO:0000188//inactivation of MAPK activity;GO:0016311//dephosphorylation;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation",GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0017017//MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004721//phosphoprotein phosphatase activity,K04459//Serotonergic synapse;Transcriptional misregulation in cancer;MAPK signaling pathway
80829,48,72,2,24,106,12,27,0,80,116,0,0,ZFP91;ZFP91 zinc finger protein,GO:0005634//nucleus,GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0070534//protein K63-linked ubiquitination,GO:0003676//nucleic acid binding;GO:0004842//ubiquitin-protein transferase activity;GO:0046872//metal ion binding;GO:0016874//ligase activity,-
80830,33,0,1,28,41,41,54,0,46,115,36,0,"APOL6;apolipoprotein L, 6",GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0006869//lipid transport;GO:0042157//lipoprotein metabolic process,GO:0008289//lipid binding,K14480//African trypanosomiasis
80831,1,0,0,0,0,0,0,0,0,0,0,0,"APOL5;apolipoprotein L, 5",GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0042157//lipoprotein metabolic process;GO:0006629//lipid metabolic process;GO:0006869//lipid transport,GO:0008289//lipid binding;GO:0008035//high-density lipoprotein particle binding,K14480//African trypanosomiasis
80832,0,0,0,7,13,10,0,89,29,0,0,0,"APOL4;apolipoprotein L, 4",GO:0005615//extracellular space,GO:0006629//lipid metabolic process;GO:0042157//lipoprotein metabolic process;GO:0006869//lipid transport,GO:0008289//lipid binding,K14480//African trypanosomiasis
80833,134,18,0,0,12,14,0,0,5,0,0,0,"APOL3;apolipoprotein L, 3",GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0006869//lipid transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0042157//lipoprotein metabolic process;GO:0006954//inflammatory response,GO:0004871//signal transducer activity;GO:0008289//lipid binding;GO:0005319//lipid transporter activity,K14480//African trypanosomiasis
80834,0,0,0,0,0,0,30,50,10,0,0,0,"TAS1R2;taste receptor, type 1, member 2",GO:0043235//receptor complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050916//sensory perception of sweet taste;GO:0032467//positive regulation of cytokinesis;GO:0001582//detection of chemical stimulus involved in sensory perception of sweet taste;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008527//taste receptor activity;GO:0033041//sweet taste receptor activity;GO:0046982//protein heterodimerization activity,K04625//Carbohydrate digestion and absorption;Taste transduction
80835,0,0,50,0,0,0,0,0,45,0,0,0,"TAS1R1;taste receptor, type 1, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050912//detection of chemical stimulus involved in sensory perception of taste;GO:0050917//sensory perception of umami taste,GO:0046982//protein heterodimerization activity;GO:0008527//taste receptor activity,K04624//Taste transduction
8085,85,0,45,19,55,40,76,49,117,88,33,0,KMT2D;lysine (K)-specific methyltransferase 2D,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,"GO:0051568//histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0006342//chromatin silencing;GO:0043627//response to estrogen;GO:0048477//oogenesis;GO:0001555//oocyte growth;GO:0033148//positive regulation of intracellular estrogen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0006355//regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,K09187//Lysine degradation
80851,0,1,1,1,5,0,28,0,23,0,0,0,SH3BP5L;SH3-binding domain protein 5-like,-,-,-,-
80852,0,0,0,0,3,36,35,5,34,3,6,0,GRIP2;glutamate receptor interacting protein 2,GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0007268//synaptic transmission,-,K06092//Tight junction
80853,0,31,1,21,80,0,31,0,83,579,2,0,KDM7A;lysine (K)-specific demethylase 7A,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0055114//oxidation-reduction process;GO:0006351//transcription, DNA-templated;GO:0070544//histone H3-K36 demethylation;GO:0030901//midbrain development;GO:0035574//histone H4-K20 demethylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071557//histone H3-K27 demethylation;GO:0033169//histone H3-K9 demethylation","GO:0035064//methylated histone binding;GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0005506//iron ion binding;GO:0035575//histone demethylase activity (H4-K20 specific);GO:0051864//histone demethylase activity (H3-K36 specific);GO:0032454//histone demethylase activity (H3-K9 specific);GO:0008270//zinc ion binding;GO:0071558//histone demethylase activity (H3-K27 specific)",-
80854,0,306,3,181,828,0,0,88,63,0,0,3,SETD7;SET domain containing (lysine methyltransferase) 7,GO:0005634//nucleus;GO:0005694//chromosome,"GO:0034968//histone lysine methylation;GO:0006351//transcription, DNA-templated;GO:0018027//peptidyl-lysine dimethylation;GO:0018026//peptidyl-lysine monomethylation;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0002039//p53 binding;GO:0005515//protein binding;GO:0016279//protein-lysine N-methyltransferase activity;GO:0018024//histone-lysine N-methyltransferase activity,K11431//Lysine degradation
80856,102,0,0,0,56,18,15,0,8,0,0,0,KIAA1715;KIAA1715,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0032330//regulation of chondrocyte differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0007596//blood coagulation;GO:0042733//embryonic digit morphogenesis;GO:0060173//limb development,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
8086,8,0,0,5,6,0,0,0,0,1,0,0,"AAAS;achalasia, adrenocortical insufficiency, alacrimia",GO:0005643//nuclear pore;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0016020//membrane,GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process;GO:0051028//mRNA transport;GO:0006913//nucleocytoplasmic transport;GO:0010827//regulation of glucose transport;GO:0046822//regulation of nucleocytoplasmic transport;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0009566//fertilization;GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0015031//protein transport;GO:0019221//cytokine-mediated signaling pathway;GO:0007612//learning,-,K14320//RNA transport
80868,0,33,4,11,0,3,0,17,12,0,10,0,HCG4B;HLA complex group 4B (non-protein coding),-,-,-,K06751//Type I diabetes mellitus;Autoimmune thyroid disease;Phagosome;HTLV-I infection;Endocytosis;Epstein-Barr virus infection;Antigen processing and presentation;Allograft rejection;Graft-versus-host disease;Viral myocarditis;Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs);Herpes simplex infection
8087,0,43,1,73,263,23,16,0,30,0,0,2,"FXR1;fragile X mental retardation, autosomal homolog 1",GO:0005737//cytoplasm;GO:0005844//polysome;GO:0005730//nucleolus;GO:0043034//costamere;GO:0016020//membrane,GO:0006915//apoptotic process;GO:0030154//cell differentiation;GO:0017148//negative regulation of translation;GO:0007517//muscle organ development,GO:0044822//poly(A) RNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0002151//G-quadruplex RNA binding;GO:0003723//RNA binding,K15516//RNA transport
8089,0,0,1,17,12,0,0,0,16,0,0,0,YEATS4;YEATS domain containing 4,GO:0035267//NuA4 histone acetyltransferase complex;GO:0005654//nucleoplasm;GO:0016363//nuclear matrix,"GO:0007067//mitotic nuclear division;GO:0006325//chromatin organization;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043967//histone H4 acetylation",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0008022//protein C-terminus binding,-
80895,0,0,0,0,0,0,0,19,0,0,0,0,ILKAP;integrin-linked kinase-associated serine/threonine phosphatase,GO:0005737//cytoplasm,GO:0006470//protein dephosphorylation;GO:0033262//regulation of nuclear cell cycle DNA replication,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,K04457//MAPK signaling pathway
80896,1,0,0,0,11,0,4,94,0,0,11,328,NPL;N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase),GO:0005737//cytoplasm,GO:0019262//N-acetylneuraminate catabolic process;GO:0005975//carbohydrate metabolic process,GO:0008747//N-acetylneuraminate lyase activity,K01639//Amino sugar and nucleotide sugar metabolism
8091,0,0,0,0,0,23,0,0,18,23,0,0,HMGA2;high mobility group AT-hook 2,GO:0035985//senescence-associated heterochromatin focus;GO:0071141//SMAD protein complex;GO:0032993//protein-DNA complex;GO:0000228//nuclear chromosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:2000685//positive regulation of cellular response to X-ray;GO:0030325//adrenal gland development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0002062//chondrocyte differentiation;GO:0035987//endodermal cell differentiation;GO:0031052//chromosome breakage;GO:0021983//pituitary gland development;GO:0001837//epithelial to mesenchymal transition;GO:0042769//DNA damage response, detection of DNA damage;GO:0048762//mesenchymal cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0003131//mesodermal-endodermal cell signaling;GO:0043922//negative regulation by host of viral transcription;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0043065//positive regulation of apoptotic process;GO:0045869//negative regulation of single stranded viral RNA replication via double stranded DNA intermediate;GO:0010564//regulation of cell cycle process;GO:0031507//heterochromatin assembly;GO:2001033//negative regulation of double-strand break repair via nonhomologous end joining;GO:0045892//negative regulation of transcription, DNA-templated;GO:2001038//regulation of cellular response to drug;GO:0007165//signal transduction;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0007067//mitotic nuclear division;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0043392//negative regulation of DNA binding;GO:0035986//senescence-associated heterochromatin focus assembly;GO:0009615//response to virus;GO:0060123//regulation of growth hormone secretion;GO:0043066//negative regulation of apoptotic process;GO:0010628//positive regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:2000648//positive regulation of stem cell proliferation;GO:0021846//cell proliferation in forebrain;GO:0048333//mesodermal cell differentiation;GO:0035978//histone H2A-S139 phosphorylation;GO:0071158//positive regulation of cell cycle arrest;GO:2001022//positive regulation of response to DNA damage stimulus;GO:2000036//regulation of stem cell maintenance;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:2000774//positive regulation of cellular senescence;GO:0090402//oncogene-induced cell senescence;GO:0048863//stem cell differentiation;GO:0000737//DNA catabolic process, endonucleolytic;GO:0046426//negative regulation of JAK-STAT cascade;GO:0060613//fat pad development;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0035019//somatic stem cell maintenance;GO:0035988//chondrocyte proliferation;GO:0030261//chromosome condensation;GO:0006284//base-excision repair;GO:0048712//negative regulation of astrocyte differentiation;GO:0040018//positive regulation of multicellular organism growth","GO:0035501//MH1 domain binding;GO:0000975//regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004677//DNA-dependent protein kinase activity;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0070742//C2H2 zinc finger domain binding;GO:0031492//nucleosomal DNA binding;GO:0046332//SMAD binding;GO:0008134//transcription factor binding;GO:0035497//cAMP response element binding;GO:0005515//protein binding;GO:0035500//MH2 domain binding;GO:0000988//protein binding transcription factor activity;GO:0003677//DNA binding;GO:0003680//AT DNA binding;GO:0001047//core promoter binding;GO:0051575//5'-deoxyribose-5-phosphate lyase activity;GO:0008301//DNA binding, bending;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0019899//enzyme binding",K09283//Transcriptional misregulation in cancer
8092,0,0,0,0,0,0,0,0,0,0,24,0,ALX1;ALX homeobox 1,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0060021//palate development;GO:0007275//multicellular organismal development;GO:0048704//embryonic skeletal system morphogenesis;GO:0001502//cartilage condensation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007420//brain development;GO:0006366//transcription from RNA polymerase II promoter;GO:0014031//mesenchymal cell development;GO:0001843//neural tube closure;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009952//anterior/posterior pattern specification;GO:0030326//embryonic limb morphogenesis",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
80975,0,0,0,0,0,0,0,0,36,0,0,0,"TMPRSS5;transmembrane protease, serine 5",GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006508//proteolysis;GO:0006898//receptor-mediated endocytosis,GO:0004252//serine-type endopeptidase activity;GO:0005044//scavenger receptor activity;GO:0008233//peptidase activity,-
8099,0,0,0,0,63,0,1,0,12,0,2,0,CDK2AP1;cyclin-dependent kinase 2 associated protein 1,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0006261//DNA-dependent DNA replication;GO:0007049//cell cycle;GO:0001934//positive regulation of protein phosphorylation,GO:0070182//DNA polymerase binding,-
81,117,10,2,34,206,5,12,1,22,0,7,0,"ACTN4;actinin, alpha 4",GO:0043234//protein complex;GO:0031093//platelet alpha granule lumen;GO:0030863//cortical cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0043005//neuron projection;GO:0030529//ribonucleoprotein complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0030018//Z disc;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0031143//pseudopodium;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0001725//stress fiber,GO:0051017//actin filament bundle assembly;GO:0030168//platelet activation;GO:0070830//tight junction assembly;GO:0051271//negative regulation of cellular component movement;GO:0042981//regulation of apoptotic process;GO:0032417//positive regulation of sodium:proton antiporter activity;GO:0002576//platelet degranulation;GO:0015031//protein transport;GO:0051272//positive regulation of cellular component movement;GO:0001666//response to hypoxia;GO:0048549//positive regulation of pinocytosis;GO:0007596//blood coagulation,GO:0042803//protein homodimerization activity;GO:0001882//nucleoside binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0044822//poly(A) RNA binding;GO:0005509//calcium ion binding;GO:0047485//protein N-terminus binding;GO:0003779//actin binding;GO:0051015//actin filament binding,K05699//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Leukocyte transendothelial migration;Systemic lupus erythematosus;Regulation of actin cytoskeleton;Adherens junction;Amoebiasis;Focal adhesion
810,0,0,0,0,0,0,0,0,21,119,0,0,CALML3;calmodulin-like 3,GO:0070062//extracellular vesicular exosome,-,GO:0005509//calcium ion binding;GO:0005515//protein binding,K02183//Neurotrophin signaling pathway;Alzheimer's disease;Melanogenesis;Glioma;Gastric acid secretion;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Vascular smooth muscle contraction;Oocyte meiosis;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Insulin signaling pathway;Phototransduction;GnRH signaling pathway;Phosphatidylinositol signaling system;Dopaminergic synapse;Long-term potentiation;Alcoholism;Pertussis;Tuberculosis
8100,0,0,0,17,0,39,44,0,24,87,10,0,IFT88;intraflagellar transport 88,GO:0032391//photoreceptor connecting cilium;GO:0005929//cilium;GO:0060091//kinocilium;GO:0005814//centriole;GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B;GO:0045177//apical part of cell;GO:0002080//acrosomal membrane;GO:0031512//motile primary cilium;GO:0036064//ciliary basal body;GO:0097546//ciliary base,GO:0031122//cytoplasmic microtubule organization;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0008104//protein localization;GO:0007288//sperm axoneme assembly;GO:0031016//pancreas development;GO:0008589//regulation of smoothened signaling pathway;GO:0042733//embryonic digit morphogenesis;GO:0008544//epidermis development;GO:0034405//response to fluid shear stress;GO:0060411//cardiac septum morphogenesis;GO:0090102//cochlea development;GO:0055007//cardiac muscle cell differentiation;GO:0060122//inner ear receptor stereocilium organization;GO:2000785//regulation of autophagic vacuole assembly;GO:0007290//spermatid nucleus elongation;GO:0007219//Notch signaling pathway;GO:0043568//positive regulation of insulin-like growth factor receptor signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0045598//regulation of fat cell differentiation;GO:0060021//palate development;GO:0003382//epithelial cell morphogenesis;GO:0001654//eye development;GO:0001822//kidney development;GO:0001889//liver development;GO:0060914//heart formation;GO:0060271//cilium morphogenesis;GO:0021513//spinal cord dorsal/ventral patterning;GO:1902017//regulation of cilium assembly;GO:0070613//regulation of protein processing;GO:0048853//forebrain morphogenesis;GO:0007368//determination of left/right symmetry;GO:0021537//telencephalon development;GO:0007224//smoothened signaling pathway;GO:0060426//lung vasculature development;GO:0009952//anterior/posterior pattern specification,-,K09667//Other types of O-glycan biosynthesis
81027,0,0,0,0,8,0,0,0,0,0,0,0,"TUBB1;tubulin, beta 1 class VI",GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome,GO:0051258//protein polymerization;GO:0051225//spindle assembly;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0006184//GTP catabolic process;GO:0044267//cellular protein metabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005200//structural constituent of cytoskeleton,K07375//Phagosome;Gap junction;Pathogenic Escherichia coli infection
81029,0,0,0,0,4,10,13,0,6,0,0,0,"WNT5B;wingless-type MMTV integration site family, member 5B",GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005788//endoplasmic reticulum lumen;GO:0005796//Golgi lumen;GO:0005615//extracellular space,GO:0002062//chondrocyte differentiation;GO:0070307//lens fiber cell development;GO:0030335//positive regulation of cell migration;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0030182//neuron differentiation;GO:0071300//cellular response to retinoic acid;GO:0042060//wound healing;GO:0016055//Wnt signaling pathway;GO:0045600//positive regulation of fat cell differentiation;GO:0045165//cell fate commitment;GO:0045444//fat cell differentiation,GO:0005102//receptor binding;GO:0005109//frizzled binding,K00444//Melanogenesis;Basal cell carcinoma;HTLV-I infection;Wnt signaling pathway;Hedgehog signaling pathway;Pathways in cancer
81030,0,0,0,0,0,0,0,31,13,0,0,0,ZBP1;Z-DNA binding protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0008152//metabolic process;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production,GO:0003692//left-handed Z-DNA binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003726//double-stranded RNA adenosine deaminase activity;GO:0003723//RNA binding,K12965//Cytosolic DNA-sensing pathway
81031,0,0,0,0,17,33,20,0,41,0,0,0,"SLC2A10;solute carrier family 2 (facilitated glucose transporter), member 10",GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0015758//glucose transport;GO:0015992//proton transport;GO:0055085//transmembrane transport,GO:0005351//sugar:proton symporter activity,-
81033,104,0,11,0,0,0,0,0,47,31,0,0,"KCNH6;potassium voltage-gated channel, subfamily H (eag-related), member 6",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0042391//regulation of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport;GO:0007165//signal transduction,GO:0004871//signal transducer activity;GO:0005249//voltage-gated potassium channel activity,-
81034,0,91,0,31,3,0,71,44,15,0,59,0,"SLC25A32;solute carrier family 25 (mitochondrial folate carrier), member 32",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006839//mitochondrial transport;GO:0006766//vitamin metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0015884//folic acid transport;GO:0046655//folic acid metabolic process,GO:0008517//folic acid transporter activity,-
81035,19,0,0,1,1,6,2,0,18,0,0,0,COLEC12;collectin sub-family member 12,GO:0005581//collagen trimer;GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,"GO:0045087//innate immune response;GO:0006898//receptor-mediated endocytosis;GO:0006952//defense response;GO:0009756//carbohydrate mediated signaling;GO:0051260//protein homooligomerization;GO:0002221//pattern recognition receptor signaling pathway;GO:0006910//phagocytosis, recognition",GO:0005534//galactose binding;GO:0008329//signaling pattern recognition receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0046872//metal ion binding;GO:0005044//scavenger receptor activity,K10062//Phagosome
81037,80,0,0,3,27,11,55,0,25,0,11,0,CLPTM1L;CLPTM1-like,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006915//apoptotic process,-,-
8106,0,0,0,18,1,14,27,42,0,0,0,0,"PABPN1;poly(A) binding protein, nuclear 1",GO:0030529//ribonucleoprotein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006396//RNA processing;GO:0019058//viral life cycle;GO:0031124//mRNA 3'-end processing;GO:0016973//poly(A)+ mRNA export from nucleus;GO:0046778//modification by virus of host mRNA processing;GO:0019054//modulation by virus of host process;GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0019048//modulation by virus of host morphology or physiology;GO:0006369//termination of RNA polymerase II transcription;GO:0006936//muscle contraction;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,K14396//Influenza A;mRNA surveillance pathway
81061,0,0,0,0,0,0,0,0,11,0,0,0,"OR11H1;olfactory receptor, family 11, subfamily H, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81099,1,0,0,0,0,1,0,0,12,0,0,0,"OR4F17;olfactory receptor, family 4, subfamily F, member 17",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
811,0,65,0,11,10,0,0,0,51,0,9,0,CALR;calreticulin,GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0016020//membrane;GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix;GO:0071682//endocytic vesicle lumen;GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005844//polysome;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0033018//sarcoplasmic reticulum lumen;GO:0005622//intracellular;GO:0001669//acrosomal vesicle;GO:0042824//MHC class I peptide loading complex;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,"GO:0018279//protein N-linked glycosylation via asparagine;GO:0008284//positive regulation of cell proliferation;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0010628//positive regulation of gene expression;GO:0071285//cellular response to lithium ion;GO:0002502//peptide antigen assembly with MHC class I protein complex;GO:0032355//response to estradiol;GO:0050766//positive regulation of phagocytosis;GO:0007050//cell cycle arrest;GO:0017148//negative regulation of translation;GO:0045787//positive regulation of cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0007283//spermatogenesis;GO:0040020//regulation of meiosis;GO:0030866//cortical actin cytoskeleton organization;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006611//protein export from nucleus;GO:0006355//regulation of transcription, DNA-templated;GO:0090398//cellular senescence;GO:0022417//protein maturation by protein folding;GO:0006874//cellular calcium ion homeostasis;GO:0042493//response to drug;GO:0050821//protein stabilization;GO:2000510//positive regulation of dendritic cell chemotaxis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0006457//protein folding;GO:0045665//negative regulation of neuron differentiation;GO:0033574//response to testosterone;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0043687//post-translational protein modification;GO:0042981//regulation of apoptotic process;GO:0061077//chaperone-mediated protein folding;GO:0042921//glucocorticoid receptor signaling pathway;GO:0033144//negative regulation of intracellular steroid hormone receptor signaling pathway;GO:0044267//cellular protein metabolic process;GO:0051208//sequestering of calcium ion;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034504//protein localization to nucleus;GO:0045740//positive regulation of DNA replication;GO:0055007//cardiac muscle cell differentiation",GO:0051082//unfolded protein binding;GO:0005509//calcium ion binding;GO:0001849//complement component C1q binding;GO:0042277//peptide binding;GO:0005506//iron ion binding;GO:0030246//carbohydrate binding;GO:0031625//ubiquitin protein ligase binding;GO:0050681//androgen receptor binding;GO:0042562//hormone binding;GO:0044183//protein binding involved in protein folding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005178//integrin binding;GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0051087//chaperone binding;GO:0001948//glycoprotein binding,K08057//Antigen processing and presentation;Chagas disease (American trypanosomiasis);Protein processing in endoplasmic reticulum;HTLV-I infection;Phagosome
8110,96,0,0,0,0,18,44,0,20,0,7,23,"DPF3;D4, zinc and double PHD fingers, family 3",GO:0071565//nBAF complex,"GO:0006351//transcription, DNA-templated;GO:0007399//nervous system development;GO:0016568//chromatin modification;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding,-
8111,0,10,0,0,0,0,3,3,10,0,0,0,GPR68;G protein-coupled receptor 68,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006954//inflammatory response;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0045656//negative regulation of monocyte differentiation;GO:0007186//G-protein coupled receptor signaling pathway;GO:2001206//positive regulation of osteoclast development;GO:0071467//cellular response to pH,GO:0004930//G-protein coupled receptor activity,-
81127,0,0,0,0,0,0,0,0,10,0,0,0,"OR4K15;olfactory receptor, family 4, subfamily K, member 15",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
8115,43,0,0,0,0,0,0,0,12,0,3,0,TCL1A;T-cell leukemia/lymphoma 1A,GO:0005783//endoplasmic reticulum;GO:0045120//pronucleus;GO:0005938//cell cortex,GO:0007275//multicellular organismal development;GO:0019827//stem cell maintenance,GO:0005515//protein binding,-
81168,0,0,2,0,0,0,33,0,8,0,0,0,"OR8J3;olfactory receptor, family 8, subfamily J, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
8120,87,0,0,0,16,35,35,0,72,0,17,0,"AP3B2;adaptor-related protein complex 3, beta 2 subunit",GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0030137//COPI-coated vesicle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0030123//AP-3 adaptor complex;GO:0030665//clathrin-coated vesicle membrane,GO:0006892//post-Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0048490//anterograde synaptic vesicle transport;GO:0008089//anterograde axon cargo transport,GO:0005215//transporter activity,K12397//Lysosome
8125,0,61,1,92,290,0,30,0,18,0,0,0,"ANP32A;acidic (leucine-rich) nuclear phosphoprotein 32 family, member A",GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005783//endoplasmic reticulum,"GO:0006913//nucleocytoplasmic transport;GO:0006351//transcription, DNA-templated;GO:0010467//gene expression;GO:0035556//intracellular signal transduction;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0016071//mRNA metabolic process",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K11092//Spliceosome
8128,0,0,0,0,0,31,25,0,18,0,0,0,"ST8SIA2;ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2",GO:0000139//Golgi membrane;GO:0005769//early endosome;GO:0030173//integral component of Golgi membrane;GO:0055037//recycling endosome,GO:0007411//axon guidance;GO:0007399//nervous system development;GO:0044267//cellular protein metabolic process;GO:0001574//ganglioside biosynthetic process;GO:0043687//post-translational protein modification;GO:0005975//carbohydrate metabolic process;GO:0009311//oligosaccharide metabolic process;GO:0006491//N-glycan processing;GO:0006464//cellular protein modification process;GO:0006486//protein glycosylation;GO:0097503//sialylation;GO:0018279//protein N-linked glycosylation via asparagine,"GO:0003828//alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0033691//sialic acid binding",-
81282,0,0,0,0,0,0,0,0,13,0,0,0,"OR51G2;olfactory receptor, family 51, subfamily G, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81285,0,0,0,0,0,0,0,0,8,0,0,0,"OR51E2;olfactory receptor, family 51, subfamily E, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:1900135//positive regulation of renin secretion into blood stream;GO:0043401//steroid hormone mediated signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0071398//cellular response to fatty acid;GO:0045777//positive regulation of blood pressure;GO:0007186//G-protein coupled receptor signaling pathway,GO:0038023//signaling receptor activity;GO:0004984//olfactory receptor activity;GO:0003707//steroid hormone receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
813,0,0,14,11,53,30,7,0,48,0,0,0,CALU;calumenin,GO:0033018//sarcoplasmic reticulum lumen;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome;GO:0005576//extracellular region;GO:0005794//Golgi apparatus,GO:0007596//blood coagulation;GO:0002576//platelet degranulation;GO:0030168//platelet activation,GO:0005509//calcium ion binding;GO:0005515//protein binding,-
8131,0,0,0,8,9,1,0,45,48,0,0,0,NPRL3;nitrogen permease regulator-like 3 (S. cerevisiae),-,GO:0035909//aorta morphogenesis;GO:0003281//ventricular septum development;GO:0043547//positive regulation of GTPase activity;GO:0060021//palate development;GO:0048738//cardiac muscle tissue development,GO:0005096//GTPase activator activity,K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
81318,98,0,0,0,0,0,0,0,33,0,0,317,"OR4A5;olfactory receptor, family 4, subfamily A, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81328,0,0,0,0,0,0,1,0,0,0,0,0,"OR4A15;olfactory receptor, family 4, subfamily A, member 15",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81341,0,0,0,0,0,0,0,0,14,0,0,0,"OR10W1;olfactory receptor, family 10, subfamily W, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81343,0,0,0,0,0,16,0,0,0,0,0,0,"OR10V2P;olfactory receptor, family 10, subfamily V, member 2 pseudogene",-,-,-,K04257//Olfactory transduction
8139,0,0,0,8,11,16,19,1,1,133,0,0,GAN;gigaxonin,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0016567//protein ubiquitination;GO:0008219//cell death,GO:0005515//protein binding,-
814,0,0,0,0,0,14,0,0,33,0,0,0,CAMK4;calcium/calmodulin-dependent protein kinase IV,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,"GO:0007173//epidermal growth factor receptor signaling pathway;GO:0046827//positive regulation of protein export from nucleus;GO:0006954//inflammatory response;GO:0006913//nucleocytoplasmic transport;GO:0007616//long-term memory;GO:0007165//signal transduction;GO:0033081//regulation of T cell differentiation in thymus;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0045670//regulation of osteoclast differentiation;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045087//innate immune response;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0043011//myeloid dendritic cell differentiation;GO:0002372//myeloid dendritic cell cytokine production;GO:0007270//neuron-neuron synaptic transmission;GO:0007202//activation of phospholipase C activity",GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0004683//calmodulin-dependent protein kinase activity,K05869//Neurotrophin signaling pathway;Cholinergic synapse;Osteoclast differentiation;Amphetamine addiction;Long-term potentiation;Calcium signaling pathway;Alcoholism
8140,0,0,0,0,0,0,28,0,23,0,0,0,"SLC7A5;solute carrier family 7 (amino acid transporter light chain, L system), member 5",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus,GO:0006811//ion transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0015804//neutral amino acid transport;GO:0007596//blood coagulation;GO:0006810//transport;GO:0006520//cellular amino acid metabolic process;GO:0007399//nervous system development;GO:0055085//transmembrane transport;GO:0006865//amino acid transport;GO:0030154//cell differentiation;GO:0050900//leukocyte migration,GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity;GO:0015171//amino acid transmembrane transporter activity;GO:0042605//peptide antigen binding,-
81442,0,0,0,0,0,0,0,0,3,0,0,0,"OR6N2;olfactory receptor, family 6, subfamily N, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
81448,0,0,11,0,0,0,0,0,0,0,0,0,"OR6K2;olfactory receptor, family 6, subfamily K, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
81466,0,0,0,0,0,0,0,0,8,0,0,0,"OR2L5;olfactory receptor, family 2, subfamily L, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
81470,0,0,0,0,0,0,0,0,2,0,0,0,"OR2G2;olfactory receptor, family 2, subfamily G, member 2",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
81472,0,0,39,0,0,12,0,0,50,0,0,0,"OR2C3;olfactory receptor, family 2, subfamily C, member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
8148,0,0,0,0,77,0,0,66,79,0,0,0,"TAF15;TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0045893//positive regulation of transcription, DNA-templated",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,K14651//Basal transcription factors;Transcriptional misregulation in cancer
81488,0,0,1,0,0,0,11,0,0,0,8,0,POLR2M;polymerase (RNA) II (DNA directed) polypeptide M,"GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005635//nuclear envelope;GO:0043025//neuronal cell body",GO:0032774//RNA biosynthetic process;GO:0051685//maintenance of ER location,GO:0003899//DNA-directed RNA polymerase activity,-
81490,0,0,0,0,0,0,27,0,24,28,14,134,PTDSS2;phosphatidylserine synthase 2,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006644//phospholipid metabolic process;GO:0006659//phosphatidylserine biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0003882//CDP-diacylglycerol-serine O-phosphatidyltransferase activity,K08730//Metabolic pathways;Glycerophospholipid metabolism
81491,79,0,0,6,7,0,26,26,36,0,6,0,GPR63;G protein-coupled receptor 63,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
81492,0,0,0,0,0,18,19,0,51,0,0,0,RSPH6A;radial spoke head 6 homolog A (Chlamydomonas),GO:0005622//intracellular,-,-,K04700//Jak-STAT signaling pathway
81493,0,734,565,1359,2236,0,25,9,39,116,629,0,"SYNC;syncoilin, intermediate filament protein",GO:0031594//neuromuscular junction;GO:0042383//sarcolemma;GO:0005882//intermediate filament;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0030018//Z disc,-,GO:0005198//structural molecule activity,-
81494,0,0,0,0,0,18,0,0,19,5,9,0,CFHR5;complement factor H-related 5,GO:0005576//extracellular region,"GO:0006957//complement activation, alternative pathway",-,K04004//Complement and coagulation cascades;Staphylococcus aureus infection
815,0,0,0,0,0,13,0,101,34,0,5,0,CAMK2A;calcium/calmodulin-dependent protein kinase II alpha,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0030666//endocytic vesicle membrane;GO:0005829//cytosol,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046777//protein autophosphorylation;GO:0048168//regulation of neuronal synaptic plasticity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0046928//regulation of neurotransmitter secretion;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007268//synaptic transmission;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0006816//calcium ion transport,GO:0005524//ATP binding;GO:0035254//glutamate receptor binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding;GO:0016301//kinase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K04515//Wnt signaling pathway;Oocyte meiosis;Amphetamine addiction;ErbB signaling pathway;Phototransduction - fly;GnRH signaling pathway;Dopaminergic synapse;Long-term potentiation;Tuberculosis;Neurotrophin signaling pathway;Melanogenesis;Gastric acid secretion;Glioma;Cholinergic synapse;Calcium signaling pathway;Olfactory transduction
81501,0,0,0,0,0,0,0,0,14,0,0,0,DCSTAMP;dendrocyte expressed seven transmembrane protein,GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0010008//endosome membrane,GO:0030308//negative regulation of cell growth;GO:0034241//positive regulation of macrophage fusion;GO:0030316//osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0061025//membrane fusion;GO:0043011//myeloid dendritic cell differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:0072675//osteoclast fusion;GO:0036006//cellular response to macrophage colony-stimulating factor stimulus;GO:0045657//positive regulation of monocyte differentiation;GO:0071353//cellular response to interleukin-4,GO:0005515//protein binding,-
81502,0,0,0,0,0,0,1,0,22,0,0,0,HM13;histocompatibility (minor) 13,GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0005791//rough endoplasmic reticulum;GO:0009986//cell surface;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0006509//membrane protein ectodomain proteolysis;GO:0033619//membrane protein proteolysis;GO:0031293//membrane protein intracellular domain proteolysis,"GO:0008233//peptidase activity;GO:0042803//protein homodimerization activity;GO:0042500//aspartic endopeptidase activity, intramembrane cleaving;GO:0005515//protein binding",-
8153,0,0,0,0,0,0,0,0,0,0,13,0,RND2;Rho family GTPase 2,GO:0002080//acrosomal membrane;GO:0005769//early endosome,GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0048672//positive regulation of collateral sprouting;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0047485//protein N-terminus binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
81532,0,0,0,0,0,6,0,0,0,0,13,0,MOB2;MOB kinase activator 2,GO:0005730//nucleolus;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0044306//neuron projection terminus;GO:0005737//cytoplasm,GO:0010976//positive regulation of neuron projection development;GO:0001934//positive regulation of protein phosphorylation;GO:0030036//actin cytoskeleton organization,GO:0046872//metal ion binding,K06685//Cell cycle - yeast
81533,0,0,92,5,44,10,0,57,32,0,9,113,ITFG1;integrin alpha FG-GAP repeat containing 1,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane,-,-,-
81537,0,0,1,0,1,0,0,0,4,0,7,0,SGPP1;sphingosine-1-phosphate phosphatase 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006668//sphinganine-1-phosphate metabolic process;GO:0016311//dephosphorylation;GO:0006665//sphingolipid metabolic process;GO:0006670//sphingosine metabolic process,GO:0042392//sphingosine-1-phosphate phosphatase activity,K04716//Sphingolipid metabolism
81539,58,0,1,15,87,45,23,0,46,0,24,0,"SLC38A1;solute carrier family 38, member 1",GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0015804//neutral amino acid transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0001504//neurotransmitter uptake;GO:0007268//synaptic transmission;GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0006814//sodium ion transport,GO:0015175//neutral amino acid transmembrane transporter activity;GO:0005283//sodium:amino acid symporter activity,K14990//Glutamatergic synapse;GABAergic synapse
81542,0,0,0,0,0,18,0,50,8,0,4,0,TMX1;thioredoxin-related transmembrane protein 1,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0005789//endoplasmic reticulum membrane,GO:0006457//protein folding;GO:0055114//oxidation-reduction process;GO:0034976//response to endoplasmic reticulum stress;GO:0045454//cell redox homeostasis,GO:0003756//protein disulfide isomerase activity;GO:0015036//disulfide oxidoreductase activity,K09580//Protein processing in endoplasmic reticulum;K09584//Protein processing in endoplasmic reticulum;K09582//Vibrio cholerae infection;Protein processing in endoplasmic reticulum;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
81543,0,0,0,0,0,0,7,0,0,0,3,0,LRRC3;leucine rich repeat containing 3,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K07523//Axon guidance;K11447//Transcriptional misregulation in cancer
81544,98,0,0,0,0,34,57,55,54,0,0,0,GDPD5;glycerophosphodiester phosphodiesterase domain containing 5,GO:0030426//growth cone;GO:0048471//perinuclear region of cytoplasm;GO:0012505//endomembrane system;GO:0016021//integral component of membrane,GO:0021522//spinal cord motor neuron differentiation;GO:0021895//cerebral cortex neuron differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0048505//regulation of timing of cell differentiation;GO:0006071//glycerol metabolic process;GO:0006629//lipid metabolic process;GO:0031175//neuron projection development;GO:0045666//positive regulation of neuron differentiation,GO:0008889//glycerophosphodiester phosphodiesterase activity,-
81545,0,0,0,13,128,31,0,70,79,0,0,116,FBXO38;F-box protein 38,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008219//cell death,-,-
81550,0,0,0,12,33,27,12,67,23,0,10,15,TDRD3;tudor domain containing 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0035145//exon-exon junction complex,GO:0016568//chromatin modification;GO:2001141//regulation of RNA biosynthetic process,GO:0003682//chromatin binding;GO:0003713//transcription coactivator activity;GO:0044822//poly(A) RNA binding;GO:0035064//methylated histone binding,K10990//Fanconi anemia pathway
81551,0,0,0,0,0,15,5,31,6,0,0,0,STMN4;stathmin-like 4,GO:0030424//axon;GO:0005794//Golgi apparatus;GO:0030426//growth cone,GO:0031110//regulation of microtubule polymerization or depolymerization,-,K04381//MAPK signaling pathway
81552,0,25,0,23,16,7,0,58,32,12,1,0,"VOPP1;vesicular, overexpressed in cancer, prosurvival protein 1",GO:0005768//endosome;GO:0031301//integral component of organelle membrane;GO:0030659//cytoplasmic vesicle membrane,"GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0004871//signal transducer activity,-
81553,6,57,0,21,67,0,1,0,8,0,0,0,"FAM49A;family with sequence similarity 49, member A",GO:0005622//intracellular,-,-,-
81554,0,50,0,5,18,0,0,1,9,0,28,0,WBSCR16;Williams-Beuren syndrome chromosome region 16,-,-,GO:0044822//poly(A) RNA binding,K10614//Ubiquitin mediated proteolysis;K10615//Ubiquitin mediated proteolysis
81555,0,20,1,9,17,28,1,0,0,0,0,0,"YIPF5;Yip1 domain family, member 5",GO:0005789//endoplasmic reticulum membrane;GO:0070971//endoplasmic reticulum exit site;GO:0030134//ER to Golgi transport vesicle;GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0060628//regulation of ER to Golgi vesicle-mediated transport,-,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K12603//RNA degradation;K00102//Pyruvate metabolism
81556,0,13,0,5,10,0,0,41,17,0,2,0,VWA9;von Willebrand factor A domain containing 9,-,-,-,-
81558,0,0,0,13,0,0,0,0,0,0,0,0,"FAM117A;family with sequence similarity 117, member A",-,-,-,-
81559,0,0,1,0,5,0,0,0,13,0,11,0,TRIM11;tripartite motif containing 11,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0046597//negative regulation of viral entry into host cell;GO:1902187//negative regulation of viral release from host cell;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:0045892//negative regulation of transcription, DNA-templated;GO:0050768//negative regulation of neurogenesis;GO:0046598//positive regulation of viral entry into host cell;GO:0045087//innate immune response;GO:0051607//defense response to virus",GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0019904//protein domain specific binding,-
81562,128,0,0,0,0,31,27,8,24,0,0,44,"LMAN2L;lectin, mannose-binding 2-like",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0030134//ER to Golgi transport vesicle;GO:0005789//endoplasmic reticulum membrane,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport;GO:0006457//protein folding,GO:0005537//mannose binding;GO:0046872//metal ion binding,-
81563,105,223,20,84,310,14,22,5,122,1,28,0,C1orf21;chromosome 1 open reading frame 21,-,-,-,-
81565,0,0,0,22,5,0,0,0,9,0,2,0,NDEL1;nudE neurodevelopment protein 1-like 1,GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0031252//cell leading edge;GO:0005819//spindle;GO:0043203//axon hillock;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0060053//neurofilament cytoskeleton;GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005730//nucleolus;GO:0005874//microtubule;GO:0005635//nuclear envelope,GO:0045773//positive regulation of axon extension;GO:1990138//neuron projection extension;GO:0032864//activation of Cdc42 GTPase activity;GO:0001833//inner cell mass cell proliferation;GO:0021955//central nervous system neuron axonogenesis;GO:0051642//centrosome localization;GO:0021799//cerebral cortex radially oriented cell migration;GO:0048680//positive regulation of axon regeneration;GO:0000278//mitotic cell cycle;GO:0047496//vesicle transport along microtubule;GO:0051081//nuclear envelope disassembly;GO:0006508//proteolysis;GO:0007059//chromosome segregation;GO:0001764//neuron migration;GO:0007100//mitotic centrosome separation;GO:0060052//neurofilament cytoskeleton organization;GO:0008090//retrograde axon cargo transport,GO:0008017//microtubule binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0048487//beta-tubulin binding,K06560//Tuberculosis;Phagosome
81566,0,0,0,0,49,20,0,66,29,34,0,0,CSRNP2;cysteine-serine-rich nuclear protein 2,GO:0005634//nucleus,"GO:0010923//negative regulation of phosphatase activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0019902//phosphatase binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,-
81567,42,0,0,0,0,8,0,0,0,0,0,0,TXNDC5;thioredoxin domain containing 5 (endoplasmic reticulum),GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen;GO:0043202//lysosomal lumen,GO:0043277//apoptotic cell clearance;GO:0043066//negative regulation of apoptotic process;GO:0061024//membrane organization;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006457//protein folding,GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K13984//Protein processing in endoplasmic reticulum
81569,0,0,0,0,0,0,0,37,0,0,0,0,ACTL8;actin-like 8,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,GO:0030855//epithelial cell differentiation,-,K05692//Adherens junction;Phototransduction - fly;Viral myocarditis;Influenza A;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction
81570,21,28,0,4,0,19,4,1,78,0,15,0,CLPB;ClpB caseinolytic peptidase B homolog (E. coli),GO:0005739//mitochondrion,GO:0034605//cellular response to heat,GO:0005524//ATP binding,-
81572,0,38,0,15,0,0,0,0,10,0,0,0,PDRG1;p53 and DNA-damage regulated 1,GO:0005737//cytoplasm;GO:0016272//prefoldin complex,GO:0006457//protein folding,GO:0051082//unfolded protein binding,-
81573,0,0,0,49,90,24,5,0,25,0,0,0,ANKRD13C;ankyrin repeat domain 13C,GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm,GO:0010869//regulation of receptor biosynthetic process;GO:0006621//protein retention in ER lumen;GO:2000209//regulation of anoikis,GO:0005102//receptor binding,-
81575,0,0,0,0,0,0,38,0,12,0,0,486,APOLD1;apolipoprotein L domain containing 1,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0006869//lipid transport;GO:0001525//angiogenesis;GO:0001666//response to hypoxia;GO:0042157//lipoprotein metabolic process;GO:0042118//endothelial cell activation;GO:0030154//cell differentiation,GO:0008289//lipid binding,K11447//Transcriptional misregulation in cancer;K14480//African trypanosomiasis;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
81576,0,0,0,0,0,16,0,0,0,0,9,0,CCDC130;coiled-coil domain containing 130,-,GO:0009615//response to virus,GO:0005515//protein binding,-
81577,0,0,0,0,16,38,24,41,48,0,14,0,GFOD2;glucose-fructose oxidoreductase domain containing 2,GO:0005578//proteinaceous extracellular matrix,GO:0030198//extracellular matrix organization;GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K11447//Transcriptional misregulation in cancer
81578,0,0,0,0,0,38,0,0,31,8,18,0,"COL21A1;collagen, type XXI, alpha 1",GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer;GO:0031012//extracellular matrix;GO:0005788//endoplasmic reticulum lumen,GO:0030198//extracellular matrix organization,-,K08132//Protein digestion and absorption
81579,0,0,1,37,25,0,27,42,31,0,0,0,"PLA2G12A;phospholipase A2, group XIIA",GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0005576//extracellular region,GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016042//lipid catabolic process;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036151//phosphatidylcholine acyl-chain remodeling,GO:0047498//calcium-dependent phospholipase A2 activity;GO:0005509//calcium ion binding,K01047//Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Toxoplasmosis;Arachidonic acid metabolism;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism;GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;Metabolic pathways;Vascular smooth muscle contraction;Linoleic acid metabolism;MAPK signaling pathway;Glutamatergic synapse
816,195,0,0,0,9,16,0,58,67,0,278,6,CAMK2B;calcium/calmodulin-dependent protein kinase II beta,GO:0033017//sarcoplasmic reticulum membrane;GO:0005815//microtubule organizing center;GO:0005654//nucleoplasm;GO:0051233//spindle midzone;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane,"GO:0032222//regulation of synaptic transmission, cholinergic;GO:0050885//neuromuscular process controlling balance;GO:0006816//calcium ion transport;GO:0061003//positive regulation of dendritic spine morphogenesis;GO:0046686//response to cadmium ion;GO:0060998//regulation of dendritic spine development;GO:0002030//inhibitory G-protein coupled receptor phosphorylation;GO:0090129//positive regulation of synapse maturation;GO:0014733//regulation of skeletal muscle adaptation;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060466//activation of meiosis involved in egg activation;GO:0051924//regulation of calcium ion transport;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0051823//regulation of synapse structural plasticity;GO:0019221//cytokine-mediated signaling pathway;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0046777//protein autophosphorylation;GO:0010976//positive regulation of neuron projection development;GO:0007165//signal transduction;GO:0018105//peptidyl-serine phosphorylation;GO:0000082//G1/S transition of mitotic cell cycle",GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding;GO:0003779//actin binding;GO:0042803//protein homodimerization activity,K04515//Amphetamine addiction;Oocyte meiosis;Wnt signaling pathway;Phototransduction - fly;ErbB signaling pathway;Dopaminergic synapse;GnRH signaling pathway;Tuberculosis;Long-term potentiation;Neurotrophin signaling pathway;Gastric acid secretion;Glioma;Melanogenesis;Cholinergic synapse;Olfactory transduction;Calcium signaling pathway
81602,0,0,0,0,31,14,0,12,12,0,0,0,CDADC1;cytidine and dCMP deaminase domain containing 1,-,GO:0008152//metabolic process,GO:0008270//zinc ion binding;GO:0016787//hydrolase activity,K01493//Metabolic pathways;Purine metabolism;Pyrimidine metabolism
81603,0,0,1,18,23,42,37,46,27,0,21,0,TRIM8;tripartite motif containing 8,GO:0016605//PML body;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016567//protein ubiquitination;GO:0032897//negative regulation of viral transcription;GO:1902187//negative regulation of viral release from host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0045087//innate immune response;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity,-
81605,0,0,0,2,0,6,0,0,11,0,0,0,URM1;ubiquitin related modifier 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0002098//tRNA wobble uridine modification;GO:0032447//protein urmylation;GO:0034227//tRNA thio-modification,GO:0016783//sulfurtransferase activity;GO:0005515//protein binding,K12161//Sulfur relay system
81606,0,0,0,12,17,0,0,0,10,0,0,0,LBH;limb bud and heart development,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007275//multicellular organismal development;GO:0030193//regulation of blood coagulation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0010468//regulation of gene expression",-,-
81607,0,0,0,0,0,9,18,0,0,0,0,0,PVRL4;poliovirus receptor-related 4,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005912//adherens junction,GO:0007155//cell adhesion;GO:0034332//adherens junction organization;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0016032//viral process,GO:0005515//protein binding,K06593//Adherens junction
81608,0,0,0,54,93,11,0,0,42,0,0,0,FIP1L1;factor interacting with PAPOLA and CPSF1,GO:0005634//nucleus;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0005730//nucleolus,GO:0006397//mRNA processing,GO:0044822//poly(A) RNA binding,K14405//mRNA surveillance pathway
81609,0,70,1,38,70,0,54,0,28,0,33,0,SNX27;sorting nexin family member 27,GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0031901//early endosome membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0030904//retromer complex;GO:0005769//early endosome;GO:0071203//WASH complex,"GO:0016197//endosomal transport;GO:0007165//signal transduction;GO:1990126//retrograde transport, endosome to plasma membrane;GO:0006886//intracellular protein transport;GO:0008333//endosome to lysosome transport;GO:0001770//establishment of natural killer cell polarity",GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K15009//Glutamatergic synapse;K11447//Transcriptional misregulation in cancer
8161,0,0,0,10,9,0,46,0,46,0,0,0,COIL;coilin,GO:0005730//nucleolus;GO:0001674//female germ cell nucleus;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0015030//Cajal body,GO:0055114//oxidation-reduction process,GO:0015036//disulfide oxidoreductase activity;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0042802//identical protein binding,-
81610,0,0,0,0,0,28,0,19,0,0,0,0,"FAM83D;family with sequence similarity 83, member D",GO:0005737//cytoplasm;GO:0000922//spindle pole,GO:0007067//mitotic nuclear division,-,-
81611,0,0,0,7,30,0,0,0,60,0,0,0,"ANP32E;acidic (leucine-rich) nuclear phosphoprotein 32 family, member E",GO:0005634//nucleus;GO:0000812//Swr1 complex;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0043086//negative regulation of catalytic activity;GO:0043486//histone exchange,GO:0042393//histone binding;GO:0019212//phosphatase inhibitor activity,K11092//Spliceosome
81614,0,74,139,37,38,3,0,0,42,0,32,0,NIPA2;non imprinted in Prader-Willi/Angelman syndrome 2,GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Arginine and proline metabolism;Biotin metabolism;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K09057//Circadian rhythm - fly
81615,26,0,0,0,0,0,13,0,0,0,1,0,TMEM163;transmembrane protein 163,GO:0030285//integral component of synaptic vesicle membrane;GO:0030054//cell junction;GO:0031901//early endosome membrane,-,GO:0008270//zinc ion binding,-
81616,91,28,3,0,2,0,0,0,13,0,7,1,ACSBG2;acyl-CoA synthetase bubblegum family member 2,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0007283//spermatogenesis;GO:0006631//fatty acid metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0004467//long-chain fatty acid-CoA ligase activity;GO:0005524//ATP binding;GO:0047617//acyl-CoA hydrolase activity,K15013//Fatty acid metabolism;Adipocytokine signaling pathway;PPAR signaling pathway;Metabolic pathways
81617,0,114,4,100,398,9,9,0,22,0,0,1,CAB39L;calcium binding protein 39-like,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0008286//insulin receptor signaling pathway;GO:0007050//cell cycle arrest,-,K08272//mTOR signaling pathway
81618,0,0,0,0,13,0,23,0,22,198,13,0,ITM2C;integral membrane protein 2C,GO:0005764//lysosome;GO:0048471//perinuclear region of cytoplasm;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030182//neuron differentiation;GO:0010977//negative regulation of neuron projection development;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0001540//beta-amyloid binding,-
81619,3,0,0,0,0,0,0,0,16,0,4,0,TSPAN14;tetraspanin 14,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0097197//tetraspanin-enriched microdomain;GO:0005886//plasma membrane,GO:0045747//positive regulation of Notch signaling pathway;GO:0090002//establishment of protein localization to plasma membrane;GO:0051604//protein maturation,GO:0019899//enzyme binding,-
81620,0,0,0,0,0,20,0,0,12,0,0,183,CDT1;chromatin licensing and DNA replication factor 1,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0000076//DNA replication checkpoint;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0033262//regulation of nuclear cell cycle DNA replication;GO:0030174//regulation of DNA-dependent DNA replication initiation,GO:0005515//protein binding;GO:0003677//DNA binding,-
81621,0,0,0,2,0,0,0,64,0,0,6,404,KAZALD1;Kazal-type serine peptidase inhibitor domain 1,GO:0005614//interstitial matrix,GO:0001503//ossification;GO:0030154//cell differentiation;GO:0030198//extracellular matrix organization;GO:0001558//regulation of cell growth;GO:0007275//multicellular organismal development,GO:0005520//insulin-like growth factor binding,-
81622,0,1,0,0,0,0,4,0,34,0,1,0,UNC93B1;unc-93 homolog B1 (C. elegans),GO:0005789//endoplasmic reticulum membrane;GO:0005764//lysosome;GO:0032009//early phagosome;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005783//endoplasmic reticulum;GO:0005768//endosome,GO:0034138//toll-like receptor 3 signaling pathway;GO:0006886//intracellular protein transport;GO:0034154//toll-like receptor 7 signaling pathway;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0034162//toll-like receptor 9 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0035325//Toll-like receptor binding,-
81623,0,0,0,0,0,0,0,0,1,0,0,0,"DEFB126;defensin, beta 126",GO:0030112//glycocalyx;GO:0005576//extracellular region;GO:0009986//cell surface,GO:0042742//defense response to bacterium,-,-
81624,0,0,0,1,0,17,0,49,65,227,0,0,DIAPH3;diaphanous-related formin 3,GO:0005829//cytosol;GO:0005634//nucleus,GO:0030036//actin cytoskeleton organization;GO:0007283//spermatogenesis,GO:0017048//Rho GTPase binding;GO:0003779//actin binding,K05745//Regulation of actin cytoskeleton
81626,0,0,0,0,0,0,18,0,23,0,0,77,SHCBP1L;SHC SH2-domain binding protein 1-like,-,-,-,-
81627,0,0,0,9,16,1,0,0,0,0,0,0,TRMT1L;tRNA methyltransferase 1 homolog (S. cerevisiae)-like,-,GO:0008344//adult locomotory behavior;GO:0030488//tRNA methylation,GO:0000049//tRNA binding;GO:0004809//tRNA (guanine-N2-)-methyltransferase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding,-
81628,0,2,0,0,10,0,41,47,26,0,3,0,"TSC22D4;TSC22 domain family, member 4",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006970//response to osmotic stress;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
81629,108,1,31,3,0,0,0,58,0,0,9,0,TSSK3;testis-specific serine kinase 3,-,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
81631,0,1,1,54,189,0,53,0,28,0,0,0,MAP1LC3B;microtubule-associated protein 1 light chain 3 beta,GO:0005874//microtubule;GO:0000421//autophagic vacuole membrane;GO:0005776//autophagic vacuole;GO:0005930//axoneme;GO:0031090//organelle membrane;GO:0005622//intracellular;GO:0031410//cytoplasmic vesicle;GO:0012505//endomembrane system,GO:0006914//autophagy,GO:0005515//protein binding,-
8165,0,1,3,2,1,0,53,61,32,109,12,0,AKAP1;A kinase (PRKA) anchor protein 1,GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane,GO:0007596//blood coagulation,GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K14411//mRNA surveillance pathway
81669,0,0,0,0,0,0,0,0,17,0,10,0,CCNL2;cyclin L2,GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0006355//regulation of transcription, DNA-templated",GO:0019901//protein kinase binding,K15188//Transcriptional misregulation in cancer
81671,81,0,0,29,46,0,0,0,26,0,0,0,VMP1;vacuole membrane protein 1,GO:0000421//autophagic vacuole membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0000407//pre-autophagosomal structure;GO:0005886//plasma membrane,GO:0006914//autophagy;GO:0010506//regulation of autophagy;GO:0034329//cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0007566//embryo implantation,GO:0005515//protein binding,-
81688,0,24,1,139,300,0,0,0,39,0,0,0,C6orf62;chromosome 6 open reading frame 62,GO:0005622//intracellular,-,-,-
81689,0,0,0,17,17,0,0,0,0,0,0,0,ISCA1;iron-sulfur cluster assembly 1,GO:0005739//mitochondrion,GO:0016226//iron-sulfur cluster assembly,GO:0051536//iron-sulfur cluster binding;GO:0046872//metal ion binding;GO:0005198//structural molecule activity,-
81691,0,0,0,46,82,21,15,0,87,0,18,695,LOC81691;exonuclease NEF-sp,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0000166//nucleotide binding;GO:0004527//exonuclease activity;GO:0003723//RNA binding,K14570//Ribosome biogenesis in eukaryotes
81693,40,0,0,0,12,0,0,3,32,0,0,0,AMN;amnion associated transmembrane protein,GO:0030139//endocytic vesicle;GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016324//apical plasma membrane,GO:0015889//cobalamin transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0009235//cobalamin metabolic process;GO:0042157//lipoprotein metabolic process;GO:0043001//Golgi to plasma membrane protein transport;GO:0007275//multicellular organismal development;GO:0007588//excretion;GO:0006766//vitamin metabolic process;GO:0006898//receptor-mediated endocytosis,GO:0005102//receptor binding,-
81696,0,0,0,0,0,0,0,0,10,0,0,0,"OR5V1;olfactory receptor, family 5, subfamily V, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
81697,0,0,0,0,0,8,0,0,25,0,0,0,"OR2B2;olfactory receptor, family 2, subfamily B, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
817,61,164,1,78,220,15,0,48,111,0,0,0,CAMK2D;calcium/calmodulin-dependent protein kinase II delta,GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005886//plasma membrane;GO:0014704//intercalated disc;GO:0031594//neuromuscular junction;GO:0016020//membrane;GO:0030315//T-tubule;GO:0005634//nucleus;GO:0034704//calcium channel complex;GO:0033017//sarcoplasmic reticulum membrane;GO:0043194//axon initial segment;GO:0030666//endocytic vesicle membrane;GO:0005829//cytosol,GO:0086003//cardiac muscle cell contraction;GO:1901725//regulation of histone deacetylase activity;GO:1901844//regulation of cell communication by electrical coupling involved in cardiac conduction;GO:0032469//endoplasmic reticulum calcium ion homeostasis;GO:0008016//regulation of heart contraction;GO:0006816//calcium ion transport;GO:0055119//relaxation of cardiac muscle;GO:0010649//regulation of cell communication by electrical coupling;GO:0001558//regulation of cell growth;GO:0071277//cellular response to calcium ion;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0051259//protein oligomerization;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0060341//regulation of cellular localization;GO:1901897//regulation of relaxation of cardiac muscle;GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0019221//cytokine-mediated signaling pathway;GO:0006468//protein phosphorylation;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0007268//synaptic transmission;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0003254//regulation of membrane depolarization;GO:0018107//peptidyl-threonine phosphorylation;GO:0086091//regulation of heart rate by cardiac conduction;GO:2000650//negative regulation of sodium ion transmembrane transporter activity;GO:0000082//G1/S transition of mitotic cell cycle;GO:0018105//peptidyl-serine phosphorylation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0002026//regulation of the force of heart contraction;GO:1902306//negative regulation of sodium ion transmembrane transport;GO:0046777//protein autophosphorylation,GO:0031432//titin binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding;GO:0044325//ion channel binding;GO:0042803//protein homodimerization activity;GO:0004674//protein serine/threonine kinase activity;GO:0019871//sodium channel inhibitor activity,K04515//Neurotrophin signaling pathway;Melanogenesis;Gastric acid secretion;Glioma;Cholinergic synapse;Calcium signaling pathway;Olfactory transduction;Wnt signaling pathway;Oocyte meiosis;Amphetamine addiction;Phototransduction - fly;ErbB signaling pathway;GnRH signaling pathway;Dopaminergic synapse;Long-term potentiation;Tuberculosis
8170,1,0,57,0,0,0,35,0,70,67,29,0,"SLC14A2;solute carrier family 14 (urea transporter), member 2",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0015840//urea transport;GO:0071918//urea transmembrane transport;GO:0055085//transmembrane transport,GO:0005515//protein binding;GO:0015204//urea transmembrane transporter activity;GO:0050839//cell adhesion molecule binding,-
81704,170,13,1,16,14,51,1,0,64,44,71,0,DOCK8;dedicator of cytokinesis 8,GO:0031252//cell leading edge;GO:0005829//cytosol;GO:0016020//membrane,GO:0007264//small GTPase mediated signal transduction;GO:0070233//negative regulation of T cell apoptotic process;GO:0001771//immunological synapse formation;GO:0061485//memory T cell proliferation;GO:0036336//dendritic cell migration;GO:0007596//blood coagulation;GO:0043547//positive regulation of GTPase activity,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K13708//Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Focal adhesion;Shigellosis
81706,0,0,0,0,0,0,0,0,1,0,0,0,"PPP1R14C;protein phosphatase 1, regulatory (inhibitor) subunit 14C",GO:0005737//cytoplasm;GO:0016020//membrane,GO:0043086//negative regulation of catalytic activity;GO:0042325//regulation of phosphorylation,GO:0004865//protein serine/threonine phosphatase inhibitor activity,K05744//Axon guidance;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;K12328//Vascular smooth muscle contraction
8174,0,0,19,0,0,30,0,58,0,0,0,0,MADCAM1;mucosal vascular addressin cell adhesion molecule 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0007568//aging;GO:0009790//embryo development;GO:0043113//receptor clustering;GO:0050776//regulation of immune response;GO:0050901//leukocyte tethering or rolling;GO:0030198//extracellular matrix organization;GO:0002687//positive regulation of leukocyte migration;GO:0007165//signal transduction;GO:0007229//integrin-mediated signaling pathway;GO:0006955//immune response;GO:0007160//cell-matrix adhesion;GO:0030216//keratinocyte differentiation;GO:0034113//heterotypic cell-cell adhesion;GO:0007155//cell adhesion,-,K06779//Intestinal immune network for IgA production;Cell adhesion molecules (CAMs)
8175,5,0,0,1,0,11,0,0,0,0,1,0,"SF3A2;splicing factor 3a, subunit 2, 66kDa",GO:0005681//spliceosomal complex;GO:0071013//catalytic step 2 spliceosome;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0000389//mRNA 3'-splice site recognition",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,K12826//Spliceosome
8178,0,0,0,0,0,9,35,51,53,0,12,0,ELL;elongation factor RNA polymerase II,GO:0016607//nuclear speck;GO:0035327//transcriptionally active chromatin;GO:0008023//transcription elongation factor complex;GO:0005654//nucleoplasm;GO:0015030//Cajal body,"GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0010923//negative regulation of phosphatase activity;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0001701//in utero embryonic development;GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:0050434//positive regulation of viral transcription;GO:0042796//snRNA transcription from RNA polymerase III promoter",GO:0005515//protein binding;GO:0019902//phosphatase binding,-
81786,1,0,0,0,21,0,0,69,36,0,12,301,TRIM7;tripartite motif containing 7,GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0008270//zinc ion binding,-
81788,0,0,0,0,0,8,0,0,17,0,0,0,"NUAK2;NUAK family, SNF1-like kinase, 2",-,GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0042149//cellular response to glucose starvation;GO:0043066//negative regulation of apoptotic process;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
81789,1,324,62,146,333,17,36,3002,530,0,1061,5,TIGD6;tigger transposable element derived 6,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
81790,0,0,0,25,9,0,0,7,27,0,0,204,RNF170;ring finger protein 170,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
81792,80,0,0,0,0,6,31,32,26,0,11,0,"ADAMTS12;ADAM metallopeptidase with thrombospondin type 1 motif, 12",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:2001113//negative regulation of cellular response to hepatocyte growth factor stimulus;GO:0050727//regulation of inflammatory response;GO:0071347//cellular response to interleukin-1;GO:0007160//cell-matrix adhesion;GO:1902203//negative regulation of hepatocyte growth factor receptor signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:1902548//negative regulation of cellular response to vascular endothelial growth factor stimulus;GO:0030167//proteoglycan catabolic process;GO:0016477//cell migration;GO:0032331//negative regulation of chondrocyte differentiation;GO:0071356//cellular response to tumor necrosis factor;GO:1901509//regulation of endothelial tube morphogenesis;GO:0071773//cellular response to BMP stimulus,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
81793,9,0,0,0,0,0,0,0,35,0,0,0,TLR10;toll-like receptor 10,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0006954//inflammatory response;GO:0045087//innate immune response;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0050707//regulation of cytokine secretion;GO:0002224//toll-like receptor signaling pathway;GO:0006955//immune response;GO:0050729//positive regulation of inflammatory response;GO:0034166//toll-like receptor 10 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway,GO:0004888//transmembrane signaling receptor activity,-
81794,0,0,0,0,7,15,0,56,4,0,13,1,"ADAMTS10;ADAM metallopeptidase with thrombospondin type 1 motif, 10",GO:0001527//microfibril;GO:0031012//extracellular matrix,GO:0006508//proteolysis,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
81796,0,0,0,9,22,30,0,0,13,54,0,0,"SLCO5A1;solute carrier organic anion transporter family, member 5A1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006810//transport,GO:0005215//transporter activity,-
818,0,1,0,0,1,0,0,0,10,0,0,1,CAMK2G;calcium/calmodulin-dependent protein kinase II gamma,GO:0030666//endocytic vesicle membrane;GO:0005954//calcium- and calmodulin-dependent protein kinase complex;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0005654//nucleoplasm;GO:0033017//sarcoplasmic reticulum membrane,GO:0030073//insulin secretion;GO:0014733//regulation of skeletal muscle adaptation;GO:0030154//cell differentiation;GO:0051259//protein oligomerization;GO:0000082//G1/S transition of mitotic cell cycle;GO:0046777//protein autophosphorylation;GO:1901897//regulation of relaxation of cardiac muscle;GO:0016311//dephosphorylation;GO:0051924//regulation of calcium ion transport;GO:0006816//calcium ion transport;GO:0007399//nervous system development;GO:0019221//cytokine-mediated signaling pathway;GO:0007268//synaptic transmission;GO:0060333//interferon-gamma-mediated signaling pathway,GO:0004723//calcium-dependent protein serine/threonine phosphatase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K04515//Cholinergic synapse;Olfactory transduction;Calcium signaling pathway;Neurotrophin signaling pathway;Melanogenesis;Gastric acid secretion;Glioma;Dopaminergic synapse;GnRH signaling pathway;Long-term potentiation;Tuberculosis;Oocyte meiosis;Wnt signaling pathway;Amphetamine addiction;Phototransduction - fly;ErbB signaling pathway
81831,0,0,0,0,4,1,11,0,0,0,0,0,NETO2;neuropilin (NRP) and tolloid (TLL)-like 2,GO:0032983//kainate selective glutamate receptor complex;GO:0014069//postsynaptic density,GO:2000312//regulation of kainate selective glutamate receptor activity,GO:0035255//ionotropic glutamate receptor binding,K14616//Vitamin digestion and absorption
81832,1,0,0,0,0,0,56,1,27,0,4,0,NETO1;neuropilin (NRP) and tolloid (TLL)-like 1,GO:0005576//extracellular region;GO:0030054//cell junction;GO:0060076//excitatory synapse;GO:0032983//kainate selective glutamate receptor complex;GO:0045211//postsynaptic membrane;GO:0014069//postsynaptic density,GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0008542//visual learning;GO:0097120//receptor localization to synapse;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0007613//memory,GO:0035255//ionotropic glutamate receptor binding,K14616//Vitamin digestion and absorption
81839,0,0,0,4,0,29,0,0,75,0,2,0,VANGL1;VANGL planar cell polarity protein 1,GO:0016021//integral component of membrane;GO:0016328//lateral plasma membrane,GO:0007275//multicellular organismal development,GO:0005515//protein binding,K04510//Wnt signaling pathway
81844,1,0,0,0,12,18,0,42,16,0,0,0,TRIM56;tripartite motif containing 56,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0032608//interferon-beta production;GO:0070534//protein K63-linked ubiquitination;GO:1902187//negative regulation of viral release from host cell;GO:0034340//response to type I interferon;GO:0046597//negative regulation of viral entry into host cell;GO:0032481//positive regulation of type I interferon production;GO:0045087//innate immune response;GO:0051607//defense response to virus,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,-
81846,65,22,0,98,172,8,0,0,108,147,55,0,SBF2;SET binding factor 2,GO:0005774//vacuolar membrane;GO:0016020//membrane,GO:0051262//protein tetramerization;GO:0008219//cell death;GO:0016311//dephosphorylation;GO:0042552//myelination;GO:0032851//positive regulation of Rab GTPase activity,GO:0016791//phosphatase activity;GO:0035091//phosphatidylinositol binding;GO:0019902//phosphatase binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0019208//phosphatase regulator activity,K01112//Fructose and mannose metabolism
81847,0,0,0,17,68,0,19,4,17,0,0,269,RNF146;ring finger protein 146,GO:0005829//cytosol;GO:0005634//nucleus,GO:0016055//Wnt signaling pathway;GO:0070936//protein K48-linked ubiquitination;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0051865//protein autoubiquitination,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0072572//poly-ADP-D-ribose binding;GO:0008270//zinc ion binding,-
81848,0,25,0,0,11,10,4,7,20,0,0,0,SPRY4;sprouty homolog 4 (Drosophila),GO:0032587//ruffle membrane;GO:0005794//Golgi apparatus;GO:0005925//focal adhesion;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0043407//negative regulation of MAP kinase activity,GO:0005515//protein binding,K04704//Jak-STAT signaling pathway
81849,0,0,34,0,0,0,0,0,21,0,0,0,"ST6GALNAC5;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",GO:0030173//integral component of Golgi membrane,GO:0097503//sialylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0006486//protein glycosylation,"GO:0008373//sialyltransferase activity;GO:0001665//alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity",K03375//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
81853,0,26,0,67,163,0,0,0,0,0,1,0,TMEM14B;transmembrane protein 14B,GO:0016021//integral component of membrane,-,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
81855,0,33,0,0,1,0,0,0,20,0,1,0,SFXN3;sideroflexin 3,GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0055072//iron ion homeostasis,GO:0008324//cation transmembrane transporter activity,K03351//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Cell cycle - yeast;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
81856,0,40,0,15,32,0,41,0,6,0,11,0,ZNF611;zinc finger protein 611,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
81857,0,0,0,0,0,0,12,0,1,0,0,0,MED25;mediator complex subunit 25,GO:0005654//nucleoplasm,GO:2001178//positive regulation of mediator complex assembly;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0048147//negative regulation of fibroblast proliferation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0035563//positive regulation of chromatin binding;GO:0010467//gene expression;GO:0008219//cell death;GO:0071158//positive regulation of cell cycle arrest;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0046965//retinoid X receptor binding;GO:0042974//retinoic acid receptor binding;GO:0005515//protein binding;GO:0008134//transcription factor binding,-
81858,0,0,0,0,10,0,0,25,24,0,4,0,SHARPIN;SHANK-associated RH domain interactor,GO:0030425//dendrite;GO:0030054//cell junction;GO:0005829//cytosol;GO:0071797//LUBAC complex;GO:0014069//postsynaptic density,GO:0051260//protein homooligomerization;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0007005//mitochondrion organization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030262//apoptotic nuclear changes;GO:2000348//regulation of CD40 signaling pathway;GO:0097039//protein linear polyubiquitination;GO:0031424//keratinization;GO:0050728//negative regulation of inflammatory response;GO:0007420//brain development,GO:0032403//protein complex binding;GO:0008270//zinc ion binding;GO:0031593//polyubiquitin binding;GO:0042802//identical protein binding;GO:0005515//protein binding,-
8187,0,30,0,0,22,0,4,0,0,150,0,0,ZNF239;zinc finger protein 239,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003723//RNA binding,-
81870,97,0,0,0,0,10,0,0,0,0,0,0,KRTAP9-9;keratin associated protein 9-9,GO:0045095//keratin filament,-,-,-
81871,0,0,0,0,0,0,0,0,14,0,0,0,KRTAP4-6;keratin associated protein 4-6,GO:0045095//keratin filament,-,-,-
81872,0,0,0,0,0,10,0,0,16,0,0,0,KRTAP2-1;keratin associated protein 2-1,GO:0045095//keratin filament,-,-,-
81873,0,0,1,33,26,4,24,0,0,0,8,0,"ARPC5L;actin related protein 2/3 complex, subunit 5-like",GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome,GO:0030833//regulation of actin filament polymerization,GO:0003779//actin binding,K05754//Regulation of actin cytoskeleton;Salmonella infection;Bacterial invasion of epithelial cells;Shigellosis;Pathogenic Escherichia coli infection;Fc gamma R-mediated phagocytosis
81876,0,17,1,2,65,0,0,0,16,44,0,0,"RAB1B;RAB1B, member RAS oncogene family",GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0015031//protein transport;GO:0019068//virion assembly;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0005525//GTP binding,K07875//Legionellosis
81887,0,28,0,0,27,33,0,96,33,0,0,0,LAS1L;LAS1-like (S. cerevisiae),GO:0016020//membrane;GO:0005730//nucleolus;GO:0005815//microtubule organizing center;GO:0071339//MLL1 complex;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
81888,0,30,85,6,120,30,0,0,14,0,136,0,HYI;hydroxypyruvate isomerase (putative),-,GO:0008152//metabolic process,GO:0008903//hydroxypyruvate isomerase activity,K01816//Metabolic pathways;Glyoxylate and dicarboxylate metabolism
81889,0,0,0,9,49,0,31,0,6,0,0,0,FAHD1;fumarylacetoacetate hydrolase domain containing 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005743//mitochondrial inner membrane;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0018773//acetylpyruvate hydrolase activity;GO:0047621//acylpyruvate hydrolase activity;GO:0046872//metal ion binding;GO:0034545//fumarylpyruvate hydrolase activity,K01557//Metabolic pathways;Tyrosine metabolism
8189,23,1,0,0,1,15,13,2,27,36,1,0,SYMPK;symplekin,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0007155//cell adhesion;GO:0006378//mRNA polyadenylation;GO:0035307//positive regulation of protein dephosphorylation,GO:0005515//protein binding,K06100//mRNA surveillance pathway;Tight junction
81890,0,0,0,0,0,32,0,1,31,39,0,0,QTRT1;queuine tRNA-ribosyltransferase 1,GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0006400//tRNA modification;GO:0008616//queuosine biosynthetic process,GO:0046872//metal ion binding;GO:0008479//queuine tRNA-ribosyltransferase activity,-
81892,0,0,0,0,1,0,0,0,16,0,0,0,SLIRP;SRA stem-loop interacting RNA binding protein,GO:0036126//sperm flagellum;GO:0030529//ribonucleoprotein complex;GO:0005739//mitochondrion;GO:0001669//acrosomal vesicle;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0000961//negative regulation of mitochondrial RNA catabolic process;GO:0070584//mitochondrion morphogenesis;GO:0007286//spermatid development;GO:0007338//single fertilization;GO:0030317//sperm motility;GO:0006355//regulation of transcription, DNA-templated",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K03102//Dorso-ventral axis formation;K14411//mRNA surveillance pathway
81894,0,0,0,6,0,24,0,0,1,0,3,0,"SLC25A28;solute carrier family 25 (mitochondrial iron transporter), member 28",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055072//iron ion homeostasis;GO:0044281//small molecule metabolic process;GO:0006811//ion transport,-,-
819,0,0,0,4,23,0,44,0,4,85,0,0,CAMLG;calcium modulating ligand,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0001881//receptor recycling;GO:0007165//signal transduction;GO:0006952//defense response;GO:0016032//viral process;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0050839//cell adhesion molecule binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
8192,0,16,0,10,15,3,0,0,3,0,13,0,CLPP;caseinolytic mitochondrial matrix peptidase proteolytic subunit,GO:0009368//endopeptidase Clp complex;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix,GO:0051260//protein homooligomerization;GO:0051603//proteolysis involved in cellular protein catabolic process,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0008233//peptidase activity,K01358//Cell cycle - Caulobacter
81926,0,0,0,0,1,0,0,0,11,0,6,0,ABHD17A;abhydrolase domain containing 17A,GO:0005576//extracellular region;GO:0016020//membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0005515//protein binding,K14541//Arginine and proline metabolism;Metabolic pathways
81928,100,0,0,0,0,0,0,72,49,0,13,0,CABLES2;Cdk5 and Abl enzyme substrate 2,-,GO:0051726//regulation of cell cycle;GO:0045859//regulation of protein kinase activity;GO:0007049//cell cycle;GO:0051301//cell division;GO:0051302//regulation of cell division,GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity,-
81929,0,0,0,4,46,0,17,0,14,0,1,0,SEH1L;SEH1-like (S. cerevisiae),GO:0005635//nuclear envelope;GO:0000777//condensed chromosome kinetochore;GO:0031080//nuclear pore outer ring;GO:0005829//cytosol;GO:0000776//kinetochore,GO:0015758//glucose transport;GO:0015031//protein transport;GO:0055085//transmembrane transport;GO:0051028//mRNA transport;GO:0044281//small molecule metabolic process;GO:0002534//cytokine production involved in inflammatory response;GO:0006999//nuclear pore organization;GO:0007080//mitotic metaphase plate congression;GO:0019221//cytokine-mediated signaling pathway;GO:0000278//mitotic cell cycle;GO:0050830//defense response to Gram-positive bacterium;GO:0010827//regulation of glucose transport;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process;GO:0051315//attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation,-,K14299//RNA transport
8193,0,0,0,10,30,12,17,0,13,0,18,0,"DPF1;D4, zinc and double PHD fingers family 1",GO:0071565//nBAF complex;GO:0005737//cytoplasm,"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development",GO:0008270//zinc ion binding,-
81930,0,0,0,4,0,30,15,0,30,0,0,0,KIF18A;kinesin family member 18A,GO:0005829//cytosol;GO:0005871//kinesin complex;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005901//caveola;GO:0005634//nucleus;GO:0001726//ruffle;GO:0005828//kinetochore microtubule;GO:0005737//cytoplasm,GO:0008152//metabolic process;GO:0015031//protein transport;GO:0000278//mitotic cell cycle;GO:0007596//blood coagulation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007080//mitotic metaphase plate congression;GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0007019//microtubule depolymerization,GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0051010//microtubule plus-end binding;GO:0008017//microtubule binding;GO:0070463//tubulin-dependent ATPase activity;GO:0043130//ubiquitin binding;GO:0005515//protein binding,-
81931,0,0,0,0,2,0,0,0,17,0,0,0,ZNF93;zinc finger protein 93,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
81932,0,0,0,1,0,0,0,0,0,0,0,0,HDHD3;haloacid dehalogenase-like hydrolase domain containing 3,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0005515//protein binding;GO:0016787//hydrolase activity,-
8195,0,0,2,52,80,0,53,0,0,0,0,0,MKKS;McKusick-Kaufman syndrome,GO:0005813//centrosome;GO:0005622//intracellular;GO:0031514//motile cilium;GO:0005829//cytosol,GO:0001947//heart looping;GO:0006457//protein folding;GO:0060027//convergent extension involved in gastrulation;GO:0060296//regulation of cilium beat frequency involved in ciliary motility;GO:0021756//striatum development;GO:0038108//negative regulation of appetite by leptin-mediated signaling pathway;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0042384//cilium assembly;GO:0007286//spermatid development;GO:0014824//artery smooth muscle contraction;GO:0045444//fat cell differentiation;GO:0045776//negative regulation of blood pressure;GO:0045494//photoreceptor cell maintenance;GO:0048854//brain morphogenesis;GO:0007608//sensory perception of smell;GO:0060271//cilium morphogenesis;GO:0010629//negative regulation of gene expression;GO:0007507//heart development;GO:0046907//intracellular transport;GO:0021766//hippocampus development;GO:0051216//cartilage development;GO:0051131//chaperone-mediated protein complex assembly;GO:0008406//gonad development;GO:0035176//social behavior;GO:0021987//cerebral cortex development;GO:0042311//vasodilation;GO:0040018//positive regulation of multicellular organism growth;GO:0051877//pigment granule aggregation in cell center;GO:0032402//melanosome transport;GO:0007601//visual perception;GO:0035058//nonmotile primary cilium assembly;GO:0007368//determination of left/right symmetry,GO:0051082//unfolded protein binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0001103//RNA polymerase II repressing transcription factor binding,-
820,0,0,0,0,0,0,0,0,10,0,0,0,CAMP;cathelicidin antimicrobial peptide,GO:0042995//cell projection;GO:0042581//specific granule;GO:0070062//extracellular vesicular exosome;GO:0005618//cell wall;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0019731//antibacterial humoral response;GO:0042742//defense response to bacterium;GO:0044130//negative regulation of growth of symbiont in host;GO:0045766//positive regulation of angiogenesis;GO:0008284//positive regulation of cell proliferation;GO:0050829//defense response to Gram-negative bacterium;GO:0002227//innate immune response in mucosa;GO:0071347//cellular response to interleukin-1;GO:0071354//cellular response to interleukin-6;GO:0044140//negative regulation of growth of symbiont on or near host surface;GO:0001934//positive regulation of protein phosphorylation;GO:0090382//phagosome maturation;GO:0050830//defense response to Gram-positive bacterium;GO:0051701//interaction with host;GO:0071224//cellular response to peptidoglycan;GO:0071356//cellular response to tumor necrosis factor;GO:0051873//killing by host of symbiont cells;GO:0071222//cellular response to lipopolysaccharide,GO:0005515//protein binding,K13916//Tuberculosis;Salivary secretion
8200,0,0,0,0,0,1,23,0,48,0,0,0,GDF5;growth differentiation factor 5,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0035137//hindlimb morphogenesis;GO:0035136//forelimb morphogenesis;GO:0002062//chondrocyte differentiation;GO:0040007//growth;GO:0043524//negative regulation of neuron apoptotic process;GO:0030326//embryonic limb morphogenesis;GO:0007267//cell-cell signaling;GO:0030198//extracellular matrix organization;GO:0040014//regulation of multicellular organism growth;GO:2001054//negative regulation of mesenchymal cell apoptotic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0050680//negative regulation of epithelial cell proliferation;GO:0032332//positive regulation of chondrocyte differentiation,GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0008083//growth factor activity,K04664//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
8202,0,69,50,53,187,8,0,0,66,0,0,0,NCOA3;nuclear receptor coactivator 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0016573//histone acetylation;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045618//positive regulation of keratinocyte differentiation;GO:0060068//vagina development;GO:0035624//receptor transactivation;GO:0048589//developmental growth;GO:0006351//transcription, DNA-templated;GO:0035264//multicellular organism growth;GO:0060744//mammary gland branching involved in thelarche;GO:0010628//positive regulation of gene expression;GO:2001141//regulation of RNA biosynthetic process;GO:0060713//labyrinthine layer morphogenesis",GO:0005515//protein binding;GO:0050681//androgen receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0004871//signal transducer activity;GO:0004402//histone acetyltransferase activity;GO:0047485//protein N-terminus binding;GO:0035257//nuclear hormone receptor binding;GO:0046983//protein dimerization activity;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0003682//chromatin binding,-
8204,0,1,0,64,161,40,1,0,65,0,1,0,NRIP1;nuclear receptor interacting protein 1,GO:0005634//nucleus;GO:0000118//histone deacetylase complex;GO:0030054//cell junction;GO:0005730//nucleolus,"GO:0001543//ovarian follicle rupture;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0019915//lipid storage;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0042826//histone deacetylase binding;GO:0050681//androgen receptor binding;GO:0030331//estrogen receptor binding;GO:0003714//transcription corepressor activity;GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0005515//protein binding;GO:0035259//glucocorticoid receptor binding;GO:0046965//retinoid X receptor binding,-
8208,0,0,0,0,0,0,0,45,30,0,0,0,"CHAF1B;chromatin assembly factor 1, subunit B (p60)",GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0033186//CAF-1 complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006461//protein complex assembly;GO:0007049//cell cycle;GO:0031497//chromatin assembly;GO:0006355//regulation of transcription, DNA-templated;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0006260//DNA replication",GO:0051082//unfolded protein binding;GO:0042393//histone binding;GO:0003682//chromatin binding,-
8209,119,1,1,22,43,0,0,1,0,1,0,0,C21orf33;chromosome 21 open reading frame 33,GO:0005739//mitochondrion,-,-,-
821,106,144,1,153,436,84,10,0,0,0,0,0,CANX;calnexin,GO:0005789//endoplasmic reticulum membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0005840//ribosome;GO:0030424//axon;GO:0043234//protein complex;GO:0043197//dendritic spine;GO:0043025//neuronal cell body;GO:0042470//melanosome;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0032839//dendrite cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0007568//aging;GO:0061077//chaperone-mediated protein folding;GO:0048488//synaptic vesicle endocytosis;GO:0072583//clathrin-mediated endocytosis;GO:0044267//cellular protein metabolic process;GO:0009306//protein secretion;GO:0006457//protein folding;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0030246//carbohydrate binding;GO:0001948//glycoprotein binding;GO:0005509//calcium ion binding;GO:0051082//unfolded protein binding;GO:0035255//ionotropic glutamate receptor binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0034185//apolipoprotein binding,K08054//Protein processing in endoplasmic reticulum;HTLV-I infection;Phagosome;Antigen processing and presentation
8214,0,0,0,0,0,15,0,0,26,0,0,0,DGCR6;DiGeorge syndrome critical region gene 6,GO:0005634//nucleus;GO:0005578//proteinaceous extracellular matrix,GO:0007155//cell adhesion;GO:0009887//organ morphogenesis,-,-
8216,0,0,0,5,10,15,33,0,14,0,8,0,LZTR1;leucine-zipper-like transcription regulator 1,-,"GO:0006355//regulation of transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity,K14966//Herpes simplex infection
8218,22,0,0,10,1,21,17,0,77,88,0,0,"CLTCL1;clathrin, heavy chain-like 1",GO:0030132//clathrin coat of coated pit;GO:0030130//clathrin coat of trans-Golgi network vesicle;GO:0070062//extracellular vesicular exosome;GO:0030135//coated vesicle;GO:0016020//membrane;GO:0030136//clathrin-coated vesicle;GO:0005802//trans-Golgi network;GO:0005819//spindle;GO:0005905//coated pit,GO:0007165//signal transduction;GO:0007067//mitotic nuclear division;GO:0006886//intracellular protein transport;GO:0009653//anatomical structure morphogenesis;GO:0046326//positive regulation of glucose import;GO:0006898//receptor-mediated endocytosis,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0004871//signal transducer activity,K04646//Lysosome;Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Bacterial invasion of epithelial cells;Huntington's disease;Endocytosis
822,0,75,0,0,25,16,20,0,6,0,2,0,"CAPG;capping protein (actin filament), gelsolin-like",GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0008290//F-actin capping protein complex;GO:0042470//melanosome;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,GO:0006461//protein complex assembly;GO:0030031//cell projection assembly;GO:0051016//barbed-end actin filament capping,GO:0003779//actin binding,-
8220,57,401,1505,198,93,25,189,1056,115,0,457,598,DGCR14;DiGeorge syndrome critical region gene 14,GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus,"GO:0007399//nervous system development;GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding,-
8224,0,0,0,0,0,21,0,0,0,0,0,0,SYN3;synapsin III,GO:0008021//synaptic vesicle;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction,"GO:0032228//regulation of synaptic transmission, GABAergic;GO:0008152//metabolic process;GO:0007269//neurotransmitter secretion",GO:0005524//ATP binding;GO:0003824//catalytic activity,-
8225,4,0,0,0,13,0,0,0,12,0,4,0,GTPBP6;GTP binding protein 6 (putative),-,-,GO:0046872//metal ion binding;GO:0005525//GTP binding,-
8226,0,0,0,8,12,0,0,0,20,0,27,0,HDHD1;haloacid dehalogenase-like hydrolase domain containing 1,GO:0070062//extracellular vesicular exosome,GO:0009117//nucleotide metabolic process;GO:0016311//dephosphorylation,GO:0046872//metal ion binding;GO:0016791//phosphatase activity,-
8227,31,0,0,0,15,0,0,0,17,0,6,0,AKAP17A;A kinase (PRKA) anchor protein 17A,GO:0016607//nuclear speck;GO:0005681//spliceosomal complex;GO:0005634//nucleus,"GO:0043484//regulation of RNA splicing;GO:0042113//B cell activation;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0007165//signal transduction;GO:0008380//RNA splicing",GO:0051018//protein kinase A binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
8228,0,0,0,4,20,0,0,53,29,0,0,0,PNPLA4;patatin-like phospholipase domain containing 4,-,GO:0016042//lipid catabolic process,GO:0004806//triglyceride lipase activity,K11157//Retinol metabolism
823,87,3,1,12,61,28,0,1,71,0,40,1,"CAPN1;calpain 1, (mu/I) large subunit",GO:0016020//membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0005737//cytoplasm,GO:0022617//extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0032801//receptor catabolic process;GO:0030198//extracellular matrix organization;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,K01367//Apoptosis;Protein processing in endoplasmic reticulum;Alzheimer's disease
8233,0,0,0,0,0,0,0,0,31,0,15,0,"ZRSR2;zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2",GO:0005689//U12-type spliceosomal complex,"GO:0000245//spliceosomal complex assembly;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing",GO:0030628//pre-mRNA 3'-splice site binding;GO:0000166//nucleotide binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K03105//Protein export;K12836//Shigellosis;Spliceosome
8237,0,0,0,1,11,19,47,0,55,0,0,0,USP11;ubiquitin specific peptidase 11,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//ubiquitin-specific protease activity,-
8239,0,20,0,104,373,60,34,14,94,0,6,0,"USP9X;ubiquitin specific peptidase 9, X-linked",GO:0016020//membrane;GO:0005829//cytosol;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0045177//apical part of cell,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030509//BMP signaling pathway;GO:0010467//gene expression;GO:0048675//axon extension;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0021766//hippocampus development;GO:0016579//protein deubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001701//in utero embryonic development;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007059//chromosome segregation;GO:0001764//neuron migration;GO:0007067//mitotic nuclear division;GO:0009791//post-embryonic development;GO:0007292//female gamete generation",GO:0004221//ubiquitin thiolesterase activity;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0070410//co-SMAD binding,-
824,0,1,19,32,31,36,0,0,46,338,1,2,"CAPN2;calpain 2, (m/II) large subunit",GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0030864//cortical actin cytoskeleton;GO:0005634//nucleus;GO:0097038//perinuclear endoplasmic reticulum;GO:0000785//chromatin;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0031143//pseudopodium,GO:0001824//blastocyst development;GO:0016540//protein autoprocessing;GO:0006508//proteolysis;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0001666//response to hypoxia;GO:0007520//myoblast fusion;GO:0071230//cellular response to amino acid stimulus;GO:0051493//regulation of cytoskeleton organization,GO:0008092//cytoskeletal protein binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0005509//calcium ion binding,K03853//Focal adhesion;Alzheimer's disease;Protein processing in endoplasmic reticulum;Apoptosis
8241,0,0,0,6,6,0,0,0,83,123,6,540,RBM10;RNA binding motif protein 10,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0006397//mRNA processing;GO:0008285//negative regulation of cell proliferation;GO:0008380//RNA splicing,GO:0042802//identical protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0008270//zinc ion binding;GO:0032403//protein complex binding,-
8242,0,0,0,27,16,23,3,1,105,0,2,0,KDM5C;lysine (K)-specific demethylase 5C,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0034720//histone H3-K4 demethylation;GO:0055114//oxidation-reduction process","GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0032453//histone demethylase activity (H3-K4 specific)",-
8243,0,71,0,0,13,46,0,0,160,0,1,0,SMC1A;structural maintenance of chromosomes 1A,"GO:0005730//nucleolus;GO:0000794//condensed nuclear chromosome;GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus;GO:0000776//kinetochore;GO:0005694//chromosome;GO:0008280//cohesin core heterodimer;GO:0000777//condensed chromosome kinetochore;GO:0030893//meiotic cohesin complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm","GO:0032876//negative regulation of DNA endoreduplication;GO:0006281//DNA repair;GO:0042770//signal transduction in response to DNA damage;GO:0007093//mitotic cell cycle checkpoint;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0007052//mitotic spindle organization;GO:0000278//mitotic cell cycle;GO:0019827//stem cell maintenance;GO:0000398//mRNA splicing, via spliceosome;GO:0000070//mitotic sister chromatid segregation;GO:0009314//response to radiation;GO:0007126//meiotic nuclear division;GO:0007062//sister chromatid cohesion;GO:0007064//mitotic sister chromatid cohesion",GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003777//microtubule motor activity;GO:0036033//mediator complex binding;GO:0003682//chromatin binding;GO:0005524//ATP binding,K06636//Cell cycle;Cell cycle - yeast;Meiosis - yeast;Oocyte meiosis
825,0,0,30,0,0,0,14,4,15,0,0,0,"CAPN3;calpain 3, (p94)",GO:0005622//intracellular;GO:0005829//cytosol;GO:0005634//nucleus;GO:0030016//myofibril;GO:0005886//plasma membrane;GO:0030315//T-tubule;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0043234//protein complex,"GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045862//positive regulation of proteolysis;GO:0046716//muscle cell cellular homeostasis;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0045214//sarcomere organization;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0014850//response to muscle activity;GO:0072657//protein localization to membrane;GO:0001896//autolysis;GO:0007517//muscle organ development;GO:0061061//muscle structure development;GO:0051592//response to calcium ion;GO:0071472//cellular response to salt stress;GO:0006508//proteolysis;GO:0045661//regulation of myoblast differentiation;GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0030239//myofibril assembly;GO:0097264//self proteolysis;GO:0006461//protein complex assembly;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0071277//cellular response to calcium ion;GO:0014718//positive regulation of satellite cell activation involved in skeletal muscle regeneration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0033234//negative regulation of protein sumoylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity",GO:0008233//peptidase activity;GO:0031402//sodium ion binding;GO:0008307//structural constituent of muscle;GO:0008234//cysteine-type peptidase activity;GO:0004871//signal transducer activity;GO:0055103//ligase regulator activity;GO:0031432//titin binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0003824//catalytic activity;GO:0032947//protein complex scaffold;GO:0005515//protein binding;GO:0005509//calcium ion binding,-
826,0,27,1,20,134,0,4,0,0,0,0,0,"CAPNS1;calpain, small subunit 1",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0008284//positive regulation of cell proliferation;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,-
8260,0,0,1,0,14,0,0,0,0,0,18,0,"NAA10;N(alpha)-acetyltransferase 10, NatA catalytic subunit",GO:0031415//NatA complex;GO:0005622//intracellular;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006474//N-terminal protein amino acid acetylation;GO:0006475//internal protein amino acid acetylation;GO:0006323//DNA packaging,GO:0008080//N-acetyltransferase activity;GO:0043022//ribosome binding;GO:0004596//peptide alpha-N-acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0005515//protein binding,K01787//Amino sugar and nucleotide sugar metabolism
8266,0,0,0,7,1,0,22,0,25,137,0,0,UBL4A;ubiquitin-like 4A,GO:0005829//cytosol;GO:0071818//BAT3 complex,GO:0071816//tail-anchored membrane protein insertion into ER membrane;GO:0006810//transport;GO:0006464//cellular protein modification process,GO:0005515//protein binding;GO:0019787//small conjugating protein ligase activity,K02927//Ribosome;K02977//Ribosome
8269,0,0,0,0,0,5,0,0,0,41,9,0,TMEM187;transmembrane protein 187,GO:0016021//integral component of membrane;GO:0030133//transport vesicle,-,-,-
827,0,0,0,0,0,0,0,0,39,0,0,73,CAPN6;calpain 6,GO:0005876//spindle microtubule;GO:0048471//perinuclear region of cytoplasm,GO:0051493//regulation of cytoskeleton organization;GO:0001578//microtubule bundle formation;GO:0006508//proteolysis,GO:0008017//microtubule binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,-
8270,0,0,0,0,0,28,0,0,6,0,4,0,"LAGE3;L antigen family, member 3",GO:0005634//nucleus,GO:0008033//tRNA processing,-,-
8273,0,0,0,0,0,0,10,0,0,21,0,0,"SLC10A3;solute carrier family 10, member 3",GO:0016021//integral component of membrane,GO:0015721//bile acid and bile salt transport;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0032526//response to retinoic acid,GO:0008508//bile acid:sodium symporter activity,-
8277,0,0,0,0,10,8,0,0,20,0,0,0,TKTL1;transketolase-like 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006772//thiamine metabolic process;GO:0006007//glucose catabolic process,GO:0046872//metal ion binding;GO:0004802//transketolase activity,K00615//Metabolic pathways;Pentose phosphate pathway;Biosynthesis of ansamycins;RNA degradation;Salmonella infection;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites
828,0,1,0,11,9,0,1,2,16,37,0,2,CAPS;calcyphosine,GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0035556//intracellular signal transduction,GO:0005509//calcium ion binding,K02183//Calcium signaling pathway;Olfactory transduction;Salivary secretion;Alzheimer's disease;Neurotrophin signaling pathway;Glioma;Gastric acid secretion;Melanogenesis;Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system;Phototransduction;Insulin signaling pathway;Tuberculosis;Pertussis;Alcoholism;Long-term potentiation;Amphetamine addiction;Oocyte meiosis;Vascular smooth muscle contraction;Phototransduction - fly;Plant-pathogen interaction;K12042//Calcium signaling pathway
8284,0,1,0,1,40,0,0,0,0,0,0,0,KDM5D;lysine (K)-specific demethylase 5D,GO:0005634//nucleus,GO:0034720//histone H3-K4 demethylation;GO:0055114//oxidation-reduction process,"GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0032453//histone demethylase activity (H3-K4 specific);GO:0016706//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors",-
8287,0,0,1,23,157,0,0,0,0,0,0,0,"USP9Y;ubiquitin specific peptidase 9, Y-linked",GO:0005737//cytoplasm,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030509//BMP signaling pathway;GO:0016579//protein deubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007283//spermatogenesis,GO:0070410//co-SMAD binding;GO:0008234//cysteine-type peptidase activity;GO:0004843//ubiquitin-specific protease activity,-
8288,0,0,0,17,34,12,21,0,33,0,16,0,EPX;eosinophil peroxidase,GO:0070062//extracellular vesicular exosome,GO:0032714//negative regulation of interleukin-5 production;GO:0032753//positive regulation of interleukin-4 production;GO:0072677//eosinophil migration;GO:0055114//oxidation-reduction process;GO:0042744//hydrogen peroxide catabolic process;GO:0032693//negative regulation of interleukin-10 production;GO:0002215//defense response to nematode,GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0004601//peroxidase activity,K10788//Asthma
8289,0,34,24,17,41,0,0,157,29,5,16,0,ARID1A;AT rich interactive domain 1A (SWI-like),GO:0071565//nBAF complex;GO:0005730//nucleolus;GO:0071564//npBAF complex;GO:0005634//nucleus;GO:0016514//SWI/SNF complex;GO:0000790//nuclear chromatin,"GO:0006351//transcription, DNA-templated;GO:0003408//optic cup formation involved in camera-type eye development;GO:0030520//intracellular estrogen receptor signaling pathway;GO:0048096//chromatin-mediated maintenance of transcription;GO:0003205//cardiac chamber development;GO:0030900//forebrain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0042766//nucleosome mobilization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006337//nucleosome disassembly;GO:0043044//ATP-dependent chromatin remodeling;GO:0060674//placenta blood vessel development;GO:0006338//chromatin remodeling;GO:0042921//glucocorticoid receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001843//neural tube closure",GO:0005515//protein binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003677//DNA binding;GO:0031491//nucleosome binding;GO:0003713//transcription coactivator activity,-
829,0,55,2,74,177,0,0,0,46,0,0,0,"CAPZA1;capping protein (actin filament) muscle Z-line, alpha 1",GO:0008290//F-actin capping protein complex;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0071203//WASH complex,GO:0030036//actin cytoskeleton organization;GO:0045087//innate immune response;GO:0006461//protein complex assembly;GO:0007596//blood coagulation;GO:0051693//actin filament capping;GO:0006928//cellular component movement,GO:0003779//actin binding;GO:0005515//protein binding,-
8291,0,14,0,0,0,42,15,62,114,286,20,286,DYSF;dysferlin,GO:0042383//sarcolemma;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0030315//T-tubule;GO:0030027//lamellipodium,GO:0001778//plasma membrane repair;GO:0006906//vesicle fusion,GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,K05857//Calcium signaling pathway;Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways;K02677//Aldosterone-regulated sodium reabsorption;Pancreatic secretion;African trypanosomiasis;Long-term potentiation;Carbohydrate digestion and absorption;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Phototransduction - fly;Amoebiasis;Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Vascular smooth muscle contraction;Wnt signaling pathway;B cell receptor signaling pathway;Salivary secretion;GABAergic synapse;Tight junction;Cholinergic synapse;Fc epsilon RI signaling pathway;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;Serotonergic synapse;Influenza A;Pathways in cancer;Chemokine signaling pathway;GnRH signaling pathway;Dopaminergic synapse;Gap junction;NF-kappa B signaling pathway;ErbB signaling pathway;MAPK signaling pathway;Morphine addiction;Calcium signaling pathway;Retrograde endocannabinoid signaling;Endocrine and other factor-regulated calcium reabsorption;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Long-term depression;Glioma;Pathogenic Escherichia coli infection;Gastric acid secretion;VEGF signaling pathway;Focal adhesion;Leishmaniasis
8292,0,0,0,0,0,2,0,0,7,0,12,0,COLQ;collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase,GO:0005581//collagen trimer;GO:0030054//cell junction;GO:0045202//synapse;GO:0005615//extracellular space;GO:0005605//basal lamina,GO:0008105//asymmetric protein localization;GO:0001507//acetylcholine catabolic process in synaptic cleft,GO:0005515//protein binding,K06237//Focal adhesion;Small cell lung cancer;Protein digestion and absorption;Amoebiasis;ECM-receptor interaction;Pathways in cancer;K06236//Amoebiasis;Protein digestion and absorption;Focal adhesion;ECM-receptor interaction
8295,0,1,1,7,95,40,75,54,173,1,27,0,TRRAP;transformation/transcription domain-associated protein,GO:0033276//transcription factor TFTC complex;GO:0030914//STAGA complex;GO:0000125//PCAF complex;GO:0005654//nucleoplasm;GO:0000812//Swr1 complex;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0007093//mitotic cell cycle checkpoint;GO:0043967//histone H4 acetylation;GO:0016578//histone deubiquitination;GO:0006325//chromatin organization;GO:0043968//histone H2A acetylation;GO:0006351//transcription, DNA-templated","GO:0003713//transcription coactivator activity;GO:0003712//transcription cofactor activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0005515//protein binding",K08874//HTLV-I infection
830,0,90,1,22,235,4,0,0,8,0,0,0,"CAPZA2;capping protein (actin filament) muscle Z-line, alpha 2",GO:0030863//cortical cytoskeleton;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0071203//WASH complex;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0008290//F-actin capping protein complex,GO:0007596//blood coagulation;GO:0051693//actin filament capping;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0030036//actin cytoskeleton organization;GO:0006928//cellular component movement,GO:0003779//actin binding,-
8301,26,51,1,53,180,11,34,0,35,0,0,0,PICALM;phosphatidylinositol binding clathrin assembly protein,GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0042734//presynaptic membrane;GO:0005794//Golgi apparatus;GO:0005905//coated pit;GO:0031982//vesicle;GO:0043025//neuronal cell body;GO:0043231//intracellular membrane-bounded organelle;GO:0097418//neurofibrillary tangle;GO:0030122//AP-2 adaptor complex;GO:0030132//clathrin coat of coated pit;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:1902961//positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process;GO:0007409//axonogenesis;GO:0035459//cargo loading into vesicle;GO:1902963//negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process;GO:0006461//protein complex assembly;GO:0032880//regulation of protein localization;GO:0016192//vesicle-mediated transport;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010629//negative regulation of gene expression;GO:0048261//negative regulation of receptor-mediated endocytosis;GO:0048268//clathrin coat assembly;GO:0072583//clathrin-mediated endocytosis;GO:0055072//iron ion homeostasis;GO:0008283//cell proliferation;GO:0016188//synaptic vesicle maturation;GO:0030100//regulation of endocytosis;GO:0048813//dendrite morphogenesis;GO:0097459//iron ion import into cell;GO:0031623//receptor internalization;GO:1901216//positive regulation of neuron death;GO:0016197//endosomal transport;GO:0006898//receptor-mediated endocytosis;GO:1902004//positive regulation of beta-amyloid formation;GO:0030097//hemopoiesis",GO:0032050//clathrin heavy chain binding;GO:0005515//protein binding;GO:0005545//1-phosphatidylinositol binding;GO:0030276//clathrin binding;GO:0035615//clathrin adaptor activity,-
8302,0,0,0,0,0,0,0,0,0,0,3,0,"KLRC4;killer cell lectin-like receptor subfamily C, member 4",GO:0016021//integral component of membrane,GO:0006968//cellular defense response,-,K06541//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease
8303,0,0,0,17,5,0,0,0,28,0,0,17,SNN;stannin,GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane,GO:0006950//response to stress;GO:0009628//response to abiotic stimulus,-,-
8309,0,0,0,3,0,2,0,0,13,0,5,0,"ACOX2;acyl-CoA oxidase 2, branched chain",GO:0005782//peroxisomal matrix;GO:0005777//peroxisome,GO:0044281//small molecule metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase,"GO:0005102//receptor binding;GO:0050660//flavin adenine dinucleotide binding;GO:0016402//pristanoyl-CoA oxidase activity;GO:0003995//acyl-CoA dehydrogenase activity;GO:0033791//3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity;GO:0003997//acyl-CoA oxidase activity",K10214//Primary bile acid biosynthesis;Metabolic pathways;PPAR signaling pathway;Peroxisome
831,0,9,43,18,177,15,14,0,72,0,0,0,CAST;calpastatin,GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:2000675//negative regulation of type B pancreatic cell apoptotic process;GO:0010951//negative regulation of endopeptidase activity,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity,-
8310,0,1,0,0,17,0,18,0,0,25,0,0,"ACOX3;acyl-CoA oxidase 3, pristanoyl",GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005777//peroxisome;GO:0005782//peroxisomal matrix,GO:0044281//small molecule metabolic process;GO:0033540//fatty acid beta-oxidation using acyl-CoA oxidase;GO:0044255//cellular lipid metabolic process,GO:0050660//flavin adenine dinucleotide binding;GO:0005102//receptor binding;GO:0016402//pristanoyl-CoA oxidase activity;GO:0003995//acyl-CoA dehydrogenase activity,"K00232//beta-Alanine metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Propanoate metabolism;Fatty acid metabolism;Biosynthesis of unsaturated fatty acids;PPAR signaling pathway;Peroxisome;alpha-Linolenic acid metabolism"
8312,0,0,4,0,1,0,0,0,101,0,6,0,AXIN1;axin 1,GO:0005794//Golgi apparatus;GO:0030877//beta-catenin destruction complex;GO:0005881//cytoplasmic microtubule;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005938//cell cortex;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0016328//lateral plasma membrane;GO:0014069//postsynaptic density;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0071944//cell periphery;GO:0005634//nucleus,"GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0051443//positive regulation of ubiquitin-protein transferase activity;GO:0031122//cytoplasmic microtubule organization;GO:0045599//negative regulation of fat cell differentiation;GO:0030910//olfactory placode formation;GO:0060070//canonical Wnt signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0051260//protein homooligomerization;GO:0007605//sensory perception of sound;GO:0001701//in utero embryonic development;GO:0008219//cell death;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0009950//dorsal/ventral axis specification;GO:0006915//apoptotic process;GO:0048320//axial mesoderm formation;GO:0060823//canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0051248//negative regulation of protein metabolic process;GO:0007257//activation of JUN kinase activity;GO:0001743//optic placode formation;GO:0030178//negative regulation of Wnt signaling pathway;GO:0071514//genetic imprinting;GO:0043623//cellular protein complex assembly;GO:0046330//positive regulation of JNK cascade;GO:0071407//cellular response to organic cyclic compound;GO:0032147//activation of protein kinase activity;GO:0000209//protein polyubiquitination;GO:0060272//embryonic skeletal joint morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0036342//post-anal tail morphogenesis;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0035412//regulation of catenin import into nucleus;GO:0021797//forebrain anterior/posterior pattern specification;GO:0021881//Wnt-activated signaling pathway involved in forebrain neuron fate commitment;GO:0048048//embryonic eye morphogenesis;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0007368//determination of left/right symmetry;GO:0055001//muscle cell development;GO:0030163//protein catabolic process;GO:0031398//positive regulation of protein ubiquitination;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006913//nucleocytoplasmic transport",GO:0002039//p53 binding;GO:0031625//ubiquitin protein ligase binding;GO:0070016//armadillo repeat domain binding;GO:0070411//I-SMAD binding;GO:0008013//beta-catenin binding;GO:0046332//SMAD binding;GO:0043621//protein self-association;GO:0042803//protein homodimerization activity;GO:0032947//protein complex scaffold;GO:0005102//receptor binding;GO:0004871//signal transducer activity;GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0070412//R-SMAD binding;GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0005096//GTPase activator activity,K02157//Basal cell carcinoma;Colorectal cancer;Endometrial cancer;Pathways in cancer;Wnt signaling pathway
8313,0,0,0,8,26,11,0,0,21,0,0,0,AXIN2;axin 2,GO:0005634//nucleus;GO:0014069//postsynaptic density;GO:0005938//cell cortex;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0030877//beta-catenin destruction complex;GO:0005881//cytoplasmic microtubule,GO:0042476//odontogenesis;GO:0048255//mRNA stabilization;GO:0090244//Wnt signaling pathway involved in somitogenesis;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0003139//secondary heart field specification;GO:0032423//regulation of mismatch repair;GO:0045668//negative regulation of osteoblast differentiation;GO:0043570//maintenance of DNA repeat elements;GO:0034613//cellular protein localization;GO:0061181//regulation of chondrocyte development;GO:0009950//dorsal/ventral axis specification;GO:0030282//bone mineralization;GO:0001934//positive regulation of protein phosphorylation;GO:0010718//positive regulation of epithelial to mesenchymal transition;GO:0003413//chondrocyte differentiation involved in endochondral bone morphogenesis;GO:0043547//positive regulation of GTPase activity;GO:0070602//regulation of centromeric sister chromatid cohesion;GO:0001957//intramembranous ossification;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0010942//positive regulation of cell death;GO:0008283//cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0071407//cellular response to organic cyclic compound;GO:0035414//negative regulation of catenin import into nucleus,GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding;GO:0019899//enzyme binding;GO:0008013//beta-catenin binding;GO:0070411//I-SMAD binding;GO:0070016//armadillo repeat domain binding;GO:0005515//protein binding;GO:0005096//GTPase activator activity,K04385//Basal cell carcinoma;Colorectal cancer;Endometrial cancer;Pathways in cancer;Wnt signaling pathway
8314,0,0,26,0,21,29,0,56,40,0,15,0,BAP1;BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase),GO:0035517//PR-DUB complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0071108//protein K48-linked deubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0035520//monoubiquitinated protein deubiquitination;GO:0051726//regulation of cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0001558//regulation of cell growth;GO:0006464//cellular protein modification process;GO:0016579//protein deubiquitination;GO:0035522//monoubiquitinated histone H2A deubiquitination,GO:0004221//ubiquitin thiolesterase activity;GO:0008233//peptidase activity;GO:0003682//chromatin binding;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,-
8315,94,0,0,20,19,28,0,0,105,0,4,0,BRAP;BRCA1 associated protein,GO:0000151//ubiquitin ligase complex;GO:0031965//nuclear membrane;GO:0005737//cytoplasm,GO:0007265//Ras protein signal transduction;GO:0016567//protein ubiquitination;GO:0009968//negative regulation of signal transduction;GO:0000165//MAPK cascade,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0000166//nucleotide binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008139//nuclear localization sequence binding,-
8317,0,0,0,0,0,11,0,0,19,0,0,0,CDC7;cell division cycle 7,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0000082//G1/S transition of mitotic cell cycle;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0051301//cell division;GO:0008284//positive regulation of cell proliferation;GO:0044770//cell cycle phase transition;GO:0010571//positive regulation of nuclear cell cycle DNA replication;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation,GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K02214//Meiosis - yeast;Cell cycle - yeast;Cell cycle
8318,8,0,0,0,0,8,0,0,70,0,1,0,CDC45;cell division cycle 45,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005654//nucleoplasm,GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000076//DNA replication checkpoint;GO:0006270//DNA replication initiation;GO:0006271//DNA strand elongation involved in DNA replication,GO:0005515//protein binding,K06628//Cell cycle - yeast;Cell cycle;Meiosis - yeast
832,0,169,3,75,227,25,0,103,22,0,10,0,"CAPZB;capping protein (actin filament) muscle Z-line, beta",GO:0001669//acrosomal vesicle;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0030863//cortical cytoskeleton;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0014704//intercalated disc;GO:0071203//WASH complex;GO:0030018//Z disc;GO:0030027//lamellipodium;GO:0008290//F-actin capping protein complex;GO:0005856//cytoskeleton,GO:0051016//barbed-end actin filament capping;GO:0030036//actin cytoskeleton organization;GO:0007596//blood coagulation;GO:0030032//lamellipodium assembly;GO:0007010//cytoskeleton organization;GO:0090036//regulation of protein kinase C signaling;GO:0031115//negative regulation of microtubule polymerization;GO:0006928//cellular component movement;GO:0048747//muscle fiber development;GO:0022604//regulation of cell morphogenesis;GO:0031175//neuron projection development,GO:0003779//actin binding;GO:0048487//beta-tubulin binding;GO:0051015//actin filament binding,-
8320,0,0,0,0,0,38,0,0,17,0,0,0,EOMES;eomesodermin,GO:0005634//nucleus,"GO:0019827//stem cell maintenance;GO:0032609//interferon-gamma production;GO:0021772//olfactory bulb development;GO:0045597//positive regulation of cell differentiation;GO:0001714//endodermal cell fate specification;GO:0001829//trophectodermal cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007420//brain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0021895//cerebral cortex neuron differentiation;GO:0021796//cerebral cortex regionalization;GO:0001706//endoderm formation;GO:0006351//transcription, DNA-templated;GO:0002302//CD8-positive, alpha-beta T cell differentiation involved in immune response;GO:0060809//mesodermal to mesenchymal transition involved in gastrulation;GO:0001707//mesoderm formation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0010002//cardioblast differentiation;GO:0045664//regulation of neuron differentiation;GO:0035914//skeletal muscle cell differentiation",GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0003682//chromatin binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003677//DNA binding,-
8321,1,0,0,0,42,40,0,0,25,0,23,270,FZD1;frizzled class receptor 1,GO:0005737//cytoplasm;GO:0045177//apical part of cell;GO:0032589//neuron projection membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,"GO:0001934//positive regulation of protein phosphorylation;GO:0030855//epithelial cell differentiation;GO:0001944//vasculature development;GO:0030182//neuron differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0008406//gonad development;GO:0044339//canonical Wnt signaling pathway involved in osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060022//hard palate development;GO:0030514//negative regulation of BMP signaling pathway;GO:0003149//membranous septum morphogenesis;GO:0003151//outflow tract morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0007420//brain development;GO:0035414//negative regulation of catenin import into nucleus;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0044338//canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:0007409//axonogenesis;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0003150//muscular septum morphogenesis;GO:0048286//lung alveolus development;GO:0042493//response to drug;GO:0035425//autocrine signaling;GO:0007267//cell-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated",GO:0005515//protein binding;GO:0017147//Wnt-protein binding;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity;GO:0005109//frizzled binding;GO:0004930//G-protein coupled receptor activity;GO:0005102//receptor binding,K02432//Pathways in cancer;Wnt signaling pathway;HTLV-I infection;Basal cell carcinoma;Melanogenesis
8322,120,11,1,72,122,0,24,0,19,46,44,315,FZD4;frizzled class receptor 4,GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0042995//cell projection,"GO:0016055//Wnt signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0061304//retinal blood vessel morphogenesis;GO:0071300//cellular response to retinoic acid;GO:0043507//positive regulation of JUN kinase activity;GO:0061301//cerebellum vasculature morphogenesis;GO:0030182//neuron differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0010812//negative regulation of cell-substrate adhesion;GO:0035426//extracellular matrix-cell signaling;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007605//sensory perception of sound;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0001570//vasculogenesis;GO:0060070//canonical Wnt signaling pathway;GO:0031987//locomotion involved in locomotory behavior;GO:0030947//regulation of vascular endothelial growth factor receptor signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042701//progesterone secretion;GO:0007420//brain development",GO:0031625//ubiquitin protein ligase binding;GO:0017147//Wnt-protein binding;GO:0019955//cytokine binding;GO:0042813//Wnt-activated receptor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0004930//G-protein coupled receptor activity;GO:0030165//PDZ domain binding,K02354//Pathways in cancer;HTLV-I infection;Wnt signaling pathway;Basal cell carcinoma;Melanogenesis
8323,0,59,31,40,52,17,0,0,34,181,19,415,FZD6;frizzled class receptor 6,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell;GO:0032589//neuron projection membrane;GO:0016327//apicolateral plasma membrane;GO:0005737//cytoplasm,"GO:0033278//cell proliferation in midbrain;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001942//hair follicle development;GO:0042472//inner ear morphogenesis;GO:0007409//axonogenesis;GO:0001843//neural tube closure;GO:0001525//angiogenesis;GO:0030168//platelet activation;GO:0001736//establishment of planar polarity;GO:0008406//gonad development;GO:0035567//non-canonical Wnt signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0035880//embryonic nail plate morphogenesis;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger",GO:0031625//ubiquitin protein ligase binding;GO:0017147//Wnt-protein binding;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity;GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity,K02376//Wnt signaling pathway;HTLV-I infection;Pathways in cancer;Melanogenesis;Basal cell carcinoma
8324,0,0,0,0,0,0,49,0,30,0,10,0,FZD7;frizzled class receptor 7,GO:0045177//apical part of cell;GO:0032589//neuron projection membrane;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,"GO:0007199//G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:0007420//brain development;GO:0046330//positive regulation of JNK cascade;GO:0060231//mesenchymal to epithelial transition;GO:0060070//canonical Wnt signaling pathway;GO:0038031//non-canonical Wnt signaling pathway via JNK cascade;GO:0007409//axonogenesis;GO:0007223//Wnt signaling pathway, calcium modulating pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0042327//positive regulation of phosphorylation;GO:0014834//skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035412//regulation of catenin import into nucleus;GO:0019827//stem cell maintenance;GO:0001944//vasculature development;GO:0033077//T cell differentiation in thymus;GO:0010812//negative regulation of cell-substrate adhesion;GO:0008406//gonad development;GO:0030182//neuron differentiation;GO:0060054//positive regulation of epithelial cell proliferation involved in wound healing;GO:0071300//cellular response to retinoic acid;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042666//negative regulation of ectodermal cell fate specification;GO:0048103//somatic stem cell division",GO:0030165//PDZ domain binding;GO:0042813//Wnt-activated receptor activity;GO:0005109//frizzled binding;GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding;GO:0017147//Wnt-protein binding,K02432//HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Melanogenesis;Basal cell carcinoma
8325,0,0,0,0,0,0,0,0,0,39,0,0,FZD8;frizzled class receptor 8,GO:0042995//cell projection;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane,GO:0007409//axonogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007420//brain development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007186//G-protein coupled receptor signaling pathway;GO:0033077//T cell differentiation in thymus;GO:0001944//vasculature development;GO:0030182//neuron differentiation;GO:0008406//gonad development;GO:0043507//positive regulation of JUN kinase activity;GO:0060070//canonical Wnt signaling pathway,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0017147//Wnt-protein binding;GO:0004930//G-protein coupled receptor activity;GO:0005102//receptor binding;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding,K02375//Melanogenesis;Basal cell carcinoma;Wnt signaling pathway;HTLV-I infection;Pathways in cancer
8326,86,0,0,0,0,0,1,0,31,0,0,0,FZD9;frizzled class receptor 9,GO:0005886//plasma membrane;GO:0031527//filopodium membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,GO:0001944//vasculature development;GO:0007399//nervous system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007420//brain development;GO:0060070//canonical Wnt signaling pathway;GO:0008406//gonad development;GO:0007611//learning or memory;GO:0030183//B cell differentiation;GO:0007405//neuroblast proliferation,GO:0004930//G-protein coupled receptor activity;GO:0042813//Wnt-activated receptor activity;GO:0030165//PDZ domain binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0017147//Wnt-protein binding,K02842//HTLV-I infection;Wnt signaling pathway;Pathways in cancer;Melanogenesis;Basal cell carcinoma
8328,62,0,0,0,0,0,0,0,46,0,0,0,GFI1B;growth factor independent 1B transcription repressor,GO:0005667//transcription factor complex;GO:0016363//nuclear matrix;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051572//negative regulation of histone H3-K4 methylation;GO:0007275//multicellular organismal development;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0045646//regulation of erythrocyte differentiation;GO:0016568//chromatin modification;GO:0051574//positive regulation of histone H3-K9 methylation;GO:0030854//positive regulation of granulocyte differentiation,GO:0003677//DNA binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
833,0,16,51,0,40,12,0,0,24,0,3,0,CARS;cysteinyl-tRNA synthetase,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0006423//cysteinyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0010467//gene expression,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005524//ATP binding;GO:0000049//tRNA binding;GO:0004817//cysteine-tRNA ligase activity,K01883//Ribosome;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;DNA replication
8330,0,36,0,0,0,0,0,0,0,0,0,0,"HIST1H2AK;histone cluster 1, H2ak",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11251//Systemic lupus erythematosus;Alcoholism
8331,0,0,0,0,0,0,0,0,1,0,0,0,"HIST1H2AJ;histone cluster 1, H2aj",-,-,-,K11251//Alcoholism;Systemic lupus erythematosus
8332,0,32,0,0,0,0,0,0,0,0,13,0,"HIST1H2AL;histone cluster 1, H2al",-,-,-,K11251//Systemic lupus erythematosus;Alcoholism
8334,0,0,0,10,14,0,0,0,0,0,0,0,"HIST1H2AC;histone cluster 1, H2ac",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,-,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11251//Systemic lupus erythematosus;Alcoholism
8336,0,0,0,0,0,0,0,0,29,0,0,0,"HIST1H2AM;histone cluster 1, H2am",-,-,-,K11251//Systemic lupus erythematosus;Alcoholism
8338,73,41,0,0,1,0,0,0,0,0,15,0,"HIST2H2AC;histone cluster 2, H2ac",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Systemic lupus erythematosus;Alcoholism
8339,180,0,0,18,1,0,0,0,11,0,0,0,"HIST1H2BG;histone cluster 1, H2bg",-,-,-,K11252//Systemic lupus erythematosus;Alcoholism
83394,0,0,0,0,1,15,42,0,99,109,26,0,PITPNM3;PITPNM family member 3,GO:0016021//integral component of membrane;GO:0012505//endomembrane system;GO:0005622//intracellular,GO:0046488//phosphatidylinositol metabolic process;GO:0015914//phospholipid transport,GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0030971//receptor tyrosine kinase binding;GO:0008526//phosphatidylinositol transporter activity;GO:0008289//lipid binding,-
834,0,25,0,0,17,0,31,0,3,0,9,0,"CASP1;caspase 1, apoptosis-related cysteine peptidase",GO:0097169//AIM2 inflammasome complex;GO:0072557//IPAF inflammasome complex;GO:0005737//cytoplasm;GO:0072559//NLRP3 inflammasome complex;GO:0072558//NLRP1 inflammasome complex;GO:0005829//cytosol;GO:0005576//extracellular region,"GO:0050727//regulation of inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0071310//cellular response to organic substance;GO:0060081//membrane hyperpolarization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097194//execution phase of apoptosis;GO:0045087//innate immune response;GO:0032611//interleukin-1 beta production;GO:0070269//pyroptosis;GO:0033198//response to ATP;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0097300//programmed necrotic cell death;GO:0006508//proteolysis;GO:0071260//cellular response to mechanical stimulus;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0050717//positive regulation of interleukin-1 alpha secretion;GO:0051882//mitochondrial depolarization;GO:0007165//signal transduction",GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process,K01370//Pertussis;Legionellosis;Influenza A;NOD-like receptor signaling pathway;Salmonella infection;Cytosolic DNA-sensing pathway;Amyotrophic lateral sclerosis (ALS)
8340,0,0,0,0,0,0,0,0,14,0,2,0,"HIST1H2BL;histone cluster 1, H2bl",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome,GO:0006334//nucleosome assembly;GO:0006325//chromatin organization,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Systemic lupus erythematosus;Alcoholism
83401,0,0,0,0,0,0,0,0,12,0,0,0,ELOVL3;ELOVL fatty acid elongase 3,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,"GO:0034625//fatty acid elongation, monounsaturated fatty acid;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0034626//fatty acid elongation, polyunsaturated fatty acid;GO:0044281//small molecule metabolic process;GO:0042761//very long-chain fatty acid biosynthetic process;GO:0019367//fatty acid elongation, saturated fatty acid;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process",GO:0005515//protein binding;GO:0016740//transferase activity,K10248//Fatty acid elongation
8341,0,0,0,0,7,0,0,0,12,0,0,0,"HIST1H2BN;histone cluster 1, H2bn",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0006334//nucleosome assembly,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Alcoholism;Systemic lupus erythematosus
83416,0,12,0,0,0,11,15,0,27,347,0,0,FCRL5;Fc receptor-like 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0043235//receptor complex,GO:0051280//negative regulation of release of sequestered calcium ion into cytosol;GO:0050859//negative regulation of B cell receptor signaling pathway,-,-
83417,0,0,41,0,0,0,0,0,26,0,22,0,FCRL4;Fc receptor-like 4,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0002376//immune system process,GO:0005515//protein binding,-
8342,0,0,0,0,0,0,2,34,0,0,0,0,"HIST1H2BM;histone cluster 1, H2bm",GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0006334//nucleosome assembly,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Systemic lupus erythematosus;Alcoholism
83439,0,0,0,0,0,0,67,143,20,0,0,185,"TCF7L1;transcription factor 7-like 1 (T-cell specific, HMG-box)",GO:0005667//transcription factor complex;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0035019//somatic stem cell maintenance;GO:0048699//generation of neurons;GO:0046022//positive regulation of transcription from RNA polymerase II promoter during mitosis;GO:0008595//anterior/posterior axis specification, embryo;GO:0030111//regulation of Wnt signaling pathway;GO:0007420//brain development;GO:2000036//regulation of stem cell maintenance;GO:0006325//chromatin organization;GO:0048319//axial mesoderm morphogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043588//skin development;GO:0060070//canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0044212//transcription regulatory region DNA binding;GO:0008013//beta-catenin binding,K04490//Adherens junction;Colorectal cancer;Thyroid cancer;Melanogenesis;Endometrial cancer;Wnt signaling pathway;Basal cell carcinoma;Prostate cancer;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Pathways in cancer;Acute myeloid leukemia
8344,0,0,0,0,0,0,0,0,15,0,0,0,"HIST1H2BE;histone cluster 1, H2be",-,-,-,K11252//Alcoholism;Systemic lupus erythematosus
83440,0,0,46,45,8,0,0,174,86,0,86,0,ADPGK;ADP-dependent glucokinase,GO:0005576//extracellular region;GO:0016020//membrane,GO:0016310//phosphorylation;GO:0006096//glycolytic process,GO:0046872//metal ion binding;GO:0043843//ADP-specific glucokinase activity,K08074//Metabolic pathways;Glycolysis / Gluconeogenesis
83442,0,0,0,0,0,0,0,62,11,0,14,0,SH3BGRL3;SH3 domain binding glutamate-rich protein like 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0070062//extracellular vesicular exosome,GO:0032956//regulation of actin cytoskeleton organization;GO:0045454//cell redox homeostasis;GO:0032321//positive regulation of Rho GTPase activity;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0055114//oxidation-reduction process;GO:0030834//regulation of actin filament depolymerization,GO:0015035//protein disulfide oxidoreductase activity;GO:0009055//electron carrier activity;GO:0005100//Rho GTPase activator activity;GO:0030215//semaphorin receptor binding,K01047//GnRH signaling pathway;alpha-Linolenic acid metabolism;Pancreatic secretion;Serotonergic synapse;Vascular smooth muscle contraction;Metabolic pathways;MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Arachidonic acid metabolism;Toxoplasmosis;VEGF signaling pathway;Ether lipid metabolism;Glycerophospholipid metabolism
83443,0,0,1,5,2,0,0,0,0,0,0,0,"SF3B5;splicing factor 3b, subunit 5, 10kDa",GO:0005689//U12-type spliceosomal complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0010467//gene expression;GO:0008380//RNA splicing",-,K12832//Spliceosome
83444,0,0,0,0,9,0,0,0,0,0,0,0,INO80B;INO80 complex subunit B,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031011//Ino80 complex;GO:0005886//plasma membrane;GO:0005730//nucleolus,"GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006310//DNA recombination;GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling",GO:0046872//metal ion binding;GO:0005515//protein binding,-
83445,97,22,0,0,0,20,0,0,23,21,0,0,GSG1;germ cell associated 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,-,GO:0070063//RNA polymerase binding,K04257//Olfactory transduction;K00543//Tryptophan metabolism;Metabolic pathways;K09299//Transcriptional misregulation in cancer
83446,64,0,0,0,0,0,2,0,14,0,0,2,CCDC70;coiled-coil domain containing 70,GO:0005886//plasma membrane;GO:0005576//extracellular region,-,-,-
83447,0,0,0,0,0,18,0,3,28,0,0,0,"SLC25A31;solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31",GO:0005634//nucleus;GO:0031514//motile cilium;GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0055085//transmembrane transport,GO:0005215//transporter activity,K05863//Parkinson's disease;HTLV-I infection;Huntington's disease;Influenza A;Calcium signaling pathway
83448,0,0,27,0,18,0,0,0,59,0,0,0,PUS7L;pseudouridylate synthase 7 homolog (S. cerevisiae)-like,-,GO:0001522//pseudouridine synthesis;GO:0008033//tRNA processing,GO:0003723//RNA binding;GO:0009982//pseudouridine synthase activity,-
83449,39,0,0,0,0,12,22,0,35,0,24,0,PMFBP1;polyamine modulated factor 1 binding protein 1,GO:0005737//cytoplasm,-,-,K12478//Tuberculosis;Endocytosis;Phagosome;K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
83450,0,1,1,43,104,0,0,135,24,0,88,0,LRRC48;leucine rich repeat containing 48,GO:0005737//cytoplasm,-,-,K10411//Huntington's disease
83451,0,0,0,0,0,0,0,0,28,0,0,0,ABHD11;abhydrolase domain containing 11,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
83452,0,1,0,12,40,0,45,48,0,0,37,0,"RAB33B;RAB33B, member RAS oncogene family",GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane,"GO:0015031//protein transport;GO:2000156//regulation of retrograde vesicle-mediated transport, Golgi to ER;GO:2000785//regulation of autophagic vacuole assembly;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0006914//autophagy",GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
83460,0,1,0,0,0,0,0,0,0,0,0,0,EMC6;ER membrane protein complex subunit 6,GO:0072546//ER membrane protein complex;GO:0016021//integral component of membrane,-,-,-
83461,0,0,0,0,0,0,0,0,13,0,0,0,CDCA3;cell division cycle associated 3,GO:0005829//cytosol,GO:0016567//protein ubiquitination;GO:0007067//mitotic nuclear division,-,K07825//Glutamatergic synapse;Taste transduction;Morphine addiction;Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Cholinergic synapse
83463,2,1276,648,1488,1846,17,122,1182,142,456,3412,457,MXD3;MAX dimerization protein 3,GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity,K10082//Protein processing in endoplasmic reticulum
83464,1,0,0,0,4,0,44,0,47,0,8,0,APH1B;APH1B gamma secretase subunit,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0030133//transport vesicle,GO:0007219//Notch signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0016485//protein processing;GO:0031293//membrane protein intracellular domain proteolysis;GO:0007220//Notch receptor processing;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0043085//positive regulation of catalytic activity,GO:0005515//protein binding;GO:0008233//peptidase activity,K06172//Alzheimer's disease;Notch signaling pathway
83468,0,0,0,0,0,0,0,0,31,0,6,0,GLT8D2;glycosyltransferase 8 domain containing 2,GO:0016021//integral component of membrane,GO:0008152//metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups",-
8347,0,0,0,8,6,0,0,0,0,0,0,0,"HIST1H2BC;histone cluster 1, H2bc",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0000786//nucleosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0002227//innate immune response in mucosa;GO:0006325//chromatin organization;GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium;GO:0006334//nucleosome assembly,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Alcoholism;Systemic lupus erythematosus
83473,0,0,0,0,0,0,0,0,27,0,0,0,KATNAL2;katanin p60 subunit A-like 2,GO:0005874//microtubule;GO:0005737//cytoplasm,GO:0006200//ATP catabolic process;GO:0051013//microtubule severing,GO:0008568//microtubule-severing ATPase activity;GO:0008017//microtubule binding;GO:0005524//ATP binding,-
83475,0,1,0,0,0,8,10,0,32,0,0,0,DOHH;deoxyhypusine hydroxylase/monooxygenase,GO:0005829//cytosol,GO:0008612//peptidyl-lysine modification to peptidyl-hypusine;GO:0055114//oxidation-reduction process;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0019135//deoxyhypusine monooxygenase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
83478,0,42,0,0,38,22,15,0,60,0,0,18,ARHGAP24;Rho GTPase activating protein 24,GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005856//cytoskeleton;GO:0042995//cell projection,"GO:1900028//negative regulation of ruffle assembly;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0030154//cell differentiation;GO:0032863//activation of Rac GTPase activity;GO:0035021//negative regulation of Rac protein signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0001525//angiogenesis;GO:0035313//wound healing, spreading of epidermal cells",GO:0005515//protein binding;GO:0030675//Rac GTPase activator activity,K08878//Chronic myeloid leukemia;Pathways in cancer;K07526//Axon guidance
83479,1,0,0,5,28,11,21,0,51,0,0,0,DDX59;DEAD (Asp-Glu-Ala-Asp) box polypeptide 59,GO:0005622//intracellular;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0004386//helicase activity;GO:0046872//metal ion binding;GO:0003723//RNA binding;GO:0005524//ATP binding,K12858//Spliceosome
83480,0,0,0,0,18,0,18,0,12,0,4,0,PUS3;pseudouridylate synthase 3,GO:0005634//nucleus,GO:0031119//tRNA pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0003723//RNA binding,-
83481,0,1,1,0,0,0,1,42,32,0,8,0,EPPK1;epiplakin 1,GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,GO:0044822//poly(A) RNA binding,-
83482,0,0,0,0,0,0,0,0,10,0,17,0,SCRT1;scratch family zinc finger 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:2001222//regulation of neuron migration;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
83483,0,0,0,0,0,21,18,0,16,0,0,0,PLVAP;plasmalemma vesicle associated protein,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005901//caveola;GO:0048471//perinuclear region of cytoplasm,GO:0070528//protein kinase C signaling;GO:0000165//MAPK cascade;GO:0002693//positive regulation of cellular extravasation;GO:0033209//tumor necrosis factor-mediated signaling pathway,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,-
8349,13,45,4,41,295,0,0,0,10,0,0,0,"HIST2H2BE;histone cluster 2, H2be",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space;GO:0000786//nucleosome,GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium;GO:0006334//nucleosome assembly;GO:0002227//innate immune response in mucosa;GO:0006325//chromatin organization,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Systemic lupus erythematosus;Alcoholism
835,0,0,0,7,6,5,0,0,20,4,5,0,"CASP2;caspase 2, apoptosis-related cysteine peptidase",GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0003407//neural retina development;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0097194//execution phase of apoptosis;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0007420//brain development;GO:0001554//luteolysis;GO:0043525//positive regulation of neuron apoptotic process;GO:0007568//aging;GO:0016485//protein processing;GO:0006508//proteolysis;GO:0071260//cellular response to mechanical stimulus;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0035234//ectopic germ cell programmed cell death;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0006915//apoptotic process",GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding,-
8350,0,0,0,0,0,1,0,0,0,0,0,0,"HIST1H3A;histone cluster 1, H3a",-,-,-,K11253//Transcriptional misregulation in cancer;Alcoholism;Systemic lupus erythematosus
8351,0,0,0,1,0,0,0,0,0,0,0,0,"HIST1H3D;histone cluster 1, H3d",-,-,-,K11253//Systemic lupus erythematosus;Alcoholism;Transcriptional misregulation in cancer
83538,0,0,0,0,0,0,0,0,37,0,0,0,TTC25;tetratricopeptide repeat domain 25,GO:0005737//cytoplasm,-,-,K15839//Cocaine addiction;K09553//Prion diseases
83539,0,0,0,4,0,8,0,0,0,0,0,0,CHST9;carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005576//extracellular region,GO:0005975//carbohydrate metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0030166//proteoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0042446//hormone biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process,GO:0001537//N-acetylgalactosamine 4-O-sulfotransferase activity,-
83540,0,0,0,0,9,0,0,0,34,0,15,0,"NUF2;NUF2, NDC80 kinetochore complex component","GO:0031262//Ndc80 complex;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0005829//cytosol;GO:0000775//chromosome, centromeric region;GO:0005634//nucleus",GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation,GO:0005515//protein binding,-
83541,0,0,0,9,22,0,0,6,10,0,0,0,"FAM110A;family with sequence similarity 110, member A",GO:0000922//spindle pole;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm,-,GO:0005515//protein binding,K02947//Ribosome
83543,0,1,0,0,0,0,0,0,0,0,0,0,AIF1L;allograft inflammatory factor 1-like,GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0032587//ruffle membrane;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0005884//actin filament,-,GO:0051015//actin filament binding;GO:0005509//calcium ion binding,-
83544,12,1,0,21,39,41,0,0,68,0,0,2,"DNAL1;dynein, axonemal, light chain 1",-,-,-,K10411//Huntington's disease
83546,0,1,0,0,0,20,0,0,15,0,12,0,RTBDN;retbindin,GO:0005576//extracellular region,-,-,K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K13649//Endocytosis
83547,0,0,0,0,1,0,39,1,21,62,0,0,RILP;Rab interacting lysosomal protein,GO:0005764//lysosome;GO:0043234//protein complex;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005770//late endosome;GO:0005739//mitochondrion;GO:0030670//phagocytic vesicle membrane,GO:0015031//protein transport;GO:0008333//endosome to lysosome transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0017137//Rab GTPase binding;GO:0005515//protein binding,K13883//Phagosome;Salmonella infection
83548,0,3,0,25,76,9,69,0,29,0,21,0,COG3;component of oligomeric golgi complex 3,GO:0005801//cis-Golgi network;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0032580//Golgi cisterna membrane;GO:0017119//Golgi transport complex;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0033365//protein localization to organelle;GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0050821//protein stabilization;GO:0006486//protein glycosylation",GO:0005515//protein binding;GO:0008565//protein transporter activity,-
83549,0,23,49,1,31,29,0,66,1,0,14,0,UCK1;uridine-cytidine kinase 1,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0043097//pyrimidine nucleoside salvage;GO:0006206//pyrimidine nucleobase metabolic process;GO:0016310//phosphorylation;GO:0044211//CTP salvage;GO:0044206//UMP salvage,GO:0005524//ATP binding;GO:0004849//uridine kinase activity;GO:0019206//nucleoside kinase activity,K00876//Drug metabolism - other enzymes;Pyrimidine metabolism;Aminobenzoate degradation;Metabolic pathways;Pyruvate metabolism;Microbial metabolism in diverse environments
83550,0,0,0,0,0,0,0,0,5,0,0,0,GPR101;G protein-coupled receptor 101,GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
83551,0,0,0,0,0,14,0,0,0,0,0,0,TAAR8;trace amine associated receptor 8,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0001594//trace-amine receptor activity,K05051//Neuroactive ligand-receptor interaction
8356,0,0,0,0,0,0,0,0,12,0,0,0,"HIST1H3J;histone cluster 1, H3j",-,-,-,K11253//Alcoholism;Transcriptional misregulation in cancer;Systemic lupus erythematosus
83590,0,0,0,1,0,0,0,0,2,0,0,0,TMUB1;transmembrane and ubiquitin-like domain containing 1,GO:0016021//integral component of membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
83591,0,18,0,0,12,0,0,0,19,0,0,0,"THAP2;THAP domain containing, apoptosis associated protein 2",GO:0005730//nucleolus,-,GO:0003677//DNA binding;GO:0046872//metal ion binding,-
83592,0,0,0,0,0,26,13,0,31,0,13,0,"AKR1E2;aldo-keto reductase family 1, member E2",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process,"GO:0050571//1,5-anhydro-D-fructose reductase activity",-
83593,0,0,0,0,17,0,0,0,8,198,0,0,RASSF5;Ras association (RalGDS/AF-6) domain family member 5,GO:0005874//microtubule;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008285//negative regulation of cell proliferation;GO:0031398//positive regulation of protein ubiquitination;GO:0035556//intracellular signal transduction;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0046872//metal ion binding,K08015//Leukocyte transendothelial migration;Non-small cell lung cancer;Pathways in cancer
83594,0,0,0,4,0,0,0,0,12,0,0,0,NUDT12;nudix (nucleoside diphosphate linked moiety X)-type motif 12,GO:0005634//nucleus;GO:0005777//peroxisome,GO:0006742//NADP catabolic process;GO:0019677//NAD catabolic process,GO:0046872//metal ion binding;GO:0000210//NAD+ diphosphatase activity;GO:0035529//NADH pyrophosphatase activity,K03426//Nicotinate and nicotinamide metabolism;Peroxisome
83595,20,0,26,0,0,0,0,0,16,0,11,0,SOX7;SRY (sex determining region Y)-box 7,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0008285//negative regulation of cell proliferation;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0006351//transcription, DNA-templated;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001706//endoderm formation;GO:0045892//negative regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
83596,203,158,0,69,56,3,0,59,34,0,188,0,BCL2L12;BCL2-like 12 (proline rich),GO:0005634//nucleus;GO:0016020//membrane,GO:1990001//inhibition of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding,-
83597,1,0,0,0,0,0,19,0,13,0,0,655,RTP3;receptor (chemosensory) transporter protein 3,GO:0005737//cytoplasm;GO:0016021//integral component of membrane,GO:0006612//protein targeting to membrane;GO:0001580//detection of chemical stimulus involved in sensory perception of bitter taste,GO:0005515//protein binding,-
836,0,0,0,23,51,9,23,0,16,0,0,0,"CASP3;caspase 3, apoptosis-related cysteine peptidase",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0009611//response to wounding;GO:0030220//platelet formation;GO:1902510//regulation of apoptotic DNA fragmentation;GO:0097190//apoptotic signaling pathway;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0043029//T cell homeostasis;GO:0007507//heart development;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0097194//execution phase of apoptosis;GO:0046007//negative regulation of activated T cell proliferation;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0043066//negative regulation of apoptotic process;GO:0034349//glial cell apoptotic process;GO:0009411//response to UV;GO:0043525//positive regulation of neuron apoptotic process;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006974//cellular response to DNA damage stimulus;GO:0030889//negative regulation of B cell proliferation;GO:0022617//extracellular matrix disassembly;GO:0001836//release of cytochrome c from mitochondria;GO:0042981//regulation of apoptotic process;GO:0035329//hippo signaling;GO:0006508//proteolysis;GO:0006309//apoptotic DNA fragmentation;GO:0043065//positive regulation of apoptotic process;GO:0001782//B cell homeostasis;GO:0006915//apoptotic process;GO:0030216//keratinocyte differentiation;GO:0030182//neuron differentiation;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0034612//response to tumor necrosis factor;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0030198//extracellular matrix organization;GO:0045165//cell fate commitment;GO:0007605//sensory perception of sound;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0030218//erythrocyte differentiation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0051402//neuron apoptotic process,GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0097200//cysteine-type endopeptidase activity involved in execution phase of apoptosis;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0004190//aspartic-type endopeptidase activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0008233//peptidase activity,K02187//Toxoplasmosis;Alzheimer's disease;p53 signaling pathway;Legionellosis;Viral myocarditis;Apoptosis;Natural killer cell mediated cytotoxicity;Herpes simplex infection;MAPK signaling pathway;Amyotrophic lateral sclerosis (ALS);Amoebiasis;Colorectal cancer;Epithelial cell signaling in Helicobacter pylori infection;Pathways in cancer;Parkinson's disease;Huntington's disease;Serotonergic synapse;Tuberculosis;Pertussis
8360,0,0,0,1,0,0,0,0,0,0,1,0,"HIST1H4D;histone cluster 1, H4d",-,-,-,K11254//Alcoholism;Systemic lupus erythematosus
83604,0,0,1,0,25,16,0,67,60,0,0,0,TMEM47;transmembrane protein 47,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005911//cell-cell junction,-,-,K10136//p53 signaling pathway
83605,52,0,0,0,18,0,13,0,10,0,3,0,CCM2;cerebral cavernous malformation 2,GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0035264//multicellular organism growth;GO:0048845//venous blood vessel morphogenesis;GO:0051403//stress-activated MAPK cascade;GO:0001701//in utero embryonic development;GO:0001885//endothelial cell development;GO:0060039//pericardium development;GO:0060837//blood vessel endothelial cell differentiation;GO:0001570//vasculogenesis;GO:0045216//cell-cell junction organization;GO:0048839//inner ear development;GO:0007229//integrin-mediated signaling pathway;GO:0061154//endothelial tube morphogenesis,GO:0005515//protein binding,-
83606,0,42,2,27,109,28,1,110,10,0,11,1,GUCD1;guanylyl cyclase domain containing 1,-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
83607,58,0,0,0,34,4,1,29,33,0,5,0,AMMECR1L;AMMECR1-like,-,-,-,-
8361,0,0,0,0,0,0,0,0,6,0,0,0,"HIST1H4F;histone cluster 1, H4f",-,-,-,K11254//Systemic lupus erythematosus;Alcoholism
8362,0,0,0,0,0,0,0,0,4,0,0,0,"HIST1H4K;histone cluster 1, H4k",-,-,-,K11254//Systemic lupus erythematosus;Alcoholism
83636,0,0,0,9,16,17,18,0,14,101,12,0,C19orf12;chromosome 19 open reading frame 12,GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0008219//cell death,-,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
83637,0,0,0,0,0,0,0,0,0,0,4,0,"ZMIZ2;zinc finger, MIZ-type containing 2",GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0043596//nuclear replication fork;GO:0005730//nucleolus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,K04706//Ubiquitin mediated proteolysis;Hepatitis C;Jak-STAT signaling pathway;K16065//NF-kappa B signaling pathway;Jak-STAT signaling pathway;Ubiquitin mediated proteolysis;K16063//Small cell lung cancer;Ubiquitin mediated proteolysis;Pathways in cancer;Jak-STAT signaling pathway
83638,0,0,0,0,0,0,4,0,2,0,1,0,C11orf68;chromosome 11 open reading frame 68,-,-,GO:0044822//poly(A) RNA binding,-
83639,0,0,0,2,12,16,0,0,13,0,0,0,TEX101;testis expressed 101,GO:0031225//anchored component of membrane;GO:0002080//acrosomal membrane;GO:0005886//plasma membrane,-,-,-
8364,0,1,0,10,0,0,0,0,0,0,0,0,"HIST1H4C;histone cluster 1, H4c",-,-,-,K11254//Alcoholism;Systemic lupus erythematosus
83640,0,0,0,8,19,0,27,0,14,0,0,0,"FAM103A1;family with sequence similarity 103, member A1",GO:0005634//nucleus;GO:0005845//mRNA cap binding complex,GO:0036031//recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex;GO:0006370//7-methylguanosine mRNA capping;GO:0032259//methylation,GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
83641,75,45,1,73,168,21,1,0,22,0,0,0,"FAM107B;family with sequence similarity 107, member B",-,GO:0007605//sensory perception of sound,-,-
83642,0,1,0,0,12,0,0,57,0,0,11,0,SELO;selenoprotein O,-,-,-,-
83643,0,0,0,0,0,17,9,197,39,1,12,1,CCDC3;coiled-coil domain containing 3,GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum,-,-,-
83648,107,0,0,0,14,24,5,56,7,0,0,0,"FAM167A;family with sequence similarity 167, member A",-,-,-,-
8365,0,0,0,0,8,0,0,0,0,0,0,0,"HIST1H4H;histone cluster 1, H4h",-,-,-,K11254//Systemic lupus erythematosus;Alcoholism
83650,0,0,0,0,0,0,0,0,0,0,11,0,"SLC35G5;solute carrier family 35, member G5",GO:0016021//integral component of membrane,-,-,-
83658,0,0,0,0,26,23,0,0,10,0,1,0,"DYNLRB1;dynein, light chain, roadblock-type 1",GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0005868//cytoplasmic dynein complex,GO:0007018//microtubule-based movement;GO:0006810//transport;GO:0008152//metabolic process;GO:0007632//visual behavior,GO:0042802//identical protein binding;GO:0003777//microtubule motor activity,-
83659,0,0,0,0,0,0,0,0,24,145,0,486,TEKT1;tektin 1,GO:0005874//microtubule;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005929//cilium,-,-,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;K04688//mTOR signaling pathway;Acute myeloid leukemia;Insulin signaling pathway;Fc gamma R-mediated phagocytosis;ErbB signaling pathway;TGF-beta signaling pathway
8366,0,1,1,0,0,0,27,0,13,0,0,0,"HIST1H4B;histone cluster 1, H4b",-,-,-,K11254//Alcoholism;Systemic lupus erythematosus
83660,68,0,0,10,0,8,33,7,121,223,20,125,TLN2;talin 2,GO:0015629//actin cytoskeleton;GO:0005925//focal adhesion;GO:0005916//fascia adherens;GO:0001726//ruffle;GO:0045202//synapse;GO:0005886//plasma membrane;GO:0005911//cell-cell junction;GO:0005737//cytoplasm,GO:0007016//cytoskeletal anchoring at plasma membrane;GO:0007155//cell adhesion;GO:0007043//cell-cell junction assembly,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0003779//actin binding;GO:0005200//structural constituent of cytoskeleton;GO:0005158//insulin receptor binding,K06271//HTLV-I infection;Focal adhesion
83661,0,0,0,0,7,0,0,50,0,0,0,0,"MS4A8;membrane-spanning 4-domains, subfamily A, member 8",GO:0016021//integral component of membrane,-,-,K06466//Hematopoietic cell lineage
83666,0,134,49,109,322,39,27,82,94,0,478,483,"PARP9;poly (ADP-ribose) polymerase family, member 9",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0005829//cytosol,GO:0006302//double-strand break repair;GO:0060330//regulation of response to interferon-gamma;GO:0016477//cell migration,GO:0005515//protein binding;GO:0003950//NAD+ ADP-ribosyltransferase activity,-
83667,0,0,0,0,1,0,0,0,23,0,0,0,SESN2;sestrin 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006635//fatty acid beta-oxidation;GO:0006914//autophagy;GO:2000479//regulation of cAMP-dependent protein kinase activity;GO:1901031//regulation of response to reactive oxygen species;GO:0090526//regulation of gluconeogenesis involved in cellular glucose homeostasis;GO:0046323//glucose import;GO:0043491//protein kinase B signaling;GO:0009749//response to glucose;GO:0070328//triglyceride homeostasis;GO:0032868//response to insulin,-,K10141//p53 signaling pathway
8367,0,9,0,4,14,0,0,0,5,0,0,0,"HIST1H4E;histone cluster 1, H4e",-,-,-,K11254//Systemic lupus erythematosus;Alcoholism
8368,0,0,0,0,0,0,0,0,10,0,0,0,"HIST1H4L;histone cluster 1, H4l",-,-,-,K11254//Alcoholism;Systemic lupus erythematosus
83690,170,0,0,0,0,0,12,0,22,0,0,0,CRISPLD1;cysteine-rich secretory protein LCCL domain containing 1,GO:0070062//extracellular vesicular exosome,GO:0060325//face morphogenesis,-,K02330//HTLV-I infection;Base excision repair;K06560//Phagosome;Tuberculosis
83692,0,0,0,6,1,0,0,0,36,0,0,0,CD99L2;CD99 molecule-like 2,GO:0016021//integral component of membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane,GO:0007155//cell adhesion,-,K06520//Cell adhesion molecules (CAMs);Leukocyte transendothelial migration
83693,0,0,0,0,3,1,3,0,25,0,0,0,HSDL1;hydroxysteroid dehydrogenase like 1,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,"K00044//Fatty acid elongation;Metabolic pathways;Steroid hormone biosynthesis;Biosynthesis of unsaturated fatty acids;K10251//Fatty acid elongation;Metabolic pathways;Steroid hormone biosynthesis;Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;K00100//Metabolic pathways;Linoleic acid metabolism;Two-component system;Fructose and mannose metabolism;Naphthalene degradation;Limonene and pinene degradation;Chloroalkane and chloroalkene degradation;Butanoate metabolism;Microbial metabolism in diverse environments;Bisphenol degradation;Benzoate degradation;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Methane metabolism"
83694,2,0,0,0,0,26,24,27,41,121,20,0,RPS6KL1;ribosomal protein S6 kinase-like 1,GO:0005840//ribosome,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,K04373//Long-term potentiation;Progesterone-mediated oocyte maturation;Oocyte meiosis;Neurotrophin signaling pathway;mTOR signaling pathway;MAPK signaling pathway
83695,0,0,0,21,25,0,0,0,17,0,9,0,RHNO1;RAD9-HUS1-RAD1 interacting nuclear orphan 1,GO:0005634//nucleus;GO:0005694//chromosome,GO:0034644//cellular response to UV;GO:0000077//DNA damage checkpoint;GO:0071479//cellular response to ionizing radiation;GO:0070318//positive regulation of G0 to G1 transition;GO:0000725//recombinational repair,GO:0005515//protein binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption
83696,0,0,1,0,31,0,49,0,87,0,6,0,TRAPPC9;trafficking protein particle complex 9,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum,GO:0030154//cell differentiation,-,-
83697,0,0,0,0,21,0,38,32,20,0,0,0,"SLC4A9;solute carrier family 4, sodium bicarbonate cotransporter, member 9",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0045177//apical part of cell,GO:0006811//ion transport;GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport,GO:0005452//inorganic anion exchanger activity,-
83698,0,1,0,0,1,0,0,5,11,0,13,0,CALN1;calneuron 1,GO:0048471//perinuclear region of cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0032588//trans-Golgi network membrane,-,GO:0005509//calcium ion binding,K02183//Alzheimer's disease;Neurotrophin signaling pathway;Melanogenesis;Glioma;Gastric acid secretion;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Phototransduction;Insulin signaling pathway;Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system;Long-term potentiation;Tuberculosis;Pertussis;Alcoholism
83699,0,143,23,264,959,17,32,42,23,0,0,0,SH3BGRL2;SH3 domain binding glutamate-rich protein like 2,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,-,GO:0017124//SH3 domain binding,-
837,0,0,0,0,0,0,0,0,9,0,0,0,"CASP4;caspase 4, apoptosis-related cysteine peptidase",GO:0005739//mitochondrion;GO:0072557//IPAF inflammasome complex;GO:0005737//cytoplasm;GO:0072559//NLRP3 inflammasome complex;GO:0005789//endoplasmic reticulum membrane;GO:0097169//AIM2 inflammasome complex,GO:0050727//regulation of inflammatory response;GO:0097194//execution phase of apoptosis;GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process;GO:0006508//proteolysis,GO:0004197//cysteine-type endopeptidase activity,-
83700,75,245,219,393,578,17,0,198,35,0,617,0,JAM3;junctional adhesion molecule 3,GO:0005923//tight junction;GO:0030057//desmosome;GO:0044291//cell-cell contact zone;GO:0005615//extracellular space;GO:0043220//Schmidt-Lanterman incisure;GO:0005886//plasma membrane;GO:0033010//paranodal junction;GO:0016021//integral component of membrane,GO:0002250//adaptive immune response;GO:0007596//blood coagulation;GO:0001780//neutrophil homeostasis;GO:0042552//myelination;GO:0019226//transmission of nerve impulse;GO:0007160//cell-matrix adhesion;GO:0090022//regulation of neutrophil chemotaxis;GO:0002318//myeloid progenitor cell differentiation;GO:0007286//spermatid development;GO:0030198//extracellular matrix organization;GO:0030010//establishment of cell polarity;GO:0002523//leukocyte migration involved in inflammatory response;GO:0001525//angiogenesis;GO:0050900//leukocyte migration;GO:0090138//regulation of actin cytoskeleton organization by cell-cell adhesion,GO:0005515//protein binding;GO:0005178//integrin binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K06785//Cell adhesion molecules (CAMs);Tight junction;Epithelial cell signaling in Helicobacter pylori infection;Leukocyte transendothelial migration
83706,0,13,0,0,21,5,0,60,26,0,6,0,FERMT3;fermitin family member 3,GO:0002102//podosome;GO:0042995//cell projection;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction,GO:0070527//platelet aggregation;GO:0034446//substrate adhesion-dependent cell spreading;GO:0033632//regulation of cell-cell adhesion mediated by integrin;GO:0033622//integrin activation;GO:0007229//integrin-mediated signaling pathway;GO:0007159//leukocyte cell-cell adhesion,GO:0005178//integrin binding,K06271//HTLV-I infection;Focal adhesion
83714,0,39,43,77,255,0,33,0,99,58,224,0,NRIP2;nuclear receptor interacting protein 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006508//proteolysis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0004190//aspartic-type endopeptidase activity,-
83715,0,0,0,0,0,0,19,51,9,0,0,0,ESPN;espin,GO:0031941//filamentous actin;GO:0032420//stereocilium;GO:0005737//cytoplasm;GO:0032426//stereocilium bundle tip;GO:0005903//brush border,GO:0007626//locomotory behavior;GO:0007605//sensory perception of sound;GO:0051491//positive regulation of filopodium assembly;GO:0030046//parallel actin filament bundle assembly,GO:0051015//actin filament binding;GO:0017124//SH3 domain binding,-
83716,0,0,0,0,12,15,13,0,25,0,6,0,CRISPLD2;cysteine-rich secretory protein LCCL domain containing 2,GO:0070062//extracellular vesicular exosome;GO:0030133//transport vesicle;GO:0031012//extracellular matrix,GO:0030324//lung development;GO:0030198//extracellular matrix organization;GO:0060325//face morphogenesis,GO:0008201//heparin binding,K11447//Transcriptional misregulation in cancer;K06560//Tuberculosis;Phagosome;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
83719,0,0,0,0,7,30,0,0,0,0,18,0,YPEL3;yippee-like 3 (Drosophila),GO:0005730//nucleolus,-,-,-
8372,0,46,0,0,25,12,0,0,0,0,64,0,HYAL3;hyaluronoglucosaminidase 3,GO:0005764//lysosome;GO:0031410//cytoplasmic vesicle;GO:0005576//extracellular region,GO:0071347//cellular response to interleukin-1;GO:0071493//cellular response to UV-B;GO:0009615//response to virus;GO:0006954//inflammatory response;GO:0005975//carbohydrate metabolic process;GO:0051216//cartilage development;GO:0030214//hyaluronan catabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0046677//response to antibiotic,GO:0001618//virus receptor activity;GO:0004415//hyalurononglucosaminidase activity;GO:0033906//hyaluronoglucuronidase activity,"K01197//Lysosome;Arginine and proline metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glycosaminoglycan degradation"
83723,0,0,0,0,0,0,18,0,21,0,0,0,"FAM57B;family with sequence similarity 57, member B",GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0045599//negative regulation of fat cell differentiation;GO:0046513//ceramide biosynthetic process,GO:0050291//sphingosine N-acyltransferase activity,-
83729,1,0,0,14,17,6,0,0,14,0,0,381,"INHBE;inhibin, beta E",GO:0005576//extracellular region,GO:0040007//growth,GO:0005179//hormone activity;GO:0008083//growth factor activity,K04667//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
83732,45,29,0,0,1,0,23,20,42,0,0,0,RIOK1;RIO kinase 1,-,GO:0006468//protein phosphorylation,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,K07178//Ribosome biogenesis in eukaryotes
83733,0,0,33,33,53,4,0,0,8,0,42,0,"SLC25A18;solute carrier family 25 (glutamate carrier), member 18",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
83734,0,0,0,0,3,13,0,0,34,0,0,0,ATG10;autophagy related 10,GO:0005737//cytoplasm;GO:0005622//intracellular,GO:0006497//protein lipidation;GO:0032446//protein modification by small protein conjugation;GO:0031401//positive regulation of protein modification process;GO:0006914//autophagy;GO:0015031//protein transport;GO:0034263//autophagy in response to ER overload,GO:0019777//Atg12 ligase activity,K08736//Mismatch repair;Colorectal cancer;Pathways in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K14443//RNA degradation;K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways
83737,0,35,1,92,235,17,0,0,107,48,9,266,ITCH;itchy E3 ubiquitin protein ligase,GO:0016020//membrane;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0001558//regulation of cell growth;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0035519//protein K29-linked ubiquitination;GO:0050687//negative regulation of defense response to virus;GO:0045087//innate immune response;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0032480//negative regulation of type I interferon production;GO:0006915//apoptotic process;GO:0046718//viral entry into host cell;GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0046329//negative regulation of JNK cascade;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0006954//inflammatory response;GO:0090085//regulation of protein deubiquitination;GO:0051607//defense response to virus;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0007219//Notch signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity",GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0043021//ribonucleoprotein complex binding;GO:0045236//CXCR chemokine receptor binding,K05632//Ubiquitin mediated proteolysis;Endocytosis
83741,0,0,0,0,0,12,0,0,26,0,0,0,TFAP2D;transcription factor AP-2 delta (activating enhancer binding protein 2 delta),GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0061379//inferior colliculus development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0043524//negative regulation of neuron apoptotic process,GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
83743,0,0,0,0,2,0,0,0,25,0,14,0,GRWD1;glutamate-rich WD repeat containing 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,-
83744,0,0,0,5,41,12,0,0,17,0,5,0,ZNF484;zinc finger protein 484,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
83746,0,48,1,29,88,43,13,45,49,0,11,0,L3MBTL2;l(3)mbt-like 2 (Drosophila),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification",GO:0042393//histone binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding,-
83752,0,0,1,0,30,0,0,0,0,0,0,0,"LONP2;lon peptidase 2, peroxisomal",GO:0005634//nucleus;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0016020//membrane,GO:0016558//protein import into peroxisome matrix;GO:0007031//peroxisome organization;GO:0006625//protein targeting to peroxisome;GO:0014070//response to organic cyclic compound;GO:0016485//protein processing;GO:0031998//regulation of fatty acid beta-oxidation;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0004176//ATP-dependent peptidase activity;GO:0019899//enzyme binding;GO:0008233//peptidase activity;GO:0002020//protease binding;GO:0005102//receptor binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding,K01338//Cell cycle - Caulobacter
83755,0,0,0,0,0,0,0,0,24,0,0,0,KRTAP4-12;keratin associated protein 4-12,GO:0045095//keratin filament,-,GO:0005515//protein binding,-
83756,18,0,0,0,0,12,0,41,25,0,0,0,"TAS1R3;taste receptor, type 1, member 3",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050917//sensory perception of umami taste;GO:0001582//detection of chemical stimulus involved in sensory perception of sweet taste;GO:0050916//sensory perception of sweet taste,GO:0046982//protein heterodimerization activity;GO:0033041//sweet taste receptor activity;GO:0008527//taste receptor activity,K04626//Carbohydrate digestion and absorption;Taste transduction
83758,0,0,0,0,0,0,0,0,5,0,10,0,"RBP5;retinol binding protein 5, cellular",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0006810//transport,GO:0016918//retinal binding;GO:0019841//retinol binding;GO:0005501//retinoid binding;GO:0005215//transporter activity,K14622//Vitamin digestion and absorption;K06210//Nicotinate and nicotinamide metabolism;Metabolic pathways
83759,0,0,0,0,55,21,0,0,9,0,0,0,RBM4B;RNA binding motif protein 4B,GO:0005730//nucleolus,GO:0032922//circadian regulation of gene expression;GO:0006417//regulation of translation;GO:0043153//entrainment of circadian clock by photoperiod;GO:0007623//circadian rhythm;GO:0006397//mRNA processing;GO:0010628//positive regulation of gene expression;GO:0008380//RNA splicing,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
83787,0,0,69,20,68,13,0,62,53,0,22,52,ARMC10;armadillo repeat containing 10,GO:0005789//endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0040008//regulation of growth,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption
8379,0,0,0,0,9,0,83,0,63,0,7,0,MAD1L1;MAD1 mitotic arrest deficient-like 1 (yeast),GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005643//nuclear pore;GO:0072686//mitotic spindle;GO:0000776//kinetochore;GO:0000777//condensed chromosome kinetochore;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005819//spindle,GO:0007094//mitotic spindle assembly checkpoint;GO:0007093//mitotic cell cycle checkpoint;GO:0090235//regulation of metaphase plate congression;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K06638//Progesterone-mediated oocyte maturation;Cell cycle
83795,0,0,0,0,0,0,16,0,0,167,0,0,"KCNK16;potassium channel, subfamily K, member 16",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,-
838,80,0,0,0,0,0,36,0,3,0,0,0,"CASP5;caspase 5, apoptosis-related cysteine peptidase",GO:0072558//NLRP1 inflammasome complex;GO:0097169//AIM2 inflammasome complex;GO:0072559//NLRP3 inflammasome complex;GO:0005737//cytoplasm;GO:0072557//IPAF inflammasome complex,GO:0042981//regulation of apoptotic process;GO:0050727//regulation of inflammatory response;GO:0097194//execution phase of apoptosis;GO:0006915//apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0006508//proteolysis;GO:0021762//substantia nigra development,GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity,K04395//NOD-like receptor signaling pathway
8382,0,0,0,0,28,0,0,0,9,0,0,0,NME5;NME/NM23 family member 5,GO:0036126//sperm flagellum,GO:0007283//spermatogenesis;GO:0006241//CTP biosynthetic process;GO:0006183//GTP biosynthetic process;GO:0042384//cilium assembly;GO:0006165//nucleoside diphosphate phosphorylation;GO:0006228//UTP biosynthetic process;GO:0003351//epithelial cilium movement;GO:0021591//ventricular system development;GO:0007286//spermatid development;GO:0009116//nucleoside metabolic process;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,GO:0005524//ATP binding;GO:0004550//nucleoside diphosphate kinase activity,K00940//Metabolic pathways;Bacterial invasion of epithelial cells;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Nitrogen metabolism;Shigellosis;Purine metabolism
8383,0,0,0,0,0,0,0,0,0,0,15,0,"OR1A1;olfactory receptor, family 1, subfamily A, member 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
83844,0,0,0,0,0,0,0,0,10,0,18,0,USP26;ubiquitin specific peptidase 26,GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding;GO:0036459//ubiquitinyl hydrolase activity,-
83849,0,16,0,3,17,15,55,0,66,0,38,0,SYT15;synaptotagmin XV,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,"K15290//Synaptic vesicle cycle;K00253//Valine, leucine and isoleucine degradation;Metabolic pathways;Butanoate metabolism;Fatty acid metabolism;Geraniol degradation;Biosynthesis of secondary metabolites"
83850,85,0,0,0,0,28,1,58,36,2,0,413,ESYT3;extended synaptotagmin-like protein 3,GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0044232//organelle membrane contact site;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006869//lipid transport,GO:0008289//lipid binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K15290//Synaptic vesicle cycle
83851,0,43,0,0,0,7,9,0,0,0,0,0,SYT16;synaptotagmin XVI,-,GO:0006887//exocytosis,-,K15290//Synaptic vesicle cycle
83852,0,0,0,14,4,0,42,0,16,0,0,0,"SETDB2;SET domain, bifurcated 2",GO:0005634//nucleus;GO:0005694//chromosome,"GO:0001947//heart looping;GO:0051567//histone H3-K9 methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007067//mitotic nuclear division;GO:0070986//left/right axis specification;GO:0007059//chromosome segregation",GO:0046974//histone methyltransferase activity (H3-K9 specific);GO:0003677//DNA binding;GO:0008270//zinc ion binding,K11421//Lysine degradation
83853,0,0,0,3,1,0,0,0,0,0,0,0,ROPN1L;rhophilin associated tail protein 1-like,GO:0031514//motile cilium;GO:0005737//cytoplasm,GO:0048240//sperm capacitation;GO:0003351//epithelial cilium movement;GO:0001932//regulation of protein phosphorylation;GO:0030317//sperm motility,GO:0005515//protein binding,-
83854,0,74,236,151,246,0,0,0,15,0,137,0,ANGPTL6;angiopoietin-like 6,GO:0030141//secretory granule;GO:0070062//extracellular vesicular exosome,GO:0030154//cell differentiation;GO:0001525//angiogenesis,-,-
83855,0,0,31,0,15,0,22,0,46,0,0,0,KLF16;Kruppel-like factor 16,GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0007212//dopamine receptor signaling pathway",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
83856,27,0,0,0,0,72,1,0,47,0,0,0,FSD1L;fibronectin type III and SPRY domain containing 1-like,-,-,-,K08285//Ubiquitin mediated proteolysis
83857,0,0,0,0,0,0,29,145,63,0,9,0,TMTC1;transmembrane and tetratricopeptide repeat containing 1,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,-,-,K09667//Other types of O-glycan biosynthesis
83858,101,0,0,0,0,13,0,0,38,1,10,0,"ATAD3B;ATPase family, AAA domain containing 3B",GO:0005743//mitochondrial inner membrane,-,GO:0005524//ATP binding,K12196//Endocytosis;K03064//Proteasome;Epstein-Barr virus infection
8386,0,0,0,5,0,0,0,0,0,0,0,0,"OR1D5;olfactory receptor, family 1, subfamily D, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007608//sensory perception of smell;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
83860,129,0,0,0,12,0,0,29,34,40,0,0,"TAF3;TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa",GO:0005669//transcription factor TFIID complex;GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0051457//maintenance of protein location in nucleus;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0002039//p53 binding;GO:0008270//zinc ion binding,K14650//Herpes simplex infection;Basal transcription factors
83861,0,0,0,21,5,0,11,0,25,0,0,0,RSPH3;radial spoke 3 homolog (Chlamydomonas),-,-,-,-
83862,80,0,2,0,0,32,0,0,22,0,0,0,TMEM120A;transmembrane protein 120A,GO:0016021//integral component of membrane,-,-,K14574//Ribosome biogenesis in eukaryotes
8387,0,0,0,0,0,0,0,0,8,0,0,0,"OR1E1;olfactory receptor, family 1, subfamily E, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
83871,69,0,0,0,1,0,0,0,14,0,0,0,"RAB34;RAB34, member RAS oncogene family",GO:0032587//ruffle membrane;GO:0005795//Golgi stack;GO:0031985//Golgi cisterna;GO:0048471//perinuclear region of cytoplasm;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0031982//vesicle,GO:0090385//phagosome-lysosome fusion;GO:0044351//macropinocytosis;GO:0072659//protein localization to plasma membrane;GO:0019882//antigen processing and presentation;GO:0032418//lysosome localization;GO:0090382//phagosome maturation;GO:0007264//small GTPase mediated signal transduction;GO:0043001//Golgi to plasma membrane protein transport,GO:0005515//protein binding;GO:0005525//GTP binding,-
83872,89,28,0,0,0,35,23,140,283,291,13,366,HMCN1;hemicentin 1,GO:0005604//basement membrane;GO:0070062//extracellular vesicular exosome;GO:0030054//cell junction;GO:0005938//cell cortex;GO:0031012//extracellular matrix,GO:0007601//visual perception;GO:0050896//response to stimulus,GO:0005509//calcium ion binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
83873,62,0,0,0,0,0,0,1,37,0,0,391,GPR61;G protein-coupled receptor 61,GO:0043235//receptor complex;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
83874,181,0,0,0,1,0,0,0,0,0,2,0,"TBC1D10A;TBC1 domain family, member 10A",GO:0005902//microvillus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:1902017//regulation of cilium assembly;GO:0042147//retrograde transport, endosome to Golgi;GO:0032851//positive regulation of Rab GTPase activity;GO:0045862//positive regulation of proteolysis;GO:0097202//activation of cysteine-type endopeptidase activity",GO:0030165//PDZ domain binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005097//Rab GTPase activator activity;GO:0005515//protein binding,K02155//Metabolic pathways;Oxidative phosphorylation;Lysosome;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Synaptic vesicle cycle;Tuberculosis
83875,0,0,0,0,20,27,14,0,46,0,0,0,BCO2;beta-carotene oxygenase 2,GO:0005739//mitochondrion;GO:0005622//intracellular,GO:2000377//regulation of reactive oxygen species metabolic process;GO:0016116//carotenoid metabolic process;GO:0016121//carotene catabolic process;GO:0055114//oxidation-reduction process;GO:0051881//regulation of mitochondrial membrane potential;GO:0042573//retinoic acid metabolic process;GO:0042574//retinal metabolic process,"GO:0046872//metal ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen",-
83876,0,0,0,0,0,12,20,0,50,0,6,0,MRO;maestro,GO:0005730//nucleolus,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
83877,0,0,0,17,24,0,32,0,15,0,0,0,TM2D2;TM2 domain containing 2,GO:0016021//integral component of membrane,-,-,K01539//Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K03511//Fanconi anemia pathway;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
83879,0,0,31,0,0,0,0,0,43,0,0,0,CDCA7;cell division cycle associated 7,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0042127//regulation of cell proliferation;GO:0006355//regulation of transcription, DNA-templated",-,-
83881,79,0,0,0,0,0,0,57,10,0,0,0,MIXL1;Mix paired-like homeobox,GO:0000790//nuclear chromatin,"GO:0006351//transcription, DNA-templated;GO:2000382//positive regulation of mesoderm development;GO:0007492//endoderm development;GO:0035987//endodermal cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007369//gastrulation;GO:0002244//hematopoietic progenitor cell differentiation;GO:0042074//cell migration involved in gastrulation;GO:0007507//heart development;GO:0048565//digestive tract development",GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0042803//protein homodimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0001085//RNA polymerase II transcription factor binding,K09381//Transcriptional misregulation in cancer
83882,0,0,0,0,0,0,0,0,14,61,0,0,TSPAN10;tetraspanin 10,GO:0016021//integral component of membrane,GO:0072594//establishment of protein localization to organelle,GO:0019899//enzyme binding,-
83884,0,0,0,0,0,0,0,0,20,65,0,0,SLC25A2;solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2,GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0000050//urea cycle;GO:0006810//transport,-,-
83886,0,1,0,0,1,19,39,0,27,0,0,0,"PRSS27;protease, serine 27",GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity,-
83887,0,53,0,10,28,14,0,0,26,0,28,0,"TTLL2;tubulin tyrosine ligase-like family, member 2",-,GO:0006464//cellular protein modification process,GO:0016874//ligase activity,"K00273//Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism;Peroxisome;Arginine and proline metabolism;D-Arginine and D-ornithine metabolism;Metabolic pathways"
83888,0,0,0,0,0,22,0,0,0,0,0,0,FGFBP2;fibroblast growth factor binding protein 2,GO:0005615//extracellular space,-,GO:0019838//growth factor binding,-
83889,0,0,24,5,0,7,20,50,79,0,23,0,WDR87;WD repeat domain 87,-,-,-,K11423//Lysine degradation
83891,0,29,0,8,79,42,0,0,24,0,4,0,SNX25;sorting nexin 25,GO:0010008//endosome membrane,GO:0015031//protein transport;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0032801//receptor catabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0035091//phosphatidylinositol binding;GO:0034713//type I transforming growth factor beta receptor binding,-
83892,0,0,0,8,44,0,20,0,31,0,0,0,KCTD10;potassium channel tetramerization domain containing 10,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0036038//TCTN-B9D complex;GO:0005634//nucleus,GO:0051260//protein homooligomerization;GO:0016567//protein ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity,-
83893,0,0,0,0,0,0,0,0,11,56,11,0,SPATA16;spermatogenesis associated 16,GO:0005794//Golgi apparatus,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,-,-
83896,0,0,0,0,0,11,0,0,0,0,0,0,KRTAP3-1;keratin associated protein 3-1,GO:0045095//keratin filament,-,GO:0005198//structural molecule activity,-
83897,0,0,0,0,0,17,0,0,0,0,0,0,KRTAP3-2;keratin associated protein 3-2,GO:0045095//keratin filament,-,GO:0005198//structural molecule activity;GO:0005515//protein binding,-
83899,0,0,0,0,0,0,0,0,6,0,0,4,KRTAP9-2;keratin associated protein 9-2,GO:0045095//keratin filament,-,-,-
839,0,1,2,13,49,0,2,0,1,0,11,0,"CASP6;caspase 6, apoptosis-related cysteine peptidase",GO:0005829//cytosol;GO:0005654//nucleoplasm,GO:0006915//apoptotic process;GO:0030855//epithelial cell differentiation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0006508//proteolysis,GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0042802//identical protein binding,K04396//Apoptosis
8390,0,0,0,0,0,0,0,0,10,0,0,0,"OR1G1;olfactory receptor, family 1, subfamily G, member 1",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction,GO:0004984//olfactory receptor activity;GO:0004930//G-protein coupled receptor activity,K04257//Olfactory transduction
83900,0,0,0,0,0,28,0,0,0,0,0,0,KRTAP9-3;keratin associated protein 9-3,GO:0045095//keratin filament,-,-,-
83902,0,0,0,0,0,0,0,0,12,0,0,0,KRTAP17-1;keratin associated protein 17-1,GO:0005882//intermediate filament,-,-,-
83903,7,0,0,0,0,0,65,0,31,0,0,0,GSG2;germ cell associated 2 (haspin),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005694//chromosome,"GO:0071459//protein localization to chromosome, centromeric region;GO:0007064//mitotic sister chromatid cohesion;GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:2000751//histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore;GO:0090231//regulation of spindle checkpoint",GO:0072354//histone kinase activity (H3-T3 specific);GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0003677//DNA binding,-
83930,0,34,1,46,55,11,0,0,4,1,0,0,STARD3NL;STARD3 N-terminal like,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane,-,-,-
83931,0,0,0,14,24,0,0,0,48,0,1,0,STK40;serine/threonine kinase 40,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0003016//respiratory system process;GO:0060425//lung morphogenesis;GO:0048286//lung alveolus development;GO:0043066//negative regulation of apoptotic process;GO:0005977//glycogen metabolic process;GO:0006468//protein phosphorylation;GO:0043408//regulation of MAPK cascade;GO:0035264//multicellular organism growth;GO:0010468//regulation of gene expression,GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
83932,0,0,0,0,1,0,0,57,42,0,0,0,SPRTN;SprT-like N-terminal domain,GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus,GO:0009411//response to UV;GO:0006974//cellular response to DNA damage stimulus;GO:0031398//positive regulation of protein ubiquitination;GO:0019985//translesion synthesis,GO:0003677//DNA binding;GO:0070530//K63-linked polyubiquitin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043130//ubiquitin binding,-
83933,0,0,41,0,0,52,43,10,21,0,31,0,HDAC10;histone deacetylase 10,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000118//histone deacetylase complex,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006476//protein deacetylation;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070933//histone H4 deacetylation;GO:0016568//chromatin modification;GO:0007219//Notch signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0070932//histone H3 deacetylation;GO:0014003//oligodendrocyte development",GO:0005515//protein binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0042826//histone deacetylase binding;GO:0004407//histone deacetylase activity;GO:0019899//enzyme binding;GO:0033558//protein deacetylase activity,K11407//Alcoholism
83935,0,0,0,0,0,0,0,0,46,0,0,0,TMEM133;transmembrane protein 133,GO:0016021//integral component of membrane,-,-,-
83937,107,0,0,0,0,32,0,0,0,0,0,0,RASSF4;Ras association (RalGDS/AF-6) domain family member 4,-,GO:0007049//cell cycle;GO:0007165//signal transduction,GO:0005515//protein binding,-
83939,0,45,57,151,203,0,0,0,15,0,41,1,"EIF2A;eukaryotic translation initiation factor 2A, 65kDa",GO:0005615//extracellular space;GO:0072562//blood microparticle;GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0005737//cytoplasm,GO:0006417//regulation of translation;GO:0009967//positive regulation of signal transduction;GO:0042255//ribosome assembly;GO:0032933//SREBP signaling pathway;GO:0006468//protein phosphorylation;GO:0006413//translational initiation,GO:0000049//tRNA binding;GO:0043022//ribosome binding;GO:0003743//translation initiation factor activity;GO:0005515//protein binding,-
8394,0,1,0,2,85,0,41,0,21,0,17,0,"PIP5K1A;phosphatidylinositol-4-phosphate 5-kinase, type I, alpha",GO:0016607//nuclear speck;GO:0032587//ruffle membrane;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005847//mRNA cleavage and polyadenylation specificity factor complex;GO:0030027//lamellipodium;GO:0005737//cytoplasm,GO:0060326//cell chemotaxis;GO:0010761//fibroblast migration;GO:0044281//small molecule metabolic process;GO:0072661//protein targeting to plasma membrane;GO:0031532//actin cytoskeleton reorganization;GO:0008654//phospholipid biosynthetic process;GO:0007165//signal transduction;GO:0032863//activation of Rac GTPase activity;GO:0097178//ruffle assembly;GO:0016477//cell migration;GO:0006909//phagocytosis;GO:0006644//phospholipid metabolic process;GO:0048041//focal adhesion assembly;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0006650//glycerophospholipid metabolic process;GO:0030216//keratinocyte differentiation,GO:0005524//ATP binding;GO:0019900//kinase binding;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0005515//protein binding,K00889//Inositol phosphate metabolism;Focal adhesion;Fc gamma R-mediated phagocytosis;Metabolic pathways;Regulation of actin cytoskeleton;Endocytosis;Phosphatidylinositol signaling system
83940,0,0,0,9,28,0,0,0,23,0,0,0,TATDN1;TatD DNase domain containing 1,GO:0005634//nucleus;GO:0043229//intracellular organelle,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006308//DNA catabolic process","GO:0046872//metal ion binding;GO:0004536//deoxyribonuclease activity;GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters",-
83941,0,0,0,0,0,13,24,0,6,0,0,0,TM2D1;TM2 domain containing 1,GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0097190//apoptotic signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0001540//beta-amyloid binding,K03511//Fanconi anemia pathway
83942,0,0,0,0,0,0,0,0,0,0,40,0,TSSK1B;testis-specific serine kinase 1B,GO:0031514//motile cilium;GO:0001669//acrosomal vesicle,GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0007286//spermatid development,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
83943,0,1,0,20,12,0,0,0,23,0,0,0,IMMP2L;IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae),GO:0016021//integral component of membrane;GO:0042720//mitochondrial inner membrane peptidase complex,GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0006627//protein processing involved in protein targeting to mitochondrion;GO:0007283//spermatogenesis;GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0008236//serine-type peptidase activity,K09648//Protein export
8395,0,0,0,0,0,17,0,0,11,0,0,0,"PIP5K1B;phosphatidylinositol-4-phosphate 5-kinase, type I, beta",GO:0001931//uropod;GO:0012505//endomembrane system;GO:0016020//membrane;GO:0005829//cytosol,GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0006661//phosphatidylinositol biosynthetic process,GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding,K00889//Phosphatidylinositol signaling system;Regulation of actin cytoskeleton;Metabolic pathways;Endocytosis;Fc gamma R-mediated phagocytosis;Focal adhesion;Inositol phosphate metabolism
83953,0,0,0,0,0,0,0,52,66,0,0,0,"FCAMR;Fc receptor, IgA, IgM, high affinity",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0002376//immune system process,-,K13073//Intestinal immune network for IgA production
83955,0,0,0,0,0,0,0,0,11,0,0,0,NACAP1;nascent-polypeptide-associated complex alpha polypeptide pseudogene 1,-,-,-,-
83956,0,0,40,0,0,0,0,0,15,0,0,0,RACGAP1P;Rac GTPase activating protein 1 pseudogene,-,-,-,K04450//Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;Dopaminergic synapse;Cocaine addiction;HTLV-I infection;Alcoholism;Influenza A;K08878//Chronic myeloid leukemia;Pathways in cancer
83957,0,0,0,0,0,0,0,108,0,0,0,0,FRMD8P1;FERM domain containing 8 pseudogene 1,-,-,-,-
83959,0,0,0,0,0,13,25,110,10,0,0,0,"SLC4A11;solute carrier family 4, sodium borate transporter, member 11",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane,GO:0030003//cellular cation homeostasis;GO:0015992//proton transport;GO:0006814//sodium ion transport;GO:0035445//borate transmembrane transport;GO:0042044//fluid transport;GO:0035725//sodium ion transmembrane transport;GO:0015701//bicarbonate transport,GO:0046983//protein dimerization activity;GO:0046715//borate transmembrane transporter activity;GO:0015252//hydrogen ion channel activity;GO:0015293//symporter activity;GO:0005272//sodium channel activity;GO:0015106//bicarbonate transmembrane transporter activity;GO:0005452//inorganic anion exchanger activity,-
8396,25,34,0,0,51,0,51,0,46,0,13,0,"PIP4K2B;phosphatidylinositol-5-phosphate 4-kinase, type II, beta",GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0006661//phosphatidylinositol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0035556//intracellular signal transduction;GO:0006644//phospholipid metabolic process;GO:0007166//cell surface receptor signaling pathway,GO:0016309//1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0005524//ATP binding;GO:0005057//receptor signaling protein activity;GO:0016308//1-phosphatidylinositol-4-phosphate 5-kinase activity,K00920//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Endocytosis;Metabolic pathways;Regulation of actin cytoskeleton
8398,0,0,0,0,0,1,0,0,55,0,8,0,"PLA2G6;phospholipase A2, group VI (cytosolic, calcium-independent)",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0016020//membrane,"GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0016042//lipid catabolic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0044281//small molecule metabolic process;GO:0045087//innate immune response;GO:0008219//cell death;GO:0046474//glycerophospholipid biosynthetic process;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0035774//positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0001934//positive regulation of protein phosphorylation;GO:0045921//positive regulation of exocytosis;GO:0032049//cardiolipin biosynthetic process;GO:0006935//chemotaxis;GO:0060135//maternal process involved in female pregnancy;GO:0035965//cardiolipin acyl-chain remodeling;GO:1901339//regulation of store-operated calcium channel activity;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0090037//positive regulation of protein kinase C signaling;GO:0007613//memory;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0045909//positive regulation of vasodilation;GO:2000304//positive regulation of ceramide biosynthetic process;GO:0034976//response to endoplasmic reticulum stress;GO:0006644//phospholipid metabolic process;GO:0014832//urinary bladder smooth muscle contraction",GO:0005516//calmodulin binding;GO:0043008//ATP-dependent protein binding;GO:0004623//phospholipase A2 activity;GO:0047499//calcium-independent phospholipase A2 activity,K01047//Linoleic acid metabolism;MAPK signaling pathway;Glutamatergic synapse;Vascular smooth muscle contraction;Metabolic pathways;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;GnRH signaling pathway;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism;Toxoplasmosis;Arachidonic acid metabolism;Fat digestion and absorption;Fc gamma R-mediated phagocytosis;Long-term depression;Fc epsilon RI signaling pathway
83983,0,0,3,0,1,0,0,1,12,0,0,0,TSSK6;testis-specific serine kinase 6,GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0007275//multicellular organismal development;GO:0035092//sperm chromatin condensation,GO:0000287//magnesium ion binding;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
83985,0,0,0,0,0,0,7,0,0,0,0,0,SPNS1;spinster homolog 1 (Drosophila),GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005765//lysosomal membrane,GO:0006869//lipid transport;GO:0055085//transmembrane transport,GO:0005515//protein binding,-
83986,0,0,0,2,0,11,22,0,25,0,0,0,ITFG3;integrin alpha FG-GAP repeat containing 3,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0009986//cell surface,-,-,-
83987,69,0,0,0,0,7,0,29,15,0,0,0,CCDC8;coiled-coil domain containing 8,GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005886//plasma membrane,GO:0000226//microtubule cytoskeleton organization;GO:0007088//regulation of mitosis;GO:0010923//negative regulation of phosphatase activity,-,-
83988,0,1,0,4,23,0,23,0,15,93,0,0,NCALD;neurocalcin delta,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0030130//clathrin coat of trans-Golgi network vesicle,GO:0007268//synaptic transmission;GO:0003073//regulation of systemic arterial blood pressure;GO:0019722//calcium-mediated signaling;GO:0016192//vesicle-mediated transport,GO:0005509//calcium ion binding;GO:0043014//alpha-tubulin binding;GO:0003779//actin binding;GO:0015631//tubulin binding;GO:0030276//clathrin binding,K13764//Phototransduction
83989,0,0,0,22,25,0,64,0,23,0,0,0,"FAM172A;family with sequence similarity 172, member A",GO:0005576//extracellular region;GO:0005783//endoplasmic reticulum,-,-,-
8399,0,0,48,0,0,0,0,0,0,0,0,0,"PLA2G10;phospholipase A2, group X",GO:0005576//extracellular region,GO:0051977//lysophospholipid transport;GO:0006654//phosphatidic acid biosynthetic process;GO:0043030//regulation of macrophage activation;GO:0032308//positive regulation of prostaglandin secretion;GO:0019369//arachidonic acid metabolic process;GO:0042632//cholesterol homeostasis;GO:0036150//phosphatidylserine acyl-chain remodeling;GO:0036152//phosphatidylethanolamine acyl-chain remodeling;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0006644//phospholipid metabolic process;GO:0007411//axon guidance;GO:0016042//lipid catabolic process;GO:0090238//positive regulation of arachidonic acid secretion;GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0090370//negative regulation of cholesterol efflux;GO:0032270//positive regulation of cellular protein metabolic process;GO:0044281//small molecule metabolic process;GO:0010884//positive regulation of lipid storage;GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0010744//positive regulation of macrophage derived foam cell differentiation,GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity;GO:0004620//phospholipase activity,K01047//GnRH signaling pathway;alpha-Linolenic acid metabolism;Serotonergic synapse;Pancreatic secretion;Vascular smooth muscle contraction;Metabolic pathways;Glutamatergic synapse;MAPK signaling pathway;Linoleic acid metabolism;Long-term depression;Fc epsilon RI signaling pathway;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Toxoplasmosis;Arachidonic acid metabolism;Ether lipid metabolism;VEGF signaling pathway;Glycerophospholipid metabolism
83990,204,0,0,0,0,8,0,0,103,0,0,282,BRIP1;BRCA1 interacting protein C-terminal helicase 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031965//nuclear membrane,GO:0000077//DNA damage checkpoint;GO:0044281//small molecule metabolic process;GO:0032508//DNA duplex unwinding;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0006302//double-strand break repair,"GO:0004003//ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0003677//DNA binding",K15362//Fanconi anemia pathway
83992,0,0,0,0,0,64,39,7,35,0,2,0,CTTNBP2;cortactin binding protein 2,GO:0008021//synaptic vesicle;GO:0005938//cell cortex;GO:0043197//dendritic spine,GO:0007420//brain development,GO:0017124//SH3 domain binding,-
83998,0,0,0,0,1,0,0,0,36,0,0,0,"REG4;regenerating islet-derived family, member 4",GO:0005576//extracellular region;GO:0005737//cytoplasm,-,GO:0008201//heparin binding;GO:0005509//calcium ion binding;GO:2001065//mannan binding,K06560//Tuberculosis;Phagosome
83999,0,1,1,10,0,0,11,0,90,102,15,0,KREMEN1;kringle containing transmembrane protein 1,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0007154//cell communication;GO:0060828//regulation of canonical Wnt signaling pathway;GO:0016055//Wnt signaling pathway,GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K01343//Transcriptional misregulation in cancer;Complement and coagulation cascades;K11447//Transcriptional misregulation in cancer
840,0,29,2,25,128,0,0,0,7,0,0,0,"CASP7;caspase 7, apoptosis-related cysteine peptidase",GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0097194//execution phase of apoptosis;GO:0006915//apoptotic process;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0097193//intrinsic apoptotic signaling pathway;GO:0006508//proteolysis,GO:0004197//cysteine-type endopeptidase activity;GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding,K04397//Pertussis;Legionellosis;Apoptosis;Alzheimer's disease
84000,0,0,0,0,0,0,22,0,30,0,4,0,"TMPRSS13;transmembrane protease, serine 13",GO:0016021//integral component of membrane;GO:0072562//blood microparticle,GO:0006508//proteolysis;GO:0006898//receptor-mediated endocytosis,GO:0005044//scavenger receptor activity;GO:0004252//serine-type endopeptidase activity,K09643//Influenza A
84002,0,0,0,12,48,0,0,0,31,0,0,0,"B3GNT5;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0007417//central nervous system development;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0009247//glycolipid biosynthetic process;GO:0006486//protein glycosylation;GO:0009103//lipopolysaccharide biosynthetic process,"GO:0047256//lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity;GO:0008457//beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity;GO:0008917//lipopolysaccharide N-acetylglucosaminyltransferase activity;GO:0008378//galactosyltransferase activity",K03766//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
8402,1,86,0,32,75,0,0,0,0,2,14,0,"SLC25A11;solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11",GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0006094//gluconeogenesis;GO:0015742//alpha-ketoglutarate transport;GO:0006810//transport;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process,GO:0015367//oxoglutarate:malate antiporter activity;GO:0044822//poly(A) RNA binding,-
8403,0,0,0,0,0,0,25,0,13,0,0,0,SOX14;SRY (sex determining region Y)-box 14,GO:0044798//nuclear transcription factor complex,"GO:0006366//transcription from RNA polymerase II promoter;GO:2001222//regulation of neuron migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007601//visual perception;GO:0007399//nervous system development;GO:0009649//entrainment of circadian clock",GO:0043565//sequence-specific DNA binding;GO:0046982//protein heterodimerization activity;GO:0003682//chromatin binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
84033,313,43,6,32,5,127,128,143,301,299,193,19,"OBSCN;obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF",GO:0030016//myofibril;GO:0005829//cytosol;GO:0031430//M band;GO:0030018//Z disc,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007275//multicellular organismal development;GO:0006468//protein phosphorylation;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0045214//sarcomere organization;GO:0036309//protein localization to M-band,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005516//calmodulin binding;GO:0008307//structural constituent of muscle;GO:0005524//ATP binding;GO:0031432//titin binding;GO:0030506//ankyrin binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
84034,6,0,1,9,7,13,0,0,61,139,0,124,EMILIN2;elastin microfibril interfacer 2,GO:0005578//proteinaceous extracellular matrix;GO:0005581//collagen trimer;GO:0031012//extracellular matrix;GO:0005576//extracellular region,GO:0007155//cell adhesion,GO:0030023//extracellular matrix constituent conferring elasticity;GO:0005515//protein binding,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
8404,0,0,0,0,0,0,29,0,17,0,0,0,SPARCL1;SPARC-like 1 (hevin),GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0007165//signal transduction,GO:0005509//calcium ion binding,-
8405,0,58,1,53,135,0,28,0,1,0,0,0,SPOP;speckle-type POZ protein,GO:0005634//nucleus;GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0016607//nuclear speck,GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:1902237//positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:2000676//positive regulation of type B pancreatic cell apoptotic process;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0042593//glucose homeostasis,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0001085//RNA polymerase II transcription factor binding,-
84054,32,21,0,0,0,0,0,0,16,0,6,425,PCDHB19P;protocadherin beta 19 pseudogene,-,-,-,-
84056,0,0,0,12,1,10,13,0,5,0,0,0,KATNAL1;katanin p60 subunit A-like 1,GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007283//spermatogenesis;GO:0006200//ATP catabolic process;GO:0051013//microtubule severing,GO:0005524//ATP binding;GO:0008568//microtubule-severing ATPase activity;GO:0008017//microtubule binding,-
84058,50,0,0,8,15,29,19,0,4,0,0,0,WDR54;WD repeat domain 54,-,-,-,-
84059,102,0,0,1,0,64,76,1,126,5,14,3,GPR98;G protein-coupled receptor 98,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0002142//stereocilia ankle link complex;GO:0009986//cell surface;GO:0043235//receptor complex,GO:0050877//neurological system process;GO:0007605//sensory perception of sound;GO:0048496//maintenance of organ identity;GO:0007601//visual perception;GO:0007218//neuropeptide signaling pathway;GO:0045494//photoreceptor cell maintenance;GO:0060122//inner ear receptor stereocilium organization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0016337//single organismal cell-cell adhesion;GO:0050910//detection of mechanical stimulus involved in sensory perception of sound;GO:0050953//sensory perception of light stimulus;GO:0007399//nervous system development,GO:0005509//calcium ion binding;GO:0017022//myosin binding;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity,K05849//Hypertrophic cardiomyopathy (HCM);Calcium signaling pathway;Dilated cardiomyopathy;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Protein digestion and absorption;Cardiac muscle contraction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
8406,0,0,0,0,0,7,0,0,15,0,0,0,"SRPX;sushi-repeat containing protein, X-linked",GO:0005776//autophagic vacuole;GO:0009986//cell surface;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:2001241//positive regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0060244//negative regulation of cell proliferation involved in contact inhibition;GO:0007155//cell adhesion;GO:0006914//autophagy;GO:0034976//response to endoplasmic reticulum stress;GO:0001845//phagolysosome assembly,-,K06496//Cell adhesion molecules (CAMs);Malaria;Staphylococcus aureus infection;K14407//mRNA surveillance pathway;K06494//Cell adhesion molecules (CAMs);Malaria;African trypanosomiasis
84060,0,0,0,0,12,0,26,0,9,0,0,0,RBM48;RNA binding motif protein 48,GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0003723//RNA binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism
84061,142,2,0,8,29,18,25,0,0,0,0,25,MAGT1;magnesium transporter 1,GO:0016020//membrane;GO:0008250//oligosaccharyltransferase complex;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0050890//cognition;GO:0043687//post-translational protein modification;GO:0006487//protein N-linked glycosylation;GO:0015693//magnesium ion transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process,GO:0015095//magnesium ion transmembrane transporter activity,K12669//Metabolic pathways;Various types of N-glycan biosynthesis;Protein processing in endoplasmic reticulum;N-Glycan biosynthesis
84062,0,0,0,0,9,10,20,0,26,0,0,0,DTNBP1;dystrobrevin binding protein 1,GO:0043005//neuron projection;GO:0010008//endosome membrane;GO:0014069//postsynaptic density;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0030424//axon;GO:0005634//nucleus;GO:0045211//postsynaptic membrane;GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0031083//BLOC-1 complex;GO:0005829//cytosol;GO:0016528//sarcoplasm;GO:0042383//sarcolemma;GO:0005789//endoplasmic reticulum membrane;GO:0033162//melanosome membrane,GO:0008089//anterograde axon cargo transport;GO:0031175//neuron projection development;GO:0048812//neuron projection morphogenesis;GO:0001956//positive regulation of neurotransmitter secretion;GO:0060159//regulation of dopamine receptor signaling pathway;GO:0031532//actin cytoskeleton reorganization;GO:0048490//anterograde synaptic vesicle transport;GO:0061024//membrane organization;GO:0032438//melanosome organization;GO:0010628//positive regulation of gene expression;GO:0060155//platelet dense granule organization;GO:0014059//regulation of dopamine secretion;GO:0006892//post-Golgi vesicle-mediated transport;GO:0007596//blood coagulation,GO:0005515//protein binding,-
84063,0,0,0,0,0,0,66,123,33,139,19,0,KIRREL2;kin of IRRE like 2 (Drosophila),GO:0005886//plasma membrane;GO:0036057//slit diaphragm;GO:0016021//integral component of membrane,GO:0001933//negative regulation of protein phosphorylation;GO:0007155//cell adhesion;GO:0016337//single organismal cell-cell adhesion,-,K06255//ECM-receptor interaction;K14319//RNA transport;K06548//Cell adhesion molecules (CAMs);K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM);K06755//Axon guidance
84064,0,29,1,52,73,0,67,0,23,0,1,128,HDHD2;haloacid dehalogenase-like hydrolase domain containing 2,GO:0070062//extracellular vesicular exosome,-,GO:0046872//metal ion binding;GO:0019899//enzyme binding,K11725//Oxidative phosphorylation;K01101//Aminobenzoate degradation;Microbial metabolism in diverse environments
84065,0,0,2,0,7,12,45,0,9,0,0,0,TMEM222;transmembrane protein 222,GO:0016021//integral component of membrane,-,-,-
84066,0,0,0,0,0,13,2,44,8,0,0,0,TEX35;testis expressed 35,GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus,-,-,-
84067,17,1,0,0,1,0,10,0,8,0,0,7,"FAM160A2;family with sequence similarity 160, member A2",GO:0070695//FHF complex,GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0045022//early endosome to late endosome transport;GO:0007032//endosome organization;GO:0015031//protein transport,GO:0005515//protein binding,-
84068,0,0,0,0,0,13,52,0,5,0,0,0,"SLC10A7;solute carrier family 10, member 7",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006814//sodium ion transport,GO:0015293//symporter activity,-
84069,0,0,0,0,0,0,1,0,24,65,20,0,"PLEKHN1;pleckstrin homology domain containing, family N member 1",-,-,-,K13710//Regulation of actin cytoskeleton
8407,139,0,0,0,18,0,12,27,14,0,1,0,TAGLN2;transgelin 2,GO:0031982//vesicle;GO:0070062//extracellular vesicular exosome,GO:0030855//epithelial cell differentiation,GO:0005515//protein binding,-
84070,80,0,0,0,0,15,0,0,43,3,12,0,"FAM186B;family with sequence similarity 186, member B",GO:0043234//protein complex,-,-,-
84071,149,0,0,7,10,0,0,26,61,0,0,0,ARMC2;armadillo repeat containing 2,-,-,-,-
84072,0,0,0,0,0,13,0,0,43,0,0,0,HORMAD1;HORMA domain containing 1,GO:0005634//nucleus;GO:0005694//chromosome;GO:0000794//condensed nuclear chromosome,GO:0048477//oogenesis;GO:0001824//blastocyst development;GO:0060629//regulation of homologous chromosome segregation;GO:0042138//meiotic DNA double-strand break formation;GO:0007283//spermatogenesis;GO:0007130//synaptonemal complex assembly;GO:0007126//meiotic nuclear division;GO:0051177//meiotic sister chromatid cohesion;GO:0051598//meiotic recombination checkpoint,-,-
84073,5,0,0,0,0,0,37,0,30,0,1,186,MYCBPAP;MYCBP associated protein,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007268//synaptic transmission;GO:0007283//spermatogenesis,GO:0005515//protein binding,-
84074,0,0,0,0,1,0,0,0,18,0,8,0,QRICH2;glutamine rich 2,-,-,-,-
84075,0,0,0,10,0,0,0,0,0,0,0,523,FSCB;fibrous sheath CABYR binding protein,GO:0035686//sperm fibrous sheath;GO:0097228//sperm principal piece,-,GO:0005509//calcium ion binding,-
84076,0,0,0,0,0,0,0,0,12,0,0,0,TKTL2;transketolase-like 2,GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0004802//transketolase activity;GO:0046872//metal ion binding,K00615//Biosynthesis of ansamycins;Metabolic pathways;Pentose phosphate pathway;Carbon fixation in photosynthetic organisms;Biosynthesis of secondary metabolites;RNA degradation;Salmonella infection;Microbial metabolism in diverse environments
84077,120,0,0,2,0,30,23,15,21,0,7,0,C3orf20;chromosome 3 open reading frame 20,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,-,-,-
84078,6,1,0,0,10,0,0,0,36,0,0,0,KBTBD7;kelch repeat and BTB (POZ) domain containing 7,-,-,GO:0005515//protein binding,-
84079,0,38,0,0,54,17,0,0,35,153,4,0,ANKRD27;ankyrin repeat domain 27 (VPS9 domain),GO:0005769//early endosome;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0045022//early endosome to late endosome transport;GO:0043547//positive regulation of GTPase activity,GO:0005515//protein binding;GO:0005096//GTPase activator activity;GO:0005085//guanyl-nucleotide exchange factor activity,-
8408,16,0,0,6,43,0,10,0,63,0,0,0,ULK1;unc-51 like autophagy activating kinase 1,GO:0005829//cytosol;GO:0034273//ATG1/UKL1 signaling complex;GO:0005776//autophagic vacuole;GO:0070969//ULK1-ATG13-FIP200 complex;GO:0043005//neuron projection;GO:0030659//cytoplasmic vesicle membrane;GO:0034045//pre-autophagosomal structure membrane;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0051386//regulation of neurotrophin TRK receptor signaling pathway;GO:0031669//cellular response to nutrient levels;GO:0021933//radial glia guided migration of cerebellar granule cell;GO:0007265//Ras protein signal transduction;GO:0031102//neuron projection regeneration;GO:0031175//neuron projection development;GO:0010506//regulation of autophagy;GO:0010508//positive regulation of autophagy;GO:0048675//axon extension;GO:0042594//response to starvation;GO:0008104//protein localization;GO:0048671//negative regulation of collateral sprouting;GO:0016239//positive regulation of macroautophagy;GO:0000045//autophagic vacuole assembly;GO:0031623//receptor internalization;GO:0046777//protein autophosphorylation;GO:0021707//cerebellar granule cell differentiation;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0032403//protein complex binding;GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004674//protein serine/threonine kinase activity,K08269//mTOR signaling pathway;Regulation of autophagy
84080,1,0,66,2,0,1,0,1,13,0,5,0,ENKD1;enkurin domain containing 1,GO:0015630//microtubule cytoskeleton;GO:0005881//cytoplasmic microtubule,-,-,-
84081,0,0,0,0,37,0,0,0,80,0,0,0,NSRP1;nuclear speckle splicing regulatory protein 1,GO:0005634//nucleus;GO:0030529//ribonucleoprotein complex;GO:0016607//nuclear speck,"GO:0006913//nucleocytoplasmic transport;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0032502//developmental process;GO:0006397//mRNA processing",GO:0003729//mRNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
84083,0,0,0,0,0,11,16,0,65,0,2,0,"ZRANB3;zinc finger, RAN-binding domain containing 3",GO:0043596//nuclear replication fork,"GO:0036292//DNA rewinding;GO:0006281//DNA repair;GO:0006974//cellular response to DNA damage stimulus;GO:0045910//negative regulation of DNA recombination;GO:0031297//replication fork processing;GO:0000733//DNA strand renaturation;GO:0048478//replication fork protection;GO:0009411//response to UV;GO:0000737//DNA catabolic process, endonucleolytic",GO:0008270//zinc ion binding;GO:0036310//annealing helicase activity;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0070530//K63-linked polyubiquitin binding;GO:0003678//DNA helicase activity;GO:0004520//endodeoxyribonuclease activity;GO:0005524//ATP binding,-
84084,0,158,172,273,515,20,21,334,100,0,438,1,"RAB6C;RAB6C, member RAS oncogene family",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005622//intracellular,GO:0022402//cell cycle process;GO:0015031//protein transport;GO:0010824//regulation of centrosome duplication;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0042493//response to drug,GO:0005525//GTP binding;GO:0003924//GTPase activity,-
84085,0,0,0,22,0,13,0,0,25,0,10,0,FBXO30;F-box protein 30,-,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity,-
8409,0,1,0,15,25,0,0,0,18,0,27,0,"UXT;ubiquitously-expressed, prefoldin-like chaperone",GO:0016272//prefoldin complex;GO:0000930//gamma-tubulin complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005815//microtubule organizing center,"GO:0006457//protein folding;GO:0006351//transcription, DNA-templated;GO:0000226//microtubule cytoskeleton organization;GO:0051297//centrosome organization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0047497//mitochondrion transport along microtubule",GO:0003682//chromatin binding;GO:0051082//unfolded protein binding;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0051015//actin filament binding;GO:0048487//beta-tubulin binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
841,0,0,0,0,54,1,0,0,47,0,0,0,"CASP8;caspase 8, apoptosis-related cysteine peptidase",GO:0043005//neuron projection;GO:0097342//ripoptosome;GO:0045121//membrane raft;GO:0005741//mitochondrial outer membrane;GO:0030690//Noc1p-Noc2p complex;GO:0044297//cell body;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0031265//CD95 death-inducing signaling complex;GO:0005815//microtubule organizing center;GO:0031264//death-inducing signaling complex;GO:0005634//nucleus,"GO:0016032//viral process;GO:0060546//negative regulation of necroptotic process;GO:0032355//response to estradiol;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0045862//positive regulation of proteolysis;GO:0032025//response to cobalt ion;GO:0030101//natural killer cell activation;GO:0097190//apoptotic signaling pathway;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0097194//execution phase of apoptosis;GO:0034138//toll-like receptor 3 signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0007507//heart development;GO:0046677//response to antibiotic;GO:0001525//angiogenesis;GO:0097284//hepatocyte apoptotic process;GO:0030225//macrophage differentiation;GO:0009409//response to cold;GO:0042110//T cell activation;GO:0071407//cellular response to organic cyclic compound;GO:0034142//toll-like receptor 4 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070243//regulation of thymocyte apoptotic process;GO:0042113//B cell activation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0071260//cellular response to mechanical stimulus;GO:0006508//proteolysis;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0051291//protein heterooligomerization;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045651//positive regulation of macrophage differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0002224//toll-like receptor signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0060715//syncytiotrophoblast cell differentiation involved in labyrinthine layer development;GO:0097193//intrinsic apoptotic signaling pathway;GO:0045471//response to ethanol;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0001841//neural tube formation",GO:0008233//peptidase activity;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway;GO:0031625//ubiquitin protein ligase binding;GO:0008234//cysteine-type peptidase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0097110//scaffold protein binding;GO:0097153//cysteine-type endopeptidase activity involved in apoptotic process;GO:0046982//protein heterodimerization activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0035877//death effector domain binding,K04398//Toxoplasmosis;Viral myocarditis;Apoptosis;Herpes simplex infection;Alzheimer's disease;p53 signaling pathway;RIG-I-like receptor signaling pathway;Pathways in cancer;Chagas disease (American trypanosomiasis);Huntington's disease;Tuberculosis;Legionellosis;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway
84100,0,0,0,0,0,0,0,0,9,0,0,0,ARL6;ADP-ribosylation factor-like 6,GO:0005930//axoneme;GO:0030117//membrane coat;GO:0072372//primary cilium;GO:0060170//ciliary membrane;GO:0005737//cytoplasm;GO:0005879//axonemal microtubule;GO:0034464//BBSome;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0051258//protein polymerization;GO:0042384//cilium assembly;GO:0045444//fat cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0032402//melanosome transport;GO:0006612//protein targeting to membrane;GO:0016055//Wnt signaling pathway;GO:0007368//determination of left/right symmetry;GO:0007601//visual perception,GO:0005525//GTP binding;GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
84101,0,0,0,0,0,0,0,0,22,0,0,0,USP44;ubiquitin specific peptidase 44,GO:0005634//nucleus,GO:0060564//negative regulation of mitotic anaphase-promoting complex activity;GO:0090231//regulation of spindle checkpoint;GO:0007067//mitotic nuclear division;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination;GO:0090266//regulation of mitotic cell cycle spindle assembly checkpoint,GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0008270//zinc ion binding;GO:0004221//ubiquitin thiolesterase activity,-
84102,0,0,0,0,0,0,0,0,39,0,3,0,"SLC41A2;solute carrier family 41 (magnesium transporter), member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0008324//cation transmembrane transporter activity,-
84103,197,0,0,0,0,20,18,0,9,0,0,0,C4orf17;chromosome 4 open reading frame 17,-,-,-,-
84105,0,0,0,6,10,0,20,0,6,1,0,0,PCBD2;pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2,GO:0005634//nucleus;GO:0005739//mitochondrion,"GO:0051291//protein heterooligomerization;GO:0051289//protein homotetramerization;GO:0055114//oxidation-reduction process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006729//tetrahydrobiopterin biosynthetic process",GO:0005515//protein binding;GO:0004505//phenylalanine 4-monooxygenase activity;GO:0008124//4-alpha-hydroxytetrahydrobiopterin dehydratase activity,-
84106,48,0,0,0,0,32,27,0,10,1,0,0,PRAM1;PML-RARA regulated adaptor molecule 1,-,GO:0007229//integrin-mediated signaling pathway;GO:0043313//regulation of neutrophil degranulation,GO:0008289//lipid binding;GO:0005515//protein binding,K03260//RNA transport;Viral myocarditis;K05185//GABAergic synapse;Morphine addiction;Nicotine addiction;Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction
84107,0,0,0,0,0,16,47,0,35,0,0,0,ZIC4;Zic family member 4,GO:0005634//nucleus,-,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84108,0,0,0,0,0,0,27,0,7,0,0,0,PCGF6;polycomb group ring finger 6,GO:0005634//nucleus;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0008270//zinc ion binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0005515//protein binding,-
84109,0,0,0,0,0,32,0,0,0,0,0,0,QRFPR;pyroglutamylated RFamide peptide receptor,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0004983//neuropeptide Y receptor activity,-
8411,40,39,0,45,59,13,24,16,65,2,11,0,EEA1;early endosome antigen 1,GO:0019897//extrinsic component of plasma membrane;GO:0055037//recycling endosome;GO:0005969//serine-pyruvate aminotransferase complex;GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0016020//membrane,GO:0006906//vesicle fusion;GO:0045022//early endosome to late endosome transport;GO:0016189//synaptic vesicle to endosome fusion;GO:0006897//endocytosis,GO:0005516//calmodulin binding;GO:0042803//protein homodimerization activity;GO:0030742//GTP-dependent protein binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005545//1-phosphatidylinositol binding,K12478//Endocytosis;Phagosome;Tuberculosis
8412,0,0,0,0,1,18,0,0,72,16,44,0,BCAR3;breast cancer anti-estrogen resistance 3,-,GO:0002089//lens morphogenesis in camera-type eye;GO:0007165//signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0042493//response to drug;GO:0007264//small GTPase mediated signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,K08889//Adherens junction
84124,0,1,0,7,31,0,0,0,30,1,18,0,ZNF394;zinc finger protein 394,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
84125,92,0,0,12,19,8,17,0,31,0,0,0,LRRIQ1;leucine-rich repeats and IQ motif containing 1,-,-,-,K06106//Pathogenic Escherichia coli infection;Shigellosis;Tight junction;Bacterial invasion of epithelial cells
84126,0,0,1,0,25,0,40,0,18,24,0,0,ATRIP;ATR interacting protein,GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0000077//DNA damage checkpoint,GO:0005515//protein binding,K10905//Fanconi anemia pathway
84128,91,0,0,15,42,0,10,0,13,0,7,0,WDR75;WD repeat domain 75,GO:0005730//nucleolus;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding,K14552//Ribosome biogenesis in eukaryotes
84129,180,0,17,37,83,0,0,0,0,0,81,0,"ACAD11;acyl-CoA dehydrogenase family, member 11",GO:0031966//mitochondrial membrane;GO:0005634//nucleus;GO:0005777//peroxisome,GO:0033539//fatty acid beta-oxidation using acyl-CoA dehydrogenase,"GO:0070991//medium-chain-acyl-CoA dehydrogenase activity;GO:0004466//long-chain-acyl-CoA dehydrogenase activity;GO:0050660//flavin adenine dinucleotide binding;GO:0017099//very-long-chain-acyl-CoA dehydrogenase activity;GO:0016772//transferase activity, transferring phosphorus-containing groups",-
84131,56,0,0,0,7,40,52,0,55,0,0,0,CEP78;centrosomal protein 78kDa,GO:0005813//centrosome;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,-,-
84132,168,0,0,1,0,27,50,0,25,0,0,292,USP42;ubiquitin specific peptidase 42,-,GO:0016579//protein deubiquitination;GO:0007283//spermatogenesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0030154//cell differentiation,GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding,-
84133,0,1,0,0,1,9,0,41,14,0,0,0,ZNRF3;zinc and ring finger 3,GO:0005887//integral component of plasma membrane,"GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0016567//protein ubiquitination;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060070//canonical Wnt signaling pathway;GO:2000051//negative regulation of non-canonical Wnt signaling pathway;GO:0072089//stem cell proliferation;GO:0038018//Wnt receptor catabolic process;GO:0006511//ubiquitin-dependent protein catabolic process",GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0005109//frizzled binding,-
84134,0,0,0,0,0,0,0,0,38,0,7,0,TOMM40L;translocase of outer mitochondrial membrane 40 homolog (yeast)-like,GO:0005741//mitochondrial outer membrane;GO:0046930//pore complex;GO:0043234//protein complex,GO:0055085//transmembrane transport;GO:0015031//protein transport;GO:0006811//ion transport,GO:0015288//porin activity,K11518//Amyotrophic lateral sclerosis (ALS)
84135,0,1,0,0,9,21,15,0,42,0,2,0,"UTP15;UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)",GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,K14549//Ribosome biogenesis in eukaryotes
84138,0,0,0,7,1,0,0,0,44,0,24,0,"SLC7A6OS;solute carrier family 7, member 6 opposite strand",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0015031//protein transport;GO:0002244//hematopoietic progenitor cell differentiation,-,-
84140,0,1,0,0,0,0,0,0,55,0,30,0,"FAM161A;family with sequence similarity 161, member A",GO:0036064//ciliary basal body;GO:0032391//photoreceptor connecting cilium;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0042384//cilium assembly;GO:0007601//visual perception;GO:0050896//response to stimulus,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
84141,0,0,0,0,0,0,0,0,18,0,0,0,EVA1A;eva-1 homolog A (C. elegans),GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005765//lysosomal membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006914//autophagy;GO:0006915//apoptotic process,-,-
84142,95,0,55,59,71,26,46,138,54,0,12,0,"FAM175A;family with sequence similarity 175, member A",GO:0005634//nucleus;GO:0070531//BRCA1-A complex,GO:0045739//positive regulation of DNA repair;GO:0016568//chromatin modification;GO:0006302//double-strand break repair;GO:0031572//G2 DNA damage checkpoint;GO:0010212//response to ionizing radiation,GO:0005515//protein binding;GO:0031593//polyubiquitin binding,-
84144,91,0,0,0,0,0,0,0,7,0,0,0,"SYDE2;synapse defective 1, Rho GTPase, homolog 2 (C. elegans)",GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0032862//activation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005100//Rho GTPase activator activity,K08878//Chronic myeloid leukemia;Pathways in cancer
84146,0,0,0,18,117,51,40,0,70,10,2,0,ZNF644;zinc finger protein 644,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84148,0,13,0,4,10,0,0,7,8,0,0,0,KAT8;K(lysine) acetyltransferase 8,GO:0000776//kinetochore;GO:0000123//histone acetyltransferase complex;GO:0005634//nucleus;GO:0031965//nuclear membrane;GO:0072487//MSL complex;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm,"GO:0043982//histone H4-K8 acetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0043984//histone H4-K16 acetylation;GO:0030099//myeloid cell differentiation;GO:0006351//transcription, DNA-templated;GO:0043981//histone H4-K5 acetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006325//chromatin organization",GO:0035064//methylated histone binding;GO:0004402//histone acetyltransferase activity;GO:0016407//acetyltransferase activity;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0046972//histone acetyltransferase activity (H4-K16 specific),-
84152,2,0,0,0,0,0,0,0,0,0,10,0,"PPP1R1B;protein phosphatase 1, regulatory (inhibitor) subunit 1B",GO:0043025//neuronal cell body;GO:0005634//nucleus;GO:0005829//cytosol,"GO:0007621//negative regulation of female receptivity;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0006351//transcription, DNA-templated;GO:0006469//negative regulation of protein kinase activity;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0008542//visual learning;GO:0001975//response to amphetamine",GO:0031749//D2 dopamine receptor binding;GO:0031751//D4 dopamine receptor binding;GO:0004864//protein phosphatase inhibitor activity;GO:0008599//protein phosphatase type 1 regulator activity;GO:0031748//D1 dopamine receptor binding;GO:0031752//D5 dopamine receptor binding;GO:0004860//protein kinase inhibitor activity;GO:0031750//D3 dopamine receptor binding,K15494//Alcoholism;Dopaminergic synapse;Cocaine addiction;Amphetamine addiction
84153,73,576,101,317,692,0,14,194,202,1,985,0,"RNASEH2C;ribonuclease H2, subunit C",GO:0032299//ribonuclease H2 complex;GO:0005634//nucleus,GO:0006401//RNA catabolic process,-,K10745//DNA replication
84154,0,0,0,23,16,0,0,13,26,0,0,0,RPF2;ribosome production factor 2 homolog (S. cerevisiae),GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
84159,0,146,31,125,543,45,0,51,15,0,32,0,ARID5B;AT rich interactive domain 5B (MRF1-like),GO:0005634//nucleus,"GO:0008584//male gonad development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0060613//fat pad development;GO:0048705//skeletal system morphogenesis;GO:0009791//post-embryonic development;GO:0045444//fat cell differentiation;GO:0060021//palate development;GO:0030325//adrenal gland development;GO:0060612//adipose tissue development;GO:0060325//face morphogenesis;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0035264//multicellular organism growth;GO:0008585//female gonad development;GO:0001889//liver development;GO:0010761//fibroblast migration;GO:0048468//cell development;GO:0001822//kidney development;GO:0048644//muscle organ morphogenesis",GO:0044212//transcription regulatory region DNA binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0003677//DNA binding,K07874//Legionellosis
8416,0,108,147,198,532,0,70,86,65,0,439,0,ANXA9;annexin A9,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0009986//cell surface,GO:0016337//single organismal cell-cell adhesion;GO:0007268//synaptic transmission,GO:0015464//acetylcholine receptor activity;GO:0005544//calcium-dependent phospholipid binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding,-
84162,0,27,0,22,49,65,79,2,99,0,0,0,KIAA1109;KIAA1109,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005634//nucleus,GO:0001558//regulation of cell growth;GO:0030856//regulation of epithelial cell differentiation,GO:0005515//protein binding,-
84163,16,1,0,0,0,1,0,0,0,0,0,0,GTF2IRD2;GTF2I repeat domain containing 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,K03121//Basal transcription factors;Herpes simplex infection
84164,27,0,0,1,5,0,24,61,14,0,1,0,ASCC2;activating signal cointegrator 1 complex subunit 2,-,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
84166,0,0,0,9,0,13,59,60,36,0,24,0,"NLRC5;NLR family, CARD domain containing 5",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0060335//positive regulation of interferon-gamma-mediated signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0060339//negative regulation of type I interferon-mediated signaling pathway;GO:0043549//regulation of kinase activity,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0000979//RNA polymerase II core promoter sequence-specific DNA binding,K08060//Tuberculosis;Antigen processing and presentation;Influenza A;Primary immunodeficiency;Toxoplasmosis;K10165//Shigellosis;NOD-like receptor signaling pathway;Tuberculosis
84167,18,47,54,142,228,13,1,64,11,0,163,0,C19orf44;chromosome 19 open reading frame 44,-,-,-,-
84168,0,0,0,0,1,17,0,0,91,0,24,0,ANTXR1;anthrax toxin receptor 1,GO:0031258//lamellipodium membrane;GO:0070062//extracellular vesicular exosome;GO:0031527//filopodium membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane,GO:0022414//reproductive process;GO:0034446//substrate adhesion-dependent cell spreading;GO:0031532//actin cytoskeleton reorganization;GO:0007165//signal transduction,GO:0005518//collagen binding;GO:0051015//actin filament binding;GO:0004888//transmembrane signaling receptor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K06238//Protein digestion and absorption;Focal adhesion;ECM-receptor interaction;K06594//Regulation of actin cytoskeleton
8417,0,86,0,37,88,0,14,0,22,0,0,0,STX7;syntaxin 7,GO:0005765//lysosomal membrane;GO:0048471//perinuclear region of cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0031201//SNARE complex;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0006892//post-Golgi vesicle-mediated transport;GO:0016079//synaptic vesicle exocytosis;GO:0006886//intracellular protein transport,GO:0000149//SNARE binding;GO:0005484//SNAP receptor activity,K08488//SNARE interactions in vesicular transport;Phagosome
84171,0,0,0,0,0,0,0,0,12,0,0,0,LOXL4;lysyl oxidase-like 4,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005615//extracellular space;GO:0043235//receptor complex,GO:0055114//oxidation-reduction process;GO:0006898//receptor-mediated endocytosis,GO:0005507//copper ion binding;GO:0004720//protein-lysine 6-oxidase activity;GO:0005044//scavenger receptor activity;GO:0005515//protein binding,-
84172,0,32,0,14,102,6,0,35,57,0,0,0,"POLR1B;polymerase (RNA) I polypeptide B, 128kDa",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0010467//gene expression;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0032549//ribonucleoside binding,K03002//Pyrimidine metabolism;Purine metabolism;RNA polymerase;Metabolic pathways
84173,0,0,0,17,59,0,37,0,38,0,27,0,ELMOD3;ELMO/CED-12 domain containing 3,GO:0032420//stereocilium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0060091//kinocilium,GO:0006909//phagocytosis,GO:0005096//GTPase activator activity,K04139//Neuroactive ligand-receptor interaction
84174,0,0,0,0,0,7,26,0,24,0,0,0,SLA2;Src-like-adaptor 2,GO:0005737//cytoplasm;GO:0005770//late endosome;GO:0010008//endosome membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane,GO:0050776//regulation of immune response;GO:0030522//intracellular receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0050851//antigen receptor-mediated signaling pathway;GO:0042110//T cell activation;GO:0019724//B cell mediated immunity;GO:0050849//negative regulation of calcium-mediated signaling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050869//negative regulation of B cell activation,GO:0047485//protein N-terminus binding;GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K05854//Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;Long-term depression;NF-kappa B signaling pathway;Fc epsilon RI signaling pathway;Chemokine signaling pathway;B cell receptor signaling pathway;Fc gamma R-mediated phagocytosis;K08893//Fc gamma R-mediated phagocytosis;Chemokine signaling pathway
84176,39,0,0,0,0,23,8,46,33,1,0,0,"MYH16;myosin, heavy chain 16 pseudogene",-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
84179,19,245,104,112,108,0,39,230,5,1,133,0,MFSD7;major facilitator superfamily domain containing 7,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,-
8418,0,0,0,0,0,0,0,0,34,0,0,0,"CMAHP;cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene",GO:0005737//cytoplasm,GO:0046381//CMP-N-acetylneuraminate metabolic process;GO:0055114//oxidation-reduction process,"GO:0030338//CMP-N-acetylneuraminate monooxygenase activity;GO:0051537//2 iron, 2 sulfur cluster binding",K08080//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites
84181,102,23,1,48,35,55,55,0,184,0,19,0,CHD6;chromodomain helicase DNA binding protein 6,"GO:0005654//nucleoplasm;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0006351//transcription, DNA-templated;GO:0036091//positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress;GO:0016568//chromatin modification;GO:0006200//ATP catabolic process",GO:0003677//DNA binding;GO:0008026//ATP-dependent helicase activity;GO:0008094//DNA-dependent ATPase activity;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0001221//transcription cofactor binding,-
84182,0,0,0,0,0,0,0,0,42,0,0,0,"FAM188B;family with sequence similarity 188, member B",-,-,-,-
84186,0,0,0,13,8,0,30,0,33,0,0,61,"ZCCHC7;zinc finger, CCHC domain containing 7",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,K12597//RNA degradation
84187,165,0,0,17,20,0,34,0,18,0,0,0,TMEM164;transmembrane protein 164,GO:0016021//integral component of membrane,-,-,-
84188,111,0,0,27,134,0,29,38,13,189,0,0,FAR1;fatty acyl CoA reductase 1,GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0016021//integral component of membrane,GO:0044255//cellular lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0046474//glycerophospholipid biosynthetic process;GO:0010025//wax biosynthetic process;GO:0044281//small molecule metabolic process;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0008611//ether lipid biosynthetic process,GO:0050062//long-chain-fatty-acyl-CoA reductase activity;GO:0080019//fatty-acyl-CoA reductase (alcohol-forming) activity,"K13356//Peroxisome;Cutin, suberine and wax biosynthesis"
84189,1,0,0,0,0,0,0,0,16,0,0,1,"SLITRK6;SLIT and NTRK-like family, member 6",GO:0009986//cell surface;GO:0005887//integral component of plasma membrane,GO:0001964//startle response;GO:0007601//visual perception;GO:0002093//auditory receptor cell morphogenesis;GO:0002088//lens development in camera-type eye;GO:0007409//axonogenesis;GO:0008344//adult locomotory behavior;GO:0031223//auditory behavior;GO:0007605//sensory perception of sound;GO:0021562//vestibulocochlear nerve development;GO:0007416//synapse assembly;GO:0090102//cochlea development;GO:0060384//innervation;GO:0035264//multicellular organism growth,-,K06838//Axon guidance;K06850//Axon guidance
8419,1,0,0,0,0,6,0,0,17,147,0,0,"BFSP2;beaded filament structural protein 2, phakinin",GO:0005737//cytoplasm;GO:0005882//intermediate filament;GO:0005886//plasma membrane,GO:0048469//cell maturation;GO:0050896//response to stimulus;GO:0070307//lens fiber cell development;GO:0007601//visual perception;GO:0045104//intermediate filament cytoskeleton organization,GO:0005212//structural constituent of eye lens;GO:0005200//structural constituent of cytoskeleton,-
84190,0,0,18,30,0,25,22,0,38,0,0,0,METTL25;methyltransferase like 25,-,GO:0032259//methylation,GO:0008168//methyltransferase activity,K05287//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
84191,0,0,0,22,66,0,0,0,0,0,0,0,"FAM96A;family with sequence similarity 96, member A",GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0007059//chromosome segregation,GO:0046872//metal ion binding,K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
84193,0,198,5,105,196,37,0,53,10,0,3,0,SETD3;SET domain containing 3,GO:0000790//nuclear chromatin,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0018026//peptidyl-lysine monomethylation;GO:0018023//peptidyl-lysine trimethylation;GO:0051149//positive regulation of muscle cell differentiation;GO:0010452//histone H3-K36 methylation;GO:0006351//transcription, DNA-templated;GO:0018027//peptidyl-lysine dimethylation;GO:0051568//histone H3-K4 methylation",GO:0046975//histone methyltransferase activity (H3-K36 specific);GO:0003713//transcription coactivator activity;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0001102//RNA polymerase II activating transcription factor binding,K05662//ABC transporters
84196,0,53,0,0,27,0,72,0,126,0,12,0,USP48;ubiquitin specific peptidase 48,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004843//ubiquitin-specific protease activity,-
84197,0,18,0,2,1,0,0,0,16,0,0,0,POMK;protein-O-mannose kinase,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0001764//neuron migration;GO:0050905//neuromuscular process;GO:0007420//brain development;GO:0006493//protein O-linked glycosylation;GO:0046835//carbohydrate phosphorylation;GO:0006468//protein phosphorylation;GO:0019233//sensory perception of pain;GO:0007611//learning or memory,"GO:0016773//phosphotransferase activity, alcohol group as acceptor;GO:0004672//protein kinase activity;GO:0005524//ATP binding",K06264//ECM-receptor interaction
842,3,0,1,0,4,21,0,0,42,0,0,0,"CASP9;caspase 9, apoptosis-related cysteine peptidase",GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0005634//nucleus;GO:0043293//apoptosome,GO:0043525//positive regulation of neuron apoptotic process;GO:0032496//response to lipopolysaccharide;GO:0034644//cellular response to UV;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0048015//phosphatidylinositol-mediated signaling;GO:0097193//intrinsic apoptotic signaling pathway;GO:0034349//glial cell apoptotic process;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0046677//response to antibiotic;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006915//apoptotic process;GO:0071549//cellular response to dexamethasone stimulus;GO:2001020//regulation of response to DNA damage stimulus;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008635//activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c;GO:0043065//positive regulation of apoptotic process;GO:0006508//proteolysis;GO:0032025//response to cobalt ion;GO:0042981//regulation of apoptotic process;GO:0007568//aging;GO:0006974//cellular response to DNA damage stimulus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042770//signal transduction in response to DNA damage;GO:0030220//platelet formation;GO:0032355//response to estradiol,GO:0008047//enzyme activator activity;GO:0008233//peptidase activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity,K04399//VEGF signaling pathway;p53 signaling pathway;Alzheimer's disease;Toxoplasmosis;Non-small cell lung cancer;Endometrial cancer;Legionellosis;Colorectal cancer;Amyotrophic lateral sclerosis (ALS);Viral myocarditis;Apoptosis;Small cell lung cancer;Influenza A;Prostate cancer;Tuberculosis;Parkinson's disease;Huntington's disease;Pancreatic cancer;Pathways in cancer
8420,0,0,0,0,0,0,2,0,0,0,0,0,SNHG3;small nucleolar RNA host gene 3 (non-protein coding),-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
84203,0,0,0,0,0,0,28,0,1,0,0,0,TXNDC2;thioredoxin domain containing 2 (spermatozoa),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0001520//outer dense fiber;GO:0031514//motile cilium;GO:0005730//nucleolus,GO:0007275//multicellular organismal development;GO:0045454//cell redox homeostasis;GO:0007283//spermatogenesis;GO:0006457//protein folding;GO:0006662//glycerol ether metabolic process;GO:0055114//oxidation-reduction process;GO:0030154//cell differentiation,GO:0004791//thioredoxin-disulfide reductase activity;GO:0003756//protein disulfide isomerase activity;GO:0015035//protein disulfide oxidoreductase activity;GO:0045735//nutrient reservoir activity,K03671//Pyrimidine metabolism;Selenocompound metabolism
84206,0,0,0,1,0,0,0,0,15,0,0,0,MEX3B;mex-3 RNA binding family member B,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0046777//protein autophosphorylation,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0044822//poly(A) RNA binding,-
84215,0,0,0,0,0,44,0,0,75,1,0,0,ZNF541;zinc finger protein 541,GO:0005634//nucleus,"GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development",GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0003682//chromatin binding,-
84216,0,0,0,0,0,0,0,0,54,0,0,0,TMEM117;transmembrane protein 117,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,-,-
84217,0,0,0,0,0,0,19,0,0,3,1,0,"ZMYND12;zinc finger, MYND-type containing 12",GO:0005622//intracellular,-,GO:0046872//metal ion binding,-
84219,0,99,0,3,34,0,6,80,7,0,94,0,WDR24;WD repeat domain 24,-,-,-,K13341//Peroxisome;K10865//Non-homologous end-joining;Homologous recombination
84221,0,71,0,4,46,13,0,0,9,0,131,0,SPATC1L;spermatogenesis and centriole associated 1-like,-,-,-,-
84222,0,0,0,0,0,5,0,1,0,0,0,0,TMEM191A;transmembrane protein 191A (pseudogene),GO:0016021//integral component of membrane,-,-,-
84223,0,0,0,0,10,0,0,0,28,0,0,0,IQCG;IQ motif containing G,GO:0070062//extracellular vesicular exosome,-,-,K03254//RNA transport;K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
84224,1,0,0,14,22,48,0,0,9,0,0,0,"NBPF3;neuroblastoma breakpoint family, member 3",GO:0005737//cytoplasm,-,-,-
84225,0,0,0,0,1,0,44,0,7,1,0,0,"ZMYND15;zinc finger, MYND-type containing 15",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007286//spermatid development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0042826//histone deacetylase binding;GO:0046872//metal ion binding,-
84226,0,60,38,42,117,45,0,0,41,0,149,0,C2orf16;chromosome 2 open reading frame 16,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,-,-,-
84229,0,0,0,0,12,16,17,5,17,0,13,0,CCDC135;coiled-coil domain containing 135,GO:0031514//motile cilium;GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0030154//cell differentiation,-,-
84230,0,0,0,0,0,0,26,0,37,0,0,25,"LRRC8C;leucine rich repeat containing 8 family, member C",GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0045444//fat cell differentiation;GO:0006811//ion transport,GO:0005515//protein binding,K12796//NOD-like receptor signaling pathway
84231,84,1,0,9,7,25,0,0,1,0,19,177,"TRAF7;TNF receptor-associated factor 7, E3 ubiquitin protein ligase",GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0000151//ubiquitin ligase complex,"GO:0006355//regulation of transcription, DNA-templated;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated;GO:0000185//activation of MAPKKK activity;GO:0043410//positive regulation of MAPK cascade;GO:0006915//apoptotic process",GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,-
84232,1,79,257,22,35,0,0,870,60,0,69,248,MAF1;MAF1 homolog (S. cerevisiae),GO:0005829//cytosol;GO:0030424//axon;GO:0005622//intracellular;GO:0005634//nucleus;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0060077//inhibitory synapse;GO:0005737//cytoplasm,"GO:0016480//negative regulation of transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated",GO:0001030//RNA polymerase III type 1 promoter DNA binding;GO:0001032//RNA polymerase III type 3 promoter DNA binding;GO:0001031//RNA polymerase III type 2 promoter DNA binding,-
84233,0,0,0,0,2,0,0,0,10,0,0,0,TMEM126A;transmembrane protein 126A,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0021554//optic nerve development,-,-
84236,0,67,1,5,40,0,20,56,81,0,50,0,RHBDD1;rhomboid domain containing 1,GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005739//mitochondrion;GO:0044322//endoplasmic reticulum quality control compartment,GO:0045732//positive regulation of protein catabolic process;GO:0033619//membrane protein proteolysis;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0034620//cellular response to unfolded protein;GO:2000254//regulation of male germ cell proliferation;GO:0043687//post-translational protein modification;GO:0043066//negative regulation of apoptotic process;GO:0048515//spermatid differentiation;GO:0031293//membrane protein intracellular domain proteolysis;GO:0010954//positive regulation of protein processing;GO:0006915//apoptotic process;GO:0051047//positive regulation of secretion;GO:0034644//cellular response to UV,GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0004175//endopeptidase activity,-
84239,0,0,0,0,0,10,49,0,34,0,5,0,ATP13A4;ATPase type 13A4,GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process,GO:0019829//cation-transporting ATPase activity;GO:0005524//ATP binding;GO:0046872//metal ion binding,-
8424,0,0,0,0,0,0,0,0,10,0,2,0,"BBOX1;butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1",GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:0045329//carnitine biosynthetic process;GO:0044281//small molecule metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0008270//zinc ion binding;GO:0005506//iron ion binding;GO:0008336//gamma-butyrobetaine dioxygenase activity,K00471//Lysine degradation
84240,0,0,0,3,0,37,0,0,6,0,0,0,"ZCCHC9;zinc finger, CCHC domain containing 9",-,GO:0010923//negative regulation of phosphatase activity,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,-
84243,196,0,0,0,0,8,13,0,0,0,0,1,"ZDHHC18;zinc finger, DHHC-type containing 18",GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane,GO:0034613//cellular protein localization;GO:0018345//protein palmitoylation,GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
84245,1,15,0,12,0,10,0,0,13,0,0,0,MRI1;methylthioribose-1-phosphate isomerase 1,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0042995//cell projection;GO:0005737//cytoplasm,GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0044281//small molecule metabolic process;GO:0006595//polyamine metabolic process;GO:0019284//L-methionine biosynthetic process from S-adenosylmethionine;GO:0000096//sulfur amino acid metabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0046523//S-methyl-5-thioribose-1-phosphate isomerase activity;GO:0042802//identical protein binding,K08963//Metabolic pathways;Cysteine and methionine metabolism
84246,0,11,0,1,1,0,0,1,34,0,0,0,MED10;mediator complex subunit 10,GO:0016592//mediator complex;GO:0005654//nucleoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0019827//stem cell maintenance,GO:0001104//RNA polymerase II transcription cofactor activity,-
84247,0,61,1,12,34,0,50,0,9,0,0,0,"LDOC1L;leucine zipper, down-regulated in cancer 1-like",-,-,-,-
84248,0,30,0,55,118,19,1,0,26,0,17,0,FYTTD1;forty-two-three domain containing 1,GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006406//mRNA export from nucleus,GO:0003729//mRNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12795//NOD-like receptor signaling pathway;Plant-pathogen interaction;K11447//Transcriptional misregulation in cancer
84249,0,0,0,0,0,13,0,1,21,0,29,0,PSD2;pleckstrin and Sec7 domain containing 2,GO:0005802//trans-Golgi network;GO:0043025//neuronal cell body;GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0030054//cell junction,GO:0032012//regulation of ARF protein signal transduction;GO:0030182//neuron differentiation;GO:0016192//vesicle-mediated transport;GO:0043547//positive regulation of GTPase activity,GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005543//phospholipid binding,K12494//Endocytosis
8425,77,0,0,0,0,11,26,44,0,1,4,598,LTBP4;latent transforming growth factor beta binding protein 4,GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0001558//regulation of cell growth;GO:0030198//extracellular matrix organization;GO:0030252//growth hormone secretion;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006457//protein folding;GO:0030162//regulation of proteolysis;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0045595//regulation of cell differentiation,GO:0005539//glycosaminoglycan binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005515//protein binding;GO:0050431//transforming growth factor beta binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding,K08023//TGF-beta signaling pathway
84250,0,0,0,0,0,0,49,13,64,0,0,0,ANKRD32;ankyrin repeat domain 32,GO:0005813//centrosome;GO:0005634//nucleus,-,-,-
84251,1,0,0,0,0,21,30,0,177,118,0,0,SGIP1;SH3-domain GRB2-like (endophilin) interacting protein 1,GO:0005905//coated pit;GO:0005737//cytoplasm;GO:0030136//clathrin-coated vesicle;GO:0005886//plasma membrane;GO:0030122//AP-2 adaptor complex,GO:0006897//endocytosis;GO:2000253//positive regulation of feeding behavior;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:2000507//positive regulation of energy homeostasis;GO:0002021//response to dietary excess;GO:0097320//membrane tubulation,GO:0017124//SH3 domain binding;GO:0005543//phospholipid binding;GO:0005515//protein binding;GO:0008017//microtubule binding,-
84253,111,0,0,0,59,0,15,29,98,3,0,0,GARNL3;GTPase activating Rap/RanGAP domain-like 3,-,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005083//small GTPase regulator activity;GO:0005096//GTPase activator activity,K08013//Leukocyte transendothelial migration
84254,60,0,0,0,13,0,2,0,68,61,0,0,"CAMKK1;calcium/calmodulin-dependent protein kinase kinase 1, alpha",GO:0005634//nucleus;GO:0005829//cytosol,GO:0006468//protein phosphorylation;GO:0007268//synaptic transmission,GO:0005515//protein binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,K07359//Adipocytokine signaling pathway;Alcoholism
84255,0,0,0,0,0,29,18,0,16,0,0,0,"SLC37A3;solute carrier family 37, member 3",GO:0016021//integral component of membrane,GO:0008643//carbohydrate transport;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
84256,0,0,0,0,0,0,72,0,25,0,0,1,FLYWCH1;FLYWCH-type zinc finger 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,-,GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84258,0,0,0,0,0,23,0,0,6,14,0,0,SYT3;synaptotagmin III,GO:0030672//synaptic vesicle membrane;GO:0005768//endosome;GO:0030054//cell junction;GO:0016021//integral component of membrane,GO:0051592//response to calcium ion;GO:0031340//positive regulation of vesicle fusion;GO:0017156//calcium ion-dependent exocytosis,GO:0001786//phosphatidylserine binding;GO:0019905//syntaxin binding;GO:0046872//metal ion binding;GO:0005215//transporter activity;GO:0005544//calcium-dependent phospholipid binding;GO:0030276//clathrin binding,K15290//Synaptic vesicle cycle
84259,0,1,2,0,31,32,0,0,29,0,0,0,"DCUN1D5;DCN1, defective in cullin neddylation 1, domain containing 5",-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
84260,0,0,0,0,8,0,0,0,77,150,0,0,"TCHP;trichoplein, keratin filament binding",GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0045179//apical cortex;GO:0045095//keratin filament,GO:0006915//apoptotic process;GO:0030308//negative regulation of cell growth,GO:0005515//protein binding,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
84261,0,0,12,0,0,23,0,0,23,0,0,0,FBXW9;F-box and WD repeat domain containing 9,-,GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process,GO:0005515//protein binding,-
84262,0,0,0,0,0,0,1,66,20,74,0,0,"PSMG3;proteasome (prosome, macropain) assembly chaperone 3",-,-,-,-
84263,0,50,0,3,131,30,16,0,9,0,10,0,HSDL2;hydroxysteroid dehydrogenase like 2,GO:0005777//peroxisome;GO:0005739//mitochondrion;GO:0016020//membrane,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K12405//Peroxisome;Metabolic pathways;Primary bile acid biosynthesis;K08764//Metabolic pathways;Primary bile acid biosynthesis;PPAR signaling pathway;Peroxisome
84264,105,0,0,0,0,19,0,83,10,0,0,0,HAGHL;hydroxyacylglutathione hydrolase-like,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0046872//metal ion binding,K01069//Pyruvate metabolism
84265,0,1,0,0,28,10,30,0,18,0,0,0,POLR3GL;polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005666//DNA-directed RNA polymerase III complex;GO:0000790//nuclear chromatin,GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0032481//positive regulation of type I interferon production;GO:0006386//termination of RNA polymerase III transcription;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0006385//transcription elongation from RNA polymerase III promoter;GO:0010467//gene expression,GO:0001056//RNA polymerase III activity,K03024//Epstein-Barr virus infection;RNA polymerase;Purine metabolism;Pyrimidine metabolism;Metabolic pathways;Cytosolic DNA-sensing pathway
84266,0,38,0,13,0,0,0,0,6,0,0,0,"ALKBH7;alkB, alkylation repair homolog 7 (E. coli)",GO:0005759//mitochondrial matrix,GO:0055114//oxidation-reduction process;GO:0010883//regulation of lipid storage;GO:0006974//cellular response to DNA damage stimulus;GO:0006631//fatty acid metabolic process;GO:1902445//regulation of mitochondrial membrane permeability involved in programmed necrotic cell death,GO:0046872//metal ion binding;GO:0051213//dioxygenase activity,-
84267,0,0,0,1,39,0,0,0,29,0,0,0,C9orf64;chromosome 9 open reading frame 64,-,-,-,K01539//Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
84268,0,441,228,938,2079,6,0,0,0,263,676,1,RPAIN;RPA interacting protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016605//PML body;GO:0005730//nucleolus,GO:0006281//DNA repair;GO:0006261//DNA-dependent DNA replication;GO:0006310//DNA recombination;GO:0006606//protein import into nucleus;GO:0009411//response to UV,GO:0032403//protein complex binding;GO:0046872//metal ion binding,-
84269,0,27,0,15,19,0,5,0,0,0,33,0,CHCHD5;coiled-coil-helix-coiled-coil-helix domain containing 5,GO:0005758//mitochondrial intermembrane space,-,-,-
8427,0,0,0,0,0,17,0,0,13,5,0,0,ZNF282;zinc finger protein 282,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
84271,0,40,0,8,52,1,0,0,53,0,0,0,"POLDIP3;polymerase (DNA-directed), delta interacting protein 3",GO:0016607//nuclear speck;GO:0000346//transcription export complex;GO:0035145//exon-exon junction complex;GO:0005737//cytoplasm,GO:0016973//poly(A)+ mRNA export from nucleus;GO:0045727//positive regulation of translation,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12881//mRNA surveillance pathway;RNA transport;Herpes simplex infection;Spliceosome
84272,0,0,0,0,0,0,24,1,0,374,0,0,"YIPF4;Yip1 domain family, member 4",GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0016021//integral component of membrane,-,-,-
84273,0,0,0,2,32,11,70,0,41,7,1,0,NOA1;nitric oxide associated 1,GO:0031314//extrinsic component of mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0010941//regulation of cell death;GO:0043457//regulation of cellular respiration;GO:0032543//mitochondrial translation;GO:0006915//apoptotic process;GO:0006184//GTP catabolic process;GO:0042254//ribosome biogenesis,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
84274,0,24,1,0,2,10,1,0,5,169,14,0,"COQ5;coenzyme Q5 homolog, methyltransferase (S. cerevisiae)",GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0032259//methylation;GO:0006744//ubiquinone biosynthetic process,GO:0008168//methyltransferase activity,K06127//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
84275,0,0,0,0,7,0,0,0,37,0,0,0,"SLC25A33;solute carrier family 25 (pyrimidine nucleotide carrier), member 33",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,-
84276,0,0,11,6,0,0,19,0,12,0,5,0,NICN1;nicolin 1,GO:0005634//nucleus;GO:0005874//microtubule,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
84277,0,0,0,1,27,0,12,0,31,0,0,0,"DNAJC30;DnaJ (Hsp40) homolog, subfamily C, member 30",GO:0005739//mitochondrion,-,-,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
84278,0,0,0,0,0,0,1,0,8,0,0,0,HIATL2;hippocampus abundant transcript-like 2,GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0005215//transporter activity,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
84279,0,0,0,2,1,13,0,0,27,0,0,0,PRADC1;protease-associated domain containing 1,GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,-,-,K10086//Protein processing in endoplasmic reticulum
8428,0,31,46,33,171,9,0,0,18,0,5,116,STK24;serine/threonine kinase 24,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0046777//protein autophosphorylation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0007165//signal transduction;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0048679//regulation of axon regeneration;GO:0097194//execution phase of apoptosis;GO:0030336//negative regulation of cell migration;GO:0006468//protein phosphorylation;GO:0006915//apoptotic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
84281,0,0,0,0,0,35,0,0,29,0,0,0,C2orf88;chromosome 2 open reading frame 88,GO:0005886//plasma membrane,-,GO:0034237//protein kinase A regulatory subunit binding,-
84282,119,0,0,4,0,0,15,0,26,0,0,0,RNF135;ring finger protein 135,GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0045088//regulation of innate immune response;GO:0045087//innate immune response;GO:0016567//protein ubiquitination;GO:0032480//negative regulation of type I interferon production;GO:0032728//positive regulation of interferon-beta production,GO:0008270//zinc ion binding;GO:0043021//ribonucleoprotein complex binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005515//protein binding,K10652//RIG-I-like receptor signaling pathway;Influenza A;NF-kappa B signaling pathway
84283,0,467,147,274,462,0,0,181,61,0,509,0,TMEM79;transmembrane protein 79,GO:0016021//integral component of membrane;GO:0032588//trans-Golgi network membrane;GO:0005765//lysosomal membrane,GO:0031069//hair follicle morphogenesis;GO:0042335//cuticle development;GO:0045055//regulated secretory pathway;GO:0002070//epithelial cell maturation;GO:0070268//cornification;GO:0061436//establishment of skin barrier;GO:0045684//positive regulation of epidermis development,-,-
84284,0,0,44,0,20,0,0,0,9,0,1,0,"NTPCR;nucleoside-triphosphatase, cancer-related",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0016311//dephosphorylation,"GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0017111//nucleoside-triphosphatase activity",K06928//Purine metabolism;Metabolic pathways;Thiamine metabolism
84285,0,0,0,0,0,0,0,0,12,0,0,0,EIF1AD;eukaryotic translation initiation factor 1A domain containing,GO:0005730//nucleolus;GO:0045111//intermediate filament cytoskeleton;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,GO:0006413//translational initiation,GO:0003743//translation initiation factor activity,-
84286,0,0,0,0,16,0,0,68,49,0,0,0,TMEM175;transmembrane protein 175,GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,-,-,-
84287,0,0,0,0,0,0,0,53,3,0,0,0,"ZDHHC16;zinc finger, DHHC-type containing 16",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006915//apoptotic process;GO:0018345//protein palmitoylation,GO:0008270//zinc ion binding;GO:0016409//palmitoyltransferase activity;GO:0019706//protein-cysteine S-palmitoyltransferase activity,K05766//Regulation of actin cytoskeleton
84288,12,0,0,0,32,0,0,0,45,0,0,0,EFCAB2;EF-hand calcium binding domain 2,-,-,GO:0005509//calcium ion binding,K14401//mRNA surveillance pathway;K00011//Fructose and mannose metabolism;Glycerolipid metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Galactose metabolism;Pyruvate metabolism;K02183//Amphetamine addiction;Oocyte meiosis;Vascular smooth muscle contraction;Phototransduction - fly;Plant-pathogen interaction;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Phototransduction;Insulin signaling pathway;Tuberculosis;Pertussis;Alcoholism;Long-term potentiation;Alzheimer's disease;Neurotrophin signaling pathway;Gastric acid secretion;Glioma;Melanogenesis;Olfactory transduction;Calcium signaling pathway;Salivary secretion
84289,0,33,16,8,0,21,0,79,14,0,0,0,"ING5;inhibitor of growth family, member 5",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070776//MOZ/MORF histone acetyltransferase complex,"GO:0006351//transcription, DNA-templated;GO:0043065//positive regulation of apoptotic process;GO:0045926//negative regulation of growth;GO:0006325//chromatin organization;GO:0006473//protein acetylation;GO:0006260//DNA replication;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043966//histone H3 acetylation",GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding;GO:0003682//chromatin binding,-
84290,0,0,0,0,0,0,0,0,32,0,0,0,"CAPNS2;calpain, small subunit 2",GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0006508//proteolysis,GO:0005509//calcium ion binding;GO:0004198//calcium-dependent cysteine-type endopeptidase activity,K13510//Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
84292,1,3452,1318,2455,3606,0,195,1720,221,186,3084,272,WDR83;WD repeat domain 83,GO:0005737//cytoplasm;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex,"GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions",GO:0005515//protein binding,-
84293,0,42,0,46,158,0,0,1,22,0,0,0,"FAM213A;family with sequence similarity 213, member A",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:0045670//regulation of osteoclast differentiation,GO:0016209//antioxidant activity,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K15717//Metabolic pathways;Arachidonic acid metabolism;K11447//Transcriptional misregulation in cancer
84294,0,0,0,6,0,0,0,0,16,0,22,0,"UTP23;UTP23, small subunit (SSU) processome component, homolog (yeast)",GO:0005730//nucleolus;GO:0032040//small-subunit processome,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
84295,25,23,0,15,72,32,0,0,33,0,0,0,PHF6;PHD finger protein 6,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0097110//scaffold protein binding;GO:0015631//tubulin binding;GO:0042393//histone binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding;GO:0051219//phosphoprotein binding;GO:0043021//ribonucleoprotein complex binding;GO:0019899//enzyme binding;GO:0042826//histone deacetylase binding;GO:0003677//DNA binding,K09186//Transcriptional misregulation in cancer;Lysine degradation;K11421//Lysine degradation
84296,0,0,0,0,0,44,0,101,16,0,0,0,GINS4;GINS complex subunit 4 (Sld5 homolog),GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0000278//mitotic cell cycle;GO:0006271//DNA strand elongation involved in DNA replication,GO:0005515//protein binding,-
84298,0,0,0,0,0,0,0,0,3,0,0,0,"LLPH;LLP homolog, long-term synaptic facilitation (Aplysia)",-,-,GO:0044822//poly(A) RNA binding,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
84299,0,0,0,5,26,0,0,0,0,0,0,0,MIEN1;migration and invasion enhancer 1,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane,GO:0006915//apoptotic process;GO:0051491//positive regulation of filopodium assembly;GO:0045454//cell redox homeostasis;GO:0030335//positive regulation of cell migration;GO:0043066//negative regulation of apoptotic process,GO:0008430//selenium binding,-
843,0,0,0,0,15,13,0,0,14,11,12,0,"CASP10;caspase 10, apoptosis-related cysteine peptidase",GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0097342//ripoptosome;GO:0005886//plasma membrane;GO:0031265//CD95 death-inducing signaling complex,GO:0006508//proteolysis;GO:0097190//apoptotic signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process,GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0035877//death effector domain binding;GO:0097199//cysteine-type endopeptidase activity involved in apoptotic signaling pathway,K04400//RIG-I-like receptor signaling pathway;Tuberculosis;Apoptosis
84300,0,0,1,1,22,0,26,0,0,0,0,0,UQCC2;ubiquinol-cytochrome c reductase complex assembly factor 2,GO:0005759//mitochondrial matrix;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane,GO:0002082//regulation of oxidative phosphorylation;GO:0050796//regulation of insulin secretion;GO:2001014//regulation of skeletal muscle cell differentiation,-,-
84301,0,40,0,10,25,9,0,0,26,0,8,0,DDI2;DNA-damage inducible 1 homolog 2 (S. cerevisiae),-,GO:0006508//proteolysis,GO:0004190//aspartic-type endopeptidase activity,-
84302,0,0,0,0,1,0,0,0,0,0,0,0,TMEM246;transmembrane protein 246,GO:0016021//integral component of membrane,-,-,K12613//RNA degradation
84303,0,0,0,0,0,0,0,0,16,0,0,0,CHCHD6;coiled-coil-helix-coiled-coil-helix domain containing 6,GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0042407//cristae formation;GO:0006974//cellular response to DNA damage stimulus,GO:0005515//protein binding,-
84304,11,0,1,11,1,24,0,0,1,0,18,0,NUDT22;nudix (nucleoside diphosphate linked moiety X)-type motif 22,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
84305,0,1,0,3,1,0,0,0,0,0,5,0,WIBG;within bgcn homolog (Drosophila),GO:0035145//exon-exon junction complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0045727//positive regulation of translation",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0043022//ribosome binding,K14294//RNA transport;mRNA surveillance pathway
84306,44,0,0,0,0,0,0,56,0,0,0,0,PDCD2L;programmed cell death 2-like,GO:0016020//membrane;GO:0005737//cytoplasm,GO:0007049//cell cycle,-,-
84307,0,0,0,13,74,3,8,0,22,0,0,0,ZNF397;zinc finger protein 397,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
84309,93,0,1,0,9,0,0,1,0,0,0,0,NUDT16L1;nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1,GO:0005737//cytoplasm,GO:0008152//metabolic process,GO:0050072//m7G(5')pppN diphosphatase activity;GO:0044822//poly(A) RNA binding;GO:0042803//protein homodimerization activity;GO:0030515//snoRNA binding,K01529//Purine metabolism
8431,200,0,0,0,0,0,4,0,0,0,0,0,"NR0B2;nuclear receptor subfamily 0, group B, member 2",GO:0043234//protein complex;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0043401//steroid hormone mediated signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0008203//cholesterol metabolic process;GO:0031100//organ regeneration;GO:0032024//positive regulation of insulin secretion;GO:0009749//response to glucose;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity,GO:0003707//steroid hormone receptor activity;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046965//retinoid X receptor binding;GO:0003677//DNA binding;GO:0032403//protein complex binding;GO:0046966//thyroid hormone receptor binding;GO:0003714//transcription corepressor activity;GO:0019904//protein domain specific binding;GO:0042975//peroxisome proliferator activated receptor binding,K08563//Bile secretion
84310,0,89,2,0,2,0,0,0,10,0,0,0,C7orf50;chromosome 7 open reading frame 50,-,-,GO:0044822//poly(A) RNA binding,K04456//Toxoplasmosis;Osteoclast differentiation;Endometrial cancer;VEGF signaling pathway;Focal adhesion;Glioma;Jak-STAT signaling pathway;HTLV-I infection;Fc gamma R-mediated phagocytosis;mTOR signaling pathway;Apoptosis;MAPK signaling pathway;Renal cell carcinoma;Epstein-Barr virus infection;ErbB signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Dopaminergic synapse;Influenza A;Toll-like receptor signaling pathway;Melanoma;Neurotrophin signaling pathway;Hepatitis C;Adipocytokine signaling pathway;Non-small cell lung cancer;Measles;Cholinergic synapse;Acute myeloid leukemia;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Tight junction;B cell receptor signaling pathway;Chronic myeloid leukemia;T cell receptor signaling pathway;Colorectal cancer;Insulin signaling pathway;Small cell lung cancer;Progesterone-mediated oocyte maturation;Carbohydrate digestion and absorption;Prostate cancer;Tuberculosis
84311,0,46,0,19,58,0,2,0,14,0,0,0,MRPL45;mitochondrial ribosomal protein L45,GO:0005840//ribosome;GO:0005739//mitochondrion,-,GO:0044822//poly(A) RNA binding,-
84312,0,0,0,0,0,12,0,0,27,0,22,0,BRMS1L;breast cancer metastasis-suppressor 1-like,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006355//regulation of transcription, DNA-templated",-,-
84313,0,10,0,1,16,0,0,0,4,0,5,0,VPS25;vacuolar protein sorting 25 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0010008//endosome membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0061024//membrane organization;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K12189//Endocytosis
84314,0,0,0,1,0,39,0,0,0,0,0,0,TMEM107;transmembrane protein 107,GO:0016021//integral component of membrane,GO:0042733//embryonic digit morphogenesis;GO:0042384//cilium assembly;GO:0021532//neural tube patterning,-,-
84315,129,0,0,0,1,0,0,0,8,0,0,197,MON1A;MON1 secretory trafficking family member A,-,-,-,-
84316,0,0,109,0,0,0,0,0,13,0,0,0,"NAA38;N(alpha)-acetyltransferase 38, NatC auxiliary subunit",GO:0005844//polysome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0031417//NatC complex,GO:0043066//negative regulation of apoptotic process,-,K11086//Spliceosome;Systemic lupus erythematosus
84317,0,44,148,27,96,0,0,52,9,0,63,255,CCDC115;coiled-coil domain containing 115,GO:0016020//membrane;GO:0005768//endosome;GO:0005764//lysosome,-,-,-
84318,0,46,0,23,78,13,0,0,28,0,27,0,CCDC77;coiled-coil domain containing 77,GO:0005813//centrosome;GO:0016020//membrane,-,-,K06267//ECM-receptor interaction
84319,0,0,0,0,0,38,0,50,32,0,0,0,CMSS1;cms1 ribosomal small subunit homolog (yeast),-,-,GO:0044822//poly(A) RNA binding,-
84320,0,0,0,5,1,0,0,0,23,0,0,0,ACBD6;acyl-CoA binding domain containing 6,GO:0005737//cytoplasm,-,GO:0008289//lipid binding;GO:0000062//fatty-acyl-CoA binding,K08762//PPAR signaling pathway;K13239//Peroxisome;Fatty acid metabolism
84321,134,0,0,6,15,5,0,0,4,0,0,0,THOC3;THO complex 3,GO:0000445//THO complex part of transcription export complex;GO:0000346//transcription export complex;GO:0016607//nuclear speck,GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0003723//RNA binding,K12880//RNA transport;Spliceosome
84324,0,59,0,59,225,10,0,2,19,135,13,0,SARNP;SAP domain containing ribonucleoprotein,GO:0043231//intracellular membrane-bounded organelle;GO:0000346//transcription export complex;GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006406//mRNA export from nucleus;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006417//regulation of translation",GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
84326,0,0,0,1,9,0,7,0,0,0,1,0,C16orf13;chromosome 16 open reading frame 13,-,-,-,-
84327,0,0,0,1,24,0,0,1,13,0,0,0,"ZBED3;zinc finger, BED-type containing 3",GO:0005829//cytosol;GO:0016020//membrane,GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001933//negative regulation of protein phosphorylation;GO:0050821//protein stabilization;GO:0016055//Wnt signaling pathway,GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84328,0,69,0,3,35,0,0,0,0,0,0,0,LZIC;leucine zipper and CTNNBIP1 domain containing,-,GO:0010212//response to ionizing radiation,GO:0008013//beta-catenin binding,K04493//Wnt signaling pathway
84329,0,0,47,11,0,0,0,36,14,0,15,0,HVCN1;hydrogen voltage-gated channel 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane,GO:0071294//cellular response to zinc ion;GO:0007338//single fertilization;GO:0071467//cellular response to pH;GO:0009268//response to pH;GO:0010043//response to zinc ion;GO:0035036//sperm-egg recognition;GO:0034765//regulation of ion transmembrane transport;GO:0034220//ion transmembrane transport;GO:0032504//multicellular organism reproduction;GO:0015992//proton transport,GO:0030171//voltage-gated proton channel activity;GO:0022843//voltage-gated cation channel activity,-
8433,0,0,0,0,0,0,0,0,1,0,12,0,UTF1;undifferentiated embryonic cell transcription factor 1,GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0008584//male gonad development",GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0071837//HMG box domain binding,-
84330,0,0,0,0,0,0,0,0,4,0,6,0,ZNF414;zinc finger protein 414,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84331,0,0,0,7,9,22,0,44,16,0,0,0,"FAM195A;family with sequence similarity 195, member A",-,-,-,-
84332,0,0,0,0,0,7,0,50,19,0,0,0,DYDC2;DPY30 domain containing 2,-,-,-,-
84333,71,14,1,41,58,17,0,2,49,0,0,2,PCGF5;polycomb group ring finger 5,GO:0005813//centrosome;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0031519//PcG protein complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0005515//protein binding,-
84334,0,1,0,0,3,15,0,0,16,148,0,0,"APOPT1;apoptogenic 1, mitochondrial",GO:0005739//mitochondrion,GO:0097193//intrinsic apoptotic signaling pathway;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0034393//positive regulation of smooth muscle cell apoptotic process;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,-,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
84335,0,218,162,156,295,0,15,878,116,0,503,1,AKT1S1;AKT1 substrate 1 (proline-rich),GO:0031931//TORC1 complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol,GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006469//negative regulation of protein kinase activity;GO:0045792//negative regulation of cell size;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0043523//regulation of neuron apoptotic process;GO:0032007//negative regulation of TOR signaling,GO:0005515//protein binding,-
84336,76,0,0,0,0,0,0,1,9,0,8,0,TMEM101;transmembrane protein 101,GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0004871//signal transducer activity,-
84337,0,29,2,0,15,0,0,0,2,0,9,55,ELOF1;elongation factor 1 homolog (S. cerevisiae),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding,-
8434,0,0,42,0,17,30,0,0,42,0,0,0,RECK;reversion-inducing-cysteine-rich protein with kazal motifs,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0031225//anchored component of membrane,GO:0010951//negative regulation of endopeptidase activity;GO:0030198//extracellular matrix organization;GO:0007566//embryo implantation;GO:0001955//blood vessel maturation,GO:0008191//metalloendopeptidase inhibitor activity;GO:0005515//protein binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0004866//endopeptidase inhibitor activity,K06254//ECM-receptor interaction
84340,85,28,0,91,183,0,43,0,37,0,46,0,"GFM2;G elongation factor, mitochondrial 2",GO:0005739//mitochondrion,GO:0006184//GTP catabolic process;GO:0032543//mitochondrial translation;GO:0070125//mitochondrial translational elongation;GO:0032790//ribosome disassembly,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0003746//translation elongation factor activity,-
84342,0,0,0,0,0,0,0,68,15,0,31,0,COG8;component of oligomeric golgi complex 8,GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0017119//Golgi transport complex,GO:0015031//protein transport,-,-
84343,0,0,0,13,73,0,27,0,47,0,0,0,HPS3;Hermansky-Pudlak syndrome 3,GO:0031084//BLOC-2 complex,GO:0006996//organelle organization;GO:0043473//pigmentation,-,-
8435,0,0,0,0,0,0,0,8,14,0,0,0,SOAT2;sterol O-acyltransferase 2,GO:0005903//brush border;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane,GO:0034379//very-low-density lipoprotein particle assembly;GO:0034435//cholesterol esterification;GO:0010742//macrophage derived foam cell differentiation;GO:0042632//cholesterol homeostasis;GO:0008203//cholesterol metabolic process;GO:0030299//intestinal cholesterol absorption;GO:0033344//cholesterol efflux,"GO:0015485//cholesterol binding;GO:0034736//cholesterol O-acyltransferase activity;GO:0000062//fatty-acyl-CoA binding;GO:0016746//transferase activity, transferring acyl groups",K00637//Steroid biosynthesis
8436,0,0,0,0,0,0,19,42,15,0,7,0,SDPR;serum deprivation response,GO:0005737//cytoplasm;GO:0005901//caveola;GO:0005829//cytosol,-,GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0001786//phosphatidylserine binding,-
84364,0,0,0,19,7,0,1,2,0,28,48,1,ARFGAP2;ADP-ribosylation factor GTPase activating protein 2,GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity;GO:0016192//vesicle-mediated transport,GO:0008060//ARF GTPase activator activity;GO:0008270//zinc ion binding,K12493//Endocytosis
84365,0,0,0,20,33,0,0,0,18,0,0,0,NIFK;nucleolar protein interacting with the FHA domain of MKI67,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000794//condensed nuclear chromosome;GO:0005730//nucleolus,GO:0009303//rRNA transcription;GO:0006461//protein complex assembly;GO:0016072//rRNA metabolic process;GO:0010923//negative regulation of phosphatase activity,GO:0003723//RNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
84376,0,0,0,12,72,0,0,53,59,0,35,321,HOOK3;hook microtubule-tethering protein 3,GO:0030897//HOPS complex;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005801//cis-Golgi network;GO:0005794//Golgi apparatus;GO:0005874//microtubule;GO:0005815//microtubule organizing center;GO:0070695//FHF complex;GO:0000242//pericentriolar material;GO:0034451//centriolar satellite,GO:0007032//endosome organization;GO:0022027//interkinetic nuclear migration;GO:0071539//protein localization to centrosome;GO:0031122//cytoplasmic microtubule organization;GO:0097150//neuronal stem cell maintenance;GO:0051645//Golgi localization;GO:0015031//protein transport;GO:0034454//microtubule anchoring at centrosome;GO:0007040//lysosome organization;GO:0008333//endosome to lysosome transport;GO:0050768//negative regulation of neurogenesis;GO:0045022//early endosome to late endosome transport,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K11447//Transcriptional misregulation in cancer
8438,1,0,0,28,40,0,39,0,20,0,0,0,RAD54L;RAD54-like (S. cerevisiae),GO:0005634//nucleus;GO:0005730//nucleolus,GO:0051276//chromosome organization;GO:0007126//meiotic nuclear division;GO:0000724//double-strand break repair via homologous recombination;GO:0042493//response to drug;GO:0000733//DNA strand renaturation;GO:0006310//DNA recombination;GO:0006281//DNA repair;GO:0010212//response to ionizing radiation,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0036310//annealing helicase activity,K10875//Homologous recombination
8439,0,31,1,3,62,35,0,218,63,0,50,0,NSMAF;neutral sphingomyelinase (N-SMase) activation associated factor,GO:0005737//cytoplasm,GO:0043085//positive regulation of catalytic activity;GO:0035556//intracellular signal transduction;GO:0006672//ceramide metabolic process;GO:0043065//positive regulation of apoptotic process;GO:0007165//signal transduction,GO:0016230//sphingomyelin phosphodiesterase activator activity;GO:0005057//receptor signaling protein activity;GO:0005515//protein binding,-
844,0,0,0,0,0,4,0,0,28,0,0,0,"CASQ1;calsequestrin 1 (fast-twitch, skeletal muscle)",GO:0005790//smooth endoplasmic reticulum;GO:0033017//sarcoplasmic reticulum membrane;GO:0031674//I band;GO:0016529//sarcoplasmic reticulum;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0033018//sarcoplasmic reticulum lumen;GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0014804//terminal cisterna lumen;GO:0030315//T-tubule,GO:0010033//response to organic substance;GO:0014809//regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0051258//protein polymerization;GO:0007519//skeletal muscle tissue development;GO:0007029//endoplasmic reticulum organization;GO:0045214//sarcomere organization;GO:0034220//ion transmembrane transport;GO:0009408//response to heat;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0055085//transmembrane transport,GO:0005509//calcium ion binding,K09580//Protein processing in endoplasmic reticulum;K09582//Vibrio cholerae infection;Protein processing in endoplasmic reticulum
8440,0,0,0,6,13,0,0,142,26,0,0,0,NCK2;NCK adaptor protein 2,GO:0012506//vesicle membrane;GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0042110//T cell activation;GO:0008285//negative regulation of cell proliferation;GO:0007411//axon guidance;GO:0030032//lamellipodium assembly;GO:0007015//actin filament organization;GO:0006417//regulation of translation;GO:0007165//signal transduction;GO:0007176//regulation of epidermal growth factor-activated receptor activity;GO:0007172//signal complex assembly;GO:0030838//positive regulation of actin filament polymerization;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016477//cell migration,GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity;GO:0030159//receptor signaling complex scaffold activity,K07365//Pathogenic Escherichia coli infection;ErbB signaling pathway;T cell receptor signaling pathway;Axon guidance
84417,0,0,0,0,0,0,0,41,0,0,0,0,C2orf40;chromosome 2 open reading frame 40,GO:0030133//transport vesicle;GO:0005615//extracellular space,GO:0090398//cellular senescence;GO:0008054//cyclin catabolic process;GO:0070314//G1 to G0 transition,-,-
84418,0,0,0,0,17,0,0,0,1,0,0,0,CYSTM1;cysteine-rich transmembrane module containing 1,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,-
84419,0,0,0,0,10,0,0,0,0,0,0,0,C15orf48;chromosome 15 open reading frame 48,GO:0005634//nucleus;GO:0005739//mitochondrion,-,-,K03948//Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways
8443,0,31,1,39,66,2,0,0,48,0,0,0,GNPAT;glyceronephosphate O-acyltransferase,GO:0005782//peroxisomal matrix;GO:0005777//peroxisome;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005778//peroxisomal membrane,GO:0007584//response to nutrient;GO:0042594//response to starvation;GO:0021587//cerebellum morphogenesis;GO:0008611//ether lipid biosynthetic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0070542//response to fatty acid;GO:0061024//membrane organization;GO:0046474//glycerophospholipid biosynthetic process;GO:0042493//response to drug;GO:0007416//synapse assembly;GO:0030913//paranodal junction assembly;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process,GO:0016290//palmitoyl-CoA hydrolase activity;GO:0016287//glycerone-phosphate O-acyltransferase activity;GO:0005102//receptor binding,K00649//Glycerophospholipid metabolism;Peroxisome
84432,0,0,0,0,3,0,0,0,7,0,13,0,PROK1;prokineticin 1,GO:0005576//extracellular region,GO:0001525//angiogenesis;GO:0000187//activation of MAPK activity;GO:0045765//regulation of angiogenesis;GO:0051781//positive regulation of cell division;GO:0008284//positive regulation of cell proliferation,GO:0008083//growth factor activity,-
84433,81,0,1,0,1,0,18,33,8,4,25,0,"CARD11;caspase recruitment domain family, member 11",GO:0005886//plasma membrane;GO:0042101//T cell receptor complex;GO:0045121//membrane raft;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0001772//immunological synapse,GO:0030890//positive regulation of B cell proliferation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046939//nucleotide phosphorylation;GO:0045580//regulation of T cell differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045061//thymic T cell selection;GO:0031295//T cell costimulation;GO:0042102//positive regulation of T cell proliferation;GO:0045087//innate immune response;GO:0042981//regulation of apoptotic process;GO:0050852//T cell receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0001819//positive regulation of cytokine production;GO:0045577//regulation of B cell differentiation,GO:0050700//CARD domain binding;GO:0005515//protein binding;GO:0004385//guanylate kinase activity,K07367//T cell receptor signaling pathway;NF-kappa B signaling pathway;B cell receptor signaling pathway
84435,0,0,0,0,0,0,0,27,29,0,10,302,GPR123;G protein-coupled receptor 123,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
84436,80,0,0,0,14,0,0,0,21,0,0,0,ZNF528;zinc finger protein 528,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
84437,167,24,0,8,0,0,0,0,0,0,0,0,MSANTD4;Myb/SANT-like DNA-binding domain containing 4 with coiled-coils,GO:0005634//nucleus,-,-,-
84439,0,0,50,0,0,0,16,0,1,0,10,0,HHIPL1;HHIP-like 1,GO:0005576//extracellular region;GO:0016020//membrane,GO:0055114//oxidation-reduction process;GO:0006898//receptor-mediated endocytosis;GO:0005975//carbohydrate metabolic process,"GO:0016901//oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor;GO:0048038//quinone binding;GO:0005044//scavenger receptor activity",K06231//Basal cell carcinoma;Hedgehog signaling pathway;Pathways in cancer
8444,0,0,0,0,0,0,0,20,8,0,0,0,DYRK3;dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3,GO:0005634//nucleus,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation;GO:0030218//erythrocyte differentiation,GO:0000287//magnesium ion binding;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity,-
84440,232,1,0,7,1,0,1,44,26,0,0,0,RAB11FIP4;RAB11 family interacting protein 4 (class II),GO:0055038//recycling endosome membrane;GO:0005768//endosome;GO:0030496//midbody;GO:0032154//cleavage furrow;GO:0030139//endocytic vesicle;GO:0005615//extracellular space,GO:0006810//transport;GO:0000910//cytokinesis;GO:0016032//viral process,GO:0042803//protein homodimerization activity;GO:0030306//ADP-ribosylation factor binding;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0017137//Rab GTPase binding,K12485//Endocytosis
84441,0,1,0,14,44,20,0,59,44,0,11,0,MAML2;mastermind-like 2 (Drosophila),GO:0016607//nuclear speck;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0010467//gene expression,GO:0003713//transcription coactivator activity,K06061//Notch signaling pathway
84443,14,0,0,0,0,16,49,0,95,101,0,0,FRMPD3;FERM and PDZ domain containing 3,GO:0005856//cytoskeleton,-,-,K00948//Metabolic pathways;Thiamine metabolism;Pentose phosphate pathway;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Purine metabolism;K05725//Regulation of actin cytoskeleton;ErbB signaling pathway;VEGF signaling pathway;Focal adhesion;Amoebiasis;Axon guidance;Chemokine signaling pathway;Pathways in cancer;Bacterial invasion of epithelial cells;Transcriptional misregulation in cancer;Leukocyte transendothelial migration;Small cell lung cancer
84444,104,0,0,0,5,18,12,74,39,0,31,273,DOT1L;DOT1-like histone H3K79 methyltransferase,GO:0005634//nucleus,GO:0046425//regulation of JAK-STAT cascade;GO:2000677//regulation of transcription regulatory region DNA binding;GO:0034968//histone lysine methylation,GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0018024//histone-lysine N-methyltransferase activity,K11427//Lysine degradation;Transcriptional misregulation in cancer
84445,0,0,0,0,2,0,0,0,37,0,37,0,"LZTS2;leucine zipper, putative tumor suppressor 2",GO:0030496//midbody;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0001822//kidney development;GO:0016055//Wnt signaling pathway;GO:0007067//mitotic nuclear division;GO:0051013//microtubule severing;GO:0000910//cytokinesis;GO:1900181//negative regulation of protein localization to nucleus;GO:0008285//negative regulation of cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0051168//nuclear export,GO:0005515//protein binding,-
84446,0,0,0,0,0,0,0,0,0,133,0,0,BRSK1;BR serine/threonine kinase 1,GO:0008021//synaptic vesicle;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0030054//cell junction;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007269//neurotransmitter secretion;GO:0006468//protein phosphorylation;GO:0009411//response to UV;GO:0030182//neuron differentiation;GO:0031572//G2 DNA damage checkpoint;GO:0007409//axonogenesis;GO:0010212//response to ionizing radiation;GO:0030010//establishment of cell polarity;GO:0051298//centrosome duplication;GO:0006974//cellular response to DNA damage stimulus,GO:0043015//gamma-tubulin binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0050321//tau-protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0019901//protein kinase binding,-
84447,0,1,0,0,0,0,0,11,21,1,7,313,"SYVN1;synovial apoptosis inhibitor 1, synoviolin",GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005730//nucleolus,GO:0016567//protein ubiquitination;GO:1902236//negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway;GO:0044267//cellular protein metabolic process;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0018279//protein N-linked glycosylation via asparagine;GO:0001701//in utero embryonic development,GO:0016881//acid-amino acid ligase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,K10601//Protein processing in endoplasmic reticulum;Ubiquitin mediated proteolysis
84448,0,0,0,0,0,2,33,24,37,0,8,0,"ABLIM2;actin binding LIM protein family, member 2",GO:0015629//actin cytoskeleton;GO:0030016//myofibril,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030036//actin cytoskeleton organization;GO:0007411//axon guidance",GO:0008270//zinc ion binding;GO:0003779//actin binding,K07520//Axon guidance
84449,0,0,0,0,0,0,0,0,20,0,10,0,ZNF333;zinc finger protein 333,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
8445,0,0,0,23,10,15,1,0,43,0,0,0,DYRK2;dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2,GO:0000151//ubiquitin ligase complex;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007224//smoothened signaling pathway;GO:0051534//negative regulation of NFAT protein import into nucleus;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0006974//cellular response to DNA damage stimulus;GO:0045725//positive regulation of glycogen biosynthetic process,GO:0030145//manganese ion binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0000287//magnesium ion binding;GO:0043130//ubiquitin binding;GO:0004713//protein tyrosine kinase activity,-
84450,0,0,1,6,86,40,30,0,16,0,2,520,ZNF512;zinc finger protein 512,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84451,0,0,11,16,14,0,23,69,9,0,0,1,KIAA1804;mixed lineage kinase 4,-,GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0046777//protein autophosphorylation;GO:0007257//activation of JUN kinase activity;GO:0000186//activation of MAPKK activity,GO:0042803//protein homodimerization activity;GO:0004709//MAP kinase kinase kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding,-
84455,0,0,36,0,0,0,0,0,13,0,11,0,EFCAB7;EF-hand calcium binding domain 7,-,-,GO:0005509//calcium ion binding,K02183//Alzheimer's disease;Neurotrophin signaling pathway;Melanogenesis;Glioma;Gastric acid secretion;Salivary secretion;Olfactory transduction;Calcium signaling pathway;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction;Plant-pathogen interaction;Phototransduction - fly;Phototransduction;Insulin signaling pathway;Dopaminergic synapse;GnRH signaling pathway;Phosphatidylinositol signaling system;Long-term potentiation;Tuberculosis;Pertussis;Alcoholism
84456,0,0,0,1,22,4,75,1,53,0,0,0,L3MBTL3;l(3)mbt-like 3 (Drosophila),GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0030225//macrophage differentiation;GO:0043249//erythrocyte maturation;GO:0016568//chromatin modification;GO:0030851//granulocyte differentiation;GO:0006355//regulation of transcription, DNA-templated",-,-
84457,62,101,179,250,297,0,0,81,12,1,199,0,PHYHIPL;phytanoyl-CoA 2-hydroxylase interacting protein-like,GO:0005739//mitochondrion;GO:0005737//cytoplasm,-,-,-
84458,18,54,0,42,152,0,19,0,44,0,0,0,LCOR;ligand dependent nuclear receptor corepressor,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0008134//transcription factor binding,-
8446,0,20,0,4,31,14,0,0,18,0,0,0,DUSP11;dual specificity phosphatase 11 (RNA/RNP complex 1-interacting),GO:0005634//nucleus;GO:0016607//nuclear speck,GO:0006396//RNA processing;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0016070//RNA metabolic process;GO:0098507//polynucleotide 5' dephosphorylation,"GO:0003723//RNA binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0098519//nucleotide phosphatase activity, acting on free nucleotides;GO:0016791//phosphatase activity;GO:0004651//polynucleotide 5'-phosphatase activity;GO:0044822//poly(A) RNA binding;GO:0004725//protein tyrosine phosphatase activity",-
84460,0,0,0,0,0,20,18,94,16,0,0,0,"ZMAT1;zinc finger, matrin-type 1",GO:0005634//nucleus,-,GO:0003677//DNA binding;GO:0008270//zinc ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K10137//p53 signaling pathway
84461,0,26,46,10,1,5,0,0,22,0,11,0,NEURL4;neuralized E3 ubiquitin protein ligase 4,GO:0005814//centriole,-,GO:0005515//protein binding,-
84464,0,0,0,12,0,37,0,171,80,0,0,0,SLX4;SLX4 structure-specific endonuclease subunit,"GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0048476//Holliday junction resolvase complex;GO:0033557//Slx1-Slx4 complex;GO:0070522//ERCC4-ERCC1 complex;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0000784//nuclear chromosome, telomeric region;GO:0030054//cell junction","GO:0000724//double-strand break repair via homologous recombination;GO:0006260//DNA replication;GO:0006281//DNA repair;GO:0010792//DNA double-strand break processing involved in repair via single-strand annealing;GO:0043085//positive regulation of catalytic activity;GO:0006289//nucleotide-excision repair;GO:0000737//DNA catabolic process, endonucleolytic",GO:0008047//enzyme activator activity;GO:0017108//5'-flap endonuclease activity;GO:0005515//protein binding;GO:0048257//3'-flap endonuclease activity;GO:0008821//crossover junction endodeoxyribonuclease activity,K10484//Fanconi anemia pathway
84465,44,0,0,0,0,32,0,0,45,0,23,0,MEGF11;multiple EGF-like-domains 11,GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:0034109//homotypic cell-cell adhesion;GO:0010842//retina layer formation,-,K02599//Notch signaling pathway;Dorso-ventral axis formation;Prion diseases
84466,0,0,0,4,11,40,9,58,98,0,0,0,MEGF10;multiple EGF-like-domains 10,GO:0016323//basolateral plasma membrane;GO:0001891//phagocytic cup;GO:0016021//integral component of membrane;GO:0042995//cell projection,GO:0014816//skeletal muscle satellite cell differentiation;GO:0048641//regulation of skeletal muscle tissue development;GO:0014841//skeletal muscle satellite cell proliferation;GO:0043654//recognition of apoptotic cell;GO:0014719//skeletal muscle satellite cell activation;GO:0051147//regulation of muscle cell differentiation;GO:0055001//muscle cell development;GO:0034109//homotypic cell-cell adhesion,-,K02599//Notch signaling pathway;Dorso-ventral axis formation;Prion diseases
84467,0,0,0,0,0,81,115,10,61,61,12,0,FBN3;fibrillin 3,GO:0005578//proteinaceous extracellular matrix,-,GO:0005201//extracellular matrix structural constituent;GO:0005509//calcium ion binding,-
8447,0,0,0,0,0,0,29,0,0,0,12,0,"DOC2B;double C2-like domains, beta",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0031201//SNARE complex;GO:0008021//synaptic vesicle,GO:0048791//calcium ion-dependent exocytosis of neurotransmitter;GO:0008104//protein localization;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0032024//positive regulation of insulin secretion;GO:0031340//positive regulation of vesicle fusion,GO:0005215//transporter activity;GO:0005544//calcium-dependent phospholipid binding,K15290//Synaptic vesicle cycle
8448,0,0,0,67,38,0,0,0,37,0,48,0,"DOC2A;double C2-like domains, alpha",GO:0005764//lysosome;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0043005//neuron projection,GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0007268//synaptic transmission;GO:0016079//synaptic vesicle exocytosis;GO:0007399//nervous system development,GO:0005515//protein binding;GO:0005544//calcium-dependent phospholipid binding;GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
84498,0,42,0,66,113,33,20,0,18,0,0,0,FAM120B;family with sequence similarity 120B,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0030154//cell differentiation;GO:0006355//regulation of transcription, DNA-templated",-,-
845,0,0,0,0,0,0,0,0,44,0,0,0,CASQ2;calsequestrin 2 (cardiac muscle),GO:0030018//Z disc;GO:0033018//sarcoplasmic reticulum lumen;GO:0005737//cytoplasm;GO:0005622//intracellular;GO:0016529//sarcoplasmic reticulum;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0033017//sarcoplasmic reticulum membrane;GO:0005891//voltage-gated calcium channel complex;GO:0034704//calcium channel complex,GO:0051208//sequestering of calcium ion;GO:0034220//ion transmembrane transport;GO:0086029//Purkinje myocyte to ventricular cardiac muscle cell signaling;GO:0002027//regulation of heart rate;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0006941//striated muscle contraction;GO:0005513//detection of calcium ion;GO:0071313//cellular response to caffeine;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0043267//negative regulation of potassium ion transport;GO:0051258//protein polymerization;GO:0060306//regulation of membrane repolarization;GO:0010649//regulation of cell communication by electrical coupling;GO:0055085//transmembrane transport;GO:0060048//cardiac muscle contraction;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K09582//Protein processing in endoplasmic reticulum;Vibrio cholerae infection;K09580//Protein processing in endoplasmic reticulum
8450,0,45,2,61,178,33,1,11,76,0,12,0,CUL4B;cullin 4B,GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045732//positive regulation of protein catabolic process;GO:0007049//cell cycle;GO:0035518//histone H2A monoubiquitination;GO:0070914//UV-damage excision repair;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0003684//damaged DNA binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K10609//Ubiquitin mediated proteolysis;Nucleotide excision repair
84501,0,0,0,0,0,2,21,6,36,0,0,268,SPIRE2;spire-type actin nucleation factor 2,GO:0005938//cell cortex;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0032154//cleavage furrow;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol,GO:0016192//vesicle-mediated transport;GO:0070649//formin-nucleated actin cable assembly;GO:0046907//intracellular transport;GO:0030036//actin cytoskeleton organization;GO:0051295//establishment of meiotic spindle localization;GO:0040038//polar body extrusion after meiotic divisions;GO:0015031//protein transport;GO:0036089//cleavage furrow formation,GO:0003779//actin binding,K02098//Dorso-ventral axis formation
84502,0,0,0,0,7,8,0,0,0,0,6,16,JPH4;junctophilin 4,GO:0005790//smooth endoplasmic reticulum;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0043198//dendritic shaft;GO:0016021//integral component of membrane,GO:0048167//regulation of synaptic plasticity;GO:0060314//regulation of ryanodine-sensitive calcium-release channel activity;GO:0007612//learning;GO:0060402//calcium ion transport into cytosol;GO:0050885//neuromuscular process controlling balance,-,K04575//Amyotrophic lateral sclerosis (ALS)
84503,0,0,0,8,20,21,0,0,14,0,5,0,ZNF527;zinc finger protein 527,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84504,0,0,0,0,0,0,0,0,6,0,0,0,NKX6-2;NK6 homeobox 2,GO:0005634//nucleus,"GO:0031018//endocrine pancreas development;GO:0010454//negative regulation of cell fate commitment;GO:0010455//positive regulation of cell fate commitment;GO:0021913//regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification;GO:0006355//regulation of transcription, DNA-templated;GO:0022010//central nervous system myelination;GO:0045687//positive regulation of glial cell differentiation;GO:0045686//negative regulation of glial cell differentiation;GO:0021912//regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification;GO:0050885//neuromuscular process controlling balance;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
8451,97,0,0,24,86,10,59,31,62,0,5,0,CUL4A;cullin 4A,GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0080008//Cul4-RING E3 ubiquitin ligase complex,GO:2000819//regulation of nucleotide-excision repair;GO:0097193//intrinsic apoptotic signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0016567//protein ubiquitination;GO:0030853//negative regulation of granulocyte differentiation;GO:0008284//positive regulation of cell proliferation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030097//hemopoiesis;GO:2000001//regulation of DNA damage checkpoint;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle;GO:0051246//regulation of protein metabolic process;GO:0006281//DNA repair;GO:0035019//somatic stem cell maintenance;GO:0007050//cell cycle arrest,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K10609//Nucleotide excision repair;Ubiquitin mediated proteolysis
84513,0,38,0,29,56,0,0,0,34,0,158,0,PPAPDC1B;phosphatidic acid phosphatase type 2 domain containing 1B,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0046839//phospholipid dephosphorylation,GO:0008195//phosphatidate phosphatase activity,K01080//Fat digestion and absorption;Metabolic pathways;Glycerolipid metabolism;Sphingolipid metabolism;Ether lipid metabolism;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
84514,0,1,0,0,0,0,17,0,12,0,0,0,GHDC;GH3 domain containing,GO:0005635//nuclear envelope;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,-,-,K03539//Ribosome biogenesis in eukaryotes;RNA transport
84515,0,47,14,14,42,0,0,0,0,0,8,84,MCM8;minichromosome maintenance complex component 8,GO:0005634//nucleus;GO:0097362//MCM8-MCM9 complex;GO:0005654//nucleoplasm,GO:0000724//double-strand break repair via homologous recombination;GO:0048232//male gamete generation;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0006271//DNA strand elongation involved in DNA replication;GO:0006974//cellular response to DNA damage stimulus;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007292//female gamete generation,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding,-
84516,0,26,0,13,176,52,0,0,15,3,16,0,DCTN5;dynactin 5 (p25),GO:0005813//centrosome;GO:0000777//condensed chromosome kinetochore;GO:0005829//cytosol,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,-,K10427//Vasopressin-regulated water reabsorption
84517,68,38,0,9,0,16,13,1,16,0,9,0,ACTRT3;actin-related protein T3,GO:0005737//cytoplasm;GO:0001673//male germ cell nucleus;GO:0005856//cytoskeleton,-,-,K05692//Leukocyte transendothelial migration;Shigellosis;Dilated cardiomyopathy;Bacterial invasion of epithelial cells;Tight junction;Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Influenza A;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Adherens junction;Phototransduction - fly;Viral myocarditis
84518,0,0,0,0,0,0,0,0,17,0,0,0,CNFN;cornifelin,GO:0005737//cytoplasm;GO:0001533//cornified envelope;GO:0070062//extracellular vesicular exosome,GO:0031424//keratinization,-,-
84519,129,0,0,0,0,21,19,0,38,0,12,0,ACRBP;acrosin binding protein,GO:0005634//nucleus;GO:0005576//extracellular region;GO:0001669//acrosomal vesicle,-,-,-
8452,0,33,1,55,200,9,43,0,30,0,16,0,CUL3;cullin 3,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005827//polar microtubule;GO:0005634//nucleus,GO:0007080//mitotic metaphase plate congression;GO:0043149//stress fiber assembly;GO:0017145//stem cell division;GO:0016477//cell migration;GO:0007369//gastrulation;GO:0032467//positive regulation of cytokinesis;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007229//integrin-mediated signaling pathway;GO:0048208//COPII vesicle coating;GO:0007050//cell cycle arrest;GO:0016055//Wnt signaling pathway;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0000209//protein polyubiquitination;GO:0035024//negative regulation of Rho protein signal transduction;GO:0097193//intrinsic apoptotic signaling pathway;GO:0040016//embryonic cleavage;GO:0016567//protein ubiquitination;GO:0006513//protein monoubiquitination;GO:0001831//trophectodermal cellular morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0008054//cyclin catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0030332//cyclin binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0031625//ubiquitin protein ligase binding;GO:0031208//POZ domain binding,K03869//Ubiquitin mediated proteolysis
84520,0,0,0,5,24,0,0,0,0,0,0,0,C14orf142;chromosome 14 open reading frame 142,-,-,-,-
84524,0,0,0,0,0,0,0,0,0,0,4,0,ZC3H8;zinc finger CCCH-type containing 8,GO:0015030//Cajal body;GO:0005634//nucleus;GO:0035327//transcriptionally active chromatin;GO:0008023//transcription elongation factor complex,"GO:0042796//snRNA transcription from RNA polymerase III promoter;GO:0043029//T cell homeostasis;GO:0046677//response to antibiotic;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0070245//positive regulation of thymocyte apoptotic process;GO:0042795//snRNA transcription from RNA polymerase II promoter;GO:0045945//positive regulation of transcription from RNA polymerase III promoter;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,K14404//Influenza A;mRNA surveillance pathway
84525,0,0,0,0,0,0,0,0,38,0,0,0,HOPX;HOP homeobox,GO:0005634//nucleus,"GO:0043393//regulation of protein binding;GO:0001829//trophectodermal cell differentiation;GO:0043415//positive regulation of skeletal muscle tissue regeneration;GO:0007507//heart development;GO:0048286//lung alveolus development;GO:0051155//positive regulation of striated muscle cell differentiation;GO:0008016//regulation of heart contraction;GO:0006351//transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0045596//negative regulation of cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding,-
84527,0,35,0,1,15,0,5,0,64,0,0,0,ZNF559;zinc finger protein 559,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84529,0,30,0,0,0,0,15,0,32,0,0,0,C15orf41;chromosome 15 open reading frame 41,-,-,-,-
8453,0,13,0,0,5,19,0,0,33,0,0,0,CUL2;cullin 2,GO:0005730//nucleolus;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0030891//VCB complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0071456//cellular response to hypoxia;GO:0007050//cell cycle arrest;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0008285//negative regulation of cell proliferation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0016567//protein ubiquitination,GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K03870//Pathways in cancer;Renal cell carcinoma;Ubiquitin mediated proteolysis
84530,128,1,10,0,0,10,0,65,51,99,0,0,SRRM4;serine/arginine repetitive matrix 4,GO:0005634//nucleus,"GO:0006397//mRNA processing;GO:0007399//nervous system development;GO:0008380//RNA splicing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0043484//regulation of RNA splicing;GO:0007605//sensory perception of sound;GO:0030154//cell differentiation",GO:0003729//mRNA binding,-
84532,0,67,1,14,63,11,54,2,53,0,0,0,ACSS1;acyl-CoA synthetase short-chain family member 1,GO:0005759//mitochondrial matrix,GO:0019427//acetyl-CoA biosynthetic process from acetate;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0006085//acetyl-CoA biosynthetic process;GO:0019413//acetate biosynthetic process;GO:0006069//ethanol oxidation;GO:0019542//propionate biosynthetic process,GO:0003987//acetate-CoA ligase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0016208//AMP binding,K01895//Microbial metabolism in diverse environments;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Methane metabolism;Glycolysis / Gluconeogenesis;Carbon fixation pathways in prokaryotes;Pyruvate metabolism;Propanoate metabolism;Metabolic pathways;Two-component system
84536,0,1,0,0,15,0,0,70,43,0,0,0,C21orf67;chromosome 21 open reading frame 67,GO:0005783//endoplasmic reticulum,-,-,-
84539,0,0,0,0,16,1,54,0,0,0,7,0,MCHR2;melanin-concentrating hormone receptor 2,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,K05054//Neuroactive ligand-receptor interaction
8454,0,26,1,0,50,0,6,0,33,0,2,0,CUL1;cullin 1,GO:0019005//SCF ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0031461//cullin-RING ubiquitin ligase complex;GO:0005829//cytosol,GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0008283//cell proliferation;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0009887//organ morphogenesis;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0008285//negative regulation of cell proliferation;GO:0097193//intrinsic apoptotic signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007219//Notch signaling pathway;GO:0007050//cell cycle arrest;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,K03347//Circadian rhythm - mammal;Ubiquitin mediated proteolysis;TGF-beta signaling pathway;Cell cycle - yeast;Cell cycle;Protein processing in endoplasmic reticulum;Herpes simplex infection;Wnt signaling pathway;Oocyte meiosis
84541,0,0,0,0,0,0,0,0,48,0,1,0,KBTBD8;kelch repeat and BTB (POZ) domain containing 8,GO:0005794//Golgi apparatus;GO:0005819//spindle,-,-,-
84542,0,82,0,29,52,12,3,0,52,0,2,0,KIAA1841;KIAA1841,-,-,-,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption
84545,0,119,105,181,182,0,33,271,33,1,556,0,MRPL43;mitochondrial ribosomal protein L43,GO:0005761//mitochondrial ribosome,GO:0006412//translation,GO:0044822//poly(A) RNA binding;GO:0003735//structural constituent of ribosome,K03946//Huntington's disease;Alzheimer's disease;Parkinson's disease;Oxidative phosphorylation;Metabolic pathways;K06521//Axon guidance
84547,0,17,0,20,0,0,1,0,21,0,0,0,PGBD1;piggyBac transposable element derived 1,GO:0016020//membrane;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006898//receptor-mediated endocytosis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005044//scavenger receptor activity,-
84548,0,28,0,0,16,0,0,0,1,4,8,0,TMEM185A;transmembrane protein 185A,GO:0016021//integral component of membrane;GO:0030425//dendrite,-,GO:0005515//protein binding,K00547//Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
84549,0,178,59,143,165,0,0,68,48,0,104,0,MAK16;MAK16 homolog (S. cerevisiae),GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
8455,83,0,0,0,0,12,81,4,43,106,0,614,ATRN;attractin,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0043473//pigmentation;GO:0006979//response to oxidative stress;GO:0042552//myelination;GO:0040014//regulation of multicellular organism growth;GO:0021549//cerebellum development;GO:0006954//inflammatory response,GO:0004872//receptor activity;GO:0030246//carbohydrate binding,K05636//Amoebiasis;Small cell lung cancer;Focal adhesion;Toxoplasmosis;Pathways in cancer;ECM-receptor interaction;K14616//Vitamin digestion and absorption
84552,0,0,1,0,15,0,0,0,30,0,1,0,PARD6G;par-6 family cell polarity regulator gamma,GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0005829//cytosol;GO:0043234//protein complex,GO:0070830//tight junction assembly;GO:0007049//cell cycle;GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0051301//cell division,GO:0005515//protein binding,K06093//Endocytosis;Tight junction
84553,41,0,1,6,0,15,21,0,104,216,16,0,FAXC;failed axon connections homolog (Drosophila),GO:0016021//integral component of membrane,-,-,-
84557,0,0,0,0,7,0,0,23,19,0,12,0,MAP1LC3A;microtubule-associated protein 1 light chain 3 alpha,GO:0005776//autophagic vacuole;GO:0000421//autophagic vacuole membrane;GO:0031410//cytoplasmic vesicle;GO:0005874//microtubule;GO:0031090//organelle membrane;GO:0005829//cytosol;GO:0005770//late endosome,GO:0000045//autophagic vacuole assembly;GO:0000422//mitochondrion degradation,GO:0008429//phosphatidylethanolamine binding;GO:0005543//phospholipid binding;GO:0005515//protein binding,-
8456,86,0,9,0,0,16,20,0,39,0,0,0,FOXN1;forkhead box N1,GO:0005634//nucleus,GO:0035878//nail development;GO:0009887//organ morphogenesis;GO:0002260//lymphocyte homeostasis;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation;GO:0033081//regulation of T cell differentiation in thymus;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0050673//epithelial cell proliferation;GO:0048538//thymus development;GO:0006952//defense response;GO:0001942//hair follicle development,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
84560,0,0,0,0,0,0,27,0,28,0,0,0,MT4;metallothionein 4,-,GO:0006875//cellular metal ion homeostasis,GO:0046872//metal ion binding,-
84561,0,0,0,0,0,0,36,36,35,0,0,0,"SLC12A8;solute carrier family 12, member 8",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006813//potassium ion transport,GO:0015293//symporter activity,-
84569,0,0,0,0,0,0,0,0,12,0,0,0,LYZL1;lysozyme-like 1,GO:0005576//extracellular region,GO:0016998//cell wall macromolecule catabolic process,GO:0003796//lysozyme activity,-
84570,117,0,0,0,9,11,70,0,65,12,0,0,"COL25A1;collagen, type XXV, alpha 1",GO:0005581//collagen trimer;GO:0005788//endoplasmic reticulum lumen;GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0030574//collagen catabolic process;GO:0022617//extracellular matrix disassembly;GO:0030198//extracellular matrix organization,GO:0008201//heparin binding;GO:0001540//beta-amyloid binding,K06237//Protein digestion and absorption;Small cell lung cancer;Amoebiasis;Focal adhesion;ECM-receptor interaction;Pathways in cancer;K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
84572,0,15,1,1,0,0,0,0,0,0,19,0,"GNPTG;N-acetylglucosamine-1-phosphate transferase, gamma subunit",GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus,GO:0016256//N-glycan processing to lysosome;GO:0046835//carbohydrate phosphorylation,GO:0042803//protein homodimerization activity,K10087//Lysosome
8458,0,0,1,0,7,31,59,11,22,44,34,0,"TTF2;transcription termination factor, RNA polymerase II",GO:0008023//transcription elongation factor complex;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm,"GO:0006369//termination of RNA polymerase II transcription;GO:0006353//DNA-templated transcription, termination;GO:0006355//regulation of transcription, DNA-templated;GO:0006397//mRNA processing;GO:0006200//ATP catabolic process;GO:0008380//RNA splicing",GO:0005524//ATP binding;GO:0008094//DNA-dependent ATPase activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008026//ATP-dependent helicase activity,-
846,75,0,0,0,12,0,0,0,14,0,23,0,CASR;calcium-sensing receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0009653//anatomical structure morphogenesis;GO:0007635//chemosensory behavior;GO:0008152//metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001503//ossification;GO:0006874//cellular calcium ion homeostasis;GO:0070509//calcium ion import;GO:0005513//detection of calcium ion,GO:0004930//G-protein coupled receptor activity;GO:0005515//protein binding;GO:0004435//phosphatidylinositol phospholipase C activity,-
8460,0,0,0,0,0,0,24,0,0,0,0,0,TPST1;tyrosylprotein sulfotransferase 1,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0006954//inflammatory response;GO:0006478//peptidyl-tyrosine sulfation,GO:0008476//protein-tyrosine sulfotransferase activity,-
84612,0,0,0,0,17,8,0,0,27,0,5,0,PARD6B;par-6 family cell polarity regulator beta,GO:0005923//tight junction;GO:0005829//cytosol;GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0043234//protein complex;GO:0045177//apical part of cell,GO:0007409//axonogenesis;GO:0070830//tight junction assembly;GO:0030334//regulation of cell migration;GO:0007049//cell cycle;GO:0007043//cell-cell junction assembly;GO:0045216//cell-cell junction organization;GO:0051301//cell division;GO:0006461//protein complex assembly;GO:0034329//cell junction assembly;GO:0007163//establishment or maintenance of cell polarity,GO:0005515//protein binding,K06093//Endocytosis;Tight junction
84614,0,0,0,0,3,0,0,0,23,28,7,0,ZBTB37;zinc finger and BTB domain containing 37,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84617,0,1,0,2,25,7,27,0,0,0,3,0,"TUBB6;tubulin, beta 6 class V",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome,GO:0051258//protein polymerization;GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0006184//GTP catabolic process;GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process,GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07375//Pathogenic Escherichia coli infection;Gap junction;Phagosome
84618,0,0,0,0,0,0,0,53,10,0,0,0,"NT5C1A;5'-nucleotidase, cytosolic IA",GO:0005829//cytosol,GO:0006195//purine nucleotide catabolic process;GO:0044281//small molecule metabolic process;GO:0009116//nucleoside metabolic process;GO:0046085//adenosine metabolic process;GO:0009128//purine nucleoside monophosphate catabolic process;GO:0006144//purine nucleobase metabolic process;GO:0016311//dephosphorylation;GO:0046135//pyrimidine nucleoside catabolic process;GO:0006206//pyrimidine nucleobase metabolic process,GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity,K01081//Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
84619,0,0,0,0,0,0,0,0,14,0,0,0,"ZGPAT;zinc finger, CCCH-type with G patch domain",GO:0005634//nucleus,"GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,-
8462,0,0,0,20,0,0,0,0,63,0,0,0,KLF11;Kruppel-like factor 11,GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043065//positive regulation of apoptotic process;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:1901653//cellular response to peptide;GO:0006915//apoptotic process,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0044212//transcription regulatory region DNA binding,-
84620,0,0,0,0,0,24,0,0,15,0,6,642,"ST6GAL2;ST6 beta-galactosamide alpha-2,6-sialyltranferase 2",GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane,GO:0097503//sialylation;GO:0007275//multicellular organismal development;GO:0040007//growth;GO:0006486//protein glycosylation;GO:0009311//oligosaccharide metabolic process,"GO:0003835//beta-galactoside alpha-2,6-sialyltransferase activity",K00779//N-Glycan biosynthesis;Metabolic pathways;Other types of O-glycan biosynthesis
84622,0,0,0,7,7,8,23,0,30,0,0,0,ZNF594;zinc finger protein 594,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84624,0,0,0,0,0,47,25,0,42,157,0,0,FNDC1;fibronectin type III domain containing 1,GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0031966//mitochondrial membrane;GO:0005911//cell-cell junction;GO:0005634//nucleus,GO:0071456//cellular response to hypoxia;GO:0001934//positive regulation of protein phosphorylation;GO:0051223//regulation of protein transport;GO:0010666//positive regulation of cardiac muscle cell apoptotic process,-,K06766//Cell adhesion molecules (CAMs)
84626,92,0,0,0,0,0,11,0,61,8,12,0,KRBA1;KRAB-A domain containing 1,-,-,-,-
84627,0,0,0,0,0,20,0,21,93,0,29,0,ZNF469;zinc finger protein 469,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,K06236//Focal adhesion;Amoebiasis;Protein digestion and absorption;ECM-receptor interaction
84628,0,12,0,0,0,0,0,38,0,0,17,655,NTNG2;netrin G2,GO:0030424//axon;GO:0046658//anchored component of plasma membrane,GO:0007409//axonogenesis,GO:0005515//protein binding,K07522//Axon guidance
84629,287,0,30,1,15,0,25,219,70,0,25,0,TNRC18;trinucleotide repeat containing 18,-,-,GO:0003682//chromatin binding,-
8463,0,0,1,2,32,29,0,0,56,0,0,0,TEAD2;TEA domain family member 2,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0035329//hippo signaling;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
84630,2,0,1,0,0,0,5,0,59,125,2,0,TTBK1;tau tubulin kinase 1,GO:0005737//cytoplasm,GO:0021762//substantia nigra development;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
84631,42,0,0,0,0,16,34,0,54,0,7,0,"SLITRK2;SLIT and NTRK-like family, member 2",GO:0016021//integral component of membrane,GO:0007409//axonogenesis,-,K06838//Axon guidance
84632,1,0,1,14,8,0,12,0,41,161,0,0,AFAP1L2;actin filament associated protein 1-like 2,GO:0005737//cytoplasm,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006954//inflammatory response;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0032757//positive regulation of interleukin-8 production;GO:0032675//regulation of interleukin-6 production;GO:0007346//regulation of mitotic cell cycle",GO:0030296//protein tyrosine kinase activator activity;GO:0042169//SH2 domain binding;GO:0017124//SH3 domain binding,-
84634,0,0,0,0,0,0,29,1,21,0,0,0,KISS1R;KISS1 receptor,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane,GO:0050482//arachidonic acid secretion;GO:0051496//positive regulation of stress fiber assembly;GO:0019722//calcium-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0000186//activation of MAPKK activity;GO:0050806//positive regulation of synaptic transmission;GO:0046887//positive regulation of hormone secretion;GO:0007218//neuropeptide signaling pathway,GO:0008188//neuropeptide receptor activity;GO:0042923//neuropeptide binding;GO:0005515//protein binding,K08374//Neuroactive ligand-receptor interaction
84636,0,0,0,0,0,27,0,0,1,0,0,0,GPR174;G protein-coupled receptor 174,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
84639,58,0,0,0,0,0,0,46,9,510,9,0,"IL1F10;interleukin 1 family, member 10 (theta)",GO:0005615//extracellular space,-,GO:0005149//interleukin-1 receptor binding;GO:0005125//cytokine activity,-
8464,23,523,391,368,843,0,36,61,18,0,1235,1,SUPT3H;suppressor of Ty 3 homolog (S. cerevisiae),GO:0030914//STAGA complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0033276//transcription factor TFTC complex,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016578//histone deubiquitination;GO:0006325//chromatin organization;GO:0043966//histone H3 acetylation;GO:0006355//regulation of transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0046982//protein heterodimerization activity,K11313//Transcriptional misregulation in cancer
84640,0,1,0,19,39,20,21,60,45,0,0,0,USP38;ubiquitin specific peptidase 38,-,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0004843//ubiquitin-specific protease activity,-
84641,83,0,0,22,15,0,20,0,39,0,0,0,HIATL1;hippocampus abundant transcript-like 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport,GO:0005215//transporter activity,K14613//Mineral absorption;Vitamin digestion and absorption
84643,99,0,0,0,0,0,0,0,38,91,0,0,KIF2B;kinesin family member 2B,GO:0000777//condensed chromosome kinetochore;GO:0005819//spindle;GO:0005871//kinesin complex;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005634//nucleus,GO:0007067//mitotic nuclear division;GO:0006200//ATP catabolic process;GO:0007019//microtubule depolymerization;GO:0007018//microtubule-based movement;GO:0051983//regulation of chromosome segregation;GO:0000278//mitotic cell cycle;GO:0008152//metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation,GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,-
84645,0,53,56,209,233,0,0,40,24,0,204,0,C22orf23;chromosome 22 open reading frame 23,-,-,-,-
84647,0,0,0,0,0,0,0,0,27,0,0,0,"PLA2G12B;phospholipase A2, group XIIB",GO:0005576//extracellular region,GO:0042632//cholesterol homeostasis;GO:0070328//triglyceride homeostasis;GO:0016042//lipid catabolic process,GO:0005509//calcium ion binding;GO:0004623//phospholipase A2 activity,K01047//Serotonergic synapse;Pancreatic secretion;alpha-Linolenic acid metabolism;GnRH signaling pathway;Glutamatergic synapse;MAPK signaling pathway;Linoleic acid metabolism;Metabolic pathways;Vascular smooth muscle contraction;Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Long-term depression;Glycerophospholipid metabolism;Ether lipid metabolism;VEGF signaling pathway;Toxoplasmosis;Arachidonic acid metabolism;Fat digestion and absorption
84649,92,0,24,6,0,7,0,0,11,150,0,0,DGAT2;diacylglycerol O-acyltransferase 2,GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0019432//triglyceride biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0042572//retinol metabolic process;GO:0019915//lipid storage;GO:0034383//low-density lipoprotein particle clearance;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0055089//fatty acid homeostasis;GO:0036155//acylglycerol acyl-chain remodeling;GO:0060613//fat pad development;GO:0097006//regulation of plasma lipoprotein particle levels;GO:0042632//cholesterol homeostasis;GO:0044281//small molecule metabolic process;GO:0071400//cellular response to oleic acid;GO:0044255//cellular lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006071//glycerol metabolic process;GO:0046339//diacylglycerol metabolic process;GO:0035356//cellular triglyceride homeostasis,GO:0042803//protein homodimerization activity;GO:0050252//retinol O-fatty-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0003846//2-acylglycerol O-acyltransferase activity,K11160//Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism
84650,0,0,1,0,1,15,0,0,0,0,0,0,EBPL;emopamil binding protein-like,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0016125//sterol metabolic process,GO:0047750//cholestenol delta-isomerase activity,K01824//Metabolic pathways;Steroid biosynthesis;Biosynthesis of secondary metabolites
84651,0,0,0,0,0,0,0,0,25,0,0,0,"SPINK7;serine peptidase inhibitor, Kazal type 7 (putative)",GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005515//protein binding,K06254//ECM-receptor interaction
84654,0,0,1,0,0,7,2,0,0,0,0,0,SPZ1;spermatogenic leucine zipper 1,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
84656,35,17,0,24,268,28,39,92,13,0,18,0,GLYR1;glyoxylate reductase 1 homolog (Arabidopsis),GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006098//pentose-phosphate shunt,GO:0004616//phosphogluconate dehydrogenase (decarboxylating) activity;GO:0051287//NAD binding;GO:0035064//methylated histone binding;GO:0003677//DNA binding,"K00020//Glutathione metabolism;Pentose phosphate pathway;Metabolic pathways;Valine, leucine and isoleucine degradation"
84658,81,0,0,0,0,14,0,59,34,0,12,0,"EMR3;egf-like module containing, mucin-like, hormone receptor-like 3",GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007218//neuropeptide signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0005509//calcium ion binding,-
84660,0,0,0,0,4,0,23,7,9,0,12,0,CCDC62;coiled-coil domain containing 62,GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0071392//cellular response to estradiol stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0030331//estrogen receptor binding,K12478//Endocytosis;Phagosome;Tuberculosis
84661,0,16,0,33,18,0,0,0,0,0,0,0,DPY30;dpy-30 homolog (C. elegans),GO:0035097//histone methyltransferase complex;GO:0005634//nucleus;GO:0048188//Set1C/COMPASS complex;GO:0005802//trans-Golgi network;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,"GO:0016197//endosomal transport;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation",GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
84662,0,36,0,0,15,9,34,0,37,1,0,0,GLIS2;GLIS family zinc finger 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck,"GO:0030154//cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045879//negative regulation of smoothened signaling pathway;GO:0007399//nervous system development;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
84665,95,0,0,0,0,36,9,0,42,0,0,0,MYPN;myopalladin,GO:0031674//I band;GO:0030018//Z disc;GO:0005634//nucleus,GO:0045214//sarcomere organization,GO:0008092//cytoskeletal protein binding;GO:0051371//muscle alpha-actinin binding;GO:0003779//actin binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
84666,0,0,39,0,0,0,0,0,0,0,0,0,RETNLB;resistin like beta,GO:0005576//extracellular region,GO:0008283//cell proliferation,GO:0005179//hormone activity,-
84667,71,0,0,0,0,0,0,0,0,0,0,0,HES7;hes family bHLH transcription factor 7,GO:0005634//nucleus,"GO:0048511//rhythmic process;GO:0014807//regulation of somitogenesis;GO:0007219//Notch signaling pathway;GO:0001756//somitogenesis;GO:0036342//post-anal tail morphogenesis;GO:0001501//skeletal system development;GO:0006351//transcription, DNA-templated;GO:0007498//mesoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0008134//transcription factor binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
84668,0,0,29,7,0,9,0,0,17,0,0,0,"FAM126A;family with sequence similarity 126, member A",GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0007165//signal transduction,GO:0004871//signal transducer activity,-
84669,168,0,1,18,52,1,102,15,73,0,0,0,USP32;ubiquitin specific peptidase 32,GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0016579//protein deubiquitination,GO:0004843//ubiquitin-specific protease activity;GO:0005509//calcium ion binding;GO:0004221//ubiquitin thiolesterase activity,-
8467,0,82,0,48,174,0,0,0,89,0,12,0,"SMARCA5;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5",GO:0031213//RSF complex;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000793//condensed chromosome;GO:0016589//NURF complex;GO:0043596//nuclear replication fork;GO:0005677//chromatin silencing complex,"GO:0006334//nucleosome assembly;GO:0006352//DNA-templated transcription, initiation;GO:0000183//chromatin silencing at rDNA;GO:0043044//ATP-dependent chromatin remodeling;GO:0006302//double-strand break repair;GO:0034080//CENP-A containing nucleosome assembly;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006200//ATP catabolic process;GO:0016584//nucleosome positioning;GO:0006338//chromatin remodeling",GO:0003677//DNA binding;GO:0004386//helicase activity;GO:0016887//ATPase activity;GO:0042393//histone binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0031491//nucleosome binding,-
84671,8,17,0,12,13,32,36,0,74,0,0,0,ZNF347;zinc finger protein 347,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84674,0,0,0,0,0,0,0,0,9,120,0,0,"CARD6;caspase recruitment domain family, member 6",-,GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process,-,K12797//NOD-like receptor signaling pathway
84675,0,0,0,0,0,14,45,0,13,0,0,0,TRIM55;tripartite motif containing 55,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0007165//signal transduction,GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0042802//identical protein binding,-
84676,25,0,0,0,0,0,8,0,11,0,0,0,"TRIM63;tripartite motif containing 63, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0031430//M band;GO:0005737//cytoplasm;GO:0030018//Z disc;GO:0005874//microtubule,GO:0014878//response to electrical stimulus involved in regulation of muscle adaptation;GO:0016567//protein ubiquitination;GO:0006936//muscle contraction;GO:0071549//cellular response to dexamethasone stimulus;GO:0010468//regulation of gene expression;GO:0007165//signal transduction;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0014732//skeletal muscle atrophy;GO:0070555//response to interleukin-1,GO:0008270//zinc ion binding;GO:0004871//signal transducer activity;GO:0031432//titin binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
84678,0,0,57,0,25,1,24,85,24,0,0,651,KDM2B;lysine (K)-specific demethylase 2B,GO:0005634//nucleus;GO:0031519//PcG protein complex;GO:0005730//nucleolus,"GO:0021993//initiation of neural tube closure;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0030900//forebrain development;GO:0021555//midbrain-hindbrain boundary morphogenesis;GO:0006351//transcription, DNA-templated;GO:2000178//negative regulation of neural precursor cell proliferation;GO:0021592//fourth ventricle development;GO:0035518//histone H2A monoubiquitination;GO:0070544//histone H3-K36 demethylation;GO:0021678//third ventricle development;GO:0007283//spermatogenesis;GO:0055114//oxidation-reduction process;GO:0021670//lateral ventricle development;GO:0048596//embryonic camera-type eye morphogenesis;GO:0030901//midbrain development;GO:0030902//hindbrain development;GO:0043524//negative regulation of neuron apoptotic process",GO:0019843//rRNA binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0032452//histone demethylase activity;GO:0008270//zinc ion binding;GO:0051864//histone demethylase activity (H3-K36 specific),-
84679,5,0,0,0,1,3,37,0,35,0,0,0,"SLC9A7;solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7",GO:0005802//trans-Golgi network;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0055038//recycling endosome membrane,GO:1902600//hydrogen ion transmembrane transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0006885//regulation of pH;GO:0071805//potassium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport,GO:0015386//potassium:proton antiporter activity;GO:0042803//protein homodimerization activity;GO:0015385//sodium:proton antiporter activity;GO:0005515//protein binding,K12041//Cardiac muscle contraction
8468,0,0,0,0,1,0,0,0,2,0,0,0,"FKBP6;FK506 binding protein 6, 36kDa",GO:0005789//endoplasmic reticulum membrane;GO:0000795//synaptonemal complex;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0031047//gene silencing by RNA;GO:0000413//protein peptidyl-prolyl isomerization;GO:0030154//cell differentiation;GO:0043046//DNA methylation involved in gamete generation;GO:0034587//piRNA metabolic process;GO:0006457//protein folding;GO:0007126//meiotic nuclear division;GO:0061077//chaperone-mediated protein folding;GO:0007283//spermatogenesis,GO:0003755//peptidyl-prolyl cis-trans isomerase activity;GO:0051879//Hsp90 protein binding;GO:0005528//FK506 binding,-
84680,0,0,0,0,0,0,0,0,3,0,9,344,ACCS;1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional),-,GO:0009058//biosynthetic process,GO:0042803//protein homodimerization activity;GO:0016847//1-aminocyclopropane-1-carboxylate synthase activity;GO:0030170//pyridoxal phosphate binding,"K00814//Metabolic pathways;Microbial metabolism in diverse environments;Alanine, aspartate and glutamate metabolism;Carbon fixation in photosynthetic organisms;K00816//Tryptophan metabolism;Selenocompound metabolism;Metabolic pathways"
84684,0,0,0,0,0,0,0,0,15,0,0,0,INSM2;insulinoma-associated 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84687,0,0,0,0,16,0,0,27,20,0,20,0,"PPP1R9B;protein phosphatase 1, regulatory subunit 9B",GO:0005886//plasma membrane;GO:0000164//protein phosphatase type 1 complex;GO:0045202//synapse;GO:0030175//filopodium;GO:0030027//lamellipodium;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0032587//ruffle membrane;GO:0005912//adherens junction;GO:0030864//cortical actin cytoskeleton,GO:0008380//RNA splicing;GO:0001932//regulation of protein phosphorylation;GO:2000474//regulation of opioid receptor signaling pathway;GO:0030308//negative regulation of cell growth;GO:0007015//actin filament organization;GO:0007096//regulation of exit from mitosis;GO:0043086//negative regulation of catalytic activity;GO:0001560//regulation of cell growth by extracellular stimulus;GO:0016358//dendrite development;GO:0007050//cell cycle arrest;GO:0071315//cellular response to morphine;GO:0046847//filopodium assembly;GO:0042127//regulation of cell proliferation;GO:0016477//cell migration;GO:0019722//calcium-mediated signaling,GO:0003779//actin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0005515//protein binding;GO:0008157//protein phosphatase 1 binding,K06095//Tight junction
84688,0,0,0,0,0,0,48,0,52,0,0,0,C9orf24;chromosome 9 open reading frame 24,GO:0002177//manchette;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0030154//cell differentiation;GO:0043623//cellular protein complex assembly;GO:0007283//spermatogenesis,GO:0043014//alpha-tubulin binding,-
84689,0,0,0,0,0,31,12,0,34,0,0,0,"MS4A14;membrane-spanning 4-domains, subfamily A, member 14",GO:0016021//integral component of membrane,-,-,K08090//Fc epsilon RI signaling pathway;Asthma;K06466//Hematopoietic cell lineage
84690,74,0,0,13,0,0,0,0,0,0,0,0,SPATA22;spermatogenesis associated 22,GO:0005694//chromosome,GO:0007129//synapsis;GO:0061458//reproductive system development;GO:0051445//regulation of meiotic cell cycle;GO:0009566//fertilization;GO:0000711//meiotic DNA repair synthesis;GO:0007276//gamete generation,-,-
84691,0,0,0,0,0,38,0,32,28,0,0,0,"FAM71F1;family with sequence similarity 71, member F1",-,-,-,-
84692,0,0,0,0,0,0,0,94,0,0,0,0,CCDC54;coiled-coil domain containing 54,-,-,-,-
84693,1,45,0,82,100,0,3,0,17,0,112,5,MCEE;methylmalonyl CoA epimerase,GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0006635//fatty acid beta-oxidation;GO:0046491//L-methylmalonyl-CoA metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019626//short-chain fatty acid catabolic process,GO:0004493//methylmalonyl-CoA epimerase activity;GO:0046872//metal ion binding,"K05606//Glyoxylate and dicarboxylate metabolism;Carbon fixation pathways in prokaryotes;Propanoate metabolism;Microbial metabolism in diverse environments;Metabolic pathways;Nucleotide excision repair;Valine, leucine and isoleucine degradation"
84694,0,0,0,0,0,0,15,0,13,0,0,0,"GJA10;gap junction protein, alpha 10, 62kDa",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005922//connexon complex,GO:0055085//transmembrane transport;GO:0007268//synaptic transmission;GO:0007276//gamete generation;GO:0007416//synapse assembly;GO:0050908//detection of light stimulus involved in visual perception,GO:0005243//gap junction channel activity,-
84695,34,57,0,54,5,9,31,34,36,129,172,0,LOXL3;lysyl oxidase-like 3,GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006898//receptor-mediated endocytosis;GO:0055114//oxidation-reduction process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001837//epithelial to mesenchymal transition",GO:0005515//protein binding;GO:0005044//scavenger receptor activity;GO:0004720//protein-lysine 6-oxidase activity;GO:0005507//copper ion binding,-
84696,0,140,83,112,185,0,0,10,27,0,51,0,ABHD1;abhydrolase domain containing 1,GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0052689//carboxylic ester hydrolase activity,-
84698,0,1,0,5,1,0,0,0,56,0,0,0,CAPS2;calcyphosine 2,-,-,GO:0005509//calcium ion binding,-
84699,0,0,0,0,0,5,0,0,24,0,0,8,CREB3L3;cAMP responsive element binding protein 3-like 3,GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein;GO:0006351//transcription, DNA-templated",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0005515//protein binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,K09048//Alcoholism;Prostate cancer;Huntington's disease;Cholinergic synapse;Dopaminergic synapse;Cocaine addiction;Melanogenesis;Vasopressin-regulated water reabsorption;Amphetamine addiction
847,0,32,1,33,163,20,0,0,41,0,0,0,CAT;catalase,GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005782//peroxisomal matrix;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005778//peroxisomal membrane;GO:0005758//mitochondrial intermembrane space;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005777//peroxisome,GO:0033197//response to vitamin E;GO:0020027//hemoglobin metabolic process;GO:0051262//protein tetramerization;GO:0043066//negative regulation of apoptotic process;GO:0008203//cholesterol metabolic process;GO:0042744//hydrogen peroxide catabolic process;GO:0051289//protein homotetramerization;GO:0042697//menopause;GO:0009650//UV protection;GO:0055093//response to hyperoxia;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0000302//response to reactive oxygen species;GO:0044281//small molecule metabolic process;GO:0001666//response to hypoxia;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling;GO:0009060//aerobic respiration;GO:0006144//purine nucleobase metabolic process;GO:0006641//triglyceride metabolic process;GO:0071363//cellular response to growth factor stimulus;GO:0051781//positive regulation of cell division;GO:0001649//osteoblast differentiation;GO:0006195//purine nucleotide catabolic process;GO:0001657//ureteric bud development;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0004096//catalase activity;GO:0005102//receptor binding;GO:0004046//aminoacylase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0020037//heme binding;GO:0019899//enzyme binding;GO:0050661//NADP binding;GO:0016209//antioxidant activity,K03781//Biosynthesis of secondary metabolites;Methane metabolism;Peroxisome;Tryptophan metabolism;MAPK signaling pathway - yeast;Microbial metabolism in diverse environments;Histidine metabolism;Glyoxylate and dicarboxylate metabolism;Amyotrophic lateral sclerosis (ALS);Metabolic pathways
8470,138,28,1,35,93,40,15,67,35,143,14,0,SORBS2;sorbin and SH3 domain containing 2,GO:0005886//plasma membrane;GO:0015629//actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0030018//Z disc,GO:0007015//actin filament organization;GO:0007155//cell adhesion;GO:0016477//cell migration,GO:0005200//structural constituent of cytoskeleton;GO:0008307//structural constituent of muscle;GO:0019904//protein domain specific binding;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0008093//cytoskeletal adaptor activity;GO:0005515//protein binding,K06086//Adherens junction;Insulin signaling pathway;PPAR signaling pathway
84700,0,0,0,0,0,17,1,72,62,0,8,0,MYO18B;myosin XVIIIB,GO:0016461//unconventional myosin complex;GO:0030017//sarcomere;GO:0005634//nucleus,GO:0008152//metabolic process,GO:0003774//motor activity;GO:0005524//ATP binding;GO:0003779//actin binding,-
84701,0,0,0,0,0,0,0,0,14,0,8,0,COX4I2;cytochrome c oxidase subunit IV isoform 2 (lung),GO:0005751//mitochondrial respiratory chain complex IV,GO:0055114//oxidation-reduction process;GO:0006091//generation of precursor metabolites and energy;GO:0045333//cellular respiration;GO:1902600//hydrogen ion transmembrane transport,GO:0004129//cytochrome-c oxidase activity,K02263//Cardiac muscle contraction;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation;Metabolic pathways
84705,0,0,0,0,1,0,0,0,13,0,0,0,GTPBP3;GTP binding protein 3 (mitochondrial),GO:0005634//nucleus;GO:0005739//mitochondrion,GO:0006184//GTP catabolic process;GO:0006400//tRNA modification,GO:0003924//GTPase activity;GO:0005525//GTP binding,-
84706,0,31,0,39,45,48,22,0,1,68,0,0,GPT2;glutamic pyruvate transaminase (alanine aminotransferase) 2,GO:0005759//mitochondrial matrix,GO:0008652//cellular amino acid biosynthetic process;GO:0006103//2-oxoglutarate metabolic process;GO:0044281//small molecule metabolic process;GO:0042853//L-alanine catabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0004021//L-alanine:2-oxoglutarate aminotransferase activity;GO:0030170//pyridoxal phosphate binding,"K00814//Carbon fixation in photosynthetic organisms;Metabolic pathways;Microbial metabolism in diverse environments;Alanine, aspartate and glutamate metabolism"
84707,0,0,0,7,28,0,0,0,8,0,4,0,BEX2;brain expressed X-linked 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051726//regulation of cell cycle;GO:0007049//cell cycle;GO:0042981//regulation of apoptotic process;GO:0006915//apoptotic process,-,K12465//Neurotrophin signaling pathway
84708,217,32,0,33,27,0,30,1,12,0,18,1,"LNX1;ligand of numb-protein X 1, E3 ubiquitin protein ligase",GO:0005737//cytoplasm,GO:0051260//protein homooligomerization;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0030165//PDZ domain binding,-
84709,0,0,0,0,0,42,0,0,27,0,0,0,MGARP;mitochondria-localized glutamic acid-rich protein,GO:0005739//mitochondrion;GO:0031307//integral component of mitochondrial outer membrane,GO:0008089//anterograde axon cargo transport;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:0071456//cellular response to hypoxia;GO:0008090//retrograde axon cargo transport;GO:0019896//axon transport of mitochondrion;GO:0071383//cellular response to steroid hormone stimulus;GO:0006626//protein targeting to mitochondrion;GO:0010822//positive regulation of mitochondrion organization,GO:0005515//protein binding,K04727//Apoptosis
8471,160,0,0,0,0,0,6,0,23,50,0,0,IRS4;insulin receptor substrate 4,GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity;GO:0005158//insulin receptor binding;GO:0004871//signal transducer activity;GO:0005515//protein binding,K07187//Type II diabetes mellitus;Aldosterone-regulated sodium reabsorption;Neurotrophin signaling pathway;Insulin signaling pathway;Adipocytokine signaling pathway
84717,0,0,1,0,4,10,0,0,6,0,1,0,HDGFRP2;hepatoma-derived growth factor-related protein 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,-
84720,0,0,0,2,0,0,0,0,1,8,5,0,"PIGO;phosphatidylinositol glycan anchor biosynthesis, class O",GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation;GO:0016254//preassembly of GPI anchor in ER membrane;GO:0043687//post-translational protein modification;GO:0006506//GPI anchor biosynthetic process,GO:0016740//transferase activity,K05288//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
84722,0,0,0,0,6,3,0,0,19,0,11,0,PSRC1;proline/serine-rich coiled-coil 1,GO:0005819//spindle;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005876//spindle microtubule;GO:0000922//spindle pole;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus,"GO:0001578//microtubule bundle formation;GO:0007080//mitotic metaphase plate congression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0031116//positive regulation of microtubule polymerization;GO:0060236//regulation of mitotic spindle organization;GO:0030308//negative regulation of cell growth",GO:0008017//microtubule binding;GO:0005515//protein binding,K10129//p53 signaling pathway
84725,177,0,0,0,1,0,0,0,35,0,0,0,"PLEKHA8;pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8",GO:0016020//membrane;GO:0005802//trans-Golgi network,GO:0015031//protein transport;GO:0006869//lipid transport;GO:0035621//ER to Golgi ceramide transport;GO:0046836//glycolipid transport,GO:0051861//glycolipid binding;GO:0097001//ceramide binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0017089//glycolipid transporter activity,-
84726,0,2,0,6,120,66,0,43,47,0,30,0,PRRC2B;proline-rich coiled-coil 2B,-,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
84727,0,0,0,14,1,0,0,6,2,0,0,0,SPSB2;splA/ryanodine receptor domain and SOCS box containing 2,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,GO:0005515//protein binding,-
8473,0,0,0,54,37,0,0,0,16,0,4,308,OGT;O-linked N-acetylglucosamine (GlcNAc) transferase,GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0070688//MLL5-L complex;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0000123//histone acetyltransferase complex;GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0046626//regulation of insulin receptor signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0006493//protein O-linked glycosylation;GO:0045862//positive regulation of proteolysis;GO:0007584//response to nutrient;GO:0043085//positive regulation of catalytic activity;GO:0071300//cellular response to retinoic acid;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0006915//apoptotic process;GO:0043984//histone H4-K16 acetylation;GO:0007165//signal transduction;GO:0061087//positive regulation of histone H3-K27 methylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006110//regulation of glycolytic process;GO:0048015//phosphatidylinositol-mediated signaling;GO:0006325//chromatin organization;GO:0090526//regulation of gluconeogenesis involved in cellular glucose homeostasis;GO:0032922//circadian regulation of gene expression;GO:0043981//histone H4-K5 acetylation;GO:0080182//histone H3-K4 trimethylation;GO:0035020//regulation of Rac protein signal transduction;GO:0032868//response to insulin;GO:0043982//histone H4-K8 acetylation;GO:0030854//positive regulation of granulocyte differentiation,"GO:0046972//histone acetyltransferase activity (H4-K16 specific);GO:0043995//histone acetyltransferase activity (H4-K5 specific);GO:0016262//protein N-acetylglucosaminyltransferase activity;GO:0005515//protein binding;GO:0043996//histone acetyltransferase activity (H4-K8 specific);GO:0097363//protein O-GlcNAc transferase activity;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008047//enzyme activator activity;GO:0008375//acetylglucosaminyltransferase activity",K09667//Other types of O-glycan biosynthesis
84733,0,33,0,0,0,0,3,0,29,0,0,0,CBX2;chromobox homolog 2,GO:0005730//nucleolus;GO:0035102//PRC1 complex;GO:0031519//PcG protein complex;GO:0000792//heterochromatin;GO:0000791//euchromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0045137//development of primary sexual characteristics;GO:0030154//cell differentiation;GO:0016568//chromatin modification;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0035064//methylated histone binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0003682//chromatin binding,-
84734,0,0,0,0,0,0,0,52,0,0,0,0,"FAM167B;family with sequence similarity 167, member B",-,-,-,-
84735,0,0,0,0,0,0,4,56,7,0,0,0,CNDP1;carnosine dipeptidase 1 (metallopeptidase M20 family),GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0004180//carboxypeptidase activity;GO:0034701//tripeptidase activity;GO:0016805//dipeptidase activity;GO:0008237//metallopeptidase activity;GO:0046872//metal ion binding,K05604//Arginine and proline metabolism;beta-Alanine metabolism;Metabolic pathways;Histidine metabolism
84740,107,94,284,141,119,0,65,517,265,2,260,643,AFAP1-AS1;AFAP1 antisense RNA 1,-,-,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
84747,92,81,0,42,63,0,0,0,13,0,0,0,UNC119B;unc-119 homolog B (C. elegans),GO:0035869//ciliary transition zone,GO:0060271//cilium morphogenesis;GO:0042953//lipoprotein transport,GO:0005515//protein binding;GO:0008289//lipid binding,-
84750,78,0,0,0,9,12,0,16,31,0,0,0,"FUT10;fucosyltransferase 10 (alpha (1,3) fucosyltransferase)",GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0005794//Golgi apparatus,GO:0042060//wound healing;GO:0030097//hemopoiesis;GO:0006457//protein folding;GO:0042355//L-fucose catabolic process;GO:0007399//nervous system development;GO:0006605//protein targeting;GO:0009566//fertilization;GO:0009790//embryo development;GO:0006486//protein glycosylation;GO:0036065//fucosylation,GO:0046920//alpha-(1->3)-fucosyltransferase activity,-
84752,0,0,52,35,86,2,2,0,4,0,54,0,"B3GNT9;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006486//protein glycosylation,GO:0008378//galactosyltransferase activity,K09664//Glycosaminoglycan biosynthesis - keratan sulfate
84759,0,0,0,0,1,0,0,0,0,0,0,0,PCGF1;polycomb group ring finger 1,GO:0005634//nucleus;GO:0031519//PcG protein complex;GO:0005730//nucleolus,"GO:0035518//histone H2A monoubiquitination;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
8476,56,59,3,114,214,8,36,64,114,262,0,0,CDC42BPA;CDC42 binding protein kinase alpha (DMPK-like),GO:0042641//actomyosin;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge,GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0050790//regulation of catalytic activity;GO:0007097//nuclear migration;GO:0035556//intracellular signal transduction;GO:0031532//actin cytoskeleton reorganization;GO:0000226//microtubule cytoskeleton organization;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0042802//identical protein binding,-
84765,0,0,0,12,14,0,11,0,15,0,12,0,ZNF577;zinc finger protein 577,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84766,92,27,0,4,22,34,20,0,14,71,11,0,CRACR2A;calcium release activated channel regulator 2A,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0002115//store-operated calcium entry;GO:0051928//positive regulation of calcium ion transport;GO:0002376//immune system process;GO:0032237//activation of store-operated calcium channel activity,GO:0005509//calcium ion binding;GO:0005515//protein binding,K06109//Tight junction
84767,0,0,0,0,0,0,0,0,19,0,0,0,TRIM51;tripartite motif-containing 51,GO:0005622//intracellular,-,GO:0008270//zinc ion binding,-
84769,0,0,0,0,1,17,0,0,22,0,0,0,MPV17L2;MPV17 mitochondrial membrane protein-like 2,GO:0005739//mitochondrion;GO:0016021//integral component of membrane,-,-,K13348//Peroxisome
8477,0,0,0,9,0,7,23,0,0,0,16,0,GPR65;G protein-coupled receptor 65,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0010447//response to acidic pH;GO:0051496//positive regulation of stress fiber assembly;GO:0031532//actin cytoskeleton reorganization;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007275//multicellular organismal development;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0032862//activation of Rho GTPase activity;GO:0006915//apoptotic process;GO:0006955//immune response,GO:0004930//G-protein coupled receptor activity,-
84775,0,61,12,0,3,0,2,66,28,0,10,0,ZNF607;zinc finger protein 607,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84779,0,0,0,0,0,0,27,0,0,0,6,0,"NAA11;N(alpha)-acetyltransferase 11, NatA catalytic subunit",GO:0005634//nucleus;GO:0031415//NatA complex,GO:0006474//N-terminal protein amino acid acetylation,GO:0005515//protein binding;GO:0004596//peptide alpha-N-acetyltransferase activity,K00864//Plant-pathogen interaction;PPAR signaling pathway;Glycerolipid metabolism;Metabolic pathways
84787,53,0,0,0,0,0,3,0,23,0,3,0,SUV420H2;suppressor of variegation 4-20 homolog 2 (Drosophila),"GO:0005730//nucleolus;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0005720//nuclear heterochromatin;GO:0005634//nucleus","GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0034773//histone H4-K20 trimethylation",GO:0042799//histone methyltransferase activity (H4-K20 specific);GO:0005515//protein binding,K11429//Lysine degradation
8479,0,0,0,12,0,25,0,0,54,0,16,0,HIRIP3;HIRA interacting protein 3,GO:0005634//nucleus,GO:0006333//chromatin assembly or disassembly,GO:0005515//protein binding,-
84790,0,0,0,1,47,0,0,0,7,0,1,0,"TUBA1C;tubulin, alpha 1c",GO:0005634//nucleus;GO:0031982//vesicle;GO:0005874//microtubule;GO:0005881//cytoplasmic microtubule,GO:0051301//cell division;GO:0051084//'de novo' posttranslational protein folding;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0051258//protein polymerization;GO:0006184//GTP catabolic process;GO:0006457//protein folding;GO:0044267//cellular protein metabolic process;GO:0007017//microtubule-based process,GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0005200//structural constituent of cytoskeleton;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07374//Gap junction;Phagosome;Pathogenic Escherichia coli infection
84792,0,0,3,0,1,0,0,0,2,0,0,0,"FAM220A;family with sequence similarity 220, member A",GO:0005634//nucleus,-,-,-
84795,0,0,0,0,0,0,18,0,23,0,0,0,PYROXD2;pyridine nucleotide-disulphide oxidoreductase domain 2,-,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K09516//Retinol metabolism
84798,5,0,1,2,4,0,0,0,0,0,0,0,C19orf48;chromosome 19 open reading frame 48,-,-,-,K00797//beta-Alanine metabolism;Metabolic pathways;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism
8480,0,0,0,3,26,0,0,0,17,0,0,0,RAE1;ribonucleic acid export 1,GO:0005730//nucleolus;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005635//nuclear envelope;GO:0005737//cytoplasm;GO:0005640//nuclear outer membrane;GO:0005643//nuclear pore,GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0071407//cellular response to organic cyclic compound;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0006406//mRNA export from nucleus;GO:0005975//carbohydrate metabolic process;GO:0010827//regulation of glucose transport,GO:0008017//microtubule binding;GO:0003723//RNA binding,K14298//Influenza A;RNA transport
84803,0,0,0,0,0,0,0,0,23,74,0,0,AGPAT9;1-acylglycerol-3-phosphate O-acyltransferase 9,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044255//cellular lipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006654//phosphatidic acid biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0032006//regulation of TOR signaling,GO:0004366//glycerol-3-phosphate O-acyltransferase activity;GO:0003841//1-acylglycerol-3-phosphate O-acyltransferase activity,K13506//Glycerophospholipid metabolism;Glycerolipid metabolism;Metabolic pathways
84804,0,0,0,0,0,0,0,62,33,0,0,0,MFSD9;major facilitator superfamily domain containing 9,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,GO:0005215//transporter activity,K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism
84807,0,0,0,0,0,0,0,0,14,0,0,0,"NFKBID;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta",GO:0005634//nucleus,GO:0070245//positive regulation of thymocyte apoptotic process;GO:0033085//negative regulation of T cell differentiation in thymus;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006954//inflammatory response;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0051059//NF-kappaB binding,-
84808,0,2,0,0,9,44,0,0,23,0,18,0,"PERM1;PPARGC1 and ESRR induced regulator, muscle 1",GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0014850//response to muscle activity;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,K04632//Gastric acid secretion;Melanogenesis;Vibrio cholerae infection;Bile secretion;Chagas disease (American trypanosomiasis);Long-term depression;Dilated cardiomyopathy;Calcium signaling pathway;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Taste transduction;Amphetamine addiction;Glutamatergic synapse;Vascular smooth muscle contraction;Vasopressin-regulated water reabsorption;Morphine addiction;Amoebiasis;GnRH signaling pathway;Gap junction;Cocaine addiction;Dopaminergic synapse;Serotonergic synapse;Alcoholism;Pancreatic secretion;K06261//ECM-receptor interaction;Hematopoietic cell lineage;K14307//RNA transport
84809,74,0,0,0,0,18,64,9,67,0,10,4,"CROCCP2;ciliary rootlet coiled-coil, rootletin pseudogene 2",-,-,-,-
8481,0,27,1,1,28,0,10,0,17,0,0,0,OFD1;oral-facial-digital syndrome 1,GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005929//cilium;GO:0005829//cytosol;GO:0005814//centriole;GO:0034451//centriolar satellite;GO:0005813//centrosome;GO:0036064//ciliary basal body;GO:0016020//membrane,GO:2000314//negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0090307//spindle assembly involved in mitosis;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0060287//epithelial cilium movement involved in determination of left/right asymmetry;GO:0035082//axoneme assembly;GO:0007067//mitotic nuclear division;GO:0060271//cilium morphogenesis;GO:0010172//embryonic body morphogenesis,GO:0043015//gamma-tubulin binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding,K04514//Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Focal adhesion;Chemokine signaling pathway;Axon guidance;Salmonella infection;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
84811,0,0,0,4,0,13,19,0,7,0,0,0,BUD13;BUD13 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0070274//RES complex,"GO:0000398//mRNA splicing, via spliceosome;GO:0006406//mRNA export from nucleus",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
84812,60,0,40,27,37,0,39,42,28,0,59,307,"PLCD4;phospholipase C, delta 4",GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005634//nucleus,GO:0046488//phosphatidylinositol metabolic process;GO:0016042//lipid catabolic process;GO:0007340//acrosome reaction;GO:0035556//intracellular signal transduction,GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:0004435//phosphatidylinositol phospholipase C activity,K05857//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism;Calcium signaling pathway
84814,0,0,0,0,0,0,0,0,17,0,0,0,PPAPDC3;phosphatidic acid phosphatase type 2 domain containing 3,GO:0005635//nuclear envelope;GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0010832//negative regulation of myotube differentiation;GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
84815,0,0,0,0,0,0,2,0,0,0,0,0,MGC12916;uncharacterized protein MGC12916,-,-,-,-
84816,0,1,0,12,32,7,0,0,10,0,0,0,RTN4IP1;reticulon 4 interacting protein 1,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity;GO:0008270//zinc ion binding,K00344//Microbial metabolism in diverse environments;Glycolysis / Gluconeogenesis;Biosynthesis of secondary metabolites;Naphthalene degradation;Metabolic pathways;Tyrosine metabolism;Fatty acid metabolism;Chloroalkane and chloroalkene degradation;K10133//p53 signaling pathway
84817,0,34,24,96,188,10,25,0,24,0,44,0,TXNDC17;thioredoxin domain containing 17,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0055114//oxidation-reduction process,GO:0004601//peroxidase activity;GO:0005515//protein binding;GO:0047134//protein-disulfide reductase activity;GO:0009055//electron carrier activity,K00771//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
84818,0,1,1,2,10,0,0,387,12,0,42,0,IL17RC;interleukin 17 receptor C,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:1900017//positive regulation of cytokine production involved in inflammatory response;GO:0019221//cytokine-mediated signaling pathway,GO:0030368//interleukin-17 receptor activity,-
8482,38,0,0,0,0,0,0,0,69,11,0,0,"SEMA7A;semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)",GO:0031225//anchored component of membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016020//membrane,GO:0007229//integrin-mediated signaling pathway;GO:0006954//inflammatory response;GO:0001649//osteoblast differentiation;GO:0060907//positive regulation of macrophage cytokine production;GO:0021988//olfactory lobe development;GO:0001934//positive regulation of protein phosphorylation;GO:0045773//positive regulation of axon extension;GO:0007411//axon guidance;GO:0006955//immune response;GO:0050727//regulation of inflammatory response;GO:0048675//axon extension;GO:0070374//positive regulation of ERK1 and ERK2 cascade,GO:0004872//receptor activity;GO:0005178//integrin binding;GO:0005515//protein binding,K06529//Axon guidance
84820,3,577,155,575,763,13,38,214,81,0,929,0,"POLR2J4;polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene",-,-,-,K03008//Huntington's disease;Metabolic pathways;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Pyrimidine metabolism
84823,0,0,2,0,3,18,3,37,44,0,0,1,LMNB2;lamin B2,GO:0005637//nuclear inner membrane;GO:0005638//lamin filament,-,GO:0005198//structural molecule activity,-
84824,0,0,0,0,0,28,69,0,15,0,0,0,FCRLA;Fc receptor-like A,GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0030154//cell differentiation,-,K06498//Systemic lupus erythematosus;Leishmaniasis;Osteoclast differentiation;Staphylococcus aureus infection;Hematopoietic cell lineage;Phagosome;Transcriptional misregulation in cancer;Tuberculosis;Fc gamma R-mediated phagocytosis;K06472//Fc gamma R-mediated phagocytosis;Tuberculosis;Systemic lupus erythematosus;Leishmaniasis;Osteoclast differentiation;Staphylococcus aureus infection;Phagosome
84826,0,3,0,34,16,0,1,350,40,0,62,513,SFT2D3;SFT2 domain containing 3,GO:0016021//integral component of membrane,GO:0016192//vesicle-mediated transport;GO:0015031//protein transport,-,-
8483,93,0,0,0,9,31,12,0,1,0,27,234,"CILP;cartilage intermediate layer protein, nucleotide pyrophosphohydrolase",GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0043569//negative regulation of insulin-like growth factor receptor signaling pathway,GO:0004035//alkaline phosphatase activity;GO:0004551//nucleotide diphosphatase activity,K06841//Axon guidance;K13908//Salivary secretion;K03544//Cell cycle - Caulobacter
84830,0,0,0,0,0,24,0,0,14,0,0,0,ADTRP;androgen-dependent TFPI-regulating protein,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,-
84832,0,1,8,94,71,0,0,0,39,0,29,0,ANKRD36BP1;ankyrin repeat domain 36B pseudogene 1,-,-,-,-
84833,0,16,0,53,88,0,0,0,5,39,0,0,USMG5;up-regulated during skeletal muscle growth 5 homolog (mouse),GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005753//mitochondrial proton-transporting ATP synthase complex,-,-,-
84836,0,0,43,1,47,0,0,0,17,0,4,0,ABHD14B;abhydrolase domain containing 14B,GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0008152//metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0016787//hydrolase activity,-
84838,1,0,0,0,8,82,22,0,23,231,0,0,ZNF496;zinc finger protein 496,GO:0005634//nucleus;GO:0016604//nuclear body,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0003677//DNA binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
84839,0,0,0,0,0,14,27,44,17,0,0,197,RAX2;retina and anterior neural fold homeobox 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0007601//visual perception;GO:0006355//regulation of transcription, DNA-templated;GO:0050896//response to stimulus",GO:0043565//sequence-specific DNA binding,-
84842,0,0,3,0,0,0,0,73,0,0,2,0,HPDL;4-hydroxyphenylpyruvate dioxygenase-like,-,GO:0009072//aromatic amino acid family metabolic process;GO:0055114//oxidation-reduction process,GO:0046872//metal ion binding;GO:0003868//4-hydroxyphenylpyruvate dioxygenase activity,K00457//Phenylalanine metabolism;Ubiquinone and other terpenoid-quinone biosynthesis;Tyrosine metabolism;Metabolic pathways
84844,0,0,0,0,31,0,0,0,2,0,0,0,PHF5A;PHD finger protein 5A,GO:0016607//nuclear speck;GO:0005689//U12-type spliceosomal complex;GO:0005686//U2 snRNP;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0010467//gene expression",GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K12834//Spliceosome
84851,0,18,19,7,61,0,2,0,15,0,8,0,TRIM52;tripartite motif containing 52,GO:0005622//intracellular,GO:0051092//positive regulation of NF-kappaB transcription factor activity,GO:0008270//zinc ion binding,-
84858,66,0,0,2,8,0,0,0,12,0,15,0,ZNF503;zinc finger protein 503,GO:0005634//nucleus,"GO:0010629//negative regulation of gene expression;GO:0070315//G1 to G0 transition involved in cell differentiation;GO:0006351//transcription, DNA-templated;GO:0061351//neural precursor cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
84859,0,0,0,6,15,0,0,1,0,0,0,79,LRCH3;leucine-rich repeats and calponin homology (CH) domain containing 3,GO:0005737//cytoplasm;GO:0005576//extracellular region,-,-,K10130//NF-kappa B signaling pathway;p53 signaling pathway
84861,0,0,0,11,0,0,0,0,0,0,0,0,KLHL22;kelch-like family member 22,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0072686//mitotic spindle;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005827//polar microtubule,GO:0051301//cell division;GO:0007094//mitotic spindle assembly checkpoint;GO:0000070//mitotic sister chromatid segregation;GO:0006513//protein monoubiquitination,GO:0005515//protein binding,-
84864,0,962,554,2633,2342,0,59,77,48,126,1457,2,MINA;MYC induced nuclear antigen,GO:0005667//transcription factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0055114//oxidation-reduction process;GO:0042254//ribosome biogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0046872//metal ion binding;GO:0051213//dioxygenase activity;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription,-
84865,0,14,0,11,1,0,0,0,99,0,23,8,CCDC142;coiled-coil domain containing 142,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
84866,0,0,0,0,0,18,0,0,6,0,0,0,TMEM25;transmembrane protein 25,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
84867,256,0,0,0,0,0,44,45,39,0,6,1,"PTPN5;protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0004725//protein tyrosine phosphatase activity;GO:0001784//phosphotyrosine binding,K04458//MAPK signaling pathway
84868,0,0,0,0,0,0,16,38,0,0,0,0,HAVCR2;hepatitis A virus cellular receptor 2,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
84869,0,24,0,0,26,5,0,0,19,0,0,0,CBR4;carbonyl reductase 4,GO:0005759//mitochondrial matrix,GO:0044598//doxorubicin metabolic process;GO:0055114//oxidation-reduction process;GO:0044597//daunorubicin metabolic process;GO:0051289//protein homotetramerization;GO:0006633//fatty acid biosynthetic process,GO:0003955//NAD(P)H dehydrogenase (quinone) activity;GO:0005515//protein binding;GO:0008753//NADPH dehydrogenase (quinone) activity;GO:0048038//quinone binding;GO:0070402//NADPH binding,-
8487,0,0,0,0,0,0,39,0,0,0,0,0,GEMIN2;gem (nuclear organelle) associated protein 2,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0005654//nucleoplasm;GO:0005681//spliceosomal complex;GO:0097504//Gemini of coiled bodies;GO:0034719//SMN-Sm protein complex,"GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0000375//RNA splicing, via transesterification reactions;GO:0000245//spliceosomal complex assembly;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0016070//RNA metabolic process",GO:0005515//protein binding,K13130//RNA transport
84870,0,0,0,0,0,0,0,0,31,0,0,0,RSPO3;R-spondin 3,GO:0005576//extracellular region,GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060070//canonical Wnt signaling pathway,GO:0005109//frizzled binding;GO:0005102//receptor binding;GO:0008201//heparin binding,-
84871,0,0,0,0,0,14,0,1,72,36,3,0,AGBL4;ATP/GTP binding protein-like 4,GO:0005829//cytosol,GO:0035609//C-terminal protein deglutamylation;GO:0006508//proteolysis;GO:0035610//protein side chain deglutamylation,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity;GO:0015631//tubulin binding,K02999//RNA polymerase;Purine metabolism;Pyrimidine metabolism;Metabolic pathways
84872,0,0,1,0,14,0,0,0,11,0,0,0,ZC3H10;zinc finger CCCH-type containing 10,-,-,GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
84873,0,0,0,0,0,0,19,0,4,0,0,0,GPR128;G protein-coupled receptor 128,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007218//neuropeptide signaling pathway;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
84874,0,16,0,1,26,15,0,0,65,0,4,0,ZNF514;zinc finger protein 514,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84875,0,0,0,3,1,13,0,0,15,47,7,0,"PARP10;poly (ADP-ribose) polymerase family, member 10",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005794//Golgi apparatus,"GO:0006471//protein ADP-ribosylation;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:1900045//negative regulation of protein K63-linked ubiquitination;GO:0010847//regulation of chromatin assembly;GO:0010629//negative regulation of gene expression;GO:0033159//negative regulation of protein import into nucleus, translocation;GO:0070212//protein poly-ADP-ribosylation;GO:0048147//negative regulation of fibroblast proliferation;GO:0045071//negative regulation of viral genome replication;GO:0070213//protein auto-ADP-ribosylation",GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0070530//K63-linked polyubiquitin binding,-
84876,0,0,0,0,0,0,0,18,0,0,0,0,ORAI1;ORAI calcium release-activated calcium modulator 1,GO:0016020//membrane;GO:0043234//protein complex;GO:0005887//integral component of plasma membrane,GO:0070588//calcium ion transmembrane transport;GO:0051924//regulation of calcium ion transport;GO:0002376//immune system process;GO:0007596//blood coagulation;GO:0051928//positive regulation of calcium ion transport;GO:0002115//store-operated calcium entry,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0015279//store-operated calcium channel activity;GO:0005516//calmodulin binding,K16056//Primary immunodeficiency;Calcium signaling pathway
84878,0,29,0,25,4,0,0,0,22,0,51,0,ZBTB45;zinc finger and BTB domain containing 45,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84879,0,0,0,0,0,0,0,0,18,0,0,0,MFSD2A;major facilitator superfamily domain containing 2A,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane,GO:0015908//fatty acid transport;GO:0060856//establishment of blood-brain barrier;GO:0055085//transmembrane transport;GO:0015914//phospholipid transport;GO:1990379//lipid transport across blood brain barrier;GO:0045056//transcytosis,GO:0005548//phospholipid transporter activity;GO:0015293//symporter activity,-
84881,0,0,0,0,0,0,45,58,31,0,0,0,RPUSD4;RNA pseudouridylate synthase domain containing 4,GO:0005739//mitochondrion,GO:0001522//pseudouridine synthesis,GO:0009982//pseudouridine synthase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K01718//Pyrimidine metabolism;K13984//Protein processing in endoplasmic reticulum
84883,14,0,0,7,1,0,25,20,14,127,4,0,"AIFM2;apoptosis-inducing factor, mitochondrion-associated, 2",GO:0005737//cytoplasm;GO:0005811//lipid particle;GO:0005829//cytosol;GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005741//mitochondrial outer membrane,GO:0043065//positive regulation of apoptotic process;GO:0008637//apoptotic mitochondrial changes;GO:0055114//oxidation-reduction process,GO:0050660//flavin adenine dinucleotide binding;GO:0008137//NADH dehydrogenase (ubiquinone) activity;GO:0004174//electron-transferring-flavoprotein dehydrogenase activity;GO:0003677//DNA binding,K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
84885,0,0,0,0,4,0,0,0,0,0,0,0,"ZDHHC12;zinc finger, DHHC-type containing 12",GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0018345//protein palmitoylation,GO:0019706//protein-cysteine S-palmitoyltransferase activity;GO:0016409//palmitoyltransferase activity;GO:0008270//zinc ion binding,-
84886,0,2,1,35,62,0,19,31,1,0,1,0,C1orf198;chromosome 1 open reading frame 198,GO:0005737//cytoplasm,-,-,K09821//Renin-angiotensin system
84888,0,0,0,0,10,0,0,0,31,0,0,0,SPPL2A;signal peptide peptidase like 2A,GO:0071458//integral component of cytoplasmic side of endoplasmic reticulum membrane;GO:0030660//Golgi-associated vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0050776//regulation of immune response;GO:0006509//membrane protein ectodomain proteolysis;GO:0031293//membrane protein intracellular domain proteolysis,GO:0004190//aspartic-type endopeptidase activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
84889,0,0,0,0,0,24,0,0,4,0,0,0,"SLC7A3;solute carrier family 7 (cationic amino acid transporter, y+ system), member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0015809//arginine transport;GO:0015819//lysine transport;GO:0006865//amino acid transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0006811//ion transport,GO:0015189//L-lysine transmembrane transporter activity;GO:0015181//arginine transmembrane transporter activity,-
84890,78,1,0,2,9,0,7,2,33,0,0,0,ADO;2-aminoethanethiol (cysteamine) dioxygenase,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0047800//cysteamine dioxygenase activity;GO:0046872//metal ion binding,K10712//Metabolic pathways;Taurine and hypotaurine metabolism
84891,0,0,0,0,0,15,16,0,15,0,0,0,ZSCAN10;zinc finger and SCAN domain containing 10,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
84892,93,0,0,0,0,0,0,28,12,0,0,0,"POMGNT2;protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)",GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006493//protein O-linked glycosylation,GO:0008375//acetylglucosaminyltransferase activity;GO:0097363//protein O-GlcNAc transferase activity,-
84893,0,77,52,16,32,22,9,518,61,0,39,0,"FBXO18;F-box protein, helicase, 18",GO:0005634//nucleus,"GO:0032508//DNA duplex unwinding;GO:1902231//positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001934//positive regulation of protein phosphorylation;GO:0000737//DNA catabolic process, endonucleolytic",GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0003677//DNA binding;GO:0005515//protein binding,-
84894,0,0,0,0,0,0,39,0,0,0,0,0,LINGO1;leucine rich repeat and Ig domain containing 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0050770//regulation of axonogenesis;GO:0048715//negative regulation of oligodendrocyte differentiation;GO:0050771//negative regulation of axonogenesis;GO:0031175//neuron projection development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0021954//central nervous system neuron development;GO:0043491//protein kinase B signaling,GO:0005154//epidermal growth factor receptor binding,K07523//Axon guidance
84895,0,0,0,0,1,21,15,30,20,133,0,0,"FAM73B;family with sequence similarity 73, member B",GO:0016021//integral component of membrane,GO:0060348//bone development,-,-
84896,0,0,1,32,37,8,21,0,24,0,0,0,"ATAD1;ATPase family, AAA domain containing 1",GO:0005739//mitochondrion;GO:0045211//postsynaptic membrane;GO:0016020//membrane;GO:0030054//cell junction;GO:0005778//peroxisomal membrane,"GO:0007612//learning;GO:0006200//ATP catabolic process;GO:0051967//negative regulation of synaptic transmission, glutamatergic;GO:0007613//memory;GO:0002092//positive regulation of receptor internalization",GO:0016887//ATPase activity;GO:0005524//ATP binding,-
84897,0,1,0,46,42,13,0,56,34,0,0,2,TBRG1;transforming growth factor beta regulator 1,GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus,GO:0006260//DNA replication;GO:0032066//nucleolus to nucleoplasm transport;GO:0008285//negative regulation of cell proliferation;GO:0050821//protein stabilization;GO:0007050//cell cycle arrest,GO:0005515//protein binding,K09188//Lysine degradation
84898,0,0,0,0,28,11,40,32,144,0,20,0,PLXDC2;plexin domain containing 2,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome,GO:0007275//multicellular organismal development,GO:0004872//receptor activity;GO:0005515//protein binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer
84899,0,22,0,0,0,11,15,23,46,1,0,0,TMTC4;transmembrane and tetratricopeptide repeat containing 4,GO:0016021//integral component of membrane,-,-,K09667//Other types of O-glycan biosynthesis
8490,34,0,0,0,0,8,13,55,38,0,0,0,RGS5;regulator of G-protein signaling 5,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007165//signal transduction,GO:0005096//GTPase activator activity,K07524//Axon guidance
84900,0,0,0,0,0,0,24,45,0,0,22,0,"RNFT2;ring finger protein, transmembrane 2",GO:0016021//integral component of membrane,-,GO:0008270//zinc ion binding,-
84901,151,0,0,4,0,0,5,0,15,0,0,1,"NFATC2IP;nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001816//cytokine production,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
84902,0,0,0,27,0,40,0,60,9,0,0,0,CEP89;centrosomal protein 89kDa,GO:0005814//centriole;GO:0005829//cytosol;GO:0000922//spindle pole;GO:0097539//ciliary transition fiber;GO:0005758//mitochondrial intermembrane space;GO:0005886//plasma membrane;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0042384//cilium assembly,-,K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC);K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
84904,0,0,0,34,167,11,0,104,0,0,64,0,ARHGEF39;Rho guanine nucleotide exchange factor (GEF) 39,GO:0005886//plasma membrane,GO:0032321//positive regulation of Rho GTPase activity;GO:0030335//positive regulation of cell migration,GO:0005089//Rho guanyl-nucleotide exchange factor activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
84905,1,0,0,0,18,29,0,0,0,0,17,0,ZNF341;zinc finger protein 341,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84908,0,48,0,8,119,0,0,0,21,0,0,0,"FAM136A;family with sequence similarity 136, member A",GO:0005737//cytoplasm;GO:0005739//mitochondrion,-,-,-
84909,73,0,0,13,0,0,80,0,29,1,6,0,C9orf3;chromosome 9 open reading frame 3,GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0019370//leukotriene biosynthetic process;GO:0006508//proteolysis,GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
8491,0,0,0,8,69,17,15,0,35,0,0,185,MAP4K3;mitogen-activated protein kinase kinase kinase kinase 3,-,GO:0050790//regulation of catalytic activity;GO:0007254//JNK cascade;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0009411//response to UV;GO:0034612//response to tumor necrosis factor,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0005524//ATP binding;GO:0005083//small GTPase regulator activity,K04406//MAPK signaling pathway
84910,0,0,0,13,19,0,24,0,28,142,4,0,TMEM87B;transmembrane protein 87B,GO:0016021//integral component of membrane,-,-,-
84911,0,0,0,0,0,0,0,0,5,0,0,0,ZNF382;zinc finger protein 382,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84912,0,0,0,6,22,28,0,0,20,0,0,0,"SLC35B4;solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4",GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0055085//transmembrane transport;GO:0006111//regulation of gluconeogenesis;GO:0008643//carbohydrate transport;GO:0015788//UDP-N-acetylglucosamine transport;GO:0015790//UDP-xylose transport,GO:0005464//UDP-xylose transmembrane transporter activity;GO:0005462//UDP-N-acetylglucosamine transmembrane transporter activity,-
84913,0,0,0,0,0,37,0,0,24,0,10,0,ATOH8;atonal homolog 8 (Drosophila),GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007399//nervous system development;GO:0030154//cell differentiation;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046983//protein dimerization activity,-
84914,5,26,51,7,64,0,0,45,9,0,23,1,ZNF587;zinc finger protein 587,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
84915,88,0,0,0,0,0,0,0,37,0,0,0,"FAM222A;family with sequence similarity 222, member A",-,-,-,-
84916,0,0,0,0,23,0,11,0,3,57,0,0,"CIRH1A;cirrhosis, autosomal recessive 1A (cirhin)",GO:0034455//t-UTP complex;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0030490//maturation of SSU-rRNA;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K14548//Ribosome biogenesis in eukaryotes
84918,98,0,0,26,9,0,25,83,17,0,40,9,LRP11;low density lipoprotein receptor-related protein 11,GO:0016021//integral component of membrane,-,-,K15619//Transcriptional misregulation in cancer
84919,0,40,57,81,11,0,0,88,28,0,26,0,"PPP1R15B;protein phosphatase 1, regulatory subunit 15B",GO:0000164//protein phosphatase type 1 complex,GO:0006983//ER overload response;GO:0042542//response to hydrogen peroxide;GO:0006417//regulation of translation;GO:0016311//dephosphorylation,GO:0005515//protein binding;GO:0004722//protein serine/threonine phosphatase activity,K11447//Transcriptional misregulation in cancer;K00923//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
8492,21,0,0,0,0,0,12,0,51,0,0,0,"PRSS12;protease, serine, 12 (neurotrypsin, motopsin)",GO:0031410//cytoplasmic vesicle;GO:0043195//terminal bouton;GO:0005576//extracellular region;GO:0030424//axon;GO:0043083//synaptic cleft;GO:0005886//plasma membrane;GO:0030425//dendrite,GO:0006887//exocytosis;GO:0006898//receptor-mediated endocytosis;GO:0031638//zymogen activation;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0008236//serine-type peptidase activity;GO:0005044//scavenger receptor activity,-
84920,47,0,0,0,23,16,1,0,0,0,0,0,"ALG10;ALG10, alpha-1,2-glucosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification,"GO:0016758//transferase activity, transferring hexosyl groups",K03850//Metabolic pathways;N-Glycan biosynthesis
84922,0,0,0,0,0,0,0,0,0,56,0,57,FIZ1;FLT3-interacting zinc finger 1,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0001934//positive regulation of protein phosphorylation;GO:0006355//regulation of transcription, DNA-templated",GO:0030971//receptor tyrosine kinase binding;GO:0003676//nucleic acid binding;GO:0019901//protein kinase binding;GO:0046872//metal ion binding,-
84923,0,35,39,60,124,0,0,0,16,0,42,0,"FAM104A;family with sequence similarity 104, member A",-,-,-,-
84924,0,0,0,0,25,0,0,0,0,0,0,0,ZNF566;zinc finger protein 566,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
84925,0,0,0,0,0,2,0,49,48,0,1,0,DIRC2;disrupted in renal carcinoma 2,GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,GO:0006810//transport,-,-
84926,0,2,0,27,83,28,0,0,31,0,0,1,SPRYD3;SPRY domain containing 3,-,-,-,-
84928,0,0,0,0,0,0,0,0,0,0,0,220,TMEM209;transmembrane protein 209,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
84929,0,0,0,0,0,0,3,0,11,0,0,0,FIBCD1;fibrinogen C domain containing 1,GO:0016020//membrane;GO:0016021//integral component of membrane,-,GO:0046872//metal ion binding;GO:0008061//chitin binding,-
8493,0,0,0,1,51,0,36,0,11,0,0,0,"PPM1D;protein phosphatase, Mg2+/Mn2+ dependent, 1D",GO:0005634//nucleus,GO:0009314//response to radiation;GO:0009617//response to bacterium;GO:0035970//peptidyl-threonine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation,GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K10147//p53 signaling pathway
84930,0,9,28,88,100,12,2,0,53,37,104,1,MASTL;microtubule associated serine/threonine kinase-like,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0032154//cleavage furrow,GO:0006974//cellular response to DNA damage stimulus;GO:0034048//negative regulation of protein phosphatase type 2A activity;GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007067//mitotic nuclear division,GO:0051721//protein phosphatase 2A binding;GO:0016301//kinase activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
84931,0,0,0,0,0,16,0,0,7,0,0,0,LINC01101;long intergenic non-protein coding RNA 1101,-,-,-,-
84932,48,0,2,0,65,1,21,0,21,0,0,0,"RAB2B;RAB2B, member RAS oncogene family",GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane,GO:0016192//vesicle-mediated transport;GO:0007264//small GTPase mediated signal transduction;GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport,GO:0005525//GTP binding,-
84933,0,0,0,0,1,0,0,0,8,0,0,0,C8orf76;chromosome 8 open reading frame 76,-,-,-,-
84934,0,0,0,0,9,0,0,0,20,0,0,0,RITA1;RBPJ interacting and tubulin associated 1,GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0045746//negative regulation of Notch signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007219//Notch signaling pathway;GO:0051168//nuclear export;GO:0022008//neurogenesis,GO:0015631//tubulin binding;GO:0005515//protein binding,-
84935,0,0,0,0,0,0,0,58,2,0,0,0,MEDAG;mesenteric estrogen-dependent adipogenesis,GO:0005737//cytoplasm,GO:0045600//positive regulation of fat cell differentiation,-,-
84936,0,0,0,0,10,25,0,0,10,0,0,0,"ZFYVE19;zinc finger, FYVE domain containing 19",GO:0032154//cleavage furrow;GO:0030496//midbody;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0009838//abscission;GO:0032466//negative regulation of cytokinesis;GO:0031565//cytokinesis checkpoint;GO:0051301//cell division,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding,K12182//Endocytosis;Phagosome
84937,0,0,0,7,59,48,48,27,8,0,40,0,"ZNRF1;zinc and ring finger 1, E3 ubiquitin protein ligase",GO:0005764//lysosome;GO:0030672//synaptic vesicle membrane;GO:0005768//endosome;GO:0030054//cell junction;GO:0016020//membrane;GO:0005829//cytosol,GO:0070936//protein K48-linked ubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
84938,0,0,0,0,0,1,32,0,22,0,0,0,"ATG4C;autophagy related 4C, cysteine peptidase",GO:0005829//cytosol;GO:0005576//extracellular region;GO:0005737//cytoplasm,GO:0000045//autophagic vacuole assembly;GO:0006914//autophagy;GO:0006612//protein targeting to membrane;GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0004197//cysteine-type endopeptidase activity,K08342//Regulation of autophagy
84939,0,0,0,12,1,0,54,29,33,0,13,0,MUM1;melanoma associated antigen (mutated) 1,GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0006281//DNA repair,GO:0031491//nucleosome binding;GO:0005515//protein binding,-
84940,232,0,0,0,5,2,12,0,12,0,42,0,CORO6;coronin 6,GO:0015629//actin cytoskeleton,GO:0030036//actin cytoskeleton organization,GO:0051015//actin filament binding,-
84941,92,11,0,0,0,24,0,0,56,0,0,2,HSH2D;hematopoietic SH2 domain containing,GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0009967//positive regulation of signal transduction;GO:0002903//negative regulation of B cell apoptotic process;GO:0042110//T cell activation;GO:0051902//negative regulation of mitochondrial depolarization,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07901//Pancreatic secretion;K08273//VEGF signaling pathway;K11447//Transcriptional misregulation in cancer
84942,0,28,0,6,18,0,0,0,27,141,19,0,WDR73;WD repeat domain 73,-,-,-,-
84944,0,0,62,0,0,0,0,1,10,0,0,0,MAEL;maelstrom spermatogenic transposon silencer,GO:0005737//cytoplasm;GO:0043186//P granule;GO:0071547//piP-body;GO:0030849//autosome;GO:0000785//chromatin;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0001741//XY body;GO:0033391//chromatoid body,GO:0000902//cell morphogenesis;GO:0046620//regulation of organ growth;GO:0007129//synapsis;GO:0043066//negative regulation of apoptotic process;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0009566//fertilization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0031047//gene silencing by RNA;GO:0030154//cell differentiation;GO:0043046//DNA methylation involved in gamete generation;GO:0007140//male meiosis;GO:0034587//piRNA metabolic process,GO:0003677//DNA binding,-
84945,166,0,0,0,15,0,0,0,7,0,0,0,ABHD13;abhydrolase domain containing 13,GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
84946,0,0,0,0,25,0,0,0,1,0,0,0,LTV1;LTV1 ribosome biogenesis factor,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
84947,0,0,0,14,1,0,0,79,2,0,0,0,SERAC1;serine active site containing 1,GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005634//nucleus;GO:0031012//extracellular matrix;GO:0005737//cytoplasm,GO:0030198//extracellular matrix organization;GO:0008654//phospholipid biosynthetic process;GO:0006505//GPI anchor metabolic process;GO:0006886//intracellular protein transport,"GO:0016788//hydrolase activity, acting on ester bonds",K03109//Protein export;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
84948,0,0,0,0,0,0,0,0,6,0,0,0,TIGD5;tigger transposable element derived 5,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
8495,183,28,1,40,49,3,19,50,10,43,0,0,"PPFIBP2;PTPRF interacting protein, binding protein 2 (liprin beta 2)",GO:0048786//presynaptic active zone;GO:0005622//intracellular;GO:0005615//extracellular space,GO:0007160//cell-matrix adhesion;GO:0015074//DNA integration;GO:0007165//signal transduction,GO:0003677//DNA binding;GO:0008907//integrase activity,-
84950,0,74,66,34,40,5,29,0,41,0,1,0,PRPF38A;pre-mRNA processing factor 38A,GO:0005681//spliceosomal complex,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12849//Spliceosome
84951,0,0,0,0,0,42,0,0,52,38,8,0,TNS4;tensin 4,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005925//focal adhesion,GO:0006915//apoptotic process;GO:0008104//protein localization,GO:0005515//protein binding;GO:0003779//actin binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00665//Metabolic pathways;Insulin signaling pathway;Fatty acid biosynthesis;K11447//Transcriptional misregulation in cancer
84952,0,51,33,67,229,28,7,224,68,101,51,0,CGNL1;cingulin-like 1,GO:0005923//tight junction;GO:0016459//myosin complex,GO:0008152//metabolic process,GO:0003774//motor activity,K06102//Tight junction
84953,0,0,0,0,0,28,33,0,0,0,12,0,MICALCL;MICAL C-terminal like,GO:0005737//cytoplasm,GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0051019//mitogen-activated protein kinase binding,-
84955,67,0,0,4,61,37,0,3,11,0,0,0,NUDCD1;NudC domain containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0002376//immune system process,-,-
84957,44,0,0,0,0,27,28,0,13,0,0,0,RELT;RELT tumor necrosis factor receptor,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm,-,-,K05156//Cytokine-cytokine receptor interaction
84958,0,113,26,42,102,0,1,6,39,0,11,0,SYTL1;synaptotagmin-like 1,GO:0019897//extrinsic component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome,GO:0006887//exocytosis;GO:0006886//intracellular protein transport,GO:0042043//neurexin family protein binding;GO:0017137//Rab GTPase binding;GO:0005515//protein binding,K15290//Synaptic vesicle cycle
84959,0,0,0,0,19,0,22,0,36,0,14,0,UBASH3B;ubiquitin associated and SH3 domain containing B,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006469//negative regulation of protein kinase activity;GO:0051279//regulation of release of sequestered calcium ion into cytosol;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0090331//negative regulation of platelet aggregation,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding,-
8496,216,1,0,22,38,23,0,0,42,0,12,0,"PPFIBP1;PTPRF interacting protein, binding protein 1 (liprin beta 1)",GO:0048786//presynaptic active zone;GO:0005925//focal adhesion;GO:0005886//plasma membrane,GO:0007155//cell adhesion;GO:0007165//signal transduction;GO:0007160//cell-matrix adhesion,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
84960,0,66,91,32,22,0,0,145,88,0,132,0,CCDC183;coiled-coil domain containing 183,-,-,-,K09291//Pathways in cancer;MAPK signaling pathway - yeast;Thyroid cancer;RNA transport
84961,0,0,1,12,60,14,45,0,86,1,30,0,FBXL20;F-box and leucine-rich repeat protein 20,GO:0005737//cytoplasm,GO:0001662//behavioral fear response,-,-
84962,0,0,0,0,0,18,21,0,35,0,0,0,AJUBA;ajuba LIM protein,GO:0005911//cell-cell junction;GO:0000932//cytoplasmic mRNA processing body;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0005815//microtubule organizing center;GO:0005667//transcription factor complex;GO:0005925//focal adhesion;GO:0005829//cytosol,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0030032//lamellipodium assembly;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0034613//cellular protein localization;GO:0031328//positive regulation of cellular biosynthetic process;GO:0001666//response to hypoxia;GO:0035313//wound healing, spreading of epidermal cells;GO:0030334//regulation of cell migration;GO:0033673//negative regulation of kinase activity;GO:0048041//focal adhesion assembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043087//regulation of GTPase activity;GO:0006351//transcription, DNA-templated;GO:2000637//positive regulation of gene silencing by miRNA;GO:0031334//positive regulation of protein complex assembly;GO:0035331//negative regulation of hippo signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043406//positive regulation of MAP kinase activity;GO:0035195//gene silencing by miRNA;GO:0046474//glycerophospholipid biosynthetic process;GO:1900037//regulation of cellular response to hypoxia",GO:0045294//alpha-catenin binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0051015//actin filament binding,K12792//NOD-like receptor signaling pathway
84966,0,0,0,0,4,0,0,0,2,0,0,0,"IGSF21;immunoglobin superfamily, member 21",GO:0005576//extracellular region,-,-,K06255//ECM-receptor interaction
84967,0,0,0,3,3,0,0,0,12,0,0,0,"LSM10;LSM10, U7 small nuclear RNA associated",GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005683//U7 snRNP,GO:0006369//termination of RNA polymerase II transcription;GO:0010467//gene expression;GO:0008380//RNA splicing;GO:0008334//histone mRNA metabolic process;GO:0031124//mRNA 3'-end processing;GO:0006366//transcription from RNA polymerase II promoter;GO:1900087//positive regulation of G1/S transition of mitotic cell cycle,GO:0071208//histone pre-mRNA DCP binding;GO:0005515//protein binding,K11087//Systemic lupus erythematosus;Spliceosome;K12621//Spliceosome;RNA degradation
84969,0,0,0,0,0,7,26,0,0,205,0,0,TOX2;TOX high mobility group box family member 2,GO:0005634//nucleus,"GO:0008585//female gonad development;GO:0034698//response to gonadotropin;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001085//RNA polymerase II transcription factor binding;GO:0003677//DNA binding,-
84970,0,0,0,0,0,6,0,0,1,0,0,0,C1orf94;chromosome 1 open reading frame 94,-,-,GO:0005515//protein binding,-
84971,0,0,0,10,25,7,0,0,53,0,0,0,"ATG4D;autophagy related 4D, cysteine peptidase",GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0006508//proteolysis;GO:0006914//autophagy;GO:0006915//apoptotic process,GO:0004197//cysteine-type endopeptidase activity,K08342//Regulation of autophagy
84975,0,28,0,0,0,4,0,0,37,0,0,0,MFSD5;major facilitator superfamily domain containing 5,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport,-,-
84976,0,0,0,0,0,0,63,0,50,171,0,0,DISP1;dispatched homolog 1 (Drosophila),GO:0016021//integral component of membrane,GO:0009880//embryonic pattern specification;GO:0060539//diaphragm development;GO:0007368//determination of left/right symmetry;GO:0007225//patched ligand maturation;GO:0007224//smoothened signaling pathway;GO:0015833//peptide transport;GO:0009953//dorsal/ventral pattern formation,GO:0015197//peptide transporter activity;GO:0008158//hedgehog receptor activity,K12385//Lysosome
84978,3,0,22,28,16,20,0,177,38,1,38,5,FRMD5;FERM domain containing 5,GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton,-,GO:0008092//cytoskeletal protein binding;GO:0005515//protein binding,K06107//Tight junction
84984,0,20,0,5,0,0,0,0,15,36,0,0,CEP19;centrosomal protein 19kDa,GO:0000922//spindle pole;GO:0005814//centriole;GO:0036064//ciliary basal body,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Oxidative phosphorylation;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption
84985,0,0,0,0,0,0,96,0,58,9,0,0,"FAM83A;family with sequence similarity 83, member A",-,-,-,K11447//Transcriptional misregulation in cancer
84986,19,0,0,2,17,0,14,28,0,0,0,0,ARHGAP19;Rho GTPase activating protein 19,GO:0005634//nucleus;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K08878//Chronic myeloid leukemia;Pathways in cancer;K12490//Endocytosis
84987,0,0,1,0,14,15,0,0,3,0,13,0,COX14;cytochrome c oxidase assembly homolog 14 (S. cerevisiae),GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005739//mitochondrion,GO:0033617//mitochondrial respiratory chain complex IV assembly,-,-
84988,0,1,1,14,43,0,0,2,10,6,11,0,"PPP1R16A;protein phosphatase 1, regulatory subunit 16A",GO:0005886//plasma membrane,-,GO:0005515//protein binding,K06270//Focal adhesion;Long-term potentiation;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;K12329//Vascular smooth muscle contraction
84989,0,0,0,11,33,0,15,0,15,45,35,0,JMJD1C-AS1;JMJD1C antisense RNA 1,-,-,-,K11449//Transcriptional misregulation in cancer
8499,5,24,0,0,18,39,0,0,52,0,0,590,"PPFIA2;protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2",GO:0005737//cytoplasm;GO:0048786//presynaptic active zone;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface,GO:0007160//cell-matrix adhesion;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0032403//protein complex binding,K10352//Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
84991,0,0,0,0,37,0,1,0,12,0,0,0,RBM17;RNA binding motif protein 17,GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0000380//alternative mRNA splicing, via spliceosome",GO:0003723//RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K12840//Spliceosome
84993,0,0,1,0,13,23,32,0,36,0,0,0,UBL7;ubiquitin-like 7,-,-,-,-
8500,89,1,27,0,106,46,7,0,47,0,18,0,"PPFIA1;protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1",GO:0005737//cytoplasm;GO:0048786//presynaptic active zone;GO:0005925//focal adhesion,GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0007165//signal transduction;GO:0007160//cell-matrix adhesion;GO:0051497//negative regulation of stress fiber assembly,GO:0005515//protein binding;GO:0004871//signal transducer activity,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K02936//Ribosome
85002,0,0,0,0,0,0,0,126,0,0,64,0,"FAM86B1;family with sequence similarity 86, member B1",-,-,-,K03842//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
85004,0,1,0,13,18,25,0,0,26,0,0,0,"RERG;RAS-like, estrogen-regulated, growth inhibitor",GO:0016020//membrane;GO:0005829//cytosol;GO:0005634//nucleus,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process;GO:0009725//response to hormone;GO:0008285//negative regulation of cell proliferation;GO:0030308//negative regulation of cell growth,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0019003//GDP binding;GO:0030331//estrogen receptor binding,-
85007,0,14,0,0,1,14,39,0,26,0,0,0,PHYKPL;5-phosphohydroxy-L-lysine phospho-lyase,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0008483//transaminase activity;GO:0030170//pyridoxal phosphate binding;GO:0016829//lyase activity,-
8501,0,0,0,0,0,11,0,119,83,0,0,0,"SLC43A1;solute carrier family 43 (amino acid system L transporter), member 1",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:1902475//L-alpha-amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0015804//neutral amino acid transport,GO:0015175//neutral amino acid transmembrane transporter activity;GO:0015179//L-amino acid transmembrane transporter activity,-
85012,0,0,0,0,44,20,0,45,6,0,0,0,TCEAL3;transcription elongation factor A (SII)-like 3,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
85013,0,0,0,0,0,15,1,0,33,0,0,0,TMEM128;transmembrane protein 128,GO:0016021//integral component of membrane,-,-,-
85014,0,2,0,3,21,0,0,0,8,0,0,0,TMEM141;transmembrane protein 141,GO:0016021//integral component of membrane,-,-,-
85015,0,41,0,16,35,0,13,0,110,0,5,0,USP45;ubiquitin specific peptidase 45,-,GO:0016579//protein deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0008270//zinc ion binding;GO:0004843//ubiquitin-specific protease activity,-
85016,0,0,0,0,6,7,20,0,0,0,0,0,C11orf70;chromosome 11 open reading frame 70,-,-,-,K14443//RNA degradation;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;Metabolic pathways;beta-Alanine metabolism;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
85019,0,0,0,0,0,15,0,0,29,14,0,0,TMEM241;transmembrane protein 241,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
8502,0,16,0,40,255,0,13,0,0,0,0,0,PKP4;plakophilin 4,GO:0048471//perinuclear region of cytoplasm;GO:0000922//spindle pole;GO:0030057//desmosome;GO:0030496//midbody;GO:0044291//cell-cell contact zone;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005856//cytoskeleton;GO:0005886//plasma membrane;GO:0072686//mitotic spindle;GO:0009898//cytoplasmic side of plasma membrane;GO:0051233//spindle midzone,GO:0007267//cell-cell signaling;GO:0032321//positive regulation of Rho GTPase activity;GO:0032467//positive regulation of cytokinesis;GO:0030155//regulation of cell adhesion;GO:0007043//cell-cell junction assembly;GO:0016337//single organismal cell-cell adhesion;GO:0010628//positive regulation of gene expression,GO:0005515//protein binding,K05690//Leukocyte transendothelial migration;Adherens junction
85021,0,43,0,0,48,37,0,2,36,1,6,0,REPS1;RALBP1 associated Eps domain containing 1,GO:0005905//coated pit;GO:0005886//plasma membrane,GO:0006898//receptor-mediated endocytosis,GO:0017124//SH3 domain binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K12476//Endocytosis;K12483//Endocytosis
85026,0,0,98,11,8,7,0,0,14,0,50,0,C9orf37;chromosome 9 open reading frame 37,-,-,-,K06641//Cell cycle;Cell cycle - yeast;p53 signaling pathway;HTLV-I infection
85027,0,0,0,0,0,27,0,0,28,0,0,0,SMIM3;small integral membrane protein 3,GO:0016021//integral component of membrane,-,-,-
8503,0,0,0,26,54,29,22,7,7,0,18,0,"PIK3R3;phosphoinositide-3-kinase, regulatory subunit 3 (gamma)",GO:0005829//cytosol;GO:0005942//phosphatidylinositol 3-kinase complex,GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0006644//phospholipid metabolic process;GO:0043551//regulation of phosphatidylinositol 3-kinase activity,GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0016303//1-phosphatidylinositol-3-kinase activity;GO:0005515//protein binding,K02649//Measles;Regulation of actin cytoskeleton;Melanoma;Neurotrophin signaling pathway;Hepatitis C;Non-small cell lung cancer;B cell receptor signaling pathway;Acute myeloid leukemia;Cholinergic synapse;Fc epsilon RI signaling pathway;Chagas disease (American trypanosomiasis);Colorectal cancer;Amoebiasis;Type II diabetes mellitus;Chronic myeloid leukemia;T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Small cell lung cancer;Progesterone-mediated oocyte maturation;Carbohydrate digestion and absorption;Prostate cancer;Aldosterone-regulated sodium reabsorption;Insulin signaling pathway;Phosphatidylinositol signaling system;VEGF signaling pathway;Focal adhesion;Glioma;Osteoclast differentiation;Toxoplasmosis;Endometrial cancer;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis;Jak-STAT signaling pathway;HTLV-I infection;Bacterial invasion of epithelial cells;Epstein-Barr virus infection;Renal cell carcinoma;ErbB signaling pathway;mTOR signaling pathway;Apoptosis;Influenza A;Toll-like receptor signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer
8504,0,0,0,12,0,15,0,0,49,0,0,0,PEX3;peroxisomal biogenesis factor 3,GO:0005779//integral component of peroxisomal membrane;GO:0005730//nucleolus;GO:0032994//protein-lipid complex;GO:0005829//cytosol;GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005777//peroxisome;GO:0043234//protein complex,GO:0016557//peroxisome membrane biogenesis;GO:0007031//peroxisome organization;GO:0055085//transmembrane transport;GO:0045046//protein import into peroxisome membrane,GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0008289//lipid binding,K13336//Peroxisome
8505,0,0,0,4,30,0,0,0,16,0,0,0,PARG;poly (ADP-ribose) glycohydrolase,GO:0005634//nucleus;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0005975//carbohydrate metabolic process,GO:0004649//poly(ADP-ribose) glycohydrolase activity,-
8506,0,1,0,0,0,25,45,0,29,0,0,0,CNTNAP1;contactin associated protein 1,GO:0005887//integral component of plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0033270//paranode region of axon;GO:0016021//integral component of membrane,GO:0030913//paranodal junction assembly;GO:0009967//positive regulation of signal transduction;GO:0048812//neuron projection morphogenesis;GO:0050884//neuromuscular process controlling posture;GO:0007165//signal transduction;GO:0050885//neuromuscular process controlling balance;GO:0002175//protein localization to paranode region of axon;GO:0007155//cell adhesion;GO:0019227//neuronal action potential propagation;GO:0008088//axon cargo transport;GO:0007010//cytoskeleton organization;GO:0007411//axon guidance,GO:0004872//receptor activity;GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding;GO:0017124//SH3 domain binding,K07379//Cell adhesion molecules (CAMs)
8507,105,0,0,0,0,0,0,0,1,0,0,0,ENC1;ectodermal-neural cortex 1 (with BTB domain),GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0016363//nuclear matrix;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0007275//multicellular organismal development;GO:0007399//nervous system development;GO:0016567//protein ubiquitination;GO:0017148//negative regulation of translation;GO:0010499//proteasomal ubiquitin-independent protein catabolic process,GO:0005515//protein binding;GO:0003779//actin binding,K12373//Lysosome;Glycosphingolipid biosynthesis - globo series;Other glycan degradation;Glycosaminoglycan degradation;Glycosphingolipid biosynthesis - ganglio series;ABC transporters;Metabolic pathways;Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;RNA degradation
8508,0,73,1,14,95,0,9,0,12,0,2,0,NIPSNAP1;nipsnap homolog 1 (C. elegans),GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0097060//synaptic membrane,GO:0019233//sensory perception of pain,GO:0042165//neurotransmitter binding,-
8509,16,0,31,0,0,0,0,0,2,7,0,0,NDST2;N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0030210//heparin biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,GO:0016787//hydrolase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity,K02577//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
8510,34,0,0,0,0,0,0,0,0,0,0,0,MMP23B;matrix metallopeptidase 23B,GO:0005789//endoplasmic reticulum membrane;GO:0005578//proteinaceous extracellular matrix;GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0006508//proteolysis;GO:0000003//reproduction,GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
8511,0,0,0,0,0,3,0,51,0,0,1,0,MMP23A;matrix metallopeptidase 23A (pseudogene),-,-,-,-
8512,0,0,0,0,0,0,0,0,0,0,7,0,"MBL1P;mannose-binding lectin (protein A) 1, pseudogene",-,-,-,K03991//Phagosome;Staphylococcus aureus infection;Complement and coagulation cascades
8513,0,0,0,0,0,0,0,0,25,0,16,0,"LIPF;lipase, gastric",GO:0005576//extracellular region;GO:0005739//mitochondrion,GO:0006641//triglyceride metabolic process;GO:0006108//malate metabolic process;GO:0016042//lipid catabolic process;GO:0055114//oxidation-reduction process,GO:0008289//lipid binding;GO:0016615//malate dehydrogenase activity;GO:0004806//triglyceride lipase activity,K14452//Metabolic pathways;Fat digestion and absorption;Glycerolipid metabolism
8514,0,28,0,7,1,11,13,126,37,113,31,0,"KCNAB2;potassium voltage-gated channel, shaker-related subfamily, beta member 2",GO:0016021//integral component of membrane;GO:0044224//juxtaparanode region of axon;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0051291//protein heterooligomerization;GO:0071805//potassium ion transmembrane transport;GO:0002244//hematopoietic progenitor cell differentiation;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005249//voltage-gated potassium channel activity;GO:0015459//potassium channel regulator activity,-
8515,0,0,0,0,0,15,0,102,40,5,4,0,"ITGA10;integrin, alpha 10",GO:0008305//integrin complex;GO:0005886//plasma membrane,GO:0007229//integrin-mediated signaling pathway;GO:0007411//axon guidance;GO:0007160//cell-matrix adhesion;GO:0030198//extracellular matrix organization;GO:0007596//blood coagulation,GO:0005518//collagen binding;GO:0046872//metal ion binding,K06586//Focal adhesion;Dilated cardiomyopathy;Regulation of actin cytoskeleton;ECM-receptor interaction;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC)
8516,9,0,0,0,0,7,24,34,60,0,12,1,"ITGA8;integrin, alpha 8",GO:0005886//plasma membrane;GO:0005783//endoplasmic reticulum;GO:0032591//dendritic spine membrane;GO:0009986//cell surface;GO:0008305//integrin complex;GO:0045177//apical part of cell;GO:0014069//postsynaptic density;GO:0005925//focal adhesion;GO:0043204//perikaryon;GO:0034678//integrin alpha8-beta1 complex,GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0007160//cell-matrix adhesion;GO:0045184//establishment of protein localization;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0007613//memory;GO:0030030//cell projection organization;GO:0007229//integrin-mediated signaling pathway;GO:0034446//substrate adhesion-dependent cell spreading;GO:0016337//single organismal cell-cell adhesion;GO:0007420//brain development;GO:0048745//smooth muscle tissue development;GO:0048333//mesodermal cell differentiation;GO:0001656//metanephros development;GO:0001822//kidney development;GO:0030198//extracellular matrix organization;GO:0042472//inner ear morphogenesis,GO:0046872//metal ion binding,K06584//Dilated cardiomyopathy;Focal adhesion;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Cell adhesion molecules (CAMs);ECM-receptor interaction;Regulation of actin cytoskeleton
8517,0,25,1,21,0,1,0,0,30,4,12,0,"IKBKG;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma",GO:0005829//cytosol;GO:0005622//intracellular;GO:0008385//IkappaB kinase complex;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0034134//toll-like receptor 2 signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0000187//activation of MAPK activity;GO:0002224//toll-like receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0006974//cellular response to DNA damage stimulus;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0001782//B cell homeostasis;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0006915//apoptotic process;GO:0034138//toll-like receptor 3 signaling pathway;GO:0007254//JNK cascade;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0009615//response to virus;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0006351//transcription, DNA-templated;GO:0006955//immune response;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0016032//viral process;GO:0050852//T cell receptor signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway",GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0031625//ubiquitin protein ligase binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0019904//protein domain specific binding,K07210//Toxoplasmosis;Osteoclast differentiation;Adipocytokine signaling pathway;Hepatitis C;Cytosolic DNA-sensing pathway;NOD-like receptor signaling pathway;B cell receptor signaling pathway;Shigellosis;Chagas disease (American trypanosomiasis);Acute myeloid leukemia;HTLV-I infection;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;RIG-I-like receptor signaling pathway;Apoptosis;T cell receptor signaling pathway;Herpes simplex infection;MAPK signaling pathway;Chronic myeloid leukemia;Prostate cancer;Small cell lung cancer;Toll-like receptor signaling pathway;Pathways in cancer;Chemokine signaling pathway;Primary immunodeficiency;Pancreatic cancer;NF-kappa B signaling pathway
8518,15,7,0,40,40,6,21,1,50,8,20,372,"IKBKAP;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein","GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0033588//Elongator holoenzyme complex;GO:0008023//transcription elongation factor complex",GO:0030335//positive regulation of cell migration;GO:0006468//protein phosphorylation;GO:0006325//chromatin organization;GO:0006955//immune response;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0045859//regulation of protein kinase activity;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006461//protein complex assembly,GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0008607//phosphorylase kinase regulator activity,-
8519,0,0,0,0,10,0,0,0,11,0,0,0,IFITM1;interferon induced transmembrane protein 1,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway;GO:0050776//regulation of immune response;GO:0034341//response to interferon-gamma;GO:0019221//cytokine-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0035455//response to interferon-alpha;GO:0045669//positive regulation of osteoblast differentiation;GO:0001503//ossification;GO:0046597//negative regulation of viral entry into host cell;GO:0035556//intracellular signal transduction;GO:0030336//negative regulation of cell migration;GO:0009615//response to virus;GO:0035456//response to interferon-beta;GO:0008285//negative regulation of cell proliferation,GO:0005515//protein binding;GO:0005057//receptor signaling protein activity,K06566//B cell receptor signaling pathway
8520,0,0,0,23,63,10,0,0,20,15,0,0,HAT1;histone acetyltransferase 1,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0016363//nuclear matrix;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0006348//chromatin silencing at telomere;GO:0006335//DNA replication-dependent nucleosome assembly;GO:0006475//internal protein amino acid acetylation;GO:0043967//histone H4 acetylation;GO:0006323//DNA packaging;GO:0006325//chromatin organization;GO:0006336//DNA replication-independent nucleosome assembly;GO:0007584//response to nutrient,GO:0004402//histone acetyltransferase activity;GO:0010485//H4 histone acetyltransferase activity;GO:0005515//protein binding,K11303//Alcoholism
8521,0,0,0,0,0,0,5,0,25,0,0,0,GCM1;glial cells missing homolog 1 (Drosophila),GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0060018//astrocyte fate commitment;GO:0060143//positive regulation of syncytium formation by plasma membrane fusion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060706//cell differentiation involved in embryonic placenta development;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0008134//transcription factor binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion
8522,1,0,0,0,0,0,0,0,90,1,1,0,GAS7;growth arrest-specific 7,GO:0001726//ruffle;GO:0005737//cytoplasm;GO:0005884//actin filament,"GO:0030041//actin filament polymerization;GO:0007050//cell cycle arrest;GO:0051017//actin filament bundle assembly;GO:0048812//neuron projection morphogenesis;GO:0008360//regulation of cell shape;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0051015//actin filament binding,K11447//Transcriptional misregulation in cancer;K12804//NOD-like receptor signaling pathway;K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
85235,0,0,0,0,0,0,0,0,0,74,0,0,"HIST1H2AH;histone cluster 1, H2ah",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Systemic lupus erythematosus;Alcoholism
85236,0,10,0,19,42,0,30,0,0,0,0,0,"HIST1H2BK;histone cluster 1, H2bk",GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium;GO:0002227//innate immune response in mucosa;GO:0006325//chromatin organization,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity,K11252//Alcoholism;Systemic lupus erythematosus
8525,76,31,0,0,1,0,36,0,71,0,19,0,"DGKZ;diacylglycerol kinase, zeta",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0030027//lamellipodium;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0045930//negative regulation of mitotic cell cycle;GO:0016477//cell migration;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0030168//platelet activation;GO:0046580//negative regulation of Ras protein signal transduction;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0007596//blood coagulation;GO:0046834//lipid phosphorylation;GO:0043086//negative regulation of catalytic activity;GO:0035556//intracellular signal transduction,GO:0001727//lipid kinase activity;GO:0003951//NAD+ kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004143//diacylglycerol kinase activity;GO:0004857//enzyme inhibitor activity;GO:0008022//protein C-terminus binding,K00901//Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways;Glycerophospholipid metabolism
8526,0,0,0,0,0,0,6,0,46,0,0,0,"DGKE;diacylglycerol kinase, epsilon 64kDa",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0007596//blood coagulation;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0016310//phosphorylation;GO:0035556//intracellular signal transduction;GO:0008654//phospholipid biosynthetic process;GO:0030168//platelet activation,GO:0003951//NAD+ kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0046872//metal ion binding;GO:0005524//ATP binding,K00901//Glycerophospholipid metabolism;Metabolic pathways;Glycerolipid metabolism;Phosphatidylinositol signaling system
8527,0,38,0,19,77,41,26,42,125,0,13,0,"DGKD;diacylglycerol kinase, delta 130kDa",GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005737//cytoplasm,GO:0007275//multicellular organismal development;GO:0015031//protein transport;GO:0007596//blood coagulation;GO:0006897//endocytosis;GO:0019932//second-messenger-mediated signaling;GO:0030168//platelet activation;GO:0007165//signal transduction;GO:0046339//diacylglycerol metabolic process;GO:0016049//cell growth;GO:0016310//phosphorylation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0010033//response to organic substance;GO:0051260//protein homooligomerization;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0005524//ATP binding;GO:0003951//NAD+ kinase activity;GO:0019992//diacylglycerol binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0004143//diacylglycerol kinase activity,K00901//Glycerolipid metabolism;Phosphatidylinositol signaling system;Metabolic pathways;Glycerophospholipid metabolism
8528,13,0,0,0,0,0,0,0,14,0,0,0,DDO;D-aspartate oxidase,GO:0005777//peroxisome,GO:0055114//oxidation-reduction process;GO:0042445//hormone metabolic process;GO:0006533//aspartate catabolic process;GO:0007625//grooming behavior;GO:0006531//aspartate metabolic process;GO:0007320//insemination;GO:0019478//D-amino acid catabolic process,GO:0048037//cofactor binding;GO:0008445//D-aspartate oxidase activity;GO:0005515//protein binding;GO:0005102//receptor binding,"K00272//Peroxisome;Alanine, aspartate and glutamate metabolism"
85280,0,0,0,0,0,0,0,0,0,0,0,3,KRTAP9-4;keratin associated protein 9-4,GO:0045095//keratin filament,-,-,-
85289,0,0,0,0,0,0,0,0,3,0,0,0,KRTAP4-5;keratin associated protein 4-5,GO:0045095//keratin filament,GO:0007568//aging;GO:0042633//hair cycle,-,-
8529,149,0,0,0,0,0,0,0,11,0,0,0,"CYP4F2;cytochrome P450, family 4, subfamily F, polypeptide 2",GO:0043231//intracellular membrane-bounded organelle;GO:0005789//endoplasmic reticulum membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0032305//positive regulation of icosanoid secretion;GO:0055078//sodium ion homeostasis;GO:0042371//vitamin K biosynthetic process;GO:0019373//epoxygenase P450 pathway;GO:0019369//arachidonic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0007596//blood coagulation;GO:0017144//drug metabolic process;GO:0008217//regulation of blood pressure;GO:0003091//renal water homeostasis;GO:0030195//negative regulation of blood coagulation;GO:0097267//omega-hydroxylase P450 pathway;GO:0000038//very long-chain fatty acid metabolic process;GO:0042360//vitamin E metabolic process;GO:0006691//leukotriene metabolic process;GO:0036101//leukotriene B4 catabolic process;GO:0006805//xenobiotic metabolic process;GO:0001676//long-chain fatty acid metabolic process;GO:0044281//small molecule metabolic process;GO:0042376//phylloquinone catabolic process;GO:0003095//pressure natriuresis;GO:0032304//negative regulation of icosanoid secretion,"GO:0005515//protein binding;GO:0052871//alpha-tocopherol omega-hydroxylase activity;GO:0008392//arachidonic acid epoxygenase activity;GO:0047057//vitamin-K-epoxide reductase (warfarin-sensitive) activity;GO:0052869//arachidonic acid omega-hydroxylase activity;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen;GO:0005506//iron ion binding;GO:0018685//alkane 1-monooxygenase activity;GO:0052872//tocotrienol omega-hydroxylase activity;GO:0050051//leukotriene-B4 20-monooxygenase activity;GO:0020037//heme binding",K00490//Arachidonic acid metabolism;Metabolic pathways
85290,0,0,0,0,0,0,0,48,0,0,0,0,KRTAP4-3;keratin associated protein 4-3,GO:0045095//keratin filament,GO:0042633//hair cycle;GO:0007568//aging,-,-
85294,0,0,0,0,0,0,0,0,6,0,0,0,KRTAP2-4;keratin associated protein 2-4,GO:0045095//keratin filament,-,-,-
8530,0,0,0,0,0,0,0,0,9,0,33,0,CST7;cystatin F (leukocystatin),GO:0005737//cytoplasm;GO:0005576//extracellular region,GO:0006955//immune response;GO:0010951//negative regulation of endopeptidase activity,GO:0004866//endopeptidase inhibitor activity;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0005515//protein binding,-
85300,0,0,0,0,0,0,0,0,64,0,12,0,"ATCAY;ataxia, cerebellar, Cayman type",GO:0030424//axon;GO:0005739//mitochondrion;GO:0031966//mitochondrial membrane;GO:0030425//dendrite;GO:0045202//synapse;GO:0030054//cell junction;GO:0043005//neuron projection;GO:0005737//cytoplasm,GO:0006810//transport;GO:0032880//regulation of protein localization;GO:2000212//negative regulation of glutamate metabolic process;GO:0006915//apoptotic process;GO:0048311//mitochondrion distribution;GO:0031175//neuron projection development,GO:0019894//kinesin binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01514//Purine metabolism
85301,67,0,0,0,2,15,57,24,49,97,29,0,"COL27A1;collagen, type XXVII, alpha 1",GO:0005788//endoplasmic reticulum lumen;GO:0005576//extracellular region;GO:0005583//fibrillar collagen trimer,GO:0030198//extracellular matrix organization,GO:0005201//extracellular matrix structural constituent;GO:0046872//metal ion binding,K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
85302,0,0,0,0,12,0,0,43,27,0,20,0,FBF1;Fas (TNFRSF6) binding factor 1,GO:0097539//ciliary transition fiber;GO:0005814//centriole;GO:0045095//keratin filament;GO:0000922//spindle pole;GO:0043296//apical junction complex,GO:0090162//establishment of epithelial cell polarity;GO:0043297//apical junction assembly;GO:0042384//cilium assembly,GO:0005515//protein binding,-
8531,0,0,1,22,43,0,0,0,19,0,7,0,YBX3;Y box binding protein 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005844//polysome;GO:0005923//tight junction,"GO:0001701//in utero embryonic development;GO:0006351//transcription, DNA-templated;GO:0009409//response to cold;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0043066//negative regulation of apoptotic process;GO:2000767//positive regulation of cytoplasmic translation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0046622//positive regulation of organ growth;GO:0060546//negative regulation of necroptotic process;GO:0071474//cellular hyperosmotic response;GO:0071356//cellular response to tumor necrosis factor;GO:0048642//negative regulation of skeletal muscle tissue development;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0008584//male gonad development;GO:0007283//spermatogenesis;GO:0009566//fertilization",GO:0017048//Rho GTPase binding;GO:0003697//single-stranded DNA binding;GO:0003714//transcription corepressor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003730//mRNA 3'-UTR binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0003690//double-stranded DNA binding,K06099//Tight junction
85313,75,1,0,15,27,14,0,0,0,0,0,0,PPIL4;peptidylprolyl isomerase (cyclophilin)-like 4,GO:0005634//nucleus,GO:0000413//protein peptidyl-prolyl isomerization;GO:0006457//protein folding,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
85315,27,0,0,0,0,9,6,60,0,0,0,0,PAQR8;progestin and adipoQ receptor family member VIII,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0048545//response to steroid hormone;GO:0007275//multicellular organismal development;GO:0048477//oogenesis;GO:0043401//steroid hormone mediated signaling pathway,GO:0003707//steroid hormone receptor activity;GO:0005496//steroid binding,K07297//Adipocytokine signaling pathway
85317,2,0,0,0,0,0,0,0,0,0,0,0,"BAGE4;B melanoma antigen family, member 4",GO:0005576//extracellular region,-,-,K09188//Lysine degradation
8532,0,0,0,0,0,0,5,0,0,0,0,0,CPZ;carboxypeptidase Z,GO:0005578//proteinaceous extracellular matrix;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0016055//Wnt signaling pathway,GO:0004181//metallocarboxypeptidase activity;GO:0008270//zinc ion binding,-
85320,109,0,0,9,0,12,91,0,28,92,25,0,"ABCC11;ATP-binding cassette, sub-family C (CFTR/MRP), member 11",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:0006200//ATP catabolic process;GO:0015711//organic anion transport;GO:0015865//purine nucleotide transport,"GO:0005524//ATP binding;GO:0015216//purine nucleotide transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05671//ABC transporters
85329,0,0,0,0,0,12,0,0,10,0,7,0,"LGALS12;lectin, galactoside-binding, soluble, 12",GO:0005634//nucleus,GO:0097193//intrinsic apoptotic signaling pathway,GO:0030395//lactose binding,-
8533,0,0,0,30,56,0,49,0,14,0,0,0,COPS3;COP9 signalosome subunit 3,GO:0005737//cytoplasm;GO:0008180//COP9 signalosome,GO:0007165//signal transduction;GO:0009416//response to light stimulus;GO:0010388//cullin deneddylation;GO:0001701//in utero embryonic development,GO:0005515//protein binding,-
8534,0,0,0,0,0,1,0,0,39,0,0,0,CHST1;carbohydrate (keratan sulfate Gal-6) sulfotransferase 1,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0006012//galactose metabolic process;GO:0005976//polysaccharide metabolic process,GO:0008146//sulfotransferase activity;GO:0045130//keratan sulfotransferase activity,K01022//Glycosaminoglycan biosynthesis - keratan sulfate
8535,0,6,0,7,9,4,0,0,0,0,0,0,CBX4;chromobox homolog 4,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0031519//PcG protein complex;GO:0035102//PRC1 complex;GO:0016607//nuclear speck,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0016925//protein sumoylation;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016568//chromatin modification;GO:0043066//negative regulation of apoptotic process",GO:0016874//ligase activity;GO:0035064//methylated histone binding;GO:0003727//single-stranded RNA binding;GO:0019899//enzyme binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0044212//transcription regulatory region DNA binding;GO:0032183//SUMO binding,-
85352,48,0,0,0,0,54,32,46,70,0,4,0,KIAA1644;KIAA1644,GO:0016021//integral component of membrane,-,-,-
85358,19,1,0,1,14,50,52,0,44,180,2,0,SHANK3;SH3 and multiple ankyrin repeat domains 3,GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0097481//neuronal postsynaptic density;GO:0043005//neuron projection;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0005737//cytoplasm;GO:0060170//ciliary membrane;GO:0044309//neuron spine,"GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0021773//striatal medium spiny neuron differentiation;GO:0051835//positive regulation of synapse structural plasticity;GO:0035176//social behavior;GO:0097114//N-methyl-D-aspartate receptor clustering;GO:0030534//adult behavior;GO:2000969//positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0097113//alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering;GO:1900271//regulation of long-term synaptic potentiation;GO:0032232//negative regulation of actin filament bundle assembly;GO:0007613//memory;GO:0007416//synapse assembly;GO:0045794//negative regulation of cell volume;GO:0097107//postsynaptic density assembly;GO:0060997//dendritic spine morphogenesis;GO:0007612//learning;GO:1900451//positive regulation of glutamate receptor signaling pathway;GO:1900452//regulation of long term synaptic depression;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0061001//regulation of dendritic spine morphogenesis;GO:0097117//guanylate kinase-associated protein clustering;GO:0048854//brain morphogenesis;GO:0000165//MAPK cascade;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0042297//vocal learning;GO:0071625//vocalization behavior;GO:0060999//positive regulation of dendritic spine development",GO:0003779//actin binding;GO:0042802//identical protein binding;GO:0030160//GKAP/Homer scaffold activity;GO:0017124//SH3 domain binding;GO:0097110//scaffold protein binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0035255//ionotropic glutamate receptor binding,K15009//Glutamatergic synapse
85359,0,0,0,4,0,18,2,1,0,0,0,0,DGCR6L;DiGeorge syndrome critical region gene 6-like,GO:0005634//nucleus,-,-,-
8536,0,13,24,55,101,0,1,60,20,0,59,254,CAMK1;calcium/calmodulin-dependent protein kinase I,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0010976//positive regulation of neuron projection development;GO:0007165//signal transduction;GO:0007049//cell cycle;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0043393//regulation of protein binding;GO:0051149//positive regulation of muscle cell differentiation;GO:0032880//regulation of protein localization;GO:0006913//nucleocytoplasmic transport;GO:0046827//positive regulation of protein export from nucleus;GO:0060999//positive regulation of dendritic spine development;GO:0006468//protein phosphorylation;GO:0051147//regulation of muscle cell differentiation;GO:0051835//positive regulation of synapse structural plasticity,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding,-
85360,0,0,0,0,0,0,0,0,9,0,0,0,"SYDE1;synapse defective 1, Rho GTPase, homolog 1 (C. elegans)",GO:0044300//cerebellar mossy fiber;GO:0097060//synaptic membrane;GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0050806//positive regulation of synaptic transmission;GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0032862//activation of Rho GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0007130//synaptonemal complex assembly,GO:0005100//Rho GTPase activator activity;GO:0032403//protein complex binding,K08878//Pathways in cancer;Chronic myeloid leukemia;K04450//Amphetamine addiction;MAPK signaling pathway;Epstein-Barr virus infection;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;Alcoholism;Influenza A
85363,0,1,0,28,36,0,4,0,8,151,7,0,TRIM5;tripartite motif containing 5,GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,GO:0070534//protein K63-linked ubiquitination;GO:1902187//negative regulation of viral release from host cell;GO:0046597//negative regulation of viral entry into host cell;GO:0031664//regulation of lipopolysaccharide-mediated signaling pathway;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0002218//activation of innate immune response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0002221//pattern recognition receptor signaling pathway;GO:0043410//positive regulation of MAPK cascade;GO:0051607//defense response to virus;GO:0070206//protein trimerization;GO:0045087//innate immune response;GO:0016032//viral process,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0008329//signaling pattern recognition receptor activity;GO:0008270//zinc ion binding,-
85364,0,7,0,45,6,12,1,74,84,0,45,68,"ZCCHC3;zinc finger, CCHC domain containing 3",-,-,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,-
85365,0,0,0,16,0,12,1,0,10,0,0,0,"ALG2;ALG2, alpha-1,3/1,6-mannosyltransferase",GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0043687//post-translational protein modification;GO:0033577//protein glycosylation in endoplasmic reticulum;GO:0097502//mannosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0051592//response to calcium ion;GO:0006488//dolichol-linked oligosaccharide biosynthetic process,"GO:0005515//protein binding;GO:0000033//alpha-1,3-mannosyltransferase activity;GO:0046982//protein heterodimerization activity;GO:0048306//calcium-dependent protein binding;GO:0004378//GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity;GO:0033164//glycolipid 6-alpha-mannosyltransferase activity;GO:0047485//protein N-terminus binding;GO:0043495//protein anchor",K03843//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis
85366,0,0,0,0,0,8,30,0,49,0,0,0,MYLK2;myosin light chain kinase 2,GO:0030017//sarcomere;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0010628//positive regulation of gene expression;GO:0018107//peptidyl-threonine phosphorylation;GO:0032971//regulation of muscle filament sliding;GO:0055008//cardiac muscle tissue morphogenesis;GO:0014816//skeletal muscle satellite cell differentiation;GO:0046777//protein autophosphorylation;GO:0060048//cardiac muscle contraction;GO:0035914//skeletal muscle cell differentiation;GO:0007274//neuromuscular synaptic transmission;GO:0006941//striated muscle contraction,GO:0005524//ATP binding;GO:0004683//calmodulin-dependent protein kinase activity;GO:0005516//calmodulin binding;GO:0004687//myosin light chain kinase activity;GO:0005515//protein binding,K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
85369,1,25,0,0,4,0,0,0,43,161,0,0,STRIP1;striatin interacting protein 1,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0022604//regulation of cell morphogenesis;GO:0030866//cortical actin cytoskeleton organization,GO:0005515//protein binding,-
8537,0,11,1,40,147,38,0,0,11,0,0,0,BCAS1;breast carcinoma amplified sequence 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K07436//Steroid biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
85371,0,125,87,66,24,17,0,406,208,52,31,302,KIAA1656;KIAA1656 protein,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism
85376,88,0,0,0,0,0,0,0,13,0,0,0,RIMBP3;RIMS binding protein 3,-,-,-,-
85377,84,0,0,0,13,15,14,0,31,131,26,0,MICALL1;MICAL-like 1,GO:0031902//late endosome membrane;GO:0019898//extrinsic component of membrane;GO:0005802//trans-Golgi network;GO:0005769//early endosome;GO:0055038//recycling endosome membrane;GO:0005770//late endosome,"GO:0097320//membrane tubulation;GO:0032458//slow endocytic recycling;GO:1990126//retrograde transport, endosome to plasma membrane;GO:0006898//receptor-mediated endocytosis;GO:0006897//endocytosis;GO:0031175//neuron projection development;GO:0006612//protein targeting to membrane;GO:0036010//protein localization to endosome",GO:0017137//Rab GTPase binding;GO:0070300//phosphatidic acid binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0008270//zinc ion binding,K05699//Focal adhesion;Amoebiasis;Adherens junction;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
85378,55,0,15,12,2,0,2,0,16,1,32,380,"TUBGCP6;tubulin, gamma complex associated protein 6",GO:0005813//centrosome;GO:0008274//gamma-tubulin ring complex;GO:0000922//spindle pole;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0007020//microtubule nucleation;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle,GO:0008017//microtubule binding,K01769//Purine metabolism
85379,122,61,1,11,126,59,22,0,74,0,7,0,KIAA1671;KIAA1671,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
8538,78,0,0,0,0,18,26,0,38,0,0,0,BARX2;BARX homeobox 2,GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001502//cartilage condensation;GO:0042637//catagen;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0014902//myotube differentiation",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0003677//DNA binding;GO:0003682//chromatin binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
8539,0,46,23,41,132,0,31,0,44,11,28,0,API5;apoptosis inhibitor 5,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005681//spliceosomal complex;GO:0016020//membrane,GO:0043066//negative regulation of apoptotic process;GO:2000270//negative regulation of fibroblast apoptotic process;GO:0006915//apoptotic process,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding,-
85395,58,0,0,0,0,22,20,0,9,0,0,5,"FAM207A;family with sequence similarity 207, member A",-,-,-,-
85397,0,0,0,0,0,11,0,0,0,0,0,0,RGS8;regulator of G-protein signaling 8,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K07524//Axon guidance
8540,0,0,1,0,33,0,51,0,114,0,0,0,AGPS;alkylglycerone phosphate synthase,GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0005730//nucleolus;GO:0005778//peroxisomal membrane;GO:0005782//peroxisomal matrix;GO:0005777//peroxisome,GO:0008611//ether lipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008610//lipid biosynthetic process;GO:0055114//oxidation-reduction process;GO:0044255//cellular lipid metabolic process,GO:0008609//alkylglycerone-phosphate synthase activity;GO:0071949//FAD binding;GO:0008762//UDP-N-acetylmuramate dehydrogenase activity,K00803//Metabolic pathways;Peroxisome;Ether lipid metabolism
85403,16,47,21,49,232,0,0,56,22,0,15,0,EAF1;ELL associated factor 1,GO:0005730//nucleolus;GO:0032783//ELL-EAF complex;GO:0016607//nuclear speck;GO:0008023//transcription elongation factor complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0015030//Cajal body,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,-
85406,0,18,0,64,166,6,54,35,17,1,12,0,"DNAJC14;DnaJ (Hsp40) homolog, subfamily C, member 14",GO:0005789//endoplasmic reticulum membrane;GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0015031//protein transport,-,-
85407,0,0,39,0,1,5,0,0,13,0,0,0,NKD1;naked cuticle homolog 1 (Drosophila),GO:0005737//cytoplasm;GO:0000159//protein phosphatase type 2A complex;GO:0005886//plasma membrane,"GO:0016055//Wnt signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0007525//somatic muscle development;GO:1901233//negative regulation of convergent extension involved in axis elongation;GO:1901231//positive regulation of non-canonical Wnt signaling pathway via JNK cascade;GO:0090249//regulation of cell motility involved in somitogenic axis elongation;GO:0001754//eye photoreceptor cell differentiation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000096//positive regulation of Wnt signaling pathway, planar cell polarity pathway",GO:0030165//PDZ domain binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,K03213//Wnt signaling pathway
85409,0,0,0,0,11,16,0,0,16,0,0,0,NKD2;naked cuticle homolog 2 (Drosophila),GO:0071944//cell periphery;GO:0031410//cytoplasmic vesicle;GO:0016328//lateral plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0048210//Golgi vesicle fusion to target membrane;GO:0072661//protein targeting to plasma membrane;GO:0016055//Wnt signaling pathway;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006887//exocytosis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0010954//positive regulation of protein processing;GO:0090004//positive regulation of establishment of protein localization to plasma membrane,GO:0019838//growth factor binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K03213//Wnt signaling pathway
8541,0,0,51,9,27,0,40,39,39,95,43,0,"PPFIA3;protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3",GO:0009986//cell surface;GO:0005737//cytoplasm;GO:0048786//presynaptic active zone,GO:0007165//signal transduction;GO:0007160//cell-matrix adhesion,GO:0005515//protein binding,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
85413,0,27,0,0,0,0,0,0,37,0,2,0,"SLC22A16;solute carrier family 22 (organic cation/carnitine transporter), member 16",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0046717//acid secretion;GO:0015837//amine transport;GO:0007283//spermatogenesis;GO:0055085//transmembrane transport;GO:0030317//sperm motility;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0015695//organic cation transport;GO:1902603//carnitine transmembrane transport;GO:0015879//carnitine transport;GO:0007338//single fertilization,GO:0005275//amine transmembrane transporter activity;GO:0015226//carnitine transmembrane transporter activity;GO:0015101//organic cation transmembrane transporter activity,-
85414,0,41,2,33,135,8,0,3,13,76,21,1,"SLC45A3;solute carrier family 45, member 3",GO:0016021//integral component of membrane,GO:0055085//transmembrane transport,-,K15379//Transcriptional misregulation in cancer
85415,0,2,1,37,157,42,71,0,7,1,0,0,"RHPN2;rhophilin, Rho GTPase binding protein 2",GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0007165//signal transduction,-,-
85416,0,0,0,0,6,0,0,0,21,36,0,0,ZIC5;Zic family member 5,GO:0005634//nucleus,"GO:0001843//neural tube closure;GO:0006355//regulation of transcription, DNA-templated;GO:0030900//forebrain development;GO:0030154//cell differentiation",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
85417,0,0,0,0,16,44,34,0,11,0,7,0,CCNB3;cyclin B3,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007126//meiotic nuclear division;GO:0010389//regulation of G2/M transition of mitotic cell cycle,GO:0005515//protein binding;GO:0019901//protein kinase binding,K05868//Oocyte meiosis;HTLV-I infection;p53 signaling pathway;Progesterone-mediated oocyte maturation;Cell cycle
8542,0,0,0,0,0,0,0,1,10,0,12,0,"APOL1;apolipoprotein L, 1",GO:0005615//extracellular space;GO:0034361//very-low-density lipoprotein particle;GO:0072562//blood microparticle;GO:0005576//extracellular region;GO:0031224//intrinsic component of membrane;GO:0034364//high-density lipoprotein particle,GO:0045087//innate immune response;GO:0042157//lipoprotein metabolic process;GO:1902476//chloride transmembrane transport;GO:0031640//killing of cells of other organism;GO:0006821//chloride transport;GO:0019835//cytolysis;GO:0008203//cholesterol metabolic process;GO:0006869//lipid transport,GO:0005515//protein binding;GO:0005254//chloride channel activity;GO:0008289//lipid binding,K14480//African trypanosomiasis
8543,18,0,0,0,40,13,0,0,41,4,4,0,LMO4;LIM domain only 4,GO:0005667//transcription factor complex,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0003281//ventricular septum development;GO:0048538//thymus development;GO:0021514//ventral spinal cord interneuron differentiation;GO:0050865//regulation of cell activation;GO:0001843//neural tube closure;GO:0042659//regulation of cell fate specification;GO:0031333//negative regulation of protein complex assembly;GO:0006366//transcription from RNA polymerase II promoter;GO:0021522//spinal cord motor neuron differentiation;GO:0021527//spinal cord association neuron differentiation,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0008270//zinc ion binding,K15612//Transcriptional misregulation in cancer
85437,0,0,0,19,66,8,0,0,0,0,0,0,ZCRB1;zinc finger CCHC-type and RNA binding motif 1,GO:0005689//U12-type spliceosomal complex;GO:0005654//nucleoplasm,GO:0008380//RNA splicing;GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
85438,0,0,1,0,0,0,0,0,0,0,8,0,"CABS1;calcium-binding protein, spermatid-specific 1",GO:0005743//mitochondrial inner membrane;GO:0031514//motile cilium,GO:0007283//spermatogenesis,GO:0005509//calcium ion binding,-
85439,1,0,1,8,103,22,0,36,143,169,11,0,STON2;stonin 2,GO:0005737//cytoplasm;GO:0030131//clathrin adaptor complex;GO:0030054//cell junction;GO:0005730//nucleolus;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0030136//clathrin-coated vesicle,GO:0048488//synaptic vesicle endocytosis;GO:0002244//hematopoietic progenitor cell differentiation;GO:0006886//intracellular protein transport;GO:0030100//regulation of endocytosis,GO:0005515//protein binding,K11826//Synaptic vesicle cycle;Endocrine and other factor-regulated calcium reabsorption;Endocytosis;Huntington's disease;K12393//Lysosome;K11447//Transcriptional misregulation in cancer
8544,0,0,0,9,0,0,0,0,0,0,0,0,PIR;pirin (iron-binding nuclear protein),GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0055114//oxidation-reduction process;GO:0030224//monocyte differentiation","GO:0008127//quercetin 2,3-dioxygenase activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003712//transcription cofactor activity",-
85440,0,26,1,5,157,22,21,0,16,0,7,0,DOCK7;dedicator of cytokinesis 7,GO:0043005//neuron projection;GO:0008180//COP9 signalosome;GO:0030424//axon;GO:0005925//focal adhesion;GO:0030426//growth cone;GO:0045178//basal part of cell,GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0000226//microtubule cytoskeleton organization;GO:0050767//regulation of neurogenesis;GO:0031175//neuron projection development;GO:0007409//axonogenesis;GO:0045200//establishment of neuroblast polarity;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043473//pigmentation;GO:0032863//activation of Rac GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0022027//interkinetic nuclear migration,GO:0048365//Rac GTPase binding;GO:0005085//guanyl-nucleotide exchange factor activity,-
85441,154,0,0,0,0,0,1,162,13,0,2,0,"HELZ2;helicase with zinc finger 2, transcriptional coactivator",GO:0005654//nucleoplasm;GO:0016020//membrane,"GO:0044281//small molecule metabolic process;GO:0044255//cellular lipid metabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0005524//ATP binding,K14326//mRNA surveillance pathway;RNA transport
85442,132,0,0,0,0,0,0,84,128,0,15,0,KNDC1;kinase non-catalytic C-lobe domain (KIND) containing 1,GO:0030425//dendrite;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0043025//neuronal cell body,GO:0048814//regulation of dendrite morphogenesis;GO:0032320//positive regulation of Ras GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0001934//positive regulation of protein phosphorylation;GO:0021707//cerebellar granule cell differentiation;GO:0006468//protein phosphorylation,GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0004674//protein serine/threonine kinase activity,K08018//MAPK signaling pathway
85443,0,0,0,3,0,12,0,8,37,0,0,0,DCLK3;doublecortin-like kinase 3,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
85444,24,0,0,0,19,33,0,43,28,0,4,0,LRRCC1;leucine rich repeat and coiled-coil centrosomal protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005730//nucleolus;GO:0005814//centriole,GO:0007067//mitotic nuclear division,-,K04437//Salmonella infection;MAPK signaling pathway;Focal adhesion;K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K03257//RNA transport
85445,0,0,36,0,0,33,39,0,36,0,5,0,CNTNAP4;contactin associated protein-like 4,GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0030425//dendrite,"GO:2000821//regulation of grooming behavior;GO:0032228//regulation of synaptic transmission, GABAergic;GO:0032225//regulation of synaptic transmission, dopaminergic;GO:0007155//cell adhesion",-,K07380//Cell adhesion molecules (CAMs)
85446,0,0,1,0,0,26,0,44,90,0,9,0,ZFHX2;zinc finger homeobox 2,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030534//adult behavior;GO:0006351//transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0008270//zinc ion binding,-
85449,0,0,0,0,0,11,0,6,56,0,1,202,KIAA1755;KIAA1755,-,-,-,-
8545,0,39,0,33,204,17,0,0,18,10,26,0,CGGBP1;CGG triplet repeat binding protein 1,GO:0005730//nucleolus;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0003690//double-stranded DNA binding;GO:0001227//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
85450,0,0,0,0,0,0,22,0,13,58,13,0,"ITPRIP;inositol 1,4,5-trisphosphate receptor interacting protein",GO:0016020//membrane;GO:0005886//plasma membrane,-,-,-
85451,19,0,0,9,35,23,0,65,92,1,0,0,UNK;unkempt family zinc finger,-,-,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,K13056//Oocyte meiosis
85453,0,1,0,25,109,1,0,0,13,0,12,0,TSPYL5;TSPY-like 5,GO:0005634//nucleus,GO:0071480//cellular response to gamma radiation;GO:0031398//positive regulation of protein ubiquitination;GO:0051897//positive regulation of protein kinase B signaling;GO:0006334//nucleosome assembly;GO:0008284//positive regulation of cell proliferation;GO:0040008//regulation of growth,GO:0005515//protein binding,-
85455,0,0,0,0,0,21,0,48,57,0,6,0,DISP2;dispatched homolog 2 (Drosophila),GO:0016021//integral component of membrane,GO:0007224//smoothened signaling pathway,-,-
85456,141,1,0,0,1,34,21,1,32,0,11,0,"TNKS1BP1;tankyrase 1 binding protein 1, 182kDa",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0030014//CCR4-NOT complex;GO:0005724//nuclear telomeric heterochromatin;GO:0005829//cytosol,"GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0016071//mRNA metabolic process;GO:0007004//telomere maintenance via telomerase;GO:0016070//RNA metabolic process;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening",GO:0019899//enzyme binding;GO:0030506//ankyrin binding,-
85457,0,63,0,27,75,0,0,0,19,0,26,0,CIPC;CLOCK-interacting pacemaker,GO:0005634//nucleus,"GO:0042754//negative regulation of circadian rhythm;GO:0048511//rhythmic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
85458,56,0,0,7,22,0,15,10,107,95,0,0,DIXDC1;DIX domain containing 1,GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0043234//protein complex;GO:0043679//axon terminus;GO:0043025//neuronal cell body;GO:0005938//cell cortex,"GO:0046328//regulation of JNK cascade;GO:0032956//regulation of actin cytoskeleton organization;GO:0030900//forebrain development;GO:0046330//positive regulation of JNK cascade;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0045665//negative regulation of neuron differentiation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0043010//camera-type eye development;GO:0021869//forebrain ventricular zone progenitor cell division;GO:0021695//cerebellar cortex development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0021799//cerebral cortex radially oriented cell migration;GO:0007049//cell cycle;GO:0050772//positive regulation of axonogenesis",GO:0019904//protein domain specific binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0003779//actin binding;GO:0043015//gamma-tubulin binding;GO:0005515//protein binding,K10366//Viral myocarditis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy;K05699//Systemic lupus erythematosus;Regulation of actin cytoskeleton;Adherens junction;Focal adhesion;Amoebiasis;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Leukocyte transendothelial migration;K02353//Basal cell carcinoma;Melanogenesis;Notch signaling pathway;Pathways in cancer;Wnt signaling pathway;HTLV-I infection
85459,1,0,4,0,8,35,15,0,102,0,1,0,KIAA1731;KIAA1731,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,-,-,-
8546,0,0,2,20,59,0,0,0,61,0,1,0,"AP3B1;adaptor-related protein complex 3, beta 1 subunit",GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0005765//lysosomal membrane;GO:0030123//AP-3 adaptor complex;GO:0030665//clathrin-coated vesicle membrane,"GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0008089//anterograde axon cargo transport;GO:0006886//intracellular protein transport;GO:0051138//positive regulation of NK T cell differentiation;GO:0007596//blood coagulation;GO:0032438//melanosome organization;GO:0048490//anterograde synaptic vesicle transport;GO:0006622//protein targeting to lysosome",GO:0030742//GTP-dependent protein binding;GO:0019903//protein phosphatase binding,K12397//Lysosome
85460,92,2,1,42,120,2,0,0,33,47,0,0,ZNF518B;zinc finger protein 518B,GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
85461,0,0,0,46,79,23,4,0,36,70,0,0,"TANC1;tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1",GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0043679//axon terminus,GO:0097062//dendritic spine maintenance;GO:0007520//myoblast fusion;GO:0008542//visual learning,-,-
85462,0,16,0,12,22,4,56,0,66,226,0,329,FHDC1;FH2 domain containing 1,-,-,-,K04512//Wnt signaling pathway
85463,0,16,22,2,2,10,1,60,41,0,0,0,ZC3H12C;zinc finger CCCH-type containing 12C,-,GO:0090305//nucleic acid phosphodiester bond hydrolysis,GO:0004519//endonuclease activity;GO:0046872//metal ion binding,-
85464,95,22,0,0,15,29,26,29,19,0,5,0,SSH2;slingshot protein phosphatase 2,GO:0005615//extracellular space;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0030036//actin cytoskeleton organization;GO:0006470//protein dephosphorylation;GO:0008064//regulation of actin polymerization or depolymerization;GO:0010591//regulation of lamellipodium assembly;GO:0050770//regulation of axonogenesis,GO:0003779//actin binding;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0003677//DNA binding;GO:0004721//phosphoprotein phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K05766//Regulation of actin cytoskeleton
85465,0,0,0,7,26,17,44,0,96,0,0,0,EPT1;ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006646//phosphatidylethanolamine biosynthetic process,GO:0046872//metal ion binding;GO:0004307//ethanolaminephosphotransferase activity,K00993//Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
8547,0,0,0,0,0,0,0,2,0,9,0,0,FCN3;ficolin (collagen/fibrinogen domain containing) 3,GO:0005581//collagen trimer;GO:0072562//blood microparticle;GO:0005576//extracellular region,"GO:0001867//complement activation, lectin pathway;GO:0006956//complement activation;GO:0045087//innate immune response",GO:0005515//protein binding;GO:0030246//carbohydrate binding,-
85474,0,0,0,0,0,0,19,0,26,0,0,0,LBX2;ladybird homeobox 2,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding,-
85476,0,61,0,32,88,0,17,0,14,0,0,0,"GFM1;G elongation factor, mitochondrial 1",GO:0005739//mitochondrion,GO:0070125//mitochondrial translational elongation;GO:0006184//GTP catabolic process,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003746//translation elongation factor activity;GO:0005525//GTP binding;GO:0003924//GTPase activity,-
85477,0,1,0,11,1,17,0,0,1,57,0,0,SCIN;scinderin,GO:0070062//extracellular vesicular exosome;GO:0043234//protein complex;GO:0005856//cytoskeleton;GO:0005938//cell cortex;GO:0005737//cytoplasm,GO:0032330//regulation of chondrocyte differentiation;GO:0051014//actin filament severing;GO:0045654//positive regulation of megakaryocyte differentiation;GO:0045010//actin nucleation;GO:0043065//positive regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0051693//actin filament capping;GO:0017156//calcium ion-dependent exocytosis;GO:0051047//positive regulation of secretion,"GO:0005545//1-phosphatidylinositol binding;GO:0051015//actin filament binding;GO:0001786//phosphatidylserine binding;GO:0005509//calcium ion binding;GO:0003779//actin binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K05768//Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis
85478,0,0,0,0,4,3,42,0,0,0,0,0,CCDC65;coiled-coil domain containing 65,-,-,-,K12478//Tuberculosis;Endocytosis;Phagosome;K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
85479,0,0,26,0,0,0,26,0,0,0,6,0,"DNAJC5B;DnaJ (Hsp40) homolog, subfamily C, member 5 beta",GO:0016020//membrane,-,-,K09525//Protein processing in endoplasmic reticulum
8548,10,12,0,0,49,0,0,0,24,0,0,0,BLZF1;basic leucine zipper nuclear factor 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000139//Golgi membrane;GO:0005796//Golgi lumen;GO:0005730//nucleolus,GO:0007030//Golgi organization;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0000278//mitotic cell cycle;GO:0001558//regulation of cell growth;GO:0008283//cell proliferation;GO:0043001//Golgi to plasma membrane protein transport,GO:0019899//enzyme binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0031625//ubiquitin protein ligase binding;GO:0003677//DNA binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer
85480,0,0,0,0,0,0,38,0,17,0,0,0,TSLP;thymic stromal lymphopoietin,GO:0005615//extracellular space,-,GO:0005125//cytokine activity,K05436//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
85481,0,0,0,0,0,0,0,0,7,0,9,0,PSKH2;protein serine kinase H2,-,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
8549,0,0,0,0,0,42,5,0,15,0,0,0,LGR5;leucine-rich repeat containing G protein-coupled receptor 5,GO:0005887//integral component of plasma membrane;GO:0032588//trans-Golgi network membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0048839//inner ear development;GO:0090263//positive regulation of canonical Wnt signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity,-
85495,0,222,7,124,131,0,0,3,0,0,1,0,RPPH1;ribonuclease P RNA component H1,-,-,-,-
8550,100,4,0,7,65,2,0,0,0,0,1,0,MAPKAPK5;mitogen-activated protein kinase-activated protein kinase 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005730//nucleolus,GO:0046777//protein autophosphorylation;GO:0007265//Ras protein signal transduction;GO:0007165//signal transduction;GO:0090400//stress-induced premature senescence;GO:0006417//regulation of translation;GO:0032007//negative regulation of TOR signaling;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade,GO:0005515//protein binding;GO:0004708//MAP kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0002039//p53 binding;GO:0051019//mitogen-activated protein kinase binding;GO:0005524//ATP binding,K04442//MAPK signaling pathway
85508,58,0,0,0,0,0,27,0,0,0,0,0,SCRT2;scratch family zinc finger 2,GO:0000790//nuclear chromatin,"GO:2001222//regulation of neuron migration;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
85509,0,0,0,0,0,0,0,0,17,0,0,0,MBD3L1;methyl-CpG binding domain protein 3-like 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005886//plasma membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
8553,0,0,0,0,41,0,0,6,55,0,0,0,"BHLHE40;basic helix-loop-helix family, member e40",GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0043153//entrainment of circadian clock by photoperiod;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0032922//circadian regulation of gene expression;GO:0006366//transcription from RNA polymerase II promoter",GO:0070888//E-box binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0043426//MRF binding;GO:0003714//transcription corepressor activity;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0019904//protein domain specific binding;GO:0043425//bHLH transcription factor binding;GO:0001191//RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription,K03729//Circadian rhythm - mammal
8554,0,0,0,0,10,37,7,0,12,0,20,0,"PIAS1;protein inhibitor of activated STAT, 1",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0016607//nuclear speck,"GO:0006351//transcription, DNA-templated;GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0016925//protein sumoylation;GO:0019221//cytokine-mediated signaling pathway;GO:0033235//positive regulation of protein sumoylation;GO:0065004//protein-DNA complex assembly;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007283//spermatogenesis;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0042127//regulation of cell proliferation;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007259//JAK-STAT cascade",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0019899//enzyme binding;GO:0019904//protein domain specific binding;GO:0019789//SUMO ligase activity;GO:0003677//DNA binding;GO:0031625//ubiquitin protein ligase binding;GO:0050681//androgen receptor binding,K04706//Hepatitis C;Jak-STAT signaling pathway;Ubiquitin mediated proteolysis
8555,0,13,0,39,56,1,0,3,17,0,0,0,CDC14B;cell division cycle 14B,GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005634//nucleus,GO:0031572//G2 DNA damage checkpoint;GO:0006281//DNA repair;GO:0051488//activation of anaphase-promoting complex activity;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity,K06639//Cell cycle;Cell cycle - yeast;Meiosis - yeast
8556,142,0,0,7,11,42,0,0,23,0,0,0,CDC14A;cell division cycle 14A,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle,GO:0007049//cell cycle;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0051301//cell division;GO:0008283//cell proliferation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0004721//phosphoprotein phosphatase activity,K06639//Meiosis - yeast;Cell cycle;Cell cycle - yeast
85569,0,0,0,0,0,0,0,37,2,0,0,0,GALP;galanin-like peptide,GO:0005576//extracellular region,GO:0007218//neuropeptide signaling pathway;GO:0042595//behavioral response to starvation;GO:0032868//response to insulin;GO:0042742//defense response to bacterium;GO:0032098//regulation of appetite,GO:0005179//hormone activity,-
8557,0,0,0,0,0,0,0,0,5,135,0,0,TCAP;titin-cap,GO:0005829//cytosol;GO:0030018//Z disc;GO:0031674//I band,GO:0035995//detection of muscle stretch;GO:0035994//response to muscle stretch;GO:0030916//otic vesicle formation;GO:0060048//cardiac muscle contraction;GO:0006461//protein complex assembly;GO:0048739//cardiac muscle fiber development;GO:0001756//somitogenesis;GO:0055003//cardiac myofibril assembly;GO:0045214//sarcomere organization;GO:0055008//cardiac muscle tissue morphogenesis;GO:0003300//cardiac muscle hypertrophy;GO:0003009//skeletal muscle contraction;GO:0030241//skeletal muscle myosin thick filament assembly;GO:0048769//sarcomerogenesis;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0030049//muscle filament sliding;GO:0030240//skeletal muscle thin filament assembly;GO:0050982//detection of mechanical stimulus;GO:0007512//adult heart development,"GO:0031432//titin binding;GO:0051373//FATZ binding;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0030674//protein binding, bridging;GO:0008307//structural constituent of muscle;GO:0070080//titin Z domain binding",-
8558,0,0,0,0,1,2,0,1,0,0,16,0,CDK10;cyclin-dependent kinase 10,-,GO:0007089//traversing start control point of mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0008285//negative regulation of cell proliferation,GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0005515//protein binding,-
8559,0,0,0,9,21,23,0,0,34,0,0,0,PRPF18;pre-mRNA processing factor 18,GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005681//spliceosomal complex,GO:0006397//mRNA processing;GO:0008380//RNA splicing,GO:0019870//potassium channel inhibitor activity,K12817//Spliceosome
8560,0,0,0,0,0,0,22,54,0,0,0,0,"DEGS1;delta(4)-desaturase, sphingolipid 1",GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0044281//small molecule metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0055114//oxidation-reduction process,"GO:0009055//electron carrier activity;GO:0016705//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",K04712//Sphingolipid metabolism;Metabolic pathways
8562,0,52,0,47,100,0,0,0,0,0,2,0,DENR;density-regulated protein,-,GO:0002192//IRES-dependent translational initiation;GO:0032790//ribosome disassembly;GO:0001731//formation of translation preinitiation complex,GO:0003743//translation initiation factor activity;GO:0005515//protein binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K11447//Transcriptional misregulation in cancer
8563,6,11,0,0,9,0,0,1,36,54,6,0,THOC5;THO complex 5,GO:0005730//nucleolus;GO:0000346//transcription export complex;GO:0016607//nuclear speck;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000445//THO complex part of transcription export complex,"GO:0017145//stem cell division;GO:0045650//negative regulation of macrophage differentiation;GO:0030224//monocyte differentiation;GO:0000902//cell morphogenesis;GO:0008380//RNA splicing;GO:0001824//blastocyst development;GO:0006397//mRNA processing;GO:0006406//mRNA export from nucleus;GO:0060215//primitive hemopoiesis;GO:0046784//viral mRNA export from host cell nucleus;GO:2000035//regulation of stem cell division;GO:0010793//regulation of mRNA export from nucleus;GO:2000002//negative regulation of DNA damage checkpoint;GO:0032786//positive regulation of DNA-templated transcription, elongation",GO:0003729//mRNA binding;GO:0005515//protein binding,K13174//RNA transport
8564,0,0,0,35,42,0,18,0,45,0,2,0,KMO;kynurenine 3-monooxygenase (kynurenine 3-hydroxylase),GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005741//mitochondrial outer membrane;GO:0016021//integral component of membrane;GO:0005829//cytosol,GO:0019441//tryptophan catabolic process to kynurenine;GO:0034641//cellular nitrogen compound metabolic process;GO:0009651//response to salt stress;GO:0034354//'de novo' NAD biosynthetic process from tryptophan;GO:0055114//oxidation-reduction process;GO:0043420//anthranilate metabolic process;GO:0044281//small molecule metabolic process;GO:0006569//tryptophan catabolic process;GO:0019805//quinolinate biosynthetic process,GO:0016174//NAD(P)H oxidase activity;GO:0004502//kynurenine 3-monooxygenase activity;GO:0050660//flavin adenine dinucleotide binding,K00486//Tryptophan metabolism;Metabolic pathways
8565,30,57,32,44,48,0,0,79,28,0,82,1,YARS;tyrosyl-tRNA synthetase,GO:0005829//cytosol;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006915//apoptotic process;GO:0006437//tyrosyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0007165//signal transduction;GO:0010467//gene expression,GO:0004831//tyrosine-tRNA ligase activity;GO:0044822//poly(A) RNA binding;GO:0004871//signal transducer activity;GO:0005153//interleukin-8 receptor binding;GO:0005524//ATP binding;GO:0000049//tRNA binding,K01866//ABC transporters;Aminoacyl-tRNA biosynthesis;Peptidoglycan biosynthesis
8566,0,49,4,11,40,42,36,44,45,0,5,0,"PDXK;pyridoxal (pyridoxine, vitamin B6) kinase",GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0009443//pyridoxal 5'-phosphate salvage;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0016310//phosphorylation;GO:0042816//vitamin B6 metabolic process;GO:0006766//vitamin metabolic process;GO:0042823//pyridoxal phosphate biosynthetic process;GO:0008283//cell proliferation,GO:0030955//potassium ion binding;GO:0031402//sodium ion binding;GO:0005524//ATP binding;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding;GO:0008478//pyridoxal kinase activity;GO:0000287//magnesium ion binding;GO:0031403//lithium ion binding;GO:0030170//pyridoxal phosphate binding,K00868//Ribosome;RNA degradation;Metabolic pathways;Vitamin B6 metabolism
8567,9,12,1,0,58,0,0,0,55,190,16,0,MADD;MAP-kinase activating death domain,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:1902041//regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0042981//regulation of apoptotic process;GO:0097194//execution phase of apoptosis;GO:0032851//positive regulation of Rab GTPase activity;GO:0051726//regulation of cell cycle;GO:0007166//cell surface receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:2001236//regulation of extrinsic apoptotic signaling pathway;GO:2001234//negative regulation of apoptotic signaling pathway,GO:0005123//death receptor binding;GO:0030295//protein kinase activator activity;GO:0005515//protein binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
8568,0,0,0,1,1,11,0,0,7,0,0,0,RRP1;ribosomal RNA processing 1,"GO:0005634//nucleus;GO:0030688//preribosome, small subunit precursor;GO:0005730//nucleolus",GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
8569,0,0,40,0,13,0,0,0,30,83,0,0,MKNK1;MAP kinase interacting serine/threonine kinase 1,GO:0005634//nucleus;GO:0005829//cytosol,GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0006468//protein phosphorylation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0009651//response to salt stress;GO:0006417//regulation of translation;GO:0035556//intracellular signal transduction,GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K04372//MAPK signaling pathway;Insulin signaling pathway
857,0,0,0,0,0,0,1,0,0,0,7,0,"CAV1;caveolin 1, caveolae protein, 22kDa",GO:0031410//cytoplasmic vesicle;GO:0043234//protein complex;GO:0016324//apical plasma membrane;GO:0005811//lipid particle;GO:0045121//membrane raft;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005622//intracellular;GO:0002080//acrosomal membrane;GO:0005938//cell cortex;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0005887//integral component of plasma membrane;GO:0005901//caveola;GO:0005929//cilium;GO:0016323//basolateral plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005925//focal adhesion,GO:0000165//MAPK cascade;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0042310//vasoconstriction;GO:0019217//regulation of fatty acid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006874//cellular calcium ion homeostasis;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0071455//cellular response to hyperoxia;GO:0006940//regulation of smooth muscle contraction;GO:0060056//mammary gland involution;GO:0001666//response to hypoxia;GO:0043627//response to estrogen;GO:0031397//negative regulation of protein ubiquitination;GO:0048554//positive regulation of metalloenzyme activity;GO:0055074//calcium ion homeostasis;GO:0070836//caveola assembly;GO:0030857//negative regulation of epithelial cell differentiation;GO:0003057//regulation of the force of heart contraction by chemical signal;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0001960//negative regulation of cytokine-mediated signaling pathway;GO:0032091//negative regulation of protein binding;GO:0032507//maintenance of protein location in cell;GO:0001525//angiogenesis;GO:0048550//negative regulation of pinocytosis;GO:0033484//nitric oxide homeostasis;GO:0042524//negative regulation of tyrosine phosphorylation of Stat5 protein;GO:0050999//regulation of nitric-oxide synthase activity;GO:0007596//blood coagulation;GO:0000188//inactivation of MAPK activity;GO:0042632//cholesterol homeostasis;GO:0051592//response to calcium ion;GO:0007595//lactation;GO:0016032//viral process;GO:0030301//cholesterol transport;GO:0008104//protein localization;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0051260//protein homooligomerization;GO:0031295//T cell costimulation;GO:0044281//small molecule metabolic process;GO:0001570//vasculogenesis;GO:0030193//regulation of blood coagulation;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006641//triglyceride metabolic process;GO:0030879//mammary gland development;GO:0032570//response to progesterone;GO:0050900//leukocyte migration;GO:0030514//negative regulation of BMP signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:2000811//negative regulation of anoikis;GO:0002931//response to ischemia;GO:0006816//calcium ion transport;GO:0016050//vesicle organization;GO:0051480//cytosolic calcium ion homeostasis;GO:0046209//nitric oxide metabolic process;GO:2000286//receptor internalization involved in canonical Wnt signaling pathway;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0007519//skeletal muscle tissue development;GO:0046426//negative regulation of JAK-STAT cascade;GO:0019915//lipid storage;GO:0010952//positive regulation of peptidase activity;GO:0045907//positive regulation of vasoconstriction;GO:0097190//apoptotic signaling pathway;GO:0072584//caveolin-mediated endocytosis;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0051899//membrane depolarization;GO:0043409//negative regulation of MAPK cascade;GO:0010524//positive regulation of calcium ion transport into cytosol;GO:0009267//cellular response to starvation,GO:0005198//structural molecule activity;GO:0015485//cholesterol binding;GO:0019899//enzyme binding;GO:0050998//nitric-oxide synthase binding;GO:0016504//peptidase activator activity;GO:0005113//patched binding;GO:0005515//protein binding;GO:0005102//receptor binding;GO:0032947//protein complex scaffold,K06278//Focal adhesion;Bacterial invasion of epithelial cells;Endocytosis;Viral myocarditis
8570,0,33,1,3,47,0,0,57,100,0,9,0,KHSRP;KH-type splicing regulatory protein,GO:0005654//nucleoplasm;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0016020//membrane;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:2000628//regulation of miRNA metabolic process;GO:0006351//transcription, DNA-templated;GO:0000375//RNA splicing, via transesterification reactions;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0006402//mRNA catabolic process;GO:0051028//mRNA transport;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process",GO:0003677//DNA binding;GO:0003729//mRNA binding;GO:0044822//poly(A) RNA binding,-
8572,0,0,3,0,0,20,13,0,54,0,0,0,PDLIM4;PDZ and LIM domain 4,-,-,GO:0005515//protein binding;GO:0008270//zinc ion binding,K05760//Leukocyte transendothelial migration;Focal adhesion;VEGF signaling pathway;Chemokine signaling pathway;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;K05743//Fc gamma R-mediated phagocytosis;Regulation of actin cytoskeleton;Axon guidance
8573,0,0,0,6,27,49,0,0,11,0,0,0,CASK;calcium/calmodulin-dependent serine protein kinase (MAGUK family),GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0005652//nuclear lamina;GO:0060170//ciliary membrane;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0016363//nuclear matrix;GO:0005925//focal adhesion;GO:0005730//nucleolus;GO:0016323//basolateral plasma membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005604//basement membrane,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090288//negative regulation of cellular response to growth factor stimulus;GO:0030198//extracellular matrix organization;GO:0070509//calcium ion import;GO:0001953//negative regulation of cell-matrix adhesion;GO:0046939//nucleotide phosphorylation;GO:0090280//positive regulation of calcium ion import;GO:0006468//protein phosphorylation;GO:0061045//negative regulation of wound healing;GO:0007155//cell adhesion;GO:0010839//negative regulation of keratinocyte proliferation,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0042043//neurexin family protein binding;GO:0004385//guanylate kinase activity;GO:0005524//ATP binding;GO:0005516//calmodulin binding,K06103//Tight junction
8574,0,0,0,6,33,0,0,0,14,0,0,0,"AKR7A2;aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)",GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:0005975//carbohydrate metabolic process;GO:0044597//daunorubicin metabolic process;GO:0006081//cellular aldehyde metabolic process;GO:0044598//doxorubicin metabolic process,"GO:0019119//phenanthrene-9,10-epoxide hydrolase activity;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0009055//electron carrier activity",K15303//Metabolism of xenobiotics by cytochrome P450
8575,209,0,74,16,24,0,0,0,17,0,8,0,"PRKRA;protein kinase, interferon-inducible double stranded RNA dependent activator",GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0048705//skeletal system morphogenesis;GO:0042474//middle ear morphogenesis;GO:0034599//cellular response to oxidative stress;GO:0010467//gene expression;GO:0008285//negative regulation of cell proliferation;GO:0009615//response to virus;GO:0006468//protein phosphorylation;GO:0043085//positive regulation of catalytic activity;GO:0042473//outer ear morphogenesis;GO:0006955//immune response;GO:0030422//production of siRNA involved in RNA interference;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway,GO:0008047//enzyme activator activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12968//Influenza A;Measles;Cytosolic DNA-sensing pathway
8576,0,12,1,1,1,13,59,0,0,0,0,0,STK16;serine/threonine kinase 16,GO:0048471//perinuclear region of cytoplasm;GO:0005798//Golgi-associated vesicle;GO:0016020//membrane,GO:0018108//peptidyl-tyrosine phosphorylation;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0046777//protein autophosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005524//ATP binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
8577,0,0,0,0,0,0,0,0,13,0,0,0,TMEFF1;transmembrane protein with EGF-like and two follistatin-like domains 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007275//multicellular organismal development,-,K06254//ECM-receptor interaction
8578,58,0,0,0,0,29,0,0,5,0,0,0,"SCARF1;scavenger receptor class F, member 1",GO:0030666//endocytic vesicle membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0010976//positive regulation of neuron projection development;GO:0006707//cholesterol catabolic process;GO:0016322//neuron remodeling;GO:0007165//signal transduction;GO:0016358//dendrite development;GO:0048680//positive regulation of axon regeneration;GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis,GO:0004888//transmembrane signaling receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0005044//scavenger receptor activity,K06252//ECM-receptor interaction;Focal adhesion;K06243//Pathways in cancer;Toxoplasmosis;ECM-receptor interaction;Amoebiasis;Small cell lung cancer;Focal adhesion
858,32,0,0,0,0,0,48,0,0,166,0,0,CAV2;caveolin 2,GO:0016020//membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0002080//acrosomal membrane;GO:0030133//transport vesicle;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005901//caveola;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005811//lipid particle;GO:0045121//membrane raft;GO:0043234//protein complex;GO:0031410//cytoplasmic vesicle;GO:0005622//intracellular;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm,GO:0001937//negative regulation of endothelial cell proliferation;GO:0007005//mitochondrion organization;GO:0007088//regulation of mitosis;GO:0070836//caveola assembly;GO:0048741//skeletal muscle fiber development;GO:0048278//vesicle docking;GO:0051259//protein oligomerization;GO:0007268//synaptic transmission;GO:0001938//positive regulation of endothelial cell proliferation;GO:0016050//vesicle organization;GO:0060161//positive regulation of dopamine receptor signaling pathway;GO:0007029//endoplasmic reticulum organization;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006906//vesicle fusion,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0051219//phosphoprotein binding;GO:0019905//syntaxin binding;GO:0031748//D1 dopamine receptor binding,K12958//Bacterial invasion of epithelial cells;Endocytosis;Focal adhesion
8581,0,0,0,0,0,3,0,0,0,0,0,0,"LY6D;lymphocyte antigen 6 complex, locus D",GO:0005886//plasma membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0031225//anchored component of membrane,GO:0035634//response to stilbenoid;GO:0030098//lymphocyte differentiation;GO:0007155//cell adhesion,-,-
85865,78,0,0,12,32,0,31,0,61,0,14,0,GTPBP10;GTP-binding protein 10 (putative),GO:0005730//nucleolus;GO:0005694//chromosome;GO:0005739//mitochondrion,GO:0006184//GTP catabolic process;GO:0042254//ribosome biogenesis,GO:0044822//poly(A) RNA binding;GO:0005525//GTP binding;GO:0000287//magnesium ion binding;GO:0003924//GTPase activity,-
8587,0,0,33,0,0,0,0,0,0,0,0,0,"OR7E2P;olfactory receptor, family 7, subfamily E, member 2 pseudogene",-,-,-,K04257//Olfactory transduction
859,0,0,13,0,0,0,0,54,1,0,0,0,CAV3;caveolin 3,GO:0030018//Z disc;GO:0031982//vesicle;GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0030315//T-tubule;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0016010//dystrophin-associated glycoprotein complex;GO:0031594//neuromuscular junction;GO:0005886//plasma membrane;GO:0005901//caveola;GO:0042383//sarcolemma,GO:0046716//muscle cell cellular homeostasis;GO:0043407//negative regulation of MAP kinase activity;GO:0010831//positive regulation of myotube differentiation;GO:0006641//triglyceride metabolic process;GO:0002027//regulation of heart rate;GO:0038009//regulation of signal transduction by receptor internalization;GO:0060762//regulation of branching involved in mammary gland duct morphogenesis;GO:1900825//regulation of membrane depolarization during cardiac muscle cell action potential;GO:0051394//regulation of nerve growth factor receptor activity;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0090002//establishment of protein localization to plasma membrane;GO:0051647//nucleus localization;GO:0030154//cell differentiation;GO:0070836//caveola assembly;GO:0033292//T-tubule organization;GO:0045792//negative regulation of cell size;GO:0055013//cardiac muscle cell development;GO:0031579//membrane raft organization;GO:2001288//positive regulation of caveolin-mediated endocytosis;GO:2000649//regulation of sodium ion transmembrane transporter activity;GO:0008016//regulation of heart contraction;GO:0072659//protein localization to plasma membrane;GO:0060347//heart trabecula formation;GO:0008104//protein localization;GO:0051896//regulation of protein kinase B signaling;GO:0042391//regulation of membrane potential;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0051001//negative regulation of nitric-oxide synthase activity;GO:0031122//cytoplasmic microtubule organization;GO:1901019//regulation of calcium ion transmembrane transporter activity;GO:0006469//negative regulation of protein kinase activity;GO:0006897//endocytosis;GO:0042632//cholesterol homeostasis;GO:0001778//plasma membrane repair;GO:0014819//regulation of skeletal muscle contraction;GO:0007520//myoblast fusion;GO:0060373//regulation of ventricular cardiac muscle cell membrane depolarization;GO:0090279//regulation of calcium ion import;GO:0007517//muscle organ development;GO:1900744//regulation of p38MAPK cascade;GO:0007015//actin filament organization;GO:2000060//positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:0051926//negative regulation of calcium ion transport;GO:0043409//negative regulation of MAPK cascade;GO:0060299//negative regulation of sarcomere organization;GO:0007009//plasma membrane organization;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0031116//positive regulation of microtubule polymerization;GO:0016049//cell growth;GO:2000009//negative regulation of protein localization to cell surface;GO:0042593//glucose homeostasis;GO:0008284//positive regulation of cell proliferation;GO:0010614//negative regulation of cardiac muscle hypertrophy;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0061052//negative regulation of cell growth involved in cardiac muscle cell development;GO:0086005//ventricular cardiac muscle cell action potential;GO:0055117//regulation of cardiac muscle contraction,GO:0017080//sodium channel regulator activity;GO:0071253//connexin binding;GO:0050998//nitric-oxide synthase binding;GO:0005246//calcium channel regulator activity;GO:0032403//protein complex binding;GO:0019870//potassium channel inhibitor activity;GO:0044325//ion channel binding;GO:0043014//alpha-tubulin binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0032947//protein complex scaffold,K12959//Bacterial invasion of epithelial cells;Endocytosis;Focal adhesion
8590,0,0,0,0,0,0,0,0,30,0,0,0,"OR6A2;olfactory receptor, family 6, subfamily A, member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0007165//signal transduction;GO:0050911//detection of chemical stimulus involved in sensory perception of smell;GO:0007608//sensory perception of smell,GO:0004930//G-protein coupled receptor activity;GO:0004984//olfactory receptor activity,K04257//Olfactory transduction
86,0,0,0,0,56,0,0,0,21,0,0,0,ACTL6A;actin-like 6A,GO:0005886//plasma membrane;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0071564//npBAF complex;GO:0016514//SWI/SNF complex;GO:0031011//Ino80 complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex,"GO:0003407//neural retina development;GO:0043967//histone H4 acetylation;GO:0006310//DNA recombination;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0006281//DNA repair;GO:0043044//ATP-dependent chromatin remodeling;GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0006338//chromatin remodeling;GO:0043968//histone H2A acetylation;GO:0007399//nervous system development;GO:0006325//chromatin organization",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0003682//chromatin binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0005515//protein binding,-
860,0,1,0,0,15,11,0,9,52,0,0,0,RUNX2;runt-related transcription factor 2,GO:0005667//transcription factor complex;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:1901522//positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus;GO:0042475//odontogenesis of dentin-containing tooth;GO:0001958//endochondral ossification;GO:0001649//osteoblast differentiation;GO:0048863//stem cell differentiation;GO:0035115//embryonic forelimb morphogenesis;GO:0002051//osteoblast fate commitment;GO:0045892//negative regulation of transcription, DNA-templated;GO:0002076//osteoblast development;GO:0002063//chondrocyte development;GO:0048701//embryonic cranial skeleton morphogenesis;GO:0001503//ossification;GO:0008284//positive regulation of cell proliferation;GO:0048469//cell maturation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0040036//regulation of fibroblast growth factor receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0071773//cellular response to BMP stimulus;GO:0032332//positive regulation of chondrocyte differentiation;GO:0030217//T cell differentiation;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0042487//regulation of odontogenesis of dentin-containing tooth;GO:0045879//negative regulation of smoothened signaling pathway;GO:0030509//BMP signaling pathway;GO:0010467//gene expression",GO:0070491//repressing transcription factor binding;GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0043425//bHLH transcription factor binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044212//transcription regulatory region DNA binding,K09278//Transcriptional misregulation in cancer
8600,0,0,0,0,0,0,0,67,28,0,0,0,"TNFSF11;tumor necrosis factor (ligand) superfamily, member 11",GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0055074//calcium ion homeostasis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002158//osteoclast proliferation;GO:0034112//positive regulation of homotypic cell-cell adhesion;GO:0007257//activation of JUN kinase activity;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030316//osteoclast differentiation;GO:0045780//positive regulation of bone resorption;GO:0070371//ERK1 and ERK2 cascade;GO:1902533//positive regulation of intracellular signal transduction;GO:2001206//positive regulation of osteoclast development;GO:0002548//monocyte chemotaxis;GO:0071812//positive regulation of fever generation by positive regulation of prostaglandin secretion;GO:0045453//bone resorption;GO:0019221//cytokine-mediated signaling pathway;GO:0050870//positive regulation of T cell activation;GO:0051466//positive regulation of corticotropin-releasing hormone secretion;GO:0051897//positive regulation of protein kinase B signaling;GO:0001503//ossification;GO:0051260//protein homooligomerization;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0043406//positive regulation of MAP kinase activity;GO:0006955//immune response;GO:0033598//mammary gland epithelial cell proliferation;GO:0060749//mammary gland alveolus development;GO:0071848//positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling;GO:0045672//positive regulation of osteoclast differentiation;GO:0009887//organ morphogenesis;GO:0046330//positive regulation of JNK cascade,GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding,K05473//Osteoclast differentiation;Cytokine-cytokine receptor interaction;Rheumatoid arthritis;NF-kappa B signaling pathway
8601,0,0,0,0,0,0,0,0,23,0,0,0,RGS20;regulator of G-protein signaling 20,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity;GO:0005515//protein binding,K07524//Axon guidance
8602,13,0,53,71,157,13,0,0,9,0,119,0,NOP14;NOP14 nucleolar protein,GO:0030686//90S preribosome;GO:0005634//nucleus;GO:0032040//small-subunit processome;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0030692//Noc4p-Nop14p complex,"GO:0000462//maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364//rRNA processing;GO:0000480//endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000447//endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274//ribosomal small subunit biogenesis;GO:0000472//endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)",GO:0019899//enzyme binding;GO:0044822//poly(A) RNA binding;GO:0030515//snoRNA binding,-
8603,114,0,0,1,2,64,0,11,5,7,11,0,"FAM193A;family with sequence similarity 193, member A",-,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K01875//Arginine and proline metabolism;Biotin metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
8604,0,0,0,0,17,12,0,0,7,0,0,0,"SLC25A12;solute carrier family 25 (aspartate/glutamate carrier), member 12",GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0015813//L-glutamate transport;GO:0006006//glucose metabolic process;GO:0044281//small molecule metabolic process;GO:0043490//malate-aspartate shuttle;GO:0006094//gluconeogenesis;GO:0055085//transmembrane transport;GO:0051592//response to calcium ion;GO:0015810//aspartate transport,GO:0005509//calcium ion binding;GO:0015183//L-aspartate transmembrane transporter activity;GO:0005313//L-glutamate transmembrane transporter activity,-
8605,0,0,0,8,30,0,74,0,1,0,16,0,"PLA2G4C;phospholipase A2, group IVC (cytosolic, calcium-independent)",GO:0005938//cell cortex;GO:0005635//nuclear envelope;GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0005829//cytosol,GO:0036151//phosphatidylcholine acyl-chain remodeling;GO:0019369//arachidonic acid metabolic process;GO:0046475//glycerophospholipid catabolic process;GO:0035556//intracellular signal transduction;GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response;GO:0046474//glycerophospholipid biosynthetic process;GO:0036149//phosphatidylinositol acyl-chain remodeling;GO:0044281//small molecule metabolic process;GO:0007567//parturition;GO:0036152//phosphatidylethanolamine acyl-chain remodeling,GO:0047499//calcium-independent phospholipase A2 activity;GO:0005543//phospholipid binding,K01047//MAPK signaling pathway;Linoleic acid metabolism;Glutamatergic synapse;Vascular smooth muscle contraction;Metabolic pathways;Pancreatic secretion;Serotonergic synapse;alpha-Linolenic acid metabolism;GnRH signaling pathway;Glycerophospholipid metabolism;VEGF signaling pathway;Ether lipid metabolism;Arachidonic acid metabolism;Toxoplasmosis;Fat digestion and absorption;Fc gamma R-mediated phagocytosis;Fc epsilon RI signaling pathway;Long-term depression
8607,0,16,0,2,21,0,18,0,29,119,0,0,RUVBL1;RuvB-like AAA ATPase 1,GO:0016363//nuclear matrix;GO:0000812//Swr1 complex;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0035267//NuA4 histone acetyltransferase complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0071339//MLL1 complex;GO:0005654//nucleoplasm;GO:0031011//Ino80 complex;GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome,"GO:0006351//transcription, DNA-templated;GO:0040008//regulation of growth;GO:0043968//histone H2A acetylation;GO:0007283//spermatogenesis;GO:0006325//chromatin organization;GO:0032508//DNA duplex unwinding;GO:0006334//nucleosome assembly;GO:0043967//histone H4 acetylation;GO:0006281//DNA repair;GO:0007067//mitotic nuclear division;GO:0006310//DNA recombination;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0034080//CENP-A containing nucleosome assembly",GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0003678//DNA helicase activity;GO:0005524//ATP binding,K04499//Wnt signaling pathway
8608,0,0,0,0,0,4,0,0,10,0,6,0,RDH16;retinol dehydrogenase 16 (all-trans),GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0055114//oxidation-reduction process;GO:0006629//lipid metabolic process,GO:0009055//electron carrier activity;GO:0004745//retinol dehydrogenase activity,K11154//Retinol metabolism;Metabolic pathways
8609,53,1,0,8,3,18,4,1,29,0,5,0,KLF7;Kruppel-like factor 7 (ubiquitous),GO:0005634//nucleus,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0048813//dendrite morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
861,21,0,1,21,1,60,0,1,32,0,21,0,RUNX1;runt-related transcription factor 1,GO:0005634//nucleus;GO:0005604//basement membrane,"GO:0001889//liver development;GO:0031069//hair follicle morphogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030854//positive regulation of granulocyte differentiation;GO:0045766//positive regulation of angiogenesis;GO:0001701//in utero embryonic development;GO:0030853//negative regulation of granulocyte differentiation;GO:0007417//central nervous system development;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0048266//behavioral response to pain;GO:2000872//positive regulation of progesterone secretion;GO:0006351//transcription, DNA-templated;GO:0048935//peripheral nervous system neuron development;GO:0030099//myeloid cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060216//definitive hemopoiesis;GO:0071336//regulation of hair follicle cell proliferation;GO:0002318//myeloid progenitor cell differentiation;GO:0030097//hemopoiesis;GO:0001501//skeletal system development;GO:0035162//embryonic hemopoiesis;GO:0009966//regulation of signal transduction;GO:0071425//hematopoietic stem cell proliferation",GO:0005524//ATP binding;GO:0003677//DNA binding;GO:0070491//repressing transcription factor binding;GO:0000975//regulatory region DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0005509//calcium ion binding,K08367//Acute myeloid leukemia;Chronic myeloid leukemia;Pathways in cancer;Transcriptional misregulation in cancer
8611,0,31,34,121,352,11,0,0,23,0,61,563,PPAP2A;phosphatidic acid phosphatase type 2A,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0019216//regulation of lipid metabolic process;GO:0008285//negative regulation of cell proliferation;GO:0006665//sphingolipid metabolic process;GO:0006470//protein dephosphorylation;GO:0030148//sphingolipid biosynthetic process;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0008354//germ cell migration;GO:0046839//phospholipid dephosphorylation;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0030521//androgen receptor signaling pathway,GO:0008195//phosphatidate phosphatase activity,K01080//Glycerolipid metabolism;Fat digestion and absorption;Metabolic pathways;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Sphingolipid metabolism;Ether lipid metabolism
8612,0,0,0,0,0,0,0,0,18,0,0,0,PPAP2C;phosphatidic acid phosphatase type 2C,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0016311//dephosphorylation;GO:0006665//sphingolipid metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process,GO:0008195//phosphatidate phosphatase activity;GO:0004721//phosphoprotein phosphatase activity,K01080//Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Sphingolipid metabolism;Ether lipid metabolism;Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption
8613,0,0,0,1,10,0,0,12,30,0,0,0,PPAP2B;phosphatidic acid phosphatase type 2B,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005912//adherens junction,GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0001568//blood vessel development;GO:0030111//regulation of Wnt signaling pathway;GO:0006629//lipid metabolic process;GO:0044328//canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration;GO:0050821//protein stabilization;GO:0001933//negative regulation of protein phosphorylation;GO:0044330//canonical Wnt signaling pathway involved in positive regulation of wound healing;GO:0016311//dephosphorylation;GO:0034109//homotypic cell-cell adhesion;GO:0008354//germ cell migration;GO:0001702//gastrulation with mouth forming second;GO:0060020//Bergmann glial cell differentiation;GO:0006644//phospholipid metabolic process;GO:0044329//canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0006665//sphingolipid metabolic process,GO:0042577//lipid phosphatase activity;GO:0008195//phosphatidate phosphatase activity;GO:0005515//protein binding;GO:0042392//sphingosine-1-phosphate phosphatase activity;GO:0005178//integrin binding;GO:0004721//phosphoprotein phosphatase activity,K01080//Ether lipid metabolism;Sphingolipid metabolism;Glycerophospholipid metabolism;Fc gamma R-mediated phagocytosis;Fat digestion and absorption;Metabolic pathways;Glycerolipid metabolism
8614,170,0,0,0,0,18,0,0,8,0,27,0,STC2;stanniocalcin 2,GO:0048471//perinuclear region of cytoplasm;GO:0005615//extracellular space;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus,GO:0007566//embryo implantation;GO:0006979//response to oxidative stress;GO:0046697//decidualization;GO:0043434//response to peptide hormone;GO:0006874//cellular calcium ion homeostasis;GO:0040015//negative regulation of multicellular organism growth;GO:0010629//negative regulation of gene expression;GO:2001256//regulation of store-operated calcium entry;GO:0046885//regulation of hormone biosynthetic process;GO:0033280//response to vitamin D;GO:0071456//cellular response to hypoxia;GO:0030968//endoplasmic reticulum unfolded protein response,GO:0019899//enzyme binding;GO:0020037//heme binding;GO:0042803//protein homodimerization activity;GO:0005179//hormone activity,-
8615,0,44,1,34,68,3,50,0,41,0,17,0,USO1;USO1 vesicle transport factor,GO:0012507//ER to Golgi transport vesicle membrane;GO:0005829//cytosol;GO:0005795//Golgi stack;GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0006886//intracellular protein transport;GO:0048211//Golgi vesicle docking;GO:0000278//mitotic cell cycle;GO:0048280//vesicle fusion with Golgi apparatus;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0045056//transcytosis;GO:0061025//membrane fusion,GO:0044822//poly(A) RNA binding;GO:0008565//protein transporter activity,K16072//NF-kappa B signaling pathway;K10381//Arrhythmogenic right ventricular cardiomyopathy (ARVC)
8618,182,47,3,0,10,23,0,62,15,7,0,0,CADPS;Ca++-dependent secretion activator,GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse,GO:0015031//protein transport;GO:0016082//synaptic vesicle priming;GO:0050432//catecholamine secretion;GO:0016050//vesicle organization;GO:0006887//exocytosis,GO:0008289//lipid binding;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
862,109,0,0,0,0,27,0,26,38,14,5,57,"RUNX1T1;runt-related transcription factor 1; translocated to, 1 (cyclin D-related)",GO:0016363//nuclear matrix,"GO:0006091//generation of precursor metabolites and energy;GO:0051101//regulation of DNA binding;GO:0045444//fat cell differentiation;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K10053//Transcriptional misregulation in cancer;Pathways in cancer;Acute myeloid leukemia
8620,0,0,0,0,0,0,11,0,12,0,0,0,NPFF;neuropeptide FF-amide peptide precursor,GO:0005576//extracellular region;GO:0030425//dendrite;GO:0043204//perikaryon;GO:0005615//extracellular space;GO:0043679//axon terminus;GO:0031982//vesicle,GO:0010459//negative regulation of heart rate;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0021510//spinal cord development;GO:0042493//response to drug;GO:0045777//positive regulation of blood pressure;GO:0007218//neuropeptide signaling pathway;GO:0060079//regulation of excitatory postsynaptic membrane potential;GO:0032099//negative regulation of appetite;GO:0002438//acute inflammatory response to antigenic stimulus;GO:0070253//somatostatin secretion;GO:0043278//response to morphine;GO:0030103//vasopressin secretion;GO:0007268//synaptic transmission;GO:0046676//negative regulation of insulin secretion;GO:0003254//regulation of membrane depolarization;GO:0051930//regulation of sensory perception of pain;GO:0060135//maternal process involved in female pregnancy,GO:0005184//neuropeptide hormone activity;GO:0005102//receptor binding;GO:0001664//G-protein coupled receptor binding,-
8621,0,39,1,19,118,0,23,122,101,0,8,0,CDK13;cyclin-dependent kinase 13,GO:0019908//nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0016607//nuclear speck;GO:0005615//extracellular space;GO:0002945//cyclin K-CDK13 complex,"GO:0070816//phosphorylation of RNA polymerase II C-terminal domain;GO:0007088//regulation of mitosis;GO:0007275//multicellular organismal development;GO:0030097//hemopoiesis;GO:0016032//viral process;GO:0008284//positive regulation of cell proliferation;GO:0000380//alternative mRNA splicing, via spliceosome",GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0030332//cyclin binding,-
8622,0,10,0,20,146,20,51,0,70,0,10,0,PDE8B;phosphodiesterase 8B,GO:0005829//cytosol,GO:0000160//phosphorelay signal transduction system;GO:0046676//negative regulation of insulin secretion;GO:0006198//cAMP catabolic process;GO:0009187//cyclic nucleotide metabolic process,"GO:0004871//signal transducer activity;GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0004115//3',5'-cyclic-AMP phosphodiesterase activity",K01120//Purine metabolism;Morphine addiction
8623,0,0,0,0,36,0,0,3,2,0,1,0,ASMTL;acetylserotonin O-methyltransferase-like,GO:0005737//cytoplasm,GO:0032259//methylation,GO:0008171//O-methyltransferase activity,K00543//Tryptophan metabolism;Metabolic pathways
8624,0,0,0,10,1,0,0,0,0,0,0,0,"PSMG1;proteasome (prosome, macropain) assembly chaperone 1",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:0043248//proteasome assembly;GO:0021930//cerebellar granule cell precursor proliferation,GO:0070628//proteasome binding;GO:0005515//protein binding,-
8625,0,131,0,139,85,5,0,376,51,1,128,0,RFXANK;regulatory factor X-associated ankyrin-containing protein,GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007265//Ras protein signal transduction;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042826//histone deacetylase binding;GO:0003712//transcription cofactor activity,K08062//Tuberculosis;Antigen processing and presentation;Primary immunodeficiency
8626,181,0,0,0,0,0,0,0,72,6,4,0,TP63;tumor protein p63,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0030425//dendrite;GO:0005667//transcription factor complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0045747//positive regulation of Notch signaling pathway;GO:0061436//establishment of skin barrier;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007569//cell aging;GO:0030216//keratinocyte differentiation;GO:0010165//response to X-ray;GO:0060197//cloacal septation;GO:0007219//Notch signaling pathway;GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2000381//negative regulation of mesoderm development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0051402//neuron apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0031571//mitotic G1 DNA damage checkpoint;GO:0034644//cellular response to UV;GO:0043616//keratinocyte proliferation;GO:0048807//female genitalia morphogenesis;GO:0048745//smooth muscle tissue development;GO:0010332//response to gamma radiation;GO:0060157//urinary bladder development;GO:1902808//positive regulation of cell cycle G1/S phase transition;GO:0045669//positive regulation of osteoblast differentiation;GO:0051289//protein homotetramerization;GO:0042771//intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0031069//hair follicle morphogenesis;GO:0048485//sympathetic nervous system development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060529//squamous basal epithelial stem cell differentiation involved in prostate gland acinus development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0045617//negative regulation of keratinocyte differentiation;GO:0001501//skeletal system development;GO:0006338//chromatin remodeling;GO:0060513//prostatic bud formation;GO:0007499//ectoderm and mesoderm interaction;GO:0002064//epithelial cell development;GO:0010838//positive regulation of keratinocyte proliferation;GO:0006978//DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;GO:0010259//multicellular organismal aging;GO:0030859//polarized epithelial cell differentiation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0009954//proximal/distal pattern formation;GO:0043066//negative regulation of apoptotic process;GO:0001736//establishment of planar polarity;GO:0006351//transcription, DNA-templated;GO:2000271//positive regulation of fibroblast apoptotic process;GO:2000773//negative regulation of cellular senescence;GO:0036342//post-anal tail morphogenesis;GO:0010482//regulation of epidermal cell division;GO:0030326//embryonic limb morphogenesis",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0050699//WW domain binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0044212//transcription regulatory region DNA binding;GO:0003690//double-stranded DNA binding;GO:0003684//damaged DNA binding;GO:0042802//identical protein binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0000989//transcription factor binding transcription factor activity,-
8629,0,0,0,0,0,0,0,0,50,0,0,0,JRK;Jrk homolog (mouse),GO:0005634//nucleus,-,GO:0005515//protein binding;GO:0003677//DNA binding,-
863,98,0,0,0,0,9,0,7,40,0,0,5,"CBFA2T3;core-binding factor, runt domain, alpha subunit 2; translocated to, 3",GO:0005730//nucleolus;GO:0000139//Golgi membrane;GO:0005654//nucleoplasm,"GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008283//cell proliferation;GO:0030851//granulocyte differentiation",GO:0003682//chromatin binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K10053//Pathways in cancer;Acute myeloid leukemia;Transcriptional misregulation in cancer
8630,0,0,0,5,0,0,0,0,18,0,0,0,HSD17B6;hydroxysteroid (17-beta) dehydrogenase 6,GO:0005622//intracellular;GO:0005783//endoplasmic reticulum;GO:0031901//early endosome membrane,GO:0055114//oxidation-reduction process;GO:0006702//androgen biosynthetic process;GO:0006710//androgen catabolic process,GO:0004745//retinol dehydrogenase activity;GO:0004303//estradiol 17-beta-dehydrogenase activity;GO:0003824//catalytic activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0009055//electron carrier activity;GO:0016491//oxidoreductase activity,K13369//Retinol metabolism;Steroid hormone biosynthesis;Metabolic pathways
8631,0,0,0,0,0,38,8,0,0,0,0,0,SKAP1;src kinase associated phosphoprotein 1,GO:0005886//plasma membrane;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005634//nucleus,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0009967//positive regulation of signal transduction;GO:0050852//T cell receptor signaling pathway",GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0019903//protein phosphatase binding;GO:0032403//protein complex binding;GO:0042169//SH2 domain binding;GO:0005070//SH3/SH2 adaptor activity,K12326//MAPK signaling pathway;K13738//Bacterial invasion of epithelial cells;K07984//Natural killer cell mediated cytotoxicity;K04349//MAPK signaling pathway;Focal adhesion;K12559//Fc gamma R-mediated phagocytosis
8632,46,84,16,28,6,54,87,77,148,303,181,171,"DNAH17;dynein, axonemal, heavy chain 17",GO:0005874//microtubule;GO:0005858//axonemal dynein complex,GO:0006200//ATP catabolic process;GO:0008152//metabolic process;GO:0001539//cilium or flagellum-dependent cell motility;GO:0007018//microtubule-based movement,GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0005524//ATP binding,K10408//Huntington's disease
8633,0,0,0,0,0,6,64,21,44,0,1,0,UNC5C;unc-5 homolog C (C. elegans),GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007411//axon guidance;GO:0030334//regulation of cell migration;GO:0043065//positive regulation of apoptotic process;GO:0038007//netrin-activated signaling pathway;GO:0007420//brain development;GO:0006915//apoptotic process;GO:0033564//anterior/posterior axon guidance,GO:0005042//netrin receptor activity,K07521//Axon guidance
8634,0,4,0,32,52,0,51,0,10,0,2,0,RTCA;RNA 3'-terminal phosphate cyclase,GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0006396//RNA processing,GO:0044822//poly(A) RNA binding;GO:0003963//RNA-3'-phosphate cyclase activity;GO:0003723//RNA binding;GO:0005524//ATP binding,-
8635,0,0,0,0,0,0,0,0,12,0,0,0,RNASET2;ribonuclease T2,GO:0005788//endoplasmic reticulum lumen;GO:0043202//lysosomal lumen;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space,"GO:0090501//RNA phosphodiester bond hydrolysis;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006401//RNA catabolic process",GO:0003723//RNA binding;GO:0033897//ribonuclease T2 activity;GO:0004540//ribonuclease activity,-
8636,0,0,0,22,0,0,0,112,0,0,1,0,SSNA1;Sjogren syndrome nuclear autoantigen 1,GO:0005829//cytosol;GO:0036064//ciliary basal body;GO:0005634//nucleus;GO:0005813//centrosome,GO:0042073//intraciliary transport;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0060830//ciliary receptor clustering involved in smoothened signaling pathway,GO:0042802//identical protein binding,-
8637,0,0,0,0,20,0,0,0,0,0,0,0,EIF4EBP3;eukaryotic translation initiation factor 4E binding protein 3,GO:0016020//membrane;GO:0016281//eukaryotic translation initiation factor 4F complex,GO:0045947//negative regulation of translational initiation,GO:0030371//translation repressor activity;GO:0005515//protein binding;GO:0008190//eukaryotic initiation factor 4E binding,K07205//RNA transport;ErbB signaling pathway;Acute myeloid leukemia;Insulin signaling pathway;mTOR signaling pathway
8638,0,0,0,0,0,0,0,0,24,0,0,0,OASL;2'-5'-oligoadenylate synthetase-like,GO:0005829//cytosol;GO:0016020//membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0019221//cytokine-mediated signaling pathway;GO:0009615//response to virus;GO:0008152//metabolic process;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0045071//negative regulation of viral genome replication;GO:0051607//defense response to virus;GO:0060337//type I interferon signaling pathway,GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0046966//thyroid hormone receptor binding;GO:0005524//ATP binding;GO:0001730//2'-5'-oligoadenylate synthetase activity,-
8639,0,36,0,0,0,0,27,16,13,55,4,0,"AOC3;amine oxidase, copper containing 3",GO:0005737//cytoplasm;GO:0005902//microvillus;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface,GO:0055114//oxidation-reduction process;GO:0006812//cation transport;GO:0006954//inflammatory response;GO:0046677//response to antibiotic;GO:0007155//cell adhesion;GO:0009308//amine metabolic process,GO:0052593//tryptamine:oxygen oxidoreductase (deaminating) activity;GO:0052595//aliphatic-amine oxidase activity;GO:0052594//aminoacetone:oxygen oxidoreductase(deaminating) activity;GO:0052596//phenethylamine:oxygen oxidoreductase (deaminating) activity;GO:0005507//copper ion binding;GO:0005261//cation channel activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008131//primary amine oxidase activity;GO:0005515//protein binding;GO:0048038//quinone binding;GO:0005509//calcium ion binding,"K00276//Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Isoquinoline alkaloid biosynthesis;Phenylalanine metabolism;Metabolic pathways;beta-Alanine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;Tyrosine metabolism"
864,0,0,0,0,0,0,0,60,5,0,0,287,RUNX3;runt-related transcription factor 3,GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0048469//cell maturation;GO:0045786//negative regulation of cell cycle;GO:0031069//hair follicle morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0050680//negative regulation of epithelial cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0048935//peripheral nervous system neuron development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002062//chondrocyte differentiation;GO:0006468//protein phosphorylation;GO:0007411//axon guidance;GO:0032609//interferon-gamma production",GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005524//ATP binding;GO:0000981//sequence-specific DNA binding RNA polymerase II transcription factor activity,-
8642,0,0,0,0,0,4,53,66,71,0,46,0,DCHS1;dachsous cadherin-related 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0045177//apical part of cell,GO:0035329//hippo signaling;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0090102//cochlea development;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0021915//neural tube development;GO:0043931//ossification involved in bone maturation;GO:0022008//neurogenesis;GO:0001658//branching involved in ureteric bud morphogenesis;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0003007//heart morphogenesis;GO:0036342//post-anal tail morphogenesis;GO:0048565//digestive tract development,GO:0005509//calcium ion binding,-
8643,14,0,0,0,0,21,0,7,8,0,3,0,PTCH2;patched 2,GO:0016021//integral component of membrane,GO:0008544//epidermis development;GO:0042633//hair cycle;GO:0007165//signal transduction;GO:0045879//negative regulation of smoothened signaling pathway,GO:0008158//hedgehog receptor activity;GO:0005119//smoothened binding;GO:0097108//hedgehog family protein binding,K11101//Pathways in cancer;Hedgehog signaling pathway;Basal cell carcinoma
8644,0,0,0,0,0,0,0,0,5,0,7,0,"AKR1C3;aldo-keto reductase family 1, member C3",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005622//intracellular;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,"GO:0071276//cellular response to cadmium ion;GO:0007603//phototransduction, visible light;GO:0008202//steroid metabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0001523//retinoid metabolic process;GO:0071395//cellular response to jasmonic acid stimulus;GO:0071277//cellular response to calcium ion;GO:0006693//prostaglandin metabolic process;GO:0044281//small molecule metabolic process;GO:0034614//cellular response to reactive oxygen species;GO:0019371//cyclooxygenase pathway;GO:0044598//doxorubicin metabolic process;GO:0007584//response to nutrient;GO:0055114//oxidation-reduction process;GO:0042448//progesterone metabolic process;GO:0016488//farnesol catabolic process;GO:0030216//keratinocyte differentiation;GO:0061370//testosterone biosynthetic process;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0034694//response to prostaglandin;GO:0000060//protein import into nucleus, translocation;GO:0044597//daunorubicin metabolic process;GO:0010942//positive regulation of cell death;GO:0044259//multicellular organismal macromolecule metabolic process;GO:0048385//regulation of retinoic acid receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:1900053//negative regulation of retinoic acid biosynthetic process;GO:0051897//positive regulation of protein kinase B signaling;GO:2000224//regulation of testosterone biosynthetic process;GO:0071384//cellular response to corticosteroid stimulus;GO:0019369//arachidonic acid metabolic process;GO:0008584//male gonad development;GO:0042574//retinal metabolic process;GO:0071379//cellular response to prostaglandin stimulus;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0070293//renal absorption;GO:0009267//cellular response to starvation","GO:0004958//prostaglandin F receptor activity;GO:0047045//testosterone 17-beta-dehydrogenase (NADP+) activity;GO:0047020//15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0036131//prostaglandin D2 11-ketoreductase activity;GO:0004033//aldo-keto reductase (NADP) activity;GO:0047035//testosterone dehydrogenase (NAD+) activity;GO:0018636//phenanthrene 9,10-monooxygenase activity;GO:0001758//retinal dehydrogenase activity;GO:0047115//trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047023//androsterone dehydrogenase activity;GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0004032//alditol:NADP+ 1-oxidoreductase activity;GO:0047718//indanol dehydrogenase activity;GO:0035410//dihydrotestosterone 17-beta-dehydrogenase activity;GO:0045703//ketoreductase activity;GO:0045550//geranylgeranyl reductase activity;GO:0047017//prostaglandin-F synthase activity;GO:0047787//delta4-3-oxosteroid 5beta-reductase activity;GO:0047086//ketosteroid monooxygenase activity;GO:0004745//retinol dehydrogenase activity","K00212//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Arachidonic acid metabolism;Primary bile acid biosynthesis;Metabolic pathways;K00100//Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Methane metabolism;Butanoate metabolism;Microbial metabolism in diverse environments;Bisphenol degradation;Benzoate degradation;Limonene and pinene degradation;Chloroalkane and chloroalkene degradation;Metabolic pathways;Linoleic acid metabolism;Two-component system;Naphthalene degradation;Fructose and mannose metabolism;K00092//Primary bile acid biosynthesis;Metabolic pathways;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K00089//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Arachidonic acid metabolism;Primary bile acid biosynthesis;Metabolic pathways;K00037//Metabolic pathways;Primary bile acid biosynthesis;Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;K05295//Steroid hormone biosynthesis;K04119//Metabolism of xenobiotics by cytochrome P450;Steroid hormone biosynthesis;Arachidonic acid metabolism"
8645,0,0,0,0,0,17,3,0,12,0,6,0,"KCNK5;potassium channel, subfamily K, member 5",GO:0005887//integral component of plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007588//excretion;GO:0006813//potassium ion transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,K04916//Protein digestion and absorption
8646,96,0,0,0,0,16,8,17,79,0,0,1,CHRD;chordin,GO:0005615//extracellular space,GO:0030514//negative regulation of BMP signaling pathway;GO:0045785//positive regulation of cell adhesion;GO:0001702//gastrulation with mouth forming second;GO:0001649//osteoblast differentiation;GO:0001707//mesoderm formation;GO:0033504//floor plate development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0030900//forebrain development;GO:0030336//negative regulation of cell migration;GO:0021919//BMP signaling pathway involved in spinal cord dorsal/ventral patterning;GO:0045668//negative regulation of osteoblast differentiation;GO:0001501//skeletal system development,GO:0045545//syndecan binding;GO:0005515//protein binding;GO:0008201//heparin binding;GO:0019955//cytokine binding,K04657//TGF-beta signaling pathway
8647,42,0,0,0,0,7,21,91,72,0,5,0,"ABCB11;ATP-binding cassette, sub-family B (MDR/TAP), member 11",GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0046581//intercellular canaliculus;GO:0016021//integral component of membrane,GO:0015721//bile acid and bile salt transport;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0015722//canalicular bile acid transport;GO:0035725//sodium ion transmembrane transport;GO:0008206//bile acid metabolic process;GO:0006699//bile acid biosynthetic process;GO:0055085//transmembrane transport;GO:0006810//transport,"GO:0015126//canalicular bile acid transmembrane transporter activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0008554//sodium-exporting ATPase activity, phosphorylative mechanism;GO:0015432//bile acid-exporting ATPase activity;GO:0005524//ATP binding;GO:0005215//transporter activity",K05664//Bile secretion;ABC transporters
8648,0,5,0,0,61,21,1,0,31,0,0,0,NCOA1;nuclear receptor coactivator 1,GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005737//cytoplasm;GO:0043005//neuron projection,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0044255//cellular lipid metabolic process;GO:0021549//cerebellum development;GO:0060179//male mating behavior;GO:0044281//small molecule metabolic process;GO:0021766//hippocampus development;GO:0045925//positive regulation of female receptivity;GO:0021854//hypothalamus development;GO:0006351//transcription, DNA-templated;GO:0000435//positive regulation of transcription from RNA polymerase II promoter by galactose;GO:0060206//estrous cycle phase;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042698//ovulation cycle;GO:0032870//cellular response to hormone stimulus;GO:0007595//lactation;GO:0043967//histone H4 acetylation;GO:0032526//response to retinoic acid;GO:0032570//response to progesterone;GO:0045666//positive regulation of neuron differentiation;GO:0032355//response to estradiol;GO:0021987//cerebral cortex development;GO:2001038//regulation of cellular response to drug;GO:0060713//labyrinthine layer morphogenesis;GO:0008584//male gonad development;GO:0043065//positive regulation of apoptotic process",GO:0032403//protein complex binding;GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0050681//androgen receptor binding;GO:0046965//retinoid X receptor binding;GO:0005515//protein binding;GO:0001012//RNA polymerase II regulatory region DNA binding;GO:0033142//progesterone receptor binding;GO:0003682//chromatin binding;GO:0046983//protein dimerization activity;GO:0019899//enzyme binding;GO:0047485//protein N-terminus binding;GO:0030331//estrogen receptor binding;GO:0004402//histone acetyltransferase activity;GO:0004871//signal transducer activity;GO:0001105//RNA polymerase II transcription coactivator activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,-
8649,0,30,0,49,48,25,0,0,51,0,0,0,"LAMTOR3;late endosomal/lysosomal adaptor, MAPK and MTOR activator 3",GO:0070062//extracellular vesicular exosome;GO:0005925//focal adhesion;GO:0071986//Ragulator complex,GO:0032008//positive regulation of TOR signaling;GO:0043547//positive regulation of GTPase activity;GO:0034613//cellular protein localization;GO:0071230//cellular response to amino acid stimulus,GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032947//protein complex scaffold,K04370//MAPK signaling pathway
865,82,0,0,0,8,7,0,0,31,0,0,0,"CBFB;core-binding factor, beta subunit",GO:0016020//membrane;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0001649//osteoblast differentiation;GO:0030098//lymphocyte differentiation;GO:0060216//definitive hemopoiesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048469//cell maturation;GO:0030099//myeloid cell differentiation,GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0003713//transcription coactivator activity,-
8650,0,21,0,9,57,0,0,0,30,35,0,0,NUMB;numb homolog (Drosophila),GO:0005634//nucleus;GO:0019897//extrinsic component of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005925//focal adhesion;GO:0016323//basolateral plasma membrane;GO:0045177//apical part of cell;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0030136//clathrin-coated vesicle,GO:0045746//negative regulation of Notch signaling pathway;GO:0030335//positive regulation of cell migration;GO:0007411//axon guidance;GO:0060487//lung epithelial cell differentiation;GO:0021670//lateral ventricle development;GO:0021849//neuroblast division in subventricular zone;GO:0007219//Notch signaling pathway;GO:0034332//adherens junction organization;GO:0050769//positive regulation of neurogenesis;GO:0030862//positive regulation of polarized epithelial cell differentiation,GO:0045296//cadherin binding;GO:0005515//protein binding;GO:0045294//alpha-catenin binding;GO:0008013//beta-catenin binding,K06057//Notch signaling pathway
8651,0,0,0,0,0,8,0,0,14,0,0,0,SOCS1;suppressor of cytokine signaling 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0040008//regulation of growth;GO:0001932//regulation of protein phosphorylation;GO:0016567//protein ubiquitination;GO:0071230//cellular response to amino acid stimulus;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0042518//negative regulation of tyrosine phosphorylation of Stat3 protein;GO:0006469//negative regulation of protein kinase activity;GO:0046426//negative regulation of JAK-STAT cascade;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0045444//fat cell differentiation;GO:0007259//JAK-STAT cascade,GO:0005159//insulin-like growth factor receptor binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0004860//protein kinase inhibitor activity;GO:0019210//kinase inhibitor activity,K04694//Ubiquitin mediated proteolysis;Type II diabetes mellitus;Insulin signaling pathway;Jak-STAT signaling pathway;Toxoplasmosis;Osteoclast differentiation
8653,0,34,0,15,120,0,0,0,0,0,0,0,"DDX3Y;DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked",GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006200//ATP catabolic process,GO:0003723//RNA binding;GO:0005524//ATP binding;GO:0008026//ATP-dependent helicase activity;GO:0003677//DNA binding,K11594//RIG-I-like receptor signaling pathway
8654,0,31,109,59,49,34,45,123,38,6,42,0,"PDE5A;phosphodiesterase 5A, cGMP-specific",GO:0005829//cytosol,GO:0010613//positive regulation of cardiac muscle hypertrophy;GO:0007596//blood coagulation;GO:0042130//negative regulation of T cell proliferation;GO:0055119//relaxation of cardiac muscle;GO:0060282//positive regulation of oocyte development;GO:0055118//negative regulation of cardiac muscle contraction;GO:0007165//signal transduction;GO:0043406//positive regulation of MAP kinase activity;GO:0046069//cGMP catabolic process,"GO:0030553//cGMP binding;GO:0046872//metal ion binding;GO:0004114//3',5'-cyclic-nucleotide phosphodiesterase activity;GO:0047555//3',5'-cyclic-GMP phosphodiesterase activity",K13762//Purine metabolism
8655,0,56,0,0,19,0,0,0,0,0,0,0,"DYNLL1;dynein, light chain, LC8-type 1",GO:0016020//membrane;GO:0072686//mitotic spindle;GO:0005868//cytoplasmic dynein complex;GO:0000776//kinetochore;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005739//mitochondrion;GO:0008180//COP9 signalosome;GO:0005874//microtubule;GO:0005634//nucleus,"GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0030036//actin cytoskeleton organization;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0097193//intrinsic apoptotic signaling pathway;GO:0007292//female gamete generation;GO:0016032//viral process;GO:0021762//substantia nigra development;GO:0050790//regulation of catalytic activity;GO:0006915//apoptotic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0042326//negative regulation of phosphorylation;GO:0006810//transport;GO:0007017//microtubule-based process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle",GO:0003774//motor activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008022//protein C-terminus binding;GO:0030235//nitric-oxide synthase regulator activity;GO:0019904//protein domain specific binding;GO:0019899//enzyme binding,K10418//Vasopressin-regulated water reabsorption
8658,3,40,49,58,227,0,36,2,40,146,12,0,"TNKS;tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase","GO:0000781//chromosome, telomeric region;GO:0031965//nuclear membrane;GO:0005794//Golgi apparatus;GO:0000784//nuclear chromosome, telomeric region;GO:0000139//Golgi membrane;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005643//nuclear pore;GO:0000922//spindle pole;GO:0000242//pericentriolar material;GO:0005730//nucleolus;GO:0005829//cytosol","GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070198//protein localization to chromosome, telomeric region;GO:0043392//negative regulation of DNA binding;GO:0051225//spindle assembly;GO:0018105//peptidyl-serine phosphorylation;GO:0032212//positive regulation of telomere maintenance via telomerase;GO:0007067//mitotic nuclear division;GO:0016055//Wnt signaling pathway;GO:0070213//protein auto-ADP-ribosylation;GO:0007052//mitotic spindle organization;GO:0018107//peptidyl-threonine phosphorylation;GO:0051028//mRNA transport;GO:0006471//protein ADP-ribosylation;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0000209//protein polyubiquitination;GO:0070212//protein poly-ADP-ribosylation;GO:0015031//protein transport",GO:0003950//NAD+ ADP-ribosyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
8659,0,26,0,22,4,33,0,1,4,0,0,0,"ALDH4A1;aldehyde dehydrogenase 4 family, member A1",GO:0005759//mitochondrial matrix,GO:0044281//small molecule metabolic process;GO:0006561//proline biosynthetic process;GO:0010133//proline catabolic process to glutamate;GO:0006537//glutamate biosynthetic process;GO:0006562//proline catabolic process;GO:0019470//4-hydroxyproline catabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0055114//oxidation-reduction process,GO:0003842//1-pyrroline-5-carboxylate dehydrogenase activity;GO:0009055//electron carrier activity;GO:0042802//identical protein binding;GO:0004029//aldehyde dehydrogenase (NAD) activity,"K00294//Alanine, aspartate and glutamate metabolism;Metabolic pathways;Arginine and proline metabolism"
866,0,0,0,0,5,0,0,0,26,141,0,0,"SERPINA6;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0008211//glucocorticoid metabolic process;GO:0010951//negative regulation of endopeptidase activity;GO:0006810//transport;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005496//steroid binding,K03984//Complement and coagulation cascades
8660,28,21,1,5,20,0,0,1,22,0,10,0,IRS2;insulin receptor substrate 2,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0071333//cellular response to glucose stimulus;GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0030879//mammary gland development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0006006//glucose metabolic process;GO:0032000//positive regulation of fatty acid beta-oxidation;GO:0007165//signal transduction;GO:0002903//negative regulation of B cell apoptotic process;GO:0033673//negative regulation of kinase activity;GO:0032024//positive regulation of insulin secretion;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0007420//brain development;GO:0019216//regulation of lipid metabolic process;GO:0010748//negative regulation of plasma membrane long-chain fatty acid transport;GO:0030335//positive regulation of cell migration;GO:0032869//cellular response to insulin stimulus;GO:0008283//cell proliferation;GO:0046326//positive regulation of glucose import;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0010907//positive regulation of glucose metabolic process;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0009749//response to glucose;GO:0055088//lipid homeostasis;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005515//protein binding;GO:0071889//14-3-3 protein binding;GO:0043548//phosphatidylinositol 3-kinase binding;GO:0019901//protein kinase binding;GO:0004871//signal transducer activity;GO:0019904//protein domain specific binding;GO:0005158//insulin receptor binding;GO:0019903//protein phosphatase binding,K07187//Type II diabetes mellitus;Aldosterone-regulated sodium reabsorption;Insulin signaling pathway;Neurotrophin signaling pathway;Adipocytokine signaling pathway
8661,0,30,1,48,186,0,76,0,110,0,49,0,"EIF3A;eukaryotic translation initiation factor 3, subunit A","GO:0016282//eukaryotic 43S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005730//nucleolus;GO:0005634//nucleus",GO:0006413//translational initiation;GO:0006412//translation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0010467//gene expression;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005198//structural molecule activity;GO:0003743//translation initiation factor activity,K03254//RNA transport
8662,112,27,1,44,167,31,26,1,22,0,0,0,"EIF3B;eukaryotic translation initiation factor 3, subunit B","GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0070062//extracellular vesicular exosome",GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0006412//translation;GO:0001731//formation of translation preinitiation complex;GO:0006446//regulation of translational initiation,GO:0003743//translation initiation factor activity;GO:0032947//protein complex scaffold;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0031369//translation initiation factor binding,K03253//RNA transport
8664,0,65,1,40,160,0,0,0,25,0,0,0,"EIF3D;eukaryotic translation initiation factor 3, subunit D","GO:0016020//membrane;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005829//cytosol",GO:0044267//cellular protein metabolic process;GO:0001732//formation of cytoplasmic translation initiation complex;GO:0010467//gene expression;GO:0006412//translation;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0006413//translational initiation,GO:0003743//translation initiation factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K03251//RNA transport
8665,0,37,0,28,30,0,1,0,37,0,0,0,"EIF3F;eukaryotic translation initiation factor 3, subunit F","GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005829//cytosol;GO:0033290//eukaryotic 48S preinitiation complex;GO:0016020//membrane;GO:0005852//eukaryotic translation initiation factor 3 complex",GO:0006508//proteolysis;GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0006412//translation;GO:0016579//protein deubiquitination;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex,GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity;GO:0031369//translation initiation factor binding;GO:0003743//translation initiation factor activity,K03249//RNA transport
8666,0,27,0,7,71,0,0,0,13,0,0,0,"EIF3G;eukaryotic translation initiation factor 3, subunit G",GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006446//regulation of translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0006412//translation;GO:0006413//translational initiation,GO:0003743//translation initiation factor activity;GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K03248//RNA transport
8667,0,12,0,92,228,0,0,35,11,0,0,0,"EIF3H;eukaryotic translation initiation factor 3, subunit H","GO:0070062//extracellular vesicular exosome;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0016282//eukaryotic 43S preinitiation complex;GO:0005829//cytosol;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0033290//eukaryotic 48S preinitiation complex;GO:0016020//membrane",GO:0001731//formation of translation preinitiation complex;GO:0006446//regulation of translational initiation;GO:0006412//translation;GO:0006413//translational initiation;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003743//translation initiation factor activity,K03247//Measles;RNA transport
8668,1,71,3,38,192,7,2,0,12,0,17,31,"EIF3I;eukaryotic translation initiation factor 3, subunit I","GO:0070062//extracellular vesicular exosome;GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0016282//eukaryotic 43S preinitiation complex;GO:0071541//eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005829//cytosol",GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0001731//formation of translation preinitiation complex;GO:0006446//regulation of translational initiation;GO:0006412//translation;GO:0006413//translational initiation,GO:0005515//protein binding;GO:0003743//translation initiation factor activity,K03246//RNA transport
8669,0,59,2,76,140,18,1,0,7,0,0,0,"EIF3J;eukaryotic translation initiation factor 3, subunit J",GO:0033290//eukaryotic 48S preinitiation complex;GO:0005852//eukaryotic translation initiation factor 3 complex;GO:0005829//cytosol;GO:0016282//eukaryotic 43S preinitiation complex,GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0001731//formation of translation preinitiation complex;GO:0006446//regulation of translational initiation;GO:0006412//translation,GO:0005515//protein binding;GO:0003743//translation initiation factor activity,K03245//RNA transport
867,0,0,0,2,50,95,18,48,45,0,6,202,"CBL;Cbl proto-oncogene, E3 ubiquitin protein ligase",GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016600//flotillin complex,"GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0007166//cell surface receptor signaling pathway;GO:0048260//positive regulation of receptor-mediated endocytosis;GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0014068//positive regulation of phosphatidylinositol 3-kinase signaling",GO:0046875//ephrin receptor binding;GO:0016874//ligase activity;GO:0004871//signal transducer activity;GO:0017124//SH3 domain binding;GO:0001784//phosphotyrosine binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0005509//calcium ion binding,K04707//Pathways in cancer;Bacterial invasion of epithelial cells;Endocytosis;Insulin signaling pathway;Jak-STAT signaling pathway;Ubiquitin mediated proteolysis;T cell receptor signaling pathway;Chronic myeloid leukemia;ErbB signaling pathway;Measles
8671,0,48,0,12,135,13,87,0,84,112,1,60,"SLC4A4;solute carrier family 4 (sodium bicarbonate cotransporter), member 4",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane,GO:0035725//sodium ion transmembrane transport;GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0006810//transport,GO:0008510//sodium:bicarbonate symporter activity;GO:0005515//protein binding;GO:0005452//inorganic anion exchanger activity,K13575//Proximal tubule bicarbonate reclamation;Pancreatic secretion;Bile secretion
8672,39,19,0,18,0,0,45,1,56,0,3,0,"EIF4G3;eukaryotic translation initiation factor 4 gamma, 3",GO:0016281//eukaryotic translation initiation factor 4F complex;GO:0005829//cytosol,GO:0016032//viral process;GO:0006446//regulation of translational initiation;GO:0045727//positive regulation of translation;GO:0060903//positive regulation of meiosis I;GO:0006413//translational initiation;GO:0007283//spermatogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0019221//cytokine-mediated signaling pathway,"GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0003743//translation initiation factor activity;GO:0000339//RNA cap binding",K03260//RNA transport;Viral myocarditis
8673,0,1,2,14,87,16,0,105,6,0,0,0,VAMP8;vesicle-associated membrane protein 8,GO:0030667//secretory granule membrane;GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0031902//late endosome membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0031201//SNARE complex;GO:0005886//plasma membrane;GO:0005765//lysosomal membrane,GO:0015031//protein transport;GO:0061024//membrane organization;GO:0006892//post-Golgi vesicle-mediated transport;GO:0035493//SNARE complex assembly;GO:0030100//regulation of endocytosis;GO:0046718//viral entry into host cell;GO:0000046//autophagic vacuole fusion,GO:0019905//syntaxin binding,K08512//SNARE interactions in vesicular transport
8674,0,0,1,12,39,0,0,0,23,0,13,0,VAMP4;vesicle-associated membrane protein 4,GO:0005764//lysosome;GO:0005802//trans-Golgi network;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0000139//Golgi membrane;GO:0005768//endosome;GO:0031201//SNARE complex,GO:0042996//regulation of Golgi to plasma membrane protein transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0035493//SNARE complex assembly,-,K08513//SNARE interactions in vesicular transport
8675,0,0,0,1,2,0,0,0,24,0,0,0,STX16;syntaxin 16,GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0031201//SNARE complex;GO:0043231//intracellular membrane-bounded organelle;GO:0005925//focal adhesion;GO:0005730//nucleolus,"GO:0006891//intra-Golgi vesicle-mediated transport;GO:0042147//retrograde transport, endosome to Golgi;GO:0006886//intracellular protein transport",GO:0005515//protein binding;GO:0005484//SNAP receptor activity,K08489//SNARE interactions in vesicular transport
8676,7,0,0,0,0,12,22,0,9,0,12,0,STX11;syntaxin 11,GO:0016020//membrane;GO:0005794//Golgi apparatus,GO:0006886//intracellular protein transport;GO:0043316//cytotoxic T cell degranulation;GO:0043320//natural killer cell degranulation;GO:0043312//neutrophil degranulation;GO:0061025//membrane fusion,GO:0005484//SNAP receptor activity;GO:0005515//protein binding,K08487//SNARE interactions in vesicular transport
8677,0,0,0,5,5,0,11,0,11,0,3,0,STX10;syntaxin 10,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0031201//SNARE complex,"GO:0006906//vesicle fusion;GO:0048193//Golgi vesicle transport;GO:0006886//intracellular protein transport;GO:0042147//retrograde transport, endosome to Golgi",GO:0005484//SNAP receptor activity,K08498//SNARE interactions in vesicular transport
8678,0,104,1,72,43,0,0,22,13,0,0,0,"BECN1;beclin 1, autophagy related",GO:0030425//dendrite;GO:0045335//phagocytic vesicle;GO:0016020//membrane;GO:0005634//nucleus;GO:0005802//trans-Golgi network;GO:0043234//protein complex,GO:0033197//response to vitamin E;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0007040//lysosome organization;GO:0050435//beta-amyloid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0008285//negative regulation of cell proliferation;GO:0042493//response to drug;GO:0071275//cellular response to aluminum ion;GO:0048666//neuron development;GO:0006968//cellular defense response;GO:0001666//response to hypoxia;GO:0000045//autophagic vacuole assembly;GO:0016032//viral process;GO:0016239//positive regulation of macroautophagy;GO:0000910//cytokinesis;GO:0051607//defense response to virus;GO:0050790//regulation of catalytic activity,GO:0005515//protein binding,K08334//Regulation of autophagy
868,1,23,0,7,58,11,0,0,54,0,0,315,"CBLB;Cbl proto-oncogene B, E3 ubiquitin protein ligase",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0050860//negative regulation of T cell receptor signaling pathway;GO:0045732//positive regulation of protein catabolic process;GO:0007165//signal transduction;GO:0006607//NLS-bearing protein import into nucleus;GO:0002669//positive regulation of T cell anergy;GO:0016567//protein ubiquitination;GO:0042110//T cell activation;GO:0035556//intracellular signal transduction;GO:0007166//cell surface receptor signaling pathway;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0006955//immune response,GO:0001784//phosphotyrosine binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity;GO:0008270//zinc ion binding,K04707//Measles;ErbB signaling pathway;Chronic myeloid leukemia;T cell receptor signaling pathway;Ubiquitin mediated proteolysis;Jak-STAT signaling pathway;Insulin signaling pathway;Bacterial invasion of epithelial cells;Endocytosis;Pathways in cancer
8682,193,86,35,46,203,0,1,0,19,0,0,0,PEA15;phosphoprotein enriched in astrocytes 15,GO:0005875//microtubule associated complex;GO:0005737//cytoplasm,GO:0008643//carbohydrate transport;GO:0046325//negative regulation of glucose import;GO:0000077//DNA damage checkpoint;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0043278//response to morphine;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0006810//transport;GO:0006915//apoptotic process,GO:0005515//protein binding,-
8683,12,31,53,30,123,0,0,0,0,0,28,0,SRSF9;serine/arginine-rich splicing factor 9,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0048025//negative regulation of mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0031124//mRNA 3'-end processing;GO:0006376//mRNA splice site selection;GO:0006406//mRNA export from nucleus",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K12890//Herpes simplex infection;Spliceosome
8685,0,9,0,0,0,0,93,0,22,0,0,0,MARCO;macrophage receptor with collagenous structure,GO:0005887//integral component of plasma membrane;GO:0005581//collagen trimer;GO:0005886//plasma membrane;GO:0030666//endocytic vesicle membrane,GO:0043277//apoptotic cell clearance;GO:0007166//cell surface receptor signaling pathway;GO:0002221//pattern recognition receptor signaling pathway;GO:0006898//receptor-mediated endocytosis;GO:0045087//innate immune response,GO:0005044//scavenger receptor activity;GO:0008329//signaling pattern recognition receptor activity;GO:0004888//transmembrane signaling receptor activity,K13884//Phagosome
8687,0,0,0,0,0,0,0,0,7,0,0,0,KRT38;keratin 38,GO:0005882//intermediate filament;GO:0070062//extracellular vesicular exosome,-,GO:0005198//structural molecule activity,K07604//Pathogenic Escherichia coli infection;Staphylococcus aureus infection
8689,0,0,0,0,0,6,0,0,0,145,0,0,KRT36;keratin 36,GO:0070062//extracellular vesicular exosome;GO:0005882//intermediate filament,GO:0045616//regulation of keratinocyte differentiation,GO:0030280//structural constituent of epidermis,K07604//Staphylococcus aureus infection;Pathogenic Escherichia coli infection
869,0,0,0,0,0,0,0,0,4,0,0,0,CBLN1;cerebellin 1 precursor,GO:0030054//cell junction;GO:0005576//extracellular region;GO:0045211//postsynaptic membrane,GO:0009306//protein secretion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0021707//cerebellar granule cell differentiation;GO:0051965//positive regulation of synapse assembly,GO:0042803//protein homodimerization activity,K03986//Systemic lupus erythematosus;Prion diseases;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades;K07296//Adipocytokine signaling pathway;PPAR signaling pathway;Type II diabetes mellitus;K03988//Chagas disease (American trypanosomiasis);Prion diseases;Systemic lupus erythematosus;Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades;K03987//Systemic lupus erythematosus;Prion diseases;Chagas disease (American trypanosomiasis);Staphylococcus aureus infection;Pertussis;Complement and coagulation cascades
8690,4,0,0,12,37,16,0,0,8,0,0,0,JRKL;JRK-like,GO:0005634//nucleus,GO:0007417//central nervous system development,GO:0003677//DNA binding,-
8692,0,0,0,0,0,29,8,144,3,0,0,1,HYAL2;hyaluronoglucosaminidase 2,GO:0005783//endoplasmic reticulum;GO:0045121//membrane raft;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0031410//cytoplasmic vesicle;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0030139//endocytic vesicle;GO:0031362//anchored component of external side of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0046658//anchored component of plasma membrane;GO:0005764//lysosome,GO:2000484//positive regulation of interleukin-8 secretion;GO:0071493//cellular response to UV-B;GO:0006027//glycosaminoglycan catabolic process;GO:0019087//transformation of host cell by virus;GO:0042117//monocyte activation;GO:0035810//positive regulation of urine volume;GO:0044281//small molecule metabolic process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043407//negative regulation of MAP kinase activity;GO:2000778//positive regulation of interleukin-6 secretion;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0060586//multicellular organismal iron ion homeostasis;GO:0005975//carbohydrate metabolic process;GO:0051607//defense response to virus;GO:0048705//skeletal system morphogenesis;GO:0030212//hyaluronan metabolic process;GO:0009615//response to virus;GO:0030308//negative regulation of cell growth;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0000302//response to reactive oxygen species;GO:0070295//renal water absorption;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0051216//cartilage development;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0001822//kidney development;GO:0046677//response to antibiotic;GO:0046718//viral entry into host cell;GO:0071347//cellular response to interleukin-1;GO:0050729//positive regulation of inflammatory response;GO:0010764//negative regulation of fibroblast migration;GO:0042307//positive regulation of protein import into nucleus;GO:0051898//negative regulation of protein kinase B signaling;GO:0010259//multicellular organismal aging;GO:0030203//glycosaminoglycan metabolic process;GO:0030214//hyaluronan catabolic process;GO:0071356//cellular response to tumor necrosis factor;GO:0019064//fusion of virus membrane with host plasma membrane,GO:0001618//virus receptor activity;GO:0005515//protein binding;GO:0005540//hyaluronic acid binding;GO:0019899//enzyme binding;GO:0030971//receptor tyrosine kinase binding;GO:0004415//hyalurononglucosaminidase activity;GO:0050431//transforming growth factor beta binding;GO:0030294//receptor signaling protein tyrosine kinase inhibitor activity;GO:0033906//hyaluronoglucuronidase activity,"K01197//Lysosome;Arginine and proline metabolism;Glycosaminoglycan degradation;Alanine, aspartate and glutamate metabolism;Metabolic pathways"
8694,270,241,125,246,335,1,0,199,44,1,333,403,DGAT1;diacylglycerol O-acyltransferase 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0036155//acylglycerol acyl-chain remodeling;GO:0035336//long-chain fatty-acyl-CoA metabolic process;GO:0006641//triglyceride metabolic process;GO:0019915//lipid storage;GO:0046339//diacylglycerol metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0042572//retinol metabolic process;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0034379//very-low-density lipoprotein particle assembly;GO:0019432//triglyceride biosynthetic process;GO:0044281//small molecule metabolic process,"GO:0005515//protein binding;GO:0050252//retinol O-fatty-acyltransferase activity;GO:0004144//diacylglycerol O-acyltransferase activity;GO:0016746//transferase activity, transferring acyl groups",K11155//Retinol metabolism;Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption
8697,0,17,0,33,19,0,16,0,35,0,0,0,CDC23;cell division cycle 23,GO:0005654//nucleoplasm;GO:0005622//intracellular;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex,GO:0007067//mitotic nuclear division;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0000278//mitotic cell cycle;GO:0007096//regulation of exit from mitosis;GO:0007094//mitotic spindle assembly checkpoint;GO:0007080//mitotic metaphase plate congression;GO:0007091//metaphase/anaphase transition of mitotic cell cycle,GO:0004842//ubiquitin-protein transferase activity,K03355//Meiosis - yeast;HTLV-I infection;Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast
8698,0,0,0,0,0,0,7,16,0,0,0,0,S1PR4;sphingosine-1-phosphate receptor 4,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007202//activation of phospholipase C activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007189//adenylate cyclase-activating G-protein coupled receptor signaling pathway;GO:0006955//immune response;GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration,GO:0038036//sphingosine-1-phosphate receptor activity;GO:0008289//lipid binding;GO:0004930//G-protein coupled receptor activity,K04293//Neuroactive ligand-receptor interaction
87,1,7,0,2,11,0,9,79,20,4,6,0,"ACTN1;actinin, alpha 1",GO:0031093//platelet alpha granule lumen;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005916//fascia adherens;GO:0005634//nucleus;GO:0042995//cell projection;GO:0031143//pseudopodium;GO:0005615//extracellular space;GO:0005925//focal adhesion;GO:0030018//Z disc;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043197//dendritic spine;GO:0001726//ruffle;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0051271//negative regulation of cellular component movement;GO:0030168//platelet activation;GO:0051017//actin filament bundle assembly;GO:0042981//regulation of apoptotic process;GO:0048041//focal adhesion assembly;GO:0030198//extracellular matrix organization;GO:0002576//platelet degranulation;GO:0034329//cell junction assembly;GO:0007596//blood coagulation;GO:0051764//actin crosslink formation,GO:0019904//protein domain specific binding;GO:0017166//vinculin binding;GO:0051015//actin filament binding;GO:0003725//double-stranded RNA binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0044325//ion channel binding;GO:0005509//calcium ion binding,K05699//Adherens junction;Amoebiasis;Focal adhesion;Systemic lupus erythematosus;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
8701,111,1,2,24,62,92,0,124,178,0,44,0,"DNAH11;dynein, axonemal, heavy chain 11",GO:0005737//cytoplasm;GO:0030286//dynein complex;GO:0005874//microtubule;GO:0005929//cilium,GO:0007018//microtubule-based movement;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity,K10408//Huntington's disease
8702,0,0,0,0,11,0,31,0,6,0,0,0,"B4GALT4;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4",GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane,GO:0018279//protein N-linked glycosylation via asparagine;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006643//membrane lipid metabolic process;GO:0018146//keratan sulfate biosynthetic process;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process,GO:0046872//metal ion binding;GO:0008378//galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity,K07969//Metabolic pathways;Glycosaminoglycan biosynthesis - keratan sulfate;Glycosphingolipid biosynthesis - lacto and neolacto series
8703,0,0,0,7,6,12,0,0,0,0,9,0,"B4GALT3;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3",GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0000139//Golgi membrane;GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0005975//carbohydrate metabolic process;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process,"GO:0003945//N-acetyllactosamine synthase activity;GO:0008378//galactosyltransferase activity;GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0046872//metal ion binding",K07968//N-Glycan biosynthesis;Metabolic pathways;Other types of O-glycan biosynthesis;Glycosaminoglycan biosynthesis - keratan sulfate;Glycosphingolipid biosynthesis - lacto and neolacto series
8704,66,0,0,0,37,7,0,1,21,0,0,0,"B4GALT2;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2",GO:0016021//integral component of membrane;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane,GO:0005975//carbohydrate metabolic process;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process,"GO:0004461//lactose synthase activity;GO:0046872//metal ion binding;GO:0003831//beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945//N-acetyllactosamine synthase activity;GO:0008378//galactosyltransferase activity",K07967//Metabolic pathways;Galactose metabolism;N-Glycan biosynthesis;Glycosphingolipid biosynthesis - lacto and neolacto series;Other types of O-glycan biosynthesis;Glycosaminoglycan biosynthesis - keratan sulfate
8705,0,0,0,0,0,0,1,2,0,0,0,0,"B3GALT4;UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006486//protein glycosylation,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047915//ganglioside galactosyltransferase activity",K00715//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
8706,0,0,0,0,2,0,0,0,16,0,10,0,"B3GALNT1;beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0009312//oligosaccharide biosynthetic process;GO:0006486//protein glycosylation,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity;GO:0047273//galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity",K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways
8707,101,0,0,0,0,0,0,0,0,0,0,0,"B3GALT2;UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0009312//oligosaccharide biosynthetic process;GO:0006486//protein glycosylation,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity",K07820//Metabolic pathways;Glycosphingolipid biosynthesis - lacto and neolacto series
8708,0,0,0,0,0,0,0,0,14,0,0,0,"B3GALT1;UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0009312//oligosaccharide biosynthetic process;GO:0006486//protein glycosylation,"GO:0008499//UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity",K07819//Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways
871,0,0,0,0,0,3,13,23,11,39,0,0,"SERPINH1;serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)",GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0030199//collagen fibril organization;GO:0030162//regulation of proteolysis;GO:0030198//extracellular matrix organization;GO:0010951//negative regulation of endopeptidase activity;GO:0006986//response to unfolded protein;GO:0051604//protein maturation;GO:0032964//collagen biosynthetic process,GO:0051082//unfolded protein binding;GO:0044822//poly(A) RNA binding;GO:0004867//serine-type endopeptidase inhibitor activity;GO:0005518//collagen binding,-
8710,0,0,0,0,0,5,16,0,45,0,0,71,"SERPINB7;serpin peptidase inhibitor, clade B (ovalbumin), member 7",GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0030162//regulation of proteolysis;GO:0010951//negative regulation of endopeptidase activity;GO:0090362//positive regulation of platelet-derived growth factor production;GO:0032967//positive regulation of collagen biosynthetic process;GO:0032914//positive regulation of transforming growth factor beta1 production;GO:0072126//positive regulation of glomerular mesangial cell proliferation,GO:0004867//serine-type endopeptidase inhibitor activity,-
8711,0,0,0,0,13,0,0,0,64,0,1,0,"TNK1;tyrosine kinase, non-receptor, 1",GO:0016020//membrane;GO:0005829//cytosol;GO:0030054//cell junction;GO:0005737//cytoplasm,GO:0030308//negative regulation of cell growth;GO:0046777//protein autophosphorylation;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007165//signal transduction;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006468//protein phosphorylation,GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004713//protein tyrosine kinase activity;GO:0004715//non-membrane spanning protein tyrosine kinase activity,-
8714,80,0,0,0,0,14,18,4,76,59,1,0,"ABCC3;ATP-binding cassette, sub-family C (CFTR/MRP), member 3",GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0015721//bile acid and bile salt transport;GO:0006200//ATP catabolic process;GO:0044281//small molecule metabolic process;GO:0008206//bile acid metabolic process;GO:0055085//transmembrane transport;GO:0006810//transport,"GO:0005524//ATP binding;GO:0008514//organic anion transmembrane transporter activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05667//Bile secretion;ABC transporters
8715,0,0,0,0,0,0,0,0,11,0,0,0,NOL4;nucleolar protein 4,GO:0005730//nucleolus,-,GO:0003723//RNA binding,-
8717,0,0,0,0,0,0,0,0,12,9,0,0,TRADD;TNFRSF1A-associated via death domain,GO:0043235//receptor complex;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031264//death-inducing signaling complex;GO:0045121//membrane raft;GO:0005829//cytosol,GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0051798//positive regulation of hair follicle development;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0007165//signal transduction;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0051291//protein heterooligomerization;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand,"GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0060090//binding, bridging;GO:0019900//kinase binding;GO:0070513//death domain binding;GO:0004871//signal transducer activity;GO:0042802//identical protein binding;GO:0032403//protein complex binding",K03171//RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;Tuberculosis;NF-kappa B signaling pathway;Hepatitis C;Apoptosis;Adipocytokine signaling pathway
87178,0,0,0,12,29,31,34,0,29,0,0,0,PNPT1;polyribonucleotide nucleotidyltransferase 1,GO:0005739//mitochondrion;GO:0016020//membrane;GO:0005758//mitochondrial intermembrane space;GO:0045025//mitochondrial degradosome;GO:0005737//cytoplasm,"GO:0000958//mitochondrial mRNA catabolic process;GO:0000962//positive regulation of mitochondrial RNA catabolic process;GO:0061014//positive regulation of mRNA catabolic process;GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0034599//cellular response to oxidative stress;GO:0045926//negative regulation of growth;GO:0035928//rRNA import into mitochondrion;GO:0000964//mitochondrial RNA 5'-end processing;GO:0070207//protein homotrimerization;GO:0071850//mitotic cell cycle arrest;GO:0000965//mitochondrial RNA 3'-end processing;GO:0071042//nuclear polyadenylation-dependent mRNA catabolic process;GO:0006401//RNA catabolic process;GO:0043631//RNA polyadenylation;GO:0070584//mitochondrion morphogenesis;GO:0051260//protein homooligomerization;GO:0035458//cellular response to interferon-beta;GO:0006402//mRNA catabolic process;GO:2000627//positive regulation of miRNA catabolic process;GO:0043457//regulation of cellular respiration;GO:2000772//regulation of cellular senescence;GO:0097222//mitochondrial mRNA polyadenylation",GO:0034046//poly(G) binding;GO:0044822//poly(A) RNA binding;GO:0004654//polyribonucleotide nucleotidyltransferase activity;GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0008266//poly(U) RNA binding;GO:0035198//miRNA binding,K00962//RNA degradation;Propanoate metabolism;Pyrimidine metabolism;Purine metabolism
8718,0,0,0,0,0,15,32,0,34,0,1,0,"TNFRSF25;tumor necrosis factor receptor superfamily, member 25",GO:0005887//integral component of plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005576//extracellular region,GO:0007165//signal transduction;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0042981//regulation of apoptotic process,GO:0004872//receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity,K05160//Cytokine-cytokine receptor interaction
8720,0,19,1,47,33,7,0,0,32,0,33,0,"MBTPS1;membrane-bound transcription factor peptidase, site 1",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005795//Golgi stack;GO:0005794//Golgi apparatus;GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044281//small molecule metabolic process;GO:0006629//lipid metabolic process;GO:0042990//regulation of transcription factor import into nucleus;GO:0044267//cellular protein metabolic process;GO:0008203//cholesterol metabolic process;GO:0006508//proteolysis;GO:0007040//lysosome organization;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0004252//serine-type endopeptidase activity,K08653//Protein processing in endoplasmic reticulum
8721,0,11,1,6,33,0,0,0,2,0,0,0,EDF1;endothelial differentiation-related factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005669//transcription factor TFIID complex;GO:0005730//nucleolus;GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular,"GO:0045446//endothelial cell differentiation;GO:0007275//multicellular organismal development;GO:0019216//regulation of lipid metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0043388//positive regulation of DNA binding;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0005516//calmodulin binding;GO:0043565//sequence-specific DNA binding;GO:0004402//histone acetyltransferase activity;GO:0008168//methyltransferase activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
8722,97,0,0,1,0,0,0,0,15,0,0,0,CTSF;cathepsin F,GO:0005764//lysosome;GO:0031982//vesicle;GO:0043202//lysosomal lumen;GO:0070062//extracellular vesicular exosome,GO:0008219//cell death;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0006508//proteolysis,GO:0004197//cysteine-type endopeptidase activity,K01373//Lysosome
8723,0,0,0,20,77,0,0,123,34,0,3,0,SNX4;sorting nexin 4,GO:0005868//cytoplasmic dynein complex;GO:0016020//membrane;GO:0031901//early endosome membrane;GO:0005737//cytoplasm;GO:0043234//protein complex,GO:0032456//endocytic recycling;GO:0015031//protein transport;GO:0006886//intracellular protein transport,GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005158//insulin receptor binding;GO:0005154//epidermal growth factor receptor binding,K08545//MAPK signaling pathway - fly
8724,0,0,0,0,5,0,0,0,0,0,0,0,SNX3;sorting nexin 3,GO:0043231//intracellular membrane-bounded organelle;GO:0010008//endosome membrane;GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005737//cytoplasm,GO:0051224//negative regulation of protein transport;GO:0033572//transferrin transport;GO:0033157//regulation of intracellular protein transport;GO:0042541//hemoglobin biosynthetic process;GO:0032268//regulation of cellular protein metabolic process;GO:0006886//intracellular protein transport;GO:0010324//membrane invagination;GO:0042177//negative regulation of protein catabolic process;GO:0046597//negative regulation of viral entry into host cell,GO:0005515//protein binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0019903//protein phosphatase binding,K08545//MAPK signaling pathway - fly
8725,74,2,0,21,130,0,0,0,38,0,0,0,"URI1;URI1, prefoldin-like chaperone","GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005739//mitochondrion;GO:0016272//prefoldin complex;GO:0030425//dendrite;GO:0005665//DNA-directed RNA polymerase II, core complex","GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001558//regulation of cell growth;GO:0010923//negative regulation of phosphatase activity;GO:0009615//response to virus;GO:0071363//cellular response to growth factor stimulus;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006457//protein folding;GO:0071383//cellular response to steroid hormone stimulus;GO:2001243//negative regulation of intrinsic apoptotic signaling pathway",GO:0003682//chromatin binding;GO:0004864//protein phosphatase inhibitor activity;GO:0001106//RNA polymerase II transcription corepressor activity;GO:0051082//unfolded protein binding;GO:0005515//protein binding,-
8726,0,0,0,1,0,0,0,0,0,3,0,0,EED;embryonic ectoderm development,GO:0005730//nucleolus;GO:0001739//sex chromatin;GO:0045120//pronucleus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0035098//ESC/E(Z) complex;GO:0005654//nucleoplasm,"GO:0061087//positive regulation of histone H3-K27 methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006351//transcription, DNA-templated;GO:0016571//histone methylation",GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0042054//histone methyltransferase activity,-
8727,0,39,0,6,6,31,21,2,27,0,8,0,"CTNNAL1;catenin (cadherin-associated protein), alpha-like 1",GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0007266//Rho protein signal transduction;GO:0007155//cell adhesion,GO:0045296//cadherin binding;GO:0005198//structural molecule activity,K12597//RNA degradation;K05691//Leukocyte transendothelial migration;Adherens junction;Bacterial invasion of epithelial cells;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;Endometrial cancer;Pathways in cancer
8728,41,0,1,0,0,29,24,13,23,0,10,0,ADAM19;ADAM metallopeptidase domain 19,GO:0016021//integral component of membrane,GO:0006509//membrane protein ectodomain proteolysis;GO:0007507//heart development,GO:0017124//SH3 domain binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
8729,0,31,2,26,95,51,8,0,74,0,0,0,GBF1;golgi brefeldin A resistant guanine nucleotide exchange factor 1,GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0005801//cis-Golgi network;GO:0000139//Golgi membrane;GO:0005777//peroxisome;GO:0005802//trans-Golgi network;GO:0005795//Golgi stack;GO:0005739//mitochondrion;GO:0005788//endoplasmic reticulum lumen,"GO:0061024//membrane organization;GO:0006892//post-Golgi vesicle-mediated transport;GO:0032012//regulation of ARF protein signal transduction;GO:0048205//COPI coating of Golgi vesicle;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0043547//positive regulation of GTPase activity;GO:0016032//viral process;GO:0016192//vesicle-mediated transport",GO:0005515//protein binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
873,0,1,0,12,28,15,29,0,0,0,6,0,CBR1;carbonyl reductase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0031982//vesicle,GO:0055114//oxidation-reduction process;GO:0019369//arachidonic acid metabolic process;GO:0042373//vitamin K metabolic process;GO:0017144//drug metabolic process;GO:0030855//epithelial cell differentiation;GO:0044281//small molecule metabolic process;GO:0019371//cyclooxygenase pathway,"GO:0016655//oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor;GO:0004090//carbonyl reductase (NADPH) activity;GO:0050221//prostaglandin-E2 9-reductase activity;GO:0047021//15-hydroxyprostaglandin dehydrogenase (NADP+) activity",K00079//Metabolism of xenobiotics by cytochrome P450;Metabolic pathways;Arachidonic acid metabolism
8731,69,0,0,25,50,4,47,0,83,1,0,0,RNMT;RNA (guanine-7-) methyltransferase,GO:0005845//mRNA cap binding complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0043235//receptor complex;GO:0005654//nucleoplasm,GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0036265//RNA (guanine-N7)-methylation;GO:0010467//gene expression;GO:0006370//7-methylguanosine mRNA capping,GO:0005515//protein binding;GO:0004482//mRNA (guanine-N7-)-methyltransferase activity;GO:0003723//RNA binding,K00565//mRNA surveillance pathway
8732,27,0,0,13,16,7,22,11,48,0,0,0,RNGTT;RNA guanylyltransferase and 5'-phosphatase,GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006366//transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0006396//RNA processing;GO:0010467//gene expression;GO:0098507//polynucleotide 5' dephosphorylation;GO:0006370//7-methylguanosine mRNA capping,GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0005525//GTP binding;GO:0050355//triphosphatase activity;GO:0004651//polynucleotide 5'-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004484//mRNA guanylyltransferase activity,K13917//mRNA surveillance pathway
8733,0,0,0,0,0,0,0,0,0,29,0,383,GPAA1;glycosylphosphatidylinositol anchor attachment 1,GO:0005789//endoplasmic reticulum membrane;GO:0042765//GPI-anchor transamidase complex;GO:0016020//membrane,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0006621//protein retention in ER lumen;GO:0016255//attachment of GPI anchor to protein;GO:0006461//protein complex assembly,GO:0015631//tubulin binding;GO:0034235//GPI anchor binding;GO:0003923//GPI-anchor transamidase activity;GO:0005515//protein binding,K05289//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
8735,0,0,0,0,0,16,44,0,24,0,0,284,"MYH13;myosin, heavy chain 13, skeletal muscle",GO:0005859//muscle myosin complex;GO:0032982//myosin filament;GO:0070062//extracellular vesicular exosome;GO:0030016//myofibril,GO:0008152//metabolic process;GO:0009267//cellular response to starvation;GO:0006936//muscle contraction,GO:0005516//calmodulin binding;GO:0005524//ATP binding;GO:0003779//actin binding;GO:0000146//microfilament motor activity,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
8736,0,0,0,0,0,43,26,0,65,208,0,0,MYOM1;myomesin 1,GO:0005863//striated muscle myosin thick filament;GO:0031430//M band,GO:0006936//muscle contraction,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0008307//structural constituent of muscle,K12567//Hypertrophic cardiomyopathy (HCM);Dilated cardiomyopathy
8737,0,22,1,29,39,0,0,66,16,132,0,0,RIPK1;receptor (TNFRSF)-interacting serine-threonine kinase 1,GO:0097342//ripoptosome;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0005739//mitochondrion;GO:0043235//receptor complex;GO:0031264//death-inducing signaling complex,GO:0046777//protein autophosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070926//regulation of ATP:ADP antiporter activity;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0060545//positive regulation of necroptotic process;GO:0071363//cellular response to growth factor stimulus;GO:0097191//extrinsic apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0051291//protein heterooligomerization;GO:0006915//apoptotic process;GO:0034612//response to tumor necrosis factor;GO:0007257//activation of JUN kinase activity;GO:0032760//positive regulation of tumor necrosis factor production;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045651//positive regulation of macrophage differentiation;GO:0051260//protein homooligomerization;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0002224//toll-like receptor signaling pathway;GO:0070266//necroptotic process;GO:0071356//cellular response to tumor necrosis factor;GO:0097527//necroptotic signaling pathway;GO:1990000//amyloid fibril formation;GO:0001934//positive regulation of protein phosphorylation;GO:0097190//apoptotic signaling pathway;GO:0032757//positive regulation of interleukin-8 production;GO:0036289//peptidyl-serine autophosphorylation;GO:2001240//negative regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0097343//ripoptosome assembly;GO:0043068//positive regulation of programmed cell death;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0070231//T cell apoptotic process;GO:0046330//positive regulation of JNK cascade;GO:0034142//toll-like receptor 4 signaling pathway;GO:0044257//cellular protein catabolic process,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0070513//death domain binding;GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0031625//ubiquitin protein ligase binding;GO:0032403//protein complex binding;GO:0005123//death receptor binding;GO:0005524//ATP binding,K02861//Toll-like receptor signaling pathway;RIG-I-like receptor signaling pathway;Epstein-Barr virus infection;NF-kappa B signaling pathway;Cytosolic DNA-sensing pathway;Hepatitis C;Apoptosis
8738,0,0,0,9,15,0,0,0,20,129,0,1,CRADD;CASP2 and RIPK1 domain containing adaptor with death domain,GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors","GO:0002020//protease binding;GO:0070513//death domain binding;GO:0030674//protein binding, bridging;GO:0005515//protein binding",-
8739,0,0,0,0,0,0,1,0,23,0,0,0,"HRK;harakiri, BCL2 interacting protein",GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006915//apoptotic process;GO:0032464//positive regulation of protein homooligomerization;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria,GO:0005515//protein binding,-
874,0,141,31,178,269,0,0,162,4,66,104,0,CBR3;carbonyl reductase 3,GO:0005730//nucleolus;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0055114//oxidation-reduction process;GO:0042376//phylloquinone catabolic process;GO:0050890//cognition,GO:0000253//3-keto sterol reductase activity;GO:0070402//NADPH binding;GO:0004090//carbonyl reductase (NADPH) activity,K00084//Metabolism of xenobiotics by cytochrome P450;Metabolic pathways;Arachidonic acid metabolism
8740,0,0,0,0,0,0,0,0,5,0,0,0,"TNFSF14;tumor necrosis factor (ligand) superfamily, member 14",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0005737//cytoplasm,GO:0043029//T cell homeostasis;GO:0007165//signal transduction;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0042098//T cell proliferation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0031295//T cell costimulation;GO:0042110//T cell activation;GO:0071260//cellular response to mechanical stimulus;GO:0006955//immune response;GO:0010820//positive regulation of T cell chemotaxis;GO:0006915//apoptotic process,GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005102//receptor binding;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process,K05477//Herpes simplex infection;Cytokine-cytokine receptor interaction;NF-kappa B signaling pathway
8741,0,0,0,1,1,0,0,0,0,0,6,0,"TNFSF13;tumor necrosis factor (ligand) superfamily, member 13",GO:0005615//extracellular space;GO:0005829//cytosol;GO:0009897//external side of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,GO:0010467//gene expression;GO:0002636//positive regulation of germinal center formation;GO:0048298//positive regulation of isotype switching to IgA isotypes;GO:0008284//positive regulation of cell proliferation;GO:0002426//immunoglobulin production in mucosal tissue;GO:0007165//signal transduction;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process,GO:0005102//receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding,K05475//Cytokine-cytokine receptor interaction;Rheumatoid arthritis;Intestinal immune network for IgA production
8742,7,0,0,5,0,0,0,0,14,0,1,0,"TNFSF12;tumor necrosis factor (ligand) superfamily, member 12",GO:0005615//extracellular space;GO:0048471//perinuclear region of cytoplasm;GO:0005887//integral component of plasma membrane,GO:0030154//cell differentiation;GO:0045766//positive regulation of angiogenesis;GO:0043542//endothelial cell migration;GO:0001525//angiogenesis;GO:0007165//signal transduction;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0006955//immune response;GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation,GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0005102//receptor binding,K05474//Cytokine-cytokine receptor interaction
8743,0,0,0,12,10,0,12,0,0,0,4,0,"TNFSF10;tumor necrosis factor (ligand) superfamily, member 10",GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome,GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007267//cell-cell signaling;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0032868//response to insulin;GO:0007165//signal transduction;GO:0006955//immune response;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006915//apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:0008584//male gonad development;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand,GO:0005102//receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0046872//metal ion binding;GO:0005515//protein binding,K04721//Influenza A;Measles;Cytokine-cytokine receptor interaction;Natural killer cell mediated cytotoxicity;Apoptosis
8744,0,0,0,0,0,0,0,126,13,0,0,0,"TNFSF9;tumor necrosis factor (ligand) superfamily, member 9",GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0032735//positive regulation of interleukin-12 production;GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0006955//immune response;GO:0045585//positive regulation of cytotoxic T cell differentiation;GO:0007165//signal transduction;GO:0042104//positive regulation of activated T cell proliferation;GO:0043011//myeloid dendritic cell differentiation;GO:0032729//positive regulation of interferon-gamma production;GO:0007267//cell-cell signaling;GO:0032755//positive regulation of interleukin-6 production,GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding;GO:0005102//receptor binding,K05472//Cytokine-cytokine receptor interaction
8745,0,0,0,0,0,43,0,0,50,86,1,0,ADAM23;ADAM metallopeptidase domain 23,GO:0005887//integral component of plasma membrane;GO:0005576//extracellular region,GO:0007155//cell adhesion;GO:0007417//central nervous system development;GO:0006508//proteolysis,GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity,-
8747,0,0,0,0,0,56,0,0,23,0,0,0,ADAM21;ADAM metallopeptidase domain 21,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0030424//axon;GO:0043025//neuronal cell body,GO:0006508//proteolysis;GO:0007338//single fertilization;GO:0007339//binding of sperm to zona pellucida;GO:0032504//multicellular organism reproduction,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0004222//metalloendopeptidase activity,-
8748,0,0,0,0,0,18,0,0,37,0,0,0,ADAM20;ADAM metallopeptidase domain 20,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis;GO:0007338//single fertilization;GO:0032504//multicellular organism reproduction;GO:0007339//binding of sperm to zona pellucida,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
8749,0,0,0,0,0,20,3,0,36,0,0,0,ADAM18;ADAM metallopeptidase domain 18,GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0007283//spermatogenesis;GO:0006508//proteolysis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
875,91,39,0,5,95,0,26,17,27,0,20,0,CBS;cystathionine-beta-synthase,GO:0005829//cytosol;GO:0005634//nucleus,GO:0019346//transsulfuration;GO:0006565//L-serine catabolic process;GO:0044281//small molecule metabolic process;GO:0019448//L-cysteine catabolic process;GO:0019343//cysteine biosynthetic process via cystathionine;GO:0034641//cellular nitrogen compound metabolic process;GO:0006535//cysteine biosynthetic process from serine;GO:0006563//L-serine metabolic process;GO:0070814//hydrogen sulfide biosynthetic process;GO:0000096//sulfur amino acid metabolic process;GO:0043418//homocysteine catabolic process;GO:0050667//homocysteine metabolic process,GO:0020037//heme binding;GO:0004122//cystathionine beta-synthase activity;GO:0030554//adenyl nucleotide binding;GO:0019899//enzyme binding;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0072341//modified amino acid binding;GO:0030170//pyridoxal phosphate binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity,"K01697//Cysteine and methionine metabolism;Glycine, serine and threonine metabolism;Sulfur metabolism;Microbial metabolism in diverse environments;Metabolic pathways"
8751,0,0,0,0,0,0,1,0,26,0,0,340,ADAM15;ADAM metallopeptidase domain 15,GO:0042995//cell projection;GO:0005912//adherens junction;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007229//integrin-mediated signaling pathway;GO:0001953//negative regulation of cell-matrix adhesion;GO:0042246//tissue regeneration;GO:0022617//extracellular matrix disassembly;GO:0006508//proteolysis;GO:0007160//cell-matrix adhesion;GO:0006915//apoptotic process;GO:0030574//collagen catabolic process;GO:0060317//cardiac epithelial to mesenchymal transition;GO:0001525//angiogenesis;GO:0030198//extracellular matrix organization;GO:0045087//innate immune response;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:1900121//negative regulation of receptor binding;GO:0070528//protein kinase C signaling,GO:0005178//integrin binding;GO:0005515//protein binding;GO:0008237//metallopeptidase activity;GO:0017124//SH3 domain binding;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
8754,0,1,0,8,32,22,11,0,25,0,0,0,ADAM9;ADAM metallopeptidase domain 9,GO:0031233//intrinsic component of external side of plasma membrane;GO:0005737//cytoplasm;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0016323//basolateral plasma membrane;GO:0005615//extracellular space;GO:0005925//focal adhesion,GO:0007229//integrin-mediated signaling pathway;GO:0071222//cellular response to lipopolysaccharide;GO:0010042//response to manganese ion;GO:0050714//positive regulation of protein secretion;GO:0022617//extracellular matrix disassembly;GO:0034241//positive regulation of macrophage fusion;GO:0051592//response to calcium ion;GO:0007155//cell adhesion;GO:0007160//cell-matrix adhesion;GO:0030216//keratinocyte differentiation;GO:0034612//response to tumor necrosis factor;GO:0051549//positive regulation of keratinocyte migration;GO:0030574//collagen catabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0051088//PMA-inducible membrane protein ectodomain proteolysis;GO:0051384//response to glucocorticoid;GO:0042117//monocyte activation;GO:0030198//extracellular matrix organization;GO:0034616//response to laminar fluid shear stress;GO:0033631//cell-cell adhesion mediated by integrin;GO:0051044//positive regulation of membrane protein ectodomain proteolysis;GO:0042542//response to hydrogen peroxide;GO:0033630//positive regulation of cell adhesion mediated by integrin;GO:0033627//cell adhesion mediated by integrin;GO:0006509//membrane protein ectodomain proteolysis;GO:0000186//activation of MAPKK activity,GO:0005518//collagen binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity;GO:0005178//integrin binding;GO:0005515//protein binding;GO:0043236//laminin binding;GO:0004222//metalloendopeptidase activity;GO:0017124//SH3 domain binding;GO:0005080//protein kinase C binding,-
8755,0,0,0,0,0,0,6,0,0,0,0,0,"ADAM6;ADAM metallopeptidase domain 6, pseudogene",-,-,-,-
8756,0,0,0,0,0,25,0,0,41,0,19,0,ADAM7;ADAM metallopeptidase domain 7,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
8759,0,36,0,4,0,11,0,37,0,0,25,0,"ADAM1A;ADAM metallopeptidase domain 1A, pseudogene",-,-,-,-
8760,0,0,0,0,0,0,5,4,31,0,0,0,CDS2;CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2,GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0044281//small molecule metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process;GO:0016024//CDP-diacylglycerol biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process,GO:0004605//phosphatidate cytidylyltransferase activity,K00981//Phosphatidylinositol signaling system;RNA degradation;Metabolic pathways;Glycerophospholipid metabolism;Shigellosis;Ribosome
8761,0,23,1,38,46,0,0,0,0,0,4,0,"PABPC4;poly(A) binding protein, cytoplasmic 4 (inducible form)",GO:0030529//ribonucleoprotein complex;GO:0010494//cytoplasmic stress granule;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006401//RNA catabolic process;GO:0006396//RNA processing;GO:0006412//translation;GO:0007596//blood coagulation,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0017130//poly(C) RNA binding;GO:0008266//poly(U) RNA binding;GO:0008143//poly(A) binding,K13126//mRNA surveillance pathway;RNA transport;RNA degradation
8763,31,23,0,0,0,0,0,0,0,0,0,0,"CD164;CD164 molecule, sialomucin",GO:0005576//extracellular region;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0005765//lysosomal membrane;GO:0005887//integral component of plasma membrane;GO:0005764//lysosome,GO:0007155//cell adhesion;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007517//muscle organ development;GO:0008285//negative regulation of cell proliferation;GO:0007275//multicellular organismal development;GO:0006955//immune response;GO:0030097//hemopoiesis;GO:0007162//negative regulation of cell adhesion;GO:0007165//signal transduction,GO:0005515//protein binding,K06546//Lysosome
8764,0,0,0,31,15,9,0,134,11,0,30,0,"TNFRSF14;tumor necrosis factor receptor superfamily, member 14",GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0050829//defense response to Gram-negative bacterium;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0002741//positive regulation of cytokine secretion involved in immune response;GO:2000406//positive regulation of T cell migration;GO:0050830//defense response to Gram-positive bacterium;GO:0031295//T cell costimulation;GO:0016032//viral process;GO:0009615//response to virus;GO:0046642//negative regulation of alpha-beta T cell proliferation;GO:0007166//cell surface receptor signaling pathway;GO:0006955//immune response,GO:0001618//virus receptor activity;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K05152//Cytokine-cytokine receptor interaction;Herpes simplex infection
8766,0,84,0,107,446,0,1,0,0,0,0,196,"RAB11A;RAB11A, member RAS oncogene family",GO:0005802//trans-Golgi network;GO:0043234//protein complex;GO:0030133//transport vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0032154//cleavage furrow;GO:0045335//phagocytic vesicle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0055037//recycling endosome;GO:0048471//perinuclear region of cytoplasm;GO:0005739//mitochondrion;GO:0030424//axon;GO:0005771//multivesicular body;GO:0055038//recycling endosome membrane,GO:0007264//small GTPase mediated signal transduction;GO:0016192//vesicle-mediated transport;GO:0000910//cytokinesis;GO:0006833//water transport;GO:0032402//melanosome transport;GO:0031175//neuron projection development;GO:0048227//plasma membrane to endosome transport;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0006184//GTP catabolic process;GO:0072659//protein localization to plasma membrane;GO:0045773//positive regulation of axon extension;GO:0015031//protein transport;GO:1990182//exosomal secretion;GO:0051223//regulation of protein transport;GO:0055085//transmembrane transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0019905//syntaxin binding,K07904//Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Vasopressin-regulated water reabsorption;Endocytosis
8767,0,0,0,7,4,0,50,0,19,0,21,0,RIPK2;receptor-interacting serine-threonine kinase 2,GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0043234//protein complex;GO:0005829//cytosol,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0070555//response to interleukin-1;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0071225//cellular response to muramyl dipeptide;GO:0007165//signal transduction;GO:0070671//response to interleukin-12;GO:0006915//apoptotic process;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0070673//response to interleukin-18;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032729//positive regulation of interferon-gamma production;GO:0032760//positive regulation of tumor necrosis factor production;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0000187//activation of MAPK activity;GO:0002250//adaptive immune response;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0050830//defense response to Gram-positive bacterium;GO:0033091//positive regulation of immature T cell proliferation;GO:0071224//cellular response to peptidoglycan;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0031398//positive regulation of protein ubiquitination;GO:0070423//nucleotide-binding oligomerization domain containing signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0032735//positive regulation of interleukin-12 production;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0050852//T cell receptor signaling pathway;GO:0032743//positive regulation of interleukin-2 production;GO:0034162//toll-like receptor 9 signaling pathway;GO:0070427//nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0042098//T cell proliferation;GO:0045087//innate immune response;GO:0032722//positive regulation of chemokine production;GO:0010800//positive regulation of peptidyl-threonine phosphorylation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0007254//JNK cascade;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0032728//positive regulation of interferon-beta production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0071223//cellular response to lipoteichoic acid;GO:0032727//positive regulation of interferon-alpha production;GO:0043330//response to exogenous dsRNA;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0046330//positive regulation of JNK cascade",GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0050700//CARD domain binding;GO:0042803//protein homodimerization activity;GO:0030274//LIM domain binding;GO:0004871//signal transducer activity;GO:0005524//ATP binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity,K08846//Neurotrophin signaling pathway;Tuberculosis;NOD-like receptor signaling pathway;Shigellosis
8772,0,0,0,1,0,0,15,0,1,0,0,0,FADD;Fas (TNFRSF6)-associated via death domain,GO:0031264//death-inducing signaling complex;GO:0044297//cell body;GO:0097342//ripoptosome;GO:0005829//cytosol;GO:0045121//membrane raft;GO:0043005//neuron projection;GO:0031265//CD95 death-inducing signaling complex,"GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0051607//defense response to virus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002821//positive regulation of adaptive immune response;GO:0042104//positive regulation of activated T cell proliferation;GO:0006915//apoptotic process;GO:0097202//activation of cysteine-type endopeptidase activity;GO:0051291//protein heterooligomerization;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0097191//extrinsic apoptotic signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0097049//motor neuron apoptotic process;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902043//positive regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0032729//positive regulation of interferon-gamma production;GO:0048538//thymus development;GO:0045651//positive regulation of macrophage differentiation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002224//toll-like receptor signaling pathway;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0060546//negative regulation of necroptotic process;GO:0016032//viral process;GO:0001916//positive regulation of T cell mediated cytotoxicity;GO:0097527//necroptotic signaling pathway;GO:0048535//lymph node development;GO:0045862//positive regulation of proteolysis;GO:2000454//positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation;GO:0032757//positive regulation of interleukin-8 production;GO:0097190//apoptotic signaling pathway;GO:0060340//positive regulation of type I interferon-mediated signaling pathway;GO:0070236//negative regulation of activation-induced cell death of T cells;GO:0033077//T cell differentiation in thymus;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0045087//innate immune response;GO:0048536//spleen development;GO:0043029//T cell homeostasis;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0034142//toll-like receptor 4 signaling pathway",GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0035877//death effector domain binding;GO:0005123//death receptor binding;GO:0002020//protease binding,K02373//Pathways in cancer;Chagas disease (American trypanosomiasis);Tuberculosis;Toll-like receptor signaling pathway;Apoptosis;Herpes simplex infection;Alzheimer's disease;RIG-I-like receptor signaling pathway
8773,0,0,1,15,146,0,0,0,10,0,0,0,"SNAP23;synaptosomal-associated protein, 23kDa",GO:0042582//azurophil granule;GO:0042581//specific granule;GO:0045202//synapse;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0005634//nucleus;GO:0005925//focal adhesion;GO:0005730//nucleolus,GO:0061025//membrane fusion;GO:0006903//vesicle targeting;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006887//exocytosis;GO:0061024//membrane organization;GO:0015031//protein transport,GO:0005515//protein binding,K08508//SNARE interactions in vesicular transport;Synaptic vesicle cycle
8774,0,101,2,20,124,0,17,0,17,0,0,0,"NAPG;N-ethylmaleimide-sensitive factor attachment protein, gamma",GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion;GO:0005765//lysosomal membrane,GO:0050821//protein stabilization;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0061025//membrane fusion;GO:0006461//protein complex assembly,GO:0005515//protein binding,K15296//Synaptic vesicle cycle;K10600//Ubiquitin mediated proteolysis
8775,0,134,14,19,76,0,21,0,22,204,28,0,"NAPA;N-ethylmaleimide-sensitive factor attachment protein, alpha",GO:0070044//synaptobrevin 2-SNAP-25-syntaxin-1a complex;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol,"GO:0006886//intracellular protein transport;GO:0045176//apical protein localization;GO:0035494//SNARE complex disassembly;GO:0035249//synaptic transmission, glutamatergic;GO:0061025//membrane fusion;GO:0030182//neuron differentiation;GO:0006892//post-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0010807//regulation of synaptic vesicle priming;GO:0007420//brain development;GO:0006891//intra-Golgi vesicle-mediated transport",GO:0019905//syntaxin binding;GO:0005515//protein binding,K15296//Synaptic vesicle cycle
8776,0,0,0,0,10,0,0,1,42,0,0,0,MTMR1;myotubularin related protein 1,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0044281//small molecule metabolic process,GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity,K01112//Fructose and mannose metabolism
87769,110,41,29,123,98,0,0,0,18,0,31,0,GGACT;gamma-glutamylamine cyclotransferase,GO:0070062//extracellular vesicular exosome,GO:0042219//cellular modified amino acid catabolic process,GO:0003839//gamma-glutamylcyclotransferase activity,-
8777,0,18,0,24,128,19,62,0,39,0,20,0,MPDZ;multiple PDZ domain protein,GO:0005923//tight junction;GO:0043220//Schmidt-Lanterman incisure;GO:0045211//postsynaptic membrane;GO:0030425//dendrite;GO:0031410//cytoplasmic vesicle;GO:0014069//postsynaptic density;GO:0016327//apicolateral plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane,GO:0007155//cell adhesion;GO:0042552//myelination;GO:0016032//viral process,GO:0008022//protein C-terminus binding;GO:0005515//protein binding,K06095//Tight junction
8778,0,0,0,0,0,0,0,0,12,35,0,0,SIGLEC5;sialic acid binding Ig-like lectin 5,GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
8780,0,15,1,37,128,25,0,0,11,0,6,0,RIOK3;RIO kinase 3,-,GO:0007059//chromosome segregation;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
8784,0,0,0,0,0,0,18,0,0,0,0,0,"TNFRSF18;tumor necrosis factor receptor superfamily, member 18",GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region,GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process;GO:0007165//signal transduction;GO:0033209//tumor necrosis factor-mediated signaling pathway,GO:0005031//tumor necrosis factor-activated receptor activity,K05154//Cytokine-cytokine receptor interaction
8785,0,0,0,0,0,26,0,0,15,0,3,0,MATN4;matrilin 4,GO:0005576//extracellular region,GO:0048678//response to axon injury;GO:0030198//extracellular matrix organization,GO:0005515//protein binding,K08132//Protein digestion and absorption;K06238//ECM-receptor interaction;Protein digestion and absorption;Focal adhesion
8786,0,13,51,0,0,0,0,53,18,0,0,0,RGS11;regulator of G-protein signaling 11,GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0044292//dendrite terminus;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0035556//intracellular signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0005096//GTPase activator activity;GO:0031681//G-protein beta-subunit binding;GO:0004871//signal transducer activity,K13765//Cocaine addiction;Phototransduction
8787,0,0,0,0,0,16,25,0,19,0,0,0,RGS9;regulator of G-protein signaling 9,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,"GO:0007212//dopamine receptor signaling pathway;GO:0007603//phototransduction, visible light;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0035556//intracellular signal transduction;GO:0043627//response to estrogen;GO:0007399//nervous system development;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0007601//visual perception",GO:0032403//protein complex binding;GO:0005096//GTPase activator activity;GO:0004871//signal transducer activity,K13765//Cocaine addiction;Phototransduction
8788,0,0,0,0,0,7,0,0,0,0,0,0,DLK1;delta-like 1 homolog (Drosophila),GO:0005615//extracellular space;GO:0016021//integral component of membrane;GO:0009897//external side of plasma membrane,GO:0048706//embryonic skeletal system development;GO:0010468//regulation of gene expression;GO:0030154//cell differentiation;GO:0045746//negative regulation of Notch signaling pathway;GO:0007275//multicellular organismal development;GO:0007219//Notch signaling pathway;GO:0009791//post-embryonic development,-,K06051//Notch signaling pathway
8789,0,79,0,0,12,28,0,44,20,0,18,0,"FBP2;fructose-1,6-bisphosphatase 2",GO:0030018//Z disc;GO:0005634//nucleus;GO:0005829//cytosol;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome,GO:0006094//gluconeogenesis;GO:0016311//dephosphorylation;GO:0005975//carbohydrate metabolic process;GO:0006000//fructose metabolic process;GO:0044281//small molecule metabolic process;GO:0006006//glucose metabolic process,"GO:0042132//fructose 1,6-bisphosphate 1-phosphatase activity;GO:0046872//metal ion binding",K03841//Microbial metabolism in diverse environments;Insulin signaling pathway;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Carbon fixation in photosynthetic organisms;Methane metabolism;Pentose phosphate pathway;Metabolic pathways;Fructose and mannose metabolism
8790,0,0,30,0,0,0,0,0,0,87,0,0,FPGT;fucose-1-phosphate guanylyltransferase,GO:0005737//cytoplasm,GO:0006004//fucose metabolic process,GO:0047341//fucose-1-phosphate guanylyltransferase activity;GO:0003824//catalytic activity;GO:0005525//GTP binding,K00976//Amino sugar and nucleotide sugar metabolism;Fructose and mannose metabolism;Metabolic pathways
8792,0,0,0,0,0,24,0,3,0,0,0,0,"TNFRSF11A;tumor necrosis factor receptor superfamily, member 11a, NFKB activator",GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane,GO:0060749//mammary gland alveolus development;GO:0071848//positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling;GO:0032496//response to lipopolysaccharide;GO:0002250//adaptive immune response;GO:0007267//cell-cell signaling;GO:0001503//ossification;GO:0008284//positive regulation of cell proliferation;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043507//positive regulation of JUN kinase activity;GO:0034097//response to cytokine;GO:0034612//response to tumor necrosis factor;GO:0009314//response to radiation;GO:0048535//lymph node development;GO:0030316//osteoclast differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0002548//monocyte chemotaxis;GO:0071812//positive regulation of fever generation by positive regulation of prostaglandin secretion;GO:0060086//circadian temperature homeostasis;GO:0070555//response to interleukin-1;GO:0007165//signal transduction,GO:0046872//metal ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005031//tumor necrosis factor-activated receptor activity;GO:0019955//cytokine binding;GO:0004872//receptor activity,K05147//Osteoclast differentiation;NF-kappa B signaling pathway;Rheumatoid arthritis;Cytokine-cytokine receptor interaction
8793,0,0,0,0,1,0,0,115,2,5,0,349,"TNFRSF10D;tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain",GO:0016021//integral component of membrane,GO:0007165//signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0006915//apoptotic process,GO:0045569//TRAIL binding;GO:0004888//transmembrane signaling receptor activity,K04722//Cytokine-cytokine receptor interaction;Apoptosis;Natural killer cell mediated cytotoxicity;Influenza A;p53 signaling pathway;Measles
8794,0,0,0,0,0,0,0,0,26,0,0,0,"TNFRSF10C;tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain",GO:0031225//anchored component of membrane;GO:0005887//integral component of plasma membrane,GO:0006915//apoptotic process;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0045569//TRAIL binding,K04722//Cytokine-cytokine receptor interaction;Natural killer cell mediated cytotoxicity;Apoptosis;Influenza A;p53 signaling pathway;Measles
8795,0,13,1,20,27,0,46,0,44,0,2,0,"TNFRSF10B;tumor necrosis factor receptor superfamily, member 10b",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007166//cell surface receptor signaling pathway;GO:0006915//apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0097190//apoptotic signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0042981//regulation of apoptotic process;GO:0034976//response to endoplasmic reticulum stress;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0005515//protein binding;GO:0045569//TRAIL binding;GO:0004872//receptor activity,K04722//p53 signaling pathway;Measles;Influenza A;Apoptosis;Natural killer cell mediated cytotoxicity;Cytokine-cytokine receptor interaction
8796,108,0,0,0,0,57,0,71,13,0,13,1,SCEL;sciellin,GO:0005737//cytoplasm;GO:0001533//cornified envelope;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0009790//embryo development;GO:0008544//epidermis development;GO:0030216//keratinocyte differentiation,GO:0008270//zinc ion binding;GO:0005515//protein binding,K06084//Adherens junction
8797,0,0,43,0,12,10,0,1,26,75,19,0,"TNFRSF10A;tumor necrosis factor receptor superfamily, member 10a",GO:0016021//integral component of membrane,GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0071260//cellular response to mechanical stimulus;GO:0007165//signal transduction;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0006915//apoptotic process,GO:0045569//TRAIL binding;GO:0004872//receptor activity;GO:0005035//death receptor activity;GO:0002020//protease binding;GO:0005515//protein binding;GO:0008134//transcription factor binding,K04722//Measles;p53 signaling pathway;Influenza A;Natural killer cell mediated cytotoxicity;Apoptosis;Cytokine-cytokine receptor interaction
8798,0,0,23,20,1,0,0,0,30,0,4,0,DYRK4;dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4,GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle,GO:0018108//peptidyl-tyrosine phosphorylation,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding,-
8799,0,67,0,0,17,0,0,0,9,0,4,0,PEX11B;peroxisomal biogenesis factor 11 beta,GO:0005778//peroxisomal membrane;GO:0070062//extracellular vesicular exosome;GO:0005779//integral component of peroxisomal membrane;GO:0005739//mitochondrion;GO:0016020//membrane;GO:0043234//protein complex;GO:0005777//peroxisome,GO:0007031//peroxisome organization;GO:0007165//signal transduction;GO:0044375//regulation of peroxisome size;GO:0016559//peroxisome fission;GO:0051260//protein homooligomerization,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K13352//Peroxisome
88,1,0,0,0,0,55,19,1,67,0,14,161,"ACTN2;actinin, alpha 2",GO:0031143//pseudopodium;GO:0031093//platelet alpha granule lumen;GO:0005829//cytosol;GO:0005925//focal adhesion;GO:0005884//actin filament;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0030175//filopodium;GO:0030018//Z disc;GO:0043197//dendritic spine;GO:0005856//cytoskeleton,GO:0043267//negative regulation of potassium ion transport;GO:0042391//regulation of membrane potential;GO:2000009//negative regulation of protein localization to cell surface;GO:0051289//protein homotetramerization;GO:2000273//positive regulation of receptor activity;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:0007596//blood coagulation;GO:0043268//positive regulation of potassium ion transport;GO:2001141//regulation of RNA biosynthetic process;GO:0007268//synaptic transmission;GO:0002576//platelet degranulation;GO:0007155//cell adhesion;GO:0048041//focal adhesion assembly;GO:0030049//muscle filament sliding;GO:0042981//regulation of apoptotic process;GO:0030035//microspike assembly;GO:0030168//platelet activation;GO:1901018//positive regulation of potassium ion transmembrane transporter activity,GO:0030375//thyroid hormone receptor coactivator activity;GO:0008307//structural constituent of muscle;GO:0046983//protein dimerization activity;GO:0051373//FATZ binding;GO:0042802//identical protein binding;GO:0031432//titin binding;GO:0051015//actin filament binding;GO:0030274//LIM domain binding;GO:0008092//cytoskeletal protein binding;GO:0070080//titin Z domain binding;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0044325//ion channel binding;GO:0005509//calcium ion binding,K05699//Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Adherens junction;Focal adhesion;Amoebiasis;Systemic lupus erythematosus;Regulation of actin cytoskeleton
8800,0,42,0,25,93,0,0,0,19,0,9,0,PEX11A;peroxisomal biogenesis factor 11 alpha,GO:0005777//peroxisome;GO:0043234//protein complex;GO:0005778//peroxisomal membrane;GO:0005779//integral component of peroxisomal membrane,GO:0044375//regulation of peroxisome size;GO:0016557//peroxisome membrane biogenesis;GO:0007031//peroxisome organization;GO:0050873//brown fat cell differentiation;GO:0044281//small molecule metabolic process;GO:0016559//peroxisome fission;GO:0007165//signal transduction;GO:0044255//cellular lipid metabolic process,GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K13351//Peroxisome
8801,0,0,1,94,135,7,36,0,53,65,0,0,"SUCLG2;succinate-CoA ligase, GDP-forming, beta subunit",GO:0045244//succinate-CoA ligase complex (GDP-forming);GO:0005759//mitochondrial matrix;GO:0005739//mitochondrion;GO:0005886//plasma membrane,GO:0006105//succinate metabolic process;GO:0006104//succinyl-CoA metabolic process;GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle,GO:0019003//GDP binding;GO:0046982//protein heterodimerization activity;GO:0005524//ATP binding;GO:0004776//succinate-CoA ligase (GDP-forming) activity;GO:0005525//GTP binding,K01900//Propanoate metabolism;Metabolic pathways;Citrate cycle (TCA cycle);Biosynthesis of secondary metabolites
8802,0,0,0,1,9,0,0,0,16,0,9,0,"SUCLG1;succinate-CoA ligase, alpha subunit",GO:0070062//extracellular vesicular exosome;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005759//mitochondrial matrix;GO:0045244//succinate-CoA ligase complex (GDP-forming),GO:0044281//small molecule metabolic process;GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006105//succinate metabolic process;GO:0006104//succinyl-CoA metabolic process,GO:0046982//protein heterodimerization activity;GO:0044822//poly(A) RNA binding;GO:0004775//succinate-CoA ligase (ADP-forming) activity;GO:0003878//ATP citrate synthase activity;GO:0004776//succinate-CoA ligase (GDP-forming) activity;GO:0019003//GDP binding;GO:0048037//cofactor binding;GO:0005525//GTP binding,K01899//Propanoate metabolism;Metabolic pathways;Citrate cycle (TCA cycle);Biosynthesis of secondary metabolites
8803,95,1,0,2,8,36,0,0,14,0,0,0,"SUCLA2;succinate-CoA ligase, ADP-forming, beta subunit",GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0005759//mitochondrial matrix,GO:0044237//cellular metabolic process;GO:0006099//tricarboxylic acid cycle;GO:0006781//succinyl-CoA pathway;GO:0044281//small molecule metabolic process;GO:0006104//succinyl-CoA metabolic process;GO:0006105//succinate metabolic process,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004775//succinate-CoA ligase (ADP-forming) activity,K01900//Metabolic pathways;Citrate cycle (TCA cycle);Propanoate metabolism;Biosynthesis of secondary metabolites
8804,0,0,0,1,11,0,0,0,0,150,4,0,CREG1;cellular repressor of E1A-stimulated genes 1,GO:0070062//extracellular vesicular exosome;GO:0005667//transcription factor complex,GO:0055114//oxidation-reduction process;GO:0008283//cell proliferation;GO:0040008//regulation of growth;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007275//multicellular organismal development,GO:0010181//FMN binding;GO:0003714//transcription corepressor activity;GO:0008134//transcription factor binding;GO:0016491//oxidoreductase activity,K06453//T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chagas disease (American trypanosomiasis)
8805,3,1,0,3,123,0,9,0,43,0,9,0,TRIM24;tripartite motif containing 24,GO:0005719//nuclear euchromatin;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005726//perichromatin fibrils,"GO:0008285//negative regulation of cell proliferation;GO:0031647//regulation of protein stability;GO:0016567//protein ubiquitination;GO:0043434//response to peptide hormone;GO:0045892//negative regulation of transcription, DNA-templated;GO:1901796//regulation of signal transduction by p53 class mediator;GO:0006366//transcription from RNA polymerase II promoter;GO:0071391//cellular response to estrogen stimulus;GO:0046777//protein autophosphorylation;GO:0030163//protein catabolic process;GO:0070562//regulation of vitamin D receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0055074//calcium ion homeostasis;GO:0042981//regulation of apoptotic process",GO:0016922//ligand-dependent nuclear receptor binding;GO:0043565//sequence-specific DNA binding;GO:0016874//ligase activity;GO:0034056//estrogen response element binding;GO:0004672//protein kinase activity;GO:0035064//methylated histone binding;GO:0002039//p53 binding;GO:0003682//chromatin binding;GO:0070577//lysine-acetylated histone binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding;GO:0005102//receptor binding,-
8807,78,0,0,0,0,5,29,0,19,0,0,0,IL18RAP;interleukin 18 receptor accessory protein,GO:0016021//integral component of membrane,GO:0006954//inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0006955//immune response,GO:0004872//receptor activity,K05174//Cytokine-cytokine receptor interaction
8808,0,0,0,0,0,0,87,3,0,0,0,318,IL1RL2;interleukin 1 receptor-like 2,GO:0005887//integral component of plasma membrane,GO:0007165//signal transduction;GO:0019221//cytokine-mediated signaling pathway;GO:0045582//positive regulation of T cell differentiation;GO:0050727//regulation of inflammatory response;GO:0006968//cellular defense response;GO:0070498//interleukin-1-mediated signaling pathway;GO:0032755//positive regulation of interleukin-6 production,"GO:0004908//interleukin-1 receptor activity;GO:0004909//interleukin-1, Type I, activating receptor activity",-
8809,0,0,0,0,0,0,51,0,40,100,0,0,IL18R1;interleukin 18 receptor 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0032729//positive regulation of interferon-gamma production;GO:0035655//interleukin-18-mediated signaling pathway;GO:0006955//immune response;GO:0045063//T-helper 1 cell differentiation;GO:0030101//natural killer cell activation;GO:0007165//signal transduction;GO:0042346//positive regulation of NF-kappaB import into nucleus,GO:0004908//interleukin-1 receptor activity;GO:0004872//receptor activity;GO:0042008//interleukin-18 receptor activity,K05173//Cytokine-cytokine receptor interaction
881,0,0,0,0,0,0,48,0,14,0,11,0,CCIN;calicin,GO:0005634//nucleus;GO:0033150//cytoskeletal calyx,GO:0030154//cell differentiation;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development,-,-
8811,0,0,0,0,0,0,0,1,16,158,0,0,GALR2;galanin receptor 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007611//learning or memory;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0031175//neuron projection development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007586//digestion;GO:0007275//multicellular organismal development;GO:0007268//synaptic transmission;GO:0006936//muscle contraction;GO:0007194//negative regulation of adenylate cyclase activity;GO:0007218//neuropeptide signaling pathway;GO:0007631//feeding behavior;GO:0007166//cell surface receptor signaling pathway;GO:1902608//positive regulation of large conductance calcium-activated potassium channel activity,GO:0004966//galanin receptor activity;GO:0005515//protein binding;GO:0017046//peptide hormone binding,K04231//Neuroactive ligand-receptor interaction
8812,0,21,0,12,45,35,0,0,28,0,8,1,CCNK;cyclin K,GO:0005634//nucleus;GO:0002944//cyclin K-CDK12 complex;GO:0002945//cyclin K-CDK13 complex,"GO:0001701//in utero embryonic development;GO:0006974//cellular response to DNA damage stimulus;GO:0006355//regulation of transcription, DNA-templated;GO:0007067//mitotic nuclear division;GO:0006366//transcription from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0071157//negative regulation of cell cycle arrest;GO:0006468//protein phosphorylation",GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,K15188//Transcriptional misregulation in cancer
8813,0,0,20,23,80,0,0,0,0,0,18,0,"DPM1;dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit",GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0033185//dolichol-phosphate-mannose synthase complex;GO:0005783//endoplasmic reticulum;GO:0016020//membrane,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0019673//GDP-mannose metabolic process;GO:0019348//dolichol metabolic process;GO:0035269//protein O-linked mannosylation;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0043687//post-translational protein modification;GO:0006506//GPI anchor biosynthetic process,GO:0004582//dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0004169//dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0005515//protein binding;GO:0005537//mannose binding;GO:0043178//alcohol binding,K00721//Metabolic pathways;N-Glycan biosynthesis
8814,0,0,125,91,38,29,0,122,0,0,32,0,CDKL1;cyclin-dependent kinase-like 1 (CDC2-related kinase),GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0007507//heart development,GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,-
8815,0,106,49,41,183,0,0,0,0,0,164,0,BANF1;barrier to autointegration factor 1,GO:0070062//extracellular vesicular exosome;GO:0005694//chromosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0007084//mitotic nuclear envelope reassembly;GO:0009615//response to virus;GO:0000278//mitotic cell cycle;GO:0015074//DNA integration;GO:0075713//establishment of integrated proviral latency;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process,GO:0005515//protein binding;GO:0003677//DNA binding,-
8816,0,50,0,25,25,4,47,0,20,89,0,0,DCAF5;DDB1 and CUL4 associated factor 5,GO:0080008//Cul4-RING E3 ubiquitin ligase complex;GO:0005739//mitochondrion,GO:0016567//protein ubiquitination,-,-
8817,0,0,0,0,0,0,0,0,6,0,0,0,FGF18;fibroblast growth factor 18,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005730//nucleolus,GO:0008286//insulin receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0002063//chondrocyte development;GO:0007399//nervous system development;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0030324//lung development;GO:0007165//signal transduction;GO:0030949//positive regulation of vascular endothelial growth factor receptor signaling pathway;GO:0001958//endochondral ossification;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0001957//intramembranous ossification;GO:0009653//anatomical structure morphogenesis;GO:0001525//angiogenesis;GO:0032332//positive regulation of chondrocyte differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway,GO:0005105//type 1 fibroblast growth factor receptor binding;GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008083//growth factor activity,K04358//MAPK signaling pathway;Pathways in cancer;Melanoma;Regulation of actin cytoskeleton
8819,0,0,0,0,0,0,0,0,1,0,21,0,"SAP30;Sin3A-associated protein, 30kDa",GO:0000118//histone deacetylase complex,"GO:0006351//transcription, DNA-templated;GO:0035914//skeletal muscle cell differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0003714//transcription corepressor activity,-
8820,0,0,0,0,0,36,0,0,0,0,0,0,HESX1;HESX homeobox 1,GO:0005634//nucleus,"GO:0048853//forebrain morphogenesis;GO:0007420//brain development;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043584//nose development;GO:0030916//otic vesicle formation",GO:0008022//protein C-terminus binding;GO:0003682//chromatin binding;GO:0047485//protein N-terminus binding;GO:0003677//DNA binding;GO:0005515//protein binding;GO:0043565//sequence-specific DNA binding,-
8821,0,40,27,31,157,24,43,76,0,0,0,0,"INPP4B;inositol polyphosphate-4-phosphatase, type II, 105kDa",GO:0005794//Golgi apparatus;GO:0005829//cytosol,GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0046822//regulation of nucleocytoplasmic transport;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0006874//cellular calcium ion homeostasis;GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0051896//regulation of protein kinase B signaling;GO:0043647//inositol phosphate metabolic process;GO:0046850//regulation of bone remodeling;GO:0045671//negative regulation of osteoclast differentiation;GO:0016311//dephosphorylation,"GO:0034597//phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity;GO:0034594//phosphatidylinositol trisphosphate phosphatase activity;GO:0008289//lipid binding;GO:0016316//phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity",K01109//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
8822,0,0,0,0,0,0,0,0,17,0,0,0,FGF17;fibroblast growth factor 17,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007267//cell-cell signaling;GO:0008286//insulin receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007399//nervous system development,GO:0005111//type 2 fibroblast growth factor receptor binding;GO:0008083//growth factor activity;GO:0005105//type 1 fibroblast growth factor receptor binding,K04358//Pathways in cancer;MAPK signaling pathway;Regulation of actin cytoskeleton;Melanoma
8824,1,2,0,14,34,24,66,0,37,0,1,0,CES2;carboxylesterase 2,GO:0005783//endoplasmic reticulum;GO:0005788//endoplasmic reticulum lumen,GO:0009056//catabolic process,GO:0047374//methylumbelliferyl-acetate deacetylase activity;GO:0052689//carboxylic ester hydrolase activity,K03927//Drug metabolism - other enzymes
8825,85,0,0,6,0,8,0,0,61,265,0,0,LIN7A;lin-7 homolog A (C. elegans),GO:0045211//postsynaptic membrane;GO:0016323//basolateral plasma membrane;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0005923//tight junction;GO:0014069//postsynaptic density,GO:0048489//synaptic vesicle transport;GO:0007269//neurotransmitter secretion;GO:0048839//inner ear development;GO:0015031//protein transport;GO:0006461//protein complex assembly;GO:0006887//exocytosis,GO:0005515//protein binding;GO:0097016//L27 domain binding;GO:0030165//PDZ domain binding,-
8826,18,41,0,54,185,0,2,0,50,36,0,0,IQGAP1;IQ motif containing GTPase activating protein 1,GO:0005925//focal adhesion;GO:0030496//midbody;GO:0005730//nucleolus;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005884//actin filament;GO:0030054//cell junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0036057//slit diaphragm;GO:0031252//cell leading edge;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0016328//lateral plasma membrane,GO:0071364//cellular response to epidermal growth factor stimulus;GO:0072015//glomerular visceral epithelial cell development;GO:0050796//regulation of insulin secretion;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0071277//cellular response to calcium ion;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0044281//small molecule metabolic process;GO:0001817//regulation of cytokine production;GO:0043086//negative regulation of catalytic activity;GO:0006112//energy reserve metabolic process;GO:0032320//positive regulation of Ras GTPase activity;GO:0035305//negative regulation of dephosphorylation;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045860//positive regulation of protein kinase activity;GO:0007165//signal transduction,"GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0005099//Ras GTPase activator activity;GO:0005516//calmodulin binding;GO:0032403//protein complex binding;GO:0019903//protein phosphatase binding;GO:0048365//Rac GTPase binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005515//protein binding;GO:0005095//GTPase inhibitor activity;GO:0005509//calcium ion binding;GO:0005096//GTPase activator activity",K05767//Adherens junction;Regulation of actin cytoskeleton
8828,23,0,0,0,0,43,19,55,32,0,2,0,NRP2;neuropilin 2,GO:0005886//plasma membrane;GO:0030424//axon;GO:0005576//extracellular region;GO:0002116//semaphorin receptor complex;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0001938//positive regulation of endothelial cell proliferation;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0007411//axon guidance;GO:0001525//angiogenesis;GO:0007507//heart development;GO:0097491//sympathetic neuron projection guidance;GO:0061549//sympathetic ganglion development;GO:0050919//negative chemotaxis;GO:0021675//nerve development;GO:0007155//cell adhesion;GO:0097490//sympathetic neuron projection extension;GO:0048846//axon extension involved in axon guidance;GO:0001755//neural crest cell migration;GO:0038084//vascular endothelial growth factor signaling pathway,GO:0046872//metal ion binding;GO:0008201//heparin binding;GO:0017154//semaphorin receptor activity;GO:0019955//cytokine binding;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0004872//receptor activity;GO:0019838//growth factor binding,-
8829,2,0,0,1,1,0,4,0,34,128,17,0,NRP1;neuropilin 1,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0030424//axon;GO:0005925//focal adhesion;GO:0002116//semaphorin receptor complex;GO:0097443//sorting endosome;GO:0043235//receptor complex;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005883//neurofilament;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0031410//cytoplasmic vesicle;GO:0043025//neuronal cell body;GO:0030426//growth cone,GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0010595//positive regulation of endothelial cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:1902285//semaphorin-plexin signaling pathway involved in neuron projection guidance;GO:0009887//organ morphogenesis;GO:0050918//positive chemotaxis;GO:0060627//regulation of vesicle-mediated transport;GO:0002040//sprouting angiogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0014911//positive regulation of smooth muscle cell migration;GO:0001525//angiogenesis;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0031290//retinal ganglion cell axon guidance;GO:0001764//neuron migration;GO:0021675//nerve development;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0021612//facial nerve structural organization;GO:0007155//cell adhesion;GO:0097490//sympathetic neuron projection extension;GO:0060301//positive regulation of cytokine activity;GO:0097102//endothelial tip cell fate specification;GO:0035767//endothelial cell chemotaxis;GO:0043524//negative regulation of neuron apoptotic process;GO:0060982//coronary artery morphogenesis;GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0048844//artery morphogenesis;GO:0001569//patterning of blood vessels;GO:0009611//response to wounding;GO:0016358//dendrite development;GO:0021785//branchiomotor neuron axon guidance;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0060666//dichotomous subdivision of terminal units involved in salivary gland branching;GO:0038190//VEGF-activated neuropilin signaling pathway;GO:0071526//semaphorin-plexin signaling pathway;GO:0001938//positive regulation of endothelial cell proliferation;GO:0007411//axon guidance;GO:0061441//renal artery morphogenesis;GO:0007267//cell-cell signaling;GO:0007413//axonal fasciculation;GO:1902946//protein localization to early endosome;GO:0097491//sympathetic neuron projection guidance;GO:0061549//sympathetic ganglion development;GO:1902336//positive regulation of retinal ganglion cell axon guidance;GO:0071679//commissural neuron axon guidance;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0048846//axon extension involved in axon guidance;GO:0060978//angiogenesis involved in coronary vascular morphogenesis;GO:0060385//axonogenesis involved in innervation;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0007165//signal transduction,GO:0015026//coreceptor activity;GO:0005021//vascular endothelial growth factor-activated receptor activity;GO:0019838//growth factor binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0008201//heparin binding;GO:0038085//vascular endothelial growth factor binding;GO:0019955//cytokine binding;GO:0017154//semaphorin receptor activity,K06724//HTLV-I infection;Axon guidance
883,0,1,0,1,2,20,0,0,60,0,14,0,"CCBL1;cysteine conjugate-beta lyase, cytoplasmic",GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0008652//cellular amino acid biosynthetic process;GO:0006559//L-phenylalanine catabolic process;GO:0097053//L-kynurenine catabolic process;GO:0044281//small molecule metabolic process;GO:0006569//tryptophan catabolic process;GO:0034641//cellular nitrogen compound metabolic process,GO:0047316//glutamine-phenylpyruvate transaminase activity;GO:0008483//transaminase activity;GO:0036141//L-phenylalanine-oxaloacetate transaminase activity;GO:0016212//kynurenine-oxoglutarate transaminase activity;GO:0042803//protein homodimerization activity;GO:0047312//L-phenylalanine:pyruvate aminotransferase activity;GO:0030170//pyridoxal phosphate binding;GO:0047804//cysteine-S-conjugate beta-lyase activity;GO:0047945//L-glutamine:pyruvate aminotransferase activity,K00816//Selenocompound metabolism;Tryptophan metabolism;Metabolic pathways
8831,35,0,0,0,0,9,23,105,11,0,6,1,SYNGAP1;synaptic Ras GTPase activating protein 1,GO:0043198//dendritic shaft;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane;GO:0005737//cytoplasm,GO:0043524//negative regulation of neuron apoptotic process;GO:0043113//receptor clustering;GO:0008542//visual learning;GO:0007265//Ras protein signal transduction;GO:0016358//dendrite development;GO:0046580//negative regulation of Ras protein signal transduction;GO:0048167//regulation of synaptic plasticity;GO:0048169//regulation of long-term neuronal synaptic plasticity;GO:0032320//positive regulation of Ras GTPase activity;GO:0050803//regulation of synapse structure and activity;GO:0007389//pattern specification process;GO:0043408//regulation of MAPK cascade;GO:0032851//positive regulation of Rab GTPase activity;GO:0050771//negative regulation of axonogenesis,GO:0005099//Ras GTPase activator activity;GO:0005097//Rab GTPase activator activity;GO:0017124//SH3 domain binding,K04352//MAPK signaling pathway;Axon guidance
8832,0,0,0,0,0,56,0,65,72,107,0,255,CD84;CD84 molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0050900//leukocyte migration;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0006952//defense response;GO:0007596//blood coagulation,GO:0004872//receptor activity;GO:0005515//protein binding,-
8833,15,60,1,26,45,0,20,0,17,0,0,0,GMPS;guanine monphosphate synthase,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0009168//purine ribonucleoside monophosphate biosynthetic process;GO:0006177//GMP biosynthetic process;GO:0006144//purine nucleobase metabolic process;GO:0044281//small molecule metabolic process;GO:0009113//purine nucleobase biosynthetic process;GO:0006541//glutamine metabolic process,GO:0005524//ATP binding;GO:0016462//pyrophosphatase activity;GO:0003921//GMP synthase activity;GO:0003922//GMP synthase (glutamine-hydrolyzing) activity,K01951//Metabolic pathways;Drug metabolism - other enzymes;Purine metabolism
8834,1,66,0,1,9,0,0,0,3,0,0,0,TMEM11;transmembrane protein 11,GO:0005887//integral component of plasma membrane;GO:0031305//integral component of mitochondrial inner membrane,GO:0007005//mitochondrion organization,GO:0005515//protein binding,-
8835,0,162,68,36,118,0,0,506,2,0,176,0,SOCS2;suppressor of cytokine signaling 2,GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0043066//negative regulation of apoptotic process;GO:0016567//protein ubiquitination;GO:0009966//regulation of signal transduction;GO:0046426//negative regulation of JAK-STAT cascade;GO:0060396//growth hormone receptor signaling pathway;GO:0032355//response to estradiol;GO:0007259//JAK-STAT cascade;GO:0009967//positive regulation of signal transduction;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0001558//regulation of cell growth;GO:0032870//cellular response to hormone stimulus,GO:0005515//protein binding;GO:0008269//JAK pathway signal transduction adaptor activity;GO:0005131//growth hormone receptor binding;GO:0005159//insulin-like growth factor receptor binding;GO:0005070//SH3/SH2 adaptor activity,K04695//Jak-STAT signaling pathway;Insulin signaling pathway;Type II diabetes mellitus
8836,92,0,0,0,0,0,0,0,21,0,0,0,"GGH;gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)",GO:0005634//nucleus;GO:0005764//lysosome;GO:0070062//extracellular vesicular exosome;GO:0042470//melanosome;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0042493//response to drug;GO:0010043//response to zinc ion;GO:0045471//response to ethanol;GO:0006541//glutamine metabolic process;GO:0032868//response to insulin;GO:0006508//proteolysis,GO:0008242//omega peptidase activity;GO:0034722//gamma-glutamyl-peptidase activity,K01307//Folate biosynthesis
8837,63,61,1,16,196,51,0,0,53,0,8,0,CFLAR;CASP8 and FADD-like apoptosis regulator,GO:0031265//CD95 death-inducing signaling complex;GO:0005829//cytosol;GO:0097342//ripoptosome;GO:0005737//cytoplasm;GO:0031264//death-inducing signaling complex,GO:0014842//regulation of satellite cell proliferation;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0014866//skeletal myofibril assembly;GO:0043066//negative regulation of apoptotic process;GO:2001239//regulation of extrinsic apoptotic signaling pathway in absence of ligand;GO:0043403//skeletal muscle tissue regeneration;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0043085//positive regulation of catalytic activity;GO:0006915//apoptotic process;GO:0007519//skeletal muscle tissue development;GO:1901740//negative regulation of myoblast fusion;GO:0006508//proteolysis;GO:0097190//apoptotic signaling pathway;GO:0060544//regulation of necroptotic process;GO:0016032//viral process;GO:0014732//skeletal muscle atrophy,GO:0002020//protease binding;GO:0008047//enzyme activator activity;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0035877//death effector domain binding,K04724//NF-kappa B signaling pathway;Chagas disease (American trypanosomiasis);Apoptosis
8839,0,0,0,0,0,0,0,0,11,157,0,0,WISP2;WNT1 inducible signaling pathway protein 2,GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007267//cell-cell signaling;GO:0001558//regulation of cell growth;GO:0007165//signal transduction;GO:0007155//cell adhesion,GO:0005520//insulin-like growth factor binding,-
8840,0,10,104,0,3,0,19,63,95,0,12,1,WISP1;WNT1 inducible signaling pathway protein 1,GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0016055//Wnt signaling pathway;GO:0007155//cell adhesion;GO:0001558//regulation of cell growth;GO:0007267//cell-cell signaling,GO:0005520//insulin-like growth factor binding,-
8841,118,26,1,1,42,0,19,0,37,0,0,0,HDAC3;histone deacetylase 3,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0005654//nucleoplasm;GO:0017053//transcriptional repressor complex;GO:0000118//histone deacetylase complex,"GO:0051225//spindle assembly;GO:0040014//regulation of multicellular organism growth;GO:0045786//negative regulation of cell cycle;GO:0007219//Notch signaling pathway;GO:0007346//regulation of mitotic cell cycle;GO:0016568//chromatin modification;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070933//histone H4 deacetylation;GO:0006476//protein deacetylation;GO:0046329//negative regulation of JNK cascade;GO:0010832//negative regulation of myotube differentiation;GO:0044255//cellular lipid metabolic process;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0070932//histone H3 deacetylation;GO:0044281//small molecule metabolic process;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043066//negative regulation of apoptotic process",GO:0004407//histone deacetylase activity;GO:0031490//chromatin DNA binding;GO:0030332//cyclin binding;GO:0042826//histone deacetylase binding;GO:0003714//transcription corepressor activity;GO:0033558//protein deacetylase activity;GO:0003682//chromatin binding;GO:0019899//enzyme binding;GO:0008134//transcription factor binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0005515//protein binding;GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific),K11404//Alcoholism
8842,0,0,0,0,0,17,11,0,42,0,0,0,PROM1;prominin 1,GO:0031528//microvillus membrane;GO:0005615//extracellular space;GO:0032420//stereocilium;GO:0005903//brush border;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0009986//cell surface;GO:0042622//photoreceptor outer segment membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0001750//photoreceptor outer segment,GO:0072139//glomerular parietal epithelial cell differentiation;GO:0060219//camera-type eye photoreceptor cell differentiation;GO:0010842//retina layer formation;GO:0072112//glomerular visceral epithelial cell differentiation;GO:0060042//retina morphogenesis in camera-type eye;GO:2000768//positive regulation of nephron tubule epithelial cell differentiation;GO:0045494//photoreceptor cell maintenance,GO:0005515//protein binding;GO:0045296//cadherin binding;GO:0042805//actinin binding,K06532//Transcriptional misregulation in cancer
8843,0,0,0,0,0,0,0,0,9,0,0,130,HCAR3;hydroxycarboxylic acid receptor 3,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
8844,0,0,0,0,0,0,45,0,33,0,7,0,KSR1;kinase suppressor of ras 1,GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007265//Ras protein signal transduction;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004672//protein kinase activity,K14958//Tuberculosis
88455,0,6,26,30,145,1,0,0,79,0,38,0,ANKRD13A;ankyrin repeat domain 13A,GO:0005886//plasma membrane;GO:0005770//late endosome,-,-,-
8846,0,0,0,7,23,12,25,0,0,0,0,0,"ALKBH1;alkB, alkylation repair homolog 1 (E. coli)",GO:0005739//mitochondrion;GO:0005719//nuclear euchromatin,"GO:0048589//developmental growth;GO:0080111//DNA demethylation;GO:0006281//DNA repair;GO:0031175//neuron projection development;GO:0042245//RNA repair;GO:0050918//positive chemotaxis;GO:0001701//in utero embryonic development;GO:0043524//negative regulation of neuron apoptotic process;GO:0070989//oxidative demethylation;GO:0001890//placenta development;GO:0006307//DNA dealkylation involved in DNA repair;GO:0001764//neuron migration;GO:0000737//DNA catabolic process, endonucleolytic",GO:0042056//chemoattractant activity;GO:0008198//ferrous iron binding;GO:0003906//DNA-(apurinic or apyrimidinic site) lyase activity;GO:0070579//methylcytosine dioxygenase activity,-
8848,55,85,1,101,341,53,9,0,18,0,39,0,"TSC22D1;TSC22 domain family, member 1",GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0043066//negative regulation of apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding,-
885,0,34,62,5,17,0,2,0,0,0,38,0,CCK;cholecystokinin,GO:0043195//terminal bouton;GO:0005615//extracellular space;GO:0030424//axon;GO:0043194//axon initial segment;GO:0043204//perikaryon;GO:0043203//axon hillock;GO:0005576//extracellular region;GO:0030425//dendrite,GO:0051901//positive regulation of mitochondrial depolarization;GO:0043065//positive regulation of apoptotic process;GO:0032099//negative regulation of appetite;GO:0001764//neuron migration;GO:0042755//eating behavior;GO:0051930//regulation of sensory perception of pain;GO:0007409//axonogenesis;GO:0007165//signal transduction;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0001662//behavioral fear response;GO:0032461//positive regulation of protein oligomerization;GO:0008284//positive regulation of cell proliferation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0001836//release of cytochrome c from mitochondria;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0005179//hormone activity;GO:0005184//neuropeptide hormone activity;GO:0005515//protein binding,-
8850,182,12,0,63,73,0,0,0,10,0,8,0,KAT2B;K(lysine) acetyltransferase 2B,GO:0031674//I band;GO:0000125//PCAF complex;GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex;GO:0005634//nucleus;GO:0031672//A band;GO:0005654//nucleoplasm;GO:0042641//actomyosin;GO:0000776//kinetochore,GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048511//rhythmic process;GO:0043966//histone H3 acetylation;GO:0007219//Notch signaling pathway;GO:0007050//cell cycle arrest;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006338//chromatin remodeling;GO:0018394//peptidyl-lysine acetylation;GO:0006473//protein acetylation;GO:0045722//positive regulation of gluconeogenesis;GO:0006360//transcription from RNA polymerase I promoter;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0010835//regulation of protein ADP-ribosylation;GO:0018076//N-terminal peptidyl-lysine acetylation;GO:0018393//internal peptidyl-lysine acetylation;GO:0032869//cellular response to insulin stimulus;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006325//chromatin organization;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression,"GO:0019901//protein kinase binding;GO:0042826//histone deacetylase binding;GO:0016407//acetyltransferase activity;GO:0004402//histone acetyltransferase activity;GO:0004861//cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0032403//protein complex binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0008134//transcription factor binding;GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0003712//transcription cofactor activity",K06062//HTLV-I infection;Notch signaling pathway
8851,0,0,0,0,1,7,11,0,23,0,0,0,"CDK5R1;cyclin-dependent kinase 5, regulatory subunit 1 (p35)",GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0031594//neuromuscular junction;GO:0016020//membrane;GO:0016533//cyclin-dependent protein kinase 5 holoenzyme complex;GO:0043025//neuronal cell body;GO:0030426//growth cone;GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0014069//postsynaptic density;GO:0030424//axon;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0043292//contractile fiber,"GO:0043525//positive regulation of neuron apoptotic process;GO:0061001//regulation of dendritic spine morphogenesis;GO:0008283//cell proliferation;GO:0007411//axon guidance;GO:0007420//brain development;GO:0035235//ionotropic glutamate receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0090314//positive regulation of protein targeting to membrane;GO:0045664//regulation of neuron differentiation;GO:0007413//axonal fasciculation;GO:0021549//cerebellum development;GO:0009790//embryo development;GO:0007158//neuron cell-cell adhesion;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0030517//negative regulation of axon extension;GO:0021766//hippocampus development;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0048013//ephrin receptor signaling pathway;GO:0007213//G-protein coupled acetylcholine receptor signaling pathway;GO:0031175//neuron projection development;GO:0021819//layer formation in cerebral cortex;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033136//serine phosphorylation of STAT3 protein;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0001764//neuron migration;GO:0030182//neuron differentiation;GO:0018107//peptidyl-threonine phosphorylation;GO:0021722//superior olivary nucleus maturation;GO:0048511//rhythmic process;GO:0018105//peptidyl-serine phosphorylation",GO:0005515//protein binding;GO:0005509//calcium ion binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0016534//cyclin-dependent protein kinase 5 activator activity;GO:0004672//protein kinase activity;GO:0045296//cadherin binding;GO:0019901//protein kinase binding;GO:0043539//protein serine/threonine kinase activator activity;GO:0016301//kinase activity;GO:0046875//ephrin receptor binding,K11716//Cocaine addiction;Alzheimer's disease
8852,0,11,0,3,16,0,0,58,0,0,2,0,AKAP4;A kinase (PRKA) anchor protein 4,GO:0005856//cytoskeleton;GO:0005952//cAMP-dependent protein kinase complex;GO:0097228//sperm principal piece;GO:0030018//Z disc;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0031514//motile cilium;GO:0035686//sperm fibrous sheath,GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0030317//sperm motility;GO:0007338//single fertilization;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0007165//signal transduction;GO:0006928//cellular component movement,GO:0051018//protein kinase A binding,-
8853,0,0,0,4,24,0,0,78,52,86,0,0,"ASAP2;ArfGAP with SH3 domain, ankyrin repeat and PH domain 2",GO:0005886//plasma membrane;GO:0032580//Golgi cisterna membrane,GO:0043085//positive regulation of catalytic activity;GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity,GO:0008047//enzyme activator activity;GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding,K12488//Endocytosis;Fc gamma R-mediated phagocytosis
8854,0,0,0,0,0,16,24,0,1,0,0,0,"ALDH1A2;aldehyde dehydrogenase 1 family, member A2",GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0016331//morphogenesis of embryonic epithelium;GO:0048738//cardiac muscle tissue development;GO:0031016//pancreas development;GO:0042904//9-cis-retinoic acid biosynthetic process;GO:0021983//pituitary gland development;GO:0014032//neural crest cell development;GO:0030324//lung development;GO:0034097//response to cytokine;GO:0055114//oxidation-reduction process;GO:0030182//neuron differentiation;GO:0048566//embryonic digestive tract development;GO:0031076//embryonic camera-type eye development;GO:0043065//positive regulation of apoptotic process;GO:0021915//neural tube development;GO:0035799//ureter maturation;GO:0001936//regulation of endothelial cell proliferation;GO:0010628//positive regulation of gene expression;GO:0008285//negative regulation of cell proliferation;GO:0060324//face development;GO:0048384//retinoic acid receptor signaling pathway;GO:0008284//positive regulation of cell proliferation;GO:0001889//liver development;GO:0001822//kidney development;GO:0001568//blood vessel development;GO:0007494//midgut development;GO:0071300//cellular response to retinoic acid;GO:0035115//embryonic forelimb morphogenesis;GO:0042574//retinal metabolic process;GO:0030902//hindbrain development;GO:0009952//anterior/posterior pattern specification;GO:0009954//proximal/distal pattern formation;GO:0042572//retinol metabolic process;GO:0006776//vitamin A metabolic process;GO:0042573//retinoic acid metabolic process;GO:0032355//response to estradiol;GO:0003007//heart morphogenesis;GO:0009855//determination of bilateral symmetry;GO:0033189//response to vitamin A,GO:0016918//retinal binding;GO:0001758//retinal dehydrogenase activity;GO:0004028//3-chloroallyl aldehyde dehydrogenase activity,K07249//Metabolic pathways;Retinol metabolism
8856,0,0,0,0,0,0,17,0,33,0,0,0,"NR1I2;nuclear receptor subfamily 1, group I, member 2",GO:0005654//nucleoplasm,"GO:0006805//xenobiotic metabolic process;GO:0007165//signal transduction;GO:0042738//exogenous drug catabolic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030522//intracellular receptor signaling pathway;GO:0046618//drug export;GO:0042908//xenobiotic transport;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0008202//steroid metabolic process;GO:0043401//steroid hormone mediated signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated",GO:0008144//drug binding;GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0003707//steroid hormone receptor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,-
8857,0,0,68,0,10,6,0,125,54,261,26,333,FCGBP;Fc fragment of IgG binding protein,GO:0070062//extracellular vesicular exosome,-,GO:0005515//protein binding,K13908//Salivary secretion
8858,0,0,0,0,0,0,0,0,18,0,6,0,"PROZ;protein Z, vitamin K-dependent plasma glycoprotein",GO:0005796//Golgi lumen;GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen,GO:0007596//blood coagulation;GO:0043687//post-translational protein modification;GO:0017187//peptidyl-glutamic acid carboxylation;GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0005509//calcium ion binding,K01314//Complement and coagulation cascades;K01344//Complement and coagulation cascades
886,0,0,0,0,0,0,0,0,11,0,0,0,CCKAR;cholecystokinin A receptor,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030900//forebrain development;GO:0007584//response to nutrient;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0001764//neuron migration;GO:0007631//feeding behavior;GO:0007409//axonogenesis;GO:0007586//digestion;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0038188//cholecystokinin signaling pathway,GO:0004951//cholecystokinin receptor activity,K04194//Neuroactive ligand-receptor interaction;Calcium signaling pathway;Pancreatic secretion
8861,0,0,0,0,1,13,0,53,20,0,0,84,LDB1;LIM domain binding 1,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0043234//protein complex;GO:0005667//transcription factor complex,"GO:0032784//regulation of DNA-templated transcription, elongation;GO:0021702//cerebellar Purkinje cell differentiation;GO:0006351//transcription, DNA-templated;GO:0060322//head development;GO:0022607//cellular component assembly;GO:0001942//hair follicle development;GO:0010669//epithelial structure maintenance;GO:0006355//regulation of transcription, DNA-templated;GO:0045647//negative regulation of erythrocyte differentiation;GO:0000972//transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery;GO:0006366//transcription from RNA polymerase II promoter;GO:0030182//neuron differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043973//histone H3-K4 acetylation;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0007275//multicellular organismal development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001702//gastrulation with mouth forming second;GO:0016055//Wnt signaling pathway;GO:0009948//anterior/posterior axis specification;GO:0035019//somatic stem cell maintenance;GO:0045785//positive regulation of cell adhesion",GO:0043621//protein self-association;GO:0042803//protein homodimerization activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0030274//LIM domain binding;GO:0001158//enhancer sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0003714//transcription corepressor activity;GO:0019899//enzyme binding,K15617//Transcriptional misregulation in cancer
8862,0,0,0,0,0,11,1,0,0,0,1,0,APLN;apelin,GO:0005576//extracellular region,GO:0006955//immune response;GO:0007595//lactation;GO:0007165//signal transduction,GO:0031704//apelin receptor binding;GO:0005102//receptor binding;GO:0005179//hormone activity,-
8863,0,14,1,1,28,0,9,42,58,0,9,0,PER3;period circadian clock 3,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007165//signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0032922//circadian regulation of gene expression;GO:0045187//regulation of circadian sleep/wake cycle, sleep",GO:0019900//kinase binding;GO:0004871//signal transducer activity;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding,K02633//Circadian rhythm - fly;Herpes simplex infection;Transcriptional misregulation in cancer;Circadian rhythm - mammal
8864,0,0,0,18,1,1,20,65,53,0,0,0,PER2;period circadian clock 2,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,"GO:0007623//circadian rhythm;GO:0031397//negative regulation of protein ubiquitination;GO:0019229//regulation of vasoconstriction;GO:0045892//negative regulation of transcription, DNA-templated;GO:0070345//negative regulation of fat cell proliferation;GO:0042752//regulation of circadian rhythm;GO:0050767//regulation of neurogenesis;GO:0007165//signal transduction;GO:0050872//white fat cell differentiation;GO:0097167//circadian regulation of translation;GO:0051726//regulation of cell cycle;GO:0006631//fatty acid metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050796//regulation of insulin secretion;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0019249//lactate biosynthetic process;GO:0006094//gluconeogenesis;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0002931//response to ischemia;GO:0005978//glycogen biosynthetic process;GO:0070932//histone H3 deacetylation;GO:0042754//negative regulation of circadian rhythm;GO:0051946//regulation of glutamate uptake involved in transmission of nerve impulse",GO:0001222//transcription corepressor binding;GO:0019900//kinase binding;GO:0043130//ubiquitin binding;GO:0070063//RNA polymerase binding;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0005515//protein binding;GO:0000989//transcription factor binding transcription factor activity;GO:0036002//pre-mRNA binding;GO:0003713//transcription coactivator activity;GO:0035257//nuclear hormone receptor binding;GO:1990226//histone methyltransferase binding;GO:0004871//signal transducer activity;GO:0042826//histone deacetylase binding,K02633//Circadian rhythm - mammal;Transcriptional misregulation in cancer;Circadian rhythm - fly;Herpes simplex infection
8867,0,0,0,0,17,46,43,8,134,0,11,0,SYNJ1;synaptojanin 1,GO:0005829//cytosol,GO:0046856//phosphatidylinositol dephosphorylation;GO:0048488//synaptic vesicle endocytosis;GO:0006661//phosphatidylinositol biosynthetic process;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0006796//phosphate-containing compound metabolic process;GO:0008219//cell death;GO:0006644//phospholipid metabolic process,"GO:0003723//RNA binding;GO:0004445//inositol-polyphosphate 5-phosphatase activity;GO:0000166//nucleotide binding;GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity",K01099//Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
8869,0,0,0,0,12,14,0,21,39,0,0,0,"ST3GAL5;ST3 beta-galactoside alpha-2,3-sialyltransferase 5",GO:0005887//integral component of plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0030173//integral component of Golgi membrane,GO:0001574//ganglioside biosynthetic process;GO:0097503//sialylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0006486//protein glycosylation;GO:0005975//carbohydrate metabolic process,"GO:0008373//sialyltransferase activity;GO:0047291//lactosylceramide alpha-2,3-sialyltransferase activity;GO:0004513//neolactotetraosylceramide alpha-2,3-sialyltransferase activity",K03370//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
887,0,0,0,0,0,0,45,0,12,0,0,0,CCKBR;cholecystokinin B receptor,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0008152//metabolic process;GO:0001696//gastric acid secretion;GO:0007166//cell surface receptor signaling pathway;GO:0007631//feeding behavior;GO:0043551//regulation of phosphatidylinositol 3-kinase activity;GO:0008283//cell proliferation;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0048565//digestive tract development;GO:0048732//gland development;GO:0007600//sensory perception;GO:0038188//cholecystokinin signaling pathway;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007586//digestion;GO:0008284//positive regulation of cell proliferation,GO:0031741//type B gastrin/cholecystokinin receptor binding;GO:0004951//cholecystokinin receptor activity;GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005515//protein binding;GO:0015054//gastrin receptor activity;GO:0046935//1-phosphatidylinositol-3-kinase regulator activity,K04195//Gastric acid secretion;Calcium signaling pathway;Neuroactive ligand-receptor interaction
8871,0,59,1,50,125,40,88,0,66,1,6,16,SYNJ2;synaptojanin 2,GO:0005829//cytosol;GO:0016020//membrane,GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0044281//small molecule metabolic process,"GO:0004439//phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding",K01099//Inositol phosphate metabolism;Phosphatidylinositol signaling system;Metabolic pathways
8872,33,1,0,40,74,0,0,0,0,0,45,0,CDC123;cell division cycle 123,GO:0005737//cytoplasm,GO:0007050//cell cycle arrest;GO:0007346//regulation of mitotic cell cycle;GO:0008284//positive regulation of cell proliferation;GO:0051301//cell division,-,-
8874,0,6,2,12,104,24,11,0,110,0,24,0,ARHGEF7;Rho guanine nucleotide exchange factor (GEF) 7,GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0043005//neuron projection;GO:0001726//ruffle;GO:0005938//cell cortex;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0030027//lamellipodium,GO:0032855//positive regulation of Rac GTPase activity;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0002244//hematopoietic progenitor cell differentiation;GO:0043547//positive regulation of GTPase activity;GO:2000394//positive regulation of lamellipodium morphogenesis;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0030032//lamellipodium assembly;GO:0007399//nervous system development;GO:0048041//focal adhesion assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0010763//positive regulation of fibroblast migration,GO:0019901//protein kinase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity,K13710//Regulation of actin cytoskeleton
88745,113,20,0,1,31,0,0,0,11,0,0,0,RRP36;ribosomal RNA processing 36 homolog (S. cerevisiae),GO:0005634//nucleus;GO:0005730//nucleolus,GO:0042274//ribosomal small subunit biogenesis;GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
8875,0,0,0,0,0,0,0,38,38,0,8,0,VNN2;vanin 2,GO:0031225//anchored component of membrane;GO:0005886//plasma membrane,GO:0006928//cellular component movement;GO:0015939//pantothenate metabolic process,GO:0017159//pantetheine hydrolase activity,K08069//Pantothenate and CoA biosynthesis
8876,0,0,0,0,0,0,0,0,7,0,0,0,VNN1;vanin 1,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031225//anchored component of membrane,GO:0006928//cellular component movement;GO:0002544//chronic inflammatory response;GO:0015939//pantothenate metabolic process;GO:0006979//response to oxidative stress;GO:0016337//single organismal cell-cell adhesion;GO:0045087//innate immune response;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0002526//acute inflammatory response;GO:0006954//inflammatory response;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,GO:0017159//pantetheine hydrolase activity;GO:0034235//GPI anchor binding,K08069//Pantothenate and CoA biosynthesis
8877,0,0,0,0,0,1,0,0,30,0,0,0,SPHK1;sphingosine kinase 1,GO:0005829//cytosol;GO:0008021//synaptic vesicle;GO:0005886//plasma membrane;GO:0030424//axon;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030148//sphingolipid biosynthetic process;GO:0001568//blood vessel development;GO:0010803//regulation of tumor necrosis factor-mediated signaling pathway;GO:0045931//positive regulation of mitotic cell cycle;GO:0007565//female pregnancy;GO:0043066//negative regulation of apoptotic process;GO:0007420//brain development;GO:0048146//positive regulation of fibroblast proliferation;GO:0035556//intracellular signal transduction;GO:0046834//lipid phosphorylation;GO:0030307//positive regulation of cell growth;GO:0009267//cellular response to starvation;GO:0031398//positive regulation of protein ubiquitination;GO:0001956//positive regulation of neurotransmitter secretion;GO:0051084//'de novo' posttranslational protein folding;GO:0001934//positive regulation of protein phosphorylation;GO:0032651//regulation of interleukin-1 beta production;GO:0006670//sphingosine metabolic process;GO:0006665//sphingolipid metabolic process;GO:0044281//small molecule metabolic process;GO:0019371//cyclooxygenase pathway;GO:0033198//response to ATP;GO:0046521//sphingoid catabolic process;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0045987//positive regulation of smooth muscle contraction;GO:0045766//positive regulation of angiogenesis;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0014075//response to amine;GO:0030335//positive regulation of cell migration;GO:0042346//positive regulation of NF-kappaB import into nucleus;GO:0006457//protein folding;GO:0070301//cellular response to hydrogen peroxide;GO:0007165//signal transduction;GO:0032570//response to progesterone;GO:0032026//response to magnesium ion;GO:0010976//positive regulation of neuron projection development;GO:0006954//inflammatory response;GO:0070555//response to interleukin-1;GO:0019722//calcium-mediated signaling;GO:0071363//cellular response to growth factor stimulus;GO:0044267//cellular protein metabolic process,GO:0008481//sphinganine kinase activity;GO:0004143//diacylglycerol kinase activity;GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding;GO:0000287//magnesium ion binding;GO:0003951//NAD+ kinase activity;GO:0003677//DNA binding;GO:0017050//D-erythro-sphingosine kinase activity;GO:0005516//calmodulin binding;GO:0005524//ATP binding,K04718//VEGF signaling pathway;Sphingolipid metabolism;Tuberculosis;Fc gamma R-mediated phagocytosis;Calcium signaling pathway;Metabolic pathways
8878,83,130,20,129,282,21,0,318,50,0,293,2,SQSTM1;sequestosome 1,GO:0000407//pre-autophagosomal structure;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0016234//inclusion body;GO:0005770//late endosome;GO:0000932//cytoplasmic mRNA processing body;GO:0016235//aggresome;GO:0005737//cytoplasm;GO:0031410//cytoplasmic vesicle;GO:0005654//nucleoplasm;GO:0016605//PML body;GO:0005829//cytosol;GO:0005776//autophagic vacuole;GO:0005764//lysosome,GO:0043066//negative regulation of apoptotic process;GO:0008104//protein localization;GO:0035556//intracellular signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0046578//regulation of Ras protein signal transduction;GO:0006914//autophagy;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0006468//protein phosphorylation;GO:0016197//endosomal transport;GO:0006950//response to stress;GO:0051291//protein heterooligomerization;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0001934//positive regulation of protein phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030154//cell differentiation;GO:0016239//positive regulation of macroautophagy;GO:0016236//macroautophagy;GO:0002376//immune system process,GO:0004674//protein serine/threonine kinase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0042169//SH2 domain binding;GO:0043130//ubiquitin binding;GO:0005080//protein kinase C binding;GO:0019901//protein kinase binding;GO:0070530//K63-linked polyubiquitin binding;GO:0042802//identical protein binding;GO:0030971//receptor tyrosine kinase binding,K14381//Osteoclast differentiation
8879,0,44,0,0,44,13,3,1,58,0,11,1,SGPL1;sphingosine-1-phosphate lyase 1,GO:0005783//endoplasmic reticulum;GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0040014//regulation of multicellular organism growth;GO:0009791//post-embryonic development;GO:0048705//skeletal system morphogenesis;GO:0008210//estrogen metabolic process;GO:0006665//sphingolipid metabolic process;GO:0030097//hemopoiesis;GO:0007283//spermatogenesis;GO:0097190//apoptotic signaling pathway;GO:0008209//androgen metabolic process;GO:0001553//luteinization;GO:0033327//Leydig cell differentiation;GO:0001822//kidney development;GO:0030148//sphingolipid biosynthetic process;GO:0001570//vasculogenesis;GO:0006672//ceramide metabolic process;GO:0044281//small molecule metabolic process;GO:0010761//fibroblast migration;GO:0030149//sphingolipid catabolic process;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0006631//fatty acid metabolic process;GO:0060325//face morphogenesis;GO:0060021//palate development,GO:0030170//pyridoxal phosphate binding;GO:0016831//carboxy-lyase activity;GO:0005515//protein binding;GO:0008117//sphinganine-1-phosphate aldolase activity,K01634//Metabolic pathways;Sphingolipid metabolism
8880,0,63,2,14,217,0,1,16,43,0,5,0,FUBP1;far upstream element (FUSE) binding protein 1,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010628//positive regulation of gene expression,GO:0003697//single-stranded DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
8881,0,33,0,9,94,0,7,0,4,0,0,0,CDC16;cell division cycle 16,GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005819//spindle;GO:0005876//spindle microtubule;GO:0005654//nucleoplasm,GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0070979//protein K11-linked ubiquitination;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007067//mitotic nuclear division;GO:0007088//regulation of mitosis;GO:0008283//cell proliferation;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,K03353//Cell cycle;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;HTLV-I infection;Oocyte meiosis;Meiosis - yeast
8882,217,48,0,1,36,0,0,52,17,0,0,0,ZPR1;ZPR1 zinc finger,GO:0030424//axon;GO:0005730//nucleolus;GO:0043204//perikaryon;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0015030//Cajal body;GO:0097504//Gemini of coiled bodies;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0032797//SMN complex;GO:0030426//growth cone;GO:0005654//nucleoplasm,GO:1902742//apoptotic process involved in development;GO:2000672//negative regulation of motor neuron apoptotic process;GO:0021510//spinal cord development;GO:1990261//pre-mRNA catabolic process;GO:0071931//positive regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0033120//positive regulation of RNA splicing;GO:0045927//positive regulation of growth;GO:0061564//axon development;GO:0001833//inner cell mass cell proliferation;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0008283//cell proliferation;GO:0001834//trophectodermal cell proliferation;GO:0006397//mRNA processing;GO:0031641//regulation of myelination;GO:0010628//positive regulation of gene expression;GO:0008380//RNA splicing;GO:0042307//positive regulation of protein import into nucleus;GO:0030576//Cajal body organization;GO:0042023//DNA endoreduplication;GO:0007165//signal transduction;GO:0000226//microtubule cytoskeleton organization,GO:0030971//receptor tyrosine kinase binding;GO:0031369//translation initiation factor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,-
8883,0,0,0,15,23,18,24,0,103,0,0,0,NAE1;NEDD8 activating enzyme E1 subunit 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0045116//protein neddylation;GO:0051402//neuron apoptotic process;GO:0043523//regulation of neuron apoptotic process;GO:0042981//regulation of apoptotic process;GO:0033314//mitotic DNA replication checkpoint,GO:0019781//NEDD8 activating enzyme activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0046982//protein heterodimerization activity,K04532//Alzheimer's disease
8884,0,19,0,0,26,23,0,43,27,0,33,0,"SLC5A6;solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6",GO:0031526//brush border membrane;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0012506//vesicle membrane;GO:0005887//integral component of plasma membrane,GO:0006768//biotin metabolic process;GO:0006766//vitamin metabolic process;GO:0006810//transport;GO:0055085//transmembrane transport;GO:0015939//pantothenate metabolic process;GO:0006814//sodium ion transport;GO:0015887//pantothenate transmembrane transport;GO:0044281//small molecule metabolic process;GO:0015878//biotin transport;GO:0006767//water-soluble vitamin metabolic process,GO:0008523//sodium-dependent multivitamin transmembrane transporter activity,K14386//Vitamin digestion and absorption
8886,0,27,3,33,94,0,14,0,22,0,0,0,DDX18;DEAD (Asp-Glu-Ala-Asp) box polypeptide 18,GO:0005730//nucleolus;GO:0016020//membrane,GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
8887,55,33,0,61,205,9,0,0,22,31,0,0,TAX1BP1;Tax1 (human T-cell leukemia virus type I) binding protein 1,GO:0005829//cytosol,GO:0006915//apoptotic process;GO:0045087//innate immune response;GO:0043066//negative regulation of apoptotic process;GO:0032480//negative regulation of type I interferon production;GO:0032088//negative regulation of NF-kappaB transcription factor activity,GO:0019900//kinase binding;GO:0005515//protein binding,-
8888,0,122,103,110,186,24,39,31,60,0,92,0,MCM3AP;minichromosome maintenance complex component 3 associated protein,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005643//nuclear pore;GO:0005634//nucleus,GO:0002376//immune system process;GO:0006260//DNA replication;GO:0051028//mRNA transport;GO:0006606//protein import into nucleus,"GO:0016746//transferase activity, transferring acyl groups;GO:0003677//DNA binding",-
889,1,63,0,16,39,25,0,117,17,0,24,0,"KRIT1;KRIT1, ankyrin repeat containing",GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005886//plasma membrane;GO:0005615//extracellular space,GO:0007264//small GTPase mediated signal transduction;GO:0016525//negative regulation of angiogenesis;GO:0050790//regulation of catalytic activity;GO:0001937//negative regulation of endothelial cell proliferation;GO:0001525//angiogenesis;GO:0032092//positive regulation of protein binding;GO:2000114//regulation of establishment of cell polarity;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0045454//cell redox homeostasis;GO:0010596//negative regulation of endothelial cell migration,"GO:0032403//protein complex binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0005083//small GTPase regulator activity;GO:0005515//protein binding;GO:0008017//microtubule binding",K11447//Transcriptional misregulation in cancer;K06271//Focal adhesion;HTLV-I infection
8890,95,20,3,13,43,0,0,0,21,0,0,0,"EIF2B4;eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa",GO:0005737//cytoplasm;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005829//cytosol,GO:0042552//myelination;GO:0001541//ovarian follicle development;GO:0006413//translational initiation;GO:0043434//response to peptide hormone;GO:0044267//cellular protein metabolic process;GO:0045947//negative regulation of translational initiation;GO:0014003//oligodendrocyte development;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0051716//cellular response to stimulus;GO:0006412//translation;GO:0009408//response to heat;GO:0032057//negative regulation of translational initiation in response to stress;GO:0006417//regulation of translation;GO:0010467//gene expression;GO:0006446//regulation of translational initiation;GO:0009749//response to glucose;GO:0043547//positive regulation of GTPase activity,GO:0046523//S-methyl-5-thioribose-1-phosphate isomerase activity;GO:0005515//protein binding;GO:0031369//translation initiation factor binding;GO:0003743//translation initiation factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K03680//Metabolic pathways;Cysteine and methionine metabolism;RNA transport
8891,0,19,0,12,32,0,0,0,17,0,6,0,"EIF2B3;eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa",GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005737//cytoplasm,GO:0043547//positive regulation of GTPase activity;GO:0014003//oligodendrocyte development;GO:0051716//cellular response to stimulus;GO:0009749//response to glucose;GO:0044267//cellular protein metabolic process;GO:0043434//response to peptide hormone;GO:0032057//negative regulation of translational initiation in response to stress;GO:0010467//gene expression;GO:0006412//translation;GO:0009408//response to heat;GO:0006413//translational initiation,"GO:0005085//guanyl-nucleotide exchange factor activity;GO:0003743//translation initiation factor activity;GO:0008135//translation factor activity, nucleic acid binding;GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity",K03241//RNA transport
8892,0,0,0,1,17,8,1,0,0,67,4,0,"EIF2B2;eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa",GO:0005737//cytoplasm;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005829//cytosol,GO:0044267//cellular protein metabolic process;GO:0043434//response to peptide hormone;GO:0010467//gene expression;GO:0007417//central nervous system development;GO:0006412//translation;GO:0001541//ovarian follicle development;GO:0042552//myelination;GO:0006413//translational initiation;GO:0009408//response to heat;GO:0043547//positive regulation of GTPase activity;GO:0014003//oligodendrocyte development;GO:0019509//L-methionine biosynthetic process from methylthioadenosine;GO:0006446//regulation of translational initiation;GO:0051716//cellular response to stimulus;GO:0009749//response to glucose,GO:0005515//protein binding;GO:0046523//S-methyl-5-thioribose-1-phosphate isomerase activity;GO:0003743//translation initiation factor activity;GO:0005525//GTP binding;GO:0005524//ATP binding;GO:0005085//guanyl-nucleotide exchange factor activity,K03754//RNA transport
8893,0,0,87,28,112,1,0,98,15,0,34,64,"EIF2B5;eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa",GO:0005829//cytosol;GO:0005851//eukaryotic translation initiation factor 2B complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0032057//negative regulation of translational initiation in response to stress;GO:0010467//gene expression;GO:0048708//astrocyte differentiation;GO:0035690//cellular response to drug;GO:0006412//translation;GO:0009408//response to heat;GO:0043547//positive regulation of GTPase activity;GO:0009749//response to glucose;GO:0044267//cellular protein metabolic process;GO:0043434//response to peptide hormone;GO:0001541//ovarian follicle development;GO:0042552//myelination;GO:0006413//translational initiation;GO:0014002//astrocyte development;GO:0014003//oligodendrocyte development;GO:0034976//response to endoplasmic reticulum stress;GO:0045948//positive regulation of translational initiation,GO:0031369//translation initiation factor binding;GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0003743//translation initiation factor activity,K03240//RNA transport
8894,0,26,0,12,53,10,0,0,31,0,0,0,"EIF2S2;eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa",GO:0005850//eukaryotic translation initiation factor 2 complex;GO:0005829//cytosol,GO:0006413//translational initiation;GO:0006412//translation;GO:0002176//male germ cell proliferation;GO:0001701//in utero embryonic development;GO:0010467//gene expression;GO:0008584//male gonad development;GO:0044267//cellular protein metabolic process,"GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0003723//RNA binding;GO:0003743//translation initiation factor activity",K03238//RNA transport
8895,0,3,0,74,257,8,0,0,43,0,0,0,CPNE3;copine III,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0016192//vesicle-mediated transport;GO:0006629//lipid metabolic process,GO:0004674//protein serine/threonine kinase activity;GO:0044822//poly(A) RNA binding;GO:0005215//transporter activity;GO:0005544//calcium-dependent phospholipid binding,K15290//Synaptic vesicle cycle;K06491//Prion diseases;Cell adhesion molecules (CAMs)
8896,0,31,0,28,71,0,0,0,0,0,51,0,BUD31;BUD31 homolog (S. cerevisiae),GO:0005634//nucleus,GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003700//sequence-specific DNA binding transcription factor activity,K12873//Spliceosome
8897,10,42,2,43,50,0,19,64,5,0,13,19,MTMR3;myotubularin related protein 3,GO:0005730//nucleolus;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0005634//nucleus,GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0044281//small molecule metabolic process,"GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity;GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0004438//phosphatidylinositol-3-phosphatase activity",-
8898,0,76,128,91,363,0,0,0,31,44,8,0,MTMR2;myotubularin related protein 2,GO:0030425//dendrite;GO:0097481//neuronal postsynaptic density;GO:0008021//synaptic vesicle;GO:0005774//vacuolar membrane;GO:0043197//dendritic spine;GO:0097060//synaptic membrane;GO:0005737//cytoplasm;GO:0030424//axon;GO:0005829//cytosol;GO:0031901//early endosome membrane;GO:0005634//nucleus,GO:0097062//dendritic spine maintenance;GO:0006644//phospholipid metabolic process;GO:0002091//negative regulation of receptor internalization;GO:0045806//negative regulation of endocytosis;GO:2000643//positive regulation of early endosome to late endosome transport;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0090394//negative regulation of excitatory postsynaptic membrane potential;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046856//phosphatidylinositol dephosphorylation;GO:0008219//cell death;GO:2000645//negative regulation of receptor catabolic process;GO:0048666//neuron development;GO:0044281//small molecule metabolic process;GO:0031642//negative regulation of myelination;GO:0032288//myelin assembly;GO:0051262//protein tetramerization;GO:0046855//inositol phosphate dephosphorylation,"GO:0052629//phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0042803//protein homodimerization activity;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity",K01112//Fructose and mannose metabolism
8899,0,3,0,8,58,36,0,0,29,0,12,0,PRPF4B;pre-mRNA processing factor 4B,GO:0005634//nucleus;GO:0005694//chromosome;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome;GO:0008380//RNA splicing;GO:0006468//protein phosphorylation",GO:0005524//ATP binding;GO:0004672//protein kinase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
89,0,0,0,0,0,19,0,12,10,0,36,88,"ACTN3;actinin, alpha 3",GO:0005829//cytosol;GO:0031143//pseudopodium;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005884//actin filament,GO:0048041//focal adhesion assembly;GO:0042981//regulation of apoptotic process;GO:0030049//muscle filament sliding,GO:0003779//actin binding;GO:0008307//structural constituent of muscle;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005178//integrin binding;GO:0005509//calcium ion binding,K05699//Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Amoebiasis;Focal adhesion;Adherens junction
890,0,0,0,10,13,0,12,0,17,0,0,0,CCNA2;cyclin A2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0001939//female pronucleus;GO:0001940//male pronucleus,"GO:0032355//response to estradiol;GO:0007067//mitotic nuclear division;GO:0007265//Ras protein signal transduction;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0031100//organ regeneration;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:0048146//positive regulation of fibroblast proliferation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0033762//response to glucagon",GO:0019901//protein kinase binding;GO:0005515//protein binding,K06627//Pathways in cancer;Acute myeloid leukemia;Transcriptional misregulation in cancer;Epstein-Barr virus infection;Progesterone-mediated oocyte maturation;Cell cycle
8900,0,0,0,0,0,0,0,0,48,0,0,0,CCNA1;cyclin A1,GO:0005654//nucleoplasm;GO:0015630//microtubule cytoskeleton;GO:0005829//cytosol,GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0007283//spermatogenesis;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007141//male meiosis I;GO:0007067//mitotic nuclear division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0010389//regulation of G2/M transition of mitotic cell cycle,GO:0005515//protein binding;GO:0019901//protein kinase binding,K06627//Acute myeloid leukemia;Pathways in cancer;Cell cycle;Progesterone-mediated oocyte maturation;Epstein-Barr virus infection;Transcriptional misregulation in cancer
8904,0,0,0,5,33,0,26,19,6,0,0,0,CPNE1;copine I,GO:0070062//extracellular vesicular exosome,GO:0016192//vesicle-mediated transport;GO:0006629//lipid metabolic process,GO:0005544//calcium-dependent phospholipid binding;GO:0005215//transporter activity;GO:0001786//phosphatidylserine binding,K06491//Cell adhesion molecules (CAMs);Prion diseases
8905,0,0,1,0,11,0,0,0,47,0,0,0,"AP1S2;adaptor-related protein complex 1, sigma 2 subunit",GO:0032588//trans-Golgi network membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0005765//lysosomal membrane;GO:0030119//AP-type membrane coat adaptor complex;GO:0005905//coated pit,GO:0050690//regulation of defense response to virus by virus;GO:0061024//membrane organization;GO:0006886//intracellular protein transport;GO:0016032//viral process;GO:0006892//post-Golgi vesicle-mediated transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0008565//protein transporter activity,K12394//Lysosome
8906,78,35,7,20,36,0,61,41,21,120,7,0,"AP1G2;adaptor-related protein complex 1, gamma 2 subunit",GO:0030133//transport vesicle;GO:0005798//Golgi-associated vesicle;GO:0030121//AP-1 adaptor complex;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0010008//endosome membrane,GO:0006886//intracellular protein transport;GO:0016032//viral process;GO:0016192//vesicle-mediated transport,GO:0008565//protein transporter activity;GO:0005515//protein binding,K12391//Lysosome
8907,0,0,0,1,4,0,52,0,14,0,2,0,"AP1M1;adaptor-related protein complex 1, mu 1 subunit",GO:0032588//trans-Golgi network membrane;GO:0005829//cytosol;GO:0005765//lysosomal membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0030131//clathrin adaptor complex;GO:0070062//extracellular vesicular exosome;GO:0030659//cytoplasmic vesicle membrane;GO:0016020//membrane;GO:0000139//Golgi membrane,GO:0016032//viral process;GO:0006886//intracellular protein transport;GO:0006892//post-Golgi vesicle-mediated transport;GO:0035646//endosome to melanosome transport;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0050690//regulation of defense response to virus by virus;GO:0061024//membrane organization;GO:0032438//melanosome organization,GO:0005515//protein binding,K12393//Lysosome
8908,0,0,0,10,2,0,0,0,33,0,3,0,GYG2;glycogenin 2,GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0005978//glycogen biosynthetic process;GO:0005980//glycogen catabolic process;GO:0006006//glucose metabolic process;GO:0005975//carbohydrate metabolic process,GO:0008466//glycogenin glucosyltransferase activity,-
8909,0,0,0,5,0,0,19,18,13,0,0,0,"ENDOU;endonuclease, polyU-specific",GO:0005737//cytoplasm;GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005886//plasma membrane,"GO:0007565//female pregnancy;GO:0006955//immune response;GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006898//receptor-mediated endocytosis;GO:0006508//proteolysis",GO:0030145//manganese ion binding;GO:0008083//growth factor activity;GO:0030247//polysaccharide binding;GO:0008236//serine-type peptidase activity;GO:0005044//scavenger receptor activity;GO:0003723//RNA binding;GO:0004521//endoribonuclease activity,-
891,0,0,0,0,0,8,20,0,0,192,0,0,CCNB1;cyclin B1,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005654//nucleoplasm;GO:0000942//condensed nuclear chromosome outer kinetochore;GO:0005829//cytosol;GO:0005634//nucleus;GO:0000922//spindle pole,GO:0071283//cellular response to iron(III) ion;GO:0042493//response to drug;GO:0001701//in utero embryonic development;GO:0071456//cellular response to hypoxia;GO:0007080//mitotic metaphase plate congression;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0033129//positive regulation of histone phosphorylation;GO:0009612//response to mechanical stimulus;GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0043148//mitotic spindle stabilization;GO:0006468//protein phosphorylation;GO:0060623//regulation of chromosome condensation;GO:0007077//mitotic nuclear envelope disassembly;GO:0042246//tissue regeneration;GO:0055015//ventricular cardiac muscle cell development;GO:0001556//oocyte maturation;GO:0071174//mitotic spindle checkpoint;GO:0001933//negative regulation of protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0071407//cellular response to organic cyclic compound;GO:0006461//protein complex assembly;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0010629//negative regulation of gene expression;GO:0048565//digestive tract development;GO:0007283//spermatogenesis;GO:0071398//cellular response to fatty acid;GO:0000082//G1/S transition of mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0046680//response to DDT;GO:0031442//positive regulation of mRNA 3'-end processing;GO:0051987//positive regulation of attachment of spindle microtubules to kinetochore,GO:0005515//protein binding;GO:0005113//patched binding;GO:0019901//protein kinase binding;GO:0016301//kinase activity,K05868//Progesterone-mediated oocyte maturation;Cell cycle;p53 signaling pathway;Oocyte meiosis;HTLV-I infection
8910,0,0,0,0,0,0,0,0,10,0,0,0,"SGCE;sarcoglycan, epsilon",GO:0042383//sarcolemma;GO:0032590//dendrite membrane;GO:0005887//integral component of plasma membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0016012//sarcoglycan complex;GO:0016010//dystrophin-associated glycoprotein complex;GO:0005794//Golgi apparatus;GO:0005856//cytoskeleton,GO:0007517//muscle organ development;GO:0007160//cell-matrix adhesion,GO:0005509//calcium ion binding,K12565//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Dilated cardiomyopathy
8911,119,0,0,0,6,30,48,155,86,0,4,1,"CACNA1I;calcium channel, voltage-dependent, T type, alpha 1I subunit",GO:0005891//voltage-gated calcium channel complex;GO:0005886//plasma membrane,GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0030431//sleep;GO:0007165//signal transduction;GO:0006810//transport;GO:0019228//neuronal action potential;GO:0070588//calcium ion transmembrane transport;GO:0030317//sperm motility;GO:0007411//axon guidance;GO:0034765//regulation of ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity;GO:0005515//protein binding,K04856//MAPK signaling pathway;Calcium signaling pathway
8912,1,0,0,0,0,9,34,0,65,0,13,126,"CACNA1H;calcium channel, voltage-dependent, T type, alpha 1H subunit",GO:0005891//voltage-gated calcium channel complex;GO:0005901//caveola;GO:0016021//integral component of membrane;GO:0042383//sarcolemma;GO:0005886//plasma membrane,GO:0032870//cellular response to hormone stimulus;GO:0006810//transport;GO:0007520//myoblast fusion;GO:0032342//aldosterone biosynthetic process;GO:0034765//regulation of ion transmembrane transport;GO:0006936//muscle contraction;GO:0007517//muscle organ development;GO:0070588//calcium ion transmembrane transport;GO:0070509//calcium ion import;GO:0086010//membrane depolarization during action potential;GO:2000344//positive regulation of acrosome reaction;GO:0035865//cellular response to potassium ion;GO:0008016//regulation of heart contraction;GO:0034651//cortisol biosynthetic process;GO:0007411//axon guidance;GO:0042391//regulation of membrane potential,GO:0008332//low voltage-gated calcium channel activity;GO:0097110//scaffold protein binding;GO:0046872//metal ion binding,K04855//Calcium signaling pathway;MAPK signaling pathway
89122,0,28,1,24,58,14,0,65,44,0,0,0,TRIM4;tripartite motif containing 4,GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0070206//protein trimerization,GO:0008270//zinc ion binding,-
8913,2,0,0,0,0,13,40,0,50,3,10,0,"CACNA1G;calcium channel, voltage-dependent, T type, alpha 1G subunit",GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex,GO:0010045//response to nickel cation;GO:0060371//regulation of atrial cardiac muscle cell membrane depolarization;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0086010//membrane depolarization during action potential;GO:0070509//calcium ion import;GO:0070588//calcium ion transmembrane transport;GO:0042391//regulation of membrane potential;GO:0034765//regulation of ion transmembrane transport;GO:0002027//regulation of heart rate;GO:0007268//synaptic transmission;GO:0007411//axon guidance;GO:0006810//transport,GO:0008332//low voltage-gated calcium channel activity;GO:0097110//scaffold protein binding,K04854//Type II diabetes mellitus;Calcium signaling pathway;MAPK signaling pathway
8914,0,0,0,0,0,49,0,0,37,0,0,0,TIMELESS;timeless circadian clock,GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0009628//response to abiotic stimulus;GO:0002009//morphogenesis of an epithelium;GO:0042752//regulation of circadian rhythm;GO:0009582//detection of abiotic stimulus;GO:0006351//transcription, DNA-templated;GO:0048754//branching morphogenesis of an epithelial tube;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0042127//regulation of cell proliferation;GO:0044770//cell cycle phase transition;GO:0006974//cellular response to DNA damage stimulus;GO:0007067//mitotic nuclear division",GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
8915,0,1,43,2,62,0,0,54,43,0,0,0,BCL10;B-cell CLL/lymphoma 10,GO:0042101//T cell receptor complex;GO:0005829//cytosol;GO:0032449//CBM complex;GO:0048471//perinuclear region of cytoplasm;GO:0001772//immunological synapse;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005881//cytoplasmic microtubule;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0005737//cytoplasm;GO:0043234//protein complex;GO:0046696//lipopolysaccharide receptor complex,"GO:0042226//interleukin-6 biosynthetic process;GO:0070231//T cell apoptotic process;GO:0002250//adaptive immune response;GO:0002224//toll-like receptor signaling pathway;GO:0032094//response to food;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0042327//positive regulation of phosphorylation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0016064//immunoglobulin mediated immune response;GO:2001238//positive regulation of extrinsic apoptotic signaling pathway;GO:0008219//cell death;GO:0050870//positive regulation of T cell activation;GO:0051259//protein oligomerization;GO:0045087//innate immune response;GO:0045416//positive regulation of interleukin-8 biosynthetic process;GO:0042109//lymphotoxin A biosynthetic process;GO:0051260//protein homooligomerization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0050856//regulation of T cell receptor signaling pathway;GO:0002237//response to molecule of bacterial origin;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0001783//B cell apoptotic process;GO:0050852//T cell receptor signaling pathway;GO:0071260//cellular response to mechanical stimulus;GO:0006968//cellular defense response;GO:0031398//positive regulation of protein ubiquitination;GO:0001843//neural tube closure;GO:0032765//positive regulation of mast cell cytokine production;GO:0009620//response to fungus",GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0019899//enzyme binding;GO:0051059//NF-kappaB binding;GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0008134//transcription factor binding;GO:0043422//protein kinase B binding;GO:0019900//kinase binding;GO:0043130//ubiquitin binding;GO:0008022//protein C-terminus binding;GO:0019209//kinase activator activity;GO:0002020//protease binding,K07368//T cell receptor signaling pathway;NF-kappa B signaling pathway;Tuberculosis;B cell receptor signaling pathway
8916,0,78,2,94,98,0,11,0,23,0,3,0,HERC3;HECT and RLD domain containing E3 ubiquitin protein ligase 3,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005634//nucleus,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K10614//Ubiquitin mediated proteolysis
892,0,17,0,41,142,8,4,0,6,0,1,0,CCNC;cyclin C,"GO:0005654//nucleoplasm;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0016592//mediator complex","GO:0007219//Notch signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0010467//gene expression;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity",GO:0005515//protein binding;GO:0019901//protein kinase binding,-
8924,28,113,0,24,64,29,81,172,213,0,72,287,HERC2;HECT and RLD domain containing E3 ubiquitin protein ligase 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005814//centriole;GO:0016020//membrane;GO:0005743//mitochondrial inner membrane,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0007283//spermatogenesis;GO:0006281//DNA repair;GO:0006886//intracellular protein transport;GO:0043547//positive regulation of GTPase activity;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0020037//heme binding;GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0032183//SUMO binding,K10595//Ubiquitin mediated proteolysis
8925,143,90,1,66,130,65,114,68,182,68,2,0,HERC1;HECT and RLD domain containing E3 ubiquitin protein ligase family member 1,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005829//cytosol;GO:0005794//Golgi apparatus,GO:0031175//neuron projection development;GO:0050885//neuromuscular process controlling balance;GO:0010507//negative regulation of autophagy;GO:0043547//positive regulation of GTPase activity;GO:0016567//protein ubiquitination;GO:0021702//cerebellar Purkinje cell differentiation;GO:0006810//transport,GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity;GO:0005086//ARF guanyl-nucleotide exchange factor activity,K10594//Ubiquitin mediated proteolysis
8926,0,0,0,0,0,19,0,0,0,0,0,0,SNURF;SNRPN upstream reading frame,GO:0005634//nucleus,-,-,-
8927,79,0,0,0,1,8,0,3,48,0,18,0,BSN;bassoon presynaptic cytomatrix protein,GO:0030054//cell junction;GO:0030424//axon;GO:0030425//dendrite;GO:0044306//neuron projection terminus;GO:0005634//nucleus,GO:0007268//synaptic transmission,GO:0046872//metal ion binding,-
8928,0,0,0,58,95,0,0,0,10,9,96,1,FOXH1;forkhead box H1,GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0005654//nucleoplasm;GO:0032444//activin responsive factor complex;GO:0005667//transcription factor complex,"GO:0003151//outflow tract morphogenesis;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035909//aorta morphogenesis;GO:0003139//secondary heart field specification;GO:0003222//ventricular trabecula myocardium morphogenesis;GO:0006366//transcription from RNA polymerase II promoter;GO:1900164//nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048318//axial mesoderm development;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0035054//embryonic heart tube anterior/posterior pattern specification;GO:0001947//heart looping;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:2000824//negative regulation of androgen receptor activity;GO:0003215//cardiac right ventricle morphogenesis;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0070410//co-SMAD binding;GO:0044212//transcription regulatory region DNA binding;GO:0001205//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0050681//androgen receptor binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding;GO:0070412//R-SMAD binding;GO:0043425//bHLH transcription factor binding;GO:0046332//SMAD binding;GO:0019904//protein domain specific binding;GO:0035326//enhancer binding,-
8929,84,0,0,0,0,14,32,0,40,0,0,0,PHOX2B;paired-like homeobox 2b,GO:0000790//nuclear chromatin,"GO:0071157//negative regulation of cell cycle arrest;GO:0008285//negative regulation of cell proliferation;GO:0003358//noradrenergic neuron development;GO:0045665//negative regulation of neuron differentiation;GO:0021533//cell differentiation in hindbrain;GO:0002087//regulation of respiratory gaseous exchange by neurological system process;GO:0006351//transcription, DNA-templated;GO:0048484//enteric nervous system development;GO:0048483//autonomic nervous system development;GO:1901166//neural crest cell migration involved in autonomic nervous system development;GO:0071542//dopaminergic neuron differentiation;GO:0071773//cellular response to BMP stimulus;GO:0061549//sympathetic ganglion development;GO:0060541//respiratory system development;GO:0035914//skeletal muscle cell differentiation;GO:0048485//sympathetic nervous system development;GO:0001764//neuron migration;GO:0010468//regulation of gene expression;GO:0003360//brainstem development;GO:0010001//glial cell differentiation;GO:0048839//inner ear development;GO:0045666//positive regulation of neuron differentiation;GO:0003357//noradrenergic neuron differentiation;GO:0010971//positive regulation of G2/M transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding,-
8930,0,53,0,29,41,10,0,0,30,0,0,0,MBD4;methyl-CpG binding domain protein 4,GO:0005654//nucleoplasm;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,"GO:0006284//base-excision repair;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0000737//DNA catabolic process, endonucleolytic;GO:0009314//response to radiation;GO:0006281//DNA repair;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0045008//depyrimidination",GO:0008263//pyrimidine-specific mismatch base pair DNA N-glycosylase activity;GO:0005515//protein binding;GO:0004520//endodeoxyribonuclease activity;GO:0003696//satellite DNA binding,K10801//Base excision repair
8932,0,21,1,75,179,45,2,0,9,0,17,0,MBD2;methyl-CpG binding domain protein 2,GO:0000118//histone deacetylase complex;GO:0043234//protein complex;GO:0005737//cytoplasm;GO:0000792//heterochromatin;GO:0005634//nucleus;GO:0000790//nuclear chromatin,"GO:0042711//maternal behavior;GO:0043623//cellular protein complex assembly;GO:0042127//regulation of cell proliferation;GO:0043044//ATP-dependent chromatin remodeling;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0030177//positive regulation of Wnt signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0035197//siRNA binding;GO:0008327//methyl-CpG binding;GO:0003696//satellite DNA binding;GO:0003729//mRNA binding;GO:0019904//protein domain specific binding;GO:0031492//nucleosomal DNA binding;GO:0070742//C2H2 zinc finger domain binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,-
8933,0,1,1,0,0,0,0,0,14,0,15,0,"FAM127A;family with sequence similarity 127, member A",-,-,-,-
8934,0,31,1,42,57,9,22,0,89,0,12,0,"RAB29;RAB29, member RAS oncogene family",GO:0005802//trans-Golgi network;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm;GO:0005856//cytoskeleton;GO:0005773//vacuole;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0090316//positive regulation of intracellular protein transport;GO:0006184//GTP catabolic process;GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0030154//cell differentiation;GO:0007264//small GTPase mediated signal transduction;GO:0035526//retrograde transport, plasma membrane to Golgi;GO:0006888//ER to Golgi vesicle-mediated transport",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0005515//protein binding,-
8935,0,1,0,1,78,0,0,0,33,0,0,0,SKAP2;src kinase associated phosphoprotein 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0006461//protein complex assembly;GO:0007165//signal transduction;GO:0008285//negative regulation of cell proliferation;GO:0042113//B cell activation;GO:0009967//positive regulation of signal transduction,GO:0005070//SH3/SH2 adaptor activity,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K12490//Endocytosis;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways
8936,0,0,46,0,1,0,22,0,30,12,0,0,"WASF1;WAS protein family, member 1",GO:0030027//lamellipodium;GO:0031209//SCAR complex;GO:0005856//cytoskeleton;GO:0015629//actin cytoskeleton;GO:0045202//synapse;GO:0030054//cell junction;GO:0005741//mitochondrial outer membrane,GO:0016601//Rac protein signal transduction;GO:0006928//cellular component movement;GO:2000601//positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0006461//protein complex assembly;GO:0030041//actin filament polymerization;GO:0072673//lamellipodium morphogenesis,GO:0005515//protein binding;GO:0048365//Rac GTPase binding;GO:0003779//actin binding;GO:0032403//protein complex binding,K05753//Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Salmonella infection;Adherens junction;Fc gamma R-mediated phagocytosis;Shigellosis
8938,0,180,57,37,165,2,0,115,55,0,127,0,BAIAP3;BAI1-associated protein 3,-,GO:0007269//neurotransmitter secretion;GO:0007186//G-protein coupled receptor signaling pathway,GO:0008022//protein C-terminus binding,K15621//Transcriptional misregulation in cancer
8939,128,1,1,5,30,7,0,0,28,0,3,0,FUBP3;far upstream element (FUSE) binding protein 3,GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0010628//positive regulation of gene expression;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
894,0,0,0,0,13,0,13,27,26,1,0,0,CCND2;cyclin D2,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0031965//nuclear membrane;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex,GO:0001934//positive regulation of protein phosphorylation;GO:0007049//cell cycle;GO:0051301//cell division;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0005515//protein binding;GO:0019901//protein kinase binding,K10151//Jak-STAT signaling pathway;HTLV-I infection;Transcriptional misregulation in cancer;Wnt signaling pathway;Cell cycle;Focal adhesion;Measles;p53 signaling pathway
8940,0,0,0,3,0,0,21,63,51,4,22,1,TOP3B;topoisomerase (DNA) III beta,GO:0000793//condensed chromosome;GO:0005634//nucleus,GO:0006265//DNA topological change;GO:0007059//chromosome segregation,GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0003917//DNA topoisomerase type I activity,K03165//Homologous recombination;Fanconi anemia pathway
8941,48,0,0,0,0,23,0,0,7,0,0,0,"CDK5R2;cyclin-dependent kinase 5, regulatory subunit 2 (p39)",GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016533//cyclin-dependent protein kinase 5 holoenzyme complex,GO:0021722//superior olivary nucleus maturation;GO:0001764//neuron migration;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0021819//layer formation in cerebral cortex;GO:0021766//hippocampus development;GO:0071902//positive regulation of protein serine/threonine kinase activity;GO:0045956//positive regulation of calcium ion-dependent exocytosis;GO:0021549//cerebellum development,GO:0016534//cyclin-dependent protein kinase 5 activator activity;GO:0008289//lipid binding,K11716//Cocaine addiction;Alzheimer's disease
8942,0,0,0,0,0,23,27,0,31,0,0,0,KYNU;kynureninase,GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0097053//L-kynurenine catabolic process;GO:0006569//tryptophan catabolic process;GO:0019805//quinolinate biosynthetic process;GO:0034516//response to vitamin B6;GO:0019441//tryptophan catabolic process to kynurenine;GO:0034341//response to interferon-gamma;GO:0034641//cellular nitrogen compound metabolic process;GO:0043420//anthranilate metabolic process;GO:0019442//tryptophan catabolic process to acetyl-CoA;GO:0034354//'de novo' NAD biosynthetic process from tryptophan,GO:0042803//protein homodimerization activity;GO:0030429//kynureninase activity;GO:0030170//pyridoxal phosphate binding,K01556//Tryptophan metabolism;Metabolic pathways
8943,0,30,1,0,39,54,22,10,75,0,1,0,"AP3D1;adaptor-related protein complex 3, delta 1 subunit",GO:0005765//lysosomal membrane;GO:0043195//terminal bouton;GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0030117//membrane coat;GO:0000139//Golgi membrane;GO:0010008//endosome membrane,"GO:0048490//anterograde synaptic vesicle transport;GO:0032438//melanosome organization;GO:0033365//protein localization to organelle;GO:0072657//protein localization to membrane;GO:0035646//endosome to melanosome transport;GO:0008089//anterograde axon cargo transport;GO:0048007//antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0051138//positive regulation of NK T cell differentiation;GO:0061088//regulation of sequestering of zinc ion;GO:0006886//intracellular protein transport;GO:0048499//synaptic vesicle membrane organization;GO:0006726//eye pigment biosynthetic process",GO:0005215//transporter activity;GO:0008565//protein transporter activity,K12396//Lysosome
8945,0,0,1,14,80,9,1,11,68,0,5,0,BTRC;beta-transducin repeat containing E3 ubiquitin protein ligase,GO:0005829//cytosol;GO:0019005//SCF ubiquitin ligase complex;GO:0005634//nucleus,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0031648//protein destabilization;GO:0042752//regulation of circadian rhythm;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0045862//positive regulation of proteolysis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006470//protein dephosphorylation;GO:0016055//Wnt signaling pathway;GO:0007165//signal transduction;GO:0042753//positive regulation of circadian rhythm;GO:0016032//viral process;GO:0048511//rhythmic process;GO:0061136//regulation of proteasomal protein catabolic process;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0045879//negative regulation of smoothened signaling pathway;GO:0051726//regulation of cell cycle;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0071407//cellular response to organic cyclic compound;GO:0016567//protein ubiquitination;GO:0033598//mammary gland epithelial cell proliferation;GO:0000209//protein polyubiquitination;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0060444//branching involved in mammary gland duct morphogenesis;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008013//beta-catenin binding;GO:0046983//protein dimerization activity;GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0045309//protein phosphorylated amino acid binding,K03362//Hedgehog signaling pathway;Wnt signaling pathway;Oocyte meiosis;Circadian rhythm - mammal;Ubiquitin mediated proteolysis;Shigellosis
896,0,1,0,0,1,0,80,23,7,0,0,0,CCND3;cyclin D3,GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005737//cytoplasm;GO:0016020//membrane,GO:0051301//cell division;GO:0045737//positive regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0042098//T cell proliferation;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007049//cell cycle;GO:0007165//signal transduction,GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0019901//protein kinase binding;GO:0005515//protein binding,K10152//Cell cycle;Focal adhesion;Measles;p53 signaling pathway;HTLV-I infection;Wnt signaling pathway;Jak-STAT signaling pathway
8968,0,0,43,0,0,0,0,0,20,0,20,0,"HIST1H3F;histone cluster 1, H3f",GO:0005634//nucleus;GO:0000228//nuclear chromosome;GO:0005654//nucleoplasm;GO:0043234//protein complex;GO:0016020//membrane;GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0060968//regulation of gene silencing;GO:0006325//chromatin organization;GO:0007596//blood coagulation;GO:0006335//DNA replication-dependent nucleosome assembly,GO:0003677//DNA binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K11253//Alcoholism;Transcriptional misregulation in cancer;Systemic lupus erythematosus
8969,0,0,0,0,13,0,0,55,16,0,0,1,"HIST1H2AG;histone cluster 1, H2ag",GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0000786//nucleosome,-,GO:0019899//enzyme binding;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Alcoholism;Systemic lupus erythematosus
8970,0,0,0,0,0,0,71,0,0,0,0,0,"HIST1H2BJ;histone cluster 1, H2bj",GO:0000786//nucleosome;GO:0005615//extracellular space;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006325//chromatin organization;GO:0002227//innate immune response in mucosa;GO:0006334//nucleosome assembly;GO:0019731//antibacterial humoral response;GO:0050830//defense response to Gram-positive bacterium,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11252//Systemic lupus erythematosus;Alcoholism
8971,0,102,18,12,35,0,0,1,13,46,103,0,"H1FX;H1 histone family, member X",GO:0005634//nucleus;GO:0005730//nucleolus;GO:0000786//nucleosome,GO:0006334//nucleosome assembly,GO:0044822//poly(A) RNA binding;GO:0003677//DNA binding,-
8972,0,0,0,0,0,0,44,34,81,0,18,0,MGAM;maltase-glucoamylase (alpha-glucosidase),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane,GO:0044281//small molecule metabolic process;GO:0005983//starch catabolic process;GO:0005975//carbohydrate metabolic process;GO:0044245//polysaccharide digestion,"GO:0032450//maltose alpha-glucosidase activity;GO:0016160//amylase activity;GO:0004339//glucan 1,4-alpha-glucosidase activity;GO:0030246//carbohydrate binding;GO:0003824//catalytic activity",K12047//Starch and sucrose metabolism;Carbohydrate digestion and absorption;Metabolic pathways;Galactose metabolism
8973,0,0,0,0,0,7,55,0,50,0,13,1,"CHRNA6;cholinergic receptor, nicotinic, alpha 6 (neuronal)",GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005892//acetylcholine-gated channel complex;GO:0045211//postsynaptic membrane,GO:0014059//regulation of dopamine secretion;GO:0007268//synaptic transmission;GO:0007165//signal transduction;GO:0006810//transport;GO:0051899//membrane depolarization;GO:0006812//cation transport,GO:0004889//acetylcholine-activated cation-selective channel activity;GO:0015464//acetylcholine receptor activity,K04808//Nicotine addiction;Cholinergic synapse;Neuroactive ligand-receptor interaction
8974,13,0,0,0,0,23,0,0,8,0,7,0,"P4HA2;prolyl 4-hydroxylase, alpha polypeptide II",GO:0016222//procollagen-proline 4-dioxygenase complex;GO:0005783//endoplasmic reticulum;GO:0043231//intracellular membrane-bounded organelle;GO:0005737//cytoplasm;GO:0005788//endoplasmic reticulum lumen;GO:0005634//nucleus,GO:0055114//oxidation-reduction process;GO:0018401//peptidyl-proline hydroxylation to 4-hydroxy-L-proline,"GO:0005506//iron ion binding;GO:0016702//oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen;GO:0009055//electron carrier activity;GO:0004656//procollagen-proline 4-dioxygenase activity;GO:0031418//L-ascorbic acid binding",K00472//Arginine and proline metabolism;Metabolic pathways
8975,48,3,1,0,42,16,0,26,49,0,22,1,USP13;ubiquitin specific peptidase 13 (isopeptidase T-3),-,"GO:0006511//ubiquitin-dependent protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0010506//regulation of autophagy;GO:0030318//melanocyte differentiation;GO:0008283//cell proliferation;GO:0070536//protein K63-linked deubiquitination;GO:0006914//autophagy;GO:0050821//protein stabilization",GO:0043130//ubiquitin binding;GO:0004221//ubiquitin thiolesterase activity;GO:0008242//omega peptidase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0031625//ubiquitin protein ligase binding;GO:0004197//cysteine-type endopeptidase activity,-
89758,0,0,0,0,0,0,24,0,0,0,0,0,C6orf7;chromosome 6 open reading frame 7,-,-,-,-
8976,0,47,0,13,79,0,0,54,0,0,14,0,WASL;Wiskott-Aldrich syndrome-like,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030478//actin cap;GO:0030027//lamellipodium;GO:0030666//endocytic vesicle membrane;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005634//nucleus,"GO:0007067//mitotic nuclear division;GO:0009617//response to bacterium;GO:0051491//positive regulation of filopodium assembly;GO:0006928//cellular component movement;GO:0050999//regulation of nitric-oxide synthase activity;GO:0044281//small molecule metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0008154//actin polymerization or depolymerization;GO:0032880//regulation of protein localization;GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0034629//cellular protein complex localization;GO:0007411//axon guidance;GO:0030050//vesicle transport along actin filament;GO:0016050//vesicle organization;GO:0046209//nitric oxide metabolic process;GO:0051653//spindle localization;GO:2000370//positive regulation of clathrin-mediated endocytosis;GO:0006900//membrane budding;GO:0006351//transcription, DNA-templated",GO:0005083//small GTPase regulator activity;GO:0003779//actin binding;GO:0005515//protein binding,K05747//Pathogenic Escherichia coli infection;Adherens junction;Regulation of actin cytoskeleton;Fc gamma R-mediated phagocytosis;Shigellosis;Chemokine signaling pathway;Salmonella infection;Bacterial invasion of epithelial cells
89765,0,0,0,10,0,1,5,0,0,0,0,0,RSPH1;radial spoke head 1 homolog (Chlamydomonas),GO:0005634//nucleus;GO:0031514//motile cilium;GO:0005829//cytosol,GO:0007126//meiotic nuclear division;GO:0035082//axoneme assembly,-,K04575//Amyotrophic lateral sclerosis (ALS)
89766,0,25,0,0,0,51,57,50,42,131,0,0,UMODL1;uromodulin-like 1,GO:0005737//cytoplasm;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0007338//single fertilization;GO:0097211//cellular response to gonadotropin-releasing hormone;GO:2000354//regulation of ovarian follicle development;GO:0048609//multicellular organismal reproductive process;GO:0042981//regulation of apoptotic process;GO:0060612//adipose tissue development;GO:0010468//regulation of gene expression;GO:0010466//negative regulation of peptidase activity,GO:0005509//calcium ion binding;GO:0030414//peptidase inhibitor activity,K13912//Salivary secretion
89777,0,0,0,0,0,0,0,0,0,0,19,0,"SERPINB12;serpin peptidase inhibitor, clade B (ovalbumin), member 12",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0042177//negative regulation of protein catabolic process;GO:0002244//hematopoietic progenitor cell differentiation;GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0019899//enzyme binding;GO:0004867//serine-type endopeptidase inhibitor activity,-
89778,0,59,0,9,17,0,0,0,21,0,0,0,"SERPINB11;serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)",GO:0005737//cytoplasm;GO:0005615//extracellular space,GO:0010951//negative regulation of endopeptidase activity;GO:0030162//regulation of proteolysis,GO:0004867//serine-type endopeptidase inhibitor activity,-
89780,0,0,0,0,0,11,0,0,0,0,0,0,"WNT3A;wingless-type MMTV integration site family, member 3A",GO:0005578//proteinaceous extracellular matrix;GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0005615//extracellular space;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0005576//extracellular region,"GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0071300//cellular response to retinoic acid;GO:0030097//hemopoiesis;GO:0010387//COP9 signalosome assembly;GO:0001934//positive regulation of protein phosphorylation;GO:0048343//paraxial mesodermal cell fate commitment;GO:0061184//positive regulation of dermatome development;GO:0061317//canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment;GO:0001649//osteoblast differentiation;GO:0061098//positive regulation of protein tyrosine kinase activity;GO:0048337//positive regulation of mesodermal cell fate specification;GO:0021846//cell proliferation in forebrain;GO:0035413//positive regulation of catenin import into nucleus;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0032092//positive regulation of protein binding;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0070527//platelet aggregation;GO:0060021//palate development;GO:2000049//positive regulation of cell-cell adhesion mediated by cadherin;GO:2000081//positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation;GO:0042472//inner ear morphogenesis;GO:0008284//positive regulation of cell proliferation;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0035914//skeletal muscle cell differentiation;GO:0021874//Wnt signaling pathway involved in forebrain neuroblast division;GO:0036342//post-anal tail morphogenesis;GO:0021766//hippocampus development;GO:0034613//cellular protein localization;GO:0030182//neuron differentiation;GO:0050768//negative regulation of neurogenesis;GO:0002092//positive regulation of receptor internalization;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0030879//mammary gland development;GO:0021527//spinal cord association neuron differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0090245//axis elongation involved in somitogenesis;GO:0003136//negative regulation of heart induction by canonical Wnt signaling pathway;GO:0001947//heart looping;GO:0048697//positive regulation of collateral sprouting in absence of injury;GO:0060070//canonical Wnt signaling pathway;GO:0045599//negative regulation of fat cell differentiation;GO:0007411//axon guidance;GO:0001701//in utero embryonic development;GO:0021904//dorsal/ventral neural tube patterning;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030198//extracellular matrix organization;GO:0010977//negative regulation of neuron projection development;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0070507//regulation of microtubule cytoskeleton organization;GO:0030890//positive regulation of B cell proliferation",GO:0019904//protein domain specific binding;GO:0003713//transcription coactivator activity;GO:0005109//frizzled binding;GO:0005515//protein binding;GO:0048018//receptor agonist activity;GO:0005110//frizzled-2 binding,K00312//Basal cell carcinoma;Melanogenesis;Pathways in cancer;Hedgehog signaling pathway;Wnt signaling pathway;HTLV-I infection
89781,0,0,0,1,19,10,0,0,7,1,30,0,HPS4;Hermansky-Pudlak syndrome 4,GO:0016020//membrane;GO:0042470//melanosome;GO:0031085//BLOC-3 complex;GO:0042827//platelet dense granule;GO:0005764//lysosome;GO:0005737//cytoplasm,GO:0007040//lysosome organization;GO:0007596//blood coagulation;GO:0007599//hemostasis;GO:0048075//positive regulation of eye pigmentation;GO:0030318//melanocyte differentiation;GO:0050821//protein stabilization;GO:0006605//protein targeting,GO:0046983//protein dimerization activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,-
89782,92,0,0,4,18,37,0,0,78,0,10,0,LMLN;leishmanolysin-like (metallopeptidase M8 family),GO:0005737//cytoplasm;GO:0005925//focal adhesion;GO:0016020//membrane;GO:0005811//lipid particle,GO:0006508//proteolysis;GO:0007155//cell adhesion;GO:0007067//mitotic nuclear division,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
89790,0,0,0,0,0,0,18,0,58,0,27,0,SIGLEC10;sialic acid binding Ig-like lectin 10,GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
89792,0,1,44,0,0,0,3,0,0,0,0,0,GAL3ST3;galactose-3-O-sulfotransferase 3,GO:0032580//Golgi cisterna membrane;GO:0016021//integral component of membrane,GO:0009311//oligosaccharide metabolic process;GO:0005996//monosaccharide metabolic process;GO:0030309//poly-N-acetyllactosamine metabolic process;GO:0030166//proteoglycan biosynthetic process;GO:0006790//sulfur compound metabolic process,GO:0030246//carbohydrate binding;GO:0050698//proteoglycan sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity;GO:0050656//3'-phosphoadenosine 5'-phosphosulfate binding,-
89795,58,0,0,0,0,0,68,0,97,141,17,0,NAV3;neuron navigator 3,GO:0005640//nuclear outer membrane,-,-,K05699//Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Amoebiasis;Focal adhesion;Adherens junction
89796,8,15,1,0,1,58,0,18,77,143,48,0,NAV1;neuron navigator 1,GO:0005737//cytoplasm;GO:0005874//microtubule,GO:0001764//neuron migration;GO:0001578//microtubule bundle formation,-,K11447//Transcriptional misregulation in cancer;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
89797,120,0,0,0,0,48,197,65,61,159,30,372,NAV2;neuron navigator 2,GO:0005614//interstitial matrix;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0007608//sensory perception of smell;GO:0008152//metabolic process;GO:0021554//optic nerve development;GO:0021563//glossopharyngeal nerve development;GO:0007605//sensory perception of sound;GO:0007626//locomotory behavior;GO:0021564//vagus nerve development;GO:0003025//regulation of systemic arterial blood pressure by baroreceptor feedback,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0008201//heparin binding,K05699//Focal adhesion;Amoebiasis;Adherens junction;Regulation of actin cytoskeleton;Systemic lupus erythematosus;Leukocyte transendothelial migration;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);K06115//Tight junction;K04437//Focal adhesion;MAPK signaling pathway;Salmonella infection
898,0,0,0,0,0,0,1,0,23,0,0,0,CCNE1;cyclin E1,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0000307//cyclin-dependent protein kinase holoenzyme complex;GO:0005829//cytosol;GO:0005730//nucleolus,"GO:0006270//DNA replication initiation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000082//G1/S transition of mitotic cell cycle;GO:0051301//cell division;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0016055//Wnt signaling pathway",GO:0003713//transcription coactivator activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0016301//kinase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0050681//androgen receptor binding,K06626//Oocyte meiosis;Pathways in cancer;Cell cycle;Small cell lung cancer;p53 signaling pathway;Prostate cancer;Measles
89801,95,0,0,0,0,15,0,78,11,1,2,0,"PPP1R3F;protein phosphatase 1, regulatory subunit 3F",GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0005979//regulation of glycogen biosynthetic process;GO:2000465//regulation of glycogen (starch) synthase activity,GO:2001069//glycogen binding;GO:0019903//protein phosphatase binding,K07189//Insulin signaling pathway
89822,0,0,0,0,0,1,0,0,12,0,4,0,"KCNK17;potassium channel, subfamily K, member 17",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport,GO:0005244//voltage-gated ion channel activity;GO:0005267//potassium channel activity,-
89832,0,0,0,0,0,15,0,0,3,0,0,0,"CHRFAM7A;CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion",GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport,GO:0005230//extracellular ligand-gated ion channel activity,K04809//Nicotine addiction;Cholinergic synapse;Calcium signaling pathway;Neuroactive ligand-receptor interaction
89837,0,0,0,0,0,14,0,0,10,0,0,0,ULK4P3;ULK4 pseudogene 3,-,-,-,K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation
89839,0,0,0,0,0,0,0,0,12,0,0,0,ARHGAP11B;Rho GTPase activating protein 11B,GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K07526//Axon guidance
89845,119,0,0,0,0,11,62,0,11,42,0,0,"ABCC10;ATP-binding cassette, sub-family C (CFTR/MRP), member 10",GO:0005765//lysosomal membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process;GO:0055085//transmembrane transport,"GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005524//ATP binding",K05674//ABC transporters
89846,0,0,0,0,0,0,63,0,32,68,0,0,"FGD3;FYVE, RhoGEF and PH domain containing 3",GO:0030027//lamellipodium;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005829//cytosol;GO:0001726//ruffle;GO:0005794//Golgi apparatus,GO:0043547//positive regulation of GTPase activity;GO:0046847//filopodium assembly;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0043088//regulation of Cdc42 GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007010//cytoskeleton organization;GO:0008360//regulation of cell shape;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0030036//actin cytoskeleton organization,GO:0031267//small GTPase binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0005085//guanyl-nucleotide exchange factor activity,K05722//Regulation of actin cytoskeleton
89848,1,41,0,7,50,0,1,0,103,45,138,355,FCHSD1;FCH and double SH3 domains 1,-,-,-,K07526//Axon guidance
89849,0,0,0,0,0,0,23,23,1,0,0,0,ATG16L2;autophagy related 16-like 2 (S. cerevisiae),GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006914//autophagy;GO:0039689//negative stranded viral RNA replication;GO:0015031//protein transport,-,K12857//Spliceosome
8985,0,0,0,9,0,0,0,0,26,0,0,0,"PLOD3;procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3",GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0030867//rough endoplasmic reticulum membrane;GO:0005789//endoplasmic reticulum membrane,GO:0042311//vasodilation;GO:0055114//oxidation-reduction process;GO:0030199//collagen fibril organization;GO:0008104//protein localization;GO:0048730//epidermis morphogenesis;GO:0021915//neural tube development;GO:0030198//extracellular matrix organization;GO:0032870//cellular response to hormone stimulus;GO:0070831//basement membrane assembly;GO:0001701//in utero embryonic development;GO:0006464//cellular protein modification process;GO:0060425//lung morphogenesis;GO:0001886//endothelial cell morphogenesis,GO:0033823//procollagen glucosyltransferase activity;GO:0008475//procollagen-lysine 5-dioxygenase activity;GO:0005515//protein binding;GO:0005506//iron ion binding;GO:0031418//L-ascorbic acid binding;GO:0050211//procollagen galactosyltransferase activity,K13646//Other types of O-glycan biosynthesis;Lysine degradation
89853,0,0,0,0,11,5,64,29,6,0,6,0,MVB12B;multivesicular body subunit 12B,GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0005770//late endosome;GO:0031982//vesicle;GO:0005829//cytosol;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0000813//ESCRT I complex,GO:0042058//regulation of epidermal growth factor receptor signaling pathway;GO:0043162//ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0015031//protein transport,GO:0008289//lipid binding;GO:0043130//ubiquitin binding;GO:0005515//protein binding,K12186//Endocytosis
89857,0,0,0,0,0,0,0,0,70,0,0,424,KLHL6;kelch-like family member 6,-,GO:0002467//germinal center formation;GO:0050853//B cell receptor signaling pathway,-,-
89858,0,0,0,0,0,14,16,0,1,0,0,0,SIGLEC12;sialic acid binding Ig-like lectin 12 (gene/pseudogene),GO:0016021//integral component of membrane,GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
8986,0,0,1,0,0,0,0,0,0,0,0,0,"RPS6KA4;ribosomal protein S6 kinase, 90kDa, polypeptide 4",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007411//axon guidance;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0032793//positive regulation of CREB transcription factor activity;GO:0033129//positive regulation of histone phosphorylation;GO:0043988//histone H3-S28 phosphorylation;GO:0035066//positive regulation of histone acetylation;GO:0016572//histone phosphorylation;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0043987//histone H3-S10 phosphorylation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001818//negative regulation of cytokine production;GO:0070498//interleukin-1-mediated signaling pathway",GO:0004711//ribosomal protein S6 kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0048273//mitogen-activated protein kinase p38 binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,K04445//Bladder cancer;Neurotrophin signaling pathway;MAPK signaling pathway
89866,38,0,0,9,0,2,31,1,50,0,13,0,SEC16B;SEC16 homolog B (S. cerevisiae),GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0007031//peroxisome organization;GO:0070972//protein localization to endoplasmic reticulum;GO:0010628//positive regulation of gene expression;GO:0048208//COPII vesicle coating;GO:0016559//peroxisome fission;GO:0070863//positive regulation of protein exit from endoplasmic reticulum,-,-
89869,0,0,0,0,11,41,0,1,16,1,0,0,"PLCZ1;phospholipase C, zeta 1",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,GO:0007343//egg activation;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0007275//multicellular organismal development;GO:0016042//lipid catabolic process;GO:0006816//calcium ion transport;GO:0035556//intracellular signal transduction,GO:0004871//signal transducer activity;GO:0005509//calcium ion binding;GO:0004435//phosphatidylinositol phospholipase C activity,K05861//Inositol phosphate metabolism;Calcium signaling pathway;Oocyte meiosis;Metabolic pathways;Phosphatidylinositol signaling system
8987,0,0,0,3,40,0,0,41,0,0,11,0,STBD1;starch binding domain 1,GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0006936//muscle contraction,GO:0005515//protein binding;GO:2001070//starch binding,-
89872,112,0,0,0,0,0,17,0,0,0,7,0,AQP10;aquaporin 10,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0006833//water transport;GO:0009636//response to toxic substance;GO:0055085//transmembrane transport,GO:0005215//transporter activity,-
89874,0,53,156,294,290,0,33,406,178,0,329,46,"SLC25A21;solute carrier family 25 (mitochondrial oxoadipate carrier), member 21",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0034641//cellular nitrogen compound metabolic process;GO:0055085//transmembrane transport;GO:0044281//small molecule metabolic process;GO:0006554//lysine catabolic process,-,-
89876,29,0,0,6,16,0,0,0,54,0,0,0,"MAATS1;MYCBP-associated, testis expressed 1",GO:0005739//mitochondrion,-,GO:0005515//protein binding,-
8988,0,0,0,0,0,30,0,0,0,0,0,0,HSPB3;heat shock 27kDa protein 3,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006986//response to unfolded protein;GO:0008219//cell death,-,-
89882,0,1,0,0,0,0,0,0,0,0,0,0,TPD52L3;tumor protein D52-like 3,-,-,-,-
89883,0,0,0,0,0,0,0,0,19,0,0,0,"OR6W1P;olfactory receptor, family 6, subfamily W, member 1 pseudogene",-,-,-,K04257//Olfactory transduction
89884,0,0,0,0,20,0,0,0,14,0,10,2,LHX4;LIM homeobox 4,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0008045//motor neuron axon guidance;GO:0021526//medial motor column neuron differentiation;GO:0001890//placenta development;GO:0043066//negative regulation of apoptotic process;GO:0009887//organ morphogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0043565//sequence-specific DNA binding,-
89885,0,0,0,4,18,0,11,0,11,0,14,0,FATE1;fetal and adult testis expressed 1,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,-,-,-
89886,0,0,0,0,0,0,0,1,6,96,17,0,SLAMF9;SLAM family member 9,GO:0016021//integral component of membrane,-,GO:0004872//receptor activity,-
89887,0,0,0,0,0,15,0,53,19,0,17,0,ZNF628;zinc finger protein 628,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
8989,60,0,0,0,0,0,0,0,30,108,0,0,"TRPA1;transient receptor potential cation channel, subfamily A, member 1",GO:0005887//integral component of plasma membrane;GO:0032421//stereocilium bundle;GO:0005886//plasma membrane,GO:0050968//detection of chemical stimulus involved in sensory perception of pain;GO:0048265//response to pain;GO:0070588//calcium ion transmembrane transport;GO:0042542//response to hydrogen peroxide;GO:0055085//transmembrane transport;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0006811//ion transport;GO:0034220//ion transmembrane transport;GO:0009409//response to cold;GO:0050955//thermoception;GO:0042493//response to drug,GO:0005262//calcium channel activity;GO:0015267//channel activity,-
89890,0,42,0,14,45,0,30,0,22,0,0,0,KBTBD6;kelch repeat and BTB (POZ) domain containing 6,-,-,GO:0005515//protein binding,-
89891,0,0,0,0,2,0,1,1,7,0,0,0,WDR34;WD repeat domain 34,GO:0005930//axoneme;GO:0005814//centriole;GO:0036064//ciliary basal body,-,-,K10409//Huntington's disease;K10415//Vasopressin-regulated water reabsorption;Phagosome;Salmonella infection
89894,0,0,0,0,2,14,17,0,0,0,0,0,TMEM116;transmembrane protein 116,GO:0016021//integral component of membrane,-,-,-
899,0,37,0,5,18,0,0,130,30,0,42,0,CCNF;cyclin F,GO:0005814//centriole;GO:0019005//SCF ubiquitin ligase complex;GO:0005634//nucleus,GO:0007067//mitotic nuclear division;GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0010826//negative regulation of centrosome duplication;GO:0001890//placenta development;GO:0016567//protein ubiquitination;GO:0000320//re-entry into mitotic cell cycle,GO:0005515//protein binding,-
8991,0,0,0,4,1,0,0,0,2,0,0,0,SELENBP1;selenium binding protein 1,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005615//extracellular space;GO:0005829//cytosol,GO:0015031//protein transport,GO:0005515//protein binding;GO:0008430//selenium binding,-
89910,0,2,0,2,122,0,5,0,68,0,1,32,UBE3B;ubiquitin protein ligase E3B,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K10588//Ubiquitin mediated proteolysis
8992,0,0,0,0,48,15,0,0,0,0,0,0,"ATP6V0E1;ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1","GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0010008//endosome membrane;GO:0030670//phagocytic vesicle membrane;GO:0033179//proton-transporting V-type ATPase, V0 domain",GO:0015992//proton transport;GO:0007035//vacuolar acidification;GO:0043200//response to amino acid;GO:0008152//metabolic process;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0016049//cell growth;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport,"GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0005215//transporter activity",K02153//Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Synaptic vesicle cycle;Metabolic pathways;Oxidative phosphorylation;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection
89927,43,0,0,0,0,9,20,57,13,6,5,0,C16orf45;chromosome 16 open reading frame 45,-,-,-,-
89932,0,23,0,11,9,0,0,0,17,0,16,0,"PAPLN;papilin, proteoglycan-like sulfated glycoprotein",GO:0005604//basement membrane,GO:0006508//proteolysis;GO:0010951//negative regulation of endopeptidase activity,GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0004867//serine-type endopeptidase inhibitor activity,-
8994,1,48,0,28,97,11,0,54,28,0,11,0,LIMD1;LIM domains containing 1,GO:0005925//focal adhesion;GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0016442//RISC complex,"GO:0002076//osteoblast development;GO:0007275//multicellular organismal development;GO:0045668//negative regulation of osteoblast differentiation;GO:0001666//response to hypoxia;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0016310//phosphorylation;GO:0016477//cell migration;GO:0007010//cytoskeleton organization;GO:0033962//cytoplasmic mRNA processing body assembly;GO:0008360//regulation of cell shape;GO:0006351//transcription, DNA-templated;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0035331//negative regulation of hippo signaling;GO:2000637//positive regulation of gene silencing by miRNA;GO:0006355//regulation of transcription, DNA-templated;GO:0035195//gene silencing by miRNA",GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003714//transcription corepressor activity,K12792//NOD-like receptor signaling pathway
89941,106,0,0,5,0,23,0,0,25,0,2,0,RHOT2;ras homolog family member T2,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0016020//membrane;GO:0031307//integral component of mitochondrial outer membrane,GO:0019725//cellular homeostasis;GO:0097345//mitochondrial outer membrane permeabilization;GO:0047497//mitochondrion transport along microtubule;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005509//calcium ion binding;GO:0005515//protein binding,-
89944,107,0,0,9,0,0,32,47,70,58,26,0,"GLB1L2;galactosidase, beta 1-like 2",GO:0005576//extracellular region,GO:0005975//carbohydrate metabolic process,GO:0004565//beta-galactosidase activity,K12309//Lysosome;Sphingolipid metabolism;Other glycan degradation;Galactose metabolism;Glycosphingolipid biosynthesis - ganglio series;Glycosaminoglycan degradation;Metabolic pathways
89953,80,31,24,19,37,6,8,0,27,20,0,0,KLC4;kinesin light chain 4,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005871//kinesin complex,GO:0008152//metabolic process,GO:0003777//microtubule motor activity,K10407//Salmonella infection
89958,0,0,0,0,22,0,25,0,0,0,0,0,SAPCD2;suppressor APC domain containing 2,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,K15542//mRNA surveillance pathway;K01509//Purine metabolism
8996,0,0,1,15,25,0,51,0,8,0,6,0,NOL3;nucleolar protein 3 (apoptosis repressor with CARD domain),GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0016528//sarcoplasm;GO:0005730//nucleolus,GO:0043066//negative regulation of apoptotic process;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0006915//apoptotic process;GO:0001666//response to hypoxia;GO:0010468//regulation of gene expression,GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0003723//RNA binding,-
8997,230,0,0,0,0,50,116,114,77,0,2,48,"KALRN;kalirin, RhoGEF kinase",GO:0070062//extracellular vesicular exosome;GO:0015629//actin cytoskeleton;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0007165//signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0016192//vesicle-mediated transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0035556//intracellular signal transduction,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
89970,0,18,1,0,24,11,0,0,7,0,0,0,RSPRY1;ring finger and SPRY domain containing 1,GO:0005576//extracellular region,-,GO:0008270//zinc ion binding,-
89978,0,0,0,1,0,12,4,0,12,0,0,0,DPH6;diphthamine biosynthesis 6,-,GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine,GO:0005524//ATP binding;GO:0017178//diphthine-ammonia ligase activity,-
8999,187,0,0,0,0,0,21,0,31,0,0,0,CDKL2;cyclin-dependent kinase-like 2 (CDC2-related kinase),GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007548//sex differentiation;GO:0051726//regulation of cell cycle;GO:0006468//protein phosphorylation;GO:0007165//signal transduction,GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004672//protein kinase activity,-
9,0,23,2,7,23,0,0,0,19,0,0,0,NAT1;N-acetyltransferase 1 (arylamine N-acetyltransferase),GO:0005829//cytosol,GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process,GO:0004060//arylamine N-acetyltransferase activity,K00622//Microbial metabolism in diverse environments;Metabolic pathways;Caffeine metabolism;Biosynthesis of secondary metabolites;Nitrotoluene degradation;Drug metabolism - other enzymes
90,0,0,1,0,3,0,17,28,25,0,6,562,"ACVR1;activin A receptor, type I",GO:0005887//integral component of plasma membrane;GO:0045177//apical part of cell;GO:0048179//activin receptor complex,"GO:0061445//endocardial cushion cell fate commitment;GO:0003143//embryonic heart tube morphogenesis;GO:0007281//germ cell development;GO:0060037//pharyngeal system development;GO:0001701//in utero embryonic development;GO:0001707//mesoderm formation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0032924//activin receptor signaling pathway;GO:0045669//positive regulation of osteoblast differentiation;GO:0030278//regulation of ossification;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0001655//urogenital system development;GO:0060923//cardiac muscle cell fate commitment;GO:0048641//regulation of skeletal muscle tissue development;GO:0030509//BMP signaling pathway;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0003289//atrial septum primum morphogenesis;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0018107//peptidyl-threonine phosphorylation;GO:0009968//negative regulation of signal transduction;GO:0001755//neural crest cell migration;GO:0000082//G1/S transition of mitotic cell cycle;GO:2000017//positive regulation of determination of dorsal identity;GO:0002526//acute inflammatory response;GO:0003183//mitral valve morphogenesis;GO:0001569//patterning of blood vessels;GO:0001702//gastrulation with mouth forming second;GO:0007368//determination of left/right symmetry;GO:0071385//cellular response to glucocorticoid stimulus;GO:0051145//smooth muscle cell differentiation;GO:0023014//signal transduction by phosphorylation;GO:0030501//positive regulation of bone mineralization","GO:0004672//protein kinase activity;GO:0050431//transforming growth factor beta binding;GO:0005524//ATP binding;GO:0016361//activin receptor activity, type I;GO:0046332//SMAD binding;GO:0017046//peptide hormone binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0042803//protein homodimerization activity;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0005515//protein binding;GO:0005025//transforming growth factor beta receptor activity, type I",K04675//TGF-beta signaling pathway;Cytokine-cytokine receptor interaction
900,0,0,0,30,159,0,0,0,19,0,0,0,CCNG1;cyclin G1,GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0043025//neuronal cell body;GO:0030425//dendrite,GO:0006949//syncytium formation;GO:0043066//negative regulation of apoptotic process;GO:0007420//brain development;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007067//mitotic nuclear division;GO:0010243//response to organonitrogen compound;GO:0016049//cell growth;GO:0007095//mitotic G2 DNA damage checkpoint,GO:0019904//protein domain specific binding;GO:0005515//protein binding,K10145//p53 signaling pathway
90007,7,0,0,0,0,0,0,0,0,0,0,0,MIDN;midnolin,GO:0005730//nucleolus;GO:0005829//cytosol,-,-,-
9001,70,0,0,0,0,0,0,124,29,0,9,0,HAP1;huntingtin-associated protein 1,GO:0016234//inclusion body;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0015629//actin cytoskeleton;GO:0005856//cytoskeleton,"GO:0017157//regulation of exocytosis;GO:0031587//positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity;GO:0045742//positive regulation of epidermal growth factor receptor signaling pathway;GO:1902430//negative regulation of beta-amyloid formation;GO:0007420//brain development;GO:0007268//synaptic transmission;GO:0047496//vesicle transport along microtubule;GO:0008104//protein localization;GO:1902513//regulation of organelle transport along microtubule;GO:0008090//retrograde axon cargo transport;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0032230//positive regulation of synaptic transmission, GABAergic;GO:0008089//anterograde axon cargo transport",GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0048403//brain-derived neurotrophic factor binding,K04647//GABAergic synapse;Huntington's disease
90011,0,0,0,0,0,41,0,0,0,0,0,0,"KIR3DX1;killer cell immunoglobulin-like receptor, three domains, X1",GO:0005576//extracellular region,-,-,K07981//Antigen processing and presentation;Graft-versus-host disease;Natural killer cell mediated cytotoxicity;K07980//Antigen processing and presentation;Natural killer cell mediated cytotoxicity;Graft-versus-host disease
90019,0,0,0,0,0,0,0,0,15,0,0,0,SYT8;synaptotagmin VIII,GO:0008021//synaptic vesicle;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0005886//plasma membrane,GO:0007340//acrosome reaction,GO:0005215//transporter activity;GO:0048306//calcium-dependent protein binding,K15290//Synaptic vesicle cycle
9002,0,0,0,0,0,0,0,0,0,70,0,286,F2RL3;coagulation factor II (thrombin) receptor-like 3,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0030168//platelet activation;GO:0070493//thrombin receptor signaling pathway;GO:0009611//response to wounding;GO:0007165//signal transduction;GO:0007596//blood coagulation;GO:0007200//phospholipase C-activating G-protein coupled receptor signaling pathway;GO:0060155//platelet dense granule organization,GO:0015057//thrombin receptor activity,K04236//Neuroactive ligand-receptor interaction
90024,0,30,0,23,16,0,0,146,15,0,41,0,FLJ20021;uncharacterized LOC90024,-,-,-,-
90025,36,1,0,0,0,10,0,0,24,0,0,0,UBE3D;ubiquitin protein ligase E3D,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination,GO:0016874//ligase activity,K12584//RNA degradation
90050,0,0,0,0,0,14,0,0,8,1,20,0,"FAM181A;family with sequence similarity 181, member A",-,-,-,-
90060,96,0,0,0,5,11,19,71,6,0,5,0,CCDC120;coiled-coil domain containing 120,-,-,-,K12817//Spliceosome;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
90070,0,0,0,0,0,0,0,0,15,0,0,0,LACRT;lacritin,GO:0005576//extracellular region;GO:0005615//extracellular space;GO:0030141//secretory granule,GO:0050679//positive regulation of epithelial cell proliferation;GO:0033173//calcineurin-NFAT signaling cascade;GO:0051047//positive regulation of secretion;GO:0051533//positive regulation of NFAT protein import into nucleus;GO:0034067//protein localization to Golgi apparatus;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0070075//tear secretion;GO:0019722//calcium-mediated signaling;GO:0008284//positive regulation of cell proliferation;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol,GO:0008083//growth factor activity;GO:0001968//fibronectin binding;GO:0043237//laminin-1 binding;GO:0001948//glycoprotein binding;GO:0047485//protein N-terminus binding;GO:0005518//collagen binding,-
90075,0,0,53,0,0,25,0,0,0,0,14,0,ZNF30;zinc finger protein 30,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
901,0,23,1,50,254,32,55,0,18,249,0,0,CCNG2;cyclin G2,GO:0005737//cytoplasm,GO:0000075//cell cycle checkpoint;GO:0007067//mitotic nuclear division;GO:0051726//regulation of cell cycle,-,K10146//p53 signaling pathway
90102,0,14,0,0,13,12,0,64,101,35,0,0,"PHLDB2;pleckstrin homology-like domain, family B, member 2",GO:0005886//plasma membrane;GO:0045111//intermediate filament cytoskeleton;GO:0005737//cytoplasm,-,GO:0005515//protein binding,K12229//B cell receptor signaling pathway;K10866//Non-homologous end-joining;Homologous recombination;K12559//Fc gamma R-mediated phagocytosis;K12478//Tuberculosis;Phagosome;Endocytosis
90113,0,0,0,0,0,26,2,0,26,0,50,0,VWA5B2;von Willebrand factor A domain containing 5B2,-,-,-,K10798//Base excision repair;NF-kappa B signaling pathway
90120,0,0,0,0,1,0,0,0,17,128,12,0,C9orf69;chromosome 9 open reading frame 69,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0016021//integral component of membrane,GO:0008284//positive regulation of cell proliferation;GO:0048524//positive regulation of viral process;GO:0016032//viral process;GO:0007049//cell cycle,GO:0005525//GTP binding;GO:0005515//protein binding,-
90121,0,0,0,9,69,0,0,0,29,0,0,0,"TSR2;TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)",-,GO:0006364//rRNA processing,GO:0005515//protein binding,-
9013,0,0,0,0,0,0,40,0,20,188,9,389,"TAF1C;TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa",GO:0005654//nucleoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0010467//gene expression;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription",GO:0003677//DNA binding;GO:0005515//protein binding,-
90134,0,0,0,0,13,0,0,0,32,0,0,0,"KCNH7;potassium voltage-gated channel, subfamily H (eag-related), member 7",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0042391//regulation of membrane potential;GO:0051291//protein heterooligomerization;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0007623//circadian rhythm;GO:0071805//potassium ion transmembrane transport;GO:0007165//signal transduction,GO:0005249//voltage-gated potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:0004871//signal transducer activity,-
90135,4,0,1,7,23,0,0,0,17,0,0,0,BTBD6;BTB (POZ) domain containing 6,GO:0000932//cytoplasmic mRNA processing body,-,-,-
90139,20,0,0,15,13,0,16,97,14,0,5,0,TSPAN18;tetraspanin 18,GO:0016021//integral component of membrane,-,-,K06509//p53 signaling pathway
9014,0,0,0,35,21,0,0,0,7,0,1,0,"TAF1B;TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa",GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0001189//RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript;GO:0006351//transcription, DNA-templated;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0006360//transcription from RNA polymerase I promoter",GO:0017025//TBP-class protein binding;GO:0001187//RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity;GO:0046872//metal ion binding;GO:0001164//RNA polymerase I CORE element sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
90141,0,0,36,15,23,0,0,4,15,10,0,0,EFCAB11;EF-hand calcium binding domain 11,-,-,GO:0005509//calcium ion binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
9015,0,0,0,0,27,0,0,0,0,0,0,0,"TAF1A;TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa",GO:0043231//intracellular membrane-bounded organelle;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0000120//RNA polymerase I transcription factor complex;GO:0005654//nucleoplasm,"GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006366//transcription from RNA polymerase II promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0010467//gene expression;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0005515//protein binding,-
9016,0,0,0,0,0,0,41,0,6,0,0,0,"SLC25A14;solute carrier family 25 (mitochondrial carrier, brain), member 14",GO:0005887//integral component of plasma membrane;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion,GO:0006810//transport;GO:0006839//mitochondrial transport;GO:0009060//aerobic respiration,-,-
90161,24,0,0,0,0,0,71,38,9,0,0,0,HS6ST2;heparan sulfate 6-O-sulfotransferase 2,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome,"GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0005975//carbohydrate metabolic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification",-,K08102//Glycosaminoglycan biosynthesis - heparan sulfate
90167,54,0,0,0,0,37,47,0,11,0,0,0,FRMD7;FERM domain containing 7,GO:0005615//extracellular space;GO:0043005//neuron projection;GO:0005856//cytoskeleton;GO:0030426//growth cone;GO:0043025//neuronal cell body,GO:0010975//regulation of neuron projection development,-,K06082//Adherens junction
90187,207,0,80,20,46,13,34,137,24,0,52,2,EMILIN3;elastin microfibril interfacer 3,GO:0031012//extracellular matrix;GO:0005737//cytoplasm;GO:0005578//proteinaceous extracellular matrix,-,-,K14000//Protein processing in endoplasmic reticulum
9019,0,0,0,6,11,31,0,0,72,0,0,0,MPZL1;myelin protein zero-like 1,GO:0009986//cell surface;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007267//cell-cell signaling,GO:0005198//structural molecule activity;GO:0005515//protein binding,K06770//Cell adhesion molecules (CAMs)
90196,195,35,29,4,0,0,0,0,19,1,0,0,SYS1;Sys1 golgi trafficking protein,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0015031//protein transport,-,-
90199,0,0,0,0,0,0,38,0,33,0,0,0,WFDC8;WAP four-disulfide core domain 8,GO:0005576//extracellular region,GO:0010951//negative regulation of endopeptidase activity,GO:0004867//serine-type endopeptidase inhibitor activity,K03909//Complement and coagulation cascades;K15619//Transcriptional misregulation in cancer;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
902,5,0,0,12,12,9,0,0,0,0,21,0,CCNH;cyclin H,GO:0005730//nucleolus;GO:0070985//TFIIK complex;GO:0005654//nucleoplasm;GO:0019907//cyclin-dependent protein kinase activating kinase holoenzyme complex;GO:0005675//holo TFIIH complex;GO:0005634//nucleus,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006363//termination of RNA polymerase I transcription;GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006370//7-methylguanosine mRNA capping;GO:0006281//DNA repair;GO:0006200//ATP catabolic process;GO:0050434//positive regulation of viral transcription;GO:0006289//nucleotide-excision repair;GO:0006366//transcription from RNA polymerase II promoter;GO:0000718//nucleotide-excision repair, DNA damage removal;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006468//protein phosphorylation;GO:0006283//transcription-coupled nucleotide-excision repair",GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0008094//DNA-dependent ATPase activity,K06634//Basal transcription factors;Nucleotide excision repair;Cell cycle
9020,183,148,66,46,104,1,81,147,43,1,198,650,MAP3K14;mitogen-activated protein kinase kinase kinase 14,GO:0005829//cytosol,GO:0071260//cellular response to mechanical stimulus;GO:0006468//protein phosphorylation;GO:0000165//MAPK cascade;GO:0000186//activation of MAPKK activity;GO:0006955//immune response;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0031295//T cell costimulation;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0038061//NIK/NF-kappaB signaling,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004704//NF-kappaB-inducing kinase activity;GO:0005524//ATP binding,K04466//T cell receptor signaling pathway;Osteoclast differentiation;Apoptosis;MAPK signaling pathway;Epithelial cell signaling in Helicobacter pylori infection;Epstein-Barr virus infection;HTLV-I infection;NF-kappa B signaling pathway;Intestinal immune network for IgA production
90203,2,96,110,55,95,13,46,294,85,0,432,1,SNX21;sorting nexin family member 21,GO:0030659//cytoplasmic vesicle membrane,GO:0015031//protein transport,GO:0035091//phosphatidylinositol binding,K11992//Primary bile acid biosynthesis;Metabolic pathways;Peroxisome
90204,0,1,19,0,20,1,44,0,5,0,0,0,"ZSWIM1;zinc finger, SWIM-type containing 1",GO:0005634//nucleus,-,GO:0008270//zinc ion binding,K11447//Transcriptional misregulation in cancer;K00797//Metabolic pathways;beta-Alanine metabolism;Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
9021,89,0,0,0,0,0,1,0,0,4,2,0,SOCS3;suppressor of cytokine signaling 3,GO:0005829//cytosol,GO:0006469//negative regulation of protein kinase activity;GO:0060670//branching involved in labyrinthine layer morphogenesis;GO:0060707//trophoblast giant cell differentiation;GO:0060397//JAK-STAT cascade involved in growth hormone signaling pathway;GO:0060708//spongiotrophoblast differentiation;GO:0016567//protein ubiquitination;GO:0043066//negative regulation of apoptotic process;GO:0040008//regulation of growth;GO:0007259//JAK-STAT cascade;GO:0046627//negative regulation of insulin receptor signaling pathway;GO:0060334//regulation of interferon-gamma-mediated signaling pathway;GO:0060337//type I interferon signaling pathway;GO:0060338//regulation of type I interferon-mediated signaling pathway;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0045597//positive regulation of cell differentiation;GO:0060674//placenta blood vessel development,GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity,K04696//Herpes simplex infection;Adipocytokine signaling pathway;Osteoclast differentiation;Hepatitis C;Type II diabetes mellitus;Insulin signaling pathway;Jak-STAT signaling pathway;Influenza A;Ubiquitin mediated proteolysis
9022,0,0,0,0,0,0,0,0,14,0,0,0,CLIC3;chloride intracellular channel 3,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0034707//chloride channel complex;GO:0070062//extracellular vesicular exosome,GO:1902476//chloride transmembrane transport;GO:0007165//signal transduction;GO:0034765//regulation of ion transmembrane transport;GO:0006821//chloride transport;GO:0044070//regulation of anion transport,GO:0005247//voltage-gated chloride channel activity;GO:0005515//protein binding;GO:0005254//chloride channel activity,-
90226,0,0,0,0,0,38,11,0,0,0,4,0,UCN2;urocortin 2,GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0071456//cellular response to hypoxia;GO:0006171//cAMP biosynthetic process;GO:0071385//cellular response to glucocorticoid stimulus;GO:0007586//digestion;GO:0010629//negative regulation of gene expression;GO:0046882//negative regulation of follicle-stimulating hormone secretion;GO:0006950//response to stress;GO:0033685//negative regulation of luteinizing hormone secretion;GO:0008283//cell proliferation,GO:0005179//hormone activity;GO:0042562//hormone binding;GO:0005102//receptor binding,-
9023,0,0,0,0,0,0,0,0,19,0,0,0,CH25H;cholesterol 25-hydroxylase,GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane,GO:0008203//cholesterol metabolic process;GO:0006699//bile acid biosynthetic process;GO:0008206//bile acid metabolic process;GO:0055114//oxidation-reduction process;GO:0044281//small molecule metabolic process;GO:0016126//sterol biosynthetic process;GO:0006629//lipid metabolic process;GO:0006633//fatty acid biosynthetic process,GO:0001567//cholesterol 25-hydroxylase activity;GO:0008395//steroid hydroxylase activity;GO:0005506//iron ion binding,K10223//Primary bile acid biosynthesis
90231,0,0,0,0,0,0,12,1,12,0,0,0,KIAA2013;KIAA2013,GO:0016021//integral component of membrane;GO:0016020//membrane,-,-,-
90233,0,0,5,0,29,1,0,124,46,0,0,0,ZNF551;zinc finger protein 551,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9024,0,0,26,0,0,10,151,0,49,0,12,216,BRSK2;BR serine/threonine kinase 2,GO:0048471//perinuclear region of cytoplasm;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum,GO:0030010//establishment of cell polarity;GO:0007067//mitotic nuclear division;GO:0007409//axonogenesis;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0018105//peptidyl-serine phosphorylation;GO:0006887//exocytosis;GO:0030182//neuron differentiation;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0000086//G2/M transition of mitotic cell cycle;GO:0031532//actin cytoskeleton reorganization;GO:0006468//protein phosphorylation,GO:0050321//tau-protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0019901//protein kinase binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
90249,0,0,0,0,0,0,0,0,7,0,8,0,UNC5A;unc-5 homolog A (C. elegans),GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0042981//regulation of apoptotic process;GO:0033564//anterior/posterior axon guidance;GO:0006915//apoptotic process;GO:0043065//positive regulation of apoptotic process;GO:0007411//axon guidance;GO:0007165//signal transduction,-,K07521//Axon guidance
9025,0,1,0,0,6,17,34,0,47,0,8,0,"RNF8;ring finger protein 8, E3 ubiquitin protein ligase","GO:0030496//midbody;GO:0035861//site of double-strand break;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0000151//ubiquitin ligase complex;GO:0000781//chromosome, telomeric region",GO:0070534//protein K63-linked ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0033522//histone H2A ubiquitination;GO:0006303//double-strand break repair via nonhomologous end joining;GO:0033523//histone H2B ubiquitination;GO:0006302//double-strand break repair;GO:0045900//negative regulation of translational elongation;GO:0007067//mitotic nuclear division;GO:0006974//cellular response to DNA damage stimulus;GO:0007286//spermatid development;GO:0036297//interstrand cross-link repair;GO:0045739//positive regulation of DNA repair;GO:0045190//isotype switching;GO:0010212//response to ionizing radiation;GO:0070535//histone H2A K63-linked ubiquitination;GO:0043486//histone exchange;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051865//protein autoubiquitination,GO:0008270//zinc ion binding;GO:0042803//protein homodimerization activity;GO:0042393//histone binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0016881//acid-amino acid ligase activity;GO:0031625//ubiquitin protein ligase binding;GO:0003682//chromatin binding,-
9026,105,0,0,5,12,1,41,0,57,0,22,435,HIP1R;huntingtin interacting protein 1 related,GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0005905//coated pit;GO:0030665//clathrin-coated vesicle membrane;GO:0030136//clathrin-coated vesicle;GO:0043231//intracellular membrane-bounded organelle,GO:0006898//receptor-mediated endocytosis,GO:0003779//actin binding;GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding,K04559//Huntington's disease
90268,0,0,1,40,24,51,8,65,39,0,0,1,OTULIN;OTU deubiquitinase with linear linkage specificity,GO:0005737//cytoplasm;GO:0071797//LUBAC complex,GO:0050728//negative regulation of inflammatory response;GO:0006508//proteolysis;GO:0060070//canonical Wnt signaling pathway;GO:0070431//nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0045087//innate immune response;GO:1990108//protein linear deubiquitination;GO:0002040//sprouting angiogenesis,GO:0004843//ubiquitin-specific protease activity;GO:0008234//cysteine-type peptidase activity;GO:0005515//protein binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K01875//Arginine and proline metabolism;Biotin metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K06264//ECM-receptor interaction
9027,0,0,0,0,0,0,0,0,5,189,27,0,"NAT8;N-acetyltransferase 8 (GCN5-related, putative)",GO:0016021//integral component of membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0070062//extracellular vesicular exosome;GO:0005789//endoplasmic reticulum membrane;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0007369//gastrulation;GO:0042493//response to drug;GO:0006749//glutathione metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0050435//beta-amyloid metabolic process;GO:0010628//positive regulation of gene expression,"GO:0004468//lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0005515//protein binding",-
90271,94,0,0,0,17,11,0,0,9,0,0,0,LINC00263;long intergenic non-protein coding RNA 263,-,-,-,-
90273,0,0,0,0,0,0,0,0,2,0,0,0,CEACAM21;carcinoembryonic antigen-related cell adhesion molecule 21,GO:0016021//integral component of membrane,-,-,-
90288,178,0,0,0,0,0,0,0,9,0,0,0,EFCAB12;EF-hand calcium binding domain 12,-,-,GO:0005509//calcium ion binding,-
90293,0,0,0,0,21,0,0,0,62,0,15,0,KLHL13;kelch-like family member 13,GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0007067//mitotic nuclear division;GO:0016567//protein ubiquitination;GO:0000910//cytokinesis,GO:0004842//ubiquitin-protein transferase activity,K10447//Ubiquitin mediated proteolysis
9031,180,38,0,66,212,1,20,0,11,0,0,0,"BAZ1B;bromodomain adjacent to zinc finger domain, 1B",GO:0043596//nuclear replication fork;GO:0005721//pericentric heterochromatin;GO:0000793//condensed chromosome,"GO:0006351//transcription, DNA-templated;GO:0006333//chromatin assembly or disassembly;GO:0048096//chromatin-mediated maintenance of transcription;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0006974//cellular response to DNA damage stimulus;GO:0006302//double-strand break repair;GO:0003007//heart morphogenesis;GO:2000273//positive regulation of receptor activity;GO:0016572//histone phosphorylation;GO:0006355//regulation of transcription, DNA-templated",GO:0071884//vitamin D receptor activator activity;GO:0003682//chromatin binding;GO:0035173//histone kinase activity;GO:0005524//ATP binding;GO:0070577//lysine-acetylated histone binding;GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004713//protein tyrosine kinase activity,-
90316,0,0,0,0,0,0,0,0,2,0,0,0,"TGIF2LX;TGFB-induced factor homeobox 2-like, X-linked",GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding,K15613//Transcriptional misregulation in cancer
90317,0,0,45,19,98,13,35,0,33,0,0,0,ZNF616;zinc finger protein 616,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
90321,0,0,0,14,4,12,0,0,35,0,0,0,ZNF766;zinc finger protein 766,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
90324,0,0,2,0,6,34,0,0,18,0,1,0,CCDC97;coiled-coil domain containing 97,-,-,-,-
90326,2,305,62,195,563,1,45,506,181,0,760,539,"THAP3;THAP domain containing, apoptosis associated protein 3",-,-,GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
9033,174,0,0,0,0,0,18,0,45,0,0,0,PKD2L1;polycystic kidney disease 2-like 1,GO:0043231//intracellular membrane-bounded organelle;GO:0034704//calcium channel complex;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0031513//nonmotile primary cilium;GO:0060170//ciliary membrane,GO:0071805//potassium ion transmembrane transport;GO:0035725//sodium ion transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0006812//cation transport;GO:0071468//cellular response to acidic pH;GO:0070207//protein homotrimerization;GO:0050915//sensory perception of sour taste;GO:0050982//detection of mechanical stimulus;GO:0001581//detection of chemical stimulus involved in sensory perception of sour taste;GO:0007224//smoothened signaling pathway,GO:0051371//muscle alpha-actinin binding;GO:0005261//cation channel activity;GO:0008092//cytoskeletal protein binding;GO:0005509//calcium ion binding;GO:0008324//cation transmembrane transporter activity;GO:0005227//calcium activated cation channel activity;GO:0015269//calcium-activated potassium channel activity;GO:0005515//protein binding;GO:0005262//calcium channel activity;GO:0051393//alpha-actinin binding;GO:0033040//sour taste receptor activity;GO:0005272//sodium channel activity;GO:0042802//identical protein binding,-
90332,81,0,0,0,0,0,0,0,22,0,0,0,EXOC3L2;exocyst complex component 3-like 2,GO:0000145//exocyst,GO:0006887//exocytosis,-,K06110//Tight junction
90333,0,0,0,25,8,20,0,0,20,0,0,0,ZNF468;zinc finger protein 468,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
90338,0,33,0,1,53,0,0,0,65,0,0,0,ZNF160;zinc finger protein 160,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0030097//hemopoiesis;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9034,0,0,0,0,0,0,0,0,6,0,0,0,CCRL2;chemokine (C-C motif) receptor-like 2,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0006935//chemotaxis;GO:0070098//chemokine-mediated signaling pathway;GO:0006954//inflammatory response,GO:0042379//chemokine receptor binding;GO:0004950//chemokine receptor activity;GO:0048020//CCR chemokine receptor binding,-
90342,0,0,1,0,0,23,1,145,99,0,44,0,FER1L5;fer-1-like family member 5,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,-
90353,80,0,0,2,0,26,0,0,0,0,0,0,CTU1;cytosolic thiouridylase subunit 1,GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0032447//protein urmylation;GO:0002098//tRNA wobble uridine modification;GO:0034227//tRNA thio-modification,GO:0005515//protein binding;GO:0016779//nucleotidyltransferase activity;GO:0000049//tRNA binding,K14168//Sulfur relay system
90355,0,0,0,1,54,0,15,19,32,0,0,0,C5orf30;chromosome 5 open reading frame 30,GO:0005737//cytoplasm;GO:0035869//ciliary transition zone,GO:0015031//protein transport;GO:0060271//cilium morphogenesis,GO:0005515//protein binding,-
90362,0,1,0,16,34,0,0,0,11,0,0,0,"FAM110B;family with sequence similarity 110, member B",GO:0005737//cytoplasm;GO:0005815//microtubule organizing center,-,-,-
9037,0,0,0,0,0,35,35,1,64,0,25,0,"SEMA5A;sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0001938//positive regulation of endothelial cell proliferation;GO:2000352//negative regulation of endothelial cell apoptotic process;GO:0007411//axon guidance;GO:0035413//positive regulation of catenin import into nucleus;GO:1990256//signal clustering;GO:0060326//cell chemotaxis;GO:0050918//positive chemotaxis;GO:0051897//positive regulation of protein kinase B signaling;GO:0007267//cell-cell signaling;GO:0045766//positive regulation of angiogenesis;GO:0048843//negative regulation of axon extension involved in axon guidance;GO:0007413//axonal fasciculation;GO:0007155//cell adhesion;GO:0021536//diencephalon development;GO:0007399//nervous system development;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007162//negative regulation of cell adhesion;GO:0048842//positive regulation of axon extension involved in axon guidance;GO:0001569//patterning of blood vessels;GO:2001028//positive regulation of endothelial cell chemotaxis;GO:0030836//positive regulation of actin filament depolymerization,GO:0045545//syndecan binding;GO:0035373//chondroitin sulfate proteoglycan binding;GO:0043395//heparan sulfate proteoglycan binding;GO:0030215//semaphorin receptor binding;GO:0008046//axon guidance receptor activity,K06841//Axon guidance
90378,0,0,1,0,0,0,0,1,1,0,0,0,SAMD1;sterile alpha motif domain containing 1,GO:0005737//cytoplasm;GO:0005576//extracellular region,-,-,-
90379,0,0,0,0,0,16,24,0,13,0,0,0,DCAF15;DDB1 and CUL4 associated factor 15,-,GO:0016567//protein ubiquitination,-,-
90381,0,0,33,39,33,13,21,100,50,0,128,0,TICRR;TOPBP1-interacting checkpoint and replication regulator,GO:0005730//nucleolus;GO:0005634//nucleus,GO:0006281//DNA repair;GO:0030174//regulation of DNA-dependent DNA replication initiation;GO:0010212//response to ionizing radiation;GO:0006260//DNA replication;GO:0033314//mitotic DNA replication checkpoint;GO:0001731//formation of translation preinitiation complex;GO:0000075//cell cycle checkpoint,GO:0005515//protein binding;GO:0003682//chromatin binding,K04574//Amyotrophic lateral sclerosis (ALS);K13171//mRNA surveillance pathway;RNA transport
9039,0,0,0,3,8,0,0,29,77,0,0,0,UBA3;ubiquitin-like modifier activating enzyme 3,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006464//cellular protein modification process;GO:0007113//endomitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0045116//protein neddylation;GO:0006508//proteolysis,GO:0019781//NEDD8 activating enzyme activity;GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K10686//Ubiquitin mediated proteolysis
90390,0,0,0,0,3,0,38,0,49,0,0,0,MED30;mediator complex subunit 30,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016592//mediator complex,"GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0019827//stem cell maintenance;GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0046966//thyroid hormone receptor binding;GO:0005515//protein binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042809//vitamin D receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity,-
904,0,0,2,1,12,0,0,0,37,0,29,0,CCNT1;cyclin T1,GO:0005654//nucleoplasm;GO:0008024//positive transcription elongation factor complex b;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0010467//gene expression;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0051301//cell division;GO:0050434//positive regulation of viral transcription;GO:0007049//cell cycle;GO:0007179//transforming growth factor beta receptor signaling pathway",GO:0017069//snRNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0003677//DNA binding,K15188//Transcriptional misregulation in cancer
9040,0,51,0,11,34,0,27,9,50,0,21,0,UBE2M;ubiquitin-conjugating enzyme E2M,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,GO:0016567//protein ubiquitination;GO:0045116//protein neddylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006464//cellular protein modification process;GO:0043525//positive regulation of neuron apoptotic process,GO:0018169//ribosomal S6-glutamic acid ligase activity;GO:0005524//ATP binding;GO:0019788//NEDD8 ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K10579//Ubiquitin mediated proteolysis
90407,0,0,0,14,0,15,0,0,14,0,1,488,TMEM41A;transmembrane protein 41A,GO:0016021//integral component of membrane,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
90410,90,0,0,6,31,0,2,0,3,0,0,0,IFT20;intraflagellar transport 20,GO:0097546//ciliary base;GO:0036064//ciliary basal body;GO:0044292//dendrite terminus;GO:0070062//extracellular vesicular exosome;GO:0005794//Golgi apparatus;GO:0001750//photoreceptor outer segment;GO:0005813//centrosome;GO:0005929//cilium;GO:0005814//centriole;GO:0031514//motile cilium;GO:0030992//intraciliary transport particle B;GO:0032391//photoreceptor connecting cilium,GO:0055007//cardiac muscle cell differentiation;GO:0061351//neural precursor cell proliferation;GO:2000785//regulation of autophagic vacuole assembly;GO:0061512//protein localization to cilium;GO:0034067//protein localization to Golgi apparatus;GO:1902017//regulation of cilium assembly;GO:0042384//cilium assembly;GO:0007224//smoothened signaling pathway;GO:0008542//visual learning;GO:0051642//centrosome localization;GO:0001822//kidney development;GO:0035845//photoreceptor cell outer segment organization;GO:0042073//intraciliary transport;GO:0060828//regulation of canonical Wnt signaling pathway,GO:0002046//opsin binding;GO:0005515//protein binding,K00719//Metabolic pathways;Glycosphingolipid biosynthesis - globo series;K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
90411,2,53,55,60,82,0,11,2932,152,44,101,1,MCFD2;multiple coagulation factor deficiency 2,GO:0005794//Golgi apparatus;GO:0005783//endoplasmic reticulum;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0012507//ER to Golgi transport vesicle membrane,GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0015031//protein transport;GO:0016192//vesicle-mediated transport;GO:0043687//post-translational protein modification,GO:0005509//calcium ion binding,-
90416,0,0,0,5,31,24,16,0,8,0,10,0,C15orf57;chromosome 15 open reading frame 57,-,-,-,K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
90417,0,0,0,13,0,0,32,0,13,0,0,0,KNSTRN;kinetochore-localized astrin/SPAG5 binding protein,GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0072686//mitotic spindle,GO:0000070//mitotic sister chromatid segregation;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0007059//chromosome segregation;GO:0007051//spindle organization,GO:0005515//protein binding,-
90423,0,0,0,0,17,0,0,0,0,6,5,0,"ATP6V1E2;ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2",GO:0001669//acrosomal vesicle;GO:0005829//cytosol,GO:0051701//interaction with host;GO:0090382//phagosome maturation;GO:0033572//transferrin transport;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport,"GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism",K02150//Metabolic pathways;Oxidative phosphorylation;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Phagosome;Rheumatoid arthritis;Collecting duct acid secretion;Synaptic vesicle cycle
90427,0,0,0,6,40,0,2,0,74,0,7,0,BMF;Bcl2 modifying factor,GO:0005741//mitochondrial outer membrane;GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0001669//acrosomal vesicle;GO:0016459//myosin complex,GO:0006915//apoptotic process;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0097193//intrinsic apoptotic signaling pathway;GO:0043276//anoikis;GO:0090200//positive regulation of release of cytochrome c from mitochondria;GO:1900740//positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;GO:0032464//positive regulation of protein homooligomerization,GO:0005515//protein binding,-
9043,0,36,3,99,357,0,25,38,54,12,0,0,SPAG9;sperm associated antigen 9,GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol;GO:0016021//integral component of membrane;GO:0001669//acrosomal vesicle;GO:0048471//perinuclear region of cytoplasm;GO:0005737//cytoplasm,"GO:0042147//retrograde transport, endosome to Golgi;GO:0045666//positive regulation of neuron differentiation;GO:0042692//muscle cell differentiation;GO:0051149//positive regulation of muscle cell differentiation;GO:0051260//protein homooligomerization;GO:0007283//spermatogenesis;GO:0090074//negative regulation of protein homodimerization activity;GO:0051146//striated muscle cell differentiation;GO:0030335//positive regulation of cell migration;GO:0007257//activation of JUN kinase activity",GO:0048273//mitogen-activated protein kinase p38 binding;GO:0008432//JUN kinase binding;GO:0019894//kinesin binding;GO:0005515//protein binding,K04436//MAPK signaling pathway
9044,90,28,0,22,98,38,89,85,143,0,0,0,"BTAF1;BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa",GO:0005634//nucleus,"GO:0045892//negative regulation of transcription, DNA-templated;GO:0008152//metabolic process;GO:0035562//negative regulation of chromatin binding",GO:0004386//helicase activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005524//ATP binding,-
90441,0,0,0,0,13,0,24,1,32,0,0,0,ZNF622;zinc finger protein 622,GO:0005794//Golgi apparatus;GO:0005730//nucleolus;GO:0005737//cytoplasm,GO:0033674//positive regulation of kinase activity;GO:0046330//positive regulation of JNK cascade;GO:0043065//positive regulation of apoptotic process;GO:0043410//positive regulation of MAPK cascade;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
9045,0,71,0,37,182,0,0,0,11,0,0,0,RPL14;ribosomal protein L14,GO:0005829//cytosol;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,"GO:0016070//RNA metabolic process;GO:0019058//viral life cycle;GO:0006415//translational termination;GO:0016071//mRNA metabolic process;GO:0006414//translational elongation;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0042273//ribosomal large subunit biogenesis;GO:0006364//rRNA processing;GO:0016032//viral process;GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription",GO:0003723//RNA binding;GO:0003735//structural constituent of ribosome;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K02875//Ribosome
90459,0,0,0,0,0,20,26,0,31,0,0,1,ERI1;exoribonuclease 1,GO:0005730//nucleolus;GO:0071204//histone pre-mRNA 3'end processing complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0031047//gene silencing by RNA;GO:0031125//rRNA 3'-end processing;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0071044//histone mRNA catabolic process,GO:0046872//metal ion binding;GO:0008408//3'-5' exonuclease activity;GO:0043022//ribosome binding;GO:0071207//histone pre-mRNA stem-loop binding;GO:0019843//rRNA binding,-
9046,0,0,0,0,0,0,14,1,23,0,0,0,"DOK2;docking protein 2, 56kDa",GO:0005829//cytosol,GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0007265//Ras protein signal transduction;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway,GO:0005158//insulin receptor binding;GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0005057//receptor signaling protein activity,K14752//Measles
9047,0,0,0,0,0,10,0,0,5,0,0,0,SH2D2A;SH2 domain containing 2A,GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0008283//cell proliferation;GO:0007165//signal transduction;GO:0001525//angiogenesis;GO:0009967//positive regulation of signal transduction,GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0005070//SH3/SH2 adaptor activity,K08273//VEGF signaling pathway
9048,0,0,0,0,0,0,0,0,8,0,0,175,ARTN;artemin,GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0061146//Peyer's patch morphogenesis;GO:0007411//axon guidance;GO:0097021//lymphocyte migration into lymphoid organs;GO:0007405//neuroblast proliferation;GO:0050930//induction of positive chemotaxis;GO:0007422//peripheral nervous system development,GO:0008083//growth factor activity;GO:0005102//receptor binding,-
90480,97,0,0,0,7,0,8,0,15,0,0,0,"GADD45GIP1;growth arrest and DNA-damage-inducible, gamma interacting protein 1",GO:0005739//mitochondrion;GO:0005634//nucleus,GO:0016032//viral process;GO:0007049//cell cycle,GO:0005515//protein binding,-
90485,0,0,0,0,0,0,39,0,0,0,0,0,ZNF835;zinc finger protein 835,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
90488,0,0,1,64,169,0,0,0,18,0,0,0,TMEM263;transmembrane protein 263,GO:0016021//integral component of membrane,-,-,-
9049,64,1,0,11,0,0,0,0,2,0,0,0,AIP;aryl hydrocarbon receptor interacting protein,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051344//negative regulation of cyclic-nucleotide phosphodiesterase activity;GO:0010738//regulation of protein kinase A signaling;GO:0006626//protein targeting to mitochondrion;GO:0022417//protein maturation by protein folding;GO:2001141//regulation of RNA biosynthetic process;GO:0006805//xenobiotic metabolic process;GO:0007165//signal transduction,GO:0003713//transcription coactivator activity;GO:0005515//protein binding;GO:0036004//GAF domain binding;GO:0008134//transcription factor binding;GO:0051082//unfolded protein binding;GO:0004871//signal transducer activity,K06965//mRNA surveillance pathway
905,0,0,0,26,29,0,0,0,0,0,0,0,CCNT2;cyclin T2,GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0051301//cell division;GO:0016032//viral process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007049//cell cycle;GO:0006366//transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0010467//gene expression",GO:0019901//protein kinase binding,K15188//Transcriptional misregulation in cancer
9050,7,5,0,0,34,0,21,0,41,0,0,0,PSTPIP2;proline-serine-threonine phosphatase interacting protein 2,GO:0016020//membrane;GO:0005829//cytosol;GO:0005856//cytoskeleton,-,-,K12804//NOD-like receptor signaling pathway
90506,0,0,0,0,0,0,0,0,6,0,0,0,LRRC46;leucine rich repeat containing 46,-,-,-,-
90507,0,1,0,0,13,18,0,0,12,0,0,0,SCRN2;secernin 2,GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis,GO:0016805//dipeptidase activity,-
9051,83,0,0,0,0,0,61,0,72,0,14,0,PSTPIP1;proline-serine-threonine phosphatase interacting protein 1,GO:0005829//cytosol;GO:0001931//uropod;GO:0048471//perinuclear region of cytoplasm;GO:0001725//stress fiber;GO:0032154//cleavage furrow;GO:0016020//membrane;GO:0005826//actomyosin contractile ring;GO:0030027//lamellipodium,"GO:0007165//signal transduction;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0007155//cell adhesion;GO:0006954//inflammatory response;GO:0006897//endocytosis;GO:0045087//innate immune response",GO:0019903//protein phosphatase binding;GO:0003779//actin binding;GO:0005515//protein binding,K12804//NOD-like receptor signaling pathway
9052,0,0,0,0,0,0,0,0,20,0,0,0,"GPRC5A;G protein-coupled receptor, class C, group 5, member A",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0007165//signal transduction;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity,-
90522,0,78,0,7,73,0,0,0,25,251,43,0,YIF1B;Yip1 interacting factor homolog B (S. cerevisiae),GO:0016021//integral component of membrane,-,-,-
90523,0,0,0,0,0,30,36,2,8,0,0,0,MLIP;muscular LMNA-interacting protein,GO:0016605//PML body;GO:0031981//nuclear lumen;GO:0005635//nuclear envelope,-,-,-
90525,0,0,0,0,0,11,0,0,0,0,0,0,SHF;Src homology 2 domain containing F,-,GO:0006915//apoptotic process,-,K07365//T cell receptor signaling pathway;Axon guidance;Pathogenic Escherichia coli infection;ErbB signaling pathway;K04364//Focal adhesion;Dorso-ventral axis formation;Glioma;Neurotrophin signaling pathway;Hepatitis C;Non-small cell lung cancer;Endometrial cancer;Osteoclast differentiation;MAPK signaling pathway - fly;B cell receptor signaling pathway;Fc epsilon RI signaling pathway;Jak-STAT signaling pathway;Acute myeloid leukemia;Renal cell carcinoma;ErbB signaling pathway;Chronic myeloid leukemia;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Alcoholism;Prostate cancer;Insulin signaling pathway;Gap junction;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway
90527,93,1,0,0,0,92,0,18,13,0,27,0,DUOXA1;dual oxidase maturation factor 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0042743//hydrogen peroxide metabolic process;GO:0015031//protein transport;GO:0045666//positive regulation of neuron differentiation;GO:0050727//regulation of inflammatory response,-,-
90529,0,0,0,0,0,0,70,0,16,0,0,0,STPG1;sperm-tail PG-rich repeat containing 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process,-,-
9053,0,27,0,13,156,8,0,0,36,0,7,0,MAP7;microtubule-associated protein 7,GO:0016323//basolateral plasma membrane;GO:0005875//microtubule associated complex;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,GO:0007163//establishment or maintenance of cell polarity;GO:0035265//organ growth;GO:0006997//nucleus organization;GO:0072659//protein localization to plasma membrane;GO:0008283//cell proliferation;GO:0001578//microtubule bundle formation;GO:0033327//Leydig cell differentiation;GO:0060009//Sertoli cell development;GO:0007281//germ cell development;GO:0000226//microtubule cytoskeleton organization;GO:0048872//homeostasis of number of cells;GO:0009566//fertilization;GO:0006687//glycosphingolipid metabolic process;GO:0007283//spermatogenesis;GO:0000902//cell morphogenesis;GO:0006970//response to osmotic stress;GO:0032526//response to retinoic acid,GO:0005102//receptor binding;GO:0005198//structural molecule activity,-
9054,0,33,0,0,8,36,0,0,34,0,29,0,NFS1;NFS1 cysteine desulfurase,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005759//mitochondrial matrix;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006461//protein complex assembly;GO:0006534//cysteine metabolic process;GO:0000096//sulfur amino acid metabolic process;GO:0006766//vitamin metabolic process;GO:0006777//Mo-molybdopterin cofactor biosynthetic process;GO:0018283//iron incorporation into metallo-sulfur cluster,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0031071//cysteine desulfurase activity;GO:0030170//pyridoxal phosphate binding,"K04487//Metabolic pathways;Thiamine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Sulfur relay system;Biosynthesis of secondary metabolites"
9055,0,51,107,8,14,0,0,36,46,0,15,5,PRC1;protein regulator of cytokinesis 1,GO:0005730//nucleolus;GO:0000922//spindle pole;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005819//spindle;GO:0005737//cytoplasm,GO:0000910//cytokinesis;GO:0000022//mitotic spindle elongation,GO:0042802//identical protein binding;GO:0019901//protein kinase binding;GO:0008017//microtubule binding;GO:0005515//protein binding,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
90550,0,24,0,17,1,0,0,37,24,71,0,1,MCU;mitochondrial calcium uniporter,GO:0005743//mitochondrial inner membrane;GO:0031305//integral component of mitochondrial inner membrane;GO:0034704//calcium channel complex;GO:1990246//uniplex complex,GO:0032024//positive regulation of insulin secretion;GO:0051561//positive regulation of mitochondrial calcium ion concentration;GO:0019722//calcium-mediated signaling;GO:0006851//mitochondrial calcium ion transport;GO:0042593//glucose homeostasis;GO:0035786//protein complex oligomerization,GO:0005262//calcium channel activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0015292//uniporter activity,-
90557,0,0,46,0,0,23,22,0,2,0,0,0,CCDC74A;coiled-coil domain containing 74A,-,-,-,-
9056,0,0,0,0,36,0,19,0,0,48,0,0,"SLC7A7;solute carrier family 7 (amino acid transporter light chain, y+L system), member 7",GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0003333//amino acid transmembrane transport;GO:0006865//amino acid transport;GO:0006461//protein complex assembly;GO:0050900//leukocyte migration;GO:0007596//blood coagulation;GO:0006810//transport;GO:0006811//ion transport;GO:0055085//transmembrane transport;GO:0006520//cellular amino acid metabolic process,GO:0015171//amino acid transmembrane transporter activity,K13867//Protein digestion and absorption
9057,0,45,0,61,15,0,0,55,0,0,49,0,"SLC7A6;solute carrier family 7 (amino acid transporter light chain, y+L system), member 6",GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0050900//leukocyte migration;GO:0003333//amino acid transmembrane transport;GO:0006461//protein complex assembly;GO:0006865//amino acid transport;GO:0006520//cellular amino acid metabolic process;GO:0055085//transmembrane transport;GO:0006811//ion transport;GO:0007596//blood coagulation;GO:0006810//transport,GO:0015297//antiporter activity;GO:0015171//amino acid transmembrane transporter activity,-
90576,0,14,0,0,39,0,35,0,10,0,0,0,ZNF799;zinc finger protein 799,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9058,0,0,0,0,0,21,1,0,15,0,25,0,"SLC13A2;solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0006810//transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport;GO:0006835//dicarboxylic acid transport,GO:0015361//low-affinity sodium:dicarboxylate symporter activity,-
90580,0,1,0,0,0,15,5,107,13,0,0,0,C19orf52;chromosome 19 open reading frame 52,-,-,-,-
90586,56,0,0,0,6,0,0,1,14,0,0,0,"AOC4P;amine oxidase, copper containing 4, pseudogene",-,-,-,"K00276//Biosynthesis of secondary metabolites;Glycine, serine and threonine metabolism;Isoquinoline alkaloid biosynthesis;Phenylalanine metabolism;Tyrosine metabolism;Tropane, piperidine and pyridine alkaloid biosynthesis;beta-Alanine metabolism;Metabolic pathways"
90589,0,0,0,0,35,0,0,0,0,0,0,0,ZNF625;zinc finger protein 625,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
90592,0,0,0,0,20,0,3,0,0,0,0,0,ZNF700;zinc finger protein 700,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
90594,0,0,0,9,15,0,0,8,42,0,17,1,ZNF439;zinc finger protein 439,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9060,0,0,0,0,33,0,0,0,0,0,0,0,PAPSS2;3'-phosphoadenosine 5'-phosphosulfate synthase 2,GO:0005829//cytosol,GO:0005975//carbohydrate metabolic process;GO:0000103//sulfate assimilation;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0016310//phosphorylation;GO:0006805//xenobiotic metabolic process;GO:0044281//small molecule metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0007596//blood coagulation;GO:0001501//skeletal system development;GO:0060348//bone development,GO:0016779//nucleotidyltransferase activity;GO:0004781//sulfate adenylyltransferase (ATP) activity;GO:0004020//adenylylsulfate kinase activity;GO:0005524//ATP binding,K13811//Microbial metabolism in diverse environments;Metabolic pathways;Sulfur metabolism;Purine metabolism;Selenocompound metabolism
9061,0,53,2,38,140,2,2,0,0,0,0,0,PAPSS1;3'-phosphoadenosine 5'-phosphosulfate synthase 1,GO:0005829//cytosol,GO:0005975//carbohydrate metabolic process;GO:0000103//sulfate assimilation;GO:0050428//3'-phosphoadenosine 5'-phosphosulfate biosynthetic process;GO:0016310//phosphorylation;GO:0006805//xenobiotic metabolic process;GO:0050427//3'-phosphoadenosine 5'-phosphosulfate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0001501//skeletal system development,GO:0004781//sulfate adenylyltransferase (ATP) activity;GO:0016779//nucleotidyltransferase activity;GO:0005524//ATP binding;GO:0004020//adenylylsulfate kinase activity,K13811//Sulfur metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Selenocompound metabolism;Purine metabolism
90624,19,1,0,41,43,0,0,0,20,0,0,0,LYRM7;LYR motif containing 7,GO:0005759//mitochondrial matrix,-,-,K11447//Transcriptional misregulation in cancer
90627,0,0,0,1,1,17,0,0,25,0,0,0,STARD13;StAR-related lipid transfer (START) domain containing 13,GO:0005811//lipid particle;GO:0005829//cytosol;GO:0031966//mitochondrial membrane,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0008289//lipid binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding,K08773//Pancreatic cancer;Pathways in cancer;K05732//Leukocyte transendothelial migration;Focal adhesion;Regulation of actin cytoskeleton;K07526//Axon guidance
9063,42,0,0,19,111,40,0,50,74,0,0,19,"PIAS2;protein inhibitor of activated STAT, 2",GO:0016605//PML body;GO:0016607//nuclear speck;GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0016925//protein sumoylation;GO:0060766//negative regulation of androgen receptor signaling pathway;GO:0045667//regulation of osteoblast differentiation",GO:0050681//androgen receptor binding;GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding;GO:0019789//SUMO ligase activity;GO:0003713//transcription coactivator activity,K16063//Small cell lung cancer;Ubiquitin mediated proteolysis;Jak-STAT signaling pathway;Pathways in cancer
90634,0,0,0,0,1,0,47,0,23,0,4,0,N4BP2L1;NEDD4 binding protein 2-like 1,-,-,-,-
90637,0,0,0,0,0,0,0,0,21,0,1,0,"ZFAND2A;zinc finger, AN1-type domain 2A",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000502//proteasome complex,GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0071243//cellular response to arsenic-containing substance,GO:0008270//zinc ion binding,-
90639,0,0,0,4,11,0,37,0,0,0,0,0,COX19;cytochrome c oxidase assembly homolog 19 (S. cerevisiae),GO:0005737//cytoplasm;GO:0005829//cytosol,-,-,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01598//Metabolic pathways;Pantothenate and CoA biosynthesis
9064,137,2,0,0,11,41,20,108,19,0,1,0,MAP3K6;mitogen-activated protein kinase kinase kinase 6,-,GO:0000186//activation of MAPKK activity;GO:0007257//activation of JUN kinase activity;GO:0006468//protein phosphorylation;GO:0007165//signal transduction,GO:0000287//magnesium ion binding;GO:0004709//MAP kinase kinase kinase activity;GO:0005524//ATP binding,K04425//MAPK signaling pathway
90649,0,0,46,0,0,0,18,0,10,0,0,0,ZNF486;zinc finger protein 486,GO:0005634//nucleus;GO:0070062//extracellular vesicular exosome,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
90665,0,0,0,19,10,0,0,0,0,0,21,0,"TBL1Y;transducin (beta)-like 1, Y-linked",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,K04508//Wnt signaling pathway
90668,2,0,0,0,26,24,1,19,97,88,12,294,LRRC16B;leucine rich repeat containing 16B,GO:0005737//cytoplasm,-,-,K11147//Metabolic pathways;Peroxisome;Retinol metabolism
90673,0,0,0,0,10,0,8,0,13,0,0,0,"PPP1R3E;protein phosphatase 1, regulatory subunit 3E",-,GO:0005977//glycogen metabolic process,-,K07189//Insulin signaling pathway
90678,0,0,0,1,0,2,0,2,12,51,1,0,LRSAM1;leucine rich repeat and sterile alpha motif containing 1,GO:0005576//extracellular region;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0000209//protein polyubiquitination;GO:0051865//protein autoubiquitination;GO:0008219//cell death;GO:0045806//negative regulation of endocytosis;GO:0070086//ubiquitin-dependent endocytosis;GO:0030163//protein catabolic process;GO:0046755//viral budding,GO:0008270//zinc ion binding;GO:0005179//hormone activity;GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,-
9069,0,0,0,0,18,0,0,0,15,0,0,0,CLDN12;claudin 12,GO:0016021//integral component of membrane;GO:0005923//tight junction;GO:0016328//lateral plasma membrane,GO:0034329//cell junction assembly;GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0070830//tight junction assembly,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
90693,95,0,0,0,0,0,0,36,28,0,0,0,CCDC126;coiled-coil domain containing 126,GO:0005576//extracellular region;GO:0016020//membrane,GO:0006487//protein N-linked glycosylation,"GO:0030144//alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity",K00744//Metabolic pathways;N-Glycan biosynthesis
9070,0,12,0,10,15,0,9,0,32,0,7,0,"ASH2L;ash2 (absent, small, or homeotic)-like (Drosophila)",GO:0048188//Set1C/COMPASS complex;GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,"GO:0006974//cellular response to DNA damage stimulus;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0008284//positive regulation of cell proliferation;GO:0006355//regulation of transcription, DNA-templated;GO:0030097//hemopoiesis;GO:0051568//histone H3-K4 methylation;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0043627//response to estrogen",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0044212//transcription regulatory region DNA binding,-
90701,12,33,0,8,52,0,0,0,18,0,0,0,SEC11C;SEC11 homolog C (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006508//proteolysis;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0006465//signal peptide processing;GO:0050796//regulation of insulin secretion,GO:0008236//serine-type peptidase activity,K13280//Protein export
9071,0,0,0,0,0,34,0,0,12,0,0,0,CLDN10;claudin 10,GO:0016021//integral component of membrane;GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0007155//cell adhesion;GO:0006811//ion transport,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Tight junction;Cell adhesion molecules (CAMs);Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
9073,0,0,0,7,8,0,7,0,67,0,0,0,CLDN8;claudin 8,GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0005783//endoplasmic reticulum;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Tight junction;Cell adhesion molecules (CAMs);Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
90736,99,0,0,0,7,0,0,0,15,0,0,0,"FAM104B;family with sequence similarity 104, member B",-,-,-,-
90737,0,0,0,0,0,11,0,0,13,0,2,0,"PAGE5;P antigen family, member 5 (prostate associated)",-,-,-,-
9074,0,0,0,0,0,0,0,0,9,0,0,0,CLDN6;claudin 6,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0005923//tight junction,GO:0016032//viral process;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0045216//cell-cell junction organization,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Hepatitis C;Tight junction;Cell adhesion molecules (CAMs);Leukocyte transendothelial migration;Pathogenic Escherichia coli infection
9075,0,0,0,0,0,21,0,0,0,1,4,0,CLDN2;claudin 2,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0016021//integral component of membrane,GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules,GO:0005198//structural molecule activity;GO:0042802//identical protein binding,K06087//Leukocyte transendothelial migration;Pathogenic Escherichia coli infection;Hepatitis C;Tight junction;Cell adhesion molecules (CAMs)
9076,0,0,0,0,0,1,0,0,9,0,0,0,CLDN1;claudin 1,GO:0005887//integral component of plasma membrane;GO:0016328//lateral plasma membrane;GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane;GO:0005923//tight junction,GO:0061436//establishment of skin barrier;GO:0045216//cell-cell junction organization;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0007155//cell adhesion;GO:0016032//viral process,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Tight junction;Cell adhesion molecules (CAMs);Hepatitis C;Pathogenic Escherichia coli infection;Leukocyte transendothelial migration
90768,0,0,0,0,0,1,0,0,2,0,0,0,MGC45800;uncharacterized LOC90768,-,-,-,-
9077,0,0,0,0,0,0,0,0,27,0,0,0,"DIRAS3;DIRAS family, GTP-binding RAS-like 3",GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0006349//regulation of gene expression by genetic imprinting;GO:0006184//GTP catabolic process,GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
90780,0,0,2,6,66,0,0,45,60,0,34,0,PYGO2;pygopus family PHD finger 2,GO:0005634//nucleus,GO:0035065//regulation of histone acetylation;GO:0033599//regulation of mammary gland epithelial cell proliferation;GO:0001822//kidney development;GO:0009791//post-embryonic development;GO:0048589//developmental growth;GO:0002088//lens development in camera-type eye;GO:0001701//in utero embryonic development;GO:0051569//regulation of histone H3-K4 methylation;GO:0035563//positive regulation of chromatin binding;GO:0060021//palate development;GO:0030879//mammary gland development;GO:0007420//brain development;GO:0060070//canonical Wnt signaling pathway;GO:0007289//spermatid nucleus differentiation,GO:0003682//chromatin binding;GO:0005515//protein binding;GO:0035034//histone acetyltransferase regulator activity;GO:0042393//histone binding;GO:0008270//zinc ion binding,-
9079,0,0,0,0,0,9,0,0,0,0,0,1,LDB2;LIM domain binding 2,GO:0005667//transcription factor complex;GO:0005634//nucleus,GO:0035019//somatic stem cell maintenance;GO:0001942//hair follicle development;GO:0010669//epithelial structure maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044089//positive regulation of cellular component biogenesis,GO:0030274//LIM domain binding;GO:0019899//enzyme binding;GO:0003712//transcription cofactor activity,K15617//Transcriptional misregulation in cancer
90799,0,0,23,17,27,0,0,0,14,0,5,0,CEP95;centrosomal protein 95kDa,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000922//spindle pole,-,-,K05702//Tight junction;Leukocyte transendothelial migration;Adherens junction;K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
908,0,41,0,1,17,0,0,0,18,0,0,0,"CCT6A;chaperonin containing TCP1, subunit 6A (zeta 1)",GO:0002199//zona pellucida receptor complex;GO:0005829//cytosol;GO:0001669//acrosomal vesicle;GO:0005874//microtubule;GO:0070062//extracellular vesicular exosome;GO:0005832//chaperonin-containing T-complex;GO:0044297//cell body;GO:0005737//cytoplasm,GO:0006457//protein folding;GO:0051084//'de novo' posttranslational protein folding;GO:0007339//binding of sperm to zona pellucida;GO:0044267//cellular protein metabolic process,GO:0044822//poly(A) RNA binding;GO:0051082//unfolded protein binding;GO:0005524//ATP binding,-
9080,0,0,0,0,0,0,0,0,8,0,10,0,CLDN9;claudin 9,GO:0016021//integral component of membrane;GO:0005923//tight junction;GO:0005886//plasma membrane,GO:0045216//cell-cell junction organization;GO:0034329//cell junction assembly;GO:0070830//tight junction assembly;GO:0016338//calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;GO:0016032//viral process,GO:0042802//identical protein binding;GO:0005198//structural molecule activity,K06087//Pathogenic Escherichia coli infection;Leukocyte transendothelial migration;Cell adhesion molecules (CAMs);Tight junction;Hepatitis C
90806,0,0,1,0,41,0,0,0,0,0,0,0,ANGEL2;angel homolog 2 (Drosophila),-,-,-,K12603//RNA degradation
90809,0,1,0,0,17,0,0,0,10,0,0,0,TMEM55B;transmembrane protein 55B,GO:0031902//late endosome membrane;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
90826,0,0,0,13,25,0,0,0,43,0,0,0,PRMT9;protein arginine methyltransferase 9,GO:0005737//cytoplasm,GO:0006479//protein methylation,GO:0008276//protein methyltransferase activity,-
90827,0,0,0,0,0,0,17,0,45,0,0,0,ZNF479;zinc finger protein 479,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
90835,0,0,7,0,23,0,0,0,23,4,9,0,C16orf93;chromosome 16 open reading frame 93,-,-,-,-
90843,0,38,3,59,108,1,0,0,4,0,0,0,TCEAL8;transcription elongation factor A (SII)-like 8,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",-,-
90850,0,27,0,0,0,0,0,0,26,0,0,0,ZNF598;zinc finger protein 598,-,-,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding,-
90853,0,0,0,0,0,0,0,18,28,0,0,0,SPOCD1;SPOC domain containing 1,-,"GO:0010923//negative regulation of phosphatase activity;GO:0006351//transcription, DNA-templated",-,-
9086,0,0,0,8,22,0,0,0,0,0,0,0,"EIF1AY;eukaryotic translation initiation factor 1A, Y-linked",-,GO:0006413//translational initiation,GO:0005515//protein binding;GO:0003743//translation initiation factor activity,K03236//RNA transport
90861,47,85,2,97,465,0,5,43,20,0,0,0,HN1L;hematological and neurological expressed 1-like,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane,-,-,-
90864,0,2,1,2,12,0,0,12,0,0,49,0,SPSB3;splA/ryanodine receptor domain and SOCS box containing 3,-,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,-,-
90865,69,0,0,0,0,17,46,14,14,0,0,0,IL33;interleukin 33,GO:0005634//nucleus;GO:0030133//transport vesicle;GO:0005694//chromosome;GO:0005615//extracellular space,"GO:0032753//positive regulation of interleukin-4 production;GO:0032736//positive regulation of interleukin-13 production;GO:0032689//negative regulation of interferon-gamma production;GO:0043032//positive regulation of macrophage activation;GO:0002826//negative regulation of T-helper 1 type immune response;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0032754//positive regulation of interleukin-5 production;GO:0006351//transcription, DNA-templated;GO:0051024//positive regulation of immunoglobulin secretion;GO:0051025//negative regulation of immunoglobulin secretion;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0090197//positive regulation of chemokine secretion;GO:0002686//negative regulation of leukocyte migration;GO:0050729//positive regulation of inflammatory response;GO:0097191//extrinsic apoptotic signaling pathway;GO:0002830//positive regulation of type 2 immune response",GO:0005125//cytokine activity;GO:0005515//protein binding,K12967//Cytosolic DNA-sensing pathway;Influenza A
9087,0,0,0,7,0,0,0,0,0,0,0,0,"TMSB4Y;thymosin beta 4, Y-linked",GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005829//cytosol,GO:0030036//actin cytoskeleton organization;GO:0008064//regulation of actin polymerization or depolymerization;GO:0030334//regulation of cell migration;GO:0042989//sequestering of actin monomers,GO:0003779//actin binding,K05764//Regulation of actin cytoskeleton
90871,0,29,0,0,7,0,23,72,0,0,0,0,TMEM261;transmembrane protein 261,GO:0016021//integral component of membrane,-,-,-
90874,0,21,1,5,22,0,1,0,13,0,0,0,ZNF697;zinc finger protein 697,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
9088,0,32,46,23,37,0,0,0,22,0,108,152,"PKMYT1;protein kinase, membrane associated tyrosine/threonine 1",GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0005654//nucleoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0006468//protein phosphorylation;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007088//regulation of mitosis;GO:0007067//mitotic nuclear division;GO:0010923//negative regulation of phosphatase activity;GO:0000082//G1/S transition of mitotic cell cycle,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0016301//kinase activity;GO:0005524//ATP binding,K06633//Progesterone-mediated oocyte maturation;Cell cycle;Oocyte meiosis
909,1,0,0,0,0,19,57,0,0,0,0,574,CD1A;CD1a molecule,GO:0010008//endosome membrane;GO:0005887//integral component of plasma membrane,GO:0006955//immune response;GO:0019882//antigen processing and presentation,GO:0005515//protein binding,K06448//Amoebiasis;Hematopoietic cell lineage
9091,0,0,0,0,0,9,0,53,45,0,0,0,"PIGQ;phosphatidylinositol glycan anchor biosynthesis, class Q",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000506//glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0005975//carbohydrate metabolic process;GO:0016254//preassembly of GPI anchor in ER membrane,GO:0017176//phosphatidylinositol N-acetylglucosaminyltransferase activity,K03860//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
9092,124,0,0,0,10,12,0,53,52,7,28,0,SART1;squamous cell carcinoma antigen recognized by T cells,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005634//nucleus;GO:0071013//catalytic step 2 spliceosome;GO:0005794//Golgi apparatus;GO:0005654//nucleoplasm;GO:0005737//cytoplasm,"GO:0045585//positive regulation of cytotoxic T cell differentiation;GO:0007050//cell cycle arrest;GO:0097193//intrinsic apoptotic signaling pathway;GO:0000398//mRNA splicing, via spliceosome;GO:0000387//spliceosomal snRNP assembly",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K11984//Spliceosome
9093,0,0,0,0,2,0,0,0,0,0,0,0,"DNAJA3;DnaJ (Hsp40) homolog, subfamily A, member 3",GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm;GO:0030054//cell junction;GO:0031594//neuromuscular junction;GO:0033256//I-kappaB/NF-kappaB complex;GO:0045211//postsynaptic membrane;GO:0005634//nucleus;GO:0019897//extrinsic component of plasma membrane;GO:0008385//IkappaB kinase complex;GO:0005884//actin filament;GO:0042645//mitochondrial nucleoid;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0005739//mitochondrion,GO:0009408//response to heat;GO:0006457//protein folding;GO:0008285//negative regulation of cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0050821//protein stabilization;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043069//negative regulation of programmed cell death;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0007264//small GTPase mediated signal transduction;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0007528//neuromuscular junction development;GO:0006469//negative regulation of protein kinase activity;GO:0006924//activation-induced cell death of T cells;GO:0007569//cell aging;GO:0060336//negative regulation of interferon-gamma-mediated signaling pathway;GO:0034341//response to interferon-gamma;GO:0033077//T cell differentiation in thymus;GO:0043065//positive regulation of apoptotic process;GO:0042102//positive regulation of T cell proliferation;GO:0071340//skeletal muscle acetylcholine-gated channel clustering;GO:0006264//mitochondrial DNA replication;GO:0050790//regulation of catalytic activity;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0031398//positive regulation of protein ubiquitination,GO:0005083//small GTPase regulator activity;GO:0005133//interferon-gamma receptor binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0051082//unfolded protein binding;GO:0008134//transcription factor binding;GO:0030971//receptor tyrosine kinase binding;GO:0005524//ATP binding;GO:0051059//NF-kappaB binding;GO:0019901//protein kinase binding;GO:0030544//Hsp70 protein binding,-
90933,81,33,0,32,46,0,0,0,0,0,1,1,TRIM41;tripartite motif containing 41,GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
9094,0,42,0,0,0,5,0,27,35,0,0,0,UNC119;unc-119 homolog (C. elegans),GO:0005829//cytosol;GO:0051233//spindle midzone;GO:0045171//intercellular bridge;GO:0000922//spindle pole;GO:0005813//centrosome,"GO:2001287//negative regulation of caveolin-mediated endocytosis;GO:0007268//synaptic transmission;GO:1900186//negative regulation of clathrin-mediated endocytosis;GO:0007109//cytokinesis, completion of separation;GO:0007602//phototransduction;GO:0007601//visual perception;GO:0042953//lipoprotein transport;GO:0061098//positive regulation of protein tyrosine kinase activity",GO:0008289//lipid binding;GO:0005515//protein binding,K13758//Purine metabolism
9095,0,0,0,0,0,0,0,0,8,0,0,428,TBX19;T-box 19,GO:0005634//nucleus,"GO:0045165//cell fate commitment;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0042127//regulation of cell proliferation;GO:0021983//pituitary gland development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009653//anatomical structure morphogenesis;GO:0006351//transcription, DNA-templated;GO:0045595//regulation of cell differentiation",GO:0001158//enhancer sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
90952,0,0,0,0,0,26,22,0,7,0,0,63,ESAM;endothelial cell adhesion molecule,GO:0005923//tight junction;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005912//adherens junction,GO:0007596//blood coagulation;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0050900//leukocyte migration;GO:0016337//single organismal cell-cell adhesion,-,K06787//Leukocyte transendothelial migration;Cell adhesion molecules (CAMs)
90956,0,0,50,0,6,0,0,0,12,256,0,432,ADCK2;aarF domain containing kinase 2,GO:0016021//integral component of membrane;GO:0005739//mitochondrion,GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
90957,0,43,0,20,36,22,9,0,39,0,0,0,DHX57;DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57,-,GO:0006200//ATP catabolic process,GO:0008026//ATP-dependent helicase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005524//ATP binding,-
9096,20,0,0,0,0,12,0,0,37,0,0,233,TBX18;T-box 18,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0050679//positive regulation of epithelial cell proliferation;GO:0022409//positive regulation of cell-cell adhesion;GO:0016331//morphogenesis of embryonic epithelium;GO:0006351//transcription, DNA-templated;GO:0003163//sinoatrial node development;GO:0051145//smooth muscle cell differentiation;GO:2000729//positive regulation of mesenchymal cell proliferation involved in ureter development;GO:0090103//cochlea morphogenesis;GO:0001756//somitogenesis;GO:0009948//anterior/posterior axis specification;GO:0007605//sensory perception of sound;GO:0072189//ureter development;GO:0060829//negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0042803//protein homodimerization activity;GO:0000976//transcription regulatory region sequence-specific DNA binding;GO:0001106//RNA polymerase II transcription corepressor activity,-
9097,0,76,1,95,117,14,0,122,0,0,19,0,USP14;ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase),GO:0005737//cytoplasm;GO:0000502//proteasome complex;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0045202//synapse;GO:0009986//cell surface;GO:0016023//cytoplasmic membrane-bounded vesicle,GO:0061136//regulation of proteasomal protein catabolic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0010951//negative regulation of endopeptidase activity;GO:0050920//regulation of chemotaxis;GO:0016579//protein deubiquitination;GO:0007268//synaptic transmission,GO:0070628//proteasome binding;GO:0004221//ubiquitin thiolesterase activity;GO:0004866//endopeptidase inhibitor activity;GO:0008193//tRNA guanylyltransferase activity;GO:0004843//ubiquitin-specific protease activity;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity,-
9098,85,0,0,12,52,58,13,2,52,0,9,1,USP6;ubiquitin specific peptidase 6,GO:0005886//plasma membrane;GO:0005764//lysosome;GO:0055037//recycling endosome;GO:0005737//cytoplasm,GO:0016579//protein deubiquitination;GO:0032851//positive regulation of Rab GTPase activity;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0060627//regulation of vesicle-mediated transport;GO:0006464//cellular protein modification process,GO:0005516//calmodulin binding;GO:0005097//Rab GTPase activator activity;GO:0003676//nucleic acid binding;GO:0005515//protein binding;GO:0004197//cysteine-type endopeptidase activity;GO:0004843//ubiquitin-specific protease activity,-
90987,0,20,0,0,0,0,0,0,3,13,8,0,ZNF251;zinc finger protein 251,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
9099,100,0,0,0,4,22,0,5,15,74,12,2,USP2;ubiquitin specific peptidase 2,GO:0005813//centrosome;GO:0005938//cell cortex;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0007517//muscle organ development;GO:0050821//protein stabilization;GO:0048642//negative regulation of skeletal muscle tissue development;GO:0045931//positive regulation of mitotic cell cycle;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0007049//cell cycle;GO:0016579//protein deubiquitination;GO:0048643//positive regulation of skeletal muscle tissue development,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004843//ubiquitin-specific protease activity;GO:0004221//ubiquitin thiolesterase activity;GO:0004197//cysteine-type endopeptidase activity;GO:0042802//identical protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0030332//cyclin binding,-
90990,0,0,0,0,22,0,29,0,45,7,0,0,KIFC2;kinesin family member C2,GO:0005737//cytoplasm;GO:0005874//microtubule;GO:0005871//kinesin complex,GO:0007018//microtubule-based movement;GO:0008152//metabolic process;GO:0006200//ATP catabolic process,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity,-
90993,0,0,0,0,0,0,0,1,11,0,0,0,CREB3L1;cAMP responsive element binding protein 3-like 1,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,"GO:0030500//regulation of bone mineralization;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006986//response to unfolded protein",GO:0043565//sequence-specific DNA binding;GO:0003682//chromatin binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K09048//Vasopressin-regulated water reabsorption;Amphetamine addiction;Melanogenesis;Cholinergic synapse;Huntington's disease;Cocaine addiction;Dopaminergic synapse;Alcoholism;Prostate cancer
91,0,0,0,20,0,0,0,0,53,0,8,0,"ACVR1B;activin A receptor, type IB",GO:0005887//integral component of plasma membrane;GO:0009986//cell surface;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,"GO:0045648//positive regulation of erythrocyte differentiation;GO:0038092//nodal signaling pathway;GO:0030308//negative regulation of cell growth;GO:0007417//central nervous system development;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0001942//hair follicle development;GO:1901165//positive regulation of trophoblast cell migration;GO:0001701//in utero embryonic development;GO:0006355//regulation of transcription, DNA-templated;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0032924//activin receptor signaling pathway;GO:0046545//development of primary female sexual characteristics;GO:0097191//extrinsic apoptotic signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0000082//G1/S transition of mitotic cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0046777//protein autophosphorylation;GO:0023014//signal transduction by phosphorylation;GO:0007165//signal transduction","GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0019838//growth factor binding;GO:0031625//ubiquitin protein ligase binding;GO:0046332//SMAD binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0016361//activin receptor activity, type I;GO:0005524//ATP binding;GO:0034711//inhibin binding",K13567//Cytokine-cytokine receptor interaction
910,8,0,0,0,0,27,0,0,0,0,0,0,CD1B;CD1b molecule,GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0019882//antigen processing and presentation;GO:0006955//immune response,GO:0005515//protein binding,K06448//Hematopoietic cell lineage;Amoebiasis
9100,4,56,0,33,129,39,18,0,35,2,0,0,USP10;ubiquitin specific peptidase 10,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005769//early endosome;GO:0045111//intermediate filament cytoskeleton,"GO:0016579//protein deubiquitination;GO:0030330//DNA damage response, signal transduction by p53 class mediator;GO:0006281//DNA repair;GO:0010506//regulation of autophagy;GO:0006914//autophagy;GO:0006511//ubiquitin-dependent protein catabolic process",GO:0044822//poly(A) RNA binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0044325//ion channel binding;GO:0004843//ubiquitin-specific protease activity;GO:0002039//p53 binding;GO:0004221//ubiquitin thiolesterase activity,-
9101,0,20,0,11,117,38,35,0,63,0,4,0,USP8;ubiquitin specific peptidase 8,GO:0030496//midbody;GO:0001669//acrosomal vesicle;GO:0005829//cytosol;GO:0019897//extrinsic component of plasma membrane;GO:0005634//nucleus;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0005737//cytoplasm,GO:0071108//protein K48-linked deubiquitination;GO:0008283//cell proliferation;GO:0070536//protein K63-linked deubiquitination;GO:0007032//endosome organization;GO:0016579//protein deubiquitination;GO:0007265//Ras protein signal transduction;GO:0000281//mitotic cytokinesis;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0017124//SH3 domain binding;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0004843//ubiquitin-specific protease activity,K11839//Endocytosis
91010,2,120,71,75,207,29,0,456,191,265,276,434,FMNL3;formin-like 3,GO:0005737//cytoplasm,GO:0008360//regulation of cell shape;GO:0007010//cytoskeleton organization;GO:0016477//cell migration;GO:0030036//actin cytoskeleton organization,GO:0032794//GTPase activating protein binding;GO:0003779//actin binding;GO:0017048//Rho GTPase binding,K04512//Wnt signaling pathway
91012,94,15,0,9,0,0,8,0,21,0,0,62,CERS5;ceramide synthase 5,GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0044281//small molecule metabolic process;GO:0030148//sphingolipid biosynthetic process;GO:0046513//ceramide biosynthetic process;GO:0006665//sphingolipid metabolic process,GO:0050291//sphingosine N-acyltransferase activity;GO:0003677//DNA binding,K04710//Metabolic pathways;Sphingolipid metabolism
9103,0,0,0,0,0,11,16,0,11,0,0,0,"FCGR2C;Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0006955//immune response;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity;GO:0019864//IgG binding;GO:0005515//protein binding,K06472//Staphylococcus aureus infection;Phagosome;Leishmaniasis;Systemic lupus erythematosus;Osteoclast differentiation;Fc gamma R-mediated phagocytosis;Tuberculosis
91039,0,0,0,0,18,3,0,0,65,47,16,0,DPP9;dipeptidyl-peptidase 9,GO:0005829//cytosol;GO:0016020//membrane;GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0004177//aminopeptidase activity;GO:0042802//identical protein binding;GO:0008236//serine-type peptidase activity,-
9104,0,0,0,0,16,15,46,0,6,0,8,0,RGN;regucalcin,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0032781//positive regulation of ATPase activity;GO:0019853//L-ascorbic acid biosynthetic process;GO:0006874//cellular calcium ion homeostasis;GO:0050848//regulation of calcium-mediated signaling,GO:0008270//zinc ion binding;GO:0005509//calcium ion binding;GO:0004341//gluconolactonase activity;GO:0030234//enzyme regulator activity,K01053//Caprolactam degradation;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Pentose phosphate pathway;Metabolic pathways;Ascorbate and aldarate metabolism
91050,0,33,0,14,9,0,0,58,9,0,1,343,CCDC149;coiled-coil domain containing 149,-,-,-,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);K12478//Tuberculosis;Phagosome;Endocytosis
91056,0,0,0,0,6,0,4,0,22,0,0,0,"AP5B1;adaptor-related protein complex 5, beta 1 subunit",GO:0030119//AP-type membrane coat adaptor complex;GO:0005765//lysosomal membrane,GO:0015031//protein transport;GO:0016197//endosomal transport,GO:0005515//protein binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
91057,54,0,0,0,7,0,0,0,22,0,0,0,CCDC34;coiled-coil domain containing 34,-,-,-,-
9107,8,0,0,24,57,0,0,0,42,72,0,0,MTMR6;myotubularin related protein 6,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005635//nuclear envelope,GO:0044281//small molecule metabolic process;GO:0071805//potassium ion transmembrane transport;GO:0006661//phosphatidylinositol biosynthetic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006644//phospholipid metabolic process;GO:0006470//protein dephosphorylation,GO:0015269//calcium-activated potassium channel activity;GO:0004725//protein tyrosine phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity,K01112//Fructose and mannose metabolism
91074,0,0,1,0,0,33,1,0,21,223,8,0,ANKRD30A;ankyrin repeat domain 30A,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Gastric acid secretion;Calcium signaling pathway
9108,0,1,1,140,267,0,0,7,25,0,22,0,MTMR7;myotubularin related protein 7,GO:0005829//cytosol;GO:0016020//membrane,GO:0046856//phosphatidylinositol dephosphorylation;GO:0006661//phosphatidylinositol biosynthetic process;GO:0046855//inositol phosphate dephosphorylation;GO:0044281//small molecule metabolic process;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0006644//phospholipid metabolic process,GO:0004725//protein tyrosine phosphatase activity,K01112//Fructose and mannose metabolism
911,0,0,0,0,0,1,27,0,23,0,0,0,CD1C;CD1c molecule,GO:0005887//integral component of plasma membrane;GO:0010008//endosome membrane;GO:0005886//plasma membrane,GO:0019882//antigen processing and presentation;GO:0002286//T cell activation involved in immune response,GO:0071723//lipopeptide binding;GO:0030884//exogenous lipid antigen binding;GO:0051861//glycolipid binding;GO:0030883//endogenous lipid antigen binding,K06448//Amoebiasis;Hematopoietic cell lineage
9110,0,46,0,22,155,29,0,0,51,0,0,0,MTMR4;myotubularin related protein 4,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0031901//early endosome membrane,GO:0006644//phospholipid metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0006661//phosphatidylinositol biosynthetic process,GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004725//protein tyrosine phosphatase activity,-
91107,0,23,0,0,19,21,21,66,48,4,14,0,TRIM47;tripartite motif containing 47,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0008270//zinc ion binding,-
9111,0,0,0,0,0,0,0,18,0,0,0,0,NMI;N-myc (and STAT) interactor,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:2001141//regulation of RNA biosynthetic process;GO:0007259//JAK-STAT cascade;GO:0006954//inflammatory response;GO:0006366//transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0003712//transcription cofactor activity,-
9112,0,0,0,0,11,0,22,72,59,0,9,0,MTA1;metastasis associated 1,GO:0005737//cytoplasm;GO:0005783//endoplasmic reticulum;GO:0016581//NuRD complex;GO:0005635//nuclear envelope;GO:0005634//nucleus;GO:0005874//microtubule;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,"GO:0032922//circadian regulation of gene expression;GO:0050727//regulation of inflammatory response;GO:0032496//response to lipopolysaccharide;GO:0040029//regulation of gene expression, epigenetic;GO:0043153//entrainment of circadian clock by photoperiod;GO:0033363//secretory granule organization;GO:0045475//locomotor rhythm;GO:0006302//double-strand break repair;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0007165//signal transduction;GO:0006355//regulation of transcription, DNA-templated;GO:0010212//response to ionizing radiation",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0001047//core promoter binding;GO:0019899//enzyme binding;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0001046//core promoter sequence-specific DNA binding,-
91120,12,0,0,8,0,0,37,0,21,0,5,0,ZNF682;zinc finger protein 682,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9113,0,73,2,34,301,17,0,186,45,0,74,0,LATS1;large tumor suppressor kinase 1,GO:0005829//cytosol;GO:0005815//microtubule organizing center;GO:0000922//spindle pole,GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0043254//regulation of protein complex assembly;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0030216//keratinocyte differentiation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0006468//protein phosphorylation;GO:0035329//hippo signaling;GO:0000819//sister chromatid segregation;GO:0030833//regulation of actin filament polymerization;GO:0051220//cytoplasmic sequestering of protein;GO:0007067//mitotic nuclear division;GO:0009755//hormone-mediated signaling pathway,GO:0004674//protein serine/threonine kinase activity;GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0000287//magnesium ion binding,-
91133,0,0,0,0,0,0,0,0,20,0,4,0,L3MBTL4;l(3)mbt-like 4 (Drosophila),GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0016568//chromatin modification;GO:0006351//transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
91137,1,1,0,26,201,2,0,103,13,0,0,0,"SLC25A46;solute carrier family 25, member 46",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0006810//transport,-,-
9114,0,0,0,0,2,0,0,0,46,0,0,0,"ATP6V0D1;ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1","GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0030670//phagocytic vesicle membrane;GO:0016020//membrane;GO:0008021//synaptic vesicle;GO:0010008//endosome membrane;GO:0043679//axon terminus;GO:0016324//apical plasma membrane;GO:0005813//centrosome;GO:0005765//lysosomal membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0033179//proton-transporting V-type ATPase, V0 domain",GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0015992//proton transport;GO:0042384//cilium assembly;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport;GO:0044267//cellular protein metabolic process;GO:0007420//brain development;GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0030968//endoplasmic reticulum unfolded protein response,"GO:0008553//hydrogen-exporting ATPase activity, phosphorylative mechanism;GO:0032403//protein complex binding;GO:0005515//protein binding",K02146//Metabolic pathways;Oxidative phosphorylation;Epithelial cell signaling in Helicobacter pylori infection;Lysosome;Vibrio cholerae infection;Phagosome;Collecting duct acid secretion;Rheumatoid arthritis;Synaptic vesicle cycle;Tuberculosis
91147,0,0,0,0,11,23,0,46,15,0,9,0,TMEM67;transmembrane protein 67,GO:0005813//centrosome;GO:0036038//TCTN-B9D complex;GO:0005789//endoplasmic reticulum membrane;GO:0060170//ciliary membrane;GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane,GO:0060271//cilium morphogenesis;GO:0010826//negative regulation of centrosome duplication;GO:0042384//cilium assembly;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process,GO:0031005//filamin binding;GO:0051082//unfolded protein binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
91151,0,0,1,16,79,0,0,0,7,0,0,0,TIGD7;tigger transposable element derived 7,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
91156,0,0,0,0,0,33,0,0,113,0,18,1,IGFN1;immunoglobulin-like and fibronectin type III domain containing 1,GO:0030018//Z disc;GO:0005634//nucleus,-,-,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
9117,3,107,4,80,351,44,0,0,58,0,107,0,SEC22C;SEC22 vesicle trafficking protein homolog C (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0005789//endoplasmic reticulum membrane,GO:0015031//protein transport;GO:0006888//ER to Golgi vesicle-mediated transport,-,-
91179,0,0,0,0,0,0,2,9,56,0,0,0,"SCARF2;scavenger receptor class F, member 2",GO:0016021//integral component of membrane;GO:0005925//focal adhesion,GO:0007155//cell adhesion,GO:0005515//protein binding,K06252//ECM-receptor interaction;Focal adhesion
9118,0,0,0,0,0,23,22,0,0,0,0,0,"INA;internexin neuronal intermediate filament protein, alpha",GO:0005615//extracellular space;GO:0005883//neurofilament,GO:0030154//cell differentiation;GO:0021762//substantia nigra development;GO:0060052//neurofilament cytoskeleton organization,GO:0005200//structural constituent of cytoskeleton,-
91181,121,0,0,0,0,7,10,0,86,0,34,0,NUP210L;nucleoporin 210kDa-like,GO:0016021//integral component of membrane,GO:0060009//Sertoli cell development;GO:0007286//spermatid development,-,K14314//RNA transport
9119,0,0,0,0,0,31,18,0,29,0,0,0,KRT75;keratin 75,GO:0045095//keratin filament;GO:0070062//extracellular vesicular exosome,GO:0002244//hematopoietic progenitor cell differentiation,GO:0005198//structural molecule activity,-
912,0,0,0,0,0,0,17,0,59,0,0,0,CD1D;CD1d molecule,GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm;GO:0005765//lysosomal membrane,"GO:0048006//antigen processing and presentation, endogenous lipid antigen via MHC class Ib;GO:0016045//detection of bacterium;GO:0016032//viral process;GO:0045087//innate immune response;GO:0042102//positive regulation of T cell proliferation;GO:0034113//heterotypic cell-cell adhesion;GO:0045089//positive regulation of innate immune response;GO:0045058//T cell selection",GO:0004872//receptor activity;GO:0030884//exogenous lipid antigen binding;GO:0042393//histone binding;GO:0030881//beta-2-microglobulin binding;GO:0050839//cell adhesion molecule binding,K06448//Hematopoietic cell lineage;Amoebiasis
9120,0,0,0,0,0,25,0,0,30,0,0,0,"SLC16A6;solute carrier family 16, member 6",GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity,-
9121,115,0,0,0,23,0,27,0,10,0,0,0,"SLC16A5;solute carrier family 16 (monocarboxylate transporter), member 5",GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport,GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity;GO:0015355//secondary active monocarboxylate transmembrane transporter activity,-
9122,296,0,0,0,16,0,0,1,19,0,0,0,"SLC16A4;solute carrier family 16, member 4",GO:0005887//integral component of plasma membrane;GO:0016020//membrane,GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity;GO:0008028//monocarboxylic acid transmembrane transporter activity,-
91227,0,0,0,0,0,20,0,0,15,0,0,0,GGTLC2;gamma-glutamyltransferase light chain 2,GO:0031362//anchored component of external side of plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0019370//leukotriene biosynthetic process;GO:0006749//glutathione metabolic process,GO:0003840//gamma-glutamyltransferase activity,K00681//Cyanoamino acid metabolism;Glutathione metabolism;Taurine and hypotaurine metabolism;Metabolic pathways;Arachidonic acid metabolism
9123,122,0,0,0,0,24,1,0,43,0,0,363,"SLC16A3;solute carrier family 16 (monocarboxylate transporter), member 3",GO:0016020//membrane;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane;GO:0031965//nuclear membrane;GO:0005887//integral component of plasma membrane,GO:0007596//blood coagulation;GO:0006090//pyruvate metabolic process;GO:0015718//monocarboxylic acid transport;GO:0055085//transmembrane transport;GO:0044237//cellular metabolic process;GO:0050900//leukocyte migration;GO:0044281//small molecule metabolic process,GO:0015355//secondary active monocarboxylate transmembrane transporter activity;GO:0044822//poly(A) RNA binding;GO:0008028//monocarboxylic acid transmembrane transporter activity;GO:0015293//symporter activity,-
9124,0,0,1,0,11,0,11,0,16,0,8,532,PDLIM1;PDZ and LIM domain 1,GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005667//transcription factor complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006979//response to oxidative stress;GO:0001666//response to hypoxia",GO:0008270//zinc ion binding;GO:0003713//transcription coactivator activity,K03426//Peroxisome;Nicotinate and nicotinamide metabolism
9125,0,0,0,18,11,20,28,0,20,0,10,0,RQCD1;RCD1 required for cell differentiation1 homolog (S. pombe),GO:0005829//cytosol;GO:0016020//membrane;GO:0005634//nucleus;GO:0000932//cytoplasmic mRNA processing body;GO:0030014//CCR4-NOT complex,"GO:0016071//mRNA metabolic process;GO:0007548//sex differentiation;GO:0016070//RNA metabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:2000327//positive regulation of ligand-dependent nuclear receptor transcription coactivator activity;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0031047//gene silencing by RNA;GO:0006417//regulation of translation;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0019221//cytokine-mediated signaling pathway;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding,K12606//RNA degradation
91252,0,0,0,0,0,3,38,12,13,0,0,0,"SLC39A13;solute carrier family 39 (zinc transporter), member 13",GO:0048471//perinuclear region of cytoplasm;GO:0005794//Golgi apparatus;GO:0030173//integral component of Golgi membrane;GO:0016021//integral component of membrane,GO:0006882//cellular zinc ion homeostasis;GO:0071577//zinc ion transmembrane transport;GO:0061448//connective tissue development,GO:0005385//zinc ion transmembrane transporter activity;GO:0042803//protein homodimerization activity,-
9126,0,0,1,30,59,0,0,0,42,262,11,0,SMC3;structural maintenance of chromosomes 3,"GO:0008280//cohesin core heterodimer;GO:0005654//nucleoplasm;GO:0034991//nuclear meiotic cohesin complex;GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0000922//spindle pole;GO:0000785//chromatin;GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0030893//meiotic cohesin complex;GO:0008278//cohesin complex;GO:0005694//chromosome;GO:0005829//cytosol;GO:0005604//basement membrane;GO:0016363//nuclear matrix;GO:0000800//lateral element",GO:0007052//mitotic spindle organization;GO:0019827//stem cell maintenance;GO:0000278//mitotic cell cycle;GO:0007064//mitotic sister chromatid cohesion;GO:0007062//sister chromatid cohesion;GO:0007126//meiotic nuclear division;GO:0007165//signal transduction;GO:0006275//regulation of DNA replication;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0032876//negative regulation of DNA endoreduplication,GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0036033//mediator complex binding;GO:0046982//protein heterodimerization activity;GO:0045502//dynein binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding,K06669//Cell cycle;Cell cycle - yeast;Meiosis - yeast;Oocyte meiosis
9127,0,0,0,0,0,0,0,1,5,0,7,0,"P2RX6;purinergic receptor P2X, ligand-gated ion channel, 6",GO:0030054//cell junction;GO:0005887//integral component of plasma membrane;GO:0014069//postsynaptic density;GO:0043197//dendritic spine;GO:0005639//integral component of nuclear inner membrane;GO:0005737//cytoplasm;GO:0043025//neuronal cell body,GO:0051291//protein heterooligomerization;GO:0055085//transmembrane transport;GO:0006936//muscle contraction;GO:0035590//purinergic nucleotide receptor signaling pathway;GO:0006810//transport;GO:0006812//cation transport;GO:0007165//signal transduction;GO:0051260//protein homooligomerization,GO:0005524//ATP binding;GO:0004931//extracellular ATP-gated cation channel activity;GO:0001614//purinergic nucleotide receptor activity;GO:0015267//channel activity;GO:0004888//transmembrane signaling receptor activity;GO:0042802//identical protein binding,K05221//Neuroactive ligand-receptor interaction;Calcium signaling pathway
91272,0,0,0,14,0,0,0,4,30,0,0,0,BOD1;biorientation of chromosomes in cell division 1,GO:0005737//cytoplasm;GO:0005815//microtubule organizing center;GO:0000777//condensed chromosome kinetochore,GO:0007067//mitotic nuclear division,-,-
9128,0,0,0,0,29,13,0,0,1,0,13,0,PRPF4;pre-mRNA processing factor 4,GO:0016607//nuclear speck;GO:0071001//U4/U6 snRNP;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005634//nucleus,"GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0006396//RNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0005515//protein binding,K12662//Spliceosome
91283,0,33,0,7,20,0,0,0,24,0,0,0,MSANTD3;Myb/SANT-like DNA-binding domain containing 3,-,-,-,-
91289,0,0,0,0,0,0,0,0,24,1,3,0,LMF2;lipase maturation factor 2,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,-,-,-
9129,0,0,0,0,19,0,0,0,0,0,0,89,PRPF3;pre-mRNA processing factor 3,GO:0016607//nuclear speck;GO:0005681//spliceosomal complex;GO:0005730//nucleolus;GO:0046540//U4/U6 x U5 tri-snRNP complex;GO:0015030//Cajal body;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions",GO:0042802//identical protein binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12843//Spliceosome
91298,0,0,0,18,10,31,31,0,0,0,14,0,C12orf29;chromosome 12 open reading frame 29,-,GO:0002244//hematopoietic progenitor cell differentiation,-,-
913,88,0,0,0,0,0,0,0,24,0,0,0,CD1E;CD1e molecule,GO:0043202//lysosomal lumen;GO:0005887//integral component of plasma membrane;GO:0005769//early endosome;GO:0000139//Golgi membrane;GO:0005770//late endosome,GO:0006955//immune response;GO:0019882//antigen processing and presentation,GO:0008289//lipid binding,K06448//Amoebiasis;Hematopoietic cell lineage
9130,0,0,0,9,36,0,0,5,0,0,0,0,"FAM50A;family with sequence similarity 50, member A",GO:0005634//nucleus,GO:0007283//spermatogenesis,GO:0044822//poly(A) RNA binding,-
91300,0,0,1,0,8,5,0,0,14,0,0,0,R3HDM4;R3H domain containing 4,GO:0005634//nucleus,-,GO:0003676//nucleic acid binding,-
91304,0,0,0,0,0,4,6,0,17,0,0,0,TMEM259;transmembrane protein 259,GO:0016021//integral component of membrane;GO:0005737//cytoplasm,-,-,K06270//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Focal adhesion;Long-term potentiation
9131,0,0,0,5,1,0,0,0,16,78,4,0,"AIFM1;apoptosis-inducing factor, mitochondrion-associated, 1",GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005758//mitochondrial intermembrane space;GO:0005743//mitochondrial inner membrane;GO:0005739//mitochondrion;GO:0005829//cytosol,GO:0045454//cell redox homeostasis;GO:0006309//apoptotic DNA fragmentation;GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process;GO:0055114//oxidation-reduction process;GO:0030182//neuron differentiation;GO:0051402//neuron apoptotic process;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006308//DNA catabolic process;GO:0030261//chromosome condensation;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:1902510//regulation of apoptotic DNA fragmentation;GO:0032981//mitochondrial respiratory chain complex I assembly,"GO:0071949//FAD binding;GO:0005515//protein binding;GO:0003677//DNA binding;GO:0016174//NAD(P)H oxidase activity;GO:0009055//electron carrier activity;GO:0046983//protein dimerization activity;GO:0016651//oxidoreductase activity, acting on NAD(P)H",K04727//Apoptosis
91316,0,0,0,0,9,23,72,40,11,103,1,0,"GUSBP11;glucuronidase, beta pseudogene 11",-,-,-,K06554//Primary immunodeficiency;K01195//Pentose and glucuronate interconversions;Metabolic pathways;Glycosaminoglycan degradation;Porphyrin and chlorophyll metabolism;Lysosome;Drug metabolism - other enzymes;Starch and sucrose metabolism
91319,0,0,0,0,0,7,0,0,14,0,0,0,DERL3;derlin 3,GO:0030176//integral component of endoplasmic reticulum membrane,GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0018279//protein N-linked glycosylation via asparagine,GO:0005515//protein binding,K13989//Protein processing in endoplasmic reticulum
9132,0,0,1,0,3,0,0,19,6,0,33,0,"KCNQ4;potassium voltage-gated channel, KQT-like subfamily, member 4",GO:0005886//plasma membrane;GO:0008076//voltage-gated potassium channel complex;GO:0009925//basal plasma membrane,GO:0006813//potassium ion transport;GO:0007605//sensory perception of sound;GO:0042472//inner ear morphogenesis;GO:0071805//potassium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission,GO:0005251//delayed rectifier potassium channel activity;GO:0005267//potassium channel activity,K04929//Cholinergic synapse
9133,0,0,0,6,39,0,0,0,0,0,0,0,CCNB2;cyclin B2,GO:0015630//microtubule cytoskeleton;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0016020//membrane;GO:0005829//cytosol,GO:0007067//mitotic nuclear division;GO:0043029//T cell homeostasis;GO:0007077//mitotic nuclear envelope disassembly;GO:0001701//in utero embryonic development;GO:0048538//thymus development;GO:0040007//growth;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding;GO:0005515//protein binding,K05868//Progesterone-mediated oocyte maturation;Cell cycle;p53 signaling pathway;HTLV-I infection;Oocyte meiosis
9134,6,0,0,13,1,0,0,0,0,0,0,0,CCNE2;cyclin E2,GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0000075//cell cycle checkpoint;GO:0051301//cell division;GO:0006270//DNA replication initiation;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity,K06626//Pathways in cancer;Oocyte meiosis;p53 signaling pathway;Prostate cancer;Measles;Small cell lung cancer;Cell cycle
9135,0,96,2,120,517,0,0,0,24,1,27,0,"RABEP1;rabaptin, RAB GTPase binding effector protein 1",GO:0055037//recycling endosome;GO:0043231//intracellular membrane-bounded organelle;GO:0030139//endocytic vesicle;GO:0005768//endosome;GO:0005769//early endosome,GO:0006915//apoptotic process;GO:0061025//membrane fusion;GO:0006897//endocytosis;GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport,GO:0005096//GTPase activator activity;GO:0008083//growth factor activity;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K12480//Endocytosis
91351,59,19,0,25,0,0,24,56,85,0,0,0,DDX60L;DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like,-,GO:0008152//metabolic process,GO:0004386//helicase activity;GO:0003723//RNA binding;GO:0005524//ATP binding,K12599//RNA degradation;K12598//RNA degradation;K01529//Purine metabolism
91353,0,0,0,0,0,18,0,53,0,0,0,0,"IGLL3P;immunoglobulin lambda-like polypeptide 3, pseudogene",-,-,-,K06554//Primary immunodeficiency
91355,7,0,47,0,0,1,37,0,45,141,2,323,LRP5L;low density lipoprotein receptor-related protein 5-like,-,GO:0060070//canonical Wnt signaling pathway;GO:0044332//Wnt signaling pathway involved in dorsal/ventral axis specification,GO:0042813//Wnt-activated receptor activity;GO:0017147//Wnt-protein binding,K03068//Wnt signaling pathway
9136,158,0,0,0,1,10,59,0,65,0,3,0,"RRP9;ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)",GO:0005730//nucleolus;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005634//nucleus;GO:0005732//small nucleolar ribonucleoprotein complex,GO:0006364//rRNA processing,GO:0044822//poly(A) RNA binding,-
91368,0,0,0,0,28,0,0,0,25,0,7,0,CDKN2AIPNL;CDKN2A interacting protein N-terminal like,-,-,-,K01539//Aldosterone-regulated sodium reabsorption;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
91369,0,12,1,44,105,0,48,0,8,0,6,0,ANKRD40;ankyrin repeat domain 40,-,-,-,K11447//Transcriptional misregulation in cancer;K01539//Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Oxidative phosphorylation;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways
91373,0,20,0,8,1,0,14,0,25,0,9,0,UAP1L1;UDP-N-acteylglucosamine pyrophosphorylase 1-like 1,-,GO:0008152//metabolic process,-,K00972//Amino sugar and nucleotide sugar metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
9138,0,0,0,0,2,13,0,47,29,0,3,0,ARHGEF1;Rho guanine nucleotide exchange factor (GEF) 1,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008283//cell proliferation;GO:0032321//positive regulation of Rho GTPase activity;GO:0050770//regulation of axonogenesis;GO:0050771//negative regulation of axonogenesis;GO:0007266//Rho protein signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway,GO:0005096//GTPase activator activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K12330//Vascular smooth muscle contraction;Regulation of actin cytoskeleton
9139,0,53,1,37,111,28,28,76,91,0,30,135,"CBFA2T2;core-binding factor, runt domain, alpha subunit 2; translocated to, 2",GO:0005634//nucleus,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0030855//epithelial cell differentiation;GO:0010977//negative regulation of neuron projection development;GO:0010976//positive regulation of neuron projection development",GO:0003714//transcription corepressor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K10053//Acute myeloid leukemia;Pathways in cancer;Transcriptional misregulation in cancer
91392,0,0,0,0,0,15,37,0,16,0,0,0,ZNF502;zinc finger protein 502,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
914,0,0,0,0,0,6,37,0,0,0,0,0,CD2;CD2 molecule,GO:0005911//cell-cell junction;GO:0009986//cell surface;GO:0009898//cytoplasmic side of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane;GO:0046658//anchored component of plasma membrane,GO:0050900//leukocyte migration;GO:0032760//positive regulation of tumor necrosis factor production;GO:0045580//regulation of T cell differentiation;GO:1902715//positive regulation of interferon-gamma secretion;GO:0042110//T cell activation;GO:0016337//single organismal cell-cell adhesion;GO:0030887//positive regulation of myeloid dendritic cell activation;GO:0030101//natural killer cell activation;GO:0001766//membrane raft polarization;GO:2000484//positive regulation of interleukin-8 secretion;GO:0034113//heterotypic cell-cell adhesion;GO:0006915//apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0007596//blood coagulation,GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0005102//receptor binding;GO:0004872//receptor activity,K06449//Hematopoietic cell lineage;Cell adhesion molecules (CAMs)
9140,69,34,0,1,23,0,0,0,16,0,0,0,ATG12;autophagy related 12,GO:0034274//Atg12-Atg5-Atg16 complex;GO:0034045//pre-autophagosomal structure membrane,GO:0006501//C-terminal protein lipidation;GO:0032480//negative regulation of type I interferon production;GO:0006995//cellular response to nitrogen starvation;GO:0000422//mitochondrion degradation;GO:0000045//autophagic vacuole assembly;GO:0045087//innate immune response,GO:0019776//Atg8 ligase activity;GO:0005515//protein binding,K08336//Regulation of autophagy;RIG-I-like receptor signaling pathway
91404,0,0,0,0,38,38,48,0,29,0,0,0,SESTD1;SEC14 and spectrin domains 1,GO:0034704//calcium channel complex,-,"GO:0005515//protein binding;GO:0001786//phosphatidylserine binding;GO:0080025//phosphatidylinositol-3,5-bisphosphate binding;GO:0031210//phosphatidylcholine binding;GO:0070300//phosphatidic acid binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding;GO:0032266//phosphatidylinositol-3-phosphate binding;GO:0010314//phosphatidylinositol-5-phosphate binding;GO:0070273//phosphatidylinositol-4-phosphate binding;GO:0005545//1-phosphatidylinositol binding;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding",-
91408,0,3,1,27,119,0,0,0,79,0,0,0,BTF3L4;basic transcription factor 3-like 4,-,-,-,-
91409,0,0,0,6,0,17,0,0,12,0,0,0,CCDC74B;coiled-coil domain containing 74B,-,-,-,-
9141,0,0,0,0,13,0,0,0,0,0,0,0,PDCD5;programmed cell death 5,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0043065//positive regulation of apoptotic process;GO:0006915//apoptotic process,GO:0003677//DNA binding,-
91419,0,0,0,0,20,10,0,0,12,0,0,0,XRCC6BP1;XRCC6 binding protein 1,GO:0005958//DNA-dependent protein kinase-DNA ligase 4 complex,GO:0006468//protein phosphorylation;GO:0006508//proteolysis;GO:0006303//double-strand break repair via nonhomologous end joining,GO:0004222//metalloendopeptidase activity;GO:0004677//DNA-dependent protein kinase activity;GO:0046872//metal ion binding,-
9142,0,0,0,0,0,0,0,0,9,0,0,0,TMEM257;transmembrane protein 257,GO:0016021//integral component of membrane,-,-,-
9143,0,0,0,0,0,0,15,0,0,0,2,0,SYNGR3;synaptogyrin 3,GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0030054//cell junction;GO:0031594//neuromuscular junction,GO:0032411//positive regulation of transporter activity;GO:0021762//substantia nigra development,GO:0042169//SH2 domain binding;GO:0047485//protein N-terminus binding,K04403//NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway;Leishmaniasis;Osteoclast differentiation;Toxoplasmosis;Herpes simplex infection;MAPK signaling pathway;Epstein-Barr virus infection
91433,6,0,0,0,4,10,15,0,57,0,2,0,RCCD1;RCC1 domain containing 1,GO:0005737//cytoplasm;GO:0005886//plasma membrane,-,-,K10595//Ubiquitin mediated proteolysis;K10615//Ubiquitin mediated proteolysis
9144,0,0,0,0,1,0,14,0,36,4,7,1,SYNGR2;synaptogyrin 2,GO:0016021//integral component of membrane;GO:0008021//synaptic vesicle;GO:0070062//extracellular vesicular exosome,GO:0006605//protein targeting,-,K04403//Epstein-Barr virus infection;Osteoclast differentiation;Toxoplasmosis;Leishmaniasis;MAPK signaling pathway;Herpes simplex infection;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway;NF-kappa B signaling pathway
91445,0,40,1,76,160,32,0,3,17,0,14,0,RNF185;ring finger protein 185,GO:0016021//integral component of membrane;GO:0005741//mitochondrial outer membrane;GO:0005789//endoplasmic reticulum membrane,GO:0016567//protein ubiquitination;GO:0006914//autophagy,GO:0008270//zinc ion binding;GO:0016874//ligase activity,K10666//Protein processing in endoplasmic reticulum
9145,50,1,0,0,0,0,5,54,24,1,2,0,SYNGR1;synaptogyrin 1,GO:0042470//melanosome;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane,GO:0048172//regulation of short-term neuronal synaptic plasticity;GO:0006605//protein targeting;GO:0048169//regulation of long-term neuronal synaptic plasticity,-,K04403//Toxoplasmosis;Leishmaniasis;Osteoclast differentiation;MAPK signaling pathway;Herpes simplex infection;Epstein-Barr virus infection;NF-kappa B signaling pathway;NOD-like receptor signaling pathway;Toll-like receptor signaling pathway
91452,0,0,0,5,0,0,0,0,0,0,0,0,ACBD5;acyl-CoA binding domain containing 5,GO:0005634//nucleus;GO:0005777//peroxisome;GO:0005778//peroxisomal membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006810//transport;GO:0016236//macroautophagy;GO:0035973//aggrephagy,GO:0008289//lipid binding;GO:0000062//fatty-acyl-CoA binding,K08762//PPAR signaling pathway;K13239//Peroxisome;Fatty acid metabolism
9146,0,46,1,19,55,0,0,1,38,0,49,0,HGS;hepatocyte growth factor-regulated tyrosine kinase substrate,GO:0032585//multivesicular body membrane;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0030141//secretory granule;GO:0043231//intracellular membrane-bounded organelle;GO:0031901//early endosome membrane,GO:0046426//negative regulation of JAK-STAT cascade;GO:0008333//endosome to lysosome transport;GO:0042176//regulation of protein catabolic process;GO:0072657//protein localization to membrane;GO:0010324//membrane invagination;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0010628//positive regulation of gene expression;GO:0061024//membrane organization;GO:0008285//negative regulation of cell proliferation;GO:0006622//protein targeting to lysosome;GO:0016197//endosomal transport;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0007165//signal transduction,GO:0019904//protein domain specific binding;GO:0046872//metal ion binding;GO:0005515//protein binding,K12182//Endocytosis;Phagosome
91461,0,0,0,0,0,0,0,5,58,0,0,0,"PKDCC;protein kinase domain containing, cytoplasmic",GO:0005794//Golgi apparatus,GO:0060021//palate development;GO:0048566//embryonic digestive tract development;GO:0030282//bone mineralization;GO:0006468//protein phosphorylation;GO:0015031//protein transport;GO:0001501//skeletal system development;GO:0035264//multicellular organism growth;GO:0042997//negative regulation of Golgi to plasma membrane protein transport;GO:0030501//positive regulation of bone mineralization;GO:0048286//lung alveolus development;GO:0032332//positive regulation of chondrocyte differentiation;GO:0030154//cell differentiation,GO:0005524//ATP binding;GO:0004672//protein kinase activity,-
9147,0,0,0,0,1,0,0,0,0,0,0,0,NEMF;nuclear export mediator factor,GO:0005634//nucleus,GO:0051168//nuclear export,-,-
9148,0,0,0,0,21,25,0,0,18,0,0,0,NEURL1;neuralized E3 ubiquitin protein ligase 1,GO:0005886//plasma membrane;GO:0097440//apical dendrite;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043197//dendritic spine;GO:0014069//postsynaptic density;GO:0043204//perikaryon;GO:0048471//perinuclear region of cytoplasm,GO:0045741//positive regulation of epidermal growth factor-activated receptor activity;GO:0048170//positive regulation of long-term neuronal synaptic plasticity;GO:0007420//brain development;GO:0006417//regulation of translation;GO:0006513//protein monoubiquitination;GO:0030317//sperm motility;GO:0007288//sperm axoneme assembly;GO:0008285//negative regulation of cell proliferation;GO:0090129//positive regulation of synapse maturation;GO:0071230//cellular response to amino acid stimulus;GO:0060999//positive regulation of dendritic spine development;GO:0007519//skeletal muscle tissue development;GO:0043065//positive regulation of apoptotic process;GO:0007399//nervous system development;GO:0045746//negative regulation of Notch signaling pathway;GO:0007595//lactation;GO:0051491//positive regulation of filopodium assembly;GO:0007219//Notch signaling pathway,"GO:0045183//translation factor activity, non-nucleic acid binding;GO:0008270//zinc ion binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity",-
9149,0,0,1,0,0,0,0,0,15,126,0,0,DYRK1B;dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B,GO:0005634//nucleus,"GO:0060612//adipose tissue development;GO:0006468//protein phosphorylation;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0007520//myoblast fusion;GO:0045893//positive regulation of transcription, DNA-templated",GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0004713//protein tyrosine kinase activity;GO:0003713//transcription coactivator activity;GO:0005524//ATP binding,-
9150,107,1,0,6,0,14,0,0,0,84,7,0,"CTDP1;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1",GO:0005654//nucleoplasm;GO:0005819//spindle;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0051233//spindle midzone;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0005730//nucleolus,GO:0006470//protein dephosphorylation;GO:0006368//transcription elongation from RNA polymerase II promoter;GO:0016032//viral process;GO:0010458//exit from mitosis;GO:0006366//transcription from RNA polymerase II promoter;GO:0050434//positive regulation of viral transcription;GO:0010467//gene expression,GO:0003899//DNA-directed RNA polymerase activity;GO:0008420//CTD phosphatase activity,-
9152,0,0,0,0,0,2,40,48,19,0,10,0,"SLC6A5;solute carrier family 6 (neurotransmitter transporter), member 5",GO:0016021//integral component of membrane;GO:0005886//plasma membrane,"GO:0055085//transmembrane transport;GO:0060012//synaptic transmission, glycinergic;GO:0007268//synaptic transmission;GO:0036233//glycine import;GO:0006836//neurotransmitter transport;GO:0006810//transport",GO:0005328//neurotransmitter:sodium symporter activity;GO:0015375//glycine:sodium symporter activity,-
91522,0,0,0,0,7,0,37,0,73,263,8,0,"COL23A1;collagen, type XXIII, alpha 1",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005581//collagen trimer;GO:0005788//endoplasmic reticulum lumen,GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0030198//extracellular matrix organization,-,K06236//ECM-receptor interaction;Focal adhesion;Amoebiasis;Protein digestion and absorption
91523,0,0,0,0,0,3,0,112,23,0,12,0,PCED1B;PC-esterase domain containing 1B,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
91526,0,0,0,0,0,38,56,0,31,0,6,327,ANKRD44;ankyrin repeat domain 44,-,-,GO:0005515//protein binding,-
9153,79,0,0,0,0,0,0,69,30,29,0,0,"SLC28A2;solute carrier family 28 (concentrative nucleoside transporter), member 2",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016020//membrane,GO:0015860//purine nucleoside transmembrane transport;GO:0006139//nucleobase-containing compound metabolic process;GO:0055085//transmembrane transport,GO:0005415//nucleoside:sodium symporter activity;GO:0001882//nucleoside binding;GO:0015211//purine nucleoside transmembrane transporter activity,-
9154,62,0,0,0,0,0,0,0,54,158,1,0,"SLC28A1;solute carrier family 28 (concentrative nucleoside transporter), member 1",GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0055085//transmembrane transport;GO:1901642//nucleoside transmembrane transport;GO:0006139//nucleobase-containing compound metabolic process,GO:0005337//nucleoside transmembrane transporter activity;GO:0001882//nucleoside binding;GO:0005415//nucleoside:sodium symporter activity,-
91543,77,0,0,0,13,23,13,0,27,0,2,0,RSAD2;radical S-adenosyl methionine domain containing 2,GO:0005789//endoplasmic reticulum membrane;GO:0005743//mitochondrial inner membrane;GO:0005794//Golgi apparatus;GO:0005741//mitochondrial outer membrane;GO:0005783//endoplasmic reticulum;GO:0005811//lipid particle;GO:0005739//mitochondrion,"GO:0008152//metabolic process;GO:0009615//response to virus;GO:0035710//CD4-positive, alpha-beta T cell activation;GO:0050709//negative regulation of protein secretion;GO:0043367//CD4-positive, alpha-beta T cell differentiation;GO:0045071//negative regulation of viral genome replication;GO:0030278//regulation of ossification;GO:0034165//positive regulation of toll-like receptor 9 signaling pathway;GO:0034157//positive regulation of toll-like receptor 7 signaling pathway;GO:2000553//positive regulation of T-helper 2 cell cytokine production;GO:0051607//defense response to virus;GO:0016032//viral process;GO:0045087//innate immune response;GO:0001503//ossification","GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043621//protein self-association;GO:0051539//4 iron, 4 sulfur cluster binding;GO:0003824//catalytic activity",K15045//Influenza A
91544,1,37,0,1,0,0,18,0,13,0,0,0,UBXN11;UBX domain protein 11,GO:0005856//cytoskeleton;GO:0005737//cytoplasm,-,-,K14012//Protein processing in endoplasmic reticulum
9156,29,0,0,0,0,0,45,0,19,39,0,0,EXO1;exonuclease 1,GO:0005634//nucleus,"GO:0090502//RNA phosphodiester bond hydrolysis, endonucleolytic;GO:0006298//mismatch repair;GO:0045190//isotype switching;GO:0090305//nucleic acid phosphodiester bond hydrolysis;GO:0006281//DNA repair;GO:0016446//somatic hypermutation of immunoglobulin genes;GO:0006310//DNA recombination;GO:0007126//meiotic nuclear division;GO:0000737//DNA catabolic process, endonucleolytic;GO:0000738//DNA catabolic process, exonucleolytic;GO:0002455//humoral immune response mediated by circulating immunoglobulin",GO:0004523//RNA-DNA hybrid ribonuclease activity;GO:0045145//single-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0008409//5'-3' exonuclease activity;GO:0051908//double-stranded DNA 5'-3' exodeoxyribonuclease activity;GO:0003677//DNA binding;GO:0004527//exonuclease activity;GO:0043566//structure-specific DNA binding;GO:0048256//flap endonuclease activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K10746//Mismatch repair
91574,0,112,0,23,53,0,19,84,13,0,19,0,C12orf65;chromosome 12 open reading frame 65,GO:0005739//mitochondrion,GO:0006415//translational termination;GO:0008219//cell death,GO:0003747//translation release factor activity,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis
9158,0,23,2,0,18,0,0,0,0,74,7,0,FIBP;fibroblast growth factor (acidic) intracellular binding protein,GO:0016020//membrane;GO:0005739//mitochondrion;GO:0012505//endomembrane system;GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,GO:0070527//platelet aggregation;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0017134//fibroblast growth factor binding,-
91582,0,0,0,5,19,0,0,0,0,0,0,0,RPS19BP1;ribosomal protein S19 binding protein 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0019899//enzyme binding,-
91584,0,9,17,0,0,29,30,73,254,333,17,0,PLXNA4;plexin A4,GO:0016021//integral component of membrane;GO:0002116//semaphorin receptor complex;GO:0005622//intracellular;GO:0005886//plasma membrane,GO:0021615//glossopharyngeal nerve morphogenesis;GO:0021793//chemorepulsion of branchiomotor axon;GO:0007411//axon guidance;GO:0071526//semaphorin-plexin signaling pathway;GO:0021612//facial nerve structural organization;GO:0050923//regulation of negative chemotaxis;GO:0021644//vagus nerve morphogenesis;GO:0048485//sympathetic nervous system development;GO:0021960//anterior commissure morphogenesis;GO:0048841//regulation of axon extension involved in axon guidance;GO:0021784//postganglionic parasympathetic nervous system development,GO:0017154//semaphorin receptor activity,K06820//Axon guidance
9159,52,0,0,18,0,0,22,9,51,0,0,0,PCSK7;proprotein convertase subtilisin/kexin type 7,GO:0030173//integral component of Golgi membrane,GO:0006508//proteolysis;GO:0016486//peptide hormone processing;GO:0016485//protein processing,GO:0008233//peptidase activity;GO:0004252//serine-type endopeptidase activity,-
916,0,0,0,0,0,0,0,0,8,0,0,0,"CD3E;CD3e molecule, epsilon (CD3-TCR complex)",GO:0042101//T cell receptor complex;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0001772//immunological synapse;GO:0005911//cell-cell junction;GO:0042105//alpha-beta T cell receptor complex;GO:0005887//integral component of plasma membrane,GO:0002669//positive regulation of T cell anergy;GO:0042981//regulation of apoptotic process;GO:0042102//positive regulation of T cell proliferation;GO:0050776//regulation of immune response;GO:0050850//positive regulation of calcium-mediated signaling;GO:0097190//apoptotic signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050852//T cell receptor signaling pathway;GO:0007584//response to nutrient;GO:0007166//cell surface receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0007172//signal complex assembly;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0006461//protein complex assembly;GO:0032753//positive regulation of interleukin-4 production;GO:0045060//negative thymic T cell selection;GO:0031295//T cell costimulation;GO:0032729//positive regulation of interferon-gamma production;GO:0045879//negative regulation of smoothened signaling pathway;GO:0035556//intracellular signal transduction;GO:0007186//G-protein coupled receptor signaling pathway;GO:0042110//T cell activation,GO:0042608//T cell receptor binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0030159//receptor signaling complex scaffold activity;GO:0017124//SH3 domain binding;GO:0019901//protein kinase binding;GO:0005057//receptor signaling protein activity;GO:0004888//transmembrane signaling receptor activity,K06451//Primary immunodeficiency;Chagas disease (American trypanosomiasis);T cell receptor signaling pathway;Hematopoietic cell lineage;HTLV-I infection;Measles
91603,0,0,0,0,20,0,0,0,10,0,0,0,ZNF830;zinc finger protein 830,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005730//nucleolus,GO:0033260//nuclear cell cycle DNA replication;GO:0007067//mitotic nuclear division;GO:0001832//blastocyst growth,GO:0046872//metal ion binding;GO:0005515//protein binding,-
91607,0,0,0,7,0,0,0,0,22,0,0,0,SLFN11;schlafen family member 11,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:2000134//negative regulation of G1/S transition of mitotic cell cycle;GO:0051607//defense response to virus,GO:0005524//ATP binding;GO:0000049//tRNA binding,-
91608,0,38,0,0,0,21,22,0,0,0,10,0,"RASL10B;RAS-like, family 10, member B",GO:0005886//plasma membrane,GO:0090277//positive regulation of peptide hormone secretion;GO:0003050//regulation of systemic arterial blood pressure by atrial natriuretic peptide;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0005525//GTP binding,-
91612,0,41,0,30,39,1,0,0,32,0,0,0,CHURC1;churchill domain containing 1,-,"GO:0045893//positive regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0007275//multicellular organismal development",GO:0008270//zinc ion binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K05954//Terpenoid backbone biosynthesis
91614,0,0,0,0,0,4,1,0,0,0,0,0,DEPDC7;DEP domain containing 7,GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,-,-
9162,0,0,1,0,0,33,17,49,47,0,9,0,"DGKI;diacylglycerol kinase, iota",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0032045//guanyl-nucleotide exchange factor complex;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0032317//regulation of Rap GTPase activity;GO:0035556//intracellular signal transduction;GO:0043086//negative regulation of catalytic activity;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:0016310//phosphorylation;GO:0046579//positive regulation of Ras protein signal transduction;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004143//diacylglycerol kinase activity;GO:0003951//NAD+ kinase activity;GO:0005095//GTPase inhibitor activity;GO:0017016//Ras GTPase binding;GO:0005524//ATP binding,K00901//Metabolic pathways;Phosphatidylinositol signaling system;Glycerolipid metabolism;Glycerophospholipid metabolism
91624,0,0,0,0,0,29,0,0,19,0,0,0,NEXN;nexilin (F actin binding protein),GO:0030018//Z disc;GO:0005856//cytoskeleton;GO:0005925//focal adhesion,GO:0051493//regulation of cytoskeleton organization;GO:0042981//regulation of apoptotic process;GO:0030334//regulation of cell migration;GO:0006468//protein phosphorylation;GO:0048739//cardiac muscle fiber development,GO:0008307//structural constituent of muscle;GO:0004683//calmodulin-dependent protein kinase activity;GO:0051015//actin filament binding,K00907//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Gastric acid secretion;Calcium signaling pathway;Focal adhesion
91646,0,0,26,11,36,10,0,86,76,0,0,0,TDRD12;tudor domain containing 12,-,GO:0009566//fertilization;GO:0007283//spermatogenesis;GO:0007275//multicellular organismal development;GO:0030154//cell differentiation;GO:0031047//gene silencing by RNA;GO:0007140//male meiosis;GO:0034587//piRNA metabolic process;GO:0043046//DNA methylation involved in gamete generation,GO:0004386//helicase activity;GO:0003676//nucleic acid binding;GO:0005524//ATP binding,-
91647,0,0,0,0,9,0,0,0,9,0,0,0,ATPAF2;ATP synthase mitochondrial F1 complex assembly factor 2,GO:0005739//mitochondrion;GO:0016607//nuclear speck,GO:0043461//proton-transporting ATP synthase complex assembly,GO:0005515//protein binding,-
9166,0,0,0,0,14,0,0,0,14,0,0,0,"EBAG9;estrogen receptor binding site associated, antigen, 9",GO:0005794//Golgi apparatus;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0030141//secretory granule;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0001558//regulation of cell growth;GO:0006915//apoptotic process,GO:0016505//peptidase activator activity involved in apoptotic process,-
91661,0,0,0,14,14,23,23,8,26,0,0,0,ZNF765;zinc finger protein 765,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
91662,0,0,0,0,0,0,0,46,46,0,18,0,"NLRP12;NLR family, pyrin domain containing 12",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0045409//negative regulation of interleukin-6 biosynthetic process;GO:0045345//positive regulation of MHC class I biosynthetic process;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050711//negative regulation of interleukin-1 secretion;GO:1901223//negative regulation of NIK/NF-kappaB signaling;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045751//negative regulation of Toll signaling pathway;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0036336//dendritic cell migration;GO:0050710//negative regulation of cytokine secretion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0031953//negative regulation of protein autophosphorylation;GO:0009968//negative regulation of signal transduction;GO:0050728//negative regulation of inflammatory response;GO:0045381//regulation of interleukin-18 biosynthetic process;GO:0043122//regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050729//positive regulation of inflammatory response;GO:0007165//signal transduction;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0071345//cellular response to cytokine stimulus;GO:0008588//release of cytoplasmic sequestered NF-kappaB,GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process,K12800//Pertussis;Influenza A;NOD-like receptor signaling pathway
91663,0,55,0,0,0,6,0,7,8,0,0,0,MYADM;myeloid-associated differentiation marker,GO:0030864//cortical actin cytoskeleton;GO:0005911//cell-cell junction;GO:0016021//integral component of membrane;GO:0001726//ruffle;GO:0045121//membrane raft;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0061028//establishment of endothelial barrier;GO:0010629//negative regulation of gene expression;GO:0072661//protein targeting to plasma membrane;GO:0090038//negative regulation of protein kinase C signaling;GO:0030837//negative regulation of actin filament polymerization;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0031579//membrane raft organization;GO:0001933//negative regulation of protein phosphorylation;GO:0010810//regulation of cell-substrate adhesion;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0030335//positive regulation of cell migration;GO:0045217//cell-cell junction maintenance,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
91664,0,17,0,31,13,15,18,0,21,0,13,0,ZNF845;zinc finger protein 845,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9167,123,81,1,31,165,0,0,0,1,0,1,0,COX7A2L;cytochrome c oxidase subunit VIIa polypeptide 2 like,GO:0005743//mitochondrial inner membrane;GO:0005746//mitochondrial respiratory chain,GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain;GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process,GO:0004129//cytochrome-c oxidase activity,K02270//Cardiac muscle contraction;Huntington's disease;Parkinson's disease;Alzheimer's disease;Oxidative phosphorylation
9168,0,53,0,9,31,0,0,0,0,68,0,0,TMSB10;thymosin beta 10,GO:0005856//cytoskeleton;GO:0005737//cytoplasm,GO:0042989//sequestering of actin monomers;GO:0030036//actin cytoskeleton organization,GO:0003779//actin binding,-
91683,54,0,0,0,0,17,52,0,5,0,18,0,SYT12;synaptotagmin XII,GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane;GO:0016021//integral component of membrane,-,-,K15290//Synaptic vesicle cycle
91687,93,3,83,0,0,0,7,0,55,0,0,147,CENPL;centromere protein L,"GO:0005634//nucleus;GO:0000775//chromosome, centromeric region;GO:0005829//cytosol",GO:0000278//mitotic cell cycle,-,-
91689,81,0,1,1,12,0,0,0,8,0,1,0,SMDT1;single-pass membrane protein with aspartate-rich tail 1,GO:0031305//integral component of mitochondrial inner membrane;GO:1990246//uniplex complex,GO:0006851//mitochondrial calcium ion transport;GO:0051560//mitochondrial calcium ion homeostasis,-,-
9169,0,45,0,114,197,29,26,0,77,0,0,0,SCAF11;SR-related CTD-associated factor 11,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0000375//RNA splicing, via transesterification reactions;GO:0000245//spliceosomal complex assembly;GO:0008380//RNA splicing;GO:0006397//mRNA processing",GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
91694,1,25,19,7,68,0,0,189,18,0,0,0,LONRF1;LON peptidase N-terminal domain and ring finger 1,-,GO:0006508//proteolysis;GO:0006200//ATP catabolic process,GO:0008270//zinc ion binding;GO:0004176//ATP-dependent peptidase activity,-
91695,0,83,36,26,162,0,17,0,0,0,186,0,RRP7B;ribosomal RNA processing 7 homolog B (S. cerevisiae),-,-,-,K14545//Ribosome biogenesis in eukaryotes
917,0,0,0,0,0,1,35,0,2,0,0,216,"CD3G;CD3g molecule, gamma (CD3-TCR complex)",GO:0042105//alpha-beta T cell receptor complex;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0042101//T cell receptor complex,GO:0006461//protein complex assembly;GO:0045087//innate immune response;GO:0050776//regulation of immune response;GO:0031295//T cell costimulation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0007166//cell surface receptor signaling pathway;GO:0070228//regulation of lymphocyte apoptotic process;GO:0042110//T cell activation;GO:0050852//T cell receptor signaling pathway;GO:0007163//establishment or maintenance of cell polarity;GO:0015031//protein transport,GO:0042608//T cell receptor binding;GO:0004888//transmembrane signaling receptor activity;GO:0046982//protein heterodimerization activity;GO:0030159//receptor signaling complex scaffold activity,K06452//Measles;T cell receptor signaling pathway;Chagas disease (American trypanosomiasis);Hematopoietic cell lineage;HTLV-I infection
9170,0,0,0,0,7,0,0,0,0,0,0,0,LPAR2;lysophosphatidic acid receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0030139//endocytic vesicle,GO:0035025//positive regulation of Rho protein signal transduction;GO:0000187//activation of MAPK activity;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity,GO:0004930//G-protein coupled receptor activity;GO:0008289//lipid binding;GO:0030165//PDZ domain binding;GO:0070915//lysophosphatidic acid receptor activity;GO:0005515//protein binding,K04291//Neuroactive ligand-receptor interaction
91703,99,0,0,0,0,0,18,0,14,0,0,0,ACY3;aspartoacylase (aminocyclase) 3,GO:0070062//extracellular vesicular exosome;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm,GO:0016032//viral process;GO:0008152//metabolic process,"GO:0004046//aminoacylase activity;GO:0016788//hydrolase activity, acting on ester bonds;GO:0042802//identical protein binding;GO:0046872//metal ion binding","K01437//Histidine metabolism;Alanine, aspartate and glutamate metabolism"
9172,108,0,0,0,20,0,19,0,123,0,7,0,MYOM2;myomesin 2,GO:0005739//mitochondrion;GO:0032982//myosin filament;GO:0031430//M band,GO:0006936//muscle contraction,GO:0008307//structural constituent of muscle;GO:0005515//protein binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
9173,0,0,0,0,0,10,13,0,17,0,0,0,IL1RL1;interleukin 1 receptor-like 1,GO:0031012//extracellular matrix;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0035556//intracellular signal transduction;GO:0006955//immune response;GO:0050729//positive regulation of inflammatory response;GO:0007165//signal transduction;GO:0002826//negative regulation of T-helper 1 type immune response;GO:0043032//positive regulation of macrophage activation;GO:0032689//negative regulation of interferon-gamma production;GO:0032754//positive regulation of interleukin-5 production;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038172//interleukin-33-mediated signaling pathway;GO:0090197//positive regulation of chemokine secretion,GO:0004908//interleukin-1 receptor activity;GO:0004896//cytokine receptor activity;GO:0002114//interleukin-33 receptor activity;GO:0002113//interleukin-33 binding;GO:0005057//receptor signaling protein activity;GO:0005515//protein binding,-
91734,1,39,12,62,25,0,35,0,43,0,38,0,IDI2;isopentenyl-diphosphate delta isomerase 2,GO:0005777//peroxisome;GO:0005829//cytosol,GO:0008299//isoprenoid biosynthetic process;GO:0006695//cholesterol biosynthetic process;GO:0044281//small molecule metabolic process;GO:0046490//isopentenyl diphosphate metabolic process;GO:0050992//dimethylallyl diphosphate biosynthetic process,GO:0016787//hydrolase activity;GO:0004452//isopentenyl-diphosphate delta-isomerase activity;GO:0046872//metal ion binding,K01823//Biosynthesis of secondary metabolites;Metabolic pathways;Terpenoid backbone biosynthesis
91746,89,10,1,78,112,12,52,35,37,2,0,1,YTHDC1;YTH domain containing 1,GO:0005634//nucleus,GO:0006376//mRNA splice site selection,GO:0003723//RNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K12850//Spliceosome
91748,0,29,0,11,27,0,0,0,65,0,13,0,ELMSAN1;ELM2 and Myb/SANT-like domain containing 1,GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding,K11447//Transcriptional misregulation in cancer;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
91749,6,0,0,0,0,25,0,0,15,0,2,0,KIAA1919;KIAA1919,GO:0016324//apical plasma membrane;GO:0016021//integral component of membrane,GO:0008643//carbohydrate transport;GO:0006814//sodium ion transport;GO:0055085//transmembrane transport,GO:0015293//symporter activity,-
9175,0,17,0,69,220,11,40,26,80,2,102,0,MAP3K13;mitogen-activated protein kinase kinase kinase 13,GO:0008385//IkappaB kinase complex;GO:0016020//membrane,GO:0000186//activation of MAPKK activity;GO:0006468//protein phosphorylation;GO:0007254//JNK cascade;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0046777//protein autophosphorylation,GO:0005524//ATP binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0004709//MAP kinase kinase kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K04422//MAPK signaling pathway;K11447//Transcriptional misregulation in cancer
91750,0,27,0,0,8,0,0,0,2,0,0,0,LIN52;lin-52 homolog (C. elegans),GO:0005654//nucleoplasm;GO:0070176//DRM complex,"GO:0006351//transcription, DNA-templated;GO:0000278//mitotic cell cycle;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle",-,K00710//Mucin type O-Glycan biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
91752,24,0,0,0,0,12,14,0,42,0,12,0,ZNF804A;zinc finger protein 804A,-,-,GO:0046872//metal ion binding,-
91754,0,0,0,43,76,10,12,2,60,0,29,0,NEK9;NIMA-related kinase 9,GO:0005634//nucleus;GO:0005829//cytosol,GO:0007077//mitotic nuclear envelope disassembly;GO:0006468//protein phosphorylation;GO:0007067//mitotic nuclear division;GO:0000278//mitotic cell cycle,GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019901//protein kinase binding;GO:0005524//ATP binding,-
91768,0,0,0,9,35,0,61,28,12,0,0,215,CABLES1;Cdk5 and Abl enzyme substrate 1,GO:0005829//cytosol;GO:0005634//nucleus,GO:0045859//regulation of protein kinase activity;GO:0051726//regulation of cell cycle;GO:0007399//nervous system development;GO:0007049//cell cycle;GO:0051301//cell division;GO:0007596//blood coagulation;GO:0051302//regulation of cell division,GO:0016538//cyclin-dependent protein serine/threonine kinase regulator activity;GO:0005515//protein binding,-
9177,0,0,0,0,0,0,0,0,29,0,0,0,"HTR3B;5-hydroxytryptamine (serotonin) receptor 3B, ionotropic",GO:0045211//postsynaptic membrane;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007210//serotonin receptor signaling pathway;GO:0034220//ion transmembrane transport;GO:0006810//transport;GO:0007268//synaptic transmission;GO:0055085//transmembrane transport,GO:0005216//ion channel activity;GO:0004993//serotonin receptor activity;GO:0005232//serotonin-activated cation-selective channel activity,K04819//Serotonergic synapse
91775,88,32,0,0,21,0,0,0,104,1,0,0,"NXPE3;neurexophilin and PC-esterase domain family, member 3",GO:0005576//extracellular region,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
91782,0,0,0,5,40,0,34,0,38,0,4,0,CHMP7;charged multivesicular body protein 7,GO:0000815//ESCRT III complex;GO:0005829//cytosol,GO:0016032//viral process;GO:0015031//protein transport;GO:0016197//endosomal transport;GO:0061024//membrane organization;GO:0045324//late endosome to vacuole transport;GO:0019058//viral life cycle,GO:0008565//protein transporter activity,K15053//Endocytosis
9179,190,0,0,7,0,0,0,0,45,1,0,0,"AP4M1;adaptor-related protein complex 4, mu 1 subunit",GO:0030119//AP-type membrane coat adaptor complex;GO:0005905//coated pit;GO:0000138//Golgi trans cisterna;GO:0030131//clathrin adaptor complex;GO:0005802//trans-Golgi network;GO:0070062//extracellular vesicular exosome,GO:0016192//vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0006895//Golgi to endosome transport,GO:0005215//transporter activity,K12402//Lysosome
9180,0,0,0,7,0,2,72,0,39,0,0,0,OSMR;oncostatin M receptor,GO:0005900//oncostatin-M receptor complex,GO:0038165//oncostatin-M-mediated signaling pathway;GO:0002675//positive regulation of acute inflammatory response;GO:0007166//cell surface receptor signaling pathway;GO:0034097//response to cytokine;GO:0008283//cell proliferation;GO:0008284//positive regulation of cell proliferation,GO:0004924//oncostatin-M receptor activity;GO:0019838//growth factor binding,K05057//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
91807,0,0,0,0,0,27,52,0,19,0,0,0,MYLK3;myosin light chain kinase 3,GO:0005737//cytoplasm;GO:0015629//actin cytoskeleton;GO:0005829//cytosol,GO:0045214//sarcomere organization;GO:0071347//cellular response to interleukin-1;GO:0048769//sarcomerogenesis;GO:0002528//regulation of vascular permeability involved in acute inflammatory response;GO:0006468//protein phosphorylation;GO:0060298//positive regulation of sarcomere organization;GO:0055003//cardiac myofibril assembly,GO:0004683//calmodulin-dependent protein kinase activity;GO:0005524//ATP binding;GO:0004687//myosin light chain kinase activity,K00907//Gastric acid secretion;Calcium signaling pathway;Focal adhesion;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
9181,0,0,0,0,0,34,13,0,44,0,0,0,ARHGEF2;Rho/Rac guanine nucleotide exchange factor (GEF) 2,GO:0043234//protein complex;GO:0005819//spindle;GO:0005856//cytoskeleton;GO:0043025//neuronal cell body;GO:0031982//vesicle;GO:0005737//cytoplasm;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0043198//dendritic shaft;GO:0005794//Golgi apparatus;GO:0005874//microtubule;GO:0005829//cytosol;GO:0032587//ruffle membrane;GO:0005925//focal adhesion;GO:0005923//tight junction,GO:0071474//cellular hyperosmotic response;GO:0035023//regulation of Rho protein signal transduction;GO:0071225//cellular response to muramyl dipeptide;GO:0007067//mitotic nuclear division;GO:0006886//intracellular protein transport;GO:0071356//cellular response to tumor necrosis factor;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032755//positive regulation of interleukin-6 production;GO:0032321//positive regulation of Rho GTPase activity;GO:0060546//negative regulation of necroptotic process;GO:0042127//regulation of cell proliferation;GO:1902219//negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0007015//actin filament organization;GO:0007026//negative regulation of microtubule depolymerization;GO:0000902//cell morphogenesis;GO:0000132//establishment of mitotic spindle orientation;GO:0050768//negative regulation of neurogenesis;GO:0032760//positive regulation of tumor necrosis factor production;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045087//innate immune response;GO:0051056//regulation of small GTPase mediated signal transduction;GO:1902042//negative regulation of extrinsic apoptotic signaling pathway via death domain receptors;GO:0032855//positive regulation of Rac GTPase activity,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0008017//microtubule binding;GO:0017048//Rho GTPase binding;GO:0048365//Rac GTPase binding;GO:0008134//transcription factor binding;GO:0008270//zinc ion binding;GO:0005515//protein binding,K12791//Pathogenic Escherichia coli infection
9182,0,0,0,0,0,6,0,0,0,0,0,0,RASSF9;Ras association (RalGDS/AF-6) domain family (N-terminal) member 9,GO:0012510//trans-Golgi network transport vesicle membrane;GO:0005768//endosome;GO:0005829//cytosol,GO:0007165//signal transduction;GO:0006605//protein targeting;GO:0016197//endosomal transport,GO:0005215//transporter activity;GO:0005515//protein binding,-
91828,0,0,0,0,0,15,0,70,52,0,0,0,EXOC3L4;exocyst complex component 3-like 4,GO:0000145//exocyst,GO:0006887//exocytosis,-,K06110//Tight junction
9183,0,0,0,0,1,36,51,0,48,0,3,0,ZW10;zw10 kinetochore protein,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0000922//spindle pole;GO:0000776//kinetochore;GO:0005828//kinetochore microtubule;GO:0000777//condensed chromosome kinetochore;GO:0016020//membrane;GO:0005783//endoplasmic reticulum;GO:0005737//cytoplasm,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0007093//mitotic cell cycle checkpoint;GO:0006461//protein complex assembly;GO:0000278//mitotic cell cycle;GO:0034501//protein localization to kinetochore;GO:0007096//regulation of exit from mitosis;GO:0015031//protein transport;GO:0007080//mitotic metaphase plate congression;GO:0007126//meiotic nuclear division;GO:0000070//mitotic sister chromatid segregation;GO:0000132//establishment of mitotic spindle orientation,GO:0019237//centromeric DNA binding;GO:0005515//protein binding,-
91833,0,19,31,14,28,0,35,46,29,0,0,16,WDR20;WD repeat domain 20,-,-,-,K03130//Herpes simplex infection;Basal transcription factors;K12602//RNA degradation
9184,0,1,0,7,67,0,0,0,38,0,0,0,BUB3;BUB3 mitotic checkpoint protein,GO:0005829//cytosol;GO:0000777//condensed chromosome kinetochore;GO:0000776//kinetochore;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0000070//mitotic sister chromatid segregation;GO:0007126//meiotic nuclear division;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0051983//regulation of chromosome segregation;GO:0071173//spindle assembly checkpoint;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0008608//attachment of spindle microtubules to kinetochore,GO:0005515//protein binding,K02180//Cell cycle;Cell cycle - yeast;HTLV-I infection
9185,0,1,0,27,80,0,41,0,50,0,0,0,REPS2;RALBP1 associated Eps domain containing 2,GO:0005737//cytoplasm,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0006461//protein complex assembly,GO:0005515//protein binding;GO:0005509//calcium ion binding,K11447//Transcriptional misregulation in cancer;K14209//Protein digestion and absorption;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
91851,0,0,0,0,0,11,41,0,52,0,2,0,CHRDL1;chordin-like 1,GO:0005576//extracellular region,GO:0030514//negative regulation of BMP signaling pathway;GO:0030509//BMP signaling pathway;GO:0007399//nervous system development;GO:0048749//compound eye development;GO:0001654//eye development;GO:0001503//ossification;GO:0030154//cell differentiation,-,K04657//TGF-beta signaling pathway
91860,0,82,0,111,89,19,0,148,11,0,87,0,CALML4;calmodulin-like 4,-,-,GO:0005509//calcium ion binding,K02183//Glioma;Gastric acid secretion;Melanogenesis;Neurotrophin signaling pathway;Alzheimer's disease;Olfactory transduction;Calcium signaling pathway;Salivary secretion;Phototransduction - fly;Plant-pathogen interaction;Amphetamine addiction;Vascular smooth muscle contraction;Oocyte meiosis;Alcoholism;Tuberculosis;Pertussis;Long-term potentiation;Phosphatidylinositol signaling system;GnRH signaling pathway;Dopaminergic synapse;Insulin signaling pathway;Phototransduction
91862,0,0,0,0,27,0,0,3,46,0,0,0,MARVELD3;MARVEL domain containing 3,GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0031410//cytoplasmic vesicle,GO:0070830//tight junction assembly;GO:0045216//cell-cell junction organization,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
91869,0,0,0,0,0,0,94,0,9,0,1,0,RFT1;RFT1 homolog (S. cerevisiae),GO:0016021//integral component of membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0006869//lipid transport;GO:0008643//carbohydrate transport;GO:0043687//post-translational protein modification,GO:0005319//lipid transporter activity,K06316//N-Glycan biosynthesis
91875,0,0,0,6,29,0,0,0,23,0,0,0,TTC5;tetratricopeptide repeat domain 5,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005730//nucleolus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006281//DNA repair,GO:0003677//DNA binding;GO:0003682//chromatin binding,K09667//Other types of O-glycan biosynthesis
9188,0,47,0,69,98,15,51,0,11,70,0,0,DDX21;DEAD (Asp-Glu-Ala-Asp) box helicase 21,GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus,GO:0043330//response to exogenous dsRNA;GO:0001649//osteoblast differentiation;GO:0009615//response to virus;GO:0006200//ATP catabolic process,GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0003725//double-stranded RNA binding;GO:0005524//ATP binding,-
9189,0,0,0,0,0,3,0,4,0,0,0,0,"ZBED1;zinc finger, BED-type containing 1",GO:0000228//nuclear chromosome,GO:0008152//metabolic process,GO:0046983//protein dimerization activity;GO:0004803//transposase activity;GO:0003677//DNA binding;GO:0046872//metal ion binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
91893,0,27,40,39,40,21,0,0,22,0,34,0,FDXACB1;ferredoxin-fold anticodon binding domain containing 1,-,GO:0008033//tRNA processing;GO:0006432//phenylalanyl-tRNA aminoacylation,GO:0004826//phenylalanine-tRNA ligase activity;GO:0000287//magnesium ion binding;GO:0000049//tRNA binding;GO:0005524//ATP binding,K03846//Metabolic pathways;Various types of N-glycan biosynthesis;N-Glycan biosynthesis
919,41,0,0,0,0,21,4,0,5,0,0,0,CD247;CD247 molecule,GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0042101//T cell receptor complex;GO:0042105//alpha-beta T cell receptor complex;GO:0005737//cytoplasm,GO:0016032//viral process;GO:0045087//innate immune response;GO:0031295//T cell costimulation;GO:0050776//regulation of immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0050852//T cell receptor signaling pathway;GO:0050690//regulation of defense response to virus by virus,GO:0042802//identical protein binding;GO:0042803//protein homodimerization activity;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding,K06453//T cell receptor signaling pathway;Natural killer cell mediated cytotoxicity;Chagas disease (American trypanosomiasis)
9191,0,68,11,19,62,19,0,0,0,0,20,0,DEDD;death effector domain containing,GO:0005730//nucleolus;GO:0005737//cytoplasm,"GO:0007283//spermatogenesis;GO:1901837//negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0046697//decidualization;GO:0042177//negative regulation of protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0006351//transcription, DNA-templated",GO:0005515//protein binding;GO:0003677//DNA binding,-
91937,163,0,0,0,0,9,9,1,12,0,0,0,TIMD4;T-cell immunoglobulin and mucin domain containing 4,GO:0016021//integral component of membrane,-,-,-
9194,36,0,0,0,0,23,19,0,70,288,0,0,"SLC16A7;solute carrier family 16 (monocarboxylate transporter), member 7",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:1901475//pyruvate transmembrane transport;GO:0035873//lactate transmembrane transport;GO:0055085//transmembrane transport,GO:0005477//pyruvate secondary active transmembrane transporter activity;GO:0050833//pyruvate transmembrane transporter activity;GO:0015355//secondary active monocarboxylate transmembrane transporter activity;GO:0015129//lactate transmembrane transporter activity;GO:0015293//symporter activity,-
91942,0,0,0,0,0,0,0,0,7,0,0,0,"NDUFAF2;NADH dehydrogenase (ubiquinone) complex I, assembly factor 2",GO:0005739//mitochondrion,GO:0072593//reactive oxygen species metabolic process;GO:0061179//negative regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0022904//respiratory electron transport chain,GO:0008137//NADH dehydrogenase (ubiquinone) activity,K11352//Metabolic pathways;Parkinson's disease;Huntington's disease;Oxidative phosphorylation;Alzheimer's disease
91947,0,0,0,18,29,0,0,0,38,0,0,0,ARRDC4;arrestin domain containing 4,GO:0005886//plasma membrane;GO:0005768//endosome,GO:0051443//positive regulation of ubiquitin-protein transferase activity,-,-
91949,83,0,4,16,4,0,0,1,34,0,16,0,COG7;component of oligomeric golgi complex 7,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0017119//Golgi transport complex,"GO:0033365//protein localization to organelle;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport;GO:0050821//protein stabilization;GO:0006486//protein glycosylation;GO:0034067//protein localization to Golgi apparatus",GO:0005515//protein binding,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways
9196,0,0,0,0,1,0,0,0,30,17,1,0,"KCNAB3;potassium voltage-gated channel, shaker-related subfamily, beta member 3",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0006813//potassium ion transport;GO:0071805//potassium ion transmembrane transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport,GO:0015459//potassium channel regulator activity;GO:0005249//voltage-gated potassium channel activity,-
91966,58,1,0,1,39,0,12,0,23,0,17,693,CXorf40A;chromosome X open reading frame 40A,-,-,GO:0005515//protein binding,-
9197,0,0,0,3,26,0,23,0,24,0,8,0,"SLC33A1;solute carrier family 33 (acetyl-CoA transporter), member 1",GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005887//integral component of plasma membrane,GO:0015876//acetyl-CoA transport;GO:0055085//transmembrane transport;GO:0008219//cell death;GO:0006810//transport,GO:0008521//acetyl-CoA transporter activity,K03372//Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series
91975,0,0,0,0,19,0,2,0,10,0,0,0,ZNF300;zinc finger protein 300,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
91977,0,0,0,0,0,0,0,0,2,1,14,0,MYOZ3;myozenin 3,GO:0030018//Z disc,-,GO:0005515//protein binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
91978,0,0,0,0,0,7,0,1,0,0,0,0,TPGS1;tubulin polyglutamylase complex subunit 1,GO:0005874//microtubule;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0030424//axon;GO:0030425//dendrite;GO:0031514//motile cilium,GO:0030534//adult behavior;GO:0018095//protein polyglutamylation;GO:0007275//multicellular organismal development;GO:0007288//sperm axoneme assembly;GO:0051648//vesicle localization;GO:0007268//synaptic transmission,GO:0008017//microtubule binding;GO:0070740//tubulin-glutamic acid ligase activity,K02207//Ubiquitin mediated proteolysis;Herpes simplex infection
92,0,0,27,31,119,16,0,0,44,0,0,0,"ACVR2A;activin A receptor, type IIA",GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0034673//inhibin-betaglycan-ActRII complex;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,GO:0050999//regulation of nitric-oxide synthase activity;GO:0007283//spermatogenesis;GO:0001934//positive regulation of protein phosphorylation;GO:0006468//protein phosphorylation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0048706//embryonic skeletal system development;GO:0009952//anterior/posterior pattern specification;GO:0043084//penile erection;GO:0001702//gastrulation with mouth forming second;GO:0007368//determination of left/right symmetry;GO:0023014//signal transduction by phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0045648//positive regulation of erythrocyte differentiation;GO:0007498//mesoderm development;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0042713//sperm ejaculation;GO:0030509//BMP signaling pathway;GO:0030510//regulation of BMP signaling pathway;GO:0060011//Sertoli cell proliferation;GO:0032924//activin receptor signaling pathway;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0071773//cellular response to BMP stimulus;GO:0045669//positive regulation of osteoblast differentiation,GO:0019838//growth factor binding;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0015026//coreceptor activity;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0048185//activin binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0043621//protein self-association;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0005524//ATP binding;GO:0034711//inhibin binding,K04670//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
920,0,0,56,9,33,0,0,0,5,0,8,0,CD4;CD4 molecule,GO:0005789//endoplasmic reticulum membrane;GO:0005788//endoplasmic reticulum lumen;GO:0042101//T cell receptor complex;GO:0016021//integral component of membrane;GO:0045121//membrane raft;GO:0005769//early endosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0050863//regulation of T cell activation;GO:0030260//entry into host cell;GO:0045860//positive regulation of protein kinase activity;GO:0007165//signal transduction;GO:0016032//viral process;GO:0050850//positive regulation of calcium-mediated signaling;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0007155//cell adhesion;GO:0006948//induction by virus of host cell-cell fusion;GO:0001816//cytokine production;GO:0050690//regulation of defense response to virus by virus;GO:0050852//T cell receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0007166//cell surface receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0050829//defense response to Gram-negative bacterium;GO:0030217//T cell differentiation;GO:0045087//innate immune response;GO:0045234//protein palmitoleylation;GO:0031295//T cell costimulation;GO:0032507//maintenance of protein location in cell;GO:0006955//immune response;GO:0045058//T cell selection;GO:0007167//enzyme linked receptor protein signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0019901//protein kinase binding;GO:0004872//receptor activity;GO:0019899//enzyme binding;GO:0001948//glycoprotein binding;GO:0005515//protein binding;GO:0005201//extracellular matrix structural constituent;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding;GO:0015026//coreceptor activity;GO:0042289//MHC class II protein binding,K06454//Antigen processing and presentation;Hematopoietic cell lineage;Primary immunodeficiency;Cell adhesion molecules (CAMs);T cell receptor signaling pathway
9200,0,0,0,0,0,12,0,0,0,0,12,0,"PTPLA;protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0014902//myotube differentiation;GO:0007165//signal transduction;GO:0006633//fatty acid biosynthetic process;GO:0010389//regulation of G2/M transition of mitotic cell cycle;GO:2000045//regulation of G1/S transition of mitotic cell cycle;GO:0007275//multicellular organismal development;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0006470//protein dephosphorylation,GO:0016829//lyase activity;GO:0004725//protein tyrosine phosphatase activity,K10703//Biosynthesis of secondary metabolites;Biosynthesis of unsaturated fatty acids;Fatty acid elongation
92002,0,0,0,0,0,0,47,0,39,0,12,0,"FAM58A;family with sequence similarity 58, member A",-,"GO:0006355//regulation of transcription, DNA-templated;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity",GO:0005515//protein binding;GO:0019901//protein kinase binding,K15188//Transcriptional misregulation in cancer
9201,0,0,43,0,0,14,0,58,132,87,50,0,DCLK1;doublecortin-like kinase 1,GO:0005887//integral component of plasma membrane,GO:0035556//intracellular signal transduction;GO:0030900//forebrain development;GO:0021952//central nervous system projection neuron axonogenesis;GO:0009615//response to virus;GO:0016197//endosomal transport;GO:0007417//central nervous system development;GO:0006468//protein phosphorylation;GO:0007399//nervous system development;GO:0001764//neuron migration;GO:0048813//dendrite morphogenesis;GO:0048675//axon extension,GO:0005524//ATP binding;GO:0005057//receptor signaling protein activity;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity,-
92014,0,0,0,1,0,0,0,0,11,0,0,0,"SLC25A51;solute carrier family 25, member 51",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0006810//transport,-,K01587//Purine metabolism;Metabolic pathways
92017,2,0,0,1,7,29,20,64,65,0,1,0,SNX29;sorting nexin 29,GO:0070062//extracellular vesicular exosome,-,GO:0035091//phosphatidylinositol binding,-
9202,0,29,2,37,261,0,37,0,73,0,15,0,"ZMYM4;zinc finger, MYM-type 4",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0022604//regulation of cell morphogenesis;GO:0007010//cytoskeleton organization;GO:0007275//multicellular organismal development,GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
9203,51,12,0,0,21,9,16,0,17,0,21,0,"ZMYM3;zinc finger, MYM-type 3",GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0007010//cytoskeleton organization;GO:0022604//regulation of cell morphogenesis,GO:0008270//zinc ion binding;GO:0003677//DNA binding,-
9204,0,0,0,5,15,0,38,0,10,0,0,0,"ZMYM6;zinc finger, MYM-type 6",GO:0005634//nucleus,GO:0007010//cytoskeleton organization;GO:0007275//multicellular organismal development;GO:0022604//regulation of cell morphogenesis,GO:0008270//zinc ion binding;GO:0003677//DNA binding,K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
9205,0,0,1,0,0,0,15,0,1,0,0,0,"ZMYM5;zinc finger, MYM-type 5",GO:0005634//nucleus,-,GO:0008270//zinc ion binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
92070,0,0,0,0,0,0,0,0,21,0,0,0,CTBP1-AS2;CTBP1 antisense RNA 2 (head to head),-,-,-,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K01539//Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion
9208,0,30,0,57,199,44,32,49,59,0,5,0,LRRFIP1;leucine rich repeat (in FLII) interacting protein 1,GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005829//cytosol,"GO:0045087//innate immune response;GO:0032481//positive regulation of type I interferon production;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006357//regulation of transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0003725//double-stranded RNA binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding,K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K04514//Regulation of actin cytoskeleton;Wnt signaling pathway;Vascular smooth muscle contraction;Focal adhesion;Pathogenic Escherichia coli infection;Salmonella infection;Chemokine signaling pathway;Axon guidance;Leukocyte transendothelial migration;Shigellosis;TGF-beta signaling pathway;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption
92086,0,0,0,0,0,0,0,1,17,0,0,0,GGTLC1;gamma-glutamyltransferase light chain 1,GO:0031362//anchored component of external side of plasma membrane,GO:0006749//glutathione metabolic process;GO:0019370//leukotriene biosynthetic process,GO:0003840//gamma-glutamyltransferase activity,K00681//Cyanoamino acid metabolism;Glutathione metabolism;Taurine and hypotaurine metabolism;Metabolic pathways;Arachidonic acid metabolism
9209,87,39,1,21,137,0,46,0,54,0,0,0,LRRFIP2;leucine rich repeat (in FLII) interacting protein 2,-,GO:0016055//Wnt signaling pathway,GO:0030275//LRR domain binding;GO:0005515//protein binding,K10352//Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction
92092,0,0,0,24,1,0,7,0,32,0,62,0,"ZC3HAV1L;zinc finger CCCH-type, antiviral 1-like",-,-,-,-
921,59,0,0,0,0,17,3,3,26,0,37,0,CD5;CD5 molecule,GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane,GO:0006898//receptor-mediated endocytosis;GO:0008283//cell proliferation;GO:0008037//cell recognition;GO:0031295//T cell costimulation;GO:0097190//apoptotic signaling pathway,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0004872//receptor activity;GO:0005044//scavenger receptor activity,K06455//Hematopoietic cell lineage
9210,0,0,0,0,0,0,22,0,9,0,0,0,BMP15;bone morphogenetic protein 15,GO:0005737//cytoplasm;GO:0005615//extracellular space,"GO:0060016//granulosa cell development;GO:0007292//female gamete generation;GO:0001541//ovarian follicle development;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008083//growth factor activity;GO:0005125//cytokine activity,-
92104,0,1,0,3,1,31,0,5,3,0,13,0,TTC30A;tetratricopeptide repeat domain 30A,GO:0030992//intraciliary transport particle B;GO:0005929//cilium,GO:0042384//cilium assembly;GO:0042073//intraciliary transport,-,-
92105,0,1,2,5,13,0,36,0,58,0,18,0,INTS4;integrator complex subunit 4,GO:0032039//integrator complex,GO:0016180//snRNA processing,GO:0005515//protein binding,-
92106,0,0,1,1,14,10,28,0,15,0,0,295,OXNAD1;oxidoreductase NAD-binding domain containing 1,GO:0005739//mitochondrion,GO:0055114//oxidation-reduction process,GO:0016491//oxidoreductase activity,K00326//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism
9211,0,0,0,0,0,0,0,0,20,141,0,0,"LGI1;leucine-rich, glioma inactivated 1",GO:0030054//cell junction;GO:0045202//synapse;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0050806//positive regulation of synaptic transmission;GO:0030307//positive regulation of cell growth;GO:0008283//cell proliferation;GO:0051260//protein homooligomerization;GO:0031175//neuron projection development;GO:0007411//axon guidance;GO:0007399//nervous system development,GO:0005102//receptor binding;GO:0005515//protein binding,K06839//Axon guidance
9212,0,0,0,0,0,0,0,51,25,0,2,0,AURKB;aurora kinase B,"GO:0000779//condensed chromosome, centromeric region;GO:0010369//chromocenter;GO:0005819//spindle;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0045171//intercellular bridge;GO:0000780//condensed nuclear chromosome, centromeric region;GO:0030496//midbody;GO:0005634//nucleus;GO:0032133//chromosome passenger complex",GO:0002903//negative regulation of B cell apoptotic process;GO:0043146//spindle stabilization;GO:0031577//spindle checkpoint;GO:0046777//protein autophosphorylation;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007568//aging;GO:0016570//histone modification;GO:0032467//positive regulation of cytokinesis;GO:0006468//protein phosphorylation;GO:0036089//cleavage furrow formation;GO:0000278//mitotic cell cycle;GO:0008608//attachment of spindle microtubules to kinetochore;GO:0009838//abscission;GO:0051983//regulation of chromosome segregation;GO:0032091//negative regulation of protein binding;GO:0032466//negative regulation of cytokinesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0034501//protein localization to kinetochore;GO:0043988//histone H3-S28 phosphorylation;GO:0034644//cellular response to UV;GO:0008283//cell proliferation;GO:0051256//spindle midzone assembly involved in mitosis;GO:0031565//cytokinesis checkpoint,GO:0005524//ATP binding;GO:0035174//histone serine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0005515//protein binding,-
92126,0,0,0,10,7,0,50,65,40,0,14,1,DSEL;dermatan sulfate epimerase-like,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0030208//dermatan sulfate biosynthetic process;GO:0030204//chondroitin sulfate metabolic process;GO:0005975//carbohydrate metabolic process,GO:0008146//sulfotransferase activity;GO:0016853//isomerase activity,K01794//Glycosaminoglycan biosynthesis - chondroitin sulfate
92129,0,0,0,0,8,0,0,0,0,0,0,0,RIPPLY1;ripply transcriptional repressor 1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060349//bone morphogenesis;GO:0032525//somite rostral/caudal axis specification;GO:0001757//somite specification;GO:0007219//Notch signaling pathway;GO:0009880//embryonic pattern specification",-,-
9213,185,47,0,0,1,29,36,32,77,1,0,0,XPR1;xenotropic and polytropic retrovirus receptor 1,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0009615//response to virus;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004888//transmembrane signaling receptor activity;GO:0001618//virus receptor activity;GO:0004930//G-protein coupled receptor activity;GO:0004872//receptor activity,K11447//Transcriptional misregulation in cancer;K14443//RNA degradation;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
9214,0,0,0,0,0,17,10,54,83,0,0,0,FAIM3;Fas apoptotic inhibitory molecule 3,GO:0005576//extracellular region;GO:0016021//integral component of membrane,GO:0006968//cellular defense response;GO:0002376//immune system process;GO:0043066//negative regulation of apoptotic process,-,K13073//Intestinal immune network for IgA production
92140,8,1,0,13,26,13,0,0,63,0,7,0,MTDH;metadherin,GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0031965//nuclear membrane;GO:0016604//nuclear body;GO:0005730//nucleolus;GO:0005923//tight junction;GO:0046581//intercellular canaliculus;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane,GO:0043066//negative regulation of apoptotic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045766//positive regulation of angiogenesis;GO:0051897//positive regulation of protein kinase B signaling;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0070830//tight junction assembly;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0010508//positive regulation of autophagy,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0003725//double-stranded RNA binding;GO:0003713//transcription coactivator activity;GO:0051059//NF-kappaB binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
9215,0,0,0,0,0,23,0,0,36,0,0,0,LARGE;like-glycosyltransferase,GO:0030173//integral component of Golgi membrane,GO:0009101//glycoprotein biosynthetic process;GO:0046716//muscle cell cellular homeostasis;GO:0006486//protein glycosylation;GO:0006688//glycosphingolipid biosynthetic process;GO:0006044//N-acetylglucosamine metabolic process,"GO:0016757//transferase activity, transferring glycosyl groups;GO:0008375//acetylglucosaminyltransferase activity",-
92154,13,6,0,0,16,0,15,0,0,0,0,0,MTSS1L;metastasis suppressor 1-like,-,GO:0046847//filopodium assembly;GO:0007165//signal transduction,GO:0008093//cytoskeletal adaptor activity;GO:0017124//SH3 domain binding;GO:0003779//actin binding,K05627//Regulation of actin cytoskeleton;Adherens junction
92162,0,0,0,0,0,0,0,0,14,0,0,0,TMEM88;transmembrane protein 88,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007275//multicellular organismal development;GO:0016055//Wnt signaling pathway,-,-
9217,0,16,0,55,132,18,0,0,14,0,12,0,VAPB;VAMP (vesicle-associated membrane protein)-associated protein B and C,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus;GO:0005789//endoplasmic reticulum membrane,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030148//sphingolipid biosynthetic process;GO:0044281//small molecule metabolic process;GO:0008219//cell death;GO:0045070//positive regulation of viral genome replication;GO:0006874//cellular calcium ion homeostasis;GO:0006665//sphingolipid metabolic process;GO:0019048//modulation by virus of host morphology or physiology;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0019899//enzyme binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005198//structural molecule activity;GO:0005515//protein binding;GO:0048487//beta-tubulin binding,-
92170,85,2,0,0,0,3,0,0,13,0,0,0,MTG1;mitochondrial ribosome-associated GTPase 1,GO:0005761//mitochondrial ribosome;GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0044065//regulation of respiratory system process;GO:0006184//GTP catabolic process;GO:0070129//regulation of mitochondrial translation;GO:0042254//ribosome biogenesis,GO:0003924//GTPase activity;GO:0005525//GTP binding,K14538//Ribosome biogenesis in eukaryotes
9218,2,7,0,113,211,0,54,61,43,0,0,1,"VAPA;VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa",GO:0048471//perinuclear region of cytoplasm;GO:0015630//microtubule cytoskeleton;GO:0005789//endoplasmic reticulum membrane;GO:0005923//tight junction;GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0031175//neuron projection development;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0030148//sphingolipid biosynthetic process;GO:0008219//cell death;GO:0070972//protein localization to endoplasmic reticulum;GO:0061025//membrane fusion;GO:0006665//sphingolipid metabolic process,GO:0004871//signal transducer activity;GO:0005198//structural molecule activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding,K06096//Tight junction
92181,0,29,0,35,25,33,0,0,2,0,1,1,UBTD2;ubiquitin domain containing 2,GO:0005737//cytoplasm,-,-,-
9219,98,37,1,15,50,0,9,0,65,0,0,0,"MTA2;metastasis associated 1 family, member 2",GO:0005667//transcription factor complex;GO:0005634//nucleus;GO:0000790//nuclear chromatin;GO:0016581//NuRD complex;GO:0005730//nucleolus;GO:0043234//protein complex;GO:0016020//membrane;GO:0000118//histone deacetylase complex,GO:0006306//DNA methylation;GO:0043044//ATP-dependent chromatin remodeling;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0016575//histone deacetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006333//chromatin assembly or disassembly,GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001085//RNA polymerase II transcription factor binding;GO:0004407//histone deacetylase activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0000989//transcription factor binding transcription factor activity;GO:0001103//RNA polymerase II repressing transcription factor binding;GO:0031492//nucleosomal DNA binding;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding,-
92196,0,0,0,0,14,0,0,0,15,0,0,0,DAPL1;death associated protein-like 1,-,GO:0030154//cell differentiation;GO:0006915//apoptotic process,-,-
922,0,0,0,0,0,44,0,0,24,0,0,0,CD5L;CD5 molecule-like,GO:0005615//extracellular space;GO:0016020//membrane;GO:0005576//extracellular region;GO:0072562//blood microparticle;GO:0070062//extracellular vesicular exosome,GO:0006915//apoptotic process;GO:0006898//receptor-mediated endocytosis;GO:0006968//cellular defense response,GO:0005044//scavenger receptor activity,K13912//Salivary secretion
9220,0,0,0,0,0,0,14,0,0,0,0,0,TIAF1;TGFB1-induced anti-apoptotic factor 1,GO:0005634//nucleus,GO:0043066//negative regulation of apoptotic process;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0006915//apoptotic process,-,-
9221,0,19,0,59,203,0,26,0,11,0,3,199,NOLC1;nucleolar and coiled-body phosphoprotein 1,GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005737//cytoplasm,GO:0007067//mitotic nuclear division;GO:0007049//cell cycle;GO:0006364//rRNA processing;GO:0007000//nucleolus organization,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0005525//GTP binding,-
92211,159,0,0,0,0,0,18,63,91,2,0,0,CDHR1;cadherin-related family member 1,GO:0005887//integral component of plasma membrane;GO:0042622//photoreceptor outer segment membrane,GO:0045494//photoreceptor cell maintenance;GO:0009987//cellular process;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
9223,3,17,0,55,115,0,68,0,59,0,18,0,"MAGI1;membrane associated guanylate kinase, WW and PDZ domain containing 1",GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005737//cytoplasm;GO:0005911//cell-cell junction;GO:0005730//nucleolus;GO:0005923//tight junction;GO:0042995//cell projection;GO:0005634//nucleus,GO:0006461//protein complex assembly;GO:0007166//cell surface receptor signaling pathway;GO:0007155//cell adhesion;GO:0070997//neuron death,GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0051393//alpha-actinin binding,K05631//Tight junction
92235,107,0,0,0,9,0,0,17,18,0,1,0,DUSP27;dual specificity phosphatase 27 (putative),-,GO:0006470//protein dephosphorylation,GO:0008138//protein tyrosine/serine/threonine phosphatase activity,-
92241,0,0,0,0,0,0,0,0,39,84,9,0,RCSD1;RCSD domain containing 1,GO:0005884//actin filament,GO:0071474//cellular hyperosmotic response;GO:0003009//skeletal muscle contraction,GO:0051015//actin filament binding,-
92249,0,0,0,0,21,0,0,0,8,0,0,0,LINC01278;long intergenic non-protein coding RNA 1278,-,-,-,K13962//Gastric acid secretion;K04257//Olfactory transduction
92255,0,0,0,4,16,26,16,0,21,0,12,0,LMBRD2;LMBR1 domain containing 2,GO:0016020//membrane;GO:0016021//integral component of membrane,-,-,-
92259,0,0,0,15,0,0,32,0,13,0,0,0,MRPS36;mitochondrial ribosomal protein S36,GO:0005763//mitochondrial small ribosomal subunit;GO:0005739//mitochondrion,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
9227,0,0,0,0,0,4,0,0,0,0,0,0,LRAT;lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase),GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0005771//multivesicular body;GO:0005791//rough endoplasmic reticulum;GO:0016021//integral component of membrane,"GO:0007601//visual perception;GO:0042573//retinoic acid metabolic process;GO:0006776//vitamin A metabolic process;GO:0001523//retinoid metabolic process;GO:0042572//retinol metabolic process;GO:0007603//phototransduction, visible light","GO:0016746//transferase activity, transferring acyl groups;GO:0001972//retinoic acid binding;GO:0047173//phosphatidylcholine-retinol O-acyltransferase activity;GO:0019841//retinol binding",K00678//Retinol metabolism;Vitamin digestion and absorption
92270,0,0,26,0,0,0,0,0,22,0,5,0,"ATP6AP1L;ATPase, H+ transporting, lysosomal accessory protein 1-like","GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0016021//integral component of membrane",GO:0015991//ATP hydrolysis coupled proton transport,"GO:0046933//proton-transporting ATP synthase activity, rotational mechanism;GO:0046961//proton-transporting ATPase activity, rotational mechanism",K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K03662//Tuberculosis;Phagosome;Rheumatoid arthritis;Lysosome;Vibrio cholerae infection;Epithelial cell signaling in Helicobacter pylori infection;Metabolic pathways;Oxidative phosphorylation;K11447//Transcriptional misregulation in cancer
9228,0,0,0,0,0,27,0,68,63,1,0,0,"DLGAP2;discs, large (Drosophila) homolog-associated protein 2",GO:0014069//postsynaptic density;GO:0045211//postsynaptic membrane;GO:0005883//neurofilament;GO:0030054//cell junction,GO:0007270//neuron-neuron synaptic transmission,GO:0005515//protein binding,K15008//Glutamatergic synapse
92283,232,0,0,0,0,0,0,0,25,0,0,0,ZNF461;zinc finger protein 461,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
92285,0,26,0,25,26,1,0,0,30,0,0,0,ZNF585B;zinc finger protein 585B,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003676//nucleic acid binding,-
9229,0,31,0,5,26,18,9,0,13,0,0,6,"DLGAP1;discs, large (Drosophila) homolog-associated protein 1",GO:0030054//cell junction;GO:0097481//neuronal postsynaptic density;GO:0045211//postsynaptic membrane,GO:0007268//synaptic transmission,GO:0005515//protein binding,K15008//Glutamatergic synapse
92291,178,0,0,0,0,0,0,32,40,0,0,0,CAPN13;calpain 13,GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0004198//calcium-dependent cysteine-type endopeptidase activity;GO:0005509//calcium ion binding,-
92292,0,26,0,17,24,14,53,0,0,0,0,1,GLYATL1;glycine-N-acyltransferase-like 1,GO:0005739//mitochondrion,GO:0008152//metabolic process,GO:0047961//glycine N-acyltransferase activity;GO:0047946//glutamine N-acyltransferase activity,K15517//Phenylalanine metabolism;K00628//Phenylalanine metabolism
92293,22,0,0,0,0,1,25,0,25,0,22,0,TMEM132C;transmembrane protein 132C,GO:0016021//integral component of membrane,-,-,-
923,0,0,0,0,0,0,20,50,27,94,2,0,CD6;CD6 molecule,GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:0006898//receptor-mediated endocytosis,GO:0005515//protein binding;GO:0005044//scavenger receptor activity,K06456//Cell adhesion molecules (CAMs)
9230,0,75,0,28,72,0,0,1,25,0,43,0,"RAB11B;RAB11B, member RAS oncogene family",GO:0055037//recycling endosome;GO:0055038//recycling endosome membrane;GO:0005739//mitochondrion;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0030672//synaptic vesicle membrane;GO:0045335//phagocytic vesicle;GO:0030054//cell junction;GO:0008021//synaptic vesicle,"GO:0035773//insulin secretion involved in cellular response to glucose stimulus;GO:0032402//melanosome transport;GO:0045054//constitutive secretory pathway;GO:0007264//small GTPase mediated signal transduction;GO:0033572//transferrin transport;GO:2000008//regulation of protein localization to cell surface;GO:2001135//regulation of endocytic recycling;GO:0045055//regulated secretory pathway;GO:1990126//retrograde transport, endosome to plasma membrane;GO:0044070//regulation of anion transport;GO:0001881//receptor recycling;GO:0006184//GTP catabolic process;GO:0071468//cellular response to acidic pH",GO:0019003//GDP binding;GO:0005515//protein binding;GO:0005525//GTP binding;GO:0003924//GTPase activity,K07905//Endocytosis;Vasopressin-regulated water reabsorption
92304,3,0,0,0,0,0,0,0,21,0,0,0,"SCGB3A1;secretoglobin, family 3A, member 1",GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,GO:0030308//negative regulation of cell growth;GO:0042127//regulation of cell proliferation,GO:0005125//cytokine activity,-
92305,0,4,1,0,0,24,0,1,21,0,24,0,TMEM129;transmembrane protein 129,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006986//response to unfolded protein;GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0046872//metal ion binding,-
9231,94,27,46,29,98,54,41,113,22,152,0,0,"DLG5;discs, large homolog 5 (Drosophila)",GO:0005913//cell-cell adherens junction;GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0045176//apical protein localization;GO:0030859//polarized epithelial cell differentiation;GO:0060441//epithelial tube branching involved in lung morphogenesis;GO:0030901//midbrain development;GO:0072205//metanephric collecting duct development;GO:0006461//protein complex assembly;GO:0042981//regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0071896//protein localization to adherens junction;GO:0035556//intracellular signal transduction;GO:0045197//establishment or maintenance of epithelial cell apical/basal polarity,GO:0008092//cytoskeletal protein binding;GO:0008013//beta-catenin binding;GO:0030159//receptor signaling complex scaffold activity;GO:0005515//protein binding,K12076//T cell receptor signaling pathway;HTLV-I infection
92312,0,0,0,6,1,1,14,42,19,0,13,0,MEX3A;mex-3 RNA binding family member A,GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus,-,GO:0044822//poly(A) RNA binding;GO:0008270//zinc ion binding,-
9232,0,0,0,0,0,26,10,0,0,0,12,0,PTTG1;pituitary tumor-transforming 1,GO:0005829//cytosol;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair;GO:0006355//regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:0051276//chromosome organization;GO:0010951//negative regulation of endopeptidase activity;GO:0007283//spermatogenesis;GO:0000278//mitotic cell cycle;GO:0007059//chromosome segregation",GO:0005515//protein binding;GO:0004869//cysteine-type endopeptidase inhibitor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0017124//SH3 domain binding,K06635//Cell cycle;Oocyte meiosis;HTLV-I infection
92335,0,0,1,0,48,5,0,0,10,0,14,604,STRADA;STE20-related kinase adaptor alpha,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007050//cell cycle arrest;GO:0006468//protein phosphorylation;GO:0032147//activation of protein kinase activity;GO:0008286//insulin receptor signaling pathway;GO:0006611//protein export from nucleus,GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0019900//kinase binding;GO:0030295//protein kinase activator activity;GO:0005524//ATP binding,K08271//mTOR signaling pathway
92340,0,0,0,0,0,0,20,0,44,0,5,0,PRR29;proline rich 29,-,-,-,K06523//Natural killer cell mediated cytotoxicity;Cell adhesion molecules (CAMs)
92342,0,0,0,0,12,0,0,0,42,0,0,0,METTL18;methyltransferase like 18,GO:0005737//cytoplasm,GO:0006479//protein methylation,GO:0008276//protein methyltransferase activity,-
92344,0,0,0,0,9,0,20,0,42,0,0,0,"GORAB;golgin, RAB6-interacting",GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,-,GO:0005515//protein binding,-
92345,0,0,17,0,0,0,5,0,28,0,0,0,NAF1;nuclear assembly factor 1 ribonucleoprotein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005732//small nucleolar ribonucleoprotein complex,GO:0001522//pseudouridine synthesis;GO:0006364//rRNA processing;GO:0042254//ribosome biogenesis,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003723//RNA binding,-
92346,0,0,0,0,0,0,0,0,15,0,0,0,C1orf105;chromosome 1 open reading frame 105,-,-,-,-
9235,0,0,0,0,0,0,0,43,16,0,1,0,IL32;interleukin 32,GO:0005615//extracellular space;GO:0016020//membrane,GO:0006952//defense response;GO:0006955//immune response;GO:0007155//cell adhesion,GO:0005125//cytokine activity;GO:0005515//protein binding,-
92359,98,5,0,0,5,17,0,0,17,41,0,0,CRB3;crumbs family member 3,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0005923//tight junction;GO:0016021//integral component of membrane;GO:0016324//apical plasma membrane;GO:0043234//protein complex,GO:0072659//protein localization to plasma membrane;GO:0045216//cell-cell junction organization;GO:0034329//cell junction assembly;GO:0070830//tight junction assembly,GO:0019904//protein domain specific binding;GO:0017124//SH3 domain binding,K06090//Tight junction
9236,0,0,0,12,21,13,18,0,26,0,0,0,CCPG1;cell cycle progression 1,GO:0016021//integral component of membrane,GO:2001106//regulation of Rho guanyl-nucleotide exchange factor activity;GO:0007049//cell cycle;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045787//positive regulation of cell cycle;GO:0008284//positive regulation of cell proliferation,-,K05286//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
92369,0,0,0,0,0,0,10,0,32,0,3,0,SPSB4;splA/ryanodine receptor domain and SOCS box containing 4,GO:0005737//cytoplasm,GO:0016567//protein ubiquitination;GO:0035556//intracellular signal transduction,GO:0005515//protein binding,-
92370,0,1,0,0,0,0,0,18,35,0,0,0,PXYLP1;2-phosphoxylose phosphatase 1,GO:0005576//extracellular region,GO:0016311//dephosphorylation,GO:0003993//acid phosphatase activity,K14395//Riboflavin metabolism;K01078//Tuberculosis;Aminobenzoate degradation;Microbial metabolism in diverse environments;Glycerophospholipid metabolism;Cell cycle - yeast;Ether lipid metabolism;Inositol phosphate metabolism;Riboflavin metabolism;Metabolic pathways
9238,0,1,0,0,18,0,15,0,16,0,0,0,TBRG4;transforming growth factor beta regulator 4,GO:0005739//mitochondrion,GO:0006468//protein phosphorylation;GO:0007050//cell cycle arrest;GO:0008284//positive regulation of cell proliferation;GO:0045333//cellular respiration,GO:0004672//protein kinase activity;GO:0044822//poly(A) RNA binding,-
92399,1,136,0,72,84,18,58,61,22,0,68,0,MRRF;mitochondrial ribosome recycling factor,GO:0005739//mitochondrion,GO:0032790//ribosome disassembly;GO:0006412//translation,-,-
924,0,0,0,0,0,0,60,0,23,0,0,0,CD7;CD7 molecule,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0048873//homeostasis of number of cells within a tissue;GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006955//immune response,GO:0004872//receptor activity,K06457//Hematopoietic cell lineage
9240,0,0,0,3,51,0,0,104,0,0,7,0,PNMA1;paraneoplastic Ma antigen 1,GO:0005737//cytoplasm;GO:0005730//nucleolus;GO:0005925//focal adhesion,GO:0002437//inflammatory response to antigenic stimulus;GO:0043065//positive regulation of apoptotic process,GO:0005515//protein binding,K04228//Neuroactive ligand-receptor interaction;Vasopressin-regulated water reabsorption
92400,5,17,0,54,67,12,2,19,35,0,10,0,RBM18;RNA binding motif protein 18,-,-,GO:0000166//nucleotide binding;GO:0003723//RNA binding,K12831//Spliceosome;K12842//Spliceosome
9241,0,0,0,0,0,0,0,0,0,0,16,0,NOG;noggin,GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0048570//notochord morphogenesis;GO:0090193//positive regulation of glomerulus development;GO:0009953//dorsal/ventral pattern formation;GO:0042733//embryonic digit morphogenesis;GO:0001706//endoderm formation;GO:0042060//wound healing;GO:2000313//regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation;GO:0061037//negative regulation of cartilage development;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0060325//face morphogenesis;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0001707//mesoderm formation;GO:0001701//in utero embryonic development;GO:0060173//limb development;GO:0021983//pituitary gland development;GO:0071773//cellular response to BMP stimulus;GO:0001837//epithelial to mesenchymal transition;GO:0045668//negative regulation of osteoblast differentiation;GO:0001839//neural plate morphogenesis;GO:0061053//somite development;GO:0007399//nervous system development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030514//negative regulation of BMP signaling pathway;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0021533//cell differentiation in hindbrain;GO:0008045//motor neuron axon guidance;GO:0060272//embryonic skeletal joint morphogenesis;GO:0060676//ureteric bud formation;GO:0060044//negative regulation of cardiac muscle cell proliferation;GO:0050679//positive regulation of epithelial cell proliferation;GO:0030336//negative regulation of cell migration;GO:0030509//BMP signaling pathway;GO:0048318//axial mesoderm development;GO:0021510//spinal cord development;GO:0060425//lung morphogenesis;GO:0051216//cartilage development;GO:2001234//negative regulation of apoptotic signaling pathway;GO:0001501//skeletal system development;GO:0048712//negative regulation of astrocyte differentiation;GO:0042474//middle ear morphogenesis;GO:0060302//negative regulation of cytokine activity;GO:0060394//negative regulation of pathway-restricted SMAD protein phosphorylation;GO:0048706//embryonic skeletal system development;GO:0001649//osteoblast differentiation;GO:0001843//neural tube closure;GO:0035019//somatic stem cell maintenance;GO:0060513//prostatic bud formation,GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0019955//cytokine binding,K04658//TGF-beta signaling pathway
9242,0,0,0,0,0,12,10,0,15,2,20,0,MSC;musculin,GO:0005634//nucleus,GO:0014707//branchiomeric skeletal muscle development;GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0060539//diaphragm development;GO:0060021//palate development,GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0046983//protein dimerization activity;GO:0003714//transcription corepressor activity;GO:0001206//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription,-
92421,0,22,36,41,55,0,6,0,3,0,51,0,CHMP4C;charged multivesicular body protein 4C,GO:0005829//cytosol;GO:0030496//midbody;GO:0090543//Flemming body;GO:0070062//extracellular vesicular exosome;GO:0031902//late endosome membrane,GO:0031565//cytokinesis checkpoint;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization;GO:0032466//negative regulation of cytokinesis;GO:1902188//positive regulation of viral release from host cell;GO:0016032//viral process;GO:0050792//regulation of viral process;GO:0019058//viral life cycle;GO:0009838//abscission,GO:0005515//protein binding;GO:0042803//protein homodimerization activity,K12194//Endocytosis
9244,0,0,0,0,0,0,0,0,8,0,14,0,CRLF1;cytokine receptor-like factor 1,GO:0005615//extracellular space;GO:0097058//CRLF-CLCF1 complex,GO:0042517//positive regulation of tyrosine phosphorylation of Stat3 protein;GO:0008284//positive regulation of cell proliferation;GO:2000672//negative regulation of motor neuron apoptotic process;GO:0043524//negative regulation of neuron apoptotic process;GO:0001657//ureteric bud development,GO:0005127//ciliary neurotrophic factor receptor binding;GO:0019955//cytokine binding;GO:0004872//receptor activity;GO:0005125//cytokine activity;GO:0005515//protein binding;GO:0046982//protein heterodimerization activity,K05081//Neuroactive ligand-receptor interaction;Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway;K05060//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
9245,0,0,0,0,0,21,0,0,0,0,5,0,"GCNT3;glucosaminyl (N-acetyl) transferase 3, mucin type",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,GO:0002426//immunoglobulin production in mucosal tissue;GO:0005975//carbohydrate metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0050892//intestinal absorption;GO:0044267//cellular protein metabolic process;GO:0060993//kidney morphogenesis;GO:0006493//protein O-linked glycosylation;GO:0048729//tissue morphogenesis,"GO:0003829//beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0047225//acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008109//N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity",K09662//Mucin type O-Glycan biosynthesis;Metabolic pathways
9246,0,0,15,1,75,0,0,0,27,0,0,0,UBE2L6;ubiquitin-conjugating enzyme E2L 6,GO:0005829//cytosol,GO:0019221//cytokine-mediated signaling pathway;GO:0032480//negative regulation of type I interferon production;GO:0016567//protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0019941//modification-dependent protein catabolic process;GO:0006464//cellular protein modification process;GO:0045087//innate immune response,GO:0042296//ISG15 ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding,K04553//Ubiquitin mediated proteolysis;Parkinson's disease
9247,0,0,0,0,0,0,0,0,9,0,5,0,GCM2;glial cells missing homolog 2 (Drosophila),GO:0005634//nucleus,"GO:0006874//cellular calcium ion homeostasis;GO:0030154//cell differentiation;GO:0060017//parathyroid gland development;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0071310//cellular response to organic substance;GO:0030643//cellular phosphate ion homeostasis;GO:0043066//negative regulation of apoptotic process;GO:0007275//multicellular organismal development",GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0003677//DNA binding,-
9248,0,0,0,0,0,2,0,73,25,0,12,0,GPR50;G protein-coupled receptor 50,GO:0005887//integral component of plasma membrane,GO:0007267//cell-cell signaling;GO:0007186//G-protein coupled receptor signaling pathway,GO:0004930//G-protein coupled receptor activity;GO:0008502//melatonin receptor activity;GO:0005515//protein binding;GO:0042802//identical protein binding,K04287//Neuroactive ligand-receptor interaction
92482,0,235,243,483,483,0,0,33,69,308,417,0,BBIP1;BBSome interacting protein 1,GO:0005737//cytoplasm;GO:0034464//BBSome;GO:0005929//cilium,GO:0015031//protein transport;GO:0042384//cilium assembly,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Salivary secretion;Cardiac muscle contraction;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
92483,0,0,0,12,0,17,1,0,0,0,6,0,LDHAL6B;lactate dehydrogenase A-like 6B,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0006096//glycolytic process;GO:0055114//oxidation-reduction process;GO:0044262//cellular carbohydrate metabolic process,GO:0004459//L-lactate dehydrogenase activity;GO:0005515//protein binding,K00016//Microbial metabolism in diverse environments;Pyruvate metabolism;Propanoate metabolism;Metabolic pathways;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis
9249,0,17,0,9,35,8,26,4,20,0,0,0,DHRS3;dehydrogenase/reductase (SDR family) member 3,GO:0042622//photoreceptor outer segment membrane;GO:0016021//integral component of membrane,"GO:0060021//palate development;GO:0007603//phototransduction, visible light;GO:0060349//bone morphogenesis;GO:0030278//regulation of ossification;GO:0055114//oxidation-reduction process;GO:0060411//cardiac septum morphogenesis;GO:0007601//visual perception;GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0003151//outflow tract morphogenesis;GO:0042572//retinol metabolic process;GO:0001523//retinoid metabolic process",GO:0009055//electron carrier activity;GO:0000166//nucleotide binding;GO:0052650//NADP-retinol dehydrogenase activity;GO:0004745//retinol dehydrogenase activity,K11146//Retinol metabolism;Metabolic pathways
925,0,0,0,0,0,7,21,0,7,48,5,0,CD8A;CD8a molecule,GO:0005886//plasma membrane;GO:0042101//T cell receptor complex;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0002456//T cell mediated immunity;GO:0050776//regulation of immune response;GO:0050850//positive regulation of calcium-mediated signaling;GO:0051607//defense response to virus;GO:0045065//cytotoxic T cell differentiation;GO:0042110//T cell activation;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0019882//antigen processing and presentation;GO:0006955//immune response,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0042803//protein homodimerization activity;GO:0015026//coreceptor activity;GO:0042288//MHC class I protein binding,K06458//Hematopoietic cell lineage;T cell receptor signaling pathway;Cell adhesion molecules (CAMs);Primary immunodeficiency;Antigen processing and presentation
9252,0,0,0,16,0,0,28,0,33,2,0,0,"RPS6KA5;ribosomal protein S6 kinase, 90kDa, polypeptide 5",GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0007411//axon guidance;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0043988//histone H3-S28 phosphorylation;GO:0034166//toll-like receptor 10 signaling pathway;GO:0002224//toll-like receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0043990//histone H2A-S1 phosphorylation;GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0045892//negative regulation of transcription, DNA-templated;GO:0033129//positive regulation of histone phosphorylation;GO:0016572//histone phosphorylation;GO:0043987//histone H3-S10 phosphorylation;GO:0006954//inflammatory response;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0070498//interleukin-1-mediated signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0035556//intracellular signal transduction;GO:0035066//positive regulation of histone acetylation;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0045087//innate immune response;GO:0034162//toll-like receptor 9 signaling pathway;GO:0032793//positive regulation of CREB transcription factor activity;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0001818//negative regulation of cytokine production",GO:0005515//protein binding;GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0000287//magnesium ion binding;GO:0005524//ATP binding,K04445//MAPK signaling pathway;Neurotrophin signaling pathway;Bladder cancer
92521,84,1,1,23,104,7,75,111,55,0,4,122,SPECC1;sperm antigen with calponin homology and coiled-coil domains 1,GO:0005634//nucleus,GO:0007155//cell adhesion,-,K05699//Adherens junction;Amoebiasis;Focal adhesion;Systemic lupus erythematosus;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Tight junction;K06115//Tight junction;K12478//Phagosome;Endocytosis;Tuberculosis;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
9253,57,1,1,0,0,25,11,0,33,0,0,0,NUMBL;numb homolog (Drosophila)-like,GO:0005737//cytoplasm,GO:0019221//cytokine-mediated signaling pathway;GO:0007399//nervous system development;GO:0021849//neuroblast division in subventricular zone;GO:0021670//lateral ventricle development;GO:0050769//positive regulation of neurogenesis;GO:0034332//adherens junction organization;GO:0007409//axonogenesis;GO:0050775//positive regulation of dendrite morphogenesis;GO:0019538//protein metabolic process,GO:0005515//protein binding,K06057//Notch signaling pathway
9254,0,84,1,60,113,0,4,94,59,0,201,25,"CACNA2D2;calcium channel, voltage-dependent, alpha 2/delta subunit 2",GO:0005886//plasma membrane;GO:0005891//voltage-gated calcium channel complex,GO:0034765//regulation of ion transmembrane transport;GO:0046622//positive regulation of organ growth;GO:0070588//calcium ion transmembrane transport;GO:0050796//regulation of insulin secretion;GO:0006112//energy reserve metabolic process;GO:0044281//small molecule metabolic process;GO:0007528//neuromuscular junction development;GO:0060024//rhythmic synaptic transmission;GO:0040014//regulation of multicellular organism growth;GO:0048747//muscle fiber development,GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding,K04859//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway;Cardiac muscle contraction;Dilated cardiomyopathy
9255,0,128,285,242,231,0,74,171,0,0,243,0,AIMP1;aminoacyl tRNA synthetase complex-interacting multifunctional protein 1,GO:0016020//membrane;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0005794//Golgi apparatus;GO:0030133//transport vesicle;GO:0005615//extracellular space;GO:0005829//cytosol;GO:0017101//aminoacyl-tRNA synthetase multienzyme complex;GO:0005634//nucleus,GO:0001525//angiogenesis;GO:0006006//glucose metabolic process;GO:0050900//leukocyte migration;GO:0007165//signal transduction;GO:0009611//response to wounding;GO:0001937//negative regulation of endothelial cell proliferation;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response;GO:0007155//cell adhesion;GO:0010467//gene expression;GO:0006418//tRNA aminoacylation for protein translation;GO:0006935//chemotaxis;GO:0006915//apoptotic process,GO:0000049//tRNA binding;GO:0042803//protein homodimerization activity;GO:0005125//cytokine activity;GO:0005515//protein binding,-
92552,0,0,0,0,0,0,0,0,0,1,0,0,ATXN3L;ataxin 3-like,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006508//proteolysis;GO:0016579//protein deubiquitination;GO:0006355//regulation of transcription, DNA-templated",GO:0008242//omega peptidase activity;GO:0004843//ubiquitin-specific protease activity,K11863//Protein processing in endoplasmic reticulum
92558,0,0,0,0,3,0,0,0,0,0,16,0,CCDC64;coiled-coil domain containing 64,GO:0005737//cytoplasm;GO:0005813//centrosome,GO:0031175//neuron projection development;GO:0055107//Golgi to secretory granule transport,GO:0034452//dynactin binding;GO:0017137//Rab GTPase binding,-
9256,114,0,0,3,0,0,33,4,157,125,67,1,BZRAP1;benzodiazepine receptor (peripheral) associated protein 1,GO:0005737//cytoplasm;GO:0005739//mitochondrion,-,GO:0030156//benzodiazepine receptor binding;GO:0005515//protein binding,K13738//Bacterial invasion of epithelial cells;K04437//Salmonella infection;MAPK signaling pathway;Focal adhesion
92565,0,22,0,0,0,0,0,0,44,0,0,139,FANK1;fibronectin type III and ankyrin repeat domains 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,-,-
92579,0,0,0,0,0,0,1,0,37,0,0,0,"G6PC3;glucose 6 phosphatase, catalytic, 3",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006094//gluconeogenesis;GO:0015758//glucose transport;GO:0016311//dephosphorylation;GO:0055085//transmembrane transport;GO:0015760//glucose-6-phosphate transport;GO:0051156//glucose 6-phosphate metabolic process;GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process,GO:0004346//glucose-6-phosphatase activity,K01084//Carbohydrate digestion and absorption;Glycolysis / Gluconeogenesis;Starch and sucrose metabolism;Insulin signaling pathway;Metabolic pathways;Galactose metabolism;Adipocytokine signaling pathway
9258,84,0,0,17,1,0,13,0,10,0,21,0,MFHAS1;malignant fibrous histiocytoma amplified sequence 1,-,-,GO:0005515//protein binding,K01768//Purine metabolism;Meiosis - yeast
92591,0,25,23,9,60,16,3,73,25,0,121,0,ASB16;ankyrin repeat and SOCS box containing 16,-,GO:0035556//intracellular signal transduction;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
92595,0,0,0,0,0,11,0,0,0,0,18,0,ZNF764;zinc finger protein 764,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
92597,97,16,0,54,208,0,17,103,55,0,0,0,MOB1B;MOB kinase activator 1B,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0035329//hippo signaling;GO:0042327//positive regulation of phosphorylation;GO:0046777//protein autophosphorylation,GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0019209//kinase activator activity;GO:0019900//kinase binding,K06685//Cell cycle - yeast
926,0,0,0,0,0,65,9,80,1,79,1,0,CD8B;CD8b molecule,GO:0042101//T cell receptor complex;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0031901//early endosome membrane;GO:0005887//integral component of plasma membrane,GO:0016032//viral process;GO:0006955//immune response;GO:0050776//regulation of immune response;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0042110//T cell activation,GO:0005515//protein binding;GO:0042288//MHC class I protein binding;GO:0015026//coreceptor activity,K06459//Antigen processing and presentation;Cell adhesion molecules (CAMs);Primary immunodeficiency;T cell receptor signaling pathway;Hematopoietic cell lineage
9260,87,0,0,0,0,0,16,0,0,0,0,0,PDLIM7;PDZ and LIM domain 7 (enigma),GO:0005925//focal adhesion;GO:0001726//ruffle;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0001725//stress fiber;GO:0005634//nucleus,GO:0007275//multicellular organismal development;GO:0045669//positive regulation of osteoblast differentiation;GO:0030036//actin cytoskeleton organization;GO:0006898//receptor-mediated endocytosis;GO:0030154//cell differentiation;GO:0001503//ossification,GO:0008270//zinc ion binding;GO:0005515//protein binding,K05760//Chemokine signaling pathway;Bacterial invasion of epithelial cells;Regulation of actin cytoskeleton;Leukocyte transendothelial migration;VEGF signaling pathway;Focal adhesion;K05629//Tight junction
92609,1,0,0,0,1,0,0,0,33,0,25,0,TIMM50;translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae),GO:0005739//mitochondrion;GO:0016607//nuclear speck;GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane;GO:0005744//mitochondrial inner membrane presequence translocase complex,GO:0007006//mitochondrial membrane organization;GO:0044267//cellular protein metabolic process;GO:0006470//protein dephosphorylation;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001836//release of cytochrome c from mitochondria;GO:0006626//protein targeting to mitochondrion,GO:0043021//ribonucleoprotein complex binding;GO:0004721//phosphoprotein phosphatase activity;GO:0005134//interleukin-2 receptor binding;GO:0005515//protein binding;GO:0004725//protein tyrosine phosphatase activity;GO:0003723//RNA binding;GO:0004722//protein serine/threonine phosphatase activity,-
9261,30,40,0,13,0,0,0,0,19,0,0,0,MAPKAPK2;mitogen-activated protein kinase-activated protein kinase 2,GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0048839//inner ear development;GO:0016070//RNA metabolic process;GO:0006950//response to stress;GO:0034162//toll-like receptor 9 signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0019369//arachidonic acid metabolic process;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032675//regulation of interleukin-6 production;GO:0007265//Ras protein signal transduction;GO:0031572//G2 DNA damage checkpoint;GO:0006691//leukotriene metabolic process;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0034146//toll-like receptor 5 signaling pathway;GO:0010467//gene expression;GO:0070935//3'-UTR-mediated mRNA stabilization;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0016071//mRNA metabolic process;GO:0006974//cellular response to DNA damage stimulus;GO:0006954//inflammatory response;GO:0032680//regulation of tumor necrosis factor production;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0034097//response to cytokine;GO:0044281//small molecule metabolic process;GO:0034134//toll-like receptor 2 signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0034166//toll-like receptor 10 signaling pathway;GO:0032496//response to lipopolysaccharide;GO:0044351//macropinocytosis;GO:0002224//toll-like receptor signaling pathway,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0004672//protein kinase activity,K04443//Neurotrophin signaling pathway;MAPK signaling pathway;VEGF signaling pathway
92610,0,0,0,11,33,0,0,0,37,0,0,0,TIFA;TRAF-interacting protein with forkhead-associated domain,-,GO:0007249//I-kappaB kinase/NF-kappaB signaling,GO:0005515//protein binding,-
9262,256,1,1,53,50,0,18,0,44,0,0,287,STK17B;serine/threonine kinase 17b,GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005634//nucleus;GO:0015629//actin cytoskeleton;GO:0005886//plasma membrane,GO:0006915//apoptotic process;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0046777//protein autophosphorylation,GO:0004672//protein kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
9263,0,16,1,49,81,0,48,0,44,0,16,0,STK17A;serine/threonine kinase 17a,GO:0005634//nucleus,GO:0006915//apoptotic process;GO:2000377//regulation of reactive oxygen species metabolic process;GO:2000271//positive regulation of fibroblast apoptotic process;GO:0006468//protein phosphorylation;GO:0035556//intracellular signal transduction;GO:0043065//positive regulation of apoptotic process,GO:0004674//protein serine/threonine kinase activity;GO:0005524//ATP binding,-
9265,2,1,0,5,20,0,26,0,39,102,0,0,CYTH3;cytohesin 3,GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005829//cytosol;GO:0001726//ruffle;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network,GO:0016192//vesicle-mediated transport;GO:0030155//regulation of cell adhesion;GO:0032012//regulation of ARF protein signal transduction;GO:0090162//establishment of epithelial cell polarity;GO:0048193//Golgi vesicle transport;GO:0043547//positive regulation of GTPase activity;GO:0045785//positive regulation of cell adhesion,"GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity",K12495//Endocytosis
9266,0,0,33,0,0,1,8,0,49,0,0,0,CYTH2;cytohesin 2,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005802//trans-Golgi network,GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization;GO:0006897//endocytosis;GO:0030155//regulation of cell adhesion;GO:0032012//regulation of ARF protein signal transduction;GO:0043547//positive regulation of GTPase activity,"GO:0005086//ARF guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0070679//inositol 1,4,5 trisphosphate binding;GO:0008289//lipid binding",K12495//Endocytosis
92667,0,0,0,15,12,0,9,0,24,0,0,0,MGME1;mitochondrial genome maintenance exonuclease 1,GO:0005739//mitochondrion,"GO:0006264//mitochondrial DNA replication;GO:0043504//mitochondrial DNA repair;GO:0000738//DNA catabolic process, exonucleolytic;GO:0000002//mitochondrial genome maintenance",GO:0008297//single-stranded DNA exodeoxyribonuclease activity,-
9267,0,25,2,0,61,0,0,86,39,0,0,0,CYTH1;cytohesin 1,GO:0005829//cytosol;GO:0031234//extrinsic component of cytoplasmic side of plasma membrane;GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network;GO:0005737//cytoplasm,GO:0016192//vesicle-mediated transport;GO:0030155//regulation of cell adhesion;GO:0032012//regulation of ARF protein signal transduction;GO:0090162//establishment of epithelial cell polarity;GO:0043547//positive regulation of GTPase activity,GO:0008289//lipid binding;GO:0005515//protein binding;GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
92675,0,0,0,0,19,13,0,0,31,0,15,0,DTD1;D-tyrosyl-tRNA deacylase 1,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0019478//D-amino acid catabolic process;GO:0006260//DNA replication,"GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0016788//hydrolase activity, acting on ester bonds",-
92689,24,2,0,6,66,1,26,71,59,0,3,0,"FAM114A1;family with sequence similarity 114, member A1",GO:0005737//cytoplasm,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways
92691,0,0,0,0,0,12,0,42,11,0,7,0,TMEM169;transmembrane protein 169,GO:0016021//integral component of membrane,-,-,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K01539//Oxidative phosphorylation;Bile secretion;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;K11447//Transcriptional misregulation in cancer
9270,0,1,0,0,24,0,0,0,37,0,3,0,ITGB1BP1;integrin beta 1 binding protein 1,GO:0071944//cell periphery;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005925//focal adhesion;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0030027//lamellipodium;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0001726//ruffle,"GO:0016477//cell migration;GO:0051781//positive regulation of cell division;GO:0032148//activation of protein kinase B activity;GO:0031214//biomineral tissue development;GO:0006933//negative regulation of cell adhesion involved in substrate-bound cell migration;GO:0010764//negative regulation of fibroblast migration;GO:0043113//receptor clustering;GO:0008284//positive regulation of cell proliferation;GO:0051897//positive regulation of protein kinase B signaling;GO:0090315//negative regulation of protein targeting to membrane;GO:0035924//cellular response to vascular endothelial growth factor stimulus;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0010595//positive regulation of endothelial cell migration;GO:0006351//transcription, DNA-templated;GO:0032091//negative regulation of protein binding;GO:0033622//integrin activation;GO:0008285//negative regulation of cell proliferation;GO:0035556//intracellular signal transduction;GO:2001044//regulation of integrin-mediated signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0043088//regulation of Cdc42 GTPase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0030154//cell differentiation;GO:0007229//integrin-mediated signaling pathway;GO:0007219//Notch signaling pathway;GO:0035148//tube formation;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0007160//cell-matrix adhesion;GO:0050880//regulation of blood vessel size;GO:0051451//myoblast migration;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0045747//positive regulation of Notch signaling pathway;GO:1900025//negative regulation of substrate adhesion-dependent cell spreading;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0090314//positive regulation of protein targeting to membrane;GO:0051895//negative regulation of focal adhesion assembly;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0006469//negative regulation of protein kinase activity;GO:0051894//positive regulation of focal adhesion assembly;GO:0015031//protein transport",GO:0008565//protein transporter activity;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0005092//GDP-dissociation inhibitor activity;GO:0005178//integrin binding;GO:0019901//protein kinase binding,-
9271,0,0,0,1,12,25,39,0,41,0,0,0,PIWIL1;piwi-like RNA-mediated gene silencing 1,GO:0043186//P granule;GO:0005737//cytoplasm;GO:0005844//polysome;GO:0005845//mRNA cap binding complex;GO:0033391//chromatoid body,GO:0031047//gene silencing by RNA;GO:0007286//spermatid development;GO:0007126//meiotic nuclear division;GO:0034587//piRNA metabolic process;GO:0007275//multicellular organismal development;GO:0006417//regulation of translation,GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0003727//single-stranded RNA binding;GO:0003729//mRNA binding;GO:0034584//piRNA binding,K02156//Dorso-ventral axis formation
92714,0,55,0,1,21,0,0,74,0,0,18,0,ARRDC1;arrestin domain containing 1,GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,-,-,-
92715,0,0,0,0,17,0,0,0,26,0,0,0,DPH7;diphthamide biosynthesis 7,-,GO:0017183//peptidyl-diphthamide biosynthetic process from peptidyl-histidine,-,K13341//Peroxisome
92736,0,0,0,0,0,0,15,0,17,0,0,0,OTOP2;otopetrin 2,GO:0016021//integral component of membrane,-,-,-
92737,0,0,14,0,0,0,2,85,79,0,0,92,DNER;delta/notch-like EGF repeat containing,GO:0016021//integral component of membrane;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005769//early endosome;GO:0043025//neuronal cell body,GO:0006897//endocytosis;GO:0001764//neuron migration;GO:0007220//Notch receptor processing;GO:0007417//central nervous system development;GO:0007416//synapse assembly;GO:0010001//glial cell differentiation;GO:0048741//skeletal muscle fiber development;GO:0007219//Notch signaling pathway,GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0005112//Notch binding;GO:0030276//clathrin binding,K02599//Notch signaling pathway;Dorso-ventral axis formation;Prion diseases
9274,0,0,35,0,0,10,0,52,26,118,11,0,BCL7C;B-cell CLL/lymphoma 7C,-,GO:0006915//apoptotic process,-,-
92745,0,0,0,0,0,8,0,62,24,0,0,0,"SLC38A5;solute carrier family 38, member 5",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0006811//ion transport;GO:0006865//amino acid transport;GO:0003333//amino acid transmembrane transport;GO:0015816//glycine transport;GO:0055085//transmembrane transport,GO:0015187//glycine transmembrane transporter activity,K14992//GABAergic synapse
92747,0,0,0,0,0,14,19,0,34,126,6,0,"BPIFB1;BPI fold containing family B, member 1",GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region,GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0002227//innate immune response in mucosa,GO:0008289//lipid binding,-
92749,0,0,0,0,0,22,4,0,16,101,0,0,DRC1;dynein regulatory complex subunit 1 homolog (Chlamydomonas),GO:0005856//cytoskeleton;GO:0005930//axoneme,GO:0060285//cilium-dependent cell motility;GO:0071973//bacterial-type flagellum-dependent cell motility;GO:0070286//axonemal dynein complex assembly,-,K05702//Tight junction;Adherens junction;Leukocyte transendothelial migration;K08836//Oocyte meiosis;K06084//Adherens junction
9275,0,0,0,0,0,0,0,0,17,0,0,0,BCL7B;B-cell CLL/lymphoma 7B,-,-,GO:0003779//actin binding,-
9276,0,249,5,100,544,9,0,0,39,0,0,0,"COPB2;coatomer protein complex, subunit beta 2 (beta prime)",GO:0030126//COPI vesicle coat;GO:0005829//cytosol,"GO:0061024//membrane organization;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0006886//intracellular protein transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0048205//COPI coating of Golgi vesicle",GO:0005198//structural molecule activity,-
9277,0,0,0,0,3,0,1,0,1,0,0,0,WDR46;WD repeat domain 46,-,-,GO:0044822//poly(A) RNA binding,-
9278,0,0,0,0,2,0,0,0,0,0,0,0,ZBTB22;zinc finger and BTB domain containing 22,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
92797,0,0,0,0,23,0,21,0,59,0,0,0,HELB;helicase (DNA) B,GO:0005658//alpha DNA polymerase:primase complex,"GO:0006260//DNA replication;GO:0032508//DNA duplex unwinding;GO:0006269//DNA replication, synthesis of RNA primer",GO:0017116//single-stranded DNA-dependent ATP-dependent DNA helicase activity;GO:0005524//ATP binding;GO:0043141//ATP-dependent 5'-3' DNA helicase activity,-
92799,3,11,0,0,3,0,0,0,14,0,0,0,SHKBP1;SH3KBP1 binding protein 1,-,GO:0051260//protein homooligomerization,-,K08023//TGF-beta signaling pathway
928,0,33,0,68,114,0,0,0,21,0,0,0,CD9;CD9 molecule,GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0031092//platelet alpha granule membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005925//focal adhesion,GO:0032504//multicellular organism reproduction;GO:0007342//fusion of sperm to egg plasma membrane;GO:0009414//response to water deprivation;GO:0007596//blood coagulation;GO:0008285//negative regulation of cell proliferation;GO:0002576//platelet degranulation;GO:0007420//brain development;GO:0007155//cell adhesion;GO:0006928//cellular component movement;GO:0030913//paranodal junction assembly;GO:0014003//oligodendrocyte development;GO:0007338//single fertilization;GO:0030168//platelet activation,GO:0005178//integrin binding;GO:0005515//protein binding,K06460//Hematopoietic cell lineage
92806,0,0,0,8,34,0,29,0,14,0,10,0,CENPBD1;CENPB DNA-binding domains containing 1,GO:0005634//nucleus,-,GO:0003677//DNA binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K04514//Focal adhesion;Pathogenic Escherichia coli infection;Wnt signaling pathway;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Salmonella infection;Axon guidance;Chemokine signaling pathway
92815,0,33,1,0,0,0,0,0,0,0,0,0,"HIST3H2A;histone cluster 3, H2a",GO:0070062//extracellular vesicular exosome;GO:0000788//nuclear nucleosome,GO:0070914//UV-damage excision repair;GO:0006337//nucleosome disassembly,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Systemic lupus erythematosus;Alcoholism
9282,0,33,0,23,93,17,1,0,119,267,0,0,MED14;mediator complex subunit 14,GO:0016020//membrane;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0019827//stem cell maintenance;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001104//RNA polymerase II transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042809//vitamin D receptor binding;GO:0046966//thyroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0003713//transcription coactivator activity;GO:0004872//receptor activity,-
92822,0,20,5,20,55,25,0,58,53,0,16,0,ZNF276;zinc finger protein 276,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0008270//zinc ion binding,K10888//Fanconi anemia pathway
9283,0,0,0,0,0,0,0,0,38,0,0,0,GPR37L1;G protein-coupled receptor 37 like 1,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0043235//receptor complex,GO:0045665//negative regulation of neuron differentiation;GO:0048712//negative regulation of astrocyte differentiation;GO:0045879//negative regulation of smoothened signaling pathway;GO:0021940//positive regulation of cerebellar granule cell precursor proliferation;GO:0007186//G-protein coupled receptor signaling pathway,GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity,-
9284,0,0,0,0,1,0,0,0,0,0,0,0,"NPIPA1;nuclear pore complex interacting protein family, member A1",GO:0031965//nuclear membrane;GO:0005643//nuclear pore,GO:0015031//protein transport;GO:0051028//mRNA transport,-,-
92840,0,17,0,0,14,15,29,0,11,0,0,0,REEP6;receptor accessory protein 6,GO:0045177//apical part of cell;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0016021//integral component of membrane,GO:0032386//regulation of intracellular transport,-,-
92856,1,0,0,0,18,0,0,71,19,0,0,2,"IMP4;IMP4, U3 small nucleolar ribonucleoprotein",GO:0030529//ribonucleoprotein complex;GO:0005730//nucleolus,GO:0006364//rRNA processing,GO:0005515//protein binding,K14561//Ribosome biogenesis in eukaryotes
9289,152,0,0,0,3,0,40,12,57,0,11,0,GPR56;G protein-coupled receptor 56,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0097451//glial limiting end-foot;GO:0016021//integral component of membrane,GO:0007267//cell-cell signaling;GO:2001223//negative regulation of neuron migration;GO:0045785//positive regulation of cell adhesion;GO:0007266//Rho protein signal transduction;GO:0001525//angiogenesis;GO:0021801//cerebral cortex radial glia guided migration;GO:0021819//layer formation in cerebral cortex;GO:0035025//positive regulation of Rho protein signal transduction;GO:0007218//neuropeptide signaling pathway;GO:0070528//protein kinase C signaling;GO:0010573//vascular endothelial growth factor production;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008285//negative regulation of cell proliferation;GO:0007420//brain development;GO:0007155//cell adhesion,GO:0005518//collagen binding;GO:0004930//G-protein coupled receptor activity;GO:0050840//extracellular matrix binding,-
929,0,76,1,28,47,0,20,0,1,154,25,0,CD14;CD14 molecule,GO:0005615//extracellular space;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005576//extracellular region;GO:0031225//anchored component of membrane,GO:0034612//response to tumor necrosis factor;GO:0007166//cell surface receptor signaling pathway;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0006915//apoptotic process;GO:0045807//positive regulation of endocytosis;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0006909//phagocytosis;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0006954//inflammatory response;GO:0071222//cellular response to lipopolysaccharide;GO:0032026//response to magnesium ion;GO:0050715//positive regulation of cytokine secretion;GO:0002224//toll-like receptor signaling pathway;GO:0009408//response to heat;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0034142//toll-like receptor 4 signaling pathway;GO:0045471//response to ethanol;GO:0007249//I-kappaB kinase/NF-kappaB signaling;GO:0045087//innate immune response;GO:0034134//toll-like receptor 2 signaling pathway;GO:0071223//cellular response to lipoteichoic acid;GO:0034138//toll-like receptor 3 signaling pathway;GO:0032760//positive regulation of tumor necrosis factor production;GO:0002755//MyD88-dependent toll-like receptor signaling pathway,GO:0070891//lipoteichoic acid binding;GO:0001530//lipopolysaccharide binding;GO:0005515//protein binding;GO:0001847//opsonin receptor activity;GO:0016019//peptidoglycan receptor activity,K04391//Salmonella infection;NF-kappa B signaling pathway;Phagosome;Tuberculosis;Transcriptional misregulation in cancer;Pertussis;Legionellosis;Toll-like receptor signaling pathway;MAPK signaling pathway;Hematopoietic cell lineage;Regulation of actin cytoskeleton;Pathogenic Escherichia coli infection;Amoebiasis
9290,0,0,0,0,0,10,0,52,32,0,0,1,GPR55;G protein-coupled receptor 55,GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0045671//negative regulation of osteoclast differentiation;GO:0038171//cannabinoid signaling pathway;GO:0035025//positive regulation of Rho protein signal transduction;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045453//bone resorption;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007202//activation of phospholipase C activity,GO:0004930//G-protein coupled receptor activity;GO:0004949//cannabinoid receptor activity,-
92906,0,0,0,6,12,24,48,0,22,0,2,0,HNRNPLL;heterogeneous nuclear ribonucleoprotein L-like,GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005634//nucleus,GO:0033120//positive regulation of RNA splicing;GO:0006397//mRNA processing,GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003729//mRNA binding,-
92912,28,36,1,21,146,0,0,25,49,0,13,0,UBE2Q2;ubiquitin-conjugating enzyme E2Q family member 2,GO:0005737//cytoplasm,GO:0070936//protein K48-linked ubiquitination,GO:0004842//ubiquitin-protein transferase activity;GO:0016881//acid-amino acid ligase activity;GO:0005524//ATP binding,K10582//Ubiquitin mediated proteolysis
92922,0,0,0,0,0,0,0,0,32,1,4,0,CCDC102A;coiled-coil domain containing 102A,-,-,-,K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Vascular smooth muscle contraction;Regulation of actin cytoskeleton
92935,0,0,0,0,0,0,0,0,4,0,0,0,"MARS2;methionyl-tRNA synthetase 2, mitochondrial",GO:0005759//mitochondrial matrix,GO:0010467//gene expression;GO:0006431//methionyl-tRNA aminoacylation;GO:0006418//tRNA aminoacylation for protein translation;GO:0008219//cell death,GO:0005524//ATP binding;GO:0004825//methionine-tRNA ligase activity,K01874//Base excision repair;Selenocompound metabolism;Aminoacyl-tRNA biosynthesis
9294,0,0,0,0,0,15,0,0,0,0,0,0,S1PR2;sphingosine-1-phosphate receptor 2,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0003376//sphingosine-1-phosphate signaling pathway;GO:0000187//activation of MAPK activity;GO:0008284//positive regulation of cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0090394//negative regulation of excitatory postsynaptic membrane potential,GO:0001664//G-protein coupled receptor binding;GO:0004930//G-protein coupled receptor activity;GO:0008289//lipid binding;GO:0005178//integrin binding;GO:0038036//sphingosine-1-phosphate receptor activity,K04292//Neuroactive ligand-receptor interaction
92949,0,0,0,0,0,78,118,6,94,0,0,0,ADAMTSL1;ADAMTS-like 1,GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
9295,39,31,0,13,34,0,0,0,15,0,0,0,SRSF11;serine/arginine-rich splicing factor 11,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription;GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing",GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
9296,0,0,0,1,1,0,25,0,0,0,0,0,"ATP6V1F;ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F","GO:0016469//proton-transporting two-sector ATPase complex;GO:0033180//proton-transporting V-type ATPase, V1 domain;GO:0070062//extracellular vesicular exosome;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005829//cytosol;GO:0016020//membrane",GO:0051701//interaction with host;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0006200//ATP catabolic process;GO:0006879//cellular iron ion homeostasis;GO:0015991//ATP hydrolysis coupled proton transport;GO:0015992//proton transport;GO:0008286//insulin receptor signaling pathway;GO:0055085//transmembrane transport,"GO:0015078//hydrogen ion transmembrane transporter activity;GO:0005515//protein binding;GO:0046961//proton-transporting ATPase activity, rotational mechanism;GO:0042624//ATPase activity, uncoupled",K02151//Synaptic vesicle cycle;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Oxidative phosphorylation;Metabolic pathways
92960,0,0,0,0,0,0,0,0,0,53,0,1,PEX11G;peroxisomal biogenesis factor 11 gamma,GO:0043234//protein complex;GO:0005777//peroxisome;GO:0005779//integral component of peroxisomal membrane,GO:0016559//peroxisome fission;GO:0044375//regulation of peroxisome size,GO:0005515//protein binding,K13353//Peroxisome
92979,2,0,0,0,0,8,0,1,0,0,0,0,MARCH9;membrane-associated ring finger (C3HC4) 9,GO:0005802//trans-Golgi network;GO:0005765//lysosomal membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005795//Golgi stack,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0016874//ligase activity,-
92999,0,0,89,0,2,0,46,99,57,0,38,87,ZBTB47;zinc finger and BTB domain containing 47,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
93,0,0,0,9,10,31,0,0,33,123,6,148,"ACVR2B;activin A receptor, type IIB",GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane;GO:0005737//cytoplasm,"GO:0060021//palate development;GO:0030509//BMP signaling pathway;GO:0032927//positive regulation of activin receptor signaling pathway;GO:0035265//organ growth;GO:0032147//activation of protein kinase activity;GO:0009749//response to glucose;GO:0007507//heart development;GO:0001822//kidney development;GO:0061298//retina vasculature development in camera-type eye;GO:0060836//lymphatic endothelial cell differentiation;GO:0007178//transmembrane receptor protein serine/threonine kinase signaling pathway;GO:0060840//artery development;GO:0042475//odontogenesis of dentin-containing tooth;GO:0048617//embryonic foregut morphogenesis;GO:0001946//lymphangiogenesis;GO:0030073//insulin secretion;GO:0009952//anterior/posterior pattern specification;GO:0023014//signal transduction by phosphorylation;GO:0030501//positive regulation of bone mineralization;GO:0007368//determination of left/right symmetry;GO:0001702//gastrulation with mouth forming second;GO:0009791//post-embryonic development;GO:0060841//venous blood vessel development;GO:0031016//pancreas development;GO:0007498//mesoderm development;GO:0045669//positive regulation of osteoblast differentiation;GO:0001974//blood vessel remodeling;GO:0032924//activin receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0030324//lung development;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0048705//skeletal system morphogenesis","GO:0034711//inhibin binding;GO:0005524//ATP binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0004712//protein serine/threonine/tyrosine kinase activity;GO:0005024//transforming growth factor beta-activated receptor activity;GO:0016362//activin receptor activity, type II;GO:0019838//growth factor binding;GO:0004674//protein serine/threonine kinase activity;GO:0046872//metal ion binding;GO:0048185//activin binding;GO:0005515//protein binding",K13596//Cytokine-cytokine receptor interaction;TGF-beta signaling pathway
930,71,0,0,0,0,0,44,0,3,39,5,0,CD19;CD19 molecule,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005887//integral component of plasma membrane,GO:0006968//cellular defense response;GO:0007166//cell surface receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045087//innate immune response;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0050776//regulation of immune response;GO:0050853//B cell receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0005057//receptor signaling protein activity,K06465//Epstein-Barr virus infection;B cell receptor signaling pathway;Primary immunodeficiency;Hematopoietic cell lineage
93010,0,0,0,0,0,0,0,0,37,0,0,0,"B3GNT7;UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7",GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0044267//cellular protein metabolic process;GO:0043687//post-translational protein modification;GO:0016266//O-glycan processing;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process,GO:0008378//galactosyltransferase activity,K09664//Glycosaminoglycan biosynthesis - keratan sulfate
9303,0,0,0,0,0,0,0,0,28,0,8,0,"SNORD25;small nucleolar RNA, C/D box 25",-,-,-,-
93034,0,0,54,12,10,0,0,0,0,0,41,0,"NT5C1B;5'-nucleotidase, cytosolic IB",GO:0005634//nucleus;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0006144//purine nucleobase metabolic process;GO:0006195//purine nucleotide catabolic process;GO:0016311//dephosphorylation,GO:0000166//nucleotide binding;GO:0000287//magnesium ion binding;GO:0008253//5'-nucleotidase activity,K01081//Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
93035,87,0,0,0,0,32,17,0,173,0,30,0,PKHD1L1;polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1,GO:0005615//extracellular space;GO:0005829//cytosol;GO:0016021//integral component of membrane,GO:0006955//immune response,GO:0004872//receptor activity,K05099//Adherens junction;Epithelial cell signaling in Helicobacter pylori infection;Renal cell carcinoma;Focal adhesion;Melanoma;Cytokine-cytokine receptor interaction;Transcriptional misregulation in cancer;Malaria;Pathways in cancer;Axon guidance;Bacterial invasion of epithelial cells;Endocytosis;K06820//Axon guidance
93058,0,0,0,0,9,0,0,0,16,0,0,0,COQ10A;coenzyme Q10 homolog A (S. cerevisiae),GO:0005743//mitochondrial inner membrane,-,-,-
9306,0,1,2,12,109,16,0,62,0,0,0,0,SOCS6;suppressor of cytokine signaling 6,GO:0001772//immunological synapse;GO:0005737//cytoplasm,GO:0006952//defense response;GO:0040008//regulation of growth;GO:0050868//negative regulation of T cell activation;GO:0007259//JAK-STAT cascade;GO:0010498//proteasomal protein catabolic process;GO:0009968//negative regulation of signal transduction;GO:0016567//protein ubiquitination,GO:0005515//protein binding,-
9308,1,0,13,0,0,0,0,0,4,0,1,0,CD83;CD83 molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,"GO:0043372//positive regulation of CD4-positive, alpha-beta T cell differentiation;GO:0014070//response to organic cyclic compound;GO:0006952//defense response;GO:0032713//negative regulation of interleukin-4 production;GO:0007165//signal transduction;GO:0032733//positive regulation of interleukin-10 production;GO:0006959//humoral immune response;GO:0032743//positive regulation of interleukin-2 production",-,-
93081,0,0,0,0,0,13,0,0,0,0,0,0,TEX30;testis expressed 30,-,-,-,-
93082,0,0,0,0,0,0,25,0,21,0,0,0,NEURL3;neuralized E3 ubiquitin protein ligase 3,-,GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0016874//ligase activity,-
93099,173,0,0,0,4,0,0,111,15,0,0,0,DMKN;dermokine,GO:0070062//extracellular vesicular exosome;GO:0005615//extracellular space,-,GO:0005515//protein binding,-
931,0,0,0,0,0,0,56,0,43,0,0,0,"MS4A1;membrane-spanning 4-domains, subfamily A, member 1",GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005615//extracellular space,GO:0006959//humoral immune response;GO:0042100//B cell proliferation,GO:0005154//epidermal growth factor receptor binding;GO:0023026//MHC class II protein complex binding,K06466//Hematopoietic cell lineage
9310,0,0,0,0,0,0,33,0,45,0,12,0,ZNF235;zinc finger protein 235,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
93100,0,0,0,0,0,0,0,0,30,0,0,0,NAPRT;nicotinate phosphoribosyltransferase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0019358//nicotinate nucleotide salvage;GO:0006769//nicotinamide metabolic process;GO:0006979//response to oxidative stress;GO:0019674//NAD metabolic process;GO:0009435//NAD biosynthetic process;GO:0006766//vitamin metabolic process,GO:0016874//ligase activity;GO:0004514//nicotinate-nucleotide diphosphorylase (carboxylating) activity;GO:0004516//nicotinate phosphoribosyltransferase activity,K00763//Nicotinate and nicotinamide metabolism;One carbon pool by folate;ABC transporters;Metabolic pathways;Folate biosynthesis
93107,0,0,0,0,0,14,0,0,14,0,0,0,"KCNG4;potassium voltage-gated channel, subfamily G, member 4",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0051260//protein homooligomerization;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0071805//potassium ion transmembrane transport,GO:0005251//delayed rectifier potassium channel activity,-
93109,58,0,0,0,0,0,0,1,7,75,0,0,TMEM44;transmembrane protein 44,GO:0016021//integral component of membrane,-,-,-
9311,0,0,0,0,0,0,0,0,0,0,9,0,ASIC3;acid-sensing (proton-gated) ion channel 3,GO:0005737//cytoplasm;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007165//signal transduction;GO:0007600//sensory perception;GO:0010447//response to acidic pH;GO:0035725//sodium ion transmembrane transport;GO:0050968//detection of chemical stimulus involved in sensory perception of pain;GO:0055085//transmembrane transport;GO:0050966//detection of mechanical stimulus involved in sensory perception of pain;GO:0050965//detection of temperature stimulus involved in sensory perception of pain;GO:0034220//ion transmembrane transport;GO:0042930//enterobactin transport;GO:0009408//response to heat;GO:0001101//response to acid chemical;GO:0050915//sensory perception of sour taste;GO:0006810//transport,GO:0042931//enterobactin transporter activity;GO:0005272//sodium channel activity;GO:0015280//ligand-gated sodium channel activity;GO:0030165//PDZ domain binding;GO:0005261//cation channel activity,-
9312,0,0,0,0,0,0,0,0,30,0,0,0,"KCNB2;potassium voltage-gated channel, Shab-related subfamily, member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0071805//potassium ion transmembrane transport;GO:0006940//regulation of smooth muscle contraction;GO:0034765//regulation of ion transmembrane transport;GO:0007268//synaptic transmission;GO:0006813//potassium ion transport;GO:0051260//protein homooligomerization,GO:0005251//delayed rectifier potassium channel activity,-
93129,54,0,0,0,0,13,12,0,21,0,5,0,ORAI3;ORAI calcium release-activated calcium modulator 3,GO:0016021//integral component of membrane,GO:0002115//store-operated calcium entry,GO:0005515//protein binding,K16058//Calcium signaling pathway
9313,114,0,0,0,0,11,0,0,8,0,7,0,MMP20;matrix metallopeptidase 20,GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0070173//regulation of enamel mineralization;GO:0006508//proteolysis;GO:0030163//protein catabolic process;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly;GO:0030574//collagen catabolic process;GO:0097186//amelogenesis,GO:0005509//calcium ion binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004222//metalloendopeptidase activity,-
93134,141,0,0,11,9,11,0,45,43,0,0,0,ZNF561;zinc finger protein 561,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
9314,0,0,1,10,41,28,0,0,7,0,0,0,KLF4;Kruppel-like factor 4 (gut),GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005730//nucleolus,"GO:0051898//negative regulation of protein kinase B signaling;GO:0071499//cellular response to laminar fluid shear stress;GO:0046985//positive regulation of hemoglobin biosynthetic process;GO:0048730//epidermis morphogenesis;GO:0019827//stem cell maintenance;GO:0045595//regulation of cell differentiation;GO:0051247//positive regulation of protein metabolic process;GO:0035166//post-embryonic hemopoiesis;GO:0032270//positive regulation of cellular protein metabolic process;GO:0045429//positive regulation of nitric oxide biosynthetic process;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0045415//negative regulation of interleukin-8 biosynthetic process;GO:0008285//negative regulation of cell proliferation;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:2000342//negative regulation of chemokine (C-X-C motif) ligand 2 production;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:0045444//fat cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0032526//response to retinoic acid;GO:0071363//cellular response to growth factor stimulus;GO:0050728//negative regulation of inflammatory response;GO:0060761//negative regulation of response to cytokine stimulus;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007500//mesodermal cell fate determination;GO:0009913//epidermal cell differentiation;GO:0031077//post-embryonic camera-type eye development;GO:0006366//transcription from RNA polymerase II promoter;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0090051//negative regulation of cell migration involved in sprouting angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:1901653//cellular response to peptide;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071409//cellular response to cycloheximide;GO:0014740//negative regulation of muscle hyperplasia;GO:0070301//cellular response to hydrogen peroxide;GO:0043551//regulation of phosphatidylinositol 3-kinase activity",GO:0001085//RNA polymerase II transcription factor binding;GO:0001010//sequence-specific DNA binding transcription factor recruiting transcription factor activity;GO:0000987//core promoter proximal region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003690//double-stranded DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0035014//phosphatidylinositol 3-kinase regulator activity;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
93145,0,0,1,0,0,27,0,73,11,0,0,0,OLFM2;olfactomedin 2,GO:0045202//synapse;GO:0005576//extracellular region;GO:0030054//cell junction;GO:0032281//alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex,GO:0009306//protein secretion,-,-
9315,0,0,0,1,1,0,0,56,13,268,3,6,NREP;neuronal regeneration related protein,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0031103//axon regeneration;GO:0017015//regulation of transforming growth factor beta receptor signaling pathway;GO:0045664//regulation of neuron differentiation,GO:0005515//protein binding,-
93164,0,0,0,0,15,0,0,0,22,0,0,0,HTR7P1;5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1,-,-,-,K04163//Neuroactive ligand-receptor interaction;Serotonergic synapse;Calcium signaling pathway
93166,0,0,0,0,0,0,11,0,23,0,9,0,PRDM6;PR domain containing 6,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0034968//histone lysine methylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0022008//neurogenesis;GO:0051151//negative regulation of smooth muscle cell differentiation",GO:0003676//nucleic acid binding;GO:0018024//histone-lysine N-methyltransferase activity;GO:0046872//metal ion binding;GO:0042803//protein homodimerization activity,K04462//MAPK signaling pathway;Pathways in cancer;Chronic myeloid leukemia
9317,0,21,0,20,51,16,1,0,32,0,0,0,PTER;phosphotriesterase related,GO:0070062//extracellular vesicular exosome,GO:0009056//catabolic process;GO:0030855//epithelial cell differentiation,"GO:0016788//hydrolase activity, acting on ester bonds;GO:0008270//zinc ion binding",-
9318,0,55,0,74,53,36,17,0,75,0,0,0,COPS2;COP9 signalosome subunit 2,GO:0008180//COP9 signalosome;GO:0005737//cytoplasm,GO:0035914//skeletal muscle cell differentiation;GO:0010388//cullin deneddylation;GO:0030182//neuron differentiation;GO:0008283//cell proliferation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0004871//signal transducer activity;GO:0005515//protein binding;GO:0003714//transcription corepressor activity,-
93183,0,0,0,1,24,38,13,0,27,0,9,0,"PIGM;phosphatidylinositol glycan anchor biosynthesis, class M",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0016254//preassembly of GPI anchor in ER membrane;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0097502//mannosylation;GO:0006501//C-terminal protein lipidation,GO:0000030//mannosyltransferase activity,K05284//Metabolic pathways;Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
93185,0,0,60,0,0,0,0,0,9,0,0,0,"IGSF8;immunoglobulin superfamily, member 8",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0007519//skeletal muscle tissue development;GO:0008283//cell proliferation;GO:0007338//single fertilization;GO:0007399//nervous system development;GO:0006928//cellular component movement,GO:0005515//protein binding,-
9319,0,0,0,0,0,24,0,0,6,226,0,0,TRIP13;thyroid hormone receptor interactor 13,GO:0005634//nucleus;GO:0001673//male germ cell nucleus,GO:0006302//double-strand break repair;GO:0007141//male meiosis I;GO:0007144//female meiosis I;GO:0007286//spermatid development;GO:2001141//regulation of RNA biosynthetic process;GO:0048477//oogenesis;GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0007130//synaptonemal complex assembly;GO:0006366//transcription from RNA polymerase II promoter;GO:0001556//oocyte maturation,GO:0005524//ATP binding;GO:0003712//transcription cofactor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K00797//Metabolic pathways;beta-Alanine metabolism;Ribosome;Cysteine and methionine metabolism;Glutathione metabolism;Arginine and proline metabolism;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K13525//Protein processing in endoplasmic reticulum;Legionellosis;K12196//Endocytosis
93190,0,0,0,0,0,1,0,0,5,0,7,0,C1orf158;chromosome 1 open reading frame 158,-,-,-,-
932,0,0,0,0,0,0,0,0,2,0,0,0,"MS4A3;membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)",GO:0012505//endomembrane system;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm,-,GO:0005515//protein binding,K08090//Asthma;Fc epsilon RI signaling pathway
9320,47,203,4,138,532,0,29,1,136,0,30,0,TRIP12;thyroid hormone receptor interactor 12,GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006974//cellular response to DNA damage stimulus;GO:2000780//negative regulation of double-strand break repair;GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:1901315//negative regulation of histone H2A K63-linked ubiquitination;GO:0009790//embryo development;GO:0006281//DNA repair,GO:0005515//protein binding;GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity;GO:0046966//thyroid hormone receptor binding,K10590//Ubiquitin mediated proteolysis
9321,0,24,1,61,113,0,11,60,78,0,6,0,TRIP11;thyroid hormone receptor interactor 11,GO:0005794//Golgi apparatus;GO:0005801//cis-Golgi network;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0002080//acrosomal membrane,GO:0003281//ventricular septum development;GO:0006366//transcription from RNA polymerase II promoter;GO:0000042//protein targeting to Golgi;GO:2001141//regulation of RNA biosynthetic process,GO:0003713//transcription coactivator activity;GO:0005515//protein binding,-
93210,0,0,1,0,0,0,14,0,24,128,0,1,PGAP3;post-GPI attachment to proteins 3,GO:0031227//intrinsic component of endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0006505//GPI anchor metabolic process;GO:0006506//GPI anchor biosynthetic process,"GO:0016788//hydrolase activity, acting on ester bonds",-
9322,97,23,0,27,36,0,22,0,42,0,10,0,TRIP10;thyroid hormone receptor interactor 10,GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0042995//cell projection;GO:0005634//nucleus;GO:0005764//lysosome;GO:0005794//Golgi apparatus;GO:0070062//extracellular vesicular exosome;GO:0001891//phagocytic cup;GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005938//cell cortex,GO:0030036//actin cytoskeleton organization;GO:0007264//small GTPase mediated signal transduction;GO:0006897//endocytosis;GO:0007154//cell communication;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007165//signal transduction,GO:0008289//lipid binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K07196//Insulin signaling pathway
93233,0,0,0,0,0,18,38,0,61,0,2,0,CCDC114;coiled-coil domain containing 114,GO:0005929//cilium;GO:0036157//outer dynein arm,GO:0036158//outer dynein arm assembly,-,K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
9324,0,0,56,13,135,0,0,0,8,0,0,0,HMGN3;high mobility group nucleosomal binding domain 3,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000785//chromatin,GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0016568//chromatin modification,GO:0031492//nucleosomal DNA binding;GO:0046966//thyroid hormone receptor binding,-
9325,0,0,1,0,15,15,0,0,40,0,0,0,TRIP4;thyroid hormone receptor interactor 4,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005815//microtubule organizing center,"GO:0006366//transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0016922//ligand-dependent nuclear receptor binding;GO:0003713//transcription coactivator activity,-
9326,0,142,26,41,33,0,0,0,31,0,100,0,"ZNHIT3;zinc finger, HIT-type containing 3",GO:0005622//intracellular,"GO:0006355//regulation of transcription, DNA-templated",GO:0046966//thyroid hormone receptor binding;GO:0046872//metal ion binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer;K01539//Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Oxidative phosphorylation;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction
93273,0,0,0,0,0,0,0,0,17,0,6,0,LEMD1;LEM domain containing 1,GO:0016021//integral component of membrane,-,-,-
9328,0,0,0,4,6,0,7,0,38,0,0,0,"GTF3C5;general transcription factor IIIC, polypeptide 5, 63kDa",GO:0005654//nucleoplasm;GO:0000127//transcription factor TFIIIC complex,"GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0010467//gene expression;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0006383//transcription from RNA polymerase III promoter;GO:0006351//transcription, DNA-templated;GO:0035914//skeletal muscle cell differentiation",GO:0003677//DNA binding;GO:0005515//protein binding,-
9329,23,69,0,11,59,0,42,69,19,0,0,0,"GTF3C4;general transcription factor IIIC, polypeptide 4, 90kDa",GO:0005654//nucleoplasm;GO:0000127//transcription factor TFIIIC complex,"GO:0010467//gene expression;GO:0042797//tRNA transcription from RNA polymerase III promoter;GO:0043085//positive regulation of catalytic activity;GO:0006351//transcription, DNA-templated;GO:0006384//transcription initiation from RNA polymerase III promoter;GO:0016573//histone acetylation;GO:0006383//transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter",GO:0005515//protein binding;GO:0004402//histone acetyltransferase activity;GO:0003677//DNA binding;GO:0008047//enzyme activator activity,-
933,0,0,0,0,0,0,27,0,3,0,10,0,CD22;CD22 molecule,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0007155//cell adhesion,GO:0005515//protein binding;GO:0030246//carbohydrate binding,K06467//Hematopoietic cell lineage;Cell adhesion molecules (CAMs);B cell receptor signaling pathway
9330,0,0,0,2,0,16,0,17,25,237,4,136,"GTF3C3;general transcription factor IIIC, polypeptide 3, 102kDa",GO:0005654//nucleoplasm;GO:0000127//transcription factor TFIIIC complex,"GO:0006351//transcription, DNA-templated;GO:0006383//transcription from RNA polymerase III promoter;GO:0042791//5S class rRNA transcription from RNA polymerase III type 1 promoter;GO:0010467//gene expression;GO:0042797//tRNA transcription from RNA polymerase III promoter",GO:0005515//protein binding;GO:0003677//DNA binding,-
9331,0,0,0,0,0,28,0,0,56,0,0,0,"B4GALT6;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6",GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0044267//cellular protein metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process,GO:0046872//metal ion binding;GO:0008378//galactosyltransferase activity,K07553//Sphingolipid metabolism;Metabolic pathways
9332,49,0,0,0,0,0,18,0,106,0,6,0,CD163;CD163 molecule,GO:0005887//integral component of plasma membrane;GO:0030666//endocytic vesicle membrane;GO:0005576//extracellular region;GO:0005886//plasma membrane,GO:0006898//receptor-mediated endocytosis;GO:0006953//acute-phase response,GO:0005044//scavenger receptor activity;GO:0005515//protein binding,-
93323,8,0,0,0,0,22,0,0,13,0,0,0,"HAUS8;HAUS augmin-like complex, subunit 8",GO:0000922//spindle pole;GO:0005874//microtubule;GO:0070652//HAUS complex;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0051225//spindle assembly;GO:0007067//mitotic nuclear division;GO:0051297//centrosome organization,-,-
9333,23,0,54,0,0,0,0,0,44,0,0,0,TGM5;transglutaminase 5,GO:0005737//cytoplasm,GO:0008544//epidermis development;GO:0006464//cellular protein modification process;GO:0018149//peptide cross-linking,GO:0003810//protein-glutamine gamma-glutamyltransferase activity;GO:0046872//metal ion binding,-
9334,81,0,0,8,11,36,29,0,13,0,0,0,"B4GALT5;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5",GO:0070062//extracellular vesicular exosome;GO:0032580//Golgi cisterna membrane;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0044267//cellular protein metabolic process;GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0018146//keratan sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0046872//metal ion binding;GO:0008378//galactosyltransferase activity,K09905//Mucin type O-Glycan biosynthesis
93349,0,0,0,7,0,34,0,0,15,0,3,0,SP140L;SP140 nuclear body protein-like,GO:0005634//nucleus,-,GO:0008270//zinc ion binding;GO:0003677//DNA binding,K15413//Herpes simplex infection
93377,0,0,0,0,0,1,0,0,10,0,0,0,OPALIN;oligodendrocytic myelin paranodal and inner loop protein,GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,-,-,-
9338,0,0,0,25,29,0,0,0,0,0,0,0,TCEAL1;transcription elongation factor A (SII)-like 1,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity,K12465//Neurotrophin signaling pathway
93380,0,0,0,9,30,4,12,0,25,0,0,0,MMGT1;membrane magnesium transporter 1,GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0031901//early endosome membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0072546//ER membrane protein complex,GO:0015693//magnesium ion transport,GO:0015095//magnesium ion transmembrane transporter activity,-
9340,11,0,0,0,0,20,35,0,59,0,6,0,GLP2R;glucagon-like peptide 2 receptor,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0008284//positive regulation of cell proliferation;GO:0071377//cellular response to glucagon stimulus;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway,GO:0004967//glucagon receptor activity;GO:0004930//G-protein coupled receptor activity,K04582//Neuroactive ligand-receptor interaction
93408,0,0,0,0,0,4,13,0,14,0,0,0,"MYL10;myosin, light chain 10, regulatory",GO:0005739//mitochondrion,-,GO:0005509//calcium ion binding,K12756//Regulation of actin cytoskeleton;Tight junction;Focal adhesion;Leukocyte transendothelial migration
9341,0,6,2,19,70,0,0,0,1,0,13,0,VAMP3;vesicle-associated membrane protein 3,GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0030136//clathrin-coated vesicle;GO:0009986//cell surface;GO:0030054//cell junction;GO:0045202//synapse;GO:0031201//SNARE complex;GO:0005886//plasma membrane;GO:0030665//clathrin-coated vesicle membrane;GO:0016324//apical plasma membrane;GO:0030141//secretory granule;GO:0055037//recycling endosome,"GO:0006904//vesicle docking involved in exocytosis;GO:0001921//positive regulation of receptor recycling;GO:0035493//SNARE complex assembly;GO:0061025//membrane fusion;GO:0017156//calcium ion-dependent exocytosis;GO:0006887//exocytosis;GO:0034446//substrate adhesion-dependent cell spreading;GO:0042147//retrograde transport, endosome to Golgi;GO:0016192//vesicle-mediated transport;GO:0043001//Golgi to plasma membrane protein transport;GO:0006461//protein complex assembly",GO:0005515//protein binding;GO:0017075//syntaxin-1 binding,K13505//SNARE interactions in vesicular transport;Phagosome
9342,0,0,0,8,59,0,0,10,3,0,16,0,"SNAP29;synaptosomal-associated protein, 29kDa",GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0045202//synapse;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0031201//SNARE complex;GO:0043005//neuron projection,GO:0006903//vesicle targeting;GO:0006887//exocytosis;GO:0000046//autophagic vacuole fusion;GO:0061025//membrane fusion;GO:0015031//protein transport,GO:0005484//SNAP receptor activity,K08509//SNARE interactions in vesicular transport
93426,0,0,0,0,0,29,0,0,19,0,0,0,SYCE1;synaptonemal complex central element protein 1,GO:0000801//central element,GO:0007130//synaptonemal complex assembly,-,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction
93429,98,0,0,0,0,0,0,0,0,0,0,0,DKFZp434J0226;uncharacterized LOC93429,-,-,-,-
9343,53,0,0,29,37,0,15,3,19,0,0,0,EFTUD2;elongation factor Tu GTP binding domain containing 2,GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005681//spliceosomal complex;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005730//nucleolus;GO:0015030//Cajal body;GO:0005634//nucleus,"GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006397//mRNA processing;GO:0000398//mRNA splicing, via spliceosome;GO:0006184//GTP catabolic process",GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12852//Spliceosome
93432,0,0,0,0,0,30,33,1,86,0,7,0,LOC93432;maltase-glucoamylase (alpha-glucosidase),-,-,-,K12047//Metabolic pathways;Galactose metabolism;Starch and sucrose metabolism;Carbohydrate digestion and absorption
93436,0,31,0,9,1,0,0,0,0,0,0,0,ARMC6;armadillo repeat containing 6,-,GO:0002244//hematopoietic progenitor cell differentiation,-,K08844//Parkinson's disease
9344,15,0,1,11,17,20,41,2,41,120,0,0,TAOK2;TAO kinase 2,GO:0030425//dendrite;GO:0016021//integral component of membrane;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0043235//receptor complex,GO:0006915//apoptotic process;GO:0030036//actin cytoskeleton organization;GO:0000186//activation of MAPKK activity;GO:0046330//positive regulation of JNK cascade;GO:0051403//stress-activated MAPK cascade;GO:0006468//protein phosphorylation;GO:0006950//response to stress;GO:0008360//regulation of cell shape;GO:0001558//regulation of cell growth;GO:0032874//positive regulation of stress-activated MAPK cascade;GO:0006974//cellular response to DNA damage stimulus;GO:0048041//focal adhesion assembly;GO:0016477//cell migration;GO:0031572//G2 DNA damage checkpoint;GO:0006612//protein targeting to membrane,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0031434//mitogen-activated protein kinase kinase binding,K04429//MAPK signaling pathway
93474,0,0,0,0,2,0,66,0,34,0,3,0,ZNF670;zinc finger protein 670,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
9348,0,0,0,14,0,0,0,0,64,0,12,0,NDST3;N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030210//heparin biosynthetic process;GO:0015012//heparan sulfate proteoglycan biosynthetic process,GO:0019213//deacetylase activity;GO:0015016//[heparan sulfate]-glucosamine N-sulfotransferase activity,K02578//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
93487,0,1,0,21,135,0,3,0,19,0,0,0,MAPK1IP1L;mitogen-activated protein kinase 1 interacting protein 1-like,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
9349,0,118,0,145,355,0,0,0,13,0,0,0,RPL23;ribosomal protein L23,GO:0005840//ribosome;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0022625//cytosolic large ribosomal subunit;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome,"GO:0044267//cellular protein metabolic process;GO:0010467//gene expression;GO:0006412//translation;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006413//translational initiation;GO:0019083//viral transcription;GO:0016070//RNA metabolic process;GO:0006610//ribosomal protein import into nucleus;GO:0006415//translational termination;GO:0019058//viral life cycle;GO:0016071//mRNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006414//translational elongation;GO:0016032//viral process",GO:0003735//structural constituent of ribosome;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K02894//Ribosome
93492,0,0,0,0,0,0,36,1,50,0,0,0,TPTE2;transmembrane phosphoinositide 3-phosphatase and tensin homolog 2,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006661//phosphatidylinositol biosynthetic process;GO:0034220//ion transmembrane transport;GO:0006644//phospholipid metabolic process;GO:0035335//peptidyl-tyrosine dephosphorylation,"GO:0016314//phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0004725//protein tyrosine phosphatase activity;GO:0008138//protein tyrosine/serine/threonine phosphatase activity;GO:0005216//ion channel activity",K01110//Phosphatidylinositol signaling system;Pathways in cancer;Tight junction;Small cell lung cancer;Prostate cancer;Melanoma;Endometrial cancer;Inositol phosphate metabolism;Focal adhesion;p53 signaling pathway;Glioma
9350,0,0,0,0,0,0,0,36,0,0,0,0,"CER1;cerberus 1, DAN family BMP antagonist",GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0030282//bone mineralization;GO:0007399//nervous system development;GO:0032926//negative regulation of activin receptor signaling pathway;GO:0035582//sequestering of BMP in extracellular matrix;GO:0048263//determination of dorsal identity;GO:0030514//negative regulation of BMP signaling pathway;GO:0009948//anterior/posterior axis specification;GO:0001657//ureteric bud development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0042074//cell migration involved in gastrulation;GO:0009952//anterior/posterior pattern specification;GO:0007369//gastrulation;GO:0008285//negative regulation of cell proliferation;GO:0030509//BMP signaling pathway;GO:0023019//signal transduction involved in regulation of gene expression;GO:2000381//negative regulation of mesoderm development;GO:0003419//growth plate cartilage chondrocyte proliferation;GO:0071773//cellular response to BMP stimulus,GO:0036122//BMP binding;GO:0042803//protein homodimerization activity;GO:0005125//cytokine activity;GO:0016015//morphogen activity,K01645//Wnt signaling pathway
9351,0,1,0,9,33,9,1,0,10,0,0,355,"SLC9A3R2;solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0012505//endomembrane system;GO:0005925//focal adhesion;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0005634//nucleus,GO:0006461//protein complex assembly;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling,GO:0008013//beta-catenin binding;GO:0005102//receptor binding;GO:0008022//protein C-terminus binding;GO:0005515//protein binding;GO:0019902//phosphatase binding,K13358//Aldosterone-regulated sodium reabsorption
93517,23,0,0,0,17,1,19,0,15,0,0,0,"SDR42E1;short chain dehydrogenase/reductase family 42E, member 1",GO:0016021//integral component of membrane,GO:0055114//oxidation-reduction process;GO:0006694//steroid biosynthetic process,GO:0003854//3-beta-hydroxy-delta5-steroid dehydrogenase activity,K07748//Metabolic pathways;Steroid biosynthesis
9352,0,15,1,4,46,5,0,0,0,0,4,0,TXNL1;thioredoxin-like 1,GO:0070062//extracellular vesicular exosome;GO:0000502//proteasome complex;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0045454//cell redox homeostasis;GO:0006662//glycerol ether metabolic process;GO:0055114//oxidation-reduction process,GO:0015035//protein disulfide oxidoreductase activity;GO:0015036//disulfide oxidoreductase activity,K03671//Selenocompound metabolism;Pyrimidine metabolism
9353,2,0,0,0,0,7,47,0,105,0,11,0,SLIT2;slit homolog 2 (Drosophila),GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016020//membrane;GO:0009986//cell surface,GO:0061364//apoptotic process involved in luteolysis;GO:0030308//negative regulation of cell growth;GO:0030336//negative regulation of cell migration;GO:0016337//single organismal cell-cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0008045//motor neuron axon guidance;GO:0043116//negative regulation of vascular permeability;GO:0001933//negative regulation of protein phosphorylation;GO:0048754//branching morphogenesis of an epithelial tube;GO:0031290//retinal ganglion cell axon guidance;GO:0021972//corticospinal neuron axon guidance through spinal cord;GO:0030837//negative regulation of actin filament polymerization;GO:0010629//negative regulation of gene expression;GO:0051058//negative regulation of small GTPase mediated signal transduction;GO:0070100//negative regulation of chemokine-mediated signaling pathway;GO:0010596//negative regulation of endothelial cell migration;GO:0060763//mammary duct terminal end bud growth;GO:0050919//negative chemotaxis;GO:0090027//negative regulation of monocyte chemotaxis;GO:0043086//negative regulation of catalytic activity;GO:0071672//negative regulation of smooth muscle cell chemotaxis;GO:0071504//cellular response to heparin;GO:0014912//negative regulation of smooth muscle cell migration;GO:0007411//axon guidance;GO:0002042//cell migration involved in sprouting angiogenesis;GO:0035385//Roundabout signaling pathway;GO:0001656//metanephros development;GO:0021834//chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration;GO:0030517//negative regulation of axon extension;GO:0001701//in utero embryonic development;GO:0050929//induction of negative chemotaxis;GO:0043065//positive regulation of apoptotic process;GO:0021836//chemorepulsion involved in postnatal olfactory bulb interneuron migration;GO:0048846//axon extension involved in axon guidance;GO:0010593//negative regulation of lamellipodium assembly;GO:0090260//negative regulation of retinal ganglion cell axon guidance;GO:0001657//ureteric bud development;GO:0033563//dorsal/ventral axon guidance;GO:0051414//response to cortisol;GO:0071676//negative regulation of mononuclear cell migration;GO:0050772//positive regulation of axonogenesis;GO:0032870//cellular response to hormone stimulus;GO:0090024//negative regulation of neutrophil chemotaxis;GO:0090288//negative regulation of cellular response to growth factor stimulus,GO:0042802//identical protein binding;GO:0048495//Roundabout binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0008201//heparin binding;GO:0043394//proteoglycan binding;GO:0005509//calcium ion binding;GO:0005095//GTPase inhibitor activity;GO:0043237//laminin-1 binding;GO:0045499//chemorepellent activity,K06839//Axon guidance
9354,2,0,0,15,12,53,10,51,46,8,0,3,UBE4A;ubiquitination factor E4A,GO:0000151//ubiquitin ligase complex;GO:0005737//cytoplasm,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination,GO:0005515//protein binding;GO:0034450//ubiquitin-ubiquitin ligase activity,K10596//Ubiquitin mediated proteolysis
9355,0,0,0,0,9,0,1,0,8,0,0,291,LHX2;LIM homeobox 2,GO:0005634//nucleus,"GO:0048675//axon extension;GO:0009953//dorsal/ventral pattern formation;GO:0021987//cerebral cortex development;GO:0021772//olfactory bulb development;GO:2000678//negative regulation of transcription regulatory region DNA binding;GO:0006366//transcription from RNA polymerase II promoter;GO:0007411//axon guidance;GO:0007498//mesoderm development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060041//retina development in camera-type eye;GO:0021978//telencephalon regionalization;GO:0001843//neural tube closure",GO:0003682//chromatin binding;GO:0008270//zinc ion binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0043565//sequence-specific DNA binding,-
93550,0,0,0,0,7,0,0,0,42,0,0,0,"ZFAND4;zinc finger, AN1-type domain 4",-,-,GO:0008270//zinc ion binding,-
93556,0,0,0,0,0,0,0,0,40,0,0,0,"EGFEM1P;EGF-like and EMI domain containing 1, pseudogene",-,-,-,-
9356,0,0,0,0,0,31,0,0,23,0,0,0,"SLC22A6;solute carrier family 22 (organic anion transporter), member 6",GO:0005887//integral component of plasma membrane;GO:0043234//protein complex;GO:0005901//caveola;GO:0016323//basolateral plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0097254//renal tubular secretion;GO:0015742//alpha-ketoglutarate transport;GO:0034220//ion transmembrane transport;GO:0043252//sodium-independent organic anion transport;GO:0055085//transmembrane transport;GO:0015711//organic anion transport;GO:0051260//protein homooligomerization;GO:0031427//response to methotrexate,GO:0042803//protein homodimerization activity;GO:0005452//inorganic anion exchanger activity;GO:0005515//protein binding;GO:0015347//sodium-independent organic anion transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity;GO:0031404//chloride ion binding,-
9358,0,0,0,0,0,18,12,145,42,4,0,1,"ITGBL1;integrin, beta-like 1 (with EGF-like repeat domains)",GO:0005576//extracellular region,GO:0007155//cell adhesion,-,K06493//Focal adhesion;Hematopoietic cell lineage;ECM-receptor interaction;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Osteoclast differentiation;Dilated cardiomyopathy;Phagosome;Arrhythmogenic right ventricular cardiomyopathy (ARVC)
93587,0,0,0,0,11,0,0,0,14,0,0,0,TRMT10A;tRNA methyltransferase 10 homolog A (S. cerevisiae),GO:0070062//extracellular vesicular exosome,GO:0032259//methylation;GO:0010960//magnesium ion homeostasis,GO:0044822//poly(A) RNA binding;GO:0008168//methyltransferase activity,-
93589,0,0,0,0,15,13,70,57,92,1,19,0,"CACNA2D4;calcium channel, voltage-dependent, alpha 2/delta subunit 4",GO:0005891//voltage-gated calcium channel complex,GO:0050908//detection of light stimulus involved in visual perception;GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport,GO:0005245//voltage-gated calcium channel activity;GO:0046872//metal ion binding,K04861//Arrhythmogenic right ventricular cardiomyopathy (ARVC);Hypertrophic cardiomyopathy (HCM);MAPK signaling pathway;Cardiac muscle contraction;Dilated cardiomyopathy
93594,0,0,0,0,10,11,13,0,7,0,16,0,"TBC1D31;TBC1 domain family, member 31",GO:0005813//centrosome,GO:0032851//positive regulation of Rab GTPase activity,GO:0005097//Rab GTPase activator activity,K01062//Metabolic pathways;Biosynthesis of secondary metabolites;Ether lipid metabolism
9360,87,0,0,11,67,7,0,0,25,11,0,1,PPIG;peptidylprolyl isomerase G (cyclophilin G),GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016363//nuclear matrix;GO:0005654//nucleoplasm,GO:0006457//protein folding;GO:0000413//protein peptidyl-prolyl isomerization;GO:0008380//RNA splicing,GO:0016018//cyclosporin A binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003755//peptidyl-prolyl cis-trans isomerase activity,-
9361,145,69,30,36,89,0,46,181,38,0,38,0,"LONP1;lon peptidase 1, mitochondrial",GO:0016020//membrane;GO:0005739//mitochondrion;GO:0042645//mitochondrial nucleoid;GO:0005759//mitochondrial matrix;GO:0005737//cytoplasm,GO:0051131//chaperone-mediated protein complex assembly;GO:0001666//response to hypoxia;GO:0051603//proteolysis involved in cellular protein catabolic process;GO:0090296//regulation of mitochondrial DNA replication;GO:0010044//response to aluminum ion;GO:0070407//oxidation-dependent protein catabolic process;GO:0007568//aging;GO:0034599//cellular response to oxidative stress;GO:0051260//protein homooligomerization;GO:0000002//mitochondrial genome maintenance;GO:0006200//ATP catabolic process;GO:0009725//response to hormone;GO:0006515//misfolded or incompletely synthesized protein catabolic process;GO:0007005//mitochondrion organization,GO:0070182//DNA polymerase binding;GO:0003727//single-stranded RNA binding;GO:0003697//single-stranded DNA binding;GO:0070363//mitochondrial light strand promoter sense binding;GO:0043565//sequence-specific DNA binding;GO:0070362//mitochondrial heavy strand promoter anti-sense binding;GO:0004176//ATP-dependent peptidase activity;GO:0005524//ATP binding;GO:0004252//serine-type endopeptidase activity;GO:0005515//protein binding;GO:0051880//G-quadruplex DNA binding;GO:0070361//mitochondrial light strand promoter anti-sense binding;GO:0043531//ADP binding;GO:0070364//mitochondrial heavy strand promoter sense binding,-
93611,0,10,3,0,9,26,41,37,44,0,58,0,FBXO44;F-box protein 44,GO:0019005//SCF ubiquitin ligase complex,-,GO:0005515//protein binding,-
9362,0,0,0,0,0,0,49,114,78,0,0,0,CPNE6;copine VI (neuronal),GO:0030424//axon;GO:0030425//dendrite;GO:0070062//extracellular vesicular exosome;GO:0016020//membrane,GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0006629//lipid metabolic process;GO:0016192//vesicle-mediated transport,GO:0005215//transporter activity;GO:0005509//calcium ion binding;GO:0001786//phosphatidylserine binding,K06491//Cell adhesion molecules (CAMs);Prion diseases
93621,2,135,3,162,464,9,0,56,11,0,0,0,MRFAP1;Morf4 family associated protein 1,GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,-,GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K11447//Transcriptional misregulation in cancer
93624,0,0,0,19,36,0,1,0,44,0,16,0,TADA2B;transcriptional adaptor 2B,GO:0070461//SAGA-type complex;GO:0030914//STAGA complex,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0006325//chromatin organization",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
93627,0,202,61,97,190,24,0,0,92,0,64,0,TBCK;TBC1 domain containing kinase,-,GO:0006468//protein phosphorylation;GO:0032851//positive regulation of Rab GTPase activity,GO:0004672//protein kinase activity;GO:0005097//Rab GTPase activator activity;GO:0005524//ATP binding,K15014//Alcoholism;K07198//Hypertrophic cardiomyopathy (HCM);Adipocytokine signaling pathway;Regulation of autophagy;mTOR signaling pathway;Insulin signaling pathway;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K02091//Cell cycle;Measles;p53 signaling pathway;Glioma;Chronic myeloid leukemia;Melanoma;Non-small cell lung cancer;Small cell lung cancer;Pancreatic cancer;Pathways in cancer
9363,0,0,0,0,0,18,0,0,0,0,0,0,"RAB33A;RAB33A, member RAS oncogene family",GO:0005886//plasma membrane,GO:0019882//antigen processing and presentation;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0005515//protein binding,-
9364,0,0,0,18,10,10,63,0,35,0,0,0,"RAB28;RAB28, member RAS oncogene family",GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0036064//ciliary basal body;GO:0005886//plasma membrane,GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0019003//GDP binding,-
93643,0,0,0,0,8,14,0,0,27,0,7,0,TJAP1;tight junction associated protein 1 (peripheral),GO:0005802//trans-Golgi network;GO:0005634//nucleus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005923//tight junction;GO:0005768//endosome;GO:0005794//Golgi apparatus,GO:0007030//Golgi organization,GO:0005515//protein binding,K06105//Tight junction
93649,0,26,1,0,0,0,0,6,53,0,9,0,MYOCD;myocardin,GO:0005634//nucleus,"GO:0051152//positive regulation of smooth muscle cell differentiation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0060065//uterus development;GO:0045987//positive regulation of smooth muscle contraction;GO:0048286//lung alveolus development;GO:0003231//cardiac ventricle development;GO:0071456//cellular response to hypoxia;GO:2000727//positive regulation of cardiac muscle cell differentiation;GO:0001570//vasculogenesis;GO:0060157//urinary bladder development;GO:0001666//response to hypoxia;GO:0045736//negative regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0055007//cardiac muscle cell differentiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0071363//cellular response to growth factor stimulus;GO:0045661//regulation of myoblast differentiation;GO:0035051//cardiocyte differentiation;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:2001015//negative regulation of skeletal muscle cell differentiation;GO:0035065//regulation of histone acetylation;GO:2000724//positive regulation of cardiac vascular smooth muscle cell differentiation;GO:0097070//ductus arteriosus closure;GO:0061049//cell growth involved in cardiac muscle cell development;GO:0043388//positive regulation of DNA binding;GO:0001560//regulation of cell growth by extracellular stimulus;GO:1900222//negative regulation of beta-amyloid clearance;GO:0008285//negative regulation of cell proliferation;GO:0010832//negative regulation of myotube differentiation;GO:0055012//ventricular cardiac muscle cell differentiation;GO:0008284//positive regulation of cell proliferation;GO:0048565//digestive tract development;GO:2000721//positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0030511//positive regulation of transforming growth factor beta receptor signaling pathway;GO:0051150//regulation of smooth muscle cell differentiation;GO:0003257//positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation;GO:0051145//smooth muscle cell differentiation",GO:0001046//core promoter sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0001076//RNA polymerase II transcription factor binding transcription factor activity;GO:0003713//transcription coactivator activity;GO:0019904//protein domain specific binding;GO:0070412//R-SMAD binding;GO:0035035//histone acetyltransferase binding;GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,-
9365,0,50,0,4,37,46,0,0,17,0,8,0,KL;klotho,GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0005887//integral component of plasma membrane,GO:0090080//positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0006112//energy reserve metabolic process;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0030501//positive regulation of bone mineralization;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0002526//acute inflammatory response;GO:0005975//carbohydrate metabolic process;GO:0055074//calcium ion homeostasis;GO:0045087//innate immune response;GO:0007568//aging,GO:0005104//fibroblast growth factor receptor binding;GO:0008422//beta-glucosidase activity;GO:0005179//hormone activity;GO:0005499//vitamin D binding;GO:0004566//beta-glucuronidase activity;GO:0004871//signal transducer activity;GO:0017134//fibroblast growth factor binding,K14756//Starch and sucrose metabolism;Endocrine and other factor-regulated calcium reabsorption;Pentose and glucuronate interconversions;Metabolic pathways
93650,0,0,0,14,0,0,8,3,11,0,0,0,"ACPT;acid phosphatase, testicular",GO:0016021//integral component of membrane,GO:0016311//dephosphorylation,GO:0003993//acid phosphatase activity,K14410//Riboflavin metabolism;Lysosome
93653,0,0,10,32,156,0,0,2,20,0,89,178,ST7-AS1;ST7 antisense RNA 1,-,-,-,-
93655,0,0,0,0,0,0,0,0,5,0,0,0,ST7-OT3;ST7 overlapping transcript 3,-,-,-,-
93663,0,2,0,29,120,0,54,28,28,0,0,0,ARHGAP18;Rho GTPase activating protein 18,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K08773//Pathways in cancer;Pancreatic cancer
93664,21,21,1,31,127,22,25,40,74,1,13,135,CADPS2;Ca++-dependent secretion activator 2,GO:0030659//cytoplasmic vesicle membrane;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane,GO:0016082//synaptic vesicle priming;GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport;GO:0009267//cellular response to starvation,GO:0046872//metal ion binding;GO:0008289//lipid binding,-
9367,0,0,0,12,13,0,0,0,18,0,0,0,"RAB9A;RAB9A, member RAS oncogene family",GO:0005764//lysosome;GO:0005789//endoplasmic reticulum membrane;GO:0005770//late endosome;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0030670//phagocytic vesicle membrane;GO:0045335//phagocytic vesicle,GO:0045921//positive regulation of exocytosis;GO:0015031//protein transport;GO:0007264//small GTPase mediated signal transduction;GO:0006184//GTP catabolic process,GO:0019003//GDP binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,K07899//Measles
9368,0,1,0,4,11,0,20,0,0,0,0,0,"SLC9A3R1;solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1",GO:0015629//actin cytoskeleton;GO:0031528//microvillus membrane;GO:0016324//apical plasma membrane;GO:0031982//vesicle;GO:0005813//centrosome;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0005634//nucleus;GO:0071944//cell periphery;GO:0043231//intracellular membrane-bounded organelle;GO:0097225//sperm midpiece;GO:0005902//microvillus;GO:0005737//cytoplasm;GO:0001726//ruffle;GO:0016020//membrane;GO:0031526//brush border membrane;GO:0030175//filopodium;GO:0070062//extracellular vesicular exosome;GO:0012505//endomembrane system,GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0030643//cellular phosphate ion homeostasis;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0030036//actin cytoskeleton organization;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0007191//adenylate cyclase-activating dopamine receptor signaling pathway;GO:0006461//protein complex assembly;GO:0034613//cellular protein localization;GO:0045859//regulation of protein kinase activity;GO:0016055//Wnt signaling pathway;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0070293//renal absorption;GO:0032416//negative regulation of sodium:proton antiporter activity;GO:0034635//glutathione transport;GO:0044062//regulation of excretion;GO:0032782//bile acid secretion;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0003096//renal sodium ion transport;GO:0010766//negative regulation of sodium ion transport;GO:0097291//renal phosphate ion absorption;GO:0051898//negative regulation of protein kinase B signaling;GO:0030033//microvillus assembly,GO:0005102//receptor binding;GO:0032947//protein complex scaffold;GO:0031698//beta-2 adrenergic receptor binding;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0043621//protein self-association;GO:0019902//phosphatase binding;GO:0070851//growth factor receptor binding;GO:0008013//beta-catenin binding;GO:0017081//chloride channel regulator activity;GO:0032403//protein complex binding;GO:0050780//dopamine receptor binding,-
9369,105,0,0,11,0,18,0,17,120,159,10,289,NRXN3;neurexin 3,GO:0016021//integral component of membrane;GO:0005887//integral component of plasma membrane,GO:0007416//synapse assembly;GO:0090129//positive regulation of synapse maturation;GO:0007158//neuron cell-cell adhesion;GO:0071625//vocalization behavior;GO:0051965//positive regulation of synapse assembly;GO:0001525//angiogenesis;GO:0030534//adult behavior;GO:0035176//social behavior;GO:0007269//neurotransmitter secretion;GO:0007411//axon guidance;GO:0007612//learning,GO:0005246//calcium channel regulator activity;GO:0004872//receptor activity;GO:0050839//cell adhesion molecule binding;GO:0097109//neuroligin family protein binding;GO:0046872//metal ion binding,K07377//Cell adhesion molecules (CAMs)
9370,0,0,0,0,0,0,0,0,41,319,48,0,"ADIPOQ;adiponectin, C1Q and collagen domain containing",GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005581//collagen trimer,"GO:0045776//negative regulation of blood pressure;GO:0071639//positive regulation of monocyte chemotactic protein-1 production;GO:0006006//glucose metabolic process;GO:0010875//positive regulation of cholesterol efflux;GO:0034383//low-density lipoprotein particle clearance;GO:0050728//negative regulation of inflammatory response;GO:0043407//negative regulation of MAP kinase activity;GO:0001666//response to hypoxia;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0007584//response to nutrient;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0009967//positive regulation of signal transduction;GO:0030853//negative regulation of granulocyte differentiation;GO:0045471//response to ethanol;GO:2000534//positive regulation of renal albumin absorption;GO:0045777//positive regulation of blood pressure;GO:0035690//cellular response to drug;GO:0072659//protein localization to plasma membrane;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:0070994//detection of oxidative stress;GO:0045715//negative regulation of low-density lipoprotein particle receptor biosynthetic process;GO:0007623//circadian rhythm;GO:0010906//regulation of glucose metabolic process;GO:0032757//positive regulation of interleukin-8 production;GO:0001934//positive regulation of protein phosphorylation;GO:0045650//negative regulation of macrophage differentiation;GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:0070208//protein heterotrimerization;GO:0032270//positive regulation of cellular protein metabolic process;GO:0043124//negative regulation of I-kappaB kinase/NF-kappaB signaling;GO:0033034//positive regulation of myeloid cell apoptotic process;GO:0009749//response to glucose;GO:0009744//response to sucrose;GO:0014823//response to activity;GO:0030336//negative regulation of cell migration;GO:0006635//fatty acid beta-oxidation;GO:2000584//negative regulation of platelet-derived growth factor receptor-alpha signaling pathway;GO:0050765//negative regulation of phagocytosis;GO:0071872//cellular response to epinephrine stimulus;GO:0006091//generation of precursor metabolites and energy;GO:0010642//negative regulation of platelet-derived growth factor receptor signaling pathway;GO:0032869//cellular response to insulin stimulus;GO:0010739//positive regulation of protein kinase A signaling;GO:0034115//negative regulation of heterotypic cell-cell adhesion;GO:2000590//negative regulation of metanephric mesenchymal cell migration;GO:0045892//negative regulation of transcription, DNA-templated;GO:0046888//negative regulation of hormone secretion;GO:0045721//negative regulation of gluconeogenesis;GO:2000478//positive regulation of metanephric glomerular visceral epithelial cell development;GO:0050873//brown fat cell differentiation;GO:0034612//response to tumor necrosis factor;GO:0051384//response to glucocorticoid;GO:2000279//negative regulation of DNA biosynthetic process;GO:0051260//protein homooligomerization;GO:0019395//fatty acid oxidation;GO:0045923//positive regulation of fatty acid metabolic process;GO:0045599//negative regulation of fat cell differentiation;GO:0014912//negative regulation of smooth muscle cell migration;GO:1900121//negative regulation of receptor binding;GO:0090317//negative regulation of intracellular protein transport;GO:0051899//membrane depolarization;GO:0031953//negative regulation of protein autophosphorylation;GO:0071320//cellular response to cAMP;GO:0032720//negative regulation of tumor necrosis factor production;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0033211//adiponectin-activated signaling pathway;GO:0060081//membrane hyperpolarization;GO:0042593//glucose homeostasis;GO:0070543//response to linoleic acid;GO:0010804//negative regulation of tumor necrosis factor-mediated signaling pathway;GO:0046326//positive regulation of glucose import;GO:0070373//negative regulation of ERK1 and ERK2 cascade;GO:0050805//negative regulation of synaptic transmission",GO:0005102//receptor binding;GO:0042803//protein homodimerization activity;GO:0005179//hormone activity;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0005125//cytokine activity;GO:0033691//sialic acid binding,K07296//Type II diabetes mellitus;Adipocytokine signaling pathway;PPAR signaling pathway
9371,76,2,0,19,85,36,0,0,19,58,10,0,KIF3B;kinesin family member 3B,GO:0005829//cytosol;GO:0005929//cilium;GO:0030496//midbody;GO:0016939//kinesin II complex;GO:0005876//spindle microtubule;GO:0015630//microtubule cytoskeleton;GO:0030990//intraciliary transport particle;GO:0005873//plus-end kinesin complex;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005813//centrosome,GO:0007018//microtubule-based movement;GO:0072383//plus-end-directed vesicle transport along microtubule;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0006200//ATP catabolic process;GO:0007368//determination of left/right symmetry;GO:0008089//anterograde axon cargo transport;GO:0007100//mitotic centrosome separation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation;GO:0090307//spindle assembly involved in mitosis;GO:0061024//membrane organization;GO:0008152//metabolic process;GO:0007052//mitotic spindle organization,GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0005515//protein binding;GO:0017048//Rho GTPase binding;GO:0016887//ATPase activity;GO:0008574//plus-end-directed microtubule motor activity;GO:0005524//ATP binding,-
9372,0,1,0,27,116,21,0,0,47,0,16,0,"ZFYVE9;zinc finger, FYVE domain containing 9",GO:0005769//early endosome;GO:0031901//early endosome membrane,GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006508//proteolysis;GO:0007184//SMAD protein import into nucleus;GO:0006897//endocytosis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0007183//SMAD protein complex assembly,GO:0008236//serine-type peptidase activity;GO:0005545//1-phosphatidylinositol binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K04679//TGF-beta signaling pathway;Endocytosis
9373,0,71,0,28,46,0,0,0,14,0,0,0,PLAA;phospholipase A2-activating protein,GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0043085//positive regulation of catalytic activity;GO:0006644//phospholipid metabolic process;GO:0006954//inflammatory response,GO:0005515//protein binding;GO:0016005//phospholipase A2 activator activity,K14018//Protein processing in endoplasmic reticulum
9375,0,0,0,6,31,0,18,0,18,0,0,0,TM9SF2;transmembrane 9 superfamily member 2,GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0010008//endosome membrane;GO:0005887//integral component of plasma membrane,GO:0006810//transport,-,-
9376,0,0,0,0,0,34,0,0,16,0,5,0,"SLC22A8;solute carrier family 22 (organic anion transporter), member 8",GO:0016323//basolateral plasma membrane;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0009636//response to toxic substance;GO:0034635//glutathione transport;GO:0055085//transmembrane transport;GO:0015697//quaternary ammonium group transport;GO:0034220//ion transmembrane transport;GO:0031427//response to methotrexate,GO:0005452//inorganic anion exchanger activity;GO:0005080//protein kinase C binding;GO:0015651//quaternary ammonium group transmembrane transporter activity;GO:0008514//organic anion transmembrane transporter activity,K08205//Bile secretion
9377,0,0,0,8,3,0,0,0,0,0,0,0,COX5A;cytochrome c oxidase subunit Va,GO:0005743//mitochondrial inner membrane;GO:0070062//extracellular vesicular exosome,GO:0044237//cellular metabolic process;GO:0044281//small molecule metabolic process;GO:1902600//hydrogen ion transmembrane transport;GO:0022904//respiratory electron transport chain,GO:0004129//cytochrome-c oxidase activity;GO:0009055//electron carrier activity;GO:0046872//metal ion binding,K02264//Cardiac muscle contraction;Metabolic pathways;Parkinson's disease;Huntington's disease;Alzheimer's disease;Oxidative phosphorylation
9378,124,0,0,0,19,25,25,0,125,1,2,111,NRXN1;neurexin 1,GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0042734//presynaptic membrane;GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0044295//axonal growth cone;GO:0030139//endocytic vesicle;GO:0005887//integral component of plasma membrane,"GO:0045184//establishment of protein localization;GO:0035176//social behavior;GO:0023041//neuronal signal transduction;GO:0007157//heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0097120//receptor localization to synapse;GO:0007416//synapse assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0097104//postsynaptic membrane assembly;GO:2000463//positive regulation of excitatory postsynaptic membrane potential;GO:0097117//guanylate kinase-associated protein clustering;GO:0035418//protein localization to synapse;GO:0007269//neurotransmitter secretion;GO:0007158//neuron cell-cell adhesion;GO:0001525//angiogenesis;GO:0097114//N-methyl-D-aspartate receptor clustering;GO:0030534//adult behavior;GO:0097112//gamma-aminobutyric acid receptor clustering;GO:0090004//positive regulation of establishment of protein localization to plasma membrane;GO:0051968//positive regulation of synaptic transmission, glutamatergic;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0021707//cerebellar granule cell differentiation;GO:0007268//synaptic transmission;GO:0097116//gephyrin clustering;GO:0042551//neuron maturation;GO:0051965//positive regulation of synapse assembly;GO:2000310//regulation of N-methyl-D-aspartate selective glutamate receptor activity;GO:2000311//regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity;GO:0097105//presynaptic membrane assembly;GO:0051490//negative regulation of filopodium assembly;GO:0050885//neuromuscular process controlling balance;GO:0007612//learning;GO:0007411//axon guidance;GO:0090129//positive regulation of synapse maturation;GO:0097091//synaptic vesicle clustering;GO:0030198//extracellular matrix organization;GO:0042297//vocal learning;GO:0097118//neuroligin clustering;GO:0071625//vocalization behavior",GO:0005246//calcium channel regulator activity;GO:0004872//receptor activity;GO:0097109//neuroligin family protein binding;GO:0050839//cell adhesion molecule binding;GO:0033130//acetylcholine receptor binding;GO:0005102//receptor binding;GO:0005509//calcium ion binding;GO:0048306//calcium-dependent protein binding;GO:0005515//protein binding;GO:0046872//metal ion binding,K07377//Cell adhesion molecules (CAMs)
9379,27,0,58,1,0,16,16,0,31,0,11,0,NRXN2;neurexin 2,GO:0016021//integral component of membrane,GO:0035176//social behavior;GO:0030534//adult behavior;GO:0007268//synaptic transmission;GO:0007269//neurotransmitter secretion;GO:0097116//gephyrin clustering;GO:0007158//neuron cell-cell adhesion;GO:0007416//synapse assembly;GO:0097119//postsynaptic density protein 95 clustering;GO:0042297//vocal learning;GO:0097118//neuroligin clustering;GO:0097104//postsynaptic membrane assembly;GO:0071625//vocalization behavior,GO:0005246//calcium channel regulator activity;GO:0050839//cell adhesion molecule binding;GO:0097109//neuroligin family protein binding;GO:0046872//metal ion binding,K07377//Cell adhesion molecules (CAMs)
9380,60,2,1,4,13,8,4,0,35,0,6,1,GRHPR;glyoxylate reductase/hydroxypyruvate reductase,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005782//peroxisomal matrix;GO:0005737//cytoplasm,GO:0044281//small molecule metabolic process;GO:0051259//protein oligomerization;GO:0008152//metabolic process;GO:0046487//glyoxylate metabolic process;GO:0034641//cellular nitrogen compound metabolic process;GO:0043648//dicarboxylic acid metabolic process;GO:0055114//oxidation-reduction process;GO:0007588//excretion,GO:0016618//hydroxypyruvate reductase activity;GO:0070402//NADPH binding;GO:0051287//NAD binding;GO:0008465//glycerate dehydrogenase activity;GO:0042803//protein homodimerization activity;GO:0031406//carboxylic acid binding;GO:0030267//glyoxylate reductase (NADP) activity,"K00049//Glycine, serine and threonine metabolism;Pyruvate metabolism;Metabolic pathways;Glyoxylate and dicarboxylate metabolism"
9381,81,14,0,0,0,20,55,40,105,6,12,0,OTOF;otoferlin,GO:0030672//synaptic vesicle membrane;GO:0030054//cell junction;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane,GO:0016079//synaptic vesicle exocytosis;GO:0061025//membrane fusion;GO:0007605//sensory perception of sound,GO:0035612//AP-2 adaptor complex binding;GO:0005509//calcium ion binding,K02677//Amoebiasis;Phototransduction - fly;Wnt signaling pathway;Vascular smooth muscle contraction;Glutamatergic synapse;Amphetamine addiction;Natural killer cell mediated cytotoxicity;Long-term potentiation;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Pancreatic secretion;African trypanosomiasis;Phosphatidylinositol signaling system;MAPK signaling pathway - yeast;Melanogenesis;Vibrio cholerae infection;Non-small cell lung cancer;B cell receptor signaling pathway;Salivary secretion;Cholinergic synapse;Fc epsilon RI signaling pathway;Tight junction;GABAergic synapse;ErbB signaling pathway;Morphine addiction;MAPK signaling pathway;Influenza A;Serotonergic synapse;NF-kappa B signaling pathway;Chemokine signaling pathway;GnRH signaling pathway;Pathways in cancer;Dopaminergic synapse;Gap junction;Focal adhesion;VEGF signaling pathway;Glioma;Gastric acid secretion;Pathogenic Escherichia coli infection;Leishmaniasis;Leukocyte transendothelial migration;Retrograde endocannabinoid signaling;Calcium signaling pathway;Fc gamma R-mediated phagocytosis;Endocrine and other factor-regulated calcium reabsorption;Long-term depression
9382,69,94,100,159,358,0,36,59,53,0,210,328,COG1;component of oligomeric golgi complex 1,GO:0017119//Golgi transport complex;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,GO:0007030//Golgi organization;GO:0015031//protein transport;GO:0006891//intra-Golgi vesicle-mediated transport,GO:0005515//protein binding,-
9388,0,0,0,0,0,0,15,0,40,0,0,1,"LIPG;lipase, endothelial",GO:0005615//extracellular space,GO:0007584//response to nutrient;GO:0008283//cell proliferation;GO:0042632//cholesterol homeostasis;GO:0043691//reverse cholesterol transport;GO:0009395//phospholipid catabolic process;GO:0006629//lipid metabolic process;GO:0034375//high-density lipoprotein particle remodeling;GO:0050746//regulation of lipoprotein metabolic process;GO:0055091//phospholipid homeostasis;GO:0032376//positive regulation of cholesterol transport;GO:0010983//positive regulation of high-density lipoprotein particle clearance,GO:0008970//phosphatidylcholine 1-acylhydrolase activity;GO:0008201//heparin binding;GO:0004465//lipoprotein lipase activity;GO:0004620//phospholipase activity,K01046//Glycerophospholipid metabolism;alpha-Linolenic acid metabolism;Glycerolipid metabolism;Metabolic pathways
9389,0,0,0,0,0,0,0,0,17,0,0,0,"SLC22A14;solute carrier family 22, member 14",GO:0005887//integral component of plasma membrane,GO:0055085//transmembrane transport;GO:0015695//organic cation transport,GO:0015101//organic cation transmembrane transporter activity,-
939,0,134,98,180,206,0,62,0,47,0,180,0,CD27;CD27 molecule,GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005576//extracellular region;GO:0005887//integral component of plasma membrane,GO:0097191//extrinsic apoptotic signaling pathway;GO:0046330//positive regulation of JNK cascade;GO:0045471//response to ethanol;GO:0043066//negative regulation of apoptotic process;GO:0007166//cell surface receptor signaling pathway;GO:0070233//negative regulation of T cell apoptotic process;GO:0016064//immunoglobulin mediated immune response;GO:0045579//positive regulation of B cell differentiation;GO:0008588//release of cytoplasmic sequestered NF-kappaB;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0043027//cysteine-type endopeptidase inhibitor activity involved in apoptotic process,K05144//Cytokine-cytokine receptor interaction
9390,0,0,0,0,0,0,0,3,0,29,0,0,"SLC22A13;solute carrier family 22 (organic anion/urate transporter), member 13",GO:0005887//integral component of plasma membrane;GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0015695//organic cation transport;GO:0015747//urate transport;GO:2001142//nicotinate transport;GO:0055085//transmembrane transport,GO:0090416//nicotinate transporter activity;GO:0015101//organic cation transmembrane transporter activity,-
9391,0,57,0,36,96,11,0,0,24,127,19,0,CIAO1;cytosolic iron-sulfur assembly component 1,GO:0097361//CIA complex;GO:0071817//MMXD complex,GO:0007059//chromosome segregation;GO:0044281//small molecule metabolic process;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0016226//iron-sulfur cluster assembly;GO:0008284//positive regulation of cell proliferation,-,K04508//Wnt signaling pathway;K11447//Transcriptional misregulation in cancer
9392,0,35,0,0,51,1,0,0,42,0,0,0,"TGFBRAP1;transforming growth factor, beta receptor associated protein 1",GO:0016020//membrane;GO:0005737//cytoplasm,"GO:0050790//regulation of catalytic activity;GO:0007165//signal transduction;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0006886//intracellular protein transport;GO:0006355//regulation of transcription, DNA-templated;GO:0016192//vesicle-mediated transport",GO:0046332//SMAD binding;GO:0005083//small GTPase regulator activity;GO:0005160//transforming growth factor beta receptor binding;GO:0005515//protein binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K00797//Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;beta-Alanine metabolism;Metabolic pathways
9394,390,0,0,0,5,7,0,0,33,0,0,2,HS6ST1;heparan sulfate 6-O-sulfotransferase 1,GO:0005887//integral component of plasma membrane;GO:0000139//Golgi membrane,"GO:0060716//labyrinthine layer blood vessel development;GO:0006024//glycosaminoglycan biosynthetic process;GO:0001525//angiogenesis;GO:0048286//lung alveolus development;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0048666//neuron development;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:0005975//carbohydrate metabolic process",GO:0008146//sulfotransferase activity,K02514//Glycosaminoglycan biosynthesis - heparan sulfate
93953,13,0,0,0,0,7,21,0,18,0,0,0,ACRC;acidic repeat containing,GO:0005634//nucleus,-,-,-
9397,17,0,0,7,0,27,0,25,11,0,13,0,NMT2;N-myristoyltransferase 2,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm,"GO:0006499//N-terminal protein myristoylation;GO:0016032//viral process;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0016056//rhodopsin mediated signaling pathway;GO:0019082//viral protein processing;GO:0007603//phototransduction, visible light;GO:0075733//intracellular transport of virus;GO:0019068//virion assembly;GO:0009249//protein lipoylation",GO:0003824//catalytic activity;GO:0004379//glycylpeptide N-tetradecanoyltransferase activity,-
93973,0,0,2,0,21,0,0,0,41,191,0,0,ACTR8;ARP8 actin-related protein 8 homolog (yeast),GO:0031011//Ino80 complex;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006338//chromatin remodeling;GO:0006281//DNA repair;GO:0007067//mitotic nuclear division;GO:0006355//regulation of transcription, DNA-templated;GO:0006310//DNA recombination",GO:0005524//ATP binding;GO:0005515//protein binding,-
93974,0,0,0,19,20,0,0,0,0,0,0,0,ATPIF1;ATPase inhibitory factor 1,GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0009986//cell surface;GO:0005739//mitochondrion,GO:0001525//angiogenesis;GO:0051346//negative regulation of hydrolase activity;GO:0072593//reactive oxygen species metabolic process;GO:1901030//positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway;GO:0001937//negative regulation of endothelial cell proliferation;GO:0051289//protein homotetramerization;GO:0030218//erythrocyte differentiation;GO:0051260//protein homooligomerization;GO:0045980//negative regulation of nucleotide metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0006783//heme biosynthetic process,GO:0004857//enzyme inhibitor activity;GO:0005516//calmodulin binding;GO:0043532//angiostatin binding;GO:0051117//ATPase binding;GO:0042030//ATPase inhibitor activity;GO:0042803//protein homodimerization activity,-
93978,0,0,0,0,0,0,1,0,18,0,0,0,"CLEC6A;C-type lectin domain family 6, member A",GO:0016021//integral component of membrane,GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0050832//defense response to fungus;GO:0050715//positive regulation of cytokine secretion;GO:0045087//innate immune response,GO:0030246//carbohydrate binding,-
93979,0,0,0,0,0,22,0,69,9,0,0,0,CPA5;carboxypeptidase A5,GO:0005576//extracellular region,GO:0006508//proteolysis,GO:0008270//zinc ion binding;GO:0004181//metallocarboxypeptidase activity,-
9398,0,0,0,0,0,54,0,0,0,0,0,0,CD101;CD101 molecule,GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0008152//metabolic process;GO:0007166//cell surface receptor signaling pathway,"GO:0016812//hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides",-
93986,0,0,0,0,1,0,44,0,45,0,0,229,FOXP2;forkhead box P2,GO:0005634//nucleus,"GO:0021987//cerebral cortex development;GO:0045892//negative regulation of transcription, DNA-templated;GO:0007519//skeletal muscle tissue development;GO:0002053//positive regulation of mesenchymal cell proliferation;GO:0021758//putamen development;GO:0040007//growth;GO:0021757//caudate nucleus development;GO:0060501//positive regulation of epithelial cell proliferation involved in lung morphogenesis;GO:0009791//post-embryonic development;GO:0048745//smooth muscle tissue development;GO:0006351//transcription, DNA-templated;GO:0060013//righting reflex;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0021549//cerebellum development;GO:0048286//lung alveolus development;GO:0043010//camera-type eye development;GO:0042297//vocal learning",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0046872//metal ion binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003677//DNA binding;GO:0043565//sequence-specific DNA binding,-
9399,0,0,0,0,0,9,27,62,47,0,9,476,STOML1;stomatin (EPB72)-like 1,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K08764//PPAR signaling pathway;Primary bile acid biosynthesis;Metabolic pathways;Peroxisome;K03364//Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis;Cell cycle;K12405//Primary bile acid biosynthesis;Metabolic pathways;Peroxisome
94,10,0,44,0,0,14,0,61,26,0,0,0,ACVRL1;activin A receptor type II-like 1,GO:0043025//neuronal cell body;GO:0005887//integral component of plasma membrane;GO:0030425//dendrite;GO:0009986//cell surface,"GO:0051895//negative regulation of focal adhesion assembly;GO:0032924//activin receptor signaling pathway;GO:0071773//cellular response to BMP stimulus;GO:0001974//blood vessel remodeling;GO:0032332//positive regulation of chondrocyte differentiation;GO:0006355//regulation of transcription, DNA-templated;GO:2000279//negative regulation of DNA biosynthetic process;GO:0045766//positive regulation of angiogenesis;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0001938//positive regulation of endothelial cell proliferation;GO:0060841//venous blood vessel development;GO:0007165//signal transduction;GO:0035313//wound healing, spreading of epidermal cells;GO:0001937//negative regulation of endothelial cell proliferation;GO:0008015//blood circulation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006468//protein phosphorylation;GO:0051291//protein heterooligomerization;GO:0002043//blood vessel endothelial cell proliferation involved in sprouting angiogenesis;GO:0008217//regulation of blood pressure;GO:0007162//negative regulation of cell adhesion;GO:0043537//negative regulation of blood vessel endothelial cell migration;GO:0045603//positive regulation of endothelial cell differentiation;GO:0061154//endothelial tube morphogenesis;GO:0010862//positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0001525//angiogenesis;GO:0001936//regulation of endothelial cell proliferation;GO:0008285//negative regulation of cell proliferation;GO:0030509//BMP signaling pathway;GO:0030336//negative regulation of cell migration;GO:0071560//cellular response to transforming growth factor beta stimulus;GO:0030308//negative regulation of cell growth;GO:0023014//signal transduction by phosphorylation;GO:0006275//regulation of DNA replication;GO:0001946//lymphangiogenesis;GO:0030513//positive regulation of BMP signaling pathway;GO:0043535//regulation of blood vessel endothelial cell migration;GO:0001955//blood vessel maturation;GO:0060840//artery development;GO:0010596//negative regulation of endothelial cell migration;GO:0060836//lymphatic endothelial cell differentiation;GO:0045602//negative regulation of endothelial cell differentiation;GO:0061298//retina vasculature development in camera-type eye","GO:0005024//transforming growth factor beta-activated receptor activity;GO:0005025//transforming growth factor beta receptor activity, type I;GO:0048185//activin binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0004674//protein serine/threonine kinase activity;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0046332//SMAD binding;GO:0016361//activin receptor activity, type I;GO:0005524//ATP binding;GO:0050431//transforming growth factor beta binding;GO:0019901//protein kinase binding",-
940,84,0,0,11,0,0,0,34,17,160,0,0,CD28;CD28 molecule,GO:0001772//immunological synapse;GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0045070//positive regulation of viral genome replication;GO:0045060//negative thymic T cell selection;GO:0031295//T cell costimulation;GO:0045087//innate immune response;GO:0002863//positive regulation of inflammatory response to antigenic stimulus;GO:0048304//positive regulation of isotype switching to IgG isotypes;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045066//regulatory T cell differentiation;GO:0042089//cytokine biosynthetic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0045727//positive regulation of translation;GO:0042102//positive regulation of T cell proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0016032//viral process;GO:0050852//T cell receptor signaling pathway;GO:0050690//regulation of defense response to virus by virus;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0006959//humoral immune response;GO:0007166//cell surface receptor signaling pathway;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0045840//positive regulation of mitosis,GO:0002020//protease binding;GO:0015026//coreceptor activity;GO:0005070//SH3/SH2 adaptor activity;GO:0042802//identical protein binding;GO:0005515//protein binding,K06470//Measles;Allograft rejection;Viral myocarditis;Systemic lupus erythematosus;Graft-versus-host disease;T cell receptor signaling pathway;Cell adhesion molecules (CAMs);Type I diabetes mellitus;Intestinal immune network for IgA production;Autoimmune thyroid disease;Rheumatoid arthritis
9400,107,0,0,1,13,0,0,1,51,0,42,518,RECQL5;RecQ protein-like 5,"GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0016591//DNA-directed RNA polymerase II, holoenzyme;GO:0005737//cytoplasm",GO:0051304//chromosome separation;GO:0034244//negative regulation of transcription elongation from RNA polymerase II promoter;GO:0032508//DNA duplex unwinding;GO:0006260//DNA replication;GO:0006310//DNA recombination;GO:0006259//DNA metabolic process;GO:0006200//ATP catabolic process;GO:0007067//mitotic nuclear division;GO:0006281//DNA repair,GO:0008026//ATP-dependent helicase activity;GO:0003678//DNA helicase activity;GO:0003676//nucleic acid binding;GO:0005524//ATP binding;GO:0000993//RNA polymerase II core binding,-
94005,0,0,1,2,25,0,23,0,9,0,0,131,"PIGS;phosphatidylinositol glycan anchor biosynthesis, class S",GO:0016020//membrane;GO:0042765//GPI-anchor transamidase complex;GO:0005789//endoplasmic reticulum membrane,GO:0043687//post-translational protein modification;GO:0016255//attachment of GPI anchor to protein;GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process,GO:0005515//protein binding;GO:0003923//GPI-anchor transamidase activity,K05291//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
94009,0,250,97,277,395,0,63,367,121,1,516,0,SERHL;serine hydrolase-like,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity,-
9401,0,0,0,0,0,0,0,0,10,0,1,0,RECQL4;RecQ protein-like 4,GO:0016020//membrane;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006310//DNA recombination;GO:0006200//ATP catabolic process;GO:0032508//DNA duplex unwinding;GO:0007275//multicellular organismal development;GO:0006281//DNA repair;GO:0006260//DNA replication;GO:0000733//DNA strand renaturation,GO:0008270//zinc ion binding;GO:0036310//annealing helicase activity;GO:0043140//ATP-dependent 3'-5' DNA helicase activity;GO:0000405//bubble DNA binding;GO:0005524//ATP binding,-
94015,0,0,0,0,0,20,34,18,54,187,6,0,TTYH2;tweety family member 2,GO:0034707//chloride channel complex;GO:0005886//plasma membrane,GO:1902476//chloride transmembrane transport,GO:0005254//chloride channel activity;GO:0005515//protein binding,-
9402,82,0,0,0,0,3,0,65,54,0,0,0,GRAP2;GRB2-related adaptor protein 2,GO:0005730//nucleolus;GO:0005768//endosome;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0045087//innate immune response;GO:0031295//T cell costimulation;GO:0007267//cell-cell signaling;GO:0009967//positive regulation of signal transduction;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007265//Ras protein signal transduction;GO:0050852//T cell receptor signaling pathway,GO:0005070//SH3/SH2 adaptor activity;GO:0005515//protein binding,K07366//T cell receptor signaling pathway
94025,73,0,70,0,12,75,153,72,355,272,119,0,"MUC16;mucin 16, cell surface associated",GO:0031982//vesicle;GO:0019898//extrinsic component of membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome;GO:0005796//Golgi lumen;GO:0005886//plasma membrane,GO:0016266//O-glycan processing;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0007155//cell adhesion,GO:0005515//protein binding,K10955//Vibrio cholerae infection;Amoebiasis
94026,112,0,0,0,0,0,18,0,30,0,4,0,POM121L2;POM121 transmembrane nucleoporin-like 2,-,-,-,K14316//RNA transport
94027,0,0,0,0,0,0,0,0,0,0,8,0,"CGB7;chorionic gonadotropin, beta polypeptide 7",-,-,-,-
9403,101,0,0,5,32,0,0,0,15,0,0,0,SEP15;15 kDa selenoprotein,GO:0070062//extracellular vesicular exosome;GO:0005788//endoplasmic reticulum lumen,GO:0051084//'de novo' posttranslational protein folding,GO:0008430//selenium binding,-
94030,0,0,0,0,0,0,12,0,46,0,0,0,LRRC4B;leucine rich repeat containing 4B,GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0044300//cerebellar mossy fiber,GO:0051965//positive regulation of synapse assembly,GO:0005102//receptor binding,K07523//Axon guidance
94031,0,0,0,0,0,0,23,0,0,0,0,0,HTRA3;HtrA serine peptidase 3,GO:0005576//extracellular region,GO:0030514//negative regulation of BMP signaling pathway;GO:0006508//proteolysis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0001558//regulation of cell growth,GO:0005515//protein binding;GO:0004252//serine-type endopeptidase activity;GO:0005520//insulin-like growth factor binding;GO:0004175//endopeptidase activity;GO:0008236//serine-type peptidase activity,-
94032,0,0,0,0,0,0,0,0,13,0,0,0,CAMK2N2;calcium/calmodulin-dependent protein kinase II inhibitor 2,GO:0005634//nucleus;GO:0005829//cytosol,GO:0006469//negative regulation of protein kinase activity,GO:0019901//protein kinase binding;GO:0008427//calcium-dependent protein kinase inhibitor activity,-
9404,0,3,0,6,6,0,0,0,18,0,0,0,LPXN;leupaxin,GO:0005737//cytoplasm;GO:0016020//membrane;GO:0005886//plasma membrane;GO:0002102//podosome;GO:0042995//cell projection;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005925//focal adhesion,"GO:0007155//cell adhesion;GO:0033628//regulation of cell adhesion mediated by integrin;GO:0007162//negative regulation of cell adhesion;GO:0006351//transcription, DNA-templated;GO:0050859//negative regulation of B cell receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0007165//signal transduction;GO:0006461//protein complex assembly",GO:0003712//transcription cofactor activity;GO:0008270//zinc ion binding;GO:0005515//protein binding,K05760//Leukocyte transendothelial migration;VEGF signaling pathway;Focal adhesion;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway
94056,0,78,2,60,83,0,0,0,8,43,0,0,SYAP1;synapse associated protein 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005730//nucleolus,-,-,K01539//Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
9406,0,0,1,43,110,0,0,51,0,0,0,0,"ZRANB2;zinc finger, RAN-binding domain containing 2",GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0006355//regulation of transcription, DNA-templated",GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003723//RNA binding,K13098//Transcriptional misregulation in cancer;K14651//Transcriptional misregulation in cancer;Basal transcription factors
9407,0,0,0,0,0,24,3,0,0,0,0,0,"TMPRSS11D;transmembrane protease, serine 11D",GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005887//integral component of plasma membrane,GO:0007585//respiratory gaseous exchange;GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0004252//serine-type endopeptidase activity,-
94081,0,0,0,37,62,37,0,0,19,0,14,0,SFXN1;sideroflexin 1,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0030218//erythrocyte differentiation;GO:0055072//iron ion homeostasis;GO:0006826//iron ion transport,GO:0008324//cation transmembrane transporter activity,K03351//Progesterone-mediated oocyte maturation;Ubiquitin mediated proteolysis;Cell cycle - yeast;Cell cycle;HTLV-I infection;Oocyte meiosis;Meiosis - yeast
9409,116,1,0,0,0,0,14,0,12,0,9,0,PEX16;peroxisomal biogenesis factor 16,GO:0005777//peroxisome;GO:0005789//endoplasmic reticulum membrane;GO:0005779//integral component of peroxisomal membrane;GO:0005778//peroxisomal membrane;GO:0016020//membrane;GO:0005783//endoplasmic reticulum,GO:0070972//protein localization to endoplasmic reticulum;GO:0016557//peroxisome membrane biogenesis;GO:0007031//peroxisome organization;GO:0016558//protein import into peroxisome matrix;GO:0032581//ER-dependent peroxisome organization;GO:0006625//protein targeting to peroxisome;GO:0045046//protein import into peroxisome membrane;GO:0022615//protein to membrane docking,GO:0008022//protein C-terminus binding;GO:0005515//protein binding,K13335//Peroxisome
94097,0,0,0,5,2,0,32,0,6,0,0,0,SFXN5;sideroflexin 5,GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane,GO:0055072//iron ion homeostasis;GO:0015746//citrate transport,GO:0008324//cation transmembrane transporter activity;GO:0015137//citrate transmembrane transporter activity,K03351//Cell cycle;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Ubiquitin mediated proteolysis;HTLV-I infection;Oocyte meiosis;Meiosis - yeast
941,0,0,0,0,0,17,0,0,19,0,0,0,CD80;CD80 molecule,GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane,"GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0046641//positive regulation of alpha-beta T cell proliferation;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0045425//positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016032//viral process;GO:0042110//T cell activation;GO:0035556//intracellular signal transduction;GO:0048015//phosphatidylinositol-mediated signaling;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0009967//positive regulation of signal transduction;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0031295//T cell costimulation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045087//innate immune response",GO:0005515//protein binding;GO:0015026//coreceptor activity,K05412//Rheumatoid arthritis;Autoimmune thyroid disease;Toll-like receptor signaling pathway;Intestinal immune network for IgA production;Type I diabetes mellitus;Allograft rejection;Cell adhesion molecules (CAMs);Graft-versus-host disease;Viral myocarditis;Systemic lupus erythematosus
9410,0,0,1,0,8,1,28,0,10,0,1,0,SNRNP40;small nuclear ribonucleoprotein 40kDa (U5),GO:0005682//U5 snRNP;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0005634//nucleus;GO:0005732//small nucleolar ribonucleoprotein complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0000398//mRNA splicing, via spliceosome;GO:0000375//RNA splicing, via transesterification reactions;GO:0006396//RNA processing;GO:0010467//gene expression;GO:0008380//RNA splicing",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,K12857//Spliceosome
94101,0,0,12,0,24,0,0,0,45,0,0,0,ORMDL1;ORMDL sphingolipid biosynthesis regulator 1,GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane,GO:0006672//ceramide metabolic process,-,K12667//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis;Protein processing in endoplasmic reticulum
94103,0,0,0,0,2,14,0,47,11,0,0,0,ORMDL3;ORMDL sphingolipid biosynthesis regulator 3,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0035339//SPOTS complex;GO:0005789//endoplasmic reticulum membrane,GO:0006672//ceramide metabolic process,GO:0005515//protein binding,K12667//Various types of N-glycan biosynthesis;Metabolic pathways;N-Glycan biosynthesis;Protein processing in endoplasmic reticulum
94104,0,0,0,9,13,53,15,0,18,0,0,0,PAXBP1;PAX3 and PAX7 binding protein 1,GO:0005829//cytosol;GO:0005634//nucleus,"GO:0007517//muscle organ development;GO:0031062//positive regulation of histone methylation;GO:0014842//regulation of satellite cell proliferation;GO:2000288//positive regulation of myoblast proliferation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0008134//transcription factor binding;GO:0003677//DNA binding,-
94107,0,0,0,10,0,0,13,0,0,0,0,0,TMEM203;transmembrane protein 203,GO:0016021//integral component of membrane,-,-,-
9411,0,130,2,20,139,30,85,0,37,0,0,0,ARHGAP29;Rho GTPase activating protein 29,GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0007266//Rho protein signal transduction,GO:0030165//PDZ domain binding;GO:0046872//metal ion binding;GO:0005100//Rho GTPase activator activity,K04450//Influenza A;Alcoholism;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction;K02649//Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;T cell receptor signaling pathway;Type II diabetes mellitus;Amoebiasis;Colorectal cancer;Insulin signaling pathway;Phosphatidylinositol signaling system;Carbohydrate digestion and absorption;Small cell lung cancer;Progesterone-mediated oocyte maturation;Aldosterone-regulated sodium reabsorption;Prostate cancer;Regulation of actin cytoskeleton;Melanoma;Neurotrophin signaling pathway;Hepatitis C;Non-small cell lung cancer;Measles;Fc epsilon RI signaling pathway;Cholinergic synapse;Acute myeloid leukemia;Chagas disease (American trypanosomiasis);B cell receptor signaling pathway;mTOR signaling pathway;Apoptosis;Renal cell carcinoma;Epstein-Barr virus infection;ErbB signaling pathway;Pancreatic cancer;Chemokine signaling pathway;Pathways in cancer;Toll-like receptor signaling pathway;Influenza A;Endometrial cancer;Osteoclast differentiation;Toxoplasmosis;VEGF signaling pathway;Focal adhesion;Glioma;HTLV-I infection;Bacterial invasion of epithelial cells;Jak-STAT signaling pathway;Leukocyte transendothelial migration;Fc gamma R-mediated phagocytosis
9412,0,0,1,33,29,0,0,0,0,0,0,0,MED21;mediator complex subunit 21,GO:0016592//mediator complex,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0001824//blastocyst development;GO:0019827//stem cell maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0003713//transcription coactivator activity;GO:0003899//DNA-directed RNA polymerase activity,-
94120,0,40,28,64,54,0,5,0,43,5,144,8,SYTL3;synaptotagmin-like 3,GO:0012505//endomembrane system;GO:0016020//membrane,GO:0006887//exocytosis;GO:0006886//intracellular protein transport,GO:0017137//Rab GTPase binding;GO:0005544//calcium-dependent phospholipid binding,K15290//Synaptic vesicle cycle
94121,0,257,4,137,463,0,25,0,1,0,0,1,SYTL4;synaptotagmin-like 4,GO:0005730//nucleolus;GO:0030141//secretory granule;GO:0005634//nucleus;GO:0005768//endosome;GO:0005886//plasma membrane;GO:0008021//synaptic vesicle;GO:0019898//extrinsic component of membrane;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0030658//transport vesicle membrane,GO:0071985//multivesicular body sorting pathway;GO:0045921//positive regulation of exocytosis;GO:0046676//negative regulation of insulin secretion;GO:0006886//intracellular protein transport;GO:0050714//positive regulation of protein secretion;GO:0006887//exocytosis,GO:0005543//phospholipid binding;GO:0008270//zinc ion binding;GO:0017137//Rab GTPase binding;GO:0042043//neurexin family protein binding;GO:0005215//transporter activity,K15290//Synaptic vesicle cycle
94122,0,38,2,17,148,34,1,0,58,0,1,0,SYTL5;synaptotagmin-like 5,GO:0016020//membrane,GO:0006886//intracellular protein transport;GO:0006887//exocytosis,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0017137//Rab GTPase binding,K15290//Synaptic vesicle cycle
9413,0,17,0,11,0,0,0,0,19,0,0,0,"FAM189A2;family with sequence similarity 189, member A2",GO:0016021//integral component of membrane,-,-,-
94134,217,47,0,27,164,20,35,64,88,4,0,0,ARHGAP12;Rho GTPase activating protein 12,GO:0005829//cytosol,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0002011//morphogenesis of an epithelial sheet;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K04450//MAPK signaling pathway;Amphetamine addiction;Epstein-Barr virus infection;HTLV-I infection;Cocaine addiction;Dopaminergic synapse;Influenza A;Alcoholism;K08878//Chronic myeloid leukemia;Pathways in cancer
94137,0,1,0,0,0,9,26,14,48,0,6,0,RP1L1;retinitis pigmentosa 1-like 1,GO:0005874//microtubule;GO:0032391//photoreceptor connecting cilium;GO:0001750//photoreceptor outer segment;GO:0005930//axoneme;GO:0070062//extracellular vesicular exosome,GO:0045494//photoreceptor cell maintenance;GO:0042461//photoreceptor cell development;GO:0035556//intracellular signal transduction;GO:0007601//visual perception;GO:0030030//cell projection organization,-,-
9414,129,0,0,0,66,68,62,49,80,6,0,215,TJP2;tight junction protein 2,GO:0005912//adherens junction;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005886//plasma membrane;GO:0005923//tight junction;GO:0030054//cell junction;GO:0005829//cytosol,GO:0006915//apoptotic process;GO:0010033//response to organic substance;GO:0035329//hippo signaling;GO:0046939//nucleotide phosphorylation;GO:0006921//cellular component disassembly involved in execution phase of apoptosis,GO:0008022//protein C-terminus binding;GO:0004385//guanylate kinase activity;GO:0005515//protein binding,K06098//Tight junction;Vibrio cholerae infection
9415,0,14,0,18,95,0,19,0,39,0,68,0,FADS2;fatty acid desaturase 2,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane,GO:0044281//small molecule metabolic process;GO:0036109//alpha-linolenic acid metabolic process;GO:0006636//unsaturated fatty acid biosynthetic process;GO:0043651//linoleic acid metabolic process;GO:0055114//oxidation-reduction process,GO:0005506//iron ion binding;GO:0004768//stearoyl-CoA 9-desaturase activity;GO:0020037//heme binding,K10226//PPAR signaling pathway;Biosynthesis of unsaturated fatty acids;alpha-Linolenic acid metabolism
9416,0,17,1,0,29,0,0,1,22,0,0,0,DDX23;DEAD (Asp-Glu-Ala-Asp) box polypeptide 23,GO:0005730//nucleolus;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005682//U5 snRNP;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0071013//catalytic step 2 spliceosome;GO:0005654//nucleoplasm,"GO:0010467//gene expression;GO:0006200//ATP catabolic process;GO:0008380//RNA splicing;GO:0000375//RNA splicing, via transesterification reactions;GO:0000398//mRNA splicing, via spliceosome;GO:0000354//cis assembly of pre-catalytic spliceosome",GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0008026//ATP-dependent helicase activity;GO:0005524//ATP binding,K12858//Spliceosome
94160,0,0,0,0,0,7,24,0,23,129,5,0,"ABCC12;ATP-binding cassette, sub-family C (CFTR/MRP), member 12",GO:0016021//integral component of membrane,GO:0006200//ATP catabolic process;GO:0055085//transmembrane transport,"GO:0005524//ATP binding;GO:0042626//ATPase activity, coupled to transmembrane movement of substances",K05672//ABC transporters
9419,0,31,1,15,122,1,0,17,18,0,10,0,CRIPT;cysteine-rich PDZ-binding protein,GO:0030425//dendrite;GO:0043198//dendritic shaft;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0043197//dendritic spine,GO:0045184//establishment of protein localization;GO:0031122//cytoplasmic microtubule organization;GO:0035372//protein localization to microtubule;GO:1902897//regulation of postsynaptic density protein 95 clustering,GO:0030165//PDZ domain binding;GO:0032403//protein complex binding;GO:0005515//protein binding;GO:0008017//microtubule binding,K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K11447//Transcriptional misregulation in cancer
942,0,0,0,0,0,28,0,0,26,134,1,0,CD86;CD86 molecule,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0016021//integral component of membrane;GO:0009986//cell surface;GO:0043231//intracellular membrane-bounded organelle,"GO:0001878//response to yeast;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0034341//response to interferon-gamma;GO:0045404//positive regulation of interleukin-4 biosynthetic process;GO:0071248//cellular response to metal ion;GO:0045086//positive regulation of interleukin-2 biosynthetic process;GO:0043017//positive regulation of lymphotoxin A biosynthetic process;GO:0042113//B cell activation;GO:0071222//cellular response to lipopolysaccharide;GO:0002668//negative regulation of T cell anergy;GO:0042104//positive regulation of activated T cell proliferation;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0007568//aging;GO:0071345//cellular response to cytokine stimulus;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0045630//positive regulation of T-helper 2 cell differentiation;GO:0042110//T cell activation;GO:0002224//toll-like receptor signaling pathway;GO:0006955//immune response;GO:0002309//T cell proliferation involved in immune response;GO:0043011//myeloid dendritic cell differentiation;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0045087//innate immune response;GO:0008284//positive regulation of cell proliferation;GO:0042493//response to drug;GO:0031295//T cell costimulation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007267//cell-cell signaling;GO:0048011//neurotrophin TRK receptor signaling pathway",GO:0015026//coreceptor activity;GO:0004872//receptor activity;GO:0005102//receptor binding;GO:0005515//protein binding,K05413//Toll-like receptor signaling pathway;Intestinal immune network for IgA production;Type I diabetes mellitus;Transcriptional misregulation in cancer;Rheumatoid arthritis;Autoimmune thyroid disease;Allograft rejection;Cell adhesion molecules (CAMs);Systemic lupus erythematosus;Viral myocarditis;Graft-versus-host disease
9420,111,0,0,0,0,14,0,0,27,0,1,0,"CYP7B1;cytochrome P450, family 7, subfamily B, polypeptide 1",GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0008219//cell death;GO:0016125//sterol metabolic process;GO:0033147//negative regulation of intracellular estrogen receptor signaling pathway;GO:0008206//bile acid metabolic process;GO:0050679//positive regulation of epithelial cell proliferation;GO:0006699//bile acid biosynthetic process;GO:0008203//cholesterol metabolic process;GO:0055114//oxidation-reduction process;GO:0060740//prostate gland epithelium morphogenesis,GO:0008396//oxysterol 7-alpha-hydroxylase activity;GO:0020037//heme binding;GO:0033783//25-hydroxycholesterol 7alpha-hydroxylase activity;GO:0005506//iron ion binding,K07430//Steroid hormone biosynthesis;Primary bile acid biosynthesis
9421,25,0,0,0,0,18,0,0,7,0,0,0,HAND1;heart and neural crest derivatives expressed 1,GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0001947//heart looping;GO:0001824//blastocyst development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0055010//ventricular cardiac muscle tissue morphogenesis;GO:0060707//trophoblast giant cell differentiation;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0001707//mesoderm formation;GO:0060411//cardiac septum morphogenesis;GO:0007507//heart development;GO:0001525//angiogenesis;GO:0003219//cardiac right ventricle formation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0060485//mesenchyme development;GO:0006366//transcription from RNA polymerase II promoter;GO:0003218//cardiac left ventricle formation;GO:0042475//odontogenesis of dentin-containing tooth;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0035050//embryonic heart tube development;GO:0060536//cartilage morphogenesis;GO:0001829//trophectodermal cell differentiation",GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0008134//transcription factor binding;GO:0044212//transcription regulatory region DNA binding;GO:0043565//sequence-specific DNA binding;GO:0042802//identical protein binding;GO:0019899//enzyme binding;GO:0043425//bHLH transcription factor binding;GO:0003713//transcription coactivator activity,-
9422,247,1,0,32,26,27,0,0,66,0,0,0,ZNF264;zinc finger protein 264,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9423,0,0,0,0,0,0,16,55,4,0,20,0,NTN1;netrin 1,GO:0005737//cytoplasm;GO:0005576//extracellular region;GO:0005604//basement membrane,GO:0006915//apoptotic process;GO:0033564//anterior/posterior axon guidance;GO:0001764//neuron migration;GO:0045773//positive regulation of axon extension;GO:0007411//axon guidance;GO:0016337//single organismal cell-cell adhesion;GO:0060603//mammary gland duct morphogenesis;GO:0042472//inner ear morphogenesis;GO:0030517//negative regulation of axon extension;GO:0040023//establishment of nucleus localization;GO:0008284//positive regulation of cell proliferation;GO:0030334//regulation of cell migration,GO:0005515//protein binding,K06843//Axon guidance
94233,0,0,0,0,0,0,42,0,14,147,1,1,OPN4;opsin 4,GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0018298//protein-chromophore linkage;GO:0048511//rhythmic process;GO:0016056//rhodopsin mediated signaling pathway;GO:0042752//regulation of circadian rhythm;GO:0007602//phototransduction;GO:0007601//visual perception,GO:0008020//G-protein coupled photoreceptor activity;GO:0005502//11-cis retinal binding,-
94234,0,0,0,0,0,0,28,0,33,0,4,0,FOXQ1;forkhead box Q1,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0031069//hair follicle morphogenesis;GO:0006355//regulation of transcription, DNA-templated",GO:0043565//sequence-specific DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
94235,0,0,0,0,0,0,21,0,4,0,0,0,"GNG8;guanine nucleotide binding protein (G protein), gamma 8",GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0044281//small molecule metabolic process;GO:0007268//synaptic transmission;GO:0007399//nervous system development;GO:0006112//energy reserve metabolic process;GO:0071377//cellular response to glucagon stimulus;GO:0006184//GTP catabolic process,GO:0003924//GTPase activity;GO:0005515//protein binding;GO:0004871//signal transducer activity,K04544//Alcoholism;Serotonergic synapse;Retrograde endocannabinoid signaling;Dopaminergic synapse;GABAergic synapse;Chemokine signaling pathway;Cholinergic synapse;Glutamatergic synapse;Morphine addiction
94239,0,68,1,74,216,25,44,0,25,0,1,0,"H2AFV;H2A histone family, member V",GO:0005634//nucleus;GO:0000786//nucleosome;GO:0070062//extracellular vesicular exosome,-,GO:0046982//protein heterodimerization activity;GO:0003677//DNA binding,K11251//Alcoholism;Systemic lupus erythematosus
9424,0,0,0,5,4,0,0,0,8,0,1,0,"KCNK6;potassium channel, subfamily K, member 6",GO:0008076//voltage-gated potassium channel complex;GO:0005886//plasma membrane,GO:0060075//regulation of resting membrane potential;GO:0006813//potassium ion transport;GO:0007268//synaptic transmission;GO:0034765//regulation of ion transmembrane transport;GO:0003085//negative regulation of systemic arterial blood pressure;GO:0071805//potassium ion transmembrane transport,GO:0005242//inward rectifier potassium channel activity,-
94240,0,0,0,0,18,0,0,0,57,0,0,0,EPSTI1;epithelial stromal interaction 1 (breast),-,-,-,K03243//RNA transport
94241,44,62,1,105,246,0,0,0,16,0,18,0,TP53INP1;tumor protein p53 inducible nuclear protein 1,GO:0005829//cytosol;GO:0016605//PML body;GO:0031410//cytoplasmic vesicle;GO:0005634//nucleus;GO:0005776//autophagic vacuole,"GO:0043065//positive regulation of apoptotic process;GO:0006950//response to stress;GO:2001235//positive regulation of apoptotic signaling pathway;GO:0048102//autophagic cell death;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0007050//cell cycle arrest;GO:0071361//cellular response to ethanol;GO:0030336//negative regulation of cell migration;GO:0008285//negative regulation of cell proliferation;GO:0072703//cellular response to methyl methanesulfonate;GO:0071447//cellular response to hydroperoxide;GO:0006351//transcription, DNA-templated;GO:0034644//cellular response to UV;GO:0009408//response to heat;GO:0010508//positive regulation of autophagy;GO:0045893//positive regulation of transcription, DNA-templated",GO:0016209//antioxidant activity;GO:0005515//protein binding,K15310//HTLV-I infection
9425,88,0,0,10,0,0,33,0,44,0,3,0,"CDYL;chromodomain protein, Y-like",GO:0005634//nucleus,"GO:0007283//spermatogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0016573//histone acetylation",GO:0005515//protein binding;GO:0004402//histone acetyltransferase activity;GO:0035064//methylated histone binding;GO:0003714//transcription corepressor activity,K13239//Fatty acid metabolism;Peroxisome
9427,0,0,0,0,0,0,54,70,54,0,0,0,ECEL1;endothelin converting enzyme-like 1,GO:0005887//integral component of plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0006508//proteolysis;GO:0003016//respiratory system process,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity,-
94274,0,0,0,0,0,0,9,65,0,0,0,0,"PPP1R14A;protein phosphatase 1, regulatory (inhibitor) subunit 14A",GO:0005737//cytoplasm,GO:0042325//regulation of phosphorylation;GO:0043086//negative regulation of catalytic activity,GO:0004864//protein phosphatase inhibitor activity,K12328//Vascular smooth muscle contraction
9429,0,0,0,0,0,26,0,0,74,0,0,14,"ABCG2;ATP-binding cassette, sub-family G (WHITE), member 2",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0031966//mitochondrial membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane,GO:0046618//drug export;GO:0015886//heme transport;GO:0042493//response to drug;GO:0051593//response to folic acid;GO:0051384//response to glucocorticoid;GO:0006879//cellular iron ion homeostasis;GO:0010039//response to iron ion;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0046415//urate metabolic process;GO:0006810//transport;GO:0006855//drug transmembrane transport;GO:0060136//embryonic process involved in female pregnancy;GO:0055085//transmembrane transport;GO:0042908//xenobiotic transport,"GO:0008559//xenobiotic-transporting ATPase activity;GO:0042626//ATPase activity, coupled to transmembrane movement of substances;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0015232//heme transporter activity;GO:0005524//ATP binding;GO:0005215//transporter activity",K05681//ABC transporters;Bile secretion
943,65,0,0,0,0,18,0,1,36,0,14,0,"TNFRSF8;tumor necrosis factor receptor superfamily, member 8",GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0042535//positive regulation of tumor necrosis factor biosynthetic process;GO:0071260//cellular response to mechanical stimulus;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0043065//positive regulation of apoptotic process;GO:0045556//positive regulation of TRAIL biosynthetic process,GO:0004888//transmembrane signaling receptor activity,K05145//Cytokine-cytokine receptor interaction
9435,66,25,0,0,0,0,40,47,27,192,0,0,CHST2;carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0031228//intrinsic component of Golgi membrane;GO:0005802//trans-Golgi network,GO:0006044//N-acetylglucosamine metabolic process;GO:0007275//multicellular organismal development;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0005975//carbohydrate metabolic process;GO:0006790//sulfur compound metabolic process;GO:0006954//inflammatory response;GO:0018146//keratan sulfate biosynthetic process,GO:0001517//N-acetylglucosamine 6-O-sulfotransferase activity;GO:0008146//sulfotransferase activity,K04745//Glycosaminoglycan biosynthesis - keratan sulfate
9436,0,0,0,0,0,0,0,111,1,0,0,0,NCR2;natural cytotoxicity triggering receptor 2,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0006968//cellular defense response;GO:0045087//innate immune response;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity,K06742//Natural killer cell mediated cytotoxicity
9437,146,0,0,0,0,0,0,0,0,0,0,0,NCR1;natural cytotoxicity triggering receptor 1,GO:0005887//integral component of plasma membrane;GO:0016514//SWI/SNF complex,GO:0042269//regulation of natural killer cell mediated cytotoxicity;GO:0007165//signal transduction;GO:0030101//natural killer cell activation;GO:0035556//intracellular signal transduction;GO:0006968//cellular defense response,GO:0005057//receptor signaling protein activity,K06741//Natural killer cell mediated cytotoxicity
9439,0,0,0,16,68,0,23,0,41,93,0,0,MED23;mediator complex subunit 23,GO:0016592//mediator complex;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,"GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006355//regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003713//transcription coactivator activity,-
944,0,0,0,0,0,13,36,0,0,0,0,0,"TNFSF8;tumor necrosis factor (ligand) superfamily, member 8",GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space,"GO:0006915//apoptotic process;GO:0008283//cell proliferation;GO:0006955//immune response;GO:0007165//signal transduction;GO:0043374//CD8-positive, alpha-beta T cell differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0050830//defense response to Gram-positive bacterium;GO:0007267//cell-cell signaling",GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity;GO:0005102//receptor binding,K05471//Cytokine-cytokine receptor interaction
9440,22,0,0,32,25,13,10,0,2,0,10,0,MED17;mediator complex subunit 17,GO:0016020//membrane;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005654//nucleoplasm,"GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0019827//stem cell maintenance",GO:0001104//RNA polymerase II transcription cofactor activity;GO:0042809//vitamin D receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0004872//receptor activity;GO:0003712//transcription cofactor activity;GO:0046966//thyroid hormone receptor binding;GO:0003713//transcription coactivator activity,-
9441,0,0,0,4,15,19,0,0,5,120,38,0,MED26;mediator complex subunit 26,GO:0005654//nucleoplasm;GO:0016592//mediator complex,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter,GO:0003713//transcription coactivator activity;GO:0003677//DNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,-
9442,0,0,0,7,0,0,13,0,15,0,0,0,MED27;mediator complex subunit 27,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0016592//mediator complex;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0005730//nucleolus,GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0019827//stem cell maintenance,GO:0003713//transcription coactivator activity,-
9443,0,0,0,0,7,0,0,0,8,0,0,0,MED7;mediator complex subunit 7,GO:0005739//mitochondrion;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0031965//nuclear membrane;GO:0005654//nucleoplasm,GO:0019827//stem cell maintenance;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter,GO:0003713//transcription coactivator activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding,-
9444,0,0,0,0,0,6,21,0,51,0,0,0,"QKI;QKI, KH domain containing, RNA binding",GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0051028//mRNA transport;GO:0007286//spermatid development;GO:0042692//muscle cell differentiation;GO:0001570//vasculogenesis;GO:0042759//long-chain fatty acid biosynthetic process;GO:0042552//myelination;GO:0008380//RNA splicing;GO:0010628//positive regulation of gene expression;GO:0006397//mRNA processing;GO:0006417//regulation of translation,GO:0017124//SH3 domain binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
9445,0,14,0,1,56,0,19,0,30,0,20,0,ITM2B;integral membrane protein 2B,GO:0031301//integral component of organelle membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005615//extracellular space;GO:0005794//Golgi apparatus;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0030660//Golgi-associated vesicle membrane,GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand;GO:0042985//negative regulation of amyloid precursor protein biosynthetic process;GO:0007399//nervous system development,GO:0001540//beta-amyloid binding;GO:0005524//ATP binding;GO:0005515//protein binding,-
9446,21,0,0,21,1,18,0,0,10,0,2,0,GSTO1;glutathione S-transferase omega 1,GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity;GO:0042178//xenobiotic catabolic process;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0019852//L-ascorbic acid metabolic process;GO:1901687//glutathione derivative biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006805//xenobiotic metabolic process;GO:0055114//oxidation-reduction process;GO:0060315//negative regulation of ryanodine-sensitive calcium-release channel activity;GO:0014810//positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion;GO:0010881//regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion;GO:0071243//cellular response to arsenic-containing substance,GO:0004364//glutathione transferase activity;GO:0045174//glutathione dehydrogenase (ascorbate) activity;GO:0016491//oxidoreductase activity;GO:0050610//methylarsonate reductase activity,K00799//Pathways in cancer;Drug metabolism - cytochrome P450;Prostate cancer;Glutathione metabolism;Metabolism of xenobiotics by cytochrome P450
9447,0,0,0,0,0,0,24,0,9,0,0,0,AIM2;absent in melanoma 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0097169//AIM2 inflammasome complex;GO:0005829//cytosol,"GO:0006915//apoptotic process;GO:0002230//positive regulation of defense response to virus by host;GO:0035872//nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway;GO:0006954//inflammatory response;GO:0032461//positive regulation of protein oligomerization;GO:0002218//activation of innate immune response;GO:0032088//negative regulation of NF-kappaB transcription factor activity;GO:0050702//interleukin-1 beta secretion;GO:0006955//immune response;GO:0035690//cellular response to drug;GO:0050718//positive regulation of interleukin-1 beta secretion;GO:0035458//cellular response to interferon-beta;GO:0045087//innate immune response;GO:2001056//positive regulation of cysteine-type endopeptidase activity;GO:0033209//tumor necrosis factor-mediated signaling pathway;GO:0070269//pyroptosis;GO:0032731//positive regulation of interleukin-1 beta production;GO:0051092//positive regulation of NF-kappaB transcription factor activity",GO:0003690//double-stranded DNA binding;GO:0042802//identical protein binding;GO:0005515//protein binding,K12966//Cytosolic DNA-sensing pathway
9448,67,124,0,10,95,24,0,0,26,48,13,1,MAP4K4;mitogen-activated protein kinase kinase kinase kinase 4,GO:0005737//cytoplasm,GO:0006468//protein phosphorylation;GO:0050790//regulation of catalytic activity;GO:0046328//regulation of JNK cascade;GO:0035556//intracellular signal transduction,GO:0005524//ATP binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K04407//MAPK signaling pathway
945,0,0,0,0,0,0,32,0,25,0,13,0,CD33;CD33 molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane,GO:0007155//cell adhesion;GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0007267//cell-cell signaling,GO:0004872//receptor activity;GO:0030246//carbohydrate binding;GO:0005515//protein binding,K06473//Hematopoietic cell lineage
9450,0,0,0,0,0,0,20,0,41,0,0,0,LY86;lymphocyte antigen 86,GO:0005615//extracellular space;GO:0005886//plasma membrane,GO:0008283//cell proliferation;GO:0045087//innate immune response;GO:0031666//positive regulation of lipopolysaccharide-mediated signaling pathway;GO:0006959//humoral immune response;GO:0006954//inflammatory response;GO:0006915//apoptotic process,-,K05400//Toll-like receptor signaling pathway;Pertussis;Pathogenic Escherichia coli infection;NF-kappa B signaling pathway;Toxoplasmosis
9451,0,0,0,0,0,11,0,0,4,0,0,0,EIF2AK3;eukaryotic translation initiation factor 2-alpha kinase 3,GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0051260//protein homooligomerization;GO:0010629//negative regulation of gene expression;GO:0001503//ossification;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0031642//negative regulation of myelination;GO:0070059//intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0009967//positive regulation of signal transduction;GO:0032092//positive regulation of protein binding;GO:0006412//translation;GO:0043066//negative regulation of apoptotic process;GO:0019217//regulation of fatty acid metabolic process;GO:0032057//negative regulation of translational initiation in response to stress;GO:0030073//insulin secretion;GO:0045444//fat cell differentiation;GO:0034976//response to endoplasmic reticulum stress;GO:0031018//endocrine pancreas development;GO:0007595//lactation;GO:0019722//calcium-mediated signaling;GO:0032933//SREBP signaling pathway;GO:0006983//ER overload response;GO:0017148//negative regulation of translation;GO:0046777//protein autophosphorylation;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007029//endoplasmic reticulum organization;GO:0001501//skeletal system development;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0030282//bone mineralization;GO:0006468//protein phosphorylation;GO:0002063//chondrocyte development;GO:0048009//insulin-like growth factor receptor signaling pathway;GO:0044267//cellular protein metabolic process,GO:0042802//identical protein binding;GO:0004672//protein kinase activity;GO:0019899//enzyme binding;GO:0005524//ATP binding;GO:0019903//protein phosphatase binding;GO:0004694//eukaryotic translation initiation factor 2alpha kinase activity;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,K08860//Alzheimer's disease;Hepatitis C;Herpes simplex infection;Protein processing in endoplasmic reticulum;Influenza A;Epstein-Barr virus infection;Measles
9452,0,0,0,0,0,0,30,0,70,0,0,0,ITM2A;integral membrane protein 2A,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,-
9453,0,94,0,38,236,9,0,0,16,0,7,0,GGPS1;geranylgeranyl diphosphate synthase 1,GO:0005829//cytosol,GO:0006695//cholesterol biosynthetic process;GO:0033384//geranyl diphosphate biosynthetic process;GO:0045337//farnesyl diphosphate biosynthetic process;GO:0006720//isoprenoid metabolic process;GO:0044281//small molecule metabolic process;GO:0033386//geranylgeranyl diphosphate biosynthetic process,GO:0046872//metal ion binding;GO:0004337//geranyltranstransferase activity;GO:0004311//farnesyltranstransferase activity;GO:0004161//dimethylallyltranstransferase activity,K00804//Biosynthesis of secondary metabolites;Metabolic pathways;Terpenoid backbone biosynthesis
9454,33,0,0,0,1,15,59,1,32,2,1,0,HOMER3;homer homolog 3 (Drosophila),GO:0014069//postsynaptic density;GO:0045178//basal part of cell;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045211//postsynaptic membrane;GO:0030054//cell junction;GO:0005886//plasma membrane,GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0006605//protein targeting,GO:0008022//protein C-terminus binding;GO:0019904//protein domain specific binding;GO:0005515//protein binding,K15010//Glutamatergic synapse
9455,0,32,2,36,342,10,0,0,17,0,0,0,HOMER2;homer homolog 2 (Drosophila),GO:0005634//nucleus;GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0043025//neuronal cell body;GO:0045177//apical part of cell;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0007216//G-protein coupled glutamate receptor signaling pathway;GO:0048148//behavioral response to cocaine;GO:0048875//chemical homeostasis within a tissue;GO:0035584//calcium-mediated signaling using intracellular calcium source,GO:0035256//G-protein coupled glutamate receptor binding;GO:0030160//GKAP/Homer scaffold activity;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0003779//actin binding;GO:0019904//protein domain specific binding,K15010//Glutamatergic synapse
9456,0,0,0,1,11,39,19,0,10,1,8,0,HOMER1;homer homolog 1 (Drosophila),GO:0030424//axon;GO:0005887//integral component of plasma membrane;GO:0043198//dendritic shaft;GO:0030054//cell junction;GO:0043034//costamere;GO:0097481//neuronal postsynaptic density;GO:0045211//postsynaptic membrane;GO:0043025//neuronal cell body;GO:0030018//Z disc;GO:0045177//apical part of cell,GO:0035418//protein localization to synapse;GO:0090279//regulation of calcium ion import;GO:0007623//circadian rhythm;GO:0048875//chemical homeostasis within a tissue;GO:0007268//synaptic transmission;GO:0051592//response to calcium ion;GO:0003009//skeletal muscle contraction;GO:0007206//phospholipase C-activating G-protein coupled glutamate receptor signaling pathway;GO:0051928//positive regulation of calcium ion transport;GO:0048741//skeletal muscle fiber development;GO:0048148//behavioral response to cocaine;GO:0009967//positive regulation of signal transduction;GO:2001257//regulation of cation channel activity;GO:0035094//response to nicotine;GO:2001256//regulation of store-operated calcium entry,GO:0035591//signaling adaptor activity;GO:0046982//protein heterodimerization activity;GO:0042802//identical protein binding;GO:0044325//ion channel binding;GO:0032947//protein complex scaffold;GO:0031802//type 5 metabotropic glutamate receptor binding;GO:0097110//scaffold protein binding,K15010//Glutamatergic synapse
9457,0,0,0,0,0,20,24,0,10,0,0,0,FHL5;four and a half LIM domains 5,GO:0005634//nucleus,GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003713//transcription coactivator activity,K14380//Osteoclast differentiation
9459,0,0,0,0,13,11,0,0,44,0,0,0,ARHGEF6;Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6,GO:0005911//cell-cell junction;GO:0030027//lamellipodium;GO:0005622//intracellular;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0007254//JNK cascade;GO:0032321//positive regulation of Rho GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0030032//lamellipodium assembly;GO:0034329//cell junction assembly;GO:0006915//apoptotic process,GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005096//GTPase activator activity,K05729//Pancreatic cancer;Regulation of actin cytoskeleton
946,0,0,0,0,0,0,16,0,13,0,0,0,SIGLEC6;sialic acid binding Ig-like lectin 6,GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0005576//extracellular region,GO:0007267//cell-cell signaling;GO:0007155//cell adhesion,GO:0030246//carbohydrate binding,-
9462,184,1,2,9,66,0,67,0,18,232,9,597,RASAL2;RAS protein activator like 2,GO:0005737//cytoplasm;GO:0031235//intrinsic component of the cytoplasmic side of the plasma membrane,GO:0032320//positive regulation of Ras GTPase activity;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007165//signal transduction,GO:0005515//protein binding;GO:0005099//Ras GTPase activator activity,K04352//MAPK signaling pathway;Axon guidance
9463,37,20,0,0,1,18,111,13,19,0,0,0,PICK1;protein interacting with PRKCA 1,GO:0030666//endocytic vesicle membrane;GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm;GO:0030054//cell junction;GO:0045202//synapse;GO:0005794//Golgi apparatus;GO:0042734//presynaptic membrane;GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0097481//neuronal postsynaptic density;GO:0045211//postsynaptic membrane;GO:0005737//cytoplasm,"GO:0060292//long term synaptic depression;GO:0007268//synaptic transmission;GO:0006468//protein phosphorylation;GO:0002092//positive regulation of receptor internalization;GO:0045161//neuronal ion channel clustering;GO:0097062//dendritic spine maintenance;GO:0006200//ATP catabolic process;GO:0006890//retrograde vesicle-mediated transport, Golgi to ER;GO:0042149//cellular response to glucose starvation;GO:0034316//negative regulation of Arp2/3 complex-mediated actin nucleation;GO:0036294//cellular response to decreased oxygen levels;GO:0006605//protein targeting;GO:0043045//DNA methylation involved in embryo development;GO:0007205//protein kinase C-activating G-protein coupled receptor signaling pathway;GO:0043113//receptor clustering;GO:0015844//monoamine transport;GO:0021782//glial cell development;GO:0043046//DNA methylation involved in gamete generation",GO:0005080//protein kinase C binding;GO:0016887//ATPase activity;GO:0051015//actin filament binding;GO:0019904//protein domain specific binding;GO:0071933//Arp2/3 complex binding;GO:0019899//enzyme binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0008022//protein C-terminus binding;GO:0005102//receptor binding,-
9464,0,0,0,0,0,14,0,0,19,0,8,211,HAND2;heart and neural crest derivatives expressed 2,GO:0005667//transcription factor complex;GO:0043234//protein complex;GO:0000790//nuclear chromatin,"GO:0003007//heart morphogenesis;GO:0060982//coronary artery morphogenesis;GO:0042475//odontogenesis of dentin-containing tooth;GO:0003357//noradrenergic neuron differentiation;GO:0060536//cartilage morphogenesis;GO:2000763//positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process;GO:0003219//cardiac right ventricle formation;GO:0003253//cardiac neural crest cell migration involved in outflow tract morphogenesis;GO:0061309//cardiac neural crest cell development involved in outflow tract morphogenesis;GO:0001525//angiogenesis;GO:0007507//heart development;GO:0060021//palate development;GO:0006351//transcription, DNA-templated;GO:0048935//peripheral nervous system neuron development;GO:2000679//positive regulation of transcription regulatory region DNA binding;GO:0001967//suckling behavior;GO:0007512//adult heart development;GO:0043392//negative regulation of DNA binding;GO:0061032//visceral serous pericardium development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0010667//negative regulation of cardiac muscle cell apoptotic process;GO:0010463//mesenchymal cell proliferation;GO:0003278//apoptotic process involved in heart morphogenesis;GO:0014032//neural crest cell development;GO:0006915//apoptotic process;GO:0045668//negative regulation of osteoblast differentiation;GO:0061325//cell proliferation involved in outflow tract morphogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0043586//tongue development;GO:0048538//thymus development;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048485//sympathetic nervous system development;GO:0001701//in utero embryonic development;GO:0003266//regulation of secondary heart field cardioblast proliferation;GO:0042733//embryonic digit morphogenesis;GO:0001947//heart looping;GO:2000764//positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis",GO:0044212//transcription regulatory region DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0070888//E-box binding;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008134//transcription factor binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0003713//transcription coactivator activity;GO:0033613//activating transcription factor binding;GO:0003680//AT DNA binding,-
9465,0,48,0,20,21,0,0,0,33,0,0,0,AKAP7;A kinase (PRKA) anchor protein 7,GO:0016328//lateral plasma membrane;GO:0005634//nucleus;GO:0016324//apical plasma membrane;GO:0005829//cytosol;GO:0005886//plasma membrane,GO:1902261//positive regulation of delayed rectifier potassium channel activity;GO:0001508//action potential;GO:0035556//intracellular signal transduction;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0008104//protein localization;GO:0008152//metabolic process;GO:0060306//regulation of membrane repolarization;GO:0071320//cellular response to cAMP;GO:0006811//ion transport,GO:0003824//catalytic activity;GO:0051018//protein kinase A binding;GO:0019901//protein kinase binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,-
9466,59,0,0,0,0,0,0,0,18,0,8,0,"IL27RA;interleukin 27 receptor, alpha",GO:0005887//integral component of plasma membrane,GO:0050830//defense response to Gram-positive bacterium;GO:0032729//positive regulation of interferon-gamma production;GO:0048302//regulation of isotype switching to IgG isotypes;GO:0070106//interleukin-27-mediated signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0002829//negative regulation of type 2 immune response;GO:0002827//positive regulation of T-helper 1 type immune response;GO:0006955//immune response,GO:0045509//interleukin-27 receptor activity;GO:0004888//transmembrane signaling receptor activity,K05064//Cytokine-cytokine receptor interaction;Jak-STAT signaling pathway
9467,0,0,0,1,0,0,9,0,71,0,0,0,SH3BP5;SH3-domain binding protein 5 (BTK-associated),GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0006469//negative regulation of protein kinase activity;GO:0035556//intracellular signal transduction,GO:0017124//SH3 domain binding;GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity,K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy
9468,0,0,0,0,0,0,19,0,35,0,9,0,"PCYT1B;phosphate cytidylyltransferase 1, choline, beta",GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0006644//phospholipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0001541//ovarian follicle development;GO:0044281//small molecule metabolic process;GO:0006656//phosphatidylcholine biosynthetic process;GO:0007283//spermatogenesis;GO:0006657//CDP-choline pathway,GO:0004105//choline-phosphate cytidylyltransferase activity,K00968//Glycerophospholipid metabolism;Phosphonate and phosphinate metabolism;Metabolic pathways
9469,32,0,0,0,0,37,3,3,52,0,27,0,CHST3;carbohydrate (chondroitin 6) sulfotransferase 3,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0006790//sulfur compound metabolic process;GO:0030206//chondroitin sulfate biosynthetic process;GO:0005975//carbohydrate metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0030204//chondroitin sulfate metabolic process;GO:0043029//T cell homeostasis,GO:0050698//proteoglycan sulfotransferase activity;GO:0008459//chondroitin 6-sulfotransferase activity;GO:0008146//sulfotransferase activity,K01020//Glycosaminoglycan biosynthesis - chondroitin sulfate
947,0,0,0,0,0,0,0,26,19,0,0,0,CD34;CD34 molecule,GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0036053//glomerular endothelium fenestra;GO:0045171//intercellular bridge;GO:0048471//perinuclear region of cytoplasm;GO:0005764//lysosome;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane,GO:0003158//endothelium development;GO:0010629//negative regulation of gene expression;GO:0001935//endothelial cell proliferation;GO:0072254//metanephric glomerular mesangial cell differentiation;GO:0061042//vascular wound healing;GO:0001894//tissue homeostasis;GO:0016337//single organismal cell-cell adhesion;GO:0060290//transdifferentiation;GO:0010628//positive regulation of gene expression;GO:0006536//glutamate metabolic process;GO:1901215//negative regulation of neuron death;GO:0008283//cell proliferation;GO:0072011//glomerular endothelium development;GO:1900168//positive regulation of glial cell line-derived neurotrophic factor secretion;GO:2001214//positive regulation of vasculogenesis;GO:0050776//regulation of immune response;GO:0045019//negative regulation of nitric oxide biosynthetic process;GO:0072089//stem cell proliferation;GO:0048870//cell motility;GO:0030195//negative regulation of blood coagulation;GO:0030097//hemopoiesis;GO:0032720//negative regulation of tumor necrosis factor production;GO:1900035//negative regulation of cellular response to heat;GO:0045766//positive regulation of angiogenesis;GO:0038001//paracrine signaling;GO:0035759//mesangial cell-matrix adhesion;GO:0071636//positive regulation of transforming growth factor beta production;GO:0032733//positive regulation of interleukin-10 production;GO:1900038//negative regulation of cellular response to hypoxia;GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0071971//extracellular vesicular exosome assembly;GO:0003094//glomerular filtration;GO:1900041//negative regulation of interleukin-2 secretion;GO:0008217//regulation of blood pressure;GO:0071657//positive regulation of granulocyte colony-stimulating factor production;GO:0042482//positive regulation of odontogenesis;GO:0071425//hematopoietic stem cell proliferation,GO:0008134//transcription factor binding;GO:0030246//carbohydrate binding;GO:0043199//sulfate binding,K06474//Cell adhesion molecules (CAMs);Hematopoietic cell lineage
9470,78,1,0,1,36,0,0,0,0,0,0,0,EIF4E2;eukaryotic translation initiation factor 4E family member 2,GO:0005829//cytosol;GO:0005845//mRNA cap binding complex,GO:0001701//in utero embryonic development;GO:0006413//translational initiation;GO:0017148//negative regulation of translation;GO:0019221//cytokine-mediated signaling pathway,"GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0008135//translation factor activity, nucleic acid binding;GO:0003743//translation initiation factor activity;GO:0000339//RNA cap binding",K03259//Insulin signaling pathway;mTOR signaling pathway;RNA transport
9472,66,0,0,0,0,40,31,0,79,0,0,0,AKAP6;A kinase (PRKA) anchor protein 6,GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0030315//T-tubule;GO:0014704//intercalated disc;GO:0014701//junctional sarcoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0034704//calcium channel complex;GO:0005635//nuclear envelope;GO:0005901//caveola;GO:0016529//sarcoplasmic reticulum,GO:0051533//positive regulation of NFAT protein import into nucleus;GO:0032514//positive regulation of protein phosphatase type 2B activity;GO:0071320//cellular response to cAMP;GO:0030818//negative regulation of cAMP biosynthetic process;GO:1902261//positive regulation of delayed rectifier potassium channel activity;GO:0071345//cellular response to cytokine stimulus;GO:0010738//regulation of protein kinase A signaling;GO:0060306//regulation of membrane repolarization;GO:0006605//protein targeting;GO:0070886//positive regulation of calcineurin-NFAT signaling cascade;GO:1901381//positive regulation of potassium ion transmembrane transport;GO:0019933//cAMP-mediated signaling;GO:0061051//positive regulation of cell growth involved in cardiac muscle cell development;GO:0030307//positive regulation of cell growth;GO:0010880//regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0001508//action potential;GO:0051281//positive regulation of release of sequestered calcium ion into cytosol;GO:0060316//positive regulation of ryanodine-sensitive calcium-release channel activity,GO:0005515//protein binding;GO:0034237//protein kinase A regulatory subunit binding;GO:0044325//ion channel binding;GO:0008179//adenylate cyclase binding;GO:0051018//protein kinase A binding;GO:0032947//protein complex scaffold;GO:0043495//protein anchor,K16072//NF-kappa B signaling pathway
9473,0,0,0,0,0,29,0,1,39,2,17,0,THEMIS2;thymocyte selection associated family member 2,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0050852//T cell receptor signaling pathway;GO:0007155//cell adhesion;GO:0006954//inflammatory response,-,-
9474,0,85,0,31,98,38,75,0,42,0,0,0,ATG5;autophagy related 5,GO:0016020//membrane;GO:0034045//pre-autophagosomal structure membrane;GO:0005776//autophagic vacuole;GO:0005930//axoneme;GO:0005737//cytoplasm,GO:0039689//negative stranded viral RNA replication;GO:0043066//negative regulation of apoptotic process;GO:0060047//heart contraction;GO:0042493//response to drug;GO:0045087//innate immune response;GO:0001974//blood vessel remodeling;GO:0032480//negative regulation of type I interferon production;GO:0048840//otolith development;GO:0006914//autophagy;GO:0006915//apoptotic process;GO:0042311//vasodilation;GO:0031397//negative regulation of protein ubiquitination;GO:1902017//regulation of cilium assembly;GO:0043687//post-translational protein modification;GO:0000045//autophagic vacuole assembly;GO:0009620//response to fungus;GO:0055015//ventricular cardiac muscle cell development;GO:0002739//regulation of cytokine secretion involved in immune response,GO:0005515//protein binding,K08339//Shigellosis;RIG-I-like receptor signaling pathway;Regulation of autophagy
9475,104,0,0,61,106,26,12,89,89,0,28,222,"ROCK2;Rho-associated, coiled-coil containing protein kinase 2",GO:0005634//nucleus;GO:0005813//centrosome;GO:0005886//plasma membrane;GO:0031616//spindle pole centrosome;GO:0005829//cytosol,GO:0048511//rhythmic process;GO:0051298//centrosome duplication;GO:0006939//smooth muscle contraction;GO:0016525//negative regulation of angiogenesis;GO:0000910//cytokinesis;GO:0001843//neural tube closure;GO:2000145//regulation of cell motility;GO:0051893//regulation of focal adhesion assembly;GO:0030155//regulation of cell adhesion;GO:0010825//positive regulation of centrosome duplication;GO:0042752//regulation of circadian rhythm;GO:2000114//regulation of establishment of cell polarity;GO:0006468//protein phosphorylation;GO:0045616//regulation of keratinocyte differentiation;GO:0051492//regulation of stress fiber assembly;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0030036//actin cytoskeleton organization;GO:0007411//axon guidance;GO:0035556//intracellular signal transduction;GO:0032956//regulation of actin cytoskeleton organization,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0044822//poly(A) RNA binding;GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0005198//structural molecule activity;GO:0017048//Rho GTPase binding,K04514//Pathogenic Escherichia coli infection;Focal adhesion;Vascular smooth muscle contraction;Wnt signaling pathway;Regulation of actin cytoskeleton;Shigellosis;Leukocyte transendothelial migration;TGF-beta signaling pathway;Chemokine signaling pathway;Axon guidance;Salmonella infection
9476,0,0,0,0,16,0,0,0,10,0,0,0,NAPSA;napsin A aspartic peptidase,GO:0005764//lysosome;GO:0097208//alveolar lamellar body;GO:0005615//extracellular space;GO:0070062//extracellular vesicular exosome,GO:0043129//surfactant homeostasis;GO:0033619//membrane protein proteolysis;GO:0006508//proteolysis,GO:0008233//peptidase activity;GO:0004190//aspartic-type endopeptidase activity;GO:0004175//endopeptidase activity,K08565//Lysosome
9477,0,34,0,9,32,0,5,0,26,0,0,0,MED20;mediator complex subunit 20,GO:0005654//nucleoplasm;GO:0016592//mediator complex,"GO:0010467//gene expression;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0005515//protein binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0001104//RNA polymerase II transcription cofactor activity,-
9478,0,0,0,0,0,0,0,0,16,0,10,1,CABP1;calcium binding protein 1,GO:0005938//cell cortex;GO:0043025//neuronal cell body;GO:0043234//protein complex;GO:0014069//postsynaptic density;GO:0030054//cell junction;GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0005615//extracellular space,GO:0042308//negative regulation of protein import into nucleus;GO:1901386//negative regulation of voltage-gated calcium channel activity;GO:0043086//negative regulation of catalytic activity;GO:0010651//negative regulation of cell communication by electrical coupling,GO:0031800//type 3 metabotropic glutamate receptor binding;GO:0019904//protein domain specific binding;GO:0048306//calcium-dependent protein binding;GO:0005509//calcium ion binding;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0044325//ion channel binding;GO:0008139//nuclear localization sequence binding;GO:0004857//enzyme inhibitor activity,K02183//Salivary secretion;Olfactory transduction;Calcium signaling pathway;Melanogenesis;Glioma;Gastric acid secretion;Alzheimer's disease;Neurotrophin signaling pathway;Long-term potentiation;Pertussis;Tuberculosis;Alcoholism;Phototransduction;Insulin signaling pathway;Dopaminergic synapse;Phosphatidylinositol signaling system;GnRH signaling pathway;Plant-pathogen interaction;Phototransduction - fly;Oocyte meiosis;Vascular smooth muscle contraction;Amphetamine addiction
9479,58,0,1,0,2,14,0,1,35,0,0,0,MAPK8IP1;mitogen-activated protein kinase 8 interacting protein 1,GO:0031966//mitochondrial membrane;GO:0005829//cytosol;GO:0044294//dendritic growth cone;GO:0005789//endoplasmic reticulum membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus;GO:0044302//dentate gyrus mossy fiber;GO:0045202//synapse;GO:0044297//cell body;GO:0044295//axonal growth cone;GO:0005737//cytoplasm,"GO:2001243//negative regulation of intrinsic apoptotic signaling pathway;GO:0043508//negative regulation of JUN kinase activity;GO:0007258//JUN phosphorylation;GO:0046328//regulation of JNK cascade;GO:0043066//negative regulation of apoptotic process;GO:0046329//negative regulation of JNK cascade;GO:0016192//vesicle-mediated transport;GO:0006355//regulation of transcription, DNA-templated;GO:0009967//positive regulation of signal transduction",GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005078//MAP-kinase scaffold activity;GO:0042802//identical protein binding;GO:0031434//mitogen-activated protein kinase kinase binding;GO:0008432//JUN kinase binding;GO:0005515//protein binding;GO:0004860//protein kinase inhibitor activity;GO:0019894//kinesin binding,K04434//MAPK signaling pathway
948,0,0,0,0,0,10,0,0,29,0,0,0,CD36;CD36 molecule (thrombospondin receptor),GO:0005615//extracellular space;GO:0030666//endocytic vesicle membrane;GO:0005887//integral component of plasma membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0045121//membrane raft;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0045335//phagocytic vesicle;GO:0005794//Golgi apparatus;GO:0031092//platelet alpha granule membrane,"GO:0044255//cellular lipid metabolic process;GO:0044130//negative regulation of growth of symbiont in host;GO:0010886//positive regulation of cholesterol storage;GO:0035634//response to stilbenoid;GO:0034134//toll-like receptor 2 signaling pathway;GO:0042953//lipoprotein transport;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0060100//positive regulation of phagocytosis, engulfment;GO:0015911//plasma membrane long-chain fatty acid transport;GO:0032760//positive regulation of tumor necrosis factor production;GO:0044281//small molecule metabolic process;GO:0034381//plasma lipoprotein particle clearance;GO:0002224//toll-like receptor signaling pathway;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0043277//apoptotic cell clearance;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0032755//positive regulation of interleukin-6 production;GO:0071221//cellular response to bacterial lipopeptide;GO:0006898//receptor-mediated endocytosis;GO:0034383//low-density lipoprotein particle clearance;GO:2000379//positive regulation of reactive oxygen species metabolic process;GO:0045087//innate immune response;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0006629//lipid metabolic process;GO:2000334//positive regulation of blood microparticle formation;GO:0010744//positive regulation of macrophage derived foam cell differentiation;GO:0043410//positive regulation of MAPK cascade;GO:0060907//positive regulation of macrophage cytokine production;GO:0006910//phagocytosis, recognition;GO:0071223//cellular response to lipoteichoic acid;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0071447//cellular response to hydroperoxide;GO:2000121//regulation of removal of superoxide radicals;GO:0001954//positive regulation of cell-matrix adhesion;GO:0034142//toll-like receptor 4 signaling pathway;GO:0044539//long-chain fatty acid import;GO:0030194//positive regulation of blood coagulation;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0050830//defense response to Gram-positive bacterium;GO:0019934//cGMP-mediated signaling;GO:0042992//negative regulation of transcription factor import into nucleus;GO:0071222//cellular response to lipopolysaccharide;GO:0055096//low-density lipoprotein particle mediated signaling;GO:0030168//platelet activation;GO:0030301//cholesterol transport;GO:0007596//blood coagulation;GO:0032735//positive regulation of interleukin-12 production;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0007263//nitric oxide mediated signal transduction;GO:0007155//cell adhesion;GO:0019915//lipid storage;GO:0002576//platelet degranulation",GO:0008289//lipid binding;GO:0070053//thrombospondin receptor activity;GO:0008035//high-density lipoprotein particle binding;GO:0050431//transforming growth factor beta binding;GO:0071813//lipoprotein particle binding;GO:0070892//lipoteichoic acid receptor activity;GO:0030169//low-density lipoprotein particle binding;GO:0005041//low-density lipoprotein receptor activity,K06259//Malaria;Adipocytokine signaling pathway;PPAR signaling pathway;ECM-receptor interaction;Phagosome;Hematopoietic cell lineage;Fat digestion and absorption
9480,67,0,0,0,0,10,37,0,60,0,4,0,ONECUT2;one cut homeobox 2,GO:0005634//nucleus,"GO:0009887//organ morphogenesis;GO:0042384//cilium assembly;GO:0030335//positive regulation of cell migration;GO:0001952//regulation of cell-matrix adhesion;GO:0048935//peripheral nervous system neuron development;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006351//transcription, DNA-templated;GO:0001889//liver development;GO:0031018//endocrine pancreas development;GO:0002064//epithelial cell development;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045165//cell fate commitment",GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding,K08026//Maturity onset diabetes of the young
9481,0,0,0,0,0,40,53,1,31,0,0,0,"SLC25A27;solute carrier family 25, member 27",GO:0005743//mitochondrial inner membrane;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0043025//neuronal cell body;GO:0045177//apical part of cell,GO:0048839//inner ear development;GO:0070997//neuron death;GO:0008284//positive regulation of cell proliferation;GO:0035356//cellular triglyceride homeostasis;GO:0051562//negative regulation of mitochondrial calcium ion concentration;GO:0043066//negative regulation of apoptotic process;GO:0046324//regulation of glucose import;GO:0006810//transport;GO:0006091//generation of precursor metabolites and energy;GO:0010917//negative regulation of mitochondrial membrane potential,-,-
9482,0,1,0,0,11,0,0,0,0,0,0,0,STX8;syntaxin 8,GO:0005783//endoplasmic reticulum;GO:0031201//SNARE complex;GO:0005887//integral component of plasma membrane;GO:0005765//lysosomal membrane;GO:0031902//late endosome membrane,GO:0006906//vesicle fusion;GO:0006810//transport;GO:0008333//endosome to lysosome transport;GO:0006886//intracellular protein transport,GO:0005484//SNAP receptor activity;GO:0031625//ubiquitin protein ligase binding,K08501//SNARE interactions in vesicular transport
9486,0,0,0,0,0,10,14,0,0,0,0,0,CHST10;carbohydrate sulfotransferase 10,GO:0005794//Golgi apparatus;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0016051//carbohydrate biosynthetic process;GO:0007616//long-term memory;GO:0007612//learning;GO:0007155//cell adhesion,GO:0008146//sulfotransferase activity;GO:0016232//HNK-1 sulfotransferase activity,K09674//Other types of O-glycan biosynthesis
9487,0,0,0,0,0,0,0,0,12,0,0,0,"PIGL;phosphatidylinositol glycan anchor biosynthesis, class L",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0016254//preassembly of GPI anchor in ER membrane;GO:0043687//post-translational protein modification;GO:0006506//GPI anchor biosynthetic process;GO:0044267//cellular protein metabolic process;GO:0006501//C-terminal protein lipidation,GO:0000225//N-acetylglucosaminylphosphatidylinositol deacetylase activity,K03434//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
9488,7,33,0,45,16,0,0,0,36,0,78,0,"PIGB;phosphatidylinositol glycan anchor biosynthesis, class B",GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0097502//mannosylation;GO:0006501//C-terminal protein lipidation;GO:0044267//cellular protein metabolic process;GO:0006506//GPI anchor biosynthetic process;GO:0043687//post-translational protein modification;GO:0016254//preassembly of GPI anchor in ER membrane,GO:0000030//mannosyltransferase activity,K05286//Glycosylphosphatidylinositol(GPI)-anchor biosynthesis;Metabolic pathways
9489,15,0,0,0,0,32,0,40,32,0,0,0,PGS1;phosphatidylglycerophosphate synthase 1,GO:0005743//mitochondrial inner membrane;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion,GO:0046474//glycerophospholipid biosynthetic process;GO:0046339//diacylglycerol metabolic process;GO:0006644//phospholipid metabolic process;GO:0032049//cardiolipin biosynthetic process;GO:0044281//small molecule metabolic process;GO:0006655//phosphatidylglycerol biosynthetic process,GO:0008444//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity;GO:0005524//ATP binding;GO:0005509//calcium ion binding,K00995//Shigellosis;Glycerophospholipid metabolism;Metabolic pathways
949,0,0,0,0,0,7,0,59,47,0,23,0,"SCARB1;scavenger receptor class B, member 1",GO:0030666//endocytic vesicle membrane;GO:0031528//microvillus membrane;GO:0005901//caveola;GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0009986//cell surface;GO:0005765//lysosomal membrane,GO:0010867//positive regulation of triglyceride biosynthetic process;GO:0051000//positive regulation of nitric-oxide synthase activity;GO:0006898//receptor-mediated endocytosis;GO:0042632//cholesterol homeostasis;GO:0015914//phospholipid transport;GO:0034384//high-density lipoprotein particle clearance;GO:0044406//adhesion of symbiont to host;GO:0007155//cell adhesion;GO:0034383//low-density lipoprotein particle clearance;GO:0050764//regulation of phagocytosis;GO:0042157//lipoprotein metabolic process;GO:0010899//regulation of phosphatidylcholine catabolic process;GO:0043534//blood vessel endothelial cell migration;GO:0016032//viral process;GO:0070508//cholesterol import;GO:0031663//lipopolysaccharide-mediated signaling pathway;GO:0034375//high-density lipoprotein particle remodeling;GO:0006707//cholesterol catabolic process;GO:0070328//triglyceride homeostasis;GO:0042060//wound healing;GO:0043691//reverse cholesterol transport;GO:0010595//positive regulation of endothelial cell migration;GO:0043654//recognition of apoptotic cell;GO:0001935//endothelial cell proliferation;GO:0032497//detection of lipopolysaccharide;GO:0010886//positive regulation of cholesterol storage;GO:0015920//lipopolysaccharide transport;GO:0044281//small molecule metabolic process;GO:0006702//androgen biosynthetic process;GO:0033344//cholesterol efflux,GO:0005545//1-phosphatidylinositol binding;GO:0008035//high-density lipoprotein particle binding;GO:0001786//phosphatidylserine binding;GO:0001530//lipopolysaccharide binding;GO:0042803//protein homodimerization activity;GO:0001875//lipopolysaccharide receptor activity;GO:0005515//protein binding;GO:0030169//low-density lipoprotein particle binding;GO:0005215//transporter activity;GO:0034186//apolipoprotein A-I binding;GO:0070506//high-density lipoprotein particle receptor activity;GO:0034185//apolipoprotein binding,K13885//Bile secretion;Fat digestion and absorption;Hepatitis C;Phagosome;Vitamin digestion and absorption
9491,37,1,0,8,56,2,0,0,14,83,12,0,"PSMF1;proteasome (prosome, macropain) inhibitor subunit 1 (PI31)",GO:0005839//proteasome core complex;GO:0005829//cytosol;GO:0005783//endoplasmic reticulum;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,"GO:0010951//negative regulation of endopeptidase activity;GO:0006915//apoptotic process;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0034641//cellular nitrogen compound metabolic process;GO:0000278//mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0016032//viral process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0010467//gene expression;GO:0043066//negative regulation of apoptotic process;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:1901799//negative regulation of proteasomal protein catabolic process;GO:0044281//small molecule metabolic process",GO:0005515//protein binding;GO:0070628//proteasome binding;GO:0004866//endopeptidase inhibitor activity,K06700//Proteasome
9493,22,0,0,0,0,0,40,0,40,0,0,0,KIF23;kinesin family member 23,GO:0005634//nucleus;GO:0005874//microtubule;GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0005871//kinesin complex;GO:0005829//cytosol;GO:0005813//centrosome;GO:0097149//centralspindlin complex;GO:0005819//spindle;GO:0005654//nucleoplasm;GO:0072686//mitotic spindle,GO:0006200//ATP catabolic process;GO:0007018//microtubule-based movement;GO:0032467//positive regulation of cytokinesis;GO:0000910//cytokinesis;GO:0000022//mitotic spindle elongation;GO:0000278//mitotic cell cycle;GO:0008152//metabolic process;GO:0051256//spindle midzone assembly involved in mitosis;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0007596//blood coagulation,GO:0005524//ATP binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding;GO:0005515//protein binding,-
9495,94,0,0,7,0,32,1,0,41,163,0,0,AKAP5;A kinase (PRKA) anchor protein 5,GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0006112//energy reserve metabolic process;GO:0050796//regulation of insulin secretion;GO:0030819//positive regulation of cAMP biosynthetic process;GO:0007268//synaptic transmission;GO:0006605//protein targeting;GO:0007165//signal transduction;GO:0044281//small molecule metabolic process;GO:0010739//positive regulation of protein kinase A signaling,GO:0008179//adenylate cyclase binding;GO:0051018//protein kinase A binding;GO:0005516//calmodulin binding;GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
9496,0,0,0,0,0,0,0,0,19,73,0,0,TBX4;T-box 4,GO:0005634//nucleus,"GO:0048705//skeletal system morphogenesis;GO:0001525//angiogenesis;GO:0006355//regulation of transcription, DNA-templated;GO:0030326//embryonic limb morphogenesis;GO:0007275//multicellular organismal development;GO:0035108//limb morphogenesis;GO:0030324//lung development;GO:0006351//transcription, DNA-templated;GO:0002009//morphogenesis of an epithelium",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
9497,0,0,0,11,1,27,71,0,66,51,18,0,"SLC4A7;solute carrier family 4, sodium bicarbonate cotransporter, member 7",GO:0032420//stereocilium;GO:0016324//apical plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:0061299//retina vasculature morphogenesis in camera-type eye;GO:0060117//auditory receptor cell development;GO:0015701//bicarbonate transport;GO:0021747//cochlear nucleus development;GO:0035725//sodium ion transmembrane transport;GO:0055085//transmembrane transport;GO:0046666//retinal cell programmed cell death;GO:0006811//ion transport,GO:0005452//inorganic anion exchanger activity;GO:0008510//sodium:bicarbonate symporter activity,-
9498,0,0,0,0,0,68,156,0,110,139,9,0,"SLC4A8;solute carrier family 4, sodium bicarbonate cotransporter, member 8",GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0016021//integral component of membrane;GO:0032809//neuronal cell body membrane,GO:0015701//bicarbonate transport;GO:0055085//transmembrane transport;GO:0006814//sodium ion transport;GO:0006811//ion transport,GO:0005452//inorganic anion exchanger activity,-
9499,0,0,0,0,0,0,0,0,0,0,21,0,MYOT;myotilin,GO:0030018//Z disc;GO:0015629//actin cytoskeleton;GO:0042383//sarcolemma,GO:0006936//muscle contraction,GO:0005515//protein binding;GO:0008307//structural constituent of muscle;GO:0003779//actin binding,K12567//Dilated cardiomyopathy;Hypertrophic cardiomyopathy (HCM)
95,0,0,0,0,0,0,0,0,13,0,0,0,ACY1;aminoacylase 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0006508//proteolysis;GO:0006520//cellular amino acid metabolic process,GO:0004046//aminoacylase activity;GO:0046872//metal ion binding;GO:0008237//metallopeptidase activity,K14677//Metabolic pathways;Biosynthesis of secondary metabolites;Arginine and proline metabolism
950,0,13,0,11,52,0,31,0,14,265,0,0,"SCARB2;scavenger receptor class B, member 2",GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005765//lysosomal membrane;GO:0043202//lysosomal lumen,GO:0006622//protein targeting to lysosome;GO:0007155//cell adhesion,GO:0004872//receptor activity;GO:0019899//enzyme binding;GO:0005515//protein binding,K12384//Lysosome
9500,7,2,1,17,46,14,0,2,46,125,2,0,"MAGED1;melanoma antigen family D, 1",GO:0005886//plasma membrane;GO:0043234//protein complex;GO:0000785//chromatin;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:2001235//positive regulation of apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0097190//apoptotic signaling pathway;GO:0090190//positive regulation of branching involved in ureteric bud morphogenesis;GO:0032922//circadian regulation of gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006915//apoptotic process;GO:0042752//regulation of circadian rhythm;GO:0043406//positive regulation of MAP kinase activity;GO:0050680//negative regulation of epithelial cell proliferation;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006355//regulation of transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0042981//regulation of apoptotic process",GO:0005515//protein binding;GO:0003713//transcription coactivator activity,K12464//Neurotrophin signaling pathway
9501,101,0,0,0,0,25,0,48,0,241,17,0,RPH3AL;rabphilin 3A-like (without C2 domains),GO:0030667//secretory granule membrane;GO:0005737//cytoplasm;GO:0030658//transport vesicle membrane,GO:0042593//glucose homeostasis;GO:0006887//exocytosis;GO:0042493//response to drug;GO:0045744//negative regulation of G-protein coupled receptor protein signaling pathway;GO:0050714//positive regulation of protein secretion;GO:0017158//regulation of calcium ion-dependent exocytosis;GO:0006886//intracellular protein transport,GO:0046872//metal ion binding;GO:0030274//LIM domain binding;GO:0008092//cytoskeletal protein binding;GO:0017137//Rab GTPase binding,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
9502,0,0,0,0,0,2,0,0,0,0,0,0,"XAGE2;X antigen family, member 2",-,-,-,-
9507,0,0,0,0,0,0,0,68,62,0,2,0,"ADAMTS4;ADAM metallopeptidase with thrombospondin type 1 motif, 4",GO:0031012//extracellular matrix;GO:0005578//proteinaceous extracellular matrix;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0042742//defense response to bacterium;GO:0006508//proteolysis;GO:0001501//skeletal system development;GO:0030198//extracellular matrix organization;GO:0022617//extracellular matrix disassembly,GO:0005515//protein binding;GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity;GO:0008233//peptidase activity;GO:0002020//protease binding,-
9508,0,0,23,1,0,24,39,13,36,0,0,156,"ADAMTS3;ADAM metallopeptidase with thrombospondin type 1 motif, 3",GO:0005615//extracellular space;GO:0005576//extracellular region;GO:0070062//extracellular vesicular exosome;GO:0005578//proteinaceous extracellular matrix;GO:0031012//extracellular matrix,GO:0030198//extracellular matrix organization;GO:0043206//extracellular fibril organization;GO:0016485//protein processing;GO:0032964//collagen biosynthetic process;GO:0030199//collagen fibril organization;GO:0030574//collagen catabolic process;GO:0006508//proteolysis;GO:1900748//positive regulation of vascular endothelial growth factor signaling pathway;GO:0010573//vascular endothelial growth factor production,GO:0004175//endopeptidase activity;GO:0004222//metalloendopeptidase activity;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0008201//heparin binding,-
9509,0,25,0,0,5,16,46,132,106,0,2,0,"ADAMTS2;ADAM metallopeptidase with thrombospondin type 1 motif, 2",GO:0005576//extracellular region;GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis;GO:0007283//spermatogenesis;GO:0030324//lung development;GO:0043588//skin development;GO:0030574//collagen catabolic process;GO:0030199//collagen fibril organization;GO:0030198//extracellular matrix organization;GO:0016485//protein processing,GO:0008237//metallopeptidase activity;GO:0008270//zinc ion binding;GO:0004222//metalloendopeptidase activity,-
9510,0,1,0,33,133,0,13,140,58,0,16,1,"ADAMTS1;ADAM metallopeptidase with thrombospondin type 1 motif, 1",GO:0005604//basement membrane;GO:0031410//cytoplasmic vesicle;GO:0005737//cytoplasm,GO:0006508//proteolysis;GO:0008285//negative regulation of cell proliferation;GO:0007229//integrin-mediated signaling pathway;GO:0001822//kidney development;GO:0001542//ovulation from ovarian follicle;GO:0060347//heart trabecula formation,GO:0004222//metalloendopeptidase activity;GO:0008201//heparin binding;GO:0008270//zinc ion binding;GO:0008237//metallopeptidase activity,-
9512,0,0,0,45,62,0,0,0,32,0,22,0,PMPCB;peptidase (mitochondrial processing) beta,GO:0005743//mitochondrial inner membrane;GO:0005759//mitochondrial matrix,GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis;GO:0006626//protein targeting to mitochondrion,GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
9513,9,26,0,2,50,10,0,0,31,0,5,0,"FXR2;fragile X mental retardation, autosomal homolog 2",GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0022625//cytosolic large ribosomal subunit;GO:0005737//cytoplasm,-,GO:0003723//RNA binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K15516//RNA transport
9514,0,0,0,0,0,0,15,0,15,0,3,0,GAL3ST1;galactose-3-O-sulfotransferase 1,GO:0005887//integral component of plasma membrane;GO:0000139//Golgi membrane;GO:0016020//membrane,GO:0007283//spermatogenesis;GO:0006687//glycosphingolipid metabolic process;GO:0006487//protein N-linked glycosylation;GO:0006682//galactosylceramide biosynthetic process;GO:0044281//small molecule metabolic process;GO:0042552//myelination;GO:0006665//sphingolipid metabolic process,GO:0008146//sulfotransferase activity;GO:0001733//galactosylceramide sulfotransferase activity,K01019//Metabolic pathways;Sphingolipid metabolism
9515,9,1,0,34,1,41,1,0,77,0,0,0,STXBP5L;syntaxin binding protein 5-like,GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm,GO:0015031//protein transport;GO:0046676//negative regulation of insulin secretion;GO:0050714//positive regulation of protein secretion;GO:0042593//glucose homeostasis;GO:0006887//exocytosis;GO:0017157//regulation of exocytosis,GO:0019905//syntaxin binding,-
9516,0,27,1,44,206,4,0,0,2,0,0,0,LITAF;lipopolysaccharide-induced TNF factor,GO:0005765//lysosomal membrane;GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,"GO:0006915//apoptotic process;GO:0006351//transcription, DNA-templated;GO:0001817//regulation of cytokine production;GO:0007568//aging;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0071222//cellular response to lipopolysaccharide;GO:0042347//negative regulation of NF-kappaB import into nucleus;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0007165//signal transduction",GO:0005515//protein binding;GO:0004871//signal transducer activity;GO:0050699//WW domain binding,-
9517,0,0,0,0,11,0,34,0,39,0,15,0,"SPTLC2;serine palmitoyltransferase, long chain base subunit 2",GO:0017059//serine C-palmitoyltransferase complex;GO:0016021//integral component of membrane;GO:0005739//mitochondrion;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0006686//sphingomyelin biosynthetic process;GO:0030148//sphingolipid biosynthetic process;GO:0046511//sphinganine biosynthetic process;GO:0046512//sphingosine biosynthetic process;GO:0006665//sphingolipid metabolic process;GO:0046513//ceramide biosynthetic process,GO:0004758//serine C-palmitoyltransferase activity;GO:0030170//pyridoxal phosphate binding,K00654//Metabolic pathways;Sphingolipid metabolism
9518,0,0,0,0,0,0,0,68,0,0,0,0,GDF15;growth differentiation factor 15,GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0005615//extracellular space,GO:0007267//cell-cell signaling;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007165//signal transduction,GO:0008083//growth factor activity;GO:0005125//cytokine activity,-
9519,9,0,0,17,40,5,0,70,0,0,0,0,TBPL1;TBP-like 1,GO:0005737//cytoplasm;GO:0005672//transcription factor TFIIA complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006352//DNA-templated transcription, initiation;GO:0006366//transcription from RNA polymerase II promoter;GO:0007289//spermatid nucleus differentiation;GO:0006235//dTTP biosynthetic process;GO:0001675//acrosome assembly",GO:0003713//transcription coactivator activity;GO:0003677//DNA binding,K03120//HTLV-I infection;Huntington's disease;Herpes simplex infection;Basal transcription factors;Epstein-Barr virus infection
952,96,0,0,9,0,0,0,0,0,0,0,0,CD38;CD38 molecule,GO:0005634//nucleus;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0009986//cell surface;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,"GO:0050853//B cell receptor signaling pathway;GO:0030890//positive regulation of B cell proliferation;GO:0007565//female pregnancy;GO:0042493//response to drug;GO:0007204//positive regulation of cytosolic calcium ion concentration;GO:0045893//positive regulation of transcription, DNA-templated;GO:0008152//metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0030307//positive regulation of cell growth;GO:0045779//negative regulation of bone resorption;GO:0032355//response to estradiol;GO:0032570//response to progesterone;GO:0007165//signal transduction;GO:0032526//response to retinoic acid;GO:0070555//response to interleukin-1;GO:0032024//positive regulation of insulin secretion;GO:0097190//apoptotic signaling pathway;GO:0045907//positive regulation of vasoconstriction;GO:0033194//response to hydroperoxide;GO:0060292//long term synaptic depression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0001666//response to hypoxia",GO:0003953//NAD+ nucleosidase activity;GO:0016849//phosphorus-oxygen lyase activity;GO:0050135//NAD(P)+ nucleosidase activity;GO:0016740//transferase activity,K01242//Calcium signaling pathway;Pancreatic secretion;Epstein-Barr virus infection;Salivary secretion;Nicotinate and nicotinamide metabolism;Metabolic pathways;Hematopoietic cell lineage
9520,54,102,114,62,262,0,28,0,51,0,70,0,NPEPPS;aminopeptidase puromycin sensitive,GO:0005634//nucleus;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome,GO:0071456//cellular response to hypoxia;GO:0006508//proteolysis;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0000209//protein polyubiquitination,GO:0008237//metallopeptidase activity;GO:0004177//aminopeptidase activity;GO:0008270//zinc ion binding,-
9521,0,17,0,5,6,0,0,1,0,0,0,0,EEF1E1;eukaryotic translation elongation factor 1 epsilon 1,GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0043517//positive regulation of DNA damage response, signal transduction by p53 class mediator;GO:0043065//positive regulation of apoptotic process;GO:0006418//tRNA aminoacylation for protein translation;GO:0008285//negative regulation of cell proliferation;GO:0010467//gene expression",GO:0005515//protein binding,-
9522,71,0,0,4,40,12,26,0,37,0,0,0,SCAMP1;secretory carrier membrane protein 1,GO:0030136//clathrin-coated vesicle;GO:0016021//integral component of membrane;GO:0042589//zymogen granule membrane;GO:0030672//synaptic vesicle membrane;GO:0055038//recycling endosome membrane;GO:0005802//trans-Golgi network,GO:0006887//exocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0006897//endocytosis;GO:0015031//protein transport,GO:0005515//protein binding;GO:0019904//protein domain specific binding,K08823//Legionellosis;K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
9524,0,1,0,0,5,11,0,0,10,0,0,0,"TECR;trans-2,3-enoyl-CoA reductase",GO:0030176//integral component of endoplasmic reticulum membrane;GO:0005634//nucleus;GO:0005789//endoplasmic reticulum membrane;GO:0005783//endoplasmic reticulum,GO:0044281//small molecule metabolic process;GO:0035338//long-chain fatty-acyl-CoA biosynthetic process;GO:0019432//triglyceride biosynthetic process;GO:0044255//cellular lipid metabolic process;GO:0055114//oxidation-reduction process;GO:0030497//fatty acid elongation;GO:0042761//very long-chain fatty acid biosynthetic process,"GO:0016627//oxidoreductase activity, acting on the CH-CH group of donors",K10258//Biosynthesis of unsaturated fatty acids;Biosynthesis of secondary metabolites;Fatty acid elongation
9525,0,40,22,20,102,0,15,0,23,0,0,0,VPS4B;vacuolar protein sorting 4 homolog B (S. cerevisiae),GO:0005737//cytoplasm;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0005769//early endosome;GO:0010008//endosome membrane;GO:0005774//vacuolar membrane;GO:0005770//late endosome;GO:0005634//nucleus;GO:0031902//late endosome membrane;GO:0005764//lysosome;GO:0005829//cytosol,GO:1902188//positive regulation of viral release from host cell;GO:0016032//viral process;GO:0032510//endosome to lysosome transport via multivesicular body sorting pathway;GO:0051301//cell division;GO:0050792//regulation of viral process;GO:0007032//endosome organization;GO:0006200//ATP catabolic process;GO:0007049//cell cycle;GO:0019058//viral life cycle;GO:0006813//potassium ion transport;GO:0032367//intracellular cholesterol transport;GO:0033993//response to lipid;GO:0016197//endosomal transport;GO:0015031//protein transport;GO:0061024//membrane organization,"GO:0016887//ATPase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0008022//protein C-terminus binding;GO:0042623//ATPase activity, coupled",K12196//Endocytosis
9526,0,69,0,14,29,0,0,11,7,0,0,0,MPDU1;mannose-P-dolichol utilization defect 1,GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0009312//oligosaccharide biosynthetic process;GO:0006457//protein folding;GO:0006810//transport,-,-
9527,97,7,1,23,129,11,1,0,32,0,0,4,GOSR1;golgi SNAP receptor complex member 1,GO:0031201//SNARE complex;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0016020//membrane;GO:0005801//cis-Golgi network,"GO:0042147//retrograde transport, endosome to Golgi;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006891//intra-Golgi vesicle-mediated transport;GO:0015031//protein transport",GO:0005484//SNAP receptor activity,K08495//SNARE interactions in vesicular transport
9528,86,0,0,5,44,12,0,0,0,0,0,0,TMEM59;transmembrane protein 59,GO:0000138//Golgi trans cisterna;GO:0005764//lysosome;GO:0031902//late endosome membrane;GO:0000137//Golgi cis cisterna;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005770//late endosome;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005797//Golgi medial cisterna;GO:0005765//lysosomal membrane,GO:0010955//negative regulation of protein processing;GO:0006914//autophagy;GO:0090285//negative regulation of protein glycosylation in Golgi;GO:0006508//proteolysis;GO:0090005//negative regulation of establishment of protein localization to plasma membrane;GO:0010508//positive regulation of autophagy,GO:0005515//protein binding;GO:0004175//endopeptidase activity,-
9529,0,32,128,74,21,0,6,393,36,0,8,0,BAG5;BCL2-associated athanogene 5,GO:0016234//inclusion body;GO:0016020//membrane;GO:0005739//mitochondrion;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0090083//regulation of inclusion body assembly;GO:1902176//negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway;GO:0070997//neuron death;GO:0061084//negative regulation of protein refolding;GO:0006457//protein folding;GO:0051444//negative regulation of ubiquitin-protein transferase activity;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031397//negative regulation of protein ubiquitination,GO:0051087//chaperone binding;GO:0031625//ubiquitin protein ligase binding;GO:0019901//protein kinase binding;GO:0005515//protein binding,-
953,0,208,128,366,482,0,0,9,191,0,286,1,ENTPD1;ectonucleoside triphosphate diphosphohydrolase 1,GO:0005605//basal lamina;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0030168//platelet activation;GO:0007155//cell adhesion;GO:0009181//purine ribonucleoside diphosphate catabolic process;GO:0006200//ATP catabolic process;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007596//blood coagulation;GO:0008219//cell death,GO:0005524//ATP binding;GO:0017111//nucleoside-triphosphatase activity;GO:0017110//nucleoside-diphosphatase activity;GO:0005515//protein binding,K01510//Pyrimidine metabolism;Purine metabolism;Epstein-Barr virus infection
9530,0,13,0,0,86,0,8,0,45,0,0,0,BAG4;BCL2-associated athanogene 4,GO:0005886//plasma membrane;GO:0005829//cytosol;GO:0005634//nucleus,GO:0071356//cellular response to tumor necrosis factor;GO:0010763//positive regulation of fibroblast migration;GO:0045785//positive regulation of cell adhesion;GO:0051496//positive regulation of stress fiber assembly;GO:0097178//ruffle assembly;GO:0051897//positive regulation of protein kinase B signaling;GO:0030838//positive regulation of actin filament polymerization;GO:0051291//protein heterooligomerization;GO:0035556//intracellular signal transduction;GO:0043066//negative regulation of apoptotic process;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0072659//protein localization to plasma membrane;GO:0071364//cellular response to epidermal growth factor stimulus;GO:0006457//protein folding,GO:0051087//chaperone binding;GO:0044822//poly(A) RNA binding;GO:0005057//receptor signaling protein activity,-
9531,0,0,0,11,1,0,0,0,2,0,0,0,BAG3;BCL2-associated athanogene 3,GO:0005886//plasma membrane;GO:0043005//neuron projection;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0030018//Z disc,GO:0043066//negative regulation of apoptotic process;GO:0071260//cellular response to mechanical stimulus;GO:0050821//protein stabilization;GO:0007420//brain development;GO:0006457//protein folding;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0010664//negative regulation of striated muscle cell apoptotic process;GO:0021510//spinal cord development;GO:0097192//extrinsic apoptotic signaling pathway in absence of ligand,GO:0051087//chaperone binding;GO:0032403//protein complex binding;GO:0005515//protein binding,-
9532,0,0,1,13,1,0,0,0,0,9,0,0,BAG2;BCL2-associated athanogene 2,-,GO:0006457//protein folding;GO:0019538//protein metabolic process,GO:0051087//chaperone binding;GO:0005515//protein binding;GO:0042802//identical protein binding,K09556//Protein processing in endoplasmic reticulum
9533,0,1,0,30,0,0,0,0,7,0,13,0,"POLR1C;polymerase (RNA) I polypeptide C, 30kDa",GO:0005829//cytosol;GO:0005736//DNA-directed RNA polymerase I complex;GO:0005666//DNA-directed RNA polymerase III complex;GO:0005654//nucleoplasm,GO:0006362//transcription elongation from RNA polymerase I promoter;GO:0006386//termination of RNA polymerase III transcription;GO:0006363//termination of RNA polymerase I transcription;GO:0006361//transcription initiation from RNA polymerase I promoter;GO:0006360//transcription from RNA polymerase I promoter;GO:0045087//innate immune response;GO:0006383//transcription from RNA polymerase III promoter;GO:0032481//positive regulation of type I interferon production;GO:0010467//gene expression;GO:0006385//transcription elongation from RNA polymerase III promoter,GO:0001056//RNA polymerase III activity;GO:0003677//DNA binding;GO:0003899//DNA-directed RNA polymerase activity;GO:0046983//protein dimerization activity;GO:0001054//RNA polymerase I activity,K03027//Pyrimidine metabolism;Purine metabolism;RNA polymerase;Epstein-Barr virus infection;Cytosolic DNA-sensing pathway;Metabolic pathways
9534,0,0,0,0,27,0,29,0,12,0,0,0,ZNF254;zinc finger protein 254,GO:0005634//nucleus,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9536,0,0,0,0,0,44,0,46,8,0,0,0,PTGES;prostaglandin E synthase,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005641//nuclear envelope lumen;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0044281//small molecule metabolic process;GO:0007165//signal transduction;GO:0019371//cyclooxygenase pathway;GO:0006693//prostaglandin metabolic process;GO:0002526//acute inflammatory response;GO:0014070//response to organic cyclic compound;GO:0032526//response to retinoic acid;GO:0008285//negative regulation of cell proliferation;GO:0002544//chronic inflammatory response;GO:0051592//response to calcium ion;GO:0034097//response to cytokine;GO:0032496//response to lipopolysaccharide;GO:0001516//prostaglandin biosynthetic process;GO:0019369//arachidonic acid metabolic process,GO:0050220//prostaglandin-E synthase activity;GO:0043295//glutathione binding,K15729//Arachidonic acid metabolism;Metabolic pathways
9537,0,0,1,0,0,24,20,0,19,0,14,0,TP53I11;tumor protein p53 inducible protein 11,GO:0016021//integral component of membrane,GO:0008285//negative regulation of cell proliferation;GO:0006950//response to stress,-,-
9538,80,46,0,60,73,16,16,1,13,0,0,0,EI24;etoposide induced 2.4,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane,GO:0042493//response to drug;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:0006915//apoptotic process;GO:0006914//autophagy;GO:0030308//negative regulation of cell growth;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0050885//neuromuscular process controlling balance,-,K10134//p53 signaling pathway
954,88,0,0,0,0,0,0,0,15,0,0,0,ENTPD2;ectonucleoside triphosphate diphosphohydrolase 2,GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005605//basal lamina;GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0009181//purine ribonucleoside diphosphate catabolic process;GO:0030168//platelet activation,GO:0005524//ATP binding;GO:0017111//nucleoside-triphosphatase activity;GO:0017110//nucleoside-diphosphatase activity,K01509//Purine metabolism
9540,0,0,0,0,31,0,31,66,26,0,14,0,TP53I3;tumor protein p53 inducible protein 3,GO:0070062//extracellular vesicular exosome,GO:0055114//oxidation-reduction process;GO:0006739//NADP metabolic process,GO:0070402//NADPH binding;GO:0048038//quinone binding;GO:0008270//zinc ion binding;GO:0003960//NADPH:quinone reductase activity;GO:0042803//protein homodimerization activity,K10133//p53 signaling pathway
9541,0,0,0,10,71,0,0,0,63,0,0,0,"CIR1;corepressor interacting with RBPJ, 1",GO:0016607//nuclear speck;GO:0000118//histone deacetylase complex;GO:0005815//microtubule organizing center;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter",GO:0003714//transcription corepressor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,K06066//Notch signaling pathway
9542,0,0,0,0,0,0,0,0,15,0,0,0,NRG2;neuregulin 2,GO:0005576//extracellular region;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0048015//phosphatidylinositol-mediated signaling;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007165//signal transduction;GO:0045087//innate immune response;GO:0009790//embryo development;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway,GO:0008083//growth factor activity;GO:0005102//receptor binding,K05456//ErbB signaling pathway
9543,0,29,0,0,0,0,17,33,74,94,0,0,"IGDCC3;immunoglobulin superfamily, DCC subclass, member 3",GO:0005887//integral component of plasma membrane,GO:0050885//neuromuscular process controlling balance,-,K06765//Pathways in cancer;Axon guidance;Colorectal cancer
9545,0,32,29,97,314,11,0,4,40,0,0,0,"RAB3D;RAB3D, member RAS oncogene family",GO:0030133//transport vesicle;GO:0042588//zymogen granule;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005739//mitochondrion,GO:0015031//protein transport;GO:0018125//peptidyl-cysteine methylation;GO:0006184//GTP catabolic process;GO:0007264//small GTPase mediated signal transduction;GO:0006887//exocytosis;GO:0017157//regulation of exocytosis,GO:0003924//GTPase activity;GO:0051020//GTPase binding;GO:0005525//GTP binding,K07884//Pancreatic secretion
9546,0,0,0,0,0,0,35,123,24,0,0,36,"APBA3;amyloid beta (A4) precursor protein-binding, family A, member 3",GO:0048471//perinuclear region of cytoplasm,GO:0043086//negative regulation of catalytic activity;GO:0001701//in utero embryonic development;GO:0010468//regulation of gene expression;GO:0015031//protein transport;GO:0007268//synaptic transmission,GO:0001540//beta-amyloid binding;GO:0019899//enzyme binding;GO:0004857//enzyme inhibitor activity;GO:0005515//protein binding,-
9547,0,0,0,0,0,21,0,1,38,0,0,0,CXCL14;chemokine (C-X-C motif) ligand 14,GO:0005615//extracellular space;GO:0005794//Golgi apparatus,GO:0007267//cell-cell signaling;GO:0006935//chemotaxis;GO:0006955//immune response;GO:0048839//inner ear development;GO:0060326//cell chemotaxis;GO:0007165//signal transduction,GO:0008009//chemokine activity,K10033//Cytokine-cytokine receptor interaction;Chemokine signaling pathway
955,52,0,0,4,13,12,21,173,78,0,0,0,ENTPD6;ectonucleoside triphosphate diphosphohydrolase 6 (putative),GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0009986//cell surface;GO:0005615//extracellular space,GO:0032026//response to magnesium ion;GO:0051592//response to calcium ion;GO:0008152//metabolic process,"GO:0017111//nucleoside-triphosphatase activity;GO:0045134//uridine-diphosphatase activity;GO:0008894//guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity",K01511//Pyrimidine metabolism;Purine metabolism
9550,0,25,1,0,75,11,0,0,0,306,4,0,"ATP6V1G1;ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1",GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016471//vacuolar proton-transporting V-type ATPase complex;GO:0005829//cytosol;GO:0005765//lysosomal membrane,GO:0051701//interaction with host;GO:0015992//proton transport;GO:0033572//transferrin transport;GO:0090382//phagosome maturation;GO:0008286//insulin receptor signaling pathway;GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport,"GO:0016820//hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;GO:0051117//ATPase binding",K02152//Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection;Oxidative phosphorylation;Metabolic pathways;Synaptic vesicle cycle;Rheumatoid arthritis;Collecting duct acid secretion;Phagosome
9551,0,2,1,13,116,0,0,0,14,0,0,0,"ATP5J2;ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2","GO:0016021//integral component of membrane;GO:0070062//extracellular vesicular exosome;GO:0045263//proton-transporting ATP synthase complex, coupling factor F(o);GO:0005743//mitochondrial inner membrane;GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0005634//nucleus",GO:0015992//proton transport;GO:0022904//respiratory electron transport chain;GO:0044281//small molecule metabolic process;GO:0006200//ATP catabolic process;GO:0044237//cellular metabolic process;GO:0042776//mitochondrial ATP synthesis coupled proton transport,GO:0016887//ATPase activity;GO:0022857//transmembrane transporter activity,K02130//Metabolic pathways;Oxidative phosphorylation
9552,0,40,0,12,42,0,1,0,0,0,0,0,SPAG7;sperm associated antigen 7,GO:0005634//nucleus,-,GO:0003676//nucleic acid binding,-
9553,12,27,1,10,66,0,0,0,9,0,0,0,MRPL33;mitochondrial ribosomal protein L33,GO:0005739//mitochondrion;GO:0005840//ribosome,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
9554,0,73,0,38,128,0,26,0,9,0,1,0,SEC22B;SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene),GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0005794//Golgi apparatus;GO:0016021//integral component of membrane;GO:0042470//melanosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment;GO:0005789//endoplasmic reticulum membrane,GO:0006888//ER to Golgi vesicle-mediated transport;GO:0015031//protein transport,GO:0005515//protein binding,K08517//SNARE interactions in vesicular transport;Legionellosis;Phagosome
9555,0,0,0,10,50,0,0,0,14,0,0,0,"H2AFY;H2A histone family, member Y",GO:0000793//condensed chromosome;GO:0070062//extracellular vesicular exosome;GO:0001739//sex chromatin;GO:0000786//nucleosome;GO:0035098//ESC/E(Z) complex;GO:0005730//nucleolus;GO:0001740//Barr body;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0045814//negative regulation of gene expression, epigenetic;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0071901//negative regulation of protein serine/threonine kinase activity;GO:1902750//negative regulation of cell cycle G2/M phase transition;GO:0071169//establishment of protein localization to chromatin;GO:0007549//dosage compensation;GO:1901837//negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter;GO:0061187//regulation of chromatin silencing at rDNA;GO:0016568//chromatin modification;GO:0033128//negative regulation of histone phosphorylation;GO:0006334//nucleosome assembly;GO:0001558//regulation of cell growth",GO:0019901//protein kinase binding;GO:0031490//chromatin DNA binding;GO:0003677//DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0010385//double-stranded methylated DNA binding;GO:0000182//rDNA binding;GO:0046982//protein heterodimerization activity;GO:0005515//protein binding;GO:0030291//protein serine/threonine kinase inhibitor activity,K11251//Systemic lupus erythematosus;Alcoholism
9556,0,0,1,25,34,0,0,0,0,0,0,0,C14orf2;chromosome 14 open reading frame 2,GO:0005753//mitochondrial proton-transporting ATP synthase complex;GO:0016021//integral component of membrane,-,-,-
9557,0,1,0,10,33,17,0,0,37,0,0,0,CHD1L;chromodomain helicase DNA binding protein 1-like,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005730//nucleolus,GO:0006281//DNA repair;GO:0032508//DNA duplex unwinding;GO:0006200//ATP catabolic process;GO:0006338//chromatin remodeling;GO:0006974//cellular response to DNA damage stimulus,GO:0005524//ATP binding;GO:0004003//ATP-dependent DNA helicase activity;GO:0003677//DNA binding;GO:0016887//ATPase activity;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
9559,2,33,0,25,80,27,0,0,51,0,0,0,VPS26A;vacuolar protein sorting 26 homolog A (S. pombe),GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0070062//extracellular vesicular exosome;GO:0005768//endosome;GO:0031982//vesicle,"GO:0015031//protein transport;GO:0042147//retrograde transport, endosome to Golgi",GO:0005515//protein binding;GO:0008565//protein transporter activity,-
956,0,45,1,19,39,0,1,0,0,0,41,342,ENTPD3;ectonucleoside triphosphate diphosphohydrolase 3,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0009134//nucleoside diphosphate catabolic process;GO:0009143//nucleoside triphosphate catabolic process,GO:0005524//ATP binding;GO:0017110//nucleoside-diphosphatase activity;GO:0017111//nucleoside-triphosphatase activity,K01510//Purine metabolism;Epstein-Barr virus infection;Pyrimidine metabolism
9562,0,0,0,0,0,23,24,0,26,0,0,0,MINPP1;multiple inositol-polyphosphate phosphatase 1,GO:0005788//endoplasmic reticulum lumen;GO:0070062//extracellular vesicular exosome;GO:0005783//endoplasmic reticulum,GO:0030282//bone mineralization;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process;GO:0016311//dephosphorylation;GO:0001503//ossification;GO:0006797//polyphosphate metabolic process,GO:0034417//bisphosphoglycerate 3-phosphatase activity;GO:0052826//inositol hexakisphosphate 2-phosphatase activity;GO:0003993//acid phosphatase activity;GO:0008969//phosphohistidine phosphatase activity,K03103//Inositol phosphate metabolism
9563,0,0,0,0,0,12,8,57,18,0,13,0,H6PD;hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase),GO:0005739//mitochondrion;GO:0005788//endoplasmic reticulum lumen,GO:0006098//pentose-phosphate shunt;GO:0097305//response to alcohol,GO:0030246//carbohydrate binding;GO:0047936//glucose 1-dehydrogenase [NAD(P)] activity;GO:0017057//6-phosphogluconolactonase activity;GO:0004345//glucose-6-phosphate dehydrogenase activity;GO:0050661//NADP binding,K13937//Metabolic pathways;Pentose phosphate pathway
9564,0,0,1,1,1,6,35,49,39,0,2,0,BCAR1;breast cancer anti-estrogen resistance 1,GO:0005829//cytosol;GO:0001726//ruffle;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0030027//lamellipodium;GO:0005737//cytoplasm,GO:0007173//epidermal growth factor receptor signaling pathway;GO:0035729//cellular response to hepatocyte growth factor stimulus;GO:0016477//cell migration;GO:0042981//regulation of apoptotic process;GO:0007229//integrin-mediated signaling pathway;GO:0030168//platelet activation;GO:0007596//blood coagulation;GO:0050852//T cell receptor signaling pathway;GO:0007155//cell adhesion;GO:0007015//actin filament organization;GO:0008286//insulin receptor signaling pathway;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0001558//regulation of cell growth;GO:0051301//cell division;GO:0050853//B cell receptor signaling pathway;GO:0060326//cell chemotaxis;GO:0048012//hepatocyte growth factor receptor signaling pathway;GO:0010595//positive regulation of endothelial cell migration;GO:0048008//platelet-derived growth factor receptor signaling pathway;GO:0050851//antigen receptor-mediated signaling pathway;GO:0048010//vascular endothelial growth factor receptor signaling pathway;GO:0008283//cell proliferation;GO:0007186//G-protein coupled receptor signaling pathway;GO:0030335//positive regulation of cell migration,GO:0019901//protein kinase binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0004871//signal transducer activity,K05726//Focal adhesion;Leukocyte transendothelial migration;Regulation of actin cytoskeleton;Bacterial invasion of epithelial cells;Chemokine signaling pathway
9567,0,39,0,0,11,2,18,0,27,4,1,56,GTPBP1;GTP binding protein 1,GO:0016020//membrane;GO:0005829//cytosol;GO:0000177//cytoplasmic exosome (RNase complex),GO:0061014//positive regulation of mRNA catabolic process;GO:0007165//signal transduction;GO:0006184//GTP catabolic process;GO:0006955//immune response,GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0044822//poly(A) RNA binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K14416//mRNA surveillance pathway;Legionellosis
9568,93,0,0,4,10,14,26,0,64,0,14,0,"GABBR2;gamma-aminobutyric acid (GABA) B receptor, 2",GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0043005//neuron projection;GO:0005737//cytoplasm;GO:0038039//G-protein coupled receptor heterodimeric complex;GO:0005887//integral component of plasma membrane,GO:0007194//negative regulation of adenylate cyclase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0007268//synaptic transmission;GO:0007214//gamma-aminobutyric acid signaling pathway,GO:0005515//protein binding;GO:0004965//G-protein coupled GABA receptor activity,K04615//Morphine addiction;GABAergic synapse;Neuroactive ligand-receptor interaction
95681,0,0,0,0,0,12,34,0,146,0,11,319,CEP41;centrosomal protein 41kDa,GO:0005813//centrosome;GO:0072372//primary cilium;GO:0036064//ciliary basal body;GO:0016020//membrane;GO:0005814//centriole;GO:0005829//cytosol,GO:0018095//protein polyglutamylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0042384//cilium assembly;GO:0015031//protein transport,GO:0005515//protein binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K01875//Biotin metabolism;Arginine and proline metabolism;Metabolic pathways;Aminoacyl-tRNA biosynthesis;K11447//Transcriptional misregulation in cancer
9569,0,0,0,13,12,0,24,0,42,105,17,138,GTF2IRD1;GTF2I repeat domain containing 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0007275//multicellular organismal development;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0006366//transcription from RNA polymerase II promoter",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,K03121//Basal transcription factors;Herpes simplex infection
957,0,24,0,20,36,0,0,0,41,0,0,0,ENTPD5;ectonucleoside triphosphate diphosphohydrolase 5,GO:0005783//endoplasmic reticulum;GO:0070062//extracellular vesicular exosome,GO:0006487//protein N-linked glycosylation;GO:0045821//positive regulation of glycolytic process;GO:0046034//ATP metabolic process;GO:0008283//cell proliferation;GO:0014066//regulation of phosphatidylinositol 3-kinase signaling;GO:0051084//'de novo' posttranslational protein folding;GO:0016049//cell growth,GO:0004382//guanosine-diphosphatase activity;GO:0045134//uridine-diphosphatase activity,K01511//Purine metabolism;Pyrimidine metabolism
9570,0,51,0,29,142,8,27,52,44,0,11,0,GOSR2;golgi SNAP receptor complex member 2,GO:0005795//Golgi stack;GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0015031//protein transport;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0044267//cellular protein metabolic process;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0061025//membrane fusion,GO:0005215//transporter activity,K08496//SNARE interactions in vesicular transport
9572,2,291,2,71,167,0,7,1650,73,437,449,1,"NR1D1;nuclear receptor subfamily 1, group D, member 1",GO:0005737//cytoplasm;GO:0043197//dendritic spine;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0030425//dendrite,"GO:0071222//cellular response to lipopolysaccharide;GO:2000188//regulation of cholesterol homeostasis;GO:0030154//cell differentiation;GO:0030522//intracellular receptor signaling pathway;GO:2000189//positive regulation of cholesterol homeostasis;GO:0010871//negative regulation of receptor biosynthetic process;GO:0061469//regulation of type B pancreatic cell proliferation;GO:0034144//negative regulation of toll-like receptor 4 signaling pathway;GO:0060086//circadian temperature homeostasis;GO:0042752//regulation of circadian rhythm;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0061178//regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0070859//positive regulation of bile acid biosynthetic process;GO:0005978//glycogen biosynthetic process;GO:0045893//positive regulation of transcription, DNA-templated;GO:0035947//regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter;GO:0010498//proteasomal protein catabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0045598//regulation of fat cell differentiation;GO:0019216//regulation of lipid metabolic process;GO:0044321//response to leptin;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032922//circadian regulation of gene expression",GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0020037//heme binding;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003714//transcription corepressor activity;GO:0001046//core promoter sequence-specific DNA binding;GO:0044212//transcription regulatory region DNA binding;GO:0001222//transcription corepressor binding;GO:0005515//protein binding;GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,K03728//Circadian rhythm - mammal
9575,0,38,1,47,105,0,86,0,46,1,8,0,CLOCK;clock circadian regulator,GO:0005634//nucleus;GO:0005667//transcription factor complex;GO:0005730//nucleolus;GO:0005694//chromosome;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0033391//chromatoid body,"GO:0042634//regulation of hair cycle;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0009648//photoperiodism;GO:0016573//histone acetylation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0007623//circadian rhythm;GO:0007283//spermatogenesis;GO:0045892//negative regulation of transcription, DNA-templated;GO:0006366//transcription from RNA polymerase II promoter;GO:2000074//regulation of type B pancreatic cell development;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006355//regulation of transcription, DNA-templated;GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0071479//cellular response to ionizing radiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0000077//DNA damage checkpoint;GO:2000323//negative regulation of glucocorticoid receptor signaling pathway;GO:0051775//response to redox state;GO:0006325//chromatin organization;GO:0050796//regulation of insulin secretion;GO:0032922//circadian regulation of gene expression",GO:0000982//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0070888//E-box binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046983//protein dimerization activity;GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0001047//core promoter binding;GO:0003677//DNA binding;GO:0004871//signal transducer activity;GO:0004402//histone acetyltransferase activity;GO:0043565//sequence-specific DNA binding;GO:0031490//chromatin DNA binding,K02223//Circadian rhythm - mammal;Circadian rhythm - fly;Herpes simplex infection;Dopaminergic synapse
9576,0,0,0,0,14,0,0,0,12,35,0,0,SPAG6;sperm associated antigen 6,GO:0031514//motile cilium;GO:0005930//axoneme;GO:0005634//nucleus;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule,GO:0030030//cell projection organization;GO:0007286//spermatid development,-,K15043//Influenza A;K15042//Influenza A
9577,0,37,0,0,31,8,0,0,0,0,0,0,BRE;brain and reproductive organ-expressed (TNFRSF1A modulator),GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0000152//nuclear ubiquitin ligase complex;GO:0070531//BRCA1-A complex;GO:0070552//BRISC complex,GO:0006915//apoptotic process;GO:0045739//positive regulation of DNA repair;GO:0007165//signal transduction;GO:0006302//double-strand break repair;GO:0016568//chromatin modification;GO:0010212//response to ionizing radiation;GO:0031572//G2 DNA damage checkpoint;GO:0006974//cellular response to DNA damage stimulus,GO:0000268//peroxisome targeting sequence binding;GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0031593//polyubiquitin binding,-
9578,8,78,0,6,78,27,46,24,55,148,10,300,CDC42BPB;CDC42 binding protein kinase beta (DMPK-like),GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0031252//cell leading edge;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0042641//actomyosin;GO:0005911//cell-cell junction,GO:0016477//cell migration;GO:0031032//actomyosin structure organization;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity;GO:0035556//intracellular signal transduction;GO:0007010//cytoskeleton organization;GO:0031532//actin cytoskeleton reorganization;GO:0007163//establishment or maintenance of cell polarity;GO:0006468//protein phosphorylation,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0005083//small GTPase regulator activity;GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0017048//Rho GTPase binding,-
9580,0,13,0,0,7,0,0,61,24,0,0,0,SOX13;SRY (sex determining region Y)-box 13,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0045586//regulation of gamma-delta T cell differentiation;GO:0006351//transcription, DNA-templated;GO:0009653//anatomical structure morphogenesis",GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
9581,66,7,61,109,202,15,2,21,53,0,7,0,PREPL;prolyl endopeptidase-like,GO:0005856//cytoskeleton;GO:0005794//Golgi apparatus;GO:0005829//cytosol,GO:0006508//proteolysis,GO:0004252//serine-type endopeptidase activity;GO:0070008//serine-type exopeptidase activity,K14210//Protein digestion and absorption
9582,0,1,0,6,0,0,0,0,0,0,0,0,"APOBEC3B;apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B",GO:0005634//nucleus,GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0010529//negative regulation of transposition;GO:0008152//metabolic process,GO:0044822//poly(A) RNA binding;GO:0047844//deoxycytidine deaminase activity;GO:0008270//zinc ion binding,K01500//Microbial metabolism in diverse environments;Atrazine degradation
9583,0,0,8,0,25,14,0,0,36,90,0,0,ENTPD4;ectonucleoside triphosphate diphosphohydrolase 4,GO:0000421//autophagic vacuole membrane;GO:0031410//cytoplasmic vesicle;GO:0030173//integral component of Golgi membrane;GO:0043231//intracellular membrane-bounded organelle,GO:0006256//UDP catabolic process,GO:0045134//uridine-diphosphatase activity,K12305//Lysosome;Purine metabolism;Pyrimidine metabolism
9584,0,41,20,29,75,0,0,0,13,0,9,0,RBM39;RNA binding motif protein 39,GO:0005654//nucleoplasm;GO:0005815//microtubule organizing center;GO:0015630//microtubule cytoskeleton;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0006396//RNA processing;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0006355//regulation of transcription, DNA-templated",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,-
9585,79,3,0,0,3,6,0,26,103,66,3,1,KIF20B;kinesin family member 20B,GO:0005730//nucleolus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005874//microtubule;GO:0005654//nucleoplasm,GO:2001222//regulation of neuron migration;GO:0007018//microtubule-based movement;GO:0001843//neural tube closure;GO:0007067//mitotic nuclear division;GO:0007050//cell cycle arrest;GO:0070201//regulation of establishment of protein localization;GO:0007088//regulation of mitosis;GO:0006200//ATP catabolic process;GO:2000114//regulation of establishment of cell polarity,GO:0005524//ATP binding;GO:0050699//WW domain binding;GO:0016887//ATPase activity;GO:0003777//microtubule motor activity;GO:0008017//microtubule binding,-
9586,0,0,0,0,5,0,0,122,15,70,0,1,CREB5;cAMP responsive element binding protein 5,GO:0070062//extracellular vesicular exosome;GO:0005634//nucleus,"GO:0060612//adipose tissue development;GO:0006366//transcription from RNA polymerase II promoter;GO:0045444//fat cell differentiation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0043565//sequence-specific DNA binding;GO:0001077//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,K09047//Prostate cancer;Alcoholism;Cholinergic synapse;Huntington's disease;Cocaine addiction;Dopaminergic synapse;Vasopressin-regulated water reabsorption;Amphetamine addiction
9587,0,0,0,0,1,0,0,0,0,0,3,0,MAD2L1BP;MAD2L1 binding protein,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle,GO:0007093//mitotic cell cycle checkpoint;GO:0007096//regulation of exit from mitosis,GO:0005515//protein binding,K01875//Aminoacyl-tRNA biosynthesis;Metabolic pathways;Biotin metabolism;Arginine and proline metabolism;K12756//Leukocyte transendothelial migration;Focal adhesion;Regulation of actin cytoskeleton;Tight junction;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
9588,0,218,5,96,395,0,0,53,4,0,6,0,PRDX6;peroxiredoxin 6,GO:0070062//extracellular vesicular exosome;GO:0016020//membrane;GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005615//extracellular space;GO:0005737//cytoplasm;GO:0005764//lysosome,GO:0055114//oxidation-reduction process;GO:0042744//hydrogen peroxide catabolic process;GO:0009395//phospholipid catabolic process;GO:0006979//response to oxidative stress,GO:0051920//peroxiredoxin activity;GO:0016209//antioxidant activity;GO:0005515//protein binding;GO:0004623//phospholipase A2 activity;GO:0004602//glutathione peroxidase activity,K11188//Phenylpropanoid biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Phenylalanine metabolism
9589,72,249,141,286,487,21,52,510,144,2,485,315,WTAP;Wilms tumor 1 associated protein,GO:0036396//MIS complex;GO:0031965//nuclear membrane;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0005730//nucleolus,"GO:0080009//mRNA methylation;GO:0007049//cell cycle;GO:0008380//RNA splicing;GO:0006397//mRNA processing;GO:0000381//regulation of alternative mRNA splicing, via spliceosome",-,-
959,0,0,0,0,0,0,25,0,0,0,0,32,CD40LG;CD40 ligand,GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016021//integral component of membrane,GO:0051023//regulation of immunoglobulin secretion;GO:2000353//positive regulation of endothelial cell apoptotic process;GO:0045190//isotype switching;GO:0030168//platelet activation;GO:0007159//leukocyte cell-cell adhesion;GO:0030183//B cell differentiation;GO:0042100//B cell proliferation;GO:0006954//inflammatory response;GO:0050776//regulation of immune response;GO:0043066//negative regulation of apoptotic process;GO:0048305//immunoglobulin secretion;GO:0032735//positive regulation of interleukin-12 production,GO:0005174//CD40 receptor binding;GO:0005125//cytokine activity;GO:0005164//tumor necrosis factor receptor binding,K03161//Asthma;Viral myocarditis;Toxoplasmosis;Systemic lupus erythematosus;T cell receptor signaling pathway;Cell adhesion molecules (CAMs);Cytokine-cytokine receptor interaction;Allograft rejection;Intestinal immune network for IgA production;Malaria;Primary immunodeficiency;Autoimmune thyroid disease;NF-kappa B signaling pathway
9590,55,19,1,61,454,0,16,0,40,0,0,89,AKAP12;A kinase (PRKA) anchor protein 12,GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005938//cell cortex;GO:0005925//focal adhesion,GO:0090036//regulation of protein kinase C signaling;GO:0010739//positive regulation of protein kinase A signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006605//protein targeting;GO:0030819//positive regulation of cAMP biosynthetic process,GO:0051018//protein kinase A binding;GO:0008179//adenylate cyclase binding;GO:0005515//protein binding,K00907//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Focal adhesion;Calcium signaling pathway;Gastric acid secretion
9592,0,0,0,0,0,0,0,0,1,0,21,0,IER2;immediate early response 2,GO:0005737//cytoplasm,-,-,-
960,0,0,0,6,62,3,0,65,30,0,0,0,CD44;CD44 molecule (Indian blood group),GO:0009986//cell surface;GO:0005794//Golgi apparatus;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0005887//integral component of plasma membrane,"GO:0043066//negative regulation of apoptotic process;GO:0016337//single organismal cell-cell adhesion;GO:0010628//positive regulation of gene expression;GO:0070487//monocyte aggregation;GO:0034116//positive regulation of heterotypic cell-cell adhesion;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0051216//cartilage development;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0044281//small molecule metabolic process;GO:0060442//branching involved in prostate gland morphogenesis;GO:0030198//extracellular matrix organization;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0002246//wound healing involved in inflammatory response;GO:0019221//cytokine-mediated signaling pathway;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0044344//cellular response to fibroblast growth factor stimulus;GO:0060333//interferon-gamma-mediated signaling pathway;GO:0007160//cell-matrix adhesion;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0007596//blood coagulation;GO:0030214//hyaluronan catabolic process;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0030203//glycosaminoglycan metabolic process;GO:0050900//leukocyte migration;GO:0001658//branching involved in ureteric bud morphogenesis;GO:1900625//positive regulation of monocyte aggregation;GO:0030212//hyaluronan metabolic process;GO:0016055//Wnt signaling pathway;GO:0022617//extracellular matrix disassembly;GO:0005975//carbohydrate metabolic process",GO:0004415//hyalurononglucosaminidase activity;GO:0005518//collagen binding;GO:0005540//hyaluronic acid binding;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity,K06256//ECM-receptor interaction;Hematopoietic cell lineage;Epstein-Barr virus infection;Shigellosis
9600,0,0,0,0,8,38,9,0,60,0,1,0,"PITPNM1;phosphatidylinositol transfer protein, membrane-associated 1",GO:0030496//midbody;GO:0005811//lipid particle;GO:0032580//Golgi cisterna membrane;GO:0032154//cleavage furrow;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007420//brain development;GO:0015914//phospholipid transport;GO:0015031//protein transport;GO:0007602//phototransduction;GO:0006629//lipid metabolic process,GO:0046872//metal ion binding;GO:0008526//phosphatidylinositol transporter activity,K01106//Phosphatidylinositol signaling system;Metabolic pathways;Insulin signaling pathway;Inositol phosphate metabolism
9601,0,28,2,0,15,0,0,1,12,144,0,0,"PDIA4;protein disulfide isomerase family A, member 4",GO:0005788//endoplasmic reticulum lumen;GO:0009986//cell surface;GO:0005783//endoplasmic reticulum;GO:0042470//melanosome,GO:0009306//protein secretion;GO:0061077//chaperone-mediated protein folding;GO:0045454//cell redox homeostasis;GO:0034976//response to endoplasmic reticulum stress;GO:0006457//protein folding,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003756//protein disulfide isomerase activity,K09582//Vibrio cholerae infection;Protein processing in endoplasmic reticulum
9603,0,0,0,11,0,4,6,0,25,0,0,0,"NFE2L3;nuclear factor, erythroid 2-like 3",GO:0005634//nucleus,GO:0006366//transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0000978//RNA polymerase II core promoter proximal region sequence-specific DNA binding;GO:0003713//transcription coactivator activity;GO:0001078//RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription;GO:0003700//sequence-specific DNA binding transcription factor activity,-
9604,0,70,1,60,107,25,0,41,32,80,4,0,RNF14;ring finger protein 14,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0016567//protein ubiquitination;GO:0030521//androgen receptor signaling pathway;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0060765//regulation of androgen receptor signaling pathway;GO:0007165//signal transduction;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0032355//response to estradiol",GO:0003713//transcription coactivator activity;GO:0019787//small conjugating protein ligase activity;GO:0050681//androgen receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding,-
9605,0,0,0,5,30,12,0,0,31,0,56,0,VPS9D1;VPS9 domain containing 1,-,GO:0043547//positive regulation of GTPase activity;GO:0015986//ATP synthesis coupled proton transport,GO:0005215//transporter activity;GO:0005096//GTPase activator activity,-
9607,0,0,0,0,9,22,0,0,0,158,0,0,CARTPT;CART prepropeptide,GO:0005615//extracellular space;GO:0030141//secretory granule,GO:0007267//cell-cell signaling;GO:0070093//negative regulation of glucagon secretion;GO:0045777//positive regulation of blood pressure;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032922//circadian regulation of gene expression;GO:0007218//neuropeptide signaling pathway;GO:0050796//regulation of insulin secretion;GO:0008343//adult feeding behavior;GO:0000186//activation of MAPKK activity;GO:0032099//negative regulation of appetite;GO:0070253//somatostatin secretion;GO:0007165//signal transduction;GO:0009267//cellular response to starvation;GO:0045779//negative regulation of bone resorption;GO:0032812//positive regulation of epinephrine secretion;GO:0001678//cellular glucose homeostasis;GO:0051971//positive regulation of transmission of nerve impulse;GO:0007268//synaptic transmission;GO:0045671//negative regulation of osteoclast differentiation,GO:0005515//protein binding,-
9609,0,0,0,0,1,1,0,0,18,0,12,0,"RAB36;RAB36, member RAS oncogene family",GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus,GO:0007264//small GTPase mediated signal transduction;GO:0015031//protein transport,GO:0005525//GTP binding,-
961,4,0,0,13,0,14,0,0,2,0,0,0,CD47;CD47 molecule,GO:0005887//integral component of plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane,GO:0007596//blood coagulation;GO:0050729//positive regulation of inflammatory response;GO:0022409//positive regulation of cell-cell adhesion;GO:0007155//cell adhesion;GO:0030198//extracellular matrix organization;GO:0008228//opsonization;GO:0009617//response to bacterium;GO:0050870//positive regulation of T cell activation;GO:0008284//positive regulation of cell proliferation;GO:0050766//positive regulation of phagocytosis;GO:0007229//integrin-mediated signaling pathway;GO:0050900//leukocyte migration,GO:0070053//thrombospondin receptor activity;GO:0005515//protein binding,K06266//ECM-receptor interaction
9610,0,0,0,0,0,7,12,0,38,0,1,0,RIN1;Ras and Rab interactor 1,GO:0030425//dendrite;GO:0005886//plasma membrane;GO:0005856//cytoskeleton;GO:0043025//neuronal cell body;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0031914//negative regulation of synaptic plasticity;GO:0007613//memory;GO:0043547//positive regulation of GTPase activity;GO:0008306//associative learning;GO:0006897//endocytosis,GO:0017016//Ras GTPase binding;GO:0005096//GTPase activator activity;GO:0005515//protein binding,-
9611,87,1,2,25,270,53,28,70,115,95,7,0,NCOR1;nuclear receptor corepressor 1,GO:0017053//transcriptional repressor complex;GO:0000118//histone deacetylase complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0016580//Sin3 complex;GO:0005654//nucleoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus;GO:0005876//spindle microtubule;GO:0005667//transcription factor complex,"GO:0042632//cholesterol homeostasis;GO:0006366//transcription from RNA polymerase II promoter;GO:0046329//negative regulation of JNK cascade;GO:0021794//thalamus development;GO:0072368//regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter;GO:0060318//definitive erythrocyte differentiation;GO:0051225//spindle assembly;GO:2000191//regulation of fatty acid transport;GO:0040014//regulation of multicellular organism growth;GO:0031065//positive regulation of histone deacetylation;GO:0014067//negative regulation of phosphatidylinositol 3-kinase signaling;GO:0007219//Notch signaling pathway;GO:0016568//chromatin modification;GO:0072362//regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter;GO:0002361//CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation;GO:0032922//circadian regulation of gene expression;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010467//gene expression;GO:0044255//cellular lipid metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0044281//small molecule metabolic process",GO:0043565//sequence-specific DNA binding;GO:0042826//histone deacetylase binding;GO:0003714//transcription corepressor activity;GO:0046966//thyroid hormone receptor binding;GO:0003682//chromatin binding;GO:0035257//nuclear hormone receptor binding;GO:0035033//histone deacetylase regulator activity;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0001102//RNA polymerase II activating transcription factor binding;GO:0046965//retinoid X receptor binding;GO:0044212//transcription regulatory region DNA binding,K04650//Transcriptional misregulation in cancer
9612,78,28,1,14,49,13,35,55,73,0,21,2,NCOR2;nuclear receptor corepressor 2,GO:0016363//nuclear matrix;GO:0016604//nuclear body;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0016020//membrane;GO:0017053//transcriptional repressor complex;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0072365//regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0044281//small molecule metabolic process;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0007219//Notch signaling pathway;GO:0044255//cellular lipid metabolic process",GO:0047485//protein N-terminus binding;GO:0005112//Notch binding;GO:0003714//transcription corepressor activity;GO:0003682//chromatin binding;GO:0042826//histone deacetylase binding;GO:0005515//protein binding;GO:0003677//DNA binding,K06065//Notch signaling pathway;Epstein-Barr virus infection
9615,0,0,0,0,0,12,0,0,84,0,0,0,GDA;guanine deaminase,GO:0070062//extracellular vesicular exosome;GO:0005622//intracellular;GO:0005829//cytosol,GO:0006139//nucleobase-containing compound metabolic process;GO:0007399//nervous system development;GO:0044281//small molecule metabolic process;GO:0006147//guanine catabolic process;GO:0006195//purine nucleotide catabolic process;GO:0006144//purine nucleobase metabolic process,GO:0008892//guanine deaminase activity;GO:0008270//zinc ion binding,K01487//Metabolic pathways;Pyrimidine metabolism;Arginine and proline metabolism;Purine metabolism
9616,0,0,0,24,32,0,16,0,6,0,0,0,RNF7;ring finger protein 7,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0005730//nucleolus,GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0051775//response to redox state;GO:0016567//protein ubiquitination;GO:0045116//protein neddylation;GO:0043066//negative regulation of apoptotic process,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0019788//NEDD8 ligase activity;GO:0005507//copper ion binding,K10611//Ubiquitin mediated proteolysis
9617,0,0,0,0,8,6,0,0,31,0,0,0,MTRF1;mitochondrial translational release factor 1,GO:0005739//mitochondrion,GO:0006415//translational termination;GO:0006449//regulation of translational termination,"GO:0016149//translation release factor activity, codon specific;GO:0003747//translation release factor activity",-
9618,0,0,0,11,0,8,0,0,0,0,11,0,TRAF4;TNF receptor-associated factor 4,GO:0005923//tight junction;GO:0005886//plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005856//cytoskeleton;GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006915//apoptotic process;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0016567//protein ubiquitination;GO:0046330//positive regulation of JNK cascade;GO:0042981//regulation of apoptotic process;GO:0007585//respiratory gaseous exchange;GO:0090073//positive regulation of protein homodimerization activity;GO:0045860//positive regulation of protein kinase activity;GO:0030323//respiratory tube development;GO:0007165//signal transduction,GO:0008270//zinc ion binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0005164//tumor necrosis factor receptor binding;GO:0031996//thioesterase binding;GO:0050699//WW domain binding;GO:0003677//DNA binding;GO:0019901//protein kinase binding;GO:0031625//ubiquitin protein ligase binding,K09848//Small cell lung cancer;Pathways in cancer
9619,0,0,0,0,1,0,0,0,40,0,16,0,"ABCG1;ATP-binding cassette, sub-family G (WHITE), member 1",GO:0005739//mitochondrion;GO:0055037//recycling endosome;GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0000139//Golgi membrane;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome,"GO:0034374//low-density lipoprotein particle remodeling;GO:0055085//transmembrane transport;GO:1901998//toxin transport;GO:0008203//cholesterol metabolic process;GO:0010872//regulation of cholesterol esterification;GO:0033993//response to lipid;GO:0043691//reverse cholesterol transport;GO:0033344//cholesterol efflux;GO:0006355//regulation of transcription, DNA-templated;GO:0044281//small molecule metabolic process;GO:0055099//response to high density lipoprotein particle;GO:0010033//response to organic substance;GO:0033700//phospholipid efflux;GO:0042987//amyloid precursor protein catabolic process;GO:0042632//cholesterol homeostasis;GO:0010745//negative regulation of macrophage derived foam cell differentiation;GO:0032367//intracellular cholesterol transport;GO:0055091//phospholipid homeostasis;GO:0034375//high-density lipoprotein particle remodeling;GO:0010887//negative regulation of cholesterol storage;GO:0045542//positive regulation of cholesterol biosynthetic process;GO:0006200//ATP catabolic process;GO:0009720//detection of hormone stimulus;GO:0010875//positive regulation of cholesterol efflux;GO:0042157//lipoprotein metabolic process;GO:0034436//glycoprotein transport",GO:0019534//toxin transporter activity;GO:0005524//ATP binding;GO:0046983//protein dimerization activity;GO:0017127//cholesterol transporter activity;GO:0005548//phospholipid transporter activity;GO:0015485//cholesterol binding;GO:0043531//ADP binding;GO:0034437//glycoprotein transporter activity;GO:0005543//phospholipid binding;GO:0034041//sterol-transporting ATPase activity;GO:0005515//protein binding;GO:0042803//protein homodimerization activity;GO:0046982//protein heterodimerization activity,K05679//ABC transporters
962,0,0,0,0,0,0,0,0,11,0,0,46,CD48;CD48 molecule,GO:0043234//protein complex;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0045121//membrane raft;GO:0016020//membrane;GO:0005887//integral component of plasma membrane;GO:0046658//anchored component of plasma membrane,GO:0007165//signal transduction;GO:0050900//leukocyte migration;GO:0042110//T cell activation;GO:0045576//mast cell activation;GO:0007596//blood coagulation;GO:0006952//defense response,GO:0003823//antigen binding;GO:0005515//protein binding;GO:0004872//receptor activity,K06479//Natural killer cell mediated cytotoxicity
9620,173,12,0,0,0,31,32,191,96,0,36,315,"CELSR1;cadherin, EGF LAG seven-pass G-type receptor 1",GO:0005634//nucleus;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0016021//integral component of membrane,GO:0007417//central nervous system development;GO:0007186//G-protein coupled receptor signaling pathway;GO:0032956//regulation of actin cytoskeleton organization;GO:0007218//neuropeptide signaling pathway;GO:0042060//wound healing;GO:0001736//establishment of planar polarity;GO:0060490//lateral sprouting involved in lung morphogenesis;GO:0048105//establishment of body hair planar orientation;GO:0090251//protein localization involved in establishment of planar polarity;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0042472//inner ear morphogenesis;GO:0001942//hair follicle development;GO:0007626//locomotory behavior;GO:0001764//neuron migration;GO:0060488//orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis;GO:0007266//Rho protein signal transduction;GO:0042249//establishment of planar polarity of embryonic epithelium;GO:0001843//neural tube closure;GO:0045176//apical protein localization;GO:0060489//planar dichotomous subdivision of terminal units involved in lung branching morphogenesis;GO:0090179//planar cell polarity pathway involved in neural tube closure;GO:0009952//anterior/posterior pattern specification,GO:0004930//G-protein coupled receptor activity;GO:0046983//protein dimerization activity;GO:0004888//transmembrane signaling receptor activity;GO:0005509//calcium ion binding,-
9622,0,52,47,64,57,0,0,1,29,0,1,0,KLK4;kallikrein-related peptidase 4,GO:0005576//extracellular region,GO:0097186//amelogenesis;GO:0022617//extracellular matrix disassembly;GO:0030163//protein catabolic process;GO:0006508//proteolysis,GO:0008236//serine-type peptidase activity;GO:0004252//serine-type endopeptidase activity;GO:0046872//metal ion binding,-
9625,0,0,0,0,11,0,5,58,30,0,14,0,AATK;apoptosis-associated tyrosine kinase,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0048471//perinuclear region of cytoplasm;GO:0044295//axonal growth cone;GO:0055037//recycling endosome,GO:0032482//Rab protein signal transduction;GO:0030517//negative regulation of axon extension;GO:0051402//neuron apoptotic process;GO:0038083//peptidyl-tyrosine autophosphorylation;GO:0007420//brain development,GO:0004713//protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity,-
9626,0,0,0,0,0,0,0,0,8,0,0,0,GUCA1C;guanylate cyclase activator 1C,GO:0097381//photoreceptor disc membrane,"GO:0016056//rhodopsin mediated signaling pathway;GO:0022400//regulation of rhodopsin mediated signaling pathway;GO:0031284//positive regulation of guanylate cyclase activity;GO:0007603//phototransduction, visible light;GO:0007601//visual perception;GO:0007165//signal transduction",GO:0005509//calcium ion binding;GO:0008048//calcium sensitive guanylate cyclase activator activity,K08328//Olfactory transduction;Phototransduction
9627,0,0,0,0,0,18,0,0,17,0,0,0,"SNCAIP;synuclein, alpha interacting protein",GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0008021//synaptic vesicle;GO:0042734//presynaptic membrane,GO:0090083//regulation of inclusion body assembly;GO:0008219//cell death;GO:0042417//dopamine metabolic process;GO:0046928//regulation of neurotransmitter secretion,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0042802//identical protein binding,K04558//Parkinson's disease
9628,6,0,0,0,0,52,0,0,28,0,0,0,RGS6;regulator of G-protein signaling 6,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0005834//heterotrimeric G-protein complex,GO:0035556//intracellular signal transduction;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0045666//positive regulation of neuron differentiation;GO:0043547//positive regulation of GTPase activity;GO:0007186//G-protein coupled receptor signaling pathway;GO:0008277//regulation of G-protein coupled receptor protein signaling pathway,GO:0005096//GTPase activator activity;GO:0004871//signal transducer activity;GO:0005515//protein binding,K13765//Phototransduction;Cocaine addiction
9629,0,0,0,0,0,16,0,0,23,0,24,0,"CLCA3P;chloride channel accessory 3, pseudogene",GO:0034707//chloride channel complex;GO:0005615//extracellular space,GO:0070588//calcium ion transmembrane transport;GO:0034765//regulation of ion transmembrane transport;GO:0006810//transport;GO:1902476//chloride transmembrane transport,GO:0005244//voltage-gated ion channel activity;GO:0005254//chloride channel activity;GO:0005215//transporter activity;GO:0005262//calcium channel activity,K05030//Pancreatic secretion;Olfactory transduction
963,0,0,0,0,0,0,0,0,46,0,0,0,CD53;CD53 molecule,GO:0009986//cell surface;GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005911//cell-cell junction;GO:0001772//immunological synapse,GO:1901741//positive regulation of myoblast fusion;GO:0007165//signal transduction,GO:0005515//protein binding,-
9630,0,0,0,0,0,13,0,0,0,42,22,0,"GNA14;guanine nucleotide binding protein (G protein), alpha 14",GO:0005834//heterotrimeric G-protein complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0007188//adenylate cyclase-modulating G-protein coupled receptor signaling pathway;GO:0030168//platelet activation;GO:0006184//GTP catabolic process;GO:0060158//phospholipase C-activating dopamine receptor signaling pathway;GO:0007596//blood coagulation,GO:0046872//metal ion binding;GO:0004871//signal transducer activity;GO:0001664//G-protein coupled receptor binding;GO:0003924//GTPase activity;GO:0005525//GTP binding;GO:0031683//G-protein beta/gamma-subunit complex binding,K04636//Amoebiasis;Calcium signaling pathway;Chagas disease (American trypanosomiasis)
9631,74,0,0,16,18,0,8,40,32,0,15,0,NUP155;nucleoporin 155kDa,GO:0016020//membrane;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0005643//nuclear pore,GO:0010827//regulation of glucose transport;GO:0005975//carbohydrate metabolic process;GO:0006406//mRNA export from nucleus;GO:0007077//mitotic nuclear envelope disassembly;GO:0016032//viral process;GO:0006606//protein import into nucleus;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0006998//nuclear envelope organization;GO:0019221//cytokine-mediated signaling pathway;GO:0086014//atrial cardiac muscle cell action potential;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport,GO:0005215//transporter activity;GO:0017056//structural constituent of nuclear pore,K14312//RNA transport
9632,123,50,2,51,263,12,27,155,14,0,17,0,SEC24C;SEC24 family member C,GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0030127//COPII vesicle coat,GO:0048208//COPII vesicle coating;GO:0044281//small molecule metabolic process;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0006886//intracellular protein transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0043687//post-translational protein modification;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0005515//protein binding;GO:0008270//zinc ion binding,K14007//Protein processing in endoplasmic reticulum
9633,0,32,1,0,0,0,52,0,3,0,0,0,"MTL5;metallothionein-like 5, testis-specific (tesmin)",GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0010038//response to metal ion;GO:0006875//cellular metal ion homeostasis;GO:0007283//spermatogenesis,GO:0046872//metal ion binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K11447//Transcriptional misregulation in cancer
9635,115,0,0,0,0,54,0,0,20,0,1,0,CLCA2;chloride channel accessory 2,GO:0030054//cell junction;GO:0005576//extracellular region;GO:0009925//basal plasma membrane;GO:0005887//integral component of plasma membrane,GO:0007155//cell adhesion;GO:1902476//chloride transmembrane transport;GO:0006810//transport,GO:0005254//chloride channel activity;GO:0015276//ligand-gated ion channel activity,K05028//Pancreatic secretion;Olfactory transduction
9636,0,0,0,8,0,1,0,0,0,0,0,0,ISG15;ISG15 ubiquitin-like modifier,GO:0005829//cytosol;GO:0005576//extracellular region,GO:0045648//positive regulation of erythrocyte differentiation;GO:0045071//negative regulation of viral genome replication;GO:0034340//response to type I interferon;GO:0042742//defense response to bacterium;GO:0019221//cytokine-mediated signaling pathway;GO:0031397//negative regulation of protein ubiquitination;GO:0032020//ISG15-protein conjugation;GO:0016032//viral process;GO:0051607//defense response to virus;GO:0045087//innate immune response;GO:0060337//type I interferon signaling pathway;GO:0032649//regulation of interferon-gamma production;GO:0019941//modification-dependent protein catabolic process;GO:0032480//negative regulation of type I interferon production,GO:0031386//protein tag;GO:0005515//protein binding,K12159//RIG-I-like receptor signaling pathway
9637,0,0,0,13,51,0,0,54,0,0,0,0,FEZ2;fasciculation and elongation protein zeta 2 (zygin II),-,GO:0007399//nervous system development;GO:0007411//axon guidance;GO:0007165//signal transduction,GO:0005515//protein binding,-
9638,0,0,0,0,0,39,30,0,2,0,0,0,FEZ1;fasciculation and elongation protein zeta 1 (zygin I),GO:0005886//plasma membrane;GO:0030425//dendrite;GO:0030424//axon;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0051654//establishment of mitochondrion localization;GO:0010976//positive regulation of neuron projection development;GO:0045666//positive regulation of neuron differentiation;GO:0006810//transport;GO:0007155//cell adhesion;GO:0007411//axon guidance;GO:0071363//cellular response to growth factor stimulus;GO:0007399//nervous system development,GO:0047485//protein N-terminus binding;GO:0043015//gamma-tubulin binding;GO:0005515//protein binding;GO:0005080//protein kinase C binding,K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer;K14443//RNA degradation
9639,28,0,1,0,29,0,97,33,74,142,4,0,ARHGEF10;Rho guanine nucleotide exchange factor (GEF) 10,GO:0005813//centrosome;GO:0005829//cytosol,GO:0051298//centrosome duplication;GO:0032321//positive regulation of Rho GTPase activity;GO:0051496//positive regulation of stress fiber assembly;GO:0090307//spindle assembly involved in mitosis;GO:0022011//myelination in peripheral nervous system;GO:0033126//positive regulation of GTP catabolic process,GO:0019894//kinesin binding;GO:0005515//protein binding;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K05156//Cytokine-cytokine receptor interaction;K08878//Pathways in cancer;Chronic myeloid leukemia;K04436//MAPK signaling pathway
9640,111,0,0,4,17,13,0,71,96,0,0,0,ZNF592;zinc finger protein 592,GO:0005634//nucleus,"GO:0008219//cell death;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
9641,0,0,0,0,0,28,0,28,40,0,1,0,"IKBKE;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005829//cytosol;GO:0010008//endosome membrane;GO:0005730//nucleolus;GO:0016605//PML body,GO:0032480//negative regulation of type I interferon production;GO:0007252//I-kappaB phosphorylation;GO:0034138//toll-like receptor 3 signaling pathway;GO:0043123//positive regulation of I-kappaB kinase/NF-kappaB signaling;GO:0038061//NIK/NF-kappaB signaling;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0045087//innate immune response;GO:0034142//toll-like receptor 4 signaling pathway;GO:0006468//protein phosphorylation;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0008630//intrinsic apoptotic signaling pathway in response to DNA damage;GO:0006955//immune response;GO:0002224//toll-like receptor signaling pathway,GO:0008384//IkappaB kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0004704//NF-kappaB-inducing kinase activity,K07211//Influenza A;RIG-I-like receptor signaling pathway;Toll-like receptor signaling pathway;Measles;Hepatitis C;Cytosolic DNA-sensing pathway;Herpes simplex infection
9643,0,26,1,41,143,0,0,0,1,0,0,0,MORF4L2;mortality factor 4 like 2,GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0051155//positive regulation of striated muscle cell differentiation;GO:0016568//chromatin modification;GO:0006325//chromatin organization;GO:0006281//DNA repair;GO:0006351//transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0040008//regulation of growth",GO:0005515//protein binding,-
9644,0,32,0,6,0,3,2,113,38,0,0,1,SH3PXD2A;SH3 and PX domains 2A,GO:0030054//cell junction;GO:0002102//podosome;GO:0005737//cytoplasm;GO:0042995//cell projection,GO:0006801//superoxide metabolic process,GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding,K08011//Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Chemokine signaling pathway;Leishmaniasis;Osteoclast differentiation;Phagosome
9645,33,0,0,4,9,26,34,70,80,3,14,0,"MICAL2;microtubule associated monooxygenase, calponin and LIM domain containing 2",GO:0005634//nucleus,GO:0007010//cytoskeleton organization;GO:0019417//sulfur oxidation;GO:0007507//heart development;GO:0030042//actin filament depolymerization;GO:0010735//positive regulation of transcription via serum response element binding;GO:0001947//heart looping;GO:0055114//oxidation-reduction process,"GO:0071949//FAD binding;GO:0008270//zinc ion binding;GO:0043914//NADPH:sulfur oxidoreductase activity;GO:0003779//actin binding;GO:0016709//oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen",K05699//Systemic lupus erythematosus;Regulation of actin cytoskeleton;Adherens junction;Amoebiasis;Focal adhesion;Tight junction;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Leukocyte transendothelial migration
96459,0,33,0,1,93,21,29,0,29,0,0,0,FNIP1;folliculin interacting protein 1,GO:0005737//cytoplasm,GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0001932//regulation of protein phosphorylation;GO:0002904//positive regulation of B cell apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0002327//immature B cell differentiation;GO:0032007//negative regulation of TOR signaling;GO:0009267//cellular response to starvation;GO:0031929//TOR signaling;GO:0043547//positive regulation of GTPase activity;GO:2000973//regulation of pro-B cell differentiation;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005085//guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
9646,0,33,0,35,78,0,71,380,21,0,1,0,"CTR9;CTR9, Paf1/RNA polymerase II complex component",GO:0035327//transcriptionally active chromatin;GO:0016607//nuclear speck;GO:0016593//Cdc73/Paf1 complex,"GO:0032968//positive regulation of transcription elongation from RNA polymerase II promoter;GO:0033523//histone H2B ubiquitination;GO:0051571//positive regulation of histone H3-K4 methylation;GO:0001711//endodermal cell fate commitment;GO:0019827//stem cell maintenance;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0071222//cellular response to lipopolysaccharide;GO:0016055//Wnt signaling pathway;GO:0070102//interleukin-6-mediated signaling pathway;GO:0007259//JAK-STAT cascade;GO:2001162//positive regulation of histone H3-K79 methylation;GO:0010390//histone monoubiquitination;GO:0006351//transcription, DNA-templated;GO:0080182//histone H3-K4 trimethylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045638//negative regulation of myeloid cell differentiation",GO:0042169//SH2 domain binding;GO:0005515//protein binding,-
9647,100,0,0,18,23,0,0,162,21,114,11,0,"PPM1F;protein phosphatase, Mg2+/Mn2+ dependent, 1F",GO:0043234//protein complex;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol,"GO:0010634//positive regulation of epithelial cell migration;GO:0044387//negative regulation of protein kinase activity by regulation of protein phosphorylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0051496//positive regulation of stress fiber assembly;GO:0016576//histone dephosphorylation;GO:0051894//positive regulation of focal adhesion assembly;GO:0035690//cellular response to drug;GO:0050921//positive regulation of chemotaxis;GO:0043280//positive regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0010811//positive regulation of cell-substrate adhesion;GO:0010628//positive regulation of gene expression;GO:0097193//intrinsic apoptotic signaling pathway;GO:0033137//negative regulation of peptidyl-serine phosphorylation;GO:0035970//peptidyl-threonine dephosphorylation;GO:0006469//negative regulation of protein kinase activity;GO:0045927//positive regulation of growth",GO:0033192//calmodulin-dependent protein phosphatase activity;GO:0004722//protein serine/threonine phosphatase activity;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0016791//phosphatase activity,-
9648,0,23,25,61,165,23,19,0,64,208,19,0,GCC2;GRIP and coiled-coil domain containing 2,GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005802//trans-Golgi network;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006622//protein targeting to lysosome;GO:0034067//protein localization to Golgi apparatus;GO:0000042//protein targeting to Golgi;GO:0042147//retrograde transport, endosome to Golgi;GO:0070861//regulation of protein exit from endoplasmic reticulum;GO:0034453//microtubule anchoring;GO:0034499//late endosome to Golgi transport;GO:0031023//microtubule organizing center organization;GO:0071955//recycling endosome to Golgi transport;GO:0090161//Golgi ribbon formation;GO:0043001//Golgi to plasma membrane protein transport",GO:0005515//protein binding;GO:0042802//identical protein binding,-
9649,1,0,0,33,17,20,4,0,65,0,13,0,RALGPS1;Ral GEF with PH domain and SH3 binding motif 1,GO:0005737//cytoplasm;GO:0005886//plasma membrane,GO:0035556//intracellular signal transduction;GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction,GO:0008321//Ral guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K12326//MAPK signaling pathway;K04349//Focal adhesion;MAPK signaling pathway;K03099//Fc epsilon RI signaling pathway;Jak-STAT signaling pathway;Acute myeloid leukemia;B cell receptor signaling pathway;Regulation of actin cytoskeleton;Hepatitis C;Neurotrophin signaling pathway;Non-small cell lung cancer;Endometrial cancer;MAPK signaling pathway - fly;Focal adhesion;Dorso-ventral axis formation;Glioma;Insulin signaling pathway;Gap junction;Pathways in cancer;GnRH signaling pathway;Chemokine signaling pathway;Alcoholism;Prostate cancer;Chronic myeloid leukemia;Natural killer cell mediated cytotoxicity;MAPK signaling pathway;T cell receptor signaling pathway;Renal cell carcinoma;ErbB signaling pathway
965,104,0,0,0,0,0,0,0,11,0,12,0,CD58;CD58 molecule,GO:0031225//anchored component of membrane;GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0016020//membrane,GO:0071356//cellular response to tumor necrosis factor;GO:0050900//leukocyte migration;GO:0071346//cellular response to interferon-gamma;GO:0007155//cell adhesion;GO:0016337//single organismal cell-cell adhesion;GO:0007596//blood coagulation;GO:2000484//positive regulation of interleukin-8 secretion;GO:0034113//heterotypic cell-cell adhesion,GO:0005515//protein binding;GO:0005102//receptor binding,K06492//Cell adhesion molecules (CAMs);Epstein-Barr virus infection
9650,0,1,0,13,1,11,0,0,1,0,1,0,MTFR1;mitochondrial fission regulator 1,GO:0005886//plasma membrane;GO:0005739//mitochondrion;GO:0005737//cytoplasm,GO:0000266//mitochondrial fission;GO:0007005//mitochondrion organization;GO:0009060//aerobic respiration,-,-
9651,25,0,0,0,1,5,0,120,31,0,4,0,"PLCH2;phospholipase C, eta 2",GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0046488//phosphatidylinositol metabolic process;GO:0044281//small molecule metabolic process;GO:0016042//lipid catabolic process;GO:0043647//inositol phosphate metabolic process;GO:0035556//intracellular signal transduction,GO:0004435//phosphatidylinositol phospholipase C activity;GO:0005509//calcium ion binding;GO:0004871//signal transducer activity,-
9652,0,0,0,49,163,0,1,0,100,0,5,55,TTC37;tetratricopeptide repeat domain 37,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0055087//Ski complex;GO:0005730//nucleolus;GO:0035327//transcriptionally active chromatin,-,GO:0005515//protein binding,K12600//RNA degradation
9653,79,0,0,8,30,0,20,0,36,0,4,0,HS2ST1;heparan sulfate 2-O-sulfotransferase 1,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process,GO:0008146//sulfotransferase activity,K02513//Glycosaminoglycan biosynthesis - heparan sulfate
9654,0,37,23,4,22,0,5,0,61,98,27,0,"TTLL4;tubulin tyrosine ligase-like family, member 4",GO:0005856//cytoskeleton;GO:0005737//cytoplasm;GO:0005929//cilium,GO:0018095//protein polyglutamylation,GO:0015631//tubulin binding;GO:0016874//ligase activity,"K06228//Pathways in cancer;Hedgehog signaling pathway;Basal cell carcinoma;K00273//Metabolic pathways;Penicillin and cephalosporin biosynthesis;Glycine, serine and threonine metabolism;Peroxisome;D-Arginine and D-ornithine metabolism;Arginine and proline metabolism"
9655,0,7,1,0,23,8,0,0,7,0,2,0,SOCS5;suppressor of cytokine signaling 5,-,GO:0045629//negative regulation of T-helper 2 cell differentiation;GO:0007259//JAK-STAT cascade;GO:0032436//positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0016049//cell growth;GO:0007175//negative regulation of epidermal growth factor-activated receptor activity;GO:0045627//positive regulation of T-helper 1 cell differentiation;GO:0016567//protein ubiquitination;GO:0019221//cytokine-mediated signaling pathway;GO:0009968//negative regulation of signal transduction;GO:0040008//regulation of growth,GO:0005515//protein binding;GO:0030971//receptor tyrosine kinase binding;GO:0005154//epidermal growth factor receptor binding,K04698//Jak-STAT signaling pathway
9657,51,0,1,0,0,0,0,0,23,0,2,0,IQCB1;IQ motif containing B1,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0001750//photoreceptor outer segment;GO:0005634//nucleus;GO:0032391//photoreceptor connecting cilium;GO:0015630//microtubule cytoskeleton;GO:0005730//nucleolus;GO:0045171//intercellular bridge,GO:0042384//cilium assembly;GO:0045494//photoreceptor cell maintenance;GO:0048496//maintenance of organ identity,GO:0019899//enzyme binding;GO:0005516//calmodulin binding;GO:0005515//protein binding,-
9658,0,0,0,0,0,23,0,2,33,2,0,0,ZNF516;zinc finger protein 516,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
9659,84,50,44,18,10,151,153,41,264,190,23,119,PDE4DIP;phosphodiesterase 4D interacting protein,GO:0030016//myofibril;GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0043623//cellular protein complex assembly,GO:0005515//protein binding;GO:0019899//enzyme binding,K01509//Purine metabolism;K10352//Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K12478//Tuberculosis;Phagosome;Endocytosis
966,0,0,0,0,32,0,0,0,18,0,0,0,"CD59;CD59 molecule, complement regulatory protein",GO:0031982//vesicle;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0016020//membrane;GO:0009986//cell surface;GO:0031362//anchored component of external side of plasma membrane;GO:0042383//sarcolemma;GO:0005925//focal adhesion;GO:0005615//extracellular space;GO:0043218//compact myelin,GO:0030449//regulation of complement activation;GO:0045087//innate immune response;GO:0001971//negative regulation of activation of membrane attack complex;GO:0042102//positive regulation of T cell proliferation;GO:0043066//negative regulation of apoptotic process;GO:0007596//blood coagulation;GO:0001775//cell activation;GO:0007166//cell surface receptor signaling pathway,GO:0001848//complement binding;GO:0005515//protein binding,K04008//Hematopoietic cell lineage;Complement and coagulation cascades
96610,0,0,0,0,0,0,0,0,20,0,0,0,BMS1P20;BMS1 pseudogene 20,-,-,-,K14569//Ribosome biogenesis in eukaryotes
9662,1,0,0,7,0,19,0,0,42,13,0,0,CEP135;centrosomal protein 135kDa,GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome,GO:0010457//centriole-centriole cohesion;GO:0000278//mitotic cell cycle;GO:0007099//centriole replication;GO:0000086//G2/M transition of mitotic cell cycle,GO:0008022//protein C-terminus binding;GO:0005515//protein binding,K12478//Phagosome;Endocytosis;Tuberculosis
9663,215,24,0,35,83,28,40,51,55,98,24,0,LPIN2;lipin 2,GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane;GO:0005634//nucleus,"GO:0006629//lipid metabolic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0044255//cellular lipid metabolic process;GO:0006644//phospholipid metabolic process;GO:0019432//triglyceride biosynthetic process;GO:0044281//small molecule metabolic process;GO:0016311//dephosphorylation;GO:0006351//transcription, DNA-templated;GO:0006646//phosphatidylethanolamine biosynthetic process;GO:0006631//fatty acid metabolic process;GO:0006656//phosphatidylcholine biosynthetic process",GO:0008195//phosphatidate phosphatase activity;GO:0003713//transcription coactivator activity,K15728//Glycerolipid metabolism;Metabolic pathways;Glycerophospholipid metabolism
9665,0,72,2,50,177,72,0,0,44,0,12,0,KIAA0430;KIAA0430,GO:0016020//membrane;GO:0005777//peroxisome,GO:0007143//female meiotic division;GO:0006302//double-strand break repair;GO:0048477//oogenesis;GO:0010468//regulation of gene expression;GO:0010923//negative regulation of phosphatase activity,GO:0003723//RNA binding;GO:0000166//nucleotide binding,-
9666,0,16,0,12,81,27,0,2,57,0,0,0,DZIP3;DAZ interacting zinc finger protein 3,GO:0005737//cytoplasm,GO:0000209//protein polyubiquitination,GO:0019902//phosphatase binding;GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0044822//poly(A) RNA binding;GO:0016874//ligase activity;GO:0031593//polyubiquitin binding;GO:0003723//RNA binding,-
9667,0,0,0,2,10,17,0,0,36,0,0,0,SAFB2;scaffold attachment factor B2,GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0042802//identical protein binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0003677//DNA binding,K14411//mRNA surveillance pathway;K12897//Spliceosome
9668,22,0,1,11,40,0,0,0,23,0,0,0,ZNF432;zinc finger protein 432,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9669,0,1,0,0,169,22,0,0,57,0,13,0,EIF5B;eukaryotic translation initiation factor 5B,GO:0005829//cytosol,GO:0010467//gene expression;GO:0044267//cellular protein metabolic process;GO:0006413//translational initiation;GO:0006184//GTP catabolic process;GO:0006412//translation;GO:0006446//regulation of translational initiation,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005525//GTP binding;GO:0003924//GTPase activity;GO:0003743//translation initiation factor activity,K03243//RNA transport
967,0,141,98,114,226,0,0,678,87,0,272,0,CD63;CD63 molecule,"GO:0031902//late endosome membrane;GO:0005887//integral component of plasma membrane;GO:0097487//multivesicular body, internal vesicle;GO:0005765//lysosomal membrane;GO:0031088//platelet dense granule membrane;GO:0031226//intrinsic component of plasma membrane;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0009986//cell surface;GO:0010008//endosome membrane;GO:0042470//melanosome",GO:0002576//platelet degranulation;GO:0015031//protein transport;GO:0002092//positive regulation of receptor internalization;GO:2001046//positive regulation of integrin-mediated signaling pathway;GO:0007160//cell-matrix adhesion;GO:0034613//cellular protein localization;GO:0035646//endosome to melanosome transport;GO:0007596//blood coagulation;GO:0030168//platelet activation;GO:2000680//regulation of rubidium ion transport;GO:0016477//cell migration;GO:1900746//regulation of vascular endothelial growth factor signaling pathway,GO:0005515//protein binding,K06497//Lysosome
9670,0,0,0,1,1,19,38,0,23,0,20,0,IPO13;importin 13,GO:0005634//nucleus;GO:0005737//cytoplasm,GO:0006606//protein import into nucleus,GO:0005515//protein binding;GO:0008536//Ran GTPase binding,-
9671,0,0,0,0,0,11,25,0,33,0,9,0,WSCD2;WSC domain containing 2,GO:0016021//integral component of membrane,-,-,K12594//RNA degradation;K00771//Glycosaminoglycan biosynthesis - chondroitin sulfate;Metabolic pathways;Glycosaminoglycan biosynthesis - heparan sulfate
9672,2,0,0,0,6,29,36,0,51,0,0,127,SDC3;syndecan 3,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005796//Golgi lumen;GO:0005886//plasma membrane;GO:0043202//lysosomal lumen,"GO:0005975//carbohydrate metabolic process;GO:0001523//retinoid metabolic process;GO:0030198//extracellular matrix organization;GO:0006024//glycosaminoglycan biosynthetic process;GO:0030203//glycosaminoglycan metabolic process;GO:0044281//small molecule metabolic process;GO:0007603//phototransduction, visible light;GO:0006027//glycosaminoglycan catabolic process;GO:0030204//chondroitin sulfate metabolic process",GO:0008092//cytoskeletal protein binding,K06257//ECM-receptor interaction;Malaria;Cell adhesion molecules (CAMs)
9673,0,41,0,5,16,1,0,75,10,0,0,0,"SLC25A44;solute carrier family 25, member 44",GO:0016021//integral component of membrane;GO:0005743//mitochondrial inner membrane,GO:0055085//transmembrane transport,-,-
9674,0,0,1,0,0,0,0,0,8,0,0,0,KIAA0040;KIAA0040,-,-,-,-
9675,0,25,2,4,22,0,11,0,27,0,0,0,TTI1;TELO2 interacting protein 1,GO:0031932//TORC2 complex;GO:0031931//TORC1 complex;GO:0005737//cytoplasm,GO:0032006//regulation of TOR signaling,GO:0005515//protein binding,-
96764,0,0,0,8,52,66,0,0,40,0,9,0,TGS1;trimethylguanosine synthase 1,GO:0005615//extracellular space;GO:0030532//small nuclear ribonucleoprotein complex;GO:0005829//cytosol;GO:0015030//Cajal body;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0044255//cellular lipid metabolic process;GO:0044281//small molecule metabolic process;GO:0071167//ribonucleoprotein complex import into nucleus;GO:0006355//regulation of transcription, DNA-templated;GO:0016070//RNA metabolic process;GO:0036261//7-methylguanosine cap hypermethylation;GO:0034660//ncRNA metabolic process;GO:0000387//spliceosomal snRNP assembly;GO:0006351//transcription, DNA-templated;GO:0009452//7-methylguanosine RNA capping;GO:0010467//gene expression",GO:0071164//RNA trimethylguanosine synthase activity;GO:0005515//protein binding,K14292//RNA transport
9677,16,1,2,10,3,27,85,14,88,0,0,50,PPIP5K1;diphosphoinositol pentakisphosphate kinase 1,GO:0005886//plasma membrane;GO:0005829//cytosol,GO:0006020//inositol metabolic process;GO:0016311//dephosphorylation;GO:0016310//phosphorylation;GO:0043647//inositol phosphate metabolic process;GO:0044281//small molecule metabolic process,"GO:0000827//inositol-1,3,4,5,6-pentakisphosphate kinase activity;GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0003993//acid phosphatase activity;GO:0005524//ATP binding;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0033857//diphosphoinositol-pentakisphosphate kinase activity",-
9678,0,0,0,24,60,34,40,0,137,0,0,0,PHF14;PHD finger protein 14,GO:0005634//nucleus,GO:2000584//negative regulation of platelet-derived growth factor receptor-alpha signaling pathway;GO:0048286//lung alveolus development;GO:2000791//negative regulation of mesenchymal cell proliferation involved in lung development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter,GO:0008270//zinc ion binding,-
9679,0,0,19,0,20,0,4,0,55,0,49,44,"FAM53B;family with sequence similarity 53, member B",-,-,-,-
968,0,61,0,25,12,22,14,25,0,6,12,0,CD68;CD68 molecule,GO:0005765//lysosomal membrane;GO:0010008//endosome membrane;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0071310//cellular response to organic substance,-,K06501//Lysosome
9681,0,0,0,0,10,31,26,0,113,0,9,0,DEPDC5;DEP domain containing 5,GO:0048471//perinuclear region of cytoplasm;GO:0005765//lysosomal membrane;GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0035556//intracellular signal transduction,GO:0005096//GTPase activator activity,-
9682,51,62,1,5,74,35,0,43,48,0,39,256,KDM4A;lysine (K)-specific demethylase 4A,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0016032//viral process;GO:0070544//histone H3-K36 demethylation;GO:0055114//oxidation-reduction process;GO:0014898//cardiac muscle hypertrophy in response to stress;GO:0006351//transcription, DNA-templated;GO:0045892//negative regulation of transcription, DNA-templated",GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0035064//methylated histone binding;GO:0008270//zinc ion binding;GO:0051864//histone demethylase activity (H3-K36 specific),-
9683,0,0,0,19,58,55,16,0,31,0,10,0,N4BP1;NEDD4 binding protein 1,GO:0016605//PML body;GO:0005730//nucleolus,GO:0034644//cellular response to UV;GO:0032435//negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0031397//negative regulation of protein ubiquitination,GO:0005515//protein binding,-
9684,91,258,656,297,783,13,0,1310,208,2,3959,1,LRRC14;leucine rich repeat containing 14,-,-,-,-
9685,0,1,1,32,67,0,0,58,29,0,0,0,CLINT1;clathrin interactor 1,GO:0005794//Golgi apparatus;GO:0030136//clathrin-coated vesicle;GO:0016020//membrane;GO:0005730//nucleolus;GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0006897//endocytosis;GO:0006892//post-Golgi vesicle-mediated transport;GO:0061024//membrane organization;GO:0048268//clathrin coat assembly,GO:0005515//protein binding;GO:0008289//lipid binding;GO:0030276//clathrin binding,K12471//Endocytosis;K11137//Fanconi anemia pathway
9686,77,48,47,94,145,69,64,0,0,0,69,0,VGLL4;vestigial-like family member 4,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",-,-
9687,0,175,29,123,395,24,96,0,139,181,25,145,GREB1;growth regulation by estrogen in breast cancer 1,GO:0016021//integral component of membrane,-,-,K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K06264//ECM-receptor interaction;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
9688,58,0,0,1,16,0,24,44,42,0,11,0,NUP93;nucleoporin 93kDa,GO:0016020//membrane;GO:0005643//nuclear pore;GO:0005635//nuclear envelope;GO:0034399//nuclear periphery;GO:0031965//nuclear membrane,GO:0055085//transmembrane transport;GO:0000278//mitotic cell cycle;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0015758//glucose transport;GO:0044281//small molecule metabolic process;GO:0051292//nuclear pore complex assembly;GO:0005975//carbohydrate metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport,GO:0017056//structural constituent of nuclear pore,K14309//RNA transport
9689,0,158,3,275,619,11,4,0,86,0,1,5,BZW1;basic leucine zipper and W2 domains 1,GO:0005737//cytoplasm;GO:0016020//membrane,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0044822//poly(A) RNA binding,K03240//RNA transport;K03260//Viral myocarditis;RNA transport
969,0,0,0,0,0,0,0,0,7,0,0,0,CD69;CD69 molecule,GO:0005887//integral component of plasma membrane;GO:0009897//external side of plasma membrane,GO:0035690//cellular response to drug;GO:0007165//signal transduction,GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0030246//carbohydrate binding,-
9690,1,36,1,9,41,0,0,0,52,0,0,0,UBE3C;ubiquitin protein ligase E3C,GO:0000502//proteasome complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005622//intracellular,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0000209//protein polyubiquitination,GO:0016874//ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K10589//Ubiquitin mediated proteolysis
9692,0,192,188,163,157,0,26,143,38,0,161,0,KIAA0391;KIAA0391,GO:0005739//mitochondrion,GO:0008033//tRNA processing,-,-
9693,0,21,0,32,28,45,20,0,39,0,0,0,RAPGEF2;Rap guanine nucleotide exchange factor (GEF) 2,GO:0005887//integral component of plasma membrane;GO:0048471//perinuclear region of cytoplasm;GO:0043234//protein complex;GO:0005911//cell-cell junction;GO:0043025//neuronal cell body;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0016020//membrane;GO:0005770//late endosome;GO:0045202//synapse;GO:0005886//plasma membrane,GO:0032486//Rap protein signal transduction;GO:0010976//positive regulation of neuron projection development;GO:0045860//positive regulation of protein kinase activity;GO:0021591//ventricular system development;GO:0031547//brain-derived neurotrophic factor receptor signaling pathway;GO:1990090//cellular response to nerve growth factor stimulus;GO:0071321//cellular response to cGMP;GO:0032320//positive regulation of Ras GTPase activity;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0031175//neuron projection development;GO:0071880//adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0048022//negative regulation of melanin biosynthetic process;GO:0061028//establishment of endothelial barrier;GO:0019933//cAMP-mediated signaling;GO:0007186//G-protein coupled receptor signaling pathway;GO:0048167//regulation of synaptic plasticity;GO:0000165//MAPK cascade;GO:2001224//positive regulation of neuron migration;GO:0007218//neuropeptide signaling pathway;GO:2001214//positive regulation of vasculogenesis;GO:0050774//negative regulation of dendrite morphogenesis;GO:2000481//positive regulation of cAMP-dependent protein kinase activity;GO:2000670//positive regulation of dendritic cell apoptotic process;GO:0001764//neuron migration;GO:0071320//cellular response to cAMP;GO:0001568//blood vessel development;GO:1901888//regulation of cell junction assembly;GO:0038180//nerve growth factor signaling pathway;GO:0043950//positive regulation of cAMP-mediated signaling;GO:0007264//small GTPase mediated signal transduction;GO:0021884//forebrain neuron development;GO:0035556//intracellular signal transduction;GO:0032854//positive regulation of Rap GTPase activity;GO:0008285//negative regulation of cell proliferation;GO:0032092//positive regulation of protein binding,GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0031697//beta-1 adrenergic receptor binding;GO:0030552//cAMP binding;GO:0019901//protein kinase binding;GO:0046582//Rap GTPase activator activity;GO:0030553//cGMP binding;GO:0004871//signal transducer activity;GO:0017034//Rap guanyl-nucleotide exchange factor activity;GO:0050699//WW domain binding;GO:0019992//diacylglycerol binding;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,K08018//MAPK signaling pathway
9694,105,0,0,0,0,0,0,0,47,0,0,0,EMC2;ER membrane protein complex subunit 2,GO:0072546//ER membrane protein complex;GO:0005783//endoplasmic reticulum;GO:0005739//mitochondrion;GO:0005634//nucleus;GO:0005737//cytoplasm,-,-,-
9695,0,0,0,1,13,0,0,0,35,0,12,0,"EDEM1;ER degradation enhancer, mannosidase alpha-like 1",GO:0005789//endoplasmic reticulum membrane;GO:0030176//integral component of endoplasmic reticulum membrane,GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0030433//ER-associated ubiquitin-dependent protein catabolic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006457//protein folding,"GO:0004571//mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;GO:0005515//protein binding;GO:0051787//misfolded protein binding;GO:0005509//calcium ion binding",K10084//Protein processing in endoplasmic reticulum
9696,17,1,0,0,0,40,3,0,105,230,11,1,"CROCC;ciliary rootlet coiled-coil, rootletin",GO:0035253//ciliary rootlet;GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0015629//actin cytoskeleton;GO:0005814//centriole;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0010457//centriole-centriole cohesion;GO:0030030//cell projection organization;GO:0008104//protein localization;GO:0007049//cell cycle;GO:0033365//protein localization to organelle;GO:0051297//centrosome organization,GO:0019894//kinesin binding;GO:0005515//protein binding;GO:0005198//structural molecule activity,K10352//Cardiac muscle contraction;Dilated cardiomyopathy;Salmonella infection;Tight junction;Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM)
9697,0,0,0,0,0,0,0,77,94,0,0,0,TRAM2;translocation associated membrane protein 2,GO:0016021//integral component of membrane,GO:0015031//protein transport;GO:0032964//collagen biosynthetic process,GO:0005515//protein binding,K14010//Protein processing in endoplasmic reticulum
9698,55,51,1,38,111,17,0,0,44,211,2,0,PUM1;pumilio RNA-binding family member 1,GO:0005829//cytosol,GO:0006892//post-Golgi vesicle-mediated transport;GO:0006417//regulation of translation;GO:0061024//membrane organization,GO:0044822//poly(A) RNA binding,-
9699,30,0,0,26,32,0,0,0,10,0,11,0,RIMS2;regulating synaptic membrane exocytosis 2,GO:0030054//cell junction;GO:0042734//presynaptic membrane;GO:0048786//presynaptic active zone,GO:0017157//regulation of exocytosis;GO:0017156//calcium ion-dependent exocytosis;GO:0097151//positive regulation of inhibitory postsynaptic membrane potential;GO:0019933//cAMP-mediated signaling;GO:0010628//positive regulation of gene expression;GO:0030073//insulin secretion;GO:0006886//intracellular protein transport;GO:0048791//calcium ion-dependent exocytosis of neurotransmitter,GO:0017137//Rab GTPase binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0044325//ion channel binding,-
97,0,0,0,0,0,0,0,69,0,0,7,0,"ACYP1;acylphosphatase 1, erythrocyte (common) type",GO:0070062//extracellular vesicular exosome,GO:0006796//phosphate-containing compound metabolic process,GO:0003998//acylphosphatase activity,K01512//Aminobenzoate degradation;Pyrimidine metabolism;Pyruvate metabolism;Microbial metabolism in diverse environments;Metabolic pathways
970,0,0,0,0,0,13,0,0,12,0,0,0,CD70;CD70 molecule,GO:0005887//integral component of plasma membrane;GO:0005615//extracellular space;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007165//signal transduction;GO:0097191//extrinsic apoptotic signaling pathway;GO:0007267//cell-cell signaling;GO:0006955//immune response;GO:0008283//cell proliferation,GO:0005102//receptor binding;GO:0002020//protease binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005515//protein binding;GO:0005125//cytokine activity,K05470//Cytokine-cytokine receptor interaction
9700,90,0,110,7,0,12,23,0,18,2,22,0,ESPL1;extra spindle pole bodies homolog 1 (S. cerevisiae),GO:0005829//cytosol;GO:0005634//nucleus;GO:0005813//centrosome,GO:0045875//negative regulation of sister chromatid cohesion;GO:0000278//mitotic cell cycle;GO:0006508//proteolysis;GO:0045143//homologous chromosome segregation;GO:0000070//mitotic sister chromatid segregation;GO:0006915//apoptotic process;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0040001//establishment of mitotic spindle localization;GO:0000910//cytokinesis;GO:0000212//meiotic spindle organization,GO:0003824//catalytic activity;GO:0005515//protein binding;GO:0008234//cysteine-type peptidase activity,K02365//Oocyte meiosis;Meiosis - yeast;Cell cycle;Cell cycle - yeast
9701,0,47,1,26,70,27,16,3,61,0,53,0,"PPP6R2;protein phosphatase 6, regulatory subunit 2",GO:0005737//cytoplasm;GO:0043231//intracellular membrane-bounded organelle,-,GO:0005515//protein binding,-
9702,0,0,2,23,136,26,0,63,32,205,13,0,CEP57;centrosomal protein 57kDa,GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0015630//microtubule cytoskeleton;GO:0005874//microtubule;GO:0005634//nucleus,"GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0034453//microtubule anchoring;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0007286//spermatid development;GO:0051260//protein homooligomerization;GO:0000060//protein import into nucleus, translocation",GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0042803//protein homodimerization activity;GO:0043015//gamma-tubulin binding;GO:0017134//fibroblast growth factor binding,K10352//Vascular smooth muscle contraction;Regulation of actin cytoskeleton;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Salmonella infection;Tight junction;Cardiac muscle contraction;Dilated cardiomyopathy;K11423//Lysine degradation
9703,83,2,20,33,106,2,13,126,98,432,24,76,KIAA0100;KIAA0100,GO:0005576//extracellular region,-,-,-
9704,0,0,0,9,13,0,0,0,45,0,0,0,DHX34;DEAH (Asp-Glu-Ala-His) box polypeptide 34,GO:0016020//membrane,"GO:2000623//negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000956//nuclear-transcribed mRNA catabolic process",GO:0004386//helicase activity;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding,K12818//Spliceosome
9705,0,0,0,15,1,6,0,0,32,0,2,0,"ST18;suppression of tumorigenicity 18, zinc finger",GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding;GO:0008270//zinc ion binding,-
9706,0,2,1,0,10,0,30,51,45,54,8,0,ULK2;unc-51 like autophagy activating kinase 2,GO:0005829//cytosol;GO:0030659//cytoplasmic vesicle membrane;GO:0034045//pre-autophagosomal structure membrane;GO:0034273//ATG1/UKL1 signaling complex,GO:0007165//signal transduction;GO:0046777//protein autophosphorylation;GO:0048671//negative regulation of collateral sprouting;GO:0010506//regulation of autophagy;GO:0048675//axon extension;GO:0042594//response to starvation;GO:0000045//autophagic vacuole assembly,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,K08269//mTOR signaling pathway;Regulation of autophagy
9708,0,0,0,0,8,0,0,11,0,0,12,0,"PCDHGA8;protocadherin gamma subfamily A, 8",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
9709,0,1,2,12,104,30,0,0,9,0,0,0,"HERPUD1;homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1",GO:0005789//endoplasmic reticulum membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0030968//endoplasmic reticulum unfolded protein response;GO:0031396//regulation of protein ubiquitination;GO:0006874//cellular calcium ion homeostasis;GO:0006986//response to unfolded protein;GO:0043154//negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process;GO:0032092//positive regulation of protein binding;GO:0006987//activation of signaling protein activity involved in unfolded protein response,-,K14027//Protein processing in endoplasmic reticulum
971,0,0,0,0,0,41,0,0,24,0,30,0,CD72;CD72 molecule,GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane,GO:0007411//axon guidance;GO:0007165//signal transduction;GO:0007155//cell adhesion,GO:0030246//carbohydrate binding;GO:0005515//protein binding;GO:0004888//transmembrane signaling receptor activity;GO:0005102//receptor binding,K06504//B cell receptor signaling pathway
9710,0,19,0,7,17,7,18,68,29,0,11,0,KIAA0355;KIAA0355,-,-,-,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
9711,0,0,0,0,19,0,54,1,23,0,13,260,KIAA0226;KIAA0226,GO:0005770//late endosome;GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005764//lysosome,GO:0006897//endocytosis;GO:0006914//autophagy;GO:0010507//negative regulation of autophagy;GO:0045806//negative regulation of endocytosis,GO:0005515//protein binding,K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K01539//Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Carbohydrate digestion and absorption;Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;K11447//Transcriptional misregulation in cancer
9712,0,0,0,0,38,11,53,0,84,0,0,0,USP6NL;USP6 N-terminal like,GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0031410//cytoplasmic vesicle,"GO:0048227//plasma membrane to endosome transport;GO:0007030//Golgi organization;GO:0019068//virion assembly;GO:0032851//positive regulation of Rab GTPase activity;GO:1902017//regulation of cilium assembly;GO:0035526//retrograde transport, plasma membrane to Golgi;GO:0033126//positive regulation of GTP catabolic process",GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding,K13136//RNA transport
9715,0,0,0,0,0,3,29,0,25,50,6,0,"FAM131B;family with sequence similarity 131, member B",-,-,-,-
9716,112,28,0,8,84,19,8,0,90,2,0,0,AQR;aquarius intron-binding spliceosomal factor,GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0005634//nucleus,"GO:0000398//mRNA splicing, via spliceosome",GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K12874//Spliceosome
9717,0,0,0,0,1,0,0,0,86,0,12,0,SEC14L5;SEC14-like 5 (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005622//intracellular,GO:0006810//transport,GO:0005215//transporter activity,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
9718,0,0,0,0,0,0,0,45,48,0,0,131,ECE2;endothelin converting enzyme 2,GO:0030659//cytoplasmic vesicle membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0016486//peptide hormone processing;GO:0007267//cell-cell signaling;GO:0010002//cardioblast differentiation;GO:0007420//brain development;GO:0007507//heart development;GO:0006508//proteolysis;GO:0032259//methylation,GO:0008168//methyltransferase activity;GO:0004222//metalloendopeptidase activity;GO:0046872//metal ion binding,-
9719,0,0,0,0,0,20,19,0,27,1,22,0,ADAMTSL2;ADAMTS-like 2,GO:0005578//proteinaceous extracellular matrix,GO:0006508//proteolysis;GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway,GO:0008270//zinc ion binding;GO:0005515//protein binding;GO:0004222//metalloendopeptidase activity,-
972,0,0,0,0,3,64,25,0,0,0,0,0,"CD74;CD74 molecule, major histocompatibility complex, class II invariant chain",GO:0016021//integral component of membrane;GO:0005886//plasma membrane;GO:0035693//NOS2-CD74 complex;GO:0012507//ER to Golgi transport vesicle membrane;GO:0035692//macrophage migration inhibitory factor receptor complex;GO:0032588//trans-Golgi network membrane;GO:0005622//intracellular;GO:0042613//MHC class II protein complex;GO:0030658//transport vesicle membrane;GO:0005765//lysosomal membrane;GO:0043202//lysosomal lumen;GO:0000139//Golgi membrane;GO:0005773//vacuole;GO:0009986//cell surface;GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0030669//clathrin-coated endocytic vesicle membrane;GO:0071556//integral component of lumenal side of endoplasmic reticulum membrane;GO:0005771//multivesicular body;GO:0030666//endocytic vesicle membrane,"GO:0043066//negative regulation of apoptotic process;GO:0048146//positive regulation of fibroblast proliferation;GO:0008283//cell proliferation;GO:0050731//positive regulation of peptidyl-tyrosine phosphorylation;GO:0016064//immunoglobulin mediated immune response;GO:0060907//positive regulation of macrophage cytokine production;GO:0006952//defense response;GO:0006461//protein complex assembly;GO:0002830//positive regulation of type 2 immune response;GO:0002906//negative regulation of mature B cell apoptotic process;GO:0043030//regulation of macrophage activation;GO:0006886//intracellular protein transport;GO:0001961//positive regulation of cytokine-mediated signaling pathway;GO:0019883//antigen processing and presentation of endogenous antigen;GO:0090023//positive regulation of neutrophil chemotaxis;GO:0035691//macrophage migration inhibitory factor signaling pathway;GO:0002792//negative regulation of peptide secretion;GO:0002606//positive regulation of dendritic cell antigen processing and presentation;GO:2000343//positive regulation of chemokine (C-X-C motif) ligand 2 production;GO:0045058//T cell selection;GO:0000187//activation of MAPK activity;GO:1902166//negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator;GO:0030890//positive regulation of B cell proliferation;GO:0045059//positive thymic T cell selection;GO:0045060//negative thymic T cell selection;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0045581//negative regulation of T cell differentiation;GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0001516//prostaglandin biosynthetic process;GO:0007165//signal transduction;GO:0043518//negative regulation of DNA damage response, signal transduction by p53 class mediator;GO:0045582//positive regulation of T cell differentiation;GO:0051085//chaperone mediated protein folding requiring cofactor","GO:0042289//MHC class II protein binding;GO:0001540//beta-amyloid binding;GO:0004896//cytokine receptor activity;GO:0042658//MHC class II protein binding, via antigen binding groove;GO:0044183//protein binding involved in protein folding;GO:0023026//MHC class II protein complex binding;GO:0005515//protein binding;GO:0050998//nitric-oxide synthase binding;GO:0019955//cytokine binding;GO:0035718//macrophage migration inhibitory factor binding;GO:0042802//identical protein binding",K06505//Herpes simplex infection;Tuberculosis;Antigen processing and presentation
9720,0,0,0,0,0,15,64,0,55,0,0,0,CCDC144A;coiled-coil domain containing 144A,-,-,-,K10352//Tight junction;Salmonella infection;Dilated cardiomyopathy;Cardiac muscle contraction;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Vascular smooth muscle contraction;Regulation of actin cytoskeleton;K12478//Phagosome;Endocytosis;Tuberculosis
9721,89,0,0,0,7,0,23,0,51,0,0,0,GPRIN2;G protein regulated inducer of neurite outgrowth 2,-,-,GO:0005515//protein binding,-
9722,0,0,0,0,0,17,57,39,14,183,7,0,NOS1AP;nitric oxide synthase 1 (neuronal) adaptor protein,-,GO:0042981//regulation of apoptotic process;GO:0050999//regulation of nitric-oxide synthase activity;GO:0045428//regulation of nitric oxide biosynthetic process,GO:0050998//nitric-oxide synthase binding,K12474//Endocytosis
9723,2,0,0,0,16,0,0,0,29,0,0,0,"SEMA3E;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E",GO:0016020//membrane;GO:0005615//extracellular space;GO:0005576//extracellular region,GO:0001569//patterning of blood vessels;GO:2000249//regulation of actin cytoskeleton reorganization;GO:0016525//negative regulation of angiogenesis;GO:0002040//sprouting angiogenesis;GO:0001953//negative regulation of cell-matrix adhesion;GO:0050808//synapse organization;GO:0007411//axon guidance;GO:0071526//semaphorin-plexin signaling pathway;GO:0008360//regulation of cell shape,GO:0005515//protein binding;GO:0004872//receptor activity;GO:0030215//semaphorin receptor binding,K06840//Axon guidance
9724,0,0,0,0,1,17,0,0,0,0,0,0,"UTP14C;UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)",GO:0005730//nucleolus;GO:0032040//small-subunit processome,GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis;GO:0030154//cell differentiation;GO:0007126//meiotic nuclear division;GO:0006364//rRNA processing,-,K14567//Ribosome biogenesis in eukaryotes
9725,0,0,0,0,0,18,57,42,39,0,0,0,TMEM63A;transmembrane protein 63A,GO:0070062//extracellular vesicular exosome;GO:0016021//integral component of membrane;GO:0005765//lysosomal membrane,GO:0006811//ion transport,GO:0000166//nucleotide binding,K00728//Other types of O-glycan biosynthesis
9726,0,0,0,0,1,2,0,0,19,4,1,591,ZNF646;zinc finger protein 646,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0003677//DNA binding,-
9727,0,0,0,6,29,40,27,37,47,13,15,0,RAB11FIP3;RAB11 family interacting protein 3 (class II),GO:0005813//centrosome;GO:0032154//cleavage furrow;GO:0005768//endosome;GO:0005815//microtubule organizing center;GO:0055037//recycling endosome;GO:0005634//nucleus;GO:0043231//intracellular membrane-bounded organelle;GO:0030496//midbody;GO:0005730//nucleolus;GO:0055038//recycling endosome membrane;GO:0045171//intercellular bridge,GO:0000910//cytokinesis;GO:0032456//endocytic recycling;GO:0016192//vesicle-mediated transport,GO:0017137//Rab GTPase binding;GO:0030306//ADP-ribosylation factor binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0005509//calcium ion binding,K12485//Endocytosis
9728,0,16,2,128,326,0,0,28,0,0,23,0,SECISBP2L;SECIS binding protein 2-like,-,-,GO:0044822//poly(A) RNA binding,-
9729,0,0,0,0,0,2,0,0,0,0,0,0,KIAA0408;KIAA0408,-,-,GO:0005515//protein binding,K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Gastric acid secretion;Proximal tubule bicarbonate reclamation;Bile secretion;Aldosterone-regulated sodium reabsorption;Endocrine and other factor-regulated calcium reabsorption;Mineral absorption;Pancreatic secretion;Cardiac muscle contraction;Protein digestion and absorption;Salivary secretion;Carbohydrate digestion and absorption;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways
973,0,0,0,0,0,0,0,0,12,0,0,0,"CD79A;CD79a molecule, immunoglobulin-associated alpha",GO:0019815//B cell receptor complex;GO:0005886//plasma membrane;GO:0009897//external side of plasma membrane;GO:0005771//multivesicular body;GO:0016021//integral component of membrane;GO:0045121//membrane raft,GO:0050853//B cell receptor signaling pathway;GO:0042113//B cell activation;GO:0042100//B cell proliferation;GO:0030183//B cell differentiation,GO:0004888//transmembrane signaling receptor activity,K06506//Primary immunodeficiency;B cell receptor signaling pathway
9730,56,546,208,334,563,36,4,241,41,0,672,0,VPRBP;Vpr (HIV-1) binding protein,GO:0008180//COP9 signalosome;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0016032//viral process;GO:0030183//B cell differentiation;GO:0035212//cell competition in a multicellular organism;GO:0033151//V(D)J recombination;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:1990245//histone H2A-T120 phosphorylation;GO:0016567//protein ubiquitination;GO:0006351//transcription, DNA-templated",GO:0005524//ATP binding;GO:1990244//histone kinase activity (H2A-T120 specific);GO:0005515//protein binding,-
9731,0,1,0,7,28,0,0,0,43,0,0,0,CEP104;centrosomal protein 104kDa,GO:0005814//centriole,-,GO:0016595//glutamate binding;GO:0016596//thienylcyclohexylpiperidine binding;GO:0016594//glycine binding,K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
9732,9,0,1,24,21,9,25,0,44,5,18,0,DOCK4;dedicator of cytokinesis 4,GO:0016020//membrane;GO:0005829//cytosol;GO:0032421//stereocilium bundle;GO:0012505//endomembrane system;GO:0032420//stereocilium,GO:0007264//small GTPase mediated signal transduction;GO:0032855//positive regulation of Rac GTPase activity;GO:0060326//cell chemotaxis,GO:0030971//receptor tyrosine kinase binding;GO:0048365//Rac GTPase binding;GO:0005085//guanyl-nucleotide exchange factor activity;GO:0030165//PDZ domain binding;GO:0005515//protein binding;GO:0017124//SH3 domain binding;GO:0030675//Rac GTPase activator activity,-
9733,0,31,40,16,11,1,0,52,10,0,0,0,SART3;squamous cell carcinoma antigen recognized by T cells 3,GO:0005737//cytoplasm;GO:0016607//nuclear speck,GO:0048872//homeostasis of number of cells;GO:0010468//regulation of gene expression;GO:0071425//hematopoietic stem cell proliferation;GO:0006396//RNA processing;GO:0000902//cell morphogenesis,GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding,K11294//Pathogenic Escherichia coli infection
9734,0,22,0,0,28,9,59,0,163,0,1,0,HDAC9;histone deacetylase 9,GO:0005634//nucleus;GO:0035097//histone methyltransferase complex;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005667//transcription factor complex;GO:0000118//histone deacetylase complex,"GO:0051153//regulation of striated muscle cell differentiation;GO:0007219//Notch signaling pathway;GO:0042113//B cell activation;GO:0090050//positive regulation of cell migration involved in sprouting angiogenesis;GO:0048742//regulation of skeletal muscle fiber development;GO:0006954//inflammatory response;GO:0030183//B cell differentiation;GO:0070933//histone H4 deacetylation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0016575//histone deacetylation;GO:0070932//histone H3 deacetylation;GO:0007507//heart development;GO:0034983//peptidyl-lysine deacetylation;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0032869//cellular response to insulin stimulus",GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008134//transcription factor binding;GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0005080//protein kinase C binding;GO:0004407//histone deacetylase activity;GO:0070491//repressing transcription factor binding;GO:0042826//histone deacetylase binding;GO:0033558//protein deacetylase activity;GO:0003714//transcription corepressor activity,K11409//Alcoholism
9735,0,0,0,4,14,16,71,0,57,101,11,299,KNTC1;kinetochore associated 1,GO:0000922//spindle pole;GO:0005634//nucleus;GO:0005829//cytosol;GO:0015629//actin cytoskeleton;GO:0005737//cytoplasm;GO:0000777//condensed chromosome kinetochore;GO:0005828//kinetochore microtubule;GO:0005886//plasma membrane,GO:0006461//protein complex assembly;GO:0007093//mitotic cell cycle checkpoint;GO:0007067//mitotic nuclear division;GO:0007096//regulation of exit from mitosis;GO:0000278//mitotic cell cycle,GO:0005515//protein binding,-
9736,0,35,2,115,379,44,103,63,145,1,8,0,USP34;ubiquitin specific peptidase 34,-,GO:0016579//protein deubiquitination;GO:0016055//Wnt signaling pathway;GO:0090263//positive regulation of canonical Wnt signaling pathway;GO:0071108//protein K48-linked deubiquitination;GO:0006511//ubiquitin-dependent protein catabolic process,GO:0004843//ubiquitin-specific protease activity;GO:0004197//cysteine-type endopeptidase activity;GO:0005515//protein binding;GO:0004221//ubiquitin thiolesterase activity,-
9737,0,25,1,4,98,0,0,27,51,0,0,0,GPRASP1;G protein-coupled receptor associated sorting protein 1,GO:0005737//cytoplasm,GO:1990172//G-protein coupled receptor catabolic process;GO:0008333//endosome to lysosome transport,GO:0005515//protein binding,-
9738,0,0,0,59,21,5,12,0,14,0,0,0,CCP110;centriolar coiled coil protein 110kDa,GO:0005814//centriole;GO:0005829//cytosol;GO:0005813//centrosome;GO:0043234//protein complex,GO:0051298//centrosome duplication;GO:0032465//regulation of cytokinesis;GO:0000086//G2/M transition of mitotic cell cycle;GO:0007099//centriole replication;GO:0000278//mitotic cell cycle;GO:0030030//cell projection organization,GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;K09057//Circadian rhythm - fly;K11447//Transcriptional misregulation in cancer;K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Salivary secretion;Protein digestion and absorption;Cardiac muscle contraction;Carbohydrate digestion and absorption;Aldosterone-regulated sodium reabsorption;Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption
9739,0,1,12,0,6,32,0,55,46,0,35,0,SETD1A;SET domain containing 1A,GO:0005694//chromosome;GO:0005730//nucleolus;GO:0016607//nuclear speck;GO:0005634//nucleus;GO:0035097//histone methyltransferase complex;GO:0048188//Set1C/COMPASS complex,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation",GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding;GO:0042800//histone methyltransferase activity (H3-K4 specific),K11422//Lysine degradation
974,0,0,0,0,0,0,3,0,26,0,0,0,"CD79B;CD79b molecule, immunoglobulin-associated beta",GO:0070062//extracellular vesicular exosome;GO:0009897//external side of plasma membrane;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0019815//B cell receptor complex;GO:0005730//nucleolus;GO:0005634//nucleus;GO:0005887//integral component of plasma membrane,GO:0006955//immune response;GO:0050853//B cell receptor signaling pathway;GO:0007165//signal transduction,GO:0004888//transmembrane signaling receptor activity,K06507//B cell receptor signaling pathway
9741,0,0,0,7,21,7,0,54,0,0,7,0,LAPTM4A;lysosomal protein transmembrane 4 alpha,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0006810//transport,-,K12387//Lysosome
9742,0,0,1,16,2,42,38,0,48,0,0,1,IFT140;intraflagellar transport 140,GO:0036064//ciliary basal body;GO:0030991//intraciliary transport particle A;GO:0005930//axoneme;GO:0005813//centrosome;GO:0032391//photoreceptor connecting cilium,GO:0060041//retina development in camera-type eye;GO:0061512//protein localization to cilium;GO:0072001//renal system development;GO:1902017//regulation of cilium assembly;GO:0042384//cilium assembly;GO:0035721//intraciliary retrograde transport;GO:0048705//skeletal system morphogenesis,-,-
9743,0,0,1,53,165,22,18,0,51,0,0,0,ARHGAP32;Rho GTPase activating protein 32,GO:0000139//Golgi membrane;GO:0045211//postsynaptic membrane;GO:0010008//endosome membrane;GO:0030054//cell junction;GO:0014069//postsynaptic density;GO:0005938//cell cortex;GO:0043197//dendritic spine;GO:0015629//actin cytoskeleton;GO:0005829//cytosol;GO:0005789//endoplasmic reticulum membrane,GO:0043547//positive regulation of GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction,GO:0005515//protein binding;GO:0035091//phosphatidylinositol binding;GO:0005096//GTPase activator activity,K04450//Epstein-Barr virus infection;MAPK signaling pathway;Amphetamine addiction;Alcoholism;Influenza A;Cocaine addiction;Dopaminergic synapse;HTLV-I infection;K08878//Pathways in cancer;Chronic myeloid leukemia
9744,0,13,51,38,62,0,0,1,25,0,123,18,"ACAP1;ArfGAP with coiled-coil, ankyrin repeat and PH domains 1",GO:0016020//membrane;GO:0055038//recycling endosome membrane,GO:0043547//positive regulation of GTPase activity;GO:0015031//protein transport;GO:0032312//regulation of ARF GTPase activity,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity,K12489//Endocytosis
9745,93,0,0,0,0,0,0,20,18,0,0,0,ZNF536;zinc finger protein 536,GO:0005634//nucleus,"GO:0048387//negative regulation of retinoic acid receptor signaling pathway;GO:0006355//regulation of transcription, DNA-templated;GO:0045665//negative regulation of neuron differentiation;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0044323//retinoic acid-responsive element binding,-
9746,18,0,31,0,0,6,34,0,49,296,0,0,CLSTN3;calsyntenin 3,GO:0070062//extracellular vesicular exosome;GO:0045211//postsynaptic membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005789//endoplasmic reticulum membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
9747,1,25,2,54,158,21,26,59,38,0,0,0,"FAM115A;family with sequence similarity 115, member A",-,-,-,-
9748,152,36,2,88,287,0,54,70,76,94,7,0,SLK;STE20-like kinase,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0046777//protein autophosphorylation;GO:0006915//apoptotic process,GO:0004674//protein serine/threonine kinase activity;GO:0042803//protein homodimerization activity;GO:0042802//identical protein binding;GO:0005524//ATP binding,K08836//Oocyte meiosis
9749,0,83,44,63,305,67,13,0,77,169,17,0,PHACTR2;phosphatase and actin regulator 2,-,GO:0043086//negative regulation of catalytic activity,GO:0004864//protein phosphatase inhibitor activity;GO:0003779//actin binding;GO:0005515//protein binding,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;K11447//Transcriptional misregulation in cancer
9750,108,0,0,6,0,9,39,0,35,0,24,0,"FAM65B;family with sequence similarity 65, member B",GO:0005856//cytoskeleton;GO:0005739//mitochondrion;GO:0030175//filopodium,GO:0007517//muscle organ development;GO:0030154//cell differentiation,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction;K05767//Regulation of actin cytoskeleton;Adherens junction
9751,0,0,0,0,1,42,0,0,38,0,2,0,SNPH;syntaphilin,GO:0042734//presynaptic membrane;GO:0005881//cytoplasmic microtubule;GO:0030054//cell junction;GO:0031966//mitochondrial membrane;GO:0016021//integral component of membrane;GO:0043005//neuron projection;GO:0043025//neuronal cell body,GO:0030182//neuron differentiation;GO:0016081//synaptic vesicle docking involved in exocytosis;GO:0007269//neurotransmitter secretion;GO:0007420//brain development,GO:0017075//syntaxin-1 binding,-
9752,4,0,0,0,0,0,30,0,16,0,12,0,PCDHA9;protocadherin alpha 9,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules,GO:0005509//calcium ion binding,-
9753,0,0,0,18,32,20,0,0,7,0,0,0,ZSCAN12;zinc finger and SCAN domain containing 12,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
9754,0,0,0,0,0,47,42,66,57,0,0,0,STARD8;StAR-related lipid transfer (START) domain containing 8,GO:0005829//cytosol;GO:0005925//focal adhesion,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0008289//lipid binding;GO:0005096//GTPase activator activity,K08878//Pathways in cancer;Chronic myeloid leukemia;K12490//Endocytosis;K07526//Axon guidance
9755,0,0,0,0,0,0,38,0,10,3,4,0,TBKBP1;TBK1 binding protein 1,-,GO:0045087//innate immune response,GO:0005515//protein binding,K12652//RIG-I-like receptor signaling pathway
9757,174,0,0,0,0,0,52,0,52,34,19,0,KMT2B;lysine (K)-specific methyltransferase 2B,GO:0035097//histone methyltransferase complex;GO:0005634//nucleus,"GO:0051569//regulation of histone H3-K4 methylation;GO:0048096//chromatin-mediated maintenance of transcription;GO:0009994//oocyte differentiation;GO:0030728//ovulation;GO:0001541//ovarian follicle development;GO:0006351//transcription, DNA-templated;GO:0051568//histone H3-K4 methylation;GO:0080182//histone H3-K4 trimethylation;GO:0016458//gene silencing",GO:0042800//histone methyltransferase activity (H3-K4 specific);GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,K14959//Lysine degradation
9758,0,0,0,0,0,58,87,47,110,0,0,0,FRMPD4;FERM and PDZ domain containing 4,GO:0005856//cytoskeleton;GO:0043197//dendritic spine,GO:0051835//positive regulation of synapse structural plasticity,"GO:0005515//protein binding;GO:0005546//phosphatidylinositol-4,5-bisphosphate binding",K00948//Microbial metabolism in diverse environments;Oxidative phosphorylation;Pentose phosphate pathway;Metabolic pathways;Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;K05725//Small cell lung cancer;Leukocyte transendothelial migration;Transcriptional misregulation in cancer;Bacterial invasion of epithelial cells;Chemokine signaling pathway;Pathways in cancer;Axon guidance;Amoebiasis;Focal adhesion;VEGF signaling pathway;ErbB signaling pathway;Regulation of actin cytoskeleton
9759,146,0,0,5,1,3,0,0,48,0,27,1,HDAC4;histone deacetylase 4,GO:0005829//cytosol;GO:0031672//A band;GO:0005634//nucleus;GO:0031594//neuromuscular junction;GO:0000118//histone deacetylase complex;GO:0017053//transcriptional repressor complex;GO:0042641//actomyosin;GO:0005737//cytoplasm;GO:0030018//Z disc,"GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0010882//regulation of cardiac muscle contraction by calcium ion signaling;GO:0014894//response to denervation involved in regulation of muscle adaptation;GO:0040029//regulation of gene expression, epigenetic;GO:0070932//histone H3 deacetylation;GO:0045893//positive regulation of transcription, DNA-templated;GO:0043433//negative regulation of sequence-specific DNA binding transcription factor activity;GO:0034983//peptidyl-lysine deacetylation;GO:0042493//response to drug;GO:0007399//nervous system development;GO:0045668//negative regulation of osteoblast differentiation;GO:0045892//negative regulation of transcription, DNA-templated;GO:0042113//B cell activation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006954//inflammatory response;GO:0048742//regulation of skeletal muscle fiber development;GO:0030183//B cell differentiation;GO:0043393//regulation of protein binding;GO:0070555//response to interleukin-1;GO:0033235//positive regulation of protein sumoylation;GO:0008285//negative regulation of cell proliferation;GO:0006351//transcription, DNA-templated;GO:0010832//negative regulation of myotube differentiation;GO:0008284//positive regulation of cell proliferation;GO:0002076//osteoblast development;GO:0045820//negative regulation of glycolytic process;GO:0001501//skeletal system development;GO:0006338//chromatin remodeling;GO:0016575//histone deacetylation;GO:0070933//histone H4 deacetylation;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity;GO:0014898//cardiac muscle hypertrophy in response to stress",GO:0044212//transcription regulatory region DNA binding;GO:0046970//NAD-dependent histone deacetylase activity (H4-K16 specific);GO:0097372//NAD-dependent histone deacetylase activity (H3-K18 specific);GO:0042826//histone deacetylase binding;GO:0043565//sequence-specific DNA binding;GO:0033613//activating transcription factor binding;GO:0046969//NAD-dependent histone deacetylase activity (H3-K9 specific);GO:0005515//protein binding;GO:0032041//NAD-dependent histone deacetylase activity (H3-K14 specific);GO:0008270//zinc ion binding;GO:0008134//transcription factor binding;GO:0033558//protein deacetylase activity;GO:0003714//transcription corepressor activity;GO:0001047//core promoter binding;GO:0019901//protein kinase binding;GO:0070491//repressing transcription factor binding;GO:0030955//potassium ion binding;GO:0004407//histone deacetylase activity,K11406//Epstein-Barr virus infection;Alcoholism
976,68,0,0,1,0,19,0,0,56,0,14,0,CD97;CD97 molecule,GO:0005925//focal adhesion;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0016020//membrane;GO:0005887//integral component of plasma membrane,GO:0007218//neuropeptide signaling pathway;GO:0007166//cell surface receptor signaling pathway;GO:0006955//immune response;GO:0007186//G-protein coupled receptor signaling pathway;GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0007267//cell-cell signaling;GO:0006954//inflammatory response,GO:0005509//calcium ion binding;GO:0004888//transmembrane signaling receptor activity;GO:0005515//protein binding;GO:0004930//G-protein coupled receptor activity,-
9760,0,0,0,0,0,18,13,0,33,0,5,0,TOX;thymocyte selection-associated high mobility group box,GO:0005634//nucleus,-,GO:0003677//DNA binding,-
9761,120,17,0,6,99,10,0,0,54,0,11,0,MLEC;malectin,GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006457//protein folding;GO:0043687//post-translational protein modification;GO:0044267//cellular protein metabolic process;GO:0018279//protein N-linked glycosylation via asparagine,GO:0030246//carbohydrate binding;GO:0019899//enzyme binding,-
9762,0,10,0,5,3,0,35,0,58,0,3,0,"LZTS3;leucine zipper, putative tumor suppressor family member 3",GO:0014069//postsynaptic density;GO:0005737//cytoplasm;GO:0045211//postsynaptic membrane;GO:0030054//cell junction,-,-,-
9764,0,0,0,10,1,23,32,96,60,0,1,1,KIAA0513;KIAA0513,GO:0005737//cytoplasm,-,-,K11447//Transcriptional misregulation in cancer;K00939//Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;Metabolic pathways;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways
9765,0,112,354,295,326,20,107,0,84,2,181,0,"ZFYVE16;zinc finger, FYVE domain containing 16",GO:0005737//cytoplasm;GO:0031901//early endosome membrane;GO:0043231//intracellular membrane-bounded organelle;GO:0005769//early endosome,GO:0016050//vesicle organization;GO:0030509//BMP signaling pathway;GO:0006622//protein targeting to lysosome;GO:0016197//endosomal transport;GO:0007165//signal transduction;GO:0030100//regulation of endocytosis,"GO:0005515//protein binding;GO:0046872//metal ion binding;GO:0005545//1-phosphatidylinositol binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008565//protein transporter activity",K04679//TGF-beta signaling pathway;Endocytosis
9766,0,0,1,10,0,14,0,0,41,0,0,0,KIAA0247;KIAA0247,GO:0016021//integral component of membrane,-,-,-
9767,0,1,0,20,41,21,0,58,43,0,0,0,JADE3;jade family PHD finger 3,GO:0000123//histone acetyltransferase complex,GO:0043966//histone H3 acetylation;GO:0043984//histone H4-K16 acetylation;GO:0043983//histone H4-K12 acetylation;GO:0043981//histone H4-K5 acetylation;GO:0043982//histone H4-K8 acetylation,GO:0008270//zinc ion binding,-
9768,1,0,0,0,0,0,1,0,15,1,4,0,KIAA0101;KIAA0101,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0019985//translesion synthesis;GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0051297//centrosome organization;GO:0009411//response to UV;GO:0006974//cellular response to DNA damage stimulus,GO:0005515//protein binding;GO:0003682//chromatin binding,K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K00797//Arginine and proline metabolism;Glutathione metabolism;Cysteine and methionine metabolism;Ribosome;beta-Alanine metabolism;Metabolic pathways;K11447//Transcriptional misregulation in cancer
977,1,0,0,0,0,0,0,63,7,0,0,352,CD151;CD151 molecule (Raph blood group),GO:0005829//cytosol;GO:0016020//membrane;GO:0005925//focal adhesion;GO:0005886//plasma membrane;GO:0005887//integral component of plasma membrane,GO:0016477//cell migration;GO:0042098//T cell proliferation;GO:0031581//hemidesmosome assembly;GO:0030198//extracellular matrix organization;GO:0007155//cell adhesion;GO:0034329//cell junction assembly,GO:0005178//integrin binding;GO:0005515//protein binding,-
9770,63,0,0,0,18,1,0,2,19,4,1,0,RASSF2;Ras association (RalGDS/AF-6) domain family member 2,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0045667//regulation of osteoblast differentiation;GO:0046849//bone remodeling;GO:0048872//homeostasis of number of cells;GO:0001501//skeletal system development;GO:0007049//cell cycle;GO:0001503//ossification;GO:0045670//regulation of osteoclast differentiation;GO:1901223//negative regulation of NIK/NF-kappaB signaling,GO:0005515//protein binding,-
9771,0,0,0,0,0,10,28,63,48,1,6,0,RAPGEF5;Rap guanine nucleotide exchange factor (GEF) 5,GO:0005634//nucleus,GO:0032320//positive regulation of Ras GTPase activity;GO:0007264//small GTPase mediated signal transduction;GO:0007399//nervous system development;GO:0032854//positive regulation of Rap GTPase activity,GO:0030742//GTP-dependent protein binding;GO:0005088//Ras guanyl-nucleotide exchange factor activity;GO:0017034//Rap guanyl-nucleotide exchange factor activity,-
9772,0,17,0,10,23,0,15,0,72,0,20,0,KIAA0195;KIAA0195,GO:0005730//nucleolus;GO:0016021//integral component of membrane;GO:0005634//nucleus,-,-,-
9774,0,1,0,0,22,0,0,0,0,0,0,0,BCLAF1;BCL2-associated transcription factor 1,GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043620//regulation of DNA-templated transcription in response to stress;GO:2001244//positive regulation of intrinsic apoptotic signaling pathway;GO:2000144//positive regulation of DNA-templated transcription, initiation;GO:2001022//positive regulation of response to DNA damage stimulus;GO:0043065//positive regulation of apoptotic process",GO:0003677//DNA binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding,-
9775,0,1,0,9,22,0,0,0,47,0,0,0,EIF4A3;eukaryotic translation initiation factor 4A3,GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome;GO:0005737//cytoplasm;GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0005634//nucleus,"GO:0048701//embryonic cranial skeleton morphogenesis;GO:0006364//rRNA processing;GO:0051028//mRNA transport;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0045727//positive regulation of translation;GO:0016071//mRNA metabolic process;GO:0017148//negative regulation of translation;GO:0016070//RNA metabolic process;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006200//ATP catabolic process;GO:0000398//mRNA splicing, via spliceosome;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0019221//cytokine-mediated signaling pathway;GO:0010467//gene expression",GO:0003729//mRNA binding;GO:0004004//ATP-dependent RNA helicase activity;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008143//poly(A) binding;GO:0005524//ATP binding,K13025//Spliceosome;RNA transport;mRNA surveillance pathway
9776,0,1,0,24,33,7,0,0,49,0,5,0,ATG13;autophagy related 13,GO:0070969//ULK1-ATG13-FIP200 complex;GO:0000407//pre-autophagosomal structure;GO:0005829//cytosol;GO:0034273//ATG1/UKL1 signaling complex,GO:0000045//autophagic vacuole assembly,GO:0019901//protein kinase binding;GO:0005515//protein binding,-
9777,7,0,0,9,27,35,2,0,40,0,0,0,TM9SF4;transmembrane 9 superfamily protein member 4,GO:0016021//integral component of membrane,-,-,-
9778,0,36,0,44,123,0,0,0,60,0,5,0,KIAA0232;KIAA0232,-,-,GO:0005524//ATP binding,-
9779,52,1,2,75,75,0,1,0,74,0,0,0,"TBC1D5;TBC1 domain family, member 5",GO:0030904//retromer complex,GO:1902017//regulation of cilium assembly;GO:0032851//positive regulation of Rab GTPase activity,GO:0005515//protein binding;GO:0005097//Rab GTPase activator activity,K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
978,0,0,0,0,0,0,0,0,4,0,0,0,CDA;cytidine deaminase,GO:0005576//extracellular region;GO:0005829//cytosol,GO:0044281//small molecule metabolic process;GO:0009972//cytidine deamination;GO:0051289//protein homotetramerization;GO:0030308//negative regulation of cell growth;GO:0043097//pyrimidine nucleoside salvage;GO:0007166//cell surface receptor signaling pathway;GO:0006206//pyrimidine nucleobase metabolic process;GO:0019858//cytosine metabolic process;GO:0045980//negative regulation of nucleotide metabolic process,GO:0004126//cytidine deaminase activity;GO:0001882//nucleoside binding;GO:0042803//protein homodimerization activity;GO:0008270//zinc ion binding,K01489//Metabolic pathways;Pyrimidine metabolism;Drug metabolism - other enzymes
9780,153,0,2,18,12,36,54,0,99,207,23,266,PIEZO1;piezo-type mechanosensitive ion channel component 1,GO:0005789//endoplasmic reticulum membrane;GO:0005886//plasma membrane;GO:0033116//endoplasmic reticulum-Golgi intermediate compartment membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum,GO:0033625//positive regulation of integrin activation;GO:0042391//regulation of membrane potential;GO:0050982//detection of mechanical stimulus;GO:0033634//positive regulation of cell-cell adhesion mediated by integrin;GO:0006812//cation transport,GO:0008381//mechanically-gated ion channel activity;GO:0005261//cation channel activity,-
9781,0,1,0,7,43,26,0,0,22,0,0,0,RNF144A;ring finger protein 144A,GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0016567//protein ubiquitination,GO:0016874//ligase activity;GO:0008270//zinc ion binding,-
9782,0,73,0,97,383,23,0,0,9,0,7,0,MATR3;matrin 3,GO:0005637//nuclear inner membrane;GO:0005730//nucleolus;GO:0016020//membrane;GO:0005634//nucleus;GO:0016363//nuclear matrix,GO:0008219//cell death,GO:0008270//zinc ion binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0000166//nucleotide binding;GO:0005198//structural molecule activity,-
9783,1,25,0,0,6,11,0,55,6,0,0,0,RIMS3;regulating synaptic membrane exocytosis 3,GO:0030054//cell junction;GO:0048786//presynaptic active zone,GO:0006836//neurotransmitter transport;GO:0042391//regulation of membrane potential;GO:0006887//exocytosis,GO:0044325//ion channel binding,-
9784,86,56,1,22,92,0,13,4,6,0,14,0,SNX17;sorting nexin 17,GO:0043231//intracellular membrane-bounded organelle;GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0030659//cytoplasmic vesicle membrane;GO:0010008//endosome membrane;GO:0016020//membrane;GO:0005794//Golgi apparatus;GO:0005768//endosome;GO:0005769//early endosome;GO:0043234//protein complex;GO:0005737//cytoplasm,GO:0007165//signal transduction;GO:0016197//endosomal transport;GO:0006886//intracellular protein transport;GO:0006707//cholesterol catabolic process;GO:0030100//regulation of endocytosis;GO:0006898//receptor-mediated endocytosis,GO:0035091//phosphatidylinositol binding;GO:0005515//protein binding;GO:0050750//low-density lipoprotein particle receptor binding;GO:0008022//protein C-terminus binding;GO:0005102//receptor binding,-
9785,0,28,0,4,8,9,1,0,46,10,11,0,DHX38;DEAH (Asp-Glu-Ala-His) box polypeptide 38,GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0016020//membrane;GO:0071013//catalytic step 2 spliceosome,"GO:0006366//transcription from RNA polymerase II promoter;GO:0000398//mRNA splicing, via spliceosome;GO:0006369//termination of RNA polymerase II transcription;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0006200//ATP catabolic process",GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding;GO:0005515//protein binding;GO:0008026//ATP-dependent helicase activity,K12815//Spliceosome
9786,0,1,0,15,16,46,0,136,84,0,32,0,KIAA0586;KIAA0586,GO:0036064//ciliary basal body;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0042384//cilium assembly;GO:0070201//regulation of establishment of protein localization;GO:0060271//cilium morphogenesis;GO:0007224//smoothened signaling pathway,-,-
9787,12,0,0,0,0,16,0,0,14,0,3,0,"DLGAP5;discs, large (Drosophila) homolog-associated protein 5",GO:0031616//spindle pole centrosome;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0007267//cell-cell signaling;GO:0045842//positive regulation of mitotic metaphase/anaphase transition;GO:0016311//dephosphorylation;GO:0008283//cell proliferation;GO:0007079//mitotic chromosome movement towards spindle pole,GO:0004721//phosphoprotein phosphatase activity;GO:0005515//protein binding,K15008//Glutamatergic synapse
9788,0,2,0,12,27,0,0,1,15,226,0,0,MTSS1;metastasis suppressor 1,GO:0005737//cytoplasm;GO:0005912//adherens junction;GO:0030139//endocytic vesicle;GO:0001726//ruffle;GO:0015629//actin cytoskeleton,GO:0001701//in utero embryonic development;GO:2001013//epithelial cell proliferation involved in renal tubule morphogenesis;GO:0071498//cellular response to fluid shear stress;GO:0030041//actin filament polymerization;GO:0030036//actin cytoskeleton organization;GO:0072160//nephron tubule epithelial cell differentiation;GO:0072102//glomerulus morphogenesis;GO:0032233//positive regulation of actin filament bundle assembly;GO:0061333//renal tubule morphogenesis;GO:0046847//filopodium assembly;GO:0030035//microspike assembly;GO:0010960//magnesium ion homeostasis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0034334//adherens junction maintenance;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0006928//cellular component movement;GO:0007155//cell adhesion;GO:0030282//bone mineralization,GO:0005102//receptor binding;GO:0003785//actin monomer binding;GO:0042802//identical protein binding;GO:0005515//protein binding;GO:0008093//cytoskeletal adaptor activity;GO:0017124//SH3 domain binding;GO:0051015//actin filament binding,K05627//Regulation of actin cytoskeleton;Adherens junction
9789,0,0,0,10,9,0,0,0,17,117,0,0,SPCS2;signal peptidase complex subunit 2 homolog (S. cerevisiae),GO:0016021//integral component of membrane;GO:0005789//endoplasmic reticulum membrane;GO:0005787//signal peptidase complex,GO:0044267//cellular protein metabolic process;GO:0006508//proteolysis;GO:0010467//gene expression;GO:0006614//SRP-dependent cotranslational protein targeting to membrane;GO:0006412//translation;GO:0006465//signal peptide processing;GO:0050796//regulation of insulin secretion,GO:0008233//peptidase activity,K12947//Protein export
9790,1,0,0,1,20,0,28,52,83,0,13,0,BMS1;BMS1 ribosome biogenesis factor,GO:0005634//nucleus;GO:0005730//nucleolus,GO:0042255//ribosome assembly,GO:0005524//ATP binding;GO:0044822//poly(A) RNA binding,K14569//Ribosome biogenesis in eukaryotes
9791,0,0,0,1,9,13,4,0,3,0,0,0,PTDSS1;phosphatidylserine synthase 1,GO:0016021//integral component of membrane;GO:0016020//membrane;GO:0005789//endoplasmic reticulum membrane,GO:0006659//phosphatidylserine biosynthetic process;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process,GO:0016740//transferase activity,K08729//Metabolic pathways;Glycerophospholipid metabolism
9792,0,0,0,7,32,0,42,0,48,185,4,0,SERTAD2;SERTA domain containing 2,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030308//negative regulation of cell growth",GO:0003713//transcription coactivator activity,-
9793,89,33,3,20,113,9,30,44,69,285,0,0,CKAP5;cytoskeleton associated protein 5,GO:0005829//cytosol;GO:0000922//spindle pole;GO:0015630//microtubule cytoskeleton;GO:0035371//microtubule plus-end;GO:0000930//gamma-tubulin complex;GO:0016020//membrane;GO:0043234//protein complex;GO:0005813//centrosome,GO:0030951//establishment or maintenance of microtubule cytoskeleton polarity;GO:0051297//centrosome organization;GO:0007051//spindle organization;GO:0007067//mitotic nuclear division;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0050658//RNA transport,GO:0005515//protein binding,-
9794,0,0,1,0,1,21,80,0,56,0,2,0,MAML1;mastermind-like 1 (Drosophila),GO:0002193//MAML1-RBP-Jkappa- ICN1 complex;GO:0016607//nuclear speck;GO:0043231//intracellular membrane-bounded organelle;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus,GO:0006468//protein phosphorylation;GO:0010467//gene expression;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010831//positive regulation of myotube differentiation;GO:0007219//Notch signaling pathway;GO:0003162//atrioventricular node development;GO:0060928//atrioventricular node cell development;GO:0045445//myoblast differentiation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter,GO:0003713//transcription coactivator activity;GO:0019901//protein kinase binding;GO:0042605//peptide antigen binding;GO:0005515//protein binding,K06061//Notch signaling pathway
9796,1,0,37,0,0,24,0,0,51,0,7,1,PHYHIP;phytanoyl-CoA 2-hydroxylase interacting protein,-,-,-,-
9797,0,20,1,35,16,33,0,124,49,0,0,0,TATDN2;TatD DNase domain containing 2,GO:0043229//intracellular organelle;GO:0005654//nucleoplasm,"GO:0000737//DNA catabolic process, endonucleolytic;GO:0006987//activation of signaling protein activity involved in unfolded protein response;GO:0006308//DNA catabolic process;GO:0044267//cellular protein metabolic process;GO:0030968//endoplasmic reticulum unfolded protein response","GO:0016888//endodeoxyribonuclease activity, producing 5'-phosphomonoesters;GO:0046872//metal ion binding;GO:0004536//deoxyribonuclease activity",-
9798,2,24,23,27,41,13,0,0,8,267,8,0,IST1;increased sodium tolerance 1 homolog (yeast),GO:0090543//Flemming body;GO:0070062//extracellular vesicular exosome;GO:0030496//midbody;GO:0005829//cytosol;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005813//centrosome;GO:0005793//endoplasmic reticulum-Golgi intermediate compartment,GO:0046745//viral capsid secondary envelopment;GO:0045862//positive regulation of proteolysis;GO:0045184//establishment of protein localization;GO:0008104//protein localization;GO:0000910//cytokinesis;GO:0048672//positive regulation of collateral sprouting;GO:0051301//cell division;GO:0019076//viral release from host cell;GO:0009838//abscission,GO:0005515//protein binding;GO:0090541//MIT domain binding;GO:0019904//protein domain specific binding;GO:0032403//protein complex binding,-
98,0,20,0,10,32,20,16,0,1,0,3,0,"ACYP2;acylphosphatase 2, muscle type",GO:0005739//mitochondrion,GO:0006796//phosphate-containing compound metabolic process,GO:0003998//acylphosphatase activity,K01512//Microbial metabolism in diverse environments;Pyruvate metabolism;Metabolic pathways;Aminobenzoate degradation;Pyrimidine metabolism
9801,0,1,12,58,79,26,0,0,14,0,5,1,MRPL19;mitochondrial ribosomal protein L19,GO:0005840//ribosome;GO:0005739//mitochondrion;GO:0031965//nuclear membrane;GO:0005634//nucleus,GO:0006412//translation,GO:0003735//structural constituent of ribosome,-
9802,0,101,1,84,343,0,0,39,0,0,72,0,DAZAP2;DAZ associated protein 2,GO:0005634//nucleus;GO:0005737//cytoplasm,-,GO:0005515//protein binding;GO:0050699//WW domain binding,-
9804,0,18,4,93,392,1,31,79,0,0,0,0,TOMM20;translocase of outer mitochondrial membrane 20 homolog (yeast),GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005742//mitochondrial outer membrane translocase complex,GO:0044267//cellular protein metabolic process;GO:0071806//protein transmembrane transport;GO:0006626//protein targeting to mitochondrion,GO:0051082//unfolded protein binding;GO:0015450//P-P-bond-hydrolysis-driven protein transmembrane transporter activity;GO:0005515//protein binding,-
9805,104,69,0,23,272,1,21,0,33,0,1,0,SCRN1;secernin 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0031965//nuclear membrane,GO:0006887//exocytosis;GO:0006508//proteolysis,GO:0016805//dipeptidase activity,-
9806,0,0,0,0,0,0,26,0,56,146,10,0,"SPOCK2;sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2",GO:0005578//proteinaceous extracellular matrix,GO:0007416//synapse assembly;GO:0030198//extracellular matrix organization;GO:0045595//regulation of cell differentiation;GO:0019800//peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan;GO:0010811//positive regulation of cell-substrate adhesion;GO:0007165//signal transduction,GO:0050840//extracellular matrix binding;GO:0005539//glycosaminoglycan binding;GO:0005509//calcium ion binding,-
9807,0,48,0,0,1,0,0,4,1,0,12,0,IP6K1;inositol hexakisphosphate kinase 1,GO:0005730//nucleolus;GO:0005829//cytosol;GO:0005634//nucleus;GO:0005654//nucleoplasm,GO:0044281//small molecule metabolic process;GO:0046854//phosphatidylinositol phosphorylation;GO:0043647//inositol phosphate metabolic process,"GO:0052723//inositol hexakisphosphate 1-kinase activity;GO:0000832//inositol hexakisphosphate 5-kinase activity;GO:0005524//ATP binding;GO:0052724//inositol hexakisphosphate 3-kinase activity;GO:0008440//inositol-1,4,5-trisphosphate 3-kinase activity",-
9810,102,64,0,5,32,20,16,34,47,0,41,0,"RNF40;ring finger protein 40, E3 ubiquitin protein ligase",GO:0005634//nucleus;GO:0033503//HULC complex;GO:0000151//ubiquitin ligase complex;GO:0016020//membrane;GO:0043005//neuron projection,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0033523//histone H2B ubiquitination;GO:0010390//histone monoubiquitination,GO:0031625//ubiquitin protein ligase binding;GO:0017075//syntaxin-1 binding;GO:0016874//ligase activity;GO:0032403//protein complex binding;GO:0042803//protein homodimerization activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity;GO:0008270//zinc ion binding,-
9811,0,0,0,1,17,10,44,0,31,0,8,0,CTIF;CBP80/20-dependent translation initiation factor,GO:0005737//cytoplasm;GO:0048471//perinuclear region of cytoplasm,"GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006446//regulation of translational initiation",GO:0005515//protein binding;GO:0003723//RNA binding,K14322//RNA transport
9812,105,0,1,0,16,0,0,0,63,0,4,1,KIAA0141;KIAA0141,GO:0005739//mitochondrion,GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0005515//protein binding,-
9813,0,50,2,40,145,0,0,85,67,0,0,0,EFCAB14;EF-hand calcium binding domain 14,-,-,GO:0005509//calcium ion binding,K13999//Protein processing in endoplasmic reticulum;K04648//Vasopressin-regulated water reabsorption;Huntington's disease;K14570//Ribosome biogenesis in eukaryotes
9814,93,36,0,0,16,0,25,0,12,0,6,0,"SFI1;Sfi1 homolog, spindle assembly associated (yeast)",GO:0005814//centriole;GO:0005829//cytosol,GO:0000278//mitotic cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0010923//negative regulation of phosphatase activity,GO:0005515//protein binding;GO:0019902//phosphatase binding,-
9815,0,4,18,16,25,22,0,23,15,0,28,27,GIT2;G protein-coupled receptor kinase interacting ArfGAP 2,GO:0005925//focal adhesion;GO:0005654//nucleoplasm,GO:0008277//regulation of G-protein coupled receptor protein signaling pathway;GO:0043547//positive regulation of GTPase activity;GO:0032312//regulation of ARF GTPase activity;GO:0048266//behavioral response to pain,GO:0008270//zinc ion binding;GO:0008060//ARF GTPase activator activity;GO:0005515//protein binding,K12487//Endocytosis
9816,0,0,0,0,0,15,21,0,40,0,0,0,URB2;URB2 ribosome biogenesis 2 homolog (S. cerevisiae),GO:0005730//nucleolus;GO:0016235//aggresome;GO:0005634//nucleus,-,-,-
9817,0,0,0,9,7,0,0,0,7,0,2,0,KEAP1;kelch-like ECH-associated protein 1,GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0005783//endoplasmic reticulum;GO:0005730//nucleolus;GO:0030496//midbody;GO:0005815//microtubule organizing center;GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0071353//cellular response to interleukin-4;GO:0001701//in utero embryonic development;GO:0016567//protein ubiquitination;GO:0045604//regulation of epidermal cell differentiation;GO:0010499//proteasomal ubiquitin-independent protein catabolic process;GO:0006355//regulation of transcription, DNA-templated",GO:0005515//protein binding,K10456//Ubiquitin mediated proteolysis
9818,0,2,0,38,51,0,56,16,48,129,1,0,NUPL1;nucleoporin like 1,GO:0031965//nuclear membrane;GO:0005643//nuclear pore;GO:0005635//nuclear envelope,GO:0015758//glucose transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0005975//carbohydrate metabolic process;GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0006913//nucleocytoplasmic transport;GO:0044281//small molecule metabolic process,GO:0005487//nucleocytoplasmic transporter activity;GO:0005515//protein binding,K14307//RNA transport
9819,0,47,0,0,3,0,23,0,66,0,1,0,"TSC22D2;TSC22 domain family, member 2",-,"GO:0006355//regulation of transcription, DNA-templated;GO:0006970//response to osmotic stress",GO:0003700//sequence-specific DNA binding transcription factor activity,-
9820,39,9,1,16,10,14,24,1,26,17,17,368,CUL7;cullin 7,GO:0005794//Golgi apparatus;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0005730//nucleolus;GO:0005680//anaphase-promoting complex;GO:0005829//cytosol;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0001570//vasculogenesis;GO:0030968//endoplasmic reticulum unfolded protein response;GO:0007088//regulation of mitosis;GO:0001837//epithelial to mesenchymal transition;GO:0016032//viral process;GO:0050775//positive regulation of dendrite morphogenesis;GO:0000281//mitotic cytokinesis;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0044267//cellular protein metabolic process;GO:0016567//protein ubiquitination;GO:0007030//Golgi organization;GO:0000226//microtubule cytoskeleton organization;GO:0001890//placenta development;GO:0006508//proteolysis;GO:0006987//activation of signaling protein activity involved in unfolded protein response,GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding,K10613//Ubiquitin mediated proteolysis
9821,0,56,1,83,156,20,0,0,83,0,0,0,RB1CC1;RB1-inducible coiled-coil 1,GO:0031965//nuclear membrane;GO:0005737//cytoplasm;GO:0034045//pre-autophagosomal structure membrane;GO:0005829//cytosol;GO:0070969//ULK1-ATG13-FIP200 complex,"GO:0006351//transcription, DNA-templated;GO:0043066//negative regulation of apoptotic process;GO:0001934//positive regulation of protein phosphorylation;GO:0000045//autophagic vacuole assembly;GO:0001889//liver development;GO:2001237//negative regulation of extrinsic apoptotic signaling pathway;GO:0007049//cell cycle;GO:0007254//JNK cascade;GO:0010506//regulation of autophagy;GO:0007507//heart development;GO:0045793//positive regulation of cell size;GO:0006355//regulation of transcription, DNA-templated",GO:0019901//protein kinase binding;GO:0005515//protein binding,K12478//Phagosome;Endocytosis;Tuberculosis;K10352//Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection;Viral myocarditis;Hypertrophic cardiomyopathy (HCM);Regulation of actin cytoskeleton;Vascular smooth muscle contraction
9823,0,0,24,6,13,18,0,0,43,0,0,0,"ARMCX2;armadillo repeat containing, X-linked 2",GO:0016021//integral component of membrane,-,-,-
9824,0,0,0,0,10,23,44,71,48,0,0,0,ARHGAP11A;Rho GTPase activating protein 11A,GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity,K07526//Axon guidance
9825,174,47,0,0,33,34,16,0,27,0,0,0,SPATA2;spermatogenesis associated 2,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0030154//cell differentiation;GO:0007275//multicellular organismal development;GO:0007283//spermatogenesis,-,-
9826,0,3,0,0,42,25,43,60,71,111,20,1,ARHGEF11;Rho guanine nucleotide exchange factor (GEF) 11,GO:0005737//cytoplasm;GO:0005622//intracellular;GO:0016020//membrane;GO:0005829//cytosol,"GO:0000910//cytokinesis;GO:0006941//striated muscle contraction;GO:0032321//positive regulation of Rho GTPase activity;GO:0038032//termination of G-protein coupled receptor signaling pathway;GO:0007266//Rho protein signal transduction;GO:0006928//cellular component movement;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0001558//regulation of cell growth;GO:0030010//establishment of cell polarity;GO:0045893//positive regulation of transcription, DNA-templated;GO:0007264//small GTPase mediated signal transduction;GO:0030036//actin cytoskeleton organization;GO:0007411//axon guidance;GO:0007186//G-protein coupled receptor signaling pathway",GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005515//protein binding;GO:0001664//G-protein coupled receptor binding;GO:0005096//GTPase activator activity,K12331//Vascular smooth muscle contraction
9827,0,0,0,0,2,0,14,0,31,0,1,0,RGP1;RGP1 retrograde golgi transport homolog (S. cerevisiae),GO:0016020//membrane;GO:0005829//cytosol;GO:0043234//protein complex,"GO:0042147//retrograde transport, endosome to Golgi;GO:0032851//positive regulation of Rab GTPase activity",GO:0017137//Rab GTPase binding;GO:0017112//Rab guanyl-nucleotide exchange factor activity;GO:0005515//protein binding,-
9828,129,0,0,15,0,22,0,82,97,14,28,1,ARHGEF17;Rho guanine nucleotide exchange factor (GEF) 17,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0032321//positive regulation of Rho GTPase activity;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007264//small GTPase mediated signal transduction;GO:0097190//apoptotic signaling pathway;GO:0043065//positive regulation of apoptotic process;GO:0030036//actin cytoskeleton organization,GO:0005089//Rho guanyl-nucleotide exchange factor activity;GO:0005085//guanyl-nucleotide exchange factor activity,K04436//MAPK signaling pathway;K05156//Cytokine-cytokine receptor interaction;K01634//Sphingolipid metabolism;Metabolic pathways
9829,0,0,0,0,28,0,0,0,66,0,3,0,"DNAJC6;DnaJ (Hsp40) homolog, subfamily C, member 6",GO:0005829//cytosol;GO:0045202//synapse,GO:0072318//clathrin coat disassembly;GO:0061024//membrane organization;GO:2000369//regulation of clathrin-mediated endocytosis;GO:0008219//cell death;GO:0006892//post-Golgi vesicle-mediated transport;GO:0035335//peptidyl-tyrosine dephosphorylation,GO:0017124//SH3 domain binding;GO:0004725//protein tyrosine phosphatase activity,K09526//Endocytosis
983,0,0,0,0,0,0,24,0,26,0,5,0,CDK1;cyclin-dependent kinase 1,GO:0016020//membrane;GO:0070062//extracellular vesicular exosome;GO:0072686//mitotic spindle;GO:0005654//nucleoplasm;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005739//mitochondrion;GO:0005829//cytosol;GO:0030496//midbody;GO:0005876//spindle microtubule;GO:0005634//nucleus,"GO:0014075//response to amine;GO:0007095//mitotic G2 DNA damage checkpoint;GO:0034134//toll-like receptor 2 signaling pathway;GO:0046686//response to cadmium ion;GO:0007411//axon guidance;GO:0051403//stress-activated MAPK cascade;GO:0038124//toll-like receptor TLR6:TLR2 signaling pathway;GO:0002756//MyD88-independent toll-like receptor signaling pathway;GO:0018105//peptidyl-serine phosphorylation;GO:0045995//regulation of embryonic development;GO:0000086//G2/M transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0000278//mitotic cell cycle;GO:0060045//positive regulation of cardiac muscle cell proliferation;GO:0007265//Ras protein signal transduction;GO:0002755//MyD88-dependent toll-like receptor signaling pathway;GO:0034138//toll-like receptor 3 signaling pathway;GO:0009636//response to toxic substance;GO:0034501//protein localization to kinetochore;GO:0043066//negative regulation of apoptotic process;GO:0034142//toll-like receptor 4 signaling pathway;GO:0010628//positive regulation of gene expression;GO:0016477//cell migration;GO:0033160//positive regulation of protein import into nucleus, translocation;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0034162//toll-like receptor 9 signaling pathway;GO:0048678//response to axon injury;GO:0008286//insulin receptor signaling pathway;GO:0018107//peptidyl-threonine phosphorylation;GO:0042493//response to drug;GO:0031100//organ regeneration;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0008543//fibroblast growth factor receptor signaling pathway;GO:0034166//toll-like receptor 10 signaling pathway;GO:0070301//cellular response to hydrogen peroxide;GO:0002224//toll-like receptor signaling pathway;GO:0000187//activation of MAPK activity;GO:0000165//MAPK cascade;GO:0045471//response to ethanol;GO:0007077//mitotic nuclear envelope disassembly;GO:0006281//DNA repair;GO:0055015//ventricular cardiac muscle cell development;GO:0007067//mitotic nuclear division;GO:0016572//histone phosphorylation;GO:0007344//pronuclear fusion;GO:0014038//regulation of Schwann cell differentiation;GO:0006915//apoptotic process;GO:0007569//cell aging;GO:0045740//positive regulation of DNA replication;GO:0035666//TRIF-dependent toll-like receptor signaling pathway;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0007098//centrosome cycle;GO:0045931//positive regulation of mitotic cell cycle;GO:0045087//innate immune response;GO:0006461//protein complex assembly;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0007264//small GTPase mediated signal transduction;GO:0000186//activation of MAPKK activity;GO:0034146//toll-like receptor 5 signaling pathway;GO:0014823//response to activity;GO:0014070//response to organic cyclic compound;GO:0000082//G1/S transition of mitotic cell cycle;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0046688//response to copper ion;GO:0030261//chromosome condensation;GO:0038123//toll-like receptor TLR1:TLR2 signaling pathway;GO:0030855//epithelial cell differentiation;GO:0000226//microtubule cytoskeleton organization",GO:0008353//RNA polymerase II carboxy-terminal domain kinase activity;GO:0004693//cyclin-dependent protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding;GO:0005524//ATP binding;GO:0035173//histone kinase activity;GO:0004672//protein kinase activity;GO:0030332//cyclin binding;GO:0030544//Hsp70 protein binding,K02087//Oocyte meiosis;Gap junction;Herpes simplex infection;Epstein-Barr virus infection;Progesterone-mediated oocyte maturation;Cell cycle;p53 signaling pathway
9830,0,23,0,8,19,0,0,42,30,13,0,102,TRIM14;tripartite motif containing 14,GO:0005622//intracellular;GO:0005737//cytoplasm,GO:0051092//positive regulation of NF-kappaB transcription factor activity;GO:0032897//negative regulation of viral transcription;GO:0045087//innate immune response;GO:0051091//positive regulation of sequence-specific DNA binding transcription factor activity,GO:0008270//zinc ion binding,-
9831,40,1,0,16,23,0,51,51,7,0,0,0,ZNF623;zinc finger protein 623,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003677//DNA binding,-
9832,29,0,0,0,0,70,62,2,73,0,0,0,JAKMIP2;janus kinase and microtubule interacting protein 2,GO:0005794//Golgi apparatus,-,GO:0019900//kinase binding;GO:0008017//microtubule binding,K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways
9833,0,0,0,0,0,15,0,0,31,0,10,0,MELK;maternal embryonic leucine zipper kinase,GO:0005938//cell cortex;GO:0016020//membrane;GO:0005886//plasma membrane,GO:0046777//protein autophosphorylation;GO:0008631//intrinsic apoptotic signaling pathway in response to oxidative stress;GO:0043065//positive regulation of apoptotic process;GO:0000086//G2/M transition of mitotic cell cycle;GO:0018108//peptidyl-tyrosine phosphorylation;GO:0008283//cell proliferation;GO:0061351//neural precursor cell proliferation;GO:0006915//apoptotic process;GO:0030097//hemopoiesis,GO:0004715//non-membrane spanning protein tyrosine kinase activity;GO:0005524//ATP binding;GO:0008289//lipid binding;GO:0005515//protein binding;GO:0004674//protein serine/threonine kinase activity;GO:0005509//calcium ion binding,-
9834,0,0,0,0,0,0,29,0,65,98,14,0,KIAA0125;KIAA0125,-,-,-,K05185//Retrograde endocannabinoid signaling;Neuroactive ligand-receptor interaction;GABAergic synapse;Morphine addiction;Nicotine addiction
9836,103,7,63,15,21,0,3,0,0,0,2,0,LCMT2;leucine carboxyl methyltransferase 2,-,GO:0032259//methylation;GO:0008033//tRNA processing,GO:0008168//methyltransferase activity;GO:0005515//protein binding,-
9837,0,0,0,0,0,20,0,0,72,0,0,0,GINS1;GINS complex subunit 1 (Psf1 homolog),GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005654//nucleoplasm,GO:0000278//mitotic cell cycle;GO:0001833//inner cell mass cell proliferation;GO:0006271//DNA strand elongation involved in DNA replication,-,-
9839,0,0,0,0,0,7,0,0,37,0,9,0,ZEB2;zinc finger E-box binding homeobox 2,GO:0005634//nucleus,"GO:0021766//hippocampus development;GO:0097324//melanocyte migration;GO:0001756//somitogenesis;GO:0006351//transcription, DNA-templated;GO:0021846//cell proliferation in forebrain;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048023//positive regulation of melanin biosynthetic process;GO:0048066//developmental pigmentation;GO:0001843//neural tube closure;GO:0045636//positive regulation of melanocyte differentiation;GO:0043507//positive regulation of JUN kinase activity;GO:1903056//regulation of melanosome organization;GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0030177//positive regulation of Wnt signaling pathway",GO:0070412//R-SMAD binding;GO:0019208//phosphatase regulator activity;GO:0046872//metal ion binding;GO:0003677//DNA binding,K09299//Transcriptional misregulation in cancer
984,0,0,0,0,0,0,0,0,7,0,12,0,CDK11B;cyclin-dependent kinase 11B,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0007067//mitotic nuclear division;GO:0050684//regulation of mRNA processing;GO:0006355//regulation of transcription, DNA-templated;GO:0001558//regulation of cell growth;GO:0006468//protein phosphorylation;GO:0051726//regulation of cell cycle;GO:0006915//apoptotic process;GO:0008283//cell proliferation",GO:0004674//protein serine/threonine kinase activity;GO:0004672//protein kinase activity;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0005524//ATP binding;GO:0004693//cyclin-dependent protein serine/threonine kinase activity,-
9840,0,0,0,0,0,0,15,2,18,0,22,0,"TESPA1;thymocyte expressed, positive selection associated 1",GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0008180//COP9 signalosome,GO:0050862//positive regulation of T cell receptor signaling pathway;GO:0033089//positive regulation of T cell differentiation in thymus;GO:0010387//COP9 signalosome assembly,GO:0005102//receptor binding,-
9841,157,0,0,0,11,0,0,0,14,9,9,0,ZBTB24;zinc finger and BTB domain containing 24,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0002244//hematopoietic progenitor cell differentiation",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0046872//metal ion binding,-
9842,9,0,0,0,6,0,42,0,1,1,0,0,"PLEKHM1;pleckstrin homology domain containing, family M (with RUN domain) member 1",GO:0005737//cytoplasm,GO:0035556//intracellular signal transduction,GO:0046872//metal ion binding,K15348//Salmonella infection
9843,0,0,0,0,0,0,63,0,62,0,3,0,HEPH;hephaestin,GO:0048471//perinuclear region of cytoplasm;GO:0005886//plasma membrane;GO:0005622//intracellular;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport;GO:0006879//cellular iron ion homeostasis;GO:0055085//transmembrane transport;GO:0006826//iron ion transport,GO:0005507//copper ion binding;GO:0008198//ferrous iron binding;GO:0004322//ferroxidase activity,K14735//Mineral absorption
9844,0,0,52,0,0,8,0,0,53,0,1,2,ELMO1;engulfment and cell motility 1,GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005856//cytoskeleton,"GO:0016032//viral process;GO:0045087//innate immune response;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0016601//Rac protein signal transduction;GO:0030036//actin cytoskeleton organization;GO:0006915//apoptotic process;GO:0006911//phagocytosis, engulfment;GO:0006928//cellular component movement;GO:0050690//regulation of defense response to virus by virus",GO:0005515//protein binding;GO:0017124//SH3 domain binding,K12366//Bacterial invasion of epithelial cells;Chemokine signaling pathway;Shigellosis
9846,0,0,0,0,9,27,0,15,32,0,11,0,GAB2;GRB2-associated binding protein 2,GO:0005829//cytosol;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0016477//cell migration;GO:0008284//positive regulation of cell proliferation;GO:0045087//innate immune response;GO:0043306//positive regulation of mast cell degranulation;GO:0007229//integrin-mediated signaling pathway;GO:0030316//osteoclast differentiation;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0007169//transmembrane receptor protein tyrosine kinase signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling,"GO:0005068//transmembrane receptor protein tyrosine kinase adaptor activity;GO:0043325//phosphatidylinositol-3,4-bisphosphate binding;GO:0005547//phosphatidylinositol-3,4,5-trisphosphate binding;GO:0005515//protein binding",K08091//Fc gamma R-mediated phagocytosis;Osteoclast differentiation;Chronic myeloid leukemia;Fc epsilon RI signaling pathway
9847,14,26,0,2,45,29,0,0,51,0,0,0,C2CD5;C2 calcium-dependent domain containing 5,GO:0030659//cytoplasmic vesicle membrane;GO:0032587//ruffle membrane;GO:0005886//plasma membrane;GO:0005938//cell cortex,GO:0032869//cellular response to insulin stimulus;GO:0038028//insulin receptor signaling pathway via phosphatidylinositol 3-kinase;GO:0031340//positive regulation of vesicle fusion;GO:0090314//positive regulation of protein targeting to membrane;GO:0065002//intracellular protein transmembrane transport;GO:0010828//positive regulation of glucose transport,GO:0005509//calcium ion binding;GO:0005544//calcium-dependent phospholipid binding,K15290//Synaptic vesicle cycle;K06130//Glycerophospholipid metabolism
9848,0,0,0,0,0,16,0,0,0,0,0,0,MFAP3L;microfibrillar-associated protein 3-like,GO:0016021//integral component of membrane;GO:0005886//plasma membrane,-,-,K06757//Cell adhesion molecules (CAMs)
9849,0,0,46,11,60,44,59,0,16,0,12,0,ZNF518A;zinc finger protein 518A,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046872//metal ion binding,-
9851,0,0,0,9,28,24,42,1,70,0,41,0,KIAA0753;KIAA0753,GO:0005813//centrosome;GO:0005737//cytoplasm,-,-,-
9852,0,72,50,26,132,0,66,0,40,0,0,0,EPM2AIP1;EPM2A (laforin) interacting protein 1,GO:0005634//nucleus;GO:0005783//endoplasmic reticulum,GO:2000467//positive regulation of glycogen (starch) synthase activity;GO:0045725//positive regulation of glycogen biosynthetic process;GO:0032868//response to insulin,-,K06264//ECM-receptor interaction;K14209//Protein digestion and absorption;K09057//Circadian rhythm - fly
9853,0,0,0,0,21,16,0,0,35,0,1,0,RUSC2;RUN and SH3 domain containing 2,GO:0031410//cytoplasmic vesicle;GO:0070062//extracellular vesicular exosome;GO:0005829//cytosol,-,GO:0017137//Rab GTPase binding;GO:0005515//protein binding,-
9854,19,0,0,0,0,13,0,27,39,1,0,0,C2CD2L;C2CD2-like,GO:0016021//integral component of membrane,-,-,-
9855,167,61,1,13,93,1,56,70,118,95,72,0,"FARP2;FERM, RhoGEF and pleckstrin domain protein 2",GO:0005737//cytoplasm;GO:0019898//extrinsic component of membrane;GO:0005856//cytoskeleton;GO:0005829//cytosol,GO:0071526//semaphorin-plexin signaling pathway;GO:0007155//cell adhesion;GO:0031532//actin cytoskeleton reorganization;GO:0007411//axon guidance;GO:0032855//positive regulation of Rac GTPase activity;GO:0030316//osteoclast differentiation;GO:0016322//neuron remodeling;GO:0016601//Rac protein signal transduction;GO:0032314//regulation of Rac GTPase activity;GO:0071800//podosome assembly;GO:0032321//positive regulation of Rho GTPase activity;GO:0033623//regulation of integrin activation,GO:0008092//cytoskeletal protein binding;GO:0030676//Rac guanyl-nucleotide exchange factor activity;GO:0005089//Rho guanyl-nucleotide exchange factor activity,K06082//Adherens junction
9856,0,0,0,0,0,3,0,0,63,0,17,0,KIAA0319;KIAA0319,GO:0005769//early endosome;GO:0005886//plasma membrane;GO:0031901//early endosome membrane;GO:0016021//integral component of membrane,GO:0001764//neuron migration;GO:2000171//negative regulation of dendrite development,GO:0005515//protein binding,K15619//Transcriptional misregulation in cancer
9857,0,36,52,26,104,50,30,0,88,147,0,734,CEP350;centrosomal protein 350kDa,GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005730//nucleolus;GO:0016020//membrane,GO:0034453//microtubule anchoring,GO:0008017//microtubule binding,-
9858,0,1,0,0,9,0,25,0,9,0,0,0,"PPP1R26;protein phosphatase 1, regulatory subunit 26",GO:0005730//nucleolus;GO:0005634//nucleus,GO:0010923//negative regulation of phosphatase activity,GO:0005515//protein binding;GO:0019902//phosphatase binding;GO:0004864//protein phosphatase inhibitor activity,-
9859,173,0,65,2,12,91,18,10,58,163,9,0,CEP170;centrosomal protein 170kDa,GO:0005814//centriole;GO:0005874//microtubule;GO:0031965//nuclear membrane;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0005813//centrosome,-,GO:0005515//protein binding,-
9860,0,0,0,0,0,28,0,0,46,0,0,0,LRIG2;leucine-rich repeats and immunoglobulin-like domains 2,GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0010640//regulation of platelet-derived growth factor receptor signaling pathway;GO:0060384//innervation;GO:0007605//sensory perception of sound,-,K06753//Axon guidance
9861,0,54,0,0,17,7,5,70,1,0,0,0,"PSMD6;proteasome (prosome, macropain) 26S subunit, non-ATPase, 6",GO:0005654//nucleoplasm;GO:0000502//proteasome complex;GO:0005829//cytosol;GO:0022624//proteasome accessory complex;GO:0070062//extracellular vesicular exosome,"GO:0006915//apoptotic process;GO:0006508//proteolysis;GO:0042590//antigen processing and presentation of exogenous peptide antigen via MHC class I;GO:0000278//mitotic cell cycle;GO:0034641//cellular nitrogen compound metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0042981//regulation of apoptotic process;GO:0016032//viral process;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006200//ATP catabolic process;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000209//protein polyubiquitination;GO:0006521//regulation of cellular amino acid metabolic process;GO:0043066//negative regulation of apoptotic process;GO:0010467//gene expression;GO:0006977//DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0002479//antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0044281//small molecule metabolic process",GO:0016887//ATPase activity,K03037//Proteasome;Epstein-Barr virus infection
9862,0,0,0,18,1,4,74,68,28,0,1,0,MED24;mediator complex subunit 24,GO:0005634//nucleus;GO:0016592//mediator complex;GO:0005654//nucleoplasm,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0010467//gene expression;GO:0019827//stem cell maintenance;GO:0051291//protein heterooligomerization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0016573//histone acetylation;GO:0030521//androgen receptor signaling pathway;GO:0006357//regulation of transcription from RNA polymerase II promoter;GO:0030518//intracellular steroid hormone receptor signaling pathway",GO:0004872//receptor activity;GO:0046966//thyroid hormone receptor binding;GO:0003712//transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042809//vitamin D receptor binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0004402//histone acetyltransferase activity,-
9865,0,0,0,0,0,0,0,43,53,0,1,8,TRIL;TLR4 interactor with leucine-rich repeats,GO:0046696//lipopolysaccharide receptor complex,GO:0006954//inflammatory response;GO:0045087//innate immune response;GO:0002718//regulation of cytokine production involved in immune response;GO:0034142//toll-like receptor 4 signaling pathway,GO:0001530//lipopolysaccharide binding,-
9866,69,0,0,0,0,35,26,0,45,0,11,0,TRIM66;tripartite motif containing 66,GO:0005634//nucleus;GO:0016235//aggresome;GO:0005730//nucleolus,-,GO:0008270//zinc ion binding,-
9867,82,90,0,218,552,32,14,0,0,0,34,0,"PJA2;praja ring finger 2, E3 ubiquitin protein ligase",GO:0005886//plasma membrane;GO:0030054//cell junction;GO:0045211//postsynaptic membrane;GO:0000139//Golgi membrane;GO:0005737//cytoplasm;GO:0014069//postsynaptic density;GO:0005789//endoplasmic reticulum membrane,GO:0010738//regulation of protein kinase A signaling;GO:0007616//long-term memory;GO:0016567//protein ubiquitination,GO:0008270//zinc ion binding;GO:0034236//protein kinase A catalytic subunit binding;GO:0016874//ligase activity;GO:0034237//protein kinase A regulatory subunit binding;GO:0004842//ubiquitin-protein transferase activity,-
9868,0,2,19,106,268,8,0,0,29,0,29,0,TOMM70A;translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae),GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005742//mitochondrial outer membrane translocase complex;GO:0005739//mitochondrion,GO:0006626//protein targeting to mitochondrion;GO:0071806//protein transmembrane transport;GO:0044267//cellular protein metabolic process,GO:0008320//protein transmembrane transporter activity;GO:0005515//protein binding,-
9869,0,0,0,35,61,3,75,54,14,0,54,320,"SETDB1;SET domain, bifurcated 1",GO:0005886//plasma membrane;GO:0005730//nucleolus;GO:0005794//Golgi apparatus;GO:0005737//cytoplasm;GO:0000790//nuclear chromatin;GO:0005634//nucleus,"GO:0001833//inner cell mass cell proliferation;GO:0036124//histone H3-K9 trimethylation;GO:0006351//transcription, DNA-templated;GO:0060348//bone development;GO:0000122//negative regulation of transcription from RNA polymerase II promoter",GO:0018024//histone-lysine N-methyltransferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0003677//DNA binding,K11421//Lysine degradation
987,0,148,3,314,1138,9,1,98,90,0,0,0,"LRBA;LPS-responsive vesicle trafficking, beach and anchor containing",GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005783//endoplasmic reticulum;GO:0016023//cytoplasmic membrane-bounded vesicle;GO:0005886//plasma membrane;GO:0005794//Golgi apparatus;GO:0005764//lysosome,-,-,-
9870,147,16,0,8,29,73,1,0,48,0,0,0,AREL1;apoptosis resistant E3 ubiquitin protein ligase 1,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol,GO:0042787//protein ubiquitination involved in ubiquitin-dependent protein catabolic process;GO:0006915//apoptotic process;GO:0043066//negative regulation of apoptotic process,GO:0016874//ligase activity;GO:0004842//ubiquitin-protein transferase activity,K13305//Ubiquitin mediated proteolysis;Aldosterone-regulated sodium reabsorption;Endocytosis;K10591//Ubiquitin mediated proteolysis;Epstein-Barr virus infection;Endocytosis
9871,0,4,2,31,119,1,1,0,22,0,0,0,SEC24D;SEC24 family member D,GO:0030127//COPII vesicle coat;GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0048471//perinuclear region of cytoplasm;GO:0005789//endoplasmic reticulum membrane;GO:0012507//ER to Golgi transport vesicle membrane,GO:0019886//antigen processing and presentation of exogenous peptide antigen via MHC class II;GO:0061024//membrane organization;GO:0044267//cellular protein metabolic process;GO:0002474//antigen processing and presentation of peptide antigen via MHC class I;GO:0043687//post-translational protein modification;GO:0001701//in utero embryonic development;GO:0048208//COPII vesicle coating;GO:0044281//small molecule metabolic process;GO:0006888//ER to Golgi vesicle-mediated transport;GO:0018279//protein N-linked glycosylation via asparagine;GO:0006886//intracellular protein transport,GO:0008270//zinc ion binding,K14007//Protein processing in endoplasmic reticulum
9873,83,24,0,0,0,0,20,63,27,0,0,0,FCHSD2;FCH and double SH3 domains 2,-,-,GO:0005515//protein binding,K07526//Axon guidance
9874,0,1,0,19,83,29,0,0,46,0,0,0,TLK1;tousled-like kinase 1,GO:0005634//nucleus,GO:0006974//cellular response to DNA damage stimulus;GO:0016568//chromatin modification;GO:0001672//regulation of chromatin assembly or disassembly;GO:0007049//cell cycle;GO:0006468//protein phosphorylation;GO:0006886//intracellular protein transport;GO:0035556//intracellular signal transduction,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity,-
9875,236,1,1,12,63,21,42,67,125,254,30,0,URB1;URB1 ribosome biogenesis 1 homolog (S. cerevisiae),GO:0005730//nucleolus,-,GO:0044822//poly(A) RNA binding,-
9877,0,42,2,67,210,0,43,57,32,1,8,0,ZC3H11A;zinc finger CCCH-type containing 11A,GO:0000346//transcription export complex,GO:0016973//poly(A)+ mRNA export from nucleus,GO:0046872//metal ion binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,K04157//Gap junction;Neuroactive ligand-receptor interaction;Serotonergic synapse;Calcium signaling pathway
9878,0,585,365,591,987,0,47,312,114,0,666,0,TOX4;TOX high mobility group box family member 4,GO:0005634//nucleus;GO:0000785//chromatin;GO:0005730//nucleolus;GO:0072357//PTW/PP1 phosphatase complex,-,GO:0005515//protein binding;GO:0003677//DNA binding,K00939//Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Metabolic pathways
988,3,24,1,26,56,10,71,0,27,0,0,0,CDC5L;cell division cycle 5-like,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0000974//Prp19 complex;GO:0005730//nucleolus;GO:0071013//catalytic step 2 spliceosome;GO:0016020//membrane;GO:0016607//nuclear speck,"GO:0000398//mRNA splicing, via spliceosome;GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated;GO:0007049//cell cycle",GO:0003677//DNA binding;GO:0005515//protein binding;GO:0044822//poly(A) RNA binding;GO:0003682//chromatin binding;GO:0071987//WD40-repeat domain binding,K12860//Spliceosome
9880,36,0,0,6,38,37,44,0,8,224,6,0,ZBTB39;zinc finger and BTB domain containing 39,GO:0005634//nucleus,"GO:0006351//transcription, DNA-templated;GO:0006355//regulation of transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9881,87,1,0,13,3,0,27,0,49,0,0,0,TRANK1;tetratricopeptide repeat and ankyrin repeat containing 1,-,GO:0008152//metabolic process,GO:0016787//hydrolase activity;GO:0005524//ATP binding,-
9882,0,1,2,61,61,3,48,55,99,0,24,0,"TBC1D4;TBC1 domain family, member 4",GO:0005737//cytoplasm;GO:0030659//cytoplasmic vesicle membrane;GO:0070062//extracellular vesicular exosome,GO:0061024//membrane organization;GO:0032851//positive regulation of Rab GTPase activity;GO:0032869//cellular response to insulin stimulus;GO:0031339//negative regulation of vesicle fusion;GO:0016192//vesicle-mediated transport,GO:0005097//Rab GTPase activator activity,K13136//RNA transport
9883,44,107,120,28,50,2,1,108,81,0,138,1,POM121;POM121 transmembrane nucleoporin,GO:0005789//endoplasmic reticulum membrane;GO:0031965//nuclear membrane;GO:0005635//nuclear envelope;GO:0005643//nuclear pore,GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0005975//carbohydrate metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0044281//small molecule metabolic process;GO:0015758//glucose transport;GO:0019221//cytokine-mediated signaling pathway;GO:0015031//protein transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport,-,K14316//RNA transport
9884,0,83,1,38,38,15,0,3,2,0,53,0,LRRC37A;leucine rich repeat containing 37A,GO:0016021//integral component of membrane,-,-,K04306//Neuroactive ligand-receptor interaction;K06839//Axon guidance
9885,0,0,0,0,0,25,0,79,27,0,0,0,OSBPL2;oxysterol binding protein-like 2,-,GO:0006869//lipid transport,GO:0015485//cholesterol binding,K01539//Mineral absorption;Pancreatic secretion;Endocrine and other factor-regulated calcium reabsorption;Aldosterone-regulated sodium reabsorption;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Oxidative phosphorylation;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Bile secretion;K11447//Transcriptional misregulation in cancer;K00939//Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
9886,0,0,33,15,2,30,1,52,2,83,7,0,RHOBTB1;Rho-related BTB domain containing 1,GO:0005829//cytosol;GO:0005886//plasma membrane,GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005525//GTP binding,K07868//Ubiquitin mediated proteolysis
9887,0,3,20,58,218,11,0,46,31,0,0,0,SMG7;SMG7 nonsense mediated mRNA decay factor,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005829//cytosol;GO:0045111//intermediate filament cytoskeleton,"GO:0035303//regulation of dephosphorylation;GO:0016070//RNA metabolic process;GO:0016071//mRNA metabolic process;GO:0010467//gene expression;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006406//mRNA export from nucleus",GO:0005515//protein binding;GO:0051721//protein phosphatase 2A binding,K14409//mRNA surveillance pathway
9889,48,31,0,0,25,0,0,0,22,0,6,0,"ZBED4;zinc finger, BED-type containing 4",GO:0005730//nucleolus;GO:0005737//cytoplasm;GO:0005634//nucleus,-,GO:0046872//metal ion binding;GO:0003677//DNA binding;GO:0046983//protein dimerization activity,K14303//RNA transport
989,0,0,1,24,35,0,0,0,19,0,0,0,SEPT7;septin 7,GO:0015630//microtubule cytoskeleton;GO:0001725//stress fiber;GO:0005634//nucleus;GO:0005930//axoneme;GO:0015629//actin cytoskeleton;GO:0030496//midbody;GO:0005730//nucleolus;GO:0005819//spindle;GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0032154//cleavage furrow;GO:0000777//condensed chromosome kinetochore;GO:0031105//septin complex;GO:0005886//plasma membrane;GO:0070062//extracellular vesicular exosome,GO:0007067//mitotic nuclear division;GO:0051291//protein heterooligomerization;GO:0000910//cytokinesis;GO:0016476//regulation of embryonic cell shape;GO:0060271//cilium morphogenesis,GO:0005515//protein binding;GO:0042802//identical protein binding;GO:0005198//structural molecule activity;GO:0005525//GTP binding,K04557//Parkinson's disease
9890,0,0,0,0,30,8,3,0,40,0,2,0,LPPR4;lipid phosphate phosphatase-related protein type 4,GO:0005887//integral component of plasma membrane,GO:0046839//phospholipid dephosphorylation;GO:0048839//inner ear development;GO:0007409//axonogenesis,GO:0042577//lipid phosphatase activity;GO:0008195//phosphatidate phosphatase activity,K01080//Sphingolipid metabolism;Ether lipid metabolism;Fc gamma R-mediated phagocytosis;Glycerophospholipid metabolism;Fat digestion and absorption;Metabolic pathways;Glycerolipid metabolism
9891,0,33,0,0,1,78,50,1,26,0,0,150,"NUAK1;NUAK family, SNF1-like kinase, 1",GO:0015630//microtubule cytoskeleton;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0007155//cell adhesion;GO:0035507//regulation of myosin-light-chain-phosphatase activity;GO:0006468//protein phosphorylation;GO:0030155//regulation of cell adhesion;GO:0042127//regulation of cell proliferation;GO:0006974//cellular response to DNA damage stimulus;GO:2000772//regulation of cellular senescence,GO:0005524//ATP binding;GO:0004674//protein serine/threonine kinase activity;GO:0002039//p53 binding;GO:0046872//metal ion binding;GO:0005515//protein binding,-
9892,14,0,0,0,42,17,24,0,79,141,8,0,"SNAP91;synaptosomal-associated protein, 91kDa",GO:0005905//coated pit;GO:0030118//clathrin coat;GO:0005886//plasma membrane,GO:0048268//clathrin coat assembly;GO:0015031//protein transport,GO:0030276//clathrin binding;GO:0005545//1-phosphatidylinositol binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
9894,0,0,0,0,0,0,16,1,54,0,12,0,TELO2;telomere maintenance 2,"GO:0016020//membrane;GO:0031932//TORC2 complex;GO:0005622//intracellular;GO:0000781//chromosome, telomeric region;GO:0031931//TORC1 complex;GO:0005634//nucleus;GO:0005737//cytoplasm",GO:0032006//regulation of TOR signaling,GO:0032403//protein complex binding;GO:0032947//protein complex scaffold;GO:0005515//protein binding,K11137//Fanconi anemia pathway
9895,107,1,0,26,13,0,22,4,68,0,17,0,TECPR2;tectonin beta-propeller repeat containing 2,-,GO:0006914//autophagy;GO:0008219//cell death,GO:0005515//protein binding,K00591//Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;Metabolic pathways
9896,0,22,1,9,35,34,22,0,36,0,0,0,"FIG4;FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)",GO:0031902//late endosome membrane;GO:0031901//early endosome membrane;GO:0000139//Golgi membrane;GO:0010008//endosome membrane,GO:0016311//dephosphorylation;GO:0032288//myelin assembly;GO:0006661//phosphatidylinositol biosynthetic process;GO:0007626//locomotory behavior;GO:0008219//cell death;GO:0007033//vacuole organization;GO:0006644//phospholipid metabolic process;GO:0010976//positive regulation of neuron projection development;GO:0044281//small molecule metabolic process;GO:0048666//neuron development;GO:0043473//pigmentation;GO:0036092//phosphatidylinositol-3-phosphate biosynthetic process;GO:0031642//negative regulation of myelination,"GO:0043812//phosphatidylinositol-4-phosphate phosphatase activity;GO:0005515//protein binding;GO:0004438//phosphatidylinositol-3-phosphatase activity;GO:0043813//phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity",K01099//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
9897,0,20,1,8,37,38,25,0,47,0,3,1,KIAA0196;KIAA0196,GO:0005783//endoplasmic reticulum;GO:0005829//cytosol;GO:0005768//endosome;GO:0071203//WASH complex,GO:0016197//endosomal transport;GO:0008219//cell death,-,-
9898,74,0,2,1,47,10,0,0,63,0,1,0,UBAP2L;ubiquitin associated protein 2-like,GO:0005671//Ada2/Gcn5/Ada3 transcription activator complex,GO:0007339//binding of sperm to zona pellucida,GO:0005515//protein binding;GO:0044822//poly(A) RNA binding,-
9899,47,2,1,18,155,4,19,17,60,0,0,0,SV2B;synaptic vesicle glycoprotein 2B,GO:0008021//synaptic vesicle;GO:0001669//acrosomal vesicle;GO:0016021//integral component of membrane;GO:0030054//cell junction;GO:0030672//synaptic vesicle membrane,GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0022857//transmembrane transporter activity,K06258//ECM-receptor interaction
990,0,0,0,0,0,1,23,0,21,0,8,0,CDC6;cell division cycle 6,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0005794//Golgi apparatus;GO:0051233//spindle midzone;GO:0005634//nucleus;GO:0000922//spindle pole;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0030071//regulation of mitotic metaphase/anaphase transition;GO:0000082//G1/S transition of mitotic cell cycle;GO:0000076//DNA replication checkpoint;GO:0032467//positive regulation of cytokinesis;GO:0051984//positive regulation of chromosome segregation;GO:0007067//mitotic nuclear division;GO:0008156//negative regulation of DNA replication;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0007089//traversing start control point of mitotic cell cycle;GO:0008285//negative regulation of cell proliferation;GO:0000083//regulation of transcription involved in G1/S transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0006260//DNA replication,GO:0003682//chromatin binding;GO:0005524//ATP binding;GO:0019900//kinase binding;GO:0000166//nucleotide binding;GO:0005515//protein binding,K02213//Cell cycle;Cell cycle - yeast;Meiosis - yeast
9900,0,0,0,0,0,5,35,1,31,0,2,0,SV2A;synaptic vesicle glycoprotein 2A,GO:0048786//presynaptic active zone;GO:0005911//cell-cell junction;GO:0005737//cytoplasm;GO:0043005//neuron projection;GO:0008021//synaptic vesicle;GO:0005783//endoplasmic reticulum;GO:0016021//integral component of membrane;GO:0031594//neuromuscular junction;GO:0030672//synaptic vesicle membrane,GO:0006874//cellular calcium ion homeostasis;GO:0006836//neurotransmitter transport;GO:0055085//transmembrane transport,GO:0019901//protein kinase binding;GO:0004872//receptor activity;GO:0022857//transmembrane transporter activity,K06258//ECM-receptor interaction
9901,92,0,0,1,5,25,33,54,57,0,10,0,SRGAP3;SLIT-ROBO Rho GTPase activating protein 3,GO:0005829//cytosol,GO:0007264//small GTPase mediated signal transduction;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005096//GTPase activator activity;GO:0005515//protein binding,K07526//Axon guidance
9902,0,0,0,0,0,16,81,0,22,0,3,0,"MRC2;mannose receptor, C type 2",GO:0005925//focal adhesion;GO:0016020//membrane;GO:0016021//integral component of membrane,GO:0006897//endocytosis;GO:0001649//osteoblast differentiation;GO:0030574//collagen catabolic process,GO:0005518//collagen binding;GO:0030246//carbohydrate binding;GO:0005515//protein binding,K06560//Phagosome;Tuberculosis
9903,0,0,1,1,30,16,60,0,29,0,18,0,KLHL21;kelch-like family member 21,GO:0005737//cytoplasm;GO:0005827//polar microtubule;GO:0031463//Cul3-RING ubiquitin ligase complex,GO:0035853//chromosome passenger complex localization to spindle midzone;GO:0007067//mitotic nuclear division;GO:0032465//regulation of cytokinesis;GO:0016567//protein ubiquitination,GO:0004842//ubiquitin-protein transferase activity,-
9904,30,0,0,4,19,0,76,0,24,235,8,0,RBM19;RNA binding motif protein 19,GO:0016020//membrane;GO:0005730//nucleolus;GO:0005694//chromosome;GO:0005654//nucleoplasm;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0040019//positive regulation of embryonic development;GO:0007275//multicellular organismal development,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding,-
9905,3,45,36,2,10,21,26,1,54,243,46,32,SGSM2;small G protein signaling modulator 2,-,GO:0032851//positive regulation of Rab GTPase activity;GO:0033126//positive regulation of GTP catabolic process;GO:0034499//late endosome to Golgi transport,GO:0005097//Rab GTPase activator activity;GO:0017137//Rab GTPase binding,K13136//RNA transport
9906,0,0,0,12,32,0,0,0,52,0,6,0,"SLC35E2;solute carrier family 35, member E2",GO:0016021//integral component of membrane,-,-,-
9907,0,0,1,0,7,0,0,102,17,0,0,0,"AP5Z1;adaptor-related protein complex 5, zeta 1 subunit",GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0044599//AP-5 adaptor complex;GO:0030119//AP-type membrane coat adaptor complex;GO:0005730//nucleolus,GO:0008219//cell death;GO:0016197//endosomal transport;GO:0000724//double-strand break repair via homologous recombination;GO:0015031//protein transport,GO:0005515//protein binding,-
9908,7,156,48,209,721,0,64,0,27,0,18,0,G3BP2;GTPase activating protein (SH3 domain) binding protein 2,GO:0005737//cytoplasm,GO:0007253//cytoplasmic sequestering of NF-kappaB;GO:0051028//mRNA transport;GO:0007265//Ras protein signal transduction,GO:0030159//receptor signaling complex scaffold activity;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding,K12741//Spliceosome;K03102//Dorso-ventral axis formation
9909,0,1,0,5,6,9,23,0,64,31,16,0,DENND4B;DENN/MADD domain containing 4B,GO:0005634//nucleus;GO:0005794//Golgi apparatus,GO:0032851//positive regulation of Rab GTPase activity,GO:0017112//Rab guanyl-nucleotide exchange factor activity,K12861//Spliceosome
991,0,0,0,0,0,0,0,0,1,2,0,0,CDC20;cell division cycle 20,GO:0005654//nucleoplasm;GO:0005819//spindle;GO:0005813//centrosome;GO:0005737//cytoplasm;GO:0000922//spindle pole;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm;GO:0005829//cytosol;GO:0005680//anaphase-promoting complex;GO:0005730//nucleolus,GO:0031915//positive regulation of synaptic plasticity;GO:0007094//mitotic spindle assembly checkpoint;GO:0000278//mitotic cell cycle;GO:0040020//regulation of meiosis;GO:0016567//protein ubiquitination;GO:0008284//positive regulation of cell proliferation;GO:0090129//positive regulation of synapse maturation;GO:0051488//activation of anaphase-promoting complex activity;GO:0050773//regulation of dendrite development;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0007067//mitotic nuclear division;GO:0007049//cell cycle,GO:0005515//protein binding;GO:0019899//enzyme binding;GO:0008022//protein C-terminus binding,K03363//Cell cycle;Ubiquitin mediated proteolysis;Cell cycle - yeast;Oocyte meiosis;HTLV-I infection;Meiosis - yeast
9910,87,21,0,12,57,27,19,0,48,0,8,257,RABGAP1L;RAB GTPase activating protein 1-like,GO:0005769//early endosome;GO:0005794//Golgi apparatus;GO:0005634//nucleus,GO:0032851//positive regulation of Rab GTPase activity;GO:0032880//regulation of protein localization,GO:0017137//Rab GTPase binding;GO:0005097//Rab GTPase activator activity,K11447//Transcriptional misregulation in cancer;K13136//RNA transport;K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism
9911,0,0,0,0,0,0,0,124,25,0,0,0,TMCC2;transmembrane and coiled-coil domain family 2,GO:0016021//integral component of membrane,-,GO:0005515//protein binding,K06757//Cell adhesion molecules (CAMs)
9912,14,0,0,0,7,27,71,0,73,0,47,0,ARHGAP44;Rho GTPase activating protein 44,GO:0005829//cytosol;GO:0030054//cell junction;GO:0045202//synapse;GO:0031256//leading edge membrane;GO:0055037//recycling endosome;GO:0043197//dendritic spine,GO:0006887//exocytosis;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction;GO:0043547//positive regulation of GTPase activity,GO:0005515//protein binding;GO:0005543//phospholipid binding;GO:0005096//GTPase activator activity,K13709//Focal adhesion;Leukocyte transendothelial migration;K05732//Leukocyte transendothelial migration;Focal adhesion;Regulation of actin cytoskeleton;K07526//Axon guidance
9913,107,0,34,23,70,0,0,0,42,0,0,293,SUPT7L;suppressor of Ty 7 (S. cerevisiae)-like,GO:0005634//nucleus;GO:0030914//STAGA complex,"GO:0043966//histone H3 acetylation;GO:0006325//chromatin organization;GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0051457//maintenance of protein location in nucleus",GO:0003713//transcription coactivator activity;GO:0004402//histone acetyltransferase activity;GO:0005515//protein binding,-
9914,37,6,0,2,28,26,23,0,15,0,10,0,"ATP2C2;ATPase, Ca++ transporting, type 2C, member 2",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0034220//ion transmembrane transport;GO:0055085//transmembrane transport;GO:0070588//calcium ion transmembrane transport;GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0005388//calcium-transporting ATPase activity;GO:0005515//protein binding;GO:0046872//metal ion binding,K01537//Purine metabolism
9915,0,0,0,17,38,9,26,0,101,83,0,0,ARNT2;aryl-hydrocarbon receptor nuclear translocator 2,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005667//transcription factor complex,"GO:0043066//negative regulation of apoptotic process;GO:0007417//central nervous system development;GO:0001666//response to hypoxia;GO:0006351//transcription, DNA-templated;GO:0007165//signal transduction;GO:0032355//response to estradiol;GO:0006355//regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0001701//in utero embryonic development;GO:0008284//positive regulation of cell proliferation",GO:0004871//signal transducer activity;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0046982//protein heterodimerization activity;GO:0017162//aryl hydrocarbon receptor binding,K15589//Pathways in cancer;Renal cell carcinoma;Transcriptional misregulation in cancer
9917,0,27,0,22,25,0,38,3,22,2,8,0,"FAM20B;family with sequence similarity 20, member B",GO:0000139//Golgi membrane;GO:0016021//integral component of membrane;GO:0005794//Golgi apparatus,GO:0016310//phosphorylation,"GO:0005524//ATP binding;GO:0016301//kinase activity;GO:0016773//phosphotransferase activity, alcohol group as acceptor",K00939//Metabolic pathways;Biosynthesis of secondary metabolites;Pyrimidine metabolism;Purine metabolism;K11447//Transcriptional misregulation in cancer
9918,0,2,2,0,24,9,0,0,18,0,0,0,"NCAPD2;non-SMC condensin I complex, subunit D2",GO:0000796//condensin complex;GO:0005730//nucleolus;GO:0005829//cytosol;GO:0000797//condensin core heterodimer;GO:0005634//nucleus;GO:0000793//condensed chromosome;GO:0045120//pronucleus;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0000228//nuclear chromosome,GO:0000278//mitotic cell cycle;GO:0007076//mitotic chromosome condensation,GO:0042393//histone binding;GO:0005515//protein binding,K06677//Cell cycle - yeast
9919,0,101,0,19,45,30,9,3,31,0,10,0,SEC16A;SEC16 homolog A (S. cerevisiae),GO:0005829//cytosol;GO:0000139//Golgi membrane;GO:0005794//Golgi apparatus;GO:0005789//endoplasmic reticulum membrane;GO:0005737//cytoplasm,GO:0007029//endoplasmic reticulum organization;GO:0015031//protein transport;GO:0048208//COPII vesicle coating;GO:0021762//substantia nigra development,-,-
9920,85,0,1,58,110,26,92,1,43,0,0,0,KBTBD11;kelch repeat and BTB (POZ) domain containing 11,-,-,-,-
9921,0,76,1,87,284,13,0,72,16,0,4,0,RNF10;ring finger protein 10,GO:0005737//cytoplasm;GO:0005634//nucleus,"GO:0031643//positive regulation of myelination;GO:0010626//negative regulation of Schwann cell proliferation;GO:0051865//protein autoubiquitination;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0006351//transcription, DNA-templated;GO:0045893//positive regulation of transcription, DNA-templated",GO:0044212//transcription regulatory region DNA binding;GO:0004842//ubiquitin-protein transferase activity;GO:0005515//protein binding;GO:0008270//zinc ion binding,K13346//Peroxisome
9922,55,2,0,17,29,39,39,89,72,166,9,0,IQSEC1;IQ motif and Sec7 domain 1,GO:0043231//intracellular membrane-bounded organelle;GO:0016020//membrane;GO:0030054//cell junction;GO:0005730//nucleolus;GO:0005802//trans-Golgi network,GO:0043547//positive regulation of GTPase activity;GO:0032012//regulation of ARF protein signal transduction;GO:0016192//vesicle-mediated transport;GO:0030036//actin cytoskeleton organization,GO:0005086//ARF guanyl-nucleotide exchange factor activity,K12495//Endocytosis
9923,54,53,0,1,15,0,19,54,66,0,4,0,ZBTB40;zinc finger and BTB domain containing 40,GO:0005634//nucleus,"GO:0030282//bone mineralization;GO:0006355//regulation of transcription, DNA-templated;GO:0006974//cellular response to DNA damage stimulus;GO:0006351//transcription, DNA-templated",GO:0046872//metal ion binding;GO:0003677//DNA binding,-
9924,0,18,0,9,19,25,35,0,24,0,4,0,PAN2;PAN2 poly(A) specific ribonuclease subunit,GO:0000932//cytoplasmic mRNA processing body;GO:0005634//nucleus;GO:0031251//PAN complex;GO:0005829//cytosol,"GO:0090503//RNA phosphodiester bond hydrolysis, exonucleolytic;GO:0000289//nuclear-transcribed mRNA poly(A) tail shortening;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process;GO:0000288//nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;GO:0010467//gene expression",GO:0004535//poly(A)-specific ribonuclease activity;GO:0005515//protein binding;GO:0000175//3'-5'-exoribonuclease activity;GO:0003676//nucleic acid binding,K12571//RNA degradation
9925,0,1,40,7,45,13,16,0,46,0,19,0,ZBTB5;zinc finger and BTB domain containing 5,GO:0005634//nucleus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated",GO:0003677//DNA binding;GO:0046872//metal ion binding,-
9926,0,0,0,12,20,39,20,29,38,0,0,0,LPGAT1;lysophosphatidylglycerol acyltransferase 1,GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0005737//cytoplasm;GO:0005789//endoplasmic reticulum membrane,GO:0036148//phosphatidylglycerol acyl-chain remodeling;GO:0046474//glycerophospholipid biosynthetic process;GO:0006644//phospholipid metabolic process;GO:0044281//small molecule metabolic process,"GO:0016746//transferase activity, transferring acyl groups",K13514//Glycerophospholipid metabolism
9927,0,58,0,30,176,33,0,104,55,134,5,0,MFN2;mitofusin 2,GO:0005739//mitochondrion;GO:0016021//integral component of membrane;GO:0005829//cytosol;GO:0005741//mitochondrial outer membrane;GO:0015630//microtubule cytoskeleton;GO:0031306//intrinsic component of mitochondrial outer membrane,GO:0001825//blastocyst formation;GO:0034497//protein localization to pre-autophagosomal structure;GO:0008053//mitochondrial fusion;GO:0008219//cell death;GO:0046580//negative regulation of Ras protein signal transduction;GO:0007050//cell cycle arrest;GO:0007006//mitochondrial membrane organization;GO:0006184//GTP catabolic process;GO:0007596//blood coagulation;GO:0006626//protein targeting to mitochondrion;GO:0048662//negative regulation of smooth muscle cell proliferation;GO:0048593//camera-type eye morphogenesis;GO:0051646//mitochondrion localization,GO:0031625//ubiquitin protein ligase binding;GO:0005515//protein binding;GO:0003924//GTPase activity;GO:0005525//GTP binding,-
9928,0,0,0,0,0,0,44,0,92,0,1,0,KIF14;kinesin family member 14,GO:0016020//membrane;GO:0005871//kinesin complex;GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005819//spindle;GO:0005874//microtubule,GO:0007018//microtubule-based movement;GO:0032487//regulation of Rap protein signal transduction;GO:0030705//cytoskeleton-dependent intracellular transport;GO:0034446//substrate adhesion-dependent cell spreading;GO:0006200//ATP catabolic process;GO:0030334//regulation of cell migration;GO:0030155//regulation of cell adhesion;GO:0045184//establishment of protein localization;GO:0033624//negative regulation of integrin activation;GO:0008152//metabolic process,GO:0005515//protein binding;GO:0008017//microtubule binding;GO:0003777//microtubule motor activity;GO:0016887//ATPase activity;GO:0030165//PDZ domain binding;GO:0005524//ATP binding,-
9929,1,0,0,9,0,8,55,29,24,0,17,310,JOSD1;Josephin domain containing 1,GO:0016020//membrane;GO:0005886//plasma membrane;GO:0005737//cytoplasm,GO:0006508//proteolysis,GO:0008242//omega peptidase activity,-
993,6,0,0,0,0,0,21,0,42,16,0,0,CDC25A;cell division cycle 25A,GO:0005654//nucleoplasm;GO:0005829//cytosol,GO:0007067//mitotic nuclear division;GO:0000082//G1/S transition of mitotic cell cycle;GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0009314//response to radiation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0034644//cellular response to UV,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,K06645//Progesterone-mediated oocyte maturation;Cell cycle
9931,7,0,0,7,100,73,53,0,78,0,6,0,HELZ;helicase with zinc finger,GO:0016020//membrane;GO:0005634//nucleus,GO:0008152//metabolic process,GO:0005524//ATP binding;GO:0004386//helicase activity;GO:0046872//metal ion binding;GO:0044822//poly(A) RNA binding,-
9933,0,0,0,4,25,6,0,0,58,0,0,0,KIAA0020;KIAA0020,GO:0005730//nucleolus;GO:0005783//endoplasmic reticulum,-,GO:0044822//poly(A) RNA binding,-
9934,0,0,0,0,0,24,0,0,15,0,0,0,"P2RY14;purinergic receptor P2Y, G-protein coupled, 14",GO:0005886//plasma membrane;GO:0016021//integral component of membrane,GO:0007186//G-protein coupled receptor signaling pathway;GO:0035589//G-protein coupled purinergic nucleotide receptor signaling pathway,GO:0045029//UDP-activated nucleotide receptor activity;GO:0045028//G-protein coupled purinergic nucleotide receptor activity,K04299//Neuroactive ligand-receptor interaction
9935,89,0,0,15,18,0,0,17,27,0,24,0,MAFB;v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B,GO:0005634//nucleus;GO:0005667//transcription factor complex,"GO:0033077//T cell differentiation in thymus;GO:0007423//sensory organ development;GO:0021571//rhombomere 5 development;GO:0006351//transcription, DNA-templated;GO:0007379//segment specification;GO:0045647//negative regulation of erythrocyte differentiation;GO:0035284//brain segmentation;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0048538//thymus development;GO:0042472//inner ear morphogenesis;GO:0007585//respiratory gaseous exchange",GO:0008134//transcription factor binding;GO:0043565//sequence-specific DNA binding;GO:0005515//protein binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
9937,0,33,0,1,53,0,0,65,57,0,0,18,DCLRE1A;DNA cross-link repair 1A,GO:0005634//nucleus,GO:0007067//mitotic nuclear division;GO:0006289//nucleotide-excision repair,-,-
9938,0,0,0,0,0,0,0,0,36,0,7,0,ARHGAP25;Rho GTPase activating protein 25,GO:0005829//cytosol,GO:0043547//positive regulation of GTPase activity;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0007264//small GTPase mediated signal transduction,GO:0005096//GTPase activator activity,K08878//Pathways in cancer;Chronic myeloid leukemia;K12490//Endocytosis;K07526//Axon guidance
9939,0,44,2,95,171,0,0,0,61,0,0,0,RBM8A;RNA binding motif protein 8A,GO:0005634//nucleus;GO:0005730//nucleolus;GO:0035145//exon-exon junction complex;GO:0016607//nuclear speck;GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0071013//catalytic step 2 spliceosome,"GO:0000398//mRNA splicing, via spliceosome;GO:0006366//transcription from RNA polymerase II promoter;GO:0008380//RNA splicing;GO:0010467//gene expression;GO:0006369//termination of RNA polymerase II transcription;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0006417//regulation of translation;GO:0006406//mRNA export from nucleus;GO:0031124//mRNA 3'-end processing;GO:0000184//nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0016071//mRNA metabolic process;GO:0016070//RNA metabolic process",GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0005515//protein binding;GO:0003729//mRNA binding;GO:0003723//RNA binding,K12876//RNA transport;mRNA surveillance pathway;Spliceosome
994,79,1,0,0,0,0,19,0,58,1,0,0,CDC25B;cell division cycle 25B,GO:0005737//cytoplasm;GO:0005813//centrosome;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0000922//spindle pole;GO:0005730//nucleolus;GO:0005829//cytosol,GO:0008284//positive regulation of cell proliferation;GO:0045931//positive regulation of mitotic cell cycle;GO:0032467//positive regulation of cytokinesis;GO:0007144//female meiosis I;GO:0045860//positive regulation of protein kinase activity;GO:0007067//mitotic nuclear division;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0001556//oocyte maturation;GO:0006468//protein phosphorylation;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding,K05866//Progesterone-mediated oocyte maturation;Cell cycle;MAPK signaling pathway
9940,209,38,151,100,55,42,28,109,53,32,15,365,DLEC1;deleted in lung and esophageal cancer 1,GO:0005737//cytoplasm,GO:0008285//negative regulation of cell proliferation,-,-
9941,0,0,0,13,10,0,0,5,36,0,8,0,"EXOG;endo/exonuclease (5'-3'), endonuclease G-like",GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane,"GO:0000737//DNA catabolic process, endonucleolytic",GO:0004519//endonuclease activity;GO:0046872//metal ion binding;GO:0003676//nucleic acid binding,-
9942,80,0,0,0,6,11,1,0,41,0,0,0,XYLB;xylulokinase homolog (H. influenzae),GO:0070062//extracellular vesicular exosome,GO:0005975//carbohydrate metabolic process;GO:0006091//generation of precursor metabolites and energy;GO:0005998//xylulose catabolic process;GO:0005997//xylulose metabolic process;GO:0042732//D-xylose metabolic process;GO:0046835//carbohydrate phosphorylation,GO:0005524//ATP binding;GO:0004856//xylulokinase activity,"K00854//Pentose and glucuronate interconversions;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Pyrimidine metabolism"
9943,26,0,0,0,75,0,0,0,61,0,0,0,OXSR1;oxidative stress responsive 1,GO:0005737//cytoplasm;GO:0070062//extracellular vesicular exosome,GO:0023014//signal transduction by phosphorylation;GO:1901017//negative regulation of potassium ion transmembrane transporter activity;GO:2000687//negative regulation of rubidium ion transmembrane transporter activity;GO:0006468//protein phosphorylation;GO:0006979//response to oxidative stress;GO:0018107//peptidyl-threonine phosphorylation;GO:1901380//negative regulation of potassium ion transmembrane transport;GO:0035556//intracellular signal transduction;GO:2000681//negative regulation of rubidium ion transport;GO:0071476//cellular hypotonic response,GO:0005524//ATP binding;GO:0000287//magnesium ion binding;GO:0004702//receptor signaling protein serine/threonine kinase activity;GO:0004674//protein serine/threonine kinase activity;GO:0005515//protein binding,-
9945,0,0,36,0,0,22,41,81,13,0,0,0,GFPT2;glutamine-fructose-6-phosphate transaminase 2,GO:0005829//cytosol,GO:0006048//UDP-N-acetylglucosamine biosynthetic process;GO:0006541//glutamine metabolic process;GO:0044267//cellular protein metabolic process;GO:0016051//carbohydrate biosynthetic process;GO:0006112//energy reserve metabolic process;GO:0006002//fructose 6-phosphate metabolic process;GO:0006488//dolichol-linked oligosaccharide biosynthetic process;GO:0018279//protein N-linked glycosylation via asparagine;GO:0043687//post-translational protein modification,GO:0004360//glutamine-fructose-6-phosphate transaminase (isomerizing) activity;GO:0030246//carbohydrate binding,"K00820//Biosynthesis of secondary metabolites;Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism"
9946,0,0,1,8,20,0,0,0,39,0,0,0,"CRYZL1;crystallin, zeta (quinone reductase)-like 1",GO:0005829//cytosol,GO:1901661//quinone metabolic process;GO:0055114//oxidation-reduction process,GO:0050661//NADP binding;GO:0003960//NADPH:quinone reductase activity;GO:0008270//zinc ion binding,-
9947,0,0,0,0,0,26,0,46,0,0,0,2,"MAGEC1;melanoma antigen family C, 1",-,-,GO:0005515//protein binding,K12464//Neurotrophin signaling pathway
9948,0,110,0,14,83,0,1,0,43,1,16,0,WDR1;WD repeat domain 1,GO:0002102//podosome;GO:0005737//cytoplasm;GO:0042995//cell projection;GO:0005829//cytosol;GO:0070062//extracellular vesicular exosome;GO:0005576//extracellular region;GO:0030054//cell junction,GO:0030168//platelet activation;GO:0002576//platelet degranulation;GO:0007605//sensory perception of sound;GO:0007596//blood coagulation,GO:0003779//actin binding,K12602//RNA degradation;K02084//Tuberculosis;Legionellosis;Small cell lung cancer;Huntington's disease;Parkinson's disease;p53 signaling pathway;Apoptosis;Alzheimer's disease;Amyotrophic lateral sclerosis (ALS)
9949,0,0,0,0,3,35,19,0,18,0,0,0,"AMMECR1;Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1",-,-,GO:0005515//protein binding,-
995,0,122,118,83,270,0,34,57,0,108,187,0,CDC25C;cell division cycle 25C,GO:0005829//cytosol;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0048471//perinuclear region of cytoplasm,GO:0006260//DNA replication;GO:0051726//regulation of cell cycle;GO:0000086//G2/M transition of mitotic cell cycle;GO:0000278//mitotic cell cycle;GO:0007283//spermatogenesis;GO:0008283//cell proliferation;GO:0000079//regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0035335//peptidyl-tyrosine dephosphorylation;GO:0007067//mitotic nuclear division;GO:0007088//regulation of mitosis;GO:0016032//viral process,GO:0004725//protein tyrosine phosphatase activity;GO:0005515//protein binding;GO:0019901//protein kinase binding;GO:0050699//WW domain binding,K05867//Oocyte meiosis;Cell cycle;Progesterone-mediated oocyte maturation
9950,0,32,0,38,113,8,22,0,15,0,7,0,GOLGA5;golgin A5,GO:0005794//Golgi apparatus;GO:0016020//membrane;GO:0016021//integral component of membrane;GO:0000139//Golgi membrane;GO:0005801//cis-Golgi network;GO:0031985//Golgi cisterna,GO:0048193//Golgi vesicle transport;GO:0007030//Golgi organization,GO:0042803//protein homodimerization activity;GO:0017137//Rab GTPase binding,K10352//Hypertrophic cardiomyopathy (HCM);Viral myocarditis;Regulation of actin cytoskeleton;Vascular smooth muscle contraction;Dilated cardiomyopathy;Cardiac muscle contraction;Tight junction;Salmonella infection
9951,0,0,0,0,0,0,61,0,0,0,6,0,HS3ST4;heparan sulfate (glucosamine) 3-O-sulfotransferase 4,GO:0016021//integral component of membrane;GO:0000139//Golgi membrane,GO:0030201//heparan sulfate proteoglycan metabolic process,GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity,-
9953,0,0,0,0,1,0,37,1,24,0,2,0,HS3ST3B1;heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1,GO:0000139//Golgi membrane;GO:0005887//integral component of plasma membrane,"GO:0005975//carbohydrate metabolic process;GO:0015015//heparan sulfate proteoglycan biosynthetic process, enzymatic modification;GO:0015012//heparan sulfate proteoglycan biosynthetic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process",GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity;GO:0033872//[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity,K07809//Glycosaminoglycan biosynthesis - heparan sulfate
9955,0,0,0,0,0,0,14,44,24,0,0,0,HS3ST3A1;heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0006024//glycosaminoglycan biosynthetic process,GO:0008146//sulfotransferase activity;GO:0033872//[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity,K07809//Glycosaminoglycan biosynthesis - heparan sulfate
9956,0,0,0,0,0,0,0,0,15,0,8,0,HS3ST2;heparan sulfate (glucosamine) 3-O-sulfotransferase 2,GO:0000139//Golgi membrane;GO:0016021//integral component of membrane,GO:0005975//carbohydrate metabolic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process;GO:0007623//circadian rhythm;GO:0006024//glycosaminoglycan biosynthetic process,GO:0033871//[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity;GO:0008146//sulfotransferase activity,K07808//Glycosaminoglycan biosynthesis - heparan sulfate
9957,0,0,0,0,0,0,17,0,10,0,0,0,HS3ST1;heparan sulfate (glucosamine) 3-O-sulfotransferase 1,GO:0016021//integral component of membrane;GO:0005796//Golgi lumen,GO:0005975//carbohydrate metabolic process;GO:0006024//glycosaminoglycan biosynthetic process;GO:0044281//small molecule metabolic process;GO:0030203//glycosaminoglycan metabolic process,GO:0008146//sulfotransferase activity;GO:0008467//[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity,K01024//Glycosaminoglycan biosynthesis - heparan sulfate
9958,192,1,0,7,20,1,5,0,74,0,6,255,USP15;ubiquitin specific peptidase 15,GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0030512//negative regulation of transforming growth factor beta receptor signaling pathway;GO:0006511//ubiquitin-dependent protein catabolic process;GO:0060389//pathway-restricted SMAD protein phosphorylation;GO:0035520//monoubiquitinated protein deubiquitination;GO:0016579//protein deubiquitination;GO:0007179//transforming growth factor beta receptor signaling pathway;GO:0030509//BMP signaling pathway,GO:0004221//ubiquitin thiolesterase activity;GO:0046332//SMAD binding;GO:0005160//transforming growth factor beta receptor binding;GO:0004197//cysteine-type endopeptidase activity;GO:0042802//identical protein binding;GO:0004843//ubiquitin-specific protease activity,-
996,0,54,1,9,54,47,0,0,1,0,0,0,CDC27;cell division cycle 27,GO:0005829//cytosol;GO:0005680//anaphase-promoting complex;GO:0005730//nucleolus;GO:0005876//spindle microtubule;GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005819//spindle;GO:0005813//centrosome;GO:0005737//cytoplasm,GO:0000278//mitotic cell cycle;GO:0008283//cell proliferation;GO:0007094//mitotic spindle assembly checkpoint;GO:0007091//metaphase/anaphase transition of mitotic cell cycle;GO:0051436//negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0051437//positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle;GO:0070979//protein K11-linked ubiquitination;GO:0031145//anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0051439//regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,GO:0019903//protein phosphatase binding;GO:0005515//protein binding,K03350//HTLV-I infection;Meiosis - yeast;Oocyte meiosis;Ubiquitin mediated proteolysis;Progesterone-mediated oocyte maturation;Cell cycle - yeast;Cell cycle
9960,0,74,36,23,144,19,19,0,3,0,0,0,USP3;ubiquitin specific peptidase 3,GO:0000790//nuclear chromatin,GO:0006511//ubiquitin-dependent protein catabolic process;GO:0000278//mitotic cell cycle;GO:0006281//DNA repair;GO:0016578//histone deubiquitination;GO:0031647//regulation of protein stability,GO:0004221//ubiquitin thiolesterase activity;GO:0004843//ubiquitin-specific protease activity;GO:0042393//histone binding;GO:0008270//zinc ion binding,-
9961,0,1,0,0,12,12,3,0,58,103,0,0,MVP;major vault protein,GO:0070062//extracellular vesicular exosome;GO:0030529//ribonucleoprotein complex;GO:0016020//membrane;GO:0005737//cytoplasm;GO:0005856//cytoskeleton;GO:0005643//nuclear pore;GO:0048471//perinuclear region of cytoplasm;GO:0005634//nucleus,GO:0038127//ERBB signaling pathway;GO:0031953//negative regulation of protein autophosphorylation;GO:0015031//protein transport;GO:0008283//cell proliferation;GO:0023057//negative regulation of signaling;GO:0061099//negative regulation of protein tyrosine kinase activity;GO:0051028//mRNA transport;GO:0072376//protein activation cascade,GO:0019903//protein phosphatase binding;GO:0005515//protein binding;GO:0019901//protein kinase binding,-
9962,79,0,0,8,17,9,26,0,56,116,0,0,"SLC23A2;solute carrier family 23 (ascorbic acid transporter), member 2",GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0016323//basolateral plasma membrane;GO:0016324//apical plasma membrane;GO:0005737//cytoplasm;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016020//membrane,GO:0006814//sodium ion transport;GO:0015851//nucleobase transport;GO:0070904//transepithelial L-ascorbic acid transport;GO:0019852//L-ascorbic acid metabolic process;GO:0035461//vitamin transmembrane transport;GO:0015993//molecular hydrogen transport;GO:0044281//small molecule metabolic process;GO:0006767//water-soluble vitamin metabolic process;GO:0006766//vitamin metabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0006979//response to oxidative stress,GO:0070890//sodium-dependent L-ascorbate transmembrane transporter activity;GO:0008523//sodium-dependent multivitamin transmembrane transporter activity;GO:0015205//nucleobase transmembrane transporter activity;GO:0008520//L-ascorbate:sodium symporter activity,K14611//Vitamin digestion and absorption
9963,0,0,0,26,1,27,10,0,47,0,0,0,"SLC23A1;solute carrier family 23 (ascorbic acid transporter), member 1",GO:0005737//cytoplasm;GO:0016324//apical plasma membrane;GO:0070062//extracellular vesicular exosome;GO:0005886//plasma membrane;GO:0016020//membrane;GO:0005903//brush border;GO:0005887//integral component of plasma membrane;GO:0009925//basal plasma membrane;GO:0043229//intracellular organelle,GO:0070904//transepithelial L-ascorbic acid transport;GO:0019852//L-ascorbic acid metabolic process;GO:0035461//vitamin transmembrane transport;GO:0006767//water-soluble vitamin metabolic process;GO:0044281//small molecule metabolic process;GO:0009636//response to toxic substance;GO:0015851//nucleobase transport;GO:0006814//sodium ion transport;GO:0070837//dehydroascorbic acid transport;GO:0007420//brain development;GO:0035725//sodium ion transmembrane transport;GO:0006766//vitamin metabolic process;GO:0006139//nucleobase-containing compound metabolic process;GO:0030324//lung development,GO:0015081//sodium ion transmembrane transporter activity;GO:0008520//L-ascorbate:sodium symporter activity;GO:0033300//dehydroascorbic acid transporter activity;GO:0015205//nucleobase transmembrane transporter activity;GO:0070890//sodium-dependent L-ascorbate transmembrane transporter activity;GO:0005515//protein binding,K14611//Vitamin digestion and absorption
9965,0,0,0,0,0,32,0,0,15,0,0,0,FGF19;fibroblast growth factor 19,GO:0005576//extracellular region,GO:0046326//positive regulation of glucose import;GO:0070374//positive regulation of ERK1 and ERK2 cascade;GO:0038095//Fc-epsilon receptor signaling pathway;GO:0048015//phosphatidylinositol-mediated signaling;GO:0008286//insulin receptor signaling pathway;GO:0046330//positive regulation of JNK cascade;GO:0001755//neural crest cell migration;GO:0007399//nervous system development;GO:0008284//positive regulation of cell proliferation;GO:0045087//innate immune response;GO:0048011//neurotrophin TRK receptor signaling pathway;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0070858//negative regulation of bile acid biosynthetic process;GO:0007507//heart development;GO:0008543//fibroblast growth factor receptor signaling pathway,GO:0005515//protein binding;GO:0005104//fibroblast growth factor receptor binding;GO:0008083//growth factor activity,K04358//Melanoma;Regulation of actin cytoskeleton;Pathways in cancer;MAPK signaling pathway
9966,0,0,0,0,9,0,10,0,0,0,0,0,"TNFSF15;tumor necrosis factor (ligand) superfamily, member 15",GO:0005887//integral component of plasma membrane;GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0005615//extracellular space,GO:0007165//signal transduction;GO:0007250//activation of NF-kappaB-inducing kinase activity;GO:0042107//cytokine metabolic process;GO:0050715//positive regulation of cytokine secretion;GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006955//immune response,GO:0005123//death receptor binding;GO:0005102//receptor binding;GO:0005164//tumor necrosis factor receptor binding;GO:0005125//cytokine activity,K05478//Cytokine-cytokine receptor interaction
9967,0,150,1,95,371,78,6,22,37,0,0,0,THRAP3;thyroid hormone receptor associated protein 3,GO:0016592//mediator complex;GO:0005634//nucleus;GO:0035145//exon-exon junction complex;GO:0005730//nucleolus,"GO:0000956//nuclear-transcribed mRNA catabolic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0000381//regulation of alternative mRNA splicing, via spliceosome;GO:0048026//positive regulation of mRNA splicing, via spliceosome;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0048255//mRNA stabilization;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0030521//androgen receptor signaling pathway;GO:0030518//intracellular steroid hormone receptor signaling pathway",GO:0051219//phosphoprotein binding;GO:0042809//vitamin D receptor binding;GO:0044822//poly(A) RNA binding;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0003712//transcription cofactor activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0003713//transcription coactivator activity;GO:0046966//thyroid hormone receptor binding;GO:0005524//ATP binding;GO:0004872//receptor activity,-
9968,99,0,1,6,8,2,54,47,69,0,27,0,MED12;mediator complex subunit 12,GO:0016020//membrane;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0005654//nucleoplasm,"GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0060070//canonical Wnt signaling pathway;GO:0019827//stem cell maintenance;GO:0060071//Wnt signaling pathway, planar cell polarity pathway;GO:0014044//Schwann cell development;GO:0010467//gene expression;GO:0014003//oligodendrocyte development;GO:0045893//positive regulation of transcription, DNA-templated;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0030521//androgen receptor signaling pathway;GO:0001843//neural tube closure;GO:0007507//heart development;GO:0030178//negative regulation of Wnt signaling pathway;GO:0090245//axis elongation involved in somitogenesis;GO:0030518//intracellular steroid hormone receptor signaling pathway",GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0019904//protein domain specific binding;GO:0008013//beta-catenin binding;GO:0004872//receptor activity;GO:0003682//chromatin binding;GO:0046966//thyroid hormone receptor binding;GO:0003713//transcription coactivator activity;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0008022//protein C-terminus binding;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0003712//transcription cofactor activity;GO:0001104//RNA polymerase II transcription cofactor activity;GO:0005515//protein binding;GO:0042809//vitamin D receptor binding,-
9969,0,53,7,136,350,57,0,0,37,35,16,0,MED13;mediator complex subunit 13,GO:0005654//nucleoplasm;GO:0016592//mediator complex;GO:0005634//nucleus;GO:0016020//membrane,"GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0045893//positive regulation of transcription, DNA-templated;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0030521//androgen receptor signaling pathway;GO:0030518//intracellular steroid hormone receptor signaling pathway;GO:0010467//gene expression",GO:0004872//receptor activity;GO:0003713//transcription coactivator activity;GO:0003712//transcription cofactor activity;GO:0046966//thyroid hormone receptor binding;GO:0030374//ligand-dependent nuclear receptor transcription coactivator activity;GO:0042809//vitamin D receptor binding;GO:0001104//RNA polymerase II transcription cofactor activity,-
997,0,20,0,0,8,0,0,0,13,0,16,0,CDC34;cell division cycle 34,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,GO:0070848//response to growth factor;GO:0016567//protein ubiquitination;GO:0070936//protein K48-linked ubiquitination;GO:0000209//protein polyubiquitination;GO:0090261//positive regulation of inclusion body assembly;GO:0006270//DNA replication initiation;GO:0043525//positive regulation of neuron apoptotic process;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0043951//negative regulation of cAMP-mediated signaling;GO:0006464//cellular protein modification process;GO:0000082//G1/S transition of mitotic cell cycle,GO:0005524//ATP binding;GO:0016881//acid-amino acid ligase activity;GO:0005515//protein binding;GO:0004842//ubiquitin-protein transferase activity,K02207//Herpes simplex infection;Ubiquitin mediated proteolysis
9970,0,0,54,72,67,12,77,0,51,2,88,0,"NR1I3;nuclear receptor subfamily 1, group I, member 3",GO:0005829//cytosol;GO:0005730//nucleolus;GO:0005654//nucleoplasm;GO:0005634//nucleus;GO:0005856//cytoskeleton;GO:0005737//cytoplasm,"GO:0010467//gene expression;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0007165//signal transduction;GO:0030522//intracellular receptor signaling pathway;GO:0030521//androgen receptor signaling pathway;GO:0045944//positive regulation of transcription from RNA polymerase II promoter",GO:0001228//RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription;GO:0003713//transcription coactivator activity;GO:0004887//thyroid hormone receptor activity;GO:0003677//DNA binding;GO:0004882//androgen receptor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0000977//RNA polymerase II regulatory region sequence-specific DNA binding;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,-
9971,49,0,0,0,0,0,0,0,17,0,0,0,"NR1H4;nuclear receptor subfamily 1, group H, member 4",GO:0005654//nucleoplasm;GO:0005719//nuclear euchromatin,GO:0007165//signal transduction;GO:0038185//intracellular bile acid receptor signaling pathway;GO:0070858//negative regulation of bile acid biosynthetic process;GO:0001080//nitrogen catabolite activation of transcription from RNA polymerase II promoter;GO:0045944//positive regulation of transcription from RNA polymerase II promoter;GO:0070857//regulation of bile acid biosynthetic process;GO:0030522//intracellular receptor signaling pathway;GO:0043401//steroid hormone mediated signaling pathway;GO:0034255//regulation of urea metabolic process;GO:0071229//cellular response to acid chemical;GO:0090181//regulation of cholesterol metabolic process;GO:0048565//digestive tract development;GO:2001250//positive regulation of ammonia assimilation cycle;GO:0009749//response to glucose;GO:0010467//gene expression;GO:0006109//regulation of carbohydrate metabolic process;GO:0000122//negative regulation of transcription from RNA polymerase II promoter;GO:0008206//bile acid metabolic process;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0032496//response to lipopolysaccharide,GO:0000980//RNA polymerase II distal enhancer sequence-specific DNA binding;GO:0038181//bile acid receptor activity;GO:0003714//transcription corepressor activity;GO:1902122//chenodeoxycholic acid binding;GO:0046965//retinoid X receptor binding;GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0003713//transcription coactivator activity;GO:0016922//ligand-dependent nuclear receptor binding;GO:0043565//sequence-specific DNA binding;GO:0004887//thyroid hormone receptor activity;GO:0042277//peptide binding;GO:0001190//RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription;GO:0032052//bile acid binding;GO:0003705//RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity;GO:0003700//sequence-specific DNA binding transcription factor activity;GO:0003707//steroid hormone receptor activity,K08537//Bile secretion
9972,111,0,0,12,33,0,20,66,42,36,0,0,NUP153;nucleoporin 153kDa,GO:0005737//cytoplasm;GO:0005654//nucleoplasm;GO:0031965//nuclear membrane;GO:0042405//nuclear inclusion body;GO:0005730//nucleolus;GO:0034399//nuclear periphery;GO:0005643//nuclear pore;GO:0044615//nuclear pore nuclear basket,GO:0044281//small molecule metabolic process;GO:0051292//nuclear pore complex assembly;GO:0075732//viral penetration into host nucleus;GO:0005975//carbohydrate metabolic process;GO:0016032//viral process;GO:0007077//mitotic nuclear envelope disassembly;GO:0051028//mRNA transport;GO:0010827//regulation of glucose transport;GO:0000278//mitotic cell cycle;GO:0055085//transmembrane transport;GO:0015031//protein transport;GO:0046832//negative regulation of RNA export from nucleus;GO:0019221//cytokine-mediated signaling pathway;GO:0015758//glucose transport;GO:0046718//viral entry into host cell,GO:0005215//transporter activity;GO:0005515//protein binding;GO:0005487//nucleocytoplasmic transporter activity;GO:0017056//structural constituent of nuclear pore;GO:0008270//zinc ion binding;GO:0043495//protein anchor;GO:0042802//identical protein binding;GO:0003677//DNA binding,K14296//RNA transport
9973,0,0,0,0,2,0,14,1,0,0,8,310,CCS;copper chaperone for superoxide dismutase,GO:0005829//cytosol;GO:0005737//cytoplasm;GO:0005634//nucleus,GO:0035434//copper ion transmembrane transport;GO:0055114//oxidation-reduction process;GO:0051353//positive regulation of oxidoreductase activity;GO:0015680//intracellular copper ion transport;GO:0006801//superoxide metabolic process;GO:0019430//removal of superoxide radicals,GO:0005515//protein binding;GO:0008270//zinc ion binding;GO:0015035//protein disulfide oxidoreductase activity;GO:0005375//copper ion transmembrane transporter activity;GO:0004784//superoxide dismutase activity;GO:0005507//copper ion binding,K04569//Amyotrophic lateral sclerosis (ALS)
9975,0,12,0,35,244,0,37,0,13,0,0,0,"NR1D2;nuclear receptor subfamily 1, group D, member 2",GO:0005634//nucleus;GO:0005654//nucleoplasm;GO:0005730//nucleolus,"GO:0010467//gene expression;GO:0019216//regulation of lipid metabolic process;GO:0045892//negative regulation of transcription, DNA-templated;GO:0043401//steroid hormone mediated signaling pathway;GO:0006367//transcription initiation from RNA polymerase II promoter;GO:0050727//regulation of inflammatory response;GO:0042752//regulation of circadian rhythm;GO:0006355//regulation of transcription, DNA-templated;GO:2001014//regulation of skeletal muscle cell differentiation;GO:0048511//rhythmic process;GO:0055088//lipid homeostasis;GO:0045893//positive regulation of transcription, DNA-templated;GO:2000505//regulation of energy homeostasis;GO:0030522//intracellular receptor signaling pathway",GO:0003707//steroid hormone receptor activity;GO:0008270//zinc ion binding;GO:0001046//core promoter sequence-specific DNA binding;GO:0004879//ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity;GO:0005515//protein binding,-
9976,0,0,0,0,0,0,4,0,57,0,0,0,"CLEC2B;C-type lectin domain family 2, member B",GO:0005887//integral component of plasma membrane,-,GO:0030246//carbohydrate binding,-
9978,0,0,1,1,38,0,0,0,9,0,0,0,"RBX1;ring-box 1, E3 ubiquitin protein ligase",GO:0031463//Cul3-RING ubiquitin ligase complex;GO:0031462//Cul2-RING ubiquitin ligase complex;GO:0031464//Cul4A-RING E3 ubiquitin ligase complex;GO:0031467//Cul7-RING ubiquitin ligase complex;GO:0005654//nucleoplasm;GO:0005829//cytosol;GO:0031466//Cul5-RING ubiquitin ligase complex;GO:0031465//Cul4B-RING E3 ubiquitin ligase complex;GO:0030891//VCB complex;GO:0019005//SCF ubiquitin ligase complex;GO:0031461//cullin-RING ubiquitin ligase complex,GO:0031146//SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0006513//protein monoubiquitination;GO:0016567//protein ubiquitination;GO:0045116//protein neddylation;GO:0016032//viral process;GO:0007219//Notch signaling pathway;GO:0071456//cellular response to hypoxia;GO:0006281//DNA repair;GO:0061418//regulation of transcription from RNA polymerase II promoter in response to hypoxia;GO:0043161//proteasome-mediated ubiquitin-dependent protein catabolic process,GO:0004842//ubiquitin-protein transferase activity;GO:0019788//NEDD8 ligase activity;GO:0005515//protein binding;GO:0031625//ubiquitin protein ligase binding;GO:0008270//zinc ion binding;GO:0032403//protein complex binding,K03868//Cell cycle - yeast;Renal cell carcinoma;Cell cycle;Protein processing in endoplasmic reticulum;Wnt signaling pathway;Oocyte meiosis;Circadian rhythm - mammal;Ubiquitin mediated proteolysis;TGF-beta signaling pathway;Pathways in cancer;Nucleotide excision repair
998,0,194,2,169,544,0,42,83,9,288,11,0,CDC42;cell division cycle 42,GO:0005829//cytosol;GO:0031256//leading edge membrane;GO:0005815//microtubule organizing center;GO:0005886//plasma membrane;GO:0045177//apical part of cell;GO:0043025//neuronal cell body;GO:0030141//secretory granule;GO:0005925//focal adhesion;GO:0030496//midbody;GO:0016020//membrane;GO:0000139//Golgi membrane;GO:0051233//spindle midzone;GO:0043005//neuron projection;GO:0070062//extracellular vesicular exosome;GO:0030175//filopodium;GO:0072686//mitotic spindle;GO:0005737//cytoplasm;GO:0005911//cell-cell junction,GO:0042692//muscle cell differentiation;GO:0021762//substantia nigra development;GO:0045859//regulation of protein kinase activity;GO:0051017//actin filament bundle assembly;GO:0048554//positive regulation of metalloenzyme activity;GO:0043497//regulation of protein heterodimerization activity;GO:0003161//cardiac conduction system development;GO:0051647//nucleus localization;GO:0035088//establishment or maintenance of apical/basal cell polarity;GO:0032467//positive regulation of cytokinesis;GO:0033138//positive regulation of peptidyl-serine phosphorylation;GO:0007030//Golgi organization;GO:0051489//regulation of filopodium assembly;GO:0031424//keratinization;GO:0043552//positive regulation of phosphatidylinositol 3-kinase activity;GO:0031274//positive regulation of pseudopodium assembly;GO:0042176//regulation of protein catabolic process;GO:0045740//positive regulation of DNA replication;GO:0034613//cellular protein localization;GO:0051988//regulation of attachment of spindle microtubules to kinetochore;GO:0007088//regulation of mitosis;GO:0071338//positive regulation of hair follicle cell proliferation;GO:0038096//Fc-gamma receptor signaling pathway involved in phagocytosis;GO:0034332//adherens junction organization;GO:0031295//T cell costimulation;GO:0031069//hair follicle morphogenesis;GO:0051149//positive regulation of muscle cell differentiation;GO:0051056//regulation of small GTPase mediated signal transduction;GO:0031647//regulation of protein stability;GO:0060047//heart contraction;GO:0007163//establishment or maintenance of cell polarity;GO:0007411//axon guidance;GO:0042059//negative regulation of epidermal growth factor receptor signaling pathway;GO:0006184//GTP catabolic process;GO:0060661//submandibular salivary gland formation;GO:0060070//canonical Wnt signaling pathway;GO:0030036//actin cytoskeleton organization;GO:1900026//positive regulation of substrate adhesion-dependent cell spreading;GO:0035264//multicellular organism growth;GO:0072384//organelle transport along microtubule;GO:0048664//neuron fate determination;GO:0046847//filopodium assembly;GO:0007173//epidermal growth factor receptor signaling pathway;GO:0003334//keratinocyte development;GO:0051835//positive regulation of synapse structural plasticity;GO:0090316//positive regulation of intracellular protein transport;GO:0007596//blood coagulation;GO:0090136//epithelial cell-cell adhesion;GO:0060789//hair follicle placode formation;GO:0007264//small GTPase mediated signal transduction;GO:0002040//sprouting angiogenesis;GO:0036336//dendritic cell migration;GO:0010629//negative regulation of gene expression;GO:0045087//innate immune response;GO:0046330//positive regulation of JNK cascade;GO:0010628//positive regulation of gene expression;GO:0031333//negative regulation of protein complex assembly;GO:0090135//actin filament branching;GO:0030225//macrophage differentiation;GO:0060684//epithelial-mesenchymal cell signaling;GO:0007097//nuclear migration;GO:0051683//establishment of Golgi localization;GO:0043525//positive regulation of neuron apoptotic process,GO:0034191//apolipoprotein A-I receptor binding;GO:0019901//protein kinase binding;GO:0042802//identical protein binding;GO:0031435//mitogen-activated protein kinase kinase kinase binding;GO:0005525//GTP binding;GO:0005515//protein binding;GO:0030742//GTP-dependent protein binding;GO:0031996//thioesterase binding;GO:0003924//GTPase activity,K04393//Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Shigellosis;Tight junction;Bacterial invasion of epithelial cells;Pathogenic Escherichia coli infection;VEGF signaling pathway;Focal adhesion;Regulation of actin cytoskeleton;Neurotrophin signaling pathway;Chemokine signaling pathway;Pathways in cancer;GnRH signaling pathway;Axon guidance;MAPK signaling pathway - yeast;Salmonella infection;Pancreatic cancer;Endocytosis;Adherens junction;Epithelial cell signaling in Helicobacter pylori infection;Renal cell carcinoma;T cell receptor signaling pathway;MAPK signaling pathway
9980,299,84,0,34,216,21,73,55,81,0,3,0,DOPEY2;dopey family member 2,GO:0000139//Golgi membrane;GO:0070062//extracellular vesicular exosome,GO:0050890//cognition;GO:0007029//endoplasmic reticulum organization;GO:0007275//multicellular organismal development;GO:0015031//protein transport;GO:0006895//Golgi to endosome transport,-,K11447//Transcriptional misregulation in cancer;K01875//Metabolic pathways;Aminoacyl-tRNA biosynthesis;Biotin metabolism;Arginine and proline metabolism;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
9982,0,0,0,0,0,0,0,0,1,0,0,0,FGFBP1;fibroblast growth factor binding protein 1,GO:0005886//plasma membrane;GO:0005615//extracellular space;GO:0009986//cell surface,GO:0008285//negative regulation of cell proliferation;GO:0007165//signal transduction;GO:0008284//positive regulation of cell proliferation;GO:0045743//positive regulation of fibroblast growth factor receptor signaling pathway;GO:0007267//cell-cell signaling,GO:0008201//heparin binding;GO:0005515//protein binding;GO:0017134//fibroblast growth factor binding,-
9984,0,0,0,10,50,23,12,0,14,0,6,0,THOC1;THO complex 1,GO:0000445//THO complex part of transcription export complex;GO:0016363//nuclear matrix;GO:0005634//nucleus;GO:0016607//nuclear speck;GO:0000346//transcription export complex;GO:0045171//intercellular bridge;GO:0005730//nucleolus;GO:0005737//cytoplasm,"GO:0032786//positive regulation of DNA-templated transcription, elongation;GO:2000002//negative regulation of DNA damage checkpoint;GO:0007165//signal transduction;GO:0048297//negative regulation of isotype switching to IgA isotypes;GO:0031297//replication fork processing;GO:0006396//RNA processing;GO:0006406//mRNA export from nucleus;GO:0046784//viral mRNA export from host cell nucleus;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0000018//regulation of DNA recombination;GO:0006351//transcription, DNA-templated;GO:0006915//apoptotic process;GO:0032784//regulation of DNA-templated transcription, elongation",GO:0003723//RNA binding;GO:0003677//DNA binding;GO:0005515//protein binding,K12878//RNA transport;Spliceosome
9985,0,0,0,0,13,0,0,3,9,0,10,2,REC8;REC8 meiotic recombination protein,GO:0034991//nuclear meiotic cohesin complex;GO:0000800//lateral element;GO:0005634//nucleus;GO:0000778//condensed nuclear chromosome kinetochore;GO:0001673//male germ cell nucleus,GO:0072520//seminiferous tubule development;GO:0000724//double-strand break repair via homologous recombination;GO:0009566//fertilization;GO:0007283//spermatogenesis;GO:0007131//reciprocal meiotic recombination;GO:0007126//meiotic nuclear division;GO:0001556//oocyte maturation;GO:0030999//linear element assembly;GO:0007062//sister chromatid cohesion;GO:0007141//male meiosis I;GO:0007286//spermatid development,-,K13054//Oocyte meiosis
9986,0,0,36,0,10,0,0,0,0,0,0,1,RCE1;Ras converting CAAX endopeptidase 1,GO:0005887//integral component of plasma membrane;GO:0005789//endoplasmic reticulum membrane;GO:0016020//membrane,GO:0071586//CAAX-box protein processing;GO:0006508//proteolysis,GO:0004197//cysteine-type endopeptidase activity;GO:0004222//metalloendopeptidase activity,K08658//Terpenoid backbone biosynthesis
9987,0,58,2,37,150,0,0,0,58,34,19,0,HNRNPDL;heterogeneous nuclear ribonucleoprotein D-like,GO:0005634//nucleus;GO:0005737//cytoplasm;GO:0005681//spliceosomal complex;GO:0070062//extracellular vesicular exosome;GO:0005730//nucleolus,"GO:0006355//regulation of transcription, DNA-templated;GO:0006351//transcription, DNA-templated;GO:0010468//regulation of gene expression;GO:0006396//RNA processing",GO:0003677//DNA binding;GO:0034046//poly(G) binding;GO:0003697//single-stranded DNA binding;GO:0000166//nucleotide binding;GO:0044822//poly(A) RNA binding;GO:0008143//poly(A) binding;GO:0003690//double-stranded DNA binding,-
9988,3,1,1,39,93,9,10,63,52,189,0,0,DMTF1;cyclin D binding myb-like transcription factor 1,GO:0005737//cytoplasm;GO:0005634//nucleus;GO:0005730//nucleolus,"GO:0006351//transcription, DNA-templated;GO:0007049//cell cycle;GO:0006355//regulation of transcription, DNA-templated",GO:0003682//chromatin binding;GO:0003677//DNA binding;GO:0003700//sequence-specific DNA binding transcription factor activity,-
9989,76,0,1,1,59,35,33,0,24,0,0,0,"PPP4R1;protein phosphatase 4, regulatory subunit 1",GO:0030289//protein phosphatase 4 complex,GO:0016311//dephosphorylation;GO:0006468//protein phosphorylation;GO:0007165//signal transduction;GO:0050790//regulation of catalytic activity,GO:0005515//protein binding;GO:0030362//protein phosphatase type 4 regulator activity;GO:0004721//phosphoprotein phosphatase activity,-
999,96,0,0,2,53,27,40,0,96,171,0,0,"CDH1;cadherin 1, type 1, E-cadherin (epithelial)",GO:0016021//integral component of membrane;GO:0009898//cytoplasmic side of plasma membrane;GO:0030054//cell junction;GO:0005886//plasma membrane;GO:0005802//trans-Golgi network;GO:0045177//apical part of cell;GO:0005913//cell-cell adherens junction;GO:0016235//aggresome;GO:0033268//node of Ranvier;GO:0015629//actin cytoskeleton;GO:0048471//perinuclear region of cytoplasm;GO:0016342//catenin complex;GO:0043296//apical junction complex;GO:0009986//cell surface;GO:0005576//extracellular region;GO:0005768//endosome;GO:0070062//extracellular vesicular exosome;GO:0016328//lateral plasma membrane;GO:0043679//axon terminus;GO:0005737//cytoplasm;GO:0016323//basolateral plasma membrane;GO:0005925//focal adhesion;GO:0043220//Schmidt-Lanterman incisure;GO:0043219//lateral loop,"GO:0007416//synapse assembly;GO:0050776//regulation of immune response;GO:0022408//negative regulation of cell-cell adhesion;GO:0060662//salivary gland cavitation;GO:0019538//protein metabolic process;GO:0043281//regulation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0009636//response to toxic substance;GO:0060693//regulation of branching involved in salivary gland morphogenesis;GO:0003382//epithelial cell morphogenesis;GO:0090090//negative regulation of canonical Wnt signaling pathway;GO:0060576//intestinal epithelial cell development;GO:0071285//cellular response to lithium ion;GO:0071681//cellular response to indole-3-methanol;GO:0016337//single organismal cell-cell adhesion;GO:0022617//extracellular matrix disassembly;GO:2000008//regulation of protein localization to cell surface;GO:2001222//regulation of neuron migration;GO:0042993//positive regulation of transcription factor import into nucleus;GO:0001829//trophectodermal cell differentiation;GO:0070830//tight junction assembly;GO:0006921//cellular component disassembly involved in execution phase of apoptosis;GO:0050680//negative regulation of epithelial cell proliferation;GO:0006915//apoptotic process;GO:0090002//establishment of protein localization to plasma membrane;GO:0090102//cochlea development;GO:0016339//calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007605//sensory perception of sound;GO:0042493//response to drug;GO:0051260//protein homooligomerization;GO:0045893//positive regulation of transcription, DNA-templated;GO:0071230//cellular response to amino acid stimulus;GO:0030198//extracellular matrix organization;GO:0031175//neuron projection development;GO:0034332//adherens junction organization;GO:0045216//cell-cell junction organization;GO:0021983//pituitary gland development;GO:0007156//homophilic cell adhesion via plasma membrane adhesion molecules;GO:0033561//regulation of water loss via skin;GO:0072659//protein localization to plasma membrane;GO:0034329//cell junction assembly",GO:0008013//beta-catenin binding;GO:0019904//protein domain specific binding;GO:0001948//glycoprotein binding;GO:0045295//gamma-catenin binding;GO:0019903//protein phosphatase binding;GO:0030506//ankyrin binding;GO:0050839//cell adhesion molecule binding;GO:0032794//GTPase activating protein binding;GO:0005515//protein binding;GO:0005509//calcium ion binding,K05689//Pathways in cancer;Bacterial invasion of epithelial cells;Endometrial cancer;Cell adhesion molecules (CAMs);Melanoma;Pathogenic Escherichia coli infection;Bladder cancer;Adherens junction;Thyroid cancer
9990,288,0,12,8,43,0,53,177,54,0,0,0,"SLC12A6;solute carrier family 12 (potassium/chloride transporter), member 6",GO:0005886//plasma membrane;GO:0016021//integral component of membrane;GO:0016323//basolateral plasma membrane,GO:1902476//chloride transmembrane transport;GO:0010107//potassium ion import;GO:0071477//cellular hypotonic salinity response;GO:0006821//chloride transport;GO:0001525//angiogenesis;GO:0006813//potassium ion transport;GO:0035826//rubidium ion transport;GO:0006811//ion transport;GO:0071476//cellular hypotonic response;GO:0055085//transmembrane transport,GO:0015079//potassium ion transmembrane transporter activity;GO:0019901//protein kinase binding;GO:0035827//rubidium ion transmembrane transporter activity;GO:0015379//potassium:chloride symporter activity,K14427//GABAergic synapse
9991,0,2,13,96,336,74,16,68,52,0,15,0,PTBP3;polypyrimidine tract binding protein 3,GO:0005634//nucleus,GO:0009653//anatomical structure morphogenesis;GO:0033119//negative regulation of RNA splicing;GO:0043249//erythrocyte maturation;GO:0006397//mRNA processing;GO:0008380//RNA splicing;GO:0045595//regulation of cell differentiation,GO:0044822//poly(A) RNA binding;GO:0000166//nucleotide binding;GO:0003723//RNA binding,-
9992,0,0,0,14,6,0,0,0,0,0,0,0,"KCNE2;potassium voltage-gated channel, Isk-related family, member 2",GO:0008076//voltage-gated potassium channel complex;GO:0005764//lysosome;GO:0005886//plasma membrane;GO:0009986//cell surface,GO:0086011//membrane repolarization during action potential;GO:1902259//regulation of delayed rectifier potassium channel activity;GO:1901379//regulation of potassium ion transmembrane transport;GO:0034613//cellular protein localization;GO:1901979//regulation of inward rectifier potassium channel activity;GO:1901800//positive regulation of proteasomal protein catabolic process;GO:0086091//regulation of heart rate by cardiac conduction;GO:0060307//regulation of ventricular cardiac muscle cell membrane repolarization;GO:1902159//regulation of cyclic nucleotide-gated ion channel activity;GO:0007568//aging;GO:0060306//regulation of membrane repolarization;GO:0071805//potassium ion transmembrane transport;GO:0086009//membrane repolarization;GO:0071435//potassium ion export;GO:0035690//cellular response to drug;GO:0086005//ventricular cardiac muscle cell action potential;GO:0086002//cardiac muscle cell action potential involved in contraction;GO:0043586//tongue development;GO:0010107//potassium ion import,GO:0042803//protein homodimerization activity;GO:0044325//ion channel binding;GO:0015459//potassium channel regulator activity;GO:0005251//delayed rectifier potassium channel activity;GO:0005242//inward rectifier potassium channel activity;GO:1902282//voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization,K04896//Gastric acid secretion
9993,0,0,0,0,15,0,0,48,0,0,7,263,DGCR2;DiGeorge syndrome critical region gene 2,GO:0016021//integral component of membrane,GO:0007155//cell adhesion;GO:0009887//organ morphogenesis;GO:0050890//cognition,GO:0030246//carbohydrate binding,K01672//Bile secretion;Pancreatic secretion;Nitrogen metabolism;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Collecting duct acid secretion;K06560//Phagosome;Tuberculosis;K03068//Wnt signaling pathway
9994,0,0,0,8,41,0,1,0,73,0,0,0,CASP8AP2;caspase 8 associated protein 2,GO:0005739//mitochondrion;GO:0016605//PML body;GO:0005634//nucleus;GO:0005737//cytoplasm,"GO:0006919//activation of cysteine-type endopeptidase activity involved in apoptotic process;GO:0006355//regulation of transcription, DNA-templated;GO:0008625//extrinsic apoptotic signaling pathway via death domain receptors;GO:0007165//signal transduction;GO:0007049//cell cycle;GO:0006351//transcription, DNA-templated;GO:0097190//apoptotic signaling pathway;GO:0036337//Fas signaling pathway;GO:0071260//cellular response to mechanical stimulus",GO:0016505//peptidase activator activity involved in apoptotic process;GO:0003677//DNA binding;GO:0032184//SUMO polymer binding;GO:0005515//protein binding;GO:0003714//transcription corepressor activity;GO:0008656//cysteine-type endopeptidase activator activity involved in apoptotic process;GO:0005123//death receptor binding,K12893//Spliceosome;Herpes simplex infection;K14572//Ribosome biogenesis in eukaryotes
9997,0,66,0,27,65,0,62,57,9,0,190,0,SCO2;SCO2 cytochrome c oxidase assembly protein,GO:0005739//mitochondrion;GO:0005743//mitochondrial inner membrane;GO:0030016//myofibril;GO:0005730//nucleolus;GO:0005634//nucleus,GO:0014823//response to activity;GO:0001654//eye development;GO:0055114//oxidation-reduction process;GO:0006825//copper ion transport;GO:0008535//respiratory chain complex IV assembly;GO:0006878//cellular copper ion homeostasis;GO:0001701//in utero embryonic development;GO:0022904//respiratory electron transport chain;GO:0003012//muscle system process,GO:0005507//copper ion binding,-
A1BG-AS1,0,0,0,0,0,16,0,0,0,0,0,0,-,-,-,-,-
A2M-AS1,0,0,0,0,0,0,0,0,2,0,0,0,-,-,-,-,-
A2ML1-AS2,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
AADACL2-AS1,0,0,0,0,0,30,0,0,0,0,0,0,-,-,-,-,-
AATBC,5,0,7,5,17,12,0,1,9,196,60,1,-,-,-,-,-
ABCA9-AS1,1,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
ACAP2-IT1,0,0,0,0,0,0,0,34,0,0,0,0,-,-,-,-,-
ADAMTS9-AS1,0,0,0,0,0,17,27,0,45,0,5,0,-,-,-,-,-
ADAMTS9-AS2,70,0,0,0,13,45,10,0,230,0,13,0,-,-,-,-,-
ADGRA1-AS1,0,0,0,0,0,0,17,0,0,0,0,0,-,-,-,-,-
ADIRF-AS1,17,10322,3607,8331,15568,8,341,3460,548,2,5846,5,-,-,-,-,-
ADNP-AS1,0,13,36,5,0,0,0,213,0,0,10,0,-,-,-,-,-
ADORA2A-AS1,0,0,0,0,0,0,0,0,8,0,0,0,-,-,-,-,-
ADPGK-AS1,0,0,1,83,0,31,0,41,17,0,54,0,-,-,-,-,-
AGAP1-IT1,0,0,0,0,0,0,13,41,0,0,0,0,-,-,-,-,-
AGBL1-AS1,0,25,0,0,1,0,0,0,0,0,59,0,-,-,-,-,-
AKT3-IT1,0,0,0,0,0,0,0,0,0,0,3,0,-,-,-,-,-
ALG9-IT1,0,0,0,0,0,0,0,0,8,0,0,0,-,-,-,-,-
ALKBH3-AS1,0,0,27,30,17,0,0,0,0,0,7,0,-,-,-,-,-
ALMS1-IT1,69,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
AMMECR1-IT1,0,0,0,0,0,25,0,0,5,0,0,0,-,-,-,-,-
ANKRD33B-AS1,0,0,0,0,0,0,16,0,0,0,0,0,-,-,-,-,-
ANKRD34C-AS1,0,0,0,0,0,20,1,0,2,0,5,0,-,-,-,-,-
ANO1-AS2,0,0,0,0,0,0,0,0,0,0,8,0,-,-,-,-,-
AP4B1-AS1,0,0,0,0,0,0,0,0,2,0,0,0,-,-,-,-,-
APCDD1L-AS1,164,0,0,0,0,16,0,0,78,0,0,0,-,-,-,-,-
APOA1-AS,0,0,0,0,0,0,136,0,43,0,0,0,-,-,-,-,-
APTR,0,0,0,0,0,10,30,0,26,0,0,0,-,-,-,-,-
AQP4-AS1,0,0,0,0,0,0,21,0,56,0,0,0,-,-,-,-,-
ARAP1-AS1,0,110,138,91,144,0,56,605,105,3,464,1,-,-,-,-,-
ARAP1-AS2,0,125,67,48,86,0,112,145,103,0,272,0,-,-,-,-,-
ARF4-AS1,0,0,0,4,0,1,0,0,0,0,0,0,-,-,-,-,-
ARHGAP22-IT1,0,0,0,0,0,12,0,49,0,0,0,0,-,-,-,-,-
ARHGAP26-AS1,0,0,0,0,0,34,0,0,0,0,0,0,-,-,-,-,-
ARHGAP26-IT1,0,0,0,0,0,0,0,0,0,0,9,117,-,-,-,-,-
ARHGEF19-AS1,0,4,0,7,13,0,0,1,0,0,0,0,-,-,-,-,-
ARHGEF26-AS1,0,0,0,0,0,0,41,0,9,0,0,0,-,-,-,-,-
ARHGEF3-AS1,0,0,0,0,0,0,0,0,6,0,0,0,-,-,-,-,-
ARHGEF7-AS1,0,0,0,0,0,0,0,0,1,0,1,0,-,-,-,-,-
ARHGEF7-AS2,0,0,29,34,70,0,0,522,68,0,210,0,-,-,-,-,-
ARHGEF7-IT1,0,0,0,0,0,0,22,0,0,0,0,0,-,-,-,-,-
ARNTL2-AS1,0,0,0,0,0,0,8,0,9,0,0,0,-,-,-,-,-
ARPP21-AS1,0,0,0,0,0,0,0,0,0,124,0,0,-,-,-,-,-
ARSD-AS1,0,25,0,40,128,0,0,0,0,0,54,0,-,-,-,-,-
ASH1L-IT1,0,0,0,0,0,0,0,0,4,0,0,0,-,-,-,-,-
ASTN2-AS1,0,0,0,0,0,23,0,0,0,0,0,0,-,-,-,-,-
ATE1-AS1,0,0,0,0,0,0,0,50,20,0,0,0,-,-,-,-,-
ATP2B2-IT2,0,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
ATP6V0E2-AS1,1,437,256,236,1098,11,36,355,178,0,2623,3,-,-,-,-,-
ATXN8OS,0,0,0,0,16,16,0,0,0,0,0,0,-,-,-,-,-
AZIN1-AS1,0,0,37,0,7,0,11,0,57,95,17,0,-,-,-,-,-
B3GALT5-AS1,106,0,0,0,0,20,0,41,35,152,0,125,-,-,-,-,-
B4GALT1-AS1,0,0,0,0,0,10,0,0,8,0,0,0,-,-,-,-,-
BAALC-AS1,0,0,0,0,0,20,1,0,47,0,1,0,-,-,-,-,-
BACE2-IT1,0,0,0,0,0,14,0,68,0,0,0,0,-,-,-,-,-
BACH1-AS1,0,0,0,0,1,0,0,0,22,0,0,0,-,-,-,-,-
BACH1-IT2,49,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
BARX1-AS1,0,0,0,0,0,32,14,0,11,0,0,0,-,-,-,-,-
BBOX1-AS1,0,0,0,0,0,20,0,0,0,0,0,0,-,-,-,-,-
BCAR4,0,0,0,0,12,0,0,0,28,0,0,0,-,-,-,-,-
BCYRN1,0,40,0,12,30,39,40,0,57,3,57,0,-,-,-,-,-
BDNF-AS,0,0,0,0,0,21,22,0,39,0,0,0,-,-,-,-,-
BFSP2-AS1,0,0,0,0,0,20,0,0,0,0,0,0,-,-,-,-,-
BIRC6-AS1,0,340,278,420,803,15,63,0,0,0,207,0,-,-,-,-,-
BISPR,0,0,25,0,0,0,0,0,4,89,0,1,-,-,-,-,-
BMPR1B-AS1,55,0,0,16,0,0,0,0,0,0,0,0,-,-,-,-,-
BOK-AS1,0,0,0,0,0,0,17,2,15,0,0,0,-,-,-,-,-
BOLA3-AS1,0,459,383,1120,1723,0,56,1,57,0,809,0,-,-,-,-,-
BRWD1-IT1,0,0,0,0,0,30,0,0,3,0,0,0,-,-,-,-,-
BSN-AS2,0,0,0,0,0,12,0,0,0,0,0,0,-,-,-,-,-
BTBD9-AS1,0,0,0,0,0,0,0,0,13,0,0,0,-,-,-,-,-
BZRAP1-AS1,1,0,8,16,44,5,0,0,0,0,48,0,-,-,-,-,-
C10orf71-AS1,1,0,0,0,0,0,0,0,8,0,0,0,-,-,-,-,-
C15orf59-AS1,76,37,0,0,32,0,0,28,34,0,90,0,-,-,-,-,-
C1QTNF9B-AS1,0,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
C1RL-AS1,0,0,0,27,27,0,0,0,1,0,41,0,-,-,-,-,-
C20orf166-AS1,109,0,0,0,0,6,0,0,5,0,8,120,-,-,-,-,-
C21orf62-AS1,0,0,0,0,0,7,38,2,78,1,17,0,-,-,-,-,-
C3orf67-AS1,0,0,0,0,0,0,0,0,32,0,0,0,-,-,-,-,-
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MIR646HG,0,47,484,21,16,45,77,0,66,1,16,0,-,-,-,-,-
MIR663AHG,0,0,0,0,0,5,45,30,32,0,27,0,-,-,-,-,-
MIR7-3HG,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
MIR762HG,0,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
MIR9-3HG,0,0,35,0,1,28,12,4,117,100,316,123,-,-,-,-,-
MIR924HG,0,0,0,0,0,0,11,0,3,0,4,0,-,-,-,-,-
MIR99AHG,0,0,0,0,0,1,0,0,54,0,0,0,-,-,-,-,-
MIS18A-AS1,0,0,0,8,0,48,0,0,15,0,0,0,-,-,-,-,-
MKLN1-AS,0,0,0,1,0,0,18,0,0,0,8,0,-,-,-,-,-
MKNK1-AS1,0,0,0,0,0,0,7,0,0,0,0,0,-,-,-,-,-
MKX-AS1,0,0,0,0,0,0,0,0,16,0,0,0,-,-,-,-,-
MLIP-AS1,0,0,0,0,0,0,5,0,16,0,0,0,-,-,-,-,-
MLK7-AS1,0,0,0,0,0,0,0,0,0,0,8,0,-,-,-,-,-
MME-AS1,0,314,498,861,651,0,46,228,0,0,454,1,-,-,-,-,-
MMP24-AS1,0,0,0,0,19,2,0,0,0,0,0,0,-,-,-,-,-
MMP25-AS1,0,0,0,0,0,0,0,0,5,0,0,0,-,-,-,-,-
MORC2-AS1,0,127,93,141,379,0,19,372,90,1,431,180,-,-,-,-,-
MPRIP-AS1,0,0,15,0,3,0,0,0,0,0,0,0,-,-,-,-,-
MRGPRF-AS1,0,0,0,0,0,0,0,0,2,0,0,0,-,-,-,-,-
MRPL23-AS1,0,0,0,0,0,0,14,0,0,0,0,0,-,-,-,-,-
MRVI1-AS1,0,158,91,300,351,0,0,193,2,0,199,0,-,-,-,-,-
MSC-AS1,0,0,0,0,0,32,0,0,16,0,0,0,-,-,-,-,-
MTUS2-AS1,0,0,0,0,0,0,0,0,0,228,0,0,-,-,-,-,-
MTUS2-AS2,0,0,0,0,0,51,7,165,8,18,0,0,-,-,-,-,-
MYB-AS1,0,0,0,4,0,0,0,0,6,0,2,0,-,-,-,-,-
MYCBP2-AS1,0,380,126,490,476,2,0,0,34,0,166,0,-,-,-,-,-
MYCBP2-AS2,0,0,0,0,0,0,0,77,0,0,0,0,-,-,-,-,-
MYCNOS,0,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
MYCNUT,0,0,0,0,0,36,0,0,0,0,0,0,-,-,-,-,-
MYHAS,0,0,0,0,0,0,0,0,23,0,0,0,-,-,-,-,-
MYLK-AS1,0,51,0,85,87,0,0,0,21,0,52,0,-,-,-,-,-
MYO16-AS1,0,0,0,0,0,11,0,0,0,0,0,0,-,-,-,-,-
MZF1-AS1,0,0,0,23,47,0,6,40,34,0,93,0,-,-,-,-,-
NAALADL2-AS1,0,0,0,0,0,0,0,0,0,0,3,0,-,-,-,-,-
NADK2-AS1,0,0,0,0,0,11,0,0,0,0,0,0,-,-,-,-,-
NAGPA-AS1,0,0,0,0,0,0,0,6,0,0,0,0,-,-,-,-,-
NALT1,0,0,0,0,0,0,0,0,10,188,10,0,-,-,-,-,-
NAPA-AS1,0,342,344,261,568,0,22,182,50,0,691,0,-,-,-,-,-
NAV2-AS1,0,0,0,0,0,0,36,0,0,0,0,0,-,-,-,-,-
NAV2-AS3,10,0,0,0,0,0,40,132,0,0,0,0,-,-,-,-,-
NAV2-AS5,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
NAV2-IT1,0,0,0,0,0,0,11,0,0,0,0,0,-,-,-,-,-
NBR2,0,0,0,0,0,0,0,0,0,0,0,73,-,-,-,-,-
NCAM1-AS1,0,0,0,0,0,0,55,0,12,74,1,0,-,-,-,-,-
NCBP2-AS1,0,82,1,52,158,0,0,0,23,0,114,0,-,-,-,-,-
NCK1-AS1,0,0,0,0,0,0,0,0,18,0,0,0,-,-,-,-,-
NCOA7-AS1,0,0,0,0,0,0,0,0,8,0,0,0,-,-,-,-,-
NDUFA6-AS1,0,0,0,0,0,21,45,0,15,0,8,0,-,-,-,-,-
NDUFV2-AS1,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
NEAT1,3,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
NEBL-AS1,0,0,36,0,0,0,0,222,10,0,6,0,-,-,-,-,-
NFIA-AS1,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
NFYC-AS1,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
NIFK-AS1,0,0,0,0,0,0,0,0,0,0,0,2,-,-,-,-,-
NIPBL-AS1,0,0,0,0,0,12,2,0,33,0,0,0,-,-,-,-,-
NKILA,0,329,295,366,295,0,22,834,32,0,856,1,-,-,-,-,-
NM_001297645,97,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297647,0,0,0,0,0,0,0,0,0,0,3,0,-,-,-,-,-
NM_001297651,0,0,0,0,0,0,0,0,16,0,0,0,-,-,-,-,-
NM_001297652,0,0,0,0,0,3,0,0,0,0,0,0,-,-,-,-,-
NM_001297656,60,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297659,0,0,0,0,0,0,0,53,0,0,3,0,-,-,-,-,-
NM_001297664,0,42,0,62,164,17,0,0,10,0,64,0,-,-,-,-,-
NM_001297668,9,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297669,0,0,0,0,0,31,0,0,0,0,0,0,-,-,-,-,K08732//Pathways in cancer;Pancreatic cancer;Colorectal cancer
NM_001297703,0,0,0,0,0,0,0,0,0,0,15,0,-,-,-,-,-
NM_001297705,0,0,0,0,0,0,21,0,0,0,0,0,-,-,-,-,-
NM_001297732,0,0,0,0,0,0,11,0,0,0,0,0,-,-,-,-,K03217//Metabolic pathways;ABC transporters;Bacterial secretion system;Protein export;Biosynthesis of secondary metabolites;Starch and sucrose metabolism;Amino sugar and nucleotide sugar metabolism
NM_001297734,0,0,0,0,6,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297751,0,0,0,0,0,8,0,0,0,0,0,0,-,-,-,-,-
NM_001297753,0,0,18,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297754,0,0,0,1,1,0,0,9,0,187,0,0,-,-,-,-,-
NM_001297756,0,0,0,0,0,0,0,0,0,0,9,0,-,-,-,-,-
NM_001297766,0,0,13,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001297771,0,0,0,0,0,0,0,60,0,0,0,0,-,-,-,-,K12183//Endocytosis
NM_001297774,0,0,0,0,0,0,0,0,2,0,0,0,-,-,-,-,K15290//Synaptic vesicle cycle
NM_001297779,0,36,0,0,0,0,0,0,0,0,0,0,-,-,-,-,K06210//Nicotinate and nicotinamide metabolism;Metabolic pathways
NM_001300731,0,0,0,0,0,3,0,0,0,0,0,0,-,-,-,-,-
NM_001300750,143,0,0,0,0,0,32,0,0,0,0,0,-,-,-,-,-
NM_001300754,0,0,0,0,0,0,0,0,20,0,0,0,-,-,-,-,-
NM_001300755,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,K12603//RNA degradation
NM_001300759,0,0,0,0,8,0,0,0,0,0,0,0,-,-,-,-,-
NM_001300760,0,0,0,0,0,0,0,0,0,0,0,430,-,-,-,-,-
NM_001300784,0,0,22,0,0,0,0,0,0,0,0,0,-,-,-,-,K09580//Protein processing in endoplasmic reticulum
NM_001300801,0,0,0,0,0,0,0,0,0,112,0,1,-,-,-,-,K01106//Insulin signaling pathway;Metabolic pathways;Phosphatidylinositol signaling system;Inositol phosphate metabolism
NM_001300806,1,0,0,0,0,0,0,0,16,0,0,0,-,-,-,-,-
NM_001300821,0,0,1,9,34,0,0,0,0,0,0,0,-,-,-,-,K03258//RNA transport;mTOR signaling pathway
NM_001300836,0,0,30,24,13,0,0,104,0,0,15,0,-,-,-,-,K01109//Inositol phosphate metabolism;Metabolic pathways;Phosphatidylinositol signaling system
NM_001300845,0,0,0,0,0,0,0,25,0,0,0,0,-,-,-,-,-
NM_001300853,0,0,0,0,0,0,0,2,0,0,0,427,-,-,-,-,-
NM_001300865,0,0,0,0,0,0,0,0,0,22,0,0,-,-,-,-,K15304//HTLV-I infection
NM_001300881,0,0,0,0,0,24,0,0,0,0,0,0,-,-,-,-,K13353//Peroxisome
NM_001300883,0,0,0,1,0,0,0,0,16,0,2,0,-,-,-,-,-
NM_001300887,1,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,K12393//Lysosome
NM_001300888,27,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001300898,0,0,0,0,0,0,8,0,0,0,0,0,-,-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;Metabolic pathways;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
NM_001300900,0,0,0,0,0,24,0,0,0,0,0,315,-,-,-,-,-
NM_001300901,91,0,0,0,5,0,0,0,0,0,5,0,-,-,-,-,-
NM_001300902,0,0,0,0,6,0,0,0,9,0,0,0,-,-,-,-,K04006//Hematopoietic cell lineage;Viral myocarditis;Complement and coagulation cascades
NM_001300912,0,0,0,4,0,0,61,0,0,0,0,0,-,-,-,-,-
NM_001300921,0,0,0,0,0,0,0,0,0,313,0,0,-,-,-,-,-
NM_001300926,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,-
NM_001300949,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,-
NM_001300952,0,0,0,0,0,0,17,0,11,0,8,287,-,-,-,-,K07526//Axon guidance
NM_001300958,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
NM_001300959,0,0,0,0,0,0,0,2,0,0,0,0,-,-,-,-,K16063//Small cell lung cancer;Ubiquitin mediated proteolysis;Jak-STAT signaling pathway;Pathways in cancer;K16065//Ubiquitin mediated proteolysis;NF-kappa B signaling pathway;Jak-STAT signaling pathway;K04706//Ubiquitin mediated proteolysis;Jak-STAT signaling pathway;Hepatitis C
NM_001300970,0,0,0,3,10,0,0,0,29,0,0,0,-,-,-,-,-
NM_001300979,0,0,0,1,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001300981,0,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
NM_001301025,43,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,K05701//Gap junction;Tight junction;Salmonella infection;Adherens junction;Epithelial cell signaling in Helicobacter pylori infection;Vibrio cholerae infection
NM_001301027,0,0,0,0,0,0,25,0,0,0,0,0,-,-,-,-,K07520//Axon guidance
NM_001301030,0,0,0,0,0,0,13,0,0,112,9,0,-,-,-,-,K05205//Glutamatergic synapse;Neuroactive ligand-receptor interaction
NM_001301033,0,0,0,7,17,0,0,0,0,0,0,0,-,-,-,-,K13749//Phototransduction
NM_001301035,0,0,0,0,0,15,0,0,0,0,0,0,-,-,-,-,-
NM_001301046,0,0,0,0,0,0,29,0,0,0,0,0,-,-,-,-,-
NM_001301060,0,0,0,0,0,0,0,0,7,0,5,0,-,-,-,-,K04575//Amyotrophic lateral sclerosis (ALS)
NM_001301061,0,0,0,0,9,0,0,0,0,0,0,0,-,-,-,-,K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis;K00719//Glycosphingolipid biosynthesis - globo series;Metabolic pathways;K01875//Biotin metabolism;Arginine and proline metabolism;Aminoacyl-tRNA biosynthesis;Metabolic pathways
NM_001301062,0,0,0,0,0,0,21,0,0,0,0,0,-,-,-,-,-
NM_001301063,0,0,0,0,0,0,0,4,3,0,0,0,-,-,-,-,K02576//Glycosaminoglycan biosynthesis - heparan sulfate;Metabolic pathways
NM_001301071,0,0,0,0,0,0,43,0,12,0,8,0,-,-,-,-,-
NM_001301076,0,0,0,0,1,0,0,0,0,0,0,0,-,-,-,-,K11827//Endocytosis;Huntington's disease;Endocrine and other factor-regulated calcium reabsorption;Synaptic vesicle cycle
NM_001301083,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,K12581//RNA degradation
NM_001301098,0,0,0,1,2,0,0,0,0,0,0,0,-,-,-,-,-
NM_001301110,0,0,0,0,0,0,0,0,28,0,0,0,-,-,-,-,-
NM_001301135,0,0,0,0,0,0,0,0,0,0,0,99,-,-,-,-,-
NM_001301138,0,0,0,0,6,0,0,0,0,0,0,0,-,-,-,-,-
NM_001301167,0,0,0,0,0,4,0,0,0,0,0,0,-,-,-,-,-
NM_001301195,0,0,0,0,0,0,0,0,0,0,3,0,-,-,-,-,K07523//Axon guidance
NM_001301197,0,0,0,0,0,0,5,0,0,0,0,0,-,-,-,-,K07523//Axon guidance
NM_001301199,0,0,0,0,0,0,0,0,6,0,0,0,-,-,-,-,K07523//Axon guidance
NM_001301200,0,0,0,0,0,0,0,66,0,0,0,0,-,-,-,-,K07523//Axon guidance
NM_001301203,0,0,0,0,0,0,48,0,9,0,0,0,-,-,-,-,-
NM_001301224,0,0,0,0,0,0,0,0,0,0,10,0,-,-,-,-,K06268//Oocyte meiosis;Amyotrophic lateral sclerosis (ALS);Wnt signaling pathway;MAPK signaling pathway;Natural killer cell mediated cytotoxicity;Glutamatergic synapse;T cell receptor signaling pathway;Apoptosis;Amphetamine addiction;Long-term potentiation;Tuberculosis;Axon guidance;VEGF signaling pathway;Alzheimer's disease;Osteoclast differentiation;B cell receptor signaling pathway;Calcium signaling pathway;HTLV-I infection
NM_001301268,0,0,0,3,0,0,1,0,0,0,0,0,-,-,-,-,-
NM_001301275,0,0,0,0,0,0,0,0,20,0,0,0,-,-,-,-,-
NM_001301317,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,K11447//Transcriptional misregulation in cancer;K06674//Cell cycle - yeast
NM_001301324,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,K00846//Fructose and mannose metabolism;Metabolic pathways
NM_001301371,0,0,1,14,7,0,0,0,0,0,0,0,-,-,-,-,-
NM_001301409,0,18,0,7,0,0,22,0,8,0,0,0,-,-,-,-,K12317//Starch and sucrose metabolism;Metabolic pathways;Galactose metabolism
NM_001301410,0,0,0,0,16,48,0,0,0,0,0,0,-,-,-,-,K12317//Starch and sucrose metabolism;Metabolic pathways;Galactose metabolism
NM_001301645,0,0,0,0,0,0,0,0,18,0,0,0,-,-,-,-,K00678//Retinol metabolism;Vitamin digestion and absorption
NM_001301648,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
NM_001301685,0,0,0,0,0,26,0,0,0,0,0,0,-,-,-,-,-
NM_001301716,0,0,0,0,0,0,0,0,0,0,2,0,-,-,-,-,K04182//Transcriptional misregulation in cancer;Cytokine-cytokine receptor interaction;Chemokine signaling pathway
NM_001301726,0,0,0,0,0,13,0,0,0,0,0,0,-,-,-,-,-
NM_001301746,0,0,0,0,0,0,0,0,6,0,0,0,-,-,-,-,-
NM_001301782,0,0,0,1,6,0,0,0,0,0,3,0,-,-,-,-,K06237//ECM-receptor interaction;Pathways in cancer;Focal adhesion;Protein digestion and absorption;Small cell lung cancer;Amoebiasis
NM_001301820,0,16,0,3,55,0,0,178,63,0,126,0,-,-,-,-,-
NM_001301851,51,0,0,0,0,40,0,0,17,0,0,0,-,-,-,-,K00797//Cysteine and methionine metabolism;Ribosome;Arginine and proline metabolism;Glutathione metabolism;beta-Alanine metabolism;Metabolic pathways
NM_001301856,0,79,4,24,0,7,0,192,20,0,104,0,-,-,-,-,K10244//Fatty acid elongation;Biosynthesis of unsaturated fatty acids
NM_001301861,0,0,0,13,0,0,0,0,0,0,0,0,-,-,-,-,K06765//Colorectal cancer;Axon guidance;Pathways in cancer;K06766//Cell adhesion molecules (CAMs)
NM_001301867,0,0,0,0,0,0,0,54,0,0,0,0,-,-,-,-,-
NM_001302082,0,0,0,0,0,36,0,0,0,0,0,0,-,-,-,-,-
NM_001302109,0,0,1,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NM_001302350,0,0,0,0,16,0,0,0,0,0,0,0,-,-,-,-,-
NM_001302453,76,26,130,39,133,0,0,0,51,0,177,0,-,-,-,-,-
NM_001302464,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,K00681//Glutathione metabolism;Taurine and hypotaurine metabolism;Cyanoamino acid metabolism;Arachidonic acid metabolism;Metabolic pathways
NOP14-AS1,0,128,202,191,549,0,52,785,223,0,580,13,-,-,-,-,-
NOVA1-AS1,0,0,0,0,0,0,0,0,75,0,0,183,-,-,-,-,-
NPHP3-AS1,0,0,0,0,0,0,0,0,31,0,0,0,-,-,-,-,-
NPSR1-AS1,0,0,0,0,0,0,25,0,8,72,1,167,-,-,-,-,-
NR2F1-AS1,0,0,0,0,0,0,29,57,33,0,14,0,-,-,-,-,-
NR2F2-AS1,0,0,0,0,0,5,0,0,100,0,11,0,-,-,-,-,-
NRAV,0,26,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
NRG1-IT1,0,0,0,0,0,0,0,0,11,127,0,0,-,-,-,-,-
NRG3-AS1,59,0,0,0,0,0,2,0,0,0,0,0,-,-,-,-,-
NRIR,59,0,0,0,0,15,39,0,0,67,11,0,-,-,-,-,-
NRSN2-AS1,0,21,0,0,0,0,0,0,26,0,0,0,-,-,-,-,-
NR_123723,0,0,0,0,0,0,0,73,0,0,0,0,-,-,-,-,-
NR_123737,0,0,0,0,0,0,0,0,0,0,1,0,-,-,-,-,-
NR_125331,0,25,1,0,5,0,0,0,82,0,6,0,-,-,-,-,-
NR_125341,0,0,0,4,0,0,0,0,0,0,0,0,-,-,-,-,K12811//Spliceosome
NR_125346,114,0,0,11,7,0,0,0,0,0,6,0,-,-,-,-,-
NR_125348,0,0,0,0,14,0,0,0,0,0,0,0,-,-,-,-,-
NR_125349,0,0,0,0,0,0,48,0,0,0,0,0,-,-,-,-,K04006//Hematopoietic cell lineage;Viral myocarditis;Complement and coagulation cascades
NR_125352,0,0,0,0,0,0,0,0,0,0,11,0,-,-,-,-,-
NR_125361,0,0,0,0,0,0,27,0,0,0,0,0,-,-,-,-,K04575//Amyotrophic lateral sclerosis (ALS)
NR_125370,0,0,0,0,0,0,18,0,0,0,0,0,-,-,-,-,K11247//Endocytosis
NR_125373,0,0,0,0,0,16,0,0,28,77,0,0,-,-,-,-,K12315//Vascular smooth muscle contraction;K05692//Viral myocarditis;Adherens junction;Phototransduction - fly;Phagosome;Salmonella infection;Arrhythmogenic right ventricular cardiomyopathy (ARVC);Influenza A;Regulation of actin cytoskeleton;Hypertrophic cardiomyopathy (HCM);Vibrio cholerae infection;Focal adhesion;Pathogenic Escherichia coli infection;Gastric acid secretion;Bacterial invasion of epithelial cells;Tight junction;Shigellosis;Leukocyte transendothelial migration;Dilated cardiomyopathy
NR_125376,0,0,0,0,0,0,0,72,9,0,0,0,-,-,-,-,-
NR_125390,0,0,0,0,0,8,17,0,13,0,0,0,-,-,-,-,-
NR_125394,0,0,0,0,0,2,0,0,0,0,0,0,-,-,-,-,-
NR_125401,0,0,0,0,0,0,0,0,8,1,0,0,-,-,-,-,-
NR_125402,62,0,0,0,0,0,0,57,0,0,0,0,-,-,-,-,K00797//beta-Alanine metabolism;Metabolic pathways;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism;K11447//Transcriptional misregulation in cancer;K00939//Metabolic pathways;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism
NR_125408,0,0,0,0,0,0,20,0,0,0,0,0,-,-,-,-,K12887//Spliceosome
NR_125409,0,1,0,0,0,0,0,57,16,0,1,1,-,-,-,-,-
NR_125422,0,0,0,0,0,0,0,0,20,0,0,0,-,-,-,-,K00939//Metabolic pathways;Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites
NR_125717,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,K13525//Protein processing in endoplasmic reticulum;Legionellosis;K14575//Ribosome biogenesis in eukaryotes
NR_125724,0,0,0,0,0,0,0,0,0,0,12,0,-,-,-,-,K04257//Olfactory transduction;K11251//Systemic lupus erythematosus;Alcoholism
NR_125730,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
NR_125739,0,165,192,83,91,0,0,1360,223,0,305,0,-,-,-,-,K10048//Tuberculosis;Transcriptional misregulation in cancer
NR_125802,0,0,0,0,0,18,0,66,0,0,1,0,-,-,-,-,-
NR_125804,0,0,0,0,0,0,0,0,11,0,16,0,-,-,-,-,-
NR_125813,0,0,0,12,1,0,8,0,43,93,12,0,-,-,-,-,-
NR_125821,0,0,0,11,10,0,0,0,12,0,28,0,-,-,-,-,K11447//Transcriptional misregulation in cancer;K06264//ECM-receptor interaction
NR_125849,0,0,0,49,52,0,0,0,50,137,56,0,-,-,-,-,-
NR_125920,0,0,0,0,0,0,0,0,47,0,0,0,-,-,-,-,-
NR_125932,0,43,139,324,510,0,33,0,3,0,76,0,-,-,-,-,K06689//Shigellosis;Ubiquitin mediated proteolysis;Protein processing in endoplasmic reticulum
NR_125960,0,0,0,0,0,0,0,0,13,0,11,0,-,-,-,-,-
NR_125979,0,361,372,346,553,0,0,103,42,0,538,0,-,-,-,-,K13126//RNA degradation;RNA transport;mRNA surveillance pathway
NR_125980,0,0,0,0,0,0,0,0,0,0,13,0,-,-,-,-,K15623//Transcriptional misregulation in cancer
NR_126005,0,0,0,0,0,7,0,0,0,0,11,0,-,-,-,-,-
NR_126022,0,0,0,0,0,0,0,0,0,0,1,0,-,-,-,-,K04257//Olfactory transduction
NR_126023,0,0,0,0,0,0,0,2,0,0,0,0,-,-,-,-,-
NR_126038,0,0,0,0,0,1,0,0,6,0,0,0,-,-,-,-,K11447//Transcriptional misregulation in cancer;K00591//Metabolic pathways;Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites;K00939//Metabolic pathways;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Purine metabolism
NR_126047,78,35,0,56,16,15,0,0,8,0,92,0,-,-,-,-,-
NR_126054,0,0,0,0,0,0,0,0,0,0,13,0,-,-,-,-,-
NR_126055,0,0,0,0,0,24,0,0,36,0,0,0,-,-,-,-,-
NR_126061,0,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
NR_126062,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
NR_126161,0,0,0,0,0,0,57,0,7,0,0,0,-,-,-,-,K00797//Metabolic pathways;beta-Alanine metabolism;Glutathione metabolism;Arginine and proline metabolism;Ribosome;Cysteine and methionine metabolism
NR_126169,0,0,0,0,0,24,25,155,0,0,0,0,-,-,-,-,K01539//Oxidative phosphorylation;Bile secretion;Proximal tubule bicarbonate reclamation;Gastric acid secretion;Carbohydrate digestion and absorption;Protein digestion and absorption;Cardiac muscle contraction;Salivary secretion;Mineral absorption;Endocrine and other factor-regulated calcium reabsorption;Pancreatic secretion;Aldosterone-regulated sodium reabsorption;K11447//Transcriptional misregulation in cancer;K00939//Purine metabolism;Pyrimidine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;K00591//Metabolic pathways;Biosynthesis of secondary metabolites;Ubiquinone and other terpenoid-quinone biosynthesis
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lnc-ATP11B-4,0,0,0,0,0,0,0,0,0,0,0,79,-,-,-,-,-
lnc-ATP11B-6,0,27,1,58,71,0,0,0,0,0,10,0,-,-,-,-,-
lnc-ATP11B-7,0,19,0,0,20,0,38,0,0,0,0,0,-,-,-,-,-
lnc-ATP11B-8,0,0,0,0,0,3,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP11B-9,0,0,0,0,0,4,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP12A-1,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
lnc-ATP12A-2,0,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
lnc-ATP13A3-1,0,0,0,0,29,0,0,0,26,0,13,0,-,-,-,-,-
lnc-ATP13A4-2,0,0,0,0,0,26,0,0,9,0,0,0,-,-,-,-,-
lnc-ATP13A4-3,0,0,0,0,0,0,0,0,0,0,8,0,-,-,-,-,-
lnc-ATP13A4-4,0,0,0,0,0,15,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP13A4-5,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,-
lnc-ATP13A5-1,0,0,0,0,0,7,0,0,21,0,10,0,-,-,-,-,-
lnc-ATP1A1-2,63,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
lnc-ATP1A1-3,0,0,0,0,0,0,0,0,21,0,0,0,-,-,-,-,-
lnc-ATP1A1OS-2,0,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
lnc-ATP1A1OS-3,0,0,0,0,0,3,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP1A1OS-6,144,0,0,0,0,0,0,0,32,0,15,0,-,-,-,-,-
lnc-ATP1A1OS-7,0,0,0,0,0,0,0,0,21,0,0,0,-,-,-,-,-
lnc-ATP1A1OS-8,0,0,0,0,0,0,0,0,5,0,0,0,-,-,-,-,-
lnc-ATP1A2-1,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
lnc-ATP1A3-1,0,0,0,0,0,0,11,58,25,4,14,0,-,-,-,-,-
lnc-ATP1B1-3,91,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP1B1-4,44,0,0,0,0,0,19,4,0,0,0,0,-,-,-,-,-
lnc-ATP1B3-1,0,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
lnc-ATP1B3-2,0,595,399,1185,1810,0,81,200,180,447,1530,1,-,-,-,-,-
lnc-ATP2A1-1,0,35,38,30,34,0,23,523,39,87,203,0,-,-,-,-,-
lnc-ATP2A2-1,0,0,0,0,0,0,0,0,0,0,3,0,-,-,-,-,-
lnc-ATP2A2-2,0,0,0,0,0,0,0,0,0,65,0,0,-,-,-,-,-
lnc-ATP2A2-3,0,0,0,0,0,0,41,0,0,0,4,0,-,-,-,-,-
lnc-ATP2A2-4,40,0,0,0,0,38,0,0,0,0,11,0,-,-,-,-,-
lnc-ATP2A2-5,0,0,0,0,0,0,29,0,1,0,0,0,-,-,-,-,-
lnc-ATP2A2-6,0,0,0,0,0,0,19,0,0,0,0,0,-,-,-,-,-
lnc-ATP2A2-7,0,0,0,0,0,0,0,21,0,0,0,0,-,-,-,-,-
lnc-ATP2A2-9,0,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
lnc-ATP2B2-1,0,0,0,0,0,0,0,0,66,0,23,0,-,-,-,-,-
lnc-ATP2B3-1,0,0,0,4,0,11,0,66,17,0,0,0,-,-,-,-,-
lnc-ATP2C1-1,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
lnc-ATP2C1-3,0,0,0,0,0,0,0,0,12,0,0,0,-,-,-,-,-
lnc-ATP2C2-1,0,68,26,36,18,0,0,100,41,0,128,0,-,-,-,-,-
lnc-ATP2C2-2,0,0,0,0,0,0,2,0,0,0,6,0,-,-,-,-,-
lnc-ATP4B-1,0,0,0,0,0,0,0,46,29,91,0,0,-,-,-,-,-
lnc-ATP5D-2,0,0,0,0,0,37,0,51,0,0,0,587,-,-,-,-,-
lnc-ATP5D-4,56,0,0,0,0,0,0,0,23,0,0,0,-,-,-,-,-
lnc-ATP5E-1,0,0,0,0,5,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP5EP2-3,0,0,0,0,0,0,0,0,16,0,0,0,-,-,-,-,-
lnc-ATP5F1-2,0,0,0,28,25,0,0,0,0,0,23,0,-,-,-,-,-
lnc-ATP5G1-1,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
lnc-ATP5G1-2,0,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
lnc-ATP5I-1,0,0,0,0,0,0,0,29,26,0,0,0,-,-,-,-,-
lnc-ATP5I-4,0,0,0,0,0,0,0,71,0,0,16,0,-,-,-,-,-
lnc-ATP5L-1,0,0,0,0,0,0,1,0,28,0,19,0,-,-,-,-,-
lnc-ATP5O-1,0,0,0,0,0,7,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP5SL-2,60,0,0,0,0,0,0,0,28,0,0,0,-,-,-,-,-
lnc-ATP6AP1L-2,0,0,0,0,0,0,17,0,0,0,0,0,-,-,-,-,-
lnc-ATP6AP1L-3,0,0,0,0,22,0,9,0,0,0,0,0,-,-,-,-,-
lnc-ATP6AP1L-5,0,0,0,0,0,0,0,0,1,0,0,134,-,-,-,-,-
lnc-ATP6AP1L-7,96,0,0,0,0,0,0,0,0,0,1,0,-,-,-,-,-
lnc-ATP6AP2-11,0,0,0,0,0,0,31,0,11,0,4,0,-,-,-,-,-
lnc-ATP6AP2-13,0,0,2,0,7,0,0,0,0,0,1,0,-,-,-,-,-
lnc-ATP6AP2-2,0,0,0,0,0,0,0,0,4,0,0,0,-,-,-,-,-
lnc-ATP6AP2-4,50,0,0,0,0,0,21,0,20,0,0,0,-,-,-,-,-
lnc-ATP6AP2-7,0,0,0,0,0,4,0,0,10,0,0,0,-,-,-,-,-
lnc-ATP6AP2-9,0,39,0,6,47,14,0,128,28,0,11,0,-,-,-,-,-
lnc-ATP6V0A1-1,0,0,0,0,0,0,0,0,0,38,0,0,-,-,-,-,-
lnc-ATP6V0A1-2,0,0,0,0,0,0,6,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V0A1-3,0,0,29,0,0,0,0,0,16,0,0,0,-,-,-,-,-
lnc-ATP6V0A4-1,0,0,0,0,0,6,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V0D2-2,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
lnc-ATP6V0E1-2,0,0,0,0,0,0,31,52,0,0,0,0,-,-,-,-,-
lnc-ATP6V0E2-1,0,0,0,0,2,26,0,0,31,0,0,0,-,-,-,-,-
lnc-ATP6V0E2-2,0,0,0,2,0,10,27,0,5,0,11,0,-,-,-,-,-
lnc-ATP6V0E2-3,171,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,-
lnc-ATP6V0E2-4,0,0,0,0,1,0,39,0,2,0,3,0,-,-,-,-,-
lnc-ATP6V0E2-5,0,0,0,0,0,1,0,27,0,0,0,0,-,-,-,-,-
lnc-ATP6V0E2-6,0,0,0,0,0,0,32,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V0E2-7,0,0,0,0,0,0,0,28,23,0,0,0,-,-,-,-,-
lnc-ATP6V1A-1,0,0,0,0,0,0,0,0,18,0,0,0,-,-,-,-,-
lnc-ATP6V1B2-10,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
lnc-ATP6V1B2-3,0,0,0,0,0,7,0,0,0,36,0,0,-,-,-,-,-
lnc-ATP6V1B2-4,0,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
lnc-ATP6V1B2-5,0,0,0,0,5,0,73,0,24,161,12,0,-,-,-,-,-
lnc-ATP6V1B2-6,0,0,0,0,0,7,16,0,11,0,0,0,-,-,-,-,-
lnc-ATP6V1B2-8,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
lnc-ATP6V1B2-9,109,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
lnc-ATP6V1C1-1,37,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1C1-2,0,0,0,0,0,0,0,0,22,0,13,0,-,-,-,-,-
lnc-ATP6V1C1-8,0,0,0,0,0,0,39,0,54,10,0,0,-,-,-,-,-
lnc-ATP6V1C1-9,0,0,0,0,0,37,13,0,45,0,0,0,-,-,-,-,-
lnc-ATP6V1C2-1,82,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
lnc-ATP6V1C2-2,151,76,122,245,324,0,0,1,28,0,169,0,-,-,-,-,-
lnc-ATP6V1C2-3,0,0,0,5,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1C2-4,0,65,0,79,110,0,0,0,0,0,67,0,-,-,-,-,-
lnc-ATP6V1C2-5,0,0,0,0,0,0,0,0,13,0,0,0,-,-,-,-,-
lnc-ATP6V1D-4,0,0,0,0,0,6,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1D-5,0,0,0,0,0,8,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1E1-3,0,0,0,0,0,0,33,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1E2-1,0,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
lnc-ATP6V1E2-10,0,0,0,0,0,12,0,0,12,0,0,0,-,-,-,-,-
lnc-ATP6V1E2-5,0,0,0,17,16,13,0,0,0,0,30,1,-,-,-,-,-
lnc-ATP6V1E2-6,0,0,0,0,0,0,0,0,20,0,0,0,-,-,-,-,-
lnc-ATP6V1E2-7,0,0,0,0,0,0,0,0,10,0,0,0,-,-,-,-,-
lnc-ATP6V1E2-8,0,0,0,0,0,0,0,0,0,0,10,0,-,-,-,-,-
lnc-ATP6V1E2-9,0,0,0,0,0,0,0,0,39,0,0,0,-,-,-,-,-
lnc-ATP6V1G2-DDX39B-3,0,2,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1G3-2,27,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
lnc-ATP6V1G3-4,0,0,0,0,0,8,61,20,62,108,2,0,-,-,-,-,-
lnc-ATP6V1G3-7,0,0,0,0,0,0,0,0,0,2,0,0,-,-,-,-,-
lnc-ATP6V1H-1,0,52,1,6,120,30,0,0,33,0,0,0,-,-,-,-,-
lnc-ATP6V1H-2,0,0,0,0,0,0,0,0,5,0,0,0,-,-,-,-,-
lnc-ATP6V1H-4,0,0,0,0,0,0,46,0,0,0,0,0,-,-,-,-,-
lnc-ATP6V1H-5,0,0,0,0,0,0,0,26,0,0,0,0,-,-,-,-,-
lnc-ATP6V1H-6,0,0,0,0,0,12,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP7B-2,0,0,0,0,0,0,0,0,24,0,0,0,-,-,-,-,-
lnc-ATP8A1-1,0,0,0,0,0,6,0,0,39,0,0,0,-,-,-,-,-
lnc-ATP8A1-2,0,0,0,0,0,15,0,0,14,0,0,0,-,-,-,-,-
lnc-ATP8A2-4,0,0,0,0,0,0,1,0,0,0,0,0,-,-,-,-,-
lnc-ATP8B3-4,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
lnc-ATP8B4-1,1,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATP9B-1,0,0,0,0,0,0,0,0,28,0,0,0,-,-,-,-,-
lnc-ATPAF1-1,0,0,0,0,0,9,0,0,0,0,0,0,-,-,-,-,-
lnc-ATPAF1-AS1-3,0,0,0,0,0,7,0,0,28,0,0,0,-,-,-,-,-
lnc-ATPAF2-2,19,731,305,642,712,32,18,718,122,1,1646,0,-,-,-,-,-
lnc-ATPBD4-1,101,0,0,0,0,0,0,0,37,0,0,0,-,-,-,-,-
lnc-ATPBD4-2,0,0,0,0,0,15,0,0,19,0,0,0,-,-,-,-,-
lnc-ATPBD4-3,0,0,0,0,0,0,32,0,6,0,0,0,-,-,-,-,-
lnc-ATPBD4-4,0,0,0,0,0,14,0,0,0,0,0,0,-,-,-,-,-
lnc-ATPBD4-5,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
lnc-ATPBD4-6,0,0,0,6,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATPBD4-7,0,0,0,0,0,1,0,0,7,0,5,0,-,-,-,-,-
lnc-ATPIF1-1,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
lnc-ATPIF1-2,165,430,479,595,1232,29,0,589,112,0,1413,58,-,-,-,-,-
lnc-ATRN-2,0,0,0,0,0,17,0,0,17,0,1,0,-,-,-,-,-
lnc-ATRN-3,0,0,0,0,0,0,0,0,22,0,0,0,-,-,-,-,-
lnc-ATRX-2,0,0,0,0,0,0,0,43,0,0,10,0,-,-,-,-,-
lnc-ATXN1-3,0,0,0,0,0,0,0,0,11,0,7,0,-,-,-,-,-
lnc-ATXN1-7,0,0,0,0,0,8,0,0,48,0,0,0,-,-,-,-,-
lnc-ATXN10-1,16,0,0,0,0,0,0,0,9,37,0,0,-,-,-,-,-
lnc-ATXN10-2,0,0,0,0,0,14,0,0,0,0,0,0,-,-,-,-,-
lnc-ATXN1L-2,0,0,0,0,0,18,0,0,12,0,0,0,-,-,-,-,-
lnc-ATXN2L-1,0,0,0,7,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATXN3-3,0,0,0,0,0,0,0,38,7,0,0,0,-,-,-,-,-
lnc-ATXN3-5,0,0,0,0,0,0,0,0,0,0,2,0,-,-,-,-,-
lnc-ATXN3L-1,0,0,0,0,0,0,21,0,31,0,0,0,-,-,-,-,-
lnc-ATXN3L-2,0,0,0,0,0,0,0,0,25,0,0,0,-,-,-,-,-
lnc-ATXN3L-3,76,0,0,0,0,0,0,0,3,0,0,0,-,-,-,-,-
lnc-ATXN3L-4,0,0,0,0,0,0,0,0,39,0,0,0,-,-,-,-,-
lnc-ATXN7-11,41,0,0,0,0,0,0,1,20,0,0,0,-,-,-,-,-
lnc-ATXN7-14,0,0,0,0,0,0,0,0,16,0,3,0,-,-,-,-,-
lnc-ATXN7-15,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
lnc-ATXN7-6,167,0,0,0,0,0,17,0,60,29,5,0,-,-,-,-,-
lnc-ATXN7L1-1,0,0,0,0,0,18,0,0,16,0,0,0,-,-,-,-,-
lnc-ATXN7L2-1,1,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-ATXN7L3B-3,0,0,0,0,0,11,0,0,29,0,0,0,-,-,-,-,-
lnc-ATXN7L3B-6,0,0,0,0,0,2,0,0,0,0,0,0,-,-,-,-,-
lnc-AUH-1,0,0,0,0,0,0,21,0,6,0,0,0,-,-,-,-,-
lnc-AUH-4,0,0,0,0,0,0,0,0,6,7,12,0,-,-,-,-,-
lnc-AUH-5,0,0,0,0,0,0,1,0,0,0,0,0,-,-,-,-,-
lnc-AUH-6,0,0,0,0,0,0,0,0,49,0,4,0,-,-,-,-,-
lnc-AURKB-3,0,0,0,0,0,0,51,0,0,0,0,0,-,-,-,-,-
lnc-AURKB-4,0,0,0,0,0,0,0,0,10,0,0,0,-,-,-,-,-
lnc-AUTS2-3,0,0,0,0,0,0,0,0,9,0,0,0,-,-,-,-,-
lnc-AUTS2-4,92,0,0,0,0,0,0,0,0,0,0,0,-,-,-,-,-
lnc-AUTS2-5,0,0,0,0,0,0,0,0,12,0,0,0,-,-,-,-,-
lnc-AVEN-1,0,0,0,0,0,0,0,0,11,0,0,0,-,-,-,-,-
lnc-AVEN-2,0,0,0,0,0,0,1,0,15,40,0,0,-,-,-,-,-
lnc-AVEN-4,0,0,0,0,0,0,0,0,13,0,13,0,-,-,-,-,-
lnc-AVIL-2,0,0,0,0,0,1,0,0,10,0,0,0,-,-,-,-,-
lnc-AVPI1-1,0,0,0,1,1,0,0,0,10,0,6,0,-,-,-,-,-
lnc-AVPR1A-1,0,0,0,0,0,0,0,0,22,0,0,0,-,-,-,-,-
lnc-AVPR1A-2,0,0,0,0,0,0,0,0,12,0,6,0,-,-,-,-,-
lnc-AVPR1A-3,0,0,0,0,0,0,0,0,14,0,0,0,-,-,-,-,-
lnc-AVPR1B-1,0,0,0,0,14,0,1,0,11,0,7,0,-,-,-,-,-
lnc-AVPR1B-2,0,0,0,0,0,0,0,0,7,0,0,0,-,-,-,-,-
lnc-AWAT2-3,0,0,0,0,0,0,0,0,17,0,0,0,-,-,-,-,-
lnc-AXIN2-2,0,0,0,0,0,23,0,0,15,10,0,0,-,-,-,-,-
lnc-AZI2-3,0,0,0,0,0,17,0,0,17,0,0,0,-,-,-,-,-
lnc-AZI2-5,0,0,0,0,0,0,0,0,0,54,0,0,-,-,-,-,-
lnc-AZI2-7,0,0,0,0,0,0,0,51,11,0,0,0,-,-,-,-,-
lnc-AZIN1-1,0,57,0,64,0,1,13,99,48,0,51,0,-,-,-,-,-
lnc-AZIN1-2,0,0,0,55,56,18,55,0,57,0,0,0,-,-,-,-,-
lnc-AZIN1-3,0,0,0,0,0,25,0,0,0,0,0,0,-,-,-,-,-
lnc-B2M-1,0,0,0,0,4,0,0,0,0,0,0,0,-,-,-,-,-
lnc-B3GALNT1-2,0,0,0,0,0,0,0,0,5,0,0,0,-,-,-,-,-
lnc-B3GALNT2-1,0,0,0,60,85,0,0,3,61,0,12,0,-,-,-,-,-
lnc-B3GALT1-1,0,0,0,0,0,0,0,0,15,0,0,0,-,-,-,-,-
lnc-B3GALT2-2,0,49,0,0,0,0,42,0,8,0,0,0,-,-,-,-,-
lnc-B3GALT2-5,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
lnc-B3GALTL-2,0,0,0,0,0,0,0,0,0,0,6,0,-,-,-,-,-
lnc-B3GALTL-4,0,0,0,0,0,0,14,0,14,0,6,0,-,-,-,-,-
lnc-B3GAT1-2,0,0,0,0,0,10,0,0,27,147,0,0,-,-,-,-,-
lnc-B3GAT1-3,0,0,0,0,0,0,0,0,12,0,7,0,-,-,-,-,-
lnc-B3GAT2-6,154,0,0,0,0,0,0,0,39,27,0,0,-,-,-,-,-
lnc-B3GAT2-7,24,0,0,0,0,23,0,0,0,0,5,0,-,-,-,-,-
lnc-B3GNT2-1,0,0,0,0,0,18,0,0,36,0,3,0,-,-,-,-,-
lnc-B3GNT3-2,0,0,0,0,0,0,5,0,1,0,0,0,-,-,-,-,-
lnc-B3GNT4-2,0,0,0,0,0,0,0,0,16,0,0,0,-,-,-,-,-
lnc-B3GNT5-10,0,0,0,0,0,0,0,0,1,0,0,0,-,-,-,-,-
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lnc-SERPINA3-4,273,0,0,0,0,10,0,0,16,1,0,1,-,-,-,-,-
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